WorldWideScience

Sample records for components domains technical

  1. Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions.

    Science.gov (United States)

    Vucetic, Slobodan; Xie, Hongbo; Iakoucheva, Lilia M; Oldfield, Christopher J; Dunker, A Keith; Obradovic, Zoran; Uversky, Vladimir N

    2007-05-01

    Biologically active proteins without stable ordered structure (i.e., intrinsically disordered proteins) are attracting increased attention. Functional repertoires of ordered and disordered proteins are very different, and the ability to differentiate whether a given function is associated with intrinsic disorder or with a well-folded protein is crucial for modern protein science. However, there is a large gap between the number of proteins experimentally confirmed to be disordered and their actual number in nature. As a result, studies of functional properties of confirmed disordered proteins, while helpful in revealing the functional diversity of protein disorder, provide only a limited view. To overcome this problem, a bioinformatics approach for comprehensive study of functional roles of protein disorder was proposed in the first paper of this series (Xie, H.; Vucetic, S.; Iakoucheva, L. M.; Oldfield, C. J.; Dunker, A. K.; Obradovic, Z.; Uversky, V. N. Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions. J. Proteome Res. 2007, 5, 1882-1898). Applying this novel approach to Swiss-Prot sequences and functional keywords, we found over 238 and 302 keywords to be strongly positively or negatively correlated, respectively, with long intrinsically disordered regions. This paper describes approximately 90 Swiss-Prot keywords attributed to the cellular components, domains, technical terms, developmental processes, and coding sequence diversities possessing strong positive and negative correlation with long disordered regions.

  2. Functional Anthology of Intrinsic Disorder. II. Cellular Components, Domains, Technical Terms, Developmental Processes and Coding Sequence Diversities Correlated with Long Disordered Regions

    Science.gov (United States)

    Vucetic, Slobodan; Xie, Hongbo; Iakoucheva, Lilia M.; Oldfield, Christopher J.; Dunker, A. Keith; Obradovic, Zoran; Uversky, Vladimir N.

    2008-01-01

    Biologically active proteins without stable ordered structure (i.e., intrinsically disordered proteins) are attracting increased attention. Functional repertoires of ordered and disordered proteins are very different, and the ability to differentiate whether a given function is associated with intrinsic disorder or with a well-folded protein is crucial for modern protein science. However, there is a large gap between the number of proteins experimentally confirmed to be disordered and their actual number in nature. As a result, studies of functional properties of confirmed disordered proteins, while helpful in revealing the functional diversity of protein disorder, provide only a limited view. To overcome this problem, a bioinformatics approach for comprehensive study of functional roles of protein disorder was proposed in the first paper of this series (Xie H., Vucetic S., Iakoucheva L.M., Oldfield C.J., Dunker A.K., Obradovic Z., Uversky V.N. (2006) Functional anthology of intrinsic disorder. I. Biological processes and functions of proteins with long disordered regions. J. Proteome Res.). Applying this novel approach to Swiss-Prot sequences and functional keywords, we found over 238 and 302 keywords to be strongly positively or negatively correlated, respectively, with long intrinsically disordered regions. This paper describes ~90 Swiss-Prot keywords attributed to the cellular components, domains, technical terms, developmental processes and coding sequence diversities possessing strong positive and negative correlation with long disordered regions. PMID:17391015

  3. NHI Component Technical Readiness Evaluation System

    International Nuclear Information System (INIS)

    Sherman, S.; Wilson, Dane F.; Pawel, Steven J.

    2007-01-01

    A decision process for evaluating the technical readiness or maturity of components (i.e., heat exchangers, chemical reactors, valves, etc.) for use by the U.S. DOE Nuclear Hydrogen Initiative is described. This system is used by the DOE NHI to assess individual components in relation to their readiness for pilot-scale and larger-scale deployment and to drive the research and development work needed to attain technical maturity. A description of the evaluation system is provided, and examples are given to illustrate how it is used to assist in component R and D decisions.

  4. Technical considerations relative to removal of sodium from LMFBR components

    Energy Technology Data Exchange (ETDEWEB)

    McDonald, J S; Asquith, J G

    1975-07-01

    Reviewed in this paper are technical considerations which are of importance in choosing between an alcohol process and a moist nitrogen process for the removal of sodium from LMFBR components. Results observed in laboratory tests and in the cleaning of large scale components (e.g. a 28 MWt Modular Steam Generator Test Unit) are presented and discussed. (author)

  5. Cross Domain Deterrence: Livermore Technical Report, 2014-2016

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Peter D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bahney, Ben [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Matarazzo, Celeste [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Markey, Michael [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pearl, Jonathan [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-08-03

    Lawrence Livermore National Laboratory (LLNL) is an original collaborator on the project titled “Deterring Complex Threats: The Effects of Asymmetry, Interdependence, and Multi-polarity on International Strategy,” (CDD Project) led by the UC Institute on Global Conflict and Cooperation at UCSD under PIs Jon Lindsay and Erik Gartzke , and funded through the DoD Minerva Research Initiative. In addition to participating in workshops and facilitating interaction among UC social scientists, LLNL is leading the computational modeling effort and assisting with empirical case studies to probe the viability of analytic, modeling and data analysis concepts. This report summarizes LLNL work on the CDD Project to date, primarily in Project Years 1-2, corresponding to Federal fiscal year 2015. LLNL brings two unique domains of expertise to bear on this Project: (1) access to scientific expertise on the technical dimensions of emerging threat technology, and (2) high performance computing (HPC) expertise, required for analyzing the complexity of bargaining interactions in the envisioned threat models. In addition, we have a small group of researchers trained as social scientists who are intimately familiar with the International Relations research. We find that pairing simulation scientists, who are typically trained in computer science, with domain experts, social scientists in this case, is the most effective route to developing powerful new simulation tools capable of representing domain concepts accurately and answering challenging questions in the field.

  6. Modular Domain-Specific Language Components in Scala

    DEFF Research Database (Denmark)

    Hofer, Christian; Ostermann, Klaus

    2010-01-01

    Programs in domain-­specific embedded languages (DSELs) can be represented in the host language in different ways, for instance implicitly as libraries, or explicitly in the form of abstract syntax trees. Each of these representations has its own strengths and weaknesses. The implicit approach ha...... or transformation. We propose a new design for implementing DSELs in Scala which makes it easy to use different program representations at the same time. It enables the DSL implementor to define modular language components and to compose transformations and interpretations for them....

  7. Hybrid time/frequency domain modeling of nonlinear components

    DEFF Research Database (Denmark)

    Wiechowski, Wojciech Tomasz; Lykkegaard, Jan; Bak, Claus Leth

    2007-01-01

    This paper presents a novel, three-phase hybrid time/frequency methodology for modelling of nonlinear components. The algorithm has been implemented in the DIgSILENT PowerFactory software using the DIgSILENT Programming Language (DPL), as a part of the work described in [1]. Modified HVDC benchmark...

  8. Cognitive components of regularity processing in the auditory domain.

    Directory of Open Access Journals (Sweden)

    Stefan Koelsch

    Full Text Available BACKGROUND: Music-syntactic irregularities often co-occur with the processing of physical irregularities. In this study we constructed chord-sequences such that perceived differences in the cognitive processing between regular and irregular chords could not be due to the sensory processing of acoustic factors like pitch repetition or pitch commonality (the major component of 'sensory dissonance'. METHODOLOGY/PRINCIPAL FINDINGS: Two groups of subjects (musicians and nonmusicians were investigated with electroencephalography (EEG. Irregular chords elicited an early right anterior negativity (ERAN in the event-related brain potentials (ERPs. The ERAN had a latency of around 180 ms after the onset of the music-syntactically irregular chords, and had maximum amplitude values over right anterior electrode sites. CONCLUSIONS/SIGNIFICANCE: Because irregular chords were hardly detectable based on acoustical factors (such as pitch repetition and sensory dissonance, this ERAN effect reflects for the most part cognitive (not sensory components of regularity-based, music-syntactic processing. Our study represents a methodological advance compared to previous ERP-studies investigating the neural processing of music-syntactically irregular chords.

  9. Technical efficiency of Shiraz school of medicine in research and education domains: a data envelopment analysis.

    Science.gov (United States)

    Delavari, Somayeh; Rezaee, Rita; Hatam, Nahid; Delavari, Sajad

    2016-01-01

    Efficiency evaluation of universities and faculties is one of the tools that help managers to identify the departments' strengths and weakness. The main objective of the present research was to measure and compare the technical efficiency of Shiraz school of medicine departments using Data Envelopment Analysis (DEA) technique. This cross-sectional and retrospective study was performed on clinical and non-clinical departments in research and education domains over the period of 2006 to 2011. Different inputs and outputs were considered for research and educational domain separately. Efficiency was measured based on the observed optimal performance. Findings showed that pathology and anatomy departments achieved the score of 100 in technical efficiency in education during 2006 to 2011. During this period, parasitology, psychiatric and pediatrics department's achieved the score of 100 for technical efficiency in research domain. The lowest mean of relative educational efficiency belonged to orthopedic department; as to relative research efficiency, the lowest mean was shown in orthopedics and genetics departments. The mean technical efficiency of non-medical departments in education and research domain was 91.93 and 76.08, respectively, while the mean technical efficiency of the clinical department in educational and research fields was 91.02 and 82.23, respectively. Using multiple input and output in DEA technique provided a comprehensive evaluation of efficiency in Shiraz school of medicine departments. The DEA could successfully estimate the technical efficiency of the departments in research and educational fields. Moreover, the deficiency in each department was found; this could help them to plan for improvement.

  10. ASME code and ratcheting in piping components. Final technical report

    International Nuclear Information System (INIS)

    Hassan, T.; Matzen, V.C.

    1999-01-01

    The main objective of this research is to develop an analysis program which can accurately simulate ratcheting in piping components subjected to seismic or other cyclic loads. Ratcheting is defined as the accumulation of deformation in structures and materials with cycles. This phenomenon has been demonstrated to cause failure to piping components (known as ratcheting-fatigue failure) and is yet to be understood clearly. The design and analysis methods in the ASME Boiler and Pressure Vessel Code for ratcheting of piping components are not well accepted by the practicing engineering community. This research project attempts to understand the ratcheting-fatigue failure mechanisms and improve analysis methods for ratcheting predictions. In the first step a state-of-the-art testing facility is developed for quasi-static cyclic and seismic testing of straight and elbow piping components. A systematic testing program to study ratcheting is developed. Some tests have already been performed and the rest will be completed by summer'99. Significant progress has been made in the area of constitutive modeling. A number of sophisticated constitutive models have been evaluated in terms of their simulations for a broad class of ratcheting responses. From the knowledge gained from this evaluation study two improved models are developed. These models are demonstrated to have promise in simulating ratcheting responses in piping components. Hence, implementation of these improved models in widely used finite element programs, ANSYS and/or ABAQUS, is in progress. Upon achieving improved finite element programs for simulation of ratcheting, the ASME Code provisions for ratcheting of piping components will be reviewed and more rational methods will be suggested. Also, simplified analysis methods will be developed for operability studies of piping components and systems. Some of the future works will be performed under the auspices of the Center for Nuclear Power Plant Structures

  11. The Intercultural Component in Textbooks for Teaching a Service Technical Writing Course

    Science.gov (United States)

    Matveeva, Natalia

    2007-01-01

    This research article investigates new developments in the representation of the intercultural component in textbooks for a service technical writing course. Through textual analysis, using quantitative and qualitative techniques, I report discourse analysis of 15 technical writing textbooks published during 1993-2006. The theoretical and…

  12. Repair welding of fusion reactor components. Final technical report

    International Nuclear Information System (INIS)

    Chin, B.A.; Wang, C.A.

    1997-01-01

    The exposure of metallic materials, such as structural components of the first wall and blanket of a fusion reactor, to neutron irradiation will induce changes in both the material composition and microstructure. Along with these changes can come a corresponding deterioration in mechanical properties resulting in premature failure. It is, therefore, essential to expect that the repair and replacement of the degraded components will be necessary. Such repairs may require the joining of irradiated materials through the use of fusion welding processes. The present ITER (International Thermonuclear Experimental Reactor) conceptual design is anticipated to have about 5 km of longitudinal welds and ten thousand pipe butt welds in the blanket structure. A recent study by Buende et al. predict that a failure is most likely to occur in a weld. The study is based on data from other large structures, particularly nuclear reactors. The data used also appear to be consistent with the operating experience of the Fast Flux Test Facility (FFTF). This reactor has a fuel pin area comparable with the area of the ITER first wall and has experienced one unanticipated fuel pin failure after two years of operation. The repair of irradiated structures using fusion welding will be difficult due to the entrapped helium. Due to its extremely low solubility in metals, helium will diffuse and agglomerate to form helium bubbles after being trapped at point defects, dislocations, and grain boundaries. Welding of neutron-irradiated type 304 stainless steels has been reported with varying degree of heat-affected zone cracking (HAZ). The objectives of this study were to determine the threshold helium concentrations required to cause HAZ cracking and to investigate techniques that might be used to eliminate the HAZ cracking in welding of helium-containing materials

  13. Stability equation and two-component Eigenmode for domain walls in scalar potential model

    International Nuclear Information System (INIS)

    Dias, G.S.; Graca, E.L.; Rodrigues, R. de Lima

    2002-08-01

    Supersymmetric quantum mechanics involving a two-component representation and two-component eigenfunctions is applied to obtain the stability equation associated to a potential model formulated in terms of two coupled real scalar fields. We investigate the question of stability by introducing an operator technique for the Bogomol'nyi-Prasad-Sommerfield (BPS) and non-BPS states on two domain walls in a scalar potential model with minimal N 1-supersymmetry. (author)

  14. MITT writer and MITT writer advanced development: Developing authoring and training systems for complex technical domains

    Science.gov (United States)

    Wiederholt, Bradley J.; Browning, Elica J.; Norton, Jeffrey E.; Johnson, William B.

    1991-01-01

    MITT Writer is a software system for developing computer based training for complex technical domains. A training system produced by MITT Writer allows a student to learn and practice troubleshooting and diagnostic skills. The MITT (Microcomputer Intelligence for Technical Training) architecture is a reasonable approach to simulation based diagnostic training. MITT delivers training on available computing equipment, delivers challenging training and simulation scenarios, and has economical development and maintenance costs. A 15 month effort was undertaken in which the MITT Writer system was developed. A workshop was also conducted to train instructors in how to use MITT Writer. Earlier versions were used to develop an Intelligent Tutoring System for troubleshooting the Minuteman Missile Message Processing System.

  15. Research on Evaluation Methodology for High Temperature Components and Technical Issues

    International Nuclear Information System (INIS)

    Kim, Y.J.; Han, S.B.

    2007-03-01

    The research on evaluation methodology for high temperature components and technical issues includes the comparison of evaluation technology of Very High Temperature Reactors(VHTRs) with that of present commercial reactors, the review of Hot Gas Duct(HGD) insulation designs, the analysis of the codes related to VHTR component construction and the analysis of technical issues on application of present codes to HGD construction. Codes to assure the integrity of the VHTR components are not fully prepared yet in any country. To understand the evaluation technology of the VHTR-related codes, key requirements of ASME B and PV Code Section III, Subsection NB and NH were compared. Six kinds of HGD designs were reviewed and compared. A reference which analyzed seven kinds of present component codes were reviewed and the limitations of them were summarized. Especially it was found that the selection of materials is limited, material property data are not enough, and design analysis methodology is not fully specified

  16. Simulated lumbar minimally invasive surgery educational model with didactic and technical components.

    Science.gov (United States)

    Chitale, Rohan; Ghobrial, George M; Lobel, Darlene; Harrop, James

    2013-10-01

    The learning and development of technical skills are paramount for neurosurgical trainees. External influences and a need for maximizing efficiency and proficiency have encouraged advancements in simulator-based learning models. To confirm the importance of establishing an educational curriculum for teaching minimally invasive techniques of pedicle screw placement using a computer-enhanced physical model of percutaneous pedicle screw placement with simultaneous didactic and technical components. A 2-hour educational curriculum was created to educate neurosurgical residents on anatomy, pathophysiology, and technical aspects associated with image-guided pedicle screw placement. Predidactic and postdidactic practical and written scores were analyzed and compared. Scores were calculated for each participant on the basis of the optimal pedicle screw starting point and trajectory for both fluoroscopy and computed tomographic navigation. Eight trainees participated in this module. Average mean scores on the written didactic test improved from 78% to 100%. The technical component scores for fluoroscopic guidance improved from 58.8 to 52.9. Technical score for computed tomography-navigated guidance also improved from 28.3 to 26.6. Didactic and technical quantitative scores with a simulator-based educational curriculum improved objectively measured resident performance. A minimally invasive spine simulation model and curriculum may serve a valuable function in the education of neurosurgical residents and outcomes for patients.

  17. Constructing a Cross-Domain Resource Inventory: Key Components and Results of the EarthCube CINERGI Project.

    Science.gov (United States)

    Zaslavsky, I.; Richard, S. M.; Malik, T.; Hsu, L.; Gupta, A.; Grethe, J. S.; Valentine, D. W., Jr.; Lehnert, K. A.; Bermudez, L. E.; Ozyurt, I. B.; Whitenack, T.; Schachne, A.; Giliarini, A.

    2015-12-01

    While many geoscience-related repositories and data discovery portals exist, finding information about available resources remains a pervasive problem, especially when searching across multiple domains and catalogs. Inconsistent and incomplete metadata descriptions, disparate access protocols and semantic differences across domains, and troves of unstructured or poorly structured information which is hard to discover and use are major hindrances toward discovery, while metadata compilation and curation remain manual and time-consuming. We report on methodology, main results and lessons learned from an ongoing effort to develop a geoscience-wide catalog of information resources, with consistent metadata descriptions, traceable provenance, and automated metadata enhancement. Developing such a catalog is the central goal of CINERGI (Community Inventory of EarthCube Resources for Geoscience Interoperability), an EarthCube building block project (earthcube.org/group/cinergi). The key novel technical contributions of the projects include: a) development of a metadata enhancement pipeline and a set of document enhancers to automatically improve various aspects of metadata descriptions, including keyword assignment and definition of spatial extents; b) Community Resource Viewers: online applications for crowdsourcing community resource registry development, curation and search, and channeling metadata to the unified CINERGI inventory, c) metadata provenance, validation and annotation services, d) user interfaces for advanced resource discovery; and e) geoscience-wide ontology and machine learning to support automated semantic tagging and faceted search across domains. We demonstrate these CINERGI components in three types of user scenarios: (1) improving existing metadata descriptions maintained by government and academic data facilities, (2) supporting work of several EarthCube Research Coordination Network projects in assembling information resources for their domains

  18. Technical meeting on materials for in-vessel components of ITER

    International Nuclear Information System (INIS)

    Kalinin, G.; Barabash, V.

    2000-01-01

    The Technical meeting on materials for in-vessel components of ITER was held at the ITER Joint Work Site in Garching from 31 January to 4 February. The main objectives of the meetings were: 1. to summarize the requirements, 2. to review new data, 3. to discuss in detail the R and D program and to discuss the material assessment report

  19. The Use of Workforce Assessment as a Component of Career and Technical Education Program Evaluation

    Science.gov (United States)

    Bartlett, Kenneth R.; Schleif, Nicole L.; Bowen, Mauvalyn M.

    2011-01-01

    This research project examined the extent to which Career and Technical Education (CTE)-related programs use workforce needs assessment as a component of their evaluation activities. An employer perspective was used to develop a conceptual framework drawing on strategic human resource management theory. The extent and methods utilized for…

  20. Modern technical diagnostic system for the main components of powerful turbine generator

    International Nuclear Information System (INIS)

    Ezovit, G.P.; Uglyarenko, V.P.; Burlaka, S.I.; Goroz, N.I.; Orinin, S.E.; Komaritsa, V.N.; Zav'yalov, D.N.; Mazurenko, O.A.

    2011-01-01

    The modern diagnostic system to monitor the technical state of a powerful turbine generator is considered. This system permits the detection of defects in its main components and cooling system at the early stage of their development, prevention of damage and, as a consequence, emergency shutdown of nuclear power units

  1. The Twofold Multidimensionality of Academic Self-Concept: Domain Specificity and Separation between Competence and Affect Components

    Science.gov (United States)

    Arens, A. Katrin; Yeung, Alexander Seeshing; Craven, Rhonda G.; Hasselhorn, Marcus

    2011-01-01

    Academic self-concept is consistently proven to be multidimensional rather than unidimensional as it is domain specific in nature. However, each specific self-concept domain may be further separated into competence and affect components. This study examines the twofold multidimensionality of academic self-concept (i.e., its domain specificity and…

  2. Final Technical Report - Integrated Hydrogeophysical and Hydrogeologic Driven Parameter Upscaling for Dual-Domain Transport Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Shafer, John M

    2012-11-05

    The three major components of this research were: 1. Application of minimally invasive, cost effective hydrogeophysical techniques (surface and borehole), to generate fine scale (~1m or less) 3D estimates of subsurface heterogeneity. Heterogeneity is defined as spatial variability in hydraulic conductivity and/or hydrolithologic zones. 2. Integration of the fine scale characterization of hydrogeologic parameters with the hydrogeologic facies to upscale the finer scale assessment of heterogeneity to field scale. 3. Determination of the relationship between dual-domain parameters and practical characterization data.

  3. Experience with the source evaluation board method of procuring technical components for the Fermilab Main Injector

    International Nuclear Information System (INIS)

    Harding, D.J.; Collins, J.P.; Kobliska, G.R.; Chester, N.S.; Pewitt, E.G.; Fowler, W.B.

    1993-01-01

    Fermilab has adopted the Source Evaluation Board (SEB) method for procuring certain major technical components of the Fermilab Main Injector. The SEB procedure is designed to ensure the efficient and effective expenditure of Government funds at the same time that it optimizes the opportunity for attainment of project objectives. A qualitative trade-off is allowed between price and technical factors. The process involves a large amount of work and is only justified for a very limited number of procurements. Fermilab has gained experience with the SEB process in awarding subcontracts for major subassemblies of the Fermilab Main Injector dipoles

  4. Simulated spinal cerebrospinal fluid leak repair: an educational model with didactic and technical components.

    Science.gov (United States)

    Ghobrial, George M; Anderson, Paul A; Chitale, Rohan; Campbell, Peter G; Lobel, Darlene A; Harrop, James

    2013-10-01

    In the era of surgical resident work hour restrictions, the traditional apprenticeship model may provide fewer hours for neurosurgical residents to hone technical skills. Spinal dura mater closure or repair is 1 skill that is infrequently encountered, and persistent cerebrospinal fluid leaks are a potential morbidity. To establish an educational curriculum to train residents in spinal dura mater closure with a novel durotomy repair model. The Congress of Neurological Surgeons has developed a simulation-based model for durotomy closure with the ongoing efforts of their simulation educational committee. The core curriculum consists of didactic training materials and a technical simulation model of dural repair for the lumbar spine. Didactic pretest scores ranged from 4/11 (36%) to 10/11 (91%). Posttest scores ranged from 8/11 (73%) to 11/11 (100%). Overall, didactic improvements were demonstrated by all participants, with a mean improvement between pre- and posttest scores of 1.17 (18.5%; P = .02). The technical component consisted of 11 durotomy closures by 6 participants, where 4 participants performed multiple durotomies. Mean time to closure of the durotomy ranged from 490 to 546 seconds in the first and second closures, respectively (P = .66), whereby the median leak rate improved from 14 to 7 (P = .34). There were also demonstrative technical improvements by all. Simulated spinal dura mater repair appears to be a potentially valuable tool in the education of neurosurgery residents. The combination of a didactic and technical assessment appears to be synergistic in terms of educational development.

  5. Structural studies of the activation of the two component receiver domain NTRC by multidimensional heteronuclear NMR

    Energy Technology Data Exchange (ETDEWEB)

    Nohaile, Michael James [Univ. of California, Berkeley, CA (United States). Dept. of Chemistry

    1996-05-01

    Multidimensional heteronuclear NMR spectroscopy was used to investigate the N-terminal domain of the transcriptional enhancer NTRC (NiTrogen Regulatory protein C). This domain belongs to the family of receiver domains of two-component regulatory systems involved in signal transduction. Phosphorylation of NTRC at D54 leads to an activated form of the molecule which stimulates transcription of genes involved in nitrogen regulation. Three and four dimensional NMR techniques were used to determine an intermediate resolution structure of the unphosphorylated, inactive form of the N-terminal domain of NTRC. The structure is comprised of five α-helices and a five-stranded β-sheet in a (β/α)5 topology. Analysis of the backbone dynamics of NTRC indicate that helix 4 and strand 5 are significantly more flexible than the rest of the secondary structure of the protein and that the loops making up the active site are flexible. The short lifetime of phospho-NTRC hampers the study of this form. However, conditions for determining the resonance assignments and, possibly, the three dimensional structure of phosphorylated NTRC have been obtained. Tentative assignments of the phosphorylated form indicate that the majority of the changes that NTRC experiences upon phosphorylation occur in helix 3, strand 4, helix 4, strand 5, and the loop between strand 5 and helix 5 (the 3445 face of NTRC) as well as near the site of phosphorylation. In order to examine a stable, activated form of the protein, constitutively active mutants of NTRC were investigated.

  6. Co-evolution of intelligent socio-technical systems modelling and applications in large scale emergency and transport domains

    CERN Document Server

    2013-01-01

    As the interconnectivity between humans through technical devices is becoming ubiquitous, the next step is already in the making: ambient intelligence, i.e. smart (technical) environments, which will eventually play the same active role in communication as the human players, leading to a co-evolution in all domains where real-time communication is essential. This topical volume, based on the findings of the Socionical European research project, gives equal attention to two highly relevant domains of applications: transport, specifically traffic, dynamics from the viewpoint of a socio-technical interaction and evacuation scenarios for large-scale emergency situations. Care was taken to investigate as much as possible the limits of scalability and to combine the modeling using complex systems science approaches with relevant data analysis.

  7. Technical Note: Introduction of variance component analysis to setup error analysis in radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Matsuo, Yukinori, E-mail: ymatsuo@kuhp.kyoto-u.ac.jp; Nakamura, Mitsuhiro; Mizowaki, Takashi; Hiraoka, Masahiro [Department of Radiation Oncology and Image-applied Therapy, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo, Kyoto 606-8507 (Japan)

    2016-09-15

    Purpose: The purpose of this technical note is to introduce variance component analysis to the estimation of systematic and random components in setup error of radiotherapy. Methods: Balanced data according to the one-factor random effect model were assumed. Results: Analysis-of-variance (ANOVA)-based computation was applied to estimate the values and their confidence intervals (CIs) for systematic and random errors and the population mean of setup errors. The conventional method overestimates systematic error, especially in hypofractionated settings. The CI for systematic error becomes much wider than that for random error. The ANOVA-based estimation can be extended to a multifactor model considering multiple causes of setup errors (e.g., interpatient, interfraction, and intrafraction). Conclusions: Variance component analysis may lead to novel applications to setup error analysis in radiotherapy.

  8. Technical Note: Introduction of variance component analysis to setup error analysis in radiotherapy

    International Nuclear Information System (INIS)

    Matsuo, Yukinori; Nakamura, Mitsuhiro; Mizowaki, Takashi; Hiraoka, Masahiro

    2016-01-01

    Purpose: The purpose of this technical note is to introduce variance component analysis to the estimation of systematic and random components in setup error of radiotherapy. Methods: Balanced data according to the one-factor random effect model were assumed. Results: Analysis-of-variance (ANOVA)-based computation was applied to estimate the values and their confidence intervals (CIs) for systematic and random errors and the population mean of setup errors. The conventional method overestimates systematic error, especially in hypofractionated settings. The CI for systematic error becomes much wider than that for random error. The ANOVA-based estimation can be extended to a multifactor model considering multiple causes of setup errors (e.g., interpatient, interfraction, and intrafraction). Conclusions: Variance component analysis may lead to novel applications to setup error analysis in radiotherapy.

  9. Technical Needs for Prototypic Prognostic Technique Demonstration for Advanced Small Modular Reactor Passive Components

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, Ryan M.; Coble, Jamie B.; Hirt, Evelyn H.; Ramuhalli, Pradeep; Mitchell, Mark R.; Wootan, David W.; Berglin, Eric J.; Bond, Leonard J.; Henager, Charles H.

    2013-05-17

    This report identifies a number of requirements for prognostics health management of passive systems in AdvSMRs, documents technical gaps in establishing a prototypical prognostic methodology for this purpose, and describes a preliminary research plan for addressing these technical gaps. AdvSMRs span multiple concepts; therefore a technology- and design-neutral approach is taken, with the focus being on characteristics that are likely to be common to all or several AdvSMR concepts. An evaluation of available literature is used to identify proposed concepts for AdvSMRs along with likely operational characteristics. Available operating experience of advanced reactors is used in identifying passive components that may be subject to degradation, materials likely to be used for these components, and potential modes of degradation of these components. This information helps in assessing measurement needs for PHM systems, as well as defining functional requirements of PHM systems. An assessment of current state-of-the-art approaches to measurements, sensors and instrumentation, diagnostics and prognostics is also documented. This state-of-the-art evaluation, combined with the requirements, may be used to identify technical gaps and research needs in the development, evaluation, and deployment of PHM systems for AdvSMRs. A preliminary research plan to address high-priority research needs for the deployment of PHM systems to AdvSMRs is described, with the objective being the demonstration of prototypic prognostics technology for passive components in AdvSMRs. Greater efficiency in achieving this objective can be gained through judicious selection of materials and degradation modes that are relevant to proposed AdvSMR concepts, and for which significant knowledge already exists. These selections were made based on multiple constraints including the analysis performed in this document, ready access to laboratory-scale facilities for materials testing and measurement, and

  10. The Effect of Domain and Technical Expertise on the Training Outcomes for Case Management Systems in High Domain Expertise Fields

    Science.gov (United States)

    Epstein, Steven L.

    2017-01-01

    The successful implementation of an enterprise system requires training and end users in the new systems and procedures. There has been no research reporting a relationship between Domain Expertise (DE) and the successful implementation of an enterprise system. This study sought to begin filling this knowledge gap by exploring the relationship…

  11. Human alpha2-macroglobulin is composed of multiple domains, as predicted by homology with complement component C3.

    Science.gov (United States)

    Doan, Ninh; Gettins, Peter G W

    2007-10-01

    Human alpha2M (alpha2-macroglobulin) and the complement components C3 and C4 are thiol ester-containing proteins that evolved from the same ancestral gene. The recent structure determination of human C3 has allowed a detailed prediction of the location of domains within human alpha2M to be made. We describe here the expression and characterization of three alpha(2)M domains predicted to be involved in the stabilization of the thiol ester in native alpha2M and in its activation upon bait region proteolysis. The three newly expressed domains are MG2 (macroglobulin domain 2), TED (thiol ester-containing domain) and CUB (complement protein subcomponents C1r/C1s, urchin embryonic growth factor and bone morphogenetic protein 1) domain. Together with the previously characterized RBD (receptor-binding domain), they represent approx. 42% of the alpha2M polypeptide. Their expression as folded domains strongly supports the predicted domain organization of alpha2M. An X-ray crystal structure of MG2 shows it to have a fibronectin type-3 fold analogous to MG1-MG8 of C3. TED is, as predicted, an alpha-helical domain. CUB is a spliced domain composed of two stretches of polypeptide that flank TED in the primary structure. In intact C3 TED interacts with RBD, where it is in direct contact with the thiol ester, and with MG2 and CUB on opposite, flanking sides. In contrast, these alpha2M domains, as isolated species, show negligible interaction with one another, suggesting that the native conformation of alpha2M, and the consequent thiol ester-stabilizing domain-domain interactions, result from additional restraints imposed by the physical linkage of these domains or by additional domains in the protein.

  12. NEET-AMM Final Technical Report on Laser Direct Manufacturing (LDM) for Nuclear Power Components

    International Nuclear Information System (INIS)

    Anderson, Scott; Baca, Georgina; O'Connor, Michael

    2015-01-01

    Final technical report summarizes the program progress and technical accomplishments of the Laser Direct Manufacturing (LDM) for Nuclear Power Components project. A series of experiments varying build process parameters (scan speed and laser power) were conducted at the outset to establish the optimal build conditions for each of the alloys. Fabrication was completed in collaboration with Quad City Manufacturing Laboratory (QCML). The density of all sample specimens was measured and compared to literature values. Optimal build process conditions giving fabricated part densities close to literature values were chosen for making mechanical test coupons. Test coupons whose principal axis is on the x-y plane (perpendicular to build direction) and on the z plane (parallel to build direction) were built and tested as part of the experimental build matrix to understand the impact of the anisotropic nature of the process.. Investigations are described 316L SS, Inconel 600, 718 and 800 and oxide dispersion strengthed 316L SS (Yttria) alloys.

  13. NEET-AMM Final Technical Report on Laser Direct Manufacturing (LDM) for Nuclear Power Components

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Scott [Lockheed Martin Corporation, Denver, CO (United States). Space Systems Company; Baca, Georgina [Lockheed Martin Corporation, Denver, CO (United States). Space Systems Company; O' Connor, Michael [Lockheed Martin Corporation, Denver, CO (United States). Space Systems Company

    2015-12-31

    Final technical report summarizes the program progress and technical accomplishments of the Laser Direct Manufacturing (LDM) for Nuclear Power Components project. A series of experiments varying build process parameters (scan speed and laser power) were conducted at the outset to establish the optimal build conditions for each of the alloys. Fabrication was completed in collaboration with Quad City Manufacturing Laboratory (QCML). The density of all sample specimens was measured and compared to literature values. Optimal build process conditions giving fabricated part densities close to literature values were chosen for making mechanical test coupons. Test coupons whose principal axis is on the x-y plane (perpendicular to build direction) and on the z plane (parallel to build direction) were built and tested as part of the experimental build matrix to understand the impact of the anisotropic nature of the process.. Investigations are described 316L SS, Inconel 600, 718 and 800 and oxide dispersion strengthed 316L SS (Yttria) alloys.

  14. Co-existence of Gel and Fluid Lipid Domains in Single-component Phospholipid Membranes

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, Clare L [McMaster University; Barrett, M [McMaster University; Toppozini, L [McMaster University; Yamani, Zahra [Canadian Neutron Beam Centre, National Research Council, Chalk River Laboratorie; Kucerka, Norbert [Canadian Neutron Beam Centre and Comelius University (Slovakia); Katsaras, John [ORNL; Fragneto, Giovanna [Institut Laue-Langevin (ILL); Rheinstadter, Maikel C [McMaster University

    2012-01-01

    Lateral nanostructures in membranes, so-called rafts, are believed to strongly influence membrane properties and functions. The experimental observation of rafts has proven difficult as they are thought to be dynamic structures that likely fluctuate on nano- to microsecond time scales. Using neutron diffraction we present direct experimental evidence for the co-existence of gel and fluid lipid domains in a single-component phospholipid membrane made of DPPC as it undergoes its main phase transition. The coherence length of the neutron beam sets a lower limit for the size of structures that can be observed. Neutron coherence lengths between 30 and 242A used in this study were obtained by varying the incident neutron energy and the resolution of the neutron spectrometer. We observe Bragg peaks corresponding to co-existing nanometer sized structures, both in out-of-plane and in-plane scans, by tuning the neutron coherence length. During the main phase transition, instead of a continuous transition that shows a pseudo-critical behavior, we observe the co-existence of gel and fluid domains.

  15. Human α2-macroglobulin is composed of multiple domains, as predicted by homology with complement component C3

    Science.gov (United States)

    Doan, Ninh; Gettins, Peter G. W.

    2007-01-01

    Human α2M (α2-macroglobulin) and the complement components C3 and C4 are thiol ester-containing proteins that evolved from the same ancestral gene. The recent structure determination of human C3 has allowed a detailed prediction of the location of domains within human α2M to be made. We describe here the expression and characterization of three α2M domains predicted to be involved in the stabilization of the thiol ester in native α2M and in its activation upon bait region proteolysis. The three newly expressed domains are MG2 (macroglobulin domain 2), TED (thiol ester-containing domain) and CUB (complement protein subcomponents C1r/C1s, urchin embryonic growth factor and bone morphogenetic protein 1) domain. Together with the previously characterized RBD (receptor-binding domain), they represent approx. 42% of the α2M polypeptide. Their expression as folded domains strongly supports the predicted domain organization of α2M. An X-ray crystal structure of MG2 shows it to have a fibronectin type-3 fold analogous to MG1–MG8 of C3. TED is, as predicted, an α-helical domain. CUB is a spliced domain composed of two stretches of polypeptide that flank TED in the primary structure. In intact C3 TED interacts with RBD, where it is in direct contact with the thiol ester, and with MG2 and CUB on opposite, flanking sides. In contrast, these α2M domains, as isolated species, show negligible interaction with one another, suggesting that the native conformation of α2M, and the consequent thiol ester-stabilizing domain–domain interactions, result from additional restraints imposed by the physical linkage of these domains or by additional domains in the protein. PMID:17608619

  16. The Components of Abstracts: the Logical Structure of Abstractsin the Area of Technical Sciences

    Directory of Open Access Journals (Sweden)

    Nina Jamar

    2014-04-01

    Full Text Available ABSTRACTPurpose: The main purpose of this research was to find out what kind of structure would be the most appropriate for abstracts in the area of technical sciences, and on the basis of these findings develop guidelines for their writing.Methodology/approach: First, the components of abstracts published in journals were analyzed. Then the prototypes and recommended improved abstracts were presented. Third, the satisfaction of the readers with the different forms of abstracts was examined. According to the results of these three parts of the research, the guidelines for writing abstracts in the area of technical sciences were developed.Results: The results showed that it is possible to determine the optimum structure for abstracts from the area of technical sciences. This structure should follow the known IMRD format or BMRC structure according to the coding scheme.Research limitations: The presented research included in the analysis only abstracts from several areas that represent technical studies. In order to develop the guidelines for writing abstracts more broadly, the research should be extended with at least one more area from the natural sciences and two areas from social sciences and humanities.Original/practical implications: It is important to emphasize that even if the guidelines for writing abstracts by the individual journal exist, authors do not always take them into account. Therefore, it is important that the abstracts that are actually published in journals were analysed. It is also important that with the development of guidelines for writing abstracts the opinion of researchers was also taken into account.

  17. Three technical issues in fatigue damage assessment of nuclear power plant components

    International Nuclear Information System (INIS)

    Ware, A.G.; Shah, V.N.

    1991-01-01

    This paper addresses three technical issues that affect the fatigue damage assessment of nuclear power plant components: the effect of the environment on the fatigue life, the importance of the loading sequence in calculating the fatigue crack-initiation damage, and the adequacy of current inservice inspection requirements and methods to characterize fatigue cracks. The environmental parameters that affect the fatigue life of carbon and low alloy steel components are the sulphur content in the steel, the temperature, the amount of dissolved oxygen in the coolant, and the presence of oxidizing agents such as copper oxide. The occurrence of large-amplitude stress cycles early in a component's life followed by low-amplitude stress cycles may cause crack initiation at a cumulative usage factor less than 1.0. The current inservice inspection requirements include volumetric inspections of welds but not of some susceptible sites in the base metal. In addition, the conventional ultrasonic testing techniques need to be improved for reliable detection and accurate sizing of fatigue cracks. 28 refs., 4 figs., 1 tab

  18. Domain Walls and Textured Vortices in a Two-Component Ginzburg-Landau Model

    DEFF Research Database (Denmark)

    Madsen, Søren Peder; Gaididei, Yu. B.; Christiansen, Peter Leth

    2005-01-01

    coupling between the two order parameters a ''textured vortex'' is found by analytical and numerical solution of the Ginzburg-Landau equations. With a Josephson type coupling between the two order parameters we find the system to split up in two domains separated by a domain wall, where the order parameter...... is depressed to zero....

  19. Frequency Domain Computer Programs for Prediction and Analysis of Rail Vehicle Dynamics : Volume 1. Technical Report

    Science.gov (United States)

    1975-12-01

    Frequency domain computer programs developed or acquired by TSC for the analysis of rail vehicle dynamics are described in two volumes. Volume I defines the general analytical capabilities required for computer programs applicable to single rail vehi...

  20. Technical program to study the benefits of nonlinear analysis methods in LWR component designs. Technical report TR-3723-1

    International Nuclear Information System (INIS)

    Raju, P.P.

    1980-05-01

    This report summarizes the results of the study program to assess the benefits of nonlinear analysis methods in Light Water Reactor (LWR) component designs. The current study reveals that despite its increased cost and other complexities, nonlinear analysis is a practical and valuable tool for the design of LWR components, especially under ASME Level D service conditions (faulted conditions) and it will greatly assist in the evaluation of ductile fracture potential of pressure boundary components. Since the nonlinear behavior is generally a local phenomenon, the design of complex components can be accomplished through substructuring isolated localized regions and evaluating them in detail using nonlinear analysis methods

  1. Technical and economic working domains of industrial heat pumps: Part 2 - ammonia-water hybrid absorption-compression heat pumps

    DEFF Research Database (Denmark)

    Jensen, Jonas Kjær; Ommen, Torben Schmidt; Markussen, Wiebke Brix

    2015-01-01

    The ammonia-water hybrid absorption-compression heat pump (HACHP) has been proposed as a relevant technology for industrial heat supply, especially for high sink temperatures and high temperature glides in the sink and source. This is due to the reduced vapour pressure and the non-isothermal phase...... change of the zeotropic mixture, ammonia-water. To evaluate to which extent these advantages can be translated into feasible heat pump solutions, the working domain of the HACHP is investigated based on technical and economic constraints. The HACHP working domain is compared to that of the best available...... vapour compression heat pump with natural working fluids. This shows that the HACHP increases the temperature lifts and heat supply temperatures that are feasible to produce with a heat pump. The HACHP is shown to be capable of delivering heat supply temperatures as high as 150 °C and temperature lifts...

  2. Technical and Economic Working Domains of Industrial Heat Pumps: Part 2 - Ammonia-Water Hybrid Absorption-Compression Heat Pumps

    DEFF Research Database (Denmark)

    Jensen, Jonas Kjær; Ommen, Torben Schmidt; Markussen, Wiebke Brix

    2014-01-01

    The ammonia-water hybrid absorption-compression heat pump (HACHP) is a relevant technology for industrial heat supply, especially for high sink temperatures and high temperature glides in the sink and source. This is due to the reduced vapour pressure and the non-isothermal phase change...... of the zeotropic mixture, ammonia-water. To evaluate to which extent these advantages can be translated into feasible heat pump solutions, the working domain of the HACHP is investigated based on technical and economic constraints. The HACHP working domain is compared to that of the best possible vapour...... compression heat pump with natural working fluids. This shows that the HACHP increases the temperature lifts and heat supply temperatures that are feasible to produce with a heat pump. The HACHP is shown to be capable of delivering heat supply temperatures as high as 140 XC and temperature lifts up to 60 K...

  3. A service component-based accounting and charging architecture to support interim mechanisms across multiple domains

    NARCIS (Netherlands)

    Le, M. van; Beijnum, B.J.F. van; Huitema, G.B.

    2004-01-01

    Today, telematics services are often compositions of different chargeable service components offered by different service providers. To enhance component-based accounting and charging, the service composition information is used to match with the corresponding charging structure of a service

  4. Agreement Coefficients as Indices of Dependability for Domain-Referenced Tests. ACT Technical Bulletin No. 28.

    Science.gov (United States)

    Kane, Michael T.; Brennan, Robert L.

    A large number of seemingly diverse coefficients have been proposed as indices of dependability, or reliability, for domain-referenced and/or mastery tests. In this paper, it is shown that most of these indices are special cases of two generalized indices of agreement: one that is corrected for chance, and one that is not. The special cases of…

  5. Probabilistic Structural Analysis Methods for select space propulsion system components (PSAM). Volume 3: Literature surveys and technical reports

    Science.gov (United States)

    1992-01-01

    The technical effort and computer code developed during the first year are summarized. Several formulations for Probabilistic Finite Element Analysis (PFEA) are described with emphasis on the selected formulation. The strategies being implemented in the first-version computer code to perform linear, elastic PFEA is described. The results of a series of select Space Shuttle Main Engine (SSME) component surveys are presented. These results identify the critical components and provide the information necessary for probabilistic structural analysis.

  6. A Service Component-based Accounting and Charging Architecture to Support Interim Mechanisms across Multiple Domains

    NARCIS (Netherlands)

    Le, V.M.; van Beijnum, Bernhard J.F.; Huitema, G.B.

    Today, telematics services are o Aen compositions of different chargeable service components offered by different service providers. To enhance component-based accounting and charging, the service composition information is used to match with the corresponding charging structure of a service

  7. Structure and Function of the Catalytic Domain of the Dihydrolipoyl Acetyltransferase Component in Escherichia coli Pyruvate Dehydrogenase Complex*

    Science.gov (United States)

    Wang, Junjie; Nemeria, Natalia S.; Chandrasekhar, Krishnamoorthy; Kumaran, Sowmini; Arjunan, Palaniappa; Reynolds, Shelley; Calero, Guillermo; Brukh, Roman; Kakalis, Lazaros; Furey, William; Jordan, Frank

    2014-01-01

    The Escherichia coli pyruvate dehydrogenase complex (PDHc) catalyzing conversion of pyruvate to acetyl-CoA comprises three components: E1p, E2p, and E3. The E2p is the five-domain core component, consisting of three tandem lipoyl domains (LDs), a peripheral subunit binding domain (PSBD), and a catalytic domain (E2pCD). Herein are reported the following. 1) The x-ray structure of E2pCD revealed both intra- and intertrimer interactions, similar to those reported for other E2pCDs. 2) Reconstitution of recombinant LD and E2pCD with E1p and E3p into PDHc could maintain at least 6.4% activity (NADH production), confirming the functional competence of the E2pCD and active center coupling among E1p, LD, E2pCD, and E3 even in the absence of PSBD and of a covalent link between domains within E2p. 3) Direct acetyl transfer between LD and coenzyme A catalyzed by E2pCD was observed with a rate constant of 199 s−1, comparable with the rate of NADH production in the PDHc reaction. Hence, neither reductive acetylation of E2p nor acetyl transfer within E2p is rate-limiting. 4) An unprecedented finding is that although no interaction could be detected between E1p and E2pCD by itself, a domain-induced interaction was identified on E1p active centers upon assembly with E2p and C-terminally truncated E2p proteins by hydrogen/deuterium exchange mass spectrometry. The inclusion of each additional domain of E2p strengthened the interaction with E1p, and the interaction was strongest with intact E2p. E2p domain-induced changes at the E1p active site were also manifested by the appearance of a circular dichroism band characteristic of the canonical 4′-aminopyrimidine tautomer of bound thiamin diphosphate (AP). PMID:24742683

  8. Structure and function of the catalytic domain of the dihydrolipoyl acetyltransferase component in Escherichia coli pyruvate dehydrogenase complex.

    Science.gov (United States)

    Wang, Junjie; Nemeria, Natalia S; Chandrasekhar, Krishnamoorthy; Kumaran, Sowmini; Arjunan, Palaniappa; Reynolds, Shelley; Calero, Guillermo; Brukh, Roman; Kakalis, Lazaros; Furey, William; Jordan, Frank

    2014-05-30

    The Escherichia coli pyruvate dehydrogenase complex (PDHc) catalyzing conversion of pyruvate to acetyl-CoA comprises three components: E1p, E2p, and E3. The E2p is the five-domain core component, consisting of three tandem lipoyl domains (LDs), a peripheral subunit binding domain (PSBD), and a catalytic domain (E2pCD). Herein are reported the following. 1) The x-ray structure of E2pCD revealed both intra- and intertrimer interactions, similar to those reported for other E2pCDs. 2) Reconstitution of recombinant LD and E2pCD with E1p and E3p into PDHc could maintain at least 6.4% activity (NADH production), confirming the functional competence of the E2pCD and active center coupling among E1p, LD, E2pCD, and E3 even in the absence of PSBD and of a covalent link between domains within E2p. 3) Direct acetyl transfer between LD and coenzyme A catalyzed by E2pCD was observed with a rate constant of 199 s(-1), comparable with the rate of NADH production in the PDHc reaction. Hence, neither reductive acetylation of E2p nor acetyl transfer within E2p is rate-limiting. 4) An unprecedented finding is that although no interaction could be detected between E1p and E2pCD by itself, a domain-induced interaction was identified on E1p active centers upon assembly with E2p and C-terminally truncated E2p proteins by hydrogen/deuterium exchange mass spectrometry. The inclusion of each additional domain of E2p strengthened the interaction with E1p, and the interaction was strongest with intact E2p. E2p domain-induced changes at the E1p active site were also manifested by the appearance of a circular dichroism band characteristic of the canonical 4'-aminopyrimidine tautomer of bound thiamin diphosphate (AP). © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

  9. Rapidly evolving zona pellucida domain proteins are a major component of the vitelline envelope of abalone eggs

    Science.gov (United States)

    Aagaard, Jan E.; Yi, Xianhua; MacCoss, Michael J.; Swanson, Willie J.

    2006-01-01

    Proteins harboring a zona pellucida (ZP) domain are prominent components of vertebrate egg coats. Although less well characterized, the egg coat of the non-vertebrate marine gastropod abalone (Haliotis spp.) is also known to contain a ZP domain protein, raising the possibility of a common molecular basis of metazoan egg coat structures. Egg coat proteins from vertebrate as well as non-vertebrate taxa have been shown to evolve under positive selection. Studied most extensively in the abalone system, coevolution between adaptively diverging egg coat and sperm proteins may contribute to the rapid development of reproductive isolation. Thus, identifying the pattern of evolution among egg coat proteins is important in understanding the role these genes may play in the speciation process. The purpose of the present study is to characterize the constituent proteins of the egg coat [vitelline envelope (VE)] of abalone eggs and to provide preliminary evidence regarding how selection has acted on VE proteins during abalone evolution. A proteomic approach is used to match tandem mass spectra of peptides from purified VE proteins with abalone ovary EST sequences, identifying 9 of 10 ZP domain proteins as components of the VE. Maximum likelihood models of codon evolution suggest positive selection has acted among a subset of amino acids for 6 of these genes. This work provides further evidence of the prominence of ZP proteins as constituents of the egg coat, as well as the prominent role of positive selection in diversification of these reproductive proteins. PMID:17085584

  10. Time-domain ultra-wideband radar, sensor and components theory, analysis and design

    CERN Document Server

    Nguyen, Cam

    2014-01-01

    This book presents the theory, analysis, and design of ultra-wideband (UWB) radar and sensor systems (in short, UWB systems) and their components. UWB systems find numerous applications in the military, security, civilian, commercial and medicine fields. This book addresses five main topics of UWB systems: System Analysis, Transmitter Design, Receiver Design, Antenna Design and System Integration and Test. The developments of a practical UWB system and its components using microwave integrated circuits, as well as various measurements, are included in detail to demonstrate the theory, analysis and design technique. Essentially, this book will enable the reader to design their own UWB systems and components. In the System Analysis chapter, the UWB principle of operation as well as the power budget analysis and range resolution analysis are presented. In the UWB Transmitter Design chapter, the design, fabrication and measurement of impulse and monocycle pulse generators are covered. The UWB Receiver Design cha...

  11. University of Maryland component of the Center for Multiscale Plasma Dynamics: Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Dorland, William [University of Maryland

    2014-11-18

    The Center for Multiscale Plasma Dynamics (CMPD) was a five-year Fusion Science Center. The University of Maryland (UMD) and UCLA were the host universities. This final technical report describes the physics results from the UMD CMPD.

  12. Modality and domain specific components in auditory and visual working memory tasks.

    Science.gov (United States)

    Lehnert, Günther; Zimmer, Hubert D

    2008-03-01

    In the tripartite model of working memory (WM) it is postulated that a unique part system-the visuo-spatial sketchpad (VSSP)-processes non-verbal content. Due to behavioral and neurophysiological findings, the VSSP was later subdivided into visual object and visual spatial processing, the former representing objects' appearance and the latter spatial information. This distinction is well supported. However, a challenge to this model is the question how spatial information from non-visual sensory modalities, for example the auditory one, is processed. Only a few studies so far have directly compared visual and auditory spatial WM. They suggest that the distinction of two processing domains--one for object and one for spatial information--also holds true for auditory WM, but that only a part of the processes is modality specific. We propose that processing in the object domain (the item's appearance) is modality specific, while spatial WM as well as object-location binding relies on modality general processes.

  13. Time-Domain Voltage Sag State Estimation Based on the Unscented Kalman Filter for Power Systems with Nonlinear Components

    Directory of Open Access Journals (Sweden)

    Rafael Cisneros-Magaña

    2018-06-01

    Full Text Available This paper proposes a time-domain methodology based on the unscented Kalman filter to estimate voltage sags and their characteristics, such as magnitude and duration in power systems represented by nonlinear models. Partial and noisy measurements from the electrical network with nonlinear loads, used as data, are assumed. The characteristics of voltage sags can be calculated in a discrete form with the unscented Kalman filter to estimate all the busbar voltages; being possible to determine the rms voltage magnitude and the voltage sag starting and ending time, respectively. Voltage sag state estimation results can be used to obtain the power quality indices for monitored and unmonitored busbars in the power grid and to design adequate mitigating techniques. The proposed methodology is successfully validated against the results obtained with the time-domain system simulation for the power system with nonlinear components, being the normalized root mean square error less than 3%.

  14. Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy

    International Nuclear Information System (INIS)

    Fischer, B M; Walther, M; Jepsen, P Uhd

    2002-01-01

    The far-infrared dielectric function of a wide range of organic molecules is dominated by vibrations involving a substantial fraction of the atoms forming the molecule and motion associated with intermolecular hydrogen bond vibrations. Due to their collective nature such modes are highly sensitive to the intra- and intermolecular structure and thus provide a unique fingerprint of the conformational state of the molecule and effects of its environment. We demonstrate the use of terahertz time-domain spectroscopy (THz-TDS) for recording the far-infrared (0.5-4.0 THz) dielectric function of the four nucleobases and corresponding nucleosides forming the building blocks of deoxyribose nucleic acid (DNA). We observe numerous distinct spectral features with large differences between the molecules in both frequency-dependent absorption coefficient and index of refraction. Assisted by results from density-functional calculations we interpret the origin of the observed resonances as vibrations of hydrogen bonds between the molecules

  15. Projects at the component development and integration facility. Quarterly technical progress report, April 1, 1994--June 30, 1994

    International Nuclear Information System (INIS)

    1994-01-01

    This quarterly technical progress report presents progress on the projects at the Component Development and Integration Facility (CDIF) during the third quarter of FY94. The CDIF is a major Department of Energy test facility in Butte, Montana, operated by MSE, Inc. Projects in progress include: Biomass Remediation Project; Heavy Metal-Contaminated Soil Project; MHD Shutdown; Mine Waste Technology Pilot Program; Plasma Projects; Resource Recovery Project; and Spray Casting Project

  16. Components Needed for the Design of a Sustainable Career and Technical Education Program

    Science.gov (United States)

    Lassiter, Vann Mizzelle

    2012-01-01

    As education has changed to meet the needs of society and has been shaped by the enactment of new laws, various aspects included under the massive umbrella of education have also changed to maintain momentum One such educational program is career and technical education (CTE). Changes to CTE have been made to continually meet the needs of all…

  17. Technical report of electronics shop characteristics of high speed electronics component, (1)

    International Nuclear Information System (INIS)

    Watanabe, Shin-ichi; Shiino, Kazuo.

    1975-01-01

    We must develop electronics circuits for high speed signals. The electronics components of the circuits make use of the special components. This report treats a pulse response of the electronics components (i.e. coaxial cable, connector, resistor, capacitor, diode, transistor) for high speed electronics. The results of this report was already applied constructions of high speed electronics circuits and experimental equipments of the High Energy Physics Division. (auth.)

  18. Alternative Feedstocks Program Technical and Economic Assessment: Thermal/Chemical and Bioprocessing Components

    Energy Technology Data Exchange (ETDEWEB)

    Bozell, J. J.; Landucci, R.

    1993-07-01

    This resource document on biomass to chemicals opportunities describes the development of a technical and market rationale for incorporating renewable feedstocks into the chemical industry in both a qualitative and quantitative sense. The term "renewable feedstock?s" can be defined to include a huge number of materials such as agricultural crops rich in starch, lignocellulosic materials (biomass), or biomass material recovered from a variety of processing wastes.

  19. Assessing soft skills components in science and technology programs within Malaysian Technical Universities

    OpenAIRE

    Kahirol Mohd Salleh; Nor Lisa Sulaiman; Mimi Mohaffyza Mohamad; Lai Chee Sern

    2017-01-01

    The workforce is a social environment where particular skills are essential in order for workers to perform well, have a competitive edge and succeed in their careers. A soft skill is one of the skills needed in every type of workplace setting. Soft skills include communication skills, collaboration skills, entrepreneurship, and others. Workplace need workers who are competent not only with technical skills but who also have soft skills. There is lack of literature discussion on the ...

  20. Segmented frequency-domain fluorescence lifetime measurements: minimizing the effects of photobleaching within a multi-component system.

    Science.gov (United States)

    Marwani, Hadi M; Lowry, Mark; Keating, Patrick; Warner, Isiah M; Cook, Robert L

    2007-11-01

    This study introduces a newly developed frequency segmentation and recombination method for frequency-domain fluorescence lifetime measurements to address the effects of changing fractional contributions over time and minimize the effects of photobleaching within multi-component systems. Frequency segmentation and recombination experiments were evaluated using a two component system consisting of fluorescein and rhodamine B. Comparison of experimental data collected in traditional and segmented fashion with simulated data, generated using different changing fractional contributions, demonstrated the validity of the technique. Frequency segmentation and recombination was also applied to a more complex system consisting of pyrene with Suwannee River fulvic acid reference and was shown to improve recovered lifetimes and fractional intensity contributions. It was observed that photobleaching in both systems led to errors in recovered lifetimes which can complicate the interpretation of lifetime results. Results showed clear evidence that the frequency segmentation and recombination method reduced errors resulting from a changing fractional contribution in a multi-component system, and allowed photobleaching issues to be addressed by commercially available instrumentation.

  1. Component failure-rate data with potential applicability to the hot experimental facility. Technical information

    International Nuclear Information System (INIS)

    Dexter, A.H.

    1980-12-01

    A literature search, that was aided by computer searches of a number of data bases, resulted in the compilation of approximately 1223 pieces of component failure-rate data under 136 subject categories. The data bank can be provided upon request as a punched-card deck or on magnetic tape

  2. The concept of the pedagogical system of the higher technical educational establishment: essential characteristics of its components

    Directory of Open Access Journals (Sweden)

    Ольга Петрівна Лучанінова

    2016-03-01

    Full Text Available The article discusses the essential characteristics of the components of the concept of modern educational system of higher technical educational institutions.We believe that the important role in organization of pedagogical system of the modern higher technical educational establishment belongs to qualitatively new approaches: humanistic and ideological, andragogical, facilitating, personal, cultural, diversificational, cordocentrism, systematic and activity approach, interactive.The concept of pedagogical system will be effective, if the main fundamentals of the Concept are included into the plans of pedagogical work of the higher educational establishments and their structural subdivisions; if the organizational and methodological facilities and studying and generalizing of the experience in organization of the pedagogical activities in the other higher educational establishments are prepared; if the scientific and methodological conferences, seminars, round-table discussion meetings, trainings and so on are organized and held; if we  promote active exchange of the theoretical and methodological aspects of the pedagogical system, of new approaches, forms and methods of the pedagogical activities; if we consider the questions of the Concept implementation at the meetings of the pedagogical work councils, educational and methodological commissions and the like.The offered authors Concept of the pedagogical system of the higher technical educational establishment should help the educators modulate the pedagogical process, involve various institutions and the society to the active participation in the educational and pedagogical process.

  3. Assessing soft skills components in science and technology programs within Malaysian Technical Universities

    Directory of Open Access Journals (Sweden)

    Kahirol Mohd Salleh

    2017-06-01

    Full Text Available The workforce is a social environment where particular skills are essential in order for workers to perform well, have a competitive edge and succeed in their careers. A soft skill is one of the skills needed in every type of workplace setting. Soft skills include communication skills, collaboration skills, entrepreneurship, and others. Workplace need workers who are competent not only with technical skills but who also have soft skills. There is lack of literature discussion on the perceptions of needed soft skills in the workplace. Therefore, this study aimed to close the gap in the literature concerning the perceptions of instructors and students in the area of soft skills especially in communication skills, collaboration skills, and entrepreneurship at the workplace. This study aims to decrease the divide in soft skills differences among instructors and students in higher learning institutions so that students have the opportunity to excel in their learning process. This study employs quantitative method specifically using survey as an instrument. The findings shows soft skills including communication, collaboration, and entrepreneurship skills are one of the aspects stressed by the students and instructors at higher learning institutions to ensure that graduates will be employable and competent in order to contribute to the nation development.

  4. Security Hardened Cyber Components for Nuclear Power Plants: Phase I SBIR Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Franusich, Michael D. [SpiralGen, Inc., Pittsburgh, PA (United States)

    2016-03-18

    SpiralGen, Inc. built a proof-of-concept toolkit for enhancing the cyber security of nuclear power plants and other critical infrastructure with high-assurance instrumentation and control code. The toolkit is based on technology from the DARPA High-Assurance Cyber Military Systems (HACMS) program, which has focused on applying the science of formal methods to the formidable set of problems involved in securing cyber physical systems. The primary challenges beyond HACMS in developing this toolkit were to make the new technology usable by control system engineers and compatible with the regulatory and commercial constraints of the nuclear power industry. The toolkit, packaged as a Simulink add-on, allows a system designer to assemble a high-assurance component from formally specified and proven blocks and generate provably correct control and monitor code for that subsystem.

  5. Statistical and time domain signal analysis of the thermal behaviour of wind turbine drive train components under dynamic operation conditions

    International Nuclear Information System (INIS)

    Nienhaus, K; Baltes, R; Bernet, C; Hilbert, M

    2012-01-01

    Gearboxes and generators are fundamental components of all electrical machines and the backbone of all electricity generation. Since the wind energy represents one of the key energy sources of the future, the number of wind turbines installed worldwide is rapidly increasing. Unlike in the past wind turbines are more often positioned in arctic as well as in desert like regions, and thereby exposed to harsh environmental conditions. Especially the temperature in those regions is a key factor that defines the design and choice of components and materials of the drive train. To optimize the design and health monitoring under varying temperatures it is important to understand the thermal behaviour dependent on environmental and machine parameters. This paper investigates the behaviour of the stator temperature of the double fed induction generator of a wind turbine. Therefore, different scenarios such as start of the turbine after a long period of no load, stop of the turbine after a long period of full load and others are isolated and analysed. For each scenario the dependences of the temperature on multiple wind turbine parameters such as power, speed and torque are studied. With the help of the regression analysis for multiple variables, it is pointed out which parameters have high impact on the thermal behaviour. Furthermore, an analysis was done to study the dependences in the time domain. The research conducted is based on 10 months of data of a 2 MW wind turbine using an adapted data acquisition system for high sampled data. The results appear promising, and lead to a better understanding of the thermal behaviour of a wind turbine drive train. Furthermore, the results represent the base of future research of drive trains under harsh environmental conditions, and it can be used to improve the fault diagnosis and design of electrical machines.

  6. Sanyo Technical Review, Vol 28, No. 1, April 1996. Special issue on components and devices

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    ;Contents: The Present and Future of the Key Components and Devices; PC-NTSC Scan Converter LSI; A Single-Chip video CD Decorder LSI; Digital Audio QPSK Demodulator LSI for Television Broadcasting by Satellite; Single Chip Microcomputer with Flash Electrical Erasable Progammable Read Only Memory; High-Element-Density Bipolar Process `VHF-IV`; Energy-Saving, High-Efficiency Audio Amplifer Hybrid IC STK426-000 Series; High-Breakdown-Voltage, High-Frequency Si Bipolar Transistors; 1.5-Megapixel Poly-Si TFT-LCD Module with a Fully Integrated Driving Circuit; LCD Color Filter Process Using Film Resist; Giant Magnetoresistance Materials for Ultra-high Density Magnetic Recording Heads; New-Type Crystalline Sollar Cell-Hit Structure; Hydrogen-Absorbing Alloy for Portable Fuel Cell; Prismatic Lithium Ion Battery; Rotary Compressor Using a Rare-Earth Magnet Brushless Motor; Surround LSI Using 1.6 micrometers BiCMOS Process; MR Head for HDD; RF-SAW Filter for Digtal AMPS; Capability of High-speed Back-up of OS-CON; and Lubricants and Material for Sliding Parts in Rotary Compressor for HFC Refrigerants.

  7. A survey of HK, HPt, and RR domains and their organization in two-component systems and phosphorelay proteins of organisms with fully sequenced genomes

    Directory of Open Access Journals (Sweden)

    Baldiri Salvado

    2015-08-01

    Full Text Available Two Component Systems and Phosphorelays (TCS/PR are environmental signal transduction cascades in prokaryotes and, less frequently, in eukaryotes. The internal domain organization of proteins and the topology of TCS/PR cascades play an important role in shaping the responses of the circuits. It is thus important to maintain updated censuses of TCS/PR proteins in order to identify the various topologies used by nature and enable a systematic study of the dynamics associated with those topologies. To create such a census, we analyzed the proteomes of 7,609 organisms from all domains of life with fully sequenced and annotated genomes. To begin, we survey each proteome searching for proteins containing domains that are associated with internal signal transmission within TCS/PR: Histidine Kinase (HK, Response Regulator (RR and Histidine Phosphotranfer (HPt domains, and analyze how these domains are arranged in the individual proteins. Then, we find all types of operon organization and calculate how much more likely are proteins that contain TCS/PR domains to be coded by neighboring genes than one would expect from the genome background of each organism. Finally, we analyze if the fusion of domains into single TCS/PR proteins is more frequently observed than one might expect from the background of each proteome. We find 50 alternative ways in which the HK, HPt, and RR domains are observed to organize into single proteins. In prokaryotes, TCS/PR coding genes tend to be clustered in operons. 90% of all proteins identified in this study contain just one of the three domains, while 8% of the remaining proteins combine one copy of an HK, a RR, and/or an HPt domain. In eukaryotes, 25% of all TCS/PR proteins have more than one domain. These results might have implications for how signals are internally transmitted within TCS/PR cascades. These implications could explain the selection of the various designs in alternative circumstances.

  8. MDEP Technical Report TR-CSWG-02. Technical Report on Lessons Learnt on Achieving Harmonisation of Codes and Standards for Pressure Boundary Components in Nuclear Power Plants

    International Nuclear Information System (INIS)

    2013-01-01

    qualification of NDE personnel. In the course of reviewing the results of the SDO's code-comparison project, the CSWG found that the similarities and differences between each county's code and standard varied considerably amongst different countries. For example, one country's code was almost identical to another country's code in technical areas while others contained vastly different requirements. Regardless of the similarities and differences, the CSWG found that each pressure-boundary code has been determined by each country to result in a component with an acceptable level of quality and safety. It should be recognised that the rules for component design is just one aspect of the entire component design and construction process addressed by a pressure-boundary code. In addition, there are also philosophical and cultural factors involved that play a major role in the overall quality of the design and construction of a pressure-boundary component. In other words, the implementation of the code requirements alone does not always provide a true representation of the component's quality and safety without consideration of these philosophical and cultural factors. Mixing different country's codes and standards requirements might be detrimental and should be carefully evaluated when attempted. A collaborative evaluation by knowledgeable experts in each code or standard is one approach that may enable the use of different countries' code requirements. Overall, the CSWG concludes that each country's pressure-boundary code provides the necessary design and construction requirements to produce components with an acceptable level of quality and safety when (1) the code is used in conjunction with its country's standard industry practice, (2) the code is supplemented with industry and regulatory guidance documents, and (3) the code is implemented in a manner consistent with its cultural and philosophical factors. Furthermore, the CSWG

  9. Progress in the domain of emissions tracking and environment radioactivity monitoring - Proceedings of the technical days organised by the SFRP Environment Section

    International Nuclear Information System (INIS)

    Calmet, Dominique; Calvez, Marianne; Rivasseau, Corinne Cea; Monfort, Marguerite; Manificat, Guillaume; Pierrard, Olivier; Couvez, Celine; Masson, Olivier; Bruno, Valerie; Renaud, Philippe; Genova, Zhana; Reynal, Nathalie; Le Coz, Eric; Tchilian, Nathalie; Diana, Jean-Jacques; Beguinel, Philippe; Cortes, Pierre; Puydarrieux, Stephane; Brun, Thierry; Devin, Patrick; Clavel, Benoit; Hemidy, Pierre-Yves; Gontier, Gilles; Delloye, Thierry; Mailliat, Alain; Ferreri, Giovanni; LECLERC, Elisabeth

    2015-11-01

    The Environment Section of the French Society of Radiation Protection (SFRP) organized a technical meeting on the progress made in the domain of emissions tracking and environment radioactivity monitoring. This document brings together the abstracts and the presentations (slides) of the different talks given at the meeting: 1 - Environment monitoring at the global, national and local scale: historical overview (Dominique CALMET, CEA); 2 - Evolution of radioactivity monitoring in the environment from 1960 to the present day (Guillaume MANIFICAT, IRSN); 3 - Euratom's legal framework (Zhana GENOVA, CTE); 4 - Main regulatory changes during the last decade (Nathalie REYNAL, ASN); 5 - Progress of standardization works on radioactive effluent emissions control and environment monitoring (Philippe BEGUINEL, BNEN); 6 - From operators' self-monitoring to ASN's inspections: a many components control system (Eric LE COZ, ASN); 7 - Control of effluents and emissions management at CEA Centres (Marianne CALVEZ, CEA); 8 - Liquid and gaseous effluents of ITER experimental facility: description and impacts (Pierre CORTES, IO); 9 - Effluents and emissions management strategy at AREVA NC La Hague facility (Stephane PUYDARRIEUX, AREVA); 10 - Radioactive effluents from nuclear facilities ongoing deconstruction: from dimensioning to real effluents (Benoit CLAVEL, EDF); 11 - Radionuclides decontamination process for liquid effluents using micro-algae at the laboratory scale (Corinne RIVASSEAU, CEA); 12 - Radioactive effluents from nuclear medicine services: management, monitoring and impact measurement methods (Nathalie TCHILIAN, ASN); 13 - Evolution history of effluents management and environment monitoring at the Solvay La Rochelle site (Thierry DELLOYE, SOLVAY); 14 - Different international approaches in effluents management and monitoring: example of French and German gaseous effluents - regulation, analyses, accounting rules (Jean-Jacques DIANA, ASN); 15 - Environment

  10. Technical and economic working domains of industrial heat pumps: Part 1 - single stage vapour compression heat pumps

    DEFF Research Database (Denmark)

    Ommen, Torben Schmidt; Jensen, Jonas Kjær; Markussen, Wiebke Brix

    2015-01-01

    A large amount of operational and economic constraints limit the applicability of heat pumps operated with natural working fluids. The limitations are highly dependent on the integration of heat source and sink streams. An evaluation of feasible operating conditions was carried out considering......, the transcritical R744 expands the working domain for low sink outlet temperatures....

  11. Water chemistry and corrosion control of cladding and primary circuit components. Proceedings of a technical committee meeting

    International Nuclear Information System (INIS)

    1999-12-01

    Corrosion is the principal life limiting degradation mechanism in nuclear steam supply systems, especially taking into account the trends to increase fuel burnup, thermal rate and cycle length. Primary circuit components of water cooled power reactors have an impact on Zr-based alloys behaviour due to crud (primary circuit corrosion products) formation, transport and deposition on heat transfer surfaces. Crud deposits influence water chemistry, radiation and thermal hydraulic conditions near cladding surface, and by this way-Zr-based alloy corrosion. During the last decade, significant improvements were achieved in the reduction of the corrosion and dose rates by changing the cladding material for one more resistant to corrosion or by the improvement of water chemistry conditions. However, taking into account the above mentioned tendency for heavier fuel duties, corrosion and water chemistry, control will remain a serious task to work with for nuclear power plant operators and scientists, as well as development of generally accepted corrosion model of Zr-based alloys in a water environment in a new millennium. Upon the recommendation of the International Working Group on Water Reactor Fuel Performance and Technology, water chemistry and corrosion of cladding and primary circuit components are in the focus of the IAEA activities in the area of fuel technology and performance. At present the IAEA performs two co-ordinated research projects (CRPs): on On-line High Temperature Monitoring of Water Chemistry and Corrosion (WACOL) and on Activity Transport in Primary Circuits. Two CRPs deal with hydrogen and hydride degradation of the Zr-based alloys. A state-of-the-art review entitled: 'Waterside Corrosion of Zirconium Alloys in Nuclear Power Plants' was published in 1998. Technical Committee meetings on the subject were held in 1985 (Cadarache, France), 1989 (Portland, USA), 1993 (Rez, Czech Republic). During the last few years extensive exchange of experience in

  12. An Evaluation of the Science Education Component of the Cross River State Science and Technical Education Project

    Science.gov (United States)

    Ekuri, Emmanuel Etta

    2012-01-01

    The Cross River State Science and Technical Education Project was introduced in 1992 by edict number 9 of 20 December 1991, "Cross River State Science and Technical Education Board Edit, 20 December, 1991", with the aim of improving the quality of science teaching and learning in the state. As the success of the project depends…

  13. Determining the von Mises stress power spectral density for frequency domain fatigue analysis including out-of-phase stress components

    Science.gov (United States)

    Bonte, M. H. A.; de Boer, A.; Liebregts, R.

    2007-04-01

    This paper provides a new formula to take into account phase differences in the determination of an equivalent von Mises stress power spectral density (PSD) from multiple random inputs. The obtained von Mises PSD can subsequently be used for fatigue analysis. The formula was derived for use in the commercial vehicle business and was implemented in combination with Finite Element software to predict and analyse fatigue failure in the frequency domain.

  14. Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain

    DEFF Research Database (Denmark)

    Midtgaard, Søren Fuglsang; Assenholt, Jannie; Jonstrup, Anette Thyssen

    2006-01-01

    The multisubunit eukaryotic exosome is an essential RNA processing and degradation machine. In its nuclear form, the exosome associates with the auxiliary factor Rrp6p, which participates in both RNA processing and degradation reactions. The crystal structure of Saccharomyces cerevisiae Rrp6p...... ribonucleotides and their bases. Finally, in vivo mutational studies show the importance of the domain contacts for the processing function of Rrp6p and highlight fundamental differences between the protein and its prokaryotic RNase D counterparts....

  15. Magnetic fusion energy plasma interactive and high heat flux components. Volume II. Technical assessment of the critical issues and problem areas in high heat flux materials and component development

    Energy Technology Data Exchange (ETDEWEB)

    Abdou, M.A.; Boyd, R.D.; Easor, J.R.; Gauster, W.B.; Gordon, J.D.; Mattas, R.F.; Morgan, G.D.; Ulrickson, M.A,; Watson, R.D.; Wolfer, W.G,

    1984-06-01

    A technical assessment of the critical issues and problem areas for high heat flux materials and components (HHFMC) in magnetic fusion devices shows these problems to be of critical importance for the successful operation of near-term fusion experiments and for the feasibility and attractiveness of long-term fusion reactors. A number of subgroups were formed to assess the critical HHFMC issues along the following major lines: (1) source conditions, (2) systems integration, (3) materials and processes, (4) thermal hydraulics, (5) thermomechanical response, (6) electromagnetic response, (7) instrumentation and control, and (8) test facilities. The details of the technical assessment are presented in eight chapters. The primary technical issues and needs for each area are highlighted.

  16. Magnetic fusion energy plasma interactive and high heat flux components. Volume II. Technical assessment of the critical issues and problem areas in high heat flux materials and component development

    International Nuclear Information System (INIS)

    Abdou, M.A.; Boyd, R.D.; Easor, J.R.

    1984-06-01

    A technical assessment of the critical issues and problem areas for high heat flux materials and components (HHFMC) in magnetic fusion devices shows these problems to be of critical importance for the successful operation of near-term fusion experiments and for the feasibility and attractiveness of long-term fusion reactors. A number of subgroups were formed to assess the critical HHFMC issues along the following major lines: (1) source conditions, (2) systems integration, (3) materials and processes, (4) thermal hydraulics, (5) thermomechanical response, (6) electromagnetic response, (7) instrumentation and control, and (8) test facilities. The details of the technical assessment are presented in eight chapters. The primary technical issues and needs for each area are highlighted

  17. Semantic Meaning in Attitudinal Lexemes in the Domain of Kesenangan (Joy in Indonesian: An Analysis of Meaning Components and Lexical Relation

    Directory of Open Access Journals (Sweden)

    Prima Gusti Yanti

    2017-04-01

    Full Text Available The attitudinal lexeme on the domain of kesenangan in Indonesia language has not shown such clear meaning relationship, for both the common and diagnostic meaning of the lexemes. Those lexemes have such circular definitions, confusing upon their use. This study is conducted using a qualitative research approach employing content analysis technique. The aim of this study is to find out lexical relation and semantic meaning in attitudinal lexeme in the domain of kesenangan (joy in Indonesian language. Data is collected from seven Indonesian dictionaries, two magazines, five newspapers, and six literary works. All data is analyzed using a component analysis in the semantic theory. The research findings show that fourteen (14 lexemes (senang, nikmat, enak, puas, asyik, sukacita, ria, bangga, lega, bahagia, gembira, girang, riang, and ceria of attitudinal lexemes are related with the domain of kesenangan. The result shows that hyponymy and synonymy lexical relations occur in the domain of kesenangan. Synonymy relation consists of near-synonymy and propositional synonymy. In this case, absolute synonymy is not found.

  18. Bacillus subtilis Two-Component System Sensory Kinase DegS Is Regulated by Serine Phosphorylation in Its Input Domain

    DEFF Research Database (Denmark)

    Jers, Carsten; Kobir, Ahasanul; Søndergaard, Elsebeth Oline

    2011-01-01

    Bacillus subtilis two-component system DegS/U is well known for the complexity of its regulation. The cytosolic sensory kinase DegS does not receive a single predominant input signal like most two-component kinases, instead it integrates a wide array of metabolic inputs that modulate its activity......S phosphorylation can be carried out by at least two B. subtilis Hanks-type kinases in vitro, and this stimulates the phosphate transfer towards DegU. The consequences of this process were studied in vivo, using phosphomimetic (Ser76Asp) and non-phosphorylatable (Ser76Ala) mutants of DegS. In a number...

  19. Operating experiences with heat-exchanging components of a semi-technical pilot plant for steam gasification of coal using heat from HTR

    International Nuclear Information System (INIS)

    Kirchhoff, R.; Heek, K.H. van

    1984-01-01

    within the framework of the PNP- Project, a semi-technical plant for the development of a process of coal gasification by means of nuclear heat was operated. Here gasification is for the first time implemented in a fluidized bed using heat of an electrically heated helium cycle at pressure up to 40 bar and temperatures normal for HTR. The plant serves for testing and developing various components as immersion heater, insulations, dosing devices, and for compiling sound data for further planning

  20. MDEP Technical Report TR-CSWG-03. Technical Report: fundamental attributes for the design and construction of reactor coolant pressure-boundary components

    International Nuclear Information System (INIS)

    2014-01-01

    The primary, long-term goal of MDEP's CSWG is to achieve international harmonisation of codes and standards for pressure boundary components in nuclear power plants that are important to reactor safety. The key to achieving harmonisation is to understand the extent of similarities and differences amongst the pressure boundary codes and standards used in various countries. To assist the CSWG in its long-term goals, several standards development organisations (SDOs) from various countries performed a comparison of their pressure boundary codes and standards to identify the extent of similarities and differences in code requirements and the reasons for their differences. This CSWG document provides the fundamental attributes which have been developed for the codes and standards used in the design and construction of reactor coolant pressure boundary components in nuclear power plants. The fundamental attributes are the basic concepts to be considered in the design, materials, fabrication, installation, examination, testing and over-pressure protection requirements for pressure boundary components

  1. Technical cost modelling for a novel semi-solid metal (SSM) casting processes for automotive component manufacturing

    CSIR Research Space (South Africa)

    Tlale, NS

    2008-09-01

    Full Text Available to predict the cost structure of a newly developed manufacturing process if it is to be considered by manufacturing enterprises for development to substitute a process that is in use. The costs of the new SSM technologies was established by technical cost...

  2. RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins

    International Nuclear Information System (INIS)

    Hoffman, D.W.; Query, C.C.; Golden, B.L.; White, S.W.; Keene, J.D.

    1991-01-01

    An RNA recognition motif (RRM) of ∼80 amino acids constitutes the core of RNA-binding domains found in a large family of proteins involved in RNA processing. The U1 RNA-binding domain of the A protein component of the human U1 small nuclear ribonucleoprotein (RNP), which encompasses the RRM sequence, was analyzed by using NMR spectroscopy. The domain of the A protein is a highly stable monomer in solution consisting of four antiparallel β-strands and two α-helices. The highly conserved RNP1 and RNP2 consensus sequences, containing residues previously suggested to be involved in nucleic acid binding, are juxtaposed in adjacent β-strands. Conserved aromatic side chains that are critical for RNA binding are clustered on the surface to the molecule adjacent to a variable loop that influences recognition of specific RNA sequences. The secondary structure and topology of the RRM are similar to those of ribosomal proteins L12 and L30, suggesting a distant evolutionary relationship between these two types of RNA-associated proteins

  3. Results from the electro-optic sensors domain of the materials and components for missiles innovation and technology partnership (phase 1)

    Science.gov (United States)

    Bray, Mark E.; Shears, Robert A.

    2013-10-01

    The Materials and Components for Missiles Innovation and Technology Partnership (ITP) is a research programme supporting research for guided weapons at Technology Readiness Levels 1 to 4. The Anglo-French initiative is supported by the DGA and the MoD, with matched funding from industry. A major objective is to foster projects which partner UK and French universities, SMEs and larger companies. The first projects started in January 2008 and the first phase completed in spring 2013. Providing funding is secured, the next phase of the programme is due to start later in 2013. Selex ES leads Domain 3 of the MCM-ITP which develops Electro-Optic sensor technology. In collaboration with DGA, MoD and MBDA, the prime contractor, we identified 4 key objectives for the first ITP phase and focussed resources on achieving these. The objectives were to enable better imagery, address operationally stressing scenarios, provide low overall through life cost and improve active and semi-active sensors Nine normal projects and one ITP innovation fund project have been supported within the domain. The technology providers have included 3 SMEs and 8 research centres from both the United Kingdom and France. Highlights of the projects are included. An outline of the priorities for the domain for the new phase ise provided and we encourage organisations with suitable technology to contact us to get involved.

  4. Technical Note: Insertion of digital lesions in the projection domain for dual-source, dual-energy CT.

    Science.gov (United States)

    Ferrero, Andrea; Chen, Baiyu; Li, Zhoubo; Yu, Lifeng; McCollough, Cynthia

    2017-05-01

    To compare algorithms performing material decomposition and classification in dual-energy CT, it is desirable to know the ground truth of the lesion to be analyzed in real patient data. In this work, we developed and validated a framework to insert digital lesions of arbitrary chemical composition into patient projection data acquired on a dual-source, dual-energy CT system. A model that takes into account beam-hardening effects was developed to predict the CT number of objects with known chemical composition. The model utilizes information about the x-ray energy spectra, the patient/phantom attenuation, and the x-ray detector energy response. The beam-hardening model was validated on samples of iodine (I) and calcium (Ca) for a second-generation dual-source, dual-energy CT scanner for all tube potentials available and a wide range of patient sizes. The seven most prevalent mineral components of renal stones were modeled and digital stones were created with CT numbers computed for each patient/phantom size and x-ray energy spectra using the developed beam-hardening model. Each digital stone was inserted in the dual-energy projection data of a water phantom scanned on a dual-source scanner and reconstructed with the routine algorithms in use in our practice. The geometry of the forward projection for dual-energy data was validated by comparing CT number accuracy and high-contrast resolution of simulated dual-energy CT data of the ACR phantom with experimentally acquired data. The beam-hardening model and forward projection method accurately predicted the CT number of I and Ca over a wide range of tube potentials and phantom sizes. The images reconstructed after the insertion of digital kidney stones were consistent with the images reconstructed from the scanner, and the CT number ratios for different kidney stone types were consistent with data in the literature. A sample application of the proposed tool was also demonstrated. A framework was developed and validated

  5. Magnetic fusion energy plasma interactive and high heat flux components. Volume I. Technical assessment of the critical issues and problem areas in the plasma materials interaction field

    International Nuclear Information System (INIS)

    Conn, R.W.; Gauster, W.B.; Heifetz, D.; Marmar, E.; Wilson, K.L.

    1984-01-01

    A technical assessment of the critical issues and problem areas in the field of plasma materials interactions (PMI) in magnetic fusion devices shows these problems to be central for near-term experiments, for intermediate-range reactor devices including D-T burning physics experiments, and for long-term reactor machines. Critical technical issues are ones central to understanding and successful operation of existing and near-term experiments/reactors or devices of great importance for the long run, i.e., ones which will require an extensive, long-term development effort and thus should receive attention now. Four subgroups were formed to assess the critical PMI issues along four major lines: (1) PMI and plasma confinement physics experiments; (2) plasma-edge modelling and theory; (3) surface physics; and (4) materials technology for in-vessel components and the first wall. The report which follows is divided into four major sections, one for each of these topics

  6. Two Components of Aversive Memory in Drosophila, Anesthesia-Sensitive and Anesthesia-Resistant Memory, Require Distinct Domains Within the Rgk1 Small GTPase.

    Science.gov (United States)

    Murakami, Satoshi; Minami-Ohtsubo, Maki; Nakato, Ryuichiro; Shirahige, Katsuhiko; Tabata, Tetsuya

    2017-05-31

    Multiple components have been identified that exhibit different stabilities for aversive olfactory memory in Drosophila These components have been defined by behavioral and genetic studies and genes specifically required for a specific component have also been identified. Intermediate-term memory generated after single cycle conditioning is divided into anesthesia-sensitive memory (ASM) and anesthesia-resistant memory (ARM), with the latter being more stable. We determined that the ASM and ARM pathways converged on the Rgk1 small GTPase and that the N-terminal domain-deleted Rgk1 was sufficient for ASM formation, whereas the full-length form was required for ARM formation. Rgk1 is specifically accumulated at the synaptic site of the Kenyon cells (KCs), the intrinsic neurons of the mushroom bodies, which play a pivotal role in olfactory memory formation. A higher than normal Rgk1 level enhanced memory retention, which is consistent with the result that Rgk1 suppressed Rac-dependent memory decay; these findings suggest that rgk1 bolsters ASM via the suppression of forgetting. We propose that Rgk1 plays a pivotal role in the regulation of memory stabilization by serving as a molecular node that resides at KC synapses, where the ASM and ARM pathway may interact. SIGNIFICANCE STATEMENT Memory consists of multiple components. Drosophila olfactory memory serves as a fundamental model with which to investigate the mechanisms that underlie memory formation and has provided genetic and molecular means to identify the components of memory, namely short-term, intermediate-term, and long-term memory, depending on how long the memory lasts. Intermediate memory is further divided into anesthesia-sensitive memory (ASM) and anesthesia-resistant memory (ARM), with the latter being more stable. We have identified a small GTPase in Drosophila , Rgk1, which plays a pivotal role in the regulation of olfactory memory stability. Rgk1 is required for both ASM and ARM. Moreover, N

  7. The Hybrid Design: Integrating the Human and Technical Components of Just-In-Time Knowledge Management Systems

    Directory of Open Access Journals (Sweden)

    Nabie Y. Conteh

    2011-06-01

    Full Text Available This paper explores the right balance of human and technical resources in the design of Just-in-Time knowledge delivery. It also examines and analyzes the case study: “Teltech: The business of Knowledge Management” by Davenport. It further attempts to depict the characteristics of the hybrid. The paper describes how the hybrid can be applied to Just-In-Time knowledge delivery. It also seeks to analyze and explore its interplay with knowledge splits with a view to designing Just-In- Time Knowledge Management. These include: “tacit versus explicit knowledge”, “in-process” versus “after action” documentation, “process-centered versus product-centered approach”, “knowledge versus information” and the “culture of sharing versus hoarding.”

  8. Potyvirus helper component-proteinase self-interaction in the yeast two-hybrid system and delineation of the interaction domain involved.

    Science.gov (United States)

    Urcuqui-Inchima, S; Walter, J; Drugeon, G; German-Retana, S; Haenni, A L; Candresse, T; Bernardi, F; Le Gall, O

    1999-05-25

    Using the yeast two-hybrid system, a screen was performed for possible interactions between the proteins encoded by the 5' region of potyviral genomes [P1, helper component-proteinase (HC-Pro), and P3]. A positive self-interaction involving HC-Pro was detected with lettuce mosaic virus (LMV) and potato virus Y (PVY). The possibility of heterologous interaction between the HC-Pro of LMV and of PVY was also demonstrated. No interaction involving either the P1 or the P3 proteins was detected. A series of ordered deletions from either the N- or C-terminal end of the LMV HC-Pro was used to map the domain involved in interaction to the 72 N-terminal amino acids of the protein, a region known to be dispensable for virus viability but necessary for aphid transmission. A similar but less detailed analysis mapped the interacting domain to the N-terminal half of the PVY HC-Pro. Copyright 1999 Academic Press.

  9. Proposal for the Award of Two Contracts for the Technical Services for Work on Components of CERN Particle Accelerators and High Energy Physics Experiments

    CERN Document Server

    2003-01-01

    This document concerns the award of two contracts for the technical services for work on components of CERN particle accelerators and high energy physics experiments. Following a market survey carried out among 73 firms in fourteen Member States, a call for tenders (IT-3156/SPL) was sent on 4 November 2002 to three consortia in four Member States. By the closing date, CERN had received tenders from the three consortia. The Finance Committee is invited to agree to the negotiation of two contracts with: 1) the consortium SERCO FACILITIES MANAGEMENT (NL) - GERARD PERRIER INDUSTRIE (FR) - INEO ALPES (FR), the lowest bidder, for approximately 55% of the technical services for work on components of CERN particle accelerators and high energy physics experiments, for an initial period of five years and for a total amount not exceeding 37 435 270 euros (54 902 500 Swiss francs), subject to revision for inflation from 1 January 2005. The contract will include options for two one-year extensions beyond the initial five-...

  10. Development of a train-to-proficiency curriculum for the technical skills component of the fundamentals of endoscopic surgery exam.

    Science.gov (United States)

    Gearhart, Susan; Marohn, Michael; Ngamruengphong, Saowanee; Adrales, Gina; Owodunni, Oluwafemi; Duncan, Kim; Petrusa, Emil; Lipsett, Pamela

    2018-01-08

    The demonstration of competency in endoscopy is required prior to obtaining American Board of Surgery Certification. To demonstrate competency, the resident must pass a national high-stakes cognitive test and a technical skills exam on a virtual reality simulator. The purpose of this preliminary study was to design a proficiency-based endoscopy simulation curriculum to meet this competency requirement. This is a mixed methods prospective cohort study at a single academic medical institution. Prior to taking the national exam, surgery residents were required to participate in a skills lab and demonstrate proficiency on 10 simulation tasks. Proficiency was based on time and percent of objects targeted/mucosa seen. Simulation practice time, number of task repetitions to proficiency, and prior endoscopic experience were recorded. Resident's self-reported confidence scores in endoscopic skills prior to and following simulation lab training were obtained. From January 1, 2016 through August 1, 2017, 20 surgical residents (8 PGY2, 8 PGY3, 4 PGY4) completed both a faculty-supervised endoscopy skills lab and independent learning with train-to-proficiency simulation tasks. Median overall simulator time per resident was 306 min (IQR: 247-405 min). Median overall time to proficiency in all tasks was 235 min (IQR: 208-283 min). The median time to proficiency decreased with increasing PGY status (r = 0.4, P = 0.05). There was no correlation between prior real-time endoscopic experience and time to proficiency. Reported confidence in endoscopic skills increased significantly from mean of 5.75 prior to 7.30 following the faculty-supervised endoscopy skills lab (P = 0.0002). All 20 residents passed the national exam. In this preliminary study, a train-to-proficiency curriculum in endoscopy improved surgical resident's confidence in their endoscopic skills and 100% of residents passed the FES technical skills test on their first attempt. Our findings also indicate

  11. Delusions in first-episode psychosis: Principal component analysis of twelve types of delusions and demographic and clinical correlates of resulting domains.

    Science.gov (United States)

    Paolini, Enrico; Moretti, Patrizia; Compton, Michael T

    2016-09-30

    Although delusions represent one of the core symptoms of psychotic disorders, it is remarkable that few studies have investigated distinct delusional themes. We analyzed data from a large sample of first-episode psychosis patients (n=245) to understand relations between delusion types and demographic and clinical correlates. First, we conducted a principal component analysis (PCA) of the 12 delusion items within the Scale for the Assessment of Positive Symptoms (SAPS). Then, using the domains derived via PCA, we tested a priori hypotheses and answered exploratory research questions related to delusional content. PCA revealed five distinct components: Delusions of Influence, Grandiose/Religious Delusions, Paranoid Delusions, Negative Affect Delusions (jealousy, and sin or guilt), and Somatic Delusions. The most prevalent type of delusion was Paranoid Delusions, and such delusions were more common at older ages at onset of psychosis. The level of Delusions of Influence was correlated with the severity of hallucinations and negative symptoms. We ascertained a general relationship between different childhood adversities and delusional themes, and a specific relationship between Somatic Delusions and childhood neglect. Moreover, we found higher scores on Delusions of Influence and Negative Affect Delusions among cannabis and stimulant users. Our results support considering delusions as varied experiences with varying prevalences and correlates. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  12. Ripples and the formation of anisotropic lipid domains: Imaging two-component double bilayers by atomic force microscopy_copy_03

    DEFF Research Database (Denmark)

    Leidy, C.; Kaasgaard, Thomas; Crowe, J.H.

    2002-01-01

    by atomic force microscopy, we investigated the origin of these anisotropic lipid domain patterns, and found that ripple phase formation is directly responsible for the anisotropic nature of these domains. The nucleation and growth of fluid-phase domains are found to be directed by the presence of ripples....... In particular, the fluid-phase domains elongate parallel to the ripples. The results show that ripple phase formation may have implications for domain formation in biological systems....

  13. The Arabidopsis KH-Domain RNA-Binding Protein ESR1 Functions in Components of Jasmonate Signalling, Unlinking Growth Restraint and Resistance to Stress.

    Directory of Open Access Journals (Sweden)

    Louise F Thatcher

    Full Text Available Glutathione S-transferases (GSTs play important roles in the protection of cells against toxins and oxidative damage where one Arabidopsis member, GSTF8, has become a commonly used marker gene for early stress and defense responses. A GSTF8 promoter fragment fused to the luciferase reporter gene was used in a forward genetic screen for Arabidopsis mutants with up-regulated GSTF8 promoter activity. This identified the esr1-1 (enhanced stress response 1 mutant which also conferred increased resistance to the fungal pathogen Fusarium oxysporum. Through positional cloning, the ESR1 gene was found to encode a KH-domain containing RNA-binding protein (At5g53060. Whole transcriptome sequencing of esr1-1 identified altered expression of genes involved in responses to biotic and abiotic stimuli, hormone signaling pathways and developmental processes. In particular was an overall significant enrichment for jasmonic acid (JA mediated processes in the esr1-1 down-regulated dataset. A subset of these genes were tested for MeJA inducibility and we found the expression of some but not all were reduced in esr1-1. The esr1-1 mutant was not impaired in other aspects of JA-signalling such as JA- sensitivity or development, suggesting ESR1 functions in specific components of the JA-signaling pathway. Examination of salicylic acid (SA regulated marker genes in esr1-1 showed no increase in basal or SA induced expression suggesting repression of JA-regulated genes is not due to antagonistic SA-JA crosstalk. These results define new roles for KH-domain containing proteins with ESR1 unlinking JA-mediated growth and defense responses.

  14. Mobile sequences in the pyruvate dehydrogenase complex, the E2 component, the catalytic domain and the 2-oxogluturate dehydrogenase complex of Azotobacter vinelandii, as detected by 600 MHz 1H-NMR spectroscopy

    International Nuclear Information System (INIS)

    Hanemaaijer, R.; Vervoort, J.; Westphal, A.H.; Kok, A. de.; Veeger, C.

    1988-01-01

    600 MHz 1 H-NMR spectroscopy demonstrates that the pyruvate dehydrogenase complex of Azotobacter vinelandii contains regions of the polypeptide chain with intramolecular mobility. This mobility is located in the E 2 component and can probably be ascribed to alanine-proline-rich regions that link the lipoyl sibdiomains to each other as well as to the E 1 and E 3 binding domain. In the catalytic domain of E 2 which is thought to form a compact, rigid core, also conformational flexibility is observed. It is conceivable that the N-terminal region of the catalytic domain, which contains many alanine residues, is responsible for the observed mobility. In the low-field region of the 1 H-NMR spectrum of E 2 specific resonances are found, which can be ascribed to mobile phenylalanine, histidine and/or tyrosine residues which are located in the E 1 and E 3 binding domain that links the lipoyl domain to the catalytic domain. In the 1 H-NMR spectrum of the intact complex, these resonances cannot be observed, indicating a decreased mobility of the E 1 and E 3 binding domain. (author). 24 refs.; 2 figs

  15. Magnetic Fusion Energy Plasma Interactive and High Heat Flux Components: Volume 5, Technical assessment of critical issues in the steady state operation of fusion confinement devices

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    Critical issues for the steady state operation of plasma confinement devices exist in both the physics and technology fields of fusion research. Due to the wide range and number of these issues, this technical assessment has focused on the crucial issues associated with the plasma physics and the plasma interactive components. The document provides information on the problem areas that affect the design and operation of a steady state ETR or ITER type confinement device. It discusses both tokamaks and alternative concepts, and provides a survey of existing and planned confinement machines and laboratory facilities that can address the identified issues. A universal definition of steady state operation is difficult to obtain. From a physics point of view, steady state is generally achieved when the time derivatives approach zero and the operation time greatly exceeds the characteristic time constants of the device. Steady state operation for materials depends on whether thermal stress, creep, fatigue, radiation damage, or power removal are being discussed. For erosion issues, the fluence and availability of the machine for continuous operation are important, assuming that transient events such as disruptions do not limit the component lifetimes. The panel suggests, in general terms, that steady state requires plasma operation from 100 to 1000 seconds and an availability of more than a few percent, which is similar to the expectations for an ETR type device. The assessment of critical issues for steady state operation is divided into four sections: physics issues; technology issues; issues in alternative concepts; and devices and laboratory facilities that can address these problems.

  16. Magnetic Fusion Energy Plasma Interactive and High Heat Flux Components: Volume 5, Technical assessment of critical issues in the steady state operation of fusion confinement devices

    International Nuclear Information System (INIS)

    1988-01-01

    Critical issues for the steady state operation of plasma confinement devices exist in both the physics and technology fields of fusion research. Due to the wide range and number of these issues, this technical assessment has focused on the crucial issues associated with the plasma physics and the plasma interactive components. The document provides information on the problem areas that affect the design and operation of a steady state ETR or ITER type confinement device. It discusses both tokamaks and alternative concepts, and provides a survey of existing and planned confinement machines and laboratory facilities that can address the identified issues. A universal definition of steady state operation is difficult to obtain. From a physics point of view, steady state is generally achieved when the time derivatives approach zero and the operation time greatly exceeds the characteristic time constants of the device. Steady state operation for materials depends on whether thermal stress, creep, fatigue, radiation damage, or power removal are being discussed. For erosion issues, the fluence and availability of the machine for continuous operation are important, assuming that transient events such as disruptions do not limit the component lifetimes. The panel suggests, in general terms, that steady state requires plasma operation from 100 to 1000 seconds and an availability of more than a few percent, which is similar to the expectations for an ETR type device. The assessment of critical issues for steady state operation is divided into four sections: physics issues; technology issues; issues in alternative concepts; and devices and laboratory facilities that can address these problems

  17. Domains and domain loss

    DEFF Research Database (Denmark)

    Haberland, Hartmut

    2005-01-01

    politicians and in the media, especially in the discussion whether some languages undergo ‘domain loss’ vis-à-vis powerful international languages like English. An objection that has been raised here is that domains, as originally conceived, are parameters of language choice and not properties of languages...

  18. Steady-state operation of magnetic fusion devices: Plasma control and plasma facing components. Report on the IAEA technical committee meeting held at Fukuoka, 25-29 October 1999

    International Nuclear Information System (INIS)

    Engelmann, F.

    2000-01-01

    An IAEA Technical Committee Meeting on Steady-State Operation of Magnetic Fusion Devices - Plasma Control and Plasma Facing Components was held at Fukuoka, Japan, from 25 to 29 October 1999. The meeting was the second IAEA Techical Committee Meeting on the subject, following the one held at Hefei, China, a year earlier. The meeting was attended by over 150 researchers from 10 countries

  19. TRANSLATING SERVICE TECHNICAL PROSE

    African Journals Online (AJOL)

    language. The Application of Technical Service. Prose. To form a good idea of the appl ication .... cost lives. In this particular domain, translators must have a sound technical ... These semantic ... another language and often, in doing so, changing its meaning. The words ..... He will hand out tasks to each translator and after.

  20. Training and technical assistance for compliance with beverage and physical activity components of New York City's regulations for early child care centers.

    Science.gov (United States)

    Kakietek, Jakub; Dunn, Lillian; O'Dell, Sarah Abood; Jernigan, Jan; Kettel Khan, Laura

    2014-10-16

    In 2006, the New York City Department of Health and Mental Hygiene (DOHMH) passed regulations for child care centers that established standards for beverages provided to children and set a minimum amount of time for daily physical activity. DOHMH offered several types of training and technical assistance to support compliance with the regulations. This article analyzes the association between training and technical assistance provided and compliance with the regulations in a sample of 174 group child care centers. Compliance was measured by using a site inventory of beverages stored on premises and a survey of centers' teachers regarding the amount of physical activity provided. Training and technical assistance measures were based on the DOHMH records of training and technical assistance provided to the centers in the sample and on a survey of center directors. Ordinal logistic regression was used to assess the association between training and technical assistance measures and compliance with the regulations. Measures of training related to physical activity the center received: the number of staff members who participated in Sport, Play and Active Recreation for Kids (SPARK) and other training programs in which a center participated were associated with better compliance with the physical activity regulations. Neither training nor technical assistance were associated with compliance with the regulations related to beverages. Increased compliance with regulations pertaining to physical activity was not related to compliance with beverage regulations. Future trainings should be targeted to the specific regulation requirements to increase compliance.

  1. Crystallization and preliminary X-ray diffraction analysis of the P3 RNA domain of yeast ribonuclease MRP in a complex with RNase P/MRP protein components Pop6 and Pop7

    International Nuclear Information System (INIS)

    Perederina, Anna; Esakova, Olga; Quan, Chao; Khanova, Elena; Krasilnikov, Andrey S.

    2009-01-01

    This article describes the first successful crystallization of components of eukaryotic ribonucleases P/MRP. Yeast RNase MRP RNA domain P3 was crystallized in a complex with the proteins Pop6 and Pop7; the crystals diffracted to 3.25 Å resolution. Eukaryotic ribonucleases P and MRP are closely related RNA-based enzymes which contain a catalytic RNA component and several protein subunits. The roles of the protein subunits in the structure and function of eukaryotic ribonucleases P and MRP are not clear. Crystals of a complex that included a circularly permuted 46-nucleotide-long P3 domain of the RNA component of Saccharomyces cerevisiae ribonuclease MRP and selenomethionine derivatives of the shared ribonuclease P/MRP protein components Pop6 (18.2 kDa) and Pop7 (15.8 kDa) were obtained using the sitting-drop vapour-diffusion method. The crystals belonged to space group P4 2 22 (unit-cell parameters a = b = 127.2, c = 76.8 Å, α = β = γ = 90°) and diffracted to 3.25 Å resolution

  2. Crystallization and preliminary X-ray diffraction analysis of the P3 RNA domain of yeast ribonuclease MRP in a complex with RNase P/MRP protein components Pop6 and Pop7.

    Science.gov (United States)

    Perederina, Anna; Esakova, Olga; Quan, Chao; Khanova, Elena; Krasilnikov, Andrey S

    2010-01-01

    Eukaryotic ribonucleases P and MRP are closely related RNA-based enzymes which contain a catalytic RNA component and several protein subunits. The roles of the protein subunits in the structure and function of eukaryotic ribonucleases P and MRP are not clear. Crystals of a complex that included a circularly permuted 46-nucleotide-long P3 domain of the RNA component of Saccharomyces cerevisiae ribonuclease MRP and selenomethionine derivatives of the shared ribonuclease P/MRP protein components Pop6 (18.2 kDa) and Pop7 (15.8 kDa) were obtained using the sitting-drop vapour-diffusion method. The crystals belonged to space group P4(2)22 (unit-cell parameters a = b = 127.2, c = 76.8 A, alpha = beta = gamma = 90 degrees ) and diffracted to 3.25 A resolution.

  3. Building the DAML Electronic Commerce Domain

    National Research Council Canada - National Science Library

    Anyiwo, David

    2001-01-01

    The project captured additional functional and technical requirements for collaboration and exchange in the electronics industry's value chain, and refined the eCommerce domain ontology requirements...

  4. Domain analysis

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2017-01-01

    The domain-analytic approach to knowledge organization (KO) (and to the broader field of library and information science, LIS) is outlined. The article reviews the discussions and proposals on the definition of domains, and provides an example of a domain-analytic study in the field of art studies....... Varieties of domain analysis as well as criticism and controversies are presented and discussed....

  5. Immunological evaluation in nonhuman primates of formulations based on the chimeric protein P64k-domain III of dengue 2 and two components of Neisseria meningitidis.

    Science.gov (United States)

    Valdés, Iris; Hermida, Lisset; Martín, Jorge; Menéndez, Tamara; Gil, Lázaro; Lazo, Laura; Castro, Jorge; Niebla, Olivia; López, Carlos; Bernardo, Lídice; Sánchez, Jorge; Romero, Yaremis; Martínez, Rafael; Guzmán, María G; Guillén, Gerardo

    2009-02-11

    The main problem in the development of successful vaccines against dengue based on recombinant proteins is the necessity to use potent adjuvants to reach a proper functional immune response. Our group reported the expression, characterization and immunological evaluation of the recombinant protein PD5, which contains the domain III of the Envelope protein from dengue 2 virus fused to the carrier protein P64k. This construct completely protected monkeys against viral challenge when the Freund's adjuvant was employed. Therefore, to define suitable formulations for human use, the present work relies on the evaluation of PD5, produced with a high purity and under GMP conditions, when formulated either with outer membrane vesicles (OMV) or the serogroup A capsular polysaccharide (CPS-A) from Neisseria meningitidis, both adsorbed on aluminium hydroxide. The antibody response to the formulation containing the CPS-A was clearly superior to that of the formulation with OMV. The experiment of in vivo protection supported this evidence, since only the group immunized with PD5 and CPS-A was partially protected upon viral challenge. This is the first study in which the polysaccharide A of N. meningitidis is successfully employed as adjuvant for viral antigens.

  6. Crystallization and X-ray diffraction analysis of the complement component-3 (C3) inhibitory domain of Efb from Staphylococcus aureus

    International Nuclear Information System (INIS)

    Hammel, Michal; Ramyar, Kasra X.; Spencer, Charles T.; Geisbrecht, Brian V.

    2006-01-01

    The crystallization and results of multiwavelength anomalous diffraction studies of a recombinant C3-inhibitory fragment of Efb from S. aureus are reported. The extracellular fibrinogen-binding protein (Efb) of Staphylococcus aureus is a multifunctional virulence factor capable of potent inhibition of complement component-3 (C3) activity in addition to its previously described fibrinogen-binding properties. A truncated recombinant form of Efb (Efb-C) that binds C3 has been overexpressed and purified and has been crystallized using the hanging-drop vapor-diffusion technique. Crystals of native Efb-C grew in the tetragonal space group P4 3 (unit-cell parameters a = b = 59.53, c = 46.63 Å) with two molecules in the asymmetric unit and diffracted well beyond 1.25 Å limiting Bragg spacing. To facilitate de novo phasing of the Efb-C crystals, two independent site-directed mutants were engineered in which either residue Ile112 or Val140 was replaced with methionine and crystals isomorphous to those of native Efb-C were reproduced using a seleno-l-methionine-labeled form of each mutant protein. Multiwavelength anomalous diffraction (MAD) data were collected on both mutants and analyzed for their phasing power toward solution and refinement of a high-resolution Efb-C crystal structure

  7. A Study on Dielectric Properties of Cadmium Sulfide-Zinc Sulfide Core-Shell Nanocomposites for Application as Nanoelectronic Filter Component in the Microwave Domain

    Science.gov (United States)

    Devi, Jutika; Datta, Pranayee

    2018-03-01

    Complex permittivities of cadmium sulfide (CdS), zinc sulfide (ZnS), and of cadmium sulfide-zinc sulfide (CdS/ZnS) core-shell nanoparticles embedded in a polyvinyl alcohol matrix (PVA) were measured in liquid phase using a VectorNetwork Analyzer in the frequency range of 500 MHz-10 GHz. These nanocomposites are modeled as an embedded capacitor, and their electric field distribution and polarization have been studied using COMSOL Multiphysics software. By varying the thickness of the shell and the number of inclusions, the capacitance values were estimated. It was observed that CdS, ZnS and CdS/ZnS core-shell nanoparticles embedded in a polyvinyl alcohol matrix show capacitive behavior. There is a strong influence of the dielectric properties in the capacitive behavior of the embedded nanocapacitor. The capping matrix, position and filling factors of nanoinclusions all affect the capacitive behavior of the tested nanocomposites. Application of the CdS, ZnS and CdS/ZnS core-shell nanocomposite as the passive low-pass filter circuit has also been investigated. From the present study, it has been found that CdS/ZnS core-shell nanoparticles embedded in PVA matrix are potential structures for application as nanoelectronic filter components in different areas of communication.

  8. Technical presentation

    CERN Document Server

    FI Department

    2008-01-01

    RADIOSPARES, the leading catalogue distributor of components (electronic, electrical, automation, etc.) and industrial supplies will be at CERN on Friday 3 October 2008 (Main Building, Room B, from 9.00 a.m. to 3.00 p.m.) to introduce its new 2008/2009 catalogue. This will be the opportunity for us to present our complete range of products in more detail: 400 000 part numbers available on our web site (Radiospares France, RS International, extended range of components from other manufacturers); our new services: quotations, search for products not included in the catalogue, SBP products (Small Batch Production: packaging in quantities adapted to customers’ requirements); partnership with our focus manufacturers; demonstration of the on-line purchasing tool implemented on our web site in conjunction with CERN. RADIOSPARES will be accompanied by representatives of FLUKE and TYCO ELECTRONICS, who will make presentations, demonstrate materials and answer any technical questio...

  9. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    Overview From a technical perspective, CMS has been in “beam operation” state since 6th November. The detector is fully closed with all components operational and the magnetic field is normally at the nominal 3.8T. The UXC cavern is normally closed with the radiation veto set. Access to UXC is now only possible during downtimes of LHC. Such accesses must be carefully planned, documented and carried out in agreement with CMS Technical Coordination, Experimental Area Management, LHC programme coordination and the CCC. Material flow in and out of UXC is now strictly controlled. Access to USC remains possible at any time, although, for safety reasons, it is necessary to register with the shift crew in the control room before going down.It is obligatory for all material leaving UXC to pass through the underground buffer zone for RP scanning, database entry and appropriate labeling for traceability. Technical coordination (notably Stephane Bally and Christoph Schaefer), the shift crew and run ...

  10. Concrete domains

    OpenAIRE

    Kahn, G.; Plotkin, G.D.

    1993-01-01

    This paper introduces the theory of a particular kind of computation domains called concrete domains. The purpose of this theory is to find a satisfactory framework for the notions of coroutine computation and sequentiality of evaluation.

  11. Prognostics for Microgrid Components

    Science.gov (United States)

    Saxena, Abhinav

    2012-01-01

    Prognostics is the science of predicting future performance and potential failures based on targeted condition monitoring. Moving away from the traditional reliability centric view, prognostics aims at detecting and quantifying the time to impending failures. This advance warning provides the opportunity to take actions that can preserve uptime, reduce cost of damage, or extend the life of the component. The talk will focus on the concepts and basics of prognostics from the viewpoint of condition-based systems health management. Differences with other techniques used in systems health management and philosophies of prognostics used in other domains will be shown. Examples relevant to micro grid systems and subsystems will be used to illustrate various types of prediction scenarios and the resources it take to set up a desired prognostic system. Specifically, the implementation results for power storage and power semiconductor components will demonstrate specific solution approaches of prognostics. The role of constituent elements of prognostics, such as model, prediction algorithms, failure threshold, run-to-failure data, requirements and specifications, and post-prognostic reasoning will be explained. A discussion on performance evaluation and performance metrics will conclude the technical discussion followed by general comments on open research problems and challenges in prognostics.

  12. Domain Engineering

    Science.gov (United States)

    Bjørner, Dines

    Before software can be designed we must know its requirements. Before requirements can be expressed we must understand the domain. So it follows, from our dogma, that we must first establish precise descriptions of domains; then, from such descriptions, “derive” at least domain and interface requirements; and from those and machine requirements design the software, or, more generally, the computing systems.

  13. The International Haemovigilance Network Database for the Surveillance of Adverse Reactions and Events in Donors and Recipients of Blood Components: technical issues and results.

    Science.gov (United States)

    Politis, C; Wiersum, J C; Richardson, C; Robillard, P; Jorgensen, J; Renaudier, P; Faber, J-C; Wood, E M

    2016-11-01

    The International Haemovigilance Network's ISTARE is an online database for surveillance of all adverse reactions (ARs) and adverse events (AEs) associated with donation of blood and transfusion of blood components, irrespective of severity or the harm caused. ISTARE aims to unify the collection and sharing of information with a view to harmonizing best practices for haemovigilance systems around the world. Adverse reactionss and adverse events are recorded by blood component, type of reaction, severity and imputability to transfusion, using internationally agreed standard definitions. From 2006 to 2012, 125 national sets of annual aggregated data were received from 25 countries, covering 132.8 million blood components issued. The incidence of all ARs was 77.5 per 100 000 components issued, of which 25% were severe (19.1 per 100 000). Of 349 deaths (0.26 per 100 000), 58% were due to the three ARs related to the respiratory system: transfusion-associated circulatory overload (TACO, 27%), transfusion-associated acute lung injury (TRALI, 19%) and transfusion-associated dyspnoea (TAD, 12%). Cumulatively, 594 477 donor complications were reported (rate 660 per 100 000), of which 2.9% were severe. ISTARE is a well-established surveillance tool offering important contributions to international efforts to maximize transfusion safety. © 2016 International Society of Blood Transfusion.

  14. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    Tuesday 30 March TECHNICAL TRAINING SEMINAR From 9:00 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Technical conferences: 09:00 - 12:00 Data acquisition systems on PCs. Industrial measurement and control techniques. 13:00 - 16:00 Advanced LabVIEW software and PXI instrumentation. Measuring instruments and system components for teststand automation. Introductory courses: 09:00 - 12:00 DIAdem: Data analysis and presentation 13:00 - 16:00 Data acquisition with LabVIEW Language: English and French Free special seminar. Registration is recommended with National Instruments Switzerland (please sp...

  15. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    Tuesday 30 March TECHNICAL TRAINING SEMINAR From 9:00 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Technical conferences: 09:00 - 12:00 Data acquisition systems on PCs. Industrial measurement and control techniques. 13:00 - 16:00 Advanced LabVIEW software and PXI instrumentation. Measuring instruments and system components for teststand automation. Introductory courses: 09:00 - 12:00 DIAdem: Data analysis and presentation 13:00 - 16:00 Data acquisition with LabVIEW Language: English and French Free special seminar. Registration is recommended with National Instruments Swi...

  16. A research project to develop and evaluate a technical education component on materials technology for orientation to space-age technology

    Science.gov (United States)

    Jacobs, J. A.

    1976-01-01

    A project was initiated to develop, implement, and evaluate a prototype component for self-pacing, individualized instruction on basic materials science. Results of this project indicate that systematically developed, self-paced instruction provides an effective means for orienting nontraditional college students and secondary students, especially minorities, to both engineering technology and basic materials science. In addition, students using such a system gain greater chances for mastering subject matter than with conventional modes of instruction.

  17. Technical note: validation of a motion analysis system for measuring the relative motion of the intermediate component of a tripolar total hip arthroplasty prosthesis.

    Science.gov (United States)

    Chen, Qingshan; Lazennec, Jean Yves; Guyen, Olivier; Kinbrum, Amy; Berry, Daniel J; An, Kai-Nan

    2005-07-01

    Tripolar total hip arthroplasty (THA) prosthesis had been suggested as a method to reduce the occurrence of hip dislocation and microseparation. Precisely measuring the motion of the intermediate component in vitro would provide fundamental knowledge for understanding its mechanism. The present study validates the accuracy and repeatability of a three-dimensional motion analysis system to quantitatively measure the relative motion of the intermediate component of tripolar total hip arthroplasty prostheses. Static and dynamic validations of the system were made by comparing the measurement to that of a potentiometer. Differences between the mean system-calculated angle and the angle measured by the potentiometer were within +/-1 degrees . The mean within-trial variability was less than 1 degrees . The mean slope was 0.9-1.02 for different angular velocities. The dynamic noise was within 1 degrees . The system was then applied to measure the relative motion of an eccentric THA prosthesis. The study shows that this motion analysis system provides an accurate and practical method for measuring the relative motion of the tripolar THA prosthesis in vitro, a necessary first step towards the understanding of its in vivo kinematics.

  18. Characterization and management of radioactive sodium and other reactor components as input data for the decommissioning of liquid metal-cooled fast reactors. A compilation of data produced of data produced by members of the IAEA technical working group on fast reactors (TWG-FR) at two consultancies and one technical committee meeting. Working material

    International Nuclear Information System (INIS)

    2002-01-01

    A number of liquid metal cooled fast reactors (LMFRs) are in operation and, some have already been shut down; other reactors will reach the end of their design lifetime in a few years and become candidates for decommissioning. It is unfortunate that little consideration was devoted to decommissioning of reactors at the plant design and construction stage. It is with this focus that the Technical Working Group on Fast Reactors (TWGFR) recommended that the IAEA organize the exchange of information on LMFRs decommissioning technology. It was pointed out that the decommissioning of small sodium-cooled reactors has shown that there are two basic differences between thermal and fast reactors decommissioning: on the one side, the treatment and disposal of radioactive sodium coolant, and on the other side, the management of reactor components, for which the structural materials are activated in depth by fast neutrons. To this end, a Technical Committee Meeting on Sodium Removal and Disposal from LMFRs in Normal Operation and in the framework of Decommissioning (Aix-en-Provence, France, November 1997) and two Consultancies on Decommissioning of the Kazakh BN-350 LMFR (Vienna, Austria, October 1996; Obninsk, Russian Federation, February 1998) were convened by the IAEA. These Meetings brought together a group of experts from France, Russia, Kazakhstan, the UK, and the USA to exchange information on, and to review current technical knowledge and experience in the management of radioactive coolant and reactor components following closing of LMFRs, as well as their design features and operating experience relevant for decommissioning procedures. The report provides general and detailed information on activation characteristics of the primary coolant; treatment and disposal of the spent sodium; removal of the residual sodium deposits and decontamination; the activation characteristics of the reactor components and the management of the latter. The recurring theme is finding

  19. Separating Cognitive and Content Domains in Mathematical Competence

    Science.gov (United States)

    Harks, Birgit; Klieme, Eckhard; Hartig, Johannes; Leiss, Dominik

    2014-01-01

    The present study investigates the empirical separability of mathematical (a) content domains, (b) cognitive domains, and (c) content-specific cognitive domains. There were 122 items representing two content domains (linear equations vs. theorem of Pythagoras) combined with two cognitive domains (modeling competence vs. technical competence)…

  20. Technical Note: On the impact of the incident electron beam energy on the primary dose component of flattening filter free photon beams.

    Science.gov (United States)

    Kuess, Peter; Georg, Dietmar; Palmans, Hugo; Lechner, Wolfgang

    2016-08-01

    For commercially available linear accelerators (Linacs), the electron energies of flattening filter free (FFF) and flattened (FF) beams are either identical or the electron energy of the FFF beam is increased to match the percentage depth dose curve (PDD) of the FF beam (in reference geometry). This study focuses on the primary dose components of FFF beams for both kinds of settings, studied on the same Linac. The measurements were conducted on a VersaHD Linac (Elekta, Crawley, UK) for both FF and FFF beams with nominal energies of 6 and 10 MV. In the clinical setting of the VersaHD, the energy of FFFM (Matched) beams is set to match the PDDs of the FF beams. In contrast the incident electron beam of the FFFU beam was set to the same energy as for the FF beam. Half value layers (HVLs) and a dual parameter beam quality specifier (DPBQS) were determined. For the 6 MV FFFM beam, HVL and DPBQS values were very similar compared to those of the 6 MV FF beam, while for the 10 MV FFFM and FF beams, only %dd(10)x and HVL values were comparable (differences below 1.5%). This shows that matching the PDD at one depth does not guarantee other beam quality dependent parameters to be matched. For FFFU beams, all investigated beam quality specifiers were significantly different compared to those for FF beams of the same nominal accelerator potential. The DPBQS of the 6 MV FF and FFFM beams was equal within the measurement uncertainty and was comparable to published data of a machine with similar TPR20,10 and %dd(10)x. In contrast to that, the DPBQS's two parameters of the 10 MV FFFM beam were substantially higher compared to those for the 10 MV FF beam. PDD-matched FF and FFF beams of both nominal accelerator potentials were observed to have similar HVL values, indicating similarity of their primary dose components. Using the DPBQS revealed that the mean attenuation coefficient was found to be the same within the uncertainty of 0.8% for 6 MV FF and 6 MV FFFM beams, while for 10 MV

  1. Technical Note: On the impact of the incident electron beam energy on the primary dose component of flattening filter free photon beams

    International Nuclear Information System (INIS)

    Kuess, Peter; Georg, Dietmar; Lechner, Wolfgang; Palmans, Hugo

    2016-01-01

    Purpose: For commercially available linear accelerators (Linacs), the electron energies of flattening filter free (FFF) and flattened (FF) beams are either identical or the electron energy of the FFF beam is increased to match the percentage depth dose curve (PDD) of the FF beam (in reference geometry). This study focuses on the primary dose components of FFF beams for both kinds of settings, studied on the same Linac. Methods: The measurements were conducted on a VersaHD Linac (Elekta, Crawley, UK) for both FF and FFF beams with nominal energies of 6 and 10 MV. In the clinical setting of the VersaHD, the energy of FFF M (Matched) beams is set to match the PDDs of the FF beams. In contrast the incident electron beam of the FFF U beam was set to the same energy as for the FF beam. Half value layers (HVLs) and a dual parameter beam quality specifier (DPBQS) were determined. Results: For the 6 MV FFF M beam, HVL and DPBQS values were very similar compared to those of the 6 MV FF beam, while for the 10 MV FFF M and FF beams, only %dd(10) x and HVL values were comparable (differences below 1.5%). This shows that matching the PDD at one depth does not guarantee other beam quality dependent parameters to be matched. For FFF U beams, all investigated beam quality specifiers were significantly different compared to those for FF beams of the same nominal accelerator potential. The DPBQS of the 6 MV FF and FFF M beams was equal within the measurement uncertainty and was comparable to published data of a machine with similar TPR 20,10 and %dd(10) x . In contrast to that, the DPBQS’s two parameters of the 10 MV FFF M beam were substantially higher compared to those for the 10 MV FF beam. Conclusions: PDD-matched FF and FFF beams of both nominal accelerator potentials were observed to have similar HVL values, indicating similarity of their primary dose components. Using the DPBQS revealed that the mean attenuation coefficient was found to be the same within the uncertainty of

  2. Technical note: A new wedge-shaped ionization chamber component module for BEAMnrc to model the integral quality monitoring system®

    Science.gov (United States)

    Oderinde, Oluwaseyi Michael; du Plessis, FCP

    2017-12-01

    The purpose of this study was to develop a new component module (CM) namely IQM to accurately model the integral quality monitoring (IQM) system® to be used in the BEAMnrc Monte Carlo (MC) code. The IQM is essentially a double wedge ionization chamber with the central electrode plate bisecting the wedge. The IQM CM allows the user to characterize the double wedge of this ionization chamber and BEAMnrc can then accurately calculate the dose in this CM including its enclosed air regions. This has been verified against measured data. The newly created CM was added into the standard BEAMnrc CMs, and it will be made available through the NRCC website. The BEAMnrc graphical user interface (GUI) and particle ray-tracing techniques were used to validate the IQM geometry. In subsequent MC simulations, the dose scored in the IQM was verified against measured data over a range of square fields ranging from 1 × 1-30 × 30 cm2. The IQM system is designed for the present day need for a device that could verify beam output in real-time during treatment. This CM is authentic, and it can serve as a basis for researchers that have an interest in real-time beam delivery checking using wedge-shaped ionization chamber based instruments like the IQM.

  3. Technical writing versus technical writing

    Science.gov (United States)

    Dillingham, J. W.

    1981-01-01

    Two terms, two job categories, 'technical writer' and 'technical author' are discussed in terms of industrial and business requirements and standards. A distinction between 'technical writing' and technical 'writing' is made. The term 'technical editor' is also considered. Problems inherent in the design of programs to prepare and train students for these jobs are discussed. A closer alliance between industry and academia is suggested as a means of preparing students with competent technical communication skills (especially writing and editing skills) and good technical skills.

  4. Subduction initiation and recycling of Alboran domain derived crustal components prior to the intra-crustal emplacement of mantle peridotites in the Westernmost Mediterranean: isotopic evidence from the Ronda peridotite

    Science.gov (United States)

    Varas-Reus, María Isabel; Garrido, Carlos J.; Bosch, Delphine; Marchesi, Claudio Claudio; Acosta-Vigil, Antonio; Hidas, Károly; Barich, Amel

    2014-05-01

    During Late Oligocene-Early Miocene different domains formed in the region between Iberia and Africa in the westernmost Mediterranean, including thinned continental crust and a Flysch Trough turbiditic deposits likely floored by oceanic crust [1]. At this time, the Ronda peridotite likely constituted the subcontinental lithospheric mantle of the Alboran domain, which mantle lithosphere was undergoing strong thinning and melting [2] [3] coevally with Early Miocene extension in the overlying Alpujárride-Maláguide stacked crust [4, 5]. Intrusive Cr- rich pyroxenites in the Ronda massif records the geochemical processes occurring in the subcontinental mantle of the Alboran domain during the Late Oligocene [6]. Recent isotopic studies of these pyroxenites indicate that their mantle source was contaminated by a subduction component released by detrital crustal sediments [6]. This new data is consistent with a subduction setting for the late evolution of the Alboran lithospheric mantle just prior to its final intracrustal emplacement in the early Miocene Further detailed structural studies of the Ronda plagioclase peridotites-related to the initial stages of ductile emplacement of the peridotite-have led to Hidas et al. [7] to propose a geodynamic model where folding and shearing of an attenuated mantle lithosphere occurred by backarc basin inversion followed by failed subduction initiation that ended into the intracrustal emplacement of peridotite into the Alboran wedge in the earliest Miocene. This hypothesis implies that the crustal component recorded in late, Cr-rich websterite dykes might come from underthrusted crustal rocks from the Flysch and/or Alpujárrides units that might have been involved in the earliest stages of this subduction initiation stage. To investigate the origin of crustal component in the mantle source of this late magmatic event recorded by Cr-pyroxenites, we have carried out a detail Sr-Nd-Pb-Hf isotopic study of a variety of Betic

  5. Non-technical skills in histopathology: definition and discussion.

    Science.gov (United States)

    Johnston, Peter W; Fioratou, Evie; Flin, Rhona

    2011-09-01

    Health care is a high-risk industry, with most documented adverse incidents being associated with 'human factors' including cognitive and social skills termed 'non-technical skills'. Non-technical skills complement the diagnostic and specialist skills and professional attributes required by medical practitioners, including histopathologists, and can enhance the quality of practice and delivery of health-care services and thus contribute to patient safety. This review aims to introduce histopathologists to non-technical skills and how these pertain to everyday histopathological practice. Drawing from other domains in medicine, specifically anaesthesia and surgery, a variety of non-technical skills are identified and described in the context of histopathology to illustrate the role each plays, often collectively, in daily practice. The generic non-technical skills are defined as situation awareness, decision-making, communication, teamwork, leadership, managing stress and coping with fatigue. Example scenarios from histopathology are presented and the contributions to outcomes made by non-technical skills are explained. Consideration of these specific non-technical skills as a component in histopathology training may benefit practitioners as well as assuring patient safety. © 2011 Blackwell Publishing Limited.

  6. Meta-domains for Automated System Identification

    National Research Council Canada - National Science Library

    Easley, Matthew; Bradley, Elizabeth

    2000-01-01

    .... In particular we introduce a new structure for automated model building known as a meta-domain which, when instantiated with domain-specific components tailors the space of candidate models to the system at hand...

  7. Domain crossing

    DEFF Research Database (Denmark)

    Schraefel, M. C.; Rouncefield, Mark; Kellogg, Wendy

    2012-01-01

    In CSCW, how much do we need to know about another domain/culture before we observe, intersect and intervene with designs. What optimally would that other culture need to know about us? Is this a “how long is a piece of string” question, or an inquiry where we can consider a variety of contexts a...

  8. Trusted Domain

    DEFF Research Database (Denmark)

    Hjorth, Theis Solberg; Torbensen, Rune

    2012-01-01

    remote access via IP-based devices such as smartphones. The Trusted Domain platform fits existing legacy technologies by managing their interoperability and access controls, and it seeks to avoid the security issues of relying on third-party servers outside the home. It is a distributed system...... of wireless standards, limited resources of embedded systems, etc. Taking these challenges into account, we present a Trusted Domain home automation platform, which dynamically and securely connects heterogeneous networks of Short-Range Wireless devices via simple non-expert user. interactions, and allows......In the digital age of home automation and with the proliferation of mobile Internet access, the intelligent home and its devices should be accessible at any time from anywhere. There are many challenges such as security, privacy, ease of configuration, incompatible legacy devices, a wealth...

  9. Methodology for technical risk assessment

    International Nuclear Information System (INIS)

    Waganer, L.M.; Zuckerman, D.S.

    1983-01-01

    A methodology has been developed for and applied to the assessment of the technical risks associated with an evolving technology. This methodology, originally developed for fusion by K. W. Billman and F. R. Scott at EPRI, has been applied to assess the technical risk of a fuel system for a fusion reactor. Technical risk is defined as the risk that a particular technology or component which is currently under development will not achieve a set of required technical specifications (i.e. probability of failure). The individual steps in the technical risk assessment are summarized. The first step in this methodology is to clearly and completely quantify the technical requirements for the particular system being examined. The next step is to identify and define subsystems and various options which appear capable of achieving the required technical performance. The subsystem options are then characterized regarding subsystem functions, interface requirements with the subsystems and systems, important components, developmental obstacles and technical limitations. Key technical subsystem performance parameters are identified which directly or indirectly relate to the system technical specifications. Past, existing and future technical performance data from subsystem experts are obtained by using a Bayesian Interrogation technique. The input data is solicited in the form of probability functions. Thus the output performance of the system is expressed as probability functions

  10. Imagining Technicities

    DEFF Research Database (Denmark)

    Liboriussen, Bjarke; Plesner, Ursula

    2011-01-01

    to the elements of taste and skill. In the final analysis those references were synthesized as five imagined technicities: the architect, the engineer, the client, the Chinese, and the Virtual World native. Because technicities are often assumed and rarely discussed as actants who influence practice, their role......, this article focuses on innovative uses of virtual worlds in architecture. We interviewed architects, industrial designers and other practitioners. Conceptually supported by an understanding of technicity found in Cultural Studies, the interviews were then coded with a focus on interviewees’ references...... in cooperation and development of ICTs seems to pass unnoticed. However, since they are aligned into ICTs, technicities impact innovation....

  11. Review of technical specifications

    International Nuclear Information System (INIS)

    Bedrich, M.; Scholz, D.

    1980-01-01

    The present paper deals with position and function of technical specifications before and during the manufacturing of reactor components, their structure and reasons for specific regulations due to safety philosophy and explains the cooperation of supplier, manufacturer, utilities and supervisory organizations. (RW)

  12. How to be an Effective Technical Writer?

    OpenAIRE

    M Solaiman Ali; Dheya Al-Othmany

    2012-01-01

    Abstract--This paper has focused on technical writing as a skill for engineers. It has sought to define technical writing and throw light on the content and technique of writing the various components of successful technical reports (for example, articles, papers, or research reports, such as theses and dissertations). Then, it has highlighted other special features and principles of effective technical writing. The material in this paper is divided into seven major parts. Part 1 (Technical w...

  13. The market for components

    International Nuclear Information System (INIS)

    Simon, M.; Stoelzl, D.

    1986-01-01

    The offers of the German nuclear components industry are shown at the examples of some masterpieces of engineering and their delivery capacities. Then, the success achieved with exports up to now are referred to. The forecast includes the demand, the side conditions of the technical competition, and the pricing and financing situation. (UA) [de

  14. Technical Network

    CERN Multimedia

    2007-01-01

    In order to optimize the management of the Technical Network (TN), to ease the understanding and purpose of devices connected to the TN, and to improve security incident handling, the Technical Network Administrators and the CNIC WG have asked IT/CS to verify the "description" and "tag" fields of devices connected to the TN. Therefore, persons responsible for systems connected to the TN will receive email notifications from IT/CS asking them to add the corresponding information in the network database. Thank you very much for your cooperation. The Technical Network Administrators & the CNIC WG

  15. Technical Network

    CERN Multimedia

    2007-01-01

    In order to optimise the management of the Technical Network (TN), to facilitate understanding of the purpose of devices connected to the TN and to improve security incident handling, the Technical Network Administrators and the CNIC WG have asked IT/CS to verify the "description" and "tag" fields of devices connected to the TN. Therefore, persons responsible for systems connected to the TN will receive e-mails from IT/CS asking them to add the corresponding information in the network database at "network-cern-ch". Thank you very much for your cooperation. The Technical Network Administrators & the CNIC WG

  16. Socio-technical security metrics

    NARCIS (Netherlands)

    Gollmann, D.; Herley, C.; Koenig, V.; Pieters, W.; Sasse, M.A.

    2015-01-01

    Report from Dagstuhl seminar 14491. This report documents the program and the outcomes of Dagstuhl Seminar 14491 “Socio-Technical Security Metrics”. In the domain of safety, metrics inform many decisions, from the height of new dikes to the design of nuclear plants. We can state, for example, that

  17. .Gov Domains API

    Data.gov (United States)

    General Services Administration — This dataset offers the list of all .gov domains, including state, local, and tribal .gov domains. It does not include .mil domains, or other federal domains outside...

  18. Impedance of accelerator components

    International Nuclear Information System (INIS)

    Corlett, J.N.

    1996-05-01

    As demands for high luminosity and low emittance particle beams increase, an understanding of the electromagnetic interaction of these beams with their vacuum chamber environment becomes more important in order to maintain the quality of the beam. This interaction is described in terms of the wake field in time domain, and the beam impedance in frequency domain. These concepts are introduced, and related quantities such as the loss factor are presented. The broadband Q = 1 resonator impedance model is discussed. Perturbation and coaxial wire methods of measurement of real components are reviewed

  19. Technical Note

    African Journals Online (AJOL)

    Administratör

    In this report on four patients, we did not use any of these techniques. The existence and the site of the fistulas was clearly demonstrated using basic but important preoperative detailed assessment and two intraoperative findings. The preoperative referral note that indicated the site of technical difficulty during the previous ...

  20. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    2010-01-01

    Operational Experience At the end of the first full-year running period of LHC, CMS is established as a reliable, robust and mature experiment. In particular common systems and infrastructure faults accounted for <0.6 % CMS downtime during LHC pp physics. Technical operation throughout the entire year was rather smooth, the main faults requiring UXC access being sub-detector power systems and rack-cooling turbines. All such problems were corrected during scheduled technical stops, in the shadow of tunnel access needed by the LHC, or in negotiated accesses or access extensions. Nevertheless, the number of necessary accesses to the UXC averaged more than one per week and the technical stops were inevitably packed with work packages, typically 30 being executed within a few days, placing a high load on the coordination and area management teams. It is an appropriate moment for CMS Technical Coordination to thank all those in many CERN departments and in the Collaboration, who were involved in CMS techni...

  1. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    2010-01-01

    Operational Experience Since the closure of the detector in February, the technical operation of CMS has been quite smooth and reliable. Some minor interventions in UXC were required to cure failures of power supplies, fans, readout boards and rack cooling connections, but all these failures were repaired in scheduled technical stops or parasitically during access dedicated to fixing LHC technical problems. The only occasion when CMS had to request an access between fills was to search for the source of an alarm from the leak-detection cables mounted in the DT racks. After a few minutes of diagnostic search, a leaking air-purge was found. Replacement was complete within 2 hours. This incident demonstrated once more the value of these leak detection cables; the system will be further extended (during the end of year technical stop) to cover more racks in UXC and the floor beneath the detector. The magnet has also been operating reliably and reacted correctly to the 14s power cut on 29 May (see below). In or...

  2. Technical endoscopy

    International Nuclear Information System (INIS)

    Cavalar, K.O.

    1988-01-01

    A survey is provided on different versions of endoscopes, taking into account the new developments of video endoscopy. With a variety of practical examples it is shown that technical tests using endoscopy are a demanding task for nondestructive testing, whose requirements can only be met on a customized basis. (orig./HP) [de

  3. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch Monday 9 February 2004 From 10:00 to 12:00 - IT Auditorium - bldg. 31, 3rd floor ANSOFT High-Frequency Seminar David Prestaux, Application Engineer, ANSOFT F-78535 BUC, France This Technical Training seminar will present two Ansoft application products: Ansoft HFSS and Ansoft Designer. Ansoft HFSS makes use of the Finite Element Method (FEM) to calculate field solutions from first principles. It can accurately predict all high-frequency behaviours such as dispersion, mode conversion, and losses due to materials and radiation. Ansoft Designer is a suite of design tools to fully integrate high-frequency, physics-based electromagnetic simulations into a seamless system-level simulation environment. Ansoft Designer uses a simple interface to give complete control over every design task, by a method allowing multiple solvers, Solver on Demand. • Introduction • Overview of the Ansoft Total solution • Ansoft HFSS 9...

  4. Other components

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    This chapter includes descriptions of electronic and mechanical components which do not merit a chapter to themselves. Other hardware requires mention because of particularly high tolerance or intolerance of exposure to radiation. A more systematic analysis of radiation responses of structures which are definable by material was given in section 3.8. The components discussed here are field effect transistors, transducers, temperature sensors, magnetic components, superconductors, mechanical sensors, and miscellaneous electronic components

  5. Technical challenges for dismantlement verification

    International Nuclear Information System (INIS)

    Olinger, C.T.; Stanbro, W.D.; Johnston, R.G.; Nakhleh, C.W.; Dreicer, J.S.

    1997-01-01

    In preparation for future nuclear arms reduction treaties, including any potential successor treaties to START I and II, the authors have been examining possible methods for bilateral warhead dismantlement verification. Warhead dismantlement verification raises significant challenges in the political, legal, and technical arenas. This discussion will focus on the technical issues raised by warhead arms controls. Technical complications arise from several sources. These will be discussed under the headings of warhead authentication, chain-of-custody, dismantlement verification, non-nuclear component tracking, component monitoring, and irreversibility. The authors will discuss possible technical options to address these challenges as applied to a generic dismantlement and disposition process, in the process identifying limitations and vulnerabilities. They expect that these considerations will play a large role in any future arms reduction effort and, therefore, should be addressed in a timely fashion

  6. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2011-01-01

    In this report we will review the main achievements of the Technical Stop and the progress of several centrally-managed projects to support CMS operation and maintenance and prepare the way for upgrades. Overview of the extended Technical Stop  The principal objectives of the extended Technical Stop affecting the detector itself were the installation of the TOTEM T1 telescopes on both ends, the readjustment of the alignment link-disk in YE-2, the replacement of the light-guide sleeves for all PMs of both HFs, and some repairs on TOTEM T2 and CASTOR. The most significant tasks were, however, concentrated on the supporting infrastructure. A detailed line-by-line leak search was performed in the C6F14 cooling system of the Tracker, followed by the installation of variable-frequency drives on the pump motors of the SS1 and SS2 tracker cooling plants to reduce pressure transients during start-up. In the electrical system, larger harmonic filters were installed in ...

  7. Formalization in Component Based Development

    DEFF Research Database (Denmark)

    Holmegaard, Jens Peter; Knudsen, John; Makowski, Piotr

    2006-01-01

    We present a unifying conceptual framework for components, component interfaces, contracts and composition of components by focusing on the collection of properties or qualities that they must share. A specific property, such as signature, functionality behaviour or timing is an aspect. Each aspect...... may be specified in a formal language convenient for its purpose and, in principle, unrelated to languages for other aspects. Each aspect forms its own semantic domain, although a semantic domain may be parameterized by values derived from other aspects. The proposed conceptual framework is introduced...

  8. Flow of catalyst particles in a flue gas desulfurization plant; mass transfer in the domain of a detached flow - two examples (desulfurization, HTGR type reactor) for the application of big computers solving technical problems

    International Nuclear Information System (INIS)

    Achenbach, E.

    1988-01-01

    The research work of the Institute for Reactor Components is mainly experimental in character. Where possible, the experiments are accompanied by numerical calculations. This has the advantage of rendering parameter studies faster and more economical than is the case with experiments, so that physical contexts can become more apparent. However, these calculations are no substitute for experiments. The application of numerical calculations in connection with experimental results can now be demonstrated with two examples. The examples have been selected with the aim of making the presentation of the results sufficiently interesting for all those participating at the colloquium. The theoretical and experimental results are presented in the form of short films. (orig.) [de

  9. Electronic components

    CERN Document Server

    Colwell, Morris A

    1976-01-01

    Electronic Components provides a basic grounding in the practical aspects of using and selecting electronics components. The book describes the basic requirements needed to start practical work on electronic equipment, resistors and potentiometers, capacitance, and inductors and transformers. The text discusses semiconductor devices such as diodes, thyristors and triacs, transistors and heat sinks, logic and linear integrated circuits (I.C.s) and electromechanical devices. Common abbreviations applied to components are provided. Constructors and electronics engineers will find the book useful

  10. Center for Technology for Advanced Scientific Component Software (TASCS)

    Energy Technology Data Exchange (ETDEWEB)

    Damevski, Kostadin [Virginia State Univ., Petersburg, VA (United States)

    2009-03-30

    A resounding success of the Scientific Discover through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedened computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS) tackles these issues by exploiting component-based software development to facilitate collaborative hig-performance scientific computing.

  11. INDOT Technical Training Plan : [Technical Summary

    Science.gov (United States)

    2012-01-01

    A wide range of job classifications, increasing technical : performance expectations, licensing and certification requirements, : budget restrictions and frequent department : reorganization has made technical training of employees : more difficult, ...

  12. TECHNICAL COORDINATION

    CERN Document Server

    A. Ball and W. Zeuner

    2013-01-01

    For the reporting period, the CMS common systems and infrastructure worked well, without failures that caused significant data losses. One more disconnection of the magnet cold box occurred in the shadow of interruptions in data taking, caused by a series of technical faults. The recognition during 2012 that re-connection can only safely be done at around 2 T implies a minimum magnet recovery time of 12 hours and raises serious concerns about the number of ramping cycles of the magnet these incidents cause. This has triggered studies of how to make the cryo-system of the magnet more robust against failures. The proton-proton run ended just before the end-of-year CERN closure, during which CASTOR was installed on the negative end of CMS and both ZDC calorimeters were installed in TAN absorbers the LHC tunnel, in preparation for the heavy-ion run. The installation of CASTOR was an excellent “engineering test” of procedures for working in an activated environment. Despite some technical pr...

  13. TECHNICAL COORDINATION

    CERN Multimedia

    Austin Ball

    Summary of progress since last CMS week. Ten years of construction work have been completed. CMS is closed, in very close to the ideal low luminosity configuration, and performed well in the first tests with LHC beam. Behind this encouraging news is the story of a summer of intense commitment by many teams (from the collaboration and 3 CERN departments) working together, against the clock and despite many minor setbacks, to ensure that the experiment was ready to play a leading role in the excitement of September 10. Following beampipe bakeout and refill with pure neon, a magnificent effort by the ECAL group and the pt 5 technical crew made it possible to install and commission all 4 ECAL endcap Dees before the end of August. In the shadow of this activity, the barrel and forward pixel trackers and part of the beam monitoring were installed within the vac tank. The pt 5 technical teams then succeeded in safely removing the 20t installation tables and their support blocks from beneath the already installed ...

  14. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2011-01-01

      Operational experience 2011 CMS is approaching the end of a very successful year of operation. Proton- proton running ended in the late afternoon of 30th October with a stunning 5.73 fb–1 delivered by LHC, of which CMS recorded 5.22 fb–1. During heavy-ion operation, which continues until 7th December, both the accelerator and the CMS detector have also performed very well. Despite the encouraging overall reliability of technical operation, several infrastructure failures which occurred since the last Bulletin are worthy of mention, with one leading for the first time to significant data-loss. On 10th July, a CERN-wide power failure brought down essentially all services including the magnet, due to an MCS setting being left in “manual” after the recent technical stop, but there was no significant damage and the detector was operational before the LHC, despite a slow and tortuous recovery (one of several indications this year that there is room for improve...

  15. Reengineering observatory operations for the time domain

    Science.gov (United States)

    Seaman, Robert L.; Vestrand, W. T.; Hessman, Frederic V.

    2014-07-01

    Observatories are complex scientific and technical institutions serving diverse users and purposes. Their telescopes, instruments, software, and human resources engage in interwoven workflows over a broad range of timescales. These workflows have been tuned to be responsive to concepts of observatory operations that were applicable when various assets were commissioned, years or decades in the past. The astronomical community is entering an era of rapid change increasingly characterized by large time domain surveys, robotic telescopes and automated infrastructures, and - most significantly - of operating modes and scientific consortia that span our individual facilities, joining them into complex network entities. Observatories must adapt and numerous initiatives are in progress that focus on redesigning individual components out of the astronomical toolkit. New instrumentation is both more capable and more complex than ever, and even simple instruments may have powerful observation scripting capabilities. Remote and queue observing modes are now widespread. Data archives are becoming ubiquitous. Virtual observatory standards and protocols and astroinformatics data-mining techniques layered on these are areas of active development. Indeed, new large-aperture ground-based telescopes may be as expensive as space missions and have similarly formal project management processes and large data management requirements. This piecewise approach is not enough. Whatever challenges of funding or politics facing the national and international astronomical communities it will be more efficient - scientifically as well as in the usual figures of merit of cost, schedule, performance, and risks - to explicitly address the systems engineering of the astronomical community as a whole.

  16. Technical bid evaluation

    International Nuclear Information System (INIS)

    Bruchhausen, E. v.

    1975-01-01

    It is shown which kind of problems arise for the owners of the project and what is the recommendable method of approach. A detailed description of the necessary working team, information in delegation of work and tasks of procedure, criteria of valuation and classification method. Examples of schemes are shown which are the basis of the technical bid evaluation: tables 'data of system/component' and 'scope of supply'. The procedure of normalization of the bids and of specifying the owners supplies are explained. The content of the final report is described. (HP) [de

  17. Technical knowledge creation

    DEFF Research Database (Denmark)

    Søberg, Peder Veng

    2017-01-01

    Purpose - The purpose of the paper is to amend shortcomings of existing theory concerning organizational learning and knowledge management. Design/methodology/approach – The paper reviews and refines existing theory. Findings - Findings from cognitive neuroscience suggest that technical knowledge...... domains essential for product development are largely nonlinguistic. Operations management/strategy tools enable the use of tacit knowledge in its tacit form and discourage premature standardization. Similarly, language use introduces standardization, which if introduced prematurely, causes incrementalism...... in line with findings from product development research. However, frameworks on organizational learning and knowledge management focus on language development and neglect use of tacit knowledge and the benefits involved with allowing elements of new product ideas to mature in a tacit form. Originality...

  18. Technical presentation

    CERN Multimedia

    GS Department

    2010-01-01

    10 March 2010 DYNEOS 10:00 – 12:00 - Main Building, Room B, 61-1-009 Dyneos AG is active in the fields of photonics, laser and high-precision positioning. Our highly qualified engineer team has more than 30 years of experience in electro-optical solutions sales. The engineers are supported by a technical and administrative team. We are focused on the Swiss market and represent six suppliers (Coherent, PI Physik Instrumente, SIOS, Nanonics Imaging, APE, Ekspla) in order to give a qualified sales and service support to our customers. Our products are dedicated to the research field as well as to industry. In addition to standard catalog products, we offer custom designs to fulfill the specific needs of OEM customers or specific applications.

  19. Technical presentation

    CERN Document Server

    FP Department

    2009-01-01

    07 April 2009 Technical presentation by Leuze Electronics: 14.00 – 15.00, Main Building, Room 61-1-017 (Room A) Photoelectric sensors, data identification and transmission systems, image processing systems. We at Leuze Electronics are "the sensor people": we have been specialising in optoelectronic sensors and safety technology for accident prevention for over 40 years. Our dedicated staff are all highly customer oriented. Customers of Leuze Electronics can always rely on one thing – on us! •\tFounded in 1963 •\t740 employees •\t115 MEUR turnover •\t20 subsidiaries •\t3 production facilities in southern Germany Product groups: •\tPhotoelectric sensors •\tIdentification and measurements •\tSafety devices

  20. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2010-01-01

    Overview Once again, the bulk of this article reviews the intense activity of a recently completed shutdown, which, although quite unforeseeable until a few weeks before it started, proved by its success that our often advertised capability to conduct major maintenance within a two month period is real. Although safely completed, on-time to remarkable precision, the activity was not without incident, and highlighted our dependence on many experienced, specialist teams and their precise choreography. Even after the yoke was safely closed, magnet re-commissioning and beampipe pumpdown showed new and thought-provoking behaviour. The struggle to maintain adequate technical resources will be a pre-occupation over the coming months, in parallel with the start of truly sustained operation, for which various procedures are still being put in place. Planning for future shutdowns must now become a high priority, with many working groups and task forces already in existence to prepare infrastructure improvements and to...

  1. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch Tuesday 3 February 2004 From 09:00 to 13:30 - Training Centre Auditorium - bldg. 593, room 11 USB (Universal Serial Bus) CYPRESS Seminar Claudia Colombini, Field Application Engineer CYPRESS ActiveComp Electronic GmbH D-85077 MANCHING, Germany As a pioneer in USB, CYPRESS sets the standard for cost-effective solutions without sacrificing functionality, performance or reliability. Having shipped over 200 million USB devices, Cypress is the undisputed market leader and demonstrates unmatched USB expertise. With the industry's broadest selection of USB solutions, Cypress has the right silicon, software and support for every USB application, from Low-speed to High-Speed and USB On-The-Go (OTG). 9:00 - 10:30 Overview of USB systems. USB CYPRESS product overview. Peripherals: Low Speed, Full Speed, High Speed (1.1 and 2.0). Hub Solutions, Embedded Host Solutions, On-The-Go (OTG) and wireless USB. USB Development Tools (first part) 10:30 -...

  2. FLAMMABLE GAS TECHNICAL BASIS DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    KRIPPS, L.J.

    2005-03-03

    This document describes the qualitative evaluation of frequency and consequences for DST and SST representative flammable gas accidents and associated hazardous conditions without controls. The evaluation indicated that safety-significant structures, systems and components (SSCs) and/or technical safety requirements (TSRs) were required to prevent or mitigate flammable gas accidents. Discussion on the resulting control decisions is included. This technical basis document was developed to support WP-13033, Tank Farms Documented Safety Analysis (DSA), and describes the risk binning process for the flammable gas representative accidents and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous condition based on an evaluation of the event frequency and consequence.

  3. Marketing information: The technical report as product

    Science.gov (United States)

    Stoher, F. F.; Pinelli, T. E.

    1981-01-01

    Technical reports constitute a product, the primary means for communicating the results of research to the user. The Langley scientific and technical information (STI) review and evaluation project undertook a review of the technical report as an effective product for information communication. Style manuals describing theory and practice in technical report preparation; publication manuals covering such factors as design, layout, and type style; and copies of technical reports were obtained from industrial, academic, governmental, and research organizations. Based on an analysis of this material, criteria will be established for the report components, for the relationship of the components within the report context, and for the overall report organization. The criteria will be used as bench marks and compared with the publication standards currently used to prepare NASA technical reports.

  4. TADS: Technical Assistance Development System.

    Science.gov (United States)

    Epting, Rosemary, Ed.

    Described is the Technical Assistance Development System (TADS), a component of the Frank Porter Graham Child Development Center of the University of North Carolina at Chapel Hill which offers support services to preschool demonstration centers for handicapped children in the First Chance Network. Discussed are the four types of services offered:…

  5. (ICT) to Technical Services in Libraries

    African Journals Online (AJOL)

    The term technical services is used in this paper to refer to the major operations that are common to all Technical Services Divisions in libraries – namely, cataloguing, classification, indexing and abstracting. These activities have many repetitive components which used to be done manually. But today the new technology ...

  6. Research Needs: Career and Technical Education

    Science.gov (United States)

    Kosloski, Michael F., Jr.; Ritz, John M.

    2016-01-01

    Research is an important component of each professional field. This study sought to determine topics that needed further research in the school subjects known as career and technical education. It determined topics that needed to be researched related to high school career and technical education (CTE) and the preparation for teaching CTE in…

  7. TECHNICAL COORDINATION

    CERN Multimedia

    Austin Ball

    2013-01-01

      Since the last report, much visible progress has been made, as the LS1 programme approaches the halfway point. From early October, technical and safety shift-crew have been present around the clock, allowing detectors to stay switched on overnight, ensuring that safety systems are operational and instructions for non-expert shift-crew are clear. LS1 progress Throughout the summer, whilst the solenoid vacuum tank and YB0 surfaces were accessible, an extensive installation programme took place to prepare for Tracker colder operation and the PLT installation, in 2014, the Phase 1 Pixel Tracker installation, in 2016–’17, and the HCAL Phase 1 upgrade completion, ending in LS2. This included pipework for N2 or dry air to flush the Tracker bulkhead region, many sensors to monitor temperature and dew point in the Tracker and its service channels, heating wires outside the Tracker cooling bundles, supports for the new vacuum-jacketed, concentric, CO2 Pixel cooling lines, the PLT cool...

  8. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2012-01-01

      UXC + detectors As explained in detail in the November 2011 bulletin, the bellows unit at −18.5 m from the CMS interaction point was identified as a prime candidate for the regularly occurring pressure spikes which occasionally led to sustained severe background conditions in 2011, affecting dead time and data quality. Similar regions in LHC with vacuum instabilities were observed to be close to bellows, which radiography showed to have distorted RF-fingers — on removal, they proved to have been severely overheated. The plans for the Year-End Technical Stop were adapted to prioritise radiography of the bellows at 16 m to 18 m either end of CMS. Excellent work by the beam pipe, survey and heavy mechanical teams allowed the X-rays to be taken as planned on 20th December, showing that the bellow at −18.5m had an obvious non-conformity. The RF-fingers were found inside the end of the opposing flared pipe instead of outside. In addition, the overlap between fingers and...

  9. Principal components

    NARCIS (Netherlands)

    Hallin, M.; Hörmann, S.; Piegorsch, W.; El Shaarawi, A.

    2012-01-01

    Principal Components are probably the best known and most widely used of all multivariate analysis techniques. The essential idea consists in performing a linear transformation of the observed k-dimensional variables in such a way that the new variables are vectors of k mutually orthogonal

  10. Technical innovation and management

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Yang Cheol

    1982-08-15

    This book gives explanations of the conception of technical innovation, development plan in Korea, connection between technology and a growth factor in national income, problem of technical innovation in developing country, analysis on cooperation between a developed country and a developing country, evaluation and strategy of technical development in Korea, technical innovation of industry, management of technical industry, analysis of special condition in Korea.

  11. Technical innovation and management

    International Nuclear Information System (INIS)

    Yoon, Yang Cheol

    1982-08-01

    This book gives explanations of the conception of technical innovation, development plan in Korea, connection between technology and a growth factor in national income, problem of technical innovation in developing country, analysis on cooperation between a developed country and a developing country, evaluation and strategy of technical development in Korea, technical innovation of industry, management of technical industry, analysis of special condition in Korea.

  12. A global reference model of the domain name system

    NARCIS (Netherlands)

    Koc, Y.; Jamakovic, A.; Gijsen, B.M.M.

    2012-01-01

    The domain name system (DNS) is a crucial component of the Internet. At this time, the DNS is facing major changes such as the introduction of DNSSEC and Internationalized Domain Name extensions (IDNs), the adoption of IPv6 and the upcoming extension of new generic top-level domains. These changes

  13. Technical normalization in the geoinformatics branch

    Directory of Open Access Journals (Sweden)

    Bronislava Horáková

    2006-09-01

    Full Text Available A basic principle of the technical normalisation is to hold the market development by developing unified technical rules for all concerned subjects. The information and communication technological industry is characterised by certain specific features contrary to the traditional industry. These features bring to the normalisation domain new demands, mainly the flexibility enabling to reflect the rapidly development market of ICT elastic way. The goal of the paper is to provide a comprehensive overview of the current process of technical normalization in the geoinformatic branch

  14. Research and Development Issues for Interactive Electronic Technical Manuals

    National Research Council Canada - National Science Library

    Ricci, Katrina

    2002-01-01

    ... technologies to support Interactive Electronic Technical Manuals (IETMs). A workshop was conducted at the NAVAIR Orlando, Training Systems Division to discuss the domain and to present current research in this area...

  15. TECHNICAL COORDINATION

    CERN Multimedia

    Austin Ball

    The 2008-9 CMS shutdown has reached its final phase. The yoke is closed again and the HFs are being prepared for lifting to beam height. Assuming no last minute problems occur, the detector will be ready for magnetic field tests by the end of June. The commitment of all the teams involved has ensured that an ambitious programme of work, including several tasks unforeseen in November 08, is nevertheless concluding on-time and successfully. All efforts are now being made to be ready for the CRAFT09 exercise. The way to proceed after CRAFT will depend on the LHC re-start schedule (to be clarified around the end of June). Options will be discussed during this CMS week. Shutdown 2008-9 Sub-Detectors As a reminder, the major shutdown activities on the detector components are listed below; details on each point can be found elsewhere in this bulletin. •    Installation and check-out of the Preshower detector on both endcaps •    Mainten...

  16. 22 CFR 120.10 - Technical data.

    Science.gov (United States)

    2010-04-01

    ... information in the public domain as defined in § 120.11. It also does not include basic marketing information... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Technical data. 120.10 Section 120.10 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.10...

  17. Social risk assessment of large technical systems

    NARCIS (Netherlands)

    Pasman, H.J.; Vrijling, J.K.

    2003-01-01

    A probabilistic approach to engineering advances. Since risk adhering to a technical structure can be determined quantitatively easier and more accurately than before, criteria for decision making are becoming more important. If the structure is in the public domain, and benefits are not felt, the

  18. Beamline standard component designs for the Advanced Photon Source

    International Nuclear Information System (INIS)

    Shu, D.; Barraza, J.; Brite, C.; Chang, J.; Sanchez, T.; Tcheskidov, V.; Kuzay, T.M.

    1994-01-01

    The Advanced Photon Source (APS) has initiated a design standardization and modularization activity for the APS synchrotron radiation beamline components. These standard components are included in components library, sub-components library and experimental station library. This paper briefly describes these standard components using both technical specifications and side view drawings

  19. Application of Component Scoring to a Complicated Cognitive Domain

    Science.gov (United States)

    1985-05-15

    Command (N-5) NAS Pensacola, FL 32508 Dr. John M. Eddins S..""*University of IllinoisDr. Hans Crombag 252 Engineering Research University of Leyden ...Laboratory Education Research Center 103 South Mathews Street Boerhaavelaan 2 Urbana, IL 61801 2334 EN Leyden The NETHERLANDS V.- University of Illinois...Naval Air Station Pensacola, FL 32508 Ms. Kathleen Moreno Navy Personnel R&D Center Dr. Gary Marco Code 62 Stop 31-E San Diego, CA 92152 Educational

  20. An appraisal of undergraduate curriculum of technical education in ...

    African Journals Online (AJOL)

    The purpose of this study was to appraise the curriculum of technical teacher education in terms of its compatibility to the goals of the programme. A sample of three Universities offering technical teacher programme was used for the study. Components of the technical teacher education curriculum in each institution were ...

  1. Process of technical performance: essential features and their economic view

    OpenAIRE

    Zhylinska, O.

    2010-01-01

    Essential features of technical performance have been defined in the context of similarity of its components such as research and development, training of technical/engineering personnel and providing technical services. Also peculiarities of economic view have been examined in terms of information model of managing.

  2. Flexible time domain averaging technique

    Science.gov (United States)

    Zhao, Ming; Lin, Jing; Lei, Yaguo; Wang, Xiufeng

    2013-09-01

    Time domain averaging(TDA) is essentially a comb filter, it cannot extract the specified harmonics which may be caused by some faults, such as gear eccentric. Meanwhile, TDA always suffers from period cutting error(PCE) to different extent. Several improved TDA methods have been proposed, however they cannot completely eliminate the waveform reconstruction error caused by PCE. In order to overcome the shortcomings of conventional methods, a flexible time domain averaging(FTDA) technique is established, which adapts to the analyzed signal through adjusting each harmonic of the comb filter. In this technique, the explicit form of FTDA is first constructed by frequency domain sampling. Subsequently, chirp Z-transform(CZT) is employed in the algorithm of FTDA, which can improve the calculating efficiency significantly. Since the signal is reconstructed in the continuous time domain, there is no PCE in the FTDA. To validate the effectiveness of FTDA in the signal de-noising, interpolation and harmonic reconstruction, a simulated multi-components periodic signal that corrupted by noise is processed by FTDA. The simulation results show that the FTDA is capable of recovering the periodic components from the background noise effectively. Moreover, it can improve the signal-to-noise ratio by 7.9 dB compared with conventional ones. Experiments are also carried out on gearbox test rigs with chipped tooth and eccentricity gear, respectively. It is shown that the FTDA can identify the direction and severity of the eccentricity gear, and further enhances the amplitudes of impulses by 35%. The proposed technique not only solves the problem of PCE, but also provides a useful tool for the fault symptom extraction of rotating machinery.

  3. An EarthCube Roadmap for Cross-Domain Interoperability in the Geosciences: Governance Aspects

    Science.gov (United States)

    Zaslavsky, I.; Couch, A.; Richard, S. M.; Valentine, D. W.; Stocks, K.; Murphy, P.; Lehnert, K. A.

    2012-12-01

    The goal of cross-domain interoperability is to enable reuse of data and models outside the original context in which these data and models are collected and used and to facilitate analysis and modeling of physical processes that are not confined to disciplinary or jurisdictional boundaries. A new research initiative of the U.S. National Science Foundation, called EarthCube, is developing a roadmap to address challenges of interoperability in the earth sciences and create a blueprint for community-guided cyberinfrastructure accessible to a broad range of geoscience researchers and students. Infrastructure readiness for cross-domain interoperability encompasses the capabilities that need to be in place for such secondary or derivative-use of information to be both scientifically sound and technically feasible. In this initial assessment we consider the following four basic infrastructure components that need to be present to enable cross-domain interoperability in the geosciences: metadata catalogs (at the appropriate community defined granularity) that provide standard discovery services over datasets, data access services, models and other resources of the domain; vocabularies that support unambiguous interpretation of domain resources and metadata; services used to access data repositories and other resources including models, visualizations and workflows; and formal information models that define structure and semantics of the information returned on service requests. General standards for these components have been proposed; they form the backbone of large scale integration activities in the geosciences. By utilizing these standards, EarthCube research designs can take advantage of data discovery across disciplines using the commonality in key data characteristics related to shared models of spatial features, time measurements, and observations. Data can be discovered via federated catalogs and linked nomenclatures from neighboring domains, while standard data

  4. The impact of fatigue on the non-technical skills performance of critical care air ambulance clinicians.

    Science.gov (United States)

    Myers, J A; Powell, D M C; Aldington, S; Sim, D; Psirides, A; Hathaway, K; Haney, M F

    2017-11-01

    The relationship between fatigue-related risk and impaired clinical performance is not entirely clear. Non-technical factors represent an important component of clinical performance and may be sensitive to the effects of fatigue. The hypothesis was that the sum score of overall non-technical performance is degraded by fatigue. Nineteen physicians undertook two different simulated air ambulance missions, once when rested, and once when fatigued (randomised crossover design). Trained assessors blinded to participants' fatigue status performed detailed structured assessments based on expected behaviours in four non-technical skills domains: teamwork, situational awareness, task management, and decision making. Participants also provided self-ratings of their performance. The primary endpoint was the sum score of overall non-technical performance. The main finding, the overall non-technical skills performance rating of the clinicians, was better in rested than fatigued states (mean difference with 95% CI, 2.8 [2.2-3.4]). The findings remained consistent across individual non-technical skills domains; also when controlling for an order effect and examining the impact of a number of possible covariates. There was no difference in self-ratings of clinical performance between rested and fatigued states. Non-technical performance of critical care air transfer clinicians is degraded when they are fatigued. Fatigued clinicians may fail to recognise the degree to which their performance is compromised. These findings represent risk to clinical care quality and patient safety in the dynamic and isolated environment of air ambulance transfer. © 2017 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  5. 2017 Emerging Technology Domains Risk Survey

    Science.gov (United States)

    2017-10-01

    REV-03.18.2016.0 2017 Emerging Technology Domains Risk Survey Daniel Klinedinst Joel Land Kyle O’Meara October 2017 TECHNICAL REPORT CMU/SEI...Distribution Statement A: Approved for Public Release. Distribution is Unlimited. List of Tables Table 1: New and Emerging Technologies 2 Table 2: Security...Impact of New and Emerging Technologies 4 Table 3: Severity Classifications and Impact Scores 5 CMU/SEI-2017-TR-008 | SOFTWARE ENGINEERING

  6. Component reliability for electronic systems

    CERN Document Server

    Bajenescu, Titu-Marius I

    2010-01-01

    The main reason for the premature breakdown of today's electronic products (computers, cars, tools, appliances, etc.) is the failure of the components used to build these products. Today professionals are looking for effective ways to minimize the degradation of electronic components to help ensure longer-lasting, more technically sound products and systems. This practical book offers engineers specific guidance on how to design more reliable components and build more reliable electronic systems. Professionals learn how to optimize a virtual component prototype, accurately monitor product reliability during the entire production process, and add the burn-in and selection procedures that are the most appropriate for the intended applications. Moreover, the book helps system designers ensure that all components are correctly applied, margins are adequate, wear-out failure modes are prevented during the expected duration of life, and system interfaces cannot lead to failure.

  7. Progress report : Technical Physics Division

    International Nuclear Information System (INIS)

    Gopalaraman, C.P.; Deshpande, R.Y.

    1978-01-01

    The research and development work carried out in the Technical Physics Division of the Bhabha Atomic Research Centre, Bombay, is reported. Some of the achievements are: (1) fabrication of mass spectrometers for heavy water analysis and lithium 6/7 isotope ratio measurement, (2) fabrication of electronic components for mass spectrometers, (3) growing of sodium iodide crystals for radiation detectors, (4) development of sandwich detectors comprising of NaI(Tl) and CaI(Na), (5) fabrication of mass spectrometer type leak detectors and (6) fabrication of the high vacuum components of the vacuum system of the variable energy cyclotron based at Calcutta. (M.G.B.)

  8. Strategy of technical innovation

    International Nuclear Information System (INIS)

    Lee, Ga Jong

    1990-12-01

    This book deals with policy of scientific technique and technical innovation such as research for development and types of technical innovation, historical development and process of technical innovation, economic growth, technology change and investment for research and development, structure and form of technical transfer with the meaning process, from, structure and theory, economic growth and investment of research and development with experiential analysis and case study on strategy of technical innovation in electron and fine chemical industry.

  9. Technical Training Seminar

    CERN Multimedia

    2003-01-01

    Thursday 4 September From 14:00 to 17:00 - Training Centre Auditorium bldg. 593, room 11 The Summit Design VisualElite 4.0 Release Jean Marie St Paul / SUMMIT DESIGN, Europe, Technical Manager Michel Delcroix / SUMMIT DESIGN, Southern Europe, Sales F-95015 CERGY PONTOISE, France Summit Design is an important EDA digital hardware design tool supplier, and the industry leader in the emerging Electronic System Level design domain. Its VisualElite program has been used at CERN for several years. This seminar will include the highlights of the program's latest release. It will be illustrated how Summit Design products can provide a high-level C/C++ and SystemC functional modelling design and verification environment, enabling engineers to analyse system concepts before the implementation stage. The seminar will show how mixed SystemC and HDL simulation can be done, along with solutions for hardware/software development. • HDL new features: Connectivity Table Editor. Xemacs full integration. New NCsim ...

  10. Technical Training Seminar

    CERN Multimedia

    2003-01-01

    Thursday 4 September From 14:00 to 17:00 - Training Centre Auditorium bldg. 593, room 11 The Summit Design VisualElite 4.0 Release Jean Marie St Paul / SUMMIT DESIGN, Europe, Technical Manager Michel Delcroix / SUMMIT DESIGN, Southern Europe, Sales F-95015 CERGY PONTOISE, France Summit Design is an important EDA digital hardware design tool supplier, and the industry leader in the emerging Electronic System Level design domain. Its VisualElite program has been used at CERN for several years. This seminar will include the highlights of the program's latest release. It will be illustrated how Summit Design products can provide a high-level C/C++ and SystemC functional modelling design and verification environment, enabling engineers to analyse system concepts before the implementation stage. The seminar will show how mixed SystemC and HDL simulation can be done, along with solutions for hardware/software development. • HDL new features: Connectivity Table Editor. Xemacs full integration. New NCsi...

  11. A review and evaluation of the Langley Research Center's Scientific and Technical Information Program: Results of phase 6: The technical report. A survey and analysis

    Science.gov (United States)

    Mccullough, R. A.; Pinelli, T. E.; Pilley, D. D.; Stohrer, F. F.

    1982-01-01

    Current practice and usage using selected technical reports; literature relative to the sequential, language, and presentation components of technical reports; and NASA technical report publications standards are discussed. The effctiveness of the technical report as a product for information dissemination is considered.

  12. Supersymmetric domain walls

    NARCIS (Netherlands)

    Bergshoeff, Eric A.; Kleinschmidt, Axel; Riccioni, Fabio

    2012-01-01

    We classify the half-supersymmetric "domain walls," i.e., branes of codimension one, in toroidally compactified IIA/IIB string theory and show to which gauged supergravity theory each of these domain walls belong. We use as input the requirement of supersymmetric Wess-Zumino terms, the properties of

  13. Full waveform inversion in the frequency domain using classified time-domain residual wavefields

    Science.gov (United States)

    Son, Woohyun; Koo, Nam-Hyung; Kim, Byoung-Yeop; Lee, Ho-Young; Joo, Yonghwan

    2017-04-01

    We perform the acoustic full waveform inversion in the frequency domain using residual wavefields that have been separated in the time domain. We sort the residual wavefields in the time domain according to the order of absolute amplitudes. Then, the residual wavefields are separated into several groups in the time domain. To analyze the characteristics of the residual wavefields, we compare the residual wavefields of conventional method with those of our residual separation method. From the residual analysis, the amplitude spectrum obtained from the trace before separation appears to have little energy at the lower frequency bands. However, the amplitude spectrum obtained from our strategy is regularized by the separation process, which means that the low-frequency components are emphasized. Therefore, our method helps to emphasize low-frequency components of residual wavefields. Then, we generate the frequency-domain residual wavefields by taking the Fourier transform of the separated time-domain residual wavefields. With these wavefields, we perform the gradient-based full waveform inversion in the frequency domain using back-propagation technique. Through a comparison of gradient directions, we confirm that our separation method can better describe the sub-salt image than the conventional approach. The proposed method is tested on the SEG/EAGE salt-dome model. The inversion results show that our algorithm is better than the conventional gradient based waveform inversion in the frequency domain, especially for deeper parts of the velocity model.

  14. Evolutionary dynamics of protein domain architecture in plants

    Directory of Open Access Journals (Sweden)

    Zhang Xue-Cheng

    2012-01-01

    Full Text Available Abstract Background Protein domains are the structural, functional and evolutionary units of the protein. Protein domain architectures are the linear arrangements of domain(s in individual proteins. Although the evolutionary history of protein domain architecture has been extensively studied in microorganisms, the evolutionary dynamics of domain architecture in the plant kingdom remains largely undefined. To address this question, we analyzed the lineage-based protein domain architecture content in 14 completed green plant genomes. Results Our analyses show that all 14 plant genomes maintain similar distributions of species-specific, single-domain, and multi-domain architectures. Approximately 65% of plant domain architectures are universally present in all plant lineages, while the remaining architectures are lineage-specific. Clear examples are seen of both the loss and gain of specific protein architectures in higher plants. There has been a dynamic, lineage-wise expansion of domain architectures during plant evolution. The data suggest that this expansion can be largely explained by changes in nuclear ploidy resulting from rounds of whole genome duplications. Indeed, there has been a decrease in the number of unique domain architectures when the genomes were normalized into a presumed ancestral genome that has not undergone whole genome duplications. Conclusions Our data show the conservation of universal domain architectures in all available plant genomes, indicating the presence of an evolutionarily conserved, core set of protein components. However, the occurrence of lineage-specific domain architectures indicates that domain architecture diversity has been maintained beyond these core components in plant genomes. Although several features of genome-wide domain architecture content are conserved in plants, the data clearly demonstrate lineage-wise, progressive changes and expansions of individual protein domain architectures, reinforcing

  15. Components of laboratory accreditation.

    Science.gov (United States)

    Royal, P D

    1995-12-01

    Accreditation or certification is a recognition given to an operation or product that has been evaluated against a standard; be it regulatory or voluntary. The purpose of accreditation is to provide the consumer with a level of confidence in the quality of operation (process) and the product of an organization. Environmental Protection Agency/OCM has proposed the development of an accreditation program under National Environmental Laboratory Accreditation Program for Good Laboratory Practice (GLP) laboratories as a supplement to the current program. This proposal was the result of the Inspector General Office reports that identified weaknesses in the current operation. Several accreditation programs can be evaluated and common components identified when proposing a structure for accrediting a GLP system. An understanding of these components is useful in building that structure. Internationally accepted accreditation programs provide a template for building a U.S. GLP accreditation program. This presentation will discuss the traditional structure of accreditation as presented in the Organization of Economic Cooperative Development/GLP program, ISO-9000 Accreditation and ISO/IEC Guide 25 Standard, and the Canadian Association for Environmental Analytical Laboratories, which has a biological component. Most accreditation programs are managed by a recognized third party, either privately or with government oversight. Common components often include a formal review of required credentials to evaluate organizational structure, a site visit to evaluate the facility, and a performance evaluation to assess technical competence. Laboratory performance is measured against written standards and scored. A formal report is then sent to the laboratory indicating accreditation status. Usually, there is a scheduled reevaluation built into the program. Fee structures vary considerably and will need to be examined closely when building a GLP program.

  16. Measuring the global domain name system

    NARCIS (Netherlands)

    Casalicchio, E.; Shen, Xuemin; Caselli, M.; Coletta, A.

    2013-01-01

    The Internet is a worldwide distributed critical infrastructure, and it is composed of many vital components. While IP routing is the most important service, today the Domain Name System can be classified as the second most important, and has been defined as a critical infrastructure as well. DNS

  17. Assessment of technical risks

    Energy Technology Data Exchange (ETDEWEB)

    Jaeger, T A [Bundesanstalt fuer Materialpruefung, Berlin (Germany, F.R.)

    1978-01-01

    The safety of technical systems is so difficult to assess because the concept 'risk' contains technical-scientific factors as well as components of individual and social psychology. Immediate or short-term hazards of human life as i.e. caused by the operation of industrial plants and mediate and thus long-term hazards have to be distinguished. Characteristic for the second hazard groups is the great time-lag before the effect takes place. Thus a causal relationship can be recognized only late and not definitely. Even when the causes have been obviated the effects still show. The development of a systems-analytical model as a basis of decisive processes for the introduction of highly endangered large-scale technologies seems particularly difficult. A starting point for the quantification of the risk can still be seen in the product of the probability of realization and the extent of the damage. Public opinion, however, does not base its evaluations on an objective concept of risk but tends to have an attitude of aversion against great and disastrous accidents. On the other hand, plenty of slight accidents are accepted much more easily, even when the amount of deadly victims from accidents reaches dimensions beyond those of the rare large-scale accidents. Here, mostly the damage possible but not the probability of its occurence is seen, let alone the general use of the new technology. The value of the mathematical models for estimating risks is mainly due to the fact that they are able to clear up decisions.

  18. Shaking table testing of mechanical components

    International Nuclear Information System (INIS)

    Jurukovski, D.; Taskov, Lj.; Mamucevski, D.; Petrovski, D.

    1995-01-01

    Presented is the experience of the Institute of Earthquake Engineering and Engineering Seismology, Skopje, Republic of Macedonia in seismic qualification of mechanical components by shaking table testing. Technical data and characteristics for the three shaking tables available at the Institute are given. Also, for characteristic mechanical components tested at the Institute laboratories, basic data such as producer, testing investor, description of the component, testing regulation, testing equipment and final user of the results. (author)

  19. Developing a Domain Model for Relay Circuits

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth

    2009-01-01

    In this paper we stepwise develop a domain model for relay circuits as used in railway control systems. First we provide an abstract, property-oriented model of networks consisting of components that can be glued together with connectors. This model is strongly inspired by a network model...... for railways madeby Bjørner et.al., however our model is more general: the components can be of any kind and can later be refined to e.g. railway components or circuit components. Then we show how the abstract network model can be refined into an explicit model for relay circuits. The circuit model describes...... the statics as well as the dynamics of relay circuits, i.e. how a relay circuit can be composed legally from electrical components as well as how the components may change state over time. Finally the circuit model is transformed into an executable model, and we show how a concrete circuit can be defined...

  20. How to be an Effective Technical Writer?

    Directory of Open Access Journals (Sweden)

    M Solaiman Ali

    2012-07-01

    Full Text Available Abstract--This paper has focused on technical writing as a skill for engineers. It has sought to define technical writing and throw light on the content and technique of writing the various components of successful technical reports (for example, articles, papers, or research reports, such as theses and dissertations. Then, it has highlighted other special features and principles of effective technical writing. The material in this paper is divided into seven major parts. Part 1 (Technical writing for engineers stresses that a successful engineering career requires strong writing skills. Part 2 (How to write the major sections or elements of a report describes the techniques of writing the abstract, introduction, literature review, procedure/methods & materials, results, discussion, conclusion, and recommendations. Part 3 (Special features of technical writing brings into focus some of the special features of technical writing such as tables & graphs in the text, graphics in instructions, team writing, ethics (plagiarism, document sources, three citation styles and IEEE reference style. Part 4 (Technical usage deals with writing abbreviations, initialisms and acronyms, numbers, units of measurement, and equations.Part 5 (Technical style highlights the imperative writing style and other features of technical writing such as the use of active and passive voices, plain vs. complex syntax, avoiding redundant or superfluous expressions, and vague generalities, using words or expressions with visual impact, the past tense to describe experimental work, the present tense to describe hypotheses, principles, theories and truths, and breaking up the text of the report into short sections. Part 6 (Document specifications emphasizes the technical writer’s need to conform to such document specifications as word count, format, font, number of words per line of text imposed. Part 7 (Reader-friendly technical writing suggests choosing the varied writing modes

  1. Technical Assistance Plan (TAP)

    Science.gov (United States)

    A Technical Assistance Plan (TAP) enables community groups to retain the services of an independent technical advisor and to provide resources for a community group to help inform other community members about site decisions.

  2. Technical report writing

    Science.gov (United States)

    Vidoli, Carol A.

    1992-01-01

    This manual covers the fundamentals of organizing, writing, and reviewing NASA technical reports. It was written to improve the writing skills of LeRC technical authors and the overall quality of their reports.

  3. Technical Report Writing Today

    DEFF Research Database (Denmark)

    Riordan, Daniel G.

    2014-01-01

    Section 1: Technical Communication Basics (8 chapters on tech com, audiences, tech com process, tech com style, researching, designing pages, using visual aids, describing). Section 2: Technical Communication Applications (7 chapters on sets of instructions, informal reports and email, developing...

  4. Technical training: places available

    CERN Document Server

    2013-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tel: 74924)

  5. Technical training - places available

    CERN Document Server

    2013-01-01

    If you would like more information on a course, or have any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tel: 74924)

  6. Technical training: places available

    CERN Multimedia

    2013-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tél : 74924)  

  7. VANDAL technical overview

    International Nuclear Information System (INIS)

    Unsworth, M.D.

    1989-07-01

    This document is concerned with the technicalities of the VANDAL code and covers the technical details of each of the systems modules in turn. Covered are SAMPLING, FLOW, VAULT, GEOSPHERE, BIOSPHERE and TIMESTEPPING. (author)

  8. Technical training: places available

    CERN Multimedia

    2014-01-01

    If you would like more information on a course, or have any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tel: 74924)

  9. Technical training: places available

    CERN Multimedia

    2014-01-01

    If you would like more information on a course, or have any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Marie Lahchimi, Technical Training Administration (Tel: 74924)

  10. Handbook of Technical Communication

    OpenAIRE

    Mehler , Alexander; Romary , Laurent; Gibbon , Dafydd

    2012-01-01

    International audience; The handbook "Technical Communication" brings together a variety of topics which range from the role of technical media in human communication to the linguistic, multimodal enhancement of present-day technologies. It covers the area of computer-mediated text, voice and multimedia communication as well as of technical documentation. In doing so, the handbook takes professional and private communication into account. Special emphasis is put on technical communication bas...

  11. The general technical regulation and the standardization

    International Nuclear Information System (INIS)

    Laverie, Michel; Houze, Christian; Lebouleux, Philippe

    1980-01-01

    Through a certain number of procedures, the thorough appreciation of the safety of a nuclear installation relies more on a specific appreciation taking into account the references as a whole, than on a technical regulation which claims to cover all the problems. Nevertheless, a French technical regulation structure regarding the safety domain must be built up progressively. The authors consider the principles of such a structure, and together they make the inventory of the works, finished, in progress or contemplated. The description of this specifically French approach emphazises the multiple and complementary forms given to statutory implements [fr

  12. Conserved Domain Database (CDD)

    Data.gov (United States)

    U.S. Department of Health & Human Services — CDD is a protein annotation resource that consists of a collection of well-annotated multiple sequence alignment models for ancient domains and full-length proteins.

  13. Magnetization reversal in ferromagnetic spirals via domain wall motion

    Science.gov (United States)

    Schumm, Ryan D.; Kunz, Andrew

    2016-11-01

    Domain wall dynamics have been investigated in a variety of ferromagnetic nanostructures for potential applications in logic, sensing, and recording. We present a combination of analytic and simulated results describing the reliable field driven motion of a domain wall through the arms of a ferromagnetic spiral nanowire. The spiral geometry is capable of taking advantage of the benefits of both straight and circular wires. Measurements of the in-plane components of the spirals' magnetization can be used to determine the angular location of the domain wall, impacting the magnetoresistive applications dependent on the domain wall location. The spirals' magnetization components are found to depend on the spiral parameters: the initial radius and spacing between spiral arms, along with the domain wall location. The magnetization is independent of the parameters of the rotating field used to move the domain wall, and therefore the model is valid for current induced domain wall motion as well. The speed of the domain wall is found to depend on the frequency of the rotating driving field, and the domain wall speeds can be reliably varied over several orders of magnitude. We further demonstrate a technique capable of injecting multiple domain walls and show the reliable and unidirectional motion of domain walls through the arms of the spiral.

  14. Components of the Profitability of Technical Currency Trading

    OpenAIRE

    Schulmeister, Stephan

    2005-01-01

    This paper investigates the sources of the profitability of 1024 moving average and momentum models when trading in the German mark (euro)/U.S. dollar market based on daily data. The main results are as follows. First, each of these models would have been profitable over the entire sample period. Second, this profitability is exclusively due to the exploitation of persistent exchange rate trends. Third, these results do not change substantially when trading is examined within subperiods. Four...

  15. Microgrid Design Toolkit (MDT) Technical Documentation and Component Summaries

    Energy Technology Data Exchange (ETDEWEB)

    Arguello, Bryan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Katherine A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Eddy, John P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    The Microgrid Design Toolkit (MDT) is a decision support software tool for microgrid designers to use during the microgrid design process. The models that support the two main capabilities in MDT are described. The first capability, the Microgrid Sizing Capability (MSC), is used to determine the size and composition of a new microgrid in the early stages of the design process. MSC is a mixed-integer linear program that is focused on developing a microgrid that is economically viable when connected to the grid. The second capability is focused on refining a microgrid design for operation in islanded mode. This second capability relies on two models: the Technology Management Optimization (TMO) model and Performance Reliability Model (PRM). TMO uses a genetic algorithm to create and refine a collection of candidate microgrid designs. It uses PRM, a simulation based reliability model, to assess the performance of these designs. TMO produces a collection of microgrid designs that perform well with respect to one or more performance metrics.

  16. Towards Domain-specific Flow-based Languages

    DEFF Research Database (Denmark)

    Zarrin, Bahram; Baumeister, Hubert; Sarjoughian, Hessam S.

    2018-01-01

    describe their problems and solutions, instead of using general purpose programming languages. The goal of these languages is to improve the productivity and efficiency of the development and simulation of concurrent scientific models and systems. Moreover, they help to expose parallelism and to specify...... the concurrency within a component or across different independent components. In this paper, we introduce the concept of domain-specific flowbased languages which allows domain experts to use flow-based languages adapted to a particular problem domain. Flow-based programming is used to support concurrency, while......Due to the significant growth of the demand for data-intensive computing, in addition to the emergence of new parallel and distributed computing technologies, scientists and domain experts are leveraging languages specialized for their problem domain, i.e., domain-specific languages, to help them...

  17. Center for Center for Technology for Advanced Scientific Component Software (TASCS)

    Energy Technology Data Exchange (ETDEWEB)

    Kostadin, Damevski [Virginia State Univ., Petersburg, VA (United States)

    2015-01-25

    A resounding success of the Scientific Discovery through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedented computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS)1 tackles these these issues by exploiting component-based software development to facilitate collaborative high-performance scientific computing.

  18. Center for Technology for Advanced Scientific Component Software (TASCS) Consolidated Progress Report July 2006 - March 2009

    Energy Technology Data Exchange (ETDEWEB)

    Bernholdt, D E; McInnes, L C; Govindaraju, M; Bramley, R; Epperly, T; Kohl, J A; Nieplocha, J; Armstrong, R; Shasharina, S; Sussman, A L; Sottile, M; Damevski, K

    2009-04-14

    A resounding success of the Scientific Discovery through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedented computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS) tackles these issues by exploiting component-based software development to facilitate collaborative high-performance scientific computing.

  19. Teaching Technical Writing - Towards Technical Writing

    DEFF Research Database (Denmark)

    Kastberg, Peter

    2000-01-01

    In this paper I will present key aspects of the curriculum for the university degree in technical translation that I have designed for and subsequently implemented at the German Department of the Aarhus School of Business, Denmark. My starting point will be a critical discussion of the norm that ...... of technical writing.......In this paper I will present key aspects of the curriculum for the university degree in technical translation that I have designed for and subsequently implemented at the German Department of the Aarhus School of Business, Denmark. My starting point will be a critical discussion of the norm...... that used to govern what the quality of an LSP text should be as opposed to the standpoint, which I advocate. By way of summing up, I will show how a university curriculum is designed so that - upon graduation - the technical translator could also be methodological quite well suited to take on the challenge...

  20. Technical rules in law

    Energy Technology Data Exchange (ETDEWEB)

    Debelius, J

    1978-08-01

    An important source of knowledge for technical experts is the state of the art reflected by catalogues of technical rules. Technical rules may also achieve importance in law due to a legal transformation standard. Here, rigid and flexible reference are controversial with regard to their admissibility from the point of view of constitutional law. In case of a divergence from the generally accepted technical rules, it is assumed - refutably - that the necessary care had not been taken. Technical rules are one out of several sources of information; they have no normative effect. This may result in a duty of anyone applying them to review the state of technology himself.

  1. Technical rules in law

    International Nuclear Information System (INIS)

    Debelius, J.

    1978-01-01

    An important source of knowledge for technical experts is the state of the art reflected by catalogues of technical rules. Technical rules may also achieve importance in law due to a legal transformation standard. Here, rigid and flexible reference are controversial with regard to their admissibility from the point of view of constitutional law. In case of a divergence from the generally accepted technical rules, it is assumed - refutably - that the necessary care had not been taken. Technical rules are one out of several sources of information; they have no normative effect. This may result in a duty of anyone applying them to review the state of technology himself. (orig.) [de

  2. Linac4 Technical Design Report

    CERN Document Server

    Arnaudon, L; Baylac, M; Bellodi, G; Body, Y; Borburgh, J; Bourquin, P; Broere, J; Brunner, O; Bruno, L; Carli, C; Caspers, Friedhelm; Cousineau, S M; Cuvet, Y; De Almeida Martins, C; Dobers, T; Fowler, T; Garoby, R; Gerigk, F; Goddard, B; Hanke, K; Hori, M; Jones, M; Kahle, K; Kalbreier, Willi; Kroyer, T; Küchler, D; Lombardi, A M; López-Hernandez, L A; Magistris, M; Martini, M; Maury, S; Page, E; Paoluzzi, M; Pasini, M; Raich, U; Rossi, C; Royer, J P; Sargsyan, E; Serrano, J; Scrivens, R; Silari, M; Timmins, M; Venturini-Delsolaro, W; Vretenar, M; Wegner, R; Weterings, W; Zickler, T

    2006-01-01

    Linac4 is an H- linear accelerator, intended to replace Linac2 as injector to the PS Booster (PSB). By delivering to the PSB a beam at 160 MeV energy, Linac4 will provide the conditions to double the brightness and intensity of the beam from the PSB, thus removing the first bottleneck towards higher brightness for the LHC and simplifying operation. Moreover, this new linac constitutes an essential component of any of the envisaged LHC upgrade scenarios and could open the way to future extensions of the CERN accelerator complex towards higher performance. This Technical Design Report presents a detailed technical overview of the Linac4 design as it stands at end 2006.

  3. FLAMMABLE GAS TECHNICAL BASIS DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    KRIPPS, L.J.

    2005-02-18

    This document describes the qualitative evaluation of frequency and consequences for double shell tank (DST) and single shell tank (SST) representative flammable gas accidents and associated hazardous conditions without controls. The evaluation indicated that safety-significant SSCs and/or TSRS were required to prevent or mitigate flammable gas accidents. Discussion on the resulting control decisions is included. This technical basis document was developed to support of the Tank Farms Documented Safety Analysis (DSA) and describes the risk binning process for the flammable gas representative accidents and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous condition based on an evaluation of the event frequency and consequence.

  4. Gravitational field of spherical domain wall in higher dimension

    Indian Academy of Sciences (India)

    An exact solution of Einstein's equations is found describing the gravitational field of a spherical domain wall with nonvanishing stress component in the direction perpendicular to the plane of the wall. Also we have studied the motion of test particle around the domain wall.

  5. Clojure for domain-specific languages

    CERN Document Server

    Kelker, Ryan D

    2013-01-01

    An example-oriented approach to develop custom domain-specific languages.If you've already developed a few Clojure applications and wish to expand your knowledge on Clojure or domain-specific languages in general, then this book is for you. If you're an absolute Clojure beginner, then you may only find the detailed examples of the core Clojure components of value. If you've developed DSLs in other languages, this Lisp and Java-based book might surprise you with the power of Clojure.

  6. DEPONTO: A Reusable Dependability Domain Ontology

    Directory of Open Access Journals (Sweden)

    Teodora Sanislav

    2015-08-01

    Full Text Available This paper proposes a dependability reusable ontology for knowledge representation. The fundamental knowledge related to dependability follows its taxonomy. Thus, this paper gives an analysis of what is the dependability domain ontology andof its components.The dependability domain ontology plays an important role in ensuring the dependability of information systems by providing support for their diagnosis in case of faults, errors and failures.The proposed ontology is used as a dependability framework in two case study Cyber-Physical Systemswhich demonstrate its reusability within this category of systems.

  7. Domain Engineering, A Software Engineering Discipline in Need of Research

    DEFF Research Database (Denmark)

    Bjørner, Dines

    2000-01-01

    . The aim of this paper is to advocate: that researchers study these development method components, and that universities focus their education on basing well-nigh any course on the use of formal techniques: Specification and verification, and that software engineers take heed: Start applying formal......, and these again seem more stable than software designs. Thus, almost like the universal laws of physics, it pays off to first develop theories of domains. But domain engineering, as in fact also requirements engineering, really is in need of thoroughly researched development principles, techniques and tools...... techniques. A brief example of describing stake-holder perspectives will be given - on the background of which we then proceed to survey the notions of domain intrinsics, domain support technologies, domain management & organisation, domain rules & regulations, domain human behaviour, etc. We show elsewhere...

  8. Functional interchangeability of late domains, late domain cofactors and ubiquitin in viral budding.

    Directory of Open Access Journals (Sweden)

    Maria Zhadina

    2010-10-01

    Full Text Available The membrane scission event that separates nascent enveloped virions from host cell membranes often requires the ESCRT pathway, which can be engaged through the action of peptide motifs, termed late (L- domains, in viral proteins. Viral PTAP and YPDL-like L-domains bind directly to the ESCRT-I and ALIX components of the ESCRT pathway, while PPxY motifs bind Nedd4-like, HECT-domain containing, ubiquitin ligases (e.g. WWP1. It has been unclear precisely how ubiquitin ligase recruitment ultimately leads to particle release. Here, using a lysine-free viral Gag protein derived from the prototypic foamy virus (PFV, where attachment of ubiquitin to Gag can be controlled, we show that several different HECT domains can replace the WWP1 HECT domain in chimeric ubiquitin ligases and drive budding. Moreover, artificial recruitment of isolated HECT domains to Gag is sufficient to stimulate budding. Conversely, the HECT domain becomes dispensable if the other domains of WWP1 are directly fused to an ESCRT-1 protein. In each case where budding is driven by a HECT domain, its catalytic activity is essential, but Gag ubiquitination is dispensable, suggesting that ubiquitin ligation to trans-acting proteins drives budding. Paradoxically, however, we also demonstrate that direct fusion of a ubiquitin moiety to the C-terminus of PFV Gag can also promote budding, suggesting that ubiquitination of Gag can substitute for ubiquitination of trans-acting proteins. Depletion of Tsg101 and ALIX inhibits budding that is dependent on ubiquitin that is fused to Gag, or ligated to trans-acting proteins through the action of a PPxY motif. These studies underscore the flexibility in the ways that the ESCRT pathway can be engaged, and suggest a model in which the identity of the protein to which ubiquitin is attached is not critical for subsequent recruitment of ubiquitin-binding components of the ESCRT pathway and viral budding to proceed.

  9. Technical approach to aging management

    International Nuclear Information System (INIS)

    Vora, J.P.; Johnson, A.B. Jr.; Allen, R.P.

    1992-10-01

    Systematic and effective control of age-related degradation of safety-related components, systems, and structures in nuclear power plants (NPPs) is an important challenge to plant operators. Several data bases, available to provide guidance on aging management, are summarized. However, the ultimate consideration is: How effectively is aging management being implemented at individual plants? Illustrated here is a specific strategy that served to develop the technical data base for the Nuclear Plant Aging Research Program. The strategy is comprehensive, systematic, and adaptable. Effective aging management at NPPs could be facilitated by a parallel strategy. The elements of a strategy are suggested

  10. Aspectos técnicos da cateterização do seio coronariano baseada no componente atrial do eletrograma intracavitário e anatomia radiológica durante o procedimento de implante de marcapasso biventricular Technical aspects of coronary sinus catheterization based on the atrial component of the intracavitary electrogram and radiological anatomy during the implantation procedure of a biventricular pacemaker

    Directory of Open Access Journals (Sweden)

    Fernando Sérgio Oliva de Souza

    2006-04-01

    Full Text Available OBJETIVO: Apresentar uma proposição técnica baseada na experiência de 130 implantes utilizando técnica simplificada para cateterização do seio coronariano, baseada no componente atrial do eletrograma intracavi-tário e anatomia radiológica. MÉTODOS: De outubro de 2001 a outubro de 2004 foram realiza-dos 130 implantes de marcapasso biventricular, utilizando-se anatomia radiológica e observação de eletrograma intracavitário, com prioridade ao componente atrial. RESULTADOS: O implante do sistema, utilizando-se a estimulação do ventrículo esquerdo via seio coronariano, não foi possível em 8 pacientes. Em 12 pacientes foram observadas dificuldades na canulação do óstio coronário e em 15 pacientes observaram-se dificuldades de progressão do eletrodo através do seio coronariano. O tempo médio de utilização de radioscopia foi de 18,69 min. CONCLUSÃO: A técnica de implante, utilizando a morfologia do componente atrial do eletrograma intracavitário e anatomia radiológica, demonstrou ser pouco trabalhosa, segura e eficaz para canulação do óstio do seio coronariano, necessitando de reduzido tempo de radioscopia.OBJECTIVE: To present a technical proposal based on the experience of 130 implantations using a simplified technique for coronary sinus catheterization, based on the atrial component of the intracavitary electrogram and radiological anatomy. METHODS: From October, 2001 to October, 2004, 130 biventricular pacemaker implantations were performed, using radiological anatomy and observation of the intracavitary electrogram, focusing on the atrial component. RESULTS: The implantation of the system using left ventricular pacing via coronary sinus was not possible in 8 patients. Difficulties on the cannulation of the coronary ostium were felt in 12 patients and difficulties of lead advancement through the coronary sinus were felt in 15 patients. The mean time of radioscopy utilization was 18.69 min. CONCLUSION: The

  11. Domain: Labour market

    NARCIS (Netherlands)

    Oude Mulders, J.; Wadensjö, E.; Hasselhorn, H.M.; Apt, W.

    This domain chapter is dedicated to summarize research on the effects of labour market contextual factors on labour market participation of older workers (aged 50+) and identify research gaps. While employment participation and the timing of (early) retirement is often modelled as an individual

  12. Cellulose binding domain proteins

    Science.gov (United States)

    Shoseyov, Oded; Shpiegl, Itai; Goldstein, Marc; Doi, Roy

    1998-01-01

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.

  13. Domain-Specific Multimodeling

    DEFF Research Database (Denmark)

    Hessellund, Anders

    the overall level of abstraction. It does, however, also introduce a new problem of coordinating multiple different languages in a single system. We call this problem the coordination problem. In this thesis, we present the coordination method for domain-specific multimodeling that explicitly targets...

  14. GlycoDomainViewer

    DEFF Research Database (Denmark)

    Joshi, Hiren J; Jørgensen, Anja; Schjoldager, Katrine T

    2018-01-01

    features, which enhances visibility and accessibility of the wealth of glycoproteomic data being generated. The GlycoDomainViewer enables visual exploration of glycoproteomic data, incorporating information from recent N- and O-glycoproteome studies on human and animal cell lines and some organs and body...

  15. Technical infrastructure monitoring from the CCC

    CERN Document Server

    Stowisek, J; Suwalska, A; CERN. Geneva. TS Department

    2005-01-01

    In the summer of 2005, the Technical Infrastructure Monitoring (TIM) system will replace the Technical Data Server (TDS) as the monitoring system of CERN’s technical services. Whereas the TDS was designed for the LEP, TIM will have to cope with the much more extensive monitoring needs of the LHC era. To cater for this, the new system has been built on industry-standard hardware and software components, using Java 2 Enterprise Edition (J2EE) technology to create a highly available, reliable, scalable and flexible control system. A first version of TIM providing the essential functionality will be deployed in the MCR in June 2005. Additional functionality and more sophisticated tools for system maintenance will be ready before the start-up of the LHC in 2007, when CERN’s technical infrastructure will be monitored from the future CERN Control Centre.

  16. Writing a technical note.

    Science.gov (United States)

    Ng, K H; Peh, W C G

    2010-02-01

    A technical note is a short article giving a brief description of a specific development, technique or procedure, or it may describe a modification of an existing technique, procedure or device applicable to medicine. The technique, procedure or device described should have practical value and should contribute to clinical diagnosis or management. It could also present a software tool, or an experimental or computational method. Technical notes are variously referred to as technical innovations or technical developments. The main criteria for publication will be the novelty of concepts involved, the validity of the technique and its potential for clinical applications.

  17. Technical Elements (CCT1)

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund; Wittchen, Kim Bjarne

    2017-01-01

    Many of the aspects dealt with in the CA EPBD are closely interlinked with each other and may refer to both new and existing buildings, as well as to inspection and certification. This is also true for technical aspects, such as the calculation methodologies, and how to include technical systems......’ efficiency or how to integrate renewable energy within them. The central team for Technical Elements deals with issues of a technical nature, which are common to new and existing buildings, and/or with minimum demands, certification and inspection. This report focuses on the implementation of Articles 3, 4...

  18. Vehicle Systems Analysis Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The mission of the Vehicle Systems Analysis Technical Team (VSATT) is to evaluate the performance and interactions of proposed advanced automotive powertrain components and subsystems, in a vehicle systems context, to inform ongoing research and development activities and maximize the potential for fuel efficiency improvements and emission reduction.

  19. The framing of scientific domains

    DEFF Research Database (Denmark)

    Dam Christensen, Hans

    2014-01-01

    domains, and UNISIST helps understanding this navigation. Design/methodology/approach The UNISIST models are tentatively applied to the domain of art history at three stages, respectively two modern, partially overlapping domains, as well as an outline of an art historical domain anno c1820...

  20. Chromatin domains and function

    NARCIS (Netherlands)

    Fransz, P.; Meier, I.

    2009-01-01

    The inheritance of biological traits involves not only the transfer of genetic information in the form of DNA, but also epigenetic information. The latter is encrypted in a DNA component, methylation of cytosine residues, and in non-DNA components such as histone modifications, non-histone proteins,

  1. OECD/NEA component operational experience, degradation and ageing project

    International Nuclear Information System (INIS)

    Gott, K.; Nevander, O.; Riznic, J.; Lydell, B.

    2015-01-01

    Several OECD Member Countries have agreed to establish the OECD/NEA 'Component Operational Experience, Degradation and Ageing Programme' (CODAP) to encourage multilateral co-operation in the collection and analysis of data relating to degradation and failure of metallic piping and non-piping metallic passive components in commercial nuclear power plants. The scope of the data collection includes service-induced wall thinning, part through-wall cracks, through-wall cracks with and without active leakage, and instances of significant degradation of metallic passive components, including piping pressure boundary integrity. CODAP is the continuation of the 2002-2011 'OECD/NEA Pipe Failure Data Exchange Project' (OPDE) and the Stress Corrosion Cracking Working Group of the 2006-2010 - OECD/NEA SCC and Cable Ageing project - (SCAP). OPDE was formally launched in May 2002. Upon completion of the 3. Term (May 2011), the OPDE project was officially closed to be succeeded by CODAP. In May 2011, 13 countries signed the CODAP first Term agreement. The first Term (2011-2014) work plan includes the development of a web-based relational event database on passive, metallic components in commercial nuclear power plants, a web-based knowledge base on material degradation, codes and standards relating to structural integrity and national practices for managing material degradation. The work plan also addresses the preparation of Topical Reports to foster technical cooperation and to deepen the understanding of national differences in ageing management. These Topical Reports are in the public domain and available for download on the NEA web site. Published in 2014, a first Topical Report addressed flow accelerated corrosion (FAC) of carbon steel and low alloy steel piping. A second Topical Report addresses operating experience with electro-hydraulic control (EHC) and instrument air (IA) system piping

  2. VGB-requirements regarding technical data for power plants

    International Nuclear Information System (INIS)

    Richnow, Joerg

    2009-01-01

    Much of the technical plant data resulting from the planning, construction and start-up of power plants is needed for subsequent management and maintenance. Because of this, VGB has taken the initiative and has defined standard minimum requirements from power plant operators for technical plant data. They relate to the details and structure of this data, the definition of material classes and characteristics for the main power plant components and IT implementation for delivery of the technical plant data. (orig.)

  3. RAMP 2005 technical report

    International Nuclear Information System (INIS)

    2006-01-01

    This technical report provided details of all monitoring activities conducted by the Regional Aquatics Monitoring Program (RAMP), which was initiated in 1997 to examine the impacts of oil sands mining development on aquatic systems in the region. RAMP's objective is to integrate aquatic monitoring activities in order to identify long-term trends and regional issues related to the environment in the Regional Municipality of Wood Buffalo. In 2005, RAMP focused on key components of boreal aquatic ecosystems. This report provided full outlines of all climate and hydrology monitoring activities; water and sedimentation analyses; and studies of benthic communities in rivers, lakes, and deltas. Sets of measurements endpoints were used to represent the health and integrity of valued environmental resources. Satellite imager was used to estimate activities related to oil sands developments. The report was divided into subsections which related monitoring activities for various rivers and tributaries in the region. Small and negligible calculated changes were observed in hydrologic conditions in the Athabasca River mainstem. No discernible changes in water and sediment quality were observed that could positively be ascribed to oil sands developments in the region. Very little evidence suggested that fish populations had changed as a result of increased activities in the region. The influence of oil sands development activities on the aquatic resources of the Athabasca River mainstem were minor and mostly undetectable. The results of fish tissue studies from the lower Athabasca River showed that concentrations of mercury in fish tissues occurred at levels that posed a high risk to subsistence fishers. A higher number of metal concentrations in some lakes in the region was attributed to natural causes. The results of a sentinel species monitoring program conducted at the Ells River watershed were also included. Recommendations for further refining RAMP programs were also

  4. Technical Training for Managers.

    Science.gov (United States)

    Haverland, Edgar M.

    The question has arisen as to what kind of information a manager without extensive technical training needs to learn to supervise effectively. For example, the Nike Hercules fire control platoon leader, usually an officer in his first active duty assignment, seldom has had extensive technical training. Yet he is responsibile for the…

  5. Technical Manual. The ACT®

    Science.gov (United States)

    ACT, Inc., 2014

    2014-01-01

    This manual contains technical information about the ACT® college readiness assessment. The principal purpose of this manual is to document the technical characteristics of the ACT in light of its intended purposes. ACT regularly conducts research as part of the ongoing formative evaluation of its programs. The research is intended to ensure that…

  6. Developing Technical Skill Assessments

    Science.gov (United States)

    Hyslop, Alisha

    2009-01-01

    One of the biggest challenges facing the career and technical education (CTE) community as it works to implement the 2006 Perkins Act is responding to more rigorous requirements for reporting on CTE students' technical skill attainment. The U.S. Department of Education suggested in non-regulatory guidance that states and locals use the number of…

  7. Transformation of technical infrastructure

    DEFF Research Database (Denmark)

    Nielsen, Susanne Balslev

    1998-01-01

    article about the need of new planning forums in order to initiate transformations with in management of large technical systems for energy, waste and water supply.......article about the need of new planning forums in order to initiate transformations with in management of large technical systems for energy, waste and water supply....

  8. Technical Writing Tips

    Science.gov (United States)

    Kennedy, Patrick M.

    2004-01-01

    The main reason engineers, technicians, and programmers write poor technical documents is because they have had little training or experience in that area. This article addresses some of the basics that students can use to master technical writing tasks. The article covers the most common problems writers make and offers suggestions for improving…

  9. Research in Technical Colleges

    Science.gov (United States)

    MacLennan, A.

    2008-01-01

    Purpose: The purpose of this paper is to list and demonstrate areas in which research needs to be carried out, or questions answered, in order to raise the quality of technical education. Design/methodology/approach: The area of technical education expanded very rapidly in the late 1950s, and there was little comprehensive knowledge regarding the…

  10. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Glasser, Alan H. [Fusion Theory and Computation Inc., Kingston, WA (United States)

    2018-02-02

    Final technical report on DE-SC0016106. This is the final technical report for a portion of the multi-institutional CEMM project. This report is centered around 3 publications and a seminar presentation, which have been submitted to E-Link.

  11. Financial Statement Audit Report of Guilford Technical Community College.

    Science.gov (United States)

    Campbell, Ralph

    This report presents the results of the Guilford Technical Community College financial statement audit for the fiscal year ending on June 30, 1998. Guilford Technical Community College is a component of the State of North Carolina, thus the authority to audit is granted by Article 5A of G.S. 147. The accounts and operations of the institution were…

  12. Collaborating for Success: Team Teaching the Engineering Technical Thesis

    Science.gov (United States)

    Keating, Terrence; Long, Mike

    2012-01-01

    This paper will examine the collaborative teaching process undertaken at College of the North Atlantic-Qatar (CNA-Q) by Engineering and the Communication faculties to improve the overall quality of engineering students' capstone projects known as the Technical Thesis. The Technical Thesis is divided into two separate components: a proposal stage…

  13. The Agency's technical co-operation activities in 1993

    International Nuclear Information System (INIS)

    1994-08-01

    This document reviews the IAEA's Technical Cooperation activities for 1993. Apart from an overview, the report contains reviews by Agency programmes and technical divisions, by area, by component and by fund. Summaries of project implementation are also included, as well as indications of the achievements of projects completed in 1993

  14. Technical guidelines for environmental dredging of contaminated sediments

    Science.gov (United States)

    2008-09-01

    This report provides technical guidelines for evaluating : environmental dredging as a sediment remedy component. This document : supports the Contaminated Sediment Remediation Guidance for : Hazardous Waste Sites, released by the U.S. Environmental ...

  15. Organisation, Quality and Challenges in the B. Ed Technical ...

    African Journals Online (AJOL)

    Technical) degree programme rated the organization and quality of the industrial attachment component of the programme. Challenges students faced during industrial attachment were also examined. A case study design was used. Twenty-five final ...

  16. Technical Agency in Practice

    DEFF Research Database (Denmark)

    Krummheuer, Antonia Lina

    2015-01-01

    ) description of hybrid networks in which human and non-human actants are granted agency without differentiating different kinds of agency, EMCA focuses on the member's perspectives and the situated construction of technical agency that is made relevant within an ongoing interaction. Based on an EMCA analysis......The paper combines the discussion of technical agency and hybrid networks of Actor-Network Theory (ANT) with an ethnomethodological/conversation analytical (EMCA) perspective on situated practices in which participants ascribe agency to technical artefacts. While ANT works with (ethnographic...... of three video recordings of situations in which technical agency is made relevant by the human participants, the paper demonstrates different ways in which agency is granted to technical artefacts. Human participants can treat a technology as communication partner, as an active part (and actant...

  17. TENCompetence Domain Model

    NARCIS (Netherlands)

    2006-01-01

    This is the version 1.1 of the TENCompetence Domain Model (version 1.0 released at 19-6-2006; version 1.1 at 9-11-2008). It contains several files: a) a pdf with the model description, b) three jpg files with class models (also in the pdf), c) a MagicDraw zip file with the model itself, d) a release

  18. Human research ethics committees in technical universities.

    Science.gov (United States)

    Koepsell, David; Brinkman, Willem-Paul; Pont, Sylvia

    2014-07-01

    Human research ethics has developed in both theory and practice mostly from experiences in medical research. Human participants, however, are used in a much broader range of research than ethics committees oversee, including both basic and applied research at technical universities. Although mandated in the United States, the United Kingdom, Canada, and Australia, non-medical research involving humans need not receive ethics review in much of Europe, Asia, Latin America, and Africa. Our survey of the top 50 technical universities in the world shows that, where not specifically mandated by law, most technical universities do not employ ethics committees to review human studies. As the domains of basic and applied sciences expand, ethics committees are increasingly needed to guide and oversee all such research regardless of legal requirements. We offer as examples, from our experience as an ethics committee in a major European technical university, ways in which such a committee provides needed services and can help ensure more ethical studies involving humans outside the standard medical context. We provide some arguments for creating such committees, and in our supplemental article, we provide specific examples of cases and concerns that may confront technical, engineering, and design research, as well as outline the general framework we have used in creating our committee. © The Author(s) 2014.

  19. SH2 Domain Histochemistry.

    Science.gov (United States)

    Buhs, Sophia; Nollau, Peter

    2017-01-01

    Among posttranslational modifications, the phosphorylation of tyrosine residues is a key modification in cell signaling. Because of its biological importance, characterization of the cellular state of tyrosine phosphorylation is of great interest. Based on the unique properties of endogenously expressed SH2 domains recognizing tyrosine phosphorylated signaling proteins with high specificity we have developed an alternative approach, coined SH2 profiling, enabling us to decipher complex patterns of tyrosine phosphorylation in various normal and cancerous tissues. So far, SH2 profiling has largely been applied for the analysis of protein extracts with the limitation that information on spatial distribution and intensity of tyrosine phosphorylation within a tissue is lost. Here, we describe a novel SH2 domain based strategy for differential characterization of the state of tyrosine phosphorylation in formaldehyde-fixed and paraffin-embedded tissues. This approach demonstrates that SH2 domains may serve as very valuable tools for the analysis of the differential state of tyrosine phosphorylation in primary tissues fixed and processed under conditions frequently applied by routine pathology laboratories.

  20. Pump Component Model in SPACE Code

    International Nuclear Information System (INIS)

    Kim, Byoung Jae; Kim, Kyoung Doo

    2010-08-01

    This technical report describes the pump component model in SPACE code. A literature survey was made on pump models in existing system codes. The models embedded in SPACE code were examined to check the confliction with intellectual proprietary rights. Design specifications, computer coding implementation, and test results are included in this report

  1. The DIMA web resource--exploring the protein domain network.

    Science.gov (United States)

    Pagel, Philipp; Oesterheld, Matthias; Stümpflen, Volker; Frishman, Dmitrij

    2006-04-15

    Conserved domains represent essential building blocks of most known proteins. Owing to their role as modular components carrying out specific functions they form a network based both on functional relations and direct physical interactions. We have previously shown that domain interaction networks provide substantially novel information with respect to networks built on full-length protein chains. In this work we present a comprehensive web resource for exploring the Domain Interaction MAp (DIMA), interactively. The tool aims at integration of multiple data sources and prediction techniques, two of which have been implemented so far: domain phylogenetic profiling and experimentally demonstrated domain contacts from known three-dimensional structures. A powerful yet simple user interface enables the user to compute, visualize, navigate and download domain networks based on specific search criteria. http://mips.gsf.de/genre/proj/dima

  2. Cylinder components properties, applications, materials

    CERN Document Server

    2016-01-01

    Owing to the ever-increasing requirements to be met by gasoline and diesel engines in terms of CO2 reduction, emission behavior, weight, and service life, a comprehensive understanding of combustion engine components is essential today. It is no longer possible for professionals in automotive engineering to manage without the corresponding expertise, whether they work in the field of design, development, testing, or maintenance. This technical book provides in-depth answers to questions about design, production, and machining of cylinder components. In this second edition, every section has been revised and expanded to include the latest developments in the combustion engine. Content Piston rings Piston pins and piston pin circlips Bearings Connecting rods Crankcase and cylinder liners Target audience Engineers in the field of engine development and maintenanceLecturers and students in the areas of mechanical engineering, engine technology, and vehicle constructionAnyone interested in technology Publisher MAH...

  3. Higher-order assemblies of BAR domain proteins for shaping membranes.

    Science.gov (United States)

    Suetsugu, Shiro

    2016-06-01

    Most cellular organelles contain lipid bilayer membranes. The earliest characterization of cellular organelles was performed by electron microscopy observation of such membranes. However, the precise mechanisms for shaping the membrane in particular subcellular organelles is poorly understood. Classically, the overall cellular shape, i.e. the shape of the plasma membrane, was thought to be governed by the reorganization of cytoskeletal components such as actin and microtubules. The plasma membrane contains various submicron structures such as clathrin-coated pits, caveolae, filopodia and lamellipodia. These subcellular structures are either invaginations or protrusions and are associated with the cytoskeleton. Therefore, it could be hypothesized that there are membrane-binding proteins that cooperates with cytoskeleton in shaping of plasma membrane organelles. Proteins with the Bin-Amphiphysin-Rvs (BAR) domain connect a variety of membrane shapes to actin filaments. The BAR domains themselves bend the membranes by their rigidity and then mold the membranes into tubules through their assembly as spiral polymers, which are thought to be involved in the various submicron structures. Membrane tubulation by polymeric assembly of the BAR domains is supposed to be regulated by binding proteins, binding lipids and the mechanical properties of the membrane. This review gives an overview of BAR protein assembly, describes the significance of the assembly and discusses how to study the assembly in the context of membrane and cellular morphology. The technical problems encountered in microscopic observation of BAR domain assembly are also discussed. © The Author 2016. Published by Oxford University Press on behalf of The Japanese Society of Microscopy. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. Domain decomposition method for solving elliptic problems in unbounded domains

    International Nuclear Information System (INIS)

    Khoromskij, B.N.; Mazurkevich, G.E.; Zhidkov, E.P.

    1991-01-01

    Computational aspects of the box domain decomposition (DD) method for solving boundary value problems in an unbounded domain are discussed. A new variant of the DD-method for elliptic problems in unbounded domains is suggested. It is based on the partitioning of an unbounded domain adapted to the given asymptotic decay of an unknown function at infinity. The comparison of computational expenditures is given for boundary integral method and the suggested DD-algorithm. 29 refs.; 2 figs.; 2 tabs

  5. Assessing readiness of cyberinfrastructure resources for cross-domain interoperability: a view from an NSF EarthCube roadmap

    Science.gov (United States)

    Zaslavsky, Ilya; Couch, Alva; Richard, Stephen; Valentine, David; Lehnert, Kerstin; Stocks, Karen; Murphy, Philip

    2013-04-01

    EarthCube is a new research initiative of the U.S. National Science Foundation, with the mission to develop community-guided cyberinfrastructure integrating data, models and other resources across geoscience disciplines. Analysis and modeling of physical processes that are not confined to disciplinary or jurisdictional boundaries, requires that data and models can be re-used outside the original context in which they are collected or developed. Infrastructure readiness for cross-domain interoperability encompasses the capabilities that need to be in place to enable such information re-use and ensure that it is both scientifically sound and technically feasible. In an ideal cross-domain information integration scenario, resources can be discovered via federated catalogs and linked nomenclatures from neighboring domains, while standard data services can be used to transparently compile composite data products and to integrate information using commonality in key data characteristics related to shared models of spatial features, time measurements, and observations. The main premise of the cross-domain readiness assessment is that when accessing domain resources from another domain, a user expects to be able to discover these resources, interpret them, retrieve the information, and integrate it with other data. Documentation of the resource must be sufficient for a user in a different context to determine fitness for use, and establish trust in scientific soundness. As part of an EarthCube roadmap focused on cross-domain interoperability, we explored a number of approaches to cyberinfrastructure readiness assessment, addressing both readiness of existing resources, and readiness of processes that enable cross-domain communication and information exchange across disciplinary boundaries. Our initial assessment considers basic infrastructure components required to enable cross-domain interoperability in the geosciences. These components, and the evaluation metrics

  6. The dynamics of the asymmetric motion of domain walls of sandwich domain structure in a Fe-based amorphous ribbon

    Energy Technology Data Exchange (ETDEWEB)

    Zhmetko, D.N., E-mail: sergey.zhmetko@gmail.com [Department of Physics, Zaporizhzhya National University, 66 Zhukovsky Street, 69063 Zaporizhzhya (Ukraine); Zhmetko, S.D. [Department of Physics, Zaporizhzhya National University, 66 Zhukovsky Street, 69063 Zaporizhzhya (Ukraine); Troschenkov, Y.N. [Institute for Magnetism, 36-b Vernadsky Boulevard, 03142 Kyiv (Ukraine); Matsura, A.V. [Department of Physics, Zaporizhzhya National University, 66 Zhukovsky Street, 69063 Zaporizhzhya (Ukraine)

    2013-08-15

    The frequency dependence of asymmetry of the domain walls velocity relative to the middle plane of amorphous ribbon is investigated. An additional pressure of the same direction acting on each domain wall caused by dependence of eddy current damping on the coordinate of the domain wall is revealed. The microscopic mechanisms of this additional pressure are considered. - Highlights: ► Additional pressure on the domain wall, caused by inhomogeneity of its damping. ► Asymmetry of the coordinate of the nucleation of domain walls and their damping. ► Connection between the components of additional pressure and its direction. ► Interaction of domain walls with the surface defects of the amorphous ribbon.

  7. The dynamics of the asymmetric motion of domain walls of sandwich domain structure in a Fe-based amorphous ribbon

    International Nuclear Information System (INIS)

    Zhmetko, D.N.; Zhmetko, S.D.; Troschenkov, Y.N.; Matsura, A.V.

    2013-01-01

    The frequency dependence of asymmetry of the domain walls velocity relative to the middle plane of amorphous ribbon is investigated. An additional pressure of the same direction acting on each domain wall caused by dependence of eddy current damping on the coordinate of the domain wall is revealed. The microscopic mechanisms of this additional pressure are considered. - Highlights: ► Additional pressure on the domain wall, caused by inhomogeneity of its damping. ► Asymmetry of the coordinate of the nucleation of domain walls and their damping. ► Connection between the components of additional pressure and its direction. ► Interaction of domain walls with the surface defects of the amorphous ribbon

  8. Localization experience and future plan of NSLS primary components

    International Nuclear Information System (INIS)

    Kim, Haesoo

    1992-01-01

    Korea Heavy Industries and Construction Company is planning to obtain technical self-reliance of the component design, manufacturing and installation of the NSLS primary components as much as the target of 87% by 1995 as indicated in the technical self-reliance plan by the Korea Electric Power Company in 1988. In order to achieve this target, Koch has been involved in the component design, manufacturing and project management of the NSLS components from the early stage of the Young 3 and 4 project. In parallel, Koch has increased the self-reliance of the various fields taking full advantage of the technical documents, computer codes, training and consultation supplied by the technology transfer agreement. This paper presents the re-evaluation of the current status of technical self reliance as well as the make up plan to be implemented during the UCH 3 and 4 project for the area identified as the weakness

  9. Structural Characterization of Monomeric/Dimeric State of p59fyn SH2 Domain.

    Science.gov (United States)

    Huculeci, Radu; Kieken, Fabien; Garcia-Pino, Abel; Buts, Lieven; van Nuland, Nico; Lenaerts, Tom

    2017-01-01

    Src homology 2 (SH2) domains are key modulators in various signaling pathways allowing the recognition of phosphotyrosine sites of different proteins. Despite the fact that SH2 domains acquire their biological functions in a monomeric state, a multitude of reports have shown their tendency to dimerize. Here, we provide a technical description on how to isolate and characterize by gel filtration, circular dichroism (CD), and nuclear magnetic resonance (NMR) each conformational state of p59 fyn SH2 domain.

  10. Towards common technical standards

    International Nuclear Information System (INIS)

    Rahmat, H.; Suardi, A.R.

    1993-01-01

    In 1989, PETRONAS launched its Total Quality Management (TQM) program. In the same year the decision was taken by the PETRONAS Management to introduce common technical standards group wide. These standards apply to the design, construction, operation and maintenance of all PETRONAS installations in the upstream, downstream and petrochemical sectors. The introduction of common company standards is seen as part of an overall technical management system, which is an integral part of Total Quality Management. The Engineering and Safety Unit in the PETRONAS Central Office in Kuala Lumpur has been charged with the task of putting in place a set of technical standards throughout PETRONAS and its operating units

  11. A component architecture for the two-phase flows simulation system Neptune

    Energy Technology Data Exchange (ETDEWEB)

    Bechaud, C; Boucker, M; Douce, A [Electricite de France (EDF-RD/MFTT), 78 - Chatou (France); Grandotto, M [CEA Cadarache (DEN/DTP/STH), 13 - Saint-Paul-lez-Durance (France); Tajchman, M [CEA Saclay (DEN/DM2S/SFME), 91 - Gif-sur-Yvette (France)

    2003-07-01

    Electricite de France (EdF) and the French atomic energy commission (Cea) have planed a large project to build a new set of software in nuclear reactors analysis. One of the main idea is to allow coupled calculations in which several scientific domains are involved. This paper presents the software architecture of the two-phase flows simulation Neptune project. Neptune should allow computations of two-phase flows in 3 dimensions under normal operating conditions as well as safety conditions. Three scales are identified: the local scale where there is only homogenization between the two phases, an intermediate scale where solid internal structures are homogenized with the fluid and the system scale where some parts of the geometry under study are considered point-wise or subject to one dimensional simplifications. The main properties of this architecture are as follow: -) coupling with scientific domains, and between different scales, -) re-using of quite all or parts of existing validated codes, -) components usable by the different scales, -) easy introducing of new physical modeling as well as new numerical methods, -) local, distributed and parallel computing. The Neptune architecture is based on the component concept with stable and well suited interface. In the case of a distributed application the components are managed through a Corba bus. The building of the components is organized in shell: a programming shell (Fortran or C++ routines), a managing shell (C++ language), an interpreted shell (Python language), a Corba shell and a global driving shell (C++ or Python). Neptune will use the facilities offered by the Salome project: pre and post processors and controls. A data model has been built to have a common access to the information exchanged between the components (meshes, fields, physical and technical information). This architecture has first been setup and tested on some simple but significant cases and is now currently in use to build the Neptune

  12. A component architecture for the two-phase flows simulation system Neptune

    International Nuclear Information System (INIS)

    Bechaud, C.; Boucker, M.; Douce, A.; Grandotto, M.; Tajchman, M.

    2003-01-01

    Electricite de France (EdF) and the French atomic energy commission (Cea) have planed a large project to build a new set of software in nuclear reactors analysis. One of the main idea is to allow coupled calculations in which several scientific domains are involved. This paper presents the software architecture of the two-phase flows simulation Neptune project. Neptune should allow computations of two-phase flows in 3 dimensions under normal operating conditions as well as safety conditions. Three scales are identified: the local scale where there is only homogenization between the two phases, an intermediate scale where solid internal structures are homogenized with the fluid and the system scale where some parts of the geometry under study are considered point-wise or subject to one dimensional simplifications. The main properties of this architecture are as follow: -) coupling with scientific domains, and between different scales, -) re-using of quite all or parts of existing validated codes, -) components usable by the different scales, -) easy introducing of new physical modeling as well as new numerical methods, -) local, distributed and parallel computing. The Neptune architecture is based on the component concept with stable and well suited interface. In the case of a distributed application the components are managed through a Corba bus. The building of the components is organized in shell: a programming shell (Fortran or C++ routines), a managing shell (C++ language), an interpreted shell (Python language), a Corba shell and a global driving shell (C++ or Python). Neptune will use the facilities offered by the Salome project: pre and post processors and controls. A data model has been built to have a common access to the information exchanged between the components (meshes, fields, physical and technical information). This architecture has first been setup and tested on some simple but significant cases and is now currently in use to build the Neptune

  13. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Aristos Aristidou Natureworks); Robert Kean (NatureWorks); Tom Schechinger (IronHorse Farms, Mat); Stuart Birrell (Iowa State); Jill Euken (Wallace Foundation & Iowa State)

    2007-10-01

    The two main objectives of this project were: 1) to develop and test technologies to harvest, transport, store, and separate corn stover to supply a clean raw material to the bioproducts industry, and 2) engineer fermentation systems to meet performance targets for lactic acid and ethanol manufacturers. Significant progress was made in testing methods to harvest corn stover in a “single pass” harvest mode (collect corn grain and stover at the same time). This is technically feasible on small scale, but additional equipment refinements will be needed to facilitate cost effective harvest on a larger scale. Transportation models were developed, which indicate that at a corn stover yield of 2.8 tons/acre and purchase price of $35/ton stover, it would be unprofitable to transport stover more than about 25 miles; thus suggesting the development of many regional collection centers. Therefore, collection centers should be located within about 30 miles of the farm, to keep transportation costs to an acceptable level. These collection centers could then potentially do some preprocessing (to fractionate or increase bulk density) and/or ship the biomass by rail or barge to the final customers. Wet storage of stover via ensilage was tested, but no clear economic advantages were evident. Wet storage eliminates fire risk, but increases the complexity of component separation and may result in a small loss of carbohydrate content (fermentation potential). A study of possible supplier-producer relationships, concluded that a “quasi-vertical” integration model would be best suited for new bioproducts industries based on stover. In this model, the relationship would involve a multiyear supply contract (processor with purchase guarantees, producer group with supply guarantees). Price will likely be fixed or calculated based on some formula (possibly a cost plus). Initial quality requirements will be specified (but subject to refinement).Producers would invest in harvest

  14. Book Review: New Perspectives on Technical Editing

    Science.gov (United States)

    Murphy, A. J. (Ed.); Sterken, Christiaan

    2012-08-01

    New Perspectives on Technical Editing by Avon J. Murphy (ed.) ISBN : 978-0895033949 (2010) Baywood Publishing Company Inc, Hardcover, 210 pages, 35.5 GBP This book presents a collection of 10 chapters dealing with diverse aspects of technical editing (ie, editorial planning, and analysis and structural changes made to other people's technological documents): research in technical editing, trends and teaching of technical editing, copyediting, and technical journal editing. The role and function of the modern journal and book editor is also dealt with in detail. Each chapter is written by an expert in the field: senior editors, university professors in technical communication, technical writers and linguists. The ever-evolving role of the editor is clearly elucidated in several historical reviews, and in the descriptions of the expectations for the future. A very striking aspect of this book is its extensive collection of bibliographic resources: every chapter lists dozens of very useful references, and the closing chapter, and annotated bibliography, contain many not so well known references, and are most useful. All in all, the book is a treasure trove listing more than 400 references, in addition to numerous webpage URLs embedded in the texts. The book is designed to help the reader to understand current practices and norms in technical editing, and to help to take action in editing as well as in teaching and educating would-be editors. The audience for this book thus includes editors and teachers, but also writers, researchers and students. A deep reading of this book will result in a better understanding of the difference between full technical editing and its much narrower component so well known as copyediting, and will convince any prospective editor that editing should not be undertaken if the people involved do not master the art of precision and accuracy in technical (as well as in human) communication, do not possess the technical know how and computer

  15. Component-Level Prognostics Health Management Framework for Passive Components - Advanced Reactor Technology Milestone: M2AT-15PN2301043

    Energy Technology Data Exchange (ETDEWEB)

    Ramuhalli, Pradeep; Roy, Surajit; Hirt, Evelyn H.; Prowant, Matthew S.; Pitman, Stan G.; Tucker, Joseph C.; Dib, Gerges; Pardini, Allan F.

    2015-06-19

    This report describes research results to date in support of the integration and demonstration of diagnostics technologies for prototypical advanced reactor passive components (to establish condition indices for monitoring) with model-based prognostics methods. Achieving this objective will necessitate addressing several of the research gaps and technical needs described in previous technical reports in this series.

  16. Frequency domain analysis of piping systems under short duration loading

    International Nuclear Information System (INIS)

    Sachs, K.; Sand, H.; Lockau, J.

    1981-01-01

    In piping analysis two procedures are used almost exclusively: the modal superposition method for relatively long input time histories (e.g., earthquake) and direct integration of the equations of motion for short input time histories. A third possibility, frequency domain analysis, has only rarely been applied to piping systems to date. This paper suggests the use of frequency domain analysis for specific piping problems for which only direct integration could be used in the past. Direct integration and frequency domain analysis are compared, and it is shown that the frequency domain method is less costly if more than four or five load cases are considered. In addition, this method offers technical advantages, such as more accurate representation of modal damping and greater insight into the structural behavior of the system. (orig.)

  17. Functional Domain Driven Design

    OpenAIRE

    Herrera Guzmán, Sergio

    2016-01-01

    Las tecnologías están en constante expansión y evolución, diseñando nuevas técnicas para cumplir con su fin. En el desarrollo de software, las herramientas y pautas para la elaboración de productos software constituyen una pieza en constante evolución, necesarias para la toma de decisiones sobre los proyectos a realizar. Uno de los arquetipos para el desarrollo de software es el denominado Domain Driven Design, donde es importante conocer ampliamente el negocio que se desea modelar en form...

  18. Feature-level domain adaptation

    DEFF Research Database (Denmark)

    Kouw, Wouter M.; Van Der Maaten, Laurens J P; Krijthe, Jesse H.

    2016-01-01

    -level domain adaptation (flda), that models the dependence between the two domains by means of a feature-level transfer model that is trained to describe the transfer from source to target domain. Subsequently, we train a domain-adapted classifier by minimizing the expected loss under the resulting transfer...... modeled via a dropout distribution, which allows the classiffier to adapt to differences in the marginal probability of features in the source and the target domain. Our experiments on several real-world problems show that flda performs on par with state-of-the-art domainadaptation techniques.......Domain adaptation is the supervised learning setting in which the training and test data are sampled from different distributions: training data is sampled from a source domain, whilst test data is sampled from a target domain. This paper proposes and studies an approach, called feature...

  19. Compensating for Incomplete Domain Knowledge

    National Research Council Canada - National Science Library

    Scott, Lynn M; Drezner, Steve; Rue, Rachel; Reyes, Jesse

    2007-01-01

    .... First, many senior leader positions require experience in more than one functional or operational domain, but it is difficult to develop a corps of senior leaders with all the required combinations of domain knowledge...

  20. Technical standards in nuclear area

    International Nuclear Information System (INIS)

    Grimberg, M.

    1978-01-01

    The technical standardization in nuclear area is discussed. Also, the competence of CNEN in standardization pursuit is analysed. Moreover, the process of working up of technical standards is explained; in addition, some kinds of technical standards are discussed. (author) [pt

  1. Research regarding reverse engineering for aircraft components

    Directory of Open Access Journals (Sweden)

    Udroiu Razvan

    2017-01-01

    Full Text Available Reverse engineering is a useful technique used in manufacturing and design process of new components. In aerospace industry new components can be developed, based on existing components without technical Computer Aided Design (CAD data, in order to reduce the development cycle of new products. This paper proposes a methodology wherein the CAD model of turbine blade can be build using computer aided reverse engineering technique utilising a 5 axis Coordinate Measuring Machine (CMM. The proposed methodology uses a scanning strategy by features, followed by a design methodology for 3D modelling of complex shapes.

  2. SAM Technical Contacts

    Science.gov (United States)

    These technical contacts are available to help with questions regarding method deviations, modifications, sample problems or interferences, quality control requirements, the use of alternative methods, or the need to address analytes or sample types.

  3. INDOT Technical Training Plan

    Science.gov (United States)

    2012-04-01

    The study provides the background documents necessary for the development of a Technical Training Plan and makes recommendations : for the content and structure of such a plan for the District Operations, Operations, Capital Program Management, and E...

  4. social & technical innovations

    International Development Research Centre (IDRC) Digital Library (Canada)

    CHANGE: GAPS BRIDGED BY SMART SOLUTIONS. CHALLENGE: INABILITY TO REACH THOSE IN NEED. SOLAR PANELS. OVERCOME POWER. SUPPLY CHALLENGES. IN BURKINA FASO. SOCIAL & TECHNICAL. INNOVATIONS. BANGLADESH BURKINA FASO ETHIOPIA KENYA LEBANON PERU VIETNAM.

  5. Superfund Technical Assistance Grants

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes data related to the Superfund Technical Assistance Grant program, including grant number, award amounts, award dates, period of performance,...

  6. OSH technical reference manual

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    In an evaluation of the Department of Energy (DOE) Occupational Safety and Health programs for government-owned contractor-operated (GOCO) activities, the Department of Labor`s Occupational Safety and Health Administration (OSHA) recommended a technical information exchange program. The intent was to share written safety and health programs, plans, training manuals, and materials within the entire DOE community. The OSH Technical Reference (OTR) helps support the secretary`s response to the OSHA finding by providing a one-stop resource and referral for technical information that relates to safe operations and practice. It also serves as a technical information exchange tool to reference DOE-wide materials pertinent to specific safety topics and, with some modification, as a training aid. The OTR bridges the gap between general safety documents and very specific requirements documents. It is tailored to the DOE community and incorporates DOE field experience.

  7. NCDC Technical Reports

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NCDC Technical Reports is a set of retrospective analyses produced by the Research Customer Service Group and the National Climatic Data Center from 1995 to 2008....

  8. Socio-technical Betwixtness

    DEFF Research Database (Denmark)

    Bossen, Claus

    2017-01-01

    the intrinsically social and technical interwovenness of design, and the necessity of including affected people and stakeholders in the design process. This betwixtness of socio-technical design is demonstrated by the analysis of two IT systems for healthcare: a foundational model for electronic healthcare records......This chapter focusses on two challenges for socio-technical design: Having to choose between different rationales for design, and the adequate understanding and depiction of the work to be redesigned. These two challenges betwixt the otherwise strong tenets of socio-technical design of pointing out......, and an IT system organizing hospital porters’ work. The conceptual background for the analysis of the cases is provided by a short introduction to different rationales for organizational design, and by pointing to the differences between a linear, rationalistic versus an interactional depiction of work....

  9. Technical report writing today

    CERN Document Server

    Riordan, Daniel G

    2014-01-01

    "Technical Report Writing Today" provides thorough coverage of technical writing basics, techniques, and applications. Through a practical focus with varied examples and exercises, students internalize the skills necessary to produce clear and effective documents and reports. Project worksheets help students organize their thoughts and prepare for assignments, and focus boxes highlight key information and recent developments in technical communication. Extensive individual and collaborative exercises expose students to different kinds of technical writing problems and solutions. Annotated student examples - more than 100 in all - illustrate different writing styles and approaches to problems. Numerous short and long examples throughout the text demonstrate solutions for handling writing assignments in current career situations. The four-color artwork in the chapter on creating visuals keeps pace with contemporary workplace capabilities. The Tenth Edition offers the latest information on using electronic resum...

  10. The technical supervision interface

    CERN Document Server

    Sollander, P

    1998-01-01

    The Technical Control Room (TCR) is currently using 30 different applications for the remote supervision of the technical infrastructure at CERN. These applications have all been developed with the CERN made Uniform Man Machine Interface (UMMI) tools built in 1990. However, the visualization technology has evolved phenomenally since 1990, the Technical Data Server (TDS) has radically changed our control system architecture, and the standardization and the maintenance of the UMMI applications have become important issues as their number increases. The Technical Supervision Interface is intended to replace the UMMI and solve the above problems. Using a standard WWW-browser for the display, it will be inherently multi-platform and hence available for control room operators, equipment specialists and on-call personnel.

  11. Ligand binding by PDZ domains

    DEFF Research Database (Denmark)

    Chi, Celestine N.; Bach, Anders; Strømgaard, Kristian

    2012-01-01

    , for example, are particularly rich in these domains. The general function of PDZ domains is to bring proteins together within the appropriate cellular compartment, thereby facilitating scaffolding, signaling, and trafficking events. The many functions of PDZ domains under normal physiological as well...... as pathological conditions have been reviewed recently. In this review, we focus on the molecular details of how PDZ domains bind their protein ligands and their potential as drug targets in this context....

  12. Summarization by domain ontology navigation

    DEFF Research Database (Denmark)

    Andreasen, Troels; Bulskov, Henrik

    2013-01-01

    of the subject. In between these two extremes, conceptual summaries encompass selected concepts derived using background knowledge. We address in this paper an approach where conceptual summaries are provided through a conceptualization as given by an ontology. The ontology guiding the summarization can...... be a simple taxonomy or a generative domain ontology. A domain ontology can be provided by a preanalysis of a domain corpus and can be used to condense improved summaries that better reflects the conceptualization of a given domain....

  13. Towards a Conceptual Design of a Cross-Domain Integrative Information System for the Geosciences

    Science.gov (United States)

    Zaslavsky, I.; Richard, S. M.; Valentine, D. W.; Malik, T.; Gupta, A.

    2013-12-01

    As geoscientists increasingly focus on studying processes that span multiple research domains, there is an increased need for cross-domain interoperability solutions that can scale to the entire geosciences, bridging information and knowledge systems, models, software tools, as well as connecting researchers and organization. Creating a community-driven cyberinfrastructure (CI) to address the grand challenges of integrative Earth science research and education is the focus of EarthCube, a new research initiative of the U.S. National Science Foundation. We are approaching EarthCube design as a complex socio-technical system of systems, in which communication between various domain subsystems, people and organizations enables more comprehensive, data-intensive research designs and knowledge sharing. In particular, we focus on integrating 'traditional' layered CI components - including information sources, catalogs, vocabularies, services, analysis and modeling tools - with CI components supporting scholarly communication, self-organization and social networking (e.g. research profiles, Q&A systems, annotations), in a manner that follows and enhances existing patterns of data, information and knowledge exchange within and across geoscience domains. We describe an initial architecture design focused on enabling the CI to (a) provide an environment for scientifically sound information and software discovery and reuse; (b) evolve by factoring in the impact of maturing movements like linked data, 'big data', and social collaborations, as well as experience from work on large information systems in other domains; (c) handle the ever increasing volume, complexity and diversity of geoscience information; (d) incorporate new information and analytical requirements, tools, and techniques, and emerging types of earth observations and models; (e) accommodate different ideas and approaches to research and data stewardship; (f) be responsive to the existing and anticipated needs

  14. The development of component-based information systems

    CERN Document Server

    Cesare, Sergio de; Macredie, Robert

    2015-01-01

    This work provides a comprehensive overview of research and practical issues relating to component-based development information systems (CBIS). Spanning the organizational, developmental, and technical aspects of the subject, the original research included here provides fresh insights into successful CBIS technology and application. Part I covers component-based development methodologies and system architectures. Part II analyzes different aspects of managing component-based development. Part III investigates component-based development versus commercial off-the-shelf products (COTS), includi

  15. Socio-Technical Security Metrics (Dagstuhl Seminar 14491)

    NARCIS (Netherlands)

    Gollmann, Dieter; Herley, Cormac; Koenig, Vincent; Pieters, Wolter; Sasse, Martina Angela

    2015-01-01

    This report documents the program and the outcomes of Dagstuhl Seminar 14491 "Socio-Technical Security Metrics". In the domain of safety, metrics inform many decisions, from the height of new dikes to the design of nuclear plants. We can state, for example, that the dikes should be high enough to

  16. Expansion of protein domain repeats.

    Directory of Open Access Journals (Sweden)

    Asa K Björklund

    2006-08-01

    Full Text Available Many proteins, especially in eukaryotes, contain tandem repeats of several domains from the same family. These repeats have a variety of binding properties and are involved in protein-protein interactions as well as binding to other ligands such as DNA and RNA. The rapid expansion of protein domain repeats is assumed to have evolved through internal tandem duplications. However, the exact mechanisms behind these tandem duplications are not well-understood. Here, we have studied the evolution, function, protein structure, gene structure, and phylogenetic distribution of domain repeats. For this purpose we have assigned Pfam-A domain families to 24 proteomes with more sensitive domain assignments in the repeat regions. These assignments confirmed previous findings that eukaryotes, and in particular vertebrates, contain a much higher fraction of proteins with repeats compared with prokaryotes. The internal sequence similarity in each protein revealed that the domain repeats are often expanded through duplications of several domains at a time, while the duplication of one domain is less common. Many of the repeats appear to have been duplicated in the middle of the repeat region. This is in strong contrast to the evolution of other proteins that mainly works through additions of single domains at either terminus. Further, we found that some domain families show distinct duplication patterns, e.g., nebulin domains have mainly been expanded with a unit of seven domains at a time, while duplications of other domain families involve varying numbers of domains. Finally, no common mechanism for the expansion of all repeats could be detected. We found that the duplication patterns show no dependence on the size of the domains. Further, repeat expansion in some families can possibly be explained by shuffling of exons. However, exon shuffling could not have created all repeats.

  17. A probabilistic model for component-based shape synthesis

    KAUST Repository

    Kalogerakis, Evangelos; Chaudhuri, Siddhartha; Koller, Daphne; Koltun, Vladlen

    2012-01-01

    represents probabilistic relationships between properties of shape components, and relates them to learned underlying causes of structural variability within the domain. These causes are treated as latent variables, leading to a compact representation

  18. Training for Technical Assistants: Technical Assistance Program

    Science.gov (United States)

    1986-09-01

    shortage of technical ptfesson until such time as English , "speking instructors might be trained, There. would be An aumcation of committed on-calI...12 hours in classroom Instruction, students in English as a Second nel Research and Development Computer.taught students Language. The program Is...hbeels "p.-ogram. A Iot ’ atar boiler arn tank heats týe food enroute to its destination. 1.0. A new tor of dust ptectleon to protect machine .perators

  19. TECHNICAL BASIS DOCUMENT FOR NATURAL EVENT HAZARDS

    International Nuclear Information System (INIS)

    KRIPPS, L.J.

    2006-01-01

    This technical basis document was developed to support the documented safety analysis (DSA) and describes the risk binning process and the technical basis for assigning risk bins for natural event hazard (NEH)-initiated accidents. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous conditions based on an evaluation of the frequency and consequence. Note that the risk binning process is not applied to facility workers, because all facility worker hazardous conditions are considered for safety-significant SSCs and/or TSR-level controls

  20. Technical basis document for natural event hazards

    International Nuclear Information System (INIS)

    CARSON, D.M.

    2003-01-01

    This technical basis document was developed to support the Tank Farms Documented Safety Analysis (DSA), and describes the risk binning process and the technical basis for assigning risk bins for natural event hazards (NEH)-initiated representative accident and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous conditions based on an evaluation of the frequency and consequence. Note that the risk binning process is not applied to facility workers, because all facility worker hazardous conditions are considered for safety-significant SSCs and/or TSR-level controls. Determination of the need for safety-class SSCs was performed in accordance with DOE-STD-3009-94, ''Preparation Guide for US Department of Energy Nonreactor Nuclear Facility Documented Safety Analyses'', as described in this report

  1. Technical specifications and performance of CANDU fuel

    International Nuclear Information System (INIS)

    Sejnoha, R.

    1997-01-01

    The relations between Technical Specifications and fuel performance are discussed in terms of design limits and margins. The excellent performance record of CANDU reactor fuel demonstrates that the fuel design defined in the Technical Specifications (and with it other components of the procurement cycle, such as fuel manufacturing), satisfy the requirements. New requirements, changing conditions of fuel application and accumulating experience make periodic updates of the Technical Specifications necessary. Under the CANDU Owners Group (COG) Working Party 9, a Work Package has been conducted to support the review of the Specifications and the documentation of the rationales for their requirements. So far, the review has been completed for 4 Specifications: 1 for Zircaloy tubing, and 3 for uranium dioxide powder. It is planned to complete the review of all 11 currently used specifications by 1999. The paper summarizes the results achieved to mid 1997. (author)

  2. 78 FR 27963 - Reliability Technical Conference; Notice of Technical Conference

    Science.gov (United States)

    2013-05-13

    ... Technical Conference; Notice of Technical Conference Take notice that the Federal Energy Regulatory Commission will hold a Technical Conference on Tuesday, July 9, 2013 from 9:00 a.m. to 5:00 p.m. This... technical support for webcasts and offers the option of listening to the meeting via phone-bridge for a fee...

  3. 76 FR 64083 - Reliability Technical Conference; Notice of Technical Conference

    Science.gov (United States)

    2011-10-17

    ... Technical Conference; Notice of Technical Conference Take notice that the Federal Energy Regulatory Commission will hold a Technical Conference on Tuesday, November 29, 2011, from 1 p.m. to 5 p.m. and... reliability that were identified in earlier Commission technical conferences. The conference also will discuss...

  4. First experience with the new .cern Top Level Domain

    Science.gov (United States)

    Alvarez, E.; Malo de Molina, M.; Salwerowicz, M.; Silva De Sousa, B.; Smith, T.; Wagner, A.

    2017-10-01

    In October 2015, CERN’s core website has been moved to a new address, http://home.cern, marking the launch of the brand new top-level domain .cern. In combination with a formal governance and registration policy, the IT infrastructure needed to be extended to accommodate the hosting of Web sites in this new top level domain. We will present the technical implementation in the framework of the CERN Web Services that allows to provide virtual hosting, a reverse proxy solution and that also includes the provisioning of SSL server certificates for secure communications.

  5. Superphenix: technical and scientific achievements

    International Nuclear Information System (INIS)

    Guidez, Joel; Prele, Gerard

    2016-04-01

    In this book, the authors propose a synthesis of technical and scientific achievements related to the design, fabrication and eleven-year operation of Superphenix, the most powerful fast breeder reactor ever built and operated. They had the opportunity to use various and important archives maintained by the different involved institutions, actors and companies, such as the CEA with its MADONA database, AREVA and EDF. They address all the different fields: construction, chemistry, exploitation, handling, small and large components, materials, fuel manufacturing, environmental assessment, thermal hydraulics, the sodium-water reaction, sodium fires, the release of residual power, in-service inspection, and dismantling operations. Moreover, a chapter addresses design studies for Superphenix 2 and for the European Fast Reactor (EFR) which should be the successors of Superphenix

  6. Technical specifications requirements: Automated reasoning applications

    International Nuclear Information System (INIS)

    Lidsky, L.M.; Dobrzeniecki, A.B.

    1990-03-01

    Several software systems were developed and tested to determine what advantages could be gained from explicitly translating complicated regulatory requirements into computerized relationships. The Technical Specifications for US nuclear power plants were chosen as the test-bed application domain, and two analysis systems were developed to monitor plant compliance with operational limits, and track and schedule equipment test and maintenance activities mandated by Technical Specifications. Choosing PROLOG as the computer language to represent these regulatory requirements resulted in a natural match between the semantic structure of the written specifications and the corollary coded rules. Additional research results affirmed the utility of declarative programming styles, explicit management of problem complexity, and attention to the robustness and flexibility of the overall software systems. 5 refs., 2 figs

  7. Time Domain Induced Polarization

    DEFF Research Database (Denmark)

    Fiandaca, Gianluca; Auken, Esben; Christiansen, Anders Vest

    2012-01-01

    Time-domain-induced polarization has significantly broadened its field of reference during the last decade, from mineral exploration to environmental geophysics, e.g., for clay and peat identification and landfill characterization. Though, insufficient modeling tools have hitherto limited the use...... of time-domaininduced polarization for wider purposes. For these reasons, a new forward code and inversion algorithm have been developed using the full-time decay of the induced polarization response, together with an accurate description of the transmitter waveform and of the receiver transfer function......, to reconstruct the distribution of the Cole-Cole parameters of the earth. The accurate modeling of the transmitter waveform had a strong influence on the forward response, and we showed that the difference between a solution using a step response and a solution using the accurate modeling often is above 100...

  8. Domain architecture conservation in orthologs

    Science.gov (United States)

    2011-01-01

    Background As orthologous proteins are expected to retain function more often than other homologs, they are often used for functional annotation transfer between species. However, ortholog identification methods do not take into account changes in domain architecture, which are likely to modify a protein's function. By domain architecture we refer to the sequential arrangement of domains along a protein sequence. To assess the level of domain architecture conservation among orthologs, we carried out a large-scale study of such events between human and 40 other species spanning the entire evolutionary range. We designed a score to measure domain architecture similarity and used it to analyze differences in domain architecture conservation between orthologs and paralogs relative to the conservation of primary sequence. We also statistically characterized the extents of different types of domain swapping events across pairs of orthologs and paralogs. Results The analysis shows that orthologs exhibit greater domain architecture conservation than paralogous homologs, even when differences in average sequence divergence are compensated for, for homologs that have diverged beyond a certain threshold. We interpret this as an indication of a stronger selective pressure on orthologs than paralogs to retain the domain architecture required for the proteins to perform a specific function. In general, orthologs as well as the closest paralogous homologs have very similar domain architectures, even at large evolutionary separation. The most common domain architecture changes observed in both ortholog and paralog pairs involved insertion/deletion of new domains, while domain shuffling and segment duplication/deletion were very infrequent. Conclusions On the whole, our results support the hypothesis that function conservation between orthologs demands higher domain architecture conservation than other types of homologs, relative to primary sequence conservation. This supports the

  9. Mitigating component performance variation

    Science.gov (United States)

    Gara, Alan G.; Sylvester, Steve S.; Eastep, Jonathan M.; Nagappan, Ramkumar; Cantalupo, Christopher M.

    2018-01-09

    Apparatus and methods may provide for characterizing a plurality of similar components of a distributed computing system based on a maximum safe operation level associated with each component and storing characterization data in a database and allocating non-uniform power to each similar component based at least in part on the characterization data in the database to substantially equalize performance of the components.

  10. Comparação entre diferentes métodos de análise do componente lento do consumo de oxigênio: uma abordagem no domínio muito intenso de exercício Comparison between different methods of analysis of slow component of oxygen uptake: a view in severe exercise domain

    Directory of Open Access Journals (Sweden)

    Marcos G. Santana

    2007-08-01

    Full Text Available O objetivo do presente estudo foi comparar, em domínio muito intenso de exercício, diferentes técnicas utilizadas para medir a amplitude do componente lento (CL da cinética do consumo de oxigênio. Dez ciclistas treinados, do gênero masculino [média ± DP (idade: 25 ± 3,6 anos, massa corporal: 67,2 ± 4,5kg, altura: 174,8 ± 6,5cm e VO2max: 62,4 ± 3,1ml.kg¹.min¹], realizaram duas idênticas transições de carga constante (intensidade de 75%delta: 75% da diferença entre o VO2 no limiar de lactato e o VO2max em dias diferentes. O CL foi calculado a partir de diferentes métodos: (1 modelo biexponencial [VO2(t = VO2base + A1 (1 e-(t-TA1/t1 + A2 (1 e(tTA2/t2], (2 intervalos predeterminados (o deltaVO26-2: diferença do VO2 entre o segundo e o sexto minuto de exercício e o deltaVO263: diferença do VO2 entre o terceiro e o sexto minuto de exercício e (3 diferença entre o VO2 obtido no final do exercício e o valor obtido a partir de um ajuste monoexponencial do "componente primário" (tempo predeterminado de 120s (CL6"CP". Todos os métodos foram comparados entre si. Os resultados demonstraram significante subestimação do CL obtido pelo método de intervalos predeterminados (deltaVO26-2: 432 ± 126ml.min¹ e deltaVO263: 279 ± 88ml.min¹ quando comparado com o modelo biexponencial (676 ± 136ml.min¹ e ao CL6"CP" [(719 ± 265ml.min¹ (p The objective of the present study was to compare in severe exercise domain, different techniques used for measuring the amplitude of the slow component (SC of oxygen uptake kinetics. Ten trained cyclists, male (age: 25 ± 3.6 years, body mass: 67.2 ± 4.5 kg, height: 174.8 ± 6.5 cm and VO2max: 62.4 ± 3.1 mL.kg¹.min¹, performed two identical bouts transitions at constant load [mean ± SD (intensity 75%delta: 75% of the difference between the VO2 lactate threshold and the VO2max] in different days. The SC was calculated from different methods: (1 bi-exponential model [VO2(t = VO2base + A1 (1 e(tTA1

  11. SUSY QM from three domain walls in a scalar potential

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, R. de Lima; Lima, A.F. de [Universidade Federal de Campina Grande (UFCG), Campina Grande, PB (Brazil). Centro de Tecnologia. Unidade Academica de Fisica]. E-mail: aerlima@df.ufcg.edu.br; Bezerra de Mello, E.R.; Bezerra, V.B. [Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB (Brazil). Dept. de Fisica]. E-mails: emello@fisica.ufpb.br; valdir@fisica.ufpb.br

    2007-07-01

    We investigate the linear classical stability of Bogomol'nyi-Prasad-Sommerfield (BPS) on three domain wall solutions in a system of three coupled real scalar fields, for a general positive potential with a square form. From a field theoretic superpotential evaluated on the domain states, the connection between the supersymmetric quantum mechanics involving three-component eigenfunctions and the stability equation associated with three classical configurations is elaborated. (author)

  12. Magnetic domains in Ni-Mn-Ga martensitic thin films

    International Nuclear Information System (INIS)

    Chernenko, V A; Anton, R Lopez; Kohl, M; Ohtsuka, M; Orue, I; Barandiaran, J M

    2005-01-01

    A series of martensitic Ni 52 Mn 24 Ga 24 thin films deposited on alumina ceramic substrates has been prepared by using RF(radio-frequency) magnetron sputtering. The film thickness, d, varies from 0.1 to 5.0m. Magnetic domain patterns have been imaged by the MFM (magnetic force microscopy) technique. A maze domain structure is found for all studied films. MFM shows a large out-of-plane magnetization component and a rather uniform domain width for each film thickness. The domain width, δ, depends on the film thickness as δ∝√d in the whole studied range of film thickness. This dependence is the expected one for magnetic anisotropy and magnetostatic contributions in a perpendicular magnetic domain configuration. The proportionality coefficient is also consistent with the values of saturation magnetization and magnetic anisotropy determined in the samples

  13. Contribution of domain wall networks to the CMB power spectrum

    International Nuclear Information System (INIS)

    Lazanu, A.; Martins, C.J.A.P.; Shellard, E.P.S.

    2015-01-01

    We use three domain wall simulations from the radiation era to the late-time dark energy domination era based on the PRS algorithm to calculate the energy–momentum tensor components of domain wall networks in an expanding universe. Unequal time correlators in the radiation, matter and cosmological constant epochs are calculated using the scaling regime of each of the simulations. The CMB power spectrum of a network of domain walls is determined. The first ever quantitative constraint for the domain wall surface tension is obtained using a Markov chain Monte Carlo method; an energy scale of domain walls of 0.93 MeV, which is close but below the Zel'dovich bound, is determined

  14. Contribution of domain wall networks to the CMB power spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Lazanu, A., E-mail: A.Lazanu@damtp.cam.ac.uk [Centre for Theoretical Cosmology, Department of Applied Mathematics and Theoretical Physics, Wilberforce Road, Cambridge CB3 0WA (United Kingdom); Martins, C.J.A.P., E-mail: Carlos.Martins@astro.up.pt [Centro de Astrofísica, Universidade do Porto, Rua das Estrelas, 4150-762 Porto (Portugal); Instituto de Astrofísica e Ciências do Espaço, CAUP, Rua das Estrelas, 4150-762 Porto (Portugal); Shellard, E.P.S., E-mail: E.P.S.Shellard@damtp.cam.ac.uk [Centre for Theoretical Cosmology, Department of Applied Mathematics and Theoretical Physics, Wilberforce Road, Cambridge CB3 0WA (United Kingdom)

    2015-07-30

    We use three domain wall simulations from the radiation era to the late-time dark energy domination era based on the PRS algorithm to calculate the energy–momentum tensor components of domain wall networks in an expanding universe. Unequal time correlators in the radiation, matter and cosmological constant epochs are calculated using the scaling regime of each of the simulations. The CMB power spectrum of a network of domain walls is determined. The first ever quantitative constraint for the domain wall surface tension is obtained using a Markov chain Monte Carlo method; an energy scale of domain walls of 0.93 MeV, which is close but below the Zel'dovich bound, is determined.

  15. Contribution of domain wall networks to the CMB power spectrum

    Directory of Open Access Journals (Sweden)

    A. Lazanu

    2015-07-01

    Full Text Available We use three domain wall simulations from the radiation era to the late-time dark energy domination era based on the PRS algorithm to calculate the energy–momentum tensor components of domain wall networks in an expanding universe. Unequal time correlators in the radiation, matter and cosmological constant epochs are calculated using the scaling regime of each of the simulations. The CMB power spectrum of a network of domain walls is determined. The first ever quantitative constraint for the domain wall surface tension is obtained using a Markov chain Monte Carlo method; an energy scale of domain walls of 0.93 MeV, which is close but below the Zel'dovich bound, is determined.

  16. Methylation analysis of polysaccharides: Technical advice.

    Science.gov (United States)

    Sims, Ian M; Carnachan, Susan M; Bell, Tracey J; Hinkley, Simon F R

    2018-05-15

    Glycosyl linkage (methylation) analysis is used widely for the structural determination of oligo- and poly-saccharides. The procedure involves derivatisation of the individual component sugars of a polysaccharide to partially methylated alditol acetates which are analysed and quantified by gas chromatography-mass spectrometry. The linkage positions for each component sugar can be determined by correctly identifying the partially methylated alditol acetates. Although the methods are well established, there are many technical aspects to this procedure and both careful attention to detail and considerable experience are required to achieve a successful methylation analysis and to correctly interpret the data generated. The aim of this article is to provide the technical details and critical procedural steps necessary for a successful methylation analysis and to assist researchers (a) with interpreting data correctly and (b) in providing the comprehensive data required for reviewers to fully assess the work. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. Protein domain organisation: adding order

    Directory of Open Access Journals (Sweden)

    Kummerfeld Sarah K

    2009-01-01

    Full Text Available Abstract Background Domains are the building blocks of proteins. During evolution, they have been duplicated, fused and recombined, to produce proteins with novel structures and functions. Structural and genome-scale studies have shown that pairs or groups of domains observed together in a protein are almost always found in only one N to C terminal order and are the result of a single recombination event that has been propagated by duplication of the multi-domain unit. Previous studies of domain organisation have used graph theory to represent the co-occurrence of domains within proteins. We build on this approach by adding directionality to the graphs and connecting nodes based on their relative order in the protein. Most of the time, the linear order of domains is conserved. However, using the directed graph representation we have identified non-linear features of domain organization that are over-represented in genomes. Recognising these patterns and unravelling how they have arisen may allow us to understand the functional relationships between domains and understand how the protein repertoire has evolved. Results We identify groups of domains that are not linearly conserved, but instead have been shuffled during evolution so that they occur in multiple different orders. We consider 192 genomes across all three kingdoms of life and use domain and protein annotation to understand their functional significance. To identify these features and assess their statistical significance, we represent the linear order of domains in proteins as a directed graph and apply graph theoretical methods. We describe two higher-order patterns of domain organisation: clusters and bi-directionally associated domain pairs and explore their functional importance and phylogenetic conservation. Conclusion Taking into account the order of domains, we have derived a novel picture of global protein organization. We found that all genomes have a higher than expected

  18. Protein domain organisation: adding order.

    Science.gov (United States)

    Kummerfeld, Sarah K; Teichmann, Sarah A

    2009-01-29

    Domains are the building blocks of proteins. During evolution, they have been duplicated, fused and recombined, to produce proteins with novel structures and functions. Structural and genome-scale studies have shown that pairs or groups of domains observed together in a protein are almost always found in only one N to C terminal order and are the result of a single recombination event that has been propagated by duplication of the multi-domain unit. Previous studies of domain organisation have used graph theory to represent the co-occurrence of domains within proteins. We build on this approach by adding directionality to the graphs and connecting nodes based on their relative order in the protein. Most of the time, the linear order of domains is conserved. However, using the directed graph representation we have identified non-linear features of domain organization that are over-represented in genomes. Recognising these patterns and unravelling how they have arisen may allow us to understand the functional relationships between domains and understand how the protein repertoire has evolved. We identify groups of domains that are not linearly conserved, but instead have been shuffled during evolution so that they occur in multiple different orders. We consider 192 genomes across all three kingdoms of life and use domain and protein annotation to understand their functional significance. To identify these features and assess their statistical significance, we represent the linear order of domains in proteins as a directed graph and apply graph theoretical methods. We describe two higher-order patterns of domain organisation: clusters and bi-directionally associated domain pairs and explore their functional importance and phylogenetic conservation. Taking into account the order of domains, we have derived a novel picture of global protein organization. We found that all genomes have a higher than expected degree of clustering and more domain pairs in forward and

  19. Prediction Reweighting for Domain Adaptation.

    Science.gov (United States)

    Shuang Li; Shiji Song; Gao Huang

    2017-07-01

    There are plenty of classification methods that perform well when training and testing data are drawn from the same distribution. However, in real applications, this condition may be violated, which causes degradation of classification accuracy. Domain adaptation is an effective approach to address this problem. In this paper, we propose a general domain adaptation framework from the perspective of prediction reweighting, from which a novel approach is derived. Different from the major domain adaptation methods, our idea is to reweight predictions of the training classifier on testing data according to their signed distance to the domain separator, which is a classifier that distinguishes training data (from source domain) and testing data (from target domain). We then propagate the labels of target instances with larger weights to ones with smaller weights by introducing a manifold regularization method. It can be proved that our reweighting scheme effectively brings the source and target domains closer to each other in an appropriate sense, such that classification in target domain becomes easier. The proposed method can be implemented efficiently by a simple two-stage algorithm, and the target classifier has a closed-form solution. The effectiveness of our approach is verified by the experiments on artificial datasets and two standard benchmarks, a visual object recognition task and a cross-domain sentiment analysis of text. Experimental results demonstrate that our method is competitive with the state-of-the-art domain adaptation algorithms.

  20. Importance of the Alternative Five and Trait Emotional Intelligence for Agentic and Communal Domains of Satisfaction

    Directory of Open Access Journals (Sweden)

    Andreja Avsec

    2011-12-01

    Full Text Available Many studies supported the importance of trait emotional intelligence (EI for subjective well-being but specific domains of life-satisfaction were rarely of interest. Our study investigated whether emotional intelligence is more important for interpersonal or communal-related domains (e.g. satisfaction with friends, intimate partners than for agentic domains of satisfaction (e.g. satisfaction with finances, work. Due to the problematic differential validity of trait EI from personality, the relationship between trait EI and domains of satisfaction was controlled for by personality. Slovene students and young adults (N=442 completed the Emotional Skills and Competence Questionnaire and the Zuckerman-Kuhlman Personality Questionnaire, and rated their satisfaction with 12 aspects of life. Principal component analysis of these domains revealed three components, explaining 62% of total variance. The communal domains included self-reported satisfaction with popularity, respect, influence on others, family relationships, and intimate relationship. The agentic domains included satisfaction with professional carrier, financial situation, academic education, and achieved goals. The physical domains component was comprised of satisfaction with appearance, fitness, and health. After accounting for personality, trait EI explained 16% of variance in communal domain and 10% of variance in agentic domain, thus suggesting greater importance of trait EI for interpersonal domains. However, trait EI seems to play an important role for satisfaction in the agentic domains also, as successful management of our emotions can help us reach our goals and thus be more satisfied.

  1. Technical training: places available

    CERN Document Server

    2013-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924)   Electronics design Next Session Duration Language Introduction to VHDL 21-Feb-13 to 22-Feb-13 2 days English Mechanical design Next Session Duration Language ANSYS - Introduction à ANSYS Mechanical APDL 04-Feb-13 to 07-Feb-13 4 days English Applications de la cotation fonctionnelle et du langage ISO 06-Feb-13 to 08-Feb-13 2 days 4 hours French CATIA V5 – Surfacique 14-Jan-13 to 15-Jan-13 2 days French Office software Next Session Duration Language ACCESS 2010 - niveau 2 : ECDL 06-Feb-13 to 07-Feb-13 2 days French Dreamweaver CS3 - Niveau 1 14-Jan-13 to 15-Jan-13 2 d...

  2. Technical training - Places available

    CERN Document Server

    2012-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924)   Electronics design Next Session Duration Language Availability Certified LabVIEW Associate Developer (CLAD) 06-Dec-12 to 06-Dec-12 1 hour English One more place available Compatibilité électromagnetique (CEM): Applications 23-Nov-12 to 23-Nov-12 3.5 hours English 3 places available Compatibilité électromagnétique (CEM): Introduction 23-Nov-12 to 23-Nov-12 3 hours English 43 places available Effets des Radiations sur les composants et systèmes électroniques 11-Dec-12 to 12-Dec-12 1 day 4 hours French 9 places available LabVIEW for beginners ...

  3. Technical training - places available

    CERN Multimedia

    2012-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924) HR Department »Electronics design Next Session Duration Language Availability Comprehensive VHDL for FPGA Design 08-Oct-12 to 12-Oct-12 5 days English 3 places available Foundations of Electromagnetism and Magnet Design (EMAG) 14-Nov-12 to 27-Nov-12 6 days English 20 places available Impacts de la suppression du plomb (RoHS) en électronique 26-Oct-12 to 26-Oct-12 8 hours French 15 places available Introduction to VHDL 10-Oct-12 to 11-Oct-12 2 days English 7 places available LabVIEW Real Time and FPGA 13-Nov-12 to 16-Nov-12 5 days French 5 places available »Mechanical design Next Se...

  4. Problems of technical cooperation

    International Nuclear Information System (INIS)

    Noramli, M.

    1987-01-01

    The main principles of the IAEA technical co-operation program, which intends to answer the requirements of the member states as regards technical assistance, are presented. IAEA offers its assistance in the supervision and financial support of the projects, which promise direct and quick profit to the member states. Projects related to the satisfaction of the main demands of humanity, industrial use, energy generation, radiation protection and other fields, which can promote the contribution of nuclear power generation to the course of peace, protection of health and thriving of states, are among them. 35 million dollars (USA) was allocated for the IAEA technical assistance and realization of the co-operation program in 1987

  5. Fuel Element Technical Manual

    Energy Technology Data Exchange (ETDEWEB)

    Burley, H.H. [ed.

    1956-08-01

    It is the purpose of the Fuel Element Technical Manual to Provide a single document describing the fabrication processes used in the manufacture of the fuel element as well as the technical bases for these processes. The manual will be instrumental in the indoctrination of personnel new to the field and will provide a single data reference for all personnel involved in the design or manufacture of the fuel element. The material contained in this manual was assembled by members of the Engineering Department and the Manufacturing Department at the Hanford Atomic Products Operation between the dates October, 1955 and June, 1956. Arrangement of the manual. The manual is divided into six parts: Part I--introduction; Part II--technical bases; Part III--process; Part IV--plant and equipment; Part V--process control and improvement; and VI--safety.

  6. Yucca Mountain Climate Technical Support Representative

    International Nuclear Information System (INIS)

    Sharpe, Saxon E

    2007-01-01

    The primary objective of Project Activity ORD-FY04-012, 'Yucca Mountain Climate Technical Support Representative', was to provide the Office of Civilian Radioactive Waste Management (OCRWM) with expertise on past, present, and future climate scenarios and to support the technical elements of the Yucca Mountain Project (YMP) climate program. The Climate Technical Support Representative was to explain, defend, and interpret the YMP climate program to the various audiences during Site Recommendation and License Application. This technical support representative was to support DOE management in the preparation and review of documents, and to participate in comment response for the Final Environmental Impact Statement, the Site Recommendation Hearings, the NRC Sufficiency Comments, and other forums as designated by DOE management. Because the activity was terminated 12 months early and experience a 27% reduction in budget, it was not possible to complete all components of the tasks as originally envisioned. Activities not completed include the qualification of climate datasets and the production of a qualified technical report. The following final report is an unqualified summary of the activities that were completed given the reduced time and funding

  7. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2009-01-01

    Are you running Vista on your new PC – or are you planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual session of this course will take place on 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at mailto:Technical.Training@cern.ch

  8. Transformation of technical infrastructure

    DEFF Research Database (Denmark)

    Nielsen, Susanne Balslev

    , the evolution of large technological systems and theories about organisational and technological transformationprocesses. The empirical work consist of three analysis at three different levels: socio-technical descriptions of each sector, an envestigation of one municipality and envestigations of one workshop......The scope of the project is to investigate the possibillities of - and the barriers for a transformation of technical infrastructure conserning energy, water and waste. It focus on urban ecology as a transformation strategy. The theoretical background of the project is theories about infrastructure...

  9. KSC Technical Capabilities Website

    Science.gov (United States)

    Nufer, Brian; Bursian, Henry; Brown, Laurette L.

    2010-01-01

    This document is the website pages that review the technical capabilities that the Kennedy Space Center (KSC) has for partnership opportunities. The purpose of this information is to make prospective customers aware of the capabilities and provide an opportunity to form relationships with the experts at KSC. The technical capabilities fall into these areas: (1) Ground Operations and Processing Services, (2) Design and Analysis Solutions, (3) Command and Control Systems / Services, (4) Materials and Processes, (5) Research and Technology Development and (6) Laboratories, Shops and Test Facilities.

  10. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    Are you running Vista on your new PC – or are planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual sessions of this course will take place on 12 December 2008 and 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at Technical.Training@cern.ch

  11. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    You are running Vista on your new PC – or are planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual sessions of this course will take place on 12 December 2008 and 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at mailto:Technical.Training@cern.ch

  12. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    Are you running Vista on your new PC – or are you planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual sessions of this course will take place on 12 December 2008 and 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at mailto:Technical.Training@cern.ch

  13. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    You are running Vista on your new PC – or are planning to install it? The Technical Training service is organizing a half-day training on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced using Windows XP. The next bilingual sessions of this course will take place on December 12, 2008 and January 30, 2009. Register using our catalogue : http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at Technical.Training@cern.ch

  14. Technical memory 2007

    International Nuclear Information System (INIS)

    2009-01-01

    The technical memory 2007 of the Nuclear Regulatory Authority (ARN) of the Argentine Republic, compiles the papers published in the subject on radiation protection and nuclear safety, and presented in journals, technical reports, congress or meetings of these specialities by personnel of the mentioned institution during 2007. In this edition the documents are presented on: environmental protection; transport of radioactive materials; regulations; research reactors and nuclear power plants; biological radiation effects; therapeutic uses of ionizing radiation and radioprotection of patients; internal dosimetry; physical dosimetry; knowledge management; radioactive waste management [es

  15. Restoration the domain structure from magnetic force microscopy image

    Science.gov (United States)

    Wu, Dongping; Lou, Yuanfu; Wei, Fulin; Wei, Dan

    2012-04-01

    This contribution gives an approximation method to calculate the stray field of the scanning plane from the magnetic force microscopy (MFM) force gradient image. Before calculation, a Butterworth low-pass filter has been used to remove a part of the noise of the image. The discrete Fourier transform (DFT) method has been used to calculate the magnetic potential of the film surface. It shows that the potential is not correct because the low-frequency noise has been enlarged. The approximation method gives a better result of the potential and proves that the MFM force gradient of the perpendicular component image also gives the perpendicular component of the stray field. Supposing that the distance between the tip and the sample is as small as near zero, the force gradient image also gives the magnetic charge distribution of the film surface. So if the orientation of the film from hysteresis loop is known, then the domain structure of the film can be determined. For perpendicular orientation, the absolution value of the perpendicular component of stray field gives the domain and domain wall position. For in-plane orientation, the absolution value of in-plane component of stray field gives the domain and domain wall position.

  16. A quasi-distributed temperature sensor interrogated by a wavelength-sensitive optical time-domain reflectometer

    International Nuclear Information System (INIS)

    Crunelle, C; Wuilpart, M; Caucheteur, C; Mégret, P

    2009-01-01

    In this note, we present a quasi-distributed temperature monitoring system based on the concatenation of identical low-reflective fiber Bragg gratings (FBGs) and interrogated by means of an optical time-domain reflectometer (OTDR). An original wavelength-sensitive system placed before the OTDR detector is used to analyze the reflected signal. This system allows the height of the FBG reflection peaks in the OTDR trace to depend on their resonance wavelength, and therefore to the local temperature. In addition, a simple but original reference method is proposed. The configuration of the whole interrogating device is kept very basic, as a standard OTDR and some passive components are used. The cost of the overall system is therefore very limited. In this note, the wavelength-sensitive system is studied in details, as well as the reference method. Experimental results are reported. (technical design note)

  17. Modelling and Reasoning about Security Requirements in Socio-Technical Systems

    NARCIS (Netherlands)

    Paja, Elda; Dalpiaz, Fabiano; Giorgini, Paolo

    2015-01-01

    Modern software systems operate within the context of larger socio-technical systems, wherein they interact—by exchanging data and outsourcing tasks—with other technical components, humans, and organisations. When interacting, these components (actors) operate autonomously; as such, they may

  18. Multifunctionalities driven by ferroic domains

    Science.gov (United States)

    Yang, J. C.; Huang, Y. L.; He, Q.; Chu, Y. H.

    2014-08-01

    Considerable attention has been paid to ferroic systems in pursuit of advanced applications in past decades. Most recently, the emergence and development of multiferroics, which exhibit the coexistence of different ferroic natures, has offered a new route to create functionalities in the system. In this manuscript, we step from domain engineering to explore a roadmap for discovering intriguing phenomena and multifunctionalities driven by periodic domain patters. As-grown periodic domains, offering exotic order parameters, periodic local perturbations and the capability of tailoring local spin, charge, orbital and lattice degrees of freedom, are introduced as modeling templates for fundamental studies and novel applications. We discuss related significant findings on ferroic domain, nanoscopic domain walls, and conjunct heterostructures based on the well-organized domain patterns, and end with future prospects and challenges in the field.

  19. Fourier Domain Sensing

    Science.gov (United States)

    Feldkhun, Daniel (Inventor); Wagner, Kelvin H. (Inventor)

    2013-01-01

    Methods and systems are disclosed of sensing an object. A first radiation is spatially modulated to generate a structured second radiation. The object is illuminated with the structured second radiation such that the object produces a third radiation in response. Apart from any spatially dependent delay, a time variation of the third radiation is spatially independent. With a single-element detector, a portion of the third radiation is detected from locations on the object simultaneously. At least one characteristic of a sinusoidal spatial Fourier-transform component of the object is estimated from a time-varying signal from the detected portion of the third radiation.

  20. Mapping the Moral Domain

    Science.gov (United States)

    Graham, Jesse; Nosek, Brian A.; Haidt, Jonathan; Iyer, Ravi; Koleva, Spassena; Ditto, Peter H.

    2010-01-01

    The moral domain is broader than the empathy and justice concerns assessed by existing measures of moral competence, and it is not just a subset of the values assessed by value inventories. To fill the need for reliable and theoretically-grounded measurement of the full range of moral concerns, we developed the Moral Foundations Questionnaire (MFQ) based on a theoretical model of five universally available (but variably developed) sets of moral intuitions: Harm/care, Fairness/reciprocity, Ingroup/loyalty, Authority/respect, and Purity/sanctity. We present evidence for the internal and external validity of the scale and the model, and in doing so present new findings about morality: 1. Comparative model fitting of confirmatory factor analyses provides empirical justification for a five-factor structure of moral concerns. 2. Convergent/discriminant validity evidence suggests that moral concerns predict personality features and social group attitudes not previously considered morally relevant. 3. We establish pragmatic validity of the measure in providing new knowledge and research opportunities concerning demographic and cultural differences in moral intuitions. These analyses provide evidence for the usefulness of Moral Foundations Theory in simultaneously increasing the scope and sharpening the resolution of psychological views of morality. PMID:21244182

  1. Selection and Evaluation of Priority Domains in Global Energy Internet Standard Development Based on Technology Foresight

    Science.gov (United States)

    Jin, Yang; Ciwei, Gao; Jing, Zhang; Min, Sun; Jie, Yu

    2017-05-01

    The selection and evaluation of priority domains in Global Energy Internet standard development will help to break through limits of national investment, thus priority will be given to standardizing technical areas with highest urgency and feasibility. Therefore, in this paper, the process of Delphi survey based on technology foresight is put forward, the evaluation index system of priority domains is established, and the index calculation method is determined. Afterwards, statistical method is used to evaluate the alternative domains. Finally the top four priority domains are determined as follows: Interconnected Network Planning and Simulation Analysis, Interconnected Network Safety Control and Protection, Intelligent Power Transmission and Transformation, and Internet of Things.

  2. Component-Based Approach in Learning Management System Development

    Science.gov (United States)

    Zaitseva, Larisa; Bule, Jekaterina; Makarov, Sergey

    2013-01-01

    The paper describes component-based approach (CBA) for learning management system development. Learning object as components of e-learning courses and their metadata is considered. The architecture of learning management system based on CBA being developed in Riga Technical University, namely its architecture, elements and possibilities are…

  3. RCM and component evaluation logic

    International Nuclear Information System (INIS)

    Davis, B.; Anderson, J.

    1991-01-01

    This paper reports on the prevention maintenance program at Palo Verde Nuclear Generating Station (PVNGS), initially developed based on recommendations found in vendor technical manuals and accepted industry standards. The method was used until there was sufficient operating history to justify changes. The Reliability Centered Maintenance (RCM) project was started to provide another approach to the implementation of preventive maintenance. RCM evaluations were performed on nine systems. RCM was then suspended since it was found during implementation that additional documentation was necessary. RCM was selected as a preventive maintenance development process because it provides a documented analytical approach to establishing a preventive maintenance program. It is also being developed throughout the industry as a standard approach to preventive maintenance. PVNGS became interested in performing RCM analyses primarily to ensure that system and component reliability is maintained at the highest level possible and that hidden or rare failures are addressed by appropriate and effective maintenance. A secondary reason was to save maintenance expenditures

  4. Structural analysis of nuclear components

    International Nuclear Information System (INIS)

    Ikonen, K.; Hyppoenen, P.; Mikkola, T.; Noro, H.; Raiko, H.; Salminen, P.; Talja, H.

    1983-05-01

    THe report describes the activities accomplished in the project 'Structural Analysis Project of Nuclear Power Plant Components' during the years 1974-1982 in the Nuclear Engineering Laboratory at the Technical Research Centre of Finland. The objective of the project has been to develop Finnish expertise in structural mechanics related to nuclear engineering. The report describes the starting point of the research work, the organization of the project and the research activities on various subareas. Further the work done with computer codes is described and also the problems which the developed expertise has been applied to. Finally, the diploma works, publications and work reports, which are mainly in Finnish, are listed to give a view of the content of the project. (author)

  5. Domain wall networks on solitons

    International Nuclear Information System (INIS)

    Sutcliffe, Paul

    2003-01-01

    Domain wall networks on the surface of a soliton are studied in a simple theory. It consists of two complex scalar fields, in 3+1 dimensions, with a global U(1)xZ n symmetry, where n>2. Solutions are computed numerically in which one of the fields forms a Q ball and the other field forms a network of domain walls localized on the surface of the Q ball. Examples are presented in which the domain walls lie along the edges of a spherical polyhedron, forming junctions at its vertices. It is explained why only a small restricted class of polyhedra can arise as domain wall networks

  6. Topological domain walls in helimagnets

    Science.gov (United States)

    Schoenherr, P.; Müller, J.; Köhler, L.; Rosch, A.; Kanazawa, N.; Tokura, Y.; Garst, M.; Meier, D.

    2018-05-01

    Domain walls naturally arise whenever a symmetry is spontaneously broken. They interconnect regions with different realizations of the broken symmetry, promoting structure formation from cosmological length scales to the atomic level1,2. In ferroelectric and ferromagnetic materials, domain walls with unique functionalities emerge, holding great promise for nanoelectronics and spintronics applications3-5. These walls are usually of Ising, Bloch or Néel type and separate homogeneously ordered domains. Here we demonstrate that a wide variety of new domain walls occurs in the presence of spatially modulated domain states. Using magnetic force microscopy and micromagnetic simulations, we show three fundamental classes of domain walls to arise in the near-room-temperature helimagnet iron germanium. In contrast to conventional ferroics, the domain walls exhibit a well-defined inner structure, which—analogous to cholesteric liquid crystals—consists of topological disclination and dislocation defects. Similar to the magnetic skyrmions that form in the same material6,7, the domain walls can carry a finite topological charge, permitting an efficient coupling to spin currents and contributions to a topological Hall effect. Our study establishes a new family of magnetic nano-objects with non-trivial topology, opening the door to innovative device concepts based on helimagnetic domain walls.

  7. Routledge French technical dictionary

    CERN Document Server

    1994-01-01

    The French-English volume of this highly acclaimed set consists of some 100,000 keywords in both French and English, drawn from the whole range of modern applied science and technical terminology. Covers over 70 subject areas, from engineering and chemistry to packaging, transportation, data processing and much more.

  8. Technical objectives of inspection

    International Nuclear Information System (INIS)

    Sorenson, R.J.; Stewart, K.B.; Schneider, R.A.

    1976-01-01

    The various technical objectives of inspection are discussed in a very general manner. The discussion includes how the inspection function is related to the assumed threat, the various degrees of assurance and reliance on criteria, and the hierarchy of assurance which is obtained from the various types or levels of inspection

  9. NUSC Technical Publications Guide.

    Science.gov (United States)

    1985-05-01

    Facility personnel especially that of A. Castelluzzo, E. Deland, J. Gesel , and E. Szlosek (all of Code 4343). Reviewed and Approved: 14 July 1980 D...their technical content and format. Review and approve the manual outline, the review manuscript, and the final camera - reproducible copy. Conduct in

  10. ITER EDA technical activities

    International Nuclear Information System (INIS)

    Aymar, R.

    1998-01-01

    Six years of technical work under the ITER EDA Agreement have resulted in a design which constitutes a complete description of the ITER device and of its auxiliary systems and facilities. The ITER Council commented that the Final Design Report provides the first comprehensive design of a fusion reactor based on well established physics and technology

  11. Technical basis of safeguards

    International Nuclear Information System (INIS)

    Buechler, C.

    1975-01-01

    Definition of nuclear materials control. Materials accountancy and physical control as technical possibilities. Legal possibilities and levels of responsibility: material holders, national and international authority. Detection vs. prevention. Physical security and containment surveillance. Accountancy: materials balance concept. Materials measurement: inventory taking, flow determination. IAEA safeguards; verification of operator's statement. (HP) [de

  12. Technical memory 1999

    International Nuclear Information System (INIS)

    2000-01-01

    The technical memory 1999 of the Nuclear Regulatory Authority (NRA) of the Argentine Republic, compile the papers published in the subject on radiation protection and nuclear safety, safeguards and physical protection, and presented in congress or meetings of these specialities by personnel of the mentioned institution during 1999

  13. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: LabVIEW Real-Time (F) : 7 - 9.6.2005 (3 jours) LabVIEW Migration 6 to 7: 14.6.2005 (1 day) IT3T/1 - Read your mail and more with Outlook 2003 : 14.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/2 - Creating, managing and using distribution lists with Simba2 : 16.6.2005 (IT Technical Training Tutorial, free of charge) FrontPage 2003 - niveau 2 : 16 & 17.6.2005 (2 jours) Utilisation de fichiers PDF avec ACROBAT 6.0 : 20.6.2005 (1journée) Introduction to ANSYS: 21 - 24.6.2005 (4 days) IT3T/3 - Working remotely with Windows XP : 28.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/4 - Editing Websites with Frontpage 2003 : 30.6.2005 (IT Technical Training Tutorial, free of charge) WORD 2003 (Short Course I) - HowTo... Work with repetitive tasks /AutoText, AutoFormat, AutoC...

  14. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    John Ross

    2003-04-30

    The Final Technical Report summarizes research accomplishments and Publications in the period of 5/1/99 to 4/30/03 done on the grant. Extensive progress was made in the period covered by this report in the areas of chemical kinetics of non-linear systems; spatial structures, reaction - diffusion systems, and thermodynamic and stochastic theory of electrochemical and general systems.

  15. Materials Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-08-01

    Roadmap identifying the efforts of the Materials Technical Team (MTT) to focus primarily on reducing the mass of structural systems such as the body and chassis in light-duty vehicles (including passenger cars and light trucks) which enables improved vehicle efficiency regardless of the vehicle size or propulsion system employed.

  16. Technical Writing in Hydrogeology.

    Science.gov (United States)

    Tinker, John R., Jr.

    1986-01-01

    A project for Writing Across the Curriculum at the University of Wisconsin-Eau Claire is described as a method to relate the process of writing to the process of learning hydrology. The project focuses on an actual groundwater contamination case and is designed to improve the technical writing skills of students. (JN)

  17. PISA 2009 Technical Report

    Science.gov (United States)

    OECD Publishing (NJ1), 2012

    2012-01-01

    The "PISA 2009 Technical Report" describes the methodology underlying the PISA 2009 survey. It examines additional features related to the implementation of the project at a level of detail that allows researchers to understand and replicate its analyses. The reader will find a wealth of information on the test and sample design,…

  18. PISA 2012 Technical Report

    Science.gov (United States)

    OECD Publishing, 2014

    2014-01-01

    The "PISA 2012 Technical Report" describes the methodology underlying the PISA 2012 survey, which tested 15-year-olds' competencies in mathematics, reading and science and, in some countries, problem solving and financial literacy. It examines the design and implementation of the project at a level of detail that allows researchers to…

  19. New usable technical specifications

    International Nuclear Information System (INIS)

    Webster, S.A.; Tomasi, L.T.; Bernier, R.A.

    1989-01-01

    After 2 yr of preparation, 1988 finally saw the nuclear industry writing operator-oriented technical specifications. This effort is a continuation of previous efforts to develop improved and usable standard technical specifications (STSs), and is being conducted by the four nuclear steam supply system vendor owners' groups under the auspices of the Nuclear Management Resources Council. Each participant is currently preparing a set of improved STSs based on a writer's guide that was developed through a combined industry effort. In May of 1987, a Human Factors Improvements to Technical Specifications (HFITS) task group was formed to prepare a writer's guide for improved, industrywide STSs. This task group was composed of two representatives from each owners' group, one with a human factors background and one with some operations background. Two documents were prepared in 6 months, a human factors report laying the groundwork for the considerations to go into technical specifications and a writer's guide for their preparation. This paper reports on the application of this writer's guide to the writing of improved STS

  20. The BRCT domain is a phospho-protein binding domain.

    Science.gov (United States)

    Yu, Xiaochun; Chini, Claudia Christiano Silva; He, Miao; Mer, Georges; Chen, Junjie

    2003-10-24

    The carboxyl-terminal domain (BRCT) of the Breast Cancer Gene 1 (BRCA1) protein is an evolutionarily conserved module that exists in a large number of proteins from prokaryotes to eukaryotes. Although most BRCT domain-containing proteins participate in DNA-damage checkpoint or DNA-repair pathways, or both, the function of the BRCT domain is not fully understood. We show that the BRCA1 BRCT domain directly interacts with phosphorylated BRCA1-Associated Carboxyl-terminal Helicase (BACH1). This specific interaction between BRCA1 and phosphorylated BACH1 is cell cycle regulated and is required for DNA damage-induced checkpoint control during the transition from G2 to M phase of the cell cycle. Further, we show that two other BRCT domains interact with their respective physiological partners in a phosphorylation-dependent manner. Thirteen additional BRCT domains also preferentially bind phospho-peptides rather than nonphosphorylated control peptides. These data imply that the BRCT domain is a phospho-protein binding domain involved in cell cycle control.

  1. Reusable Component Services

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Reusable Component Services (RCS) is a super-catalog of components, services, solutions and technologies that facilitates search, discovery and collaboration in...

  2. Assessment of technical and nontechnical skills in surgical residents.

    Science.gov (United States)

    Ponton-Carss, Alicia; Kortbeek, John B; Ma, Irene W Y

    2016-11-01

    Surgical competence encompasses both technical and nontechnical skills. This study seeks to evaluate the validity evidence for a comprehensive surgical skills examination and to examine the relationship between technical and nontechnical skills. Six examination stations assessing both technical and nontechnical skills, conducted yearly for surgical trainees (n = 120) between 2010 and 2014 are included. The assessment tools demonstrated acceptable internal consistency. Interstation reliability for technical skills was low (alpha = .39). Interstation reliability for the nontechnical skills was lower (alpha range -.05 to .31). Nontechnical skills domains were strongly correlated, ranging from r = .65, P skills were inconsistent, ranging from poor (r = -.06; P = .54) to moderate (r = .45; P skills are necessary to assess overall surgical competency. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Software component quality evaluation

    Science.gov (United States)

    Clough, A. J.

    1991-01-01

    The paper describes a software inspection process that can be used to evaluate the quality of software components. Quality criteria, process application, independent testing of the process and proposed associated tool support are covered. Early results indicate that this technique is well suited for assessing software component quality in a standardized fashion. With automated machine assistance to facilitate both the evaluation and selection of software components, such a technique should promote effective reuse of software components.

  4. Reactor component automatic grapple

    International Nuclear Information System (INIS)

    Greenaway, P.R.

    1982-01-01

    A grapple for handling nuclear reactor components in a medium such as liquid sodium which, upon proper seating and alignment of the grapple with the component as sensed by a mechanical logic integral to the grapple, automatically seizes the component. The mechanical logic system also precludes seizure in the absence of proper seating and alignment. (author)

  5. Repurposing learning object components

    NARCIS (Netherlands)

    Verbert, K.; Jovanovic, J.; Gasevic, D.; Duval, E.; Meersman, R.

    2005-01-01

    This paper presents an ontology-based framework for repurposing learning object components. Unlike the usual practice where learning object components are assembled manually, the proposed framework enables on-the-fly access and repurposing of learning object components. The framework supports two

  6. Composing simulations using persistent software components

    Energy Technology Data Exchange (ETDEWEB)

    Holland, J.V.; Michelsen, R.E.; Powell, D.R.; Upton, S.C.; Thompson, D.R.

    1999-03-01

    The traditional process for developing large-scale simulations is cumbersome, time consuming, costly, and in some cases, inadequate. The topics of software components and component-based software engineering are being explored by software professionals in academic and industrial settings. A component is a well-delineated, relatively independent, and replaceable part of a software system that performs a specific function. Many researchers have addressed the potential to derive a component-based approach to simulations in general, and a few have focused on military simulations in particular. In a component-based approach, functional or logical blocks of the simulation entities are represented as coherent collections of components satisfying explicitly defined interface requirements. A simulation is a top-level aggregate comprised of a collection of components that interact with each other in the context of a simulated environment. A component may represent a simulation artifact, an agent, or any entity that can generated events affecting itself, other simulated entities, or the state of the system. The component-based approach promotes code reuse, contributes to reducing time spent validating or verifying models, and promises to reduce the cost of development while still delivering tailored simulations specific to analysis questions. The Integrated Virtual Environment for Simulation (IVES) is a composition-centered framework to achieve this potential. IVES is a Java implementation of simulation composition concepts developed at Los Alamos National Laboratory for use in several application domains. In this paper, its use in the military domain is demonstrated via the simulation of dismounted infantry in an urban environment.

  7. Resource Unavailability (RU) Per Domain Behavior

    NARCIS (Netherlands)

    Karagiannis, Georgios; Westberg, L.; Bader, A.; Tschofenig, Hannes; Tschofenig, H.

    2006-01-01

    This draft specifies a Per Domain Behavior that provides the ability to Diffserv nodes located outside Diffserv domain(s), e.g., receiver or other Diffserv enabled router to detect when the resources provided by the Diffserv domain(s) are not available. The unavailability of resources in the domain

  8. Taxonomies of Educational Objective Domain

    OpenAIRE

    Eman Ghanem Nayef; Nik Rosila Nik Yaacob; Hairul Nizam Ismail

    2013-01-01

    This paper highlights an effort to study the educational objective domain taxonomies including Bloom’s taxonomy, Lorin Anderson’s taxonomy, and Wilson’s taxonomy. In this study a comparison among these three taxonomies have been done. Results show that Bloom’s taxonomy is more suitable as an analysis tool to Educational Objective domain.

  9. Texture of lipid bilayer domains

    DEFF Research Database (Denmark)

    Jensen, Uffe Bernchou; Brewer, Jonathan R.; Midtiby, Henrik Skov

    2009-01-01

    We investigate the texture of gel (g) domains in binary lipid membranes composed of the phospholipids DPPC and DOPC. Lateral organization of lipid bilayer membranes is a topic of fundamental and biological importance. Whereas questions related to size and composition of fluid membrane domain...... are well studied, the possibility of texture in gel domains has so far not been examined. When using polarized light for two-photon excitation of the fluorescent lipid probe Laurdan, the emission intensity is highly sensitive to the angle between the polarization and the tilt orientation of lipid acyl...... chains. By imaging the intensity variations as a function of the polarization angle, we map the lateral variations of the lipid tilt within domains. Results reveal that gel domains are composed of subdomains with different lipid tilt directions. We have applied a Fourier decomposition method...

  10. Markets, Availability, Notice, and Technical Performance of Terahertz Systems: Historic Development, Present, and Trends

    Science.gov (United States)

    Hochrein, Thomas

    2015-03-01

    Although a lot of work has already been done under the older terms "far infrared" or "sub-millimeter waves", the term "terahertz" stands for a novel technique offering many potential applications. The latter term also represents a new generation of systems with the opportunity for coherent, time-resolved detection. In addition to the well-known technical opportunities, an historical examination of Internet usage, as well as the number of publications and patent applications, confirms ongoing interest in this technique. These activities' annual growth rate is between 9 % and 21 %. The geographical distribution shows the center of terahertz activities. A shift from the scientific to more application-oriented research can be observed. We present a survey among worldwide terahertz suppliers with special focus on the European region and the use of terahertz systems in the field of measurement and analytical applications. This reveals the current state of terahertz systems' commercial and geographical availability as well as their costs, target markets, and technical performance. Component cost distribution using the example of an optical pulsed time-domain terahertz system gives an impression of the prevailing cost structure. The predication regarding prospective market development, decreasing system costs and higher availability shows a convenient situation for potential users and interested customers. The causes are primarily increased competition and larger quantities in the future.

  11. The assessment of technical risks

    International Nuclear Information System (INIS)

    Jaeger, T.A.

    1978-01-01

    The safety of technical systems is so difficult to assess because the concept 'risk' contains technical-scientific factors as well as components of individual and social psychology. Immediate or short-term hazards of human life as i.e. caused by the operation of industrial plants and mediate and thus long-term hazards have to be distinguished. Characteristic for the second hazard groups is the great time-lag before the effect takes place. Thus a causal relationship can be recognized only late and not definitely. Even when the causes have been obviated the effects still show. The development of a systems-analytical model as a basis of decisive processes for the introduction of highly endangered large-scale technologies seems particularly difficult. A starting point for the quantification of the risk can still be seen in the product of the probability of realization and the extent of the damage. Public opinion, however, does not base its evaluations on an objective concept of risk but tends to have an attitude of aversion against great and disastrous accidents. On the other hand, plenty of slight accidents are accepted much more easily, even when the amount of deadly victims from accidents reaches dimensions beyond those of the rare large-scale accidents. Here, mostly the damage possible but not the probability of its occurence is seen, let alone the general use of the new technology. The value of the mathematical models for estimating risks is mainly due to the fact that they are able to clear up decisions. (orig./HP) [de

  12. Polar Domain Discovery with Sparkler

    Science.gov (United States)

    Duerr, R.; Khalsa, S. J. S.; Mattmann, C. A.; Ottilingam, N. K.; Singh, K.; Lopez, L. A.

    2017-12-01

    The scientific web is vast and ever growing. It encompasses millions of textual, scientific and multimedia documents describing research in a multitude of scientific streams. Most of these documents are hidden behind forms which require user action to retrieve and thus can't be directly accessed by content crawlers. These documents are hosted on web servers across the world, most often on outdated hardware and network infrastructure. Hence it is difficult and time-consuming to aggregate documents from the scientific web, especially those relevant to a specific domain. Thus generating meaningful domain-specific insights is currently difficult. We present an automated discovery system (Figure 1) using Sparkler, an open-source, extensible, horizontally scalable crawler which facilitates high throughput and focused crawling of documents pertinent to a particular domain such as information about polar regions. With this set of highly domain relevant documents, we show that it is possible to answer analytical questions about that domain. Our domain discovery algorithm leverages prior domain knowledge to reach out to commercial/scientific search engines to generate seed URLs. Subject matter experts then annotate these seed URLs manually on a scale from highly relevant to irrelevant. We leverage this annotated dataset to train a machine learning model which predicts the `domain relevance' of a given document. We extend Sparkler with this model to focus crawling on documents relevant to that domain. Sparkler avoids disruption of service by 1) partitioning URLs by hostname such that every node gets a different host to crawl and by 2) inserting delays between subsequent requests. With an NSF-funded supercomputer Wrangler, we scaled our domain discovery pipeline to crawl about 200k polar specific documents from the scientific web, within a day.

  13. Domain shape instabilities and dendrite domain growth in uniaxial ferroelectrics

    Science.gov (United States)

    Shur, Vladimir Ya.; Akhmatkhanov, Andrey R.

    2018-01-01

    The effects of domain wall shape instabilities and the formation of nanodomains in front of moving walls obtained in various uniaxial ferroelectrics are discussed. Special attention is paid to the formation of self-assembled nanoscale and dendrite domain structures under highly non-equilibrium switching conditions. All obtained results are considered in the framework of the unified kinetic approach to domain structure evolution based on the analogy with first-order phase transformation. This article is part of the theme issue `From atomistic interfaces to dendritic patterns'.

  14. Separated matter and antimatter domains with vanishing domain walls

    Energy Technology Data Exchange (ETDEWEB)

    Dolgov, A.D.; Godunov, S.I.; Rudenko, A.S.; Tkachev, I.I., E-mail: dolgov@fe.infn.it, E-mail: sgodunov@itep.ru, E-mail: a.s.rudenko@inp.nsk.su, E-mail: tkachev@ms2.inr.ac.ru [Physics Department and Laboratory of Cosmology and Elementary Particle Physics, Novosibirsk State University, Pirogova st. 2, Novosibirsk, 630090 (Russian Federation)

    2015-10-01

    We present a model of spontaneous (or dynamical) C and CP violation where it is possible to generate domains of matter and antimatter separated by cosmologically large distances. Such C(CP) violation existed only in the early universe and later it disappeared with the only trace of generated baryonic and/or antibaryonic domains. So the problem of domain walls in this model does not exist. These features are achieved through a postulated form of interaction between inflaton and a new scalar field, realizing short time C(CP) violation.

  15. From scenarios to domain models: processes and representations

    Science.gov (United States)

    Haddock, Gail; Harbison, Karan

    1994-03-01

    The domain specific software architectures (DSSA) community has defined a philosophy for the development of complex systems. This philosophy improves productivity and efficiency by increasing the user's role in the definition of requirements, increasing the systems engineer's role in the reuse of components, and decreasing the software engineer's role to the development of new components and component modifications only. The scenario-based engineering process (SEP), the first instantiation of the DSSA philosophy, has been adopted by the next generation controller project. It is also the chosen methodology of the trauma care information management system project, and the surrogate semi-autonomous vehicle project. SEP uses scenarios from the user to create domain models and define the system's requirements. Domain knowledge is obtained from a variety of sources including experts, documents, and videos. This knowledge is analyzed using three techniques: scenario analysis, task analysis, and object-oriented analysis. Scenario analysis results in formal representations of selected scenarios. Task analysis of the scenario representations results in descriptions of tasks necessary for object-oriented analysis and also subtasks necessary for functional system analysis. Object-oriented analysis of task descriptions produces domain models and system requirements. This paper examines the representations that support the DSSA philosophy, including reference requirements, reference architectures, and domain models. The processes used to create and use the representations are explained through use of the scenario-based engineering process. Selected examples are taken from the next generation controller project.

  16. Impedance measurements of components for the ALS

    International Nuclear Information System (INIS)

    Corlett, J.N.; Rimmer, R.A.

    1993-05-01

    The high current and short bunch length of the ALS beam make the machine susceptible to beam instabilities over a frequency range extending to 13 GHz and beyond. All components of the storage ring have been carefully designed to minimize the impedance presented to the beam, and assemblies have been laid out to avoid resonant enclosures between components. Novel bellows shields allowing considerable mechanical movement while maintaining a low impedance are described. Results are presented of impedance measurements of ALS components and assemblies of components, using a precision coaxial wire technique in frequency domain, extending to frequencies beyond cut-off. All measurements were performed at the Lambertson Beam Electrodynamics Laboratory of the Center for Beam Physics at LBL

  17. Bioethics for Technical Experts

    Science.gov (United States)

    Asano, Shigetaka

    Along with rapidly expanding applications of life science and technology, technical experts have been implicated more and more often with ethical, social, and legal problems than before. It should be noted that in this background there are scientific and social uncertainty elements which are inevitable during the progress of life science in addition to the historically-established social unreliability to scientists and engineers. In order to solve these problems, therefore, we should establish the social governance with ‘relief’ and ‘reliance’ which enables for both citizens and engineers to share the awareness of the issues, to design social orders and criterions based on hypothetical sense of values for bioethics, to carry out practical use management of each subject carefully, and to improve the sense of values from hypothetical to universal. Concerning these measures, the technical experts can learn many things from the present performance in the medical field.

  18. Sources of technical assistance

    International Nuclear Information System (INIS)

    Laue, H.J.

    1977-01-01

    This paper shows examples of technical assistance programmes within bilateral cooperation agreements between the Federal Republic of Germany and a number of developing countries of very different characteristics and summarizes the possibilities of technical assistance granted by international organizations, such as IAEA, UNDP, etc. A basic requirement for a successful transfer of technology is a high knowledge level of the indigenous scientists and engineers. Therefore, programmes for training and education and for information exchange are presented. Based on these, the means and methods of planning, performance and quality assurance are explained by practical examples and are related to the progress achieved in the use of nuclear energy and in establishing a national industry in the developing countries. (orig.) [de

  19. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: The Joint PVSS JCOP Framework: 14 - 18.6.2004 (5 days) EXCEL 2003 - niveau 2 : 17 & 18.6.2004 (2 jours) MAGNE-04 : Magnétisme pour l'électrotechnique : 6 au 8.7.2004 (3 jours) Technical Training Monique Duval - Tel.74924 technical.training@cern.ch

  20. Understanding Socio Technical Modularity

    DEFF Research Database (Denmark)

    Thuesen, Christian Langhoff; Kudsk, Anders; Hvam, Lars

    2011-01-01

    Modularity has gained an increasing popularity as a central concept for exploring product structure, process structure, organization structure and supply chain structure. With the offset in system theory the predominant understanding of modularity however faces difficulties in explaining the social...... dimension of modularity like irrational behaviors, cultural differences, learning processes, social organization and institutional influences on modularity. The paper addresses this gab offering a reinterpretation of the modularity concept from a socio-technical perspective in general and Actor Network...... Theory in particular. By formulating modularity from an ANT perspective covering social, material and process aspects, the modularity of a socio-technical system can be understood as an entanglement of product, process, organizational and institutional modularity. The theoretical framework is illustrated...

  1. Independent technical review, handbook

    International Nuclear Information System (INIS)

    1994-02-01

    Purpose Provide an independent engineering review of the major projects being funded by the Department of Energy, Office of Environmental Restoration and Waste Management. The independent engineering review will address questions of whether the engineering practice is sufficiently developed to a point where a major project can be executed without significant technical problems. The independent review will focus on questions related to: (1) Adequacy of development of the technical base of understanding; (2) Status of development and availability of technology among the various alternatives; (3) Status and availability of the industrial infrastructure to support project design, equipment fabrication, facility construction, and process and program/project operation; (4) Adequacy of the design effort to provide a sound foundation to support execution of project; (5) Ability of the organization to fully integrate the system, and direct, manage, and control the execution of a complex major project

  2. Independent technical review, handbook

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    Purpose Provide an independent engineering review of the major projects being funded by the Department of Energy, Office of Environmental Restoration and Waste Management. The independent engineering review will address questions of whether the engineering practice is sufficiently developed to a point where a major project can be executed without significant technical problems. The independent review will focus on questions related to: (1) Adequacy of development of the technical base of understanding; (2) Status of development and availability of technology among the various alternatives; (3) Status and availability of the industrial infrastructure to support project design, equipment fabrication, facility construction, and process and program/project operation; (4) Adequacy of the design effort to provide a sound foundation to support execution of project; (5) Ability of the organization to fully integrate the system, and direct, manage, and control the execution of a complex major project.

  3. Durability of building materials and components

    CERN Document Server

    Delgado, JMPQ

    2013-01-01

    Durability of Building Materials and Components provides a collection of recent research works to contribute to the systematization and dissemination of knowledge related to the long-term performance and durability of construction and, simultaneously, to show the most recent advances in this domain. It includes a set of new developments in the field of durability, service life prediction methodologies, the durability approach for historical and old buildings, asset and maintenance management and on the durability of materials, systems and components. The book is divided in several chapters that intend to be a resume of the current state of knowledge for benefit of professional colleagues.

  4. Technical approach document

    International Nuclear Information System (INIS)

    1989-12-01

    The Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978, Public Law 95-604 (PL95-604), grants the Secretary of Energy the authority and responsibility to perform such actions as are necessary to minimize radiation health hazards and other environmental hazards caused by inactive uranium mill sites. This Technical Approach Document (TAD) describes the general technical approaches and design criteria adopted by the US Department of Energy (DOE) in order to implement remedial action plans (RAPS) and final designs that comply with EPA standards. It does not address the technical approaches necessary for aquifer restoration at processing sites; a guidance document, currently in preparation, will describe aquifer restoration concerns and technical protocols. This document is a second revision to the original document issued in May 1986; the revision has been made in response to changes to the groundwater standards of 40 CFR 192, Subparts A--C, proposed by EPA as draft standards. New sections were added to define the design approaches and designs necessary to comply with the groundwater standards. These new sections are in addition to changes made throughout the document to reflect current procedures, especially in cover design, water resources protection, and alternate site selection; only minor revisions were made to some of the sections. Sections 3.0 is a new section defining the approach taken in the design of disposal cells; Section 4.0 has been revised to include design of vegetated covers; Section 8.0 discusses design approaches necessary for compliance with the groundwater standards; and Section 9.0 is a new section dealing with nonradiological hazardous constituents. 203 refs., 18 figs., 26 tabs

  5. Technical Leadership Development Program

    Science.gov (United States)

    2010-12-13

    the traditional tenets of leadership and management , systems thinking, understanding SOS issues, and thinking and acting holistically. Our research...international element 2.0 Enterprise Leadership and Management UNCLASSIFIED Contract Number: H98230-08-D-0171 DO 002. TO002, RT 004 Report No...mechanisms for leadership of the overall technical effort, for systems engineering, for requirements, management , and for systems integration. o Develop

  6. Technical issues for WIPP

    International Nuclear Information System (INIS)

    Hunter, T.O.

    1979-01-01

    Emplacement of wastes in the WIPP will include experiments on various waste types which will provide essential data on waste-rock interaction and repository response. These experiments will include evolution of the synergistic effects of both heat production, radiation, and actual waste forms. While these studies will provide essential data on the validity of waste isolation in bedded salt, they will be preceded by a broad-based experimental program which will resolve many of the current technical issues providing not only an assessment of the safety of performing such experiments but also the technical basis for assurance that the appropriate experiments are performed. Data and predictive modeling techniques, which are currently available, can bound the consequences associated with these technical issues. Predictions of the impact on public safety based on these analyses indicate that safe waste disposal in WIPP salt beds is achievable; however, a major use of WIPP will be to conduct realistic experiments with HLW forms to address some of the unresolved details of these waste/salt interactions

  7. Technical training - Places available

    CERN Multimedia

    2012-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924) HR Department Electronic Design Next Session Duration Language Availability Comprehensive VHDL for FPGA Design 08-Oct-12 to 12-Oct-12 5 days English 4 places Electrostatique / Protection ESD 28-Sep-12 to 28-Sep-12 3 hours French 25 places Impacts de la suppression du plomb (RoHS) en électronique 26-Oct-12 to 26-Oct-12 8 hours French 14 places Introduction to VHDL 10-Oct-12 to 11-Oct-12 2 days English 9 places LabVIEW Real Time and FPGA 13-Nov-12 to 16-Nov-12 5 days French 5 places LabVIEW for Experts 24-Sep-12 to 28-Sep-12 5 days English 6 places LabVIEW for beginners 15-Oct-12 to 17-...

  8. Technical Assistance Needs Assessments (TANAs)

    Science.gov (United States)

    The Technical Assistance Needs Assessment (TANA) is a process to identify whether a community requires additional support from EPA in order to understand technical information and have meaningful participation in the Superfund decision-making process.

  9. El Salvador - Formal Technical Education

    Data.gov (United States)

    Millennium Challenge Corporation — With a budget of nearly $20 million, the Formal Technical Education Sub-Activity was designed to strengthen technical and vocational educational institutions in the...

  10. Risk management through dynamic technical specifications

    International Nuclear Information System (INIS)

    Klopp, George T.; Petersen, Thomas A.

    2004-01-01

    The wide deployment of plant specific probabilistic risk assessments for nuclear power plants has provided the means to effect a fresh risk management perspective and a fresh, risk based, regulatory outlook on nuclear power. There has been a great deal of conversation on risk based regulation within the U. S. nuclear power industry but, curiously, very little on effective risk management. This paper proposes a means to link the two subjects through the plant Technical Specifications. A revised concept for Technical Specifications is suggested which is based on deterministic analyses and probabilistic risk assessments for each plant. The revised Technical Specifications would consider, on a real-time basis, the exact state of the plant in terms of the status of key components and systems. It would depict current plant risk levels and compare those levels to the desired and limiting (alert/action) levels. It would advise the plant operator on the risk impact of proposed actions through a simple query system and illustrate the impact of such actions on plant status relative to designated risk values. The basis for the proposed approach lies in realistic deterministic plant analyses and probabilistic risk assessment (PRA) deployment tools being developed, in parallel, by a number of parties in the U.S. today. These PRAs are based primarily on the existing plant responses to Generic Letter 88-20, 'Individual Plant Examinations' (IPEs). Each of these tools allows the plant operator to input, on a real-time basis, the status of key equipment and systems. The tools then provide explicit illustrations of dependency effects; updated, 'real-time' risk status indications such as core damage frequency; and, in some cases, allow the operator to assess the risk impact of removing from service selected components for maintenance or testing. These systems generally operate on personal computers and provide nearly instantaneous responses to plant queries. Moving from these tools to

  11. CEEM Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Bowers, John [Univ. of California, Santa Barbara, CA (United States)

    2014-11-26

    reactions that produce them. In response, the CEEM team developed well-defined molecular semiconductors that produce active layers with very high power conversion efficiencies, in other words they can convert a very high fraction of sunlight into useful electrical power. The fact that the semiconductor is formed from molecular species provides the basis for circumventing the unreliability of polymer counterparts and, as an additional bonus, allows one to attain much grater insight into the structure of the active layer. The latter is particularly important because efficient conversion is the result of a complex arrangement of two semiconductors that need to phase separate in a way akin to oil and water, but with domains that are described by nanoscale dimensions. CEEM was therefore able to provide deep insight into the influence of nanostructure, through the application of structural characterization tools and theoretical methods that describe how electrical charges migrate through the organic layer. Our research in light emitting diode (LED)-based solid state lighting (SSL) was directed at improving efficiency and reducing costs to enable the widespread deployment of economically-viable replacements for inefficient incandescent, halogen, and fluorescent-based lighting. Our specific focus was to advance the fundamental science and technology of light emitting diodes to both understand factors that limit efficiencies and to provide innovative and viable solutions to the current impediments. One of the main challenges we faced is the decrease in efficiency when LEDs are driven harder to increase light output---the so called “droop” effect. It requires large emitting surfaces to reach a desired optical output, and necessitates the use of costly heat sinks, both of which increase the cost. We successfully reduced droop by growing LED crystals having non-conventional orientations. As recognized by the award of the 2014 Nobel prize to the inventors of the nitride LEDs (one of

  12. Ferroelectric negative capacitance domain dynamics

    Science.gov (United States)

    Hoffmann, Michael; Khan, Asif Islam; Serrao, Claudy; Lu, Zhongyuan; Salahuddin, Sayeef; Pešić, Milan; Slesazeck, Stefan; Schroeder, Uwe; Mikolajick, Thomas

    2018-05-01

    Transient negative capacitance effects in epitaxial ferroelectric Pb(Zr0.2Ti0.8)O3 capacitors are investigated with a focus on the dynamical switching behavior governed by domain nucleation and growth. Voltage pulses are applied to a series connection of the ferroelectric capacitor and a resistor to directly measure the ferroelectric negative capacitance during switching. A time-dependent Ginzburg-Landau approach is used to investigate the underlying domain dynamics. The transient negative capacitance is shown to originate from reverse domain nucleation and unrestricted domain growth. However, with the onset of domain coalescence, the capacitance becomes positive again. The persistence of the negative capacitance state is therefore limited by the speed of domain wall motion. By changing the applied electric field, capacitor area or external resistance, this domain wall velocity can be varied predictably over several orders of magnitude. Additionally, detailed insights into the intrinsic material properties of the ferroelectric are obtainable through these measurements. A new method for reliable extraction of the average negative capacitance of the ferroelectric is presented. Furthermore, a simple analytical model is developed, which accurately describes the negative capacitance transient time as a function of the material properties and the experimental boundary conditions.

  13. Stochastic lattice model of synaptic membrane protein domains.

    Science.gov (United States)

    Li, Yiwei; Kahraman, Osman; Haselwandter, Christoph A

    2017-05-01

    Neurotransmitter receptor molecules, concentrated in synaptic membrane domains along with scaffolds and other kinds of proteins, are crucial for signal transmission across chemical synapses. In common with other membrane protein domains, synaptic domains are characterized by low protein copy numbers and protein crowding, with rapid stochastic turnover of individual molecules. We study here in detail a stochastic lattice model of the receptor-scaffold reaction-diffusion dynamics at synaptic domains that was found previously to capture, at the mean-field level, the self-assembly, stability, and characteristic size of synaptic domains observed in experiments. We show that our stochastic lattice model yields quantitative agreement with mean-field models of nonlinear diffusion in crowded membranes. Through a combination of analytic and numerical solutions of the master equation governing the reaction dynamics at synaptic domains, together with kinetic Monte Carlo simulations, we find substantial discrepancies between mean-field and stochastic models for the reaction dynamics at synaptic domains. Based on the reaction and diffusion properties of synaptic receptors and scaffolds suggested by previous experiments and mean-field calculations, we show that the stochastic reaction-diffusion dynamics of synaptic receptors and scaffolds provide a simple physical mechanism for collective fluctuations in synaptic domains, the molecular turnover observed at synaptic domains, key features of the observed single-molecule trajectories, and spatial heterogeneity in the effective rates at which receptors and scaffolds are recycled at the cell membrane. Our work sheds light on the physical mechanisms and principles linking the collective properties of membrane protein domains to the stochastic dynamics that rule their molecular components.

  14. Macroscopic domain formation in the platelet plasma membrane

    DEFF Research Database (Denmark)

    Bali, Rachna; Savino, Laura; Ramirez, Diego A.

    2009-01-01

    There has been ample debate on whether cell membranes can present macroscopic lipid domains as predicted by three-component phase diagrams obtained by fluorescence microscopy. Several groups have argued that membrane proteins and interactions with the cytoskeleton inhibit the formation of large d...

  15. Purification of SOCS (Suppressor of Cytokine Signaling) SH2 Domains for Structural and Functional Studies.

    Science.gov (United States)

    Liau, Nicholas P D; Laktyushin, Artem; Babon, Jeffrey J

    2017-01-01

    Src Homology 2 (SH2) domains are protein domains which have a high binding affinity for specific amino acid sequences containing a phosphorylated tyrosine residue. The Suppressors of Cytokine Signaling (SOCS) proteins use an SH2 domain to bind to components of certain cytokine signaling pathways to downregulate the signaling cascade. The recombinantly produced SH2 domains of various SOCS proteins have been used to undertake structural and functional studies elucidating the method of how such targeting occurs. Here, we describe the protocol for the recombinant production and purification of SOCS SH2 domains, with an emphasis on SOCS3.

  16. Assessing Students' Technical Skill Attainment

    Science.gov (United States)

    Jorgensen, Haley

    2010-01-01

    The Wisconsin Technical College System (WTCS) is working to comply with the Carl D. Perkins Career and Technical Education Improvement Act of 2006 (Perkins) to ensure that its graduates have mastered the technical skills needed by business and industry. The legislation requires that each state identify and approve program assessment strategies…

  17. Components of Adenovirus Genome Packaging

    Science.gov (United States)

    Ahi, Yadvinder S.; Mittal, Suresh K.

    2016-01-01

    Adenoviruses (AdVs) are icosahedral viruses with double-stranded DNA (dsDNA) genomes. Genome packaging in AdV is thought to be similar to that seen in dsDNA containing icosahedral bacteriophages and herpesviruses. Specific recognition of the AdV genome is mediated by a packaging domain located close to the left end of the viral genome and is mediated by the viral packaging machinery. Our understanding of the role of various components of the viral packaging machinery in AdV genome packaging has greatly advanced in recent years. Characterization of empty capsids assembled in the absence of one or more components involved in packaging, identification of the unique vertex, and demonstration of the role of IVa2, the putative packaging ATPase, in genome packaging have provided compelling evidence that AdVs follow a sequential assembly pathway. This review provides a detailed discussion on the functions of the various viral and cellular factors involved in AdV genome packaging. We conclude by briefly discussing the roles of the empty capsids, assembly intermediates, scaffolding proteins, portal vertex and DNA encapsidating enzymes in AdV assembly and packaging. PMID:27721809

  18. Supply chain components

    OpenAIRE

    Vieraşu, T.; Bălăşescu, M.

    2011-01-01

    In this article I will go through three main logistics components, which are represented by: transportation, inventory and facilities, and the three secondary logistical components: information, production location, price and how they determine performance of any supply chain. I will discuss then how these components are used in the design, planning and operation of a supply chain. I will also talk about some obstacles a supply chain manager may encounter.

  19. Supply chain components

    Directory of Open Access Journals (Sweden)

    Vieraşu, T.

    2011-01-01

    Full Text Available In this article I will go through three main logistics components, which are represented by: transportation, inventory and facilities, and the three secondary logistical components: information, production location, price and how they determine performance of any supply chain. I will discuss then how these components are used in the design, planning and operation of a supply chain. I will also talk about some obstacles a supply chain manager may encounter.

  20. Control component retainer

    International Nuclear Information System (INIS)

    Walton, L.A.; King, R.A.

    1983-01-01

    An apparatus is described for retaining an undriven control component assembly disposed in a fuel assembly in a nuclear reactor of the type having a core grid plate. The first part of the mechanism involves a housing for the control component and the second part is a brace with a number of arms that reach under the grid plate. The brace and the housing are coupled together to firmly hold the control components in place even under strong flows of th coolant

  1. Wavefield extrapolation in pseudodepth domain

    KAUST Repository

    Ma, Xuxin

    2013-02-01

    Wavefields are commonly computed in the Cartesian coordinate frame. Its efficiency is inherently limited due to spatial oversampling in deep layers, where the velocity is high and wavelengths are long. To alleviate this computational waste due to uneven wavelength sampling, we convert the vertical axis of the conventional domain from depth to vertical time or pseudodepth. This creates a nonorthognal Riemannian coordinate system. Isotropic and anisotropic wavefields can be extrapolated in the new coordinate frame with improved efficiency and good consistency with Cartesian domain extrapolation results. Prestack depth migrations are also evaluated based on the wavefield extrapolation in the pseudodepth domain.© 2013 Society of Exploration Geophysicists. All rights reserved.

  2. Component design for LMFBR's

    International Nuclear Information System (INIS)

    Fillnow, R.H.; France, L.L.; Zerinvary, M.C.; Fox, R.O.

    1975-01-01

    Just as FFTF has prototype components to confirm their design, FFTF is serving as a prototype for the design of the commercial LMFBR's. Design and manufacture of critical components for the FFTF system have been accomplished primarily using vendors with little or no previous experience in supplying components for high temperature sodium systems. The exposure of these suppliers, and through them a multitude of subcontractors, to the requirements of this program has been a necessary and significant step in preparing American industry for the task of supplying the large mechanical components required for commercial LMFBR's

  3. Hot gas path component

    Science.gov (United States)

    Lacy, Benjamin Paul; Kottilingam, Srikanth Chandrudu; Porter, Christopher Donald; Schick, David Edward

    2017-09-12

    Various embodiments of the disclosure include a turbomachine component. and methods of forming such a component. Some embodiments include a turbomachine component including: a first portion including at least one of a stainless steel or an alloy steel; and a second portion joined with the first portion, the second portion including a nickel alloy including an arced cooling feature extending therethrough, the second portion having a thermal expansion coefficient substantially similar to a thermal expansion coefficient of the first portion, wherein the arced cooling feature is located within the second portion to direct a portion of a coolant to a leakage area of the turbomachine component.

  4. Simulation research to enhance patient safety and outcomes: recommendations of the Simnovate Patient Safety Domain Group

    OpenAIRE

    Pucher, PH; Tamblyn, R; Boorman, D; Dixon-Woods, Mary Margaret; Donaldson, L; Draycott, T; Forster, A; Nadkarni, V; Power, C; Sevdalis, N; Aggarwal, R

    2017-01-01

    The use of simulation-based training has established itself in healthcare but its implementation has been varied and mostly limited to technical and non-technical skills training. This article discusses the possibilities of the use of simulation as part of an overarching approach to improving patient safety, and represents the views of the Simnovate Patient Safety Domain Group, an international multidisciplinary expert group dedicated to the improvement of patient safety. The application and ...

  5. Final Technical Report

    International Nuclear Information System (INIS)

    Diedhiou, Papa Madiallacke

    2010-01-01

    The established training programme, covering three months is structured over 2 main components: 1. Induced mutagenesis for the genetic improvement of Jatropha; 2. Genotyping using molecular markers in order to link phenotypic diversity to genotype.

  6. Domain decomposition methods for the neutron diffusion problem

    International Nuclear Information System (INIS)

    Guerin, P.; Baudron, A. M.; Lautard, J. J.

    2010-01-01

    The neutronic simulation of a nuclear reactor core is performed using the neutron transport equation, and leads to an eigenvalue problem in the steady-state case. Among the deterministic resolution methods, simplified transport (SPN) or diffusion approximations are often used. The MINOS solver developed at CEA Saclay uses a mixed dual finite element method for the resolution of these problems. and has shown his efficiency. In order to take into account the heterogeneities of the geometry, a very fine mesh is generally required, and leads to expensive calculations for industrial applications. In order to take advantage of parallel computers, and to reduce the computing time and the local memory requirement, we propose here two domain decomposition methods based on the MINOS solver. The first approach is a component mode synthesis method on overlapping sub-domains: several Eigenmodes solutions of a local problem on each sub-domain are taken as basis functions used for the resolution of the global problem on the whole domain. The second approach is an iterative method based on a non-overlapping domain decomposition with Robin interface conditions. At each iteration, we solve the problem on each sub-domain with the interface conditions given by the solutions on the adjacent sub-domains estimated at the previous iteration. Numerical results on parallel computers are presented for the diffusion model on realistic 2D and 3D cores. (authors)

  7. Organization Domain Modeling. Volume 1. Conceptual Foundations, Process and Workproduct Description

    Science.gov (United States)

    1993-07-31

    Analysis Companies must often analyze their software products or services relative to those of competitors in the marketplace to determine issues such as...J.A. Hess, W.E. Novak, and A.S. Peterson. Feature-Oriented Domain Analysis ( FODA ) Feasibility Study. Technical Report CMU/SEI-90-TR-21, Software...domain analysis (DA) and modeling, including a structured set of workproducts, a tailorable process model and a set of modeling techniques and guidelines

  8. Towards technical interoperability in telemedicine.

    Energy Technology Data Exchange (ETDEWEB)

    Craft, Richard Layne, II

    2004-05-01

    For telemedicine to realize the vision of anywhere, anytime access to care, the question of how to create a fully interoperable technical infrastructure must be addressed. After briefly discussing how 'technical interoperability' compares with other types of interoperability being addressed in the telemedicine community today, this paper describes reasons for pursuing technical interoperability, presents a proposed framework for realizing technical interoperability, identifies key issues that will need to be addressed if technical interoperability is to be achieved, and suggests a course of action that the telemedicine community might follow to accomplish this goal.

  9. Topology Based Domain Search (TBDS)

    National Research Council Canada - National Science Library

    Manning, William

    2002-01-01

    This effort will explore radical changes in the way Domain Name System (DNS) is used by endpoints in a network to improve the resilience of the endpoint and its applications in the face of dynamically changing infrastructure topology...

  10. Domain Discretization and Circle Packings

    DEFF Research Database (Denmark)

    Dias, Kealey

    A circle packing is a configuration of circles which are tangent with one another in a prescribed pattern determined by a combinatorial triangulation, where the configuration fills a planar domain or a two-dimensional surface. The vertices in the triangulation correspond to centers of circles...... to domain discretization problems such as triangulation and unstructured mesh generation techniques. We wish to ask ourselves the question: given a cloud of points in the plane (we restrict ourselves to planar domains), is it possible to construct a circle packing preserving the positions of the vertices...... and constrained meshes having predefined vertices as constraints. A standard method of two-dimensional mesh generation involves conformal mapping of the surface or domain to standardized shapes, such as a disk. Since circle packing is a new technique for constructing discrete conformal mappings, it is possible...

  11. Heliborne time domain electromagnetic system

    International Nuclear Information System (INIS)

    Bhattacharya, S.

    2009-01-01

    Atomic Minerals Directorate (AMD), are using heliborne and ground time domain electromagnetic (TDEM) system for the exploration of deep seated unconformity type uranium deposits. Uranium has been explored in various parts of the world like Athabasca basin using time domain electromagnetic system. AMD has identified some areas in India where such deposits are available. Apart from uranium exploration, the TDEM systems are used for the exploration of deep seated minerals like diamonds. Bhabha Atomic Research Centre (BARC) is involved in the indigenous design of the heliborne time domain system since this system is useful for DAE and also it has a scope of wide application. In this paper we discuss about the principle of time domain electromagnetic systems, their capabilities and the development and problems of such system for various other mineral exploration. (author)

  12. Anisotropy of domain wall resistance

    Science.gov (United States)

    Viret; Samson; Warin; Marty; Ott; Sondergard; Klein; Fermon

    2000-10-30

    The resistive effect of domain walls in FePd films with perpendicular anisotropy was studied experimentally as a function of field and temperature. The films were grown directly on MgO substrates, which induces an unusual virgin magnetic configuration composed of 60 nm wide parallel stripe domains. This allowed us to carry out the first measurements of the anisotropy of domain wall resistivity in the two configurations of current perpendicular and parallel to the walls. At 18 K, we find 8.2% and 1.3% for the domain wall magnetoresistance normalized to the wall width (8 nm) in these two respective configurations. These values are consistent with the predictions of Levy and Zhang.

  13. Facilitating Inter-Domain Synergies in Ambient Assisted Living Environments.

    Science.gov (United States)

    Schwartze, Jonas; Schrom, Harald; Wolf, Klaus-Hendrik; Marschollek, Michael

    2016-01-01

    Current Ambient Assisted Living (AAL) environments lack integration of sensors and actuators of other sub-domains. Creating technical and organizational integration is addressed by the BASIS project (Build Automation by a Scalable and Intelligent System), which aims to build a cross-domain home bus system. The main objective of this paper is to present an overview of design, architecture and state of realization of BASIS by describing the requirements development process, underlying hardware design and software architecture. We built a distributed system of one independent building manager with several redundantly meshed segment controllers, each controlling a bus segment with any number of bus nodes. The software system layer is divided into logical partitions representing each sub-domain. Structured data storage is possible with a special FHIR based home centered data warehouse. The system has been implemented in six apartments running under daily living conditions. BASIS integrates a broad range of sub-domains, which poses challenges to all project partners in terms of a common terminology, and project management methods, but enables development of inter-domain synergies like using the same sensor and actuator hardware for a broad range of services and use cases.

  14. Components of Sexual Identity

    Science.gov (United States)

    Shively, Michael G.; DeCecco, John P.

    1977-01-01

    This paper examines the four components of sexual identity: biological sex, gender identity, social sex-role, and sexual orientation. Theories about the development of each component and how they combine and conflict to form the individual's sexual identity are discussed. (Author)

  15. Towards Cognitive Component Analysis

    DEFF Research Database (Denmark)

    Hansen, Lars Kai; Ahrendt, Peter; Larsen, Jan

    2005-01-01

    Cognitive component analysis (COCA) is here defined as the process of unsupervised grouping of data such that the ensuing group structure is well-aligned with that resulting from human cognitive activity. We have earlier demonstrated that independent components analysis is relevant for representing...

  16. Maneuver from the Air Domain

    Science.gov (United States)

    2016-05-26

    Overload From the previous discussion, cognitive maneuver seeks to degrade the enemy’s capacity for...in all domains, the ability to maneuver from the air domain in the cognitive sense, comes primarily from air power’s unique ability to overload the... cognitive maneuver mechanisms developed in the 1980s as part of broader maneuver warfare theory. The result is a proposed definition of maneuver from

  17. Ferroelectric Negative Capacitance Domain Dynamics

    OpenAIRE

    Hoffmann, Michael; Khan, Asif Islam; Serrao, Claudy; Lu, Zhongyuan; Salahuddin, Sayeef; Pešić, Milan; Slesazeck, Stefan; Schroeder, Uwe; Mikolajick, Thomas

    2017-01-01

    Transient negative capacitance effects in epitaxial ferroelectric Pb(Zr$_{0.2}$Ti$_{0.8}$)O$_3$ capacitors are investigated with a focus on the dynamical switching behavior governed by domain nucleation and growth. Voltage pulses are applied to a series connection of the ferroelectric capacitor and a resistor to directly measure the ferroelectric negative capacitance during switching. A time-dependent Ginzburg-Landau approach is used to investigate the underlying domain dynamics. The transien...

  18. Gravity and domain wall problem

    International Nuclear Information System (INIS)

    Rai, B.; Senjanovic, G.

    1992-11-01

    It is well known that the spontaneous breaking of discrete symmetries may lead to conflict with big-bang cosmology. This is due to formation of domain walls which give unacceptable contribution to the energy density of the universe. On the other hand, it is expected that gravity breaks global symmetries explicitly. In this work we propose that this could provide a natural solution to the domain-wall problem. (author). 17 refs

  19. Incompleteness in the finite domain

    Czech Academy of Sciences Publication Activity Database

    Pudlák, Pavel

    2017-01-01

    Roč. 23, č. 4 (2017), s. 405-441 ISSN 1079-8986 EU Projects: European Commission(XE) 339691 - FEALORA Institutional support: RVO:67985840 Keywords : finite domain Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 0.742, year: 2016 https://www.cambridge.org/core/journals/bulletin-of-symbolic-logic/article/incompleteness-in-the-finite-domain/D239B1761A73DCA534A4805A76D81C76

  20. Argentina technical report

    International Nuclear Information System (INIS)

    2002-01-01

    At present, the Production Cyclotron Facility, installed at the Ezeiza Atomic Centre, is used for Tl-201 production; F-18 and I-123 production will be incorporated during this year. Concerning I-123 production, a system for irradiation of gaseous target has been developed in the frame of the IAEA Technical Assistance Project (ARG4085). The iodine production system delivers an ultra pure radioisotope via nuclear reactions: 124 Xe (p,2n) 123 Cs → 123 Xe → 123 I and 124 Xe (p,pn) 123 Xe → 123 I. This report describes the target and irradiation chamber design, the radiochemical purification process

  1. Technical Report 2000

    International Nuclear Information System (INIS)

    2001-01-01

    The technical memory 2000 of the Nuclear Regulatory Authority (NRA) of the Argentine Republic, compile the papers published in the subject on radiation protection and nuclear safety, safeguards and physical protection, and presented in congress or meetings of these specialities by personnel of the mentioned institution during 2000. In this edition the documents are presented on: Nuclear safety; Radiobiology; Occupational doses; Radiochemical; Environmental studies; Emergency plans; Radiation accidents; and International safeguards. Some of them are realized by agreements between the Nuclear Regulatory Authority of Argentina, universities and other national and international organizations

  2. HPCG Benchmark Technical Specification

    Energy Technology Data Exchange (ETDEWEB)

    Heroux, Michael Allen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Dongarra, Jack [Univ. of Tennessee, Knoxville, TN (United States); Luszczek, Piotr [Univ. of Tennessee, Knoxville, TN (United States)

    2013-10-01

    The High Performance Conjugate Gradient (HPCG) benchmark [cite SNL, UTK reports] is a tool for ranking computer systems based on a simple additive Schwarz, symmetric Gauss-Seidel preconditioned conjugate gradient solver. HPCG is similar to the High Performance Linpack (HPL), or Top 500, benchmark [1] in its purpose, but HPCG is intended to better represent how today’s applications perform. In this paper we describe the technical details of HPCG: how it is designed and implemented, what code transformations are permitted and how to interpret and report results.

  3. RADTRAN 6 Technical Manual

    Energy Technology Data Exchange (ETDEWEB)

    Weiner, Ruth F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Neuhauser, Karen Sieglinde [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Heames, Terence John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); O' Donnell, Brandon M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Dennis, Matthew L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-01-01

    This Technical Manual contains descriptions of the calculation models and mathematical and numerical methods used in the RADTRAN 6 computer code for transportation risk and consequence assessment. The RADTRAN 6 code combines user-supplied input data with values from an internal library of physical and radiological data to calculate the expected radiological consequences and risks associated with the transportation of radioactive material. Radiological consequences and risks are estimated with numerical models of exposure pathways, receptor populations, package behavior in accidents, and accident severity and probability.

  4. RADTRAN 6 technical manual.

    Energy Technology Data Exchange (ETDEWEB)

    Weiner, Ruth F.; Neuhauser, Karen Sieglinde; Heames, Terence John; O' Donnell, Brandon M.; Dennis, Matthew L.

    2014-01-01

    This Technical Manual contains descriptions of the calculation models and mathematical and numerical methods used in the RADTRAN 6 computer code for transportation risk and consequence assessment. The RADTRAN 6 code combines user-supplied input data with values from an internal library of physical and radiological data to calculate the expected radiological consequences and risks associated with the transportation of radioactive material. Radiological consequences and risks are estimated with numerical models of exposure pathways, receptor populations, package behavior in accidents, and accident severity and probability.

  5. Technics and ethics

    International Nuclear Information System (INIS)

    Budnick, D.; Gemmel, F.

    1981-01-01

    Questions about the sense of life and the responsibility of technology are ethical questions. Young people in our neighbourhood who, compared to some time ago, see, hear and read much more of the world, deal with them increasingly. However, the permanent stream of information does not at all facilitate orientation but prevents many people from gaining some clearness about their own point of view. In asking the questions: where are we today. How can we get on. How can we start. The relation between ethics and technics is discussed under various aspects. (orig./HSCH) [de

  6. EH domain of EHD1

    Energy Technology Data Exchange (ETDEWEB)

    Kieken, Fabien; Jovic, Marko; Naslavsky, Naava; Caplan, Steve, E-mail: scaplan@unmc.edu; Sorgen, Paul L. [University of Nebraska Medical Center, Department of Biochemistry and Molecular Biology and Eppley Cancer Center (United States)], E-mail: psorgen@unmc.edu

    2007-12-15

    EHD1 is a member of the mammalian C-terminal Eps15 homology domain (EH) containing protein family, and regulates the recycling of various receptors from the endocytic recycling compartment to the plasma membrane. The EH domain of EHD1 binds to proteins containing either an Asn-Pro-Phe or Asp-Pro-Phe motif, and plays an important role in the subcellular localization and function of EHD1. Thus far, the structures of five N-terminal EH domains from other proteins have been solved, but to date, the structure of the EH domains from the four C-terminal EHD family paralogs remains unknown. In this study, we have assigned the 133 C-terminal residues of EHD1, which includes the EH domain, and solved its solution structure. While the overall structure resembles that of the second of the three N-terminal Eps15 EH domains, potentially significant differences in surface charge and the structure of the tripeptide-binding pocket are discussed.

  7. EH domain of EHD1

    International Nuclear Information System (INIS)

    Kieken, Fabien; Jovic, Marko; Naslavsky, Naava; Caplan, Steve; Sorgen, Paul L.

    2007-01-01

    EHD1 is a member of the mammalian C-terminal Eps15 homology domain (EH) containing protein family, and regulates the recycling of various receptors from the endocytic recycling compartment to the plasma membrane. The EH domain of EHD1 binds to proteins containing either an Asn-Pro-Phe or Asp-Pro-Phe motif, and plays an important role in the subcellular localization and function of EHD1. Thus far, the structures of five N-terminal EH domains from other proteins have been solved, but to date, the structure of the EH domains from the four C-terminal EHD family paralogs remains unknown. In this study, we have assigned the 133 C-terminal residues of EHD1, which includes the EH domain, and solved its solution structure. While the overall structure resembles that of the second of the three N-terminal Eps15 EH domains, potentially significant differences in surface charge and the structure of the tripeptide-binding pocket are discussed

  8. TECHNICAL TRAINING SEMINAR: National Instruments

    CERN Multimedia

    Monique Duval

    2004-01-01

    From 9:30 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Data acquisition systems on PCs, industrial measurement and control techniques, advanced LabVIEW software and PXI instrumentation, and system components for tests and automation will be presented. Walk-in courses will address DIAdem, LabVIEW and data acquisition. Language: English and French Free seminars and courses, no registration Organisers: Rolf Stampfli / IT-CO / 78102 & 160367 / Rolf.Stampfli@cern.ch Davide Vitè / HR-PMD-ATT / 75141 Davide.Vite@cern.ch For more information and the complete event programme, please visit the...

  9. Research Institute for Technical Careers

    Science.gov (United States)

    Glenn, Ronald L.

    1996-01-01

    The NASA research grant to Wilberforce University enabled us to establish the Research Institute for Technical Careers (RITC) in order to improve the teaching of science and engineering at Wilberforce. The major components of the research grant are infrastructure development, establishment of the Wilberforce Intensive Summer Experience (WISE), and Joint Research Collaborations with NASA Scientists. (A) Infrastructure Development. The NASA grant has enabled us to improve the standard of our chemistry laboratory and establish the electronics, design, and robotics laboratories. These laboratories have significantly improved the level of instruction at Wilberforce University. (B) Wilberforce Intensive Summer Experience (WISE). The WISE program is a science and engineering bridge program for prefreshman students. It is an intensive academic experience designed to strengthen students' knowledge in mathematics, science, engineering, computing skills, and writing. (C) Joint Collaboration. Another feature of the grant is research collaborations between NASA Scientists and Wilberforce University Scientists. These collaborations have enabled our faculty and students to conduct research at NASA Lewis during the summer and publish research findings in various journals and scientific proceedings.

  10. Overview and status of ITER internal components

    International Nuclear Information System (INIS)

    Merola, Mario; Escourbiac, Frederic; Raffray, René; Chappuis, Philippe; Hirai, Takeshi; Martin, Alex

    2014-01-01

    Highlights: • Manufacturing technologies for the ITER internal components have been developed. • The Blanket System successfully went through its Final Design Review in April 2013. • The decision to start operation with a Divertor with a full-W armour has been taken. - Abstract: The internal components of ITER are one of the most design and technically challenging components of the ITER machine, and include the Blanket System and the Divertor. The Blanket System successfully went through its Final Design Review in April 2013 and now it is entering into the procurement phase. The design and qualification of the Divertor with a full-tungsten armour was successfully completed and this enabled the decision in November 2013 to start operation with this material option. This paper summarizes the engineering design, the R and D, the technology qualification and procurement status of the Blanket System and of the Divertor of the ITER machine

  11. Overview and status of ITER internal components

    Energy Technology Data Exchange (ETDEWEB)

    Merola, Mario, E-mail: mario.merola@iter.org; Escourbiac, Frederic; Raffray, René; Chappuis, Philippe; Hirai, Takeshi; Martin, Alex

    2014-10-15

    Highlights: • Manufacturing technologies for the ITER internal components have been developed. • The Blanket System successfully went through its Final Design Review in April 2013. • The decision to start operation with a Divertor with a full-W armour has been taken. - Abstract: The internal components of ITER are one of the most design and technically challenging components of the ITER machine, and include the Blanket System and the Divertor. The Blanket System successfully went through its Final Design Review in April 2013 and now it is entering into the procurement phase. The design and qualification of the Divertor with a full-tungsten armour was successfully completed and this enabled the decision in November 2013 to start operation with this material option. This paper summarizes the engineering design, the R and D, the technology qualification and procurement status of the Blanket System and of the Divertor of the ITER machine.

  12. Domain-to-domain coupling in voltage-sensing phosphatase.

    Science.gov (United States)

    Sakata, Souhei; Matsuda, Makoto; Kawanabe, Akira; Okamura, Yasushi

    2017-01-01

    Voltage-sensing phosphatase (VSP) consists of a transmembrane voltage sensor and a cytoplasmic enzyme region. The enzyme region contains the phosphatase and C2 domains, is structurally similar to the tumor suppressor phosphatase PTEN, and catalyzes the dephosphorylation of phosphoinositides. The transmembrane voltage sensor is connected to the phosphatase through a short linker region, and phosphatase activity is induced upon membrane depolarization. Although the detailed molecular characteristics of the voltage sensor domain and the enzyme region have been revealed, little is known how these two regions are coupled. In addition, it is important to know whether mechanism for coupling between the voltage sensor domain and downstream effector function is shared among other voltage sensor domain-containing proteins. Recent studies in which specific amino acid sites were genetically labeled using a fluorescent unnatural amino acid have enabled detection of the local structural changes in the cytoplasmic region of Ciona intestinalis VSP that occur with a change in membrane potential. The results of those studies provide novel insight into how the enzyme activity of the cytoplasmic region of VSP is regulated by the voltage sensor domain.

  13. TECHNICAL SUPPORT AS A BASIS OF HIGH AVAILABILITY LEVEL AND IT SYSTEM SERVICE QUALITY

    Directory of Open Access Journals (Sweden)

    Dejan Vidojevic

    2007-06-01

    Full Text Available This work presents the development and implementation methodology of technical support in IT1system operation. Methodology is developed and applied in realistic system (Information system of the Tax administration - DIS 2003, which is technically very complex and highly distributed. The results of IT system availability assessment and identification of the critical components are input parameters in the process of establishing of the technical support. The importance of technical support for achieving optimal IT system availability and IT service quality is assessed according to its operation during one year. The history of technical support system operation is a basis for further continuous improvement.

  14. GMES Space Component: Programme overview

    Science.gov (United States)

    Aschbacher, J.; Milagro-Perez, M. P.

    2012-04-01

    The European Union (EU) and the European Space Agency (ESA) have developed the Global Monitoring for Environment and Security (GMES) programme as Europe's answer to the vital need for joined-up data about our climate, environment and security. Through a unique combination of satellite, atmospheric and Earth-based monitoring systems, the initiative will provide new insight into the state of the land, sea and air, providing policymakers, scientists, businesses and the public with accurate and timely information. GMES capabilities include monitoring and forecasting of climatic change, flood risks, soil and coastal erosion, crop and fish resources, air pollution, greenhouse gases, iceberg distribution and snow cover, among others. To accomplish this, GMES has been divided into three main components: Space, In-situ and Services. The Space Component, led by ESA, comprises five types of new satellites called Sentinels that are being developed by ESA specifically to meet the needs of GMES, the first of which to be launched in 2013. These missions carry a range of technologies, such as radar and multi-spectral imaging instruments for land, ocean and atmospheric monitoring. In addition, access to data from the so-called Contributing Missions guarantees that European space infrastructure is fully used for GMES. An integrated Ground Segment ensures access to Sentinels and Contributing Missions data. The in-situ component, under the coordination of the European Environment Agency (EEA), is composed of atmospheric and Earth based monitoring systems, and based on established networks and programmes at European and international levels. The European Commission is in charge of implementing the services component of GMES and of leading GMES overall. GMES services, fed with data from the Space and In-situ components, will provide essential information in five main domains, atmosphere, ocean and land monitoring as well as emergency response and security. Climate change has been added

  15. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: C++ for Particle Physicists : 8 - 12.3.2004 (6 X 4-hour sessions) Introduction to the CERN EDMS : 9.3.2004 (1 day, free of charge) The EDMS MTF in Practice : 10.3.2004 (morning, free of charge) CLEAN-2002: Working in a Cleanroom : 10.3.2004 (afternoon, free of charge) The CERN EDMS for Engineers : 11.3.2004 (1 day, free of charge) LabVIEW hands-on (E):...

  16. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: LabVIEW base 1 : 25 - 27.2.2004(3 jours) Instructor-led WBTechT study or follow-up for Microsoft applications : 26.2.2004 (morning) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon - free of charge) C++ for Particle Physicists : 8 - 12.3.2004 (6 X 4-hour sessions) LabVIEW hands-on (E) : 16.3.2004 (afternoon) LabVIEW Basics 1 : 22 - 24.3.2004 ...

  17. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Instructor-led WBTechT study for Microsoft applications :12.2.2004 (morning) Instructor-led WBTechT study or follow-up for Microsoft applications : 19.2.2004 (morning) LabVIEW TestStand I (E) : 23 & 24.2.2004 (2 days) LabVIEW base 1 : 25 - 27.2.2004 (3 jours) Instructor-led WBTechT study or follow-up for Microsoft applications : 19.2.2004 (morning) CLEAN-2002 ...

  18. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Instructor-led WBTechT study or follow-up for Microsoft applications : 19.2.2004 (morning) LabVIEW TestStand I (E) : 23 & 24.2.2004 (2 days) LabVIEW base 1 : 25 - 27.2.2004 (3 jours) Instructor-led WBTechT study or follow-up for Microsoft applications : 26.2.2004 (morning) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon - free of charge) C++ for Pa...

  19. Technical training: places available

    CERN Multimedia

    HR Department

    2007-01-01

    CERN Technical Training: Open Courses (April - June 2007) The following course sessions are currently scheduled in the framework of the CERN Technical Training Programme 2007:   AutoCAD 2006 - niveau 1 (course in French): 25.4.- 26.4.2007 & 2.5. - 3.5.2007 (4 days in 2 modules, 5 places available) AutoCAD 2006 - niveau 1 (course in French): 27.6.- 28.6.2007 & 3.7. - 4.7.2007 (4 days in 2 modules, 5 places available) AutoCAD Mechanical 2006 (course in French) 21.6.-22.6.2007 (2 days, 8 places available) * NEW COURSE* Automate de securite S7 (course in French) 14.5.-16.5.2007 (3 days, 4 places available) * NEW COURSE* Automate de securite S7 (course in French): 9.5.-11.5.2007 (3 days, 4 places available) JCOP - Joint PVSS-JCOP Frameswork (course in English): 21.5.-25.5.2007 (5 days, 12 places available) JCOP - Finite State Machines in the JCOP Frameswork (course in English): 12.6.-14.6.2007 (3 days, 12 places available) LabVIEW Basics 1 (in English): 2.-4.5.2007 (3 days, 7 places ...

  20. TECHNICAL TRAINING SEMINAR

    CERN Multimedia

    Davide Vitè

    2002-01-01

    Wednesday 6 March TECHNICAL TRAINING SEMINAR from 9:30 to 16:45 - IT Amphitheatre - bldg. 31.3.004 Analog Devices DSP Day Thorsten Kistler (Application Engineer), Steffen Boerner (Product Specialist) / ANALOG DEVICES Munich Trying to meet your design challenges, Analog Devices compiles application information and offers chipsets, software, reference designs and mixed-signal, application specific DSPs, for a range of real-time signal processing applications. This seminar will present the latest 16bit fixed-point and 32bit floating-point DSPs (roadmaps; internal architectures, blocks, features benchmarks), with their software, development kits and emulators: Fixed-Point DSP-Family, ADSP-218x and ADSP-219x Blackfin DSP SHARC-Family, 2106x and 2116x TigerSHARC Industrial Contact: François Caloz, Sasco-Spoerle GmbH Language: English Free seminar, no registration Organiser: Davide Vitè / HR-TD / 75141 Davide.Vite@cern.ch Please read the full information on the Technical Training Seminars...

  1. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: C++ for Particle Physicists : 8 - 12.3.2004 (6 X 4-hour sessions) Introduction to the CERN EDMS : 9.3.2004 (1 day, free of charge) The EDMS MTF in Practice : 10.3.2004 (morning, free of charge) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon, free of charge) The CERN EDMS for Engineers : 11.3.2004 (1 day, free of charge) LabVIEW...

  2. Technical Training: Places available**

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch ** The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: The JAVA Programming Language Level 1 : 9 & 10.1.2004 (2 days) LabVIEW TestStand I (E) : 23 & 24.2.2004 (2 days) LabVIEW base 1 : 25 - 27.2.2004 (3 jours) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon - free of charge) C++ for Particle Physicists : 8 - 12.3.2004 ( 6 X 4-hour sessions) LabVIEW hands-on (E) 16.3...

  3. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Project Planning with MS-Project :6 & 13.5.2004 (2 days) Word 2003 - niveau 1 : 10 & 11.5.2004 (2 jours) Oracle 9i : SQL : 17 - 19.5.2004 (3 days) Word 2003 - niveau 2 : 24 & 25.5.2004 (2 jours) EXCEL 2003 - niveau 1: 27 & 28.5.2004 (2 jours) STEP7 Programming Level 1 : 1 - 4.6.2004 (4 days) Oracle 9i : Programming with PL/SQL : 2 - 4.6.2...

  4. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: Hands-on Introduction to Python Programming: 28 - 30.6.2005 (3 days) Introduction to ANSYS: 28.6 - 1.7.2005 (4 days) IT3T/3 - Working remotely with Windows XP: 28.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/4 - Editing Websites with Frontpage 2003: 30.6.2005 (IT Technical Training Tutorial, free of charge) LabVIEW base 1 : 4 - 6.7.2005 (3 jours) LabVIEW Basics 2: 7 - 8.7.2005 (2 days) Utilisation des fichiers PDF avec ACROBAT 7.0 : 5.7.2005 (1 jour) FrontPage 2003 - niveau 1 : 6-7.7.2005 (2 jours) WORD 2003 (Short Course I) - HowTo... Work with repetitive tasks /AutoText, AutoFormat, AutoCorrect, Find/Replace) : 4.7.2005 (afternoon) WORD 2003 (Short Course II) - HowTo... Mail merge: 5.7.2005 (afternoon) WORD 2003 (Short Course III) - HowTo... Work with long documents : 6.7.2005 (afternoon) ACCES...

  5. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: Joint PVSS JCOP Framework: 8 - 12.8.2005 (5 days) FrontPage 2003 - niveau 1 : 1 - 2.9.2005 (2 jours) Utilisation des fichiers PDF avec ACROBAT 7.0 : 5.9.2005 (1 jour) LabVIEW Basics 1 : 5 - 7.9.2005 (3 days, dates to be confirmed) Introduction à Windows XP au CERN : 12.9.2005 (1 demi-journée) FrontPage 2003 - niveau 2 : 15 - 16.9.2005 (2 jours) AutoCAD 2005 - niveau 1 : 22, 23, 28, 29.9.2005 (4 jours) MAGNE-05 - Magnétisme pour l'électrotechnique : 27 - 29.9.2005 (3 jours) LabVIEW Application Development (Intermediate I): 5 - 7.12.2005 (3 days) LabVIEW Advanced Programming (Intermediate 2): 8 - 9.12.2005 (2 days) ENSEIGNEMENT TECHNIQUE TECHNICAL TRAINING Monique Duval 74924 technical.training@cern.ch

  6. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: Hands-on Introduction to Python Programming: 28 - 30.6.2005 (3 days) Introduction to ANSYS: 21 - 24.6.2005 (4 days) IT3T/3 - Working remotely with Windows XP: 28.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/4 - Editing Websites with Frontpage 2003: 30.6.2005 (IT Technical Training Tutorial, free of charge) Utilisation des fichiers PDF avec ACROBAT 7.0 : 5.7.2005 (1 jour) FrontPage 2003 - niveau 1 : 6-7.7.2005 (2 jours) LabVIEW base 1 : 4 - 6.7.2005 (3 jours) LabVIEW Basics 2: 7 - 8.7.2005 (2 days) WORD 2003 (Short Course I) - HowTo... Work with repetitive tasks /AutoText, AutoFormat, AutoCorrect, Find/Replace) : 4.7.2005 (afternoon) WORD 2003 (Short Course II) - HowTo... Mail merge: 5.7.2005 (afternoon) WORD 2003 (Short Course III) - HowTo (4 mornings) EXCEL 2003 (Short Course I) - HowTo... Work ...

  7. Technical Training: Places Available

    CERN Multimedia

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. Technical Training Monique Duval - Tel.74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Oracle 9i: SQL: 17 - 19.5.2004 (3 days) Word 2003 - niveau 2 : 24 & 25.5.2004 (2 jours) EXCEL 2003 - niveau 1 : 27 & 28.5.2004 (2 jours) STEP7 Programming Level 1: 1 - 4.6.2004 (4 days) Oracle 9i : Programming with PL/SQL: 2 - 4.6.2004 (3 days) CST Microwave Studio: 3 & 4.6.2004 (2 days) Oracle 9i : New f...

  8. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. Technical Training Monique Duval - Tel.74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Word 2003 - niveau 2 : 24 & 25.5.2004 (2 jours) VisualEliteHDL : 25 & 26.5.2004 (2 days) EXCEL 2003 - niveau 1 : 27 & 28.5.2004 (2 jours) STEP7 Programming Level 1: 1 - 4.6.2004 (4 days) Oracle 9i : Programming with PL/SQL: 2 - 4.6.2004 (3 days) CST Microwave Studio: 3 & 4.6.2004 (2 days) Oracle 9...

  9. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Instructor-led WBTechT study or follow-up for Microsoft applications : 1.4.2004 (morning) FrontPage XP - niveau 1 : 5 & 6.4.2004 (2 jours) AutoCAD 2002 - niveau 1 : 19, 20.4 et 3, 4.5.2004 (4 jours) Oracle 8i/9i - Develop Web-based Applications with PL/SQL : 19 & 20.4.2004 (2 days) Introduction to ANSYS : 20 - 23.4.2004 (4 day...

  10. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: FrontPage XP - niveau 2 : 26 & 27.4.2004 (2 jours) The Joint PVSS JCOP Framework : 26 - 30.4.2004 (5 days) Computational Electromagnetics with the ELEKTRA Module of OPERA-3D : 27 & 28.4.2004 (2 days) Hands-on Introduction to Python Programming : 3 - 5.5.2004 (3 days) LabVIEW Base 2 : 6 & 7.5.2004 (2 jours) Project Pla...

  11. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Computational Electromagnetics with the ELEKTRA Module of OPERA-3D : 27 & 28.4.2004 (2 days) Hands-on Introduction to Python Programming : 3 - 5.5.2004 (3 days) LabVIEW Base 2 : 6 & 7.5.2004 (2 jours) Project Planning with MS-Project : 6 & 13.5.2004 (2 days) Word 2003 - niveau 1 : 10 & 11.5.2004 (2 jours) Oracle 9i : SQL : 10 - 12.5.2004 (3...

  12. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: AutoCAD 2002 - niveau 1 : 19, 20.4 et 3, 4.5.2004 (4 jours) Oracle 8i/9i - Develop Web-based Applications with PL/SQL : 19 & 20.4.2004 (2 days) Introduction to ANSYS : 20 - 23.4.2004 (4 days) LabVIEW Hands-on : 20.4.2004 (half-day, p.m.) FrontPage XP - niveau 2 : 26 & 27.4.2004 (2 jours) The Joint PVSS JCOP Framework : 26 -...

  13. TECHNICAL TRAINING: Places available**

    CERN Multimedia

    2003-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch ** The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Hands-on Introduction to Python Programming : 12 - 14.11.03(3 days) ACCESS 2000 - niveau 1 : 13 & 14.11.03 (2 jours) C++ for Particle Physicists : 17 - 21.11.03 (6 X 3-hour lectures) Programmation automate Schneider TSX Premium - niveau 2 : 18 - 21.11.03 (4 jours) Project Planning with MS-Project  (free of charg...

  14. TECHNICAL TRAINING: Places available**

    CERN Multimedia

    2003-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval Tel. 74924 technical.training@cern.ch ** The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: The EDMS-MTF in practice (free of charge) : 28 -  30.10.03 (6 half-day sessions) AutoCAD 2002 – Level 1 : 3, 4, 12, 13.11.03 (4 days) LabVIEW TestStand ver. 3 : 4 & 5.11.03 (2 days) Introduction to PSpice : 4.11.03 p.m. (half-day) Hands-on Introduction to Python Programming : 12 – 14.11.03 (3 days) ACCESS ...

  15. Effective Domain Partitioning for Multi-Clock Domain IP Core Wrapper Design under Power Constraints

    Science.gov (United States)

    Yu, Thomas Edison; Yoneda, Tomokazu; Zhao, Danella; Fujiwara, Hideo

    The rapid advancement of VLSI technology has made it possible for chip designers and manufacturers to embed the components of a whole system onto a single chip, called System-on-Chip or SoC. SoCs make use of pre-designed modules, called IP-cores, which provide faster design time and quicker time-to-market. Furthermore, SoCs that operate at multiple clock domains and very low power requirements are being utilized in the latest communications, networking and signal processing devices. As a result, the testing of SoCs and multi-clock domain embedded cores under power constraints has been rapidly gaining importance. In this research, a novel method for designing power-aware test wrappers for embedded cores with multiple clock domains is presented. By effectively partitioning the various clock domains, we are able to increase the solution space of possible test schedules for the core. Since previous methods were limited to concurrently testing all the clock domains, we effectively remove this limitation by making use of bandwidth conversion, multiple shift frequencies and properly gating the clock signals to control the shift activity of various core logic elements. The combination of the above techniques gains us greater flexibility when determining an optimal test schedule under very tight power constraints. Furthermore, since it is computationally intensive to search the entire expanded solution space for the possible test schedules, we propose a heuristic 3-D bin packing algorithm to determine the optimal wrapper architecture and test schedule while minimizing the test time under power and bandwidth constraints.

  16. Is Domain Highlighting Actually Helpful in Identifying Phishing Web Pages?

    Science.gov (United States)

    Xiong, Aiping; Proctor, Robert W; Yang, Weining; Li, Ninghui

    2017-06-01

    To evaluate the effectiveness of domain highlighting in helping users identify whether Web pages are legitimate or spurious. As a component of the URL, a domain name can be overlooked. Consequently, browsers highlight the domain name to help users identify which Web site they are visiting. Nevertheless, few studies have assessed the effectiveness of domain highlighting, and the only formal study confounded highlighting with instructions to look at the address bar. We conducted two phishing detection experiments. Experiment 1 was run online: Participants judged the legitimacy of Web pages in two phases. In Phase 1, participants were to judge the legitimacy based on any information on the Web page, whereas in Phase 2, they were to focus on the address bar. Whether the domain was highlighted was also varied. Experiment 2 was conducted similarly but with participants in a laboratory setting, which allowed tracking of fixations. Participants differentiated the legitimate and fraudulent Web pages better than chance. There was some benefit of attending to the address bar, but domain highlighting did not provide effective protection against phishing attacks. Analysis of eye-gaze fixation measures was in agreement with the task performance, but heat-map results revealed that participants' visual attention was attracted by the highlighted domains. Failure to detect many fraudulent Web pages even when the domain was highlighted implies that users lacked knowledge of Web page security cues or how to use those cues. Potential applications include development of phishing prevention training incorporating domain highlighting with other methods to help users identify phishing Web pages.

  17. GCS component development cycle

    Science.gov (United States)

    Rodríguez, Jose A.; Macias, Rosa; Molgo, Jordi; Guerra, Dailos; Pi, Marti

    2012-09-01

    The GTC1 is an optical-infrared 10-meter segmented mirror telescope at the ORM observatory in Canary Islands (Spain). First light was at 13/07/2007 and since them it is in the operation phase. The GTC control system (GCS) is a distributed object & component oriented system based on RT-CORBA8 and it is responsible for the management and operation of the telescope, including its instrumentation. GCS has used the Rational Unified process (RUP9) in its development. RUP is an iterative software development process framework. After analysing (use cases) and designing (UML10) any of GCS subsystems, an initial component description of its interface is obtained and from that information a component specification is written. In order to improve the code productivity, GCS has adopted the code generation to transform this component specification into the skeleton of component classes based on a software framework, called Device Component Framework. Using the GCS development tools, based on javadoc and gcc, in only one step, the component is generated, compiled and deployed to be tested for the first time through our GUI inspector. The main advantages of this approach are the following: It reduces the learning curve of new developers and the development error rate, allows a systematic use of design patterns in the development and software reuse, speeds up the deliverables of the software product and massively increase the timescale, design consistency and design quality, and eliminates the future refactoring process required for the code.

  18. 2-component heating systems

    Energy Technology Data Exchange (ETDEWEB)

    Radtke, W

    1987-03-01

    The knowledge accumulated only recently of the damage to buildings and the hazards of formaldehyde, radon and hydrocarbons has been inducing louder calls for ventilation, which, on their part, account for the fact that increasing importance is being attached to the controlled ventilation of buildings. Two-component heating systems provide for fresh air and thermal comfort in one. While the first component uses fresh air blown directly and controllably into the rooms, the second component is similar to the Roman hypocaustic heating systems, meaning that heated outer air is circulating under the floor, thus providing for hot surfaces and thermal comfort. Details concerning the two-component heating system are presented along with systems diagrams, diagrams of the heating system and tables identifying the respective costs. Descriptions are given of the two systems components, the fast heat-up, the two-component made, the change of air, heat recovery and control systems. Comparative evaluations determine the differences between two-component heating systems and other heating systems. Conclusive remarks are dedicated to energy conservation and comparative evaluations of costs. (HWJ).

  19. Technical Writing: Past, Present and Future

    Science.gov (United States)

    Mathes, J. C. (Compiler); Pinelli, T. E. (Compiler)

    1981-01-01

    The training of technical writers and the objectives of such education are discussed. Special emphasis was placed on the communication between technical personnel and non-technical personnel. The liabilities that affect technical writers were also discussed.

  20. Paramedics' non-technical skills: a literature review.

    Science.gov (United States)

    Shields, Allan; Flin, Rhona

    2013-05-01

    Healthcare organisations have started to examine the impact that the human worker has on patient safety. Adopting the Crew Resource Management (CRM) approach, used in aviation, the CRM or non-technical skills of anaesthetists, surgeons, scrub practitioners and emergency physicians have recently been identified to assist in their training and assessment. Paramedics are exposed to dynamic and dangerous situations where patients have to be managed, often with life-threatening injuries or illness. As in other safety-critical domains, the technical skills of paramedics are complemented by effective non-technical skills. The aim of this paper was to review the literature on the non-technical (social and cognitive) skills used by paramedics. This review was undertaken as part of a task analysis to identify the non-technical skills used by paramedics. Of the seven papers reviewed, the results have shown very little research on this topic and so reveal a gap in the understanding of paramedic non-technical skills.

  1. Applying Standard Industrial Components for Active Magnetic Bearings

    Directory of Open Access Journals (Sweden)

    Bert-Uwe Koehler

    2017-02-01

    Full Text Available With the increasing number of active magnetic bearing applications, satisfying additional requirements is becoming increasingly more important. As for every technology, moving away from being a niche product and achieving a higher level of maturity, these requirements relate to robustness, reliability, availability, safety, security, traceability, certification, handling, flexibility, reporting, costs, and delivery times. Employing standard industrial components, such as those from flexible modular motion control drive systems, is an approach that allows these requirements to be satisfied while achieving rapid technological innovation. In this article, we discuss technical and non-technical aspects of using standard industrial components in magnetic bearing applications.

  2. METHOD IMPROVEMENT FOR DETERMINING THE TECHNICAL LEVEL OF CIVIL AIRCRAFT

    Directory of Open Access Journals (Sweden)

    2016-01-01

    Full Text Available Aircraft are high-tech engineering products which are characterized by a wide range of properties including the two most important groups that respectively characterize the efficiency and technical level.Improving the aircraft efficiency is an essential factor for air transport development, but the efficiency can not be fully describe the technical system, especially in forecasting and new technology requirements development. Aircraft de- signer must evaluate the prospects of a technical solution, but it’s not always possible to calculate the efficiency accuratelyat the design stage. The operator should be able to choose the most technically-advanced aircraft available in the market inorder not to let it grow obsolete quickly. This determines the need for non-economic evaluation of technical systems that can be done by assessment of their technical level.The technical level is a general index that includes a set of technical perfection indicators. Technical perfection is reflected in terms of material and energy intensity, in terms of ergonomics, safety, etc. and is achieved as a result of origi- nal design solutions, the use of new high-strength low-density materials, the introduction of advanced technological pro-cesses, calculation methods, verification, testing, etc.There is a tight connection between the product properties and its weight, because weight is the material reflection of these properties. Therefore, improvement of the product properties usually leads to an intense increase of its weight. To deal with this phenomenon is only possible with widely using scientific and technical progress results. In accordance with this, the technical perfection can be interpreted as a major component of quality that is created without the weight increase. This approach requires investment in research and testing new technical solutions.The method was developed to determine the technical level of civil long-haul aircraft which has been modified to

  3. An Algebro-Topological Description of Protein Domain Structure

    Science.gov (United States)

    Penner, Robert Clark; Knudsen, Michael; Wiuf, Carsten; Andersen, Jørgen Ellegaard

    2011-01-01

    The space of possible protein structures appears vast and continuous, and the relationship between primary, secondary and tertiary structure levels is complex. Protein structure comparison and classification is therefore a difficult but important task since structure is a determinant for molecular interaction and function. We introduce a novel mathematical abstraction based on geometric topology to describe protein domain structure. Using the locations of the backbone atoms and the hydrogen bonds, we build a combinatorial object – a so-called fatgraph. The description is discrete yet gives rise to a 2-dimensional mathematical surface. Thus, each protein domain corresponds to a particular mathematical surface with characteristic topological invariants, such as the genus (number of holes) and the number of boundary components. Both invariants are global fatgraph features reflecting the interconnectivity of the domain by hydrogen bonds. We introduce the notion of robust variables, that is variables that are robust towards minor changes in the structure/fatgraph, and show that the genus and the number of boundary components are robust. Further, we invesigate the distribution of different fatgraph variables and show how only four variables are capable of distinguishing different folds. We use local (secondary) and global (tertiary) fatgraph features to describe domain structures and illustrate that they are useful for classification of domains in CATH. In addition, we combine our method with two other methods thereby using primary, secondary, and tertiary structure information, and show that we can identify a large percentage of new and unclassified structures in CATH. PMID:21629687

  4. Domain Decomposition Solvers for Frequency-Domain Finite Element Equations

    KAUST Repository

    Copeland, Dylan; Kolmbauer, Michael; Langer, Ulrich

    2010-01-01

    The paper is devoted to fast iterative solvers for frequency-domain finite element equations approximating linear and nonlinear parabolic initial boundary value problems with time-harmonic excitations. Switching from the time domain to the frequency domain allows us to replace the expensive time-integration procedure by the solution of a simple linear elliptic system for the amplitudes belonging to the sine- and to the cosine-excitation or a large nonlinear elliptic system for the Fourier coefficients in the linear and nonlinear case, respectively. The fast solution of the corresponding linear and nonlinear system of finite element equations is crucial for the competitiveness of this method. © 2011 Springer-Verlag Berlin Heidelberg.

  5. Domain Decomposition Solvers for Frequency-Domain Finite Element Equations

    KAUST Repository

    Copeland, Dylan

    2010-10-05

    The paper is devoted to fast iterative solvers for frequency-domain finite element equations approximating linear and nonlinear parabolic initial boundary value problems with time-harmonic excitations. Switching from the time domain to the frequency domain allows us to replace the expensive time-integration procedure by the solution of a simple linear elliptic system for the amplitudes belonging to the sine- and to the cosine-excitation or a large nonlinear elliptic system for the Fourier coefficients in the linear and nonlinear case, respectively. The fast solution of the corresponding linear and nonlinear system of finite element equations is crucial for the competitiveness of this method. © 2011 Springer-Verlag Berlin Heidelberg.

  6. The Unknown Component Problem Theory and Applications

    CERN Document Server

    Villa, Tiziano; Brayton, Robert K; Mishchenko, Alan; Petrenko, Alexandre; Sangiovanni-Vincentelli, Alberto

    2012-01-01

    The Problem of the Unknown Component: Theory and Applications addresses the issue of designing a component that, combined with a known part of a system, conforms to an overall specification. The authors tackle this problem by solving abstract equations over a language. The most general solutions are studied when both synchronous and parallel composition operators are used. The abstract equations are specialized to languages associated with important classes of automata used for modeling systems. The book is a blend of theory and practice, which includes a description of a software package with applications to sequential synthesis of finite state machines. Specific topologies interconnecting the components, exact and heuristic techniques, and optimization scenarios are studied. Finally the scope is enlarged to domains like testing, supervisory control, game theory and synthesis for special omega languages. The authors present original results of the authors along with an overview of existing ones.

  7. Technical considerations in materials management policy development

    International Nuclear Information System (INIS)

    Avci, H.; Goldberg, M.

    1996-01-01

    Under the Materials-in-Inventory (MIN) initiative, US DOE intends to develop policies to ensure that materials are managed and use efficiently, cost-effectively, and safely throughout DOE. The MIN initiative covers depleted uranium, scrap metals, chemicals, explosives, spent nuclear fuel, lead, alkali metals, etc.; by far the largest component is depleted uranium hexafluoride (DUF6). A technically defensible approach has been developed and is being used to select a long-term management strategy for DOE's DUF6 inventory. The same approach can be adapted to management of other materials in inventory that have the potential to be reutilized

  8. The Fermilab Main Injector Technical Design Handbook

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1994-08-01

    This report contains a description of the design, cost estimate, and construction schedule of the Fermilab Main Injector (FMI) Project. The technical, cost, and schedule baselines for the FMI Project have already been established and may be found in the Fermilab Main Injector Title I Design Report, issued in August 1992. This report updates and expands upon the design and schedule for construction of all subsystem components and associated civil construction described in the Title I Design Report. The facilities described have been designed in conformance with DOE 6430.1A, "United States Department of Energy General Design Criteria."

  9. Tiered Auctions for Multi-Agent Coordination in Domains with Precedence Constraints

    National Research Council Canada - National Science Library

    Jones, E. G; Dias, M. B; Stentz, Anthony

    2008-01-01

    .... Among these domains are some that require robots to interact closely at particular times and locations to accomplish some task components, but otherwise allow the team members to act independently...

  10. On the initial condition problem of the time domain PMCHWT surface integral equation

    KAUST Repository

    Uysal, Ismail Enes; Bagci, Hakan; Ergin, A. Arif; Ulku, H. Arda

    2017-01-01

    Non-physical, linearly increasing and constant current components are induced in marching on-in-time solution of time domain surface integral equations when initial conditions on time derivatives of (unknown) equivalent currents are not enforced

  11. Technical Support Essentials Advice to Succeed in Technical Support

    CERN Document Server

    Sanchez, Andrew

    2010-01-01

    Technical Support Essentials is a book about the many facets of technical support. It attempts to provide a wide array of topics to serve as points of improvement, discussion, or simply topics that you might want to learn. The topics range from good work habits to the way technical supportgroups establish their own style of work. This book applies theories, models, and concepts synthesized from existing research in other fields-such as management, economics, leadership, and psychology-and connects them to technical support. The goal is to build on the work of others and allow their success to

  12. Technical standards in the law of technical safety

    International Nuclear Information System (INIS)

    Marburger, P.

    1985-01-01

    Technical standards are of great importance for the closer definition of inexact terms of law, for instance ''generally accepted technical rules'', ''state of the art'', ''state of science and technology'' or similar normative terms, in the law of technical safety. The paper discusses with whom the authority for regulating this sector of law rests, deals with the different ways of how technical standards are used by the law (''anticipated expert opinion'', reference to such standards in law and administration) and points out demands on the procedure of standardization. (orig.) [de

  13. Learning Local Components to Understand Large Bayesian Networks

    DEFF Research Database (Denmark)

    Zeng, Yifeng; Xiang, Yanping; Cordero, Jorge

    2009-01-01

    (domain experts) to extract accurate information from a large Bayesian network due to dimensional difficulty. We define a formulation of local components and propose a clustering algorithm to learn such local components given complete data. The algorithm groups together most inter-relevant attributes......Bayesian networks are known for providing an intuitive and compact representation of probabilistic information and allowing the creation of models over a large and complex domain. Bayesian learning and reasoning are nontrivial for a large Bayesian network. In parallel, it is a tough job for users...... in a domain. We evaluate its performance on three benchmark Bayesian networks and provide results in support. We further show that the learned components may represent local knowledge more precisely in comparison to the full Bayesian networks when working with a small amount of data....

  14. A Fast, Efficient Domain Adaptation Technique for Cross-Domain Electroencephalography(EEG-Based Emotion Recognition

    Directory of Open Access Journals (Sweden)

    Xin Chai

    2017-05-01

    Full Text Available Electroencephalography (EEG-based emotion recognition is an important element in psychiatric health diagnosis for patients. However, the underlying EEG sensor signals are always non-stationary if they are sampled from different experimental sessions or subjects. This results in the deterioration of the classification performance. Domain adaptation methods offer an effective way to reduce the discrepancy of marginal distribution. However, for EEG sensor signals, both marginal and conditional distributions may be mismatched. In addition, the existing domain adaptation strategies always require a high level of additional computation. To address this problem, a novel strategy named adaptive subspace feature matching (ASFM is proposed in this paper in order to integrate both the marginal and conditional distributions within a unified framework (without any labeled samples from target subjects. Specifically, we develop a linear transformation function which matches the marginal distributions of the source and target subspaces without a regularization term. This significantly decreases the time complexity of our domain adaptation procedure. As a result, both marginal and conditional distribution discrepancies between the source domain and unlabeled target domain can be reduced, and logistic regression (LR can be applied to the new source domain in order to train a classifier for use in the target domain, since the aligned source domain follows a distribution which is similar to that of the target domain. We compare our ASFM method with six typical approaches using a public EEG dataset with three affective states: positive, neutral, and negative. Both offline and online evaluations were performed. The subject-to-subject offline experimental results demonstrate that our component achieves a mean accuracy and standard deviation of 80.46% and 6.84%, respectively, as compared with a state-of-the-art method, the subspace alignment auto-encoder (SAAE, which

  15. Replaceable LMFBR core components

    International Nuclear Information System (INIS)

    Evans, E.A.; Cunningham, G.W.

    1976-01-01

    Much progress has been made in understanding material and component performance in the high temperature, fast neutron environment of the LMFBR. Current data have provided strong assurance that the initial core component lifetime objectives of FFTF and CRBR can be met. At the same time, this knowledge translates directly into the need for improved core designs that utilize improved materials and advanced fuels required to meet objectives of low doubling times and extended core component lifetimes. An industrial base for the manufacture of quality core components has been developed in the US, and all procurements for the first two core equivalents for FFTF will be completed this year. However, the problem of fabricating recycled plutonium while dramatically reducing fabrication costs, minimizing personnel exposure, and protecting public health and safety must be addressed

  16. Explosive Components Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The 98,000 square foot Explosive Components Facility (ECF) is a state-of-the-art facility that provides a full-range of chemical, material, and performance analysis...

  17. Development of an evaluation method for the quality of NPP MCR operators' communication using Work Domain Analysis (WDA)

    International Nuclear Information System (INIS)

    Jang, Inseok; Park, Jinkyun; Seong, Poonghyun

    2011-01-01

    Research highlights: → No evaluation method is available for operators' communication quality in NPPs. → To model this evaluation method, the Work Domain Analysis (WDA) method was found. → This proposed method was applied to NPP MCR operators. → The quality of operators' communication can be evaluated with the propose method. - Abstract: The evolution of work demands has seen industrial evolution itself evolve into the computerization of these demands, making systems more complex. This field is now known as the Complex Socio-Technical System. As communication failures are problems associated with Complex Socio-Technical Systems, it has been discovered that communication failures are the cause of many incidents and accidents in various industries, including the nuclear, aerospace and railway industries. Despite the fact that there have been many studies on the severity of communication failures, there is no evaluation method for operators' communication quality in Nuclear Power Plants (NPPs). Therefore, the objectives of this study are to develop an evaluation method for the quality of NPP Main Control Room (MCR) operators' communication and to apply the proposed method to operators in a full-scope simulator. To develop the proposed method, the Work Domain Analysis (WDA) method is introduced. Several characteristics of WDA, including Abstraction Decomposition Space (ADS) and the diagonal of ADS are the important points in developing an evaluation method for the quality of NPP MCR operators' communication. In addition, to apply the proposed method, nine teams working in NPPs participated in a field simulation. The results of this evaluation reveal that operators' communication quality improved as a greater proportion of the components in the developed evaluation criteria were mentioned. Therefore, the proposed method could be useful for evaluating the communication quality in any complex system.

  18. Using the Domain Identification Model to Study Major and Career Decision-Making Processes

    Science.gov (United States)

    Tendhar, Chosang; Singh, Kusum; Jones, Brett D.

    2018-01-01

    The purpose of this study was to examine the extent to which (1) a domain identification model could be used to predict students' engineering major and career intentions and (2) the MUSIC Model of Motivation components could be used to predict domain identification. The data for this study were collected from first-year engineering students. We…

  19. On the precision of an estimator of Mean for Domains in Double ...

    African Journals Online (AJOL)

    The results show that there is a positive contribution to the variance of the estimator which varies from one stratum to another. This addition vanishes where the domain coincides with a stratum. The total sampling variance depends only on components of variance for the domain and is inversely related to the total sample ...

  20. Structural and functional aspects of winged-helix domains at the core of transcription initiation complexes.

    Science.gov (United States)

    Teichmann, Martin; Dumay-Odelot, Hélène; Fribourg, Sébastien

    2012-01-01

    The winged helix (WH) domain is found in core components of transcription systems in eukaryotes and prokaryotes. It represents a sub-class of the helix-turn-helix motif. The WH domain participates in establishing protein-DNA and protein-protein-interactions. Here, we discuss possible explanations for the enrichment of this motif in transcription systems.

  1. Asymmetric cross-domain interference between two working memory tasks : Implications for models of working memory

    NARCIS (Netherlands)

    Morey, Candice C.; Morey, Richard D.; van der Reijden, Madeleine; Holweg, Margot

    2013-01-01

    Observations of higher dual-task costs for within-domain than cross-domain task combinations constitute classic evidence for multi-component models of working memory (e.g., Baddeley, 1986; Logie, 2011). However, we report an asymmetric pattern of interference between verbal and visual-spatial tasks,

  2. Design of an online charging system to support IMS-based inter-domain composite services

    NARCIS (Netherlands)

    Le, V.M.; Huitema, G.B.; Rumph, F.J.; Nieuwenhuis, Lambertus Johannes Maria; van Beijnum, Bernhard J.F.; Pfeifer, T.; Bellavista, P.

    2009-01-01

    For service providers online charging of composite services is necessary in order to manage financial risks of service delivery in multi-domain environments. At service level, inter-domain composite services consist of one or more service components, e.g. access service, IMS communication service or

  3. Component fragility research program

    International Nuclear Information System (INIS)

    Tsai, N.C.; Mochizuki, G.L.; Holman, G.S.

    1989-11-01

    To demonstrate how ''high-level'' qualification test data can be used to estimate the ultimate seismic capacity of nuclear power plant equipment, we assessed in detail various electrical components tested by the Pacific Gas ampersand Electric Company for its Diablo Canyon plant. As part of our Phase I Component Fragility Research Program, we evaluated seismic fragility for five Diablo Canyon components: medium-voltage (4kV) switchgear; safeguard relay board; emergency light battery pack; potential transformer; and station battery and racks. This report discusses our Phase II fragility evaluation of a single Westinghouse Type W motor control center column, a fan cooler motor controller, and three local starters at the Diablo Canyon nuclear power plant. These components were seismically qualified by means of biaxial random motion tests on a shaker table, and the test response spectra formed the basis for the estimate of the seismic capacity of the components. The seismic capacity of each component is referenced to the zero period acceleration (ZPA) and, in our Phase II study only, to the average spectral acceleration (ASA) of the motion at its base. For the motor control center, the seismic capacity was compared to the capacity of a Westinghouse Five-Star MCC subjected to actual fragility tests by LLNL during the Phase I Component Fragility Research Program, and to generic capacities developed by the Brookhaven National Laboratory for motor control center. Except for the medium-voltage switchgear, all of the components considered in both our Phase I and Phase II evaluations were qualified in their standard commercial configurations or with only relatively minor modifications such as top bracing of cabinets. 8 refs., 67 figs., 7 tabs

  4. Refractory alloy component fabrication

    International Nuclear Information System (INIS)

    Young, W.R.

    1984-01-01

    Purpose of this report is to describe joining procedures, primarily welding techniques, which were developed to construct reliable refractory alloy components and systems for advanced space power systems. Two systems, the Nb-1Zr Brayton Cycle Heat Receiver and the T-111 Alloy Potassium Boiler Development Program, are used to illustrate typical systems and components. Particular emphasis is given to specific problems which were eliminated during the development efforts. Finally, some thoughts on application of more recent joining technology are presented. 78 figures

  5. Impact test of components

    International Nuclear Information System (INIS)

    Borsoi, L.; Buland, P.; Labbe, P.

    1987-01-01

    Stops with gaps are currently used to support components and piping: it is simple, low cost, efficient and permits free thermal expansion. In order to keep the nonlinear nature of stops, such design is often modeled by beam elements (for the component) and nonlinear springs (for the stops). This paper deals with the validity and the limits of these models through the comparison of computational and experimental results. The experimental results come from impact laboratory tests on a simplified mockup. (orig.)

  6. Tore Supra: technical description

    International Nuclear Information System (INIS)

    1985-08-01

    This report is aimed, after a brief recall of physics and technologic perspectives of Tore Supra, at giving a detailed description of the basic machine; details of each component are defined. Volume 1 is specifically concerned with the general aspects of Tore Supra and the toroidal field system [fr

  7. On technical security issues in cloud computing

    DEFF Research Database (Denmark)

    Jensen, Meiko; Schwenk, Jörg; Gruschka, Nils

    2009-01-01

    , however, there are still some challenges to be solved. Amongst these are security and trust issues, since the user's data has to be released to the Cloud and thus leaves the protection sphere of the data owner. Most of the discussions on this topics are mainly driven by arguments related to organisational......The Cloud Computing concept offers dynamically scalable resources provisioned as a service over the Internet. Economic benefits are the main driver for the Cloud, since it promises the reduction of capital expenditure (CapEx) and operational expenditure (OpEx). In order for this to become reality...... means. This paper focusses on technical security issues arising from the usage of Cloud services and especially by the underlying technologies used to build these cross-domain Internet-connected collaborations....

  8. Technical specification use and application

    International Nuclear Information System (INIS)

    Williamson, D.; Hoffman, D.R.

    1991-01-01

    Since early 1988 intensive efforts have been under way to produce a new and improved Standard Technical Specification. The program involves a coordinated effort between utility personnel representing each of the four nuclear steam supply system (NSSS) product lines, the NSSS vendors, and the US Nuclear Regulatory Commission (NRC). This intensive work period is actually the culmination of a decade of rhetoric about shortcomings of the existing technical specifications. Work on the improved technical specifications provided a unique forum for intense philosophical discussions between the users and enforcers of technical specifications, the outcome of which could have an impact on all licensees. Some of the more intriguing difficulties in the use and application of existing technical specifications, as well as discussions of the resolutions being applied in the improved technical specifications and the dilemmas remaining to be resolved are discussed in the paper

  9. Technical applications of aerogels

    International Nuclear Information System (INIS)

    Hrubesh, L.W.

    1997-01-01

    Aerogel materials posses such a wide variety of exceptional properties that a striking number of applications have developed for them. Many of the commercial applications of aerogels such as catalysts, thermal insulation, windows, and particle detectors are still under development and new application as have been publicized since the ISA4 Conference in 1994: e.g.; supercapacitors, insulation for heat storage in automobiles, electrodes for capacitive deionization, etc. More applications are evolving as the scientific and engineering community becomes familiar with the unusual and exceptional physical properties of aerogels, there are also scientific and technical application, as well. This paper discusses a variety of applications under development at Lawrence Livermore National Laboratory for which several types of aerogels are formed in custom sizes and shapes. Particular discussions will focus on the uses of aerogels for physics experiments which rely on the exceptional, sometimes unique, properties of aerogels

  10. Technical Report - FINAL

    Energy Technology Data Exchange (ETDEWEB)

    Barbara Luke, Director, UNLV Engineering Geophysics Laboratory

    2007-04-25

    Improve understanding of the earthquake hazard in the Las Vegas Valley and to assess the state of preparedness of the area's population and structures for the next big earthquake. 1. Enhance the seismic monitoring network in the Las Vegas Valley 2. Improve understanding of deep basin structure through active-source seismic refraction and reflection testing 3. Improve understanding of dynamic response of shallow sediments through seismic testing and correlations with lithology 4. Develop credible earthquake scenarios by laboratory and field studies, literature review and analyses 5. Refine ground motion expectations around the Las Vegas Valley through simulations 6. Assess current building standards in light of improved understanding of hazards 7. Perform risk assessment for structures and infrastructures, with emphasis on lifelines and critical structures 8. Encourage and facilitate broad and open technical interchange regarding earthquake safety in southern Nevada and efforts to inform citizens of earthquake hazards and mitigation opportunities

  11. Socio-Technical Structure

    DEFF Research Database (Denmark)

    Rose, Jeremy; Lindgren, Rikard; Henfridsson, Ole

    2004-01-01

    a reference discipline in its own right (in other words a theory exporter), this paper offers an example of integrative theory development. Instead of adapting a theory from another discipline or building a theory from empirical data, we examine the structure concept in some of its various theoretical......When it comes to investigating the relationship between the social and the technical, IS has been a net importer of theories. These theories often carry differing interpretations of central concepts, which then become both confusing and difficult to integrate. In response to calls for IS to become...... adaptations in IS and try to integrate them to produce theory that focuses on IS concerns whilst resolving some of the major areas of contention. Both social and technological versions of structure are investigated through three theoretical IS perspectives drawn from different reference disciplines. The first...

  12. LLNL 1981: technical horizons

    International Nuclear Information System (INIS)

    1981-07-01

    Research programs at LLNL for 1981 are described in broad terms. In his annual State of the Laboratory address, Director Roger Batzel projected a $481 million operating budget for fiscal year 1982, up nearly 13% from last year. In projects for the Department of Energy and the Department of Defense, the Laboratory applies its technical facilities and capabilities to nuclear weapons design and development and other areas of defense research that include inertial confinement fusion, nonnuclear ordnances, and particle-beam technology. LLNL is also applying its unique experience and capabilities to a variety of projects that will help the nation meet its energy needs in an environmentally acceptable manner. A sampling of recent achievements by LLNL support organizations indicates their diversity

  13. Technical Training Seminar

    CERN Multimedia

    2003-01-01

    Wednesday 19 November From 9:30 to 17:30 - IT Amphitheatre bldg.31 3-004 2003 Data Transmission Design Seminar - TEXAS INSTRUMENTS The one-day 2003 Data Transmission Design Seminar is part of a series of technical seminars produced by Texas Instruments. This series of seminars will introduce system solutions based on different standards according to their respective requirements. It will include topics containing a blend of basic principles and hands-on application examples, along with layout-guidelines. • Basics and Practical Examples of Data-Transmission • Low Voltage Differential Signaling (LVDS) • Connectivity and PC-based Links • Industrial Interfaces • Parallel Bus Systems and Clock-Distribution-Circuits (CDC) This Seminar will be of interest to hardware designers and system engineers dealing with the realization of system- or board-level interfaces based on various transmission standards. Language: English Free seminar, no registration Organiser: John ...

  14. Technical Math For Dummies

    CERN Document Server

    Schoenborn, Barry

    2010-01-01

    Technical Math For Dummies is your one-stop, hands-on guide to acing the math courses you’ll encounter as you work toward getting your degree, certifacation, or�license in the skilled trades. You’ll get easy-to-follow, plain-English guidance on mathematical formulas and methods that professionals use every day in the automotive, health, construction, licensed trades, maintenance, and other trades. You’ll learn how to apply concepts of algebra, geometry, and trigonometry and their formulas related to occupational areas of study. Plus, you’ll find out how to perform basic arithmetic

  15. Technical Training: ELEC-2005

    CERN Multimedia

    Davide Vitè

    2005-01-01

    ELEC-2005 - Electronics in High Energy Physics: Autumn Term (November-December 2005) ELEC-2005 is a new course series on modern electronics, given by CERN physicists and engineers within the framework of the 2005 Technical Training Programme, in an extended format of the ELEC-2002 course series. This new, comprehensive course series is designed for people who are not electronics specialists, for example physicists, engineers and technicians working at or visiting the laboratory, who use or will use electronics in their present or future activities, in particular in the context of the LHC accelerator and experiments. ELEC-2005 is composed of four Terms. The Winter (Introduction to electronics in HEP), Spring (Integrated circuits and VLSI technology for physics), and Summer (System electronics for physics: Issues) Terms already took place. The Autumn Term: Electronics applications in HEP experiments (November-December, 10 lectures) is now open for online registration, and will start on November 8th with the...

  16. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Eggeman, Tim [ZeaChem Inc., Lakewood, CO (United States); O' Neill, Brian [ZeaChem Inc., Lakewood, CO (United States)

    2016-08-17

    ZeaChem Inc. and US DOE successfully demonstrated the ZeaChem process for producing sugars and ethanol from high-impact biomass feedstocks. The project was executed over a 5-year period under a $31.25 million cooperative agreement (80:20 Federal:ZeaChem cost share). The project was managed by dividing it into three budget periods. Activities during Budget Period 1 were limited to planning, permitting, and other pre-construction planning. Budget Period 2 activities included engineering, procurement, construction, commissioning, start-up and initial operations through the Independent Engineer Test Runs. The scope of construction was limited to the Chem Frac and Hydrogenolysis units, as the Core Facility was already in place. Construction was complete in December 2012, and the first cellulosic ethanol was produced in February 2013. Additional operational test runs were conducted during Budget Period 3 (completed June 2015) using hybrid poplar, corn stover, and wheat straw feedstocks, resulting in the production of cellulosic ethanol and various other biorefinery intermediates. The research adds to the understanding of the Chem Frac and Hydrogenolysis technologies in that the technical performance of each unit was measured, and the resulting data and operational experience can be used as the basis for engineering designs, thus mitigating risks for deployment in future commercial facilities. The Chem Frac unit was initially designed to be operated as two-stage dilute acid hydrolysis, with first stage conditions selected to remove the hemicellulose fraction of the feedstock, and the second stage conditions selected to remove the cellulose fraction. While the Chem Frac unit met or exceeded the design capacity of 10 ton(dry)/day, the technical effectiveness of the Chem Frac unit was below expectations in its initial two-stage dilute acid configuration. The sugars yields were low, the sugars were dilute, and the sugars had poor fermentability caused by excessive inhibitors

  17. Final technical report

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    gas jet chamber and laser beam path from the final focusing mirror. The project consists of three phases: Phase 1: Fundamental studies of cutting front mechanisms, beam propagation, nozzle design and chemical reactions in the cut kerf with special emphasize on high laser powers and thick sections...... cutting nozzle which can be adjusted independently to the laser beam has been developed. The position of the focus relative the workpiece can be adjusted to cutting applications with relatively large processing windows, i.e. both mild and stainless steels, and of a broad thickness range. A build-in auto......This project entails research with the goal to extend laser cutting of steel based metals to thickness above 20 mm and laser powers in the 10 kW range, with adequate accuracy and economically viable cutting speeds. The technical approach is to develop mirror based cutting heads with truly coaxial...

  18. TECHNICAL TRAINING PROGRAMME

    CERN Multimedia

    Davide Vitè

    2002-01-01

    CLEAN-2002: Working in a Cleanroom A new, free of charge, half-day seminar is offered in the context of Technical Training for the LHC, for personnel working or managing activities in a cleanroom (for example physicists, engineers and technicians working at or visiting the laboratory). CLEAN-2002 is aimed at raising awareness about good working practices in a cleanroom, and at providing practical examples, analysis tools, and documentation. Specific problems put forward beforehand by attendees will also be addressed, if possible. More information and registration is available HERE The next session, in English, will be on 24.4 (afternoon). Other sessions, in French and English, will be offered following demand. Organiser: Davide Vitè / HR-TD / 75141 Davide.Vite@cern.ch

  19. Technical Due Diligence

    DEFF Research Database (Denmark)

    Jensen, Per Anker; Varano, Mattia

    2011-01-01

    carried out for buyers or sellers involved in real estate transactions. It can also be part of mergers including real estate and other assets or part of facilities management outsourcing. This paper is based on a case study and an interview survey of companies involved in TDD consulting in Denmark......Technical Due Diligence (TDD) as an evaluation of the performance of constructed facilities has become an important new field of practice for consultants. Before the financial crisis started in autumn 2008 it represented the fastest growing activity in some consulting companies. TDD is mostly...... and Italy during 2009. The research identifies the current practice and compares it with the recommended practice in international guidelines. The current practice is very diverse and could in many cases be improved by a more structured approach and stricter adherence to international guidelines. However...

  20. ITER technical basis

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-01-01

    Following on from the Final Report of the EDA(DS/21), and the summary of the ITER Final Design report(DS/22), the technical basis gives further details of the design of ITER. It is in two parts. The first, the Plant Design specification, summarises the main constraints on the plant design and operation from the viewpoint of engineering and physics assumptions, compliance with safety regulations, and siting requirements and assumptions. The second, the Plant Description Document, describes the physics performance and engineering characteristics of the plant design, illustrates the potential operational consequences foe the locality of a generic site, gives the construction, commissioning, exploitation and decommissioning schedule, and reports the estimated lifetime costing based on data from the industry of the EDA parties.