WorldWideScience

Sample records for components domains technical

  1. Domain adaptation via transfer component analysis.

    Science.gov (United States)

    Pan, Sinno Jialin; Tsang, Ivor W; Kwok, James T; Yang, Qiang

    2011-02-01

    Domain adaptation allows knowledge from a source domain to be transferred to a different but related target domain. Intuitively, discovering a good feature representation across domains is crucial. In this paper, we first propose to find such a representation through a new learning method, transfer component analysis (TCA), for domain adaptation. TCA tries to learn some transfer components across domains in a reproducing kernel Hilbert space using maximum mean miscrepancy. In the subspace spanned by these transfer components, data properties are preserved and data distributions in different domains are close to each other. As a result, with the new representations in this subspace, we can apply standard machine learning methods to train classifiers or regression models in the source domain for use in the target domain. Furthermore, in order to uncover the knowledge hidden in the relations between the data labels from the source and target domains, we extend TCA in a semisupervised learning setting, which encodes label information into transfer components learning. We call this extension semisupervised TCA. The main contribution of our work is that we propose a novel dimensionality reduction framework for reducing the distance between domains in a latent space for domain adaptation. We propose both unsupervised and semisupervised feature extraction approaches, which can dramatically reduce the distance between domain distributions by projecting data onto the learned transfer components. Finally, our approach can handle large datasets and naturally lead to out-of-sample generalization. The effectiveness and efficiency of our approach are verified by experiments on five toy datasets and two real-world applications: cross-domain indoor WiFi localization and cross-domain text classification.

  2. Technical considerations relative to removal of sodium from LMFBR components

    International Nuclear Information System (INIS)

    McDonald, J.S.; Asquith, J.G.

    1975-01-01

    Reviewed in this paper are technical considerations which are of importance in choosing between an alcohol process and a moist nitrogen process for the removal of sodium from LMFBR components. Results observed in laboratory tests and in the cleaning of large scale components (e.g. a 28 MWt Modular Steam Generator Test Unit) are presented and discussed. (author)

  3. Formation of Cell Membrane Component Domains in Artificial Lipid Bilayer.

    Science.gov (United States)

    Tero, Ryugo; Fukumoto, Kohei; Motegi, Toshinori; Yoshida, Miyu; Niwano, Michio; Hirano-Iwata, Ayumi

    2017-12-20

    The lipid bilayer environment around membrane proteins strongly affects their structure and functions. Here, we aimed to study the fusion of proteoliposomes (PLs) derived from cultured cells with an artificial lipid bilayer membrane and the distribution of the PL components after the fusion. PLs, which were extracted as a crude membrane fraction from Chinese hamster ovary (CHO) cells, formed isolated domains in a supported lipid bilayer (SLB), comprising phosphatidylcholine (PC), phosphatidylethanolamine (PE), and cholesterol (Chol), after the fusion. Observation with a fluorescence microscope and an atomic force microscope showed that the membrane fusion occurred selectively at microdomains in the PC + PE + Chol-SLB, and that almost all the components of the PL were retained in the domain. PLs derived from human embryonic kidney 293 (HEK) cells also formed isolated domains in the PC + PE + Chol-SLB, but their fusion kinetics was different from that of the CHO-PLs. We attempted to explain the mechanism of the PL-SLB fusion and the difference between CHO- and HEK-PLs, based on a kinetic model. The domains that contained the whole cell membrane components provided environments similar to that of natural cell membranes, and were thus effective for studying membrane proteins using artificial lipid bilayer membranes.

  4. Cross Domain Deterrence: Livermore Technical Report, 2014-2016

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Peter D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bahney, Ben [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Matarazzo, Celeste [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Markey, Michael [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pearl, Jonathan [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-08-03

    Lawrence Livermore National Laboratory (LLNL) is an original collaborator on the project titled “Deterring Complex Threats: The Effects of Asymmetry, Interdependence, and Multi-polarity on International Strategy,” (CDD Project) led by the UC Institute on Global Conflict and Cooperation at UCSD under PIs Jon Lindsay and Erik Gartzke , and funded through the DoD Minerva Research Initiative. In addition to participating in workshops and facilitating interaction among UC social scientists, LLNL is leading the computational modeling effort and assisting with empirical case studies to probe the viability of analytic, modeling and data analysis concepts. This report summarizes LLNL work on the CDD Project to date, primarily in Project Years 1-2, corresponding to Federal fiscal year 2015. LLNL brings two unique domains of expertise to bear on this Project: (1) access to scientific expertise on the technical dimensions of emerging threat technology, and (2) high performance computing (HPC) expertise, required for analyzing the complexity of bargaining interactions in the envisioned threat models. In addition, we have a small group of researchers trained as social scientists who are intimately familiar with the International Relations research. We find that pairing simulation scientists, who are typically trained in computer science, with domain experts, social scientists in this case, is the most effective route to developing powerful new simulation tools capable of representing domain concepts accurately and answering challenging questions in the field.

  5. Modular Domain-Specific Language Components in Scala

    DEFF Research Database (Denmark)

    Hofer, Christian; Ostermann, Klaus

    2010-01-01

    Programs in domain-­specific embedded languages (DSELs) can be represented in the host language in different ways, for instance implicitly as libraries, or explicitly in the form of abstract syntax trees. Each of these representations has its own strengths and weaknesses. The implicit approach ha...... or transformation. We propose a new design for implementing DSELs in Scala which makes it easy to use different program representations at the same time. It enables the DSL implementor to define modular language components and to compose transformations and interpretations for them....

  6. Checking Architectural and Implementation Constraints for Domain-Specific Component Frameworks using Models

    OpenAIRE

    Noguera, Carlos; Loiret, Frédéric

    2009-01-01

    Acceptance rate: 38%; International audience; Software components are used in various application domains, and many component models and frameworks have been proposed to fulfill domain-specific requirements. The ad-hoc development of these component frameworks hampers the reuse of tools and abstractions across different frameworks. We believe that in order to promote the reuse of components within various domain contexts an homogeneous design approach is needed. A key requirement of such an a...

  7. Hybrid time/frequency domain modeling of nonlinear components

    DEFF Research Database (Denmark)

    Wiechowski, Wojciech Tomasz; Lykkegaard, Jan; Bak, Claus Leth

    2007-01-01

    This paper presents a novel, three-phase hybrid time/frequency methodology for modelling of nonlinear components. The algorithm has been implemented in the DIgSILENT PowerFactory software using the DIgSILENT Programming Language (DPL), as a part of the work described in [1]. Modified HVDC benchmark...

  8. Cognitive components of regularity processing in the auditory domain.

    Directory of Open Access Journals (Sweden)

    Stefan Koelsch

    Full Text Available BACKGROUND: Music-syntactic irregularities often co-occur with the processing of physical irregularities. In this study we constructed chord-sequences such that perceived differences in the cognitive processing between regular and irregular chords could not be due to the sensory processing of acoustic factors like pitch repetition or pitch commonality (the major component of 'sensory dissonance'. METHODOLOGY/PRINCIPAL FINDINGS: Two groups of subjects (musicians and nonmusicians were investigated with electroencephalography (EEG. Irregular chords elicited an early right anterior negativity (ERAN in the event-related brain potentials (ERPs. The ERAN had a latency of around 180 ms after the onset of the music-syntactically irregular chords, and had maximum amplitude values over right anterior electrode sites. CONCLUSIONS/SIGNIFICANCE: Because irregular chords were hardly detectable based on acoustical factors (such as pitch repetition and sensory dissonance, this ERAN effect reflects for the most part cognitive (not sensory components of regularity-based, music-syntactic processing. Our study represents a methodological advance compared to previous ERP-studies investigating the neural processing of music-syntactically irregular chords.

  9. Technical efficiency of Shiraz school of medicine in research and education domains: a data envelopment analysis.

    Science.gov (United States)

    Delavari, Somayeh; Rezaee, Rita; Hatam, Nahid; Delavari, Sajad

    2016-01-01

    Efficiency evaluation of universities and faculties is one of the tools that help managers to identify the departments' strengths and weakness. The main objective of the present research was to measure and compare the technical efficiency of Shiraz school of medicine departments using Data Envelopment Analysis (DEA) technique. This cross-sectional and retrospective study was performed on clinical and non-clinical departments in research and education domains over the period of 2006 to 2011. Different inputs and outputs were considered for research and educational domain separately. Efficiency was measured based on the observed optimal performance. Findings showed that pathology and anatomy departments achieved the score of 100 in technical efficiency in education during 2006 to 2011. During this period, parasitology, psychiatric and pediatrics department's achieved the score of 100 for technical efficiency in research domain. The lowest mean of relative educational efficiency belonged to orthopedic department; as to relative research efficiency, the lowest mean was shown in orthopedics and genetics departments. The mean technical efficiency of non-medical departments in education and research domain was 91.93 and 76.08, respectively, while the mean technical efficiency of the clinical department in educational and research fields was 91.02 and 82.23, respectively. Using multiple input and output in DEA technique provided a comprehensive evaluation of efficiency in Shiraz school of medicine departments. The DEA could successfully estimate the technical efficiency of the departments in research and educational fields. Moreover, the deficiency in each department was found; this could help them to plan for improvement.

  10. Domain Walls and Textured Vortices in a Two-Component Ginzburg-Landau Model

    DEFF Research Database (Denmark)

    Madsen, Søren Peder; Gaididei, Yu. B.; Christiansen, Peter Leth

    2005-01-01

    We look for domain wall and textured vortex solutions in a two-component Ginzburg-Landau model inspired by two-band superconductivity. The two-dimensional two-component model, with equal coherence lengths and no magnetic field, shows some interesting properties. In the absence of a Josephson type...... coupling between the two order parameters a ''textured vortex'' is found by analytical and numerical solution of the Ginzburg-Landau equations. With a Josephson type coupling between the two order parameters we find the system to split up in two domains separated by a domain wall, where the order parameter...

  11. Critical Components of Curriculum Development for Career and Technical Education Instructors in the United States

    Science.gov (United States)

    Wang, Victor C. X.

    2010-01-01

    Developing curriculum(s) requires instructors to take into several factors. These factors can be viewed as critical components of curriculum development for career and technical education (CTE) instructors. Without adequately addressing critical components such as curriculum history, curriculum theory, curriculum philosophies, curriculum…

  12. Domain-Specific Mappings as Conceptual Categorisers for Scientific and Technical Vocabularies

    Directory of Open Access Journals (Sweden)

    Pilar Durán-Escribano

    2017-10-01

    Full Text Available The analysis of metaphorical lexical units in science and technology provides evidence for their existence either as separate cases or as part of a corresponding conceptual metaphor. In conceptual metaphor, metaphorical expressions constitute productive patterns that unveil the mental mappings that support technical and scientific thought, proving to be a powerful device for conceptualization and a prolific driving force for language growth (Lakoff & Johnson, 1980. Although conceptual metaphor cannot account for all types of linguistic metaphor (Evans, 2013, in this paper we have focused on the former because it implies a systematic set of correspondences between different domains of science and technology supporting the role of conceptual metaphor as a powerful theory constitutive element. The study is based on the qualitative analysis of the metaphorical lexical units included in eight widely accepted specific dictionaries, totalling over 790.000 entries. Attention is focused on domain-specific mappings, in which not only the target but also the source domain pertain to scientific fields, and where the corresponding linguistic expressions keep their univocal meaning in each field. Thus, providing examples from two apparently unrelated fields, earth sciences and telecommunications engineering, the role of domain-specific mappings as conceptual categorisers is studied, underlying the different degrees of categorization involved in the building of new theories (Boyd, 1993, in definitions, and in the expression of new concepts.

  13. Simulated lumbar minimally invasive surgery educational model with didactic and technical components.

    Science.gov (United States)

    Chitale, Rohan; Ghobrial, George M; Lobel, Darlene; Harrop, James

    2013-10-01

    The learning and development of technical skills are paramount for neurosurgical trainees. External influences and a need for maximizing efficiency and proficiency have encouraged advancements in simulator-based learning models. To confirm the importance of establishing an educational curriculum for teaching minimally invasive techniques of pedicle screw placement using a computer-enhanced physical model of percutaneous pedicle screw placement with simultaneous didactic and technical components. A 2-hour educational curriculum was created to educate neurosurgical residents on anatomy, pathophysiology, and technical aspects associated with image-guided pedicle screw placement. Predidactic and postdidactic practical and written scores were analyzed and compared. Scores were calculated for each participant on the basis of the optimal pedicle screw starting point and trajectory for both fluoroscopy and computed tomographic navigation. Eight trainees participated in this module. Average mean scores on the written didactic test improved from 78% to 100%. The technical component scores for fluoroscopic guidance improved from 58.8 to 52.9. Technical score for computed tomography-navigated guidance also improved from 28.3 to 26.6. Didactic and technical quantitative scores with a simulator-based educational curriculum improved objectively measured resident performance. A minimally invasive spine simulation model and curriculum may serve a valuable function in the education of neurosurgical residents and outcomes for patients.

  14. The Use of Workforce Assessment as a Component of Career and Technical Education Program Evaluation

    Science.gov (United States)

    Bartlett, Kenneth R.; Schleif, Nicole L.; Bowen, Mauvalyn M.

    2011-01-01

    This research project examined the extent to which Career and Technical Education (CTE)-related programs use workforce needs assessment as a component of their evaluation activities. An employer perspective was used to develop a conceptual framework drawing on strategic human resource management theory. The extent and methods utilized for…

  15. Technical meeting on materials for in-vessel components of ITER

    International Nuclear Information System (INIS)

    Kalinin, G.; Barabash, V.

    2000-01-01

    The Technical meeting on materials for in-vessel components of ITER was held at the ITER Joint Work Site in Garching from 31 January to 4 February. The main objectives of the meetings were: 1. to summarize the requirements, 2. to review new data, 3. to discuss in detail the R and D program and to discuss the material assessment report

  16. Modern technical diagnostic system for the main components of powerful turbine generator

    International Nuclear Information System (INIS)

    Ezovit, G.P.; Uglyarenko, V.P.; Burlaka, S.I.; Goroz, N.I.; Orinin, S.E.; Komaritsa, V.N.; Zav'yalov, D.N.; Mazurenko, O.A.

    2011-01-01

    The modern diagnostic system to monitor the technical state of a powerful turbine generator is considered. This system permits the detection of defects in its main components and cooling system at the early stage of their development, prevention of damage and, as a consequence, emergency shutdown of nuclear power units

  17. Imaging ferroelectric domains via charge gradient microscopy enhanced by principal component analysis

    Directory of Open Access Journals (Sweden)

    Ehsan Nasr Esfahani

    2017-12-01

    Full Text Available Local domain structures of ferroelectrics have been studied extensively using various modes of scanning probes at the nanoscale, including piezoresponse force microscopy (PFM and Kelvin probe force microscopy (KPFM, though none of these techniques measure the polarization directly, and the fast formation kinetics of domains and screening charges cannot be captured by these quasi-static measurements. In this study, we used charge gradient microscopy (CGM to image ferroelectric domains of lithium niobate based on current measured during fast scanning, and applied principal component analysis (PCA to enhance the signal-to-noise ratio of noisy raw data. We found that the CGM signal increases linearly with the scan speed while decreases with the temperature under power-law, consistent with proposed imaging mechanisms of scraping and refilling of surface charges within domains, and polarization change across domain wall. We then, based on CGM mappings, estimated the spontaneous polarization and the density of surface charges with order of magnitude agreement with literature data. The study demonstrates that PCA is a powerful method in imaging analysis of scanning probe microscopy (SPM, with which quantitative analysis of noisy raw data becomes possible.

  18. The Twofold Multidimensionality of Academic Self-Concept: Domain Specificity and Separation between Competence and Affect Components

    Science.gov (United States)

    Arens, A. Katrin; Yeung, Alexander Seeshing; Craven, Rhonda G.; Hasselhorn, Marcus

    2011-01-01

    Academic self-concept is consistently proven to be multidimensional rather than unidimensional as it is domain specific in nature. However, each specific self-concept domain may be further separated into competence and affect components. This study examines the twofold multidimensionality of academic self-concept (i.e., its domain specificity and…

  19. Final Technical Report - Integrated Hydrogeophysical and Hydrogeologic Driven Parameter Upscaling for Dual-Domain Transport Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Shafer, John M

    2012-11-05

    The three major components of this research were: 1. Application of minimally invasive, cost effective hydrogeophysical techniques (surface and borehole), to generate fine scale (~1m or less) 3D estimates of subsurface heterogeneity. Heterogeneity is defined as spatial variability in hydraulic conductivity and/or hydrolithologic zones. 2. Integration of the fine scale characterization of hydrogeologic parameters with the hydrogeologic facies to upscale the finer scale assessment of heterogeneity to field scale. 3. Determination of the relationship between dual-domain parameters and practical characterization data.

  20. Simulated spinal cerebrospinal fluid leak repair: an educational model with didactic and technical components.

    Science.gov (United States)

    Ghobrial, George M; Anderson, Paul A; Chitale, Rohan; Campbell, Peter G; Lobel, Darlene A; Harrop, James

    2013-10-01

    In the era of surgical resident work hour restrictions, the traditional apprenticeship model may provide fewer hours for neurosurgical residents to hone technical skills. Spinal dura mater closure or repair is 1 skill that is infrequently encountered, and persistent cerebrospinal fluid leaks are a potential morbidity. To establish an educational curriculum to train residents in spinal dura mater closure with a novel durotomy repair model. The Congress of Neurological Surgeons has developed a simulation-based model for durotomy closure with the ongoing efforts of their simulation educational committee. The core curriculum consists of didactic training materials and a technical simulation model of dural repair for the lumbar spine. Didactic pretest scores ranged from 4/11 (36%) to 10/11 (91%). Posttest scores ranged from 8/11 (73%) to 11/11 (100%). Overall, didactic improvements were demonstrated by all participants, with a mean improvement between pre- and posttest scores of 1.17 (18.5%; P = .02). The technical component consisted of 11 durotomy closures by 6 participants, where 4 participants performed multiple durotomies. Mean time to closure of the durotomy ranged from 490 to 546 seconds in the first and second closures, respectively (P = .66), whereby the median leak rate improved from 14 to 7 (P = .34). There were also demonstrative technical improvements by all. Simulated spinal dura mater repair appears to be a potentially valuable tool in the education of neurosurgery residents. The combination of a didactic and technical assessment appears to be synergistic in terms of educational development.

  1. Pullback -Attractor of Nonautonomous Three-Component Reversible Gray-Scott System on Unbounded Domains

    Directory of Open Access Journals (Sweden)

    Anhui Gu

    2013-01-01

    Full Text Available The long time behavior of solutions of the nonautonomous three-components reversible Gray-Scott system defined on the entire space ℝn is studied when the external forcing terms are unbounded in a phase space. The existence of a pullback global attractor for the equation is established in L2ℝn3 and H1ℝn3, respectively. The pullback asymptotic compactness of solutions is proved by using uniform estimates on the tails of solutions on unbounded domains.

  2. Co-evolution of intelligent socio-technical systems modelling and applications in large scale emergency and transport domains

    CERN Document Server

    2013-01-01

    As the interconnectivity between humans through technical devices is becoming ubiquitous, the next step is already in the making: ambient intelligence, i.e. smart (technical) environments, which will eventually play the same active role in communication as the human players, leading to a co-evolution in all domains where real-time communication is essential. This topical volume, based on the findings of the Socionical European research project, gives equal attention to two highly relevant domains of applications: transport, specifically traffic, dynamics from the viewpoint of a socio-technical interaction and evacuation scenarios for large-scale emergency situations. Care was taken to investigate as much as possible the limits of scalability and to combine the modeling using complex systems science approaches with relevant data analysis.

  3. Structural studies of the activation of the two component receiver domain NTRC by multidimensional heteronuclear NMR

    Energy Technology Data Exchange (ETDEWEB)

    Nohaile, Michael James [Univ. of California, Berkeley, CA (United States). Dept. of Chemistry

    1996-05-01

    Multidimensional heteronuclear NMR spectroscopy was used to investigate the N-terminal domain of the transcriptional enhancer NTRC (NiTrogen Regulatory protein C). This domain belongs to the family of receiver domains of two-component regulatory systems involved in signal transduction. Phosphorylation of NTRC at D54 leads to an activated form of the molecule which stimulates transcription of genes involved in nitrogen regulation. Three and four dimensional NMR techniques were used to determine an intermediate resolution structure of the unphosphorylated, inactive form of the N-terminal domain of NTRC. The structure is comprised of five α-helices and a five-stranded β-sheet in a (β/α)5 topology. Analysis of the backbone dynamics of NTRC indicate that helix 4 and strand 5 are significantly more flexible than the rest of the secondary structure of the protein and that the loops making up the active site are flexible. The short lifetime of phospho-NTRC hampers the study of this form. However, conditions for determining the resonance assignments and, possibly, the three dimensional structure of phosphorylated NTRC have been obtained. Tentative assignments of the phosphorylated form indicate that the majority of the changes that NTRC experiences upon phosphorylation occur in helix 3, strand 4, helix 4, strand 5, and the loop between strand 5 and helix 5 (the 3445 face of NTRC) as well as near the site of phosphorylation. In order to examine a stable, activated form of the protein, constitutively active mutants of NTRC were investigated.

  4. Ubiquitous transient stagnant domain formation during thermal convection in a well-mixed two component fluid with large viscosity difference.

    Science.gov (United States)

    Kobayashi, Kazuya U; Kurita, Rei

    2017-10-11

    The formation of a transient stagnant domain in the presence of thermal convection was previously reported near the sol-gel transition temperature of a gelatin solution. The transient stagnant domain is observed near a critical Rayleigh number where a "roll" pattern is usually stable. It is important to understand the origin of the transient stagnant domain formation since it induces a large deformation of convection patterns; the nature of the formation of the transient stagnant domain remains unclear. Here, we observe thermal convection using several different fluids and find that stagnant domain formation is ubiquitous in two component mixtures. In addition, we find that difference in viscosity between the two components is crucial for transient stagnant domain formation, more so than the concentration gradient induced by the temperature gradient.

  5. Technical Needs for Prototypic Prognostic Technique Demonstration for Advanced Small Modular Reactor Passive Components

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, Ryan M.; Coble, Jamie B.; Hirt, Evelyn H.; Ramuhalli, Pradeep; Mitchell, Mark R.; Wootan, David W.; Berglin, Eric J.; Bond, Leonard J.; Henager, Charles H.

    2013-05-17

    This report identifies a number of requirements for prognostics health management of passive systems in AdvSMRs, documents technical gaps in establishing a prototypical prognostic methodology for this purpose, and describes a preliminary research plan for addressing these technical gaps. AdvSMRs span multiple concepts; therefore a technology- and design-neutral approach is taken, with the focus being on characteristics that are likely to be common to all or several AdvSMR concepts. An evaluation of available literature is used to identify proposed concepts for AdvSMRs along with likely operational characteristics. Available operating experience of advanced reactors is used in identifying passive components that may be subject to degradation, materials likely to be used for these components, and potential modes of degradation of these components. This information helps in assessing measurement needs for PHM systems, as well as defining functional requirements of PHM systems. An assessment of current state-of-the-art approaches to measurements, sensors and instrumentation, diagnostics and prognostics is also documented. This state-of-the-art evaluation, combined with the requirements, may be used to identify technical gaps and research needs in the development, evaluation, and deployment of PHM systems for AdvSMRs. A preliminary research plan to address high-priority research needs for the deployment of PHM systems to AdvSMRs is described, with the objective being the demonstration of prototypic prognostics technology for passive components in AdvSMRs. Greater efficiency in achieving this objective can be gained through judicious selection of materials and degradation modes that are relevant to proposed AdvSMR concepts, and for which significant knowledge already exists. These selections were made based on multiple constraints including the analysis performed in this document, ready access to laboratory-scale facilities for materials testing and measurement, and

  6. Technical Note: Introduction of variance component analysis to setup error analysis in radiotherapy

    International Nuclear Information System (INIS)

    Matsuo, Yukinori; Nakamura, Mitsuhiro; Mizowaki, Takashi; Hiraoka, Masahiro

    2016-01-01

    Purpose: The purpose of this technical note is to introduce variance component analysis to the estimation of systematic and random components in setup error of radiotherapy. Methods: Balanced data according to the one-factor random effect model were assumed. Results: Analysis-of-variance (ANOVA)-based computation was applied to estimate the values and their confidence intervals (CIs) for systematic and random errors and the population mean of setup errors. The conventional method overestimates systematic error, especially in hypofractionated settings. The CI for systematic error becomes much wider than that for random error. The ANOVA-based estimation can be extended to a multifactor model considering multiple causes of setup errors (e.g., interpatient, interfraction, and intrafraction). Conclusions: Variance component analysis may lead to novel applications to setup error analysis in radiotherapy.

  7. Technical Note: Introduction of variance component analysis to setup error analysis in radiotherapy.

    Science.gov (United States)

    Matsuo, Yukinori; Nakamura, Mitsuhiro; Mizowaki, Takashi; Hiraoka, Masahiro

    2016-09-01

    The purpose of this technical note is to introduce variance component analysis to the estimation of systematic and random components in setup error of radiotherapy. Balanced data according to the one-factor random effect model were assumed. Analysis-of-variance (anova)-based computation was applied to estimate the values and their confidence intervals (CIs) for systematic and random errors and the population mean of setup errors. The conventional method overestimates systematic error, especially in hypofractionated settings. The CI for systematic error becomes much wider than that for random error. The anova-based estimation can be extended to a multifactor model considering multiple causes of setup errors (e.g., interpatient, interfraction, and intrafraction). Variance component analysis may lead to novel applications to setup error analysis in radiotherapy.

  8. NEET-AMM Final Technical Report on Laser Direct Manufacturing (LDM) for Nuclear Power Components

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Scott [Lockheed Martin Corporation, Denver, CO (United States). Space Systems Company; Baca, Georgina [Lockheed Martin Corporation, Denver, CO (United States). Space Systems Company; O' Connor, Michael [Lockheed Martin Corporation, Denver, CO (United States). Space Systems Company

    2015-12-31

    Final technical report summarizes the program progress and technical accomplishments of the Laser Direct Manufacturing (LDM) for Nuclear Power Components project. A series of experiments varying build process parameters (scan speed and laser power) were conducted at the outset to establish the optimal build conditions for each of the alloys. Fabrication was completed in collaboration with Quad City Manufacturing Laboratory (QCML). The density of all sample specimens was measured and compared to literature values. Optimal build process conditions giving fabricated part densities close to literature values were chosen for making mechanical test coupons. Test coupons whose principal axis is on the x-y plane (perpendicular to build direction) and on the z plane (parallel to build direction) were built and tested as part of the experimental build matrix to understand the impact of the anisotropic nature of the process.. Investigations are described 316L SS, Inconel 600, 718 and 800 and oxide dispersion strengthed 316L SS (Yttria) alloys.

  9. Frequency domain synthetic aperture focusing technique for variable-diameter cylindrical components.

    Science.gov (United States)

    Jin, Haoran; Wu, Eryong; Han, Ye; Yang, Keji; Chen, Jian

    2017-09-01

    Ultrasonic non-destructive testing (UNDT) plays an important role in ensuring the quality of cylindrical components of equipment such as pipes and axles. As the acoustic beam width widens along propagation depths, the diffraction of acoustic wave becomes serious and the images of defects will be interfered with. To precisely evaluate the dimensions of defects and flaws concealed in components, the synthetic aperture focusing technique (SAFT) is introduced to enhance the image resolutions. Conventional SAFTs have been successfully implemented for the ultrasonic imaging of normal cylinders, while solutions for complex ones, such as variable-diameter cylinders, are still lacking. To overcome this problem, a frequency-domain SAFT for variable-diameter cylindrical components is proposed. This algorithm is mainly based on acoustic field extrapolation, which is modified from cylindrical phase shift migration with the aid of split-step Fourier. After a series of extrapolations, a high-resolution ultrasound image can be reconstructed using a particular imaging condition. According to the experimental results, the proposed method yields low side lobes and high resolutions for flat transducers. Its attainable angular resolution relies on the transducer diameter D and scanning radius R and approximates D/(2R).

  10. Co-existence of Gel and Fluid Lipid Domains in Single-component Phospholipid Membranes

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, Clare L [McMaster University; Barrett, M [McMaster University; Toppozini, L [McMaster University; Yamani, Zahra [Canadian Neutron Beam Centre, National Research Council, Chalk River Laboratorie; Kucerka, Norbert [Canadian Neutron Beam Centre and Comelius University (Slovakia); Katsaras, John [ORNL; Fragneto, Giovanna [Institut Laue-Langevin (ILL); Rheinstadter, Maikel C [McMaster University

    2012-01-01

    Lateral nanostructures in membranes, so-called rafts, are believed to strongly influence membrane properties and functions. The experimental observation of rafts has proven difficult as they are thought to be dynamic structures that likely fluctuate on nano- to microsecond time scales. Using neutron diffraction we present direct experimental evidence for the co-existence of gel and fluid lipid domains in a single-component phospholipid membrane made of DPPC as it undergoes its main phase transition. The coherence length of the neutron beam sets a lower limit for the size of structures that can be observed. Neutron coherence lengths between 30 and 242A used in this study were obtained by varying the incident neutron energy and the resolution of the neutron spectrometer. We observe Bragg peaks corresponding to co-existing nanometer sized structures, both in out-of-plane and in-plane scans, by tuning the neutron coherence length. During the main phase transition, instead of a continuous transition that shows a pseudo-critical behavior, we observe the co-existence of gel and fluid domains.

  11. Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145

    Energy Technology Data Exchange (ETDEWEB)

    Sampathkumar, Parthasarathy; Ozyurt, Sinem A.; Do, Johnny; Bain, Kevin T.; Dickey, Mark; Rodgers, Logan A.; Gheyi, Tarun; Sali, Andrej; Kim, Seung Joong; Phillips, Jeremy; Pieper, Ursula; Fernandez-Martinez, Javier; Franke, Josef D.; Martel, Anne; Tsuruta, Hiro; Atwell, Shane; Thompson, Devon A.; Emtage, J. Spencer; Wasserman, Stephen R.; Rout, Michael P.; Sauder, J. Michael; Burley, Stephen K. (SLAC); (Rockefeller); (UCSF); (Lilly)

    2012-04-30

    Nuclear pore complexes (NPCs) are large, octagonally symmetric dynamic macromolecular assemblies responsible for exchange of proteins and RNAs between the nucleus and cytoplasm. NPCs are made up of at least 456 polypeptides from {approx}30 distinct nucleoporins. Several of these components, sharing similar structural motifs, form stable subcomplexes that form a coaxial structure containing two outer rings (the nuclear and cytoplasmic rings), two inner rings, and a membrane ring. The yeast (Saccharomyces cerevisiae) Nup145 and its human counterpart are unique among the nucleoporins, in that they undergo autoproteolysis to generate functionally distinct proteins. The human counterpart of Nup145 is expressed as two alternatively spliced mRNA transcripts. The larger 190 kDa precursor undergoes post-translational autoproteolysis at the Phe863-Ser864 peptide bond yielding the 92 kDa Nup98 and the 96 kDa Nup96. The smaller 98 kDa precursor is also autoproteolysed at an analogous site giving 92 kDa Nup98-N and a 6 kDa C-terminal fragment, which may form a noncovalent complex. The yeast Nup145 precursor [Fig. 1(A)] contains twelve repeats of a 'GLFG' peptide motif (FG repeats) at its N-terminus, an internal autoproteolytic domain (a region of high conservation with the homologous yeast nucleoporins Nup110 and Nup116, neither of which undergo autoproteolysis), followed by the C-terminal domain. Various forms of the FG repeats are present in nearly half of all nucleoporins; they form intrinsically disordered regions implicated in gating mechanisms that control passage of macromolecules through NPCs. Nup145 undergoes autoproteolysis at the Phe605-Ser606 peptide bond to generate two functionally distinct proteins, Nup145N and Nup145C. Subsequently, Nup145C associates with six other proteins to form the heptameric Y-complex, a component of the outer rings of the NPC. Nup145N, on the other hand, can shuttle between the NPC and the nuclear interior. It has been suggested

  12. Three technical issues in fatigue damage assessment of nuclear power plant components

    International Nuclear Information System (INIS)

    Ware, A.G.; Shah, V.N.

    1991-01-01

    This paper addresses three technical issues that affect the fatigue damage assessment of nuclear power plant components: the effect of the environment on the fatigue life, the importance of the loading sequence in calculating the fatigue crack-initiation damage, and the adequacy of current inservice inspection requirements and methods to characterize fatigue cracks. The environmental parameters that affect the fatigue life of carbon and low alloy steel components are the sulphur content in the steel, the temperature, the amount of dissolved oxygen in the coolant, and the presence of oxidizing agents such as copper oxide. The occurrence of large-amplitude stress cycles early in a component's life followed by low-amplitude stress cycles may cause crack initiation at a cumulative usage factor less than 1.0. The current inservice inspection requirements include volumetric inspections of welds but not of some susceptible sites in the base metal. In addition, the conventional ultrasonic testing techniques need to be improved for reliable detection and accurate sizing of fatigue cracks. 28 refs., 4 figs., 1 tab

  13. Distinction between harmonic and structural components in ambient excitation tests using the time-frequency domain decomposition technique

    OpenAIRE

    Le, Thien-Phu; ARGOUL, Pierre

    2015-01-01

    The time-frequency domain decomposition technique has been proposed for modal identification in ambient vibration testing. In the presence of harmonic excitations, the modal identification process can provide not only structural modes but also non-structural ones relative to harmonic components. It is thus important to distinguish between them. In this study, by using the time-frequency domain decomposition technique, it is demonstrated that the distinction between non-structural harmonic com...

  14. Relationship between SPRY and B30.2 protein domains. Evolution of a component of immune defence?

    Science.gov (United States)

    Rhodes, David A; de Bono, Bernard; Trowsdale, John

    2005-01-01

    SPRY and B30.2 are homologous domains which can be identified in 11 protein families encoded in the human genome. These include cell surface receptors of the immunoglobulin super-family (BTNs), negative regulators of the JAK/STAT pathway (SOCS-box SSB1–4) and proteins encoded by the numerous TRIM genes. Collectively, proteins containing SPRY and B30.2 domains cover a wide range of functions, including regulation of cytokine signalling (SOCS), RNA metabolism (DDX1, hnRNPs), intracellular calcium release (RyR receptors), immunity to retroviruses (TRIM5alpha) as well as regulatory and developmental processes (HERC1, Ash2L). In order to clarify the evolutionary relationship between the two domains, we compiled a curated database of SPRY and B30.2-domain sequences. We show that while SPRY domains are evolutionarily ancient, B30.2 domains, found in BTN and TRIM proteins, are a more recent evolutionary adaptation, comprising the combination of SPRY with an additional domain, PRY. The combination of SPRY and PRY to produce B30.2 domains may have been selected and maintained as a component of immune defence. PMID:16313355

  15. Frequency Domain Computer Programs for Prediction and Analysis of Rail Vehicle Dynamics : Volume 1. Technical Report

    Science.gov (United States)

    1975-12-01

    Frequency domain computer programs developed or acquired by TSC for the analysis of rail vehicle dynamics are described in two volumes. Volume I defines the general analytical capabilities required for computer programs applicable to single rail vehi...

  16. Technical program to study the benefits of nonlinear analysis methods in LWR component designs. Technical report TR-3723-1

    International Nuclear Information System (INIS)

    Raju, P.P.

    1980-05-01

    This report summarizes the results of the study program to assess the benefits of nonlinear analysis methods in Light Water Reactor (LWR) component designs. The current study reveals that despite its increased cost and other complexities, nonlinear analysis is a practical and valuable tool for the design of LWR components, especially under ASME Level D service conditions (faulted conditions) and it will greatly assist in the evaluation of ductile fracture potential of pressure boundary components. Since the nonlinear behavior is generally a local phenomenon, the design of complex components can be accomplished through substructuring isolated localized regions and evaluating them in detail using nonlinear analysis methods

  17. Personalized Service Creation by Non-technical Users in the Homecare Domain

    NARCIS (Netherlands)

    Zarifi Eslami, Mohammed; Zarghami, Alireza; Sapkota, Brahmananda; van Sinderen, Marten J.

    One of the conditions for the successful introduction of ICT-based homecare services is to allow non-technical persons such as home nurses to personalize these services. We refer to this process of homecare service personalization as service tailoring. Service tailoring can be done by configuring

  18. Agreement Coefficients as Indices of Dependability for Domain-Referenced Tests. ACT Technical Bulletin No. 28.

    Science.gov (United States)

    Kane, Michael T.; Brennan, Robert L.

    A large number of seemingly diverse coefficients have been proposed as indices of dependability, or reliability, for domain-referenced and/or mastery tests. In this paper, it is shown that most of these indices are special cases of two generalized indices of agreement: one that is corrected for chance, and one that is not. The special cases of…

  19. A service component-based accounting and charging architecture to support interim mechanisms across multiple domains

    NARCIS (Netherlands)

    Le, M. van; Beijnum, B.J.F. van; Huitema, G.B.

    2004-01-01

    Today, telematics services are often compositions of different chargeable service components offered by different service providers. To enhance component-based accounting and charging, the service composition information is used to match with the corresponding charging structure of a service

  20. Probabilistic Structural Analysis Methods for select space propulsion system components (PSAM). Volume 3: Literature surveys and technical reports

    Science.gov (United States)

    1992-01-01

    The technical effort and computer code developed during the first year are summarized. Several formulations for Probabilistic Finite Element Analysis (PFEA) are described with emphasis on the selected formulation. The strategies being implemented in the first-version computer code to perform linear, elastic PFEA is described. The results of a series of select Space Shuttle Main Engine (SSME) component surveys are presented. These results identify the critical components and provide the information necessary for probabilistic structural analysis.

  1. Psychological readiness of heads of vocational technical schools to educational services’ marketing: components and conditions of development

    Directory of Open Access Journals (Sweden)

    Світлана Володимирівна Казакова

    2015-12-01

    Full Text Available The article deals with actual problem of psychological science – development of psychological readiness of heads of vocational technical schools to educational services’ marketing. The components of psychological readiness of heads to educational services’ marketing are determined. The conditions of development of readiness of heads to educational services’ marketing and its approbation in a post-graduate education are defined

  2. A Service Component-based Accounting and Charging Architecture to Support Interim Mechanisms across Multiple Domains

    NARCIS (Netherlands)

    Le, V.M.; van Beijnum, Bernhard J.F.; Huitema, G.B.

    Today, telematics services are o Aen compositions of different chargeable service components offered by different service providers. To enhance component-based accounting and charging, the service composition information is used to match with the corresponding charging structure of a service

  3. Recent assembly of an imprinted domain from non-imprinted components.

    Directory of Open Access Journals (Sweden)

    Robert W Rapkins

    2006-10-01

    Full Text Available Genomic imprinting, representing parent-specific expression of alleles at a locus, raises many questions about how--and especially why--epigenetic silencing of mammalian genes evolved. We present the first in-depth study of how a human imprinted domain evolved, analyzing a domain containing several imprinted genes that are involved in human disease. Using comparisons of orthologous genes in humans, marsupials, and the platypus, we discovered that the Prader-Willi/Angelman syndrome region on human Chromosome 15q was assembled only recently (105-180 million years ago. This imprinted domain arose after a region bearing UBE3A (Angelman syndrome fused with an unlinked region bearing SNRPN (Prader-Willi syndrome, which had duplicated from the non-imprinted SNRPB/B'. This region independently acquired several retroposed gene copies and arrays of small nucleolar RNAs from different parts of the genome. In their original configurations, SNRPN and UBE3A are expressed from both alleles, implying that acquisition of imprinting occurred after their rearrangement and required the evolution of a control locus. Thus, the evolution of imprinting in viviparous mammals is ongoing.

  4. University of Maryland component of the Center for Multiscale Plasma Dynamics: Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Dorland, William [University of Maryland

    2014-11-18

    The Center for Multiscale Plasma Dynamics (CMPD) was a five-year Fusion Science Center. The University of Maryland (UMD) and UCLA were the host universities. This final technical report describes the physics results from the UMD CMPD.

  5. Time-domain ultra-wideband radar, sensor and components theory, analysis and design

    CERN Document Server

    Nguyen, Cam

    2014-01-01

    This book presents the theory, analysis, and design of ultra-wideband (UWB) radar and sensor systems (in short, UWB systems) and their components. UWB systems find numerous applications in the military, security, civilian, commercial and medicine fields. This book addresses five main topics of UWB systems: System Analysis, Transmitter Design, Receiver Design, Antenna Design and System Integration and Test. The developments of a practical UWB system and its components using microwave integrated circuits, as well as various measurements, are included in detail to demonstrate the theory, analysis and design technique. Essentially, this book will enable the reader to design their own UWB systems and components. In the System Analysis chapter, the UWB principle of operation as well as the power budget analysis and range resolution analysis are presented. In the UWB Transmitter Design chapter, the design, fabrication and measurement of impulse and monocycle pulse generators are covered. The UWB Receiver Design cha...

  6. Modality and domain specific components in auditory and visual working memory tasks.

    Science.gov (United States)

    Lehnert, Günther; Zimmer, Hubert D

    2008-03-01

    In the tripartite model of working memory (WM) it is postulated that a unique part system-the visuo-spatial sketchpad (VSSP)-processes non-verbal content. Due to behavioral and neurophysiological findings, the VSSP was later subdivided into visual object and visual spatial processing, the former representing objects' appearance and the latter spatial information. This distinction is well supported. However, a challenge to this model is the question how spatial information from non-visual sensory modalities, for example the auditory one, is processed. Only a few studies so far have directly compared visual and auditory spatial WM. They suggest that the distinction of two processing domains--one for object and one for spatial information--also holds true for auditory WM, but that only a part of the processes is modality specific. We propose that processing in the object domain (the item's appearance) is modality specific, while spatial WM as well as object-location binding relies on modality general processes.

  7. Projects at the component development and integration facility. Quarterly technical progress report, April 1, 1994--June 30, 1994

    International Nuclear Information System (INIS)

    1994-01-01

    This quarterly technical progress report presents progress on the projects at the Component Development and Integration Facility (CDIF) during the third quarter of FY94. The CDIF is a major Department of Energy test facility in Butte, Montana, operated by MSE, Inc. Projects in progress include: Biomass Remediation Project; Heavy Metal-Contaminated Soil Project; MHD Shutdown; Mine Waste Technology Pilot Program; Plasma Projects; Resource Recovery Project; and Spray Casting Project

  8. Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy

    International Nuclear Information System (INIS)

    Fischer, B M; Walther, M; Jepsen, P Uhd

    2002-01-01

    The far-infrared dielectric function of a wide range of organic molecules is dominated by vibrations involving a substantial fraction of the atoms forming the molecule and motion associated with intermolecular hydrogen bond vibrations. Due to their collective nature such modes are highly sensitive to the intra- and intermolecular structure and thus provide a unique fingerprint of the conformational state of the molecule and effects of its environment. We demonstrate the use of terahertz time-domain spectroscopy (THz-TDS) for recording the far-infrared (0.5-4.0 THz) dielectric function of the four nucleobases and corresponding nucleosides forming the building blocks of deoxyribose nucleic acid (DNA). We observe numerous distinct spectral features with large differences between the molecules in both frequency-dependent absorption coefficient and index of refraction. Assisted by results from density-functional calculations we interpret the origin of the observed resonances as vibrations of hydrogen bonds between the molecules

  9. Independent component analysis of high-resolution imaging data identifies distinct functional domains

    DEFF Research Database (Denmark)

    Reidl, Juergen; Starke, Jens; Omer, David

    2007-01-01

    . Here we demonstrate that principal component analysis (PCA) followed by spatial independent component analysis (sICA), can be exploited to reduce the dimensionality of data sets recorded in the olfactory bulb and the somatosensory cortex of mice as well as the visual cortex of monkeys, without loosing...... latencies can be identified. This is shown for recordings of olfactory receptor neuron input measured with a calcium sensitive axon tracer and for network dynamics measured with the voltage sensitive dye RH 1838. In the somatosensory cortex, barrels responding to the stimulation of single whiskers can...... be automatically detected. In the visual cortex orientation columns can be extracted. In all cases artifacts due to movement, heartbeat or respiration were separated from the functional signal by sICA and could be removed from the data set. sICA is therefore a powerful technique for data compression, unbiased...

  10. Components Needed for the Design of a Sustainable Career and Technical Education Program

    Science.gov (United States)

    Lassiter, Vann Mizzelle

    2012-01-01

    As education has changed to meet the needs of society and has been shaped by the enactment of new laws, various aspects included under the massive umbrella of education have also changed to maintain momentum One such educational program is career and technical education (CTE). Changes to CTE have been made to continually meet the needs of all…

  11. Assessing soft skills components in science and technology programs within Malaysian Technical Universities

    OpenAIRE

    Kahirol Mohd Salleh; Nor Lisa Sulaiman; Mimi Mohaffyza Mohamad; Lai Chee Sern

    2017-01-01

    The workforce is a social environment where particular skills are essential in order for workers to perform well, have a competitive edge and succeed in their careers. A soft skill is one of the skills needed in every type of workplace setting. Soft skills include communication skills, collaboration skills, entrepreneurship, and others. Workplace need workers who are competent not only with technical skills but who also have soft skills. There is lack of literature discussion on the ...

  12. Alternative Feedstocks Program Technical and Economic Assessment: Thermal/Chemical and Bioprocessing Components

    Energy Technology Data Exchange (ETDEWEB)

    Bozell, J. J.; Landucci, R.

    1993-07-01

    This resource document on biomass to chemicals opportunities describes the development of a technical and market rationale for incorporating renewable feedstocks into the chemical industry in both a qualitative and quantitative sense. The term "renewable feedstock?s" can be defined to include a huge number of materials such as agricultural crops rich in starch, lignocellulosic materials (biomass), or biomass material recovered from a variety of processing wastes.

  13. A Synthetic Solution for Identification and Extraction of the Effective Microseismic Wave Component Using Decomposition on Time, Frequency, and Wavelet Coefficient Domains

    OpenAIRE

    Zhang, Mingwei; Meng, Qingbin; Liu, Shengdong; Shimada, Hideki

    2017-01-01

    To reduce noise components from original microseismic waves, a comprehensive fine signal processing approach using the integrated decomposition analysis of the wave duration, frequency spectrum, and wavelet coefficient domain was developed and implemented. Distribution regularities of the wave component and redundant noise on the frequency spectrum and the wavelet coefficient domain were first expounded. The frequency threshold and wavelet coefficient threshold were determined for the identif...

  14. Projects at the Component Development and Integration Facility. Quarterly technical progress report, January 1--March 31, 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    This quarterly technical progress report presents progress on several different projects at the Component Development and Integration Facility (CDIF) during the second quarter of FY93. The CDIF is a major US Department of Energy test facility in Butte, Montana, operated by MSE, Inc. Projects in progress include: MHD Proof-of-Concept Project; Mine Waste Technology Pilot Program; Plasma Furnace Projects for waste destruction; Resource Recovery Project; Sodium Sulfide/Ferrous Sulfate Project; Soil Washing Project for removal of radioactive materials; and Spray Casting Project.

  15. A Synthetic Solution for Identification and Extraction of the Effective Microseismic Wave Component Using Decomposition on Time, Frequency, and Wavelet Coefficient Domains

    Directory of Open Access Journals (Sweden)

    Mingwei Zhang

    2017-01-01

    Full Text Available To reduce noise components from original microseismic waves, a comprehensive fine signal processing approach using the integrated decomposition analysis of the wave duration, frequency spectrum, and wavelet coefficient domain was developed and implemented. Distribution regularities of the wave component and redundant noise on the frequency spectrum and the wavelet coefficient domain were first expounded. The frequency threshold and wavelet coefficient threshold were determined for the identification and extraction of the effective wave component. The frequency components between the reconstructed microseismic wave and the original measuring signal were compared. The noise elimination effect via the scale-changed domain decomposition was evaluated. Interaction between the frequency threshold and the wavelet coefficient threshold in the time domain was discussed. The findings reveal that tri-domain decomposition analysis achieves the precise identification and extraction of the effective microseismic wave component and improves the reliability of waves by eliminating the redundant noise. The frequency threshold and the wavelet coefficient threshold on a specific time window are two critical parameters that determine the degree of precision for the identification of the extracted wave component. This research involves development of the proposed integrated domain decomposition method and provides a diverse view on the fine processing of the microseismic signal.

  16. Cupulin is a zona pellucida-like domain protein and major component of the cupula from the inner ear.

    Science.gov (United States)

    Dernedde, Jens; Weise, Christoph; Müller, Eva-Christina; Hagiwara, Akira; Bachmann, Sebastian; Suzuki, Mamoru; Reutter, Werner; Tauber, Rudolf; Scherer, Hans

    2014-01-01

    The extracellular membranes of the inner ear are essential constituents to maintain sensory functions, the cupula for sensing torsional movements of the head, the otoconial membrane for sensing linear movements and accelerations like gravity, and the tectorial membrane in the cochlea for hearing. So far a number of structural proteins have been described, but for the gelatinous cupula precise data are missing. Here, we describe for the first time a major proteinogenic component of the cupula structure with an apparent molecular mass of 45 kDa from salmon. Analyses of respective peptides revealed highly conserved amino-acid sequences with identity to zona pellucida-like domain proteins. Immunohistochemistry studies localized the protein in the ampulla of the inner ear from salmon and according to its anatomical appearance we identified this glycoprotein as Cupulin. Future research on structure and function of zona pellucida-like domain proteins will enhance our knowledge of inner ear diseases, like sudden loss of vestibular function and other disturbances.

  17. The concept of the pedagogical system of the higher technical educational establishment: essential characteristics of its components

    Directory of Open Access Journals (Sweden)

    Ольга Петрівна Лучанінова

    2016-03-01

    Full Text Available The article discusses the essential characteristics of the components of the concept of modern educational system of higher technical educational institutions.We believe that the important role in organization of pedagogical system of the modern higher technical educational establishment belongs to qualitatively new approaches: humanistic and ideological, andragogical, facilitating, personal, cultural, diversificational, cordocentrism, systematic and activity approach, interactive.The concept of pedagogical system will be effective, if the main fundamentals of the Concept are included into the plans of pedagogical work of the higher educational establishments and their structural subdivisions; if the organizational and methodological facilities and studying and generalizing of the experience in organization of the pedagogical activities in the other higher educational establishments are prepared; if the scientific and methodological conferences, seminars, round-table discussion meetings, trainings and so on are organized and held; if we  promote active exchange of the theoretical and methodological aspects of the pedagogical system, of new approaches, forms and methods of the pedagogical activities; if we consider the questions of the Concept implementation at the meetings of the pedagogical work councils, educational and methodological commissions and the like.The offered authors Concept of the pedagogical system of the higher technical educational establishment should help the educators modulate the pedagogical process, involve various institutions and the society to the active participation in the educational and pedagogical process.

  18. Assessing soft skills components in science and technology programs within Malaysian Technical Universities

    Directory of Open Access Journals (Sweden)

    Kahirol Mohd Salleh

    2017-06-01

    Full Text Available The workforce is a social environment where particular skills are essential in order for workers to perform well, have a competitive edge and succeed in their careers. A soft skill is one of the skills needed in every type of workplace setting. Soft skills include communication skills, collaboration skills, entrepreneurship, and others. Workplace need workers who are competent not only with technical skills but who also have soft skills. There is lack of literature discussion on the perceptions of needed soft skills in the workplace. Therefore, this study aimed to close the gap in the literature concerning the perceptions of instructors and students in the area of soft skills especially in communication skills, collaboration skills, and entrepreneurship at the workplace. This study aims to decrease the divide in soft skills differences among instructors and students in higher learning institutions so that students have the opportunity to excel in their learning process. This study employs quantitative method specifically using survey as an instrument. The findings shows soft skills including communication, collaboration, and entrepreneurship skills are one of the aspects stressed by the students and instructors at higher learning institutions to ensure that graduates will be employable and competent in order to contribute to the nation development.

  19. TECHNICAL DESIGN NOTE: Three-component velocity measurement in microscale flows using time-resolved PIV

    Science.gov (United States)

    Erkan, N.; Shinohara, K.; Someya, S.; Okamoto, K.

    2008-05-01

    The measurement of a three-component (3C) velocity field in microfluidic devices with conventional techniques and conventional micro-PIV (particle image velocimetry) is still difficult due to limited optical access. Since Santiago et al (1998 Exp. Fluids 25 316-9), micro-PIV flow velocity measurements have remained mainly limited to 2C velocity vector field realizations. In this study, the third component of the velocity, i.e. out-of-plane velocity extraction from two-dimensional time-resolved (TR) micro-PIV images, is proposed. The method is based on PIV and performs cross-correlation (CC) peak height tracking inside the small ensembles of the TR-PIV flow images. This concept was verified basically by an experiment performed on a microscale fluid flow inside a 100 µm diameter inclined micro tube. Despite the inevitable background noise which affects the measurement negatively, the extracted steady-state depthwise velocity profile was in agreement with the analytical result.

  20. Security Hardened Cyber Components for Nuclear Power Plants: Phase I SBIR Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Franusich, Michael D. [SpiralGen, Inc., Pittsburgh, PA (United States)

    2016-03-18

    SpiralGen, Inc. built a proof-of-concept toolkit for enhancing the cyber security of nuclear power plants and other critical infrastructure with high-assurance instrumentation and control code. The toolkit is based on technology from the DARPA High-Assurance Cyber Military Systems (HACMS) program, which has focused on applying the science of formal methods to the formidable set of problems involved in securing cyber physical systems. The primary challenges beyond HACMS in developing this toolkit were to make the new technology usable by control system engineers and compatible with the regulatory and commercial constraints of the nuclear power industry. The toolkit, packaged as a Simulink add-on, allows a system designer to assemble a high-assurance component from formally specified and proven blocks and generate provably correct control and monitor code for that subsystem.

  1. Temperature extraction in Brillouin optical time-domain analysis sensors using principal component analysis based pattern recognition.

    Science.gov (United States)

    Azad, Abul Kalam; Khan, Faisal Nadeem; Alarashi, Waled Hussein; Guo, Nan; Lau, Alan Pak Tao; Lu, Chao

    2017-07-10

    We propose and experimentally demonstrate the use of principal component analysis (PCA) based pattern recognition to extract temperature distribution from the measured Brillouin gain spectra (BGSs) along the fiber under test (FUT) obtained by Brillouin optical time domain analysis (BOTDA) system. The proposed scheme employs a reference database consisting of relevant ideal BGSs with known temperature attributes. PCA is then applied to the BGSs in the reference database as well as to the measured BGSs so as to reduce their size by extracting their most significant features. Now, for each feature vector of the measured BGS, we determine its best match in the reference database comprised of numerous reduced-size feature vectors of the ideal BGSs. The known temperature attribute corresponding to the best-matched BGS in the reference database is then taken as the extracted temperature of the measured BGS. We analyzed the performance of PCA-based pattern recognition algorithm in detail and compared it with that of curve fitting method. The experimental results validate that the proposed technique can provide better accuracy, faster processing speed and larger noise tolerance for the measured BGSs. Therefore, the proposed PCA-based pattern recognition algorithm can be considered as an attractive method for extracting temperature distributions along the fiber in BOTDA sensors.

  2. A survey of HK, HPt, and RR domains and their organization in two-component systems and phosphorelay proteins of organisms with fully sequenced genomes

    Directory of Open Access Journals (Sweden)

    Baldiri Salvado

    2015-08-01

    Full Text Available Two Component Systems and Phosphorelays (TCS/PR are environmental signal transduction cascades in prokaryotes and, less frequently, in eukaryotes. The internal domain organization of proteins and the topology of TCS/PR cascades play an important role in shaping the responses of the circuits. It is thus important to maintain updated censuses of TCS/PR proteins in order to identify the various topologies used by nature and enable a systematic study of the dynamics associated with those topologies. To create such a census, we analyzed the proteomes of 7,609 organisms from all domains of life with fully sequenced and annotated genomes. To begin, we survey each proteome searching for proteins containing domains that are associated with internal signal transmission within TCS/PR: Histidine Kinase (HK, Response Regulator (RR and Histidine Phosphotranfer (HPt domains, and analyze how these domains are arranged in the individual proteins. Then, we find all types of operon organization and calculate how much more likely are proteins that contain TCS/PR domains to be coded by neighboring genes than one would expect from the genome background of each organism. Finally, we analyze if the fusion of domains into single TCS/PR proteins is more frequently observed than one might expect from the background of each proteome. We find 50 alternative ways in which the HK, HPt, and RR domains are observed to organize into single proteins. In prokaryotes, TCS/PR coding genes tend to be clustered in operons. 90% of all proteins identified in this study contain just one of the three domains, while 8% of the remaining proteins combine one copy of an HK, a RR, and/or an HPt domain. In eukaryotes, 25% of all TCS/PR proteins have more than one domain. These results might have implications for how signals are internally transmitted within TCS/PR cascades. These implications could explain the selection of the various designs in alternative circumstances.

  3. An Earth Observation Land Data Assimilation System for Data from Multiple Wavelength Domains: Water and Energy Balance Components

    Science.gov (United States)

    Quaife, T. L.; Davenport, I. J.; Lines, E.; Styles, J.; Lewis, P.; Gurney, R. J.

    2012-12-01

    Satellite observations offer a spatially and temporally synoptic data source for constraining models of land surface processes, but exploitation of these data for such purposes has been largely ad-hoc to date. In part this is because traditional land surface models, and hence most land surface data assimilation schemes, have tended to focus on a specific component of the land surface problem; typically either surface fluxes of water and energy or biogeochemical cycles such as carbon and nitrogen. Furthermore the assimilation of satellite data into such models tends to be restricted to a single wavelength domain, for example passive microwave, thermal or optical, depending on the problem at hand. The next generation of land surface schemes, such as the Joint UK Land Environment Simulator (JULES) and the US Community Land Model (CLM) represent a broader range of processes but at the expense of increasing overall model complexity and in some cases reducing the level of detail in specific processes to accommodate this. Typically, the level of physical detail used to represent the interaction of electromagnetic radiation with the surface is not sufficient to enable prediction of intrinsic satellite observations (reflectance, brightness temperature and so on) and consequently these are not assimilated directly into the models. A seemingly attractive alternative is to assimilate high-level products derived from satellite observations but these are often only superficially related to the corresponding variables in land surface models due to conflicting assumptions between the two. This poster describes the water and energy balance modeling components of a project funded by the European Space Agency to develop a data assimilation scheme for the land surface and observation operators to translate between models and the intrinsic observations acquired by satellite missions. The rationale behind the design of the underlying process model is to represent the physics of the

  4. Identification and classification of transient pulses observed in magnetometer array data by time-domain principal component analysis filtering

    Science.gov (United States)

    Kappler, Karl N.; Schneider, Daniel D.; MacLean, Laura S.; Bleier, Thomas E.

    2017-08-01

    A method for identification of pulsations in time series of magnetic field data which are simultaneously present in multiple channels of data at one or more sensor locations is described. Candidate pulsations of interest are first identified in geomagnetic time series by inspection. Time series of these "training events" are represented in matrix form and transpose-multiplied to generate time-domain covariance matrices. The ranked eigenvectors of this matrix are stored as a feature of the pulsation. In the second stage of the algorithm, a sliding window (approximately the width of the training event) is moved across the vector-valued time-series comprising the channels on which the training event was observed. At each window position, the data covariance matrix and associated eigenvectors are calculated. We compare the orientation of the dominant eigenvectors of the training data to those from the windowed data and flag windows where the dominant eigenvectors directions are similar. This was successful in automatically identifying pulses which share polarization and appear to be from the same source process. We apply the method to a case study of continuously sampled (50 Hz) data from six observatories, each equipped with three-component induction coil magnetometers. We examine a 90-day interval of data associated with a cluster of four observatories located within 50 km of Napa, California, together with two remote reference stations-one 100 km to the north of the cluster and the other 350 km south. When the training data contains signals present in the remote reference observatories, we are reliably able to identify and extract global geomagnetic signals such as solar-generated noise. When training data contains pulsations only observed in the cluster of local observatories, we identify several types of non-plane wave signals having similar polarization.

  5. Progress in the domain of emissions tracking and environment radioactivity monitoring - Proceedings of the technical days organised by the SFRP Environment Section

    International Nuclear Information System (INIS)

    Calmet, Dominique; Calvez, Marianne; Rivasseau, Corinne Cea; Monfort, Marguerite; Manificat, Guillaume; Pierrard, Olivier; Couvez, Celine; Masson, Olivier; Bruno, Valerie; Renaud, Philippe; Genova, Zhana; Reynal, Nathalie; Le Coz, Eric; Tchilian, Nathalie; Diana, Jean-Jacques; Beguinel, Philippe; Cortes, Pierre; Puydarrieux, Stephane; Brun, Thierry; Devin, Patrick; Clavel, Benoit; Hemidy, Pierre-Yves; Gontier, Gilles; Delloye, Thierry; Mailliat, Alain; Ferreri, Giovanni; LECLERC, Elisabeth

    2015-11-01

    The Environment Section of the French Society of Radiation Protection (SFRP) organized a technical meeting on the progress made in the domain of emissions tracking and environment radioactivity monitoring. This document brings together the abstracts and the presentations (slides) of the different talks given at the meeting: 1 - Environment monitoring at the global, national and local scale: historical overview (Dominique CALMET, CEA); 2 - Evolution of radioactivity monitoring in the environment from 1960 to the present day (Guillaume MANIFICAT, IRSN); 3 - Euratom's legal framework (Zhana GENOVA, CTE); 4 - Main regulatory changes during the last decade (Nathalie REYNAL, ASN); 5 - Progress of standardization works on radioactive effluent emissions control and environment monitoring (Philippe BEGUINEL, BNEN); 6 - From operators' self-monitoring to ASN's inspections: a many components control system (Eric LE COZ, ASN); 7 - Control of effluents and emissions management at CEA Centres (Marianne CALVEZ, CEA); 8 - Liquid and gaseous effluents of ITER experimental facility: description and impacts (Pierre CORTES, IO); 9 - Effluents and emissions management strategy at AREVA NC La Hague facility (Stephane PUYDARRIEUX, AREVA); 10 - Radioactive effluents from nuclear facilities ongoing deconstruction: from dimensioning to real effluents (Benoit CLAVEL, EDF); 11 - Radionuclides decontamination process for liquid effluents using micro-algae at the laboratory scale (Corinne RIVASSEAU, CEA); 12 - Radioactive effluents from nuclear medicine services: management, monitoring and impact measurement methods (Nathalie TCHILIAN, ASN); 13 - Evolution history of effluents management and environment monitoring at the Solvay La Rochelle site (Thierry DELLOYE, SOLVAY); 14 - Different international approaches in effluents management and monitoring: example of French and German gaseous effluents - regulation, analyses, accounting rules (Jean-Jacques DIANA, ASN); 15 - Environment

  6. SARA Reading Components Tests, RISE Forms: Technical Adequacy and Test Design, 2nd Edition. Research Report. ETS RR-15-32

    Science.gov (United States)

    Sabatini, John; Bruce, Kelly; Steinberg, Jonathan; Weeks, Jonathan

    2015-01-01

    This technical report describes the conceptual foundation and measurement properties of the Reading Inventory and Scholastic Evaluation (RISE). The RISE is a 6-subtest, Web-administered reading skills components battery. The theoretical and empirical foundations of each subtest in the battery are reviewed, as well as item designs. The results…

  7. Water chemistry and corrosion control of cladding and primary circuit components. Proceedings of a technical committee meeting

    International Nuclear Information System (INIS)

    1999-12-01

    Corrosion is the principal life limiting degradation mechanism in nuclear steam supply systems, especially taking into account the trends to increase fuel burnup, thermal rate and cycle length. Primary circuit components of water cooled power reactors have an impact on Zr-based alloys behaviour due to crud (primary circuit corrosion products) formation, transport and deposition on heat transfer surfaces. Crud deposits influence water chemistry, radiation and thermal hydraulic conditions near cladding surface, and by this way-Zr-based alloy corrosion. During the last decade, significant improvements were achieved in the reduction of the corrosion and dose rates by changing the cladding material for one more resistant to corrosion or by the improvement of water chemistry conditions. However, taking into account the above mentioned tendency for heavier fuel duties, corrosion and water chemistry, control will remain a serious task to work with for nuclear power plant operators and scientists, as well as development of generally accepted corrosion model of Zr-based alloys in a water environment in a new millennium. Upon the recommendation of the International Working Group on Water Reactor Fuel Performance and Technology, water chemistry and corrosion of cladding and primary circuit components are in the focus of the IAEA activities in the area of fuel technology and performance. At present the IAEA performs two co-ordinated research projects (CRPs): on On-line High Temperature Monitoring of Water Chemistry and Corrosion (WACOL) and on Activity Transport in Primary Circuits. Two CRPs deal with hydrogen and hydride degradation of the Zr-based alloys. A state-of-the-art review entitled: 'Waterside Corrosion of Zirconium Alloys in Nuclear Power Plants' was published in 1998. Technical Committee meetings on the subject were held in 1985 (Cadarache, France), 1989 (Portland, USA), 1993 (Rez, Czech Republic). During the last few years extensive exchange of experience in

  8. An Evaluation of the Science Education Component of the Cross River State Science and Technical Education Project

    Science.gov (United States)

    Ekuri, Emmanuel Etta

    2012-01-01

    The Cross River State Science and Technical Education Project was introduced in 1992 by edict number 9 of 20 December 1991, "Cross River State Science and Technical Education Board Edit, 20 December, 1991", with the aim of improving the quality of science teaching and learning in the state. As the success of the project depends…

  9. Bacillus subtilis Two-Component System Sensory Kinase DegS Is Regulated by Serine Phosphorylation in Its Input Domain

    DEFF Research Database (Denmark)

    Jers, Carsten; Kobir, Ahasanul; Søndergaard, Elsebeth Oline

    2011-01-01

    Bacillus subtilis two-component system DegS/U is well known for the complexity of its regulation. The cytosolic sensory kinase DegS does not receive a single predominant input signal like most two-component kinases, instead it integrates a wide array of metabolic inputs that modulate its activity......S phosphorylation at serine 76 and the level of DegU phosphorylation, establishing this post-translational modification as an additional trigger for this two-component system....

  10. Technical and economic working domains of industrial heat pumps: Part 1 - single stage vapour compression heat pumps

    DEFF Research Database (Denmark)

    Ommen, Torben Schmidt; Jensen, Jonas Kjær; Markussen, Wiebke Brix

    2015-01-01

    the constraints of available refrigeration equipment and a requirement of a positive net present value of the investment. Six heat pump systems were considered, corresponding to an upper limit of the sink temperature of 120 °C. For each set of heat sink and source temperatures the best available technology...... was determined. The results showed that four different heat pump systems propose the best available technology at different parts of the complete domain. Ammonia systems presented the best available technology at low sink outlet temperature. At high temperature difference between sink in- and outlet...

  11. Magnetic fusion energy plasma interactive and high heat flux components. Volume II. Technical assessment of the critical issues and problem areas in high heat flux materials and component development

    Energy Technology Data Exchange (ETDEWEB)

    Abdou, M.A.; Boyd, R.D.; Easor, J.R.; Gauster, W.B.; Gordon, J.D.; Mattas, R.F.; Morgan, G.D.; Ulrickson, M.A,; Watson, R.D.; Wolfer, W.G,

    1984-06-01

    A technical assessment of the critical issues and problem areas for high heat flux materials and components (HHFMC) in magnetic fusion devices shows these problems to be of critical importance for the successful operation of near-term fusion experiments and for the feasibility and attractiveness of long-term fusion reactors. A number of subgroups were formed to assess the critical HHFMC issues along the following major lines: (1) source conditions, (2) systems integration, (3) materials and processes, (4) thermal hydraulics, (5) thermomechanical response, (6) electromagnetic response, (7) instrumentation and control, and (8) test facilities. The details of the technical assessment are presented in eight chapters. The primary technical issues and needs for each area are highlighted.

  12. Magnetic fusion energy plasma interactive and high heat flux components. Volume II. Technical assessment of the critical issues and problem areas in high heat flux materials and component development

    International Nuclear Information System (INIS)

    Abdou, M.A.; Boyd, R.D.; Easor, J.R.

    1984-06-01

    A technical assessment of the critical issues and problem areas for high heat flux materials and components (HHFMC) in magnetic fusion devices shows these problems to be of critical importance for the successful operation of near-term fusion experiments and for the feasibility and attractiveness of long-term fusion reactors. A number of subgroups were formed to assess the critical HHFMC issues along the following major lines: (1) source conditions, (2) systems integration, (3) materials and processes, (4) thermal hydraulics, (5) thermomechanical response, (6) electromagnetic response, (7) instrumentation and control, and (8) test facilities. The details of the technical assessment are presented in eight chapters. The primary technical issues and needs for each area are highlighted

  13. A START-domain-containing protein is a novel marker of nervous system components of the sea cucumber Holothuria glaberrima.

    Science.gov (United States)

    Rosado-Olivieri, Edwin A; Ramos-Ortiz, Gibram A; Hernández-Pasos, Josué; Díaz-Balzac, Carlos A; Vázquez-Rosa, Edwin; Valentín-Tirado, Griselle; Vega, Irving E; García-Arrarás, José E

    2017-12-01

    One of the main challenges faced by investigators studying the nervous system of members of the phylum Echinodermata is the lack of markers to identify nerve cells and plexi. Previous studies have utilized an antibody, RN1, that labels most of the nervous system structures of the sea cucumber Holothuria glaberrima and other echinoderms. However, the antigen recognized by RN1 remained unknown. In the present work, the antigen has been characterized by immunoprecipitation, tandem mass spectrometry, and cDNA cloning. The RN1 antigen contains a START lipid-binding domain found in Steroidogenic Acute Regulatory (StAR) proteins and other lipid-binding proteins. Phylogenetic tree assembly showed that the START domain is highly conserved among echinoderms. We have named this antigen HgSTARD10 for its high sequence similarity to the vertebrate orthologs. Gene and protein expression analyses revealed an abundance of HgSTARD10 in most H. glaberrima tissues including radial nerve, intestine, muscle, esophagus, mesentery, hemal system, gonads and respiratory tree. Molecular cloning of HgSTARD10, consequent protein expression and polyclonal antibody production revealed the STARD10 ortholog as the antigen recognized by the RN1 antibody. Further characterization into this START domain-containing protein will provide important insights for the biochemistry, physiology and evolution of deuterostomes. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Semantic Meaning in Attitudinal Lexemes in the Domain of Kesenangan (Joy in Indonesian: An Analysis of Meaning Components and Lexical Relation

    Directory of Open Access Journals (Sweden)

    Prima Gusti Yanti

    2017-04-01

    Full Text Available The attitudinal lexeme on the domain of kesenangan in Indonesia language has not shown such clear meaning relationship, for both the common and diagnostic meaning of the lexemes. Those lexemes have such circular definitions, confusing upon their use. This study is conducted using a qualitative research approach employing content analysis technique. The aim of this study is to find out lexical relation and semantic meaning in attitudinal lexeme in the domain of kesenangan (joy in Indonesian language. Data is collected from seven Indonesian dictionaries, two magazines, five newspapers, and six literary works. All data is analyzed using a component analysis in the semantic theory. The research findings show that fourteen (14 lexemes (senang, nikmat, enak, puas, asyik, sukacita, ria, bangga, lega, bahagia, gembira, girang, riang, and ceria of attitudinal lexemes are related with the domain of kesenangan. The result shows that hyponymy and synonymy lexical relations occur in the domain of kesenangan. Synonymy relation consists of near-synonymy and propositional synonymy. In this case, absolute synonymy is not found.

  15. Operating experiences with heat-exchanging components of a semi-technical pilot plant for steam gasification of coal using heat from HTR

    International Nuclear Information System (INIS)

    Kirchhoff, R.; Heek, K.H. van

    1984-01-01

    within the framework of the PNP- Project, a semi-technical plant for the development of a process of coal gasification by means of nuclear heat was operated. Here gasification is for the first time implemented in a fluidized bed using heat of an electrically heated helium cycle at pressure up to 40 bar and temperatures normal for HTR. The plant serves for testing and developing various components as immersion heater, insulations, dosing devices, and for compiling sound data for further planning

  16. Component Reengineering Workshops

    DEFF Research Database (Denmark)

    Hansen, Klaus Marius; Christensen, Henrik Bærbak

    2004-01-01

    In mature domains, a number of competing product lines may emerge, and from the point of view of customers of such product lines, reengineering and reuse of assets across product lines from different vendors becomes important. To address this issue we present a low-cost approach, component...... reengineering workshops, for assessing reengineering costs of reusing components between different product lines. The approach works on the level of software architectures, and relies critically on input from various (technical) stakeholders. It has been validated through case studies that are also presented...

  17. Technical Note: Insertion of digital lesions in the projection domain for dual-source, dual-energy CT.

    Science.gov (United States)

    Ferrero, Andrea; Chen, Baiyu; Li, Zhoubo; Yu, Lifeng; McCollough, Cynthia

    2017-05-01

    To compare algorithms performing material decomposition and classification in dual-energy CT, it is desirable to know the ground truth of the lesion to be analyzed in real patient data. In this work, we developed and validated a framework to insert digital lesions of arbitrary chemical composition into patient projection data acquired on a dual-source, dual-energy CT system. A model that takes into account beam-hardening effects was developed to predict the CT number of objects with known chemical composition. The model utilizes information about the x-ray energy spectra, the patient/phantom attenuation, and the x-ray detector energy response. The beam-hardening model was validated on samples of iodine (I) and calcium (Ca) for a second-generation dual-source, dual-energy CT scanner for all tube potentials available and a wide range of patient sizes. The seven most prevalent mineral components of renal stones were modeled and digital stones were created with CT numbers computed for each patient/phantom size and x-ray energy spectra using the developed beam-hardening model. Each digital stone was inserted in the dual-energy projection data of a water phantom scanned on a dual-source scanner and reconstructed with the routine algorithms in use in our practice. The geometry of the forward projection for dual-energy data was validated by comparing CT number accuracy and high-contrast resolution of simulated dual-energy CT data of the ACR phantom with experimentally acquired data. The beam-hardening model and forward projection method accurately predicted the CT number of I and Ca over a wide range of tube potentials and phantom sizes. The images reconstructed after the insertion of digital kidney stones were consistent with the images reconstructed from the scanner, and the CT number ratios for different kidney stone types were consistent with data in the literature. A sample application of the proposed tool was also demonstrated. A framework was developed and validated

  18. Results from the electro-optic sensors domain of the materials and components for missiles innovation and technology partnership (phase 1)

    Science.gov (United States)

    Bray, Mark E.; Shears, Robert A.

    2013-10-01

    The Materials and Components for Missiles Innovation and Technology Partnership (ITP) is a research programme supporting research for guided weapons at Technology Readiness Levels 1 to 4. The Anglo-French initiative is supported by the DGA and the MoD, with matched funding from industry. A major objective is to foster projects which partner UK and French universities, SMEs and larger companies. The first projects started in January 2008 and the first phase completed in spring 2013. Providing funding is secured, the next phase of the programme is due to start later in 2013. Selex ES leads Domain 3 of the MCM-ITP which develops Electro-Optic sensor technology. In collaboration with DGA, MoD and MBDA, the prime contractor, we identified 4 key objectives for the first ITP phase and focussed resources on achieving these. The objectives were to enable better imagery, address operationally stressing scenarios, provide low overall through life cost and improve active and semi-active sensors Nine normal projects and one ITP innovation fund project have been supported within the domain. The technology providers have included 3 SMEs and 8 research centres from both the United Kingdom and France. Highlights of the projects are included. An outline of the priorities for the domain for the new phase ise provided and we encourage organisations with suitable technology to contact us to get involved.

  19. Magnetic fusion energy plasma interactive and high heat flux components. Volume I. Technical assessment of the critical issues and problem areas in the plasma materials interaction field

    International Nuclear Information System (INIS)

    Conn, R.W.; Gauster, W.B.; Heifetz, D.; Marmar, E.; Wilson, K.L.

    1984-01-01

    A technical assessment of the critical issues and problem areas in the field of plasma materials interactions (PMI) in magnetic fusion devices shows these problems to be central for near-term experiments, for intermediate-range reactor devices including D-T burning physics experiments, and for long-term reactor machines. Critical technical issues are ones central to understanding and successful operation of existing and near-term experiments/reactors or devices of great importance for the long run, i.e., ones which will require an extensive, long-term development effort and thus should receive attention now. Four subgroups were formed to assess the critical PMI issues along four major lines: (1) PMI and plasma confinement physics experiments; (2) plasma-edge modelling and theory; (3) surface physics; and (4) materials technology for in-vessel components and the first wall. The report which follows is divided into four major sections, one for each of these topics

  20. Magnetic fusion energy plasma interactive and high heat flux components. Volume I. Technical assessment of the critical issues and problem areas in the plasma materials interaction field

    Energy Technology Data Exchange (ETDEWEB)

    Conn, R.W.; Gauster, W.B.; Heifetz, D.; Marmar, E.; Wilson, K.L. (eds.)

    1984-01-01

    A technical assessment of the critical issues and problem areas in the field of plasma materials interactions (PMI) in magnetic fusion devices shows these problems to be central for near-term experiments, for intermediate-range reactor devices including D-T burning physics experiments, and for long-term reactor machines. Critical technical issues are ones central to understanding and successful operation of existing and near-term experiments/reactors or devices of great importance for the long run, i.e., ones which will require an extensive, long-term development effort and thus should receive attention now. Four subgroups were formed to assess the critical PMI issues along four major lines: (1) PMI and plasma confinement physics experiments; (2) plasma-edge modelling and theory; (3) surface physics; and (4) materials technology for in-vessel components and the first wall. The report which follows is divided into four major sections, one for each of these topics.

  1. Two Components of Aversive Memory in Drosophila, Anesthesia-Sensitive and Anesthesia-Resistant Memory, Require Distinct Domains Within the Rgk1 Small GTPase.

    Science.gov (United States)

    Murakami, Satoshi; Minami-Ohtsubo, Maki; Nakato, Ryuichiro; Shirahige, Katsuhiko; Tabata, Tetsuya

    2017-05-31

    Multiple components have been identified that exhibit different stabilities for aversive olfactory memory in Drosophila These components have been defined by behavioral and genetic studies and genes specifically required for a specific component have also been identified. Intermediate-term memory generated after single cycle conditioning is divided into anesthesia-sensitive memory (ASM) and anesthesia-resistant memory (ARM), with the latter being more stable. We determined that the ASM and ARM pathways converged on the Rgk1 small GTPase and that the N-terminal domain-deleted Rgk1 was sufficient for ASM formation, whereas the full-length form was required for ARM formation. Rgk1 is specifically accumulated at the synaptic site of the Kenyon cells (KCs), the intrinsic neurons of the mushroom bodies, which play a pivotal role in olfactory memory formation. A higher than normal Rgk1 level enhanced memory retention, which is consistent with the result that Rgk1 suppressed Rac-dependent memory decay; these findings suggest that rgk1 bolsters ASM via the suppression of forgetting. We propose that Rgk1 plays a pivotal role in the regulation of memory stabilization by serving as a molecular node that resides at KC synapses, where the ASM and ARM pathway may interact. SIGNIFICANCE STATEMENT Memory consists of multiple components. Drosophila olfactory memory serves as a fundamental model with which to investigate the mechanisms that underlie memory formation and has provided genetic and molecular means to identify the components of memory, namely short-term, intermediate-term, and long-term memory, depending on how long the memory lasts. Intermediate memory is further divided into anesthesia-sensitive memory (ASM) and anesthesia-resistant memory (ARM), with the latter being more stable. We have identified a small GTPase in Drosophila , Rgk1, which plays a pivotal role in the regulation of olfactory memory stability. Rgk1 is required for both ASM and ARM. Moreover, N

  2. The Hybrid Design: Integrating the Human and Technical Components of Just-In-Time Knowledge Management Systems

    Directory of Open Access Journals (Sweden)

    Nabie Y. Conteh

    2011-06-01

    Full Text Available This paper explores the right balance of human and technical resources in the design of Just-in-Time knowledge delivery. It also examines and analyzes the case study: “Teltech: The business of Knowledge Management” by Davenport. It further attempts to depict the characteristics of the hybrid. The paper describes how the hybrid can be applied to Just-In-Time knowledge delivery. It also seeks to analyze and explore its interplay with knowledge splits with a view to designing Just-In- Time Knowledge Management. These include: “tacit versus explicit knowledge”, “in-process” versus “after action” documentation, “process-centered versus product-centered approach”, “knowledge versus information” and the “culture of sharing versus hoarding.”

  3. Technical Letter Report, An Evaluation of Ultrasonic Phased Array Testing for Reactor Piping System Components Containing Dissimilar Metal Welds, JCN N6398, Task 2A

    Energy Technology Data Exchange (ETDEWEB)

    Diaz, Aaron A.; Cinson, Anthony D.; Crawford, Susan L.; Anderson, Michael T.

    2009-11-30

    Research is being conducted for the U.S. Nuclear Regulatory Commission at the Pacific Northwest National Laboratory to assess the effectiveness and reliability of advanced nondestructive examination (NDE) methods for the inspection of light-water reactor components. The scope of this research encom¬passes primary system pressure boundary materials including dissimilar metal welds (DMWs), cast austenitic stainless steels (CASS), piping with corrosion-resistant cladding, weld overlays, inlays and onlays, and far-side examinations of austenitic piping welds. A primary objective of this work is to evaluate various NDE methods to assess their ability to detect, localize, and size cracks in steel components that challenge standard and/or conventional inspection methodologies. This interim technical letter report provides a summary of a technical evaluation aimed at assessing the capabilities of phased-array (PA) ultrasonic testing (UT) methods as applied to the inspection of small-bore DMW components that exist in the reactor coolant systems (RCS) of pressurized water reactors (PWRs). Operating experience and events such as the circumferential cracking in the reactor vessel nozzle-to-RCS hot leg pipe at V.C. Summer nuclear power station, identified in 2000, show that in PWRs where primary coolant water (or steam) are present under normal operation, Alloy 82/182 materials are susceptible to pressurized water stress corrosion cracking. The extent and number of occurrences of DMW cracking in nuclear power plants (domestically and internationally) indicate the necessity for reliable and effective inspection techniques. The work described herein was performed to provide insights for evaluating the utility of advanced NDE approaches for the inspection of DMW components such as a pressurizer surge nozzle DMW, a shutdown cooling pipe DMW, and a ferritic (low-alloy carbon steel)-to-CASS pipe DMW configuration.

  4. Technical Letter Report, An Evaluation of Ultrasonic Phased Array Testing for Reactor Piping System Components Containing Dissimilar Metal Welds, JCN N6398, Task 2A

    International Nuclear Information System (INIS)

    Diaz, Aaron A.; Cinson, Anthony D.; Crawford, Susan L.; Anderson, Michael T.

    2009-01-01

    Research is being conducted for the U.S. Nuclear Regulatory Commission at the Pacific Northwest National Laboratory to assess the effectiveness and reliability of advanced nondestructive examination (NDE) methods for the inspection of light-water reactor components. The scope of this research encompasses primary system pressure boundary materials including dissimilar metal welds (DMWs), cast austenitic stainless steels (CASS), piping with corrosion-resistant cladding, weld overlays, inlays and onlays, and far-side examinations of austenitic piping welds. A primary objective of this work is to evaluate various NDE methods to assess their ability to detect, localize, and size cracks in steel components that challenge standard and/or conventional inspection methodologies. This interim technical letter report provides a summary of a technical evaluation aimed at assessing the capabilities of phased-array (PA) ultrasonic testing (UT) methods as applied to the inspection of small-bore DMW components that exist in the reactor coolant systems (RCS) of pressurized water reactors (PWRs). Operating experience and events such as the circumferential cracking in the reactor vessel nozzle-to-RCS hot leg pipe at V.C. Summer nuclear power station, identified in 2000, show that in PWRs where primary coolant water (or steam) are present under normal operation, Alloy 82/182 materials are susceptible to pressurized water stress corrosion cracking. The extent and number of occurrences of DMW cracking in nuclear power plants (domestically and internationally) indicate the necessity for reliable and effective inspection techniques. The work described herein was performed to provide insights for evaluating the utility of advanced NDE approaches for the inspection of DMW components such as a pressurizer surge nozzle DMW, a shutdown cooling pipe DMW, and a ferritic (low-alloy carbon steel)-to-CASS pipe DMW configuration.

  5. Proposal for the Award of Two Contracts for the Technical Services for Work on Components of CERN Particle Accelerators and High Energy Physics Experiments

    CERN Document Server

    2003-01-01

    This document concerns the award of two contracts for the technical services for work on components of CERN particle accelerators and high energy physics experiments. Following a market survey carried out among 73 firms in fourteen Member States, a call for tenders (IT-3156/SPL) was sent on 4 November 2002 to three consortia in four Member States. By the closing date, CERN had received tenders from the three consortia. The Finance Committee is invited to agree to the negotiation of two contracts with: 1) the consortium SERCO FACILITIES MANAGEMENT (NL) - GERARD PERRIER INDUSTRIE (FR) - INEO ALPES (FR), the lowest bidder, for approximately 55% of the technical services for work on components of CERN particle accelerators and high energy physics experiments, for an initial period of five years and for a total amount not exceeding 37 435 270 euros (54 902 500 Swiss francs), subject to revision for inflation from 1 January 2005. The contract will include options for two one-year extensions beyond the initial five-...

  6. Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63 Transcription through TEA Domain (TEAD) Transcription Factor*

    Science.gov (United States)

    Valencia-Sama, Ivette; Zhao, Yulei; Lai, Dulcie; Janse van Rensburg, Helena J.; Hao, Yawei; Yang, Xiaolong

    2015-01-01

    Transcriptional co-activator with a PDZ binding domain (TAZ) is a WW domain-containing transcriptional co-activator and a core component of an emerging Hippo signaling pathway that regulates organ size, tumorigenesis, metastasis, and drug resistance. TAZ regulates these biological functions by up-regulating downstream cellular genes through transactivation of transcription factors such as TEAD and TTF1. To understand the molecular mechanisms underlying TAZ-induced tumorigenesis, we have recently performed a gene expression profile analysis by overexpressing TAZ in mammary cells. In addition to the TAZ-up-regulated genes that were confirmed in our previous studies, we identified a large number of cellular genes that were down-regulated by TAZ. In this study, we have confirmed these down-regulated genes (including cytokines, chemokines, and p53 gene family members) as bona fide downstream transcriptional targets of TAZ. By using human breast and lung epithelial cells, we have further characterized ΔNp63, a p53 gene family member, and shown that TAZ suppresses ΔNp63 mRNA, protein expression, and promoter activity through interaction with the transcription factor TEAD. We also show that TEAD can inhibit ΔNp63 promoter activity and that TAZ can directly interact with ΔNp63 promoter-containing TEAD binding sites. Finally, we provide functional evidence that down-regulation of ΔNp63 by TAZ may play a role in regulating cell migration. Altogether, this study provides novel evidence that the Hippo component TAZ can function as a co-repressor and regulate biological functions by negatively regulating downstream cellular genes. PMID:25995450

  7. Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63 Transcription through TEA Domain (TEAD) Transcription Factor.

    Science.gov (United States)

    Valencia-Sama, Ivette; Zhao, Yulei; Lai, Dulcie; Janse van Rensburg, Helena J; Hao, Yawei; Yang, Xiaolong

    2015-07-03

    Transcriptional co-activator with a PDZ binding domain (TAZ) is a WW domain-containing transcriptional co-activator and a core component of an emerging Hippo signaling pathway that regulates organ size, tumorigenesis, metastasis, and drug resistance. TAZ regulates these biological functions by up-regulating downstream cellular genes through transactivation of transcription factors such as TEAD and TTF1. To understand the molecular mechanisms underlying TAZ-induced tumorigenesis, we have recently performed a gene expression profile analysis by overexpressing TAZ in mammary cells. In addition to the TAZ-up-regulated genes that were confirmed in our previous studies, we identified a large number of cellular genes that were down-regulated by TAZ. In this study, we have confirmed these down-regulated genes (including cytokines, chemokines, and p53 gene family members) as bona fide downstream transcriptional targets of TAZ. By using human breast and lung epithelial cells, we have further characterized ΔNp63, a p53 gene family member, and shown that TAZ suppresses ΔNp63 mRNA, protein expression, and promoter activity through interaction with the transcription factor TEAD. We also show that TEAD can inhibit ΔNp63 promoter activity and that TAZ can directly interact with ΔNp63 promoter-containing TEAD binding sites. Finally, we provide functional evidence that down-regulation of ΔNp63 by TAZ may play a role in regulating cell migration. Altogether, this study provides novel evidence that the Hippo component TAZ can function as a co-repressor and regulate biological functions by negatively regulating downstream cellular genes. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  8. Development of a train-to-proficiency curriculum for the technical skills component of the fundamentals of endoscopic surgery exam.

    Science.gov (United States)

    Gearhart, Susan; Marohn, Michael; Ngamruengphong, Saowanee; Adrales, Gina; Owodunni, Oluwafemi; Duncan, Kim; Petrusa, Emil; Lipsett, Pamela

    2018-01-08

    The demonstration of competency in endoscopy is required prior to obtaining American Board of Surgery Certification. To demonstrate competency, the resident must pass a national high-stakes cognitive test and a technical skills exam on a virtual reality simulator. The purpose of this preliminary study was to design a proficiency-based endoscopy simulation curriculum to meet this competency requirement. This is a mixed methods prospective cohort study at a single academic medical institution. Prior to taking the national exam, surgery residents were required to participate in a skills lab and demonstrate proficiency on 10 simulation tasks. Proficiency was based on time and percent of objects targeted/mucosa seen. Simulation practice time, number of task repetitions to proficiency, and prior endoscopic experience were recorded. Resident's self-reported confidence scores in endoscopic skills prior to and following simulation lab training were obtained. From January 1, 2016 through August 1, 2017, 20 surgical residents (8 PGY2, 8 PGY3, 4 PGY4) completed both a faculty-supervised endoscopy skills lab and independent learning with train-to-proficiency simulation tasks. Median overall simulator time per resident was 306 min (IQR: 247-405 min). Median overall time to proficiency in all tasks was 235 min (IQR: 208-283 min). The median time to proficiency decreased with increasing PGY status (r = 0.4, P = 0.05). There was no correlation between prior real-time endoscopic experience and time to proficiency. Reported confidence in endoscopic skills increased significantly from mean of 5.75 prior to 7.30 following the faculty-supervised endoscopy skills lab (P = 0.0002). All 20 residents passed the national exam. In this preliminary study, a train-to-proficiency curriculum in endoscopy improved surgical resident's confidence in their endoscopic skills and 100% of residents passed the FES technical skills test on their first attempt. Our findings also indicate

  9. Relationship Between Changes in Pulse Pressure and Frequency Domain Components of Heart Rate Variability During Short-Term Left Ventricular Pacing in Patients with Cardiac Resynchronization Therapy.

    Science.gov (United States)

    Urbanek, Bożena; Ruta, Jan; Kudryński, Krzysztof; Ptaszyński, Paweł; Klimczak, Artur; Wranicz, Jerzy Krzysztof

    2016-06-15

    BACKGROUND The aim of the study was to explore the relationship between changes in pulse pressure (PP) and frequency domain heart rate variability (HRV) components caused by left ventricular pacing in patients with implanted cardiac resynchronization therapy (CRT). MATERIAL AND METHODS Forty patients (mean age 63±8.5 years) with chronic heart failure (CHF) and implanted CRT were enrolled in the study. The simultaneous 5-minute recording of beat-to-beat arterial systolic and diastolic blood pressure (SBP and DBP) by Finometer and standard electrocardiogram with CRT switched off (CRT/0) and left ventricular pacing (CRT/LV) was performed. PP (PP=SBP-DBP) and low- and high-frequency (LF and HF) HRV components were calculated, and the relationship between these parameters was analyzed. RESULTS Short-term CRT/LV in comparison to CRT/0 caused a statistically significant increase in the values of PP (P<0.05), LF (P<0.05), and HF (P<0.05). A statistically significant correlation between ΔPP and ΔHF (R=0.7384, P<0.05) was observed. The ΔHF of 6 ms2 during short-term CRT/LV predicted a PP increase of ≥10% with 84.21% sensitivity and 85.71% specificity. CONCLUSIONS During short-term left ventricular pacing in patients with CRT, a significant correlation between ΔPP and ΔHF was observed. ΔHF ≥6 ms2 may serve as a tool in the selection of a suitable site for placement of a left ventricular lead.

  10. THE CATALYTIC DOMAIN OF THE DIHYDROLIPOYL TRANSACETYLASE COMPONENT OF THE PYRUVATE-DEHYDROGENASE COMPLEX FROM AZOTOBACTER-VINELANDII AND ESCHERICHIA-COLI - EXPRESSION, PURIFICATION, PROPERTIES AND PRELIMINARY-X-RAY ANALYSIS

    NARCIS (Netherlands)

    SCHULZE, E; WESTPHAL, AH; OBMOLOVA, G; MATTEVI, A; HOL, WGJ; DEKOK, A

    1991-01-01

    Partial sequences of the dihydrolipoyl transacetylase component (E2p) of the pyruvate dehydrogenase complex from Azotobacter vinelandii and Escherichia coli, containing the catalytic domain, were cloned in pUC plasmids and over-expressed in E. coli TG2. A high expression of a homogeneous protein was

  11. Domains and domain loss

    DEFF Research Database (Denmark)

    Haberland, Hartmut

    2005-01-01

    politicians and in the media, especially in the discussion whether some languages undergo ‘domain loss’ vis-à-vis powerful international languages like English. An objection that has been raised here is that domains, as originally conceived, are parameters of language choice and not properties of languages...... not described in terms of domains, and recent research e.g. about the multilingual communities in the Danish-German border area seems to confirm this....

  12. Magnetic Fusion Energy Plasma Interactive and High Heat Flux Components: Volume 5, Technical assessment of critical issues in the steady state operation of fusion confinement devices

    International Nuclear Information System (INIS)

    1988-01-01

    Critical issues for the steady state operation of plasma confinement devices exist in both the physics and technology fields of fusion research. Due to the wide range and number of these issues, this technical assessment has focused on the crucial issues associated with the plasma physics and the plasma interactive components. The document provides information on the problem areas that affect the design and operation of a steady state ETR or ITER type confinement device. It discusses both tokamaks and alternative concepts, and provides a survey of existing and planned confinement machines and laboratory facilities that can address the identified issues. A universal definition of steady state operation is difficult to obtain. From a physics point of view, steady state is generally achieved when the time derivatives approach zero and the operation time greatly exceeds the characteristic time constants of the device. Steady state operation for materials depends on whether thermal stress, creep, fatigue, radiation damage, or power removal are being discussed. For erosion issues, the fluence and availability of the machine for continuous operation are important, assuming that transient events such as disruptions do not limit the component lifetimes. The panel suggests, in general terms, that steady state requires plasma operation from 100 to 1000 seconds and an availability of more than a few percent, which is similar to the expectations for an ETR type device. The assessment of critical issues for steady state operation is divided into four sections: physics issues; technology issues; issues in alternative concepts; and devices and laboratory facilities that can address these problems

  13. Magnetic Fusion Energy Plasma Interactive and High Heat Flux Components: Volume 5, Technical assessment of critical issues in the steady state operation of fusion confinement devices

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    Critical issues for the steady state operation of plasma confinement devices exist in both the physics and technology fields of fusion research. Due to the wide range and number of these issues, this technical assessment has focused on the crucial issues associated with the plasma physics and the plasma interactive components. The document provides information on the problem areas that affect the design and operation of a steady state ETR or ITER type confinement device. It discusses both tokamaks and alternative concepts, and provides a survey of existing and planned confinement machines and laboratory facilities that can address the identified issues. A universal definition of steady state operation is difficult to obtain. From a physics point of view, steady state is generally achieved when the time derivatives approach zero and the operation time greatly exceeds the characteristic time constants of the device. Steady state operation for materials depends on whether thermal stress, creep, fatigue, radiation damage, or power removal are being discussed. For erosion issues, the fluence and availability of the machine for continuous operation are important, assuming that transient events such as disruptions do not limit the component lifetimes. The panel suggests, in general terms, that steady state requires plasma operation from 100 to 1000 seconds and an availability of more than a few percent, which is similar to the expectations for an ETR type device. The assessment of critical issues for steady state operation is divided into four sections: physics issues; technology issues; issues in alternative concepts; and devices and laboratory facilities that can address these problems.

  14. Mobile sequences in the pyruvate dehydrogenase complex, the E2 component, the catalytic domain and the 2-oxogluturate dehydrogenase complex of Azotobacter vinelandii, as detected by 600 MHz 1H-NMR spectroscopy

    International Nuclear Information System (INIS)

    Hanemaaijer, R.; Vervoort, J.; Westphal, A.H.; Kok, A. de.; Veeger, C.

    1988-01-01

    600 MHz 1 H-NMR spectroscopy demonstrates that the pyruvate dehydrogenase complex of Azotobacter vinelandii contains regions of the polypeptide chain with intramolecular mobility. This mobility is located in the E 2 component and can probably be ascribed to alanine-proline-rich regions that link the lipoyl sibdiomains to each other as well as to the E 1 and E 3 binding domain. In the catalytic domain of E 2 which is thought to form a compact, rigid core, also conformational flexibility is observed. It is conceivable that the N-terminal region of the catalytic domain, which contains many alanine residues, is responsible for the observed mobility. In the low-field region of the 1 H-NMR spectrum of E 2 specific resonances are found, which can be ascribed to mobile phenylalanine, histidine and/or tyrosine residues which are located in the E 1 and E 3 binding domain that links the lipoyl domain to the catalytic domain. In the 1 H-NMR spectrum of the intact complex, these resonances cannot be observed, indicating a decreased mobility of the E 1 and E 3 binding domain. (author). 24 refs.; 2 figs

  15. 1H, 13C, and 15N resonance assignments of an enzymatically active domain from the catalytic component (CDTa, residues 216-420) of a binary toxin from Clostridium difficile.

    Science.gov (United States)

    Roth, Braden M; Godoy-Ruiz, Raquel; Varney, Kristen M; Rustandi, Richard R; Weber, David J

    2016-04-01

    Clostridium difficile is a bacterial pathogen and is the most commonly reported source of nosocomial infection in industrialized nations. Symptoms of C. difficile infection (CDI) include antibiotic-associated diarrhea, pseudomembranous colitis, sepsis and death. Over the last decade, rates and severity of hospital infections in North America and Europe have increased dramatically and correlate with the emergence of a hypervirulent strain of C. difficile characterized by the presence of a binary toxin, CDT (C. difficile toxin). The binary toxin consists of an enzymatic component (CDTa) and a cellular binding component (CDTb) that together form the active binary toxin complex. CDTa harbors a pair of structurally similar but functionally distinct domains, an N-terminal domain (residues 1-215; (1-215)CDTa) that interacts with CDTb and a C-terminal domain (residues 216-420; (216-420)CDTa) that harbors the intact ADP-ribosyltransferase (ART) active site. Reported here are the (1)H, (13)C, and (15)N backbone resonance assignments of the 23 kDa, 205 amino acid C-terminal enzymatic domain of CDTa, termed (216-420)CDTa. These NMR resonance assignments for (216-420)CDTa represent the first for a family of ART binary toxins and provide the framework for detailed characterization of the solution-state protein structure determination, dynamic studies of this domain, as well as NMR-based drug discovery efforts.

  16. 1HN, 13C, and 15N Resonance Assignments of the CDTb-Interacting Domain (CDTaBID) from the Clostridium difficile Binary Toxin Catalytic Component (CDTa, residues 1–221)

    Science.gov (United States)

    Roth, Braden M.; Varney, Kristen M.; Rustandi, Richard R.; Weber, David J.

    2016-01-01

    Once considered a relatively harmless bacterium, Clostridium difficile has become a major concern for healthcare facilities, now the most commonly reported hospital-acquired pathogen. C. difficile infection (CDI) is usually contracted when the normal gut microbiome is compromised by antibiotic therapy, allowing the opportunistic pathogen to grow and produce its toxins. The severity of infection ranges from watery diarrhea and abdominal cramping to pseudomembranous colitis, sepsis, or death. The past decade has seen a marked increase in the frequency and severity of CDI among industrialized nations owing directly to the emergence of a highly virulent C. difficile strain, NAP1. Along with the large Clostridial toxins expressed by non-epidemic strains, C. difficile NAP1 produces a binary toxin, CDT (C. difficile transferase). As the name suggests, CDT is a two-component toxin comprised of an ADP-ribosyltransferase (ART) component (CDTa) and a cell-binding/translocation component (CDTb) that function to destabilize the host cytoskeleton by covalent modification of actin monomers. Central to the mechanism of binary toxin-induced pathogenicity is the formation of CDTa/CDTb complexes at the cell surface. From the perspective of CDTa, this interaction is mediated by the N-terminal domain (residues 1–215) and is spatially and functionally independent of ART activity, which is located in the C-terminal domain (residues 216–420). Here we report the 1HN, 13C, and 15N backbone resonance assignments of a 212 amino acid, ~23 kDa N-terminal CDTb-interacting domain (CDTaBID) construct by heteronuclear NMR spectroscopy. These NMR assignments represent the first component coordination domain for a family of Clostridium or Bacillus species harboring ART activity. Our assignments lay the foundation for detailed solution state characterization of structure-function relationships, toxin complex formation, and NMR-based drug discovery efforts. PMID:27351891

  17. Training and technical assistance for compliance with beverage and physical activity components of New York City's regulations for early child care centers.

    Science.gov (United States)

    Kakietek, Jakub; Dunn, Lillian; O'Dell, Sarah Abood; Jernigan, Jan; Kettel Khan, Laura

    2014-10-16

    In 2006, the New York City Department of Health and Mental Hygiene (DOHMH) passed regulations for child care centers that established standards for beverages provided to children and set a minimum amount of time for daily physical activity. DOHMH offered several types of training and technical assistance to support compliance with the regulations. This article analyzes the association between training and technical assistance provided and compliance with the regulations in a sample of 174 group child care centers. Compliance was measured by using a site inventory of beverages stored on premises and a survey of centers' teachers regarding the amount of physical activity provided. Training and technical assistance measures were based on the DOHMH records of training and technical assistance provided to the centers in the sample and on a survey of center directors. Ordinal logistic regression was used to assess the association between training and technical assistance measures and compliance with the regulations. Measures of training related to physical activity the center received: the number of staff members who participated in Sport, Play and Active Recreation for Kids (SPARK) and other training programs in which a center participated were associated with better compliance with the physical activity regulations. Neither training nor technical assistance were associated with compliance with the regulations related to beverages. Increased compliance with regulations pertaining to physical activity was not related to compliance with beverage regulations. Future trainings should be targeted to the specific regulation requirements to increase compliance.

  18. Training and Technical Assistance for Compliance With Beverage and Physical Activity Components of New York City’s Regulations for Early Child Care Centers

    Science.gov (United States)

    Dunn, Lillian; O’Dell, Sarah Abood; Jernigan, Jan; Kettel Khan, Laura

    2014-01-01

    Introduction In 2006, the New York City Department of Health and Mental Hygiene (DOHMH) passed regulations for child care centers that established standards for beverages provided to children and set a minimum amount of time for daily physical activity. DOHMH offered several types of training and technical assistance to support compliance with the regulations. This article analyzes the association between training and technical assistance provided and compliance with the regulations in a sample of 174 group child care centers. Methods Compliance was measured by using a site inventory of beverages stored on premises and a survey of centers’ teachers regarding the amount of physical activity provided. Training and technical assistance measures were based on the DOHMH records of training and technical assistance provided to the centers in the sample and on a survey of center directors. Ordinal logistic regression was used to assess the association between training and technical assistance measures and compliance with the regulations. Results Measures of training related to physical activity the center received: the number of staff members who participated in Sport, Play and Active Recreation for Kids (SPARK) and other training programs in which a center participated were associated with better compliance with the physical activity regulations. Neither training nor technical assistance were associated with compliance with the regulations related to beverages. Conclusion Increased compliance with regulations pertaining to physical activity was not related to compliance with beverage regulations. Future trainings should be targeted to the specific regulation requirements to increase compliance. PMID:25321628

  19. Expertise development and technical assistance: critical components of the autonomous photovoltaic systems stability; Capacitacao e assistencia tecnica: componentes criticos na sustentabilidade de sistemas fotovoltaicos autonomos

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Heitor S.; Eck, Myriam; Silva, Gerson F.; Silva, Quezia F.; Pimentel, Ricardo B.; Guido, Rusangela R.; Pereira, Cristiane A.; Araujo, Kassia M. [Pernambuco Univ., Recife, PE (Brazil). Dept. de Engenharia Eletrica e Sistemas de Potencia. Nucleo de Apoio a Projetos de Energias Renovaveis]. E-mail: naper@npd.ufpe.br

    2000-07-01

    Implementing a rural electrification program with photovoltaic solar technology is a highly complex task since it implies in anticipating and solving problems, where multiple aspects (technical, economic, social, political and managerial) are intertwined. From the analysis of countries which have programs for the dissemination of the photovoltaic technology, like Thailand, Ecuador, Argentina, Bolivia, Peru, Mexico, The Philippines, Indonesia, Sri Lanka, Dominican Republic among others, the relevancy of the users participation in those programs becomes quite evident. This is very different from the traditional electrification process through wire networks. Two factors are critical for the success of those programs. Firstly, we consider the technical capacitation and technical assistance. The capacitation of a diverse set of actors, users (appropriate handling), technicians (solar electricians), managers from user associations (technical, financial and administrative management), plays a fundamental role for the assurance of a reasonable functioning of the photovoltaic solar systems, i.e., the assurance of a good electric service. The other determinant factor is the sustainability of the autonomous photovoltaic systems. Two levels of maintenance are defined: predictive and corrective. In this work we describe actions developed in the direction of the technical assistance and capacitation (broad sense) for the PERESF (Program for the Solar Electrification with Photovoltaic Solar Energy), managed by NAPER (Nucleo de Apoio a Projetos de Energias Renovaveis), in semi-arid region of the state of Pernambuco. (author)

  20. Crystallization and preliminary X-ray diffraction analysis of the P3 RNA domain of yeast ribonuclease MRP in a complex with RNase P/MRP protein components Pop6 and Pop7.

    Science.gov (United States)

    Perederina, Anna; Esakova, Olga; Quan, Chao; Khanova, Elena; Krasilnikov, Andrey S

    2010-01-01

    Eukaryotic ribonucleases P and MRP are closely related RNA-based enzymes which contain a catalytic RNA component and several protein subunits. The roles of the protein subunits in the structure and function of eukaryotic ribonucleases P and MRP are not clear. Crystals of a complex that included a circularly permuted 46-nucleotide-long P3 domain of the RNA component of Saccharomyces cerevisiae ribonuclease MRP and selenomethionine derivatives of the shared ribonuclease P/MRP protein components Pop6 (18.2 kDa) and Pop7 (15.8 kDa) were obtained using the sitting-drop vapour-diffusion method. The crystals belonged to space group P4(2)22 (unit-cell parameters a = b = 127.2, c = 76.8 A, alpha = beta = gamma = 90 degrees ) and diffracted to 3.25 A resolution.

  1. Modelling of Context: Designing Mobile Systems from Domain-Dependent Models

    DEFF Research Database (Denmark)

    Nielsen, Peter Axel; Stage, Jan

    2009-01-01

    Modelling of domain-dependent aspects is a key prerequisite for the design of software for mobile systems. Most mobile systems include a more or less advanced model of selected aspects of the domain in which they are used. This paper discusses the creation of such a model and its relevance...... for technical design of a mobile software system. Conventional approaches to modelling of context focus either on the application domain or the problem domain. These approaches are presented and their relevance for technical design of software for mobile systems is discussed. The paper also reports from...... an empirical study where a methodology that combines both of these approaches was introduced and employed for modelling of the domain-dependent aspects that were relevant for the design of a software component in a mobile telephone. The empirical study was conducted in two companies that produce software...

  2. Study of structure of technical and tactical activity of high class hockey players of different line by the method of main component

    Directory of Open Access Journals (Sweden)

    Oleksiy Mikhnov

    2014-10-01

    Full Text Available Purpose: to study the factor structure of technical and tactical actions of hockey players of high qualification of different playing line of business. Material and methods: for the leadthrough of analysis of competition activity information of technical and tactical actions of hockey players was used NHL. Competition activity was in general complication analysed more than 800 hockey players of different line of business. Methods were used: pedagogical supervisions and analysis of competition activity, analysis of data of the special scientific-methodical literature, an analysis of data is the Internet, methods of mathematical statistics. Results: information is presented in relation to the specific of competition activity of hockey players of high class of different line of business in a match. The factor structure of technical and tactical activity of hockey players, executing in the command of function of extreme forward, central forward, defender and goalkeeper is set. for the players of line of attack most meaningfulness was had factors, related to the attack of gate of competitor, for defenders are power single combats, defense of gate and selection of puck, for a goalkeeper the most meaningful factor is characterized by efficiency of reflection of throws on a gate. Conclusions: the exposed features are in realization of technical and tactical actions the hockey players of high class of different playing line of business, it is necessary certainly to take into account in the process of estimation and control.

  3. Building the DAML Electronic Commerce Domain

    National Research Council Canada - National Science Library

    Anyiwo, David

    2001-01-01

    The project captured additional functional and technical requirements for collaboration and exchange in the electronics industry's value chain, and refined the eCommerce domain ontology requirements...

  4. Technical presentation

    CERN Multimedia

    FI Department

    2008-01-01

    RADIOSPARES, the leading catalogue distributor of components (electronic, electrical, automation, etc.) and industrial supplies will be at CERN on Friday 3 October 2008 (Main Building, Room B, from 9.00 a.m. to 3.00 p.m.) to introduce its new 2008/2009 catalogue. This will be the opportunity for us to present our complete range of products in more detail: 400 000 part numbers available on our web site (Radiospares France, RS International, extended range of components from other manufacturers); our new services: quotations, search for products not included in the catalogue, SBP products (Small Batch Production: packaging in quantities adapted to customers’ requirements); partnership with our focus manufacturers; demonstration of the on-line purchasing tool implemented on our web site in conjunction with CERN. RADIOSPARES will be accompanied by representatives of FLUKE and TYCO ELECTRONICS, who will make presentations, demonstrate materials and answer any technical questio...

  5. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    Overview From a technical perspective, CMS has been in “beam operation” state since 6th November. The detector is fully closed with all components operational and the magnetic field is normally at the nominal 3.8T. The UXC cavern is normally closed with the radiation veto set. Access to UXC is now only possible during downtimes of LHC. Such accesses must be carefully planned, documented and carried out in agreement with CMS Technical Coordination, Experimental Area Management, LHC programme coordination and the CCC. Material flow in and out of UXC is now strictly controlled. Access to USC remains possible at any time, although, for safety reasons, it is necessary to register with the shift crew in the control room before going down.It is obligatory for all material leaving UXC to pass through the underground buffer zone for RP scanning, database entry and appropriate labeling for traceability. Technical coordination (notably Stephane Bally and Christoph Schaefer), the shift crew and run ...

  6. A Study on Dielectric Properties of Cadmium Sulfide-Zinc Sulfide Core-Shell Nanocomposites for Application as Nanoelectronic Filter Component in the Microwave Domain

    Science.gov (United States)

    Devi, Jutika; Datta, Pranayee

    2018-03-01

    Complex permittivities of cadmium sulfide (CdS), zinc sulfide (ZnS), and of cadmium sulfide-zinc sulfide (CdS/ZnS) core-shell nanoparticles embedded in a polyvinyl alcohol matrix (PVA) were measured in liquid phase using a VectorNetwork Analyzer in the frequency range of 500 MHz-10 GHz. These nanocomposites are modeled as an embedded capacitor, and their electric field distribution and polarization have been studied using COMSOL Multiphysics software. By varying the thickness of the shell and the number of inclusions, the capacitance values were estimated. It was observed that CdS, ZnS and CdS/ZnS core-shell nanoparticles embedded in a polyvinyl alcohol matrix show capacitive behavior. There is a strong influence of the dielectric properties in the capacitive behavior of the embedded nanocapacitor. The capping matrix, position and filling factors of nanoinclusions all affect the capacitive behavior of the tested nanocomposites. Application of the CdS, ZnS and CdS/ZnS core-shell nanocomposite as the passive low-pass filter circuit has also been investigated. From the present study, it has been found that CdS/ZnS core-shell nanoparticles embedded in PVA matrix are potential structures for application as nanoelectronic filter components in different areas of communication.

  7. Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain

    Science.gov (United States)

    van Roon, Anne-Marie M.; Obayashi, Eiji; Sposito, Benedetta; Newman, Andrew J.; Séraphin, Bertrand

    2017-01-01

    Spliceosomal proteins Hsh49p and Cus1p are components of SF3b, which together with SF3a, Msl1p/Lea1p, Sm proteins, and U2 snRNA, form U2 snRNP, which plays a crucial role in pre-mRNA splicing. Hsh49p, comprising two RRMs, forms a heterodimer with Cus1p. We determined the crystal structures of Saccharomyces cerevisiae full-length Hsh49p as well as its RRM1 in complex with a minimal binding region of Cus1p (residues 290–368). The structures show that the Cus1 fragment binds to the α-helical surface of Hsh49p RRM1, opposite the four-stranded β-sheet, leaving the canonical RNA-binding surface available to bind RNA. Hsh49p binds the 5′ end region of U2 snRNA via RRM1. Its affinity is increased in complex with Cus1(290-368)p, partly because an extended RNA-binding surface forms across the protein–protein interface. The Hsh49p RRM1–Cus1(290-368)p structure fits well into cryo-EM density of the Bact spliceosome, corroborating the biological relevance of our crystal structure. PMID:28348170

  8. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    Tuesday 30 March TECHNICAL TRAINING SEMINAR From 9:00 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Technical conferences: 09:00 - 12:00 Data acquisition systems on PCs. Industrial measurement and control techniques. 13:00 - 16:00 Advanced LabVIEW software and PXI instrumentation. Measuring instruments and system components for teststand automation. Introductory courses: 09:00 - 12:00 DIAdem: Data analysis and presentation 13:00 - 16:00 Data acquisition with LabVIEW Language: English and French Free special seminar. Registration is recommended with National Instruments Switzerland (please sp...

  9. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    Tuesday 30 March TECHNICAL TRAINING SEMINAR From 9:00 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Technical conferences: 09:00 - 12:00 Data acquisition systems on PCs. Industrial measurement and control techniques. 13:00 - 16:00 Advanced LabVIEW software and PXI instrumentation. Measuring instruments and system components for teststand automation. Introductory courses: 09:00 - 12:00 DIAdem: Data analysis and presentation 13:00 - 16:00 Data acquisition with LabVIEW Language: English and French Free special seminar. Registration is recommended with National Instruments Swi...

  10. Prognostics for Microgrid Components

    Science.gov (United States)

    Saxena, Abhinav

    2012-01-01

    Prognostics is the science of predicting future performance and potential failures based on targeted condition monitoring. Moving away from the traditional reliability centric view, prognostics aims at detecting and quantifying the time to impending failures. This advance warning provides the opportunity to take actions that can preserve uptime, reduce cost of damage, or extend the life of the component. The talk will focus on the concepts and basics of prognostics from the viewpoint of condition-based systems health management. Differences with other techniques used in systems health management and philosophies of prognostics used in other domains will be shown. Examples relevant to micro grid systems and subsystems will be used to illustrate various types of prediction scenarios and the resources it take to set up a desired prognostic system. Specifically, the implementation results for power storage and power semiconductor components will demonstrate specific solution approaches of prognostics. The role of constituent elements of prognostics, such as model, prediction algorithms, failure threshold, run-to-failure data, requirements and specifications, and post-prognostic reasoning will be explained. A discussion on performance evaluation and performance metrics will conclude the technical discussion followed by general comments on open research problems and challenges in prognostics.

  11. A research project to develop and evaluate a technical education component on materials technology for orientation to space-age technology

    Science.gov (United States)

    Jacobs, J. A.

    1976-01-01

    A project was initiated to develop, implement, and evaluate a prototype component for self-pacing, individualized instruction on basic materials science. Results of this project indicate that systematically developed, self-paced instruction provides an effective means for orienting nontraditional college students and secondary students, especially minorities, to both engineering technology and basic materials science. In addition, students using such a system gain greater chances for mastering subject matter than with conventional modes of instruction.

  12. Characterization and management of radioactive sodium and other reactor components as input data for the decommissioning of liquid metal-cooled fast reactors. A compilation of data produced of data produced by members of the IAEA technical working group on fast reactors (TWG-FR) at two consultancies and one technical committee meeting. Working material

    International Nuclear Information System (INIS)

    2002-01-01

    A number of liquid metal cooled fast reactors (LMFRs) are in operation and, some have already been shut down; other reactors will reach the end of their design lifetime in a few years and become candidates for decommissioning. It is unfortunate that little consideration was devoted to decommissioning of reactors at the plant design and construction stage. It is with this focus that the Technical Working Group on Fast Reactors (TWGFR) recommended that the IAEA organize the exchange of information on LMFRs decommissioning technology. It was pointed out that the decommissioning of small sodium-cooled reactors has shown that there are two basic differences between thermal and fast reactors decommissioning: on the one side, the treatment and disposal of radioactive sodium coolant, and on the other side, the management of reactor components, for which the structural materials are activated in depth by fast neutrons. To this end, a Technical Committee Meeting on Sodium Removal and Disposal from LMFRs in Normal Operation and in the framework of Decommissioning (Aix-en-Provence, France, November 1997) and two Consultancies on Decommissioning of the Kazakh BN-350 LMFR (Vienna, Austria, October 1996; Obninsk, Russian Federation, February 1998) were convened by the IAEA. These Meetings brought together a group of experts from France, Russia, Kazakhstan, the UK, and the USA to exchange information on, and to review current technical knowledge and experience in the management of radioactive coolant and reactor components following closing of LMFRs, as well as their design features and operating experience relevant for decommissioning procedures. The report provides general and detailed information on activation characteristics of the primary coolant; treatment and disposal of the spent sodium; removal of the residual sodium deposits and decontamination; the activation characteristics of the reactor components and the management of the latter. The recurring theme is finding

  13. Separating Cognitive and Content Domains in Mathematical Competence

    Science.gov (United States)

    Harks, Birgit; Klieme, Eckhard; Hartig, Johannes; Leiss, Dominik

    2014-01-01

    The present study investigates the empirical separability of mathematical (a) content domains, (b) cognitive domains, and (c) content-specific cognitive domains. There were 122 items representing two content domains (linear equations vs. theorem of Pythagoras) combined with two cognitive domains (modeling competence vs. technical competence)…

  14. Technical Note: On the impact of the incident electron beam energy on the primary dose component of flattening filter free photon beams.

    Science.gov (United States)

    Kuess, Peter; Georg, Dietmar; Palmans, Hugo; Lechner, Wolfgang

    2016-08-01

    For commercially available linear accelerators (Linacs), the electron energies of flattening filter free (FFF) and flattened (FF) beams are either identical or the electron energy of the FFF beam is increased to match the percentage depth dose curve (PDD) of the FF beam (in reference geometry). This study focuses on the primary dose components of FFF beams for both kinds of settings, studied on the same Linac. The measurements were conducted on a VersaHD Linac (Elekta, Crawley, UK) for both FF and FFF beams with nominal energies of 6 and 10 MV. In the clinical setting of the VersaHD, the energy of FFFM (Matched) beams is set to match the PDDs of the FF beams. In contrast the incident electron beam of the FFFU beam was set to the same energy as for the FF beam. Half value layers (HVLs) and a dual parameter beam quality specifier (DPBQS) were determined. For the 6 MV FFFM beam, HVL and DPBQS values were very similar compared to those of the 6 MV FF beam, while for the 10 MV FFFM and FF beams, only %dd(10)x and HVL values were comparable (differences below 1.5%). This shows that matching the PDD at one depth does not guarantee other beam quality dependent parameters to be matched. For FFFU beams, all investigated beam quality specifiers were significantly different compared to those for FF beams of the same nominal accelerator potential. The DPBQS of the 6 MV FF and FFFM beams was equal within the measurement uncertainty and was comparable to published data of a machine with similar TPR20,10 and %dd(10)x. In contrast to that, the DPBQS's two parameters of the 10 MV FFFM beam were substantially higher compared to those for the 10 MV FF beam. PDD-matched FF and FFF beams of both nominal accelerator potentials were observed to have similar HVL values, indicating similarity of their primary dose components. Using the DPBQS revealed that the mean attenuation coefficient was found to be the same within the uncertainty of 0.8% for 6 MV FF and 6 MV FFFM beams, while for 10 MV

  15. Technical Note: On the impact of the incident electron beam energy on the primary dose component of flattening filter free photon beams

    International Nuclear Information System (INIS)

    Kuess, Peter; Georg, Dietmar; Lechner, Wolfgang; Palmans, Hugo

    2016-01-01

    Purpose: For commercially available linear accelerators (Linacs), the electron energies of flattening filter free (FFF) and flattened (FF) beams are either identical or the electron energy of the FFF beam is increased to match the percentage depth dose curve (PDD) of the FF beam (in reference geometry). This study focuses on the primary dose components of FFF beams for both kinds of settings, studied on the same Linac. Methods: The measurements were conducted on a VersaHD Linac (Elekta, Crawley, UK) for both FF and FFF beams with nominal energies of 6 and 10 MV. In the clinical setting of the VersaHD, the energy of FFF M (Matched) beams is set to match the PDDs of the FF beams. In contrast the incident electron beam of the FFF U beam was set to the same energy as for the FF beam. Half value layers (HVLs) and a dual parameter beam quality specifier (DPBQS) were determined. Results: For the 6 MV FFF M beam, HVL and DPBQS values were very similar compared to those of the 6 MV FF beam, while for the 10 MV FFF M and FF beams, only %dd(10) x and HVL values were comparable (differences below 1.5%). This shows that matching the PDD at one depth does not guarantee other beam quality dependent parameters to be matched. For FFF U beams, all investigated beam quality specifiers were significantly different compared to those for FF beams of the same nominal accelerator potential. The DPBQS of the 6 MV FF and FFF M beams was equal within the measurement uncertainty and was comparable to published data of a machine with similar TPR 20,10 and %dd(10) x . In contrast to that, the DPBQS’s two parameters of the 10 MV FFF M beam were substantially higher compared to those for the 10 MV FF beam. Conclusions: PDD-matched FF and FFF beams of both nominal accelerator potentials were observed to have similar HVL values, indicating similarity of their primary dose components. Using the DPBQS revealed that the mean attenuation coefficient was found to be the same within the uncertainty of

  16. Technical note: A new wedge-shaped ionization chamber component module for BEAMnrc to model the integral quality monitoring system®

    Science.gov (United States)

    Oderinde, Oluwaseyi Michael; du Plessis, FCP

    2017-12-01

    The purpose of this study was to develop a new component module (CM) namely IQM to accurately model the integral quality monitoring (IQM) system® to be used in the BEAMnrc Monte Carlo (MC) code. The IQM is essentially a double wedge ionization chamber with the central electrode plate bisecting the wedge. The IQM CM allows the user to characterize the double wedge of this ionization chamber and BEAMnrc can then accurately calculate the dose in this CM including its enclosed air regions. This has been verified against measured data. The newly created CM was added into the standard BEAMnrc CMs, and it will be made available through the NRCC website. The BEAMnrc graphical user interface (GUI) and particle ray-tracing techniques were used to validate the IQM geometry. In subsequent MC simulations, the dose scored in the IQM was verified against measured data over a range of square fields ranging from 1 × 1-30 × 30 cm2. The IQM system is designed for the present day need for a device that could verify beam output in real-time during treatment. This CM is authentic, and it can serve as a basis for researchers that have an interest in real-time beam delivery checking using wedge-shaped ionization chamber based instruments like the IQM.

  17. Enhancement of withstanding pressure of fibrin sealant by modified mixing ratio of fibrin sealant components for skull base reconstruction: technical note.

    Science.gov (United States)

    Saitoh, Youichi; Oshino, Satoru

    2013-01-01

    A method to enhance the withstanding pressure of fibrin sealant in gasket-seal closure to prevent cerebrospinal fluid (CSF) leakage after extended transsphenoidal surgery (ETSS) was investigated by adjusting the mixing ratio of the components. A plastic chamber (200 ml) was constructed with a lid made of hydroxyapatite with a hole 10 mm in diameter. The chamber could be pressurized via an opening in the side wall. The hole in the hydroxyapatite lid was covered with a Gore-Tex sheet, 15 mm in diameter. The margin of the sheet was free. Solutions A (fibrinogen 80 mg/ml) and B (thrombin 250 units/ml) of fibrin sealant were mixed in volume ratios of 1:1, 2:1, and 5:1, and applied to the Gore-Tex sheet, then water was introduced to cover the fibrin sealant. The pressure was measured at which air leakage occurred from the side of the Gore-Tex sheet. The pressure values for A/B ratios of 1:1, 2:1, and 5:1 were 117 ± 23.8 mmH(2)O (mean ± standard error) (n = 5), 234 ± 38.8 mmH(2)O (n = 5), and 345 ± 36.4 mmH(2)O (n = 5), respectively, in the acute phase (5 minutes after application of fibrin sealant). Pressures were increased after 24 hours, and that for 5:1 was the highest (373 ± 40.4 mmH(2)O, n = 5). The use of devices such as syringes specially designed to mix solutions A and B in the ratio of 5:1 can easily enhance the preventive effect of fibrin sealant against CSF leakage in ETSS.

  18. Non-technical skills in histopathology: definition and discussion.

    Science.gov (United States)

    Johnston, Peter W; Fioratou, Evie; Flin, Rhona

    2011-09-01

    Health care is a high-risk industry, with most documented adverse incidents being associated with 'human factors' including cognitive and social skills termed 'non-technical skills'. Non-technical skills complement the diagnostic and specialist skills and professional attributes required by medical practitioners, including histopathologists, and can enhance the quality of practice and delivery of health-care services and thus contribute to patient safety. This review aims to introduce histopathologists to non-technical skills and how these pertain to everyday histopathological practice. Drawing from other domains in medicine, specifically anaesthesia and surgery, a variety of non-technical skills are identified and described in the context of histopathology to illustrate the role each plays, often collectively, in daily practice. The generic non-technical skills are defined as situation awareness, decision-making, communication, teamwork, leadership, managing stress and coping with fatigue. Example scenarios from histopathology are presented and the contributions to outcomes made by non-technical skills are explained. Consideration of these specific non-technical skills as a component in histopathology training may benefit practitioners as well as assuring patient safety. © 2011 Blackwell Publishing Limited.

  19. Subduction initiation and recycling of Alboran domain derived crustal components prior to the intra-crustal emplacement of mantle peridotites in the Westernmost Mediterranean: isotopic evidence from the Ronda peridotite

    Science.gov (United States)

    Varas-Reus, María Isabel; Garrido, Carlos J.; Bosch, Delphine; Marchesi, Claudio Claudio; Acosta-Vigil, Antonio; Hidas, Károly; Barich, Amel

    2014-05-01

    During Late Oligocene-Early Miocene different domains formed in the region between Iberia and Africa in the westernmost Mediterranean, including thinned continental crust and a Flysch Trough turbiditic deposits likely floored by oceanic crust [1]. At this time, the Ronda peridotite likely constituted the subcontinental lithospheric mantle of the Alboran domain, which mantle lithosphere was undergoing strong thinning and melting [2] [3] coevally with Early Miocene extension in the overlying Alpujárride-Maláguide stacked crust [4, 5]. Intrusive Cr- rich pyroxenites in the Ronda massif records the geochemical processes occurring in the subcontinental mantle of the Alboran domain during the Late Oligocene [6]. Recent isotopic studies of these pyroxenites indicate that their mantle source was contaminated by a subduction component released by detrital crustal sediments [6]. This new data is consistent with a subduction setting for the late evolution of the Alboran lithospheric mantle just prior to its final intracrustal emplacement in the early Miocene Further detailed structural studies of the Ronda plagioclase peridotites-related to the initial stages of ductile emplacement of the peridotite-have led to Hidas et al. [7] to propose a geodynamic model where folding and shearing of an attenuated mantle lithosphere occurred by backarc basin inversion followed by failed subduction initiation that ended into the intracrustal emplacement of peridotite into the Alboran wedge in the earliest Miocene. This hypothesis implies that the crustal component recorded in late, Cr-rich websterite dykes might come from underthrusted crustal rocks from the Flysch and/or Alpujárrides units that might have been involved in the earliest stages of this subduction initiation stage. To investigate the origin of crustal component in the mantle source of this late magmatic event recorded by Cr-pyroxenites, we have carried out a detail Sr-Nd-Pb-Hf isotopic study of a variety of Betic

  20. The domain-specific and domain-general relationships of visuospatial working memory to reasoning ability.

    Science.gov (United States)

    Shipstead, Zach; Yonehiro, Jade

    2016-10-01

    The degree to which visuospatial working memory (VSWM) is separable from working memory in general is an open question. On one hand, the construct is often researched as a unitary, domain-specific system. On the other, there is evidence that VWSM shares a common processing component with verbal memory. One might interpret this shared component as domain-general attention. We used confirmatory factor analysis to demonstrate that VSWM shares a domain-general component with verbal memory tasks and has a domain-specific component that is independent of verbal memory. Furthermore, the domain-general component was found to correlate with reasoning ability in both the visuospatial and verbal domains. The domain-specific component only correlated with reasoning ability when the tests had a strong visuospatial component. We argue that theories of VSWM need to place greater emphasis on its multiply determined nature.

  1. Evolution of Web-Based Applications Using Domain-Specific Markup Languages

    Directory of Open Access Journals (Sweden)

    Guntram Graef

    2000-11-01

    Full Text Available The lifecycle of Web-based applications is characterized by frequent changes to content, user interface, and functionality. Updating content, improving the services provided to users, drives further development of a Web-based application. The major goal for the success of a Web-based application becomes therefore its evolution. Though, development and maintenance of Web-based applications suffers from the underlying document-based implementation model. A disciplined evolution of Web based applications requires the application of software engineering practice for systematic further development and reuse of software artifacts. In this contribution we suggest to adopt the component paradigm to development and evolution of Web-based applications. The approach is based on a dedicated component technology and component-software architecture. It allows abstracting from many technical aspects related to the Web as an application platform by introducing domain specific markup languages. These languages allow the description of services, which represent domain components in our Web-component-software approach. Domain experts with limited knowledge of technical details can therefore describe application functionality and the evolution of orthogonal aspects of the application can be de-coupled. The whole approach is based on XML to achieve the necessary standardization and economic efficiency for the use in real world projects.

  2. Domain crossing

    DEFF Research Database (Denmark)

    Schraefel, M. C.; Rouncefield, Mark; Kellogg, Wendy

    2012-01-01

    In CSCW, how much do we need to know about another domain/culture before we observe, intersect and intervene with designs. What optimally would that other culture need to know about us? Is this a “how long is a piece of string” question, or an inquiry where we can consider a variety of contexts a...

  3. Methodology for technical risk assessment

    International Nuclear Information System (INIS)

    Waganer, L.M.; Zuckerman, D.S.

    1983-01-01

    A methodology has been developed for and applied to the assessment of the technical risks associated with an evolving technology. This methodology, originally developed for fusion by K. W. Billman and F. R. Scott at EPRI, has been applied to assess the technical risk of a fuel system for a fusion reactor. Technical risk is defined as the risk that a particular technology or component which is currently under development will not achieve a set of required technical specifications (i.e. probability of failure). The individual steps in the technical risk assessment are summarized. The first step in this methodology is to clearly and completely quantify the technical requirements for the particular system being examined. The next step is to identify and define subsystems and various options which appear capable of achieving the required technical performance. The subsystem options are then characterized regarding subsystem functions, interface requirements with the subsystems and systems, important components, developmental obstacles and technical limitations. Key technical subsystem performance parameters are identified which directly or indirectly relate to the system technical specifications. Past, existing and future technical performance data from subsystem experts are obtained by using a Bayesian Interrogation technique. The input data is solicited in the form of probability functions. Thus the output performance of the system is expressed as probability functions

  4. Applying technical versatility

    Energy Technology Data Exchange (ETDEWEB)

    None

    1970-01-01

    The breadth and depth of the diversified technical programs at Mound Laboratory since its inception are characterized by a record of competence and versatility during the past generation. A spectrum of mission assignments has been completed successfully in such diverse technical areas as process development and manufacturing of explosive components, research on fuels for the Civilian Power Reactor Program, separation of radioactive materials, fabrication of radioisotopic heat sources, stable gaseous isotope separation and purification, and many other areas. Mound Laboratory is one of the key U.S. Atomic Energy Commission sites that has demonstrated its technical competence in both weapons and non-weapons activities. This report has been prepared to complement the AEC’s vigorous program of scientific information dissemination. Three broad areas of technical competence are highlighted here: explosive technology, radionuclide technology, and stable gaseous isotope separation, which encompass a broad variety of techniques and supporting disciplines.

  5. Imagining Technicities

    DEFF Research Database (Denmark)

    Liboriussen, Bjarke; Plesner, Ursula

    2011-01-01

    to the elements of taste and skill. In the final analysis those references were synthesized as five imagined technicities: the architect, the engineer, the client, the Chinese, and the Virtual World native. Because technicities are often assumed and rarely discussed as actants who influence practice, their role......, this article focuses on innovative uses of virtual worlds in architecture. We interviewed architects, industrial designers and other practitioners. Conceptually supported by an understanding of technicity found in Cultural Studies, the interviews were then coded with a focus on interviewees’ references...... in cooperation and development of ICTs seems to pass unnoticed. However, since they are aligned into ICTs, technicities impact innovation....

  6. Review of technical specifications

    International Nuclear Information System (INIS)

    Bedrich, M.; Scholz, D.

    1980-01-01

    The present paper deals with position and function of technical specifications before and during the manufacturing of reactor components, their structure and reasons for specific regulations due to safety philosophy and explains the cooperation of supplier, manufacturer, utilities and supervisory organizations. (RW)

  7. Trusted Domain

    DEFF Research Database (Denmark)

    Hjorth, Theis Solberg; Torbensen, Rune

    2012-01-01

    In the digital age of home automation and with the proliferation of mobile Internet access, the intelligent home and its devices should be accessible at any time from anywhere. There are many challenges such as security, privacy, ease of configuration, incompatible legacy devices, a wealth...... of wireless standards, limited resources of embedded systems, etc. Taking these challenges into account, we present a Trusted Domain home automation platform, which dynamically and securely connects heterogeneous networks of Short-Range Wireless devices via simple non-expert user. interactions, and allows...... remote access via IP-based devices such as smartphones. The Trusted Domain platform fits existing legacy technologies by managing their interoperability and access controls, and it seeks to avoid the security issues of relying on third-party servers outside the home. It is a distributed system...

  8. Magnetic Domains

    OpenAIRE

    Harland, Derek; Palmer, Sam; Saemann, Christian

    2012-01-01

    Recently a Nahm transform has been discovered for magnetic bags, which are conjectured to arise in the large n limit of magnetic monopoles with charge n. We interpret these ideas using string theory and present some partial proofs of this conjecture. We then extend the notion of bags and their Nahm transform to higher gauge theories and arbitrary domains. Bags in four dimensions conjecturally describe the large n limit of n self-dual strings. We show that the corresponding Basu-Harvey equatio...

  9. Technical Network

    CERN Multimedia

    2007-01-01

    In order to optimize the management of the Technical Network (TN), to ease the understanding and purpose of devices connected to the TN, and to improve security incident handling, the Technical Network Administrators and the CNIC WG have asked IT/CS to verify the "description" and "tag" fields of devices connected to the TN. Therefore, persons responsible for systems connected to the TN will receive email notifications from IT/CS asking them to add the corresponding information in the network database. Thank you very much for your cooperation. The Technical Network Administrators & the CNIC WG

  10. Technical Network

    CERN Multimedia

    2007-01-01

    In order to optimise the management of the Technical Network (TN), to facilitate understanding of the purpose of devices connected to the TN and to improve security incident handling, the Technical Network Administrators and the CNIC WG have asked IT/CS to verify the "description" and "tag" fields of devices connected to the TN. Therefore, persons responsible for systems connected to the TN will receive e-mails from IT/CS asking them to add the corresponding information in the network database at "network-cern-ch". Thank you very much for your cooperation. The Technical Network Administrators & the CNIC WG

  11. Cross Domain Analogies for Learning Domain Theories

    National Research Council Canada - National Science Library

    Klenk, Matthew; Forbus, Ken

    2007-01-01

    .... This work describes a method for learning new domain theories by analogy. We use analogies between pairs of problems and worked solutions to create a domain mapping between a familiar and a new domain...

  12. Socio-technical security metrics

    NARCIS (Netherlands)

    Gollmann, D.; Herley, C.; Koenig, V.; Pieters, W.; Sasse, M.A.

    2015-01-01

    Report from Dagstuhl seminar 14491. This report documents the program and the outcomes of Dagstuhl Seminar 14491 “Socio-Technical Security Metrics”. In the domain of safety, metrics inform many decisions, from the height of new dikes to the design of nuclear plants. We can state, for example, that

  13. Bifurcations of Baker domains

    Science.gov (United States)

    Lauber, Arnd

    2007-07-01

    We consider the family of transcendental entire functions given by \\{f_c:{\\mathbb C} \\rightarrow {\\mathbb C}:z-c+e^z, c \\in {\\mathbb C} \\} . If Re c > 0, then fc features a Baker domain as the only component of the Fatou set, while the functions fc show a different dynamical behaviour if c \\in \\rmi{\\mathbb R} . We describe the dynamical planes of these functions and show that the Julia sets converge in the limit process f_{c_1+\\rmi c_2} \\rightarrow f_{\\rmi c_2} with respect to the Hausdorff metric, where c_1 \\in {\\mathbb R}^+ and c_2 \\in {\\mathbb R} . We use this to show that Baker domains of any type (concerning a classification of König) are not necessarily stable under perturbation.

  14. Don’t Forget the Cyber! Why the Joint Force Commander Must Integrate Cyber Operations Across Other War Fighting Domains, and How a Joint Forces Cyberspace Component Commander Will Help

    Science.gov (United States)

    2009-05-04

    expanding his color palette . This recommendation follows DoD‟s declaration that cyberspace is a global domain, analogous to land, sea, air and space...Any specialist (i.e. UAV Pilot, Power Plant Engineer, Banker, Intelligence Officer, etc) uses the freedom of access that is achieved and maintained

  15. Tryptophan phosphorescence spectroscopy reveals that a domain in the NAD(H)-binding component (dI) of transhydrogenase from Rhodospirillum rubrum has an extremely rigid and conformationally homogeneous protein core

    NARCIS (Netherlands)

    Broos, J; Gabellieri, E; van Boxel, GI; Jackson, JB; Strambini, GB; Strambini, Giovanni B.

    2003-01-01

    The characteristics of tryptophan phosphorescence from the NAD(H)-binding component (dI) component of Rhodospirillum rubrum transhydrogenase are described. This enzyme couples hydride transfer between NAD( H) and NADP( H) to proton translocation across a membrane and is only active as a dimer.

  16. .Gov Domains API

    Data.gov (United States)

    General Services Administration — This dataset offers the list of all .gov domains, including state, local, and tribal .gov domains. It does not include .mil domains, or other federal domains outside...

  17. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    2010-01-01

    Operational Experience At the end of the first full-year running period of LHC, CMS is established as a reliable, robust and mature experiment. In particular common systems and infrastructure faults accounted for <0.6 % CMS downtime during LHC pp physics. Technical operation throughout the entire year was rather smooth, the main faults requiring UXC access being sub-detector power systems and rack-cooling turbines. All such problems were corrected during scheduled technical stops, in the shadow of tunnel access needed by the LHC, or in negotiated accesses or access extensions. Nevertheless, the number of necessary accesses to the UXC averaged more than one per week and the technical stops were inevitably packed with work packages, typically 30 being executed within a few days, placing a high load on the coordination and area management teams. It is an appropriate moment for CMS Technical Coordination to thank all those in many CERN departments and in the Collaboration, who were involved in CMS techni...

  18. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    2010-01-01

    Operational Experience Since the closure of the detector in February, the technical operation of CMS has been quite smooth and reliable. Some minor interventions in UXC were required to cure failures of power supplies, fans, readout boards and rack cooling connections, but all these failures were repaired in scheduled technical stops or parasitically during access dedicated to fixing LHC technical problems. The only occasion when CMS had to request an access between fills was to search for the source of an alarm from the leak-detection cables mounted in the DT racks. After a few minutes of diagnostic search, a leaking air-purge was found. Replacement was complete within 2 hours. This incident demonstrated once more the value of these leak detection cables; the system will be further extended (during the end of year technical stop) to cover more racks in UXC and the floor beneath the detector. The magnet has also been operating reliably and reacted correctly to the 14s power cut on 29 May (see below). In or...

  19. Technical endoscopy

    International Nuclear Information System (INIS)

    Cavalar, K.O.

    1988-01-01

    A survey is provided on different versions of endoscopes, taking into account the new developments of video endoscopy. With a variety of practical examples it is shown that technical tests using endoscopy are a demanding task for nondestructive testing, whose requirements can only be met on a customized basis. (orig./HP) [de

  20. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch Monday 9 February 2004 From 10:00 to 12:00 - IT Auditorium - bldg. 31, 3rd floor ANSOFT High-Frequency Seminar David Prestaux, Application Engineer, ANSOFT F-78535 BUC, France This Technical Training seminar will present two Ansoft application products: Ansoft HFSS and Ansoft Designer. Ansoft HFSS makes use of the Finite Element Method (FEM) to calculate field solutions from first principles. It can accurately predict all high-frequency behaviours such as dispersion, mode conversion, and losses due to materials and radiation. Ansoft Designer is a suite of design tools to fully integrate high-frequency, physics-based electromagnetic simulations into a seamless system-level simulation environment. Ansoft Designer uses a simple interface to give complete control over every design task, by a method allowing multiple solvers, Solver on Demand. • Introduction • Overview of the Ansoft Total solution • Ansoft HFSS 9...

  1. Transform domain steganography with blind source separation

    Science.gov (United States)

    Jouny, Ismail

    2015-05-01

    This paper applies blind source separation or independent component analysis for images that may contain mixtures of text, audio, or other images for steganography purposes. The paper focuses on separating mixtures in the transform domain such as Fourier domain or the Wavelet domain. The study addresses the effectiveness of steganography when using linear mixtures of multimedia components and the ability of standard blind sources separation techniques to discern hidden multimedia messages. Mixing in the space, frequency, and wavelet (scale) domains is compared. Effectiveness is measured using mean square error rate between original and recovered images.

  2. Impedance of accelerator components

    International Nuclear Information System (INIS)

    Corlett, J.N.

    1996-05-01

    As demands for high luminosity and low emittance particle beams increase, an understanding of the electromagnetic interaction of these beams with their vacuum chamber environment becomes more important in order to maintain the quality of the beam. This interaction is described in terms of the wake field in time domain, and the beam impedance in frequency domain. These concepts are introduced, and related quantities such as the loss factor are presented. The broadband Q = 1 resonator impedance model is discussed. Perturbation and coaxial wire methods of measurement of real components are reviewed

  3. affective domain in developing environmental

    African Journals Online (AJOL)

    AN ETHIC FOR GEOGRAPHY: THE ROLE OF THE. AFFECTIVE DOMAIN IN DEVELOPING ENVIRONMENTAL. AWARENESS. Margaret E. Marker. Geography is a subject with integral ethical and moral components. However, because of the subject's traditionally close association with scientific rationality this factor has not ...

  4. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2011-01-01

    In this report we will review the main achievements of the Technical Stop and the progress of several centrally-managed projects to support CMS operation and maintenance and prepare the way for upgrades. Overview of the extended Technical Stop  The principal objectives of the extended Technical Stop affecting the detector itself were the installation of the TOTEM T1 telescopes on both ends, the readjustment of the alignment link-disk in YE-2, the replacement of the light-guide sleeves for all PMs of both HFs, and some repairs on TOTEM T2 and CASTOR. The most significant tasks were, however, concentrated on the supporting infrastructure. A detailed line-by-line leak search was performed in the C6F14 cooling system of the Tracker, followed by the installation of variable-frequency drives on the pump motors of the SS1 and SS2 tracker cooling plants to reduce pressure transients during start-up. In the electrical system, larger harmonic filters were installed in ...

  5. 75 FR 29732 - Career and Technical Education Program-Promoting Rigorous Career and Technical Education Programs...

    Science.gov (United States)

    2010-05-27

    ... DEPARTMENT OF EDUCATION Career and Technical Education Program--Promoting Rigorous Career and Technical Education Programs of Study Catalog of Federal Domestic Assistance (CFDA) Number: 84.051C. AGENCY... technical education programs of study (POSs) through the use of ten key components based on the ``Program of...

  6. Modeling software systems by domains

    Science.gov (United States)

    Dippolito, Richard; Lee, Kenneth

    1992-01-01

    The Software Architectures Engineering (SAE) Project at the Software Engineering Institute (SEI) has developed engineering modeling techniques that both reduce the complexity of software for domain-specific computer systems and result in systems that are easier to build and maintain. These techniques allow maximum freedom for system developers to apply their domain expertise to software. We have applied these techniques to several types of applications, including training simulators operating in real time, engineering simulators operating in non-real time, and real-time embedded computer systems. Our modeling techniques result in software that mirrors both the complexity of the application and the domain knowledge requirements. We submit that the proper measure of software complexity reflects neither the number of software component units nor the code count, but the locus of and amount of domain knowledge. As a result of using these techniques, domain knowledge is isolated by fields of engineering expertise and removed from the concern of the software engineer. In this paper, we will describe kinds of domain expertise, describe engineering by domains, and provide relevant examples of software developed for simulator applications using the techniques.

  7. Other components

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    This chapter includes descriptions of electronic and mechanical components which do not merit a chapter to themselves. Other hardware requires mention because of particularly high tolerance or intolerance of exposure to radiation. A more systematic analysis of radiation responses of structures which are definable by material was given in section 3.8. The components discussed here are field effect transistors, transducers, temperature sensors, magnetic components, superconductors, mechanical sensors, and miscellaneous electronic components

  8. INDOT Technical Training Plan : [Technical Summary

    Science.gov (United States)

    2012-01-01

    A wide range of job classifications, increasing technical : performance expectations, licensing and certification requirements, : budget restrictions and frequent department : reorganization has made technical training of employees : more difficult, ...

  9. Meta-Domains for Automated Model Building

    National Research Council Canada - National Science Library

    Easley, Matthew; Bradley, Elizabeth

    1999-01-01

    .... In particular, we introduce a new structure for automated model building known as a meta-domain which, when instantiated with components, tailors the space of candidate models to the system at hand...

  10. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2013-01-01

    For the reporting period, the CMS common systems and infrastructure worked well, without failures that caused significant data losses. One more disconnection of the magnet cold box occurred in the shadow of interruptions in data taking, caused by a series of technical faults. The recognition during 2012 that re-connection can only safely be done at around 2 T implies a minimum magnet recovery time of 12 hours and raises serious concerns about the number of ramping cycles of the magnet these incidents cause. This has triggered studies of how to make the cryo-system of the magnet more robust against failures. The proton-proton run ended just before the end-of-year CERN closure, during which CASTOR was installed on the negative end of CMS and both ZDC calorimeters were installed in TAN absorbers the LHC tunnel, in preparation for the heavy-ion run. The installation of CASTOR was an excellent “engineering test” of procedures for working in an activated environment. Despite some technical pr...

  11. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2011-01-01

      Operational experience 2011 CMS is approaching the end of a very successful year of operation. Proton- proton running ended in the late afternoon of 30th October with a stunning 5.73 fb–1 delivered by LHC, of which CMS recorded 5.22 fb–1. During heavy-ion operation, which continues until 7th December, both the accelerator and the CMS detector have also performed very well. Despite the encouraging overall reliability of technical operation, several infrastructure failures which occurred since the last Bulletin are worthy of mention, with one leading for the first time to significant data-loss. On 10th July, a CERN-wide power failure brought down essentially all services including the magnet, due to an MCS setting being left in “manual” after the recent technical stop, but there was no significant damage and the detector was operational before the LHC, despite a slow and tortuous recovery (one of several indications this year that there is room for improve...

  12. TECHNICAL COORDINATION

    CERN Multimedia

    Austin Ball

    Summary of progress since last CMS week. Ten years of construction work have been completed. CMS is closed, in very close to the ideal low luminosity configuration, and performed well in the first tests with LHC beam. Behind this encouraging news is the story of a summer of intense commitment by many teams (from the collaboration and 3 CERN departments) working together, against the clock and despite many minor setbacks, to ensure that the experiment was ready to play a leading role in the excitement of September 10. Following beampipe bakeout and refill with pure neon, a magnificent effort by the ECAL group and the pt 5 technical crew made it possible to install and commission all 4 ECAL endcap Dees before the end of August. In the shadow of this activity, the barrel and forward pixel trackers and part of the beam monitoring were installed within the vac tank. The pt 5 technical teams then succeeded in safely removing the 20t installation tables and their support blocks from beneath the already installed ...

  13. Center for Technology for Advanced Scientific Component Software (TASCS)

    Energy Technology Data Exchange (ETDEWEB)

    Damevski, Kostadin [Virginia State Univ., Petersburg, VA (United States)

    2009-03-30

    A resounding success of the Scientific Discover through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedened computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS) tackles these issues by exploiting component-based software development to facilitate collaborative hig-performance scientific computing.

  14. The different roles of aggrecan interaction domains

    DEFF Research Database (Denmark)

    Aspberg, Anders

    2012-01-01

    glycosaminoglycan chains, that provide the basis for the viscoelastic properties necessary for load distribution over the articular surface. This review is focused on the globular domains of aggrecan and their role in anchoring the proteoglycans to other extracellular matrix components. The N-terminal G1 domain...

  15. Electronic components

    CERN Document Server

    Colwell, Morris A

    1976-01-01

    Electronic Components provides a basic grounding in the practical aspects of using and selecting electronics components. The book describes the basic requirements needed to start practical work on electronic equipment, resistors and potentiometers, capacitance, and inductors and transformers. The text discusses semiconductor devices such as diodes, thyristors and triacs, transistors and heat sinks, logic and linear integrated circuits (I.C.s) and electromechanical devices. Common abbreviations applied to components are provided. Constructors and electronics engineers will find the book useful

  16. Component testing

    International Nuclear Information System (INIS)

    Hutchings, M.T.; Schofield, Peter; Seymour, W.A.J.

    1986-01-01

    A method for non-destructive testing of an industrial component to ascertain if it is a single crystal, and to find the crystal orientations of those parts of the component which are single crystals, involves irradiating the component with a monochromatic collimated neutron beam. Diffracted neutron beams are observed live by means of LiF/ZnS composite screen, an image intensifier and a television camera and screen. (author)

  17. Technical risks as a constitutional problem

    International Nuclear Information System (INIS)

    Murswiek, D.

    1991-01-01

    Between the constitutional duty to protect, and the limits of protecting powers lies a domain where governmental bodies are empowered, but not obligated, to control and plan technical development and risks. Thus there is political responsibility for the way technical matters are handled, and a constitutional perspetive for accepting technical risks. As long as there has been general consent for technical progress, politicians were able to let the progress process take its course. Now they are asked to intervene. The transformation of living conditions through technical innovation has a greater significance for the individual and the State as a whole than most of the other matters of political decision-making. It would be irresponsible therefore to leave technical development to its own dynamics, and not continuously assess impacts of new technologies, weight up possible advantages and disadvantages, and change the course if necessary. (orig./HWCH) [de

  18. Technical knowledge creation

    DEFF Research Database (Denmark)

    Søberg, Peder Veng

    2017-01-01

    Purpose - The purpose of the paper is to amend shortcomings of existing theory concerning organizational learning and knowledge management. Design/methodology/approach – The paper reviews and refines existing theory. Findings - Findings from cognitive neuroscience suggest that technical knowledge...... domains essential for product development are largely nonlinguistic. Operations management/strategy tools enable the use of tacit knowledge in its tacit form and discourage premature standardization. Similarly, language use introduces standardization, which if introduced prematurely, causes incrementalism...... in line with findings from product development research. However, frameworks on organizational learning and knowledge management focus on language development and neglect use of tacit knowledge and the benefits involved with allowing elements of new product ideas to mature in a tacit form. Originality...

  19. Technical presentation

    CERN Multimedia

    FP Department

    2009-01-01

    07 April 2009 Technical presentation by Leuze Electronics: 14.00 – 15.00, Main Building, Room 61-1-017 (Room A) Photoelectric sensors, data identification and transmission systems, image processing systems. We at Leuze Electronics are "the sensor people": we have been specialising in optoelectronic sensors and safety technology for accident prevention for over 40 years. Our dedicated staff are all highly customer oriented. Customers of Leuze Electronics can always rely on one thing – on us! •\tFounded in 1963 •\t740 employees •\t115 MEUR turnover •\t20 subsidiaries •\t3 production facilities in southern Germany Product groups: •\tPhotoelectric sensors •\tIdentification and measurements •\tSafety devices

  20. Technical presentation

    CERN Multimedia

    GS Department

    2010-01-01

    10 March 2010 DYNEOS 10:00 – 12:00 - Main Building, Room B, 61-1-009 Dyneos AG is active in the fields of photonics, laser and high-precision positioning. Our highly qualified engineer team has more than 30 years of experience in electro-optical solutions sales. The engineers are supported by a technical and administrative team. We are focused on the Swiss market and represent six suppliers (Coherent, PI Physik Instrumente, SIOS, Nanonics Imaging, APE, Ekspla) in order to give a qualified sales and service support to our customers. Our products are dedicated to the research field as well as to industry. In addition to standard catalog products, we offer custom designs to fulfill the specific needs of OEM customers or specific applications.

  1. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2010-01-01

    Overview Once again, the bulk of this article reviews the intense activity of a recently completed shutdown, which, although quite unforeseeable until a few weeks before it started, proved by its success that our often advertised capability to conduct major maintenance within a two month period is real. Although safely completed, on-time to remarkable precision, the activity was not without incident, and highlighted our dependence on many experienced, specialist teams and their precise choreography. Even after the yoke was safely closed, magnet re-commissioning and beampipe pumpdown showed new and thought-provoking behaviour. The struggle to maintain adequate technical resources will be a pre-occupation over the coming months, in parallel with the start of truly sustained operation, for which various procedures are still being put in place. Planning for future shutdowns must now become a high priority, with many working groups and task forces already in existence to prepare infrastructure improvements and to...

  2. Marketing information: The technical report as product

    Science.gov (United States)

    Stoher, F. F.; Pinelli, T. E.

    1981-01-01

    Technical reports constitute a product, the primary means for communicating the results of research to the user. The Langley scientific and technical information (STI) review and evaluation project undertook a review of the technical report as an effective product for information communication. Style manuals describing theory and practice in technical report preparation; publication manuals covering such factors as design, layout, and type style; and copies of technical reports were obtained from industrial, academic, governmental, and research organizations. Based on an analysis of this material, criteria will be established for the report components, for the relationship of the components within the report context, and for the overall report organization. The criteria will be used as bench marks and compared with the publication standards currently used to prepare NASA technical reports.

  3. Technical Training: Technical Training Seminar

    CERN Multimedia

    2004-01-01

    TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch Tuesday 3 February 2004 From 09:00 to 13:30 - Training Centre Auditorium - bldg. 593, room 11 USB (Universal Serial Bus) CYPRESS Seminar Claudia Colombini, Field Application Engineer CYPRESS ActiveComp Electronic GmbH D-85077 MANCHING, Germany As a pioneer in USB, CYPRESS sets the standard for cost-effective solutions without sacrificing functionality, performance or reliability. Having shipped over 200 million USB devices, Cypress is the undisputed market leader and demonstrates unmatched USB expertise. With the industry's broadest selection of USB solutions, Cypress has the right silicon, software and support for every USB application, from Low-speed to High-Speed and USB On-The-Go (OTG). 9:00 - 10:30 Overview of USB systems. USB CYPRESS product overview. Peripherals: Low Speed, Full Speed, High Speed (1.1 and 2.0). Hub Solutions, Embedded Host Solutions, On-The-Go (OTG) and wireless USB. USB Development Tools (first part) 10:30 -...

  4. FLAMMABLE GAS TECHNICAL BASIS DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    KRIPPS, L.J.

    2005-03-03

    This document describes the qualitative evaluation of frequency and consequences for DST and SST representative flammable gas accidents and associated hazardous conditions without controls. The evaluation indicated that safety-significant structures, systems and components (SSCs) and/or technical safety requirements (TSRs) were required to prevent or mitigate flammable gas accidents. Discussion on the resulting control decisions is included. This technical basis document was developed to support WP-13033, Tank Farms Documented Safety Analysis (DSA), and describes the risk binning process for the flammable gas representative accidents and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous condition based on an evaluation of the event frequency and consequence.

  5. Domain wall diffusion and domain wall softening

    International Nuclear Information System (INIS)

    Lee, W T; Salje, E K H; Bismayer, U

    2003-01-01

    A number of experimental and computational studies of materials have shown that transport rates in domain walls may significantly differ from those in the bulk. One possible explanation for enhanced transport in a domain wall is that the domain wall is elastically soft with respect to the bulk. We investigate the softening of a ferroelastic domain wall in a simple, generic model. We calculate saddle point energies of solute atoms in the bulk and domain wall, using a geometry such that variation in the saddle point energy cannot be attributed to the structural differences of the bulk and the wall, but must instead be attributed to softening of the wall. Our results show a reduction of the saddle point energy in the wall, thus indicating that, in this model at least, domain walls are elastically soft compared with the bulk. A simple analysis based on an Einstein model allows us to explain the observed softening of the wall

  6. Trade name and trademark versus domain

    Directory of Open Access Journals (Sweden)

    Jarmila Pokorná

    2013-01-01

    Full Text Available Internet domains have become an integral part of our lives, so one can easily understand that during their use, conflicts can arise, whose participants will search for rules enabling resolution of conflicts. Since the domain name is a replacement of the computer IP address, in the technical sense of the word, this does not concern for domain names a commercial name or brand, because it primarily does not belong to a person in the legal sense of the word and does not serve for its individualization. The average user regularly affiliates domain names with a person offering goods or services on the relevant Website. Domain names used by entrepreneurs in their business activity are often chosen so that the second-level domain (SLD would use words that form the trade name of corporations formed of trading companies. This fact brings domain names close to such designations that serve the individualization of persons or products, especially the trademarks and the commercial name. Domains can come into conflict with the rights to designations, especially trademarks and commercial names. Court practice is resolving these conflicts using rules for unfair competition, or rules for protection of commercial names and trademarks, but it is not ruled out that in the future, special legal regulation of domain names could be established.

  7. Research Needs: Career and Technical Education

    Science.gov (United States)

    Kosloski, Michael F., Jr.; Ritz, John M.

    2016-01-01

    Research is an important component of each professional field. This study sought to determine topics that needed further research in the school subjects known as career and technical education. It determined topics that needed to be researched related to high school career and technical education (CTE) and the preparation for teaching CTE in…

  8. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball and W. Zeuner

    2012-01-01

      UXC + detectors As explained in detail in the November 2011 bulletin, the bellows unit at −18.5 m from the CMS interaction point was identified as a prime candidate for the regularly occurring pressure spikes which occasionally led to sustained severe background conditions in 2011, affecting dead time and data quality. Similar regions in LHC with vacuum instabilities were observed to be close to bellows, which radiography showed to have distorted RF-fingers — on removal, they proved to have been severely overheated. The plans for the Year-End Technical Stop were adapted to prioritise radiography of the bellows at 16 m to 18 m either end of CMS. Excellent work by the beam pipe, survey and heavy mechanical teams allowed the X-rays to be taken as planned on 20th December, showing that the bellow at −18.5m had an obvious non-conformity. The RF-fingers were found inside the end of the opposing flared pipe instead of outside. In addition, the overlap between fingers and...

  9. TECHNICAL COORDINATION

    CERN Multimedia

    Austin Ball

    2013-01-01

      Since the last report, much visible progress has been made, as the LS1 programme approaches the halfway point. From early October, technical and safety shift-crew have been present around the clock, allowing detectors to stay switched on overnight, ensuring that safety systems are operational and instructions for non-expert shift-crew are clear. LS1 progress Throughout the summer, whilst the solenoid vacuum tank and YB0 surfaces were accessible, an extensive installation programme took place to prepare for Tracker colder operation and the PLT installation, in 2014, the Phase 1 Pixel Tracker installation, in 2016–’17, and the HCAL Phase 1 upgrade completion, ending in LS2. This included pipework for N2 or dry air to flush the Tracker bulkhead region, many sensors to monitor temperature and dew point in the Tracker and its service channels, heating wires outside the Tracker cooling bundles, supports for the new vacuum-jacketed, concentric, CO2 Pixel cooling lines, the PLT cool...

  10. Technical innovation and management

    International Nuclear Information System (INIS)

    Yoon, Yang Cheol

    1982-08-01

    This book gives explanations of the conception of technical innovation, development plan in Korea, connection between technology and a growth factor in national income, problem of technical innovation in developing country, analysis on cooperation between a developed country and a developing country, evaluation and strategy of technical development in Korea, technical innovation of industry, management of technical industry, analysis of special condition in Korea.

  11. A global reference model of the domain name system

    NARCIS (Netherlands)

    Koc, Y.; Jamakovic, A.; Gijsen, B.M.M.

    2012-01-01

    The domain name system (DNS) is a crucial component of the Internet. At this time, the DNS is facing major changes such as the introduction of DNSSEC and Internationalized Domain Name extensions (IDNs), the adoption of IPv6 and the upcoming extension of new generic top-level domains. These changes

  12. TECHNICAL COORDINATION

    CERN Multimedia

    Austin Ball

    The 2008-9 CMS shutdown has reached its final phase. The yoke is closed again and the HFs are being prepared for lifting to beam height. Assuming no last minute problems occur, the detector will be ready for magnetic field tests by the end of June. The commitment of all the teams involved has ensured that an ambitious programme of work, including several tasks unforeseen in November 08, is nevertheless concluding on-time and successfully. All efforts are now being made to be ready for the CRAFT09 exercise. The way to proceed after CRAFT will depend on the LHC re-start schedule (to be clarified around the end of June). Options will be discussed during this CMS week. Shutdown 2008-9 Sub-Detectors As a reminder, the major shutdown activities on the detector components are listed below; details on each point can be found elsewhere in this bulletin. •    Installation and check-out of the Preshower detector on both endcaps •    Mainten...

  13. Social risk assessment of large technical systems

    NARCIS (Netherlands)

    Pasman, H.J.; Vrijling, J.K.

    2003-01-01

    A probabilistic approach to engineering advances. Since risk adhering to a technical structure can be determined quantitatively easier and more accurately than before, criteria for decision making are becoming more important. If the structure is in the public domain, and benefits are not felt, the

  14. An appraisal of undergraduate curriculum of technical education in ...

    African Journals Online (AJOL)

    The purpose of this study was to appraise the curriculum of technical teacher education in terms of its compatibility to the goals of the programme. A sample of three Universities offering technical teacher programme was used for the study. Components of the technical teacher education curriculum in each institution were ...

  15. Component Rhinoplasty

    OpenAIRE

    Mohmand, Muhammad Humayun; Ahmad, Muhammad

    2014-01-01

    BACKGROUND According to statistics of American Society of Plastic Surgeons, cosmetic rhinoplasty was the second most frequently performed cosmetic surgery. This study shares the experiences with component rhinoplasty. METHODS From 2004 to 2010, all patients underwent aesthetic nasal surgery were enrolled. The patients requiring only correction of septal deviation and those presenting with cleft lip nasal deformity were excluded. All procedures were performed under general anaesthesia with ope...

  16. Hyperfrequency components

    Science.gov (United States)

    1994-09-01

    The document has a collection of 19 papers (11 on technologies, 8 on applications) by 26 authors and coauthors. Technological topics include: evolution from conventional HEMT's double heterojunction and planar types of pseudomorphic HEMT's; MMIC R&D and production aspects for very-low-noise, low-power, and very-low-noise, high-power applications; hyperfrequency CAD tools; parametric measurements of hyperfrequency components on plug-in cards for design and in-process testing uses; design of Class B power amplifiers and millimetric-wave, bigrid-transistor mixers, exemplifying combined use of three major types of physical simulation in electrical modeling of microwave components; FET's for power amplification at up to 110 GHz; production, characterization, and nonlinear applications of resonant tunnel diodes. Applications topics include: development of active modules for major European programs; tubes versus solid-state components in hyperfrequency applications; status and potentialities of national and international cooperative R&D on MMIC's and CAD of hyperfrequency circuitry; attainable performance levels in multifunction MMIC applications; state of the art relative of MESFET power amplifiers (Bands S, C, X, Ku); creating a hyperfrequency functions library, of parametrizable reference cells or macrocells; and design of a single-stage, low-noise, band-W amplifier toward development of a three-stage amplifier.

  17. The impact of fatigue on the non-technical skills performance of critical care air ambulance clinicians.

    Science.gov (United States)

    Myers, J A; Powell, D M C; Aldington, S; Sim, D; Psirides, A; Hathaway, K; Haney, M F

    2017-11-01

    The relationship between fatigue-related risk and impaired clinical performance is not entirely clear. Non-technical factors represent an important component of clinical performance and may be sensitive to the effects of fatigue. The hypothesis was that the sum score of overall non-technical performance is degraded by fatigue. Nineteen physicians undertook two different simulated air ambulance missions, once when rested, and once when fatigued (randomised crossover design). Trained assessors blinded to participants' fatigue status performed detailed structured assessments based on expected behaviours in four non-technical skills domains: teamwork, situational awareness, task management, and decision making. Participants also provided self-ratings of their performance. The primary endpoint was the sum score of overall non-technical performance. The main finding, the overall non-technical skills performance rating of the clinicians, was better in rested than fatigued states (mean difference with 95% CI, 2.8 [2.2-3.4]). The findings remained consistent across individual non-technical skills domains; also when controlling for an order effect and examining the impact of a number of possible covariates. There was no difference in self-ratings of clinical performance between rested and fatigued states. Non-technical performance of critical care air transfer clinicians is degraded when they are fatigued. Fatigued clinicians may fail to recognise the degree to which their performance is compromised. These findings represent risk to clinical care quality and patient safety in the dynamic and isolated environment of air ambulance transfer. © 2017 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  18. The All-DQ-Domain EMTP

    Directory of Open Access Journals (Sweden)

    Gibson H.M. Sianipar

    2011-04-01

    Full Text Available This paper presents an improvement to dq-domain method of calculating electromagnetic transients. The proposed methodology works on dq-domain model for all components of the power system and during all time iterations. This is a new direction distinct from the old one where the network is invariably modeled in phase-domain. By modeling the network in dq-domain there is no more problem of interfacing machine to network as usually met in the existing method as machine is modeled invariably in dq-domain. Besides eliminating the time consuming transformation procedure between dq-domain to phase-domain or visa versa the new method is able now to fully exploit the infinite stability region of the trapezoidal rule of integration. The prediction/correction procedure of the conventional dq-domain method, which is notoriously known limiting the stability region, is no longer required. Comparing simulations using the new method and ATP, one of the conventional dq-domain version, show perfect conformity for small time step. For long time step while ATP is failing, the new method still converges accurately up to Nyquist’s interval.

  19. Consolidated incineration facility technical support

    International Nuclear Information System (INIS)

    Burns, D.; Looper, M.G.

    1993-01-01

    In 1996, the Savannah River Site plans to begin operation of the Consolidated Incineration Facility (CIF) to treat solid and liquid RCRA hazardous and mixed wastes. The Savannah River Technology Center (SRTC) leads an extensive technical support program designed to obtain incinerator and air pollution control equipment performance data to support facility start-up and operation. Key components of this technical support program include recently completed waste burn tests at both EPA's Incineration Research Facility and at Energy and Environmental Research Corporation's Solid Waste Incineration Test Facility. The main objectives for these tests were determining the fate of heavy metals, measuring organics destruction and removal efficiencies, and quantifying incinerator offgas particulate loading and size distribution as a function of waste feed characteristics and incineration conditions. In addition to these waste burning tests, the SRTC has recently completed installations of the Offgas Components Test Facility (OCTF), a 1/10 scale CIF offgas system pilot plant. This pilot facility will be used to demonstrate system operability and maintainability, evaluate and optimize equipment and instrument performance, and provide direct CIF start-up support. Technical support programs of this type are needed to resolve technical issues related with treatment and disposal of combustible hazardous, mixed, and low-level radioactive waste. Implementation of this program will minimize facility start-up problems and help insure compliance with all facility performance requirements

  20. Variance Components

    CERN Document Server

    Searle, Shayle R; McCulloch, Charles E

    1992-01-01

    WILEY-INTERSCIENCE PAPERBACK SERIES. The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists. ". . .Variance Components is an excellent book. It is organized and well written, and provides many references to a variety of topics. I recommend it to anyone with interest in linear models.".

  1. Rigorous Specification and Low-Latency Implementation of Technical Market Indicators

    OpenAIRE

    Bakanov, Konstantin; Spence, Ivor; Vandierendonck, Hans; Gillan, Charles J

    2014-01-01

    Technical market indicators are tools used by technical an- alysts to understand trends in trading markets. Technical (market) indicators are often calculated in real-time, as trading progresses. This paper presents a mathematically- founded framework for calculating technical indicators. Our framework consists of a domain specific language for the un- ambiguous specification of technical indicators, and a run- time system based on Click, for computing the indicators. We argue that our soluti...

  2. Progress report : Technical Physics Division

    International Nuclear Information System (INIS)

    Gopalaraman, C.P.; Deshpande, R.Y.

    1978-01-01

    The research and development work carried out in the Technical Physics Division of the Bhabha Atomic Research Centre, Bombay, is reported. Some of the achievements are: (1) fabrication of mass spectrometers for heavy water analysis and lithium 6/7 isotope ratio measurement, (2) fabrication of electronic components for mass spectrometers, (3) growing of sodium iodide crystals for radiation detectors, (4) development of sandwich detectors comprising of NaI(Tl) and CaI(Na), (5) fabrication of mass spectrometer type leak detectors and (6) fabrication of the high vacuum components of the vacuum system of the variable energy cyclotron based at Calcutta. (M.G.B.)

  3. Strategy of technical innovation

    International Nuclear Information System (INIS)

    Lee, Ga Jong

    1990-12-01

    This book deals with policy of scientific technique and technical innovation such as research for development and types of technical innovation, historical development and process of technical innovation, economic growth, technology change and investment for research and development, structure and form of technical transfer with the meaning process, from, structure and theory, economic growth and investment of research and development with experiential analysis and case study on strategy of technical innovation in electron and fine chemical industry.

  4. Flexible time domain averaging technique

    Science.gov (United States)

    Zhao, Ming; Lin, Jing; Lei, Yaguo; Wang, Xiufeng

    2013-09-01

    Time domain averaging(TDA) is essentially a comb filter, it cannot extract the specified harmonics which may be caused by some faults, such as gear eccentric. Meanwhile, TDA always suffers from period cutting error(PCE) to different extent. Several improved TDA methods have been proposed, however they cannot completely eliminate the waveform reconstruction error caused by PCE. In order to overcome the shortcomings of conventional methods, a flexible time domain averaging(FTDA) technique is established, which adapts to the analyzed signal through adjusting each harmonic of the comb filter. In this technique, the explicit form of FTDA is first constructed by frequency domain sampling. Subsequently, chirp Z-transform(CZT) is employed in the algorithm of FTDA, which can improve the calculating efficiency significantly. Since the signal is reconstructed in the continuous time domain, there is no PCE in the FTDA. To validate the effectiveness of FTDA in the signal de-noising, interpolation and harmonic reconstruction, a simulated multi-components periodic signal that corrupted by noise is processed by FTDA. The simulation results show that the FTDA is capable of recovering the periodic components from the background noise effectively. Moreover, it can improve the signal-to-noise ratio by 7.9 dB compared with conventional ones. Experiments are also carried out on gearbox test rigs with chipped tooth and eccentricity gear, respectively. It is shown that the FTDA can identify the direction and severity of the eccentricity gear, and further enhances the amplitudes of impulses by 35%. The proposed technique not only solves the problem of PCE, but also provides a useful tool for the fault symptom extraction of rotating machinery.

  5. Component reliability for electronic systems

    CERN Document Server

    Bajenescu, Titu-Marius I

    2010-01-01

    The main reason for the premature breakdown of today's electronic products (computers, cars, tools, appliances, etc.) is the failure of the components used to build these products. Today professionals are looking for effective ways to minimize the degradation of electronic components to help ensure longer-lasting, more technically sound products and systems. This practical book offers engineers specific guidance on how to design more reliable components and build more reliable electronic systems. Professionals learn how to optimize a virtual component prototype, accurately monitor product reliability during the entire production process, and add the burn-in and selection procedures that are the most appropriate for the intended applications. Moreover, the book helps system designers ensure that all components are correctly applied, margins are adequate, wear-out failure modes are prevented during the expected duration of life, and system interfaces cannot lead to failure.

  6. Technical Training Seminar

    CERN Multimedia

    2003-01-01

    Thursday 4 September From 14:00 to 17:00 - Training Centre Auditorium bldg. 593, room 11 The Summit Design VisualElite 4.0 Release Jean Marie St Paul / SUMMIT DESIGN, Europe, Technical Manager Michel Delcroix / SUMMIT DESIGN, Southern Europe, Sales F-95015 CERGY PONTOISE, France Summit Design is an important EDA digital hardware design tool supplier, and the industry leader in the emerging Electronic System Level design domain. Its VisualElite program has been used at CERN for several years. This seminar will include the highlights of the program's latest release. It will be illustrated how Summit Design products can provide a high-level C/C++ and SystemC functional modelling design and verification environment, enabling engineers to analyse system concepts before the implementation stage. The seminar will show how mixed SystemC and HDL simulation can be done, along with solutions for hardware/software development. • HDL new features: Connectivity Table Editor. Xemacs full integration. New NCsi...

  7. Technical Training Seminar

    CERN Multimedia

    2003-01-01

    Thursday 4 September From 14:00 to 17:00 - Training Centre Auditorium bldg. 593, room 11 The Summit Design VisualElite 4.0 Release Jean Marie St Paul / SUMMIT DESIGN, Europe, Technical Manager Michel Delcroix / SUMMIT DESIGN, Southern Europe, Sales F-95015 CERGY PONTOISE, France Summit Design is an important EDA digital hardware design tool supplier, and the industry leader in the emerging Electronic System Level design domain. Its VisualElite program has been used at CERN for several years. This seminar will include the highlights of the program's latest release. It will be illustrated how Summit Design products can provide a high-level C/C++ and SystemC functional modelling design and verification environment, enabling engineers to analyse system concepts before the implementation stage. The seminar will show how mixed SystemC and HDL simulation can be done, along with solutions for hardware/software development. • HDL new features: Connectivity Table Editor. Xemacs full integration. New NCsim ...

  8. A review and evaluation of the Langley Research Center's Scientific and Technical Information Program: Results of phase 6: The technical report. A survey and analysis

    Science.gov (United States)

    Mccullough, R. A.; Pinelli, T. E.; Pilley, D. D.; Stohrer, F. F.

    1982-01-01

    Current practice and usage using selected technical reports; literature relative to the sequential, language, and presentation components of technical reports; and NASA technical report publications standards are discussed. The effctiveness of the technical report as a product for information dissemination is considered.

  9. Domain Theory for Concurrency

    DEFF Research Database (Denmark)

    Nygaard, Mikkel

    Concurrent computation can be given an abstract mathematical treatment very similar to that provided for sequential computation by domain theory and denotational semantics of Scott and Strachey. A simple domain theory for concurrency is presented. Based on a categorical model of linear logic and ...... towards more expressive languages than HOPLA and Affine HOPLA—in particular concerning extensions to cover independence models. The thesis concludes with a discussion of related work towards a fully fledged domain theory for concurrency....

  10. Learning and Domain Adaptation

    Science.gov (United States)

    Mansour, Yishay

    Domain adaptation is a fundamental learning problem where one wishes to use labeled data from one or several source domains to learn a hypothesis performing well on a different, yet related, domain for which no labeled data is available. This generalization across domains is a very significant challenge for many machine learning applications and arises in a variety of natural settings, including NLP tasks (document classification, sentiment analysis, etc.), speech recognition (speakers and noise or environment adaptation) and face recognition (different lighting conditions, different population composition).

  11. Technical efficiency, efficiency change, technical progress and ...

    African Journals Online (AJOL)

    Technical efficiency, efficiency change, technical progress and productivity growth in the national health systems of continental African countries. ... a view to analysing changes in efficiency and changes in technology. The analysis was based on a five-year panel data (1999-2003) from all the 53 countries of continental ...

  12. Supersymmetric domain walls

    NARCIS (Netherlands)

    Bergshoeff, Eric A.; Kleinschmidt, Axel; Riccioni, Fabio

    2012-01-01

    We classify the half-supersymmetric "domain walls," i.e., branes of codimension one, in toroidally compactified IIA/IIB string theory and show to which gauged supergravity theory each of these domain walls belong. We use as input the requirement of supersymmetric Wess-Zumino terms, the properties of

  13. Quantum Bounded Symmetric Domains

    OpenAIRE

    Vaksman, L. L.

    2008-01-01

    This is Leonid Vaksman's monograph "Quantum bounded symmetric domains" (in Russian), preceded with an English translation of the table of contents and (a part) of the introduction. Quantum bounded symmetric domains are interesting from several points of view. In particular, they provide interesting examples for noncommutative complex analysis (i.e., the theory of subalgebras of C^*-algebars) initiated by W. Arveson.

  14. Has Technical Communication Arrived as a Profession

    OpenAIRE

    Pringle, Kathy; Williams, Sean

    2005-01-01

    This article examines the design and technology components of technical communication by investigating how practitioners imagine their work and the profession, specifically with respect to technology. In short, we wanted to interrogate the duality of “core design skills” and “technology skills” by asking practitioners to reflect both on the definition of technical communication and on the role technology plays in their work. We wanted to weigh claims that communication and rhetorical skills a...

  15. Cholesterol Domains Enhance Transfection

    Science.gov (United States)

    Betker, Jamie L.; Kullberg, Max; Gomez, Joe; Anchordoquy, Thomas J.

    2014-01-01

    The formation of cholesterol domains in lipoplexes has been associated with enhanced serum stability and transfection rates both in cell culture and in vivo. This study utilizes the ability of saturated phosphatidylcholines to promote the formation of cholesterol domains at much lower cholesterol contents than have been utilized in previous work. The results show that lipoplexes with identical cholesterol and cationic lipid contents exhibit significantly improved transfection efficiencies when a domain is present, consistent with previous work. In addition, studies assessing transfection rates in the absence of serum demonstrate that the ability of domains to enhance transfection is not dependent on interactions with serum proteins. Consistent with this hypothesis, characterization of the adsorbed proteins composing the corona of these lipoplex formulations did not reveal a correlation between transfection and the adsorption of a specific protein. Finally, we show that the interaction with serum proteins can promote domain formation in some formulations, and thereby result in enhanced transfection only after serum exposure. PMID:23557286

  16. How to be an Effective Technical Writer?

    Directory of Open Access Journals (Sweden)

    M Solaiman Ali

    2012-07-01

    Full Text Available Abstract--This paper has focused on technical writing as a skill for engineers. It has sought to define technical writing and throw light on the content and technique of writing the various components of successful technical reports (for example, articles, papers, or research reports, such as theses and dissertations. Then, it has highlighted other special features and principles of effective technical writing. The material in this paper is divided into seven major parts. Part 1 (Technical writing for engineers stresses that a successful engineering career requires strong writing skills. Part 2 (How to write the major sections or elements of a report describes the techniques of writing the abstract, introduction, literature review, procedure/methods & materials, results, discussion, conclusion, and recommendations. Part 3 (Special features of technical writing brings into focus some of the special features of technical writing such as tables & graphs in the text, graphics in instructions, team writing, ethics (plagiarism, document sources, three citation styles and IEEE reference style. Part 4 (Technical usage deals with writing abbreviations, initialisms and acronyms, numbers, units of measurement, and equations.Part 5 (Technical style highlights the imperative writing style and other features of technical writing such as the use of active and passive voices, plain vs. complex syntax, avoiding redundant or superfluous expressions, and vague generalities, using words or expressions with visual impact, the past tense to describe experimental work, the present tense to describe hypotheses, principles, theories and truths, and breaking up the text of the report into short sections. Part 6 (Document specifications emphasizes the technical writer’s need to conform to such document specifications as word count, format, font, number of words per line of text imposed. Part 7 (Reader-friendly technical writing suggests choosing the varied writing modes

  17. Technical training: places available

    CERN Multimedia

    2013-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tel: 74924)

  18. Technical training - places available

    CERN Multimedia

    2013-01-01

    If you would like more information on a course, or have any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tel: 74924)

  19. Technical training: places available

    CERN Multimedia

    2014-01-01

    If you would like more information on a course, or have any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Marie Lahchimi, Technical Training Administration (Tel: 74924)

  20. Technical training: places available

    CERN Multimedia

    2014-01-01

    If you would like more information on a course, or have any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tel: 74924)

  1. Technical training: places available

    CERN Multimedia

    2013-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch. Eva Stern and Elise Romero, Technical Training Administration (Tél : 74924)  

  2. Technical Assistance Plan (TAP)

    Science.gov (United States)

    A Technical Assistance Plan (TAP) enables community groups to retain the services of an independent technical advisor and to provide resources for a community group to help inform other community members about site decisions.

  3. Inventorying and Assessing Cyberinfrastructure Readiness for Cross-Domain Information Re-use in the Geosciences: a Perspective from Hydrology (Invited)

    Science.gov (United States)

    Zaslavsky, I.; Valentine, D. W.; Richard, S. M.; Lehnert, K. A.; Couch, A.

    2013-12-01

    Hydrologic analysis and modeling increasingly requires information from other fields, including weather and climate research, geochemistry, lithology, soil studies, geomorphology and land use, while researchers from other disciplines often rely on hydrologic data to analyze and model phenomena. Enabling scientific collaboration across traditional domain boundaries, and making information re-use across disciplines technically feasible and scientifically sound, is a key goal of a new research initiative of the U.S. National Science Foundation, called EarthCube. We discuss challenges and approaches to cross-domain interoperability in the geosciences and offer a model for assessing 'interoperability-readiness' of domain information systems. The model provides a methodology and criteria for evaluating efficiency and ease of automated discovery, interpretation, access and integration of information within domain cyberinfrastructures. In the initial assessment we consider four basic infrastructure components: metadata catalogs that provide standard discovery services over datasets and other domain resources; vocabularies that support unambiguous interpretation of domain resources and metadata; services that enable programmatic access to information repositories; and formal domain information models. A significant barrier to interoperability exists due to a considerable variety in protocols and encodings across domain information systems, despite the fact that general standards for these components have been proposed, e.g. Open Geospatial Consortium (OGC) Catalog Services for the Web (CSW) for interoperable catalogs, Simple Knowledge Organization System (SKOS) for vocabularies, OGC Sensor Observation Service (SOS) for requesting observational data, and OGC Observations and Measurements as a general information model and data exchange encoding. To assess this diversity of implementations, we developed an initial inventory of key information system components from geoscience

  4. The general technical regulation and the standardization

    International Nuclear Information System (INIS)

    Laverie, Michel; Houze, Christian; Lebouleux, Philippe

    1980-01-01

    Through a certain number of procedures, the thorough appreciation of the safety of a nuclear installation relies more on a specific appreciation taking into account the references as a whole, than on a technical regulation which claims to cover all the problems. Nevertheless, a French technical regulation structure regarding the safety domain must be built up progressively. The authors consider the principles of such a structure, and together they make the inventory of the works, finished, in progress or contemplated. The description of this specifically French approach emphazises the multiple and complementary forms given to statutory implements [fr

  5. Teaching Technical Writing - Towards Technical Writing

    DEFF Research Database (Denmark)

    Kastberg, Peter

    2000-01-01

    In this paper I will present key aspects of the curriculum for the university degree in technical translation that I have designed for and subsequently implemented at the German Department of the Aarhus School of Business, Denmark. My starting point will be a critical discussion of the norm...... that used to govern what the quality of an LSP text should be as opposed to the standpoint, which I advocate. By way of summing up, I will show how a university curriculum is designed so that - upon graduation - the technical translator could also be methodological quite well suited to take on the challenge...... of technical writing....

  6. Shaking table testing of mechanical components

    International Nuclear Information System (INIS)

    Jurukovski, D.; Taskov, Lj.; Mamucevski, D.; Petrovski, D.

    1995-01-01

    Presented is the experience of the Institute of Earthquake Engineering and Engineering Seismology, Skopje, Republic of Macedonia in seismic qualification of mechanical components by shaking table testing. Technical data and characteristics for the three shaking tables available at the Institute are given. Also, for characteristic mechanical components tested at the Institute laboratories, basic data such as producer, testing investor, description of the component, testing regulation, testing equipment and final user of the results. (author)

  7. Fatou components with punctured limit sets

    NARCIS (Netherlands)

    Boc-Thaler, L.; Fornæss, J.E.; Peters, H.

    2015-01-01

    We study invariant Fatou components for holomorphic endomorphisms in P 2 . In the recurrent case these components were classified by Fornæss and Sibony [Classification of recurrent domains for some holomorphic maps. Math. Ann. 301(4) (1995), 813-820]. Ueda [Holomorphic maps on projective spaces and

  8. FLAMMABLE GAS TECHNICAL BASIS DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    KRIPPS, L.J.

    2005-02-18

    This document describes the qualitative evaluation of frequency and consequences for double shell tank (DST) and single shell tank (SST) representative flammable gas accidents and associated hazardous conditions without controls. The evaluation indicated that safety-significant SSCs and/or TSRS were required to prevent or mitigate flammable gas accidents. Discussion on the resulting control decisions is included. This technical basis document was developed to support of the Tank Farms Documented Safety Analysis (DSA) and describes the risk binning process for the flammable gas representative accidents and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous condition based on an evaluation of the event frequency and consequence.

  9. Linac4 Technical Design Report

    CERN Document Server

    Arnaudon, L; Baylac, M; Bellodi, G; Body, Y; Borburgh, J; Bourquin, P; Broere, J; Brunner, O; Bruno, L; Carli, C; Caspers, Friedhelm; Cousineau, S M; Cuvet, Y; De Almeida Martins, C; Dobers, T; Fowler, T; Garoby, R; Gerigk, F; Goddard, B; Hanke, K; Hori, M; Jones, M; Kahle, K; Kalbreier, Willi; Kroyer, T; Küchler, D; Lombardi, A M; López-Hernandez, L A; Magistris, M; Martini, M; Maury, S; Page, E; Paoluzzi, M; Pasini, M; Raich, U; Rossi, C; Royer, J P; Sargsyan, E; Serrano, J; Scrivens, R; Silari, M; Timmins, M; Venturini-Delsolaro, W; Vretenar, M; Wegner, R; Weterings, W; Zickler, T

    2006-01-01

    Linac4 is an H- linear accelerator, intended to replace Linac2 as injector to the PS Booster (PSB). By delivering to the PSB a beam at 160 MeV energy, Linac4 will provide the conditions to double the brightness and intensity of the beam from the PSB, thus removing the first bottleneck towards higher brightness for the LHC and simplifying operation. Moreover, this new linac constitutes an essential component of any of the envisaged LHC upgrade scenarios and could open the way to future extensions of the CERN accelerator complex towards higher performance. This Technical Design Report presents a detailed technical overview of the Linac4 design as it stands at end 2006.

  10. Conserved Domain Database (CDD)

    Data.gov (United States)

    U.S. Department of Health & Human Services — CDD is a protein annotation resource that consists of a collection of well-annotated multiple sequence alignment models for ancient domains and full-length proteins.

  11. Components of the Profitability of Technical Currency Trading

    OpenAIRE

    Schulmeister, Stephan

    2005-01-01

    This paper investigates the sources of the profitability of 1024 moving average and momentum models when trading in the German mark (euro)/U.S. dollar market based on daily data. The main results are as follows. First, each of these models would have been profitable over the entire sample period. Second, this profitability is exclusively due to the exploitation of persistent exchange rate trends. Third, these results do not change substantially when trading is examined within subperiods. Four...

  12. Microgrid Design Toolkit (MDT) Technical Documentation and Component Summaries

    Energy Technology Data Exchange (ETDEWEB)

    Arguello, Bryan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Katherine A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Eddy, John P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    The Microgrid Design Toolkit (MDT) is a decision support software tool for microgrid designers to use during the microgrid design process. The models that support the two main capabilities in MDT are described. The first capability, the Microgrid Sizing Capability (MSC), is used to determine the size and composition of a new microgrid in the early stages of the design process. MSC is a mixed-integer linear program that is focused on developing a microgrid that is economically viable when connected to the grid. The second capability is focused on refining a microgrid design for operation in islanded mode. This second capability relies on two models: the Technology Management Optimization (TMO) model and Performance Reliability Model (PRM). TMO uses a genetic algorithm to create and refine a collection of candidate microgrid designs. It uses PRM, a simulation based reliability model, to assess the performance of these designs. TMO produces a collection of microgrid designs that perform well with respect to one or more performance metrics.

  13. Center for Center for Technology for Advanced Scientific Component Software (TASCS)

    Energy Technology Data Exchange (ETDEWEB)

    Kostadin, Damevski [Virginia State Univ., Petersburg, VA (United States)

    2015-01-25

    A resounding success of the Scientific Discovery through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedented computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS)1 tackles these these issues by exploiting component-based software development to facilitate collaborative high-performance scientific computing.

  14. Center for Technology for Advanced Scientific Component Software (TASCS) Consolidated Progress Report July 2006 - March 2009

    Energy Technology Data Exchange (ETDEWEB)

    Bernholdt, D E; McInnes, L C; Govindaraju, M; Bramley, R; Epperly, T; Kohl, J A; Nieplocha, J; Armstrong, R; Shasharina, S; Sussman, A L; Sottile, M; Damevski, K

    2009-04-14

    A resounding success of the Scientific Discovery through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedented computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS) tackles these issues by exploiting component-based software development to facilitate collaborative high-performance scientific computing.

  15. Towards Domain-specific Flow-based Languages

    DEFF Research Database (Denmark)

    Zarrin, Bahram; Baumeister, Hubert; Sarjoughian, Hessam S.

    2018-01-01

    describe their problems and solutions, instead of using general purpose programming languages. The goal of these languages is to improve the productivity and efficiency of the development and simulation of concurrent scientific models and systems. Moreover, they help to expose parallelism and to specify...... the concurrency within a component or across different independent components. In this paper, we introduce the concept of domain-specific flowbased languages which allows domain experts to use flow-based languages adapted to a particular problem domain. Flow-based programming is used to support concurrency, while......Due to the significant growth of the demand for data-intensive computing, in addition to the emergence of new parallel and distributed computing technologies, scientists and domain experts are leveraging languages specialized for their problem domain, i.e., domain-specific languages, to help them...

  16. DRDC Technical Stream Integrated Capabilities and Vision

    Science.gov (United States)

    2011-09-01

    developed as part of this process: “To impact Defence and Security and enable the DRDC S&T program as technical leaders and integral partners...capacités existantes : • Expertise multidisciplinaire dans des domaines techniques et humains ; • Expertise à l’égard de l’infrastructure...Strategy: Science and Technology for a Secure Canada (2006) DRDC Toronto TM 2011-017 3 integrated capabilities and the impact these

  17. Technical approach to aging management

    International Nuclear Information System (INIS)

    Vora, J.P.; Johnson, A.B. Jr.; Allen, R.P.

    1992-10-01

    Systematic and effective control of age-related degradation of safety-related components, systems, and structures in nuclear power plants (NPPs) is an important challenge to plant operators. Several data bases, available to provide guidance on aging management, are summarized. However, the ultimate consideration is: How effectively is aging management being implemented at individual plants? Illustrated here is a specific strategy that served to develop the technical data base for the Nuclear Plant Aging Research Program. The strategy is comprehensive, systematic, and adaptable. Effective aging management at NPPs could be facilitated by a parallel strategy. The elements of a strategy are suggested

  18. Distant relationships amongst protein domains

    Indian Academy of Sciences (India)

    ncbs

    3. Small domains. The 'pleckstrin homology' (PH) domain is a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton.

  19. Assessment of technical and nontechnical skills in surgical residents.

    Science.gov (United States)

    Ponton-Carss, Alicia; Kortbeek, John B; Ma, Irene W Y

    2016-11-01

    Surgical competence encompasses both technical and nontechnical skills. This study seeks to evaluate the validity evidence for a comprehensive surgical skills examination and to examine the relationship between technical and nontechnical skills. Six examination stations assessing both technical and nontechnical skills, conducted yearly for surgical trainees (n = 120) between 2010 and 2014 are included. The assessment tools demonstrated acceptable internal consistency. Interstation reliability for technical skills was low (alpha = .39). Interstation reliability for the nontechnical skills was lower (alpha range -.05 to .31). Nontechnical skills domains were strongly correlated, ranging from r = .65, P technical skills were inconsistent, ranging from poor (r = -.06; P = .54) to moderate (r = .45; P technical and nontechnical skills are necessary to assess overall surgical competency. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Gravitational field of spherical domain wall in higher dimension

    Indian Academy of Sciences (India)

    An exact solution of Einstein's equations is found describing the gravitational field of a spherical domain wall with nonvanishing stress component in the direction perpendicular to the plane of the wall. Also we have studied the motion of test particle around the domain wall.

  1. Nucleoelectric plants technical memory

    International Nuclear Information System (INIS)

    Araujo Pereira, Alvaro de

    1991-01-01

    The work explains the basic norms that establish the guidelines to the Technical Memory elaboration of this electrical energy sector - the nucleoelectric plants. It guides the technicians who execute the Technical Memory of the plants, exposing the items that may compose the work: contents: introduction, planning, proposition, equipment and materials supply, construction, commissioning, commercial actions, budget, financing and costs; generalities: drawings and photographies, monetary references, terminology, system units, management, graphic guide project, responsible staff, a summarized technical card and illustrations

  2. Clojure for domain-specific languages

    CERN Document Server

    Kelker, Ryan D

    2013-01-01

    An example-oriented approach to develop custom domain-specific languages.If you've already developed a few Clojure applications and wish to expand your knowledge on Clojure or domain-specific languages in general, then this book is for you. If you're an absolute Clojure beginner, then you may only find the detailed examples of the core Clojure components of value. If you've developed DSLs in other languages, this Lisp and Java-based book might surprise you with the power of Clojure.

  3. Structural organization of the regulatory domain of human 5-lipoxygenase.

    Science.gov (United States)

    Allard, John B; Brock, Thomas G

    2005-04-01

    The enzyme 5-lipoxygenase (5-LO) initiates the synthesis of leukotrienes. For this reason, 5-LO activity is important for immune defense, whereas improper regulation contributes to pathogenesis, including chronic inflammation, asthma and atherosclerosis. Like all lipoxygenases, the 5-LO protein consists of two domains, a regulatory domain and a catalytic domain. Naturally, the regulatory domain determines catalytic activity and controls leukotriene synthesis. This domain shares features with classical C2 domains in that it has a beta-sandwich structure and binds calcium, nucleotides and phospholipids. However, important structural features place this domain in a distinct family, the PLATs (for Polycystin-1, Lipoxygenase, alpha-Toxin). In this review, we summarize our current understanding of the three dimensional organization of this important component of the 5-LO molecule. In addition, we point to findings from structural analyses of related proteins to suggest further details relating 5-LO structure to function.

  4. Domain-Specific Multimodeling

    DEFF Research Database (Denmark)

    Hessellund, Anders

    Enterprise systems are complex artifacts. They are hard to build, manage, understand, and evolve. Existing software development paradigms fail to properly address challenges such as system size, domain complexity, and software evolution when development is scaled to enterprise systems. We propose...... domain-specific multimodeling as a development paradigm to tackle these challenges in a language-oriented manner. The different concerns of a system are conceptually separated and made explicit as independent domain-specific languages. This approach increases productivity and quality by raising...... this coordination problem. By systematically identifying language interactions, we can specify a coordination model for the system. Specifically, we explicitly identify name bindings and references across language boundaries. We argue that such a coordination model facilitates consistency, navigation, and guidance...

  5. Functional interchangeability of late domains, late domain cofactors and ubiquitin in viral budding.

    Directory of Open Access Journals (Sweden)

    Maria Zhadina

    2010-10-01

    Full Text Available The membrane scission event that separates nascent enveloped virions from host cell membranes often requires the ESCRT pathway, which can be engaged through the action of peptide motifs, termed late (L- domains, in viral proteins. Viral PTAP and YPDL-like L-domains bind directly to the ESCRT-I and ALIX components of the ESCRT pathway, while PPxY motifs bind Nedd4-like, HECT-domain containing, ubiquitin ligases (e.g. WWP1. It has been unclear precisely how ubiquitin ligase recruitment ultimately leads to particle release. Here, using a lysine-free viral Gag protein derived from the prototypic foamy virus (PFV, where attachment of ubiquitin to Gag can be controlled, we show that several different HECT domains can replace the WWP1 HECT domain in chimeric ubiquitin ligases and drive budding. Moreover, artificial recruitment of isolated HECT domains to Gag is sufficient to stimulate budding. Conversely, the HECT domain becomes dispensable if the other domains of WWP1 are directly fused to an ESCRT-1 protein. In each case where budding is driven by a HECT domain, its catalytic activity is essential, but Gag ubiquitination is dispensable, suggesting that ubiquitin ligation to trans-acting proteins drives budding. Paradoxically, however, we also demonstrate that direct fusion of a ubiquitin moiety to the C-terminus of PFV Gag can also promote budding, suggesting that ubiquitination of Gag can substitute for ubiquitination of trans-acting proteins. Depletion of Tsg101 and ALIX inhibits budding that is dependent on ubiquitin that is fused to Gag, or ligated to trans-acting proteins through the action of a PPxY motif. These studies underscore the flexibility in the ways that the ESCRT pathway can be engaged, and suggest a model in which the identity of the protein to which ubiquitin is attached is not critical for subsequent recruitment of ubiquitin-binding components of the ESCRT pathway and viral budding to proceed.

  6. Aspectos técnicos da cateterização do seio coronariano baseada no componente atrial do eletrograma intracavitário e anatomia radiológica durante o procedimento de implante de marcapasso biventricular Technical aspects of coronary sinus catheterization based on the atrial component of the intracavitary electrogram and radiological anatomy during the implantation procedure of a biventricular pacemaker

    Directory of Open Access Journals (Sweden)

    Fernando Sérgio Oliva de Souza

    2006-04-01

    Full Text Available OBJETIVO: Apresentar uma proposição técnica baseada na experiência de 130 implantes utilizando técnica simplificada para cateterização do seio coronariano, baseada no componente atrial do eletrograma intracavi-tário e anatomia radiológica. MÉTODOS: De outubro de 2001 a outubro de 2004 foram realiza-dos 130 implantes de marcapasso biventricular, utilizando-se anatomia radiológica e observação de eletrograma intracavitário, com prioridade ao componente atrial. RESULTADOS: O implante do sistema, utilizando-se a estimulação do ventrículo esquerdo via seio coronariano, não foi possível em 8 pacientes. Em 12 pacientes foram observadas dificuldades na canulação do óstio coronário e em 15 pacientes observaram-se dificuldades de progressão do eletrodo através do seio coronariano. O tempo médio de utilização de radioscopia foi de 18,69 min. CONCLUSÃO: A técnica de implante, utilizando a morfologia do componente atrial do eletrograma intracavitário e anatomia radiológica, demonstrou ser pouco trabalhosa, segura e eficaz para canulação do óstio do seio coronariano, necessitando de reduzido tempo de radioscopia.OBJECTIVE: To present a technical proposal based on the experience of 130 implantations using a simplified technique for coronary sinus catheterization, based on the atrial component of the intracavitary electrogram and radiological anatomy. METHODS: From October, 2001 to October, 2004, 130 biventricular pacemaker implantations were performed, using radiological anatomy and observation of the intracavitary electrogram, focusing on the atrial component. RESULTS: The implantation of the system using left ventricular pacing via coronary sinus was not possible in 8 patients. Difficulties on the cannulation of the coronary ostium were felt in 12 patients and difficulties of lead advancement through the coronary sinus were felt in 15 patients. The mean time of radioscopy utilization was 18.69 min. CONCLUSION: The

  7. Collaborating for Success: Team Teaching the Engineering Technical Thesis

    Science.gov (United States)

    Keating, Terrence; Long, Mike

    2012-01-01

    This paper will examine the collaborative teaching process undertaken at College of the North Atlantic-Qatar (CNA-Q) by Engineering and the Communication faculties to improve the overall quality of engineering students' capstone projects known as the Technical Thesis. The Technical Thesis is divided into two separate components: a proposal stage…

  8. Financial Statement Audit Report of Guilford Technical Community College.

    Science.gov (United States)

    Campbell, Ralph

    This report presents the results of the Guilford Technical Community College financial statement audit for the fiscal year ending on June 30, 1998. Guilford Technical Community College is a component of the State of North Carolina, thus the authority to audit is granted by Article 5A of G.S. 147. The accounts and operations of the institution were…

  9. The Agency's technical co-operation activities in 1993

    International Nuclear Information System (INIS)

    1994-08-01

    This document reviews the IAEA's Technical Cooperation activities for 1993. Apart from an overview, the report contains reviews by Agency programmes and technical divisions, by area, by component and by fund. Summaries of project implementation are also included, as well as indications of the achievements of projects completed in 1993

  10. Domain: Labour market

    NARCIS (Netherlands)

    Oude Mulders, J.; Wadensjö, E.; Hasselhorn, H.M.; Apt, W.

    This domain chapter is dedicated to summarize research on the effects of labour market contextual factors on labour market participation of older workers (aged 50+) and identify research gaps. While employment participation and the timing of (early) retirement is often modelled as an individual

  11. Normed Domains of Holomorphy

    Directory of Open Access Journals (Sweden)

    Steven G. Krantz

    2010-01-01

    Full Text Available We treat the classical concept of domain of holomorphy in ℂn when the holomorphic functions considered are restricted to lie in some Banach space. Positive and negative results are presented. A new view of the case n=1 is considered.

  12. Organisation, Quality and Challenges in the B. Ed Technical ...

    African Journals Online (AJOL)

    Technical) degree programme rated the organization and quality of the industrial attachment component of the programme. Challenges students faced during industrial attachment were also examined. A case study design was used. Twenty-five final ...

  13. Technical guidelines for environmental dredging of contaminated sediments

    Science.gov (United States)

    2008-09-01

    This report provides technical guidelines for evaluating : environmental dredging as a sediment remedy component. This document : supports the Contaminated Sediment Remediation Guidance for : Hazardous Waste Sites, released by the U.S. Environmental ...

  14. Technical Manual. The ACT®

    Science.gov (United States)

    ACT, Inc., 2014

    2014-01-01

    This manual contains technical information about the ACT® college readiness assessment. The principal purpose of this manual is to document the technical characteristics of the ACT in light of its intended purposes. ACT regularly conducts research as part of the ongoing formative evaluation of its programs. The research is intended to ensure that…

  15. TRANSLATING SERVICE TECHNICAL PROSE

    African Journals Online (AJOL)

    of technical literature: advertising agencies dealing with clients in the technical fields, workshops ..... editing, a subject specialist. (preferably a physician au fait with aerospace matters), and two good translators. Having all the resources at hand, the teams seclude themselves with all their allocated documents and the senior.

  16. Developing Technical Skill Assessments

    Science.gov (United States)

    Hyslop, Alisha

    2009-01-01

    One of the biggest challenges facing the career and technical education (CTE) community as it works to implement the 2006 Perkins Act is responding to more rigorous requirements for reporting on CTE students' technical skill attainment. The U.S. Department of Education suggested in non-regulatory guidance that states and locals use the number of…

  17. Summer Technical Students 2004

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    About 100 technical and doctoral students arrive each year, undergraduates and post-graduates who are preparing diploma or doctoral theses in applied science and technology. They spend up to two years at the Laboratory, as technical students as part of their formal training for a recognised degree or its equivalent.

  18. Transformation of technical infrastructure

    DEFF Research Database (Denmark)

    Nielsen, Susanne Balslev

    1998-01-01

    article about the need of new planning forums in order to initiate transformations with in management of large technical systems for energy, waste and water supply.......article about the need of new planning forums in order to initiate transformations with in management of large technical systems for energy, waste and water supply....

  19. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Glasser, Alan H. [Fusion Theory and Computation Inc., Kingston, WA (United States)

    2018-02-02

    Final technical report on DE-SC0016106. This is the final technical report for a portion of the multi-institutional CEMM project. This report is centered around 3 publications and a seminar presentation, which have been submitted to E-Link.

  20. Technical Training for Managers.

    Science.gov (United States)

    Haverland, Edgar M.

    The question has arisen as to what kind of information a manager without extensive technical training needs to learn to supervise effectively. For example, the Nike Hercules fire control platoon leader, usually an officer in his first active duty assignment, seldom has had extensive technical training. Yet he is responsibile for the…

  1. Technical Agency in Practice

    DEFF Research Database (Denmark)

    Krummheuer, Antonia Lina

    2015-01-01

    ) description of hybrid networks in which human and non-human actants are granted agency without differentiating different kinds of agency, EMCA focuses on the member's perspectives and the situated construction of technical agency that is made relevant within an ongoing interaction. Based on an EMCA analysis......The paper combines the discussion of technical agency and hybrid networks of Actor-Network Theory (ANT) with an ethnomethodological/conversation analytical (EMCA) perspective on situated practices in which participants ascribe agency to technical artefacts. While ANT works with (ethnographic...... of three video recordings of situations in which technical agency is made relevant by the human participants, the paper demonstrates different ways in which agency is granted to technical artefacts. Human participants can treat a technology as communication partner, as an active part (and actant...

  2. Chromatin domains and function

    NARCIS (Netherlands)

    Fransz, P.; Meier, I.

    2009-01-01

    The inheritance of biological traits involves not only the transfer of genetic information in the form of DNA, but also epigenetic information. The latter is encrypted in a DNA component, methylation of cytosine residues, and in non-DNA components such as histone modifications, non-histone proteins,

  3. OECD/NEA component operational experience, degradation and ageing project

    International Nuclear Information System (INIS)

    Gott, K.; Nevander, O.; Riznic, J.; Lydell, B.

    2015-01-01

    Several OECD Member Countries have agreed to establish the OECD/NEA 'Component Operational Experience, Degradation and Ageing Programme' (CODAP) to encourage multilateral co-operation in the collection and analysis of data relating to degradation and failure of metallic piping and non-piping metallic passive components in commercial nuclear power plants. The scope of the data collection includes service-induced wall thinning, part through-wall cracks, through-wall cracks with and without active leakage, and instances of significant degradation of metallic passive components, including piping pressure boundary integrity. CODAP is the continuation of the 2002-2011 'OECD/NEA Pipe Failure Data Exchange Project' (OPDE) and the Stress Corrosion Cracking Working Group of the 2006-2010 - OECD/NEA SCC and Cable Ageing project - (SCAP). OPDE was formally launched in May 2002. Upon completion of the 3. Term (May 2011), the OPDE project was officially closed to be succeeded by CODAP. In May 2011, 13 countries signed the CODAP first Term agreement. The first Term (2011-2014) work plan includes the development of a web-based relational event database on passive, metallic components in commercial nuclear power plants, a web-based knowledge base on material degradation, codes and standards relating to structural integrity and national practices for managing material degradation. The work plan also addresses the preparation of Topical Reports to foster technical cooperation and to deepen the understanding of national differences in ageing management. These Topical Reports are in the public domain and available for download on the NEA web site. Published in 2014, a first Topical Report addressed flow accelerated corrosion (FAC) of carbon steel and low alloy steel piping. A second Topical Report addresses operating experience with electro-hydraulic control (EHC) and instrument air (IA) system piping

  4. Human research ethics committees in technical universities.

    Science.gov (United States)

    Koepsell, David; Brinkman, Willem-Paul; Pont, Sylvia

    2014-07-01

    Human research ethics has developed in both theory and practice mostly from experiences in medical research. Human participants, however, are used in a much broader range of research than ethics committees oversee, including both basic and applied research at technical universities. Although mandated in the United States, the United Kingdom, Canada, and Australia, non-medical research involving humans need not receive ethics review in much of Europe, Asia, Latin America, and Africa. Our survey of the top 50 technical universities in the world shows that, where not specifically mandated by law, most technical universities do not employ ethics committees to review human studies. As the domains of basic and applied sciences expand, ethics committees are increasingly needed to guide and oversee all such research regardless of legal requirements. We offer as examples, from our experience as an ethics committee in a major European technical university, ways in which such a committee provides needed services and can help ensure more ethical studies involving humans outside the standard medical context. We provide some arguments for creating such committees, and in our supplemental article, we provide specific examples of cases and concerns that may confront technical, engineering, and design research, as well as outline the general framework we have used in creating our committee. © The Author(s) 2014.

  5. Pump Component Model in SPACE Code

    International Nuclear Information System (INIS)

    Kim, Byoung Jae; Kim, Kyoung Doo

    2010-08-01

    This technical report describes the pump component model in SPACE code. A literature survey was made on pump models in existing system codes. The models embedded in SPACE code were examined to check the confliction with intellectual proprietary rights. Design specifications, computer coding implementation, and test results are included in this report

  6. Studi Literatur Perubahan Antara CISSP 10 Domain Dengan 8 Domain

    OpenAIRE

    Perkasa, Michael; Noertjahyana, Agustinus; Rostianingsih, Silvia

    2016-01-01

    Degree is one that is being achieved by most people in their work, in order to influence the potential possessed by an employee or the employee. So with the development of technology, people increasingly need a degree or certification in order to hone and enhance its capabilities.With the changes under discussion on the differences of the 10 CISSP domains domain into 8 domains in each domain has the characteristics of each and their respective utility functions. CISSP 8 domain is a new domain...

  7. Time Domain Induced Polarization

    DEFF Research Database (Denmark)

    Fiandaca, Gianluca; Auken, Esben; Christiansen, Anders Vest

    2012-01-01

    Time-domain-induced polarization has significantly broadened its field of reference during the last decade, from mineral exploration to environmental geophysics, e.g., for clay and peat identification and landfill characterization. Though, insufficient modeling tools have hitherto limited the use...... of time-domaininduced polarization for wider purposes. For these reasons, a new forward code and inversion algorithm have been developed using the full-time decay of the induced polarization response, together with an accurate description of the transmitter waveform and of the receiver transfer function......%. Furthermore, the presence of low-pass filters in time-domain-induced polarization instruments affects the early times of the acquired decays (typically up to 100 ms) and has to be modeled in the forward response to avoid significant loss of resolution. The developed forward code has been implemented in a 1D...

  8. TENCompetence Domain Model

    NARCIS (Netherlands)

    2006-01-01

    This is the version 1.1 of the TENCompetence Domain Model (version 1.0 released at 19-6-2006; version 1.1 at 9-11-2008). It contains several files: a) a pdf with the model description, b) three jpg files with class models (also in the pdf), c) a MagicDraw zip file with the model itself, d) a release

  9. Book Review: New Perspectives on Technical Editing

    Science.gov (United States)

    Murphy, A. J. (Ed.); Sterken, Christiaan

    2012-08-01

    New Perspectives on Technical Editing by Avon J. Murphy (ed.) ISBN : 978-0895033949 (2010) Baywood Publishing Company Inc, Hardcover, 210 pages, 35.5 GBP This book presents a collection of 10 chapters dealing with diverse aspects of technical editing (ie, editorial planning, and analysis and structural changes made to other people's technological documents): research in technical editing, trends and teaching of technical editing, copyediting, and technical journal editing. The role and function of the modern journal and book editor is also dealt with in detail. Each chapter is written by an expert in the field: senior editors, university professors in technical communication, technical writers and linguists. The ever-evolving role of the editor is clearly elucidated in several historical reviews, and in the descriptions of the expectations for the future. A very striking aspect of this book is its extensive collection of bibliographic resources: every chapter lists dozens of very useful references, and the closing chapter, and annotated bibliography, contain many not so well known references, and are most useful. All in all, the book is a treasure trove listing more than 400 references, in addition to numerous webpage URLs embedded in the texts. The book is designed to help the reader to understand current practices and norms in technical editing, and to help to take action in editing as well as in teaching and educating would-be editors. The audience for this book thus includes editors and teachers, but also writers, researchers and students. A deep reading of this book will result in a better understanding of the difference between full technical editing and its much narrower component so well known as copyediting, and will convince any prospective editor that editing should not be undertaken if the people involved do not master the art of precision and accuracy in technical (as well as in human) communication, do not possess the technical know how and computer

  10. Cylinder components properties, applications, materials

    CERN Document Server

    2016-01-01

    Owing to the ever-increasing requirements to be met by gasoline and diesel engines in terms of CO2 reduction, emission behavior, weight, and service life, a comprehensive understanding of combustion engine components is essential today. It is no longer possible for professionals in automotive engineering to manage without the corresponding expertise, whether they work in the field of design, development, testing, or maintenance. This technical book provides in-depth answers to questions about design, production, and machining of cylinder components. In this second edition, every section has been revised and expanded to include the latest developments in the combustion engine. Content Piston rings Piston pins and piston pin circlips Bearings Connecting rods Crankcase and cylinder liners Target audience Engineers in the field of engine development and maintenanceLecturers and students in the areas of mechanical engineering, engine technology, and vehicle constructionAnyone interested in technology Publisher MAH...

  11. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Aristos Aristidou Natureworks); Robert Kean (NatureWorks); Tom Schechinger (IronHorse Farms, Mat); Stuart Birrell (Iowa State); Jill Euken (Wallace Foundation & Iowa State)

    2007-10-01

    The two main objectives of this project were: 1) to develop and test technologies to harvest, transport, store, and separate corn stover to supply a clean raw material to the bioproducts industry, and 2) engineer fermentation systems to meet performance targets for lactic acid and ethanol manufacturers. Significant progress was made in testing methods to harvest corn stover in a “single pass” harvest mode (collect corn grain and stover at the same time). This is technically feasible on small scale, but additional equipment refinements will be needed to facilitate cost effective harvest on a larger scale. Transportation models were developed, which indicate that at a corn stover yield of 2.8 tons/acre and purchase price of $35/ton stover, it would be unprofitable to transport stover more than about 25 miles; thus suggesting the development of many regional collection centers. Therefore, collection centers should be located within about 30 miles of the farm, to keep transportation costs to an acceptable level. These collection centers could then potentially do some preprocessing (to fractionate or increase bulk density) and/or ship the biomass by rail or barge to the final customers. Wet storage of stover via ensilage was tested, but no clear economic advantages were evident. Wet storage eliminates fire risk, but increases the complexity of component separation and may result in a small loss of carbohydrate content (fermentation potential). A study of possible supplier-producer relationships, concluded that a “quasi-vertical” integration model would be best suited for new bioproducts industries based on stover. In this model, the relationship would involve a multiyear supply contract (processor with purchase guarantees, producer group with supply guarantees). Price will likely be fixed or calculated based on some formula (possibly a cost plus). Initial quality requirements will be specified (but subject to refinement).Producers would invest in harvest

  12. Even-odd effects in magnetoresistance of ferromagnetic domain walls

    Science.gov (United States)

    Dzero, M.; Gor'kov, L. P.; Zvezdin, A. K.; Zvezdin, K. A.

    2003-03-01

    The difference in the density of states for the spin’s majority and minority bands in a ferromagnet changes the electrostatic potential along the domains, introducing discontinuities of the potential at domain boundaries. The value of the discontinuity oscillates with the number of domains. Discontinuity depends on the positions of domain walls, their motion, or the collapse of domain walls in applied magnetic field. Large values of the magnetoresistance are explained in terms of spin accumulation. We suggest a type of domain wall in nanowires made of itinerant ferromagnets, in which the magnetization vector changes without rotation. The absence of transverse magnetization components allows considerable spin accumulation, assuming the spin relaxation length LS is large enough.

  13. Technical standards in nuclear area

    International Nuclear Information System (INIS)

    Grimberg, M.

    1978-01-01

    The technical standardization in nuclear area is discussed. Also, the competence of CNEN in standardization pursuit is analysed. Moreover, the process of working up of technical standards is explained; in addition, some kinds of technical standards are discussed. (author) [pt

  14. Localization experience and future plan of NSLS primary components

    International Nuclear Information System (INIS)

    Kim, Haesoo

    1992-01-01

    Korea Heavy Industries and Construction Company is planning to obtain technical self-reliance of the component design, manufacturing and installation of the NSLS primary components as much as the target of 87% by 1995 as indicated in the technical self-reliance plan by the Korea Electric Power Company in 1988. In order to achieve this target, Koch has been involved in the component design, manufacturing and project management of the NSLS components from the early stage of the Young 3 and 4 project. In parallel, Koch has increased the self-reliance of the various fields taking full advantage of the technical documents, computer codes, training and consultation supplied by the technology transfer agreement. This paper presents the re-evaluation of the current status of technical self reliance as well as the make up plan to be implemented during the UCH 3 and 4 project for the area identified as the weakness

  15. Updating action domain descriptions.

    Science.gov (United States)

    Eiter, Thomas; Erdem, Esra; Fink, Michael; Senko, Ján

    2010-10-01

    Incorporating new information into a knowledge base is an important problem which has been widely investigated. In this paper, we study this problem in a formal framework for reasoning about actions and change. In this framework, action domains are described in an action language whose semantics is based on the notion of causality. Unlike the formalisms considered in the related work, this language allows straightforward representation of non-deterministic effects and indirect effects of (possibly concurrent) actions, as well as state constraints; therefore, the updates can be more general than elementary statements. The expressivity of this formalism allows us to study the update of an action domain description with a more general approach compared to related work. First of all, we consider the update of an action description with respect to further criteria, for instance, by ensuring that the updated description entails some observations, assertions, or general domain properties that constitute further constraints that are not expressible in an action description in general. Moreover, our framework allows us to discriminate amongst alternative updates of action domain descriptions and to single out a most preferable one, based on a given preference relation possibly dependent on the specified criteria. We study semantic and computational aspects of the update problem, and establish basic properties of updates as well as a decomposition theorem that gives rise to a divide and conquer approach to updating action descriptions under certain conditions. Furthermore, we study the computational complexity of decision problems around computing solutions, both for the generic setting and for two particular preference relations, viz. set-inclusion and weight-based preference. While deciding the existence of solutions and recognizing solutions are PSPACE-complete problems in general, the problems fall back into the polynomial hierarchy under restrictions on the additional

  16. Technical Report Writing Today

    DEFF Research Database (Denmark)

    Riordan, Daniel G.

    2014-01-01

    Section 1: Technical Communication Basics (8 chapters on tech com, audiences, tech com process, tech com style, researching, designing pages, using visual aids, describing). Section 2: Technical Communication Applications (7 chapters on sets of instructions, informal reports and email, developing...... websites/using social media, formal reports, recommendation and feasibility reports, proposals, user manuals). Section 3: Professional Communication (2 chapters and 2 appendices on presentations, job application materials, brief handbook for tech writers, documenting sources).......Section 1: Technical Communication Basics (8 chapters on tech com, audiences, tech com process, tech com style, researching, designing pages, using visual aids, describing). Section 2: Technical Communication Applications (7 chapters on sets of instructions, informal reports and email, developing...

  17. OSH technical reference manual

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    In an evaluation of the Department of Energy (DOE) Occupational Safety and Health programs for government-owned contractor-operated (GOCO) activities, the Department of Labor`s Occupational Safety and Health Administration (OSHA) recommended a technical information exchange program. The intent was to share written safety and health programs, plans, training manuals, and materials within the entire DOE community. The OSH Technical Reference (OTR) helps support the secretary`s response to the OSHA finding by providing a one-stop resource and referral for technical information that relates to safe operations and practice. It also serves as a technical information exchange tool to reference DOE-wide materials pertinent to specific safety topics and, with some modification, as a training aid. The OTR bridges the gap between general safety documents and very specific requirements documents. It is tailored to the DOE community and incorporates DOE field experience.

  18. Superfund Technical Assistance Grants

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes data related to the Superfund Technical Assistance Grant program, including grant number, award amounts, award dates, period of performance,...

  19. Technical report writing today

    CERN Document Server

    Riordan, Daniel G

    2014-01-01

    "Technical Report Writing Today" provides thorough coverage of technical writing basics, techniques, and applications. Through a practical focus with varied examples and exercises, students internalize the skills necessary to produce clear and effective documents and reports. Project worksheets help students organize their thoughts and prepare for assignments, and focus boxes highlight key information and recent developments in technical communication. Extensive individual and collaborative exercises expose students to different kinds of technical writing problems and solutions. Annotated student examples - more than 100 in all - illustrate different writing styles and approaches to problems. Numerous short and long examples throughout the text demonstrate solutions for handling writing assignments in current career situations. The four-color artwork in the chapter on creating visuals keeps pace with contemporary workplace capabilities. The Tenth Edition offers the latest information on using electronic resum...

  20. Socio-technical Betwixtness

    DEFF Research Database (Denmark)

    Bossen, Claus

    2017-01-01

    the intrinsically social and technical interwovenness of design, and the necessity of including affected people and stakeholders in the design process. This betwixtness of socio-technical design is demonstrated by the analysis of two IT systems for healthcare: a foundational model for electronic healthcare records......This chapter focusses on two challenges for socio-technical design: Having to choose between different rationales for design, and the adequate understanding and depiction of the work to be redesigned. These two challenges betwixt the otherwise strong tenets of socio-technical design of pointing out......, and an IT system organizing hospital porters’ work. The conceptual background for the analysis of the cases is provided by a short introduction to different rationales for organizational design, and by pointing to the differences between a linear, rationalistic versus an interactional depiction of work....

  1. Science and Technical Indicators

    Czech Academy of Sciences Publication Activity Database

    Laiblová Kadlecová, Ivana; Lhoták, Martin; Mika, Pavel

    -, č. 3 (2014) E-ISSN 1805-2800 Keywords : bibliometrics Subject RIV: AF - Documentation, Lib rarianship, Information Studies http://www. lib .cas.cz/casopis-informace/science-and-technical-indicators/

  2. NCDC Technical Reports

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NCDC Technical Reports is a set of retrospective analyses produced by the Research Customer Service Group and the National Climatic Data Center from 1995 to 2008....

  3. Assessing readiness of cyberinfrastructure resources for cross-domain interoperability: a view from an NSF EarthCube roadmap

    Science.gov (United States)

    Zaslavsky, Ilya; Couch, Alva; Richard, Stephen; Valentine, David; Lehnert, Kerstin; Stocks, Karen; Murphy, Philip

    2013-04-01

    EarthCube is a new research initiative of the U.S. National Science Foundation, with the mission to develop community-guided cyberinfrastructure integrating data, models and other resources across geoscience disciplines. Analysis and modeling of physical processes that are not confined to disciplinary or jurisdictional boundaries, requires that data and models can be re-used outside the original context in which they are collected or developed. Infrastructure readiness for cross-domain interoperability encompasses the capabilities that need to be in place to enable such information re-use and ensure that it is both scientifically sound and technically feasible. In an ideal cross-domain information integration scenario, resources can be discovered via federated catalogs and linked nomenclatures from neighboring domains, while standard data services can be used to transparently compile composite data products and to integrate information using commonality in key data characteristics related to shared models of spatial features, time measurements, and observations. The main premise of the cross-domain readiness assessment is that when accessing domain resources from another domain, a user expects to be able to discover these resources, interpret them, retrieve the information, and integrate it with other data. Documentation of the resource must be sufficient for a user in a different context to determine fitness for use, and establish trust in scientific soundness. As part of an EarthCube roadmap focused on cross-domain interoperability, we explored a number of approaches to cyberinfrastructure readiness assessment, addressing both readiness of existing resources, and readiness of processes that enable cross-domain communication and information exchange across disciplinary boundaries. Our initial assessment considers basic infrastructure components required to enable cross-domain interoperability in the geosciences. These components, and the evaluation metrics

  4. Component-Level Prognostics Health Management Framework for Passive Components - Advanced Reactor Technology Milestone: M2AT-15PN2301043

    Energy Technology Data Exchange (ETDEWEB)

    Ramuhalli, Pradeep; Roy, Surajit; Hirt, Evelyn H.; Prowant, Matthew S.; Pitman, Stan G.; Tucker, Joseph C.; Dib, Gerges; Pardini, Allan F.

    2015-06-19

    This report describes research results to date in support of the integration and demonstration of diagnostics technologies for prototypical advanced reactor passive components (to establish condition indices for monitoring) with model-based prognostics methods. Achieving this objective will necessitate addressing several of the research gaps and technical needs described in previous technical reports in this series.

  5. Retention of technical professionals

    OpenAIRE

    2012-01-01

    M.Ing. The loss of skills and knowledge of technical professionals experienced by many organizations in South Africa has serious implications on the competitiveness of these organizations in the local and international markets. Organizations should come to realize that they should find creative ways to retain critical skills and knowledge and ensure continuity in terms of succession management. Technical professionals play a crucial role in society. They are responsible for maintaining the...

  6. Understanding Socio Technical Modularity

    DEFF Research Database (Denmark)

    Thuesen, Christian Langhoff; Kudsk, Anders; Hvam, Lars

    2011-01-01

    dimension of modularity like irrational behaviors, cultural differences, learning processes, social organization and institutional influences on modularity. The paper addresses this gab offering a reinterpretation of the modularity concept from a socio-technical perspective in general and Actor Network...... Theory in particular. By formulating modularity from an ANT perspective covering social, material and process aspects, the modularity of a socio-technical system can be understood as an entanglement of product, process, organizational and institutional modularity. The theoretical framework is illustrated...

  7. A component architecture for the two-phase flows simulation system Neptune

    International Nuclear Information System (INIS)

    Bechaud, C.; Boucker, M.; Douce, A.; Grandotto, M.; Tajchman, M.

    2003-01-01

    Electricite de France (EdF) and the French atomic energy commission (Cea) have planed a large project to build a new set of software in nuclear reactors analysis. One of the main idea is to allow coupled calculations in which several scientific domains are involved. This paper presents the software architecture of the two-phase flows simulation Neptune project. Neptune should allow computations of two-phase flows in 3 dimensions under normal operating conditions as well as safety conditions. Three scales are identified: the local scale where there is only homogenization between the two phases, an intermediate scale where solid internal structures are homogenized with the fluid and the system scale where some parts of the geometry under study are considered point-wise or subject to one dimensional simplifications. The main properties of this architecture are as follow: -) coupling with scientific domains, and between different scales, -) re-using of quite all or parts of existing validated codes, -) components usable by the different scales, -) easy introducing of new physical modeling as well as new numerical methods, -) local, distributed and parallel computing. The Neptune architecture is based on the component concept with stable and well suited interface. In the case of a distributed application the components are managed through a Corba bus. The building of the components is organized in shell: a programming shell (Fortran or C++ routines), a managing shell (C++ language), an interpreted shell (Python language), a Corba shell and a global driving shell (C++ or Python). Neptune will use the facilities offered by the Salome project: pre and post processors and controls. A data model has been built to have a common access to the information exchanged between the components (meshes, fields, physical and technical information). This architecture has first been setup and tested on some simple but significant cases and is now currently in use to build the Neptune

  8. Frequency domain analysis of piping systems under short duration loading

    International Nuclear Information System (INIS)

    Sachs, K.; Sand, H.; Lockau, J.

    1981-01-01

    In piping analysis two procedures are used almost exclusively: the modal superposition method for relatively long input time histories (e.g., earthquake) and direct integration of the equations of motion for short input time histories. A third possibility, frequency domain analysis, has only rarely been applied to piping systems to date. This paper suggests the use of frequency domain analysis for specific piping problems for which only direct integration could be used in the past. Direct integration and frequency domain analysis are compared, and it is shown that the frequency domain method is less costly if more than four or five load cases are considered. In addition, this method offers technical advantages, such as more accurate representation of modal damping and greater insight into the structural behavior of the system. (orig.)

  9. Research regarding reverse engineering for aircraft components

    Directory of Open Access Journals (Sweden)

    Udroiu Razvan

    2017-01-01

    Full Text Available Reverse engineering is a useful technique used in manufacturing and design process of new components. In aerospace industry new components can be developed, based on existing components without technical Computer Aided Design (CAD data, in order to reduce the development cycle of new products. This paper proposes a methodology wherein the CAD model of turbine blade can be build using computer aided reverse engineering technique utilising a 5 axis Coordinate Measuring Machine (CMM. The proposed methodology uses a scanning strategy by features, followed by a design methodology for 3D modelling of complex shapes.

  10. Functional Domain Driven Design

    OpenAIRE

    Herrera Guzmán, Sergio

    2016-01-01

    Las tecnologías están en constante expansión y evolución, diseñando nuevas técnicas para cumplir con su fin. En el desarrollo de software, las herramientas y pautas para la elaboración de productos software constituyen una pieza en constante evolución, necesarias para la toma de decisiones sobre los proyectos a realizar. Uno de los arquetipos para el desarrollo de software es el denominado Domain Driven Design, donde es importante conocer ampliamente el negocio que se desea modelar en form...

  11. Socio-Technical Security Metrics (Dagstuhl Seminar 14491)

    NARCIS (Netherlands)

    Gollmann, Dieter; Herley, Cormac; Koenig, Vincent; Pieters, Wolter; Sasse, Martina Angela

    2015-01-01

    This report documents the program and the outcomes of Dagstuhl Seminar 14491 "Socio-Technical Security Metrics". In the domain of safety, metrics inform many decisions, from the height of new dikes to the design of nuclear plants. We can state, for example, that the dikes should be high enough to

  12. RNA polymerase II transcription is concentrated outside replication domains throughout S-phase

    NARCIS (Netherlands)

    Wansink, D. G.; Manders, E. E.; van der Kraan, I.; Aten, J. A.; van Driel, R.; de Jong, L.

    1994-01-01

    Transcription and replication are, like many other nuclear functions and components, concentrated in nuclear domains. Transcription domains and replication domains may play an important role in the coordination of gene expression and gene duplication in S-phase. We have investigated the spatial

  13. Technical Teachers and Technical Teacher Education - Research Results

    Directory of Open Access Journals (Sweden)

    D. Dobrovská

    2002-01-01

    Full Text Available Chartered engineers who are new teachers of technical subjects at various educational institutions receive technical teacher education in the accredited bachelor programme at the Czech Technical University in Prague. This paper presents the results of a recent survey in which engineers expressed their opinions on technical teacher education.

  14. Writing Globally: Teaching the Technical Writing Student To Prepare Documents for Translation.

    Science.gov (United States)

    Maylath, Bruce

    1997-01-01

    Argues that technical communication courses, particularly introductory courses in technical writing, must include a translation component if they are to prepare students for the kind of work they are now likely to encounter as technical communicators. Suggests the time is ripe for changing the curriculum so that students receive instruction in how…

  15. Summarization by domain ontology navigation

    DEFF Research Database (Denmark)

    Andreasen, Troels; Bulskov, Henrik

    2013-01-01

    of the subject. In between these two extremes, conceptual summaries encompass selected concepts derived using background knowledge. We address in this paper an approach where conceptual summaries are provided through a conceptualization as given by an ontology. The ontology guiding the summarization can...... be a simple taxonomy or a generative domain ontology. A domain ontology can be provided by a preanalysis of a domain corpus and can be used to condense improved summaries that better reflects the conceptualization of a given domain....

  16. The development of component-based information systems

    CERN Document Server

    Cesare, Sergio de; Macredie, Robert

    2015-01-01

    This work provides a comprehensive overview of research and practical issues relating to component-based development information systems (CBIS). Spanning the organizational, developmental, and technical aspects of the subject, the original research included here provides fresh insights into successful CBIS technology and application. Part I covers component-based development methodologies and system architectures. Part II analyzes different aspects of managing component-based development. Part III investigates component-based development versus commercial off-the-shelf products (COTS), includi

  17. Towards a Conceptual Design of a Cross-Domain Integrative Information System for the Geosciences

    Science.gov (United States)

    Zaslavsky, I.; Richard, S. M.; Valentine, D. W.; Malik, T.; Gupta, A.

    2013-12-01

    As geoscientists increasingly focus on studying processes that span multiple research domains, there is an increased need for cross-domain interoperability solutions that can scale to the entire geosciences, bridging information and knowledge systems, models, software tools, as well as connecting researchers and organization. Creating a community-driven cyberinfrastructure (CI) to address the grand challenges of integrative Earth science research and education is the focus of EarthCube, a new research initiative of the U.S. National Science Foundation. We are approaching EarthCube design as a complex socio-technical system of systems, in which communication between various domain subsystems, people and organizations enables more comprehensive, data-intensive research designs and knowledge sharing. In particular, we focus on integrating 'traditional' layered CI components - including information sources, catalogs, vocabularies, services, analysis and modeling tools - with CI components supporting scholarly communication, self-organization and social networking (e.g. research profiles, Q&A systems, annotations), in a manner that follows and enhances existing patterns of data, information and knowledge exchange within and across geoscience domains. We describe an initial architecture design focused on enabling the CI to (a) provide an environment for scientifically sound information and software discovery and reuse; (b) evolve by factoring in the impact of maturing movements like linked data, 'big data', and social collaborations, as well as experience from work on large information systems in other domains; (c) handle the ever increasing volume, complexity and diversity of geoscience information; (d) incorporate new information and analytical requirements, tools, and techniques, and emerging types of earth observations and models; (e) accommodate different ideas and approaches to research and data stewardship; (f) be responsive to the existing and anticipated needs

  18. Superphenix: technical and scientific achievements

    International Nuclear Information System (INIS)

    Guidez, Joel; Prele, Gerard

    2016-04-01

    In this book, the authors propose a synthesis of technical and scientific achievements related to the design, fabrication and eleven-year operation of Superphenix, the most powerful fast breeder reactor ever built and operated. They had the opportunity to use various and important archives maintained by the different involved institutions, actors and companies, such as the CEA with its MADONA database, AREVA and EDF. They address all the different fields: construction, chemistry, exploitation, handling, small and large components, materials, fuel manufacturing, environmental assessment, thermal hydraulics, the sodium-water reaction, sodium fires, the release of residual power, in-service inspection, and dismantling operations. Moreover, a chapter addresses design studies for Superphenix 2 and for the European Fast Reactor (EFR) which should be the successors of Superphenix

  19. XML for Domain Viewpoints

    CERN Document Server

    Van Lingen, F; Van der Stok, P D V; Willers, Ian Malcolm

    2001-01-01

    Within research institutions like CERN (European Organization for Nuclear Research) there are often disparate databases (different in format, type and structure) that users need to access in a domain-specific manner. Users may want to access a simple unit of information without having to understand detail of the underlying schema or they may want to access the same information from several different sources. It is neither desirable nor feasible to require users to have knowledge of these schemas. Instead it would be advantageous if a user could query these sources using his or her own domain models and abstractions of the data. This paper describes the basis of an XML (eXtended Markup Language) framework that provides this functionality and is currently being developed at CERN. The goal of the first prototype was to explore the possibilities of XML for data integration and model management. It shows how XML can be used to integrate data sources. The framework is not only applicable to CERN data sources but ot...

  20. On Probability Domains IV

    Science.gov (United States)

    Frič, Roman; Papčo, Martin

    2017-12-01

    Stressing a categorical approach, we continue our study of fuzzified domains of probability, in which classical random events are replaced by measurable fuzzy random events. In operational probability theory (S. Bugajski) classical random variables are replaced by statistical maps (generalized distribution maps induced by random variables) and in fuzzy probability theory (S. Gudder) the central role is played by observables (maps between probability domains). We show that to each of the two generalized probability theories there corresponds a suitable category and the two resulting categories are dually equivalent. Statistical maps and observables become morphisms. A statistical map can send a degenerated (pure) state to a non-degenerated one —a quantum phenomenon and, dually, an observable can map a crisp random event to a genuine fuzzy random event —a fuzzy phenomenon. The dual equivalence means that the operational probability theory and the fuzzy probability theory coincide and the resulting generalized probability theory has two dual aspects: quantum and fuzzy. We close with some notes on products and coproducts in the dual categories.

  1. Metaphors, domains and embodiment

    Directory of Open Access Journals (Sweden)

    M.E. Botha

    2005-07-01

    Full Text Available Investigations of metaphorical meaning constitution and meaning (in- variance have revealed the significance of semantic and semiotic domains and the contexts within which they function as basis for the grounding of metaphorical meaning. In this article some of the current views concerning the grounding of metaphorical meaning in experience and embodiment are explored. My provisional agreement with Lakoff, Johnson and others about the “conceptual” nature of metaphor rests on an important caveat, viz. that this bodily based conceptual structure which lies at the basis of linguistic articulations of metaphor, is grounded in a deeper ontic structure of the world and of human experience. It is the “metaphorical” (actually “analogical” ontological structure of this grounding that is of interest for the line of argumentation followed in this article. Because Johnson, Lakoff and other’s proposal to ground metaphorical meaning in embodiment and neural processes is open to being construed as subjectivist and materialist, I shall attempt to articulate the contours of an alternative theory of conceptual metaphor, meaning and embodiment which counteracts these possibilities. This theory grounds metaphorical meaning and meaning change in an ontological and anthropological framework which recognises the presence and conditioning functioning of radially ordered structures for reality. These categorisations in which humankind, human knowledge and reality participate, condition and constrain (ground analogical and metaphorical meaning transfer, cross-domain mappings, and blends in cognition and in language, provide the basis for the analogical concepts found in these disciplines.

  2. Expansion of protein domain repeats.

    Directory of Open Access Journals (Sweden)

    Asa K Björklund

    2006-08-01

    Full Text Available Many proteins, especially in eukaryotes, contain tandem repeats of several domains from the same family. These repeats have a variety of binding properties and are involved in protein-protein interactions as well as binding to other ligands such as DNA and RNA. The rapid expansion of protein domain repeats is assumed to have evolved through internal tandem duplications. However, the exact mechanisms behind these tandem duplications are not well-understood. Here, we have studied the evolution, function, protein structure, gene structure, and phylogenetic distribution of domain repeats. For this purpose we have assigned Pfam-A domain families to 24 proteomes with more sensitive domain assignments in the repeat regions. These assignments confirmed previous findings that eukaryotes, and in particular vertebrates, contain a much higher fraction of proteins with repeats compared with prokaryotes. The internal sequence similarity in each protein revealed that the domain repeats are often expanded through duplications of several domains at a time, while the duplication of one domain is less common. Many of the repeats appear to have been duplicated in the middle of the repeat region. This is in strong contrast to the evolution of other proteins that mainly works through additions of single domains at either terminus. Further, we found that some domain families show distinct duplication patterns, e.g., nebulin domains have mainly been expanded with a unit of seven domains at a time, while duplications of other domain families involve varying numbers of domains. Finally, no common mechanism for the expansion of all repeats could be detected. We found that the duplication patterns show no dependence on the size of the domains. Further, repeat expansion in some families can possibly be explained by shuffling of exons. However, exon shuffling could not have created all repeats.

  3. Methylation analysis of polysaccharides: Technical advice.

    Science.gov (United States)

    Sims, Ian M; Carnachan, Susan M; Bell, Tracey J; Hinkley, Simon F R

    2018-05-15

    Glycosyl linkage (methylation) analysis is used widely for the structural determination of oligo- and poly-saccharides. The procedure involves derivatisation of the individual component sugars of a polysaccharide to partially methylated alditol acetates which are analysed and quantified by gas chromatography-mass spectrometry. The linkage positions for each component sugar can be determined by correctly identifying the partially methylated alditol acetates. Although the methods are well established, there are many technical aspects to this procedure and both careful attention to detail and considerable experience are required to achieve a successful methylation analysis and to correctly interpret the data generated. The aim of this article is to provide the technical details and critical procedural steps necessary for a successful methylation analysis and to assist researchers (a) with interpreting data correctly and (b) in providing the comprehensive data required for reviewers to fully assess the work. Copyright © 2018 Elsevier Ltd. All rights reserved.

  4. An Improved Traffic Matrix Decomposition Method with Frequency-Domain Regularization

    OpenAIRE

    Wang, Zhe; Hu, Kai; Yin, Baolin

    2012-01-01

    We propose a novel network traffic matrix decomposition method named Stable Principal Component Pursuit with Frequency-Domain Regularization (SPCP-FDR), which improves the Stable Principal Component Pursuit (SPCP) method by using a frequency-domain noise regularization function. An experiment demonstrates the feasibility of this new decomposition method.

  5. First experience with the new .cern Top Level Domain

    Science.gov (United States)

    Alvarez, E.; Malo de Molina, M.; Salwerowicz, M.; Silva De Sousa, B.; Smith, T.; Wagner, A.

    2017-10-01

    In October 2015, CERN’s core website has been moved to a new address, http://home.cern, marking the launch of the brand new top-level domain .cern. In combination with a formal governance and registration policy, the IT infrastructure needed to be extended to accommodate the hosting of Web sites in this new top level domain. We will present the technical implementation in the framework of the CERN Web Services that allows to provide virtual hosting, a reverse proxy solution and that also includes the provisioning of SSL server certificates for secure communications.

  6. Fuzzy Bases of Fuzzy Domains

    Directory of Open Access Journals (Sweden)

    Sanping Rao

    2013-01-01

    Full Text Available This paper is an attempt to develop quantitative domain theory over frames. Firstly, we propose the notion of a fuzzy basis, and several equivalent characterizations of fuzzy bases are obtained. Furthermore, the concept of a fuzzy algebraic domain is introduced, and a relationship between fuzzy algebraic domains and fuzzy domains is discussed from the viewpoint of fuzzy basis. We finally give an application of fuzzy bases, where the image of a fuzzy domain can be preserved under some special kinds of fuzzy Galois connections.

  7. Decomposition of noise signals composed of many similar components

    International Nuclear Information System (INIS)

    Grabner, A.; Liewers, P.; Schumann, P.; Weiss, F.P.

    1977-05-01

    The interpretation of noise signals which are composed of many similar components from different noise sources is extremely difficult. By means of an experimental example the possibility of decomposition in the frequency and time domain is demonstrated. (author)

  8. Yucca Mountain Climate Technical Support Representative

    International Nuclear Information System (INIS)

    Sharpe, Saxon E

    2007-01-01

    The primary objective of Project Activity ORD-FY04-012, 'Yucca Mountain Climate Technical Support Representative', was to provide the Office of Civilian Radioactive Waste Management (OCRWM) with expertise on past, present, and future climate scenarios and to support the technical elements of the Yucca Mountain Project (YMP) climate program. The Climate Technical Support Representative was to explain, defend, and interpret the YMP climate program to the various audiences during Site Recommendation and License Application. This technical support representative was to support DOE management in the preparation and review of documents, and to participate in comment response for the Final Environmental Impact Statement, the Site Recommendation Hearings, the NRC Sufficiency Comments, and other forums as designated by DOE management. Because the activity was terminated 12 months early and experience a 27% reduction in budget, it was not possible to complete all components of the tasks as originally envisioned. Activities not completed include the qualification of climate datasets and the production of a qualified technical report. The following final report is an unqualified summary of the activities that were completed given the reduced time and funding

  9. Technical training: places available

    CERN Multimedia

    2013-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924)   Electronics design Next Session Duration Language Introduction to VHDL 21-Feb-13 to 22-Feb-13 2 days English Mechanical design Next Session Duration Language ANSYS - Introduction à ANSYS Mechanical APDL 04-Feb-13 to 07-Feb-13 4 days English Applications de la cotation fonctionnelle et du langage ISO 06-Feb-13 to 08-Feb-13 2 days 4 hours French CATIA V5 – Surfacique 14-Jan-13 to 15-Jan-13 2 days French Office software Next Session Duration Language ACCESS 2010 - niveau 2 : ECDL 06-Feb-13 to 07-Feb-13 2 days French Dreamweaver CS3 - Niveau 1 14-Jan-13 to 15-Jan-13 2 d...

  10. Technical training - Places available

    CERN Multimedia

    2012-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924)   Electronics design Next Session Duration Language Availability Certified LabVIEW Associate Developer (CLAD) 06-Dec-12 to 06-Dec-12 1 hour English One more place available Compatibilité électromagnetique (CEM): Applications 23-Nov-12 to 23-Nov-12 3.5 hours English 3 places available Compatibilité électromagnétique (CEM): Introduction 23-Nov-12 to 23-Nov-12 3 hours English 43 places available Effets des Radiations sur les composants et systèmes électroniques 11-Dec-12 to 12-Dec-12 1 day 4 hours French 9 places available LabVIEW for beginners ...

  11. Windows 10 Technical Preview

    OpenAIRE

    Jyväsjärvi, Teppo

    2015-01-01

    Tässä opinnäytetyössä tutustaan uuden kesällä 2015 virallisesti julkaistavan Windows 10 -käyttöjärjestelmän Technical Preview -kehitysversioon. Ensimmäinen Technical Preview -versio julkaistiin syksyllä 2014. Opinnäytetyössä tutustaan Windows 10:n uusin ominaisuuksiin ja tehdään vertailua aiemman Windows 8.1 -version kanssa. Työssä Windows 10 Technical Preview asennetaan virtuaalikoneelle, käydään läpi asennuksen eri vaiheet sekä suurimmat muutokset käyttöliittymässä ja sovelluksissa. Op...

  12. Technical training - places available

    CERN Multimedia

    2012-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924) HR Department »Electronics design Next Session Duration Language Availability Comprehensive VHDL for FPGA Design 08-Oct-12 to 12-Oct-12 5 days English 3 places available Foundations of Electromagnetism and Magnet Design (EMAG) 14-Nov-12 to 27-Nov-12 6 days English 20 places available Impacts de la suppression du plomb (RoHS) en électronique 26-Oct-12 to 26-Oct-12 8 hours French 15 places available Introduction to VHDL 10-Oct-12 to 11-Oct-12 2 days English 7 places available LabVIEW Real Time and FPGA 13-Nov-12 to 16-Nov-12 5 days French 5 places available »Mechanical design Next Se...

  13. Fuel Element Technical Manual

    Energy Technology Data Exchange (ETDEWEB)

    Burley, H.H. [ed.

    1956-08-01

    It is the purpose of the Fuel Element Technical Manual to Provide a single document describing the fabrication processes used in the manufacture of the fuel element as well as the technical bases for these processes. The manual will be instrumental in the indoctrination of personnel new to the field and will provide a single data reference for all personnel involved in the design or manufacture of the fuel element. The material contained in this manual was assembled by members of the Engineering Department and the Manufacturing Department at the Hanford Atomic Products Operation between the dates October, 1955 and June, 1956. Arrangement of the manual. The manual is divided into six parts: Part I--introduction; Part II--technical bases; Part III--process; Part IV--plant and equipment; Part V--process control and improvement; and VI--safety.

  14. The framing of scientific domains

    DEFF Research Database (Denmark)

    Dam Christensen, Hans

    2014-01-01

    Purpose: By using the UNISIST models this article argues for the necessity of domain analysis in order to qualify scientific information seeking. The models better understanding of communication processes in a scientific domain and embraces the point that domains are always both unstable over time...... and changeable according to the specific perspective. This understanding is even more important today as numerous digitally generated information tools as well as collaborative and interdisciplinary research are blurring the domain borders. Nevertheless, researchers navigate “intuitively” in “their” specific...... as according to the agents that are charting them. As such, power in a Foucauldian sense is unavoidable in outlining a domain. Originality/value 1. The UNISIST models are applied to the domain of art history; and 2. the article discusses the instability of a scientific domain as well as, at the same time...

  15. Feature-level domain adaptation

    DEFF Research Database (Denmark)

    Kouw, Wouter M.; Van Der Maaten, Laurens J P; Krijthe, Jesse H.

    2016-01-01

    Domain adaptation is the supervised learning setting in which the training and test data are sampled from different distributions: training data is sampled from a source domain, whilst test data is sampled from a target domain. This paper proposes and studies an approach, called feature......-level domain adaptation (flda), that models the dependence between the two domains by means of a feature-level transfer model that is trained to describe the transfer from source to target domain. Subsequently, we train a domain-adapted classifier by minimizing the expected loss under the resulting transfer...... model. For linear classifiers and a large family of loss functions and transfer models, this expected loss can be computed or approximated analytically, and minimized efficiently. Our empirical evaluation of flda focuses on problems comprising binary and count data in which the transfer can be naturally...

  16. Domain architecture conservation in orthologs

    Science.gov (United States)

    2011-01-01

    Background As orthologous proteins are expected to retain function more often than other homologs, they are often used for functional annotation transfer between species. However, ortholog identification methods do not take into account changes in domain architecture, which are likely to modify a protein's function. By domain architecture we refer to the sequential arrangement of domains along a protein sequence. To assess the level of domain architecture conservation among orthologs, we carried out a large-scale study of such events between human and 40 other species spanning the entire evolutionary range. We designed a score to measure domain architecture similarity and used it to analyze differences in domain architecture conservation between orthologs and paralogs relative to the conservation of primary sequence. We also statistically characterized the extents of different types of domain swapping events across pairs of orthologs and paralogs. Results The analysis shows that orthologs exhibit greater domain architecture conservation than paralogous homologs, even when differences in average sequence divergence are compensated for, for homologs that have diverged beyond a certain threshold. We interpret this as an indication of a stronger selective pressure on orthologs than paralogs to retain the domain architecture required for the proteins to perform a specific function. In general, orthologs as well as the closest paralogous homologs have very similar domain architectures, even at large evolutionary separation. The most common domain architecture changes observed in both ortholog and paralog pairs involved insertion/deletion of new domains, while domain shuffling and segment duplication/deletion were very infrequent. Conclusions On the whole, our results support the hypothesis that function conservation between orthologs demands higher domain architecture conservation than other types of homologs, relative to primary sequence conservation. This supports the

  17. Technical memory 2007

    International Nuclear Information System (INIS)

    2009-01-01

    The technical memory 2007 of the Nuclear Regulatory Authority (ARN) of the Argentine Republic, compiles the papers published in the subject on radiation protection and nuclear safety, and presented in journals, technical reports, congress or meetings of these specialities by personnel of the mentioned institution during 2007. In this edition the documents are presented on: environmental protection; transport of radioactive materials; regulations; research reactors and nuclear power plants; biological radiation effects; therapeutic uses of ionizing radiation and radioprotection of patients; internal dosimetry; physical dosimetry; knowledge management; radioactive waste management [es

  18. Transformation of technical infrastructure

    DEFF Research Database (Denmark)

    Nielsen, Susanne Balslev

    , the evolution of large technological systems and theories about organisational and technological transformationprocesses. The empirical work consist of three analysis at three different levels: socio-technical descriptions of each sector, an envestigation of one municipality and envestigations of one workshop......The scope of the project is to investigate the possibillities of - and the barriers for a transformation of technical infrastructure conserning energy, water and waste. It focus on urban ecology as a transformation strategy. The theoretical background of the project is theories about infrastructure...

  19. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    You are running Vista on your new PC – or are planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual sessions of this course will take place on 12 December 2008 and 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at mailto:Technical.Training@cern.ch

  20. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2009-01-01

    Are you running Vista on your new PC – or are you planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual session of this course will take place on 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at mailto:Technical.Training@cern.ch

  1. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    You are running Vista on your new PC – or are planning to install it? The Technical Training service is organizing a half-day training on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced using Windows XP. The next bilingual sessions of this course will take place on December 12, 2008 and January 30, 2009. Register using our catalogue : http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at Technical.Training@cern.ch

  2. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    Are you running Vista on your new PC – or are you planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual sessions of this course will take place on 12 December 2008 and 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at mailto:Technical.Training@cern.ch

  3. CERN Technical Training : Vista !

    CERN Multimedia

    HR Department

    2008-01-01

    Are you running Vista on your new PC – or are planning to install it? The Technical Training service is organizing a half-day training course on the new features of the VISTA operating system. This course introduces the new interfaces and presents the new functionalities for people who are experienced in the use of Windows XP. The next bilingual sessions of this course will take place on 12 December 2008 and 30 January 2009. Register using our catalogue: http://cta.cern.ch/cta2/f?p=110:9 or contact us with your questions/comments at Technical.Training@cern.ch

  4. Mitigating component performance variation

    Science.gov (United States)

    Gara, Alan G.; Sylvester, Steve S.; Eastep, Jonathan M.; Nagappan, Ramkumar; Cantalupo, Christopher M.

    2018-01-09

    Apparatus and methods may provide for characterizing a plurality of similar components of a distributed computing system based on a maximum safe operation level associated with each component and storing characterization data in a database and allocating non-uniform power to each similar component based at least in part on the characterization data in the database to substantially equalize performance of the components.

  5. Variability and component composition

    NARCIS (Netherlands)

    T. van der Storm (Tijs)

    2004-01-01

    textabstractIn component-based product populations, feature models have to be described at the component level to be able to benefit from a product family approach. As a consequence, composition of components becomes very complex. We describe how component-level variability can be managed in the

  6. Domain Engineering - A Software Engineering discipline in Need of Research

    DEFF Research Database (Denmark)

    Bjørner, Dines

    2000-01-01

    , and these again seem more stable than software designs. Thus, almost like the universal laws of physics, it pays off to first develop theories of domains. But domain engineering, as in fact also requirements engineering, really is in need of thoroughly researched development principles, techniques and tools....... The aim of this paper is to advocate: that researchers study these development method components, and that universities focus their education on basing well-nigh any course on the use of formal techniques: Specification and verification, and that software engineers take heed: Start applying formal......Before software can be developed its requirements must be stated. Before requirements can be expressed the application domain must be understood. In this paper we outline some of the basic facets of domain engineering. Domains seem, it is our experience, far more stable than computing requirements...

  7. Contribution of domain wall networks to the CMB power spectrum

    Directory of Open Access Journals (Sweden)

    A. Lazanu

    2015-07-01

    Full Text Available We use three domain wall simulations from the radiation era to the late-time dark energy domination era based on the PRS algorithm to calculate the energy–momentum tensor components of domain wall networks in an expanding universe. Unequal time correlators in the radiation, matter and cosmological constant epochs are calculated using the scaling regime of each of the simulations. The CMB power spectrum of a network of domain walls is determined. The first ever quantitative constraint for the domain wall surface tension is obtained using a Markov chain Monte Carlo method; an energy scale of domain walls of 0.93 MeV, which is close but below the Zel'dovich bound, is determined.

  8. Domain Engineering, A Software Engineering Discipline in Need of Research

    DEFF Research Database (Denmark)

    Bjørner, Dines

    2000-01-01

    Before software can be developed its requirements must be stated. Before requirements can be expressed the application domain must be understood. In this paper we outline some of the basic facets of domain engineering. Domains seem, it is our experience, far more stable than computing requirements......, and these again seem more stable than software designs. Thus, almost like the universal laws of physics, it pays off to first develop theories of domains. But domain engineering, as in fact also requirements engineering, really is in need of thoroughly researched development principles, techniques and tools....... The aim of this paper is to advocate: that researchers study these development method components, and that universities focus their education on basing well-nigh any course on the use of formal techniques: Specification and verification, and that software engineers take heed: Start applying formal...

  9. Magnetic domains in Ni-Mn-Ga martensitic thin films

    International Nuclear Information System (INIS)

    Chernenko, V A; Anton, R Lopez; Kohl, M; Ohtsuka, M; Orue, I; Barandiaran, J M

    2005-01-01

    A series of martensitic Ni 52 Mn 24 Ga 24 thin films deposited on alumina ceramic substrates has been prepared by using RF(radio-frequency) magnetron sputtering. The film thickness, d, varies from 0.1 to 5.0m. Magnetic domain patterns have been imaged by the MFM (magnetic force microscopy) technique. A maze domain structure is found for all studied films. MFM shows a large out-of-plane magnetization component and a rather uniform domain width for each film thickness. The domain width, δ, depends on the film thickness as δ∝√d in the whole studied range of film thickness. This dependence is the expected one for magnetic anisotropy and magnetostatic contributions in a perpendicular magnetic domain configuration. The proportionality coefficient is also consistent with the values of saturation magnetization and magnetic anisotropy determined in the samples

  10. Protein domain organisation: adding order

    Directory of Open Access Journals (Sweden)

    Kummerfeld Sarah K

    2009-01-01

    Full Text Available Abstract Background Domains are the building blocks of proteins. During evolution, they have been duplicated, fused and recombined, to produce proteins with novel structures and functions. Structural and genome-scale studies have shown that pairs or groups of domains observed together in a protein are almost always found in only one N to C terminal order and are the result of a single recombination event that has been propagated by duplication of the multi-domain unit. Previous studies of domain organisation have used graph theory to represent the co-occurrence of domains within proteins. We build on this approach by adding directionality to the graphs and connecting nodes based on their relative order in the protein. Most of the time, the linear order of domains is conserved. However, using the directed graph representation we have identified non-linear features of domain organization that are over-represented in genomes. Recognising these patterns and unravelling how they have arisen may allow us to understand the functional relationships between domains and understand how the protein repertoire has evolved. Results We identify groups of domains that are not linearly conserved, but instead have been shuffled during evolution so that they occur in multiple different orders. We consider 192 genomes across all three kingdoms of life and use domain and protein annotation to understand their functional significance. To identify these features and assess their statistical significance, we represent the linear order of domains in proteins as a directed graph and apply graph theoretical methods. We describe two higher-order patterns of domain organisation: clusters and bi-directionally associated domain pairs and explore their functional importance and phylogenetic conservation. Conclusion Taking into account the order of domains, we have derived a novel picture of global protein organization. We found that all genomes have a higher than expected

  11. The Garrison Domain: Civil Military Relations in the Cyberspace Domain

    Science.gov (United States)

    2015-04-01

    governance, commerce , communications, and entertainment. The reliance on cyberspace is so predominant it seems unacceptable to not be part of the domain...Almost every type of person and organization on this planet arguably touches the cyberspace domain, directly or indirectly. Because this domain is...Department of Justice (DOJ) has also begun using cyberspace to gather information intelligence. Flying small civilian aircraft with electronic boxes to

  12. Prediction Reweighting for Domain Adaptation.

    Science.gov (United States)

    Shuang Li; Shiji Song; Gao Huang

    2017-07-01

    There are plenty of classification methods that perform well when training and testing data are drawn from the same distribution. However, in real applications, this condition may be violated, which causes degradation of classification accuracy. Domain adaptation is an effective approach to address this problem. In this paper, we propose a general domain adaptation framework from the perspective of prediction reweighting, from which a novel approach is derived. Different from the major domain adaptation methods, our idea is to reweight predictions of the training classifier on testing data according to their signed distance to the domain separator, which is a classifier that distinguishes training data (from source domain) and testing data (from target domain). We then propagate the labels of target instances with larger weights to ones with smaller weights by introducing a manifold regularization method. It can be proved that our reweighting scheme effectively brings the source and target domains closer to each other in an appropriate sense, such that classification in target domain becomes easier. The proposed method can be implemented efficiently by a simple two-stage algorithm, and the target classifier has a closed-form solution. The effectiveness of our approach is verified by the experiments on artificial datasets and two standard benchmarks, a visual object recognition task and a cross-domain sentiment analysis of text. Experimental results demonstrate that our method is competitive with the state-of-the-art domain adaptation algorithms.

  13. Preliminary Work Domain Analysis for Human Extravehicular Activity

    Science.gov (United States)

    McGuire, Kerry; Miller, Matthew; Feigh, Karen

    2015-01-01

    A work domain analysis (WDA) of human extravehicular activity (EVA) is presented in this study. A formative methodology such as Cognitive Work Analysis (CWA) offers a new perspective to the knowledge gained from the past 50 years of living and working in space for the development of future EVA support systems. EVA is a vital component of human spaceflight and provides a case study example of applying a work domain analysis (WDA) to a complex sociotechnical system. The WDA presented here illustrates how the physical characteristics of the environment, hardware, and life support systems of the domain guide the potential avenues and functional needs of future EVA decision support system development.

  14. Control of Domain Wall Polarity by Current Pulses

    Science.gov (United States)

    Vanhaverbeke, A.; Bischof, A.; Allenspach, R.

    2008-09-01

    Direct observation of current-induced propagation of purely transverse magnetic domain walls with spin-polarized scanning electron microscopy is reported in Fe30Ni70 nanowires. After propagation, the domain walls keep their transverse nature but switch polarity in some cases. For uniform Ni70Fe30 wires, the effect is random and illustrates domain-wall propagation above the Walker threshold. In the case of Ni70Fe30/Fe wires, the transverse magnetization component in the wall is entirely determined by the polarity of the current pulse, an effect that is not reconciled by present theories even when taking into account the nonuniform Oersted field generated by the current.

  15. Importance of the Alternative Five and Trait Emotional Intelligence for Agentic and Communal Domains of Satisfaction

    Directory of Open Access Journals (Sweden)

    Andreja Avsec

    2011-12-01

    Full Text Available Many studies supported the importance of trait emotional intelligence (EI for subjective well-being but specific domains of life-satisfaction were rarely of interest. Our study investigated whether emotional intelligence is more important for interpersonal or communal-related domains (e.g. satisfaction with friends, intimate partners than for agentic domains of satisfaction (e.g. satisfaction with finances, work. Due to the problematic differential validity of trait EI from personality, the relationship between trait EI and domains of satisfaction was controlled for by personality. Slovene students and young adults (N=442 completed the Emotional Skills and Competence Questionnaire and the Zuckerman-Kuhlman Personality Questionnaire, and rated their satisfaction with 12 aspects of life. Principal component analysis of these domains revealed three components, explaining 62% of total variance. The communal domains included self-reported satisfaction with popularity, respect, influence on others, family relationships, and intimate relationship. The agentic domains included satisfaction with professional carrier, financial situation, academic education, and achieved goals. The physical domains component was comprised of satisfaction with appearance, fitness, and health. After accounting for personality, trait EI explained 16% of variance in communal domain and 10% of variance in agentic domain, thus suggesting greater importance of trait EI for interpersonal domains. However, trait EI seems to play an important role for satisfaction in the agentic domains also, as successful management of our emotions can help us reach our goals and thus be more satisfied.

  16. Technical Writing in Hydrogeology.

    Science.gov (United States)

    Tinker, John R., Jr.

    1986-01-01

    A project for Writing Across the Curriculum at the University of Wisconsin-Eau Claire is described as a method to relate the process of writing to the process of learning hydrology. The project focuses on an actual groundwater contamination case and is designed to improve the technical writing skills of students. (JN)

  17. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: LabVIEW Real-Time (F) : 7 - 9.6.2005 (3 jours) LabVIEW Migration 6 to 7: 14.6.2005 (1 day) IT3T/1 - Read your mail and more with Outlook 2003 : 14.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/2 - Creating, managing and using distribution lists with Simba2 : 16.6.2005 (IT Technical Training Tutorial, free of charge) FrontPage 2003 - niveau 2 : 16 & 17.6.2005 (2 jours) Utilisation de fichiers PDF avec ACROBAT 6.0 : 20.6.2005 (1journée) Introduction to ANSYS: 21 - 24.6.2005 (4 days) IT3T/3 - Working remotely with Windows XP : 28.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/4 - Editing Websites with Frontpage 2003 : 30.6.2005 (IT Technical Training Tutorial, free of charge) WORD 2003 (Short Course I) - HowTo... Work with repetitive tasks /AutoText, AutoFormat, AutoC...

  18. Technical objectives of inspection

    International Nuclear Information System (INIS)

    Sorenson, R.J.; Stewart, K.B.; Schneider, R.A.

    1976-01-01

    The various technical objectives of inspection are discussed in a very general manner. The discussion includes how the inspection function is related to the assumed threat, the various degrees of assurance and reliance on criteria, and the hierarchy of assurance which is obtained from the various types or levels of inspection

  19. Technical basis of safeguards

    International Nuclear Information System (INIS)

    Buechler, C.

    1975-01-01

    Definition of nuclear materials control. Materials accountancy and physical control as technical possibilities. Legal possibilities and levels of responsibility: material holders, national and international authority. Detection vs. prevention. Physical security and containment surveillance. Accountancy: materials balance concept. Materials measurement: inventory taking, flow determination. IAEA safeguards; verification of operator's statement. (HP) [de

  20. ITER EDA technical activities

    International Nuclear Information System (INIS)

    Aymar, R.

    1998-01-01

    Six years of technical work under the ITER EDA Agreement have resulted in a design which constitutes a complete description of the ITER device and of its auxiliary systems and facilities. The ITER Council commented that the Final Design Report provides the first comprehensive design of a fusion reactor based on well established physics and technology

  1. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: LabVIEW Migration 6 to 7: 14.6.2005 (1 day) IT3T/1 - Read your mail and more with Outlook 2003 : 14.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/2 - Creating, managing and using distribution lists with Simba2 : 16.6.2005 (IT Technical Training Tutorial, free of charge) FrontPage 2003 - niveau 2 : 16 & 17.6.2005 (2 jours) size="2">(1journée) Hands-on Introduction to Python Programming: 28 - 30.6.2005 (3 days) Introduction to ANSYS: 21 - 24.6.2005 (4 days) IT3T/3 - Working remotely with Windows XP: 28.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/4 - Editing Websites with Frontpage 2003: 30.6.2005 (IT Technical Training Tutorial, free of charge) LabVIEW base 1 : 4 - 6.7.2005 (3 jours) LabVIEW Basics 2: AutoCorrect, Find/Replace) : 4.7.2005 (afternoon) WORD 2003 (Shor...

  2. Final technical report

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    This project entails research with the goal to extend laser cutting of steel based metals to thickness above 20 mm and laser powers in the 10 kW range, with adequate accuracy and economically viable cutting speeds. The technical approach is to develop mirror based cutting heads with truly coaxial...

  3. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    John Ross

    2003-04-30

    The Final Technical Report summarizes research accomplishments and Publications in the period of 5/1/99 to 4/30/03 done on the grant. Extensive progress was made in the period covered by this report in the areas of chemical kinetics of non-linear systems; spatial structures, reaction - diffusion systems, and thermodynamic and stochastic theory of electrochemical and general systems.

  4. MCFire model technical description

    Science.gov (United States)

    David R. Conklin; James M. Lenihan; Dominique Bachelet; Ronald P. Neilson; John B. Kim

    2016-01-01

    MCFire is a computer program that simulates the occurrence and effects of wildfire on natural vegetation, as a submodel within the MC1 dynamic global vegetation model. This report is a technical description of the algorithms and parameter values used in MCFire, intended to encapsulate its design and features a higher level that is more conceptual than the level...

  5. Final Technical Report

    International Development Research Centre (IDRC) Digital Library (Canada)

    Tommy Ngai

    2014-03-31

    Mar 31, 2014 ... capacity building activities) to upgrade the technical and management capacities of governments ..... Elements of evaluation are required throughout the chain of activities in order to undertake a ...... Department of Water Supply and Sewerage Pokhara, Pokhara Engineering College, Choice Nepal, and.

  6. PISA 2009 Technical Report

    Science.gov (United States)

    OECD Publishing (NJ1), 2012

    2012-01-01

    The "PISA 2009 Technical Report" describes the methodology underlying the PISA 2009 survey. It examines additional features related to the implementation of the project at a level of detail that allows researchers to understand and replicate its analyses. The reader will find a wealth of information on the test and sample design,…

  7. PISA 2012 Technical Report

    Science.gov (United States)

    OECD Publishing, 2014

    2014-01-01

    The "PISA 2012 Technical Report" describes the methodology underlying the PISA 2012 survey, which tested 15-year-olds' competencies in mathematics, reading and science and, in some countries, problem solving and financial literacy. It examines the design and implementation of the project at a level of detail that allows researchers to…

  8. Materials Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-08-01

    Roadmap identifying the efforts of the Materials Technical Team (MTT) to focus primarily on reducing the mass of structural systems such as the body and chassis in light-duty vehicles (including passenger cars and light trucks) which enables improved vehicle efficiency regardless of the vehicle size or propulsion system employed.

  9. Technical memory 1999

    International Nuclear Information System (INIS)

    2000-01-01

    The technical memory 1999 of the Nuclear Regulatory Authority (NRA) of the Argentine Republic, compile the papers published in the subject on radiation protection and nuclear safety, safeguards and physical protection, and presented in congress or meetings of these specialities by personnel of the mentioned institution during 1999

  10. Component-Based Approach in Learning Management System Development

    Science.gov (United States)

    Zaitseva, Larisa; Bule, Jekaterina; Makarov, Sergey

    2013-01-01

    The paper describes component-based approach (CBA) for learning management system development. Learning object as components of e-learning courses and their metadata is considered. The architecture of learning management system based on CBA being developed in Riga Technical University, namely its architecture, elements and possibilities are…

  11. Fourier Domain Sensing

    Science.gov (United States)

    Feldkhun, Daniel (Inventor); Wagner, Kelvin H. (Inventor)

    2013-01-01

    Methods and systems are disclosed of sensing an object. A first radiation is spatially modulated to generate a structured second radiation. The object is illuminated with the structured second radiation such that the object produces a third radiation in response. Apart from any spatially dependent delay, a time variation of the third radiation is spatially independent. With a single-element detector, a portion of the third radiation is detected from locations on the object simultaneously. At least one characteristic of a sinusoidal spatial Fourier-transform component of the object is estimated from a time-varying signal from the detected portion of the third radiation.

  12. Mapping the Moral Domain

    Science.gov (United States)

    Graham, Jesse; Nosek, Brian A.; Haidt, Jonathan; Iyer, Ravi; Koleva, Spassena; Ditto, Peter H.

    2010-01-01

    The moral domain is broader than the empathy and justice concerns assessed by existing measures of moral competence, and it is not just a subset of the values assessed by value inventories. To fill the need for reliable and theoretically-grounded measurement of the full range of moral concerns, we developed the Moral Foundations Questionnaire (MFQ) based on a theoretical model of five universally available (but variably developed) sets of moral intuitions: Harm/care, Fairness/reciprocity, Ingroup/loyalty, Authority/respect, and Purity/sanctity. We present evidence for the internal and external validity of the scale and the model, and in doing so present new findings about morality: 1. Comparative model fitting of confirmatory factor analyses provides empirical justification for a five-factor structure of moral concerns. 2. Convergent/discriminant validity evidence suggests that moral concerns predict personality features and social group attitudes not previously considered morally relevant. 3. We establish pragmatic validity of the measure in providing new knowledge and research opportunities concerning demographic and cultural differences in moral intuitions. These analyses provide evidence for the usefulness of Moral Foundations Theory in simultaneously increasing the scope and sharpening the resolution of psychological views of morality. PMID:21244182

  13. LCA profiles for building components:

    DEFF Research Database (Denmark)

    Marsh, Rob

    2016-01-01

    , a new approach explores how environmental information on building components can be simplified for strategic use early in the design process in a Danish context. In this paper, life cycle assessments (LCAs) are undertaken for several hundred typical external wall solutions, based on relevant standards....... A full bivariate linear regression analysis is performed, showing statistically significant correlations with strong direct relationships between environmental impact categories. A simplified LCA profile consisting of total primary energy, global warming potential and acidification potential is developed....... This simplified LCA profile presents environmental data in a more understandable way, creating a strategic overview that can be easily used by non-technical clients and construction professionals in the early design stages. This has a scientific and statistical validity generated by environmental assessment...

  14. Technical Evaluation Report

    National Research Council Canada - National Science Library

    Werkhoven, Peter

    2007-01-01

    ...). Increased computer power at low cost, wireless networks, miniaturization of sensor and computer components, and better visual, auditory and tactile display systems are contributing to the maturation...

  15. Technical Evaluation Report

    National Research Council Canada - National Science Library

    Werkhoven, Peter

    2006-01-01

    ...). Increased computer power at low cost, wireless networks, miniaturizations of sensor and computer components, and better visual, auditory and tactile display systems are contributing to the maturation...

  16. Ligand binding by PDZ domains

    DEFF Research Database (Denmark)

    Chi, Celestine N.; Bach, Anders; Strømgaard, Kristian

    2012-01-01

    The postsynaptic density protein-95/disks large/zonula occludens-1 (PDZ) protein domain family is one of the most common protein-protein interaction modules in mammalian cells, with paralogs present in several hundred human proteins. PDZ domains are found in most cell types, but neuronal proteins...... as pathological conditions have been reviewed recently. In this review, we focus on the molecular details of how PDZ domains bind their protein ligands and their potential as drug targets in this context....

  17. The BRCT domain is a phospho-protein binding domain.

    Science.gov (United States)

    Yu, Xiaochun; Chini, Claudia Christiano Silva; He, Miao; Mer, Georges; Chen, Junjie

    2003-10-24

    The carboxyl-terminal domain (BRCT) of the Breast Cancer Gene 1 (BRCA1) protein is an evolutionarily conserved module that exists in a large number of proteins from prokaryotes to eukaryotes. Although most BRCT domain-containing proteins participate in DNA-damage checkpoint or DNA-repair pathways, or both, the function of the BRCT domain is not fully understood. We show that the BRCA1 BRCT domain directly interacts with phosphorylated BRCA1-Associated Carboxyl-terminal Helicase (BACH1). This specific interaction between BRCA1 and phosphorylated BACH1 is cell cycle regulated and is required for DNA damage-induced checkpoint control during the transition from G2 to M phase of the cell cycle. Further, we show that two other BRCT domains interact with their respective physiological partners in a phosphorylation-dependent manner. Thirteen additional BRCT domains also preferentially bind phospho-peptides rather than nonphosphorylated control peptides. These data imply that the BRCT domain is a phospho-protein binding domain involved in cell cycle control.

  18. Technical and Technological Skills Assessment in Laparoscopic Surgery

    OpenAIRE

    Sarker, Sudip K.; Chang, Avril; Vincent, Charles

    2006-01-01

    Objectives: Surgical appraisal and revalidation are key components of good surgical practice and training. Assessing technical skills in a structured manner is still not widely used. Laparoscopic surgery also requires the surgeon to be competent in technological aspects of the operation. Methods: Checklists for generic, specific technical, and technological skills for laparoscopic cholecystectomies were constructed. Two surgeons with >12 years postgraduate surgical experience assessed each op...

  19. Markets, Availability, Notice, and Technical Performance of Terahertz Systems: Historic Development, Present, and Trends

    Science.gov (United States)

    Hochrein, Thomas

    2015-03-01

    Although a lot of work has already been done under the older terms "far infrared" or "sub-millimeter waves", the term "terahertz" stands for a novel technique offering many potential applications. The latter term also represents a new generation of systems with the opportunity for coherent, time-resolved detection. In addition to the well-known technical opportunities, an historical examination of Internet usage, as well as the number of publications and patent applications, confirms ongoing interest in this technique. These activities' annual growth rate is between 9 % and 21 %. The geographical distribution shows the center of terahertz activities. A shift from the scientific to more application-oriented research can be observed. We present a survey among worldwide terahertz suppliers with special focus on the European region and the use of terahertz systems in the field of measurement and analytical applications. This reveals the current state of terahertz systems' commercial and geographical availability as well as their costs, target markets, and technical performance. Component cost distribution using the example of an optical pulsed time-domain terahertz system gives an impression of the prevailing cost structure. The predication regarding prospective market development, decreasing system costs and higher availability shows a convenient situation for potential users and interested customers. The causes are primarily increased competition and larger quantities in the future.

  20. A Formal Approach to Domain-Oriented Software Design Environments

    Science.gov (United States)

    Lowry, Michael; Philpot, Andrew; Pressburger, Thomas; Underwood, Ian; Lum, Henry, Jr. (Technical Monitor)

    1994-01-01

    This paper describes a formal approach to domain-oriented software design environments, based on declarative domain theories, formal specifications, and deductive program synthesis. A declarative domain theory defines the semantics of a domain-oriented specification language and its relationship to implementation-level subroutines. Formal specification development and reuse is made accessible to end-users through an intuitive graphical interface that guides them in creating diagrams denoting formal specifications. The diagrams also serve to document the specifications. Deductive program synthesis ensures that end-user specifications are correctly implemented. AMPHION has been applied to the domain of solar system kinematics through the development of a declarative domain theory, which includes an axiomatization of JPL's SPICELIB subroutine library. Testing over six months with planetary scientists indicates that AMPHION's interactive specification acquisition paradigm enables users to develop, modify, and reuse specifications at least an order of magnitude more rapidly than manual program development. Furthermore, AMPHION synthesizes one to two page programs consisting of calls to SPICELIB subroutines from these specifications in just a few minutes. Test results obtained by metering AMPHION's deductive program synthesis component are examined. AMPHION has been installed at JPL and is currently undergoing further refinement in preparation for distribution to hundreds of SPICELIB users worldwide. Current work to support end-user customization of AMPHION's specification acquisition subsystem is briefly discussed, as well as future work to enable domain-expert creation of new AMPHION applications through development of suitable domain theories.

  1. Reusable Component Services

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Reusable Component Services (RCS) is a super-catalog of components, services, solutions and technologies that facilitates search, discovery and collaboration in...

  2. Software component quality evaluation

    Science.gov (United States)

    Clough, A. J.

    1991-01-01

    The paper describes a software inspection process that can be used to evaluate the quality of software components. Quality criteria, process application, independent testing of the process and proposed associated tool support are covered. Early results indicate that this technique is well suited for assessing software component quality in a standardized fashion. With automated machine assistance to facilitate both the evaluation and selection of software components, such a technique should promote effective reuse of software components.

  3. Bioethics for Technical Experts

    Science.gov (United States)

    Asano, Shigetaka

    Along with rapidly expanding applications of life science and technology, technical experts have been implicated more and more often with ethical, social, and legal problems than before. It should be noted that in this background there are scientific and social uncertainty elements which are inevitable during the progress of life science in addition to the historically-established social unreliability to scientists and engineers. In order to solve these problems, therefore, we should establish the social governance with ‘relief’ and ‘reliance’ which enables for both citizens and engineers to share the awareness of the issues, to design social orders and criterions based on hypothetical sense of values for bioethics, to carry out practical use management of each subject carefully, and to improve the sense of values from hypothetical to universal. Concerning these measures, the technical experts can learn many things from the present performance in the medical field.

  4. Sources of technical assistance

    International Nuclear Information System (INIS)

    Laue, H.J.

    1977-01-01

    This paper shows examples of technical assistance programmes within bilateral cooperation agreements between the Federal Republic of Germany and a number of developing countries of very different characteristics and summarizes the possibilities of technical assistance granted by international organizations, such as IAEA, UNDP, etc. A basic requirement for a successful transfer of technology is a high knowledge level of the indigenous scientists and engineers. Therefore, programmes for training and education and for information exchange are presented. Based on these, the means and methods of planning, performance and quality assurance are explained by practical examples and are related to the progress achieved in the use of nuclear energy and in establishing a national industry in the developing countries. (orig.) [de

  5. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: The Joint PVSS JCOP Framework: 14 - 18.6.2004 (5 days) EXCEL 2003 - niveau 2 : 17 & 18.6.2004 (2 jours) MAGNE-04 : Magnétisme pour l'électrotechnique : 6 au 8.7.2004 (3 jours) Technical Training Monique Duval - Tel.74924 technical.training@cern.ch

  6. Independent technical review, handbook

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    Purpose Provide an independent engineering review of the major projects being funded by the Department of Energy, Office of Environmental Restoration and Waste Management. The independent engineering review will address questions of whether the engineering practice is sufficiently developed to a point where a major project can be executed without significant technical problems. The independent review will focus on questions related to: (1) Adequacy of development of the technical base of understanding; (2) Status of development and availability of technology among the various alternatives; (3) Status and availability of the industrial infrastructure to support project design, equipment fabrication, facility construction, and process and program/project operation; (4) Adequacy of the design effort to provide a sound foundation to support execution of project; (5) Ability of the organization to fully integrate the system, and direct, manage, and control the execution of a complex major project.

  7. Independent technical review, handbook

    International Nuclear Information System (INIS)

    1994-02-01

    Purpose Provide an independent engineering review of the major projects being funded by the Department of Energy, Office of Environmental Restoration and Waste Management. The independent engineering review will address questions of whether the engineering practice is sufficiently developed to a point where a major project can be executed without significant technical problems. The independent review will focus on questions related to: (1) Adequacy of development of the technical base of understanding; (2) Status of development and availability of technology among the various alternatives; (3) Status and availability of the industrial infrastructure to support project design, equipment fabrication, facility construction, and process and program/project operation; (4) Adequacy of the design effort to provide a sound foundation to support execution of project; (5) Ability of the organization to fully integrate the system, and direct, manage, and control the execution of a complex major project

  8. Probabilistic safety assessment improves surveillance requirements in technical specifications

    International Nuclear Information System (INIS)

    Cepin, M.; Mavko, B.

    1997-01-01

    Probabilistic Safety Assessment is widely becoming the standard method for assessing, maintaining, assuring and improving the nuclear power plant safety. To achieve one of its many potential benefits, the optimization approach of surveillance requirements in technical specifications was developed. Surveillance requirements in technical specifications define the surveillance test intervals for the equipment to be tested and the testing strategy. This optimization approach based mainly on probabilistic safety assessment results consists of three levels: component level, system level and plant level. The application of this optimization approach on system level has shown that the risk based surveillance requirements differ from existing ones in technical specifications

  9. El Salvador - Formal Technical Education

    Data.gov (United States)

    Millennium Challenge Corporation — With a budget of nearly $20 million, the Formal Technical Education Sub-Activity was designed to strengthen technical and vocational educational institutions in the...

  10. Reactor component automatic grapple

    International Nuclear Information System (INIS)

    Greenaway, P.R.

    1982-01-01

    A grapple for handling nuclear reactor components in a medium such as liquid sodium which, upon proper seating and alignment of the grapple with the component as sensed by a mechanical logic integral to the grapple, automatically seizes the component. The mechanical logic system also precludes seizure in the absence of proper seating and alignment. (author)

  11. Principal component analysis

    NARCIS (Netherlands)

    Bro, R.; Smilde, A.K.

    2014-01-01

    Principal component analysis is one of the most important and powerful methods in chemometrics as well as in a wealth of other areas. This paper provides a description of how to understand, use, and interpret principal component analysis. The paper focuses on the use of principal component analysis

  12. Risk management through dynamic technical specifications

    International Nuclear Information System (INIS)

    Klopp, George T.; Petersen, Thomas A.

    2004-01-01

    The wide deployment of plant specific probabilistic risk assessments for nuclear power plants has provided the means to effect a fresh risk management perspective and a fresh, risk based, regulatory outlook on nuclear power. There has been a great deal of conversation on risk based regulation within the U. S. nuclear power industry but, curiously, very little on effective risk management. This paper proposes a means to link the two subjects through the plant Technical Specifications. A revised concept for Technical Specifications is suggested which is based on deterministic analyses and probabilistic risk assessments for each plant. The revised Technical Specifications would consider, on a real-time basis, the exact state of the plant in terms of the status of key components and systems. It would depict current plant risk levels and compare those levels to the desired and limiting (alert/action) levels. It would advise the plant operator on the risk impact of proposed actions through a simple query system and illustrate the impact of such actions on plant status relative to designated risk values. The basis for the proposed approach lies in realistic deterministic plant analyses and probabilistic risk assessment (PRA) deployment tools being developed, in parallel, by a number of parties in the U.S. today. These PRAs are based primarily on the existing plant responses to Generic Letter 88-20, 'Individual Plant Examinations' (IPEs). Each of these tools allows the plant operator to input, on a real-time basis, the status of key equipment and systems. The tools then provide explicit illustrations of dependency effects; updated, 'real-time' risk status indications such as core damage frequency; and, in some cases, allow the operator to assess the risk impact of removing from service selected components for maintenance or testing. These systems generally operate on personal computers and provide nearly instantaneous responses to plant queries. Moving from these tools to

  13. Technical Leadership Development Program

    Science.gov (United States)

    2010-12-13

    the traditional tenets of leadership and management , systems thinking, understanding SOS issues, and thinking and acting holistically. Our research...international element 2.0 Enterprise Leadership and Management UNCLASSIFIED Contract Number: H98230-08-D-0171 DO 002. TO002, RT 004 Report No...mechanisms for leadership of the overall technical effort, for systems engineering, for requirements, management , and for systems integration. o Develop

  14. Technical approach document

    International Nuclear Information System (INIS)

    1989-12-01

    The Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978, Public Law 95-604 (PL95-604), grants the Secretary of Energy the authority and responsibility to perform such actions as are necessary to minimize radiation health hazards and other environmental hazards caused by inactive uranium mill sites. This Technical Approach Document (TAD) describes the general technical approaches and design criteria adopted by the US Department of Energy (DOE) in order to implement remedial action plans (RAPS) and final designs that comply with EPA standards. It does not address the technical approaches necessary for aquifer restoration at processing sites; a guidance document, currently in preparation, will describe aquifer restoration concerns and technical protocols. This document is a second revision to the original document issued in May 1986; the revision has been made in response to changes to the groundwater standards of 40 CFR 192, Subparts A--C, proposed by EPA as draft standards. New sections were added to define the design approaches and designs necessary to comply with the groundwater standards. These new sections are in addition to changes made throughout the document to reflect current procedures, especially in cover design, water resources protection, and alternate site selection; only minor revisions were made to some of the sections. Sections 3.0 is a new section defining the approach taken in the design of disposal cells; Section 4.0 has been revised to include design of vegetated covers; Section 8.0 discusses design approaches necessary for compliance with the groundwater standards; and Section 9.0 is a new section dealing with nonradiological hazardous constituents. 203 refs., 18 figs., 26 tabs

  15. Technical training - Places available

    CERN Multimedia

    2012-01-01

    If you would like more information on a course, or for any other inquiry/suggestions, please contact Technical.Training@cern.ch Valeria Perez Reale, Learning Specialist, Technical Programme Coordinator (Tel.: 62424) Eva Stern and Elise Romero, Technical Training Administration (Tel.: 74924) HR Department Electronic Design Next Session Duration Language Availability Comprehensive VHDL for FPGA Design 08-Oct-12 to 12-Oct-12 5 days English 4 places Electrostatique / Protection ESD 28-Sep-12 to 28-Sep-12 3 hours French 25 places Impacts de la suppression du plomb (RoHS) en électronique 26-Oct-12 to 26-Oct-12 8 hours French 14 places Introduction to VHDL 10-Oct-12 to 11-Oct-12 2 days English 9 places LabVIEW Real Time and FPGA 13-Nov-12 to 16-Nov-12 5 days French 5 places LabVIEW for Experts 24-Sep-12 to 28-Sep-12 5 days English 6 places LabVIEW for beginners 15-Oct-12 to 17-...

  16. Resource Unavailability (RU) Per Domain Behavior

    NARCIS (Netherlands)

    Karagiannis, Georgios; Westberg, L.; Bader, A.; Tschofenig, Hannes; Tschofenig, H.

    2006-01-01

    This draft specifies a Per Domain Behavior that provides the ability to Diffserv nodes located outside Diffserv domain(s), e.g., receiver or other Diffserv enabled router to detect when the resources provided by the Diffserv domain(s) are not available. The unavailability of resources in the domain

  17. Optimal Transport for Domain Adaptation.

    Science.gov (United States)

    Courty, Nicolas; Flamary, Remi; Tuia, Devis; Rakotomamonjy, Alain

    2017-09-01

    Domain adaptation is one of the most challenging tasks of modern data analytics. If the adaptation is done correctly, models built on a specific data representation become more robust when confronted to data depicting the same classes, but described by another observation system. Among the many strategies proposed, finding domain-invariant representations has shown excellent properties, in particular since it allows to train a unique classifier effective in all domains. In this paper, we propose a regularized unsupervised optimal transportation model to perform the alignment of the representations in the source and target domains. We learn a transportation plan matching both PDFs, which constrains labeled samples of the same class in the source domain to remain close during transport. This way, we exploit at the same time the labeled samples in the source and the distributions observed in both domains. Experiments on toy and challenging real visual adaptation examples show the interest of the method, that consistently outperforms state of the art approaches. In addition, numerical experiments show that our approach leads to better performances on domain invariant deep learning features and can be easily adapted to the semi-supervised case where few labeled samples are available in the target domain.

  18. Texture of lipid bilayer domains

    DEFF Research Database (Denmark)

    Jensen, Uffe Bernchou; Brewer, Jonathan R.; Midtiby, Henrik Skov

    2009-01-01

    We investigate the texture of gel (g) domains in binary lipid membranes composed of the phospholipids DPPC and DOPC. Lateral organization of lipid bilayer membranes is a topic of fundamental and biological importance. Whereas questions related to size and composition of fluid membrane domain...

  19. Parallel pseudospectral domain decomposition techniques

    Science.gov (United States)

    Gottlieb, David; Hirsch, Richard S.

    1989-01-01

    The influence of interface boundary conditions on the ability to parallelize pseudospectral multidomain algorithms is investigated. Using the properties of spectral expansions, a novel parallel two domain procedure is generalized to an arbitrary number of domains each of which can be solved on a separate processor. This interface boundary condition considerably simplifies influence matrix techniques.

  20. Manageability of Technical Innovation through Technical Property Rights

    Directory of Open Access Journals (Sweden)

    Michael Horeth

    2016-06-01

    Full Text Available The term innovation is used in many respects and has been evolving over the last decades. This paper mainly focusses on managing technical innovation and differentiates this kind of innovation from others. For managing technical innovation, this work applies technical property rights, patents and utility models. The opportunity to protect the companies’ technical knowledge legally is, apart from strategic measurements like trade secrecy, a very valuable tool to manage and commercialize innovation considering the shift from closed to rather open innovation. This paper discusses the applicability of legal protection measurements for the management of technical innovation containing a critical appraisal.

  1. CEEM Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Bowers, John [Univ. of California, Santa Barbara, CA (United States)

    2014-11-26

    reactions that produce them. In response, the CEEM team developed well-defined molecular semiconductors that produce active layers with very high power conversion efficiencies, in other words they can convert a very high fraction of sunlight into useful electrical power. The fact that the semiconductor is formed from molecular species provides the basis for circumventing the unreliability of polymer counterparts and, as an additional bonus, allows one to attain much grater insight into the structure of the active layer. The latter is particularly important because efficient conversion is the result of a complex arrangement of two semiconductors that need to phase separate in a way akin to oil and water, but with domains that are described by nanoscale dimensions. CEEM was therefore able to provide deep insight into the influence of nanostructure, through the application of structural characterization tools and theoretical methods that describe how electrical charges migrate through the organic layer. Our research in light emitting diode (LED)-based solid state lighting (SSL) was directed at improving efficiency and reducing costs to enable the widespread deployment of economically-viable replacements for inefficient incandescent, halogen, and fluorescent-based lighting. Our specific focus was to advance the fundamental science and technology of light emitting diodes to both understand factors that limit efficiencies and to provide innovative and viable solutions to the current impediments. One of the main challenges we faced is the decrease in efficiency when LEDs are driven harder to increase light output---the so called “droop” effect. It requires large emitting surfaces to reach a desired optical output, and necessitates the use of costly heat sinks, both of which increase the cost. We successfully reduced droop by growing LED crystals having non-conventional orientations. As recognized by the award of the 2014 Nobel prize to the inventors of the nitride LEDs (one of

  2. Assessing Students' Technical Skill Attainment

    Science.gov (United States)

    Jorgensen, Haley

    2010-01-01

    The Wisconsin Technical College System (WTCS) is working to comply with the Carl D. Perkins Career and Technical Education Improvement Act of 2006 (Perkins) to ensure that its graduates have mastered the technical skills needed by business and industry. The legislation requires that each state identify and approve program assessment strategies…

  3. A pragmatic approach to IS development and Socio-Technical evaluation

    DEFF Research Database (Denmark)

    Madsen, Sabine; Vidgen, Richard

    , the research is that a focus on task satisfaction and socio-technical evaluation, rather than on the broader concept of job satisfaction and a full, traditional socio-technical analysis, was more acceptable in practice as it related more clearly to the IS domain. The paper presents a socio-technical evaluation......This paper provides an action research account of why and how UML use cases and socio-technical analysis were combined and used to support the development of an information system, using Multiview/WISDM as the framework of ideas. Significant learning points from, and the motivation for...

  4. Polar Domain Discovery with Sparkler

    Science.gov (United States)

    Duerr, R.; Khalsa, S. J. S.; Mattmann, C. A.; Ottilingam, N. K.; Singh, K.; Lopez, L. A.

    2017-12-01

    The scientific web is vast and ever growing. It encompasses millions of textual, scientific and multimedia documents describing research in a multitude of scientific streams. Most of these documents are hidden behind forms which require user action to retrieve and thus can't be directly accessed by content crawlers. These documents are hosted on web servers across the world, most often on outdated hardware and network infrastructure. Hence it is difficult and time-consuming to aggregate documents from the scientific web, especially those relevant to a specific domain. Thus generating meaningful domain-specific insights is currently difficult. We present an automated discovery system (Figure 1) using Sparkler, an open-source, extensible, horizontally scalable crawler which facilitates high throughput and focused crawling of documents pertinent to a particular domain such as information about polar regions. With this set of highly domain relevant documents, we show that it is possible to answer analytical questions about that domain. Our domain discovery algorithm leverages prior domain knowledge to reach out to commercial/scientific search engines to generate seed URLs. Subject matter experts then annotate these seed URLs manually on a scale from highly relevant to irrelevant. We leverage this annotated dataset to train a machine learning model which predicts the `domain relevance' of a given document. We extend Sparkler with this model to focus crawling on documents relevant to that domain. Sparkler avoids disruption of service by 1) partitioning URLs by hostname such that every node gets a different host to crawl and by 2) inserting delays between subsequent requests. With an NSF-funded supercomputer Wrangler, we scaled our domain discovery pipeline to crawl about 200k polar specific documents from the scientific web, within a day.

  5. Domain shape instabilities and dendrite domain growth in uniaxial ferroelectrics

    Science.gov (United States)

    Shur, Vladimir Ya.; Akhmatkhanov, Andrey R.

    2018-01-01

    The effects of domain wall shape instabilities and the formation of nanodomains in front of moving walls obtained in various uniaxial ferroelectrics are discussed. Special attention is paid to the formation of self-assembled nanoscale and dendrite domain structures under highly non-equilibrium switching conditions. All obtained results are considered in the framework of the unified kinetic approach to domain structure evolution based on the analogy with first-order phase transformation. This article is part of the theme issue `From atomistic interfaces to dendritic patterns'.

  6. Final Technical Report

    International Nuclear Information System (INIS)

    Diedhiou, Papa Madiallacke

    2010-01-01

    The established training programme, covering three months is structured over 2 main components: 1. Induced mutagenesis for the genetic improvement of Jatropha; 2. Genotyping using molecular markers in order to link phenotypic diversity to genotype.

  7. Durability of building materials and components

    CERN Document Server

    Delgado, JMPQ

    2013-01-01

    Durability of Building Materials and Components provides a collection of recent research works to contribute to the systematization and dissemination of knowledge related to the long-term performance and durability of construction and, simultaneously, to show the most recent advances in this domain. It includes a set of new developments in the field of durability, service life prediction methodologies, the durability approach for historical and old buildings, asset and maintenance management and on the durability of materials, systems and components. The book is divided in several chapters that intend to be a resume of the current state of knowledge for benefit of professional colleagues.

  8. Industrial application of domain specific languages combined with formal techniques

    NARCIS (Netherlands)

    Schuts, M.; Hooman, J.

    2016-01-01

    Two Domain Specific Languages (DSLs) have been developed to improve the development of a power control component of interventional X-ray systems of Philips. Configuration files and test cases are generated from instances of these DSLs. To increase the confidence in these instances and the

  9. Stochastic lattice model of synaptic membrane protein domains

    Science.gov (United States)

    Li, Yiwei; Kahraman, Osman; Haselwandter, Christoph A.

    2017-05-01

    Neurotransmitter receptor molecules, concentrated in synaptic membrane domains along with scaffolds and other kinds of proteins, are crucial for signal transmission across chemical synapses. In common with other membrane protein domains, synaptic domains are characterized by low protein copy numbers and protein crowding, with rapid stochastic turnover of individual molecules. We study here in detail a stochastic lattice model of the receptor-scaffold reaction-diffusion dynamics at synaptic domains that was found previously to capture, at the mean-field level, the self-assembly, stability, and characteristic size of synaptic domains observed in experiments. We show that our stochastic lattice model yields quantitative agreement with mean-field models of nonlinear diffusion in crowded membranes. Through a combination of analytic and numerical solutions of the master equation governing the reaction dynamics at synaptic domains, together with kinetic Monte Carlo simulations, we find substantial discrepancies between mean-field and stochastic models for the reaction dynamics at synaptic domains. Based on the reaction and diffusion properties of synaptic receptors and scaffolds suggested by previous experiments and mean-field calculations, we show that the stochastic reaction-diffusion dynamics of synaptic receptors and scaffolds provide a simple physical mechanism for collective fluctuations in synaptic domains, the molecular turnover observed at synaptic domains, key features of the observed single-molecule trajectories, and spatial heterogeneity in the effective rates at which receptors and scaffolds are recycled at the cell membrane. Our work sheds light on the physical mechanisms and principles linking the collective properties of membrane protein domains to the stochastic dynamics that rule their molecular components.

  10. Stochastic lattice model of synaptic membrane protein domains.

    Science.gov (United States)

    Li, Yiwei; Kahraman, Osman; Haselwandter, Christoph A

    2017-05-01

    Neurotransmitter receptor molecules, concentrated in synaptic membrane domains along with scaffolds and other kinds of proteins, are crucial for signal transmission across chemical synapses. In common with other membrane protein domains, synaptic domains are characterized by low protein copy numbers and protein crowding, with rapid stochastic turnover of individual molecules. We study here in detail a stochastic lattice model of the receptor-scaffold reaction-diffusion dynamics at synaptic domains that was found previously to capture, at the mean-field level, the self-assembly, stability, and characteristic size of synaptic domains observed in experiments. We show that our stochastic lattice model yields quantitative agreement with mean-field models of nonlinear diffusion in crowded membranes. Through a combination of analytic and numerical solutions of the master equation governing the reaction dynamics at synaptic domains, together with kinetic Monte Carlo simulations, we find substantial discrepancies between mean-field and stochastic models for the reaction dynamics at synaptic domains. Based on the reaction and diffusion properties of synaptic receptors and scaffolds suggested by previous experiments and mean-field calculations, we show that the stochastic reaction-diffusion dynamics of synaptic receptors and scaffolds provide a simple physical mechanism for collective fluctuations in synaptic domains, the molecular turnover observed at synaptic domains, key features of the observed single-molecule trajectories, and spatial heterogeneity in the effective rates at which receptors and scaffolds are recycled at the cell membrane. Our work sheds light on the physical mechanisms and principles linking the collective properties of membrane protein domains to the stochastic dynamics that rule their molecular components.

  11. Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines.

    Science.gov (United States)

    González, Alvaro J; Liao, Li

    2010-10-29

    Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods have motivated the development of computational methods for predicting PPIs. As protein interactions generally occur via domains instead of the whole molecules, predicting domain-domain interaction (DDI) is an important step toward PPI prediction. Computational methods developed so far have utilized information from various sources at different levels, from primary sequences, to molecular structures, to evolutionary profiles. In this paper, we propose a computational method to predict DDI using support vector machines (SVMs), based on domains represented as interaction profile hidden Markov models (ipHMM) where interacting residues in domains are explicitly modeled according to the three dimensional structural information available at the Protein Data Bank (PDB). Features about the domains are extracted first as the Fisher scores derived from the ipHMM and then selected using singular value decomposition (SVD). Domain pairs are represented by concatenating their selected feature vectors, and classified by a support vector machine trained on these feature vectors. The method is tested by leave-one-out cross validation experiments with a set of interacting protein pairs adopted from the 3DID database. The prediction accuracy has shown significant improvement as compared to InterPreTS (Interaction Prediction through Tertiary Structure), an existing method for PPI prediction that also uses the sequences and complexes of known 3D structure. We show that domain-domain interaction prediction can be significantly enhanced by exploiting information inherent in the domain profiles via feature selection based on Fisher scores, singular value decomposition and supervised learning based on support vector machines. Datasets and source code are freely available on the web at http

  12. Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines

    Directory of Open Access Journals (Sweden)

    Liao Li

    2010-10-01

    Full Text Available Abstract Background Protein-protein interaction (PPI plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods have motivated the development of computational methods for predicting PPIs. As protein interactions generally occur via domains instead of the whole molecules, predicting domain-domain interaction (DDI is an important step toward PPI prediction. Computational methods developed so far have utilized information from various sources at different levels, from primary sequences, to molecular structures, to evolutionary profiles. Results In this paper, we propose a computational method to predict DDI using support vector machines (SVMs, based on domains represented as interaction profile hidden Markov models (ipHMM where interacting residues in domains are explicitly modeled according to the three dimensional structural information available at the Protein Data Bank (PDB. Features about the domains are extracted first as the Fisher scores derived from the ipHMM and then selected using singular value decomposition (SVD. Domain pairs are represented by concatenating their selected feature vectors, and classified by a support vector machine trained on these feature vectors. The method is tested by leave-one-out cross validation experiments with a set of interacting protein pairs adopted from the 3DID database. The prediction accuracy has shown significant improvement as compared to InterPreTS (Interaction Prediction through Tertiary Structure, an existing method for PPI prediction that also uses the sequences and complexes of known 3D structure. Conclusions We show that domain-domain interaction prediction can be significantly enhanced by exploiting information inherent in the domain profiles via feature selection based on Fisher scores, singular value decomposition and supervised learning based on support vector machines. Datasets and source code are freely available on

  13. GRS knowledge base ''Safety of pressure-bearing components'' - An example of knowledge management of a technical support organisation; GRS-Wissensbasis ''Sicherheit druckfuehrender Komponenten'' - Ein Beispiel zum Wissensmanagement einer Sachverstaendigenorganisation

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, H.; Michel, F. [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (GRS), Koeln (Germany)

    2005-07-01

    In long-lived technical systems, the main challenge is in preserving knowledge on all technical aspects throughout the plant life as several generations of engineers are involved from projecting to decommissioning. A technical support organisation has access to knowledge on safety requirements and their development with time, relevant damage cases both in Germany and abroad, research projects and analyses as well as expert documentations. A modern working environment enables fast access to, and combination of, distributed parts of knowledge provided that some prestructuring is ensured. The contribution presents an exemplary information system of GRS, whose elements may be of interest to other organisations as well. [German] Fuer technische Anlagen mit langen Lebenszeiten ist es eine besondere Herausforderung, das erforderliche Wissen zu allen technischen Sachverhalten jederzeit verfuegbar zu haben. Von der Projektierung bis zum Betriebsende einer Anlage sind mehrere Generationen von Ingenieuren mit den jeweiligen Sachverhalten befasst. Fuer eine Sachverstaendigenorganisation stehen Kenntnisse zu den sicherheitstechnischen Anforderungen und deren zeitlicher Entwicklung, relevanten Schadensereignissen im In- und Ausland, Erkenntnisse aus Forschungsvorhaben und Analysen sowie die Verfuegbarkeit des weiteren dokumentierten Fachwissens und technischer Experten im Vordergrund. Die moderne Arbeitsumgebung erlaubt heute ein schnelles Auffinden und Zusammenfuehren der vorhandenen Wissensbausteine. Eine sinnvolle Vorstrukturierung als Wegweiser im Dschungel der Informationen ist jedoch unerlaesslich. Ein auf die Beduerfnisse der GRS zugeschnittenes Beispiel wird im Einzelnen vorgestellt. Wesentliche Elemente der Struktur fuer ein praktikables Wissensmanagement sind auch fuer andere Organisationen nutzbar.

  14. Technics and ethics

    International Nuclear Information System (INIS)

    Budnick, D.; Gemmel, F.

    1981-01-01

    Questions about the sense of life and the responsibility of technology are ethical questions. Young people in our neighbourhood who, compared to some time ago, see, hear and read much more of the world, deal with them increasingly. However, the permanent stream of information does not at all facilitate orientation but prevents many people from gaining some clearness about their own point of view. In asking the questions: where are we today. How can we get on. How can we start. The relation between ethics and technics is discussed under various aspects. (orig./HSCH) [de

  15. INOPS Technical Report

    DEFF Research Database (Denmark)

    Lindholst, Andrej Christian

    This research report contains background analyses and findings from the INOPS research project. The purpose of the INOPS project was, from an international perspective, to describe, analyse and recommend different forms of contracting out and public–private co-operations within the technical area...... in Denmark, Sweden, Norway and England. The research report addresses three key research questions in a comparative perspective: 1. Why are park and road maintenance services contracted out? 2. How are park and road maintenance services contracted out? 3. What are the outcomes from contracting out park...

  16. Argentina technical report

    International Nuclear Information System (INIS)

    2002-01-01

    At present, the Production Cyclotron Facility, installed at the Ezeiza Atomic Centre, is used for Tl-201 production; F-18 and I-123 production will be incorporated during this year. Concerning I-123 production, a system for irradiation of gaseous target has been developed in the frame of the IAEA Technical Assistance Project (ARG4085). The iodine production system delivers an ultra pure radioisotope via nuclear reactions: 124 Xe (p,2n) 123 Cs → 123 Xe → 123 I and 124 Xe (p,pn) 123 Xe → 123 I. This report describes the target and irradiation chamber design, the radiochemical purification process

  17. HPCG Benchmark Technical Specification

    Energy Technology Data Exchange (ETDEWEB)

    Heroux, Michael Allen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Dongarra, Jack [Univ. of Tennessee, Knoxville, TN (United States); Luszczek, Piotr [Univ. of Tennessee, Knoxville, TN (United States)

    2013-10-01

    The High Performance Conjugate Gradient (HPCG) benchmark [cite SNL, UTK reports] is a tool for ranking computer systems based on a simple additive Schwarz, symmetric Gauss-Seidel preconditioned conjugate gradient solver. HPCG is similar to the High Performance Linpack (HPL), or Top 500, benchmark [1] in its purpose, but HPCG is intended to better represent how today’s applications perform. In this paper we describe the technical details of HPCG: how it is designed and implemented, what code transformations are permitted and how to interpret and report results.

  18. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Sobecky, Patricia A; Taillefert, Martial

    2013-03-29

    This final technical report describes results and findings from a research project to examine the role of microbial phosphohydrolase enzymes in naturally occurring subsurface microorganisms for the purpose of promoting the immobilization of the radionuclide uranium through the production of insoluble uranium phosphate minerals. The research project investigated the microbial mechanisms and the physical and chemical processes promoting uranium biomineralization and sequestration in oxygenated subsurface soils. Uranium biomineralization under aerobic conditions can provide a secondary biobarrier strategy to immobilize radionuclides should the metal precipitates formed by microbial dissimilatory mechanisms remobilize due to a change in redox state.

  19. RADTRAN 6 technical manual.

    Energy Technology Data Exchange (ETDEWEB)

    Weiner, Ruth F.; Neuhauser, Karen Sieglinde; Heames, Terence John; O' Donnell, Brandon M.; Dennis, Matthew L.

    2014-01-01

    This Technical Manual contains descriptions of the calculation models and mathematical and numerical methods used in the RADTRAN 6 computer code for transportation risk and consequence assessment. The RADTRAN 6 code combines user-supplied input data with values from an internal library of physical and radiological data to calculate the expected radiological consequences and risks associated with the transportation of radioactive material. Radiological consequences and risks are estimated with numerical models of exposure pathways, receptor populations, package behavior in accidents, and accident severity and probability.

  20. RADTRAN 6 Technical Manual

    Energy Technology Data Exchange (ETDEWEB)

    Weiner, Ruth F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Neuhauser, Karen Sieglinde [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Heames, Terence John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); O' Donnell, Brandon M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Dennis, Matthew L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-01-01

    This Technical Manual contains descriptions of the calculation models and mathematical and numerical methods used in the RADTRAN 6 computer code for transportation risk and consequence assessment. The RADTRAN 6 code combines user-supplied input data with values from an internal library of physical and radiological data to calculate the expected radiological consequences and risks associated with the transportation of radioactive material. Radiological consequences and risks are estimated with numerical models of exposure pathways, receptor populations, package behavior in accidents, and accident severity and probability.

  1. Wavefield extrapolation in pseudodepth domain

    KAUST Repository

    Ma, Xuxin

    2013-02-01

    Wavefields are commonly computed in the Cartesian coordinate frame. Its efficiency is inherently limited due to spatial oversampling in deep layers, where the velocity is high and wavelengths are long. To alleviate this computational waste due to uneven wavelength sampling, we convert the vertical axis of the conventional domain from depth to vertical time or pseudodepth. This creates a nonorthognal Riemannian coordinate system. Isotropic and anisotropic wavefields can be extrapolated in the new coordinate frame with improved efficiency and good consistency with Cartesian domain extrapolation results. Prestack depth migrations are also evaluated based on the wavefield extrapolation in the pseudodepth domain.© 2013 Society of Exploration Geophysicists. All rights reserved.

  2. TECHNICAL TRAINING SEMINAR: National Instruments

    CERN Multimedia

    Monique Duval

    2004-01-01

    From 9:30 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Data acquisition systems on PCs, industrial measurement and control techniques, advanced LabVIEW software and PXI instrumentation, and system components for tests and automation will be presented. Walk-in courses will address DIAdem, LabVIEW and data acquisition. Language: English and French Free seminars and courses, no registration Organisers: Rolf Stampfli / IT-CO / 78102 & 160367 / Rolf.Stampfli@cern.ch Davide Vitè / HR-PMD-ATT / 75141 Davide.Vite@cern.ch For more information and the complete event programme, please visit the...

  3. Technical Evolution of Medical Endoscopy

    Directory of Open Access Journals (Sweden)

    S. Gross

    2009-01-01

    Full Text Available This paper gives a summary of the technical evolution of medical endoscopy. The first documented redirection of sunlight into the human body dates back to the 16th century. Rigid tubes with candle light were given a trial later on. Low light intensity forced the development of alternative light sources. Some of these experiments included burning chemical components. Electric lighting finally solved the problems of heat production and smoke. Flexible endoscopy increased the range of medical examinations as it allowed access to tight and angular body cavities. The first cameras for endoscopic applications made taking photos from inside the human body possible. Later on, digital video endoscopy made endoscopes easier to use and allowed multiple spectators to observe the endoscopic intervention. Swallowable capsules called pill-cams made endoscopic examinations of the small intestine possible. Modern technologies like narrow band imaging and fluorescence endoscopy increased the diagnostic significance of endoscopic images. Today, image processing is applied to decrease noise and enhance image quality. These enhancements have made medical endoscopy an invaluable tool in many diagnostic processes. In closing, an example is given of an interdisciplinary examination, which is taken from the archaeological field. 

  4. TECHNICAL SUPPORT AS A BASIS OF HIGH AVAILABILITY LEVEL AND IT SYSTEM SERVICE QUALITY

    Directory of Open Access Journals (Sweden)

    Dejan Vidojevic

    2007-06-01

    Full Text Available This work presents the development and implementation methodology of technical support in IT1system operation. Methodology is developed and applied in realistic system (Information system of the Tax administration - DIS 2003, which is technically very complex and highly distributed. The results of IT system availability assessment and identification of the critical components are input parameters in the process of establishing of the technical support. The importance of technical support for achieving optimal IT system availability and IT service quality is assessed according to its operation during one year. The history of technical support system operation is a basis for further continuous improvement.

  5. Components of Adenovirus Genome Packaging

    Science.gov (United States)

    Ahi, Yadvinder S.; Mittal, Suresh K.

    2016-01-01

    Adenoviruses (AdVs) are icosahedral viruses with double-stranded DNA (dsDNA) genomes. Genome packaging in AdV is thought to be similar to that seen in dsDNA containing icosahedral bacteriophages and herpesviruses. Specific recognition of the AdV genome is mediated by a packaging domain located close to the left end of the viral genome and is mediated by the viral packaging machinery. Our understanding of the role of various components of the viral packaging machinery in AdV genome packaging has greatly advanced in recent years. Characterization of empty capsids assembled in the absence of one or more components involved in packaging, identification of the unique vertex, and demonstration of the role of IVa2, the putative packaging ATPase, in genome packaging have provided compelling evidence that AdVs follow a sequential assembly pathway. This review provides a detailed discussion on the functions of the various viral and cellular factors involved in AdV genome packaging. We conclude by briefly discussing the roles of the empty capsids, assembly intermediates, scaffolding proteins, portal vertex and DNA encapsidating enzymes in AdV assembly and packaging. PMID:27721809

  6. Supply chain components

    Directory of Open Access Journals (Sweden)

    Vieraşu, T.

    2011-01-01

    Full Text Available In this article I will go through three main logistics components, which are represented by: transportation, inventory and facilities, and the three secondary logistical components: information, production location, price and how they determine performance of any supply chain. I will discuss then how these components are used in the design, planning and operation of a supply chain. I will also talk about some obstacles a supply chain manager may encounter.

  7. Supply chain components

    OpenAIRE

    Vieraşu, T.; Bălăşescu, M.

    2011-01-01

    In this article I will go through three main logistics components, which are represented by: transportation, inventory and facilities, and the three secondary logistical components: information, production location, price and how they determine performance of any supply chain. I will discuss then how these components are used in the design, planning and operation of a supply chain. I will also talk about some obstacles a supply chain manager may encounter.

  8. Magnetohydrodynamic projects at the CDIF (Component Development and Integration Facility)

    Energy Technology Data Exchange (ETDEWEB)

    1990-01-01

    This quarterly technical progress report presents the tasks accomplished at the Component Development and Integration Facility during the fourth quarter of FY90. Areas of technical progress this quarter included: coal system development; seed system development; test bay modification; channel power dissipation and distribution system development; oxygen system storage upgrade; iron core magnet thermal protection system oxygen checkout; TRW slag rejector/CDIF slag removal project; stack gas/environmental compliance upgrade; coal-fired combustor support; 1A channels fabrication and assembly; support of Mississippi State University diagnostic testing; test operations and results; data enhancement; data analysis and modeling; technical papers; and projected activities. 2 tabs.

  9. Disentangling the impact of artistic creativity on creative thinking, working memory, attention and intelligence:Evidence for domain-specific relationships with a new self-report questionnaire

    OpenAIRE

    Katrin Lunke; Beat Meier

    2016-01-01

    The goal of the present study was to take a new look at the relationship between creativity and cognitive functioning. Based on models that have postulated domain- and sub-domain-structures for different forms of creativity, like scientific, technical or artistic creativity with cognitive functions as important basis, we developed a new questionnaire. The Artistic Creativity Domains Compendium (ACDC) assesses interest, ability and performance in a distinct way for different domains of artisti...

  10. Domain decomposition methods for the neutron diffusion problem

    International Nuclear Information System (INIS)

    Guerin, P.; Baudron, A. M.; Lautard, J. J.

    2010-01-01

    The neutronic simulation of a nuclear reactor core is performed using the neutron transport equation, and leads to an eigenvalue problem in the steady-state case. Among the deterministic resolution methods, simplified transport (SPN) or diffusion approximations are often used. The MINOS solver developed at CEA Saclay uses a mixed dual finite element method for the resolution of these problems. and has shown his efficiency. In order to take into account the heterogeneities of the geometry, a very fine mesh is generally required, and leads to expensive calculations for industrial applications. In order to take advantage of parallel computers, and to reduce the computing time and the local memory requirement, we propose here two domain decomposition methods based on the MINOS solver. The first approach is a component mode synthesis method on overlapping sub-domains: several Eigenmodes solutions of a local problem on each sub-domain are taken as basis functions used for the resolution of the global problem on the whole domain. The second approach is an iterative method based on a non-overlapping domain decomposition with Robin interface conditions. At each iteration, we solve the problem on each sub-domain with the interface conditions given by the solutions on the adjacent sub-domains estimated at the previous iteration. Numerical results on parallel computers are presented for the diffusion model on realistic 2D and 3D cores. (authors)

  11. Hot gas path component

    Science.gov (United States)

    Lacy, Benjamin Paul; Kottilingam, Srikanth Chandrudu; Porter, Christopher Donald; Schick, David Edward

    2017-09-12

    Various embodiments of the disclosure include a turbomachine component. and methods of forming such a component. Some embodiments include a turbomachine component including: a first portion including at least one of a stainless steel or an alloy steel; and a second portion joined with the first portion, the second portion including a nickel alloy including an arced cooling feature extending therethrough, the second portion having a thermal expansion coefficient substantially similar to a thermal expansion coefficient of the first portion, wherein the arced cooling feature is located within the second portion to direct a portion of a coolant to a leakage area of the turbomachine component.

  12. CORE COMPONENT POT

    Energy Technology Data Exchange (ETDEWEB)

    MARTIN RL; OMBERG RP

    1975-12-19

    The core component pot is an open top vessel used to hold both new and irradiated core components for storage in the IDS and for holding the components submerged in sodium while being trasported inside CLEM. The top of the CCP is equipped with a grapple lip which is engaged by the hoisting grapples. Heat for maintaining the preheat of new components and dissipation of decay heat of irradiated fuel assemblies is conducted between the wall of the pot and the surrounding environment by thermal radiation and convection.

  13. Facilitating Inter-Domain Synergies in Ambient Assisted Living Environments.

    Science.gov (United States)

    Schwartze, Jonas; Schrom, Harald; Wolf, Klaus-Hendrik; Marschollek, Michael

    2016-01-01

    Current Ambient Assisted Living (AAL) environments lack integration of sensors and actuators of other sub-domains. Creating technical and organizational integration is addressed by the BASIS project (Build Automation by a Scalable and Intelligent System), which aims to build a cross-domain home bus system. The main objective of this paper is to present an overview of design, architecture and state of realization of BASIS by describing the requirements development process, underlying hardware design and software architecture. We built a distributed system of one independent building manager with several redundantly meshed segment controllers, each controlling a bus segment with any number of bus nodes. The software system layer is divided into logical partitions representing each sub-domain. Structured data storage is possible with a special FHIR based home centered data warehouse. The system has been implemented in six apartments running under daily living conditions. BASIS integrates a broad range of sub-domains, which poses challenges to all project partners in terms of a common terminology, and project management methods, but enables development of inter-domain synergies like using the same sensor and actuator hardware for a broad range of services and use cases.

  14. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: Hands-on Introduction to Python Programming: 28 - 30.6.2005 (3 days) Introduction to ANSYS: 28.6 - 1.7.2005 (4 days) IT3T/3 - Working remotely with Windows XP: 28.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/4 - Editing Websites with Frontpage 2003: 30.6.2005 (IT Technical Training Tutorial, free of charge) LabVIEW base 1 : 4 - 6.7.2005 (3 jours) LabVIEW Basics 2: 7 - 8.7.2005 (2 days) Utilisation des fichiers PDF avec ACROBAT 7.0 : 5.7.2005 (1 jour) FrontPage 2003 - niveau 1 : 6-7.7.2005 (2 jours) WORD 2003 (Short Course I) - HowTo... Work with repetitive tasks /AutoText, AutoFormat, AutoCorrect, Find/Replace) : 4.7.2005 (afternoon) WORD 2003 (Short Course II) - HowTo... Mail merge: 5.7.2005 (afternoon) WORD 2003 (Short Course III) - HowTo... Work with long documents : 6.7.2005 (afternoon) ACCES...

  15. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: Joint PVSS JCOP Framework: 8 - 12.8.2005 (5 days) FrontPage 2003 - niveau 1 : 1 - 2.9.2005 (2 jours) Utilisation des fichiers PDF avec ACROBAT 7.0 : 5.9.2005 (1 jour) LabVIEW Basics 1 : 5 - 7.9.2005 (3 days, dates to be confirmed) Introduction à Windows XP au CERN : 12.9.2005 (1 demi-journée) FrontPage 2003 - niveau 2 : 15 - 16.9.2005 (2 jours) AutoCAD 2005 - niveau 1 : 22, 23, 28, 29.9.2005 (4 jours) MAGNE-05 - Magnétisme pour l'électrotechnique : 27 - 29.9.2005 (3 jours) LabVIEW Application Development (Intermediate I): 5 - 7.12.2005 (3 days) LabVIEW Advanced Programming (Intermediate 2): 8 - 9.12.2005 (2 days) ENSEIGNEMENT TECHNIQUE TECHNICAL TRAINING Monique Duval 74924 technical.training@cern.ch

  16. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2005-01-01

    The number of places available may vary. Please check our Web site to find out the current availability. Places are available on the following courses: Hands-on Introduction to Python Programming: 28 - 30.6.2005 (3 days) Introduction to ANSYS: 21 - 24.6.2005 (4 days) IT3T/3 - Working remotely with Windows XP: 28.6.2005 (IT Technical Training Tutorial, free of charge) IT3T/4 - Editing Websites with Frontpage 2003: 30.6.2005 (IT Technical Training Tutorial, free of charge) Utilisation des fichiers PDF avec ACROBAT 7.0 : 5.7.2005 (1 jour) FrontPage 2003 - niveau 1 : 6-7.7.2005 (2 jours) LabVIEW base 1 : 4 - 6.7.2005 (3 jours) LabVIEW Basics 2: 7 - 8.7.2005 (2 days) WORD 2003 (Short Course I) - HowTo... Work with repetitive tasks /AutoText, AutoFormat, AutoCorrect, Find/Replace) : 4.7.2005 (afternoon) WORD 2003 (Short Course II) - HowTo... Mail merge: 5.7.2005 (afternoon) WORD 2003 (Short Course III) - HowTo (4 mornings) EXCEL 2003 (Short Course I) - HowTo... Work ...

  17. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: C++ for Particle Physicists : 8 - 12.3.2004 (6 X 4-hour sessions) Introduction to the CERN EDMS : 9.3.2004 (1 day, free of charge) The EDMS MTF in Practice : 10.3.2004 (morning, free of charge) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon, free of charge) The CERN EDMS for Engineers : 11.3.2004 (1 day, free of charge) LabVIEW...

  18. Technical Training: Places available

    CERN Document Server

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Instructor-led WBTechT study or follow-up for Microsoft applications : 1.4.2004 (morning) FrontPage XP - niveau 1 : 5 & 6.4.2004 (2 jours) AutoCAD 2002 - niveau 1 : 19, 20.4 et 3, 4.5.2004 (4 jours) Oracle 8i/9i - Develop Web-based Applications with PL/SQL : 19 & 20.4.2004 (2 days) Introduction to ANSYS : 20 - 23.4.2004 (4 day...

  19. Technical Training: Places available

    CERN Document Server

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: LabVIEW base 1 : 25 - 27.2.2004(3 jours) Instructor-led WBTechT study or follow-up for Microsoft applications : 26.2.2004 (morning) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon - free of charge) C++ for Particle Physicists : 8 - 12.3.2004 (6 X 4-hour sessions) LabVIEW hands-on (E) : 16.3.2004 (afternoon) LabVIEW Basics 1 : 22 - 24.3.2004 ...

  20. TECHNICAL TRAINING: Places available**

    CERN Multimedia

    2003-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval Tel. 74924 technical.training@cern.ch ** The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: The EDMS-MTF in practice (free of charge) : 28 -  30.10.03 (6 half-day sessions) AutoCAD 2002 – Level 1 : 3, 4, 12, 13.11.03 (4 days) LabVIEW TestStand ver. 3 : 4 & 5.11.03 (2 days) Introduction to PSpice : 4.11.03 p.m. (half-day) Hands-on Introduction to Python Programming : 12 – 14.11.03 (3 days) ACCESS ...

  1. Technical Training: Places available

    CERN Document Server

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Computational Electromagnetics with the ELEKTRA Module of OPERA-3D : 27 & 28.4.2004 (2 days) Hands-on Introduction to Python Programming : 3 - 5.5.2004 (3 days) LabVIEW Base 2 : 6 & 7.5.2004 (2 jours) Project Planning with MS-Project : 6 & 13.5.2004 (2 days) Word 2003 - niveau 1 : 10 & 11.5.2004 (2 jours) Oracle 9i : SQL : 10 - 12.5.2004 (3...

  2. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Project Planning with MS-Project :6 & 13.5.2004 (2 days) Word 2003 - niveau 1 : 10 & 11.5.2004 (2 jours) Oracle 9i : SQL : 17 - 19.5.2004 (3 days) Word 2003 - niveau 2 : 24 & 25.5.2004 (2 jours) EXCEL 2003 - niveau 1: 27 & 28.5.2004 (2 jours) STEP7 Programming Level 1 : 1 - 4.6.2004 (4 days) Oracle 9i : Programming with PL/SQL : 2 - 4.6.2...

  3. Technical Training: Places available

    CERN Document Server

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Instructor-led WBTechT study for Microsoft applications :12.2.2004 (morning) Instructor-led WBTechT study or follow-up for Microsoft applications : 19.2.2004 (morning) LabVIEW TestStand I (E) : 23 & 24.2.2004 (2 days) LabVIEW base 1 : 25 - 27.2.2004 (3 jours) Instructor-led WBTechT study or follow-up for Microsoft applications : 19.2.2004 (morning) CLEAN-2002 ...

  4. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: AutoCAD 2002 - niveau 1 : 19, 20.4 et 3, 4.5.2004 (4 jours) Oracle 8i/9i - Develop Web-based Applications with PL/SQL : 19 & 20.4.2004 (2 days) Introduction to ANSYS : 20 - 23.4.2004 (4 days) LabVIEW Hands-on : 20.4.2004 (half-day, p.m.) FrontPage XP - niveau 2 : 26 & 27.4.2004 (2 jours) The Joint PVSS JCOP Framework : 26 -...

  5. Technical Training: Places available**

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch ** The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: The JAVA Programming Language Level 1 : 9 & 10.1.2004 (2 days) LabVIEW TestStand I (E) : 23 & 24.2.2004 (2 days) LabVIEW base 1 : 25 - 27.2.2004 (3 jours) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon - free of charge) C++ for Particle Physicists : 8 - 12.3.2004 ( 6 X 4-hour sessions) LabVIEW hands-on (E) 16.3...

  6. Technical Training: Places available

    CERN Document Server

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Instructor-led WBTechT study or follow-up for Microsoft applications : 19.2.2004 (morning) LabVIEW TestStand I (E) : 23 & 24.2.2004 (2 days) LabVIEW base 1 : 25 - 27.2.2004 (3 jours) Instructor-led WBTechT study or follow-up for Microsoft applications : 26.2.2004 (morning) CLEAN-2002 : Working in a Cleanroom : 10.3.2004 (afternoon - free of charge) C++ for Pa...

  7. Technical Training: Places available

    CERN Document Server

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. Technical Training Monique Duval - Tel.74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Word 2003 - niveau 2 : 24 & 25.5.2004 (2 jours) VisualEliteHDL : 25 & 26.5.2004 (2 days) EXCEL 2003 - niveau 1 : 27 & 28.5.2004 (2 jours) STEP7 Programming Level 1: 1 - 4.6.2004 (4 days) Oracle 9i : Programming with PL/SQL: 2 - 4.6.2004 (3 days) CST Microwave Studio: 3 & 4.6.2004 (2 days) Oracle 9...

  8. Technical Training: Places Available

    CERN Document Server

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training' form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. Technical Training Monique Duval - Tel.74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Oracle 9i: SQL: 17 - 19.5.2004 (3 days) Word 2003 - niveau 2 : 24 & 25.5.2004 (2 jours) EXCEL 2003 - niveau 1 : 27 & 28.5.2004 (2 jours) STEP7 Programming Level 1: 1 - 4.6.2004 (4 days) Oracle 9i : Programming with PL/SQL: 2 - 4.6.2004 (3 days) CST Microwave Studio: 3 & 4.6.2004 (2 days) Oracle 9i : New f...

  9. Technical Training: Places available

    CERN Multimedia

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: FrontPage XP - niveau 2 : 26 & 27.4.2004 (2 jours) The Joint PVSS JCOP Framework : 26 - 30.4.2004 (5 days) Computational Electromagnetics with the ELEKTRA Module of OPERA-3D : 27 & 28.4.2004 (2 days) Hands-on Introduction to Python Programming : 3 - 5.5.2004 (3 days) LabVIEW Base 2 : 6 & 7.5.2004 (2 jours) Project Pla...

  10. TECHNICAL TRAINING: Places available**

    CERN Document Server

    2003-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch ** The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: Hands-on Introduction to Python Programming : 12 - 14.11.03(3 days) ACCESS 2000 - niveau 1 : 13 & 14.11.03 (2 jours) C++ for Particle Physicists : 17 - 21.11.03 (6 X 3-hour lectures) Programmation automate Schneider TSX Premium - niveau 2 : 18 - 21.11.03 (4 jours) Project Planning with MS-Project  (free of charg...

  11. Technical Training: Places available

    CERN Multimedia

    Monique Duval

    2004-01-01

    If you wish to participate in one of the following courses, please discuss with your supervisor and apply electronically directly from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an "application for training" form available from your Divisional Secretariat or from your DTO (Divisional Training Officer). Applications will be accepted in the order of their receipt. TECHNICAL TRAINING Monique Duval tel. 74924 technical.training@cern.ch The number of places available may vary. Please check our Web site to find out the current availability. Places are available in the following courses: C++ for Particle Physicists : 8 - 12.3.2004 (6 X 4-hour sessions) Introduction to the CERN EDMS : 9.3.2004 (1 day, free of charge) The EDMS MTF in Practice : 10.3.2004 (morning, free of charge) CLEAN-2002: Working in a Cleanroom : 10.3.2004 (afternoon, free of charge) The CERN EDMS for Engineers : 11.3.2004 (1 day, free of charge) LabVIEW hands-on (E):...

  12. Technical training: places available

    CERN Multimedia

    HR Department

    2007-01-01

    CERN Technical Training: Open Courses (April - June 2007) The following course sessions are currently scheduled in the framework of the CERN Technical Training Programme 2007:   AutoCAD 2006 - niveau 1 (course in French): 25.4.- 26.4.2007 & 2.5. - 3.5.2007 (4 days in 2 modules, 5 places available) AutoCAD 2006 - niveau 1 (course in French): 27.6.- 28.6.2007 & 3.7. - 4.7.2007 (4 days in 2 modules, 5 places available) AutoCAD Mechanical 2006 (course in French) 21.6.-22.6.2007 (2 days, 8 places available) * NEW COURSE* Automate de securite S7 (course in French) 14.5.-16.5.2007 (3 days, 4 places available) * NEW COURSE* Automate de securite S7 (course in French): 9.5.-11.5.2007 (3 days, 4 places available) JCOP - Joint PVSS-JCOP Frameswork (course in English): 21.5.-25.5.2007 (5 days, 12 places available) JCOP - Finite State Machines in the JCOP Frameswork (course in English): 12.6.-14.6.2007 (3 days, 12 places available) LabVIEW Basics 1 (in English): 2.-4.5.2007 (3 days, 7 places ...

  13. TECHNICAL TRAINING SEMINAR

    CERN Multimedia

    Davide Vitè

    2002-01-01

    Wednesday 6 March TECHNICAL TRAINING SEMINAR from 9:30 to 16:45 - IT Amphitheatre - bldg. 31.3.004 Analog Devices DSP Day Thorsten Kistler (Application Engineer), Steffen Boerner (Product Specialist) / ANALOG DEVICES Munich Trying to meet your design challenges, Analog Devices compiles application information and offers chipsets, software, reference designs and mixed-signal, application specific DSPs, for a range of real-time signal processing applications. This seminar will present the latest 16bit fixed-point and 32bit floating-point DSPs (roadmaps; internal architectures, blocks, features benchmarks), with their software, development kits and emulators: Fixed-Point DSP-Family, ADSP-218x and ADSP-219x Blackfin DSP SHARC-Family, 2106x and 2116x TigerSHARC Industrial Contact: François Caloz, Sasco-Spoerle GmbH Language: English Free seminar, no registration Organiser: Davide Vitè / HR-TD / 75141 Davide.Vite@cern.ch Please read the full information on the Technical Training Seminars...

  14. METHOD IMPROVEMENT FOR DETERMINING THE TECHNICAL LEVEL OF CIVIL AIRCRAFT

    Directory of Open Access Journals (Sweden)

    2016-01-01

    Full Text Available Aircraft are high-tech engineering products which are characterized by a wide range of properties including the two most important groups that respectively characterize the efficiency and technical level.Improving the aircraft efficiency is an essential factor for air transport development, but the efficiency can not be fully describe the technical system, especially in forecasting and new technology requirements development. Aircraft de- signer must evaluate the prospects of a technical solution, but it’s not always possible to calculate the efficiency accuratelyat the design stage. The operator should be able to choose the most technically-advanced aircraft available in the market inorder not to let it grow obsolete quickly. This determines the need for non-economic evaluation of technical systems that can be done by assessment of their technical level.The technical level is a general index that includes a set of technical perfection indicators. Technical perfection is reflected in terms of material and energy intensity, in terms of ergonomics, safety, etc. and is achieved as a result of origi- nal design solutions, the use of new high-strength low-density materials, the introduction of advanced technological pro-cesses, calculation methods, verification, testing, etc.There is a tight connection between the product properties and its weight, because weight is the material reflection of these properties. Therefore, improvement of the product properties usually leads to an intense increase of its weight. To deal with this phenomenon is only possible with widely using scientific and technical progress results. In accordance with this, the technical perfection can be interpreted as a major component of quality that is created without the weight increase. This approach requires investment in research and testing new technical solutions.The method was developed to determine the technical level of civil long-haul aircraft which has been modified to

  15. Paramedics' non-technical skills: a literature review.

    Science.gov (United States)

    Shields, Allan; Flin, Rhona

    2013-05-01

    Healthcare organisations have started to examine the impact that the human worker has on patient safety. Adopting the Crew Resource Management (CRM) approach, used in aviation, the CRM or non-technical skills of anaesthetists, surgeons, scrub practitioners and emergency physicians have recently been identified to assist in their training and assessment. Paramedics are exposed to dynamic and dangerous situations where patients have to be managed, often with life-threatening injuries or illness. As in other safety-critical domains, the technical skills of paramedics are complemented by effective non-technical skills. The aim of this paper was to review the literature on the non-technical (social and cognitive) skills used by paramedics. This review was undertaken as part of a task analysis to identify the non-technical skills used by paramedics. Of the seven papers reviewed, the results have shown very little research on this topic and so reveal a gap in the understanding of paramedic non-technical skills.

  16. DRDC Toronto Technical Stream Integrated Capabilities and Vision

    Science.gov (United States)

    2011-09-01

    developed as part of this process: “To impact Defence and Security and enable the DRDC S&T program as technical leaders and integral partners.” iv...existantes : Expertise multidisciplinaire dans des domaines techniques et humains ; Expertise à l’égard de l’infrastructure ainsi que des...Technology for a Secure Canada (2006) DRDC Toronto TM 2011-017 3 integrated capabilities and the impact these contributions have towards

  17. Time-resolved fluorescence methods (IUPAC Technical Report)

    OpenAIRE

    Lemmetyinen, Helge; Tkachenko, Nikolai V.; Valeur, Bernard; Hotta, Jun-ichi; AMELOOT, Marcel; Ernsting, Nikolaus P.; Gustavsson, Thomas; Boens, Noel

    2014-01-01

    This IUPAC Technical Report describes and compares the currently applied methods for measuring and analyzing time-resolved fluorescence traces using phase-modulation fluorometry as well as pulse fluorometry (direct emission decay measurements, single-photon timing, streak camera measurements, fluorescence upconversion, and optical Kerr gating). The paper starts with a brief description of the basic principles for time and frequency domain fluorescence spectroscopy. The fundamental equations a...

  18. Topology Based Domain Search (TBDS)

    National Research Council Canada - National Science Library

    Manning, William

    2002-01-01

    This effort will explore radical changes in the way Domain Name System (DNS) is used by endpoints in a network to improve the resilience of the endpoint and its applications in the face of dynamically changing infrastructure topology...

  19. Heliborne time domain electromagnetic system

    International Nuclear Information System (INIS)

    Bhattacharya, S.

    2009-01-01

    Atomic Minerals Directorate (AMD), are using heliborne and ground time domain electromagnetic (TDEM) system for the exploration of deep seated unconformity type uranium deposits. Uranium has been explored in various parts of the world like Athabasca basin using time domain electromagnetic system. AMD has identified some areas in India where such deposits are available. Apart from uranium exploration, the TDEM systems are used for the exploration of deep seated minerals like diamonds. Bhabha Atomic Research Centre (BARC) is involved in the indigenous design of the heliborne time domain system since this system is useful for DAE and also it has a scope of wide application. In this paper we discuss about the principle of time domain electromagnetic systems, their capabilities and the development and problems of such system for various other mineral exploration. (author)

  20. Anisotropy of domain wall resistance

    Science.gov (United States)

    Viret; Samson; Warin; Marty; Ott; Sondergard; Klein; Fermon

    2000-10-30

    The resistive effect of domain walls in FePd films with perpendicular anisotropy was studied experimentally as a function of field and temperature. The films were grown directly on MgO substrates, which induces an unusual virgin magnetic configuration composed of 60 nm wide parallel stripe domains. This allowed us to carry out the first measurements of the anisotropy of domain wall resistivity in the two configurations of current perpendicular and parallel to the walls. At 18 K, we find 8.2% and 1.3% for the domain wall magnetoresistance normalized to the wall width (8 nm) in these two respective configurations. These values are consistent with the predictions of Levy and Zhang.

  1. Ferroelectric Negative Capacitance Domain Dynamics

    OpenAIRE

    Hoffmann, Michael; Khan, Asif Islam; Serrao, Claudy; Lu, Zhongyuan; Salahuddin, Sayeef; Pešić, Milan; Slesazeck, Stefan; Schroeder, Uwe; Mikolajick, Thomas

    2017-01-01

    Transient negative capacitance effects in epitaxial ferroelectric Pb(Zr$_{0.2}$Ti$_{0.8}$)O$_3$ capacitors are investigated with a focus on the dynamical switching behavior governed by domain nucleation and growth. Voltage pulses are applied to a series connection of the ferroelectric capacitor and a resistor to directly measure the ferroelectric negative capacitance during switching. A time-dependent Ginzburg-Landau approach is used to investigate the underlying domain dynamics. The transien...

  2. Fatou-Bieberbach domains in

    Science.gov (United States)

    Forstnerič, Franc; Wold, Erlend F.

    2015-10-01

    We construct Fatou-Bieberbach domains in for n>1 which contain a given compact set K and at the same time avoid a totally real affine subspace L of dimension < n, provided that K∪ L is polynomially convex. By using this result, we show that the domain for 1≤ k< n enjoys the basic Oka property with approximation for maps from any Stein manifold of dimension < n.

  3. Incompleteness in the finite domain

    Czech Academy of Sciences Publication Activity Database

    Pudlák, Pavel

    2017-01-01

    Roč. 23, č. 4 (2017), s. 405-441 ISSN 1079-8986 EU Projects: European Commission(XE) 339691 - FEALORA Institutional support: RVO:67985840 Keywords : finite domain Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 0.742, year: 2016 https://www.cambridge.org/core/journals/bulletin-of-symbolic-logic/article/incompleteness-in-the-finite-domain/D239B1761A73DCA534A4805A76D81C76

  4. Domain Walls with Strings Attached

    Energy Technology Data Exchange (ETDEWEB)

    Shmakova, Marina

    2001-08-20

    We have constructed a bulk and brane action of IIA theory which describes a pair of BPS domain walls on S{sub 1}/Z{sub 2}, with strings attached. The walls are given by two orientifold O8-planes with coincident D8-branes and F1-D0-strings are stretched between the walls. This static configuration satisfies all matching conditions for the string and domain wall sources and has 1/4 of unbroken supersymmetry.

  5. Incompleteness in the finite domain

    Czech Academy of Sciences Publication Activity Database

    Pudlák, Pavel

    2017-01-01

    Roč. 23, č. 4 (2017), s. 405-441 ISSN 1079-8986 EU Projects: European Commission(XE) 339691 - FEALORA Institutional support: RVO:67985840 Keywords : finite domain Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 0.742, year: 2016 https://www.cambridge.org/core/ journals /bulletin-of-symbolic-logic/article/incompleteness-in-the-finite-domain/D239B1761A73DCA534A4805A76D81C76

  6. Overview and status of ITER internal components

    International Nuclear Information System (INIS)

    Merola, Mario; Escourbiac, Frederic; Raffray, René; Chappuis, Philippe; Hirai, Takeshi; Martin, Alex

    2014-01-01

    Highlights: • Manufacturing technologies for the ITER internal components have been developed. • The Blanket System successfully went through its Final Design Review in April 2013. • The decision to start operation with a Divertor with a full-W armour has been taken. - Abstract: The internal components of ITER are one of the most design and technically challenging components of the ITER machine, and include the Blanket System and the Divertor. The Blanket System successfully went through its Final Design Review in April 2013 and now it is entering into the procurement phase. The design and qualification of the Divertor with a full-tungsten armour was successfully completed and this enabled the decision in November 2013 to start operation with this material option. This paper summarizes the engineering design, the R and D, the technology qualification and procurement status of the Blanket System and of the Divertor of the ITER machine

  7. Overview and status of ITER internal components

    Energy Technology Data Exchange (ETDEWEB)

    Merola, Mario, E-mail: mario.merola@iter.org; Escourbiac, Frederic; Raffray, René; Chappuis, Philippe; Hirai, Takeshi; Martin, Alex

    2014-10-15

    Highlights: • Manufacturing technologies for the ITER internal components have been developed. • The Blanket System successfully went through its Final Design Review in April 2013. • The decision to start operation with a Divertor with a full-W armour has been taken. - Abstract: The internal components of ITER are one of the most design and technically challenging components of the ITER machine, and include the Blanket System and the Divertor. The Blanket System successfully went through its Final Design Review in April 2013 and now it is entering into the procurement phase. The design and qualification of the Divertor with a full-tungsten armour was successfully completed and this enabled the decision in November 2013 to start operation with this material option. This paper summarizes the engineering design, the R and D, the technology qualification and procurement status of the Blanket System and of the Divertor of the ITER machine.

  8. Towards Cognitive Component Analysis

    DEFF Research Database (Denmark)

    Hansen, Lars Kai; Ahrendt, Peter; Larsen, Jan

    2005-01-01

    Cognitive component analysis (COCA) is here defined as the process of unsupervised grouping of data such that the ensuing group structure is well-aligned with that resulting from human cognitive activity. We have earlier demonstrated that independent components analysis is relevant for representi...

  9. Technical standards in the law of technical safety

    International Nuclear Information System (INIS)

    Marburger, P.

    1985-01-01

    Technical standards are of great importance for the closer definition of inexact terms of law, for instance ''generally accepted technical rules'', ''state of the art'', ''state of science and technology'' or similar normative terms, in the law of technical safety. The paper discusses with whom the authority for regulating this sector of law rests, deals with the different ways of how technical standards are used by the law (''anticipated expert opinion'', reference to such standards in law and administration) and points out demands on the procedure of standardization. (orig.) [de

  10. Technical Support Essentials Advice to Succeed in Technical Support

    CERN Document Server

    Sanchez, Andrew

    2010-01-01

    Technical Support Essentials is a book about the many facets of technical support. It attempts to provide a wide array of topics to serve as points of improvement, discussion, or simply topics that you might want to learn. The topics range from good work habits to the way technical supportgroups establish their own style of work. This book applies theories, models, and concepts synthesized from existing research in other fields-such as management, economics, leadership, and psychology-and connects them to technical support. The goal is to build on the work of others and allow their success to

  11. The Fermilab Main Injector Technical Design Handbook

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1994-08-01

    This report contains a description of the design, cost estimate, and construction schedule of the Fermilab Main Injector (FMI) Project. The technical, cost, and schedule baselines for the FMI Project have already been established and may be found in the Fermilab Main Injector Title I Design Report, issued in August 1992. This report updates and expands upon the design and schedule for construction of all subsystem components and associated civil construction described in the Title I Design Report. The facilities described have been designed in conformance with DOE 6430.1A, "United States Department of Energy General Design Criteria."

  12. Technical considerations in materials management policy development

    International Nuclear Information System (INIS)

    Avci, H.; Goldberg, M.

    1996-01-01

    Under the Materials-in-Inventory (MIN) initiative, US DOE intends to develop policies to ensure that materials are managed and use efficiently, cost-effectively, and safely throughout DOE. The MIN initiative covers depleted uranium, scrap metals, chemicals, explosives, spent nuclear fuel, lead, alkali metals, etc.; by far the largest component is depleted uranium hexafluoride (DUF6). A technically defensible approach has been developed and is being used to select a long-term management strategy for DOE's DUF6 inventory. The same approach can be adapted to management of other materials in inventory that have the potential to be reutilized

  13. Applying Standard Industrial Components for Active Magnetic Bearings

    Directory of Open Access Journals (Sweden)

    Bert-Uwe Koehler

    2017-02-01

    Full Text Available With the increasing number of active magnetic bearing applications, satisfying additional requirements is becoming increasingly more important. As for every technology, moving away from being a niche product and achieving a higher level of maturity, these requirements relate to robustness, reliability, availability, safety, security, traceability, certification, handling, flexibility, reporting, costs, and delivery times. Employing standard industrial components, such as those from flexible modular motion control drive systems, is an approach that allows these requirements to be satisfied while achieving rapid technological innovation. In this article, we discuss technical and non-technical aspects of using standard industrial components in magnetic bearing applications.

  14. Applications of Frequency Domain Curve-fitting in the EFDD Technique

    DEFF Research Database (Denmark)

    Jacobsen, Niels-Jørgen; Andersen, Palle; Brincker, Rune

    2008-01-01

    Over the years different methods have been proposed for how to deal with the presence of harmonic components in operational modal analysis. In this paper a method for detection of harmonic components using Fast Kurtosis Checking will be introduced along with a new frequency domain curve-fitting v......Over the years different methods have been proposed for how to deal with the presence of harmonic components in operational modal analysis. In this paper a method for detection of harmonic components using Fast Kurtosis Checking will be introduced along with a new frequency domain curve......-fitting version of the Enhanced Frequency Domain Decomposition (EFDD) technique. This combined approach makes it possible to extract structural modes fast even when several harmonic components are present and even when the harmonic components are located exactly at the natural frequencies of the structural modes...

  15. Tore Supra: technical description

    International Nuclear Information System (INIS)

    1985-08-01

    This report is aimed, after a brief recall of physics and technologic perspectives of Tore Supra, at giving a detailed description of the basic machine; details of each component are defined. Volume 1 is specifically concerned with the general aspects of Tore Supra and the toroidal field system [fr

  16. Effective Domain Partitioning for Multi-Clock Domain IP Core Wrapper Design under Power Constraints

    Science.gov (United States)

    Yu, Thomas Edison; Yoneda, Tomokazu; Zhao, Danella; Fujiwara, Hideo

    The rapid advancement of VLSI technology has made it possible for chip designers and manufacturers to embed the components of a whole system onto a single chip, called System-on-Chip or SoC. SoCs make use of pre-designed modules, called IP-cores, which provide faster design time and quicker time-to-market. Furthermore, SoCs that operate at multiple clock domains and very low power requirements are being utilized in the latest communications, networking and signal processing devices. As a result, the testing of SoCs and multi-clock domain embedded cores under power constraints has been rapidly gaining importance. In this research, a novel method for designing power-aware test wrappers for embedded cores with multiple clock domains is presented. By effectively partitioning the various clock domains, we are able to increase the solution space of possible test schedules for the core. Since previous methods were limited to concurrently testing all the clock domains, we effectively remove this limitation by making use of bandwidth conversion, multiple shift frequencies and properly gating the clock signals to control the shift activity of various core logic elements. The combination of the above techniques gains us greater flexibility when determining an optimal test schedule under very tight power constraints. Furthermore, since it is computationally intensive to search the entire expanded solution space for the possible test schedules, we propose a heuristic 3-D bin packing algorithm to determine the optimal wrapper architecture and test schedule while minimizing the test time under power and bandwidth constraints.

  17. Is Domain Highlighting Actually Helpful in Identifying Phishing Web Pages?

    Science.gov (United States)

    Xiong, Aiping; Proctor, Robert W; Yang, Weining; Li, Ninghui

    2017-06-01

    To evaluate the effectiveness of domain highlighting in helping users identify whether Web pages are legitimate or spurious. As a component of the URL, a domain name can be overlooked. Consequently, browsers highlight the domain name to help users identify which Web site they are visiting. Nevertheless, few studies have assessed the effectiveness of domain highlighting, and the only formal study confounded highlighting with instructions to look at the address bar. We conducted two phishing detection experiments. Experiment 1 was run online: Participants judged the legitimacy of Web pages in two phases. In Phase 1, participants were to judge the legitimacy based on any information on the Web page, whereas in Phase 2, they were to focus on the address bar. Whether the domain was highlighted was also varied. Experiment 2 was conducted similarly but with participants in a laboratory setting, which allowed tracking of fixations. Participants differentiated the legitimate and fraudulent Web pages better than chance. There was some benefit of attending to the address bar, but domain highlighting did not provide effective protection against phishing attacks. Analysis of eye-gaze fixation measures was in agreement with the task performance, but heat-map results revealed that participants' visual attention was attracted by the highlighted domains. Failure to detect many fraudulent Web pages even when the domain was highlighted implies that users lacked knowledge of Web page security cues or how to use those cues. Potential applications include development of phishing prevention training incorporating domain highlighting with other methods to help users identify phishing Web pages.

  18. On technical security issues in cloud computing

    DEFF Research Database (Denmark)

    Jensen, Meiko; Schwenk, Jörg; Gruschka, Nils

    2009-01-01

    The Cloud Computing concept offers dynamically scalable resources provisioned as a service over the Internet. Economic benefits are the main driver for the Cloud, since it promises the reduction of capital expenditure (CapEx) and operational expenditure (OpEx). In order for this to become reality......, however, there are still some challenges to be solved. Amongst these are security and trust issues, since the user's data has to be released to the Cloud and thus leaves the protection sphere of the data owner. Most of the discussions on this topics are mainly driven by arguments related to organisational...... means. This paper focusses on technical security issues arising from the usage of Cloud services and especially by the underlying technologies used to build these cross-domain Internet-connected collaborations....

  19. Technical Training Seminar

    CERN Multimedia

    2003-01-01

    Wednesday 19 November From 9:30 to 17:30 - IT Amphitheatre bldg.31 3-004 2003 Data Transmission Design Seminar - TEXAS INSTRUMENTS The one-day 2003 Data Transmission Design Seminar is part of a series of technical seminars produced by Texas Instruments. This series of seminars will introduce system solutions based on different standards according to their respective requirements. It will include topics containing a blend of basic principles and hands-on application examples, along with layout-guidelines. • Basics and Practical Examples of Data-Transmission • Low Voltage Differential Signaling (LVDS) • Connectivity and PC-based Links • Industrial Interfaces • Parallel Bus Systems and Clock-Distribution-Circuits (CDC) This Seminar will be of interest to hardware designers and system engineers dealing with the realization of system- or board-level interfaces based on various transmission standards. Language: English Free seminar, no registration Organiser: John ...

  20. Technical Math For Dummies

    CERN Document Server

    Schoenborn, Barry

    2010-01-01

    Technical Math For Dummies is your one-stop, hands-on guide to acing the math courses you’ll encounter as you work toward getting your degree, certifacation, or�license in the skilled trades. You’ll get easy-to-follow, plain-English guidance on mathematical formulas and methods that professionals use every day in the automotive, health, construction, licensed trades, maintenance, and other trades. You’ll learn how to apply concepts of algebra, geometry, and trigonometry and their formulas related to occupational areas of study. Plus, you’ll find out how to perform basic arithmetic

  1. Technical applications of aerogels

    International Nuclear Information System (INIS)

    Hrubesh, L.W.

    1997-01-01

    Aerogel materials posses such a wide variety of exceptional properties that a striking number of applications have developed for them. Many of the commercial applications of aerogels such as catalysts, thermal insulation, windows, and particle detectors are still under development and new application as have been publicized since the ISA4 Conference in 1994: e.g.; supercapacitors, insulation for heat storage in automobiles, electrodes for capacitive deionization, etc. More applications are evolving as the scientific and engineering community becomes familiar with the unusual and exceptional physical properties of aerogels, there are also scientific and technical application, as well. This paper discusses a variety of applications under development at Lawrence Livermore National Laboratory for which several types of aerogels are formed in custom sizes and shapes. Particular discussions will focus on the uses of aerogels for physics experiments which rely on the exceptional, sometimes unique, properties of aerogels

  2. Technical Training: ELEC-2005

    CERN Multimedia

    Davide Vitè

    2005-01-01

    ELEC-2005 - Electronics in High Energy Physics: Autumn Term (November-December 2005) ELEC-2005 is a new course series on modern electronics, given by CERN physicists and engineers within the framework of the 2005 Technical Training Programme, in an extended format of the ELEC-2002 course series. This new, comprehensive course series is designed for people who are not electronics specialists, for example physicists, engineers and technicians working at or visiting the laboratory, who use or will use electronics in their present or future activities, in particular in the context of the LHC accelerator and experiments. ELEC-2005 is composed of four Terms. The Winter (Introduction to electronics in HEP), Spring (Integrated circuits and VLSI technology for physics), and Summer (System electronics for physics: Issues) Terms already took place. The Autumn Term: Electronics applications in HEP experiments (November-December, 10 lectures) is now open for online registration, and will start on November 8th with the...

  3. Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Eggeman, Tim [ZeaChem Inc., Lakewood, CO (United States); O' Neill, Brian [ZeaChem Inc., Lakewood, CO (United States)

    2016-08-17

    ZeaChem Inc. and US DOE successfully demonstrated the ZeaChem process for producing sugars and ethanol from high-impact biomass feedstocks. The project was executed over a 5-year period under a $31.25 million cooperative agreement (80:20 Federal:ZeaChem cost share). The project was managed by dividing it into three budget periods. Activities during Budget Period 1 were limited to planning, permitting, and other pre-construction planning. Budget Period 2 activities included engineering, procurement, construction, commissioning, start-up and initial operations through the Independent Engineer Test Runs. The scope of construction was limited to the Chem Frac and Hydrogenolysis units, as the Core Facility was already in place. Construction was complete in December 2012, and the first cellulosic ethanol was produced in February 2013. Additional operational test runs were conducted during Budget Period 3 (completed June 2015) using hybrid poplar, corn stover, and wheat straw feedstocks, resulting in the production of cellulosic ethanol and various other biorefinery intermediates. The research adds to the understanding of the Chem Frac and Hydrogenolysis technologies in that the technical performance of each unit was measured, and the resulting data and operational experience can be used as the basis for engineering designs, thus mitigating risks for deployment in future commercial facilities. The Chem Frac unit was initially designed to be operated as two-stage dilute acid hydrolysis, with first stage conditions selected to remove the hemicellulose fraction of the feedstock, and the second stage conditions selected to remove the cellulose fraction. While the Chem Frac unit met or exceeded the design capacity of 10 ton(dry)/day, the technical effectiveness of the Chem Frac unit was below expectations in its initial two-stage dilute acid configuration. The sugars yields were low, the sugars were dilute, and the sugars had poor fermentability caused by excessive inhibitors

  4. Technical Report - FINAL

    Energy Technology Data Exchange (ETDEWEB)

    Barbara Luke, Director, UNLV Engineering Geophysics Laboratory

    2007-04-25

    Improve understanding of the earthquake hazard in the Las Vegas Valley and to assess the state of preparedness of the area's population and structures for the next big earthquake. 1. Enhance the seismic monitoring network in the Las Vegas Valley 2. Improve understanding of deep basin structure through active-source seismic refraction and reflection testing 3. Improve understanding of dynamic response of shallow sediments through seismic testing and correlations with lithology 4. Develop credible earthquake scenarios by laboratory and field studies, literature review and analyses 5. Refine ground motion expectations around the Las Vegas Valley through simulations 6. Assess current building standards in light of improved understanding of hazards 7. Perform risk assessment for structures and infrastructures, with emphasis on lifelines and critical structures 8. Encourage and facilitate broad and open technical interchange regarding earthquake safety in southern Nevada and efforts to inform citizens of earthquake hazards and mitigation opportunities

  5. ITER technical basis

    International Nuclear Information System (INIS)

    2002-01-01

    Following on from the Final Report of the EDA(DS/21), and the summary of the ITER Final Design report(DS/22), the technical basis gives further details of the design of ITER. It is in two parts. The first, the Plant Design specification, summarises the main constraints on the plant design and operation from the viewpoint of engineering and physics assumptions, compliance with safety regulations, and siting requirements and assumptions. The second, the Plant Description Document, describes the physics performance and engineering characteristics of the plant design, illustrates the potential operational consequences foe the locality of a generic site, gives the construction, commissioning, exploitation and decommissioning schedule, and reports the estimated lifetime costing based on data from the industry of the EDA parties

  6. Technical applications of aerogels

    Energy Technology Data Exchange (ETDEWEB)

    Hrubesh, L.W.

    1997-08-18

    Aerogel materials posses such a wide variety of exceptional properties that a striking number of applications have developed for them. Many of the commercial applications of aerogels such as catalysts, thermal insulation, windows, and particle detectors are still under development and new application as have been publicized since the ISA4 Conference in 1994: e.g.; supercapacitors, insulation for heat storage in automobiles, electrodes for capacitive deionization, etc. More applications are evolving as the scientific and engineering community becomes familiar with the unusual and exceptional physical properties of aerogels, there are also scientific and technical application, as well. This paper discusses a variety of applications under development at Lawrence Livermore National Laboratory for which several types of aerogels are formed in custom sizes and shapes. Particular discussions will focus on the uses of aerogels for physics experiments which rely on the exceptional, sometimes unique, properties of aerogels.

  7. LLNL 1981: technical horizons

    International Nuclear Information System (INIS)

    1981-07-01

    Research programs at LLNL for 1981 are described in broad terms. In his annual State of the Laboratory address, Director Roger Batzel projected a $481 million operating budget for fiscal year 1982, up nearly 13% from last year. In projects for the Department of Energy and the Department of Defense, the Laboratory applies its technical facilities and capabilities to nuclear weapons design and development and other areas of defense research that include inertial confinement fusion, nonnuclear ordnances, and particle-beam technology. LLNL is also applying its unique experience and capabilities to a variety of projects that will help the nation meet its energy needs in an environmentally acceptable manner. A sampling of recent achievements by LLNL support organizations indicates their diversity

  8. Mechanical Engineering Department Technical Review

    Energy Technology Data Exchange (ETDEWEB)

    Carr, R.B.; Denney, R.M. (eds.)

    1981-07-01

    The Mechanical Engineering Department Technical Review is published to inform readers of various technical activities within the Department, promote exchange of ideas, and give credit to personnel who are achieving the results. The report is presented in two parts: technical achievements and publication abstracts. The first is divided into seven sections, each of which reports on an engineering division and its specific activities related to nuclear tests, nuclear explosives, weapons, energy systems, engineering sciences, magnetic fusion, and materials fabrication.

  9. Mechanical engineering department technical review

    International Nuclear Information System (INIS)

    Carr, R.B.; Denney, R.M.

    1981-01-01

    The Mechanical Engineering Department Technical Review is published to: (1) inform the readers of various technical activities within the department, (2) promote exchange of ideas, and (3) give credit to the personnel who are achieving the results. The report is formatted into two parts: technical acievements and publication abstracts. The first is divided into eight sections, one for each division in the department providing the reader with the names of the personnel and the division accomplishing the work

  10. Mechanical Engineering Department. Technical review

    Energy Technology Data Exchange (ETDEWEB)

    Simecka, W.B.; Condouris, R.A.; Talaber, C. (eds.)

    1980-01-01

    The Mechanical Engineering Department Technical Review is published to (1) inform the readers of various technical activities within the Department, (2) promote exchange of ideas, and (3) give credit to the personnel who are achieving the results. The report is formatted into two parts: technical achievements and publication abstracts. The first is divided into eight sections, one for each Division in the Department providing the reader with the names of the personnel and the Division accomplishing the work.

  11. TECHNICAL CULTURE AND HUMAN AXJOSPHERE

    OpenAIRE

    ­Krystyna Chałas

    2014-01-01

    Technical culture is the value of each historical period. It is the subject of the ongoing development. While it is a value which is associated with different categories of values, mainly material, cognitive, social. Between culture and these three categories of values ​ there is a cognitive effect. Technical culture determines the quality of human axjosphere. The aim of this study is to show the relationships and dependencies between technical culture and the structures in which a person liv...

  12. Mechanical engineering department technical review

    Energy Technology Data Exchange (ETDEWEB)

    Carr, R.B. Denney, R.M. (eds.)

    1981-01-01

    The Mechanical Engineering Department Technical Review is published to: (1) inform the readers of various technical activities within the department, (2) promote exchange of ideas, and (3) give credit to the personnel who are achieving the results. The report is formatted into two parts: technical acievements and publication abstracts. The first is divided into eight sections, one for each division in the department providing the reader with the names of the personnel and the division accomplishing the work.

  13. Mechanical Engineering Department technical abstracts

    International Nuclear Information System (INIS)

    Denney, R.M.

    1982-01-01

    The Mechanical Engineering Department publishes listings of technical abstracts twice a year to inform readers of the broad range of technical activities in the Department, and to promote an exchange of ideas. Details of the work covered by an abstract may be obtained by contacting the author(s). Overall information about current activities of each of the Department's seven divisions precedes the technical abstracts

  14. Mechanical Engineering Department. Technical review

    International Nuclear Information System (INIS)

    Simecka, W.B.; Condouris, R.A.; Talaber, C.

    1980-01-01

    The Mechanical Engineering Department Technical Review is published to (1) inform the readers of various technical activities within the Department, (2) promote exchange of ideas, and (3) give credit to the personnel who are achieving the results. The report is formatted into two parts: technical achievements and publication abstracts. The first is divided into eight sections, one for each Division in the Department providing the reader with the names of the personnel and the Division accomplishing the work

  15. Mechanical Engineering Department Technical Review

    International Nuclear Information System (INIS)

    Carr, R.B.; Denney, R.M.

    1981-01-01

    The Mechanical Engineering Department Technical Review is published to inform readers of various technical activities within the Department, promote exchange of ideas, and give credit to personnel who are achieving the results. The report is presented in two parts: technical achievements and publication abstracts. The first is divided into seven sections, each of which reports on an engineering division and its specific activities related to nuclear tests, nuclear explosives, weapons, energy systems, engineering sciences, magnetic fusion, and materials fabrication

  16. Mechanical Engineering Department technical abstracts

    Energy Technology Data Exchange (ETDEWEB)

    Denney, R.M. (ed.)

    1982-07-01

    The Mechanical Engineering Department publishes listings of technical abstracts twice a year to inform readers of the broad range of technical activities in the Department, and to promote an exchange of ideas. Details of the work covered by an abstract may be obtained by contacting the author(s). Overall information about current activities of each of the Department's seven divisions precedes the technical abstracts.

  17. The story of technical cooperation

    International Nuclear Information System (INIS)

    Park, Yang Taek

    1989-09-01

    This book gives descriptions of technical cooperation, which is about why does technology transfer?, process of technology transfer with model, decisive cause and cooperation of technology transfer, cost and effect of technology transfer, historical experience of technology transfer, cases of technology transfer by field such as rubber tire, medicine and computer industry and automobile industry, technology transfer process and present condition of technical cooperation, and strategy for rising of technical cooperation : selection of technology for object of cooperation and development of human resources.

  18. GMES Space Component: Programme overview

    Science.gov (United States)

    Aschbacher, J.; Milagro-Perez, M. P.

    2012-04-01

    The European Union (EU) and the European Space Agency (ESA) have developed the Global Monitoring for Environment and Security (GMES) programme as Europe's answer to the vital need for joined-up data about our climate, environment and security. Through a unique combination of satellite, atmospheric and Earth-based monitoring systems, the initiative will provide new insight into the state of the land, sea and air, providing policymakers, scientists, businesses and the public with accurate and timely information. GMES capabilities include monitoring and forecasting of climatic change, flood risks, soil and coastal erosion, crop and fish resources, air pollution, greenhouse gases, iceberg distribution and snow cover, among others. To accomplish this, GMES has been divided into three main components: Space, In-situ and Services. The Space Component, led by ESA, comprises five types of new satellites called Sentinels that are being developed by ESA specifically to meet the needs of GMES, the first of which to be launched in 2013. These missions carry a range of technologies, such as radar and multi-spectral imaging instruments for land, ocean and atmospheric monitoring. In addition, access to data from the so-called Contributing Missions guarantees that European space infrastructure is fully used for GMES. An integrated Ground Segment ensures access to Sentinels and Contributing Missions data. The in-situ component, under the coordination of the European Environment Agency (EEA), is composed of atmospheric and Earth based monitoring systems, and based on established networks and programmes at European and international levels. The European Commission is in charge of implementing the services component of GMES and of leading GMES overall. GMES services, fed with data from the Space and In-situ components, will provide essential information in five main domains, atmosphere, ocean and land monitoring as well as emergency response and security. Climate change has been added

  19. Development of an evaluation method for the quality of NPP MCR operators' communication using Work Domain Analysis (WDA)

    International Nuclear Information System (INIS)

    Jang, Inseok; Park, Jinkyun; Seong, Poonghyun

    2011-01-01

    Research highlights: → No evaluation method is available for operators' communication quality in NPPs. → To model this evaluation method, the Work Domain Analysis (WDA) method was found. → This proposed method was applied to NPP MCR operators. → The quality of operators' communication can be evaluated with the propose method. - Abstract: The evolution of work demands has seen industrial evolution itself evolve into the computerization of these demands, making systems more complex. This field is now known as the Complex Socio-Technical System. As communication failures are problems associated with Complex Socio-Technical Systems, it has been discovered that communication failures are the cause of many incidents and accidents in various industries, including the nuclear, aerospace and railway industries. Despite the fact that there have been many studies on the severity of communication failures, there is no evaluation method for operators' communication quality in Nuclear Power Plants (NPPs). Therefore, the objectives of this study are to develop an evaluation method for the quality of NPP Main Control Room (MCR) operators' communication and to apply the proposed method to operators in a full-scope simulator. To develop the proposed method, the Work Domain Analysis (WDA) method is introduced. Several characteristics of WDA, including Abstraction Decomposition Space (ADS) and the diagonal of ADS are the important points in developing an evaluation method for the quality of NPP MCR operators' communication. In addition, to apply the proposed method, nine teams working in NPPs participated in a field simulation. The results of this evaluation reveal that operators' communication quality improved as a greater proportion of the components in the developed evaluation criteria were mentioned. Therefore, the proposed method could be useful for evaluating the communication quality in any complex system.

  20. Methodology for risk-based analysis of technical specifications

    International Nuclear Information System (INIS)

    Vesely, W.E.; Gaertner, J.P.; Wagner, D.P.

    1985-01-01

    Part of the effort by EPRI to apply probabilistic risk assessment methods and results to the solution of utility problems involves the investigation of methods for risk-based analysis of technical specifications. The culmination of this investigation is the SOCRATES computer code developed by Battelle's Columbus Laboratories to assist in the evaluation of technical specifications of nuclear power plants. The program is designed to use information found in PRAs to re-evaluate risk for changes in component allowed outage times (AOTs) and surveillance test intervals (STIs). The SOCRATES program is a unique and important tool for technical specification evaluations. The detailed component unavailability model allows a detailed analysis of AOT and STI contributions to risk. Explicit equations allow fast and inexpensive calculations. Because the code is designed to accept ranges of parameters and to save results of calculations that do not change during the analysis, sensitivity studies are efficiently performed and results are clearly displayed

  1. Domain Decomposition Solvers for Frequency-Domain Finite Element Equations

    KAUST Repository

    Copeland, Dylan

    2010-10-05

    The paper is devoted to fast iterative solvers for frequency-domain finite element equations approximating linear and nonlinear parabolic initial boundary value problems with time-harmonic excitations. Switching from the time domain to the frequency domain allows us to replace the expensive time-integration procedure by the solution of a simple linear elliptic system for the amplitudes belonging to the sine- and to the cosine-excitation or a large nonlinear elliptic system for the Fourier coefficients in the linear and nonlinear case, respectively. The fast solution of the corresponding linear and nonlinear system of finite element equations is crucial for the competitiveness of this method. © 2011 Springer-Verlag Berlin Heidelberg.

  2. An Algebro-Topological Description of Protein Domain Structure

    Science.gov (United States)

    Penner, Robert Clark; Knudsen, Michael; Wiuf, Carsten; Andersen, Jørgen Ellegaard

    2011-01-01

    The space of possible protein structures appears vast and continuous, and the relationship between primary, secondary and tertiary structure levels is complex. Protein structure comparison and classification is therefore a difficult but important task since structure is a determinant for molecular interaction and function. We introduce a novel mathematical abstraction based on geometric topology to describe protein domain structure. Using the locations of the backbone atoms and the hydrogen bonds, we build a combinatorial object – a so-called fatgraph. The description is discrete yet gives rise to a 2-dimensional mathematical surface. Thus, each protein domain corresponds to a particular mathematical surface with characteristic topological invariants, such as the genus (number of holes) and the number of boundary components. Both invariants are global fatgraph features reflecting the interconnectivity of the domain by hydrogen bonds. We introduce the notion of robust variables, that is variables that are robust towards minor changes in the structure/fatgraph, and show that the genus and the number of boundary components are robust. Further, we invesigate the distribution of different fatgraph variables and show how only four variables are capable of distinguishing different folds. We use local (secondary) and global (tertiary) fatgraph features to describe domain structures and illustrate that they are useful for classification of domains in CATH. In addition, we combine our method with two other methods thereby using primary, secondary, and tertiary structure information, and show that we can identify a large percentage of new and unclassified structures in CATH. PMID:21629687

  3. An Algebro-topological description of protein domain structure.

    Science.gov (United States)

    Penner, Robert Clark; Knudsen, Michael; Wiuf, Carsten; Andersen, Jørgen Ellegaard

    2011-01-01

    The space of possible protein structures appears vast and continuous, and the relationship between primary, secondary and tertiary structure levels is complex. Protein structure comparison and classification is therefore a difficult but important task since structure is a determinant for molecular interaction and function. We introduce a novel mathematical abstraction based on geometric topology to describe protein domain structure. Using the locations of the backbone atoms and the hydrogen bonds, we build a combinatorial object--a so-called fatgraph. The description is discrete yet gives rise to a 2-dimensional mathematical surface. Thus, each protein domain corresponds to a particular mathematical surface with characteristic topological invariants, such as the genus (number of holes) and the number of boundary components. Both invariants are global fatgraph features reflecting the interconnectivity of the domain by hydrogen bonds. We introduce the notion of robust variables, that is variables that are robust towards minor changes in the structure/fatgraph, and show that the genus and the number of boundary components are robust. Further, we investigate the distribution of different fatgraph variables and show how only four variables are capable of distinguishing different folds. We use local (secondary) and global (tertiary) fatgraph features to describe domain structures and illustrate that they are useful for classification of domains in CATH. In addition, we combine our method with two other methods thereby using primary, secondary, and tertiary structure information, and show that we can identify a large percentage of new and unclassified structures in CATH.

  4. The logic of Technical Standardisation

    DEFF Research Database (Denmark)

    Nedergaard, Peter

    In this paper technical standardisation is understood and explained in a model where economic analysis is coupled with an analysis of the political system as proposed in rational choice theory. The aim is to answer both the question why various countries (e.g. the United States versus European...... countries) let either the market or public intervention determine the mode of technical standardisation and the possible implications of these two ways of organizing technical standardisation from an economic and a political point of view. Based upon the analysis of the paper a couple of general policy...... recommendations are made concerning the mode of technical standardisation....

  5. Lessons Learned and Technical Standards: A Logical Marriage

    Science.gov (United States)

    Gill, Paul; Vaughan, William W.; Garcia, Danny; Gill, Maninderpal S. (Technical Monitor)

    2001-01-01

    A comprehensive database of lessons learned that corresponds with relevant technical standards would be a boon to technical personnel and standards developers. The authors discuss the emergence of one such database within NASA, and show how and why the incorporation of lessons learned into technical standards databases can be an indispensable tool for government and industry. Passed down from parent to child, teacher to pupil, and from senior to junior employees, lessons learned have been the basis for our accomplishments throughout the ages. Government and industry, too, have long recognized the need to systematically document And utilize the knowledge gained from past experiences in order to avoid the repetition of failures and mishaps. The use of lessons learned is a principle component of any organizational culture committed to continuous improvement. They have formed the foundation for discoveries, inventions, improvements, textbooks, and technical standards. Technical standards are a very logical way to communicate these lessons. Using the time-honored tradition of passing on lessons learned while utilizing the newest in information technology, the National Aeronautics and Space Administration (NASA) has launched an intensive effort to link lessons learned with specific technical standards through various Internet databases. This article will discuss the importance of lessons learned to engineers, the difficulty in finding relevant lessons learned while engaged in an engineering project, and the new NASA project that can help alleviate this difficulty. The article will conclude with recommendations for more expanded cross-sectoral uses of lessons learned with reference to technical standards.

  6. Stressing the Need for Safety in Technical Education

    Science.gov (United States)

    Defore, Jesse j.

    1974-01-01

    Discusses the importance of a safety orientation program in technical education and major components of a safety-conscious working enviroment. Suggests every institution take such measures as appointment of a safety officer, maintenance of a safety posture, inclusion of safety in curricula, and application of good safety practices. (CC)

  7. Facilitating Service Learning in the Online Technical Communication Classroom

    Science.gov (United States)

    Nielsen, Danielle

    2016-01-01

    Drawing from the author's experience teaching online technical communication courses with an embedded service-learning component, this essay opens the discussion to the potential problems involved in designing online service-learning courses and provides practical approaches to integrating service learning into online coursework. The essay…

  8. The Implications of Self-Reporting Systems for Maritime Domain Awareness

    National Research Council Canada - National Science Library

    Hammond, Tim; McIntyre, Mark; Chapman, David M; Lapinski, Anna-Liesa S

    2006-01-01

    Self-reporting systems based on GPS-quality navigation information that is sent using widely-accepted standards and protocols, offer the potential to greatly improve important components of Maritime Domain Awareness (MDA...

  9. Tiered Auctions for Multi-Agent Coordination in Domains with Precedence Constraints

    National Research Council Canada - National Science Library

    Jones, E. G; Dias, M. B; Stentz, Anthony

    2008-01-01

    .... Among these domains are some that require robots to interact closely at particular times and locations to accomplish some task components, but otherwise allow the team members to act independently...

  10. The Unknown Component Problem Theory and Applications

    CERN Document Server

    Villa, Tiziano; Brayton, Robert K; Mishchenko, Alan; Petrenko, Alexandre; Sangiovanni-Vincentelli, Alberto

    2012-01-01

    The Problem of the Unknown Component: Theory and Applications addresses the issue of designing a component that, combined with a known part of a system, conforms to an overall specification. The authors tackle this problem by solving abstract equations over a language. The most general solutions are studied when both synchronous and parallel composition operators are used. The abstract equations are specialized to languages associated with important classes of automata used for modeling systems. The book is a blend of theory and practice, which includes a description of a software package with applications to sequential synthesis of finite state machines. Specific topologies interconnecting the components, exact and heuristic techniques, and optimization scenarios are studied. Finally the scope is enlarged to domains like testing, supervisory control, game theory and synthesis for special omega languages. The authors present original results of the authors along with an overview of existing ones.

  11. Predictors of employer satisfaction: technical and non-technical skills.

    Science.gov (United States)

    Danielson, Jared A; Wu, Tsui-Feng; Fales-Williams, Amanda J; Kirk, Ryan A; Preast, Vanessa A

    2012-01-01

    Employers of 2007-2009 graduates from Iowa State University College of Veterinary Medicine were asked to respond to a survey regarding their overall satisfaction with their new employees as well as their new employees' preparation in several technical and non-technical skill areas. Seventy-five responses contained complete data and were used in the analysis. Four technical skill areas (data collection, data interpretation, planning, and taking action) and five non-technical skill areas (interpersonal skills, ability to deal with legal issues, business skills, making referrals, and problem solving) were identified. All of the skill area subscales listed above had appropriate reliability (Cronbach's alpha>0.70) and were positively and significantly correlated with overall employer satisfaction. Results of two simultaneous regression analyses indicated that of the four technical skill areas, taking action is the most salient predictor of employer satisfaction. Of the five non-technical skill areas, interpersonal skills, business skills, making referrals, and problem solving were the most important skills in predicting employer satisfaction. Hierarchical regression analysis revealed that all technical skills explained 25% of the variation in employer satisfaction; non-technical skills explained an additional 42% of the variation in employer satisfaction.

  12. Engineering the System and Technical Integration

    Science.gov (United States)

    Blair, J. C.; Ryan, R. S.; Schutzenhofer, L. A.

    2011-01-01

    Approximately 80% of the problems encountered in aerospace systems have been due to a breakdown in technical integration and/or systems engineering. One of the major challenges we face in designing, building, and operating space systems is: how is adequate integration achieved for the systems various functions, parts, and infrastructure? This Contractor Report (CR) deals with part of the problem of how we engineer the total system in order to achieve the best balanced design. We will discuss a key aspect of this question - the principle of Technical Integration and its components, along with management and decision making. The CR will first provide an introduction with a discussion of the Challenges in Space System Design and meeting the challenges. Next is an overview of Engineering the System including Technical Integration. Engineering the System is expanded to include key aspects of the Design Process, Lifecycle Considerations, etc. The basic information and figures used in this CR were presented in a NASA training program for Program and Project Managers Development (PPMD) in classes at Georgia Tech and at Marshall Space Flight Center (MSFC). Many of the principles and illustrations are extracted from the courses we teach for MSFC.

  13. Asymmetric cross-domain interference between two working memory tasks : Implications for models of working memory

    NARCIS (Netherlands)

    Morey, Candice C.; Morey, Richard D.; van der Reijden, Madeleine; Holweg, Margot

    2013-01-01

    Observations of higher dual-task costs for within-domain than cross-domain task combinations constitute classic evidence for multi-component models of working memory (e.g., Baddeley, 1986; Logie, 2011). However, we report an asymmetric pattern of interference between verbal and visual-spatial tasks,

  14. Crystallization and preliminary crystallographic characterization of an SH3 domain from the IB1 scaffold protein

    DEFF Research Database (Denmark)

    Dar, Imran; Bonny, Christophe; Pedersen, Jan Torleif

    2003-01-01

    IB1 is a mammalian scaffold protein that interacts with components of the c-Jun N-terminal kinase (JNK) signal-transduction pathway mainly via its protein-protein interaction domains. Crystallization of the key Src homology 3 (SH3) domain of IB1 has been achieved. Crystallization experiments with...

  15. Design of an online charging system to support IMS-based inter-domain composite services

    NARCIS (Netherlands)

    Le, M. van; Huitema, G.B.; Rumph, F.J.; Nieuwenhuis, L.J.M.; Beijnum, B.J.F. van

    2009-01-01

    For service providers online charging of composite services is necessary in order to manage financial risks of service delivery in multi-domain environments. At service level, inter-domain composite services consist of one or more service components, e.g. access service, IMS communication service or

  16. On the precision of an estimator of Mean for Domains in Double ...

    African Journals Online (AJOL)

    The results show that there is a positive contribution to the variance of the estimator which varies from one stratum to another. This addition vanishes where the domain coincides with a stratum. The total sampling variance depends only on components of variance for the domain and is inversely related to the total sample ...

  17. Towards a Domain Specific Software Architecture for Scientific Data Distribution

    Science.gov (United States)

    Wilson, A.; Lindholm, D. M.

    2011-12-01

    A reference architecture is a "design that satisfies a clearly distinguished subset of the functional capabilities identified in the reference requirements within the boundaries of certain design and implementation constraints, also identified in reference requirements." [Tracz, 1995] Recognizing the value of a reference architecture, NASA's ESDSWG's Standards Process Group (SPG) is introducing a multi-disciplinary science data systems (SDS) reference architecture in order to provide an implementation neutral, template solution for an architecture to support scientific data systems in general [Burnett, et al, 2011]. This reference architecture describes common features and patterns in scientific data systems, and can thus provide guidelines in building and improving such systems. But, guidelines alone may not be sufficient to actually build a system. A domain specific software architecture (DSSA) is "an assemblage of software components, specialized for a particular type of task (domain), generalized for effective use across that domain, composed in a standardized structure (topology) effective for building successful applications." [Tracz, 1995]. It can be thought of as relatively specific reference architecture. The "DSSA Process" is a software life cycle developed at Carnegie Melon's Software Engineering Institute that is based on the development and use of domain-specific software architectures, components, and tools. The process has four distinct activities: 1) develop a domain specific base/model, 2) populate and maintain the library, 3) build applications, 4) operate and maintain applications [Armitage, 1993]. The DSSA process may provide the missing link between guidelines and actual system construction. In this presentation we focus specifically on the realm of scientific data access and distribution. Assuming the role of domain experts in building data access systems, we report the results of creating a DSSA for scientific data distribution. We describe

  18. Explosive Components Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The 98,000 square foot Explosive Components Facility (ECF) is a state-of-the-art facility that provides a full-range of chemical, material, and performance analysis...

  19. Space laser components reliability

    OpenAIRE

    Riede, Wolfgang; Schroeder, Helmut

    2015-01-01

    Space environment presents unique challenges for operation of optics and optical coatings as part of laser systems. Besides testing components and sub-systems on the component qualification level, the extended testing of complete laser systems like flight modules under acceptance level conditions is an effective way to determine the reliability and long term stability, mitigating the mission risk. Hence, optics as part of high power space laser systems have to be extensively tested in view...

  20. Refractory alloy component fabrication

    International Nuclear Information System (INIS)

    Young, W.R.

    1984-01-01

    Purpose of this report is to describe joining procedures, primarily welding techniques, which were developed to construct reliable refractory alloy components and systems for advanced space power systems. Two systems, the Nb-1Zr Brayton Cycle Heat Receiver and the T-111 Alloy Potassium Boiler Development Program, are used to illustrate typical systems and components. Particular emphasis is given to specific problems which were eliminated during the development efforts. Finally, some thoughts on application of more recent joining technology are presented. 78 figures

  1. Component fragility research program

    International Nuclear Information System (INIS)

    Tsai, N.C.; Mochizuki, G.L.; Holman, G.S.

    1989-11-01

    To demonstrate how ''high-level'' qualification test data can be used to estimate the ultimate seismic capacity of nuclear power plant equipment, we assessed in detail various electrical components tested by the Pacific Gas ampersand Electric Company for its Diablo Canyon plant. As part of our Phase I Component Fragility Research Program, we evaluated seismic fragility for five Diablo Canyon components: medium-voltage (4kV) switchgear; safeguard relay board; emergency light battery pack; potential transformer; and station battery and racks. This report discusses our Phase II fragility evaluation of a single Westinghouse Type W motor control center column, a fan cooler motor controller, and three local starters at the Diablo Canyon nuclear power plant. These components were seismically qualified by means of biaxial random motion tests on a shaker table, and the test response spectra formed the basis for the estimate of the seismic capacity of the components. The seismic capacity of each component is referenced to the zero period acceleration (ZPA) and, in our Phase II study only, to the average spectral acceleration (ASA) of the motion at its base. For the motor control center, the seismic capacity was compared to the capacity of a Westinghouse Five-Star MCC subjected to actual fragility tests by LLNL during the Phase I Component Fragility Research Program, and to generic capacities developed by the Brookhaven National Laboratory for motor control center. Except for the medium-voltage switchgear, all of the components considered in both our Phase I and Phase II evaluations were qualified in their standard commercial configurations or with only relatively minor modifications such as top bracing of cabinets. 8 refs., 67 figs., 7 tabs

  2. Impact test of components

    International Nuclear Information System (INIS)

    Borsoi, L.; Buland, P.; Labbe, P.

    1987-01-01

    Stops with gaps are currently used to support components and piping: it is simple, low cost, efficient and permits free thermal expansion. In order to keep the nonlinear nature of stops, such design is often modeled by beam elements (for the component) and nonlinear springs (for the stops). This paper deals with the validity and the limits of these models through the comparison of computational and experimental results. The experimental results come from impact laboratory tests on a simplified mockup. (orig.)

  3. Lateral resonant Doppler flow measurement by spectral domain optical coherence tomography

    Science.gov (United States)

    Walther, Julia; Koch, Edmund

    2017-07-01

    In spectral domain optical coherence tomography (SD-OCT), any transverse motion component of a detected obliquely moving sample results in a nonlinear relationship between the Doppler phase shift and the axial sample velocity restricting phase-resolved Doppler OCT. To circumvent the limitation, we propose the lateral resonant Doppler flow quantification in spectral domain OCT, where the scanner movement velocity is matched to the transverse velocity component of the sample motion.

  4. Integral equation approach to time-dependent kinematic dynamos in finite domains

    International Nuclear Information System (INIS)

    Xu Mingtian; Stefani, Frank; Gerbeth, Gunter

    2004-01-01

    The homogeneous dynamo effect is at the root of cosmic magnetic field generation. With only a very few exceptions, the numerical treatment of homogeneous dynamos is carried out in the framework of the differential equation approach. The present paper tries to facilitate the use of integral equations in dynamo research. Apart from the pedagogical value to illustrate dynamo action within the well-known picture of the Biot-Savart law, the integral equation approach has a number of practical advantages. The first advantage is its proven numerical robustness and stability. The second and perhaps most important advantage is its applicability to dynamos in arbitrary geometries. The third advantage is its intimate connection to inverse problems relevant not only for dynamos but also for technical applications of magnetohydrodynamics. The paper provides the first general formulation and application of the integral equation approach to time-dependent kinematic dynamos, with stationary dynamo sources, in finite domains. The time dependence is restricted to the magnetic field, whereas the velocity or corresponding mean-field sources of dynamo action are supposed to be stationary. For the spherically symmetric α 2 dynamo model it is shown how the general formulation is reduced to a coupled system of two radial integral equations for the defining scalars of the poloidal and toroidal field components. The integral equation formulation for spherical dynamos with general stationary velocity fields is also derived. Two numerical examples - the α 2 dynamo model with radially varying α and the Bullard-Gellman model - illustrate the equivalence of the approach with the usual differential equation method. The main advantage of the method is exemplified by the treatment of an α 2 dynamo in rectangular domains

  5. Third International Mathematics and Science Study 1999 Video Study Technical Report: Volume 2--Science. Technical Report. NCES 2011-049

    Science.gov (United States)

    Garnier, Helen E.; Lemmens, Meike; Druker, Stephen L.; Roth, Kathleen J.

    2011-01-01

    This second volume of the Third International Mathematics and Science Study (TIMSS) 1999 Video Study Technical Report focuses on every aspect of the planning, implementation, processing, analysis, and reporting of the science components of the TIMSS 1999 Video Study. The report is intended to serve as a record of the actions and documentation of…

  6. TECHNICAL TRAINING SPECIAL SEMINAR

    CERN Multimedia

    Technical Training; Tel. 74924

    2001-01-01

    Wednesday 21 November From 9:00 hrs - bldg. 593 R-010 Linear Design Seminar James Bryant, Eberhard Brunner / ANALOG DEVICES Munich James Bryant, one of the well-known Analog Devices speakers, will present the reasons to use components based on new design processes. Among industrial and high speed applications, a particular focus will be given to single supply and low voltage applications. Eberhard Brunner is the specialist of RF products by Analog Devices. After several years in the US in the component design sector for these products, he will give a tutorial for communication and wireless, and applications based on high speed linear components. 09.00-10.15 Low voltage processes and high precision design techniques; AC and DC signal handling with low voltage and high speed products. 10.30-12.15 How to optimise high speed single supply applications; Single supply products in precision applications; Digital isolation, decoupling and grounding in high speed applications. 13.30-15.15 Communications and wireless, ...

  7. TECHNICAL TRAINING SPECIAL SEMINAR

    CERN Multimedia

    Technical Training; Tel.74924

    2001-01-01

    Wednesday 21 November From 9:00 hrs - Training Centre Auditorium room 11, bldg. 593 Linear Design Seminar James Bryant, Eberhard Brunner / ANALOG DEVICES Munich James Bryant, one of the well-known Analog Devices speakers, will present the reasons to use components based on new design processes. Among industrial and high speed applications, a particular focus will be given to single supply and low voltage applications. Eberhard Brunner is the specialist of RF products by Analog Devices. After several years in the US in the component design sector for these products, he will give a tutorial for communication and wireless, and applications based on high speed linear components. 09.00-10.15 Low voltage processes and high precision design techniques; AC and DC signal handling with low voltage and high speed products. 10.30-12.15 How to optimise high speed single supply applications; Single supply products in precision applications; Digital isolation, decoupling and grounding in high speed applications. 13.30-15.15...

  8. Domain specific MT in use

    DEFF Research Database (Denmark)

    Offersgaard, Lene; Povlsen, Claus; Almsten, Lisbeth Kjeldgaard

    2008-01-01

    point scale evaluate the sentence from the point of view of the post-editor. The post-editor profile defined by the LSP is based on the experiences of introducing MT in the LSP workflow. The relation between the Translation Edit Rate (TER) scores and “Usability” scores is tested. We find TER a candidate...... for an automatic metric simulating the post-editors’ usability judgements. LSP tests show 67% saved time in post-editing for the tested domain. Finally, the use of weighted sub-domain phrase tables in a SMT system is shown to improve translation quality.......The paper focuses on domain specific use of MT with a special focus on SMT in the workflow of a Language Service Provider (LSP). We report on the feedback of post-editors using fluency/adequacy evaluation and the evaluation metric ’Usability’, understood in this context as where users on a three...

  9. Angular Random Walk Estimation of a Time-Domain Switching Micromachined Gyroscope

    Science.gov (United States)

    2016-10-19

    TECHNICAL DOCUMENT 3308 September 2016 Angular Random Walk Estimation of a Time-Domain Switching Micromachined Gyroscope Andrew B. Sabater Paul...angular random walk (ARW), bias instability, and scale factor instability. While there are methods to address issues with bias and scale factor...8 4. ANGULAR RANDOM WALK CHARACTERIZATION

  10. Microcomputer Intelligence for Technical Training (MITT): The evolution of an intelligent tutoring system

    Science.gov (United States)

    Norton, Jeffrey E.; Wiederholt, Bradley J.; Johnson, William B.

    1990-01-01

    Microcomputer Intelligence for Technical Training (MITT) uses Intelligent Tutoring System (OTS) technology to deliver diagnostic training in a variety of complex technical domains. Over the past six years, MITT technology has been used to develop training systems for nuclear power plant diesel generator diagnosis, Space Shuttle fuel cell diagnosis, and message processing diagnosis for the Minuteman missile. Presented here is an overview of the MITT system, describing the evolution of the MITT software and the benefits of using the MITT system.

  11. COMPLEMENTARY EFFECTS IN ACTIVIZATION OF SCIENTIFIC AND TECHNICAL ACTIVITIES IN THE INFORMATION SOCIETY

    Directory of Open Access Journals (Sweden)

    O. Zhylinska

    2016-09-01

    Full Text Available This paper proposes new methodological approaches in the study of development problems of scientific and technical activities in the information society. The essence and economic nature of development scientific and technical activities' from the standpoint of methodological collectivism are disclosed, a new phenomenon intensification of development scientific and technical activities by forming the global networks of scientific and technical knowledge users that provides sharing of the burden of transformation and transaction costs as generation as well as economic implementation of research and technical knowledge across the globe are showed. This study outlines the complementary effects in intensify development of scientific and technological activities components: research and development (RD, training of scientific personnel, provision of scientific and technical services, which generates of world market's complementary goods, being world market of educational services of scientific and technical information, industrial properties, high technology products, venture capital investments and stock market.

  12. Career and Technical Education Teacher Shortage: A Successful Model for Recruitment and Retention

    Science.gov (United States)

    Wilkin, Thomas; Nwoke, Godfrey I.

    2011-01-01

    The role of Career and Technical Education (CTE) as a major source of skilled workers for the American economy and a vital component of American education is well established. Several recent studies show that when CTE programs combine rigorous academic standards and industry-based technical content, the result is higher academic achievement and…

  13. The Research on Analytical Method of Diquat Dibromide in Diquat Technical Concentrates

    Directory of Open Access Journals (Sweden)

    Gu Bing

    2016-01-01

    Full Text Available The technical concentrates (TK is prepared by technical material (TC, the content is lower than TC, it can be used for the preparation of pesticide formulations. Diquat TK is generally brown or dark brown liquid. In recent years, it develops rapidly as herbicides. This paper mainly introduces the research on analyses of the effective components in diquat TK.

  14. The Technical Report: An Analysis of Information Design and Packaging for an Inelastic Market.

    Science.gov (United States)

    Pinelli, Thomas E.; And Others

    As part of an evaluation of its scientific and technical information program, the National Aeronautics and Space Administration (NASA) conducted a review and analysis of structural, language, and presentation components of its technical report form. The investigation involved comparing and contrasting NASA's publications standards for technical…

  15. Agents unleashed a public domain look at agent technology

    CERN Document Server

    Wayner, Peter

    1995-01-01

    Agents Unleashed: A Public Domain Look at Agent Technology covers details of building a secure agent realm. The book discusses the technology for creating seamlessly integrated networks that allow programs to move from machine to machine without leaving a trail of havoc; as well as the technical details of how an agent will move through the network, prove its identity, and execute its code without endangering the host. The text also describes the organization of the host's work processing an agent; error messages, bad agent expulsion, and errors in XLISP-agents; and the simulators of errors, f

  16. Next Generation Nuclear Plant Project Technology Development Roadmaps: The Technical Path Forward

    Energy Technology Data Exchange (ETDEWEB)

    John Collins

    2009-01-01

    This document presents the Next Generation Nuclear Plant (NGNP) Systems, Subsystems, and Components, establishes a baseline for the current technology readiness status, and provides a path forward to achieve increasing levels of technical maturity.

  17. The logic of Technical Standardisation

    DEFF Research Database (Denmark)

    Nedergaard, Peter

    countries) let either the market or public intervention determine the mode of technical standardisation and the possible implications of these two ways of organizing technical standardisation from an economic and a political point of view. Based upon the analysis of the paper a couple of general policy...

  18. Technical Education and Economic Growth

    Indian Academy of Sciences (India)

    Technical Education and Economic Growth. Technical Education and Economic Growth. Review of the Present Status. Expanding no.s and impairment of quality; Faculty shortage; Grim situation ... Absence of International flavour. Consequences of Low Research. Some Success Stories. New Models of Institutional Structure ...

  19. The Digital technical documentation handbook

    CERN Document Server

    Schultz, Susan I; Kavanagh, Frank X; Morse, Marjorie J

    1993-01-01

    The Digital Technical Documentation Handbook describes the process of developing and producing technical user information at Digital Equipment Corporation. * Discusses techniques for making user information _more effective * Covers the draft and reviewprocess, the production and distribution of printed and electronic media, archiving, indexing, testing for usability, and many other topics * Provides quality assurance checklists, contains a glossary and a bibliography of resources for technicalcommunicators

  20. Aligning Career and Technical Education

    Science.gov (United States)

    Workman, Ed; Stubbs, Joyce

    2011-01-01

    The issues and concerns facing Kentucky Career and Technical Teacher Education (KY CTTE), university teacher educators and state department Career and Technical Education (CTE) leaders in providing and preparing the best CTE teachers possible are not unique to Kentucky. In an effort to better understand these issues and concerns a team of state…