WorldWideScience

Sample records for compulsory deep mixing

  1. Age-dependent mixing of deep-sea sediments

    International Nuclear Information System (INIS)

    Smith, C.R.; Maggaard, L.; Pope, R.H.; DeMaster, D.J.

    1993-01-01

    Rates of bioturbation measured in deep-sea sediments commonly are tracer dependent; in particular, shorter lived radiotracers (such as 234 Th) often yield markedly higher diffusive mixing coefficients than their longer-lived counterparts (e.g., 210 Pb). At a single station in the 1,240-m deep Santa Catalina Basin, the authors document a strong negative correlation between bioturbation rate and tracer half-life. Sediment profiles of 234 Th (half-life = 24 days) yield an average mixing coefficient (60 cm 2 y -1 ) two orders of magnitude greater than that for 210 Pb (half-life = 22 y, mean mixing coefficient = 0.4 cm 2 y -1 ). A similar negative relationship between mixing rate and tracer time scale is observed at thirteen other deep-sea sites in which multiple radiotracers have been used to assess diffusive mixing rates. This relationship holds across a variety of radiotracer types and time scales. The authors hypothesize that this negative relationship results from age-dependent mixing, a process in which recently sedimented, food-rich particles are ingested and mixed at higher rates by deposit feeders than are older, food-poor particles. Results from an age-dependent mixing model demonstrate that this process indeed can yield the bioturbation-rate vs. tracer-time-scale correlations observed in deep-sea sediments. Field data on mixing rates of recently sedimented particles, as well as the radiotracer activity of deep-sea deposit feeders, provide strong support for the age-dependent mixing model. The presence of age-dependent mixing in deep-sea sediments may have major implications for diagenetic modeling, requiring a match between the characteristic time scales of mixing tracers and modeled reactants. 102 refs., 6 figs., 5 tabs

  2. Deep Attack Weapons Mix Study (DAWMS) Case Study

    National Research Council Canada - National Science Library

    Bexfield, James

    2001-01-01

    .... This report describes the process used to conduct the Deep Attack Weapons Mix Study (DAWMS) in 1995-1997. This case study focuses on the weapons being procured by the Services and whether a joint viewpoint would result in a more effective mix...

  3. Basic Aspects of Deep Soil Mixing Technology Control

    Science.gov (United States)

    Egorova, Alexandra A.; Rybak, Jarosław; Stefaniuk, Damian; Zajączkowski, Przemysław

    2017-10-01

    Improving a soil is a process of increasing its physical/mechanical properties without changing its natural structure. Improvement of soil subbase is reached by means of the knitted materials, or other methods when strong connection between soil particles is established. The method of DSM (Deep Soil Mixing) columns has been invented in Japan in 1970s. The main reason of designing cement-soil columns is to improve properties of local soils (such as strength and stiffness) by mixing them with various cementing materials. Cement and calcium are the most commonly used binders. However new research undertaken worldwide proves that apart from these materials, also gypsum or fly ashes can also be successfully implemented. As the Deep Soil Mixing is still being under development, anticipating mechanical properties of columns in particular soils and the usage of cementing materials in formed columns is very difficult and often inappropriate to predict. That is why a research is carried out in order to find out what binders and mixing technology should be used. The paper presents several remarks on the testing procedures related to quality and capacity control of Deep Soil Mixing columns. Soil improvement methods, their advantages and limitations are briefly described. The authors analyse the suitability of selected testing methods on subsequent stages of design and execution of special foundations works. Chosen examples from engineering practice form the basis for recommendations for the control procedures. Presented case studies concerning testing the on capacity field samples and laboratory procedures on various categories of soil-cement samples were picked from R&D and consulting works offered by Wroclaw University of Science and Technology. Special emphasis is paid to climate conditions which may affect the availability of performing and controlling of DSM techniques in polar zones, with a special regard to sample curing.

  4. [Techniques for nutrition education in particular for maternal and compulsory schools (author's transl)].

    Science.gov (United States)

    Alberti, A F

    1975-01-01

    After an introduction on the various factors involved in food habits of humans, the A. is calling the attention on the importance of nutrition education, examining then some of the programs in use. Already in the maternal school the child can learn nutrition with applicative plays. It is compulsory to teach and follow also the in parents. For the compulsory school the nutrition should be taught as such or integrated in other courses as geography, history, mathematics and science. For adults the deep-seated food habits are making more difficult the educational programs. For successful results in nutrition education is essential that the programs are well planned and carried out from well trained personnel not only in nutritional sciences but also in education, cultural anthropology, psicology and sociology.

  5. Near-inertial waves and deep ocean mixing

    Science.gov (United States)

    Shrira, V. I.; Townsend, W. A.

    2013-07-01

    For the existing pattern of global oceanic circulation to exist, there should be sufficiently strong turbulent mixing in the abyssal ocean, the mechanisms of which are not well understood as yet. The review discusses a plausible mechanism of deep ocean mixing caused by near-inertial waves in the abyssal ocean. It is well known how winds in the atmosphere generate near-inertial waves in the upper ocean, which then propagate downwards losing their energy in the process; only a fraction of the energy at the surface reaches the abyssal ocean. An open question is whether and, if yes, how these weakened inertial motions could cause mixing in the deep. We review the progress in the mathematical description of a mechanism that results in an intense breaking of near-inertial waves near the bottom of the ocean and thus enhances the mixing. We give an overview of the present state of understanding of the problem covering both the published and the unpublished results; we also outline the key open questions. For typical ocean stratification, the account of the horizontal component of the Earth's rotation leads to the existence of near-bottom wide waveguides for near-inertial waves. Due to the β-effect these waveguides are narrowing in the poleward direction. Near-inertial waves propagating poleward get trapped in the waveguides; we describe how in the process these waves are focusing more and more in the vertical direction, while simultaneously their group velocity tends to zero and wave-induced vertical shear significantly increases. This causes the development of shear instability, which is interpreted as wave breaking. Remarkably, this mechanism of local intensification of turbulent mixing in the abyssal ocean can be adequately described within the framework of linear theory. The qualitative picture is similar to wind wave breaking on a beach: the abyssal ocean always acts as a surf zone for near-inertial waves.

  6. Near-inertial waves and deep ocean mixing

    International Nuclear Information System (INIS)

    Shrira, V I; Townsend, W A

    2013-01-01

    For the existing pattern of global oceanic circulation to exist, there should be sufficiently strong turbulent mixing in the abyssal ocean, the mechanisms of which are not well understood as yet. The review discusses a plausible mechanism of deep ocean mixing caused by near-inertial waves in the abyssal ocean. It is well known how winds in the atmosphere generate near-inertial waves in the upper ocean, which then propagate downwards losing their energy in the process; only a fraction of the energy at the surface reaches the abyssal ocean. An open question is whether and, if yes, how these weakened inertial motions could cause mixing in the deep. We review the progress in the mathematical description of a mechanism that results in an intense breaking of near-inertial waves near the bottom of the ocean and thus enhances the mixing. We give an overview of the present state of understanding of the problem covering both the published and the unpublished results; we also outline the key open questions. For typical ocean stratification, the account of the horizontal component of the Earth's rotation leads to the existence of near-bottom wide waveguides for near-inertial waves. Due to the β-effect these waveguides are narrowing in the poleward direction. Near-inertial waves propagating poleward get trapped in the waveguides; we describe how in the process these waves are focusing more and more in the vertical direction, while simultaneously their group velocity tends to zero and wave-induced vertical shear significantly increases. This causes the development of shear instability, which is interpreted as wave breaking. Remarkably, this mechanism of local intensification of turbulent mixing in the abyssal ocean can be adequately described within the framework of linear theory. The qualitative picture is similar to wind wave breaking on a beach: the abyssal ocean always acts as a surf zone for near-inertial waves. (paper)

  7. Field testing of stiffened deep cement mixing piles under lateral cyclic loading

    Science.gov (United States)

    Raongjant, Werasak; Jing, Meng

    2013-06-01

    Construction of seaside and underground wall bracing often uses stiffened deep cement mixed columns (SDCM). This research investigates methods used to improve the level of bearing capacity of these SDCM when subjected to cyclic lateral loading via various types of stiffer cores. Eight piles, two deep cement mixed piles and six stiffened deep cement mixing piles with three different types of cores, H shape cross section prestressed concrete, steel pipe, and H-beam steel, were embedded though soft clay into medium-hard clay on site in Thailand. Cyclic horizontal loading was gradually applied until pile failure and the hysteresis loops of lateral load vs. lateral deformation were recorded. The lateral carrying capacities of the SDCM piles with an H-beam steel core increased by 3-4 times that of the DCM piles. This field research clearly shows that using H-beam steel as a stiffer core for SDCM piles is the best method to improve its lateral carrying capacity, ductility and energy dissipation capacity.

  8. Compulsory Schooling Laws and Migration Across European Countries.

    Science.gov (United States)

    Aparicio Fenoll, Ainhoa; Kuehn, Zoë

    2017-12-01

    Educational attainment is a key factor for understanding why some individuals migrate and others do not. Compulsory schooling laws, which determine an individual's minimum level of education, can potentially affect migration. We test whether and how increasing the length of compulsory schooling influences migration of affected cohorts across European countries, a context where labor mobility is essentially free. We construct a novel database that includes information for 31 European countries on compulsory education reforms passed between 1950 and 1990. Combining this data with information on recent migration flows by cohorts, we find that an additional year of compulsory education reduces the number of individuals from affected cohorts who migrate in a given year by 9 %. Our results rely on the exogeneity of compulsory schooling laws. A variety of empirical tests indicate that European legislators did not pass compulsory education reforms as a reaction to changes in emigration rates or educational attainment.

  9. 16 CFR 1118.3 - Compulsory processes and service.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Compulsory processes and service. 1118.3... Investigations, Inspections, and Inquiries § 1118.3 Compulsory processes and service. (a) In addition to or in...) Depositions; and (4) General or special orders. (b) Service in connection with any of the compulsory processes...

  10. Compulsory Treatment in Anorexia Nervosa : A Review

    NARCIS (Netherlands)

    Elzakkers, Isis F. F. M.; Danner, Unna N.; Hoek, Hans W.; Schmidt, Ulrike; van Elburg, Annemarie A.

    2014-01-01

    ObjectiveCompulsory in-patient refeeding of patients with severe anorexia nervosa (AN) has caused considerable controversy. The effects of such treatment on longer-term outcome are not well known. The objective of this article is to review the evidence on the outcome of compulsory treatment for AN.

  11. Deep soil mixing for reagent delivery and contaminant treatment

    International Nuclear Information System (INIS)

    Korte, N.; Gardner, F.G.; Cline, S.R.; West, O.R.

    1997-01-01

    Deep soil mixing was evaluated for treating clay soils contaminated with TCE and its byproducts at the Department of Energy's Kansas City Plant. The objective of the project was to evaluate the extent of limitations posed by the stiff, silty-clay soil. Three treatment approaches were tested. The first was vapor stripping. In contrast to previous work, however, laboratory treatability studies indicated that mixing saturated, clay soil was not efficient unless powdered lime was added. Thus, powder injection of lime was attempted in conjunction with the mixing/stripping operation. In separate treatment cells, potassium permanganate solution was mixed with the soil as a means of destroying contaminants in situ. Finally, microbial treatment was studied in a third treatment zone. The clay soil caused operational problems such as breakage of the shroud seal and frequent reagent blowouts. Nevertheless, treatment efficiencies of more than 70% were achieved in the saturated zone with chemical oxidation. Although expensive ($1128/yd 3 ), there are few alternatives for soils of this type

  12. 47 CFR 80.59 - Compulsory ship inspections.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Compulsory ship inspections. 80.59 Section 80... STATIONS IN THE MARITIME SERVICES Applications and Licenses § 80.59 Compulsory ship inspections. (a) Inspection of ships subject to the Communications Act or the Safety Convention. (1) The FCC will not normally...

  13. The case against libertarian arguments for compulsory vaccination.

    Science.gov (United States)

    Bernstein, Justin

    2017-11-01

    In a recent paper in this journal, Jason Brennan correctly notes that libertarians struggle to justify a policy of compulsory vaccination. The most straightforward argument that justifies compulsory vaccination is that such a policy promotes welfare. But libertarians cannot make this argument because they claim that the state is justified only in protecting negative rights, not in promoting welfare. I consider two representative libertarian attempts to justify compulsory vaccination, and I argue that such arguments are unsuccessful. They either fail to show that the state is justified in implementing the policy or overgeneralise. I suggest that Brennan's solution is especially well motivated insofar as it addresses the shortcomings of these arguments. Brennan argues that we violate the rights of others by participating in an activity that imposes an unacceptable collective risk of harm. Going unvaccinated is an activity that imposes an unacceptable collective risk of harm, and thus amounts to a rights violation. So, the state can implement a policy of compulsory vaccination I object, however, that Brennan's delineation of acceptable and unacceptable risk implicitly rests on classical liberal rather than libertarian principles; he justifies compulsory vaccination on the grounds that it promotes welfare. I also object that Brennan's argument would entail significant departures from libertarian institutional arrangements. This leaves libertarians with a choice: they can develop new arguments to demonstrate that their position is compatible with compulsory vaccination, or they can accept that their view entails the impermissibility of compulsory vaccination, and argue that this is not an unpalatable implication of their view. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  14. Ozone mixing ratios inside tropical deep convective clouds from OMI satellite measurements

    Directory of Open Access Journals (Sweden)

    J. R. Ziemke

    2009-01-01

    Full Text Available We have developed a new technique for estimating ozone mixing ratio inside deep convective clouds. The technique uses the concept of an optical centroid cloud pressure that is indicative of the photon path inside clouds. Radiative transfer calculations based on realistic cloud vertical structure as provided by CloudSat radar data show that because deep convective clouds are optically thin near the top, photons can penetrate significantly inside the cloud. This photon penetration coupled with in-cloud scattering produces optical centroid pressures that are hundreds of hPa inside the cloud. We combine measured column ozone and the optical centroid cloud pressure derived using the effects of rotational-Raman scattering to estimate O3 mixing ratio in the upper regions of deep convective clouds. The data are obtained from the Ozone Monitoring Instrument (OMI onboard NASA's Aura satellite. Our results show that low O3 concentrations in these clouds are a common occurrence throughout much of the tropical Pacific. Ozonesonde measurements in the tropics following convective activity also show very low concentrations of O3 in the upper troposphere. These low amounts are attributed to vertical injection of ozone poor oceanic boundary layer air during convection into the upper troposphere followed by convective outflow. Over South America and Africa, O3 mixing ratios inside deep convective clouds often exceed 50 ppbv which are comparable to mean background (cloud-free amounts and are consistent with higher concentrations of injected boundary layer/lower tropospheric O3 relative to the remote Pacific. The Atlantic region in general also consists of higher amounts of O3 precursors due to both biomass burning and lightning. Assuming that O3 is well mixed (i.e., constant mixing ratio with height up to the tropopause, we can estimate the stratospheric column O3 over

  15. 16 CFR 1605.3 - Compulsory processes and the service thereof.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Compulsory processes and the service thereof... Investigations, Inspections and Inquiries § 1605.3 Compulsory processes and the service thereof. (a) In addition... inquired of. (c) The date of service of any form of compulsory process shall be the date on which the...

  16. 19 CFR 210.61 - Discovery and compulsory process.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Discovery and compulsory process. 210.61 Section 210.61 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE ADJUDICATION AND ENFORCEMENT Temporary Relief § 210.61 Discovery and compulsory...

  17. Crime, Compulsory Schooling Laws and Education

    OpenAIRE

    Brian Bell; Rui Costa; Stephen Machin

    2015-01-01

    Do compulsory schooling laws reduce crime? Previous evidence for the U.S. from the 1960s and 1970s suggests they do, primarily working through their effect on educational attainment to generate a causal impact on crime. In this paper, we consider whether more recent experience replicates this. There are two key findings. First, there is a strong and consistent negative effect on crime from stricter compulsory schooling laws. Second, there is a weaker and sometimes non-existent link between su...

  18. Compulsory acquisition of shares buyer, other shareholders, abuse of right of compulsory acquisition of shares

    Directory of Open Access Journals (Sweden)

    Arsić Zoran V.

    2015-01-01

    Full Text Available Company Act of Republic of Serbia includes mechanism for the compulsory acquisition of the shareholdings of minority shareholders. Technically this procedure is effected on the basis of the shareholders assembly resolution. Buyer is shareholder who has at least 90% of share capital and at least 90% of votes. Shares owned by entity under his dominant influence will be treated as shares of that shareholder provided that dominant influence exists at least one year. Company's own shares, and shares subject o a pledge do not represent shares of other shareholders. There are several actions which may be treated as abuse of right of compulsory acquisition of shares.

  19. Implementing Nunavut Education Act: Compulsory School Attendance Policy

    Science.gov (United States)

    Kwarteng, E. Fredua

    2006-01-01

    This paper discusses the implementation of Nunavut compulsory school attendance policy as part of the Nunavut Education Act (2002). Using a bottom-up approach to policy implementation in the literature and the author's six years teaching experience in Nunavut, the paper argues that the compulsory school attendance policy may not achieve its…

  20. Leadership: professional communities of leadership practice in post-compulsory education

    OpenAIRE

    Jameson, Jill

    2008-01-01

    Summary: This is a paper that reviews and outlines the academic basis behind leadership in the post-compulsory setting.\\ud Description: Leadership has been for some years a key area of strategic and operational importance in the UK post-compulsory sector - this publication aims to addresss some of the issues surrounding this topic. It discusses theories and definitions of leadership, leader professionalism and post-compulsory education. A collaborative model of professional leadership is reco...

  1. Family Economy and Its Implementation on Compulsory Education Program

    Directory of Open Access Journals (Sweden)

    Neni Hendaryati

    2015-12-01

    Full Text Available This research aims to determine and describe family economy and the implementation of nine-year compulsory education program at Kajenengan village, Bojong Sub District of Tegal in 2014. It was a qualitative descriptive study. The population of study was 1011 family leaders. This research used purposive sampling technique and 252 family leaders or about 25% of the population were as samples. Data were collected by observation, interview and documentation. Then, the data was analyzed by using data reduction, data display, and concluding. Findings show that the obstacles of social and economy faced by family: 47.20% of Kajenengan villagers are as farm labors, 28,57 % of  villagers get the average income per day from IDR 21,000 up to IDR 30,000,  33.73% of them have 5-6 family members in their nuclear family, and 32.80% of them who prioritize in education, especially on nine-years compulsory education program.  Then, there are only 8.73% of samples who implement the nine-year compulsory education program. Moreover, 47.62% family leaders say that most of their family members join the nine-year compulsory education and 43.65% of the family leaders say that all of their family members do not join the nine-year compulsory education at all.

  2. Comparing Youth Opinions toward Compulsory Voting across Five Countries

    Science.gov (United States)

    Pesek, Jessamay T.

    2014-01-01

    This study uses a comparative case study design to examine youth (ages 13-20) opinions toward compulsory voting across five democratic countries: Colombia, Ecuador, Mexico, Peru, and the United States. Youth responses toward compulsory voting demonstrate how youth come to learn about citizen rights and responsibilities with varied understandings…

  3. Introduction of China's Compulsory Product Certification System (Ⅰ)

    Institute of Scientific and Technical Information of China (English)

    无

    2004-01-01

    @@ Why does China establish a new Compulso-ry Product Certification System? For a long time, our compulsory product certification system has had problems such as lack of a unified management department, repeated assessments,repeated charging and no separation between certification activities and behaviors of law enforcement.The most obvious problem is that two certification management systems exist respectively for domestic products and imported products.

  4. Surface water iron supplies in the Southern Ocean sustained by deep winter mixing

    CSIR Research Space (South Africa)

    Tagliabue, A

    2014-04-01

    Full Text Available Low levels of iron limit primary productivity across much of the Southern Ocean. At the basin scale, most dissolved iron is supplied to surfacewaters from subsurface reservoirs, because land inputs are spatially limited. Deep mixing in winter...

  5. Object and subject of evasion of taxes and other compulsory payments

    Directory of Open Access Journals (Sweden)

    Koval L.

    2014-01-01

    Full Text Available The paper is devoted to such topical issue of Criminal Law as Object and Subject of Evasion of Taxes and Other Compulsory Payments. There are analyzed researched crime determination problems, which are connected with subject and object of tax and other compulsory payments evasion. In the course of the research, the author has made the conclusions that the object of the evasion of taxes and other compulsory payments group is the national economic interests. The direct object is the national economic interests in the sphere of state revenues or the national fiscal interests. While analyzing the law and regulations it is concluded that the subject of the evasion of taxes and other compulsory payments is the tax base (income, property, expenses and consumption, taxes, state and local government fees, as well as other payments determined by the State. The author has also concluded that the subject of the evasion of taxes and other compulsory payments does not include increase in the tax principal debt, fine and late charge, which are covered by the financial responsibility. The subject of the evasion of taxes and other compulsory payments may not include also income from illegal activity or proceeds resulting from criminal offences.

  6. Does mental health service integration affect compulsory admissions?

    Directory of Open Access Journals (Sweden)

    André I. Wierdsma

    2009-09-01

    Full Text Available Background: Over recent years, the number of compulsory admissions in many countries has increased, probably as a result of the shift from inpatient to outpatient mental health care. This might be mitigated by formal or collaborative relationships between services. Methods: In a retrospective record linkage study, we compared two neighboring districts, varying in level of service integration. Two periods were combined: 1991–1993 and 2001–2003. We included patients aged 18–60, who had a first emergency compulsory admission (n=830. Their psychiatric history was assessed, and service-use after admission was monitored over a 12-month follow-up. Results: Over a 10-year period, compulsory admission rates increased by 47%. Difference in relative increase between the integrated and non-integrated services was 14%. Patient characteristics showed different profiles in the two districts. Length of stay was >10 days shorter in the integrated district, where the proportion of involuntary readmissions decreased more, and where aftercare was swift and provided to about 10% more patients than in the non-integrated district. Conclusions: Services outcomes showed better results where mental healthcare was more integrated. However, limited effects were found and other factors than integration of services may be more important in preventing compulsory admissions.

  7. 47 CFR 80.307 - Compulsory use of radiotelegraph auto alarm.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Compulsory use of radiotelegraph auto alarm. 80.307 Section 80.307 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL... Safety Watches § 80.307 Compulsory use of radiotelegraph auto alarm. The radiotelegraph auto alarm...

  8. 77 FR 44179 - Mechanical and Digital Phonorecord Delivery Compulsory License

    Science.gov (United States)

    2012-07-27

    ... of account, certified by a certified public accountant, shall be filed for every compulsory license... Statements of Account, certified by a certified public accountant, shall be filed for every compulsory... it to the public for private use. The mechanical license may be used once phonorecords of a...

  9. The CPD Needs of Mentors in Post-Compulsory Initial Teacher Training in England

    Science.gov (United States)

    Ingleby, Ewan; Hunt, John

    2008-01-01

    This paper discusses the compulsory professional development (CPD) needs of mentors within post-compulsory Initial Teacher Training (ITT) provision in England. The discussion applies the ideas of Weber, Foucault, Habermas and Bourdieu in interpreting the implications for post-compulsory ITT mentor CPD training. The paper's primary and secondary…

  10. Mesopelagic Prokaryotes Alter Surface Phytoplankton Production during Simulated Deep Mixing Experiments in Eastern Mediterranean Sea Waters

    Directory of Open Access Journals (Sweden)

    Or Hazan

    2018-01-01

    Full Text Available Mesopelagic prokaryotes (archaea and bacteria, which are transported together with nutrient-rich intermediate-water to the surface layer by deep convection in the oceans (e.g., winter mixing, upwelling systems, can interact with surface microbial populations. This interaction can potentially affect production rates and biomass of surface microbial populations, and thus play an important role in the marine carbon cycle and oceanic carbon sequestration. The Eastern Mediterranean Sea (EMS is one of the most oligotrophic and warm systems in the world's oceans, with usually very shallow winter mixing (<200 m and lack of large-size spring algal blooms. In this study, we collected seawater (0–1,500 m in 9 different cruises at the open EMS during both the stratified and the mixed seasons. We show that the EMS is a highly oligotrophic regime, resulting in low autotrophic biomass and primary productivity and relatively high heterotrophic prokaryotic biomass and production. Further, we simulated deep water mixing in on-board microcosms using Levantine surface (LSW, ~0.5 m and intermediate (LIW, ~400 m waters at a 9:1 ratio, respectively and examined the responses of the microbial populations to such a scenario. We hypothesized that the LIW, being nutrient-rich (e.g., N, P and a “hot-spot” for microbial activity (due to the warm conditions that prevail in these depths, may supply the LSW with not only key-limiting nutrients but also with viable and active heterotrophic prokaryotes that can interact with the ambient surface microbial population. Indeed, we show that LIW heterotrophic prokaryotes negatively affected the surface phytoplankton populations, resulting in lower chlorophyll-a levels and primary production rates. This may be due to out-competition of phytoplankton by LIW populations for resources and/or by a phytoplankton cell lysis via viral infection. Our results suggest that phytoplankton in the EMS may not likely form blooms, even after

  11. Groundwater Mixing Process Identification in Deep Mines Based on Hydrogeochemical Property Analysis

    Directory of Open Access Journals (Sweden)

    Bo Liu

    2016-12-01

    Full Text Available Karst collapse columns, as a potential water passageway for mine water inrush, are always considered a critical problem for the development of deep mining techniques. This study aims to identify the mixing process of groundwater deriving two different limestone karst-fissure aquifer systems. Based on analysis of mining groundwater hydrogeochemical properties, hydraulic connection between the karst-fissure objective aquifer systems was revealed. In this paper, piper diagram was used to calculate the mixing ratios at different sampling points in the aquifer systems, and PHREEQC Interactive model (Version 2.5, USGS, Reston, VA, USA, 2001 was applied to modify the mixing ratios and model the water–rock interactions during the mixing processes. The analysis results show that the highest mixing ratio is 0.905 in the C12 borehole that is located nearest to the #2 karst collapse column, and the mixing ratio decreases with the increase of the distance from the #2 karst collapse column. It demonstrated that groundwater of the two aquifers mixed through the passage of #2 karst collapse column. As a result, the proposed Piper-PHREEQC based method can provide accurate identification of karst collapse columns’ water conductivity, and can be applied to practical applications.

  12. Deep geologic disposal of mixed waste in bedded salt: The Waste Isolation Pilot Plant

    International Nuclear Information System (INIS)

    Rempe, N.T.

    1993-01-01

    Mixed waste (i.e., waste that contains both chemically hazardous and radioactive components) poses a moral, political, and technical challenge to present and future generations. But an international consensus is emerging that harmful byproducts and residues can be permanently isolated from the biosphere in a safe and environmentally responsible manner by deep geologic disposal. To investigate and demonstrate such disposal for transuranic mixed waste, derived from defense-related activities, the US Department of Energy has prepared the Waste Isolation Pilot Plant (WIPP) near Carlsbad, New Mexico. This research and development facility was excavated approximately at the center of a 600 m thick sequence of salt (halite) beds, 655 m below the surface. Proof of the long-term tectonic and hydrological stability of the region is supplied by the fact that these salt beds have remained essentially undisturbed since they were deposited during the Late Permian age, approximately 225 million years ago. Plutonium-239, the main radioactive component of transuranic mixed waste, has a half-life of 24,500 years. Even ten half-lives of this isotope - amounting to about a quarter million years, the time during which its activity will decline to background level represent only 0.11 percent of the history of the repository medium. Therefore, deep geologic disposal of transuranic mixed waste in Permian bedded salt appears eminently feasible

  13. Cultivating a Troubled Consciousness: Compulsory sound-mindedness and complicity in oppression

    Directory of Open Access Journals (Sweden)

    C. Chapman

    2013-11-01

    Full Text Available Implicating oneself in oppression provokes uncertainty, shame and anxiety, and identity destabilizations. Yet anti-oppressive texts often denigrate these experiences, participating in forces I call “compulsory sound-mindedness.” Narratives of three women confronting their complicity illustrate the workings of compulsory sound-mindedness: a white Canadian recognizing the racism in her development work and both a white woman and a racialized Muslim reflecting on their complicity in ongoing Canadian colonization. The three narratives devalue affect, uncertainty, and destabilized identity. They also reveal these denigrated experiences as fundamental to personal-is-political ethical transformation. Compulsory sound-mindedness cannot consistently prevent people from journeying with pain, uncertainty, and coming undone. But when people undertake such journeys, compulsory sound-mindedness frames pain, identity destabilization, and uncertainty as regrettable and without value. I advocate that people cultivate a “troubled consciousness” by journeying with internalized accountability narratives, uncertainties, painful feelings, and destabilizations of a straightforwardly moral self.

  14. Implementation of deep soil mixing at the Kansas City Plant

    International Nuclear Information System (INIS)

    Gardner, F.G.; Korte, N.; Strong-Gunderson, J.; Siegrist, R.L.; West, O.R.; Cline, S.R.

    1998-01-01

    In July 1996, the US Department of Energy (DOE) Kansas City Plant (KCP), AlliedSignal Federal Manufacturing and Technologies, and Oak Ridge National Laboratory (ORNL), conducted field-scale tests of in situ soil mixing and treatment technologies within the Northeast Area (NEA) of the KCP at the Former Ponds site. This demonstration, testing, and evaluation effort was conducted as part of the implementation of a deep soil mixing (DSM) innovative remedial technology demonstration project designed to test DSM in the low-permeability clay soils at the KCP. The clay soils and groundwater beneath this area are contaminated by volatile organic compounds (VOCs), primarily trichloroethene (TCE) and 1,2-dichloroethene (1,2-DCE). The demonstration project was originally designed to evaluate TCE and 1,2-DCE removal efficiency using soil mixing coupled with vapor stripping. Treatability study results, however, indicated that mixed region vapor stripping (MRVS) coupled with calcium oxide (dry lime powder) injection would improve TCE and 1,2-DCE removal efficiency in saturated soils. The scope of the KCP DSM demonstration evolved to implement DSM with the following in situ treatment methodologies for contaminant source reduction in soil and groundwater: DSM/MRVS coupled with calcium oxide injection; DSM/bioaugmentation; and DSM/chemical oxidation using potassium permanganate. Laboratory treatability studies were started in 1995 following collection of undisturbed soil cores from the KCP. These studies were conducted at ORNL, and the results provided information on optimum reagent concentrations and mixing ratios for the three in situ treatment agents to be implemented in the field demonstration

  15. The compulsory psychiatric regime in Hong Kong: Constitutional and ethical perspectives.

    Science.gov (United States)

    Cheung, Daisy

    This article examines the compulsory psychiatric regime in Hong Kong. Under section 36 of the Mental Health Ordinance, which authorises long-term detention of psychiatric patients, a District Judge is required to countersign the form filled out by the registered medical practitioners in order for the detention to be valid. Case law, however, has shown that the role of the District Judge is merely administrative. This article suggests that, as it currently stands, the compulsory psychiatric regime in Hong Kong is unconstitutional because it fails the proportionality test. In light of this conclusion, the author proposes two solutions to deal with the issue, by common law or by legislative reform. The former would see an exercise of discretion by the courts read into section 36, while the latter would involve piecemeal reform of the relevant provisions to give the courts an explicit discretion to consider substantive issues when reviewing compulsory detention applications. The author argues that these solutions would introduce effective judicial supervision into the compulsory psychiatric regime and safeguard against abuse of process. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Mixed Pyolaryngocele: A Rare Case of Deep Neck Infection

    Directory of Open Access Journals (Sweden)

    Rachid Mahdoufi

    2017-07-01

    Full Text Available Introduction: Pyolaryngocele is a very rare and serious complication of laryngocele. It can present as deep neck space infection and mislead the diagnosis. Our aim is to bring this unusual entity to the attention of surgeons and describe its clinical features. Case Report: We report a case of a 45-year-old male patient with a five-week history of neck swelling, dysphonia, dyspnea and odynophagia. An urgent CT scan showed a mixed pyolaryngocele. The management consisted of a high dose antibiotic and an excision of the residual laryngocele via an external approach. Conclusion: A pyolaryngocele is an unusual complication of laryngocele, which becomes secondarily infected, causing many symptoms. Removing the laryngocele is still the best treatment option to prevent this complication and recurrence.

  17. 37 CFR 256.2 - Royalty fee for compulsory license for secondary transmission by cable systems.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Royalty fee for compulsory... ADJUSTMENT OF ROYALTY FEE FOR CABLE COMPULSORY LICENSE § 256.2 Royalty fee for compulsory license for... receipts be reduced to less than $10,400. The royalty fee payable under this paragraph shall be 0.5 of 1...

  18. Implementation of Compulsory Study 12 Year Policy to Increase Education Quality in Kudus Regency

    Directory of Open Access Journals (Sweden)

    Asih Widi Lestari

    2015-02-01

    Full Text Available Education is an important instrument in improving the human resources quality. Kudus Regency has implemented compulsory study since 2010 through Kudus Regency Regional Regulation Number 2/ 2010 about Compulsory Study 12 (Twelve Years. While, Central Government issued compulsory study 12 year policy in June 2013 through Ministry of Education and Culture Regulation Number 80/2013 about Universal Secondary Education. Obviously, this is a bold step of Kudus Regency Government in improving the education quality at Kudus Regency. The research objectives are: to know, analyze, and describe about Implementation of compulsory study 12 years policy to increase education in Kudus Regency; and to know, analyze, and describe about supporting and inhibiting factors toward implementation of compulsory study 12 years policy to increase education quality in Kudus Regency. This research resulted that the implementation compulsory study 12 years policy in Kudus Regency has been successfully, viewed from the actor that completely carry out their duties and responsibilities; the existence of funding and programs from Kudus Regency Government and Central Government is supporting the mechanism implementation in accordance with the provisions. The compulsory study 12 years policy in Kudus Regency had positive impact in improving the education quality at Kudus Regency, it is seen from the increase of Gross Enrollment Ratio (GER for secondary education from 60% in 2008 to 80,59% in 2013. The success in improving the education quality is also seen from achievement of Kudus Regency in obtained champions in various championships. The supporting factors are The content of the Kudus Regency Regional Regulation Number 2/ 2010 about Compulsory Study 12 Years and the Minister of Education and Culture Regulation Number 80/ 2013 about Universal Secondary Education which clear and easy to understand; the willingness of Kudus Society in receiving the compulsory study 12 years policy

  19. Corium quench in deep pool mixing experiments

    International Nuclear Information System (INIS)

    Spencer, B.W.; McUmber, L.; Gregorash, D.; Aeschlimann, R.; Sienicki, J.J.

    1985-01-01

    The results of two recent corium-water thermal interaction (CWTI) tests are described in which a stream of molten corium was poured into a deep pool of water in order to determine the mixing behavior, the corium-to-water heat transfer rates, and the characteristic sizes of the quenched debris. The corium composition was 60% UO 2 , 16% ZrO 2 , and 24% stainless steel by weight; its initial temperature was 3080 K, approx.160 K above the oxide phase liquidus temperature. The corium pour stream was a single-phase 2.2 cm dia liquid column which entered the water pool in film boiling at approx.4 m/s. The water subcooling was 6 and 75C in the two tests. Test results showed that with low subcooling, rapid steam generation caused the pool to boil up into a high void fraction regime. In contrast, with large subcooling no net steam generation occurred, and the pool remained relatively quiescent. Breakup of the jet appeared to occur by surface stripping. In neither test was the breakup complete during transit through the 32 cm deep water pool, and molten corium channeled to the base where it formed a melt layer. The characteristic heat transfer rates measured 3.5 MJ/s and 2.7 MJ/s during the fall stage for small and large subcooling, respectively; during the initial stage of bed quench, the surface heat fluxes measured 2.4 MW/m 2 and 3.7 MW/m 2 , respectively. A small mass of particles was formed in each test, measuring typically 0.1 to 1 mm and 1 to 5 mm dia for the large and small subcooling conditions, respectively. 9 refs., 13 figs., 1 tab

  20. On Financial Support System for Compulsory Education in China's Western Minority Areas

    Science.gov (United States)

    Jinyu, Qi

    2008-01-01

    China's Western Development is a policy adopted to boost its less developed Western regions, that is, a systematic project and a longterm and arduous task. The development of compulsory education in China's minority areas is the key to it. This paper attempts to use the beneficial experience of developing compulsory education support system of…

  1. Policies for Compulsory Education Disparity Between Urban and Rural Areas in China

    Institute of Scientific and Technical Information of China (English)

    Bao Chuanyou

    2006-01-01

    An important function of public policies is to distribute public resources rationally.But for a long time.our public policies have been SO"city-oriented"that public resources are allocated unfairly and majority of high-quality education resources are concentrated in cities.This has already led to a serious unbalanced development in compdsory education and to a tremendous gap in conditions in schools--running and enrollment chances fur the school-age children between rural and urban areas.which tend to be enlarged.The unbalanced development in compulsory education has not only blocked the realization of public interest and equity of compulsory education but also restricted the harmonious social and economic development between urban and rural areas.It iS necessary to look into Public policies that have influence on the division of public resources and criticize them rationally.These policies include land institutions,tax systems,social security systems,policies for the input of compulsory education,and policies for teachers,etc.New policies should be made to distribute public resources fairly and rationally,narrowing the gap in compulsory education between urban and rural areas.

  2. What Is the Influence of a Compulsory Attendance Policy on Absenteeism and Performance?

    Science.gov (United States)

    Snyder, Jason L.; Lee-Partridge, Joo Eng; Jarmoszko, A. Tomasz; Petkova, Olga; D'Onofrio, Marianne J.

    2014-01-01

    The authors utilized a quasiexperimental design across sections of managerial communication and management information systems classes (N = 212) to test the impact of compulsory attendance policies on student absenteeism and performance. Students in the compulsory attendance policy condition received an attendance policy that punished excessive…

  3. Compulsory licensing in Canada and Thailand: comparing regimes to ensure legitimate use of the WTO rules.

    Science.gov (United States)

    Lybecker, Kristina M; Fowler, Elisabeth

    2009-01-01

    This paper examines two recent examples of compulsory licensing legislation: one globally embraced regime and one internationally controversial regime operating under the same WTO rules. In particular, we consider Canadian legislation and the use of compulsory licensing for HIV/AIDS drugs destined for a developing country. This is then contrasted with the conditions under which Thai authorities are pursuing compulsory licenses, the outcomes of their compulsory licenses, as well as the likely impact of the Thai policy. Finally, we construct a rubric to evaluate characteristics of a successful regime. This is used to analyze the Canadian and Thai regimes and frame the expected implications of each national policy. It is hoped that the assessment will guide changes to compulsory licensing design to ensure that legitimate regimes are embraced while illegitimate ones are disallowed.

  4. Comment on "Deep mixing of 3He: reconciling Big Bang and stellar nucleosynthesis".

    Science.gov (United States)

    Balser, Dana S; Rood, Robert T; Bania, T M

    2007-08-31

    Eggleton et al. (Reports, 8 December 2006, p. 1580) reported on a deep-mixing mechanism in low-mass stars caused by a Rayleigh-Taylor instability that destroys all of the helium isotope 3He produced during the star's lifetime. Observations of 3He in planetary nebulae, however, indicate that some stars produce prodigious amounts of 3He. This is inconsistent with the claim that all low-mass stars should destroy 3He.

  5. 49 CFR 510.3 - Compulsory process, the service thereof, claims for confidential treatment, and terms of compliance.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Compulsory process, the service thereof, claims... OF TRANSPORTATION INFORMATION GATHERING POWERS § 510.3 Compulsory process, the service thereof... description of the documents or things to be produced. (c) Service of the compulsory processes specified in...

  6. Prefabricated Vertical Drain (PVD) and Deep Cement Mixing (DCM)/Stiffened DCM (SDCM) techniques for soft ground improvement

    Science.gov (United States)

    Bergado, D. T.; Long, P. V.; Chaiyaput, S.; Balasubramaniam, A. S.

    2018-04-01

    Soft ground improvement techniques have become most practical and popular methods to increase soil strength, soil stiffness and reduce soil compressibility including the soft Bangkok clay. This paper focuses on comparative performances of prefabricated vertical drain (PVD) using surcharge, vacuum and heat preloading as well as the cement-admixed clay of Deep Cement Mixing (DCM) and Stiffened DCM (SDCM) methods. The Vacuum-PVD can increase the horizontal coefficient of consolidation, Ch, resulting in faster rate of settlement at the same magnitudes of settlement compared to Conventional PVD. Several field methods of applying vacuum preloading are also compared. Moreover, the Thermal PVD and Thermal Vacuum PVD can increase further the coefficient of horizontal consolidation, Ch, with the associated reduction of kh/ks values by reducing the drainage retardation effects in the smear zone around the PVD which resulted in faster rates of consolidation and higher magnitudes of settlements. Furthermore, the equivalent smear effect due to non-uniform consolidation is also discussed in addition to the smear due to the mechanical installation of PVDs. In addition, a new kind of reinforced deep mixing method, namely Stiffened Deep Cement Mixing (SDCM) pile is introduced to improve the flexural resistance, improve the field quality control, and prevent unexpected failures of the Deep Cement Mixing (DCM) pile. The SDCM pile consists of DCM pile reinforced with the insertion of precast reinforced concrete (RC) core. The full scale test embankment on soft clay improved by SDCM and DCM piles was also analysed. Numerical simulations using the 3D PLAXIS Foundation finite element software have been done to understand the behavior of SDCM and DCM piles. The simulation results indicated that the surface settlements decreased with increasing lengths of the RC cores, and, at lesser extent, increasing sectional areas of the RC cores in the SDCM piles. In addition, the lateral movements

  7. 16 CFR 1115.21 - Compulsory remedial actions.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Compulsory remedial actions. 1115.21 Section 1115.21 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS... Proceedings (16 CFR part 1025). (b) Injunctive relief. The Commission may apply to a U.S. district court in...

  8. Winter−spring transition in the subarctic Atlantic: microbial response to deep mixing and pre-bloom production

    DEFF Research Database (Denmark)

    Paulsen, Maria Lund; Riisgaard, Karen; Thingstad, T. Frede

    2015-01-01

    In temperate, subpolar and polar marine systems, the classical perception is that diatoms initiate the spring bloom and thereby mark the beginning of the productive season. Contrary to this view, we document an active microbial food web dominated by pico- and nanoplankton prior to the diatom bloom......, a period with excess nutrients and deep convection of the water column. During repeated visits to stations in the deep Iceland and Norwegian basins and the shallow Shetland Shelf (26 March to 29 April 2012), we investigated the succession and dynamics of photo - synthetic and heterotrophic microorganisms....... We observed that the early phytoplankton production was followed by a decrease in the carbon:nitrogen ratio of the dissolved organic matter in the deep mixed stations, an increase in heterotrophic prokaryote (bacteria) abundance and activity (indicated by the high nucleic acid:low nucleic acid...

  9. Compulsory of Malaysia’s Quality Assessment System in Construction (QLASSIC)

    Science.gov (United States)

    Manap, N.; Goh, YK; Syahrom, N.

    2017-12-01

    Nowadays, the quality in the construction industry has become very important because it contribute to the nation’s economic growth and quality of life of the house occupants. Therefore, CIDB is proposed to enforce the implementation of QLASSIC as the main element of project approval for issuance of Certificate of Fitness (CFO) or Certificate of Compliances (C.C.C) in construction industry of Malaysia. The objectives of this study are to identify the views of contractors toward the compulsory of the QLASSIC and to determine the impacts of the QLASSIC in the construction industry. The methodology used are literature review and the questionnaires. The descriptive statistic like the frequency and percentage were used for describing the respondent background. While the mean distribution analysis was used to analysis the views on the compulsory of QLASSIC and the impacts of the QLASSIC. The result of the study shows that, the views of the respondents toward the compulsory of QLASSIC and the main impacts of the QLASSIC were identified. The significance of this study is it can help contractors to understand the impacts and the important of using QLASSIC.

  10. Mixed layer depth calculation in deep convection regions in ocean numerical models

    Science.gov (United States)

    Courtois, Peggy; Hu, Xianmin; Pennelly, Clark; Spence, Paul; Myers, Paul G.

    2017-12-01

    Mixed Layer Depths (MLDs) diagnosed by conventional numerical models are generally based on a density difference with the surface (e.g., 0.01 kg.m-3). However, the temperature-salinity compensation and the lack of vertical resolution contribute to over-estimated MLD, especially in regions of deep convection. In the present work, we examined the diagnostic MLD, associated with the deep convection of the Labrador Sea Water (LSW), calculated with a simple density difference criterion. The over-estimated MLD led us to develop a new tool, based on an observational approach, to recalculate MLD from model output. We used an eddy-permitting, 1/12° regional configuration of the Nucleus for European Modelling of the Ocean (NEMO) to test and discuss our newly defined MLD. We compared our new MLD with that from observations, and we showed a major improvement with our new algorithm. To show the new MLD is not dependent on a single model and its horizontal resolution, we extended our analysis to include 1/4° eddy-permitting simulations, and simulations using the Modular Ocean Model (MOM) model.

  11. Improving deep convolutional neural networks with mixed maxout units.

    Directory of Open Access Journals (Sweden)

    Hui-Zhen Zhao

    Full Text Available Motivated by insights from the maxout-units-based deep Convolutional Neural Network (CNN that "non-maximal features are unable to deliver" and "feature mapping subspace pooling is insufficient," we present a novel mixed variant of the recently introduced maxout unit called a mixout unit. Specifically, we do so by calculating the exponential probabilities of feature mappings gained by applying different convolutional transformations over the same input and then calculating the expected values according to their exponential probabilities. Moreover, we introduce the Bernoulli distribution to balance the maximum values with the expected values of the feature mappings subspace. Finally, we design a simple model to verify the pooling ability of mixout units and a Mixout-units-based Network-in-Network (NiN model to analyze the feature learning ability of the mixout models. We argue that our proposed units improve the pooling ability and that mixout models can achieve better feature learning and classification performance.

  12. COMPULSORY EDUCATION IN ROMANIA BETWEEN EQUITY AND EFFICIENCY

    Directory of Open Access Journals (Sweden)

    Asandului Laura

    2009-05-01

    Full Text Available The paper aims at investigating the two main characteristics of a modern system of compulsory education with a focus on Romania. It assumes that the equity of the education sector and the efficiency of resource use are strongly correlated, both supporting

  13. Particle mixing processes of Chernobyl fallout in deep Norwegian Sea sediments: Evidence for seasonal effects

    Science.gov (United States)

    Balzer, W.

    1996-09-01

    A 1430 m deep station in the Norwegian Sea (Voering Plateau) was occupied five times between May 1986 and February 1987 to investigate the seasonal variation in sediment mixing rates. Cherbnbyl-derived radiocesium, identified by its high proportion of short-lived 134Cs, was used as a tracer for mixing. Most of the nuclide input arrived at the sediment within a narrow time span in June/early July during the beginning of the seasonal biogenic sedimentation pulse. Measured 137Cs profiles in the sediment over time were compared with modelled distributions calculated with a finite difference scheme. The input function of radiocesium to the sea floor was evaluated from the increase of the total inventory with time. Time-invariant mixing coefficients did not provide reasonable fits to either summer or winter distributions. The best fit was obtained with a rate of mixing proportional to the radiocesium input flux, with an average enhancement factor of 6.6 during the two summer months. It appears that the benthic macrofauna are more active during the food supply season and rapidly ingest/bury freshly sedimented materials.

  14. SU-E-T-319: Dosimetric Evaluation of IMRT with Mix-Energy Beam for Deep Seated Targets

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, S; Manigandan, D; Gandhi, A; Sharma, D; Subramani, V; Chander, S; Julkha, P [Fortis Hospital, Mohali, Punjab (India); Rath, G

    2015-06-15

    Purpose: IMRT is preferred in the range of 6–10MV X-rays. Partially adding high energy (>10MV) treatment fields, may provide advantage of both higher and lower energies. To study IMRT dose distribution obtained from treatment plans with single (6MV) and mixed-energy (6MV and 15MV) for deep seated targets (separation more than 30cm). Methods: Five patients of carcinoma of cervix were studied using eclipse planning system. Two different dynamic IMRT plans were generated for Varian CL2300C/D linear accelerator; one is by using 6MV X-ray with seven equally spaced coplanar beams. In second plan, 2 lateral oblique fields (gantry angle 102°, 255°) beam energy was modified to 15MV by keeping all other parameters and dose volume constraints constant. Dose prescription for the planning target volume (PTV) was (5040cGy/28f). For plan comparison, dose volume histogram (DVH) was used and PTV coverage index (CI=Target volume covered by prescription dose/Target volume), heterogeneity index (D5/D95), mean dose to organ at risk (OAR) and normal tissue integral dose (NTID, liter-Gray) was also noted. Total monitor unit (MU) required to deliver a plan was also noted. Results: Mixed-energy plan showed a better conformity and CI values were 0.942±0.032 and 0.960±0.040 for single-energy and mixed-energy plan, respectively. In addition, HI value of mixed energy beam is comparable to that of single energy and the values were within 1.084±0.034 and 1.082±0.032 for single energy and mixed-energy plan, respectively. Variation in mean dose to bladder, rectum and bowel were within 1.05%, 0.87% and 0.90%. NTID was lesser for mixed-energy beam due to use of two high-energy fields. NTID were 1573.40±214.60 and 1510.20±249.80 litre-Gray for single energy and mixed-energy plan. MU needed to deliver a plan was similar in both plans and MUs were 238±45 and 237±47. Conclusion: Partial use of 15MV treatment fields in IMRT plan for deep seated targets showed dosimetric advantage over 6MV

  15. 5 CFR 297.402 - Disclosure pursuant to a compulsory legal process served on the Office.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Disclosure pursuant to a compulsory legal process served on the Office. 297.402 Section 297.402 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PRIVACY PROCEDURES FOR PERSONNEL RECORDS Disclosure of Records § 297.402 Disclosure pursuant to a compulsory...

  16. The development of a collapsing method for the mixed group and point cross sections and its application on multi-dimensional deep penetration calculations

    International Nuclear Information System (INIS)

    Bor-Jing Chang; Yen-Wan H. Liu

    1992-01-01

    The HYBRID, or mixed group and point, method was developed to solve the neutron transport equation deterministically using detailed treatment at cross section minima for deep penetration calculations. Its application so far is limited to one-dimensional calculations due to the enormous computing time involved in multi-dimensional calculations. In this article, a collapsing method is developed for the mixed group and point cross section sets to provide a more direct and practical way of using the HYBRID method in the multi-dimensional calculations. A testing problem is run. The method is then applied to the calculation of a deep penetration benchmark experiment. It is observed that half of the window effect is smeared in the collapsing treatment, but it still provide a better cross section set than the VITAMIN-C cross sections for the deep penetrating calculations

  17. Fluid mixing and the deep biosphere of a fossil Lost City-type hydrothermal system at the Iberia Margin.

    Science.gov (United States)

    Klein, Frieder; Humphris, Susan E; Guo, Weifu; Schubotz, Florence; Schwarzenbach, Esther M; Orsi, William D

    2015-09-29

    Subseafloor mixing of reduced hydrothermal fluids with seawater is believed to provide the energy and substrates needed to support deep chemolithoautotrophic life in the hydrated oceanic mantle (i.e., serpentinite). However, geosphere-biosphere interactions in serpentinite-hosted subseafloor mixing zones remain poorly constrained. Here we examine fossil microbial communities and fluid mixing processes in the subseafloor of a Cretaceous Lost City-type hydrothermal system at the magma-poor passive Iberia Margin (Ocean Drilling Program Leg 149, Hole 897D). Brucite-calcite mineral assemblages precipitated from mixed fluids ca. 65 m below the Cretaceous paleo-seafloor at temperatures of 31.7 ± 4.3 °C within steep chemical gradients between weathered, carbonate-rich serpentinite breccia and serpentinite. Mixing of oxidized seawater and strongly reducing hydrothermal fluid at moderate temperatures created conditions capable of supporting microbial activity. Dense microbial colonies are fossilized in brucite-calcite veins that are strongly enriched in organic carbon (up to 0.5 wt.% of the total carbon) but depleted in (13)C (δ(13)C(TOC) = -19.4‰). We detected a combination of bacterial diether lipid biomarkers, archaeol, and archaeal tetraethers analogous to those found in carbonate chimneys at the active Lost City hydrothermal field. The exposure of mantle rocks to seawater during the breakup of Pangaea fueled chemolithoautotrophic microbial communities at the Iberia Margin, possibly before the onset of seafloor spreading. Lost City-type serpentinization systems have been discovered at midocean ridges, in forearc settings of subduction zones, and at continental margins. It appears that, wherever they occur, they can support microbial life, even in deep subseafloor environments.

  18. Compulsory Education: An Idea Whose Time Has Passed.

    Science.gov (United States)

    Sipher, Roger

    1978-01-01

    The author discusses some changes that occurred in American education from the late 1950s through the early 1970s, why these changes failed to improved the quality of education, the effect of compulsory attendance laws on educational deterioration, and what abolishing mandatory attendance would do to develop the learning environment. (RK)

  19. Stability of embankments over cement deep soil mixing columns

    International Nuclear Information System (INIS)

    Morilla Moar, P.; Melentijevic, S.

    2014-01-01

    The deep soil mixing (DSM) is one of the ground improvement methods used for the construction of embankments over soft soils. DSM column-supported embankments are constructed over soft soils to accelerate its construction, improve embankment stability, increase bearing capacity and control of total and differential settlements. There are two traditional design methods, the Japanese (rigid columns) and the scandinavian (soft and semi-rigid columns). Based on Laboratory analysis and numerical analysis these traditional approaches have been questioned by several authors due to its overestimation of the embankment stability considering that the most common failures types are not assumed. This paper presents a brief review of traditional design methods for embankments on DSM columns constructed in soft soils, studies carried out determine the most likely failure types of DSM columns, methods to decrease the overestimation when using limit equilibrium methods and numerical analysis methods that permit detect appropriate failure modes in DSM columns. Finally a case study was assessed using both limited equilibrium and finite element methods which confirmed the overestimation in the factors of safety on embankment stability over DSM columns. (Author)

  20. The Vertical Profile of Ocean Mixing

    Science.gov (United States)

    Ferrari, R. M.; Nikurashin, M.; McDougall, T. J.; Mashayek, A.

    2014-12-01

    The upwelling of bottom waters through density surfaces in the deep ocean is not possible unless the sloping nature of the sea floor is taken into account. The bottom--intensified mixing arising from interaction of internal tides and geostrophic motions with bottom topography implies that mixing is a decreasing function of height in the deep ocean. This would further imply that the diapycnal motion in the deep ocean is downward, not upwards as is required by continuity. This conundrum regarding ocean mixing and upwelling in the deep ocean will be resolved by appealing to the fact that the ocean does not have vertical side walls. Implications of the conundrum for the representation of ocean mixing in climate models will be discussed.

  1. Mixing of shallow and deep groundwater as indicated by the chemistry and age of karstic springs

    Science.gov (United States)

    Toth, David J.; Katz, Brian G.

    2006-06-01

    Large karstic springs in east-central Florida, USA were studied using multi-tracer and geochemical modeling techniques to better understand groundwater flow paths and mixing of shallow and deep groundwater. Spring water types included Ca-HCO3 (six), Na-Cl (four), and mixed (one). The evolution of water chemistry for Ca-HCO3 spring waters was modeled by reactions of rainwater with soil organic matter, calcite, and dolomite under oxic conditions. The Na-Cl and mixed-type springs were modeled by reactions of either rainwater or Upper Floridan aquifer water with soil organic matter, calcite, and dolomite under oxic conditions and mixed with varying proportions of saline Lower Floridan aquifer water, which represented 4-53% of the total spring discharge. Multiple-tracer data—chlorofluorocarbon CFC-113, tritium (3H), helium-3 (3Hetrit), sulfur hexafluoride (SF6)—for four Ca-HCO3 spring waters were consistent with binary mixing curves representing water recharged during 1980 or 1990 mixing with an older (recharged before 1940) tracer-free component. Young-water mixing fractions ranged from 0.3 to 0.7. Tracer concentration data for two Na-Cl spring waters appear to be consistent with binary mixtures of 1990 water with older water recharged in 1965 or 1975. Nitrate-N concentrations are inversely related to apparent ages of spring waters, which indicated that elevated nitrate-N concentrations were likely contributed from recent recharge.

  2. Mental health law: compulsory treatment in a general medical setting.

    Science.gov (United States)

    Linford, Steven

    2005-10-01

    Compulsory treatment of severe mental disorder can seem complicated even to psychiatrists. This article attempts to explain the current legal framework as it applies in common clinical situations in a general medical context.

  3. Pros and Cons: Compulsory 12 year education reform in Turkey

    African Journals Online (AJOL)

    By CEYLAN

    2016-05-28

    Öztürk, 2005). ... compulsory, and education following primary school (middle school, high school and university) was ...... initially very popular in the mass media in 2012, ... in Turkey: opinions and concerns of elementary.

  4. Compulsory Book Reading at School and within Leisure

    Science.gov (United States)

    Pavlovic, Slavica

    2015-01-01

    This paper deals with attitudes of secondary school pupils towards compulsory book reading at school, being the integral part of the subject Croat language and literature teaching subject, and its possible impact on their book (not-)reading in their leisure time. It is based on the research carried out through five-point Likert-type scale in…

  5. Compulsory Community Care in New Zealand Mental Health Legislation 1846-1992

    Directory of Open Access Journals (Sweden)

    Anthony John O’Brien

    2013-05-01

    Full Text Available Community treatment orders are considered a new development in mental health care and are consistent with current New Zealand mental health policy of care in the community. However, since its first adoption in 1846, New Zealand mental health legislation has always made provision for compulsory mental health care out of hospital. Analysis of the text of each of the five iterations of mental health legislation shows that an initial (1846 provision for a friend or relative to take a committed patient into his or her care, as an alternative to committal to hospital, continued though various revisions until its current expression as a community treatment order. Using Rochefort’s model of change in mental health policy, we argue that a long static period until 1911 was followed by progressive change throughout the 20th century, although provision for compulsory out-of-hospital care has been continuous over the life of New Zealand’s legislation. In the late-20th century, compulsory mental health care is tied to medical treatment and mental health service surveillance of the patient’s social circumstances. We conclude with recommendations for how reformed legislation may contribute to future mental health policy by giving effect to agendas of positive rights and social inclusion.

  6. Use of deep soil mixing as an alternate verticle barrier to slurry walls

    International Nuclear Information System (INIS)

    Miller, A.D.

    1997-01-01

    Slurry walls have become an accepted subsurface remediation technique to contain contaminated zones. However, situations develop where conventional slurry wall excavation techniques are not suitable. The use of conventional containment wall construction methods may involve removal and disposal of contaminated soils, stability concerns and the risk of open excavations. For these reasons, other installation techniques have received further consideration. Deep Soil Mixing (DSM) has emerged as a viable alternative to conventional slurry wall techniques. In situations dictating limited soil removal for contamination or stability concerns, or where space is a limitation, DSM can be used for installation of the barrier. Proper installation of a DSM wall requires sufficient monitoring and sampling to evaluate the continuity, mixing effectiveness, permeability and key into the confining layer. This paper describes a case study where DSM was used to cross major highways to avoid open excavation, and along slopes to reduce stability concerns. The DSM barrier was tied to an existing conventional slurry wall that had been installed in more stable areas without highway traffic

  7. Reframing less conventional speech to disrupt conventions of "compulsory fluency": A conversation analysis approach

    Directory of Open Access Journals (Sweden)

    Camille Duque

    2018-05-01

    Full Text Available Our purpose is to illuminate compliances with, and resistances to, what we are calling "compulsory fluency" which we define as conventions for what constitutes competent speech. We achieve our purpose through a study of day-to-day communication between a woman with less conventional speech and her support providing family members and friends. Drawing from McRuer's (2006 compulsory ablebodiedness and Kafer's (2013 compulsory able-mindedness, we use "compulsory fluency" to refer to a form of articulation that is standardized and idealized and imposed on all speakers including those whose speech is less conventional. We see compulsory fluency as central to North American conceptions of personhood which are tied to individual ability to speak for one's self (Brueggemann, 2005. In this paper, we trace some North American principles for linguistic competence to outline widely held ideals of receptive and expressive language use, namely, conventions for how language should be understood and expressed. Using Critical Disability Studies (Goodley, 2013; McRuer, 2006 together with a feminist framework of relational autonomy (Nedelsky, 1989, our goal is to focus on experiences of people with less conventional speech and draw attention to power in communication as it flows in idiosyncratic and intersubjective fashion (Mackenzie & Stoljar, 2000; Westlund, 2009. In other words, we use a critical disability and feminist framing to call attention to less conventional forms of communication competence and, in this process, we challenge assumptions about what constitutes competent speech. As part of a larger qualitative study, we conduct a conversation analysis informed by Rapley and Antaki (1996 to examine day-to-day verbal, vocal and non-verbal communications of a young woman who self identifies as "having autism" - pseudonym Addison - in interaction with her support-providing family members and friends. We illustrate a multitude of Addison's compliances with

  8. Compulsory patent licensing and local drug manufacturing capacity in Africa

    Science.gov (United States)

    2014-01-01

    Abstract Africa has the highest disease burden in the world and continues to depend on pharmaceutical imports to meet public health needs. As Asian manufacturers of generic medicines begin to operate under a more protectionist intellectual property regime, their ability to manufacture medicines at prices that are affordable to poorer countries is becoming more circumscribed. The Doha Declaration on the TRIPS Agreement and Public Health gives member states of the World Trade Organization (WTO) the right to adopt legislation permitting the use of patented material without authorization by the patent holder, a provision known as “compulsory licensing”. For African countries to take full advantage of compulsory licensing they must develop substantial local manufacturing capacity. Because building manufacturing capacity in each African country is daunting and almost illusory, an African free trade area should be developed to serve as a platform not only for the free movement of goods made pursuant to compulsory licences, but also for an economic or financial collaboration towards the development of strong pharmaceutical manufacturing capacity in the continent. Most countries in Africa are in the United Nations list of least developed countries, and this allows them, under WTO law, to refuse to grant patents for pharmaceuticals until 2021. Thus, there is a compelling need for African countries to collaborate to build strong pharmaceutical manufacturing capacity in the continent now, while the current flexibilities in international intellectual property law offer considerable benefits. PMID:24700981

  9. The impact of compulsory drug detention exposure on the avoidance of healthcare among injection drug users in Thailand.

    Science.gov (United States)

    Kerr, Thomas; Hayashi, Kanna; Ti, Lianping; Kaplan, Karyn; Suwannawong, Paisan; Wood, Evan

    2014-01-01

    Although Thailand has relied on the use of compulsory drug detention centres as a strategy to try to address problematic drug use, little is known about the effects of exposure to these centres on people who inject drugs (IDU). Therefore, we undertook this study to explore whether exposure to compulsory drug detention was associated with avoiding healthcare among Thai IDU. Using Poisson regression analyses, we examined the relationship between compulsory drug detention exposure and avoiding healthcare among participants in the Mitsampan Community Research Project based in Bangkok. 435 IDU participated in this study, including 111 (25.5%) participants who reported avoiding healthcare. In multivariate analyses, avoiding healthcare was positively associated with exposure to compulsory drug detention (adjusted prevalence ratio [APR]=1.60; 95% confidence interval [CI]: 1.16-2.21), having been refused healthcare (APR=3.46; 95% CI: 2.61-4.60), and experiencing shame associated with one's drug use (APR=1.93; 95% CI: 1.21-3.09). Exposure to compulsory drug detention was associated with avoiding healthcare among Thai IDU, suggesting that this system of detention may be contributing to the burden of preventable morbidity among IDU in this setting. Although further research is needed to confirm these findings, the results of this study reinforce previous calls to replace the system of compulsory drug detention with evidence-based public health interventions for IDU. Copyright © 2013 Elsevier B.V. All rights reserved.

  10. Constitutional Mandate for Free and Compulsory Education: New Light on the Intention of the "Founding Fathers"

    Science.gov (United States)

    Juneja, Nalini

    2015-01-01

    The original constitutional provision for free and compulsory education, granted under Article 45 stated that it was to be available for "all children until they complete the age of fourteen years", but it did not specify the lower age limit nor the stage of education (whether elementary or primary) that would be free and compulsory.…

  11. Private Property Rights and Compulsory Acquisition Process in Nigeria: the Past, Present and Future

    Directory of Open Access Journals (Sweden)

    Akintunde OTUBU

    2012-11-01

    Full Text Available Objectives: A property right is the exclusive authority to determine how a resource is used, whether that resource is owned by government or by individuals. In the context of land, it is the authority of the land owner to determine its use or otherwise. On the other hand, compulsory acquisition is the process by which government obtain land from private owners for development purposes in the best interest of the community. These diametrically opposed concepts of property rights and compulsory acquisition is reconciled with the payment of compensation for the extinguishment of private property rights. Implications: In Nigeria, these two concepts have a history of mutual conflicts, resulting in congruous resolutions most of the time, until the introduction of the Land Use Act 1978. With the coming of the Act, the pendulum has tilted in favors of compulsory acquisition to the detriment of private property rights; as compensation fails to assuage the loss occasioned by expropriation. Value: The paper explored the dichotomy between private property rights and compulsory acquisition in Nigeria in the last 50 years and submitted that the process under the Land Use Act changed the equilibrium that existed between these two concepts and produced a skewed and unfavorable result to the detriment of private property rights and National economy. It finally proposed a new equitable arrangement to the quagmire.

  12. Erratum: Mixing of shallow and deep groundwater as indicated by the chemistry and age of karstic springs

    Science.gov (United States)

    Toth, David J.; Katz, Brian G.

    2006-09-01

    Large karstic springs in east-central Florida, USA were studied using multi-tracer and geochemical modeling techniques to better understand groundwater flow paths and mixing of shallow and deep groundwater. Spring water types included Ca-HCO3 (six), Na-Cl (four), and mixed (one). The evolution of water chemistry for Ca-HCO3 spring waters was modeled by reactions of rainwater with soil organic matter, calcite, and dolomite under oxic conditions. The Na-Cl and mixed-type springs were modeled by reactions of either rainwater or Upper Floridan aquifer water with soil organic matter, calcite, and dolomite under oxic conditions and mixed with varying proportions of saline Lower Floridan aquifer water, which represented 4-53% of the total spring discharge. Multiple-tracer data—chlorofluorocarbon CFC-113, tritium (3H), helium-3 (3Hetrit), sulfur hexafluoride (SF6)—for four Ca-HCO3 spring waters were consistent with binary mixing curves representing water recharged during 1980 or 1990 mixing with an older (recharged before 1940) tracer-free component. Young-water mixing fractions ranged from 0.3 to 0.7. Tracer concentration data for two Na-Cl spring waters appear to be consistent with binary mixtures of 1990 water with older water recharged in 1965 or 1975. Nitrate-N concentrations are inversely related to apparent ages of spring waters, which indicated that elevated nitrate-N concentrations were likely contributed from recent recharge.

  13. Fixed versus mixed RSA: Explaining visual representations by fixed and mixed feature sets from shallow and deep computational models.

    Science.gov (United States)

    Khaligh-Razavi, Seyed-Mahdi; Henriksson, Linda; Kay, Kendrick; Kriegeskorte, Nikolaus

    2017-02-01

    Studies of the primate visual system have begun to test a wide range of complex computational object-vision models. Realistic models have many parameters, which in practice cannot be fitted using the limited amounts of brain-activity data typically available. Task performance optimization (e.g. using backpropagation to train neural networks) provides major constraints for fitting parameters and discovering nonlinear representational features appropriate for the task (e.g. object classification). Model representations can be compared to brain representations in terms of the representational dissimilarities they predict for an image set. This method, called representational similarity analysis (RSA), enables us to test the representational feature space as is (fixed RSA) or to fit a linear transformation that mixes the nonlinear model features so as to best explain a cortical area's representational space (mixed RSA). Like voxel/population-receptive-field modelling, mixed RSA uses a training set (different stimuli) to fit one weight per model feature and response channel (voxels here), so as to best predict the response profile across images for each response channel. We analysed response patterns elicited by natural images, which were measured with functional magnetic resonance imaging (fMRI). We found that early visual areas were best accounted for by shallow models, such as a Gabor wavelet pyramid (GWP). The GWP model performed similarly with and without mixing, suggesting that the original features already approximated the representational space, obviating the need for mixing. However, a higher ventral-stream visual representation (lateral occipital region) was best explained by the higher layers of a deep convolutional network and mixing of its feature set was essential for this model to explain the representation. We suspect that mixing was essential because the convolutional network had been trained to discriminate a set of 1000 categories, whose frequencies

  14. Compulsory treatment of 50 alcoholic drunken drivers | Ben-Aire ...

    African Journals Online (AJOL)

    Fifty alcoholic drunken drivers receiving treatment as part of a suspended sentence were studied to assess the efficacy of compulsory treatment. Twenty-six showed improvement in drinking behaviour, 12 did not co-operate and were referred back to court, 7 were re-arrested on further charges of drunken driving and 4 were ...

  15. How to Use Technology Effectively in Post-Compulsory Education

    Science.gov (United States)

    Clarke, Alan

    2011-01-01

    The use of technology within the lifelong learning sector brings many benefits to learners, teachers and managers. Aimed at trainee and practising teachers, this book contains clear, practical guidance on how to use technology and e-learning effectively to enhance all aspects of teaching and learning in the post-compulsory sector. Alan Clarke…

  16. 78 FR 78309 - Mechanical and Digital Phonorecord Delivery Compulsory License

    Science.gov (United States)

    2013-12-26

    ... time since the issuance of the NPRM, marketplace developments and changes in business models may be... and Digital Phonorecord Delivery Compulsory License AGENCY: U.S. Copyright Office, Library of Congress... locker services and purchased content locker services. Mechanical and Digital Phonorecord Delivery...

  17. Should Undergraduate Lectures be Compulsory? The Views of Dental and Medical Students from a UK University

    Directory of Open Access Journals (Sweden)

    Alaa Daud

    2017-03-01

    Full Text Available Formal lectures have been a traditional part of medical and dental education, but there is debate as to their compulsory status. This study was designed to explore dental and medical students’ views on compulsory lectures and the use of Video-Recorded Lectures (VRL. A cross-sectional study of University of Bristol students in Years 2 to 4 was conducted using an online questionnaire. The majority of both dental (76% and medical (66% students felt lectures should be non-compulsory. The most common learning resources used by both dental and medical students were live lectures, lecture handouts and VRL. The majority of both dental (84% and medical (88% students used VRL. Most students attended lectures all of the time both before and after the introduction of VRL, even though most dental and medical students believe lectures should be non-compulsory. VRL is a popular learning resource. These findings tie-in with General Dental Council and General Medical Council recommendations that encourage self-directed learning. Dental and Medical schools should offer a range of learning resources and make use of current technology, including the use of VRL.

  18. Tomographic and Geodynamic Constraints on Convection-Induced Mixing in Earth's Deep Mantle

    Science.gov (United States)

    Hafter, D. P.; Forte, A. M.; Bremner, P. M.; Glisovic, P.

    2017-12-01

    Seismological studies reveal two large low-shear-velocity provinces (LLSVPs) in the lowermost mantle (e.g., Su et al. 1994; Wang & Wen 2007; He & Wen 2012), which may represent accumulations of subducted slabs at the CMB (Tan & Gurnis 2005; Christensen & Hoffman 1994) or primordial material generated in the early differentiation of Earth (e.g. Li et al. 2014). The longevity or stability of these large-scale heterogeneities in the deep mantle depends on the vigor and spatial distribution of the convective circulation, which is in turn dependent on the distribution of mantle buoyancy and viscosity (e.g. Glisovic & Forte 2015). Here we explore the state of convective mixing in the mantle using the ASPECT convection code (Kronbichler et al. 2012). A series of experiments are conducted to consider the geochemical and dynamical contributions of LLSVPs to deep-mantle upwellings and corresponding plume-sourced volcanism. The principal feature of these experiments is the use of particle tracers to track geochemical changes in the LLSVPs and mantle plumes in addition to identifying those parts of the mantle that may remain unmixed. We employ 3-D mantle density anomalies derived from joint inversions of seismic, geodynamic and mineral physics constraints and geodynamically-constrained viscosity distributions (Glisovic et al. 2015) to ensure that the predicted flow fields yield a good match to key geophysical constraints (e.g. heat flow, global gravity anomalies and plate velocities).

  19. Establishing a compulsory drug treatment prison: Therapeutic policy, principles, and practices in addressing offender rights and rehabilitation.

    Science.gov (United States)

    Birgden, Astrid; Grant, Luke

    2010-01-01

    A Compulsory Drug Treatment Correctional Center (CDTCC) was established in Australia in 2006 for repeat drug-related male offenders. Compulsory treatment law is inconsistent with a therapeutic jurisprudence approach. Despite the compulsory law, a normative offender rehabilitation framework has been established based on offender moral rights. Within moral rights, the offender rehabilitation framework addresses the core values of freedom (supporting autonomous decision-making) and well-being (supporting support physical, social, and psychological needs). Moral rights are underpinned by a theory or principle which, in this instance, is a humane approach to offender rehabilitation. While a law that permits offenders to choose drug treatment and rehabilitation is preferable, the article discusses the establishment of a prison based on therapeutic policy, principles, and practices that respond to participants as both rights-violators and rights-holders. The opportunity for accelerated community access and a therapeutic alliance with staff has resulted in offenders actively seeking to be ordered into compulsory drug treatment and rehabilitation. Crown Copyright © 2010. Published by Elsevier Ltd. All rights reserved.

  20. Molar enthalpy of mixing and refractive indices of choline chloride-based deep eutectic solvents with water

    International Nuclear Information System (INIS)

    Ma, Chunyan; Guo, Yanhua; Li, Dongxue; Zong, Jianpeng; Ji, Xiaoyan; Liu, Chang

    2017-01-01

    Highlights: • Molar enthalpy of mixing and refractive indices for binary mixtures of different deep eutectic solvents with water. • The Redlich–Kister equation and the NRTL model was used to fit the experimental data. • The NRTL model with fitted parameters were used to predict the vapour pressure and compared with experimental data. - Abstract: The molar enthalpies of mixing were measured for binary systems of choline chloride-based deep eutectic solvents (glycerol, ethylene glycol and malonic acid) with water at 298.15 K and 308.15 K, and atmospheric pressure with an isothermal calorimeter. Refractive indices were also measured at 303.15 K and atmospheric pressure. The binary mixtures of {chcl/glycerol (1:2) + water, chcl/ethylene glycol (1:2) + water} showed exothermic behaviour over the entire range of composition, while the binary mixture of {chcl/malonic acid (1:1) + water} showed endothermic behaviour at first and then changed to be exothermic with the increasing content of chcl/malonic acid (1:1). Experimental refractive indices were fitted with the Redlich–Kister equation, and experimental molar enthalpies of mixing were correlated with the Redlich–Kister equation and the non-random two-liquid (NRTL) model. The NRTL model with the fitted parameters was used to predict the vapour pressures of these three mixtures. For mixtures of {chcl/glycerol (1:2) + water} and {chcl/ethylene glycol (1:2) + water}, the predicted vapour pressures agreed well with the experimental results from the literature. While for mixture of {chcl/malonic acid (1:1) + water}, the predicted vapour pressures showed deviation at the high concentration of chcl/malonic acid (1:1), and this was probably because of the complex molecular interaction between chcl/malonic acid (1:1) and water.

  1. What should be the moral aims of compulsory sex education?

    NARCIS (Netherlands)

    Steutel, J.W.; de Ruyter, D.J.

    2011-01-01

    With reference to the unsuccessful attempt of the Labour Government to make sex education a statutory part of the National Curriculum, this paper argues in favour of making liberal sex education compulsory at all state schools. First, the main characteristics of a liberal sex education are briefly

  2. Self-esteem of adolescents with specific language impairment as they move from compulsory education.

    Science.gov (United States)

    Lindsay, Geoff; Dockrell, Julie; Palikara, Olympia

    2010-01-01

    Children with specific language impairment (SLI) are at risk of low self-esteem during their school years. However, there is a lack of evidence of the self-esteem of young people with a history of SLI during adolescence, as they transfer from compulsory schooling to post-compulsory education, employment or training. To examine the self-esteem of young people with a history of SLI at the transition from compulsory education (16 years) to the first year of post-compulsory education, employment and training (17 years) in England. A total of 54 young people identified as having SLI at 8 years were followed up at 16 and at 17 years. The young people completed two measures of self-esteem: the Self-perception Profile for Adolescents (16 years) and the Self-perception Profile for College Students (17 years). Assessments of language, literacy and non-verbal ability were also conducted. Perceptions of scholastic competence were significantly lower than the norm at 16 years; the female students also had lower self-esteem in the social and physical appearance domains and global self-worth. However, at 17 years there were no significant differences from the norm for these self-esteem domains. There was evidence of stability within self-esteem domains over this period but also an improvement in self-perceptions of scholastic and job competence, physical appearance and athletic competence, and also global self-worth, but not the three social domains. Non-verbal cognitive ability was not correlated with any measures of self-esteem, at 16 or 17 years. Language and literacy ability, especially spelling, were correlated with scholastic and job competence at 16 years but only spelling correlated at 17 years. This study has provided evidence for improvements in self-esteem for young people with SLI after they leave school and enter the world of non-compulsory education (typically at a college), employment and training. The study has also indicated the importance of addressing self

  3. Do compulsory secondary science courses change students’ attitude towards studying science?

    DEFF Research Database (Denmark)

    Kristensen, Lærke Elisabeth; Petersen, Morten Rask

    2015-01-01

    recruitment to STEM education has been a compulsory course in the Gymnasium called Natural Science Subject (NSS). This is an interdisciplinary, introductory course with the intention that students shall “ … realize the importance of knowing and understanding natural science thinking” (Authors translation...... science and science careers. In this approach we ended up with the following research question: “Does a compulsory introductory sciences course have an impact on students’ attitude towards studying sciences in secondary school?” In this approach we chose to use parameters as motivation (Deci & Ryan, 2002...... Subject course. The distribution included all levels (K10-K12) and all study lines. Student answers were analyzed using Mann-Whitney U-test using SPSS statistics 22 as analytical tool. Comparisons for this study were made across study lines (natural science vs. human science & social science...

  4. Caregiving in first-episode psychosis: social characteristics associated with perceived 'burden' and associations with compulsory treatment.

    Science.gov (United States)

    Boydell, Jane; Onwumere, Juliana; Dutta, Rina; Bhavsar, Vishal; Hill, Nathan; Morgan, Craig; Dazzan, Paola; Morgan, Kevin; Pararajan, Madonna; Kuipers, Elizabeth; Jones, Peter; Murray, Robin; Fearon, Paul

    2014-05-01

    High incidence of psychosis and compulsory treatment within black and minority ethnic (BME) groups in the UK remain a concern. Psychosis has an impact on families and family involvement is important in predicting compulsory treatment. We therefore aimed to report the levels and predictors of caregiver burden in first-episode psychosis, in white British, and BME groups of carers, and investigate their relevance to compulsory treatment. A total of 124 caregivers were interviewed soon after the onset of psychosis using the General Health Questionnaire, GHQ-28, the Experience of Caregiving Inventory, the Personal and Psychiatric History Schedule, and the MRC Sociodemographic Schedule. The overall level of distress as measured by GHQ-28 was high (mean 50, SD 11.4). Feelings of carer burden were also high (mean total negative score 72.5, SD 34.8), increased in men, and with carer age. Neither ethnicity nor social class nor social support was associated with distress or burden. Compulsory treatment was predicted by carer burden (as indicated by carer reports of 'problems with services' (OR 1.08; 95% CI 1.01, 1.15; P = 0.023)); this was particularly evident in the black Caribbean group of carers (OR 1.28; 95% CI 1.04, 1.57; P = 0.02) CONCLUSION: Carers of adults with first-episode psychosis experience considerable psychological distress and feelings of burden. There was a specific association between carer burden, specifically in terms of experience of services, and compulsory admission of service users, particularly in the black Caribbean group. Better ways of liaising with carers and targeted efforts to reduce carer burden at illness onset are needed. © 2013 Wiley Publishing Asia Pty Ltd.

  5. Pelaksanaan Compulsory Licensing Paten Obat-obatan Bidang Farmasi di Indonesia Dikaitkan dengan Doha Declaration On The Trips Agreement And Public Health

    OpenAIRE

    Samariadi, Samariadi

    2016-01-01

    Purpose of this study is firstly to find out implementation of compulsory licensing patent medicines in Indonesia's pharmaceutical field linked Declaration DOHA, secondly to know resistance implementation of compulsory licensing to access drug in Indonesia, thirdly to know efforts should be done in implementation compulsory licensing as to support access public health. Author used legal research methods to get the result. Results of formulation problem, it can be concluded that, firstly imple...

  6. Managing "Spoiled Identities": Parents' Experiences of Compulsory Parenting Support Programmes

    Science.gov (United States)

    Holt, Amanda

    2010-01-01

    While recent years have seen a rapid growth of research exploring the usefulness of parenting support programmes, no empirical research to date has specifically explored experiences of compulsory parenting support. The present study examines the narrative accounts of 17 parents who, through a Parenting Order, were made to participate in such…

  7. Comparative analyses of compulsory school curricula in Denmark and Norway

    DEFF Research Database (Denmark)

    Rasmussen, Jens

    Tuborgvej 164 2400 København NV Denmark jera@dpu.dk The curriculum for the compulsory school is normally seen as a suitable steering and control instrument for handling the national responsibility for the content of education and also as a means to reduction of content complexity. Within the latest years...

  8. Compulsory outpatient treatment can prevent involuntary commitment

    DEFF Research Database (Denmark)

    Hansen, Lene Nørregård; Svensson, Eva Maria Birgitta; Brandt-Christensen, Anne Mette

    2014-01-01

    Compulsory outpatient treatment (co-pt) has been possible in Denmark since 2010. The aim is to secure necessary treatment, reduce involuntary commitment and improve quality of life for patients with a severe psychiatric illness. Co-pt has been brought into use in 33 cases. This case report...... describes a patient with paranoid schizophrenia who several times developed severe psychotic symptoms shortly after discharge due to lack of compliance with treatment. Within one year of co-pt the patient was not admitted to hospital and improved in overall functioning. After terminating co-pt the patient...

  9. Procedural Aspects of Compulsory Licensing Under TRIPS

    DEFF Research Database (Denmark)

    Wested, Jakob; Minssen, Timo

    2017-01-01

    and discussion addressed the framework and context for CL provided by the TRIPS convention. Both the specific requirements enshrined in TRIPS art 31 and the broader objectives and principles enshrined in TRIPS, e.g. transfer and dissemination of technology (art 7), protection of public health (art 8......In 2013, Indian authorities granted a compulsory license to NATCO Pharmaceuticals for a patented pharmaceutical product sold by Bayer. This decision raised several complex issues regarding the grant a CL and their consistency with the principles and objectives of TRIPS. Furthermore, in January 2017...

  10. Information processing style used by Compulsory Secondary Education students

    Directory of Open Access Journals (Sweden)

    Alfredo Campos

    2016-10-01

    Full Text Available Mental images are mental representations of people, objects and situations that are not present and are formed by using the imagination. Many studies have addressed this psychological ability, its typology and its involvement in the academic environment. Along these lines, the aim of our study was to assess the information processing style (verbal, object, spatial scales, and mental rotation that is commonly used by students from different specialties of Compulsory Secondary Education. To that end, two tests: The Mental Rotation Test (MRT and the Object-Spatial Imagery and Verbal Questionnaire (OSIVQ were administered to a sample of 126 Compulsory Secondary Education students. MRT assessed any significant difference in the ability to mentally rotate images depending on gender and specialty. Significant differences were found by specialty, showing that science students had better ability to mentally rotate images than humanities ones. Significant differences were found by gender and specialty in the OSIVQ. Men showed better spatial and verbal processing style than women, and humanities students excelled in object processing (in comparison to science students and in verbal processing (in comparison to science and art students.

  11. What Should Be the Moral Aims of Compulsory Sex Education?

    Science.gov (United States)

    Steutel, Jan; de Ruyter, Doret J.

    2011-01-01

    With reference to the unsuccessful attempt of the Labour Government to make sex education a statutory part of the National Curriculum, this paper argues in favour of making liberal sex education compulsory at all state schools. First, the main characteristics of a liberal sex education are briefly explained. Promoting the virtue of respect for…

  12. School Socioeconomic Context and Teacher Job Satisfaction in Japanese Compulsory Education

    Science.gov (United States)

    Matsuoka, Ryoji

    2015-01-01

    Sociologists in education have pointed out disparities associated with socioeconomic status (SES) in the Japanese compulsory education system that was once regarded as egalitarian. In addition to disparities between individual students, prior studies have empirically shown SES-based disparities among schools on important indicators such as…

  13. Leadership in Post-Compulsory Education: Inspiring Leaders of the Future

    Science.gov (United States)

    Jameson, Jill

    2005-01-01

    Based around case studies of current leaders in post-compulsory education, this book explores a number of leadership models and styles in order to provide inspiration and guidance for the next wave of potential leaders. After an introduction, the book is divided into four parts and 18 chapters. Part One contains: (1) Leadership in Post-Compulsory…

  14. Compulsory Attendance Policies: About Age or Intervention? SREB Focus Report

    Science.gov (United States)

    Grove, Jeffrey

    2014-01-01

    Over the past decade, SREB state policy-makers have focused on actions to reduce dropout rates and increase high school graduation rates. Some policy-makers have suggested that raising their state's compulsory attendance age (often called the dropout age) to require students to stay in school until age 17 or 18 is an important step. However,…

  15. Deep learning for image classification

    Science.gov (United States)

    McCoppin, Ryan; Rizki, Mateen

    2014-06-01

    This paper provides an overview of deep learning and introduces the several subfields of deep learning including a specific tutorial of convolutional neural networks. Traditional methods for learning image features are compared to deep learning techniques. In addition, we present our preliminary classification results, our basic implementation of a convolutional restricted Boltzmann machine on the Mixed National Institute of Standards and Technology database (MNIST), and we explain how to use deep learning networks to assist in our development of a robust gender classification system.

  16. A Compulsory Bioethics Module for a Large Final Year Undergraduate Class

    Science.gov (United States)

    Pearce, Roger S.

    2009-01-01

    The article describes a compulsory bioethics module delivered to [approximately] 120 biology students in their final year. The main intended learning outcome is that students should be able to analyse and reason about bioethical issues. Interactive lectures explain and illustrate bioethics. Underlying principles and example issues are used to…

  17. The indirect and direct pathways between physical fitness and academic achievement on commencement in post-compulsory education in a historical cohort of Danish school youth

    DEFF Research Database (Denmark)

    Andersen, Mikkel Porsborg; Starkof, Liis; Sessa, Maurizio

    2017-01-01

    Background: Some studies have found positive associations between physical fitness and academic achievements. Pupils' academic achievements should indicate scholastic abilities to commence a post-compulsory education. However, the effect magnitude of physical fitness and academic achievements...... on commencement in post-compulsory education is unknown. We examined the pathways between physical fitness and academic achievement on pupils' commencement in post-compulsory education. Methods: This historical cohort study followed 530 girls and 554 boys from the Danish municipality of Aalborg in the period 2008.......e., through academic achievement) OR of 1.37 (95% CI: 1.20; 1.57). Thus, 51% (95% CI: 27%; 122%) of the effect of physical fitness on post-compulsory education commencement was mediated through academic achievement. Conclusion: Physical fitness had a positive effect on post-compulsory education commencement...

  18. Comportamento à compressão de solo estabilizado com cimento utilizado em colunas de DEEP Soil Mixing

    OpenAIRE

    Geraldo Vanzolini Moretti

    2012-01-01

    Resumo: Apresenta-se neste trabalho o estudo comportamento à compressão não confinada de um solo argiloso aluvionar estabilizado segundo a metodologia Deep Soil Mixing (DSM). Esta técnica consiste no tratamento de solos moles através da mistura deste com agentes químicos estabilizantes, podendo-se utilizar cal e/ou cimento. Para a condução deste trabalho foram executadas colunas de DSM sob um aterro rodoviário localizado no nordeste do Brasil, com aproximadamente 300m de extensão. O sítio de ...

  19. Disenchantment and Participatory Limits of Compulsory Education: Lessons from Southwest China

    Science.gov (United States)

    Wu, Jinting

    2012-01-01

    Despite the state's unrelenting efforts to enforce compulsory basic education, schooling in rural ethnic China remains an elusive ideal that leads to massive dropout and prepares many only for factory sweatshops. Based on 16 months of ethnographic research, this article examines the disjuncture between the official education policy known as the…

  20. Second Chance Programmes: A Response to Educational Needs in Compulsory Education

    Science.gov (United States)

    Asin, Antonio Sanchez; Peinado, Jose Luis Boix

    2008-01-01

    This paper asks whether the integrated training provision currently offered through the different Spanish Second Chance Programmes (SCPs) constitutes a valid response to the educational needs and deficits known to exist among those young people who do not satisfactorily complete the Compulsory Secondary Education stage (ESO). The objectives of the…

  1. Childhood maltreatment and motivation for treatment in girls in compulsory residential care

    NARCIS (Netherlands)

    Leenarts, L.E.W.; Hoeve, M.; van de Ven, P.M.; Lodewijks, H.P.B.; Dorelijers, T.A.H.

    2013-01-01

    The first objective of the current study was to examine the relationship between childhood maltreatment, trauma-related symptoms and motivation for treatment in girls in compulsory residential treatment facilities. The second objective was to examine the extent to which various forms of childhood

  2. Enhancing adolescents' motivation for treatment in compulsory residential care: A clinical review

    NARCIS (Netherlands)

    Brauers, Malou; Kroneman, Leoniek; Otten, Rene; Lindauer, Ramon; Popma, Arne

    2016-01-01

    Youths in compulsory residential care show a high prevalence of various mental health problems but often lack motivation to engage in therapeutic treatment. Although the self-determination-theory (SDT) and the transtheoretical model of change (TTM) offer a useful framework for treatment motivation,

  3. "Compulsory Schooling" Despite the Law: How Education Policy Underpins the Widespread Ignorance of the Right to Home Educate in France

    Science.gov (United States)

    Bongrand, Philippe

    2016-01-01

    Everyone in France takes for granted the existence of compulsory school attendance ("école obligatoire") while home education remains very exceptional. Yet school attendance is not, and has never been, legally compulsory in France. How can one explain the fact that the right to home educate is little known and practiced? This article…

  4. Promoting Compulsory Education in Rural China: What Are the NPOs Doing?

    Science.gov (United States)

    Zhou, Huiquan

    2012-01-01

    Due to imbalanced social and economic development, education in poverty-stricken rural areas in China is lagging behind that of urban areas. The current study explores the role of the nonprofit organizations (NPOs) involved in rural compulsory education promotion. Results show that the NPOs are providing a variety of programs to promote rural…

  5. New evidence of the effects of education on health in the US: compulsory schooling laws revisited.

    Science.gov (United States)

    Fletcher, Jason M

    2015-02-01

    Estimating the effects of education on health and mortality has been the subject of intense debate and competing findings and summaries. The original Lleras-Muney (2005) methods utilizing state compulsory schooling laws as instrumental variables for completed education and US data to establish effects of education on mortality have been extended to several countries, with mixed and often null findings. However, additional US studies have lagged behind due to small samples and/or lack of mortality information in many available datasets. This paper uses a large, novel survey from the AARP on several hundred thousand respondents to present new evidence of the effects of education on a variety of health outcomes. Results suggest that education may have a role in improving several dimensions of health, such as self reports, cardiovascular outcomes, and weight outcomes. Other results appear underpowered, suggesting that further use of this methodology may require even larger, and potentially unattainable, sample sizes in the US. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. First test of WTO mechanism for procuring generic medicines under compulsory licence, via Canada's Access to Medicines Regime.

    Science.gov (United States)

    Elliott, Richard

    2007-12-01

    In July 2007, Rwanda became the first nation to initiate use of a procedure under the rules of the World Trade Organization (WTO) that is supposed to let developing countries import lower-cost, generic medicines produced in other countries under compulsory licences. And two months later, based on Rwanda's initiative, Canada's Commissioner of Patents issued the first compulsory licence under this system to permit the production of a patented AIDS drug to that country.

  7. 75 FR 32857 - Adjustment of Royalty Fee for Cable Compulsory License

    Science.gov (United States)

    2010-06-10

    ... LIBRARY OF CONGRESS Copyright Office 37 CFR Part 256 Adjustment of Royalty Fee for Cable Compulsory License CFR Correction In Title 37 of the Code of Federal Regulations, revised as of July 1, 2009, on page 666, in Sec. 256.2, make the following changes: a. In paragraph (b)(2)(i), remove ``$189,800...

  8. Voluntary vs. compulsory student evaluation of clerkships: effect on validity and potential bias.

    Science.gov (United States)

    Aoun Bahous, Sola; Salameh, Pascale; Salloum, Angelique; Salameh, Wael; Park, Yoon Soo; Tekian, Ara

    2018-01-05

    Students evaluations of their learning experiences can provide a useful source of information about clerkship effectiveness in undergraduate medical education. However, low response rates in clerkship evaluation surveys remain an important limitation. This study examined the impact of increasing response rates using a compulsory approach on validity evidence. Data included 192 responses obtained voluntarily from 49 third-year students in 2014-2015, and 171 responses obtained compulsorily from 49 students in the first six months of the consecutive year at one medical school in Lebanon. Evidence supporting internal structure and response process validity was compared between the two administration modalities. The authors also tested for potential bias introduced by the use of the compulsory approach by examining students' responses to a sham item that was added to the last survey administration. Response rates increased from 56% in the voluntary group to 100% in the compulsory group (P two consecutive years. Testing for non-response bias in the voluntary group showed that females were more frequent responders in two clerkships. Testing for authority-induced bias revealed that students might complete the evaluation randomly without attention to content. While increasing response rates is often a policy requirement aimed to improve the credibility of ratings, using authority to enforce responses may not increase reliability and can raise concerns over the meaningfulness of the evaluation. Administrators are urged to consider not only response rates, but also representativeness and quality of responses in administering evaluation surveys.

  9. A defense of compulsory vaccination.

    Science.gov (United States)

    Flanigan, Jessica

    2014-03-01

    Vaccine refusal harms and risks harming innocent bystanders. People are not entitled to harm innocents or to impose deadly risks on others, so in these cases there is nothing to be said for the right to refuse vaccination. Compulsory vaccination is therefore justified because non-vaccination can rightly be prohibited, just as other kinds of harmful and risky conduct are rightly prohibited. I develop an analogy to random gunfire to illustrate this point. Vaccine refusal, I argue, is morally similar to firing a weapon into the air and endangering innocent bystanders. By re-framing vaccine refusal as harmful and reckless conduct my aim is to shift the focus of the vaccine debate from non-vaccinators' religious and refusal rights to everyone else's rights against being infected with contagious illnesses. Religious freedom and rights of informed consent do not entitle non-vaccinators to harm innocent bystanders, and so coercive vaccination requirements are permissible for the sake of the potential victims of the anti-vaccine movement.

  10. [Certain medico-economic prerequisites for the integration of spa and resort facilities into the system of compulsory health insurance].

    Science.gov (United States)

    Artem'eva, G B; Gekht, I A

    2013-01-01

    The involvement of spa and resort facilities in the system of compulsory health insurance is of primary importance for the improvement of medical aid provided to the population. The application of the methods for the calculation of differential expenditures on the spa and resort-based treatment and estimation of their dependence on a variety of factors may facilitate the more rational use of the available resources of compulsory health insurance.

  11. Asclepius or Hippocrates? Differing Interpretations of Post-Compulsory Initial Teacher Training Mentoring

    Science.gov (United States)

    Ingleby, Ewan

    2011-01-01

    This article discusses qualitative research findings on mentoring within PCET ITT (post-compulsory education and training initial teacher training). The article complements the findings of Tedder and Lawy (2009) and Ingleby (2010). The article develops Downie and Randall's consideration of the merits or otherwise of mirroring either "Asclepius" or…

  12. Reform of the Educational Finance System as the Foundation of Compulsory Education

    Science.gov (United States)

    Suetomi, Kaori; Murray, Nadezhda

    2014-01-01

    The conditions required for a reform of the educational finance system as the foundation of compulsory education are 1) devolution to schools and introduction of national standards in order to deal with "individual equality" while compensating for the insufficiency of "aspectual equality," and 2) dealing with educational needs…

  13. 16 CFR 5.61 - Prehearing procedures; motions; interlocutory appeals; summary decision; discovery; compulsory...

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Prehearing procedures; motions; interlocutory appeals; summary decision; discovery; compulsory process. 5.61 Section 5.61 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE STANDARDS OF CONDUCT Disciplinary...

  14. Lagrangian Studies of Lateral Mixing

    Science.gov (United States)

    2017-09-19

    Final Technical 3. DATES COVERED (From - To) 01/01/2009 – 12/31/2015 4. TITLE AND SUBTITLE Lagrangian Studies of Lateral Mixing 5a. CONTRACT NUMBER...public release; distribution is unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT The Lateral Mixing Experiment (LATMIX) focused on mixing and...anomalies. LATMIX2 targeted the wintertime Gulf Stream, where deep mixed layers, strong lateral density gradients (Gulf Stream north wall) and the

  15. WTO approves TRIPS amendment on importing under compulsory licensing.

    Science.gov (United States)

    Herget, Greg

    2006-04-01

    On 6 December 2005, the World Trade Organization (WTO) amended the Trade Related Aspects of Intellectual Property Rights (TRIPS) agreement to allow WTO member states to produce, under compulsory licences, lower-cost generic pharmaceutical products for export to countries that lack domestic production capacity to make such products. The amendment makes permanent the previous decision of 30 August 2003, which has not yet proven to be an effective mechanism to encourage the supply of more affordable medicines and other pharmaceutical products to countries in need.

  16. Oltre la scuola dell’obbligo. Un’analisi empirica della decisione di proseguire nell’istruzione post-obbligatoria in Italia (Beyond Post-Compulsory Schooling: An Empirical Analysis of the Decision to Go On in Post-Compulsory Education in Italy

    Directory of Open Access Journals (Sweden)

    Massimiliano Bratti

    2001-06-01

    Full Text Available In this paper we analyse the decision to continue in post-compulsory education in Italy. Using data from the Survey of Household Income and Wealth (SHIW of the Bank of Italy we estimate binary choice models (probit and logit with the primary aim of investigating factors which affect the decision to continue in post-compulsory education. The estimates of the econometric model show that the individual with the smallest probability to continue in education has one or more of the following attributes: residence in the South, in big towns, father without formal education, self-employed or working in the agricultural sector, mother with less than high secondary schooling (licenza media superiore. The role of family income in shaping educational decisions is especially important in Central and Southern Italy, where income levels are lower. The economic variables whose role is emphasised by the mainstream approach to educational choices, the theory of human capital, turn out not to be significant in the explanation of post-compulsory schooling in Italy where social and long-term and short-term family factors appear to be dominant.

  17. Computer Science (CS) in the Compulsory Education Curriculum: Implications for Future Research

    Science.gov (United States)

    Passey, Don

    2017-01-01

    The subject of computer science (CS) and computer science education (CSE) has relatively recently arisen as a subject for inclusion within the compulsory school curriculum. Up to this present time, a major focus of technologies in the school curriculum has in many countries been on applications of existing technologies into subject practice (both…

  18. Disciplining the Conduct of Young People in Compulsory Education Policy and Practice

    Science.gov (United States)

    Hodgson, David

    2018-01-01

    Disciplining and pastoral power are central to the strategies and practices of intervening in the lives of young people deemed at risk of disengaging from school, or not completing their compulsory education. As an expression of power concerned with young people's welfare and self-improvement, disciplining and pastoral practices push young people…

  19. Struggle with School Absenteeism in Compulsory Education: Different Country Approaches and Policies

    Science.gov (United States)

    Akbasli, Sait; Sahin, Mehmet; Yilmaz, St. Pinar Mardin

    2017-01-01

    This research has been conducted to discuss the absenteeism in compulsory education and the proposed policies for reducing this problem with the school practices. In this context, the general situation regarding the absenteeism in the Turkish education system has been put forward and the current practices and policies have been addressed.…

  20. Compulsory and recommended vaccination in Italy: evaluation of coverage and non-compliance between 1998-2002 in Northern Italy.

    Science.gov (United States)

    Stampi, Serena; Ricci, Rita; Ruffilli, Isa; Zanetti, Franca

    2005-04-21

    Since vaccinations are an effective prevention tool for maintaining the health of society, the monitoring of immunization coverage allows us to identify areas where disease outbreaks are likely to occur, and possibly assist us in predicting future outbreaks. The aim of this study is the investigation of the coverage achieved for compulsory (diphtheria, tetanus, polio, hepatitis B,) and recommended (pertussis, Haemophilus influenzae, measles-mumps-rubella) vaccinations between 1998 and 2002 in the municipality of Bologna and the identification of the subjects not complying with compulsory and recommended vaccinations. The statistics regarding vaccinal coverage were elaborated from the data supplied by the Bologna vaccinal registration system (1998-2000) and the IPV4 program (2001-2002). To calculate the coverage for compulsory vaccinations and cases of non-compliance reference was made to the protocol drawn up by the Emilia Romagna Regional Administration. The reasons for non-compliance were divided into various categories In Bologna the levels of immunization for the four compulsory vaccinations are satisfactory: over 95% children completed the vaccinal cycle, receiving the booster for anti-polio foreseen in their 3rd year and for anti-diphtheria, tetanus, pertussis at 6 years. The frequency of subjects with total non-compliance (i.e. those who have not begun any compulsory vaccinations by the age of one year) is generally higher in Bologna than in the region, with a slight increase in 2002 (2.52% and 1.06% in the city and the region respectively). The frequency of the anti-measles vaccination is higher than that of mumps and rubella, which means that the single vaccine, as opposed to the combined MMR (measles-mumps-rubella) was still being used in the period in question. The most common reason for non compliance is objection of parents and is probably due to reduction of certain diseases or anxiety about the possible risks. In Bologna the frequency of children

  1. Compulsory and recommended vaccination in Italy: evaluation of coverage and non-compliance between 1998-2002 in Northern Italy

    Directory of Open Access Journals (Sweden)

    Ruffilli Isa

    2005-04-01

    Full Text Available Abstract Background Since vaccinations are an effective prevention tool for maintaining the health of society, the monitoring of immunization coverage allows us to identify areas where disease outbreaks are likely to occur, and possibly assist us in predicting future outbreaks. The aim of this study is the investigation of the coverage achieved for compulsory (diphtheria, tetanus, polio, hepatitis B, and recommended (pertussis, Haemophilus influenzae, measles-mumps-rubella vaccinations between 1998 and 2002 in the municipality of Bologna and the identification of the subjects not complying with compulsory and recommended vaccinations. Methods The statistics regarding vaccinal coverage were elaborated from the data supplied by the Bologna vaccinal registration system (1998–2000 and the IPV4 program (2001–2002. To calculate the coverage for compulsory vaccinations and cases of non-compliance reference was made to the protocol drawn up by the Emilia Romagna Regional Administration. The reasons for non-compliance were divided into various categories Results In Bologna the levels of immunization for the four compulsory vaccinations are satisfactory: over 95% children completed the vaccinal cycle, receiving the booster for anti-polio foreseen in their 3rd year and for anti-dyphteria, tetanus, pertussis at 6 years. The frequency of subjects with total non-compliance (i.e. those who have not begun any compulsory vaccinations by the age of one year is generally higher in Bologna than in the region, with a slight increase in 2002 (2.52% and 1.06% in the city and the region respectively. The frequency of the anti-measles vaccination is higher than that of mumps and rubella, which means that the single vaccine, as opposed to the combined MMR (measles-mumps-rubella was still being used in the period in question. The most common reason for non compliance is objection of parents and is probably due to reduction of certain diseases or anxiety about the

  2. Should I Take Further Mathematics? Physics Undergraduates' Experiences of Post-Compulsory Mathematics

    Science.gov (United States)

    Bowyer, Jessica; Darlington, Ellie

    2017-01-01

    It is essential that physics undergraduates are appropriately prepared for the mathematical demands of their course. This study investigated physics students' perceptions of post-compulsory mathematics as preparation for their degree course. 494 physics undergraduates responded to an online questionnaire about their experiences of A-level…

  3. Does "Compulsory Volunteering" Affect Subsequent Behavior? Evidence from a Natural Experiment in Canada

    Science.gov (United States)

    Yang, Wei

    2017-01-01

    This paper estimates the impact of "compulsory volunteerism" for adolescents on subsequent volunteer behavior exploiting the introduction of a mandatory community service program for high school (HS) students in Ontario, Canada. We use difference-in-differences approach with a large longitudinal dataset. Our estimates show that the…

  4. Compensation and Resettlement Policies after Compulsory Land Acquisition for Hydropower Development in Vietnam: Policy and Practice

    Directory of Open Access Journals (Sweden)

    Pham Huu Ty

    2013-11-01

    Full Text Available Under Vietnam’s State land ownership regime, the Government holds supreme authority over compulsory land acquisition. The results show that many improvements in land acquisition policies have been made, but poor implementation measures largely cannot prevent or even mitigate the adverse impacts on displaced persons. In particular, ineffective compensation measures and a lack of production land and livelihood alternatives accelerate the resistance of communities displaced as a result of hydropower development. The close alliance between the local government and the investor, which is considered as an “interest group”, is the main factor that leads to the ignorance of benefits of displaced people within the compulsory land acquisition process.

  5. Search for sterile neutrinos with IceCube DeepCore

    Energy Technology Data Exchange (ETDEWEB)

    Terliuk, Andrii [DESY, Platanenallee 6, 15738 Zeuthen (Germany); Collaboration: IceCube-Collaboration

    2016-07-01

    The DeepCore detector is a sub-array of the IceCube Neutrino Observatory that lowers the energy threshold for neutrino detection down to approximately 10 GeV. DeepCore is used for a variety of studies including atmospheric neutrino oscillations. The standard three-neutrino oscillation paradigm is tested using the DeepCore detector by searching for an additional light, sterile neutrino with a mass on the order of 1 eV. Sterile neutrinos do not interact with the ordinary matter, however they can be mixed with the three active neutrino states. Such mixture changes the picture of standard neutrino oscillations for atmospheric neutrinos with energies below 100 GeV. The capabilities of DeepCore detector to measure such sterile neutrino mixing will be presented in this talk.

  6. The indirect and direct pathways between physical fitness and academic achievement on commencement in post-compulsory education in a historical cohort of Danish school youth.

    Science.gov (United States)

    Andersen, Mikkel Porsborg; Starkopf, Liis; Sessa, Maurizio; Mortensen, Rikke Nørmark; Vardinghus-Nielsen, Henrik; Bøggild, Henrik; Lange, Theis; Torp-Pedersen, Christian

    2017-09-11

    Some studies have found positive associations between physical fitness and academic achievements. Pupils' academic achievements should indicate scholastic abilities to commence a post-compulsory education. However, the effect magnitude of physical fitness and academic achievements on commencement in post-compulsory education is unknown. We examined the pathways between physical fitness and academic achievement on pupils' commencement in post-compulsory education. This historical cohort study followed 530 girls and 554 boys from the Danish municipality of Aalborg in the period 2008-2014, 13 to 15 years old in 2010. Physical fitness was assessed through a watt-max cycle ergometer test represented as VO 2 max (mL·kg -1 ·min -1 ). Academic achievement, commencement status and information on covariates were obtained from Danish nationwide registers. Causal inference based mediation analysis was used to investigate the indirect and direct pathways by separating the total effect of physical fitness on post-compulsory education commencement. Adjusting for sex, age, ethnicity and socioeconomic status, the overall mediation analysis showed an odds ratio (OR) of 1.87 (95% confidence interval (CI): 1.30; 2.73) for the total effect, corresponding to an increase in odds of post-compulsory education commencement when the physical fitness was increased by 10 units of VO 2 max. The separated total effect showed a natural direct OR of 1.36 (95% CI: 0.93; 1.98) and a natural indirect (i.e., through academic achievement) OR of 1.37 (95% CI: 1.20; 1.57). Thus, 51% (95% CI: 27%; 122%) of the effect of physical fitness on post-compulsory education commencement was mediated through academic achievement. Physical fitness had a positive effect on post-compulsory education commencement. A substantial part of this effect was mediated through academic achievement.

  7. Climate, carbon cycling, and deep-ocean ecosystems.

    Science.gov (United States)

    Smith, K L; Ruhl, H A; Bett, B J; Billett, D S M; Lampitt, R S; Kaufmann, R S

    2009-11-17

    Climate variation affects surface ocean processes and the production of organic carbon, which ultimately comprises the primary food supply to the deep-sea ecosystems that occupy approximately 60% of the Earth's surface. Warming trends in atmospheric and upper ocean temperatures, attributed to anthropogenic influence, have occurred over the past four decades. Changes in upper ocean temperature influence stratification and can affect the availability of nutrients for phytoplankton production. Global warming has been predicted to intensify stratification and reduce vertical mixing. Research also suggests that such reduced mixing will enhance variability in primary production and carbon export flux to the deep sea. The dependence of deep-sea communities on surface water production has raised important questions about how climate change will affect carbon cycling and deep-ocean ecosystem function. Recently, unprecedented time-series studies conducted over the past two decades in the North Pacific and the North Atlantic at >4,000-m depth have revealed unexpectedly large changes in deep-ocean ecosystems significantly correlated to climate-driven changes in the surface ocean that can impact the global carbon cycle. Climate-driven variation affects oceanic communities from surface waters to the much-overlooked deep sea and will have impacts on the global carbon cycle. Data from these two widely separated areas of the deep ocean provide compelling evidence that changes in climate can readily influence deep-sea processes. However, the limited geographic coverage of these existing time-series studies stresses the importance of developing a more global effort to monitor deep-sea ecosystems under modern conditions of rapidly changing climate.

  8. Some Remarks on Practical Aspects of Laboratory Testing of Deep Soil Mixing Composites Achieved in Organic Soils

    Science.gov (United States)

    Kanty, Piotr; Rybak, Jarosław; Stefaniuk, Damian

    2017-10-01

    This paper presents the results of laboratory testing of organic soil-cement samples are presented in the paper. The research program continues previously reported the authors’ experiences with cement-fly ash-soil sample testing. Over 100 of compression and a dozen of tension tests have been carried out altogether. Several samples were waiting for failure test for over one year after they were formed. Several factors, like: the large amount of the tested samples, a long observation time, carrying out the tests in complex cycles of loading and the possibility of registering the loads and deformation in the axial and lateral direction - have made it possible to take into consideration numerous interdependencies, three of which have been presented in this work: the increments of compression strength, the stiffness of soil-cement in relation to strength and the tensile strength. Compressive strength, elastic modulus and tensile resistance of cubic samples were examined. Samples were mixed and stored in the laboratory conditions. Further numerical analysis in the Finite Element Method numerical code Z_Soil, were performed on the basis of laboratory test results. Computations prove that cement-based stabilization of organic soil brings serious risks (in terms of material capacity and stiffness) and Deep Soil Mixing technology should not be recommended for achieving it. The numerical analysis presented in the study below includes only one type of organic and sandy soil and several possible geometric combinations. Despite that, it clearly points to the fact that designing the DSM columns in the organic soil may be linked with a considerable risk and the settlement may reach too high values. During in situ mixing, the organic material surrounded by sand layers surely mixes with one another in certain areas. However, it has not been examined and it is difficult to assume such mixing already at the designing stage. In case of designing the DSM columns which goes through a

  9. Oltre la scuola dell’obbligo. Un’analisi empirica della decisione di proseguire nell’istruzione post-obbligatoria in Italia (Beyond Post-Compulsory Schooling: An Empirical Analysis of the Decision to Go On in Post-Compulsory Education in Italy

    Directory of Open Access Journals (Sweden)

    Massimiliano Bratti

    2012-04-01

    Full Text Available In this paper we analyse the decision to continue in post-compulsory education in Italy. Using data from the Survey of Household Income and Wealth (SHIW of the Bank of Italy we estimate binary choice models (probit and logit with the primary aim of investigating factors which affect the decision to continue in post-compulsory education. The estimates of the econometric model show that the individual with the smallest probability to continue in education has one or more of the following attributes: residence in the South, in big towns, father without formal education, self-employed or working in the agricultural sector, mother with less than high secondary schooling (licenza media superiore. The role of family income in shaping educational decisions is especially important in Central and Southern Italy, where income levels are lower. The economic variables whose role is emphasised by the mainstream approach to educational choices, the theory of human capital, turn out not to be significant in the explanation of post-compulsory schooling in Italy where social and long-term and short-term family factors appear to be dominant.          JEL Codes: I21, I28Keywords: Education, Schooling

  10. Focus on Formative Feedback communication and self-regulated learning – a study in compulsory schools

    DEFF Research Database (Denmark)

    Kirkegaard, Preben Olund

    This study addresses the conceptual challenge of providing students in compulsory schools with good quality formative feedback to enhance self-regulated learning in social interactions. Resent educational research indicates that social communicative interactions in the classroom, with a focus...... qualitative data from video recorded teaching sessions and student group interviews. Methodologically we are inspired by the ethnographical classroom research method. The empirical basis for studying these aspects is data from two compulsory schools in Denmark. This study is a work in progress. Our findings...... on formative feedback, hold the potential to enhance students learning. Self-regulated learning is highly pertinent and can be seen as one of the most import skills for the 21st century learner. We argue that formative feedbackcommunication in interactions is crucial for students to develop self...

  11. An Idiographic Analysis of Amotivation in Compulsory School Physical Education

    OpenAIRE

    Ntoumanis, Nikos; Pensgaard, Anne-Marte; Martin, Chris; Pipe, Katie

    2004-01-01

    The purpose of this study was to provide an in-depth account of amotivation in compulsory school physical education by examining its major causes, the way it is displayed, and how it can be tackled. From an initial participant pool of 390 British schoolchildren ages 14 to 15 years, 21 of them (15 girls and 6 boys) were selected to participate in semi-structured interviews. They were categorized as being amotivated based on their responses to a questionnaire measuring motivation in physical ed...

  12. Turkish Compulsory Earthquake Insurance and "Istanbul Earthquake

    Science.gov (United States)

    Durukal, E.; Sesetyan, K.; Erdik, M.

    2009-04-01

    The city of Istanbul will likely experience substantial direct and indirect losses as a result of a future large (M=7+) earthquake with an annual probability of occurrence of about 2%. This paper dwells on the expected building losses in terms of probable maximum and average annualized losses and discusses the results from the perspective of the compulsory earthquake insurance scheme operational in the country. The TCIP system is essentially designed to operate in Turkey with sufficient penetration to enable the accumulation of funds in the pool. Today, with only 20% national penetration, and about approximately one-half of all policies in highly earthquake prone areas (one-third in Istanbul) the system exhibits signs of adverse selection, inadequate premium structure and insufficient funding. Our findings indicate that the national compulsory earthquake insurance pool in Turkey will face difficulties in covering incurring building losses in Istanbul in the occurrence of a large earthquake. The annualized earthquake losses in Istanbul are between 140-300 million. Even if we assume that the deductible is raised to 15%, the earthquake losses that need to be paid after a large earthquake in Istanbul will be at about 2.5 Billion, somewhat above the current capacity of the TCIP. Thus, a modification to the system for the insured in Istanbul (or Marmara region) is necessary. This may mean an increase in the premia and deductible rates, purchase of larger re-insurance covers and development of a claim processing system. Also, to avoid adverse selection, the penetration rates elsewhere in Turkey need to be increased substantially. A better model would be introduction of parametric insurance for Istanbul. By such a model the losses will not be indemnified, however will be directly calculated on the basis of indexed ground motion levels and damages. The immediate improvement of a parametric insurance model over the existing one will be the elimination of the claim processing

  13. Does school time matter? On the impact of compulsory education age on school dropout

    NARCIS (Netherlands)

    Cabus, S.J.; de Witte, K.

    2010-01-01

    A straightforward way to prevent students from leaving education without a higher secondary diploma consists of increasing the compulsory education age. By staying longer in school, the idea is that more students eventually obtain a higher secondary diploma. This paper examines by a

  14. Mobile Phone Voting for Participation and Engagement in a Large Compulsory Law Course

    Science.gov (United States)

    Habel, Chad; Stubbs, Matthew

    2014-01-01

    This article reports on an action-research project designed to investigate the effect of a technological intervention on the complex interactions between student engagement, participation, attendance and preparation in a large lecture delivered as part of a compulsory first-year law course, a discipline which has not been the focus of any previous…

  15. Engineering characteristics of the improved soil by deep mixing method using coal ash; Sekitanbai wo riyoshita FGC shinso kongo shori koho ni yoru kairyodo no kogakuteki seishitsu to kongo no tenbo ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, T [Center for Coal Utilization, Japan, Tokyo (Japan); Azuma, K; Watanabe, M [Electric Power Development Co. Ltd., Tokyo (Japan)

    1996-09-01

    Japan currently produces about six million tons of coal ash annually, whose effective bulk utilization to earth engineering materials is an important issue of technological development. A slurry may be made by mixing the following three kinds of materials: fly ash discharged from power plants exclusively burning dust coal (F), gypsum generated as a by-product in a stack gas desulfurizing process (G), and commercially available cement (C). The slurry would be called an FGC slurry taking the first letters of the materials. This paper presents the results of laboratory tests, in-situ execution tests and centrifuge model testing on engineering characteristics of soils improved by the FGC slurry when the slurry is applied to implementing the deep mixing method. As a result, a large number of findings were obtained including the following matters: the FGC deep mixing method makes it possible to improve ground beds having small deformation coefficient with the same accuracy as in the cement-based deep mixing (CDM) method at strengths lower than 5 kg/cm {sup 2} which is difficult with the CDM method, not to speak of strengths equivalent to that is possible with the normal CDM method; and development of a ground bed with improved strength is possible without being governed by quality and kinds of the fly ash. 1 ref., 23 figs., 5 tabs.

  16. Ethnic variations in pathways to acute care and compulsory detention for women experiencing a mental health crisis.

    Science.gov (United States)

    Lawlor, Caroline; Johnson, Sonia; Cole, Laura; Howard, Louise M

    2012-01-01

    Much recent debate on excess rates of compulsory detention and coercive routes to care has focused on young black men; evidence is less clear regarding ethnic variations among women and factors that may mediate these. To explore ethnic variations in compulsory detentions of women, and to explore the potential role of immediate pathways to admission and clinician-rated reasons for admission as mediators of these differences. All women admitted to an acute psychiatric inpatient ward or a women's crisis house in four London boroughs during a 12-week period were included. Data were collected regarding their pathways to care, clinician-rated reasons for admission, hospital stays, and social and clinical characteristics. Two hundred and eighty seven (287) women from white British, white other, black Caribbean, black African and black other groups were included. Adjusting for social and clinical characteristics, all groups of black patients and white other patients were significantly more likely to have been compulsorily admitted than white British patients; white British patients were more likely than other groups to be admitted to a crisis house and more likely than all the black groups to be admitted because of perceived suicide risk. Immediate pathways to care differed: white other, black African and black other groups were less likely to have referred themselves in a crisis and more likely to have been in contact with the police. When adjustment was made for differences in pathways to care, the ethnic differences in compulsory admission were considerably reduced. There are marked ethnic inequities not only between white British and black women, but also between white British and white other women in experiences of acute admission. Differences between groups in help-seeking behaviours in a crisis may contribute to explaining differences in rates of compulsory admission.

  17. Compulsory Disclosure by Newsmen: The Implications of the Legal Heritage for the Contemporary Situation.

    Science.gov (United States)

    Eshelman, David

    In the almost 100 years of reported litigation pertaining to compulsory disclosure of news sources, the basic pleadings asserted in common law cases have included employer's regulations, professional ethics, self-incrimination, lack of jurisdictional authority, and relevancy. American courts have consistently denied an evidentiary privilege for…

  18. Computer Science Education in Secondary Schools--The Introduction of a New Compulsory Subject

    Science.gov (United States)

    Hubwieser, Peter

    2012-01-01

    In 2004 the German state of Bavaria introduced a new compulsory subject of computer science (CS) in its grammar schools ("Gymnasium"). The subject is based on a comprehensive teaching concept that was developed by the author and his colleagues during the years 1995-2000. It comprises mandatory courses in grades 6/7 for all students of…

  19. The Unified Patent Court (UPC), Compulsory Licensing and Competition Law

    DEFF Research Database (Denmark)

    Petersen, Clement Salung; Riis, Thomas; Schovsbo, Jens Hemmingsen

    2014-01-01

    Competition law and rules on compulsory licensing are considered as indispensable instruments to balance patent rights. In this article, we examine the room for using such balancing instruments in the context of the UPC. We analyse whether the balancing instruments will remain applicable...... that the UPC is likely to be less inclined to use them. To redress that problem we suggest that the UPC acknowledges the institutional biases of the court and looks for ways to include other values and interests than the proprietary values and interests of patent law....

  20. Preventing compulsory admission to psychiatric inpatient care through psycho-education and crisis focused monitoring.

    Science.gov (United States)

    Lay, Barbara; Salize, Hans Joachim; Dressing, Harald; Rüsch, Nicolas; Schönenberger, Thekla; Bühlmann, Monika; Bleiker, Marco; Lengler, Silke; Korinth, Lena; Rössler, Wulf

    2012-09-05

    The high number of involuntary placements of people with mental disorders in Switzerland and other European countries constitutes a major public health issue. In view of the ethical and personal relevance of compulsory admission for the patients concerned and given the far-reaching effects in terms of health care costs, innovative interventions to improve the current situation are much needed. A number of promising approaches to prevent involuntary placements have been proposed that target continuity of care by increasing self-management skills of patients. However, the effectiveness of such interventions in terms of more robust criteria (e.g., admission rates) has not been sufficiently analysed in larger study samples. The current study aims to evaluate an intervention programme for patients at high risk of compulsory admission to psychiatric hospitals. Effectiveness will be assessed in terms of a reduced number of psychiatric hospitalisations and days of inpatient care in connection with involuntary psychiatric admissions as well as in terms of cost-containment in inpatient mental health care. The intervention furthermore intends to reduce the degree of patients' perceived coercion and to increase patient satisfaction, their quality of life and empowerment. This paper describes the design of a randomised controlled intervention study conducted currently at four psychiatric hospitals in the Canton of Zurich. The intervention programme consists of individualised psycho-education focusing on behaviours prior to and during illness-related crisis, the distribution of a crisis card and, after inpatient admission, a 24-month preventive monitoring of individual risk factors for compulsory re-admission to hospital. All measures are provided by a mental health care worker who maintains permanent contact to the patient over the course of the study. In order to prove its effectiveness the intervention programme will be compared with standard care procedures (control group

  1. Preventing compulsory admission to psychiatric inpatient care through psycho-education and crisis focused monitoring

    Directory of Open Access Journals (Sweden)

    Lay Barbara

    2012-09-01

    Full Text Available Abstract Background The high number of involuntary placements of people with mental disorders in Switzerland and other European countries constitutes a major public health issue. In view of the ethical and personal relevance of compulsory admission for the patients concerned and given the far-reaching effects in terms of health care costs, innovative interventions to improve the current situation are much needed. A number of promising approaches to prevent involuntary placements have been proposed that target continuity of care by increasing self-management skills of patients. However, the effectiveness of such interventions in terms of more robust criteria (e.g., admission rates has not been sufficiently analysed in larger study samples. The current study aims to evaluate an intervention programme for patients at high risk of compulsory admission to psychiatric hospitals. Effectiveness will be assessed in terms of a reduced number of psychiatric hospitalisations and days of inpatient care in connection with involuntary psychiatric admissions as well as in terms of cost-containment in inpatient mental health care. The intervention furthermore intends to reduce the degree of patients’ perceived coercion and to increase patient satisfaction, their quality of life and empowerment. Methods/Design This paper describes the design of a randomised controlled intervention study conducted currently at four psychiatric hospitals in the Canton of Zurich. The intervention programme consists of individualised psycho-education focusing on behaviours prior to and during illness-related crisis, the distribution of a crisis card and, after inpatient admission, a 24-month preventive monitoring of individual risk factors for compulsory re-admission to hospital. All measures are provided by a mental health care worker who maintains permanent contact to the patient over the course of the study. In order to prove its effectiveness the intervention programme will be

  2. Visa refusal following compulsory hospital admission under the Mental Health Act 1983 (England and Wales): fact or fiction?

    Science.gov (United States)

    Ashmore, R

    2015-08-01

    Historically, compulsory hospital admission led to discrimination for service users. For example, until recently detention under the Mental Health Act 1983 (England and Wales) would disqualify a person from being a Member of Parliament. There is a belief among mental health professionals that compulsory hospital admission will result in service users being refused a tourist visa. However, there is a paucity of literature on this topic, particularly from an international perspective. Based on the information reviewed in this study, there is no evidence to support this belief. Of 262 travel destinations, 96 (36.6%) require British citizens to obtain a tourist visa. Six (2.3%) destinations require applicants to declare a mental health condition in order to obtain a tourist visa. None of these destinations ask applicants to declare a history of compulsory hospital admission. However, the possibility exists that anyone declaring a mental health problem may be asked to provide further information about their condition before a visa is granted. Mental health nurses require education to ensure that their knowledge of mental health legislation is up to date. This education should include information on the potential consequences of compulsory hospital admission for the service user's social life following discharge. Service users and their families should be provided with written information on the potential social impact of detention along with a list of organizations that can provide advice on specific issues. This study sought to establish whether a history of compulsory hospital admission prevented a person from obtaining a tourist visa. A visa application form and/or other relevant information were obtained for 262 travel destinations visited by British citizens. Ninety-six (36.6%) destinations require British citizens to obtain a tourist visa. All visas are issued subject to travellers meeting a number of conditions, for example being in possession of travel insurance

  3. 76 FR 590 - Adjustment or Determination of Compulsory License Rates for Making and Distributing Phonorecords

    Science.gov (United States)

    2011-01-05

    ... $150 filing fee, must be addressed to: Copyright Royalty Board, P.O. Box 70977, Washington, DC 20024... LIBRARY OF CONGRESS Copyright Royalty Board [Docket No. 2011-3 CRB Phonorecords II] Adjustment or Determination of Compulsory License Rates for Making and Distributing Phonorecords AGENCY: Copyright Royalty...

  4. 38 CFR 1.468 - Relationship to Federal statutes protecting research subjects against compulsory disclosure of...

    Science.gov (United States)

    2010-07-01

    ... Information from Department of Veterans Affairs (va) Records Relating to Drug Abuse, Alcoholism Or Alcohol... on the Attorney General, respectively, the power to authorize researchers conducting certain types of... statutes protecting research subjects against compulsory disclosure of their identity. 1.468 Section 1.468...

  5. 77 FR 34211 - Modification of Multiple Compulsory Reporting Points; Continental United States, Alaska and Hawaii

    Science.gov (United States)

    2012-06-11

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2012-0130; Airspace Docket No. 12-AWA-2] RIN 2120-AA66 Modification of Multiple Compulsory Reporting Points; Continental United States, Alaska and Hawaii AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final...

  6. Compulsory teaching of occupational health: impact on attitude of medical students in Brazil and Germany

    NARCIS (Netherlands)

    Russ, Paul; Strümpell, Stephanie; Carvalho, Denise; Zander, Sabrina; Smits, Paul; Nowak, Dennis; Radon, Katja

    2012-01-01

    Purpose To assess medical students' attitude toward occupational health (OH) in Brazil and Germany before and after a compulsory OH course. Methods A questionnaire regarding the attitude toward OH was completed by medical students at the beginning of the OH teaching term at the Federal University of

  7. Conscription in the Afghan Army. Compulsory Service Versus an All Volunteer Force

    Science.gov (United States)

    2011-04-01

    580 in 2004) to avoid compulsory service. Dual citizens and only sons or breadwinners are exempted. There appears to be substantial corruption in...their Soviet advisors. There were many reports of conscripts showing up for training just long enough to be issued So- viet-made weapons and...create a national ID card program and a census, as well as other initiatives to collect information on the popula- tion - but these programs are just

  8. Prosocial behavior and self-concept of Spanish students of Compulsory Secondary Education

    OpenAIRE

    Inglés, Cándido J.; Martínez-González, Agustín Ernesto; García-Fernández, José Manuel; Torregrosa, María S.; Ruiz Esteban, Cecilia

    2012-01-01

    This study analyzed the relationship between prosocial behavior and self-concept dimensions in a sample of 2022 Spanish students (51.1% males) of Compulsory Secondary Education. The prosocial behavior was measured with the Prosocial Behavior scale of the Teenage Inventory of Social Skills (TISS) and the self-concept was measured with the Self-Description Questionnaire-II (SDQ-II). Logistic regression analyses revealed that prosocial behavior is a positive and significant statistically predict...

  9. Compulsory creativity – a critique of cognitive capitalism

    DEFF Research Database (Denmark)

    Larsen, Steen Nepper

    2014-01-01

    Contemporary capitalism can be labelled cognitive capitalism. In this dynamic, demanding and extremely transformative mode of production, knowledge becomes a strategic force of production and an important commodity, while concepts and ideas become items. This article sheds light on some...... of the implications of the emergence of a cognitive capitalism. In response to modern oxymorons, such as compulsory creativity and mandatory originality, this article offers various attempts to interpret and criticise how human inventiveness and a whole range of externalities get attuned to economic and market...... strategies, depriving them their natural, social and individual qualities. The aim of this article is to renew and sharpen a critique of the new type of capitalism and to foster some normative bricks that might be able to inspire alternative ways of thinking and living. Keywords: Cognitive capitalism...

  10. Measuring the Long-Term Effectiveness of a Compulsory Approach to Behaviour Change: Analysis of the "Say No to Plastic Bag" Campaign at the Universiti Sains Malaysia

    Science.gov (United States)

    Mustafa, Hasrina; Yusoff, Ronzi Mohd

    2011-01-01

    This research looked into the effectiveness of a campaign at the Universiti Sains Malaysia for a compulsory ban on disposable plastics. Although there was high awareness of the "Say No to Plastic Bags" bags campaign, and moderate compliance on campus, we wondered whether a compulsory approach would maintain the desired behaviours off…

  11. When Learning English is Compulsory at School:

    Directory of Open Access Journals (Sweden)

    Maryam Azarnoosh

    2014-11-01

    Full Text Available Research findings highlight the role of motivation in the long-term process of learning a second/foreign language. One’s motivation can change even in a short period of time under the influence of multifarious factors. To enrich our understanding of the attitudinal/motivational basis of foreign language learning this study attempts to investigate L2 motivational fluctuation, and the possibility of predicting EFL learners’ motivated learning behavior in light of Dörnyei’s (2005, 2009 theory of L2 motivational self system. To this end, 1670 junior high and high school students studying English as a compulsory subject in Iran filled out L2 motivational self system questionnaire. Independent samples t-test and regression analyses were applied; and the findings indicated a higher motivational disposition for junior high school students in comparison to high school students, except for their attitudes towards L2 community. For both groups, attitudes towards L2 learning was the best predictor of students motivated learning behavior.

  12. Does deep ocean mixing drive upwelling or downwelling of abyssal waters?

    Science.gov (United States)

    Ferrari, R. M.; McDougall, T. J.; Mashayek, A.; Nikurashin, M.; Campin, J. M.

    2016-02-01

    It is generally understood that small-scale mixing, such as is caused by breaking internal waves, drives upwelling of the densest ocean waters that sink to the ocean bottom at high latitudes. However the observational evidence that the turbulent fluxes generated by small-scale mixing in the stratified ocean interior are more vigorous close to the ocean bottom than above implies that small-scale mixing converts light waters into denser ones, thus driving a net sinking of abyssal water. Using a combination of numerical models and observations, it will be shown that abyssal waters return to the surface along weakly stratified boundary layers, where the small-scale mixing of density decays to zero. The net ocean meridional overturning circulation is thus the small residual of a large sinking of waters, driven by small-scale mixing in the stratified interior, and a comparably large upwelling, driven by the reduced small-scale mixing along the ocean boundaries.

  13. The Ideology of Innovation Education and Its Emergence as a New Subject in Compulsory Schools

    Science.gov (United States)

    Jonsdottir, Svanborg R.; Thorsteinsson, Gisli; Page, Tom

    2008-01-01

    Innovation Education and Practical Use of Knowledge was introduced into the Icelandic National Curriculum for compulsory schools in 1999, where it is defined by the curriculum writers as a "school subject" but is not allocated any direct time in the recommended guidelines for subjects. This paper describes a master's research project…

  14. The indirect and direct pathways between physical fitness and academic achievement on commencement in post-compulsory education in a historical cohort of Danish school youth

    DEFF Research Database (Denmark)

    Andersen, Mikkel Porsborg; Starkopf, Liis; Sessa, Maurizio

    2017-01-01

    Background: Some studies have found positive associations between physical fitness and academic achievements. Pupils' academic achievements should indicate scholastic abilities to commence a post-compulsory education. However, the effect magnitude of physical fitness and academic achievements...... on commencement in post-compulsory education is unknown. We examined the pathways between physical fitness and academic achievement on pupils' commencement in post-compulsory education. Methods: This historical cohort study followed 530 girls and 554 boys from the Danish municipality of Aalborg in the period 2008......-2014, 13 to 15 years old in 2010. Physical fitness was assessed through a watt-max cycle ergometer test represented as VO2max (mL·kg-1·min-1). Academic achievement, commencement status and information on covariates were obtained from Danish nationwide registers. Causal inference based mediation analysis...

  15. Using the Theory of Planned Behaviour to Understand Students' Subject Choices in Post-Compulsory Education

    Science.gov (United States)

    Taylor, Rachel Charlotte

    2015-01-01

    In recent years, there have been concerns in the UK regarding the uptake of particular subjects in post-compulsory education. Whilst entries for Advanced level (A-level) subjects such as media studies have experienced considerable growth, entries for A-level physics have, until recently, been declining, prompting fears of a skills crisis in future…

  16. [Potentials and limitations of the planned compulsory quality assurance program for cataract surgery (Qesü)].

    Science.gov (United States)

    Hahn, U; Bertram, B; Krummenauer, F; Reuscher, A; Fabian, E; Neuhann, T; Schmickler, S; Neuhann, I

    2013-04-01

    Cataract surgery is scheduled for a federal program for quality improvement across the different sectors of care (outpatient care and hospitals). In case of implementation not only ophthalmic surgeons but all ophthalmologists would have to contribute to the documentation. Urgency, potential benefits and limitations of a compulsory compared to a voluntary quality assessment system are analyzed.

  17. On the Brink of Education: Experiences of Refugees beyond the Age of Compulsory Education in Austria

    Science.gov (United States)

    Atanasoska, Tatjana; Proyer, Michelle

    2018-01-01

    This paper offers first-hand accounts of refugees beyond the age of compulsory education having arrived in Austria during the last five years. Their accounts were collected using qualitative interviews and a visual method to allow for different approaches towards their educational biographies. Nine individual and two group interviews (altogether…

  18. Preventing compulsory admission to psychiatric inpatient care: Perceived coercion, empowerment and self-reported mental health functioning after 12 months of preventive monitoring

    Directory of Open Access Journals (Sweden)

    Barbara eLay

    2015-11-01

    Full Text Available Objective: To evaluate effects of a preventive monitoring program targeted to reduce compulsory re-hospitalization and perceived coercion in patients with severe mental disorder. We analyze patient outcomes in terms of perceived coercion, empowerment and self-reported mental health functioning at 12 months. Methods: The program consists of individualized psycho-education, crisis cards and, after discharge from the psychiatric hospital, a 24-month preventive monitoring. In total, 238 psychiatric inpatients who had had compulsory admission(s during the past 24 months were included in the trial. T1-assessment 12 months after baseline was achieved for 182 patients. Results: Study participants reported lower levels of perceived coercion, negative pressures and process exclusion, a higher level of optimism, and a lesser degree of distress due to symptoms, interpersonal relations and social role functioning (significant time effects. However, improvements were not confined to the intervention group, but seen also in the TAU group (no significant group or interaction effects. Altered perceptions were linked to older age, shorter illness duration, female sex, non-psychotic disorder, and compulsory hospitalization not due to risk of harm to others. Conclusion: Our findings suggest that changes in the subjective perspective were fuelled primarily by participation in this study, rather than by having received the specific intervention. The study contributes to a better understanding of the interaction between 'objective' measures (compulsory readmissions and patients’ perceptions and highlights the need for treatment approaches promoting empowerment in individuals with a history of involuntary psychiatric hospitalizations.

  19. DEEP MIXING IN EVOLVED STARS. II. INTERPRETING Li ABUNDANCES IN RED GIANT BRANCH AND ASYMPTOTIC GIANT BRANCH STARS

    International Nuclear Information System (INIS)

    Palmerini, S.; Busso, M.; Maiorca, E.; Cristallo, S.; Abia, C.; Uttenthaler, S.; Gialanella, L.

    2011-01-01

    We reanalyze the problem of Li abundances in red giants of nearly solar metallicity. After outlining the problems affecting our knowledge of the Li content in low-mass stars (M ≤ 3 M sun ), we discuss deep-mixing models for the red giant branch stages suitable to account for the observed trends and for the correlated variations of the carbon isotope ratio; we find that Li destruction in these phases is limited to masses below about 2.3 M sun . Subsequently, we concentrate on the final stages of evolution for both O-rich and C-rich asymptotic giant branch (AGB) stars. Here, the constraints on extra-mixing phenomena previously derived from heavier nuclei (from C to Al), coupled to recent updates in stellar structure models (including both the input physics and the set of reaction rates used), are suitable to account for the observations of Li abundances below A(Li) ≡ log ε(Li) ≅ 1.5 (and sometimes more). Also, their relations with other nucleosynthesis signatures of AGB phases (like the abundance of F, and the C/O and 12 C/ 13 C ratios) can be explained. This requires generally moderate efficiencies (M-dot -6 M sun yr -1 ) for non-convective mass transport. At such rates, slow extra mixing does not remarkably modify Li abundances in early AGB phases; on the other hand, faster mixing encounters a physical limit in destroying Li, set by the mixing velocity. Beyond this limit, Li starts to be produced; therefore, its destruction on the AGB is modest. Li is then significantly produced by the third dredge up. We also show that effective circulation episodes, while not destroying Li, would easily bring the 12 C/ 13 C ratios to equilibrium, contrary to the evidence in most AGB stars, and would burn F beyond the limits shown by C(N) giants. Hence, we do not confirm the common idea that efficient extra mixing drastically reduces the Li content of C stars with respect to K-M giants. This misleading appearance is induced by biases in the data, namely: (1) the difficulty

  20. Communication subjective assessments of patients undergoing compulsory treatment with the severity of negative symptoms and cognitive functioning level

    Directory of Open Access Journals (Sweden)

    Kabanov T.N.

    2015-04-01

    Full Text Available The article presents the results of studies on the relationship of subjective assessments of the mentally ill with the severity of negative symptoms and cognitive functioning level. The features of patients perception of various aspects of compulsory treatment and subjective satisfaction with treatment. In a study of 94 male patients with a diagnosis of organic mental disorder and schizophrenia was used diagnostic system, consisting of patopsihologicheskogo study, formal survey map, the scale of assessment of negative symptoms SANS, questionnaire symptom levels SCL-90, self-existing problems, as well as - in Test authoring tool sheet to treatment and hospital stay (VG Bulygin, Kabanov, TN, 2011. The differences in subjective assessments of aspects of compulsory treatment and social functioning of patients with varying degrees of severity of negative symptoms and dependence of subjective assessments of the level of cognitive functioning.

  1. The political and scientific challenges in evaluating compulsory drug treatment centers in Southeast Asia

    OpenAIRE

    Vuong, Thu; Nguyen, Nhu; Le, Giang; Shanahan, Marian; Ali, Robert; Ritter, Alison

    2017-01-01

    Background In Vietnam, like many countries in Southeast Asia, the commonly used approach of center-based compulsory drug treatment (CCT) has been criticized on human rights ground. Meanwhile, community-based voluntary methadone maintenance treatment (MMT) has been implemented for nearly a decade with promising results. Reform-minded leaders have been seeking empirical evidence of the costs and effectiveness associated with these two main treatment modalities. Conducting evaluations of these t...

  2. Tracers confirm downward mixing of Tyrrhenian Sea upper waters associated with the Eastern Mediterranean Transient

    Directory of Open Access Journals (Sweden)

    W. Roether

    2011-01-01

    Full Text Available Observations of tritium and 3He in the Tyrrhenian Sea, 1987–2009, confirm the enhanced vertical mixing of intermediate waters into the deep waters that has been noted and associated with the Eastern Mediterranean Transient in previous studies. Our evidence for the mixing rests on increasing tracer concentrations in the Tyrrhenian deep waters, accompanied by decreases in the upper waters, which are supplied from the Eastern Mediterranean. The downward transfer is particularly evident between 1987 and 1997. Later on, information partly rests on increasing tritium-3He ages; here we correct the observed 3He for contributions released from the ocean floor. The Tyrrhenian tracer distributions are fully compatible with data upstream of the Sicily Strait and in the Western Mediterranean. The tracer data show that mixing reached to the bottom and confirm a cyclonic nature of the deep water circulation in the Tyrrhenian. They furthermore indicate that horizontal homogenization of the deep waters occurs on a time scale of roughly 5 years. Various features point to a reduced impact of Western Mediterranean Deep Water (WMDW in the Tyrrhenian during the enhanced-mixing period. This is an important finding because it implies less upward mixing of WMDW, which has been named a major process to enable the WMDW to leave the Mediterranean via the Gibraltar Strait. On the other hand, the TDW outflow for several years represented a major influx of enhanced salinity and density waters into the deep-water range of the Western Mediterranean.

  3. Hidden Gains: Effects of Early U.S. Compulsory Schooling Laws on Attendance and Attainment by Social Background

    Science.gov (United States)

    Rauscher, Emily

    2014-01-01

    Research on early compulsory schooling laws finds minimal effects on attendance but fails to investigate heterogeneous effects. Similarly, research proposes limited contexts in which expansion policies can increase equality but has difficulty separating policy and cohort effects. Capitalizing on within-country variation in timing of early…

  4. Groundwater mixing at fracture intersections triggers massive iron-rich microbial mats

    Science.gov (United States)

    Bochet, O.; Le Borgne, T.; Bethencourt, L.; Aquilina, L.; Dufresne, A.; Pédrot, M.; Farasin, J.; Abbott, B. W.; Labasque, T.; Chatton, E.; Lavenant, N.; Petton, C.

    2017-12-01

    While most freshwater on Earth resides and flows in groundwater systems, these deep subsurface environments are often assumed to have little biogeochemical activity compared to surface environments. Here we report a massive microbial mat of iron-oxidizing bacteria, flourishing 60 meters below the surface, far below the mixing zone where most microbial activity is believed to occur. The abundance of microtubular structures in the mat hinted at the prevalence of of Leptothrix ochracea, but metagenomic analysis revealed a diverse consortium of iron-oxidizing bacteria dominated by unknown members of the Gallionellaceae family. This deep biogeochemical hot spot formed at the intersection of bedrock fractures, which maintain redox gradients by mixing water with different residence times and chemical compositions. Using measured fracture properties and hydrological conditions we developed a quantitative model to simulate the reactive zone where such deep hot spots could occur. While seasonal fluctuations are generally thought to decrease with depth, we found that meter-scale changes in water table level moved the depth of the reactive zone hundreds of meters because the microaerophilic threshold for ironoxidizers is highly sensitive to changes in mixing rates at fracture intersections. These results demonstrate that dynamic microbial communities can be sustained deep below the surface in bedrock fractures. Given the ubiquity of fractures at multiple scales in Earth's subsurface, such deep hot spots may strongly influence global biogeochemical cycles.

  5. Shifts in the bacterial community composition along deep soil profiles in monospecific and mixed stands of Eucalyptus grandis and Acacia mangium

    Science.gov (United States)

    de Andrade, Pedro Avelino Maia; Bini, Daniel; Durrer, Ademir; Robin, Agnès; Bouillet, Jean Pierre; Andreote, Fernando Dini; Cardoso, Elke Jurandy Bran Nogueira

    2017-01-01

    Our knowledge of the rhizosphere bacterial communities in deep soils and the role of Eucalyptus and Acacia on the structure of these communities remains very limited. In this study, we targeted the bacterial community along a depth profile (0 to 800 cm) and compared community structure in monospecific or mixed plantations of Acacia mangium and Eucalyptus grandis. We applied quantitative PCR (qPCR) and sequence the V6 region of the 16S rRNA gene to characterize composition of bacterial communities. We identified a decrease in bacterial abundance with soil depth, and differences in community patterns between monospecific and mixed cultivations. Sequence analysis indicated a prevalent effect of soil depth on bacterial communities in the mixed plant cultivation system, and a remarkable differentiation of bacterial communities in areas solely cultivated with Eucalyptus. The groups most influenced by soil depth were Proteobacteria and Acidobacteria (more frequent in samples between 0 and 300 cm). The predominant bacterial groups differentially displayed in the monospecific stands of Eucalyptus were Firmicutes and Proteobacteria. Our results suggest that the addition of an N2-fixing tree in a monospecific cultivation system modulates bacterial community composition even at a great depth. We conclude that co-cultivation systems may represent a key strategy to improve soil resources and to establish more sustainable cultivation of Eucalyptus in Brazil. PMID:28686690

  6. INNOVATIVE APPROACH IN THE COMPULSORY HEALTH INSURANCE TARIFF SETTING

    Directory of Open Access Journals (Sweden)

    M. Yu. Zasypkin

    2015-02-01

    Full Text Available Development of a single channel financing in the health system of the Russian Federation based on the standards of the compulsory health insurance (CHI requires a single channel financing of the health system through the CHI as one of the main direction using payment of the medical services in the form of so-called «full» tariff [1-12].It is not a secret that for many years the medical services tariff in the CHI system contained from only five items of expenditures (salary, charges on payroll, soft goods and clothing, medicines, bandages, other medical expenses, and food. On one hand, such defective tariff was based on the parallel government financing of the medical institutions (MIs, on the other hand, because of this tariff, the manager was hoppled in the control of the financial flows.

  7. The role of Southern Ocean mixing and upwelling in glacial-interglacial atmospheric CO2 change

    International Nuclear Information System (INIS)

    Watson, Andrew J.; Naveira Garabato, Alberto C.

    2006-01-01

    Decreased ventilation of the Southern Ocean in glacial time is implicated in most explanations of lower glacial atmospheric CO 2 . Today, the deep (>2000 m) ocean south of the Polar Front is rapidly ventilated from below, with the interaction of deep currents with topography driving high mixing rates well up into the water column. We show from a buoyancy budget that mixing rates are high in all the deep waters of the Southern Ocean. Between the surface and 2000 m depth, water is upwelled by a residual meridional overturning that is directly linked to buoyancy fluxes through the ocean surface. Combined with the rapid deep mixing, this upwelling serves to return deep water to the surface on a short time scale. We propose two new mechanisms by which, in glacial time, the deep Southern Ocean may have been more isolated from the surface. Firstly, the deep ocean appears to have been more stratified because of denser bottom water resulting from intense sea ice formation near Antarctica. The greater stratification would have slowed the deep mixing. Secondly, subzero atmospheric temperatures may have meant that the present-day buoyancy flux from the atmosphere to the ocean surface was reduced or reversed. This in turn would have reduced or eliminated the upwelling (contrary to a common assumption, upwelling is not solely a function of the wind stress but is coupled to the air/sea buoyancy flux too). The observed very close link between Antarctic temperatures and atmospheric CO 2 could then be explained as a natural consequence of the connection between the air/sea buoyancy flux and upwelling in the Southern Ocean, if slower ventilation of the Southern Ocean led to lower atmospheric CO 2 . Here we use a box model, similar to those of previous authors, to show that weaker mixing and reduced upwelling in the Southern Ocean can explain the low glacial atmospheric CO 2 in such a formulation

  8. Licença compulsória do efavirenz no Brasil em 2007: contextualização Compulsory licensing of efavirenz in Brazil in 2007: contextualization

    Directory of Open Access Journals (Sweden)

    William C. V. Rodrigues

    2009-12-01

    Full Text Available The present article aims at contextualizing the first Brazilian experience with compulsory licensing, which functions as a defense mechanism to prevent excessive pricing by holders of patents. According to this mechanism, a government can authorize a third party to explore the patented object (in this case a drug without previous consent from the patent holder. On May 4, 2007, Brazil officially issued compulsory licensing of the antiretroviral drug efavirenz for public, non-commercial use. Initially, generic versions of the drug were purchased from laboratories in India. The next step was the manufacture of efavirenz by Farmanguinhos, official pharmaceutical laboratory (Fundação Osvaldo Cruz. It is concluded that the decision made by the Brazilian government to issue compulsory licensing of efavirenz nwas correct, taking into account the projected savings of US$ 236.8 until 2012 and the guarantee of availability of efavirenz, the most usual free antiretroviral treatment provided in Brazil.

  9. Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Industry

    Science.gov (United States)

    Wheelahan, Leesa; Buchanan, John; Yu, Serena

    2015-01-01

    This summary brings together the relevant key findings for industry from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between vocational education and training (VET) and…

  10. INTRODUCTION OF VAT SPLIT PAYMENT MECHANISM IN ROMANIA – COMPULSORY VERSUS OPTIONALLY

    Directory of Open Access Journals (Sweden)

    ECOBICI NICOLAE

    2017-11-01

    Full Text Available The objective of this article is to analyze the implications of introducing the VAT split payment mechanism in Romania, as it is regulated, as a compulsory system, through GO 23/2017 respectively, as well as in the case of the modification of the regulation in the sense of replacing the compulsory by optionality. We will analyze the effects of Ordinance 23/2017 of the Romanian Government regarding the mandatory distinctly payment of VAT for Romanian legal persons, registered or not for VAT purposes, as well as the result which the Government hopes to obtain as a result of the application of this provision, on the one hand. On the other hand, we will discuss the effects of a change in regulation for the optionally application of the VAT split payment mechanism, as of January 1, 2018, as compared with the amendments already approved by the Romanian Senate on October 31st, 2017. The structure of the article includes the following main sections: a briefly presents of the VAT split payment mechanism, as it was originally regulated by GO 23/2017; the second part includes the analysis of the implications of introducing the VAT split payment mechanism on legal entities and the state, in the initial phase of the Ordinance; the third part is devoted to the presentation of the amendments approved at the end of October 2017, respectively to the recommendations on amendments needed to be taken into account by the Chamber of Deputies, and the last part will include the conclusions and recommendations.

  11. Highly efficient deep ultraviolet generation by sum-frequency mixing ...

    Indian Academy of Sciences (India)

    Generation of deep ultraviolet radiation at 210 nm by Type-I third harmonic generation is achieved in a pair of BBO crystals with conversion efficiency as high as 36%. The fundamental source is the dye laser radiation pumped by the second harmonic of a Q-switched Nd : YAG laser. A walk-off compensated configuration ...

  12. Negative moods correlate with craving in female methamphetamine users enrolled in compulsory detoxification

    Directory of Open Access Journals (Sweden)

    Shen Wenwen

    2012-10-01

    Full Text Available Abstract Background Methamphetamine (METH use, especially in females, has become a growing public health concern in China. In this study, we aimed to characterize the factors that contributed to drug craving in female METH users under isolated compulsory detoxification. We characterized factors contributing to craving such as duration of detoxification, history of drug use and self-reported mood state. Methods Subjects (N=113 undergoing a 1- to 3-year METH detoxification program were recruited from the Zhejiang Compulsory Detoxification Center for Women. The Questionnaire of METH-use Urge (QMU was used to evaluate the level of craving for METH. The Abbreviate Profile of Mood States (A-POMS was applied as an assessment for the negative mood disturbances. Results The participants were at a mean age of 25.2, primarily lowly educated and unemployed, and single. Smoking was the only route of METH administration at an average dose of 0.5 g/day, and 4 times/week. The reported craving level was positively correlated with the negative mood disturbances and the weekly dose of METH, but independent of the duration of detoxification. Furthermore, all five aspects of negative mood disturbances, including fatigue, bewilderment, anxiety, depression and hostility, were shown to positively correlate to the self-reported craving level after controlling for weekly dose of METH. Conclusions The data demonstrate a robust correlation between mood distress and craving for METH. Our results call for close evaluation of mood distress in treatment of METH users in China.

  13. Deep shaft high rate aerobic digestion: laboratory and pilot plant performance

    Energy Technology Data Exchange (ETDEWEB)

    Tran, F; Gannon, D

    1981-01-01

    The Deep Shaft is essentially an air-lift reactor, sunk deep in the ground (100-160 m); the resulting high hydrostatic pressure together with very efficient mixing in the shaft provide extremely high O transfer efficiencies (O.T.E.) of less than or equal to 90% vs. 4-20% in other aerators. This high O.T.E. suggests real potential for Deep-Shaft technology in the aerobic digestion of sludges and animal wastes: with conventional aerobic digesters an O.T.E. over 8% is extremely difficult to achieve. Laboratory and pilot plant Deep-Shaft aerobic digester studies carried out at Eco-Research's Pointe Claire, Quebec laboratories, and at the Paris, Ontario pilot Deep-Shaft digester are described.

  14. North Jamaican Deep Fore-Reef Sponges

    NARCIS (Netherlands)

    Lehnert, Helmut; Soest, van R.W.M.

    1996-01-01

    An unexpectedly high amount of new species, revealed within only one hour of summarized bottom time, leads to the conclusion that the sponge fauna of the steep slopes of the deep fore-reef is still largely unknown. Four mixed gas dives at depths between 70 and 90 m, performed in May and June, 1993,

  15. Self-Stigma and Quality of Life among People with Mental Illness Who Receive Compulsory Community Treatment Services

    Science.gov (United States)

    Livingston, James

    2012-01-01

    The present study was designed to examine the relationship between self-stigma and quality of life over a one year time period for 71 people with mental illness who were receiving compulsory community mental health treatment. It was hypothesized that, over time, self-stigma would have the direct effect of eroding quality of life among people with…

  16. Two case studies on the origin of aqueous sulphate in deep crystalline rocks

    International Nuclear Information System (INIS)

    Michelot, J.L.; Fontes, J.C.

    1987-01-01

    The paper reports preliminary results obtained from studies in Central Sweden (Stripa) and in Northern Switzerland (Boettstein). The isotopic compositions ( 34 S, 18 O) of dissolved sulphates in shallow and deep groundwaters from the Stripa test site show that (1) the origins of the salinity in the shallow and in the deep groundwaters are probably different, (2) the low sulphate content of the waters collected from the upper part of the deep aquifer system could be derived from the shallow aqueous sulphate through bacterial reduction, (3) a deeper bulk of sulphate can be identified. After examining several hypotheses, a Permian or Triassic origin is attributed to this deep sulphate. Boettstein is the first drilled borehole of the NAGRA (Swiss National Co-operative for the Storage of Radioactive Wastes programme). In the 34 S versus 18 O diagram, most of the representative points of samples collected at different depths (from apparently different water bodies), lie along a straight line. It seems that this line cannot be a reduction line, nor a precipitation line (gypsum or anhydrite). It is thus interpreted as a mixing line. The end members of this mixing line are still unknown. However, a deep brine is present at the bottom of the system, probably related to brines circulating in the Permian channel found at the same depth, a few kilometres away. A working hypothesis involving this deep brine as a source for both end members of the mixing, through two different processes, is presented, with the problem of possible connections between the different water bodies. (author). 16 refs, 5 figs, 2 tabs

  17. THE WAY TO THE COMPULSORY EDUCATION (VSEOBUCH: ACHIEVEMENTS AND CHALLENGES IN THE DEVELOPMENT OF PUBLIC EDUCATION IN RURAL AREAS OF PERM PROVINCE IN THE SECOND HALF OF THE XIX – EARLY XX CENTURY

    Directory of Open Access Journals (Sweden)

    Svetlana V. Golikova

    2016-01-01

    Full Text Available The aim of the publication is the analysis of formation and development of the primary school in the post-reform period in rural areas of the Perm province in terms of its strategic perspective which suggests transition to compulsory primary education as an integral part of the process of creating social and cultural environment of modern times.Methods. Education is observed in terms of institutional and systemic approaches, and the post-reform stage of its development is analyzed in the context of the modernization theory. Historical-dynamic analysis and comparative-historical method are mostly used when systemizing factual data.Results. The article reveals basic stages and characteristics of elementary public schools in the Perm province countryside during pre-vseobuch (compulsory education period. The dynamics of the educational process in reference to the number of schools and enrollments is shown; the scale of the process and the participation of the «zemstvo system» (i.e. district council and the Orthodox Church in it are estimated. The clergy’s view on parochial schools as a special type of educational institutions is also described. Difficulties faced by public school policy during the implementation of rural compulsory education in the province are marked. It is shown that to achieve total literacy in the rural areas in the pre-revolutionary period was impossible in spite of the accelerated speed of the school education and substantial progress in the organization of the compulsory primary education.Scientific novelty. Turning to the history of compulsory elementary schools in terms of the «compulsory education paradigm» offers the possibility to set clear criteria for assessing the level of development of the education system and show how the compulsory education environment was formed.Practical significance. The results of the study and the facts introduced into scientific use can be adopted as a part of

  18. Mixing of solids

    CERN Document Server

    Weinekötter, Ralf

    2000-01-01

    This book is a welcome edition to the Particle Technology Series, formerly Powder Technology Series. It is the second book in the series which describes powder mixing and we make no excuses for that. The topic of powder mixing is fundamental to powder technology and is one which always aroses interest. That will not change. As powder products become more complex they will pose new mixing problems. The solutions lie in the intelligent use of equipment, an understanding of powder properties and a good knowledge of basic statistics. The authors of this book have presented those three ingredients with great clarity. The book is based on long experience and deep thought, I have enjoyed reading it and am pleased to recommend it. Delft University of Technology, NL-Delft, July 1999 Brian Scarlett, Series Editor IX VII Foreword to the English Edition In response to many enquiries from industrial organisations and institutes involved with the technology of processing bulk materials, we are pleased to present the Englis...

  19. Stability of embankments over cement deep soil mixing columns; Estabilidad de terraplenes sobre columnas de suelo-cemento

    Energy Technology Data Exchange (ETDEWEB)

    Morilla Moar, P.; Melentijevic, S.

    2014-07-01

    The deep soil mixing (DSM) is one of the ground improvement methods used for the construction of embankments over soft soils. DSM column-supported embankments are constructed over soft soils to accelerate its construction, improve embankment stability, increase bearing capacity and control of total and differential settlements. There are two traditional design methods, the Japanese (rigid columns) and the scandinavian (soft and semi-rigid columns). Based on Laboratory analysis and numerical analysis these traditional approaches have been questioned by several authors due to its overestimation of the embankment stability considering that the most common failures types are not assumed. This paper presents a brief review of traditional design methods for embankments on DSM columns constructed in soft soils, studies carried out determine the most likely failure types of DSM columns, methods to decrease the overestimation when using limit equilibrium methods and numerical analysis methods that permit detect appropriate failure modes in DSM columns. Finally a case study was assessed using both limited equilibrium and finite element methods which confirmed the overestimation in the factors of safety on embankment stability over DSM columns. (Author)

  20. Should I take Further Mathematics? Physics undergraduates’ experiences of post-compulsory Mathematics

    Science.gov (United States)

    Bowyer, Jessica; Darlington, Ellie

    2017-01-01

    It is essential that physics undergraduates are appropriately prepared for the mathematical demands of their course. This study investigated physics students’ perceptions of post-compulsory mathematics as preparation for their degree course. 494 physics undergraduates responded to an online questionnaire about their experiences of A-level Mathematics and Further Mathematics. The findings suggest that physics undergraduates would benefit from studying Further Mathematics and specialising in mechanics during their A-level studies. As both A-level Mathematics and Further Mathematics are being reformed, universities should look closely at the benefits of Further Mathematics as preparation for their physics courses and either increase their admissions requirements, or recommend that students take Further Mathematics.

  1. Deep amplicon sequencing reveals mixed phytoplasma infection within single grapevine plants

    DEFF Research Database (Denmark)

    Nicolaisen, Mogens; Contaldo, Nicoletta; Makarova, Olga

    2011-01-01

    The diversity of phytoplasmas within single plants has not yet been fully investigated. In this project, deep amplicon sequencing was used to generate 50,926 phytoplasma sequences from 11 phytoplasma-infected grapevine samples from a PCR amplicon in the 5' end of the 16S region. After clustering ...

  2. Importance of deep mixing for initiating the North Atlantic spring bloom

    DEFF Research Database (Denmark)

    Riisgaard, Karen; Paulsen, Maria Lund; Thingstad, T. Frede

    The phytoplankton spring bloom is one of the most important recurrent events in the sup-polar part of the Atlantic Ocean. The classical idea is that the bloom is controlled by nutrients and light, but recent observations challenge this hypothesis. During repeated visits to stations in the deep...

  3. Applied model for the growth of the daytime mixed layer

    DEFF Research Database (Denmark)

    Batchvarova, E.; Gryning, Sven-Erik

    1991-01-01

    numerically. When the mixed layer is shallow or the atmosphere nearly neutrally stratified, the growth is controlled mainly by mechanical turbulence. When the layer is deep, its growth is controlled mainly by convective turbulence. The model is applied on a data set of the evolution of the height of the mixed...... layer in the morning hours, when both mechanical and convective turbulence contribute to the growth process. Realistic mixed-layer developments are obtained....

  4. Resister's logic: the anti-vaccination arguments of Alfred Russel Wallace and their role in the debates over compulsory vaccination in England, 1870-1907.

    Science.gov (United States)

    Fichman, Martin; Keelan, Jennifer E

    2007-09-01

    In the 1880s, Alfred Russel Wallace, the celebrated co-discoverer of natural selection, launched himself into the centre of a politicised and polarised debate over the unpopular compulsory vaccination laws in England. Wallace never wavered in his belief that smallpox vaccination was useless and likely dangerous. Six years before his death, the anti-vaccinationists successfully secured a conscience clause that effectively dismantled the compulsory vaccination laws. Several other important Victorian scientists joined Wallace in the fight to repeal compulsory vaccination arguing that widely held views on the effectiveness of vaccination and evidence for immunity were inconclusive in the light of (then) contemporary standards of evidence. This article situates Wallace's anti-vaccination logic within the broader matrix of sociopolitical and cultural reform movements of the late Victorian era. Additionally it provides the first detailed analysis of his critique of vaccination science, in particular the role statistics played in his arguments. In this period, both pro-vaccinationists and anti-vaccinationists invested great efforts in collating and analysing statistical data sets that either supported or refuted the claims of vaccination's effectiveness. While each side presented 'controlled' case studies to support their assertions, without an unambiguous test to measure or demonstrate vaccination's effectiveness, the anti-vaccinationists continued to mount credible statistical critiques of vaccination science.

  5. Developing a Model of Compulsory Basic Education Completion Acceleration in Support of Millennium Development Goals in Magelang, Indonesia

    Science.gov (United States)

    Sukarno; Haryati, Sri

    2015-01-01

    This article reports Year One of a two-year study to develop a model to accelerate compulsory basic education completion toward Millennium Development Goals (MDGs) in Magelang, Indonesia. The study focuses on five issues: (1) profile of MDGs in Magelang, (2) achievement of MDGs, (3) problems in MDGs implementation, (4) model of compulsary basic…

  6. The Returns to Education in China: Evidence from the 1986 Compulsory Education Law. NBER Working Paper No. 18189

    Science.gov (United States)

    Fang, Hai; Eggleston, Karen N.; Rizzo, John A.; Rozelle, Scott; Zeckhauser, Richard J.

    2012-01-01

    As China transforms from a socialist planned economy to a market-oriented economy, its returns to education are expected to rise to meet those found in middle-income established market economies. This study employs a plausible instrument for education: the China Compulsory Education Law of 1986. We use differences among provinces in the dates of…

  7. Optional Protocol concerning the compulsory settlement of disputes to the Vienna Convention on civil liability for nuclear damage

    International Nuclear Information System (INIS)

    1999-01-01

    The document reproduces the text of the Optional Protocol Concerning the Compulsory Settlement of Disputes to the Vienna Convention on Civil Liability for Nuclear Damage which was adopted on 21 May 1963 by the International Conference held in Vienna from 29 April to 19 May 1963. It came into force on 13 May 1999

  8. Robust and Specific Personality Traits as Predictors of Adolescents' Final Grades and GPA at the End of Compulsory Schooling

    Science.gov (United States)

    Smrtnik Vitulic, Helena; Zupancic, Maja

    2013-01-01

    The study investigated the predictive value of robust and specific personality traits in adolescents (M[subscript age]?=?14.7 years), in explaining their academic achievement at the end of basic compulsory schooling. Personality data were obtained through self, maternal, and peer reports using the Inventory of Child/Adolescent Individual…

  9. Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Qualification & Approval Bodies

    Science.gov (United States)

    Wheelahan, Leesa; Buchanan, John; Yu, Serena

    2015-01-01

    This summary pulls together the relevant key findings for qualification and approval bodies from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between vocational education…

  10. Deep Mixing of 3He: Reconciling Big Bang and Stellar Nucleosynthesis

    International Nuclear Information System (INIS)

    Eggleton, P P; Dearborn, D P; Lattanzio, J

    2006-01-01

    Low-mass stars, ∼ 1-2 solar masses, near the Main Sequence are efficient at producing 3 He, which they mix into the convective envelope on the giant branch and should distribute into the Galaxy by way of envelope loss. This process is so efficient that it is difficult to reconcile the low observed cosmic abundance of 3 He with the predictions of both stellar and Big Bang nucleosynthesis. In this paper we find, by modeling a red giant with a fully three-dimensional hydrodynamic code and a full nucleosynthetic network, that mixing arises in the supposedly stable and radiative zone between the hydrogen-burning shell and the base of the convective envelope. This mixing is due to Rayleigh-Taylor instability within a zone just above the hydrogen-burning shell, where a nuclear reaction lowers the mean molecular weight slightly. Thus we are able to remove the threat that 3 He production in low-mass stars poses to the Big Bang nucleosynthesis of 3 He

  11. Deep mixing of 3He: reconciling Big Bang and stellar nucleosynthesis.

    Science.gov (United States)

    Eggleton, Peter P; Dearborn, David S P; Lattanzio, John C

    2006-12-08

    Low-mass stars, approximately 1 to 2 solar masses, near the Main Sequence are efficient at producing the helium isotope 3He, which they mix into the convective envelope on the giant branch and should distribute into the Galaxy by way of envelope loss. This process is so efficient that it is difficult to reconcile the low observed cosmic abundance of 3He with the predictions of both stellar and Big Bang nucleosynthesis. Here we find, by modeling a red giant with a fully three-dimensional hydrodynamic code and a full nucleosynthetic network, that mixing arises in the supposedly stable and radiative zone between the hydrogen-burning shell and the base of the convective envelope. This mixing is due to Rayleigh-Taylor instability within a zone just above the hydrogen-burning shell, where a nuclear reaction lowers the mean molecular weight slightly. Thus, we are able to remove the threat that 3He production in low-mass stars poses to the Big Bang nucleosynthesis of 3He.

  12. Energy-efficiency instruments in the electricity area; Instrumente fuer Energieeffizienz im Elektrizitaetsbereich. Auslaendische Erfahrungen und Instrumenten-Mix fuer die Schweiz

    Energy Technology Data Exchange (ETDEWEB)

    Hammer, S; Oettli, B; Schneider, Ch; Iten, R [Infras, Zuerich (Switzerland); Peherstorfer, N [Oesterreichische Energieagentur, Wien (Austria)

    2007-06-15

    This comprehensive report for the Swiss Federal Office of Energy (SFOE) describes a mix of instruments that could increase the efficiency of electricity usage in Switzerland. The basis for the development of these instruments - the experience gained in Europe in this area - is discussed. Explicitly not discussed are energy and electricity steering taxes, which could also be part of a future instrument-mix. The measures suggested include the setting of compulsory long-term reduction targets that are to form the basis for strategies and measures to be taken in particular areas and the development of an appropriate instrument-mix for this purpose. These could include regulations and labels, a national fund and certificate trading. Suppliers of electricity could be committed to increasing the efficiency of electricity use and national programmes could also attempt to influence consumer habits. The instruments should, according to the authors, be based on the existing legal framework and use know-how and structures that are already available.

  13. Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Government & Policy-Makers

    Science.gov (United States)

    Wheelahan, Leesa; Buchanan, John; Yu, Serena

    2015-01-01

    This summary brings together the relevant key findings for government and policy-makers from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between vocational education and…

  14. Rating the Efficiency of Regional Health Systems and Compulsory Health Insurance

    Directory of Open Access Journals (Sweden)

    Tatyana Nikolayevna Russkikh

    2015-12-01

    Full Text Available In the face of increasing of the regional differentiation of the health systems and compulsory health insurance, the comparative analysis and efficiency assessment of their performance in the context of the subjects of the Russian Federation becomes particularly relevant. Therefore, the research is focused on the regional health systems and compulsory health insurance (CHI, and the subject matter of the study is the analysis of the system performance. In the article, the comparative analysis of the authors’ approaches to the formation of efficiency criteria of the performance of regional health systems and CHI, as well as to the development of a typology of the constituent entities of the Russian Federation based on these criteria is conducted. The authors propose a system of indicators to measure the economic, medical and social efficiency of the systems under consideration. Moreover, a set of indicators of economic efficiency forms two groups of indicators. The first group of indicators reflects the financial performance, and the second — the structural efficiency. A methodological approach to the formation of the rating for subjects of the Russian Federation according to the levels of efficiency, based on the procedures of cluster analysis and fuzzy mathematics are developed. A feature of the proposed approach to the construction of a typology of the subjects in terms of efficiency is the introduction of a reference subject with the national average performance indicators system that allows to qualitatively assess the effectiveness of regional health systems and CHI by comparing them with the «reference subject». The results of the empirical research have indicated a high differentiation of the subjects of the Russian Federation in terms of economic efficiency, have allowed to identify the subjects-outsiders. The theoretical and practical results can be used for the rational choice of priorities of the state policy in the field of the

  15. Interannual control of plankton communities by deep winter mixing and prey/predator interactions in the NW Mediterranean: Results from a 30-year 3D modeling study

    Science.gov (United States)

    Auger, P. A.; Ulses, C.; Estournel, C.; Stemmann, L.; Somot, S.; Diaz, F.

    2014-05-01

    A realistic modeling approach is designed to address the role of winter mixing on the interannual variability of plankton dynamics in the north-western (NW) Mediterranean basin. For the first time, a high-resolution coupled hydrodynamic-biogeochemical model (Eco3m-S) covering a 30-year period (1976-2005) is validated on available in situ and satellite data for the NW Mediterranean. In this region, cold, dry winds in winter often lead to deep convection and strong upwelling of nutrients into the euphotic layer. High nutrient contents at the end of winter then support the development of a strong spring bloom of phytoplankton. Model results indicate that annual primary production is not affected by winter mixing due to seasonal balance (minimum in winter and maximum in spring). However, the total annual water column-integrated phytoplankton biomass appears to be favored by winter mixing because zooplankton grazing activity is low in winter and early spring. This reduced grazing is explained here by the rarefaction of prey due to both light limitation and the effect of mixing-induced dilution on prey/predator interactions. A negative impact of winter mixing on winter zooplankton biomass is generally simulated except for mesozooplankton. This difference is assumed to stem from the lower parameterized mortality, top trophic position and detritivorous diet of mesozooplankton in the model. Moreover, model suggests that the variability of annual mesozooplankton biomass is principally modulated by the effects of winter mixing on winter biomass. Thus, interannual variability of winter nutrient contents in the euphotic layer, resulting from winter mixing, would control spring primary production and thus annual mesozooplankton biomass. Our results show a bottom-up control of mesozooplankton communities, as observed at a coastal location of the Ligurian Sea.

  16. Mixing processes at the subsurface layer in the Amundsen Sea shelf region

    Science.gov (United States)

    Mojica, J.; Djoumna, G.; Francis, D. K.; Holland, D.

    2017-12-01

    In the Amundsen Sea shelf region, mixing processes promote an upward transport of diapycnal fluxes of heat and salt from the subsurface to the surface mixing layer. Here we estimate the diapycnal mixing rates on the Amundsen shelf from a multi-year mooring cluster and five research cruises. By applying fine-scale parameterizations, the mixing rates obtained were higher near the southern end of Pine Island glacier front and exceeded 10-2 m2s-1. The eddy diffusivity increased near the critical latitude (74o 28' S) for semi-diurnal M2 tides, which coincided with near-critical topography on the shelf. This condition favored the generation of internal waves of M2 frequency. The semi-diurnal dynamic enhanced the mixing that potentially affected the heat budget and the circulation of the modified Circumpolar Deep Water. This can be observed in the characteristics of water exchange both below the ice shelves and between the continental shelf and the ice shelf cavities. The location of the critical latitude and critical topography provided favorable conditions for the generation of internal waves. KEYWORDS: Mixing processes, diapycnal fluxes, critical latitude, Circumpolar Deep Water.

  17. Social Marketing Analysis of Attitude Toward Compulsory Earthquake Insurance in Turkey(Türkiye’de Zorunlu Deprem Sigortasına Yönelik Tutumun Sosyal Pazarlama Kapsamında Analizi

    Directory of Open Access Journals (Sweden)

    Gülnil AYDIN

    2016-08-01

    Full Text Available This study aims to explore the reasons behind the low-level purchases of compulsory earthquake insurance policies in Turkey. Based on online surveys with 667 people the findings of the study point out that there is a major communications gap to be filled in by the authorities and the insurance companies. The findings of the study also show that in addition to the demographic variables the personality characteristics of people also influence the attitude towards and the purchasing of compulsory earthquake insurance policies

  18. Analysis of Measures for Attention to Diversity in Compulsory Secondary Education: The Case of the Region of Murcia, Spain

    Science.gov (United States)

    Arnaiz, Pilar; Martinez, Rogelio; de Haro, Remedios; Escarbajal, Andres

    2013-01-01

    In this paper, we present an analysis of the implementation of measures of attention to diversity for students with special educational support needs studying Compulsory Secondary Education (12-16 years) in the Region of Murcia, Spain. Our aim is to learn about the organisational and curricular structures implemented in five secondary education…

  19. Simulation of deep ventilation in Crater Lake, Oregon, 1951–2099

    Science.gov (United States)

    Wood, Tamara M.; Wherry, Susan A.; Piccolroaz, Sebastiano; Girdner, Scott F

    2016-05-04

    The frequency of deep ventilation events in Crater Lake, a caldera lake in the Oregon Cascade Mountains, was simulated in six future climate scenarios, using a 1-dimensional deep ventilation model (1DDV) that was developed to simulate the ventilation of deep water initiated by reverse stratification and subsequent thermobaric instability. The model was calibrated and validated with lake temperature data collected from 1994 to 2011. Wind and air temperature data from three general circulation models and two representative concentration pathways were used to simulate the change in lake temperature and the frequency of deep ventilation events in possible future climates. The lumped model air2water was used to project lake surface temperature, a required boundary condition for the lake model, based on air temperature in the future climates.The 1DDV model was used to simulate daily water temperature profiles through 2099. All future climate scenarios projected increased water temperature throughout the water column and a substantive reduction in the frequency of deep ventilation events. The least extreme scenario projected the frequency of deep ventilation events to decrease from about 1 in 2 years in current conditions to about 1 in 3 years by 2100. The most extreme scenario considered projected the frequency of deep ventilation events to be about 1 in 7.7 years by 2100. All scenarios predicted that the temperature of the entire water column will be greater than 4 °C for increasing lengths of time in the future and that the conditions required for thermobaric instability induced mixing will become rare or non-existent.The disruption of deep ventilation by itself does not provide a complete picture of the potential ecological and water quality consequences of warming climate to Crater Lake. Estimating the effect of warming climate on deep water oxygen depletion and water clarity will require careful modeling studies to combine the physical mixing processes affected by

  20. The Care Manager's Dilemma: Balancing Human Rights with Risk Management under the Intellectual Disability (Compulsory Care and Rehabilitation) Act 2003

    Science.gov (United States)

    Prebble, Kate; Diesfeld, Kate; Frey, Rosemary; Sutton, Daniel; Honey, Michelle; Vickery, Russell; McKenna, Brian

    2013-01-01

    In New Zealand, the Intellectual Disability (Compulsory Care and Rehabilitation) Act 2003 provides diversion for persons with an intellectual disability who have been charged with, or convicted of, a criminal offence. This unique Act moves the responsibility for such "care recipients" from the criminal justice system to a disability…

  1. Seismic tomography and mixing in the deep earth

    Directory of Open Access Journals (Sweden)

    W. R. Peltier

    1995-01-01

    Full Text Available Recently constructed tomographic models of the lateral heterogeneity of elastic properties in the Earth's mantle are contrasted in terms of their implications concerning the extent to which the endothermic phase transformation at 660 km depth is influencing the radial style of mixing. Previously published whole mantle and split mantle tomographic reconstructions, SH8/WMI3 and SH8/U4L8 respectively, fit the seismic observations equally well but disagree on the extent to which radial mixing may be impeded across this depth horizon. We show that inferences from seismic tomographic images based on the application of diagnostic functions (global and regional variance spectra and the radial correlation function lead to the conclusion that the mantle circulation is whole mantle in style if model SH8/WM13 is employed. The split mantle tomographic inversion SHS/U4L8 leads to the contradictory conclusion that the mantle circulation is significantly impeded across the 660 km depth horizon. This latter interpretation is reinforced when we employ the new higher resolution split mantle model SH12/U7L5 in our calculations. We demonstrate that the depth-dependent radial heat flow delivered by both of the split models implies the existence of a thermal boundary layer at 660 km depth, and therefore significant layering, whereas that delivered by the whole mantle model does not. By insisting that the depth-dependent viscosity profile of the mantle be compatible with the thermal structure if the flow were layered, we argue that the split mantle tomographic inversions lead to a self-consistent description of geodynamic constraints (geoid and postglacial rebound data.

  2. Surface wind mixing in the Regional Ocean Modeling System (ROMS)

    Science.gov (United States)

    Robertson, Robin; Hartlipp, Paul

    2017-12-01

    Mixing at the ocean surface is key for atmosphere-ocean interactions and the distribution of heat, energy, and gases in the upper ocean. Winds are the primary force for surface mixing. To properly simulate upper ocean dynamics and the flux of these quantities within the upper ocean, models must reproduce mixing in the upper ocean. To evaluate the performance of the Regional Ocean Modeling System (ROMS) in replicating the surface mixing, the results of four different vertical mixing parameterizations were compared against observations, using the surface mixed layer depth, the temperature fields, and observed diffusivities for comparisons. The vertical mixing parameterizations investigated were Mellor- Yamada 2.5 level turbulent closure (MY), Large- McWilliams- Doney Kpp (LMD), Nakanishi- Niino (NN), and the generic length scale (GLS) schemes. This was done for one temperate site in deep water in the Eastern Pacific and three shallow water sites in the Baltic Sea. The model reproduced the surface mixed layer depth reasonably well for all sites; however, the temperature fields were reproduced well for the deep site, but not for the shallow Baltic Sea sites. In the Baltic Sea, the models overmixed the water column after a few days. Vertical temperature diffusivities were higher than those observed and did not show the temporal fluctuations present in the observations. The best performance was by NN and MY; however, MY became unstable in two of the shallow simulations with high winds. The performance of GLS nearly as good as NN and MY. LMD had the poorest performance as it generated temperature diffusivities that were too high and induced too much mixing. Further observational comparisons are needed to evaluate the effects of different stratification and wind conditions and the limitations on the vertical mixing parameterizations.

  3. Use of dihydro-isobenzofuran in combination with serotonin reuptake inhibitors for CNS disease e.g. depression, anxiety, bipolar disorder, obsessive compulsory disorder

    DEFF Research Database (Denmark)

    2013-01-01

    NOVELTY - For treatment of a CNS disease in a patient, dihydro-isobenzofuran compound (I) in combination with serotonin reuptake inhibitor, is used. USE - For treatment of CNS disease (claimed) including depression, anxiety, bipolar disorder, obsessive compulsory disorder, post traumatic stress d...

  4. Mechanical behavior of embankments overlying on loose subgrade stabilized by deep mixed columns

    Directory of Open Access Journals (Sweden)

    Morteza Esmaeili

    2016-10-01

    Full Text Available Deep mixed column (DMC is known as one of the effective methods for stabilizing the natural earth beneath road or railway embankments to control stability and settlements under traffic loads. The load distribution mechanism of embankment overlying on loose subgrades stabilized with DMCs considerably depends on the columns' mechanical and geometrical specifications. The present study uses the laboratory investigation to understand the behavior of embankments lying on loose sandy subgrade in three different conditions: (1 subgrade without reinforcement, (2 subgrade reinforced with DMCs in a triangular pattern and horizontal plan, and (3 subgrade reinforced with DMCs in a square pattern and horizontal plan. For this purpose, by adopting the scale factor of 1:10, a reference embankment with 20 cm height, 250 cm length, and 93% maximum dry density achieved in standard Proctor compaction test was constructed over a 70 cm thick loose sandy bed with the relative density of 50% in a loading chamber, and its load-displacement behavior was evaluated until the failure occurred. In the next two tests, DMCs (with 10 cm diameter, 40 cm length, and 25 cm center-to-center spacing were placed in groups in two different patterns (square and triangular in the same sandy bed beneath the embankment and, consequently, the embankments were constructed over the reinforced subgrades and gradually loaded until the failure happened. In all the three tests, the load-displacement behaviors of the embankment and the selected DMCs were instrumented for monitoring purpose. The obtained results implied 64% increase in failure load and 40% decrease in embankment crest settlement when using the square pattern of DMCs compared with those of the reference embankment, while these values were 63% and 12%, respectively, for DMCs in triangular pattern. This confirmed generally better performance of DMCs with a triangular pattern.

  5. Drama and Theatre in a Nordic Curriculum Perspective--A Challenged Arts Subject Used as a Learning Medium in Compulsory Education

    Science.gov (United States)

    Österlind, Eva; Østern, Anna-Lena; Thorkelsdóttir, Rannveig Björk

    2016-01-01

    The aim of this article is to present a Nordic curriculum perspective on drama and theatre in education ranging from preschool to upper secondary education and cultural schools. Underlined in the Nordic welfare model is an equity, inclusive and democracy perspective, which guarantees free access to compulsory education and to upper secondary…

  6. Experimental observation of strong mixing due to internal wave focusing over sloping terrain

    NARCIS (Netherlands)

    Swart, A.; Manders, A.; Harlander, U.; Maas, L.R.M.

    2010-01-01

    This paper reports on experimental observation of internal waves that are focused due to a sloping topography. A remarkable mixing of the density field was observed. This result is of importance for the deep ocean, where internal waves are believed to play a role in mixing. The experiments were

  7. Gateways and Water Mass Mixing in the Late Cretaceous North Atlantic

    Science.gov (United States)

    Asgharian Rostami, M.; Martin, E. E.; MacLeod, K. G.; Poulsen, C. J.; Vande Guchte, A.; Haynes, S.

    2017-12-01

    Regions of intermediate/deep water formation and water-mass mixing in the North Atlantic are poorly defined for the Late Cretaceous, a time of gateway evolution and cooler conditions following the Mid Cretaceous greenhouse. Improved proxy data combined with modeling efforts are required to effectively evaluate the relationship between CO2, paleogeography, and circulation during this cooler interval. We analyzed and compiled latest Cretaceous (79 - 66 Ma) ɛNd and δ13C records from seven bathyal (paleodepths 0.2 - 2 km) and eight abyssal (paleodepths > 2 km) sites in the North Atlantic. Data suggest local downwelling of Northern Component Water (NCW; ɛNd -9.5 and δ13C 1.7 ‰) is the primary source of intermediate/deep water masses in the basin. As this water flows southward and ages, δ13C values decrease and ɛNd values increase; however, additional chemical changes at several sites require mixing with contributions from several additional water masses. Lower ɛNd ( -10) and higher δ13C ( 1.9 ‰) values in the deep NW part of the basin indicate proximal contributions from a region draining old continental crust, potentially representing deep convection following opening of the Labrador Sea. In the deep NE Iberian Basin, higher ɛNd ( -7) and lower δ13C ( 0.8 ‰) during the Campanian suggest mixing with a Tethyan source (ɛNd -7 and δ13C 0.1 ‰) whose importance decreased with restriction of that gateway in the Maastrichtian. Data from bathyal sites suggest additional mixing. In the SE Cape Verde region, observed ɛNd variations from -10 in the Campanian to -13 and -12 in the early and late Maastrichtian, respectively, may record variations in output rates of Tethyan and/or NCW sources and Demerara Bottom Water (ɛNd -16), a proposed warm saline intermediate water mass formed in shallow, equatorial seas. Pacific inflow through the Caribbean gateway impacts intermediate sites at Blake Nose (ɛNd values -8), particularly the shallowest site during the late

  8. Near-bottom pelagic bacteria at a deep-water sewage sludge disposal site

    Energy Technology Data Exchange (ETDEWEB)

    Takizawa, M.; Straube, W.L.; Hill, R.T.; Colwell, R.R.

    1994-01-01

    The epibenthic bacterial community at deep-ocean sewage sludge disposal site DWD-106, located approximately 106 miles (ca. 196 km) off the coast of New Jersey, was assessed for changes associated with the introduction of large amounts of sewage sludge. Mixed cultures and bacterial isolates obtained from water overlying sediment core samples collected at the deep-water (2,500 m) municipal sewage disposal site were tested for the ability to grow under in situ conditions of temperature and pressure. The responses of cultures collected at a DWD-106 station heavily impacted by sewage sludge were compared with those of samples collected from a station at the same depth which was not contaminated by sewage sludge. Significant differences were observed in the ability of mixed bacterial cultures and isolates from the two sites to grow under deep-sea pressure and temperature conditions. The levels of sludge contamination were established by enumerating Clostridium perfringens, a sewage indicator bacterium, in sediment samples from the two sites. (Copyright (c) 1993, American Society for Microbiology.)

  9. Waste management association with compulsory membership ante portas?

    International Nuclear Information System (INIS)

    Heller, W.

    2004-01-01

    In the course of considerations in the early nineties of reforming atomic energy law, the possibilities was analyzed to privatize the final storage of radioactive waste. One key idea incorporated the finding that the government was of limited usefulness when acting as an entrepreneur, while privatization of this duty could solve the problems associated with planning, building, and operating a repository more speedily and, above all, more economically. In the reform of atomic energy law, final storage remained a government function. The Federal Ministry for the Environment, Nature Conservation, and Nuclear Safety (BMU) is now considering ''reforming the regulations on the final storage of radioactive waste.'' One of the basic ideas underlying this concept is to transfer to an association the site selection, installation, and operation of a repository. The federal government then could limit its functions of those of legal supervision. The upshot would be that the former duties of the federal government of exploring and establishing repositories would be transferred to the association, membership of which would be compulsory and which would have the legal form of a public corporation. A structure of this kind raises a number of organizational and legal problems which are discussed in this contribution. (orig.)

  10. Deep learning enables reduced gadolinium dose for contrast-enhanced brain MRI.

    Science.gov (United States)

    Gong, Enhao; Pauly, John M; Wintermark, Max; Zaharchuk, Greg

    2018-02-13

    There are concerns over gadolinium deposition from gadolinium-based contrast agents (GBCA) administration. To reduce gadolinium dose in contrast-enhanced brain MRI using a deep learning method. Retrospective, crossover. Sixty patients receiving clinically indicated contrast-enhanced brain MRI. 3D T 1 -weighted inversion-recovery prepped fast-spoiled-gradient-echo (IR-FSPGR) imaging was acquired at both 1.5T and 3T. In 60 brain MRI exams, the IR-FSPGR sequence was obtained under three conditions: precontrast, postcontrast images with 10% low-dose (0.01mmol/kg) and 100% full-dose (0.1 mmol/kg) of gadobenate dimeglumine. We trained a deep learning model using the first 10 cases (with mixed indications) to approximate full-dose images from the precontrast and low-dose images. Synthesized full-dose images were created using the trained model in two test sets: 20 patients with mixed indications and 30 patients with glioma. For both test sets, low-dose, true full-dose, and the synthesized full-dose postcontrast image sets were compared quantitatively using peak-signal-to-noise-ratios (PSNR) and structural-similarity-index (SSIM). For the test set comprised of 20 patients with mixed indications, two neuroradiologists scored blindly and independently for the three postcontrast image sets, evaluating image quality, motion-artifact suppression, and contrast enhancement compared with precontrast images. Results were assessed using paired t-tests and noninferiority tests. The proposed deep learning method yielded significant (n = 50, P 5 dB PSNR gains and >11.0% SSIM). Ratings on image quality (n = 20, P = 0.003) and contrast enhancement (n = 20, P deep learning method, gadolinium dose can be reduced 10-fold while preserving contrast information and avoiding significant image quality degradation. 3 Technical Efficacy: Stage 5 J. Magn. Reson. Imaging 2018. © 2018 International Society for Magnetic Resonance in Medicine.

  11. A new approach to irreversibility in deep inelastic collisions

    International Nuclear Information System (INIS)

    Nemes, M.C.

    1982-01-01

    We use concepts of statistical mechanics to discuss the irreversible character of the experimental data in deep inelastic collisions. A definition of irreversibility proposed by Ruch permits a unified overview on current theories which describe these reactions. An information theoretical analysis of the data leads to a Fokker-Planck equation for the collective variables (excitation energy, charge and mass). The concept of mixing distance can serve as a quantitative measure to characterize the 'approach to equilibrium'. We apply it to the brownian motion as an illustration and also to the phenomenological analysis of deep inelastic scattering data with interesting results. (orig.)

  12. Resolving both entrainment-mixing and number of activated CCN in deep convective clouds

    Directory of Open Access Journals (Sweden)

    E. Freud

    2011-12-01

    Full Text Available The number concentration of activated CCN (Na is the most fundamental microphysical property of a convective cloud. It determines the rate of droplet growth with cloud depth and conversion into precipitation-sized particles and affects the radiative properties of the clouds. However, measuring Na is not always possible, even in the cores of the convective clouds, because entrainment of sub-saturated ambient air deeper into the cloud lowers the concentrations by dilution and may cause partial or total droplet evaporation, depending on whether the mixing is homogeneous or extreme inhomogeneous, respectively.

    Here we describe a methodology to derive Na based on the rate of cloud droplet effective radius (Re growth with cloud depth and with respect to the cloud mixing with the entrained ambient air. We use the slope of the tight linear relationship between the adiabatic liquid water mixing ratio and Re3 (or Rv3 to derive an upper limit for Na assuming extreme inhomogeneous mixing. Then we tune Na down to find the theoretical relative humidity that the entrained ambient air would have for each horizontal cloud penetration, in case of homogeneous mixing. This allows us to evaluate both the entrainment and mixing process in the vertical dimension in addition to getting a better estimation for Na.

    We found that the derived Na from the entire profile data is highly correlated with the independent CCN measurements from below cloud base. Moreover, it was found that mixing of sub-saturated ambient air into the cloud at scales of ~100 m and above is inclined towards the extreme inhomogeneous limit, i.e. that the time scale of droplet evaporation is significantly smaller than that for turbulent mixing. This means that ambient air that entrains

  13. Vocations: The Link between Post-Compulsory Education and the Labour Market. What the Research Says For... Tertiary Education Providers & School Educators

    Science.gov (United States)

    Wheelahan, Leesa; Buchanan, John; Yu, Serena

    2015-01-01

    This summary brings together the relevant key findings for tertiary education providers and school educators from the research program "Vocations: The Link between Post-Compulsory Education and the Labour Market." The program was comprised of three different strands: (1) pathways from VET in Schools, (2) pathways within and between…

  14. ASSESSMENT OF EFFECTIVENESS OF TB POSTING DURING THE COMPULSORY ROTATORY RESIDENTIAL INTERNSHIP (CRRI PROGRAMME

    Directory of Open Access Journals (Sweden)

    Pradeep Aggarwal

    2011-12-01

    Full Text Available Research Question: What is the effectiveness of TB posting during the Compulsory Rotatory Residential Internship (CRRI programme? Objectives: To assess the effectiveness of TB posting during the CRRI programme. To find out the need of making Tuberculosis & Respiratory Diseases Department posting mandatory during CRRI Programme. Study Design: Cross Sectional study. Study Duration: 12 months i.e. 01st April 2009 till 31st March 2010 Participants: 90 students who joined the CRRI programme formed the study group. Out of these 90 interns only 57 (64% of them joined their two months Compulsory Rotatory Internship in the Department of Community Medicine and these were posted in Tuberculosis & Respiratory Diseases Department for 15 days. Methodology: A pre-designed pre-tested self-administered questionnaire was administered to the participants on the first day and last day of their posting in Tuberculosis & Respiratory Diseases Department. The results were analysed by using suitable statistical package. Results: The mean pre-test score was 28 (49.6% and the mean post-test score was 38 (61.5%. It was observed that there was a 27% improvement in the knowledge of the participants when the question about the year of launching of RNTCP programme in India was asked. A remarkable improvement (46% was found in the difference between pre and post-test knowledge of the participants when the questions like “Who are the DOTS providers” and “What is the colour coding of boxes for different categories of patients” were asked. A significant difference in the knowledge was found in the pre and post-test assessment in reference to Tuberculosis and its National Programm

  15. Intercomparison of model simulations of mixed-phase clouds observed during the ARM Mixed-Phase Arctic Cloud Experiment. Part II: Multi-layered cloud

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, H; McCoy, R B; Klein, S A; Xie, S; Luo, Y; Avramov, A; Chen, M; Cole, J; Falk, M; Foster, M; Genio, A D; Harrington, J; Hoose, C; Khairoutdinov, M; Larson, V; Liu, X; McFarquhar, G; Poellot, M; Shipway, B; Shupe, M; Sud, Y; Turner, D; Veron, D; Walker, G; Wang, Z; Wolf, A; Xu, K; Yang, F; Zhang, G

    2008-02-27

    Results are presented from an intercomparison of single-column and cloud-resolving model simulations of a deep, multi-layered, mixed-phase cloud system observed during the ARM Mixed-Phase Arctic Cloud Experiment. This cloud system was associated with strong surface turbulent sensible and latent heat fluxes as cold air flowed over the open Arctic Ocean, combined with a low pressure system that supplied moisture at mid-level. The simulations, performed by 13 single-column and 4 cloud-resolving models, generally overestimate the liquid water path and strongly underestimate the ice water path, although there is a large spread among the models. This finding is in contrast with results for the single-layer, low-level mixed-phase stratocumulus case in Part I of this study, as well as previous studies of shallow mixed-phase Arctic clouds, that showed an underprediction of liquid water path. The overestimate of liquid water path and underestimate of ice water path occur primarily when deeper mixed-phase clouds extending into the mid-troposphere were observed. These results suggest important differences in the ability of models to simulate Arctic mixed-phase clouds that are deep and multi-layered versus shallow and single-layered. In general, models with a more sophisticated, two-moment treatment of the cloud microphysics produce a somewhat smaller liquid water path that is closer to observations. The cloud-resolving models tend to produce a larger cloud fraction than the single-column models. The liquid water path and especially the cloud fraction have a large impact on the cloud radiative forcing at the surface, which is dominated by the longwave flux for this case.

  16. Compulsory and recommended vaccination in Italy: evaluation of coverage and non-compliance between 1998-2002 in Northern Italy

    OpenAIRE

    Stampi, Serena; Ricci, Rita; Ruffilli, Isa; Zanetti, Franca

    2005-01-01

    Abstract Background Since vaccinations are an effective prevention tool for maintaining the health of society, the monitoring of immunization coverage allows us to identify areas where disease outbreaks are likely to occur, and possibly assist us in predicting future outbreaks. The aim of this study is the investigation of the coverage achieved for compulsory (diphtheria, tetanus, polio, hepatitis B,) and recommended (pertussis, Haemophilus influenzae, measles-mumps-rubella) vaccinations betw...

  17. Characterization of mixed mode crack opening in concrete

    DEFF Research Database (Denmark)

    Jacobsen, Jonas Sejersbøl; Poulsen, Peter Noe; Olesen, John Forbes

    2012-01-01

    components of the mixed mode displacement are measured using a custom made orthogonal gauge, and the measurements are used directly as the closed loop control signals. A double notch, concrete specimen is used for the crack investigation. The tests are divided into two steps, a pure Mode I opening step......In real concrete structures cracks often open in mixed mode after their initiation. To capture the direct material behavior of a mixed mode crack opening a stiff biaxial testing machine, capable of imposing both normal and shear loads on a given crack area, has been applied. The opening and sliding......, where a macro crack is initiated in the specimen followed by the mixed mode opening step. The high stiffness of the set-up together with the closed control loop ensures a stable crack initiation followed by a controllable mixed mode opening. The deep notches result in a plane crack, only influenced...

  18. Using environmental isotopes along with major hydro-geochemical compositions to assess deep groundwater formation and evolution in eastern coastal China

    Science.gov (United States)

    Xu, Naizheng; Gong, Jianshi; Yang, Guoqiang

    2018-01-01

    Hydrochemical analysis and environmental isotopic tracing are successfully applied to study groundwater evolution processes. Located in eastern China, the Jiangsu Coastal Plain is characterized by an extensively exploited deep groundwater system, and groundwater salinization has become the primary water environmental problem. This paper provides a case study on the use of a hydrochemical and environmental isotopic approach to assess possible mixing and evolution processes at Yoco Port, Jiangsu Province, China. Hydrochemical and isotopic patterns of deep groundwater allow one to distinguish different origins in deep water systems. HCO3- is the dominant anion in the freshwater samples, whereas Na+ and Cl- are the dominant major ions in the saline samples. According to δ18O, δ2H and 14C dating, the fresh water is derived from precipitation under a colder climate during the Glacial Maximum (Dali Glacial), while the saline groundwater is influenced by glacial-interglacial cycles during the Holocene Hypsithermal. The δ18O, δ2H and 3H data confirm that deep groundwater in some boreholes is mixed with overlying saline water. The deep groundwater reservoir can be divided into a saline water sector and a fresh water sector, and each show distinct hydrochemical and isotopic compositions. The saline groundwater found in the deep aquifer cannot be associated with present seawater intrusion. Since the Last Glacial Maximum in the Late Pleistocene, the deep groundwater flow system has evolved to its current status with the decrease in ice cover and the rising of sea level. However, the hydraulic connection is strengthened by continuous overexploitation, and deep groundwater is mixed with shallow groundwater at some points.

  19. The five-year costs and benefits of extended psychological and psychiatric assessment versus standard intake interview for women with comorbid substance use disorders treated in compulsory care in Sweden.

    Science.gov (United States)

    Olsson, Tina M; Fridell, Mats

    2018-01-30

    Women with comorbid substance use disorders are an extremely vulnerable group having an increased relative risk of negative outcomes such as incarceration, morbidity and mortality. In Sweden, women with comorbid substance use disorders may be placed in compulsory care for substance abuse treatment. Clinical intake assessment procedures are a distinct aspect of clinical practice and are a foundation upon which client motivation and continued treatment occurs. The current study is a naturalistic quasi-experiment and aims to assess the five-year costs and benefits of a standard intake interview versus an extended psychological and psychiatric assessment for a group of chronic substance abusing women placed in compulsory care in Sweden between 1997 and 2000. Official register data on criminal activity, healthcare use, compulsory care stays and other services was retrieved and all resources used by study participants from date of index care episode was valued. In addition, the cost of providing the intake assessment was estimated. Results show that the extended assessment resulted in higher net costs over five years of between 256,000 and 557,000 SEK per person for women placed in care via the Law on Compulsory Care for Substance Abusers (LVM). Higher assessment costs made up a portion of this cost. The majority of this cost (47-57%) falls on the local municipality (social welfare) and 11.6-13.7% falls on the individual patient. Solid evidence supporting the clinical utility or incremental validity of assessment for improving treatment outcomes in this setting was not confirmed.

  20. DeepPy: Pythonic deep learning

    DEFF Research Database (Denmark)

    Larsen, Anders Boesen Lindbo

    This technical report introduces DeepPy – a deep learning framework built on top of NumPy with GPU acceleration. DeepPy bridges the gap between highperformance neural networks and the ease of development from Python/NumPy. Users with a background in scientific computing in Python will quickly...... be able to understand and change the DeepPy codebase as it is mainly implemented using high-level NumPy primitives. Moreover, DeepPy supports complex network architectures by letting the user compose mathematical expressions as directed graphs. The latest version is available at http...

  1. Deep water overflow in the Faroe Bank Channel; modelling, processes, and impact

    DEFF Research Database (Denmark)

    Rullyanto, Arief

    , creating new water masses with distinct temperature, salinity and density characteristics. The change of water mass characteristics not only affects the local environment, but also far distant regions. The Faroe Bank Channel, which is located in the southern part of Faroe Islands, is one of the most...... under different circumstances. The focus is on the Faroe Bank Channel, a relatively small region, which has a significant impact on the global ocean circulation and marine organisms that live in its environment....... or tides, but also deep beneath the surface, where deep-water currents circulate waters throughout the world’s oceans. In certain very-localized regions, the flow of the deep-water has to travel over a sill in a narrow submarine channel. This overflow process mixes the deep water with overlying waters...

  2. Hot-spot mix in ignition-scale inertial confinement fusion targets.

    Science.gov (United States)

    Regan, S P; Epstein, R; Hammel, B A; Suter, L J; Scott, H A; Barrios, M A; Bradley, D K; Callahan, D A; Cerjan, C; Collins, G W; Dixit, S N; Döppner, T; Edwards, M J; Farley, D R; Fournier, K B; Glenn, S; Glenzer, S H; Golovkin, I E; Haan, S W; Hamza, A; Hicks, D G; Izumi, N; Jones, O S; Kilkenny, J D; Kline, J L; Kyrala, G A; Landen, O L; Ma, T; MacFarlane, J J; MacKinnon, A J; Mancini, R C; McCrory, R L; Meezan, N B; Meyerhofer, D D; Nikroo, A; Park, H-S; Ralph, J; Remington, B A; Sangster, T C; Smalyuk, V A; Springer, P T; Town, R P J

    2013-07-26

    Mixing of plastic ablator material, doped with Cu and Ge dopants, deep into the hot spot of ignition-scale inertial confinement fusion implosions by hydrodynamic instabilities is diagnosed with x-ray spectroscopy on the National Ignition Facility. The amount of hot-spot mix mass is determined from the absolute brightness of the emergent Cu and Ge K-shell emission. The Cu and Ge dopants placed at different radial locations in the plastic ablator show the ablation-front hydrodynamic instability is primarily responsible for hot-spot mix. Low neutron yields and hot-spot mix mass between 34(-13,+50)  ng and 4000(-2970,+17 160)  ng are observed.

  3. Moisture Vertical Structure, Deep Convective Organization, and Convective Transition in the Amazon

    Science.gov (United States)

    Schiro, K. A.; Neelin, J. D.

    2017-12-01

    Constraining precipitation processes in climate models with observations is crucial to accurately simulating current climate and reducing uncertainties in future projections. Results from the Green Ocean Amazon (GOAmazon) field campaign (2014-2015) provide evidence that deep convection is strongly controlled by the availability of moisture in the free troposphere over the Amazon, much like over tropical oceans. Entraining plume buoyancy calculations confirm that CWV is a good proxy for the conditional instability of the environment, yet differences in convective onset as a function of CWV exist over land and ocean, as well as seasonally and diurnally over land. This is largely due to variability in the contribution of lower tropospheric humidity to the total column moisture. Boundary layer moisture shows a strong relationship to the onset during the day, which largely disappears during nighttime. Using S-Band radar, these transition statistics are examined separately for unorganized and mesoscale-organized convection, which exhibit sharp increases in probability of occurrence with increasing moisture throughout the column, particularly in the lower free troposphere. Retrievals of vertical velocity from a radar wind profiler indicate updraft velocity and mass flux increasing with height through the lower troposphere. A deep-inflow mixing scheme motivated by this — corresponding to deep inflow of environmental air into a plume that grows with height — provides a weighting of boundary layer and free tropospheric air that yields buoyancies consistent with the observed onset of deep convection across seasons and times of day, across land and ocean sites, and for all convection types. This provides a substantial improvement relative to more traditional constant mixing assumptions, and a dramatic improvement relative to no mixing. Furthermore, it provides relationships that are as strong or stronger for mesoscale-organized convection as for unorganized convection.

  4. Processes governing transient responses of the deep ocean buoyancy budget to a doubling of CO2

    Science.gov (United States)

    Palter, J. B.; Griffies, S. M.; Hunter Samuels, B. L.; Galbraith, E. D.; Gnanadesikan, A.

    2012-12-01

    Recent observational analyses suggest there is a temporal trend and high-frequency variability in deep ocean buoyancy in the last twenty years, a phenomenon reproduced even in low-mixing models. Here we use an earth system model (GFDL's ESM2M) to evaluate physical processes that influence buoyancy (and thus steric sea level) budget of the deep ocean in quasi-steady state and under a doubling of CO2. A new suite of model diagnostics allows us to quantitatively assess every process that influences the buoyancy budget and its temporal evolution, revealing surprising dynamics governing both the equilibrium budget and its transient response to climate change. The results suggest that the temporal evolution of the deep ocean contribution to sea level rise is due to a diversity of processes at high latitudes, whose net effect is then advected in the Eulerian mean flow to mid and low latitudes. In the Southern Ocean, a slowdown in convection and spin up of the residual mean advection are approximately equal players in the deep steric sea level rise. In the North Atlantic, the region of greatest deep steric sea level variability in our simulations, a decrease in mixing of cold, dense waters from the marginal seas and a reduction in open ocean convection causes an accumulation of buoyancy in the deep subpolar gyre, which is then advected equatorward.

  5. The political and scientific challenges in evaluating compulsory drug treatment centers in Southeast Asia.

    Science.gov (United States)

    Vuong, Thu; Nguyen, Nhu; Le, Giang; Shanahan, Marian; Ali, Robert; Ritter, Alison

    2017-01-11

    In Vietnam, like many countries in Southeast Asia, the commonly used approach of center-based compulsory drug treatment (CCT) has been criticized on human rights ground. Meanwhile, community-based voluntary methadone maintenance treatment (MMT) has been implemented for nearly a decade with promising results. Reform-minded leaders have been seeking empirical evidence of the costs and effectiveness associated with these two main treatment modalities. Conducting evaluations of these treatments, especially where randomization is not ethical, presents challenges. The aim of this paper is to discuss political challenges and methodological issues when conducting cost-effectiveness studies within the context of a non-democratic Southeast Asian country. A retrospective analysis of the political and scientific challenges that were experienced in the study design, sample size determination, government approval and ethics approvals, participant recruitment, data collection, and determination of sources, and quantification of cost and effectiveness data was undertaken. As a consequence of the non-randomized design, analysis of patient characteristics for both treatment types was undertaken to identify the magnitude of baseline group differences. Concordance between self-reported heroin use and urine drug testing was undertaken to determine the reliability of self-report data in a politically challenging environment. We demonstrate that conducting research around compulsory treatment in a non-democratic society is feasible, yet it is politically challenging and requires navigation between science and politics. We also demonstrate that engagement with the government decision makers in the research conception, implementation, and dissemination of the results increases the likelihood of research evidence being considered for change in a contentious drug policy area. Local empirical evidence on the comparative cost-effectiveness of CCT and MMT in a Southeast Asian setting is

  6. After compulsory licensing: coming issues in Canadian pharmaceutical policy and politics.

    Science.gov (United States)

    Lexchin, J

    1997-04-01

    Bills C-22 and C-91 eliminated compulsory licensing for pharmaceutical products in Canada. However, in the wake of these bills there are pressing issues of pharmaceutical policy that need to be decided. The value of additional spending in pharmaceutical R and D has yet to be evaluated. There needs to be a public debate about how far government policy should go in encouraging pharmaceutical R and D as opposed to investing resources in other areas. There has been a continuing escalation in the cost of the average prescription, due to the introduction of newer, but not necessarily more effective, medications. So far government has not been willing to commit resources to promote cost-effective prescribing. Pharmaceutical companies are now lobbying for more rapid approval of products and an extension to the normal patent period to make up for the time that drugs spend in the regulatory process. The process that the government uses to resolve these issues will be just as important as the ultimate decisions.

  7. Chemical stratigraphy of the Apollo 17 deep drill cores 70009-70007

    Science.gov (United States)

    Ehmann, W. D.; Ali, M. Z.

    1977-01-01

    A description is presented of an analysis of a total of 26 samples from three core segments (70009, 70008, 70007) of the Apollo 17 deep drill string. The deep drill string was taken about 700 m east of the Camelot Crater in the Taurus-Littrow region of the moon. Three core segments have been chemically characterized from the mainly coarse-grained upper portion of the deep drill string. The chemical data suggest that the entire 70007-70009 portion of the deep drill string examined was not deposited as a single unit, but was formed by several events sampling slightly different source materials which may have occurred over a relatively short period of time. According to the data from drill stem 70007, there were at least two phases of deposition. Core segment 70009 is probably derived from somewhat different source material than 70008. It seems to be a very well mixed material.

  8. A Methodology for Conducting Integrative Mixed Methods Research and Data Analyses

    Science.gov (United States)

    Castro, Felipe González; Kellison, Joshua G.; Boyd, Stephen J.; Kopak, Albert

    2011-01-01

    Mixed methods research has gained visibility within the last few years, although limitations persist regarding the scientific caliber of certain mixed methods research designs and methods. The need exists for rigorous mixed methods designs that integrate various data analytic procedures for a seamless transfer of evidence across qualitative and quantitative modalities. Such designs can offer the strength of confirmatory results drawn from quantitative multivariate analyses, along with “deep structure” explanatory descriptions as drawn from qualitative analyses. This article presents evidence generated from over a decade of pilot research in developing an integrative mixed methods methodology. It presents a conceptual framework and methodological and data analytic procedures for conducting mixed methods research studies, and it also presents illustrative examples from the authors' ongoing integrative mixed methods research studies. PMID:22167325

  9. Mixing and its effects on biogeochemistry in the persistently stratified, deep, tropical Lake Matano, Indonesia

    DEFF Research Database (Denmark)

    Katsev, Sergei; Crowe, Sean; Mucci, Alfonso

    2010-01-01

    In the > 590-m deep, tropical Lake Matano (Indonesia), stratification is characterized by weak thermal gradients (... steady-state conditions, vertical eddy diffusion coefficients (K-z) cannot be estimated by conventional methods that rely on time derivatives of temperature distributions. We use and compare several alternative methods: one-dimensional k-epsilon modeling, three-dimensional hydrodynamic modeling...... composition in the deep waters is close to those of the ground and tributary waters. The vertical distribution of K-z is used in a biogeochemical reaction-transport model. We show that, outside of a narrow thermocline region, the vertical distributions of dissolved oxygen, iron, methane, and phosphorus...

  10. ON THE NEED FOR DEEP-MIXING IN ASYMPTOTIC GIANT BRANCH STARS OF LOW MASS

    International Nuclear Information System (INIS)

    Busso, M.; Palmerini, S.; Maiorca, E.; Cristallo, S.; Abia, C.; Straniero, O.; Gallino, R.; Cognata, M. La

    2010-01-01

    The photospheres of low-mass red giants show CNO isotopic abundances that are not satisfactorily accounted for by canonical stellar models. The same is true for the measurements of these isotopes and of the 26 Al/ 27 Al ratio in presolar grains of circumstellar origin. Non-convective mixing, occurring during both red giant branch (RGB) and asymptotic giant branch (AGB) stages, is the explanation commonly invoked to account for the above evidence. Recently, the need for such mixing phenomena on the AGB was questioned, and chemical anomalies usually attributed to them were suggested to be formed in earlier phases. We have therefore re-calculated extra-mixing effects in low-mass stars for both the RGB and AGB stages, in order to verify the above claims. Our results contradict them; we actually confirm that slow transport below the convective envelope occurs also on the AGB. This is required primarily by the oxygen isotopic mix and the 26 Al content of presolar oxide grains. Other pieces of evidence exist, in particular from the isotopic ratios of carbon stars of type N, or C(N), in the Galaxy and in the LMC, as well as of SiC grains of AGB origin. We further show that, when extra-mixing occurs in the RGB phases of Population I stars above about 1.2 M sun , this consumes 3 He in the envelope, probably preventing the occurrence of thermohaline diffusion on the AGB. Therefore, we argue that other extra-mixing mechanisms should be active in those final evolutionary phases.

  11. Schools That Make a Difference to Post-Compulsory Uptake of Physical Science Subjects: Some comparative case studies in England

    Science.gov (United States)

    Bennett, Judith; Lubben, Fred; Hampden-Thompson, Gillian

    2013-03-01

    This paper presents the findings of the qualitative component of a combined methods research study that explores a range of individual and school factors that influence the uptake of chemistry and physics in post-compulsory study in England. The first phase involves using the National Pupil Database to provide a sampling frame to identify four matched pairs of high-uptake and low-uptake schools by salient school factors. Case studies of these eight schools indicate that students employ selection strategies related to their career aspirations, their sense of identity and tactics, and their prior experience. The school factors influencing subject choice relate to school management, student support and guidance, and student empowerment. The most notable differences between students in high-uptake and low-uptake schools are that students in high-uptake schools appear to make a proactive choice in relation to career aspirations, rather than a reactive choice on the basis of past experience. Schools with a high uptake offer a diverse science curriculum in the final two years of compulsory study, set higher examination entry requirements for further study and, crucially, provide a range of opportunities for students to interact with the world of work and to gain knowledge and experience of science-related careers.

  12. Evaluating the Comparability of PPT and CBT by Implementing the Compulsory Islamic Culture Course Test in Jordan University

    Directory of Open Access Journals (Sweden)

    Abdelnaser Sanad Alakyleh

    2017-12-01

    Full Text Available Study aims to determine whether the university students' scores in the compulsory Islamic culture course test on a selected sample differ across the paper-and pencil test (PPT & computer-based test (CBT versions, and to reveal the relationship between gender and the student's level of performance in the test. Therefore, the study evaluated the comparability of two versions of a compulsory Islamic culture course test (PPTs and (CBTs. The importance of conducting the study in Jordan stems from the fact that public and private universities have begun to move away from the traditional patterns of tests such (PPTs and went towards (CBTs. In addition to detecting which model gives the best in the output and has the characteristics of the psychometric test, furthermore, indicates whether there were any differences between males and females, the study sample consisted of 120 individuals, 67 females and 53 males from scientific, health and humanities colleges. The results showed that there was no significant difference between the two versions provided to students CBT and PPT with 0.36 moderate correlation indicators in the pre-CBT test, no significant differences between the males and females in the CBT test results. Therefore, on the basis of the results of the present study, the CBT test is an option and a preferred alternative for regular students of the bachelor's level at the University of Jordan.

  13. Injection grout for deep repositories. Subproject 1: LowpH cementitious grout for larger fractures, leach testing of grout mixes and evaluation of the long-term safety

    International Nuclear Information System (INIS)

    Vuorinen, U.; Lehikoinen, J.; Imoto, Harutake; Yamamoto, Takeshi; Cruz Alonso, M.

    2005-10-01

    Constructing an underground disposal facility for spent nuclear fuel deep in bedrock requires lowpH cement-based injection grout, because assured data of the extent of a possible high-pH plume in saturated bedrock conditions is lacking. In this work low-pH grout mixes of new design were subjected to leach testing. Before chosen to leach testing the grout mixes had to fulfil certain technical requirements. Leach testing was performed in order to establish that the pH requirement (≤11) set for the leachates was met. For comparison reasons also one conventionally used cement based grout material was included in the tests. Two kinds of lowpH grout cement mixes were tested; mixes with added blast furnace slag (4 mixes) or added silica (6 mixes). All the mixes were not completely tested according to the test plan, because for some mixes during leach testing factors detrimental to the long-term safety of a repository were observed, e.g. too high pH or leached sulphide, which is harmful for copper. Leach testing of the grout mixes was performed in a glove-box (N 2 atmosphere) in order to avoid the interference of atmospheric CO 2 on the alkaline leachates. Two simulated groundwater solutions, saline OL-SO and fresh ALL-MR, were used as leachates. Two leach tests were applied; equilibrium and diffusion tests. In the equilibrium test at each measuring point only a part of the leachate was exchanged, whereas in the diffusion test the entire leachate was exchanged. The pH value of each leachate sample was measured, but total alkalinity was determined only for some leachates. Na, K, Ca, Mg, Al, Fe, Si, SO 4 2- , S TOT , and Cl were analysed in the leach solutions collected in the diffusion test of four grout mixes chosen. Also the corresponding solid specimens were analysed (SEM, XRD, EPMA, MIP, TG) in Japan. A few grout pore fluid pH values were measured in Spain, as well. The simplified thermodynamic model calculations were successful in qualitatively reproducing the

  14. Monitoring of Deep Foundation Pit Support and Construction Process in Soft Soil Area of Pearl River Delta

    Science.gov (United States)

    Weiyi, Xie; Pengcheng

    2018-03-01

    The deep foundation pit supporting technology in the soft soil area of the Pearl River Delta is more complicated, and many factors influence and restrict it. In this project as an example, according to the geological conditions and the surrounding circumstances, the main foundation using bored piles and pre-stressed anchor cable supporting structure + five axis cement mixing pile curtain supporting form; partial use of double row piles supporting structure + five axis cement mixing pile curtain support type. Through the monitoring results of construction show that the foundation pit, the indicators of environmental changes are in the design range, the supporting scheme of deep foundation pit technology is feasible and reliable.

  15. Modification of deep waters in Marguerite Bay, western Antarctic Peninsula, caused by topographic overflows

    Science.gov (United States)

    Venables, Hugh J.; Meredith, Michael P.; Brearley, J. Alexander

    2017-05-01

    Circumpolar Deep Water (CDW) intrudes from the mid-layers of the Antarctic Circumpolar Current onto the shelf of the western Antarctic Peninsula, providing a source of heat and nutrients to the regional ocean. It is well known that CDW is modified as it flows across the shelf, but the mechanisms responsible for this are not fully known. Here, data from underwater gliders with high spatial resolution are used to demonstrate the importance of detailed bathymetry in inducing multiple local mixing events. Clear evidence for overflows is observed in the glider data as water flows along a deep channel with multiple transverse ridges. The ridges block the densest waters, with overflowing water descending several hundred metres to fill subsequent basins. This vertical flow leads to entrainment of overlying colder and fresher water in localised mixing events. Initially this process leads to an increase in bottom temperatures due to the temperature maximum waters descending to greater depths. After several ridges, however, the mixing is sufficient to remove the temperature maximum completely and the entrainment of colder thermocline waters to depth reduces the bottom temperature, to approximately the same as in the source region of Marguerite Trough. Similarly, it is shown that deep waters of Palmer Deep are warmer than at the same depth at the shelf break. The exact details of the transformations observed are heavily dependent on the local bathymetry and water column structure, but glacially-carved troughs and shallow sills are a common feature of the bathymetry of polar shelves, and these types of processes may be a factor in determining the hydrographic conditions close to the coast across a wider area.

  16. The abyssal and deep circulation of the Northeast Pacific Basin

    Science.gov (United States)

    Hautala, Susan L.

    2018-01-01

    Three-dimensional abyssal and deep circulation of the region to the east and north of the Emperor Seamount Chain/Hawaiian Ridge is determined from a compilation of CTD and Argo float data, using a new overdetermined inverse technique for the geostrophic reference velocity and diapycnal/lateral mixing coefficients. The Northeast Pacific Basin is primarily sourced from its northern boundary, at a rate of 3.5 Sv across 47°N below 3000 m. Bottom water in the western subarctic gyre recirculates cyclonically between the Emperor Seamount Chain and 155°W. Bottom water east of 155°W takes a more direct path southward along the flank of a broad topographic slope. In the deep water, a ridge of potential vorticity lying along the Mendocino Fracture Zone separates circulation systems north and south of ∼40°N. The region has very weak diapycnal and lateral mixing, and an aspect ratio for the overturning circulation that is correspondingly flat, with bottom water parcels rising less than 1 km during their long transit from the Aleutian Trench to the latitude of Hawaii.

  17. MANAGEMENT ACCOUNTING SYSTEM OF PUBLIC OFF-BUDGET FUNDS AS AN INFORMATIONAL BASIS FOR PUBLIC INSURANCE MECHANISMS FORMATION (CASE STUDY OF FEDERAL COMPULSORY MEDICAL INSURANCE FUND

    Directory of Open Access Journals (Sweden)

    Anatoly A. Kozlov

    2014-01-01

    Full Text Available The article justifies the introduced proposals for a management accounting of theFederal Compulsory Medical InsuranceFund formation and the characteristics and principles of management accounting forms for the analysis of the territorialcompulsory medical insurance programs.

  18. Photoemission studies of mixed valent systems

    International Nuclear Information System (INIS)

    Parks, R.D.; Raaen, S.; denBoer, M.L.; Williams, G.P.

    1984-01-01

    Photoemission spectroscopy has been used to study a number of aspects of the mixed valent state (corresponding to non-integral 4f occupation) in rare earth systems. Deep core photoemission (e.g., from 3d or 4d levels) allows the measurement of the 4f occupancy and surface valence shifts, and, as well, the indirect measurement of the effect of solid state environment on the energy of hybridization between 4f electrons and conduction electrons. 4f-Derived photoemission has been used to study surface valance and chemical shifts and to infer the nature of the mixed valent ground state. A combination of 4f-derived photoemission and add-electron spectroscopy provides a measurement of the rf Coulomb correlation energy, an important parameter in the mixed valent problem. A review of these approaches will be presented, with emphasis on Ce-based systems, whose behavior falls outside the usual description of 4f-unstable systems

  19. Climatology and evolution of the mixing height over water

    Energy Technology Data Exchange (ETDEWEB)

    Sempreviva, A.M. [Istituto di Fisica dell`Atmosfera, CNR, Rome (Italy); Grynig, S.E. [Risoe National Lab., Roskilde (Denmark)

    1997-10-01

    In this paper we present results from an experimental investigation on the height of the mixed layer h, using a meteorological station located on the Danish island of Anholt. The station was operational for two years from September 1990 to October 1992. We present the analysis of two years of radio-sounding showing the average daily evolution of h. Furthermore observations of the mixed layer growth under near-neutral and unstable atmospheric conditions during six consecutive days has been modelled using a simple zero-order mixed-layer height model. Finally we have compared the evolution of the mixing height from the model with the evolution of the correlation coefficient between temperature and humidity to study the influence of the deepness of the convective layer on the mechanism of the correlation between temperature and humidity in the surface layer. (au)

  20. Mixed-Reality Prototypes to Support Early Creative Design

    Science.gov (United States)

    Safin, Stéphane; Delfosse, Vincent; Leclercq, Pierre

    The domain we address is creative design, mainly architecture. Rooted in a multidisciplinary approach as well as a deep understanding of architecture and design, our method aims at proposing adapted mixed-reality solutions to support two crucial activities: sketch-based preliminary design and distant synchronous collaboration in design. This chapter provides a summary of our work on a mixed-reality device, based on a drawing table (the Virtual Desktop), designed specifically to address real-life/business-focused issues. We explain our methodology, describe the two supported activities and the related users’ needs, detail the technological solution we have developed, and present the main results of multiple evaluation sessions. We conclude with a discussion of the usefulness of a profession-centered methodology and the relevance of mixed reality to support creative design activities.

  1. Forecasting the evolution in the mixing regime of a deep subalpine lake under climate change scenarios through numerical modelling (Lake Maggiore, Northern Italy/Southern Switzerland)

    Science.gov (United States)

    Fenocchi, Andrea; Rogora, Michela; Sibilla, Stefano; Ciampittiello, Marzia; Dresti, Claudia

    2018-01-01

    The impact of air temperature rise is eminent for the large deep lakes in the Italian subalpine district, climate change being caused there by both natural phenomena and anthropogenic greenhouse-gases (GHG) emissions. These oligomictic lakes are experiencing a decrease in the frequency of winter full turnover and an intensification of stability. As a result, hypolimnetic oxygen concentrations are decreasing and nutrients are accumulating in bottom water, with effects on the whole ecosystem functioning. Forecasting the future evolution of the mixing pattern is relevant to assess if a reduction in GHG releases would be able to revert such processes. The study focuses on Lake Maggiore, for which the thermal structure evolution under climate change in the 2016-2085 period was assessed through numerical simulations, performed with the General Lake Model (GLM). Different prospects of regional air temperature rise were considered, given by the Swiss Climate Change Scenarios CH2011. Multiple realisations were performed for each scenario to obtain robust statistical predictions, adopting random series of meteorological data produced with the Vector-Autoregressive Weather Generator (VG). Results show that a reversion in the increasing thermal stability would be possible only if global GHG emissions started to be reduced by 2020, allowing an equilibrium mixing regime to be restored by the end of the twenty-first century. Otherwise, persistent lack of complete-mixing, severe water warming and extensive effects on water quality are to be expected for the centuries to come. These projections can be extended to the other lakes in the subalpine district.

  2. Nondestructive evaluation of differently doped InP wafers by time-resolved four-wave mixing technique

    International Nuclear Information System (INIS)

    Kadys, A.; Sudzius, M.; Jarasiunas, K.; Mao Luhong; Sun Niefeng

    2006-01-01

    Photoelectric properties of semi-insulating, differently doped, and undoped indium phosphide wafers, grown by the liquid encapsulation Czochralski method, have been investigated by time-resolved picosecond four-wave mixing technique. Deep defect related carrier generation, recombination, and transport properties were investigated experimentally by measuring four-wave mixing kinetics and exposure characteristics. The presence of deep donor states in undoped InP was confirmed by a pronounced effect of a space charge electric field to carrier transport. On the other hand, the recharging dynamics of electrically active residual impurities was observed in undoped and Fe-doped InP through the process of efficient trapping of excess carriers. The bipolar diffusion coefficients and mobilities were determined for the all wafers

  3. Event-Driven Random Back-Propagation: Enabling Neuromorphic Deep Learning Machines.

    Science.gov (United States)

    Neftci, Emre O; Augustine, Charles; Paul, Somnath; Detorakis, Georgios

    2017-01-01

    An ongoing challenge in neuromorphic computing is to devise general and computationally efficient models of inference and learning which are compatible with the spatial and temporal constraints of the brain. One increasingly popular and successful approach is to take inspiration from inference and learning algorithms used in deep neural networks. However, the workhorse of deep learning, the gradient descent Gradient Back Propagation (BP) rule, often relies on the immediate availability of network-wide information stored with high-precision memory during learning, and precise operations that are difficult to realize in neuromorphic hardware. Remarkably, recent work showed that exact backpropagated gradients are not essential for learning deep representations. Building on these results, we demonstrate an event-driven random BP (eRBP) rule that uses an error-modulated synaptic plasticity for learning deep representations. Using a two-compartment Leaky Integrate & Fire (I&F) neuron, the rule requires only one addition and two comparisons for each synaptic weight, making it very suitable for implementation in digital or mixed-signal neuromorphic hardware. Our results show that using eRBP, deep representations are rapidly learned, achieving classification accuracies on permutation invariant datasets comparable to those obtained in artificial neural network simulations on GPUs, while being robust to neural and synaptic state quantizations during learning.

  4. Event-Driven Random Back-Propagation: Enabling Neuromorphic Deep Learning Machines

    Directory of Open Access Journals (Sweden)

    Emre O. Neftci

    2017-06-01

    Full Text Available An ongoing challenge in neuromorphic computing is to devise general and computationally efficient models of inference and learning which are compatible with the spatial and temporal constraints of the brain. One increasingly popular and successful approach is to take inspiration from inference and learning algorithms used in deep neural networks. However, the workhorse of deep learning, the gradient descent Gradient Back Propagation (BP rule, often relies on the immediate availability of network-wide information stored with high-precision memory during learning, and precise operations that are difficult to realize in neuromorphic hardware. Remarkably, recent work showed that exact backpropagated gradients are not essential for learning deep representations. Building on these results, we demonstrate an event-driven random BP (eRBP rule that uses an error-modulated synaptic plasticity for learning deep representations. Using a two-compartment Leaky Integrate & Fire (I&F neuron, the rule requires only one addition and two comparisons for each synaptic weight, making it very suitable for implementation in digital or mixed-signal neuromorphic hardware. Our results show that using eRBP, deep representations are rapidly learned, achieving classification accuracies on permutation invariant datasets comparable to those obtained in artificial neural network simulations on GPUs, while being robust to neural and synaptic state quantizations during learning.

  5. Waste disposal in the deep ocean: An overview

    International Nuclear Information System (INIS)

    O'Connor, T.P.; Kester, D.R.; Burt, W.V.; Capuzzo, J.M.; Park, P.K.; Duedall, I.W.

    1985-01-01

    Incineration at sea, industrial and sewage waste disposal in the surface mixing zone, and disposal of low-level nuclear wastes, obsolete munitions, and nerve gas onto the seafloor have been the main uses of the deep sea for waste management. In 1981 the wastes disposed of in the deep sea consisted of 48 X 10/sup 4/ t of liquid industrial wastes and 2 X 10/sup 4/ t of sewage sludge by the United States; 1.5 X 10/sup 4/ t (solids) of sewage sludge by the Federal Republic of German; 5300 t of liquid industrial wastes by Denmark; 99 t of solid industrial wastes by the United Kingdom; and 9400 t of low-level radioactive wastes by several European countries. Also in 1981 at-sea incineration of slightly more than 10/sup 5/ t of organic wastes from Belgium, France, the Federal Republic of Germany, the Netherlands, Norway, Sweden, and the United Kingdom was carried out in the North Sea. Unique oceanographic features of the deep sea include its large dilution capacity; the long residence time of deep-sea water (on the order of 10/sup 2/ y); low biological productivity in the surface water of the open ocean (≅50 g m/sup -2/ of carbon per year); the existence of an oxygen minimum zone at several hundred meters deep in the mid-latitudes; and the abyssal-clay regions showing sedimentary records of tens of millions of years of slow, uninterrupted deposition of fine-grained clay. Any deep-sea waste disposal strategy must take into account oceanic processes and current scientific knowledge in order to attain a safe solution that will last for centuries

  6. Mechanisms of hypolimnion erosion in a deep lake (Lago Maggiore, N. Italy

    Directory of Open Access Journals (Sweden)

    Elisabetta A. CARRARA

    2010-02-01

    Full Text Available Holo-oligomixis is one of the most important hydrodynamic characteristics of deep lakes in temperate regions, especially those of the Southern Alps. It influences such important lake chemical and biological processes as the oxygenation of deep layers, recycling of nutrients, vertical migration of plankton, and reproduction. Analysis of physico-chemical data from Lago Maggiore over the years 1951 – 2008 has shown that in addition to ever active but relatively inefficient convective mixing, three other mechanisms act to oxygenate this lake’s deep waters in winter. These are conveyor belt currents, cold and well-oxygenated tributary inflows that sink down to depths of equal density, and differential cooling of littoral waters that subsequently slide down the lake flanks. Their common outcome is to cause deep erosion of the hypolimnion. Heat content and thermal stability also are affected and are analyzed here in relation to external driving forces, examining in particular how dynamics may be altered by climate change.

  7. "A Place Where Open Minds Meet": The Constraints of Alignment and the Effects of Compulsory Teacher Training on Teaching and Learning in Higher Education

    Science.gov (United States)

    Mihailova, Paulina

    2014-01-01

    The article investigates how university lecturers taking part in the compulsory teacher training at Stockholm University (SU) conceive of the effects of standardised and formalised training on their teaching. The study explores the emotions and responses evoked among academics when everyone is required to embrace the same pedagogic philosophy of…

  8. Geochemical evidence for groundwater mixing in the western Great Artesian Basin and recognition of deep inputs in continental-scale flow systems

    Science.gov (United States)

    Crossey, L. J.; Karlstrom, K. E.; Love, A.; Priestley, S.; Shand, P.

    2010-12-01

    Hot Springs record different degrees of fluid-rock interactions in granitic crust and small volume, but geochemically potent, crustal contributions to the endogenic fluids. U-Series dates indicate persistent deposition of travertine mound springs (conceptualized as “chemical volcanoes”) at discrete vent sites for millions of years. The geochemistry of the active travertine-depositing mound springs, coupled with geochemistry of the associated mound and platform travertine rock record, thus collectively provide a rich record that can be used to link the present hydrologic system to paleohydrology of the GAB over the last several million years at the continental scale. The overall goal is to test a model for interactions between mantle and deep crustal fluid inputs, neotectonic pathways, groundwater mixing, groundwater quantity and quality, and unique microbiology in the near-surface hydrologic systems.

  9. [Experience feed back committee in radiotherapy (CREx): a compulsory tool for security management evaluation at two years].

    Science.gov (United States)

    Lartigau, E; Coche-Dequeant, B; Dumortier, V; Giscard, S; Lacornerie, T; Lasue, A; Cheval, V; Martel, V; Malfait, B; Fuchs, A; Pestel, M; Damman, M; Forrest, M

    2008-11-01

    After working on treatment organisation in radiotherapy (bonne pratiques organisationnelles en radiothérapie - action pilote MEAH 2003), the development of a security policy has become crucial. With the help of Air France Consulting and the MEAH, three cancer centers in Angers, Lille and Villejuif worked together on the implantation of experience feed back committees (CREx) dedicated to the registration, analysis and correction of precursor events. After two years, we report the centre Oscar-Lambret experience in Lille and try to get the recommendations for generalisation of the process. This seems now to be compulsory for security management in oncology.

  10. Temperature, heat content, mixing and stability in Lake Orta: a pluriannual investigation

    Directory of Open Access Journals (Sweden)

    Luigi BARBANTI

    2001-02-01

    Full Text Available This paper describes the overall state of some physical phenomena occurring in Lake Orta, such as thermal stratification and destratification, accumulation and release of heat, vertical winter mixing, and stability of the water mass. The historical series of temperature distribution along the water column in the period 1984-1999, from which the holo-oligomictic character of Lake Orta emerges, is analysed. The monthly evaluation of the heat contents metre by metre from 0 to 143 m depth reveals how the complete winter mixing occurs only when the energy present within the whole column is less than 1,675 MJ m-2; above this value the circulation is only partial, as in the other deep subalpine lakes. A water layer in the deep hypolimnion has been shown to contain a climatic memory, which has generally increased since 1981. Walker’s stability analysis has revealed that when at a depth below 90 metres there is a level where 0.07 J m-2 are exceeded, total mixing cannot take place. In contrast, the Birgean work identifies, during the heating phase, the layers of the lake where energy is stored or lost.

  11. Effect of reducing portion size at a compulsory meal on later energy intake, gut hormones, and appetite in overweight adults.

    OpenAIRE

    Lewis, HB; Ahern, AL; Solis-Trapala, I; Walker, CG; Reimann, F; Gribble, FM; Jebb, SA

    2015-01-01

    OBJECTIVE: Larger portion sizes (PS) are associated with greater energy intake (EI), but little evidence exists on the appetitive effects of PS reduction. This study investigated the impact of reducing breakfast PS on subsequent EI, postprandial gastrointestinal hormone responses, and appetite ratings. METHODS: In a randomized crossover design (n = 33 adults; mean BMI 29 kg/m(2) ), a compulsory breakfast was based on 25% of gender-specific estimated daily energy requirements; PS was reduced b...

  12. Attitudes of South African oral hygienists towards compulsory community service.

    Science.gov (United States)

    Bhayat, A; Yengopal, V; Rudolph, M J; Naidoo, U; Vayej, A

    2008-02-01

    Compulsory Community Service (CCS) was introduced into the health service by the government to address the shortage and maldistribution of health professionals within the public sector. The aim of this study was to assess the perceptions of oral hygiene (OH) students, registered in 2004 at the five dental universities regarding the introduction of a 1-year-long CCS. To determine: (a) the students' socio-demographic profile and (b) their attitudes towards CCS. A self-administered questionnaire was hand delivered to all OH students who were registered during 2004 at the respective dental universities. The study yielded a response rate of 70% (109) with the average age of participants being 21.4 years. Most students were female (94%) and more than half were White (52%). More than half (53%) did not want to perform CCS even though 75% acknowledged its' importance. The most common concern for not supporting CCS was security (89%). Ninety per cent (90%) indicated that their preferred tasks would be to engage in clinical work and oral health promotion. Although the majority of participants supported the principles of CCS, a significant number were against the introduction citing security as their main concern. Most of the students preferred to perform clinical work and preventive programmes during their CCS.

  13. Mixing, Hydrography, and Flow in the eastern Channel of the Lucky Strike Segment

    OpenAIRE

    Tippenhauer, Sandra

    2015-01-01

    Diapycnal mixing in the deep ocean is known to be much stronger in the vicinity of rough topography of mid-ocean ridges than over abyssal plains. In this thesis a microstructure probe attached to an autonomous underwater vehicle (AUV) was used to infer the spatial distribution of the dissipation rate of turbulent kinetic energy in the central valley of the Mid-Atlantic Ridge. This represents the first successful realization of a horizontal, AUV-based, deep-ocean microstructure survey. The stu...

  14. Volume fracturing of deep shale gas horizontal wells

    Directory of Open Access Journals (Sweden)

    Tingxue Jiang

    2017-03-01

    Full Text Available Deep shale gas reservoirs buried underground with depth being more than 3500 m are characterized by high in-situ stress, large horizontal stress difference, complex distribution of bedding and natural cracks, and strong rock plasticity. Thus, during hydraulic fracturing, these reservoirs often reveal difficult fracture extension, low fracture complexity, low stimulated reservoir volume (SRV, low conductivity and fast decline, which hinder greatly the economic and effective development of deep shale gas. In this paper, a specific and feasible technique of volume fracturing of deep shale gas horizontal wells is presented. In addition to planar perforation, multi-scale fracturing, full-scale fracture filling, and control over extension of high-angle natural fractures, some supporting techniques are proposed, including multi-stage alternate injection (of acid fluid, slick water and gel and the mixed- and small-grained proppant to be injected with variable viscosity and displacement. These techniques help to increase the effective stimulated reservoir volume (ESRV for deep gas production. Some of the techniques have been successfully used in the fracturing of deep shale gas horizontal wells in Yongchuan, Weiyuan and southern Jiaoshiba blocks in the Sichuan Basin. As a result, Wells YY1HF and WY1HF yielded initially 14.1 × 104 m3/d and 17.5 × 104 m3/d after fracturing. The volume fracturing of deep shale gas horizontal well is meaningful in achieving the productivity of 50 × 108 m3 gas from the interval of 3500–4000 m in Phase II development of Fuling and also in commercial production of huge shale gas resources at a vertical depth of less than 6000 m.

  15. Deep Echo State Network (DeepESN): A Brief Survey

    OpenAIRE

    Gallicchio, Claudio; Micheli, Alessio

    2017-01-01

    The study of deep recurrent neural networks (RNNs) and, in particular, of deep Reservoir Computing (RC) is gaining an increasing research attention in the neural networks community. The recently introduced deep Echo State Network (deepESN) model opened the way to an extremely efficient approach for designing deep neural networks for temporal data. At the same time, the study of deepESNs allowed to shed light on the intrinsic properties of state dynamics developed by hierarchical compositions ...

  16. Ultra High Mode Mix in NIF NIC Implosions

    Science.gov (United States)

    Scott, Robbie; Garbett, Warren

    2017-10-01

    This work re-examines a sub-set of the low adiabat implosions from the National Ignition Campaign in an effort to better understand potential phenomenological sources of `excess' mix observed experimentally. An extensive effort has been made to match both shock-timing and backlit radiography (Con-A) implosion data in an effort to reproduce the experimental conditions as accurately as possible. Notably a 30% reduction in ablation pressure at peak drive is required to match the experimental data. The reduced ablation pressure required to match the experimental data allows the ablator to decompress, in turn causing the DT ice-ablator interface to go Rayleigh-Taylor unstable early in the implosion acceleration phase. Post-processing the runs with various mix models indicates high-mode mix from the DT ice-ablator interface may penetrate deep into the hotspot. This work offers a potential explanation of why these low-adiabat implosions exhibited significantly higher levels of mix than expected from high-fidelity multi-dimensional simulations. Through this new understanding, a possible route forward for low-adiabat implosions on NIF is suggested.

  17. Compulsory citizenship behavior and organizational citizenship behavior: the role of organizational identification and perceived interactional justice.

    Science.gov (United States)

    Zhao, Hongdan; Peng, Zhenglong; Chen, Hsiu-Kuei

    2014-01-01

    This article examines the psychological mechanism underlying the relationship between compulsory citizenship behavior (CCB) and organizational citizenship behavior (OCB) by developing a moderated mediation model. The model focuses on the mediating role of organizational identification and the moderating role of interactional justice in influencing the mediation. Using a time-lagged research design, the authors collected two waves of data from 388 supervisor-subordinate dyads in 67 teams to test the moderated mediation model. Results revealed that CCB negatively influenced OCB via impairing organizational identification. Moreover, interactional justice moderated the strength of the indirect effect of CCB on OCB (through organizational identification), such that the mediated relationship was stronger under low interactional justice than under high interactional justice.

  18. Spatial extent and dissipation of the deep chlorophyll layer in Lake Ontario during the Lake Ontario lower foodweb assessment, 2003 and 2008

    Science.gov (United States)

    Watkins, J. M.; Weidel, Brian M.; Rudstam, L. G.; Holek, K. T.

    2014-01-01

    Increasing water clarity in Lake Ontario has led to a vertical redistribution of phytoplankton and an increased importance of the deep chlorophyll layer in overall primary productivity. We used in situ fluorometer profiles collected in lakewide surveys of Lake Ontario in 2008 to assess the spatial extent and intensity of the deep chlorophyll layer. In situ fluorometer data were corrected with extracted chlorophyll data using paired samples from Lake Ontario collected in August 2008. The deep chlorophyll layer was present offshore during the stratified conditions of late July 2008 with maximum values from 4-13 μg l-1 corrected chlorophyll a at 10 to 17 m depth within the metalimnion. Deep chlorophyll layer was closely associated with the base of the thermocline and a subsurface maximum of dissolved oxygen, indicating the feature's importance as a growth and productivity maximum. Crucial to the deep chlorophyll layer formation, the photic zone extended deeper than the surface mixed layer in mid-summer. The layer extended through most of the offshore in July 2008, but was not present in the easternmost transect that had a deeper surface mixed layer. By early September 2008, the lakewide deep chlorophyll layer had dissipated. A similar formation and dissipation was observed in the lakewide survey of Lake Ontario in 2003.

  19. Effects of turbulence on mixed-phase deep convective clouds under different basic-state winds and aerosol concentrations

    Science.gov (United States)

    Lee, Hyunho; Baik, Jong-Jin; Han, Ji-Young

    2014-12-01

    The effects of turbulence-induced collision enhancement (TICE) on mixed-phase deep convective clouds are numerically investigated using a 2-D cloud model with bin microphysics for uniform and sheared basic-state wind profiles and different aerosol concentrations. Graupel particles account for the most of the cloud mass in all simulation cases. In the uniform basic-state wind cases, graupel particles with moderate sizes account for some of the total graupel mass in the cases with TICE, whereas graupel particles with large sizes account for almost all the total graupel mass in the cases without TICE. This is because the growth of ice crystals into small graupel particles is enhanced due to TICE. The changes in the size distributions of graupel particles due to TICE result in a decrease in the mass-averaged mean terminal velocity of graupel particles. Therefore, the downward flux of graupel mass, and thus the melting of graupel particles, is reduced due to TICE, leading to a decrease in the amount of surface precipitation. Moreover, under the low aerosol concentration, TICE increases the sublimation of ice particles, consequently playing a partial role in reducing the amount of surface precipitation. The effects of TICE are less pronounced in the sheared basic-state wind cases than in the uniform basic-state wind cases because the number of ice crystals is much smaller in the sheared basic-state wind cases than in the uniform basic-state wind cases. Thus, the size distributions of graupel particles in the cases with and without TICE show little difference.

  20. Women's stress in compulsory army service in Israel: A gendered perspective.

    Science.gov (United States)

    Huss, Ephrat; Cwikel, Julie

    2015-01-01

    A growing number of women are serving in the military in a variety of roles, yet information on their experience of stressors not associated with either combat or sexual harassment is not commonly reported. To present phenomenological data on stressors experienced in military service, together with the use of coping strategies as a way to focus on women's mental needs following deployment from service. Twenty women who had recently completed their compulsory army service in Israel drew a picture expressing stressors they experienced in the army. They analyzed their own pictures on three levels: the content, context, and the composition as expressing stress and the resources they used in coping with stress. Six themes were raised: proximity to war situations, coping with accidents in training soldiers under their command, a conflict between political values and military orders, witnessing the injury of another female soldier, responsibility for accidental injury of a civilian, and distress over the army placement. Coping resources were relational, primarily family and friend support, rather than from the army framework. This reliance on relational sources of support was both a resource and a source of vulnerability and is viewed as distinct from men's style of coping.

  1. Mixing on the Heard Island Plateau during HEOBI

    Science.gov (United States)

    Robertson, R.

    2016-12-01

    On the plateau near Heard and McDonald Islands, the water column was nearly always well mixed. Typically, temperature differences between the surface and the bottom, 100-200 m, were less than 0.2oC and often less that 0.1oC. Surface stratification developed through insolation and deep primarily through a combination of upwelling from canyons and over the edge of the plateau and tidal advection. This stratification was primarily removed by a combination of wind and tidal mixing. Persistent winds of 30 knots mixed the upper 20-50 m. Strong wind events, 40-60 knots, mixed the water column to 100-200 m depth, which over the plateau, was often the entire water column. Benthic tidal friction mixed the bottom 30-50 m. Although the water column was unstratified at the two plume sites intensively investigated, tidal velocities were baroclinic, probably due to topographic controls. Tidal advection changed the bottom temperatures by 0.5oC within 8 hours, more than doubling the prior stratification. Wind mixing quickly homogenized the water column, resulting in the surface often showing the deeper upwelling and advective events. Although acoustic plumes with bubbles were observed in the water column, there was no evidence of geothermal vents or geothermal influence on temperatures. Mixing by bubbles rising in the water column was indistinguishable from the wind and tidal mixing, although the strongest upward vertical velocities were observed at the sites of these acoustic/bubble plumes.

  2. The social surplus of broadband initiatives in compulsory education

    Directory of Open Access Journals (Sweden)

    David Peter Parsons

    2016-10-01

    Full Text Available In 2010, the New Zealand government embarked upon an ambitious programme of broadband infrastructure investment, a process that will continue until at least 2019. Part of this investment is specifically targeted at compulsory education, with initiatives that include bringing fibre connections to the school gate, supporting on-site network upgrades (including wireless and providing teaching, learning and support services delivered through these networks. Such investments are not made without some projections of the likely rate of return, but calculating return on investment (ROI in educational broadband is complex, as it encompasses a range of factors. This article reports on an interview-based study engaging a range of stakeholders in educational broadband provision. The study utilises a research model that considers the various elements of social surplus, namely; producer surplus (savings, producer surplus (profit and consumer surplus (perceived value over and above cost, to explore the elements of social surplus that have been used to define educational broadband ROI calculations and justify the scale of investment. The results indicate that all three components of social surplus are relevant, though the concept of profit can only be seen in the broader context of long term contributions to the economy. A note of caution is that projections of ROI based only on positive returns fail to acknowledge the potential for some innovations to actually increase costs. Further, purely quantitative models do not properly take into account qualitative components of consumer surplus.

  3. A Qualitative Strategy for the Balance of Compulsory Education in the County%县域义务教育均衡的质性策略探寻

    Institute of Scientific and Technical Information of China (English)

    孙玉红; 程媛; 赵丽

    2016-01-01

    县域义务教育均衡八项具体指标可以概括为教育场馆建设、教育装备配备、师资合理搭配三方面。义务教育均衡根本在于教育质量均衡，教师流动制度可以共享优质师资，学区连片共建能分享教育设施，远程在线培训能够推动教研改革，教育信息化可以互递网络资源，校本课程实践能够互补学校特色。县域义务教育实现优质均衡是基础教育的愿景。%County compulsory education balanced eight specific indicators can be summarized as three aspects of the con-struction of educational facilities, equipment, education and reasonable collocation of teachers. Compulsory education is fun-damental education quality equilibrium, teacher mobility system can share the quality of teachers, the school district to build a contiguous share of educational facilities, remote online training can promote the teaching reform, education information can pass cyber source, the practice of school-based curriculum can complement the school characteristics. County compulsory edu-cation to achieve high quality balance is the vision of basic education.

  4. Markov chains and mixing times

    CERN Document Server

    Levin, David A

    2017-01-01

    Markov Chains and Mixing Times is a magical book, managing to be both friendly and deep. It gently introduces probabilistic techniques so that an outsider can follow. At the same time, it is the first book covering the geometric theory of Markov chains and has much that will be new to experts. It is certainly THE book that I will use to teach from. I recommend it to all comers, an amazing achievement. -Persi Diaconis, Mary V. Sunseri Professor of Statistics and Mathematics, Stanford University Mixing times are an active research topic within many fields from statistical physics to the theory of algorithms, as well as having intrinsic interest within mathematical probability and exploiting discrete analogs of important geometry concepts. The first edition became an instant classic, being accessible to advanced undergraduates and yet bringing readers close to current research frontiers. This second edition adds chapters on monotone chains, the exclusion process and hitting time parameters. Having both exercises...

  5. Preventing compulsory admission to psychiatric inpatient care: Perceived coercion, empowerment and self-reported mental health functioning after 12 months of preventive monitoring

    OpenAIRE

    Barbara eLay; Barbara eLay; Thekla eDrack; Marco eBleiker; Silke eLengler; Christina eBlank; Wulf eRössler; Wulf eRössler; Wulf eRössler

    2015-01-01

    Objective: To evaluate effects of a preventive monitoring program targeted to reduce compulsory re-hospitalization and perceived coercion in patients with severe mental disorder. We analyze patient outcomes in terms of perceived coercion, empowerment and self-reported mental health functioning at 12 months. Methods: The program consists of individualized psycho-education, crisis cards and, after discharge from the psychiatric hospital, a 24-month preventive monitoring. In total, 238 psychiatr...

  6. Tree species effects on calcium cycling: The role of calcium uptake in deep soils

    NARCIS (Netherlands)

    Dijkstra, F.A.; Smits, M.M.

    2002-01-01

    Soil acidity and calcium (Ca) availability in the surface soil differ substantially beneath sugar maple (Acer saccharum) and eastern hemlock (Tsuga canadensis) trees in a mixed forest in northwestern Connecticut. We determined the effect of pumping of Ca from deep soil (rooting zone below 20-cm

  7. RPA spin-isospin nuclear response in the deep inelastic region

    International Nuclear Information System (INIS)

    Alberico, W.M.; Molinari, A.; De Pace, A.; Johnson, M.B.; Ericson, M.

    1985-11-01

    The spin-isospin volume responses of a finite nucleus are evaluated in the RPA frame, utilizing a harmonic oscillator basis. Particular emphasis is given to the mixing between the longitudinal and transverse couplings, which arise at the nuclear surface. We show that it reduces somewhat the contrast between the two spin responses. We compare the calculated transverse response with the experimental one extracted from deep inelastic electron scattering

  8. Why & When Deep Learning Works: Looking Inside Deep Learnings

    OpenAIRE

    Ronen, Ronny

    2017-01-01

    The Intel Collaborative Research Institute for Computational Intelligence (ICRI-CI) has been heavily supporting Machine Learning and Deep Learning research from its foundation in 2012. We have asked six leading ICRI-CI Deep Learning researchers to address the challenge of "Why & When Deep Learning works", with the goal of looking inside Deep Learning, providing insights on how deep networks function, and uncovering key observations on their expressiveness, limitations, and potential. The outp...

  9. Knowledge about the Greenhouse Effect and the Effects of the Ozone Layer among Norwegian Pupils Finishing Compulsory Education in 1989, 1993, and 2005--What Now?

    Science.gov (United States)

    Hansen, Pal J. Kirkeby

    2010-01-01

    The greenhouse effect and the effects of the ozone layer have been in the media and public focus for more than two decades. During the same period, Norwegian compulsory schools have had four national curricula. The two last-mentioned prescribe explicitly the two topics. Media and public discourse might have been sources of information causing…

  10. Dynamic stresses in a Francis model turbine at deep part load

    Science.gov (United States)

    Weber, Wilhelm; von Locquenghien, Florian; Conrad, Philipp; Koutnik, Jiri

    2017-04-01

    A comparison between numerically obtained dynamic stresses in a Francis model turbine at deep part load with experimental ones is presented. Due to the change in the electrical power mix to more content of new renewable energy sources, Francis turbines are forced to operate at deep part load in order to compensate stochastic nature of wind and solar power and to ensure grid stability. For the extension of the operating range towards deep part load improved understanding of the harsh flow conditions and their impact on material fatigue of hydraulic components is required in order to ensure long life time of the power unit. In this paper pressure loads on a model turbine runner from unsteady two-phase computational fluid dynamics simulation at deep part load are used for calculation of mechanical stresses by finite element analysis. Therewith, stress distribution over time is determined. Since only few runner rotations are simulated due to enormous numerical cost, more effort has to be spent to evaluation procedure in order to obtain objective results. By comparing the numerical results with measured strains accuracy of the whole simulation procedure is verified.

  11. Research on simulated infrared image utility evaluation using deep representation

    Science.gov (United States)

    Zhang, Ruiheng; Mu, Chengpo; Yang, Yu; Xu, Lixin

    2018-01-01

    Infrared (IR) image simulation is an important data source for various target recognition systems. However, whether simulated IR images could be used as training data for classifiers depends on the features of fidelity and authenticity of simulated IR images. For evaluation of IR image features, a deep-representation-based algorithm is proposed. Being different from conventional methods, which usually adopt a priori knowledge or manually designed feature, the proposed method can extract essential features and quantitatively evaluate the utility of simulated IR images. First, for data preparation, we employ our IR image simulation system to generate large amounts of IR images. Then, we present the evaluation model of simulated IR image, for which an end-to-end IR feature extraction and target detection model based on deep convolutional neural network is designed. At last, the experiments illustrate that our proposed method outperforms other verification algorithms in evaluating simulated IR images. Cross-validation, variable proportion mixed data validation, and simulation process contrast experiments are carried out to evaluate the utility and objectivity of the images generated by our simulation system. The optimum mixing ratio between simulated and real data is 0.2≤γ≤0.3, which is an effective data augmentation method for real IR images.

  12. What should we expect from Switzerland's compulsory dental insurance reform?

    Science.gov (United States)

    di Bella, Enrico; Krejci, Ivo; Ardu, Stefano; Leporatti, Lucia; Montefiori, Marcello

    2018-04-10

    A vast and heated debate is arising in Switzerland as a result of some recent citizens' initiatives aimed at introducing compulsory dental health care insurance. The Grand Conseils of the Vaud, Geneva, and Neuchâtel cantons recently approved three public initiatives and their citizens are expected to vote on the proposal in 2018. The process of collecting signatures has begun in several other cantons and the discussion has now moved to a national level. At present, there is no scientific research that can help policy-makers and citizens to understand the main economic implications of such reform. We attempt to fill this gap by analysing three critical issues: the level and determinants of unmet needs for dental care in Switzerland; the protection of vulnerable individuals; and the economic sustainability of reform. The results show that income is not a unique determinant of barriers to access to dental care but rather, cultural and socio-demographic factors impact the perceived level of unmet dental care needs. The reform might only partially, if at all, improve the equity of the current system. In addition, the results show that the 1% wage-based contribution that the reform promoters suggest should finance the insurance is inadequate to provide full and free dental care to Swiss residents, but is merely sufficient to guarantee basic preventive care, whereas this could be provided by dental hygienists for less.

  13. Pollen, water, and wind: Chaotic mixing in a puddle of water

    DEFF Research Database (Denmark)

    Jensen, Kaare Hartvig

    2016-01-01

    and nutrient distribution in puddles and small ponds.The flow patterns are generated by wind blowing across the puddle surface. This causes a shear stress at the atmospheric interface, which drives a flow in the liquid below. Chaotic mixing can occur if the wind direction changes over time. A fluid patch......This paper talks about how pine pollen grains dispersedin an approximately 1 m wide and 1 cm deep water puddle. The pollen has mixed due to wind blowing across the liquid surface, revealing a strikingly complex flow pattern. The flows revealed by nature’s tracer particles may influence circulation...

  14. The Deep Atmospheric Boundary Layer and Its Significance to the Stratosphere and Troposphere Exchange over the Tibetan Plateau

    Science.gov (United States)

    Chen, Xuelong; Añel, Juan A.; Su, Zhongbo; de la Torre, Laura; Kelder, Hennie; van Peet, Jacob; Ma, Yaoming

    2013-01-01

    In this study the depth of the atmospheric boundary layer (ABL) over the Tibetan Plateau was measured during a regional radiosonde observation campaign in 2008 and found to be deeper than indicated by previously measurements. Results indicate that during fair weather conditions on winter days, the top of the mixed layers can be up to 5 km above the ground (9.4 km above sea level). Measurements also show that the depth of the ABL is quite distinct for three different periods (winter, monsoon-onset, and monsoon seasons). Turbulence at the top of a deep mixing layer can rise up to the upper troposphere. As a consequence, as confirmed by trajectory analysis, interaction occurs between deep ABLs and the low tropopause during winter over the Tibetan Plateau. PMID:23451108

  15. Modification of the deep salinity-maximum in the Southern Ocean by circulation in the Antarctic Circumpolar Current and the Weddell Gyre

    Science.gov (United States)

    Donnelly, Matthew; Leach, Harry; Strass, Volker

    2017-07-01

    The evolution of the deep salinity-maximum associated with the Lower Circumpolar Deep Water (LCDW) is assessed using a set of 37 hydrographic sections collected over a 20-year period in the Southern Ocean as part of the WOCE/CLIVAR programme. A circumpolar decrease in the value of the salinity-maximum is observed eastwards from the North Atlantic Deep Water (NADW) in the Atlantic sector of the Southern Ocean through the Indian and Pacific sectors to Drake Passage. Isopycnal mixing processes are limited by circumpolar fronts, and in the Atlantic sector, this acts to limit the direct poleward propagation of the salinity signal. Limited entrainment occurs into the Weddell Gyre, with LCDW entering primarily through the eddy-dominated eastern limb. A vertical mixing coefficient, κV of (2.86 ± 1.06) × 10-4 m2 s-1 and an isopycnal mixing coefficient, κI of (8.97 ± 1.67) × 102 m2 s-1 are calculated for the eastern Indian and Pacific sectors of the Antarctic Circumpolar Current (ACC). A κV of (2.39 ± 2.83) × 10-5 m2 s-1, an order of magnitude smaller, and a κI of (2.47 ± 0.63) × 102 m2 s-1, three times smaller, are calculated for the southern and eastern Weddell Gyre reflecting a more turbulent regime in the ACC and a less turbulent regime in the Weddell Gyre. In agreement with other studies, we conclude that the ACC acts as a barrier to direct meridional transport and mixing in the Atlantic sector evidenced by the eastward propagation of the deep salinity-maximum signal, insulating the Weddell Gyre from short-term changes in NADW characteristics.

  16. Enhanced Deep Blue Aerosol Retrieval Algorithm: The Second Generation

    Science.gov (United States)

    Hsu, N. C.; Jeong, M.-J.; Bettenhausen, C.; Sayer, A. M.; Hansell, R.; Seftor, C. S.; Huang, J.; Tsay, S.-C.

    2013-01-01

    The aerosol products retrieved using the MODIS collection 5.1 Deep Blue algorithm have provided useful information about aerosol properties over bright-reflecting land surfaces, such as desert, semi-arid, and urban regions. However, many components of the C5.1 retrieval algorithm needed to be improved; for example, the use of a static surface database to estimate surface reflectances. This is particularly important over regions of mixed vegetated and non- vegetated surfaces, which may undergo strong seasonal changes in land cover. In order to address this issue, we develop a hybrid approach, which takes advantage of the combination of pre-calculated surface reflectance database and normalized difference vegetation index in determining the surface reflectance for aerosol retrievals. As a result, the spatial coverage of aerosol data generated by the enhanced Deep Blue algorithm has been extended from the arid and semi-arid regions to the entire land areas.

  17. Study on the mechanisms making the deep groundwater quality. Part 3

    Energy Technology Data Exchange (ETDEWEB)

    Ohara, Kin-ichi [CHISHITSU-KISO-KOGYO Co., Ltd. (Japan)

    1997-03-01

    We compiled geological data and chemical data of deep groundwater in the Joban Coal Field, and examined the qualities and the changes of groundwater by geochemical analysis and numerical simulation. On the chemical analysis, we classified the chemical type of the water which gathered in the coal mine tunnels, and clarified their distributions. Moreover we analyzed isotopes in the water which picked up from wells under running. As a consequence of these analysis, the origin of the groundwater character in the Joban Coal Field is inferred to be mostly mixed water with present sea water and fresh water. We detected some groundwater were mixed with fresh water in some ten years, while we recognized that some groundwater which were mixed clearly with fossilized sea water also exist. Concerning the numerical simulation, we set up the 3 dimensional model in this field which roughly represents the geological structures and physical conditions, and collected the data to inspect the analytical results. We simulated hydraulic conditions of this model for 100 years including three phases; those are the model with no tunnels, the model at mining, and abandoned mine model with re-submergence. In consequence, volume of influx water to the tunnels and restoration of water level after re-submergence are nearly represented, and we recognized the availability of this large-scale analysis. Moreover, we tried to simulate the very large 2 dimensional water system including the boundary of fresh water and sea water, and analyzed very long time change of the deep groundwater which was caused by sea level change. (author). 63 refs.

  18. Lunar nitrogen: Secular variation or mixing?

    International Nuclear Information System (INIS)

    Norris, S.J.; Wright, I.P.; Pillinger, C.T.

    1986-01-01

    The two current models to explain the nearly 40% variation of the lunar nitrogen isotopic composition are: (1) secular variation of solar wind nitrogen; and (2) a two component mixing model having a constant, heavy solar wind admixed with varying amounts of indigenous light lunar N (LLN). Both models are needed to explain the step pyrolysis extraction profile. The secular variation model proposes that the low temperature release is modern day solar wind implanted into grain surfaces, the 900 C to 1100 C release is from grain surfaces which were once exposed to the ancient solar wind but which are now trapped inside agglutinates, and the >1100 C release as spallogenic N produced by cosmic rays. The mixing model ascribes the components to solar wind, indigenous lunar N and spallogenic N respectively. An extension of either interpretation is that the light N seen in lunar breccias or deep drill cores represent conditions when more N-14 was available to the lunar surface

  19. Advanced Solid State Lighting for AES Deep Space Hab Project

    Science.gov (United States)

    Holbert, Eirik

    2015-01-01

    The advanced Solid State Lighting (SSL) assemblies augmented 2nd generation modules under development for the Advanced Exploration Systems Deep Space Habitat in using color therapy to synchronize crew circadian rhythms. Current RGB LED technology does not produce sufficient brightness to adequately address general lighting in addition to color therapy. The intent is to address both through a mix of white and RGB LEDs designing for fully addressable alertness/relaxation levels as well as more dramatic circadian shifts.

  20. Natural deep eutectic solvents as new potential media for green technology

    International Nuclear Information System (INIS)

    Dai, Yuntao; Spronsen, Jaap van; Witkamp, Geert-Jan; Verpoorte, Robert; Choi, Young Hae

    2013-01-01

    Highlights: ► Natural products were used as a source for deep eutectic solvents and ionic liquids. ► We define own chemical and physical properties of natural deep eutectic solvents. ► Interaction between natural deep eutectic solvents and solutes was confirmed by NMR. ► The developed natural deep eutectic solvents were applied as green media. - Abstract: Developing new green solvents is one of the key subjects in Green Chemistry. Ionic liquids (ILs) and deep eutectic solvents, thus, have been paid great attention to replace current harsh organic solvents and have been applied to many chemical processing such as extraction and synthesis. However, current ionic liquids and deep eutectic solvents have still limitations to be applied to a real chemical industry due to toxicity against human and environment and high cost of ILs and solid state of most deep eutectic solvents at room temperature. Recently we discovered that many plant abundant primary metabolites changed their state from solid to liquid when they were mixed in proper ratio. This finding made us hypothesize that natural deep eutectic solvents (NADES) play a role as alternative media to water in living organisms and tested a wide range of natural products, which resulted in discovery of over 100 NADES from nature. In order to prove deep eutectic feature the interaction between the molecules was investigated by nuclear magnetic resonance spectroscopy. All the tested NADES show clear hydrogen bonding between components. As next step physical properties of NADES such as water activity, density, viscosity, polarity and thermal properties were measured as well as the effect of water on the physical properties. In the last stage the novel NADES were applied to the solubilization of wide range of biomolecules such as non-water soluble bioactive natural products, gluten, starch, and DNA. In most cases the solubility of the biomolecules evaluated in this study was greatly higher than water. Based on the

  1. Natural deep eutectic solvents as new potential media for green technology

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Yuntao [Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA Leiden (Netherlands); Spronsen, Jaap van; Witkamp, Geert-Jan [Laboratory for Process Equipment, Delft University of Technology, Delft (Netherlands); Verpoorte, Robert [Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA Leiden (Netherlands); Choi, Young Hae, E-mail: y.choi@chem.leidenuniv.nl [Natural Products Laboratory, Institute of Biology, Leiden University, 2300 RA Leiden (Netherlands)

    2013-03-05

    Highlights: ► Natural products were used as a source for deep eutectic solvents and ionic liquids. ► We define own chemical and physical properties of natural deep eutectic solvents. ► Interaction between natural deep eutectic solvents and solutes was confirmed by NMR. ► The developed natural deep eutectic solvents were applied as green media. - Abstract: Developing new green solvents is one of the key subjects in Green Chemistry. Ionic liquids (ILs) and deep eutectic solvents, thus, have been paid great attention to replace current harsh organic solvents and have been applied to many chemical processing such as extraction and synthesis. However, current ionic liquids and deep eutectic solvents have still limitations to be applied to a real chemical industry due to toxicity against human and environment and high cost of ILs and solid state of most deep eutectic solvents at room temperature. Recently we discovered that many plant abundant primary metabolites changed their state from solid to liquid when they were mixed in proper ratio. This finding made us hypothesize that natural deep eutectic solvents (NADES) play a role as alternative media to water in living organisms and tested a wide range of natural products, which resulted in discovery of over 100 NADES from nature. In order to prove deep eutectic feature the interaction between the molecules was investigated by nuclear magnetic resonance spectroscopy. All the tested NADES show clear hydrogen bonding between components. As next step physical properties of NADES such as water activity, density, viscosity, polarity and thermal properties were measured as well as the effect of water on the physical properties. In the last stage the novel NADES were applied to the solubilization of wide range of biomolecules such as non-water soluble bioactive natural products, gluten, starch, and DNA. In most cases the solubility of the biomolecules evaluated in this study was greatly higher than water. Based on the

  2. Deep iCrawl: An Intelligent Vision-Based Deep Web Crawler

    OpenAIRE

    R.Anita; V.Ganga Bharani; N.Nityanandam; Pradeep Kumar Sahoo

    2011-01-01

    The explosive growth of World Wide Web has posed a challenging problem in extracting relevant data. Traditional web crawlers focus only on the surface web while the deep web keeps expanding behind the scene. Deep web pages are created dynamically as a result of queries posed to specific web databases. The structure of the deep web pages makes it impossible for traditional web crawlers to access deep web contents. This paper, Deep iCrawl, gives a novel and vision-based app...

  3. Spiraling pathways of global deep waters to the surface of the Southern Ocean.

    Science.gov (United States)

    Tamsitt, Veronica; Drake, Henri F; Morrison, Adele K; Talley, Lynne D; Dufour, Carolina O; Gray, Alison R; Griffies, Stephen M; Mazloff, Matthew R; Sarmiento, Jorge L; Wang, Jinbo; Weijer, Wilbert

    2017-08-02

    Upwelling of global deep waters to the sea surface in the Southern Ocean closes the global overturning circulation and is fundamentally important for oceanic uptake of carbon and heat, nutrient resupply for sustaining oceanic biological production, and the melt rate of ice shelves. However, the exact pathways and role of topography in Southern Ocean upwelling remain largely unknown. Here we show detailed upwelling pathways in three dimensions, using hydrographic observations and particle tracking in high-resolution models. The analysis reveals that the northern-sourced deep waters enter the Antarctic Circumpolar Current via southward flow along the boundaries of the three ocean basins, before spiraling southeastward and upward through the Antarctic Circumpolar Current. Upwelling is greatly enhanced at five major topographic features, associated with vigorous mesoscale eddy activity. Deep water reaches the upper ocean predominantly south of the Antarctic Circumpolar Current, with a spatially nonuniform distribution. The timescale for half of the deep water to upwell from 30° S to the mixed layer is ~60-90 years.Deep waters of the Atlantic, Pacific and Indian Oceans upwell in the Southern Oceanbut the exact pathways are not fully characterized. Here the authors present a three dimensional view showing a spiralling southward path, with enhanced upwelling by eddy-transport at topographic hotspots.

  4. Deposits of minerals of the Kirovograd ore region of the Ukrainian shield: connection with the deep process

    OpenAIRE

    Usenko, O.V.

    2017-01-01

    Conditions of magmatic rocks complexes and mineral deposits formation of the central part of the Ingul block are determined by existence of two melting sources in the mantle and the crust as well as by the deep permeable «transform» zone - tectonic suture Kherson-Smolensk. Along the deep transform zone supply of the mantle source by melts and fluids is realized and the existence of the crust source provides mixing of earlier melts with new portions added from the mantle. Changing of compositi...

  5. Pathways of upwelling deep waters to the surface of the Southern Ocean

    Science.gov (United States)

    Tamsitt, Veronica; Drake, Henri; Morrison, Adele; Talley, Lynne; Dufour, Carolina; Gray, Alison; Griffies, Stephen; Mazloff, Matthew; Sarmiento, Jorge; Wang, Jinbo; Weijer, Wilbert

    2017-04-01

    Upwelling of Atlantic, Indian and Pacific deep waters to the sea surface in the Southern Ocean closes the global overturning circulation and is fundamentally important for oceanic uptake of anthropogenic carbon and heat, nutrient resupply for sustaining oceanic biological production, and the melt rate of ice shelves. Here we go beyond the two-dimensional view of Southern Ocean upwelling, to show detailed Southern Ocean upwelling pathways in three dimensions, using hydrographic observations and particle tracking in high-resolution ocean and climate models. The northern deep waters enter the Antarctic Circumpolar Current (ACC) via narrow southward currents along the boundaries of the three ocean basins, before spiraling southeastward and upward through the ACC. Upwelling is greatly enhanced at five major topographic features, associated with vigorous mesoscale eddy activity. Deep water reaches the upper ocean predominantly south of the southern ACC boundary, with a spatially nonuniform distribution, regionalizing warm water supply to Antarctic ice shelves and the delivery of nutrient and carbon-rich water to the sea surface. The timescale for half of the deep water to upwell from 30°S to the mixed layer is on the order of 60-90 years, which has important implications for the timescale for signals to propagate through the deep ocean. In addition, we quantify the diabatic transformation along particle trajectories, to identify where diabatic processes are important along the upwelling pathways.

  6. Effects of a Deep Mixed Shell on Solar g-Modes, p-Modes, and Neutrino Flux

    Science.gov (United States)

    Wolff, Charles L.

    2009-08-01

    A mixed-shell model that reflects g-modes away from the Sun's center is developed further by calibrating its parameters and evaluating a mixing mechanism: buoyancy. The shell roughly doubles g-mode oscillation periods and would explain why there is no definitive detection of their periods. But the shell has only minor effects on most p-modes. The model provides a mechanism for causing short-term fluctuations in neutrino flux and makes plausible the correlations between this flux and solar activity levels. Relations are derived for a shell heated asymmetrically by transient increases in nuclear burning in small "hot spots." The size of these spots and the timing of a heating event are governed by sets(ell) of standing asymptotic g-modes, coupled by a maximal principle that greatly enhances their excitation and concentrates power toward the equator, assisting the detection of higher-ell sets. Signals from all sets, except one, in the range 2 energy to mix the corresponding shell in a standard solar model in Lt107 yr.

  7. 信息技术推进义务教育均衡发展的思考%Reflection on the Information Technique to Promote Balanced Development of Compulsory Education

    Institute of Scientific and Technical Information of China (English)

    夏云峰

    2015-01-01

    Information technology development to break the people learn, the space constraints. For people to learn, work, and life offers a convenient platform. The development and application of information technology will bring a revolution in education. Infor-mation technology-based support, could be more effective solution to the balanced development of compulsory education and pro-mote balanced development of compulsory education .%信息技术的发展打破了人们学习受时间、空间的限制.为人们的学习、工作、生活提供了一个便利的平台.信息技术的发展和应用将带来教育的革命.基于信息技术的支持之下,可以更加有效的解决义务教育均衡发展问题,促进义务教育均衡发展.

  8. Gender differences in prevalence and correlates of antisocial personality disorder among heroin dependent users in compulsory isolation treatment in China.

    Science.gov (United States)

    Yang, Mei; Mamy, Jules; Zhou, Liang; Liao, Yan-Hui; Wang, Qiang; Seewoobudul, Vasish; Xiao, Shui-Yuan; Hao, Wei

    2014-03-01

    Little is known about gender difference in correlates of antisocial personality disorder (ASPD) among drug users. To detect gender difference in correlates of ASPD in a Chinese heroin dependent sample. Structured interviews were conducted among 882 heroin dependent users in two compulsory isolation settings in Changsha, China. Descriptive statistics were employed to report sample characteristics by gender. Bivariate relationships were examined between co-occurring ASPD and variables measuring demographic, drug use, and psychiatric co-morbidities. Multivariate logistic regressions with stepwise forward method were conducted to determine independent predictors for co-occurring ASPD. All analyses examining correlates of co-occurring ASPD were conducted for the total, the male and the female participants respectively to detect both the common and the unique correlates of ASPD by gender. Of the total participants, 41.4% (54.2% of males and 15.4% of females) met the DSM-IV criteria of ASPD. For male participants, lower educational level, unemployment, unmarried, younger age at first heroin use, previous history of compulsory treatment, larger amounts of heroin used per day and poly-drug abuse during past month before admission, as well as psychiatric co-morbidities of lifetime major depressive disorder and borderline personality disorder were independent predictors for co-occurring ASPD; while for female participants, only three variables: younger age at first heroin use, paranoid personality disorder and borderline personality disorder were independent predictors for co-occurring ASPD. Gender differences in prevalence and correlates of ASPD among heroin dependent users were detected. The findings highlight a need for gender-specific interventions. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Numerical assessment of the origin of deep salinity in a low permeability fractured medium

    International Nuclear Information System (INIS)

    Guimera, Jordi; Ruiz, Eduardo; Luna, Miguel; Arcos, David; Domenech, Cristina; Jordana, Salvador; Saegusa, Hiromitsu; Iwatsuki, Teruki

    2007-01-01

    Many possible origins have been proposed for the saline groundwater observed in many deep geological environments. In particular, samples obtained from deep boreholes located in granite at the Mizunami Underground Research Laboratory in Central Japan show total dissolved solids increasing to 50 mmol/L at depths below 800 m. Different hypothesis have been formulated to explain the observed fluid composition, among them, long-term water-rock interaction, mixing with residual fluids of magmatic origin and relict seawater dating from Miocene times. A review of the hydrochemical and isotopic data suggests that the three above hypotheses may be valid, at least to different degrees, or that processes acting over more recent geological times may be involved. The origin of the salinity was assessed by simulating land emersion by means of changing the upper recharge boundary. In this manner the Miocene seawater was modeled as being continually mixed with fresh water until the present time. The effects of different retardation processes were considered by varying factors such as matrix diffusion and fracture conductivity. Finally, geochemical reactions reproduced trends in major ions and master variables. This study shows that the salinity observed in the boreholes can be explained qualitatively as residual Miocene age seawater subjected to alteration due to long-term contact with the host material and continuous mixing with meteoric groundwater. (authors)

  10. How stratospheric are deep stratospheric intrusions? LUAMI 2008

    Directory of Open Access Journals (Sweden)

    T. Trickl

    2016-07-01

    Full Text Available A large-scale comparison of water-vapour vertical-sounding instruments took place over central Europe on 17 October 2008, during a rather homogeneous deep stratospheric intrusion event (LUAMI, Lindenberg Upper-Air Methods Intercomparison. The measurements were carried out at four observational sites: Payerne (Switzerland, Bilthoven (the Netherlands, Lindenberg (north-eastern Germany, and the Zugspitze mountain (Garmisch-Partenkichen, German Alps, and by an airborne water-vapour lidar system creating a transect of humidity profiles between all four stations. A high data quality was verified that strongly underlines the scientific findings. The intrusion layer was very dry with a minimum mixing ratios of 0 to 35 ppm on its lower west side, but did not drop below 120 ppm on the higher-lying east side (Lindenberg. The dryness hardens the findings of a preceding study (“Part 1”, Trickl et al., 2014 that, e.g., 73 % of deep intrusions reaching the German Alps and travelling 6 days or less exhibit minimum mixing ratios of 50 ppm and less. These low values reflect values found in the lowermost stratosphere and indicate very slow mixing with tropospheric air during the downward transport to the lower troposphere. The peak ozone values were around 70 ppb, confirming the idea that intrusion layers depart from the lowermost edge of the stratosphere. The data suggest an increase of ozone from the lower to the higher edge of the intrusion layer. This behaviour is also confirmed by stratospheric aerosol caught in the layer. Both observations are in agreement with the idea that sections of the vertical distributions of these constituents in the source region were transferred to central Europe without major change. LAGRANTO trajectory calculations demonstrated a rather shallow outflow from the stratosphere just above the dynamical tropopause, for the first time confirming the conclusions in “Part 1” from the Zugspitze CO observations. The

  11. Parameterization of Mixed Layer and Deep-Ocean Mesoscales Including Nonlinearity

    Science.gov (United States)

    Canuto, V. M.; Cheng, Y.; Dubovikov, M. S.; Howard, A. M.; Leboissetier, A.

    2018-01-01

    In 2011, Chelton et al. carried out a comprehensive census of mesoscales using altimetry data and reached the following conclusions: "essentially all of the observed mesoscale features are nonlinear" and "mesoscales do not move with the mean velocity but with their own drift velocity," which is "the most germane of all the nonlinear metrics."� Accounting for these results in a mesoscale parameterization presents conceptual and practical challenges since linear analysis is no longer usable and one needs a model of nonlinearity. A mesoscale parameterization is presented that has the following features: 1) it is based on the solutions of the nonlinear mesoscale dynamical equations, 2) it describes arbitrary tracers, 3) it includes adiabatic (A) and diabatic (D) regimes, 4) the eddy-induced velocity is the sum of a Gent and McWilliams (GM) term plus a new term representing the difference between drift and mean velocities, 5) the new term lowers the transfer of mean potential energy to mesoscales, 6) the isopycnal slopes are not as flat as in the GM case, 7) deep-ocean stratification is enhanced compared to previous parameterizations where being more weakly stratified allowed a large heat uptake that is not observed, 8) the strength of the Deacon cell is reduced. The numerical results are from a stand-alone ocean code with Coordinated Ocean-Ice Reference Experiment I (CORE-I) normal-year forcing.

  12. Microbial ecology of deep-sea hypersaline anoxic basins

    KAUST Repository

    Merlino, Giuseppe

    2018-05-09

    Deep hypersaline anoxic basins (DHABs) are unique water bodies occurring within fractures at the bottom of the sea, where the dissolution of anciently buried evaporites created dense anoxic brines that are separated by a chemocline/pycnocline from the overlying oxygenated deep-seawater column. DHABs have been described in the Gulf of Mexico, the Mediterranean Sea, the Black Sea and the Red Sea. They are characterized by prolonged historical separation of the brines from the upper water column due to lack of mixing and by extreme conditions of salinity, anoxia, and relatively high hydrostatic pressure and temperatures. Due to these combined selection factors, unique microbial assemblages thrive in these polyextreme ecosystems. The topological localization of the different taxa in the brine-seawater transition zone coupled with the metabolic interactions and niche adaptations determine the metabolic functioning and biogeochemistry of DHABs. In particular, inherent metabolic strategies accompanied by genetic adaptations have provided insights on how prokaryotic communities can adapt to salt-saturated condition. Here, we review the current knowledge on the diversity, genomics, metabolisms and ecology of prokaryotes in DHABs.

  13. Rising to the human rights challenge in compulsory treatment--new approaches to mental health law in Australia.

    Science.gov (United States)

    Callaghan, Sascha; Ryan, Christopher J

    2012-07-01

    To analyse, and explain to Australasian psychiatrists, recent proposed changes to the terms of coercive treatment for mental illness in Tasmania and Victoria and to place the proposals in the context of a broader human rights framework that is likely to impact the future shape of mental health legislation more generally. The Australian law reform proposals are reviewed against the requirements of numerous human rights instruments, including the recently ratified United Nations Convention on the Rights of Persons with Disabilities. Ethical and legal arguments are made to support the proposed changes and to introduce others, taking into account academic commentary on mental health law and recent empirical work on the ability to usefully categorise patients by their likelihood of harm to self and others. The Victorian and Tasmanian draft mental health bills propose a new basis for compulsory psychiatric treatment in Australasia. If they become law, coercive psychiatric treatment could only be applied to patients who lack decision-making capacity. The Tasmanian draft bill also sets a new benchmark for timely independent review of compulsory treatment. However both jurisdictions propose to retain an 'additional harm' test which must be satisfied before patients may be treated without consent. This differs from non-psychiatric cases, where if patients are unable to consent to medical treatment for themselves, they will be entitled to receive coercive treatment if it is in their best interests. The proposed changes under the Tasmanian and Victorian draft mental health bills will ensure that, in line with local and international human rights obligations, only patients who lack decision-making capacity may be coercively treated for mental illness. However the continuing 'additional harm' criteria may breach human rights obligations by imposing a discriminatory threshold for care on patients who are unable to consent to treatment for themselves. This could be avoided by

  14. Deep learning

    CERN Document Server

    Goodfellow, Ian; Courville, Aaron

    2016-01-01

    Deep learning is a form of machine learning that enables computers to learn from experience and understand the world in terms of a hierarchy of concepts. Because the computer gathers knowledge from experience, there is no need for a human computer operator to formally specify all the knowledge that the computer needs. The hierarchy of concepts allows the computer to learn complicated concepts by building them out of simpler ones; a graph of these hierarchies would be many layers deep. This book introduces a broad range of topics in deep learning. The text offers mathematical and conceptual background, covering relevant concepts in linear algebra, probability theory and information theory, numerical computation, and machine learning. It describes deep learning techniques used by practitioners in industry, including deep feedforward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology; and it surveys such applications as natural language proces...

  15. Projection decomposition algorithm for dual-energy computed tomography via deep neural network.

    Science.gov (United States)

    Xu, Yifu; Yan, Bin; Chen, Jian; Zeng, Lei; Li, Lei

    2018-03-15

    Dual-energy computed tomography (DECT) has been widely used to improve identification of substances from different spectral information. Decomposition of the mixed test samples into two materials relies on a well-calibrated material decomposition function. This work aims to establish and validate a data-driven algorithm for estimation of the decomposition function. A deep neural network (DNN) consisting of two sub-nets is proposed to solve the projection decomposition problem. The compressing sub-net, substantially a stack auto-encoder (SAE), learns a compact representation of energy spectrum. The decomposing sub-net with a two-layer structure fits the nonlinear transform between energy projection and basic material thickness. The proposed DNN not only delivers image with lower standard deviation and higher quality in both simulated and real data, and also yields the best performance in cases mixed with photon noise. Moreover, DNN costs only 0.4 s to generate a decomposition solution of 360 × 512 size scale, which is about 200 times faster than the competing algorithms. The DNN model is applicable to the decomposition tasks with different dual energies. Experimental results demonstrated the strong function fitting ability of DNN. Thus, the Deep learning paradigm provides a promising approach to solve the nonlinear problem in DECT.

  16. Deep-level optical spectroscopy investigation of N-doped TiO2 films

    International Nuclear Information System (INIS)

    Nakano, Yoshitaka; Morikawa, Takeshi; Ohwaki, Takeshi; Taga, Yasunori

    2005-01-01

    N-doped TiO 2 films were deposited on n + -GaN/Al 2 O 3 substrates by reactive magnetron sputtering and subsequently crystallized by annealing at 550 deg. C in flowing N 2 gas. The N-doping concentration was ∼8.8%, as determined from x-ray photoelectron spectroscopy measurements. Deep-level optical spectroscopy measurements revealed two characteristic deep levels located at ∼1.18 and ∼2.48 eV below the conduction band. The 1.18 eV level is probably attributable to the O vacancy state and can be active as an efficient generation-recombination center. Additionally, the 2.48 eV band is newly introduced by the N doping and contributes to band-gap narrowing by mixing with the O 2p valence band

  17. A Survey of Psychological, Motivational, Family and Perceptions of Physics Education Factors that Explain 15-Year-Old Students' Aspirations to Study Physics in Post-Compulsory English Schools

    Science.gov (United States)

    Mujtaba, Tamjid; Reiss, Michael J.

    2014-01-01

    This paper investigates the factors that influence 15-year-old students' intentions to study physics post-16, when it is no longer compulsory. The analysis is based on the year 10 (age, 15 years) responses of 5,034 students from 137 England schools as learners of physics during the academic year 2008-2009. Factor analyses uncovered a range of…

  18. An environmental model study of the deep layers of the North East Atlantic

    International Nuclear Information System (INIS)

    Bork, I.

    1989-01-01

    The field work of the north Atlantic monitoring Program (NOAMP) was supplemented by numerical simulations of the transport of radionuclides in the North Atlantic Ocean by annual mean flows and mixing processes. During the last year of NOAMP, a different attempt was made to compute the current field and three-dimensional trajectories of particles released in deep layers of the NOAMP area. It is the subject of this paper. The model used is of Bryan/Semtner type, but with smoothed topography and climatological (winter) temperature and salinity data. The results form a compromise between interpretation of climatological temperature and salinity data and the complete prediction of the current field by prognostic calculations, which yields a deep flow pattern that agrees with some ideas of the abyssal circulation

  19. Are recent graduates enough prepared to perform obstetric skills in their rural and compulsory year? A study from Ecuador.

    Science.gov (United States)

    Sánchez Del Hierro, Galo; Remmen, Roy; Verhoeven, Veronique; Van Royen, Paul; Hendrickx, Kristin

    2014-07-31

    The aim of this study was to assess the possible mismatch of obstetrical skills between the training offered in Ecuadorian medical schools and the tasks required for compulsory rural service. Primary care, rural health centres in Southern Ecuador. A total of 92 recent graduated medical doctors during their compulsory rural year. A web-based survey was developed with 21 obstetrical skills. The questionnaire was sent to all rural doctors who work in Loja province, Southern Ecuador, at the Ministry of Health (n=92). 'importance of skills in rural practice' with a five-point Likert-type scale (1= strongly disagree; 5= strongly agree); and 'clerkship experience' using a nominal scale divided in five levels: level 1 (not seen, not performed) to level 5 (performed 10 times or more). Spearman's rank correlation coefficient (r) was used to observe associations. A negative correlation was found in the skills: 'episiotomy and repair', 'umbilical vein catheterisation', 'speculum examination', 'evaluation of cervical dilation during active labour', 'neonatal resuscitation' and 'vacuum-assisted vaginal delivery'. For instance 'Episiotomy and repair' is important (strongly agree and agree) to 100% of respondents, but in practice, only 38.9% of rural doctors performed the task three times and 8.3% only once during the internship, similar pattern is seen in the others. In this study we have noted the gap between the medical needs of populations in rural areas and training provided during the clerkship experiences of physicians during their rural service year. It is imperative to ensure that rural doctors are appropriately trained and skilled in the performance of routine obstetrical duties. This will help to decrease perinatal morbidity and mortality in rural Ecuador. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  20. Are recent graduates enough prepared to perform obstetric skills in their rural and compulsory year? A study from Ecuador

    Science.gov (United States)

    Sánchez del Hierro, Galo; Remmen, Roy; Verhoeven, Veronique; Van Royen, Paul; Hendrickx, Kristin

    2014-01-01

    Objectives The aim of this study was to assess the possible mismatch of obstetrical skills between the training offered in Ecuadorian medical schools and the tasks required for compulsory rural service. Setting Primary care, rural health centres in Southern Ecuador. Participants A total of 92 recent graduated medical doctors during their compulsory rural year. Primary and secondary outcomes measures A web-based survey was developed with 21 obstetrical skills. The questionnaire was sent to all rural doctors who work in Loja province, Southern Ecuador, at the Ministry of Health (n=92). We measured two categories ‘importance of skills in rural practice’ with a five-point Likert-type scale (1= strongly disagree; 5= strongly agree); and ‘clerkship experience’ using a nominal scale divided in five levels: level 1 (not seen, not performed) to level 5 (performed 10 times or more). Spearman's rank correlation coefficient (r) was used to observe associations. Results A negative correlation was found in the skills: ‘episiotomy and repair’, ‘umbilical vein catheterisation’, ‘speculum examination’, ‘evaluation of cervical dilation during active labour’, ‘neonatal resuscitation’ and ‘vacuum-assisted vaginal delivery’. For instance ‘Episiotomy and repair’ is important (strongly agree and agree) to 100% of respondents, but in practice, only 38.9% of rural doctors performed the task three times and 8.3% only once during the internship, similar pattern is seen in the others. Conclusions In this study we have noted the gap between the medical needs of populations in rural areas and training provided during the clerkship experiences of physicians during their rural service year. It is imperative to ensure that rural doctors are appropriately trained and skilled in the performance of routine obstetrical duties. This will help to decrease perinatal morbidity and mortality in rural Ecuador. PMID:25082424

  1. Mobile phone voting for participation and engagement in a large compulsory law course

    Directory of Open Access Journals (Sweden)

    Chad Habel

    2014-04-01

    Full Text Available This article reports on an action-research project designed to investigate the effect of a technological intervention on the complex interactions between student engagement, participation, attendance and preparation in a large lecture delivered as part of a compulsory first-year law course, a discipline which has not been the focus of any previous study. The technology used was VotApedia, a form of mobile phone voting, and it was implemented in tandem with constructivist pedagogies such as explicit pre-reading and a prior context of interactive lecturing. Data were collected through observation, via mobile phone voting in class and by an online survey designed to specifically explore the relationship between attendance at VotApedia lectures and factors such as self-reported engagement, attendance and preparation. The findings indicated that student response systems (SRSs are just as applicable to more Humanities-style disciplines which require divergent questioning, and supported complex interactions between engagement, attendance and preparation. Preliminary findings indicated that, although more work needs to be done, especially on the types of students who prefer to use these systems, there is a clear potential to increase student engagement in large law lectures through the use of SRSs.

  2. Effects of an instruction method in thinking skills with students from compulsory secondary education.

    Science.gov (United States)

    de Acedo Lizarraga, María Luisa Sanz; de Acedo Baquedano, María Teresa Sanz; Pollán Rufo, Milagros

    2010-05-01

    The purpose of this study was to assess the effects caused by the instruction method "Think actively in academic contexts, TAAC", an adaptation of Wallace and Adams' (1993) method of thinking skills, creativity, self-regulation, and academic learning, with students from the second grade of Compulsory Secondary Education (CSE). We used a pretest-intervention-posttest design with control group. The sample was made up of 110 participants, aged between 13 and 15 years, 58 of them in the experimental group and 52 in the control group. Six assessment instruments were administered before and after applying the method in order to measure the dependent variables. The method, divided into eight stages, was used in all the didactic units of the syllabus content of Natural Sciences, Social Sciences, and Language, during one academic course, and allowed the conjoint teaching of thinking skills and the syllabus content. The results of the analyses of variance indicate positive impact of the intervention, as the experimental subjects improved significantly in thinking skills and academic achievement. Some interesting reflections for research and education are derived from this study.

  3. Some Sociological Alternatives to Human Capital Theory and Their Implications for Research on Post-Compulsory Education and Training. Patterns of Participation in Adult Education and Training. Working Paper 3.

    Science.gov (United States)

    Fevre, Ralph

    This working paper is a product of a regional study in industrial South Wales of the determinants of participation and non-participation in post-compulsory education and training, with special reference to processes of change in the patterns of these determinants over time and to variations between geographical areas. Based on this data, three…

  4. Deep Incremental Boosting

    OpenAIRE

    Mosca, Alan; Magoulas, George D

    2017-01-01

    This paper introduces Deep Incremental Boosting, a new technique derived from AdaBoost, specifically adapted to work with Deep Learning methods, that reduces the required training time and improves generalisation. We draw inspiration from Transfer of Learning approaches to reduce the start-up time to training each incremental Ensemble member. We show a set of experiments that outlines some preliminary results on some common Deep Learning datasets and discuss the potential improvements Deep In...

  5. Science Potential of a Deep Ocean Antineutrino Observatory

    International Nuclear Information System (INIS)

    Dye, S.T.

    2007-01-01

    This paper presents science potential of a deep ocean antineutrino observatory being developed at Hawaii. The observatory design allows for relocation from one site to another. Positioning the observatory some 60 km distant from a nuclear reactor complex enables precision measurement of neutrino mixing parameters, leading to a determination of neutrino mass hierarchy and θ 13 . At a mid-Pacific location the observatory measures the flux and ratio of uranium and thorium decay neutrinos from earth's mantle and performs a sensitive search for a hypothetical natural fission reactor in earth's core. A subsequent deployment at another mid-ocean location would test lateral heterogeneity of uranium and thorium in earth's mantle

  6. Deep Super Learner: A Deep Ensemble for Classification Problems

    OpenAIRE

    Young, Steven; Abdou, Tamer; Bener, Ayse

    2018-01-01

    Deep learning has become very popular for tasks such as predictive modeling and pattern recognition in handling big data. Deep learning is a powerful machine learning method that extracts lower level features and feeds them forward for the next layer to identify higher level features that improve performance. However, deep neural networks have drawbacks, which include many hyper-parameters and infinite architectures, opaqueness into results, and relatively slower convergence on smaller datase...

  7. Effects of Precipitation on Ocean Mixed-Layer Temperature and Salinity as Simulated in a 2-D Coupled Ocean-Cloud Resolving Atmosphere Model

    Science.gov (United States)

    Li, Xiaofan; Sui, C.-H.; Lau, K-M.; Adamec, D.

    1999-01-01

    A two-dimensional coupled ocean-cloud resolving atmosphere model is used to investigate possible roles of convective scale ocean disturbances induced by atmospheric precipitation on ocean mixed-layer heat and salt budgets. The model couples a cloud resolving model with an embedded mixed layer-ocean circulation model. Five experiment are performed under imposed large-scale atmospheric forcing in terms of vertical velocity derived from the TOGA COARE observations during a selected seven-day period. The dominant variability of mixed-layer temperature and salinity are simulated by the coupled model with imposed large-scale forcing. The mixed-layer temperatures in the coupled experiments with 1-D and 2-D ocean models show similar variations when salinity effects are not included. When salinity effects are included, however, differences in the domain-mean mixed-layer salinity and temperature between coupled experiments with 1-D and 2-D ocean models could be as large as 0.3 PSU and 0.4 C respectively. Without fresh water effects, the nocturnal heat loss over ocean surface causes deep mixed layers and weak cooling rates so that the nocturnal mixed-layer temperatures tend to be horizontally-uniform. The fresh water flux, however, causes shallow mixed layers over convective areas while the nocturnal heat loss causes deep mixed layer over convection-free areas so that the mixed-layer temperatures have large horizontal fluctuations. Furthermore, fresh water flux exhibits larger spatial fluctuations than surface heat flux because heavy rainfall occurs over convective areas embedded in broad non-convective or clear areas, whereas diurnal signals over whole model areas yield high spatial correlation of surface heat flux. As a result, mixed-layer salinities contribute more to the density differences than do mixed-layer temperatures.

  8. How ocean lateral mixing changes Southern Ocean variability in coupled climate models

    Science.gov (United States)

    Pradal, M. A. S.; Gnanadesikan, A.; Thomas, J. L.

    2016-02-01

    The lateral mixing of tracers represents a major uncertainty in the formulation of coupled climate models. The mixing of tracers along density surfaces in the interior and horizontally within the mixed layer is often parameterized using a mixing coefficient ARedi. The models used in the Coupled Model Intercomparison Project 5 exhibit more than an order of magnitude range in the values of this coefficient used within the Southern Ocean. The impacts of such uncertainty on Southern Ocean variability have remained unclear, even as recent work has shown that this variability differs between different models. In this poster, we change the lateral mixing coefficient within GFDL ESM2Mc, a coarse-resolution Earth System model that nonetheless has a reasonable circulation within the Southern Ocean. As the coefficient varies from 400 to 2400 m2/s the amplitude of the variability varies significantly. The low-mixing case shows strong decadal variability with an annual mean RMS temperature variability exceeding 1C in the Circumpolar Current. The highest-mixing case shows a very similar spatial pattern of variability, but with amplitudes only about 60% as large. The suppression of mixing is larger in the Atlantic Sector of the Southern Ocean relatively to the Pacific sector. We examine the salinity budgets of convective regions, paying particular attention to the extent to which high mixing prevents the buildup of low-saline waters that are capable of shutting off deep convection entirely.

  9. DeepRT: deep learning for peptide retention time prediction in proteomics

    OpenAIRE

    Ma, Chunwei; Zhu, Zhiyong; Ye, Jun; Yang, Jiarui; Pei, Jianguo; Xu, Shaohang; Zhou, Ruo; Yu, Chang; Mo, Fan; Wen, Bo; Liu, Siqi

    2017-01-01

    Accurate predictions of peptide retention times (RT) in liquid chromatography have many applications in mass spectrometry-based proteomics. Herein, we present DeepRT, a deep learning based software for peptide retention time prediction. DeepRT automatically learns features directly from the peptide sequences using the deep convolutional Neural Network (CNN) and Recurrent Neural Network (RNN) model, which eliminates the need to use hand-crafted features or rules. After the feature learning, pr...

  10. Picocyanobacteria Dominance in Deep Biomass Layers: Relation to Diatom Presence and Episodic Events.

    Science.gov (United States)

    Aguilar, C.; Cuhel, R. L.

    2016-02-01

    In Offshore Marine and Large Lake Waters, most of the biomass and the productivity of phytoplankton occur below surface observation capabilities. Sub-mixed layer phytoplankton populations develop, increase, persist, and decay in relation to physical structure such as pycnocline density gradients interacting with progressively changing light fields. Basin-scale meteorological events and persistence of major invasive species have also left marks on biogeochemical cycling and ecosystem function in Lake Michigan. Among the former are precipitation and turbulence alterations brought on by unusual winter ice cover and a century-scale flood during 2008. Dampened seasonal silicate cycling indicated a basin-wide reduction of diatom production following mussel establishment. Communities in Lake Michigan shifted from diatom and big cell-dominated to small cell picocyanobacteria-dominated phytoplankton. Picocyanobacteria were beneficiaries of profound oligotrophication of the ecosystem starting in 2003. Photosynthetic parameters of pre-2003 Deep Biomass populations dominated by diatoms were systematically different from the cyanobacterial epoch following quagga mussel establishment and increase in depth of 1% incident light to 50-60m. Deep cyanobacterial production has now often been on the same scale as overlying waters. Photophysiology changes in a smooth depth gradient in this clear water as opposed to previous abrupt transition to shade adaptation. Among these many physicochemical permutations, community structure has consistently been a tradeoff between diatoms and picocyanobacteria. Opposing fluctuations of biomass favor one or the other on seasonal time frames of sequential years, with a complete system reset between each (winter mixing). For the Great Flood example, diatom surface blooms increased light extinction and drove the deep biomass maximum up - as populations settled into the pycnocline they had already outcompeted the picocyanobacteria. The opposite was true

  11. Deep Modeling: Circuit Characterization Using Theory Based Models in a Data Driven Framework

    Energy Technology Data Exchange (ETDEWEB)

    Bolme, David S [ORNL; Mikkilineni, Aravind K [ORNL; Rose, Derek C [ORNL; Yoginath, Srikanth B [ORNL; Holleman, Jeremy [University of Tennessee, Knoxville (UTK); Judy, Mohsen [University of Tennessee, Knoxville (UTK), Department of Electrical Engineering and Computer Science

    2017-01-01

    Analog computational circuits have been demonstrated to provide substantial improvements in power and speed relative to digital circuits, especially for applications requiring extreme parallelism but only modest precision. Deep machine learning is one such area and stands to benefit greatly from analog and mixed-signal implementations. However, even at modest precisions, offsets and non-linearity can degrade system performance. Furthermore, in all but the simplest systems, it is impossible to directly measure the intermediate outputs of all sub-circuits. The result is that circuit designers are unable to accurately evaluate the non-idealities of computational circuits in-situ and are therefore unable to fully utilize measurement results to improve future designs. In this paper we present a technique to use deep learning frameworks to model physical systems. Recently developed libraries like TensorFlow make it possible to use back propagation to learn parameters in the context of modeling circuit behavior. Offsets and scaling errors can be discovered even for sub-circuits that are deeply embedded in a computational system and not directly observable. The learned parameters can be used to refine simulation methods or to identify appropriate compensation strategies. We demonstrate the framework using a mixed-signal convolution operator as an example circuit.

  12. Impact of Parameterized Lateral Mixing on the Circulation of the Southern Ocean

    Science.gov (United States)

    Ragen, S.; Gnanadesikan, A.

    2016-02-01

    The Antarctic Circumpolar Current (ACC) is the strongest ocean current in the world, transporting approximately 130 Sv Eastward around Antarctica. This current is often poorly simulated in climate models. It is not clear why this is the case as the Circumpolar Current is affected by both wind and buoyancy. Changes in wind and buoyancy are not independent of each other, however, so determining the effects of both separately has proved difficult. This study was undertaken in order to examine the impact of changing the lateral diffusion coefficient A­redi on ACC transport. A­redi is poorly known and its value ranges across an order of magnitude in the current generation of climate models. To explore these dynamics, a coarse resolution, fully coupled model suite was run with A­redi mixing coefficients of 400 m2/s, 800 m2/s, 1200 m2/s, and 2400 m2/s. Additionally, two models were run with two-dimensional representations of the mixing coefficient based on altimetry. Our initial results indicate that higher values of the lateral mixing coefficient result in the following changes. We see weaker winds over the Southern Ocean as a whole. The high mixing case results in an 8.7% decrease in peak wind stress. We see a 2% weaker transport in the Drake Passage in the highest mixing case compared to the lowest, but an 11% decrease in transport for a zonal average. The change of temperature and salinity with depth with different Redi parameters also shows a significant difference between the Southern Ocean as a whole and the Drake Passage. Our findings seem to suggest that the Drake Passage is not an adequate diagnostic for explaining the differences between different climate models, as processes distant from the passage may play an important role. Observed changes in overturning with an increase in lateral mixing include an increase in northward transport of Antarctic Bottom Water fed by a small diversion of northern deep water inflows. This diversion means that less of the

  13. Bay Ridge Gardens - Mixed Humid Affordable Multifamily Housing Deep Energy Retrofit

    Energy Technology Data Exchange (ETDEWEB)

    Lyons, James [Building America Partnership for Improved Residential Construction (BA-PIRC), Cocoa, FL (United States); Moore, Mike [Building America Partnership for Improved Residential Construction (BA-PIRC), Cocoa, FL (United States); Thompson, Margo [Building America Partnership for Improved Residential Construction (BA-PIRC), Cocoa, FL (United States)

    2013-08-01

    Under this project, Newport Partners (as part of the BA-PIRC research team) evaluated the installation, measured performance, and cost effectiveness of efficiency upgrade measures for a tenant-in-place deep energy retrofit (DER) at the Bay Ridge multifamily development in Annapolis, Maryland. This report summarizes system commissioning, short-term test results, utility bill data analysis, and analysis of real-time data collected over a one-year period after the retrofit was complete. The Bay Ridge project is comprised of a "base scope" retrofit which was estimated to achieve a 30%+ savings (relative to pre-retrofit) on 186 apartments, and a "DER scope" which was estimated to achieve 50% savings (relative to pre-retrofit) on a 12-unit building. A wide range of efficiency measures was applied to pursue this savings target for the DER building, including improvements/replacements of mechanical equipment and distribution systems, appliances, lighting and lighting controls, the building envelope, hot water conservation measures, and resident education. The results of this research build upon the current body of knowledge of multifamily retrofits. Towards this end, the research team has collected and generated data on the selection of measures, their estimated performance, their measured performance, and risk factors and their impact on potential measures.

  14. Knowledge about the Greenhouse Effect and the Effects of the Ozone Layer among Norwegian Pupils Finishing Compulsory Education in 1989, 1993, and 2005 : What Now?

    OpenAIRE

    Hansen, Pål J. Kirkeby

    2010-01-01

    The greenhouse effect and the effects of the ozone layer have been in the media and public focus for more than two decades. During the same period, Norwegian compulsory schools have had four national curricula. The two last-mentioned prescribe explicitly the two topics. Media and public discourse might have been sources of information causing informal learning among pupils. The point of departure for this questionnaire-based examination of the development of pupils' knowledge about the greenh...

  15. Analyses of the deep borehole drilling status for a deep borehole disposal system

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong Youl; Choi, Heui Joo; Lee, Min Soo; Kim, Geon Young; Kim, Kyung Su [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    The purpose of disposal for radioactive wastes is not only to isolate them from humans, but also to inhibit leakage of any radioactive materials into the accessible environment. Because of the extremely high level and long-time scale radioactivity of HLW(High-level radioactive waste), a mined deep geological disposal concept, the disposal depth is about 500 m below ground, is considered as the safest method to isolate the spent fuels or high-level radioactive waste from the human environment with the best available technology at present time. Therefore, as an alternative disposal concept, i.e., deep borehole disposal technology is under consideration in number of countries in terms of its outstanding safety and cost effectiveness. In this paper, the general status of deep drilling technologies was reviewed for deep borehole disposal of high level radioactive wastes. Based on the results of these review, very preliminary applicability of deep drilling technology for deep borehole disposal analyzed. In this paper, as one of key technologies of deep borehole disposal system, the general status of deep drilling technologies in oil industry, geothermal industry and geo scientific field was reviewed for deep borehole disposal of high level radioactive wastes. Based on the results of these review, the very preliminary applicability of deep drilling technology for deep borehole disposal such as relation between depth and diameter, drilling time and feasibility classification was analyzed.

  16. Geothermal heating, diapycnal mixing and the abyssal circulation

    Directory of Open Access Journals (Sweden)

    J. Emile-Geay

    2009-06-01

    Full Text Available The dynamical role of geothermal heating in abyssal circulation is reconsidered using three independent arguments. First, we show that a uniform geothermal heat flux close to the observed average (86.4 mW m−2 supplies as much heat to near-bottom water as a diapycnal mixing rate of ~10−4 m2 s−1 – the canonical value thought to be responsible for the magnitude of the present-day abyssal circulation. This parity raises the possibility that geothermal heating could have a dynamical impact of the same order. Second, we estimate the magnitude of geothermally-induced circulation with the density-binning method (Walin, 1982, applied to the observed thermohaline structure of Levitus (1998. The method also allows to investigate the effect of realistic spatial variations of the flux obtained from heatflow measurements and classical theories of lithospheric cooling. It is found that a uniform heatflow forces a transformation of ~6 Sv at σ4=45.90, which is of the same order as current best estimates of AABW circulation. This transformation can be thought of as the geothermal circulation in the absence of mixing and is very similar for a realistic heatflow, albeit shifted towards slightly lighter density classes. Third, we use a general ocean circulation model in global configuration to perform three sets of experiments: (1 a thermally homogenous abyssal ocean with and without uniform geothermal heating; (2 a more stratified abyssal ocean subject to (i no geothermal heating, (ii a constant heat flux of 86.4 mW m−2, (iii a realistic, spatially varying heat flux of identical global average; (3 experiments (i and (iii with enhanced vertical mixing at depth. Geothermal heating and diapycnal mixing are found to interact non-linearly through the density field, with geothermal heating eroding the deep stratification supporting a downward diffusive flux, while diapycnal mixing acts to map

  17. Simulation of Deep Water Renewal in Crater Lake, Oregon, USA under Current and Future Climate Conditions

    Science.gov (United States)

    Piccolroaz, S.; Wood, T. M.; Wherry, S.; Girdner, S.

    2015-12-01

    We applied a 1-dimensional lake model developed to simulate deep mixing related to thermobaric instabilities in temperate lakes to Crater Lake, a 590-m deep caldera lake in Oregon's Cascade Range known for its stunning deep blue color and extremely clear water, in order to determine the frequency of deep water renewal in future climate conditions. The lake model was calibrated with 6 years of water temperature profiles, and then simulated 10 years of validation data with an RMSE ranging from 0.81°C at 50 m depth to 0.04°C at 350-460 m depth. The simulated time series of heat content in the deep lake accurately captured extreme years characterized by weak and strong deep water renewal. The lake model uses wind speed and lake surface temperature (LST) as boundary conditions. LST projections under six climate scenarios from the CMIP5 intermodel comparison project (2 representative concentration pathways X 3 general circulation models) were evaluated with air2water, a simple lumped model that only requires daily values of downscaled air temperature. air2water was calibrated with data from 1993-2011, resulting in a RMSE between simulated and observed daily LST values of 0.68°C. All future climate scenarios project increased water temperature throughout the water column and a substantive reduction in the frequency of deepwater renewal events. The least extreme scenario (CNRM-CM5, RCP4.5) projects the frequency of deepwater renewal events to decrease from about 1 in 2 years in the present to about 1 in 3 years by 2100. The most extreme scenario (HadGEM2-ES, RCP8.5) projects the frequency of deepwater renewal events to be less than 1 in 7 years by 2100 and lake surface temperatures never cooling to less than 4°C after 2050. In all RCP4.5 simulations the temperature of the entire water column is greater than 4°C for increasing periods of time. In the RCP8.5 simulations, the temperature of the entire water column is greater than 4°C year round by the year 2060 (HadGEM2

  18. Efficacy of a compulsory homework programme for increasing physical activity and healthy eating in children: the healthy homework pilot study

    Directory of Open Access Journals (Sweden)

    Duncan Scott

    2011-11-01

    Full Text Available Abstract Background Most physical activity and nutrition interventions in children focus on the school setting; however, evidence suggests that children are less active and have greater access to unhealthy food at home. The aim of this pilot study was to examine the efficacy of a compulsory homework programme for increasing physical activity and healthy eating in children. Methods The six-week 'Healthy Homework' programme and complementary teaching resource was developed under the guidance of an intersectoral steering group. Eight senior classes (year levels 5-6 from two diverse Auckland primary schools were randomly assigned into intervention and control groups. A total of 97 children (57 intervention, 40 control aged 9-11 years participated in the evaluation of the intervention. Daily step counts were monitored immediately before and after the intervention using sealed multiday memory pedometers. Screen time, sports participation, active transport to and from school, and the consumption of fruits, vegetables, unhealthy foods and drinks were recorded concurrently in a 4-day food and activity diary. Results Healthy Homework resulted in a significant intervention effect of 2,830 steps.day-1 (95% CI: 560, 5,300, P = 0.013. This effect was consistent between sexes, schools, and day types (weekdays and weekend days. In addition, significant intervention effects were observed for vegetable consumption (0.83 servings.day-1, 95% CI: 0.24, 1.43, P = 0.007 and unhealthy food consumption (-0.56 servings.day-1, 95% CI: -1.05, -0.07, P = 0.027 on weekends but not weekdays, with no interactions with sex or school. Effects for all other variables were not statistically significant regardless of day type. Conclusions Compulsory health-related homework appears to be an effective approach for increasing physical activity and improving vegetable and unhealthy food consumption in children. Further research in a larger study is required to confirm these initial

  19. Deep Space Telecommunications

    Science.gov (United States)

    Kuiper, T. B. H.; Resch, G. M.

    2000-01-01

    The increasing load on NASA's deep Space Network, the new capabilities for deep space missions inherent in a next-generation radio telescope, and the potential of new telescope technology for reducing construction and operation costs suggest a natural marriage between radio astronomy and deep space telecommunications in developing advanced radio telescope concepts.

  20. Greedy Deep Dictionary Learning

    OpenAIRE

    Tariyal, Snigdha; Majumdar, Angshul; Singh, Richa; Vatsa, Mayank

    2016-01-01

    In this work we propose a new deep learning tool called deep dictionary learning. Multi-level dictionaries are learnt in a greedy fashion, one layer at a time. This requires solving a simple (shallow) dictionary learning problem, the solution to this is well known. We apply the proposed technique on some benchmark deep learning datasets. We compare our results with other deep learning tools like stacked autoencoder and deep belief network; and state of the art supervised dictionary learning t...

  1. DeepBipolar: Identifying genomic mutations for bipolar disorder via deep learning.

    Science.gov (United States)

    Laksshman, Sundaram; Bhat, Rajendra Rana; Viswanath, Vivek; Li, Xiaolin

    2017-09-01

    Bipolar disorder, also known as manic depression, is a brain disorder that affects the brain structure of a patient. It results in extreme mood swings, severe states of depression, and overexcitement simultaneously. It is estimated that roughly 3% of the population of the United States (about 5.3 million adults) suffers from bipolar disorder. Recent research efforts like the Twin studies have demonstrated a high heritability factor for the disorder, making genomics a viable alternative for detecting and treating bipolar disorder, in addition to the conventional lengthy and costly postsymptom clinical diagnosis. Motivated by this study, leveraging several emerging deep learning algorithms, we design an end-to-end deep learning architecture (called DeepBipolar) to predict bipolar disorder based on limited genomic data. DeepBipolar adopts the Deep Convolutional Neural Network (DCNN) architecture that automatically extracts features from genotype information to predict the bipolar phenotype. We participated in the Critical Assessment of Genome Interpretation (CAGI) bipolar disorder challenge and DeepBipolar was considered the most successful by the independent assessor. In this work, we thoroughly evaluate the performance of DeepBipolar and analyze the type of signals we believe could have affected the classifier in distinguishing the case samples from the control set. © 2017 Wiley Periodicals, Inc.

  2. Deep learning? What deep learning? | Fourie | South African ...

    African Journals Online (AJOL)

    In teaching generally over the past twenty years, there has been a move towards teaching methods that encourage deep, rather than surface approaches to learning. The reason for this being that students, who adopt a deep approach to learning are considered to have learning outcomes of a better quality and desirability ...

  3. The Mechanism of First Raindrops Formation in Deep Convective Clouds

    Energy Technology Data Exchange (ETDEWEB)

    Khain, Alexander; Prabha, Thara; Benmoshe, Nir; Pandithurai, G.; Ovchinnikov, Mikhail

    2013-08-22

    The formation of first raindrops in deep convective clouds is investigated. A combination of observational data analysis and 2-D and 3-D numerical bin microphysical simulations of deep convective clouds suggests that the first raindrops form at the top of undiluted or slightly diluted cores. It is shown that droplet size distributions in these regions are wider and contain more large droplets than in diluted volumes. The results of the study indicate that the initial raindrop formation is determined by the basic microphysical processes within ascending adiabatic volumes. It allows one to predict the height of the formation of first raindrops considering the processes of nucleation, diffusion growth and collisions. The results obtained in the study explain observational results reported by Freud and Rosenfeld (2012) according to which the height of first raindrop formation depends linearly on the droplet number concentration at cloud base. The results also explain why a simple adiabatic parcel model can reproduce this dependence. The present study provides a physical basis for retrieval algorithms of cloud microphysical properties and aerosol properties using satellites proposed by Rosenfeld et al. ( 2012). The study indicates that the role of mixing and entrainment in the formation of the first raindrops is not of crucial importance. It is also shown that low variability of effective and mean volume radii along horizontal traverses, as regularly observed by in situ measurements, can be simulated by high-resolution cloud models, in which mixing is parameterized by a traditional 1.5 order turbulence closure scheme.

  4. DeepInfer: open-source deep learning deployment toolkit for image-guided therapy

    Science.gov (United States)

    Mehrtash, Alireza; Pesteie, Mehran; Hetherington, Jorden; Behringer, Peter A.; Kapur, Tina; Wells, William M.; Rohling, Robert; Fedorov, Andriy; Abolmaesumi, Purang

    2017-03-01

    Deep learning models have outperformed some of the previous state-of-the-art approaches in medical image analysis. Instead of using hand-engineered features, deep models attempt to automatically extract hierarchical representations at multiple levels of abstraction from the data. Therefore, deep models are usually considered to be more flexible and robust solutions for image analysis problems compared to conventional computer vision models. They have demonstrated significant improvements in computer-aided diagnosis and automatic medical image analysis applied to such tasks as image segmentation, classification and registration. However, deploying deep learning models often has a steep learning curve and requires detailed knowledge of various software packages. Thus, many deep models have not been integrated into the clinical research work ows causing a gap between the state-of-the-art machine learning in medical applications and evaluation in clinical research procedures. In this paper, we propose "DeepInfer" - an open-source toolkit for developing and deploying deep learning models within the 3D Slicer medical image analysis platform. Utilizing a repository of task-specific models, DeepInfer allows clinical researchers and biomedical engineers to deploy a trained model selected from the public registry, and apply it to new data without the need for software development or configuration. As two practical use cases, we demonstrate the application of DeepInfer in prostate segmentation for targeted MRI-guided biopsy and identification of the target plane in 3D ultrasound for spinal injections.

  5. Science Potential of a Deep Ocean Antineutrino Observatory

    Energy Technology Data Exchange (ETDEWEB)

    Dye, S.T. [Department of Physics and Astronomy, University of Hawaii, 2505 Correa Road, Honolulu, Hawaii, 96822 (United States); College of Natural Sciences, Hawaii Pacific University, 45-045 Kamehameha Highway, Kaneohe, Hawaii 96744 (United States)

    2007-06-15

    This paper presents science potential of a deep ocean antineutrino observatory being developed at Hawaii. The observatory design allows for relocation from one site to another. Positioning the observatory some 60 km distant from a nuclear reactor complex enables precision measurement of neutrino mixing parameters, leading to a determination of neutrino mass hierarchy and {theta}{sub 13}. At a mid-Pacific location the observatory measures the flux and ratio of uranium and thorium decay neutrinos from earth's mantle and performs a sensitive search for a hypothetical natural fission reactor in earth's core. A subsequent deployment at another mid-ocean location would test lateral heterogeneity of uranium and thorium in earth's mantle.

  6. Inter-comparison of stratospheric mean-meridional circulation and eddy mixing among six reanalysis data sets

    Directory of Open Access Journals (Sweden)

    K. Miyazaki

    2016-05-01

    Full Text Available The stratospheric mean-meridional circulation (MMC and eddy mixing are compared among six meteorological reanalysis data sets: NCEP-NCAR, NCEP-CFSR, ERA-40, ERA-Interim, JRA-25, and JRA-55 for the period 1979–2012. The reanalysis data sets produced using advanced systems (i.e., NCEP-CFSR, ERA-Interim, and JRA-55 generally reveal a weaker MMC in the Northern Hemisphere (NH compared with those produced using older systems (i.e., NCEP/NCAR, ERA-40, and JRA-25. The mean mixing strength differs largely among the data products. In the NH lower stratosphere, the contribution of planetary-scale mixing is larger in the new data sets than in the old data sets, whereas that of small-scale mixing is weaker in the new data sets. Conventional data assimilation techniques introduce analysis increments without maintaining physical balance, which may have caused an overly strong MMC and spurious small-scale eddies in the old data sets. At the NH mid-latitudes, only ERA-Interim reveals a weakening MMC trend in the deep branch of the Brewer–Dobson circulation (BDC. The relative importance of the eddy mixing compared with the mean-meridional transport in the subtropical lower stratosphere shows increasing trends in ERA-Interim and JRA-55; this together with the weakened MMC in the deep branch may imply an increasing age-of-air (AoA in the NH middle stratosphere in ERA-Interim. Overall, discrepancies between the different variables and trends therein as derived from the different reanalyses are still relatively large, suggesting that more investments in these products are needed in order to obtain a consolidated picture of observed changes in the BDC and the mechanisms that drive them.

  7. Powering up the biogeochemical engine: The impact of exceptional ventilation of a deep meromictic lake on the lacustrine redox, nutrient, and methane balances

    Directory of Open Access Journals (Sweden)

    Moritz Felix Lehmann

    2015-08-01

    Full Text Available The Lake Lugano North Basin has been meromictic for several decades, with anoxic waters below 100m depth. Two consecutive cold winters in 2005 and 2006 induced exceptional deep mixing, leading to a transient oxygenation of the whole water column. With the ventilation of deep waters and the oxidation of large quantities of reduced solutes, the lake's total redox-balance turned positive, and the overall hypolimnetic oxygen demand of the lake strongly decreased. The disappearance of 150 t dissolved phosphorous (P during the first ventilation in March 2005 is attributed to the scavenging of water-column-borne P by newly formed metal oxyhydroxides and the temporary transfer to the sediments. The fixed nitrogen (N inventory was reduced by ~30% (~1000 t. The water-column turnover induced the nitratation of the previously NO3--free deep hypolimnion by oxidation of large amounts of legacy NH4+ and by mixing with NO3--rich subsurface water masses. Sediments with a strong denitrifying potential, but NO3--starved for decades, were brought in contact with NO3--replete waters, invigorating benthic denitrification and rapid fixed N loss from the lake in spite of the overall more oxygenated conditions. Similarly, a large microbial aerobic CH4 oxidation (MOx potential in the hypolimnion was capitalized with the ventilation of the deep basin. Almost all CH4, which had been built up over more than 40 years (~2800 t, was removed from the water column within 30 days. However, boosted MOx could only partly explain the disappearance of the CH4. The dominant fraction (75% of the CH4 evaded to the atmosphere, through storage flux upon exposure of anoxic CH4-rich water to the atmosphere. As of today, the North Basin seems far from homeostasis regarding its fixed N and CH4 budgets, and the deep basin's CH4 pool is recharging at a net production rate of ~66 t y-1. The size of impending CH4 outbursts will depend on the frequency and intensity of exceptional mixing events in

  8. Evaluation of the radioactive wastes disposal into the deep ocean

    International Nuclear Information System (INIS)

    Aoyama, I.; Yamamoto, M.; Inoue, Y.

    1977-01-01

    A hazard assessment for deep sea disposal of low level radioactive solid wastes which originate from nuclear power reactors in Japan is presented. The model takes account of leaching characteristics of radionuclides from wastes solidified with cement, which has not been considered in other papers. Maximum and average concentrations of radionuclides in an upper mixed layer of the sea are estimated and maximum doses for individual and population doses for Japanese people are calculated. In order to evaluate an uncertainty of parameters in the model, a sensitivity analysis was performed. The discussions include: which parameter in an equation of the model affects most the average concentration of radionuclides in the upper mixed layer and, to what degree the fluctuation of parameters due to the variation of environmental factors affects the concentration. Generally, the most sensitive parameter is the depth of the seas where the solidified wastes would be deposited. The concentration of radionuclides in the surface water is not sensitively affected by the vertical diffusion coefficient. (author)

  9. Albedo Neutron Dosimetry in a Deep Geological Disposal Repository for High-Level Nuclear Waste.

    Science.gov (United States)

    Pang, Bo; Becker, Frank

    2017-04-28

    Albedo neutron dosemeter is the German official personal neutron dosemeter in mixed radiation fields where neutrons contribute to personal dose. In deep geological repositories for high-level nuclear waste, where neutrons can dominate the radiation field, it is of interest to investigate the performance of albedo neutron dosemeter in such facilities. In this study, the deep geological repository is represented by a shielding cask loaded with spent nuclear fuel placed inside a rock salt emplacement drift. Due to the backscattering of neutrons in the drift, issues concerning calibration of the dosemeter arise. Field-specific calibration of the albedo neutron dosemeter was hence performed with Monte Carlo simulations. In order to assess the applicability of the albedo neutron dosemeter in a deep geological repository over a long time scale, spent nuclear fuel with different ages of 50, 100 and 500 years were investigated. It was found out, that the neutron radiation field in a deep geological repository can be assigned to the application area 'N1' of the albedo neutron dosemeter, which is typical in reactors and accelerators with heavy shielding. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  10. Re-sampling of the KLX02 deep borehole at Laxemar

    International Nuclear Information System (INIS)

    Laaksoharju, M.; Andersson, Cecilia; Tullborg, E.L.; Wallin, B.; Ekwall, K.; Pedersen, K.

    1999-01-01

    The project focuses on the origin and changes of deep groundwaters, which are important for understanding the stability of the groundwater surrounding the final repository. The results from the sampling campaign in 1997 down to a depth of 1500m are compared with the results from 1993 sampled in the same borehole. The analytical results and some preliminary calculations are presented. The changes since the last sampling campaign 4 years ago indicate a high degree of mixing and dynamics in the system. The following conclusions are drawn: More changes in the water composition than expected compared with the results from the sampling campaign in 1993; Larger portions of meteoric water in the upper part of the borehole; Less glacial water in the intermediate part of the borehole; More brine water in the lower part of the borehole. The conclusion is that there has been a relatively large change in the groundwater system during the last 4 years in the Laxemar deep borehole. The disturbance removed the effect from the last glaciation and pulled in groundwater, which resulted in a mixture mainly consisting of meteoric and brine waters. The most probable reason is that the annual fluctuation and flow in the open borehole play an important role as a modificator especially for the isotopes. The results show the sensitivity of deep groundwater to changes in the prevailing hydrogeological situation

  11. Geochemistry of coal-measure source rocks and natural gases in deep formations in Songliao Basin, NE China

    Energy Technology Data Exchange (ETDEWEB)

    Mi, Jingkui; Zhang, Shuichang; Hu, Guoyi; He, Kun [State Key Laboratory for Enhanced Oil Recovery, Beijing (China); Petroleum Geology Research and Laboratory Center, Research Institute of Petroleum Exploration and Development, PetroChina (China); Key Laboratory for Petroleum Geochemistry, China National Petroleum Corp. (China)

    2010-12-01

    The natural gases developed in deep volcanic rock reservoirs of the Songliao Basin, NE China are characterized by enriched {delta}{sup 13}C value for methane and frequently reversal carbon isotopic distribution pattern. Although many researchers consider such gas type as an abiogenic origin, we believe the natural gases have a biogenic origin mainly except little inorganic gases and the reversal carbon isotopic distribution pattern of gases is caused by mixing of different origin gases. Methane carbon isotopic values for majority samples fall in the range from - 24 permille to - 32 permille, which is heavier than typical coal-type gases in other Chinese basins. There are several reasons caused heavy carbon isotope of methane: (1) Carbon isotopic values of source kerogen are 3-5 permille heavier than these from other basins; (2) Source rocks are at extremely high maturity stage with vitrinite reflectance mostly above 3.0%; (3) Portion of gas is derived from basement mudrock or slate with higher maturity. The observation on the organic from deep formation reveals that there is a relatively high content for liptinite, which reaches approximately 8 to 10%. The macerals component of source rock shows that the source rocks have some ability to generate oil. Small portion of oil was generated from high hydrogen content macerals in coals and shales as proof by oil found in microcrack and in micropore of coal and oil-bearing fluid inclusions grown in volcanic reservoir. The occurrence of pyrobitumen in volcanic reservoir indicates preexisted oil had been cracked into wet gas, and this kind of gas had also been found in gas pools. Heavy isotopic methane is derived from coal at extremely high maturity stage. There may be little inorganic alkane gases in deep layers for their geochemistry and special geological setting of Songliao Basin. Artificial mixing experiments of different origins gases confirm that inorganic gas such as gas from well FS1 mixed with other end members

  12. Deep learning with Python

    CERN Document Server

    Chollet, Francois

    2018-01-01

    DESCRIPTION Deep learning is applicable to a widening range of artificial intelligence problems, such as image classification, speech recognition, text classification, question answering, text-to-speech, and optical character recognition. Deep Learning with Python is structured around a series of practical code examples that illustrate each new concept introduced and demonstrate best practices. By the time you reach the end of this book, you will have become a Keras expert and will be able to apply deep learning in your own projects. KEY FEATURES • Practical code examples • In-depth introduction to Keras • Teaches the difference between Deep Learning and AI ABOUT THE TECHNOLOGY Deep learning is the technology behind photo tagging systems at Facebook and Google, self-driving cars, speech recognition systems on your smartphone, and much more. AUTHOR BIO Francois Chollet is the author of Keras, one of the most widely used libraries for deep learning in Python. He has been working with deep neural ...

  13. Deep learning evaluation using deep linguistic processing

    OpenAIRE

    Kuhnle, Alexander; Copestake, Ann

    2017-01-01

    We discuss problems with the standard approaches to evaluation for tasks like visual question answering, and argue that artificial data can be used to address these as a complement to current practice. We demonstrate that with the help of existing 'deep' linguistic processing technology we are able to create challenging abstract datasets, which enable us to investigate the language understanding abilities of multimodal deep learning models in detail, as compared to a single performance value ...

  14. In-situ stabilization of mixed waste contaminated soil

    International Nuclear Information System (INIS)

    Siegrist, R.L.; Cline, S.R.; Gilliam, T.M.; Conner, J.R.

    1993-01-01

    A full-scale field demonstration was conducted to evaluate in for stabilizing an inactive RCRA land treatment site at a DOE facility in Ohio. Subsurface silt and clay deposits were contaminated principally with up to 500 mg/kg of trichloroethylene and other halocarbons, but also trace to low levels of Pb, Cr, 235 U, and 99 Tc. In situ solidification was studied in three, 3.1 m diameter by 4.6 m deep columns. During mixing, a cement-based grout was injected and any missions from the mixed region were captured in a shroud and treated by filtration and carbon adsorption. During in situ processing, operation and performance parameters were measured, and soil cores were obtained from a solidified column 15 months later. Despite previous site-specific treatability experience, there were difficulties in selecting a grout with the requisite treatment agents amenable to subsurface injection and at a volume adequate for distribution throughout the mixed region while minimizing volume expansion. observations during the demonstration revealed that in situ solidification was rapidly accomplished (e.g., >90 m 3 /d) with limited emissions of volatile organics (i.e., -6 cm/s vs. 10 -8 cm/s). Leaching tests performed on the treated samples revealed non-detectable to acceptably low concentrations of all target contaminants

  15. Three-Dimensional Effects of Artificial Mixing in a Shallow Drinking-Water Reservoir

    Science.gov (United States)

    Chen, Shengyang; Little, John C.; Carey, Cayelan C.; McClure, Ryan P.; Lofton, Mary E.; Lei, Chengwang

    2018-01-01

    Studies that examine the effects of artificial mixing for water-quality mitigation in lakes and reservoirs often view a water column with a one-dimensional (1-D) perspective (e.g., homogenized epilimnetic and hypolimnetic layers). Artificial mixing in natural water bodies, however, is inherently three dimensional (3-D). Using a 3-D approach experimentally and numerically, the present study visualizes thermal structure and analyzes constituent transport under the influence of artificial mixing in a shallow drinking-water reservoir. The purpose is to improve the understanding of artificial mixing, which may help to better design and operate mixing systems. In this reservoir, a side-stream supersaturation (SSS) hypolimnetic oxygenation system and an epilimnetic bubble-plume mixing (EM) system were concurrently deployed in the deep region. The present study found that, while the mixing induced by the SSS system does not have a distinct 3-D effect on the thermal structure, epilimnetic mixing by the EM system causes 3-D heterogeneity. In the experiments, epilimnetic mixing deepened the lower metalimnetic boundary near the diffuser by about 1 m, with 55% reduction of the deepening rate at 120 m upstream of the diffuser. In a tracer study using a 3-D hydrodynamic model, the operational flow rate of the EM system is found to be an important short-term driver of constituent transport in the reservoir, whereas the duration of the EM system operation is the dominant long-term driver. The results suggest that artificial mixing substantially alters both 3-D thermal structure and constituent transport, and thus needs to be taken into account for reservoir management.

  16. The Sinking and Spreading of The Antarctic Deep Ice Shelf Water In The Ross Sea Studied By In Situ Observaions and Numerical Modeling

    Science.gov (United States)

    Rubino, A.; Budillon, G.; Pierini, S.; Spezie, G.

    The sinking and spreading of the Deep Ice Shelf Water (DISW) in the Ross Sea are analyzed using in situ observations and the results of a nonlinear, reduced-gravity, frontal layered numerical "plume" model which is able to simulate the motion of a bottom-arrested current over realistic topography. The model is forced by prescribing the thickness of the DISW vein as well as its density structure at the southern model boundary. The ambient temperature and salinity are imposed using hydrographic data acquired by the Italian PNRA-CLIMA project. In the model water of the quiescent ambient ocean is allowed to entrain in the active deep layer due to a simple param- eterization of turbulent mixing. The importance of forcing the model with a realistic ambient density is demonstrated by carrying out a numerical simulation in which the bottom active layer is forced using an idealized ambient density. In a more realis- tic simulation the path and the density structure of the DISW vein flowing over the Challenger Basin are obtained and are found to be in good agreement with data. The evolution of the deep current beyond the continental shelf is also simulated. It provides useful information on the water flow and mixing in a region of the Ross Sea where the paucity of experimental data does not allow for a detailed description of the deep ocean dynamics.

  17. Storm-driven Mixing and Potential Impact on the Arctic Ocean

    Science.gov (United States)

    Yang, Jiayan; Comiso, Josefino; Walsh, David; Krishfield, Richard; Honjo, Susumu; Koblinsky, Chester J. (Technical Monitor)

    2001-01-01

    Observations of the ocean, atmosphere, and ice made by Ice-Ocean Environmental Buoys (IOEBs) indicate that mixing events reaching the depth of the halocline have occurred in various regions in the Arctic Ocean. Our analysis suggests that these mixing events were mechanically forced by intense storms moving across the buoy sites. In this study, we analyzed these mixing events in the context of storm developments that occurred in the Beaufort Sea and in the general area just north of Fram Strait, two areas with quite different hydrographic structures. The Beaufort Sea is strongly influenced by inflow of Pacific water through Bering Strait, while the area north of Fram Strait is directly affected by the inflow of warm and salty North Atlantic water. Our analyses of the basin-wide evolution of the surface pressure and geostrophic wind fields indicate that the characteristics of the storms could be very different. The buoy-observed mixing occurred only in the spring and winter seasons when the stratification was relatively weak. This indicates the importance of stratification, although the mixing itself was mechanically driven. We also analyze the distribution of storms, both the long-term climatology as well as the patterns for each year in the last two decades. The frequency of storms is also shown to be correlated- (but not strongly) to Arctic Oscillation indices. This study indicates that the formation of new ice that leads to brine rejection is unlikely the mechanism that results in the type of mixing that could overturn the halocline. On the other hand, synoptic-scale storms can force mixing deep enough to the halocline and thermocline layer. Despite a very stable stratification associated with the Arctic halocline, the warm subsurface thermocline water is not always insulated from the mixed layer.

  18. [Nutricional adequacy of students of compulsory secondary education in Badajoz].

    Science.gov (United States)

    Córdoba-Caro, L G; Luego Pérez, L M; García Preciado, V

    2012-01-01

    To evaluate nutricional adequacy of students of compulsory secondary education (ESO) in Badajoz, Spain. We included 1197 students of ESO from 12 to 18 years old, 49.9% male and 50.1% female, which is a representative sample of this population. They filled in a food frequency questionnaire (FFQ) self-administered and previously validated in a pilot study. Nutrients were quantified from FFQ with a food composition table (Novartis, 2004) and nutritional Adequacy Index (AI) was calculated according to Spanish Recommended Dietary Allowances (RDA). Nutritional adequacy of a nutrient was measured by the following relation: mean daily intake of the nutrient / RDA of that nutrient * 100. Average caloric intake of secondary education students is not very high, protein AI is over 200%, and cholesterol over 150%, being appropriate the intake of carbohydrates and lipids. The intake of fiber, vitamin E and iodine was lower than 50% in both genders; the one of iron less than 90% in females and there were no other differences between both genders. Only 1% to 3% of students reach RDA of fiber, iodine and vitamin E, and 37.3% of female reach RDA of iron. Cholesterol dietary intake of 17.2% males and 25.3% females is high, and saturated fatty acids intake is high in 46.1% males and 50.0% females. Diet of students of secondary education in Badajoz is normocaloric, hyperproteic, appropriate in carbohydrates and lipids, without differences between genders; it is very deficient in fiber, iodine and vitamin E in both genders and deficient in iron in females. We can see their diet is far from Mediterranean diet, and this is why education plans about food intake are advised to the students and their families.

  19. Deep sequencing analysis of HBV genotype shift and correlation with antiviral efficiency during adefovir dipivoxil therapy.

    Directory of Open Access Journals (Sweden)

    Yuwei Wang

    Full Text Available Viral genotype shift in chronic hepatitis B (CHB patients during antiviral therapy has been reported, but the underlying mechanism remains elusive.38 CHB patients treated with ADV for one year were selected for studying genotype shift by both deep sequencing and Sanger sequencing method.Sanger sequencing method found that 7.9% patients showed mixed genotype before ADV therapy. In contrast, all 38 patients showed mixed genotype before ADV treatment by deep sequencing. 95.5% mixed genotype rate was also obtained from additional 200 treatment-naïve CHB patients. Of the 13 patients with genotype shift, the fraction of the minor genotype in 5 patients (38% increased gradually during the course of ADV treatment. Furthermore, responses to ADV and HBeAg seroconversion were associated with the high rate of genotype shift, suggesting drug and immune pressure may be key factors to induce genotype shift. Interestingly, patients with genotype C had a significantly higher rate of genotype shift than genotype B. In genotype shift group, ADV treatment induced a marked enhancement of genotype B ratio accompanied by a reduction of genotype C ratio, suggesting genotype C may be more sensitive to ADV than genotype B. Moreover, patients with dominant genotype C may have a better therapeutic effect. Finally, genotype shifts was correlated with clinical improvement in terms of ALT.Our findings provided a rational explanation for genotype shift among ADV-treated CHB patients. The genotype and genotype shift might be associated with antiviral efficiency.

  20. Efficacy evaluation of managed population shift in Ukraine from zone of obligate (compulsory) resettlement as a measure of public radiation protection

    International Nuclear Information System (INIS)

    Gun'ko, N.V.

    2015-01-01

    Evaluation of efficacy of the managed population transmigration from zone of obligate (compulsory) resettlement as a measure of civil protection after the Chernobyl NPP accident from the perspective of radiation biology. Materials and methods. Legislative and statutory-tutorial documents that regulate the managed population shift from radiologically contaminated territories of Ukraine and data from the Ukrainian State Service of Statistics on time limits and scopes of population transmigration from contaminated settlements were the informational back ground of the study. Data on retrospective and expected/anticipated radiation doses in population of settlements exposed to radiological contamination in Ukraine after the Chernobyl disaster summarized for the 1986-1997 period and up to 2055 were the information source for calculation of averted doses due to population shift. Battery of basic research empirical evidence review methods was applied under the calculation, systemic, and biomedical approach. Population shift from zone of obligate (compulsory) resettlement (hereafter referred to as Zone 2) to stop the radiation exposure as a tool of civil protection from emergency ionizing radiation after the Chernobyl NPP accident was scientifically substantiated and expedient from the perspective of radiation biology. Estimability of a managed population shift from 'dose-effect' perspective and 'benefit/harm' principle is worse because of data absence on individual radiation doses to migrants in the country. Public shift in 1990 and 1991 was most effective from the viewpoint of level of averted lifetime dose. Due to transmigration the averted lifetime dose to the most vulnerable group of the Chernobyl disaster survivors i.e. children aged 0 years varied from 11.2 to 28.8 mSv (calculated for the Perejizdiv village council of Zhytomyr province). Since 2000 there was almost no public shift being not accomplished in the scheduled scope. Delay and incompleteness of

  1. Connectivity between surface and deep waters determines prokaryotic diversity in the North Atlantic Deep Water.

    Science.gov (United States)

    Frank, Alexander H; Garcia, Juan A L; Herndl, Gerhard J; Reinthaler, Thomas

    2016-06-01

    To decipher the influence of depth stratification and surface provincialism on the dark ocean prokaryotic community composition, we sampled the major deep-water masses in the eastern North Atlantic covering three biogeographic provinces. Their diversity was evaluated using ordination and canonical analysis of 454 pyrotag sequences. Variance partitioning suggested that 16% of the variation in the bacterial community composition was based on depth stratification while 9% of the variation was due to geographic location. General linear mixed effect models showed that the community of the subsurface waters was connected to the dark ocean prokaryotic communities in different biogeographic provinces. Cluster analysis indicated that some prokaryotic taxa are specific to distinct regions in bathypelagic water masses. Taken together, our data suggest that the dark ocean prokaryotic community composition of the eastern North Atlantic is primed by the formation and the horizontal transport of water masses. © 2016 Society for Applied Microbiology and John Wiley & Sons Ltd.

  2. COOPERATION BETWEEN THE MINISTRY OF NATIONAL EDUCATION AND LOCAL SELF-GOVERNMENT BODIES OF THE PERM PROVINCE DURING THE PERIOD “PREPARATORY WORK FOR THE COMPULSORY EDUCATION INTRODUCTION”

    Directory of Open Access Journals (Sweden)

    S. V. Golikova

    2018-01-01

    Full Text Available Introduction. In the history of education, there is still considerable shortfall of the question on mechanisms realization of the general literacy idea in Russia in the beginning of the last century, which gained its popularity around the world at the turn of the 19–20th centuries. Meanwhile, the stage of preparation for cosmopolitan diffusion of compulsory primary education in the Russian Empire, marked by emergence of the special bill drafted by the Ministry of National Education in 1907, is of great interest to the research of opportunities of interaction of the state institutes and regional local self-government bodies (Zemstvo in the Russian language.The aim of the publication is to show the efficiency of joint activities of local self-government bodies and national administrative bodies with reference to example of the system of primary national education formation during 1908–1913 in the Perm province.Methodology and research methods. The methodological base of the present research is based on: the “center-periphery” conceptual model; methods of the retrospective chronological analysis, synthesis, generalization and interpretation of archival documents.Results and scientific novelty. The methodological perspective of studying the history of primary schools organization in pre-revolutionary Russia is proved. The choice of regional (provincial scale of this process enables to consider features of the public educational policy at the subcountry level; the center-periphery approach to the discussed subject makes it possible to understand more deeply the essence and purposes of the major educational reform. The assessment of the contents on the introduction of compulsory primary education in the Russian Empire is given; the draft bill established standards, new to educational practice, can be listed as follows: “normal duration of training”, “normal school age”, “normal number of children”, “normal school area” (

  3. DeepMitosis: Mitosis detection via deep detection, verification and segmentation networks.

    Science.gov (United States)

    Li, Chao; Wang, Xinggang; Liu, Wenyu; Latecki, Longin Jan

    2018-04-01

    Mitotic count is a critical predictor of tumor aggressiveness in the breast cancer diagnosis. Nowadays mitosis counting is mainly performed by pathologists manually, which is extremely arduous and time-consuming. In this paper, we propose an accurate method for detecting the mitotic cells from histopathological slides using a novel multi-stage deep learning framework. Our method consists of a deep segmentation network for generating mitosis region when only a weak label is given (i.e., only the centroid pixel of mitosis is annotated), an elaborately designed deep detection network for localizing mitosis by using contextual region information, and a deep verification network for improving detection accuracy by removing false positives. We validate the proposed deep learning method on two widely used Mitosis Detection in Breast Cancer Histological Images (MITOSIS) datasets. Experimental results show that we can achieve the highest F-score on the MITOSIS dataset from ICPR 2012 grand challenge merely using the deep detection network. For the ICPR 2014 MITOSIS dataset that only provides the centroid location of mitosis, we employ the segmentation model to estimate the bounding box annotation for training the deep detection network. We also apply the verification model to eliminate some false positives produced from the detection model. By fusing scores of the detection and verification models, we achieve the state-of-the-art results. Moreover, our method is very fast with GPU computing, which makes it feasible for clinical practice. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. Deep frying

    NARCIS (Netherlands)

    Koerten, van K.N.

    2016-01-01

    Deep frying is one of the most used methods in the food processing industry. Though practically any food can be fried, French fries are probably the most well-known deep fried products. The popularity of French fries stems from their unique taste and texture, a crispy outside with a mealy soft

  5. 224Ra distribution in surface and deep water of Long Island Sound: sources and horizontal transport rates

    International Nuclear Information System (INIS)

    Torgersen, T.; O'Donnell, J.; DeAngelo, E.; Turekian, K.K.; Turekian, V.C.; Tanaka, N.

    1997-01-01

    Measurements of surface water and deep water 224 Ra(half-life 3.64 days) distributions in Long Island Sound (LIS) were conducted in July 1991. Because the pycnocline structure of LIS had been in place for about 50 days in July (long compared to the half-life of 224 Ra) in the surface water and the deep water operate as separate systems. In the surface water, the fine-grain sediments of nearshore and saltmarsh environments provide a strong source of 224 Ra, which is horizontally mixed away from the short to central LIS. A one-dimensional model of 224 Ra distribution suggests a cross-LIS horizontal eddy dispersivity of 5-50 m 2 s -1 . In the deep water, the mid-LIS sediment flux of 224 Ra is enhanced by ∼ 2x relative to the periphery, and the horizontal eddy flux is from central LIS to the periphery. A second one-dimensional model suggests a cross-LIS horizontal eddy dispersivity below the thermocline of 5-50 m 2 -1 . 224 Ra fluxes into the deep water of the central LIS are likely enhanced by (1) inhomogeneous sediment or (2) a reduced scavenging of 224 Ra in the sediments of central LIS brought about by low oxygen conditions (hypoxia) and the loss of the MnO 2 scavenging layer in the sediments. These rates of horizontal eddy dispersivity are significantly less than the estimate of 100-650 m 2 s -1 (Riley, 1967) but are consistent with the transport necessary to explain the dynamics of oxygen depletion in summer LIS. These results demonstrate the use of 224 Ra for quantifying the parameters needed to describe estuarine mixing and transport. (Author)

  6. Sizable NSI from the SU(2){sub L} scalar doublet-singlet mixing and the implications in DUNE

    Energy Technology Data Exchange (ETDEWEB)

    Forero, David V. [Center for Neutrino Physics, Virginia Tech,Blacksburg, VA, 24061 (United States); Huang, Wei-Chih [Fakultät für Physik, Technische Universität Dortmund,Dortmund, 44221 (Germany)

    2017-03-03

    We propose a novel and simple mechanism where sizable effects of non-standard interactions (NSI) in neutrino propagation are induced from the mixing between an electrophilic second Higgs doublet and a charged singlet. The mixing arises from a dimensionful coupling of the scalar doublet and singlet to the standard model Higgs boson. In light of the small mass, the light mass eigenstate from the doublet-singlet mixing can generate much larger NSI than those induced by the heavy eigenstate. We show that a sizable NSI ε{sub eτ} (∼0.3) can be attained without being excluded by a variety of experimental constraints. Furthermore, we demonstrate that NSI can mimic effects of the Dirac CP phase in the neutrino mixing matrix but they can potentially be disentangled by future long-baseline neutrino experiments, such as the Deep Underground Neutrino Experiment (DUNE).

  7. DeepPVP: phenotype-based prioritization of causative variants using deep learning

    KAUST Repository

    Boudellioua, Imene

    2018-05-02

    Background: Prioritization of variants in personal genomic data is a major challenge. Recently, computational methods that rely on comparing phenotype similarity have shown to be useful to identify causative variants. In these methods, pathogenicity prediction is combined with a semantic similarity measure to prioritize not only variants that are likely to be dysfunctional but those that are likely involved in the pathogenesis of a patient\\'s phenotype. Results: We have developed DeepPVP, a variant prioritization method that combined automated inference with deep neural networks to identify the likely causative variants in whole exome or whole genome sequence data. We demonstrate that DeepPVP performs significantly better than existing methods, including phenotype-based methods that use similar features. DeepPVP is freely available at https://github.com/bio-ontology-research-group/phenomenet-vp Conclusions: DeepPVP further improves on existing variant prioritization methods both in terms of speed as well as accuracy.

  8. Design and construction of a deep slurry trench barrier

    International Nuclear Information System (INIS)

    Deming, P.W.

    1997-01-01

    A 24 m (80 ft) deep slurry trench surrounding a former chromium manufacturing facility on the Patapsco River in Baltimore, Maryland was constructed in 1995 to contain groundwater and site Soils, and to reduce the volume of groundwater extracted to maintain an inward gradient. In 1992, an embankment made of crushed stone was constructed in the Patapsco River to make land for barrier construction outboard of the bulkheads, and to protect the barrier. Stability of the slurry-supported trench excavation in the embankment required construction from an elevated work platform. An extended reach backhoe was used to excavate the deep slurry trench and to clean the trench bottom. Soil-Bentonite backfill was prepared at a central mixing area and transported by truck to the perimeter barrier. A synthetic membrane was inserted partially into the backfill for connection to a multimedia cap, and for redundancy and erosion control in the tidal zone. Hydraulic testing of the aquitard contained by the barrier demonstrated excellent performance of the barrier and bottom closure. Detailed definition of subsurface conditions and the closure stratum was necessary for the design and successful construction of the barrier, and is recommended for comparable slurry trench construction projects

  9. Hot, deep origin of petroleum: deep basin evidence and application

    Science.gov (United States)

    Price, Leigh C.

    1978-01-01

    Use of the model of a hot deep origin of oil places rigid constraints on the migration and entrapment of crude oil. Specifically, oil originating from depth migrates vertically up faults and is emplaced in traps at shallower depths. Review of petroleum-producing basins worldwide shows oil occurrence in these basins conforms to the restraints of and therefore supports the hypothesis. Most of the world's oil is found in the very deepest sedimentary basins, and production over or adjacent to the deep basin is cut by or directly updip from faults dipping into the basin deep. Generally the greater the fault throw the greater the reserves. Fault-block highs next to deep sedimentary troughs are the best target areas by the present concept. Traps along major basin-forming faults are quite prospective. The structural style of a basin governs the distribution, types, and amounts of hydrocarbons expected and hence the exploration strategy. Production in delta depocenters (Niger) is in structures cut by or updip from major growth faults, and structures not associated with such faults are barren. Production in block fault basins is on horsts next to deep sedimentary troughs (Sirte, North Sea). In basins whose sediment thickness, structure and geologic history are known to a moderate degree, the main oil occurrences can be specifically predicted by analysis of fault systems and possible hydrocarbon migration routes. Use of the concept permits the identification of significant targets which have either been downgraded or ignored in the past, such as production in or just updip from thrust belts, stratigraphic traps over the deep basin associated with major faulting, production over the basin deep, and regional stratigraphic trapping updip from established production along major fault zones.

  10. Deep learning in bioinformatics.

    Science.gov (United States)

    Min, Seonwoo; Lee, Byunghan; Yoon, Sungroh

    2017-09-01

    In the era of big data, transformation of biomedical big data into valuable knowledge has been one of the most important challenges in bioinformatics. Deep learning has advanced rapidly since the early 2000s and now demonstrates state-of-the-art performance in various fields. Accordingly, application of deep learning in bioinformatics to gain insight from data has been emphasized in both academia and industry. Here, we review deep learning in bioinformatics, presenting examples of current research. To provide a useful and comprehensive perspective, we categorize research both by the bioinformatics domain (i.e. omics, biomedical imaging, biomedical signal processing) and deep learning architecture (i.e. deep neural networks, convolutional neural networks, recurrent neural networks, emergent architectures) and present brief descriptions of each study. Additionally, we discuss theoretical and practical issues of deep learning in bioinformatics and suggest future research directions. We believe that this review will provide valuable insights and serve as a starting point for researchers to apply deep learning approaches in their bioinformatics studies. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  11. Heterogeneous distribution of plankton within the mixed layer and its implications for bloom formation in tropical seas

    KAUST Repository

    Calbet, Albert; Agersted, Mette Dalgaard; Kaartvedt, Stein; Mø hl, Malene; Mø ller, Eva Friis; Enghoff-Poulsen, Sø ren; Paulsen, Maria Lund; Solberg, Ingrid; Tang, Kam W.; Tonnesson, Kajsa; Raitsos, Dionysios E.; Nielsen, Torkel Gissel

    2015-01-01

    Intensive sampling at the coastal waters of the central Red Sea during a period of thermal stratification, prior to the main seasonal bloom during winter, showed that vertical patches of prokaryotes and microplankton developed and persisted for several days within the apparently density uniform upper layer. These vertical structures were most likely the result of in situ growth and mortality (e.g., grazing) rather than physical or behavioural aggregation. Simulating a mixing event by adding nutrient-rich deep water abruptly triggered dense phytoplankton blooms in the nutrient-poor environment of the upper layer. These findings suggest that vertical structures within the mixed layer provide critical seeding stocks that can rapidly exploit nutrient influx during mixing, leading to winter bloom formation.

  12. Heterogeneous distribution of plankton within the mixed layer and its implications for bloom formation in tropical seas

    KAUST Repository

    Calbet, Albert

    2015-06-11

    Intensive sampling at the coastal waters of the central Red Sea during a period of thermal stratification, prior to the main seasonal bloom during winter, showed that vertical patches of prokaryotes and microplankton developed and persisted for several days within the apparently density uniform upper layer. These vertical structures were most likely the result of in situ growth and mortality (e.g., grazing) rather than physical or behavioural aggregation. Simulating a mixing event by adding nutrient-rich deep water abruptly triggered dense phytoplankton blooms in the nutrient-poor environment of the upper layer. These findings suggest that vertical structures within the mixed layer provide critical seeding stocks that can rapidly exploit nutrient influx during mixing, leading to winter bloom formation.

  13. Heterogeneous distribution of plankton within the mixed layer and its implications for bloom formation in tropical seas

    DEFF Research Database (Denmark)

    Calbet, Albert; Agersted, Mette Dalgaard; Kaartvedt, Stein

    2015-01-01

    Intensive sampling at the coastal waters of the central Red Sea during a period of thermal stratification, prior to the main seasonal bloom during winter, showed that vertical patches of prokaryotes and microplankton developed and persisted for several days within the apparently density uniform...... upper layer. These vertical structures were most likely the result of in situ growth and mortality (e.g., grazing) rather than physical or behavioural aggregation. Simulating a mixing event by adding nutrient-rich deep water abruptly triggered dense phytoplankton blooms in the nutrient-poor environment...... of the upper layer. These findings suggest that vertical structures within the mixed layer provide critical seeding stocks that can rapidly exploit nutrient influx during mixing, leading to winter bloom formation...

  14. Importance of the variability of hydrographic preconditioning for deep convection in the Gulf of Lion, NW Mediterranean

    Directory of Open Access Journals (Sweden)

    L. Grignon

    2010-06-01

    Full Text Available We study the variability of hydrographic preconditioning defined as the heat and salt contents in the Ligurian Sea before convection. The stratification is found to reach a maximum in the intermediate layer in December, whose causes and consequences for the interannual variability of convection are investigated. Further study of the interannual variability and correlation tests between the properties of the deep water formed and the winter surface fluxes support the description of convection as a process that transfers the heat and salt contents from the top and intermediate layers to the deep layer. A proxy for the rate of transfer is given by the final convective mixed layer depth, that is shown to depend equally on the surface fluxes and on the preconditioning. In particular, it is found that deep convection in winter 2004–2005 would have happened even with normal winter conditions, due to low pre-winter stratification.

  15. DeepSimulator: a deep simulator for Nanopore sequencing

    KAUST Repository

    Li, Yu

    2017-12-23

    Motivation: Oxford Nanopore sequencing is a rapidly developed sequencing technology in recent years. To keep pace with the explosion of the downstream data analytical tools, a versatile Nanopore sequencing simulator is needed to complement the experimental data as well as to benchmark those newly developed tools. However, all the currently available simulators are based on simple statistics of the produced reads, which have difficulty in capturing the complex nature of the Nanopore sequencing procedure, the main task of which is the generation of raw electrical current signals. Results: Here we propose a deep learning based simulator, DeepSimulator, to mimic the entire pipeline of Nanopore sequencing. Starting from a given reference genome or assembled contigs, we simulate the electrical current signals by a context-dependent deep learning model, followed by a base-calling procedure to yield simulated reads. This workflow mimics the sequencing procedure more naturally. The thorough experiments performed across four species show that the signals generated by our context-dependent model are more similar to the experimentally obtained signals than the ones generated by the official context-independent pore model. In terms of the simulated reads, we provide a parameter interface to users so that they can obtain the reads with different accuracies ranging from 83% to 97%. The reads generated by the default parameter have almost the same properties as the real data. Two case studies demonstrate the application of DeepSimulator to benefit the development of tools in de novo assembly and in low coverage SNP detection. Availability: The software can be accessed freely at: https://github.com/lykaust15/DeepSimulator.

  16. Deep learning relevance

    DEFF Research Database (Denmark)

    Lioma, Christina; Larsen, Birger; Petersen, Casper

    2016-01-01

    train a Recurrent Neural Network (RNN) on existing relevant information to that query. We then use the RNN to "deep learn" a single, synthetic, and we assume, relevant document for that query. We design a crowdsourcing experiment to assess how relevant the "deep learned" document is, compared...... to existing relevant documents. Users are shown a query and four wordclouds (of three existing relevant documents and our deep learned synthetic document). The synthetic document is ranked on average most relevant of all....

  17. Mesoscale mixing of the Denmark Strait Overflow in the Irminger Basin

    Science.gov (United States)

    Koszalka, Inga M.; Haine, Thomas W. N.; Magaldi, Marcello G.

    2017-04-01

    The Denmark Strait Overflow (DSO) is a major export route for dense waters from the Nordic Seas forming the lower limb of the Atlantic Meridional Overturning Circulation, an important element of the climate system. Mixing processes along the DSO pathway influence its volume transport and properties contributing to the variability of the deep overturning circulation. They are poorly sampled by observations, however, which hinders development of a proper DSO representation in global circulation models. We employ a high resolution regional ocean model of the Irminger Basin to quantify impact of the mesoscale flows on DSO mixing focusing on geographical localization and the time-modulation of water property changes. The model reproduces the observed bulk warming of the DSO plume 100-200 km downstream of the Denmark Strait sill. It also reveals that mesoscale variability of the overflow ('DSO-eddies', of 20-30 km extent and a time scale of 2-5 day) modulates water property changes and turbulent mixing, diagnosed with the vertical shear of horizontal velocity and the eddy heat flux divergence. The space-time localization of the DSO mixing and warming and the role of coherent mesoscale structures should be explored by turbulence measurements and factored into the coarse circulation models.

  18. STIMULATION TECHNOLOGIES FOR DEEP WELL COMPLETIONS

    Energy Technology Data Exchange (ETDEWEB)

    Stephen Wolhart

    2003-06-01

    The Department of Energy (DOE) is sponsoring a Deep Trek Program targeted at improving the economics of drilling and completing deep gas wells. Under the DOE program, Pinnacle Technologies is conducting a project to evaluate the stimulation of deep wells. The objective of the project is to assess U.S. deep well drilling & stimulation activity, review rock mechanics & fracture growth in deep, high pressure/temperature wells and evaluate stimulation technology in several key deep plays. Phase 1 was recently completed and consisted of assessing deep gas well drilling activity (1995-2007) and an industry survey on deep gas well stimulation practices by region. Of the 29,000 oil, gas and dry holes drilled in 2002, about 300 were drilled in the deep well; 25% were dry, 50% were high temperature/high pressure completions and 25% were simply deep completions. South Texas has about 30% of these wells, Oklahoma 20%, Gulf of Mexico Shelf 15% and the Gulf Coast about 15%. The Rockies represent only 2% of deep drilling. Of the 60 operators who drill deep and HTHP wells, the top 20 drill almost 80% of the wells. Six operators drill half the U.S. deep wells. Deep drilling peaked at 425 wells in 1998 and fell to 250 in 1999. Drilling is expected to rise through 2004 after which drilling should cycle down as overall drilling declines.

  19. Toward the Characterization of Mixed-Phase Clouds Using Remote Sensing

    Science.gov (United States)

    Andronache, C.

    2015-12-01

    Mixed-phase clouds consist of a mixture of ice particles and liquid droplets at temperatures below 0 deg C. They are present in all seasons in many regions of the world, account for about 30% of the global cloud coverage, and are linked to cloud electrification and aircraft icing. The mix of ice particles, liquid droplets, and water vapor is unstable, and such clouds are thought to have a short lifetime. A characteristic parameter is the phase composition of mixed-phase clouds. It affects the cloud life cycle and the rate of precipitation. This parameter is important for cloud parameters retrievals by radar, lidar, and satellite and is relevant for climate modeling. The phase transformation includes the remarkable Wegener-Bergeron-Findeisen (WBF) process. The direction and the rate of the phase transformations depend on the local thermodynamic and microphysical properties. Cloud condensation nuclei (CCN) and ice nuclei (IN) particles determine to a large extent cloud microstructure and the dynamic response of clouds to aerosols. The complexity of dynamics and microphysics involved in mixed-phase clouds requires a set of observational and modeling tools that continue to be refined. Among these techniques, the remote sensing methods provide an increasing number of parameters, covering large regions of the world. Thus, a series of studies were dedicated to stratiform mixed-phase clouds revealing longer lifetime than previously thought. Satellite data and aircraft in situ measurements in deep convective clouds suggest that highly supercooled water often occurs in vigorous continental convective storms. In this study, we use cases of convective clouds to discuss the feasibility of mixed-phase clouds characterization and potential advantages of remote sensing.

  20. Doenças dermatológicas de notificação compulsória no Brasil Dermatological diseases of compulsory notification in Brazil

    Directory of Open Access Journals (Sweden)

    Gerson Oliveira Penna

    2011-10-01

    Full Text Available A estruturação do Sistema Nacional de Vigilância Epidemiológica do Brasil, em 1975, tornou obrigatória a notificação de algumas doenças transmissíveis com o objetivo de reduzir a carga destes eventos no país. Entretanto, as alterações no perfil epidemiológico destas doenças, associadas a características da sociedade contemporânea, determinam a constante adequação das atividades de vigilância a este cenário. Neste manuscrito, são descritos epidemiologia, tendências e diagnóstico diferencial das seguintes doenças dermatológicas de notificação compulsória no Brasil: aids, dengue, hanseníase, leishmaniose tegumentar americana, sarampo, rubéola e síndrome da rubéola congênita e sífilis. Também são apresentados os principais desafios atuais para o controle e prevenção para cada uma dessas doenças no BrasilThe development of a Brazilian National Surveillance System in 1975 led to a compulsory reporting of selected infectious diseases aiming to reduce the burden of these events in the country. However, shifts in the epidemiology of these diseases associated with modern life style, demand constant revision of surveillance activities. In this manuscript we present the epidemiology, trends and differential diagnosis of the following compulsory notifiable diseases in Brazil: Aids, dengue fever, hanseniasis, American tegumentary leishmaniasis, measles, rubella and congenital rubella syndrome and syphilis. Additionally, the current challenges for control and prevention of each disease are presented

  1. Deep learning in TMVA Benchmarking Benchmarking TMVA DNN Integration of a Deep Autoencoder

    CERN Document Server

    Huwiler, Marc

    2017-01-01

    The TMVA library in ROOT is dedicated to multivariate analysis, and in partic- ular oers numerous machine learning algorithms in a standardized framework. It is widely used in High Energy Physics for data analysis, mainly to perform regression and classication. To keep up to date with the state of the art in deep learning, a new deep learning module was being developed this summer, oering deep neural net- work, convolutional neural network, and autoencoder. TMVA did not have yet any autoencoder method, and the present project consists in implementing the TMVA autoencoder class based on the deep learning module. It also includes some bench- marking performed on the actual deep neural network implementation, in comparison to the Keras framework with Tensorflow and Theano backend.

  2. Modeling the impact of the 7-valent pneumococcal conjugate vaccine in Chinese infants: an economic analysis of a compulsory vaccination.

    Science.gov (United States)

    Che, Datian; Zhou, Hua; He, Jinchun; Wu, Bin

    2014-02-07

    The purpose of this study was to compare, from a Chinese societal perspective, the projected health benefits, costs, and cost-effectiveness of adding pneumococcal conjugate heptavalent vaccine (PCV-7) to the routine compulsory child immunization schedule. A decision-tree model, with data and assumptions adapted for relevance to China, was developed to project the health outcomes of PCV-7 vaccination (compared with no vaccination) over a 5-year period as well as a lifetime. The vaccinated birth cohort included 16,000,000 children in China. A 2 + 1 dose schedule at US$136.51 per vaccine dose was used in the base-case analysis. One-way sensitivity analysis was used to test the robustness of the model. The impact of a net indirect effect (herd immunity) was evaluated. Outcomes are presented in terms of the saved disease burden, costs, quality-adjusted life years (QALYs) and incremental cost-effectiveness ratio. In a Chinese birth cohort, a PCV-7 vaccination program would reduce the number of pneumococcus-related infections by at least 32% and would prevent 2,682 deaths in the first 5 years of life, saving $1,190 million in total costs and gaining an additional 9,895 QALYs (discounted by 3%). The incremental cost per QALY was estimated to be $530,354. When herd immunity was taken into account, the cost per QALY was estimated to be $95,319. The robustness of the model was influenced mainly by the PCV-7 cost per dose, effectiveness herd immunity and incidence of pneumococcal diseases. With and without herd immunity, the break-even costs in China were $29.05 and $25.87, respectively. Compulsory routine infant vaccination with PCV-7 is projected to substantially reduce pneumococcal disease morbidity, mortality, and related costs in China. However, a universal vaccination program with PCV-7 is not cost-effective at the willingness-to-pay threshold that is currently recommended for China by the World Health Organization.

  3. Localised mixing and heterogeneity in the plankton food web in a frontal region of the Sargasso Sea

    DEFF Research Database (Denmark)

    Richardson, Katherine; Bendtsen, Joøgen; Christensen, Jens Tang

    2014-01-01

    the diatom communities at 10 m and > 100 m (in the deep chlorophyll maximum, DCM) than in other parts of the frontal region. Thorpe displacements supported the hypothesis of elevated mixing intensities around these stations, as did vertical mixing rates inferred from stratification and vertical current shear...... influence the plankton food web, as indicated by elevated values/concentrations of (1) primary production, (2) variable fluorescence (F-v/F-m) and (3) total seston. In addition, the fraction of the total biomass of both copepods and nauplii found closest to the DCM in the frontal region correlated...

  4. Localised mixing and heterogeneity in the plankton food web in a frontal region of the Sargasso Sea

    DEFF Research Database (Denmark)

    Richardson, Katherine; Bendtsen, Joøgen; Christensen, Jens Tang

    2014-01-01

    the diatom communities at 10 m and > 100 m (in the deep chlorophyll maximum, DCM) than in other parts of the frontal region. Thorpe displacements supported the hypothesis of elevated mixing intensities around these stations, as did vertical mixing rates inferred from stratification and vertical current shear...... with the stratification (Brunt-V is l frequency), with the greatest fractions found below 75 m at the most weakly stratified stations. While this study cannot directly link these observations to eel larvae ecology, Munk et al. (2010; Proc R Soc B 277: 3593-3599) reported that eel larvae were most abundant at locations...

  5. Effectiveness of an educative intervention developed on pupils of Compulsory Secondary Education´s first course in Madrid about social gender estereotype

    Directory of Open Access Journals (Sweden)

    Sara Sánchez Castro

    2011-09-01

    Full Text Available Violence against women frequently focus on people who live together, leaving aside violence exert in those couples where individual do not live together, more common in adolescents, and which has been called "dating violence". Adolescents are a poblational group with some specific risk factors, due to, among other things, the fact that their behavior is determinated by a competitive, liberate society, where there is still gender stereotypes, shaped, as Glick and Fiske noticed, by an ambivalent sexism, where stereotypes are not only hostile but also benevolent, but which, anyway, predispose towards violent attitudes both physical and psychological. Numerous studies about these subject show that the way to prevent this kind of violence is acting from education; actually, in the subject Education for citizenship special attention is paid on the women and men equality. Many studies have developed interventions to prevent dating violence through education in gender equality, but these studies have evaluated their intervention developed by the students and teachers valuation, the intervention effectiveness was not really measured. Thus, we think it would be interesting to evaluate, with a validated instrument as the Ambivalent Sexism Inventory for adolescents the effectiveness of an educative intervention focused on reduce the sexist prejudice both hostile and benevolent in a population of pupils who attend to first course of Compulsory Secondary Education. To achieve this, we have developed a group clinical trial where experimental group will attend to four educative sessions focused on reduce sexist prejudice, and the control group will receive the equality formation compulsory in this cycle. Randomization will be realized by centers, so pupils will belong to experimental or control group depending on which center they attend to.

  6. Tradeoffs in Chemical and Thermal Variations in the Post-perovskite Phase Transition: Mixed Phase Regions in the Deep Lower Mantle?

    Science.gov (United States)

    Giles, G. F.; Spera, F. J.; Yuen, D. A.

    2005-12-01

    The recent discovery of a phase-transition in Mg-rich perovskite (Pv) to a post-perovskite (pPv) phase at lower mantle depths and its relationship to D", lower mantle heterogeneity and iron content prompted an investigation of the relative importance of lower mantle (LM) compositional and temperature fluctuations in creating topographic undulations on mixed phase regions. Above the transition, Mg-rich Pv makes up ~70 percent by mass of the LM. Using results from experimental phase equilibria, first-principles computations and thermodynamic relations for Fe2+-Mg mixing in silicates, a preliminary thermodynamic model for the perovskite to post-perovskite phase transition in the divariant system MgSiO3-FeSiO3 is developed. Complexities associated with components Fe2O3 and Al2O3 and other phases (Ca-Pv, magnesiowustite) are neglected. The model predicts phase transition pressures are sensitive to the FeSiO3 content of perovskite (~-1.5 GPa per one mole percent FeSiO3). This leads to considerable topography along the top boundary of the mixed phase region. The Clapeyron slope for the Pv to pPv transition at XFeSiO3=0.1 is +11 MPa/K about 20% higher than for pure Mg-Pv. Increasing bulk concentration of iron elevates the mixed (two-phase) layer above the core-mantle boundary (CMB); increasing temperature acts to push the mixed layer deeper into the LM into the D" thermal boundary layer resting upon the (CMB). For various LM geotherms and CMB temperatures, a single mixed layer of thickness ~300 km lies within the bottom 40% of the lower mantle. For low iron contents (XFeSiO3 ~5 mole percent or less), two perched layers are found. This is the divariant analog to the univariant double-crosser. The hotter the mantle, the deeper the mixed phase layer; the more iron-rich the LM, the higher the mixed phase layer. In a hotter Hadean Earth with interior temperatures everywhere 200-500 K warmer pPv is not stable unless the LM bulk composition is Fe-enriched compared to the present

  7. Deep subsurface microbial processes

    Science.gov (United States)

    Lovley, D.R.; Chapelle, F.H.

    1995-01-01

    Information on the microbiology of the deep subsurface is necessary in order to understand the factors controlling the rate and extent of the microbially catalyzed redox reactions that influence the geophysical properties of these environments. Furthermore, there is an increasing threat that deep aquifers, an important drinking water resource, may be contaminated by man's activities, and there is a need to predict the extent to which microbial activity may remediate such contamination. Metabolically active microorganisms can be recovered from a diversity of deep subsurface environments. The available evidence suggests that these microorganisms are responsible for catalyzing the oxidation of organic matter coupled to a variety of electron acceptors just as microorganisms do in surface sediments, but at much slower rates. The technical difficulties in aseptically sampling deep subsurface sediments and the fact that microbial processes in laboratory incubations of deep subsurface material often do not mimic in situ processes frequently necessitate that microbial activity in the deep subsurface be inferred through nonmicrobiological analyses of ground water. These approaches include measurements of dissolved H2, which can predict the predominant microbially catalyzed redox reactions in aquifers, as well as geochemical and groundwater flow modeling, which can be used to estimate the rates of microbial processes. Microorganisms recovered from the deep subsurface have the potential to affect the fate of toxic organics and inorganic contaminants in groundwater. Microbial activity also greatly influences 1 the chemistry of many pristine groundwaters and contributes to such phenomena as porosity development in carbonate aquifers, accumulation of undesirably high concentrations of dissolved iron, and production of methane and hydrogen sulfide. Although the last decade has seen a dramatic increase in interest in deep subsurface microbiology, in comparison with the study of

  8. DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network.

    Science.gov (United States)

    Katzman, Jared L; Shaham, Uri; Cloninger, Alexander; Bates, Jonathan; Jiang, Tingting; Kluger, Yuval

    2018-02-26

    Medical practitioners use survival models to explore and understand the relationships between patients' covariates (e.g. clinical and genetic features) and the effectiveness of various treatment options. Standard survival models like the linear Cox proportional hazards model require extensive feature engineering or prior medical knowledge to model treatment interaction at an individual level. While nonlinear survival methods, such as neural networks and survival forests, can inherently model these high-level interaction terms, they have yet to be shown as effective treatment recommender systems. We introduce DeepSurv, a Cox proportional hazards deep neural network and state-of-the-art survival method for modeling interactions between a patient's covariates and treatment effectiveness in order to provide personalized treatment recommendations. We perform a number of experiments training DeepSurv on simulated and real survival data. We demonstrate that DeepSurv performs as well as or better than other state-of-the-art survival models and validate that DeepSurv successfully models increasingly complex relationships between a patient's covariates and their risk of failure. We then show how DeepSurv models the relationship between a patient's features and effectiveness of different treatment options to show how DeepSurv can be used to provide individual treatment recommendations. Finally, we train DeepSurv on real clinical studies to demonstrate how it's personalized treatment recommendations would increase the survival time of a set of patients. The predictive and modeling capabilities of DeepSurv will enable medical researchers to use deep neural networks as a tool in their exploration, understanding, and prediction of the effects of a patient's characteristics on their risk of failure.

  9. Pathogenesis of deep endometriosis.

    Science.gov (United States)

    Gordts, Stephan; Koninckx, Philippe; Brosens, Ivo

    2017-12-01

    The pathophysiology of (deep) endometriosis is still unclear. As originally suggested by Cullen, change the definition "deeper than 5 mm" to "adenomyosis externa." With the discovery of the old European literature on uterine bleeding in 5%-10% of the neonates and histologic evidence that the bleeding represents decidual shedding, it is postulated/hypothesized that endometrial stem/progenitor cells, implanted in the pelvic cavity after birth, may be at the origin of adolescent and even the occasionally premenarcheal pelvic endometriosis. Endometriosis in the adolescent is characterized by angiogenic and hemorrhagic peritoneal and ovarian lesions. The development of deep endometriosis at a later age suggests that deep infiltrating endometriosis is a delayed stage of endometriosis. Another hypothesis is that the endometriotic cell has undergone genetic or epigenetic changes and those specific changes determine the development into deep endometriosis. This is compatible with the hereditary aspects, and with the clonality of deep and cystic ovarian endometriosis. It explains the predisposition and an eventual causal effect by dioxin or radiation. Specific genetic/epigenetic changes could explain the various expressions and thus typical, cystic, and deep endometriosis become three different diseases. Subtle lesions are not a disease until epi(genetic) changes occur. A classification should reflect that deep endometriosis is a specific disease. In conclusion the pathophysiology of deep endometriosis remains debated and the mechanisms of disease progression, as well as the role of genetics and epigenetics in the process, still needs to be unraveled. Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  10. DeepSpark: A Spark-Based Distributed Deep Learning Framework for Commodity Clusters

    OpenAIRE

    Kim, Hanjoo; Park, Jaehong; Jang, Jaehee; Yoon, Sungroh

    2016-01-01

    The increasing complexity of deep neural networks (DNNs) has made it challenging to exploit existing large-scale data processing pipelines for handling massive data and parameters involved in DNN training. Distributed computing platforms and GPGPU-based acceleration provide a mainstream solution to this computational challenge. In this paper, we propose DeepSpark, a distributed and parallel deep learning framework that exploits Apache Spark on commodity clusters. To support parallel operation...

  11. DeepPVP: phenotype-based prioritization of causative variants using deep learning

    KAUST Repository

    Boudellioua, Imene; Kulmanov, Maxat; Schofield, Paul N; Gkoutos, Georgios V; Hoehndorf, Robert

    2018-01-01

    phenotype-based methods that use similar features. DeepPVP is freely available at https://github.com/bio-ontology-research-group/phenomenet-vp Conclusions: DeepPVP further improves on existing variant prioritization methods both in terms of speed as well

  12. DeepARG: a deep learning approach for predicting antibiotic resistance genes from metagenomic data.

    Science.gov (United States)

    Arango-Argoty, Gustavo; Garner, Emily; Pruden, Amy; Heath, Lenwood S; Vikesland, Peter; Zhang, Liqing

    2018-02-01

    Growing concerns about increasing rates of antibiotic resistance call for expanded and comprehensive global monitoring. Advancing methods for monitoring of environmental media (e.g., wastewater, agricultural waste, food, and water) is especially needed for identifying potential resources of novel antibiotic resistance genes (ARGs), hot spots for gene exchange, and as pathways for the spread of ARGs and human exposure. Next-generation sequencing now enables direct access and profiling of the total metagenomic DNA pool, where ARGs are typically identified or predicted based on the "best hits" of sequence searches against existing databases. Unfortunately, this approach produces a high rate of false negatives. To address such limitations, we propose here a deep learning approach, taking into account a dissimilarity matrix created using all known categories of ARGs. Two deep learning models, DeepARG-SS and DeepARG-LS, were constructed for short read sequences and full gene length sequences, respectively. Evaluation of the deep learning models over 30 antibiotic resistance categories demonstrates that the DeepARG models can predict ARGs with both high precision (> 0.97) and recall (> 0.90). The models displayed an advantage over the typical best hit approach, yielding consistently lower false negative rates and thus higher overall recall (> 0.9). As more data become available for under-represented ARG categories, the DeepARG models' performance can be expected to be further enhanced due to the nature of the underlying neural networks. Our newly developed ARG database, DeepARG-DB, encompasses ARGs predicted with a high degree of confidence and extensive manual inspection, greatly expanding current ARG repositories. The deep learning models developed here offer more accurate antimicrobial resistance annotation relative to current bioinformatics practice. DeepARG does not require strict cutoffs, which enables identification of a much broader diversity of ARGs. The

  13. Stimulation Technologies for Deep Well Completions

    Energy Technology Data Exchange (ETDEWEB)

    None

    2003-09-30

    The Department of Energy (DOE) is sponsoring the Deep Trek Program targeted at improving the economics of drilling and completing deep gas wells. Under the DOE program, Pinnacle Technologies is conducting a study to evaluate the stimulation of deep wells. The objective of the project is to assess U.S. deep well drilling & stimulation activity, review rock mechanics & fracture growth in deep, high pressure/temperature wells and evaluate stimulation technology in several key deep plays. An assessment of historical deep gas well drilling activity and forecast of future trends was completed during the first six months of the project; this segment of the project was covered in Technical Project Report No. 1. The second progress report covers the next six months of the project during which efforts were primarily split between summarizing rock mechanics and fracture growth in deep reservoirs and contacting operators about case studies of deep gas well stimulation.

  14. DeepQA: improving the estimation of single protein model quality with deep belief networks.

    Science.gov (United States)

    Cao, Renzhi; Bhattacharya, Debswapna; Hou, Jie; Cheng, Jianlin

    2016-12-05

    Protein quality assessment (QA) useful for ranking and selecting protein models has long been viewed as one of the major challenges for protein tertiary structure prediction. Especially, estimating the quality of a single protein model, which is important for selecting a few good models out of a large model pool consisting of mostly low-quality models, is still a largely unsolved problem. We introduce a novel single-model quality assessment method DeepQA based on deep belief network that utilizes a number of selected features describing the quality of a model from different perspectives, such as energy, physio-chemical characteristics, and structural information. The deep belief network is trained on several large datasets consisting of models from the Critical Assessment of Protein Structure Prediction (CASP) experiments, several publicly available datasets, and models generated by our in-house ab initio method. Our experiments demonstrate that deep belief network has better performance compared to Support Vector Machines and Neural Networks on the protein model quality assessment problem, and our method DeepQA achieves the state-of-the-art performance on CASP11 dataset. It also outperformed two well-established methods in selecting good outlier models from a large set of models of mostly low quality generated by ab initio modeling methods. DeepQA is a useful deep learning tool for protein single model quality assessment and protein structure prediction. The source code, executable, document and training/test datasets of DeepQA for Linux is freely available to non-commercial users at http://cactus.rnet.missouri.edu/DeepQA/ .

  15. Magma Mixing: Why Picrites are Not So Hot

    Science.gov (United States)

    Natland, J. H.

    2010-12-01

    porosity in regions where crustal-level magma chambers and flanking rift zones do not have a chance to form. Low-magma supply is favored. In the ocean basins, such upper mantle mainlining occurs only at certain fracture zones, deep propagating rifts at microplates, or ultra-slow spreading ridges, but no liquids (glasses) with >10% MgO occur at any of these places. On continents, rift structures through cratons might allow this, but so far no picrite, ferropicrite, or meimichite that has been adequately described from these places lacks evidence for end-member mixing. Low-temperature iron-rich magmas can accumulate in the deep lower crust and later rise to form substantial intrusions (e.g. Skaergaard) or erupt as flood basalts (Columbia River). Some komatiites might represent high-temperature liquids, but many are so altered that original liquid compositions cannot be deduced (e.g., Gorgona). The hottest intraplate volcano is Kilauea, Hawaii, where rare picrite glass with 15% MgO has an estimated eruptive temperature (1) of ~1350C and a potential temperature at 1 GPa of ~1420C. Lavas at all other linear island chains, Iceland and even west Greenland where picrites are abundant, are cooler than this. (1) Beattie, P., 1993. CMP 115: 103-111.

  16. A case of mixed type laryngocele presented with deep neck infection and review of the literature

    Directory of Open Access Journals (Sweden)

    Salih Bakır

    2012-09-01

    Full Text Available Laryngocele is an abnormal dilatation of the laryngeal ventricular saccule that may extend into the subcutaneous tissues of the neck through the thyrohyoid membrane or confined to the endolarynx. The etiology is still unclear. Many laryngoceles are asymptomatic. An asymptomatic laryngocele appears and produces symptoms only as it enlarges or when it becomes infected. In this report, we present a 40-year-old female patient, which had an asymptomatic neck swelling for 20 years, referred for deep neck infection, dysphonia and dyspnea. J Clin Exp Invest 2012; 3 (3: 415-419Key words: Larynx, laryngocele, laryngopyocele, neck mass

  17. Stimulation Technologies for Deep Well Completions

    Energy Technology Data Exchange (ETDEWEB)

    Stephen Wolhart

    2005-06-30

    The Department of Energy (DOE) is sponsoring the Deep Trek Program targeted at improving the economics of drilling and completing deep gas wells. Under the DOE program, Pinnacle Technologies conducted a study to evaluate the stimulation of deep wells. The objective of the project was to review U.S. deep well drilling and stimulation activity, review rock mechanics and fracture growth in deep, high-pressure/temperature wells and evaluate stimulation technology in several key deep plays. This report documents results from this project.

  18. DeepPicker: A deep learning approach for fully automated particle picking in cryo-EM.

    Science.gov (United States)

    Wang, Feng; Gong, Huichao; Liu, Gaochao; Li, Meijing; Yan, Chuangye; Xia, Tian; Li, Xueming; Zeng, Jianyang

    2016-09-01

    Particle picking is a time-consuming step in single-particle analysis and often requires significant interventions from users, which has become a bottleneck for future automated electron cryo-microscopy (cryo-EM). Here we report a deep learning framework, called DeepPicker, to address this problem and fill the current gaps toward a fully automated cryo-EM pipeline. DeepPicker employs a novel cross-molecule training strategy to capture common features of particles from previously-analyzed micrographs, and thus does not require any human intervention during particle picking. Tests on the recently-published cryo-EM data of three complexes have demonstrated that our deep learning based scheme can successfully accomplish the human-level particle picking process and identify a sufficient number of particles that are comparable to those picked manually by human experts. These results indicate that DeepPicker can provide a practically useful tool to significantly reduce the time and manual effort spent in single-particle analysis and thus greatly facilitate high-resolution cryo-EM structure determination. DeepPicker is released as an open-source program, which can be downloaded from https://github.com/nejyeah/DeepPicker-python. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. DeepBase: annotation and discovery of microRNAs and other noncoding RNAs from deep-sequencing data.

    Science.gov (United States)

    Yang, Jian-Hua; Qu, Liang-Hu

    2012-01-01

    Recent advances in high-throughput deep-sequencing technology have produced large numbers of short and long RNA sequences and enabled the detection and profiling of known and novel microRNAs (miRNAs) and other noncoding RNAs (ncRNAs) at unprecedented sensitivity and depth. In this chapter, we describe the use of deepBase, a database that we have developed to integrate all public deep-sequencing data and to facilitate the comprehensive annotation and discovery of miRNAs and other ncRNAs from these data. deepBase provides an integrative, interactive, and versatile web graphical interface to evaluate miRBase-annotated miRNA genes and other known ncRNAs, explores the expression patterns of miRNAs and other ncRNAs, and discovers novel miRNAs and other ncRNAs from deep-sequencing data. deepBase also provides a deepView genome browser to comparatively analyze these data at multiple levels. deepBase is available at http://deepbase.sysu.edu.cn/.

  20. Deep Borehole Disposal as an Alternative Concept to Deep Geological Disposal

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jongyoul; Lee, Minsoo; Choi, Heuijoo; Kim, Kyungsu [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    In this paper, the general concept and key technologies for deep borehole disposal of spent fuels or HLW, as an alternative method to the mined geological disposal method, were reviewed. After then an analysis on the distance between boreholes for the disposal of HLW was carried out. Based on the results, a disposal area were calculated approximately and compared with that of mined geological disposal. These results will be used as an input for the analyses of applicability for DBD in Korea. The disposal safety of this system has been demonstrated with underground research laboratory and some advanced countries such as Finland and Sweden are implementing their disposal project on commercial stage. However, if the spent fuels or the high-level radioactive wastes can be disposed of in the depth of 3-5 km and more stable rock formation, it has several advantages. Therefore, as an alternative disposal concept to the mined deep geological disposal concept (DGD), very deep borehole disposal (DBD) technology is under consideration in number of countries in terms of its outstanding safety and cost effectiveness. In this paper, the general concept of deep borehole disposal for spent fuels or high level radioactive wastes was reviewed. And the key technologies, such as drilling technology of large diameter borehole, packaging and emplacement technology, sealing technology and performance/safety analyses technologies, and their challenges in development of deep borehole disposal system were analyzed. Also, very preliminary deep borehole disposal concept including disposal canister concept was developed according to the nuclear environment in Korea.

  1. Deep Borehole Disposal as an Alternative Concept to Deep Geological Disposal

    International Nuclear Information System (INIS)

    Lee, Jongyoul; Lee, Minsoo; Choi, Heuijoo; Kim, Kyungsu

    2016-01-01

    In this paper, the general concept and key technologies for deep borehole disposal of spent fuels or HLW, as an alternative method to the mined geological disposal method, were reviewed. After then an analysis on the distance between boreholes for the disposal of HLW was carried out. Based on the results, a disposal area were calculated approximately and compared with that of mined geological disposal. These results will be used as an input for the analyses of applicability for DBD in Korea. The disposal safety of this system has been demonstrated with underground research laboratory and some advanced countries such as Finland and Sweden are implementing their disposal project on commercial stage. However, if the spent fuels or the high-level radioactive wastes can be disposed of in the depth of 3-5 km and more stable rock formation, it has several advantages. Therefore, as an alternative disposal concept to the mined deep geological disposal concept (DGD), very deep borehole disposal (DBD) technology is under consideration in number of countries in terms of its outstanding safety and cost effectiveness. In this paper, the general concept of deep borehole disposal for spent fuels or high level radioactive wastes was reviewed. And the key technologies, such as drilling technology of large diameter borehole, packaging and emplacement technology, sealing technology and performance/safety analyses technologies, and their challenges in development of deep borehole disposal system were analyzed. Also, very preliminary deep borehole disposal concept including disposal canister concept was developed according to the nuclear environment in Korea

  2. Mixing and Progressive Melting of Deep and Shallow Mantle Sources in the NE Atlantic and Arctic

    DEFF Research Database (Denmark)

    Trønnes, Reidar; Debaille, Vincianne; Erambert, M.

    2013-01-01

    ). The SCLM-component was mixed with the local asthenosphere during and shortly after the continental rifting and ocean basin opening. Using combined Sr-Nd-Pb- Os-He-isotope systematics, the Iceland plume can be modelled as a mixture of 70% refractory/primordial lower mantle (LM) and 30% recycled oceanic...

  3. Is the Right of Children to Free and Compulsory Education Act Really Beneficial to the Poorer Children in India? An Analysis with Special Reference to the Admission of Poorer Children in Public Unaided Schools

    Science.gov (United States)

    Cheruvalath, Reena

    2015-01-01

    It is proposed to examine whether the Right of Children to Free and Compulsory Education Act can achieve its major objective of ensuring education for all children in India. Indian parents like to enter their wards into private schools because they believe that the standard of education in the public schools is poor. The act strengthens this…

  4. Evaluation of vertical coordinate and vertical mixing algorithms in the HYbrid-Coordinate Ocean Model (HYCOM)

    Science.gov (United States)

    Halliwell, George R.

    Vertical coordinate and vertical mixing algorithms included in the HYbrid Coordinate Ocean Model (HYCOM) are evaluated in low-resolution climatological simulations of the Atlantic Ocean. The hybrid vertical coordinates are isopycnic in the deep ocean interior, but smoothly transition to level (pressure) coordinates near the ocean surface, to sigma coordinates in shallow water regions, and back again to level coordinates in very shallow water. By comparing simulations to climatology, the best model performance is realized using hybrid coordinates in conjunction with one of the three available differential vertical mixing models: the nonlocal K-Profile Parameterization, the NASA GISS level 2 turbulence closure, and the Mellor-Yamada level 2.5 turbulence closure. Good performance is also achieved using the quasi-slab Price-Weller-Pinkel dynamical instability model. Differences among these simulations are too small relative to other errors and biases to identify the "best" vertical mixing model for low-resolution climate simulations. Model performance deteriorates slightly when the Kraus-Turner slab mixed layer model is used with hybrid coordinates. This deterioration is smallest when solar radiation penetrates beneath the mixed layer and when shear instability mixing is included. A simulation performed using isopycnic coordinates to emulate the Miami Isopycnic Coordinate Ocean Model (MICOM), which uses Kraus-Turner mixing without penetrating shortwave radiation and shear instability mixing, demonstrates that the advantages of switching from isopycnic to hybrid coordinates and including more sophisticated turbulence closures outweigh the negative numerical effects of maintaining hybrid vertical coordinates.

  5. Deep Mapping and Spatial Anthropology

    Directory of Open Access Journals (Sweden)

    Les Roberts

    2016-01-01

    Full Text Available This paper provides an introduction to the Humanities Special Issue on “Deep Mapping”. It sets out the rationale for the collection and explores the broad-ranging nature of perspectives and practices that fall within the “undisciplined” interdisciplinary domain of spatial humanities. Sketching a cross-current of ideas that have begun to coalesce around the concept of “deep mapping”, the paper argues that rather than attempting to outline a set of defining characteristics and “deep” cartographic features, a more instructive approach is to pay closer attention to the multivalent ways deep mapping is performatively put to work. Casting a critical and reflexive gaze over the developing discourse of deep mapping, it is argued that what deep mapping “is” cannot be reduced to the otherwise a-spatial and a-temporal fixity of the “deep map”. In this respect, as an undisciplined survey of this increasing expansive field of study and practice, the paper explores the ways in which deep mapping can engage broader discussion around questions of spatial anthropology.

  6. Deep Vein Thrombosis

    African Journals Online (AJOL)

    OWNER

    Deep Vein Thrombosis: Risk Factors and Prevention in Surgical Patients. Deep Vein ... preventable morbidity and mortality in hospitalized surgical patients. ... the elderly.3,4 It is very rare before the age ... depends on the risk level; therefore an .... but also in the post-operative period. ... is continuing uncertainty regarding.

  7. Southern Ocean Circulation: a High Resolution Examination of the Last Deglaciation from Deep-Sea Corals

    Science.gov (United States)

    Robinson, L. F.; Li, T.; Chen, T.; Burke, A.; Pegrum Haram, A.; Stewart, J.; Rae, J. W. B.; van de Flierdt, T.; Struve, T.; Wilson, D. J.

    2017-12-01

    Two decades ago it was first noted that the skeletal remains of deep-sea corals had the potential to provide absolutely dated archives of past ocean conditions. In the intervening twenty years this field has developed to the point where strategic collections and high throughput dating techniques now allow high resolution, well dated records of past deep sea behaviour to be produced. Likewise, efforts to improve understanding of biomineralisation and growth rates are leading to refinements in proxy tools useful for examining circulation, nutrient and carbon cycling, temperature and weathering processes. Deep-sea corals are particularly valuable archives in high latitude regions where radiocarbon-based age models are susceptible to large changes in surface reservoir ages. In this presentation we show new high resolution multiproxy records of the Southern Ocean (Drake Passage) made on U-Th dated corals spanning the last glacial cycle. With more than seventeen hundred reconnaissance ages, and around 200 precise isotope dilution U-Th ages, subtle changes in ocean behaviour can be identified during times of abrupt climate change. The geochemical signature of corals from the deepest sites, closest to modern day Lower Circumpolar Deep Waters, typically show a gradual shift from glacial to Holocene values during deglaciation, likely related to ventilation of the deep ocean. By contrast for the samples collected shallower in the water column (within sites currently bathed by Upper Circumpolar Deep Waters and Antarctic Intermediate and Mode Waters) the evidence points to a more complicated picture. Vertical zonation in the geochemical data suggests that periods of stratification are interspersed with mixing events within the upper 1500m of the water column. At the same time comparison to U-Th dated records from the low latitude Pacific and Atlantic points to an important role for the Southern Ocean in feeding the intermediate waters of both ocean basins throughout the

  8. Mixing ratio sensor of alcohol mixed fuel

    Energy Technology Data Exchange (ETDEWEB)

    Miyata, Shigeru; Matsubara, Yoshihiro

    1987-08-07

    In order to improve combustion efficiency of an internal combustion engine using gasoline-alcohol mixed fuel and to reduce harmful substance in its exhaust gas, it is necessary to control strictly the air-fuel ratio to be supplied and the ignition timing and change the condition of control depending upon the mixing ratio of the mixed fuel. In order to detect the mixing ratio of the mixed fuel, the above mixing ratio has so far been detected by casting a ray of light to the mixed fuel and utilizing a change of critical angle associated with the change of the composition of the fluid of the mixed fuel. However, in case when a light emitting diode is used for the light source above, two kinds of sensors are further needed. Concerning the two kinds of sensors above, this invention offers a mixing ratio sensor for the alcohol mixed fuel which can abolish a temperature sensor to detect the environmental temperature by making a single compensatory light receiving element deal with the compensation of the amount of light emission of the light emitting element due to the temperature change and the compensation of the critical angle caused by the temperature change. (6 figs)

  9. pDeep: Predicting MS/MS Spectra of Peptides with Deep Learning.

    Science.gov (United States)

    Zhou, Xie-Xuan; Zeng, Wen-Feng; Chi, Hao; Luo, Chunjie; Liu, Chao; Zhan, Jianfeng; He, Si-Min; Zhang, Zhifei

    2017-12-05

    In tandem mass spectrometry (MS/MS)-based proteomics, search engines rely on comparison between an experimental MS/MS spectrum and the theoretical spectra of the candidate peptides. Hence, accurate prediction of the theoretical spectra of peptides appears to be particularly important. Here, we present pDeep, a deep neural network-based model for the spectrum prediction of peptides. Using the bidirectional long short-term memory (BiLSTM), pDeep can predict higher-energy collisional dissociation, electron-transfer dissociation, and electron-transfer and higher-energy collision dissociation MS/MS spectra of peptides with >0.9 median Pearson correlation coefficients. Further, we showed that intermediate layer of the neural network could reveal physicochemical properties of amino acids, for example the similarities of fragmentation behaviors between amino acids. We also showed the potential of pDeep to distinguish extremely similar peptides (peptides that contain isobaric amino acids, for example, GG = N, AG = Q, or even I = L), which were very difficult to distinguish using traditional search engines.

  10. Genomic variation in macrophage-cultured European porcine reproductive and respiratory syndrome virus Olot/91 revealed using ultra-deep next generation sequencing.

    Science.gov (United States)

    Lu, Zen H; Brown, Alexander; Wilson, Alison D; Calvert, Jay G; Balasch, Monica; Fuentes-Utrilla, Pablo; Loecherbach, Julia; Turner, Frances; Talbot, Richard; Archibald, Alan L; Ait-Ali, Tahar

    2014-03-04

    Porcine Reproductive and Respiratory Syndrome (PRRS) is a disease of major economic impact worldwide. The etiologic agent of this disease is the PRRS virus (PRRSV). Increasing evidence suggest that microevolution within a coexisting quasispecies population can give rise to high sequence heterogeneity in PRRSV. We developed a pipeline based on the ultra-deep next generation sequencing approach to first construct the complete genome of a European PRRSV, strain Olot/9, cultured on macrophages and then capture the rare variants representative of the mixed quasispecies population. Olot/91 differs from the reference Lelystad strain by about 5% and a total of 88 variants, with frequencies as low as 1%, were detected in the mixed population. These variants included 16 non-synonymous variants concentrated in the genes encoding structural and nonstructural proteins; including Glycoprotein 2a and 5. Using an ultra-deep sequencing methodology, the complete genome of Olot/91 was constructed without any prior knowledge of the sequence. Rare variants that constitute minor fractions of the heterogeneous PRRSV population could successfully be detected to allow further exploration of microevolutionary events.

  11. A Tale Of Two States: Mississippi, West Virginia, And Exemptions To Compulsory School Vaccination Laws.

    Science.gov (United States)

    Colgrove, James; Lowin, Abigail

    2016-02-01

    School-based compulsory vaccination laws have provoked debates over the legitimacy of government coercion versus the scope of parental rights. A key point of contention in these school vaccination laws are provisions known as exemption clauses that allow some parents to enroll their children in school unimmunized for reasons other than medical conditions. For more than three decades Mississippi and West Virginia stood apart as the only two US states that did not offer nonmedical exemptions to school vaccination laws. But other states seem to be moving in this direction, such as California, which in 2015 eliminated nonmedical exemptions following the Disneyland measles outbreak. The apparent shift creates an opportune moment to look at the experiences of Mississippi and West Virginia. Through a review of legislative histories, legal rulings, media accounts, and interviews with health officials in the two states, we consider the reasons for and consequences of their allowing only medical exemptions and the prospects their approach holds out for other states that may wish to emulate it. The experiences of these two states suggest that contrary to conventional wisdom, it may be politically tenable to limit exemptions to only medical reasons without damaging either the stature of public health or the immunization system. Project HOPE—The People-to-People Health Foundation, Inc.

  12. Controls on turbulent mixing on the West Antarctic Peninsula shelf

    Science.gov (United States)

    Brearley, J. Alexander; Meredith, Michael P.; Naveira Garabato, Alberto C.; Venables, Hugh J.; Inall, Mark E.

    2017-05-01

    The ocean-to-atmosphere heat budget of the West Antarctic Peninsula is controlled in part by the upward flux of heat from the warm Circumpolar Deep Water (CDW) layer that resides below 200 m to the Antarctic Surface Water (AASW), a water mass which varies strongly on a seasonal basis. Upwelling and mixing of CDW influence the formation of sea ice in the region and affect biological productivity and functioning of the ecosystem through their delivery of nutrients. In this study, 2.5-year time series of both Acoustic Doppler Current Profiler (ADCP) and conductivity-temperature-depth (CTD) data are used to quantify both the diapycnal diffusivity κ and the vertical heat flux Q at the interface between CDW and AASW. Over the period of the study, a mean upward heat flux of 1 W m-2 is estimated, with the largest heat fluxes occurring shortly after the loss of winter fast ice when the water column is first exposed to wind stress without being strongly stratified by salinity. Differences in mixing mechanisms between winter and summer seasons are investigated. Whilst tidally-driven mixing at the study site occurs year-round, but is likely to be relatively weak, a strong increase in counterclockwise-polarized near-inertial energy (and shear) is observed during the fast-ice-free season, suggesting that the direct impact of storms on the ocean surface is responsible for much of the observed mixing at the site. Given the rapid reduction in sea-ice duration in this region in the last 30 years, a shift towards an increasingly wind-dominated mixing regime may be taking place.

  13. Mixed deep learning and natural language processing method for fake-food image recognition and standardization to help automated dietary assessment.

    Science.gov (United States)

    Mezgec, Simon; Eftimov, Tome; Bucher, Tamara; Koroušić Seljak, Barbara

    2018-04-06

    The present study tested the combination of an established and a validated food-choice research method (the 'fake food buffet') with a new food-matching technology to automate the data collection and analysis. The methodology combines fake-food image recognition using deep learning and food matching and standardization based on natural language processing. The former is specific because it uses a single deep learning network to perform both the segmentation and the classification at the pixel level of the image. To assess its performance, measures based on the standard pixel accuracy and Intersection over Union were applied. Food matching firstly describes each of the recognized food items in the image and then matches the food items with their compositional data, considering both their food names and their descriptors. The final accuracy of the deep learning model trained on fake-food images acquired by 124 study participants and providing fifty-five food classes was 92·18 %, while the food matching was performed with a classification accuracy of 93 %. The present findings are a step towards automating dietary assessment and food-choice research. The methodology outperforms other approaches in pixel accuracy, and since it is the first automatic solution for recognizing the images of fake foods, the results could be used as a baseline for possible future studies. As the approach enables a semi-automatic description of recognized food items (e.g. with respect to FoodEx2), these can be linked to any food composition database that applies the same classification and description system.

  14. Enhanced removal of lead from contaminated soil by polyol-based deep eutectic solvents and saponin

    Science.gov (United States)

    Mukhopadhyay, Soumyadeep; Mukherjee, Sumona; Hayyan, Adeeb; Hayyan, Maan; Hashim, Mohd Ali; Sen Gupta, Bhaskar

    2016-11-01

    Deep eutectic solvents (DESs) are a class of green solvents analogous to ionic liquids, but less costly and easier to prepare. The objective of this study is to remove lead (Pb) from a contaminated soil by using polyol based DESs mixed with a natural surfactant saponin for the first time. The DESs used in this study were prepared by mixing a quaternary ammonium salt choline chloride with polyols e.g. glycerol and ethylene glycol. A natural surfactant saponin obtained from soapnut fruit pericarp, was mixed with DESs to boost their efficiency. The DESs on their own did not perform satisfactory due to higher pH; however, they improved the performance of soapnut by up to 100%. Pb removal from contaminated soil using mixture of 40% DES-Gly and 1% saponin and mixture of 10% DES-Gly and 2% saponin were above 72% XRD and SEM studies did not detect any major corrosion in the soil texture. The environmental friendliness of both DESs and saponin and their affordable costs merit thorough investigation of their potential as soil washing agents.

  15. Searching for prostate cancer by fully automated magnetic resonance imaging classification: deep learning versus non-deep learning.

    Science.gov (United States)

    Wang, Xinggang; Yang, Wei; Weinreb, Jeffrey; Han, Juan; Li, Qiubai; Kong, Xiangchuang; Yan, Yongluan; Ke, Zan; Luo, Bo; Liu, Tao; Wang, Liang

    2017-11-13

    Prostate cancer (PCa) is a major cause of death since ancient time documented in Egyptian Ptolemaic mummy imaging. PCa detection is critical to personalized medicine and varies considerably under an MRI scan. 172 patients with 2,602 morphologic images (axial 2D T2-weighted imaging) of the prostate were obtained. A deep learning with deep convolutional neural network (DCNN) and a non-deep learning with SIFT image feature and bag-of-word (BoW), a representative method for image recognition and analysis, were used to distinguish pathologically confirmed PCa patients from prostate benign conditions (BCs) patients with prostatitis or prostate benign hyperplasia (BPH). In fully automated detection of PCa patients, deep learning had a statistically higher area under the receiver operating characteristics curve (AUC) than non-deep learning (P = 0.0007 deep learning method and 0.70 (95% CI 0.63-0.77) for non-deep learning method, respectively. Our results suggest that deep learning with DCNN is superior to non-deep learning with SIFT image feature and BoW model for fully automated PCa patients differentiation from prostate BCs patients. Our deep learning method is extensible to image modalities such as MR imaging, CT and PET of other organs.

  16. MIX-MEDIA NARRATIVES WORKSHOP: MULTIDISCIPLINARY TEAMS’ PRODUCTION

    Directory of Open Access Journals (Sweden)

    Sonia Liliana da Silva Vieira

    2017-11-01

    Full Text Available The development of creation and content production teams, regarding design and digital publishing areas, their processes and transdisciplinary knowledge, are making deep changes in media production structures, and in its own professional sustainability model. The Mix-media Narratives Workshop that took place at Universidade da Beira Interior (Portugal intended to simulate the reality of production structures and the recent integrated digital writing paradigm, as well as to evaluate the several multi and transdisciplinary challenges that may be present in the creation of digital media contents. Design, journalism and film production students were not only confronted with real editorial development situations, but also with professional feedback, which was possible due to a partnership with the newspaper Expresso.pt. A fellow editor from this newspaper kept track of the sessions, with the help and presence of professors from many of the courses involved. Data gathered from observation notes, pictures and video during laboratorial work meetings, was compiled and crossed with research results, analyses and comments made by the participant professors and Expresso. pt editor’s observations. Our goal was to analyze in which way future workers will deal with the challenging task of collaborating with multidisciplinary teams and produce mix-media content with real publishing purpose.

  17. Deep learning for computational chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Goh, Garrett B. [Advanced Computing, Mathematics, and Data Division, Pacific Northwest National Laboratory, 902 Battelle Blvd Richland Washington 99354; Hodas, Nathan O. [Advanced Computing, Mathematics, and Data Division, Pacific Northwest National Laboratory, 902 Battelle Blvd Richland Washington 99354; Vishnu, Abhinav [Advanced Computing, Mathematics, and Data Division, Pacific Northwest National Laboratory, 902 Battelle Blvd Richland Washington 99354

    2017-03-08

    The rise and fall of artificial neural networks is well documented in the scientific literature of both the fields of computer science and computational chemistry. Yet almost two decades later, we are now seeing a resurgence of interest in deep learning, a machine learning algorithm based on “deep” neural networks. Within the last few years, we have seen the transformative impact of deep learning the computer science domain, notably in speech recognition and computer vision, to the extent that the majority of practitioners in those field are now regularly eschewing prior established models in favor of deep learning models. In this review, we provide an introductory overview into the theory of deep neural networks and their unique properties as compared to traditional machine learning algorithms used in cheminformatics. By providing an overview of the variety of emerging applications of deep neural networks, we highlight its ubiquity and broad applicability to a wide range of challenges in the field, including QSAR, virtual screening, protein structure modeling, QM calculations, materials synthesis and property prediction. In reviewing the performance of deep neural networks, we observed a consistent outperformance against non neural networks state-of-the-art models across disparate research topics, and deep neural network based models often exceeded the “glass ceiling” expectations of their respective tasks. Coupled with the maturity of GPU-accelerated computing for training deep neural networks and the exponential growth of chemical data on which to train these networks on, we anticipate that deep learning algorithms will be a useful tool and may grow into a pivotal role for various challenges in the computational chemistry field.

  18. Deep learning for computational chemistry.

    Science.gov (United States)

    Goh, Garrett B; Hodas, Nathan O; Vishnu, Abhinav

    2017-06-15

    The rise and fall of artificial neural networks is well documented in the scientific literature of both computer science and computational chemistry. Yet almost two decades later, we are now seeing a resurgence of interest in deep learning, a machine learning algorithm based on multilayer neural networks. Within the last few years, we have seen the transformative impact of deep learning in many domains, particularly in speech recognition and computer vision, to the extent that the majority of expert practitioners in those field are now regularly eschewing prior established models in favor of deep learning models. In this review, we provide an introductory overview into the theory of deep neural networks and their unique properties that distinguish them from traditional machine learning algorithms used in cheminformatics. By providing an overview of the variety of emerging applications of deep neural networks, we highlight its ubiquity and broad applicability to a wide range of challenges in the field, including quantitative structure activity relationship, virtual screening, protein structure prediction, quantum chemistry, materials design, and property prediction. In reviewing the performance of deep neural networks, we observed a consistent outperformance against non-neural networks state-of-the-art models across disparate research topics, and deep neural network-based models often exceeded the "glass ceiling" expectations of their respective tasks. Coupled with the maturity of GPU-accelerated computing for training deep neural networks and the exponential growth of chemical data on which to train these networks on, we anticipate that deep learning algorithms will be a valuable tool for computational chemistry. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  19. What Really is Deep Learning Doing?

    OpenAIRE

    Xiong, Chuyu

    2017-01-01

    Deep learning has achieved a great success in many areas, from computer vision to natural language processing, to game playing, and much more. Yet, what deep learning is really doing is still an open question. There are a lot of works in this direction. For example, [5] tried to explain deep learning by group renormalization, and [6] tried to explain deep learning from the view of functional approximation. In order to address this very crucial question, here we see deep learning from perspect...

  20. Taoism and Deep Ecology.

    Science.gov (United States)

    Sylvan, Richard; Bennett, David

    1988-01-01

    Contrasted are the philosophies of Deep Ecology and ancient Chinese. Discusses the cosmology, morality, lifestyle, views of power, politics, and environmental philosophies of each. Concludes that Deep Ecology could gain much from Taoism. (CW)

  1. deepTools2: a next generation web server for deep-sequencing data analysis.

    Science.gov (United States)

    Ramírez, Fidel; Ryan, Devon P; Grüning, Björn; Bhardwaj, Vivek; Kilpert, Fabian; Richter, Andreas S; Heyne, Steffen; Dündar, Friederike; Manke, Thomas

    2016-07-08

    We present an update to our Galaxy-based web server for processing and visualizing deeply sequenced data. Its core tool set, deepTools, allows users to perform complete bioinformatic workflows ranging from quality controls and normalizations of aligned reads to integrative analyses, including clustering and visualization approaches. Since we first described our deepTools Galaxy server in 2014, we have implemented new solutions for many requests from the community and our users. Here, we introduce significant enhancements and new tools to further improve data visualization and interpretation. deepTools continue to be open to all users and freely available as a web service at deeptools.ie-freiburg.mpg.de The new deepTools2 suite can be easily deployed within any Galaxy framework via the toolshed repository, and we also provide source code for command line usage under Linux and Mac OS X. A public and documented API for access to deepTools functionality is also available. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  2. Analysis of Performance Differences among Students in Urban and Non-urban Centers Based on Compulsory Secondary Education Special Awards

    Directory of Open Access Journals (Sweden)

    Rocío Chao-Fernández

    2015-09-01

    Full Text Available This research analyzes how the teaching-learning contexts (urban and non-urban of four provinces and their different towns influence the school performance of Galician students who apply for the compulsory secondary education (ESO, in Spanish special award. The sample is of 1,212 students who have finished the 4th level of ESO with an average score greater than or equal to 9 between 2008 and 2012. For such purpose, we made a comparative analysis using independent samples with Levene’s test through the SPSS V. 22.0.0.0 statistical package. The results indicate that, out of the 12 scores (Galician, Spanish, foreign language, Mathematics and Social Sciences, Geography and History and a test to choose from different options (Physics and Chemistry, Biology and Geology, Latin, Music, Technology and Arts, students from urban schools get better results in 10 of them (83.33%, with significant differences in 6 subjects.

  3. Into the deep: A coarse-grained carbonate turbidite thalweg generated by gigantic submarine chutes

    Science.gov (United States)

    Mulder, Thierry; Gillet, Hervé; Reijmer, John; Droxler, André; cavailhes, Thibault; Hanquiez, Vincent; Fauquembergue, Kelly; Bujan, Stéphane; Blanck, David; bashah, Sara; Guiastrennec, Léa; Fabregas, Natacha; Recouvreur, Audrey; Seibert, Chloé

    2017-04-01

    New high-resolution multibeam mapping, in the Southeastern Bahamas, images in exquisite details the southern part of Exuma Sound, and its unchartered transition area to the deep abyssal plain of the Western North Atlantic bounded by the Bahama Escarpment (BE) between San Salvador Island and Samana Cay, referred here to the San Salvador abyssal plain. The transition area is locally referred to as Crooked Island Passage, loosely delineated by Crooked, Long, and Conception Islands, Rum and Samana Cays. Surprisingly in such a pure carbonate landscape, the newly established map reveals the detailed and complex morphology of a giant valley formed by numerous gravity flows originated in Exuma Sound itself, in addition to many secondary slope gullies and smaller tributaries draining the surrounding upper slopes. The valley referred here as the Exuma canyon system starts with a perched valley with low sinuosity, characterized by several flow restrictions and knickpoints initiated by the presence of drowned isolated platforms and merging tributaries. The valley abruptly transforms itself into a deep incised canyon, rivaling the depth of the Colorado Grand Canyon, through two major knickpoints with outsized chutes exceeding several hundred of meters in height, a total of 1600-1800 m. The sudden transformation of the wide valley into a deep narrow canyon, occurring when the flows incised deep into an underlying lower Cretaceous drowned carbonate platform, generates a huge hydraulic jump and creates an enormous plunge pool and related deposits with mechanisms comparable to the ones operating along giant subaerial waterfalls. The high kinetic flow energy, constrained by this narrow and deeply incised canyon, formed, when it is released at its mouth in the abyssal plain, a wide deep-sea channel with well-developed levees and fan, made of coarse-grained carbonate defined layers separated by fine carbonate sediments mixed with fine siliciclastics transported along the BE by the

  4. WHATS-3: An improved flow-through multi-bottle fluid sampler for deep-sea geofluid research

    Science.gov (United States)

    Miyazaki, Junichi; Makabe, Akiko; Matsui, Yohei; Ebina, Naoya; Tsutsumi, Saki; Ishibashi, Jun-ichiro; Chen, Chong; Kaneko, Sho; Takai, Ken; Kawagucci, Shinsuke

    2017-06-01

    Deep-sea geofluid systems, such as hydrothermal vents and cold seeps, are key to understanding subseafloor environments of Earth. Fluid chemistry, especially, provides crucial information towards elucidating the physical, chemical and biological processes that occur in these ecosystems. To accurately assess fluid and gas properties of deep-sea geofluids, well-designed pressure-tight fluid samplers are indispensable and as such they are important assets of deep-sea geofluid research. Here, the development of a new flow-through, pressure-tight fluid sampler capable of four independent sampling events (two subsamples for liquid and gas analyses from each) is reported. This new sampler, named WHATS-3, is a new addition to the WHATS-series samplers and a major upgrade from the previous WHATS-2 sampler with improvements in sample number, valve operational time, physical robustness, and ease of maintenance. Routine laboratory-based pressure tests proved that it is suitable for operation up to 35 MPa pressure. Successful field tests of the new sampler were also carried out in five hydrothermal fields, two in Indian Ocean and three in Okinawa Trough (max. depth 3,300 m). Relations of Mg and major ion species demonstrated bimodal mixing trends between a hydrothermal fluid and seawater, confirming the high-quality of fluids sampled. The newly developed WHATS-3 sampler is well-balanced in sampling capability, field usability, and maintenance feasibility, and can serve as one of the best geofluid samplers available at present to conduct efficient research of deep-sea geofluid systems.

  5. Is Multitask Deep Learning Practical for Pharma?

    Science.gov (United States)

    Ramsundar, Bharath; Liu, Bowen; Wu, Zhenqin; Verras, Andreas; Tudor, Matthew; Sheridan, Robert P; Pande, Vijay

    2017-08-28

    Multitask deep learning has emerged as a powerful tool for computational drug discovery. However, despite a number of preliminary studies, multitask deep networks have yet to be widely deployed in the pharmaceutical and biotech industries. This lack of acceptance stems from both software difficulties and lack of understanding of the robustness of multitask deep networks. Our work aims to resolve both of these barriers to adoption. We introduce a high-quality open-source implementation of multitask deep networks as part of the DeepChem open-source platform. Our implementation enables simple python scripts to construct, fit, and evaluate sophisticated deep models. We use our implementation to analyze the performance of multitask deep networks and related deep models on four collections of pharmaceutical data (three of which have not previously been analyzed in the literature). We split these data sets into train/valid/test using time and neighbor splits to test multitask deep learning performance under challenging conditions. Our results demonstrate that multitask deep networks are surprisingly robust and can offer strong improvement over random forests. Our analysis and open-source implementation in DeepChem provide an argument that multitask deep networks are ready for widespread use in commercial drug discovery.

  6. Perceptions of newly-qualified nurses performing compulsory community service in KwaZulu-Natal.

    Science.gov (United States)

    Govender, Selverani; Brysiewicz, Petra; Bhengu, Busisiwe

    2015-07-08

    Compulsory community service (CCS) for nurses commenced in South African January 2008 after it was legislated in the new Nursing Act (Act No. 33 of 2005). Nurses completing their registered nurse programme are registered as community nurse practitioners (CNPs) during the CCS period and make up the largest number of health professionals serving CCS. Whilst health institutions have welcomed CNPs as additional resources for the shortage of nursing staff, no structured guidelines have been provided at a regional level as to how these nurses should be utilised or managed during the CCS year. To date, no large-scale study has been conducted on nurses carrying out CCS in order to generalise the findings. To establish the perceptions of newly-qualified nurses carrying out CCS in KwaZulu-Natal, South Africa. A quantitative survey design was used to obtain data from a randomly selected sample of the 2012 cohort of nurses carrying out CCS in KwaZulu-Natal. CNPs have a positive attitude toward CCS and perceive themselves as being well prepared for the year of community service in terms of knowledge, skills and ability to administer nursing care. They identified positive benefits of the year of community service.The concerns raised were limited orientation and support; and a few CNPs experienced problems of acceptance by the nurses with whom they work. It is recommended that all health institutions who receive CNPs develop structured orientation and support for these nurses in order to promote their development, thereby enhancing their benefit to the communities they serve.

  7. Turbidite Systems in Brazil: From Outcrops to Deep Waters

    Science.gov (United States)

    ´Avila, R. S. F.; Arienti, L. M.; Vesely, F. F.; Santos, S. F.; Voelcker, H. E.

    2012-04-01

    Reliable depositional models depend on careful observation of rocks, to allow the correct description and interpretation of facies and facies associations and their formative processes. They are of paramount importance to characterize deep water depositional systems, which still are the most important siliciclastic reservoirs for the oil industry. Turbidite sandstone reservoirs are responsible for almost 80% of petroleum produced from Brazilian Basins. A comprehensive characterization of these systems, depicting the main differences in terms of their geometries and facies will be presented. In Brazilian basins most of the turbidites were originated from extremely catastrophic flows, essentially linked to fluvio-deltaic influx that generates very dense hyperpycnal flows. Based on outcrop and subsurface data, two main zones with characteristic geometries and facies associations are commonly identified in turbidite systems: the transference zone and the depositional zone. Erosion and bypass dominate in the transference zone, which frequently occur as submarine canyons and channels. Turbidite channels can contain residual conglomeratic facies and coarser sandstone facies. The depositional area comprises lobes that constitute a major exploratory target because of their greater lateral continuity and the concentration of clean reservoirs. Turbidite lobes can be tabular or lenticular deposits associated with channelized bodies. Taking into account outcrop and subsurface data we can distinguish five main turbidite systems: foredeep turbidite systems, prodelta turbidite systems, mixed turbidite systems, meandering channels turbidite systems and channel-levee turbidite systems. In the Brazilian margin, deep water turbidites and other gravity-flow deposits are commonly associated with bottom current deposits, largely in Tertiary strata. Such bottom current deposits, often called contourites, are also important petroleum reservoirs, commonly mistaken as turbidites. Integration

  8. DeepGait: A Learning Deep Convolutional Representation for View-Invariant Gait Recognition Using Joint Bayesian

    Directory of Open Access Journals (Sweden)

    Chao Li

    2017-02-01

    Full Text Available Human gait, as a soft biometric, helps to recognize people through their walking. To further improve the recognition performance, we propose a novel video sensor-based gait representation, DeepGait, using deep convolutional features and introduce Joint Bayesian to model view variance. DeepGait is generated by using a pre-trained “very deep” network “D-Net” (VGG-D without any fine-tuning. For non-view setting, DeepGait outperforms hand-crafted representations (e.g., Gait Energy Image, Frequency-Domain Feature and Gait Flow Image, etc.. Furthermore, for cross-view setting, 256-dimensional DeepGait after PCA significantly outperforms the state-of-the-art methods on the OU-ISR large population (OULP dataset. The OULP dataset, which includes 4007 subjects, makes our result reliable in a statistically reliable way.

  9. Immunosuppressive compounds from a deep water marine sponge, Agelas flabelliformis.

    Science.gov (United States)

    Gunasekera, S P; Cranick, S; Longley, R E

    1989-01-01

    Two immunosuppressive compounds, 4 alpha-methyl-5 alpha-cholest-8-en-3 beta-ol and 4,5-dibromo-2-pyrrolic acid were isolated from a deep water marine sponge, Agelas flabelliformis. Their structures were determined by comparison of their spectral data with those of samples isolated from other organisms. Both compounds were highly active in suppression of the response of murine splenocytes in the two-way mixed lymphocyte reaction (MLR) with little to no demonstrable cytotoxicity at lower doses. In addition, 4,5-dibromo-2-pyrrolic acid suppressed the proliferative response of splenocytes to suboptimal concentrations of the mitogen, concanavalin A (Con A). These results describe for the first time compounds isolated from the marine sponge A. flabelliformis that possess potent in vitro immunosuppressive activity.

  10. Invited talk: Deep Learning Meets Physics

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    Deep Learning has emerged as one of the most successful fields of machine learning and artificial intelligence with overwhelming success in industrial speech, text and vision benchmarks. Consequently it evolved into the central field of research for IT giants like Google, facebook, Microsoft, Baidu, and Amazon. Deep Learning is founded on novel neural network techniques, the recent availability of very fast computers, and massive data sets. In its core, Deep Learning discovers multiple levels of abstract representations of the input. The main obstacle to learning deep neural networks is the vanishing gradient problem. The vanishing gradient impedes credit assignment to the first layers of a deep network or to early elements of a sequence, therefore limits model selection. Major advances in Deep Learning can be related to avoiding the vanishing gradient like stacking, ReLUs, residual networks, highway networks, and LSTM. For Deep Learning, we suggested self-normalizing neural networks (SNNs) which automatica...

  11. Deep geothermics

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    The hot-dry-rocks located at 3-4 km of depth correspond to low permeable rocks carrying a large amount of heat. The extraction of this heat usually requires artificial hydraulic fracturing of the rock to increase its permeability before water injection. Hot-dry-rocks geothermics or deep geothermics is not today a commercial channel but only a scientific and technological research field. The Soultz-sous-Forets site (Northern Alsace, France) is characterized by a 6 degrees per meter geothermal gradient and is used as a natural laboratory for deep geothermal and geological studies in the framework of a European research program. Two boreholes have been drilled up to 3600 m of depth in the highly-fractured granite massif beneath the site. The aim is to create a deep heat exchanger using only the natural fracturing for water transfer. A consortium of german, french and italian industrial companies (Pfalzwerke, Badenwerk, EdF and Enel) has been created for a more active participation to the pilot phase. (J.S.). 1 fig., 2 photos

  12. Stable architectures for deep neural networks

    Science.gov (United States)

    Haber, Eldad; Ruthotto, Lars

    2018-01-01

    Deep neural networks have become invaluable tools for supervised machine learning, e.g. classification of text or images. While often offering superior results over traditional techniques and successfully expressing complicated patterns in data, deep architectures are known to be challenging to design and train such that they generalize well to new data. Critical issues with deep architectures are numerical instabilities in derivative-based learning algorithms commonly called exploding or vanishing gradients. In this paper, we propose new forward propagation techniques inspired by systems of ordinary differential equations (ODE) that overcome this challenge and lead to well-posed learning problems for arbitrarily deep networks. The backbone of our approach is our interpretation of deep learning as a parameter estimation problem of nonlinear dynamical systems. Given this formulation, we analyze stability and well-posedness of deep learning and use this new understanding to develop new network architectures. We relate the exploding and vanishing gradient phenomenon to the stability of the discrete ODE and present several strategies for stabilizing deep learning for very deep networks. While our new architectures restrict the solution space, several numerical experiments show their competitiveness with state-of-the-art networks.

  13. Mixing ratio sensor for alcohol mixed fuel

    Energy Technology Data Exchange (ETDEWEB)

    Miyata, Shigeru; Matsubara, Yoshihiro

    1987-08-24

    In order to improve the combustion efficiency of an internal combustion engine using gasoline-alcohol mixed fuel and to reduce harmful substance in its exhaust gas, it is necessary to control strictly the air-fuel ratio to be supplied and the ignition timing. In order to detect the mixing ratio of the mixed fuel, a mixing ratio sensor has so far been proposed to detect the above mixing ratio by casting a ray of light to the mixed fuel and utilizing a change of critical angle associated with the change of the composition of the fluid of the mixed fuel. However, because of the arrangement of its transparent substance in the fuel passage with the sealing material in between, this sensor invited the leakage of the fluid due to deterioration of the sealing material, etc. and its cost became high because of too many parts to be assembled. In view of the above, in order to reduce the number of parts, to lower the cost of parts and the assembling cost and to secure no fluid leakage from the fuel passage, this invention formed the above fuel passage and the above transparent substance both concerning the above mixing ratio sensor in an integrated manner using light transmitting resin. (3 figs)

  14. Exploring the isopycnal mixing and helium-heat paradoxes in a suite of Earth system models

    Science.gov (United States)

    Gnanadesikan, A.; Pradal, M.-A.; Abernathey, R.

    2015-07-01

    This paper uses a suite of Earth system models which simulate the distribution of He isotopes and radiocarbon to examine two paradoxes in Earth science, each of which results from an inconsistency between theoretically motivated global energy balances and direct observations. The helium-heat paradox refers to the fact that helium emissions to the deep ocean are far lower than would be expected given the rate of geothermal heating, since both are thought to be the result of radioactive decay in Earth's interior. The isopycnal mixing paradox comes from the fact that many theoretical parameterizations of the isopycnal mixing coefficient ARedi that link it to baroclinic instability project it to be small (of order a few hundred m2 s-1) in the ocean interior away from boundary currents. However, direct observations using tracers and floats (largely in the upper ocean) suggest that values of this coefficient are an order of magnitude higher. Helium isotopes equilibrate rapidly with the atmosphere and thus exhibit large gradients along isopycnals while radiocarbon equilibrates slowly and thus exhibits smaller gradients along isopycnals. Thus it might be thought that resolving the isopycnal mixing paradox in favor of the higher observational estimates of ARedi might also solve the helium paradox, by increasing the transport of mantle helium to the surface more than it would radiocarbon. In this paper we show that this is not the case. In a suite of models with different spatially constant and spatially varying values of ARedi the distribution of radiocarbon and helium isotopes is sensitive to the value of ARedi. However, away from strong helium sources in the southeastern Pacific, the relationship between the two is not sensitive, indicating that large-scale advection is the limiting process for removing helium and radiocarbon from the deep ocean. The helium isotopes, in turn, suggest a higher value of ARedi below the thermocline than is seen in theoretical

  15. Modeling the dispersal of Levantine Intermediate Water and its role in Mediterranean deep water formation

    Science.gov (United States)

    Wu, Peili; Haines, Keith

    1996-03-01

    This paper demonstrates the importance of Levantine Intermediate Water (LIW) in the deep water formation process in the Mediterranean using the modular ocean general circulation model at 0.25° resolution, 19 vertical levels, over the entire Mediterranean with an open Gibraltar strait. LIW formation is strongly prescribed in the Rhodes Gyre region by Haney [1971] relaxation, while in other regions, surface salinity relaxation is much reduced by applying the `mixed' thermohaline surface boundary conditions. Isopycnal diagnostics are used to trace water mass movements, and volume fluxes are monitored at straits. Low viscosity and diffusion are used to permit baroclinic eddies to play a role in water mass dispersal. The overall water budget is measured by an average flux at Gibraltar of 0.8 Sv, of which 0.7 Sv is exchanged with the eastern basin at Sicily. LIW (density around 28.95) spreads rapidly after formation throughout the entire Levantine due to baroclinic eddies. Toward the west, LIW accumulates in the northern and central Ionian, with some entering the Adriatic through Otranto and some mixing southward in eddies and exiting to the western Mediterranean through Sicily. LIW is converted to deep water in the south Adriatic at an average rate of 0.4 Sv. Water exchange through the Otranto strait appears to be buoyancy driven, with a strong bias to the end of winter (March-April), while at Sicily the exchange has a strong symmetric seasonal cycle, with maximum transport of 1.1 Sv in December indicating the effects of wind driving. LIW pathways in the west are complex and variable. In the Tyrrhenian, intermediate water becomes uniform on isopycnal surfaces due to eddy stirring. West of Sardinia, two LIW boundary currents are formed in the Balearic basin; one flows northward up the west coast of Sardinia and Corsica, and one westward along the northern African coast. The northward current is consistent with observations, while the westward current is intermittent for

  16. Sustainable Poly(Ionic Liquids) for CO2 Capture Based on Deep Eutectic Monomers

    KAUST Repository

    Isik, Mehmet; Zulfiqar, Sonia; Edhaim, Fatimah; Ruiperez, Fernando; Rothenberger, Alexander; Mecerreyes, David

    2016-01-01

    The design of high performance solid sorbent materials for CO2 capture is a technology which has been employed to mitigate global warming. However, the covalent incorporation of functionalities into polymeric supports usually involves multistep energy-intensive chemical processes. This fact makes the net CO2 balance of the materials negative even though they possess good properties as CO2 sorbents. Here we show a new family of polymers which are based on amines, amidoximes, and natural carboxylic acids and can be obtained using sustainable low energy processes. Thus, deep eutectic monomers based on natural carboxylic acids, amidoximes, and amines have been prepared by just mixing with cholinium type methacrylic ammonium monomer. The formation of deep eutectic monomers was confirmed by differential scanning calorimetry measurements. In all cases, the monomers displayed glass transition temperatures well below room temperature. Computational studies revealed that the formation of eutectic complexes lengthens the distance between the cation and the anion causing charge delocalization. The liquid nature of the resulting deep eutectic monomers (DEMs) made it possible to conduct a fast photopolymerization process to obtain the corresponding poly(ionic liquids). Materials were characterized by means of nuclear magnetic resonance, differential scanning calorimetry, thermogravimetric analysis, and X-ray diffraction to evaluate the properties of the polymers. The polymers were then used as solid sorbents for CO2 capture. It has been shown that the polymers prepared with citric acid displayed better performance both experimentally and computationally. The current endeavor showed that sustainable poly(ionic liquids) based on deep eutectic monomers can be easily prepared to produce low-energy-cost alternatives to the materials currently being researched for CO2 capture. © 2016 American Chemical Society.

  17. Sustainable Poly(Ionic Liquids) for CO2 Capture Based on Deep Eutectic Monomers

    KAUST Repository

    Isik, Mehmet

    2016-10-05

    The design of high performance solid sorbent materials for CO2 capture is a technology which has been employed to mitigate global warming. However, the covalent incorporation of functionalities into polymeric supports usually involves multistep energy-intensive chemical processes. This fact makes the net CO2 balance of the materials negative even though they possess good properties as CO2 sorbents. Here we show a new family of polymers which are based on amines, amidoximes, and natural carboxylic acids and can be obtained using sustainable low energy processes. Thus, deep eutectic monomers based on natural carboxylic acids, amidoximes, and amines have been prepared by just mixing with cholinium type methacrylic ammonium monomer. The formation of deep eutectic monomers was confirmed by differential scanning calorimetry measurements. In all cases, the monomers displayed glass transition temperatures well below room temperature. Computational studies revealed that the formation of eutectic complexes lengthens the distance between the cation and the anion causing charge delocalization. The liquid nature of the resulting deep eutectic monomers (DEMs) made it possible to conduct a fast photopolymerization process to obtain the corresponding poly(ionic liquids). Materials were characterized by means of nuclear magnetic resonance, differential scanning calorimetry, thermogravimetric analysis, and X-ray diffraction to evaluate the properties of the polymers. The polymers were then used as solid sorbents for CO2 capture. It has been shown that the polymers prepared with citric acid displayed better performance both experimentally and computationally. The current endeavor showed that sustainable poly(ionic liquids) based on deep eutectic monomers can be easily prepared to produce low-energy-cost alternatives to the materials currently being researched for CO2 capture. © 2016 American Chemical Society.

  18. Learning speaker-specific characteristics with a deep neural architecture.

    Science.gov (United States)

    Chen, Ke; Salman, Ahmad

    2011-11-01

    Speech signals convey various yet mixed information ranging from linguistic to speaker-specific information. However, most of acoustic representations characterize all different kinds of information as whole, which could hinder either a speech or a speaker recognition (SR) system from producing a better performance. In this paper, we propose a novel deep neural architecture (DNA) especially for learning speaker-specific characteristics from mel-frequency cepstral coefficients, an acoustic representation commonly used in both speech recognition and SR, which results in a speaker-specific overcomplete representation. In order to learn intrinsic speaker-specific characteristics, we come up with an objective function consisting of contrastive losses in terms of speaker similarity/dissimilarity and data reconstruction losses used as regularization to normalize the interference of non-speaker-related information. Moreover, we employ a hybrid learning strategy for learning parameters of the deep neural networks: i.e., local yet greedy layerwise unsupervised pretraining for initialization and global supervised learning for the ultimate discriminative goal. With four Linguistic Data Consortium (LDC) benchmarks and two non-English corpora, we demonstrate that our overcomplete representation is robust in characterizing various speakers, no matter whether their utterances have been used in training our DNA, and highly insensitive to text and languages spoken. Extensive comparative studies suggest that our approach yields favorite results in speaker verification and segmentation. Finally, we discuss several issues concerning our proposed approach.

  19. Dispersion of deep-sea hydrothermal vent effluents and larvae by submesoscale and tidal currents

    Science.gov (United States)

    Vic, Clément; Gula, Jonathan; Roullet, Guillaume; Pradillon, Florence

    2018-03-01

    Deep-sea hydrothermal vents provide sources of geochemical materials that impact the global ocean heat and chemical budgets, and support complex biological communities. Vent effluents and larvae are dispersed and transported long distances by deep ocean currents, but these currents are largely undersampled and little is known about their variability. Submesoscale (0.1-10 km) currents are known to play an important role for the dispersion of biogeochemical materials in the ocean surface layer, but their impact for the dispersion in the deep ocean is unknown. Here, we use a series of nested regional oceanic numerical simulations with increasing resolution (from δx = 6 km to δx = 0.75 km) to investigate the structure and variability of highly-resolved deep currents over the Mid-Atlantic Ridge (MAR) and their role on the dispersion of the Lucky Strike hydrothermal vent effluents and larvae. We shed light on a submesoscale regime of oceanic turbulence over the MAR at 1500 m depth, contrasting with open-ocean - i.e., far from topographic features - regimes of turbulence, dominated by mesoscales. Impacts of submesoscale and tidal currents on larval dispersion and connectivity among vent populations are investigated by releasing neutrally buoyant Lagrangian particles at the Lucky Strike hydrothermal vent. Although the absolute dispersion is overall not sensitive to the model resolution, submesoscale currents are found to significantly increase both the horizontal and vertical relative dispersion of particles at O(1-10) km and O(1-10) days, resulting in an increased mixing of the cloud of particles. A fraction of particles are trapped in submesoscale coherent vortices, which enable transport over long time and distances. Tidal currents and internal tides do not significantly impact the horizontal relative dispersion. However, they roughly double the vertical dispersion. Specifically, particles undergo strong tidally-induced mixing close to rough topographic features

  20. A simple model for the dispersion of radioactive wastes dumped on the deep-sea bed

    International Nuclear Information System (INIS)

    Shepherd, J.G.

    1976-01-01

    A simple model has been developed for the dispersion of radioactive materials in a closed and finite ocean. It allows for the simultaneous action of both diffusion and horizontal (but not vertical) advection, and thus avoids the major limitations of previous models. It is sufficiently versatile to handle non-Fickian diffusion and radioactive decay, but requires numerical integration using some semi-empirical form for the Green function of diffusion from a point source. The model has been used to estimate equilibrium concentrations of radioactive materials in sea water arising from the continuous release of material from a dump on the bottom of the deep ocean, using parameters appropriate for the North Atlantic. It is found that except under rather extreme conditions the surface concentrations do not exceed the long-term average value which would be established in a perfectly mixed ocean. The concentrations are also rather insensitive to the values of the diffusion and advection parameters used, except for that for vertical diffusion, but depend strongly on the overall removal rate of material from the ocean, including processes other than radioactive decay. It is suggested that safety assessments of deep-sea dumping should utilize estimates of the environmental capacities of the oceans based on the long-term 'well-mixed' average concentrations (which are very easily calculated) using a safety factor of no more than ten to allow for the possible effects of pluming and upwelling. (author)

  1. Deep Seawater Intrusion Enhanced by Geothermal Through Deep Faults in Xinzhou Geothermal Field in Guangdong, China

    Science.gov (United States)

    Lu, G.; Ou, H.; Hu, B. X.; Wang, X.

    2017-12-01

    This study investigates abnormal sea water intrusion from deep depth, riding an inland-ward deep groundwater flow, which is enhanced by deep faults and geothermal processes. The study site Xinzhou geothermal field is 20 km from the coast line. It is in southern China's Guangdong coast, a part of China's long coastal geothermal belt. The geothermal water is salty, having fueled an speculation that it was ancient sea water retained. However, the perpetual "pumping" of the self-flowing outflow of geothermal waters might alter the deep underground flow to favor large-scale or long distant sea water intrusion. We studied geochemical characteristics of the geothermal water and found it as a mixture of the sea water with rain water or pore water, with no indication of dilution involved. And we conducted numerical studies of the buoyancy-driven geothermal flow in the deep ground and find that deep down in thousand meters there is favorable hydraulic gradient favoring inland-ward groundwater flow, allowing seawater intrude inland for an unusually long tens of kilometers in a granitic groundwater flow system. This work formed the first in understanding geo-environment for deep ground water flow.

  2. 14C age reassessment of groundwater from the discharge zone due to cross-flow mixing in the deep confined aquifer

    Science.gov (United States)

    Mao, Xumei; Wang, Hua; Feng, Liang

    2018-05-01

    In a groundwater flow system, the age of groundwater should gradually increase from the recharge zone to the discharge zone within the same streamline. However, it is occasionally observed that the groundwater age becomes younger in the discharge zone in the piedmont alluvial plain, and the oldest age often appears in the middle of the plain. A new set of groundwater chemistry and isotopes was employed to reassess the groundwater 14C ages from the discharge zone in the North China Plain (NCP). Carbonate precipitation, organic matter oxidation and cross-flow mixing in the groundwater from the recharge zone to the discharge zone are recognized according to the corresponding changes of HCO3- (or DIC) and δ13C in the same streamline of the third aquifer of the NCP. The effects of carbonate precipitation and organic matter oxidation are calibrated with a 13C mixing model and DIC correction, but these corrected 14C ages seem unreasonable because they grow younger from the middle plain to the discharge zone in the NCP. The relationship of Cl- content and the recharge distance is used to estimate the expected Cl- content in the discharge zone, and ln(a14C)/Cl is proposed to correct the a14C in groundwater for the effect of cross-flow mixing. The 14C ages were reassessed with the corrected a14C due to the cross-flow mixing varying from 1.25 to 30.58 ka, and the groundwater becomes older gradually from the recharge zone to the discharge zone. The results suggest that the reassessed 14C ages are more reasonable for the groundwater from the discharge zone due to cross-flow mixing.

  3. Deep Learning in Neuroradiology.

    Science.gov (United States)

    Zaharchuk, G; Gong, E; Wintermark, M; Rubin, D; Langlotz, C P

    2018-02-01

    Deep learning is a form of machine learning using a convolutional neural network architecture that shows tremendous promise for imaging applications. It is increasingly being adapted from its original demonstration in computer vision applications to medical imaging. Because of the high volume and wealth of multimodal imaging information acquired in typical studies, neuroradiology is poised to be an early adopter of deep learning. Compelling deep learning research applications have been demonstrated, and their use is likely to grow rapidly. This review article describes the reasons, outlines the basic methods used to train and test deep learning models, and presents a brief overview of current and potential clinical applications with an emphasis on how they are likely to change future neuroradiology practice. Facility with these methods among neuroimaging researchers and clinicians will be important to channel and harness the vast potential of this new method. © 2018 by American Journal of Neuroradiology.

  4. Deep vein thrombosis as a paraneoplastic syndrome

    Directory of Open Access Journals (Sweden)

    Klačar Marija

    2014-01-01

    Full Text Available Introduction: Several conditions represent the risk factor for deep vein thrombosis (DVT but sometimes it occurs with no apparent reason. DVT usually involve lower extremities. It can be a component of paraneoplastic syndrome, and occasionally it is the first manifestation of malignancy. Case report: Fifty-five years old male reported to his general practitioner with history of painless right leg swelling of three weeks duration. He denied leg trauma or any other hardship. The patient had a long history of hypertension and took his medications irregularly. Family history was positive for cardiovascular diseases but negative for metabolic diseases or malignancies. He was a smoker and physically active. Physical examination revealed right calf swelling without skin discoloration, distention of superficial veins or trophic changes. Pulses of magistral arteries of the leg were symmetrical, Homans' sign was positive on the right leg. The rest of the physical examination was normal, except for the blood pressure. He was referred to vascular surgeon with the clinical diagnosis of femoro- popliteal phlebothrombosis of the right leg. Vascular surgeon performed the Color duplex scan of the lower extremities which confirmed the diagnosis. The patient was treated with low-molecular-weight heparin. The swelling significantly subsided after two weeks of therapy, but then patient fell and fractured left ramus of ischial bone. X-ray examination of pelvis revealed both fracture line and osteoblastic deposits in pelvis and the fracture was pronounced pathological. In order to localize the primary tumor, subsequent tests included chest X-ray, abdominal and pelvic ultrasound and digitorectal examination of prostate were performed. The results of all of the above mentioned examinations were within normal ranges, including routine blood tests. Skeletal scintigraphy revealed multiple secondary deposits in pelvic bones, vertebral column and ribs. Tumor markers' values

  5. Energy droughts in a 100% renewable electricity mix

    Science.gov (United States)

    Raynaud, Damien; Hingray, Benoît; François, Baptiste; Creutin, Jean-Dominique

    2017-04-01

    During the 21st conference of parties, 175 countries agreed on limiting the temperature increase due to global warming to 2°C above preindustrial levels. Such an ambitious goal necessitates a deep transformation of our society in order to reduce greenhouse gas (GHG) emissions. Europe has started its energy transition years ago by, for instance, increasing the share of renewables in the European electricity generation and should continue in this direction. Variable renewable energies (VRE) and especially those driven by weather conditions (namely wind, solar and hydro power from river flow), are expected to play a key role in achieving the GHG reduction target. However, these renewables are often criticized for their intermittency and for the resulting difficult integration in the power supply system, especially for large shares of VRE in the energy mix. Assessing the feasibility of electricity generation using large contributions of VRE requires a deep understanding and characterization of the VRE spatiotemporal variations. In the last decade, many studies have focused on the short-term intermittency of VRE generation, but the persistency and the characteristics of periods of low/high electricity generation have been rarely studied. Yet, these particular situations require some demanding adaptations of the power supply system in term of back-up sources or production curtailment respectively. This study focuses on what we call "energy droughts" which, by analogy with hydrological or meteorological droughts, are defined as periods of very low energy production. We consider in turn "energy droughts" associated to wind, solar and hydro power (run-of-the-river). Their characteristics are estimated for 12 European regions being subjected to different climatic regimes. For each region and energy source, "droughts" are evaluated from a 30-yr time series of power generation (1983-2012). These series are simulated by using a suite of weather-to-energy conversion models with

  6. The Oceanic Flux Program: A three decade time-series of particle flux in the deep Sargasso Sea

    Science.gov (United States)

    Weber, J. C.; Conte, M. H.

    2010-12-01

    The Oceanic Flux Program (OFP), 75 km SE of Bermuda, is the longest running time-series of its kind. Initiated in 1978, the OFP has produced an unsurpassed, nearly continuous record of temporal variability in deep ocean fluxes, with a >90% temporal coverage at 3200m depth. The OFP, in conjunction with the co-located Bermuda-Atlantic Time Series (BATS) and the Bermuda Testbed Mooring (BTM) time-series, has provided key observations enabling detailed assessment of how seasonal and non-seasonal variability in the deep ocean is linked with the overlying physical and biogeochemical environment. This talk will focus on the short-term flux variability that overlies the seasonal flux pattern in the Sargasso Sea, emphasizing episodic extreme flux events. Extreme flux events are responsible for much of the year-to-year variability in mean annual flux and are most often observed during early winter and late spring when surface stratification is weak or transient. In addition to biological phenomena (e.g. salp blooms), passage of productive meso-scale features such as eddies, which alter surface water mixing characteristics and surface export fluxes, may initiate some extreme flux events. Yet other productive eddies show a minimal influence on the deep flux, underscoring the importance of upper ocean ecosystem structure and midwater processes on the coupling between the surface ocean environment and deep fluxes. Using key organic and inorganic tracers, causative processes that influence deep flux generation and the strength of the coupling with the surface ocean environment can be identified.

  7. Vienna convention on civil liability for nuclear damage and optional protocol concerning the compulsory settlement of disputes. Status lists as of 12 September 2000. Signature, ratification, accession, or succession. Declarations/reservations made upon expressing consent to be bound and objections thereto. Declarations/reservations made upon signature

    International Nuclear Information System (INIS)

    2000-01-01

    The document provides the status list to the Protocol to Amend the Vienna Convention on Civil Liability for Nuclear Damage and optional protocol concerning the compulsory settlement of disputes as of 12 September 2000

  8. Suspended sediment dynamics in a large-scale turbidity current: Direct measurements from the deep-water Congo Canyon

    Science.gov (United States)

    Simmons, S.; Azpiroz, M.; Cartigny, M.; Clare, M. A.; Parsons, D. R.; Sumner, E.; Talling, P. J.

    2016-12-01

    Turbidity currents that transport sediment to the deep ocean deposit a greater volume of sediment than any other process on Earth. To date, only a handful of studies have directly measured turbidity currents, with flow durations ranging from a few minutes to a few hours. Our understanding of turbidity current dynamics is therefore largely derived from scaled laboratory experiments and numerical modelling. Recent years have seen the first field-scale measurements of depth-resolved velocity profiles, but sediment concentration (a key parameter for turbidity currents) remains elusive. Here, we present high resolution measurements of deep-water turbidity currents from the Congo Canyon; one of the world's largest submarine canyons. Direct measurements using acoustic Doppler current profilers (ADCPs) show that flows can last for many days, rather than hours as seen elsewhere, and provide the first quantification of concentration and grain size within deep-water turbidity currents.Velocity and backscatter were measured at 5 second intervals by an ADCP suspended 80 m above the canyon floor, at 2000 m water depth. A novel inversion method using multiple ADCP frequencies enabled quantification of sediment concentration and grain size within the flows. We identify high concentrations of coarse sediment within a thin frontal cell, which outruns a thicker, trailing body. Thus, the flows grow in length while propagating down-canyon. This is distinct from classical models and other field-scale measurements of turbidity currents. The slow-moving body is dominated by suspended fine-grained sediment. The body mixes with the surrounding fluid leaving diffuse clouds of sediment that persist for days after initial entrainment. Ambient tidal flow also controls the mixing within the body and the surrounding fluid. Our results provide a new quantification of suspended sediment within flows and the interaction with the surrounding fluid.

  9. Temperature impacts on deep-sea biodiversity.

    Science.gov (United States)

    Yasuhara, Moriaki; Danovaro, Roberto

    2016-05-01

    Temperature is considered to be a fundamental factor controlling biodiversity in marine ecosystems, but precisely what role temperature plays in modulating diversity is still not clear. The deep ocean, lacking light and in situ photosynthetic primary production, is an ideal model system to test the effects of temperature changes on biodiversity. Here we synthesize current knowledge on temperature-diversity relationships in the deep sea. Our results from both present and past deep-sea assemblages suggest that, when a wide range of deep-sea bottom-water temperatures is considered, a unimodal relationship exists between temperature and diversity (that may be right skewed). It is possible that temperature is important only when at relatively high and low levels but does not play a major role in the intermediate temperature range. Possible mechanisms explaining the temperature-biodiversity relationship include the physiological-tolerance hypothesis, the metabolic hypothesis, island biogeography theory, or some combination of these. The possible unimodal relationship discussed here may allow us to identify tipping points at which on-going global change and deep-water warming may increase or decrease deep-sea biodiversity. Predicted changes in deep-sea temperatures due to human-induced climate change may have more adverse consequences than expected considering the sensitivity of deep-sea ecosystems to temperature changes. © 2014 Cambridge Philosophical Society.

  10. Abundance of gap junctions at glutamatergic mixed synapses in adult Mosquitofish spinal cord neurons

    Directory of Open Access Journals (Sweden)

    Jose L Serrano-Velez

    2014-06-01

    Full Text Available Dye-coupling, whole-mount immunohistochemistry for gap junction channel protein connexin 35 (Cx35, and freeze-fracture replica immunogold labeling (FRIL reveal an abundance of electrical synapses/gap junctions at glutamatergic mixed synapses in the 14th spinal segment that innervates the adult male gonopodium of Western Mosquitofish, Gambusia affinis (Mosquitofish.To study gap junctions’ role in fast motor behavior, we used a minimally-invasive neural-tract-tracing technique to introduce gap junction-permeant or -impermeant dyes into deep muscles controlling the gonopodium of the adult male Mosquitofish, a teleost fish that rapidly transfers (complete in 50 of the 62 gap junctions at mixed synapses are in the 14th spinal segment.Our results support and extend studies showing gap junctions at mixed synapses in spinal cord segments involved in control of genital reflexes in rodents, and they suggest a link between mixed synapses and fast motor behavior. The findings provide a basis for studies of specific roles of spinal neurons in the generation/regulation of sex-specific behavior and for studies of gap junctions’ role in regulating fast motor behavior. Finally, the CoPA IN provides a novel candidate neuron for future studies of gap junctions and neural control of fast motor behaviors.

  11. Extreme Longevity in Proteinaceous Deep-Sea Corals

    Energy Technology Data Exchange (ETDEWEB)

    Roark, E B; Guilderson, T P; Dunbar, R B; Fallon, S J; Mucciarone, D A

    2009-02-09

    Deep-sea corals are found on hard substrates on seamounts and continental margins world-wide at depths of 300 to {approx}3000 meters. Deep-sea coral communities are hotspots of deep ocean biomass and biodiversity, providing critical habitat for fish and invertebrates. Newly applied radiocarbon age date from the deep water proteinaceous corals Gerardia sp. and Leiopathes glaberrima show that radial growth rates are as low as 4 to 35 {micro}m yr{sup -1} and that individual colony longevities are on the order of thousands of years. The management and conservation of deep sea coral communities is challenged by their commercial harvest for the jewelry trade and damage caused by deep water fishing practices. In light of their unusual longevity, a better understanding of deep sea coral ecology and their interrelationships with associated benthic communities is needed to inform coherent international conservation strategies for these important deep-sea ecosystems.

  12. New optimized drill pipe size for deep-water, extended reach and ultra-deep drilling

    Energy Technology Data Exchange (ETDEWEB)

    Jellison, Michael J.; Delgado, Ivanni [Grant Prideco, Inc., Hoston, TX (United States); Falcao, Jose Luiz; Sato, Ademar Takashi [PETROBRAS, Rio de Janeiro, RJ (Brazil); Moura, Carlos Amsler [Comercial Perfuradora Delba Baiana Ltda., Rio de Janeiro, RJ (Brazil)

    2004-07-01

    A new drill pipe size, 5-7/8 in. OD, represents enabling technology for Extended Reach Drilling (ERD), deep water and other deep well applications. Most world-class ERD and deep water wells have traditionally been drilled with 5-1/2 in. drill pipe or a combination of 6-5/8 in. and 5-1/2 in. drill pipe. The hydraulic performance of 5-1/2 in. drill pipe can be a major limitation in substantial ERD and deep water wells resulting in poor cuttings removal, slower penetration rates, diminished control over well trajectory and more tendency for drill pipe sticking. The 5-7/8 in. drill pipe provides a significant improvement in hydraulic efficiency compared to 5-1/2 in. drill pipe and does not suffer from the disadvantages associated with use of 6-5/8 in. drill pipe. It represents a drill pipe assembly that is optimized dimensionally and on a performance basis for casing and bit programs that are commonly used for ERD, deep water and ultra-deep wells. The paper discusses the engineering philosophy behind 5-7/8 in. drill pipe, the design challenges associated with development of the product and reviews the features and capabilities of the second-generation double-shoulder connection. The paper provides drilling case history information on significant projects where the pipe has been used and details results achieved with the pipe. (author)

  13. Determination of deep water circulation in the East Atlantic Ocean by means of a box-model based evaluation of C-14 measurements and other tracer data

    International Nuclear Information System (INIS)

    Schlitzer, R.

    1984-01-01

    Radiocarbon (C-14) measurements proved to be an efficient means of determining the average, large-area deep water circulation in the Atlantic Ocean. The thesis under review explains and discusses measurements carried out in the equatorial West Atlantic and North Atlantic Ocean. The samples have been taken during mission 56 of the RS 'meteor' in spring 1981. The gas has been obtained by vacuum extraction and the measurements have been performed in proportional counter tubes, the error to be accounted for amounting to 2per mille. These measured data, together with measurements of the potential temperatures, the silicate and CO 2 concentrations, and measured data from the South-East Atlantic Ocean, have been used to calculate on the basis of a box model of the Atlantic Ocean the deep water flow from the West to the East Atlantic Ocean, the deep water circulation between the various East Atlantic basins, and the turbulent diffusion coefficients required to parameterize the deep water mixing processes. (orig./HP) [de

  14. Deep Reinforcement Learning: An Overview

    OpenAIRE

    Li, Yuxi

    2017-01-01

    We give an overview of recent exciting achievements of deep reinforcement learning (RL). We discuss six core elements, six important mechanisms, and twelve applications. We start with background of machine learning, deep learning and reinforcement learning. Next we discuss core RL elements, including value function, in particular, Deep Q-Network (DQN), policy, reward, model, planning, and exploration. After that, we discuss important mechanisms for RL, including attention and memory, unsuperv...

  15. Prokaryotic degradation of high molecular weight dissolved organic matter in the deep-sea waters of NW Mediterranean Sea under in situ temperature and pressure conditions during contrasted hydrological conditions

    Science.gov (United States)

    Tamburini, C.; Boutrif, M.; Garel, M.; Sempéré, R.; Repeta, D.; Charriere, B.; Nerini, D.; Panagiotopoulos, C.

    2016-02-01

    The contribution of the semi-labile dissolved organic carbon (DOC) to the global prokaryotic production has been assessed in very few previous studies. Some experiments show rapid utilization of semi-reactive DOC by prokaryotes, while other experiments show almost no utilization at all. However, all these studies did not take into account the role of hydrostatic pressure for the degradation of organic matter. In this study, we investigate (1) the degradation of "natural" high molecular weight DOM HMW-DOM (obtained after ultrafiltration) and (2) the uptake of labeled extracellular polymeric substances (3H-EPS) incubated with deep-sea water samples (2000 m-depth, NW Mediterranean Sea) under in situ pressure conditions (HP) and under atmospheric compression after decompression of the deep samples (ATM) during stratified and mixed water conditions (deep sea convection). Our results indicated that during HP incubations DOC exhibited the highest degradation rates (kHP DOC = 0.82 d-1) compared to the ATM conditions were no or few degradation was observed (kATM DOC= 0.007 d-1). An opposite trend was observed for the HP incubations from mixed deep water masses. HP incubation measurements displayed the lowest DOC degradation (kHP DOC=0.031 d-1) compared to the ATM conditions (kATM DOC=0.62 d-1). These results imply the presence of allochthonous prokaryotic cells in deep-sea samples after a winter water mass convection. Same trends were found using 3H-EPS uptake rates which were higher at HP than at ATM conditions during stratified period conditions whereas the opposite patterns were observed during deep-sea convection event. Moreover, we found than Euryarchaea were the main contributors to 3H-EPS assimilation at 2000m-depth, representing 58% of the total cells actively assimilating 3H-EPS. This study demonstrates that remineralization rates of semi-labile DOC in deep NW Med. Sea are controlled by the prokaryotic communities, which are influenced by the hydrological

  16. Land Cover Classification via Multitemporal Spatial Data by Deep Recurrent Neural Networks

    Science.gov (United States)

    Ienco, Dino; Gaetano, Raffaele; Dupaquier, Claire; Maurel, Pierre

    2017-10-01

    Nowadays, modern earth observation programs produce huge volumes of satellite images time series (SITS) that can be useful to monitor geographical areas through time. How to efficiently analyze such kind of information is still an open question in the remote sensing field. Recently, deep learning methods proved suitable to deal with remote sensing data mainly for scene classification (i.e. Convolutional Neural Networks - CNNs - on single images) while only very few studies exist involving temporal deep learning approaches (i.e Recurrent Neural Networks - RNNs) to deal with remote sensing time series. In this letter we evaluate the ability of Recurrent Neural Networks, in particular the Long-Short Term Memory (LSTM) model, to perform land cover classification considering multi-temporal spatial data derived from a time series of satellite images. We carried out experiments on two different datasets considering both pixel-based and object-based classification. The obtained results show that Recurrent Neural Networks are competitive compared to state-of-the-art classifiers, and may outperform classical approaches in presence of low represented and/or highly mixed classes. We also show that using the alternative feature representation generated by LSTM can improve the performances of standard classifiers.

  17. DeepMirTar: a deep-learning approach for predicting human miRNA targets.

    Science.gov (United States)

    Wen, Ming; Cong, Peisheng; Zhang, Zhimin; Lu, Hongmei; Li, Tonghua

    2018-06-01

    MicroRNAs (miRNAs) are small noncoding RNAs that function in RNA silencing and post-transcriptional regulation of gene expression by targeting messenger RNAs (mRNAs). Because the underlying mechanisms associated with miRNA binding to mRNA are not fully understood, a major challenge of miRNA studies involves the identification of miRNA-target sites on mRNA. In silico prediction of miRNA-target sites can expedite costly and time-consuming experimental work by providing the most promising miRNA-target-site candidates. In this study, we reported the design and implementation of DeepMirTar, a deep-learning-based approach for accurately predicting human miRNA targets at the site level. The predicted miRNA-target sites are those having canonical or non-canonical seed, and features, including high-level expert-designed, low-level expert-designed, and raw-data-level, were used to represent the miRNA-target site. Comparison with other state-of-the-art machine-learning methods and existing miRNA-target-prediction tools indicated that DeepMirTar improved overall predictive performance. DeepMirTar is freely available at https://github.com/Bjoux2/DeepMirTar_SdA. lith@tongji.edu.cn, hongmeilu@csu.edu.cn. Supplementary data are available at Bioinformatics online.

  18. Extrusion-mixing compared with hand-mixing of polyether impression materials?

    Science.gov (United States)

    McMahon, Caroline; Kinsella, Daniel; Fleming, Garry J P

    2010-12-01

    The hypotheses tested were two-fold (a) whether altering the base:catalyst ratio influences working time, elastic recovery and strain in compression properties of a hand-mixed polyether impression material and (b) whether an extrusion-mixed polyether impression material would have a significant advantage over a hand-mixed polyether impression material mixed to the optimum base:catalyst ratio. The polyether was hand-mixed at the optimum (manufacturers recommended) base:catalyst ratios (7:1) and further groups were made by increasing or decreasing the catalyst length by 25%. Additionally specimens were also made from an extrusion-mixed polyether impression material and compared with the optimum hand-mixed base:catalyst ratio. A penetrometer assembly was used to measure the working time (n=5). Five cylindrical specimens for each hand-mixed and extrusion mixed group investigated were employed for elastic recovery and strain in compression testing. Hand-mixing polyether impression materials with 25% more catalyst than that recommended significantly decreased the working time while hand-mixing with 25% less catalyst than that recommended significantly increased the strain in compression. The extrusion-mixed polyether impression material provided similar working time, elastic recovery and strain in compression to the hand-mixed polyether mixed at the optimum base:catalyst ratio.

  19. Fiscal 1999 research result report. Basic research on the evaluation method of deep water by fine algae; 1999 nendo bisai sorui wo mochiita shinsosui hyokaho ni kansuru kisoteki kenkyu hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Basic research was made on establishment of a bioassay for testing the effect of deep water on surface biota. Mixing of surface water and deep water with high-concentration nutrient salts has effect on fine algae (phytoplankton) immediately. In this research, based on conventional AGP (algae growth potential) method as water quality evaluation method by fine algae, the multiplication potential of 13 strains of algae in Kochi's and Toyama's deep water was evaluated by using the increase rate of the number of cells. The research result showed that (1) deep water has the potential increasing cell concentrations of every fine algae to several times or over ten times as compared with surface water, (2) most of both nitrogen and phosphorus in deep water are consumed during the above process, (3) cell concentrations of both harmful and usable species increase, and (4) although no difference in mean potential is found between Kochi's and Toyama's deep water, the patterns of strains promoting multiplication are different between them. (NEDO)

  20. Deep Unfolding for Topic Models.

    Science.gov (United States)

    Chien, Jen-Tzung; Lee, Chao-Hsi

    2018-02-01

    Deep unfolding provides an approach to integrate the probabilistic generative models and the deterministic neural networks. Such an approach is benefited by deep representation, easy interpretation, flexible learning and stochastic modeling. This study develops the unsupervised and supervised learning of deep unfolded topic models for document representation and classification. Conventionally, the unsupervised and supervised topic models are inferred via the variational inference algorithm where the model parameters are estimated by maximizing the lower bound of logarithm of marginal likelihood using input documents without and with class labels, respectively. The representation capability or classification accuracy is constrained by the variational lower bound and the tied model parameters across inference procedure. This paper aims to relax these constraints by directly maximizing the end performance criterion and continuously untying the parameters in learning process via deep unfolding inference (DUI). The inference procedure is treated as the layer-wise learning in a deep neural network. The end performance is iteratively improved by using the estimated topic parameters according to the exponentiated updates. Deep learning of topic models is therefore implemented through a back-propagation procedure. Experimental results show the merits of DUI with increasing number of layers compared with variational inference in unsupervised as well as supervised topic models.

  1. Physical oceanographic characteristics influencing the dispersion of dissolved tracers released at the sea floor in selected deep ocean study areas

    International Nuclear Information System (INIS)

    Kupferman, S.L.; Moore, D.E.

    1981-02-01

    Scenarios which follow the development in space and time of the concentration field of a dissolved tracer released at the sea floor are presented for a Pacific and two Atlantic study areas. The scenarios are closely tied to available data by means of simple analytical models and proceed in stages from short time and space scales in the immediate vicinity of a release point to those scales characteristic of ocean basins. The concepts of internal mixing time and residence time in the benthic mixed layer, useful for developing an intuitive feeling for the behavior of a tracer in this feature, are introduced and discussed. We also introduce the concept of domain of occupation, which is useful in drawing distinctions between mixing and stirring in the ocean. From this study it is apparent that reliable estimation of mixing will require careful consideration of the dynamics of the eddy fields in the ocean. Another area in which more information is urgently needed is in the relation of deep isopycnal structure and bottom topography to local near-bottom circulation

  2. Deep convective clouds at the tropopause

    Directory of Open Access Journals (Sweden)

    H. H. Aumann

    2011-02-01

    Full Text Available Data from the Atmospheric Infrared Sounder (AIRS on the EOS Aqua spacecraft each day show tens of thousands of Cold Clouds (CC in the tropical oceans with 10 μm window channel brightness temperatures colder than 225 K. These clouds represent a mix of cold anvil clouds and Deep Convective Clouds (DCC. This mix can be separated by computing the difference between two channels, a window channel and a channel with strong CO2 absorption: for some cold clouds this difference is negative, i.e. the spectra for some cold clouds are inverted. We refer to cold clouds with spectra which are more than 2 K inverted as DCCi2. Associated with DCCi2 is a very high rain rate and a local upward displacement of the tropopause, a cold "bulge", which can be seen directly in the brightness temperatures of AIRS and Advanced Microwave Sounding Unit (AMSU temperature sounding channels in the lower stratosphere. The very high rain rate and the local distortion of the tropopause indicate that DCCi2 objects are associated with severe storms. Significant long-term trends in the statistical properties of DCCi2 could be interesting indicators of climate change. While the analysis of the nature and physical conditions related to DCCi2 requires hyperspectral infrared and microwave data, the identification of DCCi2 requires only one good window channel and one strong CO2 sounding channel. This suggests that improved identification of severe storms with future advanced geostationary satellites could be accomplished with the addition of one or two narrow band channels.

  3. WHATS-3: An Improved Flow-Through Multi-bottle Fluid Sampler for Deep-Sea Geofluid Research

    Directory of Open Access Journals (Sweden)

    Junichi Miyazaki

    2017-06-01

    Full Text Available Deep-sea geofluid systems, such as hydrothermal vents and cold seeps, are key to understanding subseafloor environments of Earth. Fluid chemistry, especially, provides crucial information toward elucidating the physical, chemical, and biological processes that occur in these ecosystems. To accurately assess fluid and gas properties of deep-sea geofluids, well-designed pressure-tight fluid samplers are indispensable and as such they are important assets of deep-sea geofluid research. Here, the development of a new flow-through, pressure-tight fluid sampler capable of four independent sampling events (two subsamples for liquid and gas analyses from each is reported. This new sampler, named WHATS-3, is a new addition to the WHATS-series samplers and a major upgrade from the previous WHATS-2 sampler with improvements in sample number, valve operational time, physical robustness, and ease of maintenance. Routine laboratory-based pressure tests proved that it is suitable for operation up to 35 MPa pressure. Successful field tests of the new sampler were also carried out in five hydrothermal fields, two in Indian Ocean, and three in Okinawa Trough (max. depth 3,300 m. Relations of Mg and major ion species demonstrated bimodal mixing trends between a hydrothermal fluid and seawater, confirming the high quality of fluids sampled. The newly developed WHATS-3 sampler is well-balanced in sampling capability, field usability, and maintenance feasibility, and can serve as one of the best geofluid samplers available at present to conduct efficient research of deep-sea geofluid systems.

  4. Quasi-Geostrophic Diagnosis of Mixed-Layer Dynamics Embedded in a Mesoscale Turbulent Field

    Science.gov (United States)

    Chavanne, C. P.; Klein, P.

    2016-02-01

    A new quasi-geostrophic model has been developed to diagnose the three-dimensional circulation, including the vertical velocity, in the upper ocean from high-resolution observations of sea surface height and buoyancy. The formulation for the adiabatic component departs from the classical surface quasi-geostrophic framework considered before since it takes into account the stratification within the surface mixed-layer that is usually much weaker than that in the ocean interior. To achieve this, the model approximates the ocean with two constant-stratification layers : a finite-thickness surface layer (or the mixed-layer) and an infinitely-deep interior layer. It is shown that the leading-order adiabatic circulation is entirely determined if both the surface streamfunction and buoyancy anomalies are considered. The surface layer further includes a diabatic dynamical contribution. Parameterization of diabatic vertical velocities is based on their restoring impacts of the thermal-wind balance that is perturbed by turbulent vertical mixing of momentum and buoyancy. The model skill in reproducing the three-dimensional circulation in the upper ocean from surface data is checked against the output of a high-resolution primitive-equation numerical simulation. Correlation between simulated and diagnosed vertical velocities are significantly improved in the mixed-layer for the new model compared to the classical surface quasi-geostrophic model, reaching 0.9 near the surface.

  5. Docker Containers for Deep Learning Experiments

    OpenAIRE

    Gerke, Paul K.

    2017-01-01

    Deep learning is a powerful tool to solve problems in the area of image analysis. The dominant compute platform for deep learning is Nvidia’s proprietary CUDA, which can only be used together with Nvidia graphics cards. The nivida-docker project allows exposing Nvidia graphics cards to docker containers and thus makes it possible to run deep learning experiments in docker containers.In our department, we use deep learning to solve problems in the area of medical image analysis and use docker ...

  6. Auxiliary Deep Generative Models

    DEFF Research Database (Denmark)

    Maaløe, Lars; Sønderby, Casper Kaae; Sønderby, Søren Kaae

    2016-01-01

    Deep generative models parameterized by neural networks have recently achieved state-of-the-art performance in unsupervised and semi-supervised learning. We extend deep generative models with auxiliary variables which improves the variational approximation. The auxiliary variables leave...... the generative model unchanged but make the variational distribution more expressive. Inspired by the structure of the auxiliary variable we also propose a model with two stochastic layers and skip connections. Our findings suggest that more expressive and properly specified deep generative models converge...... faster with better results. We show state-of-the-art performance within semi-supervised learning on MNIST (0.96%), SVHN (16.61%) and NORB (9.40%) datasets....

  7. Accelerating Deep Learning with Shrinkage and Recall

    OpenAIRE

    Zheng, Shuai; Vishnu, Abhinav; Ding, Chris

    2016-01-01

    Deep Learning is a very powerful machine learning model. Deep Learning trains a large number of parameters for multiple layers and is very slow when data is in large scale and the architecture size is large. Inspired from the shrinking technique used in accelerating computation of Support Vector Machines (SVM) algorithm and screening technique used in LASSO, we propose a shrinking Deep Learning with recall (sDLr) approach to speed up deep learning computation. We experiment shrinking Deep Lea...

  8. Distribution of artificial radionuclides in deep sediments of the Mediterranean Sea

    International Nuclear Information System (INIS)

    Garcia-Orellana, J.; Pates, J.M.; Masque, P.; Bruach, J.M.; Sanchez-Cabeza, J.A.

    2009-01-01

    Artificial radionuclides enter the Mediterranean Sea mainly through atmospheric deposition following nuclear weapons tests and the Chernobyl accident, but also through the river discharge of nuclear facility effluents. Previous studies of artificial radionuclides impact of the Mediterranean Sea have focussed on shallow, coastal sediments. However, deep sea sediments have the potential to store and accumulate pollutants, including artificial radionuclides. Deep sea marine sediment cores were collected from Mediterranean Sea abyssal plains (depth > 2000 m) and analysed for 239,240 Pu and 137 Cs to elucidate the concentrations, inventories and sources of these radionuclides in the deepest areas of the Mediterranean. The activity - depth profiles of 210 Pb, together with 14 C dating, indicate that sediment mixing redistributes the artificial radionuclides within the first 2.5 cm of the sedimentary column. The excess 210 Pb inventory was used to normalize 239,240 Pu and 137 Cs inventories for variable sediment fluxes. The 239,240 Pu/ 210 Pb xs ratio was uniform across the entire sea, with a mean value of 1.24 x 10 -3 , indicating homogeneous fallout of 239,240 Pu. The 137 Cs/ 210 Pb xs ratio showed differences between the eastern (0.049) and western basins (0.030), clearly significant impact of deep sea sediments from the Chernobyl accident. The inventory ratios of 239,240 Pu/ 137 Cs were 0.041 and 0.025 in the western and eastern basins respectively, greater than the fallout ratio, 0.021, showing more efficient scavenging of 239,240 Pu in the water column and major sedimentation of 137 Cs in the eastern basin. Although areas with water depths of > 2000 m constitute around 40% of the entire Mediterranean basin, the sediments in these regions only contained 2.7% of the 239,240 Pu and 0.95% of the 137 Cs deposited across the Sea in 2000. These data show that the accumulation of artificial radionuclides in deep Mediterranean environments is much lower than predicted by

  9. A Preliminary Assessment of a Deep Borehole disposal of Spent Fuels

    International Nuclear Information System (INIS)

    Lee, Younmyoung; Jeon, Jongtae

    2014-01-01

    Deep borehole disposal (DBD) of such radioactive waste as spent nuclear fuels (SFs) and other waste forms has been investigating mainly at Sandia National Labs for the US DOE as an alternative option. DBD can give advantages over less deep geological disposal since the disposal of wastes at a great depth where a low degree of permeability in the potentially steady rock condition will be beneficial for nuclide movement. Groundwater in the deep basement rock can even have salinity and less chance to mix with groundwater above. The DBD concept is quite straightforward and even simple: Waste canisters are simply emplaced in the lower 2 km part of the borehole down to 5 km deep. Through this study, a conceptual DBD is assessed for a similar case as the US DOE's approach, in which 400 SF canisters are to be emplaced at a deep bottom between 3km and 5km depths, upon which an additional 1km-thick compacted bentonite is overbuffered, and the remaining upper part of the borehole is backfilled again with a mixture of crushed rock and bentonite. Then, the total 5km-deep borehole has three zones: a disposal zone at the bottom 2km, a buffer zone at the next 1km, and backfill zone at the rest top 2km, as illustrated conceptually in Fig. 1. To demonstrate the feasibility in view of long-term radiological safety, a rough model for a safety assessment of this conceptual deep borehole repository system, providing detailed models for nuclide transport in and around the geosphere and biosphere under normal nuclide release scenarios that can occur after a closure of the repository, has been developed using GoldSim. A simple preliminary result in terms of the dose exposure rate from a safety assessment of the DBD is also presented and compared to the case of direct disposal of SFs in a KBS-3V vertical type repository, carried out in previous studies. For different types and shapes of repositories at each different depth, direct comparison between a DBD and a KBS-3 type disposal of

  10. A Preliminary Assessment of a Deep Borehole disposal of Spent Fuels

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Younmyoung; Jeon, Jongtae [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    Deep borehole disposal (DBD) of such radioactive waste as spent nuclear fuels (SFs) and other waste forms has been investigating mainly at Sandia National Labs for the US DOE as an alternative option. DBD can give advantages over less deep geological disposal since the disposal of wastes at a great depth where a low degree of permeability in the potentially steady rock condition will be beneficial for nuclide movement. Groundwater in the deep basement rock can even have salinity and less chance to mix with groundwater above. The DBD concept is quite straightforward and even simple: Waste canisters are simply emplaced in the lower 2 km part of the borehole down to 5 km deep. Through this study, a conceptual DBD is assessed for a similar case as the US DOE's approach, in which 400 SF canisters are to be emplaced at a deep bottom between 3km and 5km depths, upon which an additional 1km-thick compacted bentonite is overbuffered, and the remaining upper part of the borehole is backfilled again with a mixture of crushed rock and bentonite. Then, the total 5km-deep borehole has three zones: a disposal zone at the bottom 2km, a buffer zone at the next 1km, and backfill zone at the rest top 2km, as illustrated conceptually in Fig. 1. To demonstrate the feasibility in view of long-term radiological safety, a rough model for a safety assessment of this conceptual deep borehole repository system, providing detailed models for nuclide transport in and around the geosphere and biosphere under normal nuclide release scenarios that can occur after a closure of the repository, has been developed using GoldSim. A simple preliminary result in terms of the dose exposure rate from a safety assessment of the DBD is also presented and compared to the case of direct disposal of SFs in a KBS-3V vertical type repository, carried out in previous studies. For different types and shapes of repositories at each different depth, direct comparison between a DBD and a KBS-3 type disposal of

  11. Consolidated Deep Actor Critic Networks (DRAFT)

    NARCIS (Netherlands)

    Van der Laan, T.A.

    2015-01-01

    The works [Volodymyr et al. Playing atari with deep reinforcement learning. arXiv preprint arXiv:1312.5602, 2013.] and [Volodymyr et al. Human-level control through deep reinforcement learning. Nature, 518(7540):529–533, 2015.] have demonstrated the power of combining deep neural networks with

  12. Deep Galaxy: Classification of Galaxies based on Deep Convolutional Neural Networks

    OpenAIRE

    Khalifa, Nour Eldeen M.; Taha, Mohamed Hamed N.; Hassanien, Aboul Ella; Selim, I. M.

    2017-01-01

    In this paper, a deep convolutional neural network architecture for galaxies classification is presented. The galaxy can be classified based on its features into main three categories Elliptical, Spiral, and Irregular. The proposed deep galaxies architecture consists of 8 layers, one main convolutional layer for features extraction with 96 filters, followed by two principles fully connected layers for classification. It is trained over 1356 images and achieved 97.272% in testing accuracy. A c...

  13. Irradiation stratigraphy in the Apollo 16 deep drill section 60002

    Science.gov (United States)

    Blanford, G. E.; Wood, G. C.

    1978-01-01

    Particle track density frequency distributions, abundance of track rich grains and minimum track densities are reported for the upper 20 cm of the 60002 section of the Apollo 16 deep drill core. The principal stratigraphic feature is a boundary approximately 7 cm from the top of the section. Experimental evidence does not conclusively determine whether this contact is an ancient regolith surface or is simply a depositional boundary. If it is an ancient surface, it has a model exposure age of 3 to 7 million years and a reworking depth of about 0.5 cm. However, because track density frequency distributions indicate the mixing of soils of different maturities, we favor interpreting this contact as a depositional boundary. There may be a second depositional boundary approximately 19 cm below the top of 60002.

  14. Uncovering molecular relaxation processes with nonlinear spectroscopies in the deep UV

    International Nuclear Information System (INIS)

    West, Brantley A.; Molesky, Brian P.; Giokas, Paul G.; Moran, Andrew M.

    2013-01-01

    Highlights: • We discuss the outlook for multidimensional spectroscopies in the deep UV. • Photophysics are examined in small DNA components at cryogenic temperatures. • Wavepacket motions are detected in ring-opening systems with 2DUV spectroscopy. • Measurements of electronic wavepacket motions in molecules are proposed. - Abstract: Nonlinear laser spectroscopies in the deep UV spectral range are motivated by studies of biological systems and elementary processes in small molecules. This perspective article discusses recent technical advances in this area with a particular emphasis on diffractive optic based approaches to four-wave mixing spectroscopies. Applications to two classes of systems illustrate present experimental capabilities. First, experiments on DNA components at cryogenic temperatures are used to uncover features of excited state potential energy surfaces and vibrational cooling mechanisms. Second, sub-200 fs internal conversion processes and coherent wavepacket motions are investigated in cyclohexadiene and α-terpinene. Finally, we propose new experimental directions that combine methods for producing few-cycle UV laser pulses in noble gases with incoherent detection methods (e.g., photoionization) in experiments with time resolution near a singlefemtosecond. These measurements are motivated by knowledge of extremely fast non-adiabatic dynamics and the resolution of electronic wavepacket motions in molecules

  15. Deep Feature Consistent Variational Autoencoder

    OpenAIRE

    Hou, Xianxu; Shen, Linlin; Sun, Ke; Qiu, Guoping

    2016-01-01

    We present a novel method for constructing Variational Autoencoder (VAE). Instead of using pixel-by-pixel loss, we enforce deep feature consistency between the input and the output of a VAE, which ensures the VAE's output to preserve the spatial correlation characteristics of the input, thus leading the output to have a more natural visual appearance and better perceptual quality. Based on recent deep learning works such as style transfer, we employ a pre-trained deep convolutional neural net...

  16. Bimaximal fermion mixing from the quark and leptonic mixing matrices

    International Nuclear Information System (INIS)

    Ohlsson, Tommy

    2005-01-01

    In this Letter, we show how the mixing angles of the standard parameterization add when multiplying the quark and leptonic mixing matrices, i.e., we derive explicit sum rules for the quark and leptonic mixing angles. In this connection, we also discuss other recently proposed sum rules for the mixing angles assuming bimaximal fermion mixing. In addition, we find that the present experimental and phenomenological data of the mixing angles naturally fulfill our sum rules, and thus, give rise to bilarge or bimaximal fermion mixing

  17. A long history of equatorial deep-water upwelling in the Pacific Ocean

    Science.gov (United States)

    Zhang, Yi Ge; Pagani, Mark; Henderiks, Jorijntje; Ren, Haojia

    2017-06-01

    Cold, nutrient- and CO2-rich waters upwelling in the eastern equatorial Pacific (EEP) give rise to the Pacific cold tongue. Quasi-periodic subsidence of the thermocline and attenuation in wind strength expressed by El Niño conditions decrease upwelling rates, increase surface-water temperatures in the EEP, and lead to changes in regional climates both near and far from the equatorial Pacific. EEP surface waters have elevated CO2 concentrations during neutral (upwelling) or La Niña (strong upwelling) conditions. In contrast, approximate air-sea CO2 equilibrium characterizes El Niño events. One hypothesis proposes that changes in physical oceanography led to the establishment of a deep tropical thermocline and expanded mixed-layer prior to 3 million years ago. These effects are argued to have substantially reduced deep-water upwelling rates in the EEP and promoted a "permanent El Niño-like" climate state. For this study, we test this supposition by reconstructing EEP "excess CO2" and upwelling history for the past 6.5 million years using the alkenone-pCO2 methodology. Contrary to previous assertions, our results indicate that average temporal conditions in the EEP over the past ∼6.5 million years were characterized by substantial CO2 disequilibrium and high nutrient delivery to surface waters - characteristics that imply strong upwelling of deep waters. Upwelling appears most vigorous between ∼6.5 to 4.5 million years ago coinciding with high accumulation rates of biogenic material during the late Miocene - early Pliocene "biogenic bloom".

  18. WRF nested large-eddy simulations of deep convection during SEAC4RS

    Science.gov (United States)

    Heath, Nicholas K.; Fuelberg, Henry E.; Tanelli, Simone; Turk, F. Joseph; Lawson, R. Paul; Woods, Sarah; Freeman, Sean

    2017-04-01

    Large-eddy simulations (LES) and observations are often combined to increase our understanding and improve the simulation of deep convection. This study evaluates a nested LES method that uses the Weather Research and Forecasting (WRF) model and, specifically, tests whether the nested LES approach is useful for studying deep convection during a real-world case. The method was applied on 2 September 2013, a day of continental convection that occurred during the Studies of Emissions and Atmospheric Composition, Clouds and Climate Coupling by Regional Surveys (SEAC4RS) campaign. Mesoscale WRF output (1.35 km grid length) was used to drive a nested LES with 450 m grid spacing, which then drove a 150 m domain. Results reveal that the 450 m nested LES reasonably simulates observed reflectivity distributions and aircraft-observed in-cloud vertical velocities during the study period. However, when examining convective updrafts, reducing the grid spacing to 150 m worsened results. We find that the simulated updrafts in the 150 m run become too diluted by entrainment, thereby generating updrafts that are weaker than observed. Lastly, the 450 m simulation is combined with observations to study the processes forcing strong midlevel cloud/updraft edge downdrafts that were observed on 2 September. Results suggest that these strong downdrafts are forced by evaporative cooling due to mixing and by perturbation pressure forces acting to restore mass continuity around neighboring updrafts. We conclude that the WRF nested LES approach, with further development and evaluation, could potentially provide an effective method for studying deep convection in real-world cases.

  19. Recovery from deep-plane rhytidectomy following unilateral wound treatment with autologous platelet gel: a pilot study.

    Science.gov (United States)

    Powell, D M; Chang, E; Farrior, E H

    2001-01-01

    To determine the effects of treatment with autologous platelet-rich plasma mixed with thrombin and calcium chloride to form an autologous platelet gel (APG) on postoperative recovery from deep-plane rhytidectomy. A prospective, randomized, controlled pilot study. An accredited ambulatory facial plastic surgery center. Healthy volunteer women (N = 8) undergoing rhytidectomy. Unilateral autologous platelet-rich plasma wound treatment during standard deep-plane rhytidectomy. Staged postoperative facial photographs were graded in a blinded fashion by 3 facial plastic surgeon reviewers for postoperative ecchymosis and edema. Each facial side treated with APG that demonstrated less edema or ecchymosis than the non-APG-treated side was designated a positive response; otherwise, the response was equal (no difference) or negative (untreated side had less edema or ecchymosis). Twenty-one positive and 21 equal responses were observed compared with 8 negative ones. Of 20 unanimous observations, 15 were positive, only 3 equal, and 1 negative. Treatment with APG may prevent or improve edema or ecchymosis after deep-plane rhytidectomy. This trend is more apparent for ecchymosis than for edema, and is chiefly demonstrable in the early phases of recovery. These observations are consistent with previous reports of cell tissue culture and wound response to concentrated platelet product.

  20. CRIMSON [CRisis plan IMpact: Subjective and Objective coercion and eNgagement] Protocol: A randomised controlled trial of joint crisis plans to reduce compulsory treatment of people with psychosis

    Directory of Open Access Journals (Sweden)

    Henderson Claire

    2010-11-01

    Full Text Available Abstract Background The use of compulsory treatment under the Mental Health Act (MHA has continued to rise in the UK and in other countries. The Joint Crisis Plan (JCP is a statement of service users' wishes for treatment in the event of a future mental health crisis. It is developed with the clinical team and an independent facilitator. A recent pilot RCT showed a reduction in the use of the MHA amongst service users with a JCP. The JCP is the only intervention that has been shown to reduce compulsory treatment in this way. The CRIMSON trial aims to determine if JCPs, compared with treatment as usual, are effective in reducing the use of the MHA in a range of treatment settings across the UK. Methods/Design This is a 3 centre, individual-level, single-blind, randomised controlled trial of the JCP compared with treatment as usual for people with a history of relapsing psychotic illness in Birmingham, London and Lancashire/Manchester. 540 service users will be recruited across the three sites. Eligible service users will be adults with a diagnosis of a psychotic disorder (including bipolar disorder, treated in the community under the Care Programme Approach with at least one admission to a psychiatric inpatient ward in the previous two years. Current inpatients and those subject to a community treatment order will be excluded to avoid any potential perceived pressure to participate. Research assessments will be conducted at baseline and 18 months. Following the baseline assessment, eligible service users will be randomly allocated to either develop a Joint Crisis Plan or continue with treatment as usual. Outcome will be assessed at 18 months with assessors blind to treatment allocation. The primary outcome is the proportion of service users treated or otherwise detained under an order of the Mental Health Act (MHA during the follow-up period, compared across randomisation groups. Secondary outcomes include overall costs, service user engagement

  1. Property changes of deep and bottom waters in the Western Tropical Atlantic

    Science.gov (United States)

    Herrford, Josefine; Brandt, Peter; Zenk, Walter

    2017-06-01

    The flow of North Atlantic Deep Water (NADW) and Antarctic Bottom Water (AABW) contributes to the Atlantic meridional overturning circulation. Changes in the associated water mass formation might impact the deep ocean's capacity to take up anthropogenic CO2 while a warming of the deep ocean significantly contributes to global sea level rise. Here we compile historic and recent shipboard measurements of hydrography and velocity to provide a comprehensive view of water mass distribution, pathways, along-path transformation and long-term temperature changes of NADW and AABW in the western South and Equatorial Atlantic. We confirm previous results which show that the northwest corner of the Brazil Basin represents a splitting point for the southward/northward flow of NADW/AABW. The available measurements sample water mass transformation along the two major routes for deep and bottom waters in the tropical to South Atlantic - along the deep western boundary and eastward, parallel to the equator - as well as the hot-spots of extensive mixing. We find lower NADW and lighter AABW to form a highly interactive transition layer in the northern Brazil Basin. The AABW north of 5°S is relatively homogeneous with only lighter AABW being able to pass through the Equatorial Channel (EQCH) into the North Atlantic. Spanning a period of 26 years, our data also allow an estimation of long-term temperature trends in abyssal waters. We find a warming of 2.5±0.7•10-3 °C yr-1 of the waters in the northern Brazil Basin at temperatures colder than 0.6 °C throughout the period 1989-2014 and can relate this warming to a thinning of the dense AABW layer. Whereas isopycnal heave is the dominant effect which defines the vertical distribution of temperature trends on isobars, we also find temperature changes on isopycnals in the lower NADW and AABW layers. There temperatures on isopycnals exhibit decadal variations with warming in the 1990s and cooling in the 2000s - the contributions to the

  2. Aggressive Behavior as a Predictor of Self-Concept: A Study with a Sample of Spanish Compulsory Secondary Education Students

    Directory of Open Access Journals (Sweden)

    María S. Torregrosa

    2011-07-01

    Full Text Available This study analyzed the relationship between aggressive behavior and self-concept in a sample of 2,022 Spanish students (51.09% males of Compulsory Secondary Education, ranging in age from 12 to 16 years. Aggressive behavior was assessed using the Teenage Inventory of Social Skills (TISS, and selfconcept was assessed with the Self-Description Questionnaire II (SDQ-II. Logistic regression analyses showed that adolescents with aggressive behavior were more likely to perceive their relationship with their parents as negative, show little interest in verbal activities, be less sincere, and have lower self-esteem than their non-aggressive peers. Furthermore, despite models varied according to sex and grade, in most cases adolescents with high aggressive behavior also showed a higher probability of perceiving their relation with peers of the same sex in a negative way, being less interested in school domains and showing higher emotional instability than their non-aggressive counterparts. Non-expected results were obtained regarding the perceptions about interactions with peers of the opposite sex and physical appearance. Results are discussed attending to their practical implications.

  3. How Stressful Is "Deep Bubbling"?

    Science.gov (United States)

    Tyrmi, Jaana; Laukkanen, Anne-Maria

    2017-03-01

    Water resistance therapy by phonating through a tube into the water is used to treat dysphonia. Deep submersion (≥10 cm in water, "deep bubbling") is used for hypofunctional voice disorders. Using it with caution is recommended to avoid vocal overloading. This experimental study aimed to investigate how strenuous "deep bubbling" is. Fourteen subjects, half of them with voice training, repeated the syllable [pa:] in comfortable speaking pitch and loudness, loudly, and in strained voice. Thereafter, they phonated a vowel-like sound both in comfortable loudness and loudly into a glass resonance tube immersed 10 cm into the water. Oral pressure, contact quotient (CQ, calculated from electroglottographic signal), and sound pressure level were studied. The peak oral pressure P(oral) during [p] and shuttering of the outer end of the tube was measured to estimate the subglottic pressure P(sub) and the mean P(oral) during vowel portions to enable calculation of transglottic pressure P(trans). Sensations during phonation were reported with an open-ended interview. P(sub) and P(oral) were higher in "deep bubbling" and P(trans) lower than in loud syllable phonation, but the CQ did not differ significantly. Similar results were obtained for the comparison between loud "deep bubbling" and strained phonation, although P(sub) did not differ significantly. Most of the subjects reported "deep bubbling" to be stressful only for respiratory and lip muscles. No big differences were found between trained and untrained subjects. The CQ values suggest that "deep bubbling" may increase vocal fold loading. Further studies should address impact stress during water resistance exercises. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  4. Evaluation of the DeepWind concept

    DEFF Research Database (Denmark)

    Schmidt Paulsen, Uwe; Borg, Michael; Gonzales Seabra, Luis Alberto

    The report describes the DeepWind 5 MW conceptual design as a baseline for results obtained in the scientific and technical work packages of the DeepWind project. A comparison of DeepWi nd with existing VAWTs and paper projects are carried out and the evaluation of the concept in terms of cost...

  5. Simulator Studies of the Deep Stall

    Science.gov (United States)

    White, Maurice D.; Cooper, George E.

    1965-01-01

    Simulator studies of the deep-stall problem encountered with modern airplanes are discussed. The results indicate that the basic deep-stall tendencies produced by aerodynamic characteristics are augmented by operational considerations. Because of control difficulties to be anticipated in the deep stall, it is desirable that adequate safeguards be provided against inadvertent penetrations.

  6. Research on the neutron flux, secular equilibrium of chlorine-36 and groundwater age of the deep quaternary sediments, Hebei plain

    International Nuclear Information System (INIS)

    Dong Yuean; He Ming; Jiang Songsheng; Wu Shaoyong; Jiang Shan

    2001-01-01

    For the study of the neutron flux, secular equilibrium of chlorine-36 in the deep quaternary sediments of Hebei plain, the main chemical composition of water sand and confining bed was determined by neutron activation analysis. The mean neutron flux is 2.79 x 10 -5 cm -2 s -1 which was calculated by the chemical composition of the strata. The mean 36 Cl/Cl ratio in secular equilibrium is 1.27 x 10 -14 in the deep quaternary sediments, Hebei Plain. For the study of the groundwater age of the deep Quaternary sediments of Hebei Plain, the 36 Cl/Cl ratio of groundwater samples were determined by tandem accelerator mass spectrometry. The mixed groundwater 36 Cl/Cl ratio of the second and the third aquifer of Quaternary sediments in Baoding district is 247 x 10 -15 , that of the fourth aquifer in Baoding city is 224 x 10 -15 and the third aquifer in Cangzhou district is 40.5 x 10 -15 . The groundwater age of Baoding district was young and that of the third aquifer in Cangzhou was 229.2 ka

  7. Deep Learning

    DEFF Research Database (Denmark)

    Jensen, Morten Bornø; Bahnsen, Chris Holmberg; Nasrollahi, Kamal

    2018-01-01

    I løbet af de sidste 10 år er kunstige neurale netværk gået fra at være en støvet, udstødt tekno-logi til at spille en hovedrolle i udviklingen af kunstig intelligens. Dette fænomen kaldes deep learning og er inspireret af hjernens opbygning.......I løbet af de sidste 10 år er kunstige neurale netværk gået fra at være en støvet, udstødt tekno-logi til at spille en hovedrolle i udviklingen af kunstig intelligens. Dette fænomen kaldes deep learning og er inspireret af hjernens opbygning....

  8. Modification of Co-Mn-Al Mixed Oxide with Potassium and Its Effect on Deep Oxidation of VOC

    Czech Academy of Sciences Publication Activity Database

    Jirátová, Květa; Mikulová, Jana; Klempa, Jan; Grygar, Tomáš; Bastl, Zdeněk; Kovanda, F.

    2009-01-01

    Roč. 361, 1-2 (2009), s. 106-116 ISSN 0926-860X R&D Projects: GA ČR GA104/07/1400 Institutional research plan: CEZ:AV0Z40720504; CEZ:AV0Z40320502; CEZ:AV0Z40400503 Keywords : mixed oxide catalysts * VOC total oxidation * potassium promoter Subject RIV: CC - Organic Chemistry Impact factor: 3.564, year: 2009

  9. Deep-Earth Equilibration between Molten Iron and Solid Silicates

    Science.gov (United States)

    Brennan, M.; Zurkowski, C. C.; Chidester, B.; Campbell, A.

    2017-12-01

    Elemental partitioning between iron-rich metals and silicate minerals influences the properties of Earth's deep interior, and is ultimately responsible for the nature of the core-mantle boundary. These interactions between molten iron and solid silicates were influential during planetary accretion, and persist today between the mantle and liquid outer core. Here we report the results of diamond anvil cell experiments at lower mantle conditions (40 GPa, >2500 K) aimed at examining systems containing a mixture of metals (iron or Fe-16Si alloy) and silicates (peridotite). The experiments were conducted at pressure-temperature conditions above the metallic liquidus but below the silicate solidus, and the recovered samples were analyzed by FIB/SEM with EDS to record the compositions of the coexisting phases. Each sample formed a three-phase equilibrium between bridgmanite, Fe-rich metallic melt, and an oxide. In one experiment, using pure Fe, the quenched metal contained 6 weight percent O, and the coexisting oxide was ferropericlase. The second experiment, using Fe-Si alloy, was highly reducing; its metal contained 10 wt% Si, and the coexisting mineral was stishovite. The distinct mineralogies of the two experiments derived from their different starting metals. These results imply that metallic composition is an important factor in determining the products of mixed phase iron-silicate reactions. The properties of deep-Earth interfaces such as the core-mantle boundary could be strongly affected by their metallic components.

  10. Mixing regime of the residual water basins of the Aral Sea

    Science.gov (United States)

    Izhitskiy, Alexander; Zavialov, Peter; Kirillin, Georgiy

    2017-04-01

    The Aral Sea, a terminal salt lake in western Central Asia situated at the border between Uzbekistan and Kazakhstan, was ranked as the fourth largest inland water body in the mid-20th century. However, in the early 1960s, the lake's volume started to decrease rapidly due to severe changes in the Aral's water balance. Thus, the present-day Aral Sea can be considered as a system of separate water bodies with a common origin but very different physical, chemical and biological features. Our previous studies showed that the Large Aral Sea and Lake Tshchebas transformed into hyperhaline water bodies, while the Small Aral Sea was a brackish basin with rather similar to the pre-desiccation environment. On the other hand, the Small Aral Sea and Lake Tshchebas exhibited a mixed vertical structure, whereas the Western Large Aral Sea (especially the Chernyshev Bay) was strongly stratified. The presented study is focused on the seasonal mixing regimes of the residual basins. Isolation of deep waters from the atmosphere together with low rates of photosynthesis produce deep anoxia observed in the Chernyshev Bay and in the Large Aral. The high amount of organic matter provides a rich source of nutrients for anoxic microorganisms favoring methanogenesis in the bottom layer of the basins. In the Small Aral, the water column remains well-oxygenated down to the bottom throughout most of the year and development of anoxia is unlikely. The mixing regimes of the recently formed residual lakes of the former Aral Sea will provide manifold effect on the ongoing development of the aquatic system in the following decades. The study is based on a field data collected during two surveys of Shirshov Institute of Oceanology to the Aral Sea, which took place in October, 2015 and June, 2016. In situ measurements including CTD profiling and water sampling were carried out in the northern extremity of the western Large Aral (the Chernyshev Bay), in Lake Tshchebas, and in the Small Aral Sea

  11. The effect of aerosol-derived changes in the warm phase on the properties of deep convective clouds

    Science.gov (United States)

    Chen, Qian; Koren, Ilan; Altaratz, Orit; Heiblum, Reuven; Dagan, Guy

    2017-04-01

    The aerosol impact on deep convective clouds starts in an increased number of cloud droplets in higher aerosol loading environment. This change drives many others, like enhanced condensational growth, delay in collision-coalescence and others. Since the warm processes serve as the initial and boundary conditions for the mixed and cold-phase processes in deep clouds, it is highly important to understand the aerosol effect on them. The weather research and forecasting model (WRF) with spectral bin microphysics was used to study a deep convective system over the Marshall Islands, during the Kwajalein Experiment (KWAJEX). Three simulations were conducted with aerosol concentrations of 100, 500 and 2000 cm-3, to reflect clean, semipolluted, and polluted conditions. The results of the clean run agreed well with the radar profiles and rain rate observations. The more polluted simulations resulted in larger total cloud mass, larger upper level cloud fraction and rain rates. There was an increased mass both below and above the zero temperature level. It indicates of more efficient growth processes both below and above the zero level. In addition the polluted runs showed an increased upward transport (across the zero level) of liquid water due to both stronger updrafts and larger droplet mobility. In this work we discuss the transport of cloud mass crossing the zero temperature level (in both directions) in order to gain a process level understanding of how aerosol effects on the warm processes affect the macro- and micro-properties of deep convective clouds.

  12. Exploring the isopycnal mixing and helium–heat paradoxes in a suite of Earth system models

    Directory of Open Access Journals (Sweden)

    A. Gnanadesikan

    2015-07-01

    this paper we show that this is not the case. In a suite of models with different spatially constant and spatially varying values of ARedi the distribution of radiocarbon and helium isotopes is sensitive to the value of ARedi. However, away from strong helium sources in the southeastern Pacific, the relationship between the two is not sensitive, indicating that large-scale advection is the limiting process for removing helium and radiocarbon from the deep ocean. The helium isotopes, in turn, suggest a higher value of ARedi below the thermocline than is seen in theoretical parameterizations based on baroclinic growth rates. We argue that a key part of resolving the isopycnal mixing paradox is to abandon the idea that ARedi has a direct relationship to local baroclinic instability and to the so-called "thickness" mixing coefficient AGM.

  13. European mixed forests

    DEFF Research Database (Denmark)

    Bravo-Oviedo, Andres; Pretzsch, Hans; Ammer, Christian

    2014-01-01

    Aim of study: We aim at (i) developing a reference definition of mixed forests in order to harmonize comparative research in mixed forests and (ii) review the research perspectives in mixed forests. Area of study: The definition is developed in Europe but can be tested worldwide. Material...... and Methods: Review of existent definitions of mixed forests based and literature review encompassing dynamics, management and economic valuation of mixed forests. Main results: A mixed forest is defined as a forest unit, excluding linear formations, where at least two tree species coexist at any...... density in mixed forests, (iii) conversion of monocultures to mixed-species forest and (iv) economic valuation of ecosystem services provided by mixed forests. Research highlights: The definition is considered a high-level one which encompasses previous attempts to define mixed forests. Current fields...

  14. DeepNAT: Deep convolutional neural network for segmenting neuroanatomy.

    Science.gov (United States)

    Wachinger, Christian; Reuter, Martin; Klein, Tassilo

    2018-04-15

    We introduce DeepNAT, a 3D Deep convolutional neural network for the automatic segmentation of NeuroAnaTomy in T1-weighted magnetic resonance images. DeepNAT is an end-to-end learning-based approach to brain segmentation that jointly learns an abstract feature representation and a multi-class classification. We propose a 3D patch-based approach, where we do not only predict the center voxel of the patch but also neighbors, which is formulated as multi-task learning. To address a class imbalance problem, we arrange two networks hierarchically, where the first one separates foreground from background, and the second one identifies 25 brain structures on the foreground. Since patches lack spatial context, we augment them with coordinates. To this end, we introduce a novel intrinsic parameterization of the brain volume, formed by eigenfunctions of the Laplace-Beltrami operator. As network architecture, we use three convolutional layers with pooling, batch normalization, and non-linearities, followed by fully connected layers with dropout. The final segmentation is inferred from the probabilistic output of the network with a 3D fully connected conditional random field, which ensures label agreement between close voxels. The roughly 2.7million parameters in the network are learned with stochastic gradient descent. Our results show that DeepNAT compares favorably to state-of-the-art methods. Finally, the purely learning-based method may have a high potential for the adaptation to young, old, or diseased brains by fine-tuning the pre-trained network with a small training sample on the target application, where the availability of larger datasets with manual annotations may boost the overall segmentation accuracy in the future. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Deep Learning and Its Applications in Biomedicine.

    Science.gov (United States)

    Cao, Chensi; Liu, Feng; Tan, Hai; Song, Deshou; Shu, Wenjie; Li, Weizhong; Zhou, Yiming; Bo, Xiaochen; Xie, Zhi

    2018-02-01

    Advances in biological and medical technologies have been providing us explosive volumes of biological and physiological data, such as medical images, electroencephalography, genomic and protein sequences. Learning from these data facilitates the understanding of human health and disease. Developed from artificial neural networks, deep learning-based algorithms show great promise in extracting features and learning patterns from complex data. The aim of this paper is to provide an overview of deep learning techniques and some of the state-of-the-art applications in the biomedical field. We first introduce the development of artificial neural network and deep learning. We then describe two main components of deep learning, i.e., deep learning architectures and model optimization. Subsequently, some examples are demonstrated for deep learning applications, including medical image classification, genomic sequence analysis, as well as protein structure classification and prediction. Finally, we offer our perspectives for the future directions in the field of deep learning. Copyright © 2018. Production and hosting by Elsevier B.V.

  16. Deep Water Acoustics

    Science.gov (United States)

    2016-06-28

    the Deep Water project and participate in the NPAL Workshops, including Art Baggeroer (MIT), J. Beron- Vera (UMiami), M. Brown (UMiami), T...Kathleen E . Wage. The North Pacific Acoustic Laboratory deep-water acoustic propagation experiments in the Philippine Sea. J. Acoust. Soc. Am., 134(4...estimate of the angle α during PhilSea09, made from ADCP measurements at the site of the DVLA. Sim. A B1 B2 B3 C D E F Prof. # 0 4 4 4 5 10 16 20 α

  17. Mixing driven by transient buoyancy flows. I. Kinematics

    Science.gov (United States)

    Duval, W. M. B.; Zhong, H.; Batur, C.

    2018-05-01

    Mixing of two miscible liquids juxtaposed inside a cavity initially separated by a divider, whose buoyancy-driven motion is initiated via impulsive perturbation of divider motion that can generate the Richtmyer-Meshkov instability, is investigated experimentally. The measured Lagrangian history of interface motion that contains the continuum mechanics of mixing shows self-similar nearly Gaussian length stretch distribution for a wide range of control parameters encompassing an approximate Hele-Shaw cell to a three-dimensional cavity. Because of the initial configuration of the interface which is parallel to the gravitational field, we show that at critical initial potential energy mixing occurs through the stretching of the interface, which shows frontogenesis, and folding, owing to an overturning motion that results in unstable density stratification and produces an ideal condition for the growth of the single wavelength Rayleigh-Taylor instability. The initial perturbation of the interface and flow field generates the Kelvin-Helmholtz instability and causes kinks at the interface, which grow into deep fingers during overturning motion and unfold into local whorl structures that merge and self-organize into the Rayleigh-Taylor morphology (RTM) structure. For a range of parametric space that yields two-dimensional flows, the unfolding of the instability through a supercritical bifurcation yields an asymmetric pairwise structure exhibiting smooth RTM that transitions to RTM fronts with fractal structures that contain small length scales for increasing Peclet numbers. The late stage of the RTM structure unfolds into an internal breakwave that breaks down through wall and internal collision and sets up the condition for self-induced sloshing that decays exponentially as the two fluids become stably stratified with a diffusive region indicating local molecular diffusion.

  18. Active Microbial Communities Inhabit Sulphate-Methane Interphase in Deep Bedrock Fracture Fluids in Olkiluoto, Finland

    Directory of Open Access Journals (Sweden)

    Malin Bomberg

    2015-01-01

    Full Text Available Active microbial communities of deep crystalline bedrock fracture water were investigated from seven different boreholes in Olkiluoto (Western Finland using bacterial and archaeal 16S rRNA, dsrB, and mcrA gene transcript targeted 454 pyrosequencing. Over a depth range of 296–798 m below ground surface the microbial communities changed according to depth, salinity gradient, and sulphate and methane concentrations. The highest bacterial diversity was observed in the sulphate-methane mixing zone (SMMZ at 250–350 m depth, whereas archaeal diversity was highest in the lowest boundaries of the SMMZ. Sulphide-oxidizing ε-proteobacteria (Sulfurimonas sp. dominated in the SMMZ and γ-proteobacteria (Pseudomonas spp. below the SMMZ. The active archaeal communities consisted mostly of ANME-2D and Thermoplasmatales groups, although Methermicoccaceae, Methanobacteriaceae, and Thermoplasmatales (SAGMEG, TMG were more common at 415–559 m depth. Typical indicator microorganisms for sulphate-methane transition zones in marine sediments, such as ANME-1 archaea, α-, β- and δ-proteobacteria, JS1, Actinomycetes, Planctomycetes, Chloroflexi, and MBGB Crenarchaeota were detected at specific depths. DsrB genes were most numerous and most actively transcribed in the SMMZ while the mcrA gene concentration was highest in the deep methane rich groundwater. Our results demonstrate that active and highly diverse but sparse and stratified microbial communities inhabit the Fennoscandian deep bedrock ecosystems.

  19. Seasonality of Red Sea Mixed-Layer Depth and Density Budget

    Science.gov (United States)

    Kartadikaria, A. R.; Cerovecki, I.; Krokos, G.; Hoteit, I.

    2016-02-01

    The Red Sea is an active area of water mass formation. Dense water initially formed in the northern Red Sea, in the Gulf of Aqaba and the Gulf of Suez, spreads southward and finally flows to the open ocean through the Gulf of Aden via the narrow strait of Bab Al Mandeb. The signature of this outflow can be traced until the southern Indian Ocean, and is characterized by potential density of σθ ≈ 27.4. This water mass is important because it represents a significant source of heat and salt for the Indian Ocean. Using a high-resolution 1km regional MITgcm ocean model for the period 1992-2001 configured for the Red Sea, we examine the spatio-temporal characteristics of water mass formation inside the basin by analyzing closed and complete temperature and salinity budgets. The deepest mixed-layers (MLD) always develop in the northern part of the basin where surface ocean buoyancy loss leads to the Red Sea Intermediate and Deep Water formation. As this water is advected south, it is strongly modified by diapycnal mixing of heat and salt.

  20. Overview of deep learning in medical imaging.

    Science.gov (United States)

    Suzuki, Kenji

    2017-09-01

    The use of machine learning (ML) has been increasing rapidly in the medical imaging field, including computer-aided diagnosis (CAD), radiomics, and medical image analysis. Recently, an ML area called deep learning emerged in the computer vision field and became very popular in many fields. It started from an event in late 2012, when a deep-learning approach based on a convolutional neural network (CNN) won an overwhelming victory in the best-known worldwide computer vision competition, ImageNet Classification. Since then, researchers in virtually all fields, including medical imaging, have started actively participating in the explosively growing field of deep learning. In this paper, the area of deep learning in medical imaging is overviewed, including (1) what was changed in machine learning before and after the introduction of deep learning, (2) what is the source of the power of deep learning, (3) two major deep-learning models: a massive-training artificial neural network (MTANN) and a convolutional neural network (CNN), (4) similarities and differences between the two models, and (5) their applications to medical imaging. This review shows that ML with feature input (or feature-based ML) was dominant before the introduction of deep learning, and that the major and essential difference between ML before and after deep learning is the learning of image data directly without object segmentation or feature extraction; thus, it is the source of the power of deep learning, although the depth of the model is an important attribute. The class of ML with image input (or image-based ML) including deep learning has a long history, but recently gained popularity due to the use of the new terminology, deep learning. There are two major models in this class of ML in medical imaging, MTANN and CNN, which have similarities as well as several differences. In our experience, MTANNs were substantially more efficient in their development, had a higher performance, and required a

  1. WFIRST: Science from Deep Field Surveys

    Science.gov (United States)

    Koekemoer, Anton; Foley, Ryan; WFIRST Deep Field Working Group

    2018-01-01

    WFIRST will enable deep field imaging across much larger areas than those previously obtained with Hubble, opening up completely new areas of parameter space for extragalactic deep fields including cosmology, supernova and galaxy evolution science. The instantaneous field of view of the Wide Field Instrument (WFI) is about 0.3 square degrees, which would for example yield an Ultra Deep Field (UDF) reaching similar depths at visible and near-infrared wavelengths to that obtained with Hubble, over an area about 100-200 times larger, for a comparable investment in time. Moreover, wider fields on scales of 10-20 square degrees could achieve depths comparable to large HST surveys at medium depths such as GOODS and CANDELS, and would enable multi-epoch supernova science that could be matched in area to LSST Deep Drilling fields or other large survey areas. Such fields may benefit from being placed on locations in the sky that have ancillary multi-band imaging or spectroscopy from other facilities, from the ground or in space. The WFIRST Deep Fields Working Group has been examining the science considerations for various types of deep fields that may be obtained with WFIRST, and present here a summary of the various properties of different locations in the sky that may be considered for future deep fields with WFIRST.

  2. The Role of Complex Treatment in Mixed Leg Ulcers - A Case Report of Vascular, Surgical and Physical Therapy.

    Science.gov (United States)

    Wollina, Uwe; Heinig, Birgit; Stelzner, Christian; Hansel, Gesina; Schönlebe, Jacqueline; Tchernev, Georgi; Lotti, Torello

    2018-01-25

    Leg ulcers are a burden to patients, their families and society. The second most common cause of chronic leg ulcers is the mixed arterio-venous type. An 80-year-old female patient presented to our department due to painful enlarging chronic leg ulcer of mixed arteriovenous origin on her left lower leg. She suffered from peripheral arterial occlusive disease stage I and chronic venous insufficiency Widmer grade IIIa, and a number of comorbidities. The aim of our ulcer treatment was a complete and stable wound closure that was hampered by arterial occlusion, exposed tendon, and renal insiffuciency. To improve the prognosis for ulcer surgery, we performed percutaneous transluminal angioplasty, transcutaneous CO 2 and deep ulcer shaving. The wound was closed by sandwich transplantation using elastin-collagen dermal template and meshed split skin graft. She had a 100% graft take with rapid reduction of severe wound pain. Complex approaches are necessary, to gain optimum results in leg ulcer therapy in mixed leg ulcers. Therapeutic nihilism should be abandonend.

  3. TOPIC MODELING: CLUSTERING OF DEEP WEBPAGES

    OpenAIRE

    Muhunthaadithya C; Rohit J.V; Sadhana Kesavan; E. Sivasankar

    2015-01-01

    The internet is comprised of massive amount of information in the form of zillions of web pages.This information can be categorized into the surface web and the deep web. The existing search engines can effectively make use of surface web information.But the deep web remains unexploited yet. Machine learning techniques have been commonly employed to access deep web content.

  4. DeepSimulator: a deep simulator for Nanopore sequencing

    KAUST Repository

    Li, Yu; Han, Renmin; Bi, Chongwei; Li, Mo; Wang, Sheng; Gao, Xin

    2017-01-01

    or assembled contigs, we simulate the electrical current signals by a context-dependent deep learning model, followed by a base-calling procedure to yield simulated reads. This workflow mimics the sequencing procedure more naturally. The thorough experiments

  5. Building Program Vector Representations for Deep Learning

    OpenAIRE

    Mou, Lili; Li, Ge; Liu, Yuxuan; Peng, Hao; Jin, Zhi; Xu, Yan; Zhang, Lu

    2014-01-01

    Deep learning has made significant breakthroughs in various fields of artificial intelligence. Advantages of deep learning include the ability to capture highly complicated features, weak involvement of human engineering, etc. However, it is still virtually impossible to use deep learning to analyze programs since deep architectures cannot be trained effectively with pure back propagation. In this pioneering paper, we propose the "coding criterion" to build program vector representations, whi...

  6. [Deep vein thrombosis prophylaxis.

    Science.gov (United States)

    Sandoval-Chagoya, Gloria Alejandra; Laniado-Laborín, Rafael

    2013-01-01

    Background: despite the proven effectiveness of preventive therapy for deep vein thrombosis, a significant proportion of patients at risk for thromboembolism do not receive prophylaxis during hospitalization. Our objective was to determine the adherence to thrombosis prophylaxis guidelines in a general hospital as a quality control strategy. Methods: a random audit of clinical charts was conducted at the Tijuana General Hospital, Baja California, Mexico, to determine the degree of adherence to deep vein thrombosis prophylaxis guidelines. The instrument used was the Caprini's checklist for thrombosis risk assessment in adult patients. Results: the sample included 300 patient charts; 182 (60.7 %) were surgical patients and 118 were medical patients. Forty six patients (15.3 %) received deep vein thrombosis pharmacologic prophylaxis; 27.1 % of medical patients received deep vein thrombosis prophylaxis versus 8.3 % of surgical patients (p < 0.0001). Conclusions: our results show that adherence to DVT prophylaxis at our hospital is extremely low. Only 15.3 % of our patients at risk received treatment, and even patients with very high risk received treatment in less than 25 % of the cases. We have implemented strategies to increase compliance with clinical guidelines.

  7. Contemporary deep recurrent learning for recognition

    Science.gov (United States)

    Iftekharuddin, K. M.; Alam, M.; Vidyaratne, L.

    2017-05-01

    Large-scale feed-forward neural networks have seen intense application in many computer vision problems. However, these networks can get hefty and computationally intensive with increasing complexity of the task. Our work, for the first time in literature, introduces a Cellular Simultaneous Recurrent Network (CSRN) based hierarchical neural network for object detection. CSRN has shown to be more effective to solving complex tasks such as maze traversal and image processing when compared to generic feed forward networks. While deep neural networks (DNN) have exhibited excellent performance in object detection and recognition, such hierarchical structure has largely been absent in neural networks with recurrency. Further, our work introduces deep hierarchy in SRN for object recognition. The simultaneous recurrency results in an unfolding effect of the SRN through time, potentially enabling the design of an arbitrarily deep network. This paper shows experiments using face, facial expression and character recognition tasks using novel deep recurrent model and compares recognition performance with that of generic deep feed forward model. Finally, we demonstrate the flexibility of incorporating our proposed deep SRN based recognition framework in a humanoid robotic platform called NAO.

  8. Mixing it but not mixed-up: mixed methods research in medical education (a critical narrative review).

    Science.gov (United States)

    Maudsley, Gillian

    2011-01-01

    Some important research questions in medical education and health services research need 'mixed methods research' (particularly synthesizing quantitative and qualitative findings). The approach is not new, but should be more explicitly reported. The broad search question here, of a disjointed literature, was thus: What is mixed methods research - how should it relate to medical education research?, focused on explicit acknowledgement of 'mixing'. Literature searching focused on Web of Knowledge supplemented by other databases across disciplines. Five main messages emerged: - Thinking quantitative and qualitative, not quantitative versus qualitative - Appreciating that mixed methods research blends different knowledge claims, enquiry strategies, and methods - Using a 'horses for courses' [whatever works] approach to the question, and clarifying the mix - Appreciating how medical education research competes with the 'evidence-based' movement, health services research, and the 'RCT' - Being more explicit about the role of mixed methods in medical education research, and the required expertise Mixed methods research is valuable, yet the literature relevant to medical education is fragmented and poorly indexed. The required time, effort, expertise, and techniques deserve better recognition. More write-ups should explicitly discuss the 'mixing' (particularly of findings), rather than report separate components.

  9. Towards deep learning with segregated dendrites.

    Science.gov (United States)

    Guerguiev, Jordan; Lillicrap, Timothy P; Richards, Blake A

    2017-12-05

    Deep learning has led to significant advances in artificial intelligence, in part, by adopting strategies motivated by neurophysiology. However, it is unclear whether deep learning could occur in the real brain. Here, we show that a deep learning algorithm that utilizes multi-compartment neurons might help us to understand how the neocortex optimizes cost functions. Like neocortical pyramidal neurons, neurons in our model receive sensory information and higher-order feedback in electrotonically segregated compartments. Thanks to this segregation, neurons in different layers of the network can coordinate synaptic weight updates. As a result, the network learns to categorize images better than a single layer network. Furthermore, we show that our algorithm takes advantage of multilayer architectures to identify useful higher-order representations-the hallmark of deep learning. This work demonstrates that deep learning can be achieved using segregated dendritic compartments, which may help to explain the morphology of neocortical pyramidal neurons.

  10. The deep ocean under climate change

    Science.gov (United States)

    Levin, Lisa A.; Le Bris, Nadine

    2015-11-01

    The deep ocean absorbs vast amounts of heat and carbon dioxide, providing a critical buffer to climate change but exposing vulnerable ecosystems to combined stresses of warming, ocean acidification, deoxygenation, and altered food inputs. Resulting changes may threaten biodiversity and compromise key ocean services that maintain a healthy planet and human livelihoods. There exist large gaps in understanding of the physical and ecological feedbacks that will occur. Explicit recognition of deep-ocean climate mitigation and inclusion in adaptation planning by the United Nations Framework Convention on Climate Change (UNFCCC) could help to expand deep-ocean research and observation and to protect the integrity and functions of deep-ocean ecosystems.

  11. NATURAL GAS RESOURCES IN DEEP SEDIMENTARY BASINS

    Energy Technology Data Exchange (ETDEWEB)

    Thaddeus S. Dyman; Troy Cook; Robert A. Crovelli; Allison A. Henry; Timothy C. Hester; Ronald C. Johnson; Michael D. Lewan; Vito F. Nuccio; James W. Schmoker; Dennis B. Riggin; Christopher J. Schenk

    2002-02-05

    From a geological perspective, deep natural gas resources are generally defined as resources occurring in reservoirs at or below 15,000 feet, whereas ultra-deep gas occurs below 25,000 feet. From an operational point of view, ''deep'' is often thought of in a relative sense based on the geologic and engineering knowledge of gas (and oil) resources in a particular area. Deep gas can be found in either conventionally-trapped or unconventional basin-center accumulations that are essentially large single fields having spatial dimensions often exceeding those of conventional fields. Exploration for deep conventional and unconventional basin-center natural gas resources deserves special attention because these resources are widespread and occur in diverse geologic environments. In 1995, the U.S. Geological Survey estimated that 939 TCF of technically recoverable natural gas remained to be discovered or was part of reserve appreciation from known fields in the onshore areas and State waters of the United. Of this USGS resource, nearly 114 trillion cubic feet (Tcf) of technically-recoverable gas remains to be discovered from deep sedimentary basins. Worldwide estimates of deep gas are also high. The U.S. Geological Survey World Petroleum Assessment 2000 Project recently estimated a world mean undiscovered conventional gas resource outside the U.S. of 844 Tcf below 4.5 km (about 15,000 feet). Less is known about the origins of deep gas than about the origins of gas at shallower depths because fewer wells have been drilled into the deeper portions of many basins. Some of the many factors contributing to the origin of deep gas include the thermal stability of methane, the role of water and non-hydrocarbon gases in natural gas generation, porosity loss with increasing thermal maturity, the kinetics of deep gas generation, thermal cracking of oil to gas, and source rock potential based on thermal maturity and kerogen type. Recent experimental simulations

  12. Deep smarts.

    Science.gov (United States)

    Leonard, Dorothy; Swap, Walter

    2004-09-01

    When a person sizes up a complex situation and rapidly comes to a decision that proves to be not just good but brilliant, you think, "That was smart." After you watch him do this a few times, you realize you're in the presence of something special. It's not raw brainpower, though that helps. It's not emotional intelligence, either, though that, too, is often involved. It's deep smarts. Deep smarts are not philosophical--they're not"wisdom" in that sense, but they're as close to wisdom as business gets. You see them in the manager who understands when and how to move into a new international market, in the executive who knows just what kind of talk to give when her organization is in crisis, in the technician who can track a product failure back to an interaction between independently produced elements. These are people whose knowledge would be hard to purchase on the open market. Their insight is based on know-how more than on know-what; it comprises a system view as well as expertise in individual areas. Because deep smarts are experienced based and often context specific, they can't be produced overnight or readily imported into an organization. It takes years for an individual to develop them--and no time at all for an organization to lose them when a valued veteran walks out the door. They can be taught, however, with the right techniques. Drawing on their forthcoming book Deep Smarts, Dorothy Leonard and Walter Swap say the best way to transfer such expertise to novices--and, on a larger scale, to make individual knowledge institutional--isn't through PowerPoint slides, a Web site of best practices, online training, project reports, or lectures. Rather, the sage needs to teach the neophyte individually how to draw wisdom from experience. Companies have to be willing to dedicate time and effort to such extensive training, but the investment more than pays for itself.

  13. Deep Learning and Developmental Learning: Emergence of Fine-to-Coarse Conceptual Categories at Layers of Deep Belief Network.

    Science.gov (United States)

    Sadeghi, Zahra

    2016-09-01

    In this paper, I investigate conceptual categories derived from developmental processing in a deep neural network. The similarity matrices of deep representation at each layer of neural network are computed and compared with their raw representation. While the clusters generated by raw representation stand at the basic level of abstraction, conceptual categories obtained from deep representation shows a bottom-up transition procedure. Results demonstrate a developmental course of learning from specific to general level of abstraction through learned layers of representations in a deep belief network. © The Author(s) 2016.

  14. Emplacement of zero-valent metal for remediation of deep contaminant plumes

    International Nuclear Information System (INIS)

    Hubble, D.W.; Gillham, R.W.; Cherry, J.A.

    1997-01-01

    Some groundwater plumes containing chlorinated solvent contaminants are found to be so deep that current in situ remediation technologies cannot be economically applied. Also, source zones are often found to be too deep for removal or inaccessible due to surface features. Plumes emanating from these sources require containment or treatment. Containment technologies are available for shallow sites (< 15 m) and are being developed for greater depths. However, it is important to advance the science of reactive treatment - both for cut off of plumes and to contain and treat source zones. Zero-valent metal technology has been used for remediation of solvent plumes at sites in Canada, the UK and at several industrial and military sites in the USA. To date, all of the plumes treated with zero-valent metal (granular iron) have been at depths less than 15 m. This paper gives preliminary results of research into methods to emplace granular iron at depths in the range of 15 to 60 m. The study included review of available and emerging methods of installing barrier or reactive material and the selection, preliminary design and costing of several methods. The design of a treatment system for a 122 m wide PCE plume that, immediately down gradient from its source, extends from a depth of 24 to 37 m below the ground surface is used as a demonstration site. Both Permeable Reactive Wall and Funnel-and-Gate trademark systems were considered. The emplacement methods selected for preliminary design and costing were slurry wall, driven/vibrated beam, deep soil mixing and hydrofracturing injection. For each of these methods, the iron must be slurried for ease of pumping and placement using biodegradable polymer viscosifiers that leave the iron reactive

  15. Groundwater sampling and chemical characterisation of the Laxemar deep borehole KLX02

    International Nuclear Information System (INIS)

    Laaksoharju, M.; Skaarman, C.; Smellie, J.; Nilsson, A.C.

    1995-02-01

    The Laxemar deep borehole, KLX02 (1705 m depth), located close to the Aespoe Hard Rock Laboratory (HRL), has been investigated. Groundwater sampling was conducted on two occasions and using different methods. The first sampling was taken in the open borehole using the so-called Tube sampler; the second sampling carried out using the SKB-packer equipment to isolate pre-determined borehole sections. Groundwater compositions consist of two distinct groupings; one shallow to intermediate Sodium-Bicarbonate type (Na(Ca,K):HC 3 Cl(SO 4 )) to a depth of 1000 m, and the other of deep origin, a calcium-chloride type (Ca-Na(K):Cl-SO 4 (Br)), occurring below 1000 m. The deep brines contain up to 46000 mg of Cl per litre. The influence of borehole activities are seen in the tritium data which record significant tritium down to 1000 m, and even to 1420 m. Mixing modelling shows that water from the 1960's is the main source for this tritium. The high tritium values in the 1090-1096.2 m section are due to contamination of 1% shallow water from 1960 and 2% of modern shallow water. The upper 800 m of bedrock at Laxemar lies within a groundwater recharge area; the sub-vertical to moderate angled fracture zones facilitate groundwater circulation to considerable depths, at least to 800 m, thus accounting for some of the low saline brackish groundwaters in these conducting fracture zones. Below 1000 m the system is hydraulically and geochemically 'closed' such that highly saline brines exist in a near-stagnant environment. 30 refs, 22 figs, 8 tabs

  16. Différenciations dans les parcours de formation post-obligatoire en Suisse. Constantes et changements Pathways’ differentiations in post-compulsory education in Switzerland. Stable and changing features

    Directory of Open Access Journals (Sweden)

    Elisabetta Pagnossin

    2011-10-01

    Full Text Available Les décisions concernant la formation post-obligatoire des jeunes suisses sont toujours très influencées par le genre. La répartition des filles et des garçons dans les filières de formation post-obligatoire n’a pas beaucoup évolué durant la dernière décennie bien que le niveau d’éducation des filles ait augmenté de manière importante. Le modèle traditionnel de division du travail et des rôles sociaux défini par le genre est encore très présent dans le pays. Il se reflète naturellement sur les choix éducatifs et professionnels, surtout des jeunes de 15 ans. Non seulement le choix de la filière, mais surtout celui du domaine d’étude, reste très genré. Des changements sont pourtant décelables, surtout dans l’orientation des filles, qui sont plus nombreuses à s’investir dans des formations atypiques. Cette tendance devrait se poursuivre.Decisions on post-compulsory education for the young Swiss are always highly gendered. The distribution of girls and boys in post-compulsory pathways has not much evolved for a decade even if the level of education reached by girls has increased a lot. The traditional model of the gendered division of labour and of social roles is still very present in the country. It is obviously reflected in educational choices especially for the 15 year-olds. Choices of pathways and more particularly choices of educational fields remain very gendered. Nonetheless, some changes can be detected particularly regarding the orientation of girls as they are keener on investing themselves in atypical training courses. This trend should continue.

  17. The deep ocean under climate change.

    Science.gov (United States)

    Levin, Lisa A; Le Bris, Nadine

    2015-11-13

    The deep ocean absorbs vast amounts of heat and carbon dioxide, providing a critical buffer to climate change but exposing vulnerable ecosystems to combined stresses of warming, ocean acidification, deoxygenation, and altered food inputs. Resulting changes may threaten biodiversity and compromise key ocean services that maintain a healthy planet and human livelihoods. There exist large gaps in understanding of the physical and ecological feedbacks that will occur. Explicit recognition of deep-ocean climate mitigation and inclusion in adaptation planning by the United Nations Framework Convention on Climate Change (UNFCCC) could help to expand deep-ocean research and observation and to protect the integrity and functions of deep-ocean ecosystems. Copyright © 2015, American Association for the Advancement of Science.

  18. SEDS: THE SPITZER EXTENDED DEEP SURVEY. SURVEY DESIGN, PHOTOMETRY, AND DEEP IRAC SOURCE COUNTS

    International Nuclear Information System (INIS)

    Ashby, M. L. N.; Willner, S. P.; Fazio, G. G.; Huang, J.-S.; Hernquist, L.; Hora, J. L.; Arendt, R.; Barmby, P.; Barro, G.; Faber, S.; Guhathakurta, P.; Bell, E. F.; Bouwens, R.; Cattaneo, A.; Croton, D.; Davé, R.; Dunlop, J. S.; Egami, E.; Finlator, K.; Grogin, N. A.

    2013-01-01

    The Spitzer Extended Deep Survey (SEDS) is a very deep infrared survey within five well-known extragalactic science fields: the UKIDSS Ultra-Deep Survey, the Extended Chandra Deep Field South, COSMOS, the Hubble Deep Field North, and the Extended Groth Strip. SEDS covers a total area of 1.46 deg 2 to a depth of 26 AB mag (3σ) in both of the warm Infrared Array Camera (IRAC) bands at 3.6 and 4.5 μm. Because of its uniform depth of coverage in so many widely-separated fields, SEDS is subject to roughly 25% smaller errors due to cosmic variance than a single-field survey of the same size. SEDS was designed to detect and characterize galaxies from intermediate to high redshifts (z = 2-7) with a built-in means of assessing the impact of cosmic variance on the individual fields. Because the full SEDS depth was accumulated in at least three separate visits to each field, typically with six-month intervals between visits, SEDS also furnishes an opportunity to assess the infrared variability of faint objects. This paper describes the SEDS survey design, processing, and publicly-available data products. Deep IRAC counts for the more than 300,000 galaxies detected by SEDS are consistent with models based on known galaxy populations. Discrete IRAC sources contribute 5.6 ± 1.0 and 4.4 ± 0.8 nW m –2 sr –1 at 3.6 and 4.5 μm to the diffuse cosmic infrared background (CIB). IRAC sources cannot contribute more than half of the total CIB flux estimated from DIRBE data. Barring an unexpected error in the DIRBE flux estimates, half the CIB flux must therefore come from a diffuse component.

  19. The deep lymphatic anatomy of the hand.

    Science.gov (United States)

    Ma, Chuan-Xiang; Pan, Wei-Ren; Liu, Zhi-An; Zeng, Fan-Qiang; Qiu, Zhi-Qiang

    2018-04-03

    The deep lymphatic anatomy of the hand still remains the least described in medical literature. Eight hands were harvested from four nonembalmed human cadavers amputated above the wrist. A small amount of 6% hydrogen peroxide was employed to detect the lymphatic vessels around the superficial and deep palmar vascular arches, in webs from the index to little fingers, the thenar and hypothenar areas. A 30-gauge needle was inserted into the vessels and injected with a barium sulphate compound. Each specimen was dissected, photographed and radiographed to demonstrate deep lymphatic distribution of the hand. Five groups of deep collecting lymph vessels were found in the hand: superficial palmar arch lymph vessel (SPALV); deep palmar arch lymph vessel (DPALV); thenar lymph vessel (TLV); hypothenar lymph vessel (HTLV); deep finger web lymph vessel (DFWLV). Each group of vessels drained in different directions first, then all turned and ran towards the wrist in different layers. The deep lymphatic drainage of the hand has been presented. The results will provide an anatomical basis for clinical management, educational reference and scientific research. Copyright © 2018 Elsevier GmbH. All rights reserved.

  20. Physical constraints in the deep hypolimnion of a subalpine lake driving planktonic Bacteria and Archaea distribution

    Directory of Open Access Journals (Sweden)

    Roberto Bertoni

    2010-06-01

    Full Text Available The study of the hydrodynamics of the hypolimnion of a deep holo-oligomictic lake (Lake Maggiore, Northern Italy, zmax¼370 m during the last 28 years showed that hypolimnetic waters remained isolated, not exchanging with the mixing zone even in winter when the full overturn conditions are most likely. The thickness of the isolated layer can range from 100 to 300 m. Thus, water masses of variable size reside in the lake for many years, and their physical and chemical conditions remain relatively unaffected by seasonal variability and epilimnetic imputs. In the hypolimnetic waters prokaryote abundance is three times lower than in the mixing layer but cell size is significantly higher. In addition, the relative abundance of Archaea and Crenarchaeota increases with depth in respect to that of Bacteria. The heterogeneous distribution of the two domains within the habitat can be attributed to the existence in the same environment of isolated water masses.

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