Investigations and calculations toward increasing the efficiency of muon catalyzed fusion

International Nuclear Information System (INIS)

Monkhorst, H.J.

1989-11-01

A brief summary of results during this report period is given. Some of the topics investigated includes: (1) calculations of sticking fractions and d-t fusion from dtμ(JV) states, (2) ddμ sticking fractions, (3) the reactivation coefficient in d-t fusion, (4) fusion rates for all XYμ(JV)(JV=0,1), (5) nuclear effects on energy shifts and fusion rates for (J=O) states of dtμ, (6) and some comments on cold fusion

Study of fusion reactions forming Cf nuclei

International Nuclear Information System (INIS)

Khuyagbaatar, J.; Hinde, D. J.; Du Rietz, R.; Carter, I. P.; Dasgupta, M.; Duellmann, C. E.; Evers, M.; Wakhle, A.; Williams, E.; Yakushev, A.

2013-01-01

The formation of a compound nucleus in different projectile and target combinations is a powerful method for investigating the fusion process. Recently, the dominance of quasi-fission over fusion-fission has been inferred for 34 S+ 208 Pb in comparison to 36 S+ 206 Pb; both reactions lead to the compound nucleus 242 Cf*.The mass and angle distributions of the fission fragments from these reactions were studied in order to further investigate the presence of quasi-fission. (authors)

Complex fragment emission from hot compound nuclei

International Nuclear Information System (INIS)

Moretto, L.G.

1986-03-01

The experimental evidence for compound nucleus emission of complex fragments at low energies is used to interpret the emission of the same fragments at higher energies. The resulting experimental picture is that of highly excited compound nuclei formed in incomplete fusion processes which decay statistically. In particular, complex fragments appear to be produced mostly through compound nucleus decay. In the appendix a geometric-kinematic theory for incomplete fusion and the associated momentum transfer is outlined. 10 refs., 19 figs

The fusion blanket program at Chalk River

International Nuclear Information System (INIS)

Hastings, I.J.

1986-03-01

Work on the Fusion Blanket Program commenced at Chalk River in 1984 June. Co-funded by Canadian Fusion Fuels Technology Project and Atomic Energy of Canada Limited, the Program utilizes Chalk River expertise in instrumented irradiation testing, ceramics, tritium technology, materials testing and compound chemistry. This paper gives highlights of studies to date on lithium-based ceramics, leading contenders for the fusion blanket

Flunarizine Prevents Hepatitis C Virus Membrane Fusion in a Genotype-dependent Manner by Targeting the Potential Fusion Peptide within E1

Science.gov (United States)

Perin, Paula M.; Haid, Sibylle; Brown, Richard J. P.; Doerrbecker, Juliane; Schulze, Kai; Zeilinger, Carsten; von Schaewen, Markus; Heller, Brigitte; Vercauteren, Koen; Luxenburger, Eva; Baktash, Yasmine M.; Vondran, Florian W. R.; Speerstra, Sietkse; Awadh, Abdullah; Mukhtarov, Furkat; Schang, Luis M; Kirschning, Andreas; Müller, Rolf; Guzman, Carlos A.; Kaderali, Lars; Randall, Glenn; Meuleman, Philip; Ploss, Alexander; Pietschmann, Thomas

2015-01-01

To explore mechanisms of hepatitis C virus (HCV) replication we screened a compound library including licensed drugs. Flunarizine, a diphenylmethylpiperazine used to treat migraine, inhibited HCV cell entry in vitro and in vivo in a genotype-dependent fashion. Analysis of mosaic viruses between susceptible and resistant strains revealed that E1 and E2 glycoproteins confer susceptibility to flunarizine. Time of addition experiments and single particle tracking of HCV demonstrated that flunarizine specifically prevents membrane fusion. Related phenothiazines and pimozide also inhibited HCV infection and preferentially targeted HCV genotype 2 viruses. However, phenothiazines and pimozide exhibited improved genotype coverage including the difficult to treat genotype 3. Flunarizine-resistant HCV carried mutations within the alleged fusion peptide and displayed cross-resistance to these compounds, indicating that these drugs have a common mode of action. Conclusion: These observations reveal novel details about HCV membrane fusion. Moreover, flunarizine and related compounds represent first-in-class HCV fusion inhibitors that merit consideration for repurposing as cost-effective component of HCV combination therapies. PMID:26248546

Increased Total Anesthetic Time Leads to Higher Rates of Surgical Site Infections in Spinal Fusions.

Science.gov (United States)

Puffer, Ross C; Murphy, Meghan; Maloney, Patrick; Kor, Daryl; Nassr, Ahmad; Freedman, Brett; Fogelson, Jeremy; Bydon, Mohamad

2017-06-01

A retrospective review of a consecutive series of spinal fusions comparing patient and procedural characteristics of patients who developed surgical site infections (SSIs) after spinal fusion. It is known that increased surgical time (incision to closure) is associated with a higher rate of postoperative SSIs. We sought to determine whether increased total anesthetic time (intubation to extubation) is a factor in the development of SSIs as well. In spine surgery for deformity and degenerative disease, SSI has been associated with operative time, revealing a nearly 10-fold increase in SSI rates in prolonged surgery. Surgical time is associated with infections in other surgical disciplines as well. No studies have reported whether total anesthetic time (intubation to extubation) has an association with SSIs. Surgical records were searched in a retrospective fashion to identify all spine fusion procedures performed between January 2010 and July 2012. All SSIs during that timeframe were recorded and compared with the list of cases performed between 2010 and 2012 in a case-control design. There were 20 (1.7%) SSIs in this fusion cohort. On univariate analyses of operative factors, there was a significant association between total anesthetic time (Infection 7.6 ± 0.5 hrs vs. no infection -6.0 ± 0.1 hrs, P operative time (infection 5.5 ± 0.4 hrs vs. no infection - 4.4 ± 0.06 hrs, P infections, whereas level of pathology and emergent surgery were not significant. On multivariate logistic analysis, BMI and total anesthetic time remained independent predictors of SSI whereas ASA status and operative time did not. Increasing BMI and total anesthetic time were independent predictors of SSIs in this cohort of over 1000 consecutive spinal fusions. 3.

Estimating the melting point, entropy of fusion, and enthalpy of ...

Science.gov (United States)

The entropies of fusion, enthalies of fusion, and melting points of organic compounds can be estimated through three models developed using the SPARC (SPARC Performs Automated Reasoning in Chemistry) platform. The entropy of fusion is modeled through a combination of interaction terms and physical descriptors. The enthalpy of fusion is modeled as a function of the entropy of fusion, boiling point, and fexibility of the molecule. The melting point model is the enthlapy of fusion divided by the entropy of fusion. These models were developed in part to improve SPARC's vapor pressure and solubility models. These models have been tested on 904 unique compounds. The entropy model has a RMS of 12.5 J mol-1K-1. The enthalpy model has a RMS of 4.87 kJ mol-1. The melting point model has a RMS of 54.4°C. Published in the journal, SAR and QSAR in Environmental Research

On the increase of predictive performance with high-level data fusion

International Nuclear Information System (INIS)

Doeswijk, T.G.; Smilde, A.K.; Hageman, J.A.; Westerhuis, J.A.; Eeuwijk, F.A. van

2011-01-01

The combination of the different data sources for classification purposes, also called data fusion, can be done at different levels: low-level, i.e. concatenating data matrices, medium-level, i.e. concatenating data matrices after feature selection and high-level, i.e. combining model outputs. In this paper the predictive performance of high-level data fusion is investigated. Partial least squares is used on each of the data sets and dummy variables representing the classes are used as response variables. Based on the estimated responses y-hat j for data set j and class k, a Gaussian distribution p(g k |y-hat j ) is fitted. A simulation study is performed that shows the theoretical performance of high-level data fusion for two classes and two data sets. Within group correlations of the predicted responses of the two models and differences between the predictive ability of each of the separate models and the fused models are studied. Results show that the error rate is always less than or equal to the best performing subset and can theoretically approach zero. Negative within group correlations always improve the predictive performance. However, if the data sets have a joint basis, as with metabolomics data, this is not likely to happen. For equally performing individual classifiers the best results are expected for small within group correlations. Fusion of a non-predictive classifier with a classifier that exhibits discriminative ability lead to increased predictive performance if the within group correlations are strong. An example with real life data shows the applicability of the simulation results.

Intergenus Protoplast Fusion between Pichia manshurica and Rhodosporidium paludigenum to Increase the Production of Inulinase

Directory of Open Access Journals (Sweden)

Wijanarka Wijanarka

2014-12-01

Full Text Available The purposes of this study was to identify the optimum concentration of the lytic enzyme Glucanex for protoplast isolation and to conduct fusion for the purpose of increasing inulinase production. The study performs the protoplast fusion technique using Pichia manshurica and Rhodosporidium paludigenum. Protoplast fusion consists of a series of stages: protoplast isolation, protoplast fusion, protoplast regeneration, and analysis of hybrid fusion results. Protoplast isolation and fusion success rate are determined by various factors, including age of the culture, media type, and type of lytic enzymes used. Hybrid results were analyzed using a fungicide as a marker and measuring specific growth rate (μ of the hybrid compared with parental growth rates. Results demonstrated that a concentration of 4 mg/mL of Glucanex produces the greatest number of protoplasts, 7.2 x 1010 (cell/mL for P. manshurica and 8.8 x 1010 (cell/mL for Rh. paludigenum. The results of analysis of hybrid fusions indicate that the study has identified a new fusant, called fusant F4. Fusant F4 is capable of producing the highest inulinase, 0.6892 IU, compared with parentals P. manshurica, 0557 IU, and Rh. paludigenum, 0.3263 IU. Fusant F4 has specific growth rate (μ of 0.3360/h and generation time (g of 2.0629 h.

A Protein Disulfide Isomerase Gene Fusion Expression System That Increases the Extracellular Productivity of Bacillus brevis

Science.gov (United States)

Kajino, Tsutomu; Ohto, Chikara; Muramatsu, Masayoshi; Obata, Shusei; Udaka, Shigezo; Yamada, Yukio; Takahashi, Haruo

2000-01-01

We have developed a versatile Bacillus brevis expression and secretion system based on the use of fungal protein disulfide isomerase (PDI) as a gene fusion partner. Fusion with PDI increased the extracellular production of heterologous proteins (light chain of immunoglobulin G, 8-fold; geranylgeranyl pyrophosphate synthase, 12-fold). Linkage to PDI prevented the aggregation of the secreted proteins, resulting in high-level accumulation of fusion proteins in soluble and biologically active forms. We also show that the disulfide isomerase activity of PDI in a fusion protein is responsible for the suppression of the aggregation of the protein with intradisulfide, whereas aggregation of the protein without intradisulfide was prevented even when the protein was fused to a mutant PDI whose two active sites were disrupted, suggesting that another PDI function, such as chaperone-like activity, synergistically prevented the aggregation of heterologous proteins in the PDI fusion expression system. PMID:10653729

Complete fusion in light 'heavy ion' collisions

International Nuclear Information System (INIS)

Volant, C.; Wieleczko, J.P.

1979-01-01

In the last few years a large amount of data have been obtained on the complete fusion of light ions. One of the aim of these studies was to look for aspects which could not be explained by the macroscopic description of the fusion which works quite well for heavier systems. Indeed, it was suggested that for light systems the fusion could be sometimes limited by compound nucleus properties or by some particular structures in the entrance channel. In this talk new results on fusion experiments obtained by the Saclay group are presented

Towards a unified description of light ion fusion cross section excitation functions

International Nuclear Information System (INIS)

Zimmer, K.W.

1995-01-01

A description of light heavy-ion fusion, taking into account both entrance-channel characteristics and compound-nucleus properties, is derived within a unified theory of nuclear reactions. The dependence of the imaginary fusion potential on the level density of the compound nucleus is revealed. The 12 C + 12 C, 12 C + 14 N, 10 B + 16 O and 16 O + 16 O fusion cross sections are calculated for E cm ≤ 120 MeV and compared with experimental data. The excitation energy dependence of the level-density parameter of 24 Mg, 26 Al and 32 S is inferred below 5 MeV/A. A realistic nuclear level-density model, describing the experimental level-density parameters of highly excited nuclei, is shown to be consistent with both the global features and details of the fusion cross section. 12 C + 12 C and 16 O + 16 O fusion cross section oscillations are predicted at large excitation energies, reflecting the structure of the level density of the highly excited light compound nuclei. Differences of the 12 C + 14 N and 10 B + 16 O fusion reaction mechanisms are discussed in terms of specific entrance-channel characteristics. (orig.)

Towards a unified description of light ion fusion cross section excitation functions

International Nuclear Information System (INIS)

Zimmer, K.W.; Rebel, H.

1994-10-01

A description of light heavy-ion fusion, taking into account both entrace-channel characteristics and compound-nucleus properties, is derived within a unified theory of nuclear reactions. The dependence of the imaginary fusion potential on the level density of the compound nucleus is revealed. The 12 C+ 12 C, 12 C+ 14 N, 10 B+ 16 O and 16 O+ 16 O fusion cross sections are calculated for E cm ≤120 MeV and compared with experimental data. The excitation energy dependence of the level-density parameter of 24 Mg, 26 Al and 32 S is inferred below 5 MeV/A. A realistic nuclear level-density model, describing the experimental level-density parameters of highly excited nuclei, is shown to be consistent with both the global features and details of the fusion cross section. 12 C+ 12 C and 16 O+ 16 O fusion cross section oscillations are predicted at large excitation energies, reflecting the structure of the level density of the highly excited light compound nuclei. Differences of the 12 C+ 14 N and 10 B+ 16 O fusion reaction mechanisms are discussed in terms of specific entrance-channel characteristics. (orig.)

A dynamical theory of incomplete fusion reactions: The breakup-fusion reaction approach

International Nuclear Information System (INIS)

Udagawa, T.

1984-01-01

A dynamical theory of partial fusion reactions is presented, which may fill the gap between direct and compound nuclear reaction theories. With the new theory one can calculate partial fusion taking place in three-body (and many more) channels reached via direct reactions, e.g., breakup and knockout reactions. The authors present first the results for the cross section for such reactions, taking as an example breakup followed by fusion. They then discuss a physical picture which emerges from their theory, namely that the partial fusion reactions, particularly of the massive-transfer type, take place in a so-called deep peripheral region. It is also shown that the deep peripheral character of such processes diminishes as the mass of the fused system decreases, so that the reactions essentially evolve to the usual peripheral character. Finally, comparisons are made of results of numerical calculations with experimental data, taking as an example the /sup 159/Tb(/sup 14/N,α) reaction with E/sub lab/ = 95 MeV

Analyses of the activation of near term fusion reactor compound materials

International Nuclear Information System (INIS)

Lengar, I.

2007-01-01

One of the important questions that still have to be solved for the next generation fusion reactors is the choice of the material to be used for the first wall. An important criteria is low activation due to neutron bombardment from the plasma. One of the promising materials is the SiC/SiC composite. Its main elemental constituents, namely the C and Si, have very good activation characteristics. The main contribution to activity arises, however, from trace elements, which are needed in the sintering process and remain in the material afterwards. Before the preparation process of the material, the activation characteristics of individual constituents are needed. The activation properties of the whole sample could than be estimated by summing the weighted properties of individual constituents. The activity of a particular trace element is, however, not necessarily dependent only on the percentage of the element in the sample, but also on the presence of other elements in the compound due to the charge particle production and/or (n, 2n) reactions. The extension of this effect is investigated and to what extent individual calculations, performed for a single element, mimic the real situation. Further the activation characteristic for several possible sintering aid elements is theoretically investigated with the use of the FISPACT inventory code. (author)

Effect of dissipation on dynamical fusion thresholds

International Nuclear Information System (INIS)

Sierk, A.J.

1986-01-01

The existence of dynamical thresholds to fusion in heavy nuclei (A greater than or equal to 200) due to the nature of the potential-energy surface is shown. These thresholds exist even in the absence of dissipative forces, due to the coupling between the various collective deformation degrees of freedom. Using a macroscopic model of nuclear shape dynamics, It is shown how three different suggested dissipation mechanisms increase by varying amounts the excitation energy over the one-dimensional barrier required to cause compound-nucleus formation. The recently introduced surface-plus-window dissipation may give a reasonable representation of experimental data on fusion thresholds, in addition to properly describing fission-fragment kinetic energies and isoscalar giant multipole widths. Scaling of threshold results to asymmetric systems is discussed. 48 refs., 10 figs

Heavy ion fusion reactions: comparison among different models

Energy Technology Data Exchange (ETDEWEB)

Canto, L F; Carlson, B V; Hussein, M S

1988-03-01

A comparison among different ion fusion models is presented. In particular, the multistep aspects of the recently proposed Dinucleus Doorway Model are made explicit and the model is confronted with other compound nucleus limitation models. It is suggested that the latter models provide effective one-step descriptions of heavy ion fusion.

Chemical analysis developments for fusion materials studies

International Nuclear Information System (INIS)

McCown, J.J.; Baldwin, D.L.; Keough, R.F.; Van der Cook, B.P.

1985-04-01

Several projects at Hanford under the management of the Westinghouse Hanford Company have involved research and development (R and D) on fusion materials. They include work on the Fusion Materials Irradiation Test Facility and its associated Experimental Lithium System; testing of irradiated lithium compounds as breeding materials; and testing of Li and Li-Pb alloy reactions with various atmospheres, concrete, and other reactor materials for fusion safety studies. In the course of these projects, a number of interesting and challenging analytical chemistry problems were encountered. They include sampling and analysis of lithium while adding and removing elements of interest; sampling, assaying and compound identification efforts on filters, aerosol particles and fire residues; development of dissolution and analysis techniques for measuring tritium and helium in lithium ceramics including oxides, aluminates, silicates and zirconates. An overview of the analytical chemistry development problems plus equipment and procedures used will be presented

Real options valuation of fusion energy R and D programme

International Nuclear Information System (INIS)

Bednyagin, Denis; Gnansounou, Edgard

2011-01-01

This paper aims to perform a real options valuation of fusion energy R and D programme. Strategic value of thermonuclear fusion technology is estimated here based on the expected cash flows from construction and operation of fusion power plants and the real options value arising due to managerial flexibility and the underlying uncertainty. First, a basic investment option model of Black-Scholes type is being considered. Then, a fuzzy compound real R and D option model is elaborated, which reflects in a better way the multi-stage nature of the programme and takes into account the imprecision of information as one of the components of the overall programme uncertainty. Two different strategies are compared: 'Baseline' corresponding to a relatively moderate pace of fusion research, development, demonstration and deployment activities vs. 'Accelerated' strategy, which assumes a rapid demonstration and massive deployment of fusion. The conclusions are drawn from the model calculations regarding the strategic value of fusion energy R and D and the advantages of accelerated development path. - Research highlights: → Real options analysis of fusion R and D, demonstration and deployment (RDDD) programme. → ENPV of fusion RDDD programme is calculated using stochastic probabilistic simulation. → Fusion RDDD programme exhibits substantial positive real options value: Euro 245 billion. → Fuzzy compound real option valuation method provides more robust results.

Phase Transition Enthalpy Measurements of Organic and Organometallic Compounds. Sublimation, Vaporization and Fusion Enthalpies From 1880 to 2015. Part 1. C1 - C10

Science.gov (United States)

Acree, William; Chickos, James S.

2016-09-01

A compendium of phase change enthalpies published in 2010 is updated to include the period 1880-2015. Phase change enthalpies including fusion, vaporization, and sublimation enthalpies are included for organic, organometallic, and a few inorganic compounds. Part 1 of this compendium includes organic compounds from C1 to C10. Part 2 of this compendium, to be published separately, will include organic and organometallic compounds from C11 to C192. Sufficient data are presently available to permit thermodynamic cycles to be constructed as an independent means of evaluating the reliability of the data. Temperature adjustments of phase change enthalpies from the temperature of measurement to the standard reference temperature, T = 298.15 K, and a protocol for doing so are briefly discussed.

Measurements of fusion cross sections of 16O+46,50Ti systems

International Nuclear Information System (INIS)

Liguori Neto, R.

1986-01-01

Excitation functions for complete fusion of the systems 16 O + 46,50 Ti, with50)Ti, energies near and below the Coulomb barrier, were measured. With the use of the in-beam and out of beam γ spectroscopy, the formation of the compound nucleus was experimentally detected. The fusion cross was then attained by the sum of all observed compound nucleus decay channels. The limitation and advantages of measurements methods are discussed. Theoretical analysis of the experimental results using the semi-classical barrier penetration model allowed us to obtain the fusion barrier height and radius for the studied systems. These values are in good agreement with others reported for this mass range. Using the unidimensional barrier penetration model with different nuclear potentials, describing the heavy ion interactions gave theoretical fusion cross section values systematically smaller than our measured values in the energy region below the Coulomb barrier. The introduction of the nuclear surface zero point vibrations enhances the theoretical fusion cross sections in the sub-Coulomb region, but simultaneoulsy introduces an isotopic difference in the fusion excitation functions that is not observed experimentally. The statistical model predictions for the compound nucleous decay (calculated by the CASCADE program) show reasonable agreement for the more intense decay channels. (author) [pt

Proceedings of the symposium on the many facets of heavy ion fusion reactions

International Nuclear Information System (INIS)

1986-01-01

The topics of the symposium are sub- and near-barrier fusion, limitations to fusion, compound nucleus decay and spectroscopy, incomplete fusion processes, and fragmentation and liquid-gas phase transition. Separate abstracts were prepared for 54 papers in these proceedings

Cold fusion reactions with 48Ca

International Nuclear Information System (INIS)

Gaeggeler, H.W.; Jost, D.T.; Tuerler, A.

1989-04-01

Cold fusion reactions with 48 Ca on the targets 208 Pb, 209 Bi, 197 Au, 184 W, 180 Hf are reported. The experiments were performed at the velocity filter SHIP of GSI. The maximum cross sections show a steep descent by about four orders of magnitude when going from 224 Th to 228 U as compound nuclei. Between uranium and einsteinium the cross sections stay rather low and increase by about two orders of magnitude for nobelium. For lawrencium the cross section decrease again. 7 figs., 1 tab., 38 refs

Prospective Assessment of Virtual Screening Heuristics Derived Using a Novel Fusion Score.

Science.gov (United States)

Pertusi, Dante A; O'Donnell, Gregory; Homsher, Michelle F; Solly, Kelli; Patel, Amita; Stahler, Shannon L; Riley, Daniel; Finley, Michael F; Finger, Eleftheria N; Adam, Gregory C; Meng, Juncai; Bell, David J; Zuck, Paul D; Hudak, Edward M; Weber, Michael J; Nothstein, Jennifer E; Locco, Louis; Quinn, Carissa; Amoss, Adam; Squadroni, Brian; Hartnett, Michelle; Heo, Mee Ra; White, Tara; May, S Alex; Boots, Evelyn; Roberts, Kenneth; Cocchiarella, Patrick; Wolicki, Alex; Kreamer, Anthony; Kutchukian, Peter S; Wassermann, Anne Mai; Uebele, Victor N; Glick, Meir; Rusinko, Andrew; Culberson, J Christopher

2017-09-01

High-throughput screening (HTS) is a widespread method in early drug discovery for identifying promising chemical matter that modulates a target or phenotype of interest. Because HTS campaigns involve screening millions of compounds, it is often desirable to initiate screening with a subset of the full collection. Subsequently, virtual screening methods prioritize likely active compounds in the remaining collection in an iterative process. With this approach, orthogonal virtual screening methods are often applied, necessitating the prioritization of hits from different approaches. Here, we introduce a novel method of fusing these prioritizations and benchmark it prospectively on 17 screening campaigns using virtual screening methods in three descriptor spaces. We found that the fusion approach retrieves 15% to 65% more active chemical series than any single machine-learning method and that appropriately weighting contributions of similarity and machine-learning scoring techniques can increase enrichment by 1% to 19%. We also use fusion scoring to evaluate the tradeoff between screening more chemical matter initially in lieu of replicate samples to prevent false-positives and find that the former option leads to the retrieval of more active chemical series. These results represent guidelines that can increase the rate of identification of promising active compounds in future iterative screens.

Phase Transition Enthalpy Measurements of Organic and Organometallic Compounds and Ionic Liquids. Sublimation, Vaporization, and Fusion Enthalpies from 1880 to 2015. Part 2. C11-C192

Science.gov (United States)

Acree, William; Chickos, James S.

2017-03-01

The second part of this compendium concludes with a collection of phase change enthalpies of organic molecules inclusive of C11-C192 reported over the period 1880-2015. Also included are phase change enthalpies including fusion, vaporization, and sublimation enthalpies for organometallic, ionic liquids, and a few inorganic compounds. Paper I of this compendium, published separately, includes organic compounds from C1 to C10 and describes a group additivity method for evaluating solid, liquid, and gas phase heat capacities as well as temperature adjustments of phase changes. Paper II of this compendium also includes an updated version of a group additivity method for evaluating total phase change entropies which together with the fusion temperature can be useful in estimating total phase change enthalpies. Other uses include application in identifying potential substances that either form liquid or plastic crystals or exhibit additional phase changes such as undetected solid-solid transitions or behave anisotropically in the liquid state.

On the production of heavy elements by cold fusion

International Nuclear Information System (INIS)

Armbruster, P.

1985-01-01

After a short historical introduction (Section 1), this article presents new insights into the mechanism limiting the fusion of heavy nuclides (Section 2). Fusion is finally limited by the increasing Coulomb forces in the formation process of a compound system, as well as in its deexcitation. Moreover, nuclear structure effects in all stages of evaporation residue (EVR) formation are shown to be of importance. The wide field of fusion reaction studies and possible experimental techniques is projected onto the task of element synthesis, and only those aspects that are of relevance here are covered. The better understanding of EVR formation (Section 2) and the new experimental techniques (Section 3) that enabled the production of elements 107-109 (Section 4) are also discussed. In Section 5 ground-state properties and the nuclear structure of the heaviest isotopes, together with their production cross sections, are discussed. Finally, an outlook on how eventually to go beyond Z = 109 is given

Premature activation of the paramyxovirus fusion protein before target cell attachment with corruption of the viral fusion machinery.

Science.gov (United States)

Farzan, Shohreh F; Palermo, Laura M; Yokoyama, Christine C; Orefice, Gianmarco; Fornabaio, Micaela; Sarkar, Aurijit; Kellogg, Glen E; Greengard, Olga; Porotto, Matteo; Moscona, Anne

2011-11-04

Paramyxoviruses, including the childhood pathogen human parainfluenza virus type 3, enter host cells by fusion of the viral and target cell membranes. This fusion results from the concerted action of its two envelope glycoproteins, the hemagglutinin-neuraminidase (HN) and the fusion protein (F). The receptor-bound HN triggers F to undergo conformational changes that render it competent to mediate fusion of the viral and cellular membranes. We proposed that, if the fusion process could be activated prematurely before the virion reaches the target host cell, infection could be prevented. We identified a small molecule that inhibits paramyxovirus entry into target cells and prevents infection. We show here that this compound works by an interaction with HN that results in F-activation prior to receptor binding. The fusion process is thereby prematurely activated, preventing fusion of the viral membrane with target cells and precluding viral entry. This first evidence that activation of a paramyxovirus F can be specifically induced before the virus contacts its target cell suggests a new strategy with broad implications for the design of antiviral agents.

Cold fusion in symmetric 90Zr induced reactions

International Nuclear Information System (INIS)

Keller, J.G.

1985-02-01

At the velocity filter SHIP of the Society for Heavy Ion Research in Darmstadt cross sections for evaporation-residue-nucleus formation in the reactions 90 Zr+ 89 Y, sup(90,92,96)Zr, 94 Mo were measured. In four of the reactions leading to the compound nuclei 179 Au, 180 Hg, 182 Hg, and 184 Pb for the first time in reactions of two heavy partners with mass numbers >20 radiative capture, i.e. deexcitation only by emission of γ radiation, was observed. A comparison of the measured cross sections for radiative capture with evaporation calculations leads to the final conclusion that either the γ-strength in the different compound nuclei is very different, or that the energy or angular momentum dependence of the level-density is wrongly described by the Fermi gas model at energies between 5 and 20 MeV. From the cross sections for evaporation-residue-nucleus formation fusion probabilities for central collisions were derived. The fusion probabilities show a strong dependence of the sub-barrier fusion from the nuclear structure of the contributing reaction partners. The slope of the fusion probability below the classical fusion barrier cannot be consistently described even by newer models. Below the lowest fusion barrier the fusion probability decreases with decreasing energy remarkably faster that predicted by a WKB calculation. This indicates that either the shape of the barrier is different from that predicted by the potentials, or that the mass dependence of the tunnel effect is not correctly described by the WKB calculation. (orig.) [de

Vacuum pumping of tritium in fusion power reactors

International Nuclear Information System (INIS)

Coffin, D.O.; Walthers, C.R.

1979-01-01

Compound cryopumps of three different designs will be tested with deuterium-tritium (DT) mixtures under simulated fusion reactor conditions at the Tritium Systems Test Assembly (TSTA) now being constructed at the Los Alamos Scientific Laboratory (LASL). The first of these pumps is already in operation, and its preliminary performance is presented. The supporting vacuum facility necessary to regenerate these fusion facility cryopumps is also described. The next generation of fusion system vacuum pumps may include non-cryogenic or conventional-cryogenic hybrid systems, several of which are discussed

Measurements of fusion cross sections of the 16O+46,50Ti systems

International Nuclear Information System (INIS)

Liguori Neto, R.

1986-01-01

Excitation functions for complete fusion of the systems 16 O + 46,50 Ti, with energies near and below the Coulomb barrier, were measured. With the use of the in-beam and out of beam γ spectroscopy, the formation of the compound nucleus was experimentally detected. The fusion cross section was then attained by the sum of all observed compound nucleus decay channels. The limitation and advantages of measurements methods are discussed. Theoretical analysis of the experimental results using the semi-classical barrier penetration model allowed us to obtain the fusion barrier height and radius for the studied systems. These values are in good agreement with others reported for this mass range. Using the unidimensional barrier penetration model with different nuclear potentials, describing the heavy ion interactions gave theoretical fusion cross section values systematically smaller than our measured values in the energy region below the Coulomb barrier. The introduction of the nuclear surface zero point vibrations enhances the theoretical fusion cross sections in the sub-Coulomb region, but simultaneously introduces an isotopic difference in the fusion excitation functions that is not observed experimentally. The statistical model predictions for the compound nucleus decay (calculated by the CASCADE program) show reasonable agreement for the more intense decay channels [pt

Chloroquine Increases Glucose Uptake via Enhancing GLUT4 Translocation and Fusion with the Plasma Membrane in L6 Cells

Directory of Open Access Journals (Sweden)

Qi Zhou

2016-05-01

Full Text Available Background/Aims: Chloroquine can induce an increase in the cellular uptake of glucose; however, the underlying mechanism is unclear. Methods: In this study, translocation of GLUT4 and intracellular Ca2+ changes were simultaneously observed by confocal microscope in L6 cells stably over-expressing IRAP-mOrange. The GLUT4 fusion with the plasma membrane (PM was traced using HA-GLUT4-GFP. Glucose uptake was measured using a cell-based glucose uptake assay. GLUT4 protein was detected by Western blotting and mRNA level was detected by RT-PCR. Results: We found that chloroquine induced significant increases in glucose uptake, glucose transporter GLUT4 translocation to the plasma membrane (GTPM, GLUT4 fusion with the PM, and intracellular Ca2+ in L6 muscle cells. Chloroquine-induced increases of GTPM and intracellular Ca2+ were inhibited by Gallein (Gβγ inhibitor and U73122 (PLC inhibitor. However, 2-APB (IP3R blocker only blocked the increase in intracellular Ca2+ but did not inhibit GTPM increase. These results indicate that chloroquine, via the Gβγ-PLC-IP3-IP3R pathway, induces elevation of Ca2+, and this Ca2+ increase does not play a role in chloroqui-ne-evoked GTPM increase. However, GLUT4 fusion with the PM and glucose uptake were significantly inhibited with BAPTA-AM. This suggests that Ca2+ enhances GLUT4 fusion with the PM resulting in glucose uptake increase. Conclusion: Our data indicate that chloroquine via Gβγ-PLC-IP3-IP3R induces Ca2+ elevation, which in turn promotes GLUT4 fusion with the PM. Moreover, chloroquine can enhance GLUT4 trafficking to the PM. These mechanisms eventually result in glucose uptake increase in control and insulin-resistant L6 cells. These findings suggest that chloroquine might be a potential drug for improving insulin tolerance in diabetic patients.

Just-in-Time Compound Pooling Increases Primary Screening Capacity without Compromising Screening Quality.

Science.gov (United States)

Elkin, L L; Harden, D G; Saldanha, S; Ferguson, H; Cheney, D L; Pieniazek, S N; Maloney, D P; Zewinski, J; O'Connell, J; Banks, M

2015-06-01

Compound pooling, or multiplexing more than one compound per well during primary high-throughput screening (HTS), is a controversial approach with a long history of limited success. Many issues with this approach likely arise from long-term storage of library plates containing complex mixtures of compounds at high concentrations. Due to the historical difficulties with using multiplexed library plates, primary HTS often uses a one-compound-one-well approach. However, as compound collections grow, innovative strategies are required to increase the capacity of primary screening campaigns. Toward this goal, we have developed a novel compound pooling method that increases screening capacity without compromising data quality. This method circumvents issues related to the long-term storage of complex compound mixtures by using acoustic dispensing to enable "just-in-time" compound pooling directly in the assay well immediately prior to assay. Using this method, we can pool two compounds per well, effectively doubling the capacity of a primary screen. Here, we present data from pilot studies using just-in-time pooling, as well as data from a large >2-million-compound screen using this approach. These data suggest that, for many targets, this method can be used to vastly increase screening capacity without significant reduction in the ability to detect screening hits. © 2015 Society for Laboratory Automation and Screening.

Experimental study of the influence of partner structure in the fusion of the almost symmetrical systems; Etude experimentale de l`influence de la structure des partenaires dans la fusion de systemes presque symetriques

Energy Technology Data Exchange (ETDEWEB)

Stodel-Le Lay, Christelle [Lab. de Physique Corpusculaire, Caen Univ., 14 - Caen (France)

1998-12-04

The cross-sections for the formation of evaporation residues in {sup 70}Zn and {sup 86}Kr reactions with {sup 150}Nd and {sup 130,136}Xe isotopes were measured for excitation energies of the compound nuclei ({sup 216,220,222}Th) varied from 7 MeV to 70 MeV, at the linear accelerator UNILAC of the nuclear facility GSI, Darmstadt (Germany). After de-excitation by evaporation (xn,pxn and {alpha}xn), the residual nuclei are separated from the primary beam and from spurious reaction products by the velocity filter SHIP and implanted into a silicon localization detector. Their subsequent decay via alpha particles with characteristic energies allows us to identify them and to deduce their yields. Experimental fusion-evaporation excitation functions are compared with those leading to the same compound nuclei obtained with other projectile and target combinations and with those calculated with a code developed at GSI. This code allows us to evaluate the evolution of the fission probability as a function of the incident energy for each system. The variation of cross-sections and of the fusion probability is studied as a function of the macroscopic and microscopic variables of the partners. For the synthesis of super-heavy elements, these results demonstrate quantitatively the interest in using partners of fusion with closed shell structures and rich in neurons (the fusion cross-section increases by a factor of 9 for a complementary pair of neutrons). On the other hand, closed shell compound nuclei do not influence the fusion cross-section. It will be worth synthesizing isotopes approaching the predicted stability region, nuclei with Z greater than 110 using neutron rich projectiles coming from secondary beams. (author) 104 refs., 71 figs., 11 tabs.

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia.

Science.gov (United States)

Grembecka, Jolanta; He, Shihan; Shi, Aibin; Purohit, Trupta; Muntean, Andrew G; Sorenson, Roderick J; Showalter, Hollis D; Murai, Marcelo J; Belcher, Amalia M; Hartley, Thomas; Hess, Jay L; Cierpicki, Tomasz

2012-01-29

Translocations involving the mixed lineage leukemia (MLL) gene result in human acute leukemias with very poor prognosis. The leukemogenic activity of MLL fusion proteins is critically dependent on their direct interaction with menin, a product of the multiple endocrine neoplasia (MEN1) gene. Here we present what are to our knowledge the first small-molecule inhibitors of the menin-MLL fusion protein interaction that specifically bind menin with nanomolar affinities. These compounds effectively reverse MLL fusion protein-mediated leukemic transformation by downregulating the expression of target genes required for MLL fusion protein oncogenic activity. They also selectively block proliferation and induce both apoptosis and differentiation of leukemia cells harboring MLL translocations. Identification of these compounds provides a new tool for better understanding MLL-mediated leukemogenesis and represents a new approach for studying the role of menin as an oncogenic cofactor of MLL fusion proteins. Our findings also highlight a new therapeutic strategy for aggressive leukemias with MLL rearrangements.

Barrier for cold-fusion production of superheavy elements

International Nuclear Information System (INIS)

Ichikawa, Takatoshi; Iwamoto, Akira; Moeller, Peter; Sierk, Arnold J.

2005-01-01

We estimate the fusion-barrier height B fu (two-body) for approaching ions in cold-fusion reactions in a model where the projectile deformation and quadrupole zero-point vibrational energy are taken into account. This barrier height is defined as the barrier energy at the target and projectile separation distance where an original oblate deformation of projectile and/or target caused by a repulsive Coulomb force turns into a large prolate deformation caused by the attractive nuclear force as the target and projectile come closer. The instability develops before touching because the attractive short-range nuclear force overcomes the repulsive Coulomb force and the shape-stabilizing effect of shell structure. The shell structure of the doubly magic 208 Pb target is sufficiently strong that its shape remains very close to spherical in all cases studied here. The fusion potential for approaching ions in the two-body channel is calculated in the macroscopic-microscopic model with the quadrupole vibrational zero-point energy obtained in the WKB approximation. We compare our results with data from 10 experimental cold-fusion reactions and with the Bass barriers. Differences and similarities between the Yukawa-plus-exponential model and the Bass model are discussed. We also calculate five-dimensional potential-energy surfaces for the single compound system and show that well-established fission and fusion valleys are both present. For heavy systems, B fu (two-body) becomes lower than the fission barrier just beyond the ground state of the compound system. In the vicinity of this transition, the optimum collision energy for formation of evaporation residues can be expected to depend in a delicate fashion on the interplay among B fu (two-body) , the fusion valley, the fission barrier of the compound system, and the one- and two-neutron separation energies S 1n and S 2n . We discuss these issues in detail and calculate fission-barrier heights. Except for reactions in which

New approach to description of fusion-fission dynamics in super-heavy element formation

International Nuclear Information System (INIS)

Zagrebaev, V.I.

2002-01-01

A new mechanism of the fusion-fission process for a heavy nuclear system is proposed, which takes place in the (A 1 , A 2 ) space, where A 1 and A 2 are two nuclei, surrounded by a certain number of shared nucleons ΔA. The nuclei A 1 and A 2 gradually lose (or acquire) their individualities with increasing (or decreasing) a number of collectivized nucleons ΔA. The driving potential in the (A 1 , A 2 ) space is derived, which allows the calculation of both the probability of the compound nucleus formation and the mass distribution of fission and quasi-fission fragments in heavy ion fusion reactions. The cross sections of super-heavy element formation in the 'hot' and 'cold' fusion reactions have been calculated up to Z CN =118. (author)

Membrane fusion inducers, chloroquine and spermidine increase lipoplex-mediated gene transfection

International Nuclear Information System (INIS)

Wong-Baeza, Carlos; Bustos, Israel; Serna, Manuel; Tescucano, Alonso; Alcantara-Farfan, Veronica; Ibanez, Miguel; Montanez, Cecilia; Wong, Carlos; Baeza, Isabel

2010-01-01

Gene transfection into mammalian cells can be achieved with viral and non-viral vectors. Non-viral vectors, such as cationic lipids that form lipoplexes with DNA, are safer and more stable than viral vectors, but their transfection efficiencies are lower. Here we describe that the simultaneous treatment with a membrane fusion inducer (chlorpromazine or procainamide) plus the lysosomotropic agent chloroquine increases lipoplex-mediated gene transfection in human (HEK293 and C-33 A) and rat (PC12) cell lines (up to 9.2-fold), as well as in situ in BALB/c mice spleens and livers (up to 6-fold); and that the polyamine spermidine increases lipoplex-mediated gene transfection and expression in cell cultures. The use of these four drugs provides a novel, safe and relatively inexpensive way to considerably increase lipoplex-mediated gene transfection efficiency.

Post-fusion treatment with MG132 increases transcription factor expression in somatic cell nuclear transfer embryos in pigs.

Science.gov (United States)

You, Jinyoung; Lee, Joohyeong; Kim, Jinyoung; Park, Junhong; Lee, Eunsong

2010-02-01

The objective of this study was to examine the effect of post-fusion treatment of somatic cell nuclear transfer (SCNT) oocytes with the proteasomal inhibitor MG132 on maturation promoting factor (MPF) activity, nuclear remodeling, embryonic development, and gene expression of cloned pig embryos. Immediately after electrofusion, SCNT oocytes were treated with MG132 and/or caffeine for 2 hr, vanadate for 0.5 hr, or vanadate for 0.5 hr followed by MG132 for 1.5 hr. Of the MG132 concentrations tested (0-5 microM), the 1 microM concentration showed a higher rate of blastocyst formation (25.9%) than 0 (14.2%), 0.5 (16.9%), and 5 microM (16.9%). Post-fusion treatment with MG132, caffeine, and both MG132 and caffeine improved blastocyst formation (22.1%, 21.4%, and 24.4%, respectively), whereas vanadate treatment inhibited blastocyst formation (6.5%) compared to the control (11.1%). When examined 2 hr after fusion and 1 hr after activation, MPF activity remained at a higher (P fusion with caffeine and/or MG132, but it was decreased by vanadate. The rate of oocytes showing premature chromosome condensation was not altered by MG132 but was decreased by vanadate treatment. In addition, formation of single pronuclei was increased by MG132 compared to control and vanadate treatment. MG132-treated embryos showed increased expression of POU5F1, DPPA2, DPPA3, DPPA5, and NDP52l1 genes compared to control embryos. Our results demonstrate that post-fusion treatment of SCNT oocytes with MG132 prevents MPF degradation and increases expression of transcription factors in SCNT embryos, which are necessary for normal development of SCNT embryos. (c) 2009 Wiley-Liss, Inc.

Study of 9 Be + 29 Si system nuclear fusion

International Nuclear Information System (INIS)

Silva Figueira, M.C. da.

1991-01-01

Fusion cross sections for the 9 Be + 29 Si system have been measured in the energy range between 17 and 38 MeV (lab) by detecting the evaporation residues with the time of flight technique. Angular distributions have been measured from 7.5 0 C to 35 0 C in the laboratory frame at E( 9 Be) = 26 and 38 MeV. The measured fusion cross sections are significantly smaller than the total reaction cross sections obtained from fits to the elastic scattering data in the same energy range. Comparison with existing data for compound systems with A= 38 shows that this effect can not be understood in terms of the statistical yrast line of the formed compound nucleus. A systematic analysis of the energy dependence of the ratio between the fusion cross section and the total reaction cross section, for the system 9 Be + 29 Si and many other available in the literature has been performed. The saturation value can be associated to the nucleon or cluster separation energy of the light nuclei participant in the collision, leading to an hindrance of the fusion cross section. (author)

Angular momentum effects in subbarrier fusion

International Nuclear Information System (INIS)

Halbert, M.L.; Beene, J.R.; Hensley, D.C.; Honkanen, K.; Semkow, T.M.; Abenante, V.; Sarantites, D.G.; Li, Z.

1987-01-01

The authors discuss angular-momentum distributions σ l for the compound nucleus 164 Yb deduced from measurements of γ-ray multiplicity for all significant evaporation residues from fusion of 64 Ni and 100 Mo and 16 O + 148 Sm. At the lowest bombarding energies the σ l extend to higher l values than do predictions that include coupling of the principal inelastic channels, even if the coupling strengths are increased to match the experimental excitation function. Likewise, σ l from an energy-dependent real potential fitted to the excitation function fails to reproduce the experimental σ l distribution. No effects attributed to superdeformation were observed

The systematic study of the influence of neutron excess on the fusion cross-sections using different proximity-type potentials

International Nuclear Information System (INIS)

Ghodsi, O.N.; Gharaei, R.

2012-01-01

Using different types of proximity potentials, we have examined the trend of variations of barrier characteristics (barrier height and its position) as well as fusion cross-sections for 50 isotopic systems including various collisions of C, O, Mg, Si, S, Ca, Ar, Ti and Ni nuclei with the 1 ≤ N/Z < 1.6 condition for compound systems. The results of our studies reveal that the relationships between the increase of barrier positions and the decrease of barrier heights are both linear with the increase of the N/Z ratio. Moreover, fusion cross-sections also enhance linearly with the increase of this ratio. (orig.)

Decomposition of incomplete fusion

International Nuclear Information System (INIS)

Sobotka, L.B.; Sarantities, D.G.; Stracener, D.W.; Majka, Z.; Abenante, V.; Semkow, T.M.; Hensley, D.C.; Beene, J.R.; Halbert, M.L.

1989-01-01

The velocity distribution of fusion-like products formed in the reaction 701 MeV 28 Si+ 100 Mo is decomposed into 26 incomplete fusion channels. The momentum deficit of the residue per nonevaporative mass unit is approximately equal to the beam momentum per nucleon. The yields of the incomplete fusion channels correlate with the Q-value for projectile fragmentation rather than that for incomplete fusion. The backward angle multiplicities of light particles and heavy ions increase with momentum transfer, however, the heavy ion multiplicities also depend on the extent of the fragmentation of the incomplete fusion channel. These data indicate that at fixed linear momentum transfer, increased fragmentation of the unfused component is related to a reduced transferred angular momentum. 22 refs., 6 figs., 1 tab

Fusion technology 1992

International Nuclear Information System (INIS)

Ferro, C.; Gasparatto, M.; Knoepfel, H.

1993-01-01

The aim of the biennial series of symposia on the title subject, organized by the European Fusion Laboratories, is the exchange of information on the design, construction and operation of fusion experiments and on the technology being developed for the next step devices and fusion reactors. The coverage of the volume includes the technological aspects of fusion reactors in relation to new developments, this forming a guideline for the definition of future work. These proceedings comprise three volumes and contain both the invited lectures and contributed papers presented at the symposium which was attended by 569 participants from around the globe. The 343 papers, including 12 invited papers, characterize the increasing interest of industry in the fusion programme, giving a broad and current overview on the progress and trends fusion technology is experiencing now, as well as indicating the future for fusion devices

Fusion-fission dynamics and perspectives of future experiments

International Nuclear Information System (INIS)

Zagrebaev, V.I.; Itkis, M.G.; Oganessian, Yu.Ts.

2003-01-01

The paper is focused on reaction dynamics of superheavy-nucleus formation and decay at beam energies near the Coulomb barrier. The aim is to review the things we have learned from recent experiments on fusion-fission reactions leading to the formation of compound nuclei with Z ≥ 102 and from their extensive theoretical analysis. Major attention is paid to the dynamics of formation of very heavy compound nuclei taking place in strong competition with the process of fast fission (quasifission). The choice of collective degrees of freedom playing a fundamental role and finding the multidimensional driving potential and the corresponding dynamic equation regulating the whole process are discussed. A possibility of deriving the fission barriers of superheavy nuclei directly from performed experiments is of particular interest here. In conclusion, the results of a detailed theoretical analysis of available experimental data on the 'cold' and 'hot' fusion-fission reactions are presented. Perspectives of future experiments are discussed along with additional theoretical studies in this field needed for deeper understanding of the fusion-fission processes of very heavy nuclear systems

Nuclear structure effects in fusion-fission of compound systems 20,21,22Ne formed in 10,11B+10,11B reactions

International Nuclear Information System (INIS)

Singh, BirBikram; Kaur, Manpreet; Kaur, Varinderjit; Gupta, Raj K.

2014-01-01

The dynamical cluster-decay model (DCM) of Gupta and collaborators has been successfully applied to the decay of number of hot and rotating compound nuclei in different mass regions, formed in low-energy heavy ion reactions. Recently, its application to the binary symmetric decay (BSD) of very light mass compound systems 20,21,22 Ne formed in 10,11 B+ 10,11 B reactions at E lab =48 MeV is extended, as the experimental data for σ BSD Expt . is available, namely, for 20 Ne (∼ 270 mb), 21 Ne ( 22 Ne ( BSD DCM for the BSD of the three Ne systems is calculated, comprising fusion-fission σ ff and deep inelastic scattering/orbiting σorb contributions (evaluated empirically here) from compound nucleus CN and non-compound nucleus nCN processes, respectively. The significant observation from this study is that, of the total σ BSD DCM , σ ff contribution is very strong for the decay of 20 Ne (=195.270 mb; >70%), followed by 21 Ne (=65.723 mb; ∼50%) and 22 Ne (=8.677 mb; almost 10%). This means that the process of collective clusterization within the DCM is playing very strong role for the decay of 20 Ne

High Level Information Fusion (HLIF) with nested fusion loops

Science.gov (United States)

Woodley, Robert; Gosnell, Michael; Fischer, Amber

2013-05-01

Situation modeling and threat prediction require higher levels of data fusion in order to provide actionable information. Beyond the sensor data and sources the analyst has access to, the use of out-sourced and re-sourced data is becoming common. Through the years, some common frameworks have emerged for dealing with information fusion—perhaps the most ubiquitous being the JDL Data Fusion Group and their initial 4-level data fusion model. Since these initial developments, numerous models of information fusion have emerged, hoping to better capture the human-centric process of data analyses within a machine-centric framework. 21st Century Systems, Inc. has developed Fusion with Uncertainty Reasoning using Nested Assessment Characterizer Elements (FURNACE) to address challenges of high level information fusion and handle bias, ambiguity, and uncertainty (BAU) for Situation Modeling, Threat Modeling, and Threat Prediction. It combines JDL fusion levels with nested fusion loops and state-of-the-art data reasoning. Initial research has shown that FURNACE is able to reduce BAU and improve the fusion process by allowing high level information fusion (HLIF) to affect lower levels without the double counting of information or other biasing issues. The initial FURNACE project was focused on the underlying algorithms to produce a fusion system able to handle BAU and repurposed data in a cohesive manner. FURNACE supports analyst's efforts to develop situation models, threat models, and threat predictions to increase situational awareness of the battlespace. FURNACE will not only revolutionize the military intelligence realm, but also benefit the larger homeland defense, law enforcement, and business intelligence markets.

Rho GTPase activity modulates paramyxovirus fusion protein-mediated cell-cell fusion

International Nuclear Information System (INIS)

Schowalter, Rachel M.; Wurth, Mark A.; Aguilar, Hector C.; Lee, Benhur; Moncman, Carole L.; McCann, Richard O.; Dutch, Rebecca Ellis

2006-01-01

The paramyxovirus fusion protein (F) promotes fusion of the viral envelope with the plasma membrane of target cells as well as cell-cell fusion. The plasma membrane is closely associated with the actin cytoskeleton, but the role of actin dynamics in paramyxovirus F-mediated membrane fusion is unclear. We examined cell-cell fusion promoted by two different paramyxovirus F proteins in three cell types in the presence of constitutively active Rho family GTPases, major cellular coordinators of actin dynamics. Reporter gene and syncytia assays demonstrated that expression of either Rac1 V12 or Cdc42 V12 could increase cell-cell fusion promoted by the Hendra or SV5 glycoproteins, though the effect was dependent on the cell type expressing the viral glycoproteins. In contrast, RhoA L63 decreased cell-cell fusion promoted by Hendra glycoproteins but had little affect on SV5 F-mediated fusion. Also, data suggested that GTPase activation in the viral glycoprotein-containing cell was primarily responsible for changes in fusion. Additionally, we found that activated Cdc42 promoted nuclear rearrangement in syncytia

Ocean acidification increases the accumulation of toxic phenolic compounds across trophic levels

KAUST Repository

Jin, Peng; Wang, Tifeng; Liu, Nana; Dupont, Sam; Beardall, John; Boyd, Philip W.; Riebesell, Ulf; Gao, Kunshan

2015-01-01

Increasing atmospheric CO2 concentrations are causing ocean acidification (OA), altering carbonate chemistry with consequences for marine organisms. Here we show that OA increases by 46–212% the production of phenolic compounds in phytoplankton grown under the elevated CO2 concentrations projected for the end of this century, compared with the ambient CO2 level. At the same time, mitochondrial respiration rate is enhanced under elevated CO2 concentrations by 130–160% in a single species or mixed phytoplankton assemblage. When fed with phytoplankton cells grown under OA, zooplankton assemblages have significantly higher phenolic compound content, by about 28–48%. The functional consequences of the increased accumulation of toxic phenolic compounds in primary and secondary producers have the potential to have profound consequences for marine ecosystem and seafood quality, with the possibility that fishery industries could be influenced as a result of progressive ocean changes.

Ocean acidification increases the accumulation of toxic phenolic compounds across trophic levels

KAUST Repository

Jin, Peng

2015-10-27

Increasing atmospheric CO2 concentrations are causing ocean acidification (OA), altering carbonate chemistry with consequences for marine organisms. Here we show that OA increases by 46–212% the production of phenolic compounds in phytoplankton grown under the elevated CO2 concentrations projected for the end of this century, compared with the ambient CO2 level. At the same time, mitochondrial respiration rate is enhanced under elevated CO2 concentrations by 130–160% in a single species or mixed phytoplankton assemblage. When fed with phytoplankton cells grown under OA, zooplankton assemblages have significantly higher phenolic compound content, by about 28–48%. The functional consequences of the increased accumulation of toxic phenolic compounds in primary and secondary producers have the potential to have profound consequences for marine ecosystem and seafood quality, with the possibility that fishery industries could be influenced as a result of progressive ocean changes.

Probe transfer with and without membrane fusion in a fluorescence fusion assay

NARCIS (Netherlands)

Ohki, S; Flanagan, TD; Hoekstra, D

1998-01-01

An analysis of the R(18) fusion assay was made during the fusion of the Sendai virus with erythrocyte ghosts. The increase in R(18) fluorescence, reflecting the interaction process, was evaluated in terms of the different processes that in principle may contribute to this increase, that is,

Optimization of nonthermal fusion power consistent with channeling of charged fusion product energy

International Nuclear Information System (INIS)

Snyder, P.B.; Herrmann, M.C.; Fisch, N.J.

1994-01-01

If the energy of charged fusion products can be diverted directly to fuel ions, non-Maxwellian fuel ion distributions and temperature differences between species will result. To determine the importance of these nonthermal effects, the fusion power density is optimized at constant-β for non-thermal distributions that are self-consistently maintained by channeling of energy from charged fusion products. For D-T and D- 3 He reactors, with 75% of charged fusion product power diverted to fuel ions, temperature differences between electrons and ions increase the reactivity by 40-70%, while non-Maxwellian fuel ion distributions and temperature differences between ionic species increase the reactivity by an additional 3-15%

Fusion Power Deployment

International Nuclear Information System (INIS)

Schmidt, J.A.; Ogden, J.M.

2002-01-01

Fusion power plants could be part of a future portfolio of non-carbon dioxide producing energy supplies such as wind, solar, biomass, advanced fission power, and fossil energy with carbon dioxide sequestration. In this paper, we discuss key issues that could impact fusion energy deployment during the last half of this century. These include geographic issues such as resource availability, scale issues, energy storage requirements, and waste issues. The resource needs and waste production associated with fusion deployment in the U.S. should not pose serious problems. One important feature of fusion power is the fact that a fusion power plant should be locatable within most local or regional electrical distribution systems. For this reason, fusion power plants should not increase the burden of long distance power transmission to our distribution system. In contrast to fusion power, regional factors could play an important role in the deployment of renewable resources such as wind, solar and biomass or fossil energy with CO2 sequestration. We examine the role of these regional factors and their implications for fusion power deployment

Fusion facility siting considerations

International Nuclear Information System (INIS)

Bussell, G.T.

1985-01-01

Inherent in the fusion program's transition from hydrogen devices to commercial power machines is a general increase in the size and scope of succeeding projects. This growth will lead to increased emphasis on safety, environmental impact, and the external effects of fusion in general, and of each new device in particular. A critically important consideration in this regard is site selection. The purpose of this paper is to examine major siting issues that may affect the economics, safety, and environmental impact of fusion

Fusion dynamics in 40Ca induced reactions

International Nuclear Information System (INIS)

Prasad, E.; Hinde, D.J.; Williams, E.

2017-01-01

Synthesis of superheavy elements (SHEs) and investigation of their properties are among the most challenging research topics in modern science. A non-compound nuclear process called quasi fission is partly responsible for the very low production cross sections of SHEs. The formation and survival probabilities of the compound nucleus (CN) strongly depend on the competition between fusion and quasi fission. A clear understanding of these processes and their dynamics is required to make reliable predictions of the best reactions to synthesise new SHEs. All elements beyond Nh are produced using hot fusion reactions and beams of 48 Ca were used in most of these experiments. In this context a series of fission measurements have been carried out at the Australian National University (ANU) using 40;48 Ca beams on various targets ranging from 142 Nd to 249 Cf. Some of the 40 Ca reactions will be discussed in this symposium

Development of 'low activation superconducting wire' for an advanced fusion reactor

International Nuclear Information System (INIS)

Hishinuma, Y.; Yamada, S.; Sagara, A.; Kikuchi, A.; Takeuchi, T.; Matsuda, K.; Taniguchi, H.

2011-01-01

In the D-T burning plasma reactor beyond ITER such as DEMO and fusion power plants assuming the steady-state and long time operation, it will be necessary to consider carefully induced radioactivity and neutron irradiation properties on the all components for fusion reactors. The decay time of the induced radioactivity can control the schedule and scenarios of the maintenance and shutdown on the fusion reactor. V 3 Ga and MgB 2 compound have shorter decay time within 1 years and they will be desirable as a candidate material to realize 'low activation and high magnetic field superconducting magnet' for advanced fusion reactor. However, it is well known that J c -B properties of V 3 Ga and MgB 2 wires are lower than that of the Nb-based A15 compound wires, so the J c -B enhancements on the V 3 Ga and MgB 2 wires are required in order to apply for an advanced fusion reactor. We approached and succeeded to developing the new process in order to improve J c properties of V 3 Ga and MgB 2 wires. In this paper, the recent activities for the J c improvements and detailed new process in V 3 Ga and MgB 2 wires are investigated. (author)

Fusion Canada issue 17

International Nuclear Information System (INIS)

1992-05-01

A short bulletin from the National Fusion Program. Included in this issue is a report on increased funding for the Canadian Fusion Program, news of the compact Toroid fuelling gun, an update on Tokamak de Varennes, the Canada - U.S. fusion meeting, measurements of plasma flow velocity, and replaceable Tokamak divertors. 4 figs

Fusion Canada issue 17

Energy Technology Data Exchange (ETDEWEB)

NONE

1992-05-01

A short bulletin from the National Fusion Program. Included in this issue is a report on increased funding for the Canadian Fusion Program, news of the compact Toroid fuelling gun, an update on Tokamak de Varennes, the Canada - U.S. fusion meeting, measurements of plasma flow velocity, and replaceable Tokamak divertors. 4 figs.

Effects of successive critical distances in heavy ion fusion reactions

International Nuclear Information System (INIS)

Lee, S.M.; Nakagawa, T.; Matsuse, T.

1984-01-01

The concept of Successive Critical Distances is presented. It appears that whether the fusion cross section is limited by compound nucleus or entrance channel properties depends on the degree of asymmetry of the fusing nuclei. Only in the near to symmetry case does the Statistical Yrast Line emerge as a limiting factor. Otherwise, the critical angular momentum for fusion is restricted by a critical distance

Pre-compound emission in low-energy heavy-ion interactions

Directory of Open Access Journals (Sweden)

Kumar Sharma Manoj

2017-01-01

Full Text Available Recent experimental studies have shown the presence of pre-compound emission component in heavy ion reactions at low projectile energy ranging from 4 to 7 MeV/nucleons. In earlier measurements strength of the pre-compound component has been estimated from the difference in forward-backward distributions of emitted particles. Present measurement is a part of an ongoing program on the study of reaction dynamics of heavy ion interactions at low energies aimed at investigating the effect of momentum transfer in compound, precompound, complete and incomplete fusion processes in heavy ion reactions. In the present work on the basis of momentum transfer the measurement of the recoil range distributions of heavy residues has been used to decipher the components of compound and pre-compound emission processes in the fusion of 16O projectile with 159Tb and 169Tm targets. The analysis of recoil range distribution measurements show two distinct linear momentum transfer components corresponding to pre-compound and compound nucleus processes are involved. In order to obtain the mean input angular momentum associated with compound and pre-compound emission processes, an online measurement of the spin distributions of the residues has been performed. The analysis of spin distribution indicate that the mean input angular momentum associated with pre-compound products is found to be relatively lower than that associated with compound nucleus process. The pre-compound components obtained from the present analysis are consistent with those obtained from the analysis of excitation functions.

Pre-compound emission in low-energy heavy-ion interactions

Science.gov (United States)

Sharma, Manoj Kumar; Shuaib, Mohd.; Sharma, Vijay R.; Yadav, Abhishek; Singh, Pushpendra P.; Singh, Devendra P.; Unnati; Singh, B. P.; Prasad, R.

2017-11-01

Recent experimental studies have shown the presence of pre-compound emission component in heavy ion reactions at low projectile energy ranging from 4 to 7 MeV/nucleons. In earlier measurements strength of the pre-compound component has been estimated from the difference in forward-backward distributions of emitted particles. Present measurement is a part of an ongoing program on the study of reaction dynamics of heavy ion interactions at low energies aimed at investigating the effect of momentum transfer in compound, precompound, complete and incomplete fusion processes in heavy ion reactions. In the present work on the basis of momentum transfer the measurement of the recoil range distributions of heavy residues has been used to decipher the components of compound and pre-compound emission processes in the fusion of 16O projectile with 159Tb and 169Tm targets. The analysis of recoil range distribution measurements show two distinct linear momentum transfer components corresponding to pre-compound and compound nucleus processes are involved. In order to obtain the mean input angular momentum associated with compound and pre-compound emission processes, an online measurement of the spin distributions of the residues has been performed. The analysis of spin distribution indicate that the mean input angular momentum associated with pre-compound products is found to be relatively lower than that associated with compound nucleus process. The pre-compound components obtained from the present analysis are consistent with those obtained from the analysis of excitation functions.

Characterization of the fusion-fission process in light nuclear systems

International Nuclear Information System (INIS)

Anjos, R.M. dos.

1992-01-01

Fusion cross sections measurements of highly damped processes and elastic scattering were performed for the 16, 17, 18 O + 10, 11 B and 19 F + 9 Be, in the incident energy interval 22 ≤ E LAB ≤ 64 MeV. Evidences are presented that highly damped binary processes observed in these systems are originated from a fusion-fission process rather than a dinuclear ''orbiting'' mechanism. The relative importance of the fusion-fission process in these very light systems is demonstrated both by the experimental results, which indicate a statistically balanced compound nucleus fission process occurrence, and theoretical calculations. (L.C.J.A.)

Cold fusion

International Nuclear Information System (INIS)

Suh, Suk Yong; Sung, Ki Woong; Kang, Joo Sang; Lee, Jong Jik

1995-02-01

So called 'cold fusion phenomena' are not confirmed yet. Excess heat generation is very delicate one. Neutron generation is most reliable results, however, the records are erratic and the same results could not be repeated. So there is no reason to exclude the malfunction of testing instruments. The same arguments arise in recording 4 He, 3 He, 3 H, which are not rich in quantity basically. An experiment where plenty of 4 He were recorded is attached in appendix. The problem is that we are trying to search cold fusion which is permitted by nature or not. The famous tunneling effect in quantum mechanics will answer it, however, the most fusion rate is known to be negligible. The focus of this project is on the theme that how to increase that negligible fusion rate. 6 figs, 4 tabs, 1512 refs. (Author)

Fusion rings and fusion ideals

DEFF Research Database (Denmark)

Andersen, Troels Bak

by the so-called fusion ideals. The fusion rings of Wess-Zumino-Witten models have been widely studied and are well understood in terms of precise combinatorial descriptions and explicit generating sets of the fusion ideals. They also appear in another, more general, setting via tilting modules for quantum......This dissertation investigates fusion rings, which are Grothendieck groups of rigid, monoidal, semisimple, abelian categories. Special interest is in rational fusion rings, i.e., fusion rings which admit a finite basis, for as commutative rings they may be presented as quotients of polynomial rings...

Constraining statistical-model parameters using fusion and spallation reactions

Directory of Open Access Journals (Sweden)

Charity Robert J.

2011-10-01

Full Text Available The de-excitation of compound nuclei has been successfully described for several decades by means of statistical models. However, such models involve a large number of free parameters and ingredients that are often underconstrained by experimental data. We show how the degeneracy of the model ingredients can be partially lifted by studying different entrance channels for de-excitation, which populate different regions of the parameter space of the compound nucleus. Fusion reactions, in particular, play an important role in this strategy because they fix three out of four of the compound-nucleus parameters (mass, charge and total excitation energy. The present work focuses on fission and intermediate-mass-fragment emission cross sections. We prove how equivalent parameter sets for fusion-fission reactions can be resolved using another entrance channel, namely spallation reactions. Intermediate-mass-fragment emission can be constrained in a similar way. An interpretation of the best-fit IMF barriers in terms of the Wigner energies of the nascent fragments is discussed.

Cold fusion

Energy Technology Data Exchange (ETDEWEB)

Suh, Suk Yong; Sung, Ki Woong; Kang, Joo Sang; Lee, Jong Jik [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1995-02-01

So called `cold fusion phenomena` are not confirmed yet. Excess heat generation is very delicate one. Neutron generation is most reliable results, however, the records are erratic and the same results could not be repeated. So there is no reason to exclude the malfunction of testing instruments. The same arguments arise in recording {sup 4}He, {sup 3}He, {sup 3}H, which are not rich in quantity basically. An experiment where plenty of {sup 4}He were recorded is attached in appendix. The problem is that we are trying to search cold fusion which is permitted by nature or not. The famous tunneling effect in quantum mechanics will answer it, however, the most fusion rate is known to be negligible. The focus of this project is on the theme that how to increase that negligible fusion rate. 6 figs, 4 tabs, 1512 refs. (Author).

Magnetic fusion reactor economics

International Nuclear Information System (INIS)

Krakowski, R.A.

1995-01-01

An almost primordial trend in the conversion and use of energy is an increased complexity and cost of conversion systems designed to utilize cheaper and more-abundant fuels; this trend is exemplified by the progression fossil fission → fusion. The present projections of the latter indicate that capital costs of the fusion ''burner'' far exceed any commensurate savings associated with the cheapest and most-abundant of fuels. These projections suggest competitive fusion power only if internal costs associate with the use of fossil or fission fuels emerge to make them either uneconomic, unacceptable, or both with respect to expensive fusion systems. This ''implementation-by-default'' plan for fusion is re-examined by identifying in general terms fusion power-plant embodiments that might compete favorably under conditions where internal costs (both economic and environmental) of fossil and/or fission are not as great as is needed to justify the contemporary vision for fusion power. Competitive fusion power in this context will require a significant broadening of an overly focused program to explore the physics and simbiotic technologies leading to more compact, simplified, and efficient plasma-confinement configurations that reside at the heart of an attractive fusion power plant

On fusion/fission chain reactions in the Fleischmann-Pons cold fusion experiment

International Nuclear Information System (INIS)

Anghaie, S.; Froelich, P.; Monkhorst, H.J.

1990-01-01

In this paper the possibility of fusion/fission chain reactions following d-d source reactions in electrochemical cold fusion experiments have been investigated. The recycling factors for the charged particles in fusion reactions with consumable nuclei deuteron, 6 Li nd 7 Li, are estimated. It is concluded that, based on the established nuclear fusion cross sections and electronic stopping power, the recycling factor is four to five orders of magnitude less than required for close to critical conditions. It is argued that the cross generation of charged particles by neutrons does not play a significant role in this process, even if increased densities at the surface of electrodes do occur

An introduction to hybrid fusion

International Nuclear Information System (INIS)

Reynolds, J.A.

1982-01-01

This report gives a brief introduction to some hybrid fusion proposals. The idea is to take advantage of the high neutron energy in fusion compared to fission either to breed fuel more efficiently than in a fast reactor, or increase the power output by fission of U 238 or transmute radioactive waste. The penalty is an increased cost and complexity of the blanket and the loss of environmental and safety arguments for fusion systems which rest on their low inventory of radioactive materials. (author)

Prospects for alternative Fusion Fuels

International Nuclear Information System (INIS)

Glancy, J.

1986-01-01

The author has worked on three different magnetic confinement concepts for alternate fusion fueled reactors: tokamaks; tanden mirrors, and reversed field pinches. The focus of this article is on prospects for alternate fusion fuels as the author sees them relative to the other choices: increased numbers of coal plants, fission reactors, renewables, and D-T fusion. Discussion is limited on the consideration of alternate fusion fuels to the catalyzed deuterium-deuterium fuel cycle. Reasons for seeking an alternate energy source are cost, a more secure fuel supply, environmental impact and safety. The technical risks associated with development of fusion are examined briefly

Synthesis of superheavy elements and dinuclear-system concept of compound-nucleus formation

Energy Technology Data Exchange (ETDEWEB)

Antonenko, N.V.; Adamian, G.G.; Cherepanov, E.A. [Joint Institute for Nuclear Research, Dubna (Russian Federation)] [and others

1996-12-31

Dinuclear system concept is applied to the analysis of reactions used for the synthesis of elements with Z = 110, 112, 114, and 116. The inner fusion barriers obtained for these reactions are in good agreement with the experimental estimations resulted from the excitation energies of compound nuclei. A model is suggested for the calculation of the competition between complete fusion and quasifission in reactions with heavy nuclei. The fusion rate through the inner fusion barrier in mass asymmetry is found by using the multidimensional Kramers-type stationary solution of the Fokker-Planck equation. The influence of dissipative effects on the dynamics of nuclear fusion is considered.

Measles Virus Fusion Protein: Structure, Function and Inhibition

Directory of Open Access Journals (Sweden)

Philippe Plattet

2016-04-01

Full Text Available Measles virus (MeV, a highly contagious member of the Paramyxoviridae family, causes measles in humans. The Paramyxoviridae family of negative single-stranded enveloped viruses includes several important human and animal pathogens, with MeV causing approximately 120,000 deaths annually. MeV and canine distemper virus (CDV-mediated diseases can be prevented by vaccination. However, sub-optimal vaccine delivery continues to foster MeV outbreaks. Post-exposure prophylaxis with antivirals has been proposed as a novel strategy to complement vaccination programs by filling herd immunity gaps. Recent research has shown that membrane fusion induced by the morbillivirus glycoproteins is the first critical step for viral entry and infection, and determines cell pathology and disease outcome. Our molecular understanding of morbillivirus-associated membrane fusion has greatly progressed towards the feasibility to control this process by treating the fusion glycoprotein with inhibitory molecules. Current approaches to develop anti-membrane fusion drugs and our knowledge on drug resistance mechanisms strongly suggest that combined therapies will be a prerequisite. Thus, discovery of additional anti-fusion and/or anti-attachment protein small-molecule compounds may eventually translate into realistic therapeutic options.

Heavy-ion optical potential for sub-barrier fusion deduced from a dispersion relation

International Nuclear Information System (INIS)

Kim, B.T.; Kim, H.C.; Park, K.E.

1988-01-01

The heavy-ion energy-dependent optical potentials for the 16 O+ 208 Pb system are deduced from a dispersion relation. These potentials are used to analyze the elastic scattering, fusion, and spin distributions of compound nuclei for the system in a unified way based on the direct reaction theory. It turns out that the energy dependence of the optical potential is essential in explaining the data at near- and sub-barrier energies. The real part of the energy-dependent optical potential deduced was also used in calculating the elastic and fusion cross sections by the conventional barrier penetration model using an incoming wave boundary condition. The predictions of the elastic scattering, fusion cross sections, and the spin distributions of compound nuclei are not satisfactory compared with those from the direct reaction approach. It seems to originate from the fact that this model neglects absorption around the Coulomb barrier region

Reaction mechanisms in heavy ion fusion

Directory of Open Access Journals (Sweden)

Lubian J.

2011-10-01

Full Text Available We discuss the reaction mechanisms involved in heavy ion fusion. We begin with collisions of tightly bound systems, considering three energy regimes: energies above the Coulomb barrier, energies just below the barrier and deep sub-barrier energies. We show that channel coupling effects may influence the fusion process at above-barrier energies, increasing or reducing the cross section predicted by single barrier penetration model. Below the Coulomb barrier, it enhances the cross section, and this effect increases with the system’s size. It is argued that this behavior can be traced back to the increasing importance of Coulomb coupling with the charge of the collision partners. The sharp drop of the fusion cross section observed at deep sub-barrier energies is addressed and the theoretical approaches to this phenomenon are discussed. We then consider the reaction mechanisms involved in fusion reactions of weakly bound systems, paying particular attention to the calculations of complete and incomplete fusion available in the literature.

Comparison of cross sections for C+O reactions in the second regime of complete fusion

International Nuclear Information System (INIS)

Beck, C.; Haas, F.; Freeman, R.M.; Heusch, B.; Coffin, J.P.; Guillaume, G.; Rami, F.; Wagner, P.

1985-01-01

Kinetic energy spectra, angular distributions, and elemental yield distributions have been measured for the 12 C + 16 O, 12 C + 18 O and 13 C + 17 O reaction products over an energy range from 2 to 7 times the Coulomb barrier energy. A careful kinematic analysis of the evaporation residues and comparisons with statistical model calculations show that fusion proceeds with full momentum transfer followed by a statistical decay of the compound nucleus. The competition between complete fusion process and peripheral reactions in the 12 C + 16 O system is less important than for the 12 C + 18 O and 13 C + 17 O reactions. The unexpectedly high 12 C + 16 O complete fusion cross sections are related to the possible occurence of a superdeformation of the 28 Si compound nucleus

Status of fusion technology

International Nuclear Information System (INIS)

Mohan, Ashok

1978-01-01

The current status of fusion technology is surveyed. Limited reserves of fossil fuel and dangers of proliferation from nuclear reactors have brought into focus the need to develop an optional energy source. Fusion is being looked upon as an optional energy source which is free from environmental hazards unlike fossil fuels and nuclear reactors. Investments in R and D of fusion energy have increased rapidly in USA, Japan, USSR and European countries. Out of the various fusion fuels known, a mixture of D and T is widely chosen. The main problem in fusion technology is the confinement of plasma for a time sufficient to start the fusion reaction. This can be done magnetically or inertially. The three approaches to magnetic confinement are : (1) tokamak, (2) mirror and (3) pinch. Inertial confinement makes use of lasers or electron beams or ion beams. Both the methods of confinement i.e. magnetic and inertial have problems which are identified and their nature is discussed. (M.G.B.)

Fusion spectroscopy

International Nuclear Information System (INIS)

Peacock, N.J.

1995-09-01

This article traces developments in the spectroscopy of high temperature laboratory plasma used in controlled fusion research from the early 1960's until the present. These three and a half decades have witnessed many orders of magnitude increase in accessible plasma parameters such as density and temperature as well as particle and energy confinement timescales. Driven by the need to interpret the radiation in terms of the local plasma parameters, the thrust of fusion spectroscopy has been to develop our understanding of (i) the atomic structure of highly ionised atoms, usually of impurities in the hydrogen isotope fuel; (ii) the atomic collision rates and their incorporation into ionization structure and emissivity models that take into account plasma phenomena like plasma-wall interactions, particle transport and radiation patterns; (iii) the diagnostic applications of spectroscopy aided by increasingly sophisticated characterisation of the electron fluid. These topics are discussed in relation to toroidal magnetically confined plasmas, particularly the Tokamak which appears to be the most promising approach to controlled fusion to date. (author)

Fusion Canada issue 29

International Nuclear Information System (INIS)

1995-10-01

A short bulletin from the National Fusion Program highlighting in this issue Canada-Europe Accords: 5 year R and D collaboration for the International Thermonuclear Experimental Reactor (ITER) AECL is designated to arrange and implement the Memorandum of Understanding (MOU) and the ITER Engineering Design Activities (EDA) while EUROTAM is responsible for operating Europe's Fusion R and D programs plus MOU and EDA. The MOU includes tokamaks, plasma physics, fusion technology, fusion fuels and other approaches to fusion energy (as alternatives to tokamaks). STOR-M Tokamak was restarted at the University of Saskatchewan following upgrades to the plasma chamber to accommodate the Compact Toroid (CT) injector. The CT injector has a flexible attachment thus allowing for injection angle adjustments. Real-time video images of a single plasma discharge on TdeV showing that as the plasma density increases, in a linear ramp divertor, the plasma contact with the horizontal plate decreases while contact increases with the oblique plate. Damage-resistant diffractive optical elements (DOE) have been developed for Inertial Confinement Fusion (ICF) research by Gentac Inc. and the National Optics Institute, laser beam homogeniser and laser harmonic separator DOE can also be made using the same technology. Studies using TdeV indicate that a divertor will be able to pump helium from the tokamak with a detached-plasma divertor but helium extraction performance must first be improved, presently the deuterium:helium retention radio-indicates that in order to pump enough helium through a fusion reactor, too much deuterium-tritium fuel would be pumped out. 2 fig

Kinetic advantage of controlled intermediate nuclear fusion

International Nuclear Information System (INIS)

Guo Xiaoming

2012-01-01

The dominated process of controlled fusion is to let nuclei gain enough kinetic energy to overcome Coulomb barrier. As a result, a fusion scheme can consider two factors in its design: to increase kinetic energy of nuclei and to alter the Coulomb barrier. Cold Fusion and Hot fusion are all one-factor schemes while Intermediate Fusion is a twofactors scheme. This made CINF kinetically superior. Cold Fusion reduces deuteron-deuteron distance, addressing Coulomb barrier, and Hot Fusion heat up plasma into extreme high temperature, addressing kinetic energy. Without enough kinetic energy made Cold Fusion skeptical. Extreme high temperature made Hot Fusion very difficult to engineer. Because CIFN addresses both factors, CIFN is a more promising technique to be industrialized.

Neutron emission as a probe of fusion-fission and quasi-fission dynamics

International Nuclear Information System (INIS)

Hinde, D.J.

1991-01-01

Pre- and post scission neutron yeilds have been measured as a function of projectile mass, compound nucleus fissility, and fission mass-split and total kinetic energy (TKE) for 27 fusion-fission and quasi-fission reactions induced by beams of 16,18 O, 40 Ar and 64 Ni. A new method of interpretation of experimental pre-scission neutron multiplicities ν-pre and mean kinetic energies ε ν allows the extraction of fission time scales with much less uncertainty than previously, all fusion-fission results being consistent with a dynamical time scale of (35±15) x 10 -21 s for symmetric fission. All reactions show that ν-pre falls quite rapidly with increasing mass-asymmetry; evidence is presented that for fusion-fission reactions this is partly due to a reduction of the dynamical fission time scale with mass-asymmetry. For quasi-fission, the data indicate that the pre-scission multiplicity and mean neutron kinetic energy are very sensitive to the final mass-asymmetry, but that the time scale is virtually independent of mass-asymmetry. It is concluded that for fusion-fission there is no dependence of ν-pre on TKE, whilst for 64 Ni-induced quasi-fission reactions, a strong increase of ν-pre with decreasing TKE is observed, probably largely caused by neutron emission during the acceleration time of the fission fragments in these fast reactions. Interpretation of post-scission multiplicities in terms of fragment excitation energies leads to deduced time scales consistent with those determined from the pre-scission data. 54 refs., 17 tabs., 25 figs

InFusion: Advancing Discovery of Fusion Genes and Chimeric Transcripts from Deep RNA-Sequencing Data.

Directory of Open Access Journals (Sweden)

Konstantin Okonechnikov

Full Text Available Analysis of fusion transcripts has become increasingly important due to their link with cancer development. Since high-throughput sequencing approaches survey fusion events exhaustively, several computational methods for the detection of gene fusions from RNA-seq data have been developed. This kind of analysis, however, is complicated by native trans-splicing events, the splicing-induced complexity of the transcriptome and biases and artefacts introduced in experiments and data analysis. There are a number of tools available for the detection of fusions from RNA-seq data; however, certain differences in specificity and sensitivity between commonly used approaches have been found. The ability to detect gene fusions of different types, including isoform fusions and fusions involving non-coding regions, has not been thoroughly studied yet. Here, we propose a novel computational toolkit called InFusion for fusion gene detection from RNA-seq data. InFusion introduces several unique features, such as discovery of fusions involving intergenic regions, and detection of anti-sense transcription in chimeric RNAs based on strand-specificity. Our approach demonstrates superior detection accuracy on simulated data and several public RNA-seq datasets. This improved performance was also evident when evaluating data from RNA deep-sequencing of two well-established prostate cancer cell lines. InFusion identified 26 novel fusion events that were validated in vitro, including alternatively spliced gene fusion isoforms and chimeric transcripts that include intergenic regions. The toolkit is freely available to download from http:/bitbucket.org/kokonech/infusion.

Optical Fiber Fusion Splicing

CERN Document Server

Yablon, Andrew D

2005-01-01

This book is an up-to-date treatment of optical fiber fusion splicing incorporating all the recent innovations in the field. It provides a toolbox of general strategies and specific techniques that the reader can apply when optimizing fusion splices between novel fibers. It specifically addresses considerations important for fusion splicing of contemporary specialty fibers including dispersion compensating fiber, erbium-doped gain fiber, polarization maintaining fiber, and microstructured fiber. Finally, it discusses the future of optical fiber fusion splicing including silica and non-silica based optical fibers as well as the trend toward increasing automation. Whilst serving as a self-contained reference work, abundant citations from the technical literature will enable readers to readily locate primary sources.

Canadian fusion fuels technology project

International Nuclear Information System (INIS)

1986-01-01

The Canadian Fusion Fuels Technology Project was launched in 1982 to coordinate Canada's provision of fusion fuels technology to international fusion power development programs. The project has a mandate to extend and adapt existing Canadian tritium technologies for use in international fusion power development programs. 1985-86 represents the fourth year of the first five-year term of the Canadian Fusion Fuels Technology Project (CFFTP). This reporting period coincides with an increasing trend in global fusion R and D to direct more effort towards the management of tritium. This has resulted in an increased linking of CFFTP activities and objectives with those of facilities abroad. In this way there has been a continuing achievement resulting from CFFTP efforts to have cooperative R and D and service activities with organizations abroad. All of this is aided by the cooperative international atmosphere within the fusion community. This report summarizes our past year and provides some highlights of the upcoming year 1986/87, which is the final year of the first five-year phase of the program. AECL (representing the Federal Government), the Ministry of Energy (representing Ontario) and Ontario Hydro, have given formal indication of their intent to continue with a second five-year program. Plans for the second phase will continue to emphasize tritium technology and remote handling

Search for entrance channel effects in fusion reactions via neutron evaporation

International Nuclear Information System (INIS)

Ajay Kumar; Kaur, J.; Kumar, A.; Singh, G.; Govil, I.M.; Rakesh Kumar; Datta, S.K.; Chatterjee, M.B.; Yogi, B.K.

2001-01-01

It is generally expected that the compound nuclei formed at the given excitation energies and the angular momenta follow a statistical decay pattern independent of a particular reaction that led to fusion. In order to search the entrance channel effects in the decay of compound nucleus, the reaction 16 O + 64 Zn at oxygen beam energy of 91 MeV and 95 MeV are investigated

Nuclear hydrogen production: re-examining the fusion option

International Nuclear Information System (INIS)

Baindur, S.

2007-01-01

This paper describes a scheme for nuclear hydrogen production by fusion. The basic idea is to use nuclear energy of the fuel (hydrogen plasma) to produce molecular hydrogen fro carbon-free hydrogen compounds. The hydrogen is then stored and utilized electrochemically in fuel cells or chemically as molecular hydrogen in internal combustion engines

Thermodynamics of ceramic breeder materials for fusion reactors

International Nuclear Information System (INIS)

Goetzmann, O.

1989-05-01

Based on known or deduced phase relationships in ternary lithium oxygen systems such as Li-Al-O, Li-Si-O and Li-Zr-O, the unknown free enthalpy of formation values of ternary compounds are calculated starting from the known data of the compounds of the binary border systems. Criterion for the data assessment is interconsistency of the data of all the compounds within a given multi-component system. With the help of these data the development of partial pressures during the breeding process can be calculated for all the compounds of interest. In order to facilitate a compatibility assessment the quaternary systems Cr-Li-Si-O, Fe-Li-Si-O and Be-Li-Si-O were also investigated and thermodynamic data of pertinent ternary and quaternary compounds determined. Both the partial pressure development and the compatibility behaviour of a lithium containing compound are criteria for its qualification as a breeder material for a fusion reactor. (orig.) [de

Close collisions between light nuclei: Orbiting and fusion

International Nuclear Information System (INIS)

Shapira, D.; Shivakumar, B.; Harmon, B.A.; Ayik, S.

1987-01-01

Our data have demonstrated that in close collisions the two nuclei first form a rotating dinuclear complex (DNC) which can break up into two complex fragments (Orbiting) or evolve into a compound nucleus. The binary fragment yield was found to be significant in contradiction with earlier views which held that whenever nucleus-nucleus capture occurs fusion is a certainty. The time duration of the dinuclear stage and the nature of its evolution into a compound nucleus were studied and a model which describes these processes will be presented. 25 refs., 14 figs

HIV-1 gp41 Fusion Intermediate: A Target for HIV Therapeutics

Directory of Open Access Journals (Sweden)

Chungen Pan

2010-02-01

Full Text Available Human immunodeficiency virus (HIV-1 infection is initiated by the binding of gp120 envelope glyco-protein to its cell receptor (CD4 and a coreceptor (CXCR4 or CCR5, followed by a series of conformational changes in the gp41 transmembrane subunit. These changes include insertion of fusion peptide into the target cell membrane and association of C-heptad repeat (CHR peptide with the N-heptad repeat (NHR trimer, a pre-hairpin fusion intermediate. A stable six-helix bundle core is then formed, bringing the viral envelope and target cell membrane into close proximity for fusion. Peptides derived from the CHR region, such as T20 and C34, inhibit HIV-1 fusion by interacting with the gp41 fusion intermediate. A number of anti-HIV-1 peptides and small molecule compounds targeting the gp41 NHR-trimer have been identified. By combining HIV fusion/entry inhibitors targeting different sites in the gp41 fusion intermediate, a potent synergistic effect takes place, resulting in a potential new therapeutic strategy for the HIV infection/AIDS. Here, we present an overview of the current development of anti-HIV drugs, particularly those targeting the gp41 fusion intermediate.

Surface effects in controlled thermonuclear fusion

International Nuclear Information System (INIS)

Kaminsky, M.

1975-08-01

During the operation of large size plasma facilities and future controlled thermonuclear fusion reactors the surfaces of such major components as container walls, beam limiters, diverter walls and beam-dump walls of the injector region will be exposed to particle and photon bombardment from primary plasma radiations and from secondary radiations. Such radiations can cause, for example, physical and chemical sputtering, blistering, particle- and photon-impact induced desorption, secondary electron and x-ray emission, backscattering, nuclear reactions, photo-decomposition of surface compounds, photocatalysis, and vaporization. Such effects in turn can (a) seriously damage and erode the bombarded surface and (b) release major quantities of impurities which will contaminate the plasma. The effects of some of the major surface phenomena on the operation of plasma facilities and future fusion reactors are discussed

Complete fusion of the 12C+12O, 14N+12C and 15N+12C systems

International Nuclear Information System (INIS)

Conjeaud, M.; Gary, S.; Harar, S.; Wieleczko, J.P.

1978-01-01

Cross sections for evaporation residues following the complete fusion of the 12 C+ 12 C, 14 N+ 12 C and 15 N+ 12 C systems have been measured with a E-ΔE counter telescope in a wide range of incident energies. They are fairly well reproduced by evaporation calculations based on the statistical theory. The total fusion excitation function of the 12 C+ 12 C system shows strong structure, which is compared to the predictions of the reaction cross sections derived from coupled channel calculations and to the integrated inelastic cross sections. Critical angular momenta have been obtained from the fusion cross-section data and these values are discussed in the framework of compound nucleus and entrance channel effects. A striking difference is observed between the fusion cross sections of the 14 N+ 12 C and 15 N+ 12 C systems and shows the importance of the valence nucleons of colliding ions in the fusion process. A possible interpretation might be the influence of the yrast line of the compound nuclei. (Auth.)

Odd-Z Transactinide Compound Nucleus Reactions Including the Discovery of 260Bh

International Nuclear Information System (INIS)

Nelson, Sarah L; Nelson, Sarah L

2008-01-01

Several reactions producing odd-Z transactinide compound nuclei were studied with the 88-Inch Cyclotron and the Berkeley Gas-Filled Separator at the Lawrence Berkeley National Laboratory. The goal was to produce the same compound nucleus at or near the same excitation energy with similar values of angular momentum via different nuclear reactions. In doing so, it can be determined if there is a preference in entrance channel, because under these experimental conditions the survival portion of Swiatecki, Siwek-Wilcznska, and Wilczynski's 'Fusion By Diffusion' model is nearly identical for the two reactions. Additionally, because the same compound nucleus is produced, the exit channel is the same. Four compound nuclei were examined in this study: 258Db, 262Bh, 266Mt, and 272Rg. These nuclei were produced by using very similar heavy-ion induced-fusion reactions which differ only by one proton in the projectile or target nucleus (e.g.: 50Ti + 209Bi vs. 51V + 208Pb). Peak 1n exit channel cross sections were determined for each reaction in each pair, and three of the four pairs; cross sections were identical within statistical uncertainties. This indicates there is not an obvious preference of entrance channel in these paired reactions. Charge equilibration immediately prior to fusion leading to a decreased fusion barrier is the likely cause of this phenomenon. In addition to this systematic study, the lightest isotope of element 107, bohrium, was discovered in the 209Bi(52Cr,n) reaction. 260Bh was found to decay by emission of a 10.16 MeV alpha particle with a half-life of 35 ms. The cross section is 59 pb at an excitation energy of 15.0 MeV. The effect of the N = 152 shell is also seen in this isotope's alpha particle energy, the first evidence of such an effect in Bh. All reactions studied are also compared to model predictions by Swiatecki, Siwek-Wilcznska, and Wilczynski's 'Fusion By Diffusion' theory

Fusion technology programme

International Nuclear Information System (INIS)

Finken, D.

1986-05-01

In 1982, KfK joined the fusion programme of EURATOM as a further association introducing its experience in nuclear technology. KfK closely cooperates with IPP Garching, the two institutions forming a research unit aiming at planning and realization of future development steps of fusion. KfK has combined its forces in the Nuclear Fusion Project (PKF) with participation of several KfK departments to the project tasks. Previous work of KfK in magnetic fusion has addressed mainly superconducting magnets, plasma heating by cluster ions and studies on structural materials. At present, emphasis of our work has concentrated increasingly on the nuclear part, i.e. the first wall and blanket structures and the elements of the tritium extraction and purification system. Associated to this component development are studies of remote maintenance and safety. Most of the actual work addresses NET, the next step to a demonstration of fusion feasibility. NET is supposed to follow JET, the operating plasma physics experiment of Euratom, on the 1990's. Detailed progress of the work in the past half year is described in this report. (orig./GG)

Quantum calculation of dipole excitation in fusion reaction

International Nuclear Information System (INIS)

Simenel, C.; Chomaz, Ph.; De France, G.

2000-01-01

The excitation of the giant dipole resonance by fusion is studied with N/Z asymmetry in the entrance channel. The TDHF solution exhibits a strong dipole vibration which can be associated with a giant vibration along the main axis of a fluctuating prolate shape. The consequences on the gamma-ray emission from hot compound nuclei are discussed. (author)

Increased Arctic Deposition of Persistent Compounds as a Result of the Montreal Protocol

Science.gov (United States)

Young, C.; Pickard, H. M.; De Silva, A. O.; Spencer, C.; Criscitiello, A. S.; Muir, D.; Sharp, M. J.

2017-12-01

Perfluorocarboxylic acids (PFCAs) are among the diverse groups of compounds characterized as persistent organic pollutants. They are toxic, resistant to environmental degradation, and adversely impact human and environmental health. PFCAs with four or fewer carbons, short-chain PFCAs (scPFCAs), are of particular interest because of their increasing levels in the environment, toxicity to plants, and potential for accumulation in some aquatic ecosystems, making them an emerging environmental concern. A minor source of scPFCAs to the Arctic has been shown to be atmospheric transformation of fluoropolymer precursors, followed by deposition. Additional potential sources of scPFCAs to the Arctic are chlorofluorocarbon (CFC)-replacement compounds. Through analysis of an ice core from the Canadian High Arctic, we show that Montreal Protocol-mandated introduction of CFC-replacement compounds for the heat-transfer industry has led to increasing inputs of these scPFCAs to the remote environment. Flux measurements for scPFCAs as a class of contaminants have only been reported in a couple studies to date. Here, we provide the first multi-decadal temporal record of scPFCA deposition, demonstrating a dramatic increase in deposition resulting from emission of CFC-replacements. These results bring to the forefront a need for a holistic approach to environmental risk assessment that considers impacts of replacement substances and degradation products.

Determination of the enthalpy of fusion and thermal diffusivity for ternary Cu_6_0_−_xSn_xSb_4_0 alloys

International Nuclear Information System (INIS)

Zhai, W.; Zhou, K.; Hu, L.; Wei, B.

2016-01-01

Highlights: • The increasing Sn content reduces the liquidus temperature. • High Sn content results in lower enthalpy of fusion by polynomial functions. • The thermal diffusivity drops from the solid toward the semi-solid state. • Undercoolability of alloys with primary Cu_2Sb phase is stronger than others. - Abstract: The liquidus and solidus temperatures, enthalpy of fusion, and the temperature dependence of thermal diffusivity for ternary Cu_6_0_−_xSn_xSb_4_0 alloys were systematically measured by DSC and laser flash methods. It is found that both the liquidus temperature and the enthalpy of fusion decrease with the rise of Sn content, and their relationships with alloy composition were established by polynomial functions. The thermal diffusivity usually drops from the solid toward the semi-solid state. The undercoolability of those liquid Cu_6_0_−_xSn_xSb_4_0 alloys with primary Cu_2Sb solid phase is stronger than the others with primary β(SnSb) intermetallic compound, and the increase of cooling rate facilitates further undercooling. Microstructural observation indicates that both of the primary Cu_2Sb and β(SnSb) intermetallic compounds in ternary Cu_6_0_−_xSn_xSb_4_0 alloys grow in faceted mode, and develop into coarse flakes and polygonal blocks.

Fusion Pore Diameter Regulation by Cations Modulating Local Membrane Anisotropy

Directory of Open Access Journals (Sweden)

Doron Kabaso

2012-01-01

Full Text Available The fusion pore is an aqueous channel that is formed upon the fusion of the vesicle membrane with the plasma membrane. Once the pore is open, it may close again (transient fusion or widen completely (full fusion to permit vesicle cargo discharge. While repetitive transient fusion pore openings of the vesicle with the plasma membrane have been observed in the absence of stimulation, their frequency can be further increased using a cAMP-increasing agent that drives the opening of nonspecific cation channels. Our model hypothesis is that the openings and closings of the fusion pore are driven by changes in the local concentration of cations in the connected vesicle. The proposed mechanism of fusion pore dynamics is considered as follows: when the fusion pore is closed or is extremely narrow, the accumulation of cations in the vesicle (increased cation concentration likely leads to lipid demixing at the fusion pore. This process may affect local membrane anisotropy, which reduces the spontaneous curvature and thus leads to the opening of the fusion pore. Based on the theory of membrane elasticity, we used a continuum model to explain the rhythmic opening and closing of the fusion pore.

Magnetic-fusion energy and computers

International Nuclear Information System (INIS)

Killeen, J.

1982-01-01

The application of computers to magnetic fusion energy research is essential. In the last several years the use of computers in the numerical modeling of fusion systems has increased substantially. There are several categories of computer models used to study the physics of magnetically confined plasmas. A comparable number of types of models for engineering studies are also in use. To meet the needs of the fusion program, the National Magnetic Fusion Energy Computer Center has been established at the Lawrence Livermore National Laboratory. A large central computing facility is linked to smaller computer centers at each of the major MFE laboratories by a communication network. In addition to providing cost effective computing services, the NMFECC environment stimulates collaboration and the sharing of computer codes among the various fusion research groups

Magnetic fusion energy and computers

International Nuclear Information System (INIS)

Killeen, J.

1982-01-01

The application of computers to magnetic fusion energy research is essential. In the last several years the use of computers in the numerical modeling of fusion systems has increased substantially. There are several categories of computer models used to study the physics of magnetically confined plasmas. A comparable number of types of models for engineering studies are also in use. To meet the needs of the fusion program, the National Magnetic Fusion Energy Computer Center has been established at the Lawrence Livermore National Laboratory. A large central computing facility is linked to smaller computer centers at each of the major MFE laboratories by a communication network. In addition to providing cost effective computing services, the NMFECC environment stimulates collaboration and the sharing of computer codes among the various fusion research groups

Nuclear structure and heavy-ion fusion

International Nuclear Information System (INIS)

Stokstad, R.G.

1980-10-01

A series of lectures is presented on experimental studies of heavy-ion fusion reactions with emphasis on the role of nuclear structure in the fusion mechanism. The experiments considered are of three types: the fusion of lighter heavy ions at subcoulomb energies is studied with in-beam γ-ray techniques; the subbarrier fusion of 16 O and 40 Ar with the isotopes of samarium is detected out of beam by x-radiation from delayed activity; and measurements at very high energies, again for the lighter ions, employ direct particle identification of evaporation residues. The experimental data are compared with predictions based on the fusion of two spheres with the only degree of freedom being the separation of the centers, and which interact via potentials that vary smoothly with changes in the mass and charge of the projectile and target. The data exhibit with the isotopes of samarium, a portion of these deviations can be understood in terms of the changing deformation of the target nucleus, but an additional degree of freedom such as neck formation appears necessary. The results on 10 B + 16 O and 12 C + 14 N → 26 Al at high bombarding energies indicate a maximum limiting angular momentum characteristic of the compound nucleus. At lower energies the nuclear structure of the colliding ion seems to affect strongly the cross section for fusion. Measurements made at subbarrier energies for a variety of projectile-target combinations in the 1p and 2s - 1d shell also indicate that the valence nucleons can affect the energy dependence for fusion. About half the systems studied so far have structureless excitation functions which follow a standard prediction. The other half exhibit large variations from this prediction. The possible importance of neutron transfer is discussed. The two-center shell model appears as a promising approach for gaining a qualitative understanding of these phenomena. 95 references, 52 figures, 1 table

Recent developments in heavy-ion fusion reactions around the Coulomb barrier

Directory of Open Access Journals (Sweden)

Hagino K.

2016-01-01

Full Text Available The nuclear fusion is a reaction to form a compound nucleus. It plays an important role in several circumstances in nuclear physics as well as in nuclear astrophysics, such as synthesis of superheavy elements and nucleosynthesis in stars. Here we discuss two recent theoretical developments in heavy-ion fusion reactions at energies around the Coulomb barrier. The first topic is a generalization of the Wong formula for fusion cross sections in a single-channel problem. By introducing an energy dependence to the barrier parameters, we show that the generalized formula leads to results practically indistinguishable from a full quantal calculation, even for light symmetric systems such as 12C+12C, for which fusion cross sections show an oscillatory behavior. We then discuss a semi-microscopic modeling of heavy-ion fusion reactions, which combine the coupled-channels approach to the state-of-the-art nuclear structure calculations for low-lying collective motions. We apply this method to subbarrier fusion reactions of 58Ni+58Ni and 40Ca+58Ni systems, and discuss the role of anharmonicity of the low-lying vibrational motions.

On fusion driven systems (FDS) for transmutation

Energy Technology Data Exchange (ETDEWEB)

Aagren, O (Uppsala Univ., Aangstroem laboratory, div. of electricity, Uppsala (Sweden)); Moiseenko, V.E. (Inst. of Plasma Physics, National Science Center, Kharkov Inst. of Physics and Technology, Kharkov (Ukraine)); Noack, K. (Forschungszentrum Dresden-Rossendorf (Germany))

2008-10-15

This report gives a brief description of ongoing activities on fusion driven systems (FDS) for transmutation of the long-lived radioactive isotopes in the spent nuclear waste from fission reactors. Driven subcritical systems appears to be the only option for efficient minor actinide burning. Driven systems offer a possibility to increase reactor safety margins. A comparatively simple fusion device could be sufficient for a fusion-fission machine, and transmutation may become the first industrial application of fusion. Some alternative schemes to create strong fusion neutron fluxes are presented

On fusion driven systems (FDS) for transmutation

International Nuclear Information System (INIS)

Aagren, O; Moiseenko, V.E.; Noack, K.

2008-10-01

This report gives a brief description of ongoing activities on fusion driven systems (FDS) for transmutation of the long-lived radioactive isotopes in the spent nuclear waste from fission reactors. Driven subcritical systems appears to be the only option for efficient minor actinide burning. Driven systems offer a possibility to increase reactor safety margins. A comparatively simple fusion device could be sufficient for a fusion-fission machine, and transmutation may become the first industrial application of fusion. Some alternative schemes to create strong fusion neutron fluxes are presented

The conserved glycine residues in the transmembrane domain of the Semliki Forest virus fusion protein are not required for assembly and fusion

International Nuclear Information System (INIS)

Liao Maofu; Kielian, Margaret

2005-01-01

The alphavirus Semliki Forest virus (SFV) infects cells via a low pH-triggered fusion reaction mediated by the viral E1 protein. Both the E1 fusion peptide and transmembrane (TM) domain are essential for membrane fusion, but the functional requirements for the TM domain are poorly understood. Here we explored the role of the five TM domain glycine residues, including the highly conserved glycine pair at E1 residues 415/416. SFV mutants with alanine substitutions for individual or all five glycine residues (5G/A) showed growth kinetics and fusion pH dependence similar to those of wild-type SFV. Mutants with increasing substitution of glycine residues showed an increasingly more stringent requirement for cholesterol during fusion. The 5G/A mutant showed decreased fusion kinetics and extent in fluorescent lipid mixing assays. TM domain glycine residues thus are not required for efficient SFV fusion or assembly but can cause subtle effects on the properties of membrane fusion

Fusion energy

International Nuclear Information System (INIS)

Gross, R.A.

1984-01-01

This textbook covers the physics and technology upon which future fusion power reactors will be based. It reviews the history of fusion, reaction physics, plasma physics, heating, and confinement. Descriptions of commercial plants and design concepts are included. Topics covered include: fusion reactions and fuel resources; reaction rates; ignition, and confinement; basic plasma directory; Tokamak confinement physics; fusion technology; STARFIRE: A commercial Tokamak fusion power plant. MARS: A tandem-mirror fusion power plant; and other fusion reactor concepts

Prediction of Positions of Active Compounds Makes It Possible To Increase Activity in Fragment-Based Drug Development

Directory of Open Access Journals (Sweden)

Yoshifumi Fukunishi

2011-05-01

Full Text Available We have developed a computational method that predicts the positions of active compounds, making it possible to increase activity as a fragment evolution strategy. We refer to the positions of these compounds as the active position. When an active fragment compound is found, the following lead generation process is performed, primarily to increase activity. In the current method, to predict the location of the active position, hydrogen atoms are replaced by small side chains, generating virtual compounds. These virtual compounds are docked to a target protein, and the docking scores (affinities are examined. The hydrogen atom that gives the virtual compound with good affinity should correspond to the active position and it should be replaced to generate a lead compound. This method was found to work well, with the prediction of the active position being 2 times more efficient than random synthesis. In the current study, 15 examples of lead generation were examined. The probability of finding active positions among all hydrogen atoms was 26%, and the current method accurately predicted 60% of the active positions.

Economic potential of inertial fusion

International Nuclear Information System (INIS)

Nuckolls, J.H.

1984-04-01

Beyond the achievement of scientific feasibility, the key question for fusion energy is: does it have the economic potential to be significantly cheaper than fission and coal energy. If fusion has this high economic potential then there are compelling commercial and geopolitical incentives to accelerate the pace of the fusion program in the near term, and to install a global fusion energy system in the long term. Without this high economic potential, fusion's success depends on the failure of all alternatives, and there is no real incentive to accelerate the program. If my conjectures on the economic potential of inertial fusion are approximately correct, then inertial fusion energy's ultimate costs may be only half to two-thirds those of advanced fission and coal energy systems. Relative cost escalation is not assumed and could increase this advantage. Both magnetic and inertial approaches to fusion potentially have a two-fold economic advantage which derives from two fundamental properties: negligible fuel costs and high quality energy which makes possible more efficient generation of electricity. The wining approach to fusion may excel in three areas: electrical generating efficiency, minimum material costs, and adaptability to manufacture in automated factories. The winning approach must also rate highly in environmental potential, safety, availability factor, lifetime, small 0 and M costs, and no possibility of utility-disabling accidents

Osteoclast Fusion

DEFF Research Database (Denmark)

Marie Julie Møller, Anaïs; Delaissé, Jean-Marie; Søe, Kent

2017-01-01

on the nuclearity of fusion partners. While CD47 promotes cell fusions involving mono-nucleated pre-osteoclasts, syncytin-1 promotes fusion of two multi-nucleated osteoclasts, but also reduces the number of fusions between mono-nucleated pre-osteoclasts. Furthermore, CD47 seems to mediate fusion mostly through...... individual fusion events using time-lapse and antagonists of CD47 and syncytin-1. All time-lapse recordings have been studied by two independent observers. A total of 1808 fusion events were analyzed. The present study shows that CD47 and syncytin-1 have different roles in osteoclast fusion depending...... broad contact surfaces between the partners' cell membrane while syncytin-1 mediate fusion through phagocytic-cup like structure. J. Cell. Physiol. 9999: 1-8, 2016. © 2016 Wiley Periodicals, Inc....

Increasing low frequency sound attenuation using compounded single layer of sonic crystal

Science.gov (United States)

Gulia, Preeti; Gupta, Arpan

2018-05-01

Sonic crystals (SC) are man-made periodic structures where sound hard scatterers are arranged in a crystalline manner. SC reduces noise in a particular range of frequencies called as band gap. Sonic crystals have a promising application in noise shielding; however, the application is limited due to the size of structure. Particularly for low frequencies, the structure becomes quite bulky, restricting its practical application. This paper presents a compounded model of SC, which has the same overall area and filling fraction but with increased low frequency sound attenuation. Two cases have been considered, a three layer SC and a compounded single layer SC. Both models have been analyzed using finite element simulation and plane wave expansion method. Band gaps for periodic structures have been obtained using both methods which are in good agreement. Further, sound transmission loss has been evaluated using finite element method. The results demonstrate the use of compounded model of Sonic Crystal for low frequency sound attenuation.

Dissolution behavior of lithium compounds in ethanol

Directory of Open Access Journals (Sweden)

Tomohiro Furukawa

2016-12-01

Full Text Available In order to exchange the components which received irradiation damage during the operation at the International Fusion Materials Irradiation Facility, the adhered lithium, which is partially converted to lithium compounds such as lithium oxide and lithium hydroxide, should be removed from the components. In this study, the dissolution experiments of lithium compounds (lithium nitride, lithium hydroxide, and lithium oxide were performed in a candidate solvent, allowing the clarification of time and temperature dependence. Based on the results, a cleaning procedure for adhered lithium on the inner surface of the components was proposed.

A single amino acid substitution in the core protein of West Nile virus increases resistance to acidotropic compounds.

Directory of Open Access Journals (Sweden)

Miguel A Martín-Acebes

Full Text Available West Nile virus (WNV is a worldwide distributed mosquito-borne flavivirus that naturally cycles between birds and mosquitoes, although it can infect multiple vertebrate hosts including horses and humans. This virus is responsible for recurrent epidemics of febrile illness and encephalitis, and has recently become a global concern. WNV requires to transit through intracellular acidic compartments at two different steps to complete its infectious cycle. These include fusion between the viral envelope and the membrane of endosomes during viral entry, and virus maturation in the trans-Golgi network. In this study, we followed a genetic approach to study the connections between viral components and acidic pH. A WNV mutant with increased resistance to the acidotropic compound NH4Cl, which blocks organelle acidification and inhibits WNV infection, was selected. Nucleotide sequencing revealed that this mutant displayed a single amino acid substitution (Lys 3 to Glu on the highly basic internal capsid or core (C protein. The functional role of this replacement was confirmed by its introduction into a WNV infectious clone. This single amino acid substitution also increased resistance to other acidification inhibitor (concanamycin A and induced a reduction of the neurovirulence in mice. Interestingly, a naturally occurring accompanying mutation found on prM protein abolished the resistant phenotype, supporting the idea of a genetic crosstalk between the internal C protein and the external glycoproteins of the virion. The findings here reported unveil a non-previously assessed connection between the C viral protein and the acidic pH necessary for entry and proper exit of flaviviruses.

A single amino acid substitution in the core protein of West Nile virus increases resistance to acidotropic compounds.

Science.gov (United States)

Martín-Acebes, Miguel A; Blázquez, Ana-Belén; de Oya, Nereida Jiménez; Escribano-Romero, Estela; Shi, Pei-Yong; Saiz, Juan-Carlos

2013-01-01

West Nile virus (WNV) is a worldwide distributed mosquito-borne flavivirus that naturally cycles between birds and mosquitoes, although it can infect multiple vertebrate hosts including horses and humans. This virus is responsible for recurrent epidemics of febrile illness and encephalitis, and has recently become a global concern. WNV requires to transit through intracellular acidic compartments at two different steps to complete its infectious cycle. These include fusion between the viral envelope and the membrane of endosomes during viral entry, and virus maturation in the trans-Golgi network. In this study, we followed a genetic approach to study the connections between viral components and acidic pH. A WNV mutant with increased resistance to the acidotropic compound NH4Cl, which blocks organelle acidification and inhibits WNV infection, was selected. Nucleotide sequencing revealed that this mutant displayed a single amino acid substitution (Lys 3 to Glu) on the highly basic internal capsid or core (C) protein. The functional role of this replacement was confirmed by its introduction into a WNV infectious clone. This single amino acid substitution also increased resistance to other acidification inhibitor (concanamycin A) and induced a reduction of the neurovirulence in mice. Interestingly, a naturally occurring accompanying mutation found on prM protein abolished the resistant phenotype, supporting the idea of a genetic crosstalk between the internal C protein and the external glycoproteins of the virion. The findings here reported unveil a non-previously assessed connection between the C viral protein and the acidic pH necessary for entry and proper exit of flaviviruses.

Applying the elastic model for various nucleus-nucleus fusion

International Nuclear Information System (INIS)

HASSAN, G.S.; RAGAB, H.S.; SEDDEEK, M.K.

2000-01-01

The Elastic Model of two free parameters m,d given by Scalia has been used for wider energy regions to fit the available experimental data for potential barriers and cross sections. In order to generalize Scalia's formula in both sub- and above-barrier regions, we calculated m, d for pairs rather than those given by Scalia and compared the calculated cross sections with the experimental data. This makes a generalization of the Elastic Model in describing fusion process. On the other hand, Scalia's range of interacting systems was 24 ≤ A ≤194 where A is the compound nucleus mass number. Our extension of that model includes an example of the pairs of A larger than his final limit aiming to make it as a general formula for any type of reactants: light, intermediate or heavy systems. A significant point is the comparison of Elastic Model calculations with the well known methods studying complete fusion and compound nucleus formation, namely with the resultants of using Proximity potential with either Sharp or Smooth cut-off approximations

West European magnetic confinement fusion research

International Nuclear Information System (INIS)

McKenney, B.L.; McGrain, M.; Hogan, J.T.; Porkolab, M.; Thomassen, K.I.

1990-01-01

This report presents a technical assessment and review of the West European program in magnetic confinement fusion by a panel of US scientists and engineers active in fusion research. Findings are based on the scientific and technical literature, on laboratory reports and preprints, and on the personal experiences and collaborations of the panel members. Concerned primarily with developments during the past 10 years, from 1979 to 1989, the report assesses West European fusion research in seven technical areas: tokamak experiments; magnetic confinement technology and engineering; fusion nuclear technology; alternate concepts; theory; fusion computations; and program organization. The main conclusion emerging from the analysis is that West European fusion research has attained a position of leadership in the international fusion program. This distinction reflects in large measure the remarkable achievements of the Joint European Torus (JET). However, West European fusion prominence extends beyond tokamak experimental physics: the program has demonstrated a breadth of skill in fusion science and technology that is not excelled in the international effort. It is expected that the West European primacy in central areas of confinement physics will be maintained or even increased during the early 1990s. The program's maturity and commitment kindle expectations of dramatic West European advances toward the fusion energy goal. For example, achievement of fusion breakeven is expected first in JET, before 1995

Cold fusion catalyzed by muons and electrons

International Nuclear Information System (INIS)

Kulsrud, R.M.

1990-10-01

Two alternative methods have been suggested to produce fusion power at low temperature. The first, muon catalyzed fusion or MCF, uses muons to spontaneously catalyze fusion through the muon mesomolecule formation. Unfortunately, this method fails to generate enough fusion energy to supply the muons, by a factor of about ten. The physics of MCF is discussed, and a possible approach to increasing the number of MCF fusions generated by each muon is mentioned. The second method, which has become known as ''Cold Fusion,'' involves catalysis by electrons in electrolytic cells. The physics of this process, if it exists, is more mysterious than MCF. However, it now appears to be an artifact, the claims for its reality resting largely on experimental errors occurring in rather delicate experiments. However, a very low level of such fusion claimed by Jones may be real. Experiments in cold fusion will also be discussed

Fusion

CERN Document Server

Mahaffey, James A

2012-01-01

As energy problems of the world grow, work toward fusion power continues at a greater pace than ever before. The topic of fusion is one that is often met with the most recognition and interest in the nuclear power arena. Written in clear and jargon-free prose, Fusion explores the big bang of creation to the blackout death of worn-out stars. A brief history of fusion research, beginning with the first tentative theories in the early 20th century, is also discussed, as well as the race for fusion power. This brand-new, full-color resource examines the various programs currently being funded or p

Fusion energy and nuclear liability considerations

International Nuclear Information System (INIS)

Fork, William E.; Peterson, Charles H.

2014-01-01

For over 60 years, fusion energy has been recognised as a promising technology for safe, secure and environmentally-sustainable commercial electrical power generation. Over the past decade, research and development programmes across the globe have shown progress in developing critical underlying technologies. Approaches ranging from high-temperature plasma magnetic confinement fusion to inertial confinement fusion are increasingly better understood. As scientific research progresses in its aim to achieve fusion 'ignition', where nuclear fusion becomes self-sustaining, the international legal community should consider how fusion power technologies fit within the current nuclear liability legal framework. An understanding of the history of the civil nuclear liability regimes, along with the different risks associated with fusion power, will enable nations to consider the proper legal conditions needed to deploy and commercialise fusion technologies for civil power generation. This note is divided into three substantive parts. It first provides background regarding fusion power and describes the relatively limited risks of fusion technologies when compared with traditional nuclear fission technologies. It then describes the international nuclear liability regime and analyses how fusion power fits within the text of the three leading conventions. Finally, it examines how fusion power may fall within the international nuclear liability framework in the future, a discussion that includes possible amendments to the relevant international liability conventions. It concludes that the unique nature of the current civil nuclear liability regime points towards the development of a more tailored liability solution because of the reduced risks associated with fusion power. (authors)

Fusion research in Hungary

International Nuclear Information System (INIS)

Zoletnik, S.

2004-01-01

Hungarian fusion research started in the 1970s, when the idea of installing a small tokamak experiment emerged. In return to computer equipment a soviet tokamak was indeed sent to Hungary and started to operate as MT-1 at the Central Research Institute for Physics (KFKI) in 1979. Major research topics included diagnostic development, edge plasma studies and investigation of disruptions. Following a major upgrade in 1992 (new vacuum vessel, active position control and PC network based data acquisition system) the MT-1M tokamak was used for the study of transport processes with trace impurity injection, micropellet ablation studies, X-ray tomography and laser blow-off diagnostic development. Although funding ceased in the middle of the 90's the group was held alive by collaborations with EU fusion labs: FZ -Juelich, IPP-Garching and CRPP-EPFL Lausanne. In 1998 the machine was dismantled due to reorganization of the Hungarian Academy of Sciences. New horizons opened to fusion research from 1999, when Hungary joined EURATOM and a fusion Association was formed. Since then fusion physics studies are done in collaboration with major EU fusion laboratories, Hungarian researchers also play an active role in JET diagnostics upgrade and ITER design. Major topics are pellet ablation studies, plasma turbulence diagnosis using Beam Emission Spectroscopy and other techniques, tomography and plasma diagnostics using various neutral beams. In fusion relevant technology R and D Hungary has less records. Before joining EURATOM some materials irradiation studies were done at the Budapest Research Reactor at KFKI-AEKI. The present day fusion technology programme focuses still on irradiation studies, nuclear material database and electromagnetic testing techniques. Increasing the fusion technology research activities is a difficult task, as the competition in Hungarian industry is very strong and the interest of organizations in long-term investments into R and D is rather weak and

Wetting properties of liquid lithium on lithium compounds

Energy Technology Data Exchange (ETDEWEB)

Krat, S.A., E-mail: stepan.krat@gmail.com [Center for Plasma Material Interactions, Department of Nuclear, Plasma, and Radiological Engineering, University Illinois at Urbana-Champaign, Urbana (United States); National Research Nuclear University MEPhI, Moscow (Russian Federation); Popkov, A.S. [Center for Plasma Material Interactions, Department of Nuclear, Plasma, and Radiological Engineering, University Illinois at Urbana-Champaign, Urbana (United States); National Research Nuclear University MEPhI, Moscow (Russian Federation); Gasparyan, Yu. M.; Pisarev, A.A. [National Research Nuclear University MEPhI, Moscow (Russian Federation); Fiflis, Peter; Szott, Matthew; Christenson, Michael; Kalathiparambil, Kishor; Ruzic, David N. [Center for Plasma Material Interactions, Department of Nuclear, Plasma, and Radiological Engineering, University Illinois at Urbana-Champaign, Urbana (United States)

2017-04-15

Highlights: • Contact angles of liquid lithium and Li{sub 3}N, Li{sub 2}O, Li{sub 2}CO{sub 3} were measured. • Liquid lithium wets lithium compounds at relatively low temperatures: Li{sub 3}N at 257 °C, Li{sub 2}O at 259 °C, Li{sub 2}CO{sub 3} at 323 °C. • Li wets Li{sub 2}O and Li{sub 3}N better than previously measured fusion-relevant materials (W, Mo, Ta, TZM, stainless steel). • Li wets Li{sub 2}CO{sub 3} better than most previously measured fusion-relevant materials (W, Mo, Ta). - Abstract: Liquid metal plasma facing components (LMPFC) have shown a potential to supplant solid plasma facing components materials in the high heat flux regions of magnetic confinement fusion reactors due to the reduction or elimination of concerns over melting, wall damage, and erosion. To design a workable LMPFC, one must understand how liquid metal interacts with solid underlying structures. Wetting is an important factor in such interaction, several designs of LMPFC require liquid metal to wet the underlying solid structures. The wetting of lithium compounds (lithium nitride, oxide, and carbonate) by 200 °C liquid lithium at various surface temperature from 230 to 330 °C was studied by means of contact angle measurements. Wetting temperatures, defined as the temperature above which the contact angle is less than 90°, were measured. The wetting temperature was 257 °C for nitride, 259 °C for oxide, and 323 °C for carbonate. Surface tensions of solid lithium compounds were calculated from the contact angle measurements.

The preliminary research for biosynthetic engineering by radiation fusion technology

Energy Technology Data Exchange (ETDEWEB)

Roh, Chang Hyun; Jung, U Hee; Park, Hae Ran [KAERI, Daejeon (Korea, Republic of)

2012-01-15

The purpose of this project is to elucidate the solution to the production of bioactive substance using biotransformation process from core technology of biosynthetic engineering by radiation fusion technology. And, this strategy will provide core technology for development of drugs as new concept and category. Research scopes and contents of project include 1) The development of mutant for biosynthetic engineering by radiation fusion technology 2) The development of host for biosynthetic engineering by radiation fusion technology 3) The preliminary study for biosynthetic engineering of isoflavone by radiation fusion technology. The results are as follows. Isoflavone compounds(daidzein, hydroxylated isoflavone) were analyzed by GC-MS. The study of radiation doses and p-NCA high-throughput screening for mutant development were elucidated. And, it was carried out the study of radiation doses for host development. Furthermore, the study of redox partner and construction of recombinant strain for region-specific hydroxylation(P450, redox partner). In addition, the biological effect of 6,7,4'-trihydroxyisoflavone as an anti-obesity agent was elucidated in this study.

Organic materials for fusion-reactor applications

International Nuclear Information System (INIS)

Hurley, G.F.; Coltman, R.R. Jr.

1983-09-01

Organic materials requirements for fusion-reactor magnets are described with reference to the temperature, radiation, and electrical and mechanical stress environment expected in these magnets. A review is presented of the response to gamma-ray and neutron irradiation at low temperatures of candidate organic materials; i.e. laminates, thin films, and potting compounds. Lifetime-limiting features of this response as well as needed testing under magnet operating conditions not yet adequately investigated are identified and recomendations for future work are made

Inertial fusion: strategy and economic potential

International Nuclear Information System (INIS)

Nuckolls, J.H.

1983-01-01

Inertial fusion must demonstrate that the high target gains required for practical fusion energy can be achieved with driver energies not larger than a few megajoules. Before a multi-megajoule scale driver is constructed, inertial fusion must provide convincing experimental evidence that the required high target gains are feasible. This will be the principal objective of the NOVA laser experiments. Implosions will be conducted with scaled targets which are nearly hydrodynamically equivalent to the high gain target implosions. Experiments which demonstrate high target gains will be conducted in the early nineties when multi-megajoule drivers become available. Efficient drivers will also be demonstrated by this time period. Magnetic fusion may demonstrate high Q at about the same time as inertial fusion demonstrates high gain. Beyond demonstration of high performance fusion, economic considerations will predominate. Fusion energy will achieve full commercial success when it becomes cheaper than fission and coal. Analysis of the ultimate economic potential of inertial fusion suggests its costs may be reduced to half those of fission and coal. Relative cost escalation would increase this advantage. Fusions potential economic advantage derives from two fundamental properties: negligible fuel costs and high quality energy (which makes possible more efficient generation of electricity)

Muon nuclear fusion and low temperature nuclear fusion

International Nuclear Information System (INIS)

Nagamine, Kanetada

1990-01-01

Low temperature (or normal temperature) nuclear fusion is one of the phenomena causing nuclear fusion without requiring high temperature. In thermal nuclear fusion, the Coulomb barrier is overcome with the help of thermal energy, but in the low temperature nuclear fusion, the Coulomb barrier is neutralized by the introduction of the particles having larger mass than electrons and negative charges, at this time, if two nuclei can approach to the distance of 10 -13 cm in the neutral state, the occurrence of nuclear fusion reaction is expected. As the mass of the particles is heavier, the neutral region is smaller, and nuclear fusion is easy to occur. The particles to meet this purpose are the electrons within substances and muons. The research on muon nuclear fusion became suddenly active in the latter half of 1970s, the cause of which was the discovery of the fact that the formation of muons occurs resonantly rapidly in D-T and D-D systems. Muons are the unstable elementary particles having the life of 2.2 μs, and they can have positive and negative charges. In the muon catalyzed fusion, the muons with negative charge take part. The principle of the muon catalyzed fusion, its present status and future perspective, and the present status of low temperature nuclear fusion are reported. (K.I.)

Investigations of image fusion

Science.gov (United States)

Zhang, Zhong

1999-12-01

The objective of image fusion is to combine information from multiple images of the same scene. The result of image fusion is a single image which is more suitable for the purpose of human visual perception or further image processing tasks. In this thesis, a region-based fusion algorithm using the wavelet transform is proposed. The identification of important features in each image, such as edges and regions of interest, are used to guide the fusion process. The idea of multiscale grouping is also introduced and a generic image fusion framework based on multiscale decomposition is studied. The framework includes all of the existing multiscale-decomposition- based fusion approaches we found in the literature which did not assume a statistical model for the source images. Comparisons indicate that our framework includes some new approaches which outperform the existing approaches for the cases we consider. Registration must precede our fusion algorithms. So we proposed a hybrid scheme which uses both feature-based and intensity-based methods. The idea of robust estimation of optical flow from time- varying images is employed with a coarse-to-fine multi- resolution approach and feature-based registration to overcome some of the limitations of the intensity-based schemes. Experiments show that this approach is robust and efficient. Assessing image fusion performance in a real application is a complicated issue. In this dissertation, a mixture probability density function model is used in conjunction with the Expectation- Maximization algorithm to model histograms of edge intensity. Some new techniques are proposed for estimating the quality of a noisy image of a natural scene. Such quality measures can be used to guide the fusion. Finally, we study fusion of images obtained from several copies of a new type of camera developed for video surveillance. Our techniques increase the capability and reliability of the surveillance system and provide an easy way to obtain 3-D

Determination of vapor pressures, enthalpies of sublimation, and enthalpies of fusion of benzenetriols

International Nuclear Information System (INIS)

Verevkin, Sergey P.; Schick, Christoph

2004-01-01

Molar enthalpies of sublimation of 1,2,4-, 1,2,3-, and 1,3,5-tri-hydroxy-benzene, were obtained from the temperature dependence of the vapor pressure measured by the transpiration method. The molar enthalpies of fusion and molar heat capacities of these compounds were measured by DSC. The measured data sets of vaporization, sublimation and fusion enthalpies were checked for internal consistency. Strength of the inter- and intra-molecular hydrogen bonding in di- and tri-hydroxy-benzenes have been assessed

Fusion energy using avalanche increased boron reactions for block-ignition by ultrahigh power picosecond laser pulses

Czech Academy of Sciences Publication Activity Database

Hora, H.; Korn, Georg; Giuffrida, Lorenzo; Margarone, Daniele; Picciotto, A.; Krása, Josef; Jungwirth, Karel; Ullschmied, Jiří; Lalousis, P.; Eliezer, S.; Miley, G. H.; Moustaizis, S.; Mourou, G.

2015-01-01

Roč. 33, č. 4 (2015), s. 607-619 ISSN 0263-0346 Institutional support: RVO:68378271 ; RVO:61389021 Keywords : fusion energy without radiation problem * boron fusion by lasers * non-linear force-driven block ignition Subject RIV: BL - Plasma and Gas Discharge Physics; BH - Optics, Masers, Lasers (UFP-V) Impact factor: 1.649, year: 2015

Microscopic study on dynamic barrier in fusion reactions

International Nuclear Information System (INIS)

Wu Xizhen; Tian Junlong; Zhao Kai; Li Zhuxia; Wang Ning

2004-01-01

The authors briefly review the fusion process of very heavy nuclear systems and some theoretical models. The authors propose a microscopic transport dynamic model, i.e. the Improved Quantum Molecular Dynamic model, for describing fusion reactions of heavy systems, in which the dynamical behavior of the fusion barrier in heavy fusion systems has been studied firstly. The authors find that with the incident energy decreasing the lowest dynamic barrier is obtained which approaches to the adiabatic static barrier and with increase of the incident energy the dynamic barrier goes up to the diabatic static barrier. The authors also indicate that how the dynamical fusion barrier is correlated with the development of the configuration of fusion partners along the fusion path. Associating the single-particle potentials obtained at different stages of fusion with the Two Center Shell Model, authors can study the time evolution of the single particle states of fusion system in configuration space of single particle orbits along the fusion path. (author)

Porous calcium carbonate as a carrier material to increase the dissolution rate of poorly soluble flavouring compounds.

Science.gov (United States)

Lundin Johnson, Maria; Noreland, David; Gane, Patrick; Schoelkopf, Joachim; Ridgway, Cathy; Millqvist Fureby, Anna

2017-04-19

Two different food grade functionalised porous calcium carbonates (FCC), with different pore size and pore size distributions, were characterised and used as carrier materials to increase the dissolution rate of poorly soluble flavouring compounds in aqueous solution. The loading level was varied between 1.3% by weight (wt%) and 35 wt%, where the upper limit of 35 wt% was the total maximum loading capacity of flavouring compound in FCC based on the fraction of the total weight of FCC plus flavouring compound. Flavouring compounds (l-carvone, vanillin, and curcumin) were selected based on their difference in hydrophilicity and capacity to crystallise. Release kinetic studies revealed that all flavouring compounds showed an accelerated release when loaded in FCC compared to dissolution of the flavouring compound itself in aqueous medium. The amorphous state and/or surface enlargement of the flavouring compound inside or on FCC explains the faster release. The flavouring compounds capable of crystallising (vanillin and curcumin) were almost exclusively amorphous within the porous FCC material as determined by X-ray powder diffraction one week after loading and after storing the loaded FCC material for up to 9 months at room temperature. A small amount of crystalline vanillin and curcumin was detected in the FCC material with large pores and high flavouring compound loading (≥30 wt%). Additionally, two different loading strategies were evaluated, loading by dissolving the flavouring compound in acetone or loading by a hot melt method. Porosimetry data showed that the melt method was more efficient in filling the smallest pores (<100 nm). The main factor influencing the release rate appears to be the amorphous state of the flavouring compound and the increase in exposed surface area. The confinement in small pores prevents crystallisation of the flavouring compounds during storage, providing a stable amorphous form retaining high release rate also after storage.

Increasing the magnetic-field capability of the magneto-inertial fusion electrical discharge system using an inductively coupled coil

Science.gov (United States)

Barnak, D. H.; Davies, J. R.; Fiksel, G.; Chang, P.-Y.; Zabir, E.; Betti, R.

2018-03-01

Magnetized high energy density physics (HEDP) is a very active and relatively unexplored field that has applications in inertial confinement fusion, astrophysical plasma science, and basic plasma physics. A self-contained device, the Magneto-Inertial Fusion Electrical Discharge System, MIFEDS [G. Fiksel et al., Rev. Sci. Instrum. 86, 016105 (2015)], was developed at the Laboratory for Laser Energetics to conduct magnetized HEDP experiments on both the OMEGA [T. R. Boehly et al., Opt. Commun. 133, 495-506 (1997)] and OMEGA EP [J. H. Kelly et al., J. Phys. IV France 133, 75 (2006) and L. J. Waxer et al., Opt. Photonics News 16, 30 (2005)] laser systems. Extremely high magnetic fields are a necessity for magnetized HEDP, and the need for stronger magnetic fields continues to drive the redevelopment of the MIFEDS device. It is proposed in this paper that a magnetic coil that is inductively coupled rather than directly connecting to the MIFEDS device can increase the overall strength of the magnetic field for HEDP experiments by increasing the efficiency of energy transfer while decreasing the effective magnetized volume. A brief explanation of the energy delivery of the MIFEDS device illustrates the benefit of inductive coupling and is compared to that of direct connection for varying coil size and geometry. A prototype was then constructed to demonstrate a 7-fold increase in energy delivery using inductive coupling.

The economic value of fusion energy

International Nuclear Information System (INIS)

Kim, S.H.; Clarke, J.; Edmonds, J.

1996-01-01

The potential economic benefit of fusion energy technology is significant and could dwarf the world's total expenditure on fusion energy research and development. However, the realization of these benefits will depend on the economic competitiveness of electricity generation from fusion energy technologies relative to that from other existing fossil fueled and renewable technologies, as well as the time in which fusion energy technologies are available for commercial operation. Utilizing the Second Generation Model, a long-term energy/economics model, the potential economic benefit of fusion energy technology for the United States was assessed. Model scenarios with hypothetical fusion power technologies based on the International Thermonuclear Experimental Reactor (ITER) design with varying cost and time of availability showed that significant economic benefit exists from a competitive fusion technology with cost of electricity (COE) of 0.06 $/kWhr and available in the year 2025. The fusion technology with these characteristics resulted in a total discounted GDP benefit of $105 billion from the year 1995 to 2100. On the other hand, uncompetitive fusion technologies with higher COE of 0.12 and 0.09 $/kWhr had little economic benefits. Moreover, delaying the introduction of all fusion technologies from 2025 to 2050 reduced the economic benefits of fusion technologies by more than 60 percent. Aside from the economic benefit of fusion technologies operating in the United States, the potential economic value of international trade in fusion technologies is likely to be even greater. If the United States could capture just a portion of the global electricity market, the export value of the fusion technology could amount to hundreds of billions of dollars, whereas the cost of importing the technology to the United States will erase any benefits derived from GDP increases

The need for fusion

International Nuclear Information System (INIS)

Llewellyn Smith, Chris

2005-01-01

World energy use is predicted to double in the next 40 years. Currently 80% is provided by burning fossil fuels, but this is not sustainable indefinitely because (i) it is driving climate change, and (ii) fossil fuels will eventually be exhausted (starting with oil). The resulting potential energy crisis requires increased investment in energy research and development (which is currently very small on the scale of the $3 trillion p.a. energy market, and falling). The wide portfolio of energy work that should be supported must include fusion, which is one of the very few options that are capable in principle of supplying a large fraction of need. The case for fusion has been strengthened by recent advances in plasma physics and fusion technology that are reflected in the forthcoming European Fusion Power Plant Conceptual Study, which addresses safety and cost issues. The big questions are - How can we deliver fusion power as fast as possible? How long is it likely to take? I argue for a fast track programme, and describe a fast-track model developed at Culham, which is intended to stimulate debate on the way ahead and the resources that are needed

Fusion probability and survivability in estimates of heaviest nuclei production

International Nuclear Information System (INIS)

Sagaidak, Roman

2012-01-01

A number of theoretical models have been recently developed to predict production cross sections for the heaviest nuclei in fusion-evaporation reactions. All the models reproduce cross sections obtained in experiments quite well. At the same time they give fusion probability values P fus ≡ P CN differed within several orders of the value. This difference implies a corresponding distinction in the calculated values of survivability. The production of the heaviest nuclei (from Cm to the region of superheavy elements (SHE) close to Z = 114 and N = 184) in fusion-evaporation reactions induced by heavy ions has been considered in a systematic way within the framework of the barrier-passing (fusion) model coupled with the standard statistical model (SSM) of the compound nucleus (CN) decay. Both models are incorporated into the HIVAP code. Available data on the excitation functions for fission and evaporation residues (ER) produced in very asymmetric combinations can be described rather well within the framework of HIVAP. Cross-section data obtained in these reactions allow one to choose model parameters quite definitely. Thus one can scale and fix macroscopic (liquid-drop) fission barriers for nuclei involved in the evaporation-fission cascade. In less asymmetric combinations (with 22 Ne and heavier projectiles) effects of fusion suppression caused by quasi-fission are starting to appear in the entrance channel of reactions. The P fus values derived from the capture-fission and fusion-fission cross-sections obtained at energies above the Bass barrier were plotted as a function of the Coulomb parameter. For more symmetric combinations one can deduce the P fus values semi-empirically, using the ER and fission excitation functions measured in experiments, and applying SSM model with parameters obtained in the analysis of a very asymmetric combination leading to the production of (nearly) the same CN, as was done for reactions leading to the pre-actinide nuclei formation

Fusion technology: The Iter fusion experiment

International Nuclear Information System (INIS)

Dietz, K.J.

1994-01-01

Plans for the Iter international fusion experiment, in which the European Union, Japan, Canada, Russia, Sweden, Switzerland, and the USA cooperate, were begun in 1985, and construction work started in early 1994. These activities serve for the preparation of the design and construction documents for a research reactor in which a stable fusion plasma is to be generated. This is to be the basis for the construction of a fusion reactor for electricity generation. Preparatory work was performed in the Tokamak experiments with JET and TFTR. The fusion power of 1.5 GW will be attained, thus enabling Iter to keep a deuterium-tritium plasma burning. (orig.) [de

Fusion Physics

Energy Technology Data Exchange (ETDEWEB)

Kikuchi, Mitsuru; Lackner, Karl; Tran, Minh Quang [eds.

2012-09-15

Recreating the energy production process of the Sun - nuclear fusion - on Earth in a controlled fashion is one of the greatest challenges of this century. If achieved at affordable costs, energy supply security would be greatly enhanced and environmental degradation from fossil fuels greatly diminished. Fusion Physics describes the last fifty years or so of physics and research in innovative technologies to achieve controlled thermonuclear fusion for energy production. The International Atomic Energy Agency (IAEA) has been involved since its establishment in 1957 in fusion research. It has been the driving force behind the biennial conferences on Plasma Physics and Controlled Thermonuclear Fusion, today known as the Fusion Energy Conference. Hosted by several Member States, this biennial conference provides a global forum for exchange of the latest achievements in fusion research against the backdrop of the requirements for a net energy producing fusion device and, eventually, a fusion power plant. The scientific and technological knowledge compiled during this series of conferences, as well as by the IAEA Nuclear Fusion journal, is immense and will surely continue to grow in the future. It has led to the establishment of the International Thermonuclear Experimental Reactor (ITER), which represents the biggest experiment in energy production ever envisaged by humankind.

Preparation of Tritium from irradiated lithium compounds (study)

International Nuclear Information System (INIS)

1989-01-01

The aim of the present study is the selection of a certain scheme for release, collection, measurement and analysis of Tritium as produced in Lithium compounds (Li 2 O, LiOH, Li 2 CO 3 LiF and some Lithium alloys) in accordance with the 6 Li(n, α)T reaction. Tritium technology is of vital concern to power reactor programmes as well as to fusion technology. Meanwhile the fields of activity include, tritium generation and mangement in fission and fusion reactors; enviromental studies, release modeling HT/HTO conversion and dose assessments, absorption/ deabsorption, monitoring and plant design; research and development, labeling, compatibility and physical chemical properties

Preparation of Tritium from irradiated lithium compounds (study)

Energy Technology Data Exchange (ETDEWEB)

1989-01-01

The aim of the present study is the selection of a certain scheme for release, collection, measurement and analysis of Tritium as produced in Lithium compounds (Li[sub 2]O, LiOH, Li[sub 2]CO[sub 3] LiF and some Lithium alloys) in accordance with the [sup 6]Li(n, [alpha])T reaction. Tritium technology is of vital concern to power reactor programmes as well as to fusion technology. Meanwhile the fields of activity include, tritium generation and mangement in fission and fusion reactors; enviromental studies, release modeling HT/HTO conversion and dose assessments, absorption/ deabsorption, monitoring and plant design; research and development, labeling, compatibility and physical chemical properties.

Industry perspectives on future directions in the fusion program

International Nuclear Information System (INIS)

Maniscalco, J.A.; Bell, J.M.

1985-01-01

Industry is the ultimate recipient of the product of the fusion development program. However, budget trends are causing the program to lose it's focus on the energy goal, thus diminishing opportunities for a meaningful industrial role at a time when technical progress has been remarkable and scientific feasibility is being demonstrated. The findings of the Magnetic Fusion Advisory Committee Panel charged to report on industrial participation in fusion energy development are summarized. A recommendation of this panel was to increase intellectual involvement of industry in the development of fusion. Opportunities to achieve this include forming partnerships with national laboratories and universities, assigning industry responsibility for a complete scope of work, and assigning industry a major role in system studies and reactor design. These opportunities can be implemented without requiring large budget increases. Increasing the involvement of industry in the fusion program will provide both long and short-term benefits

On the criterion for the optimum choice of a compound nucleus reaction for producing superheavy elements

International Nuclear Information System (INIS)

Aroumougame, R.; Gupta, R.K.

1979-01-01

The possible reaction partners of a cool compound nucleus reaction for the synthesis of the elements Z = 104, 106 and 108 are studied in terms of the potential energy surfaces, interaction barriers and the nuclear shapes calculated within the frame work of the Fragmentation theory based on two centre shell model. An estimate of the total reaction cross-section suggests that for larger fusion probabilities, the mass and charge asymmetries are the only essential criterion for the optimum choice of a cooler compound nuclear reaction. Larger the mass and charge asymmetries, larger is the fusion cross-section. (auth.)

Bringing together fusion research

International Nuclear Information System (INIS)

Leiser, M.

1982-01-01

The increasing involvement of the IAEA in fusion, together with the growing efforts devoted to this area, are described. The author puts forward the idea that one of the most important aspects of this involvement is in providing a world-wide forum for scientists. The functions of the IFRC (International Fusion Research Council) as an advisory group are outlined, and the role played by IFRC in the definition and objectives of INTOR (International Tokamak Reactor) are briefly described

Materials needs for compact fusion reactors

International Nuclear Information System (INIS)

Krakowski, R.A.

1983-01-01

The economic prospects for magnetic fusion energy can be dramatically improved if for the same total power output the fusion neutron first-wall (FW) loading and the system power density can be increased by factors of 3 to 5 and 10 to 30, respectively. A number of compact fusion reactor embodiments have been proposed, all of which would operate with increased FW loadings, would use thin (0.5 to 0.6 m) blankets, and would confine quasi-steady-state plasma with resistive, water-cooled copper or aluminum coils. Increased system power density (5 to 15 MWt/m 3 versus 0.3 to 0.5 MW/m 3 ), considerably reduced physical size of the fusion power core (FPC), and appreciably reduced economic leverage exerted by the FPC and associated physics result. The unique materials requirements anticipated for these compact reactors are outlined against the well documented backdrop provided by similar needs for the mainline approaches. Surprisingly, no single materials need that is unique to the compact systems is identified; crucial uncertainties for the compact approaches must also be addressed by the mainline approaches, particularly for in-vacuum components (FWs, limiters, divertors, etc.)

Rigid amphipathic fusion inhibitors demonstrate antiviral activity against African swine fever virus.

Science.gov (United States)

Hakobyan, Astghik; Galindo, Inmaculada; Nañez, Almudena; Arabyan, Erik; Karalyan, Zaven; Chistov, Alexey A; Streshnev, Philipp P; Korshun, Vladimir A; Alonso, Covadonga; Zakaryan, Hovakim

2018-01-01

Rigid amphipathic fusion inhibitors (RAFIs) are a family of nucleoside derivatives that inhibit the infectivity of several enveloped viruses by interacting with virion envelope lipids and inhibiting fusion between viral and cellular membranes. Here we tested the antiviral activity of two RAFIs, 5-(Perylen-3-ylethynyl)-arabino-uridine (aUY11) and 5-(Perylen-3-ylethynyl)uracil-1-acetic acid (cm1UY11) against African swine fever virus (ASFV), for which no effective vaccine is available. Both compounds displayed a potent, dose-dependent inhibitory effect on ASFV infection in Vero cells. The major antiviral effect was observed when aUY11 and cm1UY11 were added at early stages of infection and maintained during the complete viral cycle. Furthermore, virucidal assay revealed a significant extracellular anti-ASFV activity for both compounds. We also found decrease in the synthesis of early and late viral proteins in Vero cells treated with cm1UY11. Finally, the inhibitory effect of aUY11 and cm1UY11 on ASFV infection in porcine alveolar macrophages was confirmed. Overall, our study has identified novel anti-ASFV compounds with potential for future therapeutic developments.

Study of the effect of {sup 11}Be halo on the sub-coulombian fusion; Etude de l`effet du halo du {sup 11}Be sur la fusion sous-coulombienne

Energy Technology Data Exchange (ETDEWEB)

Felou Youmbi, V

1996-12-11

Fission cross sections of {sup 9,11}Be + {sup 238}U systems are measured in the energy range of the coulomb barrier. These measures allow the study of neutron halo effect on sub coulombian fusion. {sup 9,11}Be beams are obtained by fragmentation at the GANIL facilities. The fusion between incident particle and the target nucleus leads to a compound nucleus which disappears by fission. The FUSION detector is used to detect the fission fragments by coincidence. We present some calculations of potential barriers by using Wong formula. The nucleus-nucleus interaction is simulated by a double convolution between the nucleus density and the effective M3Y interaction. In a more realistic framework ECIS94 code calculates the fusion cross section by using a coupling formalism. Theoretical values and experimental results are compared. We get a good agreement for {sup 9}Be + {sup 238}U system and an unusual behaviour appears for {sup 11}Be + {sup 238}U system 116 refs.

EMP Fusion

OpenAIRE

KUNTAY, Isık

2010-01-01

This paper introduces a novel fusion scheme, called EMP Fusion, which has the promise of achieving breakeven and realizing commercial fusion power. The method is based on harnessing the power of an electromagnetic pulse generated by the now well-developed flux compression technology. The electromagnetic pulse acts as a means of both heating up the plasma and confining the plasma, eliminating intermediate steps. The EMP Fusion device is simpler compared to other fusion devices and this reduces...

The economic viability of fusion power

International Nuclear Information System (INIS)

Ward, D.J.; Cook, I.; Lechon, Y.; Saez, R.

2005-01-01

Although fusion power is being developed because of its large resource base, low environmental impact and high levels of intrinsic safety, it is important to investigate the economics of a future fusion power plant to check that the electricity produced can, in fact, have a market. The direct cost of electricity of a fusion power plant and its key dependencies on the physics and technology assumptions, are calculated, as are the materials requirements. The other important aspect of costs, the external costs which can arise from effects such as pollution, accidents and waste are also given. Fusion is found to offer the prospect of a new energy source with acceptable direct costs and very low external costs. This places fusion in a strong position in a future energy market, especially one in which environmental constraints become increasingly important

TMX: a new fusion plasma experiment

International Nuclear Information System (INIS)

Anon.

1977-01-01

The primary goal of the magnetic fusion energy program at LLL is the development of a technically and economically feasible approach to the generation of fusion energy. Results from our earlier 2XIIB experiment lead us to believe that a fusion power plant based on a mirror system is technically feasible, assuming a favorable extrapolation to plasmas of reactor size. Achieving economic feasibility is more difficult. For power-producing applications, a reactor needs a large Q, the ratio of fusion power output to the power injected to sustain the system. In a conventional mirror reactor, the fusion power is only about equal to the power injected by the neutral beams--that is, Q is only about unity. A new idea, the tandem mirror concept described in this article, promises to increase this gain, enhancing Q by at least a factor of 5

Accelerated plan to develop magnetic fusion energy

International Nuclear Information System (INIS)

Fowler, T.K.

1986-01-01

We have shown that, despite funding delays since the passage of the Magnetic Fusion Engineering Act of 1980, fusion development could still be carried to the point of a demonstration plant by the year 2000 as called for in the Act if funding, now about $365 million per year, were increased to the $1 billion range over the next few years (see Table I). We have also suggested that there may be an economic incentive for the private sector to become in accelerating fusion development on account of the greater stability of energy production costs from fusion. Namely, whereas fossil fuel prices will surely escalate in the course of time, fusion fuel will always be abundantly available at low cost; and fusion technology poses less future risk to the public and the investor compared to conventional nuclear power. In short, once a fusion plant is built, the cost of generating electricity mainly the amortization of the plant capital cost - would be relatively fixed for the life of the plant. In Sec. V, we found that the projected capital cost of fusion plants ($2000 to $4000 per KW/sub e/) would probably be acceptable if fusion plants were available today

Low energy incomplete fusion and its relevance to the synthesis of super heavy elements

Directory of Open Access Journals (Sweden)

Yadav Abhishek

2015-01-01

Full Text Available To study the presence of incomplete fusion at energies around the Coulomb-barrier and to understand its dependence on various entrance-channel parameters, the incomplete fusion fractions have been deduced (i from excitation function measurements for 18O,13,12C+159Tb, and (ii from forward recoil range measurements for 12C+159Tb systems, at low energies (<7MeV/A. The data have been analyzed within the framework of compound nucleus decay, which suggests the production of xn/pxn-channels via complete fusion, as these are found to be well reproduced by PACE4 predictions, while, a significant enhancement in the excitation functions of α-emitting channels has been observed over the theoretical ones, which has been attributed due to the incomplete fusion processes. Further, the incomplete fusion events observed in case of forward recoil ranges have been explained on the basis of the breakup fusion model, where these events may be attributed to the fusion of 8Be and/or 4He from 12C projectile to the target nucleus. For better insight into the underlying dynamics, the deduced fractions of incomplete fusion have been compared with other nearby systems as a function of various entrance channel parameters. The incomplete fusion has been found to be sensitive to the projectile’s energy and alpha-Q-value of the projectile.

Thermonuclear fusion

International Nuclear Information System (INIS)

Weisse, J.

2000-01-01

This document takes stock of the two ways of thermonuclear fusion research explored today: magnetic confinement fusion and inertial confinement fusion. The basic physical principles are recalled first: fundamental nuclear reactions, high temperatures, elementary properties of plasmas, ignition criterion, magnetic confinement (charged particle in a uniform magnetic field, confinement and Tokamak principle, heating of magnetized plasmas (ohmic, neutral particles, high frequency waves, other heating means), results obtained so far (scale laws and extrapolation of performances, tritium experiments, ITER project), inertial fusion (hot spot ignition, instabilities, results (Centurion-Halite program, laser experiments). The second part presents the fusion reactor and its associated technologies: principle (tritium production, heat source, neutron protection, tritium generation, materials), magnetic fusion (superconducting magnets, divertor (role, principle, realization), inertial fusion (energy vector, laser adaptation, particle beams, reaction chamber, stresses, chamber concepts (dry and wet walls, liquid walls), targets (fabrication, injection and pointing)). The third chapter concerns the socio-economic aspects of thermonuclear fusion: safety (normal operation and accidents, wastes), costs (costs structure and elementary comparison, ecological impact and external costs). (J.S.)

The contribution of fusion to sustainable development

International Nuclear Information System (INIS)

Ward, D.J.

2007-01-01

The world demand for energy is projected to more than double over the next 50 years, indeed this will be essential to bring much of the world out of poverty. At the same time there is increasing pressure to substantially reduce atmospheric pollution, most notably of carbon dioxide. Together, these conflicting goals drive a need to produce enormous amounts of non-carbon energy supply, much greater than our total present energy supply. This presents a huge challenge. As one of very few options for large-scale, non-carbon future supply of energy, fusion has the potential to make an important contribution to sustained energy supplies. Fusion's advantages of large fuel reserves, low atmospheric emissions and high levels of safety make it an important consideration in future energy strategies. Conceptual designs of fusion power plants have been optimised against safety and environmental criteria; the results are described here and the outcomes compared with other energy sources. To make a contribution to sustainable development, fusion must be economically viable in a future energy market. The calculated costs of electricity from fusion show that, particularly in an energy market where environmental constraints are playing an increasing role, fusion can make an important contribution

Nuclear fusion induced by x rays in a crystal

Science.gov (United States)

Belyaev, V. B.; Miller, M. B.; Otto, J.; Rakityansky, S. A.

2016-03-01

The nuclei that constitute a crystalline lattice oscillate relative to each other with a very low energy that is not sufficient to penetrate through the Coulomb barriers separating them. An additional energy, which is needed to tunnel through the barrier and fuse, can be supplied by external electromagnetic waves (x rays or synchrotron radiation). Exposing the solid compound LiD (lithium deuteride) to x rays for the duration of 111 h, we detect 88 events of nuclear fusion d +6Li→8Be* . Our theoretical estimate agrees with what we observed. One possible application of the phenomenon we found is in measurements of the rates of various nuclear reactions (not necessarily fusion) at extremely low energies inaccessible in accelerator experiments.

Fusion neutronics

CERN Document Server

Wu, Yican

2017-01-01

This book provides a systematic and comprehensive introduction to fusion neutronics, covering all key topics from the fundamental theories and methodologies, as well as a wide range of fusion system designs and experiments. It is the first-ever book focusing on the subject of fusion neutronics research. Compared with other nuclear devices such as fission reactors and accelerators, fusion systems are normally characterized by their complex geometry and nuclear physics, which entail new challenges for neutronics such as complicated modeling, deep penetration, low simulation efficiency, multi-physics coupling, etc. The book focuses on the neutronics characteristics of fusion systems and introduces a series of theories and methodologies that were developed to address the challenges of fusion neutronics, and which have since been widely applied all over the world. Further, it introduces readers to neutronics design’s unique principles and procedures, experimental methodologies and technologies for fusion systems...

Computer applications in controlled fusion research

International Nuclear Information System (INIS)

Killeen, J.

1975-02-01

The role of Nuclear Engineering Education in the application of computers to controlled fusion research can be a very important one. In the near future the use of computers in the numerical modelling of fusion systems should increase substantially. A recent study group has identified five categories of computational models to study the physics of magnetically confined plasmas. A comparable number of types of models for engineering studies are called for. The development and application of computer codes to implement these models is a vital step in reaching the goal of fusion power. In order to meet the needs of the fusion program the National CTR Computer Center has been established at the Lawrence Livermore Laboratory. A large central computing facility is linked to smaller computing centers at each of the major CTR laboratories by a communications network. The crucial element that is needed for success is trained personnel. The number of people with knowledge of plasma science and engineering that are trained in numerical methods and computer science is quite small, and must be increased substantially in the next few years. Nuclear Engineering departments should encourage students to enter this field and provide the necessary courses and research programs in fusion computing. (U.S.)

Fusion probability and survivability in estimates of heaviest nuclei production

Directory of Open Access Journals (Sweden)

Sagaidak Roman N.

2012-02-01

Full Text Available Production of the heavy and heaviest nuclei (from Po to the region of superheavy elements close to Z=114 and N=184 in fusion-evaporation reactions induced by heavy ions has been considered in a systematic way within the framework of the barrier-passing model coupled with the statistical model (SM of de-excitation of a compound nucleus (CN. Excitation functions for fission and evaporation residues (ER measured in very asymmetric combinations can be described rather well. One can scale and fix macroscopic (liquid-drop fission barriers for nuclei involved in the calculation of survivability with SM. In less asymmetric combinations, effects of fusion suppression caused by quasi-fission (QF are starting to appear in the entrance channel of reactions. QF effects could be semi-empirically taken into account using fusion probabilities deduced as the ratio of measured ER cross sections to the ones obtained in the assumption of absence of the fusion suppression in corresponding reactions. SM parameters (fission barriers obtained at the analysis of a very asymmetric combination leading to the production of (nearly the same CN should be used for this evaluation.

Public Relations on Fusion in Europe

Science.gov (United States)

Ongena, J.; van Oost, G.; Paris, P. J.

2000-10-01

A summary will be presented of PR efforts on fusion energy research in Europe. A 3-D movie of a fusion research experimental reactor has been realized at the start of this year. It has been made entirely on virtual animation basis. Two versions exists, a short version of 3 min., as a video clip, and a longer version of nearly 8 min. Both could be viewed in 3D, using special projections and passive glasses or in normal VHS video projections. A new CD-ROM for individual and classroom use will be presented, discussing (i) the different energy forms, (ii) general principles of fusion, (iii) current research efforts and (iv) future prospects of fusion. This CD-ROM is now produced in English, German, French, Spanish, Italian and Portuguese Several new brochures and leaflets intended to increase the public awareness on fusion in Europe will be on display.

Breeder control fusion reactor. Topical interview

Energy Technology Data Exchange (ETDEWEB)

Schlueter, A [Max-Planck-Institut fuer Plasmaphysik, Garching/Muenchen (Germany, F.R.)

1977-09-01

The energy sources of the future are extremely controversial. The consumption of fossil fuel shall decrease during the next decades, because exhaustion of the resources, pollution, increase of CO/sub 2/ in the atmosphere and other reasons. But at present the question it not yet settled which alternative energy system should replace the fossil fuel. First of all nuclear energy in the form of fission reactions seems to come into operation to a larger extent. The next step may be the controlled thermonuclear fusion reaction. Furthermore, a comparison between fusion and fission is given which shows that fusion would bring about less risks than the breeders. An advantage of the fusion reactor would be the fact that the fuel cycle is closed. Unfortunately, the physical questions are not as yet satisfactorily clarified so that one cannot be sure whether a fusion reactor can really be built.

Optimization of nonthermal fusion power consistent with energy channeling

International Nuclear Information System (INIS)

Snyder, P.B.; Herrmann, M.C.; Fisch, N.J.

1995-02-01

If the energy of charged fusion products can be diverted directly to fuel ions, non-Maxwellian fuel ion distributions and temperature differences between species will result. To determine the importance of these nonthermal effects, the fusion power density is optimized at constant-β for nonthermal distributions that are self-consistently maintained by channeling of energy from charged fusion products. For D-T and D- 3 He reactors, with 75% of charged fusion product power diverted to fuel ions, temperature differences between electrons and ions increase the reactivity by 40-70%, while non- Maxwellian fuel ion distributions and temperature differences between ionic species increase the reactivity by an additional 3-15%

Muon-catalyzed fusion: A new direction in fusion research

International Nuclear Information System (INIS)

Jones, S.E.

1986-01-01

In four years of intensive research, muon-catalyzed fusion has been raised from the level of a scientific curiosity to a potential means of achieving clean fusion energy. This novel approach to fusion is based on the fact that a sub-atomic particle known as a ''muon'' can induce numerous energy-releasing fusion reactions without the need for high temperatures or plasmas. Thus, the muon serves as a catalyst to facilitate production for fusion energy. The success of the research effort stems from the recent discovery of resonances in the reaction cycle which make the muon-induced fusion process extremely efficient. Prior estimates were pessimistic in that only one fusion per muon was expected. In that case energy balance would be impossible since energy must be invested to generate the muons. However, recent work has gone approximately half-way to energy balance and further improvements are being worked on. There has been little time to assess the full implications of these discoveries. However, various ways to use muon-catalyzed fusion for electrical power production are now being explored

Muon-catalyzed fusion: a new direction in fusion research

International Nuclear Information System (INIS)

Jones, S.E.

1986-01-01

In four years of intensive research, muon-catalyzed fusion has been raised from the level of a scientific curiosity to a potential means of achieving clean fusion energy. This novel approach to fusion is based on the fact that a sub-atomic particle known as a ''muon'' can induce numerous energy-releasing fusion reactions without the need for high temperatures or plasmas. Thus, the muon serves as a catalyst to facilitate production for fusion energy. The success of the research effort stems from the recent discovery of resonances in the reaction cycle which make the muon-induced fusion process extremely efficient. Prior estimates were pessimistic in that only one fusion per muon was expected. In that case energy balance would be impossible since energy must be invested to generate the muons. However, recent work has gone approximately half-way to energy balance and further improvements are being worked on. There has been little time to assess the full implications of these discoveries. However, various ways to use muon-catalyzed fusion for electrical power production are now being explored

Fusion breeder

International Nuclear Information System (INIS)

Moir, R.W.

1982-01-01

The fusion breeder is a fusion reactor designed with special blankets to maximize the transmutation by 14 MeV neutrons of uranium-238 to plutonium or thorium to uranium-233 for use as a fuel for fission reactors. Breeding fissile fuels has not been a goal of the US fusion energy program. This paper suggests it is time for a policy change to make the fusion breeder a goal of the US fusion program and the US nuclear energy program. The purpose of this paper is to suggest this policy change be made and tell why it should be made, and to outline specific research and development goals so that the fusion breeder will be developed in time to meet fissile fuel needs

Research into thermonuclear fusion

International Nuclear Information System (INIS)

Schumacher, U.

1989-01-01

The experimental and theoretical studies carried out in close international cooperation in the field of thermonuclear fusion by magnetic plasma confinement have achieved such progress towards higher plasma temperatures and densities, longer confinement times and, thus, increased fusion product, that emphasis now begins to be shifted from problems of physics to those of technology as a next major step is being prepared towards a large international project (ITER) to achieve thermonuclear burning. The generation and maintenance of a burning fusion plasma in an experimental physics phase will be followed by a phase of technical materials studies at high fluxes of fusion neutrons. These goals have been pursued since 1983 by an international study group at Garching working on the design of a Next European Torus (NET). Since May 1988, an international study group comprising ten experts each from the USSR, USA, Japan, and the European Community has begun to work on a design draft of ITER (International Thermonuclear Experimental Reactor) in Garching under the auspices of IAEA. (orig.) [de

Computer applications in controlled fusion research

International Nuclear Information System (INIS)

Killeen, J.

1975-01-01

The application of computers to controlled thermonuclear research (CTR) is essential. In the near future the use of computers in the numerical modeling of fusion systems should increase substantially. A recent panel has identified five categories of computational models to study the physics of magnetically confined plasmas. A comparable number of types of models for engineering studies is called for. The development and application of computer codes to implement these models is a vital step in reaching the goal of fusion power. To meet the needs of the fusion program the National CTR Computer Center has been established at the Lawrence Livermore Laboratory. A large central computing facility is linked to smaller computing centers at each of the major CTR Laboratories by a communication network. The crucial element needed for success is trained personnel. The number of people with knowledge of plasma science and engineering trained in numerical methods and computer science must be increased substantially in the next few years. Nuclear engineering departments should encourage students to enter this field and provide the necessary courses and research programs in fusion computing

Visualization of graphical information fusion results

Science.gov (United States)

Blasch, Erik; Levchuk, Georgiy; Staskevich, Gennady; Burke, Dustin; Aved, Alex

2014-06-01

Graphical fusion methods are popular to describe distributed sensor applications such as target tracking and pattern recognition. Additional graphical methods include network analysis for social, communications, and sensor management. With the growing availability of various data modalities, graphical fusion methods are widely used to combine data from multiple sensors and modalities. To better understand the usefulness of graph fusion approaches, we address visualization to increase user comprehension of multi-modal data. The paper demonstrates a use case that combines graphs from text reports and target tracks to associate events and activities of interest visualization for testing Measures of Performance (MOP) and Measures of Effectiveness (MOE). The analysis includes the presentation of the separate graphs and then graph-fusion visualization for linking network graphs for tracking and classification.

Achievement of solid-state plasma fusion ('Cold-Fusion')

International Nuclear Information System (INIS)

Arata, Yoshiaki; Zhang, Yue-Chang

1995-01-01

Using a 'QMS' (Quadrupole Mass Spectrometer), the authors detected a significantly large amount (10 20 -10 21 [cm -3 ]) of helium ( 2 4 He), which was concluded to have been produced by a deuterium nuclear reaction within a host solid. These results were found to be fully repeatable and supported the authors' proposition that solid state plasma fusion ('Cold Fusion') can be generated in energetic deuterium Strongly Coupled Plasma ('SC-plasma'). This fusion reaction is thought to be sustained by localized 'Latticequake' in a solid-state media with the deuterium density equivalent to that of the host solid. While exploring this basic proposition, the characteristic differences when compared with ultra high temperature-state plasma fusion ('Hot Fusion') are clarified. In general, the most essential reaction product in both types of the deuterium plasma fusion is considered to be helium, irrespective of the 'well-known and/or unknown reactions', which is stored within the solid-state medium in abundance as a 'Residual Product', but which generally can not enter into nor be released from host-solid at a room temperature. Even measuring instruments with relatively poor sensitivity should be able to easily detect such residual helium. An absence of residual helium means that no nuclear fusion reaction has occurred, whereas its presence provides crucial evidence that nuclear fusion has, in fact, occurred in the solid. (author)

Efforts in Public Relations on Fusion in Europe

Science.gov (United States)

Ongena, J.; van Oost, G.

2001-10-01

An overview will be given of different published materials currently in use in Europe for public relations on fusion. We will also present a CD-ROM for individual and classroom use, containing (i) a general background on different energy forms, (ii) general principles of fusion, (iii) current research efforts and (iv) future prospects of fusion. This CD-ROM is currently in English, German, French, Spanish, Portuguese and Italian. Fusion posters developed in collaboration with CPEP in Dutch, French, German, Italian, Spanish and Portuguese will be shown. Several new brochures and leaflets intended to increase the public awareness on fusion in Europe will be on display.

Fusion Implementation

International Nuclear Information System (INIS)

Schmidt, J.A.

2002-01-01

If a fusion DEMO reactor can be brought into operation during the first half of this century, fusion power production can have a significant impact on carbon dioxide production during the latter half of the century. An assessment of fusion implementation scenarios shows that the resource demands and waste production associated with these scenarios are manageable factors. If fusion is implemented during the latter half of this century it will be one element of a portfolio of (hopefully) carbon dioxide limiting sources of electrical power. It is time to assess the regional implications of fusion power implementation. An important attribute of fusion power is the wide range of possible regions of the country, or countries in the world, where power plants can be located. Unlike most renewable energy options, fusion energy will function within a local distribution system and not require costly, and difficult, long distance transmission systems. For example, the East Coast of the United States is a prime candidate for fusion power deployment by virtue of its distance from renewable energy sources. As fossil fuels become less and less available as an energy option, the transmission of energy across bodies of water will become very expensive. On a global scale, fusion power will be particularly attractive for regions separated from sources of renewable energy by oceans

Fusion: introduction

International Nuclear Information System (INIS)

Decreton, M.

2006-01-01

The article gives an overview and introduction to the activities of SCK-CEN's research programme on fusion. The decision to construct the ITER international nuclear fusion experiment in Cadarache is highlighted. A summary of the Belgian contributions to fusion research is given with particular emphasis on studies of radiation effects on diagnostics systems, radiation effects on remote handling sensing systems, fusion waste management and socio-economic studies

Status report on fusion research

International Nuclear Information System (INIS)

Burkhart, Werner

2005-01-01

At the beginning of the twenty-first century mankind is faced with the serious problem of meeting the energy demands of a rapidly industrializing population around the globe. This, against the backdrop of fast diminishing fossil fuel resources (which have been the main source of energy of the last century) and the increasing realization that the use of fossil fuels has started to adversely affect our environment, has greatly intensified the quest for alternative energy sources. In this quest, fusion has the potential to play a very important role and we are today at the threshold of realizing net energy production from controlled fusion experiments. Fusion is, today, one of the most promising of all alternative energy sources because of the vast reserves of fuel, potentially lasting several thousands of years and the possibility of a relatively 'clean' form of energy, as required for use in concentrated urban industrial settings, with minimal long term environmental implications. The last decade and a half has seen unprecedented advances in controlled fusion experiments with the discovery of new regimes of operations in experiments, production of 16 MW of fusion power and operations close to and above the so-called 'break-even' conditions. A great deal of research has also been carried out in analysing various socio-economic aspects of fusion energy. This paper briefly reviews the various aspects and achievements of fusion research all over the world during this period

Study of the effect of 11Be halo on the sub-coulombian fusion

International Nuclear Information System (INIS)

Felou Youmbi, V.

1996-01-01

Fission cross sections of 9,11 Be + 238 U systems are measured in the energy range of the coulomb barrier. These measures allow the study of neutron halo effect on sub coulombian fusion. 9,11 Be beams are obtained by fragmentation at the GANIL facilities. The fusion between incident particle and the target nucleus leads to a compound nucleus which disappears by fission. The FUSION detector is used to detect the fission fragments by coincidence. We present some calculations of potential barriers by using Wong formula. The nucleus-nucleus interaction is simulated by a double convolution between the nucleus density and the effective M3Y interaction. In a more realistic framework ECIS94 code calculates the fusion cross section by using a coupling formalism. Theoretical values and experimental results are compared. We get a good agreement for 9 Be + 238 U system and an unusual behaviour appears for 11 Be + 238 U system

The role of chain carriers in fusion reaction kinetics

International Nuclear Information System (INIS)

Harms, A.A.; Krenciglowa, E.M.

1980-01-01

The role of chain carriers as contributors to multiplicative closed cycles in advanced fusion fuels is examined. Emphasis is placed on rate processes which can be used to characterize critical/supercritical/subcritical tendencies of arbitrary closed fusion cycles. Temporal trajectories for the chain carriers which describe both increasing and decreasing multiplicative processes have been found to exist and identified according to their fusion fuel cycle characteristics. Practical criteria to ensure the attainment of steady-state fusion reaction processes have been formulated in terms of fusion reaction rate relationships. (author)

Increase in volatilization of organic compounds using air sparging through addition in alcohol in a soil-water system.

Science.gov (United States)

Chao, Huan-Ping; Hsieh, Lin-Han Chiang; Tran, Hai Nguyen

2018-02-15

This study developed a novel method to promote the remediation efficiency of air sparging. According to the enhanced-volatilization theory presented in this study, selected alcohols added to groundwater can highly enhance the volatilization amounts of organic compounds with high Henry's law constants. In this study, the target organic compounds consisted of n-hexane, n-heptane, benzene, toluene, 1,1,2-trichloroethane, and tetrachloroethene. n-pentanol, n-hexanol, and n-heptanol were used to examine the changes in the volatilization amounts of organic compounds in the given period. Two types of soils with high and low organic matter were applied to evaluate the transport of organic compounds in the soil-water system. The volatilization amounts of the organic compounds increased with increasing alcohol concentrations. The volatilization amounts of the test organic compounds exhibited a decreasing order: n-heptanol>n-hexanol>n-pentanol. When 10mg/L n-heptanol was added to the system, the maximum volatilization enhancement rate was 18-fold higher than that in distilled water. Samples of soil with high organic matter might reduce the volatilization amounts by a factor of 5-10. In the present study, the optimal removal efficiency for aromatic compounds was approximately 98%. Copyright © 2017 Elsevier B.V. All rights reserved.

Fusion--fission hybrid concepts for laser-induced fusion

International Nuclear Information System (INIS)

Maniscalco, J.

1976-01-01

Fusion-fission hybrid concepts are viewed as subcritical fission reactors driven and controlled by high-energy neutrons from a laser-induced fusion reactor. Blanket designs encompassing a substantial portion of the spectrum of different fission reactor technologies are analyzed and compared by calculating their fissile-breeding and fusion-energy-multiplying characteristics. With a large number of different fission technologies to choose from, it is essential to identify more promising hybrid concepts that can then be subjected to in-depth studies that treat the engineering safety, and economic requirements as well as the neutronic aspects. In the course of neutronically analyzing and comparing several fission blanket concepts, this work has demonstrated that fusion-fission hybrids can be designed to meet a broad spectrum of fissile-breeding and fusion-energy-multiplying requirements. The neutronic results should prove to be extremely useful in formulating the technical scope of future studies concerned with evaluating the technical and economic feasibility of hybrid concepts for laser-induced fusion

Recent fusion research in the National Institute for Fusion Science

International Nuclear Information System (INIS)

Komori, Akio; Sakakibara, Satoru; Sagara, Akio; Horiuchi, Ritoku; Yamada, Hiroshi; Takeiri, Yasuhiko

2011-01-01

The National Institute for Fusion Science (NIFS), which was established in 1989, promotes academic approaches toward the exploration of fusion science for steady-state helical reactor and realizes the establishment of a comprehensive understanding of toroidal plasmas as an inter-university research organization and a key center of worldwide fusion research. The Large Helical Device (LHD) Project, the Numerical Simulation Science Project, and the Fusion Engineering Project are organized for early realization of net current free fusion reactor, and their recent activities are described in this paper. The LHD has been producing high-performance plasmas comparable to those of large tokamaks, and several new findings with regard to plasma physics have been obtained. The numerical simulation science project contributes understanding and systemization of the physical mechanisms of plasma confinement in fusion plasmas and explores complexity science of a plasma for realization of the numerical test reactor. In the fusion engineering project, the design of the helical fusion reactor has progressed based on the development of superconducting coils, the blanket, fusion materials and tritium handling. (author)

Measurement of 18O + 10B fusion cross section and construction of a position sensitive ionization chamber

International Nuclear Information System (INIS)

Added, N.

1987-01-01

The 18 O + 10 B fusion reaction has been investigated within the bombarding energy range of 29,0 MeV lab 0 lab 0 angular range. For this purpose, a high resolution position sensitive ionization chamber has been developed and constructed. Experimental results compared to model predictions and experimental systematics found in the literature allows to reject compound nucleus limitation to the fusion cross section up to energies as high as five times the coulomb barrier. Statistical model fits to the residues elementary distributions reveal a quite difuse partial fusion cross section in the angular momentum space. Systematic analysis of fusion barrier height (V B ) and radius (R B ) for neighbouring nuclei point out the importance of the nuclear matter difuseness in the competition between the fusion and quasi-direct process. Calculations within this framework were performed. (author) [pt

Viral membrane fusion

International Nuclear Information System (INIS)

Harrison, Stephen C.

2015-01-01

Membrane fusion is an essential step when enveloped viruses enter cells. Lipid bilayer fusion requires catalysis to overcome a high kinetic barrier; viral fusion proteins are the agents that fulfill this catalytic function. Despite a variety of molecular architectures, these proteins facilitate fusion by essentially the same generic mechanism. Stimulated by a signal associated with arrival at the cell to be infected (e.g., receptor or co-receptor binding, proton binding in an endosome), they undergo a series of conformational changes. A hydrophobic segment (a “fusion loop” or “fusion peptide”) engages the target-cell membrane and collapse of the bridging intermediate thus formed draws the two membranes (virus and cell) together. We know of three structural classes for viral fusion proteins. Structures for both pre- and postfusion conformations of illustrate the beginning and end points of a process that can be probed by single-virion measurements of fusion kinetics. - Highlights: • Viral fusion proteins overcome the high energy barrier to lipid bilayer merger. • Different molecular structures but the same catalytic mechanism. • Review describes properties of three known fusion-protein structural classes. • Single-virion fusion experiments elucidate mechanism

Viral membrane fusion

Energy Technology Data Exchange (ETDEWEB)

Harrison, Stephen C., E-mail: harrison@crystal.harvard.edu

2015-05-15

Membrane fusion is an essential step when enveloped viruses enter cells. Lipid bilayer fusion requires catalysis to overcome a high kinetic barrier; viral fusion proteins are the agents that fulfill this catalytic function. Despite a variety of molecular architectures, these proteins facilitate fusion by essentially the same generic mechanism. Stimulated by a signal associated with arrival at the cell to be infected (e.g., receptor or co-receptor binding, proton binding in an endosome), they undergo a series of conformational changes. A hydrophobic segment (a “fusion loop” or “fusion peptide”) engages the target-cell membrane and collapse of the bridging intermediate thus formed draws the two membranes (virus and cell) together. We know of three structural classes for viral fusion proteins. Structures for both pre- and postfusion conformations of illustrate the beginning and end points of a process that can be probed by single-virion measurements of fusion kinetics. - Highlights: • Viral fusion proteins overcome the high energy barrier to lipid bilayer merger. • Different molecular structures but the same catalytic mechanism. • Review describes properties of three known fusion-protein structural classes. • Single-virion fusion experiments elucidate mechanism.

Phosphomimetic mutation of cysteine string protein-α increases the rate of regulated exocytosis by modulating fusion pore dynamics in PC12 cells.

Directory of Open Access Journals (Sweden)

Ning Chiang

Full Text Available BACKGROUND: Cysteine string protein-α (CSPα is a chaperone to ensure protein folding. Loss of CSPα function associates with many neurological diseases. However, its function in modulating regulated exocytosis remains elusive. Although cspα-knockouts exhibit impaired synaptic transmission, overexpression of CSPα in neuroendocrine cells inhibits secretion. These seemingly conflicting results lead to a hypothesis that CSPα may undergo a modification that switches its function in regulating neurotransmitter and hormone secretion. Previous studies implied that CSPα undergoes phosphorylation at Ser10 that may influence exocytosis by altering fusion pore dynamics. However, direct evidence is missing up to date. METHODOLOGY/PRINCIPAL FINDINGS: Using amperometry, we investigated how phosphorylation at Ser10 of CSPα (CSPα-Ser10 modulates regulated exocytosis and if this modulation involves regulating a specific kinetic step of fusion pore dynamics. The real-time exocytosis of single vesicles was detected in PC12 cells overexpressing control vector, wild-type CSPα (WT, the CSPα phosphodeficient mutant (S10A, or the CSPα phosphomimetic mutants (S10D and S10E. The shapes of amperometric signals were used to distinguish the full-fusion events (i.e., prespike feet followed by spikes and the kiss-and-run events (i.e., square-shaped flickers. We found that the secretion rate was significantly increased in cells overexpressing S10D or S10E compared to WT or S10A. Further analysis showed that overexpression of S10D or S10E prolonged fusion pore lifetime compared to WT or S10A. The fraction of kiss-and-run events was significantly lower but the frequency of full-fusion events was higher in cells overexpressing S10D or S10E compared to WT or S10A. Advanced kinetic analysis suggests that overexpression of S10D or S10E may stabilize open fusion pores mainly by inhibiting them from closing. CONCLUSIONS/SIGNIFICANCE: CSPα may modulate fusion pore dynamics

Hybrid Fusion for Biometrics: Combining Score-level and Decision-level Fusion

NARCIS (Netherlands)

Tao, Q.; Veldhuis, Raymond N.J.

2008-01-01

A general framework of fusion at decision level, which works on ROCs instead of matching scores, is investigated. Under this framework, we further propose a hybrid fusion method, which combines the score-level and decision-level fusions, taking advantage of both fusion modes. The hybrid fusion

A fluorescence-based rapid screening assay for cytotoxic compounds

International Nuclear Information System (INIS)

Montoya, Jessica; Varela-Ramirez, Armando; Estrada, Abril; Martinez, Luis E.; Garza, Kristine; Aguilera, Renato J.

2004-01-01

A simple fluorescence-based assay was developed for the rapid screening of potential cytotoxic compounds generated by combinatorial chemistry. The assay is based on detection of nuclear green fluorescent protein (GFP) staining of a human cervical cancer cell line (HeLa) carrying an integrated histone H2B-GFP fusion gene. Addition of a cytotoxic compound to the HeLa-GFP cells results in the eventual degradation of DNA and loss of the GFP nuclear fluorescence. Using this assay, we screened 11 distinct quinone derivatives and found that several of these compounds were cytotoxic. These compounds are structurally related to plumbagin an apoptosis-inducing naphthoquinone isolated from Black Walnut. In order to determine the mechanism by which cell death was induced, we performed additional experiments with the most cytotoxic quinones. These compounds were found to induce morphological changes (blebbing and nuclear condensation) consistent with induction of apoptosis. Additional tests revealed that the cytotoxic compounds induce both necrotic and apoptotic modes of death

A schedule for fusion research development and international collaboration

International Nuclear Information System (INIS)

Kakihana, H.

1983-01-01

In order to reach their goal of commercial fusion power reactors, development must proceed in a series of basic stages. Each step is expected to incur an increased level of cost. The cost-sharing benefits of international collaboration will become increasingly important and attractive with each successive step preceding commercialization. Outstanding examples of implementation of international collaboration in fusion include the JET project and the INTOR workshop which lend encouragement for the prospects for international collaboration in fusion in the future. (author)

Lateral Transpsoas Fusion: Indications and Outcomes

Directory of Open Access Journals (Sweden)

Vishal C. Patel

2012-01-01

Full Text Available Spinal fusion historically has been used extensively, and, recently, the lateral transpsoas approach to the thoracic and lumbar spine has become an increasingly common method to achieve fusion. Recent literature on this approach has elucidated its advantage over more traditional anterior and posterior approaches, which include a smaller tissue dissection, potentially lower blood loss, no need for an access surgeon, and a shorter hospital stay. Indications for the procedure have now expanded to include degenerative disc disease, spinal stenosis, degenerative scoliosis, nonunion, trauma, infection, and low-grade spondylolisthesis. Lateral interbody fusion has a similar if not lower rate of complications compared to traditional anterior and posterior approaches to interbody fusion. However, lateral interbody fusion has unique complications that include transient neurologic symptoms, motor deficits, and neural injuries that range from 1 to 60% in the literature. Additional studies are required to further evaluate and monitor the short- and long-term safety, efficacy, outcomes, and complications of lateral transpsoas procedures.

The need and prospects for improved fusion reactors

International Nuclear Information System (INIS)

Krakowski, R.A.; Hagenson, R.L.; Miller, R.L.

1986-01-01

Conceptual fusion reactor studies over the past 10-15 yr have projected systems that may be too large, complex, and costly to be of commercial interest. One main direction for improved fusion reactors points toward smaller, higher-power-density approaches. First-order economic issues (i.e., unit direct cost and cost of electricity) are used to support the need for more compact fusion reactors. The results of a number of recent conceptual designs of reversed-field pinch, spheromak, and tokamak fusion reactors are summarized as examples of more compact approaches. While a focus has been placed on increasing the fusion-power-core mass power density beyond the minimum economic threshold of 100-200 kWe/tonne, other means by which the overall attractiveness of fusion as a long-term energy source are also addressed

Peaceful fusion

Energy Technology Data Exchange (ETDEWEB)

Englert, Matthias [IANUS, TU Darmstadt (Germany)

2014-07-01

Like other intense neutron sources fusion reactors have in principle a potential to be used for military purposes. Although the use of fissile material is usually not considered when thinking of fusion reactors (except in fusion-fission hybrid concepts) quantitative estimates about the possible production potential of future commercial fusion reactor concepts show that significant amounts of weapon grade fissile materials could be produced even with very limited amounts of source materials. In this talk detailed burnup calculations with VESTA and MCMATH using an MCNP model of the PPCS-A will be presented. We compare different irradiation positions and the isotopic vectors of the plutonium bred in different blankets of the reactor wall with the liquid lead-lithium alloy replaced by uranium. The technical, regulatory and policy challenges to manage the proliferation risks of fusion power will be addressed as well. Some of these challenges would benefit if addressed at an early stage of the research and development process. Hence, research on fusion reactor safeguards should start as early as possible and accompany the current research on experimental fusion reactors.

The role of fusion as a future power source

International Nuclear Information System (INIS)

Kintner, E.E.; Hirsch, R.L.

1977-01-01

Nations of western Europe, Japan, the Soviet Union, and the United States are working together to demonstrate the practicality of fusion power early in the 21st century. Many difficult engineering problems make fusion development one of the most formidable scientific and technological challenges ever attempted. However, the outlook is promising for achieving an inexhaustible energy source that is safe, economic, and with acceptable environmental effects. The United States magnetic fusion power development program aims at producing fusion energy experimentally in the early 1980's and demonstrating power production on a commercial scale before 2000. This prognosis reflects the confidence gained in scientific successes of the late 1960's through the present. However, many physics problems remain to be solved and many complex engineering problems without obvious solutions await attention. In response to experimental successes and the perceived importance of the fusion energy alternative, the United States effort has grown rapidly. Scientific investigations of plasma physics continue while planned engineering studies lead toward the practical goal of a commercial technology that will take a prominent place among available energy sources of the next century. Development of laser and electron beam fusion proceeds. Alternative fusion devices are investigated for their potential feasibility while the tokamak configuration is used for principal experimental devices. A national program plan and budget coordinates the efforts of federal laboratories, universities and industry. The utilities industry conducts an independent program which is increasingly coordinated with government-sponsored activity. Fusion energy programs of several nations benefit one another and should cooperate more closely in specific problem areas. Achievement of practical fusion power could be advanced through more effective mutually supporting fusion development programs. The economic and technical

Material synergism fusion-fission

International Nuclear Information System (INIS)

Sankara Rao, K.B.; Raj, B.; Cook, I.; Kohyama, A.; Dudarev, S.

2007-01-01

In fission and fusion reactors the common features such as operating temperatures and neutron exposures will have the greatest impact on materials performance and component lifetimes. Developing fast neutron irradiation resisting materials is a common issue for both fission and fusion reactors. The high neutron flux levels in both these systems lead to unique materials problems like void swelling, irradiation creep and helium embitterment. Both fission and fusion rely on ferritic-martensitic steels based on 9%Cr compositions for achieving the highest swelling resistance but their creep strength sharply decreases above ∝ 823K. The use of oxide dispersion strengthened (ODS) alloys is envisaged to increase the operating temperature of blanket systems in the fusion reactors and fuel clad tubes in fast breeder reactors. In view of high operating temperatures, cyclic and steady load conditions and the long service life, properties like creep, low cycle fatigue,fracture toughness and creepfatigue interaction are major considerations in the selection of structural materials and design of components for fission and fusion reactors. Currently, materials selection for fusion systems has to be based upon incomplete experimental database on mechanical properties. The usage of fairly well developed databases, in fission programmes on similar materials, is of great help in the initial design of fusion reactor components. Significant opportunities exist for sharing information on technology of irradiation testing, specimen miniaturization, advanced methods of property measurement, safe windows for metal forming, and development of common materials property data base system. Both fusion and fission programs are being directed to development of clean steels with very low trace and tramp elements, characterization of microstructure and phase stability under irradiation, assessment of irradiation creep and swelling behaviour, studies on compatibility with helium and developing

Report of the Fusion Energy Sciences Advisory Committee. Panel on Integrated Simulation and Optimization of Magnetic Fusion Systems

International Nuclear Information System (INIS)

Dahlburg, Jill; Corones, James; Batchelor, Donald; Bramley, Randall; Greenwald, Martin; Jardin, Stephen; Krasheninnikov, Sergei; Laub, Alan; Leboeuf, Jean-Noel; Lindl, John; Lokke, William; Rosenbluth, Marshall; Ross, David; Schnack, Dalton

2002-01-01

Fusion is potentially an inexhaustible energy source whose exploitation requires a basic understanding of high-temperature plasmas. The development of a science-based predictive capability for fusion-relevant plasmas is a challenge central to fusion energy science, in which numerical modeling has played a vital role for more than four decades. A combination of the very wide range in temporal and spatial scales, extreme anisotropy, the importance of geometric detail, and the requirement of causality which makes it impossible to parallelize over time, makes this problem one of the most challenging in computational physics. Sophisticated computational models are under development for many individual features of magnetically confined plasmas and increases in the scope and reliability of feasible simulations have been enabled by increased scientific understanding and improvements in computer technology. However, full predictive modeling of fusion plasmas will require qualitative improvements and innovations to enable cross coupling of a wider variety of physical processes and to allow solution over a larger range of space and time scales. The exponential growth of computer speed, coupled with the high cost of large-scale experimental facilities, makes an integrated fusion simulation initiative a timely and cost-effective opportunity. Worldwide progress in laboratory fusion experiments provides the basis for a recent FESAC recommendation to proceed with a burning plasma experiment (see FESAC Review of Burning Plasma Physics Report, September 2001). Such an experiment, at the frontier of the physics of complex systems, would be a huge step in establishing the potential of magnetic fusion energy to contribute to the world's energy security. An integrated simulation capability would dramatically enhance the utilization of such a facility and lead to optimization of toroidal fusion plasmas in general. This science-based predictive capability, which was cited in the

Report of the Fusion Energy Sciences Advisory Committee. Panel on Integrated Simulation and Optimization of Magnetic Fusion Systems

Energy Technology Data Exchange (ETDEWEB)

Dahlburg, Jill [General Atomics, San Diego, CA (United States); Corones, James [Krell Inst., Ames, IA (United States); Batchelor, Donald [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Bramley, Randall [Indiana Univ., Bloomington, IN (United States); Greenwald, Martin [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Jardin, Stephen [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Krasheninnikov, Sergei [Univ. of California, San Diego, CA (United States); Laub, Alan [Univ. of California, Davis, CA (United States); Leboeuf, Jean-Noel [Univ. of California, Los Angeles, CA (United States); Lindl, John [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Lokke, William [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rosenbluth, Marshall [Univ. of California, San Diego, CA (United States); Ross, David [Univ. of Texas, Austin, TX (United States); Schnack, Dalton [Science Applications International Corporation, Oak Ridge, TN (United States)

2002-11-01

Fusion is potentially an inexhaustible energy source whose exploitation requires a basic understanding of high-temperature plasmas. The development of a science-based predictive capability for fusion-relevant plasmas is a challenge central to fusion energy science, in which numerical modeling has played a vital role for more than four decades. A combination of the very wide range in temporal and spatial scales, extreme anisotropy, the importance of geometric detail, and the requirement of causality which makes it impossible to parallelize over time, makes this problem one of the most challenging in computational physics. Sophisticated computational models are under development for many individual features of magnetically confined plasmas and increases in the scope and reliability of feasible simulations have been enabled by increased scientific understanding and improvements in computer technology. However, full predictive modeling of fusion plasmas will require qualitative improvements and innovations to enable cross coupling of a wider variety of physical processes and to allow solution over a larger range of space and time scales. The exponential growth of computer speed, coupled with the high cost of large-scale experimental facilities, makes an integrated fusion simulation initiative a timely and cost-effective opportunity. Worldwide progress in laboratory fusion experiments provides the basis for a recent FESAC recommendation to proceed with a burning plasma experiment (see FESAC Review of Burning Plasma Physics Report, September 2001). Such an experiment, at the frontier of the physics of complex systems, would be a huge step in establishing the potential of magnetic fusion energy to contribute to the world’s energy security. An integrated simulation capability would dramatically enhance the utilization of such a facility and lead to optimization of toroidal fusion plasmas in general. This science-based predictive capability, which was cited in the FESAC

Pre-compound neutron evaporation in heavy ion fusion reactions

International Nuclear Information System (INIS)

Ajay Kumar; Singh, Hardev; Rajesh Kumar; Govil, I.M.; Golda, K.S.; Rakesh Kumar; Datta, S.K.; Yogi, B.K.; Viesti, G.

2007-01-01

In the present investigation, exclusive neutron spectra have been measured in coincidence with the observed γ-rays characteristic to the residual nuclei 53 Fe, 55 Fe and 56 Co. In this new experimental study, we have followed the strategy of forming the compound nucleus 58 Ni at the same excitation energy through two different entrance channels viz the mass symmetric reaction 31 P + 27 Al and the mass asymmetric reaction 12 C + 46 Ti

Hybrid testing of lumbar CHARITE discs versus fusions.

Science.gov (United States)

Panjabi, Manohar; Malcolmson, George; Teng, Edward; Tominaga, Yasuhiro; Henderson, Gweneth; Serhan, Hassan

2007-04-20

An in vitro human cadaveric biomechanical study. To quantify effects on operated and other levels, including adjacent levels, due to CHARITE disc implantations versus simulated fusions, using follower load and the new hybrid test method in flexion-extension and bilateral torsion. Spinal fusion has been associated with long-term accelerated degeneration at adjacent levels. As opposed to the fusion, artificial discs are designed to preserve motion and diminish the adjacent-level effects. Five fresh human cadaveric lumbar specimens (T12-S1) underwent multidirectional testing in flexion-extension and bilateral torsion with 400 N follower load. Intact specimen total ranges of motion were determined with +/-10 Nm unconstrained pure moments. The intact range of motion was used as input for the hybrid tests of 5 constructs: 1) CHARITE disc at L5-S1; 2) fusion at L5-S1; 3) CHARITE discs at L4-L5 and L5-S1; 4) CHARITE disc at L4-L5 and fusion at L5-S1; and 5) 2-level fusion at L4-L5-S1. Using repeated-measures single factor analysis of variance and Bonferroni statistical tests (P < 0.05), intervertebral motion redistribution of each construct was compared with the intact. In flexion-extension, 1-level CHARITE disc preserved motion at the operated and other levels, while 2-level CHARITE showed some amount of other-level effects. In contrast, 1- and 2-level fusions increased other-level motions (average, 21.0% and 61.9%, respectively). In torsion, both 1- and 2-level discs preserved motions at all levels. The 2-level simulated fusion increased motions at proximal levels (22.9%), while the 1-level fusion produced no significant changes. In general, CHARITE discs preserved operated- and other-level motions. Fusion simulations affected motion redistribution at other levels, including adjacent levels.

Cold fusion, Alchemist's dream

International Nuclear Information System (INIS)

Clayton, E.D.

1989-09-01

In this report the following topics relating to cold fusion are discussed: muon catalysed cold fusion; piezonuclear fusion; sundry explanations pertaining to cold fusion; cosmic ray muon catalysed cold fusion; vibrational mechanisms in excited states of D 2 molecules; barrier penetration probabilities within the hydrogenated metal lattice/piezonuclear fusion; branching ratios of D 2 fusion at low energies; fusion of deuterons into 4 He; secondary D+T fusion within the hydrogenated metal lattice; 3 He to 4 He ratio within the metal lattice; shock induced fusion; and anomalously high isotopic ratios of 3 He/ 4 He

Progress of nuclear fusion research and review on development of fusion reactors

International Nuclear Information System (INIS)

1976-01-01

Set up in October 1971, the ad hoc Committee on Survey of Nuclear Fusion Reactors has worked on overall fusion reactor aspects and definition of the future problems under four working groups of core, nuclear heat, materials and system. The presect volume is intended to provide reference materials in the field of fusion reactor engineering, prepared by members of the committee. Contents are broadly the following: concept of the nuclear fusion reactor, fusion core engineering, fusion reactor blanket engineering, fusion reactor materials engineering, and system problems in development of fusion reactors. (Mori, K.)

ORR core re-configuration measurements to increase the fast neutron flux in the Magnetic Fusion Energy (MFE) experiments

International Nuclear Information System (INIS)

Hobbs, R.W.; Stinnett, R.M.; Sims, T.M.

1985-06-01

A study has been made of the relative increases obtainable in the fast neutron flux in the Magnetic Fusion Energy (MFE) experiment positions by reconfiguring the current ORR core. The study was made at the request of the MFE program to examine the percentage increase possible in the current displacement per atom (dpa) rate (assumed proportional to the fast flux). The principle methods investigated to increase the fast flux consisted of reducing the current core size (number of fuel elements) to increase the core average power density and arrangement of the fuel elements in the reduced-size core to tilt the core power distribution towards the MFE positions. The study concluded that fast fluxes in the E-3 core position could be increased by approximately 15 to 20% over current values and in E-5 by approximately 45 to 55%

Fusion power: the transition from fundamental science to fusion reactor engineering

International Nuclear Information System (INIS)

Post, R.F.

1975-01-01

The historical development of fusion research is outlined. The basics of fusion power along with fuel cost and advantages of fusion are discussed. Some quantitative requirements for fusion power are described. (MOW)

Fusion Canada

International Nuclear Information System (INIS)

1987-07-01

This first issue of a quarterly newsletter announces the startup of the Tokamak de Varennes, describes Canada's national fusion program, and outlines the Canadian Fusion Fuels Technology Program. A map gives the location of the eleven principal fusion centres in Canada. (L.L.)

An Approach to Automated Fusion System Design and Adaptation

Directory of Open Access Journals (Sweden)

Alexander Fritze

2017-03-01

Full Text Available Industrial applications are in transition towards modular and flexible architectures that are capable of self-configuration and -optimisation. This is due to the demand of mass customisation and the increasing complexity of industrial systems. The conversion to modular systems is related to challenges in all disciplines. Consequently, diverse tasks such as information processing, extensive networking, or system monitoring using sensor and information fusion systems need to be reconsidered. The focus of this contribution is on distributed sensor and information fusion systems for system monitoring, which must reflect the increasing flexibility of fusion systems. This contribution thus proposes an approach, which relies on a network of self-descriptive intelligent sensor nodes, for the automatic design and update of sensor and information fusion systems. This article encompasses the fusion system configuration and adaptation as well as communication aspects. Manual interaction with the flexibly changing system is reduced to a minimum.

An Approach to Automated Fusion System Design and Adaptation.

Science.gov (United States)

Fritze, Alexander; Mönks, Uwe; Holst, Christoph-Alexander; Lohweg, Volker

2017-03-16

Industrial applications are in transition towards modular and flexible architectures that are capable of self-configuration and -optimisation. This is due to the demand of mass customisation and the increasing complexity of industrial systems. The conversion to modular systems is related to challenges in all disciplines. Consequently, diverse tasks such as information processing, extensive networking, or system monitoring using sensor and information fusion systems need to be reconsidered. The focus of this contribution is on distributed sensor and information fusion systems for system monitoring, which must reflect the increasing flexibility of fusion systems. This contribution thus proposes an approach, which relies on a network of self-descriptive intelligent sensor nodes, for the automatic design and update of sensor and information fusion systems. This article encompasses the fusion system configuration and adaptation as well as communication aspects. Manual interaction with the flexibly changing system is reduced to a minimum.

Canada's Fusion Program

International Nuclear Information System (INIS)

Jackson, D. P.

1990-01-01

Canada's fusion strategy is based on developing specialized technologies in well-defined areas and supplying these technologies to international fusion projects. Two areas are specially emphasized in Canada: engineered fusion system technologies, and specific magnetic confinement and materials studies. The Canadian Fusion Fuels Technology Project focuses on the first of these areas. It tritium and fusion reactor fuel systems, remote maintenance and related safety studies. In the second area, the Centre Canadian de fusion magnetique operates the Tokamak de Varennes, the main magnetic fusion device in Canada. Both projects are partnerships linking the Government of Canada, represented by Atomic Energy of Canada Limited, and provincial governments, electrical utilities, universities and industry. Canada's program has extensive international links, through which it collaborates with the major world fusion programs, including participation in the International Thermonuclear Experimental Reactor project

Atomic fusion, Gerrard atomic fusion

International Nuclear Information System (INIS)

Gerrard, T.H.

1980-01-01

In the approach to atomic fusion described here the heat produced in a fusion reaction, which is induced in a chamber by the interaction of laser beams and U.H.F. electromagnetic beams with atom streams, is transferred to a heat exchanger for electricity generation by a coolant flowing through a jacket surrounding the chamber. (U.K.)

Finnish Fusion Research Programme Yearbook 1993-1994

International Nuclear Information System (INIS)

Karttunen, S.; Paettikangas, T.

1995-05-01

Finnish Fusion Research Programme (FFUSION) is one of the national energy research programmes funded by the Ministry of Trade and Industry and from 1995 by TEKES. National organization for fusion research is necessary for efficient and successful participation in international fusion programmes. FFUSION programme serves well for this purpose and it made possible to establish relations and the dialogue with the European Fusion Programme. The process led to the Finnish Association Euratom-TEKES in early 1995. The first period of the FFUSION programme (1993-1994) was preparation for the association to the Community Programme. The strategy was to emphasize fusion technology parallel with the basic fusion and plasma physics and to activate the related Finnish industry to collaborate and participate in the FFUSION programme and later in the European Fusion Programme. The key element in the strategy is the focusing our fairly small R and D effort to a few topics, which increases possibilities to be competitive in Europe. The physics programme in FFUSION deals mainly with theoretical and computational studies of radio-frequency heating in tokamak plasmas. Technology programme started with prestudies in 1993 and it concentrates into two areas: fusion reactor materials and remote handling systems. (8 figs., 3 tabs.)

Advanced nuclear fuel production by using fission-fusion hybrid reactor

International Nuclear Information System (INIS)

Al-Kusayer, T.A.; Sahin, S.; Abdulraoof, M.

1993-01-01

Efforts are made at the College of Engineering, King Saud University, Riyadh to lay out the main structure of a prototype experimental fusion and fusion-fission (hybrid) reactor blanket in cylindrical geometry. The geometry is consistent with most of the current fusion and hybrid reactor design concepts in respect of the neutronic considerations. Characteristics of the fusion chamber, fusion neutrons and the blanket are provided. The studies have further shown that 1 GWe fission-fusion reactor can produce up to 957 kg/year which is enough to fuel five light water reactors of comparable power. Fuel production can be increased further. 29 refs

Comparison of three calcium phosphate bone graft substitutes from biomechanical, histological, and crystallographic perspectives using a rat posterolateral lumbar fusion model

Energy Technology Data Exchange (ETDEWEB)

Hu, Ming-Hsien [Department of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan (China); Department of Orthopedics, Show-Chwan Memorial Hospital, Changhua 50544, Taiwan (China); Department of Orthopedic Surgery, Faculty of Medicine, National Yang-Ming University, Taipei 112, Taiwan (China); Lee, Pei-Yuan [Department of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan (China); Department of Orthopedics, Show-Chwan Memorial Hospital, Changhua 50544, Taiwan (China); Chen, Wen-Cheng, E-mail: wincheng0925@yahoo.com.tw [Department of Fiber and Composite Materials, College of Engineering, Feng Chia University, Taichung 40724, Taiwan (China); Hu, Jin-Jia, E-mail: jjhu@mail.ncku.edu.tw [Department of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan (China); Medical Device Innovation Center, National Cheng Kung University, Tainan 701, Taiwan (China)

2014-12-01

This study evaluated the effectiveness of three calcium phosphate bone graft substitutes with different chemical compositions on spinal fusion using a rat posterolateral lumbar fusion model. Specifically, two recently developed non-dispersive tetracalcium phosphate/dicalcium phosphate anhydrous-based calcium phosphate cements (CPCs), namely a CPC consisting of equimolar amounts of the two compounds (nd-CPC) and a CPC consisting of a two-fold greater amount of dicalcium phosphate anhydrous (DCP-rich CPC), were compared with a commercial calcium phosphate bone graft (c-CPG) consisting of hydroxyapatite (60%) and β-tricalcium phosphate (40%). Single-level posterolateral lumbar fusion was performed at the L4–L5 vertebrae in fifteen adult rats (n = 5 for each group). Spinal fusion was evaluated with radiographs, manual palpation, mechanical testing, micro-CT, and histology 8 weeks post-surgery. In particular, the crystallographic phases in the three substitutes were identified before and 8 weeks after their implantation. Manual palpation revealed stable constructs in nearly all of the spine specimens. The stiffness and bending load of fused spines in the two CPC groups were comparable to those in the c-CPG group. The radiographs specifically revealed implant resorption and bone remodeling in the DCP-rich CPC group. Analysis of 3D micro-CT images revealed that the bone volume ratio in the DCP-rich CPC group was significantly greater than those in the nd-CPC and c-CPG groups. Histology showed that the DCP-rich CPC group exhibited the highest degree of bone regeneration and osseointegration. Notably, DCP-rich CPC led to a pronounced phase transformation, generating the greatest amount of poorly crystalline apatite among the three groups, which together with adequate resorption may explain the aforementioned positive findings. We therefore conclude that of the bone graft substitutes considered, DCP-rich CPC has the greatest potential to be used in spinal fusion

Investigation of spherical and concentric mechanism of compound droplets

Directory of Open Access Journals (Sweden)

Meifang Liu

2016-07-01

Full Text Available Polymer shells with high sphericity and uniform wall thickness are always needed in the inertial confined fusion (ICF experiments. Driven by the need to control the shape of water-in-oil (W1/O compound droplets, the effects of the density matching level, the interfacial tension and the rotation speed of the continuing fluid field on the sphericity and wall thickness uniformity of the resulting polymer shells were investigated and the spherical and concentric mechanisms were also discussed. The centering of W1/O compound droplets, the location and movement of W1/O compound droplets in the external phase (W2 were significantly affected by the density matching level of the key stage and the rotation speed of the continuing fluid field. Therefore, by optimizing the density matching level and rotation speed, the batch yield of polystyrene (PS shells with high sphericity and uniform wall thickness increased. Moreover, the sphericity also increased by raising the oil/water (O/W2 interfacial tension, which drove a droplet to be spherical. The experimental results show that the spherical driving force is from the interfacial tension affected by the two relative phases, while the concentric driving force, as a resultant force, is not only affected by the three phases, but also by the continuing fluid field. The understanding of spherical and concentric mechanism can provide some guidance for preparing polymer shells with high sphericity and uniform wall thickness.

Transgenic plants expressing the AaIT/GNA fusion protein show increased resistance and toxicity to both chewing and sucking pests.

Science.gov (United States)

Liu, Shu-Min; Li, Jie; Zhu, Jin-Qi; Wang, Xiao-Wei; Wang, Cheng-Shu; Liu, Shu-Sheng; Chen, Xue-Xin; Li, Sheng

2016-04-01

The adoption of pest-resistant transgenic plants to reduce yield losses and decrease pesticide use has been successful. To achieve the goal of controlling both chewing and sucking pests in a given transgenic plant, we generated transgenic tobacco, Arabidopsis, and rice plants expressing the fusion protein, AaIT/GNA, in which an insecticidal scorpion venom neurotoxin (Androctonus australis toxin, AaIT) is fused to snowdrop lectin (Galanthus nivalis agglutinin, GNA). Compared with transgenic tobacco and Arabidopsis plants expressing AaIT or GNA, transgenic plants expressing AaIT/GNA exhibited increased resistance and toxicity to one chewing pest, the cotton bollworm, Helicoverpa armigera. Transgenic tobacco and rice plants expressing AaIT/GNA showed increased resistance and toxicity to two sucking pests, the whitefly, Bemisia tabaci, and the rice brown planthopper, Nilaparvata lugens, respectively. Moreover, in the field, transgenic rice plants expressing AaIT/GNA exhibited a significant improvement in grain yield when infested with N. lugens. This study shows that expressing the AaIT/GNA fusion protein in transgenic plants can be a useful approach for controlling pests, particularly sucking pests which are not susceptible to the toxin in Bt crops. © 2015 Institute of Zoology, Chinese Academy of Sciences.

Fusion reactor safety

International Nuclear Information System (INIS)

1987-12-01

Nuclear fusion could soon become a viable energy source. Work in plasma physics, fusion technology and fusion safety is progressing rapidly in a number of Member States and international collaboration continues on work aiming at the demonstration of fusion power generation. Safety of fusion reactors and technological and radiological aspects of waste management are important aspects in the development and design of fusion machines. In order to provide an international forum to review and discuss the status and the progress made since 1983 in programmes related to operational safety aspects of fusion reactors, their waste management and decommissioning concepts, the IAEA had organized the Technical Committee on ''Fusion Reactor Safety'' in Culham, 3-7 November 1986. All presentations of this meeting were divided into four sessions: 1. Statements on National-International Fusion Safety Programmes (5 papers); 2. Operation and System Safety (15 papers); 3. Waste Management and Decommissioning (5 papers); 4. Environmental Impacts (6 papers). A separate abstract was prepared for each of these 31 papers. Refs, figs, tabs

Fusion systems engineering

International Nuclear Information System (INIS)

Anon.

1978-01-01

Research during this report period has covered the following areas: (1) fusion reactor systems studies, (2) development of blanket processing technology for fusion reactors, (3) safety studies of fusion concepts, (4) MACKLIB-IV, a new library of nuclear response functions, (5) energy storage and power supply requirements for commercial fusion reactors, (6) blanket/shield design evaluation for commercial fusion reactors, and (7) cross section measurements, evaluations, and techniques

Anterior cervical fusion: the role of anterior plating.

Science.gov (United States)

Daffner, Scott D; Wang, Jeffrey C

2009-01-01

Treatment of cervical pathology requires a clear understanding of the biomechanical benefits and limitations of cervical plates, their indications, and their associated complications. The use of anterior cervical plates has evolved significantly since their early application in cervical trauma. They have become widely used for anterior cervical decompression and fusion for cervical spondylosis. Plate design has undergone significant refinement and innovation, from the initial unlocked plates requiring bicortical purchase to the latest rotationally and translationally semiconstrained dynamic plates. Excellent clinical results have been reported for single-level anterior cervical decompression and fusion with or without plate fixation; however, the addition of an anterior cervical plate clearly leads to earlier fusion and better clinical results in longer fusions. Longer fusions should ideally consist of corpectomies and strut grafting because the decreased number of fusion surfaces tends to lead to higher fusion rates. Although anterior plate fixation leads to higher fusion rates in fusions of three or more levels, the associated pseudarthrosis rate is still high. The use of dynamic plates, through increased load sharing across the graft and decreased stress shielding, may improve fusion rates, particularly in long fusions. Nevertheless, adjuvant posterior fixation is recommended for fusions of more than three vertebral levels. Anterior plate fixation may be of particular benefit in the management of traumatic injuries, in revision settings, and in the treatment of smokers. Complications unique to plate fixation include hardware breakage and migration as well as ossification of the adjacent disk levels.

A compensatory mutation provides resistance to disparate HIV fusion inhibitor peptides and enhances membrane fusion.

Directory of Open Access Journals (Sweden)

Matthew P Wood

Full Text Available Fusion inhibitors are a class of antiretroviral drugs used to prevent entry of HIV into host cells. Many of the fusion inhibitors being developed, including the drug enfuvirtide, are peptides designed to competitively inhibit the viral fusion protein gp41. With the emergence of drug resistance, there is an increased need for effective and unique alternatives within this class of antivirals. One such alternative is a class of cyclic, cationic, antimicrobial peptides known as θ-defensins, which are produced by many non-human primates and exhibit broad-spectrum antiviral and antibacterial activity. Currently, the θ-defensin analog RC-101 is being developed as a microbicide due to its specific antiviral activity, lack of toxicity to cells and tissues, and safety in animals. Understanding potential RC-101 resistance, and how resistance to other fusion inhibitors affects RC-101 susceptibility, is critical for future development. In previous studies, we identified a mutant, R5-tropic virus that had evolved partial resistance to RC-101 during in vitro selection. Here, we report that a secondary mutation in gp41 was found to restore replicative fitness, membrane fusion, and the rate of viral entry, which were compromised by an initial mutation providing partial RC-101 resistance. Interestingly, we show that RC-101 is effective against two enfuvirtide-resistant mutants, demonstrating the clinical importance of RC-101 as a unique fusion inhibitor. These findings both expand our understanding of HIV drug-resistance to diverse peptide fusion inhibitors and emphasize the significance of compensatory gp41 mutations.

Fusion evaporation residues and the distribution of reaction strength in 16O + 40Ca and 28Si + 28Si reactions

International Nuclear Information System (INIS)

Kolata, J.J.; Hinnefeld, J.; Kovar, D.G.

1985-01-01

In measurements performed previously at ANL, studying the two entrance channels 16 O + 40 Ca and 28 Si + 28 Si which form the same compound nucleus 56 Ni, it was found that at higher bombarding energies (E/sub Lab/ > 5-7 MeV/nucleon) the distributions of reaction strength was dramatically different. Although the total reaction cross section behaviors for the two entrance channels are similar, the total evaporation residue (ER) cross sections for 28 Si + 28 Si decrease rapidly with increasing bombarding energies and up to the highest energy studied show no evidence for incomplete fusion processes. For 16 O + 40 Ca the ER cross section remains constant at approximately 1 barn with increasing bombarding energy and shows evidence of increasing contributions from incomplete fusion. To better understand this apparent dependence on the mass asymmetry in the entrance channel, coincidence measurements between evaporation residue-like products and heavy ions on the opposite side of the beam were performed for the two systems at E/sub Lab/ = 8 MeV/nucleon

Near-barrier Fusion Evaporation and Fission of 28Si+174Yb and 32S+170Er

Science.gov (United States)

Wang, Dongxi; Lin, Chengjian; Jia, Huiming; Ma, Nanru; Sun, Lijie; Xu, Xinxing; Yang, Lei; Yang, Feng; Zhang, Huanqiao; Bao, Pengfei

2017-11-01

Fusion evaporation residues and fission fragments have been measured, respectively, at energies around the Coulomb barrier for the 28Si+174Yb and 32S+170Er systems forming the same compound nucleus 202Po. The excitation function of fusion evaporation, fission as well as capture reactions were deduced. Coupled-channels analyses reveal that couplings to the deformations of targets and the two-phonon states of projectiles contribute much to the enhancement of capture cross sections at sub-barrier energies. The mass and total kinetic energy of fission fragments were deduced by the time-difference method assuming full momentum transfer in a two-body kinematics. The mass-energy and mass-angle distributions were obtained and no obvious quasi-fission components were observed in this bombarding energy range. Further, mass distributions of fission fragments were fitted to extract their widths. Results show that the mass widths decrease monotonically with decreasing energy, but might start to increase when Ec.m./VB < 0.95 for both systems.

Experimental study of the fusion dynamics of 32,34S + 197Au with quasi-elastic scattering

International Nuclear Information System (INIS)

Schuck, T.J.; Dasgupta, M.; Timmers, H.

2000-01-01

Full text: The fusion dynamics of heavy systems, such as 64 Ni + 208 Pb, leading to the synthesis of super-heavy elements is presently not fully understood. Typical beam energies in such reactions are of the order or smaller than the Coulomb barrier height to minimize the excitation energy of the compound system and increase the survival probability of evaporation residues. It is known that at such energies the relative motion of projectile and target couples to internal degrees of freedom of the system, such as collective motion and particle transfer. This can give rise to a distribution of fusion barriers, which generally leads to an enhancement of the fusion cross-section below the Coulomb barrier. The important role of the individual degrees of freedom can be identified by extracting representations of the barrier distribution from fusion excitation functions. Complementary representations can be obtained from measurements of the quasi-elastic or elastic scattering excitation functions at backward angles. The sensitivity of the representations from scattering is limited to the lower energy part of the barrier distribution, which, however, may contain important signatures of positive Q-value neutron transfer channels. Neutron transfer may be a precursor of neutron flow and neck-formation, which are considered in macroscopic models of the fusion of heavy systems. In order to study the influence of neutron transfer in heavy fusion reactions, quasielastic scattering has been measured for 32 , 34 S + 197 Au at energies spanning the Coulomb barrier. The quasi-elastic yield, including inelastic and transfer reactions, was detected at 165 deg with a Si-surface barrier detector. The excitation functions have been normalized to Rutherford scattering, detected at 30 deg using an existing gas ionisation detector. Representations of the barrier distributions have been extracted and are compared with earlier measurements for 32 S + 208 Pb

Laser for fusion energy

International Nuclear Information System (INIS)

Holzrichter, J.F.

1995-01-01

Solid state lasers have proven to be very versatile tools for the study and demonstration of inertial confinement fusion principles. When lasers were first contemplated to be used for the compression of fusion fuel in the late 1950s, the laser output energy levels were nominally one joule and the power levels were 10 3 watts (pulse duration's of 10 -3 sec). During the last 25 years, lasers optimized for fusion research have been increased in power to typically 100,000 joules with power levels approaching 10 14 watts. As a result of experiments with such lasers at many locations, DT target performance has been shown to be consistent with high gain target output. However, the demonstration of ignition and gain requires laser energies of several megajoules. Laser technology improvements demonstrated over the past decade appear to make possible the construction of such multimegajoule lasers at affordable costs. (author)

Odd-Z Transactinide Compound Nucleus Reactions Including the Discovery of 260Bh

Energy Technology Data Exchange (ETDEWEB)

Nelson, Sarah L. [Univ. of California, Berkeley, CA (United States)

2008-01-01

Several reactions producing odd-Z transactinide compound nuclei were studiedwith the 88-Inch Cyclotron and the Berkeley Gas-Filled Separator at the Lawrence Berkeley National Laboratory. The goal was to produce the same compound nucleus ator near the same excitation energy with similar values of angular momentum via differentnuclear reactions. In doing so, it can be determined if there is a preference in entrancechannel, because under these experimental conditions the survival portion of Swiatecki, Siwek-Wilcznska, and Wilczynski's"Fusion By Diffusion" model is nearly identical forthe two reactions. Additionally, because the same compound nucleus is produced, theexit channel is the same. Four compound nuclei were examined in this study: ²⁵⁸Db, ²⁶²Bh, ²⁶⁶Mt, and ²⁷²Rg. These nuclei were produced by using very similar heavy-ion induced-fusion reactions which differ only by one proton in the projectile or target nucleus (e.g.: ⁵⁰Ti + ²⁰⁹Bi vs. ⁵¹V + ²⁰⁸Pb). Peak 1n exit channel cross sections were determined for each reaction in each pair, and three of the four pairs' cross sections were identical within statistical uncertainties. This indicates there is not an obvious preference of entrancechannel in these paired reactions. Charge equilibration immediately prior to fusionleading to a decreased fusion barrier is the likely cause of this phenomenon. In addition to this systematic study, the lightest isotope of element 107, bohrium, was discovered in the ²⁰⁹Bi(⁵²Cr,n) reaction. ²⁶⁰Bh was found to decay by emission of a 10.16 MeV alpha particle with a half-life of 35$+19\\atop{-9}$ ms. The cross section is 59 pb at an excitation energy of 15.0 MeV. The effect of the N = 152 shell is also seen in this isotope's alpha particle energy, the first evidence of such an effect in Bh. All reactions studied are also compared to model predictions by Swiatecki

Barriers to fusion

International Nuclear Information System (INIS)

Berriman, A.C.; Butt, R.D.; Dasgupta, M.; Hinde, D.J.; Morton, C.R.; Newton, J.O.

1999-01-01

The fusion barrier is formed by the combination of the repulsive Coulomb and attractive nuclear forces. Recent research at the Australian National University has shown that when heavy nuclei collide, instead of a single fusion barrier, there is a set of fusion barriers. These arise due to intrinsic properties of the interacting nuclei such deformation, rotations and vibrations. Thus the range of barrier energies depends on the properties of both nuclei. The transfer of matter between nuclei, forming a neck, can also affect the fusion process. High precision data have been used to determine fusion barrier distributions for many nuclear reactions, leading to new insights into the fusion process

Fusion systems engineering

International Nuclear Information System (INIS)

Anon.

1977-01-01

Summaries of research are included for each of the following topics: (1) fusion reactor systems studies, (2) development of blanket processing technology for fusion reactors, (3) safety studies of fusion concepts, (4) the MACK/MACKLIB system for nuclear response functions, and (5) energy storage and power supply systems for fusion reactors

Increase in the strength characteristics of Portland cement due to introduction of the compound mineral supplements

Science.gov (United States)

Il'ina, Liliia; Gichko, Nikolai; Mukhina, Irina

2016-01-01

At the initial phase of hardening it is the limestone component that plays a major role in the hardening process, which acts as the substrate for the crystallization of hydrate tumors due to its chemical affinity with the products of Portland cement hydration. After 7 days, the diopside supplement influences the processes more significantly. Diopside has a high modulus of elasticity compared to the cement paste. As a result, stresses are redistributed within the cement paste and the whole composition is hardened. An increase in the quantity of diopside in the compound supplement to more than 66.7% does not provide a substantial increase in the strength of the cement paste. As the hardness of diopside is higher than the hardness of limestone, much more energy is required to grind it down to a usable component. Therefore, a further increase in the quantity of diopside in the compound supplement is not economically feasible. An evaluation of the optimum quantity of input compound mineral supplements can be made based on the ideas of close packing of spherical particles and the Pauling rules. The optimum content of the supplement is 8-8.5% provided that its dispersion and density are close to the dispersion and density of the binder. An increase in the dispersion of the supplement reduces its optimal quantity.

Historical Perspective on the United States Fusion Program

International Nuclear Information System (INIS)

Dean, Stephen O.

2005-01-01

Progress and Policy is traced over the approximately 55 year history of the U. S. Fusion Program. The classified beginnings of the effort in the 1950s ended with declassification in 1958. The effort struggled during the 1960s, but ended on a positive note with the emergence of the tokamak and the promise of laser fusion. The decade of the 1970s was the 'Golden Age' of fusion, with large budget increases and the construction of many new facilities, including the Tokamak Fusion Test Reactor (TFTR) and the Shiva laser. The decade ended on a high note with the passage of the Magnetic Fusion Energy Engineering Act of 1980, overwhelming approved by Congress and signed by President Carter. The Act called for a '$20 billion, 20 year' effort aimed at construction of a fusion Demonstration Power Plant around the end of the century. The U. S. Magnetic Fusion Energy program has been on a downhill slide since 1980, both in terms of budgets and the construction of new facilities. The Inertial Confinement Fusion program, funded by Department of Energy Defense Programs, has faired considerably better, with the construction of many new facilities, including the National Ignition Facility (NIF)

Fusion energy 2000. Fusion energy 1998 (2001 Edition). Proceedings

International Nuclear Information System (INIS)

2001-01-01

This CD-ROM contains the Proceedings of 18th International Conference on Fusion Energy. It also contains an updated version of the Fusion Energy Conference 1998 Proceedings (38 additional papers included) as well as information on how to use this CD-ROM. The 18th International Atomic Energy Agency Fusion Energy Conference (FEC-2000) was held in Sorrento, Italy, 4-10 October 2000. 573 participants from over thirty countries and three international organizations took part in this Conference. The Conference was organized by the IAEA in co-operation with the Italian National Agency for New Technology, Energy and Environment (ENEA). Around 400 papers were presented in 22 oral and 8 poster sessions on magnetic confinement experiments, inertial fusion energy, plasma heating and current drive, ITER engineering design activities, magnetic confinement theory, innovative concepts, fusion technology, and safety and environment aspects. The 17th International Atomic Energy Agency (IAEA) Fusion Energy Conference was held in Yokohama, Japan, 19-24 October 1999. This 6-day conference, which was attended by 835 participants from over 30 countries and two international organizations, was organized by the IAEA in co-operation with the Japan Atomic Energy Research Institute (JAERI). More than 360 papers plus 5 summary talks were presented in 23 oral and 8 poster sessions on magnetic confinement and experiments, inertial fusion energy, plasma heating and current drive, ITER engineering design activities, magnetic confinement theory, innovative concepts and fusion technology

Stainless steel submerged arc weld fusion line toughness

International Nuclear Information System (INIS)

Rosenfield, A.R.; Held, P.R.; Wilkowski, G.M.

1995-04-01

This effort evaluated the fracture toughness of austenitic steel submerged-arc weld (SAW) fusion lines. The incentive was to explain why cracks grow into the fusion line in many pipe tests conducted with cracks initially centered in SAWS. The concern was that the fusion line may have a lower toughness than the SAW. It was found that the fusion line, Ji. was greater than the SAW toughness but much less than the base metal. Of greater importance may be that the crack growth resistance (JD-R) of the fusion line appeared to reach a steady-state value, while the SAW had a continually increasing JD-R curve. This explains why the cracks eventually turn to the fusion line in the pipe experiments. A method of incorporating these results would be to use the weld metal J-R curve up to the fusion-line steady-state J value. These results may be more important to LBB analyses than the ASME flaw evaluation procedures, since there is more crack growth with through-wall cracks in LBB analyses than for surface cracks in pipe flaw evaluations

Inertial fusion energy; L'energie de fusion inertielle

Energy Technology Data Exchange (ETDEWEB)

Decroisette, M.; Andre, M.; Bayer, C.; Juraszek, D. [CEA Bruyeres-le-Chatel, Dir. des Systemes d' Information (CEA/DIF), 91 (France); Le Garrec, B. [CEA Centre d' Etudes Scientifiques et Techniques d' Aquitaine, 33 - Le Barp (France); Deutsch, C. [Paris-11 Univ., 91 - Orsay (France); Migus, A. [Institut d' Optique Centre scientifique, 91 - Orsay (France)

2005-07-01

We first recall the scientific basis of inertial fusion and then describe a generic fusion reactor with the different components: the driver, the fusion chamber, the material treatment unit, the target factory and the turbines. We analyse the options proposed at the present time for the driver and for target irradiation scheme giving the state of art for each approach. We conclude by the presentation of LMJ (laser Megajoule) and NIF (national ignition facility) projects. These facilities aim to demonstrate the feasibility of laboratory DT ignition, first step toward Inertial Fusion Energy. (authors)

P2X1 Receptor Antagonists Inhibit HIV-1 Fusion by Blocking Virus-Coreceptor Interactions.

Science.gov (United States)

Giroud, Charline; Marin, Mariana; Hammonds, Jason; Spearman, Paul; Melikyan, Gregory B

2015-09-01

HIV-1 Env glycoprotein-mediated fusion is initiated upon sequential binding of Env to CD4 and the coreceptor CXCR4 or CCR5. Whereas these interactions are thought to be necessary and sufficient to promote HIV-1 fusion, other host factors can modulate this process. Previous studies reported potent inhibition of HIV-1 fusion by selective P2X1 receptor antagonists, including NF279, and suggested that these receptors play a role in HIV-1 entry. Here we investigated the mechanism of antiviral activity of NF279 and found that this compound does not inhibit HIV-1 fusion by preventing the activation of P2X1 channels but effectively blocks the binding of the virus to CXCR4 or CCR5. The notion of an off-target effect of NF279 on HIV-1 fusion is supported by the lack of detectable expression of P2X1 receptors in cells used in fusion experiments and by the fact that the addition of ATP or the enzymatic depletion of ATP in culture medium does not modulate viral fusion. Importantly, NF279 fails to inhibit HIV-1 fusion with cell lines and primary macrophages when added at an intermediate stage downstream of Env-CD4-coreceptor engagement. Conversely, in the presence of NF279, HIV-1 fusion is arrested downstream of CD4 binding but prior to coreceptor engagement. NF279 also antagonizes the signaling function of CCR5, CXCR4, and another chemokine receptor, as evidenced by the suppression of calcium responses elicited by specific ligands and by recombinant gp120. Collectively, our results demonstrate that NF279 is a dual HIV-1 coreceptor inhibitor that interferes with the functional engagement of CCR5 and CXCR4 by Env. Inhibition of P2X receptor activity suppresses HIV-1 fusion and replication, suggesting that P2X signaling is involved in HIV-1 entry. However, mechanistic experiments conducted in this study imply that P2X1 receptor is not expressed in target cells or involved in viral fusion. Instead, we found that inhibition of HIV-1 fusion by a specific P2X1 receptor antagonist, NF

Biological effects of activation products and other chemicals released from fusion power plants

International Nuclear Information System (INIS)

Strand, J.A.; Poston, T.M.

1976-09-01

Literature reviews indicate that existing information is incomplete, often contradictory, and of questionable value for the prediction and assessment of ultimate impact from fusion-associated activation products and other chemical releases. It is still uncertain which structural materials will be used in the blanket and first wall of fusion power plants. However, niobium, vanadium, vanadium-chromium alloy, vanadium-titanium alloy, sintered aluminum product, and stainless steel have been suggested. The activation products of principal concern will be the longer-lived isotopes of 26 Al, 49 V, 51 Cr, 54 Mn, 55 Fe, 58 Co, 60 Co, 93 Nb, and 94 Nb. Lithium released to the environment either during the mining cycle, from power plant operation or accident, may be in the form of a number of compound types varying in solubility and affinity for biological organisms. The effects of a severe liquid metal fire or explosion involving Na or K will vary according to inherent abiotic and biotic features of the affected site. Saline, saline-alkaline, and sodic soils of arid lands would be particularly susceptible to alkaline stress. Beryllium released to the environment during the mining cycle or reactor accident situation could be in the form of a number of compound types. Adverse effects to aquatic species from routine chemical releases (biocides, corrosion inhibitors, dissolution products) may occur in the discharge of both fission and fusion power plant designs

Laser fusion overview

International Nuclear Information System (INIS)

Nuckolls, J.

1976-01-01

Because of recent breakthroughs in the target area, and in the glass laser area, the scientific feasibility of laser fusion--and of inertial fusion--may be demonstrated in the early 1980's. Then the development in that time period of a suitable laser (or storage ring or other driving source) would make possible an operational inertial fusion reactor in this century. These are roughly the same time scales as projected by the Tokamak magnetic confinement approach. It thus appears that the 15-20 year earlier start by magnetic confinement fusion may be overcome. Because inertial confinement has been demonstrated, and inertial fusion reactors may operate on smaller scales than Tokamaks, laser fusion may have important technical and economic advantages

Accelerator aspects of heavy ion induced inertial fusion

Energy Technology Data Exchange (ETDEWEB)

Boehme, D

1983-01-01

Besides the possibilities of the magnetic fusion those of inertial fusion have increasingly found interest. Bundled photon and corpuscular beams shall be symetrically focussed from the outside on a pellet with the fusion fuel being compressed far beyond the density of the ordinary solids. Laser, light ion and heavy ion beams can be used as driver beams. The GSI took over the project leadership for a five years' research programme with formulated questions on heavy ion fusion. The project is promoted by the BMFT. During the international symposium the opportunity of intensive discussions on research work in this field in different countries was made use of.

Development of Laser Based Plasma Diagnostics for Fusion Research on NSTX-U

Science.gov (United States)

Barchfeld, Robert Adam

Worldwide demand for power, and in particular electricity, is growing. Increasing population, expanding dependence on electrical devices, as well as the development of emerging nations, has created significant challenges for the power production. Compounding the issue are concerns over pollution, natural resource supplies, and political obstacles in troubled parts of the world. Many believe that investment in renewable energy will solve the expected energy crisis; however, renewable energy has many shortfalls. Consequently, additional sources of energy should be explored to provide the best options for the future. Electricity from fusion power offers many advantages over competing technologies. It can potentially produce large amounts of clean energy, without the serious concerns of fission power plant safety and nuclear waste. Fuel supplies for fusion are plentiful. Fusion power plants can be operated as needed, without dependence on location, or local conditions. However, there are significant challenges before fusion can be realized. Many factors currently limit the effectiveness of fusion power, which prevents a commercial power plant from being feasible. Scientists in many countries have built, and operate, experimental fusion plants to study the fusion process. The leading examples are magnetic confinement reactors known as tokamaks. At present, reactor gain is near unity, where the fusion power output is nearly the same as the power required to operate the reactor. A tenfold increase in gain is what reactors such as ITER hope to achieve, where 50 MW will be used for plasma heating, magnetic fields, and so forth, with a power output of 500 MW. Before this can happen, further research is required. Loss of particle and energy confinement is a principal cause of low performance; therefore, increasing confinement time is key. There are many causes of thermal and particle transport that are being researched, and the prime tools for conducting this research are

Radiation damage calculations for compound materials

International Nuclear Information System (INIS)

Greenwood, L.R.

1990-01-01

This paper reports on the SPECOMP computer code, developed to calculate neutron-induced displacement damage cross sections for compound materials such as alloys, insulators, and ceramic tritium breeders for fusion reactors. These new calculations rely on recoil atom energy distributions previously computed with the DISCS computer code, the results of which are stored in SPECTER computer code master libraries. All reaction channels were considered in the DISCS calculations and the neutron cross sections were taken from ENDF/B-V. Compound damage calculations with SPECOMP thus do not need to perform any recoil atom calculations and consequently need no access to ENDF or other neutron data bases. The calculations proceed by determining secondary displacements for each combination of recoil atom and matrix atom using the Lindhard partition of the recoil energy to establish the damage energy

Development of Lead Compounds as Fusion Inhibitors for Dengue Virus

Science.gov (United States)

2009-08-01

mixed stereo chemistry ), but no chemical modification was desired because of the high specificity of the fragment definition. This generation...therefore promising candidates for virtual screening, synthesis and biological testing. Out of the generation process, more than 80% of the...size and biological class of compounds (analogs of peptides, alkaloids , anthracyclines, etc.). We therefore have included the prediction of the effect

Membrane fusion

DEFF Research Database (Denmark)

Bendix, Pól Martin

2015-01-01

At Stanford University, Boxer lab, I worked on membrane fusion of small unilamellar lipid vesicles to flat membranes tethered to glass surfaces. This geometry closely resembles biological systems in which liposomes fuse to plasma membranes. The fusion mechanism was studied using DNA zippering...... between complementary strands linked to the two apposing membranes closely mimicking the zippering mechanism of SNARE fusion complexes....

Production and characterization of active recombinant interleukin-12/eGFP fusion protein in stably-transfected DF1 chicken cells.

Science.gov (United States)

Wu, Hsing Chieh; Chen, Yu San; Shen, Pin Chun; Shien, Jui Hung; Lee, Long Huw; Chiu, Hua Hsien

2015-01-01

The adjuvant activity of chicken interleukin-12 (chIL-12) protein has been described as similar to that of mammalian IL-12. Recombinant chIL-12 can be produced using several methods, but chIL-12 production in eukaryotic cells is lower than that in prokaryotic cells. Stimulating compounds, such as dimethyl sulfoxide (DMSO), can be added to animal cell cultures to overcome this drawback. In this study, we constructed a cell line, DF1/chIL-12 which stably expressed a fusion protein, chIL-12 and enhanced green fluorescent protein (eGFP) connected by a (G4 S)3 linker sequence. Fusion protein production was increased when cells were cultured in the presence of DMSO. When 1 × 10(6) DF1/chIL-12 cells were inoculated in a T-175 flask containing 30 mL of media, incubated for 15 h, and further cultivated in the presence of 4% DMSO for 48 h, the production of total fusion protein was mostly enhanced compared with the production of total fusion protein by using cell lysates induced with DMSO at other concentrations. The concentrations of the unpurified and purified total fusion proteins in cell lysates were 2,781 ± 2.72 ng mL(-1) and 2,207 ± 3.28 ng mL(-1) , respectively. The recovery rate was 79%. The fusion protein stimulated chicken splenocytes to produce IFN-γ, which was measured using an enzyme-linked immunosorbent assay, in the culture supernatant, indicating that treating DF1/chIL-12 cells with DMSO or producing chIL-12 in a fusion protein form does not have adverse effects on the bioactivity of chIL-12. © 2015 American Institute of Chemical Engineers.

Past, present and future of the fusion reactors

International Nuclear Information System (INIS)

Rosenbaum P, M.

1992-01-01

Among the alternate technologies that have acquired a special interest in the present decade, we find the nuclear fusion. Within this, the fusion reactors by magnetic confinement of the Tokamak type have shown an increasing technological progress during this period. For this reason, a new strategy, coordinated at international level, has been implemented for the specific development of the nuclear fusion reactors, aimed to face those scientific and technological aspects which still remain, and which will determine their future economic feasibility. (Author)

Vacuum engineering for fusion research and fusion reactors

International Nuclear Information System (INIS)

Pittenger, L.C.

1976-01-01

The following topics are described: (1) surface pumping by cryogenic condensation, (2) operation of large condensing cryopumps, (3) pumping for large fusion experiments, and (4) vacuum technology for fusion reactors

Nuclear fusion

International Nuclear Information System (INIS)

Al-zaelic, M.M.

2013-01-01

Nuclear fusion can be relied on to solve the global energy crisis if the process of limiting the heat produced by the fusion reaction (Plasma) is successful. Currently scientists are progressively working on this aspect whereas there are two methods to limit the heat produced by fusion reaction, the two methods are auto-restriction using laser beam and magnetic restriction through the use of magnetic fields and research is carried out to improve these two methods. It is expected that at the end of this century the nuclear fusion energy will play a vital role in overcoming the global energy crisis and for these reasons, acquiring energy through the use of nuclear fusion reactors is one of the most urge nt demands of all mankind at this time. The conclusion given is that the source of fuel for energy production is readily available and inexpensive ( hydrogen atoms) and whole process is free of risks and hazards, especially to general health and the environment . Nuclear fusion importance lies in the fact that energy produced by the process is estimated to be about four to five times the energy produced by nuclear fission. (author)

Fusion power economy of scale

International Nuclear Information System (INIS)

Dolan, T.J.

1993-01-01

In the next 50 yr, the world will need to develop hundreds of gigawatts of non-fossil-fuel energy sources for production of electricity and fuels. Nuclear fusion can probably provide much of the required energy economically, if large single-unit power plants are acceptable. Large power plants are more common than most people realize: There are already many multiple-unit power plants producing 2 to 5 GW(electric) at a single site. The cost of electricity (COE) from fusion energy is predicted to scale as COE ∼ COE 0 (P/P 0 ) -n , where P is the electrical power, the subscript zero denotes reference values, and the exponent n ∼ 0.36 to 0.7 in various designs. The validity ranges of these scalings are limited and need to be extended by future work. The fusion power economy of scale derives from four interrelated effects: improved operations and maintenance costs; scaling of equipment unit costs; a geometric effect that increases the mass power density; and reduction of the recirculating power fraction. Increased plasma size also relaxes the required confinement parameters: For the same neutron wall loading, larger tokamaks can use lower magnetic fields. Fossil-fuel power plants have a weaker economy of scale than fusion because the fuel costs constitute much of their COE. Solar and wind power plants consist of many small units, so they have little economy of scale. Fission power plants have a strong economy of scale but are unable to exploit it because the maximum unit size is limited by safety concerns. Large, steady-state fusion reactors generating 3 to 6 GW(electric) may be able to produce electricity for 4 to 5 cents/kW·h, which would be competitive with other future energy sources. 38 refs., 6 figs., 6 tabs

History of controlled nuclear fusion in Japan

International Nuclear Information System (INIS)

Uematsu, Eisui; Nishio, Shigeko; Takeda, Tatsuoki

2001-01-01

A research development of nuclear fusion was divided four periods: the first period as prehistory (until about 1955), the second period as begin of research (1955 to 1969), the third as the growth period (1970 to 1985) and the forth as the large tokamak age. In this paper I explained the second period, because general physicists and young plasma and controlled nuclear fusion researcher did not know about this period. The controlled nuclear fusion research was begun by the experiment of hydrogen bomb by USA and USSR in 1952 and 1953. In Japan, on the basis of many societies, 'The Controlled Nuclear Fusion Meeting' was established as an independent system and KAKEA (Journal of Fusion Research) was published in 1958. Japan government began to make the system by the Nuclear Commission in 1957. The main research devices in 1962 were linear pinch, mirror device, toroidal pinch, helical system, plasma gun and plasma measurement. USSR showed the excellent results of tokamak device in 1968. Ookawa spoke the effect of the average minimum-B, the best report in this period, at the second IAEA meeting, 1965. JAERI constructed JFT-1 and JFT-2, the latter was the first class device in the world and made the first step of Japanese research into the world, for examples, to attain the equilibrium of divertor plasma and to control impurity. Many research centers of controlled fusion were established in many universities in Japan from 1966 to 1980. Cooperation researchs between Japan and USA, USSR and many countries has been carried out after 1978: JIFT (Joint Institute for Fusion Theory) and FPPC (Fusion Power Coordinating Committee). The important results increased in this period. After 1985, the research activities are processing and data increased very fast depend on the larger devices and system, good measurement system and development of information system. JT-60 in JAERI opened to the large tokamak period. It led controlled fusion researchs in the world the same as TFTR (US

Conversion of radioactive ferrocyanide compounds to immobile glasses

International Nuclear Information System (INIS)

Schulz, W.W.; Dressen, A.L.

1977-01-01

Complex radioactive ferrocyanide compounds result from the scavenging of cesium from waste products produced in the chemical reprocessing of nuclear fuel. These ferrocyanides, in accordance with this process, are converted to an immobile glass, resistant to leaching by water, by fusion together with sodium carbonate and a mixture of (a) basalt and boron trioxide (B 2 O 3 ) or (b) silica (SiO 2 ) and lime (CaO). 7 claims

Fusion Plasma Theory project summaries

Energy Technology Data Exchange (ETDEWEB)

1993-10-01

This Project Summary book is a published compilation consisting of short descriptions of each project supported by the Fusion Plasma Theory and Computing Group of the Advanced Physics and Technology Division of the Department of Energy, Office of Fusion Energy. The summaries contained in this volume were written by the individual contractors with minimal editing by the Office of Fusion Energy. Previous summaries were published in February of 1982 and December of 1987. The Plasma Theory program is responsible for the development of concepts and models that describe and predict the behavior of a magnetically confined plasma. Emphasis is given to the modelling and understanding of the processes controlling transport of energy and particles in a toroidal plasma and supporting the design of the International Thermonuclear Experimental Reactor (ITER). A tokamak transport initiative was begun in 1989 to improve understanding of how energy and particles are lost from the plasma by mechanisms that transport them across field lines. The Plasma Theory program has actively-participated in this initiative. Recently, increased attention has been given to issues of importance to the proposed Tokamak Physics Experiment (TPX). Particular attention has been paid to containment and thermalization of fast alpha particles produced in a burning fusion plasma as well as control of sawteeth, current drive, impurity control, and design of improved auxiliary heating. In addition, general models of plasma behavior are developed from physics features common to different confinement geometries. This work uses both analytical and numerical techniques. The Fusion Theory program supports research projects at US government laboratories, universities and industrial contractors. Its support of theoretical work at universities contributes to the office of Fusion Energy mission of training scientific manpower for the US Fusion Energy Program.

Fusion plasma theory project summaries

Science.gov (United States)

1993-10-01

This Project Summary book is a published compilation consisting of short descriptions of each project supported by the Fusion Plasma Theory and Computing Group of the Advanced Physics and Technology Division of the Department of Energy, Office of Fusion Energy. The summaries contained in this volume were written by the individual contractors with minimal editing by the Office of Fusion Energy. Previous summaries were published in February of 1982 and December of 1987. The Plasma Theory program is responsible for the development of concepts and models that describe and predict the behavior of a magnetically confined plasma. Emphasis is given to the modelling and understanding of the processes controlling transport of energy and particles in a toroidal plasma and supporting the design of the International Thermonuclear Experimental Reactor (ITER). A tokamak transport initiative was begun in 1989 to improve understanding of how energy and particles are lost from the plasma by mechanisms that transport them across field lines. The Plasma Theory program has actively participated in this initiative. Recently, increased attention has been given to issues of importance to the proposed Tokamak Physics Experiment (TPX). Particular attention has been paid to containment and thermalization of fast alpha particles produced in a burning fusion plasma as well as control of sawteeth, current drive, impurity control, and design of improved auxiliary heating. In addition, general models of plasma behavior are developed from physics features common to different confinement geometries. This work uses both analytical and numerical techniques. The Fusion Theory program supports research projects at U.S. government laboratories, universities and industrial contractors. Its support of theoretical work at universities contributes to the office of Fusion Energy mission of training scientific manpower for the U.S. Fusion Energy Program.

Fusion Plasma Theory project summaries

International Nuclear Information System (INIS)

1993-10-01

This Project Summary book is a published compilation consisting of short descriptions of each project supported by the Fusion Plasma Theory and Computing Group of the Advanced Physics and Technology Division of the Department of Energy, Office of Fusion Energy. The summaries contained in this volume were written by the individual contractors with minimal editing by the Office of Fusion Energy. Previous summaries were published in February of 1982 and December of 1987. The Plasma Theory program is responsible for the development of concepts and models that describe and predict the behavior of a magnetically confined plasma. Emphasis is given to the modelling and understanding of the processes controlling transport of energy and particles in a toroidal plasma and supporting the design of the International Thermonuclear Experimental Reactor (ITER). A tokamak transport initiative was begun in 1989 to improve understanding of how energy and particles are lost from the plasma by mechanisms that transport them across field lines. The Plasma Theory program has actively-participated in this initiative. Recently, increased attention has been given to issues of importance to the proposed Tokamak Physics Experiment (TPX). Particular attention has been paid to containment and thermalization of fast alpha particles produced in a burning fusion plasma as well as control of sawteeth, current drive, impurity control, and design of improved auxiliary heating. In addition, general models of plasma behavior are developed from physics features common to different confinement geometries. This work uses both analytical and numerical techniques. The Fusion Theory program supports research projects at US government laboratories, universities and industrial contractors. Its support of theoretical work at universities contributes to the office of Fusion Energy mission of training scientific manpower for the US Fusion Energy Program

Aerobic Biofilms Grown from Athabasca Watershed Sediments Are Inhibited by Increasing Concentrations of Bituminous Compounds

Science.gov (United States)

Lawrence, John R.; Sanschagrin, Sylvie; Roy, Julie L.; Swerhone, George D. W.; Korber, Darren R.; Greer, Charles W.

2013-01-01

Sediments from the Athabasca River and its tributaries naturally contain bitumen at various concentrations, but the impacts of this variation on the ecology of the river are unknown. Here, we used controlled rotating biofilm reactors in which we recirculated diluted sediments containing various concentrations of bituminous compounds taken from the Athabasca River and three tributaries. Biofilms exposed to sediments having low and high concentrations of bituminous compounds were compared. The latter were 29% thinner, had a different extracellular polysaccharide composition, 67% less bacterial biomass per μm2, 68% less cyanobacterial biomass per μm2, 64% less algal biomass per μm2, 13% fewer protozoa per cm2, were 21% less productive, and had a 33% reduced content in chlorophyll a per mm2 and a 20% reduction in the expression of photosynthetic genes, but they had a 23% increase in the expression of aromatic hydrocarbon degradation genes. Within the Bacteria, differences in community composition were also observed, with relatively more Alphaproteobacteria and Betaproteobacteria and less Cyanobacteria, Bacteroidetes, and Firmicutes in biofilms exposed to high concentrations of bituminous compounds. Altogether, our results suggest that biofilms that develop in the presence of higher concentrations of bituminous compounds are less productive and have lower biomass, linked to a decrease in the activities and abundance of photosynthetic organisms likely due to inhibitory effects. However, within this general inhibition, some specific microbial taxa and functional genes are stimulated because they are less sensitive to the inhibitory effects of bituminous compounds or can degrade and utilize some bitumen-associated compounds. PMID:24056457

Circumferential fusion improves outcome in comparison with instrumented posterolateral fusion

DEFF Research Database (Denmark)

Videbaek, Tina S; Christensen, Finn B; Soegaard, Rikke

2006-01-01

with respect to all four DPQ categories: daily activities, work/leisure, anxiety/depression, and social interest. The Oswestry Disability Index supported these results (P ...STUDY DESIGN: Prospective randomized clinical study with a 5- to 9-year follow-up period. OBJECTIVE: The aim of the present study was to analyze the long-term outcome with respect to functional disability, pain, and general health of patients treated by means of circumferential lumbar fusion...... in comparison with those treated by means of instrumented posterolateral lumbar fusion. SUMMARY OF BACKGROUND DATA: Circumferential fusion has become a common procedure in lumbar spinal fusion both as a primary and salvage procedure. However, the claimed advantages of circumferential fusion over conventional...

Jazz-Philosophy Fusion

Directory of Open Access Journals (Sweden)

James Tartaglia

2016-07-01

Full Text Available In this paper I describe and provide a justification for the fusion of jazz music and philosophy which I have developed; the justification is provided from the perspectives of both jazz and philosophy. I discuss two of my compositions, based on philosophical ideas presented by Schopenhauer and Derek Parfit respectively; links to sound files are provided. The justification emerging from this discussion is that philosophy produces ‘non-argumentative effects’ which provide suitable material for artistic expression and exploration. These effects – which are often emotional – are under-recognised in philosophy, but they do important philosophical work in demarcating the kinds of truths we want to discover, and in sustaining our search for them. Jazz-Philosophy Fusion can help to increase metaphilosophical self-consciousness about these effects, while also helping to counteract any undue persuasive force they may achieve. Jazz is a particularly suitable medium because it has independently developed a concern with philosophical ideas; because of strong parallels between jazz and philosophy which explain their mutual openness to fusions, and because improvisation very effectively facilitates the direct audience engagement essential to inducing these effects.

Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells

Directory of Open Access Journals (Sweden)

Pittet Anne-Laure

2006-10-01

Full Text Available Abstract Background The Wnt signaling pathway is activated by mutations in the APC and β-catenin genes in many types of human cancer. β-catenin is stabilized by these mutations and activates transcription in part by acting as a bridge between Tcf/LEF proteins and the HD2 domain of the BCL9 coactivator. We have previously described oncolytic adenoviruses with binding sites for Tcf/LEF transcription factors inserted into the early viral promoters. These viruses replicate selectively in cells with activation of the Wnt pathway. To increase the activity of these viruses we have fused the viral transactivator E1A to the BCL9 HD2 domain. Methods Luciferase assays, co-immunoprecipitation and Western blotting, immunofluorescent cell staining and cytopathic effect assays were used to characterize the E1A-HD2 fusion protein and virus in vitro. Growth curves of subcutaneous SW620 colon cancer xenografts were used to characterize the virus in vivo. Results The E1A-HD2 fusion protein binds to β-catenin in vivo and activates a Tcf-regulated luciferase reporter better than wild-type E1A in cells with activated Wnt signaling. Expression of the E1A-HD2 protein promotes nuclear import of β-catenin, mediated by the strong nuclear localization signal in E1A. Tcf-regulated viruses expressing the fusion protein show increased expression of viral proteins and a five-fold increase in cytopathic effect (CPE in colorectal cancer cell lines. There was no change in viral protein expression or CPE in HeLa cells, indicating that E1A-HD2 viruses retain selectivity for cells with activation of the Wnt signaling pathway. Despite increasing the cytopathic effect of the virus in vitro, fusion of the HD2 domain to E1A did not increase the burst size of the virus in vitro or the anti-tumor effect of the virus in an SW620 xenograft model in vivo. Conclusion Despite an increase in the nuclear pool of β-catenin, the effects on viral activity in colon cancer cells were small

A preliminary examination of the economics of cogeneration with fusion plants

International Nuclear Information System (INIS)

Hazelrigg, G.A.; Coleman, D.E.

1983-01-01

Cogeneration, the process of using reject heat from electric energy generation plants, offers substantial savings in energy consumption and thus is likely to see increased implementation, especially in the form of district heating, over the next few decades. The use of fusion plants for cogeneration offers added advantages of potentially low marginal costs and reduced siting restrictions compared to nuclear and coal plants, and freedom from use of limited fossil fuels. Fusion can thus provide increased economic incentive to the implementation of cogeneration systems. Conversely, cogeneration improves the economics of fusion and thus provides both added incentive for its development and reduced economic requirements on commercial fusion technologies

Role of hydrodynamic instability growth in hot-spot mass gain and fusion performance of inertial confinement fusion implosions

International Nuclear Information System (INIS)

Srinivasan, Bhuvana; Tang, Xian-Zhu

2014-01-01

In an inertial confinement fusion target, energy loss due to thermal conduction from the hot-spot will inevitably ablate fuel ice into the hot-spot, resulting in a more massive but cooler hot-spot, which negatively impacts fusion yield. Hydrodynamic mix due to Rayleigh-Taylor instability at the gas-ice interface can aggravate the problem via an increased gas-ice interfacial area across which energy transfer from the hot-spot and ice can be enhanced. Here, this mix-enhanced transport effect on hot-spot fusion-performance degradation is quantified using contrasting 1D and 2D hydrodynamic simulations, and its dependence on effective acceleration, Atwood number, and ablation speed is identified

Study of heavy ion fusion: application to the system 28Si + 28Si

International Nuclear Information System (INIS)

Plagnol, E.

1982-03-01

Study of the fusion reactions between medium mass range heavy ions (experiments on 56 Ni compound nucleus formed by the reaction 28 Si + 28 Si): - analysis of the properties of the compound nucleus de-excitation process: utilization of the evaporation model based on the Hauser-Fesbach statistical model; study of the evolution of the production cross sections of the evaporation residues as a function of the excitation energy and of the angular momentum; - analysis of the kinetics of the compound nucleus formation, with construction of a model describing the various observed regimes, as a function of energy, in the compound nucleus formation cross section: study of the properties of the rotating liquid drop and of the formation kinetics evolution of the nuclei under Coulomb and nuclear potentials, up to a minimal approach distance, sticking conditions, and development towards scission or equilibrium state (compound nucleus) [fr

Energy sweepstakes: fusion gets a chance

International Nuclear Information System (INIS)

Robinson, A.L.

1980-01-01

Congress plans to speed up the magnetic-fusion program by shifting the emphasis from plasma research to fusion-reactor engineering. The bill doubles the overall fusion budget over the next five years in order to construct a Fusion Engineering Device (FED) by 1990. A review panel of scientists suggested limiting the cost to under $1 billion and holding the increase until late 1983. The panel also suggested waiting until 1990 to set a date for demonstrating a competitive commercial reactor even though progress made in the 1970s could bring a realistic date as close as 2000. The new policy evolves from the debate between tokamak hawks, who want to take the best prospect to commercialization immediately, and the doves, who want to wait to see if the best possible concept turns out to be the magnetic mirror or some other contender. The Engineering Test Facility (ETF) represents a compromise of these positions

Information Fusion of Conflicting Input Data

Directory of Open Access Journals (Sweden)

Uwe Mönks

2016-10-01

Full Text Available Sensors, and also actuators or external sources such as databases, serve as data sources in order to realise condition monitoring of industrial applications or the acquisition of characteristic parameters like production speed or reject rate. Modern facilities create such a large amount of complex data that a machine operator is unable to comprehend and process the information contained in the data. Thus, information fusion mechanisms gain increasing importance. Besides the management of large amounts of data, further challenges towards the fusion algorithms arise from epistemic uncertainties (incomplete knowledge in the input signals as well as conflicts between them. These aspects must be considered during information processing to obtain reliable results, which are in accordance with the real world. The analysis of the scientific state of the art shows that current solutions fulfil said requirements at most only partly. This article proposes the multilayered information fusion system MACRO (multilayer attribute-based conflict-reducing observation employing the μBalTLCS (fuzzified balanced two-layer conflict solving fusion algorithm to reduce the impact of conflicts on the fusion result. The performance of the contribution is shown by its evaluation in the scope of a machine condition monitoring application under laboratory conditions. Here, the MACRO system yields the best results compared to state-of-the-art fusion mechanisms. The utilised data is published and freely accessible.

Information Fusion of Conflicting Input Data.

Science.gov (United States)

Mönks, Uwe; Dörksen, Helene; Lohweg, Volker; Hübner, Michael

2016-10-29

Sensors, and also actuators or external sources such as databases, serve as data sources in order to realise condition monitoring of industrial applications or the acquisition of characteristic parameters like production speed or reject rate. Modern facilities create such a large amount of complex data that a machine operator is unable to comprehend and process the information contained in the data. Thus, information fusion mechanisms gain increasing importance. Besides the management of large amounts of data, further challenges towards the fusion algorithms arise from epistemic uncertainties (incomplete knowledge) in the input signals as well as conflicts between them. These aspects must be considered during information processing to obtain reliable results, which are in accordance with the real world. The analysis of the scientific state of the art shows that current solutions fulfil said requirements at most only partly. This article proposes the multilayered information fusion system MACRO (multilayer attribute-based conflict-reducing observation) employing the μ BalTLCS (fuzzified balanced two-layer conflict solving) fusion algorithm to reduce the impact of conflicts on the fusion result. The performance of the contribution is shown by its evaluation in the scope of a machine condition monitoring application under laboratory conditions. Here, the MACRO system yields the best results compared to state-of-the-art fusion mechanisms. The utilised data is published and freely accessible.

Natural thioallyl compounds increase oxidative stress resistance and lifespan in Caenorhabditis elegans by modulating SKN-1/Nrf.

Science.gov (United States)

Ogawa, Takahiro; Kodera, Yukihiro; Hirata, Dai; Blackwell, T Keith; Mizunuma, Masaki

2016-02-22

Identification of biologically active natural compounds that promote health and longevity, and understanding how they act, will provide insights into aging and metabolism, and strategies for developing agents that prevent chronic disease. The garlic-derived thioallyl compounds S-allylcysteine (SAC) and S-allylmercaptocysteine (SAMC) have been shown to have multiple biological activities. Here we show that SAC and SAMC increase lifespan and stress resistance in Caenorhabditis elegans and reduce accumulation of reactive oxygen species (ROS). These compounds do not appear to activate DAF-16 (FOXO orthologue) or mimic dietary restriction (DR) effects, but selectively induce SKN-1 (Nrf1/2/3 orthologue) targets involved in oxidative stress defense. Interestingly, their treatments do not facilitate SKN-1 nuclear accumulation, but slightly increased intracellular SKN-1 levels. Our data also indicate that thioallyl structure and the number of sulfur atoms are important for SKN-1 target induction. Our results indicate that SAC and SAMC may serve as potential agents that slow aging.

What fusion means to Canada

International Nuclear Information System (INIS)

Bolton, R.A.

1983-06-01

Fusion can and will play an ever-increasing role in the energy balance once it has been brought on line. Taming of this technology and the maturing processes of engineering and economic feasibility will proceed at a rate which depends very strongly upon international and collective national wills to see it through. Large experimental devices, particularly of the tokamak type, are now being completed; their performance should give a very good idea of the scientific feasibility. The next-stage devices are at the pre-proposal and proposal stages but are not yet approved, even in principle. An improved general economic climate sustained for a few years would certainly help re-establish the momentum of world international efforts in fusion. This paper gives an overview of fusion research on a world scale and details of the particular aspects that Canada has chosen to pursue

Progress in fusion technology in the U.S. magnetic fusion program

International Nuclear Information System (INIS)

Dowling, R.J.; Beard, D.S.; Haas, G.M.; Stone, P.M.; George, T.V.

1987-01-01

In this paper the authors discuss the major technological achievements that have taken place during the past few years in the U.S. magnetic fusion program which have contributed to the global efforts. The goal has been to establish the scientific and technological base required for fusion energy. To reach this goal the fusion RandD program is focused on four key technical issues: determine the optimum configuration of magnetic confinement systems; determine the properties of burning plasmas; develop materials for fusion systems; and establish the nuclear technology of fusion systems. The objective of the fusion technology efforts has been to develop advanced technologies and provide the necessary support for research of these four issues. This support is provided in a variety of areas such as: high vacuum technology, large magnetic field generation by superconducting and copper coils, high voltage and high current power supplies, electromagnetic wave and particle beam heating systems, plasma fueling, tritium breeding and handling, remote maintenance, energy recovery. The U.S. Fusion Technology Program provides major support or has the primary responsibility in each of the four key technical issues of fusion, as described in the Magnetic Fusion Program Plan of February 1985. This paper has summarized the Technology Program in terms of its activities and progress since the Proceedings of the SOFT Conference in 1984

FuzzyFusion: an application architecture for multisource information fusion

Science.gov (United States)

Fox, Kevin L.; Henning, Ronda R.

2009-04-01

The correlation of information from disparate sources has long been an issue in data fusion research. Traditional data fusion addresses the correlation of information from sources as diverse as single-purpose sensors to all-source multi-media information. Information system vulnerability information is similar in its diversity of sources and content, and in the desire to draw a meaningful conclusion, namely, the security posture of the system under inspection. FuzzyFusionTM, A data fusion model that is being applied to the computer network operations domain is presented. This model has been successfully prototyped in an applied research environment and represents a next generation assurance tool for system and network security.

Important atomic physics issues for ion beam fusion

International Nuclear Information System (INIS)

Bangerter, Roger.

1986-01-01

The nearly endless variety of interesting and challenging problems makes physics research enjoyable. Most of us would choose to be physicists even if physics had no practical applications. However, physics does have practical applications. This workshop deals with one of those applications, namely ion beam fusion. Not all interesting and challenging atomic physics questions are important for ion beam fusion. This paper suggests some questions that may be important for ion beam fusion. It also suggests some criteria for determining if a question is only interesting, or both interesting and important. Importance is time dependent and, because of some restrictions on the flow of information, also country dependent. In the early days of ion beam fusion, it was important to determine if ion beam fusion made sense. Approximate answers and bounds on various parameters were required. Accurate, detailed answers were not needed. Because of the efforts of many people attending this workshop, we now know that ion beam fusion does make some sense. We must still determine if ion beam fusion truly makes good sense. If it does make good sense, we must determine how to make it work. Accurate detailed answers are becoming increasingly important. (author)

Ch. 37, Inertial Fusion Energy Technology

International Nuclear Information System (INIS)

Moses, E.

2010-01-01

Nuclear fission, nuclear fusion, and renewable energy (including biofuels) are the only energy sources capable of satisfying the Earth's need for power for the next century and beyond without the negative environmental impacts of fossil fuels. Substantially increasing the use of nuclear fission and renewable energy now could help reduce dependency on fossil fuels, but nuclear fusion has the potential of becoming the ultimate base-load energy source. Fusion is an attractive fuel source because it is virtually inexhaustible, widely available, and lacks proliferation concerns. It also has a greatly reduced waste impact, and no danger of runaway reactions or meltdowns. The substantial environmental, commercial, and security benefits of fusion continue to motivate the research needed to make fusion power a reality. Replicating the fusion reactions that power the sun and stars to meet Earth's energy needs has been a long-sought scientific and engineering challenge. In fact, this technological challenge is arguably the most difficult ever undertaken. Even after roughly 60 years of worldwide research, much more remains to be learned. the magnitude of the task has caused some to declare that fusion is 20 years away, and always will be. This glib criticism ignores the enormous progress that has occurred during those decades, progress inboth scientific understanding and essential technologies that has enabled experiments producing significant amounts of fusion energy. For example, more than 15 megawatts of fusion power was produced in a pulse of about half a second. Practical fusion power plants will need to produce higher powers averaged over much longer periods of time. In addition, the most efficient experiments to date have required using about 50% more energy than the resulting fusion reaction generated. That is, there was no net energy gain, which is essential if fusion energy is to be a viable source of electricity. The simplest fusion fuels, the heavy isotopes of

The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein

International Nuclear Information System (INIS)

Semaan, Sheila J; Nickells, Robert W

2010-01-01

Many chemotherapeutic agents promote tumor cell death by activating the intrinsic pathway of apoptosis. Intrinsic apoptosis involves permeabilization of the mitochondrial outer membrane and the release of cytochrome c, a process that is controlled by proteins of the BCL2 gene family. Chemoresistance is often associated with abnormalities in concentrations of BCL2 family proteins. Although stoichiometirc interactions between anti-apoptotic and BH3-only BCL2 family proteins have been well documented as affecting cell death, the association between changes in BAX concentration and intrinsic apoptosis are poorly understood. Exogenous GFP-murine Bax fusion constructs were transfected into BAX-deficient HCT116 cells. To titrate the expression of the fusion protein, GFP-BAX was cloned into a tetracycline sensitive expression cassette and cotransfected with a plasmid expressing the rtTA transcription factor into HCT116 BAX-/- cells. Linear expression of the fusion gene was induced with doxycycline and monitored by quantitative PCR and immunoblotting. Cell death was assayed by DAPI staining cells after exposure to indomethacin, and scoring nuclei for condensed chromatin and fragmented nuclei. HCT116 BAX-/- cells were resistant to indomethacin, but susceptibility could be recovered in cells expressing a GFP-BAX fusion protein. Titration of GFP-BAX expression revealed that the concentration of BAX required to induce a saturating apoptosis response from baseline, was rapidly achieved. Increased levels of GFP-BAX were unable to stimulate higher levels of cell death. Examination of GFP-BAX distribution before and after indomethacin treatment indicated that BAX protein did not form aggregates when present at sub-lethal concentrations. Within the limitations of this experimental system, BAX-dependent apoptosis in HCT116 cells exhibits an all-or-none response depending on the level of BAX protein present. The lack of BAX aggregation at sub-saturation levels suggests that the

Fusion is urgent needed for the developing countries

International Nuclear Information System (INIS)

Li Jiangang

2005-01-01

Energy is a global problem, as it is central to economic development, climate and environment, and international stability and sustainability. Energy need is expected to double in 40 years and an even larger increase is needed to lift the world out of poverty. 80% of world's energy is generated by burning fossil fuels, which is driving climate change and generating pollution. China will grow up to be a moderate developed country in 2050. The coal-centred energy structure will remain until 2050. Annual Energy Consumption per person will increase from near 1 TCE to no less than 3 TCE ( at present time, US: 11.5 TCE; West Europe: 5.6 TCE; Japan: 5.1 TCE) Estimated Energy Demand: increasing from near 1B TCE to over 4B TCE within next 3-4 decades. To realize the long-term sustainable development, it is necessary for China to explore reliable ways and develop thousands of GW non- fossil fuel power. The fission energy is a transit solution. To build hundreds of GW Fission Nuclear Power Plants in China - social problems, safety and environmental concerns, technical difficulties should be solved in near future. It is crucial and urgent for China to realize the controlled Nuclear Fusion Energy for our long-term development in the future as early as possible. Fusion shows environmentally responsible and intrinsically safe, the supplies of fuel are essentially limitless. JET has produced 16MW of fusion power and shown that fusion can be mastered on earth. Fusion has a long and successful history of international collaboration with obvious benefits to all partners for peaceful purpose. ITER is a device for us to bring the Sun to earth for the first time in the history. A properly organised and funded fusion development programme could lead to a proto-type fusion power plant to generate electricity to the grid within about 30 years (ITER+IFMIF). For developing countries, such as China and India, fusion is one of the very few options for large-scale sustainable energy generation

Fusion technology development: role of fusion facility upgrades and fission test reactors

International Nuclear Information System (INIS)

Hsu, P.Y.; Deis, G.A.; Longhurst, G.R.; Miller, L.G.; Schmunk, R.E.

1983-01-01

The near term national fusion program is unlikely to follow the aggressive logic of the Fusion Engineering Act of 1980. Faced with level budgets, a large, new fusion facility with an engineering thrust is unlikely in the near future. Within the fusion community the idea of upgrading the existing machines (TFTR, MFTF-B) is being considered to partially mitigate the lack of a design data base to ready the nation to launch an aggressive, mission-oriented fusion program with the goal of power production. This paper examines the cost/benefit issues of using fusion upgrades to develop the technology data base which will be required to support the design and construction of the next generation of fusion machines. The extent of usefulness of the nation's fission test reactors will be examined vis-a-vis the mission of the fusion upgrades. The authors show that while fission neutrons will provide a useful test environment in terms of bulk heating and tritium breeding on a submodule scale, they can play only a supporting role in designing the integrated whole modules and systems to be used in a nuclear fusion machine

Fusion technology development: role of fusion facility upgrades and fission test reactors

International Nuclear Information System (INIS)

Hsu, P.Y.; Deis, G.A.; Miller, L.G.; Longhurst, G.R.; Schmunk, R.E.

1983-01-01

The near term national fusion program is unlikely to follow the aggressive logic of the Fusion Engineering Act of 1980. Faced with level budgets, a large, new fusion facility with an engineering thrust is unlikely in the near future. Within the fusion community the idea of upgrading the existing machines (TFTR, MFTF-B) is being considered to partially mitigate the lack of a design data base to ready the nation to launch an aggressive, mission-oriented fusion program with the goal of power production. This paper examines the cost/benefit issues of using fusion upgrades to develop the technology data base which will be required to support the design and construction of the next generation of fusion machines. The extent of usefulness of the nation's fission test reactors will be examined vis-a-vis the mission of the fusion upgrades. We will show that while fission neutrons will provide a useful test environment in terms of bulk heating and tritium breeding on a submodule scale, they can play only a supporting role in designing the integrated whole modules and systems to be used in a nuclear fusion machine

Cold nuclear fusion

Energy Technology Data Exchange (ETDEWEB)

Tsyganov, E.N., E-mail: edward.tsyganov@coldfusion-power.com [Cold Fusion Power, International (United States); Bavizhev, M.D. [LLC “Radium”, Moscow (Russian Federation); Buryakov, M.G. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Dabagov, S.B. [RAS P.N. Lebedev Physical Institute, Leninsky pr. 53, 119991 Moscow (Russian Federation); National Research Nuclear University MEPhI, Kashirskoe shosse 31, 115409 Moscow (Russian Federation); Golovatyuk, V.M.; Lobastov, S.P. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation)

2015-07-15

If target deuterium atoms were implanted in a metal crystal in accelerator experiments, a sharp increase in the probability of DD-fusion reaction was clearly observed when compared with the reaction’s theoretical value. The electronic screening potential, which for a collision of free deuterium atoms is about 27 eV, reached 300–700 eV in the case of the DD-fusion in metallic crystals. These data leads to the conclusion that a ban must exist for deuterium atoms to be in the ground state 1s in a niche filled with free conduction electrons. At the same time, the state 2p whose energy level is only 10 eV above that of state 1s is allowed in these conditions. With anisotropy of 2p, 3p or above orbitals, their spatial positions are strictly determined in the lattice coordinate system. When filling out the same potential niches with two deuterium atoms in the states 2p, 3p or higher, the nuclei of these atoms can be permanently positioned without creating much Coulomb repulsion at a very short distance from each other. In this case, the transparency of the potential barrier increases dramatically compared to the ground state 1s for these atoms. The probability of the deuterium nuclei penetrating the Coulomb barrier by zero quantum vibration of the DD-system also increases dramatically. The so-called cold nuclear DD-fusion for a number of years was registered in many experiments, however, was still rejected by mainstream science for allegedly having no consistent scientific explanation. Finally, it received the validation. Below, we outline the concept of this explanation and give the necessary calculations. This paper also considers the further destiny of the formed intermediate state of {sup 4}He{sup ∗}.

Fusion propulsion systems

International Nuclear Information System (INIS)

Haloulakos, V.E.; Bourque, R.F.

1989-01-01

The continuing and expanding national efforts in both the military and commercial sectors for exploration and utilization of space will require launch, assembly in space, and orbital transfer of large payloads. The currently available delivery systems, utilizing various forms of chemical propulsion, do not have the payload capacity to fulfill the planned missions. National planning documents such as Air Force Project Forecast II and the National Commission on Space Report to the President contain numerous missions and payload delivery schedules that are beyond the present capabilities of the available systems, such as the Space Shuttle and the Expendable Launch Vehicles (ELVs). The need, therefore, is very pressing to design, develop, and deploy propulsion systems that offer a quantum level increase in delivered performance. One such potential system is fusion propulsion. This paper summarizes the result of an Air Force Astronautics Laboratory (AFAL) sponsored study of fusion propulsion conducted by the McDonnell Douglas Astronautics Company (MDAC), and its subcontractor General Atomics This study explored the potential of fusion propulsion for Air Force missions. Fusion fuels and existing confinement concepts were evaluated according to elaborate criteria. Two fuels, deuterium-tritium and deuterium-helium 3 (D- 3 He) were considered worthy of further consideration. D- 3 He was selected as the most attractive for this Air Force study. The colliding translating compact torus confinement concept was evaluated in depth and found to possibly possess the low mass and compactness required. Another possible concept is inertial confinement with the propellant surrounding the target. 5 refs., 5 figs., 8 tabs

The Canadian Fusion Fuels Technology Project

International Nuclear Information System (INIS)

Dautovich, D.P.; Gierszewski, P.J.; Wong, K.Y.; Stasko, R.R.; Burnham, C.D.

1987-04-01

The Canadian Fusion Fuels Technology Project (CFFTP) is a national project whose aim is to develop capability in tritium and robotics technologies for application to international fusion development programs. Activities over the first five years have brought substantial interaction with the world's leading projects such as Tokamak Fusion Test Reactor (TFTR), the Joint European Torus (JET), and the Next European Torus (NET), Canadian R and D and engineering services, and hardware are in demand as these major projects prepare for tritium operation leading to the demonstration of energy breakeven around 1990. Global planning is underway for the next generation ignition experiment. It is anticipated this will provide increased opportunity for CFFTP and its contractors among industry, universities and governmental laboratories

Building the US National Fusion Grid: results from the National Fusion Collaboratory Project

International Nuclear Information System (INIS)

Schissel, D.P.; Burruss, J.R.; Finkelstein, A.; Flanagan, S.M.; Foster, I.T.; Fredian, T.W.; Greenwald, M.J.; Johnson, C.R.; Keahey, K.; Klasky, S.A.; Li, K.; McCune, D.C.; Papka, M.; Peng, Q.; Randerson, L.; Sanderson, A.; Stillerman, J.; Stevens, R.; Thompson, M.R.; Wallace, G.

2004-01-01

The US National Fusion Collaboratory Project is developing a persistent infrastructure to enable scientific collaboration for all aspects of magnetic fusion research. The project is creating a robust, user-friendly collaborative software environment and making it available to more than 1000 fusion scientists in 40 institutions who perform magnetic fusion research in the United States. In particular, the project is developing and deploying a national Fusion Energy Sciences Grid (FusionGrid) that is a system for secure sharing of computation, visualization, and data resources over the Internet. The FusionGrid goal is to allow scientists at remote sites to fully participate in experimental and computational activities as if they were working at a common site thereby creating a virtual organization of the US fusion community. The project is funded by the USDOE Office of Science, Scientific Discovery through Advanced Computing (SciDAC) Program and unites fusion and computer science researchers to directly address these challenges

Transforaminal lumbar interbody fusion versus posterolateral fusion in degenerative lumbar spondylosis

Science.gov (United States)

Zhang, Bin-Fei; Ge, Chao-Yuan; Zheng, Bo-Long; Hao, Ding-Jun

2016-01-01

Abstract Objective: The aim of the study was to evaluate the efficacy and safety of transforaminal lumbar interbody fusion (TLIF) versus posterolateral fusion (PLF) in degenerative lumbar spondylosis. Methods: A systematic literature review was performed to obtain randomized controlled trials (RCTs) and observational studies (OSs) of TLIF and PLF for degenerative lumbar spondylosis. Trials performed before November 2015 were retrieved from the Medline, EMBASE, Cochrane library, and Chinese databases. Data extraction and quality evaluation of the trials were performed independently by 2 investigators. A meta-analysis was performed using STATA version 12.0. Results: Two RCTs and 5 OSs of 630 patients were included. Of these subjects, 325 were in the TLIF and 305 were in the PLF group. Results showed that TLIF did not increase the fusion rate based on RCTs (relative risk [RR] = 1.06; 95% confidence interval [CI]: 0.95–1.18; P = 0.321), but increased it based on OSs (RR = 1.14; 95% CI: 1.07–1.23; P = 0.000) and overall (RR = 1.11; 95% CI: 1.05–1.18; P = 0.001) as compared with PLF. TLIF was able to improve the clinical outcomes based on 1 RCT (RR = 1.33; 95% CI: 1.11–1.59, P = 0.002) and overall (RR = 1.19; 95% CI: 1.07–1.33; P = 0.001), but not based on OSs (RR = 1.11; 95% CI: 0.97–1.27; P = 0.129) as compared with PLF. There were no differences between TLIF and PLF in terms of visual analogue scale, Oswestry Disability Index, reoperation, complications, duration of surgical procedure, blood loss, and hospitalization. Conclusions: In conclusion, evidence is not sufficient to support that TLIF provides higher fusion rate than PLF, and this poor evidence indicates that TLIF might improve only clinical outcomes. Higher quality, multicenter RCTs are needed to better define the role of TLIF and PLF. PMID:27749558

Synthesis and decay process of superheavy nuclei with Z=119-122 via hot-fusion reactions

Energy Technology Data Exchange (ETDEWEB)

Ghahramany, N.; Ansari, A. [Shiraz University, Department of Physics and Biruni Observatory, College of Science, Shiraz (Iran, Islamic Republic of)

2016-09-15

In this research article attempts have been made to calculate the superheavy-nuclei synthesis characteristics including, the potential energy parameters, fusion probability, fusion and evaporation residue (ER) cross sections as well as, decay properties of compound nucleus and the residue nuclei formation probability for elements with Z=119-122 by using the hot-fusion reactions. It is concluded that, although a selection of double magic projectiles such as {sup 48}Ca with high binding energy, simplifies the calculations significantly due to spherical symmetric shape of the projectile, resulting in high evaporation residue cross section, unfortunately, nuclei with Z > 98 do not exist in quantities sufficient for constructing targets for the hot-fusion reactions. Therefore, practically our selection is fusion reactions with titanium projectile because the mass production of target nuclei for experimental purposes is more feasible. Based upon our findings, it is necessary, for new superheavy-nuclei production with Z > 119, to use neutron-rich projectiles and target nuclei. Finally, the maximal evaporation residue cross sections for the synthesis of superheavy elements with Z=119-122 have been calculated and compared with the previously founded ones in the literature. (orig.)

Preventing droplet deformation during dielectrophoretic centering of a compound emulsion droplet

Science.gov (United States)

Randall, Greg; Blue, Brent

2012-11-01

Compound droplets, or droplets-within-droplets, are traditionally key components in applications ranging from drug delivery to the food industry. Presently, millimeter-sized compound droplets are precursors for shell targets in inertial fusion energy work. However, a key constraint in target fabrication is a uniform shell wall thickness, which in turn requires a centered core droplet in the compound droplet precursor. Previously, Bei et al. (2009, 2010) have shown that compound droplets could be centered in a static fluid using an electric field of 0.7 kV/cm at 20 MHz. Randall et al. (2012) developed a process to center the core of a moving compound droplet, though the ~kV/cm field induced small (fluid mechanics and interfacial rheology perspective and we discuss the effective interfacial charge from an emulsifier and its impact on centering. Work funded by General Atomics Internal R&D.

Fusion fuel and renewables

International Nuclear Information System (INIS)

Entler, Slavomir

2015-01-01

It is shown that fusion fuel meets all aspects applied when defining renewables. A table of definitions of renewables is presented. The sections of the paper are as follows: An industrial renewable source; Nuclear fusion; Current situation in research; Definitions of renewable sources; Energy concept of nuclear fusion; Fusion fuel; Natural energy flow; Environmental impacts; Fusion fuel assessment; Sustainable power; and Energy mix from renewables. (P.A.)

2,4-Dichlorophenoxyacetic acid increases reserve compounds and ...

African Journals Online (AJOL)

The aim of this study was to develop an in vitro culture system for Senna spectabilis and to quantify contents of storage compounds and spectaline in induced calli in relation to exogenous auxin. Explants (cotyledon, hypocotyl, epicotyl, and leaf) were cultured on MS medium containing different concentrations of 2 ...

Towards nuclear fusion reactors

International Nuclear Information System (INIS)

1993-11-01

The results of nuclear fusion researches in JAERI are summarized. In this report, following themes are collected: the concept of fusion reactor (including ITER), fusion reactor safety, plasma confinement, fusion reactor equipment, and so on. Includes glossary. (J.P.N.)

MR tomography in the assessment of functional stability of posterolateral lumbar fusions

International Nuclear Information System (INIS)

Lang, P.; Genant, H.K.; Chafetz, N.; Steiger, P.; Stoller, D.; California Univ., San Francisco

1987-01-01

MR tomography was used to assess functional lumbar stability in 30 patients with posterolateral fusions. The vertebral bodies of 9 of the 12 patients with unstable lumbar fusions presented with areas of decreased signal intensity on T 1 - and intermediately weighted images, which increased on T 2 -weighting. The vertebrae of 15 of the 18 patients with stable fusions demonstrated zones of increased signal intensity on T 1 - and intermediately weighted images, which were less intense or invisible on T 2 -weighting. Surgical correlation was available in 11 of the 30 patients studied. Hyperemia and inflammation appear to be responsible for the abnormal signal intensities in the patients with stable fusions, whereas an increase in adipose marrow due to decreased biomechanical stress is thought to account for the atypical signal intensities in the vertebral bodies of the patients with stable fusions. MR tomography seems to be a potential method for evaluating functional lumbar fusion stability. MR tomography may be particularly helpful in those patients with multiple back surgeries and possible instability, recurrent disc herniation, or post-operative fibrosis. MR is recommended in the patient, who appears clinically unstable, whose radiographs and CT, however, do not demonstrate fusion failure. (orig.) [de

Nuclear fusion: Pursuing the Soft [Symposium on fusion technology] option

International Nuclear Information System (INIS)

Kenward, M.

1991-01-01

Fusion research has come a long way since the fusion community held the first Symposium on fusion technology (Soft) in Britain 30 years ago. Some of the recent achievements of the Jet project are reported from this year's symposium, the 16th in the series, held in London at the beginning of September. (author)

Membrane fusion and inverted phases

International Nuclear Information System (INIS)

Ellens, H.; Siegel, D.P.; Alford, D.; Yeagle, P.L.; Boni, L.; Lis, L.J.; Quinn, P.J.; Bentz, J.

1989-01-01

We have found a correlation between liposome fusion kinetics and lipid phase behavior for several inverted phase forming lipids. N-Methylated dioleoylphosphatidylethanolamine (DOPE-Me), or mixtures of dioleoylphosphatidylethanolamine (DOPE) and dioleoylphosphatidylcholine (DOPC), will form an inverted hexagonal phase (HII) at high temperatures (above TH), a lamellar phase (L alpha) at low temperatures, and an isotropic/inverted cubic phase at intermediate temperatures, which is defined by the appearance of narrow isotropic 31 P NMR resonances. The phase behavior has been verified by using high-sensitivity DSC, 31 P NMR, freeze-fracture electron microscopy, and X-ray diffraction. The temperature range over which the narrow isotropic resonances occur is defined as delta TI, and the range ends at TH. Extruded liposomes (approximately 0.2 microns in diameter) composed of these lipids show fusion and leakage kinetics which are strongly correlated with the temperatures of these phase transitions. At temperatures below delta TI, where the lipid phase is L alpha, there is little or no fusion, i.e., mixing of aqueous contents, or leakage. However, as the temperature reaches delta TI, there is a rapid increase in both fusion and leakage rates. At temperatures above TH, the liposomes show aggregation-dependent lysis, as the rapid formation of HII phase precursors disrupts the membranes. We show that the correspondence between the fusion and leakage kinetics and the observed phase behavior is easily rationalized in terms of a recent kinetic theory of L alpha/inverted phase transitions. In particular, it is likely that membrane fusion and the L alpha/inverted cubic phase transition proceed via a common set of intermembrane intermediates

Feature-Fusion Guidelines for Image-Based Multi-Modal Biometric Fusion

Directory of Open Access Journals (Sweden)

Dane Brown

2017-07-01

Full Text Available The feature level, unlike the match score level, lacks multi-modal fusion guidelines. This work demonstrates a new approach for improved image-based biometric feature-fusion. The approach extracts and combines the face, fingerprint and palmprint at the feature level for improved human identification accuracy. Feature-fusion guidelines, proposed in our recent work, are extended by adding a new face segmentation method and the support vector machine classifier. The new face segmentation method improves the face identification equal error rate (EER by 10%. The support vector machine classifier combined with the new feature selection approach, proposed in our recent work, outperforms other classifiers when using a single training sample. Feature-fusion guidelines take the form of strengths and weaknesses as observed in the applied feature processing modules during preliminary experiments. The guidelines are used to implement an effective biometric fusion system at the feature level, using a novel feature-fusion methodology, reducing the EER of two groups of three datasets namely: SDUMLA face, SDUMLA fingerprint and IITD palmprint; MUCT Face, MCYT Fingerprint and CASIA Palmprint.

Examination of a proposed phonon-coupling mechanism for cold fusion

International Nuclear Information System (INIS)

Crawford, O.H.

1992-01-01

In this paper the proposed nuclear energy in an atomic lattice (NEAL) mechanism for nuclear fusion in a cathode during electrolysis of D 2 O is examined. In this mechanism, coupled harmonic motion of deuterons is supposed to lead to a reduction in the width of the Coulomb barrier for proton-deuteron (p-d) fusion in palladium, thereby substantially increasing the fusion rate. Instead, it is argued that deuteron-deuteron coupling does not have an important effect and that interaction with phonons does not enhance the p-d fusion rate

The fusion-fission hybrid

International Nuclear Information System (INIS)

Teller, E.

1985-01-01

As the history of the development of fusion energy shows, a sustained controlled fusion reaction is much more difficult to produce than rapid uncontrolled release of fusion energy. Currently, the ''magnetic bottle'' technique shows sufficient progress that it might applied for the commercial fuel production of /sup 233/U, suitable for use in fission reactors, by developing a fusion-fission hybrid. Such a device would consist of a fusion chamber core surrounded by a region containing cladded uranium pellets cooled by helium, with lithium salts also present to produce tritium to refuel the fusion process. Successful development of this hybrid might be possible within 10 y, and would provide both experience and funds for further development of controlled fusion energy

Fusion power

International Nuclear Information System (INIS)

Hancox, R.

1981-01-01

The principles of fusion power, and its advantages and disadvantages, are outlined. Present research programmes and future plans directed towards the development of a fusion power reactor, are summarized. (U.K.)

[Mechanical studies of lumbar interbody fusion implants].

Science.gov (United States)

Bader, R J; Steinhauser, E; Rechl, H; Mittelmeier, W; Bertagnoli, R; Gradinger, R

2002-05-01

In addition to autogenous or allogeneic bone grafts, fusion cages composed of metal or plastic are being used increasingly as spacers for interbody fusion of spinal segments. The goal of this study was the mechanical testing of carbon fiber reinforced plastic (CFRP) fusion cages used for anterior lumbar interbody fusion. With a special testing device according to American Society for Testing and Materials (ASTM) standards, the mechanical properties of the implants were determined under four different loading conditions. The implants (UNION cages, Medtronic Sofamor Danek) provide sufficient axial compression, shear, and torsional strength of the implant body. Ultimate axial compression load of the fins is less than the physiological compression loads at the lumbar spine. Therefore by means of an appropriate surgical technique parallel grooves have to be reamed into the endplates of the vertebral bodies according to the fin geometry. Thereby axial compression forces affect the implants body and the fins are protected from damaging loading. Using a supplementary anterior or posterior instrumentation, in vivo failure of the fins as a result of physiological shear and torsional spinal loads is unlikely. Due to specific complications related to autogenous or allogeneic bone grafts, fusion cages made of metal or carbon fiber reinforced plastic are an important alternative implant in interbody fusion.

Microstructure–hardness relationship in the fusion zone of TRIP steel welds

International Nuclear Information System (INIS)

Nayak, S.S.; Baltazar Hernandez, V.H.; Okita, Y.; Zhou, Y.

2012-01-01

Highlights: ► Fusion zone of TRIP steels in resistance spot welding was analyzed. ► Transmission electron microscopy (TEM) was used for characterizing microstructure. ► Fusion zone microstructure was found to depend on the chemistry. ► Hardness values were in accordance with the microstructural constituents in the fusion zone. - Abstract: Fusion zone of three TRIP steels, categorized as AT: C–Mn–Al, AST: C–Mn–Al–Si and ST: C–Mn–Si, in resistance spot welding was characterized with respect to microstructure, phase analysis, and hardness. The fusion zone microstructure was found to depend on chemistry: (i) AT steel contained ferrite phase surrounded by bainite and martensite regions, (ii) AST steel showed a bainite structures along with martensite laths and interlath retained austenite, whereas (iii) ST steel constituted single phase martensite laths with interlath austenite. X-ray diffraction study indicated that retained austenite fraction in the fusion zone increases with increase in Si content in it. The AST fusion zone hardness lies between those of the AT and ST steels; the ST fusion zone hardness was higher than that of AT steel because of the single phase martensite microstructure. Comparison of fusion zone microstructure and hardness to earlier study on laser welding of the TRIP steels with similar chemistries revealed that higher cooling rate in resistance spot welding led to higher fusion zone hardness compared to laser welding; which was attributed either to decrease in softer ferrite phase (AT steel) in the microstructure or refinement of martensite laths (ST steel).

Vaporization, fusion and sublimation enthalpies of the dicarboxylic acids from C4 to C14 and C16

International Nuclear Information System (INIS)

Roux, Maria Victoria; Temprado, Manuel; Chickos, James S.

2005-01-01

The fusion enthalpies of the series butanedioic acid through to tetradecanedioic acid and hexadecanedioic acids have been measured by DSC. In addition to fusion, a number of solid-solid phase transitions have also been detected in these diacids. The vaporization enthalpies of these compounds have been measured by correlation gas chromatography using the vaporization enthalpies of butanedioic, hexanedioic and decanedioic acids as standards. The vaporization enthalpies of the diacids from C 4 to C 10 correlated linearly with the number of methylene groups present. Above C 10 , the vaporization enthalpies of C 11 -C 14 and C 16 begin to deviate from linearity. The vaporization enthalpies for these compounds are dependent on the temperature of the GC column used. Similar departure from linearity has also been observed previously in the sublimation enthalpies for these compounds. The results are discussed in terms of formation of a cyclic intramolecular hydrogen bonded network in the gas phase similar to the bimolecular association observed in smaller mono-carboxylic acids at ambient temperatures

Spatial focalization of pheromone/MAPK signaling triggers commitment to cell–cell fusion

Science.gov (United States)

Merlini, Laura

2016-01-01

Cell fusion is universal in eukaryotes for fertilization and development, but what signals this process is unknown. Here, we show in Schizosaccharomyces pombe that fusion does not require a dedicated signal but is triggered by spatial focalization of the same pheromone–GPCR (G-protein-coupled receptor)–MAPK signaling cascade that drives earlier mating events. Autocrine cells expressing the receptor for their own pheromone trigger fusion attempts independently of cell–cell contact by concentrating pheromone release at the fusion focus, a dynamic actin aster underlying the secretion of cell wall hydrolases. Pheromone receptor and MAPK cascade are similarly enriched at the fusion focus, concomitant with fusion commitment in wild-type mating pairs. This focalization promotes cell fusion by immobilizing the fusion focus, thus driving local cell wall dissolution. We propose that fusion commitment is imposed by a local increase in MAPK concentration at the fusion focus, driven by a positive feedback between fusion focus formation and focalization of pheromone release and perception. PMID:27798845

Semi empirical model for astrophysical nuclear fusion reactions of 1≤Z≤15

International Nuclear Information System (INIS)

Manjunatha, H.C.; Seenappa, L.; Sridhar, K.N.

2017-01-01

The fusion reaction is one of the most important reactions in the stellar evolution. Due to the complicated reaction mechanism of fusion, there is great uncertainty in the reaction rate which limits our understanding of various stellar objects. Low z elements are formed through many fusion reactions such as "4He+"1"2C→"1"6O, "1"2C+"1"2C→"2"0Ne+"4He, "1"2C+"1"2C→"2"3Na, "1"2C+"1"2C→"2"3Mg, "1"6O+"1"6O→"2"8Si+"4He, "1"2C+"1H→"1"3N and "1"3C+"4He→"1"6O. A detail study is required on Coulomb and nuclear interaction in formation of low Z elements in stars through fusion reactions. For astrophysics, the important energy range extends from 1 MeV to 3 MeV in the center of mass frame, which is only partially covered by experiments. In the present work, we have studied the basic fusion parameters such as barrier heights (V_B), positions (R_B), curvature of the inverted parabola (ħω_1) for fusion barrier, cross section and compound nucleus formation probability (P_C_N) and fusion process in the low Z element (1≤Z≤15) formation process. For each isotope, we have studied all possible projectile-target combinations. We have also studied the astrophysical S(E) factor for these reactions. Based on this study, we have formulated the semi empirical relations for barrier heights (V_B), positions (R_B), curvature of the inverted parabola and hence for the fusion cross section and astrophysical S(E) factor. The values produced by the present model compared with the experiments and data available in the literature. (author)

Recycling fusion materials

International Nuclear Information System (INIS)

Ooms, L.

2005-01-01

The inherent safety and environmental advantages of fusion power in comparison with other energy sources play an important role in the public acceptance. No waste burden for future generations is therefore one of the main arguments to decide for fusion power. The waste issue has thus been studied in several documents and the final conclusion of which it is stated that there is no permanent disposal waste needed if recycling is applied. But recycling of fusion reactor materials is far to be obvious regarding mostly the very high specific activity of the materials to be handled, the types of materials and the presence of tritium. The main objective of research performed by SCK-CEN is to study the possible ways of recycling fusion materials and analyse the challenges of the materials management from fusion reactors, based on current practices used in fission reactors and the requirements for the manufacture of fusion equipment

Sensor fusion for intelligent alarm analysis

International Nuclear Information System (INIS)

Nelson, C.L.; Fitzgerald, D.S.

1996-01-01

The purpose of an intelligent alarm analysis system is to provide complete and manageable information to a central alarm station operator by applying alarm processing and fusion techniques to sensor information. This paper discusses the sensor fusion approach taken to perform intelligent alarm analysis for the Advanced Exterior Sensor (AES). The AES is an intrusion detection and assessment system designed for wide-area coverage, quick deployment, low false/nuisance alarm operation, and immediate visual assessment. It combines three sensor technologies (visible, infrared, and millimeter wave radar) collocated on a compact and portable remote sensor module. The remote sensor module rotates at a rate of 1 revolution per second to detect and track motion and provide assessment in a continuous 360 degree field-of-regard. Sensor fusion techniques are used to correlate and integrate the track data from these three sensors into a single track for operator observation. Additional inputs to the fusion process include environmental data, knowledge of sensor performance under certain weather conditions, sensor priority, and recent operator feedback. A confidence value is assigned to the track as a result of the fusion process. This helps to reduce nuisance alarms and to increase operator confidence in the system while reducing the workload of the operator

Return to Golf After Lumbar Fusion.

Science.gov (United States)

Shifflett, Grant D; Hellman, Michael D; Louie, Philip K; Mikhail, Christopher; Park, Kevin U; Phillips, Frank M

Spinal fusion surgery is being increasingly performed, yet few studies have focused on return to recreational sports after lumbar fusion and none have specifically analyzed return to golf. Most golfers successfully return to sport after lumbar fusion surgery. Case series. Level 4. All patients who underwent 1- or 2-level primary lumbar fusion surgery for degenerative pathologies performed by a single surgeon between January 2008 and October 2012 and had at least 1-year follow-up were included. Patients completed a specifically designed golf survey. Surveys were mailed, given during follow-up clinic, or answered during telephone contact. A total of 353 patients met the inclusion and exclusion criteria, with 200 responses (57%) to the questionnaire producing 34 golfers. The average age of golfers was 57 years (range, 32-79 years). In 79% of golfers, preoperative back and/or leg pain significantly affected their ability to play golf. Within 1 year from surgery, 65% of patients returned to practice and 52% returned to course play. Only 29% of patients stated that continued back/leg pain limited their play. Twenty-five patients (77%) were able to play the same amount of golf or more than before fusion surgery. Of those providing handicaps, 12 (80%) reported the same or an improved handicap. More than 50% of golfers return to on-course play within 1 year of lumbar fusion surgery. The majority of golfers can return to preoperative levels in terms of performance (handicap) and frequency of play. This investigation offers insight into when golfers return to sport after lumbar fusion surgery and provides surgeons with information to set realistic expectations postoperatively.

A search for parameters of universal sub-barrier fusion excitation function

Energy Technology Data Exchange (ETDEWEB)

Qu, W.W. [Medical College of Soochow University, School of Radiation Medicine and Protection, Soochow (China); Zhang, G.L. [Beihang University, School of Physics and Nuclear Energy Engineering, Beijing (China); Wolski, R. [Henryk Niewodniczanski Institute of Nuclear Physics PAS, Cracow (Poland)

2016-11-15

Many fusion experimental data have been analyzed in terms of a simple universal function which could be used for predictions of fusion cross section below the barrier for arbitrary systems. Sub-barrier fusions based on the concept of Q -fusion value dependence were studied. It is attempted to parameterize the energy-reduced fusion excitation functions around the Coulomb barriers by an analytical phenomenological function. It was found that the speed of driving nuclei towards fusion is faster with the increase of mass asymmetry of colliding systems and those systems with a large difference of the ratio of neutrons to protons. However, a general trend with respect to total mass has not been observed. An exposition of more qualitative conclusions is hindered by apparent inconsistencies of measured fusion cross sections. (orig.)

Nuclear Fusion prize laudation Nuclear Fusion prize laudation

Science.gov (United States)

Burkart, W.

2011-01-01

Clean energy in abundance will be of critical importance to the pursuit of world peace and development. As part of the IAEA's activities to facilitate the dissemination of fusion related science and technology, the journal Nuclear Fusion is intended to contribute to the realization of such energy from fusion. In 2010, we celebrated the 50th anniversary of the IAEA journal. The excellence of research published in the journal is attested to by its high citation index. The IAEA recognizes excellence by means of an annual prize awarded to the authors of papers judged to have made the greatest impact. On the occasion of the 2010 IAEA Fusion Energy Conference in Daejeon, Republic of Korea at the welcome dinner hosted by the city of Daejeon, we celebrated the achievements of the 2009 and 2010 Nuclear Fusion prize winners. Steve Sabbagh, from the Department of Applied Physics and Applied Mathematics, Columbia University, New York is the winner of the 2009 award for his paper: 'Resistive wall stabilized operation in rotating high beta NSTX plasmas' [1]. This is a landmark paper which reports record parameters of beta in a large spherical torus plasma and presents a thorough investigation of the physics of resistive wall mode (RWM) instability. The paper makes a significant contribution to the critical topic of RWM stabilization. John Rice, from the Plasma Science and Fusion Center, MIT, Cambridge is the winner of the 2010 award for his paper: 'Inter-machine comparison of intrinsic toroidal rotation in tokamaks' [2]. The 2010 award is for a seminal paper that analyzes results across a range of machines in order to develop a universal scaling that can be used to predict intrinsic rotation. This paper has already triggered a wealth of experimental and theoretical work. I congratulate both authors and their colleagues on these exceptional papers. W. Burkart Deputy Director General Department of Nuclear Sciences and Applications International Atomic Energy Agency, Vienna

Demountable toroidal fusion core facility for physics optimization and fusion engineering

International Nuclear Information System (INIS)

Bogart, S.L.; Wagner, C.E.; Krall, N.A.; Dalessandro, J.A.; Weggel, C.F.; Lund, K.O.; Sedehi, S.

1986-01-01

Following a successful compact ignition tokamak (CIT) experiment, a fusion facility will be required for physics optimization (POF) and fusion engineering research (FERF). The POF will address issues such as high-beta operation, current drive, impurity control, and will test geometric and configurational variations such as the spherical torus or the reversed-field pinch (RFP). The FERF will be designed to accumulate rapidly a large neutron dose in prototypical fusion subsystems exposed to radiation. Both facilities will require low-cost replacement cores and rapid replacement times. The Demountable Toroidal Fusion Core (DTFC) facility is designed to fulfill these requirements. It would be a cost-effective stepping stone between the CIT and a demonstration fusion reactor

Mirror fusion test facility plasma diagnostics system

International Nuclear Information System (INIS)

Thomas, S.R. Jr.; Coffield, F.E.; Davis, G.E.; Felker, B.

1979-01-01

During the past 25 years, experiments with several magnetic mirror machines were performed as part of the Magnetic Fusion Energy (MFE) Program at LLL. The latest MFE experiment, the Mirror Fusion Test Facility (MFTF), builds on the advances of earlier machines in initiating, stabilizing, heating, and sustaining plasmas formed with deuterium. The goals of this machine are to increase ion and electron temperatures and show a corresponding increase in containment time, to test theoretical scaling laws of plasma instabilities with increased physical dimensions, and to sustain high-beta plasmas for times that are long compared to the energy containment time. This paper describes the diagnostic system being developed to characterize these plasma parameters

Computing for magnetic fusion energy research: An updated vision

International Nuclear Information System (INIS)

Henline, P.; Giarrusso, J.; Davis, S.; Casper, T.

1993-01-01

This Fusion Computing Council perspective is written to present the primary of the fusion computing community at the time of publication of the report necessarily as a summary of the information contained in the individual sections. These concerns reflect FCC discussions during final review of contributions from the various working groups and portray our latest information. This report itself should be considered as dynamic, requiring periodic updating in an attempt to track rapid evolution of the computer industry relevant to requirements for magnetic fusion research. The most significant common concern among the Fusion Computing Council working groups is networking capability. All groups see an increasing need for network services due to the use of workstations, distributed computing environments, increased use of graphic services, X-window usage, remote experimental collaborations, remote data access for specific projects and other collaborations. Other areas of concern include support for workstations, enhanced infrastructure to support collaborations, the User Service Centers, NERSC and future massively parallel computers, and FCC sponsored workshops

Increasing risk of compound flooding from storm surge and rainfall for major US coastal cities

Science.gov (United States)

Wahl, Thomas; Jain, Shaleen; Bender, Jens; Meyers, Steven; Luther, Mark

2016-04-01

Flood risk is a well-known facet of natural hazards along the US coastline where nearly 40% of the population resides in coastal counties. Given the heavy reliance on the coastal zone for natural resources and economic activity, flood preparedness and safety is a key element of long-term resilience. A clear understanding of the various flood types and changes in the frequency of their occurrence is critical towards reliable estimates of vulnerability and potential impacts in the near-term as well as into the future. When the two main flood drivers for coastal areas storm surge and heavy precipitation occur in tandem the potential for significant flooding is much greater than from either in isolation. Exploring the probability of these 'compound events' and understanding the processes driving them is essential to mitigate the associated high impact risks. For the contiguous US the likelihood of the joint occurrence of the two phenomena is largely unknown. Here we show - using storm surge and precipitation records spanning the last century - that the risk of compound flooding is higher for the US east and Gulf coasts, relative to the west coast. We also show that the number of compound events has increased significantly over the last century along large coastline stretches including many of the major coastal cities. For New York City - as an example - this increase is attributed to a shift towards storm surge weather patterns also favouring high precipitation. Preliminary analyses reveal that these synoptic scale changes are closely linked to large scale and low frequency climate variations. Our results demonstrate the importance of assessing the risk of compound flooding within the design process of coastal and urban infrastructure in a non-stationary framework and to explore the potential effects of climate change on these high impact events.

Some fusion perspectives

International Nuclear Information System (INIS)

McNally, J.R. Jr.

1977-01-01

Some of the concepts of nuclear fusion reactions, advanced fusion fuels, environmental impacts, etc., are explored using the following general outline: I. Principles of Fusion (Nuclear Fuels and Reactions, Lawson Condition, n tau vs T, Nuclear Burn Characteristics); II. Magnetic Mirror Possibilities (the Ion Layer and Electron Layer, Exponential Build-up at MeV energies, Lorentz trapping at GeV energies); III. Pellet Fuel Fusion Prospects (Advanced Pellet Fuel Fusion Prospects, Burn Characteristics and Applications, Excitation-heating Prospects for Runaway Ion Temperatures). Inasmuch as the outline is very skeletal, a significant research and development effort may be in order to evaluate these prospects in more detail and hopefully ''harness the H-bomb'' for peaceful applications, the author concludes. 28 references

Confinement inertial fusion. Power reactors of nuclear fusion by lasers

International Nuclear Information System (INIS)

Velarde, G.; Ahnert, C.; Aragones, J.M.; Leira, G; Martinez-Val, J.M.

1980-01-01

The energy crisis and the need of the nuclear fusion energy are analized. The nuclear processes in the laser interation with the ablator material are studied, as well as the thermohydrodinamic processes in the implossion, and the neutronics of the fusion. The fusion reactor components are described and the economic and social impact of its introduction in the future energetic strategies.(author)

Industry's role in inertial fusion

International Nuclear Information System (INIS)

Glass, A.J.

1983-01-01

This paper is an address to the Tenth Symposium on Fusion Engineering. The speaker first addressed the subject of industry's role in inertial fusion three years earlier in 1980, outlining programs that included participation in the Shiva construction project, and the industrial participants' program set up in the laser fusion program to bring industrial scientists and engineers into the laboratory to work on laser fusion. The speaker is now the president of KMS Fusion, Inc., the primary industrial participant in the inertial fusion program. The outlook for fusion energy and the attitude of the federal government toward the fusion program is discussed

Enthalpies of fusion and enthalpies of solvation of aromatic hydrocarbons derivatives: Estimation of sublimation enthalpies at 298.15 K

Energy Technology Data Exchange (ETDEWEB)

Solomonov, Boris N., E-mail: boris.solomonov@kpfu.ru; Nagrimanov, Ruslan N.; Varfolomeev, Mikhail A.; Buzyurov, Aleksey V.; Mukhametzyanov, Timur A.

2016-03-20

Graphical abstract: - Highlights: • Solution enthalpies of aromatic hydrocarbons derivatives (ArHD) were measured at 298.15 K. • Solution enthalpies of ArHD in benzene at 298.15 K are equal to their fusion enthalpy at melting point. • Sublimation enthalpies of 80 ArHD were calculated as a sum of fusion and solvation enthalpies. • Obtained sublimation enthalpies are in good agreement with the recommended literature data. - Abstract: Enthalpy of sublimation of solid compound can be found using the values of solution enthalpy and solvation enthalpy in any solvent. In this work enthalpies of solution at infinite dilution of a number of aromatic hydrocarbons derivatives in benzene were measured at 298.15 K. Comparison between experimental and literature solution enthalpies in benzene at 298.15 K and fusion enthalpies at melting temperature of aromatic hydrocarbon derivatives showed, that these values are approximately equal. Thereby, fusion enthalpies at melting temperature can be used instead of their solution enthalpies in benzene at 298.15 K for calculation of sublimation enthalpies at 298.15 K. Solvation enthalpies in benzene at 298.15 K required for this procedure were calculated using group additivity scheme. The sublimation enthalpies of 80 aromatic hydrocarbons derivatives at 298.15 K were evaluated as a difference between fusion enthalpies at melting temperature and solvation enthalpies in benzene at 298.15 K. Obtained in this work values of sublimation enthalpy at 298.15 K for studied compounds were in a good agreement with available literature data.

Review of fusion synfuels

International Nuclear Information System (INIS)

Fillo, J.A.

1980-01-01

Thermonuclear fusion offers an inexhaustible source of energy for the production of hydrogen from water. Depending on design, electric generation efficiencies of approx. 40 to 60% and hydrogen production efficiencies by high-temperature electrolysis of approx. 50 to 65% are projected for fusion reactors using high-temperatures blankets. Fusion/coal symbiotic systems appear economically promising for the first generation of commercial fusion synfuels plants. Coal production requirements and the environmental effects of large-scale coal usage would be greatly reduced by a fusion/coal system. In the long term, there could be a gradual transition to an inexhaustible energy system based solely on fusion

Fusion technology programme

International Nuclear Information System (INIS)

Finken, D.

1984-10-01

The KfK-Association has continued work on 17 R and D contracts of the Fusion Technology Programme. An effort of 94 manyears per year is at present contributed by 10 KfK departments, covering all aereas defined in the Fusion Technology Programme. The dominant part of the work is directed towards the need of the NET design or supporting experiments. Some additional effort addresses long term technological issues and system studies relevant to DEMO or confinement schemes alternative to tokamaks. Direct contribution to the NET team has increased by augmentation of NET study contracts and delegation of personnel, three KfK delegates being at present members of the NET team. In reverse, specifications and design guidelines worked out by NET have started to have an impact on the current R and D-work in the laboratory. (orig./GG)

Fusion Canada issue 28

International Nuclear Information System (INIS)

1995-06-01

A short bulletin from the National Fusion Program highlighting in this issue the Canada - US fusion meeting in Montreal, fusion breeder work in Chile, new management at CFFTP, fast electrons in tokamaks: new data from TdeV, a program review of CCFM and Velikhov to address Montreal fusion meeting. 1 fig

The Contribution of Fusion to Sustainable Development

International Nuclear Information System (INIS)

Ward, D.

2006-01-01

The world demand for energy is projected to more than double over the next 50 years, indeed this will be essential to bring much of the world out of poverty. At the same time there is increasing pressure to substantially reduce atmospheric pollution, most notably of carbon dioxide. Together, these conflicting goals drive a need to produce enormous amounts of non-carbon energy supply, much greater than our total present energy supply. This presents an enormous challenge. As one of very few options for large-scale, non-carbon future supply of energy, fusion has the potential to make an important contribution to sustained energy supplies. Fusion's advantages of large fuel reserves, low atmospheric emissions and high levels of safety make it an important consideration in future energy strategies. - Fuel supplies are sufficient for at least thousands of years, and probably up to millions of years, of energy use. - Atmospheric emissions of CO 2 are very low and minor emissions of other pollutants are less harmful than those from most existing energy sources. - Hazards to the public will be very low because of the high levels of passive safety. - Waste materials will require little, or no, use of repository storage. Conceptual designs of fusion power plants have been optimised against safety and environmental criteria. The optimum designs vary both with the assessed progress in the development programme and according to the weight given to different criteria. The impact of this weighting on design, and the comparison of the outcomes with other energy sources, is described. To make a contribution to sustainable development, fusion must also be economically viable to enter the energy market. The calculated cost of electricity from fusion and other technologies, both new and existing, show that, particularly in an energy market where environmental constraints are playing an increasing role, fusion can make an important contribution. (author)

Economics of fusion research

Energy Technology Data Exchange (ETDEWEB)

None, None

1977-10-15

This report provides the results of a study of methods of economic analysis applied to the evaluation of fusion research. The study recognizes that a hierarchy of economic analyses of research programs exists: standard benefit-cost analysis, expected value of R and D information, and expected utility analysis. It is shown that standard benefit-cost analysis, as commonly applied to research programs, is inadequate for the evaluation of a high technology research effort such as fusion research. A methodology for performing an expected value analysis is developed and demonstrated and an overview of an approach to perform an expected utility analysis of fusion research is presented. In addition, a potential benefit of fusion research, not previously identified, is discussed and rough estimates of its magnitude are presented. This benefit deals with the effect of a fusion research program on optimal fossil fuel consumption patterns. The results of this study indicate that it is both appropriate and possible to perform an expected value analysis of fusion research in order to assess the economics of a fusion research program. The results indicate further that the major area of benefits of fusion research is likely due to the impact of a fusion research program on optimal fossil fuel consumption patterns and it is recommended that this benefit be included in future assessments of fusion research economics.

Economics of fusion research

International Nuclear Information System (INIS)

1977-01-01

This report provides the results of a study of methods of economic analysis applied to the evaluation of fusion research. The study recognizes that a hierarchy of economic analyses of research programs exists: standard benefit-cost analysis, expected value of R and D information, and expected utility analysis. It is shown that standard benefit-cost analysis, as commonly applied to research programs, is inadequate for the evaluation of a high technology research effort such as fusion research. A methodology for performing an expected value analysis is developed and demonstrated and an overview of an approach to perform an expected utility analysis of fusion research is presented. In addition, a potential benefit of fusion research, not previously identified, is discussed and rough estimates of its magnitude are presented. This benefit deals with the effect of a fusion research program on optimal fossil fuel consumption patterns. The results of this study indicate that it is both appropriate and possible to perform an expected value analysis of fusion research in order to assess the economics of a fusion research program. The results indicate further that the major area of benefits of fusion research is likely due to the impact of a fusion research program on optimal fossil fuel consumption patterns and it is recommended that this benefit be included in future assessments of fusion research economics

Nuclear fusion rate of the muonic T3 molecule

International Nuclear Information System (INIS)

Faghihi, F.; Eskandari, M. R.

2004-01-01

The ground state binding energy, size and effective nuclear charge of the muonic T 3 molecule are calculated using Born-Oppenheimer adiabatic approximation. The system possesses two minimum positions, one at typically muonic and the second at the atomic distances. A symmetric planar vibrational model between two minima is assumed and the approximated potential are calculated. Moreover, nuclear fusion rate calculations of the short-life molecule is carried out due to the overlap integral of the resonance nuclear compound nucleus and the molecular wave functions

Inertial fusion energy

International Nuclear Information System (INIS)

Decroisette, M.; Andre, M.; Bayer, C.; Juraszek, D.; Le Garrec, B.; Deutsch, C.; Migus, A.

2005-01-01

We first recall the scientific basis of inertial fusion and then describe a generic fusion reactor with the different components: the driver, the fusion chamber, the material treatment unit, the target factory and the turbines. We analyse the options proposed at the present time for the driver and for target irradiation scheme giving the state of art for each approach. We conclude by the presentation of LMJ (laser Megajoule) and NIF (national ignition facility) projects. These facilities aim to demonstrate the feasibility of laboratory DT ignition, first step toward Inertial Fusion Energy. (authors)

Low-Z coating as a first wall of nuclear fusion devices

International Nuclear Information System (INIS)

Shikama, Tatsuo; Okada, Masatoshi

1984-01-01

The tokamak nuclear fusion devices of the largest scale in the world, TFTR in USA and JET in Europe, started the operation from the end of 1982 to 1983. Also in Japan, the tokamak JT-60 is scheduled to begin the operation in 1985. One of the technological obstacles is the problem of first walls facing directly to plasma and subjected to high particle loading and thermal loading. Moreover, first walls achieve the active role of controlling impurities in plasma and recycling hydrogen isotopes. It is impossible to find a single material which satisfies all these requirements. The compounding of materials can create a material having new function, but also has the meaning of expanding the range of material selection. One of the material compounding methods is surface coating. In this paper, as the materials for first walls, the characteristics of low Z materials are discussed from the design examples of actual takamak nuclear fusion devices. The outline of first walls is explained. High priority is given to the impurity control in plasma, and in view of plasma energy emissivity and the rate of self sputtering, low Z material coating seems to be the solution. The merits and the problems of such low Z material coating are discussed. (Kako, I.)

Construction of hybrid peptide synthetases by module and domain fusions.

Science.gov (United States)

Mootz, H D; Schwarzer, D; Marahiel, M A

2000-05-23

Nonribosomal peptide synthetases are modular enzymes that assemble peptides of diverse structures and important biological activities. Their modular organization provides a great potential for the rational design of novel compounds by recombination of the biosynthetic genes. Here we describe the extension of a dimodular system to trimodular ones based on whole-module fusion. The recombinant hybrid enzymes were purified to monitor product assembly in vitro. We started from the first two modules of tyrocidine synthetase, which catalyze the formation of the dipeptide dPhe-Pro, to construct such hybrid systems. Fusion of the second, proline-specific module with the ninth and tenth modules of the tyrocidine synthetases, specific for ornithine and leucine, respectively, resulted in dimodular hybrid enzymes exhibiting the combined substrate specificities. The thioesterase domain was fused to the terminal module. Upon incubation of these dimodular enzymes with the first tyrocidine module, TycA, incorporating dPhe, the predicted tripeptides dPhe-Pro-Orn and dPhe-Pro-Leu were obtained at rates of 0.15 min(-1) and 2.1 min(-1). The internal thioesterase domain was necessary and sufficient to release the products from the hybrid enzymes and thereby facilitate a catalytic turnover. Our approach of whole-module fusion is based on an improved definition of the fusion sites and overcomes the recently discovered editing function of the intrinsic condensation domains. The stepwise construction of hybrid peptide synthetases from catalytic subunits reinforces the inherent potential for the synthesis of novel, designed peptides.

Fusion in the energy system

DEFF Research Database (Denmark)

Fusion energy is the fundamental energy source of the Universe, as the energy of the Sun and the stars are produced by fusion of e.g. hydrogen to helium. Fusion energy research is a strongly international endeavor aiming at realizing fusion energy production in power plants on Earth. Reaching...... of integration into the future electricity system and socio-economic studies of fusion energy will be presented, referring to the programme of Socio-Economic Research on Fusion (SERF) under the European Fusion Energy Agreement (EFDA)....

Membrane fusion and exocytosis.

Science.gov (United States)

Jahn, R; Südhof, T C

1999-01-01

Membrane fusion involves the merger of two phospholipid bilayers in an aqueous environment. In artificial lipid bilayers, fusion proceeds by means of defined transition states, including hourglass-shaped intermediates in which the proximal leaflets of the fusing membranes are merged whereas the distal leaflets are separate (fusion stalk), followed by the reversible opening of small aqueous fusion pores. Fusion of biological membranes requires the action of specific fusion proteins. Best understood are the viral fusion proteins that are responsible for merging the viral with the host cell membrane during infection. These proteins undergo spontaneous and dramatic conformational changes upon activation. In the case of the paradigmatic fusion proteins of the influenza virus and of the human immunodeficiency virus, an amphiphilic fusion peptide is inserted into the target membrane. The protein then reorients itself, thus forcing the fusing membranes together and inducing lipid mixing. Fusion of intracellular membranes in eukaryotic cells involves several protein families including SNAREs, Rab proteins, and Sec1/Munc-18 related proteins (SM-proteins). SNAREs form a novel superfamily of small and mostly membrane-anchored proteins that share a common motif of about 60 amino acids (SNARE motif). SNAREs reversibly assemble into tightly packed helical bundles, the core complexes. Assembly is thought to pull the fusing membranes closely together, thus inducing fusion. SM-proteins comprise a family of soluble proteins that bind to certain types of SNAREs and prevent the formation of core complexes. Rab proteins are GTPases that undergo highly regulated GTP-GDP cycles. In their GTP form, they interact with specific proteins, the effector proteins. Recent evidence suggests that Rab proteins function in the initial membrane contact connecting the fusing membranes but are not involved in the fusion reaction itself.

Compact fusion reactors

CERN Multimedia

CERN. Geneva

2015-01-01

Fusion research is currently to a large extent focused on tokamak (ITER) and inertial confinement (NIF) research. In addition to these large international or national efforts there are private companies performing fusion research using much smaller devices than ITER or NIF. The attempt to achieve fusion energy production through relatively small and compact devices compared to tokamaks decreases the costs and building time of the reactors and this has allowed some private companies to enter the field, like EMC2, General Fusion, Helion Energy, Lawrenceville Plasma Physics and Lockheed Martin. Some of these companies are trying to demonstrate net energy production within the next few years. If they are successful their next step is to attempt to commercialize their technology. In this presentation an overview of compact fusion reactor concepts is given.

EBFA: pulsed power for fusion

International Nuclear Information System (INIS)

Martin, T.H.; VanDevender, J.P.; Barr, G.W.; Johnson, D.L.

1979-01-01

This paper will describe the EBFA I accelerator under construction for inertial confinement fusion studies with particle beams and will update previous publications concerning particle beam fusion accelerators. Previous information included Proto I, a triggered oil insulated 1 TW accelerator; Proto II, a water insulated 10 TW accelerator; and EBFA I, a 30 TW, 1 MJ accelerator. Some modifications to the original design have occurred. A new pulse-forming-line concept has been developed which increases the flexibility of the accelerator. The major problem of vacuum interface flashover has been solved by the use of long, magnetically-insulated, transmission lines. The first production module of EBFA I has been received, assembled, and is now undergoing extensive testing. The technology is extendable to at least a factor of ten above the projected EBFA capabilities of 30 TW and 1 MJ output. Progress on facilities associated with the Sandia Particle Beam fusion program is reported

Fusion research activities in China

International Nuclear Information System (INIS)

Deng Xiwen

1998-01-01

The fusion program in China has been executed in most areas of magnetic confinement fusion for more than 30 years. Basing on the situation of the power supply requirements of China, the fusion program is becoming an important and vital component of the nuclear power program in China. This paper reviews the status of fusion research and next step plans in China. The motivation and goal of the Chinese fusion program is explained. Research and development on tokamak physics and engineering in the southwestern institute of physics (SWIP) and the institute of plasma physics of Academic Sinica (ASIPP) are introduced. A fusion breeder program and a pure fusion reactor design program have been supported by the state science and technology commission (SSTC) and the China national nuclear corporation (CNNC), respectively. Some features and progress of fusion reactor R and D activities are reviewed. Non fusion applications of plasma science are an important part of China fusion research; a brief introduction about this area is given. Finally, an introductional collaboration network on fusion research activities in China is reported. (orig.)

Inertial fusion science in Europe

International Nuclear Information System (INIS)

Bigot, B.

2006-01-01

Europe has built significant laser facilities to study inertial confinement fusion since the beginning of this science. The goal is to understand the processes of ignition and propagation of thermonuclear combustion. Three routes toward fusion are pursued, each of which has advantages and difficulties. The conventional routes are using a central hot spot created by the same compression and heating laser beams, either with indirect or direct drive. A more recent route, 'fast ignition', has been actively studied since the 90's, increasing the need for very high energy lasers to create the hot spot; some European lasers of this kind are already functioning, others are under construction or planned. Among European facilities, Laser Mega Joule (LMJ), which is under construction, will be the most powerful tool at the end of the decade, along with NIF in the Usa, to study and obtain fusion. LMJ is designed not only to obtain fusion but also to carry out experiments on all laser-plasma physics themes thanks to its flexibility. This facility, mainly dedicated to defence programmes, will be accessible to the academic research community. On all these facilities, numerous results are and will be obtained in the fields of High Energy Density Physics and Ultra High Intensity. (author)

Fusion for Energy: The European joint undertaking for ITER and the development of fusion energy

International Nuclear Information System (INIS)

Diegele, E.

2009-01-01

environment and conditions. Materials and materials technologies (fabrication, welding, joining) have to be fully qualified in front of a rigorous licensing process within the next decade. Therefore, materials development for DEMO is based on present technologies and knowledge with some reasonable extrapolation. The 9% Cr steel EUROFER steel is the primary EU candidate structural material. For increased thermal efficiency the temperature window of the structural materials needs to be enlarged. Various ODS (Oxide Dispersion Strengthened) Fe-Cr-steels are candidates for higher temperature application. The large fraction of high energy neutrons in the fusion neutron spectrum results in gaseous transmutations (He and H) that are more than one order of magnitude higher than in fission. Even though fission based material test reactors are the essential and indispensable pillar of the current and future irradiation qualification programme, they can not provide sufficient data for a successful licensing process towards DEMO. For this reason, the construction and use of a facility called IFMIF, designed for simulating as closely a possible the fusion neutron spectrum, is mandatory. Meantime, and complimentary, an enhanced material science programme should increase knowledge and understanding of radiation effects. The focus of this programme for the next decade should be on the development and validation of predictive capabilities for modelling micro-structural evolution and mechanical properties of EUROFER-type steels under fusion reactor relevant conditions, addressing in particular the Helium issue. In a longer term perspective, this should result in the implementation of an integrated approach involving modelling and model-oriented experimental validation into a strategy of accelerated development and testing of candidate fusion materials, material systems and material technologies. (author)

Elicitor Mixtures Significantly Increase Bioactive Compounds, Antioxidant Activity, and Quality Parameters in Sweet Bell Pepper

Directory of Open Access Journals (Sweden)

Lina Garcia-Mier

2015-01-01

Full Text Available Sweet bell peppers are greatly appreciated for their taste, color, pungency, and aroma. Additionally, they are good sources of bioactive compounds with antioxidant activity, which can be improved by the use of elicitors. Elicitors act as metabolite-inducing factors (MIF by mimic stress conditions. Since plants rarely experience a single stress condition one by one but are more likely to be exposed to simultaneous stresses, it is important to evaluate the effect of elicitors on plant secondary metabolism as mixtures. Jasmonic acid (JA, hydrogen peroxide (HP, and chitosan (CH were applied to fruits and plants of bell pepper as mixtures. Bioactive compounds, antioxidant activity, and quality parameters were evaluated. The assessed elicitor cocktail leads to an increase in the variables evaluated (P ≤ 0.05 when applied to mature fruits after harvest, whereas the lowest values were observed in the treatment applied to immature fruits. Therefore, the application of the elicitor cocktail to harvested mature fruits is recommended in order to improve bioactive compounds and the antioxidant activity of sweet bell peppers.

Applications of Skyrme energy-density functional to fusion reactions spanning the fusion barriers

International Nuclear Information System (INIS)

Liu Min; Wang, Ning; Li Zhuxia; Wu Xizhen; Zhao Enguang

2006-01-01

The Skyrme energy density functional has been applied to the study of heavy-ion fusion reactions. The barriers for fusion reactions are calculated by the Skyrme energy density functional with proton and neutron density distributions determined by using restricted density variational (RDV) method within the same energy density functional together with semi-classical approach known as the extended semi-classical Thomas-Fermi method. Based on the fusion barrier obtained, we propose a parametrization of the empirical barrier distribution to take into account the multi-dimensional character of real barrier and then apply it to calculate the fusion excitation functions in terms of barrier penetration concept. A large number of measured fusion excitation functions spanning the fusion barriers can be reproduced well. The competition between suppression and enhancement effects on sub-barrier fusion caused by neutron-shell-closure and excess neutron effects is studied

Radiation damage calculations for compound materials

International Nuclear Information System (INIS)

Greenwood, L.R.

1989-01-01

Displacement damage calculations can be performed for 40 elements in the energy range up to 20 MeV with the SPECTER computer code. A recent addition to the code, called SPECOMP, can intermix atomic recoil energy distributions for any four elements to calculate the proper displacement damage for compound materials. The calculations take advantage of the atomic recoil data in the SPECTER libraries, which were determined by the DISCS computer code, using evaluated neutron cross section and angular distribution data in ENDF/B-V. Resultant damage cross sections for any compound can be added to the SPECTER libraries for the routine calculation of displacements in any given neutron field. Users do not require access to neutron cross section files. Results are presented for a variety of fusion materials and a new ceramic superconductor material. Future plans and nuclear data needs are discussed. 11 refs., 6 figs., 1 tab

Multimerized CHR-derived peptides as HIV-1 fusion inhibitors.

Science.gov (United States)

Nomura, Wataru; Hashimoto, Chie; Suzuki, Takaharu; Ohashi, Nami; Fujino, Masayuki; Murakami, Tsutomu; Yamamoto, Naoki; Tamamura, Hirokazu

2013-08-01

To date, several HIV-1 fusion inhibitors based on the carboxy-terminal leucine/isoleucine heptad repeat (CHR) region of an HIV-1 envelope protein gp41 have been discovered. We have shown that a synthetic peptide mimetic of a trimer form of the CHR-derived peptide C34 has potent inhibitory activity against the HIV-1 fusion mechanism, compared to a monomer C34 peptide. The present study revealed that a dimeric form of C34 is evidently structurally critical for fusion inhibitors, and that the activity of multimerized CHR-derived peptides in fusion inhibition is affected by the properties of the unit peptides C34, SC34EK, and T20. The fluorescence-based study suggested that the N36-interactive sites of the C34 trimer, including hydrophobic residues, are exposed outside the trimer and that trimerization of C34 caused a remarkable increase in fusion inhibitory activity. The present results could be useful in the design of fusion inhibitors against viral infections which proceed via membrane fusion with host cells. Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

Cold fusion research

International Nuclear Information System (INIS)

1989-11-01

I am pleased to forward to you the Final Report of the Cold Fusion Panel. This report reviews the current status of cold fusion and includes major chapters on Calorimetry and Excess Heat, Fusion Products and Materials Characterization. In addition, the report makes a number of conclusions and recommendations, as requested by the Secretary of Energy

Towards fusion power

International Nuclear Information System (INIS)

Venkataraman, G.

1975-01-01

An attempt has been made to present general but broad review of the recent developments in the field of plasma physics and its application to fusion power. The first chapter describes the fusion reactions and fusion power systems. The second chapter deals in detail with production and behaviour of plasma, screening, oscillations, instability, energy losses, temperature effects, etc. Magnetic confinements, including pinch systems, toroidal systems such as Tokamac and stellarator, minor machine, etc. are discussed in detail in chapter III. Laser produced plasma, laser implosion and problems associated with it and future prospects are explained in chapter IV. Chapter V is devoted entirely to the various aspects of hybrid systems. The last chapter throws light on problems of fusion technology, such as plasma heating, vacuum requirements, radiation damage, choice of materials, blanket problems, hazards of fusion reactions, etc. (K.B.)

Pulsed fission/fusion hybrid engines

International Nuclear Information System (INIS)

Hudson, G.C.

1979-01-01

Research into high-thrust, high-specific impulse rocket engines using energy from nuclear reactions which has been conducted at this organization will be discussed. The engines are all conceptual in nature, yet are within the realization of conventional or near-term technology. The engine concepts under study at Foundation, Inc. are designed to obviate or minimize these negative effects of the ORION scheme. By using non-chemical triggers to initiate a non-breakeven fusion reaction at the core of a target composed of both fission and fusion fuel, it should be possible to employ the fusion neutrons thus produced to begin a fission reaction in U-235 or Pu-239. Since the density of the target can be increased by as much as a factor of 250 through compression of the pellet, the amount of fission material necessary to produce a critical mass can be greatly reduced. (This also means that the amount of fission products produced for a giventhrust level is also reduced from the ORION levels.) Coupling this eeffect to the large number of 14 MeV fusion neutrons produced early in the compression process and subsequently to the heating of some additional fusion fuel surrounding the critical mass leads to the very efficient burnup of the target. This insures both high yield from the target as well as low cost per MJ energy released. Finally, the use of such small pellets allows the scale of the energy released to be tailored to a level usable in rocket engines of a few tens of tons thrust level. (orig.) [de

Heavy ion fusion

International Nuclear Information System (INIS)

Bangerter, R.O.

1986-01-01

This report on the International Symposium on Heavy Ion Fusion held May 27-29, 1986 summarizes the problems and achievements in the areas of targets, accelerators, focussing, reactor studies, and system studies. The symposium participants recognize that there are large uncertainties in Heavy Ion Fusion but many of them are also optimistic that HIF may ultimately be the best approach to fusion

The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein

Directory of Open Access Journals (Sweden)

Semaan Sheila J

2010-10-01

Full Text Available Abstract Background Many chemotherapeutic agents promote tumor cell death by activating the intrinsic pathway of apoptosis. Intrinsic apoptosis involves permeabilization of the mitochondrial outer membrane and the release of cytochrome c, a process that is controlled by proteins of the BCL2 gene family. Chemoresistance is often associated with abnormalities in concentrations of BCL2 family proteins. Although stoichiometirc interactions between anti-apoptotic and BH3-only BCL2 family proteins have been well documented as affecting cell death, the association between changes in BAX concentration and intrinsic apoptosis are poorly understood. Methods Exogenous GFP-murine Bax fusion constructs were transfected into BAX-deficient HCT116 cells. To titrate the expression of the fusion protein, GFP-BAX was cloned into a tetracycline sensitive expression cassette and cotransfected with a plasmid expressing the rtTA transcription factor into HCT116BAX-/- cells. Linear expression of the fusion gene was induced with doxycycline and monitored by quantitative PCR and immunoblotting. Cell death was assayed by DAPI staining cells after exposure to indomethacin, and scoring nuclei for condensed chromatin and fragmented nuclei. Results HCT116BAX-/- cells were resistant to indomethacin, but susceptibility could be recovered in cells expressing a GFP-BAX fusion protein. Titration of GFP-BAX expression revealed that the concentration of BAX required to induce a saturating apoptosis response from baseline, was rapidly achieved. Increased levels of GFP-BAX were unable to stimulate higher levels of cell death. Examination of GFP-BAX distribution before and after indomethacin treatment indicated that BAX protein did not form aggregates when present at sub-lethal concentrations. Conclusion Within the limitations of this experimental system, BAX-dependent apoptosis in HCT116 cells exhibits an all-or-none response depending on the level of BAX protein present. The lack of

Can gene fusions serve for fingerprints of radiogenic cancers?

International Nuclear Information System (INIS)

Nakamura, Nori

2016-01-01

It has been recognized that malignancies in blood cells often bear specific chromosome translocations or gene fusions. In recent years, the presence of fusion genes became to be known also among solid cancers as driver mutations. However, representative solid cancers bearing specific gene fusions are limited to cancers of thyroid, prostate, and sarcomas among which only thyroid cancer risk is known to be related to radiation exposures. On the other hand, it is extremely rare to find recurrent reciprocal translocations among common cancers such as in the lung, stomach, breast, and colon, which form a major component of radiation risks. It is therefore unlikely that radiation increases the risk of cancer by inducing specific translocations (gene fusions) but more likely through induction of mutations (including deletions). Although gene fusions could play a role in radiation carcinogenesis, it does not seem good enough to serve for a radiation fingerprint. (author)

Fusion and technology: An introduction to the physics and technology of magnetic confinment fusion

International Nuclear Information System (INIS)

Stacey, W.M.

1984-01-01

This book is an introduction covering all aspects of magnetic fusion and magnetic fusion technology. Physical property data relevant to fusion technology and a summary of fusion reactor design parameters are provided. Topics covered include: basic properties; equilibrium and transport confinement concepts; plasma heating; plasma wall interaction; magnetics; energy storage and transfer; interaction of radiation with matter; primary energy conversion and tritium breeding blanket; tritium and vacuum; and Fusion Reactor Design

Synthesis, growth, and studies (crystal chemistry, magnetic chemistry) of actinide-based intermetallic compounds and alloys with a 1.1.1 stoichiometry

International Nuclear Information System (INIS)

Kergadallan, Yann

1993-01-01

The first part of this research thesis reports the study of the synthesis and reactivity of intermetallic compounds with a 1.1.1 stoichiometry. It presents the thermal properties of 1.1.1 compounds: general presentation of physical transitions, and of solid solutions and formation heat, application to actinides (reactivity analysis from phase diagrams, techniques of crystal synthesis and crystal growth. It describes experimental techniques: synthesis, determination of fusion temperature by dilatometry, methods used for crystal growth, characterisation techniques (metallography, X ray diffraction on powders, dilatometry). It discusses the obtained results in terms of characterisation of synthesised samples, of crystal growth, and of measurements of fusion temperature. The second part addresses crystal chemistry studies: structure of compounds with a 1.1.1 stoichiometry (Laves structures, Zr, Ti and Pu compounds), techniques of analysis by X-ray diffraction (on powders and on single crystals), result interpretation (UNiX compounds, AnTAl compounds with T being a metal from group VIII, AnTGa compounds, AnNiGe compounds, distance comparison, structure modifications under pressure). The third part concerns physical issues. The author addresses the following topics: physical properties of intermetallic 1.1.1 compounds (magnetism of yttrium phases, behaviour of uranium-based Laves phases, analysis of pseudo-binary diagrams, physical characteristics of uranium-based 1.1.1 compounds, predictions of physical measurements), analysis techniques (Moessbauer spectroscopy, SQUID for Superconducting Quantum Interference Device), and result interpretation

Use of high current density superconducting coils in fusion devices

International Nuclear Information System (INIS)

Green, M.A.

1979-11-01

Superconducting magnets will play an important role in fusion research in years to come. The magnets which are currently proposed for fusion research use the concept of cryostability to insure stable operation of the superconducting coils. This paper proposes the use of adiabatically stable high current density superconducting coils in some types of fusion devices. The advantages of this approach are much lower system cold mass, enhanced cryogenic safety, increased access to the plasma and lower cost

Cold fusion

International Nuclear Information System (INIS)

Koster, J.

1989-01-01

In this contribution the author the phenomenom of so-called cold fusion, inspired by the memorable lecture of Moshe Gai on his own search for this effect. Thus much of what follows was presented by Dr. Gai; the rest is from independent reading. What is referred to as cold fusion is of course the observation of possible products of deuteron-deuteron (d-d) fusion within deuterium-loaded (dentended) electrodes. The debate over the two vanguard cold fusion experiments has raged under far more public attention than usually accorded new scientific phenomena. The clamor commenced with the press conference of M. Fleishmann and S. Pons on March 23, 1989 and the nearly simultaneous wide circulation of a preprint of S. Jones and collaborators. The majority of work attempting to confirm these observations has at the time of this writing yet to appear in published form, but contributions to conferences and electronic mail over computer networks were certainly filled with preliminary results. To keep what follows to a reasonable length the author limit this discussion to the searches for neutron (suggested by ref. 2) or for excessive heat production (suggested by ref. 1), following a synopsis of the hypotheses of cold fusion

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

Directory of Open Access Journals (Sweden)

Qingsong Gao

2018-04-01

Full Text Available Summary: Gene fusions represent an important class of somatic alterations in cancer. We systematically investigated fusions in 9,624 tumors across 33 cancer types using multiple fusion calling tools. We identified a total of 25,664 fusions, with a 63% validation rate. Integration of gene expression, copy number, and fusion annotation data revealed that fusions involving oncogenes tend to exhibit increased expression, whereas fusions involving tumor suppressors have the opposite effect. For fusions involving kinases, we found 1,275 with an intact kinase domain, the proportion of which varied significantly across cancer types. Our study suggests that fusions drive the development of 16.5% of cancer cases and function as the sole driver in more than 1% of them. Finally, we identified druggable fusions involving genes such as TMPRSS2, RET, FGFR3, ALK, and ESR1 in 6.0% of cases, and we predicted immunogenic peptides, suggesting that fusions may provide leads for targeted drug and immune therapy. : Gao et al. analyze a 9,624 sample TCGA cohort with 33 cancer types to detect gene fusion events. They provide a landscape of fusion events detected, relate fusions to gene expression, focus on kinase fusion structures, examine mutually exclusive mutation and fusion patterns, and highlight fusion druggability. Keywords: fusion, cancer, RNA, translocation, gene fusions

Fusion Canada issue 10

International Nuclear Information System (INIS)

1990-02-01

A short bulletin from the National Fusion Program. Included in this issue is a report on Fusion Materials Research, ITER physics research, fusion performance record at JET, and design options for reactor building. 4 figs

Inertial confinement fusion

International Nuclear Information System (INIS)

Nuckolls, J.H.; Wood, L.L.

1988-01-01

Edward Teller has been a strong proponent of harnessing nuclear explosions for peaceful purposes. There are two approaches: Plowshare, which utilizes macro- explosions, and inertial confinement fusion, which utilizes microexplosions. The development of practical fusion power plants is a principal goal of the inertial program. It is remarkable that Teller's original thermonuclear problem, how to make super high yield nuclear explosions, and the opposite problem, how to make ultra low yield nuclear explosions, may both be solved by Teller's radiation implosion scheme. This paper reports on the essential physics of these two thermonuclear domains, which are separated by nine orders of magnitude in yield, provided by Teller's similarity theorem and its exceptions. Higher density makes possible thermonuclear burn of smaller masses of fuel. The leverage is high: the scale of the explosion diminishes with the square of the increase in density. The extraordinary compressibility of matter, first noticed by Teller during the Los Alamos atomic bomb program, provides an almost incredible opportunity to harness fusion. The energy density of thermonuclear fuels isentropically compressed to super high-- -densities---even to ten thousand times solid density---is small compared to the energy density at thermonuclear ignition temperatures. In small masses of fuel imploded to these super high matter densities, the energy required to achieve ignition may be greatly reduced by exploiting thermonuclear propagation from a relatively small hot spot

Strategic plan for the restructured US fusion energy sciences program

International Nuclear Information System (INIS)

1996-08-01

This plan reflects a transition to a restructured fusion program, with a change in focus from an energy technology development program to a fusion energy sciences program. Since the energy crisis of the early 1970's, the U.S. fusion program has presented itself as a goal- oriented fusion energy development program, with milestones that required rapidly increasing budgets. The Energy Policy Act of 1992 also called for a goal-oriented development program consistent with the Department's planning. Actual funding levels, however, have forced a premature narrowing of the program to the tokamak approach. By 1995, with no clear, immediate need driving the schedule for developing fusion energy and with enormous pressure to reduce discretionary spending, Congress cut fusion program funding for FY 1996 by one-third and called for a major restructuring of the program. Based on the recommendations of the Fusion Energy Advisory Committee (FEAC), the Department has decided to pursue a program that concentrates on world-class plasma, science, and on maintaining an involvement in fusion energy science through international collaboration. At the same time, the Japanese and Europeans, with energy situations different from ours, are continuing with their goal- oriented fusion programs. Collaboration with them provides a highly leveraged means of continued involvement in fusion energy science and technology, especially through participation in the engineering and design activities of the International Thermonuclear Experimental Reactor program, ITER. This restructured fusion energy sciences program, with its focus on fundamental fusion science and technology, may well provide insights that lead to more attractive fusion power plants, and will make use of the scientific infrastructure that will allow the United States to launch a fusion energy development program at some future date

The restructured fusion program and the role of alternative fusion concepts

International Nuclear Information System (INIS)

Perkins, L.J.

1996-01-01

This testimony to the subcommittee on Energy and the Environment of the U.S. House of Representatives's Committee on Science pushes for about 25% of the fusion budget to go to alternative fusion concepts. These concepts are: low density magnetic confinement, inertial confinement fusion, high density magnetic confinement, and non- thermonuclear and miscellaneous programs. Various aspects of each of these concepts are outlined

Magnetic fusion technology

CERN Document Server

Dolan, Thomas J

2014-01-01

Magnetic Fusion Technology describes the technologies that are required for successful development of nuclear fusion power plants using strong magnetic fields. These technologies include: ? magnet systems, ? plasma heating systems, ? control systems, ? energy conversion systems, ? advanced materials development, ? vacuum systems, ? cryogenic systems, ? plasma diagnostics, ? safety systems, and ? power plant design studies. Magnetic Fusion Technology will be useful to students and to specialists working in energy research.

Mirror fusion--fission hybrids

International Nuclear Information System (INIS)

Lee, J.D.

1978-01-01

The fusion-fission concept and the mirror fusion-fission hybrid program are outlined. Magnetic mirror fusion drivers and blankets for hybrid reactors are discussed. Results of system analyses are presented and a reference design is described

The heavy ion fusion program in the USA

International Nuclear Information System (INIS)

Bangerter, R.O.; Davidson, R.C.; Herrmannsfeldt, W.B.; Lindl, J.; Meier, W.R.; Logan, B.G.

2001-01-01

Inertial fusion energy research has enjoyed increased interest and funding. This has allowed expanded programs in target design, target fabrication, fusion chamber research, target injection and tracking, and accelerator research. The target design effort examines ways to minimize the beam power and energy and increase the allowable focal spot size while preserving target gain. Chamber research for heavy ion fusion emphasizes the use of thick liquid walls to serve as the coolant, breed tritium, and protect the structural wall from neutrons, photons, and other target products. Several small facilities are now operating to model fluid chamber dynamics. A facility to study target injection and tracking has been built and a second facility is being designed. Improved economics is an important goal of the accelerator research. The accelerator research is also directed toward the design of an Integrated Research Experiment (IRE). The IRE is being designed to accelerate ions to >100 MeV, enabling experiments in beam dynamics, focusing, and target physics. Activities leading to the IRE include ion source development and a High Current Experiment (HCX) designed to transport and accelerate a single beam of ions with a beam current of approximately 1 A, the initial current required for each beam of a fusion driver. In terms of theory, the program is developing a source-to-target numerical simulation capability. The goal of the entire program is to enable an informed decision about the promise of heavy ion fusion in about a decade. (author)

A light water excess heat reaction suggests that cold fusion may be alkali-hydrogen fusion

International Nuclear Information System (INIS)

Bush, R.T.

1992-01-01

This paper reports that Mills and Kneizys presented data in support of a light water excess heat reaction obtained with an electrolytic cell highly reminiscent of the Fleischmann-Pons cold fusion cell. The claim of Mills and Kneizys that their excess heat reaction can be explained on the basis of a novel chemistry, which supposedly also explains cold fusion, is rejected in favor of their reaction being, instead, a light water cold fusion reaction. It is the first known light water cold fusion reaction to exhibit excess heat, it may serve as a prototype to expand our understanding of cold fusion. From this new reactions are deduced, including those common to past cold fusion studies. This broader pattern of nuclear reactions is typically seen to involve a fusion of the nuclides of the alkali atoms with the simplest of the alkali-type nuclides, namely, protons, deuterons, and tritons. Thus, the term alkali-hydrogen fusion seems appropriate for this new type of reaction with three subclasses: alkali-hydrogen fusion, alkali-deuterium fusion, and alkali-tritium fusion. A new three-dimensional transmission resonance model (TRM) is sketched. Finally, preliminary experimental evidence in support of the hypothesis of a light water nuclear reaction and alkali-hydrogen fusion is reported. Evidence is presented that appears to strongly implicate the transmission resonance phenomenon of the new TRM

A generative model for probabilistic label fusion of multimodal data

DEFF Research Database (Denmark)

Iglesias, Juan Eugenio; Sabuncu, Mert Rory; Van Leemput, Koen

2012-01-01

The maturity of registration methods, in combination with the increasing processing power of computers, has made multi-atlas segmentation methods practical. The problem of merging the deformed label maps from the atlases is known as label fusion. Even though label fusion has been well studied for...

Spatial resolution enhancement of satellite image data using fusion approach

Science.gov (United States)

Lestiana, H.; Sukristiyanti

2018-02-01

Object identification using remote sensing data has a problem when the spatial resolution is not in accordance with the object. The fusion approach is one of methods to solve the problem, to improve the object recognition and to increase the objects information by combining data from multiple sensors. The application of fusion image can be used to estimate the environmental component that is needed to monitor in multiple views, such as evapotranspiration estimation, 3D ground-based characterisation, smart city application, urban environments, terrestrial mapping, and water vegetation. Based on fusion application method, the visible object in land area has been easily recognized using the method. The variety of object information in land area has increased the variation of environmental component estimation. The difficulties in recognizing the invisible object like Submarine Groundwater Discharge (SGD), especially in tropical area, might be decreased by the fusion method. The less variation of the object in the sea surface temperature is a challenge to be solved.

The IGNITEX fusion project

International Nuclear Information System (INIS)

Carrera, R.

1987-01-01

The author discusses the recently proposed fusion ignition experiment, IGNITEX. He emphasizes the basic ideas of this concept rather than the specific details of the physics and engineering aspects of the experiment. This concept is a good example of the importance of maintaining an adequate balance between the basic scientific progress in fusion physics and the new technologies that are becoming available in order to make fusion work. The objective of the IGNITEX project is to produce and control ignited plasmas for scientific study in the simplest and least expensive way possible. Being able to study this not-yet-produced regime of plasma operation is essential to fusion research. Two years after the fission nuclear reaction was discovered, a non-self-sustained fission reaction was produced in a laboratory, and in one more year a self-sustained reaction was achieved at the University of Chicago. However, after almost forty years of fusion research, a self-sustained fusion reaction has yet not been produced in a laboratory experiment. This fact indicates the greater difficulty of the fusion experiment. Because of the difficulty involved in the production of a self-sustained fusion reaction, it is necessary to propose such an experiment with maximum ignition margins, maximum simplicity, and minimum financial risk

Fusion: Energy for the future

International Nuclear Information System (INIS)

1991-05-01

Fusion, which occurs in the sun and the stars, is a process of transforming matter into energy. If we can harness the fusion process on Earth, it opens the way to assuring that future generations will not want for heat and electric power. The purpose of this booklet is to introduce the concept of fusion energy as a viable, environmentally sustainable energy source for the twenty-first century. The booklet presents the basic principles of fusion, the global research and development effort in fusion, and Canada's programs for fusion research and development

Fusion, magnetic confinement

International Nuclear Information System (INIS)

Berk, H.L.

1992-01-01

An overview is presented of the principles of magnetic confinement of plasmas for the purpose of achieving controlled fusion conditions. Sec. 1 discusses the different nuclear fusion reactions which can be exploited in prospective fusion reactors and explains why special technologies need to be developed for the supply of tritium or 3 He, the probable fuels. In Sec. 2 the Lawson condition, a criterion that is a measure of the quality of confinement relative to achieving fusion conditions, is explained. In Sec. 3 fluid equations are used to describe plasma confinement. Specific confinement configurations are considered. In Sec. 4 the orbits of particle sin magneti and electric fields are discussed. In Sec. 5 stability considerations are discussed. It is noted that confinement systems usually need to satisfy stability constraints imposed by ideal magnetohydrodynamic (MHD) theory. The paper culminates with a summary of experimental progress in magnetic confinement. Present experiments in tokamaks have reached the point that the conditions necessary to achieve fusion are being satisfied

Dynamics of 28,30S i* compound nuclei formed at sub-barrier energies

Science.gov (United States)

Kaur, Manpreet; Singh, Bir Bikram; Kaur, Sarbjeet

2018-05-01

The decay of 28S i* and 30S i* compound nuclei (CN) formed at sub-barrier energies, in the reactions induced by stable projectile 16O and exotic projectile 18O, respectively, has been investigated within the quantum mechanical fragmentation theory based dynamical cluster-decay model (DCM). The collective potential energy surface shows that xα-type (x is an integer) clusters are minimized in the decay of 28S i* while in case of 30S i* in addition to xα-type clusters, np-xα (n, p are neutron and proton, respectively) type clusters are also minimized. These minimized fragments have more preformation probability P0, which is an important factor through which nuclear structure effects of decaying CN are probed, within DCM. The results show that light particles (LPs) are contributing mostly in the fusion cross-section, σfusion. In case of 30S i*, the contribution of 1n is highest and more compared to 4He in case of 28S i*, which seems to play an important role in fusion enhancement. The DCM calculated σfusion for both the CN formed with same Ec.m. = 7.0 MeV gives more value for σfusion of 30S i*, in agreement with the experimental data.

FUSION technology programme 2003-2006

International Nuclear Information System (INIS)

Karttunen, S.; Rantamaeki, K.

2007-01-01

This report summarises the results of the FUSION technology programme during the period between 2003-2006. FUSION is a continuation of the previous FFusion and FFusion2 technology programmes that took place from 1993 to 2002. The FUSION technology programme was fully integrated into the European Fusion Programme in the sixth Framework Programme (Euratom), through the bilateral Contract of Association between Euratom and Tekes and the multilateral European Fusion Development Agreement (EFDA). The Association Euratom-Tekes was established in 1995. At the moment, there are 26 Euratom Fusion associations working together as an European Research Area. There are four research areas in the FUSION technology programme: (1) fusion physics and plasma engineering, (2) vessel/in-vessel materials, joints and components, (3) in-vessel remote handling systems, and (4) system studies. The FUSION team consists of research groups from the Technical Research Centre of Finland (VTT), the Helsinki, Tampere and Lappeenranta Universities of Technology and the University of Helsinki. The co-ordinating unit is VTT. A key element of the FUSION programme is the close collaboration between VTT, the universities and the industry, which has resulted in dynamic and sufficiently large research teams to tackle challenging research and development projects. The distribution of work between research institutes and industry has also been clear. Industrial activities related to the FUSION programme are co-ordinated through the 'Big Science' Project by Finpro and Prizztech. The total expenditure of the FUSION technology programme for 2003-2006 amounted to euro 14,9 million in research work at VTT and the universities with an additional euro 3,5 million for projects by the Finnish companies including the industry co-ordination. The funding of the FUSION programme and related industrial projects was mainly provided by Tekes (37%), Euratom (38%) and the participating institutes and industry (24%). The

Perceptual Relearning of Binocular Fusion and Stereoacuity After Brain Injury.

Science.gov (United States)

Schaadt, Anna-Katharina; Schmidt, Lena; Reinhart, Stefan; Adams, Michaela; Garbacenkaite, Ruta; Leonhardt, Eva; Kuhn, Caroline; Kerkhoff, Georg

2014-06-01

Brain lesions may disturb binocular fusion and stereopsis, leading to blurred vision, diplopia, and reduced binocular depth perception for which no evaluated treatment is currently available. Objective The study evaluated the effects of a novel binocular vision treatment designed to improve convergent fusional amplitude and stereoacuity in patients with stroke or traumatic brain injury (TBI). Methods Patients (20 in all: 11 with stroke, 9 with TBI) were tested in fusional convergence, stereoacuity, near/far visual acuity, accommodation, and subjective binocular reading time until diplopia emerged at 6 different time points. All participants were treated in a single subject baseline design, with 3 baseline assessments before treatment (pretherapy), an assessment immediately after a 6-week treatment period (posttherapy), and 2 follow-up tests 3 and 6 months after treatment. Patients received a novel fusion and dichoptic training using 3 different devices to slowly increase fusional and disparity angles. Results At pretherapy, the stroke and TBI groups showed severe impairments in convergent fusional range, stereoacuity, subjective reading duration, and partially in accommodation (only TBI group). After treatment, both groups showed considerable improvements in all these variables as well as slightly increased near visual acuity. No significant changes were observed during the pretherapy and follow-up periods, ruling out spontaneous recovery and demonstrating long-term stability of binocular treatment effects. Conclusions This proof-of-principle study indicates a substantial treatment-induced plasticity of the lesioned brain in the relearning of binocular fusion and stereovision, thus providing new, effective rehabilitation strategies to treat binocular vision deficits resulting from permanent visual cortical damage. © The Author(s) 2013.

The elementary fusion modalities of osteoclasts

DEFF Research Database (Denmark)

Søe, Kent; Hobolt-Pedersen, Anne Sofie; Delaisse, Jean Marie

2015-01-01

, are not known for the osteoclast. Here we show that osteoclast fusion partners are characterized by differences in mobility, nuclearity, and differentiation level. Our demonstration was based on time-laps videos of human osteoclast preparations from three donors where 656 fusion events were analyzed. Fusions......The last step of the osteoclast differentiation process is cell fusion. Most efforts to understand the fusion mechanism have focused on the identification of molecules involved in the fusion process. Surprisingly, the basic fusion modalities, which are well known for fusion of other cell types...... between a mobile and an immobile partner were most frequent (62%), while fusion between two mobile (26%) or two immobile partners (12%) was less frequent (p fusion partner contained more nuclei than the mobile one (p

Inertial fusion with hypervelocity impact

International Nuclear Information System (INIS)

Olariu, S.

1998-01-01

resulting temperature being supposed sufficient to ignite the fusion reactions between the deuterium-tritium nuclei contained by the fuel target at rest. The fusion reactions thus ignited will be propagated in the entire volume of the large-yield target. In this analysis it was required that the energy produced by fusion reactions should be equal to the energy of the incident projectile. Assuming that the incident projectile is positively charged, the estimated length of the linac that would accelerate the projectile to the threshold velocity is 13 km, if deuterium-tritium densities of 570 g cm -3 could be obtained by compression. The required accelerating length is comparable to the lengths of linacs being considered in the field of high energy physics. At pressures of 10 -11 Torr in the accelerating column the heating and the ionization produced by the interaction of the incident projectile with the background gas molecules are found to be within acceptable limits. Unlike usual accelerators where a large number of particles are accelerated at a time, in the case of impact fusion the incident projectiles would be accelerated one at a time. This opens the possibility that an accelerating wave front should be generated by successively activated switches. The scale of a research facility on inertial fusion by hypervelocity impact can be reduced to that of a laboratory by using projectiles with a very small radius, of the order of 1 μm and bellow, when charge-to-mass ratio has more favorable values, and not by compressing the target at rest. The ratio of the energy released in fusion reactions to the energy of the incident projectile will in this case be much less than 1, but we still expect to see the increase of the fusion yield per incident nucleon with the radius of the projectile, which is the basic assumption of inertial impact fusion. (author)

Progress toward fusion with light ions

International Nuclear Information System (INIS)

1980-01-01

New results in target design, beam generation and transport, and pulse power technology have led to a program shift stressing light ion-driven inertial confinement fusion. According to present estimates, a gain ten fusion pellet will require at least one megajoule and approx. 100 TW power input. Progress in ion sources has resulted in beam power density of approx. 1 TW/cm 2 , a factor of ten increase over the last year, and cylindrical implosion experiments have been performed. Other experiments have demonstrated the ability to transport ion and electron beams with high efficiency and have confirmed numerical predictions on the properties of beam transport channels converging at a target. These developments together with improvements in pulse power technology allow us to project that the 72 beam, 100 TW Particle Beam Fusion Accelerator, PBFA-II will attain target output energy equal to stored energy in the accelerator

Fusion Revisits CERN

CERN Multimedia

2001-01-01

It's going to be a hot summer at CERN. At least in the Main Building, where from 13 July to 20 August an exhibition is being hosted on nuclear fusion, the energy of the Stars. Nuclear fusion is the engine driving the stars but also a potential source of energy for mankind. The exhibition shows the different nuclear fusion techniques and research carried out on the subject in Europe. Inaugurated at CERN in 1993, following collaboration between Lausanne's CRPP-EPFL and CERN, with input from Alessandro Pascolini of Italy's INFN, this exhibition has travelled round Europe before being revamped and returning to CERN. 'Fusion, Energy of the Stars', from 13 July onwards, Main Building

Some implications for mirror research of the coupling between fusion economics and fusion physics

International Nuclear Information System (INIS)

Post, R.F.

1980-01-01

The thesis is made that physics understanding and innovation represent two of the most important ingredients of any program to develop fusion power. In this context the coupling between these and the econmics of yet-to-be realized fusion power plants is explored. The coupling is two-way: realistic evaluations of the economic (and environmental) requirements for fusion power systems can influence the physics objectives of present-day fusion research programs; physics understanding and innovative ideas can favorably impact the future economics of fusion power systems. Of equal importance is the role that physics/innovation can have on the time scale for the first practical demonstration of fusion power. Given the growing worldwide need for long-term solutions to the problem of energy it is claimed to be crucial that fusion research be carried out on a broad base and in a spirit that both facilitates the growth of physics understanding and fosters innovation. Developing this theme, some examples of mirror-based fusion system concepts are given that illustrate the coupling here described

Tokamak Fusion Test Reactor D-T results

International Nuclear Information System (INIS)

Meade, D.M.

1995-01-01

Temperatures, densities and confinement of deuterium plasmas confined in tokamaks have been achieved within the last decade that are approaching those required for a D-T reactor. As a result, the unique phenomena present in a D-T reactor plasma (D-T plasma confinement, α confinement, α heating and possible α-driven instabilities) can now be studied in the laboratory. Recent experiments on the Tokamak Fusion Test Reactor (TFTR) have been the first magnetic fusion experiments to study plasmas with reactor fuel concentrations of tritium. The injection of about 20MW of tritium and 14MW of deuterium neutral beams into the TFTR produced a plasma with a T-to-D density ratio of about 1 and yielding a maximum fusion power of about 9.2MW. The fusion power density in the core of the plasma was about 1.8MWm -3 , approximating that expected in a D-T fusion reactor. A TFTR plasma with a T-to-D density ratio of about 1 was found to have about 20% higher energy confinement time than a comparable D plasma, indicating a confinement scaling with average ion mass A of τ E ∝A 0.6 . The core ion temperature increased from 30 to 37keV owing to a 35% improvement of ion thermal conductivity. Using the electron thermal conductivity from a comparable deuterium plasma, about 50% of the electron temperature increase from 9 to 10.6keV can be attributed to electron heating by the α particles. The approximately 5% loss of α particles, as observed on detectors near the bottom edge of the plasma, was consistent with classical first orbit loss without anomalous effects. Initial measurements have been made of the confined high energy α particles and the resultant α ash density. At fusion power levels of 7.5MW, fluctuations at the toroidal Alfven eigen-mode frequency were observed by the fluctuation diagnostics. However, no additional α loss due to the fluctuations was observed. (orig.)

50 years of fusion research

Science.gov (United States)

Meade, Dale

2010-01-01

Fusion energy research began in the early 1950s as scientists worked to harness the awesome power of the atom for peaceful purposes. There was early optimism for a quick solution for fusion energy as there had been for fission. However, this was soon tempered by reality as the difficulty of producing and confining fusion fuel at temperatures of 100 million °C in the laboratory was appreciated. Fusion research has followed two main paths—inertial confinement fusion and magnetic confinement fusion. Over the past 50 years, there has been remarkable progress with both approaches, and now each has a solid technical foundation that has led to the construction of major facilities that are aimed at demonstrating fusion energy producing plasmas.

The controlled thermonuclear fusion

International Nuclear Information System (INIS)

Barre, Bertrand

2014-01-01

After some generalities on particle physics, and on fusion and fission reactions, the author outlines that the fission reaction is easier to obtain than the fusion reaction, evokes the fusion which takes place in stars, and outlines the difficulty to manage and control this reaction: one of its application is the H bomb. The challenge is therefore to find a way to control this reaction and make it a steady and continuous source of energy. The author then presents the most promising way: the magnetic confinement fusion. He evokes its main issues, the already performed experiments (tokamak), and gives a larger presentation of the ITER project. Then, he evokes another way, the inertial confinement fusion, and the two main experimental installations (National Ignition Facility in Livermore, and the Laser Megajoule in Bordeaux). Finally, he gives a list of benefits and drawbacks of an industrial nuclear fusion

Synthetic fuels and fusion

Energy Technology Data Exchange (ETDEWEB)

Fillo, J A; Powell, J; Steinberg, M [Brookhaven National Lab., Upton, NY (USA)

1981-03-01

The decreasing availability of fossil fuels emphasizes the need to develop systems which will produce synthetic fuel to substitute for and supplement the natural supply. An important first step in the synthesis of liquid and gaseous fuels is the production of hydrogen. Thermonuclear fusion offers an inexhaustible source of energy for the production of hydrogen from water. Depending on design, electric generation efficiencies of approx. equal to 40-60% and hydrogen production efficiencies by high temperature electrolysis of approx. equal to 50-70% are projected for fusion reactors using high temperature blankets. Fusion/coal symbiotic systems appear economically promising for the first generation of commercial fusion synfuels plants. Coal production requirements and the environmental effects of large-scale coal usage would be greatly reduced by a fusion/coal system. In the long-term, there could be a gradual transition to an inexhaustible energy system based solely on fusion.

Adjacent level effects of bi level disc replacement, bi level fusion and disc replacement plus fusion in cervical spine--a finite element based study.

Science.gov (United States)

Faizan, Ahmad; Goel, Vijay K; Biyani, Ashok; Garfin, Steven R; Bono, Christopher M

2012-03-01

Studies delineating the adjacent level effect of single level disc replacement systems have been reported in literature. The aim of this study was to compare the adjacent level biomechanics of bi-level disc replacement, bi-level fusion and a construct having adjoining level disc replacement and fusion system. In total, biomechanics of four models- intact, bi level disc replacement, bi level fusion and fusion plus disc replacement at adjoining levels- was studied to gain insight into the effects of various instrumentation systems on cranial and caudal adjacent levels using finite element analysis (73.6N+varying moment). The bi-level fusion models are more than twice as stiff as compared to the intact model during flexion-extension, lateral bending and axial rotation. Bi-level disc replacement model required moments lower than intact model (1.5Nm). Fusion plus disc replacement model required moment 10-25% more than intact model, except in extension. Adjacent level motions, facet loads and endplate stresses increased substantially in the bi-level fusion model. On the other hand, adjacent level motions, facet loads and endplate stresses were similar to intact for the bi-level disc replacement model. For the fusion plus disc replacement model, adjacent level motions, facet loads and endplate stresses were closer to intact model rather than the bi-level fusion model, except in extension. Based on our finite element analysis, fusion plus disc replacement procedure has less severe biomechanical effects on adjacent levels when compared to bi-level fusion procedure. Bi-level disc replacement procedure did not have any adverse mechanical effects on adjacent levels. Copyright © 2011 Elsevier Ltd. All rights reserved.

Magnetic-fusion program

International Nuclear Information System (INIS)

1980-08-01

In February 1980, the Director of Energy Research requested that the Energy Research Advisory Board (ERAB) review the Department of Energy (DOE) Magnetic Fusion Program. Of particular concern to the DOE was the judicious choice of the next major steps toward demonstration of economic power production from fusion. Of equal concern was the overall soundness of the DOE Magnetic Fusion Program: its pace, scope, and funding profiles. Their finding and recommendations are included

Fusion safety data base

International Nuclear Information System (INIS)

Laats, E.T.; Hardy, H.A.

1983-01-01

The purpose of this Fusion Safety Data Base Program is to provide a repository of data for the design and development of safe commercial fusion reactors. The program is sponsored by the United States Department of Energy (DOE), Office of Fusion Energy. The function of the program is to collect, examine, permanently store, and make available the safety data to the entire US magnetic-fusion energy community. The sources of data will include domestic and foreign fusion reactor safety-related research programs. Any participant in the DOE Program may use the Data Base Program from his terminal through user friendly dialog and can view the contents in the form of text, tables, graphs, or system diagrams

Advanced fusion reactor

International Nuclear Information System (INIS)

Tomita, Yukihiro

2003-01-01

The main subjects on fusion research are now on D-T fueled fusion, mainly due to its high fusion reaction rate. However, many issues are still remained on the wall loading by the 14 MeV neutrons. In the case of D-D fueled fusion, the neutron wall loading is still remained, though the technology related to tritium breeding is not needed. The p- 6 Li and p- 11 B fueled fusions are not estimated to be the next generation candidate until the innovated plasma confinement technologies come in useful to achieve the high performance plasma parameters. The fusion reactor of D- 3 He fuels has merits on the smaller neutron wall loading and tritium handling. However, there are difficulties on achieving the high temperature plasma more than 100 keV. Furthermore the high beta plasma is needed to decrease synchrotron radiation loss. In addition, the efficiency of the direct energy conversion from protons coming out from fusion reaction is one of the key parameters in keeping overall power balance. Therefore, open magnetic filed lines should surround the plasma column. In this paper, we outlined the design of the commercial base reactor (ARTEMIS) of 1 GW electric output power configured by D- 3 He fueled FRC (Field Reversed Configuration). The ARTEMIS needs 64 kg of 3 He per a year. On the other hand, 1 million tons of 3 He is estimated to be in the moon. The 3 He of about 10 23 kg are to exist in gaseous planets such as Jupiter and Saturn. (Y. Tanaka)

Fusion research at Culham site

International Nuclear Information System (INIS)

Tolonen, P.; Toppila, T.

1998-01-01

One of the many targets on the Finnish Nuclear Society (ATS) excursion to England was the Culham fusion research site. The site has divided into two parts. One of them is UKAEA Fusion with small scale fusion reactors and 200 employees. UKAEA has 3 fusion reactors at Culham site. One of is the START (Small Tight Aspect Ratio Tokamak) which was operational since 1991 but is today already out of operation. UKAEA has been operating a JET-like tokamak fusion reactor COMPASS-D since 1989. The latest of three reactors is MAST (Mega Amp Spherical Tokamak), which is still under construction. The first plasma will take place in the end of 1998. Another part of Culham site is JET (Joint European Torus), an all-European fusion undertaking with 350 employees. 150 of them are from various European countries and the rest 200 are employed by UKAEA. JET is the biggest fusion reactor ever and it represents the latest step in world wide fusion programme. In October 1997 JET achieved a world record in fusion power and energy. JET produced 16,1 MW power for 1 s and totally 21,7 MJ energy. This is the closest attempt to achieve break-even conditions. The next step in world wide fusion programme will be international ITER-reactor. This undertaking has some financial problems, since United States has taken distance to magnetic fusion research and moved closer to inertial fusion with funding of US Department of Defence. The planned reactor, however, is physically twice as big as JET. The step after this phase will be DEMO, which is purposed to produce fusion energy. According to our hosts in Culham this phase is 40 years ahead. (author)

Assessment of ion kinetic effects in shock-driven inertial confinement fusion implosions using fusion burn imaging

International Nuclear Information System (INIS)

Rosenberg, M. J.; Séguin, F. H.; Rinderknecht, H. G.; Zylstra, A. B.; Li, C. K.; Sio, H.; Johnson, M. Gatu; Frenje, J. A.; Petrasso, R. D.; Amendt, P. A.; Wilks, S. C.; Pino, J.; Atzeni, S.; Hoffman, N. M.; Kagan, G.; Molvig, K.; Glebov, V. Yu.; Stoeckl, C.; Seka, W.; Marshall, F. J.

2015-01-01

The significance and nature of ion kinetic effects in D 3 He-filled, shock-driven inertial confinement fusion implosions are assessed through measurements of fusion burn profiles. Over this series of experiments, the ratio of ion-ion mean free path to minimum shell radius (the Knudsen number, N K ) was varied from 0.3 to 9 in order to probe hydrodynamic-like to strongly kinetic plasma conditions; as the Knudsen number increased, hydrodynamic models increasingly failed to match measured yields, while an empirically-tuned, first-step model of ion kinetic effects better captured the observed yield trends [Rosenberg et al., Phys. Rev. Lett. 112, 185001 (2014)]. Here, spatially resolved measurements of the fusion burn are used to examine kinetic ion transport effects in greater detail, adding an additional dimension of understanding that goes beyond zero-dimensional integrated quantities to one-dimensional profiles. In agreement with the previous findings, a comparison of measured and simulated burn profiles shows that models including ion transport effects are able to better match the experimental results. In implosions characterized by large Knudsen numbers (N K  ∼ 3), the fusion burn profiles predicted by hydrodynamics simulations that exclude ion mean free path effects are peaked far from the origin, in stark disagreement with the experimentally observed profiles, which are centrally peaked. In contrast, a hydrodynamics simulation that includes a model of ion diffusion is able to qualitatively match the measured profile shapes. Therefore, ion diffusion or diffusion-like processes are identified as a plausible explanation of the observed trends, though further refinement of the models is needed for a more complete and quantitative understanding of ion kinetic effects

Assessment of ion kinetic effects in shock-driven inertial confinement fusion implosions using fusion burn imaging

Energy Technology Data Exchange (ETDEWEB)

Rosenberg, M. J., E-mail: mros@lle.rochester.edu; Séguin, F. H.; Rinderknecht, H. G.; Zylstra, A. B.; Li, C. K.; Sio, H.; Johnson, M. Gatu; Frenje, J. A.; Petrasso, R. D. [Plasma Science and Fusion Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States); Amendt, P. A.; Wilks, S. C.; Pino, J. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Atzeni, S. [Dipartimento SBAI, Università di Roma “La Sapienza” and CNISM, Via A. Scarpa 14-16, I-00161 Roma (Italy); Hoffman, N. M.; Kagan, G.; Molvig, K. [Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Glebov, V. Yu.; Stoeckl, C.; Seka, W.; Marshall, F. J. [Laboratory for Laser Energetics, University of Rochester, Rochester, New York 14623 (United States); and others

2015-06-15

The significance and nature of ion kinetic effects in D{sup 3}He-filled, shock-driven inertial confinement fusion implosions are assessed through measurements of fusion burn profiles. Over this series of experiments, the ratio of ion-ion mean free path to minimum shell radius (the Knudsen number, N{sub K}) was varied from 0.3 to 9 in order to probe hydrodynamic-like to strongly kinetic plasma conditions; as the Knudsen number increased, hydrodynamic models increasingly failed to match measured yields, while an empirically-tuned, first-step model of ion kinetic effects better captured the observed yield trends [Rosenberg et al., Phys. Rev. Lett. 112, 185001 (2014)]. Here, spatially resolved measurements of the fusion burn are used to examine kinetic ion transport effects in greater detail, adding an additional dimension of understanding that goes beyond zero-dimensional integrated quantities to one-dimensional profiles. In agreement with the previous findings, a comparison of measured and simulated burn profiles shows that models including ion transport effects are able to better match the experimental results. In implosions characterized by large Knudsen numbers (N{sub K} ∼ 3), the fusion burn profiles predicted by hydrodynamics simulations that exclude ion mean free path effects are peaked far from the origin, in stark disagreement with the experimentally observed profiles, which are centrally peaked. In contrast, a hydrodynamics simulation that includes a model of ion diffusion is able to qualitatively match the measured profile shapes. Therefore, ion diffusion or diffusion-like processes are identified as a plausible explanation of the observed trends, though further refinement of the models is needed for a more complete and quantitative understanding of ion kinetic effects.

Tritium-assisted fusion breeders

International Nuclear Information System (INIS)

Greenspan, E.; Miley, G.H.

1983-08-01

This report undertakes a preliminary assessment of the prospects of tritium-assisted D-D fuel cycle fusion breeders. Two well documented fusion power reactor designs - the STARFIRE (D-T fuel cycle) and the WILDCAT (Cat-D fuel cycle) tokamaks - are converted into fusion breeders by replacing the fusion electric blankets with 233 U producing fission suppressed blankets; changing the Cat-D fuel cycle mode of operation by one of the several tritium-assisted D-D-based modes of operation considered; adjusting the reactor power level; and modifying the resulting plant cost to account for the design changes. Three sources of tritium are considered for assisting the D-D fuel cycle: tritium produced in the blankets from lithium or from 3 He and tritium produced in the client fission reactors. The D-D-based fusion breeders using tritium assistance are found to be the most promising economically, especially the Tritium Catalyzed Deuterium mode of operation in which the 3 He exhausted from the plasma is converted, by neutron capture in the blanket, into tritium which is in turn fed back to the plasma. The number of fission reactors of equal thermal power supported by Tritium Catalyzed Deuterium fusion breeders is about 50% higher than that of D-T fusion breeders, and the profitability is found to be slightly lower than that of the D-T fusion breeders

Fusion neutronics plan in the development of fusion reactor. With the aim of realizing electric power

Energy Technology Data Exchange (ETDEWEB)

Nakamura, Hiroo; Morimoto, Yuichi; Ochiai, Kentarou; Sugimoto, Masayoshi; Nishitani, Takeo; Takeuchi, Hiroshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

2000-10-01

On June 1992, Atomic Energy Commission in Japan has settled Third Phase Program of Fusion Research and Development to achieve self-ignition condition, to realize long pulse burning plasma and to establish basis of fusion engineering for demonstration reactor. This report describes research plan of Fusion Neutron Laboratory in JAERI toward a development of fusion reactor with an aim of realizing electric power. The fusion neutron laboratory has a fusion neutronics facility (FNS), intense fusion neutron source. The plan includes research items in the FNS; characteristics of shielding and breeding materials, nuclear characteristics of materials, fundamental irradiation process of insulator, diagnostics materials and structural materials, and development of in-vessel diagnostic technology. Upgrade of the FNS is also described. Also, the International Fusion Material Irradiation Facility (IFMIF) for intense neutron source to develop fusion materials is described. (author)

Fluorescent S-layer fusion proteins

International Nuclear Information System (INIS)

Kainz, B.

2010-01-01

This work describes the construction and characterisation of fluorescent S-layer fusion proteins used as building blocks for the fabrication of nanostructured monomolecular biocoatings on silica particles with defined fluorescence properties. The S-layer protein SgsE of Geobacillus stearothermophilus NRS 2004/3a was fused with the pH-dependant cyan, green and yellow variant of the green fluorescent protein (GFP) and the red fluorescent protein mRFP1. These fluorescent S-layer fusion proteins, acting as scaffold and optical sensing element simultaneously, were able to reassemble in solution and on silica particles forming 2D nanostructures with p2 lattice symmetry (a=11 ±0.5 nm, b=14 ±0.4 nm, g=80 ±1 o ). The pH-dependant fluorescence behaviour was studied with fluorimetry, confocal microscopy and flow cytometry. These fluorescent S-layer fusion proteins can be used as pH-sensor. 50% of the fluorescence intensity decreases at their calculated pKa values (pH6 - pH5). The fluorescence intensity of the GFP variants vanished completely between pH4 and pH3 whereas the chromophore of the red protein mRFP1 was only slightly affected in acidic conditions. At the isoelectric point of the S-layer coated silica particles (pH4.6 ±0.2) an increase in particle aggregation was detected by flow cytometry. The cyan and yellow fluorescent proteins were chosen to create a bi-fluorescent S-layer tandem fusion protein with the possibility for resonance energy transfer (FRET). A transfer efficiency of 20% and a molecular distance between the donor (ECFP) and acceptor (YFP) chromophores of around 6.2 nm could be shown. This bi-fluorescent ECFP-SgsE-YFP tandem fusion protein was able to reassemble on solid surfaces. The remarkable combination of fluorescence and self-assembly and the design of bi-functional S-layer tandem fusion protein matrices makes them to a promising tool in nanobiotechnology. (author) [de

Quasi-elastic scattering an alternative tool for mapping the fusion barriers for heavy-ion induced fusion reaction

International Nuclear Information System (INIS)

Behera, B.R.

2016-01-01

Heavy element synthesis through heavy-ion induced fusion reaction is an active field in contemporary nuclear physics. Exact knowledge of fusion barrier is one of the essential parameters for planning any experiments for heavy element production. Theoretically there are many models available to predict the exact barrier. Though these models are successful for predicting the fusion of medium mass nuclei, it somehow fails for predicting the exact location of barrier for fusion of heavy nuclei. Experimental determination of barrier for such reactions is required for future experiments for the synthesis of heavy elements. Traditionally fusion barrier is determined taking a double derivative of fusion excitation function. However, such method is difficult in case of fusion of heavy nuclei due to its very low fusion/capture cross section and its experimental complications. Alternatively fusion barrier can be determined by measuring the quasi-elastic cross section at backward angles. This method can be applied for determining the fusion barrier for the fusion of heavy nuclei. Experimental determination of fusion barrier by different methods and comparison of the fusion excitation function and quasi-elastic scattering methods for the determination of fusion barrier are reviewed. At IUAC, New Delhi recently a program has been started for the measurement of fusion barrier through quasi-elastic scattering methods. The experimental facility and the first results of the experiments carried out with this facility are presented. (author)

Cluster expression in fission and fusion in high-dimensional macroscopic-microscopic calculations

International Nuclear Information System (INIS)

Iwamoto, Akira; Ichikawa, Takatoshi; Moller, Peter; Sierk, Arnold J.

2004-01-01

We discuss the relation between the fission-fusion potential-energy surfaces of very heavy nuclei and the formation process of these nuclei in cold-fusion reactions. In the potential-energy surfaces, we find a pronounced valley structure, with one valley corresponding to the cold-fusion reaction, the other to fission. As the touching point is approached in the cold-fusion entrance channel, an instability towards dynamical deformation of the projectile occurs, which enhances the fusion cross section. These two 'cluster effects' enhance the production of superheavy nuclei in cold-fusion reactions, in addition to the effect of the low compound-system excitation energy in these reactions. Heavy-ion fusion reactions have been used extensively to synthesize heavy elements beyond actinide nuclei. In order to proceed further in this direction, we need to understand the formation process more precisely, not just the decay process. The dynamics of the formation process are considerably more complex than the dynamics necessary to interpret the spontaneous-fission decay of heavy elements. However, before implementing a full dynamical description it is useful to understand the basic properties of the potential-energy landscape encountered in the initial stages of the collision. The collision process and entrance-channel landscape can conveniently be separated into two parts, namely the early-stage separated system before touching and the late-stage composite system after touching. The transition between these two stages is particularly important, but not very well understood until now. To understand better the transition between the two stages we analyze here in detail the potential energy landscape or 'collision surface' of the system both outside and inside the touching configuration of the target and projectile. In Sec. 2, we discuss calculated five-dimensional potential-energy landscapes inside touching and identify major features. In Sec. 3, we present calculated

Multisensor data fusion algorithm development

Energy Technology Data Exchange (ETDEWEB)

Yocky, D.A.; Chadwick, M.D.; Goudy, S.P.; Johnson, D.K.

1995-12-01

This report presents a two-year LDRD research effort into multisensor data fusion. We approached the problem by addressing the available types of data, preprocessing that data, and developing fusion algorithms using that data. The report reflects these three distinct areas. First, the possible data sets for fusion are identified. Second, automated registration techniques for imagery data are analyzed. Third, two fusion techniques are presented. The first fusion algorithm is based on the two-dimensional discrete wavelet transform. Using test images, the wavelet algorithm is compared against intensity modulation and intensity-hue-saturation image fusion algorithms that are available in commercial software. The wavelet approach outperforms the other two fusion techniques by preserving spectral/spatial information more precisely. The wavelet fusion algorithm was also applied to Landsat Thematic Mapper and SPOT panchromatic imagery data. The second algorithm is based on a linear-regression technique. We analyzed the technique using the same Landsat and SPOT data.

LiWall Fusion - The New Concept of Magnetic Fusion

International Nuclear Information System (INIS)

Zakharov, L.E.

2011-01-01

Utilization of the outstanding abilities of a liquid lithium layer in pumping hydrogen isotopes leads to a new approach to magnetic fusion, called the LiWall Fusion. It relies on innovative plasma regimes with low edge density and high temperature. The approach combines fueling the plasma by neutral injection beams with the best possible elimination of outside neutral gas sources, which cools down the plasma edge. Prevention of cooling the plasma edge suppresses the dominant, temperature gradient related turbulence in the core. Such an approach is much more suitable for controlled fusion than the present practice, relying on high heating power for compensating essentially unlimited turbulent energy losses.

Why and how of fusion

International Nuclear Information System (INIS)

Miley, G.H.

1977-01-01

The potential advantages of fusion power are listed. The approaches to plasma containment are mentioned and the status of the fusion program is described. The ERDA and EPRI programs are discussed. The Fusion Energy Foundation's activities are mentioned. Fusion research at the U. of Ill. is described briefly

Fusion Canada issue 25

International Nuclear Information System (INIS)

1994-08-01

A short bulletin from the National Fusion Program highlighting in this issue an economic impact study of the Canadian site for ITER, Harvey Skarsgard: fusion pioneer retires, NFP: Phillips and Holtslander exchange roles, Europe's fusion funding proposals and an update of CCFM/TdeV. 1 fig

Fusion cost normalization

International Nuclear Information System (INIS)

Schulte, S.C.; Willke, T.L.

1978-01-01

The categorization and accounting methods described in this paper provide a common format that can be used to assess the economic character of magnetically confined fusion reactor design concepts. The format was developed with assistance from the fusion economics community, thus ensuring that the methods meet with the approval of potential users. The format will aid designers in the preparation of design concept cost estimates and also provide policy makers with a tool to assist in appraising which design concepts may be economically promising. Adherence to the format when evaluating prospective fusion reactor design concepts will result in the identification of the more promising concepts, thus enabling the fusion power alternatives with better economic potential to be quickly and efficiently developed

A Plan for the Development of Fusion Energy. Final Report to Fusion Energy Sciences Advisory Committee, Fusion Development Path Panel

Energy Technology Data Exchange (ETDEWEB)

None, None

2003-03-05

This report presents a plan for the deployment of a fusion demonstration power plant within 35 years, leading to commercial application of fusion energy by mid-century. The plan is derived from the necessary features of a demonstration fusion power plant and from the time scale defined by President Bush. It identifies critical milestones, key decision points, needed major facilities and required budgets.

Muon-catalyzed fusion revisited

Energy Technology Data Exchange (ETDEWEB)

Anon.

1984-12-15

A negative muon can induce nuclear fusion in the reaction of deuteron and triton nuclei giving a helium nucleus, a neutron and an emerging negative muon. The muon forms a tightlybound deuteron-triton-muon molecule and fusion follows in about 10{sup -12}s. Then the muon is free again to induce further reactions. Thus the muon can serve as a catalyst for nuclear fusion, which can proceed without the need for the high temperatures which are needed in the confinement and inertial fusion schemes. At room temperature, up to 80 fusions per muon have recently been observed at the LAMPF machine at Los Alamos, and it is clear that this number can be exceeded. These and other results were presented at a summer Workshop on Muon-Catalyzed Fusion held in Jackson, Wyoming. Approximately fifty scientists attended from Austria, Canada, India, Italy, Japan, South Africa, West Germany, and the United States. The Workshop itself is symbolic of the revival of interest in this subject.

A neutron poison tritium breeding controller applied to a water cooled fusion reactor model

International Nuclear Information System (INIS)

Morgan, L.W.G.; Packer, L.W.

2014-01-01

the water coolant of a stratified blanket model, depending on the difference between the required tritium excess inventory and the measured tritium excess inventory. The compounds effectively reduce the amount of low energy neutrons available to react with lithium compounds, thus reducing the tritium breeding ratio. This controller reduces the amount of tritium being produced at the start of the reactor's lifetime and increases the rate of tritium production towards the end of its lifetime. Thus, a relatively stable tritium production level may be maintained, allowing the control system to minimize the stored tritium with obvious safety benefits. The FATI code (Fusion Activation and Transport Interface) will be used to perform the tritium breeding and controller calculations

A neutron poison tritium breeding controller applied to a water cooled fusion reactor model

Energy Technology Data Exchange (ETDEWEB)

Morgan, L.W.G., E-mail: Lee.Morgan@CCFE.ac.uk; Packer, L.W.

2014-10-15

the water coolant of a stratified blanket model, depending on the difference between the required tritium excess inventory and the measured tritium excess inventory. The compounds effectively reduce the amount of low energy neutrons available to react with lithium compounds, thus reducing the tritium breeding ratio. This controller reduces the amount of tritium being produced at the start of the reactor's lifetime and increases the rate of tritium production towards the end of its lifetime. Thus, a relatively stable tritium production level may be maintained, allowing the control system to minimize the stored tritium with obvious safety benefits. The FATI code (Fusion Activation and Transport Interface) will be used to perform the tritium breeding and controller calculations.

Fusion events

International Nuclear Information System (INIS)

Aboufirassi, M; Angelique, J.C.; Bizard, G.; Bougault, R.; Brou, R.; Buta, A.; Colin, J.; Cussol, D.; Durand, D.; Genoux-Lubain, A.; Horn, D.; Kerambrun, A.; Laville, J.L.; Le Brun, C.; Lecolley, J.F.; Lefebvres, F.; Lopez, O.; Louvel, M.; Meslin, C.; Metivier, V.; Nakagawa, T.; Peter, J.; Popescu, R.; Regimbart, R.; Steckmeyer, J.C.; Tamain, B.; Vient, E.; Wieloch, A.; Yuasa-Nakagawa, K.

1998-01-01

The fusion reactions between low energy heavy ions have a very high cross section. First measurements at energies around 30-40 MeV/nucleon indicated no residue of either complete or incomplete fusion, thus demonstrating the disappearance of this process. This is explained as being due to the high amount o energies transferred to the nucleus, what leads to its total dislocation in light fragments and particles. Exclusive analyses have permitted to mark clearly the presence of fusion processes in heavy systems at energies above 30-40 MeV/nucleon. Among the complete events of the Kr + Au reaction at 60 MeV/nucleon the majority correspond to binary collisions. Nevertheless, for the most considerable energy losses, a class of events do occur for which the detected fragments appears to be emitted from a unique source. These events correspond to an incomplete projectile-target fusion followed by a multifragmentation. Such events were singled out also in the reaction Xe + Sn at 50 MeV/nucleon. For the events in which the energy dissipation was maximal it was possible to isolate an isotropic group of events showing all the characteristics of fusion nuclei. The fusion is said to be incomplete as pre-equilibrium Z = 1 and Z = 2 particles are emitted. The cross section is of the order of 25 mb. Similar conclusions were drown for the systems 36 Ar + 27 Al and 64 Zn + nat Ti. A cross section value of ∼ 20 mb was determined at 55 MeV/nucleon in the first case, while the measurement of evaporation light residues in the last system gave an upper limit of 20-30 mb for the cross section at 50 MeV/nucleon

Conference on Norwegian fusion research

International Nuclear Information System (INIS)

The question of instituting a systematic research programme in Norway on aspects of thermonuclear and plasma physics has been raised. The conference here reported was intended to provide basic information on the status of fusion research internationally and to discuss a possible Norwegian programme. The main contributions covered the present status of fusion research, international cooperation, fusion research in small countries and minor laboratories, fusion research in Denmark and Sweden, and a proposed fusion experiment in Bergen. (JIW)

Nuclear fusion power

International Nuclear Information System (INIS)

Dinghee, D.A.

1983-01-01

In this chapter, fusion is compared with other inexhaustible energy sources. Research is currently being conducted both within and outside the USA. The current confinement principles of thermonuclear reactions are reveiwed with the discussion of economics mainly focusing on the magnetic confinement concepts. Environmental, health and safety factors are of great concern to the public and measures are being taken to address them. The magnetic fusion program logic and the inertial fusion program logic are compared

Influence of mass asymmetry in fusion cross section of intermediate weight ions

International Nuclear Information System (INIS)

Anjos, R.M. dos.

1987-01-01

The mass asymmetry degree effect on fusion, was investigated for different systems involving nucleus A projectie , A target ≤ 40, populating a compound nucleus. The following systems were studied: ( 19 F + 19 F), ( 12 C + 26 Mg) and ( 19 F + 12 C, 16 O, 27 Al, 40 Ca) in the energy range of 32 ≤ E lab ≤ 72 MeV and angular range 6 0 ≤ Θ lab ≤ 28 0 . The experimental method employed the time of flight technique, of the evaporation residuals. Analysis of excitation function indicate different behavior for symmetric and asymmetric systems suggesting that the presence of other more competitive processes is more pronounced in asymmetric entrance channels at high energies. These behaviors indicate that mass asymmetry is an important point in complete and incomplete fusion processes. (A.C.A.S.) [pt

Effects of molecular weight of PVA on formation, stability and deformation of compound droplets for ICF polymer shells

Science.gov (United States)

Liu, Meifang; Zheng, Yueqing; Li, Jie; Chen, Sufen; Liu, Yiyang; Li, Jing; Li, Bo; Zhang, Zhanwen

2017-01-01

Sphericity and wall thickness uniformity are some of the hardest specifications to fulfill, as required by inertial confined fusion (ICF) research for polymer shells prepared by the microencapsulation technique. Driven by the need to control the deformation of compound droplets, the effects of the molecular weight of poly(vinyl alcohol) (PVA) on the formation and stability of the droplets, as well as the sphericity and wall thickness uniformity of the resulting shells, were investigated. On increasing the molecular weight of the PVA, the densities of the external water phases (W2) are almost the same, but the viscosity of the W2 phase increases more quickly than the interfacial tension. This makes the detaching force increase more quickly than the upward one, causing the formation of compound droplets and detachment from the oil tube. On the other hand, the increase in interfacial tension makes the maximum pressures ( P max) in the O phase (O) of the compound droplets increase, causing them to rupture easily and decreasing their stability. However, for PVA with the same molecular weight, the viscous shear force in the flowing field reduces the role of gravity and makes the inner water droplet move towards the center of the compound droplet, decreasing its P max in the flowing field and improving its stability. Moreover, during the solidifying process, the viscous shear force increases more quickly than the interfacial tension force due to the quicker increase in viscosity with an increase in the molecular weight of the PVA. The increase in the viscous shear force can make the droplets deform, resulting in a decrease in their sphericity. However, the appropriate viscous shear force can also center the compound droplet—although they become decentered when the viscous shear force is too large, leading to the wall thickness uniformity increasing at first before decreasing quickly. The results presented in this work provide a more in-depth understanding of the

Coatings for fusion reactor environments

International Nuclear Information System (INIS)

Mattox, D.M.

1979-01-01

The internal surfaces of a tokamak fusion reactor control the impurity injection and gas recycling into the fusion plasma. Coating of internal surfaces may provide a desirable and possibly necessary design flexibility for achieving the temperatures, ion densities and containment times necessary for net energy production from fusion reactions to take place. In this paper the reactor environments seen by various componentare reviewed along with possible materials responses. Characteristics of coating-substrate systems, important to fusion applications, are delineated and the present status of coating development for fusion applications is reviewed. Coating development for fusion applications is just beginning and poses a unique and important challenge for materials development

Gene Fusion Markup Language: a prototype for exchanging gene fusion data.

Science.gov (United States)

Kalyana-Sundaram, Shanker; Shanmugam, Achiraman; Chinnaiyan, Arul M

2012-10-16

An avalanche of next generation sequencing (NGS) studies has generated an unprecedented amount of genomic structural variation data. These studies have also identified many novel gene fusion candidates with more detailed resolution than previously achieved. However, in the excitement and necessity of publishing the observations from this recently developed cutting-edge technology, no community standardization approach has arisen to organize and represent the data with the essential attributes in an interchangeable manner. As transcriptome studies have been widely used for gene fusion discoveries, the current non-standard mode of data representation could potentially impede data accessibility, critical analyses, and further discoveries in the near future. Here we propose a prototype, Gene Fusion Markup Language (GFML) as an initiative to provide a standard format for organizing and representing the significant features of gene fusion data. GFML will offer the advantage of representing the data in a machine-readable format to enable data exchange, automated analysis interpretation, and independent verification. As this database-independent exchange initiative evolves it will further facilitate the formation of related databases, repositories, and analysis tools. The GFML prototype is made available at http://code.google.com/p/gfml-prototype/. The Gene Fusion Markup Language (GFML) presented here could facilitate the development of a standard format for organizing, integrating and representing the significant features of gene fusion data in an inter-operable and query-able fashion that will enable biologically intuitive access to gene fusion findings and expedite functional characterization. A similar model is envisaged for other NGS data analyses.

POSTERIOR LUMBAR INTERBODY FUSION AND INSTRUMENTED POSTEROLATERAL FUSION IN ADULT SPONDYLOLISTHESIS: ASSESSMENT AND CLINICAL OUTCOME

Directory of Open Access Journals (Sweden)

Rajarajan

2015-11-01

Full Text Available OBJECTIVE: Aim of this study is to assess and compare the outcomes of posterior lumbar interbody fusion (PLIF and posterolateral fusion (PLF in adult isthmic spondylosthesis. BACKGROUND: Posterolateral fusion has been considered the best method and widely been used for surgical treatment of adult spondylolisthesis.Superior results have subsequently been reported with interbody fusion with cages and posterior instrumentation MATERIALS AND METHODS: Thirty six patients with isthmic spondylolisthesis were operated. One group (20 patients had decompression and posterolateral fusion (PLF with a pedicle screw system; other group (16 patients was treated by decompression, posterior lumbar interbody fusion (PLIF and a Pedicle screw system. In both groups adequate decompression was done RESULTS: Seventy seven percent of the patients had a good result with (PLIF and 68 percent with posterolateral fusion (PLF. However there was no statistical difference in cases with low grade slipping, whereas the difference was significant for cases with high grade slipping. Fusion rate was 93% with (PLIF and 68% with (PLF, but without any significant incidence in the functional outcome. 78% has relief of sciatica and neurogenic claudication. CONCLUSION: Based on these findings we found that for high grade spondylolisthesis which requires reduction or if the disc space is still high posterior lumbar inter body fusion is preferable. For low grade spondylolisthesis or if the disc space is narrow posterolateral fusion is preferable. A successful result of fusion operation depends on adequate decompression which relieves radicular symptoms.

Cell fusion in tumor progression: the isolation of cell fusion products by physical methods

Directory of Open Access Journals (Sweden)

Vincitorio Massimo

2011-09-01

Full Text Available Abstract Background Cell fusion induced by polyethylene glycol (PEG is an efficient but poorly controlled procedure for obtaining somatic cell hybrids used in gene mapping, monoclonal antibody production, and tumour immunotherapy. Genetic selection techniques and fluorescent cell sorting are usually employed to isolate cell fusion products, but both procedures have several drawbacks. Results Here we describe a simple improvement in PEG-mediated cell fusion that was obtained by modifying the standard single-step procedure. We found that the use of two PEG undertreatments obtains a better yield of cell fusion products than the standard method, and most of these products are bi- or trinucleated polykaryocytes. Fusion rate was quantified using fluorescent cell staining microscopy. We used this improved cell fusion and cell isolation method to compare giant cells obtained in vitro and giant cells obtained in vivo from patients with Hodgkin's disease and erythroleukemia. Conclusions In the present study we show how to improve PEG-mediated cell fusion and that cell separation by velocity sedimentation offers a simple alternative for the efficient purification of cell fusion products and to investigate giant cell formation in tumor development.

ITER implementation and fusion energy research in China

International Nuclear Information System (INIS)

Zhao, Jing; Feng, Zhaoliang; Yang, Changchun

2015-01-01

ITER Project is jointly implemented by China, EU, India, Japan, Korea, Russian Federation and USA, under the coordination of Center Team of ITER International Fusion Energy Organization (IO-CT). Chinese fusion research related institutes and industrial enterprises are fully involved in the implementation of China contribution to the project under the leadership of ITER China Domestic Agency (CN-DA), together with IO-CT. The progresses of Procurement Packages (PA) allocated to China and the technical issues, especially on key technology development and schedule, QA/QC issues, are highlighted in this report. The specific enterprises carrying out different PAs are identified in order to make the increasing international manufactures and producers to ITER PAs know each other well for the successful implementation of ITER project. The participation of China to the management of IO-CT is also included, mainly from the governmental aspect and staff recruited from China. On the other hand, the domestic fusion researches, including upgrade of EAST, HL-2A Tokamaks in China, TBM program, the next step design activities for fusion energy power plant, namely, CFETR and training in this area, are also introduced for global cooperation for international fusion community. (author)

Materials research and development for fusion energy applications

International Nuclear Information System (INIS)

Zinkle, S.J.; Snead, L.L.

1998-01-01

Some of the critical issues associated with materials selection for proposed magnetic fusion reactors are reviewed, with a brief overview of refractory alloys (vanadium, tantalum, molybdenum, tungsten) and primary emphasis on ceramic materials. SiC/SiC composites are under consideration for the first wall and blanket structure, and dielectric insulators will be used for the heating, control and diagnostic measurement of the fusion plasma. Key issues for SiC/SiC composites include radiation-induced degradation in the strength and thermal conductivity. Recent work has focused on the development of radiation-resistant fibers and fiber/matrix interfaces (porous SiC, SiC multilayers) which would also produce improved SiC/SiC performance for applications such as heat engines and aerospace components. The key physical parameters for dielectrics include electrical conductivity, dielectric loss tangent and thermal conductivity. Ionizing radiation can increase the electrical conductivity of insulators by many orders of magnitude, and surface leakage currents can compromise the performance of some fusion energy components. Irradiation can cause a pronounced degradation in the loss tangent and thermal conductivity. Fundamental physical parameter measurements on ceramics which are of interest for both fusion and non-fusion applications are discussed

Fusion of Nonionic Vesicles

DEFF Research Database (Denmark)

Bulut, Sanja; Oskolkova, M. Z.; Schweins, R.

2010-01-01

We present an experimental study of vesicle fusion using light and neutron scattering to monitor fusion events. Vesicles are reproducibly formed with an extrusion procedure using an single amphiphile triethylene glycol mono-n-decyl ether in water. They show long-term stability for temperatures ar...... a barrier to fusion changing from 15 k(B)T at T = 26 degrees C to 10k(H) T at T = 35 degrees C. These results are compatible with the theoretical predictions using the stalk model of vesicle fusion....

Nuclear fusion: The issues

International Nuclear Information System (INIS)

Griffin, R.D.

1993-01-01

The taming of fusion energy, has proved one of the most elusive quests of modern science. For four decades, the United States has doggedly pursued energy's holy grail, pumping more than $9 billion into research and reactor prototypes. This year, the federal government is slated to spend $339 million on fusion, more than the combined amount the government will spend for research on oil, natural gas, solar power, wind power, geothermal energy, biofuels and conservation. This article summarizes the technical, political in terms of international cooperation, economic, planning, etc. issues surrounding the continued development of fusion as a possible power source for the next century. Brief descriptions of how fusion works and of the design of a tokamak fusion machine are included

Munc18b Increases Insulin Granule Fusion, Restoring Deficient Insulin Secretion in Type-2 Diabetes Human and Goto-Kakizaki Rat Islets with Improvement in Glucose Homeostasis

Directory of Open Access Journals (Sweden)

Tairan Qin

2017-02-01

Infusion of Ad-Munc18b into GK rat pancreas led to sustained improvement in glucose homeostasis. However, Munc18b overexpression in normal islets increased only newcomer SG fusion. Therefore, Munc18b could potentially be deployed in human T2D to rescue the deficient GSIS.

Heat transfer in inertial confinement fusion reactor systems

International Nuclear Information System (INIS)

Hovingh, J.

1979-01-01

The transfer of energy produced by the interaction of the intense pulses of short-ranged fusion microexplosion products with materials is one of the most difficult problems in inertially-confined fusion (ICF) reactor design. The short time and deposition distance for the energy results in local peak power densities on the order of 10 18 watts/m 3 . High local power densities may cause change of state or spall in the reactor materials. This will limit the structure lifetimes for ICF reactors of economic physical sizes, increasing operating costs including structure replacement and radioactive waste management. Four basic first wall protection methods have evolved: a dry-wall, a wet-wall, a magnetically shielded wall, and a fluid wall. These approaches are distinguished by the way the reactor wall interfaces with fusion debris as well as the way the ambient cavity conditions modify the fusion energy forms and spectra at the first wall. Each of these approaches requires different heat transfer considerations

Increases thermal stability and cellulose-binding capacity of Cryptococcus sp. S-2 lipase by fusion of cellulose binding domain derived from Trichoderma reesei

International Nuclear Information System (INIS)

Thongekkaew, Jantaporn; Ikeda, Hiroko; Iefuji, Haruyuki

2012-01-01

Highlights: ► The CSLP and fusion enzyme were successfully expressed in the Pichia pastoris. ► The fusion enzyme was stable at 80 °C for 120-min. ► The fusion enzyme was responsible for cellulose-binding capacity. ► The fusion enzyme has an attractive applicant for enzyme immobilization. -- Abstract: To improve the thermal stability and cellulose-binding capacity of Cryptococcus sp. S-2 lipase (CSLP), the cellulose-binding domain originates from Trichoderma reesei cellobiohydrolase I was engineered into C-terminal region of the CSLP (CSLP-CBD). The CSLP and CSLP-CBD were successfully expressed in the Pichia pastoris using the strong methanol inducible alcohol oxidase 1 (AOX1) promoter and the secretion signal sequence from Saccharomyces cerevisiae (α factor). The recombinant CSLP and CSLP-CBD were secreted into culture medium and estimated by SDS–PAGE to be 22 and 27 kDa, respectively. The fusion enzyme was stable at 80 °C and retained more than 80% of its activity after 120-min incubation at this temperature. Our results also found that the fusion of fungal exoglucanase cellulose-binding domain to CSLP is responsible for cellulose-binding capacity. This attribute should make it an attractive applicant for enzyme immobilization.

Increases thermal stability and cellulose-binding capacity of Cryptococcus sp. S-2 lipase by fusion of cellulose binding domain derived from Trichoderma reesei

Energy Technology Data Exchange (ETDEWEB)

Thongekkaew, Jantaporn, E-mail: jantaporn_25@yahoo.com [Department of Biological Science, Faculty of Science, Ubon-Ratchathani University, Warinchumrab, Ubon-Ratchathani 34190 (Thailand); Ikeda, Hiroko; Iefuji, Haruyuki [Application Research Division, National Research Institute of Brewing, 3-7-1 Kagamiyama, Higashi-Hiroshima 739-0046 (Japan)

2012-03-30

Highlights: Black-Right-Pointing-Pointer The CSLP and fusion enzyme were successfully expressed in the Pichia pastoris. Black-Right-Pointing-Pointer The fusion enzyme was stable at 80 Degree-Sign C for 120-min. Black-Right-Pointing-Pointer The fusion enzyme was responsible for cellulose-binding capacity. Black-Right-Pointing-Pointer The fusion enzyme has an attractive applicant for enzyme immobilization. -- Abstract: To improve the thermal stability and cellulose-binding capacity of Cryptococcus sp. S-2 lipase (CSLP), the cellulose-binding domain originates from Trichoderma reesei cellobiohydrolase I was engineered into C-terminal region of the CSLP (CSLP-CBD). The CSLP and CSLP-CBD were successfully expressed in the Pichia pastoris using the strong methanol inducible alcohol oxidase 1 (AOX1) promoter and the secretion signal sequence from Saccharomyces cerevisiae ({alpha} factor). The recombinant CSLP and CSLP-CBD were secreted into culture medium and estimated by SDS-PAGE to be 22 and 27 kDa, respectively. The fusion enzyme was stable at 80 Degree-Sign C and retained more than 80% of its activity after 120-min incubation at this temperature. Our results also found that the fusion of fungal exoglucanase cellulose-binding domain to CSLP is responsible for cellulose-binding capacity. This attribute should make it an attractive applicant for enzyme immobilization.

Fast power cycle for fusion reactors

International Nuclear Information System (INIS)

Powell, J.; Fillo, J.; Makowitz, H.

1978-01-01

The unique, deep penetration capability of 14 MeV neutrons produced in DT fusion reactions allows the generation of very high temperature working fluid temperatures in a thermal power cycle. In the FAST (Fusion Augmented Steam Turbine) power cycle steam is directly superheated by the high temperature ceramic refractory interior of the blanket, after being generated by heat extracted from the relatively cool blanket structure. The steam is then passed to a high temperature gas turbine for power generation. Cycle studies have been carried out for a range of turbine inlet temperatures [1600 0 F to 3000 0 F (870 to 1650 0 C)], number of reheats, turbine mechanical efficiency, recuperator effectiveness, and system pressure losses. Gross cycle efficiency is projected to be in the range of 55 to 60%, (fusion energy to electric power), depending on parameters selected. Turbine inlet temperatures above 2000 0 F, while they do increase efficiency somewhat, are not necessarily for high cycle efficiency

Estimating spillover benefits of large R and D projects: Application of real options modelling approach to the case of thermonuclear fusion R and D programme

International Nuclear Information System (INIS)

Bednyagin, Denis; Gnansounou, Edgard

2012-01-01

This paper is focused on the analysis of spillover benefits of the ongoing R and D programme on thermonuclear fusion technology. The spillover effects are understood here as positive externalities of publicly funded R and D, demonstration and deployment (RDDD) activities that may be revealed at the companies' level in the form of newly created knowledge stock; development of innovative products/processes with broader market applications; strengthening of R and D, manufacturing and marketing capabilities; etc. An integrated compound real options model is proposed that allows to estimate the strategic net social present value of fusion RDDD programme taking into account the different types of spillover benefits along with the hidden real options value arising due to uncertainty and managerial flexibility. It was found that the value of spillover effects, modelled as “expansion option”, could represent a significant proportion of the overall socio-economic value of fusion RDDD programme (nearly 20%). This paper clearly demonstrates that, besides a high-level mission to assure sustainable energy supply, fusion RDDD programme may yield substantial net socio-economic benefits that may be at least two times higher compared to the expected RD and D costs, and hence the pursuit of even more ambitious programme is economically justified. - Highlights: ► Evaluate the strategic net social present value of fusion RDDD programme. ► Consider different types of spillover effects. ► Economic value of spillovers is estimated with a compound real options model. ► Spillover benefits could represent up to 20% of the value of fusion RDDD programme.

Fusion devices

International Nuclear Information System (INIS)

Fowler, T.K.

1977-01-01

Three types of thermonuclear fusion devices currently under development are reviewed for an electric utilities management audience. Overall design features of laser fusion, tokamak, and magnetic mirror type reactors are described and illustrated. Thrusts and trends in current research on these devices that promise to improve performance are briefly reviewed. Twenty photographs and drawings are included

Does minimal access tubular assisted spine surgery increase or decrease complications in spinal decompression or fusion?

Science.gov (United States)

Fourney, Daryl R; Dettori, Joseph R; Norvell, Daniel C; Dekutoski, Mark B

2010-04-20

Systematic review. The purpose of this review was to attempt to answer the following 2 clinical questions: (1) Does minimal access tubular assisted spine surgery (MAS) decrease the rate of complications in posterior thoracolumbar decompression and/or fusion surgery compared with traditional open techniques? (2) What strategies to reduce the risk of complications in MAS have been shown to be effective? The objective of minimal access spine surgery is to reduce damage to surrounding tissues while accomplishing the same goals as conventional surgery. Patient demand and marketing for MAS is driven by the perception of better outcomes, although the purported advantages remain unproven. Whether the risk of complications is affected by minimal access techniques is unknown. A systematic review of the English language literature was undertaken for articles published between 1990 and July 2009. Electronic databases and reference lists of key articles were searched to identify published studies that compared the rate of complications after MAS to a control group that underwent open surgery. Single-arm studies were excluded. Two independent reviewers assessed the strength of literature using GRADE criteria assessing quality, quantity, and consistency of results. Disagreements were resolved by consensus. From the 361 articles identified, 13 met a priori criteria and were included for review. All of the studies evaluated only lumbar spine surgery. The single large randomized study showed less favorable results for MAS discectomy, but no significant difference in complication rates. The quality of the other studies, particularly for fusion surgery, was low. Overall, the rates of reoperation, dural tear, cerebrospinal fluid leak, nerve injury, and infection occurred in similar proportions between MAS and open surgery. Blood loss was reduced in MAS fusion; however, the quality of those studies was very low. Operation time and hospital length of stay was variable across studies

A sensitive HIV-1 envelope induced fusion assay identifies fusion enhancement of thrombin

International Nuclear Information System (INIS)

Cheng, De-Chun; Zhong, Guo-Cai; Su, Ju-Xiang; Liu, Yan-Hong; Li, Yan; Wang, Jia-Ye; Hattori, Toshio; Ling, Hong; Zhang, Feng-Min

2010-01-01

To evaluate the interaction between HIV-1 envelope glycoprotein (Env) and target cell receptors, various cell-cell-fusion assays have been developed. In the present study, we established a novel fusion system. In this system, the expression of the sensitive reporter gene, firefly luciferase (FL) gene, in the target cells was used to evaluate cell fusion event. Simultaneously, constitutively expressed Renilla luciferase (RL) gene was used to monitor effector cell number and viability. FL gave a wider dynamic range than other known reporters and the introduction of RL made the assay accurate and reproducible. This system is especially beneficial for investigation of potential entry-influencing agents, for its power of ruling out the false inhibition or enhancement caused by the artificial cell-number variation. As a case study, we applied this fusion system to observe the effect of a serine protease, thrombin, on HIV Env-mediated cell-cell fusion and have found the fusion enhancement activity of thrombin over two R5-tropic HIV strains.

Socio-Economic research on fusion SERF 3(2001-2003) External Costs of Fusion

International Nuclear Information System (INIS)

Lechon, Y.; Saez, R.; Cabal, H.

2003-01-01

Based on SEAFP project (Raeder et al, 1995) findings a preliminary assessment of environmental external costs associated to fusion power was performed under the framework of the first phase of the SERF (Socioeconomic Research on Fusion) project (Saez et al, 1999). This study showed very low external costs of fusion power compared with other traditional and new energy generating technologies. In order to update the assessment of externalities of fusion power, SERF2 project a new plant was included and an analysis of the key variables influencing the external cost was carried out. In the new phase of the SERF project, SERF3, three new additional plant models have been introduced with the aim of assessing the possibilities of silicon carbide to be used as structural material for fusion power plants. Furthermore, comparison of fusion external costs with those of other generation technologies in the state of technology development expected for 2050 has been also performed. (Author)

Paramyxovirus F1 protein has two fusion peptides: implications for the mechanism of membrane fusion.

Science.gov (United States)

Peisajovich, S G; Samuel, O; Shai, Y

2000-03-10

Viral fusion proteins contain a highly hydrophobic segment, named the fusion peptide, which is thought to be responsible for the merging of the cellular and viral membranes. Paramyxoviruses are believed to contain a single fusion peptide at the N terminus of the F1 protein. However, here we identified an additional internal segment in the Sendai virus F1 protein (amino acids 214-226) highly homologous to the fusion peptides of HIV-1 and RSV. A synthetic peptide, which includes this region, was found to induce membrane fusion of large unilamellar vesicles, at concentrations where the known N-terminal fusion peptide is not effective. A scrambled peptide as well as several peptides from other regions of the F1 protein, which strongly bind to membranes, are not fusogenic. The functional and structural characterization of this active segment suggest that the F1 protein has an additional internal fusion peptide that could participate in the actual fusion event. The presence of homologous regions in other members of the same family suggests that the concerted action of two fusion peptides, one N-terminal and the other internal, is a general feature of paramyxoviruses. Copyright 2000 Academic Press.

Advanced fusion reactor

Energy Technology Data Exchange (ETDEWEB)

Tomita, Yukihiro [National Inst. for Fusion Science, Toki, Gifu (Japan)

2003-04-01

The main subjects on fusion research are now on D-T fueled fusion, mainly due to its high fusion reaction rate. However, many issues are still remained on the wall loading by the 14 MeV neutrons. In the case of D-D fueled fusion, the neutron wall loading is still remained, though the technology related to tritium breeding is not needed. The p-{sup 6}Li and p-{sup 11}B fueled fusions are not estimated to be the next generation candidate until the innovated plasma confinement technologies come in useful to achieve the high performance plasma parameters. The fusion reactor of D-{sup 3}He fuels has merits on the smaller neutron wall loading and tritium handling. However, there are difficulties on achieving the high temperature plasma more than 100 keV. Furthermore the high beta plasma is needed to decrease synchrotron radiation loss. In addition, the efficiency of the direct energy conversion from protons coming out from fusion reaction is one of the key parameters in keeping overall power balance. Therefore, open magnetic filed lines should surround the plasma column. In this paper, we outlined the design of the commercial base reactor (ARTEMIS) of 1 GW electric output power configured by D-{sup 3}He fueled FRC (Field Reversed Configuration). The ARTEMIS needs 64 kg of {sup 3}He per a year. On the other hand, 1 million tons of {sup 3}He is estimated to be in the moon. The {sup 3}He of about 10{sup 23} kg are to exist in gaseous planets such as Jupiter and Saturn. (Y. Tanaka)

Energy by nuclear fusion

International Nuclear Information System (INIS)

Buende, R.; Daenner, W.; Herold, H.; Raeder, J.

1976-12-01

This report reviews the state of knowledge in a number of fields of fusion research up to autumn 1976. Section 1 gives a very brief presentation of the elementary fusion reactions, the energies delivered by them and the most basic energy balances leading to Lawson-type diagrams. Section 2 outlines the reserves and cost of lithium and deuterium, gives estimates of the total energy available from DT fusion and comments on production technology, availlability and handling of the fuels. In section 3 a survey is given of the different concepts of magnetic confinement (stellarators, tokamaks, toroidal pinches, mirror machines, two-component plasmas), of confinement by walls, gas blankets and imploding liners and, finally, of the concepts of interial confinement (laser fusion, beam fusion). The reactors designed or outlined on the basis of the tokamak, high-β, mirror, and laser fusion concepts are presented in section 4, which is followed in section 5 by a discussion of the key problems of fusion power plants. The present-day knowledge of the cost structure of fusion power plants and the sensitivity of this structure with respect to the physical and technical assumptions made is analysed in section 6. Section 7 and 8 treat the aspects of safety and environment. The problems discussed include the hazard potentials of different designs (radiological, toxicological, and with respect to stored energies), release of radioactivity, possible kinds of malfunctioning, and the environmental impact of waste heat, radiation and radioactive waste (orig.) [de

Fusion research principles

CERN Document Server

Dolan, Thomas James

2013-01-01

Fusion Research, Volume I: Principles provides a general description of the methods and problems of fusion research. The book contains three main parts: Principles, Experiments, and Technology. The Principles part describes the conditions necessary for a fusion reaction, as well as the fundamentals of plasma confinement, heating, and diagnostics. The Experiments part details about forty plasma confinement schemes and experiments. The last part explores various engineering problems associated with reactor design, vacuum and magnet systems, materials, plasma purity, fueling, blankets, neutronics

Fusion Simulation Program

International Nuclear Information System (INIS)

Greenwald, Martin

2011-01-01

Many others in the fusion energy and advanced scientific computing communities participated in the development of this plan. The core planning team is grateful for their important contributions. This summary is meant as a quick overview the Fusion Simulation Program's (FSP's) purpose and intentions. There are several additional documents referenced within this one and all are supplemental or flow down from this Program Plan. The overall science goal of the DOE Office of Fusion Energy Sciences (FES) Fusion Simulation Program (FSP) is to develop predictive simulation capability for magnetically confined fusion plasmas at an unprecedented level of integration and fidelity. This will directly support and enable effective U.S. participation in International Thermonuclear Experimental Reactor (ITER) research and the overall mission of delivering practical fusion energy. The FSP will address a rich set of scientific issues together with experimental programs, producing validated integrated physics results. This is very well aligned with the mission of the ITER Organization to coordinate with its members the integrated modeling and control of fusion plasmas, including benchmarking and validation activities. (1). Initial FSP research will focus on two critical Integrated Science Application (ISA) areas: ISA1, the plasma edge; and ISA2, whole device modeling (WDM) including disruption avoidance. The first of these problems involves the narrow plasma boundary layer and its complex interactions with the plasma core and the surrounding material wall. The second requires development of a computationally tractable, but comprehensive model that describes all equilibrium and dynamic processes at a sufficient level of detail to provide useful prediction of the temporal evolution of fusion plasma experiments. The initial driver for the whole device model will be prediction and avoidance of discharge-terminating disruptions, especially at high performance, which are a critical

Barrier distribution in the heavy-ions fusion near Coulomb barrier

International Nuclear Information System (INIS)

Shilov, V.M.

1992-01-01

Experimental data on fusion cross section and average angular momenta of the compound nucleus are analyzed on the basis of the coupled-channel model for the reactions 32 S+ 100 Mo and 36 S+ 96 Mo. It is shown that it is important to take into account the transfer channels with positive value Q r for the description of the data. The intermediate coupling between excited states changes the distribution of barriers and approximates them to the ones of the Stelson phenomenological model. 22 refs.; 4 figs.; 2 tabs

Efficacy of different bone volume expanders for augmenting lumbar fusions.

Science.gov (United States)

Epstein, Nancy E

2008-01-01

A wide variety of bone volume expanders are being used in performing posterolateral lumbar noninstrumented and instrumented lumbar fusions. This article presents a review of their efficacy based on fusion rates, complications, and outcomes. Lumbar noninstrumented and instrumented fusions frequently use laminar autografts and different bone graft expanders. This review presents the utility of multiple forms/ratios of DBMs containing allografts. It also discusses the efficacy of artificial bone graft substitutes, including HA and B-TCP. Dynamic x-ray and/or CT examinations were used to document fusion in most series. Outcomes were variously assessed using Odom's criteria or different outcome questionnaires (Oswestry Questionnaire, SF-36, Dallas Pain Questionnaire, and/or Low Back Pain Rating Scale). Performing noninstrumented and instrumented lumbar posterolateral fusions resulted in comparable fusion rates in many series. Similar outcomes were also documented based on Odom's criteria or the multiple patient-based questionnaires. However, in some studies, the addition of spinal instrumentation increased the reoperation rate, operative time, blood loss, and cost. Various forms of DBMs, applied in different ratios to autografts, effectively supplemented spinal fusions in animal models and patient series. beta-Tricalcium phosphate, which is used to augment autograft fusions addressing idiopathic scoliosis or lumbar disease, also proved to be effective. Different types of bone volume expanders, including various forms of allograft-based DBMs, and artificial bone graft substitutes (HA and B-TCP) effectively promote posterolateral lumbar noninstrumented and instrumented fusions when added to autografts.

Nuclear Fusion with Polarized Nucleons & PolFusion

CERN Document Server

Engels, Ralf; Büscher, Markus; Vasilyev, Alexander

2016-01-01

This book offers a detailed examination of the latest work on the potential of polarized fuel to realize the vision of energy production by nuclear fusion. It brings together contributions from nuclear physicists and fusion physicists with the aims of fostering exchange of information between the two communities, describing the current status in the field, and examining new ideas and projects under development. It is evident that polarized fuel can offer huge improvements for the first generation of fusion reactors and open new technological possibilities for future generations, including neutron lean reactors, which could be the most popular and sustainable energy production option to avoid environmental problems. Nevertheless, many questions must be resolved before polarized fuel can be used for energy production in the different reactor types. Readers will find this book to be a stimulating source of information on the key issues. It is based on contributions from leading scientists delivered at the meetin...

Cell fusion and nuclear fusion in plants.

Science.gov (United States)

Maruyama, Daisuke; Ohtsu, Mina; Higashiyama, Tetsuya

2016-12-01

Eukaryotic cells are surrounded by a plasma membrane and have a large nucleus containing the genomic DNA, which is enclosed by a nuclear envelope consisting of the outer and inner nuclear membranes. Although these membranes maintain the identity of cells, they sometimes fuse to each other, such as to produce a zygote during sexual reproduction or to give rise to other characteristically polyploid tissues. Recent studies have demonstrated that the mechanisms of plasma membrane or nuclear membrane fusion in plants are shared to some extent with those of yeasts and animals, despite the unique features of plant cells including thick cell walls and intercellular connections. Here, we summarize the key factors in the fusion of these membranes during plant reproduction, and also focus on "non-gametic cell fusion," which was thought to be rare in plant tissue, in which each cell is separated by a cell wall. Copyright © 2016 Elsevier Ltd. All rights reserved.

Civilian applications of laser fusion

International Nuclear Information System (INIS)

Maniscalco, J.; Blink, J.; Buntzen, R.; Hovingh, J.; Meier, W.; Monsler, M.; Walker, P.

1978-01-01

The commercial aspects of laser fusion were evaluated in an attempt to relate the end products (neutrons and energy) to significant commercial applications. We have found that by far the largest markets and highest payoffs for laser fusion are associated with electric power production. Hence, much of this report evaluates the prospects of producing commercial electricity with laser fusion. To this end, we have described in detail a new and promising laser fusion concept--the liquid lithium waterfall reactor. In addition, we have taken the most attractive features from our laser fusion studies and used them to compare laser fusion to other long-range sources of energy (breeder reactors and solar energy). It is our contention that all three sources of electrical energy should be developed to the point where the final selections are primarily based on economic competitiveness. The other potential applications of laser fusion (fissile fuel production, synthetic fuel production, actinide burning, and propulsion) are also discussed, and our preliminary plan for the engineering development of laser fusion is presented

Frontiers in fusion research

CERN Document Server

Kikuchi, Mitsuru

2011-01-01

Frontiers in Fusion Research provides a systematic overview of the latest physical principles of fusion and plasma confinement. It is primarily devoted to the principle of magnetic plasma confinement, that has been systematized through 50 years of fusion research. Frontiers in Fusion Research begins with an introduction to the study of plasma, discussing the astronomical birth of hydrogen energy and the beginnings of human attempts to harness the Sun's energy for use on Earth. It moves on to chapters that cover a variety of topics such as: * charged particle motion, * plasma kinetic theory, *

Fusion energy. What Canada can do

International Nuclear Information System (INIS)

Weller, J.A.

1988-01-01

As Canada's fusion programs have grown, Canadian capabilities in fusion science and technology have grown and matured with them. The fusion capabilities described in this booklet have come from a coordinated national effort. The Government of Canada is committed to continuing its fusion energy program, and to supporting global fusion efforts. These first pages provide an overview of Canada's fusion work and its underlying basis of science and technology

Fusion-power demonstration

International Nuclear Information System (INIS)

Henning, C.D.; Logan, B.G.; Carlson, G.A.; Neef, W.S.; Moir, R.W.; Campbell, R.B.; Botwin, R.; Clarkson, I.R.; Carpenter, T.J.

1983-01-01

As a satellite to the MARS (Mirror Advanced Reactor Study) a smaller, near-term device has been scoped, called the FPD (Fusion Power Demonstration). Envisioned as the next logical step toward a power reactor, it would advance the mirror fusion program beyond MFTF-B and provide an intermediate step toward commercial fusion power. Breakeven net electric power capability would be the goal such that no net utility power would be required to sustain the operation. A phased implementation is envisioned, with a deuterium checkout first to verify the plasma systems before significant neutron activation has occurred. Major tritium-related facilities would be installed with the second phase to produce sufficient fusion power to supply the recirculating power to maintain the neutral beams, ECRH, magnets and other auxiliary equipment

Fusion power demonstration

International Nuclear Information System (INIS)

Henning, C.D.; Logan, B.G.

1983-01-01

As a satellite to the MARS (Mirror Advanced Reactor Study) a smaller, near-term device has been scoped, called the FPD (Fusion Power Demonstration). Envisioned as the next logical step toward a power reactor, it would advance the mirror fusion program beyond MFTF-B and provide an intermediate step toward commercial fusion power. Breakeven net electric power capability would be the goal such that no net utility power would be required to sustain the operation. A phased implementation is envisioned, with a deuterium checkout first to verify the plasma systems before significant neutron activation has occurred. Major tritium-related facilities would be installed with the second phase to produce sufficient fusion power to supply the recirculating power to maintain the neutral beams, ECRH, magnets and other auxiliary equipment

Materials for fusion reactors