WorldWideScience

Sample records for comprehensive python-based system

  1. Python-Based Scientific Analysis and Visualization of Precipitation Systems at NASA Marshall Space Flight Center

    Science.gov (United States)

    Lang, Timothy J.

    2015-01-01

    At NASA Marshall Space Flight Center (MSFC), Python is used several different ways to analyze and visualize precipitating weather systems. A number of different Python-based software packages have been developed, which are available to the larger scientific community. The approach in all these packages is to utilize pre-existing Python modules as well as to be object-oriented and scalable. The first package that will be described and demonstrated is the Python Advanced Microwave Precipitation Radiometer (AMPR) Data Toolkit, or PyAMPR for short. PyAMPR reads geolocated brightness temperature data from any flight of the AMPR airborne instrument over its 25-year history into a common data structure suitable for user-defined analyses. It features rapid, simplified (i.e., one line of code) production of quick-look imagery, including Google Earth overlays, swath plots of individual channels, and strip charts showing multiple channels at once. These plotting routines are also capable of significant customization for detailed, publication-ready figures. Deconvolution of the polarization-varying channels to static horizontally and vertically polarized scenes is also available. Examples will be given of PyAMPR's contribution toward real-time AMPR data display during the Integrated Precipitation and Hydrology Experiment (IPHEx), which took place in the Carolinas during May-June 2014. The second software package is the Marshall Multi-Radar/Multi-Sensor (MRMS) Mosaic Python Toolkit, or MMM-Py for short. MMM-Py was designed to read, analyze, and display three-dimensional national mosaicked reflectivity data produced by the NOAA National Severe Storms Laboratory (NSSL). MMM-Py can read MRMS mosaics from either their unique binary format or their converted NetCDF format. It can also read and properly interpret the current mosaic design (4 regional tiles) as well as mosaics produced prior to late July 2013 (8 tiles). MMM-Py can easily stitch multiple tiles together to provide a

  2. Establishing a novel modeling tool: a python-based interface for a neuromorphic hardware system

    Directory of Open Access Journals (Sweden)

    Daniel Brüderle

    2009-06-01

    Full Text Available Neuromorphic hardware systems provide new possibilities for the neuroscience modeling community. Due to the intrinsic parallelism of the micro-electronic emulation of neural computation, such models are highly scalable without a loss of speed. However, the communities of software simulator users and neuromorphic engineering in neuroscience are rather disjoint. We present a software concept that provides the possibility to establish such hardware devices as valuable modeling tools. It is based on the integration of the hardware interface into a simulator-independent language which allows for unified experiment descriptions that can be run on various simulation platforms without modification, implying experiment portability and a huge simplification of the quantitative comparison of hardware and simulator results. We introduce an accelerated neuromorphic hardware device and describe the implementation of the proposed concept for this system. An example setup and results acquired by utilizing both the hardware system and a software simulator are demonstrated.

  3. Establishing a novel modeling tool: a python-based interface for a neuromorphic hardware system.

    Science.gov (United States)

    Brüderle, Daniel; Müller, Eric; Davison, Andrew; Muller, Eilif; Schemmel, Johannes; Meier, Karlheinz

    2009-01-01

    Neuromorphic hardware systems provide new possibilities for the neuroscience modeling community. Due to the intrinsic parallelism of the micro-electronic emulation of neural computation, such models are highly scalable without a loss of speed. However, the communities of software simulator users and neuromorphic engineering in neuroscience are rather disjoint. We present a software concept that provides the possibility to establish such hardware devices as valuable modeling tools. It is based on the integration of the hardware interface into a simulator-independent language which allows for unified experiment descriptions that can be run on various simulation platforms without modification, implying experiment portability and a huge simplification of the quantitative comparison of hardware and simulator results. We introduce an accelerated neuromorphic hardware device and describe the implementation of the proposed concept for this system. An example setup and results acquired by utilizing both the hardware system and a software simulator are demonstrated.

  4. A python based interface for the tandem-linac control system

    International Nuclear Information System (INIS)

    Ajith Kumar, B.P.

    2011-01-01

    The control system for the Tandem-LINAC accelerator system at IUAC is a client-server design running on a network of PCs under the GNU/Linux operating system. The computers connected to the devices in the accelerator run a server program. The computers providing the user interface runs different kinds of client programs that communicates to the servers over a TCT/IP network to control/monitor the accelerator parameters. Both the programs were written in C language and some programming expertise was required to write the client programs. The addition of a Python language interface has enabled the users to write programs for specific tasks like data logging and partial automation of the operation with minimal effort. (author)

  5. PyMUS: Python-Based Simulation Software for Virtual Experiments on Motor Unit System

    Directory of Open Access Journals (Sweden)

    Hojeong Kim

    2018-04-01

    Full Text Available We constructed a physiologically plausible computationally efficient model of a motor unit and developed simulation software that allows for integrative investigations of the input–output processing in the motor unit system. The model motor unit was first built by coupling the motoneuron model and muscle unit model to a simplified axon model. To build the motoneuron model, we used a recently reported two-compartment modeling approach that accurately captures the key cell-type-related electrical properties under both passive conditions (somatic input resistance, membrane time constant, and signal attenuation properties between the soma and the dendrites and active conditions (rheobase current and afterhyperpolarization duration at the soma and plateau behavior at the dendrites. To construct the muscle unit, we used a recently developed muscle modeling approach that reflects the experimentally identified dependencies of muscle activation dynamics on isometric, isokinetic and dynamic variation in muscle length over a full range of stimulation frequencies. Then, we designed the simulation software based on the object-oriented programing paradigm and developed the software using open-source Python language to be fully operational using graphical user interfaces. Using the developed software, separate simulations could be performed for a single motoneuron, muscle unit and motor unit under a wide range of experimental input protocols, and a hierarchical analysis could be performed from a single channel to the entire system behavior. Our model motor unit and simulation software may represent efficient tools not only for researchers studying the neural control of force production from a cellular perspective but also for instructors and students in motor physiology classroom settings.

  6. PyMUS: Python-Based Simulation Software for Virtual Experiments on Motor Unit System.

    Science.gov (United States)

    Kim, Hojeong; Kim, Minjung

    2018-01-01

    We constructed a physiologically plausible computationally efficient model of a motor unit and developed simulation software that allows for integrative investigations of the input-output processing in the motor unit system. The model motor unit was first built by coupling the motoneuron model and muscle unit model to a simplified axon model. To build the motoneuron model, we used a recently reported two-compartment modeling approach that accurately captures the key cell-type-related electrical properties under both passive conditions (somatic input resistance, membrane time constant, and signal attenuation properties between the soma and the dendrites) and active conditions (rheobase current and afterhyperpolarization duration at the soma and plateau behavior at the dendrites). To construct the muscle unit, we used a recently developed muscle modeling approach that reflects the experimentally identified dependencies of muscle activation dynamics on isometric, isokinetic and dynamic variation in muscle length over a full range of stimulation frequencies. Then, we designed the simulation software based on the object-oriented programing paradigm and developed the software using open-source Python language to be fully operational using graphical user interfaces. Using the developed software, separate simulations could be performed for a single motoneuron, muscle unit and motor unit under a wide range of experimental input protocols, and a hierarchical analysis could be performed from a single channel to the entire system behavior. Our model motor unit and simulation software may represent efficient tools not only for researchers studying the neural control of force production from a cellular perspective but also for instructors and students in motor physiology classroom settings.

  7. Python based high-level synthesis compiler

    Science.gov (United States)

    Cieszewski, Radosław; Pozniak, Krzysztof; Romaniuk, Ryszard

    2014-11-01

    This paper presents a python based High-Level synthesis (HLS) compiler. The compiler interprets an algorithmic description of a desired behavior written in Python and map it to VHDL. FPGA combines many benefits of both software and ASIC implementations. Like software, the mapped circuit is flexible, and can be reconfigured over the lifetime of the system. FPGAs therefore have the potential to achieve far greater performance than software as a result of bypassing the fetch-decode-execute operations of traditional processors, and possibly exploiting a greater level of parallelism. Creating parallel programs implemented in FPGAs is not trivial. This article describes design, implementation and first results of created Python based compiler.

  8. A Python-Based Open Source System for Geographic Object-Based Image Analysis (GEOBIA Utilizing Raster Attribute Tables

    Directory of Open Access Journals (Sweden)

    Daniel Clewley

    2014-06-01

    Full Text Available A modular system for performing Geographic Object-Based Image Analysis (GEOBIA, using entirely open source (General Public License compatible software, is presented based around representing objects as raster clumps and storing attributes as a raster attribute table (RAT. The system utilizes a number of libraries, developed by the authors: The Remote Sensing and GIS Library (RSGISLib, the Raster I/O Simplification (RIOS Python Library, the KEA image format and TuiView image viewer. All libraries are accessed through Python, providing a common interface on which to build processing chains. Three examples are presented, to demonstrate the capabilities of the system: (1 classification of mangrove extent and change in French Guiana; (2 a generic scheme for the classification of the UN-FAO land cover classification system (LCCS and their subsequent translation to habitat categories; and (3 a national-scale segmentation for Australia. The system presented provides similar functionality to existing GEOBIA packages, but is more flexible, due to its modular environment, capable of handling complex classification processes and applying them to larger datasets.

  9. Status of parallel Python-based implementation of UEDGE

    Science.gov (United States)

    Umansky, M. V.; Pankin, A. Y.; Rognlien, T. D.; Dimits, A. M.; Friedman, A.; Joseph, I.

    2017-10-01

    The tokamak edge transport code UEDGE has long used the code-development and run-time framework Basis. However, with the support for Basis expected to terminate in the coming years, and with the advent of the modern numerical language Python, it has become desirable to move UEDGE to Python, to ensure its long-term viability. Our new Python-based UEDGE implementation takes advantage of the portable build system developed for FACETS. The new implementation gives access to Python's graphical libraries and numerical packages for pre- and post-processing, and support of HDF5 simplifies exchanging data. The older serial version of UEDGE has used for time-stepping the Newton-Krylov solver NKSOL. The renovated implementation uses backward Euler discretization with nonlinear solvers from PETSc, which has the promise to significantly improve the UEDGE parallel performance. We will report on assessment of some of the extended UEDGE capabilities emerging in the new implementation, and will discuss the future directions. Work performed for U.S. DOE by LLNL under contract DE-AC52-07NA27344.

  10. A comprehensive radiology information system

    International Nuclear Information System (INIS)

    Jost, R.G.

    1985-01-01

    DECrad version II was recently tested by members of the Radiology Information System Consortium (RISC) and was found to meet the specifications prepared by the consortium. It is a comprehensive tailorable system that can be interfaced to practically any HIS. This paper provides an overall view of the major functions of the system which include registration, scheduling, tracking, film library management, reporting, statistics, and teaching modules. The evolution of the specification and user experiences is reported

  11. pyPaSWAS: Python-based multi-core CPU and GPU sequence alignment.

    Science.gov (United States)

    Warris, Sven; Timal, N Roshan N; Kempenaar, Marcel; Poortinga, Arne M; van de Geest, Henri; Varbanescu, Ana L; Nap, Jan-Peter

    2018-01-01

    Our previously published CUDA-only application PaSWAS for Smith-Waterman (SW) sequence alignment of any type of sequence on NVIDIA-based GPUs is platform-specific and therefore adopted less than could be. The OpenCL language is supported more widely and allows use on a variety of hardware platforms. Moreover, there is a need to promote the adoption of parallel computing in bioinformatics by making its use and extension more simple through more and better application of high-level languages commonly used in bioinformatics, such as Python. The novel application pyPaSWAS presents the parallel SW sequence alignment code fully packed in Python. It is a generic SW implementation running on several hardware platforms with multi-core systems and/or GPUs that provides accurate sequence alignments that also can be inspected for alignment details. Additionally, pyPaSWAS support the affine gap penalty. Python libraries are used for automated system configuration, I/O and logging. This way, the Python environment will stimulate further extension and use of pyPaSWAS. pyPaSWAS presents an easy Python-based environment for accurate and retrievable parallel SW sequence alignments on GPUs and multi-core systems. The strategy of integrating Python with high-performance parallel compute languages to create a developer- and user-friendly environment should be considered for other computationally intensive bioinformatics algorithms.

  12. NeoAnalysis: a Python-based toolbox for quick electrophysiological data processing and analysis.

    Science.gov (United States)

    Zhang, Bo; Dai, Ji; Zhang, Tao

    2017-11-13

    In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simultaneously with the experimental settings. However, most open-source toolboxes currently available for data analysis were developed to handle only a portion of the data and did not take into account the sorting of experimental conditions. Additionally, these toolboxes require that the input data be in a specific format, which can be inconvenient to users. Therefore, the development of a highly integrated toolbox that can process multiple types of data regardless of input data format and perform basic analysis for general electrophysiological experiments is incredibly useful. Here, we report the development of a Python based open-source toolbox, referred to as NeoAnalysis, to be used for quick electrophysiological data processing and analysis. The toolbox can import data from different data acquisition systems regardless of their formats and automatically combine different types of data into a single file with a standardized format. In cases where additional spike sorting is needed, NeoAnalysis provides a module to perform efficient offline sorting with a user-friendly interface. Then, NeoAnalysis can perform regular analog signal processing, spike train, and local field potentials analysis, behavioral response (e.g. saccade) detection and extraction, with several options available for data plotting and statistics. Particularly, it can automatically generate sorted results without requiring users to manually sort data beforehand. In addition, NeoAnalysis can organize all of the relevant data into an informative table on a trial-by-trial basis for data visualization. Finally, NeoAnalysis supports analysis at the population level. With the multitude of general-purpose functions provided

  13. π Scope: python based scientific workbench with visualization tool for MDSplus data

    Science.gov (United States)

    Shiraiwa, S.

    2014-10-01

    π Scope is a python based scientific data analysis and visualization tool constructed on wxPython and Matplotlib. Although it is designed to be a generic tool, the primary motivation for developing the new software is 1) to provide an updated tool to browse MDSplus data, with functionalities beyond dwscope and jScope, and 2) to provide a universal foundation to construct interface tools to perform computer simulation and modeling for Alcator C-Mod. It provides many features to visualize MDSplus data during tokamak experiments including overplotting different signals and discharges, various plot types (line, contour, image, etc.), in-panel data analysis using python scripts, and publication quality graphics generation. Additionally, the logic to produce multi-panel plots is designed to be backward compatible with dwscope, enabling smooth migration for dwscope users. πScope uses multi-threading to reduce data transfer latency, and its object-oriented design makes it easy to modify and expand while the open source nature allows portability. A built-in tree data browser allows a user to approach the data structure both from a GUI and a script, enabling relatively complex data analysis workflow to be built quickly. As an example, an IDL-based interface to perform GENRAY/CQL3D simulations was ported on πScope, thus allowing LHCD simulation to be run between-shot using C-Mod experimental profiles. This workflow is being used to generate a large database to develop a LHCD actuator model for the plasma control system. Supported by USDoE Award DE-FC02-99ER54512.

  14. Building and documenting workflows with python-based snakemake

    NARCIS (Netherlands)

    J. Köster (Johannes); S. Rahmann (Sven)

    2012-01-01

    textabstractSnakemake is a novel workflow engine with a simple Python-derived workflow definition language and an optimizing execution environment. It is the first system that supports multiple named wildcards (or variables) in input and output filenames of each rule definition. It also allows to

  15. Building and documenting workflows with python-based snakemake

    OpenAIRE

    Köster, Johannes; Rahmann, Sven

    2012-01-01

    textabstractSnakemake is a novel workflow engine with a simple Python-derived workflow definition language and an optimizing execution environment. It is the first system that supports multiple named wildcards (or variables) in input and output filenames of each rule definition. It also allows to write human-readable workflows that document themselves. We have found Snakemake especially useful for building high-throughput sequencing data analysis pipelines and present examples from this area....

  16. Historical Text Comprehension Reflective Tutorial Dialogue System

    Science.gov (United States)

    Grigoriadou, Maria; Tsaganou, Grammatiki; Cavoura, Theodora

    2005-01-01

    The Reflective Tutorial Dialogue System (ReTuDiS) is a system for learner modelling historical text comprehension through reflective dialogue. The system infers learners' cognitive profiles and constructs their learner models. Based on the learner model the system plans the appropriate--personalized for learners--reflective tutorial dialogue in…

  17. A Python-based Interface for Wide Coverage Lexicalized Tree-adjoining Grammars

    Directory of Open Access Journals (Sweden)

    Wang Ziqi

    2015-04-01

    Full Text Available This paper describes the design and implementation of a Python-based interface for wide coverage Lexicalized Tree-adjoining Grammars. The grammars are part of the XTAG Grammar project at the University of Pennsylvania, which were hand-written and semi-automatically curated to parse real-world corpora. We provide an interface to the wide coverage English and Korean XTAG grammars. Each XTAG grammar is lexicalized, which means at least one word selects a tree fragment (called an elementary tree or etree. Derivations for sentences are built by combining etrees using substitution (replacement of a tree node with an etree at the frontier of another etree and adjunction (replacement of an internal tree node in an etree by another etree. Each etree is associated with a feature structure representing constraints on substitution and adjunction. Feature structures are combined using unification during the combination of etrees. We plan to integrate our toolkit for XTAG grammars into the Python-based Natural Language Toolkit (NLTK: nltk.org. We have provided an API capable of searching the lexicalized etrees for a given word or multiple words, searching for a etree by name or function, display the lexicalized etrees to the user using a graphical view, display the feature structure associated with each tree node in an etree, hide or highlight features based on a regular expression, and browsing the entire tree database for each XTAG grammar.

  18. SBMLmod: a Python-based web application and web service for efficient data integration and model simulation.

    Science.gov (United States)

    Schäuble, Sascha; Stavrum, Anne-Kristin; Bockwoldt, Mathias; Puntervoll, Pål; Heiland, Ines

    2017-06-24

    Systems Biology Markup Language (SBML) is the standard model representation and description language in systems biology. Enriching and analysing systems biology models by integrating the multitude of available data, increases the predictive power of these models. This may be a daunting task, which commonly requires bioinformatic competence and scripting. We present SBMLmod, a Python-based web application and service, that automates integration of high throughput data into SBML models. Subsequent steady state analysis is readily accessible via the web service COPASIWS. We illustrate the utility of SBMLmod by integrating gene expression data from different healthy tissues as well as from a cancer dataset into a previously published model of mammalian tryptophan metabolism. SBMLmod is a user-friendly platform for model modification and simulation. The web application is available at http://sbmlmod.uit.no , whereas the WSDL definition file for the web service is accessible via http://sbmlmod.uit.no/SBMLmod.wsdl . Furthermore, the entire package can be downloaded from https://github.com/MolecularBioinformatics/sbml-mod-ws . We envision that SBMLmod will make automated model modification and simulation available to a broader research community.

  19. FluxPyt: a Python-based free and open-source software for 13C-metabolic flux analyses.

    Science.gov (United States)

    Desai, Trunil S; Srivastava, Shireesh

    2018-01-01

    13 C-Metabolic flux analysis (MFA) is a powerful approach to estimate intracellular reaction rates which could be used in strain analysis and design. Processing and analysis of labeling data for calculation of fluxes and associated statistics is an essential part of MFA. However, various software currently available for data analysis employ proprietary platforms and thus limit accessibility. We developed FluxPyt, a Python-based truly open-source software package for conducting stationary 13 C-MFA data analysis. The software is based on the efficient elementary metabolite unit framework. The standard deviations in the calculated fluxes are estimated using the Monte-Carlo analysis. FluxPyt also automatically creates flux maps based on a template for visualization of the MFA results. The flux distributions calculated by FluxPyt for two separate models: a small tricarboxylic acid cycle model and a larger Corynebacterium glutamicum model, were found to be in good agreement with those calculated by a previously published software. FluxPyt was tested in Microsoft™ Windows 7 and 10, as well as in Linux Mint 18.2. The availability of a free and open 13 C-MFA software that works in various operating systems will enable more researchers to perform 13 C-MFA and to further modify and develop the package.

  20. Comprehensive Lifecycle for Assuring System Safety

    Science.gov (United States)

    Knight, John C.; Rowanhill, Jonathan C.

    2017-01-01

    CLASS is a novel approach to the enhancement of system safety in which the system safety case becomes the focus of safety engineering throughout the system lifecycle. CLASS also expands the role of the safety case across all phases of the system's lifetime, from concept formation to decommissioning. As CLASS has been developed, the concept has been generalized to a more comprehensive notion of assurance becoming the driving goal, where safety is an important special case. This report summarizes major aspects of CLASS and contains a bibliography of papers that provide additional details.

  1. Evaluation of methods to reduce background using the Python-based ELISA_QC program.

    Science.gov (United States)

    Webster, Rose P; Cohen, Cinder F; Saeed, Fatima O; Wetzel, Hanna N; Ball, William J; Kirley, Terence L; Norman, Andrew B

    2018-05-01

    Almost all immunological approaches [immunohistochemistry, enzyme-linked immunosorbent assay (ELISA), Western blot], that are used to quantitate specific proteins have had to address high backgrounds due to non-specific reactivity. We report here for the first time a quantitative comparison of methods for reduction of the background of commercial biotinylated antibodies using the Python-based ELISA_QC program. This is demonstrated using a recombinant humanized anti-cocaine monoclonal antibody. Several approaches, such as adjustment of the incubation time and the concentration of blocking agent, as well as the dilution of secondary antibodies, have been explored to address this issue. In this report, systematic comparisons of two different methods, contrasted with other more traditional methods to address this problem are provided. Addition of heparin (HP) at 1 μg/ml to the wash buffer prior to addition of the secondary biotinylated antibody reduced the elevated background absorbance values (from a mean of 0.313 ± 0.015 to 0.137 ± 0.002). A novel immunodepletion (ID) method also reduced the background (from a mean of 0.331 ± 0.010 to 0.146 ± 0.013). Overall, the ID method generated more similar results at each concentration of the ELISA standard curve to that using the standard lot 1 than the HP method, as analyzed by the Python-based ELISA_QC program. We conclude that the ID method, while more laborious, provides the best solution to resolve the high background seen with specific lots of biotinylated secondary antibody. Copyright © 2018. Published by Elsevier B.V.

  2. Fuzzy comprehensive evaluation of district heating systems

    International Nuclear Information System (INIS)

    Wei Bing; Wang Songling; Li Li

    2010-01-01

    Selecting the optimal type of district heating (DH) system is of great importance because different heating systems have different levels of efficiency, which will impact the system economics, environment and energy use. In this study, seven DH systems were analysed and evaluated by the fuzzy comprehensive evaluation method. The dimensionless number-goodness was introduced into the calculation, the economics, environment and energy technology factors were considered synthetically, and the final goodness values were obtained. The results show that if only one of the economics, environment or energy technology factors are considered, different heating systems have different goodness values. When all three factors were taken into account, the final ranking of goodness values was: combined heating and power>gas-fired boiler>water-source heat pump>coal-fired boiler>ground-source heat pump>solar-energy heat pump>oil-fired boiler. The combined heating and power system is the best choice from all seven systems; the gas-fired boiler system is the best of the three boiler systems for heating purpose; and the water-source heat pump is the best of the three heat pump systems for heating and cooling.

  3. 34 CFR 303.321 - Comprehensive child find system.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Comprehensive child find system. 303.321 Section 303... Services Identification and Evaluation § 303.321 Comprehensive child find system. (a) General. (1) Each system must include a comprehensive child find system that is consistent with part B of the Act (see 34...

  4. PyCPR - a python-based implementation of the Conjugate Peak Refinement (CPR) algorithm for finding transition state structures.

    Science.gov (United States)

    Gisdon, Florian J; Culka, Martin; Ullmann, G Matthias

    2016-10-01

    Conjugate peak refinement (CPR) is a powerful and robust method to search transition states on a molecular potential energy surface. Nevertheless, the method was to the best of our knowledge so far only implemented in CHARMM. In this paper, we present PyCPR, a new Python-based implementation of the CPR algorithm within the pDynamo framework. We provide a detailed description of the theory underlying our implementation and discuss the different parts of the implementation. The method is applied to two different problems. First, we illustrate the method by analyzing the gauche to anti-periplanar transition of butane using a semiempirical QM method. Second, we reanalyze the mechanism of a glycyl-radical enzyme, namely of 4-hydroxyphenylacetate decarboxylase (HPD) using QM/MM calculations. In the end, we suggest a strategy how to use our implementation of the CPR algorithm. The integration of PyCPR into the framework pDynamo allows the combination of CPR with the large variety of methods implemented in pDynamo. PyCPR can be used in combination with quantum mechanical and molecular mechanical methods (and hybrid methods) implemented directly in pDynamo, but also in combination with external programs such as ORCA using pDynamo as interface. PyCPR is distributed as free, open source software and can be downloaded from http://www.bisb.uni-bayreuth.de/index.php?page=downloads . Graphical Abstract PyCPR is a search tool for finding saddle points on the potential energy landscape of a molecular system.

  5. Language comprehension warps the mirror neuron system

    Directory of Open Access Journals (Sweden)

    Noah eZarr

    2013-12-01

    Full Text Available Is the mirror neuron system (MNS used in language understanding? According to embodied accounts of language comprehension, understanding sentences describing actions makes use of neural mechanisms of action control, including the MNS. Consequently, repeatedly comprehending sentences describing similar actions should induce adaptation of the MNS thereby warping its use in other cognitive processes such as action recognition and prediction. To test this prediction, participants read blocks of multiple sentences where each sentence in the block described transfer of objects in a direction away or toward the reader. Following each block, adaptation was measured by having participants predict the end-point of videotaped actions. The adapting sentences disrupted prediction of actions in the same direction, but a only for videos of biological motion, and b only when the effector implied by the language (e.g., the hand matched the videos. These findings are signatures of the mirror neuron system.

  6. πScope: Python based scientific workbench with MDSplus data visualization tool

    Energy Technology Data Exchange (ETDEWEB)

    Shiraiwa, S., E-mail: shiraiwa@PSFC.MIT.EDU; Fredian, T.; Hillairet, J.; Stillerman, J.

    2016-11-15

    Highlights: • πScope provides great enhancement in MDSplus data visualization. • πScope provides a single platform for both data browsing and complicated analysis. • πScope is scriptable and easily expandable due to its object oriented. • πScope is written in python and available from (http://piscope.psfc.mit.edu/). - Abstract: A newly developed python based scientific data analysis and visualization tool, πScope ( (http://piscope.psfc.mit.edu)), is reported. The primary motivation is 1) to provide an updated tool to browse the MDSplus data beyond existing dwscope/jScope and 2) to realize a universal foundation to construct interface tools to perform computer modeling from experimental data. To visualize MDSplus data, πScope has many features including overplotting different signals and discharges, generating various plot types (line, contour, image, etc.), performing in-panel data analysis using python scripts, and producing publication quality graphics. The logic to generate multi-panel plots is designed to be backward compatible with dwscope, enabling smooth migration for users. πScope uses multi-threading in data loading, and is easy to modify and expand due to its object-oriented design. Furthermore, A user can access the data structure both from a GUI and a script, enabling relatively complex data analysis workflow built quickly on πScope.

  7. A new open-source Python-based Space Weather data access, visualization, and analysis toolkit

    Science.gov (United States)

    de Larquier, S.; Ribeiro, A.; Frissell, N. A.; Spaleta, J.; Kunduri, B.; Thomas, E. G.; Ruohoniemi, J.; Baker, J. B.

    2013-12-01

    Space weather research relies heavily on combining and comparing data from multiple observational platforms. Current frameworks exist to aggregate some of the data sources, most based on file downloads via web or ftp interfaces. Empirical models are mostly fortran based and lack interfaces with more useful scripting languages. In an effort to improve data and model access, the SuperDARN community has been developing a Python-based Space Science Data Visualization Toolkit (DaViTpy). At the center of this development was a redesign of how our data (from 30 years of SuperDARN radars) was made available. Several access solutions are now wrapped into one convenient Python interface which probes local directories, a new remote NoSQL database, and an FTP server to retrieve the requested data based on availability. Motivated by the efficiency of this interface and the inherent need for data from multiple instruments, we implemented similar modules for other space science datasets (POES, OMNI, Kp, AE...), and also included fundamental empirical models with Python interfaces to enhance data analysis (IRI, HWM, MSIS...). All these modules and more are gathered in a single convenient toolkit, which is collaboratively developed and distributed using Github and continues to grow. While still in its early stages, we expect this toolkit will facilitate multi-instrument space weather research and improve scientific productivity.

  8. πScope: Python based scientific workbench with MDSplus data visualization tool

    International Nuclear Information System (INIS)

    Shiraiwa, S.; Fredian, T.; Hillairet, J.; Stillerman, J.

    2016-01-01

    Highlights: • πScope provides great enhancement in MDSplus data visualization. • πScope provides a single platform for both data browsing and complicated analysis. • πScope is scriptable and easily expandable due to its object oriented. • πScope is written in python and available from (http://piscope.psfc.mit.edu/). - Abstract: A newly developed python based scientific data analysis and visualization tool, πScope ( (http://piscope.psfc.mit.edu)), is reported. The primary motivation is 1) to provide an updated tool to browse the MDSplus data beyond existing dwscope/jScope and 2) to realize a universal foundation to construct interface tools to perform computer modeling from experimental data. To visualize MDSplus data, πScope has many features including overplotting different signals and discharges, generating various plot types (line, contour, image, etc.), performing in-panel data analysis using python scripts, and producing publication quality graphics. The logic to generate multi-panel plots is designed to be backward compatible with dwscope, enabling smooth migration for users. πScope uses multi-threading in data loading, and is easy to modify and expand due to its object-oriented design. Furthermore, A user can access the data structure both from a GUI and a script, enabling relatively complex data analysis workflow built quickly on πScope.

  9. Language comprehension warps the mirror neuron system.

    Science.gov (United States)

    Zarr, Noah; Ferguson, Ryan; Glenberg, Arthur M

    2013-01-01

    Is the mirror neuron system (MNS) used in language understanding? According to embodied accounts of language comprehension, understanding sentences describing actions makes use of neural mechanisms of action control, including the MNS. Consequently, repeatedly comprehending sentences describing similar actions should induce adaptation of the MNS thereby warping its use in other cognitive processes such as action recognition and prediction. To test this prediction, participants read blocks of multiple sentences where each sentence in the block described transfer of objects in a direction away or toward the reader. Following each block, adaptation was measured by having participants predict the end-point of videotaped actions. The adapting sentences disrupted prediction of actions in the same direction, but (a) only for videos of biological motion, and (b) only when the effector implied by the language (e.g., the hand) matched the videos. These findings are signatures of the MNS.

  10. Comprehensive evaluation system of intelligent urban growth

    Science.gov (United States)

    Li, Lian-Yan; Ren, Xiao-Bin

    2017-06-01

    With the rapid urbanization of the world, urban planning has become increasingly important and necessary to ensure people have access to equitable and sustainable homes, resources and jobs.This article is to talk about building an intelligent city evaluation system.First,using System Analysis Model(SAM) which concludes literature data analysis and stepwise regression analysis to describe intelligent growth scientifically and obtain the evaluation index. Then,using the improved entropy method to obtain the weight of the evaluation index.Afterwards, establishing a complete Smart Growth Comprehensive Evaluation Model(SGCEM).Finally,testing the correctness of the model.Choosing Otago(New Zealand )and Yumen(China) as research object by data mining and SGCEM model,then we get Yumen and Otago’s rational degree’s values are 0.3485 and 0.5376 respectively. It’s believed that the Otago’s smart level is higher,and it is found that the estimated value of rationality is consistent with the reality.

  11. A comprehensive classification system for lipids

    NARCIS (Netherlands)

    Fahy, E.; Subramaniam, S.; Brown, H.A.; Glass, C.K.; Merrill, A.H.; Murphy, R.C.; Raetz, C.R.H.; Russell, D.W.; Seyama, Y.; Shaw, W.; Shimizu, T.; Spener, F.; van Meer, G.|info:eu-repo/dai/nl/068570368; VanNieuwenhze, M.S.; White, S.H.|info:eu-repo/dai/nl/304843539; Witztum, J.; Dennis, E.A.

    2005-01-01

    Lipids are produced, transported, and recognized by the concerted actions of numerous enzymes, binding proteins, and receptors. A comprehensive analysis of lipid molecules, “lipidomics,” in the context of genomics and proteomics is crucial to understanding cellular physiology and pathology;

  12. 34 CFR 303.165 - Comprehensive child find system.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Comprehensive child find system. 303.165 Section 303.165 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL... Requirements § 303.165 Comprehensive child find system. Each application must include— (a) The policies and...

  13. CLIMLAB: a Python-based software toolkit for interactive, process-oriented climate modeling

    Science.gov (United States)

    Rose, B. E. J.

    2015-12-01

    Global climate is a complex emergent property of the rich interactions between simpler components of the climate system. We build scientific understanding of this system by breaking it down into component process models (e.g. radiation, large-scale dynamics, boundary layer turbulence), understanding each components, and putting them back together. Hands-on experience and freedom to tinker with climate models (whether simple or complex) is invaluable for building physical understanding. CLIMLAB is an open-ended software engine for interactive, process-oriented climate modeling. With CLIMLAB you can interactively mix and match model components, or combine simpler process models together into a more comprehensive model. It was created primarily to support classroom activities, using hands-on modeling to teach fundamentals of climate science at both undergraduate and graduate levels. CLIMLAB is written in Python and ties in with the rich ecosystem of open-source scientific Python tools for numerics and graphics. The IPython notebook format provides an elegant medium for distributing interactive example code. I will give an overview of the current capabilities of CLIMLAB, the curriculum we have developed thus far, and plans for the future. Using CLIMLAB requires some basic Python coding skills. We consider this an educational asset, as we are targeting upper-level undergraduates and Python is an increasingly important language in STEM fields. However CLIMLAB is well suited to be deployed as a computational back-end for a graphical gaming environment based on earth-system modeling.

  14. SpacePy - a Python-based library of tools for the space sciences

    International Nuclear Information System (INIS)

    Morley, Steven K.; Welling, Daniel T.; Koller, Josef; Larsen, Brian A.; Henderson, Michael G.

    2010-01-01

    Space science deals with the bodies within the solar system and the interplanetary medium; the primary focus is on atmospheres and above - at Earth the short timescale variation in the the geomagnetic field, the Van Allen radiation belts and the deposition of energy into the upper atmosphere are key areas of investigation. SpacePy is a package for Python, targeted at the space sciences, that aims to make basic data analysis, modeling and visualization easier. It builds on the capabilities of the well-known NumPy and MatPlotLib packages. Publication quality output direct from analyses is emphasized. The SpacePy project seeks to promote accurate and open research standards by providing an open environment for code development. In the space physics community there has long been a significant reliance on proprietary languages that restrict free transfer of data and reproducibility of results. By providing a comprehensive, open-source library of widely used analysis and visualization tools in a free, modern and intuitive language, we hope that this reliance will be diminished. SpacePy includes implementations of widely used empirical models, statistical techniques used frequently in space science (e.g. superposed epoch analysis), and interfaces to advanced tools such as electron drift shell calculations for radiation belt studies. SpacePy also provides analysis and visualization tools for components of the Space Weather Modeling Framework - currently this only includes the BATS-R-US 3-D magnetohydrodynamic model and the RAM ring current model - including streamline tracing in vector fields. Further development is currently underway. External libraries, which include well-known magnetic field models, high-precision time conversions and coordinate transformations are wrapped for access from Python using SWIG and f2py. The rest of the tools have been implemented directly in Python. The provision of open-source tools to perform common tasks will provide openness in the

  15. A comprehensive review on intelligent surveillance systems

    Directory of Open Access Journals (Sweden)

    Sutrisno Warsono Ibrahim

    2016-05-01

    Full Text Available Intelligent surveillance system (ISS has received growing attention due to the increasing demand on security and safety. ISS is able to automatically analyze image, video, audio or other type of surveillance data without or with limited human intervention. The recent developments in sensor devices, computer vision, and machine learning have an important role in enabling such intelligent system. This paper aims to provide general overview of intelligent surveillance system and discuss some possible sensor modalities and their fusion scenarios such as visible camera (CCTV, infrared camera, thermal camera and radar. This paper also discusses main processing steps in ISS: background-foreground segmentation, object detection and classification, tracking, and behavioral analysis.

  16. Design Principles for a Comprehensive Library System.

    Science.gov (United States)

    Uluakar, Tamer; And Others

    1981-01-01

    Describes an online design featuring circulation control, catalog access, and serial holdings that uses an incremental approach to system development. Utilizing a dedicated computer, this second of three releases pays particular attention to present and predicted computing capabilities as well as trends in library automation. (Author/RAA)

  17. Comprehensive information system development and networking in ...

    African Journals Online (AJOL)

    Background/Aim: Hospital Information System(HIS) and Networking development is now the most important technology that must be embraced by all hospitals and clinics these days. Patients sometimes used to face problems in order to have quick and good services in the hospitals, often due to delay in searching for the ...

  18. Hotel software-comprehensive hotel systems

    OpenAIRE

    Šilhová, Lenka

    2010-01-01

    This bachelor's thesis deals with the usage of computer systems in the hotel industry. First part is focused on history, development and integration of technology into this field. Second part is dedicated to concrete products of the company Micros-Fidelio, which is the leader of hotel software market in the Czech Republic.

  19. The Mystro system: A comprehensive translator toolkit

    Science.gov (United States)

    Collins, W. R.; Noonan, R. E.

    1985-01-01

    Mystro is a system that facilities the construction of compilers, assemblers, code generators, query interpretors, and similar programs. It provides features to encourage the use of iterative enhancement. Mystro was developed in response to the needs of NASA Langley Research Center (LaRC) and enjoys a number of advantages over similar systems. There are other programs available that can be used in building translators. These typically build parser tables, usually supply the source of a parser and parts of a lexical analyzer, but provide little or no aid for code generation. In general, only the front end of the compiler is addressed. Mystro, on the other hand, emphasizes tools for both ends of a compiler.

  20. A comprehensive centralized control system for radiation waste treatment facility

    International Nuclear Information System (INIS)

    Kong Jinsong

    2014-01-01

    A comprehensive centralized control system is designed for the radiation waste treatment facility that lacking of coordinated operational mechanism for the radiation waste treatment. The centralized control and alarm linkage of various systems is implemented to ensure effectively the safety of nuclear facility and materials, improve the integral control ability through advanced informatization ways. (author)

  1. Security of Electronic Payment Systems: A Comprehensive Survey

    OpenAIRE

    Solat , Siamak

    2017-01-01

    This comprehensive survey deliberated over the security of electronic payment systems. In our research, we focused on either dominant systems or new attempts and innovations to improve the level of security of the electronic payment systems. This survey consists of the Card-present (CP) transactions and a review of its dominant system i.e. EMV including several researches at Cambridge university to designate variant types of attacks against this standard which demonstrates lack of a secure "o...

  2. Development of a comprehensive nuclear materials accountancy system at JAEA

    International Nuclear Information System (INIS)

    Takeda, Hideyuki; Usami, Masayuki; Hirosawa, Naonori; Fujita, Yoshihisa; Kodani, Yoshiki; Komata, Kazuhiro

    2007-01-01

    The Japan Atomic Energy Agency (JAEA) is submitting various types of accounting reports of international controlled materials to the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) based on domestic laws and regulations. JAEA developed a comprehensive Nuclear Material Accountancy System to achieve uniform management of the data of each facility by using a company-wide database. Personal computers in each facility are connected throughout the company using an in-house network to create the comprehensive Nuclear Material Accountancy System. This System uses personal computers to facilitate timely communication and for easy maintenance and operation. Efficient data processing and quality control functions for accountancy reporting are also realized by this System. In addition, the System has the ability to extract and summarize data about Plutonium Management in the company for public announcement. This report introduces and describes the details and functions of this System. (author)

  3. Update of the LIPID MAPS comprehensive classification system for lipids

    NARCIS (Netherlands)

    Fahy, E.; Subramaniam, S.; Murphy, R.C.; Nishijima, M.; Raetz, C.R.H.; Shimizu, T.; Spener, F.; van Meer, G.|info:eu-repo/dai/nl/068570368; Wakelam, M.J.O.; Dennis, E.A.

    2009-01-01

    In 2005, the International Lipid Classification and Nomenclature Committee under the sponsorship of the LIPID MAPS Consortium developed and established a “Comprehensive Classification System for Lipids” based on well-defined chemical and biochemical principles and using an ontology that is

  4. pyOpenMS: a Python-based interface to the OpenMS mass-spectrometry algorithm library.

    Science.gov (United States)

    Röst, Hannes L; Schmitt, Uwe; Aebersold, Ruedi; Malmström, Lars

    2014-01-01

    pyOpenMS is an open-source, Python-based interface to the C++ OpenMS library, providing facile access to a feature-rich, open-source algorithm library for MS-based proteomics analysis. It contains Python bindings that allow raw access to the data structures and algorithms implemented in OpenMS, specifically those for file access (mzXML, mzML, TraML, mzIdentML among others), basic signal processing (smoothing, filtering, de-isotoping, and peak-picking) and complex data analysis (including label-free, SILAC, iTRAQ, and SWATH analysis tools). pyOpenMS thus allows fast prototyping and efficient workflow development in a fully interactive manner (using the interactive Python interpreter) and is also ideally suited for researchers not proficient in C++. In addition, our code to wrap a complex C++ library is completely open-source, allowing other projects to create similar bindings with ease. The pyOpenMS framework is freely available at https://pypi.python.org/pypi/pyopenms while the autowrap tool to create Cython code automatically is available at https://pypi.python.org/pypi/autowrap (both released under the 3-clause BSD licence). © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Toward a Comprehensive System of Personnel Development in Deafblind Education.

    Science.gov (United States)

    Parker, Amy T; Nelson, Catherine

    2016-01-01

    Students who are deafblind are a unique population with unique needs for learning, communication, and environmental access. Two roles have been identified as important to their education: teacher of the deafblind and intervener. However, these roles are not officially recognized in most states. Because of this lack of recognition and the low incidence of deafblindness, it is difficult to sustain systems that prepare highly qualified personnel with advanced training and knowledge in educational strategies for children and youth who are deafblind. The authors propose a comprehensive system of personnel development (CSPD) for deafblind education. The components of this system are standards, preservice training, in-service/professional development, leadership development, research, and, finally, planning coordination, and evaluation. The authors describe elements of the model that are being implemented and provide suggestions to support the future development of a comprehensive system.

  6. Towards Python-based Domain-specific Languages for Self-reconfigurable Modular Robotics Research

    DEFF Research Database (Denmark)

    Moghadam, Mikael; Johan Christensen, David; Brandt, David

    2013-01-01

    This paper explores the role of operating system and high-level languages in the development of software and domain-specific languages (DSLs) for self-reconfigurable robotics. We review some of the current trends in self-reconfigurable robotics and describe the development of a software system...... for ATRON II which utilizes Linux and Python to significantly improve software abstraction and portability while providing some basic features which could prove useful when using Python, either stand-alone or via a DSL, on a self-reconfigurable robot system. These features include transparent socket...... communication, module identification, easy software transfer and reliable module-to-module communication. The end result is a software platform for modular robots that where appropriate builds on existing work in operating systems, virtual machines, middleware and high-level languages....

  7. Minimal canonical comprehensive Gröbner systems

    OpenAIRE

    Manubens, Montserrat; Montes, Antonio

    2009-01-01

    This is the continuation of Montes' paper "On the canonical discussion of polynomial systems with parameters''. In this paper, we define the Minimal Canonical Comprehensive Gröbner System of a parametric ideal and fix under which hypothesis it exists and is computable. An algorithm to obtain a canonical description of the segments of the Minimal Canonical CGS is given, thus completing the whole MCCGS algorithm (implemented in Maple and Singular). We show its high utility for applications, suc...

  8. Towards Python-based Domain-specific Languages for Self-reconfigurable Modular Robotics Research

    DEFF Research Database (Denmark)

    Moghadam, Mikael; Christensen, David Johan; Brandt, David

    2011-01-01

    communication, module identification, easy software transfer and reliable module-to-module communication. The end result is a software platform for modular robots that where appropriate builds on existing work in operating systems, virtual machines, middleware and high-level languages....

  9. [Comprehensive system integration and networking in operating rooms].

    Science.gov (United States)

    Feußner, H; Ostler, D; Kohn, N; Vogel, T; Wilhelm, D; Koller, S; Kranzfelder, M

    2016-12-01

    comprehensive surveillance and control system integrating all devices and functions is a precondition for realization of the operating room of the future. Multiple proprietary integrated operation room systems are currently available with a central user interface; however, they only cover a relatively small part of all functionalities. Internationally, there are at least three different initiatives to promote a comprehensive systems integration and networking in the operating room: the Japanese smart cyber operating theater (SCOT), the American medical device plug-and-play interoperability program (MDPnP) and the German secure and dynamic networking in operating room and hospital (OR.NET) project supported by the Federal Ministry of Education and Research. Within the framework of the internationally advanced OR.NET project, prototype solution approaches were realized, which make short-term and mid-term comprehensive data retrieval systems probable. An active and even autonomous control of the medical devices by the surveillance and control system (closed loop) is expected only in the long run due to strict regulatory barriers.

  10. GPAW - massively parallel electronic structure calculations with Python-based software

    DEFF Research Database (Denmark)

    Enkovaara, Jussi; Romero, Nichols A.; Shende, Sameer

    2011-01-01

    of the productivity enhancing features together with a good numerical performance. We have used this approach in implementing an electronic structure simulation software GPAW using the combination of Python and C programming languages. While the chosen approach works well in standard workstations and Unix...... popular choice. While dynamic, interpreted languages, such as Python, can increase the effciency of programmer, they cannot compete directly with the raw performance of compiled languages. However, by using an interpreted language together with a compiled language, it is possible to have most...... environments, massively parallel supercomputing systems can present some challenges in porting, debugging and profiling the software. In this paper we describe some details of the implementation and discuss the advantages and challenges of the combined Python/C approach. We show that despite the challenges...

  11. Python-based framework for coupled MC-TH reactor calculations

    International Nuclear Information System (INIS)

    Travleev, A.A.; Molitor, R.; Sanchez, V.

    2013-01-01

    We have developed a set of Python packages to provide a modern programming interface to codes used for analysis of nuclear reactors. Python classes can be classified by their functionality into three groups: low-level interfaces, general model classes and high-level interfaces. A low-level interface describes an interface between Python and a particular code. General model classes can be used to describe calculation geometry and meshes to represent system variables. High-level interface classes are used to convert geometry described with general model classes into instances of low-level interface classes and to put results of code calculations (read by low-interface classes) back to general model. The implementation of Python interfaces to the Monte Carlo neutronics code MCNP and thermo-hydraulic code SCF allow efficient description of calculation models and provide a framework for coupled calculations. In this paper we illustrate how these interfaces can be used to describe a pin model, and report results of coupled MCNP-SCF calculations performed for a PWR fuel assembly, organized by means of the interfaces

  12. A Comprehensive Method for Comparing Mental Models of Dynamic Systems

    OpenAIRE

    Schaffernicht, Martin; Grösser, Stefan N.

    2011-01-01

    Mental models are the basis on which managers make decisions even though external decision support systems may provide help. Research has demonstrated that more comprehensive and dynamic mental models seem to be at the foundation for improved policies and decisions. Eliciting and comparing such models can systematically explicate key variables and their main underlying structures. In addition, superior dynamic mental models can be identified. This paper reviews existing studies which measure ...

  13. An Introduction to Programming for Bioscientists: A Python-Based Primer.

    Directory of Open Access Journals (Sweden)

    Berk Ekmekci

    2016-06-01

    Full Text Available Computing has revolutionized the biological sciences over the past several decades, such that virtually all contemporary research in molecular biology, biochemistry, and other biosciences utilizes computer programs. The computational advances have come on many fronts, spurred by fundamental developments in hardware, software, and algorithms. These advances have influenced, and even engendered, a phenomenal array of bioscience fields, including molecular evolution and bioinformatics; genome-, proteome-, transcriptome- and metabolome-wide experimental studies; structural genomics; and atomistic simulations of cellular-scale molecular assemblies as large as ribosomes and intact viruses. In short, much of post-genomic biology is increasingly becoming a form of computational biology. The ability to design and write computer programs is among the most indispensable skills that a modern researcher can cultivate. Python has become a popular programming language in the biosciences, largely because (i its straightforward semantics and clean syntax make it a readily accessible first language; (ii it is expressive and well-suited to object-oriented programming, as well as other modern paradigms; and (iii the many available libraries and third-party toolkits extend the functionality of the core language into virtually every biological domain (sequence and structure analyses, phylogenomics, workflow management systems, etc.. This primer offers a basic introduction to coding, via Python, and it includes concrete examples and exercises to illustrate the language's usage and capabilities; the main text culminates with a final project in structural bioinformatics. A suite of Supplemental Chapters is also provided. Starting with basic concepts, such as that of a "variable," the Chapters methodically advance the reader to the point of writing a graphical user interface to compute the Hamming distance between two DNA sequences.

  14. An Introduction to Programming for Bioscientists: A Python-Based Primer.

    Science.gov (United States)

    Ekmekci, Berk; McAnany, Charles E; Mura, Cameron

    2016-06-01

    Computing has revolutionized the biological sciences over the past several decades, such that virtually all contemporary research in molecular biology, biochemistry, and other biosciences utilizes computer programs. The computational advances have come on many fronts, spurred by fundamental developments in hardware, software, and algorithms. These advances have influenced, and even engendered, a phenomenal array of bioscience fields, including molecular evolution and bioinformatics; genome-, proteome-, transcriptome- and metabolome-wide experimental studies; structural genomics; and atomistic simulations of cellular-scale molecular assemblies as large as ribosomes and intact viruses. In short, much of post-genomic biology is increasingly becoming a form of computational biology. The ability to design and write computer programs is among the most indispensable skills that a modern researcher can cultivate. Python has become a popular programming language in the biosciences, largely because (i) its straightforward semantics and clean syntax make it a readily accessible first language; (ii) it is expressive and well-suited to object-oriented programming, as well as other modern paradigms; and (iii) the many available libraries and third-party toolkits extend the functionality of the core language into virtually every biological domain (sequence and structure analyses, phylogenomics, workflow management systems, etc.). This primer offers a basic introduction to coding, via Python, and it includes concrete examples and exercises to illustrate the language's usage and capabilities; the main text culminates with a final project in structural bioinformatics. A suite of Supplemental Chapters is also provided. Starting with basic concepts, such as that of a "variable," the Chapters methodically advance the reader to the point of writing a graphical user interface to compute the Hamming distance between two DNA sequences.

  15. SRAC2006: A comprehensive neutronics calculation code system

    International Nuclear Information System (INIS)

    Okumura, Keisuke; Kugo, Teruhiko; Kaneko, Kunio; Tsuchihashi, Keichiro

    2007-02-01

    The SRAC is a code system applicable to neutronics analysis of a variety of reactor types. Since the publication of the second version of the users manual (JAERI-1302) in 1986 for the SRAC system, a number of additions and modifications to the functions and the library data have been made to establish a comprehensive neutronics code system. The current system includes major neutron data libraries (JENDL-3.3, JENDL-3.2, ENDF/B-VII, ENDF/B-VI.8, JEFF-3.1, JEF-2.2, etc.), and integrates five elementary codes for neutron transport and diffusion calculation; PIJ based on the collision probability method applicable to 16 kind of lattice models, S N transport codes ANISN(1D) and TWOTRN(2D), diffusion codes TUD(1D) and CITATION(multi-D). The system also includes an auxiliary code COREBN for multi-dimensional core burn-up calculation. (author)

  16. Research on airborne comprehensive survey system of atmosphere quality

    International Nuclear Information System (INIS)

    Yu Zhentao; Yu Yanbin

    1998-01-01

    The global atmosphere pollution is becoming more and more serious, affecting the human existence and development. Besides, the high spectrum resolution remote sensing technique, which has been applied to observe topographic features, identify military objectives and distinguish lithology and vegetation, has the relation to atmosphere quality and is influenced by atmosphere pollution (including radon pollution) and dust content in the atmosphere, it is imperative to monitor atmosphere quality. Based upon the selection of some main parameters evaluating atmospheric quality and necessary equipment, the author introduces the design of multiple airborne comprehensive survey system of atmosphere quality and how to deal with problems that crop up during the hardware designing and software programming

  17. PetClaw: Parallelization and Performance Optimization of a Python-Based Nonlinear Wave Propagation Solver Using PETSc

    KAUST Repository

    Alghamdi, Amal Mohammed

    2012-04-01

    Clawpack, a conservation laws package implemented in Fortran, and its Python-based version, PyClaw, are existing tools providing nonlinear wave propagation solvers that use state of the art finite volume methods. Simulations using those tools can have extensive computational requirements to provide accurate results. Therefore, a number of tools, such as BearClaw and MPIClaw, have been developed based on Clawpack to achieve significant speedup by exploiting parallel architectures. However, none of them has been shown to scale on a large number of cores. Furthermore, these tools, implemented in Fortran, achieve parallelization by inserting parallelization logic and MPI standard routines throughout the serial code in a non modular manner. Our contribution in this thesis research is three-fold. First, we demonstrate an advantageous use case of Python in implementing easy-to-use modular extensible scalable scientific software tools by developing an implementation of a parallelization framework, PetClaw, for PyClaw using the well-known Portable Extensible Toolkit for Scientific Computation, PETSc, through its Python wrapper petsc4py. Second, we demonstrate the possibility of getting acceptable Python code performance when compared to Fortran performance after introducing a number of serial optimizations to the Python code including integrating Clawpack Fortran kernels into PyClaw for low-level computationally intensive parts of the code. As a result of those optimizations, the Python overhead in PetClaw for a shallow water application is only 12 percent when compared to the corresponding Fortran Clawpack application. Third, we provide a demonstration of PetClaw scalability on up to the entirety of Shaheen; a 16-rack Blue Gene/P IBM supercomputer that comprises 65,536 cores and located at King Abdullah University of Science and Technology (KAUST). The PetClaw solver achieved above 0.98 weak scaling efficiency for an Euler application on the whole machine excluding the

  18. Control strategies for crane systems: A comprehensive review

    Science.gov (United States)

    Ramli, Liyana; Mohamed, Z.; Abdullahi, Auwalu M.; Jaafar, H. I.; Lazim, Izzuddin M.

    2017-10-01

    Crane systems are tremendously utilised in numerous heavy load transportation industries, and therefore, the control of crane systems is a well-established research field. As the last review paper was published more than a decade ago, there is a lack of collected and organised information regarding the latest and the newest updates on control strategies for crane control systems. Hence, this paper presents a comprehensive review of crane control strategies discussing the latest research works during the years from 2000 to 2016. Various crane types and control issues are highlighted, followed by the main focus of this paper, an extensive review of the control schemes for diverse types of crane systems that have been carried out in the 21st century. A brief review on modelling of single-pendulum and double-pendulum crane systems is also given. In addition, anti-sway control systems for industrial cranes that are available on the market is described. This paper summarises most of the related work and also pays a special focus on research trends regarding the control of crane systems that have been previously published in the literature. It is envisaged that this review paper will be helpful to new researchers when identifying research directions for this particular area of interest.

  19. Exposure management systems in emergencies as comprehensive medical care

    International Nuclear Information System (INIS)

    Shinohara, Teruhiko

    2000-01-01

    The emergency management of nuclear hazards relies on a comprehensive medical care system that includes accident prevention administration, environmental monitoring, a health physics organization, and a medical institution. In this paper, the care organization involved in the criticality accident at Tokai-mura is described, and the problems that need to be examined are pointed out. In that incident, even the expert was initially utterly confused and was unable to take appropriate measures. The author concluded that the members of the care organization were all untrained for dealing with nuclear hazards and radiation accidents. The education and training of personnel at the job site are important, and they are even more so for the leaders. Revisions of the regional disaster prevention plans and care manual are needed. (K.H.)

  20. The comprehensive intermodal planning system in distributed environment

    Directory of Open Access Journals (Sweden)

    Olgierd Dziamski

    2013-06-01

    Full Text Available Background: Goods distribution by containers has opened new opportunities for them in the global supply chain network. Standardization of transportation units allow to simplify transport logistics operations and enable the integration of different types of transport. Currently, container transport is the most popular means of transport by sea, but recent studies show an increase in its popularity in land transport. In the paper presented the concept of a comprehensive intermodal planning system in a distributed environment which enables more efficient use containers in the global transport. The aim of this paper was to formulate and develop new concept of Internet Intermodal Planning System in distribution environment, supporting the common interests of the consignors and the logistic service providers by integrating the transportation modes, routing, logistics operations and scheduling in order to create intermodal transport plans. Methods: In the paper presented and discussed the new approach to the management of logistics resources used in international intermodal transport. Detailed analysis of proposed classification of variety transportation means has been carried out along with their specific properties, which may affect the time and cost of transportation. Have been presented the modular web-based distribution planning system supporting container transportation planning. Conducted the analysis of the main planning process and curried out the discussion on the effectiveness of the new web-based container transport planning system. Result and conclusions: This paper presents a new concept of the distributed container transport planning system integrating the available on the market logistics service providers with freight exchange. Specific to container planning new transport categories has been identified which simplify and facilitate the management of intermodal planning process. The paper presents a modular structure of Integrated

  1. The value of residential photovoltaic systems: A comprehensive assessment

    Science.gov (United States)

    Borden, C. S.

    1983-01-01

    Utility-interactive photovoltaic (PV) arrays on residential rooftops appear to be a potentially attractive, large-scale application of PV technology. Results of a comprehensive assessment of the value (i.e., break-even cost) of utility-grid connected residential photovoltaic power systems under a variety of technological and economic assumptions are presented. A wide range of allowable PV system costs are calculated for small (4.34 kW (p) sub ac) residential PV systems in various locales across the United States. Primary factor in this variation are differences in local weather conditions, utility-specific electric generation capacity, fuel types, and customer-load profiles that effect purchase and sell-back rates, and non-uniform state tax considerations. Additional results from this analysis are: locations having the highest insolation values are not necessary the most economically attractive sites; residential PV systems connected in parallel to the utility demonstrate high percentages of energy sold back to the grid, and owner financial and tax assumptions cause large variations in break-even costs. Significant cost reduction and aggressive resolution of potential institutional impediments (e.g., liability, standards, metering, and technical integration) are required for a residential PV marker to become a major electric-grid-connected energy-generation source.

  2. A Diagnostic-Remediation Teaching System for Enhancing Elementary Students' Science Listening Comprehension

    Science.gov (United States)

    Lin, Sheau-Wen; Liu, Yu

    2017-01-01

    The purpose of this study was to explore elementary students' listening comprehension changes using a Web-based teaching system that can diagnose and remediate students' science listening comprehension problems during scientific inquiry. The 3-component system consisted of a 9-item science listening comprehension test, a 37-item diagnostic test,…

  3. Study on supporting system for operator's comprehensive understanding

    International Nuclear Information System (INIS)

    Yoshikawa, Shinji

    1996-01-01

    Power Reactor and Nuclear Fuel Development Corp. has participated in the development of a system to support the process of operator's plant understanding by the use of information processing techniques such as artificial intelligence since 1994. Analysis and model formation of the process leading to operator's comprehensive understanding of plant (mental model) are undertaken attempting to determine the basic structure of the mental model available for the description of knowledge using the precedent survey and to observe how to utilize operator's own knowledge. After consideration of the way by which plant operators utilize their physical knowledges and the knowledges of physical observation in practice, a basic structure composed of 3 components a qualitative causal network, a hierarchical function model and 3 links joining the two was proposed for the mental model. A questionnaire survey on operator's statements was made and the contents were assigned in several categories for objective analysis. An unified form usable to make a data base was established. Further, we have a plan to develop the first proto-type system to promote operator's understanding by 1998. (M.N.)

  4. Building a comprehensive geriatric health care system: a case study.

    Science.gov (United States)

    Bleiweiss, L; Simson, S

    1976-01-01

    This case study focuses on the efforts of three urban medical care institutions--a Health Maintenance Organization, a nursing home, and a university hospital--to form an interorganizational relationship. The purpose of the relationship was to utilize the services of the three organizations in order to respond to the comprehensive health needs of an urban geriatric population. Movements in this triadic organizational relationship are described and analyzed in terms of four conceptual stages--exploration, negotiation, interaction and performance, and termination. Problems arising during these stages were not resolved and the relationship was terminated after approximately two years of existence. A sociological discussion of the case focuses on why the relationship failed. The organizational relationship was disrupted by three stresses that occurred during the four stages of the relationship. Stresses emerged for each organization in the areas of organizational integration, professional coordination, and environmental adaptation, making it difficult for the three to become integrated into an organizational system. As a result, the HMO, the nursing home, and the hospital did not benefit from relationships that could have enabled them to develop the multi-organizational system necessary to sustain an innovative, comprehansive geriatric health project. If, as Whitehead said, the greatest invention of the nineteenth century was the invention of the method of invention, the task of the succedding century has been to organize inventiveness. The difference is not in the nature of invention or of inventors, but in the manner in which the context of social institutions is organized for their support.

  5. Advanced AEM by Comprehensive Analysis and Modeling of System Drift

    Science.gov (United States)

    Schiller, Arnulf; Klune, Klaus; Schattauer, Ingrid

    2010-05-01

    The quality of the assessment of risks outgoing from environmental hazards strongly depends on the spatial and temporal distribution of the data collected in a survey area. Natural hazards generally emerge from wide areas as it is in the case of volcanoes or land slides. Conventional surface measurements are restricted to few lines or locations and often can't be conducted in difficult terrain. So they only give a spatial and temporary limited data set and therefore limit the reliability of risk analysis. Aero-geophysical measurements potentially provide a valuable tool for completing the data set as they can be performed over a wide area, even above difficult terrain within a short time. A most desirable opportunity in course of such measurements is the ascertainment of the dynamics of such potentially hazardous environmental processes. This necessitates repeated and reproducible measurements. Current HEM systems can't accomplish this adequately due to their system immanent drift and - in some cases - bad signal to noise ratio. So, to develop comprising concepts for advancing state of the art HEM-systems to a valuable tool for data acquisition in risk assessment or hydrological problems, different studies have been undertaken which form the contents of the presented work conducted in course of the project HIRISK (Helicopter Based Electromagnetic System for Advanced Environmental Risk Assessment - FWF L-354 N10, supported by the Austrian Science Fund). The methodology is based upon two paths: A - Comprehensive experimental testing on an existing HEM system serving as an experimental platform. B - The setup of a numerical model which is continuously refined according to the results of the experimental data. The model then serves to simulate the experimental as well as alternative configurations and to analyze them subject to their drift behavior. Finally, concepts for minimizing the drift are derived and tested. Different test series - stationary on ground as well

  6. RODOS: a comprehensive European - integrated decision support system for Romania

    International Nuclear Information System (INIS)

    Mateescu, Gh.; Gheorghiu, Adriana; Gheorghiu, Dorina; Slavnicu, Dan; Craciunescu, Teddy

    1998-01-01

    This work is basically dedicated to RODOS (Real-time On-line DecisiOn support System), a comprehensive (computerized) decision support system ((C)DSS), integrated at European scale, which is in progress to be customized and implemented also for Romania to cope with the off-site response to nuclear emergencies. The first part deals with a short introduction regarding the need for a decision support system especially in case of a nuclear accident; there are also briefly reviewed the criteria one could demand that a CDSS should fulfill and the need for CDSS to give unequivocal answers to all encountered matters. Subsequently, there are mentioned some of the most known DSS in the world for off-site response to nuclear emergencies together with certain recent accomplishment of the IAEA in this field. The next chapter is dedicated to the four basic related projects (ECURIE, EURDEP, OSEP and RODOS) of the European Commission whose purpose consists in the optimisation of the nuclear emergency preparedness and response everywhere in Europe. Further on there are presented the basic features (the overall structure and functions), along with component software subsystems of the RODOS and, then, the background of RODOS implementation in Romania is reviewed (Romanian reasons to adhere to the RODOS project, needs, national legal framework and competent authorities in the nuclear domain, national radiological and meteorological networks. Finally, it is shortly reported the present status of RODOS customization and implementation in Romania (RODOS dedicated technical environment, collection of data and their transfer into RoGIS database, real-time on-line connection to networks, collection of data for countermeasure modules, source term assessment for CANDU-reactor, other related achievements) together with some concluding remarks. (authors)

  7. Plan for developing a comprehensive energy manpower information system

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, Lawrence G.

    1979-09-01

    The report is designed to make a beginning in broadening the scope of the comprehensive manpower information system for energy research, development, and demonstration, so that it could cover all manpower related to energy. It develops a plan for this extension, including determining which taxonomies require change, specifying the subsequent stages involved in expanding CEMIS to all energy manpower, and providing the basis for cost estimates for this work. The report is organized as follows: The analytical rationale is described in Chapter II. Chapter III reviews the status of manpower data in a number of energy sectors, notes limitations and gaps in the data, and discusses improvements and additions that should be made. The scope and structure of CEMIS are laid out in Chapter IV, with particular reference to the development of analytical processes, and of analytical linking functions between bodies of data, and a description of their application in anticipating the employment impact of energy changes. The appropriate steps recommended for the further development of CEMIS are described in Chapter V.

  8. Comprehensive Craniospinal Radiation for Controlling Central Nervous System Leukemia

    International Nuclear Information System (INIS)

    Walker, Gary V.; Shihadeh, Ferial; Kantarjian, Hagop; Allen, Pamela; Rondon, Gabriela; Kebriaei, Partow; O'Brien, Susan; Kedir, Aziza; Said, Mustefa; Grant, Jonathan D.; Thomas, Deborah A.; Gidley, Paul W.; Arzu, Isidora; Pinnix, Chelsea; Reed, Valerie; Dabaja, Bouthaina S.

    2014-01-01

    Purpose: To determine the benefit of radiation therapy (RT) in resolution of neurologic symptoms and deficits and whether the type of RT fields influences central nervous system (CNS) control in adults with CNS leukemia. Methods and Materials: A total of 163 adults from 1996 to 2012 were retrospectively analyzed. Potential associations between use of radiation and outcome were investigated by univariate and multivariate analysis. Results: The median survival time was 3.8 months after RT. Common presenting symptoms were headache in 79 patients (49%), cranial nerve VII deficit in 46 (28%), and cranial nerve II deficit in 44 (27%). RT was delivered to the base of skull in 48 patients (29%), to the whole brain (WB) in 67 (41%), and to the craniospinal axis (CS) in 48 (29%). Among 149 patients with a total of 233 deficits, resolution was observed in 34 deficits (15%), improvement in 126 deficits (54%), stability in 34 deficits (15%), and progression in 39 deficits (17%). The 12-month CNS progression-free survival was 77% among those receiving CS/WB and 51% among those receiving base of skull RT (P=.02). On multivariate analysis, patients who did not undergo stem cell transplantation after RT and base of skull RT were associated with worse CNS progression-free survival. Conclusions: Improvement or resolution of symptoms occurred in two thirds of deficits after RT. Comprehensive radiation to the WB or CS seems to offer a better outcome, especially in isolated CNS involvement

  9. Comprehensive Craniospinal Radiation for Controlling Central Nervous System Leukemia

    Energy Technology Data Exchange (ETDEWEB)

    Walker, Gary V.; Shihadeh, Ferial [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Kantarjian, Hagop [Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Allen, Pamela [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Rondon, Gabriela; Kebriaei, Partow [Department of Stem Cell Transplantation, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); O' Brien, Susan [Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Kedir, Aziza; Said, Mustefa; Grant, Jonathan D. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Thomas, Deborah A. [Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Gidley, Paul W. [Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Arzu, Isidora; Pinnix, Chelsea; Reed, Valerie [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Dabaja, Bouthaina S., E-mail: bdabaja@mdanderson.org [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2014-12-01

    Purpose: To determine the benefit of radiation therapy (RT) in resolution of neurologic symptoms and deficits and whether the type of RT fields influences central nervous system (CNS) control in adults with CNS leukemia. Methods and Materials: A total of 163 adults from 1996 to 2012 were retrospectively analyzed. Potential associations between use of radiation and outcome were investigated by univariate and multivariate analysis. Results: The median survival time was 3.8 months after RT. Common presenting symptoms were headache in 79 patients (49%), cranial nerve VII deficit in 46 (28%), and cranial nerve II deficit in 44 (27%). RT was delivered to the base of skull in 48 patients (29%), to the whole brain (WB) in 67 (41%), and to the craniospinal axis (CS) in 48 (29%). Among 149 patients with a total of 233 deficits, resolution was observed in 34 deficits (15%), improvement in 126 deficits (54%), stability in 34 deficits (15%), and progression in 39 deficits (17%). The 12-month CNS progression-free survival was 77% among those receiving CS/WB and 51% among those receiving base of skull RT (P=.02). On multivariate analysis, patients who did not undergo stem cell transplantation after RT and base of skull RT were associated with worse CNS progression-free survival. Conclusions: Improvement or resolution of symptoms occurred in two thirds of deficits after RT. Comprehensive radiation to the WB or CS seems to offer a better outcome, especially in isolated CNS involvement.

  10. NJOY: a comprehensive ENDF/B processing system

    International Nuclear Information System (INIS)

    MacFarlane, R.E.; Barrett, R.J.; Muir, D.W.; Boicourt, R.M.

    1978-01-01

    NJOY is the successor to the MINX code. It provides an efficient and accurate capability for processing ENDF/B-IV and -V data for use in fast reactor, thermal reactor, fusion reactor, shielding, and weapons analysis. NJOY produces neutron cross sections and group-to-group scattering matrices, heat production cross sections, photon production matrices, photon interaction cross sections and group-to-group matrices, delayed neutron spectra, thermal scattering cross sections and matrices, and cross-section covariances. Detailed pointwise cross sections, heating KERMA factors, thermal cross sections, and energy-to-energy thermal matrices are also available for plotting and Monte Carlo applications. NJOY currently processes all types of data on ENDF/B except for the decay chain and fission product yield files. NJOY provides output in the CCCC ISOTXS, BRKOXS, and DLAYXS formats, in DTF/ANISN format, and in a new comprehensive format called MATXS. Other important features of NJOY include free-format input, efficient binary I/O, dynamic storage allocation, an extremely modular structure, an accurate center-of-mass Gaussian integration for two-body scattering, and a flux calculator that makes it possible to compute accurate self-shielded cross sections when wide and intermediate-width resonance effects are important. NJOY is a single, integrated, efficient system that produces almost all of the basic cross sections required for multigroup methods of nuclear analysis. 3 figures, 4 tables

  11. [Self-esteem and giftedness: a Rorschach Comprehensive System study].

    Science.gov (United States)

    Kostogianni, N; Andronikof, A

    2014-02-01

    According to empirical literature, low self-esteem is highly correlated to behavioural and emotional problems in gifted children and adolescents. Since self-esteem is an indicator of social and emotional adjustment, it would be interesting to better understand the meaning of this construct, as it is evaluated explicitly with the use of self-report questionnaires. In order to explore the psychological processes underlying the explicit self-esteem, we studied the relation of a self-report questionnaire and an indirect measure of self and interpersonal perception using the Rorschach Comprehensive System (CS). The participants were 93 children, aged between 9 and 15 years old, with an IQ≥130. They were attending regular classes (no curriculum difference). Self-esteem was evaluated using the Coopersmith Self-Esteem Inventory (SEI). We used the Rorschach CS measures of self and interpersonal perception. The results showed no significant correlation between self-esteem and high IQ. A negative correlation between self-esteem evaluated on the SEI and the Rorschach Vista responses was found, which reflected self-critical introspection and painful self-appraisal. Then a positive correlation was observed between self-esteem and reflection answers on the Rorschach (Fr+rF>0), which are related to narcissistic-like features of personality. We also found a positive correlation between self-esteem and the Rorschach egocentricity index (EGO), which provides an estimate of self-concern. Finally, the strongest correlation was found between self-esteem and the dominance of good over poor human representations (GHR>PHR), which reveals effective interpersonal behaviour. The psychological processes which seem to be related to low self-esteem in gifted children and adolescents are maladaptive interpersonal behaviours, painful experience of introspection focusing on perceived negative aspects of the self, absence of narcissistic-like features of the personality and low self-concern. These

  12. Comprehensive evaluation on rationality of ventilation system in uranium underground mine

    International Nuclear Information System (INIS)

    Zhou Qinglin

    1991-01-01

    A new method is presented for evaluating rationality of uranium mine ventilation system using fuzzy mathematics. The mathematical models for fuzzy comprehensive evaluation are introduced. Based on practice of uranium mine ventilation, the evaluation factors and the evaluation procedure are given. Using the presented method, a comprehensive evaluation was carried out for ventilation systems before and after regulation in Fuzhou Uranium Mine

  13. Comprehensive Assessment Systems: Purposes and Implementation. Research Watch. E&R Report No. 11.10

    Science.gov (United States)

    Troy, Talbot

    2011-01-01

    A comprehensive assessment system is one in which three types of assessments: summative, benchmark, and formative assessments are routinely administered to all students in K-12 classrooms. The first part of this report summarizes the research on comprehensive assessment systems and provides clarity in terms of how each individual assessment type…

  14. Chapter 16 - Predictive Analytics for Comprehensive Energy Systems State Estimation

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yingchen [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Yang, Rui [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hodge, Brian S [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Zhang, Jie [University of Texas at Dallas; Weng, Yang [Arizona State University

    2017-12-01

    Energy sustainability is a subject of concern to many nations in the modern world. It is critical for electric power systems to diversify energy supply to include systems with different physical characteristics, such as wind energy, solar energy, electrochemical energy storage, thermal storage, bio-energy systems, geothermal, and ocean energy. Each system has its own range of control variables and targets. To be able to operate such a complex energy system, big-data analytics become critical to achieve the goal of predicting energy supplies and consumption patterns, assessing system operation conditions, and estimating system states - all providing situational awareness to power system operators. This chapter presents data analytics and machine learning-based approaches to enable predictive situational awareness of the power systems.

  15. Comprehensive analysis of a Radiology Operations Management computer system.

    Science.gov (United States)

    Arenson, R L; London, J W

    1979-11-01

    The Radiology Operations Management computer system at the Hospital of the University of Pennsylvania is discussed. The scheduling and file room modules are based on the system at Massachusetts General Hospital. Patient delays are indicated by the patient tracking module. A reporting module allows CRT/keyboard entry by transcriptionists, entry of standard reports by radiologists using bar code labels, and entry by radiologists using a specialty designed diagnostic reporting terminal. Time-flow analyses demonstrate a significant improvement in scheduling, patient waiting, retrieval of radiographs, and report delivery. Recovery of previously lost billing contributes to the proved cost effectiveness of this system.

  16. Framework for a comprehensive bridge management and information system.

    Science.gov (United States)

    2011-11-01

    "The purpose of this research project was to provide a framework for the development of a Bridge : Management Information System (BMIS). Researchers developed a synthesis of current BMIS development : activities and identified sources of data availab...

  17. Functional requirements for a comprehensive transportation location referencing system

    Science.gov (United States)

    2000-06-01

    Transportation agencies manage data that is referenced in one, two, three, and four dimensions. Location referencing system (LRS) data models vary across transportation agencies and often within organizations as well. This has resulted in failed atte...

  18. What is a comprehensive system of regulatory governance?

    International Nuclear Information System (INIS)

    Real diaz, F. J.

    2011-01-01

    The progressive evolution and diversification of regulations concerning industrial safety has made their management increasingly complex, requiring more resources of organizations. Therefore, it is advisable that this management be made more efficient through systematization, specialization and the use of computing technologies. This is supported by the implementation of integrated regulatory management systems. This article explain the concept of integrated regulatory management systems, their structure and their advantages. It also includes a model for implementing them in an organization. (Author)

  19. A Comprehensive Review on: Transdermal drug delivery systems.

    OpenAIRE

    Kharat, Rekha; Bathe, Ritesh Suresh

    2016-01-01

    Transdermal drug delivery system was introduced to overcome the difficulties of drug delivery through oral route. Despite their relatively higher costs, transdermal delivery systems have proved advantageous for delivery of selected drugs, such as estrogens, testosterone, clonidine and nitro-glycerine. Transdermal delivery provides a leading edge over injectable and oral routes by increasing patient compliance and avoiding first pass metabolism respectively. Topical  administration  of  therap...

  20. ImagePy: an open-source, Python-based and platform-independent software package for boimage analysis.

    Science.gov (United States)

    Wang, Anliang; Yan, Xiaolong; Wei, Zhijun

    2018-04-27

    This note presents the design of a scalable software package named ImagePy for analysing biological images. Our contribution is concentrated on facilitating extensibility and interoperability of the software through decoupling the data model from the user interface. Especially with assistance from the Python ecosystem, this software framework makes modern computer algorithms easier to be applied in bioimage analysis. ImagePy is free and open source software, with documentation and code available at https://github.com/Image-Py/imagepy under the BSD license. It has been tested on the Windows, Mac and Linux operating systems. wzjdlut@dlut.edu.cn or yxdragon@imagepy.org.

  1. A Comprehensive System for Monitoring Urban Accessibility in Smart Cities.

    Science.gov (United States)

    Mora, Higinio; Gilart-Iglesias, Virgilio; Pérez-Del Hoyo, Raquel; Andújar-Montoya, María Dolores

    2017-08-09

    The present work discusses the possibilities offered by the evolution of Information and Communication Technologies with the aim of designing a system to dynamically obtain knowledge of accessibility issues in urban environments. This system is facilitated by technology to analyse the urban user experience and movement accessibility, which enabling accurate identification of urban barriers and monitoring its effectiveness over time. Therefore, the main purpose of the system is to meet the real needs and requirements of people with movement disabilities. The information obtained can be provided as a support service for decision-making to be used by city government, institutions, researchers, professionals and other individuals of society in general to improve the liveability and quality of the lives of citizens. The proposed system is a means of social awareness that makes the most vulnerable groups of citizens visible by involving them as active participants. To perform and implement the system, the latest communication and positioning technologies for smart sensing have been used, as well as the cloud computing paradigm. Finally, to validate the proposal, a case study has been presented using the university environment as a pre-deployment step in urban environments.

  2. ParFit: A Python-Based Object-Oriented Program for Fitting Molecular Mechanics Parameters to ab Initio Data.

    Science.gov (United States)

    Zahariev, Federico; De Silva, Nuwan; Gordon, Mark S; Windus, Theresa L; Dick-Perez, Marilu

    2017-03-27

    A newly created object-oriented program for automating the process of fitting molecular-mechanics parameters to ab initio data, termed ParFit, is presented. ParFit uses a hybrid of deterministic and stochastic genetic algorithms. ParFit can simultaneously handle several molecular-mechanics parameters in multiple molecules and can also apply symmetric and antisymmetric constraints on the optimized parameters. The simultaneous handling of several molecules enhances the transferability of the fitted parameters. ParFit is written in Python, uses a rich set of standard and nonstandard Python libraries, and can be run in parallel on multicore computer systems. As an example, a series of phosphine oxides, important for metal extraction chemistry, are parametrized using ParFit. ParFit is in an open source program available for free on GitHub ( https://github.com/fzahari/ParFit ).

  3. Unobtrusive and comprehensive health screening using an intelligent toilet system.

    Science.gov (United States)

    Schlebusch, Thomas; Fichtner, Wolfgang; Mertig, Michael; Leonhardt, Steffen

    2015-02-01

    Home monitoring is a promising technology to deal with the increasing amount of chronically ill patients while ensuring quality of medical care. Most systems available today depend on a high degree of interaction between the user and the device. Especially for people relying on advanced levels of care, this scheme is impracticable. In this paper, we are presenting an "intelligent toilet" performing an extensive health check while being as simple to use as a conventional toilet. The main focus of the system is to support the treatment of diabetes and chronic heart failure, but additional applications are possible.

  4. Elements of a system for verifying a Comprehensive Test Ban

    International Nuclear Information System (INIS)

    Hannon, W.J.

    1987-01-01

    The paper discusses the goals of a monitoring system for a CTB, its functions, the challenges to verification, discrimination techniques, and some recent developments. It is concluded technical, military and political efforts are required to establish and verify test ban treaties which will contribute to stability in the long term. It currently appears there will be a significant number of unidentified events

  5. TURBOVEG, a comprehensive data base management system for vegetation data

    NARCIS (Netherlands)

    Hennekens, S.M.; Schaminée, J.H.J.

    2001-01-01

    The computer software package TURBOVEG was developed in The Netherlands for the processing of phytosociological data. This package comprises an easy-to-use database management system. The data bank to be managed can be divided into several databases which may consist of up to 100 000 relevés each.

  6. The Unlock Project: a Python-based framework for practical brain-computer interface communication "app" development.

    Science.gov (United States)

    Brumberg, Jonathan S; Lorenz, Sean D; Galbraith, Byron V; Guenther, Frank H

    2012-01-01

    In this paper we present a framework for reducing the development time needed for creating applications for use in non-invasive brain-computer interfaces (BCI). Our framework is primarily focused on facilitating rapid software "app" development akin to current efforts in consumer portable computing (e.g. smart phones and tablets). This is accomplished by handling intermodule communication without direct user or developer implementation, instead relying on a core subsystem for communication of standard, internal data formats. We also provide a library of hardware interfaces for common mobile EEG platforms for immediate use in BCI applications. A use-case example is described in which a user with amyotrophic lateral sclerosis participated in an electroencephalography-based BCI protocol developed using the proposed framework. We show that our software environment is capable of running in real-time with updates occurring 50-60 times per second with limited computational overhead (5 ms system lag) while providing accurate data acquisition and signal analysis.

  7. Review of Comprehensive Evaluation Methods for Power Quality and Its Trend in New Generation Energy System

    Science.gov (United States)

    Liu, Ruihua; Wang, Rong; Liu, Qunying; Yang, Li; Xi, Chuan; Wang, Wei; Li, Lingzhou; Zhao, Zhoufang; Zhou, Ying

    2018-02-01

    With China’s new energy generation grid connected capacity being in the forefront of the world and the uncertainty of new energy sources, such as wind energy and solar energy, it is be of great significance to study scientific and comprehensive assessment of power quality. On the foundation of analysizing the current power quality index systematically and objectively, the new energy grid power quality analysis method and comprehensive evaluation method, this paper tentatively explored the trend of the new generation of energy system power quality comprehensive evaluation.

  8. Development of a comprehensive radioactive waste classification system

    International Nuclear Information System (INIS)

    Smith, C.F.; Cohen, J.J.

    1989-01-01

    Several previous studies have been conducted with the intent of developing a rational system for classification of radioactive wastes. Although none of the proposed systems has gained general acceptance, certain waste classes, specifically high-level waste and low-level waste suitable for shallow land burial have been essentially defined by regulation. Wastes which remain undefined include: those intermediate level wastes which require more restrictive controls than that provided by shallow land burial but not the high degree of isolation needed for high level wastes, and wastes below regulatory concern (BRC) which entail so low a radiological risk that they can be managed according to their nonradiological properties. This study has developed a framework within which the complete spectrum of radioactive wastes can be defined

  9. Comprehensive Final Report for the Marine Seismic System Program

    Science.gov (United States)

    1985-08-01

    serve as a principal reference for transitioning marine seismic system techniques and results from the research and development arena to the...vM . .’ .■ .» .%■■.•. - Viaj ^."-;/-.■■ *• -’•’■■’■ ■ ■ - ■ • ■ -. . -. • ^;-■:■:-:•:> •■•."--.--.v. ’-• V ’.■ *.- ".i • ■ - ■ ■ v V

  10. Practical Modeling and Comprehensive System Identification of a BLDC Motor

    Directory of Open Access Journals (Sweden)

    Changle Xiang

    2015-01-01

    Full Text Available The aim of this paper is to outline all the steps in a rigorous and simple procedure for system identification of BLDC motor. A practical mathematical model for identification is derived. Frequency domain identification techniques and time domain estimation method are combined to obtain the unknown parameters. The methods in time domain are founded on the least squares approximation method and a disturbance observer. Only the availability of experimental data for rotor speed and armature current are required for identification. The proposed identification method is systematically investigated, and the final identified model is validated by experimental results performed on a typical BLDC motor in UAV.

  11. Socio-technological study for establishing comprehensive nuclear safety system

    International Nuclear Information System (INIS)

    Furuta, Kazuo; Kanno, Taro; Yagi, Ekou; Shuto, Yuki

    2003-01-01

    This paper presents an overview and preliminary results of a research project on social-technology for nuclear safety, which started in October 2001. In particular, emergency response preparedness against nuclear disaster and consensus development will be discussed. The architecture of an emergency response simulator will be given, which is for assessing design of disaster prevention systems. A conceptual model of evacuation behavior of a resident has been constructed from analysis of past disaster cases. As for consensus development, deliberation spaces of actual committee meetings were constructed by analyzing transcripts of the meetings based on an opinion schema. A model of consensus development process has been proposed from the traces of participants' opinions over the deliberation spaces. Such a socio-technological approach will be useful not only for nuclear safety but also for safety of non-nuclear domains and human activities of a high hazard potential; it is expected to contribute to establishing risk-aware society of the future. (author)

  12. Comprehensive approach to systemic sclerosis patients during pregnancy.

    Science.gov (United States)

    Rueda de León Aguirre, Alexandra; Ramírez Calvo, José Antonio; Rodríguez Reyna, Tatiana Sofía

    2015-01-01

    Systemic sclerosis (SSc) is a connective tissue disease that usually affects women, with a male:female ratio of 1:4-10. It was thought that there was a prohibitive risk of fatal complications in the pregnancies of patients with SSc. It is now known that the majority of these women undergo a normal progression of pregnancy if the right time is chosen and a close obstetric care is delivered. The obstetric risk will depend on the subtype and clinical stage of the disease, and the presence and severity of the internal organ involvement during the pregnancy. The management of these pregnancies should be provided in a specialized center, with a multidisciplinary team capable of identifying and promptly treating complications. Treatment should be limited to drugs with no teratogenic potential, except when renal crises or severe cardiovascular complications develop. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

  13. A COMPREHENSIVE TECHNICAL REVIEW OF THE DEMONSTRATION BULK VITRIFICATION SYSTEM

    International Nuclear Information System (INIS)

    SCHAUS, P.S.

    2006-01-01

    In May 2006, CH2M Hill Hanford Group, Inc. chartered an Expert Review Panel (ERP) to review the current status of the Demonstration Bulk Vitrification System (DBVS). It is the consensus of the ERP that bulk vitrification is a technology that requires further development and evaluation to determine its potential for meeting the Hanford waste stabilization mission. No fatal flaws (issues that would jeopardize the overall DBVS mission that cannot be mitigated) were found, given the current state of the project. However, a number of technical issues were found that could significantly affect the project's ability to meet its overall mission as stated in the project ''Justification of Mission Need'' document, if not satisfactorily resolved. The ERP recognizes that the project has changed from an accelerated schedule demonstration project to a formally chartered project that must be in full compliance with DOE 413.3 requirements. The perspective of the ERP presented herein, is measured against the formally chartered project as stated in the approved Justification of Mission Need document. A justification of Mission Need document was approved in July 2006 which defined the objectives for the DBVS Project. In this document, DOE concluded that bulk vitrification is a viable technology that requires additional development to determine its potential applicability to treatment of a portion of the Hanford low activity waste. The DBVS mission need statement now includes the following primary objectives: (1) process approximately 190,000 gallons of Tank S-109 waste into fifty 100 metric ton boxes of vitrified product; (2) store and dispose of these boxes at Hanford's Integrated Disposal Facility (IDF); (3) evaluate the waste form characteristics; (4) gather pilot plant operability data, and (5) develop the overall life cycle system performance of bulk vitrification and produce a comparison of the bulk vitrification process to building a second LAW Immobilization facility or other

  14. Comprehensive characterizations of nanoparticle biodistribution following systemic injection in mice

    Science.gov (United States)

    Liao, Wei-Yin; Li, Hui-Jing; Chang, Ming-Yao; Tang, Alan C. L.; Hoffman, Allan S.; Hsieh, Patrick C. H.

    2013-10-01

    Various nanoparticle (NP) properties such as shape and surface charge have been studied in an attempt to enhance the efficacy of NPs in biomedical applications. When trying to undermine the precise biodistribution of NPs within the target organs, the analytical method becomes the determining factor in measuring the precise quantity of distributed NPs. High performance liquid chromatography (HPLC) represents a more powerful tool in quantifying NP biodistribution compared to conventional analytical methods such as an in vivo imaging system (IVIS). This, in part, is due to better curve linearity offered by HPLC than IVIS. Furthermore, HPLC enables us to fully analyze each gram of NPs present in the organs without compromising the signals and the depth-related sensitivity as is the case in IVIS measurements. In addition, we found that changing physiological conditions improved large NP (200-500 nm) distribution in brain tissue. These results reveal the importance of selecting analytic tools and physiological environment when characterizing NP biodistribution for future nanoscale toxicology, therapeutics and diagnostics.Various nanoparticle (NP) properties such as shape and surface charge have been studied in an attempt to enhance the efficacy of NPs in biomedical applications. When trying to undermine the precise biodistribution of NPs within the target organs, the analytical method becomes the determining factor in measuring the precise quantity of distributed NPs. High performance liquid chromatography (HPLC) represents a more powerful tool in quantifying NP biodistribution compared to conventional analytical methods such as an in vivo imaging system (IVIS). This, in part, is due to better curve linearity offered by HPLC than IVIS. Furthermore, HPLC enables us to fully analyze each gram of NPs present in the organs without compromising the signals and the depth-related sensitivity as is the case in IVIS measurements. In addition, we found that changing physiological

  15. Acquire: an open-source comprehensive cancer biobanking system.

    Science.gov (United States)

    Dowst, Heidi; Pew, Benjamin; Watkins, Chris; McOwiti, Apollo; Barney, Jonathan; Qu, Shijing; Becnel, Lauren B

    2015-05-15

    The probability of effective treatment of cancer with a targeted therapeutic can be improved for patients with defined genotypes containing actionable mutations. To this end, many human cancer biobanks are integrating more tightly with genomic sequencing facilities and with those creating and maintaining patient-derived xenografts (PDX) and cell lines to provide renewable resources for translational research. To support the complex data management needs and workflows of several such biobanks, we developed Acquire. It is a robust, secure, web-based, database-backed open-source system that supports all major needs of a modern cancer biobank. Its modules allow for i) up-to-the-minute 'scoreboard' and graphical reporting of collections; ii) end user roles and permissions; iii) specimen inventory through caTissue Suite; iv) shipping forms for distribution of specimens to pathology, genomic analysis and PDX/cell line creation facilities; v) robust ad hoc querying; vi) molecular and cellular quality control metrics to track specimens' progress and quality; vii) public researcher request; viii) resource allocation committee distribution request review and oversight and ix) linkage to available derivatives of specimen. © The Author 2015. Published by Oxford University Press.

  16. The Essence and Phases of the Comprehensive System of Ensuring the Economic Security of Enterprise

    Science.gov (United States)

    Ianioglo, Alina; Polajeva, Tatjana

    2017-01-01

    In present conditions of instability of the environment, entrepreneurs assume the most of the business risks. In this regard, problems of ensuring the economic security become particularly important. The comprehensive system of ensuring the economic security of enterprise was worked out and the results are presented in the article. This system is…

  17. A System for Planning and Achieving Comprehensive Health Care in Residential Institutions for the Mentally Retarded.

    Science.gov (United States)

    Decker, Harold A.

    Based on a view of health care intertwining medicine intimately with other components of institutional care, the monograph presents a system of concepts and operating techniques for providing comprehensive health care to institutionalized retardates. Background of the system is explained in terms of its research basis (two studies by the author of…

  18. A Web GIS Enabled Comprehensive Hydrologic Information System for Indian Water Resources Systems

    Science.gov (United States)

    Goyal, A.; Tyagi, H.; Gosain, A. K.; Khosa, R.

    2017-12-01

    Hydrological systems across the globe are getting increasingly water stressed with each passing season due to climate variability & snowballing water demand. Hence, to safeguard food, livelihood & economic security, it becomes imperative to employ scientific studies for holistic management of indispensable resource like water. However, hydrological study of any scale & purpose is heavily reliant on various spatio-temporal datasets which are not only difficult to discover/access but are also tough to use & manage. Besides, owing to diversity of water sector agencies & dearth of standard operating procedures, seamless information exchange is challenging for collaborators. Extensive research is being done worldwide to address these issues but regrettably not much has been done in developing countries like India. Therefore, the current study endeavours to develop a Hydrological Information System framework in a Web-GIS environment for empowering Indian water resources systems. The study attempts to harmonize the standards for metadata, terminology, symbology, versioning & archiving for effective generation, processing, dissemination & mining of data required for hydrological studies. Furthermore, modelers with humble computing resources at their disposal, can consume this standardized data in high performance simulation modelling using cloud computing within the developed Web-GIS framework. They can also integrate the inputs-outputs of different numerical models available on the platform and integrate their results for comprehensive analysis of the chosen hydrological system. Thus, the developed portal is an all-in-one framework that can facilitate decision makers, industry professionals & researchers in efficient water management.

  19. Comprehensive analysis of the mechanical system system “fixture – workpiece”

    Directory of Open Access Journals (Sweden)

    V. Ivanov

    2017-05-01

    Full Text Available Present work is devoted to locating and clamping of prismatic parts in fixtures during the machining on drilling-milling-boring machines. The special feature of locating schemes of parts of the present type is that one of the flat surfaces is used as a datum (3 contact points ensuring stability, convenience of locating and vibration elimination during the machining process. Within the scope of the presented work, the comprehensive mathematical model of the system “fixture – workpiece” has been developed taking into account technological features of locating and clamping processes of workpiece in fixture. The methodology of determination of the rigidity of the cutting tool and functional elements has been proposed. As a result, the static and dynamic analysis of the workpiece in the fixture under the effect of spatial system of cutting and clamping forces is being determined. In addition, the free frequencies of the system “fixture-workpiece” and forms of the free and forced vibrations, frequency-response characteristics are being determined. Keywords: locating chart, functional element, rigidity, free vibrations, free frequency, forced vibrations, cutting force, frequency-response characteristic

  20. A Comprehensive Evaluation System for Military Hospitals' Response Capability to Bio-terrorism.

    Science.gov (United States)

    Wang, Hui; Jiang, Nan; Shao, Sicong; Zheng, Tao; Sun, Jianzhong

    2015-05-01

    The objective of this study is to establish a comprehensive evaluation system for military hospitals' response capacity to bio-terrorism. Literature research and Delphi method were utilized to establish the comprehensive evaluation system for military hospitals' response capacity to bio-terrorism. Questionnaires were designed and used to survey the status quo of 134 military hospitals' response capability to bio-terrorism. Survey indicated that factor analysis method was suitable to for analyzing the comprehensive evaluation system for military hospitals' response capacity to bio-terrorism. The constructed evaluation system was consisted of five first-class and 16 second-class indexes. Among them, medical response factor was considered as the most important factor with weight coefficient of 0.660, followed in turn by the emergency management factor with weight coefficient of 0.109, emergency management consciousness factor with weight coefficient of 0.093, hardware support factor with weight coefficient of 0.078, and improvement factor with weight coefficient of 0.059. The constructed comprehensive assessment model and system are scientific and practical.

  1. Comprehensive Locoregional Treatment and Systemic Therapy for Postmastectomy Isolated Locoregional Recurrence

    International Nuclear Information System (INIS)

    Kuo, S.-H.; Huang, C.-S.; Kuo, W.-H.; Cheng, A.-L.; Chang, K.-J.; Chia-Hsien Cheng, Jason

    2008-01-01

    Purpose: To assess the impact of comprehensive locoregional therapy and systemic therapy on disease control and survival for postmastectomy patients with isolated locoregional recurrence (ILRR). Methods and Materials: A total of 115 postmastectomy breast cancer patients treated for ILRR were included. Of the patients, 98 underwent comprehensive locoregional treatment (local tumor excision plus postoperative radiotherapy), and 17 received definitive radiotherapy alone. Involved-field radiotherapy was given to 69 patients, whereas entire-field radiotherapy (both involved-field and elective-field, involving the chest wall and regional lymphatics) was given to 46 patients. Systemic therapy consisting of hormone therapy, chemotherapy, or both was given to 69% of patients. Results: Patients treated with comprehensive locoregional treatment had a significantly better 5-year invasive disease-free survival (IDFS) and overall survival (OS) after ILRR than patients treated with definitive radiotherapy alone (IDFS rate, 51% vs. 16%, p = 0.006; OS rate, 62% vs. 37%, p = 0.017). Patients with the most comprehensive locoregional treatment (recurrent tumor excision and entire-field radiotherapy) and systemic therapy had a significantly better 5-year IDFS and OS than patients given either treatment or neither treatment (IDFS rate, 52% vs. 39%, p = 0.011; OS rate, 63% vs. 50%, p = 0.026). Multivariate analysis revealed that positive axillary lymph nodes, Grade III tumor, negative estrogen and progesterone receptor status at primary diagnosis, disease-free interval of less than 2 years, and less comprehensive locoregional treatment were significantly associated with worse IDFS and OS. Conclusions: Use of comprehensive locoregional therapy and systemic therapy can achieve good survival outcome in a substantial proportion of postmastectomy patients with ILRR

  2. Research on comprehensive decision-making of PV power station connecting system

    Science.gov (United States)

    Zhou, Erxiong; Xin, Chaoshan; Ma, Botao; Cheng, Kai

    2018-04-01

    In allusion to the incomplete indexes system and not making decision on the subjectivity and objectivity of PV power station connecting system, based on the combination of improved Analytic Hierarchy Process (AHP), Criteria Importance Through Intercriteria Correlation (CRITIC) as well as grey correlation degree analysis (GCDA) is comprehensively proposed to select the appropriate system connecting scheme of PV power station. Firstly, indexes of PV power station connecting system are divided the recursion order hierarchy and calculated subjective weight by the improved AHP. Then, CRITIC is adopted to determine the objective weight of each index through the comparison intensity and conflict between indexes. The last the improved GCDA is applied to screen the optimal scheme, so as to, from the subjective and objective angle, select the connecting system. Comprehensive decision of Xinjiang PV power station is conducted and reasonable analysis results are attained. The research results might provide scientific basis for investment decision.

  3. Comprehensive evaluation index system of total supply capability in distribution network

    Science.gov (United States)

    Zhang, Linyao; Wu, Guilian; Yang, Jingyuan; Jia, Shuangrui; Zhang, Wei; Sun, Weiqing

    2018-01-01

    Aiming at the lack of a comprehensive evaluation of the distribution network, based on the existing distribution network evaluation index system, combined with the basic principles of constructing the evaluation index, put forward a new evaluation index system of distribution network capacity. This paper is mainly based on the total supply capability of the distribution network, combining single index and various factors, into a multi-evaluation index of the distribution network, thus forming a reasonable index system, and various indicators of rational quantification make the evaluation results more intuitive. In order to have a comprehensive judgment of distribution network, this paper uses weights to analyse the importance of each index, verify the rationality of the index system through the example, it is proved that the rationality of the index system, so as to guide the direction of distribution network planning.

  4. Toward a Comprehensive Model of Antisocial Development: A Dynamic Systems Approach

    Science.gov (United States)

    Granic, Isabela; Patterson, Gerald R.

    2006-01-01

    The purpose of this article is to develop a preliminary comprehensive model of antisocial development based on dynamic systems principles. The model is built on the foundations of behavioral research on coercion theory. First, the authors focus on the principles of multistability, feedback, and nonlinear causality to reconceptualize real-time…

  5. An Analysis and Allocation System for Library Collections Budgets: The Comprehensive Allocation Process (CAP)

    Science.gov (United States)

    Lyons, Lucy Eleonore; Blosser, John

    2012-01-01

    The "Comprehensive Allocation Process" (CAP) is a reproducible decision-making structure for the allocation of new collections funds, for the reallocation of funds within stagnant budgets, and for budget cuts in the face of reduced funding levels. This system was designed to overcome common shortcomings of current methods. Its philosophical…

  6. "Teaching Case": ComprehensiveCare and the Failed Implementation of an Electronic Health Records System

    Science.gov (United States)

    Gomillion, David L.

    2017-01-01

    Administrator Jennifer Stanton attempts to adopt an Electronic Health Records system at ComprehensiveCare, a multispecialty healthcare practice. Consultants from the vendor provide guidance to the organization, but do not provide that guidance in a way that the non-technical administrator understands. The project experiences escalation of…

  7. Promoting Information Systems Major to Undergraduate Students--A Comprehensive Investigation

    Science.gov (United States)

    Li, Lei; Zhang, Chi; Zheng, Guangzhi

    2014-01-01

    Weak enrollment growth has been a concern for many Information Systems (IS) programs in recent years although the IT/IS job market remains strong. Stimulating undergraduate students' interest to IS programs have been a challenge. In this paper, the researchers took a comprehensive approach to study how to effectively promote a Management…

  8. School Segregation and Its Effects on Educational Equality and Efficiency in 16 OECD Comprehensive School Systems

    Science.gov (United States)

    Benito, Ricard; Alegre, Miquel Àngel; Gonzàlez-Balletbò, Isaac

    2014-01-01

    Using PISA data for 16 Western OECD countries having comprehensive school systems, we explore the conditions under which the socioeconomic composition of schools affects educational efficiency and equality, to a greater or lesser extent. First, a multilevel analysis is applied to examine and compare the effect of school socioeconomic composition…

  9. Comprehensive Adult Student Assessment Systems Braille Reading Assessment: An Exploratory Study

    Science.gov (United States)

    Posey, Virginia K.; Henderson, Barbara W.

    2012-01-01

    Introduction: This exploratory study determined whether transcribing selected test items on an adult life and work skills reading test into braille could maintain the same approximate scale-score range and maintain fitness within the item response theory model as used by the Comprehensive Adult Student Assessment Systems (CASAS) for developing…

  10. Design of comprehensive general maintenance service system of aerial reconnaissance camera

    Directory of Open Access Journals (Sweden)

    Li Xu

    2016-01-01

    Full Text Available Aiming at the problem of lack of security equipment for airborne reconnaissance camera and universal difference between internal and external field and model, the design scheme of comprehensive universal system based on PC-104 bus architecture and ARM wireless test module is proposed is proposed using the ATE design. The scheme uses the "embedded" technology to design the system, which meets the requirements of the system. By using the technique of classified switching, the hardware resources are reasonably extended, and the general protection of the various types of aerial reconnaissance cameras is realized. Using the concept of “wireless test”, the test interface is extended to realize the comprehensive protection of the aerial reconnaissance camera and the field. The application proves that the security system works stably, has good generality, practicability, and has broad application prospect.

  11. Fuzzy comprehensive evaluation for grid-connected performance of integrated distributed PV-ES systems

    Science.gov (United States)

    Lv, Z. H.; Li, Q.; Huang, R. W.; Liu, H. M.; Liu, D.

    2016-08-01

    Based on the discussion about topology structure of integrated distributed photovoltaic (PV) power generation system and energy storage (ES) in single or mixed type, this paper focuses on analyzing grid-connected performance of integrated distributed photovoltaic and energy storage (PV-ES) systems, and proposes a comprehensive evaluation index system. Then a multi-level fuzzy comprehensive evaluation method based on grey correlation degree is proposed, and the calculations for weight matrix and fuzzy matrix are presented step by step. Finally, a distributed integrated PV-ES power generation system connected to a 380 V low voltage distribution network is taken as the example, and some suggestions are made based on the evaluation results.

  12. Integrated Comprehensive Care - A Case Study in Nursing Leadership and System Transformation.

    Science.gov (United States)

    Wheatley, Laura; Doyle, Winnie; Evans, Cheryl; Gosse, Carolyn; Smith, Kevin

    2017-01-01

    Calls for transformational change of our healthcare system are increasingly clear, persuasive and insistent. They resonate at all levels, with those who fund, deliver, provide and receive care, and they are rooted in a deep understanding that the system, as currently rigidly structured, most often lacks the necessary flexibility to comprehensively meet the needs of patients across the continuum of care. The St. Joseph's Health System (SJHS) Integrated Comprehensive Care (ICC) Program, which bundles care and funding across the hospital to home continuum, has reduced fragmentation of care, and it has delivered improved outcomes for patients, providers and the system. This case study explores the essential contribution of nursing leadership to this successful transformation of healthcare service delivery.

  13. A Comprehensive Rehabilitation Approach in a Patient With Serious Neuropsychiatric Systemic Lupus Erythematosus.

    Science.gov (United States)

    Ko, Yong Jae; Lee, Yang Gyun; Park, Ji Woong; Ahn, Sung Ho; Kwak, Jin Myoung; Choi, Yoon-Hee

    2016-08-01

    Neuropsychiatric systemic lupus erythematosus (NPSLE) involves the central and peripheral nervous system in patients with systemic lupus erythematosus (SLE). It is essential to specify the problems faced by patients with NPSLE because it causes diverse disabilities and impairs quality of life. After performing a comprehensive evaluation, tailored management should be provided for the patient's specific problems. We report here the case of a 30-year-old female with SLE who experienced serious neuropsychiatric symptoms cerebral infarction followed by posterior reversible encephalopathy syndrome and peripheral polyneuropathy. We systemically assessed the patient using the International Classification of Functioning, Disability and Health model as a clinical problem-solving tool and provided comprehensive rehabilitation by focusing on her problems.

  14. Assessing Viability and Sustainability: a Systems-based Approach for Deriving Comprehensive Indicator Sets

    Directory of Open Access Journals (Sweden)

    Hartmut Bossel

    2002-01-01

    Full Text Available Performance assessment in holistic approaches such as integrated natural resource management has to deal with a complex set of interacting and self-organizing natural and human systems and agents, all pursuing their own "interests" while also contributing to the development of the total system. Performance indicators must therefore reflect the viability of essential component systems as well as their contributions to the viability and performance of other component systems and the total system under study. A systems-based derivation of a comprehensive set of performance indicators first requires the identification of essential component systems, their mutual (often hierarchical or reciprocal relationships, and their contributions to the performance of other component systems and the total system. The second step consists of identifying the indicators that represent the viability states of the component systems and the contributions of these component systems to the performance of the total system. The search for performance indicators is guided by the realization that essential interests (orientations or orientors of systems and actors are shaped by both their characteristic functions and the fundamental and general properties of their system environments (e.g., normal environmental state, scarcity of resources, variety, variability, change, other coexisting systems. To be viable, a system must devote an essential minimum amount of attention to satisfying the "basic orientors" that respond to the properties of its environment. This fact can be used to define comprehensive and system-specific sets of performance indicators that reflect all important concerns. Often, qualitative indicators and the study of qualitative systems are sufficient for reliable performance assessments. However, this approach can also be formalized for quantitative computer-assisted assessment. Examples are presented of indicator sets for the sustainable development of

  15. Comprehensive Maintenance of CCTV System at Bangi Complex, Malaysian Nuclear Agency

    International Nuclear Information System (INIS)

    Hasif Mohamad; Mohd Hazri Mohd Salleh; Mohd Ghazali Bachol

    2015-01-01

    Control of Closed Circuit Camera (CCTV) is a security monitoring system used to monitor an area using the method of monitoring of video. The use of CCTV allows the operator to monitor the area that has been equipped with CCTV cameras from a control center is provided. CCTV system has proved effective in terms of facilitating the task of monitoring, save costs, and improves safety. Recognizing the high requirements to ensure the system is running without interruption, the PIA has implemented a comprehensive maintenance program on all CCTV complex is located in Bangi, Malaysia Nuclear Agency at a cost of RM 95,000.00 for the year. This paper will report on the implementation of a comprehensive maintenance contract CCTV and discuss the problems faced during the contract period. (author)

  16. Comprehensive Maintenance of CCTV System at Bangi Complex Malaysian Nuclear Agency

    International Nuclear Information System (INIS)

    Hasif Mohamad; Mohd Hazri Mohd Salleh; Mohd Ghazali Bachol

    2015-01-01

    Control of Closed Circuit Camera (CCTV) is a security monitoring system used to monitor an area using the method of monitoring of video. The use of CCTV allows the operator to monitor the area that has been equipped with CCTV cameras from a control center is provided. CCTV system has proved effective in terms of facilitating the task of monitoring, save costs, and improves safety. Recognizing the high requirements to ensure the system is running without interruption, the PIA has implemented a comprehensive maintenance program on all CCTV complex is located in Bangi, Malaysia Nuclear Agency at a cost of RM 95,000.00 for the year. This paper will report on the implementation of a comprehensive maintenance contract CCTV and discuss the problems faced during the contract period. (author)

  17. Overview on Environmental Comprehensive Management System Established in Imitation of Biome

    Institute of Scientific and Technical Information of China (English)

    李如燕; 孙可伟

    2004-01-01

    Environmental comprehensive management system, called "the bionic community", can be established in imitation of biome, which can transform the wastes generated in a certain field into the raw materials of other field. The establishment of the bionic community includes two aspects, i.e. , the matching technique and the management system. The main matching technique is the preparation of composite materials made of various wastes.This new kind of material can be divided into four types: polymer matrix, silicate matrix, metal matrix and carbon matrix (or ceramic matrix). The environmental comprehensive management system is formed by organizing a transtrades joint-management business entity with the products of composite material made of wastes at the core.

  18. A study on regional comprehensive performance evaluation indicator system of rational use of drugs

    Directory of Open Access Journals (Sweden)

    Sun Tongda

    2017-01-01

    Full Text Available The current research presents the design of a 4-degree-3-level performance evaluation indicator system of rational use of drugs for health care institutions accord with the Balanced Score Card (BSC method. Financial index, patient index, professional process index, and development and blazing new trials index are adopted in the light of scientific, guiding, operable and generalizable principles. The index weight is based on the analytic hierarchy process, and comprehensive performance evaluation indicators are calculated by a linear integrated weighting method. Its practical application in 21 state-run health care institutions in Ningbo, from 2008 to 2012, has arrived at the finding that the comprehensive performance evaluation indicator system offers a scientific, practical and effective performance management quantification and is thus worth popularizing.

  19. Evaluating energy saving system of data centers based on AHP and fuzzy comprehensive evaluation model

    Science.gov (United States)

    Jiang, Yingni

    2018-03-01

    Due to the high energy consumption of communication, energy saving of data centers must be enforced. But the lack of evaluation mechanisms has restrained the process on energy saving construction of data centers. In this paper, energy saving evaluation index system of data centers was constructed on the basis of clarifying the influence factors. Based on the evaluation index system, analytical hierarchy process was used to determine the weights of the evaluation indexes. Subsequently, a three-grade fuzzy comprehensive evaluation model was constructed to evaluate the energy saving system of data centers.

  20. A comprehensive inversion approach for feedforward compensation of piezoactuator system at high frequency

    Science.gov (United States)

    Tian, Lizhi; Xiong, Zhenhua; Wu, Jianhua; Ding, Han

    2016-09-01

    Motion control of the piezoactuator system over broadband frequencies is limited due to its inherent hysteresis and system dynamics. One of the suggested ways is to use feedforward controller to linearize the input-output relationship of the piezoactuator system. Although there have been many feedforward approaches, it is still a challenge to develop feedforward controller for the piezoactuator system at high frequency. Hence, this paper presents a comprehensive inversion approach in consideration of the coupling of hysteresis and dynamics. In this work, the influence of dynamics compensation on the input-output relationship of the piezoactuator system is investigated first. With system dynamics compensation, the input-output relationship of the piezoactuator system will be further represented as rate-dependent nonlinearity due to the inevitable dynamics compensation error, especially at high frequency. Base on this result, the feedforward controller composed by a cascade of linear dynamics inversion and rate-dependent nonlinearity inversion is developed. Then, the system identification of the comprehensive inversion approach is proposed. Finally, experimental results show that the proposed approach can improve the performance on tracking of both periodic and non-periodic trajectories at medium and high frequency compared with the conventional feedforward approaches.

  1. Managing Intellectual Property Rights Protection in the System of Comprehensive Seconday Education

    Directory of Open Access Journals (Sweden)

    Vadim Lunyachek

    2018-05-01

    Full Text Available This paper provides the results of the survey conducted among the teachers and principals of comprehensive secondary schools of Kharkiv as to their awareness of how to abide by, draw up and defend intellectual property rights. The paper suggests implementing a system of actions to further the qualifications of educators in this area by introducing relevant special courses, delivering lectures and workshops, or obtaining a second higher education degree.

  2. DESIGN MODELING OF A UNIVERSITY’S COMPREHENSIVE-INTEGRATED SECURITY SYSTEM

    Directory of Open Access Journals (Sweden)

    Marina V. Dulyasova

    2017-03-01

    Full Text Available Introduction: the safety of higher education institutions is considered to be of great importance nowadays. Security challenges need to be addressed through a comprehensive and integrative approach. This approach provides neutralisation of various threats systemically, risk prevention, minimisation of the tangible and moral harm. The project concept of “safe university” is proposed and substantiated for the above-mentioned purposes. Materials and Methods: the authors used a special literature survey on the issue, which is divided into three main groups of publications, where the complex security of educational institutions is considered in the context of the general theory of security, in the educational-methodical plan and within the framework of sociological, psychological and pedagogical approaches. The legislative and regulatory sources also indicated, legislative and regulatory legal acts reviews, “Safe City” concept, National standard “Information security technologies: complex and integrated ones. Standard requirements to architecture and technologies of intellectual systems of monitoring for safety of the companies and the territories” (State standard specification P 56875-2016, documents of higher education institutions, media reports. The analysis and generalisation of information was coupled with project modeling of the new comprehensive system of higher education institution security. Results: the authors introduce the concept, architecture and model of the comprehensive integrated higher education institution security, monitoring based on measures and indicators pertaining to implementation of standard requirements and level of satisfaction with safety, evaluation of the taken measures in terms of efficiency. Discussion and Conclusions: the main contours of the model for comprehensive integrated security system in a higher education institution and algorithm of interaction between the subjects are determined. These

  3. A Study on improvement of comprehensive environmental management system - activation of liberalized environmental management

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Hweu Sung; Kang, Chul Goo [Korea Environment Institute, Seoul (Korea)

    1998-12-01

    As a part of improvement on a comprehensive environmental management system, this study was attempted to find an activating policy for a liberalized environmental management. This study provided an activation plan of reasonable environmental regulation reform and liberalized environmental management through the analysis of foreign examples and domestic situation. Furthermore, it analyzed an institutional mechanism for a smooth operation of liberalized environmental management. 68 refs., 5 figs., 51 tabs.

  4. A comprehensive operating room information system using the Kinect sensors and RFID.

    Science.gov (United States)

    Nouei, Mahyar Taghizadeh; Kamyad, Ali Vahidian; Soroush, Ahmad Reza; Ghazalbash, Somayeh

    2015-04-01

    Occasionally, surgeons do need various types of information to be available rapidly, efficiently and safely during surgical procedures. Meanwhile, they need to free up hands throughout the surgery to necessarily access the mouse to control any application in the sterility mode. In addition, they are required to record audio as well as video files, and enter and save some data. This is an attempt to develop a comprehensive operating room information system called "Medinav" to tackle all mentioned issues. An integrated and comprehensive operating room information system is introduced to be compatible with Health Level 7 (HL7) and digital imaging and communications in medicine (DICOM). DICOM is a standard for handling, storing, printing, and transmitting information in medical imaging. Besides, a natural user interface (NUI) is designed specifically for operating rooms where touch-less interactions with finger and hand tracking are in use. Further, the system could both record procedural data automatically, and view acquired information from multiple perspectives graphically. A prototype system is tested in a live operating room environment at an Iranian teaching hospital. There are also contextual interviews and usability satisfaction questionnaires conducted with the "MediNav" system to investigate how useful the proposed system could be. The results reveal that integration of these systems into a complete solution is the key to not only stream up data and workflow but maximize surgical team usefulness as well. It is now possible to comprehensively collect and visualize medical information, and access a management tool with a touch-less NUI in a rather quick, practical, and harmless manner.

  5. NeuroVRAC--a comprehensive approach to virtual reality-based neurological assessment and treatment systems.

    Science.gov (United States)

    Valvoda, Jakob T; Assenmacher, Ingo; Dohle, Christian; Kuhlen, Torsten; Bischof, Christian

    2003-01-01

    We describe a comprehensive software-oriented approach to virtual reality-based neuroscientific systems in order to establish an easy to use framework for neuroscientific assessment and treatment. We have defined a process model and implemented the NeuroVRAC authoring tool for design and execution of experiments in virtual environments. Our system enables the modeling of virtual world objects and the definition of events, which are used to control the experimental process. We have included the virtual test person concept to enhance the sense of presence during the execution of virtual reality-based neuroscientific experiments.

  6. THE ANALYSIS OF THE COMPREHENSIVE INSURANCE DEMAND FOR TURKEY USING UTILITY THEORY AND SYSTEM SIMULATION

    Directory of Open Access Journals (Sweden)

    Murat KIRKAĞAÇ

    2017-03-01

    Full Text Available In this study, the demand for comprehensive insurance is analysed using utility theory and system simulation. A simulation study is performed to assess the behaviour of individuals with different income levels for the demand of comprehensive insurance. Simulation assumptions and input-output variables are determined using the real data set from a Turkish insurance company and the report about the insurance activities in Turkey for year 2014. The effects of income level, expected claim severity and premium level on the demand for insurance are investigated. It is concluded that while an increase in income level and expected claim severity causes an increase in the demand, an increase in premium level causes a decrease in the demand.

  7. The Comprehensive Assessment List for Affective Disorders (COALA): a polydiagnostic, comprehensive, and serial semistructured interview system for affective and related disorders.

    Science.gov (United States)

    Furukawa, T; Takahashi, K; Kitamura, T; Okawa, M; Miyaoka, H; Hirai, T; Ueda, H; Sakamoto, K; Miki, K; Fujita, K

    1995-01-01

    This supplement describes the development and structure of the Comprehensive Assessment List of Affective Disorders (COALA) system, which was recently developed for a collaborative follow-up study of a broad spectrum of affective disorders in Japan and which consists of a series of semistructured interviews for affective and related disorders. The COALA distinguishes itself from the extant semistructured interviews by being able to provide polydiagnostic, comprehensive and serial assessments. It is polydiagnostic because it derives diagnoses according to 29 historical and modern diagnostic systems through computer algorithms. It is comprehensive because it not only depicts the symptoms profile and rates their severity according to various endogenicity indices and severity rating scales but also measures, in the psychosocial domain, the life events and their characteristics. In addition, it has sections for past illnesses and family history. It is serial because the system includes follow-up semistructured interviews that can be administered monthly and that monitor changes in the psychopathological and psychosocial features. The theoretical underpinnings of the COALA system, especially its polydiagnostic approach to a broad spectrum of affective disorders and its treatment of psychosocial factors, are discussed in view of recent proposals for the future nosological research. The findings of the interrater reliability study (n = 107) are also presented, with satisfactory to excellent results for almost all of the psychopathological and psychosocial variables, all of the composite severity ratings and most of the polydiagnostic evaluations.

  8. Comprehensive Benefit Evaluation of the Wind-PV-ES and Transmission Hybrid Power System Consideration of System Functionality and Proportionality

    Directory of Open Access Journals (Sweden)

    Huizheng Ji

    2017-01-01

    Full Text Available In the background of decreasing fossil fuels and increasing environmental pollution, the wind-photovoltaic energy storage and transmission hybrid power system (or called the wind-PV-ES and transmission hybrid system has become a strategic choice to achieve energy sustainability. However, the comprehensive benefit evaluation of such a combined power system is in a relatively blank state in China, which will hinder the reasonable and orderly development of this station. Four parts, the technical performance, economic benefit, ecological impact and social benefit, are considered in this paper, and a multi-angle evaluation index system of the wind-PV-ES and transmission system is designed. The projection pursuit model is used to evaluated system functionality conventionally; relative entropy theory is used to evaluate the system functionality simultaneously; and a comprehensive benefit evaluation model of the technique for order preference by similar to ideal solution (TOPSIS considering both system functionality and proportionality is constructed. Finally, the national demonstration station of the wind-PV-ES-transmission system is taken as an example to testify to the practicability and validity of the evaluation index system and model.

  9. The Effect of a Course Management System (CMS)-Supported Strategy Instruction on EFL Reading Comprehension and Strategy Use

    Science.gov (United States)

    Tsai, Yea-Ru; Talley, Paul C.

    2014-01-01

    This paper reports on the effect of a Moodle-supported strategy instruction on both reading comprehension and strategy use among EFL (English as a Foreign Language) students. Specific reading strategy training was first integrated into a Moodle system, which included reading exercises on problem identification, monitoring comprehension,…

  10. Development of comprehensive care system for children with autism syndrome disorders in Russia: one project experience

    Directory of Open Access Journals (Sweden)

    Alekhina S.V.

    2016-12-01

    Full Text Available Attention to the issue of children with ASD in our country is growing steadily. Since the release of the new Law «About the education in Russian Federation», where for the first time this category of children was secured by state guarantees, all normative acts and basic solutions are focused on the development of comprehensive care for children with ASD and their families. Official initiatives are in many ways supported with the activity of community organizations and parental associations, representing the interests of families. Experience of many years becomes the basis for efficient solutions and social problems analysis of the identification, education and support of people with autism. Also it becomes platform for social and psychological support of their families. Currently, in the Russian Federation, domestic model for providing comprehensive medical and social, psychological and educational assistance for children with autism just begin to develop. However, the policy, conducted by the government for individuals with disabilities, including children with ASD, confirms state structures readiness to take the main measures of comprehensive rehabilitation and habilitation. The article describes the experience of creating integrated care systems for children with ASD in Russia. The example of project real¬ization involving three of the Russian Federation states, which is aimed at ensuring high quality of life of children, is shown

  11. The need for a comprehensive energy management information system for industries

    Directory of Open Access Journals (Sweden)

    Goosen, P

    2016-11-01

    Full Text Available Electricity costs in South Africa are increasing rapidly, and the funding hurdle rates for energy conservation incentives are decreasing. Therefore, with rising international competition and increasing operational costs, marginal industries need to focus on energy management strategies where larger savings can be achieved with lower capital expenditure. This paper sketches the need for a comprehensive energy management information system (EMIS. Common industrial energy management pitfalls are identified and energy conservation incentives are outlined. New focus points that improve client awareness and in turn improve the sustainability of energy management interventions are also highlighted. However, benefitting from energy incentives is becoming more complex. Therefore, many clients do not benefit from these incentives unless specialised Energy Service Companies (ESCos are employed. ESCos, however, require large amounts of data to manage clients’ energy effectively. Herein lies the need for a comprehensive EMIS that aids ESCos and their clients with the energy management process. An EMIS was developed and implemented for several industries in South Africa. Data is automatically collected, processed, analysed, and presented on a daily basis. A case study investigates the exorbitant amounts of data and reports that are managed automatically, which further highlights the need for a comprehensive EMIS.

  12. Development of comprehensive unattended child warning and feedback system in vehicle

    Directory of Open Access Journals (Sweden)

    Sulaiman Norizam

    2017-01-01

    Full Text Available The cases of children being trapped and suffocated in unattended vehicle keep increasing even though the awareness campaign on the safety of children in non-moving vehicle were carried out by government. Various methods were introduced by researchers to overcome this issue but yet to be effective. Among them were the usage of capacitive sensor, microwave sensor, pressure sensor and image sensor where most of the techniques or systems were applied on the child’s seat to detect the presence of baby or infant. Thus, this research is carried out to provide a comprehensive and effective detection system to detect the presence of children including infant in unattended vehicle by using the combination of human physiological signals (voice and body odor detectors with the temperature and motion sensors. Here, once the proposed system recognizes any signals that generated from voice, odor, motion and temperature detectors in vehicle’s cabin, the system then will provide effective feedback system by sending short message to the parents first. If no response received in the specified allocation time, the system then will activate the vehicle’s horn system. Finally, the system will lower down the vehicle’s window to release the toxic gas and reduce the cabin temperature. The system is in prototyping stage where every design component was evaluated individually. Besides, the overall system was successfully tested where the detection and feedback system follow the instruction given by the microcontroller.

  13. Challenges in developing a comprehensive, automated and flexible oil accounting system

    Energy Technology Data Exchange (ETDEWEB)

    Nordell, L.F.; Ruda, H. [Enbridge Pipelines Inc., Edmonton, AB (Canada)

    2004-07-01

    Enbridge Pipelines Inc. operates a long and complex system of pipelines which transport hydrocarbon liquid commodities, including crude oils, refined products and natural gas liquids across provincial and national boundaries. Due to growing internal demands for the addition of pipelines, the company developed a comprehensive oil accounting (OA) system in 1998. The OA accommodated changing business requirements by incorporating more complex tariff agreements and the demand for customized system reporting for customers. The new OA was also compatible with the company's technology direction, which focused on aligning information technology (IT) with business drivers and upgrading the flexibility of the entire OA system. This paper summarized the business improvement and redevelopment study; the OA system redevelopment project; challenges of integrating new system components with the legacy system during system development; specific process improvement results that were targeted and achieved by the new system development team; and, the project development challenges. The project team adopted a software development approach that was responsive to changes in the requirements and in the project direction introduced by key stakeholders during the life of the project. The project management approaches and logic of the SCRUM and extreme programming (XP) methods were combined to incorporate the principles of agile development to ensure a quality product. The result was an automated crude oil balancing and revenue accounting system that interfaced with other pipeline management software systems. 6 refs., 5 figs.

  14. Comprehensive allelotype and genetic anaysis of 466 human nervous system tumors

    DEFF Research Database (Denmark)

    von Deimling, A; Fimmers, R; Schmidt, M C

    2000-01-01

    Brain tumors pose a particular challenge to molecular oncology. Many different tumor entities develop in the nervous system and some of them appear to follow distinct pathogenic routes. Molecular genetic alterations have increasingly been reported in nervous system neoplasms. However......, a considerable number of affected genes remain to be identified. We present here a comprehensive allelotype analysis of 466 nervous system tumors based on loss of heterozygosity (LOH) studies with 129 microsatellite markers that span the genome. Specific alterations of the EGFR, CDK4, CDKN2A, TP53, DMBT1, NF2...... may provide a valuable framework for future studies to delineate molecular pathways in many types of human central nervous system tumors....

  15. Measuring the immune system: a comprehensive approach for the analysis of immune functions in humans.

    Science.gov (United States)

    Claus, Maren; Dychus, Nicole; Ebel, Melanie; Damaschke, Jürgen; Maydych, Viktoriya; Wolf, Oliver T; Kleinsorge, Thomas; Watzl, Carsten

    2016-10-01

    The immune system is essential to provide protection from infections and cancer. Disturbances in immune function can therefore directly affect the health of the affected individual. Many extrinsic and intrinsic factors such as exposure to chemicals, stress, nutrition and age have been reported to influence the immune system. These influences can affect various components of the immune system, and we are just beginning to understand the causalities of these changes. To investigate such disturbances, it is therefore essential to analyze the different components of the immune system in a comprehensive fashion. Here, we demonstrate such an approach which provides information about total number of leukocytes, detailed quantitative and qualitative changes in the composition of lymphocyte subsets, cytokine levels in serum and functional properties of T cells, NK cells and monocytes. Using samples from a cohort of 24 healthy volunteers, we demonstrate the feasibility of our approach to detect changes in immune functions.

  16. Comprehensive Modelling and Simulation System for Decision Support in the Field of Radiation Potection

    Czech Academy of Sciences Publication Activity Database

    Pecha, Petr; Hofman, Radek

    -, č. 81 (2010), s. 17-18 ISSN 0926-4981 R&D Projects: GA MŠk(CZ) 1M0572; GA ČR(CZ) GA102/07/1596 Institutional research plan: CEZ:AV0Z10750506 Keywords : decision support * modelling * radiation protection * environmental impact assessment * probability safety assessment Subject RIV: JF - Nuclear Energetics http://library.utia.cas.cz/separaty/2010/AS/pecha-comprehensive modelling and simulation system for decision support in the field of radiation potection.pdf

  17. Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis

    Energy Technology Data Exchange (ETDEWEB)

    Karger, Barry L.; Kotler, Lev; Foret, Frantisek; Minarik, Marek; Kleparnik, Karel

    2003-12-09

    A modular multiple lane or capillary electrophoresis (chromatography) system that permits automated parallel separation and comprehensive collection of all fractions from samples in all lanes or columns, with the option of further on-line automated sample fraction analysis, is disclosed. Preferably, fractions are collected in a multi-well fraction collection unit, or plate (40). The multi-well collection plate (40) is preferably made of a solvent permeable gel, most preferably a hydrophilic, polymeric gel such as agarose or cross-linked polyacrylamide.

  18. New Methodology for a Comprehensive Modular Safety Control System in a Cyclotron Site

    International Nuclear Information System (INIS)

    Kaufman, Y.; Kravitz, M.; Arad, M.; Osovizky, A.; Paran, J.; Sarussi, B.; Ellenbogen, M.; Tal, N.

    2004-01-01

    This Paper describes a new methodology for a comprehensive modular Safety Control System (SCS), for a cyclotron site. The developed SCS is a modular approach for controlling the production procedures, safety conditions and documentation aspects in the Cyclotron site. Usually, the safety conditions in cyclotron sites are maintained by a variety of sensors. The cyclotron is supplied from the manufacturer with a self-integrated control system for its operation, yet the comprehensive SCS has to be defined and setup by the customer. Therefore, customers face a lot of integration problems in trying to combine all the signals from the different safety systems such as radiation monitoring, environmental and access control, in order to maintain proper safety working conditions. The presented SCS design provides main user interface and the complete safety solution required by including preset control logic definitions and open logic for specific user applications. The knowledge for the preset control logic definitions was gathered in previous projects. Failure Mode and Effects Analysis (FMEA) method has been implemented on the SCS to analyze the potential failure modes and their impact on the product reliability

  19. Comprehensive nuclear counting and detector characterisation system for the radiochemistry laboratory

    International Nuclear Information System (INIS)

    Parthasarathy, R.; Saisubalakshmi, D.; Mishra, G.K.; Srinivas, K.C.; Venkatasubramani, C.R.

    2004-01-01

    The paper describes a comprehensive nuclear pulse counting system that can cater to up to seven nuclear detector set-ups located in different places in the laboratory. Each detector set up has an interfacing module that conditions the amplifier pulses and transmits them to a common counting system. The microcontroller-based system receives these pulses through a multiplexer and counts the pulses for a user specified preset time. The system has a routine to determine detector plateau characteristics and fix the detector operating voltage. In this mode, the system collects the EHT-versus- counts data in a EHT programmed sequence and plots the profile. The system conducts the counting routine for a stipulated number of times and does all necessary statistical tests to ensure the proper functioning of the detector under test. The system also includes a test routine that checks the performance of the counting system by connecting it to a local pulse generator. The microcontroller based system interacts with a PC through RS232 communication for user interaction and reporting. (author)

  20. Form Quality in Rorschach Comprehensive System and R-PAS: Sample of Psychiatric Cases

    Directory of Open Access Journals (Sweden)

    Latife Yazigi

    2016-04-01

    Full Text Available Abstract The creation of the Rorschach Performance Assessment System (R-PAS requires research that allows its use in the Brazilian population. The Formal Quality (FQ category is essential both for clinic and research. The aim of this study was to compare form quality variables in Rorschach protocols from psychiatric patients and ratings coded in the Comprehensive System (CS and R-PAS. The sample comprised 206 Rorschach protocols from adult patients in psychiatric treatment, who were also assessed by SCID-I and SCID-II. Most protocols were administered in the CS and recoded according to the R-PAS. The kappa coefficient was calculated, and we compared the means of these variables in both systems. The kappa results varied from almost perfect to substantial consistency for all variables, however, the descriptive statistics confirmed that the R-PAS elicits more FQ Ordinary coding while the CS elicits more FQ minus coding.

  1. The comprehensiveness of environmental management systems: The influence of institutional pressures and the impact on environmental performance.

    Science.gov (United States)

    Phan, Thanh Nguyet; Baird, Kevin

    2015-09-01

    This study contributes to the EMS literature by providing a more detailed insight into the comprehensiveness of environmental management systems (EMSs) by focusing on the intensity of use of environmental management practices. In addition, the study examines the influence of institutional pressures (coercive, mimetic and normative) on the comprehensiveness of environmental management systems (EMSs), and the impact of EMS comprehensiveness on environmental performance. A mail survey questionnaire was used to collect data from a random sample of Australian senior managers across various industries. Both coercive and normative pressures were found to influence the comprehensiveness of EMSs. Specifically, the pressure exerted by the government, through the creation of appropriate regulatory pressures and public incentives, and by employees, customers, professional groups, the media, and community, influenced the comprehensiveness of the EMS. In addition, organisations with more comprehensive EMSs were found to experience higher levels of environmental performance. With more than 300,000 organisations worldwide adopting EMSs (ISO, 2013), the findings provide an important insight into the relevance of EMSs. In particular, it is suggested that organisations should endeavour to implement a more comprehensive EMS and be conscious of the role that coercive and normative pressures play in influencing the comprehensiveness of their EMSs. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Shenzhen Comprehensive Transport System Planning:An Exploration of Sustainable Urban Transport Development on Condition of Limited Resources

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    With "integration" as the direction,Shenzhen Comprehensive Transport Planning integrates the plan,construction and management of all kinds of transport mode in the transport system,and integrates the transport with the social,economic and environment development.The planning specifies the strategic targets,key indicators,development strategies as well as major policies of the comprehensive transport system,which explores an alternative way for the sustainable urban transport development under the condition of limited resources in Shenzhen.

  3. A comprehensive scoring system in correlation with perioperative airway management for neonatal Pierre Robin Sequence.

    Directory of Open Access Journals (Sweden)

    Ning Yin

    Full Text Available To evaluate a comprehensive scoring system which combines clinical manifestations of Pierre Robin Sequence (PRS including severity of breathing difficulties, body weight and preoperative Cormack-Lehane grade, for its correlation with perioperative PRS airway management decision.Forty PRS children were retrospectively recruited after surgery. Specialists examined all subjects and scored for clinical manifestations (1´ - 4´, weight gain (1´- 4´, dyspnea scores (1´- 4´, and Cormack-Lehane grade (1´- 4´. The correlation of the integrated scores and the necessity of endotracheal intubation or laryngeal mask application were analyzed. In addition, the score correlation with postoperative dyspnea and/or low pulse oxygen saturation (SPO2 levels after extubation was determined.In our study every individual patient had a score from 0´ to 16´, while the higher in the numbers represented higher risk of breathing difficulty. All patients with comprehensive scores 13 points required a laryngeal mask assisted airway management and were considered to have difficult airways. Dyspnea after extubation and postoperative low SPO2 occurred among patients who scored over 10 points.In PRS patients, preoperative weight gaining status and severity of dyspnea in combination with Cormack-Lehane classification provide a scoring system that could help to optimize airway management decisions such as endotracheal intubation or laryngeal mask airway placement and has the potential to predict postoperative dyspnea or low SPO2 levels.

  4. A Concise and Comprehensive Description of Shoulder Pathology and Procedures: The 4D Code System

    Directory of Open Access Journals (Sweden)

    Laurent Lafosse

    2012-01-01

    Full Text Available Background. We introduce a novel description system of shoulder pathoanatomy. Its goal is to provide a comprehensive three-dimensional picture, with an additional component of time; thus, we call it the 4D code. Methods. Each line of the code starts with right versus left and a time designation. The pillar components are recorded regardless of pathology; they include subscapularis, long head of biceps tendon, supraspinatus, infraspinatus, and teres minor. Secondary elements can be added if there is observed pathology, including acromioclavicular joint, glenohumeral joint, labrum, tear configuration, location and extent of partial cuff tear, calcific tendonitis, fatty infiltration, and neuropathy. Results. We provide two illustrative examples of patients which show the ease and effectiveness of the 4D code. With a few simple lines, significant amount of information about patients’ pathology, surgery, and recovery can be easily conveyed. Discussion. We utilize existing validated classification systems for parts of the shoulder and provide a frame work to build a comprehensive picture. The alphanumeric code provides a simple language that is universally understood. The 4D code is concise yet complete. It seeks to improve efficiency and accuracy of the communication, documentation, and visualization of shoulder pathology within individual practices and between providers.

  5. From technical quality assurance of radiotherapy to a comprehensive quality of service management system

    International Nuclear Information System (INIS)

    Kehoe, T.; Rugg, L.

    1999-01-01

    A hierarchy of dosimetry, planning and machine performance checks and evaluations of clinical outcomes have been widely used in radiotherapy for decades. Procedures, codes of practice and guidance are readily available on the technical aspects of radiotherapy treatments, maintenance of which is achieved by quality control checks within a quality assurance approach to radiotherapy. Recently a series of high profile, well-publicised treatment accidents resulting in damage to patients have focused the attention of both professionals and the public. There is now pressure to introduce formal quality management systems. Patients and their relatives/carers are having their expectations raised but their definition of a quality service differs from that generally considered by the oncology professionals. Most departmental managers and staff have wide experience of quality control checks. They understand the philosophy of quality assurance. However the idea of formal quality systems/quality management is alien to them. What is a professional/departmental manager to do? This paper addresses that question by discussing the underlying principles of quality management covering service provision as well as technical radiotherapy treatment delivery and by providing some guidance based on experience in the practical implementation of quality management through three stages of development: a QA programme incorporating checks on essential parts of the technical treatment delivery, a formal documented certified QA system focusing on technical treatment delivery, a comprehensive quality management system covering all parts of a service. One possible action plan is provided indicating progress through the three stages of development based on experience in one large Radiation Oncology Department. With planning, resources and commitment. a comprehensive quality of service management system is achievable in radiotherapy. (author.)

  6. ŽAMPA’S SYSTEMS THEORY: A COMPREHENSIVE THEORY OF MEASUREMENT IN DYNAMIC SYSTEMS

    Directory of Open Access Journals (Sweden)

    Renata Rychtáriková

    2018-04-01

    Full Text Available The article outlines in memoriam Prof. Pavel Žampa’s concepts of system theory which enable us to devise a measurement in dynamic systems independently of the particular system behaviour. From the point of view of Žampa’s theory, terms like system time, system attributes, system link, system element, input, output, sub-systems, and state variables are defined. In Conclusions, Žampa’s theory is discussed together with another mathematical approaches of qualitative dynamics known since the 19th century. In Appendices, we present applications of Žampa’s technical approach to measurement of complex dynamical (chemical and biological systems at the Institute of Complex Systems, University of South Bohemia in České Budějovice.

  7. Design of comprehensive plant information system considering maintenance indicators in nuclear power plant

    International Nuclear Information System (INIS)

    Takata, Takashi; Yamaguchi, Akira; Yamamoto, Akio

    2013-01-01

    A safety of a nuclear power plant must be ensured and maintained through its entire plant life. For this plant life cycle safety (PLCS), a comprehensive plant information system, in which an each maintenance record of the plant is taken into consideration, is of importance. In this paper, a development of a plant chart, which is a part of the information system, has been developed based on a defense-in-depth concept that is one of the most important concept to ensure the plant safety. In the chart, an updated probability of loss of a component or function is used as a maintenance indicator and a probabilistic risk assessment (PRA) method is applied to quantify the plant status in the chart. (author)

  8. Generic dynamic wind turbine models for power system stability analysis: A comprehensive review

    DEFF Research Database (Denmark)

    Honrubia-Escribano, A.; Gómez-Lázaro, E.; Fortmann, J.

    2018-01-01

    In recent years, international working groups, mainly from the International Electrotechnical Commission (IEC) and the Western Electricity Coordinating Council (WECC), have made a major effort to develop generic —also known as simplified or standard— dynamic wind turbine models to be used for power...... system stability analysis. These models are required by power system operators to conduct the planning and operation activities of their networks since the use of detailed manufacturer models is not practical. This paper presents a comprehensive review of the work done in this field, based on the results...... obtained by IEC and WECC working groups in the course of their research, which have motivated the publication of the IEC 61400-27 in February 2015. The final published versions of the generic models developed according to the existing four wind turbine technology types are detailed, highlighting...

  9. The Design and Implementation of Test System Based on Programmable Excitation Power Supply for Mining Comprehensive Protector

    Directory of Open Access Journals (Sweden)

    Zhi-jie Zhang

    2013-11-01

    Full Text Available As comprehensive protectors for coal mining (referred to comprehensive protectors in use are prone to fail, it can timely screen out the invalid comprehensive protector by periodic functional test when it is used (it is called test in use to ensure the production safety. The test in use needs the specialized test equipment, which is not used in delivery inspection by the manufacturers of comprehensive protectors. Thus, testing excitation power becomes a constraint for the improvement of the accuracy of test in use and the degree of automation. To solve the problem, this paper developed a power frequency programmed input-output testing excitation power supply, and on that basis it also realized the mining comprehensive protector test system in use with the excitation circuit and voltage program-controlled output.

  10. Rorschach Comprehensive System data for a sample of 141 adult nonpatients from Denmark.

    Science.gov (United States)

    Ivanouw, Jan

    2007-01-01

    A sample (n = 141) of Danish nonpatients 25-50 years of age, never hospitalized with a psychiatric diagnosis and currently employed, was demographically representative of two geographical areas of Copenhagen with different social strain. The sample, as well as 45 persons not currently employed, was tested with the Rorschach (Exner, 1995), MMPI-2 (Butcher, Dahlstrom, Graham, Tellegen, & Kaemmer, 1989), Word Association Test (Ivanouw, 1999b), WAIS Comprehension subtest (Hess, 1974), and SCL-90-R (Olsen, Mortenson, & Bech, 2006). Half of the persons contacted volunteered for the study. There was no difference in rate of volunteering between a standard no-feedback condition and a feedback condition; the latter, however, tended to attract more psychologically resourceful persons. The employed persons tended to appear healthier than the not employed. Response style of the subjects, quality of the Rorschach protocols, reliability of scoring, and the effect of the data being grouped on geographical area and examiner were examined. Form level, color, texture, cooperative movement, and EA were lower than in the Comprehensive System (CS; n = 450) sample, but higher than in nine international nonpatient Rorschach studies. Unique for the Danish sample was a low number of animal movement answers. The Rorschach data showed women to be healthier than men. Differences in Rorschach variables based on educational level were small.

  11. Application of the nuclide identification system SHAMAN in monitoring the Comprehensive Test Ban Treaty

    International Nuclear Information System (INIS)

    Aarnio, P.A.; Ala-Heikkilae, J.J.; Hakulinen, T.T.; Nikkinen, M.T.

    1998-01-01

    SHAMAN is an expert for qualitative and quantitative radionuclide identification in gamma spectrometry. SHAMAN requires as input the calibrations, peak search, and fitting results from reliable spectral analysis software, such as SAMPO. SHAMAN uses a comprehensive reference library with 2600 radionuclides and 80 000 gamma-lines, as well as a rule base consisting of sixty inference rules. Identification results are presented both via an interactive graphical interface and in the form of configurable text reports. An organization has been established for monitoring the recent Comprehensive Test Ban Treaty. For radionuclide monitoring, 80 stations will be set up around the world. Air-filter gamma-spectra will be collected from these stations on a daily basis and they will need to be reliably analyzed with minimum turnaround time. SHAMAN is currently being evaluated within the prototype monitoring system as an automated radionuclide identifier, in parallel with existing radionuclide identification software. In air-filter monitoring, very low concentrations of radionuclides are measured from bulky sources in close geometry and with long counting time. In this case true coincidence summing and self-absorption become important factors. SHAMAN is able to take into account these complicated phenomena, and the results it produces have been found to be very reliable and accurate. (author)

  12. [Development of an index system for the comprehensive evaluation on public health emergency events surveillance system in China].

    Science.gov (United States)

    Hong, Zhiheng; Ni, Daxin; Cao, Yang; Meng, Ling; Tu, Wenxiao; Li, Leilei; Li, Qun; Jin, Lianmei

    2015-06-01

    To establish a comprehensive evaluation index system for the China Public Health Emergency Events Surveillance System (CPHEESS). A draft index system was built through literature review and under the consideration of the characteristics on CPHEESS. Delphi method was adapted to determine the final index system. The index system was divided into primary, secondary and tertiary levels. There were 4 primary indicators: System structure, Network platform, Surveillance implementation reports with Data analysis and utilization. There were 16 secondary and 70 tertiary indicators being set, with System structure including 14 tertiary indicators (accounted for 20.00%), 21 Network platforms (accounted for 30.00%). Twenty-four Surveillance implementation reports (accounted for 34.29%), 11 Data analysis and utilization (accounted for 15.71%). The average score of importance of each indicators was 4.29 (3.77-4.94), with an average coefficient variation as 0.14 (0.12-0.16). The mean Chronbach's α index was 0.84 (0.81-0.89). The adaptability of each related facilities indicator was specified. The primary indicators were set in accordance with the characteristics and goals of the surveillance systems. Secondary indicators provided key elements in the management and control of the system while the tertiary indicators were available and operative. The agreement rate of experts was high with good validity and reliability. This index system could be used for CPHEESS in future.

  13. Development of a Comprehensive Fouling Model for a Rotating Membrane Bioreactor System Treating Wastewater

    Directory of Open Access Journals (Sweden)

    Parneet Paul

    2015-01-01

    Full Text Available Membrane bioreactors (MBRs are now main stream wastewater treatment technologies. In recent times, novel pressure driven rotating membrane disc modules have been specially developed that induce high shear on the membrane surface, thereby reducing fouling. Previous research has produced dead-end filtration fouling model which combines all three classical mechanisms that was later used by another researcher as a starting point for a greatly refined model of a cross flow side-stream MBR that incorporated both hydrodynamics and soluble microbial products’ (SMP effects. In this study, a comprehensive fouling model was created based on this earlier work that incorporated all three classical fouling mechanisms for a rotating MBR system. It was tested and validated for best fit using appropriate data sets. The initial model fit appeared good for all simulations, although it still needs to be calibrated using further appropriate data sets.

  14. Comparative survey of comprehensiveness of literature collection between two information systems, 2

    International Nuclear Information System (INIS)

    Narui, Shigeko; Habara, Tadashi; Izawa, Michiyo; Naramoto, Miyoko; Kajiro, Tadashi

    1984-01-01

    To make clear a feature of nuclear fusion area of the INIS database in comparison with the INSPEC, a survey has been made of overlap literature included in both databases, and of unique literature included only in the INSPEC. All of the 5,774 items in the categories a50.00 and a28.50R of the INSPEC in 1980 were checked on whether each item was also included in the fusion category A14 of the INIS during four years of 1979 to 1982 or not. The ratios of literature included in the INIS were 52 % and 84 % for journal and technical report, respectively. The ratio for journal was considered in connection with differences in the scope and coverage as well as input system between the two databases. High comprehensiveness for technical report is achievable in the INIS. Comparison of language of literature included in both databases, and time lags for publication are briefly described. (author)

  15. Comprehensive and integrated district health systems strengthening: the Rwanda Population Health Implementation and Training (PHIT) Partnership.

    Science.gov (United States)

    Drobac, Peter C; Basinga, Paulin; Condo, Jeanine; Farmer, Paul E; Finnegan, Karen E; Hamon, Jessie K; Amoroso, Cheryl; Hirschhorn, Lisa R; Kakoma, Jean Baptise; Lu, Chunling; Murangwa, Yusuf; Murray, Megan; Ngabo, Fidele; Rich, Michael; Thomson, Dana; Binagwaho, Agnes

    2013-01-01

    Nationally, health in Rwanda has been improving since 2000, with considerable improvement since 2005. Despite improvements, rural areas continue to lag behind urban sectors with regard to key health outcomes. Partners In Health (PIH) has been supporting the Rwanda Ministry of Health (MOH) in two rural districts in Rwanda since 2005. Since 2009, the MOH and PIH have spearheaded a health systems strengthening (HSS) intervention in these districts as part of the Rwanda Population Health Implementation and Training (PHIT) Partnership. The partnership is guided by the belief that HSS interventions should be comprehensive, integrated, responsive to local conditions, and address health care access, cost, and quality. The PHIT Partnership represents a collaboration between the MOH and PIH, with support from the National University of Rwanda School of Public Health, the National Institute of Statistics, Harvard Medical School, and Brigham and Women's Hospital. The PHIT Partnership's health systems support aligns with the World Health Organization's six health systems building blocks. HSS activities focus across all levels of the health system - community, health center, hospital, and district leadership - to improve health care access, quality, delivery, and health outcomes. Interventions are concentrated on three main areas: targeted support for health facilities, quality improvement initiatives, and a strengthened network of community health workers. The impact of activities will be assessed using population-level outcomes data collected through oversampling of the demographic and health survey (DHS) in the intervention districts. The overall impact evaluation is complemented by an analysis of trends in facility health care utilization. A comprehensive costing project captures the total expenditures and financial inputs of the health care system to determine the cost of systems improvement. Targeted evaluations and operational research pieces focus on specific

  16. The Roots of North America's First Comprehensive Public Health Insurance System

    Directory of Open Access Journals (Sweden)

    Ostry, Aleck

    2001-06-01

    Full Text Available The Canadian province of Saskatchewan in 1944 it inherited a long tradition of "socialized" medicine in many rural regions. However, urban medicine was based on fee-for-service payment of physicians and no private health insurance. In crafting North America's first public health insurance system, the government built on the rural medical infrastructure already in place by expanding a rural salaried system of physician payment and successfully promoted a regional comprehensive insurance system piloted in a southern region of the province. However, major demographic shifts from countryside to city during the 1950s, burgeoning physician supply, increased immigration of physicians into the provinces' cities, and aggressive expansion of urban-based private insurance for physician services into rural regions, shifted the balance of medical power away from rural towards urban centers in the province. The increasing resistance, by the medical profession, to health-care reform in Saskatchewan in the 1950s must be considered within a geographic framework as rural regions of the province became the major battleground between government and insurance third party payers. While historical comparisons should not be overstated, re-visiting this struggle may be useful in the current era in which the pressure for privatization of the medical system in Canada appear to be growing.

  17. COMPREHENSIVE DIAGNOSTIC AND IMPROVEMENT TOOLS FOR HVAC-SYSTEM INSTALLATIONS IN LIGHT COMMERCIAL BUILDINGS

    Energy Technology Data Exchange (ETDEWEB)

    Abram Conant; Mark Modera; Joe Pira; John Proctor; Mike Gebbie

    2004-10-31

    Proctor Engineering Group, Ltd. (PEG) and Carrier-Aeroseal LLP performed an investigation of opportunities for improving air conditioning and heating system performance in existing light commercial buildings. Comprehensive diagnostic and improvement tools were created to address equipment performance parameters (including airflow, refrigerant charge, and economizer operation), duct-system performance (including duct leakage, zonal flows and thermal-energy delivery), and combustion appliance safety within these buildings. This investigation, sponsored by the National Energy Technology Laboratory, a division of the U.S. Department of Energy, involved collaboration between PEG and Aeroseal in order to refine three technologies previously developed for the residential market: (1) an aerosol-based duct sealing technology that allows the ducts to be sealed remotely (i.e., without removing the ceiling tiles), (2) a computer-driven diagnostic and improvement-tracking tool for residential duct installations, and (3) an integrated diagnosis verification and customer satisfaction system utilizing a combined computer/human expert system for HVAC performance. Prior to this work the aerosol-sealing technology was virtually untested in the light commercial sector--mostly because the savings potential and practicality of this or any other type of duct sealing had not been documented. Based upon the field experiences of PEG and Aeroseal, the overall product was tailored to suit the skill sets of typical HVAC-contractor personnel.

  18. Automatic Sensor-Fault Detection System for Comprehensive Structural Health Monitoring System

    National Research Council Canada - National Science Library

    Chan, Hian-Leng; Zhang, Chang; Qing, Peter X; Ooi, Teng K; Marotta, Steve A

    2005-01-01

    Structural health monitoring systems are viewed as viable means to reduce life-cycle costs, increase structural reliability, and extend the operational hours for a wide variety of composite structures...

  19. Comprehensive Care

    Science.gov (United States)

    ... Comprehensive Care Share this page Facebook Twitter Email Comprehensive Care Understand the importance of comprehensive MS care ... In this article A complex disease requires a comprehensive approach Today multiple sclerosis (MS) is not a ...

  20. Development of a Low-cost, Comprehensive Recording System for Circadian Rhythm Behavior.

    Science.gov (United States)

    Kwon, Jea; Park, Min Gu; Lee, Seung Eun; Lee, C Justin

    2018-02-01

    Circadian rhythm is defined as a 24-hour biological oscillation, which persists even without any external cues but also can be re-entrained by various environmental cues. One of the widely accepted circadian rhythm behavioral experiment is measuring the wheel-running activity (WRA) of rodents. However, the price for commercially available WRA recording system is not easily affordable for researchers due to high-cost implementation of sensors for wheel rotation. Here, we developed a cost-effective and comprehensive system for circadian rhythm recording by measuring the house-keeping activities (HKA). We have monitored animal's HKA as electrical signal by simply connecting animal housing cage with a standard analog/digital converter: input to the metal lid and ground to the metal grid floor. We show that acquired electrical signals are combined activities of eating, drinking and natural locomotor behaviors which are well-known indicators of circadian rhythm. Post-processing of measured electrical signals enabled us to draw actogram, which verifies HKA to be reliable circadian rhythm indicator. To provide easy access of HKA recording system for researchers, we have developed user-friendly MATLAB-based software, Circa Analysis. This software provides functions for easy extraction of scalable "touch activity" from raw data files by automating seven steps of post-processing and drawing actograms with highly intuitive user-interface and various options. With our cost-effective HKA circadian rhythm recording system, we have estimated the cost of our system to be less than $150 per channel. We anticipate our system will benefit many researchers who would like to study circadian rhythm.

  1. The informational practice of the users of an information system from a comprehensive perspective

    Directory of Open Access Journals (Sweden)

    Ana Luisa de Vasconcelos Terto

    2015-02-01

    Full Text Available Objective. This research is characterized as a study of users of the Sistema de Informação da Extensão da Universidade Federal de Minas Gerais (SIEX/UFMG. The general objective of the study is to investigate the information practices of users of the system, covering both the behavioral aspects of their users and the operational aspects of the system. Method. The theory is based on (i information behavior - approaching this research studies the social approach -, (ii social phenomenology - seeking to understand users informational practices - and (iii usability - to verify users perception in relation to the system. Instead of assigning reasons for the users information behavior of users, we search to understand their motivations and perceptions. Therefore, we tried to enter the universe of users by writing in-depth semi-structured interviews to collect data. Results. The research generated good comprehensive and descriptive results, bringing relevant considerations about SIEX/UFMG and extension at the University. Conclusions. The survey revealed that the use of SIEX / UFMG goes beyond its basic functions and allows us to understand the users' perception regarding the university extension.

  2. Comprehensive Transcriptome Profiling and Functional Analysis of the Frog (Bombina maxima) Immune System

    Science.gov (United States)

    Zhao, Feng; Yan, Chao; Wang, Xuan; Yang, Yang; Wang, Guangyin; Lee, Wenhui; Xiang, Yang; Zhang, Yun

    2014-01-01

    Amphibians occupy a key phylogenetic position in vertebrates and evolution of the immune system. But, the resources of its transcriptome or genome are still little now. Bombina maxima possess strong ability to survival in very harsh environment with a more mature immune system. We obtained a comprehensive transcriptome by RNA-sequencing technology. 14.3% of transcripts were identified to be skin-specific genes, most of which were not isolated from skin secretion in previous works or novel non-coding RNAs. 27.9% of transcripts were mapped into 242 predicted KEGG pathways and 6.16% of transcripts related to human disease and cancer. Of 39 448 transcripts with the coding sequence, at least 1501 transcripts (570 genes) related to the immune system process. The molecules of immune signalling pathway were almost presented, several transcripts with high expression in skin and stomach. Experiments showed that lipopolysaccharide or bacteria challenge stimulated pro-inflammatory cytokine production and activation of pro-inflammatory caspase-1. These frog's data can remarkably expand the existing genome or transcriptome resources of amphibians, especially immunity data. The entity of the data provides a valuable platform for further investigation on more detailed immune response in B. maxima and a comparative study with other amphibians. PMID:23942912

  3. Participatory System Science: Multi-Level Comprehension Through a Game-like Process

    Science.gov (United States)

    Fatland, D. R.; Kuntz, L.

    2012-12-01

    Participatory System Science: Multi-Level Comprehension Through a Game-like Process We built a time-series game that permits the player to make water management decisions concerning the Skagit River (north-central Washington state) every five years for 60 years. This work was inspired by the integrative efforts of the Skagit Climate Science Consortium and the Climate Impacts Group at the University of Washington. Our principle guiding concepts have been - Construct a reasonable system description with -- wherever possible -- Events / Consequences rendered both visually and in terms of financial impact. - Base the system description on peer reviewed publications - Emphasize both connection and absence of connection between player Actions and subsequent Consequences in the catchment basin. Player choices center around dam flow levels and steps to mitigate negative impacts of sediment transport into the lower (populated) reaches of the Skagit River and into Puget Sound (levees, new dams, estuary restoration, etcetera). With this work we hope to explore scientific results in public awareness by engaging the game Player as a problem solver.

  4. A Comprehensive System of Energy Intensity Indicators for the US: Methods, Data and Key Trends

    Energy Technology Data Exchange (ETDEWEB)

    Belzer, David B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bender, Sadie R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Cort, Katherine A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-06-29

    This report provides an update to a previously published (Rev 1) report that describes a comprehensive system of energy intensity indicators for the United States that has been developed for the Department of Energy’s Office of Energy Efficiency and Renewable Energy (EERE) over the past decade. This system of indicators is hierarchical in nature, beginning with detailed indexes of energy intensity for various sectors of the economy, which are ultimately aggregated to an overall energy intensity index for the economy as a whole. The aggregation of energy intensity indexes to higher levels in the hierarchy is performed with a version of the Log Mean Divisia index (LMDI) method. Based upon the data and methods in the system of indicators, the economy-wide energy intensity index shows a decline of about 14% in 2011 relative to a 1985 base year. Discussion of energy intensity indicators for each of the broad end-use sectors of the economy—residential, commercial, industrial, and transportation—is presented in the report. An analysis of recent changes in the efficiency of electricity generation in the U.S. is also included. A detailed appendix describes the data sources and methodology behind the energy intensity indicators for each sector.

  5. Social Work Assessment Notes: A Comprehensive Outcomes-Based Hospice Documentation System.

    Science.gov (United States)

    Hansen, Angela Gregory; Martin, Ellen; Jones, Barbara L; Pomeroy, Elizabeth C

    2015-08-01

    This article describes the development of an integrated psychosocial patient and caregiver assessment and plan of care for hospice social work documentation. A team of hospice social workers developed the Social Work Assessment Notes as a quality improvement project in collaboration with the information technology department. Using the Social Work Assessment Tool as an organizing framework, this comprehensive hospice social work documentation system is designed to integrate assessment, planning, and outcomes measurement. The system was developed to guide the assessment of patients' and caregivers' needs related to end-of-life psychosocial issues, to facilitate collaborative care plan development, and to measure patient- and family-centered outcomes. Goals established with the patient and the caregiver are documented in the plan of care and become the foundation for patient-centered, strengths-based interventions. Likert scales are used to assign numerical severity levels for identified issues and progress made toward goals and to track the outcome of social work interventions across nine psychosocial constructs. The documentation system was developed for use in an electronic health record but can be used for paper charting. Future plans include automated aggregate outcomes measurement to identify the most effective interventions and best practices in end-of-life care.

  6. A Comprehensive Systems Testing Plan for the Smart Phone Assisted Rapid Communication and Control System (SPARCCS)

    Science.gov (United States)

    2012-09-01

    process. Interface faults can disrupt the functionality of a system ( Pressman , 2010). Interface faults can include: 1. Incorrect interrupt...and software instrumentation for full effectiveness ( Pressman , 2010). In SPARCCS testing, performance testing will be at the forefront of all test...which it is designed to operate. Deployment testing tests the following ( Pressman , 2010): 1. Installation procedures 2. Installation

  7. A systemic integrative framework to describe comprehensively a swine health system, Flanders as an example.

    Science.gov (United States)

    Rojo-Gimeno, Cristina; Dewulf, Jeroen; Maes, Dominiek; Wauters, Erwin

    2018-06-01

    A well-functioning swine health system is crucial to ensure a sustainable pig production. Yet, little attention has been paid to understand it. The objective of this study was to unravel the complexity of a swine health system by using a systems-thinking approach for the case of Flanders (Northern part of Belgium). To that end, qualitative interviews were held with 33 relevant stakeholders. A hybrid thematic analysis was conducted which consisted of two phases. First, an inductive thematic analysis was conducted and second, the resulting themes were classified into the building blocks of a systemic framework. This framework combined a structural and a functional analysis that allowed to identify the key actors and their functions. Additionally, a transformational analysis was performed to evaluate how structures and the entire swine health system enable or disable functions. Findings revealed that the Flemish swine health system presents several merits such as the synchronization of policies and sector's agreements to reduce the antimicrobial use in the pig sector and the presence of a rich network of universities and research institutes that contribute to the education of health professionals. Nevertheless, several systemic failures were observed at different levels such as the lack of a good professional body representing the swine veterinarians, the tradition that veterinary advice is provided for 'free' by feed mill companies, and the shortage of reliable farm productivity data. Both latter failures may hinder swine practitioners to provide integrative advice. While few veterinarians are remunerated per hour or per visit by farmers, the most common business model used by veterinarians is largely based on the sale of medicines. Thus, veterinarians encounter often a conflict of interest when advising on preventive vaccinations and, in turn, farmers distrust their advice. On a positive note, alternatives to the traditional business model were suggested by both

  8. "Teaching Case": ComprehensiveCare and the Stalled Adoption of an Electronic Health Records System: IT Governance and Employee Succession

    Science.gov (United States)

    Gomillion, David L.

    2017-01-01

    ComprehensiveCare, a multi-specialty healthcare organization, struggles to implement Electronic Health Records. The first adoption failed outright because the customizations made the system unusable. The second attempted adoption has not officially failed yet, but the system fails to live up to the expectations. It lingers on the edge of…

  9. The comprehensive registration and information system of radiation protection regulatory authority in the Czech Republic

    International Nuclear Information System (INIS)

    Petrova, K.

    2004-01-01

    The central registration system in radiation protection is created in the Czech Republic since the 1997 year. Since that time the central registries of licensees, ionizing radiation sources (IRS) and occupational of workers doses has been developed by the State Office for Nuclear Safety (SUJB) in accordance with the demands of the new Czech legislation. The core of this complex information system is created by the Central Register of Licensees (CRL). The Central Register of Occupational Exposure (CROE) and the Central Register of Ionising Radiation Sources (CRIRS) are connected to CRL and provides with the list of workers their doses and relevant sources for each licensee. The Central Register of Approvals (CRA) issued by SUJB has been also created in 2002 and it was implemented into the system. The further register of inspections is recently under development. The whole system is operated in Oracle database. CRL registers all relevant information on the level of licensee, their workplaces and also on the level of smaller working units (labs, buildings, ..) where is necessary for more precise information about the placement of sources. The data are updated continuously. CROE collects personal and dosimetric data for all monitored workers in whole country. This register also includes the information on the personal radiation passports distributed by SUJB to external workers. CRIRS registers sealed IRS, devices with sealed IRS, generators and specification of workplaces with unsealed IRS. Users are obliged to report information on new source specified by Decree on radiation protection within one months. They shall report also all changes of registered data including the transfer of source to another user or to final disposal. CRA enables to issue automatically the licence in unified form and provides users with the different control tools of issued licences. Described comprehensive information system serves as very important and useful tool for effective regulation

  10. Software for marine ecological environment comprehensive monitoring system based on MCGS

    Science.gov (United States)

    Wang, X. H.; Ma, R.; Cao, X.; Cao, L.; Chu, D. Z.; Zhang, L.; Zhang, T. P.

    2017-08-01

    The automatic integrated monitoring software for marine ecological environment based on MCGS configuration software is designed and developed to realize real-time automatic monitoring of many marine ecological parameters. The DTU data transmission terminal performs network communication and transmits the data to the user data center in a timely manner. The software adopts the modular design and has the advantages of stable and flexible data structure, strong portability and scalability, clear interface, simple user operation and convenient maintenance. Continuous site comparison test of 6 months showed that, the relative error of the parameters monitored by the system such as temperature, salinity, turbidity, pH, dissolved oxygen was controlled within 5% with the standard method and the relative error of the nutrient parameters was within 15%. Meanwhile, the system had few maintenance times, low failure rate, stable and efficient continuous monitoring capabilities. The field application shows that the software is stable and the data communication is reliable, and it has a good application prospect in the field of marine ecological environment comprehensive monitoring.

  11. New Developments in NOAA's Comprehensive Large Array-Data Stewardship System

    Science.gov (United States)

    Ritchey, N. A.; Morris, J. S.; Carter, D. J.

    2012-12-01

    The Comprehensive Large Array-data Stewardship System (CLASS) is part of the NOAA strategic goal of Climate Adaptation and Mitigation that gives focus to the building and sustaining of key observational assets and data archives critical to maintaining the global climate record. Since 2002, CLASS has been NOAA's enterprise solution for ingesting, storing and providing access to a host of near real-time remote sensing streams such as the Polar and Geostationary Operational Environmental Satellites (POES and GOES) and the Defense Meteorological Satellite Program (DMSP). Since October, 2011 CLASS has also been the dedicated Archive Data Segment (ADS) of the Suomi National Polar-orbiting Partnership (S-NPP). As the ADS, CLASS receives raw and processed S-NPP records for archival and distribution to the broad user community. Moving beyond just remote sensing and model data, NOAA has endorsed a plan to migrate all archive holdings from NOAA's National Data Centers into CLASS while retiring various disparate legacy data storage systems residing at the National Climatic Data Center (NCDC), National Geophysical Data Center (NGDC) and the National Oceanographic Data Center (NODC). In parallel to this data migration, CLASS is evolving to a service-oriented architecture utilizing cloud technologies for dissemination in addition to clearly defined interfaces that allow better collaboration with partners. This evolution will require implementation of standard access protocols and metadata which will lead to cost effective data and information preservation.

  12. Advances in consolidated bioprocessing systems for bioethanol and butanol production from biomass: a comprehensive review

    Directory of Open Access Journals (Sweden)

    Gholamreza Salehi Jouzani

    2015-03-01

    Full Text Available Recently, lignocellulosic biomass as the most abundant renewable resource has been widely considered for bioalcohols production. However, the complex structure of lignocelluloses requires a multi-step process which is costly and time consuming. Although, several bioprocessing approaches have been developed for pretreatment, saccharification and fermentation, bioalcohols production from lignocelluloses is still limited because of the economic infeasibility of these technologies. This cost constraint could be overcome by designing and constructing robust cellulolytic and bioalcohols producing microbes and by using them in a consolidated bioprocessing (CBP system. This paper comprehensively reviews potentials, recent advances and challenges faced in CBP systems for efficient bioalcohols (ethanol and butanol production from lignocellulosic and starchy biomass. The CBP strategies include using native single strains with cellulytic and alcohol production activities, microbial co-cultures containing both cellulytic and ethanologenic microorganisms, and genetic engineering of cellulytic microorganisms to be alcohol-producing or alcohol producing microorganisms to be cellulytic. Moreover, high-throughput techniques, such as metagenomics, metatranscriptomics, next generation sequencing and synthetic biology developed to explore novel microorganisms and powerful enzymes with high activity, thermostability and pH stability are also discussed. Currently, the CBP technology is in its infant stage, and ideal microorganisms and/or conditions at industrial scale are yet to be introduced. So, it is essential to bring into attention all barriers faced and take advantage of all the experiences gained to achieve a high-yield and low-cost CBP process.

  13. Comprehensive assessment of energy systems: approach and current results of the Swiss activities

    International Nuclear Information System (INIS)

    Hirschberg, S.; Dones, R.; Kypreos, S.

    1994-01-01

    This paper provides an overview of the approaches used and results obtained to this date within the Swiss Project GaBE on ''Comprehensive Assessment of Energy Systems''. Based on the ''cradle to grave'' approach detailed environmental inventories for major fuel cycles have been generated. In comparison to earlier studies a very broad spectrum of resources and air and water pollutants has been covered. Also non-energetic resources such as land depreciation have been considered. Numerous examples of evaluations are provided in the paper, including comparisons of greenhouse gas emissions, land use, radiation and wastes, and illustrating the impact of consideration of full energy chains. In the part concerning severe accidents some evaluations based on the database established as the Paul Scherrer Institute are presented as well as the estimated contribution of hypothetical severe accidents to the external costs associated with a specific Swiss nuclear power plant. Results of applications of the large scale energy-economy model MARKAL to the Swiss energy system and greenhouse gas scenarios are described. This includes cost-optimal contributions of different technologies to reduce CO 2 emissions, and trade-offs on the national and international level. Finally, the content of other GaBE activities either being in progress or planned is provided. (orig.)

  14. An effective and comprehensive model for optimal rehabilitation of separate sanitary sewer systems.

    Science.gov (United States)

    Diogo, António Freire; Barros, Luís Tiago; Santos, Joana; Temido, Jorge Santos

    2018-01-15

    In the field of rehabilitation of separate sanitary sewer systems, a large number of technical, environmental, and economic aspects are often relevant in the decision-making process, which may be modelled as a multi-objective optimization problem. Examples are those related with the operation and assessment of networks, optimization of structural, hydraulic, sanitary, and environmental performance, rehabilitation programmes, and execution works. In particular, the cost of investment, operation and maintenance needed to reduce or eliminate Infiltration from the underground water table and Inflows of storm water surface runoff (I/I) using rehabilitation techniques or related methods can be significantly lower than the cost of transporting and treating these flows throughout the lifespan of the systems or period studied. This paper presents a comprehensive I/I cost-benefit approach for rehabilitation that explicitly considers all elements of the systems and shows how the approximation is incorporated as an objective function in a general evolutionary multi-objective optimization model. It takes into account network performance and wastewater treatment costs, average values of several input variables, and rates that can reflect the adoption of different predictable or limiting scenarios. The approach can be used as a practical and fast tool to support decision-making in sewer network rehabilitation in any phase of a project. The fundamental aspects, modelling, implementation details and preliminary results of a two-objective optimization rehabilitation model using a genetic algorithm, with a second objective function related to the structural condition of the network and the service failure risk, are presented. The basic approach is applied to three real world cases studies of sanitary sewerage systems in Coimbra and the results show the simplicity, suitability, effectiveness, and usefulness of the approximation implemented and of the objective function proposed

  15. The Integrated Waste Tracking Systems (IWTS) - A Comprehensive Waste Management Tool

    International Nuclear Information System (INIS)

    Robert S. Anderson

    2005-01-01

    The US Department of Energy (DOE) Idaho National Laboratory (INL) site located near Idaho Falls, ID USA, has developed a comprehensive waste management and tracking tool that integrates multiple operational activities with characterization data from waste declaration through final waste disposition. The Integrated Waste Tracking System (IWTS) provides information necessary to help facility personnel properly manage their waste and demonstrate a wide range of legal and regulatory compliance. As a client?server database system, the IWTS is a proven tracking, characterization, compliance, and reporting tool that meets the needs of both operations and management while providing a high level of flexibility. This paper describes some of the history involved with the development and current use of IWTS as a comprehensive waste management tool as well as a discussion of IWTS deployments performed by the INL for outside clients. Waste management spans a wide range of activities including: work group interactions, regulatory compliance management, reporting, procedure management, and similar activities. The IWTS documents these activities and performs tasks in a computer-automated environment. Waste characterization data, container characterization data, shipments, waste processing, disposals, reporting, and limit compliance checks are just a few of the items that IWTS documents and performs to help waste management personnel perform their jobs. Throughout most hazardous and radioactive waste generating, storage and disposal sites, waste management is performed by many different groups of people in many facilities. Several organizations administer their areas of waste management using their own procedures and documentation independent of other organizations. Files are kept, some of which are treated as quality records, others not as stringent. Quality records maintain a history of: changes performed after approval, the reason for the change(s), and a record of whom and when

  16. The Integrated Waste Tracking Systems (IWTS) - A Comprehensive Waste Management Tool

    Energy Technology Data Exchange (ETDEWEB)

    Robert S. Anderson

    2005-09-01

    The US Department of Energy (DOE) Idaho National Laboratory (INL) site located near Idaho Falls, ID USA, has developed a comprehensive waste management and tracking tool that integrates multiple operational activities with characterization data from waste declaration through final waste disposition. The Integrated Waste Tracking System (IWTS) provides information necessary to help facility personnel properly manage their waste and demonstrate a wide range of legal and regulatory compliance. As a client?server database system, the IWTS is a proven tracking, characterization, compliance, and reporting tool that meets the needs of both operations and management while providing a high level of flexibility. This paper describes some of the history involved with the development and current use of IWTS as a comprehensive waste management tool as well as a discussion of IWTS deployments performed by the INL for outside clients. Waste management spans a wide range of activities including: work group interactions, regulatory compliance management, reporting, procedure management, and similar activities. The IWTS documents these activities and performs tasks in a computer-automated environment. Waste characterization data, container characterization data, shipments, waste processing, disposals, reporting, and limit compliance checks are just a few of the items that IWTS documents and performs to help waste management personnel perform their jobs. Throughout most hazardous and radioactive waste generating, storage and disposal sites, waste management is performed by many different groups of people in many facilities. Several organizations administer their areas of waste management using their own procedures and documentation independent of other organizations. Files are kept, some of which are treated as quality records, others not as stringent. Quality records maintain a history of: changes performed after approval, the reason for the change(s), and a record of whom and when

  17. [A Comprehensive Care System for Children with Anorexia Nervosa in Pediatric Practice].

    Science.gov (United States)

    Watanabe, Hisako

    2015-01-01

    Against the backdrop of rapid industrialization and westernization after the World War II, there has been an ever increasing number of children with anorexia nervosa (AN) in pediatric practice, making it one of the most common diseases in children. With a severe lack of AN specialists in Japan, pediatricians need to face the daunting task of treating AN on their own. Malnutrition overlooked during periods of growth and development yields a risk of death, growth disturbance and an intractable conditions with secondary disorders of brain atrophy, osteoporosis, infertility, maltreatment and childrearing failures, mental disorders and others, which can last for life. Prevention is the best and a must for AN, and an early detection and treatment need to be in place to mitigate its progress and aggravation. It is crucial that an effective care is provided in early, treatable stage to assist the patient back to a healthy developmental trajectory. In 1993, the Department of Pediatrics, School of Medicine, Keio University (hereafter PKU) appointed a child psychiatrist as its fulltime staff and has included inpatient treatment of AN as a compulsory item of its postgraduate training program. Over the past twenty years, PKU has developed a comprehensive treatment system of AN (Scientific Report of Ministry of Welfare and Labor 2006). In the primary care of AN, a screening tool using simple physical measurement of weight on growth chart combined with pulse proves effective. When a weight on growth chart reveals an unhealthy weight loss and is combined with bradycardia, it detects AN at sensitivity of 83% and specificity of 93%. In the secondary care of AN, 40 pediatric institutions affiliated with PKU implemented early treatment of AN with the support of the Mental Health Division of PKU. In the tertiary care for severely emaciated AN patients, an around-the-clock intensive treatment program, called Anorexia Nervosa Intensive Care Unit (ANICU) was instituted. The gist of ANICU

  18. Towards a comprehensive system of methodological considerations for cities' climate targets

    International Nuclear Information System (INIS)

    Kramers, Anna; Wangel, Josefin; Johansson, Stefan; Höjer, Mattias; Finnveden, Göran; Brandt, Nils

    2013-01-01

    Climate targets for cities abound. However, what these targets really imply is dependent on a number of decisions regarding system boundaries and methods of calculation. In order to understand and compare cities' climate targets, there is a need for a generic and comprehensive framework of key methodological considerations. This paper identifies eight key methodological considerations for the different choices that can be made when setting targets for GHG emissions in a city and arranges them in four categories: temporal scope of target, object for target setting, unit of target, and range of target. To explore how target setting is carried out in practice, the climate targets of eight European cities were analysed. The results showed that these targets cover only a limited part of what could be included. Moreover, the cities showed quite limited awareness of what is, or could be, include in the targets. This makes comparison and benchmarking between cities difficult. - Highlights: • Cities' climate targets are almost impossible to compare and benchmark. • There is a need for consistent protocols and frameworks supporting target setting. • A framework with key methodological considerations for cities' climate targets is identified. • The framework is used to explore the climate targets for eight European cities. • The difference between production- and consumption based accounting is illustrated in a new way

  19. Design and practice of a comprehensively functional integrated management information system for major construction

    Science.gov (United States)

    Liu, Yuling; Wang, Xiaoping; Zhu, Yuhui; Fei, Lanlan

    2017-08-01

    This paper introduces a Comprehensively Functional Integrated Management Information System designed for the Optical Engineering Major by the College of Optical Science and Engineering, Zhejiang University, which combines the functions of teaching, students learning, educational assessment and management. The system consists of 5 modules, major overview, online curriculum, experiment teaching management, graduation project management and teaching quality feedback. The major overview module introduces the development history, training program, curriculums and experiment syllabus and teaching achievements of optical engineering major in Zhejiang University. The Management Information System is convenient for students to learn in a mobile and personalized way. The online curriculum module makes it very easy for teachers to setup a website for new curriculums. On the website, teachers can help students on their problems about the curriculums in time and collect their homework online. The experiment teaching management module and the graduation project management module enables the students to fulfill their experiment process and graduation thesis under the help of their supervisors. Before students take an experiment in the lab, they must pass the pre-experiment quiz on the corresponding module. After the experiment, students need to submit the experiment report to the web server. Moreover, the module contains experiment process video recordings, which are very helpful to improve the effect of the experiment education. The management of the entire process of a student's graduation program, including the project selection, mid-term inspection, progress report of every two weeks, final thesis, et al, is completed by the graduation project management module. The teaching quality feedback module is not only helpful for teachers to know whether the education effect of curriculum is good or not, but also helpful for the administrators of the college to know whether the

  20. The influence of age, hearing, and working memory on the speech comprehension benefit derived from an automatic speech recognition system

    NARCIS (Netherlands)

    Zekveld, A.A.; Kramer, S.E.; Kessens, J.M.; Vlaming, M.S.M.G.; Houtgast, T.

    2009-01-01

    Objective: The aim of the current study was to examine whether partly incorrect subtitles that are automatically generated by an Automatic Speech Recognition (ASR) system, improve speech comprehension by listeners with hearing impairment. In an earlier study (Zekveld et al. 2008), we showed that

  1. Measuring Listening Comprehension Skills of 5th Grade School Students with the Help of Web Based System

    Science.gov (United States)

    Acat, M. Bahaddin; Demiral, Hilmi; Kaya, Mehmet Fatih

    2016-01-01

    The main purpose of this study is to measure listening comprehension skills of 5th grade school students with the help of web based system. This study was conducted on 5th grade students studying at the primary schools of Eskisehir. The scale used in the process of the study is "Web Based Listening Scale". In the process of the study,…

  2. Test Review: Naglieri, J. A., Goldstein, S. (2013), "Comprehensive Executive Function Inventory." North Tonawanda, NY: Multi-Health Systems

    Science.gov (United States)

    Fenwick, Melanie; McCrimmon, Adam W.

    2015-01-01

    This article provides a description and review of the "Comprehensive Executive Function Inventory" (CEFI; Naglieri & Goldstein, 2013), published by Multi-Health Systems Inc. (MHS). It is a rating scale developed to measure a wide array of Executive Function (EF) abilities in individuals aged 5 through 18 years. Completed by a parent,…

  3. Toward a sustainable waste management system: a comprehensive assessment of thermal and electric energy recovery from waste incineration

    Energy Technology Data Exchange (ETDEWEB)

    Salvia, Monica; Cosmi, Carmelina; Cuomo, Vincenzo; Macchiato, Maria [Istituto Nazionale per la Fisica della Materia, Napoli (Italy); Mangiamele, Lucia [Univ. della Basilicata, Potenza (Italy). Dipt. Ingegneria e Fisica dell Ambiente; Pietrapertosa, Filomena [Univ. di Napoli Federico II, (Italy). Dipt. di Scienze Fisiche

    2002-12-01

    Energy-environmental planning must join normative, environmental and socio-economic features to obtain effective strategies aimed to a sustainable development. Therefore a comprehensive methodology for the analysis and the optimisation of the anthropogenic activities system configuration, can usefully support decision-makers in the definition of harmonised sector plans, joining waste management issues with resource use problems and exploiting energy and materials feedback among supply and demand sectors. In this paper we present an innovative application of the Advanced Local Energy Environmental Planning methodology (ALEP), aimed to the definition of optimal waste management strategies which comply with comprehensive as well as sectorial issues.

  4. The influence of age, hearing, and working memory on the speech comprehension benefit derived from an automatic speech recognition system.

    Science.gov (United States)

    Zekveld, Adriana A; Kramer, Sophia E; Kessens, Judith M; Vlaming, Marcel S M G; Houtgast, Tammo

    2009-04-01

    The aim of the current study was to examine whether partly incorrect subtitles that are automatically generated by an Automatic Speech Recognition (ASR) system, improve speech comprehension by listeners with hearing impairment. In an earlier study (Zekveld et al. 2008), we showed that speech comprehension in noise by young listeners with normal hearing improves when presenting partly incorrect, automatically generated subtitles. The current study focused on the effects of age, hearing loss, visual working memory capacity, and linguistic skills on the benefit obtained from automatically generated subtitles during listening to speech in noise. In order to investigate the effects of age and hearing loss, three groups of participants were included: 22 young persons with normal hearing (YNH, mean age = 21 years), 22 middle-aged adults with normal hearing (MA-NH, mean age = 55 years) and 30 middle-aged adults with hearing impairment (MA-HI, mean age = 57 years). The benefit from automatic subtitling was measured by Speech Reception Threshold (SRT) tests (Plomp & Mimpen, 1979). Both unimodal auditory and bimodal audiovisual SRT tests were performed. In the audiovisual tests, the subtitles were presented simultaneously with the speech, whereas in the auditory test, only speech was presented. The difference between the auditory and audiovisual SRT was defined as the audiovisual benefit. Participants additionally rated the listening effort. We examined the influences of ASR accuracy level and text delay on the audiovisual benefit and the listening effort using a repeated measures General Linear Model analysis. In a correlation analysis, we evaluated the relationships between age, auditory SRT, visual working memory capacity and the audiovisual benefit and listening effort. The automatically generated subtitles improved speech comprehension in noise for all ASR accuracies and delays covered by the current study. Higher ASR accuracy levels resulted in more benefit obtained

  5. The Photo-3 model: A Python-based model for C3, C4, and CAM photosynthesis coupled with environmental conditions

    Science.gov (United States)

    Hartzell, S. R.; Bartlett, M. S., Jr.; Porporato, A. M.

    2017-12-01

    The ability to depict all three photosynthetic types (C3, C4, and CAM) has important implications for the study of both natural and agroecosystems. Currently no model exists which covers all types of photosynthesis in a consistent way and which can be fully integrated with environmental conditions. This is partially because, despite the fact that Crassulacean acid metabolism (CAM) photosynthesis is prevalent in many plants in arid and semi-arid ecosystems, where it may comprise nearly 50% of all plant biomass, CAM modelling remains understudied. The Photo-3 model takes advantage of recent advances in mechanistic modeling of CAM photosynthesis to provide a direct comparison of CAM functioning with C3 and C4 functioning under a wide range of soil and atmospheric conditions. The model is based on a core Farquhar photosynthetic model with additional functions to represent the spatial and temporal separations of carbon uptake and assimilation in the case of C4 and CAM photosynthesis. We have parameterized the model for one representative species of each photosynthetic type: Opuntia ficus-indica (CAM), Sorghum bicolor (C4), and Triticum aestivum (C3). Results agree well with experimental data on carbon assimilation and water use for the three species. Model runs using climate data from Temple, TX; Sicily, Italy; Zacatecas, Mexico; Pernambuco, Brazil and Adias Ababa, Ethiopia illustrate the high water use efficiency of CAM plants and its cumulative effects on long-term productivity in water-limited environments. The Photo-3 model, which is written in Python, will be made publicly available on GitHub and its outputs may be coupled to existing models of plant growth and phenology. The model may be used to evaluate potential productivity and water use for C3, C4, and CAM plants, and to devise optimal strategies for cropping systems and irrigation in water-limited environments.

  6. Comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes

    Directory of Open Access Journals (Sweden)

    Makarova Kira S

    2009-06-01

    Full Text Available Abstract Background The prokaryotic toxin-antitoxin systems (TAS, also referred to as TA loci are widespread, mobile two-gene modules that can be viewed as selfish genetic elements because they evolved mechanisms to become addictive for replicons and cells in which they reside, but also possess "normal" cellular functions in various forms of stress response and management of prokaryotic population. Several distinct TAS of type 1, where the toxin is a protein and the antitoxin is an antisense RNA, and numerous, unrelated TAS of type 2, in which both the toxin and the antitoxin are proteins, have been experimentally characterized, and it is suspected that many more remain to be identified. Results We report a comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems in prokaryotes. Using sensitive methods for distant sequence similarity search, genome context analysis and a new approach for the identification of mobile two-component systems, we identified numerous, previously unnoticed protein families that are homologous to toxins and antitoxins of known type 2 TAS. In addition, we predict 12 new families of toxins and 13 families of antitoxins, and also, predict a TAS or TAS-like activity for several gene modules that were not previously suspected to function in that capacity. In particular, we present indications that the two-gene module that encodes a minimal nucleotidyl transferase and the accompanying HEPN protein, and is extremely abundant in many archaea and bacteria, especially, thermophiles might comprise a novel TAS. We present a survey of previously known and newly predicted TAS in 750 complete genomes of archaea and bacteria, quantitatively demonstrate the exceptional mobility of the TAS, and explore the network of toxin-antitoxin pairings that combines plasticity with selectivity. Conclusion The defining properties of the TAS, namely, the typically small size of the toxin and antitoxin genes, fast evolution, and

  7. Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes.

    Science.gov (United States)

    Makarova, Kira S; Wolf, Yuri I; Koonin, Eugene V

    2009-06-03

    The prokaryotic toxin-antitoxin systems (TAS, also referred to as TA loci) are widespread, mobile two-gene modules that can be viewed as selfish genetic elements because they evolved mechanisms to become addictive for replicons and cells in which they reside, but also possess "normal" cellular functions in various forms of stress response and management of prokaryotic population. Several distinct TAS of type 1, where the toxin is a protein and the antitoxin is an antisense RNA, and numerous, unrelated TAS of type 2, in which both the toxin and the antitoxin are proteins, have been experimentally characterized, and it is suspected that many more remain to be identified. We report a comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems in prokaryotes. Using sensitive methods for distant sequence similarity search, genome context analysis and a new approach for the identification of mobile two-component systems, we identified numerous, previously unnoticed protein families that are homologous to toxins and antitoxins of known type 2 TAS. In addition, we predict 12 new families of toxins and 13 families of antitoxins, and also, predict a TAS or TAS-like activity for several gene modules that were not previously suspected to function in that capacity. In particular, we present indications that the two-gene module that encodes a minimal nucleotidyl transferase and the accompanying HEPN protein, and is extremely abundant in many archaea and bacteria, especially, thermophiles might comprise a novel TAS. We present a survey of previously known and newly predicted TAS in 750 complete genomes of archaea and bacteria, quantitatively demonstrate the exceptional mobility of the TAS, and explore the network of toxin-antitoxin pairings that combines plasticity with selectivity. The defining properties of the TAS, namely, the typically small size of the toxin and antitoxin genes, fast evolution, and extensive horizontal mobility, make the task of

  8. Who Has a Good Relationship with the Teachers? A Comparison of Comprehensive Education Systems with Education Systems Using Between-School Tracking

    Science.gov (United States)

    Vieluf, Svenja; Hochweber, Jan; Klieme, Eckhard; Kunter, Mareike

    2015-01-01

    In the present study we compared comprehensive education systems and education systems using between-school tracking with regard to disparities in the quality of student-teacher relations between low and high achieving students, between students with different socioeconomic backgrounds, and between schools with different achievement and social…

  9. SSD for R: A Comprehensive Statistical Package to Analyze Single-System Data

    Science.gov (United States)

    Auerbach, Charles; Schudrich, Wendy Zeitlin

    2013-01-01

    The need for statistical analysis in single-subject designs presents a challenge, as analytical methods that are applied to group comparison studies are often not appropriate in single-subject research. "SSD for R" is a robust set of statistical functions with wide applicability to single-subject research. It is a comprehensive package…

  10. Comprehensive assessment of regional selenium resources in soils based on the analytic hierarchy process: Assessment system construction and case demonstration.

    Science.gov (United States)

    Liang, Ruoyu; Song, Shuai; Shi, Yajing; Shi, Yajuan; Lu, Yonglong; Zheng, Xiaoqi; Xu, Xiangbo; Wang, Yurong; Han, Xuesong

    2017-12-15

    The redundancy or deficiency of selenium in soils can cause adverse effects on crops and even threaten human health. It was necessary to assess selenium resources with a rigorous scientific appraisal. Previous studies of selenium resource assessment were usually carried out using a single index evaluation. A multi-index evaluation method (analytic hierarchy process) was used in this study to establish a comprehensive assessment system based on consideration of selenium content, soil nutrients and soil environmental quality. The criteria for the comprehensive assessment system were classified by summing critical values in the standards with weights and a Geographical Information System was used to reflect the regional distribution of the assessment results. Boshan, a representative region for developing selenium-rich agriculture, was taken as a case area and classified into Zone I-V, which suggested priority areas for developing selenium-rich agriculture. Most parts of the North and Midlands of Boshan were relatively suitable for development of selenium-rich agriculture. Soils in south fractions were contaminated by Cd, PAHs, HCHs and DDTs, in which it was forbidden to farm. This study was expected to provide the basis for developing selenium-rich agriculture and an example for comprehensive evaluation of relevant resources in a region. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Comprehensive Regional Modeling for Long-Range Planning: Linking Integrated Urban Models and Geographic Information Systems

    OpenAIRE

    Johnston, Robert; de la Barra, Thomas

    2000-01-01

    This study demonstrates the sequential linking of two types of models to permit the comprehensive evaluation of regional transportation and land use policies. First, we operate an integrated urban model (TRANUS), which represents both land and travel markets with zones and networks. The travel and land use projections from TRANUS are outlined, to demonstrate the general reasonableness of the results, as this is the first application of a market-based urban model in the US. Second, the land us...

  12. A multimedia comprehensive informatics system with decision support tools for a multi-site collaboration research of stroke rehabilitation

    Science.gov (United States)

    Wang, Ximing; Documet, Jorge; Garrison, Kathleen A.; Winstein, Carolee J.; Liu, Brent

    2012-02-01

    Stroke is a major cause of adult disability. The Interdisciplinary Comprehensive Arm Rehabilitation Evaluation (I-CARE) clinical trial aims to evaluate a therapy for arm rehabilitation after stroke. A primary outcome measure is correlative analysis between stroke lesion characteristics and standard measures of rehabilitation progress, from data collected at seven research facilities across the country. Sharing and communication of brain imaging and behavioral data is thus a challenge for collaboration. A solution is proposed as a web-based system with tools supporting imaging and informatics related data. In this system, users may upload anonymized brain images through a secure internet connection and the system will sort the imaging data for storage in a centralized database. Users may utilize an annotation tool to mark up images. In addition to imaging informatics, electronic data forms, for example, clinical data forms, are also integrated. Clinical information is processed and stored in the database to enable future data mining related development. Tele-consultation is facilitated through the development of a thin-client image viewing application. For convenience, the system supports access through desktop PC, laptops, and iPAD. Thus, clinicians may enter data directly into the system via iPAD while working with participants in the study. Overall, this comprehensive imaging informatics system enables users to collect, organize and analyze stroke cases efficiently.

  13. The concept of “Comprehensive security” as a draft for reconstructing security in a system of international relations

    Directory of Open Access Journals (Sweden)

    MSc. Dritëro Arifi

    2011-03-01

    Full Text Available To explain how applicable the concept of "comprehensive secu-rity" is in Kosovo, at first, I will try to analyze the term of security, and development of international relations in relation to the phe-nomenon of "Security". Initially the term “security” is to be elabo-rated, in theoretical terms, the impact "national security" had du-ring the Cold War, and the development of the international rela-tions system, especially after "the fall of the Berlin Wall,” and the fall of communism. In the broadest sense, the post- modern securi-ty is characterized by many threats, such as terrorism, failing sta-tes, climate change etc. The elements of comprehensive security will be part of the analysis of developments in Kosovo after the war and briefly transformation of the security sector after inde-pendence.

  14. Comprehensive Modeling and Analysis of Rotorcraft Variable Speed Propulsion System With Coupled Engine/Transmission/Rotor Dynamics

    Science.gov (United States)

    DeSmidt, Hans A.; Smith, Edward C.; Bill, Robert C.; Wang, Kon-Well

    2013-01-01

    This project develops comprehensive modeling and simulation tools for analysis of variable rotor speed helicopter propulsion system dynamics. The Comprehensive Variable-Speed Rotorcraft Propulsion Modeling (CVSRPM) tool developed in this research is used to investigate coupled rotor/engine/fuel control/gearbox/shaft/clutch/flight control system dynamic interactions for several variable rotor speed mission scenarios. In this investigation, a prototypical two-speed Dual-Clutch Transmission (DCT) is proposed and designed to achieve 50 percent rotor speed variation. The comprehensive modeling tool developed in this study is utilized to analyze the two-speed shift response of both a conventional single rotor helicopter and a tiltrotor drive system. In the tiltrotor system, both a Parallel Shift Control (PSC) strategy and a Sequential Shift Control (SSC) strategy for constant and variable forward speed mission profiles are analyzed. Under the PSC strategy, selecting clutch shift-rate results in a design tradeoff between transient engine surge margins and clutch frictional power dissipation. In the case of SSC, clutch power dissipation is drastically reduced in exchange for the necessity to disengage one engine at a time which requires a multi-DCT drive system topology. In addition to comprehensive simulations, several sections are dedicated to detailed analysis of driveline subsystem components under variable speed operation. In particular an aeroelastic simulation of a stiff in-plane rotor using nonlinear quasi-steady blade element theory was conducted to investigate variable speed rotor dynamics. It was found that 2/rev and 4/rev flap and lag vibrations were significant during resonance crossings with 4/rev lagwise loads being directly transferred into drive-system torque disturbances. To capture the clutch engagement dynamics, a nonlinear stick-slip clutch torque model is developed. Also, a transient gas-turbine engine model based on first principles mean

  15. Comprehensive transportation risk assessment system based on unit-consequence factors

    International Nuclear Information System (INIS)

    Biwer, B.M.; Monette, F.A.; LePoire, D.J.; Chen, S.Y.

    1994-01-01

    The U.S. Department of Energy (DOE) Environmental Restoration and Waste Management Programmatic Environmental Impact Statement requires a comprehensive transportation risk analysis of radioactive waste shipments for large shipping campaigns. Thousands of unique shipments involving truck and rail transport must be analyzed; a comprehensive risk analysis is impossible with currently available methods. Argonne National Laboratory developed a modular transportation model that can handle the demands imposed by such an analysis. The modular design of the model facilitates the simple addition/updating of transportation routes and waste inventories, as required, and reduces the overhead associated with file maintenance and quality assurance. The model incorporates unit-consequences factors generated with the RADTRAN 4 transportation risk analysis code that are combined with an easy-to-use, menu-driven interface on IBM-compatible computers running under DOS. User selection of multiple origin/destination site pairs for the shipment of multiple radioactive waste inventories is permitted from pop-up lists. Over 800 predefined routes are available among more than 30 DOE sites and waste inventories that include high-level waste, spent nuclear fuel, transuranic waste, low-level waste, low-level mixed waste, and greater-than-Class C waste

  16. The validity of Cloze Oriented System (COS: a correlation study with an electronic comprehension test and a reading attitude survey

    Directory of Open Access Journals (Sweden)

    Maria Cristina Rodrigues Azevedo Joly

    Full Text Available This study aimed to analyze the efficiency of the Cloze Oriented System (COS considering its relation with reading attitude and its validity. The Electronic Program Comprehension (EPC for students from K1 to K4 based on the COS parts of stories from the Brazilian Children's literature was applied in eighteen class-hours. The 40 subjects, ten in each grade, of both genders aged 7 to 11 years, were evaluated before and after the EPC with a Cloze test. They answered the Elementary Reading Attitude Survey too, in a printed protocol adapted to Portuguese, to evaluate the reading attitude of the students and the influence of the EPC in the academic and recreational reading. The results showed that the performance in reading comprehension of all the subjects was higher after taking part in the EPC, and also had significant differences in reading attitude, according to the results of the T of Wilcoxon statistic test. A correlation between comprehension performance before and after the EPC and the reading attitude was verified. There was significant difference for academic reading attitude in the post-test between proficient readers and the one's that has low skill.

  17. A comprehensive economic evaluation of integrated desalination systems, including environmental costs

    International Nuclear Information System (INIS)

    Nisan, S.

    2007-01-01

    Seawater desalination is now widely accepted as an attractive alternative source of freshwater for domestic and industrial uses. Despite the considerable progress made in the relevant technologies desalination, however, remains an energy intensive process in which the energy cost is the paramount factor. Many papers have already been published on desalination economics but a comprehensive study, based on the exhaustive analysis of a combination of energy sources and desalination processes, using state of the art economic models and realistic assumptions, is still quite rare. The aim of this paper is to fulfil this gap with a view to provide clear choices of techno-economic options to decision makers in a wide range of countries be they from the developed regions or emerging countries

  18. A comprehensive summary of the ORNL Groundwater Compliance and Surveillance Sampling Results Software System

    International Nuclear Information System (INIS)

    Loffman, R.S.

    1995-01-01

    Groundwater compliance and surveillance activities are conducted at ORNL to fulfill federal and state requirements for environmental monitoring. Information management is an important aspect of this and encompasses many activities which usually have spcific time frames and schedules. In addition to fulfilling these immediate requirements, the results for the monitoring activities are also used to determine the need for environmental remediation. ORNL performs this groundwater results data management and reporting utilizing a group of SAS reg-sign applications and tools which provide the ability to track samples, capture field measurements, verify and validate result data, manage data, and report results in a variety of ways and in a timely manner. This paper provides a comprehensive summary of these applications and tools

  19. Deepen the Teaching Reform of Operating System, Cultivate the Comprehensive Quality of Students

    Science.gov (United States)

    Liu, Jianjun

    2010-01-01

    Operating system is the core course of the specialty of computer science and technology. To understand and master the operating system will directly affect students' further study on other courses. The course of operating system focuses more on theories. Its contents are more abstract and the knowledge system is more complicated. Therefore,…

  20. Comprehensive assessment of the role and potential for solar thermal in future energy systems

    DEFF Research Database (Denmark)

    Hansen, Kenneth; Mathiesen, Brian Vad

    2018-01-01

    to the energy system configurations. Solar thermal benefits reduce when moving towards a high-renewable energy system as other renewable energy sources start competing with solar thermal on energy prices and energy system flexibility. The findings can be applied to a diversity of energy systems also beyond...

  1. Comprehensive approach to ocular consequences of Stevens Johnson Syndrome - the aftermath of a systemic condition.

    Science.gov (United States)

    Iyer, Geetha; Srinivasan, Bhaskar; Agarwal, Shweta; Kamala Muralidharan, Seema; Arumugam, Sumathi

    2014-03-01

    Stevens Johnson Syndrome (SJS) can lead to end stage corneal blindness. This study describes the comprehensive treatment measures and their outcomes in the management of ocular sequelae and complications of SJS. Four hundred sixty-four eyes of 232 patients of SJS who underwent surgical intervention (punctal cautery, mucus membrane grafting for lid margin keratinisation, fornix reconstructive procedures, tectonic procedures, keratoplasty and keratoprosthesis) were studied. It was a non-comparative, retrospective, interventional case series. The primary outcome was the change in the best corrected visual acuity (BCVA). Secondary outcome measures included an improvement in the ocular surface status as indicated by corneal epithelial fluorescein staining and Schirmer's I strip wetting. The BCVA and the ocular surface status improved and/or stabilized in > 70 % of eyes following punctal cautery (n = 160) and > 80 % of eyes following lid margin mucus membrane grafting (n = 238). BCVA improved in 50 % of eyes following fornix reconstructive procedures (n = 24) with COMET (n = 6), in 63.9 % eyes with the Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) lens (n = 36), in 81.8 % of eyes after cataract surgery (n = 22). A BCVA of ≥20/200 was achieved in 72.34 % of eyes following keratoprostheses procedures (n = 47). The mean duration of follow up was 53.3 ± 15.2 months. The ocular sequelae of Stevens Johnson Syndrome can be blinding. They need to be identified and addressed early to retard the continued deterioration of the ocular surface. Our study aims to highlight the problem as well as the importance of comprehensive measures in the management of this potentially blinding disorder.

  2. The concept of “Comprehensive security” as a draft for reconstructing security in a system of international relations

    OpenAIRE

    MSc. Dritëro Arifi

    2011-01-01

    To explain how applicable the concept of "comprehensive secu-rity" is in Kosovo, at first, I will try to analyze the term of security, and development of international relations in relation to the phe-nomenon of "Security". Initially the term “security” is to be elabo-rated, in theoretical terms, the impact "national security" had du-ring the Cold War, and the development of the international rela-tions system, especially after "the fall of the Berlin Wall,” and the fall of communism. In the ...

  3. A Comprehensive System of Energy Intensity Indicators for the U.S.: Methods, Data and Key Trends

    Energy Technology Data Exchange (ETDEWEB)

    Belzer, D. B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-08-01

    This report describes a comprehensive system of energy intensity indicators for the United States that has been developed for the Department of Energy's Office of Energy Efficiency and Renewable Energy (EERE) over the past decade. This system of indicators is hierarchical in nature, beginning with detailed indexes of energy intensity for various sectors of the economy, which are ultimately aggregated to an overall energy intensity index for the economy as a whole. The aggregation of energy intensity indexes to higher levels in the hierarchy is performed with a version of the Log Mean Divisia index (LMDI) method. Based upon the data and methods in the system of indicators, the economy-wide energy intensity index shows a decline of about 14% in 2011 relative to a 1985 base year.

  4. Technology acceptance for an Intelligent Comprehensive Interactive Care (ICIC system for care of the elderly: a survey-questionnaire study.

    Directory of Open Access Journals (Sweden)

    Alice M K Wong

    Full Text Available The key components of caring for the elderly are diet, living, transportation, education, and safety issues, and telemedical systems can offer great assistance. Through the integration of personal to community information technology platforms, we have developed a new Intelligent Comprehensive Interactive Care (ICIC system to provide comprehensive services for elderly care. The ICIC system consists of six items, including medical care (physiological measuring system, Medication Reminder, and Dr. Ubiquitous, diet, living, transportation, education (Intelligent Watch, entertainment (Sharetouch, and safety (Fall Detection. In this study, we specifically evaluated the users' intention of using the Medication Reminder, Dr. Ubiquitous, Sharetouch, and Intelligent Watch using a modified technological acceptance model (TAM. A total of 121 elderly subjects (48 males and 73 females were recruited. The modified TAM questionnaires were collected after they had used these products. For most of the ICIC units, the elderly subjects revealed great willingness and/or satisfaction in using this system. The elderly users of the Intelligent Watch showed the greatest willingness and satisfaction, while the elderly users of Dr. Ubiquitous revealed fair willingness in the dimension of perceived ease of use. The old-old age group revealed greater satisfaction in the dimension of result demonstrability for the users of the Medication Reminder as compared to the young-old and oldest-old age groups. The women revealed greater satisfaction in the dimension of perceived ease of use for the users of Dr. Ubiquitous as compared to the men. There were no statistically significant differences in terms of gender, age, and education level in the other dimensions. The modified TAM showed its effectiveness in evaluating the acceptance and characteristics of technologic products for the elderly user. The ICIC system offers a user-friendly solution in telemedical care and improves the

  5. Technology acceptance for an Intelligent Comprehensive Interactive Care (ICIC) system for care of the elderly: a survey-questionnaire study.

    Science.gov (United States)

    Wong, Alice M K; Chang, Wei-Han; Ke, Pei-Chih; Huang, Chun-Kai; Tsai, Tsai-Hsuan; Chang, Hsien-Tsung; Shieh, Wann-Yun; Chan, Hsiao-Lung; Chen, Chih-Kuang; Pei, Yu-Cheng

    2012-01-01

    The key components of caring for the elderly are diet, living, transportation, education, and safety issues, and telemedical systems can offer great assistance. Through the integration of personal to community information technology platforms, we have developed a new Intelligent Comprehensive Interactive Care (ICIC) system to provide comprehensive services for elderly care. The ICIC system consists of six items, including medical care (physiological measuring system, Medication Reminder, and Dr. Ubiquitous), diet, living, transportation, education (Intelligent Watch), entertainment (Sharetouch), and safety (Fall Detection). In this study, we specifically evaluated the users' intention of using the Medication Reminder, Dr. Ubiquitous, Sharetouch, and Intelligent Watch using a modified technological acceptance model (TAM). A total of 121 elderly subjects (48 males and 73 females) were recruited. The modified TAM questionnaires were collected after they had used these products. For most of the ICIC units, the elderly subjects revealed great willingness and/or satisfaction in using this system. The elderly users of the Intelligent Watch showed the greatest willingness and satisfaction, while the elderly users of Dr. Ubiquitous revealed fair willingness in the dimension of perceived ease of use. The old-old age group revealed greater satisfaction in the dimension of result demonstrability for the users of the Medication Reminder as compared to the young-old and oldest-old age groups. The women revealed greater satisfaction in the dimension of perceived ease of use for the users of Dr. Ubiquitous as compared to the men. There were no statistically significant differences in terms of gender, age, and education level in the other dimensions. The modified TAM showed its effectiveness in evaluating the acceptance and characteristics of technologic products for the elderly user. The ICIC system offers a user-friendly solution in telemedical care and improves the quality of

  6. Comprehensive method of common-mode failure analysis for LMFBR safety systems

    International Nuclear Information System (INIS)

    Unione, A.J.; Ritzman, R.L.; Erdmann, R.C.

    1976-01-01

    A technique is demonstrated which allows the systematic treatment of common-mode failures of safety system performance. The technique uses log analysis in the form of fault and success trees to qualitatively assess the sources of common-mode failure and quantitatively estimate the contribution to the overall risk of system failure. The analysis is applied to the secondary control rod system of an early sized LMFBR

  7. Advanced Structural Health Monitoring System for Comprehensive Real-Time Vehicle Characterization, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — In providing an innovative solution to improving information technologies and health management systems, AGNC is proposing a significant technological achievement...

  8. Energy transformation in molecular electronic systems: Comprehensive progress report, 1986--1989

    International Nuclear Information System (INIS)

    Kasha, M.

    1989-01-01

    Our research focuses on discovering the fundamental issues in proton-transfer and charge-transfer excitations in model systems, with an eye on which molecular systems will serve as the best guide to biological systems. This report addresses an intramolecular proton transfer classification system, proton-transfer potentials, proton-transfer spectroscopy of benzanilides, proton-transfer in aminosalicylates, proton-transfer in lumichrome, development of proton-transfer lasers, and triplet excitation enhancement via proton-transfer tunneling. 6 refs., 2 figs

  9. Imbalance of kallikrein-kinin system in chronic pancreatitis combined with obesity and results of its comprehensive correction

    Directory of Open Access Journals (Sweden)

    L.S. Babinets

    2017-11-01

    Full Text Available Background. Chronic pancreatitis is one of the most common diseases in general therapeutic practice. Significant role in the onset and progression of chronic pancreatitis is played by the activation of the kallikrein-kinin system (KKS, which is involved in the development of inflammation, blood coagulation and fibrinolysis, immune responses, the formation of pain, etc. Objective: to investigate the dynamics of indicators of the kallikrein-kinin system when using metadoxine in the comprehensive therapy of patients with chronic biliary pancreatitis associated with obesity. Materials and methods. 75 patients with chronic biliary pancreatitis combined with obesity were examined. They were divided into 2 groups. The first group (30 people received the standard treatment. The second group (45 people received the standard treatment and metadoxine. Results. Analyzing the results, it has been found a reliable positive dynamics of KKS indices in both groups after the treatment. However, patients in the second group showed a more significant positive dynamics of KKS parameters: the level of proteolytic activity has decreased by 9.0 %, the kallikrein — by 20.0 %, a1-proteinase inhibitor — by 7.2 %, and prekallikrein has increased by 6.4 %, a2-macroglobulin — by 10.8 %, kininase II — by 10.7 % as compared to group 1. Conclusions. The use of methadoxine in the comprehensive therapy of patients with chronic biliary pancreatitis associated with obesity contributed to a significant increase in the effectiveness of conventional treatment.

  10. Molecular phenology in plants: in natura systems biology for the comprehensive understanding of seasonal responses under natural environments.

    Science.gov (United States)

    Kudoh, Hiroshi

    2016-04-01

    Phenology refers to the study of seasonal schedules of organisms. Molecular phenology is defined here as the study of the seasonal patterns of organisms captured by molecular biology techniques. The history of molecular phenology is reviewed briefly in relation to advances in the quantification technology of gene expression. High-resolution molecular phenology (HMP) data have enabled us to study phenology with an approach of in natura systems biology. I review recent analyses of FLOWERING LOCUS C (FLC), a temperature-responsive repressor of flowering, along the six steps in the typical flow of in natura systems biology. The extensive studies of the regulation of FLC have made this example a successful case in which a comprehensive understanding of gene functions has been progressing. The FLC-mediated long-term memory of past temperatures creates time lags with other seasonal signals, such as photoperiod and short-term temperature. Major signals that control flowering time have a phase lag between them under natural conditions, and hypothetical phase lag calendars are proposed as mechanisms of season detection in plants. Transcriptomic HMP brings a novel strategy to the study of molecular phenology, because it provides a comprehensive representation of plant functions. I discuss future perspectives of molecular phenology from the standpoints of molecular biology, evolutionary biology and ecology. © 2015 The Author. New Phytologist © 2015 New Phytologist Trust.

  11. A comprehensive survey of wearable and wireless ECG monitoring systems for older adults.

    Science.gov (United States)

    Baig, Mirza Mansoor; Gholamhosseini, Hamid; Connolly, Martin J

    2013-05-01

    Wearable health monitoring is an emerging technology for continuous monitoring of vital signs including the electrocardiogram (ECG). This signal is widely adopted to diagnose and assess major health risks and chronic cardiac diseases. This paper focuses on reviewing wearable ECG monitoring systems in the form of wireless, mobile and remote technologies related to older adults. Furthermore, the efficiency, user acceptability, strategies and recommendations on improving current ECG monitoring systems with an overview of the design and modelling are presented. In this paper, over 120 ECG monitoring systems were reviewed and classified into smart wearable, wireless, mobile ECG monitoring systems with related signal processing algorithms. The results of the review suggest that most research in wearable ECG monitoring systems focus on the older adults and this technology has been adopted in aged care facilitates. Moreover, it is shown that how mobile telemedicine systems have evolved and how advances in wearable wireless textile-based systems could ensure better quality of healthcare delivery. The main drawbacks of deployed ECG monitoring systems including imposed limitations on patients, short battery life, lack of user acceptability and medical professional's feedback, and lack of security and privacy of essential data have been also discussed.

  12. A Comprehensive, Competency-Based Education Framework Using Medium-Sized ERP Systems

    Science.gov (United States)

    Scholtz, Brenda; Cilliers, Charmain; Calitz, Andre

    2012-01-01

    Graduates with industry-relevant ERP competencies are highly sought after. This requirement is due to a dominance of Enterprise Resource Planning (ERP) systems and the positive affect which good quality ERP specialists have on the success rate of ERP system implementation projects. Universities are therefore increasingly pressurised to supply…

  13. Comprehensive analysis of pipeline transportation systems for CO2 sequestration. Thermodynamics and safety problems

    International Nuclear Information System (INIS)

    Witkowski, Andrzej; Rusin, Andrzej; Majkut, Mirosław; Rulik, Sebastian; Stolecka, Katarzyna

    2013-01-01

    Highlights: • Comprehensive analysis of the efficiency and safety strategies of transport CO 2 . • Selection of safety zones around pipelines transporting CO 2 . • Optimization of CO 2 pipeline transportation conditions. - Abstract: The aim of this paper is to analyze CO 2 compression and transportation processes with safety issues for post-combustion CO 2 capture applications for basic technological concepts of a 900 MW pulverized coal-fired power plant. Four various types of compressors including a conventional multistage centrifugal compressor, an integrally geared centrifugal compressor, a supersonic shock wave compressor, and pump machines were used. This study emphasizes that total compression power is a strong function of the thermodynamic process and is not only determined by the compressor efficiency. The compressor increases the CO 2 pressure from normal pressure to critical pressure and the boosting pump continues to increase the pressure to the required pressure for the pipeline inlet. Another problem analyzed in this study is the transport of CO 2 by pipeline from the compressor outlet site to the disposal site under heat transfer conditions. Simulations were made to determine maximum safe pipeline distance to subsequent booster stations depending on inlet pressure, environmental temperature, the thermal insulation thickness and the ground level heat transfer conditions. From the point of view of environmental protection, the most important problem is to identify the hazards which indirectly affect CO 2 transportation in a strict and reliable manner. This identification is essential for effective hazard management. A failure of pipelines is usually caused by corrosion, material defects, ground movement or third party interference. After the rupture of the pipeline transporting liquid CO 2 , a large pressure drop will occur. The pressure will continue to fall until the liquid becomes a mixture of saturated vapour/liquid. In the vicinity of the

  14. Comparison and Analysis of Evaluation System of Child Care Program in Primary Health Care System in the East Azerbaijan Province Based on Comprehensive Evaluation Model (CIPP

    Directory of Open Access Journals (Sweden)

    Yalda Mousa Zadeh

    2015-08-01

    Full Text Available Background and objectives: Planning plays an important role in improving children's health and an evaluation system is necessary to planning. The purpose of this study was comparing and analyzing evaluation system of child care program in primary health care system in the Eastern Azerbaijan province based on Comprehensive Evaluation Model (CIPP. Material and Methods : This is a cross sectional study. The process includes a review of current evaluation system, comparison and analysis of the system based on a comprehensive model and to assess and identify the strengths and weaknesses of the current systems. The quantitative methods (such as brainstorming, observation and interview and consensus of study group about the results of the study were used for analyzing and interpreting results. Results: It showed that not enough attention was paid to the context and performance and the content of evaluation just includes inputs and processes based on the finding. Specific criteria and impact were considered in four areas (context, input, process and outcome and all levels which were according to the proposal and based on the CIPP model. Conclusion: Evaluation is a control process tool by higher levels and self-assessment by service provider is not considered in the current system. Evaluation includes quantitative aspects and not the quality of process. So, it is recommended that forecasting system that utilizes evaluation will result in improving future planning and a scientific model to be used in designing evaluation program. ​

  15. Comprehensive target populations for current active safety systems using national crash databases.

    Science.gov (United States)

    Kusano, Kristofer D; Gabler, Hampton C

    2014-01-01

    The objective of active safety systems is to prevent or mitigate collisions. A critical component in the design of active safety systems is the identification of the target population for a proposed system. The target population for an active safety system is that set of crashes that a proposed system could prevent or mitigate. Target crashes have scenarios in which the sensors and algorithms would likely activate. For example, the rear-end crash scenario, where the front of one vehicle contacts another vehicle traveling in the same direction and in the same lane as the striking vehicle, is one scenario for which forward collision warning (FCW) would be most effective in mitigating or preventing. This article presents a novel set of precrash scenarios based on coded variables from NHTSA's nationally representative crash databases in the United States. Using 4 databases (National Automotive Sampling System-General Estimates System [NASS-GES], NASS Crashworthiness Data System [NASS-CDS], Fatality Analysis Reporting System [FARS], and National Motor Vehicle Crash Causation Survey [NMVCCS]) the scenarios developed in this study can be used to quantify the number of police-reported crashes, seriously injured occupants, and fatalities that are applicable to proposed active safety systems. In this article, we use the precrash scenarios to identify the target populations for FCW, pedestrian crash avoidance systems (PCAS), lane departure warning (LDW), and vehicle-to-vehicle (V2V) or vehicle-to-infrastructure (V2I) systems. Crash scenarios were derived using precrash variables (critical event, accident type, precrash movement) present in all 4 data sources. This study found that these active safety systems could potentially mitigate approximately 1 in 5 of all severity and serious injury crashes in the United States and 26 percent of fatal crashes. Annually, this corresponds to 1.2 million all severity, 14,353 serious injury (MAIS 3+), and 7412 fatal crashes. In addition

  16. Response to 'Burden of proof: A comprehensive review of the feasibility of 100% renewable-electricity systems'

    DEFF Research Database (Denmark)

    Brown, Tom; Bischof-Niemz, Tobias; Breyer, Christian

    2018-01-01

    A recent article 'Burden of proof: A comprehensive review of the feasibility of 100% renewable-electricity systems' claims that many studies of 100% renewable electricity systems do not demonstrate sufficient technical feasibility, according to the criteria of the article's authors (henceforth 'the...... authors'). Here we analyse the authors' methodology and find it problematic. The feasibility criteria chosen by the authors are important, but are also easily addressed at low economic cost, while not affecting the main conclusions of the reviewed studies and certainly not affecting their technical...... feasibility. A more thorough review reveals that all of the issues have already been addressed in the engineering and modelling literature. Nuclear power, as advocated by some of the authors, faces other, genuine feasibility problems, such as the finiteness of uranium resources and a reliance on unproven...

  17. BtoxDB: a comprehensive database of protein structural data on toxin-antitoxin systems.

    Science.gov (United States)

    Barbosa, Luiz Carlos Bertucci; Garrido, Saulo Santesso; Marchetto, Reinaldo

    2015-03-01

    Toxin-antitoxin (TA) systems are diverse and abundant genetic modules in prokaryotic cells that are typically formed by two genes encoding a stable toxin and a labile antitoxin. Because TA systems are able to repress growth or kill cells and are considered to be important actors in cell persistence (multidrug resistance without genetic change), these modules are considered potential targets for alternative drug design. In this scenario, structural information for the proteins in these systems is highly valuable. In this report, we describe the development of a web-based system, named BtoxDB, that stores all protein structural data on TA systems. The BtoxDB database was implemented as a MySQL relational database using PHP scripting language. Web interfaces were developed using HTML, CSS and JavaScript. The data were collected from the PDB, UniProt and Entrez databases. These data were appropriately filtered using specialized literature and our previous knowledge about toxin-antitoxin systems. The database provides three modules ("Search", "Browse" and "Statistics") that enable searches, acquisition of contents and access to statistical data. Direct links to matching external databases are also available. The compilation of all protein structural data on TA systems in one platform is highly useful for researchers interested in this content. BtoxDB is publicly available at http://www.gurupi.uft.edu.br/btoxdb. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. The role of domain-general frontal systems in language comprehension: evidence from dual-task interference and semantic ambiguity.

    Science.gov (United States)

    Rodd, Jennifer M; Johnsrude, Ingrid S; Davis, Matthew H

    2010-12-01

    Neuroimaging studies have shown that the left inferior frontal gyrus (LIFG) plays a critical role in semantic and syntactic aspects of speech comprehension. It appears to be recruited when listeners are required to select the appropriate meaning or syntactic role for words within a sentence. However, this region is also recruited during tasks not involving sentence materials, suggesting that the systems involved in processing ambiguous words within sentences are also recruited for more domain-general tasks that involve the selection of task-relevant information. We use a novel dual-task methodology to assess whether the cognitive system(s) that are engaged in selecting word meanings are also involved in non-sentential tasks. In Experiment 1, listeners were slower to decide whether a visually presented letter is in upper or lower case when the sentence that they are simultaneously listening to contains words with multiple meanings (homophones), compared to closely matched sentences without homophones. Experiment 2 indicates that this interference effect is not tied to the occurrence of the homophone itself, but rather occurs when listeners must reinterpret a sentence that was initially misparsed. These results suggest some overlap between the cognitive system involved in semantic disambiguation and the domain-general process of response selection required for the case-judgement task. This cognitive overlap may reflect neural overlap in the networks supporting these processes, and is consistent with the proposal that domain-general selection processes in inferior frontal regions are critical for language comprehension. Copyright © 2010 Elsevier Inc. All rights reserved.

  19. Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution.

    Directory of Open Access Journals (Sweden)

    Holly R Ramage

    2009-12-01

    Full Text Available Toxin-antitoxin (TA systems, stress-responsive genetic elements ubiquitous in microbial genomes, are unusually abundant in the major human pathogen Mycobacterium tuberculosis. Why M. tuberculosis has so many TA systems and what role they play in the unique biology of the pathogen is unknown. To address these questions, we have taken a comprehensive approach to identify and functionally characterize all the TA systems encoded in the M. tuberculosis genome. Here we show that 88 putative TA system candidates are present in M. tuberculosis, considerably more than previously thought. Comparative genomic analysis revealed that the vast majority of these systems are conserved in the M. tuberculosis complex (MTBC, but largely absent from other mycobacteria, including close relatives of M. tuberculosis. We found that many of the M. tuberculosis TA systems are located within discernable genomic islands and were thus likely acquired recently via horizontal gene transfer. We discovered a novel TA system located in the core genome that is conserved across the genus, suggesting that it may fulfill a role common to all mycobacteria. By expressing each of the putative TA systems in M. smegmatis, we demonstrate that 30 encode a functional toxin and its cognate antitoxin. We show that the toxins of the largest family of TA systems, VapBC, act by inhibiting translation via mRNA cleavage. Expression profiling demonstrated that four systems are specifically activated during stresses likely encountered in vivo, including hypoxia and phagocytosis by macrophages. The expansion and maintenance of TA genes in the MTBC, coupled with the finding that a subset is transcriptionally activated by stress, suggests that TA systems are important for M. tuberculosis pathogenesis.

  20. Development of a comprehensive inventory management system for underground fiber optic conduits.

    Science.gov (United States)

    2013-03-01

    Major State Departments of Transportation operate and maintain networks of thousands of miles of conduits, many : carrying fiber optic cables that are vital to State communication systems. These conduits are located alongside or : across highways and...

  1. What is a comprehensive system of regulatory governance?; Que es un sistema Integral de Gestion Reglamentaria?

    Energy Technology Data Exchange (ETDEWEB)

    Real diaz, F. J.

    2011-07-01

    The progressive evolution and diversification of regulations concerning industrial safety has made their management increasingly complex, requiring more resources of organizations. Therefore, it is advisable that this management be made more efficient through systematization, specialization and the use of computing technologies. This is supported by the implementation of integrated regulatory management systems. This article explain the concept of integrated regulatory management systems, their structure and their advantages. It also includes a model for implementing them in an organization. (Author)

  2. The Urgent Need for a Comprehensive, Fully Integrated, Joint Intra-Theater Aeromedical Evacuation System

    Science.gov (United States)

    2017-04-06

    the Middle East and Africa , it is critical for the Army’s Medical Department (AMEDD) and the Joint Staff continue to leverage joint patient...Service and a single Service would prevent the establishment of a watered -down, lowest-common-denominator AE system that would result from a joint...to provide quality enroute care to increase survivability rates and decrease long-term morbidity. The current joint intra-theater AE system lacks

  3. Comprehensive solutions to the Bloch equations and dynamical models for open two-level systems

    Science.gov (United States)

    Skinner, Thomas E.

    2018-01-01

    The Bloch equation and its variants constitute the fundamental dynamical model for arbitrary two-level systems. Many important processes, including those in more complicated systems, can be modeled and understood through the two-level approximation. It is therefore of widespread relevance, especially as it relates to understanding dissipative processes in current cutting-edge applications of quantum mechanics. Although the Bloch equation has been the subject of considerable analysis in the 70 years since its inception, there is still, perhaps surprisingly, significant work that can be done. This paper extends the scope of previous analyses. It provides a framework for more fully understanding the dynamics of dissipative two-level systems. A solution is derived that is compact, tractable, and completely general, in contrast to previous results. Any solution of the Bloch equation depends on three roots of a cubic polynomial that are crucial to the time dependence of the system. The roots are typically only sketched out qualitatively, with no indication of their dependence on the physical parameters of the problem. Degenerate roots, which modify the solutions, have been ignored altogether. Here the roots are obtained explicitly in terms of a single real-valued root that is expressed as a simple function of the system parameters. For the conventional Bloch equation, a simple graphical representation of this root is presented that makes evident the explicit time dependence of the system for each point in the parameter space. Several intuitive, visual models of system dynamics are developed. A Euclidean coordinate system is identified in which any generalized Bloch equation is separable, i.e., the sum of commuting rotation and relaxation operators. The time evolution in this frame is simply a rotation followed by relaxation at modified rates that play a role similar to the standard longitudinal and transverse rates. These rates are functions of the applied field, which

  4. Evaluating Nonclinical Performance of the Academic Pathologist: A Comprehensive, Scalable, and Flexible System for Leadership Use.

    Science.gov (United States)

    Wiles, Austin Blackburn; Idowu, Michael O; Clevenger, Charles V; Powers, Celeste N

    2018-01-01

    Academic pathologists perform clinical duties, as well as valuable nonclinical activities. Nonclinical activities may consist of research, teaching, and administrative management among many other important tasks. While clinical duties have many clear metrics to measure productivity, like the relative value units of Medicare reimbursement, nonclinical performance is often difficult to measure. Despite the difficulty of evaluating nonclinical activities, nonclinical productivity is used to determine promotion, funding, and inform professional evaluations of performance. In order to better evaluate the important nonclinical performance of academic pathologists, we present an evaluation system for leadership use. This system uses a Microsoft Excel workbook to provide academic pathologist respondents and reviewing leadership a transparent, easy-to-complete system that is both flexible and scalable. This system provides real-time feedback to academic pathologist respondents and a clear executive summary that allows for focused guidance of the respondent. This system may be adapted to fit practices of varying size, measure performance differently based on years of experience, and can work with many different institutional values.

  5. A comprehensive study of economic unit commitment of power systems integrating various renewable generations and plug-in electric vehicles

    International Nuclear Information System (INIS)

    Yang, Zhile; Li, Kang; Niu, Qun; Xue, Yusheng

    2017-01-01

    Highlights: • A new UCsRP problem with flexible integrations is established. • A novel multi-zone sampling method is proposed for scenarios generation. • A meta-heuristic solving tool is introduced for solving the UCsRP problem. • A comprehensive study is conducted considering multiple weathers and seasons. • The economic effects of various scenarios are evaluated and compared. - Abstract: Significant penetration of renewable generations (RGs) and mass roll-out of plug-in electric vehicles (PEVs) will pay a vital role in delivering the low carbon energy future and low emissions of greenhouse gas (GHG) that are responsible for the global climate change. However, it is of considerable difficulties to precisely forecast the undispatchable and intermittent wind and solar power generations. The uncoordinated charging of PEVs imposes further challenges on the unit commitment in modern grid operations. In this paper, all these factors are comprehensively investigated for the first time within a novel hybrid unit commitment framework, namely UCsRP, which considers a wide range of scenarios in renewable generations and demand side management of dispatchable PEVs load. UCsRP is however an extremely challenging optimisation problem not only due to the large scale, mixed integer and nonlinearity, but also due to the double uncertainties relating to the renewable generations and PEV charging and discharging. In this paper, a meta-heuristic solving tool is introduced for solving the UCsRP problem. A key to improve the reliability of the unit commitment is to generate a range of scenarios based on multiple distributions of renewable generations under different prediction errors and extreme predicted value conditions. This is achieved by introducing a novel multi-zone sampling method. A comprehensive study considering four different cases of unit commitment problems with various weather and season scenarios using real power system data are conducted and solved, and smart

  6. A Comprehensive Review of the Techniques on Regenerative Shock Absorber Systems

    Directory of Open Access Journals (Sweden)

    Ran Zhang

    2018-05-01

    Full Text Available In this paper, the current technologies of the regenerative shock absorber systems have been categorized and evaluated. Three drive modes of the regenerative shock absorber systems, namely the direct drive mode, the indirect drive mode and hybrid drive mode are reviewed for their readiness to be implemented. The damping performances of the three different modes are listed and compared. Electrical circuit and control algorithms have also been evaluated to maximize the power output and to deliver the premium ride comfort and handling performance. Different types of parameterized road excitations have been applied to vehicle suspension systems to investigate the performance of the regenerative shock absorbers. The potential of incorporating nonlinearity into the regenerative shock absorber design analysis is discussed. The research gaps for the comparison of the different drive modes and the nonlinearity analysis of the regenerative shock absorbers are identified and, the corresponding research questions have been proposed for future work.

  7. CADLIVE toolbox for MATLAB: automatic dynamic modeling of biochemical networks with comprehensive system analysis.

    Science.gov (United States)

    Inoue, Kentaro; Maeda, Kazuhiro; Miyabe, Takaaki; Matsuoka, Yu; Kurata, Hiroyuki

    2014-09-01

    Mathematical modeling has become a standard technique to understand the dynamics of complex biochemical systems. To promote the modeling, we had developed the CADLIVE dynamic simulator that automatically converted a biochemical map into its associated mathematical model, simulated its dynamic behaviors and analyzed its robustness. To enhance the feasibility by CADLIVE and extend its functions, we propose the CADLIVE toolbox available for MATLAB, which implements not only the existing functions of the CADLIVE dynamic simulator, but also the latest tools including global parameter search methods with robustness analysis. The seamless, bottom-up processes consisting of biochemical network construction, automatic construction of its dynamic model, simulation, optimization, and S-system analysis greatly facilitate dynamic modeling, contributing to the research of systems biology and synthetic biology. This application can be freely downloaded from http://www.cadlive.jp/CADLIVE_MATLAB/ together with an instruction.

  8. Radiology residents' comprehension of the breast imaging reporting and data system: The ultrasound lexicon and final assessment category

    International Nuclear Information System (INIS)

    Jeong, Sun Hye; Lee, Eun Hye; Roh, Yun Ho; Kim, Min Jung; Youk, Ji Hyun; Yoon, Jung Hyun; Kim, Sung Hun; Kim, You Me

    2017-01-01

    To evaluate radiology residents' performance in interpretation and comprehension of breast ultrasonographic descriptors in the Breast Imaging Reporting and Data System (BI-RADS) to suggest the adequate duration of training in breast ultrasonography. A total of 102 radiology residents working in the Department of Radiology were included in this study. They were asked to answer 16 questions about the ultrasonographic lexicon and 11 questions about the BI-RADS category. We analyzed the proportion of correct answers according to the radiology residents’ year of training and duration of breast imaging training. With respect to the duration of breast imaging training, the proportion of correct answers for lexicon descriptors ranged from 77.2% to 81.3% (p = 0.368) and the proportion of correct answers for the BI-RADS category was highest after three-four months of training compared with after one month of training (p = 0.033). The proportion of correct answers for lexicon descriptors and BI-RADS category did not differ significantly according to the year of residency training. Radiology residents' comprehension of the BI-RADS category on breast ultrasonography was not associated with their year of residency training. Based on our findings, radiology residents' assessment of the BI-RADS category was significantly improved with three-four months of training compared with one month of training

  9. Radiology residents' comprehension of the breast imaging reporting and data system: The ultrasound lexicon and final assessment category

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Sun Hye; Lee, Eun Hye [Bucheon Hospital, Bucheon (Korea, Republic of); Roh, Yun Ho; Kim, Min Jung; Youk, Ji Hyun [Yonsei University College of Medicine, Seoul (Korea, Republic of); Yoon, Jung Hyun; Kim, Sung Hun [The Catholic University of Korea, Seoul (Korea, Republic of); Kim, You Me [Dankook University College of Medicine, Cheonan (Korea, Republic of)

    2017-07-15

    To evaluate radiology residents' performance in interpretation and comprehension of breast ultrasonographic descriptors in the Breast Imaging Reporting and Data System (BI-RADS) to suggest the adequate duration of training in breast ultrasonography. A total of 102 radiology residents working in the Department of Radiology were included in this study. They were asked to answer 16 questions about the ultrasonographic lexicon and 11 questions about the BI-RADS category. We analyzed the proportion of correct answers according to the radiology residents’ year of training and duration of breast imaging training. With respect to the duration of breast imaging training, the proportion of correct answers for lexicon descriptors ranged from 77.2% to 81.3% (p = 0.368) and the proportion of correct answers for the BI-RADS category was highest after three-four months of training compared with after one month of training (p = 0.033). The proportion of correct answers for lexicon descriptors and BI-RADS category did not differ significantly according to the year of residency training. Radiology residents' comprehension of the BI-RADS category on breast ultrasonography was not associated with their year of residency training. Based on our findings, radiology residents' assessment of the BI-RADS category was significantly improved with three-four months of training compared with one month of training.

  10. The informational practice of the users of an information system from a comprehensive perspective

    OpenAIRE

    Ana Luisa de Vasconcelos Terto; Adriana Bogliolo Sirihal Duarte

    2015-01-01

    Objective. This research is characterized as a study of users of the Sistema de Informação da Extensão da Universidade Federal de Minas Gerais (SIEX/UFMG). The general objective of the study is to investigate the information practices of users of the system, covering both the behavioral aspects of their users and the operational aspects of the system. Method. The theory is based on (i) information behavior - approaching this research studies the social approach -, (ii) social phenomenology - ...

  11. A Comprehensive Study on Technologies of Tyre Monitoring Systems and Possible Energy Solutions

    Directory of Open Access Journals (Sweden)

    Ali E. Kubba

    2014-06-01

    Full Text Available This article presents an overview on the state of the art of Tyre Pressure Monitoring System related technologies. This includes examining the latest pressure sensing methods and comparing different types of pressure transducers, particularly their power consumption and measuring range. Having the aim of this research to investigate possible means to obtain a tyre condition monitoring system (TCMS powered by energy harvesting, various approaches of energy harvesting techniques were evaluated to determine which approach is the most applicable for generating energy within the pneumatic tyre domain and under rolling tyre dynamic conditions. This article starts with an historical review of pneumatic tyre development and demonstrates the reasons and explains the need for using a tyre condition monitoring system. Following this, different tyre pressure measurement approaches are compared in order to determine what type of pressure sensor is best to consider in the research proposal plan. Then possible energy harvesting means inside land vehicle pneumatic tyres are reviewed. Following this, state of the art battery-less tyre pressure monitoring systems developed by individual researchers or by world leading tyre manufacturers are presented. Finally conclusions are drawn based on the reviewed documents cited in this article and a research proposal plan is presented.

  12. Comprehension of Competing Argument Marking Systems in Two Australian Mixed Languages

    Science.gov (United States)

    O'Shannessy, Carmel; Meakins, Felicity

    2012-01-01

    Crosslinguistic influence has been seen in bilingual adult and child learners when compared to monolingual learners. For speakers of Light Warlpiri and Gurindji Kriol there is no monolingual group for comparison, yet crosslinguistic influence can be seen in how the speakers resolve competition between case-marking and word order systems in each…

  13. The Role of Domain and System Knowledge on Text Comprehension and Information Search in Hypermedia

    Science.gov (United States)

    Waniek, Jacqueline; Schafer, Thomas

    2009-01-01

    The goal of this study was to examine the role of domain and system knowledge on learner performance in reading and information search in hypermedia. Previous studies have shown that prior knowledge is an important individual factor for effective hypermedia use. However, current research lacks a full understanding of how these two aspects of prior…

  14. [P.A.I.S., a personal medical information system. A comprehensive medical knowledge base].

    Science.gov (United States)

    Münch, E

    1994-06-01

    The electronic medical knowledge data base DOPIS is a compliation of knowledge from various special fields of medicine. Using uniform nomenclature, the data are presented on demand as they would be in a book chapter. Concise updates can be performed at low cost. The primary structure of the concept is the division of medical knowledge into data banks on diagnosis, literature, medication and pharmacology, as well as so-called electronic textbooks. All data banks and electronic textbooks are connected associatively. Visual information is obtained via the image data bank connected to the diagnosis data bank and the electronic books. Moreover, DOPIS has an integrated patient findings system, as well as an image processing and archiving system with research values enabling research functions. The diagnosis and literature data banks can be modified by the user or author, or fed with their own data (a so-called Expert System Shell). For authors from special fields working on the project, an extra Medical Electronic Publishing System has been developed and made available for the electronic textbooks. The model for the knowledge data base has been developed in the field of ENT, the programme implemented and initially ENT data have been stored.

  15. Information-analytical system for a comprehensive assessment and analysis of the enterprises

    Directory of Open Access Journals (Sweden)

    Baydybekova Saltanat Kenzhebaevna

    2015-04-01

    Lack of theoretical elaboration and high practical significance the problem of forming the system of internal control and analysis of economic organizations, the need for further development of his theory, methodology and organization, as well as great practical relevance in specific methods and techniques for its implementation led to the choice of research topic and its relevance.

  16. Model-based optimization biofilm based systems performing autotrophic nitrogen removal using the comprehensive NDHA model

    DEFF Research Database (Denmark)

    Valverde Pérez, Borja; Ma, Yunjie; Morset, Martin

    Completely autotrophic nitrogen removal (CANR) can be obtained in single stage biofilm-based bioreactors. However, their environmental footprint is compromised due to elevated N2O emissions. We developed novel spatially explicit biochemical process model of biofilm based CANR systems that predicts...

  17. Comprehensive association analysis of 27 genes from the GABAergic system in Japanese individuals affected with schizophrenia.

    Science.gov (United States)

    Balan, Shabeesh; Yamada, Kazuo; Iwayama, Yoshimi; Hashimoto, Takanori; Toyota, Tomoko; Shimamoto, Chie; Maekawa, Motoko; Takagai, Shu; Wakuda, Tomoyasu; Kameno, Yosuke; Kurita, Daisuke; Yamada, Kohei; Kikuchi, Mitsuru; Hashimoto, Tasuku; Kanahara, Nobuhisa; Yoshikawa, Takeo

    2017-07-01

    Involvement of the gamma-aminobutyric acid (GABA)-ergic system in schizophrenia pathogenesis through disrupted neurodevelopment has been highlighted in numerous studies. However, the function of common genetic variants of this system in determining schizophrenia risk is unknown. We therefore tested the association of 375 tagged SNPs in genes derived from the GABAergic system, such as GABA A receptor subunit genes, and GABA related genes (glutamate decarboxylase genes, GABAergic-marker gene, genes involved in GABA receptor trafficking and scaffolding) in Japanese schizophrenia case-control samples (n=2926; 1415 cases and 1511 controls). We observed nominal association of SNPs in nine GABA A receptor subunit genes and the GPHN gene with schizophrenia, although none survived correction for study-wide multiple testing. Two SNPs located in the GABRA1 gene, rs4263535 (P allele =0.002; uncorrected) and rs1157122 (P allele =0.006; uncorrected) showed top hits, followed by rs723432 (P allele =0.007; uncorrected) in the GPHN gene. All three were significantly associated with schizophrenia and survived gene-wide multiple testing. Haplotypes containing associated variants in GABRA1 but not GPHN were significantly associated with schizophrenia. To conclude, we provided substantiating genetic evidence for the involvement of the GABAergic system in schizophrenia susceptibility. These results warrant further investigations to replicate the association of GABRA1 and GPHN with schizophrenia and to discern the precise mechanisms of disease pathophysiology. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Comprehensive thermodynamic analysis of a renewable energy sourced hybrid heating system combined with latent heat storage

    International Nuclear Information System (INIS)

    Utlu, Zafer; Aydın, Devrim; Kıncay, Olcay

    2014-01-01

    Highlights: • An experimental thermal investigation of hybrid renewable heating system is presented. • Analyses were done by using real data obtained from a prototype structure. • Exergy efficiency of system components investigated during discharging period are close to each other as 32%. • The average input energy and exergy rates to the LHS were 0.770 and 0.027 kW. • Overall total energy and exergy efficiencies of LHS calculated as 72% and 28.4%. - Abstract: In this study an experimental thermal investigation of hybrid renewable heating system is presented. Latent heat storage stores energy, gained by solar collectors and supplies medium temperature heat to heat pump both day time also night time while solar energy is unavailable. In addition to this an accumulation tank exists in the system as sensible heat storage. It provides supply–demand balance with storing excess high temperature heat. Analyses were done according to thermodynamic’s first and second laws by using real data obtained from a prototype structure, built as part of a project. Results show that high percent of heat loses took place in heat pump with 1.83 kW where accumulator-wall heating cycle followed it with 0.42 kW. Contrarily highest break-down of exergy loses occur accumulator-wall heating cycle with 0.28 kW. Averagely 2.42 kW exergy destruction took place in whole system during the experiment. Solar collectors and heat pump are the promising components in terms of exergy destruction with 1.15 kW and 1.09 kW respectively. Exergy efficiency of system components, investigated during discharging period are in a close approximately of 32%. However, efficiency of solar collectors and charging of latent heat storage are 2.3% and 7% which are relatively low. Average overall total energy and exergy efficiencies of latent heat storage calculated as 72% and 28.4% respectively. Discharging energy efficiency of latent heat storage is the highest through all system components. Also heat

  19. A Comprehensive Evaluation of Joint Range and Angle Estimation in Indoor Ultrawideband Location Systems

    Directory of Open Access Journals (Sweden)

    Gentile Camillo

    2008-01-01

    Full Text Available Abstract Fine time resolution enables ultrawideband (UWB ranging systems to extract the first multipath arrival corresponding to the range between a transmitter and receiver, even when attenuated in strength compared to later arrivals. Bearing systems alone lack any notion of time and in general select the strongest arrival which is rarely the first one in nonline-of-sight conditions. Complementing UWB ranging systems with bearing capabilities allows indexing the arrivals as a function of both time and angle in order to isolate the first, providing precision range and angle. However, that precision degrades with the increasing presence of walls and other objects which distort the properties of the first arrival. In order to gauge the physical limits of the joint UWB system, we design and assemble a spatial-temporal channel sounder using a vector network analyzer coupled to a virtual antenna array, and conduct 200 experiments to measure the time- and angle-of-flight. The experiments are carried out in both line-of-sight and nonline-of-sight conditions up to an unprecedented 45 meters throughout four separate buildings with dominant wall material varying from sheet rock to steel. In addition, we report performance for varying bandwidth and center frequency of the system. We find that operating at a bandwidth of 4 GHz suffices in resolving multipath in most buildings and in excess shows virtually no improvement. While the range error decreases at lower center frequencies, the higher frequencies offer better angular resolution and so smaller angle error.

  20. Development of comprehensive HFE guidelines for the evaluation of NPP human systems interfaces

    International Nuclear Information System (INIS)

    O'Hara, J.M.; Brown, W.S.; Wachtel, J.

    1994-01-01

    Advanced control room (ACR) concepts are being developed in the commercial nuclear power industry as part of future reactor designs. The ACRs will use advanced human-system interface (HSI) technologies that may have significant implications for plant safety in that they will affect the ways in which the operator interacts with and supervises an increasingly complex system. The US Nuclear Regulatory Commission (NRC) reviews the HSI aspects of control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported to protect public health and safety. The NRC is developing guidelines to support its review of these advanced designs. This paper discusses (1) the development of guidelines for advanced HSI review, (2) the integration of those guidelines with existing guidance, and (3) a methodology for further guidance development

  1. NJOY. A comprehensive system for the processing of ENDF formatted nuclear data

    International Nuclear Information System (INIS)

    Muir, D.W.

    1990-07-01

    An introduction to the program system NJOY is given which processes data files of evaluated neutron nuclear data coded in ENDF format. NJOY is primarily used for neutron and photon transport calculations for nuclear power reactor design. The NJOY code is not available from the IAEA Nuclear Data Section but may be obtained from the Reactor Shielding Information Center, Oak Ridge, USA. (author). 10 refs, 1 fig

  2. Do comprehensive performance measurement systems help or hinder managers' mental model development?

    OpenAIRE

    Matthew Hall

    2011-01-01

    This study examines whether and how the process of updating and changing mental models (learning) helps to explain how performance measurement systems (PMS) affect individual performance. Although prior studies (e.g., Hall, 2008; Burney and Widener, 2007; Burney et al., 2009) highlight the important role of particular cognitive and motivational mechanisms, such as role clarity and organizational justice, they do not consider how PMS can improve performance by helping individuals to update the...

  3. Comprehensive System-Based Architecture for an Integrated High Energy Laser Test Bed

    Science.gov (United States)

    2015-03-01

    Weapons Station NBVC Naval Base Ventura County NOAA National Oceanic and Atmospheric Administration NOHD Nominal Ocular Hazard Distance xix NOMADS ...sensor similar to how a digital camera measures photons encountering its Charge-Coupled Detector (CCD) mechanism. The intensity of light energy...NOAA) Operational Model Archive Distribution System ( NOMADS ), in order to supply up-to-date predictions out to 180 hours of the planned test event

  4. Comprehensive Reproductive System Care Program - Clinical Breast Care Project (CRSCP-CBCP)

    Science.gov (United States)

    2013-01-01

    biomedical informatics group here, the ProLogic team, and the MDR Global leader. This Pathology Checklist tablet data capturing system development with...initiative in developing a prototype tablet application using the Pathology Checklist as the first example following a decision made at the last CBCP...enabling surgery within the center. The Breast Imaging Center has a designated Aurora Breast MRI machine. The merging of the Army and Navy Breast

  5. S-type and P-type habitability in stellar binary systems: A comprehensive approach. I. Method and applications

    Energy Technology Data Exchange (ETDEWEB)

    Cuntz, M., E-mail: cuntz@uta.edu [Department of Physics, University of Texas at Arlington, Arlington, TX 76019-0059 (United States)

    2014-01-01

    A comprehensive approach is provided for the study of both S-type and P-type habitability in stellar binary systems, which in principle can also be expanded to systems of higher order. P-type orbits occur when the planet orbits both binary components, whereas in the case of S-type orbits, the planet orbits only one of the binary components with the second component considered a perturbator. The selected approach encapsulates a variety of different aspects, which include: (1) the consideration of a joint constraint, including orbital stability and a habitable region for a putative system planet through the stellar radiative energy fluxes ({sup r}adiative habitable zone{sup ;} RHZ), needs to be met; (2) the treatment of conservative, general, and extended zones of habitability for the various systems as defined for the solar system and beyond; (3) the provision of a combined formalism for the assessment of both S-type and P-type habitability; in particular, mathematical criteria are presented for the kind of system in which S-type and P-type habitability is realized; (4) applications of the attained theoretical approach to standard (theoretical) main-sequence stars. In principle, five different cases of habitability are identified, which are S-type and P-type habitability provided by the full extent of the RHZs; habitability, where the RHZs are truncated by the additional constraint of planetary orbital stability (referred to as ST- and PT-type, respectively); and cases of no habitability at all. Regarding the treatment of planetary orbital stability, we utilize the formulae of Holman and Wiegert as also used in previous studies. In this work, we focus on binary systems in circular orbits. Future applications will also consider binary systems in elliptical orbits and provide thorough comparisons to other methods and results given in the literature.

  6. Assessment of training needs and preferences for geographic information systems (GIS) mapping in state comprehensive cancer-control programs.

    Science.gov (United States)

    Hopfer, Suellen; Chadwick, Amy E; Parrott, Roxanne L; Ghetian, Christie B; Lengerich, Eugene J

    2009-10-01

    Geographic information systems (GIS) mapping technologies have potential to advance public health promotion by mapping regional differences in attributes (e.g., disease burden, environmental exposures, access to health care services) to suggest priorities for public health interventions. Training in GIS for comprehensive cancer control (CCC) has been overlooked. State CCC programs' GIS training needs were assessed by interviewing 49 state CCC directors. A majority perceived a need for GIS training, slightly more than half of state CCC programs had access to geocoded data, and the majority of programs did not require continuing education credits of their staff. CCC directors perceived judging maps and realizing their limitations as important skills and identified epidemiologists, CCC staff, public health officials, policy makers, and cancer coalition members as training audiences. They preferred in-class training sessions that last a few hours to a day. Lessons learned are shared to develop training programs with translatable GIS skills for CCC.

  7. Comprehensive evaluation of carboxylated nanodiamond as a topical drug delivery system.

    Science.gov (United States)

    Lim, Dae Gon; Kim, Ki Hyun; Kang, Eunah; Lim, Sun Hee; Ricci, Jeremy; Sung, Si Kwon; Kwon, Myoung Taek; Jeong, Seong Hoon

    2016-01-01

    The best strategy in the development of topical drug delivery systems may be to facilitate the permeation of drugs without any harmful effects, while staying on the skin surface and maintaining stability of the system. Nanodiamonds (NDs) play a key role with their excellent physicochemical properties, including high biocompatibility, physical adsorption, reactive oxygen species (ROS) scavenging capability, and photostabilizing activity. Z-average sizes of carboxylated ND (ND-COOH) agglutinate decreased significantly as the pH increased. Fluorescein-conjugated ND was observed only on the stratum corneum, and no sample diffused into the dermal layer even after 48 hours. Moreover, ND-COOH and ND-COOH/eugenol complex did not show significant toxic effects on murine macrophage cells. ND improved in vitro skin permeation >50% acting as a "drug reservoir" to maintain a high drug concentration in the donor chamber, which was supported by quartz crystal microbalance results. Moreover, ND-COOH could adsorb a drug amount equivalent to 80% of its own weight. A photostability study showed that ND-COOH increased the photostability ~47% with regard to rate constant of the eugenol itself. A significant decrease in ROS was observed in the ND-COOH and ND-COOH/eugenol complex compared with the negative control during intracellular ROS assay. Moreover, ROS and cupric reducing antioxidant capacity evaluation showed that ND-COOH had synergistic effects of antioxidation with eugenol. Therefore, ND-COOH could be used as an excellent topical drug delivery system with improved permeability, higher stability, and minimized safety issue.

  8. Measuring Listening Comprehension Skills of 5th Grade School Students with the Help of Web Based System

    Directory of Open Access Journals (Sweden)

    M. Bahaddin Acat

    2016-01-01

    Full Text Available The main purpose of this study is to measure listening comprehension skills of 5th grade school students with the help of web based system. This study was conducted on 5th grade students studying at the primary schools of Eskisehir. The scale used in the process of the study is “Web Based Listening Scale”. In the process of the study, it was investigated that the level of differentiation listening skill and educational level of mother and father, family income level, Turkish Course grading note, the most popular and listened music genre. According to the results obtained that significant difference was found with listening skills and educational level of mother and father, family income level and the most popular and listened music genre. Also it was found that there is powerful relationship between listening skills and Turkish Course grading note. In the process of the research, it was observed the students used the web based system more attentive and motivated. Nevertheless, personalized measuring environment was provided by the web based system. Finally, it can be said that the web based systems can be used positively for language learning, teaching, and instruction, improving, measuring and assessing process.

  9. Making the CARE Comprehensive Geriatric Assessment as the Core of a Total Mobile Long Term Care Support System in China.

    Science.gov (United States)

    Cui, Yanyan; Gong, Dongwei; Yang, Bo; Chen, Hua; Tu, Ming-Hsiang; Zhang, Chaonan; Li, Huan; Liang, Naiwen; Jiang, Liping; Chang, Polun

    2018-01-01

    Comprehensive Geriatric Assessments (CGAs) have been recommended to be used for better monitoring the health status of elder residents and providing quality care. This study reported how our nurses perceived the usability of CGA component of a mobile integrated-care long term care support system developed in China. We used the Continuity Assessment Record and Evaluation (CARE), developed in the US, as the core CGA component of our Android-based support system, in which apps were designed for all key stakeholders for delivering quality long term care. A convenience sample of 18 subjects from local long term care facilities in Shanghai, China were invited to assess the CGA assessment component in terms of Technology Acceptance Model for Mobile based on real field trial assessment. All (100%) were satisfied with the mobile CGA component. 88.9% perceived the system was easy to learn and use. 99.4% showed their willingness to use for their work. We concluded it is technically feasible to implement a CGA-based mobile integrated care support system in China.

  10. A comprehensive evaluation of the PRESAGE/optical-CT 3D dosimetry system

    Energy Technology Data Exchange (ETDEWEB)

    Sakhalkar, H. S.; Adamovics, J.; Ibbott, G.; Oldham, M. [Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina 27710 (United States); Department of Chemistry and Biology, Rider University, Lawrenceville, New Jersey 08648 (United States); Department of Radiation Physics, M. D. Anderson Cancer Center, Houston, Texas 77030 (United States); Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina 27710 (United States)

    2009-01-15

    This work presents extensive investigations to evaluate the robustness (intradosimeter consistency and temporal stability of response), reproducibility, precision, and accuracy of a relatively new 3D dosimetry system comprising a leuco-dye doped plastic 3D dosimeter (PRESAGE) and a commercial optical-CT scanner (OCTOPUS 5x scanner from MGS Research, Inc). Four identical PRESAGE 3D dosimeters were created such that they were compatible with the Radiologic Physics Center (RPC) head-and-neck (H and N) IMRT credentialing phantom. Each dosimeter was irradiated with a rotationally symmetric arrangement of nine identical small fields (1x3 cm{sup 2}) impinging on the flat circular face of the dosimeter. A repetitious sequence of three dose levels (4, 2.88, and 1.28 Gy) was delivered. The rotationally symmetric treatment resulted in a dose distribution with high spatial variation in axial planes but only gradual variation with depth along the long axis of the dosimeter. The significance of this treatment was that it facilitated accurate film dosimetry in the axial plane, for independent verification. Also, it enabled rigorous evaluation of robustness, reproducibility and accuracy of response, at the three dose levels. The OCTOPUS 5x commercial scanner was used for dose readout from the dosimeters at daily time intervals. The use of improved optics and acquisition technique yielded substantially improved noise characteristics (reduced to {approx}2%) than has been achieved previously. Intradosimeter uniformity of radiochromic response was evaluated by calculating a 3D gamma comparison between each dosimeter and axially rotated copies of the same dosimeter. This convenient technique exploits the rotational symmetry of the distribution. All points in the gamma comparison passed a 2% difference, 1 mm distance-to-agreement criteria indicating excellent intradosimeter uniformity even at low dose levels. Postirradiation, the dosimeters were all found to exhibit a slight increase in

  11. A comprehensive evaluation of the PRESAGE/optical-CT 3D dosimetry system

    International Nuclear Information System (INIS)

    Sakhalkar, H. S.; Adamovics, J.; Ibbott, G.; Oldham, M.

    2009-01-01

    This work presents extensive investigations to evaluate the robustness (intradosimeter consistency and temporal stability of response), reproducibility, precision, and accuracy of a relatively new 3D dosimetry system comprising a leuco-dye doped plastic 3D dosimeter (PRESAGE) and a commercial optical-CT scanner (OCTOPUS 5x scanner from MGS Research, Inc). Four identical PRESAGE 3D dosimeters were created such that they were compatible with the Radiologic Physics Center (RPC) head-and-neck (H and N) IMRT credentialing phantom. Each dosimeter was irradiated with a rotationally symmetric arrangement of nine identical small fields (1x3 cm 2 ) impinging on the flat circular face of the dosimeter. A repetitious sequence of three dose levels (4, 2.88, and 1.28 Gy) was delivered. The rotationally symmetric treatment resulted in a dose distribution with high spatial variation in axial planes but only gradual variation with depth along the long axis of the dosimeter. The significance of this treatment was that it facilitated accurate film dosimetry in the axial plane, for independent verification. Also, it enabled rigorous evaluation of robustness, reproducibility and accuracy of response, at the three dose levels. The OCTOPUS 5x commercial scanner was used for dose readout from the dosimeters at daily time intervals. The use of improved optics and acquisition technique yielded substantially improved noise characteristics (reduced to ∼2%) than has been achieved previously. Intradosimeter uniformity of radiochromic response was evaluated by calculating a 3D gamma comparison between each dosimeter and axially rotated copies of the same dosimeter. This convenient technique exploits the rotational symmetry of the distribution. All points in the gamma comparison passed a 2% difference, 1 mm distance-to-agreement criteria indicating excellent intradosimeter uniformity even at low dose levels. Postirradiation, the dosimeters were all found to exhibit a slight increase in

  12. FIELD TEST PROGRAM TO DEVELOP COMPREHENSIVE DESIGN, OPERATING, AND COST DATA FOR MERCURY CONTROL SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Michael D. Durham

    2003-05-01

    With the Nation's coal-burning utilities facing the possibility of tighter controls on mercury pollutants, the U.S. Department of Energy is funding projects that could offer power plant operators better ways to reduce these emissions at much lower costs. Mercury is known to have toxic effects on the nervous system of humans and wildlife. Although it exists only in trace amounts in coal, mercury is released when coal burns and can accumulate on land and in water. In water, bacteria transform the metal into methylmercury, the most hazardous form of the metal. Methylmercury can collect in fish and marine mammals in concentrations hundreds of thousands times higher than the levels in surrounding waters. One of the goals of DOE is to develop technologies by 2005 that will be capable of cutting mercury emissions 50 to 70 percent at well under one-half of today's costs. ADA Environmental Solutions (ADA-ES) is managing a project to test mercury control technologies at full scale at four different power plants from 2000--2003. The ADA-ES project is focused on those power plants that are not equipped with wet flue gas desulfurization systems. ADA-ES has developed a portable system that will be tested at four different utility power plants. Each of the plants is equipped with either electrostatic precipitators or fabric filters to remove solid particles from the plant's flue gas. ADA-ES's technology will inject a dry sorbent, such as activated carbon, which removes the mercury and makes it more susceptible to capture by the particulate control devices. A fine water mist may be sprayed into the flue gas to cool its temperature to the range where the dry sorbent is most effective. PG&E National Energy Group is providing two test sites that fire bituminous coals and both are equipped with electrostatic precipitators and carbon/ash separation systems. Wisconsin Electric Power Company is providing a third test site that burns Powder River Basin (PRB) coal and

  13. Comprehensive characterization of ball-milled powders simulating a tribofilm system

    Energy Technology Data Exchange (ETDEWEB)

    Häusler, I., E-mail: ines.haeusler@bam.de; Dörfel, I., E-mail: Ilona.doerfel@bam.de; Peplinski, B., E-mail: Burkhard.peplinski@bam.de; Dietrich, P.M., E-mail: Paul.dietrich@yahoo.de; Unger, W.E.S., E-mail: Wolfgang.Unger@bam.de; Österle, W., E-mail: Werner.Oesterle@bam.de

    2016-01-15

    A model system was used to simulate the properties of tribofilms which form during automotive braking. The model system was prepared by ball milling of a blend of 70 vol.% iron oxides, 15 vol.% molybdenum disulfide and 15 vol.% graphite. The resulting mixture was characterized by X-ray powder diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and various transmission electron microscopic (TEM) methods, including energy dispersive X-ray spectroscopy (EDXS), high resolution investigations (HRTEM) with corresponding simulation of the HRTEM images, diffraction methods such as scanning nano-beam electron diffraction (SNBED) and selected area electron diffraction (SAED). It could be shown that the ball milling caused a reduction of the grain size of the initial components to the nanometer range. Sometimes even amorphization or partial break-down of the crystal structure was observed for MoS{sub 2} and graphite. Moreover, chemical reactions lead to a formation of surface coverings of the nanoparticles by amorphous material, molybdenum oxides, and iron sulfates as derived from XPS. - Highlights: • Ball milling of iron oxides, MoS{sub 2}, and graphite to simulate a tribofilm • Increasing coefficient of friction after ball milling of the model blend • Drastically change of the diffraction pattern of the powder mixture • TEM & XPS showed the components of the milled mixture and the process during milling. • MoS{sub 2} and graphite suffered a loss in translation symmetry or became amorphous.

  14. Grasping Ideas with the Motor System: Semantic Somatotopy in Idiom Comprehension

    Science.gov (United States)

    Hauk, Olaf; Pulvermüller, Friedemann

    2009-01-01

    Single words and sentences referring to bodily actions activate the motor cortex. However, this semantic grounding of concrete language does not address the critical question whether the sensory–motor system contributes to the processing of abstract meaning and thought. We examined functional magnetic resonance imaging activation to idioms and literal sentences including arm- and leg-related action words. A common left fronto-temporal network was engaged in sentence reading, with idioms yielding relatively stronger activity in (pre)frontal and middle temporal cortex. Crucially, somatotopic activation along the motor strip, in central and precentral cortex, was elicited by idiomatic and literal sentences, reflecting the body part reference of the words embedded in the sentences. Semantic somatotopy was most pronounced after sentence ending, thus reflecting sentence-level processing rather than that of single words. These results indicate that semantic representations grounded in the sensory–motor system play a role in the composition of sentence-level meaning, even in the case of idioms. PMID:19068489

  15. Interstitial lung disease in systemic autoimmune rheumatic diseases: a comprehensive review.

    Science.gov (United States)

    Atzeni, Fabiola; Gerardi, Maria Chiara; Barilaro, Giuseppe; Masala, Ignazio Francesco; Benucci, Maurizio; Sarzi-Puttini, Piercarlo

    2018-01-01

    Interstitial lung diseases (ILDs) are among the most serious complications associated with systemic rheumatic diseases, and lead to significant morbidity and mortality; they may also be the first manifestation of connective tissue diseases (CTDs). The aim of this narrative review is to summarise the data concerning the pathogenesis of CTD/ILD and its distinguishing features in different rheumatic diseseas. Areas covered: The pathogenesis, clinical aspects and treatment of ILD associated with rheumatic systemic diseases and CTDs were reviewed by searching the PubMed, Medline, and Cochrane Library databases for papers published between 1995 and February 2017 using combinations of words or terms. Articles not written in English were excluded. Expert commentary: The management of CTD-ILD is challenging because of the lack of robust data regarding the treatments used, the heterogeneity of the diseases themselves, and the scarcity of well-defined outcome measures. Treatment decisions are often made clinically on the basis of functional, radiographic progression, and exacerbating factors such as age and the burden of comorbidities. Given the complexities of diagnosis and the paucity of treatment trials, the management of CTD patients with ILD requires multidisciplinary collaboration between rheumatologists and pulmonologists in CTD-ILD clinics.

  16. Comprehensive long distance and real-time pipeline monitoring system based on fiber optic sensing

    Energy Technology Data Exchange (ETDEWEB)

    Nikles, Marc; Ravet, Fabien; Briffod, Fabien [Omnisens S.A., Morges (Switzerland)

    2009-07-01

    An increasing number of pipelines are constructed in remote regions affected by harsh environmental conditions. These pipeline routes often cross mountain areas which are characterized by unstable grounds and where soil texture changes between winter and summer increase the probability of hazards. Due to the long distances to be monitored and the linear nature of pipelines, distributed fiber optic sensing techniques offer significant advantages and the capability to detect and localize pipeline disturbance with great precision. Furthermore pipeline owner/operators lay fiber optic cable parallel to transmission pipelines for telecommunication purposes and at minimum additional cost monitoring capabilities can be added to the communication system. The Brillouin-based Omnisens DITEST monitoring system has been used in several long distance pipeline projects. The technique is capable of measuring strain and temperature over 100's kilometers with meter spatial resolution. Dedicated fiber optic cables have been developed for continuous strain and temperature monitoring and their deployment along the pipeline has enabled permanent and continuous pipeline ground movement, intrusion and leak detection. This paper presents a description of the fiber optic Brillouin-based DITEST sensing technique, its measurement performance and limits, while addressing future perspectives for pipeline monitoring. (author)

  17. The internal rate of return of photovoltaic grid-connected systems. A comprehensive sensitivity analysis

    International Nuclear Information System (INIS)

    Talavera, D.L.; Nofuentes, G.; Aguilera, J.

    2010-01-01

    At present, photovoltaic grid-connected systems (PVGCS) are experiencing a formidable market growth. This is mainly due to a continuous downward trend in PV cost together with some government support programmes launched by many developed countries. However, government bodies and prospective owners/investors are concerned with how changes in existing economic factors - financial incentives and main economic parameters of the PVGCS - that configure a given scenario may affect the profitability of the investment in these systems. Consequently, not only is a mere estimate of the economic profitability in a specific moment required, but also how this profitability may vary according to changes in the existing scenario. In order to enlighten decision-makers and prospective owners/investors of PVGCS, a sensitivity analysis of the internal rate of return (IRR) to some economic factors has been carried out. Three different scenarios have been assumed to represent the three top geographical markets for PV: the Euro area, the USA and Japan. The results obtained in this analysis provide clear evidence that annual loan interest, normalised initial investment subsidy, normalised annual PV electricity yield, PV electricity unitary price and normalised initial investment are ordered from the lowest to the highest impact on the IRR. A short and broad analysis concerning the taxation impact is also provided. (author)

  18. Assessing the Sustainability of Decentralized Renewable Energy Systems: A Comprehensive Framework with Analytical Methods

    Directory of Open Access Journals (Sweden)

    Aparna Katre

    2018-04-01

    Full Text Available The number of models of Decentralized Renewable Energy (DRE systems, particularly for rural electrification, is growing globally. Most approaches to assess the sustainability of these solutions beyond simple techno-economic considerations are comparative in nature, and only allow us to evaluate performance within a set of other interventions. This leaves a gap in our understanding of the conditions for a specific model to be sustainable and whether its replication is likely to succeed. The approach suggested develops a framework to evaluate the sustainability of specific models for energy access individually and proposes analytical methods to illustrate its use. It combines the multi-dimensional analysis over five sustainability dimensions and the Multi-Tier Framework (MTF to assess technical sustainability, extending MTF’s rigorous scoring methodology to the other dimensions. The scores are based on qualitative and quantitative data collected from key stakeholders, taking into account different perspectives and aims. The framework and analytical methods are exemplified using a subset of data collected in over 40 off-grid DRE systems utilizing a common community ownership and hybrid financial structure. The proposed methodology can be used to understand the sustainability conditions of a given approach to energy access and can therefore be used by practitioners and policy makers to develop strategies and guide policies to roll out effective solutions.

  19. Comprehensive thermodynamic description of the quasiternary system PbTe-GeTe-SnTe

    International Nuclear Information System (INIS)

    Yashina, Lada V.; Leute, Volkmar; Shtanov, Vladimir I.; Schmidtke, Heinrich M.; Neudachina, Vera S.

    2006-01-01

    The equilibrium phase diagram of the quasiternary system PbTe-GeTe-SnTe was studied experimentally in the ranges of spinodal demixing and (solid + liquid) equilibrium by means of X-ray diffraction (XRD), electron microprobe analysis (EMA) and differential thermal analysis (DTA). A model description of the phase diagram was done on the base of composition dependent interaction parameters, which were determined for the solid and the liquid phases. The interaction parameters for the quasibinary systems were recalculated in order to reach better correlation between all experimental data. It was shown that the quasiternary phase diagram can be principally described using the interaction parameters for the quasibinary subsystems, but an additional ternary interaction parameter has also to be considered. The local structure of the quasiternary solid solution is described by a four-particle cluster model. Due to the tendency of the solid solution to demix, the probability of the (GeGeGe)Te cluster was found to be higher and that of the (PbGeGe)Te cluster to be lower than it is expected for the purely statistical distribution of the clusters

  20. Comprehensive evaluation of carboxylated nanodiamond as a topical drug delivery system

    Directory of Open Access Journals (Sweden)

    Lim DG

    2016-05-01

    Full Text Available Dae Gon Lim,1,* Ki Hyun Kim,1,* Eunah Kang,2 Sun Hee Lim,3 Jeremy Ricci,3 Si Kwon Sung,3 Myoung Taek Kwon,3 Seong Hoon Jeong1 1College of Pharmacy, Dongguk University-Seoul, Gyeonggi, 2School of Chemical Engineering and Material Science, Chung-Ang University, 3NanoResource Co. Ltd., Seoul, Republic of Korea *These authors contributed equally to this work Abstract: The best strategy in the development of topical drug delivery systems may be to facilitate the permeation of drugs without any harmful effects, while staying on the skin surface and maintaining stability of the system. Nanodiamonds (NDs play a key role with their excellent physicochemical properties, including high biocompatibility, physical adsorption, reactive oxygen species (ROS scavenging capability, and photostabilizing activity. Z-average sizes of carboxylated ND (ND–COOH agglutinate decreased significantly as the pH increased. Fluorescein-conjugated ND was observed only on the stratum corneum, and no sample diffused into the dermal layer even after 48 hours. Moreover, ND–COOH and ND–COOH/eugenol complex did not show significant toxic effects on murine macrophage cells. ND improved in vitro skin permeation >50% acting as a “drug reservoir” to maintain a high drug concentration in the donor chamber, which was supported by quartz crystal microbalance results. Moreover, ND–COOH could adsorb a drug amount equivalent to 80% of its own weight. A photostability study showed that ND–COOH increased the photostability ~47% with regard to rate constant of the eugenol itself. A significant decrease in ROS was observed in the ND–COOH and ND–COOH/eugenol complex compared with the negative control during intracellular ROS assay. Moreover, ROS and cupric reducing antioxidant capacity evaluation showed that ND–COOH had synergistic effects of antioxidation with eugenol. Therefore, ND–COOH could be used as an excellent topical drug delivery system with improved permeability

  1. Comprehensive approach to the assessment of nanosized fractions of polydisperse systems of crushed rocks

    Directory of Open Access Journals (Sweden)

    DANILOV Victor Evgenyevich

    2016-06-01

    Full Text Available The results of size determination for mechanically dispersed rock (polymineral sand, basalt based on methods of dynamic light scattering, gas (nitrogen sorption and electron microscopy were comparatively analyzed. The experimental samples are obtained by mechanical dispersion of raw materials on the planetary and colloidal grinding mills. There is a high correlation in the obtained experimental results. Method of dynamic light scattering makes it possible to analyze dimensional characteristics of polydispersed systems with high amount of nano- and submicron particles with sufficient sedimentation stability in the dispersion medium. Characteristics of particles size calculated by the specific surface area of the studied systems’ consider the content of the micro-size fraction. The effective diameter of the particles was proposed as the characteristics of their morphological structure. The calculation of the effective diameter is based on the particle mass.

  2. A comprehensive guide for designing more efficient irrigation systems with respect to application control

    Science.gov (United States)

    Khaddam, Issam; Schuetze, Niels

    2017-04-01

    The worldwide water scarcity problems are expected to aggravate due to the increasing population and the need to produce more food. Irrigated agriculture is considered the highest consumer of fresh water resources with a rate exceeds 70% of global consumption. Consequently, an improvement in the efficiency of all irrigation methods, such as furrow or drip irrigation, becomes more necessary and urgent. Therefore, a more precise knowledge about soil water distribution in the root zone and the water balance components is required. For this purpose and as a part of the SAPHIR project (Saxonian Platform for high Performance Irrigation), a 2D simulation- based study was performed with virtual field conditions. The study investigates the most important design parameters of many irrigation systems, such as irrigation intensity and duration, and shows there influence on the water distribution efficiency. Furthermore, three main soil textures are used to test the impact of the soil hydraulic properties on irrigation effectiveness. A numerous number of irrigation scenarios of each irrigation system was simulated using HYDRUS 2D. Thereafter, the results were digitally calculated, compiled and made available online in the so called "Irrigation Atlases". The irrigation atlases provide graphical results of the soil moisture and pressure head distributions in the root zone. Moreover, they contain detailed information of the water balance for all simulated scenarios. The most studies evaluate the irrigation water demands on local, regional or global scales and for that an efficient water distribution is required. In this context, the irrigation atlases can serve as a valuable tool for the implementation of planned irrigation measures.

  3. A comprehensive information technology system to support physician learning at the point of care.

    Science.gov (United States)

    Cook, David A; Sorensen, Kristi J; Nishimura, Rick A; Ommen, Steve R; Lloyd, Farrell J

    2015-01-01

    MayoExpert is a multifaceted information system integrated with the electronic medical record (EMR) across Mayo Clinic's multisite health system. It was developed as a technology-based solution to manage information, standardize clinical practice, and promote and document learning in clinical contexts. Features include urgent test result notifications; models illustrating expert-approved care processes; concise, expert-approved answers to frequently asked questions (FAQs); a directory of topic-specific experts; and a portfolio for provider licensure and credentialing. The authors evaluate MayoExpert's reach, effectiveness, adoption, implementation, and maintenance. Evaluation data sources included usage statistics, user surveys, and pilot studies.As of October 2013, MayoExpert was available at 94 clinical sites in 12 states and contained 1,368 clinical topics, answers to 7,640 FAQs, and 92 care process models. In 2012, MayoExpert was accessed at least once by 2,578/3,643 (71%) staff physicians, 900/1,374 (66%) midlevel providers, and 1,728/2,291 (75%) residents and fellows. In a 2013 survey of MayoExpert users with 536 respondents, all features were highly rated (≥67% favorable). More providers reported using MayoExpert to answer questions before/after than during patient visits (68% versus 36%). During November 2012 to April 2013, MayoExpert sent 1,660 notifications of new-onset atrial fibrillation and 1,590 notifications of prolonged QT. MayoExpert has become part of routine clinical and educational operations, and its care process models now define Mayo Clinic best practices. MayoExpert's infrastructure and content will continue to expand with improved templates and content organization, new care process models, additional notifications, better EMR integration, and improved support for credentialing activities.

  4. Maternal, Fetal and Neonatal Outcomes in Pregnant Women with Systemic Lupus Erythematosus: A Comprehensive Review Study

    Directory of Open Access Journals (Sweden)

    Fatemeh Zahra Karimi

    2017-11-01

    Full Text Available Background:Systemic lupus erythematosus (SLE is an autoimmune disease with multiple organ involvement and periods of relapse and remission that mainly affects young women of childbearing age. In this regard the reproductive health is an important issue. Although diagnosis, treatment and management of pregnancy in SLE women have been improved recently, but the main concern is effects of SLE on maternal, fetal and neonatal outcomes. This study aimed to investigate the maternal, fetal and neonatal outcomes in pregnant women with SLE. Materials and Methods: The databases of PubMed, Medline, Scopus and Web of Science as well as domestic database (Persian such as SID, Magiran, Irandoc, and Google Scholar were searched with using keywords such as" Systemic lupus erythematosus"; "Pregnancy"; "Neonatal lupus"; "maternal, fetus or neonatal outcome";  and equivalent Persian words. Included were all Persian and English articles, published between 2000 and May 2017. Finally, a total of 77 studies were included. Results: Adverse perinatal outcomes increase in pregnancies with lupus. Outcomes include respiratory, cardiovascular, blood and skin disorders in mothers; stillbirth, spontaneous, and recurrent abortion in fetuses and neonatal lupus, prematurity, intrauterine growth restriction (IUGR, and small for gestational age (SGA in neonates, respectively. Conclusion: Pregnant women with SLE are at high risk due to increased complications for both mother and fetus. It seems broad control of the women before fertilization, so that they be at full remission in the beginning of pregnancy and the disease activity be in complete control, it can help to improve outcomes of pregnancy and so better results can be expected.

  5. The Role and Immunobiology of Eosinophils in the Respiratory System: a Comprehensive Review.

    Science.gov (United States)

    Eng, Stephanie S; DeFelice, Magee L

    2016-04-01

    The eosinophil is a fully delineated granulocyte that disseminates throughout the bloodstream to end-organs after complete maturation in the bone marrow. While the presence of eosinophils is not uncommon even in healthy individuals, these granulocytes play a central role in inflammation and allergic processes. Normally appearing in smaller numbers, higher levels of eosinophils in the peripheral blood or certain tissues typically signal a pathologic process. Eosinophils confer a beneficial effect on the host by enhancing immunity against molds and viruses. However, tissue-specific elevation of eosinophils, particularly in the respiratory system, can cause a variety of short-term symptoms and may lead to long-term sequelae. Eosinophils often play a role in more commonly encountered disease processes, such as asthma and allergic responses in the upper respiratory tract. They are also integral in the pathology of less common diseases including eosinophilic pneumonia, allergic bronchopulmonary aspergillosis, hypersensitivity pneumonitis, and drug reaction with eosinophilia and systemic symptoms. They can be seen in neoplastic disorders or occupational exposures as well. The involvement of eosinophils in pulmonary disease processes can affect the method of diagnosis and the selection of treatment modalities. By analyzing the complex interaction between the eosinophil and its environment, which includes signaling molecules and tissues, different therapies have been discovered and created in order to target disease processes at a cellular level. Innovative treatments such as mepolizumab and benralizumab will be discussed. The purpose of this article is to further explore the topic of eosinophilic presence, activity, and pathology in the respiratory tract, as well as discuss current and future treatment options through a detailed literature review.

  6. Photobiology, photodermatology and sunscreens: a comprehensive overview. Part 2: topical and systemic photoprotection.

    Science.gov (United States)

    Celleno, L; Calzavara-Pinton, P; Sala, R; Arisi, M C; Bussoletti, C

    2013-02-01

    Sun exposure of the skin triggers several inflammatory pathways via a multitude of photochemical and photobiological effects. Furthermore, local and systemic immune suppression develops. The main clinical effects of UV exposure can be classified schematically into immediate, including sunburn, tanning, vitamin D production and exacerbation of inherited and acquired photosensitive skin disorders and long-term, including solar ageing and skin cancer. The protection against solar radiation is afforded by a healthy behavior of reasonable sun avoidance and the use of topical sunscreens as well as topical and oral antioxidants. However, users of sunscreen products should be able to choose correctly the most convenient product according to their needs. In Europe, the sun protection factor (SPF) and the UVA-protection factor (UVA-PF) are labeled to indicate the degree of protection against UVB and UVA, respectively. However, dermatologists must be aware that the present knowledge of UV effects on human skin needs to be clarified and several regulatory issues of photo-protection remain to be clarified and standardized. Finally, much work is needed to improve water resistance, spreadability, transparency and homogeneity of the sunscreen agents.

  7. The Comprehensive Biomechanics and Load-Sharing of Semirigid PEEK and Semirigid Posterior Dynamic Stabilization Systems

    Directory of Open Access Journals (Sweden)

    D. K. Sengupta

    2013-01-01

    Full Text Available Alternatives to conventional rigid fusion have been proposed for several conditions related to degenerative disc disease when nonoperative treatment has failed. Semirigid fixation, in the form of dynamic stabilization or PEEK rods, is expected to provide compression under loading as well as an intermediate level of stabilization. This study systematically examines both the load-sharing characteristics and kinematics of these two devices compared to the standard of internal rigid fixators. Load-sharing was studied by using digital pressure films inserted between an artificially machined disc and two loading fixtures. Rigid rods, PEEK rods, and the dynamic stabilization system were inserted posteriorly for stabilization. The kinematics were quantified on ten, human, cadaver lumbosacral spines (L3-S1 which were tested under a pure bending moment, in flexion-extension, lateral bending, and axial rotation. The magnitude of load transmission through the anterior column was significantly greater with the dynamic device compared to PEEK rods and rigid rods. The contact pressures were distributed more uniformly, throughout the disc with the dynamic stabilization devices, and had smaller maximum point-loading (pressures on any particular point within the disc. Kinematically, the motion was reduced by both semirigid devices similarly in all directions, with slight rigidity imparted by a lateral interbody device.

  8. MAHA: A comprehensive system for the storage and visualization of subsoil data for seismic microzonation

    Science.gov (United States)

    Di Felice, P.; Spadoni, M.

    2013-04-01

    MAHA is a database-centred software system for the storage and visualization of subsoil data used for the production of seismic microzonation maps in Italy. The application was implemented using open source software in order to grant its maximum diffusion and customization. A conceptual model of the subsoil, jointly developed by the Italian National Research Council and the National Department of Civil Protection, inspired the structure of the underlying database, consisting of 15 tables, 3 of which of spatial nature to accommodate geo-referenced data associated to points, lines and polygons. A web-GIS interface acts as a bridge between the user and the database, drives the input of geo-referenced data and enables the users to formulate different types of spatial queries. A series of forms designed "ad hoc" and enriched with combo boxes provide guided procedures to maximize the fluency of data entry and to reduce the possibility of erroneous typing. One of these procedures helps to transform the descriptions of the geological units (granular materials), given in technical paper documents by using a conversational style, into standardized numeric codes. Summary reports, produced in the pdf format, can be generated through decoding and graphic display of the parameters previously entered in the database. MAHA was approved by the national commission for seismic microzonation established by the Italian Prime Minister and, in the next years, it is expected to significantly support the entire process of map production in the urban areas more exposed to seismic hazard.

  9. A Comprehensive System of Energy Intensity Indicators for the U.S.: Methods, Data and Key Trends

    Energy Technology Data Exchange (ETDEWEB)

    Belzer, David B.

    2014-08-31

    This report describes a comprehensive system of energy intensity indicators for the United States that has been developed for the Department of Energy’s Office of Energy Efficiency and Renewable Energy (EERE) over the past decade. This system of indicators is hierarchical in nature, beginning with detailed indexes of energy intensity for various sectors of the economy, which are ultimately aggregated to an overall energy intensity index for the economy as a whole. The aggregation of energy intensity indexes to higher levels in the hierarchy is performed with a version of the Log Mean Divisia Index (LMDI) method. Based upon the data and methods in the system of indicators, the economy-wide energy intensity index shows a decline of about 14% in 2010 relative to a 1985 base year. Discussion of energy intensity indicators for each of the broad end-use sectors of the economy—residential, commercial, industrial, and transportation—is presented in the report. An analysis of recent changes in the efficiency of electricity generation in the U.S. is also included. A detailed appendix describes the data sources and methodology behind the energy intensity indicators for each sector.

  10. Chemical Industry Corrosion Management: A Comprehensive Information System (ASSET 2). Final Report

    Energy Technology Data Exchange (ETDEWEB)

    John, Randy C. [Shell Global Solutions, Houston, TX (United States); Young, Arthur L. [Humberside Solutions, Toronto, ON (Canada); Pelton, Arthur D. [CRCT, Ecole Polytechnique de Montreal, Quebec (Canada); Thompson, William T. [Royal Military College of Canada, Kingston, ON (Canada); Wright, Ian G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2008-10-10

    The research sponsored by this project has greatly expanded the ASSET corrosion prediction software system to produce a world-class technology to assess and predict engineering corrosion of metals and alloys corroding by exposure to hot gases. The effort included corrosion data compilation from numerous industrial sources and data generation at Shell Oak Ridge National Laboratory and several other companies for selected conditions. These data were organized into groupings representing various combinations of commercially available alloys and corrosion by various mechanisms after acceptance via a critical screening process to ensure the data were for alloys and conditions, which were adequately well defined, and of sufficient repeatability. ASSET is the largest and most capable, publicly-available technology in the field of corrosion assessment and prediction for alloys corroding by high temperature processes in chemical plants, hydrogen production, energy conversion processes, petroleum refining, power generation, fuels production and pulp/paper processes. The problems addressed by ASSET are: determination of the likely dominant corrosion mechanism based upon information available to the chemical engineers designing and/or operating various processes and prediction of engineering metal losses and lifetimes of commercial alloys used to build structural components. These assessments consider exposure conditions (metal temperatures, gas compositions and pressures), alloy compositions and exposure times. Results of the assessments are determination of the likely dominant corrosion mechanism and prediction of the loss of metal/alloy thickness as a function of time, temperature, gas composition and gas pressure. The uses of these corrosion mechanism assessments and metal loss predictions are that the degradation of processing equipment can be managed for the first time in a way which supports efforts to reduce energy consumption, ensure structural integrity of equipment

  11. A comprehensive review of the clinical approach to pregnancy and systemic lupus erythematosus.

    Science.gov (United States)

    Lazzaroni, Maria Grazia; Dall'Ara, Francesca; Fredi, Micaela; Nalli, Cecilia; Reggia, Rossella; Lojacono, Andrea; Ramazzotto, Francesca; Zatti, Sonia; Andreoli, Laura; Tincani, Angela

    2016-11-01

    Nowadays, most of the young women affected by Systemic Lupus Erythematosus (SLE) can carry out one or more pregnancies thanks to the improvement in treatment and the consequent reduction in morbidity and mortality. Pregnancy outcome in these women has also greatly improved in the last decades. A correct timing for pregnancy (tailored on disease activity and established during a preconception counselling), together with a tight monitoring during the three trimesters and the post-partum period (to timely identify and treat possible obstetric complications or maternal disease flares), as well as the concept of multidisciplinary management, are currently milestones of the management of pregnancy in SLE patients. Nevertheless, the increasing knowledge on the compatibility of drugs with pregnancy has allowed a better treatment of these patients, by choosing medications that control maternal disease activity without harming the foetus. However, particular attention and strict monitoring should be dedicated to SLE pregnant women in particular clinical settings: patients with lupus nephritis and patients with aPL positivity or Antiphospholipid syndrome, who are at higher risk for maternal and foetal complications, but also patients with anti-Ro/SSA and/or anti-La/SSB antibodies, because of the risk of neonatal lupus. A discussion on family planning, as well as counselling on contraception, should be part of the everyday-practice for physicians caring for SLE women during their reproductive age. Another issue is the possible reduction of fertility in these women, that can be due to different reasons. Consequently, the request for assisted reproduction techniques has been increasing in the last years, so that rheumatologists and gynaecologists should be prepared to counsel SLE patients also in this particular setting. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. FIELD TEST PROGRAM TO DEVELOP COMPREHENSIVE DESIGN, OPERATING, AND COST DATA FOR MERCURY CONTROL SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Michael D. Durham

    2004-10-01

    PG&E NEG Salem Harbor Station Unit 1 was successfully tested for applicability of activated carbon injection as a mercury control technology. Test results from this site have enabled a thorough evaluation of mercury control at Salem Harbor Unit 1, including performance, estimated cost, and operation data. This unit has very high native mercury removal, thus it was important to understand the impacts of process variables on native mercury capture. The team responsible for executing this program included plant and PG&E headquarters personnel, EPRI and several of its member companies, DOE, ADA, Norit Americas, Inc., Hamon Research-Cottrell, Apogee Scientific, TRC Environmental Corporation, Reaction Engineering, as well as other laboratories. The technical support of all of these entities came together to make this program achieve its goals. Overall the objectives of this field test program were to determine the mercury control and balance-of-plant impacts resulting from activated carbon injection into a full-scale ESP on Salem Harbor Unit 1, a low sulfur bituminous-coal-fired 86 MW unit. It was also important to understand the impacts of process variables on native mercury removal (>85%). One half of the gas stream was used for these tests, or 43 MWe. Activated carbon, DARCO FGD supplied by NORIT Americas, was injected upstream of the cold side ESP, just downstream of the air preheater. This allowed for approximately 1.5 seconds residence time in the duct before entering the ESP. Conditions tested in this field evaluation included the impacts of the Selective Non-Catalytic Reduction (SNCR) system on mercury capture, of unburned carbon in the fly ash, of adjusting ESP inlet flue gas temperatures, and of boiler load on mercury control. The field evaluation conducted at Salem Harbor looked at several sorbent injection concentrations at several flue gas temperatures. It was noted that at the mid temperature range of 322-327 F, the LOI (unburned carbon) lost some of its

  13. S-TYPE AND P-TYPE HABITABILITY IN STELLAR BINARY SYSTEMS: A COMPREHENSIVE APPROACH. II. ELLIPTICAL ORBITS

    Energy Technology Data Exchange (ETDEWEB)

    Cuntz, M., E-mail: cuntz@uta.edu [Department of Physics, University of Texas at Arlington, Arlington, TX 76019-0059 (United States)

    2015-01-10

    In the first paper of this series, a comprehensive approach has been provided for the study of S-type and P-type habitable regions in stellar binary systems, which was, however, restricted to circular orbits of the stellar components. Fortunately, a modest modification of the method also allows for the consideration of elliptical orbits, which of course entails a much broader range of applicability. This augmented method is presented here, and numerous applications are conveyed. In alignment with Paper I, the selected approach considers a variety of aspects, which comprise the consideration of a joint constraint including orbital stability and a habitable region for a possible system planet through the stellar radiative energy fluxes ({sup r}adiative habitable zone{sup ;} RHZ). The devised method is based on a combined formalism for the assessment of both S-type and P-type habitability; in particular, mathematical criteria are deduced for which kinds of systems S-type and P-type habitable zones are realized. If the RHZs are truncated by the additional constraint of orbital stability, the notation of ST-type and PT-type habitability applies. In comparison to the circular case, it is found that in systems of higher eccentricity, the range of the RHZs is significantly reduced. Moreover, for a considerable number of models, the orbital stability constraint also reduces the range of S-type and P-type habitability. Nonetheless, S-, P-, ST-, and PT-type habitability is identified for a considerable set of system parameters. The method as presented is utilized for BinHab, an online code available at The University of Texas at Arlington.

  14. S-TYPE AND P-TYPE HABITABILITY IN STELLAR BINARY SYSTEMS: A COMPREHENSIVE APPROACH. II. ELLIPTICAL ORBITS

    International Nuclear Information System (INIS)

    Cuntz, M.

    2015-01-01

    In the first paper of this series, a comprehensive approach has been provided for the study of S-type and P-type habitable regions in stellar binary systems, which was, however, restricted to circular orbits of the stellar components. Fortunately, a modest modification of the method also allows for the consideration of elliptical orbits, which of course entails a much broader range of applicability. This augmented method is presented here, and numerous applications are conveyed. In alignment with Paper I, the selected approach considers a variety of aspects, which comprise the consideration of a joint constraint including orbital stability and a habitable region for a possible system planet through the stellar radiative energy fluxes ( r adiative habitable zone ; RHZ). The devised method is based on a combined formalism for the assessment of both S-type and P-type habitability; in particular, mathematical criteria are deduced for which kinds of systems S-type and P-type habitable zones are realized. If the RHZs are truncated by the additional constraint of orbital stability, the notation of ST-type and PT-type habitability applies. In comparison to the circular case, it is found that in systems of higher eccentricity, the range of the RHZs is significantly reduced. Moreover, for a considerable number of models, the orbital stability constraint also reduces the range of S-type and P-type habitability. Nonetheless, S-, P-, ST-, and PT-type habitability is identified for a considerable set of system parameters. The method as presented is utilized for BinHab, an online code available at The University of Texas at Arlington

  15. Continuous Quality Improvement and Comprehensive Primary Health Care: A Systems Framework to Improve Service Quality and Health Outcomes

    Science.gov (United States)

    McCalman, Janya; Bailie, Ross; Bainbridge, Roxanne; McPhail-Bell, Karen; Percival, Nikki; Askew, Deborah; Fagan, Ruth; Tsey, Komla

    2018-01-01

    Continuous quality improvement (CQI) processes for improving clinical care and health outcomes have been implemented by primary health-care services, with resultant health-care impacts. But only 10–20% of gain in health outcomes is contributed by health-care services; a much larger share is determined by social and cultural factors. This perspective paper argues that health care and health outcomes can be enhanced through applying CQI as a systems approach to comprehensive primary health care. Referring to the Aboriginal and Torres Strait Islander Australian context as an example, the authors provide a systems framework that includes strategies and conditions to facilitate evidence-based and local decision making by primary health-care services. The framework describes the integration of CQI vertically to improve linkages with governments and community members and horizontally with other sectors to influence the social and cultural determinants of health. Further, government and primary health-care service investment is required to support and extend integration and evaluation of CQI efforts vertically and horizontally. PMID:29623271

  16. Continuous Quality Improvement and Comprehensive Primary Health Care: A Systems Framework to Improve Service Quality and Health Outcomes

    Directory of Open Access Journals (Sweden)

    Janya McCalman

    2018-03-01

    Full Text Available Continuous quality improvement (CQI processes for improving clinical care and health outcomes have been implemented by primary health-care services, with resultant health-care impacts. But only 10–20% of gain in health outcomes is contributed by health-care services; a much larger share is determined by social and cultural factors. This perspective paper argues that health care and health outcomes can be enhanced through applying CQI as a systems approach to comprehensive primary health care. Referring to the Aboriginal and Torres Strait Islander Australian context as an example, the authors provide a systems framework that includes strategies and conditions to facilitate evidence-based and local decision making by primary health-care services. The framework describes the integration of CQI vertically to improve linkages with governments and community members and horizontally with other sectors to influence the social and cultural determinants of health. Further, government and primary health-care service investment is required to support and extend integration and evaluation of CQI efforts vertically and horizontally.

  17. Continuous Quality Improvement and Comprehensive Primary Health Care: A Systems Framework to Improve Service Quality and Health Outcomes.

    Science.gov (United States)

    McCalman, Janya; Bailie, Ross; Bainbridge, Roxanne; McPhail-Bell, Karen; Percival, Nikki; Askew, Deborah; Fagan, Ruth; Tsey, Komla

    2018-01-01

    Continuous quality improvement (CQI) processes for improving clinical care and health outcomes have been implemented by primary health-care services, with resultant health-care impacts. But only 10-20% of gain in health outcomes is contributed by health-care services; a much larger share is determined by social and cultural factors. This perspective paper argues that health care and health outcomes can be enhanced through applying CQI as a systems approach to comprehensive primary health care. Referring to the Aboriginal and Torres Strait Islander Australian context as an example, the authors provide a systems framework that includes strategies and conditions to facilitate evidence-based and local decision making by primary health-care services. The framework describes the integration of CQI vertically to improve linkages with governments and community members and horizontally with other sectors to influence the social and cultural determinants of health. Further, government and primary health-care service investment is required to support and extend integration and evaluation of CQI efforts vertically and horizontally.

  18. Music intervention as system: Reversing hyper systemizing in Autism Spectrum Disorders to the comprehension of music as intervention

    NARCIS (Netherlands)

    Jaschke, A.C.; Scherder, E.J.A.

    2013-01-01

    his paper seeks to combine the notion of the empathising-systemising (E-S) theory and the resulting twist from the executive dysfunction theory in autism spectrum conditions in light of music intervention as system. To achieve these points it will be important to re-visit, nonetheless briefly, the

  19. Music intervention as system: reversing Hyper Systemizing in Autism Spectrum Disorders to the comprehension of music as intervention

    NARCIS (Netherlands)

    Jaschke, A.C.

    2014-01-01

    This paper seeks to combine the notion of the Empathising-Systemising (E-S) theory and the resulting twist from the executive dysfunction theory in autism spectrum conditions (ASC) in light of music intervention as system.To achieve these points it will be important to re-visit, nonetheless briefly,

  20. SITE COMPREHENSIVE LISTING (CERCLIS) (Superfund)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) (Superfund) Public Access Database contains a selected set of...

  1. Spectrum of physics comprehension

    International Nuclear Information System (INIS)

    Blasiak, W; Godlewska, M; Rosiek, R; Wcislo, D

    2012-01-01

    The paper presents the results of research on the relationship between self-assessed comprehension of physics lectures and final grades of junior high school students (aged 13-15), high school students (aged 16-18) and physics students at the Pedagogical University of Cracow, Poland (aged 21). Students' declared level of comprehension was measured during a physics lecture on a prearranged scale of 1-10 with the use of a personal response system designed for the purpose of this experiment. Through the use of this tool, we obtained about 2000 computer records of students' declared comprehension of a 45 min lecture, which we named ‘the spectrum of comprehension’. In this paper, we present and analyse the correlation between students' declared comprehension of the content presented in the lecture and their final learning results. (paper)

  2. Report on the comprehensive investigational research (at-home welfare apparatus system); Sogo chosa kenkyu (zaitaku fukushi kiki system) hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    An investigational study was conducted on the research and development of an at-home welfare apparatus system. In this study, a stay experiment was carried out on whether aged or handicapped people can easily live in welfare houses into which at-home welfare apparatus was integrated, using high-tech at-home nursing apparatus systems (welfare techno house: WTH) which were installed at seven places in Japan based on `the development of a system supporting independent excretion.` In addition, the following were conducted: experiments on at-home welfare apparatus in terms of the evaluation of performance/operability/safety, physical physiology reactions, nursing burden/estimate of independence, two-way communication, examination of housing environments, etc. In WTH Chofu, a test on evaluating welfare apparatus was conducted by people with limbs paralysis and healthy case workers. In WTH Sapporo, by a working group studying biological information, examinations were made on the situation of standing up of healthy adults, old people and people with paralysis of one side of the body from various types of chairs, beds, wheel chairs, portable toilets and sitting down on them. An examination was also made on harmony with psychological function and physically adaptable function by a working group studying at-home nursing apparatus. 75 figs., 15 tabs.

  3. Report on a comprehensive research study (home welfare apparatus system - interface); Sogo chosa kenkyu (zaitaku fukushi kiki system - interface) hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    In the light of the increasing role of welfare at home with the advance of the aging society, the paper conducted an investigational study on the R and D of the home welfare apparatus system - interface. In the study, making the most of the leading home care apparatus systems (welfare technohouses) installed at seven places in the country, the paper carried out a stay experiment on how the life is in the welfare house into which home welfare apparatus is integrated, and an experiment to assess biological data on aged people. Especially as to the support apparatus used for smooth life motions in houses such as movement, excretion and bathing, examined were the linkage with house bodies, care apparatus used, mutual interface with welfare apparatus, etc. By the experiments to assess these home welfare apparatus, an analytical study was conducted on the points to be improved in welfare apparatus and housing equipment, and at the same time on the course of the research/development. Concerning a system for the research study, a research promotion committee was established in Technology Research Association of Medical and Welfare Apparatus, the members of which are learned persons from the industrial circle, the government and universities. 111 figs., 36 tabs.

  4. Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis--A Comprehensive Review and Guide to Therapy. I. Systemic Disease.

    Science.gov (United States)

    Kohanim, Sahar; Palioura, Sotiria; Saeed, Hajirah N; Akpek, Esen K; Amescua, Guillermo; Basu, Sayan; Blomquist, Preston H; Bouchard, Charles S; Dart, John K; Gai, Xiaowu; Gomes, José A P; Gregory, Darren G; Iyer, Geetha; Jacobs, Deborah S; Johnson, Anthony J; Kinoshita, Shigeru; Mantagos, Iason S; Mehta, Jodhbir S; Perez, Victor L; Pflugfelder, Stephen C; Sangwan, Virender S; Sippel, Kimberly C; Sotozono, Chie; Srinivasan, Bhaskar; Tan, Donald T H; Tandon, Radhika; Tseng, Scheffer C G; Ueta, Mayumi; Chodosh, James

    2016-01-01

    The intent of this review is to comprehensively appraise the state of the art with regard to Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), with particular attention to the ocular surface complications and their management. SJS and TEN represent two ends of a spectrum of immune-mediated, dermatobullous disease, characterized in the acute phase by a febrile illness followed by skin and mucous membrane necrosis and detachment. The widespread keratinocyte death seen in SJS/TEN is rapid and irreversible, and even with early and aggressive intervention, morbidity is severe and mortality not uncommon. We have divided this review into two parts. Part I summarizes the epidemiology and immunopathogenesis of SJS/TEN and discusses systemic therapy and its possible benefits. We hope this review will help the ophthalmologist better understand the mechanisms of disease in SJS/TEN and enhance their care of patients with this complex and often debilitating disease. Part II (April 2016 issue) will focus on ophthalmic manifestations. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. A comprehensive system for dosimetric commissioning and Monte Carlo validation for the small animal radiation research platform.

    Science.gov (United States)

    Tryggestad, E; Armour, M; Iordachita, I; Verhaegen, F; Wong, J W

    2009-09-07

    Our group has constructed the small animal radiation research platform (SARRP) for delivering focal, kilo-voltage radiation to targets in small animals under robotic control using cone-beam CT guidance. The present work was undertaken to support the SARRP's treatment planning capabilities. We have devised a comprehensive system for characterizing the radiation dosimetry in water for the SARRP and have developed a Monte Carlo dose engine with the intent of reproducing these measured results. We find that the SARRP provides sufficient therapeutic dose rates ranging from 102 to 228 cGy min(-1) at 1 cm depth for the available set of high-precision beams ranging from 0.5 to 5 mm in size. In terms of depth-dose, the mean of the absolute percentage differences between the Monte Carlo calculations and measurement is 3.4% over the full range of sampled depths spanning 0.5-7.2 cm for the 3 and 5 mm beams. The measured and computed profiles for these beams agree well overall; of note, good agreement is observed in the profile tails. Especially for the smallest 0.5 and 1 mm beams, including a more realistic description of the effective x-ray source into the Monte Carlo model may be important.

  6. A comprehensive system for dosimetric commissioning and Monte Carlo validation for the small animal radiation research platform

    Energy Technology Data Exchange (ETDEWEB)

    Tryggestad, E; Armour, M; Wong, J W [Deptartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD (United States); Iordachita, I [Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD (United States); Verhaegen, F [Department of Radiation Oncology (MAASTRO Physics), GROW School, Maastricht University Medical Center, Maastricht (Netherlands)

    2009-09-07

    Our group has constructed the small animal radiation research platform (SARRP) for delivering focal, kilo-voltage radiation to targets in small animals under robotic control using cone-beam CT guidance. The present work was undertaken to support the SARRP's treatment planning capabilities. We have devised a comprehensive system for characterizing the radiation dosimetry in water for the SARRP and have developed a Monte Carlo dose engine with the intent of reproducing these measured results. We find that the SARRP provides sufficient therapeutic dose rates ranging from 102 to 228 cGy min{sup -1} at 1 cm depth for the available set of high-precision beams ranging from 0.5 to 5 mm in size. In terms of depth-dose, the mean of the absolute percentage differences between the Monte Carlo calculations and measurement is 3.4% over the full range of sampled depths spanning 0.5-7.2 cm for the 3 and 5 mm beams. The measured and computed profiles for these beams agree well overall; of note, good agreement is observed in the profile tails. Especially for the smallest 0.5 and 1 mm beams, including a more realistic description of the effective x-ray source into the Monte Carlo model may be important.

  7. A comprehensive sediment dynamics study of a major mud belt system on the inner shelf along an energetic coast.

    Science.gov (United States)

    Liu, James T; Hsu, Ray T; Yang, Rick J; Wang, Ya Ping; Wu, Hui; Du, Xiaoqin; Li, Anchun; Chien, Steven C; Lee, Jay; Yang, Shouye; Zhu, Jianrong; Su, Chih-Chieh; Chang, Yi; Huh, Chih-An

    2018-03-09

    Globally mud areas on continental shelves are conduits for the dispersal of fluvial-sourced sediment. We address fundamental issues in sediment dynamics focusing on how mud is retained on the seabed on shallow inner shelves and what are the sources of mud. Through a process-based comprehensive study that integrates dynamics, provenance, and sedimentology, here we show that the key mechanism to keep mud on the seabed is the water-column stratification that forms a dynamic barrier in the vertical that restricts the upward mixing of suspended sediment. We studied the 1000 km-long mud belt that extends from the mouth of the Changjiang (Yangtze) River along the coast of Zhejiang and Fujian Provinces of China and ends on the west coast of Taiwan. This mud belt system is dynamically attached to the fluvial sources, of which the Changjiang River is the primary source. Winter is the constructive phase when active deposition takes place of fine-grained sediment carried mainly by the Changjiang plume driven by Zhe-Min Coastal Currents southwestward along the coast.

  8. Report on a comprehensive research study (home welfare apparatus system - lifestyle); Sogo chosa kenkyu (zaitaku fukushi kiki system - lifestyle) hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    An investigational study was conducted on evacuation of aged people at disaster, life maintenance, and welfare apparatus which is applicable to the future change of life style and its harmony with the living environment. In the study of care apparatus, reported were the apparatus operational interface using the indoor environmental control simulation system, safety on moving/transfer equipment, experiment on opening/closing power of sliding doors, study of electric-driven wheel chairs, study of the sitting pressure of various wheel chairs, etc. In relation to the living environment, the paper reported planning of houses introducing care apparatus, assessment of system kitchen, disaster prevention measures for aged/handicapped people, study on performance of the combined use in the living environment, assessment of drops in floor level in the living space, etc. Also reported were assessment on the living environmental control state of serious paralyzers of the limbs, study of a network to support care at home, etc. 48 refs., 117 figs., 29 tabs.

  9. Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics

    Directory of Open Access Journals (Sweden)

    Zhang Dapeng

    2012-06-01

    polymorphic toxin systems predicts the presence of novel trafficking-related components, and also the organizational logic that allows toxin diversification through recombination. Domain architecture and protein-length analysis revealed that these toxins might be deployed as secreted factors, through directed injection, or via inter-cellular contact facilitated by filamentous structures formed by RHS/YD, filamentous hemagglutinin and other repeats. Phyletic pattern and life-style analysis indicate that polymorphic toxins and polyimmunity loci participate in cooperative behavior and facultative ‘cheating’ in several ecosystems such as the human oral cavity and soil. Multiple domains from these systems have also been repeatedly transferred to eukaryotes and their viruses, such as the nucleo-cytoplasmic large DNA viruses. Conclusions Along with a comprehensive inventory of toxins and immunity proteins, we present several testable predictions regarding active sites and catalytic mechanisms of toxins, their processing and trafficking and their role in intra-specific and inter-specific interactions between bacteria. These systems provide insights regarding the emergence of key systems at different points in eukaryotic evolution, such as ADP ribosylation, interaction of myosin VI with cargo proteins, mediation of apoptosis, hyphal heteroincompatibility, hedgehog signaling, arthropod toxins, cell-cell interaction molecules like teneurins and different signaling messengers. Reviewers This article was reviewed by AM, FE and IZ.

  10. [Introduction of computerized anesthesia-recording systems and construction of comprehensive medical information network for patients undergoing surgery in the University of Tokyo Hospital].

    Science.gov (United States)

    Kitamura, Takayuki; Hoshimoto, Hiroyuki; Yamada, Yoshitsugu

    2009-10-01

    The computerized anesthesia-recording systems are expensive and the introduction of the systems takes time and requires huge effort. Generally speaking, the efficacy of the computerized anesthesia-recording systems on the anesthetic managements is focused on the ability to automatically input data from the monitors to the anesthetic records, and tends to be underestimated. However, once the computerized anesthesia-recording systems are integrated into the medical information network, several features, which definitely contribute to improve the quality of the anesthetic management, can be developed; for example, to prevent misidentification of patients, to prevent mistakes related to blood transfusion, and to protect patients' personal information. Here we describe our experiences of the introduction of the computerized anesthesia-recording systems and the construction of the comprehensive medical information network for patients undergoing surgery in The University of Tokyo Hospital. We also discuss possible efficacy of the comprehensive medical information network for patients during surgery under anesthetic managements.

  11. Comprehensive evaluation of electronic medical record system use and user satisfaction at five low-resource setting hospitals in ethiopia.

    Science.gov (United States)

    Tilahun, Binyam; Fritz, Fleur

    2015-05-25

    Electronic medical record (EMR) systems are increasingly being implemented in hospitals of developing countries to improve patient care and clinical service. However, only limited evaluation studies are available concerning the level of adoption and determinant factors of success in those settings. The objective of this study was to assess the usage pattern, user satisfaction level, and determinants of health professional's satisfaction towards a comprehensive EMR system implemented in Ethiopia where parallel documentation using the EMR and the paper-based medical records is in practice. A quantitative, cross-sectional study design was used to assess the usage pattern, user satisfaction level, and determinant factors of an EMR system implemented in Ethiopia based on the DeLone and McLean model of information system success. Descriptive statistical methods were applied to analyze the data and a binary logistic regression model was used to identify determinant factors. Health professionals (N=422) from five hospitals were approached and 406 responded to the survey (96.2% response rate). Out of the respondents, 76.1% (309/406) started to use the system immediately after implementation and user training, but only 31.7% (98/309) of the professionals reported using the EMR during the study (after 3 years of implementation). Of the 12 core EMR functions, 3 were never used by most respondents, and they were also unaware of 4 of the core EMR functions. It was found that 61.4% (190/309) of the health professionals reported over all dissatisfaction with the EMR (median=4, interquartile range (IQR)=1) on a 5-level Likert scale. Physicians were more dissatisfied (median=5, IQR=1) when compared to nurses (median=4, IQR=1) and the health management information system (HMIS) staff (median=2, IQR=1). Of all the participants, 64.4% (199/309) believed that the EMR had no positive impact on the quality of care. The participants indicated an agreement with the system and information

  12. Functional Movement Screen (FMS - kompleksowy system oceny funkcjonalnej pacjenta = Functional Movement Screen (FMS - a comprehensive system for the functional evaluation of the patient

    Directory of Open Access Journals (Sweden)

    Bartosz Kochański

    2015-04-01

    4 Wydział Kultury Fizycznej, Zdrowia i Turystyki, Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Polska   Streszczenie   System oceny funkcjonalnej - Functional Movement Screen (FMS został stworzony przez Graya Cooka oraz Lee Burtona w 1995 roku. FMS jest koncepcją, która umożliwia kompleksową analizę jakości podstawowych wzorców ruchowych, ocenę ryzyka kontuzji oraz stwierdzenie istnienia ograniczeń i asymetrii. Test FMS złożony jest z 7 prób (głęboki przysiad, przeniesienie kończyny dolnej nad płotkiem, przysiad w wykroku, ruchomość obręczy barkowej, aktywne uniesienie wyprostowanej kończyny dolnej, ugięcie ramion w podporze, stabilność rotacyjna tułowia. W pracy zaprezentowano test Functional Movement Screen, jako kompleksowy system oceny funkcjonalnej pacjenta.   Słowa kluczowe: Functional Movement Screen, FMS, ocena funkcjonalna, rehabilitacja.   Abstract   Functional Movement Screen (FMS was created by Gray Cook and Lee Burton in 1995. FMS is a concept that allows comprehensive analysis of the quality of basic movement patterns, risk assessment and finding of injury to the limitations and asymmetries. FMS test consists of 7 samples (deep squat, hurdle step, in-line lunge, shoulder mobility, active straight leg raise, trunk stability push up, rotational stability. The paper presents the Functional Movement Screen test, as a comprehensive system of functional assessment of the patient.   Key words: Functional Movement Screen, FMS, functional assessment, rehabilitation.

  13. A comprehensive complex systems approach to the study and analysis of mammalian cell cycle control system in the presence of DNA damage stress.

    Science.gov (United States)

    Abroudi, Ali; Samarasinghe, Sandhya; Kulasiri, Don

    2017-09-21

    Not many models of mammalian cell cycle system exist due to its complexity. Some models are too complex and hard to understand, while some others are too simple and not comprehensive enough. Moreover, some essential aspects, such as the response of G1-S and G2-M checkpoints to DNA damage as well as the growth factor signalling, have not been investigated from a systems point of view in current mammalian cell cycle models. To address these issues, we bring a holistic perspective to cell cycle by mathematically modelling it as a complex system consisting of important sub-systems that interact with each other. This retains the functionality of the system and provides a clearer interpretation to the processes within it while reducing the complexity in comprehending these processes. To achieve this, we first update a published ODE mathematical model of cell cycle with current knowledge. Then the part of the mathematical model relevant to each sub-system is shown separately in conjunction with a diagram of the sub-system as part of this representation. The model sub-systems are Growth Factor, DNA damage, G1-S, and G2-M checkpoint signalling. To further simplify the model and better explore the function of sub-systems, they are further divided into modules. Here we also add important new modules of: chk-related rapid cell cycle arrest, p53 modules expanded to seamlessly integrate with the rapid arrest module, Tyrosine phosphatase modules that activate Cyc_Cdk complexes and play a crucial role in rapid and delay arrest at both G1-S and G2-M, Tyrosine Kinase module that is important for inactivating nuclear transport of CycB_cdk1 through Wee1 to resist M phase entry, Plk1-Related module that is crucial in activating Tyrosine phosphatases and inactivating Tyrosine kinase, and APC-Related module to show steps in CycB degradation. This multi-level systems approach incorporating all known aspects of cell cycle allowed us to (i) study, through dynamic simulation of an ODE model

  14. Development of RODOS (Real-Time, On-Line Decision Support System), a comprehensive decision support system for nuclear emergencies in Europe - an overview

    International Nuclear Information System (INIS)

    Ehrhardt, J.; Paesler-Sauer, J.; Schuele, O.

    1993-01-01

    Within its Radiation Protection Research Programme, the Commission of the European Communities has embarked on a major project aiming at the development of an integrated and comprehensive real-time on-line decision support system (RODOS) for nuclear emergencies in Europe, applicable for the vicinity of the release and the early phase up to far distant areas and the later stages of an accident. At present, the project is organised as a joint venture of some 18 European institutes closely cooperating with several Russian and Ukrainian laboratories. The main purpose of the project is to provide the methodological basis, develop models and data and install the hardware and software framework of RODOS. The paper describes the key features, the overall design and the software structure broadly accepted by the contractors. The paper sketches the present status of RODOS and gives an overview of the important tasks of R and D work for the next project phases. (author)

  15. Health Information Technology Evaluation Framework (HITREF) Comprehensiveness as Assessed in Electronic Point-of-Care Documentation Systems Evaluations.

    Science.gov (United States)

    Sockolow, Paulina S; Bowles, Kathryn H; Rogers, Michelle

    2015-01-01

    We assessed the Health Information Technology (HIT) Reference-based Evaluation Framework (HITREF) comprehensiveness in two HIT evaluations in settings different from that in which the HITREF was developed. Clinician satisfaction themes that emerged from clinician interviews in the home care and the hospital studies were compared to the framework components. Across both studies, respondents commented on 12 of the 20 HITREF components within 5 of the 6 HITREF concepts. No new components emerged that were missing from the HITREF providing evidence that the HITREF is a comprehensive framework. HITREF use in a range of HIT evaluations by researchers new to the HITREF demonstrates that it can be used as intended. Therefore, we continue to recommend the HITREF as a comprehensive, research-based HIT evaluation framework to increase the capacity of informatics evaluators' use of best practice and evidence-based practice to support the credibility of their findings for fulfilling the purpose of program evaluation.

  16. Towards the Development of a Comprehensive Pedagogical Framework for Pronunciation Training Based on Adapted Automatic Speech Recognition Systems

    Science.gov (United States)

    Ali, Saandia

    2016-01-01

    This paper reports on the early stages of a locally funded research and development project taking place at Rennes 2 university. It aims at developing a comprehensive pedagogical framework for pronunciation training for adult learners of English. This framework will combine a direct approach to pronunciation training (face-to-face teaching) with…

  17. Early & Often: Designing a Comprehensive System of Financial Aid Information. A Report of the Advisory Committee on Student Financial Assistance

    Science.gov (United States)

    Advisory Committee on Student Financial Assistance, 2008

    2008-01-01

    Students and parents need ample time and accurate information to prepare for the financial burden of a college education--those who lack this knowledge base face a significant access barrier to higher education. This problem can be countered by the delivery of comprehensive, integrated financial aid information, an approach identified by the…

  18. A proposal for a comprehensive risk scoring system for predicting postoperative complications in octogenarian patients with medically operable lung cancer: JACS1303.

    Science.gov (United States)

    Saji, Hisashi; Ueno, Takahiko; Nakamura, Hiroshige; Okumura, Norihito; Tsuchida, Masanori; Sonobe, Makoto; Miyazaki, Takuro; Aokage, Keiju; Nakao, Masayuki; Haruki, Tomohiro; Ito, Hiroyuki; Kataoka, Kazuhiko; Okabe, Kazunori; Tomizawa, Kenji; Yoshimoto, Kentaro; Horio, Hirotoshi; Sugio, Kenji; Ode, Yasuhisa; Takao, Motoshi; Okada, Morihito; Chida, Masayuki

    2018-04-01

    Although some retrospective studies have reported clinicopathological scoring systems for predicting postoperative complications and survival outcomes for elderly lung cancer patients, optimized scoring systems remain controversial. The Japanese Association for Chest Surgery (JACS) conducted a nationwide multicentre prospective cohort and enrolled a total of 1019 octogenarians with medically operable lung cancer. Details of the clinical factors, comorbidities and comprehensive geriatric assessment were recorded for 895 patients to develop a comprehensive risk scoring (RS) system capable of predicting severe complications. Operative (30 days) and hospital mortality rates were 1.0% and 1.6%, respectively. Complications were observed in 308 (34%) patients, of whom 81 (8.4%) had Grade 3-4 severe complications. Pneumonia was the most common severe complication, observed in 27 (3.0%) patients. Five predictive factors, gender, comprehensive geriatric assessment75: memory and Simplified Comorbidity Score (SCS): diabetes mellitus, albumin and percentage vital capacity, were identified as independent predictive factors for severe postoperative complications (odds ratio = 2.73, 1.86, 1.54, 1.66 and 1.61, respectively) through univariate and multivariate analyses. A 5-fold cross-validation was performed as an internal validation to reconfirm these 5 predictive factors (average area under the curve 0.70). We developed a simplified RS system as follows: RS = 3 (gender: male) + 2 (comprehensive geriatric assessment 75: memory: yes) + 2 (albumin: <3.8 ng/ml) + 1 (percentage vital capacity: ≤90) + 1 (SCS: diabetes mellitus: yes). The current series shows that octogenarians can be successfully treated for lung cancer with surgical resection with an acceptable rate of severe complications and mortality. We propose a simplified RS system to predict severe complications in octogenarian patients with medically operative lung cancer. JACS1303 (UMIN000016756).

  19. The Environmental Advisory Service (EASe): a decision support system for comprehensive screening of local land-use development proposals and comparative evaluation of proposed land-use plans

    OpenAIRE

    K P White; A P Sage; F A Rodammer; C T Peters

    1985-01-01

    The Environmental Advisory Service (EASe) is a decision support system which can provide assistance to local planning agencies in selecting land-development alternatives or in formulating land-use plans. EASe offers a comprehensive and consistent procedure for rating either a development proposal or a proposed plan. This procedure is based upon qualitative assessments of the impact of developments or plans on the natural environment, zoning and land use. public and private services, transport...

  20. Integrating indigenous knowledge systems (IKS) in improving rural accessibility and mobility (in support of the comprehensive rural development programme in South Africa)

    CSIR Research Space (South Africa)

    Nhemachena, C

    2011-07-01

    Full Text Available INDIGENOUS KNOWLEDGE SYSTEMS (IKS) IN IMPROVING RURAL ACCESSIBILITY AND MOBILITY (IN SUPPORT OF THE COMPREHENSIVE RURAL DEVELOPMENT PROGRAMME IN SOUTH AFRICA) CHARLES NHEMACHENA1, JAMES CHAKWIZIRA2, SIPHO DUBE1, GOODHOPE MAPONYA1, REMINA RASHOPOLA3... of Environmental Sciences, Private Bag X5050, Thohoyandou, 0950 3 Department of Rural Development and Land Reform, PO Box X833, Pretoria 0001 ABSTRACT This study discusses opportunities and challenges for integrating local knowledge in improving...

  1. Comprehensive Analysis of the Geoeffective Solar Event of 21 June 2015: Effects on the Magnetosphere, Plasmasphere, and Ionosphere Systems

    Science.gov (United States)

    Piersanti, Mirko; Alberti, Tommaso; Bemporad, Alessandro; Berrilli, Francesco; Bruno, Roberto; Capparelli, Vincenzo; Carbone, Vincenzo; Cesaroni, Claudio; Consolini, Giuseppe; Cristaldi, Alice; Del Corpo, Alfredo; Del Moro, Dario; Di Matteo, Simone; Ermolli, Ilaria; Fineschi, Silvano; Giannattasio, Fabio; Giorgi, Fabrizio; Giovannelli, Luca; Guglielmino, Salvatore Luigi; Laurenza, Monica; Lepreti, Fabio; Marcucci, Maria Federica; Martucci, Matteo; Mergè, Matteo; Pezzopane, Michael; Pietropaolo, Ermanno; Romano, Paolo; Sparvoli, Roberta; Spogli, Luca; Stangalini, Marco; Vecchio, Antonio; Vellante, Massimo; Villante, Umberto; Zuccarello, Francesca; Heilig, Balázs; Reda, Jan; Lichtenberger, János

    2017-11-01

    A full-halo coronal mass ejection (CME) left the Sun on 21 June 2015 from active region (AR) NOAA 12371. It encountered Earth on 22 June 2015 and generated a strong geomagnetic storm whose minimum Dst value was -204 nT. The CME was associated with an M2-class flare observed at 01:42 UT, located near disk center (N12 E16). Using satellite data from solar, heliospheric, and magnetospheric missions and ground-based instruments, we performed a comprehensive Sun-to-Earth analysis. In particular, we analyzed the active region evolution using ground-based and satellite instruments (Big Bear Solar Observatory (BBSO), Interface Region Imaging Spectrograph (IRIS), Hinode, Atmospheric Imaging Assembly (AIA) onboard the Solar Dynamics Observatory (SDO), Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI), covering Hα, EUV, UV, and X-ray data); the AR magnetograms, using data from SDO/ Helioseismic and Magnetic Imager (HMI); the high-energy particle data, using the Payload for Antimatter Matter Exploration and Light-nuclei Astrophysics (PAMELA) instrument; and the Rome neutron monitor measurements to assess the effects of the interplanetary perturbation on cosmic-ray intensity. We also evaluated the 1 - 8 Å soft X-ray data and the {˜} 1 MHz type III radio burst time-integrated intensity (or fluence) of the flare in order to predict the associated solar energetic particle (SEP) event using the model developed by Laurenza et al. ( Space Weather 7(4), 2009). In addition, using ground-based observations from lower to higher latitudes ( International Real-time Magnetic Observatory Network (INTERMAGNET) and European Quasi-Meridional Magnetometer Array (EMMA)), we reconstructed the ionospheric current system associated with the geomagnetic sudden impulse (SI). Furthermore, Super Dual Auroral Radar Network (SuperDARN) measurements were used to image the global ionospheric polar convection during the SI and during the principal phases of the geomagnetic storm. In addition

  2. A HIGH-LEVEL PYTHON INTERFACE TO THE FERMILAB ACNET CONTROL SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    Piot, P. [Fermilab; Halavanau, A. [Fermilab

    2016-10-19

    This paper discusses the implementation of a python- based high-level interface to the Fermilab acnet control system. The interface has been successfully employed during the commissioning of the Fermilab Accelerator Science & Technology (FAST) facility. Specifically, we present examples of applications at FAST which include the interfacing of the elegant program to assist lattice matching, an automated emittance measurement via the quadrupole-scan method and tranverse transport matrix measurement of a superconducting RF cavity.

  3. Comprehensive Logistics

    CERN Document Server

    Gudehus, Timm

    2012-01-01

    Modern logistics comprises operative logistics, analytical logistics and management of logistic networks. Central task of operative logistics is the efficient supply of required goods at the right place within the right time. Tasks of analytical logistics are designing optimal networks and systems, developing strategies for planning, scheduling and operation, and organizing efficient order and performance processes. Logistic management plans, implements and operates logistic networks and schedules orders, stocks and resources. This reference-book offers a unique survey of modern logistics. It contains proven strategies, rules and tools for the solution of a multitude of logistic problems. The analytically derived algorithms and formulas can be used for the computer-based planning of logistic systems and for the dynamic scheduling of orders and resources in supply networks. They enable significant improvements of performance, quality and costs. Their application is demonstrated by several examples from industr...

  4. Microprocessors & their operating systems a comprehensive guide to 8, 16 & 32 bit hardware, assembly language & computer architecture

    CERN Document Server

    Holland, R C

    1989-01-01

    Provides a comprehensive guide to all of the major microprocessor families (8, 16 and 32 bit). The hardware aspects and software implications are described, giving the reader an overall understanding of microcomputer architectures. The internal processor operation of each microprocessor device is presented, followed by descriptions of the instruction set and applications for the device. Software considerations are expanded with descriptions and examples of the main high level programming languages (BASIC, Pascal and C). The book also includes detailed descriptions of the three main operatin

  5. The clinical value of lncRNA NEAT1 in digestive system malignancies: A comprehensive investigation based on 57 microarray and RNA-seq datasets.

    Science.gov (United States)

    Xiong, Dan-Dan; Feng, Zhen-Bo; Cen, Wei-Luan; Zeng, Jing-Jing; Liang, Lu; Tang, Rui-Xue; Gan, Xiao-Ning; Liang, Hai-Wei; Li, Zu-Yun; Chen, Gang; Luo, Dian-Zhong

    2017-03-14

    This comprehensive investigation was performed to evaluate the expression level and potential clinical value of NEAT1 in digestive system malignancies. A total of 57 lncRNA datasets of microarray or RNA-seq and 5 publications were included. The pooled standard mean deviation (SMD) indicated that NEAT1 was down-regulated in esophageal carcinoma (ESCA, SMD = -0.35, 95% CI: -0.5~-0.20, P digestive system malignancies (HR: 1.50, 95% CI: 1.28-1.76, P digestive system cancers and could be a potential diagnostic and prognostic biomarker in patients with digestive system carcinomas. Further and stricter studies with a larger number of cases are necessary to strengthen our conclusions.

  6. Comprehensive safety analysis code system for nuclear fusion reactors II: Thermal analysis during plasma disruptions for international thermonuclear experimental reactor

    International Nuclear Information System (INIS)

    Honda, T.; Maki, K.; Okazaki, T.

    1994-01-01

    Thermal characteristics of a fusion reactor [International Thermonuclear Experimental Reactor (ITER) Conceptual Design Activity] during plasma disruptions have been analyzed by using a comprehensive safety analysis code for nuclear fusion reactors. The erosion depth due to disruptions for the armor of the first wall depends on the current quench time of disruptions occurring in normal operation. If it is possible to extend the time up to ∼50 ms, the erosion depth is considerably reduced. On the other hand, the erosion depth of the divertor is ∼570 μm for only one disruption, which is determined only by the thermal flux during the thermal quench. This means that the divertor plate should be exchanged after about nine disruptions. Counter-measures are necessary for the divertor to relieve disruption influences. As other scenarios of disruptions, beta-limit disruptions and vertical displacement events were also investigated quantitatively. 13 refs., 5 figs

  7. Comprehensive Psychiatric Evaluation

    Science.gov (United States)

    ... Facts for Families Guide Facts for Families - Vietnamese Comprehensive Psychiatric Evaluation No. 52; Updated October 2017 Evaluation ... with serious emotional and behavioral problems need a comprehensive psychiatric evaluation. Comprehensive psychiatric evaluations usually require a ...

  8. Children's hypertext comprehension

    NARCIS (Netherlands)

    Segers, P.C.J.; Segers, E.; Broek, P. van den

    2017-01-01

    The present chapter gives an overview of the literature on hypertext comprehension, children's hypertext comprehension and individual variation therein, ending with a perspective for future research. Hypertext comprehension requires the reader to make bridging inferences between the different parts

  9. Zope based electronic operation log system - Zlog

    International Nuclear Information System (INIS)

    Yoshii, K.; Satoh, Y.; Kitabayashi, T.

    2004-01-01

    Since January 2004, the Zope based electronic operation logging system, named Zlog, has been running at the KEKB and AR accelerator facilities. Since Zope is the python based open source web application server software and python language is familiar for the members in the KEKB accelerator control group, we have developed the Zlog system rapidly. In this paper, we report the development history and the present status of Zlog system. Also we show some general plug-in components, called Zope products, have been useful for our Zlog development. (author)

  10. A Comprehensive Quality Evaluation System for Complex Herbal Medicine Using PacBio Sequencing, PCR-Denaturing Gradient Gel Electrophoresis, and Several Chemical Approaches

    Science.gov (United States)

    Zheng, Xiasheng; Zhang, Peng; Liao, Baosheng; Li, Jing; Liu, Xingyun; Shi, Yuhua; Cheng, Jinle; Lai, Zhitian; Xu, Jiang; Chen, Shilin

    2017-01-01

    Herbal medicine is a major component of complementary and alternative medicine, contributing significantly to the health of many people and communities. Quality control of herbal medicine is crucial to ensure that it is safe and sound for use. Here, we investigated a comprehensive quality evaluation system for a classic herbal medicine, Danggui Buxue Formula, by applying genetic-based and analytical chemistry approaches to authenticate and evaluate the quality of its samples. For authenticity, we successfully applied two novel technologies, third-generation sequencing and PCR-DGGE (denaturing gradient gel electrophoresis), to analyze the ingredient composition of the tested samples. For quality evaluation, we used high performance liquid chromatography assays to determine the content of chemical markers to help estimate the dosage relationship between its two raw materials, plant roots of Huangqi and Danggui. A series of surveys were then conducted against several exogenous contaminations, aiming to further access the efficacy and safety of the samples. In conclusion, the quality evaluation system demonstrated here can potentially address the authenticity, quality, and safety of herbal medicines, thus providing novel insight for enhancing their overall quality control. Highlight: We established a comprehensive quality evaluation system for herbal medicine, by combining two genetic-based approaches third-generation sequencing and DGGE (denaturing gradient gel electrophoresis) with analytical chemistry approaches to achieve the authentication and quality connotation of the samples. PMID:28955365

  11. A Comprehensive Quality Evaluation System for Complex Herbal Medicine Using PacBio Sequencing, PCR-Denaturing Gradient Gel Electrophoresis, and Several Chemical Approaches

    Directory of Open Access Journals (Sweden)

    Xiasheng Zheng

    2017-09-01

    Full Text Available Herbal medicine is a major component of complementary and alternative medicine, contributing significantly to the health of many people and communities. Quality control of herbal medicine is crucial to ensure that it is safe and sound for use. Here, we investigated a comprehensive quality evaluation system for a classic herbal medicine, Danggui Buxue Formula, by applying genetic-based and analytical chemistry approaches to authenticate and evaluate the quality of its samples. For authenticity, we successfully applied two novel technologies, third-generation sequencing and PCR-DGGE (denaturing gradient gel electrophoresis, to analyze the ingredient composition of the tested samples. For quality evaluation, we used high performance liquid chromatography assays to determine the content of chemical markers to help estimate the dosage relationship between its two raw materials, plant roots of Huangqi and Danggui. A series of surveys were then conducted against several exogenous contaminations, aiming to further access the efficacy and safety of the samples. In conclusion, the quality evaluation system demonstrated here can potentially address the authenticity, quality, and safety of herbal medicines, thus providing novel insight for enhancing their overall quality control.Highlight: We established a comprehensive quality evaluation system for herbal medicine, by combining two genetic-based approaches third-generation sequencing and DGGE (denaturing gradient gel electrophoresis with analytical chemistry approaches to achieve the authentication and quality connotation of the samples.

  12. A Comprehensive Quality Evaluation System for Complex Herbal Medicine Using PacBio Sequencing, PCR-Denaturing Gradient Gel Electrophoresis, and Several Chemical Approaches.

    Science.gov (United States)

    Zheng, Xiasheng; Zhang, Peng; Liao, Baosheng; Li, Jing; Liu, Xingyun; Shi, Yuhua; Cheng, Jinle; Lai, Zhitian; Xu, Jiang; Chen, Shilin

    2017-01-01

    Herbal medicine is a major component of complementary and alternative medicine, contributing significantly to the health of many people and communities. Quality control of herbal medicine is crucial to ensure that it is safe and sound for use. Here, we investigated a comprehensive quality evaluation system for a classic herbal medicine, Danggui Buxue Formula, by applying genetic-based and analytical chemistry approaches to authenticate and evaluate the quality of its samples. For authenticity, we successfully applied two novel technologies, third-generation sequencing and PCR-DGGE (denaturing gradient gel electrophoresis), to analyze the ingredient composition of the tested samples. For quality evaluation, we used high performance liquid chromatography assays to determine the content of chemical markers to help estimate the dosage relationship between its two raw materials, plant roots of Huangqi and Danggui. A series of surveys were then conducted against several exogenous contaminations, aiming to further access the efficacy and safety of the samples. In conclusion, the quality evaluation system demonstrated here can potentially address the authenticity, quality, and safety of herbal medicines, thus providing novel insight for enhancing their overall quality control. Highlight : We established a comprehensive quality evaluation system for herbal medicine, by combining two genetic-based approaches third-generation sequencing and DGGE (denaturing gradient gel electrophoresis) with analytical chemistry approaches to achieve the authentication and quality connotation of the samples.

  13. SU-E-T-11: A Cloud Based CT and LINAC QA Data Management System

    Energy Technology Data Exchange (ETDEWEB)

    Wiersma, R; Grelewicz, Z; Belcher, A; Liu, X [The University of Chicago, Chicago, IL (United States)

    2015-06-15

    Purpose: The current status quo of QA data management consists of a mixture of paper-based forms and spreadsheets for recording the results of daily, monthly, and yearly QA tests for both CT scanners and LINACs. Unfortunately, such systems suffer from a host of problems as, (1) records can be easily lost or destroyed, (2) data is difficult to access — one must physically hunt down records, (3) poor or no means of historical data analysis, and (4) no remote monitoring of machine performance off-site. To address these issues, a cloud based QA data management system was developed and implemented. Methods: A responsive tablet interface that optimizes clinic workflow with an easy-to-navigate interface accessible from any web browser was implemented in HTML/javascript/CSS to allow user mobility when entering QA data. Automated image QA was performed using a phantom QA kit developed in Python that is applicable to any phantom and is currently being used with the Gammex ACR, Las Vegas, Leeds, and Catphan phantoms for performing automated CT, MV, kV, and CBCT QAs, respectively. A Python based resource management system was used to distribute and manage intensive CPU tasks such as QA phantom image analysis or LaTeX-to-PDF QA report generation to independent process threads or different servers such that website performance is not affected. Results: To date the cloud QA system has performed approximately 185 QA procedures. Approximately 200 QA parameters are being actively tracked by the system on a monthly basis. Electronic access to historical QA parameter information was successful in proactively identifying a Linac CBCT scanner’s performance degradation. Conclusion: A fully comprehensive cloud based QA data management system was successfully implemented for the first time. Potential machine performance issues were proactively identified that would have been otherwise missed by a paper or spreadsheet based QA system.

  14. SU-E-T-11: A Cloud Based CT and LINAC QA Data Management System

    International Nuclear Information System (INIS)

    Wiersma, R; Grelewicz, Z; Belcher, A; Liu, X

    2015-01-01

    Purpose: The current status quo of QA data management consists of a mixture of paper-based forms and spreadsheets for recording the results of daily, monthly, and yearly QA tests for both CT scanners and LINACs. Unfortunately, such systems suffer from a host of problems as, (1) records can be easily lost or destroyed, (2) data is difficult to access — one must physically hunt down records, (3) poor or no means of historical data analysis, and (4) no remote monitoring of machine performance off-site. To address these issues, a cloud based QA data management system was developed and implemented. Methods: A responsive tablet interface that optimizes clinic workflow with an easy-to-navigate interface accessible from any web browser was implemented in HTML/javascript/CSS to allow user mobility when entering QA data. Automated image QA was performed using a phantom QA kit developed in Python that is applicable to any phantom and is currently being used with the Gammex ACR, Las Vegas, Leeds, and Catphan phantoms for performing automated CT, MV, kV, and CBCT QAs, respectively. A Python based resource management system was used to distribute and manage intensive CPU tasks such as QA phantom image analysis or LaTeX-to-PDF QA report generation to independent process threads or different servers such that website performance is not affected. Results: To date the cloud QA system has performed approximately 185 QA procedures. Approximately 200 QA parameters are being actively tracked by the system on a monthly basis. Electronic access to historical QA parameter information was successful in proactively identifying a Linac CBCT scanner’s performance degradation. Conclusion: A fully comprehensive cloud based QA data management system was successfully implemented for the first time. Potential machine performance issues were proactively identified that would have been otherwise missed by a paper or spreadsheet based QA system

  15. Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems.

    Science.gov (United States)

    Boué, Stéphanie; Talikka, Marja; Westra, Jurjen Willem; Hayes, William; Di Fabio, Anselmo; Park, Jennifer; Schlage, Walter K; Sewer, Alain; Fields, Brett; Ansari, Sam; Martin, Florian; Veljkovic, Emilija; Kenney, Renee; Peitsch, Manuel C; Hoeng, Julia

    2015-01-01

    With the wealth of publications and data available, powerful and transparent computational approaches are required to represent measured data and scientific knowledge in a computable and searchable format. We developed a set of biological network models, scripted in the Biological Expression Language, that reflect causal signaling pathways across a wide range of biological processes, including cell fate, cell stress, cell proliferation, inflammation, tissue repair and angiogenesis in the pulmonary and cardiovascular context. This comprehensive collection of networks is now freely available to the scientific community in a centralized web-based repository, the Causal Biological Network database, which is composed of over 120 manually curated and well annotated biological network models and can be accessed at http://causalbionet.com. The website accesses a MongoDB, which stores all versions of the networks as JSON objects and allows users to search for genes, proteins, biological processes, small molecules and keywords in the network descriptions to retrieve biological networks of interest. The content of the networks can be visualized and browsed. Nodes and edges can be filtered and all supporting evidence for the edges can be browsed and is linked to the original articles in PubMed. Moreover, networks may be downloaded for further visualization and evaluation. Database URL: http://causalbionet.com © The Author(s) 2015. Published by Oxford University Press.

  16. Whole-body MRI: comprehensive evaluation on a 48-channel 3T MRI system in less than 40 minutes. Preliminary results

    Directory of Open Access Journals (Sweden)

    Mateus de Andrade Hernandes

    2012-12-01

    Full Text Available OBJECTIVE: To evaluate a comprehensive MRI protocol that investigates for cancer, vascular disease, and degenerative/inflammatory disease from the head to the pelvis in less than 40 minutes on a new generation 48-channel 3T system. MATERIALS AND METHODS: All MR studies were performed on a 48-channel 3T MR scanner. A 20-channel head/neck coil, two 18-channel body arrays, and a 32-channel spine array were employed. A total of 4 healthy individuals were studied. The designed protocol included a combination of single-shot T2-weighted sequences, T1-weighted 3D gradient-echo pre- and post-gadolinium. All images were retrospectively evaluated by two radiologists independently for overall image quality. RESULTS: The image quality for cancer was rated as excellent in the liver, pancreas, kidneys, lungs, pelvic organs, and brain, and rated as fair in the colon and breast. For vascular diseases ratings were excellent in the aorta, major branch vessel origins, inferior vena cava, portal and hepatic veins, rated as good in pulmonary arteries, and as poor in the coronary arteries. For degenerative/inflammatory diseases ratings were excellent in the brain, liver and pancreas. The inter-observer agreement was excellent. CONCLUSION: A comprehensive and time efficient screening for important categories of disease processes may be achieved with high quality imaging in a new generation 48-channel 3T system.

  17. Whole-body MRI: comprehensive evaluation on a 48-channel 3T MRI system in less than 40 minutes. Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Hernandes, Mateus de Andrade; Semelka, Richard C.; Bamrungchart, Saraporn; Stallings, Clifton, E-mail: richsem@med.unc.edu [Department of Radiology, University of North Carolina, Chapel Hill, NC (United States); Elias Junior, Jorge [Imaging and Medical Physics Center, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP (Brazil); Dale, Brian M. [Siemens Medical Solutions USA, Inc., Cary, NC (United States)

    2012-11-15

    Objective: To evaluate a comprehensive MRI protocol that investigates for cancer, vascular disease, and degenerative/inflammatory disease from the head to the pelvis in less than 40 minutes on a new generation 48-channel 3T system. Materials and Methods: All MR studies were performed on a 48-channel 3T MR scanner. A 20-channel head/neck coil, two 18-channel body arrays, and a 32-channel spine array were employed. A total of 4 healthy individuals were studied. The designed protocol included a combination of single-shot T2-weighted sequences, T1-weighted 3D gradient echo pre- and post-gadolinium. All images were retrospectively evaluated by two radiologists independently for overall image quality. Results: The image quality for cancer was rated as excellent in the liver, pancreas, kidneys, lungs, pelvic organs, and brain, and rated as fair in the colon and breast. For vascular diseases ratings were excellent in the aorta, major branch vessel origins, inferior vena cava, portal and hepatic veins, rated as good in pulmonary arteries, and as poor in the coronary arteries. For degenerative/inflammatory diseases ratings were excellent in the brain, liver and pancreas. The inter-observer agreement was excellent. Conclusion: A comprehensive and time efficient screening for important categories of disease processes may be achieved with high quality imaging in a new generation 48-channel 3T system. (author)

  18. Reliability of the Dutch-language version of the Communication Function Classification System and its association with language comprehension and method of communication.

    Science.gov (United States)

    Vander Zwart, Karlijn E; Geytenbeek, Joke J; de Kleijn, Maaike; Oostrom, Kim J; Gorter, Jan Willem; Hidecker, Mary Jo Cooley; Vermeulen, R Jeroen

    2016-02-01

    The aims of this study were to determine the intra- and interrater reliability of the Dutch-language version of the Communication Function Classification System (CFCS-NL) and to investigate the association between the CFCS level and (1) spoken language comprehension and (2) preferred method of communication in children with cerebral palsy (CP). Participants were 93 children with CP (50 males, 43 females; mean age 7y, SD 2y 6mo, range 2y 9mo-12y 10mo; unilateral spastic [n=22], bilateral spastic [n=51], dyskinetic [n=15], ataxic [n=3], not specified [n=2]; Gross Motor Function Classification System level I [n=16], II [n=14], III, [n=7], IV [n=24], V [n=31], unknown [n=1]), recruited from rehabilitation centres throughout the Netherlands. Because some centres only contributed to part of the study, different numbers of participants are presented for different aspects of the study. Parents and speech and language therapists (SLTs) classified the communication level using the CFCS. Kappa was used to determine the intra- and interrater reliability. Spearman's correlation coefficient was used to determine the association between CFCS level and spoken language comprehension, and Fisher's exact test was used to examine the association between the CFCS level and method of communication. Interrater reliability of the CFCS-NL between parents and SLTs was fair (r=0.54), between SLTs good (r=0.78), and the intrarater (SLT) reliability very good (r=0.85). The association between the CFCS and spoken language comprehension was strong for SLTs (r=0.63) and moderate for parents (r=0.51). There was a statistically significant difference between the CFCS level and the preferred method of communication of the child (pcommunication in children with CP. Preferably, professionals should classify the child's CFCS level in collaboration with the parents to acquire the most comprehensive information about the everyday communication of the child in various situations both with familiar and

  19. RDS; A systematic approach towards system thermal hydraulics input code development for a comprehensive deterministic safety analysis

    International Nuclear Information System (INIS)

    Mohd Faiz Salim; Ridha Roslan; Mohd Rizal Mamat

    2013-01-01

    Full-text: Deterministic Safety Analysis (DSA) is one of the mandatory requirements conducted for Nuclear Power Plant licensing process, with the aim of ensuring safety compliance with relevant regulatory acceptance criteria. DSA is a technique whereby a set of conservative deterministic rules and requirements are applied for the design and operation of facilities or activities. Computer codes are normally used to assist in performing all required analysis under DSA. To ensure a comprehensive analysis, the conduct of DSA should follow a systematic approach. One of the methodologies proposed is the Standardized and Consolidated Reference Experimental (and Calculated) Database (SCRED) developed by University of Pisa. Based on this methodology, the use of Reference Data Set (RDS) as a pre-requisite reference document for developing input nodalization was proposed. This paper shall describe the application of RDS with the purpose of assessing its effectiveness. Two RDS documents were developed for an Integral Test Facility of LOBIMOD2 and associated Test A1-83. Data and information from various reports and drawings were referred in preparing the RDS. The results showed that by developing RDS, it has made possible to consolidate all relevant information in one single document. This is beneficial as it enables preservation of information, promotes quality assurance, allows traceability, facilitates continuous improvement, promotes solving of contradictions and finally assisting in developing thermal hydraulic input regardless of whichever code selected. However, some disadvantages were also recognized such as the need for experience in making engineering judgments, language barrier in accessing foreign information and limitation of resources. Some possible improvements are suggested to overcome these challenges. (author)

  20. RDS - A systematic approach towards system thermal hydraulics input code development for a comprehensive deterministic safety analysis

    International Nuclear Information System (INIS)

    Salim, Mohd Faiz; Roslan, Ridha; Ibrahim, Mohd Rizal Mamat

    2014-01-01

    Deterministic Safety Analysis (DSA) is one of the mandatory requirements conducted for Nuclear Power Plant licensing process, with the aim of ensuring safety compliance with relevant regulatory acceptance criteria. DSA is a technique whereby a set of conservative deterministic rules and requirements are applied for the design and operation of facilities or activities. Computer codes are normally used to assist in performing all required analysis under DSA. To ensure a comprehensive analysis, the conduct of DSA should follow a systematic approach. One of the methodologies proposed is the Standardized and Consolidated Reference Experimental (and Calculated) Database (SCRED) developed by University of Pisa. Based on this methodology, the use of Reference Data Set (RDS) as a pre-requisite reference document for developing input nodalization was proposed. This paper shall describe the application of RDS with the purpose of assessing its effectiveness. Two RDS documents were developed for an Integral Test Facility of LOBI-MOD2 and associated Test A1-83. Data and information from various reports and drawings were referred in preparing the RDS. The results showed that by developing RDS, it has made possible to consolidate all relevant information in one single document. This is beneficial as it enables preservation of information, promotes quality assurance, allows traceability, facilitates continuous improvement, promotes solving of contradictions and finally assisting in developing thermal hydraulic input regardless of whichever code selected. However, some disadvantages were also recognized such as the need for experience in making engineering judgments, language barrier in accessing foreign information and limitation of resources. Some possible improvements are suggested to overcome these challenges

  1. RDS - A systematic approach towards system thermal hydraulics input code development for a comprehensive deterministic safety analysis

    Energy Technology Data Exchange (ETDEWEB)

    Salim, Mohd Faiz, E-mail: mohdfaizs@tnb.com.my [Nuclear Energy Department, Tenaga Nasional Berhad, Level 32, Dua Sentral, 50470 Kuala Lumpur (Malaysia); Roslan, Ridha [Nuclear Installation Division, Atomic Energy Licensing Board, Batu 24, Jalan Dengkil, 43800 Dengkil, Selangor (Malaysia); Ibrahim, Mohd Rizal Mamat [Technical Support Division, Malaysian Nuclear Agency, Bangi, 43000 Kajang, Selangor (Malaysia)

    2014-02-12

    Deterministic Safety Analysis (DSA) is one of the mandatory requirements conducted for Nuclear Power Plant licensing process, with the aim of ensuring safety compliance with relevant regulatory acceptance criteria. DSA is a technique whereby a set of conservative deterministic rules and requirements are applied for the design and operation of facilities or activities. Computer codes are normally used to assist in performing all required analysis under DSA. To ensure a comprehensive analysis, the conduct of DSA should follow a systematic approach. One of the methodologies proposed is the Standardized and Consolidated Reference Experimental (and Calculated) Database (SCRED) developed by University of Pisa. Based on this methodology, the use of Reference Data Set (RDS) as a pre-requisite reference document for developing input nodalization was proposed. This paper shall describe the application of RDS with the purpose of assessing its effectiveness. Two RDS documents were developed for an Integral Test Facility of LOBI-MOD2 and associated Test A1-83. Data and information from various reports and drawings were referred in preparing the RDS. The results showed that by developing RDS, it has made possible to consolidate all relevant information in one single document. This is beneficial as it enables preservation of information, promotes quality assurance, allows traceability, facilitates continuous improvement, promotes solving of contradictions and finally assisting in developing thermal hydraulic input regardless of whichever code selected. However, some disadvantages were also recognized such as the need for experience in making engineering judgments, language barrier in accessing foreign information and limitation of resources. Some possible improvements are suggested to overcome these challenges.

  2. Comprehensive analysis and parametric optimization of a CCP (combined cooling and power) system driven by geothermal source

    International Nuclear Information System (INIS)

    Zhao, Yajing; Wang, Jiangfeng; Cao, Liyan; Wang, Yu

    2016-01-01

    A CCP (combined cooling and power) system, which integrated a flash-binary power generation system with a bottom combined cooling and power subsystem operating through the combination of an organic Rankine cycle and an ejector refrigeration cycle, was developed to utilize geothermal energy. Thermodynamic and exergoeconomic analyses were performed on the system. A performance indicator, namely the average levelized costs per unit of exergy products for the overall system, was developed to assess the exergoeconomic performance of the system. The effects of four key parameters including flash pressure, pinch point temperature difference in the vapor generator, inlet pressure and back pressure of the ORC turbine on the system performance were evaluated through a parametric analysis. Two single-objective optimizations were conducted to reach the maximum exergy efficiency and the minimum average levelized costs per unit of exergy products for the overall system, respectively. The optimization results implied that the most exergoeconomically effective system couldn't obtain the best system thermodynamic performance and vice versa. An exergy analysis based on the thermodynamic optimization result revealed that the biggest exergy destruction occurred in the vapor generator and the next two largest exergy destruction were respectively caused by the steam turbine and the flashing device. - Highlights: • A CCP (combined cooling and power) system driven by geothermal source is developed. • Levelized costs per unit of exergy product is used as the exergoeconomic indicator. • Parametric analyses are performed from thermodynamic and exergoeconomic viewpoints. • The optimal exergoeconomic design cannot obtain the best thermodynamic performance. • Exergy analysis is carried out based on the thermodynamic optimization result.

  3. Comprehensive Evaluation on Employee Satisfaction of Mine Occupational Health and Safety Management System Based on Improved AHP and 2-Tuple Linguistic Information

    Directory of Open Access Journals (Sweden)

    Jiangdong Bao

    2017-01-01

    Full Text Available In order to comprehensively evaluate the employee satisfaction of mine occupational health and safety management system, an analytic method based on fuzzy analytic hierarchy process and 2-tuple linguistic model was established. Based on the establishment of 5 first-grade indicators and 20 second-grade ones, method of improved AHP and the time-ordered Weighted Averaging Operator (T-OWA model is constructed. The results demonstrate that the employee satisfaction of the mine occupational health and safety management system is of the ‘general’ rank. The method including the evaluation of employee satisfaction and the quantitative analysis of language evaluation information ensures the authenticity of the language evaluation information.

  4. Renewable energy-driven desalination technologies: A comprehensive review on challenges and potential applications of integrated systems

    KAUST Repository

    Ghaffour, NorEddine; Bundschuh, Jochen; Mahmoudi, Hacè ne; Goosen, Mattheus F A

    2015-01-01

    desalination technologies. Innovative and sustainable desalination processes which are suitable for integrated RE systems are presented. An assessment of the benefits of these technologies and their limitations are also discussed.

  5. Improved mutagen-testing systems in mice: Comprehensive progress report, 1 September 1984 to 31 August 1987

    International Nuclear Information System (INIS)

    Roderick, T.H.

    1987-01-01

    The purpose of this project is to produce improved mutagen-testing systems in mice. Our approach is to produce chromosomal inversion systems in order to improve the techniques necessary to induce, detect, genetically define, and combine inversions in effective and useful mutation-test systems. Another specific objective has been to validate and test the systems produced with respect to their effectiveness in uncovering induced or naturally occurring recessive detrimentals or recessive lethals. Another object has been to mark, maintain, and study these induced recessive lethals induced during the validation-testing. A final broad objective has been to use the induced inversions and recessive lethals for studies of basic problems in mammalian genetics, genetic recombination, gene mapping, fertility, growth, and development

  6. [Effects of the new comprehensive system for designating illegal drug components on the abuse of designer drugs and future problems based on an online questionnaire].

    Science.gov (United States)

    Morino, Taichi; Okazaki, Mitsuhiro; Toda, Takaki; Yokoyama, Takashi

    2015-12-01

    Recently, the abuse of designer drugs has become a social problem. Designer drugs are created by modifying part of the chemical structure of drugs that have already been categorized as illegal, thereby creating a different chemical compound in order to evade Pharmaceutical Affairs Law regulations. The new comprehensive system for designating illegal drug components has been in effect since March 2013, and many designer drugs can now be regulated. We conducted an online questionnaire survey of people with a history of designer drug use to elucidate the effects of the new system on the abuse of designer drugs and to identify potential future problems. Over half the subjects obtained designer drugs only before the new system was implemented. Awareness of the system was significantly lower among subjects who obtained designer drugs for the first time after its introduction than those who obtained the drugs only before its implementation. Due to the new system, all methods of acquiring designer drugs saw decreases in activity. However, the ratio of the acquisition of designer drugs via the Internet increased. Since over 50% of the subjects never obtained designer drugs after the new system was introduced, goals that aimed to make drug procurement more difficult were achieved. However, awareness of the new system among subjects who obtained designer drugs after the new system was introduced was significantly low. Therefore, fostering greater public awareness of the new system is necessary. The results of the questionnaire also suggested that acquiring designer drugs through the Internet has hardly been affected by the new system. We strongly hope that there will be a greater push to restrict the sale of designer drugs on the Internet in the near future.

  7. SITE COMPREHENSIVE LISTING (CERCLIS) (Superfund) - NPL Sites

    Data.gov (United States)

    U.S. Environmental Protection Agency — National Priorities List (NPL) Sites - The Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) (Superfund) Public Access...

  8. Rectal toxicity profile after transperineal interstitial permanent prostate brachytherapy: Use of a comprehensive toxicity scoring system and identification of rectal dosimetric toxicity predictors

    International Nuclear Information System (INIS)

    Shah, Jinesh N.; Ennis, Ronald D.

    2006-01-01

    Purpose: To better understand rectal toxicity after prostate brachytherapy, we employed the National Cancer Institute Common Terminology Criteria for Adverse Events (CTCAE version 3.0), a comprehensive system with distinct and separately reported gastrointestinal adverse event items (unlike Radiation Therapy Oncology Group morbidity scoring), to evaluate item-specific postimplant rectal toxicities. Methods and Materials: We analyzed 135 patients treated with brachytherapy ± hormonal therapy, using CTCAE v3.0 to score acute/late rectal toxicities (median follow-up, 41 months). Dosimetric parameters were evaluated for ability to predict toxicities. Results: Use of CTCAE yielded a novel rectal toxicity profile consisting of diarrhea, incontinence, urgency, proctitis, pain, spasms, and hemorrhage event rates. No item had a 25 (percent of rectal volume receiving 25% of prescribed prostate dose) ≤ 25% vs. 60% for %V 25 > 25% (p 1 ≤ 40% vs. 44% for %V 1 > 40% (p = 0.007). Conclusions: A comprehensive understanding of item-specific postimplant rectal toxicities was obtained using CTCAE. Rectal %V 25 > 25% and %V 1 > 40% predicted worse late diarrhea and maximum toxicity, respectively

  9. SU-E-J-53: A Phantom Design to Assist Patient Position Verification System in Daily Image-Guided RT and Comprehensive QA Measurements

    International Nuclear Information System (INIS)

    Syh, J; Wu, H

    2015-01-01

    Purpose This study is to implement a homemade novel device with surface locking couch index to check daily radiograph (DR) function of adaPTInsight™, stereoscopic image guided system (SIGS), for proton therapy. The comprehensive daily QA checks of proton pencil beam output, field size, flatness and symmetry of spots and energy layers will be followed by using MatriXX dosimetry device. Methods The iBa MatriXX device was used to perform daily dosimetry which is also used to perform SIGS checks. A set of markers were attached to surface of MatriXX device in alignment of DRR of reconstructed CT images and daily DR. The novel device allows MatriXX to be fit into the cradle which was locked by couch index bars on couch surface. This will keep the MatriXX at same XY plane daily with exact coordinates. Couch height Z will be adjusted according to imaging to check isocenter-laser coincidence accuracy. Results adaPTInsight™ provides robotic couch to move in 6-degree coordinate system to align the dosimetry device to be within 1.0 mm / 1.0°. The daily constancy was tightened to be ± 0.5 mm / 0.3° compared to 1.0 mm / 1.0° before. For gantry at 0° and couch all 0° angles (@ Rt ARM 0 setting), offsets measured of the couch systems were ≤ 0.5° in roll, yaw and pitch dimensions. Conclusion Simplicity of novel device made daily image guided QA consistent with accuracy. The offset of the MatriXX isocenter-laser coincident was reproducible. Such easy task not only speeds up the setup, but it increases confidence level in detailed daily comprehensive measurements. The total SIGS alignment time has been shortened with less setup error. This device will enhance our experiences for the future QA when cone beam CT imaging modality becomes available at proton therapy center

  10. Comprehensive safety analysis code system for nuclear fusion reactors III: Ex-vessel LOCA analyses considering passive safety

    International Nuclear Information System (INIS)

    Honda, T.; Okazaki, T.; Maki, K.; Uda, T.; Seki, Y.; Aoki, I.; Kunugi, T.

    1996-01-01

    Ex-vessel loss-of-coolant accidents (LOCAs) in a fusion reactor have been analyzed to investigate the possibility of passive plasma shutdown. For this purpose, a hybrid code of the plasma dynamics and thermal characteristics of the reactor structures, which has been modified to include the impurity emission from plasma-facing components (PFCs), has been developed. Ex-vessel LOCAs of the cooling system during the ignition operation in the International Thermonuclear Experimental Reactor (ITER), in which graphite PFCs were employed in conceptual design activity, were assumed. When double-ended break occurs at the cold leg of the divertor cooling system, the copper cooling tube begins to melt within 3 s after the LOCA, even though the plasma is passively shut down at nearly 4 s. An active plasma shutdown system will be needed for such rapid transient accidents. On the other hand, when a small (1%) break LOCA occurs there, the plasma is passively shut down at nearly 36 s, which happens before the copper cooling tube begins to melt. When the double-ended break LOCA occurs at the cold leg of the first-wall cooling system, there is enough time (nearly 100 s) to shut down the plasma with a controllable method before the reactor structures are damaged. 21 refs., 8 figs

  11. Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity

    NARCIS (Netherlands)

    Tsang-A-Sjoe, M. W. P.; Bultink, I. E. M.; Korswagen, L. A.; van der Horst, A. [=Anneke; Rensink, I.; de Boer, M.; Hamann, D.; Voskuyl, A. E.; Wouters, D.

    2017-01-01

    Genetic variation of the genes encoding complement component C4 is strongly associated with systemic lupus erythematosus (SLE), a chronic multi-organ auto-immune disease. This study examined C4 and its isotypes on a genetic, protein, and functional level in 140 SLE patients and 104 healthy controls.

  12. Monte Carlo Techniques for the Comprehensive Modeling of Isotopic Inventories in Future Nuclear Systems and Fuel Cycles. Final Report

    International Nuclear Information System (INIS)

    Paul P.H. Wilson

    2005-01-01

    The development of Monte Carlo techniques for isotopic inventory analysis has been explored in order to facilitate the modeling of systems with flowing streams of material through varying neutron irradiation environments. This represents a novel application of Monte Carlo methods to a field that has traditionally relied on deterministic solutions to systems of first-order differential equations. The Monte Carlo techniques were based largely on the known modeling techniques of Monte Carlo radiation transport, but with important differences, particularly in the area of variance reduction and efficiency measurement. The software that was developed to implement and test these methods now provides a basis for validating approximate modeling techniques that are available to deterministic methodologies. The Monte Carlo methods have been shown to be effective in reproducing the solutions of simple problems that are possible using both stochastic and deterministic methods. The Monte Carlo methods are also effective for tracking flows of materials through complex systems including the ability to model removal of individual elements or isotopes in the system. Computational performance is best for flows that have characteristic times that are large fractions of the system lifetime. As the characteristic times become short, leading to thousands or millions of passes through the system, the computational performance drops significantly. Further research is underway to determine modeling techniques to improve performance within this range of problems. This report describes the technical development of Monte Carlo techniques for isotopic inventory analysis. The primary motivation for this solution methodology is the ability to model systems of flowing material being exposed to varying and stochastically varying radiation environments. The methodology was developed in three stages: analog methods which model each atom with true reaction probabilities (Section 2), non-analog methods

  13. A comprehensive economic evaluation of integrated desalination systems using fossil fuelled and nuclear energies and including their environmental costs

    International Nuclear Information System (INIS)

    Nisan, S.; Benzarti, N.

    2008-01-01

    Seawater desalination is now widely accepted as an attractive alternative source of freshwater for domestic and industrial uses. Despite the considerable progress made in the relevant technologies desalination, however, remains an energy intensive process in which the energy cost is the paramount factor. This Study is a first of a kind in that we have integrated the environmental costs into the power and desalination costs. The study has focused on the seawater desalination cost evaluation of the following systems. It is supposed that they will be operating in the co-generation mode (Simultaneous production of electrical power and desalted water) in 2015: Fossil fuelled based systems such as the coal and oil fired plants and the gas turbine combined cycle plant, coupled to MED, and RO; Pressurised water reactors such as the PWR-900 and the AP-600, coupled to MED, and RO; High temperature reactors such as the GT-MHR, the PBMR, coupled to MED, with the utilisation of virtually free waste-heat provided by these reactors. The study is made in real site-specific conditions of a site In Southern Europe. Sensitivity studies for different parameters such as the fossil fuel prices, interest and discount rates, power costs etc., have also been undertaken. The results obtained are then used to evaluate the financial interest of selected integrated desalination systems in terms of a detailed cash flow analysis, providing the net present values, pay back periods and the internal rate of returns. Analysis of the results shows that among the fossil fuelled systems the power and desalination costs by circulating fluidized bed coal fired plant would be the lowest with current coal prices. Those by oil fired plants would be highest. In all cases, integrated nuclear energy systems would lead to considerably lower power and water costs than the corresponding coal based systems. When external costs for different energies are internalized in power and water costs, the relative cost

  14. Framework for Establishment of a Comprehensive and Standardized Administration System for Prevention and Control of Tuberculosis in College Student Community in China.

    Science.gov (United States)

    Zhang, Shaoru; Li, Xiaohong; Zhang, Tianhua; Wang, Xiangni; Liu, Weiping; Ma, Xuexue; Li, Yuelu; Fan, Yahui

    2016-10-01

    College student community is the one with high risk of tuberculosis (TB). A systemic and standardized administration model for prevention and control of TB is significance in controlling TB spread in universities. Currently, the universities in China have not established the comprehensive and standardized administration system for TB prevention and control in college student community. Firstly, the literature research and brainstorming method (n=13) were used to construct the clause and sub-clause pool for the administration of TB prevention and control within college student community in 2014. Secondly, a total of twenty experts in the field of TB prevention and control who are representatives of the east, west, south and north parts of China were selected and invited to participate the Delphi letter-inquiry. After two rounds of letter-inquiry, the opinions of the experts reached a consensus and the framework for the administration system was constructed. A framework for the administration system was constructed, which included 8 first class indexes, 26 second class indexes and 104 third class indexes. The results are highly scientific and reliable, which can be helpful for improving the systemic and standardized levels for the administration of TB prevention and control in universities in China and perhaps in other developing counties with high TB burden as well.

  15. Assessment of Comprehensive Effects and Optimization of a Circular Economy System of Coal Power and Cement in Kongtong District, Pingliang City, Gansu Province, China

    Directory of Open Access Journals (Sweden)

    Suocheng Dong

    2017-05-01

    Full Text Available The idea of a circular economy (CE, which differs from traditional linear economy with a high consumption of natural resources and pollution, has captured much interest and attention. This paper uses a CE system of coal power and cement in Kongtong District, Pingliang City, Gansu Province, China as a case study to analyze the comprehensive effects of CE paradigm. Our simulation results, based on system dynamics (SD modeling, infer that the transformation of manufacturing towards a CE system can prominently help coal power and cement enterprises reduce waste emission and increase economic profits. Through solid waste exchanges, a power plant can achieve over RMB 80 million of additional revenue per year at the highest level. CE also contributes to the reduction of regional pollution, saves mineral resources, and improves the atmospheric environment, an accumulated total of 14.11 million t of natural gypsum and 22.67 million t of coal can be saved. This sets a promising example for coal power and cement plants worldwide. Effective regulatory measures and further optimization towards a circular economy system are essential in maintaining the stable development of a CE system due to the risk of surplus production of upstream industries and other defects.

  16. A comprehensive, multi-objective optimization of solar-powered absorption chiller systems for air-conditioning applications

    International Nuclear Information System (INIS)

    Shirazi, Ali; Taylor, Robert A.; Morrison, Graham L.; White, Stephen D.

    2017-01-01

    Highlights: • Multi-objective optimization of solar single/multi-effect absorption chillers was conducted. • Primary energy consumption and total annual cost were considered as the objectives. • Optimized designs of the alternative configurations were compared. • A detailed sensitivity analysis of the Pareto optimal solutions was investigated. - Abstract: Solar heating and cooling (SHC) systems are currently under rapid development and deployment due to their potential to reduce the use of fossil fuel resources and to alleviate greenhouse gas emissions in the building sector – a sector which is responsible for ∼40% of the world energy use. Absorption chiller technology (traditionally powered by natural gas in large buildings), can easily be retrofitted to run on solar energy. However, numerous non-intuitive design choices must be analyzed to achieve the best techno-economic performance of these systems. To date, there has been little research into the optimal configurations among the long list of potential solar-driven absorption chiller systems. To address this lack of knowledge, this paper presents a systematic simulation-based, multi-objective optimization of three common, commercially available lithium bromide-water absorption chillers – single-effect, double-effect and triple-effect – powered by evacuated tube collectors (ETCs), evacuated flat plate collectors (EFPCs), and concentrating parabolic trough collectors (PTCs), respectively. To the best of authors’ knowledge, this is the first study of its kind that compares the optimized designs of the most promising configurations of solar-assisted absorption chillers against a common set of energy, economic, and environmental metrics from a holistic perspective. A simulation model of these three configurations is developed using TRNSYS 17. A combined energy, economic, and environmental analysis of the modeled systems is conducted to calculate the primary energy use as well as the levelized total

  17. New Python-based methods for data processing

    International Nuclear Information System (INIS)

    Sauter, Nicholas K.; Hattne, Johan; Grosse-Kunstleve, Ralf W.; Echols, Nathaniel

    2013-01-01

    The Computational Crystallography Toolbox (cctbx) is a flexible software platform that has been used to develop high-throughput crystal-screening tools for both synchrotron sources and X-ray free-electron lasers. Plans for data-processing and visualization applications are discussed, and the benefits and limitations of using graphics-processing units are evaluated. Current pixel-array detectors produce diffraction images at extreme data rates (of up to 2 TB h −1 ) that make severe demands on computational resources. New multiprocessing frameworks are required to achieve rapid data analysis, as it is important to be able to inspect the data quickly in order to guide the experiment in real time. By utilizing readily available web-serving tools that interact with the Python scripting language, it was possible to implement a high-throughput Bragg-spot analyzer (cctbx.spotfinder) that is presently in use at numerous synchrotron-radiation beamlines. Similarly, Python interoperability enabled the production of a new data-reduction package (cctbx.xfel) for serial femtosecond crystallography experiments at the Linac Coherent Light Source (LCLS). Future data-reduction efforts will need to focus on specialized problems such as the treatment of diffraction spots on interleaved lattices arising from multi-crystal specimens. In these challenging cases, accurate modeling of close-lying Bragg spots could benefit from the high-performance computing capabilities of graphics-processing units

  18. New Python-based methods for data processing

    Energy Technology Data Exchange (ETDEWEB)

    Sauter, Nicholas K., E-mail: nksauter@lbl.gov; Hattne, Johan; Grosse-Kunstleve, Ralf W.; Echols, Nathaniel [Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720 (United States)

    2013-07-01

    The Computational Crystallography Toolbox (cctbx) is a flexible software platform that has been used to develop high-throughput crystal-screening tools for both synchrotron sources and X-ray free-electron lasers. Plans for data-processing and visualization applications are discussed, and the benefits and limitations of using graphics-processing units are evaluated. Current pixel-array detectors produce diffraction images at extreme data rates (of up to 2 TB h{sup −1}) that make severe demands on computational resources. New multiprocessing frameworks are required to achieve rapid data analysis, as it is important to be able to inspect the data quickly in order to guide the experiment in real time. By utilizing readily available web-serving tools that interact with the Python scripting language, it was possible to implement a high-throughput Bragg-spot analyzer (cctbx.spotfinder) that is presently in use at numerous synchrotron-radiation beamlines. Similarly, Python interoperability enabled the production of a new data-reduction package (cctbx.xfel) for serial femtosecond crystallography experiments at the Linac Coherent Light Source (LCLS). Future data-reduction efforts will need to focus on specialized problems such as the treatment of diffraction spots on interleaved lattices arising from multi-crystal specimens. In these challenging cases, accurate modeling of close-lying Bragg spots could benefit from the high-performance computing capabilities of graphics-processing units.

  19. A comprehensive data acquisition and management system for an ecosystem-scale peatland warming and elevated CO2 experiment

    Science.gov (United States)

    Krassovski, M. B.; Riggs, J. S.; Hook, L. A.; Nettles, W. R.; Hanson, P. J.; Boden, T. A.

    2015-11-01

    Ecosystem-scale manipulation experiments represent large science investments that require well-designed data acquisition and management systems to provide reliable, accurate information to project participants and third party users. The SPRUCE project (Spruce and Peatland Responses Under Climatic and Environmental Change, http://mnspruce.ornl.gov) is such an experiment funded by the Department of Energy's (DOE), Office of Science, Terrestrial Ecosystem Science (TES) Program. The SPRUCE experimental mission is to assess ecosystem-level biological responses of vulnerable, high carbon terrestrial ecosystems to a range of climate warming manipulations and an elevated CO2 atmosphere. SPRUCE provides a platform for testing mechanisms controlling the vulnerability of organisms, biogeochemical processes, and ecosystems to climatic change (e.g., thresholds for organism decline or mortality, limitations to regeneration, biogeochemical limitations to productivity, and the cycling and release of CO2 and CH4 to the atmosphere). The SPRUCE experiment will generate a wide range of continuous and discrete measurements. To successfully manage SPRUCE data collection, achieve SPRUCE science objectives, and support broader climate change research, the research staff has designed a flexible data system using proven network technologies and software components. The primary SPRUCE data system components are the following: 1. data acquisition and control system - set of hardware and software to retrieve biological and engineering data from sensors, collect sensor status information, and distribute feedback to control components; 2. data collection system - set of hardware and software to deliver data to a central depository for storage and further processing; 3. data management plan - set of plans, policies, and practices to control consistency, protect data integrity, and deliver data. This publication presents our approach to meeting the challenges of designing and constructing an

  20. Comprehensive Utilization Technology of Solar Wall System%太阳墙系统综合利用技术

    Institute of Scientific and Technical Information of China (English)

    任庚坡; 房玉娜

    2014-01-01

    With the worsening of energy situation,renewable energy including solar is increasingly concerned . This article introduces the general situation of utilization of solar energy and a new kind of solar thermal tech-nology---solar wall system.The paper illustrates the working principles and features of the solar wall sys-tem,with cases of factory building and general building respectively.In the last part,the paper analyses the economics and Promotion potential for replication of solar wall system.Solar Wall system has good economic returns,high thermal efficiency and good fresh air effect.By combining the rooftop photovoltaic system and solar wall,photovoltaic/solar thermal utilization can be achieved,and the utilization of solar energy is im-proved.%介绍了太阳能利用概况及一种新的太阳能热利用技术---太阳墙系统,阐述其工作原理及特点,并列举在厂房和一般建筑的应用案例,分析了太阳墙的经济性和推广潜力。太阳墙系统具有经济效益好、热效率高、新风效果好的优点;通过屋顶光伏发电系统与太阳墙的结合,可实现光电/光热综合利用,提高太阳能利用率。

  1. Bolsa Bay, California, Proposed Ocean Entrance System Study. Report 2. Comprehensive Shoreline Response Computer Simulation, Bolsa Bay, California

    Science.gov (United States)

    1990-04-01

    Southern California Bight is affected by a land-sea breeze pattern. A variation in flow is caused by the heating of the land surface during the day, and...1980). 27. The success of the inlet channel at Agua Hedionda indicates that a stable non-navigable entrance at Bolsa Chica could be feasible provided a...dual jetty system similar to Agua Hedionda is incorporated into the design. However, structures that penetrate into the active surf zone are expected

  2. Comprehensive monitoring system - essential tool to show the results of the energy audit and voluntary agreement programmes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    Without visible results political support to an energy efficiency programme will dissolve in a few years. Therefore high-quality monitoring and reporting systems are essential to maintain a long-term commitment. Both in Finnish Energy Audit Programme (EAP), began in 1992, and in Voluntary Agreement Scheme (VA), began in 1997, bottom-up monitoring systems have been in place almost since the beginning. These policy measures and their monitoring systems are integrated. For the EAP monitoring system data is collected in three phases: subsidies granted; the energy auditing volumes in different sectors submitted EA reports; proposed measures and saving potentials. VA annual reporting; status of implementation of the proposed measures in EA reports and implementing rate for saving potentials. In VA scheme the companies and communities report annually on their energy consumption and on energy efficiency measures they have implemented or have decided to implement. Information on energy savings in energy units and energy costs as well as the required investment is reported in connection to the presented measures. The collected data is based on engineering calculations by the energy auditors. Since the companies have no incentives to submit exaggerated savings, the reported savings are equal to those figures the companies have used as criteria when deciding on the implementation of the measures. By 2005 these two policy measures have generated about 7 TWh annual savings, representing over 2 % of Finland's total energy end-use. In relation to the magnitude of savings brought in daylight, the investment on monitoring has really paid back.

  3. Toward acquiring comprehensive radiosurgery field commissioning data using the PRESAGE/optical-CT 3D dosimetry system

    Energy Technology Data Exchange (ETDEWEB)

    Clift, Corey; Thomas, Andrew; Chang Zheng; Oldham, Mark [Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710 (United States); Adamovics, John [Department of Chemistry, Rider University, Lawrenceville, NJ 08648 (United States); Das, Indra [Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202 (United States)], E-mail: cclift@montefiore.org

    2010-03-07

    Achieving accurate small field dosimetry is challenging. This study investigates the utility of a radiochromic plastic PRESAGE read with optical-CT for the acquisition of radiosurgery field commissioning data from a Novalis Tx system with a high-definition multileaf collimator (HDMLC). Total scatter factors (S{sub c,p}), beam profiles, and penumbrae were measured for five different radiosurgery fields (5, 10, 20, 30 and 40 mm) using a commercially available optical-CT scanner (OCTOPUS, MGS Research). The percent depth dose (PDD), beam profile and penumbra of the 10 mm field were also measured using a higher resolution in-house prototype CCD-based scanner. Gafchromic EBT film was used for independent verification. Measurements of S{sub c,p} made with PRESAGE and film agreed with mini-ion chamber commissioning data to within 4% for every field (range 0.2-3.6% for PRESAGE, and 1.6-3.6% for EBT). PDD, beam profile and penumbra measurements made with the two PRESAGE/optical-CT systems and film showed good agreement with the high-resolution diode commissioning measurements with a competitive resolution (0.5 mm pixels). The in-house prototype optical-CT scanner allowed much finer resolution compared with previous applications of PRESAGE. The advantages of the PRESAGE (registered) system for small field dosimetry include 3D measurements, negligible volume averaging, directional insensitivity, an absence of beam perturbations, energy and dose rate independence.

  4. The PAXgene(® tissue system preserves phosphoproteins in human tissue specimens and enables comprehensive protein biomarker research.

    Directory of Open Access Journals (Sweden)

    Sibylle Gündisch

    Full Text Available Precise quantitation of protein biomarkers in clinical tissue specimens is a prerequisite for accurate and effective diagnosis, prognosis, and personalized medicine. Although progress is being made, protein analysis from formalin-fixed and paraffin-embedded tissues is still challenging. In previous reports, we showed that the novel formalin-free tissue preservation technology, the PAXgene Tissue System, allows the extraction of intact and immunoreactive proteins from PAXgene-fixed and paraffin-embedded (PFPE tissues. In the current study, we focused on the analysis of phosphoproteins and the applicability of two-dimensional gel electrophoresis (2D-PAGE and enzyme-linked immunosorbent assay (ELISA to the analysis of a variety of malignant and non-malignant human tissues. Using western blot analysis, we found that phosphoproteins are quantitatively preserved in PFPE tissues, and signal intensities are comparable to that in paired, frozen tissues. Furthermore, proteins extracted from PFPE samples are suitable for 2D-PAGE and can be quantified by ELISA specific for denatured proteins. In summary, the PAXgene Tissue System reliably preserves phosphoproteins in human tissue samples, even after prolonged fixation or stabilization times, and is compatible with methods for protein analysis such as 2D-PAGE and ELISA. We conclude that the PAXgene Tissue System has the potential to serve as a versatile tissue fixative for modern pathology.

  5. Toward acquiring comprehensive radiosurgery field commissioning data using the PRESAGE/optical-CT 3D dosimetry system

    International Nuclear Information System (INIS)

    Clift, Corey; Thomas, Andrew; Chang Zheng; Oldham, Mark; Adamovics, John; Das, Indra

    2010-01-01

    Achieving accurate small field dosimetry is challenging. This study investigates the utility of a radiochromic plastic PRESAGE read with optical-CT for the acquisition of radiosurgery field commissioning data from a Novalis Tx system with a high-definition multileaf collimator (HDMLC). Total scatter factors (S c,p ), beam profiles, and penumbrae were measured for five different radiosurgery fields (5, 10, 20, 30 and 40 mm) using a commercially available optical-CT scanner (OCTOPUS, MGS Research). The percent depth dose (PDD), beam profile and penumbra of the 10 mm field were also measured using a higher resolution in-house prototype CCD-based scanner. Gafchromic EBT film was used for independent verification. Measurements of S c,p made with PRESAGE and film agreed with mini-ion chamber commissioning data to within 4% for every field (range 0.2-3.6% for PRESAGE, and 1.6-3.6% for EBT). PDD, beam profile and penumbra measurements made with the two PRESAGE/optical-CT systems and film showed good agreement with the high-resolution diode commissioning measurements with a competitive resolution (0.5 mm pixels). The in-house prototype optical-CT scanner allowed much finer resolution compared with previous applications of PRESAGE. The advantages of the PRESAGE (registered) system for small field dosimetry include 3D measurements, negligible volume averaging, directional insensitivity, an absence of beam perturbations, energy and dose rate independence.

  6. Toward acquiring comprehensive radiosurgery field commissioning data using the PRESAGE®/ optical-CT 3D dosimetry system

    Science.gov (United States)

    Clift, Corey; Thomas, Andrew; Adamovics, John; Chang, Zheng; Das, Indra; Oldham, Mark

    2010-03-01

    Achieving accurate small field dosimetry is challenging. This study investigates the utility of a radiochromic plastic PRESAGE® read with optical-CT for the acquisition of radiosurgery field commissioning data from a Novalis Tx system with a high-definition multileaf collimator (HDMLC). Total scatter factors (Sc, p), beam profiles, and penumbrae were measured for five different radiosurgery fields (5, 10, 20, 30 and 40 mm) using a commercially available optical-CT scanner (OCTOPUS, MGS Research). The percent depth dose (PDD), beam profile and penumbra of the 10 mm field were also measured using a higher resolution in-house prototype CCD-based scanner. Gafchromic EBT® film was used for independent verification. Measurements of Sc, p made with PRESAGE® and film agreed with mini-ion chamber commissioning data to within 4% for every field (range 0.2-3.6% for PRESAGE®, and 1.6-3.6% for EBT). PDD, beam profile and penumbra measurements made with the two PRESAGE®/optical-CT systems and film showed good agreement with the high-resolution diode commissioning measurements with a competitive resolution (0.5 mm pixels). The in-house prototype optical-CT scanner allowed much finer resolution compared with previous applications of PRESAGE®. The advantages of the PRESAGE® system for small field dosimetry include 3D measurements, negligible volume averaging, directional insensitivity, an absence of beam perturbations, energy and dose rate independence.

  7. Music intervention as system: reversing hyper systemising in autism spectrum disorders to the comprehension of music as intervention.

    Science.gov (United States)

    Jaschke, Artur C

    2014-01-01

    This paper seeks to combine the notion of the Empathising-Systemising (E-S) theory and the resulting twist from the executive dysfunction theory in autism spectrum conditions (ASC) in light of music intervention as system. To achieve these points it will be important to re-visit, nonetheless briefly, the above mentioned theories and re-define music intervention in the light of these. Furthermore there is the need to adjust the executive dysfunction theory to a theory of dysfunctioning executive functions. These notions will create a different understanding of music intervention in this context, allowing the development of future and existing music intervention programs applied clinically. These applications will evolve around a structuralised approach to music intervention as system, proposing five consecutive systems. It will therefore argue the aspects of expanding existing theories in ASC together with the call for generalised interventions to better assess autism from a theoretical point of view. Theories have to be updated in a time of fast and ever-changing development. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Comprehensive theory of the Deans' switch as a variable flow splitter: fluid mechanics, mass balance, and system behavior.

    Science.gov (United States)

    Boeker, Peter; Leppert, Jan; Mysliwietz, Bodo; Lammers, Peter Schulze

    2013-10-01

    The Deans' switch is an effluent switching device based on controlling flows of carrier gas instead of mechanical valves in the analytical flow path. This technique offers high inertness and a wear-free operation. Recently new monolithic microfluidic devices have become available. In these devices the whole flow system is integrated into a small metal device with low thermal mass and leak-tight connections. In contrast to a mechanical valve-based system, a flow-controlled system is more difficult to calculate. Usually the Deans' switch is used to switch one inlet to one of two outlets, by means of two auxiliary flows. However, the Deans' switch can also be used to deliver the GC effluent with a specific split ratio to both outlets. The calculation of the split ratio of the inlet flow to the two outlets is challenging because of the asymmetries of the flow resistances. This is especially the case, if one of the outlets is a vacuum device, such as a mass spectrometer, and the other an atmospheric detector, e.g. a flame ionization detector (FID) or an olfactory (sniffing) port. The capillary flows in gas chromatography are calculated with the Hagen-Poiseuille equation of the laminar, isothermal and compressible flow in circular tubes. The flow resistances in the new microfluidic devices have to be calculated with the corresponding equation for rectangular cross-section microchannels. The Hagen-Poiseuille equation underestimates the flow to a vacuum outlet. A corrected equation originating from the theory of rarefied flows is presented. The calculation of pressures and flows of a Deans' switch based chromatographic system is done by the solution of mass balances. A specific challenge is the consideration of the antidiffusion resistor between the two auxiliary gas lines of the Deans' switch. A full solution for the calculation of the Deans' switch including this restrictor is presented. Results from validation measurements are in good accordance with the developed

  9. Renewable energy-driven desalination technologies: A comprehensive review on challenges and potential applications of integrated systems

    KAUST Repository

    Ghaffour, Noreddine

    2015-01-01

    Despite the tremendous improvements in conventional desalination technologies, its wide use is still limited due primarily to high energy requirements which are currently met with expensive fossil fuels. The use of alternative energy sources is essential to meet the growing demand for water desalination. In the last few decades a lot of effort has being directed in the use of different renewable energy (RE) sources to run desalination processes. However, the expansion of these efforts towards larger scale plants is hampered by several techno-economic challenges. Several medium-scale RE-driven desalination plants have been installed worldwide. Nevertheless, most of these plants are connected to the electrical grid to assure a continuous energy supply for stable operation. Furthermore, RE is mostly used to produce electric power which can be used to run desalination systems. This review paper focuses on an integrated approach in using RE-driven with an emphasis on solar and geothermal desalination technologies. Innovative and sustainable desalination processes which are suitable for integrated RE systems are presented. An assessment of the benefits of these technologies and their limitations are also discussed.

  10. A Comprehensive Software and Database Management System for Glomerular Filtration Rate Estimation by Radionuclide Plasma Sampling and Serum Creatinine Methods.

    Science.gov (United States)

    Jha, Ashish Kumar

    2015-01-01

    Glomerular filtration rate (GFR) estimation by plasma sampling method is considered as the gold standard. However, this method is not widely used because the complex technique and cumbersome calculations coupled with the lack of availability of user-friendly software. The routinely used Serum Creatinine method (SrCrM) of GFR estimation also requires the use of online calculators which cannot be used without internet access. We have developed user-friendly software "GFR estimation software" which gives the options to estimate GFR by plasma sampling method as well as SrCrM. We have used Microsoft Windows(®) as operating system and Visual Basic 6.0 as the front end and Microsoft Access(®) as database tool to develop this software. We have used Russell's formula for GFR calculation by plasma sampling method. GFR calculations using serum creatinine have been done using MIRD, Cockcroft-Gault method, Schwartz method, and Counahan-Barratt methods. The developed software is performing mathematical calculations correctly and is user-friendly. This software also enables storage and easy retrieval of the raw data, patient's information and calculated GFR for further processing and comparison. This is user-friendly software to calculate the GFR by various plasma sampling method and blood parameter. This software is also a good system for storing the raw and processed data for future analysis.

  11. A comprehensive assessment of ionospheric gradients observed in Ecuador during 2013 and 2014 for ground based augmentation systems

    Science.gov (United States)

    Sánchez-Naranjo, S.; Rincón, W.; Ramos-Pollán, R.; González, F. A.; Soley, S.

    2017-04-01

    Ground Based Augmentation Systems GBAS provide differential corrections to approaching and landing aircrafts in the vicinities of an airport. The ionosphere can introduce an error not accountable by those differential corrections, and a threat model for the Conterminous United States region CONUS was developed in order to consider the highest gradients measured. This study presents the first extensive analysis of ionospheric gradients for Ecuador, from data fully covering 2013 and 2014 collected by their national Global Navigation Satellite System GNSS monitoring network (REGME). In this work it is applied an automated methodology adapted for low latitudes for processing data from dual frequency receivers networks, by considering data from all available days in the date range of the study regardless the geomagnetic indices values. The events found above the CONUS threat model occurred during days of nominal geomagnetic indices, confirming: (1) the higher bounds required for an ionospheric threat model for Ecuador, and (2) that geomagnetic indices are not enough to indicate relevant ionospheric anomalies in low latitude regions, reinforcing the necessity of a continuous monitoring of ionosphere. As additional contribution, the events database is published online, making it available to other researchers.

  12. Comprehensive metabolic panel

    Science.gov (United States)

    Metabolic panel - comprehensive; Chem-20; SMA20; Sequential multi-channel analysis with computer-20; SMAC20; Metabolic panel 20 ... Chernecky CC, Berger BJ. Comprehensive metabolic panel (CMP) - blood. In: ... Tests and Diagnostic Procedures . 6th ed. St Louis, MO: ...

  13. Comprehensive energy management eco routing & velocity profiles

    CERN Document Server

    Brandstätter, Bernhard

    2017-01-01

    The book discusses the emerging topic of comprehensive energy management in electric vehicles from the viewpoint of academia and from the industrial perspective. It provides a seamless coverage of all relevant systems and control algorithms for comprehensive energy management, their integration on a multi-core system and their reliability assurance (validation and test). Relevant European projects contributing to the evolvement of comprehensive energy management in fully electric vehicles are also included.

  14. Memory mechanisms supporting syntactic comprehension.

    Science.gov (United States)

    Caplan, David; Waters, Gloria

    2013-04-01

    Efforts to characterize the memory system that supports sentence comprehension have historically drawn extensively on short-term memory as a source of mechanisms that might apply to sentences. The focus of these efforts has changed significantly in the past decade. As a result of changes in models of short-term working memory (ST-WM) and developments in models of sentence comprehension, the effort to relate entire components of an ST-WM system, such as those in the model developed by Baddeley (Nature Reviews Neuroscience 4: 829-839, 2003) to sentence comprehension has largely been replaced by an effort to relate more specific mechanisms found in modern models of ST-WM to memory processes that support one aspect of sentence comprehension--the assignment of syntactic structure (parsing) and its use in determining sentence meaning (interpretation) during sentence comprehension. In this article, we present the historical background to recent studies of the memory mechanisms that support parsing and interpretation and review recent research into this relation. We argue that the results of this research do not converge on a set of mechanisms derived from ST-WM that apply to parsing and interpretation. We argue that the memory mechanisms supporting parsing and interpretation have features that characterize another memory system that has been postulated to account for skilled performance-long-term working memory. We propose a model of the relation of different aspects of parsing and interpretation to ST-WM and long-term working memory.

  15. Comprehensive study of rheological and surface properties of the selected slag system in the context of its internal structure

    Directory of Open Access Journals (Sweden)

    L. Řeháčková

    2016-10-01

    Full Text Available Rheological (dynamic viscosity, flow curves and surface properties (surface tension of real slag system were experimentally investigated. Measurements of dynamic viscosity were performed with use of the high-temperature viscometer Anton Paar FRS 1 600. The method of sessile drop was used for measurement of surface tension. Surface tension and dynamic viscosity were measured in the temperature interval from 1 200 to 1 600 °C. The structural characteristics of the selected samples were determined by X-ray diffraction (XRD. The samples for given analysis were prepared by quench cooling. Experimentally determined values of dynamic viscosity and surface tension were compared with the results of X-ray diffraction phase analysis.

  16. Securing the long-term financing of decommissioning and radioactive waste management - From cost estimates to a comprehensive financing system

    International Nuclear Information System (INIS)

    Aebersold, Michael

    2003-01-01

    One of the most important issues in the area of waste disposal concerns the long-term securing of the necessary financing. Large amounts of money will have to be invested, managed and subsequently spent at the appropriate time, over an extended period of 100 years or more. In an electricity market that is opening up across Europe and is characterised by complicated legal structures, a focus on a handful of major groups and cost pressure due to increased competition, it will be necessary to create the corresponding background conditions. The anticipated costs for decommissioning and disposal will have to be calculated or estimated on the basis of available know-how and criteria. The required funds will then have to be collected and invested on the domestic and international money markets, which given the current situation on the stock markets will by no means be an easy task. But the assurance that enough money will be available is essential for public confidence. Using Switzerland as an example, the author wishes to demonstrate which steps are necessary in order to calculate the potential decommissioning and waste disposal costs based on a defined disposal concept and programme, determine the annual contributions to be paid in by operators, and establish a suitable system for securing the necessary funding. This paper deals with the following issues: 1. Political background and legislative framework in Switzerland; 2. Swiss radioactive waste management policy and programmes; 3. Calculating the decommissioning and waste management costs; 4. Calculating the contributions to the Funds; 5. Financing system

  17. A comprehensive in vitro and in vivo evaluation of thiolated matrix tablets as a gastroretentive delivery system.

    Science.gov (United States)

    Senyigit, Zeynep Ay; Vetter, Anja; Guneri, Tamer; Bernkop-Schnürch, Andreas

    2011-08-01

    The aim of this study was to investigate the potential of thiolated matrix tablets for gastroretentive delivery systems. Poly(acrylic acid)-cysteine (PAA-Cys) and chitosan-4-thiobuthylamidine (chitosan-TBA) were evaluated as anionic and cationic thiolated polymers and riboflavin was used as a model drug. Tablets were prepared by direct compression and each formulation was characterized in terms of disintegration, swelling, mucoadhesion, and drug release properties. Thereafter, the gastric residence times of tablets were determined with in vivo study in rats. The resulting PAA-Cys and chitosan-TBA conjugates displayed 172.80 ± 30.33 and 371.11 ± 72.74 µmol free thiol groups, respectively. Disintegration studies demonstrated the stability of thiolated tablets up to 24 h, whereas tablets prepared with unmodified PAA and chitosan disintegrated within a time period of 1 h. Mucoadhesion studies showed that mucoadhesion work of PAA-Cys and chitosan-TBA tablets were 1.341- and 2.139-times higher than unmodified ones. The mucoadhesion times of PAA, PAA-Cys, chitosan, and chitosan-TBA tablets were 1.5 ± 0.5, 21 ± 1, 1 ± 0.5, 17 ± 1 h, respectively. These results confirm the theory that thiol groups react with mucin glycoproteins and form covalent bonds to the mucus layer. Release studies indicated that a controlled release was provided with thiolated tablets up to 24 h. These promising in vitro results of thiolated tablets were proved with in vivo studies. The thiolated tablets showed a gastroretention time up to 6 h, whereas unmodified tablets completely disintegrated within 1 h in rat stomach. Consequently, the study suggests that thiolated matrix tablets might be promising formulations for gastroretentive delivery systems.

  18. A Comprehensive Program to Reduce Rates of Hospital-Acquired Pressure Ulcers in a System of Community Hospitals.

    Science.gov (United States)

    Englebright, Jane; Westcott, Ruth; McManus, Kathryn; Kleja, Kacie; Helm, Colleen; Korwek, Kimberly M; Perlin, Jonathan B

    2018-03-01

    The prevention of hospital-acquired pressure ulcers (PrUs) has significant consequences for patient outcomes and the cost of care. Providers are challenged with evaluating available evidence and best practices, then implementing programs and motivating change in various facility environments. In a large system of community hospitals, the Reducing Hospital Acquired-PrUs Program was developed to provide a toolkit of best practices, timely and appropriate data for focusing efforts, and continuous implementation support. Baseline data on PrU rates helped focus efforts on the most vulnerable patients and care situations. Facilities were empowered to use and adapt available resources to meet local needs and to share best practices for implementation across the system. Outcomes were measured by the rate of hospital-acquired PrUs, as gathered from patient discharge records. The rate of hospital-acquired stage III and IV PrUs decreased 66.3% between 2011 and 2013. Of the 149 participating facilities, 40 (27%) had zero hospital-acquired stage III and IV PrUs and 77 (52%) had a reduction in their PrU rate. Rates of all PrUs documented as present on admission did not change during this period. A comparison of different strategies used by the most successful facilities illustrated the necessity of facility-level flexibility and recognition of local workflows and patient demographics. Driven by the combination of a repository of evidence-based tools and best practices, readily available data on PrU rates, and local flexibility with processes, the Reducing Hospital Acquired-PrUs Program represents the successful operationalization of improvement in a wide variety of facilities.

  19. A comprehensive study on photocatalytic activity of supported Ni/Pb sulfide and oxide systems onto natural zeolite nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Babaahamdi-Milani, Majid [Department of Chemistry, Shahreza Branch, Islamic Azad University, P.O. Box 311-86145, Shahreza, Isfahan (Iran, Islamic Republic of); Young Researchers and Elite Club, Shahreza Branch, Islamic Azad University, Shahreza (Iran, Islamic Republic of); Nezamzadeh-Ejhieh, Alireza, E-mail: arnezamzadeh@iaush.ac.ir [Department of Chemistry, Shahreza Branch, Islamic Azad University, P.O. Box 311-86145, Shahreza, Isfahan (Iran, Islamic Republic of); Young Researchers and Elite Club, Shahreza Branch, Islamic Azad University, Shahreza (Iran, Islamic Republic of); Razi Chemistry Research Center (RCRC), Shahreza Branch, Islamic Azad University, Isfahan (Iran, Islamic Republic of)

    2016-11-15

    Highlights: • Increase in photocatalytic activity of hybridized/supported PbO/NiO and PbS/NiS systems with respect to semiconductors alone. • Higher efficiency of PbO/NiO than PbS/NiS. • Positive role of p-n junction for enhancement of photocatalytic activity of the used semiconductors. - Abstract: The Ni(II)-Pb(II) exchanged clinoptilolite nanoparticles (NCP) were transformed to corresponding oxides and sulfides via calcination and sulfiding processes, respectively. The obtained catalysts were characterized by XRD, FT-IR, TEM and DRS and used in photodegradation of p-nitrophenol (4-NP) aqueous solution under Hg-lamp irradiation. Results showed considerable increase in activity of the coupled semiconductors with respect to monocomponent one. In NiO-PbO-NCP system, conduction band (CB) of NiO is enough negative for easily migration of photogenerated electrons to CB-PbO level, while such phenomena take place from more negative CB-PbS level to CB-NiS level in NiS-PbS-NCP. These phenomena significantly prevented from electron-hole recombination which increased photocatalytic activity of the coupled semiconductors. Best photodegradation activities obtained by NiO{sub 1.3%}–PbO{sub 14.7%}-NCP and NiS{sub 2.1%}–PbS{sub 10.0%}-NCP, confirming semiconductors' mass-ratio dependence of the photocatalytic process. The supported coupled semiconductors showed blue shifts in band gap energies with respect to the bulk semiconductors which confirm formation of semiconductors nanoparticles inside the zeolite framework. The highest degradation percentage of 4-NP was obtained at: 0.5 g L{sup −1} photocatalysts, 15 mg L{sup −1} 4-NP at pH 7.5.

  20. A Quantitative Diffuse Reflectance Imaging (QDRI) System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins.

    Science.gov (United States)

    Nichols, Brandon S; Schindler, Christine E; Brown, Jonathon Q; Wilke, Lee G; Mulvey, Christine S; Krieger, Marlee S; Gallagher, Jennifer; Geradts, Joseph; Greenup, Rachel A; Von Windheim, Jesko A; Ramanujam, Nirmala

    2015-01-01

    In an ongoing effort to address the clear clinical unmet needs surrounding breast conserving surgery (BCS), our group has developed a next-generation multiplexed optical-fiber-based tool to assess breast tumor margin status during initial surgeries. Specifically detailed in this work is the performance and clinical validation of a research-grade intra-operative tool for margin assessment based on diffuse optical spectroscopy. Previous work published by our group has illustrated the proof-of-concept generations of this device; here we incorporate a highly optimized quantitative diffuse reflectance imaging (QDRI) system utilizing a wide-field (imaging area = 17 cm(2)) 49-channel multiplexed fiber optic probe, a custom raster-scanning imaging platform, a custom dual-channel white LED source, and an astronomy grade imaging CCD and spectrograph. The system signal to noise ratio (SNR) was found to be greater than 40 dB for all channels. Optical property estimation error was found to be less than 10%, on average, over a wide range of absorption (μa = 0-8.9 cm(-1)) and scattering (μs' = 7.0-9.7 cm(-1)) coefficients. Very low inter-channel and CCD crosstalk was observed (2% max) when used on turbid media (including breast tissue). A raster-scanning mechanism was developed to achieve sub-pixel resolution and was found to be optimally performed at an upsample factor of 8, affording 0.75 mm spatially resolved diffuse reflectance images (λ = 450-600 nm) of an entire margin (area = 17 cm(2)) in 13.8 minutes (1.23 cm(2)/min). Moreover, controlled pressure application at the probe-tissue interface afforded by the imaging platform reduces repeated scan variability, providing operative time scales with improved sensitivity to regions of focal disease that may otherwise be overlooked.

  1. Organization A Comprehensive System Of Insurance Coverage In The Potential Chemical And Biological Contamination Zone In Regions

    Directory of Open Access Journals (Sweden)

    Nina Vladimirovna Zaytseva

    2014-12-01

    Full Text Available The article provides a scientific rationale for an integrated approach to the provision of insurance coverage in the potential chemical and biological contamination zone. The following modern forms of chemical safety in the Russian Federation were considered: state reserve’s system, target program financing, state social insurance. The separate issue tackles the obligatory civil liability insurance for owners of dangerous objects. For improvement of the existing insurance protection system against emergency situations, risks were analyzed (shared on exogenous and endogenous. Among the exogenous risks including natural and climatic conditions of a region, its geographical arrangement, economic specialization, the seismic and terrorist risks were chosen and approaches to its solution were suggested. In endogenous risks’ group, the special focus is on wear and tear and obsolescence of hazardous chemical and biological object’s fixed assets. In case of high risk of an incident, it is suggested to increase in extent of insurance protection through self-insurance, a mutual insurance in the form of the organization of societies of a mutual insurance or the self-regulating organizations, and also development of voluntary insurance of a civil liability, both the owner of hazardous object, and regions of the Russian Federation and municipalities. The model of insurance coverage in the potential chemical and biological contamination zone is based on a differentiated approach to the danger level of the area. A matrix of adequate forms and types of insurance (required for insurance coverage of the population in the potential chemical and biological contamination zone was constructed. Proposed health risk management toolkit in the potential chemical and biological contamination zone will allow to use financial resources for chemical and biological safety in the regions more efficiently.

  2. Energy Return on Energy Invested (ERoEI) for photovoltaic solar systems in regions of moderate insolation: A comprehensive response

    International Nuclear Information System (INIS)

    Raugei, Marco; Sgouridis, Sgouris; Murphy, David; Fthenakis, Vasilis; Frischknecht, Rolf; Breyer, Christian; Bardi, Ugo; Barnhart, Charles; Buckley, Alastair; Carbajales-Dale, Michael; Csala, Denes; Wild-Scholten, Mariska de; Heath, Garvin; Jæger-Waldau, Arnulf; Jones, Christopher; Keller, Arthur; Leccisi, Enrica; Mancarella, Pierluigi

    2017-01-01

    A recent paper by asserts that the ERoEI (also referred to as EROI) of photovoltaic (PV) systems is so low that they actually act as net energy sinks, rather than delivering energy to society. Such claim, if accurate, would call into question many energy investment decisions. In the same paper, a comparison is also drawn between PV and nuclear electricity. We have carefully analysed this paper, and found methodological inconsistencies and calculation errors that, in combination, render its conclusions not scientifically sound. Ferroni and Hopkirk adopt ‘extended’ boundaries for their analysis of PV without acknowledging that such choice of boundaries makes their results incompatible with those for all other technologies that have been analysed using more conventional boundaries, including nuclear energy with which the authors engage in multiple inconsistent comparisons. In addition, they use out-dated information, make invalid assumptions on PV specifications and other key parameters, and conduct calculation errors, including double counting. We herein provide revised EROI calculations for PV electricity in Switzerland, adopting both conventional and ‘extended’ system boundaries, to contrast with their results, which points to an order-of-magnitude underestimate of the EROI of PV in Switzerland by Ferroni and Hopkirk. - Highlights: • A recent paper by Ferroni and Hopkirk estimated an EROI=0.8 for PV in Switzerland. • We identify several critical methodological and calculation flaws in that paper. • We discuss such flaws in detail and rebut Ferroni and Hopkirk's conclusions. • We provide revised EROI calculations with both conventional and extended boundaries.

  3. Comprehensive overview of prostatitis.

    Science.gov (United States)

    Khan, Farhan Ullah; Ihsan, Awais Ullah; Khan, Hidayat Ullah; Jana, Ruby; Wazir, Junaid; Khongorzul, Puregmaa; Waqar, Muhammad; Zhou, Xiaohui

    2017-10-01

    Prostatitis is a common urinary tract syndrome that many doctors find problematic to treat effectively. It is the third most commonly found urinary tract disease in men after prostate cancer and Benign Prostate Hyperplasia (BPH). Prostatitis may account for 25% of all office visits made to the urological clinics complaining about the genital and urinary systems all over the world. In the present study, we classified prostatitis and comprehensively elaborated the etiology, pathogenesis, diagnosis, and treatment of acute bacterial prostatitis (category I), chronic bacterial prostatitis (category II), chronic pelvic pain syndrome (CPPS) (category III), and asymptomatic prostatitis (category IV). In addition, we also tried to get some insights about other types of prostatitis-like fungal, viral and gonococcal prostatitis. The aim of this review is to present the detail current perspective of prostatitis in a single review. To the best of our knowledge currently, there is not a single comprehensive review, which can completely elaborate this important topic in an effective way. Furthermore, this review will provide a solid platform to conduct future studies on different aspects such as risk factors, mechanism of pathogenesis, proper diagnosis, and rational treatment plans for fungal, viral, and gonococcal prostatitis. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  4. Comprehensive national energy strategy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    This Comprehensive National Energy Strategy sets forth a set of five common sense goals for national energy policy: (1) improve the efficiency of the energy system, (2) ensure against energy disruptions, (3) promote energy production and use in ways that respect health and environmental values, (4) expand future energy choices, and (5) cooperate internationally on global issues. These goals are further elaborated by a series of objectives and strategies to illustrate how the goals will be achieved. Taken together, the goals, objectives, and strategies form a blueprint for the specific programs, projects, initiatives, investments, and other actions that will be developed and undertaken by the Federal Government, with significant emphasis on the importance of the scientific and technological advancements that will allow implementation of this Comprehensive National Energy Strategy. Moreover, the statutory requirement of regular submissions of national energy policy plans ensures that this framework can be modified to reflect evolving conditions, such as better knowledge of our surroundings, changes in energy markets, and advances in technology. This Strategy, then, should be thought of as a living document. Finally, this plan benefited from the comments and suggestions of numerous individuals and organizations, both inside and outside of government. The Summary of Public Comments, located at the end of this document, describes the public participation process and summarizes the comments that were received. 8 figs.

  5. A Quantitative Diffuse Reflectance Imaging (QDRI System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins.

    Directory of Open Access Journals (Sweden)

    Brandon S Nichols

    Full Text Available In an ongoing effort to address the clear clinical unmet needs surrounding breast conserving surgery (BCS, our group has developed a next-generation multiplexed optical-fiber-based tool to assess breast tumor margin status during initial surgeries. Specifically detailed in this work is the performance and clinical validation of a research-grade intra-operative tool for margin assessment based on diffuse optical spectroscopy. Previous work published by our group has illustrated the proof-of-concept generations of this device; here we incorporate a highly optimized quantitative diffuse reflectance imaging (QDRI system utilizing a wide-field (imaging area = 17 cm(2 49-channel multiplexed fiber optic probe, a custom raster-scanning imaging platform, a custom dual-channel white LED source, and an astronomy grade imaging CCD and spectrograph. The system signal to noise ratio (SNR was found to be greater than 40 dB for all channels. Optical property estimation error was found to be less than 10%, on average, over a wide range of absorption (μa = 0-8.9 cm(-1 and scattering (μs' = 7.0-9.7 cm(-1 coefficients. Very low inter-channel and CCD crosstalk was observed (2% max when used on turbid media (including breast tissue. A raster-scanning mechanism was developed to achieve sub-pixel resolution and was found to be optimally performed at an upsample factor of 8, affording 0.75 mm spatially resolved diffuse reflectance images (λ = 450-600 nm of an entire margin (area = 17 cm(2 in 13.8 minutes (1.23 cm(2/min. Moreover, controlled pressure application at the probe-tissue interface afforded by the imaging platform reduces repeated scan variability, providing <1% variation across repeated scans of clinical specimens. We demonstrate the clinical utility of this device through a pilot 20-patient study of high-resolution optical parameter maps of the ratio of the β-carotene concentration to the reduced scattering coefficient. An empirical cumulative

  6. Comprehensive Study of All-Solid-State Z-Scheme Photocatalytic Systems of ZnO/Pt/CdZnS

    KAUST Repository

    Isimjan, Tayirjan Taylor

    2017-08-22

    We have investigated a Z-scheme based on a ZnO/Pt/CdZnS photocatalyst, active in the presence of a complex medium composed of acetic acid and benzyl alcohol, the effects of which on the catalyst stability and performance are studied. Transmission electron microscopy images showed uniformly dispersed sub-nanometer Pt particles. Inductively coupled plasma and X-ray photoelectron spectroscopy analyses suggested that Pt is sandwiched between ZnO and CdZnS. An apparent quantum yield (AQY) of 34% was obtained over the [ZnO]4/1 wt %Pt/CdZnS system at 360 nm, 2.5-fold higher than that of 1%Pt/CdZnS (14%). Furthermore, an AQY of 16% was observed using [ZnO]4/1 wt %Pt/CdZnS, which was comparable to that of 1 wt %Pt/CdZnS (10%) at 460 nm. On the basis of these results, we proposed a charge transfer mechanism, which was confirmed through femtosecond transient absorption spectroscopy. Finally, we identified the two main factors that affected the stability of the catalyst, which were the sacrificial reagent and the acidic pH.

  7. Optimization and comprehensive characterization of metal hydride based hydrogen storage systems using in-situ Neutron Radiography

    Science.gov (United States)

    Börries, S.; Metz, O.; Pranzas, P. K.; Bellosta von Colbe, J. M.; Bücherl, T.; Dornheim, M.; Klassen, T.; Schreyer, A.

    2016-10-01

    For the storage of hydrogen, complex metal hydrides are considered as highly promising with respect to capacity, reversibility and safety. The optimization of corresponding storage tanks demands a precise and time-resolved investigation of the hydrogen distribution in scaled-up metal hydride beds. In this study it is shown that in situ fission Neutron Radiography provides unique insights into the spatial distribution of hydrogen even for scaled-up compacts and therewith enables a direct study of hydrogen storage tanks. A technique is introduced for the precise quantification of both time-resolved data and a priori material distribution, allowing inter alia for an optimization of compacts manufacturing process. For the first time, several macroscopic fields are combined which elucidates the great potential of Neutron Imaging for investigations of metal hydrides by going further than solely 'imaging' the system: A combination of in-situ Neutron Radiography, IR-Thermography and thermodynamic quantities can reveal the interdependency of different driving forces for a scaled-up sodium alanate pellet by means of a multi-correlation analysis. A decisive and time-resolved, complex influence of material packing density is derived. The results of this study enable a variety of new investigation possibilities that provide essential information on the optimization of future hydrogen storage tanks.

  8. Development of RODOS, a comprehensive real-time on-line decision support system for nuclear emergency management in Europe. Final report

    International Nuclear Information System (INIS)

    Ehrhardt, J.; Weis, A.

    1996-09-01

    The development of RODOS, a comprehensive, Real-time, On-line DecisiOn Support system for nuclear emergency management, that would be capable of finding broad application across Europe was included as a major item in the Radiation Protection Research Action of the European Commission's 3rd Framework Programme; it remains an important priority in the 4th Framework programme (1995-1998). When complete, the RODOS system is intended to be applicable from the vicinity of the release and the early phases of an accident to far distant areas and longer time periods. In this way it will be possible to achieve estimates, analyses, and prognoses of accident consequences with and without considering protective actions and countermeasures, which are consistent throughout all accident phases and distance ranges. It will also be possible to evaluate alternative combinations of measures in term of both, feasibility in the given situation, and public acceptability, socio-psychological and political implications. This Final Report summarises the results achieved by the partners of the EC contract FI3P-CT92-0036 within the time period 1992 to 1995, and more generally, gives an overview of the development status of the RODOS system and its functionalities realised by the end of the contract period. (orig.) [de

  9. Design of A Vibration and Stress Measurement System for an Advanced Power Reactor 1400 Reactor Vessel Internals Comprehensive Vibration Assessment Program

    International Nuclear Information System (INIS)

    Ko, Doyoung; Kim, Kyuhyung

    2013-01-01

    In accordance with the US Nuclear Regulatory Commission (US NRC), Regulatory Guide 1.20, the reactor vessel internals comprehensive vibration assessment program (RVI CVAP) has been developed for an Advanced Power Reactor 1400 (APR1400). The purpose of the RVI CVAP is to verify the structural integrity of the reactor internals to flow-induced loads prior to commercial operation. The APR1400 RVI CVAP consists of four programs (analysis, measurement, inspection, and assessment). Thoughtful preparation is essential to the measurement program, because data acquisition must be performed only once. The optimized design of a vibration and stress measurement system for the RVI CVAP is essential to verify the integrity of the APR1400 RVI. We successfully designed a vibration and stress measurement system for the APR1400 RVI CVAP based on the design materials, the hydraulic and structural analysis results, and performance tests of transducers in an extreme environment. The measurement system designed in this paper will be utilized for the APR1400 RVI CVAP as part of the first construction project in Korea

  10. DESIGN OF A VIBRATION AND STRESS MEASUREMENT SYSTEM FOR AN ADVANCED POWER REACTOR 1400 REACTOR VESSEL INTERNALS COMPREHENSIVE VIBRATION ASSESSMENT PROGRAM

    Directory of Open Access Journals (Sweden)

    DO-YOUNG KO

    2013-04-01

    Full Text Available In accordance with the US Nuclear Regulatory Commission (US NRC, Regulatory Guide 1.20, the reactor vessel internals comprehensive vibration assessment program (RVI CVAP has been developed for an Advanced Power Reactor 1400 (APR1400. The purpose of the RVI CVAP is to verify the structural integrity of the reactor internals to flow-induced loads prior to commercial operation. The APR1400 RVI CVAP consists of four programs (analysis, measurement, inspection, and assessment. Thoughtful preparation is essential to the measurement program, because data acquisition must be performed only once. The optimized design of a vibration and stress measurement system for the RVI CVAP is essential to verify the integrity of the APR1400 RVI. We successfully designed a vibration and stress measurement system for the APR1400 RVI CVAP based on the design materials, the hydraulic and structural analysis results, and performance tests of transducers in an extreme environment. The measurement system designed in this paper will be utilized for the APR1400 RVI CVAP as part of the first construction project in Korea.

  11. Best practices and better protocols : guidance for a comprehensive community emissions inventory system from a high level review of international best practices

    International Nuclear Information System (INIS)

    Boston, A.

    2007-11-01

    A community greenhouse gas emission and energy inventory is an important tool to help local governments plan, implement and monitor climate change mitigation strategies and sustainable energy systems. Inventories can also facilitate a number of other local priorities such as air quality management; integrated land-use and transportation planning; infrastructure optimization and planning; and community economic development planning. The British Columbia government's community energy and emissions inventory initiative (CEEI) intends to collect and centralize high-quality geocoded data to generate high-value community inventories for the province's 185 local governments. This report presented strategic guidance for a comprehensive community emissions inventory system based on a high level review of international best practices. The report described the project objective and scope; guiding principles; research methodology; and inventory limitations. The report provided observations, findings and recommendations according to the following four areas: protocols and standards recommendations; data management systems recommendations; community inventory parameters recommendations; and reporting formats and capacity building recommendations. It was recommended that as CEEI progresses, consideration should be given to developing provincial level reports and online reporting of local government activity in order to strengthen awareness, recognize leadership and build support.17 refs., 2 tabs., 11 figs., 2 appendices

  12. Multi-Objective Sustainable Operation of the Three Gorges Cascaded Hydropower System Using Multi-Swarm Comprehensive Learning Particle Swarm Optimization

    Directory of Open Access Journals (Sweden)

    Xiang Yu

    2016-06-01

    Full Text Available Optimal operation of hydropower reservoir systems often needs to optimize multiple conflicting objectives simultaneously. The conflicting objectives result in a Pareto front, which is a set of non-dominated solutions. Non-dominated solutions cannot outperform each other on all the objectives. An optimization framework based on the multi-swarm comprehensive learning particle swarm optimization algorithm is proposed to solve the multi-objective operation of hydropower reservoir systems. Through adopting search techniques such as decomposition, mutation and differential evolution, the algorithm tries to derive multiple non-dominated solutions reasonably distributed over the true Pareto front in one single run, thereby facilitating determining the final tradeoff. The long-term sustainable planning of the Three Gorges cascaded hydropower system consisting of the Three Gorges Dam and Gezhouba Dam located on the Yangtze River in China is studied. Two conflicting objectives, i.e., maximizing hydropower generation and minimizing deviation from the outflow lower target to realize the system’s economic, environmental and social benefits during the drought season, are optimized simultaneously. Experimental results demonstrate that the optimization framework helps to robustly derive multiple feasible non-dominated solutions with satisfactory convergence, diversity and extremity in one single run for the case studied.

  13. Towards a contemporary, comprehensive scoring system for determining technical outcomes of hybrid percutaneous chronic total occlusion treatment: The RECHARGE score.

    Science.gov (United States)

    Maeremans, Joren; Spratt, James C; Knaapen, Paul; Walsh, Simon; Agostoni, Pierfrancesco; Wilson, William; Avran, Alexandre; Faurie, Benjamin; Bressollette, Erwan; Kayaert, Peter; Bagnall, Alan J; Smith, Dave; McEntegart, Margaret B; Smith, William H T; Kelly, Paul; Irving, John; Smith, Elliot J; Strange, Julian W; Dens, Jo

    2018-02-01

    This study sought to create a contemporary scoring tool to predict technical outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) from patients treated by hybrid operators with differing experience levels. Current scoring systems need regular updating to cope with the positive evolutions regarding materials, techniques, and outcomes, while at the same time being applicable for a broad range of operators. Clinical and angiographic characteristics from 880 CTO-PCIs included in the REgistry of CrossBoss and Hybrid procedures in FrAnce, the NetheRlands, BelGium and UnitEd Kingdom (RECHARGE) were analyzed by using a derivation and validation set (2:1 ratio). Variables significantly associated with technical failure in the multivariable analysis were incorporated in the score. Subsequently, the discriminatory capacity was assessed and the validation set was used to compare with the J-CTO score and PROGRESS scores. Technical success in the derivation and validation sets was 83% and 85%, respectively. Multivariate analysis identified six parameters associated with technical failure: blunt stump (beta coefficient (b) = 1.014); calcification (b = 0.908); tortuosity ≥45° (b = 0.964); lesion length 20 mm (b = 0.556); diseased distal landing zone (b = 0.794), and previous bypass graft on CTO vessel (b = 0.833). Score variables remained significant after bootstrapping. The RECHARGE score showed better discriminatory capacity in both sets (area-under-the-curve (AUC) = 0.783 and 0.711), compared to the J-CTO (AUC = 0.676) and PROGRESS (AUC = 0.608) scores. The RECHARGE score is a novel, easy-to-use tool for assessing the risk for technical failure in hybrid CTO-PCI and has the potential to perform well for a broad community of operators. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  14. Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

    Science.gov (United States)

    Tsang-A-Sjoe, M W P; Bultink, I E M; Korswagen, L A; van der Horst, A; Rensink, I; de Boer, M; Hamann, D; Voskuyl, A E; Wouters, D

    2017-12-01

    Genetic variation of the genes encoding complement component C4 is strongly associated with systemic lupus erythematosus (SLE), a chronic multi-organ auto-immune disease. This study examined C4 and its isotypes on a genetic, protein, and functional level in 140 SLE patients and 104 healthy controls. Gene copy number (GCN) variation, silencing CT-insertion, and the retroviral HERV-K(C4) insertion) were analyzed with multiplex ligation-dependent probe amplification. Increased susceptibility to SLE was found for low GCN (≪2) of C4A. Serositis was the only clinical manifestation associated with low C4A GCN. One additional novel silencing mutation in the C4A gene was found by Sanger sequencing. This mutation causes a premature stop codon in exon 11. Protein concentrations of C4 isoforms C4A and C4B were determined with ELISA and were significantly lower in SLE patients compared to healthy controls. To study C4 isotypes on a functional level, a new C4 assay was developed, which distinguishes C4A from C4B by its binding capacity to amino or hydroxyl groups, respectively. This assay showed high correlation with ELISA and detected crossing over of Rodgers and Chido antigens in 3.2% (8/244) of individuals. The binding capacity of available C4 to its substrates was unaffected in SLE. Our study provides, for the first time, a complete overview of C4 in SLE from genetic variation to binding capacity using a novel test. As this test detects crossing over of Rodgers and Chido antigens, it will allow for more accurate measurement of C4 in future studies. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. A fundamental tax reform in Norway : a comparison of the allowance for corporate equity system and the comprehensive business income tax system in a Norwegian setting

    OpenAIRE

    Riskjell, Ole Kristian

    2014-01-01

    This thesis seeks to answer what are the main distortions in the Norwegian tax system and to determine which of the ACE or CBIT systems that best could replace the current system. First, the thesis considers the current distortions in the Norwegian tax system. I find that the current tax system is distortive with regards to the tax-treatment of debt versus equity, as only cost of debt is deductible for tax purposes, while cost of equity is not. Moreover, the current system is d...

  16. Usability and feasibility of a mobile health system to provide comprehensive antenatal care in low-income countries: PANDA mHealth pilot study in Madagascar.

    Science.gov (United States)

    Benski, Anne Caroline; Stancanelli, Giovanna; Scaringella, Stefano; Herinainasolo, Josea Léa; Jinoro, Jéromine; Vassilakos, Pierre; Petignat, Patrick; Schmidt, Nicole C

    2017-06-01

    Background Madagascar's maternal health mortality ratio in 2013 was 478 deaths per 100,000 live births. Most deaths are related to direct complications during pregnancy and childbirth and could be reduced by providing comprehensive antenatal care (ANC). Objective The objective of the study was to assess the usability and feasibility of a mobile health system (mHealth) to provide high-quality ANC, according to World Health Organization (WHO) recommendations. Methods PANDA (Pregnancy And Newborn Diagnostic Assessment) is an easy-to-use mHealth system that uses affordable communications technology to support diagnosis and health care worker decision-making regarding ANC. From January to March 2015, a cross-sectional pilot study was conducted in Ambanja District, Madagascar, in which ANC using PANDA was provided to 100 pregnant women. The collected data were transmitted to a database in the referral hospital to create individual electronic patient records. Accuracy and completeness of the data were closely controlled. The PANDA software was assessed and the number of abnormal results, treatments performed, and participants requiring referral to health care facilities were monitored. Results The PANDA system facilitated creation of individual electronic patient records that included socio-demographic and medical data for 100 participants. Duration of ANC visits averaged 29.6 min. Health care providers were able to collect all variables (100%) describing personal and medical data. No major technical problems were encountered and no data were lost. During 17 ANC visits (17%), an alert function was generated to highlight abnormal clinical results requiring therapy or referral to an affiliated hospital. Participants' acceptability of the system was very high. Conclusion This pilot study proved the usability and feasibility of the PANDA mHealth system to conduct complete and standardised ANC visits according to WHO guidelines, thus providing a promising solution to

  17. Comparison of the efficacy of biologics versus conventional systemic therapies in the treatment of psoriasis at a comprehensive psoriasis care center.

    Science.gov (United States)

    Au, Shiu-Chung; Madani, Abdulaziz; Alhaddad, Marwan; Alkofide, Maha; Gottlieb, Alice B

    2013-08-01

    The efficacy of biologic treatment for psoriasis has not been compared to that of conventional systemic therapies and phototherapy outside of clinical trial settings. Retrospective, cross-sectional. All patient visits with a code for psoriasis (ICD-9 696.1) in the clinical practice of two dermatologists with a high percentage (over 70% of chief complaints) of psoriasis patients from Jan 1, 2008 to Jan 4, 2012 inclusive were included in this retrospective data analysis. Patients were excluded if the baseline Physician's Global Assessment (PGA) at start of treatment was unknown, or less than 3 (moderate). The practice is a comprehensive psoriasis care center in the Northeastern United States serving a metropolitan population of over 4 million people. Patients were divided by treatment type (biologic, conventional systemic or both) and history of previous treatments. Patients were evaluated by Body Surface Area (BSA), PGA, Simple-Measure for Assessing Psoriasis Activity (S-MAPA, calculated by BSA multiplied by PGA). Patients were evaluated at baseline, 8, 12, 16, and 24 weeks after start of treatment. Patients must have completed at least 8 weeks on a single treatment in order to be included. 46 courses of biologics, 12 courses of conventional systemic therapies, and 18 courses of both together were identified with PGA 3 or greater at baseline. Baseline S-MAPA for biologics was 74, for non-biologic systemics was 62.25. At week 24, S-MAPA improved 70.2% over baseline in patients treated with biologics, patients treated with non-biologic systemics improved by only 40.4% (PMAPA (PGA multiplied by BSA) at week 24. These results were observed despite the fact that patients on biologics had a greater baseline severity and had a greater number of previous treatments.

  18. Lateralisation effect in comprehension of emotional facial expression: a comparison between EEG alpha band power and behavioural inhibition (BIS) and activation (BAS) systems.

    Science.gov (United States)

    Balconi, Michela; Mazza, Guido

    2010-05-01

    Asymmetry in comprehension of facial expression of emotions was explored in the present study by analysing alpha band variation within the right and left cortical sides. Second, the behavioural activation system (BAS) and behavioural inhibition system (BIS) were considered as an explicative factor to verify the effect of a motivational/emotional variable on alpha activity. A total of 19 participants looked at an ample range of facial expressions of emotions (anger, fear, surprise, disgust, happiness, sadness, and neutral) in random order. The results demonstrated that anterior frontal sites were more active than central and parietal sites in response to facial stimuli. Moreover, right and left side responses varied as a function of emotional types, with an increased right frontal activity for negative, aversive emotions vs an increased left response for positive emotion. Finally, whereas higher BIS participants generated more right hemisphere activation for some negative emotions (such as fear, anger, surprise, and disgust), BAS participants were more responsive to positive emotion (happiness) within the left hemisphere. Motivational significance of facial expressions was considered to elucidate cortical differences in participants' responses to emotional types.

  19. A mobile system for a comprehensive online-characterization of nanoparticle aggregates based on wide-angle light scattering and laser-induced incandescence

    Energy Technology Data Exchange (ETDEWEB)

    Huber, Franz J. T.; Will, Stefan, E-mail: stefan.will@fau.de [Lehrstuhl für Technische Thermodynamik (LTT), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen 91058 (Germany); Erlangen Graduate School in Advanced Optical Technologies (SAOT), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen 91052 (Germany); Cluster of Excellence Engineering of Advanced Materials (EAM), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen 91052 (Germany); Altenhoff, Michael [Lehrstuhl für Technische Thermodynamik (LTT), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen 91058 (Germany); Erlangen Graduate School in Advanced Optical Technologies (SAOT), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen 91052 (Germany)

    2016-05-15

    A mobile demonstrator for the comprehensive online-characterization of gas-borne nanoparticle aggregates is presented. Two optical measurement techniques are combined, both utilizing a pulsed Nd:YAG laser as light source. Aggregate size and fractal dimension are measured by Wide-Angle Light Scattering (WALS). An ellipsoidal mirror images elastically scattered light from scattering angles between 10° and 165° onto a CCD-camera chip resulting in an almost complete scattering diagram with high angular resolution. Primary particle size and volume fraction are measured by time-resolved Laser-Induced Incandescence (TiRe-LII). Here, particles are heated up to about 3000 K by the short laser pulse, the enhanced thermal radiation signal is detected with gated photomultiplier tubes. Analysis of the signal decay time and maximum LII-signal allows for the determination of primary particle diameter and volume fraction. The performance of the system is demonstrated by combined measurements on soot nanoparticle aggregates from a soot aerosol generator. Particle and aggregate sizes are varied by using different equivalence ratios of the combustion in the generator. Soot volume fraction can be adjusted by different levels of dilution with air. Online-measurements were carried out demonstrating the favorable performance of the system and the potential for industrial applications such as process control and product development. The particle properties obtained are confirmed through transmission electron microscopy analysis on representative samples.

  20. A case study of translating ACGME practice-based learning and improvement requirements into reality: systems quality improvement projects as the key component to a comprehensive curriculum.

    Science.gov (United States)

    Tomolo, A M; Lawrence, R H; Aron, D C

    2009-10-01

    In 2002, the Accreditation Council for Graduate Medical Education (ACGME) introduced a new requirement: residents must demonstrate competency in Practice-Based Learning and Improvement (PBLI). Training in this domain is still not consistently integrated into programmes, with few, if any, adequately going beyond knowledge of basic content and addressing all components of the requirement. To summarise the implementation of a PBLI curriculum designed to address all components of the requirement and to evaluate the impact on the practice system. A case-study approach was used for identifying and evaluating the steps for delivering the curriculum, along with the Model for Improvement's successive Plan-Do-Study-Act (PDSA) cycles (July 2004-May 2006). Notes from curriculum development meetings, notes and presentation slides made by teams about their projects, resident curriculum exit evaluations curriculum and interviews. Residents reported high levels of comfort by applying PBLI-related knowledge and skills and that the curriculum improved their ability to do various PBLI tasks. The involvement of multiple stakeholders increased. Twelve of the 15 teams' suggestions with practical systems-relevant outcomes were implemented and sustained beyond residents' project periods. While using the traditional PDSA cycles was helpful, there were limitations. A PBLI curriculum that is centred around practice-based quality improvement projects can fulfil the objectives of this ACGME competency while accomplishing sustained outcomes in quality improvement. A comprehensive curriculum is an investment but offers organisational rewards. We propose a more realistic and informative representation of rapid PDSA cycle changes.

  1. A mobile system for a comprehensive online-characterization of nanoparticle aggregates based on wide-angle light scattering and laser-induced incandescence

    International Nuclear Information System (INIS)

    Huber, Franz J. T.; Will, Stefan; Altenhoff, Michael

    2016-01-01

    A mobile demonstrator for the comprehensive online-characterization of gas-borne nanoparticle aggregates is presented. Two optical measurement techniques are combined, both utilizing a pulsed Nd:YAG laser as light source. Aggregate size and fractal dimension are measured by Wide-Angle Light Scattering (WALS). An ellipsoidal mirror images elastically scattered light from scattering angles between 10° and 165° onto a CCD-camera chip resulting in an almost complete scattering diagram with high angular resolution. Primary particle size and volume fraction are measured by time-resolved Laser-Induced Incandescence (TiRe-LII). Here, particles are heated up to about 3000 K by the short laser pulse, the enhanced thermal radiation signal is detected with gated photomultiplier tubes. Analysis of the signal decay time and maximum LII-signal allows for the determination of primary particle diameter and volume fraction. The performance of the system is demonstrated by combined measurements on soot nanoparticle aggregates from a soot aerosol generator. Particle and aggregate sizes are varied by using different equivalence ratios of the combustion in the generator. Soot volume fraction can be adjusted by different levels of dilution with air. Online-measurements were carried out demonstrating the favorable performance of the system and the potential for industrial applications such as process control and product development. The particle properties obtained are confirmed through transmission electron microscopy analysis on representative samples.

  2. Comprehensive dictionary of electrical engineering

    CERN Document Server

    Laplante, Philip A

    1998-01-01

    The Comprehensive Dictionary of Electrical Engineering is a complete lexicon covering all the fields of electrical engineering.Areas examined include:applied electrical engineeringmicrowave engineeringcontrol engineeringpower engineeringdigital systems engineeringdevice electronicsand much more! The book provides workable definitions for practicing engineers, serves as a reference and research tool for students, and offers practical information for scientists and engineers in other disciplines.

  3. Management of Holding and Evaluating Comprehensive System of Electronic Clinical Reasoning Exams (Sajab in the Sixth Nationwide Medical Sciences Students Olympiad

    Directory of Open Access Journals (Sweden)

    Manouchehr Khoshbaten

    2015-12-01

    Full Text Available Introduction: The Nationwide Medical Sciences Students purpose of the Olympiad is to discover student’s talents and encourage them to study. It seems that holding regional Olympiad exams to select students for the National Olympiad can help us to maintain fairness. The aim of this study is Management of Holding and Evaluating Clinical Reasoning Exams Using a Comprehensive System of Electronic Clinical Reasoning Exams. Methods: Study was carried out in 2013 at the University of Medical Sciences on 750 students, 250 question designers, 37 responsibles. The nationwide universities held regional exams for the Student Olympiad in the area of clinical reasoning on specific dates and times. A quality review of the exams was done to study the strengths and weaknesses and to eliminate shortcomings and problems. Therefore, a researcher created a questionnaire with a reliability of R= 0.86 and validity was confirmed by experts, which was then loaded into the system. The collected data were analyzed using SPSS and descriptive statistics (Percent, Average, standard deviation. Results: The multimedia educational quality of the system, with an average of 69.36 ±22.79, the students and faculty members evaluated as good, with averages of 64.30 ±23.48 and 67.28 ± 22.43, respectively. The quality of the exam was evaluated as excellent by faculty members, with an average of 94.63 ±16.60 and 59.52 ±27.46, by the students. Conclusion: Evaluating the quality of the system’s performance and its ability to assess students will lead to a clarification of its strengths and weaknesses. Finally, result in the creation of a high quality evaluation system.

  4. Comprehensive genotyping for 18 blood group systems using a multiplex ligation-dependent probe amplification assay shows a high degree of accuracy

    NARCIS (Netherlands)

    Haer-Wigman, Lonneke; Ji, Yanli; Lodén, Martin; de Haas, Masja; van der Schoot, C. Ellen; Veldhuisen, Barbera

    2013-01-01

    In recent years genotyping methods have been implemented in blood banks as alternative to comprehensive serologic typing. We evaluated a newly developed assay for convenient and comprehensive genotyping of blood group alleles based on multiplex ligation-dependent probe amplification (MLPA)

  5. Report on final evaluation of industrial science and technology research and development system. Comprehensive basic technologies for development of ocean resources. Manganese nodule exploitation system; Kaiyo shigen sogo kiban gijutsu (mangan dankai saiko system). Saishu hyoka hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    Described herein are the final evaluation results of the basic research and development of the system for exploiting manganese nodules as one of ocean resources. A 9-year project was started in the FY 1981 to establish the techniques to efficiently, economically exploit Mn nodules on a commercial basis, which are occurring on deep sea bottoms (4,000 to 6,000 m deep), in order to stably supply non-ferrous metallic resources, e.g., Ni, Cu, Co and Mn, which are essential for economic activities of Japan. Originally, the UN convention related to ocean laws raised development of unique exploitation techniques as the prerequisite condition for obtaining the right to develop Mn nodules. However, the situations around development of Mn nodules were changed since then, to devalue objects, significance and urgency of this project. The fourth amendment of the basic plans decided to suspend the comprehensive ocean tests in 1996, and to implement only the ocean/land tests in which part of the individual elementary techniques were combined. Therefore, the technological validation of the overall system could not be done sufficiently, and degree of achievement of the project is low, viewed from insufficient prospects of the commercial production. However, this project produced good results in individual elementary techniques, which are of significance for the resources policies. (NEDO)

  6. Towards a comprehensive understanding of emerging dynamics and function of pancreatic islets: A complex network approach. Comment on "Network science of biological systems at different scales: A review" by Gosak et al.

    Science.gov (United States)

    Loppini, Alessandro

    2018-03-01

    Complex network theory represents a comprehensive mathematical framework to investigate biological systems, ranging from sub-cellular and cellular scales up to large-scale networks describing species interactions and ecological systems. In their exhaustive and comprehensive work [1], Gosak et al. discuss several scenarios in which the network approach was able to uncover general properties and underlying mechanisms of cells organization and regulation, tissue functions and cell/tissue failure in pathology, by the study of chemical reaction networks, structural networks and functional connectivities.

  7. Comprehensive Marine Particle Analysis System

    Science.gov (United States)

    2001-09-30

    Calanoid copepod, B- Poecilostomatoid copepod, C- Centric diatom chain, D- Polychaete, E- Salp , F- Larvacean, G -Hydromedusae, H- Pteropod, I...5 No difference Protoctista 15 321 +2140 Salp and doliolids 31 102 +329 Siphonophores 17 24 +141 Trichodesmium present in low numbers 1958

  8. Creating a Statewide Educational Data System for Accountability and Improvement: A Comprehensive Information and Assessment System for Making Evidence-Based Change at School, District, and Policy Levels

    Science.gov (United States)

    Felner, Robert D.; Bolton, Natalie; Seitsinger, Anne M.; Brand, Stephen; Burns, Amy

    2008-01-01

    This article reports on one ongoing statewide effort to create a high-quality data reporting and utilization system (i.e., High-Performance Learning Community [HiPlaces] Assessment) to inform educational accountability and improvement efforts system. This effort has undergoing refinement for more than a decade. The article describes the features…

  9. Hazard Ranking System evaluation of CERCLA [Comprehensive Environmental Response, Compensation, and Liability Act] inactive waste sites at Hanford: Volume 1, Evaluation methods and results

    International Nuclear Information System (INIS)

    Stenner, R.D.; Cramer, K.H.; Higley, K.A.; Jette, S.J.; Lamar, D.A.; McLaughlin, T.J.; Sherwood, D.R.; Van Houten, N.C.

    1988-10-01

    The purpose of this report is to formally document the individual site Hazard Ranking System (HRS) evaluations conducted as part of the preliminary assessment/site inspection (PA/SI) activities at the US Department of Energy (DOE) Hanford Site. These activities were carried out pursuant to the DOE orders that describe the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Program addressing the cleanup of inactive waste sites. These orders incorporate the US Environmental Protection Agency methodology, which is based on the Superfund Amendments and Reauthorization Act of 1986 (SARA). The methodology includes six parts: PA/SI, remedial investigation/feasibility study, record of decision, design and implementation of remedial action, operation and monitoring, and verification monitoring. Volume 1 of this report discusses the CERCLA inactive waste-site evaluation process, assumptions, and results of the HRS methodology employed. Volume 2 presents the data on the individual CERCLA engineered-facility sites at Hanford, as contained in the Hanford Inactive Site Surveillance (HISS) Data Base. Volume 3 presents the data on the individual CERCLA unplanned-release sites at Hanford, as contained in the HISS Data Base. 34 refs., 43 figs., 47 tabs

  10. Hazard Ranking System evaluation of CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act) inactive waste sites at Hanford: Volume 1, Evaluation methods and results

    Energy Technology Data Exchange (ETDEWEB)

    Stenner, R.D.; Cramer, K.H.; Higley, K.A.; Jette, S.J.; Lamar, D.A.; McLaughlin, T.J.; Sherwood, D.R.; Van Houten, N.C.

    1988-10-01

    The purpose of this report is to formally document the individual site Hazard Ranking System (HRS) evaluations conducted as part of the preliminary assessment/site inspection (PA/SI) activities at the US Department of Energy (DOE) Hanford Site. These activities were carried out pursuant to the DOE orders that describe the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Program addressing the cleanup of inactive waste sites. These orders incorporate the US Environmental Protection Agency methodology, which is based on the Superfund Amendments and Reauthorization Act of 1986 (SARA). The methodology includes six parts: PA/SI, remedial investigation/feasibility study, record of decision, design and implementation of remedial action, operation and monitoring, and verification monitoring. Volume 1 of this report discusses the CERCLA inactive waste-site evaluation process, assumptions, and results of the HRS methodology employed. Volume 2 presents the data on the individual CERCLA engineered-facility sites at Hanford, as contained in the Hanford Inactive Site Surveillance (HISS) Data Base. Volume 3 presents the data on the individual CERCLA unplanned-release sites at Hanford, as contained in the HISS Data Base. 34 refs., 43 figs., 47 tabs.

  11. A comprehensive approach for the simulation of the Urban Heat Island effect with the WRF/SLUCM modeling system: The case of Athens (Greece)

    Science.gov (United States)

    Giannaros, Christos; Nenes, Athanasios; Giannaros, Theodore M.; Kourtidis, Konstantinos; Melas, Dimitrios

    2018-03-01

    This study presents a comprehensive modeling approach for simulating the spatiotemporal distribution of urban air temperatures with a modeling system that includes the Weather Research and Forecasting (WRF) model and the Single-Layer Urban Canopy Model (SLUCM) with a modified treatment of the impervious surface temperature. The model was applied to simulate a 3-day summer heat wave event over the city of Athens, Greece. The simulation, using default SLUCM parameters, is capable of capturing the observed diurnal variation of urban temperatures and the Urban Heat Island (UHI) in the greater Athens Area (GAA), albeit with systematic biases that are prominent during nighttime hours. These biases are particularly evident over low-intensity residential areas, and they are associated with the surface and urban canopy properties representing the urban environment. A series of sensitivity simulations unravels the importance of the sub-grid urban fraction parameter, surface albedo, and street canyon geometry in the overall causation and development of the UHI effect. The sensitivities are then used to determine optimal values of the street canyon geometry, which reproduces the observed temperatures throughout the simulation domain. The optimal parameters, apart from considerably improving model performance (reductions in mean temperature bias from 0.30 °C to 1.58 °C), are also consistent with actual city building characteristics - which gives confidence that the model set-up is robust, and can be used to study the UHI in the GAA in the anticipated warmer conditions in the future.

  12. Coming to grips with negative evidence for the Comprehensive System for the Rorschach: a comment on Gacono, Loving, and Bodholdt; Ganellen; and Bornstein.

    Science.gov (United States)

    Wood, J M; Lilienfeld, S O; Nezworski, M T; Garb, H N

    2001-08-01

    The Comprehensive System (CS; Exner, 1991, 1993) for the Rorschach is currently engulfed in controversy. This comment article responds to 3 articles by Rorschach proponents in this issue of the Journal of Personality Assessment. Contrary to the claims of Gacono, Loving, and Bodholdt (this issue), CS scores do not bear a well-demonstrated relationship to psychopathy, antisocial personality disorder, or conduct disorder. Contrary to the claims of Ganellen (this issue), both the original and the revised CS Depression Index (Exner, 1993) bear little or no relationship to depression diagnoses. Furthermore, the scoring reliability of some CS scores is problematic. Although we agree with Bornstein (this issue) that Rorschach scores generally bear little or no relation to psychiatric diagnoses or self-report questionnaires, we believe this lack of relationship tends to disconfirm hypotheses concerning the validity of the Rorschach. In the spirit of the philosopher Sir Karl Popper, the Rorschach community should not minimize negative evidence or engage in post hoc arguments to immunize the CS against falsification.

  13. Comprehensive Implementation of the International Caries Detection and Assessment System (ICDAS in a Dental School and University Oral Health Centre: A Stepwise Framework

    Directory of Open Access Journals (Sweden)

    Priya Ahlawat

    2014-02-01

    Full Text Available ICDAS (the International Caries Detection and Assessment System is a new approach to the detection and classification of dental caries, starting with the stage showing the earliest visual changes. Methodology: This article describes the implementation of the ICDAS at the School of Dentistry, International Medical University, and Kuala Lumpur, Malaysia in a step-by-step systematically planned process. Beginning with the setting up of a Task Force in 2011 for the evaluation and preparation of the training resources and the running of exploratory training exercises, it finally culminated in carrying out training workshops for the entire staff and students. After the internal processes had been completed, an international expert (KE was invited to evaluate the process and conduct another workshop using the resources developed within the University, including a reference set of carious teeth. The overall time taken was one and a half years. Conclusions: The implementation of the ICDAS has been comprehensively set into motion within the context of our local curriculum and oral healthcare delivery arrangements. However, this will be an ongoing process with further quality assurance measures being required clinically together with the continuing training of new staff. Sharing this ‘framework’ of the ICDAS implementation process should considerably ease the path and reduce the time period of future implementations by other dental teaching institutions.

  14. Evaluation report on research and development of 'the comprehensive water recycling and utilization systems'; 'Mizu sogo saisei riyo system' no kenkyu kaihatsu ni kansuru hyoka hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-08-01

    This research and development project is aimed at treatment of sewage, industrial waste water and the like at lower cost for reutilization, while efficiently producing methane or the like by the systems annexed to the water treatment systems with high-concentration bio-reactor systems incorporating separation membranes. The waste water types studied to be treated by these systems include sewage discharged in large quantities and waste water containing oil/fat and protein (low-concentration waste water), and starch-, alcohol and paper/pulp-containing waste water, and excrements (medium-concentration waste water). The project has found the optimum systems, by adequately configuring the separation membrane modules, and combining dissolution of suspended solid with methane fermentation reactors for selective treatment of organic substances; improved efficiencies of removing organic substances and producing methane by fermentation, and realized reduction in quantities of discharged sludge; and thereby established the bases for the new waste water treatment techniques. The reactor systems developed for water treatment are those based on biological removal of nitrogen. They greatly reduce treatment time to produce treated water of high quality. For treatment of sludge, the techniques have been developed to convert sludge into oil. These results are well applicable to various areas, e.g., sewage treatment, and food and pulp industries. (NEDO)

  15. [Influence of toxin botulin on walk stereotype of children with juvenile cerebral palsy. The functional examination performed by BTS, comprehensive movement analysis system. A preliminary report].

    Science.gov (United States)

    Kwiecień-Czerwieniec, Ilona; Krukowska, Jolanta; Woldańska-Okońska, Marta

    2014-01-01

    Juvenile Cerebral Palsy--is caused by damage of the motor control centers of the developing brain (cerebral refers to the cerebrum, which is the affected area of the brain, although the disorder probably involves connections between the cortex and other parts of the brain and palsy refers to disorder of movement). The clinical symptoms of juvenile cerebral palsy are very diversified and include gross and fine motor-coordination disorders, manual ability, locomotion, perception and response, speech, psychomotor retardation, emotional disorders. The primary therapeutic problem in children with cerebral palsy is learning to move in a lower position and learning to walk. The aim of this research is evaluation the action of the botulinum toxin on gait pattern of children with cerebral palsy. Application of a comprehensive BTS analysis of gait will get accurate, consistent EBM (Evidence Base Medicine) results. The children with pyramidal syndrome of juvenile cerebral palsy have been included in the examinations. The children have been divided into 2 random groups: group I--children treated with standard therapy a neurodevelopmental rehabilitation and classic kinesiotherapy, group II--hildren treated with standard therapy --eurodevelopmental rehabilitation, classic kinesiotherapy and a botulinum toxin. The children were examined three times: before the therapy, after 6 weeks of treatment and after 3 months of treatment. In the research BTS comprehensive motion analysis system have been used where influence of toxin botulin on walk stereotype of children was assessed. The treatment connected with standard rehabilitation and using botulinum toxin brings quicker walk improvement. Comparing the above treatment methods of influence on the walk stereotype of children with juvenile cerebral palsy, we can confirm, that standard treatment brings regular improvement, still, it requires longer period of time, often even 3 months. Using botulinum toxin brings quicker walk improvement

  16. Comprehensive eye evaluation algorithm

    Science.gov (United States)

    Agurto, C.; Nemeth, S.; Zamora, G.; Vahtel, M.; Soliz, P.; Barriga, S.

    2016-03-01

    In recent years, several research groups have developed automatic algorithms to detect diabetic retinopathy (DR) in individuals with diabetes (DM), using digital retinal images. Studies have indicated that diabetics have 1.5 times the annual risk of developing primary open angle glaucoma (POAG) as do people without DM. Moreover, DM patients have 1.8 times the risk for age-related macular degeneration (AMD). Although numerous investigators are developing automatic DR detection algorithms, there have been few successful efforts to create an automatic algorithm that can detect other ocular diseases, such as POAG and AMD. Consequently, our aim in the current study was to develop a comprehensive eye evaluation algorithm that not only detects DR in retinal images, but also automatically identifies glaucoma suspects and AMD by integrating other personal medical information with the retinal features. The proposed system is fully automatic and provides the likelihood of each of the three eye disease. The system was evaluated in two datasets of 104 and 88 diabetic cases. For each eye, we used two non-mydriatic digital color fundus photographs (macula and optic disc centered) and, when available, information about age, duration of diabetes, cataracts, hypertension, gender, and laboratory data. Our results show that the combination of multimodal features can increase the AUC by up to 5%, 7%, and 8% in the detection of AMD, DR, and glaucoma respectively. Marked improvement was achieved when laboratory results were combined with retinal image features.

  17. [Designing and Operating a Comprehensive Mental Health Management System to Support Faculty at a University That Contains a Medical School and University Hospital].

    Science.gov (United States)

    Kawanishi, Chiaki

    2016-01-01

    In Japan, healthcare professionals and healthcare workers typically practice a culture of self-assessment when it comes to managing their own health. Even where this background leads to instances of mental health disorders or other serious problems within a given organization, such cases are customarily addressed by the psychiatrists or psychiatric departments of the facilities affected. Organized occupational mental health initiatives for professionals and workers within the healthcare system are extremely rare across Japan, and there is little recognition of the need for such initiatives even among those most directly affected. The author has some experience designing and operating a comprehensive health management system to support students and faculty at a university in the Tokyo Metropolitan Area that contains a medical school and university hospital. At this university, various mental health-related problems were routinely being allowed to develop into serious cases, while the fundamental reforms required by the health management center and the mental health management scheme organized through the center had come to represent a challenge for the entire university. From this initial situation, we undertook several successive initiatives, including raising the number of staff in the health management center and its affiliated organizations, revising and drafting new health management rules and regulations, launching an employment support and management system, implementing screenings to identify people with mental ill-health, revamping and expanding a counselling response system, instituting regular collaboration meetings with academic affairs staff, and launching educational and awareness-raising activities. This resulted in the possibility of intervention in all cases of mental health crisis, such as suicidal ideation. We counted more than 2,400 consultations (cumulative total number; more than half of consultations was from the medical school, postgraduate

  18. Case in Language Comprehension

    NARCIS (Netherlands)

    Bader, Markus; Lamers, Monique

    2012-01-01

    Research on human language comprehension has been heavily influenced by properties of the English language. Since case plays only a minor role in English, its role for language comprehension has only recently become a topic for extensive research on psycholinguistics. In the psycholinguistic

  19. Spectrum of Physics Comprehension

    Science.gov (United States)

    Blasiak, W.; Godlewska, M.; Rosiek, R.; Wcislo, D.

    2012-01-01

    The paper presents the results of research on the relationship between self-assessed comprehension of physics lectures and final grades of junior high school students (aged 13-15), high school students (aged 16-18) and physics students at the Pedagogical University of Cracow, Poland (aged 21). Students' declared level of comprehension was measured…

  20. Comprehensive Comparisons of Satellite Data, Signals, and Measurements between the BeiDou Navigation Satellite System and the Global Positioning System

    Science.gov (United States)

    Jan, Shau-Shiun; Tao, An-Lin

    2016-01-01

    The Chinese BeiDou navigation satellite system (BDS) aims to provide global positioning service by 2020. The combined use of BDS and Global Positioning System (GPS) is proposed to provide navigation service with more stringent requirements. Actual satellite data, signals and measurements were collected for more than one month to analyze the positioning service qualities from both BDS and GPS. In addition to the conversions of coordinate and timing system, five data quality analysis (DQA) methods, three signal quality analysis (SQA) methods, and four measurement quality analysis (MQA) methods are proposed in this paper to improve the integrated positioning performance of BDS and GPS. As shown in the experiment results, issues related to BDS and GPS are resolved by the above proposed quality analysis methods. Thus, the anomalies in satellite data, signals and measurements can be detected by following the suggested resolutions to enhance the positioning performance of the combined use of BDS and GPS in the Asia Pacific region. PMID:27187403

  1. Financial planning on a comprehensive scale.

    Science.gov (United States)

    Mishra, Simita

    2013-04-01

    Hospitals and health systems that wish to explore the shift to comprehensive care management should: Assess the investments in infrastructure necessary to support comprehensive care management, Gauge the financial implications and set quality and financial goals, Monitor performance using metrics such as patient satisfaction, avoidable admissions, out-of-group referrals, and average length of stay.

  2. Motion control system of MAX IV Laboratory soft x-ray beamlines

    International Nuclear Information System (INIS)

    Sjöblom, Peter; Lindberg, Mirjam; Forsberg, Johan; Persson, Andreas G.; Urpelainen, Samuli; Såthe, Conny

    2016-01-01

    At the MAX IV Laboratory, five new soft x-ray beamlines are under development. The first is Species and it will be used to develop and set the standard of the control system, which will be common across the facility. All motion axes at MAX IV will be motorized using stepper motors steered by the IcePAP motion controller and a mixture of absolute and incremental encoders following a predefined coordinate system. The control system software is built in Tango and uses the Python-based Sardana framework. The user controls the entire beamline through a synoptic overview and Sardana is used to run the scans.

  3. Motion control system of MAX IV Laboratory soft x-ray beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Sjöblom, Peter, E-mail: peter.sjoblom@maxlab.lu.se; Lindberg, Mirjam, E-mail: mirjam.lindberg@maxlab.lu.se; Forsberg, Johan, E-mail: johan.forsberg@maxlab.lu.se; Persson, Andreas G., E-mail: andreas-g.persson@maxlab.lu.se; Urpelainen, Samuli, E-mail: samuli.urpelainen@maxlab.lu.se; Såthe, Conny, E-mail: conny.sathe@maxlab.lu.se [MAX IV Laboratory, Photongatan 2, 225 92 Lund (Sweden)

    2016-07-27

    At the MAX IV Laboratory, five new soft x-ray beamlines are under development. The first is Species and it will be used to develop and set the standard of the control system, which will be common across the facility. All motion axes at MAX IV will be motorized using stepper motors steered by the IcePAP motion controller and a mixture of absolute and incremental encoders following a predefined coordinate system. The control system software is built in Tango and uses the Python-based Sardana framework. The user controls the entire beamline through a synoptic overview and Sardana is used to run the scans.

  4. Quotient-Comprehension Chains

    Directory of Open Access Journals (Sweden)

    Kenta Cho

    2015-11-01

    Full Text Available Quotients and comprehension are fundamental mathematical constructions that can be described via adjunctions in categorical logic. This paper reveals that quotients and comprehension are related to measurement, not only in quantum logic, but also in probabilistic and classical logic. This relation is presented by a long series of examples, some of them easy, and some also highly non-trivial (esp. for von Neumann algebras. We have not yet identified a unifying theory. Nevertheless, the paper contributes towards such a theory by introducing the new quotient-and-comprehension perspective on measurement instruments, and by describing the examples on which such a theory should be built.

  5. Comprehensive cardiac rehabilitation

    DEFF Research Database (Denmark)

    Kruse, Marie; Hochstrasser, Stefan; Zwisler, Ann-Dorthe O

    2006-01-01

    OBJECTIVES: The costs of comprehensive cardiac rehabilitation are established and compared to the corresponding costs of usual care. The effect on health-related quality of life is analyzed. METHODS: An unprecedented and very detailed cost assessment was carried out, as no guidelines existed...... and may be as high as euro 1.877. CONCLUSIONS: Comprehensive cardiac rehabilitation is more costly than usual care, and the higher costs are not outweighed by a quality of life gain. Comprehensive cardiac rehabilitation is, therefore, not cost-effective....

  6. Emergency preparedness: a comprehensive plan

    International Nuclear Information System (INIS)

    Wilson, R.H.

    1975-01-01

    The Atlantic Richfield Hanford Company (ARHCO) has developed comprehensive plans for coping with emergencies ranging from criticality to civil disturbance. A unique notification system provides for immediate contact with key personnel by using a central communications center, crash alarm warning networks, and a continuing telephone cascade notification system. There is also the capability of immediately contacting other contractor key personnel. Certain jobs have been predetermined as necessary for coping with an emergency. An emergency staff consisting of responsible management, with alternates, has been preselected to automatically fill these jobs when notified. Control centers for headquarters and ''field'' are established with telephone and radio communication capabilities and are also supplied with some source materials to assist initiating plans for containing an emergency for recovery. A comprehensive emergency procedures manual has been developed, which contains information of company-wide application and procedures for specific facilities covering almost all accident situations

  7. Demands on project management of comprehensive modernization projects in the electrical systems area. Example of modernization of electrical systems of Kozloduy NPP Unit 5 and 6

    International Nuclear Information System (INIS)

    Stinshoff, Helmut; Weber, Patrick

    2006-01-01

    In nuclear power plants, station supply with electric energy must be guaranteed any time. This applies in particular also during the implementation of complex electrical systems modernization projects. Highest demands on the project management, extensive experience and system knowledge are required. In the frame of the Modernization Program for the nuclear power plant Kozloduy unit 5 and 6 in Bulgaria Framatome ANP has approved its ability to implement a large scope of modernization measures during the refueling outages of the years 2003 to 2005. The Contract of the Modernization Program for the European Consortium Kozloduy (Framatome ANP, Atomenergoexport) was signed in July 1999 and became effective in June 2001. The project will be finished by May 2006, with the approval of the Updated Final Safety Analysis Report. The scope of hardware work has been implemented within 6 plant outages during the years 2002 to 2005. The focus of the Modernization Program is mainly oriented to nuclear safety aspects, with the aim of upgrading of the Units to a high safety level in compliance with international practice. A further section of the project is dedicated to upgrading of operational equipment. Framatome ANP personnel have shown that besides the technical challenges which had to be faced, also the intercultural and language barriers were successfully overcome. The good teamwork between the partners of the Consortium ECK, its Bulgarian subcontractors and with Kozloduy plant personnel has been an important success factor. (authors)

  8. Alarm management a comprehensive guide

    CERN Document Server

    Hollifield, Bill R

    2011-01-01

    In this second edition, Alarm Management: A Comprehensive Guide, various problems of alarm systems are covered with precise guidance on how they come about and how to effectively correct them. It is written by individuals with vast experience in the different plants, processes, and environments requiring effective alarm management. The second edition is filled with good examples and explanations of procedures, with practical lists and tips on how one should proceed. It is based on hundreds of successful projects.

  9. PyParse: a semiautomated system for scoring spoken recall data.

    Science.gov (United States)

    Solway, Alec; Geller, Aaron S; Sederberg, Per B; Kahana, Michael J

    2010-02-01

    Studies of human memory often generate data on the sequence and timing of recalled items, but scoring such data using conventional methods is difficult or impossible. We describe a Python-based semiautomated system that greatly simplifies this task. This software, called PyParse, can easily be used in conjunction with many common experiment authoring systems. Scored data is output in a simple ASCII format and can be accessed with the programming language of choice, allowing for the identification of features such as correct responses, prior-list intrusions, extra-list intrusions, and repetitions.

  10. Comprehensive geriatric assessment

    African Journals Online (AJOL)

    2007-09-14

    Sep 14, 2007 ... i.e. difficulty performing simple physical and mental tasks necessary for daily life. ... Definition. Comprehensive geriatric assessment (CGA) is a multidimensional .... The formation of a programme of therapy is decided on.

  11. Enhancing Engineering Students’ Reading Comprehension of English for Science and Technology With the Support of an Online Cumulative Sentence Analysis System

    Directory of Open Access Journals (Sweden)

    Yea-Ru Tsai

    2014-09-01

    Full Text Available For engineering students, reading in English is the core competence to absorb professional knowledge in academic settings and their future career, because many authentic textbooks and information about advanced technology have been published in English. The present study sets out to improve English reading comprehension among tertiary-level engineering students. An online reading strategy instruction based on cumulative sentence analysis (CSA was constructed to enhance the students’ reading comprehension of English technology texts. The comparison between the pre-test and post-test showed that the participants achieved a higher level of reading comprehension performance following the instruction. The findings clearly demonstrated that online CSA strategy instruction is an efficient and feasible approach to helping engineering students cope with their problems of reading English texts. Pedagogical implications are briefly discussed based on the findings of this study.

  12. Readmission after treatment of Grade 3 and 4 renal injuries at a Level I trauma center: Statewide assessment using the Comprehensive Hospital Abstract Reporting System.

    Science.gov (United States)

    Winters, Brian; Wessells, Hunter; Voelzke, Bryan B

    2016-03-01

    One criticism of the existing renal trauma research is the limited outpatient follow-up after index hospitalization. We assessed readmission rates following treatment for American Association for the Surgery of Trauma (AAST) Grade 3 and 4 renal injury using the Comprehensive Hospital Abstract Reporting System (CHARS). We evaluated all patients with AAST Grade 3 and 4 renal injuries admitted to Harborview Medical Center (HMC) between 1998 and 2010, the only Level 1 trauma center in Washington state. Grade 4 renal injuries were stratified by collecting system laceration (CSL) or segmental vascular injury. Data were abstracted from the CHARS database for readmissions to any Washington state hospital within 6 months of renal injury. Clinical variables, diagnoses, and procedures were queried based on DRG International Classification of Diseases-9th Rev. codes. A total of 477 Grade 3 and 159 Grade 4 renal injuries were initially treated at HMC. On admission, 111 patients required intervention: 75 (16%) of 477 Grade 3 and 36 (23%) of 159 Grade 4 injuries. Within 6 months of index hospitalization, 86 (18%) of 477 Grade 3 and 38 (24%) of 159 Grade 4 patients were readmitted to any Washington state hospital. Eighty percent of Grade 3 injuries and 66% of Grade 4 injuries returned to HMC compared with secondary hospitals (p = 0.08). At readmission, 19 (22%) of 86 Grade 3 and 16 (42%) of 38 Grade 4 injuries had a urologic diagnosis. Subsequent procedural intervention was required on readmission in 6 (7%) of 86 Grade 3 and 5 (13%) of 38 Grade 4 renal injuries (all CSL injuries). A subset of patients treated for Grade 3 and 4 renal trauma will be readmitted for further management. While urologic diagnoses and additional procedures may be low overall, readmission to outside hospitals may preclude accurate determination of renal trauma outcomes. Based on these data, patients with Grade 4 CSL injuries seem to be at the highest risk for readmission and to require a subsequent

  13. A Study to Determine the Effects of a Comprehensive and Experiential System of Vocational Guidance and Career Development on Junior High School Pupils. Final Report.

    Science.gov (United States)

    Ehresman, Norman D.; Vincent, Roger D.

    Comprehensive work experience and vocational guidance activities were established at the middle school level and their effects on career maturity and attitudes toward school of ninth graders were tested. The project was conducted at the Bowling Green Junior High School (Kentucky) during the academic school year of 1975-76. (The school supports a…

  14. "Teaching Case": ComprehensiveCare and the Re-Adoption of an Electronic Health Records System: Preparing for a Successful Adoption after a Failed Attempt

    Science.gov (United States)

    Gomillion, David L.

    2017-01-01

    After a prior failed adoption, ComprehensiveCare plans for a second attempt in adopting Electronic Health Records. The owner-physicians on the board of directors have replaced the administrator due in part to the missteps of the prior adoption. William Shoemaker, the new administrator, must grapple with several important decisions to provide the…

  15. Report on comprehensive surveys of nationwide geothermal resources in fiscal 1979. Conceptual design of a database system; 1979 nendo zenkoku chinetsu shigen sogo chosa hokokusho. Database system gainen sekkei

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1980-03-31

    Conceptual design was made on a database system as part of the comprehensive surveys of nationwide geothermal resources. Underground hot water in depths of several kilometers close to the ground surface is a utilizable geothermal energy. Exploration using the ground surface survey is much less expensive than the test drilling survey, but has greater error in estimation because of being an indirect method. However, integrating data by freely using a number of exploration methods can improve the accuracy of estimation on the whole. In performing the conceptual design of a geothermal resource information system, the functions of this large scale database were used as the framework. Further data collection, distribution and interactive type man-machine communication, modeling, and environment surveillance functions were incorporated. Considerations were also given on further diversified utilization patterns and on support to users in remote areas and end users. What is important in designing the system is that constituting elements of hardware and software should function while being combined organically as one system, rather than the elements work independently. In addition, sufficient expandability and flexibility are indispensable. (NEDO)

  16. Hybrid palliation for critical systemic outflow obstruction: neither rapid stage 1 Norwood nor comprehensive stage 2 mitigate consequences of early risk factors.

    Science.gov (United States)

    Davies, Ryan R; Radtke, Wolfgang; Bhat, Majeed A; Baffa, Jeanne M; Woodford, Edward; Pizarro, Christian

    2015-01-01

    Hybrid palliation with branch pulmonary artery banding (bPAB) has become increasingly common in the early management of patients with critical left ventricular outflow obstruction. Optimal subsequent surgical palliation remains undefined. We retrospectively reviewed patients undergoing initial bPAB for single ventricle physiology with systemic outflow obstruction (2001-2013, n = 37). Patients were stratified by subsequent surgical palliation: stage 1 Norwood (St1N, n = 14), comprehensive stage 2 (CompSt2, n = 11), and none (n = 12). bPAB was performed at a median of 4 days and 2.7-kg, post-bPAB mortality was increased in patients with aortic atresia (odds ratio [OR] = 3.8, 95% confidence interval [CI] = 0.9-15.8) or birth weight <2 kg (OR = 13.8, 95% CI = 1.4-136.4). Palliation strategy did not affect transplant-free survival through second-stage palliation (St1N: 71.4%, CompSt2: 72.7%, P = .9). Among CompSt2 patients, there was a trend toward poorer survival with aortic atresia (0% vs 80%, P = .09); birth weight <2.5 kg was associated with decreased survival (0% vs 89.0%, P = .01). A trend toward lower survival with low birth weight was evident among St1N patients (<2 kg, OR = 0.1, 95% CI = 0.01-1.9, P = .09). CompSt2 mortality occurred on postoperative days 0 and 1. Mortality following St1N occurred at a median of 38.5 days (range = 23.5-104.5). Among survivors of stage 2 palliation, Fontan completion was performed in the same number of patients in each group (St1N: 6/8, 75%, CompSt2: 6/8, 75%). Both St1N and CompSt2 are viable options for subsequent palliation following initial hybrid procedure. Transplant-free survival and eventual Fontan candidacy are similar between groups. Delaying surgical palliation with the CompSt2 did not mitigate the impact of early risk factors such as low birth weight and aortic atresia. Copyright © 2015 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

  17. DESIGN OF A VIBRATION AND STRESS MEASUREMENT SYSTEM FOR AN ADVANCED POWER REACTOR 1400 REACTOR VESSEL INTERNALS COMPREHENSIVE VIBRATION ASSESSMENT PROGRAM

    OpenAIRE

    KO, DO-YOUNG; KIM, KYU-HYUNG

    2013-01-01

    In accordance with the US Nuclear Regulatory Commission (US NRC), Regulatory Guide 1.20, the reactor vessel internals comprehensive vibration assessment program (RVI CVAP) has been developed for an Advanced Power Reactor 1400 (APR1400). The purpose of the RVI CVAP is to verify the structural integrity of the reactor internals to flow-induced loads prior to commercial operation. The APR1400 RVI CVAP consists of four programs (analysis, measurement, inspection, and assessment). Thoughtful prepa...

  18. THE NATURE OF COMPREHENSION.

    Science.gov (United States)

    CLELAND, DONALD L.

    THE NATURE OF COMPREHENSION IS DEFINED AND CLARIFIED. THE LITERATURE IS SURVEYED TO SHOW THAT THE DEVELOPMENT OF CONCEPTS IS IMPORTANT IN INTELLECTUAL ACTIVITIES. IT IS POINTED OUT THAT CONCEPTS ARE BUILT FROM PERCEPTS, IMAGES, SENSATION, AND MEMORIES, AND THAT THE STEPS WHICH ARE EMPLOYED AS CONCEPTS ARE BUILT AND REFINED AND INCLUDE PERCEIVING,…

  19. Comprehension Strategy Gloves.

    Science.gov (United States)

    Newman, Gayle

    2002-01-01

    Describes the idea of creating a glove for each of the comprehension strategies for use with different text structures. Notes that the gloves serve as a multisensory approach by providing visual clues through icons on each finger and the palm. Discusses three different gloves: the prereading glove, the narrative text structure glove, and the…

  20. Painless reading comprehension

    CERN Document Server

    Jones, EdD, Darolyn "Lyn"

    2016-01-01

    Reading comprehension gets easier as students learn what kind of reader they are, discover how to keep facts in their head, and much more. Bonus Online Component: includes additional games, including Beat the Clock, a line match game, and a word scramble.

  1. Comprehensive Environmental Management Process

    International Nuclear Information System (INIS)

    Hjeresen, D.L.; Roybal, S.L.

    1994-01-01

    This report contains information about Los Alamos National Laboratory's Comprehensive Environmental Management Plan. The topics covered include: waste minimization, waste generation, environmental concerns, public relations of the laboratory, and how this plan will help to answer to the demands of the laboratory as their mission changes

  2. A comprehensive psychiatric service

    DEFF Research Database (Denmark)

    Wang, A G

    1984-01-01

    A comprehensive psychiatric service was established in 1969 in the Faroe Islands. This service was created as a department of a general hospital. The spheres covered by this department, operating in the midst of the community were: acute and chronic patients, a liaison-psychiatric service...

  3. The safety culture according to a comprehensive approach. A contribution to risk governance within complex systems. Doctoral thesis prepared at SCK-CEN and defended in 2004

    International Nuclear Information System (INIS)

    Fucks, I.

    2005-01-01

    The article refers to an abstract of a doctoral thesis. This PhD is based on two evolutions within the society concerning the way to manage modern risks. It is more and more acknowledged that, firstly, rational scientific models are no longer capable to explain and manage the complexity and the diversity of risks. Secondly the supporters of a democratic conception of the risk governance claim that the risk management can benefit from the participation of the lay people to the debate. Within this framework, the study of safety culture, according to a bottom-up and comprehensive approach, in the field of the social sciences, represents an opportunity to make concrete the risk governance principle within complex system (such as a nuclear power plant and a nuclear research centre). The objectives of this PhD are the following: to appreciate the participation of the workers to the debate of the risk management within organisations; to present the lessons which can be drawn from this exercise and finally to investigate the safety culture of different groups of workers adopting an alternative view as compared to the vision as formulated in the present texts of the IAEA.The methodology was based on two techniques: observation and Focus Group. The observations were planed to feed further the Focus Group discussions with concrete examples of situations at work. We organized different Focus Group discussions with different kinds of workers (workers, managers, safety officers) in order to collect the social representation relating to the safety, the organization, the technology, the socio-economical environment and the work of each of these groups, both in the Belgian Nuclear Research Centre and in the Nuclear Power Plant of Tricastin in France. The results confirm firstly the relevance of developing a multidisciplinary theoretical framework of safety culture drawing its inspiration from sociology, social psychology, anthropology, etc. This multidisciplinary approach allows

  4. Cognitive Correlates of Listening Comprehension

    Science.gov (United States)

    Kim, Young-Suk; Phillips, Beth

    2014-01-01

    In an effort to understand cognitive foundations of oral language comprehension (i.e., listening comprehension), we examined how inhibitory control, theory of mind, and comprehension monitoring are uniquely related to listening comprehension over and above vocabulary and age. A total of 156 children in kindergarten and first grade from…

  5. Comprehensive hard materials

    CERN Document Server

    2014-01-01

    Comprehensive Hard Materials deals with the production, uses and properties of the carbides, nitrides and borides of these metals and those of titanium, as well as tools of ceramics, the superhard boron nitrides and diamond and related compounds. Articles include the technologies of powder production (including their precursor materials), milling, granulation, cold and hot compaction, sintering, hot isostatic pressing, hot-pressing, injection moulding, as well as on the coating technologies for refractory metals, hard metals and hard materials. The characterization, testing, quality assurance and applications are also covered. Comprehensive Hard Materials provides meaningful insights on materials at the leading edge of technology. It aids continued research and development of these materials and as such it is a critical information resource to academics and industry professionals facing the technological challenges of the future. Hard materials operate at the leading edge of technology, and continued res...

  6. 501 reading comprehension questions

    CERN Document Server

    2014-01-01

    This updated edition offers the most extensive and varied practice for all types of questions students might face on standardized and in-class tests. With this guide, students will learn to develop expert reading strategies, understand how to read faster and with greater comprehension, overcome reading anxiety, and increase appreciation of reading for pleasure. This book's step-by-step approach provides graduated coverage that moves from the basics to more advanced reading.

  7. SITE COMPREHENSIVE LISTING (CERCLIS) - Contaminants at CERCLIS (Superfund) Sites

    Data.gov (United States)

    U.S. Environmental Protection Agency — Contaminants at Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) (Superfund) Sites - The CERCLIS Public Access Database...

  8. SITE COMPREHENSIVE LISTING (CERCLIS) (Superfund) - Responsible Parties at CERCLIS Sites

    Data.gov (United States)

    U.S. Environmental Protection Agency — Responsible Parties at CERCLIS Sites - The Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) (Superfund) Public Access...

  9. SITE COMPREHENSIVE LISTING (CERCLIS) (Superfund) - Non-NPL Sites

    Data.gov (United States)

    U.S. Environmental Protection Agency — Non-NPL Sites - The Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) (Superfund) Public Access Database contains a...

  10. A comprehensive French grammar

    CERN Document Server

    Price, Glanville

    2013-01-01

    Characterized by clear and accessible explanations, numerous examples and sample sentences, a new section on register and tone, and useful appendices covering topics including age and time, A Comprehensive French Grammar, Sixth Edition is an indispensable tool for advanced students of French language and literature.A revised edition of this established, bestselling French grammarIncludes a new section on register and medium and offers expanded treatment of French punctuationFeatures numerous examples and sample sentences, and useful appendices covering topics including age, time, and dimension

  11. Comprehensive multiplatform collaboration

    Science.gov (United States)

    Singh, Kundan; Wu, Xiaotao; Lennox, Jonathan; Schulzrinne, Henning G.

    2003-12-01

    We describe the architecture and implementation of our comprehensive multi-platform collaboration framework known as Columbia InterNet Extensible Multimedia Architecture (CINEMA). It provides a distributed architecture for collaboration using synchronous communications like multimedia conferencing, instant messaging, shared web-browsing, and asynchronous communications like discussion forums, shared files, voice and video mails. It allows seamless integration with various communication means like telephones, IP phones, web and electronic mail. In addition, it provides value-added services such as call handling based on location information and presence status. The paper discusses the media services needed for collaborative environment, the components provided by CINEMA and the interaction among those components.

  12. Fundamental Reform of Payment for Adult Primary Care: Comprehensive Payment for Comprehensive Care

    Science.gov (United States)

    Berenson, Robert A.; Schoenbaum, Stephen C.; Gardner, Laurence B.

    2007-01-01

    Primary care is essential to the effective and efficient functioning of health care delivery systems, yet there is an impending crisis in the field due in part to a dysfunctional payment system. We present a fundamentally new model of payment for primary care, replacing encounter-based imbursement with comprehensive payment for comprehensive care. Unlike former iterations of primary care capitation (which simply bundled inadequate fee-for-service payments), our comprehensive payment model represents new investment in adult primary care, with substantial increases in payment over current levels. The comprehensive payment is directed to practices to include support for the modern systems and teams essential to the delivery of comprehensive, coordinated care. Income to primary physicians is increased commensurate with the high level of responsibility expected. To ensure optimal allocation of resources and the rewarding of desired outcomes, the comprehensive payment is needs/risk-adjusted and performance-based. Our model establishes a new social contract with the primary care community, substantially increasing payment in return for achieving important societal health system goals, including improved accessibility, quality, safety, and efficiency. Attainment of these goals should help offset and justify the costs of the investment. Field tests of this and other new models of payment for primary care are urgently needed. PMID:17356977

  13. The mechanism of enhanced wastewater nitrogen removal by photo-sequencing batch reactors based on comprehensive analysis of system dynamics within a cycle.

    Science.gov (United States)

    Ye, Jianfeng; Liang, Junyu; Wang, Liang; Markou, Giorgos

    2018-07-01

    To understand the mechanism of enhanced nitrogen removal by photo-sequencing batch reactors (photo-SBRs), which incorporated microalgal photosynthetic oxygenation into the aerobic phases of a conventional cycle, this study performed comprehensive analysis of one-cycle dynamics. Under a low aeration intensity (about 0.02 vvm), a photo-SBR, illuminated with light at 92.27 μ·mol·m -2 ·s -1 , could remove 99.45% COD, 99.93% NH 4 + -N, 90.39% TN, and 95.17% TP, while the control SBR could only remove 98.36% COD, 83.51% NH 4 + -N, 78.96% TN, and 97.75% TP, for a synthetic domestic sewage. The specific oxygen production rate (SOPR) of microalgae in the photo-SBR could reach 6.63 fmol O 2 ·cell -1 ·h -1 . One-cycle dynamics shows that the enhanced nitrogen removal by photo-SBRs is related to photosynthetic oxygenation, resulting in strengthened nitrification, instead of direct nutrient uptake by microalgae. A too high light or aeration intensity could deteriorate anoxic conditions and thus adversely affect the removal of TN and TP in photo-SBRs. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. How reading comprehension is embodied and why that matters

    Directory of Open Access Journals (Sweden)

    Arthur M. GLENBERG

    2011-11-01

    Full Text Available Reading comprehension, much like comprehension of situations and comprehension of oral language, is embodied. In all cases, comprehension is the ability to take effective action on the basis ofaffordances related to the body, the physical world, and personal goals and cultural norms. In language contexts, action-based comprehension arises from simulating the linguistic content usingneural and bodily systems of perception, action, and emotion. Within this framework, a new approach to teaching reading comprehension is described: Teach children how to simulate while reading. TheMoved by Reading intervention teaches simulation in two stages. In the first stage, physical manipulation, children manipulate toys to simulate the content of what they are reading. After success in physically manipulating the toys, the children are taught to manipulate the toys in imagination. Research demonstrates that both physical and imagined manipulation leads to large gains in memory and comprehension.

  15. How reading comprehension is embodied and why that matters

    Directory of Open Access Journals (Sweden)

    Arthur M. Glenberg

    2011-10-01

    Full Text Available Reading comprehension, much like comprehension of situations and comprehension of oral language, is embodied. In all cases, comprehension is the ability to take effective action on the basis of affordances related to the body, the physical world, and personal goals and cultural norms. In language contexts, action-based comprehension arises from simulating the linguistic content using neural and bodily systems of perception, action, and emotion. Within this framework, a new approach to teaching reading comprehension is described: Teach children how to simulate while reading. The Moved by Reading intervention teaches simulation in two stages. In the first stage, physical manipulation, children manipulate toys to simulate the content of what they are reading. After success in physically manipulating the toys, the children are taught to manipulate the toys in imagination. Research demonstrates that both physical and imagined manipulation leads to large gains in memory and comprehension.

  16. Check and evaluation system on heat metering and energy efficiency retrofit of existing residential buildings in northern heating areas of china based on multi-index comprehensive evaluation method

    International Nuclear Information System (INIS)

    Zhao Jing; Wu Yong; Zhu Neng

    2009-01-01

    Heat metering and energy efficiency retrofit of existing residential buildings in northern heating areas of China is organized and implemented in a large scale by local government in 15 provinces of North China with the unified guidance and control of central government. Firstly, this paper introduced the target of energy-saving reformation of existing residential buildings in North China and the importance of check and evaluation on this target, then pointed out the necessity of building up an evaluation system for energy-saving retrofit. According to the analytical hierarchy process (AHP), three-grade evaluation system was built up for heat metering and energy efficiency retrofit of existing residential buildings in northern heating areas of China. Also, based on multi-index comprehensive evaluation method combined with life cycle assessment (LCA) theory, post-evaluation thought and successful degree evaluation method, a mathematical model was established. Finally, a set of scientific method for evaluating heat metering and energy efficiency retrofit of existing residential buildings in northern heating areas of China systematically, scientifically, comprehensively and objectively was created.

  17. Psychodermatology: A comprehensive review

    Directory of Open Access Journals (Sweden)

    Savita Yadav

    2013-01-01

    Full Text Available Psychodermatology is an interesting domain of dermatology that overlaps with psychiatry. This arena in dermatology has received limited diligence, partly due to lack of training in this realm. We present here a comprehensive review of salient features and treatment updates in primary psychiatric dermatoses and have also discussed the role of psyche in psychophysiological cutaneous disorders. Secondary psychiatric morbidity is relatively common among patients visiting the dermatologists but often overlooked and uncared for. Dermatologist should be able to initiate basic pharmacotherapy, should be knowledgeable about various non-pharmacological treatments and know the right time to refer the patient to the psychiatrist. Awareness and pertinent treatment of psychodermatological disorders among dermatologists will lead to a more holistic treatment approach and better prognosis in this unique group of patients.

  18. Comprehensive Environmental Management Plan

    International Nuclear Information System (INIS)

    Hjeresen, D.L.

    1994-01-01

    The Environmental Management Program at Los Alamos National Laboratory is in the process of initiating and then implementing a Comprehensive Environmental Management Plan (CEMP). There are several environmental impact and compliance drivers for this initiative. The Los Alamos CEMP is intended to be a flexible, long-range process that predicts, minimizes, treats, and disposes of any waste generated in execution of the Los Alamos mission - even if that mission changes. The CEMP is also intended to improve stakeholder and private sector involvement and access to environmental information. The total quality environmental management (TQEM) process will benchmark Los Alamos to private sector and DOE operations, identify opportunities for improvement, prioritize among opportunities, implement projects, measure progress, and spur continuous improvement in Environmental Management operations

  19. Comprehensive nuclear materials

    CERN Document Server

    Allen, Todd; Stoller, Roger; Yamanaka, Shinsuke

    2012-01-01

    Comprehensive Nuclear Materials encapsulates a panorama of fundamental information on the vast variety of materials employed in the broad field of nuclear technology. The work addresses, in five volumes, 3,400 pages and over 120 chapter-length articles, the full panorama of historical and contemporary international research in nuclear materials, from Actinides to Zirconium alloys, from the worlds' leading scientists and engineers. It synthesizes the most pertinent research to support the selection, assessment, validation and engineering of materials in extreme nuclear environments. The work discusses the major classes of materials suitable for usage in nuclear fission, fusion reactors and high power accelerators, and for diverse functions in fuels, cladding, moderator and control materials, structural, functional, and waste materials.

  20. Lower Education Level Is a Risk Factor for Peritonitis and Technique Failure but Not a Risk for Overall Mortality in Peritoneal Dialysis under Comprehensive Training System.

    Science.gov (United States)

    Kim, Hyo Jin; Lee, Joongyub; Park, Miseon; Kim, Yuri; Lee, Hajeong; Kim, Dong Ki; Joo, Kwon Wook; Kim, Yon Su; Cho, Eun Jin; Ahn, Curie; Oh, Kook-Hwan

    2017-01-01

    Lower education level could be a risk factor for higher peritoneal dialysis (PD)-associated peritonitis, potentially resulting in technique failure. This study evaluated the influence of lower education level on the development of peritonitis, technique failure, and overall mortality. Patients over 18 years of age who started PD at Seoul National University Hospital between 2000 and 2012 with information on the academic background were enrolled. Patients were divided into three groups: middle school or lower (academic year≤9, n = 102), high school (912, n = 324). Outcomes were analyzed using Cox proportional hazards models and competing risk regression. A total of 655 incident PD patients (60.9% male, age 48.4±14.1 years) were analyzed. During follow-up for 41 (interquartile range, 20-65) months, 255 patients (38.9%) experienced more than one episode of peritonitis, 138 patients (21.1%) underwent technique failure, and 78 patients (11.9%) died. After adjustment, middle school or lower education group was an independent risk factor for peritonitis (adjusted hazard ratio [HR], 1.61; 95% confidence interval [CI], 1.10-2.36; P = 0.015) and technique failure (adjusted HR, 1.87; 95% CI, 1.10-3.18; P = 0.038), compared with higher than high school education group. However, lower education was not associated with increased mortality either by as-treated (adjusted HR, 1.11; 95% CI, 0.53-2.33; P = 0.788) or intent-to-treat analysis (P = 0.726). Although lower education was a significant risk factor for peritonitis and technique failure, it was not associated with increased mortality in PD patients. Comprehensive training and multidisciplinary education may overcome the lower education level in PD.

  1. A Comprehensive Analysis of Chromoplast Differentiation Reveals Complex Protein Changes Associated with Plastoglobule Biogenesis and Remodeling of Protein Systems in Sweet Orange Flesh1[OPEN

    Science.gov (United States)

    Wang, Lun; Deng, Xiuxin

    2015-01-01

    Globular and crystalloid chromoplasts were observed to be region specifically formed in sweet orange (Citrus sinensis) flesh and converted from amyloplasts during fruit maturation, which was associated with the composition of specific carotenoids and the expression of carotenogenic genes. Subsequent isobaric tag for relative and absolute quantitation (iTRAQ)-based quantitative proteomic analyses of purified plastids from the flesh during chromoplast differentiation and senescence identified 1,386 putative plastid-localized proteins, 1,016 of which were quantified by spectral counting. The iTRAQ values reflecting the expression abundance of three identified proteins were validated by immunoblotting. Based on iTRAQ data, chromoplastogenesis appeared to be associated with three major protein expression patterns: (1) marked decrease in abundance of the proteins participating in the translation machinery through ribosome assembly; (2) increase in abundance of the proteins involved in terpenoid biosynthesis (including carotenoids), stress responses (redox, ascorbate, and glutathione), and development; and (3) maintenance of the proteins for signaling and DNA and RNA. Interestingly, a strong increase in abundance of several plastoglobule-localized proteins coincided with the formation of plastoglobules in the chromoplast. The proteomic data also showed that stable functioning of protein import, suppression of ribosome assembly, and accumulation of chromoplast proteases are correlated with the amyloplast-to-chromoplast transition; thus, these processes may play a collective role in chromoplast biogenesis and differentiation. By contrast, the chromoplast senescence process was inferred to be associated with significant increases in stress response and energy supply. In conclusion, this comprehensive proteomic study identified many potentially new plastid-localized proteins and provides insights into the potential developmental and molecular mechanisms underlying chromoplast

  2. Justice foundations for the Comprehensive Law Movement.

    Science.gov (United States)

    Dewhurst, Dale

    2010-01-01

    Authors examining the developing dispute resolution alternatives to the adversarial system have identified nine converging "vectors" or alternatives in what has been termed the Comprehensive Law Movement. These authors have sought to understand how the developing vectors can remain separate and vibrant movements while sharing common ground. Some analyze these developments as being within law and legal practice, others see them as alternative approaches to law, and still others take a combined approach. It will be impossible to understand how these vectors have meaningful differences from law and legal practice if the search is limited to looking within law and legal practice. It will be impossible to understand how these vectors have meaningful commonalities with law and legal practice if the search is limited to looking external to law and legal practice. Instead of comparing the vectors with the adversarial system, higher order criteria are required. What is needed is a comprehensive and internally consistent super-system of norms; one that can be used to evaluate the adversarial system and the evolving vectors on an equal footing. An Aristotelian natural law virtue theory of justice can: (a) provide a functional guiding definition of justice; (b) serve as a comprehensive and internally consistent super-system of norms; and (c) provide the theoretical and evaluative foundation required to clarify the relationships among the adversarial system and the developing vectors. Finally, it will become clear why the Comprehensive Law Movement might be more appropriately conceptualized as the Comprehensive Justice Movement. Copyright © 2010 Elsevier Ltd. All rights reserved.

  3. A Comprehensive Mapping of Urinary Schistosomiasis Using ...

    African Journals Online (AJOL)

    A Comprehensive Mapping of Urinary Schistosomiasis Using Geographic Information Systems (GIS) in Kano State, Nigeria. ... The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more information about ...

  4. Comprehensive review of the maritime safety regimes.

    NARCIS (Netherlands)

    S. Knapp (Sabine); Ph.H.B.F. Franses (Philip Hans)

    2007-01-01

    textabstractThis report presents a comprehensive review of the maritime safety regimes and provides recommendations on how to improve the system. The results show a complex legal framework which generates a high amount of inspections and overlapping of inspection areas where no cross-recognition is

  5. Modeling human-water-systems: towards a comprehensive and spatially distributed assessment of co-evolutions for river basins in Central Europe

    OpenAIRE

    P. Krahe; E. Nilson; M. Knoche; A.-D. Ebner von Eschenbach

    2016-01-01

    In the context of river basin and flood risk management there is a growing need to improve the understanding of and the feedbacks between the driving forces “climate and socio-economy” and water systems. We make use of a variety of data resources to illustrate interrelationships between different constituents of the human-water-systems. Taking water storage for energy production as an example we present a first analysis on the co-evolution of socio-economic and hydrological ...

  6. Grid-Connected Semitransparent Building-Integrated Photovoltaic System: The Comprehensive Case Study of the 120 kWp Plant in Kunming, China

    Directory of Open Access Journals (Sweden)

    Yunfeng Wang

    2018-01-01

    Full Text Available A 120 kWp building-integrated photovoltaic (BIPV system was installed on the south facade of the Solar Energy Research Institute building in Yunnan Normal University. The area of the curtain wall was 1560 m2 (26 m × 60 m, which consisted of 720 semitransparent monocrystalline silicon double-glazing PV panels. This paper studied the yearly and monthly variations of power generation in terms of solar data and meteorological parameters. The total amount of power generation of the BIPV system measured from October 2014 to September 2015 was 64.607 MWh, and the simulation results with TRNSYS (Transient Systems Simulation Program provided the 75.515 MWh predicted value of annual electricity production with the meteorological database of Meteonorm, while, based on the average value of the performance ratio (PR of 60% and the life cycle assessment (LCA of the system, the energy payback time (EPBT of 9.38 years and the potential for pollutant emission reductions have been evaluated and the environmental cost is RMB ¥0.01053 per kWh. Finally, an economic analysis was carried out; the net present value (NPV and the economic payback time of the BIPV system were estimated to be RMB ¥359,347 and 15 years, respectively.

  7. The 2001 Comprehensive Review

    CERN Multimedia

    Åkesson, T

    A new approach for CERN to monitor the LHC-experiments' technical and scientific progress was introduced last year: The Comprehensive Reviews. A significant fraction of the full LHCC committee is mobilized during two days to review the complete project status. This event took place for ATLAS during 2-3 of July this year. With a rather exhaustive program we presented our status in 39 talks. It was a demanding and close to impossible task for the referees to comprehend the ATLAS status by listening to this massive amount of information, but from the ATLAS point-of-view we judged it important that the referees were exposed to both the progress and the remaining problem areas. The referees were satisfied with our status; probably more so this year than last year. They judged the main critical issues to be: The schedules of the barrel toroid, the end-cap TRT, the LAr barrel and end-cap A, and the MDTs. The procurement of radiation hard electronics was also thought to be a critical issue. They were informed of ...

  8. Comprehensive facilities plan

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    The Ernest Orlando Lawrence Berkeley National Laboratory`s Comprehensive Facilities Plan (CFP) document provides analysis and policy guidance for the effective use and orderly future development of land and capital assets at the Berkeley Lab site. The CFP directly supports Berkeley Lab`s role as a multiprogram national laboratory operated by the University of California (UC) for the Department of Energy (DOE). The CFP is revised annually on Berkeley Lab`s Facilities Planning Website. Major revisions are consistent with DOE policy and review guidance. Facilities planing is motivated by the need to develop facilities for DOE programmatic needs; to maintain, replace and rehabilitate existing obsolete facilities; to identify sites for anticipated programmatic growth; and to establish a planning framework in recognition of site amenities and the surrounding community. The CFP presents a concise expression of the policy for the future physical development of the Laboratory, based upon anticipated operational needs of research programs and the environmental setting. It is a product of the ongoing planning processes and is a dynamic information source.

  9. Comprehensive Psychopathological Assessment Based on the Association for Methodology and Documentation in Psychiatry (AMDP) System: Development, Methodological Foundation, Application in Clinical Routine, and Research

    Science.gov (United States)

    Stieglitz, Rolf-Dieter; Haug, Achim; Fähndrich, Erdmann; Rösler, Michael; Trabert, Wolfgang

    2017-01-01

    The documentation of psychopathology is core to the clinical practice of the psychiatrist and clinical psychologist. However, both in initial as well as further training and specialization in their fields, this particular aspect of their work receives scanty attention only. Yet, for the past 50 years, the Association for Methodology and Documentation in Psychiatry (AMDP) System has been in existence and available as a tool to serve precisely the purpose of offering a systematic introduction to the terminology and documentation of psychopathology. The motivation for its development was based on the need for an assessment procedure for the reliable documentation of the effectiveness of newly developed psychopharmacological substances. Subsequently, the AMDP-System began to be applied in the context of investigations into a number of methodological issues in psychiatry (e.g., the frequency and specificity of particular symptoms, the comparison of rating scales). The System then became increasingly important also in clinical practice and, today, represents the most used instrument for the documentation of psychopathology in the German-speaking countries of Europe. This paper intends to offer an overview of the AMDP-System, its origins, design, and functionality. After an initial account of the history and development of the AMDP-System, the discussion will in turn focus on the System’s underlying methodological principles, the transfer of clinical skills and competencies in its practical application, and its use in research and clinical practice. Finally, potential future areas of development in relation to the AMDP-System are explored. PMID:28439242

  10. Establishing Comprehensive Experiment System of Microbiological Technologies and Cultivating Undergraduate' s Professional Scientific Literacy%构建微生物学技术综合实验体系 培养大学生科研素养

    Institute of Scientific and Technical Information of China (English)

    韩国民; 沈玲; 张明; 徐世红(编、校)

    2012-01-01

    为了培养学生实验设计能力,提高学生的实验基本功,以学生感兴趣的酒精制作工艺的各个环节为实验内容,构建了微生物学技术综合实验体系。在项目实施过程中将酒精制作工艺分解成酵母菌筛选、菌种鉴定、细胞固定化及酒精发酵等4个模块,在各个模块中融入多种基本实验技术,形成一个系统的综合性实验项目。本项目的实施有利于培养学生实验设计能力、数据分析能力和论文写作能力,以提高学生的科研素养。%In order to cultivate student' s ability of design experiment and enhance their techniques, we selected the manufacture craft of alcohol which was favored by students as the contents of experiment to establish comprehensive experiment system of microbiological technology. The manufacture craft was divided into four parts, i.e. selection of yeasts, identification, immobilization of cells and alcoholic fermentation. A large number of basic techniques were integrated into the four parts and formed a comprehensive experiment system. The experiment system is beneficial to cultivate student' s ability of design experiment, data analytical ability and academic writing capacity for cuhivating and enhancing students' professional scientific literacy.

  11. Cultural Knowledge in News Comprehension

    DEFF Research Database (Denmark)

    Mathieu, David

    2009-01-01

    This paper presents the main lines of the design and the findings of a reception study on news comprehension. This empirical study is a comparison of the comprehension processes of Danes and French Canadians over a set of news texts from both countries. Comprehension is explored from a cultural...... perspective, through the lens of cognition and pragmatics, revealing the role played by cultural knowledge in comprehension and the underlying relationship between a text and its intended audience. It is argued that recipients ‘problematise’ the news texts, a process by which the texts answer questions...

  12. Model aerodynamic test results for two variable cycle engine coannular exhaust systems at simulated takeoff and cruise conditions. Comprehensive data report. Volume 1: Design layouts

    Science.gov (United States)

    Nelson, D. P.

    1981-01-01

    The design layouts and detailed design drawings of coannular exhaust nozzle models for a supersonic propulsion system are presented. The layout drawings show the assembly of the component parts for each configuration. A listing of the component parts is also given.

  13. Effect of Computer Animation Technique on Students' Comprehension of the "Solar System and Beyond" Unit in the Science and Technology Course

    Science.gov (United States)

    Aksoy, Gokhan

    2013-01-01

    The purpose of this study is to determine the effect of computer animation technique on academic achievement of students in the "Solar System and Beyond" unit lecture as part of the Science and Technology course of the seventh grade in primary education. The sample of the study consists of 60 students attending to the 7th grade of primary school…

  14. Immersive Technology for Human-Centric Cyberphysical Systems in Complex Manufacturing Processes: A Comprehensive Overview of the Global Patent Profile Using Collective Intelligence

    Directory of Open Access Journals (Sweden)

    Usharani Hareesh Govindarajan

    2018-01-01

    Full Text Available Immersive technology for human-centric cyberphysical systems includes broad concepts that enable users in the physical world to connect with the cyberworld with a sense of immersion. Complex systems such as virtual reality, augmented reality, brain-computer interfaces, and brain-machine interfaces are emerging as immersive technologies that have the potential for improving manufacturing systems. Industry 4.0 includes all technologies, standards, and frameworks for the fourth industrial revolution to facilitate intelligent manufacturing. Industrial immersive technologies will be used for smart manufacturing innovation in the context of Industry 4.0’s human machine interfaces. This research provides a thorough review of the literature, construction of a domain ontology, presentation of patent metatrend statistical analysis, and data mining analysis using a technology function matrix and highlights technical and functional development trends using latent Dirichlet allocation (LDA models. A total of 179 references from the IEEE and IET databases and 2,672 patents are systematically analyzed to identify current trends. The paper establishes an essential foundation for the development of advanced human-centric cyberphysical systems in complex manufacturing processes.

  15. Do comprehensive schools reduce social mobility?

    Science.gov (United States)

    Boliver, Vikki; Swift, Adam

    2011-03-01

    This paper investigates the claim that the shift from a selective to a comprehensive school system had a deleterious effect on social mobility in Great Britain. Using data from the National Child Development Study, we compare the chances, for both class and income mobility, of those who attended different kinds of school. Where media attention focuses exclusively on the chances for upward mobility of those children from lowly origins who were (or would have been) judged worthy of selection into a grammar school, we offer more rounded analyses. We match respondents in a way that helps us to distinguish those inequalities in mobility chances that are due to differences between children from those due to differences between the schools they attended; we look at the effects of the school system on the mobility chances of all children, not merely those from less advantaged origins; and we compare comprehensive- and selective-system schools, not merely comprehensive and grammar schools. After matching, we find, first, that going to a grammar school rather than a comprehensive does not make low-origin children more likely to be upwardly mobile but it helps them move further if they are; second, that grammar schools do not benefit working-class children, in terms of class mobility, more than they benefit service-class children, but, in terms of income mobility, such schools benefit low-income children somewhat more than they benefit higher-income children - that benefit relating only to rather modest and limited movements within the income distribution. Finally, however, the selective system as a whole yields no mobility advantage of any kind to children from any particular origins: any assistance to low-origin children provided by grammar schools is cancelled out by the hindrance suffered by those who attended secondary moderns. Overall, our findings suggest that comprehensive schools were as good for mobility as the selective schools they replaced. © London School of

  16. Modeling human-water-systems: towards a comprehensive and spatially distributed assessment of co-evolutions for river basins in Central Europe

    Directory of Open Access Journals (Sweden)

    P. Krahe

    2016-05-01

    Full Text Available In the context of river basin and flood risk management there is a growing need to improve the understanding of and the feedbacks between the driving forces “climate and socio-economy” and water systems. We make use of a variety of data resources to illustrate interrelationships between different constituents of the human-water-systems. Taking water storage for energy production as an example we present a first analysis on the co-evolution of socio-economic and hydrological indicators. The findings will serve as for the development of conceptual, but fully coupled socio-hydrological models for selected sectors and regions. These models will be used to generate integrated scenarios of the climate and socio-economic change.

  17. MO-FG-202-04: Gantry-Resolved Linac QA for VMAT: A Comprehensive and Efficient System Using An Electronic Portal Imaging Device

    Energy Technology Data Exchange (ETDEWEB)

    Zwan, B J [Central Coast Cancer Centre, Gosford, NSW (Australia); University of Newcastle, Newcastle, NSW (Australia); Barnes, M; Greer, P B [University of Newcastle, Newcastle, NSW (Australia); Calvary Mater Hospital, Newcastle, NSW (Australia); Hindmarsh, J; Seymour, E [Central Coast Cancer Centre, Gosford, NSW (Australia); O’Connor, D J [University of Newcastle, Newcastle, NSW (Australia); Keall, P J [University of Sydney, Camperdown, NSW (Australia)

    2016-06-15

    Purpose: To automate gantry-resolved linear accelerator (linac) quality assurance (QA) for volumetric modulated arc therapy (VMAT) using an electronic portal imaging device (EPID). Methods: A QA system for VMAT was developed that uses an EPID, frame-grabber assembly and in-house developed image processing software. The system relies solely on the analysis of EPID image frames acquired without the presence of a phantom. Images were acquired at 8.41 frames per second using a frame grabber and ancillary acquisition computer. Each image frame was tagged with a gantry angle from the linac’s on-board gantry angle encoder. Arc-dynamic QA plans were designed to assess the performance of each individual linac component during VMAT. By analysing each image frame acquired during the QA deliveries the following eight machine performance characteristics were measured as a function of gantry angle: MLC positional accuracy, MLC speed constancy, MLC acceleration constancy, MLC-gantry synchronisation, beam profile constancy, dose rate constancy, gantry speed constancy, dose-gantry angle synchronisation and mechanical sag. All tests were performed on a Varian iX linear accelerator equipped with a 120 leaf Millennium MLC and an aS1000 EPID (Varian Medical Systems, Palo Alto, CA, USA). Results: Machine performance parameters were measured as a function of gantry angle using EPID imaging and compared to machine log files and the treatment plan. Data acquisition is currently underway at 3 centres, incorporating 7 treatment units, at 2 weekly measurement intervals. Conclusion: The proposed system can be applied for streamlined linac QA and commissioning for VMAT. The set of test plans developed can be used to assess the performance of each individual components of the treatment machine during VMAT deliveries as a function of gantry angle. The methodology does not require the setup of any additional phantom or measurement equipment and the analysis is fully automated to allow for

  18. Comprehensive geographic analysis of current photovoltaic industry in Slovakia, focusing on building systems; Komplexna geograficka analyza fotovoltickeho priemyslu na Slovensku so zameranim na pozemne systemy

    Energy Technology Data Exchange (ETDEWEB)

    Chovanec, M. [Univerzita Komenskeho, Prirodovedecka fakulta, Katedra regionalnej geografie, ochrany a planovania krajiny, 84215 Bratislava (Slovakia)

    2013-04-16

    Terrestrial photovoltaic power plants were built in Slovakia, only 1 and a half years, until legislative action this rapidly growing industry stopped. The largest concentration of these plants were built in districts that are along the border with Hungary. Terrestrial photovoltaic systems are evaluated in this work for spatial level by various indicators, as well as from the pedogeographic view, in which climatic regions and soil types, these plants are located. (authors)

  19. MO-FG-202-04: Gantry-Resolved Linac QA for VMAT: A Comprehensive and Efficient System Using An Electronic Portal Imaging Device

    International Nuclear Information System (INIS)

    Zwan, B J; Barnes, M; Greer, P B; Hindmarsh, J; Seymour, E; O’Connor, D J; Keall, P J

    2016-01-01

    Purpose: To automate gantry-resolved linear accelerator (linac) quality assurance (QA) for volumetric modulated arc therapy (VMAT) using an electronic portal imaging device (EPID). Methods: A QA system for VMAT was developed that uses an EPID, frame-grabber assembly and in-house developed image processing software. The system relies solely on the analysis of EPID image frames acquired without the presence of a phantom. Images were acquired at 8.41 frames per second using a frame grabber and ancillary acquisition computer. Each image frame was tagged with a gantry angle from the linac’s on-board gantry angle encoder. Arc-dynamic QA plans were designed to assess the performance of each individual linac component during VMAT. By analysing each image frame acquired during the QA deliveries the following eight machine performance characteristics were measured as a function of gantry angle: MLC positional accuracy, MLC speed constancy, MLC acceleration constancy, MLC-gantry synchronisation, beam profile constancy, dose rate constancy, gantry speed constancy, dose-gantry angle synchronisation and mechanical sag. All tests were performed on a Varian iX linear accelerator equipped with a 120 leaf Millennium MLC and an aS1000 EPID (Varian Medical Systems, Palo Alto, CA, USA). Results: Machine performance parameters were measured as a function of gantry angle using EPID imaging and compared to machine log files and the treatment plan. Data acquisition is currently underway at 3 centres, incorporating 7 treatment units, at 2 weekly measurement intervals. Conclusion: The proposed system can be applied for streamlined linac QA and commissioning for VMAT. The set of test plans developed can be used to assess the performance of each individual components of the treatment machine during VMAT deliveries as a function of gantry angle. The methodology does not require the setup of any additional phantom or measurement equipment and the analysis is fully automated to allow for

  20. A Comprehensive K2 and Ground-based Study of CRTS J035905.9+175034, an Eclipsing SU UMa System with a Large Mass Ratio

    Science.gov (United States)

    Littlefield, Colin; Garnavich, Peter; Kennedy, Mark; Szkody, Paula; Dai, Zhibin

    2018-06-01

    CRTS J035905.9+175034 is the first eclipsing SU UMa system for which a superoutburst has been observed by Kepler in the short-cadence mode. The light curve contains one superoutburst, eight normal outbursts (including a precursor to the superoutburst), and several minioutbursts that are present before—but not after—the superoutburst. The superoutburst began with a precursor normal outburst, and shortly after the peak of the precursor, the system developed large-amplitude superhumps that achieved their maximum amplitude after just three superhump cycles. The period excess of the initial superhump period relative to the orbital period implies a mass ratio of 0.281 ± 0.015, placing it marginally above most theoretical predictions of the highest-possible mass ratio for superhump formation. In addition, our analysis of the variations in eclipse width and depth, as well as the hot spot amplitudes, generally provides substantiation of the thermal-tidal instability model. The K2 data, in conjunction with our ground-based time-resolved spectroscopy and photometry from 2014 to 2016, allows us to determine many of the fundamental parameters of this system.

  1. Information basis for developing comprehensive waste management system-US-Japan joint nuclear energy action plan waste management working group phase I report.

    Energy Technology Data Exchange (ETDEWEB)

    Nutt, M.; Nuclear Engineering Division

    2010-05-25

    The activity of Phase I of the Waste Management Working Group under the United States - Japan Joint Nuclear Energy Action Plan started in 2007. The US-Japan JNEAP is a bilateral collaborative framework to support the global implementation of safe, secure, and sustainable, nuclear fuel cycles (referred to in this document as fuel cycles). The Waste Management Working Group was established by strong interest of both parties, which arise from the recognition that development and optimization of waste management and disposal system(s) are central issues of the present and future nuclear fuel cycles. This report summarizes the activity of the Waste Management Working Group that focused on consolidation of the existing technical basis between the U.S. and Japan and the joint development of a plan for future collaborative activities. Firstly, the political/regulatory frameworks related to nuclear fuel cycles in both countries were reviewed. The various advanced fuel cycle scenarios that have been considered in both countries were then surveyed and summarized. The working group established the working reference scenario for the future cooperative activity that corresponds to a fuel cycle scenario being considered both in Japan and the U.S. This working scenario involves transitioning from a once-through fuel cycle utilizing light water reactors to a one-pass uranium-plutonium fuel recycle in light water reactors to a combination of light water reactors and fast reactors with plutonium, uranium, and minor actinide recycle, ultimately concluding with multiple recycle passes primarily using fast reactors. Considering the scenario, current and future expected waste streams, treatment and inventory were discussed, and the relevant information was summarized. Second, the waste management/disposal system optimization was discussed. Repository system concepts were reviewed, repository design concepts for the various classifications of nuclear waste were summarized, and the factors

  2. Information basis for developing comprehensive waste management system. US-Japan joint nuclear energy action plan waste management working group phase I report (Joint research)

    International Nuclear Information System (INIS)

    Yui, Mikazu; Ishikawa, Hirohisa; Umeki, Hiroyuki; Hioki, Kazumasa; Naito, Morimasa; Makino, Hitoshi; Oda, Chie; Tachi, Yukio; Mitsui, Seiichiro; Shibata, Masahiro; Watanabe, Atsuo; Yoshino, Kyoji; Seo, Toshihiro; Miyamoto, Yoichi; Nutt, Mark; Peters, Mark; Bresee, James; Lesica, Sue; Schwab, Patrick; Gomberg, Steve; Jones, Jay; Halsey, Bill; Marra, John; Vienna, John; Gombert, Drik; McMahon, Kevin; James, Scott; Caporuscio, Florie

    2010-05-01

    The activity of Phase I of the Waste Management Working Group under the United States - Japan Joint Nuclear Energy Action Plan started in 2007. The US-Japan JNEAP is a bilateral collaborative framework to support the global implementation of safe, secure, and sustainable, nuclear fuel cycles (referred to in this document as fuel cycles). The Waste Management Working Group was established by strong interest of both parties, which arise from the recognition that development and optimization of waste management and disposal system(s) are central issues of the present and future nuclear fuel cycles. This report summarizes the activity of the Waste Management Working Group that focused on consolidation of the existing technical basis between the U.S. and Japan and the joint development of a plan for future collaborative activities. Firstly, the political/regulatory frameworks related to nuclear fuel cycles in both countries were reviewed. The various advanced fuel cycle scenarios that have been considered in both countries were then surveyed and summarized. The working group established the working reference scenario for the future cooperative activity that corresponds to a fuel cycle scenario being considered both in Japan and the U.S. This working scenario involves transitioning from a once-through fuel cycle utilizing light water reactors to a one-pass uranium-plutonium fuel recycle in light water reactors to a combination of light water reactors and fast reactors with plutonium, uranium, and minor actinide recycle, ultimately concluding with multiple recycle passes primarily using fast reactors. Considering the scenario, current and future expected waste streams, treatment and inventory were discussed, and the relevant information was summarized. Second, the waste management/disposal system optimization was discussed. Repository system concepts were reviewed, repository design concepts for the various classifications of nuclear waste were summarized, and the factors

  3. Comprehensive evaluation of a digital imaging network

    International Nuclear Information System (INIS)

    Mun, S.K.; Benson, H.; Elliott, L.P.; Horii, S.

    1988-01-01

    The authors' institution has installed a comprehensive PACS network involving a dozen work stations and ten imaging systems with electronic archiving and teleradiology capability based on the CommView (AT and T) system and its fiberoptic network. Diagnostic reporting stations are placed in neuroradiology, abdominal imaging, general radiology, and ultrasound service. Other review stations are located in intensive care units, radiation medicine, the emergency room, and other sites. Clinical acceptance of such technology varies depending on a number of factors: image quality, image data volume, service style, and personal preference. The general acceptance depends on the work station performance, network response time, and work station environment. Clinical acceptance by radiologists and referring physicians was evaluated. The evaluation project included work-station performance, network performance, system interface, RIS interface, and development of training methods and implementation strategy for other sites. A cost analysis and a study of administrative impact are integral parts of the comprehensive evaluation project

  4. FIELD TEST PROGRAM TO DEVELOP COMPREHENSIVE DESIGN, OPERATING AND COST DATA FOR MERCURY CONTROL SYSTEMS ON NON-SCRUBBED COAL-FIRED BOILERS

    International Nuclear Information System (INIS)

    C. Jean Bustard

    2001-01-01

    With the Nation's coal-burning utilities facing the possibility of tighter controls on mercury pollutants, the U.S. Department of Energy is funding projects that could offer power plant operators better ways to reduce these emissions at much lower costs. Mercury is known to have toxic effects on the nervous system of humans and wildlife. Although it exists only in trace amounts in coal, mercury is released when coal burns and can accumulate on land and in water. In water, bacteria transform the metal into methylmercury, the most hazardous form of the metal. Methylmercury can collect in fish and marine mammals in concentrations hundreds of thousands times higher than the levels in surrounding waters. One of the goals of DOE is to develop technologies by 2005 that will be capable of cutting mercury emissions 50 to 70 percent at well under one-half of today's costs. ADA Environmental Solutions (ADA-ES) is managing a project to test mercury control technologies at full scale at four different power plants from 2000 to 2003. The ADA-ES project is focused on those power plants that are not equipped with wet flue gas desulfurization systems. ADA-ES will develop a portable system that will be moved to four different utility power plants for field testing. Each of the plants is equipped with either electrostatic precipitators or fabric filters to remove solid particles from the plant's flue gas. ADA-ES's technology will inject a dry sorbent, such as fly ash or activated carbon, that removes the mercury and makes it more susceptible to capture by the particulate control devices. A fine water mist may be sprayed into the flue gas to cool its temperature to the range where the dry sorbent is most effective. PG and E National Energy Group is providing two test sites that fire bituminous coals and are both equipped with electrostatic precipitators and carbon/ash separation systems. Wisconsin Electric Power Company is providing a third test site that burns Powder River Basin (PRB

  5. FIELD TEST PROGRAM TO DEVELOP COMPREHENSIVE DESIGN, OPERATING AND COST DATA FOR MERCURY CONTROL SYSTEMS ON NON-SCRUBBED COAL-FIRED BOILERS

    International Nuclear Information System (INIS)

    C. Jean Bustard

    2002-01-01

    With the Nation's coal-burning utilities facing the possibility of tighter controls on mercury pollutants, the U.S. Department of Energy is funding projects that could offer power plant operators better ways to reduce these emissions at much lower costs. Mercury is known to have toxic effects on the nervous system of humans and wildlife. Although it exists only in trace amounts in coal, mercury is released when coal burns and can accumulate on land and in water. In water, bacteria transform the metal into methylmercury, the most hazardous form of the metal. Methylmercury can collect in fish and marine mammals in concentrations hundreds of thousands times higher than the levels in surrounding waters. One of the goals of DOE is to develop technologies by 2005 that will be capable of cutting mercury emissions 50 to 70 percent at well under one-half of today's costs. ADA Environmental Solutions (ADA-ES) is managing a project to test mercury control technologies at full scale at four different power plants from 2000-2003. The ADA-ES project is focused on those power plants that are not equipped with wet flue gas desulfurization systems. ADA-ES will develop a portable system that will be moved to four different utility power plants for field testing. Each of the plants is equipped with either electrostatic precipitators or fabric filters to remove solid particles from the plant's flue gas. ADA-ES's technology will inject a dry sorbent, such as fly ash or activated carbon, that removes the mercury and makes it more susceptible to capture by the particulate control devices. A fine water mist may be sprayed into the flue gas to cool its temperature to the range where the dry sorbent is most effective. PG and E National Energy Group is providing two test sites that fire bituminous coals and are both equipped with electrostatic precipitators and carbon/ash separation systems. Wisconsin Electric Power Company is providing a third test site that burns Powder River Basin (PRB

  6. FIELD TEST PROGRAM TO DEVELOP COMPREHENSIVE DESIGN, OPERATING AND COST DATA FOR MERCURY CONTROL SYSTEMS ON NON-SCRUBBED COAL-FIRED BOILERS

    International Nuclear Information System (INIS)

    C. Jean Bustard

    2001-01-01

    With the Nation's coal-burning utilities facing the possibility of tighter controls on mercury pollutants, the U.S. Department of Energy is funding projects that could offer power plant operators better ways to reduce these emissions at much lower costs. Mercury is known to have toxic effects on the nervous system of humans and wildlife. Although it exists only in trace amounts in coal, mercury is released when coal burns and can accumulate on land and in water. In water, bacteria transform the metal into methylmercury, the most hazardous form of the metal. Methylmercury can collect in fish and marine mammals in concentrations hundreds of thousands times higher than the levels in surrounding waters. One of the goals of DOE is to develop technologies by 2005 that will be capable of cutting mercury emissions 50 to 70 percent at well under one-half of today's costs. ADA Environmental Solutions (ADA-ES) is managing a project to test mercury control technologies at full scale at four different power plants from 2000-2003. The ADA-ES project is focused on those power plants that are not equipped with wet flue gas desulfurization systems. ADA-ES will develop a portable system that will be moved to four different utility power plants for field testing. Each of the plants is equipped with either electrostatic precipitators or fabric filters to remove solid particles from the plant's flue gas. ADA-ES's technology will inject a dry sorbent, such as fly ash or activated carbon, that removes the mercury and makes it more susceptible to capture by the particulate control devices. A fine water mist may be sprayed into the flue gas to cool its temperature to the range where the dry sorbent is most effective. PG and E National Energy Group is providing two test sites that fire bituminous coals and are both equipped with electrostatic precipitators and carbon/ash separation systems. Wisconsin Electric Power Company is providing a third test site that burns Powder River Basin coal

  7. FIELD TEST PROGRAM TO DEVELOP COMPREHENSIVE DESIGN, OPERATING AND COST DATA FOR MERCURY CONTROL SYSTEMS ON NON-SCRUBBED COAL-FIRED BOILERS

    International Nuclear Information System (INIS)

    C. Jean Bustard

    2001-01-01

    With the Nation's coal-burning utilities facing the possibility of tighter controls on mercury pollutants, the U.S. Department of Energy is funding projects that could offer power plant operators better ways to reduce these emissions at much lower costs. Mercury is known to have toxic effects on the nervous system of humans and wildlife. Although it exists only in trace amounts in coal, mercury is released when coal burns and can accumulate on land and in water. In water, bacteria transform the metal into methylmercury, the most hazardous form of the metal. Methylmercury can collect in fish and marine mammals in concentrations hundreds of thousands times higher than the levels in surrounding waters. One of the goals of DOE is to develop technologies by 2005 that will be capable of cutting mercury emissions 50 to 70 percent at well under one-half of today's costs. ADA Environmental Solutions (ADA-ES) is managing a project to test mercury control technologies at full scale at four different power plants from 2000-2003. The ADA-ES project is focused on those power plants that are not equipped with wet flue gas desulfurization systems. ADA-ES will develop a portable system that will be moved to four different utility power plants for field testing. Each of the plants is equipped with either electrostatic precipitators or fabric filters to remove solid particles from the plant's flue gas. ADA-ES's technology will inject a dry sorbent, such as fly ash or activated carbon, that removes the mercury and makes it more susceptible to capture by the particulate control devices. A fine water mist may be sprayed into the flue gas to cool its temperature to the range where the dry sorbent is most effective. PG and E National Energy Group is providing two test sites that fire bituminous coals and are both equipped with electrostatic precipitators and carbon/ash separation systems. Wisconsin Electric Power Company is providing a third test site that burns Powder River Basin (PRB

  8. Pragmatic Comprehension Development through Telecollaboration

    Science.gov (United States)

    Rafieyan, Vahid; Sharafi-Nejad, Maryam; Khavari, Zahra; Eng, Lin Siew; Mohamed, Abdul Rashid

    2014-01-01

    Pragmatic comprehension can be ideally developed through contact with target language speakers. This contact can be provided in English as Foreign Language contexts through telecollaboration. To test the actual effect of telecollaboration on the development of pragmatic comprehension, 30 Iranian undergraduates of English as a Foreign Language…

  9. Reading comprehension in Parkinson's disease.

    Science.gov (United States)

    Murray, Laura L; Rutledge, Stefanie

    2014-05-01

    Although individuals with Parkinson's disease (PD) self-report reading problems and experience difficulties in cognitive-linguistic functions that support discourse-level reading, prior research has primarily focused on sentence-level processing and auditory comprehension. Accordingly, the authors investigated the presence and nature of reading comprehension in PD, hypothesizing that (a) individuals with PD would display impaired accuracy and/or speed on reading comprehension tests and (b) reading performances would be correlated with cognitive test results. Eleven adults with PD and 9 age- and education-matched control participants completed tests that evaluated reading comprehension; general language and cognitive abilities; and aspects of attention, memory, and executive functioning. The PD group obtained significantly lower scores on several, but not all, reading comprehension, language, and cognitive measures. Memory, language, and disease severity were significantly correlated with reading comprehension for the PD group. Individuals in the early stages of PD without dementia or broad cognitive deficits can display reading comprehension difficulties, particularly for high- versus basic-level reading tasks. These reading difficulties are most closely related to memory, high-level language, and PD symptom severity status. The findings warrant additional research to delineate further the types and nature of reading comprehension impairments experienced by individuals with PD.

  10. A Comprehensive Child Development Program; Title XX, Final Report.

    Science.gov (United States)

    Whatley, Juanita T.

    This booklet describes the Comprehensive Child Day Care Program for the Atlanta Public School System, a Title XX Program. This program provided day care services for children of clients in various categories. The program goals for 1975-76 were geared toward providing comprehensive day care to encompass social services to the family and…

  11. Riddle Appreciation and Reading Comprehension in Cantonese-Speaking Children

    Science.gov (United States)

    Tang, Ivy N. Y.; To, Carol K. S.; Weekes, Brendan S.

    2013-01-01

    Purpose: Inference-making skills are necessary for reading comprehension. Training in riddle appreciation is an effective way to improve reading comprehension among English-speaking children. However, it is not clear whether these methods generalize to other writing systems. The goal of the present study was to investigate the relationship between…

  12. Comprehensive Auto CAD

    International Nuclear Information System (INIS)

    Jang, Taekju

    1993-06-01

    This book starts introduction of conception, application system, software for CAD, function of Auto CAD, kinds and function of Auto CAD files. It deals with starting of Auto CAD, dialogue box and Auto CAD interface, utility command, 2D drawing command, check command, control system, dimension, hatching command, layer command, block, 3D drawing, plotting and printing, auto CAD and application of data, supply program of auto CAD, AME and region modeler, EDLIN, script optimization of Auto CAD and composition on demand.

  13. Reforma integral para mejorar el desempeño del sistema de salud en México Comprehensive reform to improve health system performance in Mexico

    Directory of Open Access Journals (Sweden)

    Julio Frenk

    2007-01-01

    Full Text Available A pesar de haber alcanzado una esperanza de vida promedio de 75 años, similar a la de países más desarrollados, México ingresó al siglo XXI con un sistema de salud marcado por su incapacidad para ofrecer protección financiera en salud a más de la mitad de su población. Esto es resultado y causa de las desigualdades sociales que han caracterizado el proceso de desarrollo en México. Varias limitaciones estructurales han dificultado el funcionamiento y limitado el avance de su sistema de salud. Consciente de que la falta de protección financiera era su principal debilidad, México ha emprendido una reforma estructural para mejorar el desempeño del sistema de salud mediante el establecimiento del Sistema de Protección Social en Salud (SPSS, el cual ha introducido nuevas reglas de financiamiento e incentivos. La principal innovación de la reforma ha sido el Seguro Popular de Salud, el componente de aseguramiento del SPSS dirigido al financiamiento de la atención médica para todas aquellas familias, en su mayoría pobres, que históricamente habían sido excluidas de la seguridad social. La reforma ha permitido un incremento significativo en la inversión pública en salud, al tiempo que realinea los incentivos para garantizar una atención de mayor calidad técnica e interpersonal. En este trabajo se describen las principales características y los resultados iniciales de este esfuerzo de reforma de México, y se derivan algunas lecciones para otros países que consideren llevar a cabo transformaciones a su sistema de salud en circunstancias de desafío similares.Despite having achieved an average life expectancy of 75 years, much the same as that of more developed countries, Mexico entered the 21st century with a health system mared by its failure to offer financial protection in health to more than half of its citizens; this was both a result and a cause of the social inequalities that have marked the development process in Mexico

  14. Patient access to medicines in two countries with similar health systems and differing medicines policies: Implications from a comprehensive literature review.

    Science.gov (United States)

    Babar, Zaheer-Ud-Din; Gammie, Todd; Seyfoddin, Ali; Hasan, Syed Shahzad; Curley, Louise E

    2018-04-13

    Countries with similar health systems but different medicines policies might result in substantial medicines usage differences and resultant outcomes. The literature is sparse in this area. To review pharmaceutical policy research in New Zealand and Australia and discuss differences between the two countries and the impact these differences may have on subsequent medicine access. A review of the literature (2008-2016) was performed to identify relevant, peer-reviewed articles. Systematic searches were conducted across the six databases MEDLINE, PubMed, Science Direct, Springer Links, Scopus and Google Scholar. A further search of journals of high relevance was also conducted. Using content analysis, a narrative synthesis of pharmaceutical policy research influencing access to medicines in Australia and New Zealand was conducted. The results were critically assessed in the context of policy material available via grey literature from the respective countries. Key elements regarding pharmaceutical policy were identified from the 35 research papers identified for this review. Through a content analysis, three broad categories of pharmaceutical policy were found, which potentially could influence patient access to medicines in each country; the national health system, pricing and reimbursement. Within these three categories, 9 subcategories were identified: national health policy, pharmacy system, marketing authorization and regulation, prescription to non-prescription medicine switch, orphan drug policies, generic medicine substitution, national pharmaceutical schedule and health technology assessment, patient co-payment and managed entry agreements. This review systematically evaluated the current literature and identified key areas of difference in policy between Australia and NZ. Australia appears to cover and reimburse a greater number of medicines, while New Zealand achieves much lower prices for medicines than their Australian counterparts and has been more

  15. Training of ultra-fast speech comprehension induces functional reorganization of the central-visual system in late-blind humans

    Directory of Open Access Journals (Sweden)

    Susanne eDietrich

    2013-10-01

    Full Text Available Individuals suffering from vision loss of a peripheral origin may learn to understand spoken language at a rate of up to about 22 syllables (syl per seconds (s – exceeding by far the maximum performance level of untrained listeners (ca. 8 syl/s. Previous findings indicate the central-visual system to contribute to the processing of accelerated speech in blind subjects. As an extension, the present training study addresses the issue whether acquisition of ultra-fast (18 syl/s speech perception skills induces de novo central-visual hemodynamic activation in late-blind participants. Furthermore, we asked to what extent subjects with normal or residual vision can improve understanding of accelerated verbal utterances by means of specific training measures. To these ends, functional magnetic resonance imaging (fMRI was performed while subjects were listening to forward and reversed sentence utterances of moderately fast and ultra-fast syllable rates (8 or 18 syl/s prior to and after a training period of ca. six months. Four of six participants showed – independently from residual visual functions – considerable enhancement of ultra-fast speech perception (about 70 percentage points correctly repeated words whereas behavioral performance did not change in the two remaining participants. Only subjects with very low visual acuity displayed training-induced hemodynamic activation of the central-visual system. By contrast, participants with moderately impaired or even normal visual acuity showed, instead, increased right-hemispheric frontal or bilateral anterior temporal lobe responses after training. All subjects with significant training effects displayed a concomitant increase of hemodynamic activation of left-hemispheric SMA. In spite of similar behavioral performance, trained experts appear to use distinct strategies of ultra-fast speech processing depending on whether the occipital cortex is still deployed for visual processing.

  16. The FP7 collaborative project RECOSY - a comprehensive information management system for european disposal R and D (INMAN): a proposal for the next European framework program - 59397

    International Nuclear Information System (INIS)

    Buckau, Gunnar; ); Delos, Anne; Montoya, Vanessa

    2012-01-01

    Document available in abstract form only. Full text of publication follows: The Collaborative Project Redox phenomena Controlling Systems (RECOSY) started in 2008 falls within the EURATOM program and is implemented within the 7. Framework Program. The main objective of ReCosy is the sound understanding of redox phenomena controlling the long-term release/retention of radionuclides in nuclear waste disposal providing tools to apply the results to Performance Assessment/Safety Case. Although redox is not a new issue, different questions are still not resolved, such as, redox processes in the long-term dissolution/ chemical transformation of the radioactive waste, waste packages and engineered barriers, and migration in the far-field, including which species are formed and their respective various retention mechanisms. In order to solve this questions, the project includes i) development of advanced analytical tools, ii) investigations of processes responsible for redox control (thermodynamically and kinetically controlled processes, surface reactions and microbial processes), iii) provision of required data on redox controlling processes, and iv) response to internal/external disturbances in disposal systems to internal/external disturbances. The work program of the project is structured along six Research and Technological Development work-packages. Specific Work-packages on knowledge management, education and training (WP7) and administrative management issues (WP8) are also included in the project. In WP1, the scientific state-of-the-art and its application to Performance Assessment/Safety Case is documented and regularly up-dated, based on the safety case of the ANDRA B2 cell. WP2 deals with the development and testing of redox determination methods using different type of electrodes

  17. Comprehensive study of the abrasive wear and slurry erosion behavior of an expanded system of high chromium cast iron and microstructural modification for enhanced wear resistance

    Science.gov (United States)

    Chung, Reinaldo Javier

    High chromium cast irons (HCCIs) have been demonstrated to be an effective material for a wide range of applications in aggressive environments, where resistances to abrasion, erosion and erosion-corrosion are required. For instance, machinery and facilities used in mining and extraction in Alberta's oil sands suffer from erosion and erosion-corrosion caused by silica-containing slurries, which create challenges for the reliability and maintenance of slurry pumping systems as well as other processing and handling equipment. Considerable efforts have been made to determine and understand the relationship between microstructural features of the HCCIs and their wear performance, in order to guide the material selection and development for specific service conditions with optimal performance. The focus was previously put on a narrow group of compositions dictated by ASTM A532. However, with recent advances in casting technology, the HCCI compositional range can be significantly expanded, which potentially brings new alloys that can be superior to those which are currently employed. This work consists of three main aspects of study. The first one is the investigation of an expanded system of white irons with their composition ranging from 1 to 6 wt.% C and 5 to 45 wt.% Cr, covering 53 alloys. This work has generated wear and corrosion maps and established correlation between the performance and microstructural features for the alloys. The work was conducted in collaboration with the Materials Development Center of Weir Minerals in Australia, and the results have been collected in a database that is used by the company to guide materials selection for slurry pump components in Alberta oil sands and in other mining operations throughout the world. The second part consists of three case studies on effects of high chromium and high carbon, respectively, on the performance of the HCCIs. The third aspect is the development of an approach to enhance the wear resistance of

  18. Experience in the Use of Psychocorrection Therapy in the Comprehensive Treatment of Patients with Gastroesophageal Reflux Disease Combined with Dysfunction of the Biliary System

    Directory of Open Access Journals (Sweden)

    L.V. Demeshkina

    2016-09-01

    Full Text Available Nowadays, due to the rapid increase in the number of stress factors, it is especially important to use psychotherapy and psychopharmacotherapy in the combination treatment of patients with diseases of the gastrointestinal tract. Psychogenic overlaying plays a leading role in the clinical picture of the disease and determines the decreased performance in patients. Objective. To evaluate the effectiveness of therapy with psychocorrective agents in patients with gastroesophageal reflux disease (GERD associated with dysfunction of the biliary system, if they have depressive and anxiety symptoms. Materials and methods. All patients were divided into 2 groups: group I consisted of 27 patients, who received only basic combination treatment, group II — of 25 patients, who in addition to the basic treatment received thioridazine, which is a piperidine derivative of phenothiazine and belongs to the group of neuroleptics. Both groups were representative by the age, duration and course of the disease. All patients demonstrate anxiety and depressive symptoms on the HADS scale. Questionnaire SF‑36 was used to analyze the quality of life. Treatment efficacy was assessed 14 days after. Results. As a result of the treatment, an improvement in overall well-being was observed in both groups against the background of reduction in the pain and dyspeptic syndromes. Additional prescription of psychocorrectives (thioridazine to the basic therapy results in greater positive changes in the intensity of anxiety and depressive symptoms. The distribution of patients by the level of anxiety and depression after treatment showed that these indicators were absent more often in group II (by 2.6 and 1.5 times, respectively. However, cases of clinically significant anxiety and depression were 4.6 and 3.7 times more often in patients, who did not receive thioridazine. The difference in points between the level of anxiety and depression before and after the treatment was 4

  19. Probing dynamic hydrologic system of slowly-creeping landslides with passive seismic imaging: A comprehensive landslide monitoring site at Lantai, Ilan area in Taiwan

    Science.gov (United States)

    Huang, H. H.; Hsu, Y. J.; Kuo, C. Y.; Chen, C. C.; Kuo, L. W.; Chen, R. F.; Lin, C. R.; Lin, P. P.; Lin, C. W.; Lin, M. L.; Wang, K. L.

    2017-12-01

    A unique landslide monitoring project integrating multidisciplinary geophysics experiments such as GPS, inclinometer, piezometer, and spontaneous potential log has been established at Lantai, Ilan area to investigating the possible detachment depth range and the physical mechanism of a slowly creeping landslide. In parallel with this, a lately deployed local seismic network also lends an opportunity to employ the passive seismic imaging technique to detect the time-lapse changes of seismic velocity in and around the landslide area. Such technique that retrieves Green's functions by cross-correlation of continuous ambient noise has opened new opportunities to seismologically monitoring the environmental and tectonic events such as ground water variation, magma intrusion under volcanos, and co-seismic medium damage in recent years. Integrating these geophysical observations, we explore the primary controls of derived seismic velocity changes and especially the hydrological response of the landslide to the passage of Megi typhoon in the last September 2016, which could potentially further our understanding of the dynamic system of landslides and in turn help the hazard mitigation.

  20. [Development and Implementation of a Comprehensive Health Management System (Fit for Work and Life) for Employees of a University Hospital - A Practice Report].

    Science.gov (United States)

    Gutenbrunner, C; Egen, C; Kahl, K G; Briest, J; Tegtbur, U; Miede, J; Born, M

    2017-07-01

    Background: Due to the increase of sick leave, prolonging working life and the prediction of shortage of skilled workers in the future, health management systems are continuously gaining importance. Employees in a University Hospital are exposed to particular stress factors, which are also reflected in a higher than average amount of sick leave. Against this background, the project "Fit for Work and Life" (FWL) was developed and implemented by the Hannover Medical School (MHH). Aims: FWL aims to maintain, improve or recover the work ability of employees by offering both preventive and rehabilitative treatments. A second goal is to significantly reduce the days of sick leave. Methods: The project was jointly developed and implemented by five MHH departments and the DRV Braunschweig-Hannover (DRV BS-H) according to previously defined principles. It was scientifically evaluated by the following outcomes: average days of sick leave, work ability (WAI), quality of life (SF-36, WHOQOL), coping strategies (FERUS) and effort-reward imbalance (ERI). Results and Conclusions: So far, this project is unique in its concept. It has been successfully implemented in the organisational structures of the MHH. 376 employees have registered during the first project year. Up to now, 182 participants have completed their individual programmes. The results show that 60.4% of employees have moderate to poor WAI values. The average of the mental summary scale of the SF-36 was 44.9, indicating a high workload. © Georg Thieme Verlag KG Stuttgart · New York.

  1. Model aerodynamic test results for two variable cycle engine coannular exhaust systems at simulated takeoff and cruise conditions. Comprehensive data report. Volume 2: Tabulated aeroynamic data book 1

    Science.gov (United States)

    Nelson, D. P.

    1981-01-01

    Tabulated data from wind tunnel tests conducted to evaluate the aerodynamic performance of an advanced coannular exhaust nozzle for a future supersonic propulsion system are presented. Tests were conducted with two test configurations: (1) a short flap mechanism for fan stream control with an isentropic contoured flow splitter, and (2) an iris fan nozzle with a conical flow splitter. Both designs feature a translating primary plug and an auxiliary inlet ejector. Tests were conducted at takeoff and simulated cruise conditions. Data were acquired at Mach numbers of 0, 0.36, 0.9, and 2.0 for a wide range of nozzle operating conditions. At simulated supersonic cruise, both configurations demonstrated good performance, comparable to levels assumed in earlier advanced supersonic propulsion studies. However, at subsonic cruise, both configurations exhibited performance that was 6 to 7.5 percent less than the study assumptions. At takeoff conditions, the iris configuration performance approached the assumed levels, while the short flap design was 4 to 6 percent less. Data are provided through test run 25.

  2. Novel integrated mechanical biological chemical treatment (MBCT) systems for the production of levulinic acid from fraction of municipal solid waste: A comprehensive techno-economic analysis.

    Science.gov (United States)

    Sadhukhan, Jhuma; Ng, Kok Siew; Martinez-Hernandez, Elias

    2016-09-01

    This paper, for the first time, reports integrated conceptual MBCT/biorefinery systems for unlocking the value of organics in municipal solid waste (MSW) through the production of levulinic acid (LA by 5wt%) that increases the economic margin by 110-150%. After mechanical separation recovering recyclables, metals (iron, aluminium, copper) and refuse derived fuel (RDF), lignocelluloses from remaining MSW are extracted by supercritical-water for chemical valorisation, comprising hydrolysis in 2wt% dilute H2SO4 catalyst producing LA, furfural, formic acid (FA), via C5/C6 sugar extraction, in plug flow (210-230°C, 25bar, 12s) and continuous stirred tank (195-215°C, 14bar, 20min) reactors; char separation and LA extraction/purification by methyl isobutyl ketone solvent; acid/solvent and by-product recovery. The by-product and pulping effluents are anaerobically digested into biogas and fertiliser. Produced biogas (6.4MWh/t), RDF (5.4MWh/t), char (4.5MWh/t) are combusted, heat recovered into steam generation in boiler (efficiency: 80%); on-site heat/steam demand is met; balance of steam is expanded into electricity in steam turbines (efficiency: 35%). Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. pyBSM: A Python package for modeling imaging systems

    Science.gov (United States)

    LeMaster, Daniel A.; Eismann, Michael T.

    2017-05-01

    There are components that are common to all electro-optical and infrared imaging system performance models. The purpose of the Python Based Sensor Model (pyBSM) is to provide open source access to these functions for other researchers to build upon. Specifically, pyBSM implements much of the capability found in the ERIM Image Based Sensor Model (IBSM) V2.0 along with some improvements. The paper also includes two use-case examples. First, performance of an airborne imaging system is modeled using the General Image Quality Equation (GIQE). The results are then decomposed into factors affecting noise and resolution. Second, pyBSM is paired with openCV to evaluate performance of an algorithm used to detect objects in an image.

  4. Hepatobiliary transit times of gadoxetate disodium (Primovist) for protocol optimization of comprehensive MR imaging of the biliary system-What is normal?

    Energy Technology Data Exchange (ETDEWEB)

    Ringe, Kristina I., E-mail: ringe.kristina@mh-hannover.de [Duke University Medical Center, Department of Radiology, Box 3808, Durham, NC 27710 (United States); Hannover Medical School, Department of Radiology, Carl-Neuberg Str. 1, 30625 Hannover (Germany); Husarik, Daniela B., E-mail: danielahusarik@yahoo.com [Duke University Medical Center, Department of Radiology, Box 3808, Durham, NC 27710 (United States); Gupta, Rajan T., E-mail: rajan.gupta@duke.edu [Duke University Medical Center, Department of Radiology, Box 3808, Durham, NC 27710 (United States); Boll, Daniel T., E-mail: daniel.boll@duke.edu [Duke University Medical Center, Department of Radiology, Box 3808, Durham, NC 27710 (United States); Merkle, Elmar M., E-mail: elmar.merkle@duke.edu [Duke University Medical Center, Department of Radiology, Box 3808, Durham, NC 27710 (United States)

    2011-08-15

    Objective: The purpose of this study was to determine transit times for excretion of Gd-EOB-DTPA into different segments of the hepatobiliary system in patients with normal liver function. Methods: This retrospective study was IRB approved with a waiver of consent granted. 61 patients (39 female, 22 male, mean age 52.5 years) with normal liver and renal function who underwent contrast enhanced hepatic MRI after injection of 10 mLGd-EOB-DTPA at 1.5 T and 3 T were included. Two readers evaluated all delayed images (3-20 min post contrast) for the presence of contrast agent in the intrahepatic bile ducts (IBD), the common bile duct (CBD), the gallbladder and the duodenum. A two-tailed, unpaired Student's t-test with p < 0.05 deemed significant was used to determine whether transit times were affected by patient gender, age or body mass index. Results: 20 min after contrast initiation, Gd-EOB-DTPA could be detected in the IBD and the CBD in all patients (100%); gallbladder reflux was visible in 53 (86.9%), duodenal excretion in 40 patients (65.5%), respectively. Mean transit times for contrast appearance in the various segments were as follows: IBD 12 min 13 s; CBD 12 min 27 s; gallbladder 13 min 32 s. Transit times were not significantly affected by patient gender, age or BMI. Conclusion: Within 20 min post contrast initiation, Gd-EOB-DTPA can be expected in the IBD and the CBD in patients with normal liver function. However, functional information about the sphincter Oddi complex can be ascertained only in about two thirds of these patients within this timeframe.

  5. Comprehensive approach to diabetic nephropathy

    Directory of Open Access Journals (Sweden)

    Bancha Satirapoj

    2014-09-01

    Full Text Available Diabetic nephropathy (DN is a leading cause of mortality and morbidity in patients with diabetes. This complication reflects a complex pathophysiology, whereby various genetic and environmental factors determine susceptibility and progression to end-stage renal disease. DN should be considered in patients with type 1 diabetes for at least 10 years who have microalbuminuria and diabetic retinopathy, as well as in patients with type 1 or type 2 diabetes with macroalbuminuria in whom other causes for proteinuria are absent. DN may also present as a falling estimated glomerular filtration rate with albuminuria as a minor presenting feature, especially in patients taking renin–angiotensin–aldosterone system inhibitors (RAASi. The pathological characteristic features of disease are three major lesions: diffuse mesangial expansion, diffuse thickened glomerular basement membrane, and hyalinosis of arterioles. Functionally, however, the pathophysiology is reflected in dysfunction of the mesangium, the glomerular capillary wall, the tubulointerstitium, and the vasculature. For all diabetic patients, a comprehensive approach to management including glycemic and hypertensive control with RAASi combined with lipid control, dietary salt restriction, lowering of protein intake, increased physical activity, weight reduction, and smoking cessation can reduce the rate of progression of nephropathy and minimize the risk for cardiovascular events. This review focuses on the latest published data dealing with the mechanisms, diagnosis, and current treatment of DN.

  6. CEDR: Comprehensive Epidemiologic Data Resource

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    The Department of Energy (DOE) and its predecessor agencies have a long history of epidemiologic research programs. The main focus of these programs has been the Health and Mortality Study of the DOE work force. This epidemiologic study began in 1964 with a feasibility study of workers at the Hanford facility. Studies of other populations exposed to radiation have also been supported, including the classic epidemiologic study of radium dial painters and studies of atomic bomb survivors. From a scientific perspective, these epidemiologic research program have been productive, highly credible, and formed the bases for many radiological protection standards. Recently, there has been concern that, although research results were available, the data on which these results were based were not easily obtained by interested investigators outside DOE. Therefore, as part of an effort to integrate and broaden access to its epidemiologic information, the DOE has developed the Comprehensive Epidemiologic Data Resource (CEDR) Program. Included in this effort is the development of a computer information system for accessing the collection of CEDR data and its related descriptive information. The epidemiologic data currently available through the CEDAR Program consist of analytic data sets, working data sets, and their associated documentation files. In general, data sets are the result of epidemiologic studies that have been conducted on various groups of workers at different DOE facilities during the past 30 years.

  7. Collaborative action for person-centred coordinated care (P3C): an approach to support the development of a comprehensive system-wide solution to fragmented care.

    Science.gov (United States)

    Lloyd, Helen M; Pearson, Mark; Sheaff, Rod; Asthana, Sheena; Wheat, Hannah; Sugavanam, Thava Priya; Britten, Nicky; Valderas, Jose; Bainbridge, Michael; Witts, Louise; Westlake, Debra; Horrell, Jane; Byng, Richard

    2017-11-22

    Fragmented care results in poor outcomes for individuals with complexity of need. Person-centred coordinated care (P3C) is perceived to be a potential solution, but an absence of accessible evidence and the lack of a scalable 'blue print' mean that services are 'experimenting' with new models of care with little guidance and support. This paper presents an approach to the implementation of P3C using collaborative action, providing examples of early developments across this programme of work, the core aim of which is to accelerate the spread and adoption of P3C in United Kingdom primary care settings. Two centrally funded United Kingdom organisations (South West Collaboration for Leadership in Applied Health Research and Care and South West Academic Health Science Network) are leading this initiative to narrow the gap between research and practice in this urgent area of improvement through a programme of service change, evaluation and research. Multi-stakeholder engagement and co-design are core to the approach. A whole system measurement framework combines outcomes of importance to patients, practitioners and health organisations. Iterative and multi-level feedback helps to shape service change while collecting practice-based data to generate implementation knowledge for the delivery of P3C. The role of the research team is proving vital to support informed change and challenge organisational practice. The bidirectional flow of knowledge and evidence relies on the transitional positioning of researchers and research organisations. Extensive engagement and embedded researchers have led to strong collaborations across the region. Practice is beginning to show signs of change and data flow and exchange is taking place. However, working in this way is not without its challenges; progress has been slow in the development of a linked data set to allow us to assess impact innovations from a cost perspective. Trust is vital, takes time to establish and is dependent on the

  8. Report on the results of the FY 1998 hydrogen utilization international clean energy system technology (WE-NET). Subtask 1. Survey/research for the comprehensive evaluation and developmental plan; 1998 nendo suiso riyo kokusai clean energy system gijutsu (WE-NET). 1. Sogo hyoka to kaihatsu keikaku no tame no chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The paper described the results of the FY 1998 WE-NET project survey. WE-NET is composed of various element technologies such as hydrogen production, hydrogen transportation, storage technology, low-temperature materials, hydrogen utilization, and hydrogen combustion turbine technology. Therefore, considering the effectiveness as a total system, it is extremely important to traversally evaluate the situation of the R and D of each technology and developmental achievements and to work out developmental plans with integration, considering the effectiveness as a total system. From viewpoints of making effective promotion of the project and attempting optimization as a total system, it is necessary to make organic/comprehensive connection and adjustment among individual subtasks all the time. In this survey/research, in the case of proceeding with the above-mentioned studies, a committee having knowledgeable persons and learned persons as members was established. There, an investigational study was conducted over the whole WE-NET structural technology, and at the same time the following were attempted: the constant/mobile comprehensive adjustment of the whole project, evaluation of the developmental results, and optimization of the developmental plans. The results obtained in 6 years of Period I were evaluated traversally and comprehensively, and how to proceed with the development in Period II was proposed, which showed the developmental continuity. (NEDO)

  9. The association between metabolic syndrome and its components with systemic lupus erythematosus: a comprehensive systematic review and meta-analysis of observational studies.

    Science.gov (United States)

    Hallajzadeh, J; Khoramdad, M; Izadi, N; Karamzad, N; Almasi-Hashiani, A; Ayubi, E; Qorbani, M; Pakzad, R; Sullman, M J M; Safiri, S

    2018-01-01

    Objectives Based upon inflammatory-related factors in chronic systemic lupus erythematosus (SLE), as well as the long-term prescription of corticosteroids, metabolic syndrome (MetS) prevalence is expected to be higher in SLE patients than among those without SLE. The aim of this study was to systematically analyze: (1) the worldwide prevalence of MetS in patients with SLE using different criteria, (2) the risk of MetS in patients with SLE compared with those without SLE, and (3) the risk of MetS component in patients with SLE compared with healthy controls. Methods We searched international databases, such as: Web of Science, Medline, PubMed, Scopus, Embase, CABI, CINAHL, DOAJ and Google Scholar. The articles which reported the prevalence of MetS in SLE patients, between 2006 and 2017, were included in the study if they had a: clear study design, study time and location, sound sampling approach and appropriate statistical analyses. Studies without sufficient data to determine the prevalence of MetS were excluded. Also, studies in patients suffering from other clinical diseases were not included. Results The meta-analyses of the prevalence (40 studies ( n = 6085)) and risk (20 studies ( n = 2348)) of MetS in SLE patients were conducted separately. The pooled prevalence of MetS among SLE patients was found to be 26% (95% confidence interval (CI): 22-30%), but varied from 18% (95% CI: 11-25%) to 34% (95% CI: 25-42%), depending upon the diagnostic criteria used. The overall pooled odds ratio (OR) of MetS in SLE patients, compared with healthy controls, was (OR = 2.50; 95% CI: 1.86-3.35), but this ranged from (OR = 1.23; 95% CI: 0.61-2.49) to (OR = 10.71; 95% CI: 1.33-86.48), depending upon the criteria used. Also, the risk of high fasting blood sugar (FBS; OR = 1.59; 95% CI: 1.05-2.40), low high-density lipoprotein cholesterol (HDL-C; OR = 1.43; 95% CI: 1.02-2.01), high blood pressure (BP; OR = 2.76; 95% CI: 2.19-3.47), high

  10. Comprehensive Error Rate Testing (CERT)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Centers for Medicare and Medicaid Services (CMS) implemented the Comprehensive Error Rate Testing (CERT) program to measure improper payments in the Medicare...

  11. A fuzzy comprehensive evaluation and entropy weight decision ...

    African Journals Online (AJOL)

    user

    With the rapid development of the Chinese electric power industry, the ... local dispatching centers, but the security of the power system will a major concern. ... reliability, security and economy have been used for the comprehensive and ...

  12. [Comprehension of hazard pictograms of chemical products among cleaning workers].

    Science.gov (United States)

    Martí Fernández, Francesc; van der Haar, Rudolf; López López, Juan Carlos; Portell, Mariona; Torner Solé, Anna

    2015-01-01

    To assess the comprehension among cleaning workers of the hazard pictograms as defined by the Globally Harmonized System (GHS) of the United Nations, concerning the classification, labeling and packaging of substances and mixtures. A sample of 118 workers was surveyed on their perception of the GHS hazard pictograms. Comprehensibility was measured by the percentage of correct answers and the degree to which they reflected International Organization for Standardization and American National Standards Institute standards for minimum level of comprehension. The influence of different variables to predict comprehension capacity was assessed using a logistic regression model. Three groups of pictograms could be distinguished which were statistically differentiated by their comprehensibility. Pictograms reflecting "acute toxicity" and "flammable", were described correctly by 94% and 95% of the surveyed population, respectively. For pictograms reflecting "systemic toxicity", "corrosive", "warning", "environment" and "explosive" the frequency of correct answers ranged from 48% to 64%, whereas those for pictograms "oxidizing" and "compressed gas" were interpreted correctly by only 7% of respondents. Prognostic factors for poor comprehension included: not being familiar with the pictograms, not having received training on safe use of chemical products, being an immigrant and being 54 years of age or older. Only two pictograms exceeded minimum standards for comprehension. Training, a tool proven to be effective to improve the correct interpretation of danger symbols, should be encouraged, especially in those groups with greater comprehension difficulties. Copyright belongs to the Societat Catalana de Salut Laboral.

  13. Thinking Systemically: Steps for States to Improve Equity in the Distribution of Teachers-- An Action-Planning Workbook to Help Guide Regional Comprehensive Center and State Education Agency Conversation to Address the Inequitable Distribution of Teachers

    Science.gov (United States)

    National Comprehensive Center for Teacher Quality, 2009

    2009-01-01

    The National Comprehensive Center for Teacher Quality (TQ Center) is a resource to which the regional comprehensive centers, states, and other education stakeholders turn for strengthening the quality of teaching--especially in high-poverty, low-performing, and hard-to-staff schools--and for finding guidance in addressing specific needs, thereby…

  14. Study on comprehensive evaluation model for nuclear power plant control room layout

    International Nuclear Information System (INIS)

    Zhu Yiming; Liu Yuan; Fan Huixian

    2010-01-01

    A comprehensive evaluation model for layout of the main control room of nuclear power plants was proposed. Firstly the design scope and principle for the layout of the main control room were defined based on the standards, and then the index system for the comprehensive evaluation was established. Finally, comprehensive evaluation was carried out for the layout design by applying the fuzzy comprehensive evaluation method in the index system. (authors)

  15. Estudo normativo do sistema compreensivo do Rorschach para a cidade de São Paulo A normative research on the Rorschach comprehensive system in the city of São Paulo

    Directory of Open Access Journals (Sweden)

    Regina Sonia Gattas F. do Nascimento

    2002-12-01

    Full Text Available O método de Rorschach tem se mostrado bastante eficiente como instrumento na área de investigação e diagnóstico da personalidade. O sistema compreensivo de Exner tem garantido ao Rorschach status de instrumento de grande confiabilidade, por sua objetividade e precisão nos resultados. Entretanto, para que isso ocorra, é necessário trabalhar com normas apropriadas para a população. Por isso, realizamos uma pesquisa de normatização a fim de encontrar resultados para melhor utilização do sistema compreensivo em nosso meio. Aplicamos o Rorschach individualmente, em 200 sujeitos não-pacientes, de ambos os sexos, residentes na cidade de São Paulo, com idade variando entre 17 e 65 anos, de todos os graus de escolaridade e níveis socioeconômicos. Os resultados apresentam várias diferenças, quando comparados às normas apresentadas por Exner, mas algumas semelhanças com os estudos apresentados por especialistas de outros países, especialmente, os de origem latina. Estes resultados indicam influências culturais em diversas variáveis do Rorschach.The Rorschach method has proven quite efficient as an instrument for personality investigation and diagnosis. Comprehensive system has guaranteed the Rorschach the status of an instrument of great reliability because of its objectivity and the precision of its results. However, for this to occur, it is necessary to work with appropriate norms for a population. So, we carried out a normalization study in order to find results for the better utilization of the comprehensive system in our milieu. The Rorschach was applied individually in 200 non-patient subjects of both sexes, residents of the City of São Paulo, ages ranging from 17 to 65, of all levels of education and socio-economic classes. The results show differences when compared to Exner’s norms, but similarities to studies presented by specialists in other countries, especially those of a Latin origin. These results indicate the

  16. A Python extension to the ATLAS online software for the thin gap chamber trigger system

    CERN Document Server

    Maeno, Tadashi; Komatsu, Satoru; Nakayoshi, Kazuo; Yasu, Yoshiji

    2004-01-01

    A Python extension module for A Toroidal LHC Apparatus (ATLAS) Online Software has been developed for the Thin Gap Chamber (TGC) trigger system. Python is an interactive scripting language including built- in high-level libraries, and provides an easy way to build Web applications. These features are not included in the Online Software, and are important in developing test software for the TGC trigger system. The Python extension module is designed and implemented using a C++ library, "Boost.Python." We have developed a Web application using the extension module and Zope (a Python-based Web application server), which allows one to monitor the TGC trigger system from anywhere in the world. The functionalities of the Python extension module and its application for the TGC trigger system are presented. 7 Refs.

  17. Comprehensive benefit analysis of regional water resources based on multi-objective evaluation

    Science.gov (United States)

    Chi, Yixia; Xue, Lianqing; Zhang, Hui

    2018-01-01

    The purpose of the water resources comprehensive benefits analysis is to maximize the comprehensive benefits on the aspects of social, economic and ecological environment. Aiming at the defects of the traditional analytic hierarchy process in the evaluation of water resources, it proposed a comprehensive benefit evaluation of social, economic and environmental benefits index from the perspective of water resources comprehensive benefit in the social system, economic system and environmental system; determined the index weight by the improved fuzzy analytic hierarchy process (AHP), calculated the relative index of water resources comprehensive benefit and analyzed the comprehensive benefit of water resources in Xiangshui County by the multi-objective evaluation model. Based on the water resources data in Xiangshui County, 20 main comprehensive benefit assessment factors of 5 districts belonged to Xiangshui County were evaluated. The results showed that the comprehensive benefit of Xiangshui County was 0.7317, meanwhile the social economy has a further development space in the current situation of water resources.

  18. Report on achievements in fiscal 1999. Development of technology to put photovoltaic power generation system for industrial use into practical use (Summary of comprehensive achievement); 1999 nendo sangyoyonado solar system jitsuyoka gijutsu kaihatsu seika hokokusho. Kenkyu kaihatsu kanri

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-09-01

    NEDO is proceeding with the development of a technology to put photovoltaic power generation system for industrial use into practical use, with an aim of simultaneous solution of sustainable growth and environmental problems. In developing an advanced heat process type system, selection was made on high-performance refrigeration materials for a stand-alone type refrigeration system capable of dealing with levels of minus 20 degrees C or lower (Ti-Ni-Zr-Mn-V based hydrogen absorbing alloys for use at low temperatures, and La-Ni-Sn-Al based hydrogen absorbing alloys for regeneration use). Evaluations were given on the developed refrigeration system by using the dynamic property simulation technology. The developed system achieved a cold heat acquiring temperature of minus 20 degrees or lower, and a heat output of 1,500 kcal/hr or more under the conditions of outside air temperature of 28 degrees C, and collected solar heat temperature of 140 degrees C. CO2 reduction unit requirement was calculated from LCA on a solar heat utilization system with which the future technological development is expected to aim at. Themes proposed to be promoted in the future would include a direct heat utilization system such as the building material integrated system, a freezing and refrigeration system, a high-temperature light and heat collecting system, a harmful substance analyzing system, a high temperature utilizing fuel synthesizing system, a high-efficiency heat storing system, and a snowy cold region system. (NEDO)

  19. (Context comprehension in digital social media

    Directory of Open Access Journals (Sweden)

    Alana Kercia Barros Demétrio

    2016-10-01

    Full Text Available In this article, we address the reading issue from the point of view of complexity. Understanding, according to Beaugrande (1997, that the text is a communicative event whose configuration involves elements of different nature, including the participants of interaction, we think that traditional approaches to reading, even those which are focused on interaction, do not satisfactorily bolster comprehension of this phenomenon. In order to analyze how aspects that characterize reading as a complex activity show at (context comprehension in digital social media, we leaned on the articles by Pellanda (2005 and by Franco (2011 and we were supported by the autopoietic theory by Maturana and Varela (1995, as well as by the concepts of emergency and incorporation by Hanks (2008. Through the analysis of two examples of interaction conveyed in virtual environment, we observed that reading triggers readers’ autopoiesis as living systems.

  20. Comprehensive analysis of transport aircraft flight performance

    Science.gov (United States)

    Filippone, Antonio

    2008-04-01

    This paper reviews the state-of-the art in comprehensive performance codes for fixed-wing aircraft. The importance of system analysis in flight performance is discussed. The paper highlights the role of aerodynamics, propulsion, flight mechanics, aeroacoustics, flight operation, numerical optimisation, stochastic methods and numerical analysis. The latter discipline is used to investigate the sensitivities of the sub-systems to uncertainties in critical state parameters or functional parameters. The paper discusses critically the data used for performance analysis, and the areas where progress is required. Comprehensive analysis codes can be used for mission fuel planning, envelope exploration, competition analysis, a wide variety of environmental studies, marketing analysis, aircraft certification and conceptual aircraft design. A comprehensive program that uses the multi-disciplinary approach for transport aircraft is presented. The model includes a geometry deck, a separate engine input deck with the main parameters, a database of engine performance from an independent simulation, and an operational deck. The comprehensive code has modules for deriving the geometry from bitmap files, an aerodynamics model for all flight conditions, a flight mechanics model for flight envelopes and mission analysis, an aircraft noise model and engine emissions. The model is validated at different levels. Validation of the aerodynamic model is done against the scale models DLR-F4 and F6. A general model analysis and flight envelope exploration are shown for the Boeing B-777-300 with GE-90 turbofan engines with intermediate passenger capacity (394 passengers in 2 classes). Validation of the flight model is done by sensitivity analysis on the wetted area (or profile drag), on the specific air range, the brake-release gross weight and the aircraft noise. A variety of results is shown, including specific air range charts, take-off weight-altitude charts, payload-range performance