WorldWideScience

Sample records for compact type iib

  1. TYPE IIb SUPERNOVAE WITH COMPACT AND EXTENDED PROGENITORS

    International Nuclear Information System (INIS)

    Chevalier, Roger A.; Soderberg, Alicia M.

    2010-01-01

    The classic example of a Type IIb supernova is SN 1993J, which had a cool extended progenitor surrounded by a dense wind. There is evidence for another category of Type IIb supernova that has a more compact progenitor with a lower density, probably fast, wind. Distinguishing features of the compact category are weak optical emission from the shock heated envelope at early times, nonexistent or very weak H emission in the late nebular phase, rapidly evolving radio emission, rapid expansion of the radio shell, and expected nonthermal as opposed to thermal X-ray emission. Type IIb supernovae that have one or more of these features include SNe 1996cb, 2001ig, 2003bg, 2008ax, and 2008bo. All of these with sufficient radio data (the last four) show evidence for presupernova wind variability. We estimate a progenitor envelope radius ∼1 x 10 11 cm for SN 2008ax, a value consistent with a compact Wolf-Rayet progenitor. Supernovae in the SN 1993J extended category include SN 2001gd and probably the Cas A supernova. We suggest that the compact Type IIb events be designated Type cIIb and the extended ones Type eIIb. The H envelope mass dividing these categories is ∼0.1 M sun .

  2. Type IIB flux vacua from G-theory I

    Energy Technology Data Exchange (ETDEWEB)

    Candelas, Philip [Mathematical Institute, University of Oxford,Andrew Wiles Building, Radcliffe Observatory Quarter,Woodstock Road, Oxford, OX2 6GG (United Kingdom); Constantin, Andrei [Department of Physics and Astronomy, Uppsala University,SE-751 20, Uppsala (Sweden); Damian, Cesar [Departamento de Fisica, DCI, Campus Leon, Universidad de Guanajuato,C.P. 37150, Leon, Guanajuato (Mexico); Larfors, Magdalena [Department of Physics and Astronomy, Uppsala University,SE-751 20, Uppsala (Sweden); Morales, Jose Francisco [INFN - Sezione di Roma “TorVergata”, Dipartimento di Fisica,Università di Roma “TorVergata”, Via della Ricerca Scientica, 00133 Roma (Italy)

    2015-02-27

    We construct non-perturbatively exact four-dimensional Minkowski vacua of type IIB string theory with non-trivial fluxes. These solutions are found by gluing together, consistently with U-duality, local solutions of type IIB supergravity on T{sup 4}×ℂ with the metric, dilaton and flux potentials varying along ℂ and the flux potentials oriented along T{sup 4}. We focus on solutions locally related via U-duality to non-compact Ricci-flat geometries. More general solutions and a complete analysis of the supersymmetry equations are presented in the companion paper http://arxiv.org/abs/1411.4786. We build a precise dictionary between fluxes in the global solutions and the geometry of an auxiliary K3 surface fibered over ℂℙ{sup 1}. In the spirit of F-theory, the flux potentials are expressed in terms of locally holomorphic functions that parametrize the complex structure moduli space of the K3 fiber in the auxiliary geometry. The brane content is inferred from the monodromy data around the degeneration points of the fiber.

  3. Type IIB flux vacua from G-theory I

    International Nuclear Information System (INIS)

    Candelas, Philip; Constantin, Andrei; Damian, Cesar; Larfors, Magdalena; Morales, Jose Francisco

    2015-01-01

    We construct non-perturbatively exact four-dimensional Minkowski vacua of type IIB string theory with non-trivial fluxes. These solutions are found by gluing together, consistently with U-duality, local solutions of type IIB supergravity on T"4×ℂ with the metric, dilaton and flux potentials varying along ℂ and the flux potentials oriented along T"4. We focus on solutions locally related via U-duality to non-compact Ricci-flat geometries. More general solutions and a complete analysis of the supersymmetry equations are presented in the companion paper http://arxiv.org/abs/1411.4786. We build a precise dictionary between fluxes in the global solutions and the geometry of an auxiliary K3 surface fibered over ℂℙ"1. In the spirit of F-theory, the flux potentials are expressed in terms of locally holomorphic functions that parametrize the complex structure moduli space of the K3 fiber in the auxiliary geometry. The brane content is inferred from the monodromy data around the degeneration points of the fiber.

  4. Canonical formulation of IIB D-branes

    International Nuclear Information System (INIS)

    Kamimura, K.

    1998-01-01

    We find Wess-Zumino actions for kappa invariant type IIB D-branes in explicit forms. A simple and compact expression is obtained by the use of spinor variables which are defined as power series of differential forms. Using the Wess-Zumino actions we develop the canonical formulation and find the complete set of the constraint equations for generic type IIB Dp-branes. The conserved global supersymmetry charges are determined and the algebra containing the central charges can be obtained explicitly. (orig.)

  5. Observation and interpretation of type IIb supernova explosions

    Science.gov (United States)

    Morales-Garoffolo, Antonia

    2016-03-01

    Core-collapse supernovae (CC-SNe) explosions represent the final demise of massive stars. Among the various types, there is a group of relatively infrequent CC-SNe termed type IIb, which appear to be hybrids between normal type II SNe (those characterised by H emission) and type Ib (those that lack H features in their spectra but exhibit prominent HeI lines). The nature of the stellar progenitors leading to type IIb SNe is currently unknown, although two channels are contemplated: single massive stars that have lost part of their outer envelope as a consequence of stellar winds, and massive stars that shed mass by Roche-Lobe overflow to a companion. The latter is in fact the favoured scenario for most of the objects observed up to now. In the majority of cases, when there are no direct progenitor detections, some hints about type IIb SN progenitors (e.g., initial mass) can be derived indirectly from the objects' light curves (LCs) and spectra. Motivated by the relatively few well-sampled observational datasets that exist up to date for type IIb SNe and the unknowns on their progenitors, we carried out extensive observations (mainly in the optical domain) for the young type IIb SNe 2011fu and 2013df. Both these SNe are particularly interesting because they show a first LC peak caused by shock breakout, followed by a secondary 56Ni-decay-powered maximum. The analysis of the data for SNe 2011fu and 2013df points to precursors that seem to have been stars with large radii (of the order of 100 RSun), with low mass hydrogen envelopes (tenths of MSun), and relatively low initial masses (12-18 MSun), which could have formed part of interacting binary systems. The nature of a third SN IIb candidate, OGLE-2013-SN-100, proved to be enigmatic. OGLE-2013-SN-100, shows a first peak in the LC, and other characteristics somewhat similar to those of type IIb SNe. However, after a deeper analysis, we conclude OGLE-2013-SN-100 is likely not a SN of type IIb. We provide an alternative

  6. New families of interpolating type IIB backgrounds

    Science.gov (United States)

    Minasian, Ruben; Petrini, Michela; Zaffaroni, Alberto

    2010-04-01

    We construct new families of interpolating two-parameter solutions of type IIB supergravity. These correspond to D3-D5 systems on non-compact six-dimensional manifolds which are mathbb{T}2 fibrations over Eguchi-Hanson and multi-center Taub-NUT spaces, respectively. One end of the interpolation corresponds to a solution with only D5 branes and vanishing NS three-form flux. A topology changing transition occurs at the other end, where the internal space becomes a direct product of the four-dimensional surface and the two-torus and the complexified NS-RR three-form flux becomes imaginary self-dual. Depending on the choice of the connections on the torus fibre, the interpolating family has either mathcal{N}=2 or mathcal{N}=1 supersymmetry. In the mathcal{N}=2 case it can be shown that the solutions are regular.

  7. GUTs on Compact Type IIB Orientifolds

    Energy Technology Data Exchange (ETDEWEB)

    Blumenhagen, Ralph; /Munich, Max Planck Inst.; Braun, Volker; /Dublin Inst.; Grimm, Thomas W.; /Bonn U.; Weigand, Timo; /SLAC

    2008-12-01

    We systematically analyze globally consistent SU(5) GUT models on intersecting D7-branes in genuine Calabi-Yau orientifolds with O3- and O7-planes. Beyond the well-known tadpole and K-theory cancellation conditions there exist a number of additional subtle but quite restrictive constraints. For the realization of SU(5) GUTs with gauge symmetry breaking via U(1)Y flux we present two classes of suitable Calabi-Yau manifolds defined via del Pezzo transitions of the elliptically fibred hypersurface P{sub 1,1,1,6,9}[18] and of the Quintic P{sub 1,1,1,1,1}[5], respectively. To define an orientifold projection we classify all involutions on del Pezzo surfaces. We work out the model building prospects of these geometries and present five globally consistent string GUT models in detail, including a 3-generation SU(5) model with no exotics whatsoever. We also realize other phenomenological features such as the 10 10 5{sub H} Yukawa coupling and comment on the possibility of moduli stabilization, where we find an entire new set of so-called swiss-cheese type Calabi-Yau manifolds. It is expected that both the general constrained structure and the concrete models lift to F-theory vacua on compact Calabi-Yau fourfolds.

  8. SEARCH FOR PRECURSOR ERUPTIONS AMONG TYPE IIB SUPERNOVAE

    Energy Technology Data Exchange (ETDEWEB)

    Strotjohann, Nora L.; Ofek, Eran O.; Gal-Yam, Avishay; Yaron, Ofer [Benoziyo Center for Astrophysics, Weizmann Institute of Science, 76100 Rehovot (Israel); Sullivan, Mark [School of Physics and Astronomy, University of Southampton, Southampton SO17 1BJ (United Kingdom); Kulkarni, Shrinivas R.; Cao, Yi [Cahill Center for Astronomy and Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Shaviv, Nir J. [School of Natural Sciences, Institute for Advanced Study, 1 Einstein Drive, Princeton, NJ 08540 (United States); Fremling, Christoffer; Sollerman, Jesper [The Oskar Klein Centre, Department of Astronomy, Stockholm University, AlbaNova, SE-10691 Stockholm (Sweden); Kasliwal, Mansi M. [Observatories of the Carnegie Institution for Science, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Nugent, Peter E. [Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720 (United States); Arcavi, Iair [Las Cumbres Observatory Global Telescope Network, 6740 Cortona Drive, Suite 102, Goleta, CA 93111 (United States); Filippenko, Alexei V. [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Laher, Russ; Surace, Jason [Spitzer Science Center, California Institute of Technology, M/S 314-6, Pasadena, CA 91125 (United States)

    2015-10-01

    The progenitor stars of several Type IIb supernovae (SNe) show indications of extended hydrogen envelopes. These envelopes might be the outcome of luminous energetic pre-explosion events, so-called precursor eruptions. We use the Palomar Transient Factory (PTF) pre-explosion observations of a sample of 27 nearby SNe IIb to look for such precursors during the final years prior to the SN explosion. No precursors are found when combining the observations in 15-day bins, and we calculate the absolute-magnitude-dependent upper limit on the precursor rate. At the 90% confidence level, SNe IIb have on average <0.86 precursors as bright as an absolute R-band magnitude of −14 in the final 3.5 years before the explosion and <0.56 events over the final year. In contrast, precursors among SNe IIn have a ≳5 times higher rate. The kinetic energy required to unbind a low-mass stellar envelope is comparable to the radiated energy of a few-weeks-long precursor that would be detectable for the closest SNe in our sample. Therefore, mass ejections, if they are common in such SNe, are radiatively inefficient or have durations longer than months. Indeed, when using 60-day bins, a faint precursor candidate is detected prior to SN 2012cs (∼2% false-alarm probability). We also report the detection of the progenitor of SN 2011dh that does not show detectable variability over the final two years before the explosion. The suggested progenitor of SN 2012P is still present, and hence is likely a compact star cluster or an unrelated object.

  9. Attractor horizons in six-dimensional type IIB supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Astefanesei, Dumitru, E-mail: dumitru.astefanesei@ucv.cl [Instituto de Fisica, Pontificia Universidad Catolica de Valparaiso, Casilla 4059, Valparaiso (Chile); Miskovic, Olivera, E-mail: olivera.miskovic@ucv.cl [Instituto de Fisica, Pontificia Universidad Catolica de Valparaiso, Casilla 4059, Valparaiso (Chile); Olea, Rodrigo, E-mail: rodrigo.olea@unab.cl [Universidad Andres Bello, Departamento de Ciencias Fisicas, Republica 220, Santiago (Chile)

    2012-08-14

    We consider near horizon geometries of extremal black holes in six-dimensional type IIB supergravity. In particular, we use the entropy function formalism to compute the charges and thermodynamic entropy of these solutions. We also comment on the role of attractor mechanism in understanding the entropy of the Hopf T-dual solutions in type IIA supergravity.

  10. Seven-branes and instantons in type IIB supergravity

    NARCIS (Netherlands)

    Hartong, Jelle

    2008-01-01

    F-theory provides a means to study the type IIB string theory in the non-perturbative regime where the complex coupling is of order unity. This should be contrasted with the perturbative regime where the string coupling is small. F-theory will be used in this thesis to argue for the existence of

  11. Supersymmetric AdS6 solutions of type IIB supergravity

    International Nuclear Information System (INIS)

    Kim, Hyojoong; Kim, Nakwoo; Suh, Minwoo

    2015-01-01

    We study the general requirement for supersymmetric AdS 6 solutions in type IIB supergravity. We employ the Killing spinor technique and study the differential and algebraic relations among various Killing spinor bilinears to find the canonical form of the solutions. Our result agrees precisely with the work of Apruzzi et al. (JHEP 1411:099, 2014), which used the pure spinor technique. Hoping to identify the geometry of the problem, we also computed four-dimensional theory through the dimensional reduction of type IIB supergravity on AdS 6 . This effective action is essentially a non-linear sigma model with five scalar fields parametrizing SL(3,ℝ)/SO(2,1), modified by a scalar potential and coupled to Einstein gravity in Euclidean signature. We argue that the scalar potential can be explained by a subgroup CSO(1,1,1) ⊂SL(3,ℝ) in a way analogous to gauged supergravity

  12. SN 2015as: a low-luminosity Type IIb supernova without an early light-curve peak

    Science.gov (United States)

    Gangopadhyay, Anjasha; Misra, Kuntal; Pastorello, A.; Sahu, D. K.; Tomasella, L.; Tartaglia, L.; Singh, Mridweeka; Dastidar, Raya; Srivastav, S.; Ochner, P.; Brown, Peter J.; Anupama, G. C.; Benetti, S.; Cappellaro, E.; Kumar, Brajesh; Kumar, Brijesh; Pandey, S. B.

    2018-05-01

    We present results of the photometric (from 3 to 509 d post-explosion) and spectroscopic (up to 230 d post-explosion) monitoring campaign of the He-rich Type IIb supernova (SN) 2015as. The (B - V) colour evolution of SN 2015as closely resemble those of SN 2008ax, suggesting that SN 2015as belongs to the SN IIb subgroup that does not show the early, short-duration photometric peak. The light curve of SN 2015as reaches the B-band maximum about 22 d after the explosion, at an absolute magnitude of -16.82 ± 0.18 mag. At ˜75 d after the explosion, its spectrum transitions from that of a SN II to a SN Ib. P Cygni features due to He I lines appear at around 30 d after explosion, indicating that the progenitor of SN 2015as was partially stripped. For SN 2015as, we estimate a 56Ni mass of ˜0.08 M⊙ and ejecta mass of 1.1-2.2 M⊙, which are similar to the values inferred for SN 2008ax. The quasi-bolometric analytical light-curve modelling suggests that the progenitor of SN 2015as has a modest mass (˜0.1 M⊙), a nearly compact (˜0.05 × 1013 cm) H envelope on top of a dense, compact (˜2 × 1011 cm) and a more massive (˜1.2 M⊙) He core. The analysis of the nebular phase spectra indicates that ˜0.44 M⊙ of O is ejected in the explosion. The intensity ratio of the [Ca II]/[O I] nebular lines favours either a main-sequence progenitor mass of ˜15 M⊙ or a Wolf-Rayet star of 20 M⊙.

  13. Focal cortical dysplasia type IIa and IIb: MRI aspects in 118 cases proven by histopathology

    Energy Technology Data Exchange (ETDEWEB)

    Colombo, Nadia; Citterio, Alberto [Ospedale Ca Granda Niguarda, Department of Neuroradiology, Milano (Italy); Tassi, Laura; Mai, Roberto; Sartori, Ivana; Cardinale, Francesco; Lo Russo, Giorgio [Ospedale Niguarda, Claudio Munari Epilepsy Surgery Center, Milano (Italy); Deleo, Francesco; Spreafico, Roberto [IRCCS Foundation Neurological Institute ' ' C. Besta' ' , Department of Epilepsy Clinic and Experimental Neurophysiology, Milano (Italy); Bramerio, Manuela [Ospedale Niguarda, Department of Pathology, Milano (Italy)

    2012-10-15

    This study aims to review the magnetic resonance imaging (MRI) aspects of a large series of patients with focal cortical dysplasia type II (FCD II) and attempt to identify distinctive features in the two histopathological subtypes IIa and IIb. We retrospectively reviewed the MRI scans of 118 patients with histological proven FCD IIa (n = 37) or IIb (n = 81) who were surgically treated for intractable epilepsy. MRI was abnormal in 93 patients (79 %) and unremarkable in 25 (21 %). A dysplastic lesion was identified in 90 cases (97 %) and classified as FCD II in 83 and FCD non-II in seven cases. In three cases, the MRI diagnosis was other than FCD. There was a significant association between the presence of cortical thickening (p = 0.002) and the ''transmantle sign'' (p < 0.001) and a correct MRI diagnosis of FCD II. MRI positivity was more frequent in the patients with FCD IIb than in those with FCD IIa (91 % vs. 51 %), and the detection rate of FCD II was also better in the patients with type IIb (88 % vs. 32 %). The transmantle sign was significantly more frequent in the IIb subgroup (p = 0.003). The rates of abnormal MRI results and correct MRI diagnoses of FCD II were significantly higher in the IIb subgroup. Although other MRI stigmata may contribute to the diagnosis, the only significant correlation was between the transmantle sign and FCD IIb. (orig.)

  14. Altered inhibition in Tuberous Sclerosis and Type IIb cortical dysplasia

    Science.gov (United States)

    Talos, Delia M.; Sun, Hongyu; Kosaras, Bela; Joseph, Annelise; Folkerth, Rebecca D.; Poduri, Annapurna; Madsen, Joseph R.; Black, Peter M.; Jensen, Frances E.

    2012-01-01

    Objective The most common neurological symptom of tuberous sclerosis complex (TSC) and focal cortical dysplasia (FCD) is early-life refractory epilepsy. As previous studies have shown enhanced excitatory glutamatergic neurotransmission in TSC and FCD brains, we hypothesized that neurons associated with these lesions may also express altered GABAA receptor (GABAAR)-mediated inhibition. Methods Expression of the GABAAR subunitsα1 and α4, the Na+-K+-2Cl− (NKCC1), and the K+−Cl− (KCC2) transporters in human TSC and FCD Type II specimens were analyzed by Western blot and double label immunocytochemistry. GABAAR responses in dysplastic neurons from a single case of TSC were measured by perforated-patch recording and compared to normal-appearing cortical neurons from a non-TSC epilepsy case. Results TSC and FCD Type IIb lesions demonstrated decreased expression of the GABAAR α1, increased NKCC1 and decreased KCC2 levels. In contrast, FCD Type IIa lesions showed decreased α4, and increased expression of both NKCC1 and KCC2 transporters. Patch clamp recordings from dysplastic neurons in acute slices from TSC tubers demonstrated excitatory GABAAR responses that were significantly attenuated by the NKCC1 inhibitor bumetanide, in contrast to hyperpolarizing GABAAR-mediated currents in normal neurons from non-TSC cortical slices. Interpretation Expression and function of GABAARs in TSC and FCD IIb suggests the relative benzodiazepine insensitivity and more excitatory action of GABA compared to FCD IIa. These factors may contribute to resistance of seizure activity to anticonvulsants that increase GABAergic function, and may justify add-on trials of the NKCC1 inhibitor bumetanide for the treatment of TSC and FCD Type IIb related epilepsy. PMID:22447678

  15. On zero-point energy, stability and Hagedorn behavior of Type IIB strings on pp-waves

    International Nuclear Information System (INIS)

    Bigazzi, F.; Cotrone, A.L.

    2003-06-01

    Type IIB strings on many pp-wave backgrounds, supported either by 5-form or 3-form fluxes, have negative light-cone zero-point energy. This raises the question of their stability and poses possible problems in the definition of their thermodynamic properties. After having pointed out the correct way of calculating the zero-point energy, an issue not fully discussed in literature, we show that these Type IIB strings are classically stable and have well defined thermal properties, exhibiting a Hagedorn behavior. (author)

  16. Systematics of IIB spinorial geometry

    OpenAIRE

    Gran, U.; Gutowski, J.; Papadopoulos, G.; Roest, D.

    2005-01-01

    We reduce the classification of all supersymmetric backgrounds of IIB supergravity to the evaluation of the Killing spinor equations and their integrability conditions, which contain the field equations, on five types of spinors. This extends the work of [hep-th/0503046] to IIB supergravity. We give the expressions of the Killing spinor equations on all five types of spinors. In this way, the Killing spinor equations become a linear system for the fluxes, geometry and spacetime derivatives of...

  17. A sufficient condition for de Sitter vacua in type IIB string theory

    Energy Technology Data Exchange (ETDEWEB)

    Rummel, Markus [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Westphal, Alexander [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2011-07-15

    We derive a sufficient condition for realizing meta-stable de Sitter vacua with small positive cosmological constant within type IIB string theory flux compactifications with spontaneously broken supersymmetry. There are a number of 'lamp post' constructions of de Sitter vacua in type IIB string theory and supergravity. We show that one of them - the method of 'Kaehler uplifting' by F-terms from an interplay between non-perturbative effects and the leading {alpha}'-correction - allows for a more general parametric understanding of the existence of de Sitter vacua. The result is a condition on the values of the flux induced superpotential and the topological data of the Calabi-Yau compactification, which guarantees the existence of a meta-stable de Sitter vacuum if met. Our analysis explicitly includes the stabilization of all moduli, i.e. the Kaehler, dilaton and complex structure moduli, by the interplay of the leading perturbative and non-perturbative effects at parametrically large volume. (orig.)

  18. COMPARISON OF DIVERSITY OF TYPE IIB SUPERNOVAE WITH ASYMMETRY IN CASSIOPEIA A USING LIGHT ECHOES

    Energy Technology Data Exchange (ETDEWEB)

    Finn, Kieran; Bianco, Federica B.; Modjaz, Maryam; Liu, Yu-Qian [Center for Cosmology and Particle Physics, New York University, New York, NY 10003 (United States); Rest, Armin [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States)

    2016-10-20

    We compare the diversity of spectral line velocities in a large sample of type IIb supernovae (SNe IIb) with the expected asphericity in the explosion, as measured from the light echoes (LEs) of Cassiopeia A (Cas A), which was a historical galactic SN IIb. We revisit the results of Rest et al., who used LEs to observe Cas A from multiple lines of sight and hence determine its asphericity, as seen in the velocity of three spectral lines (He i λ 5876, H α , and the Ca ii near-infrared (NIR) triplet). We confirm and improve on this measurement by reproducing the effect of the LEs in the spectra of several extragalactic SNe IIb found in the literature as well as mean SN IIb spectra recently created by Liu et al. and comparing these to the observed light echo spectra of Cas A, including their associated uncertainties. In order to quantify the accuracy of this comparison, we smooth the light echo spectra of Cas A using Gaussian processes and use a Monte Carlo method to measure the absorption velocities of these three features in the spectra. We then test the hypothesis that the diversity of ejecta velocities seen in SNe IIb can be explained by asphericity. We do this by comparing the range of velocities seen in the different LEs, and hence different lines of sight, of Cas A to that seen in the population of SNe IIb. We conclude that these two ranges are of the same order and thus asphericity could be enough to explain the diversity in the expansion velocity alone.

  19. Importance of high-density lipoprotein cholesterol levels in elderly diabetic individuals with type IIb dyslipidemia: A 2-year survey of cardiovascular events.

    Science.gov (United States)

    Ina, Koichiro; Hayashi, Toshio; Araki, Atsushi; Kawashima, Seinosuke; Sone, Hirohito; Watanabe, Hiroshi; Ohrui, Takashi; Yokote, Koutaro; Takemoto, Minoru; Kubota, Kiyoshi; Noda, Mitsuhiko; Noto, Hiroshi; Ding, Qun-Fang; Zhang, Jie; Yu, Ze-Yun; Yoon, Byung-Koo; Nomura, Hideki; Kuzuya, Masafumi

    2014-10-01

    The risk factors for ischemic heart disease (IHD) or cerebrovascular accident (CVA) in elderly diabetic individuals with type IIb dyslipidemia are not fully known. Therefore, we investigated the relationship between lipid levels and IHD and CVA in diabetic individuals with type IIb dyslipidemia. The Japan Cholesterol and Diabetes Mellitus Study is a prospective cohort study of 4014 type 2 diabetic patients (1936 women; age 67.4 ± 9.5 years). The primary end-points were the onset of IHD or CVA. Lipid and glucose levels, and other factors were investigated in relation to the occurrence of IHD or CVA. A total of 462 participants were included in the group of patients with type IIb dyslipidemia. The 462 diabetic participants with type IIb dyslipidemia were divided into those who were aged 75 years (n=168, 190 and 104, respectively). High-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol/HDL-C were significantly associated with the risk of cardiovascular events in diabetic individuals with type IIb dyslipidemia who were aged dyslipidemia who were aged dyslipidemia who were aged <75 years. © 2013 Japan Geriatrics Society.

  20. Long-lasting X-ray emission from type IIb supernova 2011dh and mass-loss history of the yellow supergiant progenitor

    Energy Technology Data Exchange (ETDEWEB)

    Maeda, Keiichi [Department of Astronomy, Kyoto University, Kitashirakawa-Oiwake-cho, Sakyo-ku, Kyoto 606-8502 (Japan); Katsuda, Satoru [RIKEN (The Institute of Physical and Chemical Research) Nishina Center, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Bamba, Aya [Department of Physics and Mathematics, Aoyama Gakuin University, 5-10-1 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5258 (Japan); Terada, Yukikatsu [Graduate School of Science and Engineering, Saitama University, Shimo-Okubo 255, Sakura, Saitama 338-8570 (Japan); Fukazawa, Yasushi, E-mail: keiichi.maeda@kusastro.kyoto-u.ac.jp [Department of Physical Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8526 (Japan)

    2014-04-20

    Type IIb supernova (SN) 2011dh, with conclusive detection of an unprecedented yellow supergiant (YSG) progenitor, provides an excellent opportunity to deepen our understanding on the massive star evolution in the final centuries toward the SN explosion. In this paper, we report on detection and analyses of thermal X-ray emission from SN IIb 2011dh at ∼500 days after the explosion on Chandra archival data, providing a solidly derived mass-loss rate of a YSG progenitor for the first time. We find that the circumstellar media should be dense, more than that expected from a Wolf-Rayet (W-R) star by one order of magnitude. The emission is powered by a reverse shock penetrating into an outer envelope, fully consistent with the YSG progenitor but not with a W-R progenitor. The density distribution at the outermost ejecta is much steeper than that expected from a compact W-R star, and this finding must be taken into account in modeling the early UV/optical emission from SNe IIb. The derived mass-loss rate is ∼3 × 10{sup –6} M {sub ☉} yr{sup –1} for the mass-loss velocity of ∼20 km s{sup –1} in the final ∼1300 yr before the explosion. The derived mass-loss properties are largely consistent with the standard wind mass-loss expected for a giant star. This is not sufficient to be a main driver to expel nearly all the hydrogen envelope. Therefore, the binary interaction, with a huge mass transfer having taken place at ≳ 1300 yr before the explosion, is a likely scenario to produce the YSG progenitor.

  1. Schroedinger invariant solutions of type IIB with enhanced supersymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Donos, Aristomenis [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Gauntlett, Jerome P. [Imperial College, London (United Kingdom). Theoretical Physics Group; Imperial College, London (United Kingdom). Inst. for Mathematical Sciences

    2009-07-15

    We construct the Killing spinors for a class of supersymmetric solutions of type IIB supergravity that are invariant under the non-relativistic Schroedinger algebra. The solutions depend on a five-dimensional Sasaki- Einstein space and it has been shown that they admit two Killing spinors. Here we will show that, for generic Sasaki-Einstein space, there are special subclasses of solutions which admit six Killing spinors and we determine the corresponding superisometry algebra. We also show that for the special case that the Sasaki-Einstein space is the round five-sphere, the number of Killing spinors can be increased to twelve. (orig.)

  2. Ultraviolet Detection of the Binary Companion to the Type IIb SN 2001ig

    Science.gov (United States)

    Ryder, Stuart D.; Van Dyk, Schuyler D.; Fox, Ori D.; Zapartas, Emmanouil; de Mink, Selma E.; Smith, Nathan; Brunsden, Emily; Azalee Bostroem, K.; Filippenko, Alexei V.; Shivvers, Isaac; Zheng, WeiKang

    2018-03-01

    We present HST/WFC3 ultraviolet imaging in the F275W and F336W bands of the Type IIb SN 2001ig at an age of more than 14 years. A clear point source is detected at the site of the explosion, with m F275W = 25.39 ± 0.10 and m F336W = 25.88 ± 0.13 mag. Despite weak constraints on both the distance to the host galaxy NGC 7424 and the line-of-sight reddening to the supernova, this source matches the characteristics of an early B-type main-sequence star with 19,000 GMOS optical spectrum at an age of 6 years reveals a narrow He II λ4686 emission line, indicative of continuing interaction with a dense circumstellar medium at large radii from the progenitor. We review our findings on SN 2001ig in the context of binary evolution channels for stripped-envelope supernovae. Owing to the uncrowded nature of its environment in the ultraviolet, this study of SN 2001ig represents one of the cleanest detections to date of a surviving binary companion to a Type IIb supernova.

  3. On running couplings in gauge theories from type-IIB supergravity

    CERN Document Server

    Kehagias, A A

    1999-01-01

    We construct an explicit solution of type-IIB supergravity describing the strong coupling regime of a non-supersymmetric gauge theory. The latter has a running coupling with an ultraviolet stable fixed point corresponding to the N=4 SU(N) super-Yang-Mills theory at large N. The running coupling has a power law behaviour, argued to be universal, that is consistent with holography. Around the critical point, our solution defines an asymptotic expansion for the gauge coupling beta-function. We also calculate the first correction to the Coulombic quark-antiquark potential.

  4. Vertex operators of ghost number three in Type IIB supergravity

    International Nuclear Information System (INIS)

    Mikhailov, Andrei

    2016-01-01

    We study the cohomology of the massless BRST complex of the Type IIB pure spinor superstring in flat space. In particular, we find that the cohomology at the ghost number three is nontrivial and transforms in the same representation of the supersymmetry algebra as the solutions of the linearized classical supergravity equations. Modulo some finite dimensional spaces, the ghost number three cohomology is the same as the ghost number two cohomology. We also comment on the difference between the naive and semi-relative cohomology, and the role of b-ghost.

  5. The N=1 effective actions of D-branes in Type IIA and IIB orientifolds

    International Nuclear Information System (INIS)

    Grimm, Thomas W.; Vieira Lopes, Daniel

    2012-01-01

    We discuss the four-dimensional N=1 effective actions of single space-time filling Dp-branes in general Type IIA and Type IIB Calabi-Yau orientifold compactifications. The effective actions depend on an infinite number of normal deformations and gauge connection modes. For D6-branes the N=1 Kähler potential, the gauge-coupling function, the superpotential and the D-terms are determined as functions of these fields. They can be expressed as integrals over chains which end on the D-brane cycle and a reference cycle. The infinite deformation space will reduce to a finite dimensional moduli space of special Lagrangian submanifolds upon imposing F- and D-term supersymmetry conditions. We show that the Type IIA moduli space geometry is captured by three real functionals encoding the deformations of special Lagrangian submanifolds, holomorphic three-forms and Kähler two-forms of Calabi-Yau manifolds. These elegantly combine in the N=1 Kähler potential, which reduces after applying mirror symmetry to the results previously determined for space-time filling D3-, D5- and D7-branes. We also propose general chain integral expressions for the Kähler potentials of Type IIB D-branes.

  6. MULTI-WAVELENGTH OBSERVATIONS OF SUPERNOVA 2011ei: TIME-DEPENDENT CLASSIFICATION OF TYPE IIb AND Ib SUPERNOVAE AND IMPLICATIONS FOR THEIR PROGENITORS

    International Nuclear Information System (INIS)

    Milisavljevic, Dan; Margutti, Raffaella; Soderberg, Alicia M.; Chomiuk, Laura; Sanders, Nathan E.; Pignata, Giuliano; Bufano, Filomena; Fesen, Robert A.; Parrent, Jerod T.; Parker, Stuart; Mazzali, Paolo; Pian, Elena; Pickering, Timothy; Buckley, David A. H.; Crawford, Steven M.; Gulbis, Amanda A. S.; Hettlage, Christian; Hooper, Eric; Nordsieck, Kenneth H.; O'Donoghue, Darragh

    2013-01-01

    We present X-ray, UV/optical, and radio observations of the stripped-envelope, core-collapse supernova (SN) 2011ei, one of the least luminous SNe IIb or Ib observed to date. Our observations begin with a discovery within ∼1 day of explosion and span several months afterward. Early optical spectra exhibit broad, Type II-like hydrogen Balmer profiles that subside rapidly and are replaced by Type Ib-like He-rich features on a timescale of one week. High-cadence monitoring of this transition suggests absorption attributable to a high-velocity (∼> 12, 000 km s –1 ) H-rich shell, which is likely present in many Type Ib events. Radio observations imply a shock velocity of v ≈ 0.13 c and a progenitor star average mass-loss rate of M-dot ∼1.4×10 -5 M sun yr -1 (assuming wind velocity v w = 10 3 km s –1 ). This is consistent with independent constraints from deep X-ray observations with Swift-XRT and Chandra. Overall, the multi-wavelength properties of SN 2011ei are consistent with the explosion of a lower-mass (3-4 M ☉ ), compact (R * ∼ 11 cm), He-core star. The star retained a thin hydrogen envelope at the time of explosion, and was embedded in an inhomogeneous circumstellar wind suggestive of modest episodic mass loss. We conclude that SN 2011ei's rapid spectral metamorphosis is indicative of time-dependent classifications that bias estimates of the relative explosion rates for Type IIb and Ib objects, and that important information about a progenitor star's evolutionary state and mass loss immediately prior to SN explosion can be inferred from timely multi-wavelength observations.

  7. MULTI-WAVELENGTH OBSERVATIONS OF SUPERNOVA 2011ei: TIME-DEPENDENT CLASSIFICATION OF TYPE IIb AND Ib SUPERNOVAE AND IMPLICATIONS FOR THEIR PROGENITORS

    Energy Technology Data Exchange (ETDEWEB)

    Milisavljevic, Dan; Margutti, Raffaella; Soderberg, Alicia M.; Chomiuk, Laura; Sanders, Nathan E. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Pignata, Giuliano; Bufano, Filomena [Departamento de Ciencias Fisicas, Universidad Andres Bello, Avda. Republica 252, Santiago (Chile); Fesen, Robert A.; Parrent, Jerod T. [Department of Physics and Astronomy, Dartmouth College, 6127 Wilder Lab, Hanover, NH 03755 (United States); Parker, Stuart [Parkdale Observatory, 225 Warren Road, RDl Oxford, Canterbury 7495 (New Zealand); Mazzali, Paolo [Max-Planck-Institut fuer Astrophysik, Karl-Schwarzschild-Strasse 1, D-85748 Garching (Germany); Pian, Elena [Kavli Institute for Theoretical Physics, Kohn Hall, University of California at Santa Barbara, Santa Barbara, CA 93106-4030 (United States); Pickering, Timothy; Buckley, David A. H.; Crawford, Steven M.; Gulbis, Amanda A. S.; Hettlage, Christian [South African Astronomical Observatory, P.O. Box 9, Observatory 7935, Cape Town (South Africa); Hooper, Eric; Nordsieck, Kenneth H. [Department of Astronomy, University of Wisconsin, Madison, WI 53706 (United States); O' Donoghue, Darragh, E-mail: dmilisav@cfa.harvard.edu [Southern African Large Telescope, P.O. Box 9, Observatory 7935, Cape Town (South Africa); and others

    2013-04-10

    We present X-ray, UV/optical, and radio observations of the stripped-envelope, core-collapse supernova (SN) 2011ei, one of the least luminous SNe IIb or Ib observed to date. Our observations begin with a discovery within {approx}1 day of explosion and span several months afterward. Early optical spectra exhibit broad, Type II-like hydrogen Balmer profiles that subside rapidly and are replaced by Type Ib-like He-rich features on a timescale of one week. High-cadence monitoring of this transition suggests absorption attributable to a high-velocity ({approx}> 12, 000 km s{sup -1}) H-rich shell, which is likely present in many Type Ib events. Radio observations imply a shock velocity of v Almost-Equal-To 0.13 c and a progenitor star average mass-loss rate of M-dot {approx}1.4 Multiplication-Sign 10{sup -5} M{sub sun} yr{sup -1} (assuming wind velocity v{sub w} = 10{sup 3} km s{sup -1}). This is consistent with independent constraints from deep X-ray observations with Swift-XRT and Chandra. Overall, the multi-wavelength properties of SN 2011ei are consistent with the explosion of a lower-mass (3-4 M{sub Sun }), compact (R{sub *} {approx}< 1 Multiplication-Sign 10{sup 11} cm), He-core star. The star retained a thin hydrogen envelope at the time of explosion, and was embedded in an inhomogeneous circumstellar wind suggestive of modest episodic mass loss. We conclude that SN 2011ei's rapid spectral metamorphosis is indicative of time-dependent classifications that bias estimates of the relative explosion rates for Type IIb and Ib objects, and that important information about a progenitor star's evolutionary state and mass loss immediately prior to SN explosion can be inferred from timely multi-wavelength observations.

  8. Universal properties of type IIB and F-theory flux compactifications at large complex structure

    International Nuclear Information System (INIS)

    Marsh, M.C. David; Sousa, Kepa

    2016-01-01

    We consider flux compactifications of type IIB string theory and F-theory in which the respective superpotentials at large complex structure are dominated by cubic or quartic terms in the complex structure moduli. In this limit, the low-energy effective theory exhibits universal properties that are insensitive to the details of the compactification manifold or the flux configuration. Focussing on the complex structure and axio-dilaton sector, we show that there are no vacua in this region and the spectrum of the Hessian matrix is highly peaked and consists only of three distinct eigenvalues (0, 2m 3/2 2 and 8m 3/2 2 ), independently of the number of moduli. We briefly comment on how the inclusion of Kähler moduli affect these findings. Our results generalise those of Brodie & Marsh http://dx.doi.org/10.1007/JHEP01(2016)037, in which these universal properties were found in a subspace of the large complex structure limit of type IIB compactifications.

  9. Generalized IIB supergravity from exceptional field theory

    Energy Technology Data Exchange (ETDEWEB)

    Baguet, Arnaud; Magro, Marc; Samtleben, Henning [Laboratoire de Physique, Université Claude Bernard Lyon 1, Ens de Lyon, CNRS,F-69342 Lyon (France)

    2017-03-20

    The background underlying the η-deformed AdS{sub 5}×S{sup 5} sigma-model is known to satisfy a generalization of the IIB supergravity equations. Their solutions are related by T-duality to solutions of type IIA supergravity with non-isometric linear dilaton. We show how the generalized IIB supergravity equations can be naturally obtained from exceptional field theory. Within this manifestly duality covariant formulation of maximal supergravity, the generalized IIB supergravity equations emerge upon imposing on the fields a simple Scherk-Schwarz ansatz which respects the section constraint.

  10. Moduli stabilization in type IIB orientifolds

    International Nuclear Information System (INIS)

    Schulgin, W.

    2007-01-01

    This thesis deals with the stabilization of the moduli fields in the compactifications of the type IIB string theory on orientifolds. A concrete procedure for the construction of solutions, in which all moduli fields are fixed, yields the KKLT scenario. We study, on which models the scenario can be applied, if approximations of the original KKLT work are abandoned. We find that in a series of models, namely such without complex-structure moduli the construction of the consistent solutions in the framework of the KKLT scenario is not possible. The nonperturbative effects, like D3 instantons and gaugino condensates are a further component of the KKLT scenario. They lead to the stabilization of the Kaehler moduli. We present criteria for the generation of the superpotential due to the D3 instantons at a Calaby-Yau manifold in presence of fluxes. Furthermore we show that although the presence of the nonperturbative superpotential in the equations of motions is correlated with the switching on of all ISD and IASD fluxes, the deciding criterium for the generation of the nonperturbative superpotential depends only on the fluxes of the type (2,1). Thereafter we discuss two models, in which we stabilize all moduli fields. Thereby it deals with Calabi-Yau orientifolds which have been obtained by a blow-up procedure from the Z 6-II and Z 2 x Z 4 orientifolds

  11. Experimental data report for transient flow calibration facility tests IIB101, IIB102 and IIB201

    International Nuclear Information System (INIS)

    Wambach, J.L.

    1980-01-01

    Thermal-hydraulic response data are presented for the transient performance tests of a pitot tube rake (IIB201) and a modular drag disc-turbine transducer (DTT) rake (IIB101, IIB102). The tests were conducted in a system which provided full scale simulation of the pressure vessel and broken loop hot leg piping of the Loss of Fluid Test Facility (LOFT). A load cell system was used to provide a reference mass flow rate measurement

  12. Nonperturbative type IIB model building in the F-theory framework

    Energy Technology Data Exchange (ETDEWEB)

    Jurke, Benjamin Helmut Friedrich

    2011-02-28

    This dissertation is concerned with the topic of non-perturbative string theory, which is generally considered to be the most promising approach to a consistent description of quantum gravity. The five known 10-dimensional perturbative string theories are all interconnected by numerous dualities, such that an underlying non-perturbative 11-dimensional theory, called M-theory, is postulated. Due to several technical obstacles, little is known about the fundamental objects in this theory. There exists an alternative non-perturbative description to type IIB string theory, namely F-theory. Here the SL(2;Z) self-duality of IIB theory is geometrized in the form of an elliptic fibration over the space-time. Moreover, higher-dimensional objects like 7-branes are included via singularities into the geometric picture. This formally elegant description, however, requires significant technical effort for the construction of suitable compactification geometries, as many different aspects necessarily have to be dealt with at the same time. On the other hand, the generation of essential GUT building blocks like certain Yukawa couplings or spinor representations is easier compared to perturbative string theory. The goal of this study is therefore to formulate a unified theory within the framework of F-theory, that satisfies basic phenomenological constraints. Within this thesis, at first E3-brane instantons in type IIB string theory - 4-dimensional objects that are entirely wrapped around the invisible dimensions of space-time - are matched with M5-branes in F-theory. Such objects are of great importance in the generation of critical Yukawa couplings or the stabilization of the free parameters of a theory. Certain properties of M5-branes then allow to derive a new criterion for E3-branes to contribute to the superpotential. In the aftermath of this analysis, several compactification geometries are constructed and checked for basic properties that are relevant for semi

  13. Nonperturbative type IIB model building in the F-theory framework

    International Nuclear Information System (INIS)

    Jurke, Benjamin Helmut Friedrich

    2011-01-01

    This dissertation is concerned with the topic of non-perturbative string theory, which is generally considered to be the most promising approach to a consistent description of quantum gravity. The five known 10-dimensional perturbative string theories are all interconnected by numerous dualities, such that an underlying non-perturbative 11-dimensional theory, called M-theory, is postulated. Due to several technical obstacles, little is known about the fundamental objects in this theory. There exists an alternative non-perturbative description to type IIB string theory, namely F-theory. Here the SL(2;Z) self-duality of IIB theory is geometrized in the form of an elliptic fibration over the space-time. Moreover, higher-dimensional objects like 7-branes are included via singularities into the geometric picture. This formally elegant description, however, requires significant technical effort for the construction of suitable compactification geometries, as many different aspects necessarily have to be dealt with at the same time. On the other hand, the generation of essential GUT building blocks like certain Yukawa couplings or spinor representations is easier compared to perturbative string theory. The goal of this study is therefore to formulate a unified theory within the framework of F-theory, that satisfies basic phenomenological constraints. Within this thesis, at first E3-brane instantons in type IIB string theory - 4-dimensional objects that are entirely wrapped around the invisible dimensions of space-time - are matched with M5-branes in F-theory. Such objects are of great importance in the generation of critical Yukawa couplings or the stabilization of the free parameters of a theory. Certain properties of M5-branes then allow to derive a new criterion for E3-branes to contribute to the superpotential. In the aftermath of this analysis, several compactification geometries are constructed and checked for basic properties that are relevant for semi

  14. Type IIB orientifolds, D-brane instantons and the large volume scenario

    Energy Technology Data Exchange (ETDEWEB)

    Plauschinn, Erik

    2009-07-28

    This thesis is concerned with a branch of research in String Theory called String Phenomenology which aims for a better understanding of the connection between String Theory and Particle Physics. In particular, in this work we cover three topics which are important in order to establish this connection. The first topic is about String Theory model building in the context of so-called type IIB orientifolds with orientifold three- and seven-planes. After giving a brief overview, we work out in detail an important consistency condition for String Theory constructions, the so-called tadpole cancellation condition, and we verify explicitly that chiral anomalies are cancelled via the generalised Green-Schwarz mechanism. The second topic is concerned with so-called D-brane instantons which are nonperturbative effects in type II String Theory constructions. We recall the instanton calculus for such configurations, we derive the so-called A eck-Dine-Seiberg superpotential in String Theory and we develop an important constraint, a chiral zero-mode constraint, for instanton contributions in the presence of a realistic Particle Physics sector. The third topic is about moduli stabilisation in type IIB string compactifications. More concretely, we review the so-called KKLT as well as Large Volume Scenario, and we construct and study a model for the latter scenario where the constraint mentioned above has been taken into account explicitly. Although the three topics studied in this thesis are slightly different in nature, there is nevertheless a complex interplay between them with many interrelations. In order to uncover these connections, a detailed study of each individual subject has been performed which has led to new results such as the chiral zero-mode constraint. (orig.)

  15. Type IIB orientifolds, D-brane instantons and the large volume scenario

    International Nuclear Information System (INIS)

    Plauschinn, Erik

    2009-01-01

    This thesis is concerned with a branch of research in String Theory called String Phenomenology which aims for a better understanding of the connection between String Theory and Particle Physics. In particular, in this work we cover three topics which are important in order to establish this connection. The first topic is about String Theory model building in the context of so-called type IIB orientifolds with orientifold three- and seven-planes. After giving a brief overview, we work out in detail an important consistency condition for String Theory constructions, the so-called tadpole cancellation condition, and we verify explicitly that chiral anomalies are cancelled via the generalised Green-Schwarz mechanism. The second topic is concerned with so-called D-brane instantons which are nonperturbative effects in type II String Theory constructions. We recall the instanton calculus for such configurations, we derive the so-called A eck-Dine-Seiberg superpotential in String Theory and we develop an important constraint, a chiral zero-mode constraint, for instanton contributions in the presence of a realistic Particle Physics sector. The third topic is about moduli stabilisation in type IIB string compactifications. More concretely, we review the so-called KKLT as well as Large Volume Scenario, and we construct and study a model for the latter scenario where the constraint mentioned above has been taken into account explicitly. Although the three topics studied in this thesis are slightly different in nature, there is nevertheless a complex interplay between them with many interrelations. In order to uncover these connections, a detailed study of each individual subject has been performed which has led to new results such as the chiral zero-mode constraint. (orig.)

  16. On Type IIB moduli stabilization and N=4,8 supergravities

    Energy Technology Data Exchange (ETDEWEB)

    Aldazabal, Gerardo [Centro Atomico Bariloche, Instituto Balseiro (CNEA-UNC) and CONICET, 8400 S.C. de Bariloche (Argentina); Marques, Diego [Institut de Physique Theorique, CEA/ Saclay, 91191 Gif-sur-Yvette Cedex (France); Nunez, Carmen, E-mail: carmen@iafe.uba.a [Instituto de Astronomia y Fisica del Espacio (CONICET-UBA) and Departamento de Fisica, FCEN, Universidad de Buenos Aires, C.C. 67 - Suc. 28, 1428 Buenos Aires (Argentina); Rosabal, Jose A. [Centro Atomico Bariloche, Instituto Balseiro (CNEA-UNC) and CONICET, 8400 S.C. de Bariloche (Argentina)

    2011-08-01

    We analyze D=4 compactifications of Type IIB theory with generic, geometric and non-geometric, dual fluxes turned on. In particular, we study N=1 toroidal orbifold compactifications that admit an embedding of the untwisted sector into gauged N=4,8 supergravities. Truncations, spontaneous breaking of supersymmetry and the inclusion of sources are discussed. The algebraic identities satisfied by the supergravity gaugings are used to implement the full set of consistency constraints on the background fluxes. This allows to perform a generic study of N=1 vacua and identify large regions of the parameter space that do not admit complete moduli stabilization. Illustrative examples of AdS and Minkowski vacua are presented.

  17. String necklaces and primordial black holes from type IIB strings

    International Nuclear Information System (INIS)

    Lake, Matthew; Thomas, Steve; Ward, John

    2009-01-01

    We consider a model of static cosmic string loops in type IIB string theory, where the strings wrap cycles within the internal space. The strings are not topologically stabilised, however the presence of a lifting potential traps the windings giving rise to kinky cycloops. We find that PBH formation occurs at early times in a small window, whilst at late times we observe the formation of dark matter relics in the scaling regime. This is in stark contrast to previous predictions based on field theoretic models. We also consider the PBH contribution to the mass density of the universe, and use the experimental data to impose bounds on the string theory parameters.

  18. AdS3 xw (S3 x S3 x S1) solutions of type IIB string theory

    International Nuclear Information System (INIS)

    Donos, Aristomenis; Gauntlett, Jerome P.; Imperial College, London; Sparks, James

    2008-10-01

    We analyse a recently constructed class of local solutions of type IIB supergravity that consist of a warped product of AdS 3 with a sevendimensional internal space. In one duality frame the only other nonvanishing fields are the NS three-form and the dilaton. We analyse in detail how these local solutions can be extended to globally well-defined solutions of type IIB string theory, with the internal space having topology S 3 x S 3 x S 1 and with properly quantised three-form flux. We show that many of the dual (0,2) SCFTs are exactly marginal deformations of the (0,2) SCFTs whose holographic duals are warped products of AdS 3 with seven-dimensional manifolds of topology S 3 x S 2 x T 2 . (orig.)

  19. On a supersymmetric completion of the R4 term in IIB supergravity

    International Nuclear Information System (INIS)

    Haro, Sebastian de; Sinkovics, Annamaria; Skenderis, Kostas

    2003-01-01

    We analyze the possibility of constructing a supersymmetric invariant that contains the R 4 term among its components as a superpotential term in type IIB on-shell superspace. We consider a scalar superpotential, i.e. an arbitrary holomorphic function of a chiral scalar superfield. In general, type IIB superspace does not allow for the existence of chiral superfields, but the obstruction vanishes for a specific superfield, the dilaton superfield. This superfield contains all fields of type IIB supergravity among its components, and its existence is implied by the solution of the Bianchi identities. The construction requires the existence of an appropriate chiral measure, and we find an obstruction to the existence of such a measure. The obstruction is closely related to the obstruction for the existence of chiral superfields and is non-linear in the fields. These results imply that the type IIB superinvariant related to the R 4 term is not associated with a scalar chiral superpotential

  20. Flipped SU(5) from D-branes with type IIB fluxes

    Energy Technology Data Exchange (ETDEWEB)

    Chen Chingming [George P. and Cynthia W. Mitchell Institute for Fundamental Physics, Texas A and M University, College Station, TX 77843 (United States)]. E-mail: cchen@physics.tamu.edu; Mayes, V.E. [George P. and Cynthia W. Mitchell Institute for Fundamental Physics, Texas A and M University, College Station, TX 77843 (United States)]. E-mail: eric@physics.tamu.edu; Nanopoulos, D.V. [George P. and Cynthia W. Mitchell Institute for Fundamental Physics, Texas A and M University, College Station, TX 77843 (United States) and Astroparticle Physics Group, Houston Advanced Research Center (HARC), Mitchell Campus, Woodlands, TX 77381 (United States) and Academy of Athens, Division of Natural Sciences, 28 Panepistimiou Avenue, Athens 10679 (Greece)]. E-mail: dimitri@physics.tamu.edu

    2006-02-16

    We construct flipped SU(5) GUT models as type IIB flux vacua on Z{sub 2}xZ{sub 2} orientifolds. Turning on supergravity self-dual NSNS and RR three-form fluxes fixes the toroidal complex structure moduli and the dilaton. We give a specific example of a three-generation flipped SU(5) model with a complete Higgs sector where supersymmetry is softly broken by the supergravity fluxes in the closed string sector. All of the required Yukawa couplings are present if global U(1) factors resulting from a generalized Green-Schwarz mechanism are broken spontaneously or by world-sheet instantons. In addition, the model contains extra chiral and vector-like matter, potentially of mass O(M{sub string}) via trilinear superpotential couplings.

  1. Aspects of Moduli Stabilization in Type IIB String Theory

    Directory of Open Access Journals (Sweden)

    Shaaban Khalil

    2016-01-01

    Full Text Available We review moduli stabilization in type IIB string theory compactification with fluxes. We focus on KKLT and Large Volume Scenario (LVS. We show that the predicted soft SUSY breaking terms in KKLT model are not phenomenological viable. In LVS, the following result for scalar mass, gaugino mass, and trilinear term is obtained: m0=m1/2=-A0=m3/2, which may account for Higgs mass limit if m3/2~O(1.5 TeV. However, in this case, the relic abundance of the lightest neutralino cannot be consistent with the measured limits. We also study the cosmological consequences of moduli stabilization in both models. In particular, the associated inflation models such as racetrack inflation and Kähler inflation are analyzed. Finally, the problem of moduli destabilization and the effect of string moduli backreaction on the inflation models are discussed.

  2. Trivalent Chromium Process (TCP) as a Sealer for MIL-A-8625F Type II, IIB, and IC Anodic Coatings

    National Research Council Canada - National Science Library

    Matzdorf, Craig; Beck, Erin; Hilgeman, Amy; Prado, Ruben

    2008-01-01

    This report documents evaluations of trivalent chromium compositions (TCP) as sealers for MIL-A-8625F Type II, IIB, and IC anodic coatings conducted from March 2001 through December 2007 by Materials Engineering...

  3. Duality covariant type IIB supersymmetry and nonperturbative consequences

    CERN Document Server

    Bars, Itzhak

    1997-01-01

    Type-IIB supersymmetric theories have an SL(2,Z) invariance, known as U-duality, which controls the non-perturbative behavior of the theory. Under SL(2,Z) the supercharges are doublets, implying that the bosonic charges would be singlets or triplets. However, among the bosonic charges there are doublet strings and doublet fivebranes which are in conflict with the doublet property of the supercharges. It is shown that the conflict is resolved by structure constants that depend on moduli, such as the tau parameter, which transform under the same SL(2,Z). The resulting superalgebra encodes the non-perturbative duality properties of the theory and is valid for any value of the string coupling constant. The usefulness of the formalism is illustrated by applying it to purely algebraic computations of the tension of (p,q) strings, and the mass and entropy of extremal blackholes constructed from D-1-branes and D-5-branes. In the latter case the non-perturbative coupling dependence of the BPS mass and metric is comput...

  4. Rate type isotach compaction of consolidated sandstone

    NARCIS (Netherlands)

    Waal, J.A. de; Thienen-Visser, K. van; Pruiksma, J.P.

    2015-01-01

    Laboratory experiments on samples from a consolidated sandstone reservoir are presented that demonstrate rate type compaction behaviour similar to that observed on unconsolidated sands and soils. Such rate type behaviour can have large consequences for reservoir compaction, surface subsidence and

  5. Simultaneous bilateral Mason type IIb radial head fractures in a young female: Was an increased carrying angle the cause?

    LENUS (Irish Health Repository)

    2015-01-01

    Radial head fracture is the most common type of elbow fracture in adults. It results from a fall on an outstretched hand. However, simultaneous bilateral radial head fractures are extremely rare. We report a case of simultaneous bilateral mason type IIb radial head fractures in a young female, which was treated nonoperatively with excellent results

  6. Skeletal muscle cellularity and glycogen distribution in the hypermuscular Compact mice

    Directory of Open Access Journals (Sweden)

    T. Kocsis

    2014-07-01

    Full Text Available Normal 0 21 false false false HU X-NONE X-NONE MicrosoftInternetExplorer4 The TGF-beta member myostatin acts as a negative regulator of skeletal muscle mass. The Compact mice were selected for high protein content and hypermuscularity, and carry a naturally occurring 12-bp deletion in the propeptide region of the myostatin precursor. We aimed to investigate the cellular characteristics and the glycogen distribution of the Compact tibialis anterior (TA muscle by quantitative histochemistry and spectrophotometry. We have found that the deficiency in myostatin resulted in significantly increased weight of the investigated hindlimb muscles compared to wild type. Although the average glycogen content of the individual fibers kept unchanged, the total amount of glycogen in the Compact TA muscle increased two-fold, which can be explained by the presence of more fibers in Compact compared to wild type muscle. Moreover, the ratio of the most glycolytic IIB fibers significantly increased in the Compact TA muscle, of which glycogen content was the highest among the fast fibers. In summary, myostatin deficiency caused elevated amount of glycogen in the TA muscle but did not increase the glycogen content of the individual fibers despite the marked glycolytic shift observed in Compact mice.

  7. Precision holography for N={2}^{\\ast } on S 4 from type IIB supergravity

    Science.gov (United States)

    Bobev, Nikolay; Gautason, Friðrik Freyr; van Muiden, Jesse

    2018-04-01

    We find a new supersymmetric solution of type IIB supergravity which is holographically dual to the planar limit of the four-dimensional N={2}^{\\ast } supersymmetric Yang-Mills theory on S 4. We study a probe fundamental string in this background which is dual to a supersymmetric Wilson loop in the N={2}^{\\ast } theory. Using holography we calculate the expectation value of this line operator to leading order in the 't Hooft coupling. The result is a non-trivial function of the mass parameter of the N={2}^{\\ast } theory that precisely matches the result from supersymmetric localization.

  8. Supernova 2010as: the lowest-velocity member of a family of flat-velocity type IIb supernovae

    Energy Technology Data Exchange (ETDEWEB)

    Folatelli, Gastón; Bersten, Melina C.; Nomoto, Ken' ichi [Kavli Institute for the Physics and Mathematics of the Universe (WPI), The University of Tokyo, Kashiwa, Chiba 277-8583 (Japan); Kuncarayakti, Hanindyo; Hamuy, Mario [Departamento de Astronomía, Universidad de Chile, Casilla 36-D, Santiago (Chile); Olivares Estay, Felipe; Pignata, Giuliano [Departamento de Ciencias Fisicas, Universidad Andres Bello, Avda. Republica 252, Santiago (Chile); Anderson, Joseph P. [European Southern Observatory, Alonso de Cordova 3107, Vitacura, Santiago (Chile); Holmbo, Simon; Stritzinger, Maximilian [Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, DK-8000 Aarhus C (Denmark); Maeda, Keiichi [Department of Astronomy, Kyoto University, Kitashirakawa-Oiwake-cho, Sakyo-ku, Kyoto 606-8502 (Japan); Morrell, Nidia; Contreras, Carlos; Phillips, Mark M. [Las Campanas Observatory, Carnegie Observatories, Casilla 601, La Serena (Chile); Förster, Francisco [Center for Mathematical Modelling, Universidad de Chile, Avenida Blanco Encalada 2120 Piso 7, Santiago (Chile); Prieto, José Luis [Department of Astrophysical Sciences, Princeton University, 4 Ivy Lane, Peyton Hall, Princeton, NJ 08544 (United States); Valenti, Stefano [Las Cumbres Observatory Global Telescope Network, 6740 Cortona Drive, Suite 102, Goleta, CA 93117 (United States); Afonso, Paulo; Altenmüller, Konrad; Elliott, Jonny, E-mail: gaston.folatelli@ipmu.jp [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstraße 1, D-85740 Garching (Germany); and others

    2014-09-01

    We present extensive optical and near-infrared photometric and spectroscopic observations of the stripped-envelope supernova SN 2010as. Spectroscopic peculiarities such as initially weak helium features and low expansion velocities with a nearly flat evolution place this object in the small family of events previously identified as transitional Type Ib/c supernovae (SNe). There is ubiquitous evidence of hydrogen, albeit weak, in this family of SNe, indicating that they are in fact a peculiar kind of Type IIb SNe that we name 'flat-velocity' Type IIb. The flat-velocity evolution—which occurs at different levels between 6000 and 8000 km s{sup –1} for different SNe—suggests the presence of a dense shell in the ejecta. Despite the spectroscopic similarities, these objects show surprisingly diverse luminosities. We discuss the possible physical or geometrical unification picture for such diversity. Using archival Hubble Space Telescope images, we associate SN 2010as with a massive cluster and derive a progenitor age of ≈6 Myr, assuming a single star-formation burst, which is compatible with a Wolf-Rayet progenitor. Our hydrodynamical modeling, on the contrary, indicates that the pre-explosion mass was relatively low, ≈4 M {sub ☉}. The seeming contradiction between a young age and low pre-SN mass may be solved by a massive interacting binary progenitor.

  9. Superdualities, brane tensions and massive IIA/IIB duality

    International Nuclear Information System (INIS)

    Lavrinenko, I.V.; Lue, H.; Pope, C.N.; Stelle, K.S.

    1999-01-01

    The gauge transformations of p-form fields in supergravity theories acquire a non-commuting character when one introduces potentials both for the theory's original field strengths and for their duals. This has previously been shown in the 'doubled' formalism for maximal supergravities, where a generalised duality relation between original and dual field strengths replaces the equations of motion. In the doubled formalism, the gauge transformations generate a superalgebra, and the corresponding symmetries have accordingly been called 'superdualities'. The corresponding Noether charges form a representation of the cohomology ring on the space-time manifold. In this paper, we show that the gauge symmetry superalgebra implies certain non-trivial relations among the various p-brane tensions, which can straightforwardly be read off from the superalgebra commutation relations. This provides an elegant derivation of the brane-tension relations purely within a given theory, without the need to make use of duality relations between different theories, such as the type IIA/IIB T-duality, although the results are consistent with such dualities. We present the complete set of brane-tension relations in M-theory, in the type IIA and type IIB theories, and in all the lower-dimensional maximal supergravities. We also construct a doubled formalism for massive type IIA supergravity, and this enables us to obtain the brane-tension relations involving the D8-brane, purely within the framework of the massive IIA theory. We also obtain explicit transformations for the nine-dimensional T-duality between the massive type IIA theory and the Scherk-Schwarz reduced type IIB theory

  10. Applications of the D-instanton calculus in type IIB orientifold compactifications

    Energy Technology Data Exchange (ETDEWEB)

    Moster, Sebastian

    2010-06-22

    In this thesis string compactifications are studied in the formalism of the large-volume type IIB string theory. This class of compactifications possesses an in various regards phenomenologically interesting effective low-energy field theory. Theme of this thesis is the further development of these models motivated by recent knowledges in the D-brane instanton calculus of the string theory. After a short, general introduction in the string theory and especially in type IIB orbifolds and their consistency conditions the large-volume models are extensively presented and the hitherto knowledges on their phenomenology - like scale hierarchies, gauge couplings, supersymmetry breaking, and cosmological questions - discussed. An essential part in the construction of the large-volume models is the stabilizing of moduli fields by means of nonperturbative contribution to the superpotential in the effective low-energy field theory, which are caused by D-brane instantons or gaugino condensates. With recent knowledges in the D-brane instanton calculus it is shown that the moduli stabilization with the hitherto applied mechanism is not compatible with the existence of chiral fermions, as they occur in the standard model of elementary particle physics. A modified mechanism is proposed, in which the moduli fields are stabilized by additions of D-terms. Then by so-called ''polyinstanton corrections'' for the gauge-kinetic function a new large-volume scenario is constructed, in which the string scale without fine tuning lies not in an as in these model usual intermediate range of about 10{sup 11} GeV, but at 10{sup 16} GeV. By this this construction becomes interesting also for grand unified theories with SU(5) or SO(10) gauge groups. This is demonstrated on explicit models. Finally supersymmetry breaking is treated in large-volume scenarios. By the new mechanism for the moduli stabilization it is suggested that the supersymmetry breaking is caused by a

  11. The type IIb supernova 2013df and its cool supergiant progenitor

    Energy Technology Data Exchange (ETDEWEB)

    Van Dyk, Schuyler D. [Spitzer Science Center/Caltech, Mail Code 220-6, Pasadena, CA 91125 (United States); Zheng, WeiKang; Fox, Ori D.; Clubb, Kelsey I.; Filippenko, Alexei V.; Kelly, Patrick L. [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Cenko, S. Bradley [Astrophysics Science Division, NASA Goddard Space Flight Center, Mail Code 661, Greenbelt, MD 20771 (United States); Foley, Ryan J. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Miller, Adam A. [Jet Propulsion Laboratory, MS 169-506, Pasadena, CA 91109 (United States); Smith, Nathan [Steward Observatory, University of Arizona, Tucson, AZ 85720 (United States); Lee, William H. [Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264, Cd. Universitaria, México DF 04510 (Mexico); Ben-Ami, Sagi; Gal-Yam, Avishay, E-mail: vandyk@ipac.caltech.edu [Benoziyo Center for Astrophysics, The Weizmann Institute of Science, Rehovot 76100 (Israel)

    2014-02-01

    We have obtained early-time photometry and spectroscopy of supernova (SN) 2013df in NGC 4414. The SN is clearly of Type IIb, with notable similarities to SN 1993J. From its luminosity at secondary maximum light, it appears that less {sup 56}Ni (≲ 0.06 M {sub ☉}) was synthesized in the SN 2013df explosion than was the case for the SNe IIb 1993J, 2008ax, and 2011dh. Based on a comparison of the light curves, the SN 2013df progenitor must have been more extended in radius prior to explosion than the progenitor of SN 1993J. The total extinction for SN 2013df is estimated to be A{sub V} = 0.30 mag. The metallicity at the SN location is likely to be solar. We have conducted Hubble Space Telescope (HST) Target of Opportunity observations of the SN with the Wide Field Camera 3, and from a precise comparison of these new observations to archival HST observations of the host galaxy obtained 14 yr prior to explosion, we have identified the progenitor of SN 2013df to be a yellow supergiant, somewhat hotter than a red supergiant progenitor for a normal Type II-Plateau SN. From its observed spectral energy distribution, assuming that the light is dominated by one star, the progenitor had effective temperature T {sub eff} = 4250 ± 100 K and a bolometric luminosity L {sub bol} = 10{sup 4.94±0.06} L {sub ☉}. This leads to an effective radius R {sub eff} = 545 ± 65 R {sub ☉}. The star likely had an initial mass in the range of 13-17 M {sub ☉}; however, if it was a member of an interacting binary system, detailed modeling of the system is required to estimate this mass more accurately. The progenitor star of SN 2013df appears to have been relatively similar to the progenitor of SN 1993J.

  12. Applications of the D-instanton calculus in type IIB orientifold compactifications

    International Nuclear Information System (INIS)

    Moster, Sebastian

    2010-01-01

    In this thesis string compactifications are studied in the formalism of the large-volume type IIB string theory. This class of compactifications possesses an in various regards phenomenologically interesting effective low-energy field theory. Theme of this thesis is the further development of these models motivated by recent knowledges in the D-brane instanton calculus of the string theory. After a short, general introduction in the string theory and especially in type IIB orbifolds and their consistency conditions the large-volume models are extensively presented and the hitherto knowledges on their phenomenology - like scale hierarchies, gauge couplings, supersymmetry breaking, and cosmological questions - discussed. An essential part in the construction of the large-volume models is the stabilizing of moduli fields by means of nonperturbative contribution to the superpotential in the effective low-energy field theory, which are caused by D-brane instantons or gaugino condensates. With recent knowledges in the D-brane instanton calculus it is shown that the moduli stabilization with the hitherto applied mechanism is not compatible with the existence of chiral fermions, as they occur in the standard model of elementary particle physics. A modified mechanism is proposed, in which the moduli fields are stabilized by additions of D-terms. Then by so-called ''polyinstanton corrections'' for the gauge-kinetic function a new large-volume scenario is constructed, in which the string scale without fine tuning lies not in an as in these model usual intermediate range of about 10 11 GeV, but at 10 16 GeV. By this this construction becomes interesting also for grand unified theories with SU(5) or SO(10) gauge groups. This is demonstrated on explicit models. Finally supersymmetry breaking is treated in large-volume scenarios. By the new mechanism for the moduli stabilization it is suggested that the supersymmetry breaking is caused by a completely from the MSSM

  13. Compact type mutants in apple and sour cherries

    International Nuclear Information System (INIS)

    Zagaja, S.W.; Przybyla, A.

    1976-01-01

    Induction of mutations in deciduous fruits is considered complementary to the conventional breeding methods. Several promissing mutants, particularly in apples, were described and some of them were introduced to commercial orchards. Studies described herein are aimed at developing compact type mutants in apple cultivars, apple rootstocks and in sour cherry cultivars. Data obtained so far confirm the results of the other authors, who developed compact type mutants in apples and sweet cherries. Physiological studies have shown that the leaves of spontaneous apple mutants of compact type are more efficient in photosynthesis than the leaves of respective standards. In spite of this, using branch ringing techniques, it was found that the leaves of compacts and those of standards do not differ in their productivity. There seem to be several advantages in employing tissue culture technique in mutation breeding. That is why a project was started to work out a method of growing apple shoots from adventitious buds developed on sections of roots. (author)

  14. The type IIB string axiverse and its low-energy phenomenology

    International Nuclear Information System (INIS)

    Cicoli, Michele; Goodsell, Mark D.; Ringwald, Andreas

    2012-06-01

    We study closed string axions in type IIB orientifold compactifications. We show that for natural values of the background fluxes the moduli stabilisation mechanism of the LARGE Volume Scenario (LVS) gives rise to an axiverse characterised by the presence of a QCD axion plus many light axion-like particles whose masses are logarithmically hierarchical. We study the phenomenological features of the LVS axiverse, deriving the masses of the axions and their couplings to matter and gauge fields. We also determine when closed string axions can solve the strong CP problem, and analyse the first explicit examples of semi-realistic models with stable moduli and a QCD axion candidate which is not eaten by an anomalous Abelian gauge boson. We discuss the impact of the choice of inflationary scenario on the LVS axiverse, and summarise the astrophysical, cosmological and experimental constraints upon it. Moreover, we show how models can be constructed with additional light axion-like particles that could explain some intriguing astrophysical anomalies, and could be searched for in the next generation of axion helioscopes and light-shining-through-a-wall experiments.

  15. The type IIB string axiverse and its low-energy phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Cicoli, Michele [Abdus Salam International Centre for Theoretical Physics, Trieste (Italy); INFN, Sezione di Trieste (Italy); Goodsell, Mark D. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2012-06-15

    We study closed string axions in type IIB orientifold compactifications. We show that for natural values of the background fluxes the moduli stabilisation mechanism of the LARGE Volume Scenario (LVS) gives rise to an axiverse characterised by the presence of a QCD axion plus many light axion-like particles whose masses are logarithmically hierarchical. We study the phenomenological features of the LVS axiverse, deriving the masses of the axions and their couplings to matter and gauge fields. We also determine when closed string axions can solve the strong CP problem, and analyse the first explicit examples of semi-realistic models with stable moduli and a QCD axion candidate which is not eaten by an anomalous Abelian gauge boson. We discuss the impact of the choice of inflationary scenario on the LVS axiverse, and summarise the astrophysical, cosmological and experimental constraints upon it. Moreover, we show how models can be constructed with additional light axion-like particles that could explain some intriguing astrophysical anomalies, and could be searched for in the next generation of axion helioscopes and light-shining-through-a-wall experiments.

  16. Synthesis and characterization of p-type boron-doped IIb diamond large single crystals

    International Nuclear Information System (INIS)

    Li Shang-Sheng; Li Xiao-Lei; Su Tai-Chao; Jia Xiao-Peng; Ma Hong-An; Huang Guo-Feng; Li Yong

    2011-01-01

    High-quality p-type boron-doped IIb diamond large single crystals are successfully synthesized by the temperature gradient method in a china-type cubic anvil high-pressure apparatus at about 5.5 GPa and 1600 K. The morphologies and surface textures of the synthetic diamond crystals with different boron additive quantities are characterized by using an optical microscope and a scanning electron microscope respectively. The impurities of nitrogen and boron in diamonds are detected by micro Fourier transform infrared technique. The electrical properties including resistivities, Hall coefficients, Hall mobilities and carrier densities of the synthesized samples are measured by a four-point probe and the Hall effect method. The results show that large p-type boron-doped diamond single crystals with few nitrogen impurities have been synthesized. With the increase of quantity of additive boron, some high-index crystal faces such as {113} gradually disappear, and some stripes and triangle pits occur on the crystal surface. This work is helpful for the further research and application of boron-doped semiconductor diamond. (cross-disciplinary physics and related areas of science and technology)

  17. Compactly Supported Curvelet-Type Systems

    DEFF Research Database (Denmark)

    Rasmussen, Kenneth Niemann; Nielsen, Morten

    2012-01-01

    We study a flexible method for constructing curvelet-type frames. These curvelet-type systems have the same sparse representation properties as curvelets for appropriate classes of smooth functions, and the flexibility of the method allows us to give a constructive description of how to construct...... curvelet-type systems with a prescribed nature such as compact support in direct space. The method consists of using the machinery of almost diagonal matrices to show that a system of curvelet molecules which is sufficiently close to curvelets constitutes a frame for curvelet-type spaces. Such a system...

  18. Late-time spectral line formation in Type IIb supernovae, with application to SN 1993J, SN 2008ax, and SN 2011dh

    Science.gov (United States)

    Jerkstrand, A.; Ergon, M.; Smartt, S. J.; Fransson, C.; Sollerman, J.; Taubenberger, S.; Bersten, M.; Spyromilio, J.

    2015-01-01

    We investigate line formation processes in Type IIb supernovae (SNe) from 100 to 500 days post-explosion using spectral synthesis calculations. The modelling identifies the nuclear burning layers and physical mechanisms that produce the major emission lines, and the diagnostic potential of these. We compare the model calculations with data on the three best observed Type IIb SNe to-date - SN 1993J, SN 2008ax, and SN 2011dh. Oxygen nucleosynthesis depends sensitively on the main-sequence mass of the star and modelling of the [O I] λλ6300, 6364 lines constrains the progenitors of these three SNe to the MZAMS = 12-16 M⊙ range (ejected oxygen masses 0.3-0.9 M⊙), with SN 2011dh towards the lower end and SN 1993J towards the upper end of the range. The high ejecta masses from MZAMS ≳ 17 M⊙ progenitors give rise to brighter nebular phase emission lines than observed. Nucleosynthesis analysis thus supports a scenario of low-to-moderate mass progenitors for Type IIb SNe, and by implication an origin in binary systems. We demonstrate how oxygen and magnesium recombination lines may be combined to diagnose the magnesium mass in the SN ejecta. For SN 2011dh, a magnesium mass of 0.02-0.14 M⊙ is derived, which gives a Mg/O production ratio consistent with the solar value. Nitrogen left in the He envelope from CNO burning gives strong [N II] λλ6548, 6583 emission lines that dominate over Hα emission in our models. The hydrogen envelopes of Type IIb SNe are too small and dilute to produce any noticeable Hα emission or absorption after ~150 days, and nebular phase emission seen around 6550 Å is in many cases likely caused by [N II] λλ6548, 6583. Finally, the influence of radiative transport on the emergent line profiles is investigated. Significant line blocking in the metal core remains for several hundred days, which affects the emergent spectrum. These radiative transfer effects lead to early-time blueshifts of the emission line peaks, which gradually

  19. Duality covariant type-IIB supersymmetry and nonperturbative consequences

    International Nuclear Information System (INIS)

    Bars, I.

    1997-01-01

    Type-IIB supersymmetric theories have an SL(2,Z) invariance, known as U duality, which controls the nonperturbative behavior of the theory. Under SL(2,Z) the supercharges are doublets, implying that the bosonic charges would be singlets or triplets. However, among the bosonic charges there are doublet strings and doublet five-branes which are in conflict with the doublet property of the supercharges. It is shown that the conflict is resolved by structure constants that depend on moduli, such as the tau parameter, which transform under the same SL(2,Z). The resulting superalgebra encodes the nonperturbative duality properties of the theory and is valid for any value of the string coupling constant. The usefulness of the formalism is illustrated by applying it to purely algebraic computations of the tension of (p,q) strings, and the mass and entropy of extremal black holes constructed from D-1-branes and D-5-branes. In the latter case the nonperturbative coupling dependence of the BPS mass and renormalization is computed for the first time in this paper. It is further argued that the moduli dependence of the superalgebra provides hints for four more dimensions beyond ten, such that the superalgebra is embedded in a fundamental theory which would be covariant under SO(11,3). An outline is given for a matrix theory in 14 dimensions that would be consistent with M(atrix) theory as well as with the above observations. copyright 1997 The American Physical Society

  20. VLBI OBSERVATIONS OF THE NEARBY TYPE IIb SUPERNOVA 2011dh

    International Nuclear Information System (INIS)

    Bietenholz, M. F.; Brunthaler, A.; Soderberg, A. M.; Zauderer, B.; Krauss, M.; Chomiuk, L.; Rupen, M. P.; Bartel, N.

    2012-01-01

    We report on phase-referenced very long baseline interferometry radio observations of the Type IIb supernova 2011dh, at times t = 83 days and 179 days after the explosion and at frequencies, respectively, of 22.2 and 8.4 GHz. We detected SN 2011dh at both epochs. At the first epoch only an upper limit on SN 2011dh's angular size was obtained, but at the second epoch, we determine the angular radius of SN 2011dh's radio emission to be 0.25 ± 0.08 mas by fitting a spherical shell model directly to the visibility measurements. At a distance of 8.4 Mpc, this angular radius corresponds to a time-averaged (since t = 0) expansion velocity of the forward shock of 21, 000 ± 7000 km s –1 . Our measured values of the radius of the emission region are in excellent agreement with those derived from fitting synchrotron self-absorbed models to the radio spectral energy distribution, providing strong confirmation for the latter method of estimating the radius. We find that SN 2011dh's radius evolves in a power-law fashion, with R∝t 0.92±0.10 .

  1. Cloning of zebrafish activin type IIB receptor (ActRIIB) cDNA and mRNA expression of ActRIIB in embryos and adult tissues.

    Science.gov (United States)

    Garg, R R; Bally-Cuif, L; Lee, S E; Gong, Z; Ni, X; Hew, C L; Peng, C

    1999-07-20

    A full-length cDNA encoding for activin type IIB receptor (ActRIIB) was cloned from zebrafish embryos. It encodes a protein with 509 amino acids consisting of a signal peptide, an extracellular ligand binding domain, a single transmembrane region, and an intracellular kinase domain with predicted serine/threonine specificity. The extracellular domain shows 74-91% sequence identity to human, bovine, mouse, rat, chicken, Xenopus and goldfish activin type IIB receptors, while the transmembrane region and the kinase domain show 67-78% and 82-88% identity to these known activin IIB receptors, respectively. In adult zebrafish, ActRIIB mRNA was detected by RT-PCR in the gonads, as well as in non-reproductive tissues, including the brain, heart and muscle. In situ hybridization on ovarian sections further localized ActRIIB mRNA to cytoplasm of oocytes at different stages of development. Using whole-mount in situ hybridization, ActRIIB mRNA was found to be expressed at all stages of embryogenesis examined, including the sphere, shield, tail bud, and 6-7 somite. These results provide the first evidence that ActRIIB mRNA is widely distributed in fish embryonic and adult tissues. Cloning of zebrafish ActRIIB demonstrates that this receptor is highly conserved during vertebrate evolution and provides a basis for further studies on the role of activin in reproduction and development in lower vertebrates.

  2. String loop moduli stabilisation and cosmology in IIB flux compactifications

    International Nuclear Information System (INIS)

    Cicoli, M.

    2010-01-01

    We present a detailed review of the moduli stabilisation mechanism and possible cosmological implications of the LARGE Volume Scenario (LVS) that emerges naturally in the context of type IIB Calabi-Yau flux compactifications. After a quick overview of physics beyond the Standard Model, we present string theory as the most promising candidate for a consistent theory of quantum gravity. We then give a pedagogical introduction to type IIB compactifications on Calabi-Yau orientifolds where most of the moduli are stabilised by turning on background fluxes. However in order to fix the Kaehler moduli one needs to consider several corrections beyond the leading order approximations. After presenting a survey of all the existing solutions to this problem, we derive the topological conditions on an arbitrary Calabi-Yau to obtain the LVS since it requires no fine-tuning of the fluxes and provides a natural solution of the hierarchy problem. After performing a systematic study of the behaviour of string loop corrections for general type IIB compactifications, we show how they play a crucial role to achieve full Kaehler moduli stabilisation in the LVS. Before examining the possible cosmological implication of these scenarios, we present a broad overview of string cosmology. We then notice how, in the case of K3-fibrations, string loop corrections give rise naturally to an inflationary model which yields observable gravity waves. We finally study the finite-temperature behaviour of the LVS and discuss prospects for future work. (Abstract Copyright [2010], Wiley Periodicals, Inc.)

  3. On the non-existence of totally localised intersections of D3/D5 branes in type IIB SUGRA

    Energy Technology Data Exchange (ETDEWEB)

    Patino, Leonardo [Department of Mathematical Sciences, University of Durham, Durham, DH1 3LE (United Kingdom); Smith, Douglas [Department of Mathematical Sciences, University of Durham, Durham, DH1 3LE (United Kingdom)

    2005-04-01

    In the present paper we study the most general configuration of intersecting D3/D5 branes in type IIB supergravity satisfying Poincare invariance in the directions common to the branes and SO(3) symmetry in the totally perpendicular directions. The form of these configurations is greatly restricted by the Killing spinor equations and the equations of motion, which among other things, force the Ramond-Ramond scalar to be zero and do not permit the existence of totally localised intersections of this kind.

  4. On the non-existence of totally localised intersections of D3/D5 branes in type IIB SUGRA

    International Nuclear Information System (INIS)

    Patino, Leonardo; Smith, Douglas

    2005-01-01

    In the present paper we study the most general configuration of intersecting D3/D5 branes in type IIB supergravity satisfying Poincare invariance in the directions common to the branes and SO(3) symmetry in the totally perpendicular directions. The form of these configurations is greatly restricted by the Killing spinor equations and the equations of motion, which among other things, force the Ramond-Ramond scalar to be zero and do not permit the existence of totally localised intersections of this kind

  5. GUTs in type IIB orientifold compactifications

    International Nuclear Information System (INIS)

    Blumenhagen, Ralph; Braun, Volker; Grimm, Thomas W.; Weigand, Timo

    2009-01-01

    We systematically analyse globally consistent SU(5) GUT models on intersecting D7-branes in genuine Calabi-Yau orientifolds with O3- and O7-planes. Beyond the well-known tadpole and K-theory cancellation conditions there exist a number of additional subtle but quite restrictive constraints. For the realisation of SU(5) GUTs with gauge symmetry breaking via U(1) Y flux we present two classes of suitable Calabi-Yau manifolds defined via del Pezzo transitions of the elliptically fibred hypersurface P 1,1,1,6,9 [18] and of the Quintic P 1,1,1,1,1 [5], respectively. To define an orientifold projection we classify all involutions on del Pezzo surfaces. We work out the model building prospects of these geometries and present five globally consistent string GUT models in detail, including a 3-generation SU(5) model with no exotics whatsoever. We also realise other phenomenological features such as the 10105 H Yukawa coupling and comment on the possibility of moduli stabilisation, where we find an entire new set of so-called swiss-cheese type Calabi-Yau manifolds. It is expected that both the general constrained structure and the concrete models lift to F-theory vacua on compact Calabi-Yau fourfolds.

  6. Flow and transport at the Las Cruces trench site: Experiment IIb

    Energy Technology Data Exchange (ETDEWEB)

    Vinson, J.; Hills, R.G. [New Mexico State Univ., Las Cruces, NM (United States); Wierenga, P.J.; Young, M.H. [Arizona Univ., Tucson, AZ (United States). Dept. of Soil and Water Science

    1997-07-01

    The US Nuclear Regulatory Commission (NRC) has been directed by Congress in the Low Level Waste Policy Act of 1980 to develop regulatory guidance and assist the individual states and compacts in siting and assessing future low level radioactive waste (LLW) disposal facilities. Three water flow and solute transport experiments were performed as part of a comprehensive field trench study near Las Cruces, New Mexico to test deterministic and stochastic models of vadose zone flow and transport. This report presents partial results from the third experiment (experiment IIb). Experiments IIa and b were conducted on the North side of the trench, on a plot 1.22 m wide by 12 m long, perpendicular to the trench. The area was drip irrigated during two time periods with water containing a variety of tracers. The advance of the water front during the two irrigation episodes was measured with tensiometers and neutron probes. Solute front positions were determined from soil solution sampling through suction samplers and from disturbed sampling. The results from experiment IIb show predominantly downward water movement through the layered unsaturated soil, as evidenced from neutron probe data and gravimetric sampling. Tritium plumes were only half as deep and half as wide as the water plumes at 310 days after the beginning of experiment IIb. Chromium, applied as Cr(VI), moved a readily as, and similar to tritium, but there was a loss of mass due to reduction of Cr(VI) to Cr(III). Chloride and nitrate, initially present at high concentrations in the soil solution, were displaced by the low concentration irrigation water, resulting in chloride and nitrate concentration distributions that looked like negative images of the tritium distributions. The extensive data presented should serve well as a data base for model testing.

  7. Flow and transport at the Las Cruces trench site: Experiment IIb

    International Nuclear Information System (INIS)

    Vinson, J.; Hills, R.G.; Wierenga, P.J.; Young, M.H.

    1997-07-01

    The US Nuclear Regulatory Commission (NRC) has been directed by Congress in the Low Level Waste Policy Act of 1980 to develop regulatory guidance and assist the individual states and compacts in siting and assessing future low level radioactive waste (LLW) disposal facilities. Three water flow and solute transport experiments were performed as part of a comprehensive field trench study near Las Cruces, New Mexico to test deterministic and stochastic models of vadose zone flow and transport. This report presents partial results from the third experiment (experiment IIb). Experiments IIa and b were conducted on the North side of the trench, on a plot 1.22 m wide by 12 m long, perpendicular to the trench. The area was drip irrigated during two time periods with water containing a variety of tracers. The advance of the water front during the two irrigation episodes was measured with tensiometers and neutron probes. Solute front positions were determined from soil solution sampling through suction samplers and from disturbed sampling. The results from experiment IIb show predominantly downward water movement through the layered unsaturated soil, as evidenced from neutron probe data and gravimetric sampling. Tritium plumes were only half as deep and half as wide as the water plumes at 310 days after the beginning of experiment IIb. Chromium, applied as Cr(VI), moved a readily as, and similar to tritium, but there was a loss of mass due to reduction of Cr(VI) to Cr(III). Chloride and nitrate, initially present at high concentrations in the soil solution, were displaced by the low concentration irrigation water, resulting in chloride and nitrate concentration distributions that looked like negative images of the tritium distributions. The extensive data presented should serve well as a data base for model testing

  8. A radiation-induced compact type Granny Smith apple mutation

    International Nuclear Information System (INIS)

    Hurter, N.; Van Tonder, M.J.

    1982-01-01

    More successful compact mutant clones of Granny Smith apple are being sought, for those that have so far arisen naturally have undesirable tree and fruit charateristics. For this purpose, gamma rays from a Cobalt-60 radiation unit were used to induce mutant types artificially. One compact mutation of Granny Smith was produced via re-irradiation

  9. Treatment with soluble activin type IIB-receptor improves bone mass and strength in a mouse model of Duchenne muscular dystrophy.

    Science.gov (United States)

    Puolakkainen, Tero; Ma, Hongqian; Kainulainen, Heikki; Pasternack, Arja; Rantalainen, Timo; Ritvos, Olli; Heikinheimo, Kristiina; Hulmi, Juha J; Kiviranta, Riku

    2017-01-19

    Inhibition of activin/myostatin pathway has emerged as a novel approach to increase muscle mass and bone strength. Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that leads to progressive muscle degeneration and also high incidence of fractures. The aim of our study was to test whether inhibition of activin receptor IIB ligands with or without exercise could improve bone strength in the mdx mouse model for DMD. Thirty-two mdx mice were divided to running and non-running groups and to receive either PBS control or soluble activin type IIB-receptor (ActRIIB-Fc) once weekly for 7 weeks. Treatment of mdx mice with ActRIIB-Fc resulted in significantly increased body and muscle weights in both sedentary and exercising mice. Femoral μCT analysis showed increased bone volume and trabecular number (BV/TV +80%, Tb.N +70%, P treatment of mdx mice with the soluble ActRIIB-Fc results in a robust increase in bone mass, without any additive effect by voluntary running. Thus ActRIIB-Fc could be an attractive option in the treatment of musculoskeletal disorders.

  10. Identification of a nonsense mutation at amino acid 584-arginine of platelet glycoprotein IIb in patients with type I glanzmann thrombasthenia

    International Nuclear Information System (INIS)

    Gu Jianming; Xu Wenfeng; Wang Xiaodong; Wu Qingyu; Qi Zhengwu; Ruan Changgeng

    1993-08-01

    Using southern blot, the restriction digests of genomic DNAs in eleven patients with Glanzmann thrombasthenia from ten unrelated kindred were probed with a platelet full-length GP IIb cDNA. An abnormal 2.3 kb Taq I fragment and two 1.65 kb and 0.65 kb fragments with reduced band intensity were found in the genes of two affected siblings from a family originated in city Huang Yan of Zhejiang Province. The Taq I digest of the abnormal gene was further probed with three portions of GP IIb cDNA, revealing that the heterozygous mutation was present in the region around exons 15 ∼ 17 of the GP IIb gene. Two primers for polymerase chain reaction (PCR) were then designed, and a 394 bp PCR product was generated and sequenced, indicating that a stop codon was substituted for an Arg codon at amino acid position 584 of GP IIb, and brought about a premature termination of translation and production of a shortened protein. The Western blot analysis showed that GP IIb and GP IIIa at the platelet surface were apparently deficient, it may be ascribed to the rapid turn-over of GP IIIa uncomplexed with the truncated GP II b. The abnormal 2.3 kb Tag I fragment was used as a specific genetic marker to detect the carrier status of the patient's family. The abnormal allele was proved to be derived from the mother, the two affected siblings are double heterozygotes carrying two different GP II b-defective alleles and one clinically unaffected sister has also inherited this defective allele, while the father carries another unidentified recessive abnormal GP IIb-defective allele

  11. The spectra of type IIB flux compactifications at large complex structure

    International Nuclear Information System (INIS)

    Brodie, Callum; Marsh, M.C. David

    2016-01-01

    We compute the spectra of the Hessian matrix, H, and the matrix M that governs the critical point equation of the low-energy effective supergravity, as a function of the complex structure and axio-dilaton moduli space in type IIB flux compactifications at large complex structure. We find both spectra analytically in an h − 1,2 +3 real-dimensional subspace of the moduli space, and show that they exhibit a universal structure with highly degenerate eigenvalues, independently of the choice of flux, the details of the compactification geometry, and the number of complex structure moduli. In this subspace, the spectrum of the Hessian matrix contains no tachyons, but there are also no critical points. We show numerically that the spectra of H and M remain highly peaked over a large fraction of the sampled moduli space of explicit Calabi-Yau compactifications with 2 to 5 complex structure moduli. In these models, the scale of the supersymmetric contribution to the scalar masses is strongly linearly correlated with the value of the superpotential over almost the entire moduli space, with particularly strong correlations arising for g s <1. We contrast these results with the expectations from the much-used continuous flux approximation, and comment on the applicability of Random Matrix Theory to the statistical modelling of the string theory landscape.

  12. On R4 threshold corrections in type IIB string theory and (p,q)-string instantons

    International Nuclear Information System (INIS)

    Kiritsis, E.; Pioline, B.

    1997-01-01

    We obtain the exact non-perturbative thresholds of R 4 terms in type IIB string theory compactified to eight and seven dimensions. These thresholds are given by the perturbative tree-level and one-loop results together with the contribution of the D-instantons and of the (p,q)-string instantons. The invariance under U-duality is made manifest by rewriting the sum as a non-holomorphic-invariant modular function of the corresponding discrete U-duality group. In the eight-dimensional case, the threshold is the sum of an order-1 Eisenstein series for SL(2,Z) and an order-3/2 Eisenstein series for SL(3,Z). The seven-dimensional result is given by the order-3/2 Eisenstein series for SL(5,Z). We also conjecture formulae for the non-perturbative thresholds in lower-dimensional compactifications and discuss the relation with M-theory. (orig.)

  13. Genetic organization of ascB-dapE internalin cluster serves as a potential marker for Listeria monocytogenes sublineages IIA, IIB, and IIC.

    Science.gov (United States)

    Chen, Jianshun; Fang, Chun; Zhu, Ningyu; Lv, Yonghui; Cheng, Changyong; Bei, Yijiang; Zheng, Tianlun; Fang, Weihuan

    2012-05-01

    Listeria monocytogenes is an important foodborne pathogen that comprises four genetic lineages: I, II, III, and IV. Of these, lineage II is frequently recovered from foods and environments and responsible for the increasing incidence of human listeriosis. In this study, the phylogenetic structure of lineage II was determined through sequencing analysis of the ascB-dapE internalin cluster. Fifteen sequence types proposed by multilocus sequence typing based on nine housekeeping genes were grouped into three distinct sublineages, IIA, IIB, and IIC. Organization of the ascBdapE internalin cluster could serve as a molecular marker for these sublineages, with inlGHE, inlGC2DE, and inlC2DE for IIA, IIB, and IIC, respectively. These sublineages displayed specific genetic and phenotypic characteristics. IIA and IIC showed a higher frequency of recombination (rho/theta). However, recombination events had greater effect (r/m) on IIB, leading to its high nucleotide diversity. Moreover, IIA and IIB harbored a wider range of internalin and stress-response genes, and possessed higher nisin tolerance, whereas IIC contained the largest portion of low-virulent strains owing to premature stop codons in inlA. The results of this study indicate that IIA, IIB, and IIC might occupy different ecological niches, and IIB might have a better adaptation to a broad range of environmental niches.

  14. Dual mechanism of integrin αIIbβ3 closure in procoagulant platelets.

    Science.gov (United States)

    Mattheij, Nadine J A; Gilio, Karen; van Kruchten, Roger; Jobe, Shawn M; Wieschhaus, Adam J; Chishti, Athar H; Collins, Peter; Heemskerk, Johan W M; Cosemans, Judith M E M

    2013-05-10

    Inactivation of integrin αIIbβ3 reverses platelet aggregate formation upon coagulation. Platelets from patient (Scott) and mouse (Capn1(-/-) and Ppif(-/-)) blood reveal a dual mechanism of αIIbβ3 inactivation: by calpain-2 cleavage of integrin-associated proteins and by cyclophilin D/TMEM16F-dependent phospholipid scrambling. These data provide novel insight into the switch mechanisms from aggregating to procoagulant platelets. Aggregation of platelets via activated integrin αIIbβ3 is a prerequisite for thrombus formation. Phosphatidylserine-exposing platelets with a key role in the coagulation process disconnect from a thrombus by integrin inactivation via an unknown mechanism. Here we show that αIIbβ3 inactivation in procoagulant platelets relies on a sustained high intracellular Ca(2+), stimulating intracellular cleavage of the β3 chain, talin, and Src kinase. Inhibition of calpain activity abolished protein cleavage, but only partly suppressed αIIbβ3 inactivation. Integrin αIIbβ3 inactivation was unchanged in platelets from Capn1(-/-) mice, suggesting a role of the calpain-2 isoform. Scott syndrome platelets, lacking the transmembrane protein TMEM16F and having low phosphatidylserine exposure, displayed reduced αIIbβ3 inactivation with the remaining activity fully dependent on calpain. In platelets from Ppif(-/-) mice, lacking mitochondrial permeability transition pore (mPTP) formation, agonist-induced phosphatidylserine exposure and αIIbβ3 inactivation were reduced. Treatment of human platelets with cyclosporin A gave a similar phenotype. Together, these data point to a dual mechanism of αIIbβ3 inactivation via calpain(-2) cleavage of integrin-associated proteins and via TMEM16F-dependent phospholipid scrambling with an assistant role of mPTP formation.

  15. Cucurbitacin IIb exhibits anti-inflammatory activity through modulating multiple cellular behaviors of mouse lymphocytes.

    Directory of Open Access Journals (Sweden)

    Yao Wang

    Full Text Available Cucurbitacin IIb (CuIIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. However, its action mechanism has not been completely understood. This study aimed to explore the anti-inflammatory activity of CuIIb and its underlying mechanism in mitogen-activated lymphocytes isolated from mouse mesenteric lymph nodes. The results showed that CuIIb inhibited the proliferation of concanavalin A (Con A-activated lymphocytes in a time- and dose-dependent manner. CuIIb treatment arrested their cell cycle in S and G2/M phases probably due to the disruption of the actin cytoskeleton and the modulation of p27(Kip1 and cyclin levels. Moreover, the surface expression of activation markers CD69 and CD25 on Con A-activated CD3(+ T lymphocytes was suppressed by CuIIb treatment. Both Con A- and phorbol ester plus ionomycin-induced expression of TNF-α, IFN-γ and IL-6 proteins was attenuated upon exposure to CuIIb. Mechanistically, CuIIb treatment suppressed the phosphorylation of JNK and Erk1/2 but not p38 in Con A-activated lymphocytes. Although CuIIb unexpectedly enhanced the phosphorylation of IκB and NF-κB (p65, it blocked the nuclear translocation of NF-κB (p65. In support of this, CuIIb significantly decreased the mRNA levels of IκBα and TNF-α, two target genes of NF-κB, in Con A-activated lymphocytes. In addition, CuIIb downregulated Con A-induced STAT3 phosphorylation and increased cell apoptosis. Collectively, these results suggest that CuIIb exhibits its anti-inflammatory activity through modulating multiple cellular behaviors and signaling pathways, leading to the suppression of the adaptive immune response.

  16. Inhibition of αIIbβ3 Ligand Binding by an αIIb Peptide that Clasps the Hybrid Domain to the βI Domain of β3.

    Directory of Open Access Journals (Sweden)

    Wen Hwa Lee

    Full Text Available Agonist-stimulated platelet activation triggers conformational changes of integrin αIIbβ3, allowing fibrinogen binding and platelet aggregation. We have previously shown that an octapeptide, p1YMESRADR8, corresponding to amino acids 313-320 of the β-ribbon extending from the β-propeller domain of αIIb, acts as a potent inhibitor of platelet aggregation. Here we have performed in silico modelling analysis of the interaction of this peptide with αIIbβ3 in its bent and closed (not swing-out conformation and show that the peptide is able to act as a substitute for the β-ribbon by forming a clasp restraining the β3 hybrid and βI domains in a closed conformation. The involvement of species-specific residues of the β3 hybrid domain (E356 and K384 and the β1 domain (E297 as well as an intrapeptide bond (pE315-pR317 were confirmed as important for this interaction by mutagenesis studies of αIIbβ3 expressed in CHO cells and native or substituted peptide inhibitory studies on platelet functions. Furthermore, NMR data corroborate the above results. Our findings provide insight into the important functional role of the αIIb β-ribbon in preventing integrin αIIbβ3 head piece opening, and highlight a potential new therapeutic approach to prevent integrin ligand binding.

  17. Realizing three generations of the Standard Model fermions in the type IIB matrix model

    International Nuclear Information System (INIS)

    Aoki, Hajime; Nishimura, Jun; Tsuchiya, Asato

    2014-01-01

    We discuss how the Standard Model particles appear from the type IIB matrix model, which is considered to be a nonperturbative formulation of superstring theory. In particular, we are concerned with a constructive definition of the theory, in which we start with finite-N matrices and take the large-N limit afterwards. In that case, it was pointed out recently that realizing chiral fermions in the model is more difficult than it had been thought from formal arguments at N=∞ and that introduction of a matrix version of the warp factor is necessary. Based on this new insight, we show that two generations of the Standard Model fermions can be realized by considering a rather generic configuration of fuzzy S"2 and fuzzy S"2×S"2 in the extra dimensions. We also show that three generations can be obtained by squashing one of the S"2’s that appear in the configuration. Chiral fermions appear at the intersections of the fuzzy manifolds with nontrivial Yukawa couplings to the Higgs field, which can be calculated from the overlap of their wave functions.

  18. IIB backgrounds with five-form flux

    International Nuclear Information System (INIS)

    Gran, U.; Gutowski, J.; Papadopoulos, G.

    2008-01-01

    We investigate all N=2 supersymmetric IIB supergravity backgrounds with non-vanishing five-form flux. The Killing spinors have stability subgroups Spin(7) x R 8 , SU(4) x R 8 and G 2 . In the SU(4) x R 8 case, two different types of geometry arise depending on whether the Killing spinors are generic or pure. In both cases, the backgrounds admit a null Killing vector field which leaves invariant the SU(4) x R 8 structure, and an almost complex structure in the directions transverse to the lightcone. In the generic case, the twist of the vector field is trivial but the almost complex structure is non-integrable, while in the pure case the twist is non-trivial but the almost complex structure is integrable and associated with a relatively balanced Hermitian structure. The G 2 backgrounds admit a time-like Killing vector field and two spacelike closed one-forms, and the seven directions transverse to these admit a co-symplectic G 2 structure. The Spin(7) x R 8 backgrounds are pp-waves propagating in an eight-dimensional manifold with holonomy Spin(7). In addition we show that all the supersymmetric solutions of simple five-dimensional supergravity with a time-like Killing vector field, which include the AdS 5 black holes, lift to SU(4) x R 8 pure Killing spinor IIB backgrounds. We also show that the LLM solution is associated with a co-symplectic co-homogeneity one G 2 manifold which has principal orbit S 3 xS 3

  19. The role of myostatin and activin receptor IIB in the regulation of unloading-induced myofiber type-specific skeletal muscle atrophy.

    Science.gov (United States)

    Babcock, Lyle W; Knoblauch, Mark; Clarke, Mark S F

    2015-09-15

    Chronic unloading induces decrements in muscle size and strength. This adaptation is governed by a number of molecular factors including myostatin, a potent negative regulator of muscle mass. Myostatin must first be secreted into the circulation and then bind to the membrane-bound activin receptor IIB (actRIIB) to exert its atrophic action. Therefore, we hypothesized that myofiber type-specific atrophy observed after hindlimb suspension (HLS) would be related to myofiber type-specific expression of myostatin and/or actRIIB. Wistar rats underwent HLS for 10 days, after which the tibialis anterior was harvested for frozen cross sectioning. Simultaneous multichannel immunofluorescent staining combined with differential interference contrast imaging was employed to analyze myofiber type-specific expression of myostatin and actRIIB and myofiber type cross-sectional area (CSA) across fiber types, myonuclei, and satellite cells. Hindlimb suspension (HLS) induced significant myofiber type-specific atrophy in myosin heavy chain (MHC) IIx (P Myostatin staining associated with myonuclei was less in HLS rats compared with controls, while satellite cell staining for myostatin remained unchanged. In contrast, the total number myonuclei and satellite cells per myofiber was reduced in HLS compared with ambulatory control rats (P myostatin-induced myofiber type-selective atrophy observed during chronic unloading. Copyright © 2015 the American Physiological Society.

  20. Universality and the dynamical space-time dimensionality in the Lorentzian type IIB matrix model

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Yuta [KEK Theory Center, High Energy Accelerator Research Organization,1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Nishimura, Jun [KEK Theory Center, High Energy Accelerator Research Organization,1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Graduate University for Advanced Studies (SOKENDAI),1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Tsuchiya, Asato [Department of Physics, Shizuoka University,836 Ohya, Suruga-ku, Shizuoka 422-8529 (Japan)

    2017-03-27

    The type IIB matrix model is one of the most promising candidates for a nonperturbative formulation of superstring theory. In particular, its Lorentzian version was shown to exhibit an interesting real-time dynamics such as the spontaneous breaking of the 9-dimensional rotational symmetry to the 3-dimensional one. This result, however, was obtained after regularizing the original matrix integration by introducing “infrared” cutoffs on the quadratic moments of the Hermitian matrices. In this paper, we generalize the form of the cutoffs in such a way that it involves an arbitrary power (2p) of the matrices. By performing Monte Carlo simulation of a simplified model, we find that the results become independent of p and hence universal for p≳1.3. For p as large as 2.0, however, we find that large-N scaling behaviors do not show up, and we cannot take a sensible large-N limit. Thus we find that there is a certain range of p in which a universal large-N limit can be taken. Within this range of p, the dynamical space-time dimensionality turns out to be (3+1), while for p=2.0, where we cannot take a sensible large-N limit, we observe a (5+1)d structure.

  1. Extended no-scale structure and {alpha}'{sup 2} corrections to the type IIB action

    Energy Technology Data Exchange (ETDEWEB)

    Pedro, F.G. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Rummel, M. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Hong Kong Univ. of Science and Technology (China). Inst. for Advanced Study; Westphal, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Kavali Institute for Theoretical Physics, Santa Barbara, CA (United States)

    2013-06-15

    We analyse a new N=1 string tree level correction at O({alpha}'{sup 2}) to the Kaehler potential of the volume moduli of type IIB Calabi-Yau flux compactification found recently by T. W. Grimm, R. Savelli and M. Weissenbacher (arXiv:1303.3317 [hep-th]) and its impact on the moduli potential. We find that it imposes a strong lower bound the Calabi-Yau volume in the Large Volume Scenario of moduli stabilisation. For KKLT-like scenarios we find that consistency of the action imposes an upper bound on the flux superpotential vertical stroke W{sub 0} vertical stroke or similar 10{sup 3}. We discuss the phenomenological implication of these bounds on V in the various scenarios.

  2. Towards Matrix Models in IIB Superstrings

    OpenAIRE

    Olesen, P.

    1997-01-01

    I review the properties of a matrix action of relevance for IIB superstrings. This model generalizes the action proposed by Ishibashi, Kawai, Kitazawa, and Tsuchiya by introducing an auxillary field Y, which is the matrix version of the auxillary field g in the Schild action.

  3. A review of the microscopic modeling of the 5-dim. black hole of IIB

    Indian Academy of Sciences (India)

    We review the theory of the microscopic modeling of the 5-dim. black hole of type IIB string theory in terms of the 1-5 brane system. A detailed discussion of the low energy effective Lagrangian of the brane system is presented and the black hole micro-states are identified. These considerations are valid in the strong ...

  4. Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction.

    Science.gov (United States)

    Shanley, Daniel K; Kiely, Patrick A; Golla, Kalyan; Allen, Seamus; Martin, Kenneth; O'Riordan, Ronan T; Ball, Melanie; Aplin, John D; Singer, Bernhard B; Caplice, Noel; Moran, Niamh; Moore, Tom

    2013-01-01

    Pregnancy-specific glycoproteins (PSGs) are immunoglobulin superfamily members encoded by multigene families in rodents and primates. In human pregnancy, PSGs are secreted by the syncytiotrophoblast, a fetal tissue, and reach a concentration of up to 400 ug/ml in the maternal bloodstream at term. Human and mouse PSGs induce release of anti-inflammatory cytokines such as IL-10 and TGFβ1 from monocytes, macrophages, and other cell types, suggesting an immunoregulatory function. RGD tri-peptide motifs in the majority of human PSGs suggest that they may function like snake venom disintegrins, which bind integrins and inhibit interactions with ligands. We noted that human PSG1 has a KGD, rather than an RGD motif. The presence of a KGD in barbourin, a platelet integrin αIIbβ3 antagonist found in snake venom, suggested that PSG1 may be a selective αIIbβ3 ligand. Here we show that human PSG1 binds αIIbβ3 and inhibits the platelet - fibrinogen interaction. Unexpectedly, however, the KGD is not critical as multiple PSG1 domains independently bind and inhibit αIIbβ3 function. Human PSG9 and mouse Psg23 are also inhibitory suggesting conservation of this function across primate and rodent PSG families. Our results suggest that in species with haemochorial placentation, in which maternal blood is in direct contact with fetal trophoblast, the high expression level of PSGs reflects a requirement to antagonise abundant (3 mg/ml) fibrinogen in the maternal circulation, which may be necessary to prevent platelet aggregation and thrombosis in the prothrombotic maternal environment of pregnancy.

  5. The progenitors of the compact early-type galaxies at high redshift

    International Nuclear Information System (INIS)

    Williams, Christina C.; Giavalisco, Mauro; Lee, Bomee; Cassata, Paolo; Tundo, Elena; Conselice, Christopher J.; Wiklind, Tommy; Guo, Yicheng; Barro, Guillermo; Faber, Sandra M.; Koo, David C.; Wuyts, Stijn; Bell, Eric F.; Dekel, Avishai; Ferguson, Henry C.; Grogin, Norman; Koekemoer, Anton; Hathi, Nimish; Huang, Kuang-Han; Kocevski, Dale

    2014-01-01

    We use GOODS and CANDELS images to identify progenitors of massive (M > 10 10 M ☉ ) compact early-type galaxies (ETGs) at z ∼ 1.6. Because merging and accretion increase the size of the stellar component of galaxies, if the progenitors are among known star-forming galaxies, these must be compact themselves. We select candidate progenitors among compact Lyman-break galaxies at z ∼ 3 on the basis of their mass, star-formation rate (SFR), and central stellar density, and we find that these account for a large fraction of, and possibly all, compact ETGs at z ∼ 1.6. We find that the average far-UV spectral energy distribution (SED) of the candidates is redder than that of the non-candidates, but the optical and mid-IR SED are the same, implying that the redder UV of the candidates is inconsistent with larger dust obscuration and consistent with more evolved (aging) star formation. This is in line with other evidence suggesting that compactness is a sensitive predictor of passivity among high-redshift massive galaxies. We also find that the light distribution of both the compact ETGs and their candidate progenitors does not show any extended 'halos' surrounding the compact 'core,' both in individual images and in stacks. We argue that this is generally inconsistent with the morphology of merger remnants, even if gas rich, as predicted by N-body simulations. This suggests that the compact ETGs formed via highly dissipative, mostly gaseous accretion of units whose stellar components are very small and undetected in the Hubble Space Telescope images, with their stellar mass assembling in situ, and that they have not experienced any major merging until the epoch of observations at z ∼ 1.6.

  6. The progenitors of the compact early-type galaxies at high redshift

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Christina C.; Giavalisco, Mauro; Lee, Bomee [Department of Astronomy, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003 (United States); Cassata, Paolo [Aix Marseille Université, CNRS, LAM (Laboratoire d' Astrophysique de Marseille) UMR 7326, F-13388 Marseille (France); Tundo, Elena; Conselice, Christopher J. [The School of Physics and Astronomy, University of Nottingham, Nottingham NG7 2RD (United Kingdom); Wiklind, Tommy [Joint ALMA Observatory, ESO, Santiago (Chile); Guo, Yicheng; Barro, Guillermo; Faber, Sandra M.; Koo, David C. [UCO/Lick Observatory, Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Wuyts, Stijn [Max-Planck-Institut für Extraterrestrische Physik (MPE), Postfach 1312, D-85741 Garching (Germany); Bell, Eric F. [Department of Astronomy, University of Michigan, 500 Church Street, Ann Arbor, MI 48109 (United States); Dekel, Avishai [Racah Institute of Physics, The Hebrew University, Jerusalem 91904 (Israel); Ferguson, Henry C.; Grogin, Norman; Koekemoer, Anton [Space Telescope Science Institute, 3700 San Martin Boulevard, Baltimore, MD 21218 (United States); Hathi, Nimish [Carnegie Observatories, Pasadena, CA 91101 (United States); Huang, Kuang-Han [Department of Physics and Astronomy, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218 (United States); Kocevski, Dale, E-mail: ccwillia@astro.umass.edu [Department of Physics and Astronomy, University of Kentucky, Lexington, KY 40506 (United States); and others

    2014-01-01

    We use GOODS and CANDELS images to identify progenitors of massive (M > 10{sup 10} M {sub ☉}) compact early-type galaxies (ETGs) at z ∼ 1.6. Because merging and accretion increase the size of the stellar component of galaxies, if the progenitors are among known star-forming galaxies, these must be compact themselves. We select candidate progenitors among compact Lyman-break galaxies at z ∼ 3 on the basis of their mass, star-formation rate (SFR), and central stellar density, and we find that these account for a large fraction of, and possibly all, compact ETGs at z ∼ 1.6. We find that the average far-UV spectral energy distribution (SED) of the candidates is redder than that of the non-candidates, but the optical and mid-IR SED are the same, implying that the redder UV of the candidates is inconsistent with larger dust obscuration and consistent with more evolved (aging) star formation. This is in line with other evidence suggesting that compactness is a sensitive predictor of passivity among high-redshift massive galaxies. We also find that the light distribution of both the compact ETGs and their candidate progenitors does not show any extended 'halos' surrounding the compact 'core,' both in individual images and in stacks. We argue that this is generally inconsistent with the morphology of merger remnants, even if gas rich, as predicted by N-body simulations. This suggests that the compact ETGs formed via highly dissipative, mostly gaseous accretion of units whose stellar components are very small and undetected in the Hubble Space Telescope images, with their stellar mass assembling in situ, and that they have not experienced any major merging until the epoch of observations at z ∼ 1.6.

  7. Identification of distal regulatory regions in the human alpha IIb gene locus necessary for consistent, high-level megakaryocyte expression.

    Science.gov (United States)

    Thornton, Michael A; Zhang, Chunyan; Kowalska, Maria A; Poncz, Mortimer

    2002-11-15

    The alphaIIb/beta3-integrin receptor is present at high levels only in megakaryocytes and platelets. Its presence on platelets is critical for hemostasis. The tissue-specific nature of this receptor's expression is secondary to the restricted expression of alphaIIb, and studies of the alphaIIb proximal promoter have served as a model of a megakaryocyte-specific promoter. We have examined the alphaIIb gene locus for distal regulatory elements. Sequence comparison between the human (h) and murine (m) alphaIIb loci revealed high levels of conservation at intergenic regions both 5' and 3' to the alphaIIb gene. Additionally, deoxyribonuclease (DNase) I sensitivity mapping defined tissue-specific hypersensitive (HS) sites that coincide, in part, with these conserved regions. Transgenic mice containing various lengths of the h(alpha)IIb gene locus, which included or excluded the various conserved/HS regions, demonstrated that the proximal promoter was sufficient for tissue specificity, but that a region 2.5 to 7.1 kb upstream of the h(alpha)IIb gene was necessary for consistent expression. Another region 2.2 to 7.4 kb downstream of the gene enhanced expression 1000-fold and led to levels of h(alpha)IIb mRNA that were about 30% of the native m(alpha)IIb mRNA level. These constructs also resulted in detectable h(alpha)IIb/m(beta)3 on the platelet surface. This work not only confirms the importance of the proximal promoter of the alphaIIb gene for tissue specificity, but also characterizes the distal organization of the alphaIIb gene locus and provides an initial localization of 2 important regulatory regions needed for the expression of the alphaIIb gene at high levels during megakaryopoiesis.

  8. Is inflation from unwinding fluxes IIB?

    Energy Technology Data Exchange (ETDEWEB)

    Gautason, Fridrik Freyr [Instituut voor Theoretische Fysica, K.University Leuven,Celestijnenlaan 200D, B-3001 Leuven (Belgium); Institut de Physique Théorique, Université Paris Saclay, CEA, CNRS,Orme des Merisiers, F-91191 Gif-sur-Yvette (France); Schillo, Marjorie; Riet, Thomas Van [Instituut voor Theoretische Fysica, K.University Leuven,Celestijnenlaan 200D, B-3001 Leuven (Belgium)

    2017-03-07

    In this paper we argue that the mechanism of unwinding inflation is naturally present in warped compactifications of type IIB string theory with local throats. The unwinding of flux is caused by its annihilation against branes. The resulting inflaton potential is linear with periodic modulations. We initiate an analysis of the inflationary dynamics and cosmological observables, which are highly constrained by moduli stabilization. For the simplified model of single-Kähler Calabi-Yau spaces we find that many, though not all of the consistency constraints can be satisfied. Particularly, in this simple model geometric constraints are in tension with obtaining the observed amplitude of the scalar power spectrum. However, we do find 60 efolds of inflation with a trans-Planckian field excursion which offers the hope that slightly more complicated models can lead to a fully consistent explicit construction of large field inflation of this kind.

  9. Rendimientos del colágeno, poliornitinas (tipos: IB, IIB y IC) y colágeno mas poliornitina IB, como substratos para el cultivo de ganglios ciliares disociados de embrión de pollo

    OpenAIRE

    Bustos Ruiz, M.; Alcaín Tejada, F.J.; Padilla-Alvarez, F.

    1981-01-01

    Dissociated ciliary ganglia of 8 days embryos were cultured in heart conditioned medium, employing differents substrata types: collagen, po¬lyornithines (types: IB,IIB and IC) and collagen plus polyornithine IB. The results from neuron survival (with and without prolongations) and non neuronal cells it obtained graphically. The polyornithines mollecular weights are discussed respect inductor factors binding for conditioned medium. The type IB is better than others types (IIB y IC), but collag...

  10. Boundedness and compactness of a new product-type operator from a general space to Bloch-type spaces

    Directory of Open Access Journals (Sweden)

    Stevo Stević

    2016-09-01

    Full Text Available Abstract We characterize the boundedness and compactness of a product-type operator, which, among others, includes all the products of the single composition, multiplication, and differentiation operators, from a general space to Bloch-type spaces. We also give some upper and lower bounds for the norm of the operator.

  11. Compact simulators for WWER-440 type nuclear power plants

    International Nuclear Information System (INIS)

    Vegh, E.; Janosy, J.S.

    1991-09-01

    This paper describes a compact simulator for VVER-440 type plants. Up till now three simulators have been delivered: to Paks Nuclear Power Plant (Hungary), and to Kola and Rovno NPPs (Soviet Union). In this compact simulator the modelling complexity of the plant is almost similar to that of a full-scope one apart from the Control Room being replaced by a Control Desk and four colour graphic display units. The simulation of the plant covers the whole operating range: from cold shut-down state to nominal power level. The simulator contains up to 32 different initial conditions. Moreover, every 5 minutes the simulator produces so called 'snapshots', i.e. disc images of the Data Base. Using these snapshots the instructor can go back in time (called backtracking) in order to repeat some previously passed events

  12. A critical role for topoisomerase IIb and DNA double strand breaks in transcription.

    Science.gov (United States)

    Calderwood, Stuart K

    2016-05-26

    Recent studies have indicated a novel role for topoisomerase IIb in transcription. Transcription of heat shock genes, serum-induced immediate early genes and nuclear receptor-activated genes, each required DNA double strands generated by topoisomerase IIb. Such strand breaks seemed both necessary and sufficient for transcriptional activation. In addition, such transcription was associated with initiation of the DNA damage response pathways, including the activation of the enzymes: ataxia-telangiectasia mutated (ATM), DNA-dependent protein kinase and poly (ADP ribose) polymerase 1. DNA damage response signaling was involved both in transcription and in repair of DNA breaks generated by topoisomerase IIb.

  13. Kindlins, integrin activation and the regulation of talin recruitment to αIIbβ3.

    Directory of Open Access Journals (Sweden)

    Bryan N Kahner

    Full Text Available Talins and kindlins bind to the integrin β3 cytoplasmic tail and both are required for effective activation of integrin αIIbβ3 and resulting high-affinity ligand binding in platelets. However, binding of the talin head domain alone to β3 is sufficient to activate purified integrin αIIbβ3 in vitro. Since talin is localized to the cytoplasm of unstimulated platelets, its re-localization to the plasma membrane and to the integrin is required for activation. Here we explored the mechanism whereby kindlins function as integrin co-activators. To test whether kindlins regulate talin recruitment to plasma membranes and to αIIbβ3, full-length talin and kindlin recruitment to β3 was studied using a reconstructed CHO cell model system that recapitulates agonist-induced αIIbβ3 activation. Over-expression of kindlin-2, the endogenous kindlin isoform in CHO cells, promoted PAR1-mediated and talin-dependent ligand binding. In contrast, shRNA knockdown of kindlin-2 inhibited ligand binding. However, depletion of kindlin-2 by shRNA did not affect talin recruitment to the plasma membrane, as assessed by sub-cellular fractionation, and neither over-expression of kindlins nor depletion of kindlin-2 affected talin interaction with αIIbβ3 in living cells, as monitored by bimolecular fluorescence complementation. Furthermore, talin failed to promote kindlin-2 association with αIIbβ3 in CHO cells. In addition, purified talin and kindlin-3, the kindlin isoform expressed in platelets, failed to promote each other's binding to the β3 cytoplasmic tail in vitro. Thus, kindlins do not promote initial talin recruitment to αIIbβ3, suggesting that they co-activate integrin through a mechanism independent of recruitment.

  14. Compact type-I coil planet centrifuge for counter-current chromatography.

    Science.gov (United States)

    Yang, Yi; Gu, Dongyu; Liu, Yongqiang; Aisa, Haji Akber; Ito, Yoichiro

    2010-02-19

    A compact type-I coil planet centrifuge has been developed for performing counter-current chromatography. It has a revolution radius of 10 cm and a column holder height of 5 cm compared with 37 and 50 cm in the original prototype, respectively. The reduction in the revolution radius and column length permits application of higher revolution speed and more stable balancing of the rotor which leads us to learn more about its performance and the future potential of type-I coil planet centrifuge. The chromatographic performance of this apparatus was evaluated in terms of retention of the stationary phase (S(f)), peak resolution (R(s)), theoretical plate (N) and peak retention time (t(R)). The results of the experiment indicated that increasing the revolution speed slightly improved both the retention of the stationary phase and the peak resolution while the separation time is remarkably shortened to yield an excellent peak resolution at a revolution speed of 800 rpm. With a 12 ml capacity coiled column, DNP-DL-glu, DNP-beta-ala and DNP-l-ala were resolved at R(s) of 2.75 and 2.16 within 90 min at a flow rate of 0.4 ml/min. We believe that the compact type-I coil planet centrifuge has a high analytical potential. Published by Elsevier B.V.

  15. Geology and mineral deposits of an area in the Departments of Antioquia and Caldas (Subzone IIB), Colombia

    Science.gov (United States)

    Feininger, Tomas; Barrero L., Dario; Castro, Nestor; Hall, R.B.

    1973-01-01

    The Inventario Minero National (IMN), a four-year cooperative geologic mapping and mineral resources appraisal project, was accomplished under an agreement between the Republic of Colombia and the U. S. Agency for International Development from 1964 through 1969. Subzone IIB, consisting essentially of the east half of Zone comprises nearly 20,000 km2 principally in the Department of Antioquia but including also small parts of the Departments of Caldas and Tolima. The rocks in IIB range from Precambrian to Holocene. Precambrian feldspar-quartz gneiss occupies a mosaic of fault-bounded blocks intruded by igneous rocks between the Oto fault and the Rio Magdalena. Paleozoic rocks are extensive, and include lightly metamorphosed graptolite-bearing Ordovician shale at Cristalina, and a major suite of graphitic quartz-mica schist, feldspathic and aluminous gneiss, quartzite, marble, amphibolite, and other rocks. Syntectonic intrusive gneiss included many of the older rocks during a late Paleozoic(?) orogeny, which was accompanied by Abukuma-type metamorphosing from lowermost greenschist to upper amphibolite facies. A Jurassic diorite pluton bounded by faults cuts volcanic rocks of unknown age east of the Otu fault. Cretaceous rocks are major units. Middle Cretaceous carbonaceous shale, sandstone, graywacke, conglomerate, and volcanic rocks are locally prominent. The Antioquian batholith (quartz diorite) of Late Cretaceous age cuts the middle Cretaceous and older rocks. A belt of Tertiary nonmarine clastic sedimentary rocks crops out along the Magdalena Valley. Patches of Tertiary alluvium are locally preserved in the mountains. Quaternary alluvium, much of it auriferous, is widespread in modern stream valleys. Structurally IIB constitutes part of a vast complex synclinorium intruded concordantly by syntectonic catazonal or mesozonal felsic plutons, and by the later epizonal post-tectonic Antioquian batholith. Previously unrecognized major wrench faults are outstanding

  16. Key role of integrin α(IIb)β (3) signaling to Syk kinase in tissue factor-induced thrombin generation.

    Science.gov (United States)

    van der Meijden, Paola E J; Feijge, Marion A H; Swieringa, Frauke; Gilio, Karen; Nergiz-Unal, Reyhan; Hamulyák, Karly; Heemskerk, Johan W M

    2012-10-01

    The fibrin(ogen) receptor, integrin α(IIb)β(3), has a well-established role in platelet spreading, aggregation and clot retraction. How α(IIb)β(3) contributes to platelet-dependent coagulation is less well resolved. Here, we demonstrate that the potent suppressing effect of clinically used α(IIb)β(3) blockers on tissue factor-induced thrombin generation is linked to diminished platelet Ca(2+) responses and phosphatidylserine (PS) exposure. The same blockers suppress these responses in platelets stimulated with collagen and thrombin receptor agonists, whereas added fibrinogen potentiates these responses. In platelets spreading on fibrinogen, outside-in α(IIb)β(3) signaling similarly enhances thrombin-induced Ca(2+) rises and PS exposure. These responses are reduced in α(IIb)β(3)-deficient platelets from patients with Glanzmann's thrombasthenia. Furthermore, the contribution of α(IIb)β(3) to tissue factor-induced platelet Ca(2+) rises, PS exposure and thrombin generation in plasma are fully dependent on Syk kinase activity. Tyrosine phosphorylation analysis confirms a key role of Syk activation, which is largely but not exclusively dependent on α(IIb)β(3) activation. It is concluded that the majority of tissue factor-induced procoagulant activity of platelets relies on Syk activation and ensuing Ca(2+) signal generation, and furthermore that a considerable part of Syk activation relies on α(IIb)β(3) signaling. These results hence point to a novel role of Syk in integrin-dependent thrombin generation.

  17. Effects of 1alpha-hydroxycholecalciferol on growth performance, parameters of tibia and plasma, meat quality, and type IIb sodium phosphate cotransporter gene expression of one- to twenty-one-day-old broilers.

    Science.gov (United States)

    Han, J C; Yang, X D; Zhang, T; Li, H; Li, W L; Zhang, Z Y; Yao, J H

    2009-02-01

    This experiment was conducted to investigate the effects of 1alpha-hydroxycholecalciferol (1alpha-OH D3) on the growth performance, tibia and plasma parameters, nutrient utilization, meat quality of the breast and thigh, and type IIb sodium phosphate cotranspoter gene expression of broilers. A total of 96 males of 1-d-old Arbor Acres broilers were randomly assigned to 8 cages of 12 birds each. Two dietary treatments were applied to 4 cages each. Diet 1 was prepared as the basal diet (nonphytate phosphorus, 0.21%), whereas diet 2 was the basal diet supplemented with 5 microg/kg of 1alpha-OH D3. Results showed that supplementation of the basal diet with 1alpha-OH D3 increased growth performance, tibia ash and strength, plasma inorganic phosphate concentration, utilization of total phosphorus and nonphytate phosphorus, lightness and yellowness of the breast and thigh meat, and intestinal type IIb sodium phosphate cotranspoter mRNA expression, whereas it decreased the shear force and water-holding capacity of the thigh meat. These data suggest that the addition of 1alpha-OH D3 might improve growth performance, tibia development, and meat quality in 1- to 21-d-old broilers by increasing the absorption and retention of phosphorus.

  18. Goat activin receptor type IIB knockdown by muscle specific promoter driven artificial microRNAs.

    Science.gov (United States)

    Patel, Amrutlal K; Shah, Ravi K; Patel, Utsav A; Tripathi, Ajai K; Joshi, Chaitanya G

    2014-10-10

    Activin receptor type IIB (ACVR2B) is a transmembrane receptor which mediates signaling of TGF beta superfamily ligands known to function in regulation of muscle mass, embryonic development and reproduction. ACVR2B antagonism has shown to enhance the muscle growth in several disease and transgenic models. Here, we show ACVR2B knockdown by RNA interference using muscle creatine kinase (MCK) promoter driven artificial microRNAs (amiRNAs). Among the various promoter elements tested, the ∼1.26 kb MCK promoter region showed maximum transcriptional activity in goat myoblasts cells. We observed up to 20% silencing in non-myogenic 293T cells and up to 32% silencing in myogenic goat myoblasts by MCK directed amiRNAs by transient transfection. Goat myoblasts stably integrated with MCK directed amiRNAs showed merely 8% silencing in proliferating myoblasts which was increased to 34% upon induction of differentiation at transcript level whereas up to 57% silencing at protein level. Knockdown of ACVR2B by 5'-UTR derived amiRNAs resulted in decreased SMAD2/3 signaling, increased expression of myogenic regulatory factors (MRFs) and enhanced proliferation and differentiation of myoblasts. Unexpectedly, knockdown of ACVR2B by 3'-UTR derived amiRNAs resulted in increased SMAD2/3 signaling, reduced expression of MRFs and suppression of myogenesis. Our study offers muscle specific knockdown of ACVR2B as a potential strategy to enhance muscle mass in the farm animal species. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Duality symmetries and the Type II string effective action

    International Nuclear Information System (INIS)

    Bergshoeff, E.

    1996-01-01

    We discuss the duality symmetries of Type II string effective actions in nine, ten and eleven dimensions. As a by-product we give a covariant action underlying the ten-dimensional Type IIB supergravity theory. We apply duality symmetries to construct dyonic Type II string solutions in six dimensions and their reformulation as solutions of the ten-dimensional Type IIB theory in ten dimensions. (orig.)

  20. Cervical level IIb metastases in squamous cell carcinoma of the oral cavity: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Kou Y

    2017-09-01

    Full Text Available Yurong Kou,1,* Tengfei Zhao,2,* Shaohui Huang,2 Jie Liu,3 Weiyi Duan,2 Yunjing Wang,2 Zechen Wang,2 Delong Li,2 Chunliu Ning,2 Changfu Sun2 1Department of Oral Biology, School of Stomatology, China Medical University, Shenyang, Liaoning, People’s Republic of China; 2Department of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University, Shenyang, Liaoning, People’s Republic of China; 3Centre of Science Experiment, China Medical University, Shenyang, Liaoning, People’s Republic of China *These authors contributed equally to this work Purpose: The aim of this study was to clarify whether level IIb dissection should be performed or avoided in the treatment of oral squamous cell carcinoma by meta-analysis.Materials and methods: Articles that were published before June 2017 were searched electronically in four databases (Web of Science, PubMed, Ovid and China National Knowledge Infrastructure without any date or language restrictions by two independent reviewers. Abstracts and full-text papers which investigated the cervical metastases to level IIb from primary head and neck cancers and were deemed potentially relevant were screened. Data were analyzed using RevMan 5.3.Results: Four hundred and fifty-five abstracts and 129 full-text papers were screened, and 22 studies were included in the analysis. Among the 2001 patients included, 112 patients had level IIb metastases, the pooled frequency of which was 6% (95% confidence interval [CI]: 4.0–7.0. Among the 400 patients with tongue squamous cell carcinoma from 12 studies, 37 patients had level IIb metastases, the pooled incidence of which was 7% (95% CI: 5.0–10.0. Metastases to level IIb always went together with level IIa, and only three patients were found to have isolated level IIb metastases without involving the other levels.Conclusion: Due to the low frequency of level IIb nodal metastases in oral squamous cell carcinoma patients and rare occurrence of isolated

  1. Effect of Fibers and Filler Types on Fresh and Hardened Properties of Self-Compacting Concrete

    Directory of Open Access Journals (Sweden)

    Saeed K. Rejeb* , Majid Kh . N. Ayad A. M.

    2014-04-01

    Full Text Available This paper deals with studying the fresh and hardened properties of self-compacting concrete, by using three types of filler (silica fume, clinker powder & lime stone powder, and two types of fibers (steel & glass fibers with volume fractions of (0.5% and (0.1% respectively. For each type of fillers, the fresh properties are measured by using Slump test, J- ring and V- funnel, while hardened properties include the compressive strength, splitting tensile strength and flexural strength. The results show that adding fibers to the self-compacting concrete (SCC well reduces the workability and improves the hardened properties. Also, the study concluded that better workability is obtained by using (lime stone, silica fume and clinker powder as fillers, respectively. While the higher hardened properties are gained by using silica fume were rather than those of other types of fillers 

  2. CONSOLIDATION AND COMPACTION OF POWDER MIXTURES .3. BINARY-MIXTURES OF DIFFERENT PARTICLE-SIZE FRACTIONS OF DIFFERENT TYPES OF CRYSTALLINE LACTOSE

    NARCIS (Netherlands)

    RIEPMA, KA; ZUURMAN, K; BOLHUIS, GK; DEBOER, AH; LERK, CF

    1992-01-01

    Tablets were compacted from a coarse fraction (250-315 mum), a fine fraction (32-45 mum) and from binary blends of a coarse and a fine fraction of different types of crystalline lactose. The results showed differences in consolidation and compaction between the granular lactose types, i.e.,

  3. S and U-duality constraints on IIB S-matrices

    International Nuclear Information System (INIS)

    Chalmers, Gordon

    2000-01-01

    S- and U-duality dictate that graviton scattering amplitudes in IIB superstring theory be automorphic functions on the appropriate fundamental domain which describe the inequivalent vacua of (compactified) theories. A constrained functional form of graviton scattering is proposed using Eisenstein series and their generalizations compatible with: (a) two-loop supergravity, (b) genus one superstring theory, (c) the perturbative coupling dependence of the superstring, and (d) with the unitarity structure of the massless modes. The form has a perturbative truncation in the genus expansion at a given order in the derivative expansion. Comparisons between graviton scattering S-matrices and effective actions for the first quantized superstring are made at the quantum level. Possible extended finiteness properties of maximally extended quantum supergravity theories in different dimensions is implied by the perturbative truncation of the functional form of graviton scattering in IIB superstring theory

  4. Invasive cervical carcinoma (stage IB-IIB): assessment with MR imaging

    International Nuclear Information System (INIS)

    Sironi, S.; Del Maschio, A.; Belloni, C.; Taccagni, L.

    1990-01-01

    In patients with cervical carcinoma the selection of the optimal therapy depends on the precise preoperative assessment of the extent of disease. Currently, decisions regarding the management of these patients are made on the basis of clinical (FIGO) staging that has 50% mean error rate. To investigate the value of MR imaging in staging patients with invasive cervical cancer, we performed 25 MR examinations on 23 patients with histologic diagnosis of cervical cancer. All patients were clinically considered as having stage IB or IIB disease and underwent radical hysterectomy, providing specimens for pathologic correlation. The overall accuracy of MR imaging in staging cervical carcinoma (stage IB-IIB) was 78.1%. MR imaging seems to be the most reliable preoperative modality for staging invasive cervical cancer

  5. Self-Compacting Concrete

    OpenAIRE

    Okamura, Hajime; Ouchi, Masahiro

    2003-01-01

    Self-compacting concrete was first developed in 1988 to achieve durable concrete structures. Since then, various investigations have been carried out and this type of concrete has been used in practical structures in Japan, mainly by large construction companies. Investigations for establishing a rational mix-design method and self-compactability testing methods have been carried out from the viewpoint of making self-compacting concrete a standard concrete.

  6. Contribution of inhibitory receptor glycoprotein iib / iiia in coronary angioplasty and acute coronary syndrome, about 152 patients

    International Nuclear Information System (INIS)

    Sellami, Walid

    2007-01-01

    The aim of our study was to evaluate the immediate results and long-term intake of anti-GP IIb / IIIa inhibitors for patients with acute coronary syndrome treated with coronary angioplasty. The use of anti-GP IIb / IIIa is a valid therapeutic option in patients with acute coronary syndrome with signs of severity and for patients undergoing complex angioplasty. Adverse effects of anti-GP IIb / IIIa can be seen to encourage vigilance and careful monitoring during the administration of these molecules and perfect knowledge of their pharmacological properties for appropriate use.

  7. Warped AdS{sub 6}×S{sup 2} in Type IIB supergravity II: global solutions and five-brane webs

    Energy Technology Data Exchange (ETDEWEB)

    D’Hoker, Eric; Gutperle, Michael; Uhlemann, Christoph F. [Mani L. Bhaumik Institute for Theoretical Physics,Department of Physics and Astronomy, University of California Los Angeles,475 Portola Plaza, Los Angeles, CA 90095 (United States)

    2017-05-23

    Motivated by the construction of holographic duals to five-dimensional superconformal quantum field theories, we obtain global solutions to Type IIB supergravity invariant under the superalgebra F(4) on a space-time of the form AdS{sub 6}×S{sup 2} warped over a two-dimensional Riemann surface Σ. In earlier work, the general local solutions were expressed in terms of two locally holomorphic functions A{sub ±} on Σ and global solutions were sketched when Σ is a disk. In the present paper, the physical regularity conditions on the supergravity fields required for global solutions are implemented on A{sub ±} for arbitrary Σ. Global solutions exist only when Σ has a non-empty boundary ∂Σ. The differentials ∂A{sub ±} are allowed to have poles only on ∂Σ and each pole corresponds to a semi-infinite (p,q) five-brane. The construction for the disk is carried out in detail and the conditions for the existence of global solutions are articulated for surfaces with more than one boundary and higher genus.

  8. On the effective theory of type II string compactifications on nilmanifolds and coset spaces

    International Nuclear Information System (INIS)

    Caviezel, Claudio

    2009-01-01

    In this thesis we analyzed a large number of type IIA strict SU(3)-structure compactifications with fluxes and O6/D6-sources, as well as type IIB static SU(2)-structure compactifications with fluxes and O5/O7-sources. Restricting to structures and fluxes that are constant in the basis of left-invariant one-forms, these models are tractable enough to allow for an explicit derivation of the four-dimensional low-energy effective theory. The six-dimensional compact manifolds we studied in this thesis are nilmanifolds based on nilpotent Lie-algebras, and, on the other hand, coset spaces based on semisimple and U(1)-groups, which admit a left-invariant strict SU(3)- or static SU(2)-structure. In particular, from the set of 34 distinct nilmanifolds we identified two nilmanifolds, the torus and the Iwasawa manifold, that allow for an AdS 4 , N = 1 type IIA strict SU(3)-structure solution and one nilmanifold allowing for an AdS 4 , N = 1 type IIB static SU(2)-structure solution. From the set of all the possible six-dimensional coset spaces, we identified seven coset spaces suitable for strict SU(3)-structure compactifications, four of which also allow for a static SU(2)-structure compactification. For all these models, we calculated the four-dimensional low-energy effective theory using N = 1 supergravity techniques. In order to write down the most general four-dimensional effective action, we also studied how to classify the different disconnected ''bubbles'' in moduli space. (orig.)

  9. Compactness in quasi-Banach function spaces and applications to compact embeddings of Besov-type spaces

    Czech Academy of Sciences Publication Activity Database

    Caetano, A.M.; Gogatishvili, Amiran; Opic, B.

    2016-01-01

    Roč. 146, č. 5 (2016), s. 905-927 ISSN 0308-2105 R&D Projects: GA ČR GA13-14743S Institutional support: RVO:67985840 Keywords : quasi-Banach function space * compactness * compact embedding Subject RIV: BA - General Mathematics Impact factor: 1.158, year: 2016 http:// journals .cambridge.org/action/displayAbstract?fromPage=online&aid=10379393&fileId=S0308210515000761

  10. Type IIB Ileosigmoid knotting: a case report

    African Journals Online (AJOL)

    2016-06-03

    Jun 3, 2016 ... peritonitis [4,6,7]; hence early diagnosis and operative ... clinical and radiological presentation of type II ileosigmoid volvulus ... Emergency laparotomy with possible resection and primary anastomosis in type I or resection and ...

  11. Patient satisfaction after hospital therapie of peripheral artery disease in fontaine stage IIb either with konservativ or endovascular or operativ therapy

    OpenAIRE

    Gollnick, Ingo

    2012-01-01

    Evidence-based and guideline-conforming treatment of claudication in Fontaine stage IIb due to peripheral artery disease is basically conservative. However, many patients in Fontaine stage IIb disease are treated also treated surgically, e.g. with bypass operations or endarterectomy, or with endovascular methods (angioplasty and variations thereof ). The present study compares patient satisfaction with these three therapy modalities. Methods: 666 patients with Fontaine IIb cla...

  12. Integrin α(IIb)β₃ exists in an activated state in subjects with elevated plasma homocysteine levels.

    LENUS (Irish Health Repository)

    McGarrigle, Sarah A

    2011-01-01

    Elevated levels of plasma homocysteine (Hcy) are an independent risk factor for cardiovascular disease and thrombosis. The molecular basis for this phenomenon is not known but may relate to modification of cell surface thiols. The platelet specific integrin α(IIb)β₃ is a cysteine-rich cell adhesion molecule that plays a critical role in platelet aggregation and adhesion in haemostasis and thrombosis. In this study, we looked for evidence of a homocysteine-induced modification of α(IIb)β₃ using a fluorescently labeled PAC-1 antibody that recognizes the activated conformation of the integrin on the platelet surface. We show that exogenous Hcy (10-100 µM) and homocysteine thiolactone (HcyTL) (10-100 µM) increased PAC-1 binding to platelets in a concentration dependent manner in vitro. In parallel, we show subjects with clinical hyperhomocysteinemia exhibit a greater degree of activation of α(IIb)β₃ compared to age-matched controls. These findings demonstrate that circulating Hcy can modulate the activation state of the platelet integrin α(IIb)β₃, a key player in platelet aggregation and thrombosis.

  13. Type IIB supergravity solution for the T-dual of the η-deformed AdS_5×S"5 superstring

    International Nuclear Information System (INIS)

    Hoare, B.; Tseytlin, A.A.

    2015-01-01

    We find an exact type IIB supergravity solution that represents a one-parameter deformation of the T-dual of the AdS_5×S"5 background (with T-duality applied in all 6 abelian bosonic isometric directions). The non-trivial fields are the metric, dilaton and RR 5-form only. The latter has remarkably simple “undeformed” form when written in terms of a “deformation-rotated” vielbein basis. An unusual feature of this solution is that the dilaton contains a linear dependence on the isometric coordinates of the metric precluding a straightforward reversal of T-duality. If we still formally dualize back, we find exactly the metric, B-field and product of dilaton with RR field strengths as recently extracted from the η-deformed AdS_5×S"5 superstring action in http://arxiv.org/abs/1507.04239. We also discuss similar solutions for deformed AdS_n×S"n backgrounds with n=2,3. In the η→i limit we demonstrate that all these backgrounds can be interpreted as special limits of gauged WZW models and are also related to (a limit of) the Pohlmeyer-reduced models of the AdS_n×S"n superstrings.

  14. IIB solutions with N>28 Killing spinors are maximally supersymmetric

    International Nuclear Information System (INIS)

    Gran, U.; Gutowski, J.; Papadopoulos, G.; Roest, D.

    2007-01-01

    We show that all IIB supergravity backgrounds which admit more than 28 Killing spinors are maximally supersymmetric. In particular, we find that for all N>28 backgrounds the supercovariant curvature vanishes, and that the quotients of maximally supersymmetric backgrounds either preserve all 32 or N<29 supersymmetries

  15. Compaction properties of isomalt

    NARCIS (Netherlands)

    Bolhuis, Gerad K.; Engelhart, Jeffrey J. P.; Eissens, Anko C.

    Although other polyols have been described extensively as filler-binders in direct compaction of tablets, the polyol isomalt is rather unknown as pharmaceutical excipient, in spite of its description in all the main pharmacopoeias. In this paper the compaction properties of different types of

  16. Hydroxyurea with Radiation Therapy of the Carcinoma of the Cervix IIA, IIB

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jin Hee; Youn, Seon Min; Kim, Ok Bae [Keimyung University College of Medicine, Taegu (Korea, Republic of)

    1995-12-15

    Purpose : To evaluate the efficacy of hydroxyurea with radiation in carcinoma of the cervix, huge exophytic or endophytic stage IIa and Iib. Materials and Methods : Sixty four patients with carcinoma of the cervix stage IIA(29 patients) with exophytic({>=}3cm in diameter) or huge endophytic mass and IIB(35 patients) treated with radiation and hydroxyurea at the Department of Radiation Oncology, Dongsan Hospital, Keimyung University, School of Medicine from Aug, 1989 to May, 1991. The maximum and mean follow up durations were 68 and 57 months respectively. The radiation therapy consisted of external irradiation to the whole pelvis(3600-5400cGy) shield (4X10 cm), and combined with intracavitary irradiation (3000-3500cGy to point A). Hydroxyurea was to be taken in a single oral dose of 1.0gm/day during radiation therapy. Results : The control rate was 89.1%. The actuarial overall five year survival rate was 78.8% for stage IIA and 72.8% for stage IIB. The overall recurrence rate was 25%(16/64). Twenty-three percent of the patients developed or greater thrombocytopenia. Grade 3 or greater GI, GU complication and anemia were not noted. There was no treatment related death noted. Conclusion : We considered that hydroxyurea and radiation therapy may improve survival rate in huge exophytic and endophytic stage IIa cervical carcinoma with acceptible morbidity.

  17. Hydroxyurea with Radiation Therapy of the Carcinoma of the Cervix IIA, IIB

    International Nuclear Information System (INIS)

    Kim, Jin Hee; Youn, Seon Min; Kim, Ok Bae

    1995-01-01

    Purpose : To evaluate the efficacy of hydroxyurea with radiation in carcinoma of the cervix, huge exophytic or endophytic stage IIa and Iib. Materials and Methods : Sixty four patients with carcinoma of the cervix stage IIA(29 patients) with exophytic(≥3cm in diameter) or huge endophytic mass and IIB(35 patients) treated with radiation and hydroxyurea at the Department of Radiation Oncology, Dongsan Hospital, Keimyung University, School of Medicine from Aug, 1989 to May, 1991. The maximum and mean follow up durations were 68 and 57 months respectively. The radiation therapy consisted of external irradiation to the whole pelvis(3600-5400cGy) shield (4X10 cm), and combined with intracavitary irradiation (3000-3500cGy to point A). Hydroxyurea was to be taken in a single oral dose of 1.0gm/day during radiation therapy. Results : The control rate was 89.1%. The actuarial overall five year survival rate was 78.8% for stage IIA and 72.8% for stage IIB. The overall recurrence rate was 25%(16/64). Twenty-three percent of the patients developed or greater thrombocytopenia. Grade 3 or greater GI, GU complication and anemia were not noted. There was no treatment related death noted. Conclusion : We considered that hydroxyurea and radiation therapy may improve survival rate in huge exophytic and endophytic stage IIa cervical carcinoma with acceptible morbidity

  18. Type IIB thyroplasty for phonic tics in a pediatric patient with autism spectrum disorder: a case report.

    Science.gov (United States)

    Ahmed, Mostafa M; Heckman, W Wesley; Dailey, Seth H

    2013-03-01

    Autism spectrum disorders (ASDs) are commonly associated with Tourette syndrome (TS). TS is classically associated with tic production. A tic is defined as sudden, brief, involuntary production of movement (motor tics) or sound (phonic tics). Case report. We present a case report of a 14-year-old boy with ASD and vocal tics. Vocal tic frequency was nearly 2000 per day and 90 dB in volume. He presented to our laryngology clinic after multiple failed attempts of pharmacologic management of vocal fold botulinum toxin injection. After evaluation in our clinic, we recommended a lateralization (type IIB) thyroplasty. An autologous cartilage graft from the superior thyroid ala was used and held in place with a bioresorbable mesh. Using 4-0 prolene sutures, the mesh was secured in place. The operation was well tolerated with minimal signs of aspiration, and he was discharged to his home within 48 hours. Six months postoperatively, there was 90% reduction in tic frequency and 50% reduction in intensity. Additionally, he has shown improved ability to converse with his peers, participate in school activities, and even has improved nutritional status. Alteration of laryngeal geometry could serve as an effective site of intervention for intractable phonic tics. Reduction of phonic tic frequency and intensity may also stimulate language development in patients ASD. We also demonstrate additional use of bioresorbable plates in pediatric laryngeal framework surgery. Additional neurophysiologic studies are needed to explore the mechanism by which midline lateralization thyroplasty influences phonic tic generation. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  19. The effects of age on treatment and outcomes in women with stages IB1-IIB cervical cancer.

    Science.gov (United States)

    Roque, Dario R; Cronin, Beth; Robison, Katina; Lopes, Vrishali; Rizack, Tina; Dizon, Don S

    2013-10-01

    Age may affect the treatment choice and subsequent outcome in elderly patients with cervical cancer. Given the potential for cure with either surgery or chemoradiation in early stage disease, we aimed to determine whether a patient's age influenced treatment received and the ensuing outcome. We identified 303 patients with stages IB1-IIB cervical carcinoma treated at our institution between 2000 and 2010, who were divided into two groups based on age at time of diagnosis: stage at presentation, and grade. Women ≥ 65 years of age were less likely to receive primary surgical management (p=0.03). Age did not influence disease-specific or all-cause mortality. However, women over 65 years who underwent primary surgery were at significantly increased risk of all-cause mortality compared to younger women (HR 6.53, 95% CI: 2.57-16.6). Age appears to influence treatment received by patients with stages IB1-IIB cervical cancer. Although there was no difference in cancer-specific mortality stratified by type of treatment received, surgery was associated with a 6.5-fold increased risk of all-cause mortality among women 65 years or over. © 2013.

  20. Di-J/ψ Studies, Level 3 Tracking and the D0 Run IIb Upgrade

    International Nuclear Information System (INIS)

    Vint, Philip John

    2009-01-01

    The D0 detector underwent an upgrade to its silicon vertex detector and triggering systems during the transition from Run IIa to Run IIb to maximize its ability to fully exploit Run II at the Fermilab Tevatron. This thesis describes improvements made to the tracking and vertexing algorithms used by the high level trigger in both Run IIa and Run IIb, as well as a search for resonant di-J/ψ states using both Run IIa and Run IIb data. Improvements made to the tracking and vertexing algorithms during Run IIa included the optimization of the existing tracking software to reduce overall processing time and the certification and testing of a new software release. Upgrades made to the high level trigger for Run IIb included the development of a new tracking algorithm and the inclusion of the new Layer 0 silicon detector into the existing software. The integration of Layer 0 into the high level trigger has led to an improvement in the overall impact parameter resolution for tracks of ∼50%. The development of a new parameterization method for finding the error associated to the impact parameter of tracks returned by the high level tracking algorithm, in association with the inclusion of Layer 0, has led to improvements in vertex resolution of ∼4.5 (micro)m. A previous search in the di-J/ψ channel revealed a unpredicted resonance at ∼13.7 GeV/c 2 . A confirmation analysis is presented using 2.8 fb -1 of data and two different approaches to cuts. No significant excess is seen in the di-J/ψ mass spectrum.

  1. Di-J/Ψ Studies, Level 3 Tracking and the D0 Run IIb Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Vint, Philip John [Imperial College, London (United Kingdom)

    2010-02-01

    The D0 detector underwent an upgrade to its silicon vertex detector and triggering systems during the transition from Run IIa to Run IIb to maximize its ability to fully exploit Run II at the Fermilab Tevatron. This thesis describes improvements made to the tracking and vertexing algorithms used by the high level trigger in both Run IIa and Run IIb, as well as a search for resonant di-J/Ψ states using both Run IIa and Run IIb data. Improvements made to the tracking and vertexing algorithms during Run IIa included the optimization of the existing tracking software to reduce overall processing time and the certification and testing of a new software release. Upgrades made to the high level trigger for Run IIb included the development of a new tracking algorithm and the inclusion of the new Layer 0 silicon detector into the existing software. The integration of Layer 0 into the high level trigger has led to an improvement in the overall impact parameter resolution for tracks of ~50%. The development of a new parameterization method for finding the error associated to the impact parameter of tracks returned by the high level tracking algorithm, in association with the inclusion of Layer 0, has led to improvements in vertex resolution of ~4.5 μm. A previous search in the di-J/Ψ channel revealed a unpredicted resonance at ~13.7 GeV/c2. A confirmation analysis is presented using 2.8 fb-1 of data and two different approaches to cuts. No significant excess is seen in the di-J/Ψ mass spectrum.

  2. Platelet half-life in patients with primary hyperlipoproteinemia type IIa, IIb, and IV according to Fredrickson with and without clinical signs of atherosclerosis

    Energy Technology Data Exchange (ETDEWEB)

    Jaeger, E; Sinzinger, H; Widhalm, K; Kaliman, J; Hoefer, R [Vienna Univ. (Austria). 2. Medizinische Klinik; Ludwig Boltzmann-Institut fuer Nuklearmedizin, Vienna (Austria); Vienna Univ. (Austria). Kinderklinik; Vienna Univ. (Austria). Kardiologische Klinik)

    1982-09-01

    It is generally accepted that platelet half-life is shortened in atherosclerotic vascular diseases. Concerning changes due to hyperlipoproteinemia (HLP), however, there exist only few data. Therefore, we examined the platelet-half life in 60 patients with recently discovered HLP type IIa, IIb and IV according to Fredrickson before treatment in comparison to 60 controls. 33 of the HLP-patients had no clinical symptoms of angiopathy. 27 patients suffered from peripheral vascular disease or from coronary heart disease as verified by angiography. The labelling of autologous platelets was performed with 100..mu..Ci of /sup 111/Indium-oxine-sulfate at 37/sup 0/C for 5 minutes. The mean labelling efficiency was 90%, the recovery after 2 hours about 70%. Serum lipoproteins were estimated by means of ultracentrifugation and polyanionprecipitation according to Lipid Research Clinic Methods. In the patients with HLP platelet half-life was significantly shortened in comparison to the control group (p < 0.01). These changes were most pronounced in patients with HLP-type IIa and with atherosclerotic lesions, respectively. In patients with HLP-type IIa a very close correlation could be demonstrated between platelet half-life and LDL-cholesterol (r = -0.72; p < 0.001) as well as total cholesterol (r = -0.73; p < 0.001). These data prove that in HLP in-vivo platelet function as measured by platelet survival is significantly influenced even before the occurrence of clinically relevant symptoms of atherosclerosis.

  3. Platelet glycoprotein IIb/IIIa polymorphism HPA-3 b/b is associated with increased risk of ischemic stroke in patients under 60 years of age.

    Science.gov (United States)

    Duan, Hao; Cai, Yan; Sun, Xiaojiang

    2012-01-01

    The role of genetic risk factors in ischemic stroke is unclear. Platelet glycoprotein IIb/IIIa (GpIIb-IIIa) has been implicated in the pathogenesis of ischemic stroke. We sought to evaluate the relationship between the GpIIb/IIIa complex gene polymorphism and ischemic stroke. We investigated the association of the GpIIb/IIIa complex gene polymorphism with stroke risk in 306 patients with acute ischemic stroke and 266 control subjects by determining the GpIIb and GpIIIa genotype from leukocyte DNA by polymerase chain reaction (PCR) followed by FokI and ScrFI digestion, respectively. Compared with controls, more patients presented with coronary heart disease, hypertension, smoking history, and diabetes. In addition, the patients had higher levels of cholesterol and glucose compared with the control subjects. All donors in the GpIIIa (n=572) group expressed the GpIIIa PlA1 (HPA-1 aa) phenotype. There were no significant differences between the HPA-3 genotype (GpIIb) patient distribution (aa=39.9%, ab=41.4%, bb=28.7%) and healthy control subjects (aa=36.1%, ab=35.0%, bb=28.9%) (P=0.580). Among study participants ischemic stroke >2-fold (P=0.008). The GpIIb Ile/Ser843 gene polymorphism is associated with ischemic stroke among young and middle-aged adults (ischemic stroke.

  4. The Effect of Type and Volume Fraction (Vf) of Steel Fiber on the Mechanical Properties of Self-Compacting Concrete

    DEFF Research Database (Denmark)

    Ghanbarpour, S.; Mazaheripour, H.; Mirmoradi, S. H.

    2010-01-01

    is to investigate the effects of type and volume fraction of steel fiber on the compressive strength, split tensile strength, flexural strength and modulus of elasticity of steel fiber reinforced self-compacting concrete (SFRSCC). Design/methodology/approach – For this purpose, Micro wire and Wave type steel fibers......Purpose – Self-compacting concrete (SCC) offers several economic and technical benefits; the use of steel fibers extends its possibilities. Steel fibers bridge cracks, retard their propagation, and improve several characteristics and properties of the SCC. The purpose of this paper...... – It was found that, inclusion of steel fibers significantly affect the split tensile and flexural strength of SCC accordance with type and vf. Besides, mathematical expressions were developed to estimate the flexural, modulus of elasticity and split tensile strength of SFRSCCs regarding of compressive strength...

  5. Regulation of an antisense RNA with the transition of neonatal to IIb myosin heavy chain during postnatal development and hypothyroidism in rat skeletal muscle.

    Science.gov (United States)

    Pandorf, Clay E; Jiang, Weihua; Qin, Anqi X; Bodell, Paul W; Baldwin, Kenneth M; Haddad, Fadia

    2012-04-01

    Postnatal development of fast skeletal muscle is characterized by a transition in expression of myosin heavy chain (MHC) isoforms, from primarily neonatal MHC at birth to primarily IIb MHC in adults, in a tightly coordinated manner. These isoforms are encoded by distinct genes, which are separated by ∼17 kb on rat chromosome 10. The neonatal-to-IIb MHC transition is inhibited by a hypothyroid state. We examined RNA products [mRNA, pre-mRNA, and natural antisense transcript (NAT)] of developmental and adult-expressed MHC genes (embryonic, neonatal, I, IIa, IIx, and IIb) at 2, 10, 20, and 40 days after birth in normal and thyroid-deficient rat neonates treated with propylthiouracil. We found that a long noncoding antisense-oriented RNA transcript, termed bII NAT, is transcribed from a site within the IIb-Neo intergenic region and across most of the IIb MHC gene. NATs have previously been shown to mediate transcriptional repression of sense-oriented counterparts. The bII NAT is transcriptionally regulated during postnatal development and in response to hypothyroidism. Evidence for a regulatory mechanism is suggested by an inverse relationship between IIb MHC and bII NAT in normal and hypothyroid-treated muscle. Neonatal MHC transcription is coordinately expressed with bII NAT. A comparative phylogenetic analysis also suggests that bII NAT-mediated regulation has been a conserved trait of placental mammals for most of the eutherian evolutionary history. The evidence in support of the regulatory model implicates long noncoding antisense RNA as a mechanism to coordinate the transition between neonatal and IIb MHC during postnatal development.

  6. Maximum mass ratio of AM CVn-type binary systems and maximum white dwarf mass in ultra-compact X-ray binaries

    Directory of Open Access Journals (Sweden)

    Arbutina Bojan

    2011-01-01

    Full Text Available AM CVn-type stars and ultra-compact X-ray binaries are extremely interesting semi-detached close binary systems in which the Roche lobe filling component is a white dwarf transferring mass to another white dwarf, neutron star or a black hole. Earlier theoretical considerations show that there is a maximum mass ratio of AM CVn-type binary systems (qmax ≈ 2/3 below which the mass transfer is stable. In this paper we derive slightly different value for qmax and more interestingly, by applying the same procedure, we find the maximum expected white dwarf mass in ultra-compact X-ray binaries.

  7. Filtration behavior of organic substance through a compacted bentonite

    International Nuclear Information System (INIS)

    Kanaji, Mariko; Kuno, Yoshio; Yui, Mikazu

    1999-07-01

    Filtration behavior of organic substance through a compacted bentonite was investigated. Na-type bentonite containing 30wt% of quartz sand was compacted in a column and the dry density was adjusted to be 1.6 g/cm 3 . Polyacrylic acid solution (including three types of polyacrylic acid, average molecular weight 2,100, 15,000 and 450,000) was prepared and was passed through the compacted bentonite. Molecular weight distributions of polyacrylic acid in the effluent solution were analysed by GPC (Gel Permeation Chromatography). A batch type experiment was also carried out in order to examine a sorption behavior of these organic substances onto the surfaces of grains of the bentonite. The results indicated that the smaller size polyacrylic acid (molecular weight < 100,000) was passed through the compacted bentonite. On the other hand, the larger size polyacrylic acid (molecular weight ≥100,000) was mostly filtrated by the compacted bentonite. The batch type sorption tests clarified that the polyacrylic acid did not sorb onto the surfaces of minerals constituting the bentonite. Therefore it was suggested that the larger size molecules (≥100,000) of organic substances could be predominantly filtrated by the microstructure of the compacted bentonite. (author)

  8. Radiation therapy alone in the treatment of cervix cancer stages IIB and IIB. Results from Hospital Mario Gatti, Pontificia Universidade Catolica de Campinas

    International Nuclear Information System (INIS)

    Ferrigno, Robson; Oliveira Faria, Sergio Luis Campos de

    1995-01-01

    From September 1989 to December 1992, 178 patients with cervix cancer were treated with radiation therapy alone, being 81 stage IIIB patients were randomized according to the number of intracavitary brachytherapy insertion realized after external irradiation. Of these, 34 were treated with two intracavitary insertion (group A) and 47 with one insertion (group B). Among stage IIIB patients, 54 were treated with one intracavitary insertion after external irradiation (group C) and 47 with external irradiation alone as they had no geometrical condition for intracavitary insertion (group D). There were no statistical difference in 50 months disease free survival among patients stage IIB treated with one or two intracavitary insertion, 72,3% and 70.6% respectively (P=0,711). The 50 months disease free survival were better in patients stage IIIB treated with external irradiation followed by one intracavitary insertion, compared with those treated with external irradiation alone, 51,8% and 30,2% respectively (P=0,007). This series suggests that there is no difference in the treatment of stage IIB cervix cancer with one or two intracavitary insertion. Among stage IIIB patients, the worse result of those treated with external irradiation alone was probably due to the unfavorable prognostic factors, as they were excluded for brachytherapy because they showed no geometrical condition for intracavitary insertion and larger tumor volume. (author)

  9. Two CRM protein subfamilies cooperate in the splicing of group IIB introns in chloroplasts.

    Science.gov (United States)

    Asakura, Yukari; Bayraktar, Omer Ali; Barkan, Alice

    2008-11-01

    Chloroplast genomes in angiosperms encode approximately 20 group II introns, approximately half of which are classified as subgroup IIB. The splicing of all but one of the subgroup IIB introns requires a heterodimer containing the peptidyl-tRNA hydrolase homolog CRS2 and one of two closely related proteins, CAF1 or CAF2, that harbor a recently recognized RNA binding domain called the CRM domain. Two CRS2/CAF-dependent introns require, in addition, a CRM domain protein called CFM2 that is only distantly related to CAF1 and CAF2. Here, we show that CFM3, a close relative of CFM2, associates in vivo with those CRS2/CAF-dependent introns that are not CFM2 ligands. Mutant phenotypes in rice and Arabidopsis support a role for CFM3 in the splicing of most of the introns with which it associates. These results show that either CAF1 or CAF2 and either CFM2 or CFM3 simultaneously bind most chloroplast subgroup IIB introns in vivo, and that the CAF and CFM subunits play nonredundant roles in splicing. These results suggest that the expansion of the CRM protein family in plants resulted in two subfamilies that play different roles in group II intron splicing, with further diversification within a subfamily to accommodate multiple intron ligands.

  10. Stabilization of compactible waste

    International Nuclear Information System (INIS)

    Franz, E.M.; Heiser, J.H. III; Colombo, P.

    1990-09-01

    This report summarizes the results of series of experiments performed to determine the feasibility of stabilizing compacted or compactible waste with polymers. The need for this work arose from problems encountered at disposal sites attributed to the instability of this waste in disposal. These studies are part of an experimental program conducted at Brookhaven National Laboratory (BNL) investigating methods for the improved solidification/stabilization of DOE low-level wastes. The approach taken in this study was to perform a series of survey type experiments using various polymerization systems to find the most economical and practical method for further in-depth studies. Compactible dry bulk waste was stabilized with two different monomer systems: styrene-trimethylolpropane trimethacrylate (TMPTMA) and polyester-styrene, in laboratory-scale experiments. Stabilization was accomplished by wetting or soaking compactible waste (before or after compaction) with monomers, which were subsequently polymerized. Three stabilization methods are described. One involves the in-situ treatment of compacted waste with monomers in which a vacuum technique is used to introduce the binder into the waste. The second method involves the alternate placement and compaction of waste and binder into a disposal container. In the third method, the waste is treated before compaction by wetting the waste with the binder using a spraying technique. A series of samples stabilized at various binder-to-waste ratios were evaluated through water immersion and compression testing. Full-scale studies were conducted by stabilizing two 55-gallon drums of real compacted waste. The results of this preliminary study indicate that the integrity of compacted waste forms can be readily improved to ensure their long-term durability in disposal environments. 9 refs., 10 figs., 2 tabs

  11. Type IIB Ileosigmoid knotting: a case report

    Directory of Open Access Journals (Sweden)

    Ajak Makor

    2018-02-01

    Full Text Available Ileosigmoid knotting is a rare cause of acute intestinal obstruction. It is more common in Africans and Asians than in white populations and it is more prevalent in males than in females with a ratio of 14:1. It is classified into four types (I, II, III and IV with further extra two subtypes of A and B where type A is the most common presentation. Preoperative diagnosis is a challenge to the frontline doctors in the accidents and emergency departments; especially with limited diagnostic tools. Ultrasonography may be misleading in most of the cases due to the similarity of the disease with other causes of acute abdomen, especially acute appendicitis. Clinical presentation of an unprecedented intestinal obstruction with constant upper to mid-abdominal quadrant pain associated with mild to moderate abdominal distension contrary to the severe abdominal distension in sigmoid volvulus are the hallmarks that can help the surgical team to reach an accurate and early diagnosis preoperatively to avoid the devastating ischemia and gangrene in case of delay.

  12. Variation in one residue associated with the metal ion-dependent adhesion site regulates αIIbβ3 integrin ligand binding affinity.

    Directory of Open Access Journals (Sweden)

    Joel Raborn

    Full Text Available The Asp of the RGD motif of the ligand coordinates with the β I domain metal ion dependent adhesion site (MIDAS divalent cation, emphasizing the importance of the MIDAS in ligand binding. There appears to be two distinct groups of integrins that differ in their ligand binding affinity and adhesion ability. These differences may be due to a specific residue associated with the MIDAS, particularly the β3 residue Ala(252 and corresponding Ala in the β1 integrin compared to the analogous Asp residue in the β2 and β7 integrins. Interestingly, mutations in the adjacent to MIDAS (ADMIDAS of integrins α4β7 and αLβ2 increased the binding and adhesion abilities compared to the wild-type, while the same mutations in the α2β1, α5β1, αVβ3, and αIIbβ3 integrins demonstrated decreased ligand binding and adhesion. We introduced a mutation in the αIIbβ3 to convert this MIDAS associated Ala(252 to Asp. By combination of this mutant with mutations of one or two ADMIDAS residues, we studied the effects of this residue on ligand binding and adhesion. Then, we performed molecular dynamics simulations on the wild-type and mutant αIIbβ3 integrin β I domains, and investigated the dynamics of metal ion binding sites in different integrin-RGD complexes. We found that the tendency of calculated binding free energies was in excellent agreement with the experimental results, suggesting that the variation in this MIDAS associated residue accounts for the differences in ligand binding and adhesion among different integrins, and it accounts for the conflicting results of ADMIDAS mutations within different integrins. This study sheds more light on the role of the MIDAS associated residue pertaining to ligand binding and adhesion and suggests that this residue may play a pivotal role in integrin-mediated cell rolling and firm adhesion.

  13. Orbifolds of M-theory and type II string theories in two dimensions

    International Nuclear Information System (INIS)

    Roy, S.

    1997-01-01

    We consider several orbifold compactifications of M-theory and theircorresponding type II duals in two space-time dimensions. In particular, we show that while the orbifold compactification of M-theory on T 9 /J 9 is dual to the orbifold compactification of type IIB string theory on T 8 /I 8 , the same orbifold T 8 /I 8 of type IIA string theory is dual to M-theory compactified on a smooth product manifold K3 x T 5 . Similarly, while the orbifold compactification of M-theory on (K3 x T 5 )/σ. J 5 is dual to the orbifold compactification of type IIB string theory on (K3 x T 4 )/σ.I 4 , the same orbifold of type IIA string theory is dual to the orbifold T 4 x (K3 x S 1 )/σ.J 1 of M-theory. The spectrum of various orbifold compactifications of M-theory and type II string theories on both sides are compared giving evidence in favor of these duality conjectures. We also comment on a connection between the Dasgupta-Mukhi-Witten conjecture and the Dabholkar-Park-Sen conjecture for the six-dimensional orbifold models of type IIB string theory and M-theory. (orig.)

  14. Crystallization of Enzyme IIB of the Cellobiose-specific Phosphotransferase System of Escherichia coli

    NARCIS (Netherlands)

    van Montfort, Robert; Pijning, Tjaard; Kalk, Kornelis; Schuurman-Wolters, Gea K.; Reizer, Jonathan; Safer Jr., Milton H.; Robillard, George; Dijkstra, Bauke W.

    1994-01-01

    Crystals of enzyme IIB of the cellobiose-specific phosphotransferase system have been obtained from 15% polyethylene glycol 4000 using both streak-seeding and macroseeding techniques at 4°. Crystals were grown with the hanging drop method of vapour diffusion. Addition of 2-propanol and

  15. Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.

    Science.gov (United States)

    Zhu, Jieqing; Choi, Won-Seok; McCoy, Joshua G; Negri, Ana; Zhu, Jianghai; Naini, Sarasija; Li, Jihong; Shen, Min; Huang, Wenwei; Bougie, Daniel; Rasmussen, Mark; Aster, Richard; Thomas, Craig J; Filizola, Marta; Springer, Timothy A; Coller, Barry S

    2012-03-14

    An integrin found on platelets, α(IIb)β(3) mediates platelet aggregation, and α(IIb)β(3) antagonists are effective antithrombotic agents in the clinic. Ligands bind to integrins in part by coordinating a magnesium ion (Mg(2+)) located in the β subunit metal ion-dependent adhesion site (MIDAS). Drugs patterned on the integrin ligand sequence Arg-Gly-Asp have a basic moiety that binds the α(IIb) subunit and a carboxyl group that coordinates the MIDAS Mg(2+) in the β(3) subunits. They induce conformational changes in the β(3) subunit that may have negative consequences such as exposing previously hidden epitopes and inducing the active conformation of the receptor. We recently reported an inhibitor of α(IIb)β(3) (RUC-1) that binds exclusively to the α(IIb) subunit; here, we report the structure-based design and synthesis of RUC-2, a RUC-1 derivative with a ~100-fold higher affinity. RUC-2 does not induce major conformational changes in β(3) as judged by monoclonal antibody binding, light scattering, gel chromatography, electron microscopy, and a receptor priming assay. X-ray crystallography of the RUC-2-α(IIb)β(3) headpiece complex in 1 mM calcium ion (Ca(2+))/5 mM Mg(2+) at 2.6 Å revealed that RUC-2 binds to α(IIb) the way RUC-1 does, but in addition, it binds to the β(3) MIDAS residue glutamic acid 220, thus displacing Mg(2+) from the MIDAS. When the Mg(2+) concentration was increased to 20 mM, however, Mg(2+) was identified in the MIDAS and RUC-2 was absent. RUC-2's ability to inhibit ligand binding and platelet aggregation was diminished by increasing the Mg(2+) concentration. Thus, RUC-2 inhibits ligand binding by a mechanism different from that of all other α(IIb)β(3) antagonists and may offer advantages as a therapeutic agent.

  16. A new compactness type topological property | Zhao | Quaestiones ...

    African Journals Online (AJOL)

    By a gauge on a topological space we shall mean a mapping that assigns each element in the space an open neighbourhood. We investigate some topological properties which can be characterized using gauges. The main property we will consider is the gauge compactness. Some problems and possible future work are ...

  17. A comparison between the pressure-lag model and the rate-type model for the prediction of reservoir compaction and surface subsidence

    Energy Technology Data Exchange (ETDEWEB)

    Smits, R.M.M.; De Waal, J.A.

    1988-06-01

    A theoretical study has been carried out to investigate whether the nonlinear compaction behavior of sandstone reservoirs, which has been reported for most well-documented field cases, can be explained by pressure lags in interbedding and/or neighboring low-permeability (shale) layers. On the basis of the results obtained, it is concluded that pressure-lag effects in normally encountered production scenarios cannot account for these nonlinearities, even under worst-case conditions. Therefore, the nonlinear field-compaction behavior must be caused by rate effects in the sandstone reservoir rock itself. This is supported by the fact that a rate-type compaction model recently introduced does indeed give a good description of the observed field behavior.

  18. Soil susceptibility to compaction under use conditions in southern Brazil

    Directory of Open Access Journals (Sweden)

    Michael Mazurana

    Full Text Available ABSTRACT The degree of soil compaction is intensified by its inadequate management, compaction being variable depending on soil type since even under identical management conditions, different types have different abilities to withstand load. The objective of this study was to evaluate the susceptibility to compaction of different classes of soils under no-tillage (NT croping system compared to the original condition. Thus, i soils with the same source material have distinct resistance to compression with increased NT adoption time; ii the most sensitive indicators of this change are the ratios mass:volume and volume:volume and; iii there is a relationship between resistance and compaction susceptibility with the amount and type of oxide. Soil samples were collected in areas under NT and under natural condition in order to assess the impact imposed by the NT on the attributes density and porosity, precompression stress and compressibility index and relate them to the oxide type of, and content in, the soils under study. The results show that the density and macroporosity were those most affected by the NT agricultural use, regardless of soil type, that is, its dynamic is related more to soil use and less to mineralogical characteristics. The soil resistance and compaction susceptibility were higher in soil developed in basalt, followed by those developed in sandstone and granite. Both the organic matter content and type and concentration of iron oxides were related to the soil resistance and susceptibility to compaction.

  19. An evaluation of canal curvature at the apical one third in type II mesial canals of mandibular molars

    Directory of Open Access Journals (Sweden)

    Hye-Rim Yun

    2012-05-01

    Full Text Available Objectives The purpose of this study was to evaluate the buccolingual curvature at the apical one third in type II mesial canals of mandibular molars using the radius and angle of curvature. Materials and Methods Total 100 mandibular molars were selected. Following an endodontic access in the teeth, their distal roots were removed. #15 H- or K-files (Dentsply Maillefer were inserted into the mesiobuccal and mesiolingual canals of the teeth. Radiographs of the teeth were taken for the proximal view. Among them, type II canals were selected and divided into two subgroups, IIa and IIb. In type IIa, two separate canals merged into one canal before reaching the apex and in type IIb, two separate canals merged into one canal within the apical foramen. The radius and angle of curvature of specimens were examined. Results In type II, mean radius of curvature in mesiolingual and mesiobuccal canals were 2.82 mm and 3.58 mm, respectively. The radius of the curvature of mesiolingual canals were significantly smaller than that of mesiobuccal canals in type II, and especially in type IIa. However, there were no statistically significant differences in radius of curvature between mesiobuccal and mesiolingual canals in type IIb and there were no significant differences in angle of curvature between type IIa and IIb. Conclusion In this study, type II mesial canals of mandibular molars showed severe curvature in the proximal view. Especially, mesiolingual canals of type IIa had more abrupt curvature than mesiobuccal canals at the apical one third.

  20. Deep Compaction Control of Sandy Soils

    Directory of Open Access Journals (Sweden)

    Bałachowski Lech

    2015-02-01

    Full Text Available Vibroflotation, vibratory compaction, micro-blasting or heavy tamping are typical improvement methods for the cohesionless deposits of high thickness. The complex mechanism of deep soil compaction is related to void ratio decrease with grain rearrangements, lateral stress increase, prestressing effect of certain number of load cycles, water pressure dissipation, aging and other effects. Calibration chamber based interpretation of CPTU/DMT can be used to take into account vertical and horizontal stress and void ratio effects. Some examples of interpretation of soundings in pre-treated and compacted sands are given. Some acceptance criteria for compaction control are discussed. The improvement factors are analysed including the normalised approach based on the soil behaviour type index.

  1. Airborne gamma-ray spectrometer and magnetometer survey: Indian Wells, Texas. Final report. Detail area, Volume IIB

    International Nuclear Information System (INIS)

    Volume IIB contains appendices for: flight line maps; geology maps; explanation of geologic legend; flight line/geology maps; radiometric contour maps; magnetic contour maps; geochemical factor analysis maps

  2. Extremely compact formulas for the Fourier transform of a product of two-centre Slater-type orbitals

    International Nuclear Information System (INIS)

    Vukovic, T; Dmitrovic, S

    2010-01-01

    A compact formula for the Fourier transform of a product of Slater-type orbitals on different centres is derived. The integral is reduced to a finite one-dimensional integration over non-oscillatory hypergeometric functions of type 1 F 2 (x;y;z). The formula is valid for all quantum numbers and does not involve the reduced Bessel functions that are usually used to evaluate these integrals. Reduced formulas are calculated for some special directions in the reciprocal space. Also, some useful identities for the Fourier transforms of a product of Slater-type orbitals with correlated sets of parameters are obtained. In order to illustrate simple and efficient use of the presented results, we have applied them to graphene.

  3. Continued evaluation of compact heat exchangers for OTEC evaluation. Final report

    Energy Technology Data Exchange (ETDEWEB)

    McGowan, J.G.

    1979-10-01

    The objectives of this work investigating the applicability of compact plate heat type heat exchangers to OTEC power systems were: (1) an analytical and experimental evaluation of the performance characteristics of compact heat exchangers using ammonia as the working fluid operating under the entire range of OTEC system conditions; and (2) an evaluation of the applicable manufacturing processes, maintenance requirements, and arrangement concepts for large-scale compact OTEC heat exchangers with specific emphasis on total economics. The work was carried out to establish the applicability of compact plate type heat exchangers to OTEC power systems and to provide: (1) experimental verification of predicted performance (heat transfer and fluid flow) under OTEC operating conditions (using NH/sub 3/); (2) provide initial performance data for several desirable plate type OTEC heat exchanger panels; (3) provide test apparatus for continued experimental testing of OTEC compact heat exchanger panels; and (4) provide design information on applicable manufacturing processes maintenance requirements and arrangement concepts for plate type heat exchangers.

  4. Comparison of cDNA-derived protein sequences of the human fibronectin and vitronectin receptor α-subunits and platelet glycoprotein IIb

    International Nuclear Information System (INIS)

    Fitzgerald, L.A.; Poncz, M.; Steiner, B.; Rall, S.C. Jr.; Bennett, J.S.; Phillips, D.R.

    1987-01-01

    The fibronectin receptor (FnR), the vitronectin receptor (VnR), and the platelet membrane glycoprotein (GP) IIb-IIIa complex are members of a family of cell adhesion receptors, which consist of noncovalently associated α- and β-subunits. The present study was designed to compare the cDNA-derived protein sequences of the α-subunits of human FnR, VnR, and platelet GP IIb. cDNA clones for the α-subunit of the FnR (FnR/sub α/) were obtained from a human umbilical vein endothelial (HUVE) cell library by using an oligonucleotide probe designed from a peptide sequence of platelet GP IIb. cDNA clones for platelet GP IIb were isolated from a cDNA expression library of human erythroleukemia cells by using antibodies. cDNA clones of the VnR α-subunit (VnR/sub α/) were obtained from the HUVE cell library by using an oligonucleotide probe from the partial cDNA sequence for the VnR/sub α/. Translation of these sequences showed that the FNR/sub α/, the VnR/sub α/, and GP IIb are composed of disulfide-linked large (858-871 amino acids) and small (137-158 amino acids) chains that are posttranslationally processed from a single mRNA. A single hydrophobic segment located near the carboxyl terminus of each small chain appears to be a transmembrane domain. The large chains appear to be entirely extracellular, and each contains four repeated putative Ca 2+ -binding domains of about 30 amino acids that have sequence similarities to other Ca 2+ -binding proteins. The identity among the protein sequences of the three receptor α-subunits ranges from 36.1% to 44.5%, with the Ca 2+ -binding domains having the greatest homology. These proteins apparently evolved by a process of gene duplication

  5. Distribution of flux vacua around singular points in Calabi-Yau moduli space

    International Nuclear Information System (INIS)

    Eguchi, Tohru; Tachikawa, Yuji

    2006-01-01

    We study the distribution of type-IIB flux vacua in the moduli space near various singular loci, e.g. conifolds, ADE singularities on P 1 , Argyres-Douglas point etc, using the Ashok-Douglas density det (R+ω). We find that the vacuum density is integrable around each of them, irrespective of the type of the singularities. We study in detail an explicit example of an Argyres-Douglas point embedded in a compact Calabi-Yau manifold

  6. Synergistic effect of signaling from receptors of soluble platelet agonists and outside-in signaling in formation of a stable fibrinogen-integrin αIIbβ3-actin cytoskeleton complex.

    Science.gov (United States)

    Budnik, Ivan; Shenkman, Boris; Savion, Naphtali

    2015-01-01

    Thrombus formation in the injured vessel wall is a highly complex process involving various blood-born components that go through specific temporal and spatial changes as observed by intravital videomicroscopy. Platelets bind transiently to the developing thrombus and may either become stably incorporated into or disengage from the thrombus. The aim of the present study was to reveal the processes involved in the formation of a stable thrombus. Platelet-rich plasma and washed platelets were studied by the aggregometer. The aggregate stability was challenged by eptifibatide. Platelet Triton-insoluble fraction was prepared and the actin and αIIb content in the cytoskeleton was analyzed by western blot. Maximal actin polymerization is achieved 1min after platelet activation while maximal αIIbβ3-actin cytoskeleton association requires 5 to 10min of activation and fibrinogen-mediated platelet-to-platelet bridging. Thus, actin polymerization is dependent on platelet activation and requires neither αIIbβ3 integrin occupation nor platelet aggregation. Formation of a stable aggregate requires platelet activation for more than 1min, complete increase in actin cytoskeleton fraction and partial association of αIIbβ3 with the actin cytoskeleton. However, direct αIIbβ3 activation is not sufficient for cytoskeleton complex formation. Thus, stable αIIbβ3-fibrinogen interaction, representing stable aggregate, is achieved after more than 1min agonist activation, involving inside-out and outside-in signaling but not after direct integrin activation, involving only outside-in signaling. Formation of a stable fibrinogen-αIIbβ3-actin cytoskeleton complex is the result of the combined effect of platelet stimulation by soluble agonists, activation of αIIbβ3, fibrinogen binding and platelet-to-platelet bridging. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Muscle hypertrophy and fast fiber type conversions in heavy resistance-trained women.

    Science.gov (United States)

    Staron, R S; Malicky, E S; Leonardi, M J; Falkel, J E; Hagerman, F C; Dudley, G A

    1990-01-01

    Twenty-four women completed a 20-week heavy-resistance weight training program for the lower extremity. Workouts were twice a week and consisted of warm-up exercises followed by three sets each of full squats, vertical leg presses, leg extensions, and leg curls. All exercises were performed to failure using 6-8 RM (repetition maximum). Weight training caused a significant increase in maximal isotonic strength (1 RM) for each exercise. After training, there was a decrease in body fat percentage (p less than 0.05), and an increase in lean body mass (p less than 0.05) with no overall change in thigh girth. Biopsies were obtained before and after training from the superficial portion of the vastus lateralis muscle. Sections were prepared for histological and histochemical examination. Six fiber types (I, IC, IIC, IIA, IIAB, and IIB) were distinguished following routine myofibrillar adenosine triphosphatase histochemistry. Areas were determined for fiber types I, IIA, and IIAB + IIB. The heavy-resistance training resulted in significant hypertrophy of all three groups: I (15%), IIA (45%), and IIAB + IIB (57%). These data are similar to those in men and suggest considerable hypertrophy of all major fiber types is also possible in women if exercise intensity and duration are sufficient. In addition, the training resulted in a significant decrease in the percentage of IIB with a concomitant increase in IIA fibers, suggesting that strength training may lead to fiber conversions.

  8. Self-Compacting Concrete in Precast Elements Industry

    Directory of Open Access Journals (Sweden)

    Corneliu Bob

    2005-01-01

    Full Text Available In this paper the authors present information about the Self-Compacting Concrete and experimental results regarding the use of them into precast element industry. This type of concrete does not require vibration for placing and compaction; it is able to flow under its own weight, completely filling formwork and achieving full compaction, even in the presence of congested reinforcement. The experimental programme has take into account two prestressed beams which were prefabricated and tested on a special stands. The beams of Self-Compacting Concrete with the length of 24 m were prepared at „Beton-Star” Kft, Kecsekenet, Hungary, and used at the CASCO, Satu-Mare.

  9. Long branch-chains of amylopectin with B-type crystallinity in rice seed with inhibition of starch branching enzyme I and IIb resist in situ degradation and inhibit plant growth during seedling development : Degradation of rice starch with inhibition of SBEI/IIb during seedling development.

    Science.gov (United States)

    Pan, Ting; Lin, Lingshang; Wang, Juan; Liu, Qiaoquan; Wei, Cunxu

    2018-01-08

    Endosperm starch provides prime energy for cereal seedling growth. Cereal endosperm with repression of starch branching enzyme (SBE) has been widely studied for its high resistant starch content and health benefit. However, in barley and maize, the repression of SBE changes starch component and amylopectin structure which affects grain germination and seedling establishment. A high resistant starch rice line (TRS) has been developed through inhibiting SBEI/IIb, and its starch has very high resistance to in vitro hydrolysis and digestion. However, it is unclear whether the starch resists in situ degradation in seed and influences seedling growth after grain germination. In this study, TRS and its wild-type rice cultivar Te-qing (TQ) were used to investigate the seedling growth, starch property changes, and in situ starch degradation during seedling growth. The slow degradation of starch in TRS seed restrained the seedling growth. The starch components including amylose and amylopectin were simultaneously degraded in TQ seeds during seedling growth, but in TRS seeds, the amylose was degraded faster than amylopectin and the amylopectin long branch-chains with B-type crystallinity had high resistance to in situ degradation. TQ starch was gradually degraded from the proximal to distal region of embryo and from the outer to inner in endosperm. However, TRS endosperm contained polygonal, aggregate, elongated and hollow starch from inner to outer. The polygonal starch similar to TQ starch was completely degraded, and the other starches with long branch-chains of amylopectin and B-type crystallinity were degraded faster at the early stage of seedling growth but had high resistance to in situ degradation during TRS seedling growth. The B-type crystallinity and long branch-chains of amylopectin in TRS seed had high resistance to in situ degradation, which inhibited TRS seedling growth.

  10. Ceramographic Examinations of Irradiated AGR-1 Fuel Compacts

    Energy Technology Data Exchange (ETDEWEB)

    Paul Demkowicz; Scott Ploger; John Hunn

    2012-05-01

    The AGR 1 experiment involved irradiating 72 cylindrical fuel compacts containing tri-structural isotropic (TRISO)-coated particles to a peak burnup of 19.5% fissions per initial metal atom with no in-pile failures observed out of almost 300,000 particles. Five irradiated AGR 1 fuel compacts were selected for microscopy that span a range of irradiation conditions (temperature, burnup, and fast fluence). These five compacts also included all four TRISO coating variations irradiated in the AGR experiment. The five compacts were cross-sectioned both transversely and longitudinally, mounted, ground, and polished after development of careful techniques for preserving particle structures against preparation damage. Approximately 40 to 80 particles within each cross section were exposed near enough to mid-plane for optical microscopy of kernel, buffer, and coating behavior. The microstructural analysis focused on kernel swelling and porosity, buffer densification and fracture, debonding between the buffer and inner pyrolytic carbon (IPyC) layers, and fractures in the IPyC and SiC layers. Three basic particle morphologies were established according to the extent of bonding between the buffer and IPyC layers: complete debonding along the interface (Type A), no debonding along the interface (Type B), and partial debonding (Type AB). These basic morphologies were subdivided according to whether the buffer stayed intact or fractured. The resulting six characteristic morphologies were used to classify particles within each cross section, but no spatial patterns were clearly observed in any of the cross-sectional morphology maps. Although positions of particle types appeared random within compacts, examining a total of 830 classified particles allowed other relationships among morphological types to be established.

  11. Ceramographic Examinations of Irradiated AGR-1 Fuel Compacts

    International Nuclear Information System (INIS)

    Demkowicz, Paul; Ploger, Scott; Hunn, John

    2012-01-01

    The AGR 1 experiment involved irradiating 72 cylindrical fuel compacts containing tri-structural isotropic (TRISO)-coated particles to a peak burnup of 19.5% fissions per initial metal atom with no in-pile failures observed out of almost 300,000 particles. Five irradiated AGR 1 fuel compacts were selected for microscopy that span a range of irradiation conditions (temperature, burnup, and fast fluence). These five compacts also included all four TRISO coating variations irradiated in the AGR experiment. The five compacts were cross-sectioned both transversely and longitudinally, mounted, ground, and polished after development of careful techniques for preserving particle structures against preparation damage. Approximately 40 to 80 particles within each cross section were exposed near enough to mid-plane for optical microscopy of kernel, buffer, and coating behavior. The microstructural analysis focused on kernel swelling and porosity, buffer densification and fracture, debonding between the buffer and inner pyrolytic carbon (IPyC) layers, and fractures in the IPyC and SiC layers. Three basic particle morphologies were established according to the extent of bonding between the buffer and IPyC layers: complete debonding along the interface (Type A), no debonding along the interface (Type B), and partial debonding (Type AB). These basic morphologies were subdivided according to whether the buffer stayed intact or fractured. The resulting six characteristic morphologies were used to classify particles within each cross section, but no spatial patterns were clearly observed in any of the cross-sectional morphology maps. Although positions of particle types appeared random within compacts, examining a total of 830 classified particles allowed other relationships among morphological types to be established.

  12. Differential impacts of clinical variables and 5-fluorouracil-based adjuvant chemotherapy on 5-year disease-free survival of patients with stage IIa and IIb colon cancer

    Directory of Open Access Journals (Sweden)

    Yi-Hung Kuo

    2018-01-01

    Conclusion: Different predictors of DFS were observed in stage IIa and IIb colon cancer; adjuvant chemotherapy could provide a survival benefit for patients with stage IIb colon cancer who have one of the four factors that were studied in our hospital-based analysis.

  13. Wavelet Types Comparison for Extracting Iris Feature Based on Energy Compaction

    Science.gov (United States)

    Rizal Isnanto, R.

    2015-06-01

    Human iris has a very unique pattern which is possible to be used as a biometric recognition. To identify texture in an image, texture analysis method can be used. One of method is wavelet that extract the image feature based on energy. Wavelet transforms used are Haar, Daubechies, Coiflets, Symlets, and Biorthogonal. In the research, iris recognition based on five mentioned wavelets was done and then comparison analysis was conducted for which some conclusions taken. Some steps have to be done in the research. First, the iris image is segmented from eye image then enhanced with histogram equalization. The features obtained is energy value. The next step is recognition using normalized Euclidean distance. Comparison analysis is done based on recognition rate percentage with two samples stored in database for reference images. After finding the recognition rate, some tests are conducted using Energy Compaction for all five types of wavelets above. As the result, the highest recognition rate is achieved using Haar, whereas for coefficients cutting for C(i) < 0.1, Haar wavelet has a highest percentage, therefore the retention rate or significan coefficient retained for Haaris lower than other wavelet types (db5, coif3, sym4, and bior2.4)

  14. Searching for Compact Radio Sources Associated with UCH ii Regions

    Energy Technology Data Exchange (ETDEWEB)

    Masqué, Josep M.; Trinidad, Miguel A.; Rodríguez-Rico, Carlos A. [Departamento de Astronomía, Universidad de Guanajuato, Apdo. Postal 144, 36000 Guanajuato, México (Mexico); Rodríguez, Luis F.; Kurtz, Stan; Loinard, Laurent [Instituto de Radioastronomía y Astrofísica, Universidad Nacional Autónoma de México, Morelia 58089, México (Mexico); Dzib, Sergio A. [Max Planck Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn (Germany)

    2017-02-10

    Ultra-compact (UC)H ii regions represent a very early stage of massive star formation. The structure and evolution of these regions are not yet fully understood. Interferometric observations showed in recent years that compact sources of uncertain nature are associated with some UCH ii regions. To examine this, we carried out VLA 1.3 cm observations in the A configuration of selected UCH ii regions in order to report additional cases of compact sources embedded in UCH ii regions. With these observations, we find 13 compact sources that are associated with 9 UCH ii regions. Although we cannot establish an unambiguous nature for the newly detected sources, we assess some of their observational properties. According to the results, we can distinguish between two types of compact sources. One type corresponds to sources that are probably deeply embedded in the dense ionized gas of the UCH ii region. These sources are photoevaporated by the exciting star of the region and will last for 10{sup 4}–10{sup 5} years. They may play a crucial role in the evolution of the UCH ii region as the photoevaporated material could replenish the expanding plasma and might provide a solution to the so-called lifetime problem of these regions. The second type of compact sources is not associated with the densest ionized gas of the region. A few of these sources appear resolved and may be photoevaporating objects such as those of the first type, but with significantly lower mass depletion rates. The remaining sources of this second type appear unresolved, and their properties are varied. We speculate on the similarity between the sources of the second type and those of the Orion population of radio sources.

  15. Inner-shell photoionization of group-IIB atoms

    International Nuclear Information System (INIS)

    Kutzner, M.; Tidwell, C.; Vance, S.E.; Radojevic, V.

    1994-01-01

    Total and partial photoionization cross sections, branching ratios, and angular-distribution asymmetry parameters for inner subshells (nl,l≥2) of the group-IIB elements zinc, cadmium, and mercury have been calculated in both the relativistic random-phase approximation and the relativistic random-phase approximation modified to include relaxation. Comparisons are made between the results of the two theoretical methods and with experiment where available. The present theoretical results for the 3d inner-shell photoionization of zinc are not in accord with experiment. We confirm previous work [S. L. Carter and H. P. Kelly, J. Phys. B 11, 2467 (1978)] which demonstrated that relaxation is an important effect in photoionization of the 4d subshell of atomic cadmium. It is also found that the inclusion of relaxation effects resolves a discrepancy between theory and experiment for the 4f inner-shell photoionization of atomic mercury

  16. Group IIB-VIA semiconductor oxide cluster ions

    Science.gov (United States)

    Jayasekharan, Thankan

    2018-05-01

    Metal oxide cluster ions, MnOm± (M = Zn, Cd) and HgnOm- of various stoichiometry have been generated from solid IIB-VIA semiconductor oxides targets, (ZnO(s), CdO(s), and HgO(s)) by using pulse laser desorption ionization time of flight mass spectrometry with a laser of λ = 355 nm. Analysis of mass spectral data indicates the formation of stoichiometric cluster ions viz., (ZnO)n=1-30+ and (CdO)n=1-40+ along with -O bound anions, (ZnO)n=1-30O-, (CdO)n=1-40O- and (HgO)n=1-36O- from their respective solids. Further, metal oxoanions such as ZnOn=2,3-, CdOn=2,3,6-, and HgOn=2,3,6,7- have also been noted signifying the higher coordination ability of both Cd and Hg with O/O2/O3 species.

  17. Structure-activity relationships of an antimicrobial peptide plantaricin s from two-peptide class IIb bacteriocins.

    Science.gov (United States)

    Soliman, Wael; Wang, Liru; Bhattacharjee, Subir; Kaur, Kamaljit

    2011-04-14

    Class IIb bacteriocins are ribosomally synthesized antimicrobial peptides comprising two different peptides synergistically acting in equal amounts for optimal potency. In this study, we demonstrate for the first time potent (nanomolar) antimicrobial activity of a representative class IIb bacteriocin, plantaricin S (Pls), against four pathogenic gram-positive bacteria, including Listeria monocytogenes. The structure-activity relationships for Pls were studied using activity assays, circular dichroism (CD), and molecular dynamics (MD) simulations. The two Pls peptides and five Pls derived fragments were synthesized. The CD spectra of the Pls and selected fragments revealed helical conformations in aqueous 2,2,2-trifluoroethanol. The MD simulations showed that when the two Pls peptides are in antiparallel orientation, the helical regions interact and align, mediated by strong attraction between conserved GxxxG/AxxxA motifs. The results strongly correlate with the antimicrobial activity suggesting that helix-helix alignment of the two Pls peptides and interaction between the conserved motifs are crucial for interaction with the target cell membrane.

  18. On four-derivative terms in IIB Calabi-Yau orientifold reductions

    Energy Technology Data Exchange (ETDEWEB)

    Weissenbacher, Matthias [Kavli Institute for the Physics and Mathematics of the Universe, University of Tokyo,Kashiwa-no-ha 5-1-5, 277-8583 (Japan)

    2017-04-11

    We perform a Kaluza-Klein reduction of IIB supergravity including purely gravitational α{sup ′3}-corrections on a Calabi-Yau threefold, and perform the orientifold projection accounting for the presence of O3/O7-planes. We consider infinitesimal Kähler deformations of the Calabi-Yau background and derive the complete set of four-derivative couplings quadratic in these fluctuations coupled to gravity. In particular, we find four-derivative couplings of the Kähler moduli fields in the four-dimensional effective supergravity theory, which are referred to as friction couplings in the context of inflation.

  19. New supersymmetric AdS4 type II vacua

    International Nuclear Information System (INIS)

    Tsimpis, D.

    2010-01-01

    We review the supersymmetric AdS 4 x w M 6 backgrounds of type IIA/IIB supergravity constructed in[1]. In type IIA the supersymmetry is N=2, and the six-dimensional internal space is locally an S 2 bundle over a four-dimensional Kaehler-Einstein base; in IIB the internal space is the direct product of a circle and a five-dimensional squashed Sasaki-Einstein manifold. These backgrounds do not contain any sources, all fluxes (including the Romans mass in IIA) are generally non-zero, and the dilaton and warp factor are non-constant. The IIA solutions include the massive deformations of the IIA reduction of the eleven-dimensional AdS 4 x Y p,q solutions, and had been predicted to exist on the basis of the AdS 4 /CFT 3 correspondence. (Abstract Copyright [2010], Wiley Periodicals, Inc.)

  20. Compact, Lightweight Servo-Controllable Brakes

    Science.gov (United States)

    Lovchik, Christopher S.; Townsend, William; Guertin, Jeffrey; Matsuoka, Yoky

    2010-01-01

    Compact, lightweight servo-controllable brakes capable of high torques are being developed for incorporation into robot joints. A brake of this type is based partly on the capstan effect of tension elements. In a brake of the type under development, a controllable intermediate state of torque is reached through on/off switching at a high frequency.

  1. Effect of material parameters on the compactibility of backfill materials

    International Nuclear Information System (INIS)

    Keto, P.; Kuula-Vaeisaenen, P.; Ruuskanen, J.

    2006-05-01

    The effect of different parameters on compactibility of mixture of bentonite and ballast as well as Friedland-clay was studied in laboratory with two different types of compaction tests. The material parameters varied were grain size distribution of the ballast material, grain shape, water ratio and bentonite content (15/30%). The other parameters varied were salinity of the mixing water, mixing process and compaction method and energy. Ballast materials with varying grain size distributions were produced from Olkiluoto mica-gneiss with different type of crushing processes. In addition, sand was chosen for ballast material due to its uniform grain size distribution and rounded grain shape. The maximum grain size of the ballast materials was between 5-10 mm. When comparing the compactibility of ballast materials, the highest dry densities were gained for ballast materials with graded grain size distribution. The compaction behaviour of the tested bentonite ballast mixtures is dominated by the bentonite content. The other parameters varied did not have significant effect on the compactibility of the mixtures with bentonite content of 30%. This can be explained with the amount of bentonite that is higher than what is needed to fill up the volume between the ballast grains. The results gained with the two different compaction tests are comparable. Both the bentonite/ballast mixtures and the Friedland clay behaved similarly when compacted with three different compaction pressures (180, 540 and 980 kPa). (orig.)

  2. Progress of compact Marx generators high power microwave source

    International Nuclear Information System (INIS)

    Liu Jinliang; Fan Xuliang; Bai Guoqiang; Cheng Xinbing

    2012-01-01

    The compact Marx generators, which can operate at a certain repetition frequency with small size, light weight, and high energy efficiency, are widely used in narrowband, wideband and ultra-wideband high power microwave (HPM) sources. This type of HPM source based on compact Marx generators is a worldwide research focus in recent years, and is important trend of development. The developments of this type of HPM source are described systemically in this paper. The output parameters and structural characteristics are reviewed, and the trends of development are discussed. This work provides reference and evidence for us to master the status of the HPM source based on compact Marx generators correctly and to explore its technical routes scientifically. (authors)

  3. Investigation of pressing of molybdenum powder compacts

    International Nuclear Information System (INIS)

    Mymrin, S.A.; Kuznetsov, V.Eh.; Yampol'skij, M.L.; Leonov, S.A.; Mikhridinov, R.M.; Korzukhin, V.A.

    1990-01-01

    Results of an experimental investigation into pressing of compacts of MCh type molybdenum powders using the industrial equipment are presented. To measure the density of powder molybdenum billets a radioisotopic density meter with cesium-137 is used as radioactive gamma radiation source. The dependence of the produced billet density on the specific compacting pressure at different values of the powder bulk density is ascertained

  4. Analysis of laboratory compaction methods of roller compacted concrete

    Science.gov (United States)

    Trtík, Tomáš; Chylík, Roman; Bílý, Petr; Fládr, Josef

    2017-09-01

    Roller-Compacted Concrete (RCC) is an ordinary concrete poured and compacted with machines typically used for laying of asphalt road layers. One of the problems connected with this technology is preparation of representative samples in the laboratory. The aim of this work was to analyse two methods of preparation of RCC laboratory samples with bulk density as the comparative parameter. The first method used dynamic compaction by pneumatic hammer. The second method of compaction had a static character. The specimens were loaded by precisely defined force in laboratory loading machine to create the same conditions as during static rolling (in the Czech Republic, only static rolling is commonly used). Bulk densities obtained by the two compaction methods were compared with core drills extracted from real RCC structure. The results have shown that the samples produced by pneumatic hammer tend to overestimate the bulk density of the material. For both compaction methods, immediate bearing index test was performed to verify the quality of compaction. A fundamental difference between static and dynamic compaction was identified. In static compaction, initial resistance to penetration of the mandrel was higher, after exceeding certain limit the resistance was constant. This means that the samples were well compacted just on the surface. Specimens made by pneumatic hammer actively resisted throughout the test, the whole volume was uniformly compacted.

  5. The Rapid Formation of Localized Compaction Bands Under Hydrostatic Load Leading to Pore-pressure Transients in Compacting Rocks

    Science.gov (United States)

    Faulkner, D.; Leclere, H.; Bedford, J. D.; Behnsen, J.; Wheeler, J.

    2017-12-01

    , brittle propagation occurs. In nature, this type of compaction behaviour might result in a mechanism to produce pulses of pore pressure within porous rocks which might have a significant effect on the deformation behaviour at depth.

  6. Peat compaction in deltas : implications for Holocene delta evolution

    NARCIS (Netherlands)

    van Asselen, S.

    2010-01-01

    Many deltas contain substantial amounts of peat, which is the most compressible soil type. Therefore, peat compaction potentially leads to high amounts of subsidence in deltas. The main objective of this research was to quantify subsidence due to peat compaction in Holocene fluvial-deltaic settings

  7. Concept of safe tank-type water cooled and moderated reactor with HTGR microparticle fuel compacts

    International Nuclear Information System (INIS)

    Gol'tsev, A.O.; Kukharkin, N.E.; Mosevitskij, I.S.; Ponomarev-Stepnoj, N.N.; Popov, S.V.; Udyanskij, Yu.N.; Tsibul'skij, V.F.

    1993-01-01

    Concept of safe tank-type water-cooled and moderated reactor on the basis of HTGR fuel microparticles which enable to avoid environment contamination with radioactive products under severe accidents, is proposed. Results of neutron-physical and thermal-physical studies of water cooled and moderated reactor with HTGR microparticle compacts are presented. Characteristics of two reactors with thermal power of 500 and 1500 MW are indicated within the concept frames. The reactor behaviour under severe accident connected with complete loss of water coolant is considered. It is shown that under such an accident the fission products release from fuel microparticles does not occur

  8. The G2 spinorial geometry of supersymmetric IIB backgrounds

    International Nuclear Information System (INIS)

    Gran, U; Gutowski, J; Papadopoulos, G

    2006-01-01

    We solve the Killing spinor equations of supersymmetric IIB backgrounds which admit one supersymmetry and the Killing spinor has stability subgroup G 2 in Spin(9, 1) x U(1). We find that such backgrounds admit a timelike Killing vector field and the geometric structure of the spacetime reduces from Spin(9, 1) x U(1) to G 2 . We determine the type of G 2 structure that the spacetime admits by computing the covariant derivatives of the spacetime forms associated with the Killing spinor bilinears. We also solve the Killing spinor equations of backgrounds with two supersymmetries and Spin(7) x R 8 -invariant spinors, and four supersymmetries with SU(4) x R 8 - and with G 2 -invariant spinors. We show that the Killing spinor equations factorize in two sets, one involving the geometry and the 5-form flux, and the other the 3-form flux and the scalars. In the Spin(7) x R 8 and SU(4) x R 8 cases, the spacetime admits a parallel null vector field and so the spacetime metric can be locally described in terms of Penrose coordinates adapted to the associated rotation free, null, geodesic congruence. The transverse space of the congruence is a Spin(7) and a SU(4) holonomy manifold, respectively. In the G 2 case, all the fluxes vanish and the spacetime is the product of a three-dimensional Minkowski space with a holonomy G 2 manifold

  9. How to Make Eccentricity Cycles in Stratigraphy: the Role of Compaction

    Science.gov (United States)

    Liu, W.; Hinnov, L.; Wu, H.; Pas, D.

    2017-12-01

    Milankovitch cycles from astronomically driven climate variations have been demonstrated as preserved in cyclostratigraphy throughout geologic time. These stratigraphic cycles have been identified in many types of proxies, e.g., gamma ray, magnetic susceptibility, oxygen isotopes, carbonate content, grayscale, etc. However, the commonly prominent spectral power of orbital eccentricity cycles in stratigraphy is paradoxical to insolation, which is dominated by precession index power. How is the spectral power transferred from precession to eccentricity in stratigraphy? Nonlinear sedimentation and bioturbation have long been identified as players in this transference. Here, we propose that in the absence of bioturbation differential compaction can generate the transference. Using insolation time series, we trace the steps by which insolation is transformed into stratigraphy, and how differential compaction of lithology acts to transfer spectral power from precession to eccentricity. Differential compaction is applied to unique values of insolation, which is assumed to control the type of deposited sediment. High compaction is applied to muds, and progressively lower compaction is applied to silts and sands, or carbonate. Linear differential compaction promotes eccentricity spectral power, but nonlinear differential compaction elevates eccentricity spectral power to dominance and precession spectral power to near collapse as is often observed in real stratigraphy. Keywords: differential compaction, cyclostratigraphy, insolation, eccentricity

  10. Compact stellarators as reactors

    International Nuclear Information System (INIS)

    Lyon, J.F.; Valanju, P.; Zarnstorff, M.C.; Hirshman, S.; Spong, D.A.; Strickler, D.; Williamson, D.E.; Ware, A.

    2001-01-01

    Two types of compact stellarators are examined as reactors: two- and three-field-period (M=2 and 3) quasi-axisymmetric devices with volume-average =4-5% and M=2 and 3 quasi-poloidal devices with =10-15%. These low-aspect-ratio stellarator-tokamak hybrids differ from conventional stellarators in their use of the plasma-generated bootstrap current to supplement the poloidal field from external coils. Using the ARIES-AT model with B max =12T on the coils gives Compact Stellarator reactors with R=7.3-8.2m, a factor of 2-3 smaller R than other stellarator reactors for the same assumptions, and neutron wall loadings up to 3.7MWm -2 . (author)

  11. Large Binocular Telescope/LUCIFER spectroscopy: kinematics of a compact early-type galaxy at z ≃ 1.4

    Science.gov (United States)

    Longhetti, M.; Saracco, P.; Gargiulo, A.; Tamburri, S.; Lonoce, I.

    2014-04-01

    We present a high signal-to-noise ratio (S/N > 10) medium-resolution (R = 2000) Large Binocular Telescope/LUCIFER spectrum of the early-type galaxy (ETG) S2F1-142 at z ≃ 1.4. By means of the CaT line at 8662 Å, we measured its redshift z = 1.386 ± 0.001 and we estimated its velocity dispersion σ v=340^{-60}_{+120} km s-1. Its corresponding virial mass is 3.9 × 1011 M⊙, compatible with the stellar mass estimates obtained assuming initial mass functions (IMFs) less dwarf rich than the Salpeter one. S2F1-142 is a compact galaxy with Re = 3.1 ± 0.2 kpc, i.e. an effective radius more than three times smaller than the average Re of ETGs with the same mass in the local Universe. At the same time, we found local and high-redshift galaxies with a similar mass content and similar effective radius confirming that it is fully consistent with the already available measures of Re and σv both in the local and in the distant Universe. Considering the distribution of Re and σv as a function of the stellar mass content of ETGs, both in the local and in the distant Universe, we noticed that the measured velocity dispersions of the more compact galaxies are on average slightly lower than expected on the basis of their compactness and the virial theorem, suggesting that (i) their dark matter content is lower than in the more diffuse galaxies and/or (ii) their luminosity profiles are steeper than in the more diffuse galaxies and/or (iii) their larger compactness is an apparent effect caused by the overestimate of their stellar mass content (due to bottom lighter IMF and/or systematic affecting the stellar mass estimates).

  12. Intraoperative validation of CT-based lymph nodal levels, sublevels IIa and IIb: Is it of clinical relevance in selective radiation therapy?

    International Nuclear Information System (INIS)

    Levendag, Peter; Gregoire, Vincent; Hamoir, Marc; Voet, Peter; Est, Henrie van der; Heijmen, Ben; Kerrebijn, Jeroen

    2005-01-01

    Purpose: The objectives of this study are to discuss the intraoperative validation of CT-based boundaries of lymph nodal levels in the neck, and in particular the clinical relevance of the delineation of sublevels IIa and IIb in case of selective radiation therapy (RT). Methods and Materials: To validate the radiologically defined level contours, clips were positioned intraoperatively at the level boundaries defined by surgical anatomy. In 10 consecutive patients, clips were placed, at the time of a neck dissection being performed, at the most cranial border of the neck. Anterior-posterior and lateral X-ray films were obtained intraoperatively. Next, in 3 patients, neck levels were contoured on preoperative contrast-enhanced CT scans according to the international consensus guidelines. From each of these 3 patients, an intraoperative CT scan was also obtained, with clips placed at the surgical-anatomy-based level boundaries. The preoperative (CT-based) and intraoperative (surgery-defined) CT scans were matched. Results: Clips placed at the most cranial part of the neck lined up at the caudal part of the transverse process of the cervical vertebra C-I. The posterior border of surgical level IIa (spinal accessory nerve [SAN]) did not match with the posterior border of CT-based level IIa (internal jugular vein [IJV]). Other surgical boundaries and CT-based contours were in good agreement. Conclusions: The cranial border of the neck, i.e., the cranial border of level IIa/IIb, corresponds to the caudal edge of the lateral process of C-I. Except for the posterior border between level IIa and level IIb, a perfect match was observed between the other surgical-clip-identified levels II-V boundaries (surgical-anatomy) and the CT-based delineation contours. It is argued that (1) because of the parotid gland overlapping part of level II, and (2) the frequent infestation of occult metastatic cells in the lymph channels around the IJV, the division of level II into radiologic

  13. Invasive cervical carcinoma (Stages IB-IIB)

    International Nuclear Information System (INIS)

    Sironi, S.; Zanello, A.; Rodighiero, M.G.; Vanzulli, A.; Del Maschio, A.; Taccagni, G.L.; Belloni, C.

    1991-01-01

    In the patients with invasive cervical carcinoma, the accurate assessment of parametrial invasion greatly affects the therapeutic choice between surgery and radiation therapy. As a matter of fact, surgery is usually performed only in the patients with carcinoma confined to the cervix, whereas those with parametrial involvement, or more advanced stages, are treated with radiation therapy. This prospective study was aimed at investigating the comparative adequecy of CT and MR imaging in assessing parametrial status in the patients with invasive cervical cancer. Twenty-one consecutive patients, with histologic diagnosis of cervical carcinoma, were investigated. All of them were clinically considered as having invasive cervical cancer (FIGO stage IB-IIB) and subsequently underwent surgery. In all cases, detailed histology of the parametrium was obtained. Pathological data were compared with CT and MR findings in all cases. As for assessing parametrial involvement by cancer, CT had 62% accuracy, 63% sensitivity, and 60% specificity, versus MR imaging 81% accuracy, 69% sensitivity, and 80% specificify. Therefore, MR imaging appears to be superior to CT in assessing the parametrial status of patients with invasive cervical carcinoma; the method yields valuable information for treatment planning

  14. Application of nanotechnology in self-compacting concrete design

    International Nuclear Information System (INIS)

    Maghsoudi, A. A.; Arabpour Dahooei, F.

    2009-01-01

    In this study, first, different mix design of four types of Self-Compacting Concrete, 1. Self-Compacting Concrete consisted of only nano silica, 2. Self-Compacting Concrete included only micro silica, 3. Self-Compacting Concrete consisted of both micro silica and nano silica and 4. Self-Compacting Concrete without micro silica and nano silica called as control mix, were casted and tested to find out the values of the Slump Flow, L-Box and 7 and 28 days compressive strength. Then, based on the results obtained and as yet there is no universally accepted standard for characterizing of Self-Compacting Concrete, the most suitable four concrete mixes were selected for further investigation of fresh and hardened concrete. For selected mixes, the fresh concrete properties such as values of the Slump Flow, L-Box, V-Funnel, J-Ring and hardened engineering properties such as compressive and flexural strength, shrinkage and swelling values were investigated for three curing conditions at short and long term. The results showed that the engineering properties of Self-Compacting Concrete mixes could not be improved by adding only nano silica. However, a satisfactory behavior can be achieved using micro silica in the Self-Compacting Concrete mixes. However, by adding both micro silica and nano silica to the Self-Compacting Concrete mixtures, the best effect on the engineering properties was reported while comparing to the control mixes.

  15. Isolation and characterization of major histocompatibility complex class IIB genes from the nurse shark.

    Science.gov (United States)

    Bartl, S; Weissman, I L

    1994-01-04

    The major histocompatibility complex (MHC) contains a set of linked genes which encode cell surface proteins involved in the binding of small peptide antigens for their subsequent recognition by T lymphocytes. MHC proteins share structural features and the presence and location of polymorphic residues which play a role in the binding of antigens. In order to compare the structure of these molecules and gain insights into their evolution, we have isolated two MHC class IIB genes from the nurse shark, Ginglymostoma cirratum. Two clones, most probably alleles, encode proteins which differ by 13 amino acids located in the putative antigen-binding cleft. The protein structure and the location of polymorphic residues are similar to their mammalian counterparts. Although these genes appear to encode a typical MHC protein, no T-cell-mediated responses have been demonstrated in cartilaginous fish. The nurse shark represents the most phylogenetically primitive organism in which both class IIA [Kasahara, M., Vazquez, M., Sato, K., McKinney, E.C. & Flajnik, M.F. (1992) Proc. Natl. Acad. Sci USA 89, 6688-6692] and class IIB genes, presumably encoding the alpha/beta heterodimer, have been isolated.

  16. An integral design concept for ecological self-compacting concrete

    NARCIS (Netherlands)

    Hunger, M.

    2010-01-01

    This Thesis addresses an alternative design concept for Self-Compacting Concrete (SCC). SCC is a special type of concrete with superior workability, which flows and compacts in all corners of a formwork just by the influence of gravity. Introduced to the concrete world in the late 1980s, SCC has

  17. Discriminating neutrino mass models using Type-II see-saw formula

    Indian Academy of Sciences (India)

    though a fuller analysis needs the full matrix form when all terms are present. This is followed by the normal hierarchical model (Type [III]) and inverted hierarchical model with opposite CP phase (Type [IIB]). γ ≃ 10−2 for both of them. Our main results on neutrino masses and mixings in Type-II see-saw formula are presented ...

  18. Project of compact accelerator for cancer proton therapy

    International Nuclear Information System (INIS)

    Picardi, L.; Ronsivalle, C.; Vignati, A.

    1995-04-01

    The status of the sub-projetc 'Compact Accelerator' in the framework of the Hadrontherapy Project leaded by Prof. Amaldi is described. Emphasis is given to the reasons of the use of protons for radiotherapy applications, to the results of the preliminary design studies of four types of accelerators as possible radiotherapy dedicated 'Compact Accelerator' and to the scenario of the fonts of financial resources

  19. Towards natural inflation in string theory

    International Nuclear Information System (INIS)

    Ben-Dayan, Ido; Pedro, Francisco G.; Westphal, Alexander

    2014-07-01

    We provide type IIB string embeddings of two axion variants of natural inflation. We use a combination of RR 2 form axions as the inflaton field and have its potential generated by non perturbative effects in the superpotential. Besides giving rise to inflation, the models developed take into account the stabilization of the compact space, both in the KKLT and large volume scenario regimes, an essential condition for any semi-realistic model of string inflation.

  20. Compact Spreader Schemes

    Energy Technology Data Exchange (ETDEWEB)

    Placidi, M.; Jung, J. -Y.; Ratti, A.; Sun, C.

    2014-07-25

    This paper describes beam distribution schemes adopting a novel implementation based on low amplitude vertical deflections combined with horizontal ones generated by Lambertson-type septum magnets. This scheme offers substantial compactness in the longitudinal layouts of the beam lines and increased flexibility for beam delivery of multiple beam lines on a shot-to-shot basis. Fast kickers (FK) or transverse electric field RF Deflectors (RFD) provide the low amplitude deflections. Initially proposed at the Stanford Linear Accelerator Center (SLAC) as tools for beam diagnostics and more recently adopted for multiline beam pattern schemes, RFDs offer repetition capabilities and a likely better amplitude reproducibility when compared to FKs, which, in turn, offer more modest financial involvements both in construction and operation. Both solutions represent an ideal approach for the design of compact beam distribution systems resulting in space and cost savings while preserving flexibility and beam quality.

  1. PKL-tests, test series IIB (end of blowdown). Vol. 2

    International Nuclear Information System (INIS)

    Umminger, K.; Mandl, R.; Nopper, H.; Siemens AG Unternehmensbereich KWU, Erlangen

    1987-01-01

    As part of the federally subsidized research project 1500 287/A0, the system behavior of a 1300 MWe pressurized water reactor (PWR) was investigated during the depressurization phase (end-of-blowdown, EOB), as well as during the refill and reflood phases of a loss of coolant accident involving a large break in the reactor coolant loop. Appropriate modifications to the system and supplementary instrumentation have made it possible to simulate the EOB (as of 26 bar), the refill phase and reflood phase in sequence. This report includes a detailed description of the instrumentation and the data acquisition system used in Test Series PKL IIB. (orig.) With 6 refs., 2 tabs., 60 figs [de

  2. Investigation of alteration behaviour of compacted bentonite contracted with carbon steel for 10 years

    International Nuclear Information System (INIS)

    Suyama, Tadahiro; Ueno, Kenichi; Sasamoto, Hiroshi

    2008-03-01

    To evaluate long term behavior of corrosion for carbon steel in compacted bentonite, and to evaluate long term stability of bentonite, corrosion experiments were conducted using synthetic sea water and synthetic groundwater at 50 and 80degC for 10 years under anaerobic atmosphere. In the present study, the samples of compacted bentonite after experiments were investigated to understand the alteration behavior of bentonite by iron-bentonite interactions. Results were summarized below. Iron generated by corrosion of carbon steel was migrated into compacted bentonite further in the synthetic seawater case than in the synthetic groundwater case. Result of TEM observation for the sample of synthetic sea water case at 80degC showed that the original layer structure for clay minerals was maintained and the layer distance was about 12[A] which was similar to the layer distance of normal 2:1 smectite. Thus, it was suggested that there was no change in smectite before and after experiments. Iron generated by corrosion of carbon steel was migrated into compacted bentonite in anaerobic condition case but scarcely migrated in aerobic condition case. Results of EPMA analysis indicated that the maximum migration depth of iron in compacted bentonite was about 0.2 mm for sample in synthetic sea water at 80degC under anaerobic condition. Results of XRD analysis for the sample in which iron migration in compacted bentonite was observed showed that there was no corrosion product in compacted bentonite and the structure of clay mineral in bentonite was di-octahedral. Furthermore, the result of XRD analysis under relative humidity controlled condition suggested that the swelling property of sample after experiment was similar to that of initial Na-type smectite. Therefore, it was supposed that the initial Na-type smectite did not change during the experiment. Batch type experiments with different temperature, solutions and duration have been conducted to understand the alteration

  3. Bailout use of platelet glycoprotein IIb-IIIa inhibition during coronary stent implantation: observations from the ESPRIT trial.

    Science.gov (United States)

    Cantor, Warren J; Madan, Mina; O'Shea, J Conor; Chisholm, Robert J; Lui, Henry K; Cohen, David J; Feldman, Robert L; Green, Robert; Hellkamp, Anne S; Kitt, Michael M; Tcheng, James E

    2005-07-01

    Glycoprotein (GP) IIb/IIIa inhibitors are often used as a rescue or bailout therapy to manage complications arising during percutaneous coronary intervention, rather than as prophylactic treatment. We sought to identify the characteristics and outcomes of patients requiring bailout treatment. The ESPRIT trial randomized 2,064 patients to receive eptifibatide or placebo starting immediately before percutaneous coronary intervention (PCI). Bailout therapy was used in 77 patients: 43 (4.2%) randomized to placebo and 34 (3.3%) to eptifibatide (p = 0.3). Bailout therapy for thrombosis was used more often in the placebo group (2.1% versus 1.0%; p = 0.03). Multivariable predictors of bailout included a greater than or equal to 90% stenosis, or visible thrombus on the baseline angiogram, and no aspirin pre-treatment before PCI. However, overall the model predicted bailout poorly (c-index = 0.64). The need for bailout cannot be reliably predicted using baseline characteristics. Patients experiencing complications have poor clinical outcomes despite bailout use of GP IIb/IIIa inhibitors.

  4. Development of compact size penning ion source for compact neutron generator.

    Science.gov (United States)

    Das, Basanta Kumar; Shyam, Anurag

    2008-12-01

    For long-life operation, easy to mount and compact in size penning type ion sources are widely used in different fields of research such as neutron generators, material research, and surface etching. One penning type ion source has been developed in our laboratory. Applying high voltage of 2 kV between two oppositely biased electrodes and using permanent magnet of 500 gauss magnetic field along the axis, we had produced the glow discharge in the plasma region. The performance of this source was investigated using nitrogen gas. Deuterium ions were produced and extracted on the basis of chosen electrodes and the angle of extraction. Using a single aperture plasma electrode, the beam was extracted along the axial direction. The geometry of plasma electrode is an important factor for the efficient extraction of the ions from the plasma ion source. The extracted ion current depends upon the shape of the plasma meniscus. A concave shaped plasma meniscus produces converged ion beam. The convergence of extracted ions is related to the extraction electrode angle. The greater the angle, the more the beam converges. We had studied experimentally this effect with a compact size penning ion source. The detailed comparison among the different extraction geometry and different electrode angle are discussed in this paper.

  5. Type IIA on a compact Calabi-Yau and D=11 supergravity uplift of its orientifold

    International Nuclear Information System (INIS)

    Misra, A.

    2004-01-01

    Using the prescription of K. Hori and C. Vafa for defining period integrals in the Landau-Ginsburg theory for compact Calabi-Yau's, we obtain the Picard-Fuchs equation and the Meijer basis of solutions for the compact Calabi-Yau CY 3 (3,243) expressed as a degree-24 Fermat hypersurface after resolution of the orbifold singularities. The importance of the method lies in the ease with which one can consider the large and small complex structure limits, as well as the ability to get the ''ln''-terms in the periods without having to parametrically differentiate infinite series. We consider in detail the evaluation of the monodromy matrix in the large and small complex structure limits. We also consider the action of the freely acting antiholomorphic involution on D=11 supergravity compactified on CY 3 (3,243) x S 1 and obtain the Kaehler potential for the same in the limit of large volume of the Calabi-Yau. As a by-product, we also give a conjecture for the action of the orientation-reversing antiholomorphic involution on the periods, given its action on the cohomology, using a canonical (co)homology basis. Finally, we also consider showing a null superpotential on the orientifold of type IIA on CY 3 (3,243), having taken care of the orbifold singularities. (Abstract Copyright [2004], Wiley Periodicals, Inc.)

  6. An Active Black Hole in a Compact Dwarf

    Science.gov (United States)

    Kohler, Susanna

    2016-05-01

    A new type of galaxy has just been added to the galaxy zoo: a small, compact, and old elliptical galaxy that shows signs of a monster black hole actively accreting material in its center. What can this unusual discovery tell us about how compact elliptical galaxies form?A New Galactic BeastCompact elliptical galaxies are an extremely rare early-type dwarf galaxy. Consistent with their name, compact ellipticals are small, very compact collections of ancient stars; these galaxies exhibit a high surface brightness and arent actively forming stars.Optical view of the ancient compact elliptical galaxy SDSS J085431.18+173730.5 (center of image) in an SDSS color composite image. [Adapted from Paudel et al. 2016]Most compact ellipticals are found in dense environments, particularly around massive galaxies. This has led astronomers to believe that compact ellipticals might form via the tidal stripping of a once-large galaxy in interactions with another, massive galaxy. In this model, once the original galaxys outer layers are stripped away, the compact inner bulge component would be left behind as a compact elliptical galaxy. Recent discoveries of a few isolated compact ellipticals, however, have strained this model.Now a new galaxy has been found to confuse our classification schemes: the first-ever compact elliptical to also display signs of an active galactic nucleus. Led by Sanjaya Paudel (Korea Astronomy and Space Science Institute), a team of scientists discovered SDSS J085431.18+173730.5 serendipitously in Sloan Digital Sky Survey data. The team used SDSS images and spectroscopy in combination with data from the Canada-France-Hawaii Telescope to learn more about this unique galaxy.Puzzling CharacteristicsSDSS J085431.18+173730.5 presents an interesting conundrum. Ancient compact ellipticals are supposed to be devoid of gas, with no fuel left to trigger nuclear activity. Yet SDSS J085431.18+173730.5 clearly shows the emission lines that indicate active accretion onto

  7. Complementary effects of thienopyridine pretreatment and platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention; results from the ESPRIT trial.

    Science.gov (United States)

    Dery, Jean-Pierre; Campbell, Mark E; Mathias, Jasmine; Pieper, Karen S; Harrington, Robert A; Madan, Mina; Gibson, C Michael; Tolleson, Thaddeus R; O'Shea, J Conor; Tcheng, James E

    2007-07-01

    This analysis sought to investigate the complementary effect of thienopyridine pretreatment and platelet glycoprotein (GP) IIb/IIIa integrin blockade in coronary stent intervention. Definitive evidence supporting combined antiplatelet therapy consisting of thienopyridine pretreatment and GP IIb/IIIa receptor blockade in patients undergoing percutaneous coronary intervention (PCI) with stent implantation is limited. We retrospectively analyzed clinical outcomes by thienopyridine use in the 2,040 patients randomized to eptifibatide or placebo who underwent PCI in the ESPRIT trial. A total of 901 patients received a loading dose of thienopyridine before PCI (group 1), 123 received thienopyridine pretreatment without a loading dose (group 2), and 1,016 were not treated with thienopyridine before PCI (group 3). The composite incidence of death or myocardial infarction at 30 days was significantly lower in group 1 than in groups 2 and 3 combined (OR, 0.71 [95%CI, 0.52-0.99]; P = 0.0417). A similar trend was seen for the composite of death, myocardial infarction, or urgent target vessel revascularization (unadjusted OR, 0.77 [0.57-1.05]; P = 0.1025). After adjusting for baseline characteristics, these differences were no longer significant. No interactions were identified with eptifibatide assignment for any of the group comparisons. Pretreatment with a loading dose of thienopyridine lowers the rate of ischemic complications regardless of treatment with a GP IIb/IIIa inhibitor. Conversely, the efficacy of eptifibatide is maintained whether or not a loading dose of a thienopyridine is administered. Optimal outcomes are achieved in patients receiving thienopyridine pretreatment along with platelet GP IIb/IIIa inhibitor therapy. (c) 2007 Wiley-Liss, Inc.

  8. Effects of compaction pressure and particle shape on the porosity and compression mechanical properties of sintered Ti6Al4V powder compacts for hard tissue implantation.

    Science.gov (United States)

    Güden, Mustafa; Celik, Emrah; Hizal, Alpay; Altindiş, Mustafa; Cetiner, Sinan

    2008-05-01

    Sintered Ti6Al4V powder compacts potentially to be used in implant applications were prepared using commercially available spherical and angular powders (100-200 mum) within the porosity range of 34-54%. Cylindrical green powder compacts were cold compacted at various pressures and then sintered at 1200 degrees C for 2 h. The final percent porosity and mean pore sizes were determined as functions of the applied compaction pressure and powder type. The mechanical properties were investigated through compression testing. Results have shown that yield strength of the powder compacts of 40-42% porosity was comparable with that of human cortical bone. As compared with previously investigated Ti powder compacts, Ti6Al4V powder compacts showed higher strength at similar porosity range. Microscopic observations on the failed compact samples revealed that failure occurred primarily by the separation of interparticle bond regions in the planes 45 degrees to the loading axis. Copyright 2007 Wiley Periodicals, Inc.

  9. The D-instanton and other supersymmetric D-branes in IIB plane-wave string theory

    International Nuclear Information System (INIS)

    Gaberdiel, Matthias R.; Green, Michael B.

    2003-01-01

    A class of D-branes for the type IIB plane-wave background is considered that preserve half the dynamical supersymmetries of the light-cone gauge. The D-branes of this type are the Euclidean (or instantonic) (0,0), (0,4), and (4,0) branes (where (r,s) denotes a brane oriented with r axes in the first four directions transverse to the +, - light-cone, and s axes in the second four directions). Corresponding Lorentzian D-branes are (+,-;0,0), (+,-;0,4), and (+,-;4,0). These are constructed in two ways. The first uses a boundary state formalism which implements appropriate fermionic gluing conditions and the second is based on a direct quantization of the open strings ending on the branes. In distinction to the D-branes considered earlier these have massless world-volume fermions but do not possess kinematical supersymmetries. Cylinder diagrams describing the overlap between a pair of boundary states displaced by some distance are evaluated. The open-string description of this system involves mode frequencies that are, in general, given by irrational solutions to transcendental equations. The closed-string and open-string descriptions are shown to be equivalent by a nontrivial implementation of the S modular transformation. A classical description of the D-instanton (the (0,0) case) in light-cone gauge is also given

  10. Equipoise in the enhanced supression of the platelet IIb/IIIa receptor with integrilin trial (ESPRIT): a critical appraisal.

    Science.gov (United States)

    Mann, Howard; London, Alex John; Mann, Jeffrey

    2005-01-01

    Enhanced Supression of the Platelet IIb/IIIa Receptor with Integrilin Trial (ESPRIT) was a multicenter randomized controlled clinical trial in which participants were randomized between eptifibatide and placebo. A "clinical hold" was initially placed on the trial by the US Food and Drug Administration (FDA), which was concerned about the placebo-only control arm. The hold was lifted after additional information concerning the use of platelet glycoprotein IIb/IIIa inhibitors in clinical practice, derived from a survey of interventional cardiologists, was provided. The trial's principal investigator and colleagues have described how these issues were resolved, and advance a claim of equipoise for the trial. In this critical appraisal we examine the information and arguments proffered in support of the trial design and conclude that they evidence a misunderstanding of equipoise. We believe that a placebo-only control arm was not justified by the information provided by the trialists.

  11. Compact Bell inequalities for multipartite experiments

    OpenAIRE

    Wu, Yu-Chun; Żukowski, Marek; Chen, Jing-Ling; Guo, Guang-Can

    2013-01-01

    A method for construction of the multipartite Clauser-Horne-Shimony-Holt (CHSH) type Bell inequalities, for the case of local binary observables, is presented. The standard CHSH-type Bell inequalities can be obtained as special cases. A unified framework to establish all kinds of CHSH-type Bell inequalities by increasing step by step the number of observers is given. As an application, compact Bell inequalities, for eight observers, involving just four correlation functions are proposed. They...

  12. The Combination of GIS and Biphasic to Better Predict In Vivo Dissolution of BCS Class IIb Drugs, Ketoconazole and Raloxifene.

    Science.gov (United States)

    Tsume, Yasuhiro; Igawa, Naoto; Drelich, Adam J; Amidon, Gregory E; Amidon, Gordon L

    2018-01-01

    The formulation developments and the in vivo assessment of Biopharmaceutical Classification System (BCS) class II drugs are challenging due to their low solubility and high permeability in the human gastrointestinal (GI) tract. Since the GI environment influences the drug dissolution of BCS class II drugs, the human GI characteristics should be incorporated into the in vitro dissolution system to predict bioperformance of BCS class II drugs. An absorptive compartment may be important in dissolution apparatus for BCS class II drugs, especially for bases (BCS IIb) because of high permeability, precipitation, and supersaturation. Thus, the in vitro dissolution system with an absorptive compartment may help predicting the in vivo phenomena of BCS class II drugs better than compendial dissolution apparatuses. In this study, an absorptive compartment (a biphasic device) was introduced to a gastrointestinal simulator. This addition was evaluated if this in vitro system could improve the prediction of in vivo dissolution for BCS class IIb drugs, ketoconazole and raloxifene, and subsequent absorption. The gastrointestinal simulator is a practical in vivo predictive tool and exhibited an improved in vivo prediction utilizing the biphasic format and thus a better tool for evaluating the bioperformance of BCS class IIb drugs than compendial apparatuses. Copyright © 2018. Published by Elsevier Inc.

  13. Radiation therapy for stage IIA and IIB testicular seminoma: peripheral dose calculations and risk assessments

    Science.gov (United States)

    Mazonakis, Michalis; Berris, Theocharris; Lyraraki, Efrossyni; Damilakis, John

    2015-03-01

    This study was conducted to calculate the peripheral dose to critical structures and assess the radiation risks from modern radiotherapy for stage IIA/IIB testicular seminoma. A Monte Carlo code was used for treatment simulation on a computational phantom representing an average adult. The initial treatment phase involved anteroposterior and posteroanaterior modified dog-leg fields exposing para-aortic and ipsilateral iliac lymph nodes followed by a cone-down phase for nodal mass irradiation. Peripheral doses were calculated using different modified dog-leg field dimensions and an extended conventional dog-leg portal. The risk models of the BEIR-VII report and ICRP-103 were combined with dosimetric calculations to estimate the probability of developing stochastic effects. Radiotherapy for stage IIA seminoma with a target dose of 30 Gy resulted in a range of 23.0-603.7 mGy to non-targeted peripheral tissues and organs. The corresponding range for treatment of stage IIB disease to a cumulative dose of 36 Gy was 24.2-633.9 mGy. A dose variation of less than 13% was found by altering the field dimensions. Radiotherapy with the conventional instead of the modern modified dog-leg field increased the peripheral dose up to 8.2 times. The calculated heart doses of 589.0-632.9 mGy may increase the risk for developing cardiovascular diseases whereas the testicular dose of more than 231.9 mGy may lead to a temporary infertility. The probability of birth abnormalities in the offspring of cancer survivors was below 0.13% which is much lower than the spontaneous mutation rate. Abdominoplevic irradiation may increase the lifetime intrinsic risk for the induction of secondary malignancies by 0.6-3.9% depending upon the site of interest, patient’s age and tumor dose. Radiotherapy for stage IIA/IIB seminoma with restricted fields and low doses is associated with an increased morbidity. These data may allow the definition of a risk-adapted follow-up scheme for long

  14. Compact nuclear fuel storage

    International Nuclear Information System (INIS)

    Kiselev, V.V.; Churakov, Yu.A.; Danchenko, Yu.V.; Bylkin, B.K.; Tsvetkov, S.V.

    1983-01-01

    Different constructions of racks for compact storage of spent fuel assemblies (FA) in ''coolin''g pools (CP) of NPPs with the BWR and PWR type reactors are described. Problems concerning nuclear and radiation safety and provision of necessary thermal conditions arising in such rack design are discussed. It is concluded that the problem of prolonged fuel storage at NPPs became Very actual for many countries because of retapdation of the rates of fuel reprocessing centers building. Application of compact storage racks is a promising solution of the problem of intermediate FA storage at NPPs. Such racks of stainless boron steel and with neutron absorbers in the from of boron carbide panels enable to increase the capacity of the present CP 2-2.6 times, and the period of FA storage in them up to 5-10 years

  15. Industrial production of insulators using isostatic compaction method

    Energy Technology Data Exchange (ETDEWEB)

    Drugoveiko, O.P.; Ermolaeva, L.V.; Koren' , M.G.; Kreimer, B.D.; Panichev, G.I.; Ponomarev, A.P.; Rutkovskii, V.N.

    1985-07-01

    The process of shaping ceramic products from powders using isostatic compaction method is finding increasing industrial application. The production of electrical-engineering porcelain using isostatic compaction method is, according to the authors, a promising direction since this method permits one to obtain large and complex shaped products having uniform density distribution. The authors introduce an automatic isostatic compaction line at the ''Proletarii'' Factory for the production of the IOS-110-20000UKhL, T1 type insulators having the described dimensions. According to the technological process developed at the ''Elektrokeramika'' Production Complex, insulators were manufactured on the isostatic compaction line from the G-33 mass. Presspowder having a moisture content of 0.3-0.6% and a particle size of 90-160 micrometers was obtained in a spray dryer using disk spraying. The authors studied saturability by moisture of the powder obtained.

  16. Recent results in the Los Alamos compact torus program

    International Nuclear Information System (INIS)

    Tuszewski, M.; Armstrong, W.T.; Barnes, C.W.

    1983-01-01

    A Compact Toroid is a toroidal magnetic-plasma-containment geometry in which no conductors or vacuum-chamber walls pass through the hole in the torus. Two types of compact toroids are studied experimentally and theoretically at Los Alamos: spheromaks that are oblate in shape and contain both toroidal and poloidal magnetic fields, and field-reversed configurations (FRC) that are very prolate and contain poloidal field only

  17. Mouse Embryo Compaction.

    Science.gov (United States)

    White, M D; Bissiere, S; Alvarez, Y D; Plachta, N

    2016-01-01

    Compaction is a critical first morphological event in the preimplantation development of the mammalian embryo. Characterized by the transformation of the embryo from a loose cluster of spherical cells into a tightly packed mass, compaction is a key step in the establishment of the first tissue-like structures of the embryo. Although early investigation of the mechanisms driving compaction implicated changes in cell-cell adhesion, recent work has identified essential roles for cortical tension and a compaction-specific class of filopodia. During the transition from 8 to 16 cells, as the embryo is compacting, it must also make fundamental decisions regarding cell position, polarity, and fate. Understanding how these and other processes are integrated with compaction requires further investigation. Emerging imaging-based techniques that enable quantitative analysis from the level of cell-cell interactions down to the level of individual regulatory molecules will provide a greater understanding of how compaction shapes the early mammalian embryo. © 2016 Elsevier Inc. All rights reserved.

  18. Near-surface microstructural modification of (Ti,W)(C,N)-based compacts with nitrogen

    International Nuclear Information System (INIS)

    Ucakar, V.; Kral, C.; Lengauer, W.

    2001-01-01

    For developing of functional-gradient hardmetals the interaction of nitrogen with (Ti,W)(C,N)-based compacts was investigated. Hot-pressed (Ti,W)(C,N) compacts as well as sintered compacts of (Ti,W)(C,N)+Co were subjected to sintering and heat treatment at 1200-1500 o C and up to 30 bar N 2 . In (Ti,W)(C,N) compacts four microstructure types were obtained upon reaction with nitrogen. A uniform single-phase (Ti,W)(C,N) forms in samples with a low WC and high TiN content. If medium WC and high TiN/TiC ratio is present a core-rim type structure forms during Ar annealing which remains the same when nitrogen in-diffusion occurs. The third type of microstructure shows sub-micron lamellae of nitrogen-rich fcc phase and WC. This structure forms at increased WC and/or TiC content. If the WC content is increased again a WC layer forms at the outermost surface. Compressive stresses introduced by phase formation/decomposition were obtained for the nitrogen in-diffusion. Sintered (Ti,W)(C,N)+Co compacts were heat treated above and below the eutectic temperature. Above the eutectic temperature compact Ti(C,N) top-layers independent an sample composition were observed. Below the eutectic temperature the microstructure formation is mainly influenced by the sample composition. A Ti(C,N) top-layer forms in materials with a high Ti(C,N) content. Contrary, interaction zones without a layer were obtained in compacts with high WC/Ti(C,N) ratio. Some of these surface modified compacts show surfaces and particle sizes favorable for a cutting tool. (author)

  19. Isolation and characterization of major histocompatibility complex class IIB genes from the nurse shark.

    OpenAIRE

    Bartl, S; Weissman, I L

    1994-01-01

    The major histocompatibility complex (MHC) contains a set of linked genes which encode cell surface proteins involved in the binding of small peptide antigens for their subsequent recognition by T lymphocytes. MHC proteins share structural features and the presence and location of polymorphic residues which play a role in the binding of antigens. In order to compare the structure of these molecules and gain insights into their evolution, we have isolated two MHC class IIB genes from the nurse...

  20. Radiotherapy results of uterine cervix cancer stape IIB : overall survival, prognostic facters, patterns of failure and late complications

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eun Seog; Choi, Doo Ho [Soonchunhyang Univ. College of Medicine, Asan (Korea, Republic of); Huh, Seung Jae [Samsung Medical Center, Sungkyunkwan Univ. College of Medicine, Seoul (Korea, Republic of)

    1998-03-01

    Treatment of choice for uterine cervix cancer stage IIB is radiotherapy. We analyzed survivals, prognostic factors, patterns of failure and complications. This is a retrospective analysis of 167 patients with stage IIB carcinoma of uterine cervix treated with curative external pelvic and high dose rate intracavitary radiotherapy at the Department of Therapeutic Radiology, Soonchunhyang University Hospital from August 1985 to August 1994. All the patients followed up from 3 to 141 months(mean 60 months) and age of patients ranged from 31 to 78 years at presentation(mean : 55 years). Overall complete response rate was 84%. The response rate for squamous cell carcimoma and adenocarcinoma were 86% and 60%, respectively. Overall 5-years survival rate and disease free survival rate was 62 and 59%, respectively. Mass size and treatment response were significant prognostic factors for survival. Pathologic type and parametrial involvement were marginally significants prognostic factors. Local failure was 43 cases, distant metastasis was 14 cases and local failure plus distant metastasis was 3 cases, and most of local failures occurred within 24 months, distant metastasis within 12 months after treatment. Twenty eight(16.8%) patients developed late rectal and urinary complications There were tendency to increasing severity and frequency according to increased fractional dose and total(rectal and bladder) dose. Survival rate was significantly related to tumor size and radiotherapy response. Tumor size should be considered in the clinical staging. To increased survival and local control, clinical trials such as decreasing duration of radiotherapy or addition of chemotherapy is needed. To detect early recurrence, regular follow up after RT is important. Because total rectal and bladder dose affected late complications, meticulous vaginal packing is needed to optimize dose of normal tissues and to decrease late complications.

  1. Compact, low-loss and broadband photonic crystal circulator based on a star-type ferrite rod

    Directory of Open Access Journals (Sweden)

    Xiang Xi

    Full Text Available We propose and investigate a compact, low-loss and broadband circulator based on a star-type ferrite rod in two-dimensional square-lattice photonic crystals. Only one ferrite rod is required to be inserted in our structure. Firstly, the performances of circulator based on the star-type, circle, and square ferrite rod are compared, showing that the circulator with the star-type ferrite rod performs better than the other two ones. And then, based on the star-type ferrite rod circulator, four cases of improvement, in which the background rods around the center ferrite rod are replaced respectively by the backward-triangle, forward-triangle, backward-semicircle, and forward-semicircle rods, are investigated to modulate the coupling between the center magneto-optical micro-cavity and the corresponding waveguides. The results show that, with proper parameters, all the four cases can greatly improve the output properties of the circulator, and different cases have its own advantages. The mechanism behind these improvements is also discussed. Finite-element method is used to calculate the characteristics of the circulator and Nelder-Mead optimization method is employed to obtain the optimized parameters. The ideas presented here are useful for designing broadband, low insertion loss, and high-isolation circulators which have potential application in integrated photonic crystal devices. Keywords: Photonic crystals, Circulator, Magneto-optical material, Photonic crystal waveguides

  2. Development of a compact solar combisystem

    DEFF Research Database (Denmark)

    Thür, Alexander; Furbo, Simon

    2006-01-01

    Within the frame of the project REBUS, “Competitive solar heating systems for residential buildings”, which is financed by Nordic Energy Research, a new type of compact solar combisystem with high degree of prefabrication was developed. A hydraulic and control concept was designed with the goal...

  3. Compactly supported frames for decomposition spaces

    DEFF Research Database (Denmark)

    Nielsen, Morten; Rasmussen, Kenneth Niemann

    2012-01-01

    In this article we study a construction of compactly supported frame expansions for decomposition spaces of Triebel-Lizorkin type and for the associated modulation spaces. This is done by showing that finite linear combinations of shifts and dilates of a single function with sufficient decay in b...

  4. A comparison of compacting and caking behaviour of carbonate-based washing powders

    OpenAIRE

    Leaper, M.C.; Leach, V.; Taylor, P.M.; Prime, D.C.

    2013-01-01

    Two types of sodium carbonate powder produced by spray drying (SD) and dry neutralisation (DN) were studied for their compaction properties using a uniaxial compression tester. Dry neutralised sodium carbonate showed a greater resistance to compression and also produced a weaker compact when compressed to 100kPa. Differential Scanning Calorimetry (DSC) showed that both types of powder were predominantly amorphous in nature. Moisture sorption measurements showed that both powders behaved in a ...

  5. Development of compact D-D neutron generator

    International Nuclear Information System (INIS)

    Das, Basanta Kumar; Das, Rashmita; Shyam, Anurag

    2011-12-01

    In recent years, due to specific features of compact neutron generators, their demand in elemental analysis and detection of the illicit materials has been increased in scientific community. Compact is size, controlled operation and radiation safety like features of neutron generator is suitable for research work with illicit materials. An accelerator based neutron generator can be operated in steady mode as well as in pulse mode. The main embodiment of this type of generator includes ion source, ion acceleration system and target. We are developing such type of neutron generator. This consists of one-in-house developed penning ion source, a single electrode acceleration gap and one deuterated titanium target or virgin titanium target. In this report, we will discuss various physics and technical issues related to the important components of this generator, operation of the generator and neutron detection. (author)

  6. Posttranslational modification of hepatic cytochrome P-450. Phosphorylation of phenobarbital-inducible P-450 forms PB-4 (IIB1) and PB-5 (IIB2) in isolated rat hepatocytes and in vivo

    International Nuclear Information System (INIS)

    Koch, J.A.; Waxman, D.J.

    1989-01-01

    Phosphorylation of hepatic cytochrome P-450 was studied in isolated hepatocytes incubated in the presence of agents known to stimulate protein kinase activity. Incubation of hepatocytes isolated from phenobarbital-induced adult male rats with [ 32 P]orthophosphate in the presence of N 6 , O 2' -dibutyryl-cAMP (diBtcAMP) or glucagon resulted in the phosphorylation of microsomal proteins that are immunoprecipitable by polyclonal antibodies raised to the phenobarbital-induced P-450 form PB-4 (P-450 gene IIB1). Two-dimensional gel electrophoresis revealed that these 32 P-labeled microsomal proteins consist of a mixture of P-450 PB-4 and the closely related P-450 PB-5 (gene IIB2), both of which exhibited heterogeneity in the isoelectric focusing dimension. Phosphorylation of both P-450 forms was markedly enhanced by diBtcAMP at concentrations as low as 5 μM. Phosphoamino acid analysis of the 32 P-labeled P-450 PB-4 + PB-5 immunoprecipitate revealed that these P-450s are phosphorylated on serine in the isolated hepatocytes. Peptide mapping indicated that the site of phosphorylation in hepatocytes is indistinguishable from the site utilized by cAMP-dependent protein kinase in vitro, which was previously identified as serine-128 for the related rabbit protein P-450 LM2. In vitro analyses revealed that phosphorylation of P-450 PB-4 leads to a loss of monooxygenase activity, suggesting that the posttranslational modification of this P-450 enzyme by cAMP-dependent protein kinase may play a role in the modulation of P-450-dependent monooxygenase activity in vivo

  7. EVIDENCE FOR (AND AGAINST) PROGENITOR BIAS IN THE SIZE GROWTH OF COMPACT RED GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Keating, Stephanie K.; Abraham, Roberto G. [Department of Astronomy and Astrophysics, University of Toronto, 50 St. George Street, Toronto, ON M5S 3H4 (Canada); Schiavon, Ricardo [Gemini Observatory, 670 North A' ohoku Place, Hilo, HI 96720 (United States); Graves, Genevieve [Department of Astronomy, University of California, Berkeley, CA 94720 (United States); Damjanov, Ivana [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Yan, Renbin [Department of Physics and Astronomy, University of Kentucky, 505 Rose Street, Lexington, KY 40506-0055 (United States); Newman, Jeffrey [Department of Physics and Astronomy, University of Pittsburgh, 3941 O' Hara Street, Pittsburgh, PA 15260 (United States); Simard, Luc [National Research Council of Canada, 5071 West Saanich Road, Victoria, BC V9E 2E7 (Canada)

    2015-01-01

    Most massive, passive galaxies are compact at high redshifts, but similarly compact massive galaxies are rare in the local universe. The most common interpretation of this phenomenon is that massive galaxies have grown in size by a factor of about five since redshift z = 2. An alternative explanation is that recently quenched massive galaxies are larger (a {sup p}rogenitor bias{sup )}. In this paper, we explore the importance of progenitor bias by looking for systematic differences in the stellar populations of compact early-type galaxies in the DEEP2 survey as a function of size. Our analysis is based on applying the statistical technique of bootstrap resampling to constrain differences in the median ages of our samples and to begin to characterize the distribution of stellar populations in our co-added spectra. The light-weighted ages of compact early-type galaxies at redshifts 0.5 < z < 1.4 are compared to those of a control sample of larger galaxies at similar redshifts. We find that massive compact early-type galaxies selected on the basis of red color and high bulge-to-total ratio are younger than similarly selected larger galaxies, suggesting that size growth in these objects is not driven mainly by progenitor bias, and that individual galaxies grow as their stellar populations age. However, compact early-type galaxies selected on the basis of image smoothness and high bulge-to-total ratio are older than a control sample of larger galaxies. Progenitor bias will play a significant role in defining the apparent size changes of early-type galaxies if they are selected on the basis of the smoothness of their light distributions.

  8. Prediction of abrupt reservoir compaction and surface subsidence due to pore collapse in carbonates

    Energy Technology Data Exchange (ETDEWEB)

    Smits, R.M.M.; de Waal, A.; van Kooten, J.F.C.

    1986-01-01

    A new procedure has been developed to predict the abrupt in-situ compaction and the associated surface subsidence above high-porosity carbonate fields showing pore collapse. The approach is based on an extensive laboratory compaction study in which the effects of carbonate type, porosity, core preparation, pore saturant, horizontal to vertical stress ratio and loading rate on the pore collapse behaviour were investigated. For each carbonate type a trendline was established describing the relationship between the porosity after collapse and the vertical effective stress. This trendline concept, in combination with existing subsidence models, enables reservoir compaction and surface subsidence to be predicted on the basis of wireline porosity logs. Static and dynamic elastic constants were found to be uncorrelated during pore collapse. The position of the trendline depends strongly on carbonate type, pore saturant, loading rate and stress ratio. Therefore procedures are given to derive the correct in-situ trendline from laboratory compaction experiments.

  9. Prediction of abrupt reservoir compaction and surface subsidence caused by pore collapse in carbonates

    Energy Technology Data Exchange (ETDEWEB)

    Smits, R.M.M.; De Waal, J.A.; Van Kootan, J.F.C.

    1988-06-01

    A new procedure has been developed to predict the abrupt in-situ compaction and the associated surface subsidence above high-porosity carbonate fields that show pore collapse. The approach is based on an extensive laboratory compaction study in which the effects of carbonate type, porosity, core preparation, pore saturant, horizontal/vertical stress ratio, and loading rate on pore-collapse behavior were investigated. For a number of carbonate types, a trendline was established that describes the relationship between the porosity after collapse and the vertical effective stress. This trendline concept, in combination with existing subsidence models, enables reservoir compaction and surface subsidence to be predicted on the basis of wireline porosity logs. Static and dynamic elastic constants were found to be uncorrelated during pore collapse. The position of the trendline depends strongly on carbonate type, pore saturant, loading rate, and stress ratio. Therefore, procedures are given to derive the correct in-situ trendline from laboratory compaction experiments.

  10. Specificity of RSG-1.2 peptide binding to RRE-IIB RNA element of HIV-1 over Rev peptide is mainly enthalpic in origin.

    Science.gov (United States)

    Kumar, Santosh; Bose, Debojit; Suryawanshi, Hemant; Sabharwal, Harshana; Mapa, Koyeli; Maiti, Souvik

    2011-01-01

    Rev is an essential HIV-1 regulatory protein which binds to the Rev responsive element (RRE) present within the env gene of HIV-1 RNA genome. This binding facilitates the transport of the RNA to the cytoplasm, which in turn triggers the switch between viral latency and active viral replication. Essential components of this complex have been localized to a minimal arginine rich Rev peptide and stem IIB region of RRE. A synthetic peptide known as RSG-1.2 binds with high binding affinity and specificity to the RRE-IIB than the Rev peptide, however the thermodynamic basis of this specificity has not yet been addressed. The present study aims to probe the thermodynamic origin of this specificity of RSG-1.2 over Rev Peptide for RRE-IIB. The temperature dependent melting studies show that RSG-1.2 binding stabilizes the RRE structure significantly (ΔT(m) = 4.3°C), in contrast to Rev binding. Interestingly the thermodynamic signatures of the binding have also been found to be different for both the peptides. At pH 7.5, RSG-1.2 binds RRE-IIB with a K(a) = 16.2±0.6×10(7) M(-1) where enthalpic change ΔH = -13.9±0.1 kcal/mol is the main driving force with limited unfavorable contribution from entropic change TΔS = -2.8±0.1 kcal/mol. A large part of ΔH may be due to specific stacking between U72 and Arg15. In contrast binding of Rev (K(a) = 3.1±0.4×10(7) M(-1)) is driven mainly by entropy (ΔH = 0 kcal/mol and TΔS = 10.2±0.2 kcal/mol) which arises from major conformational changes in the RNA upon binding.

  11. Supersymmetric AdS3, AdS2 and bubble solutions

    International Nuclear Information System (INIS)

    Gauntlett, Jerome P.; Waldram, Daniel; Kim, Nakwoo

    2007-01-01

    We present new supersymmetric AdS 3 solutions of type IIB supergravity and AdS 2 solutions of D = 11 supergravity. The former are dual to conformal field theories in two dimensions with N = (0, 2) supersymmetry while the latter are dual to conformal quantum mechanics with two supercharges. Our construction also includes AdS 2 solutions of D = 11 supergravity that have non-compact internal spaces which are dual to three-dimensional N = 2 superconformal field theories coupled to point-like defects. We also present some new bubble-type solutions, corresponding to BPS states in conformal theories, that preserve four supersymmetries

  12. Compact complex surfaces with geometric structures related to split quaternions

    International Nuclear Information System (INIS)

    Davidov, Johann; Grantcharov, Gueo; Mushkarov, Oleg; Yotov, Miroslav

    2012-01-01

    We study the problem of existence of geometric structures on compact complex surfaces that are related to split quaternions. These structures, called para-hypercomplex, para-hyperhermitian and para-hyperkähler, are analogs of the hypercomplex, hyperhermitian and hyperkähler structures in the definite case. We show that a compact 4-manifold carries a para-hyperkähler structure iff it has a metric of split signature together with two parallel, null, orthogonal, pointwise linearly independent vector fields. Every compact complex surface admitting a para-hyperhermitian structure has vanishing first Chern class and we show that, unlike the definite case, many of these surfaces carry infinite-dimensional families of such structures. We provide also compact examples of complex surfaces with para-hyperhermitian structures which are not locally conformally para-hyperkähler. Finally, we discuss the problem of non-existence of para-hyperhermitian structures on Inoue surfaces of type S 0 and provide a list of compact complex surfaces which could carry para-hypercomplex structures.

  13. Estimation of Compaction Parameters Based on Soil Classification

    Science.gov (United States)

    Lubis, A. S.; Muis, Z. A.; Hastuty, I. P.; Siregar, I. M.

    2018-02-01

    Factors that must be considered in compaction of the soil works were the type of soil material, field control, maintenance and availability of funds. Those problems then raised the idea of how to estimate the density of the soil with a proper implementation system, fast, and economical. This study aims to estimate the compaction parameter i.e. the maximum dry unit weight (γ dmax) and optimum water content (Wopt) based on soil classification. Each of 30 samples were being tested for its properties index and compaction test. All of the data’s from the laboratory test results, were used to estimate the compaction parameter values by using linear regression and Goswami Model. From the research result, the soil types were A4, A-6, and A-7 according to AASHTO and SC, SC-SM, and CL based on USCS. By linear regression, the equation for estimation of the maximum dry unit weight (γdmax *)=1,862-0,005*FINES- 0,003*LL and estimation of the optimum water content (wopt *)=- 0,607+0,362*FINES+0,161*LL. By Goswami Model (with equation Y=mLogG+k), for estimation of the maximum dry unit weight (γdmax *) with m=-0,376 and k=2,482, for estimation of the optimum water content (wopt *) with m=21,265 and k=-32,421. For both of these equations a 95% confidence interval was obtained.

  14. Compact Q-balls

    Energy Technology Data Exchange (ETDEWEB)

    Bazeia, D., E-mail: bazeia@fisica.ufpb.br [Departamento de Física, Universidade Federal da Paraíba, 58051-970 João Pessoa, PB (Brazil); Losano, L.; Marques, M.A. [Departamento de Física, Universidade Federal da Paraíba, 58051-970 João Pessoa, PB (Brazil); Menezes, R. [Departamento de Ciências Exatas, Universidade Federal da Paraíba, 58297-000 Rio Tinto, PB (Brazil); Departamento de Física, Universidade Federal de Campina Grande, 58109-970 Campina Grande, PB (Brazil); Rocha, R. da [Centro de Matemática, Computação e Cognição, Universidade Federal do ABC, 09210-580 Santo André (Brazil)

    2016-07-10

    In this work we deal with non-topological solutions of the Q-ball type in two space–time dimensions, in models described by a single complex scalar field that engenders global symmetry. The main novelty is the presence of stable Q-balls solutions that live in a compact interval of the real line and appear from a family of models controlled by two distinct parameters. We find analytical solutions and study their charge and energy, and show how to control the parameters to make the Q-balls classically and quantum mechanically stable.

  15. Slurry dispersion state as a parameter to control internal structure of alumina green compact

    Energy Technology Data Exchange (ETDEWEB)

    Saito, M.; Shui, A.; Tanaka, S.; Uchida, N.; Uematsu, K. [Nagaoka Univ. of Technology, Niigata (Japan)

    2002-07-01

    The dispersion state of slurry must be controlled to produce granules with appropriated properties for pressing. In this study dispersion state of alumina slurry is changed to form granules with different morphology, deformation property and packing density, and the influence on the internal structure of green compact are presented. Novel methods applying liquid immersion technique coupled with different type of microscopy were used to characterize the internal structures of green compacts. Two types of granules were obtained: dimpled, hard and dense granule, and spherical, soft and loose granule. The respective internal structures of green compacts were totally different. (orig.)

  16. The mirror transform of type I vacua in six dimensions

    International Nuclear Information System (INIS)

    Sen, A.; Sethi, S.

    1997-01-01

    We study certain compactifications of the type I string on K3. The three topologically distinct choices of gauge bundles for the type I theory are shown to be equivalent to type IIB orientifolds with different choices of background anti-symmetric tensor field flux. Using a mirror transformation we relate these models to orientifolds with fixed seven planes, and without any anti-symmetric tensor field flux. This map allows us to relate these type I vacua to particular six-dimensional F-theory and heterotic string compactifications. (orig.)

  17. Compact Polarimetry Potentials

    Science.gov (United States)

    Truong-Loi, My-Linh; Dubois-Fernandez, Pascale; Pottier, Eric

    2011-01-01

    The goal of this study is to show the potential of a compact-pol SAR system for vegetation applications. Compact-pol concept has been suggested to minimize the system design while maximize the information and is declined as the ?/4, ?/2 and hybrid modes. In this paper, the applications such as biomass and vegetation height estimates are first presented, then, the equivalence between compact-pol data simulated from full-pol data and compact-pol data processed from raw data as such is shown. Finally, a calibration procedure using external targets is proposed.

  18. Are soils in urban ecosystems compacted? A citywide analysis.

    Science.gov (United States)

    Edmondson, Jill L; Davies, Zoe G; McCormack, Sarah A; Gaston, Kevin J; Leake, Jonathan R

    2011-10-23

    Soil compaction adversely influences most terrestrial ecosystem services on which humans depend. This global problem, affecting over 68 million ha of agricultural land alone, is a major driver of soil erosion, increases flood frequency and reduces groundwater recharge. Agricultural soil compaction has been intensively studied, but there are no systematic studies investigating the extent of compaction in urban ecosystems, despite the repercussions for ecosystem function. Urban areas are the fastest growing land-use type globally, and are often assumed to have highly compacted soils with compromised functionality. Here, we use bulk density (BD) measurements, taken to 14 cm depth at a citywide scale, to compare the extent of surface soil compaction between different urban greenspace classes and agricultural soils. Urban soils had a wider BD range than agricultural soils, but were significantly less compacted, with 12 per cent lower mean BD to 7 cm depth. Urban soil BD was lowest under trees and shrubs and highest under herbaceous vegetation (e.g. lawns). BD values were similar to many semi-natural habitats, particularly those underlying woody vegetation. These results establish that, across a typical UK city, urban soils were in better physical condition than agricultural soils and can contribute to ecosystem service provision.

  19. Compaction of FGD-gypsum

    NARCIS (Netherlands)

    Stoop, B.T.J.; Larbi, J.A.; Heijnen, W.M.M.

    1996-01-01

    It is shown that it is possible to produce compacted gypsum with a low porosity and a high strength on a laboratory scale by uniaxial compaction of flue gas desulphurization (FGD-) gypsum powder. Compacted FGD-gypsum cylinders were produced at a compaction pres-sure between 50 and 500 MPa yielding

  20. (U) Influence of Compaction Model Form on Planar and Cylindrical Compaction Geometries

    Energy Technology Data Exchange (ETDEWEB)

    Fredenburg, David A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Carney, Theodore Clayton [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fichtl, Christopher Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ramsey, Scott D. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2018-01-05

    The dynamic compaction response of CeO2 is examined within the frameworks of the Ramp and P-a compaction models. Hydrocode calculations simulating the dynamic response of CeO2 at several distinct pressures within the compaction region are investigated in both planar and cylindrically convergent geometries. Findings suggest additional validation of the compaction models is warranted under complex loading configurations.

  1. SGC Tests for Influence of Material Composition on Compaction Characteristic of Asphalt Mixtures

    Directory of Open Access Journals (Sweden)

    Qun Chen

    2013-01-01

    Full Text Available Compaction characteristic of the surface layer asphalt mixture (13-type gradation mixture was studied using Superpave gyratory compactor (SGC simulative compaction tests. Based on analysis of densification curve of gyratory compaction, influence rules of the contents of mineral aggregates of all sizes and asphalt on compaction characteristic of asphalt mixtures were obtained. SGC Tests show that, for the mixture with a bigger content of asphalt, its density increases faster, that there is an optimal amount of fine aggregates for optimal compaction and that an appropriate amount of mineral powder will improve workability of mixtures, but overmuch mineral powder will make mixtures dry and hard. Conclusions based on SGC tests can provide basis for how to adjust material composition for improving compaction performance of asphalt mixtures, and for the designed asphalt mixture, its compaction performance can be predicted through these conclusions, which also contributes to the choice of compaction schemes.

  2. N-terminal sequence of human leukocyte glycoprotein Mo1: conservation across species and homology to platelet IIb/IIIa.

    Science.gov (United States)

    Pierce, M W; Remold-O'Donnell, E; Todd, R F; Arnaout, M A

    1986-12-12

    Mo1 and gp160-gp93 are two surface membrane glycoprotein heterodimers present on granulocytes and monocytes derived from humans and guinea pigs, respectively. We purified both antigens and found that their alpha subunits had identical N-termini which were significantly homologous to the alpha subunit of the human adhesion platelet glycoprotein IIb/IIIa.

  3. THE EFFECT OF DRY GRANULATION ON THE CONSOLIDATION AND COMPACTION OF CRYSTALLINE LACTOSE

    NARCIS (Netherlands)

    RIEPMA, KA; VROMANS, H; ZUURMAN, K; LERK, CF

    1993-01-01

    The consolidation and compaction properties of granule fractions prepared by dry granulation (slugging) of alpha-lactose monohydrate and roller dried beta-lactose, respectively, were studied. The results showed that the compactibility of the granule fractions was determined by the type of lactose

  4. Neuromuscular partitioning, architectural design, and myosin fiber types of the M. vastus lateralis of the llama (Lama glama).

    Science.gov (United States)

    Graziotti, Guillermo H; Palencia, Pablo; Delhon, Gustavo; Rivero, José-Luis L

    2004-11-01

    The llama (Lama glama) is one of the few mammals of relatively large body size in which three fast myosin heavy chain isoforms (i.e., IIA, IIX, IIB) are extensively expressed in their locomotory muscles. This study was designed to gain insight into the morphological and functional organization of skeletal musculature in this peculiar animal model. The neuromuscular partitioning, architectural design, and myosin fiber types were systematically studied in the M. vastus lateralis of adult llamas (n = 15). Four nonoverlapping neuromuscular partitions or compartments were identified macroscopically (using a modified Sihler's technique for muscle depigmentation), although they did not conform strictly to the definitions of "neuromuscular compartments." Each neuromuscular partition was innervated by primary branches of the femoral nerve and was arranged within the muscle as paired partitions, two in parallel (deep-superficial compartmentalization) and the other two in-series (proximo-distal compartmentalization). These neuromuscular partitions of the muscle varied in their respective architectural designs (studied after partial digestion with diluted nitric acid) and myosin fiber type characteristics (identified immunohistochemically with specific anti-myosin monoclonal antibodies, then examined by quantitative histochemistry and image analysis). The deep partitions of the muscle had longer fibers, with lower angles of pinnation, and higher percentages of fast-glycolytic fibers than the superficial partitions of the muscle. These differences clearly suggest a division of labor in the whole M. vastus lateralis of llamas, with deep partitions exhibiting features well adapted for dynamic activities in the extension of stifle, whereas superficial portions seem to be related to the antigravitational role of the muscle in preserving the extension of the stifle during standing and stance phase of the stride. This peculiar structural and functional organization of the llama M

  5. Optical absorption in compact and extended dendrimers

    International Nuclear Information System (INIS)

    Supritz, C.; Engelmann, A.; Reineker, P.

    2005-01-01

    Dendrimers are highly branched molecules, which are expected to be useful, for example, as efficient artificial light harvesting systems, in nano-technological or in medical applications. There are two different classes of dendrimers: compact dendrimers with constant distance between neighboring branching points throughout the macromolecule and extended dendrimers, where this distance increases from the system periphery to the center. We investigate the linear optical absorption spectra of these dendrimer types using the Frenkel exciton concept. The electron-phonon interaction is taken into account by introducing a heat bath that interacts with the exciton in a stochastic manner. We discuss compact dendrimers with equal excitation energies at all molecules, dendrimers with a functionalized core as well as with a whole branch functionalized. Furthermore the line shape of a compact dendrimer is discussed when neighboring molecules at the periphery interact and when all molecules have randomly distributed excitation energies due to disorder. Finally, we discuss two models for extended dendrimers

  6. Procedural and clinical outcomes after use of the glycoprotein IIb/IIIa inhibitor abciximab for saphenous vein graft interventions

    Energy Technology Data Exchange (ETDEWEB)

    Harskamp, Ralf E., E-mail: r.e.harskamp@gmail.com [Academic Medical Center–University of Amsterdam, Amsterdam (Netherlands); VU University Medical Center, Amsterdam (Netherlands); Duke Clinical Research Institute, Durham, NC (United States); Hoedemaker, Niels [Academic Medical Center–University of Amsterdam, Amsterdam (Netherlands); Newby, L. Kristin [Duke Clinical Research Institute, Durham, NC (United States); Woudstra, Pier; Grundeken, Maik J.; Beijk, Marcel A.; Piek, Jan J.; Tijssen, Jan G. [Academic Medical Center–University of Amsterdam, Amsterdam (Netherlands); Mehta, Rajendra H. [Duke Clinical Research Institute, Durham, NC (United States); Winter, Robbert J. de [Academic Medical Center–University of Amsterdam, Amsterdam (Netherlands)

    2016-01-15

    Background: Percutaneous coronary intervention (PCI) of saphenous vein grafts (SVG) poses a high-risk for distal coronary thromboembolic events. Glycoprotein IIb/IIIa inhibitors are frequently used in hope of reducing the impact of this, although the safety and efficacy of these drugs to improve outcomes in this setting are understudied. Methods: Patients were included if they had prior coronary artery bypass surgery and subsequently underwent PCI of ≥ 1 SVG graft at a Dutch academic center between 1997 and 2008. These patients were matched 1:1 based on peri-procedural use of abciximab using a propensity-score matching algorithm based on 17 variables. Conditional logistic regression and Cox regression stratified on matched pairs were performed to evaluate the association between abciximab use and MACCE (the composite measure of mortality, myocardial infarction, stroke and repeat revascularization) at 30 days and up to 1 year. Results: The composite of 30-day MACCE occurred in 18 patients (15.3%) in the abciximab group and 16 patients (13.6%) in the propensity matched control group (OR: 1.13, 95% CI: 0.57–2.21, p = 0.73). At 1-year follow-up, MACCE rates were also similar (32.5% vs. 33.9%, HR: 0.97, 95% CI: 0.59–1.59). Major bleeding (BARC types 3a–c) was higher in the abciximab group (11.9% vs. 4.2%, OR: 2.80, 95% CI: 1.01–7.77). Ischemic outcomes did not differ among patients with acute coronary syndromes. Conclusion: The use of intravenous abciximab was not associated with improved clinical outcomes up to 1-year among patients undergoing SVG PCI, but was related to more bleeding. - Highlights: • PCI of SVG poses a high-risk for distal coronary thromboembolic events. • Glycoprotein IIb/IIIa inhibitors are frequently used in an attempt to reduce this risk. • We evaluated the safety and efficacy of abciximab (a glycoprotein IIb/IIIa inhibitor) using a propensity-score matched analysis of 236 patients at a large academic medical center. • Thirty

  7. Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice

    Science.gov (United States)

    Tanigaki, Keiji; Chambliss, Ken L.; Yuhanna, Ivan S.; Sacharidou, Anastasia; Ahmed, Mohamed; Atochin, Dmitriy N.; Huang, Paul L.

    2016-01-01

    Modest elevations in C-reactive protein (CRP) are associated with type 2 diabetes. We previously revealed in mice that increased CRP causes insulin resistance and mice globally deficient in the CRP receptor Fcγ receptor IIB (FcγRIIB) were protected from the disorder. FcγRIIB is expressed in numerous cell types including endothelium and B lymphocytes. Here we investigated how endothelial FcγRIIB influences glucose homeostasis, using mice with elevated CRP expressing or lacking endothelial FcγRIIB. Whereas increased CRP caused insulin resistance in mice expressing endothelial FcγRIIB, mice deficient in the endothelial receptor were protected. The insulin resistance with endothelial FcγRIIB activation was due to impaired skeletal muscle glucose uptake caused by attenuated insulin delivery, and it was associated with blunted endothelial nitric oxide synthase (eNOS) activation in skeletal muscle. In culture, CRP suppressed endothelial cell insulin transcytosis via FcγRIIB activation and eNOS antagonism. Furthermore, in knock-in mice harboring constitutively active eNOS, elevated CRP did not invoke insulin resistance. Collectively these findings reveal that by inhibiting eNOS, endothelial FcγRIIB activation by CRP blunts insulin delivery to skeletal muscle to cause insulin resistance. Thus, a series of mechanisms in endothelium that impairs insulin movement has been identified that may contribute to type 2 diabetes pathogenesis. PMID:27207525

  8. Scale invariance of the η-deformed AdS5×S5 superstring, T-duality and modified type II equations

    Directory of Open Access Journals (Sweden)

    G. Arutyunov

    2016-02-01

    Full Text Available We consider the ABF background underlying the η-deformed AdS5×S5 sigma model. This background fails to satisfy the standard IIB supergravity equations which indicates that the corresponding sigma model is not Weyl invariant, i.e. does not define a critical string theory in the usual sense. We argue that the ABF background should still define a UV finite theory on a flat 2d world-sheet implying that the η-deformed model is scale invariant. This property follows from the formal relation via T-duality between the η-deformed model and the one defined by an exact type IIB supergravity solution that has 6 isometries albeit broken by a linear dilaton. We find that the ABF background satisfies candidate type IIB scale invariance conditions which for the R–R field strengths are of the second order in derivatives. Surprisingly, we also find that the ABF background obeys an interesting modification of the standard IIB supergravity equations that are first order in derivatives of R–R fields. These modified equations explicitly depend on Killing vectors of the ABF background and, although not universal, they imply the universal scale invariance conditions. Moreover, we show that it is precisely the non-isometric dilaton of the T-dual solution that leads, after T-duality, to modification of type II equations from their standard form. We conjecture that the modified equations should follow from κ-symmetry of the η-deformed model. All our observations apply also to η-deformations of AdS3×S3×T4and AdS2×S2×T6models.

  9. Skeletal muscle myostatin mRNA expression is fiber-type specific and increases during hindlimb unloading

    Science.gov (United States)

    Carlson, C. J.; Booth, F. W.; Gordon, S. E.

    1999-01-01

    Transgenic mice lacking a functional myostatin (MSTN) gene demonstrate greater skeletal muscle mass resulting from muscle fiber hypertrophy and hyperplasia (McPherron, A. C., A. M. Lawler, and S. -J. Lee. Nature 387: 83-90, 1997). Therefore, we hypothesized that, in normal mice, MSTN may act as a negative regulator of muscle mass. Specifically, we hypothesized that the predominately slow (type I) soleus muscle, which demonstrates greater atrophy than the fast (type II) gastrocnemius-plantaris complex (Gast/PLT), would show more elevation in MSTN mRNA abundance during hindlimb unloading (HU). Surprisingly, MSTN mRNA was not detectable in weight-bearing or HU soleus muscle, which atrophied 42% by the 7th day of HU in female ICR mice. In contrast, MSTN mRNA was present in weight-bearing Gast/PLT muscle and was significantly elevated (67%) at 1 day but not at 3 or 7 days of HU. However, the Gast/PLT muscle had only atrophied 17% by the 7th day of HU. Because the soleus is composed only of type I and IIa fibers, whereas the Gast/PLT expresses type IId/x and IIb in addition to type I and IIa, it was necessary to perform a more careful analysis of the relationship between MSTN mRNA levels and myosin heavy-chain (MHC) isoform expression (as a marker of fiber type). A significant correlation (r = 0.725, P < 0. 0005) was noted between the percentage of MHC isoform IIb expression and MSTN mRNA abundance in several muscles of the mouse hindlimb. These results indicate that MSTN expression is not strongly associated with muscle atrophy induced by HU; however, it is strongly associated with MHC isoform IIb expression in normal muscle.

  10. Possibility of higher-dimensional anisotropic compact star

    International Nuclear Information System (INIS)

    Bhar, Piyali; Rahaman, Farook; Ray, Saibal; Chatterjee, Vikram

    2015-01-01

    We provide a new class of interior solutions for anisotropic stars admitting conformal motion in higher-dimensional noncommutative spacetime. The Einstein field equations are solved by choosing a particular density distribution function of Lorentzian type as provided by Nazari and Mehdipour [1, 2] under a noncommutative geometry. Several cases with 4 and higher dimensions, e.g. 5, 6, and 11 dimensions, are discussed separately. An overall observation is that the model parameters, such as density, radial pressure, transverse pressure, and anisotropy, all are well behaved and represent a compact star with mass 2.27 M s un and radius 4.17 km. However, emphasis is put on the acceptability of the model from a physical point of view. As a consequence it is observed that higher dimensions, i.e. beyond 4D spacetime, exhibit several interesting yet bizarre features, which are not at all untenable for a compact stellar model of strange quark type; thus this dictates the possibility of its extra-dimensional existence. (orig.)

  11. Possibility of higher-dimensional anisotropic compact star

    Energy Technology Data Exchange (ETDEWEB)

    Bhar, Piyali; Rahaman, Farook [Jadavpur University, Department of Mathematics, Kolkata, West Bengal (India); Ray, Saibal [Government College of Engineering and Ceramic Technology, Department of Physics, Kolkata, West Bengal (India); Chatterjee, Vikram [Central Footwear Training Centre, Department of Physics, Parganas, West Bengal (India)

    2015-05-15

    We provide a new class of interior solutions for anisotropic stars admitting conformal motion in higher-dimensional noncommutative spacetime. The Einstein field equations are solved by choosing a particular density distribution function of Lorentzian type as provided by Nazari and Mehdipour [1, 2] under a noncommutative geometry. Several cases with 4 and higher dimensions, e.g. 5, 6, and 11 dimensions, are discussed separately. An overall observation is that the model parameters, such as density, radial pressure, transverse pressure, and anisotropy, all are well behaved and represent a compact star with mass 2.27 M{sub s}un and radius 4.17 km. However, emphasis is put on the acceptability of the model from a physical point of view. As a consequence it is observed that higher dimensions, i.e. beyond 4D spacetime, exhibit several interesting yet bizarre features, which are not at all untenable for a compact stellar model of strange quark type; thus this dictates the possibility of its extra-dimensional existence. (orig.)

  12. Global embeddings for branes at toric singularities

    CERN Document Server

    Balasubramanian, Vijay; Braun, Volker; García-Etxebarria, Iñaki

    2012-01-01

    We describe how local toric singularities, including the Toric Lego construction, can be embedded in compact Calabi-Yau manifolds. We study in detail the addition of D-branes, including non-compact flavor branes as typically used in semi-realistic model building. The global geometry provides constraints on allowable local models. As an illustration of our discussion we focus on D3 and D7-branes on (the partially resolved) (dP0)^3 singularity, its embedding in a specific Calabi-Yau manifold as a hypersurface in a toric variety, the related type IIB orientifold compactification, as well as the corresponding F-theory uplift. Our techniques generalize naturally to complete intersections, and to a large class of F-theory backgrounds with singularities.

  13. Diffusion through statically compacted clay

    International Nuclear Information System (INIS)

    Ho, C.L.; Shebl, M.A.A.

    1994-01-01

    This paper presents experimental work on the effect of compaction on contaminant flow through clay liners. The experimental program included evaluation of soil properties, compaction, permeability and solute diffusion. A permeameter was built of non reactive materials to test samples compacted at different water contents and compactive efforts. The flow of a permeating solute, LiCl, was monitored. Effluent samples were collected for solute concentration measurements. The concentrations were measured by performing atomic adsorption tests. The analyzed results showed different diffusion characteristics when compaction conditions changed. At each compactive effort, permeability decreased as molding water content increased. Consequently, transit time (measured at relative concentration 50%) increased and diffusivity decreased. As compactive effort increased for soils compacted dry of optimum, permeability and diffusion decreased. On the other hand, as compactive effort increased for soils compacted wet of optimum, permeability and diffusivity increased. Tortuosity factor was indirectly measured from the diffusion and retardation rate. Tortuosity factor also decreased as placement water content was increased from dry of optimum to wet of optimum. Then decreases were more pronounced for low compactive effort tests. 27 refs., 7 figs., 5 tabs

  14. IIA/B, Wound and Wrapped

    International Nuclear Information System (INIS)

    Danielsson, Ulf H.; Guijosa, Alberto; Kruczenski, Martin

    2000-01-01

    We examine the T-duality relation between 1+1 NCOS and the DLCQ limit of type IIA string theory. We show that, as long as there is a compact dimension, one can meaningfully define an 'NCOS' limit of IIB/A string theory even in the absence of D-branes (and even if there is no B-field). This yields a theory of closed strings with strictly positive winding, which is T-dual to DLCQ IIA/B without any D-branes. We call this the Type IIB/A Wound String Theory. The existence of decoupled sectors can be seen directly from the energy spectrum, and mirrors that of the DLCQ theory. It becomes clear then that all of the different p+1 NCOS theories are simply different states of this single Wound IIA/B theory which contain D-branes. We study some of the properties of this theory. In particular, we show that upon toroidal compactification, Wound string theory is U-dual to various Wrapped Brane theories which contain OM theory and the ODp theories as special states. (author)

  15. Increased risk for vascular complications due to GP IIb/IIIa-antagonists in patients with cardiogenic shock supported by intraaortic balloon pump (IABP

    Directory of Open Access Journals (Sweden)

    Jens Röther

    2015-08-01

    Conclusion: Vascular events with the use of IABP are common but in our study, not significantly associated with a higher mortality. Treatment with GP IIb/IIIa-antagonists is associated with a higher risk of vascular events.

  16. ARE ALL SHORT-HARD GAMMA-RAY BURSTS PRODUCED FROM MERGERS OF COMPACT STELLAR OBJECTS?

    International Nuclear Information System (INIS)

    Virgili, Francisco J.; Zhang Bing; O'Brien, Paul; Troja, Eleonora

    2011-01-01

    The origin and progenitors of short-hard gamma-ray bursts (GRBs) remain a puzzle and a highly debated topic. Recent Swift observations suggest that these GRBs may be related to catastrophic explosions in degenerate compact stars, denoted as 'Type I' GRBs. The most popular models include the merger of two compact stellar objects (NS-NS or NS-BH). We utilize a Monte Carlo approach to determine whether a merger progenitor model can self-consistently account for all the observations of short-hard GRBs, including a sample with redshift measurements in the Swift era (z-known sample) and the CGRO/BATSE sample. We apply various merger time delay distributions invoked in compact star merger models to derive the redshift distributions of these Type I GRBs, and then constrain the unknown luminosity function of Type I GRBs using the observed luminosity-redshift (L-z) distributions of the z-known sample. The best luminosity function model, together with the adopted merger delay model, is then applied to confront the peak flux distribution (log N-log P distribution) of the BATSE and Swift samples. We find that for all the merger models invoking a range of merger delay timescales (including those invoking a large fraction of 'prompt mergers'), it is difficult to reconcile the models with all the data. The data are instead statistically consistent with the following two possible scenarios. First, that short/hard GRBs are a superposition of compact-star-merger-origin (Type I) GRBs and a population of GRBs that track the star formation history, which are probably related to the deaths of massive stars (Type II GRBs). Second, the entire short/hard GRB population is consistent with a typical delay of 2 Gyr with respect to the star formation history with modest scatter. This may point toward a different Type I progenitor than the traditional compact star merger models.

  17. Evaluation of the Strength Variation of Normal and Lightweight Self-Compacting Concrete in Full Scale Walls

    DEFF Research Database (Denmark)

    Hosseinali, M.; Ranjbar, M. M.; Rezvani, S. M.

    2011-01-01

    -destructive testing. Self-compacting concrete (SCC) and lightweight self-compacting concrete (LWSCC) with different admixtures were tested and compared with normal concrete (NC). The results were also compared with results for standard cubic samples. The results demonstrate the effect of concrete type on the in situ......The strength of cast concrete along the height and length of large structural members might vary due to inadequate compaction, segregation, bleeding, head pressure, and material type. The distribution of strength within a series of full scale reinforced concrete walls was examined using non...

  18. Compaction of Ti–6Al–4V powder using high velocity compaction technique

    International Nuclear Information System (INIS)

    Khan, Dil Faraz; Yin, Haiqing; Li, He; Qu, Xuanhui; Khan, Matiullah; Ali, Shujaat; Iqbal, M. Zubair

    2013-01-01

    Highlights: • We compacted Ti–6Al–4V powder by HVC technique. • As impact force rises up, the green density of the compacts increases gradually. • At impact force 1.857 kN relative sintered density of the compacts reaches 99.88%. • Spring back of the green compact’s decreases gradually with increasing impact force. • Mechanical properties of the samples increases with increasing impact force. - Abstract: High velocity compaction technique was applied to the compaction of pre-alloyed, hydride–dehydride Ti–6Al–4V powder. The powder was pressed in single stroke with a compaction speed of 7.10–8.70 ms −1 . When the speed was 8.70 ms −1 , the relative density of the compacts reaches up to 85.89% with a green density of 3.831 g cm −3 . The green samples were sintered at 1300 °C in Ar-gas atmosphere. Scanning electron microscope (SEM) was used to examine the surface of the sintered samples. Density and mechanical properties such as Vickers micro hardness and bending strength of the powder samples were investigated. Experimental results indicated that with the increase in impact force, the density and mechanical properties of the compacts increased. The sintered compacts exhibited a maximum relative density of 99.88% with a sintered density of 4.415 g cm −3 , hardness of 364–483 HV and the bending strength in the range of 103–126.78 MPa. The springback of the compacts decreased with increasing impact force

  19. H I absorption in nearby compact radio galaxies

    Science.gov (United States)

    Glowacki, M.; Allison, J. R.; Sadler, E. M.; Moss, V. A.; Curran, S. J.; Musaeva, A.; Deng, C.; Parry, R.; Sligo, M. C.

    2017-05-01

    H I absorption studies yield information on both active galactic nucleus (AGN) feeding and feedback processes. This AGN activity interacts with the neutral gas in compact radio sources, which are believed to represent the young or recently re-triggered AGN population. We present the results of a survey for H I absorption in a sample of 66 compact radio sources at 0.040 100 km s-1) features, indicative of disturbed gas kinematics. Such broad, shallow and offset features are also found within low-excitation radio galaxies which is attributed to disturbed circumnuclear gas, consistent with early-type galaxies typically devoid of a gas-rich disc. Comparing mid-infrared colours of our galaxies with H I detections indicates that narrow and deep absorption features are preferentially found in late-type and high-excitation radio galaxies in our sample. These features are attributed to gas in galactic discs. By combining XMM-Newton archival data with 21-cm data, we find support that absorbed X-ray sources may be good tracers of H I content within the host galaxy. This sample extends previous H I surveys in compact radio galaxies to lower radio luminosities and provides a basis for future work exploring the higher redshift universe.

  20. Effect of target-fixture geometry on shock-wave compacted copper powders

    Science.gov (United States)

    Kim, Wooyeol; Ahn, Dong-Hyun; Yoon, Jae Ik; Park, Lee Ju; Kim, Hyoung Seop

    2018-01-01

    In shock compaction with a single gas gun system, a target fixture is used to safely recover a powder compact processed by shock-wave dynamic impact. However, no standard fixture geometry exists, and its effect on the processed compact is not well studied. In this study, two types of fixture are used for the dynamic compaction of hydrogen-reduced copper powders, and the mechanical properties and microstructures are investigated using the Vickers microhardness test and electron backscatter diffraction, respectively. With the assistance of finite element method simulations, we analyze several shock parameters that are experimentally hard to control. The results of the simulations indicate that the target geometry clearly affects the characteristics of incident and reflected shock waves. The hardness distribution and the microstructure of the compacts also show their dependence on the geometry. With the results of the simulations and the experiment, it is concluded that the target geometry affects the shock wave propagation and wave interaction in the specimen.

  1. Sobolev Spaces on Locally Compact Abelian Groups: Compact Embeddings and Local Spaces

    Directory of Open Access Journals (Sweden)

    Przemysław Górka

    2014-01-01

    Full Text Available We continue our research on Sobolev spaces on locally compact abelian (LCA groups motivated by our work on equations with infinitely many derivatives of interest for string theory and cosmology. In this paper, we focus on compact embedding results and we prove an analog for LCA groups of the classical Rellich lemma and of the Rellich-Kondrachov compactness theorem. Furthermore, we introduce Sobolev spaces on subsets of LCA groups and study its main properties, including the existence of compact embeddings into Lp-spaces.

  2. Roller compaction: Effect of relative humidity of lactose powder.

    Science.gov (United States)

    Omar, Chalak S; Dhenge, Ranjit M; Palzer, Stefan; Hounslow, Michael J; Salman, Agba D

    2016-09-01

    The effect of storage at different relative humidity conditions, for various types of lactose, on roller compaction behaviour was investigated. Three types of lactose were used in this study: anhydrous lactose (SuperTab21AN), spray dried lactose (SuperTab11SD) and α-lactose monohydrate 200M. These powders differ in their amorphous contents, due to different manufacturing processes. The powders were stored in a climatic chamber at different relative humidity values ranging from 10% to 80% RH. It was found that the roller compaction behaviour and ribbon properties were different for powders conditioned to different relative humidities. The amount of fines produced, which is undesirable in roller compaction, was found to be different at different relative humidity. The minimum amount of fines produced was found to be for powders conditioned at 20-40% RH. The maximum amount of fines was produced for powders conditioned at 80% RH. This was attributed to the decrease in powder flowability, as indicated by the flow function coefficient ffc and the angle of repose. Particle Image Velocimetry (PIV) was also applied to determine the velocity of primary particles during ribbon production, and it was found that the velocity of the powder during the roller compaction decreased with powders stored at high RH. This resulted in less powder being present in the compaction zone at the edges of the rollers, which resulted in ribbons with a smaller overall width. The relative humidity for the storage of powders has shown to have minimal effect on the ribbon tensile strength at low RH conditions (10-20%). The lowest tensile strength of ribbons produced from lactose 200M and SD was for powders conditioned at 80% RH, whereas, ribbons produced from lactose 21AN at the same condition of 80% RH showed the highest tensile strength. The storage RH range 20-40% was found to be an optimum condition for roll compacting three lactose powders, as it resulted in a minimum amount of fines in the

  3. An Experiment on the Carbonization of Fuel Compact Matrix Graphite for HTGR

    International Nuclear Information System (INIS)

    Lee, Young Woo; Kim, Joo Hyoung; Cho, Moon Sung

    2012-01-01

    The fuel element for HTGR is manufactured by mixing coated fuel particles with matrix graphite powder and forming into either pebble type or cylindrical type compacts depending on their use in different HTGR cores. The coated fuel particle, the so-called TRISO particle, consists of 500-μm spherical UO 2 particles coated with the low density buffer Pyrolytic Carbon (PyC) layer, the inner and outer high density PyC layer and SiC layer sandwiched between the two inner and outer PyC layers. The coated TRISO particles are mixed with a properly prepared matrix graphite powder, pressed into a spherical shape or a cylindrical compact, and finally heat-treated at about 1800 .deg. C. These fuel elements can have different sizes and forms of compact. The basic steps for manufacturing a fuel element include preparation of graphite matrix powder, over coating the fuel particles, mixing the fuel particles with a matrix powder, carbonizing green compact, and the final high-temperature heat treatment of the carbonized fuel compact. The carbonization is a process step where the binder that is incorporated during the matrix graphite powder preparation step is evaporated and the residue of the binder is carbonized during the heat treatment at about 1073 K, In order to develop a fuel compact fabrication technology, and for fuel matrix graphite to meet the required material properties, it is of extreme importance to investigate the relationship among the process parameters of the matrix graphite powder preparation, fabrication parameters of fuel element green compact and the carbonization condition, which has a strong influence on further steps and the material properties of fuel element. In this work, the carbonization behavior of green compact samples prepared from the matrix graphite powder mixtures with different binder materials was investigated in order to elucidate the behavior of binders during the carbonization heat treatment by analyzing the change in weight, density and its

  4. Survival of nonsurgically staged patients with negative lymphangiograms who had Stage IIB carcinoma of the cervix treated by pelvic radiation plus hydroxyurea

    International Nuclear Information System (INIS)

    Piver, M.S.; Krishnamsetty, R.M.; Emrich, L.J.

    1985-01-01

    Twenty patients with Stage IIB carcinoma of the cervix who did not undergo pretherapy para-aortic lymphadenectomy, but who had negative preradiation therapy lymphangiograms, were treated with pelvic radiation plus hydroxyurea. Patients received a median of 5020 rads of pelvic radiation plus 4000 rads of radium to point A. During radiation therapy and for a total of 12 weeks, patients received hydroxyurea administered at a dose of 80 mg/kg of body weight every 3 days if the white blood cell count was greater than or equal to 2,500/mm3 and platelets were greater than or equal to 75,000/mm3. The median follow-up time was 28 months (6 to 83 months). The estimated 5-year survival rate was 92%. Seventeen patients are alive with no evidence of disease (median, 28 months); one died of intercurrent disease with no evidence of disease (17 months); one is alive with no evidence of disease after recurrence (18 months); and one died of cervical cancer (22 months). The survival rate of patients with nonsurgically staged negative pretherapy lymphangiograms who had Stage IIB cervical cancer treated by pelvic radiation therapy plus hydroxyurea approximated the improved survival rate reported for patients with negative pretherapy para-aortic lymphadenectomy who were treated with pelvic radiation therapy plus hydroxyurea. Both studies would suggest that pelvic radiation plus hydroxyurea improves the rate of survival in patients with Stage IIB cervical cancer

  5. On the construction of SL(2,Z) type IIB 5-branes

    International Nuclear Information System (INIS)

    Lu, J.X.; Roy, S.

    1999-01-01

    This talk reviews our recent work on the construction of SL(2,Z) multiplets of type lIB superfivebranes. We here pay particular attention to the methods employed and some salient features of the solutions. (author)

  6. Genomic clone encoding the α chain of the OKM1, LFA-1, and platelet glycoprotein IIb-IIIa molecules

    International Nuclear Information System (INIS)

    Cosgrove, L.J.; Sandrin, M.S.; Rajasekariah, P.; McKenzie, I.F.C.

    1986-01-01

    LFA-1, an antigen involved in cytolytic T lymphocyte-mediated killing, and Mac-1, the receptor for complement component C3bi, constitute a family of structurally and functionally related cell surface glycoproteins involved in cellular interactions. In both mouse and man, Mac-1 (OKM1) and LFA-1 share a common 95-kDa β subunit but are distinguished by their α chains, which have different cellular distributions, apparent molecular masses (165 and 177 kDa, respectively), and peptide maps. The authors report the isolation of a genomic clone from a human genomic library that on transfection into mouse fibroblasts produced a molecule(s) reactive with monoclonal antibodies to OKM1, to LFA-1, and to platelet glycoprotein IIb-IIIa. This gene was cloned by several cycles of transfection of L cells with a human genomic library cloned in λ phase Charon 4A and subsequent rescue of the λ phage. Transfection with the purified recombinant λ DNA yielded a transfectant that expressed the three human α chains of OKM1, LFA-1, and glycoprotein IIb-IIIa, presumably in association with the murine β chain

  7. Uniaxial backfill block compaction

    International Nuclear Information System (INIS)

    Koskinen, V.

    2012-05-01

    The main parts of the project were: to make a literature survey of the previous uniaxial compaction experiments; do uniaxial compaction tests in laboratory scale; and do industrial scale production tests. Object of the project was to sort out the different factors affecting the quality assurance chain of the backfill block uniaxial production and solve a material sticking to mould problem which appeared during manufacturing the blocks of bentonite and cruched rock mixture. The effect of mineralogical and chemical composition on the long term functionality of the backfill was excluded from the project. However, the used smectite-rich clays have been tested for mineralogical consistency. These tests were done in B and Tech OY according their SOPs. The objective of the Laboratory scale tests was to find right material- and compaction parameters for the industrial scale tests. Direct comparison between the laboratory scale tests and industrial scale tests is not possible because the mould geometry and compaction speed has a big influence for the compaction process. For this reason the selected material parameters were also affected by the previous compaction experiments. The industrial scale tests were done in summer of 2010 in southern Sweden. Blocks were done with uniaxial compaction. A 40 tons of the mixture of bentonite and crushed rock blocks and almost 50 tons of Friedland-clay blocks were compacted. (orig.)

  8. Design of transmission-type phase holograms for a compact radar-cross-section measurement range at 650 GHz.

    Science.gov (United States)

    Noponen, Eero; Tamminen, Aleksi; Vaaja, Matti

    2007-07-10

    A design formalism is presented for transmission-type phase holograms for use in a submillimeter-wave compact radar-cross-section (RCS) measurement range. The design method is based on rigorous electromagnetic grating theory combined with conventional hologram synthesis. Hologram structures consisting of a curved groove pattern on a 320 mmx280 mm Teflon plate are designed to transform an incoming spherical wave at 650 GHz into an output wave generating a 100 mm diameter planar field region (quiet zone) at a distance of 1 m. The reconstructed quiet-zone field is evaluated by a numerical simulation method. The uniformity of the quiet-zone field is further improved by reoptimizing the goal field. Measurement results are given for a test hologram fabricated on Teflon.

  9. Characterization of ceramic powder compacts

    International Nuclear Information System (INIS)

    Yanai, K.; Ishimoto, S.; Kubo, T.; Ito, K.; Ishikawa, T.; Hayashi, H.

    1995-01-01

    UO 2 and Al 2 O 3 powder packing structures in cylindrical powder compacts are observed by scanning electron microscopy using polished cross sections of compacts fixed by low viscosity epoxy resin. Hard aggregates which are not destroyed during powder compaction are observed in some of the UO 2 powder compacts. A technique to measure local density in powder compacts is developed based on counting characteristic X-ray intensity by energy dispersive X-ray analysis (EDX). The local density of the corner portion of the powder compact fabricated by double-acting dry press is higher than that of the inner portion. ((orig.))

  10. HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit's decoding groove.

    Science.gov (United States)

    Filbin, Megan E; Kieft, Jeffrey S

    2011-07-01

    Hepatitis C virus (HCV) uses a structured internal ribosome entry site (IRES) RNA to recruit the translation machinery to the viral RNA and begin protein synthesis without the ribosomal scanning process required for canonical translation initiation. Different IRES structural domains are used in this process, which begins with direct binding of the 40S ribosomal subunit to the IRES RNA and involves specific manipulation of the translational machinery. We have found that upon initial 40S subunit binding, the stem-loop domain of the IRES that contains the start codon unwinds and adopts a stable configuration within the subunit's decoding groove. This configuration depends on the sequence and structure of a different stem-loop domain (domain IIb) located far from the start codon in sequence, but spatially proximal in the IRES•40S complex. Mutation of domain IIb results in misconfiguration of the HCV RNA in the decoding groove that includes changes in the placement of the AUG start codon, and a substantial decrease in the ability of the IRES to initiate translation. Our results show that two distal regions of the IRES are structurally communicating at the initial step of 40S subunit binding and suggest that this is an important step in driving protein synthesis.

  11. População de Metarhizium anisopliae em diferentes tipos e graus de compactação do solo Metarhizium anisopliae population in differents soil types and compactness degrees

    Directory of Open Access Journals (Sweden)

    Lourenço Maurício Lanza

    2004-12-01

    Full Text Available Este trabalho objetivou investigar a influência do tipo e compactação do solo na sobrevivência do fungo Metarhizium anisopliae. A sobrevivência do fungo foi determinada em quatro tipos de solos: Latossolo Vermelho textura argilosa, Latossolo Vermelho textura média, Argissolo Vermelho Amarelo textura arenosa média e Argissolo Vermelho Amarelo textura areno-argilosa, com maior teor de matéria orgânica. Para determinar o efeito da compactação na sobrevivência do fungo usaram-se os três primeiros tipos de solos nas densidades de 1,12, 1,32, 1,50g cm-3; 1,22, 1,44, 1,65g cm-3; 1,30, 1,50, 1,70g cm-3, respectivamente. Por meio da contagem de unidades formadoras de colônias (UFC em placas de Petri, fizeram-se avaliações da sobrevivência do fungo, após zero, 20, 40, 60, 80, 100 e 120 dias de incubação a 27 ± 1ºC. Houve influência significativa do tipo de solo e do grau de compactação na sobrevivência do fungo, obtendo-se maior quantidade de UFC no solo textura areno-argilosa. Entre os demais solos, a maior sobrevivência ocorreu no solo textura arenosa e a menor no solo textura argilosa. O efeito da compactação foi significativo para o tipo de solo, exceto no solo textura arenosa. Independentemente do tipo de solo, a maior sobrevivência foi observada nos valores médios de densidade. A compactação teve maior impacto no solo textura média, onde ocorreu queda mais acentuada na quantidade de UFC em todas as densidades.The aim of this work was to investigate the effect of different soil types and compactness on Metarhizium anisopliae survival. The fungus survivorship was determined in four soil types: Red Latosol with clay texture, Red Latosol with medium texture, Red Yellow Podzolic with medium sand texture and Red Yellow Podzolic with sand-clay texture, with higher amount of organic material. To determine the effect of compactness on fungus survival the first three soil types were used with the following densities

  12. [Complications of surgical stage of treatment in patients with cancer of cervix uteri stage IIB].

    Science.gov (United States)

    Kryzhanivs'ka, A Ie

    2013-11-01

    The results of treatment of 127 patients, suffering cervix uteri cancer stage IIB in period of 1998 - 2012 yrs, were analyzed. Complications of surgical stage of the combined treatment have had occurred in 40.9% patients, including 40.5% patients, to whom neoadjuvant chemotherapy was conducted and in 41.5%--radiation therapy (RTH). The main postoperative complications--retroperitoneal lymphatic cysts--were revealed in 35.4% patients. The factors, raising the risk of postoperative complications occurrence, are following: the primary tumor spreading, metastatic affection of lymphatic nodes of pelvic cavity, preoperative conduction of RTH or chemotherapy.

  13. Compact Infrasonic Windscreen

    Science.gov (United States)

    Zuckerwar, Allan J.; Shams, Qamar A.; Sealey, Bradley S.; Comeaux, Toby

    2005-01-01

    A compact windscreen has been conceived for a microphone of a type used outdoors to detect atmospheric infrasound from a variety of natural and manmade sources. Wind at the microphone site contaminates received infrasonic signals (defined here as sounds having frequencies <20 Hz), because a microphone cannot distinguish between infrasonic pressures (which propagate at the speed of sound) and convective pressure fluctuations generated by wind turbulence. Hence, success in measurement of outdoor infrasound depends on effective screening of the microphone from the wind. The present compact windscreen is based on a principle: that infrasound at sufficiently large wavelength can penetrate any barrier of practical thickness. Thus, a windscreen having solid, non-porous walls can block convected pressure fluctuations from the wind while transmitting infrasonic acoustic waves. The transmission coefficient depends strongly upon the ratio between the acoustic impedance of the windscreen and that of air. Several materials have been found to have impedance ratios that render them suitable for use in constructing walls that have practical thicknesses and are capable of high transmission of infrasound. These materials (with their impedance ratios in parentheses) are polyurethane foam (222), space shuttle tile material (332), balsa (323), cedar (3,151), and pine (4,713).

  14. Compact high voltage, high peak power, high frequency transformer for converter type modulator applications.

    Science.gov (United States)

    Reghu, T; Mandloi, V; Shrivastava, Purushottam

    2016-04-01

    The design and development of a compact high voltage, high peak power, high frequency transformer for a converter type modulator of klystron amplifiers is presented. The transformer has been designed to operate at a frequency of 20 kHz and at a flux swing of ±0.6 T. Iron (Fe) based nanocrystalline material has been selected as a core for the construction of the transformer. The transformer employs a specially designed solid Teflon bobbin having 120 kV insulation for winding the high voltage secondary windings. The flux swing of the core has been experimentally found by plotting the hysteresis loop at actual operating conditions. Based on the design, a prototype transformer has been built which is per se a unique combination of high voltage, high frequency, and peak power specifications. The transformer was able to provide 58 kV (pk-pk) at the secondary with a peak power handling capability of 700 kVA. The transformation ratio was 1:17. The performance of the transformer is also presented and discussed.

  15. Grout compactness monitoring of concrete-filled fiber-reinforced polymer tube using electromechanical impedance

    Science.gov (United States)

    Shi, Yaokun; Luo, Mingzhang; Li, Weijie; Song, Gangbing

    2018-05-01

    The concrete-filled fiber-reinforced polymer tube (CFFT) is a type of structural element widely used in corrosive environments. Poor grout compactness results in incomplete contact or even no contact between the fiber-reinforced polymer (FRP) tube and the concrete grout, which reduces the load bearing capacity of a CFFT. The monitoring of grout compactness for CFFTs is important. The piezoceramic-based electromechanical impedance (EMI) method has emerged as an efficient and low-cost structural health monitoring technique. This paper presents a feasibility study using the EMI method to monitor grout compactness of CFFTs. In this research, CFFT specimens with different levels of compactness (empty, 1/5, 1/3, 1/2, 2/3, and full compactness) were prepared and subjected to EMI measurement by using four piezoceramic patches that were bonded circumferentially along the outer surface of the CFFT. To analyze the correlation between grout compactness and EMI signatures, a compactness index (CI) was proposed based on the root-mean-square deviation (RMSD). The experimental results show that the changes in admittance signatures are able to determine the grout compactness qualitatively. The proposed CI is able to effectively identify the compactness of the CFFT, and provides location information of the incomplete concrete infill.

  16. Some observational aspects of compact galactic X-ray sources

    International Nuclear Information System (INIS)

    Heise, J.

    1982-01-01

    This thesis contains the following observations of compact galactic X-ray sources: i) the X-ray experiments onboard the Astronomical Netherlands Satellite ANS, ii) a rocket-borne ultra soft X-ray experiment and iii) the Objective Grating Spectrometer onboard the EINSTEIN observatory. In Chapter I the various types of compact galactic X-ray sources are reviewed and put into the perspective of earlier and following observations. In Chapter II the author presents some of the observations of high luminosity X-ray sources, made with ANS, including the detection of soft X-rays from the compact X-ray binary Hercules X-1 and the ''return to the high state'' of the black hole candidate Cygnus X-1. Chapter III deals with transient X-ray phenomena. Results on low luminosity galactic X-ray sources are collected in Chapter IV. (Auth.)

  17. Development of compact synchrotron radiation facilities TELL-TERAS, NIJI-I∼IV, at ETL

    International Nuclear Information System (INIS)

    Tomimasu, T.

    1990-01-01

    At the Electrotechnical Laboratory (ETL) four compact storage rings, TERAS, NIJI-I∼III, have been already constructed and a compact storage ring, NIJI-IV, with long straight sections for a free electron laser (FEL) experiment will be completed in 1990. The 0.8-GeV ETL storage ring is called TERAS; Tsukuba Electron Ring for Accelerating and Storage. TERAS has been operated since Oct. 1981 for researches on radiometric standards, dissociative photoionization, photodissociation of sulfur containing molecules, solid state physics, ULSI lithography, generation of polarized SR and gamma-rays and for FEL experiment using an transverse optical klystron (TOK). A 10-T three pole wiggler will be installed in 1991 at the straight section where the TOK is installed. NIJI-I is a 0.27-GeV compact ring. NIJI is a Japanese verb meaning 'rainbow' in English. It has been operated from Feb. 1986 to March 1989 for machine study of beam storage higher than 0.5 A at low energies below 0.15-GeV. NIJI-II is a 0.6-GeV conventional type compact ring. It has been operated in Aug. 1989 and will be used for chemical vapor deposition (CVD) and polarized SR experiments. NIJI-III is a 0.62-GeV superconducting type ring. It will be used for ULSI lithography experiments. Before the superconducting coils are installed, NIJI-III with conventional type magnets has been already constructed and operated in June 1989. NIJI-III with the superconducting ones is now operated in June 1990. NIJI-IV is a 0.5-GeV conventional type compact ring with straight sections longer than 7m where a 6.2-m long TOK is installed to achieve UV FEL experiment. (author)

  18. MECHANICS OF DYNAMIC POWDER COMPACTION PROCESS

    OpenAIRE

    Nurettin YAVUZ

    1996-01-01

    In recent years, interest in dynamic compaction methods of metal powders has increased due to the need to improve compaction properties and to increase production rates of compacts. In this paper, review of dynamic and explosive compaction of metal powders are given. An attempt is made to get a better understanding of the compaction process with the mechanicis of powder compaction.

  19. EVIDENCE FOR A COMPACT WOLF-RAYET PROGENITOR FOR THE TYPE Ic SUPERNOVA PTF 10vgv

    Energy Technology Data Exchange (ETDEWEB)

    Corsi, A. [LIGO laboratory, California Institute of Technology, MS 100-36, Pasadena, CA 91125 (United States); Ofek, E. O.; Gal-Yam, A.; Arcavi, I.; Ben-Ami, S.; Rabinak, I. [Department of Particle Physics and Astrophysics, Weizmann Institute of Science, Rehovot 76100 (Israel); Frail, D. A. [National Radio Astronomy Observatory, P.O. Box 0, Socorro, NM 87801 (United States); Poznanski, D. [School of Physics and Astronomy, Tel-Aviv University, Tel-Aviv 69978 (Israel); Mazzali, P. A. [INAF-Osservatorio Astronomico, vicolo dellOsservatorio, 5, I-35122 Padova (Italy); Kulkarni, S. R.; Kasliwal, M. M.; Horesh, A. [Cahill Center for Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Cenko, S. B.; Filippenko, A. V.; Kleiser, I. K. W.; Silverman, J. M. [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Fox, D. B.; Howell, J. L. [Department of Astronomy and Astrophysics, Pennsylvania State University, University Park, PA 16802 (United States); Nakar, E. [Raymond and Beverly Sackler School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978 (Israel); Sari, R., E-mail: corsi@caltech.edu [Racah Institute for Physics, Hebrew University, Jerusalem 91904 (Israel); and others

    2012-03-15

    We present the discovery of PTF 10vgv, a Type Ic supernova (SN) detected by the Palomar Transient Factory, using the Palomar 48 inch telescope (P48). R-band observations of the PTF 10vgv field with P48 probe the SN emission from its very early phases (about two weeks before R-band maximum) and set limits on its flux in the week prior to the discovery. Our sensitive upper limits and early detections constrain the post-shock-breakout luminosity of this event. Via comparison to numerical (analytical) models, we derive an upper-limit of R {approx}< 4.5 R{sub Sun} (R {approx}< 1 R{sub Sun }) on the radius of the progenitor star, a direct indication in favor of a compact Wolf-Rayet star. Applying a similar analysis to the historical observations of SN 1994I yields R {approx}< 1/4 R{sub Sun} for the progenitor radius of this SN.

  20. Migration behaviour of Pu released from Pu-doped glass in compacted bentonite

    International Nuclear Information System (INIS)

    Ashida, T.; Kohara, Y.; Yui, M.

    1994-01-01

    In order to investigate the coupled behavior of Pu release from the waste glass and transport in bentonite, a migration experiment with compacted sodium-type bentonite saturated with distilled water was carried out at room temperature, in which Pu-doped borosilicate glass was sandwiched. Under these conditions, leaching of Pu from the glass, diffusion and sorption of Pu in the compacted bentonite occur simultaneously. (orig.)

  1. Effect of filler types on physical, mechanical and microstructure of self compacting concrete and Flow-able concrete

    Directory of Open Access Journals (Sweden)

    Hafez E. Elyamany

    2014-06-01

    Full Text Available The objective of this study is to evaluate the effect of various filler types on the fresh and hardened properties of self-compacting concrete (SCC and Flow-able concrete. For this purpose, two groups of fillers were selected. The first group was pozzolanic fillers (silica fume and metakaolin while the second group was non-pozzolanic fillers (limestone powder, granite dust and marble dust. Cement contents of 400 kg/m3 and 500 kg/m3 were considered while the used filler material was 7.5%, 10% and 15%. Slump and slump flow, T50, sieve stability and bleeding tests were performed on fresh concrete. The studied hardened properties included unit weight, voids ratio, porosity, and water absorption and cube compressive strength. In addition, thermo-gravimetric analysis, X-ray diffraction analysis and scanning electronic microscope were performed. The test results showed that filler type and content have significant effect on fresh concrete properties where non-pozzolanic fillers improve segregation and bleeding resistance. Generally, filler type and content have significant effect on unit weight, water absorption and voids ratio. In addition, non-pozzolanic fillers have insignificant negative effect on concrete compressive strength. Finally, there was a good correlation between fresh concrete properties and hardened concrete properties for SCC and Flow-able concrete.

  2. Stent parameters predict major adverse clinical events and the response to platelet glycoprotein IIb/IIIa blockade: findings of the ESPRIT trial.

    Science.gov (United States)

    Tcheng, James E; Lim, Ing Haan; Srinivasan, Shankar; Jozic, Joseph; Gibson, C Michael; O'Shea, J Conor; Puma, Joseph A; Simon, Daniel I

    2009-02-01

    Only limited data describe relationships between stent parameters (length and diameter), adverse events after percutaneous coronary intervention, and effects of platelet glycoprotein IIb/IIIa blockade by stent parameters. In this post hoc analysis of the 1983 patients receiving a stent in the Enhanced Suppression of the Platelet Glycoprotein IIb/IIIa Receptor with Integrilin Therapy randomized percutaneous coronary intervention trial of eptifibatide versus placebo, rates of the major adverse cardiac event (MACE) end point (death, myocardial infarction, urgent target-vessel revascularization, or thrombotic bailout) at 48 hours and 1 year were correlated with stent parameters and then analyzed by randomization to eptifibatide versus placebo. In the placebo group, MACE increased with number of stents implanted, total stent length (by quartiles of or=30 mm), and total stented vessel area (by quartiles of area or=292 mm(2)). By stent parameters, MACE at 48 hours was reduced in the eptifibatide group at stent lengths of 18 to or=30 mm (OR, 0.43; 95% CI, 0.25 to 0.75; P=0.003), stent diameters of >2.5 to <3.5 mm (OR, 0.56; 95% CI, 0.39 to 0.82; P=0.002), and with 2 stents implanted (OR, 0.39; 95% CI, 0.22 to 0.69; P=0.001). In the placebo group, near-linear relationships were observed between both increasing stent length and increasing stented vessel area and MACE at 48 hours and 1 year (all, P<0.001); these gradients were flattened in the eptifibatide group (P=0.005 for stent length). Stent parameters predict MACE after percutaneous coronary intervention. Glycoprotein IIb/IIIa blockade mitigates much of the hazard of increasing procedural complexity.

  3. Compact antennas for wireless communications and terminals theory and design

    CERN Document Server

    Laheurte, Jean-Marc

    2012-01-01

    Compact Antennas for Wireless Communications and Terminals deals with compact microwave antennas and, more specifically, with the planar version of these antennas. Planar antennas are the most appropriate type of antenna in modern communication systems and more generally in all applications requiring miniaturization, integration and conformation such as in mobile phone handsets.The book is suitable for students, engineers and scientists eager to understand the principles of planar and small antennas, their design and fabrication issues, and modern aspects such as UWB antennas, recon

  4. Bitistatin-functionalized fluorescent nanodiamond particles specifically bind to purified human platelet integrin receptor αIIbβ3 and activated platelets.

    Science.gov (United States)

    Marcinkiewicz, Cezary; Gerstenhaber, Jonathan A; Sternberg, Mark; Lelkes, Peter I; Feuerstein, Giora

    2017-01-01

    Thromboembolic events (TEE) underwrite key causes of death in developed countries. While advanced imaging technologies such as computed tomography scans serve to diagnose blood clots during acute cardiovascular events, no such technology is available in routine primary care for TEE risk assessment. Here, we describe an imaging platform technology based on bioengineered fluorescent nanodiamond particles (F-NDPs) functionalized with bitistatin (Bit), a disintegrin that specifically binds to the α IIb β 3 integrin, platelet fibrinogen receptor (PFR) on activated platelets. Covalent linkage of purified Bit to F-NDP was concentration-dependent and saturable, as validated by enzyme-linked immunosorbent assay using specific anti-Bit antibodies. F-NDP-Bit interacted with purified PFR, either in immobilized or soluble form. Lotrafiban, a nonpeptide, α IIb β 3 receptor antagonist, specifically blocked F-NDP-Bit-PFR complex formation. Moreover, F-NDP-Bit specifically binds to activated platelets incorporated into a clot generated by thrombin-activated rat platelet-rich plasma (PRP). Our results suggest that engineered F-NDP-Bit particles could serve as noninvasive, "real-time" optical diagnostics for clots present in blood vessels.

  5. Clastic compaction unit classification based on clay content and integrated compaction recovery using well and seismic data

    Directory of Open Access Journals (Sweden)

    Zhong Hong

    2016-11-01

    Full Text Available Abstract Compaction correction is a key part of paleo-geomorphic recovery methods. Yet, the influence of lithology on the porosity evolution is not usually taken into account. Present methods merely classify the lithologies as sandstone and mudstone to undertake separate porosity-depth compaction modeling. However, using just two lithologies is an oversimplification that cannot represent the compaction history. In such schemes, the precision of the compaction recovery is inadequate. To improve the precision of compaction recovery, a depth compaction model has been proposed that involves both porosity and clay content. A clastic lithological compaction unit classification method, based on clay content, has been designed to identify lithological boundaries and establish sets of compaction units. Also, on the basis of the clastic compaction unit classification, two methods of compaction recovery that integrate well and seismic data are employed to extrapolate well-based compaction information outward along seismic lines and recover the paleo-topography of the clastic strata in the region. The examples presented here show that a better understanding of paleo-geomorphology can be gained by applying the proposed compaction recovery technology.

  6. Development of a compact powdery sample negative ion source

    Energy Technology Data Exchange (ETDEWEB)

    Wada, Motoi [Doshisha Univ., Tanabe, Kyoto (Japan). Faculty of Engineering; Sasao, Mamiko; Kawano, Hiroyuki

    1997-02-01

    A gas-feed-free compact negative ion source can be realized by utilizing the process of electron stimulated desorption from powdery sample. A negative ion source of this type is designed to be attached to a standard 1.33 inch copper-gasket-flange. The ion source is operated stable with LiH powder for more than 10 hours with the mass-separated negative hydrogen ion current of 1 nA. The source causes minute gas emission, and particularly suitable for ion beam applications in which a good vacuum is required. The present status of the compact ion source development is briefly described. (author)

  7. The estimation of parameter compaction values for pavement subgrade stabilized with lime

    Science.gov (United States)

    Lubis, A. S.; Muis, Z. A.; Simbolon, C. A.

    2018-02-01

    The type of soil material, field control, maintenance and availability of funds are several factors that must be considered in compaction of the pavement subgrade. In determining the compaction parameters in laboratory desperately requires considerable materials, time and funds, and reliable laboratory operators. If the result of soil classification values can be used to estimate the compaction parameters of a subgrade material, so it would save time, energy, materials and cost on the execution of this work. This is also a clarification (cross check) of the work that has been done by technicians in the laboratory. The study aims to estimate the compaction parameter values ie. maximum dry unit weight (γdmax) and optimum water content (Wopt) of the soil subgrade that stabilized with lime. The tests that conducted in the laboratory of soil mechanics were to determine the index properties (Fines and Liquid Limit/LL) and Standard Compaction Test. Soil samples that have Plasticity Index (PI) > 10% were made with additional 3% lime for 30 samples. By using the Goswami equation, the compaction parameter values can be estimated by equation γd max # = -0,1686 Log G + 1,8434 and Wopt # = 2,9178 log G + 17,086. From the validation calculation, there was a significant positive correlation between the compaction parameter values laboratory and the compaction parameter values estimated, with a 95% confidence interval as a strong relationship.

  8. Development task of compact reactor

    International Nuclear Information System (INIS)

    Kurushima, Morihiro

    1982-01-01

    In the Ministry of International Trade and Industry, studies proceed on the usage of compact medium and small LWRs. As such, the reactors from 100 to 200 MW may meet varieties of demands in scale and kind in view of the saving of petroleum and the economy of nuclear power. In this case, the technology of light water reactors with already established safety will be suitable for the development of compact reactors. The concept of ''nuclear power community'' using the compact reactors in local society and industrial zones was investigated. The following matters are described: need for the introduction of compact reactors, the survey on the compact reactor systems, and the present status and future problems for compact reactor usage. (J.P.N.)

  9. Formulation and Evaluation of Liquisolid Compacts for Olmesartan Medoxomil

    Directory of Open Access Journals (Sweden)

    Shailesh T. Prajapati

    2013-01-01

    Full Text Available Olmesartan medoxomil is an angiotensin type II receptor blocker, antihypertensive agent, administered orally. It is highly lipophilic (log P 5.5 and a poorly water-soluble drug with absolute bioavailability of 26%. The poor dissolution rate of water-insoluble drugs is still a major problem confronting the pharmaceutical industry. The objective of the present investigation was to develop liquisolid compacts for olmesartan medoxomil to improve the dissolution rate. Liquisolid compacts were prepared using Acrysol El 135 as a solvent, Avicel PH 102, Fujicalin and Neusilin as carrier materials, and Aerosil as coating material in different ratios. The interaction between drug and excipients was characterized by DSC and FT-IR studies, which showed that there is no interaction between drug and excipients. The powder characteristics were evaluated by different flow parameters to comply with pharmacopoeial limits. The dissolution studies for liquisolid compacts and conventional formulations were carried out, and it was found that liquisolid compacts with 80% w/w of Acrysol EL 135 to the drug showed significant higher drug release rates than conventional tablets. Amongst carriers used Fujicalin and Neusilin were found to be more effective carrier materials for liquid adsorption.

  10. Myostatin propeptide mutation of the hypermuscular Compact mice decreases the formation of myostatin and improves insulin sensitivity.

    Science.gov (United States)

    Kocsis, Tamas; Trencsenyi, Gyorgy; Szabo, Kitti; Baan, Julia Aliz; Muller, Geza; Mendler, Luca; Garai, Ildiko; Reinauer, Hans; Deak, Ferenc; Dux, Laszlo; Keller-Pinter, Aniko

    2017-03-01

    The TGFβ family member myostatin (growth/differentiation factor-8) is a negative regulator of skeletal muscle growth. The hypermuscular Compact mice carry the 12-bp Mstn(Cmpt-dl1Abc) deletion in the sequence encoding the propeptide region of the precursor promyostatin, and additional modifier genes of the Compact genetic background contribute to determine the full expression of the phenotype. In this study, by using mice strains carrying mutant or wild-type myostatin alleles with the Compact genetic background and nonmutant myostatin with the wild-type background, we studied separately the effect of the Mstn(Cmpt-dl1Abc) mutation or the Compact genetic background on morphology, metabolism, and signaling. We show that both the Compact myostatin mutation and Compact genetic background account for determination of skeletal muscle size. Despite the increased musculature of Compact s, the absolute size of heart and kidney is not influenced by myostatin mutation; however, the Compact genetic background increases them. Both Compact myostatin and genetic background exhibit systemic metabolic effects. The Compact mutation decreases adiposity and improves whole body glucose uptake, insulin sensitivity, and 18 FDG uptake of skeletal muscle and white adipose tissue, whereas the Compact genetic background has the opposite effect. Importantly, the mutation does not prevent the formation of mature myostatin; however, a decrease in myostatin level was observed, leading to altered activation of Smad2, Smad1/5/8, and Akt, and an increased level of p-AS160, a Rab-GTPase-activating protein responsible for GLUT4 translocation. Based on our analysis, the Compact genetic background strengthens the effect of myostatin mutation on muscle mass, but those can compensate for each other when systemic metabolic effects are compared. Copyright © 2017 the American Physiological Society.

  11. Phase IIA and IIB experiments of JAERI/U.S.DOE collaborative program on fusion blanket neutronics

    International Nuclear Information System (INIS)

    Oyama, Yukio

    1989-12-01

    Phase IIA and IIB experiments on fusion blanket neutronics has been performed on a basis of JAERI/USDOE collaborative program. In the Phase II experimental series, a D-T neutron source and a test blanket were contained by a lithium-carbonate enclosure to adjust the incident neutron spectrum to the test blanket so as to simulate that of a fusion reactor. First two series of the Phase II, IIA and IIB, focused especially on influences of beryllium configurations for neutron multiplying zone to neutronic parameters. Measured parameters were tritium production rate using Li-glass and NE213 scintillators, and Li-metal foil and Lithium-oxide block with liquid scintillation technique; neutron spectrum using NE213 scintillator and proton recoil proportional counter; reaction rate using foil activation technique. These parameters were compared among six different beryllium configurations of the experimental system. Consistency between different techniques for each measured parameter was also tested among different experimental systems and confirmed to be within experimental errors. This report describes, in detail, experimental conditions, assemblies, equipments and neutron source in Part I. The part II compiles all information required for a calculational analysis of this experiment, e.g., dimensions of the target room, target assembly, experimental assembly, their material densities and numerical data of experimental results. This compilation provides benchmark data to test calculation models and computing code systems used for a nuclear design of a fusion reactor. (author)

  12. Compaction dynamics of crunchy granular material

    Directory of Open Access Journals (Sweden)

    Guillard François

    2017-01-01

    Full Text Available Compaction of brittle porous material leads to a wide variety of densification patterns. Static compaction bands occurs naturally in rocks or bones, and have important consequences in industry for the manufacturing of powder tablets or metallic foams for example. Recently, oscillatory compaction bands have been observed in brittle porous media like snow or cereals. We will discuss the great variety of densification patterns arising during the compaction of puffed rice, including erratic compaction at low velocity, one or several travelling compaction bands at medium velocity and homogeneous compaction at larger velocity. The conditions of existence of each pattern are studied thanks to a numerical spring lattice model undergoing breakage and is mapped to the phase diagram of the patterns based on dimensionless characteristic quantities. This also allows to rationalise the evolution of the compaction behaviour during a single test. Finally, the localisation of compaction bands is linked to the strain rate sensitivity of the material.

  13. Compaction dynamics of crunchy granular material

    Science.gov (United States)

    Guillard, François; Golshan, Pouya; Shen, Luming; Valdès, Julio R.; Einav, Itai

    2017-06-01

    Compaction of brittle porous material leads to a wide variety of densification patterns. Static compaction bands occurs naturally in rocks or bones, and have important consequences in industry for the manufacturing of powder tablets or metallic foams for example. Recently, oscillatory compaction bands have been observed in brittle porous media like snow or cereals. We will discuss the great variety of densification patterns arising during the compaction of puffed rice, including erratic compaction at low velocity, one or several travelling compaction bands at medium velocity and homogeneous compaction at larger velocity. The conditions of existence of each pattern are studied thanks to a numerical spring lattice model undergoing breakage and is mapped to the phase diagram of the patterns based on dimensionless characteristic quantities. This also allows to rationalise the evolution of the compaction behaviour during a single test. Finally, the localisation of compaction bands is linked to the strain rate sensitivity of the material.

  14. Compact multichannel MEMS based spectrometer for FBG sensing

    DEFF Research Database (Denmark)

    Ganziy, Denis; Rose, Bjarke; Bang, Ole

    2017-01-01

    We propose a novel type of compact multichannel MEMS based spectrometer, where we replace the linear detector with a Digital Micromirror Device (DMD). The DMD is typically cheaper and has better pixel sampling than an InGaAs detector used in the 1550 nm range, which leads to cost reduction...

  15. Advanced Construction of Compact Containment BWR

    International Nuclear Information System (INIS)

    Takahashi, M.; Maruyama, T.; Mori, H.; Hoshino, K.; Hijioka, Y.; Heki, H.; Nakamaru, M.; Hoshi, T.

    2006-01-01

    The reactor concept considered in this paper has a mid/small power output, a compact containment and a simplified BWR configuration with comprehensive safety features. Compact Containment BWR (CCR) is being developed with matured BWR technologies together with innovative systems/components, will provide attractiveness for the energy market in the world due to its flexibility in energy demands as well as in site conditions, its high potential in reducing investment risk and its safety feature facilitating public acceptance. The flexibility is achieved by CCR's mid/small power output of 400 MWe class and capability of long operating cycle (refueling intervals). The high investment potential is expected from CCR's simplification/innovation in design such as natural circulation core cooling with the bottom located short core, top mounted upper entry control rod drives (CRDs) with ring-type dryers and simplified safety system with high pressure resistible primary containment vessel (PCV) concept. The natural circulation core eliminates recirculation pumps as well as needs for maintenance of such pumps. The top mounted upper entry CRDs enable the bottom located short core in RPV. The safety feature mainly consists of large water inventory above the core without large penetration below the top of the core, passive cooling system by isolation condenser (IC), high pressure resistible PCV and in-vessel retention (IVR) capability. The large inventory increases the system response time in case of design base accidents including loss of coolant accidents. The IC suppresses PCV pressure by steam condensation without any AC power. Cooling the molten core inside the RPV if the core should be damaged by loss of core coolability could attain the IVR. CCR's specific self-standing steel high pressure resistible PCV is designed to contain minimum piping and valves inside with reactor pressure vessel (RPV), only 13 m in diameter and 24 m in height. This compact PCV makes it possible to

  16. Summary of Self-compacting Concrete Workability

    OpenAIRE

    GUO Gui-xiang; Duan Hong-jun

    2015-01-01

    On the basis of a large number of domestic and foreign literature, situation and development of self-compacting concrete is introduced. Summary of the compacting theory of self-compacting concrete. And some of the factors affecting the workability of self-compacting concrete were discussed and summarized to a certain extent. Aims to further promote the application and research of self-compacting concrete

  17. Model Compaction Equation

    African Journals Online (AJOL)

    The currently proposed model compaction equation was derived from data sourced from the. Niger Delta and it relates porosity to depth for sandstones under hydrostatic pressure condition. The equation is useful in predicting porosity and compaction trend in hydrostatic sands of the. Niger Delta. GEOLOGICAL SETTING OF ...

  18. Risk model in stage IB1-IIB cervical cancer with positive node after radical hysterectomy

    Directory of Open Access Journals (Sweden)

    Chen Z

    2016-05-01

    Full Text Available Zhilan Chen,1,2,* Kecheng Huang,1,* Zhiyong Lu,1,3 Song Deng,1,4 Jiaqiang Xiong,1 Jia Huang,1 Xiong Li,5 Fangxu Tang,1 Zhihao Wang,6 Haiying Sun,1 Lin Wang,1 Shasha Zhou,1 Xiaoli Wang,1 Yao Jia,1 Ting Hu,1 Juan Gui,7 Dongyi Wan,1 Ding Ma,1 Shuang Li,1 Shixuan Wang11Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Techonology, Wuhan, 2Department of Obstetrics and Gynecology, Wuhan General Hospital of Guangzhou Military Command, Wuhan, 3Hubei Key Laboratory of Embryonic Stem Cell Research, Tai-He Hospital, Hubei University of Medicine, Shiyan, Hubei, 4Department of Obstetrics and Gynecology, University Hospital of Hubei University for Nationalities, Enshi, Hubei, 5Department of Obstetrics and Gynecology, Wuhan Central Hospital, Wuhan, 6Department of Pathology and Pathophysiology, Key Laboratory of Ministry of Education of China for Neurological Disorders, Huazhong University of Science and Techonology, Wuhan, 7Department of Obstetrics and Gynecology, Renmin Hospital, Wuhan University, Wuhan, People’s Republic of China*These authors contributed equally to this workAbstract: The purpose of this study was to identify risk factors in patients with surgically treated node-positive IB1-IIB cervical cancer and to establish a risk model for disease-free survival (DFS and overall survival (OS. A total of 170 patients who underwent radical hysterectomy and bilateral pelvic lymphadenectomy as primary treatment for node-positive International Federation of Gynaecology and Obstetrics (FIGO stage IB1-IIB cervical cancer from January 2002 to December 2008 were retrospectively analyzed. Five published risk models were evaluated in this population. The variables, including common iliac lymph node metastasis and parametrial invasion, were independent predictors of outcome in a multivariate analysis using a Cox regression model. Three distinct prognostic groups (low, intermediate, and high risk

  19. Vibrated and self-compacting fibre reinforced concrete: experimental investigation on the fibre orientation

    Science.gov (United States)

    Conforti, A.; Plizzari, G. A.; Zerbino, R.

    2017-09-01

    In addition to the fibre type and content, the residual properties of fibre reinforced concrete are influenced by fibre orientation. Consequently, the performance fibre reinforced concrete can be affected by its fresh properties (workability, flowing capacity) and by casting and compaction processes adopted. This paper focuses on the study of the orientation of steel or macro-synthetic fibres in two materials characterized by very different fresh properties: vibrated and self-compacting concrete. Four rectangular slabs 1800 mm long, 925 mm wide and 100 mm high were produced changing concrete and fibre type. From each slab, eighteen small prisms (550 mm long) were firstly cut either orthogonal or parallel to casting direction and, secondly, notched and tested in bending according to EN 14651. Experimental results showed that the toughness properties of a thin slab significantly varies both in vibrated and self-compacting concrete, even if in case of self-compacting concrete this variation resulted higher. Steel fibres led to greater variability of results compared to polymer one, underlining a different fibre orientation. A discussion on the relative residual capacity measured on the prisms sawn from the slabs and the parameters obtained from standard specimens is performed.

  20. Is glycoprotein IIb/IIIa antagonism as effective in women as in men following percutaneous coronary intervention?. Lessons from the ESPRIT study.

    Science.gov (United States)

    Fernandes, Laura S; Tcheng, James E; O'Shea, J Conor; Weiner, Bonnie; Lorenz, Todd J; Pacchiana, Cindy; Berdan, Lisa G; Maresh, Kelly J; Joseph, Diane; Madan, Mina; Mann, Tift; Kilaru, Rakhi; Hochman, Judith S; Kleiman, Neal S

    2002-09-18

    The study was done to determine whether eptifibatide, a platelet glycoprotein (GP) IIb/IIIa antagonist, prevents ischemic complications following percutaneous coronary interventions (PCIs) in women as well as in men. Eptifibatide reduces ischemic complications after nonurgent coronary stent interventions. We compared outcomes in women (n = 562) and men (n = 1,502) enrolled in the Enhanced Suppression of the Platelet GP IIb/IIIa Receptor with Integrilin Therapy (ESPRIT) trial of double-bolus eptifibatide during PCI. Women in the ESPRIT trial were older, and more frequently had hypertension, diabetes mellitus, or acute coronary syndromes, but were less likely to have prior PCI or coronary artery bypass graft surgery. The primary end point, a composite at 48 h of death, myocardial infarction (MI), urgent target vessel revascularization (TVR), and unplanned GP IIb/IIIa use, occurred in 10.5% of women and 7.9% of men (p = 0.082). The composite of death, MI, or TVR after one year occurred in 24.5% of women compared with 18% of men (p = 0.0008). At 48 h, eptifibatide reduced the composite of death, MI, and TVR from 14.5% to 6.0% in women versus 9.0% to 6.8% in men. At one year, these differences persisted: 28.9% versus 20.0% for women and 19.5% versus 16.6% for men. No statistical interaction existed between treatment and gender at either 48 h (p = 0.063) or one year (p = 0.2). Bleeding occurred more commonly in women (5.5% vs. 2.6%, p = 0.002), and was more common in eptifibatide-treated women. After adjustment for age, weight, and hypertension, no interaction between treatment and gender was present. Eptifibatide is effective to prevent ischemic complications of PCI in women and may eliminate gender-related differences in PCI outcomes.

  1. Pharmaceutical powder compaction technology

    National Research Council Canada - National Science Library

    Çelik, Metin

    2011-01-01

    ... through the compaction formulation process and application. Compaction of powder constituents both active ingredient and excipients is examined to ensure consistent and reproducible disintegration and dispersion profiles...

  2. Special issue on compact x-ray sources

    Science.gov (United States)

    Hooker, Simon; Midorikawa, Katsumi; Rosenzweig, James

    2014-04-01

    Journal of Physics B: Atomic, Molecular and Optical Physics is delighted to announce a forthcoming special issue on compact x-ray sources, to appear in the winter of 2014, and invites you to submit a paper. The potential for high-brilliance x- and gamma-ray sources driven by advanced, compact accelerators has gained increasing attention in recent years. These novel sources—sometimes dubbed 'fifth generation sources'—will build on the revolutionary advance of the x-ray free-electron laser (FEL). New radiation sources of this type have widespread applications, including in ultra-fast imaging, diagnostic and therapeutic medicine, and studies of matter under extreme conditions. Rapid advances in compact accelerators and in FEL techniques make this an opportune moment to consider the opportunities which could be realized by bringing these two fields together. Further, the successful development of compact radiation sources driven by compact accelerators will be a significant milestone on the road to the development of high-gradient colliders able to operate at the frontiers of particle physics. Thus the time is right to publish a peer-reviewed collection of contributions concerning the state-of-the-art in: advanced and novel acceleration techniques; sophisticated physics at the frontier of FELs; and the underlying and enabling techniques of high brightness electron beam physics. Interdisciplinary research connecting two or more of these fields is also increasingly represented, as exemplified by entirely new concepts such as plasma based electron beam sources, and coherent imaging with fs-class electron beams. We hope that in producing this special edition of Journal of Physics B: Atomic, Molecular and Optical Physics (iopscience.iop.org/0953-4075/) we may help further a challenging mission and ongoing intellectual adventure: the harnessing of newly emergent, compact advanced accelerators to the creation of new, agile light sources with unprecedented capabilities

  3. Soil compaction of various Central European forest soils caused by traffic of forestry machines with various chassis

    Directory of Open Access Journals (Sweden)

    Michal Allman

    2015-12-01

    Full Text Available Aim of study: The primary objective of this paper was to compare the effects of different types of forestry machine chassis on the compaction of the top layers of soil and to define the soil moisture content level, at which machine traffic results in maximum compaction.Area of study: Measurements were conducted in eight forest stands located in Slovakia and the Czech Republic. The soil types in the stands subjected to the study were luvisols, stagnosols, cambisols, and rendzinas.Material and Methods: The measurements were focused on tracked and wheeled (equipped with low pressure tyres cut-to-length machines, and skidders equipped with wide and standard tyres. The bulk density of soil was determined from soil samples extracted from the ruts, the centre of the skid trail, and the undisturbed stand. To determine soil moisture content, at which the soil is the most susceptible to compaction, the Proctor standard test was employed.Main results: The moisture content for maximal compaction fluctuated from 12% to 34.06%. Wheeled machines compacted the soil to 1.24 – 1.36 g.cm-3 (30.3 – 35.4 % compaction in dried state. Bulk density of soil in stands where tracked machine operated was lower, ranging from 1.02 to 1.06 g.cm-3 (25.3 % compaction.Research highlights: All wheeled machines caused the same amount of soil compaction in the ruts, despite differences in tyres, machine weight, etc. Maximum compaction caused by forestry machines occurred at minimal moisture contents, easily achievable in European climatic conditions.  Keywords: soil compaction; bulk density; soil moisture content limits; cut-to-length machines; skidders.

  4. Physical and mechanical properties of self-compacting concrete containing superplasticizer and metakaolin

    Science.gov (United States)

    Shahidan, Shahiron; Tayeh, Bassam A.; Jamaludin, A. A.; Bahari, N. A. A. S.; Mohd, S. S.; Zuki Ali, N.; Khalid, F. S.

    2017-11-01

    The development of concrete technology shows a variety of admixtures in concrete to produce special concrete. This includes the production of self-compacting concrete which is able to fill up all spaces, take formwork shapes and pass through congested reinforcement bars without vibrating or needing any external energy. In this study, the main objective is to compare the physical and mechanical properties of self-compacting concrete containing metakaolin with normal concrete. Four types of samples were produced to study the effect of metakaolin towards the physical and mechanical properties of self-compacting concrete where 0%, 5%, 10% and 15% of metakaolin were used as cement replacement. The physical properties were investigated using slump test for normal concrete and slump flow test for self-compacting concrete. The mechanical properties were tested for compressive strength and tensile strength. The findings of this study show that the inclusion of metakaolin as cement replacement can increase both compressive and tensile strength compared to normal concrete. The highest compressive strength was found in self-compacting concrete with 15% metakaolin replacement at 53.3 MPa while self-compacting concrete with 10% metakaolin replacement showed the highest tensile strength at 3.6 MPa. On top of that, the finishing or concrete surface of both cube and cylinder samples made of self-compacting concrete produced a smooth surface with the appearance of less honeycombs compared to normal concrete.

  5. Anisotropic Material Behavior of Uni-axially Compacted Graphite Matrix for HTGR Fuel Compact Fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young-Woo; Yeo, Seunghwan; Yoon, Ji-Hae; Cho, Moon Sung [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    In developing the fuel compact fabrication technology, and fuel graphite material to meet the required material properties, it is essential to investigate the relationship among the process parameters of the matrix graphite powder preparation, the fabrication parameters of fuel element green compact and the heat treatments conditions and the material properties of fuel element. It was observed, during this development, that the pressing technique employed for the compaction fabrication prior to the two successive heat treatments (carbonization and final high temperature heat treatment) was of extreme importance in determining the material properties of the final compact product. In this work, the material behavior of the uni-axially pressed graphite matrix during the carbonization and final heat treatment are evaluated and summarized along the different directions, viz., perpendicular and parallel directions to pressing direction. In this work, the dimensional variations and variations in thermal expansion, thermal conductivity and Vickers hardness of the graphite matrix compact samples in the axial and radial directions prepared by uni-axial pressing are evaluated, and compared with those of samples prepared by cold isostatic pressing with the available data. From this work, the followings are observed. 1) Dimensional changes of matrix graphite green compacts during carbonization show that the difference in radial and axial variations shows a large anisotropic behavior in shrinkage. The radial variation is very small while the axial variation is large. During carbonization, the stresses caused by the force would be released in to the axial direction together with the phenolic resin vapor. 2) Dimensional variation of compact samples in perpendicular and parallel directions during carbonization shows a large difference in behavior when compact sample is prepared by uni-axial pressing. However, when compact sample is prepared by cold isostatic pressing, there is

  6. Anisotropic Material Behavior of Uni-axially Compacted Graphite Matrix for HTGR Fuel Compact Fabrication

    International Nuclear Information System (INIS)

    Lee, Young-Woo; Yeo, Seunghwan; Yoon, Ji-Hae; Cho, Moon Sung

    2016-01-01

    In developing the fuel compact fabrication technology, and fuel graphite material to meet the required material properties, it is essential to investigate the relationship among the process parameters of the matrix graphite powder preparation, the fabrication parameters of fuel element green compact and the heat treatments conditions and the material properties of fuel element. It was observed, during this development, that the pressing technique employed for the compaction fabrication prior to the two successive heat treatments (carbonization and final high temperature heat treatment) was of extreme importance in determining the material properties of the final compact product. In this work, the material behavior of the uni-axially pressed graphite matrix during the carbonization and final heat treatment are evaluated and summarized along the different directions, viz., perpendicular and parallel directions to pressing direction. In this work, the dimensional variations and variations in thermal expansion, thermal conductivity and Vickers hardness of the graphite matrix compact samples in the axial and radial directions prepared by uni-axial pressing are evaluated, and compared with those of samples prepared by cold isostatic pressing with the available data. From this work, the followings are observed. 1) Dimensional changes of matrix graphite green compacts during carbonization show that the difference in radial and axial variations shows a large anisotropic behavior in shrinkage. The radial variation is very small while the axial variation is large. During carbonization, the stresses caused by the force would be released in to the axial direction together with the phenolic resin vapor. 2) Dimensional variation of compact samples in perpendicular and parallel directions during carbonization shows a large difference in behavior when compact sample is prepared by uni-axial pressing. However, when compact sample is prepared by cold isostatic pressing, there is

  7. Ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the Northern elephant seal (Mirounga angustirostris

    Directory of Open Access Journals (Sweden)

    Colby eMoore

    2014-06-01

    Full Text Available Northern elephant seals (Mirounga angustirostris (NES are known to be deep, long-duration divers and to sustain long-repeated patterns of breath-hold, or apnea. Some phocid dives remain within the bounds of aerobic metabolism, accompanied by physiological responses inducing lung compression, bradycardia and peripheral vasoconstriction. Current data suggest an absence of type IIb fibers in pinniped locomotory musculature. To date, no fiber type data exist for NES, a consummate deep diver. In this study, NES were biopsied in the wild. Ontogenetic changes in skeletal muscle were revealed through succinate dehydrogenase (SDH based fiber typing. Results indicated a predominance of uniformly shaped, large type I fibers and elevated myoglobin (Mb concentrations in the longissimus dorsi (LD muscle of adults. No type II muscle fibers were detected in any adult sampled. This was in contrast to the juvenile animals that demonstrated type II myosin in Western Blot analysis, indicative of an ontogenetic change in skeletal muscle with maturation. These data support previous hypotheses that the absence of type II fibers indicates reliance on aerobic metabolism during dives, as well as a depressed metabolic rate and low energy locomotion. We also suggest that the lack of type IIb fibers (adults may provide a protection against ischemia reperfusion (IR injury in vasoconstricted peripheral skeletal muscle.

  8. Platelet Glycoprotein IIb/IIIa Receptor Inhibition in Non-ST-Elevation Acute Coronary Syndromes : Early Benefit During Medical Treatment Only, With Additional Protection During Percutaneous Coronary Intervention

    NARCIS (Netherlands)

    K.M. Akkerhuis (Martijn); P. Théroux (Pierre); R.M. Califf (Robert); E.J. Topol (Eric); M.L. Simoons (Maarten); H. Boersma (Eric)

    1999-01-01

    textabstractBACKGROUND: Glycoprotein (GP) IIb/IIIa receptor blockers prevent life-threatening cardiac complications in patients with acute coronary syndromes without ST-segment elevation and protect against thrombotic complications associated with percutaneous coronary

  9. Weakly compact operators and interpolation

    OpenAIRE

    Maligranda, Lech

    1992-01-01

    The class of weakly compact operators is, as well as the class of compact operators, a fundamental operator ideal. They were investigated strongly in the last twenty years. In this survey, we have collected and ordered some of this (partly very new) knowledge. We have also included some comments, remarks and examples. The class of weakly compact operators is, as well as the class of compact operators, a fundamental operator ideal. They were investigated strongly in the last twenty years. I...

  10. The Entropy of Co-Compact Open Covers

    Directory of Open Access Journals (Sweden)

    Steven Bourquin

    2013-06-01

    Full Text Available Co-compact entropy is introduced as an invariant of topological conjugation for perfect mappings defined on any Hausdorff space (compactness and metrizability are not necessarily required. This is achieved through the consideration of co-compact covers of the space. The advantages of co-compact entropy include: (1 it does not require the space to be compact and, thus, generalizes Adler, Konheim and McAndrew’s topological entropy of continuous mappings on compact dynamical systems; and (2 it is an invariant of topological conjugation, compared to Bowen’s entropy, which is metric-dependent. Other properties of co-compact entropy are investigated, e.g., the co-compact entropy of a subsystem does not exceed that of the whole system. For the linear system, (R; f, defined by f(x = 2x, the co-compact entropy is zero, while Bowen’s entropy for this system is at least log 2. More generally, it is found that co-compact entropy is a lower bound of Bowen’s entropies, and the proof of this result also generates the Lebesgue Covering Theorem to co-compact open covers of non-compact metric spaces.

  11. Simplified compact containment BWR plant

    International Nuclear Information System (INIS)

    Heki, H.; Nakamaru, M.; Tsutagawa, M.; Hiraiwa, K.; Arai, K.; Hida, T.

    2004-01-01

    The reactor concept considered in this paper has a small power output, a compact containment and a simplified BWR configuration with comprehensive safety features. The Compact Containment Boiling Water Reactor (CCR), which is being developed with matured BWR technologies together with innovative systems/components, is expected to prove attractive in the world energy markets due to its flexibility in regard to both energy demands and site conditions, its high potential for reducing investment risk and its safety features facilitating public acceptance. The flexibility is achieved by CCR's small power output of 300 MWe class and capability of long operating cycle (refueling intervals). CCR is expected to be attractive from view point of investment due to its simplification/innovation in design such as natural circulation core cooling with the bottom located short core, internal upper entry control rod drives (CRDs) with ring-type dryers and simplified ECCS system with high pressure containment concept. The natural circulation core eliminates recirculation pumps and the maintenance of such pumps. The internal upper entry CRDs reduce the height of the reactor vessel (RPV) and consequently reduce the height of the primary containment vessel (PCV). The safety features mainly consist of large water inventory above the core without large penetration below the top of the core, passive cooling system by isolation condenser (IC), passive auto catalytic recombiner and in-vessel retention (IVR) capability. The large inventory increases the system response time in the case of design-base accidents, including loss of coolant accidents. The IC suppresses PCV pressure by steam condensation without any AC power. The recombiner decreases hydrogen concentration in the PCV in the case of a severe accident. Cooling the molten core inside the RPV if the core should be damaged by loss of core coolability could attain the IVR. The feasibility of CCR safety system has been confirmed by LOCA

  12. Development of Soil Compaction Analysis Software (SCAN Integrating a Low Cost GPS Receiver and Compactometer

    Directory of Open Access Journals (Sweden)

    Dongha Lee

    2012-02-01

    Full Text Available A software for soil compaction analysis (SCAN has been developed for evaluating the compaction states using the data from the GPS as well as a compactometer attached on the roller. The SCAN is distinguished from other previous software for intelligent compaction (IC in that it can use the results from various types of GPS positioning methods, and it also has an optimal structure for remotely managing the large amounts of data gathered from numerous rollers. For this, several methods were developed: (1 improving the accuracy of low cost GPS receiver’s positioning results; (2 modeling the trajectory of a moving roller using a GPS receiver’s results and linking it with the data from the compactometer; and (3 extracting the information regarding the compaction states of the ground from the modeled trajectory, using spatial analysis methods. The SCAN was verified throughout various field compaction tests, and it has been confirmed that it can be a very effective tool in evaluating field compaction states.

  13. Gauge equivalence of σ models with non-compact Grassmannian manifolds

    International Nuclear Information System (INIS)

    Kundu, A.

    1986-01-01

    The gauge equivalence (GE) of σ models associated with non-compact Grassmannian manifolds is investigated with emphasis on the necessary restrictions for the choice of gauge elements in such cases. The importance of GE in solving a non-linear system with the help of inverse scattering data of its gauge related counterpart is demonstrated. The gauge relations between generalised Landau-Lifshitz (LL) and non-linear Schroedinger (NLS) type equations and also between non-linear σ models and generalised 'sine-sinh-Gordon' equations for non-compact SU(p,q)/S(U(u,v) x U(s,t)) manifolds are established. Using H-gauge invariance of LL the GE is extended to some higher-order specific non-linear systems. The gauge connection among various LL and NLS equations are schematically represented. Along with the recovery of earlier results important new results, some with significant non-compact structures, are discovered. (author)

  14. LASL Compact Torus Program

    International Nuclear Information System (INIS)

    Linford, R.K.; Armstrong, W.T.; Bartsch, R.R.

    1981-01-01

    The Compact Torus (CT) concept includes any axisymmetric toroidal plasma configuration, which does not require the linking of any material through the hole in the torus. Thus, the magnet coils, vacuum vessel, etc., have a simple cylindrical or spherical geometry instead of the toroidal geometry required for Tokamaks and RFP's. This simplified geometry results in substantial engineering advantages in CT reactor embodiments while retaining the good confinement properties afforded by an axisymmetric toroidal plasma-field geometry. CT's can be classified into three major types by using the ion gyro radius rho/sub i/ and the magnitude of the maximum toroidal field B/sub tm/

  15. EAF Slag Aggregate in Roller-Compacted Concrete Pavement: Effects of Delay in Compaction

    Directory of Open Access Journals (Sweden)

    My Ngoc-Tra Lam

    2018-04-01

    Full Text Available This study investigates the effect of delay in compaction on the optimum moisture content and the mechanical propertie s (i.e., compressive strength, ultrasonic pulse velocity, splitting tensile strength, and modulus of elasticity of roller-compacted concrete pavement (RCCP made of electric arc furnace (EAF slag aggregate. EAF slag with size in the range of 4.75–19 mm was used to replace natural coarse aggregate in RCCP mixtures. A new mixing method was proposed for RCCP using EAF slag aggregate. The optimum moisture content of RCCP mixtures in this study was determined by a soil compaction method. The Proctor test assessed the optimum moisture content of mixtures at various time after mixing completion (i.e., 0, 15, 30, 60, and 90 min. Then, the effect of delay in compaction on the mechanical properties of RCCP mixtures at 28 days of age containing EAF slag aggregate was studied. The results presented that the negative effect on water content in the mixture caused by the higher water absorption characteristic of EAF slag was mitigated by the new mixing method. The optimum water content and maximum dry density of RCCP experience almost no effect from the delay in compaction. The compressive strength and splitting tensile strength of RCCP using EAF slag aggregate fulfilled the strength requirements for pavement with 90 min of delay in compaction.

  16. Investigation of HMA compactability using GPR technique

    Science.gov (United States)

    Plati, Christina; Georgiou, Panos; Loizos, Andreas

    2014-05-01

    In-situ field density is often regarded as one of the most important controls used to ensure that an asphalt pavement being placed is of high quality. The achieved density results from the effectiveness of the applied compaction mode on the Hot Mix Asphalt (HMA) layer. It is worthwhile mentioning that the proper compaction of HMA increases pavement fatigue life, decreases the amount of permanent deformation or rutting, reduces the amount of oxidation or aging, decreases moisture damage or stripping, increases strength and internal stability, and may decrease slightly the amount of low-temperature cracking that may occur in the mix. Conventionally, the HMA density in the field is assessed by direct destructive methods, including through the cutting of samples or drilling cores. These methods are characterized by a high accuracy, although they are intrusive and time consuming. In addition, they provide local information, i.e. information only for the exact test location. To overcome these limitations, the use of non-intrusive techniques is often recommended. The Ground Penetrating Radar (GPR) technique is an example of a non-intrusive technique that has been increasingly used for pavement investigations over the years. GPR technology is practical and application-oriented with the overall design concept, as well as the hardware, usually dependent on the target type and the material composing the target and its surroundings. As the sophistication of operating practices increases, the technology matures and GPR becomes an intelligent sensor system. The intelligent sensing deals with the expanded range of GPR applications in pavements such as determining layer thickness, detecting subsurface distresses, estimating moisture content, detecting voids and others. In addition, the practice of using GPR to predict in-situ field density of compacted asphalt mixture material is still under development and research; however the related research findings seem to be promising

  17. Phase distribution and microstructural changes of self-compacting cement paste at elevated temperature

    International Nuclear Information System (INIS)

    Ye, G.; Liu, X.; De Schutter, G.; Taerwe, L.; Vandevelde, P.

    2007-01-01

    Self-compacting concrete, as a new smart building material with various advanced properties, has been used for a wide range of structures and infrastructures. However little investigation have been reported on the properties of Self-compacting when it is exposed to elevated temperatures. Previous experiments on fire test have shown the differences between high performance concrete and traditional concrete at elevated temperature. This difference is largely depending on the microstructural properties of concrete matrix, i.e. the cement paste, especially on the porosity, pore size distribution and the connectivity of pores in cement pastes. In this contribution, the investigations are focused on the cement paste. The phase distribution and microstructural changes of self-compacting cement paste at elevated temperatures are examined by mercury intrusion porosimetry and scanning electron microscopy. The chemical decomposition of self-compacting cement paste at different temperatures is determined by thermogravimetric analysis. The experimental results of self-compacting cement paste are compared with those of high performance cement paste and traditional cement paste. It was found that self-compacting cement paste shows a higher change of the total porosity in comparison with high performance cement paste. When the temperature is higher than 700 deg. C, a dramatic loss of mass was observed in the self-compacting cement paste samples with addition of limestone filler. This implies that the SCC made by this type of self-compacting cement paste will probably show larger damage once exposed to fire. Investigation has shown that 0.5 kg/m 3 of Polypropylene fibers in the self-compacting cement paste can avoid the damage efficiently

  18. Popular heavy particle beam cancer therapeutic system (3). Development of high efficiency compact incident system-2. Great success of beam test of new APF-IH type DTL

    International Nuclear Information System (INIS)

    Yamamoto, Kazuo; Iwata, Yoshiyuki

    2006-01-01

    High efficiency compact incident system consists of an electron cyclotron resonance (ECR) ion source, a radio frequency quadrupole (RFQ) linear accelerator and an interdigital H-mode (IH) drift tube linear accelerator (DTL). IH type DTL and alternating phase focusing (APF) method is explained. Its special features, production, and beam test are reported. The electric field generation method, outline of the APF method, drift tube, IH type DTL, distribution of electric field and voltage, set up of beam test, ECR ion source and incident line, the inside structure of the RFQ type linear accelerator and the APF-IH type DTL, matching Q lens section, beam, emittance, measurement results of momentum dispersion are illustrated. (S.Y.)

  19. Genetic control over the processes of postirradiation recovery of a compact chromosome in micrococcus radiodurans

    International Nuclear Information System (INIS)

    Kudryashova, N.Yu.; Groshev, V.V.; Shestakov, S.V.

    1984-01-01

    X-irradiation of Micrococcus radiodurans cells with sublethal doses caused disturbances in the structure of a membrane-bound compact chromosome. Recovery of the compact chromosome occurred during the postirradiation incubation of the wild type cells and cells of the UVS-17 mutant deficient in DNA-polymerase. This process was blocked in cells of rec-30 mutant with the impaired system of genetic recombination: this is indicative of an important role played by rec-30 gene product in the postirradiation recovery of the compact chromosome in M. radiodurans cells

  20. Data on the influence of cold isostatic pre-compaction on mechanical properties of polycrystalline nickel sintered using Spark Plasma Sintering

    Directory of Open Access Journals (Sweden)

    Guy-Daniel Dutel

    2017-04-01

    Full Text Available Data regarding bulk polycrystalline nickel samples obtained by powder metallurgy using Spark Plasma Sintering (SPS are presented, with a special emphasis on the influence of a cold isostatic pre-compaction on the resulting morphologies and subsequent mechanical properties. Three types of initial powders are used, nanometric powders, micrometric powders and a mixture of the formers. For each type of powder, the SPS cycle has been optimized for the powders without pre-compaction and the same cycle has been used to also sinter pre-compacted powders.

  1. Diverse Formation Mechanisms for Compact Galaxies

    Science.gov (United States)

    Kim, Jin-Ah; Paudel, Sanjaya; Yoon, Suk-Jin

    2018-01-01

    Compact, quenched galaxies such as M32 are unusual ones located off the mass - size scaling relation defined by normal galaxies. Still, their formation mechanisms remain unsolved. Here we investigate the evolution of ~100 compact, quenched galaxies at z = 0 identified in the Illustris cosmological simulation. We identify three ways for a galaxy to become a compact one and, often, multiple mechanisms operate in a combined manner. First, stripping is responsible for making about a third of compact galaxies. Stripping removes stars from galaxies, usually while keeping their sizes intact. About one third are galaxies that cease their growth early on after entering into more massive, gigantic halos. Finally, about half of compact galaxies, ~ 35 % of which turn out to undergo stripping, experience the compaction due to the highly centrally concentrated star formation. We discuss the evolutionary path of compact galaxies on the mass – size plane for each mechanism in a broader context of dwarf galaxy formation and evolution.

  2. Experimental study on swelling character of statics-compacted bentonite-sand mixture

    International Nuclear Information System (INIS)

    Cui Suli; Zhang Huyuan; Liu Jisheng; Liang Jian

    2010-01-01

    In the high-level radioactive waste (HLW) geological disposal projects barrier system, there are two types for constructing buffer/backfill material in preconceived: locale field-pressed and locale-build by prefab lock. Statics-Compacted is needed for both footrill padding in the locale field-pressed and locale-build by prefab lock. Laboratory tests were conducted on statics-compacted mixture of GMZ001 bentonite and quartz sand in different addition. The results obtained indicated that in the semi-log coordinates, the form of the P-time and e-time curves were sigmoid,the same as dynamic-compacted specime. The swelling character of statics-compacted specime were also as well as dynamic-compacted specime, that is with the increase of initial dry density, the maximum swelling pressure were exponential increase and maximum swelling strain increase linearly. These made it clear that the methods of making specime have no effect on the swelling character of bentonite-sand mixture, so methods for constructing buffer/backfill material can be selected free as needed in the construction site. The validity of regression relationship received by dynamic-compacted specime test was verified, and the coefficients for the regression equation were revised in a greater range of initial dry density. Based on the comprehensive analysis of experimental results, it is concluded that addition of 10-30% quartz sand and 1.60-1.80 g/cm 3 for initial dry density to GMZ001 bentonite-sand mixture is suitable for the swelling quality. (authors)

  3. Experimental studies of compact toroids

    International Nuclear Information System (INIS)

    1991-01-01

    The Berkeley Compact Toroid Experiment (BCTX) device is a plasma device with a Marshall-gun generated, low aspect ratio toroidal plasma. The device is capable of producing spheromak-type discharges and may, with some modification, produce low-aspect ratio tokamak configurations. A unique aspect of this experimenal devie is its large lower hybrid (LH) heating system, which consists of two 450MHz klystron tubes generating 20 megawatts each into a brambilla-type launching structure. Successful operation with one klystron at virtually full power (18 MW) has been accomplished with 110 μs pulse length. A second klystron is currently installed in its socket and magnet but has not been added to the RF drive system. This report describes current activities and accomplishments and describes the anticipated results of next year's activity

  4. Compact Process Development at Babcock & Wilcox

    Energy Technology Data Exchange (ETDEWEB)

    Eric Shaber; Jeffrey Phillips

    2012-03-01

    Multiple process approaches have been used historically to manufacture cylindrical nuclear fuel compacts. Scale-up of fuel compacting was required for the Next Generation Nuclear Plant (NGNP) project to achieve an economically viable automated production process capable of providing a minimum of 10 compacts/minute with high production yields. In addition, the scale-up effort was required to achieve matrix density equivalent to baseline historical production processes, and allow compacting at fuel packing fractions up to 46% by volume. The scale-up approach of jet milling, fluid-bed overcoating, and hot-press compacting adopted in the U.S. Advanced Gas Reactor (AGR) Fuel Development Program involves significant paradigm shifts to capitalize on distinct advantages in simplicity, yield, and elimination of mixed waste. A series of compaction trials have been completed to optimize compaction conditions of time, temperature, and forming pressure using natural uranium oxycarbide (NUCO) fuel at packing fractions exceeding 46% by volume. Results from these trials are included. The scale-up effort is nearing completion with the process installed and operable using nuclear fuel materials. Final process testing is in progress to certify the process for manufacture of qualification test fuel compacts in 2012.

  5. Fracture toughness measurements with subsize disk compact specimens

    International Nuclear Information System (INIS)

    Alexander, D.J.

    1994-01-01

    Special fixtures and test methods have been developed for testing small disk compact specimens (1.25 mm diam by 4.6 mm thick). Specimens of European type 316L austenitic stainless steel were irradiated to damage levels of about 3 dpa at nominal irradiation temperatures of either 90 or 250 C and tested over a temperature range from 20 to 250 C. Results show that irradiation to this dose level at these temperatures reduces the fracture toughness but the toughness remains quite high. The toughness decreases as the test temperature increases. Irradiation at 250 C is more damaging than at 90 C, causing larger decreases in the fracture toughness. The testing shows that it is possible to generate useful fracture toughness data with a small disk compact specimens

  6. Compact magnetic confinement fusion: Spherical torus and compact torus

    Directory of Open Access Journals (Sweden)

    Zhe Gao

    2016-05-01

    Full Text Available The spherical torus (ST and compact torus (CT are two kinds of alternative magnetic confinement fusion concepts with compact geometry. The ST is actually a sub-category of tokamak with a low aspect ratio; while the CT is a toroidal magnetic configuration with a simply-connected geometry including spheromak and field reversed pinch. The ST and CT have potential advantages for ultimate fusion reactor; while at present they can also provide unique fusion science and technology contributions for mainstream fusion research. However, some critical scientific and technology issues should be extensively investigated.

  7. Compact stars

    Science.gov (United States)

    Estevez-Delgado, Gabino; Estevez-Delgado, Joaquin

    2018-05-01

    An analysis and construction is presented for a stellar model characterized by two parameters (w, n) associated with the compactness ratio and anisotropy, respectively. The reliability range for the parameter w ≤ 1.97981225149 corresponds with a compactness ratio u ≤ 0.2644959374, the density and pressures are positive, regular and monotonic decrescent functions, the radial and tangential speed of sound are lower than the light speed, moreover, than the plausible stability. The behavior of the speeds of sound are determinate for the anisotropy parameter n, admitting a subinterval where the speeds are monotonic crescent functions and other where we have monotonic decrescent functions for the same speeds, both cases describing a compact object that is also potentially stable. In the bigger value for the observational mass M = 2.05 M⊙ and radii R = 12.957 Km for the star PSR J0348+0432, the model indicates that the maximum central density ρc = 1.283820319 × 1018 Kg/m3 corresponds to the maximum value of the anisotropy parameter and the radial and tangential speed of the sound are monotonic decrescent functions.

  8. A compact PE memory for vision chips

    Science.gov (United States)

    Cong, Shi; Zhe, Chen; Jie, Yang; Nanjian, Wu; Zhihua, Wang

    2014-09-01

    This paper presents a novel compact memory in the processing element (PE) for single-instruction multiple-data (SIMD) vision chips. The PE memory is constructed with 8 × 8 register cells, where one latch in the slave stage is shared by eight latches in the master stage. The memory supports simultaneous read and write on the same address in one clock cycle. Its compact area of 14.33 μm2/bit promises a higher integration level of the processor. A prototype chip with a 64 × 64 PE array is fabricated in a UMC 0.18 μm CMOS technology. Five types of the PE memory cell structure are designed and compared. The testing results demonstrate that the proposed PE memory architecture well satisfies the requirement of the vision chip in high-speed real-time vision applications, such as 1000 fps edge extraction.

  9. A compact PE memory for vision chips

    International Nuclear Information System (INIS)

    Shi Cong; Chen Zhe; Yang Jie; Wu Nanjian; Wang Zhihua

    2014-01-01

    This paper presents a novel compact memory in the processing element (PE) for single-instruction multiple-data (SIMD) vision chips. The PE memory is constructed with 8 × 8 register cells, where one latch in the slave stage is shared by eight latches in the master stage. The memory supports simultaneous read and write on the same address in one clock cycle. Its compact area of 14.33 μm 2 /bit promises a higher integration level of the processor. A prototype chip with a 64 × 64 PE array is fabricated in a UMC 0.18 μm CMOS technology. Five types of the PE memory cell structure are designed and compared. The testing results demonstrate that the proposed PE memory architecture well satisfies the requirement of the vision chip in high-speed real-time vision applications, such as 1000 fps edge extraction. (semiconductor integrated circuits)

  10. Index theory for locally compact noncommutative geometries

    CERN Document Server

    Carey, A L; Rennie, A; Sukochev, F A

    2014-01-01

    Spectral triples for nonunital algebras model locally compact spaces in noncommutative geometry. In the present text, the authors prove the local index formula for spectral triples over nonunital algebras, without the assumption of local units in our algebra. This formula has been successfully used to calculate index pairings in numerous noncommutative examples. The absence of any other effective method of investigating index problems in geometries that are genuinely noncommutative, particularly in the nonunital situation, was a primary motivation for this study and the authors illustrate this point with two examples in the text. In order to understand what is new in their approach in the commutative setting the authors prove an analogue of the Gromov-Lawson relative index formula (for Dirac type operators) for even dimensional manifolds with bounded geometry, without invoking compact supports. For odd dimensional manifolds their index formula appears to be completely new.

  11. Roller-compacted concrete pavements.

    Science.gov (United States)

    2010-09-01

    Roller-compacted concrete (RCC) gets its name from the heavy vibratory steel drum and rubber-tired rollers used to help compact it into its final form. RCC has similar strength properties and consists of the same basic ingredients as conventional con...

  12. Structural characterization of the PTS IIA and IIB proteins associated with pneumococcal fucose utilization.

    Science.gov (United States)

    Higgins, Melanie A; Hamilton, Aileen M; Boraston, Alisdair B

    2017-05-01

    Streptococcus pneumoniae harbors a significant number of transporters, including phosphotransferase (PTS) systems, allowing the bacterium to utilize a number of different carbohydrates for metabolic and other purposes. The genes encoding for one PTS transport system in particular (EII fuc ) are found within a fucose utilization operon in S. pneumoniae TIGR4. Here, we report the three-dimensional structures of IIA fuc and IIB fuc providing evidence that this PTS system belongs to the EII man family. Additionally, the predicted metabolic pathway for this distinctive fucose utilization system suggests that EII fuc transports the H-disaccharide blood group antigen, which would represent a novel PTS transporter specificity. Proteins 2017; 85:963-968. © 2016 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  13. Modulus of smoothness and theorems concerning approximation on compact groups

    Directory of Open Access Journals (Sweden)

    H. Vaezi

    2003-01-01

    Full Text Available We consider the generalized shift operator defined by (Shuf(g=∫Gf(tut−1gdt on a compact group G, and by using this operator, we define “spherical” modulus of smoothness. So, we prove Stechkin and Jackson-type theorems.

  14. Spectrometers for compact neutron sources

    Science.gov (United States)

    Voigt, J.; Böhm, S.; Dabruck, J. P.; Rücker, U.; Gutberlet, T.; Brückel, T.

    2018-03-01

    We discuss the potential for neutron spectrometers at novel accelerator driven compact neutron sources. Such a High Brilliance Source (HBS) relies on low energy nuclear reactions, which enable cryogenic moderators in very close proximity to the target and neutron optics at comparably short distances from the moderator compared to existing sources. While the first effect aims at increasing the phase space density of a moderator, the second allows the extraction of a large phase space volume, which is typically requested for spectrometer applications. We find that competitive spectrometers can be realized if (a) the neutron production rate can be synchronized with the experiment repetition rate and (b) the emission characteristics of the moderator can be matched to the phase space requirements of the experiment. MCNP simulations for protons or deuterons on a Beryllium target with a suitable target/moderator design yield a source brightness, from which we calculate the sample fluxes by phase space considerations for different types of spectrometers. These match closely the figures of todays spectrometers at medium flux sources. Hence we conclude that compact neutron sources might be a viable option for next generation neutron sources.

  15. A phase IIb multicentre study comparing the efficacy of trabectedin to doxorubicin in patients with advanced or metastatic untreated soft tissue sarcoma: The TRUSTS trial

    NARCIS (Netherlands)

    Bui-Nguyen, B.; Butrynski, J.E.; Penel, N.; Blay, J.Y.; Isambert, N.; Milhem, M.; Kerst, J.M.; Reyners, A.K.; Litiere, S.; Marreaud, S.; Collin, F.; Graaf, W.T.A. van der

    2015-01-01

    PURPOSE: To evaluate whether trabectedin as first-line chemotherapy for advanced/metastatic soft tissue sarcoma prolongs progression-free survival (PFS), compared to doxorubicin and, in the phase IIb part here, to select the most appropriate trabectedin treatment schedule (3-hour or 24-hour

  16. The Lω-Compactness in Lω-Spaces

    Directory of Open Access Journals (Sweden)

    Shui-Li Chen

    2013-01-01

    Full Text Available The concepts of αω-remote neighborhood family, γω-cover, and Lω-compactness are defined in Lω-spaces. The characterizations of Lω-compactness are systematically discussed. Some important properties of Lω-compactness such as ω-closed heredity, arbitrarily multiplicative property, and preserving invariance under ω-continuous mappings are obtained. Finally, the Alexander ω-subbase lemma and the Tychonoff product theorem with respect to Lω-compactness are given.

  17. UV written compact broadband optical couplers

    DEFF Research Database (Denmark)

    Olivero, Massimo; Svalgaard, Mikael

    2005-01-01

    In this paper the first demonstration of compact asymmetric directional couplers made by UV writing is presented. The combined performance in terms bandwidth, loss and compactness exceeds that reported using other, more elaborate fabrication techniques.......In this paper the first demonstration of compact asymmetric directional couplers made by UV writing is presented. The combined performance in terms bandwidth, loss and compactness exceeds that reported using other, more elaborate fabrication techniques....

  18. Prediction of reservoir compaction and surface subsidence

    Energy Technology Data Exchange (ETDEWEB)

    De Waal, J.A.; Smits, R.M.M.

    1988-06-01

    A new loading-rate-dependent compaction model for unconsolidated clastic reservoirs is presented that considerably improves the accuracy of predicting reservoir rock compaction and surface subsidence resulting from pressure depletion in oil and gas fields. The model has been developed on the basis of extensive laboratory studies and can be derived from a theory relating compaction to time-dependent intergranular friction. The procedure for calculating reservoir compaction from laboratory measurements with the new model is outlined. Both field and laboratory compaction behaviors appear to be described by one single normalized, nonlinear compaction curve. With the new model, the large discrepancies usually observed between predictions based on linear compaction models and actual (nonlinear) field behavior can be explained.

  19. Detection de la fin de la compaction des anodes par le son

    Science.gov (United States)

    Sanogo, Bazoumana

    L'objectif de ce projet etait de developper un outil de controle en temps reel du temps de compaction en se servant du son genere par le vibrocompacteur pendant le formage des anodes crues. Ainsi, une application a ete developpee pour l'analyse des sons enregistres. Des essais ont ete realises avec differents microphones pour une meilleure qualite des mesures et un a ete choisi pour la suite du projet. De meme, differents tests ont ete realises sur des anodes de laboratoire ainsi que des anodes a l'echelle industrielle afin de mettre en place une methode pour la detection du temps optimal necessaire au formage des anodes. Les travaux au laboratoire de carbone a l'Universite du Quebec a Chicoutimi (UQAC) ont consiste a l'enregistrement de son des anodes fabriquees sur place avec differentes configurations; et a la caracterisation de certaines anodes de l'usine. Les anodes fabriquees au laboratoire sont reparties en deux groupes. Le premier regroupe les anodes pour la validation de notre methode. Ce sont des anodes produites avec des temps de compaction differents. Le laboratoire de carbone a l'UQAC est unique et il est possible de produire des anodes avec les memes proprietes que celles des anodes industrielles. Par consequent, la validation initialement prevue a l'usine a ete effectuee avec les anodes de laboratoire. Le deuxieme groupe a servi a etudier les effets des matieres premieres sur le temps de compaction. Le type de coke et le type de brai ont constitue les differentes variations dans ce deuxieme groupe. Quant aux tests et mesures a l'usine, ils ont ete realises en trois campagnes de mesure. La premiere campagne en juin 2014 a servi a standardiser et a trouver le meilleur positionnement des appareils pour les mesures, a regler le logiciel et a faire les premieres mesures. Une deuxieme campagne en mai 2015 a fait l'objet d'enregistrement de son en classant les anodes selon differents temps de compaction. La troisieme et derniere campagne en decembre 2015 a

  20. Phased array compaction cell for measurement of the transversely isotropic elastic properties of compacting sediments

    Energy Technology Data Exchange (ETDEWEB)

    Nihei, K.T.; Nakagawa, S.; Reverdy, F.; Meyer, L.R.; Duranti, L.; Ball, G.

    2010-12-15

    Sediments undergoing compaction typically exhibit transversely isotropic (TI) elastic properties. We present a new experimental apparatus, the phased array compaction cell, for measuring the TI elastic properties of clay-rich sediments during compaction. This apparatus uses matched sets of P- and S-wave ultrasonic transducers located along the sides of the sample and an ultrasonic P-wave phased array source, together with a miniature P-wave receiver on the top and bottom ends of the sample. The phased array measurements are used to form plane P-waves that provide estimates of the phase velocities over a range of angles. From these measurements, the five TI elastic constants can be recovered as the sediment is compacted, without the need for sample unloading, recoring, or reorienting. This paper provides descriptions of the apparatus, the data processing, and an application demonstrating recovery of the evolving TI properties of a compacting marine sediment sample.

  1. Supersymmetric RG flows and Janus from type II orbifold compactification

    Energy Technology Data Exchange (ETDEWEB)

    Karndumri, Parinya; Upathambhakul, Khem [Chulalongkorn University, String Theory and Supergravity Group, Department of Physics, Faculty of Science, Bangkok (Thailand)

    2017-07-15

    We study holographic RG flow solutions within four-dimensional N = 4 gauged supergravity obtained from type IIA and IIB string theories compactified on T{sup 6}/Z{sub 2} x Z{sub 2} orbifold with gauge, geometric and non-geometric fluxes. In type IIB non-geometric compactifications, the resulting gauged supergravity has ISO(3) x ISO(3) gauge group and admits an N = 4 AdS{sub 4} vacuum dual to an N = 4 superconformal field theory (SCFT) in three dimensions. We study various supersymmetric RG flows from this N = 4 SCFT to N = 4 and N = 1 non-conformal field theories in the IR. The flows preserving N = 4 supersymmetry are driven by relevant operators of dimensions Δ = 1, 2 or alternatively by one of these relevant operators, dual to the dilaton, and irrelevant operators of dimensions Δ = 4 while the N = 1 flows in addition involve marginal deformations. Most of the flows can be obtained analytically. We also give examples of supersymmetric Janus solutions preserving N = 4 and N = 1 supersymmetries. These solutions should describe two-dimensional conformal defects within the dual N = 4 SCFT. Geometric compactifications of type IIA theory give rise to N = 4 gauged supergravity with ISO(3) x U(1){sup 6} gauge group. In this case, the resulting gauged supergravity admits an N = 1 AdS{sub 4} vacuum. We also numerically study possible N = 1 RG flows to non-conformal field theories in this case. (orig.)

  2. Holographic duals of 3d S-fold CFTs arXiv

    CERN Document Server

    Assel, Benjamin

    We construct non-geometric AdS$_4$ solutions of IIB string theory where the fields in overlapping patches are glued by elements of the S-duality group. We obtain them by suitable quotients of compact and non-compact geometric solutions. The quotient procedure suggests CFT duals as quiver theories with links involving the so-called $T[U(N)]$ theory. We test the validity of the non-geometric solutions (and of our proposed holographic duality) by computing the three-sphere partition function $Z$ of the CFTs. A first class of solutions is obtained by an S-duality quotient of Janus-type non-compact solutions and is dual to 3d $\\mathcal{N}=4$ SCFTs; for these we manage to compute $Z$ of the dual CFT at finite $N$, and it agrees perfectly with the supergravity result in the large $N$ limit. A second class has five-branes, it is obtained by a M\\"obius-like S-quotient of ordinary compact solutions and is dual to 3d $\\mathcal{N}=3$ SCFTs. For these, $Z$ agrees with the supergravity result if one chooses the limit caref...

  3. Large-scale dynamic compaction of natural salt

    International Nuclear Information System (INIS)

    Hansen, F.D.; Ahrens, E.H.

    1996-01-01

    A large-scale dynamic compaction demonstration of natural salt was successfully completed. About 40 m 3 of salt were compacted in three, 2-m lifts by dropping a 9,000-kg weight from a height of 15 m in a systematic pattern to achieve desired compaction energy. To enhance compaction, 1 wt% water was added to the relatively dry mine-run salt. The average compacted mass fractional density was 0.90 of natural intact salt, and in situ nitrogen permeabilities averaged 9X10 -14 m 2 . This established viability of dynamic compacting for placing salt shaft seal components. The demonstration also provided compacted salt parameters needed for shaft seal system design and performance assessments of the Waste Isolation Pilot Plant

  4. Gas separation performance of a hollow-filament type polyimide membrane module for a compact tritium removal system

    International Nuclear Information System (INIS)

    Hayashi, Takumi; Yamada, Masayuki; Suzuki, Takumi; Matsuda, Yuji; Okuno, Kenji

    1995-01-01

    A new tritium removal system using gas separation membranes has been studied to develop more compact and cost-effective system for a fusion reactor. To obtain necessary parameters, which are directly scalable to the ITER Atmospheric Detritiation System, the basic tritium recovery performance was investigated with a scaled polyimide membrane module (hollow-filament type : 10 m 3 /hr) loop. The result shows that the H 2 recovery ratio from N 2 or air was more than 99% or about 97%, respectively, at flow rate ratio of permeated/feed = 0.1, feed ampersand permeated side pressures = 2580 ampersand 80 torr, and module temp. = 293 K. Tritium (HT) recovery function was almost the same as H 2 recovery, even though the total hydrogen concentration was a few ppm in the feed of module. H 2 O recovery performance was better than hydrogen recovery. These recovery functions were improved effectively decreasing the pressure ratio of permeated/feed of module. 5 refs., 11 figs

  5. Compact hybrid cell based on a convoluted nanowire structure for harvesting solar and mechanical energy

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Chen; Wang, Zhong Lin [School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA 30332 (United States)

    2011-02-15

    A fully integrated, solid-state, compact hybrid cell (CHC) that comprises ''convoluted'' ZnO nanowire structures for concurrent harvesting of both solar and mechanical energy is demonstrated. The compact hybrid cell is based on a conjunction design of an organic solid-state dye-sensitized solar cell (DSSC) and piezoelectric nanogenerator in one compact structure. The CHC shows a significant increase in output power, clearly demonstrating its potential for simultaneously harvesting multiple types of energy for powering small electronic devices for independent, sustainable, and mobile operation. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  6. Flow simulation of fiber reinforced self compacting concrete using Lattice Boltzmann method

    DEFF Research Database (Denmark)

    Svec, Oldrich; Skocek, Jan; Stang, Henrik

    2011-01-01

    Self compacting concrete (SCC) is a promising material in the civil engineering industry. One of the benefits of the SCC is a fast and simplified casting followed by decreased labor costs. The SCC as any other type of concrete has a significantly lower tensile and shear strength in comparison to ....... A relatively new group of models - Lattice Boltzmann Modeling (LBM) - is presented in this paper. The conventional LBM is modified to include fiber and particle suspensions and non-Newtonian rheology and is used to model the fiber reinforced self compacting concrete flow....

  7. Quantitative Compactness Estimates for Hamilton-Jacobi Equations

    Science.gov (United States)

    Ancona, Fabio; Cannarsa, Piermarco; Nguyen, Khai T.

    2016-02-01

    We study quantitative compactness estimates in {W^{1,1}_{loc}} for the map {S_t}, {t > 0} that is associated with the given initial data {u_0in Lip (R^N)} for the corresponding solution {S_t u_0} of a Hamilton-Jacobi equation u_t+Hbig(nabla_{x} ubig)=0, qquad t≥ 0,quad xinR^N, with a uniformly convex Hamiltonian {H=H(p)}. We provide upper and lower estimates of order {1/\\varepsilon^N} on the Kolmogorov {\\varepsilon}-entropy in {W^{1,1}} of the image through the map S t of sets of bounded, compactly supported initial data. Estimates of this type are inspired by a question posed by Lax (Course on Hyperbolic Systems of Conservation Laws. XXVII Scuola Estiva di Fisica Matematica, Ravello, 2002) within the context of conservation laws, and could provide a measure of the order of "resolution" of a numerical method implemented for this equation.

  8. Development of the RF cavity for the SKKUCY-9 compact cyclotron

    International Nuclear Information System (INIS)

    Shin, Seungwook; Lee, Jongchul; LEE, Byeong-No; Ha, Donghyup; Namgoong, Ho; Chai, Jongseo

    2015-01-01

    A 9 MeV compact cyclotron, named SKKUCY-9, for a radiopharmaceutical compound especially fludeoxyglucose (FDG) production for a positron emission tomography (PET) machine was developed at Sungkyunkwan University. H − ions which are produced from a Penning Ionization Gauge(PIG) ion source, travel through a normal conducting radio frequency (RF) cavity which operates at 83.2 MHz for an acceleration and electro-magnet for a beam focusing until the ions acquire energy of about 9 MeV. For installation at a small local hospital, our SKKUCY-9 cyclotron is developed to be compact and light-weight, comparable to conventional medical purpose cyclotrons. For compactness, we adapted a deep valley and large angle hill type for the electro-magnet design. Normally a RF cavity is installed inside of the empty space of the magnet valley region, which is extremely small in our case. We faced problems such as difficulties of installing the RF cavity, low Q-value. Despite of those difficulties, a compact RF cavity and its system including a RF power coupler to feed amplified RF power to the RF cavity and a fine tuner to compensate RF frequency variations was successfully developed and tested

  9. Development of the RF cavity for the SKKUCY-9 compact cyclotron

    Science.gov (United States)

    Shin, Seungwook; Lee, Jongchul; LEE, Byeong-No; Ha, Donghyup; Namgoong, Ho; Chai, Jongseo

    2015-09-01

    A 9 MeV compact cyclotron, named SKKUCY-9, for a radiopharmaceutical compound especially fludeoxyglucose (FDG) production for a positron emission tomography (PET) machine was developed at Sungkyunkwan University. H- ions which are produced from a Penning Ionization Gauge(PIG) ion source, travel through a normal conducting radio frequency (RF) cavity which operates at 83.2 MHz for an acceleration and electro-magnet for a beam focusing until the ions acquire energy of about 9 MeV. For installation at a small local hospital, our SKKUCY-9 cyclotron is developed to be compact and light-weight, comparable to conventional medical purpose cyclotrons. For compactness, we adapted a deep valley and large angle hill type for the electro-magnet design. Normally a RF cavity is installed inside of the empty space of the magnet valley region, which is extremely small in our case. We faced problems such as difficulties of installing the RF cavity, low Q-value. Despite of those difficulties, a compact RF cavity and its system including a RF power coupler to feed amplified RF power to the RF cavity and a fine tuner to compensate RF frequency variations was successfully developed and tested.

  10. Physical and mechanical behaviour of a roller compacted concrete ...

    African Journals Online (AJOL)

    In order to study the behaviour of a roller compacted concrete (RCC) reinforced with polypropylene fiber, six types of RCC were made with different content of fibers (0, 0.5, 1, 1.5, 2 and 2.5 Kg/m3). The physical parameters are the density, the workability, the shrinkage and the water absorption. For the mechanical ...

  11. Soil compaction and growth of woody plants

    Energy Technology Data Exchange (ETDEWEB)

    Kozlowski, T.T. [Univ. of California, Berkeley (United States). Dept. of Environmental Science, Policy and Management

    1999-07-01

    Although soil compaction in the field may benefit or inhibit the growth of plants, the harmful effects are much more common. This paper emphasizes the deleterious effects of predominantly high levels of soil compaction on plant growth and yield. High levels of soil compaction are common in heavily used recreation areas, construction sites, urban areas, timber harvesting sites, fruit orchards, agroforestry systems and tree nurseries. Compaction can occur naturally by settling or slumping of soil or may be induced by tillage tools, heavy machinery, pedestrian traffic, trampling by animals and fire. Compaction typically alters soil structure and hydrology by increasing soil bulk density; breaking down soil aggregates; decreasing soil porosity, aeration and infiltration capacity; and by increasing soil strength, water runoff and soil erosion. Appreciable compaction of soil leads to physiological dysfunctions in plants. Often, but not always, reduced water absorption and leaf water deficits develop. Soil compaction also induces changes in the amounts and balances of growth hormones in plants, especially increases in abscisic acid and ethylene. Absorption of the major mineral nutrients is reduced by compaction of both surface soils and subsoils. The rate of photosynthesis of plants growing in very compacted soil is decreased by both stomatal and non-stomatal inhibition. Total photosynthesis is reduced as a result of smaller leaf areas. As soils become increasingly compacted respiration of roots shifts toward an anaerobic state. Severe soil compaction adversely influences regeneration of forest stands by inhibiting seed germination and growth of seedlings, and by inducing seedling mortality. Growth of woody plants beyond the seedling stage and yields of harvestable plant products also are greatly decreased by soil compaction because of the combined effects of high soil strength, decreased infiltration of water and poor soil aeration, all of which lead to a decreased

  12. Soil compaction and growth of woody plants

    International Nuclear Information System (INIS)

    Kozlowski, T.T.

    1999-01-01

    Although soil compaction in the field may benefit or inhibit the growth of plants, the harmful effects are much more common. This paper emphasizes the deleterious effects of predominantly high levels of soil compaction on plant growth and yield. High levels of soil compaction are common in heavily used recreation areas, construction sites, urban areas, timber harvesting sites, fruit orchards, agroforestry systems and tree nurseries. Compaction can occur naturally by settling or slumping of soil or may be induced by tillage tools, heavy machinery, pedestrian traffic, trampling by animals and fire. Compaction typically alters soil structure and hydrology by increasing soil bulk density; breaking down soil aggregates; decreasing soil porosity, aeration and infiltration capacity; and by increasing soil strength, water runoff and soil erosion. Appreciable compaction of soil leads to physiological dysfunctions in plants. Often, but not always, reduced water absorption and leaf water deficits develop. Soil compaction also induces changes in the amounts and balances of growth hormones in plants, especially increases in abscisic acid and ethylene. Absorption of the major mineral nutrients is reduced by compaction of both surface soils and subsoils. The rate of photosynthesis of plants growing in very compacted soil is decreased by both stomatal and non-stomatal inhibition. Total photosynthesis is reduced as a result of smaller leaf areas. As soils become increasingly compacted respiration of roots shifts toward an anaerobic state. Severe soil compaction adversely influences regeneration of forest stands by inhibiting seed germination and growth of seedlings, and by inducing seedling mortality. Growth of woody plants beyond the seedling stage and yields of harvestable plant products also are greatly decreased by soil compaction because of the combined effects of high soil strength, decreased infiltration of water and poor soil aeration, all of which lead to a decreased

  13. Microscopic analysis of irradiated AGR-1 coated particle fuel compacts

    Energy Technology Data Exchange (ETDEWEB)

    Ploger, Scott A., E-mail: scott.ploger@inl.gov [Idaho National Laboratory, P.O. Box 1625, Idaho Falls, ID 83415-3855 (United States); Demkowicz, Paul A. [Idaho National Laboratory, P.O. Box 1625, Idaho Falls, ID 83415-3855 (United States); Hunn, John D.; Kehn, Jay S. [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831-6093 (United States)

    2014-05-01

    The AGR-1 experiment involved irradiation of 72 TRISO-coated particle fuel compacts to a peak compact-average burnup of 19.5% FIMA with no in-pile failures observed out of 3 × 10{sup 5} total particles. Irradiated AGR-1 fuel compacts have been cross-sectioned and analyzed with optical microscopy to characterize kernel, buffer, and coating behavior. Six compacts have been examined, spanning a range of irradiation conditions (burnup, fast fluence, and irradiation temperature) and including all four TRISO coating variations irradiated in the AGR-1 experiment. The cylindrical specimens were sectioned both transversely and longitudinally, then polished to expose from 36 to 79 individual particles near midplane on each mount. The analysis focused primarily on kernel swelling and porosity, buffer densification and fracturing, buffer–IPyC debonding, and fractures in the IPyC and SiC layers. Characteristic morphologies have been identified, 981 particles have been classified, and spatial distributions of particle types have been mapped. No significant spatial patterns were discovered in these cross sections. However, some trends were found between morphological types and certain behavioral aspects. Buffer fractures were found in 23% of the particles, and these fractures often resulted in unconstrained kernel protrusion into the open cavities. Fractured buffers and buffers that stayed bonded to IPyC layers appear related to larger pore size in kernels. Buffer–IPyC interface integrity evidently factored into initiation of rare IPyC fractures. Fractures through part of the SiC layer were found in only four classified particles, all in conjunction with IPyC–SiC debonding. Compiled results suggest that the deliberate coating fabrication variations influenced the frequencies of IPyC fractures and IPyC–SiC debonds.

  14. Small Valdivia compact spaces

    CERN Document Server

    Kubi's, W; Kubi\\'s, Wieslaw; Michalewski, Henryk

    2005-01-01

    We prove a preservation theorem for the class of Valdivia compact spaces, which involves inverse sequences of ``simple'' retractions. Consequently, a compact space of weight $\\loe\\aleph_1$ is Valdivia compact iff it is the limit of an inverse sequence of metric compacta whose bonding maps are retractions. As a corollary, we show that the class of Valdivia compacta of weight at most $\\aleph_1$ is preserved both under retractions and under open 0-dimensional images. Finally, we characterize the class of all Valdivia compacta in the language of category theory, which implies that this class is preserved under all continuous weight preserving functors.

  15. D-strings in unconventional type I vacuum configurations

    International Nuclear Information System (INIS)

    Bianchi, M.; Gava, E.; Morales, F.; Narain, K.S.

    1998-11-01

    We determine the spectrum of D-string bound states in various classes of generalized type I vacuum configurations with sixteen and eight supercharges. The precise matching of the BPS spectra confirms the duality between unconventional type IIB orientfolds with quantized NS-NS antisymmetric tensor and heterotic CHL models in D=8. A similar analysis puts the duality between type II (4,0) models and type I strings without open strings on a firmer ground. The analysis can be extended to type II (2,0) asymmetric orbifolds and their type I duals that correspond to unconventional K3 compactifications. Finally we discuss BPS-saturated threshold corrections to the corresponding low-energy effective lagrangians. In particular we show how the exact moduli dependence of some F 4 terms in the eight-dimensional type II (4,0) orbifold is reproduced by the infinite sum of D-instanton contributions in the dual type I theory. (author)

  16. THE PROGENITOR OF THE TYPE IIb SN 2008ax REVISITED

    International Nuclear Information System (INIS)

    Folatelli, Gastón; Bersten, Melina C.; Benvenuto, Omar G.; Kuncarayakti, Hanindyo; Maeda, Keiichi; Nomoto, Ken’ichi

    2015-01-01

    Hubble Space Telescope observations of the site of the supernova (SN) SN 2008ax obtained in 2011 and 2013 reveal that the possible progenitor object detected in pre-explosion images was in fact multiple. Four point sources are resolved in the new, higher-resolution images. We identify one of the sources with the fading SN. The other three objects are consistent with single supergiant stars. We conclude that their light contaminated the previously identified progenitor candidate. After subtraction of these stars, the progenitor appears to be significantly fainter and bluer than previously measured. Post-explosion photometry at the SN location indicates that the progenitor object has disappeared. If single, the progenitor is compatible with a supergiant star of B to mid-A spectral type, while a Wolf–Rayet (W-R) star would be too luminous in the ultraviolet to account for the observations. Moreover, our hydrodynamical modeling shows that the pre-explosion mass was 4–5 M ⊙ and the radius was 30–50 R ⊙ , which is incompatible with a W-R progenitor. We present a possible interacting binary progenitor computed with our evolutionary models that reproduces all the observational evidence. A companion star as luminous as an O9–B0 main-sequence star may have remained after the explosion

  17. Compaction comparison testing using a modified impact soil tester and nuclear density gauge

    Energy Technology Data Exchange (ETDEWEB)

    Erchul, R.A.

    1999-07-01

    The purpose of this paper is to compare test results of a modified Impact Soil Tester (IST) on compacted soil with data obtained from the same soil using a nuclear density gauge at the US Army Corp of Engineer's Buena Vista Flood Wall project in Buena Vista, Virginia. The tests were run during construction of the earth flood wall during the summer of 1996. This comparison testing demonstrated the credibility of the procedure developed for the IST as a compacting testing device. The comparison data was obtained on a variety of soils ranging from silty sands to clays. The Flood Wall comparison compaction data for 90% Standard Proctor shows that the results of the IST as modified are consistent with the nuclear density gauge 89% of the time for all types of soil tested. However, if the soils are more cohesive than the results are consistent with the nuclear density gauge 97% of the time. In addition these comparison tests are in general agreement with comparison compaction testing using the same testing techniques and methods of compacted backfill in utility trenches conducted earlier for the Public Works Department, Chesterfield County, Virginia.

  18. Compaction comparison testing using a modified impact soil tester and nuclear density gauge

    International Nuclear Information System (INIS)

    Erchul, R.A.

    1999-01-01

    The purpose of this paper is to compare test results of a modified Impact Soil Tester (IST) on compacted soil with data obtained from the same soil using a nuclear density gauge at the US Army Corp of Engineer's Buena Vista Flood Wall project in Buena Vista, Virginia. The tests were run during construction of the earth flood wall during the summer of 1996. This comparison testing demonstrated the credibility of the procedure developed for the IST as a compacting testing device. The comparison data was obtained on a variety of soils ranging from silty sands to clays. The Flood Wall comparison compaction data for 90% Standard Proctor shows that the results of the IST as modified are consistent with the nuclear density gauge 89% of the time for all types of soil tested. However, if the soils are more cohesive than the results are consistent with the nuclear density gauge 97% of the time. In addition these comparison tests are in general agreement with comparison compaction testing using the same testing techniques and methods of compacted backfill in utility trenches conducted earlier for the Public Works Department, Chesterfield County, Virginia

  19. Clustering of near clusters versus cluster compactness

    International Nuclear Information System (INIS)

    Yu Gao; Yipeng Jing

    1989-01-01

    The clustering properties of near Zwicky clusters are studied by using the two-point angular correlation function. The angular correlation functions for compact and medium compact clusters, for open clusters, and for all near Zwicky clusters are estimated. The results show much stronger clustering for compact and medium compact clusters than for open clusters, and that open clusters have nearly the same clustering strength as galaxies. A detailed study of the compactness-dependence of correlation function strength is worth investigating. (author)

  20. Response Of Lowland Rice To Soil Compaction

    International Nuclear Information System (INIS)

    Idawati; Haryanto

    2000-01-01

    Soil compaction, as a new tillage practice for paddy soil, is to substitute pudding in order to reduce land preparation cost. To study response of lowland rice to soil compaction, a pot experiment has been conducted which took place in the greenhouse of P3TIR-BATAN. Soil for experiment was taken from pusakanegara. Two factors (degree of soil compaction and rice variety) were combined. Degree of compaction was split into 3 levels (DI = normal; D215% more compact than normal; 30 % more compact than normal), and rice variety into 2 levels (IR64 and Atomita IV). KH 2 32 PO 4 solution was injected into the soil surrounding rice clump to test the root activity at blooming stage of rice plant. Data resulted from this experiment is presented together with additional data from some other experiments of fertilization in the research s erie to study soil compaction. Some information's from experiment results are as following. Both rice varieties tested gave the same response to soil compaction. Root activity, according to data of 32 P absorbed by plant, was not harmed by soil compaction at the degree tested in the experiment. This prediction is supported by the growth by rice observed at generative growth stage, in pot experiment as well as in field experiment, which showed that soil compaction tested did not decrease rice yield but in opposite in tended to increase the yield. In practising soil compaction in land preparation, fertilizers should be applied by deep placement to have higher increasing is rice yield

  1. Formation and evolution of compact binaries

    NARCIS (Netherlands)

    Sluijs, Marcel Vincent van der

    2006-01-01

    In this thesis we investigate the formation and evolution of compact binaries. Chapters 2 through 4 deal with the formation of luminous, ultra-compact X-ray binaries in globular clusters. We show that the proposed scenario of magnetic capture produces too few ultra-compact X-ray binaries to explain

  2. Monitoring of homogeneity of fuel compacts for high-temperature reactors

    International Nuclear Information System (INIS)

    Mottet, P.; Guery, M.; Chegne, J.

    Apparatus using either gamma transmission or gamma scintillation spectrometry (with NaI(Tl) detector) was developed for monitoring the homogeneity of distribution of fissile and fertile particles in fuel compacts for high-temperature reactors. Three methods were studied: Longitudinal gamma transmission which gives a total distribution curve of heavy metals (U and Th); gamma spectrometry with a well type scintillator, which rapidly gives the U and Th count rates per fraction of compact; and longitudinal gamma spectrometry, giving axial distribution curves for uranium and thorium; apparatus with four scintillators and optimization of the parameters for the measurement, permitting significantly decreasing the duration of the monitoring. These relatively simple procedures should facilitate the industrial monitoring of high-temperature reactor fuel

  3. Iterative solution of high order compact systems

    Energy Technology Data Exchange (ETDEWEB)

    Spotz, W.F.; Carey, G.F. [Univ. of Texas, Austin, TX (United States)

    1996-12-31

    We have recently developed a class of finite difference methods which provide higher accuracy and greater stability than standard central or upwind difference methods, but still reside on a compact patch of grid cells. In the present study we investigate the performance of several gradient-type iterative methods for solving the associated sparse systems. Both serial and parallel performance studies have been made. Representative examples are taken from elliptic PDE`s for diffusion, convection-diffusion, and viscous flow applications.

  4. Inverse modeling of geochemical and mechanical compaction in sedimentary basins

    Science.gov (United States)

    Colombo, Ivo; Porta, Giovanni Michele; Guadagnini, Alberto

    2015-04-01

    We study key phenomena driving the feedback between sediment compaction processes and fluid flow in stratified sedimentary basins formed through lithification of sand and clay sediments after deposition. Processes we consider are mechanic compaction of the host rock and the geochemical compaction due to quartz cementation in sandstones. Key objectives of our study include (i) the quantification of the influence of the uncertainty of the model input parameters on the model output and (ii) the application of an inverse modeling technique to field scale data. Proper accounting of the feedback between sediment compaction processes and fluid flow in the subsurface is key to quantify a wide set of environmentally and industrially relevant phenomena. These include, e.g., compaction-driven brine and/or saltwater flow at deep locations and its influence on (a) tracer concentrations observed in shallow sediments, (b) build up of fluid overpressure, (c) hydrocarbon generation and migration, (d) subsidence due to groundwater and/or hydrocarbons withdrawal, and (e) formation of ore deposits. Main processes driving the diagenesis of sediments after deposition are mechanical compaction due to overburden and precipitation/dissolution associated with reactive transport. The natural evolution of sedimentary basins is characterized by geological time scales, thus preventing direct and exhaustive measurement of the system dynamical changes. The outputs of compaction models are plagued by uncertainty because of the incomplete knowledge of the models and parameters governing diagenesis. Development of robust methodologies for inverse modeling and parameter estimation under uncertainty is therefore crucial to the quantification of natural compaction phenomena. We employ a numerical methodology based on three building blocks: (i) space-time discretization of the compaction process; (ii) representation of target output variables through a Polynomial Chaos Expansion (PCE); and (iii) model

  5. Type II pp-wave matrix models from point-like gravitons

    International Nuclear Information System (INIS)

    Lozano, Yolanda; RodrIguez-Gomez, Diego

    2006-01-01

    The BMN Matrix model can be regarded as a theory of coincident M-theory gravitons, which expand by Myers dielectric effect into the 2-sphere and 5-sphere giant graviton vacua of the theory. In this note we show that, in the same fashion, Matrix String theory in Type IIA pp-wave backgrounds arises from the action for coincident Type IIA gravitons. In Type IIB, we show that the action for coincident gravitons in the maximally supersymmetric pp-wave background gives rise to a Matrix model which supports fuzzy 3-sphere giant graviton vacua with the right behavior in the classical limit. We discuss the relation between our Matrix model and the Tiny Graviton Matrix theory

  6. Specific Molecular Signatures for Type II Crustins in Penaeid Shrimp Uncovered by the Identification of Crustin-Like Antimicrobial Peptides in Litopenaeus vannamei

    Science.gov (United States)

    Barreto, Cairé; Coelho, Jaqueline da Rosa; Yuan, Jianbo; Xiang, Jianhai; Perazzolo, Luciane Maria

    2018-01-01

    Crustins form a large family of antimicrobial peptides (AMPs) in crustaceans composed of four sub-groups (Types I-IV). Type II crustins (Type IIa or “Crustins” and Type IIb or “Crustin-like”) possess a typical hydrophobic N-terminal region and are by far the most representative sub-group found in penaeid shrimp. To gain insight into the molecular diversity of Type II crustins in penaeids, we identified and characterized a Type IIb crustin in Litopenaeus vannamei (Crustin-like Lv) and compared Type II crustins at both molecular and transcriptional levels. Although L. vannamei Type II crustins (Crustin Lv and Crustin-like Lv) are encoded by separate genes, they showed a similar tissue distribution (hemocytes and gills) and transcriptional response to the shrimp pathogens Vibrio harveyi and White spot syndrome virus (WSSV). As Crustin Lv, Crustin-like Lv transcripts were found to be present early in development, suggesting a maternal contribution to shrimp progeny. Altogether, our in silico and transcriptional data allowed to conclude that (1) each sub-type displays a specific amino acid signature at the C-terminal end holding both the cysteine-rich region and the whey acidic protein (WAP) domain, and that (2) shrimp Type II crustins evolved from a common ancestral gene that conserved a similar pattern of transcriptional regulation. PMID:29337853

  7. Study of the core compaction effects and its monitoring in sodium cooled fast reactors

    International Nuclear Information System (INIS)

    Zylbersztejn, F.

    2012-01-01

    Conclusions: • On calculation of reactivity impacts of core compaction/flowering: → Upper bound of the reactivity coefficients for each type of deformation; → Uniform compaction model: significant reactivity impact; Circular symmetric model: small reactivity impact. • On the visibility of these phenomena by the neutron detectors: → The direct monitoring of the core compaction by neutron detector in the BCC is not possible. (the identification that the reactivity perturbations observed are due to variation of the core geometry). Perspectives of solutions: → Improved core design: reducing the effects. → Physical improvements: Steel resistance to deformations (irradiation, flexion); Direct devices: core constraint (prevents deformations). → Additional calculations: Considering more localized deformations; Advanced monitoring with neutron noise (in progress)

  8. The Type IIb Supernova 2013df and its Cool Supergiant Progenitor

    Science.gov (United States)

    VanDyk, Schuyler D.; Zeng, Weikang; Fox, Ori D.; Cenko, S. Bradley; Clubb, Kelsey I.; Filippenko, Alexei; Foley, Ryan J.; Miller, Adam A.; Smith, Nathan; Kelly, Patrick L.; hide

    2014-01-01

    We have obtained early-time photometry and spectroscopy of supernova (SN) 2013df in NGC 4414. The SN is clearly of Type II b, with notable similarities to SN 1993J. From its luminosity at secondary maximum light, it appears that less Ni-56 (is approximately less than 0.06M) was synthesized in the SN 2013df explosion than was the case for the SNe II b 1993J, 2008ax, and 2011dh. Based on a comparison of the light curves, the SN 2013df progenitor must have been more extended in radius prior to explosion than the progenitor of SN 1993J. The total extinction for SN 2013dfis estimated to be A(sub V) = 0.30 mag. The metallicity at the SN location is likely to be solar. We have conducted Hubble Space Telescope(HST) Target of Opportunity observations of the SN with the Wide Field Camera 3, and from a precise comparison of these new observations to archival HST observations of the host galaxy obtained 14 yr prior to explosion, we have identified the progenitor of SN 2013df to be a yellow supergiant, somewhat hotter than a red supergiant progenitor for a normal Type II-Plateau SN. From its observed spectral energy distribution, assuming that the light is dominated by one star, the progenitor had effective temperature T(sub eff) = 4250+/-100 K and a bolometric luminosity L(sub bol) =10(exp 4.94+/-0.06) Solar Luminosity. This leads to an effective radius Reff = 545+/-65 Solar Radius. The star likely had an initial mass in the range of 13-17Solar Mass; however, if it was a member of an interacting binary system, detailed modeling of the system is required to estimate this mass more accurately. The progenitor star of SN 2013df appears to have been relatively similar to the progenitor of SN 1993J.

  9. Design study of electrostatic inflector in compact cyclotron injection system

    International Nuclear Information System (INIS)

    Zhang Tianjue; Fan Mingwu

    1996-01-01

    The beam dynamics behaviour in electrostatic inflector is investigated for a vertical type injection system to a compact cyclotron. The computer aided design and matching of the inflector are based on the simulation of computed beam orbit. Modeling and simulation are done on PC-486 to form a software package. The software package can be used to develop a new type cyclotron design combining with the software package CYCCAE developed by China Institute of Atomic Energy three years ago

  10. Equationally Compact Acts : Coproducts / Peeter Normak

    Index Scriptorium Estoniae

    Normak, Peeter

    1998-01-01

    In this article equational compactness of acts and its generalizations are discussed. As equational compactness does not carry over to coproducts a slight generalization of c-equational campactness is introduced. It is proved that a coproduct of acts is c-equationally compact if and only if all components are c-equationally campact

  11. THE PROGENITOR OF THE TYPE IIb SN 2008ax REVISITED

    Energy Technology Data Exchange (ETDEWEB)

    Folatelli, Gastón; Bersten, Melina C.; Benvenuto, Omar G. [Instituto de Astrofísica de La Plata (Argentina); Kuncarayakti, Hanindyo [Millennium Institute of Astrophysics (MAS), Casilla 36-D, Santiago (Chile); Maeda, Keiichi; Nomoto, Ken’ichi, E-mail: gaston@fcaglp.unlp.edu.ar [Kavli Institute for the Physics and Mathematics of the Universe (WPI), The University of Tokyo, Kashiwa, Chiba 277-8583 (Japan)

    2015-10-01

    Hubble Space Telescope observations of the site of the supernova (SN) SN 2008ax obtained in 2011 and 2013 reveal that the possible progenitor object detected in pre-explosion images was in fact multiple. Four point sources are resolved in the new, higher-resolution images. We identify one of the sources with the fading SN. The other three objects are consistent with single supergiant stars. We conclude that their light contaminated the previously identified progenitor candidate. After subtraction of these stars, the progenitor appears to be significantly fainter and bluer than previously measured. Post-explosion photometry at the SN location indicates that the progenitor object has disappeared. If single, the progenitor is compatible with a supergiant star of B to mid-A spectral type, while a Wolf–Rayet (W-R) star would be too luminous in the ultraviolet to account for the observations. Moreover, our hydrodynamical modeling shows that the pre-explosion mass was 4–5 M{sub ⊙} and the radius was 30–50 R{sub ⊙}, which is incompatible with a W-R progenitor. We present a possible interacting binary progenitor computed with our evolutionary models that reproduces all the observational evidence. A companion star as luminous as an O9–B0 main-sequence star may have remained after the explosion.

  12. The United Nations Global Compact

    DEFF Research Database (Denmark)

    Rasche, Andreas; Waddock, Sandra; McIntosh, Malcolm

    2013-01-01

    This article reviews the interdisciplinary literature on the UN Global Compact. The review identifies three research perspectives, which scholars have used to study the UN Global Compact so far: a historical perspective discussing the Global Compact in the context of UN-business relations...... key empirical as well as conceptual scholarly contributions. The remainder of this article contains focused summaries of the articles selected for this Special Issue. All articles are introduced and evaluated against the background of the three research perspectives....

  13. Effects of Density and Moisture Variation on Dynamic Deformation Properties of Compacted Lateritic Soil

    Directory of Open Access Journals (Sweden)

    Weizheng Liu

    2016-01-01

    Full Text Available A series of repeated load triaxial tests were conducted in this study to investigate the influences of compaction density and postcompaction moisture variation on the dynamic elastic modulus (Ed and plastic permanent strain (PPS of compacted lateritic soil. Specimens were compacted at optimum moisture content (OMC and three degrees of compaction (90%, 93%, and 96%. Then the specimens were dried or wetted to different moisture contents (OMC, OMC±3%, OMC±6%, and OMC+9% prior to testing for Ed and PPS. Results show that moisture content has greater influence on the Ed and PSS than compaction degree, and the increase in moisture content leads to a decrease of Ed and an increase of PPS. Furthermore, an empirical relationship between Ed and applied cyclic stress (σd is developed that incorporates density and moisture variations. Three different evolution types of PPS with number of load cycles, plastic stable, plastic creep, and incremental collapse, are identified as the increase of moisture content. In addition, the critical dynamic stress (σdc separating stable and unstable deformation is determined based on the shakedown concept. The envelope curves of σdc-moisture of lateritic soil with different degrees of compaction are also determined to provide reference for the pavement design.

  14. Compaction of spent nuclear fuel cans

    International Nuclear Information System (INIS)

    Sullivan, H.

    1985-01-01

    Hydraulic press apparatus for compacting waste material eg. spent nuclear fuel cans comprises a fixed frame, a movable cross head, a press crown and three groups of piston/cylinder devices; having their pistons connected to the cross head and their cylinders secured to the press crown. A control means connects the first group of devices to hydraulic fluid in a reservoir which is pressurised initially by gas from gas accumulators to move the cross head and a quill secured thereto towards the frame base to compact the waste at a first high rate under a first high loading. Compaction then proceeds at a lower second rate at a lower second loading as the hydraulic fluid in the reservoir is pressurised by a pump. At two subsequent stages of compaction of the waste at which resistance increases causing a pressure rise in cylinders the control means causes hydraulic fluid to be passed to the second group of devices and thence to the third group of devices, the compaction rate reducing at each stage but the compaction force increasing. (author)

  15. F-theory uplifts and GUTs

    International Nuclear Information System (INIS)

    Blumenhagen, Ralph; Jurke, Benjamin; Grimm, Thomas W.; Weigand, Timo

    2009-01-01

    We study the F-theory uplift of Type IIB orientifold models on compact Calabi-Yau threefolds containing divisors which are del Pezzo surfaces. We consider two examples defined via del Pezzo transitions of the quintic. The first model has an orientifold projection leading to two disjoint O7-planes and the second involution acts via an exchange of two del Pezzo surfaces. The two uplifted fourfolds are generically singular with minimal gauge enhancements over a divisor and, respectively, a curve in the non-Fano base. We study possible further degenerations of the elliptic fiber leading to F-theory GUT models based on subgroups of E 8 .

  16. Physically detached 'compact groups'

    Science.gov (United States)

    Hernquist, Lars; Katz, Neal; Weinberg, David H.

    1995-01-01

    A small fraction of galaxies appear to reside in dense compact groups, whose inferred crossing times are much shorter than a Hubble time. These short crossing times have led to considerable disagreement among researchers attempting to deduce the dynamical state of these systems. In this paper, we suggest that many of the observed groups are not physically bound but are chance projections of galaxies well separated along the line of sight. Unlike earlier similar proposals, ours does not require that the galaxies in the compact group be members of a more diffuse, but physically bound entity. The probability of physically separated galaxies projecting into an apparent compact group is nonnegligible if most galaxies are distributed in thin filaments. We illustrate this general point with a specific example: a simulation of a cold dark matter universe, in which hydrodynamic effects are included to identify galaxies. The simulated galaxy distribution is filamentary and end-on views of these filaments produce apparent galaxy associations that have sizes and velocity dispersions similar to those of observed compact groups. The frequency of such projections is sufficient, in principle, to explain the observed space density of groups in the Hickson catalog. We discuss the implications of our proposal for the formation and evolution of groups and elliptical galaxies. The proposal can be tested by using redshift-independent distance estimators to measure the line-of-sight spatial extent of nearby compact groups.

  17. Permeability, porosity and compressive strength of self-compacting concrete

    Directory of Open Access Journals (Sweden)

    Valcuende, M.O.

    2005-12-01

    Full Text Available Most deterioration affecting the durability of self-compacting concrete structures is mediated by water penetration in the concrete, a condition related to its porous structure. The present study analyzes these two factors. To this end, two types of concrete were prepared, a self-compacting and a traditional vibrated concrete, with different W/C ratios and different types of cement. The results of low-pressure water testing to evaluate permeability and analyses to determine compressive strength and pore size distribution showed that self-compacting concrete has lower capillary porosity than traditional concrete, which would explain its greater resistance to water penetration. Such concrete likewise reached higher strength values, except where large proportions of lime powder with low sand equivalents were used in its manufacture, when lower strength was recorded. Lastly, the depth of water penetration and compressive strength were found to be linearly correlated. That correlation was seen to depend, in turn, on the type of concrete, since for any given strength level, self-compacting concrete was less permeable than the traditional material.

    En este trabajo experimental se estudia la penetración de agua en hormigones autocompactables, analizando al mismo tiempo su estructura porosa, pues gran parte de los procesos de deterioro que afectan a la durabilidad de las estructuras están condicionados por estos dos aspectos. Para ello se han fabricado dos tipos de hormigones, uno autocompactable y otro tradicional vibrado, con diferentes relaciones A/C y distintos tipos de cemento. Tras determinar la permeabilidad al agua bajo presión, la resistencia a compresión y las distribuciones de tamaño de poro, los resultados obtenidos ponen de manifiesto que los hormigones autocompactables presentan menor porosidad capilar que los tradicionales, lo que les confiere mejores prestaciones frente a la penetración de agua. Asimismo, dichos hormigones

  18. Peculiarities of powder brittle media compaction

    International Nuclear Information System (INIS)

    Perel'nam, V.E.; Aristarkhov, A.I.

    1981-01-01

    The paper is concerned with theoretical and practical aspects of the compaction process for powders of almost unstrained materials. Consideration from the standpoint of compressible body strain mechanics shows that such porous media may have a certain ''threshold'' density. Ductile characteristics of the porous material compacted up to this extent are identical with properties of compacrat bodies, i.e. there is a theoretically substantiated ban on a possibility of their further compaction without changing the state of the powder particle material. Theoretical conclusions are confirmed by results of experimental studies in compaction of titanium- containing ceramics [ru

  19. Measurements on irradiated L1 sensor prototypes for the D0 Run IIb silicon detector project

    International Nuclear Information System (INIS)

    Ahsan, M.; Bolton, T.; Carnes, K.; Demarteau, M.; Demina, R.; Gray, T.; Korjenevski, S.; Lehner, F.; Lipton, R.; Mao, H.S.; McCarthy, R.

    2010-01-01

    We report on irradiation studies of Hamamatsu prototype silicon microstrip detectors for layer 1 of the D0 upgrade project for Run IIb. The irradiation was carried out with 10 MeV protons up to proton fluence of 10 14 p/cm 2 at the J.R. Macdonald Laboratory, Manhatten, KS. The flux calibration was carefully checked using different dose normalization techniques. The results based on the obtained sensor leakage currents after irradiation show that the NIEL scaling hypothesis for low energy protons has to be applied with great care. We observe 30-40% less radiation damage in silicon for 10 MeV proton exposure than is expected from the predicted NIEL scaling.

  20. Measurements on irradiated L1 sensor prototypes for the D0 Run IIb silicon detector project

    Energy Technology Data Exchange (ETDEWEB)

    Ahsan, M.; Bolton, T.; Carnes, K.; /Kansas State U.; Demarteau, M.; /Fermilab; Demina, R.; /Rochester U.; Gray, T.; /Kansas State U.; Korjenevski, S.; /Rochester U.; Lehner, F.; /Zurich U.; Lipton, R.; Mao, H.S.; /Fermilab; McCarthy, R.; /SUNY, Stony Brook /Kansas State U. /Fermilab

    2010-01-01

    We report on irradiation studies of Hamamatsu prototype silicon microstrip detectors for layer 1 of the D0 upgrade project for Run IIb. The irradiation was carried out with 10 MeV protons up to proton fluence of 10{sup 14} p/cm{sup 2} at the J.R. Macdonald Laboratory, Manhatten, KS. The flux calibration was carefully checked using different dose normalization techniques. The results based on the obtained sensor leakage currents after irradiation show that the NIEL scaling hypothesis for low energy protons has to be applied with great care. We observe 30-40% less radiation damage in silicon for 10 MeV proton exposure than is expected from the predicted NIEL scaling.

  1. EPRI compact analyzer: A compact, interactive and color-graphics based simulator for power plant analysis

    International Nuclear Information System (INIS)

    Ipakchi, A.; Khadem, M.; Chen, H.; Colley, R.W.

    1986-01-01

    This paper presents the results of an EPRI sponsored project (RP2395-2) for design and development of an interactive, and color graphics based simulator for power plant analysis. The system is called Compact Analyzer and can be applied to engineering and training applications in the utility industry. The Compact Analyzer's software and system design are described. Results of two demonstration system for a nuclear plant, and a fossil plant are presented, and the applications of the Compact Analyzer to operating procedures evaluation are discussed

  2. The Future Concrete: Self-Compacting Concrete

    OpenAIRE

    Iureş, Liana; Bob, Corneliu

    2010-01-01

    The paper presents the characteristics of the self-compacting concretes, their advantages and disadvantages when they are used in buildings. Due to its properties and composition, the self-compacting concrete is described here as being one of the future friendly enviromental material for buildings. Tests concerning to obtaining a self-compacting concrete, together with the specific fresh concrete properties tests, are described.

  3. Powder compaction in systems of bimodal distribution

    Science.gov (United States)

    Chattopadhyay, A. K.; Whittemore, O. J., Jr.

    1973-01-01

    The compaction of mixtures involving different particle sizes is discussed. The various stages of the compaction process include the rearrangement of particles, the filling of the interstices of the large particles by the smaller ones, and the change in particle size and shape upon further densification through the application of pressure. Experimental approaches and equipment used for compacting material are discussed together with the theoretical relations of the compacting process.

  4. PGC-1α mRNA Level and Oxidative Capacity of the Plantaris Muscle in Rats with Metabolic Syndrome, Hypertension, and Type 2 Diabetes

    International Nuclear Information System (INIS)

    Nagatomo, Fumiko; Fujino, Hidemi; Kondo, Hiroyo; Gu, Ning; Takeda, Isao; Ishioka, Noriaki; Tsuda, Kinsuke; Ishihara, Akihiko

    2011-01-01

    We examined the fiber profiles and the mRNA levels of peroxisome proliferator-activated receptors (PPARα and PPARδ/β) and of the PPARγ coactivator-1α (PGC-1α) in the plantaris muscles of 15-week-old control (WR), metabolic syndrome (CP), hypertensive (SHR), and type 2 diabetic (GK) rats. The deep regions in the muscles of SHR and GK rats exhibited lower percentages of high-oxidative type I and IIA fibers and higher percentages of low-oxidative type IIB fibers compared with WR and CP rats. The surface regions in the muscles of CP, SHR, and GK rats exhibited lower percentages of high-oxidative type IIA fibers and higher percentages of low-oxidative type IIB fibers compared with WR rats. The muscles of SHR and GK rats had lower oxidative enzyme activity compared with WR rats. The muscles of SHR rats had the lowest PPARδ/β mRNA level. In addition, the muscles of SHR and GK rats had lower PGC-1α mRNA level compared with WR and CP rats. We concluded that the plantaris muscles of rats with hypertension and type 2 diabetes have lower oxidative capacity, which is associated with the decreased level of PGC-1α mRNA

  5. Systems Analysis of a Compact Next Step Burning Plasma Experiment

    International Nuclear Information System (INIS)

    Jardin, S.C.; Kessel, C.E.; Meade, D.; Neumeyer, C.

    2002-01-01

    A new burning plasma systems code (BPSC) has been developed for analysis of a next step compact burning plasma experiment with copper-alloy magnet technology. We consider two classes of configurations: Type A, with the toroidal field (TF) coils and ohmic heating (OH) coils unlinked, and Type B, with the TF and OH coils linked. We obtain curves of the minimizing major radius as a function of aspect ratio R(A) for each configuration type for typical parameters. These curves represent, to first order, cost minimizing curves, assuming that device cost is a function of major radius. The Type B curves always lie below the Type A curves for the same physics parameters, indicating that they lead to a more compact design. This follows from that fact that a high fraction of the inner region, r < R-a, contains electrical conductor material. However, the fact that the Type A OH and TF magnets are not linked presents fewer engineering challenges and should lead to a more reliable design. Both the Type A and Type B curves have a minimum in major radius R at a minimizing aspect ratio A typically above 2.8 and at high values of magnetic field B above 10 T. The minimizing A occurs at larger values for longer pulse and higher performance devices. The larger A and higher B design points also have the feature that the ratio of the discharge time to the current redistribution time is largest so that steady-state operation can be more realistically prototyped. A sensitivity study is presented for the baseline Type A configuration showing the dependence of the results on the parameters held fixed for the minimization study

  6. Compact vortices

    Energy Technology Data Exchange (ETDEWEB)

    Bazeia, D.; Losano, L.; Marques, M.A.; Zafalan, I. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil); Menezes, R. [Universidade Federal da Paraiba, Departamento de Ciencias Exatas, Rio Tinto, PB (Brazil); Universidade Federal de Campina Grande, Departamento de Fisica, Campina Grande, PB (Brazil)

    2017-02-15

    We study a family of Maxwell-Higgs models, described by the inclusion of a function of the scalar field that represent generalized magnetic permeability. We search for vortex configurations which obey first-order differential equations that solve the equations of motion. We first deal with the asymptotic behavior of the field configurations, and then implement a numerical study of the solutions, the energy density and the magnetic field. We work with the generalized permeability having distinct profiles, giving rise to new models, and we investigate how the vortices behave, compared with the solutions of the corresponding standard models. In particular, we show how to build compact vortices, that is, vortex solutions with the energy density and magnetic field vanishing outside a compact region of the plane. (orig.)

  7. Compaction monitoring in the Ekofisk area Chalk Fields

    International Nuclear Information System (INIS)

    Menghini, M.L.

    1989-01-01

    In late Nov. 1984, the subsidence phenomenon was recognized in the Ekofisk field. To determine the magnitude and areal extent of the formation compaction, a program for measuring compaction with electric logging tools was initiated. Initial time-lapse surveys performed with cased-hole neutron tools indicated that reservoir compaction was occurring, but the accuracy of the determination of compaction rate was low. In addition to the cased-hole neutron survey, radioactive markers and a gamma ray (GR) detection tool were used to determine compaction rate in the reservoir more accurately and to determine whether compaction was occurring in the overburden. A program for implanting radioactive-marker bullets and subsequent monitoring with a four-detector GR tool was implemented. There are currently 13 wells equipped with radioactive markers in the compaction monitoring program. Compaction monitoring accuracy using the four-detector GR tool was found to depend on wellbore geometry, completion design, and radioactive-marker placement. This paper gives the results of the program to date and describes the operational procedures and analysis techniques used for compaction monitoring in the greater Ekofisk area chalk fields

  8. ANALISIS PENENTUAN HARGA POKOK PRODUKSI DENGAN MENGGUNAKAN METODE TIME DRIVEN ACTIVITY BASED COSTING (TDABC PADA PT IIB

    Directory of Open Access Journals (Sweden)

    Arfan Bakhtiar

    2017-01-01

      PT IIB is a manufacturing companywith major product Carton box packaging and Pulp Tray and Pallet as side products. This products using materials cardboard, scrap paper and wood. Company using calculations with adding material costs, employees’ salary costs in each activity and% profit. The bigsize product need large space, demanding supply system of Just In Time (JIT, is timely in production only to order, if there is an additional need to do overtime. So it takes time calculation standard that can be estimated lead time. So, need a method to determine an accurate cost to unify the cost of each activity, support costs and standard time. The method used is the Time-Driven Activity Based Costing (TDABC. TDABC is a method of formulating the charges on the basis of time, all of the resources used in the production are converted into units of time. The results of this research to acquire all of the costs related to production processes and support costs, gain time standard that is necessary to make three types of products and obtain a calculation of the cost of production for Box RSC Rp 4.006,-, Box DC Rp 4.449,-, Pulp Tray Rp 350,- and Pallet Kayu Rp 155.902,-,and obtain comparative results of the calculation TDABC method and company.

  9. Does soil compaction increase floods? A review

    Science.gov (United States)

    Alaoui, Abdallah; Rogger, Magdalena; Peth, Stephan; Blöschl, Günter

    2018-02-01

    Europe has experienced a series of major floods in the past years which suggests that flood magnitudes may have increased. Land degradation due to soil compaction from crop farming or grazing intensification is one of the potential drivers of this increase. A literature review suggests that most of the experimental evidence was generated at plot and hillslope scales. At larger scales, most studies are based on models. There are three ways in which soil compaction affects floods at the catchment scale: (i) through an increase in the area affected by soil compaction; (ii) by exacerbating the effects of changes in rainfall, especially for highly degraded soils; and (iii) when soil compaction coincides with soils characterized by a fine texture and a low infiltration capacity. We suggest that future research should focus on better synthesising past research on soil compaction and runoff, tailored field experiments to obtain a mechanistic understanding of the coupled mechanical and hydraulic processes, new mapping methods of soil compaction that combine mechanical and remote sensing approaches, and an effort to bridge all disciplines relevant to soil compaction effects on floods.

  10. D-brane superpotentials and Ooguri-Vafa invariants of compact Calabi-Yau threefolds

    Science.gov (United States)

    Xu, Feng-Jun; Yang, Fu-Zhong

    2015-04-01

    We calculate the D-brane superpotentials for two compact Calabi-Yau manifolds X14(1,1,2,3,7) and X8(1,1,1,2,3) which are of non-Fermat type in the type II string theory. By constructing the open mirror symmetry, we also compute the Ooguri-Vafa invariants, which are related to the open Gromov-Witten invariants. Supported by NSFC (11075204, 11475178)

  11. Application of dynamic compaction technology for high performance and precision powder products

    International Nuclear Information System (INIS)

    Lee, Chang Kyu; Lee, Jung Gu; Lee, Min Ku; Uhm, Young Rang; Park, Jin Ju; Lee, Gyeong Ja; Hong, Soon Jik

    2011-06-01

    The automation technology of magnetic pulsed compaction (MPC) has been developed for mass production of high performance powder products by dynamic compaction method. The pulse power equipment in MPC system has been modified for improved lifetime and productivity, so the modified one can produce high-density compacts at a rate of 10 times/min with semipermanent lifetime. Using this modified pulse power equipment, two types of automated MPC apparatus were constructed, which are operated by mechanical and hydraulic driving systems, respectively. By repeated compaction operations at a rate of 5 times/min, durability and productivity of these automated apparatus have been proven to be suitable for mass production. In addition, the lifetime of mold and punch for MPC has been improved by optimizing design and material as well as employing new lubrication system. By applying such automated MPC apparatus, detailed mass production technologies have been developed for several powder products such as diamond drilling segments, ceramic targets for optical coating, silver coins for water disinfection and small powder products for automobile. The developed powder products showed improved performance as compared to commercial ones, so they will be mass-produced industrially before long

  12. Compaction of bentonite blocks. Development of technique for industrial production of blocks which are manageable by man

    Energy Technology Data Exchange (ETDEWEB)

    Johannesson, L E; Boergesson, L; Sanden, T [Clay Technology AB, Lund (Sweden)

    1995-04-01

    In this report a useful technique for producing compacted blocks of bentonite is described. The report only deals with the technique to produce uniaxially compacted blocks (weight of the blocks: 10-15 kg) which are manageable by man. Tests for producing blocks with a weight of approximately 10 kg were carried out at Hoeganaes Bjuf AB in Bjuf. This industry is normally producing refractory bricks and other refractory products. The plant has facilities for handling large volumes of clay. Furthermore there are machines suitable for producing uniaxially compacted blocks. Performed tests at the plant show that it is possible to compact blocks with good quality. Best quality was reached with a coarsely ground bentonite at a water ratio of 20 %. The compaction was performed with lubricated form and stepwise loading. The tests at Hoeganaes Bjuf AB were preceded by tests in the laboratory. In these tests smaller samples were compacted for studying how different factors affect the quality of the samples (density, water ratio, homogeneity et cetera). The influence of following factors was studied: water ratio of bentonite; bentonite type and granulometry; compaction pressure; compaction rate; form geometry; form lubrication; form heating. The results from these tests were used to modify and optimize the technique in the factory.

  13. The Future Concrete: Self-Compacting Concrete

    Directory of Open Access Journals (Sweden)

    Liana Iureş

    2010-01-01

    Full Text Available The paper presents the characteristics of the self-compacting concretes, their advantages and disadvantages when they are used in buildings. Due to its properties and composition, the self-compacting concrete is described here as being one of the future friendly enviromental material for buildings. Tests concerning to obtaining a self-compacting concrete, together with the specific fresh concrete properties tests, are described.

  14. Prediction for swelling characteristics of compacted bentonite

    International Nuclear Information System (INIS)

    Komine, H.; Ogata, N.

    1996-01-01

    Compacted bentonites are attracting greater attention as back-filling (buffer) materials for high-level nuclear waste repositories. For this purpose, it is very important to quantitatively evaluate the swelling characteristics of compacted bentonite. New equations for evaluating the relationship between the swelling deformation of compacted bentonite and the distance between two montmorillonite layers are derived. New equations for evaluating the ion concentration of pore water and the specific surface of bentonite, which significantly influence the swelling characteristics of compacted bentonite, are proposed. Furthermore, a prediction method for the swelling characteristics of compacted bentonite is presented by combining the new equations with the well-known theoretical equations of repulsive and attractive forces between two montmorillonite layers. The applicability of this method was investigated by comparing the predicted results with laboratory test results on the swelling deformation and swelling pressure of compacted bentonites. (author) 31 refs., 8 tabs., 12 figs

  15. Schwinger type processes via branes and their gravity duals

    International Nuclear Information System (INIS)

    Gorsky, A.S.; Saraikin, K.A.; Selivanov, K.G.

    2002-01-01

    We consider Schwinger type processes involving the creation of the charge and monopole pairs in the external fields and propose interpretation of these processes via corresponding brane configurations in type IIB string theory. We suggest simple description of some new interesting nonperturbative processes like monopole/dyon transitions in the electric field and W-boson decay in the magnetic field using the brane language. Nonperturbative pair production in the strong coupling regime using the AdS/CFT correspondence is studied. The treatment of the similar processes in the noncommutative theories when noncommutativity is traded for the background fields is presented and the possible role of the critical magnetic field which is S-dual to the critical electric field is discussed

  16. Composition and cross-sectional area of muscle fibre types in relation to daily gain and lean and fat content of carcass in Landrace and Yorkshire pigs

    Directory of Open Access Journals (Sweden)

    M. RUUSUNEN

    2008-12-01

    Full Text Available The muscle fibre-type properties of longissimus were compared between Landrace and Yorkshire breeds and between the sexes in an attempt to shed light on the relationship of these histochemical parameters to animal growth and carcass composition. Muscle fibres were classified into three groups, type I, type IIA and type IIB, using the myosin ATPase method. At a given live weight, the cross-sectional area of type I fibres (CSA I was smaller (p

  17. X-Ray Investigation and Strength Measurement of Steel Fibre Reinforced Self-Compacting Concrete Beams

    Directory of Open Access Journals (Sweden)

    Ponikiewski Tomasz

    2016-12-01

    Full Text Available The paper presents a study on self-compacting concrete with two types of steel fibres. Under consideration was the effect the method of forming of beam elements has on the distribution of steel fibres. Formed we beams of dimensions 120×15×15 cm3 and 180×15×15 cm3. The self-compacting mixture contained steel fibres of varying lengths (35 and 50 mm and varying levels of their volume ratio in the mix (0.5% - 1.0% - 1.5%.

  18. High frequency of Fredrickson's phenotypes IV and IIb in Brazilians infected by human immunodeficiency virus

    Directory of Open Access Journals (Sweden)

    Oliveira Helena CF

    2005-06-01

    Full Text Available Abstract Background Human immunodeficiency virus (HIV infection is very prevalent in Brazil. HIV therapy has been recently associated with coronary heart disease (CHD. Dyslipidemia is a major risk factor for CHD that is frequently described in HIV positive patients, but very few studies have been conducted in Brazilian patients evaluating their lipid profiles. Methods In the present work, we evaluated the frequency and severity of dyslipidemia in 257 Brazilian HIV positive patients. Two hundred and thirty-eight (93% were submitted to antiretroviral therapy (224 treated with protease inhibitors plus nucleoside reverse transcriptase inhibitors, 14 treated only with the latter, 12 naive and 7 had no records of treatment. The average time on drug treatment with antiretroviral therapy was 20 months. None of the patients was under lipid lowering drugs. Cholesterol, triglyceride, phospholipid and free fatty acids were determined by enzymatic colorimetric methods. Lipoprotein profile was estimated by the Friedewald formula and Fredrickson's phenotyping was obtained by serum electrophoresis on agarose. Apolipoprotein B and AI and lipoprotein "a" were measured by nephelometry. Results The Fredrickson phenotypes were: type IIb (51%, IV (41%, IIa (7%. In addition one patient was type III and another type V. Thirty-three percent of all HIV+ patients presented serum cholesterol levels ≥ 200 mg/dL, 61% LDL-cholesterol ≥ 100 mg/dL, 65% HDL-cholesterol below 40 mg/dL, 46% triglycerides ≥ 150 mg/dL and 10% have all these parameters above the limits. Eighty-six percent of patients had cholesterol/HDL-cholesterol ratio ≥ 3.5, 22% increased lipoprotein "a", 79% increased free fatty acids and 9% increased phospholipids. The treatment with protease inhibitors plus nucleoside reverse transcriptase inhibitors increased the levels of cholesterol and triglycerides in these patients when compared with naïve patients. The HDL-cholesterol (p = 0.01 and

  19. Effects of carbon and hafnium concentrations in wrought powder-metallurgy superalloys based on nasa 2b-11 alloy

    International Nuclear Information System (INIS)

    Miner, R.V. Jr.

    1976-01-01

    A candidate alloy for advanced-temperature turbine engine disks and four modifications of that alloy with various C and Hf concentrations were produced as cross-rolled disks from prealloyed powder that was hot isostatically compacted. The mechanical properties, microstructures, and phase relations of the alloys are discussed in terms of their C and Hf concentrations. A low-C and high-Hf modification of IIB-11 had the best balance of mechanical properties for service below about 750 C. Because of their finer grain sizes, none of the powder-metallurgy alloys produced had the high-temperature rupture strength of conventionally cast and wrought IIB-11. (Author)

  20. Conceptual design of multipurpose compact research reactor

    International Nuclear Information System (INIS)

    Nagata, Hiroshi; Kusunoki, Tsuyoshi; Hori, Naohiko; Kaminaga, Masanori

    2012-01-01

    Conceptual design of the high-performance and low-cost multipurpose compact research reactor which will be expected to construct in the nuclear power plant introduction countries, started from 2010 in JAEA and nuclear-related companies in Japan. The aims of this conceptual design are to achieve highly safe reactor, economical design, high availability factor and advanced irradiation utilization. One of the basic reactor concept was determined as swimming pool type, thermal power of 10MW and water cooled and moderated reactor with plate type fuel element same as the JMTR. It is expected that the research reactors are used for human resource development, progress of the science and technology, expansion of industry use, lifetime extension of LWRs and so on. (author)

  1. Weak hydrogen bonding interactions influence slip system activity and compaction behavior of pharmaceutical powders.

    Science.gov (United States)

    Khomane, Kailas S; Bansal, Arvind K

    2013-12-01

    Markedly different mechanical behavior of powders of polymorphs, cocrystals, hydrate/anhydrate pairs, or structurally similar molecules has been attributed to the presence of active slip planes system in their crystal structures. Presence of slip planes in the crystal lattice allows easier slip under the applied compaction pressure. This allows greater plastic deformation of the powder and results into increased interparticulate bonding area and greater tensile strength of the compacts. Thus, based on this crystallographic feature, tableting performance of the active pharmaceutical ingredients can be predicted. Recently, we encountered a case where larger numbers of CH···O type interactions across the proposed slip planes hinder the slip and thus resist plastic deformation of the powder under the applied compaction pressure. Hence, attention must be given to these types of interactions while identifying slip planes by visualization method. Generally, slip planes are visualized as flat layers often strengthened by a two-dimensional hydrogen-bonding network within the layers or planes. No hydrogen bonding should exist between these layers to consider them as slip planes. Moreover, one should also check the presence of CH···O type interactions across these planes. Mercury software provides an option for visualization of these weak hydrogen bonding interactions. Hence, caution must be exercised while selecting appropriate solid form based on this crystallographic feature. © 2013 Wiley Periodicals, Inc. and the American Pharmacists Association.

  2. Does Negative Type Characterize the Round Sphere?

    DEFF Research Database (Denmark)

    Kokkendorff, Simon Lyngby

    2007-01-01

    We discuss the measure theoretic metric invariants extent, mean distance and symmetry ratio and their relation to the concept of negative type of a metric space. A conjecture stating that a compact Riemannian manifold with symmetry ratio 1 must be a round sphere, was put forward in a previous paper....... We resolve this conjecture in the class of Riemannian symmetric spaces by showing, that a Riemannian manifold with symmetry ratio 1 must be of negative type and that the only compact Riemannian symmetric spaces of negative type are the round spheres....

  3. Algebraic Bethe ansatz for U(1) invariant integrable models: Compact and non-compact applications

    International Nuclear Information System (INIS)

    Martins, M.J.; Melo, C.S.

    2009-01-01

    We apply the algebraic Bethe ansatz developed in our previous paper [C.S. Melo, M.J. Martins, Nucl. Phys. B 806 (2009) 567] to three different families of U(1) integrable vertex models with arbitrary N bond states. These statistical mechanics systems are based on the higher spin representations of the quantum group U q [SU(2)] for both generic and non-generic values of q as well as on the non-compact discrete representation of the SL(2,R) algebra. We present for all these models the explicit expressions for both the on-shell and the off-shell properties associated to the respective transfer matrices eigenvalue problems. The amplitudes governing the vectors not parallel to the Bethe states are shown to factorize in terms of elementary building blocks functions. The results for the non-compact SL(2,R) model are argued to be derived from those obtained for the compact systems by taking suitable N→∞ limits. This permits us to study the properties of the non-compact SL(2,R) model starting from systems with finite degrees of freedom.

  4. Algebraic Bethe ansatz for U(1) invariant integrable models: Compact and non-compact applications

    Science.gov (United States)

    Martins, M. J.; Melo, C. S.

    2009-10-01

    We apply the algebraic Bethe ansatz developed in our previous paper [C.S. Melo, M.J. Martins, Nucl. Phys. B 806 (2009) 567] to three different families of U(1) integrable vertex models with arbitrary N bond states. These statistical mechanics systems are based on the higher spin representations of the quantum group U[SU(2)] for both generic and non-generic values of q as well as on the non-compact discrete representation of the SL(2,R) algebra. We present for all these models the explicit expressions for both the on-shell and the off-shell properties associated to the respective transfer matrices eigenvalue problems. The amplitudes governing the vectors not parallel to the Bethe states are shown to factorize in terms of elementary building blocks functions. The results for the non-compact SL(2,R) model are argued to be derived from those obtained for the compact systems by taking suitable N→∞ limits. This permits us to study the properties of the non-compact SL(2,R) model starting from systems with finite degrees of freedom.

  5. Exotic dual of type II double field theory

    Directory of Open Access Journals (Sweden)

    Eric A. Bergshoeff

    2017-04-01

    Full Text Available We perform an exotic dualization of the Ramond–Ramond fields in type II double field theory, in which they are encoded in a Majorana–Weyl spinor of O(D,D. Starting from a first-order master action, the dual theory in terms of a tensor–spinor of O(D,D is determined. This tensor–spinor is subject to an exotic version of the (self-duality constraint needed for a democratic formulation. We show that in components, reducing O(D,D to GL(D, one obtains the expected exotically dual theory in terms of mixed Young tableaux fields. To this end, we generalize exotic dualizations to self-dual fields, such as the 4-form in type IIB string theory.

  6. Construction of CHESS compact undulator magnets at Kyma

    Science.gov (United States)

    Temnykh, Alexander B.; Lyndaker, Aaron; Kokole, Mirko; Milharcic, Tadej; Pockar, Jure; Geometrante, Raffaella

    2015-05-01

    In 2014 KYMA S.r.l. has built two CHESS Compact Undulator (CCU) magnets that are at present installed and successfully operate at the Cornell Electron Storage Ring. This type of undulator was developed for upgrade of Cornell High Energy Synchrotron Source beam-lines, but it can be used elsewhere as well. CCU magnets are compact, lightweight, cost efficient and in-vacuum compatible. They are linearly polarized undulators and have a fixed gap. Magnetic field tuning is achieved by phasing (shifting) top magnetic array relative bottom. Two CCUs constructed by KYMA S.r.l. have 28.4 mm period, 6.5 mm gap, 0.93 T peak field. Magnetic structure is of PPM type, made with NdFeB (40UH grade) permanent magnet material. Transitioning from the laboratory to industrial environment for a novel design required additional evaluation, design adjusting and extensive testing. Particular attention was given to the soldering technique used for fastening of the magnetic blocks to holders. This technique had thus far never been used before for undulator magnet construction by industry. The evaluation included tests of different types of soldering paste, measurements of strength of solder and determining the deformations of the soldered magnet and holder under simulated loading forces. This paper focuses on critical features of the CCU design, results of the soldering technique testing and the data regarding permanent magnets magnetization change due to soldering. In addition it deals with optimization-assisted assembly and the performance of the assembled devices and assesses some of the results of the CCU magnets operation at CESR.

  7. Starbursts in Blue compact dwarf galaxies

    International Nuclear Information System (INIS)

    Thuan, T.X.

    1987-01-01

    We summarize all the arguments for a bursting mode of star formation in blue compact dwarf galaxies. We show in particular how spectral synthesis of far ultraviolet spectra of Blue compact dwarf galaxy constitutes a powerful way for studying the star formation history in these galaxies. Blue compact dwarf galaxy luminosity functions show jumps and discontinuities. These jumps act like fossil records of the star-forming bursts, helping us to count and date the bursts

  8. Comparative studies of self-compacting concrete made with different generations of superplasticizers

    International Nuclear Information System (INIS)

    Harkouss, R.; Hamad, B.

    2016-01-01

    Self-compacting concrete was created as an effective solution to problems associated to low quality consolidation. Successful self-compacting concrete (SCC) mixes are designed to flow freely and cohesively without the intervention of mechanical compaction. The research presented in this paper has as objective to findthe effect of different types of superplasticizers on the performance of concrete mixes. The understanding of this technology was acquired through a comparative study of mixes made with second generation sulphonated naphthalene formaldehyde based superplasticizerand third generation polycarboxylate-based superplasticizer. To meet the pre-defined objectives, the research program was subdivided into two interdependent phases. Phase I studies the effect of second and third generation superplasticizeron the fresh and hardened properties of mortar mixes. Phase II studies the effect of second and third generation superplasticizer on the fresh and hardened properties of concrete mixes.The experimental outcomes revealed that third generation superplasticizers induce more efficient dispersion defined by superior consistency levels and increased hardened strengths. (author)

  9. Self-similar solutions with compactly supported profile of some nonlinear Schrodinger equations

    Directory of Open Access Journals (Sweden)

    Pascal Begout

    2014-04-01

    Full Text Available ``Sharp localized'' solutions (i.e. with compact support for each given time t of a singular nonlinear type Schr\\"odinger equation in the whole space $\\mathbb{R}^N$ are constructed here under the assumption that they have a self-similar structure. It requires the assumption that the external forcing term satisfies that $\\mathbf{f}(t,x=t^{-(\\mathbf{p}-2/2}\\mathbf{F}(t^{-1/2}x$ for some complex exponent $\\mathbf{p}$ and for some profile function $\\mathbf{F}$ which is assumed to be with compact support in $\\mathbb{R}^N$. We show the existence of solutions of the form $\\mathbf{u}(t,x=t^{\\mathbf{p}/2}\\mathbf{U}(t^{-1/2}x$, with a profile $\\mathbf{U}$, which also has compact support in $\\mathbb{R}^N$. The proof of the localization of the support of the profile $\\mathbf{U}$ uses some suitable energy method applied to the stationary problem satisfied by $\\mathbf{U}$ after some unknown transformation.

  10. Compact magnetic fusin reactor concepts

    International Nuclear Information System (INIS)

    Chung, K.M.

    1984-01-01

    Compact, high-power-density approaches to fusion power represent alternatives to main-line fusion concepts, Tokamaks and mirrors. If technological issues are resolved, theses approaches would yield small, low-cost fusion power plants. This survey reviews the principal physics and technology employed by leading compact magnetic fusion plants. (Author)

  11. Study on Effects of Different Replacement Rate on Bending Behavior of Big Recycled Aggregate Self Compacting Concrete

    Science.gov (United States)

    Li, Jing; Guo, Tiantian; Gao, Shuai; Jiang, Lin; Zhao, Zhijun; Wang, Yalin

    2018-03-01

    Big recycled aggregate self compacting concrete is a new type of recycled concrete, which has the advantages of low hydration heat and green environmental protection, but its bending behavior can be affected by different replacement rate. Therefor, in this paper, the research status of big Recycled aggregate self compacting concrete was systematically introduced, and the effect of different replacement rate of big recycled aggregate on failure mode, crack distribution and bending strength of the beam were studied through the bending behavior test of 4 big recycled aggregate self compacting concrete beams. The results show that: The crack distribution of the beam can be affected by the replacement rate; The failure modes of big recycled aggregate beams are the same as those of ordinary concrete; The plane section assumption is applicable to the big recycled aggregate self compacting concrete beam; The higher the replacement rate, the lower the bending strength of big recycled aggregate self compacting concrete beams.

  12. Invariant subsets under compact quantum group actions

    OpenAIRE

    Huang, Huichi

    2012-01-01

    We investigate compact quantum group actions on unital $C^*$-algebras by analyzing invariant subsets and invariant states. In particular, we come up with the concept of compact quantum group orbits and use it to show that countable compact metrizable spaces with infinitely many points are not quantum homogeneous spaces.

  13. A brilliant sandwich type fluorescent nanostructure incorporating a compact quantum dot layer and versatile silica substrates.

    Science.gov (United States)

    Huang, Liang; Wu, Qiong; Wang, Jing; Foda, Mohamed; Liu, Jiawei; Cai, Kai; Han, Heyou

    2014-03-18

    A "hydrophobic layer in silica" structure was designed to integrate a compact quantum dot (QD) layer with high quantum yield into scalable silica hosts containing desired functionality. This was based on metal affinity driven assembly of hydrophobic QDs with versatile silica substrates and homogeneous encapsulation of organosilica/silica layers.

  14. Compact versus noncompact quantum dynamics of time-dependent su(1,1)-valued Hamiltonians

    International Nuclear Information System (INIS)

    Penna, V.

    1996-01-01

    We consider the Schroedinger problem for time-dependent (TD) Hamiltonians represented by a linear combination of the compact generator and the hyperbolic generator of su(1,1). Several types of transitions, characterized by different time initial conditions on the generator coefficients, are analyzed by resorting to the harmonic oscillator model with a frequency vanishing for t→+∞. We provide examples that point out how the TD states of the transitions can be constructed either by the compact eigenvector basis or by the noncompact eigenvector basis depending on the initial conditions characterizing the frequency time behavior. Copyright copyright 1996 Academic Press, Inc

  15. Topological entropy of continuous actions of compactly generated groups

    OpenAIRE

    Schneider, Friedrich Martin

    2015-01-01

    We introduce a notion of topological entropy for continuous actions of compactly generated topological groups on compact Hausdorff spaces. It is shown that any continuous action of a compactly generated topological group on a compact Hausdorff space with vanishing topological entropy is amenable. Given an arbitrary compactly generated locally compact Hausdorff topological group $G$, we consider the canonical action of $G$ on the closed unit ball of $L^{1}(G)' \\cong L^{\\infty}(G)$ endowed with...

  16. Mappings with closed range and compactness

    International Nuclear Information System (INIS)

    Iyahen, S.O.; Umweni, I.

    1985-12-01

    The motivation for this note is the result of E.O. Thorp that a normed linear space E is finite dimensional if and only if every continuous linear map for E into any normed linear space has a closed range. Here, a class of Hausdorff topological groups is introduced; called r-compactifiable topological groups, they include compact groups, locally compact Abelian groups and locally convex linear topological spaces. It is proved that a group in this class which is separable, complete metrizable or locally compact, is necessarily compact if its image by a continuous group homomorphism is necessarily closed. It is deduced then that a Hausdorff locally convex is zero if its image by a continuous additive map is necessarily closed. (author)

  17. Controlled Compact High Voltage Power Lines

    Directory of Open Access Journals (Sweden)

    Postolati V.

    2016-04-01

    Full Text Available Nowadays modern overhead transmission lines (OHL constructions having several significant differences from conventional ones are being used in power grids more and more widely. Implementation of compact overhead lines equipped with FACTS devices, including phase angle regulator settings (compact controlled OHL, appears to be one of the most effective ways of power grid development. Compact controlled AC HV OHL represent a new generation of power transmission lines embodying recent advanced achievements in design solutions, including towers and insulation, together with interconnection schemes and control systems. Results of comprehensive research and development in relation to 110–500kV compact controlled power transmission lines together with theoretical basis, substantiation, and methodological approaches to their practical application are presented in the present paper.

  18. Compact approach to fusion power reactors

    International Nuclear Information System (INIS)

    Hagenson, R.L.; Krakowski, R.A.; Bathke, C.G.; Miller, R.L.

    1984-01-01

    The potential of the Reversed-Field Pinch (RFP) for development into an efficient, compact, copper-coil fusion reactor has been quantified by comprehensive parametric tradeoff studies. These compact systems promise to be competitive in size, power density, and cost to alternative energy sources. Conceptual engineering designs that largely substantiate these promising results have since been completed. This 1000-MWe(net) design is described along with a detailed rationale and physics/technology assessment for the compact approach to fusion

  19. Holographic duals of 3d S-fold CFTs

    Science.gov (United States)

    Assel, Benjamin; Tomasiello, Alessandro

    2018-06-01

    We construct non-geometric AdS4 solutions of IIB string theory where the fields in overlapping patches are glued by elements of the S-duality group. We obtain them by suitable quotients of compact and non-compact geometric solutions. The quotient procedure suggests CFT duals as quiver theories with links involving the so-called T [U( N)] theory. We test the validity of the non-geometric solutions (and of our proposed holographic duality) by computing the three-sphere partition function Z of the CFTs. A first class of solutions is obtained by an S-duality quotient of Janus-type non-compact solutions and is dual to 3d N=4 SCFTs; for these we manage to compute Z of the dual CFT at finite N, and it agrees perfectly with the supergravity result in the large N limit. A second class has five-branes, it is obtained by a Möbius-like S-quotient of ordinary compact solutions and is dual to 3d N=3 SCFTs. For these, Z agrees with the supergravity result if one chooses the limit carefully so that the effect of the fivebranes does not backreact on the entire geometry. Other limits suggest the existence of IIA duals.

  20. The spacetime life of a non-BPS D-particle

    International Nuclear Information System (INIS)

    Eyras, E.

    2000-04-01

    We investigate the classical geometry generated by a stable non-BPS D-particle. We consider the boundary state of a stable non-BPS D-particle in the covariant formalism in the type IIB theory orbifolded by (-1) F L ·I 4 . We calculate the scattering amplitude between two D-particles in the non-compact and compact orbifold and analyse the short and long distance behaviour. At short distances we find no force at order υ 2 for any radius, and at the critical radius we find a BPS-like behaviour up to υ 4 corrections for long and short distances. Projecting the boundary state on the massless states of the orbifold closed string spectrum we obtain the large distance behaviour of the classical solution describing this non-BPS D-particle in the non-compact and compact cases. By using the non-BPS D-particle as a probe of the background geometry of another non-BPS D-particle, we recover the no-force condition at the critical radius and the υ 2 behaviour of the probe. Moreover, assuming that the no-force persists for the complete geometry we derive part of the classical solution for the non-BPS D-particle. (author)

  1. Bitistatin-functionalized fluorescent nanodiamond particles specifically bind to purified human platelet integrin receptor αIIbβ3 and activated platelets

    Directory of Open Access Journals (Sweden)

    Marcinkiewicz C

    2017-05-01

    Full Text Available Cezary Marcinkiewicz,1,2 Jonathan A Gerstenhaber,1 Mark Sternberg,2 Peter I Lelkes,1 Giora Feuerstein1,2 1Department of Bioengineering, College of Engineering, Temple University, Philadelphia, 2Debina Diagnostic, Inc., Newton Square, PA, USA Abstract: Thromboembolic events (TEE underwrite key causes of death in developed countries. While advanced imaging technologies such as computed tomography scans serve to diagnose blood clots during acute cardiovascular events, no such technology is available in routine primary care for TEE risk assessment. Here, we describe an imaging platform technology based on bioengineered fluorescent nanodiamond particles (F-NDPs functionalized with bitistatin (Bit, a disintegrin that specifically binds to the αIIbβ3 integrin, platelet fibrinogen receptor (PFR on activated platelets. Covalent linkage of purified Bit to F-NDP was concentration-dependent and saturable, as validated by enzyme-linked immunosorbent assay using specific anti-Bit antibodies. F-NDP–Bit interacted with purified PFR, either in immobilized or soluble form. Lotrafiban, a nonpeptide, αIIbβ3 receptor antagonist, specifically blocked F-NDP–Bit–PFR complex formation. Moreover, F-NDP–Bit specifically binds to activated platelets incorporated into a clot generated by thrombin-activated rat platelet-rich plasma (PRP. Our results suggest that engineered F-NDP–Bit particles could serve as noninvasive, “real-time” optical diagnostics for clots present in blood vessels. Keywords: carbon nanoparticles, blood clots, imaging, platelet fibrinogen receptor, fluorescence, disintegrin, thromboembolic complications, thrombosis

  2. Surgical excision of Essure® devices with ESHRE Class IIb uterine malformation: sequential hysteroscopic-laparoscopic approach to the septate uterus.

    Science.gov (United States)

    Sills, E S; Palermo, G D

    2016-03-28

    While contraindications to Essure® placement have been provided by the manufacturer, there is no consensus on how best to remove these contraceptive devices. Here, we describe a non-hysterectomy removal of Essure® for a patient with a septate uterus (ESHRE Class IIb uterine malformation). A 35yr old G4 P2 presented for removal of Essure® implants after three years of gradually increasing pelvic pain, weight gain, headache, dizziness, lower extremity paresthesia, and fatigue which followed hysteroscopic sterilization (HS). Prior to HS, the patient was in good general health. She did not smoke and had never had a miscarriage. HS was performed under general anesthesia in October 2012. HSG obtained three months later, confirmed bilateral tubal occlusion but revealed an abnormal uterine cavity. A repeat HSG in 2015 showed minimal device migration, no contrast dye spill and a deeply bifid uterine cavity. At our center laparoscopic cornual dissection and bilateral partial tubal resection achieved removal of both devices intact and the patient was discharged three hours after surgery. Her postoperative recovery was uneventful. The presence of a Müllerian anomaly is a relative contraindication to the Essure® procedure. This is the first reported description of successful removal of Essure® coils in the setting of an ESHRE Class IIb uterine anomaly, and underscores the importance of careful patient selection, accurate pre-operative imaging and a conservative technique which renders hysterectomy unnecessary.

  3. Heat transfer in large compacts of SYNROC powder

    International Nuclear Information System (INIS)

    Buykx, W.J.

    1984-01-01

    The parameters determining the time required to reach temperature uniformity in a shock heated cylindrical compact of SYNROC powder are identified as the dimensions of the compact and the thermal diffusivity of the material. The effect of shape and size of the compact are discussed, and an experimental study of the factors influencing the thermal diffusivity of compacted SYNROC powder is described

  4. Treatment of bulky stage IB and IIB cervical cancers with outpatient neutron brachytherapy, external pelvic radiation and extrafascial hysterectomy

    International Nuclear Information System (INIS)

    Van Nagell, J.R.; Maruyama, Y.; Yoneda, J.; Donaldson, E.S.; Hanson, M.B.; Gallion, H.H.; Powell, D.E.; Kryscio, R.J.

    1986-01-01

    From January, 1977, to December, 1982, twenty-nine patients with bulky (>4 cms diameter) Stage IB or IIB cervical cancer were treated at the University of Kentucky Medical Center by a combination of out-patient neutron brachytherapy (Cf-252) and external pelvic radiation followed by extrafascial hysterectomy. Residual tumor was present in the hysterectomy specimens of 25 per cent. Complications during and following radiation therapy and surgery were minimal and included vaginal stenosis, proctitis, and hemorrhagic cystitis. The mean duration of hospitalization for surgery in these patients was 6.6 days (range 5-15 days) and postoperative morbidity was low. No patient required blood transfusion. Four patients developed urinary tract infections and two had superficial wound separations. Following treatment, patients were seen at monthly intervals for one year, every three months for two years, and every six months thereafter. No patient has been lost to follow-up. Two patients (7 per cent) developed tumor recurrence and have died of disease (1 of distant metastases; 1 local). The remaining 27 patients (93 per cent) are alive and well with no evidence of disease 24-89 months (mean 48 months) after therapy. No radiogenic fistulae or bowel obstruction were observed. These preliminary results suggest that the combination of outpatient neutron brachytherapy, external pelvic radiation, and extrafascial hysterectomy for patients with Stage IB and IIB cervical cancer is well tolerated. Complications associated with this treatment regimen have been minimal, and the recurrence rate is low. The duration of intracavitary neutron brachytherapy was short, and outpatient therapy was well received by patients

  5. Compact NMR

    Energy Technology Data Exchange (ETDEWEB)

    Bluemich, Bernhard; Haber-Pohlmeier, Sabina; Zia, Wasif [RWTH Aachen Univ. (Germany). Inst. fuer Technische und Makromolekulare Chemie (ITMC)

    2014-06-01

    Nuclear Magnetic Resonance (NMR) spectroscopy is the most popular method for chemists to analyze molecular structures, while Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic tool for medical doctors that provides high-contrast images of biological tissue. In both applications, the sample (or patient) is positioned inside a large, superconducting magnet to magnetize the atomic nuclei. Interrogating radio-frequency pulses result in frequency spectra that provide the chemist with molecular information, the medical doctor with anatomic images, and materials scientist with NMR relaxation parameters. Recent advances in magnet technology have led to a variety of small permanent magnets to allow compact and low-cost instruments. The goal of this book is to provide an introduction to the practical use of compact NMR at a level nearly as basic as the operation of a smart phone.

  6. On compact galaxies in the UGC catalogue

    International Nuclear Information System (INIS)

    Kogoshvili, N.G.

    1980-01-01

    A problem of separation of compact galaxies in the UGC Catalogue is considered. Value of surface brightness equal to or less than 21sup(m) was used as compactness criterion from a square second of arc. 96 galaxies, which are brighter than 14sup(m)5 satisfy this criterion. Among compact galaxies discovered in the UGC Catalogue 7% are the Zwicky galaxies, 15% belong to the Markarian galaxies and 27% of galaxies are part of a galaxy list with high surface brightness. Considerable divergence in estimates of total share of compact galaxies in the B.A. Worontsov-Veljaminov Morphological Catalogue of Galaxies (MCG) and the UGC Catalogue is noted. This divergence results from systematical underestimation of visible sizes of compact galaxies in the MCG Catalogue as compared with the UGC Catalogue [ru

  7. Placement of pre-compacted and in situ compacted dense backfill materials in shaft seals

    International Nuclear Information System (INIS)

    Martino, J.; Dixon, D.; Kim, C.S.

    2010-01-01

    in areas where instrument cables were installed) a smaller impact compactor was used. The compaction and other construction operations needed to be conducted carefully as the concrete, clay and surrounding rock mass of main shaft seal are being monitored via a suite of approximately 60 sensors that record temperature, strain, hydraulic and mechanical pressure as well as water content within the seal. Hand tamping was performed immediately around the cables as necessary to protect them. This paper presents the details of the work completed in the main shaft of late fall of 2009. The ventilation shaft clay placement will involve a volume of approximately 13 m 3 and utilize techniques developed in the TSX. Blocks will be cut as required and field fitted into the space where the seal is located. Granular or pelletized bentonite will be poured and compacted as space permits at the perimeter in any gaps that remain after block installation. This seal will not be monitored but past work has indicated that low hydraulic conductivities can be achieved under a high hydraulic gradient for clay seal components constructed from pre-compacted blocks. The operational experiences and lessons learned from installation of both clay barrier types will be discussed in the paper. (authors)

  8. A study on some properties of sintered stainless steel powder compacts with sintering conditions

    International Nuclear Information System (INIS)

    Lee, Bang Sik; Kim, Kwan Hyu; Lee, Doh Jae; Choi, Dap Chun

    1986-01-01

    Sintered specimens for the mechanical and corrosion tests were prepared from 316L, 410L and 434L stainless steel powder compacts with green densities in the range of 6.2∼7.0g/cm 3 . The experimental variables studied were green density, sintering atmosphere, temperature and time, type of lubricant used and cooling rate after sintering operation. Mechanical properties of green compacts and sintered specimens were evaluated. The corrosion tests were performed by potentiodynamic anodic polarization technique. Mechanical properties were very sensitive to the sintering atmosphere; sintering in dissociated ammonia resulted in the strengthing but embrittlement of sintered 316L, 410L and 434L strainless steel powder compacts. Their corrosion resistance was also decreased. The tensile strength was increased with increases in sintering time and temperature while the decreases in the yield strength were observed. The tensile properties of green compacts were shown to closely related to the green density. Addition of 1% acrawax as a lubricant was appeared to be most effective for the improvement of green strength. (Author)

  9. Effect of soil compactness on the growth and quality of carrot

    Directory of Open Access Journals (Sweden)

    Liisa Pietola

    1995-05-01

    Full Text Available Field experiments were performed in Southern Finland on three soil types: fine sand (1989-1991, clay (1989 and mull (1990-1991. The following soil mechanical treatments were applied to autumn ploughed land: soil loosening by ridge preparation (ridge distance 45 cm, rotary harrowing (to a depth of 20 cm, clay 15 cm, and soil compaction track by track by a tractor weighing 3 Mg (1 or 3 passes, wheel width 33 cm before seed bed preparation. One plot was untreated. These treatments were set up in April (on clay in May under moist soil conditions. Sprinkler irrigation (one application of 30 mm was applied to clay and fine sand when soil moisture in top soil had decreased to around 50% of plant-available water capacity. PVC cylinders (r = 15 cm, h = 60 cm were fixed in the experimental areas during the growing periods. At harvest, these cylinders were removed for specific analysis of tap and fibrous roots of carrot. Length and width of fibrous roots were quantified by image analysis in the USA. The impacts of soil loosening and partial compaction were determined by measuring soil physical parameters to a depth of 25 cm in mineral soils, and to greater depths in organic soil. Dry bulk densities of the plough layers increased with increasing tractor passes by 8%, 10% and 13% for fine sand, mull and clay soils, respectively. The lowest dry soil bulk density in the plough layer was obtained by rotary harrowing to a depth of 20 cm. Comparison of gamma ray transmission and gravimetric analysis indicated that dry soil bulk density was slightly lower when determined by gravimetric analysis. Increased soil bulk densities were reflected by increased water retention capacity (matric suction ≤ 10 kPa and greater penetrometer resistance. Relatively similar increases in bulk density increased the penetrometer resistance much less in mull than in fine sand. In contrast, greater bulk densities in the mull soil affected soil air composition adversely by decreasing

  10. Planar compaction of ceramic powders with mining explosives

    International Nuclear Information System (INIS)

    Stuivinga, M.; Verbeek, H.J.; Carton, E.P.

    2000-01-01

    Shock compaction experiments of B 4 C powders have been performed using a planar configuration. The powders were contained between metal plates. On top of the upper plate, having a thickness of about 10 mm, was a layer of mining explosives. For this configuration, computer simulations have been performed with use of the hydrocode Autodyn. In comparison with the cylindrical compaction process the planar compaction process appears to be quite different. The reason is the very low detonation velocity of the used mining explosives (2-4 km/s), which is much lower than the sound and shock speeds of the steel plate, in combination with the relatively large thickness of the metal layer. As a result, the nature of the compaction process of the powder initially more resembles a quasi-static compaction process than a shock compaction process. Due to the quasi-static nature of the compaction, the pressure release in the powder after compression is very gradual. Therefore, no strong rarefaction waves leading to high tensile stresses in the compact arise. Flat plates (10x10 cm, 0.6-0.8 cm thick) of Al (20-30 vol %) infiltrated B 4 C have been fabricated using this configuration

  11. Compact and energy saving magnet technology for particle accelerators

    International Nuclear Information System (INIS)

    Baurichter, A.

    2013-01-01

    Despite the fact that funding agencies and industrial users of particle accelerators get more and more alerted about costs of civil engineering, installation and operation, only little effort has been put into development of sustainable, energy and cost saving accelerator technology. In order to reduce the total-cost-of ownership of accelerator magnets, operating at high electrical power for twenty years or more, permanent magnet based Green Magnet technology has been developed at a consortium around Danfysik's R and D team. Together with our partners from ISA, Aarhus University, the Aarhus School of Engineering, the company Sintex and Aalborg University all obstacles in applying permanent magnet technology as e.g. thermal drift and inhomogeneities of magnetic fields have been overcome. The first Green Magnet has now been operated for more than half a year in an Accelerator Mass Spectrometry facility at the ETH in Zurich. The performance of this B=0.43T 90 deg. H-type bending magnet and the most recently builtB=1T, 30 deg. C-type Green Magnet for the synchrotron light source ASTRID2 at ISA in Aarhus will be presented. Danfysik also is designing, manufacturing and testing 60 compact magnet systems, developed at MAX-Lab for the new MAXIV 3.0 GeV synchrotron light source. In addition, 12 for the 1.5 GeV light source and another 12 for the new SOLARIS light source in Krakow, Poland are buying built. Up to a dozen or more magnet functions have been integrated into one yoke of these compact magnet systems, which makes the new MAXIV light sources compact, energy saving and at the same time very bright. Test results and design concepts of the new MAXIV and SOLARIS magnets will be presented. (author)

  12. Solid targetry for compact cyclotrons

    International Nuclear Information System (INIS)

    Comor, J.

    2004-01-01

    In this presentation authors present experimental results of solid targetry for compact cyclotrons. It is concluded: Solid targetry is not restricted to large accelerator centers anymore; Small and medium scale radioisotope production is feasible with compact cyclotrons; The availability of versatile solid target systems is expected to boost the radiochemistry of 'exotic' positron emitters

  13. Steady state compact toroidal plasma production

    Science.gov (United States)

    Turner, William C.

    1986-01-01

    Apparatus and method for maintaining steady state compact toroidal plasmas. A compact toroidal plasma is formed by a magnetized coaxial plasma gun and held in close proximity to the gun electrodes by applied magnetic fields or magnetic fields produced by image currents in conducting walls. Voltage supply means maintains a constant potential across the electrodes producing an increasing magnetic helicity which drives the plasma away from a minimum energy state. The plasma globally relaxes to a new minimum energy state, conserving helicity according to Taylor's relaxation hypothesis, and injecting net helicity into the core of the compact toroidal plasma. Controlling the voltage so as to inject net helicity at a predetermined rate based on dissipative processes maintains or increases the compact toroidal plasma in a time averaged steady state mode.

  14. Studies on tableting properties of lactose. Part 2. Consolidation and compaction of different types of crystalline lactose

    NARCIS (Netherlands)

    Vromans, H.; de Boer, A.H.; Bolhuis, G.K.; Lerk, C.F.; Kussendrager, K.D.; Bosch, H.

    1985-01-01

    Lactose is available in several crystalline forms, which differ in binding properties. A new method of estimating the fragmentation propensity was applied to investigate the consolidation and compaction behaviour of this excipient for direct compression. Mercury porosimetry was used to demonstrate

  15. Where are compact groups in the local Universe?

    Science.gov (United States)

    Díaz-Giménez, Eugenia; Zandivarez, Ariel

    2015-06-01

    Aims: The purpose of this work is to perform a statistical analysis of the location of compact groups in the Universe from observational and semi-analytical points of view. Methods: We used the velocity-filtered compact group sample extracted from the Two Micron All Sky Survey for our analysis. We also used a new sample of galaxy groups identified in the 2M++ galaxy redshift catalogue as tracers of the large-scale structure. We defined a procedure to search in redshift space for compact groups that can be considered embedded in other overdense systems and applied this criterion to several possible combinations of different compact and galaxy group subsamples. We also performed similar analyses for simulated compact and galaxy groups identified in a 2M++ mock galaxy catalogue constructed from the Millennium Run Simulation I plus a semi-analytical model of galaxy formation. Results: We observed that only ~27% of the compact groups can be considered to be embedded in larger overdense systems, that is, most of the compact groups are more likely to be isolated systems. The embedded compact groups show statistically smaller sizes and brighter surface brightnesses than non-embedded systems. No evidence was found that embedded compact groups are more likely to inhabit galaxy groups with a given virial mass or with a particular dynamical state. We found very similar results when the analysis was performed using mock compact and galaxy groups. Based on the semi-analytical studies, we predict that 70% of the embedded compact groups probably are 3D physically dense systems. Finally, real space information allowed us to reveal the bimodal behaviour of the distribution of 3D minimum distances between compact and galaxy groups. Conclusions: The location of compact groups should be carefully taken into account when comparing properties of galaxies in environments that are a priori different. Appendices are available in electronic form at http://www.aanda.orgFull Tables B.1 and B.2

  16. Hydraulic Yaw System for Wind Turbines with New Compact Hydraulic Motor Principle

    DEFF Research Database (Denmark)

    Sørensen, Rasmus Mørk; Hansen, Michael Rygaard; Mouritsen, Ole Ø.

    2011-01-01

    This paper presents a new hydraulic yaw system for wind turbines. The basic component is a new type of hydraulic motor characterized by an extraordinary high specific displacement yielding high output torque in a compact form. The focus in the paper is the volumetric efficiency of the motor, which...

  17. 77 FR 22805 - Meeting of the Compact Council for the National Crime Prevention and Privacy Compact; Correction

    Science.gov (United States)

    2012-04-17

    ... Compact Council (Council) created by the National Crime Prevention and Privacy Compact Act of 1998..., correct the hotel address line in ADDRESSES to read: 300 East Travis. Dated: April 10, 2012. Gary S...

  18. Compact heat and mass exchangers of the plate fin type in thermal sorption systems: Application in an absorption heat pump with the working pair CH3OH-LiBr/ZnBr2

    Science.gov (United States)

    Becker, Harry

    The possible application of Compact Heat and Mass Exchangers (CHME) in a gas fired Absorption Heat Pump (AHP) for domestic heating is studied. The above mentioned heat and mass exchangers are of the plate type. The space between the parallel and plain plates is filled up with corrugated plates of a certain height. The plain and finned plates are stacked and welded together. This gives a heat and mass exchanger which is very compact, expressed by a high area density (m2/m3). This leads to heat and mass transfer processes with small temperature and concentration differences. For testing purposes a pilot plant was built using the above type of components in order to test their heat and/or mass transfer performance. Only the generator is of the Shell And Tube (SAT) type. As the working pair, CH3OH - LiBr/ ZnBr2 was chosen, with the alcohol as the solvent and the salt mixture as the absorbent. This leads to sub atmospheric working pressures with only solvent in the vapor phase. Three series of experiments have been carried out, during which the input parameters were varied over a certain range. It is concluded that the plate fin CHMES are very suitable for application in an AHP for domestic heating purposes.

  19. Machine for compacting solid residues

    International Nuclear Information System (INIS)

    Herzog, J.

    1981-11-01

    Machine for compacting solid residues, particularly bulky radioactive residues, constituted of a horizontally actuated punch and a fixed compression anvil, in which the residues are first compacted horizontally and then vertically. Its salient characteristic is that the punch and the compression anvil have embossments on the compression side and interpenetrating plates in the compression position [fr

  20. Soil compaction and fertilization in soybean productivity

    Directory of Open Access Journals (Sweden)

    Beutler Amauri Nelson

    2004-01-01

    Full Text Available Soil compaction and fertilization affect soybean development. This study evaluated the effects of soil compaction and fertilization on soybean (Glycine max cv. Embrapa 48 productivity in a Typic Haplustox under field conditions in Jaboticabal, SP, Brazil. A completely randomized design with a 5 x 2 factorial layout (compaction vs. fertilization, with four replications in each treatment, was employed. Each experimental unit (replicate consisted of a 3.6 m² useful area. After the soil was prepared by cultivation, an 11 Mg tractor passed over it a variable number of times to create five levels of compaction. Treatments were: T0= no compaction, T1= one tractor pass, T2= two, T4= four, and T6= six passes, and no fertilizer and fertilizer to give soybean yields of 2.5 to 2.9 Mg ha-1. Soil was sampled at depths of 0.02-0.05, 0.07-0.10, and 0.15-0.18 m to determine macro and microporosity, penetration resistance (PR, and bulk density (Db. After 120 days growing under these conditions, the plants were analyzed in terms of development (plant height, number of pods, shoot dry matter per plant and weight of 100 seeds and seed productivity per hectare. Soil compaction decreased soybean development and productivity, but this effect was decreased by soil fertilization, showing that such fertilization increased soybean tolerance to soil compaction.

  1. Project of compact accelerator for cancer proton therapy; Progetto di acceleratore compatto per terapia oncologica con protoni (TOP)

    Energy Technology Data Exchange (ETDEWEB)

    Picardi, L; Ronsivalle, C; Vignati, A [ENEA, Cntro Ricerche Frascati, Rome (Italy). Dip. Innovazione

    1995-04-01

    The status of the sub-project `Compact Accelerator` in the framework of the Hadrontherapy Project leaded by Prof. Amaldi is described. Emphasis is given to the reasons of the use of protons for radiotherapy applications, to the results of the preliminary design studies of four types of accelerators as possible radiotherapy dedicated `Compact Accelerator` and to the scenario of the fonts of financial resources.

  2. Aligning laboratory and field compaction practices for asphalt - the influence of compaction temperature on mechanical properties

    NARCIS (Netherlands)

    Bijleveld, Frank; Miller, Seirgei Rosario; de Bondt, A.H.; Doree, Andries G.

    2015-01-01

    The approach used to identify a compaction temperature in the laboratory, based on binder viscosity, provides a single compaction temperature whereas, on-site, a roller operates within a temperature window. The effect on the density and mechanical properties of rolling during a temperature window

  3. The unique structural parameters of the underlying host galaxies in blue compact dwarfs

    International Nuclear Information System (INIS)

    Janowiecki, Steven; Salzer, John J.

    2014-01-01

    The nature of possible evolutionary pathways between various types of dwarf galaxies is still not fully understood. Blue compact dwarf galaxies (BCDs) provide a unique window into dwarf galaxy formation and evolution and are often thought of as an evolutionary stage between different classes of dwarf galaxies. In this study we use deep optical and near-infrared observations of the underlying hosts of BCDs in order to study the structural differences between different types of dwarf galaxies. When compared with dwarf irregular galaxies of similar luminosities, we find that the underlying hosts of BCDs have significantly more concentrated light distributions, with smaller scale lengths and brighter central surface brightnesses. We demonstrate here that the underlying hosts of BCDs are distinct from the broad continuum of typical dwarf irregular galaxies, and that it is unlikely that most dwarf irregular galaxies can transform into a BCD or vice versa. Furthermore, we find that the starburst in a BCD only brightens it on average by ∼0.8 mag (factor of two), in agreement with other studies. It appears that a BCD is a long-lived and distinct type of dwarf galaxy that exhibits an exceptionally concentrated matter distribution. We suggest that it is this compact mass distribution that enables the strong star formation events that characterize this class of dwarf galaxy, that the compactness of the underlying host can be used as a distinguishing parameter between BCDs and other dwarf galaxies, and that it can also be used to identify BCDs which are not currently experiencing an intense starburst event.

  4. Roller compaction of moist pharmaceutical powders.

    Science.gov (United States)

    Wu, C-Y; Hung, W-L; Miguélez-Morán, A M; Gururajan, B; Seville, J P K

    2010-05-31

    The compression behaviour of powders during roller compaction is dominated by a number of factors, such as process conditions (roll speed, roll gap, feeding mechanisms and feeding speed) and powder properties (particle size, shape, moisture content). The moisture content affects the powder properties, such as the flowability and cohesion, but it is not clear how the moisture content will influence the powder compression behaviour during roller compaction. In this study, the effect of moisture contents on roller compaction behaviour of microcrystalline cellulose (MCC, Avicel PH102) was investigated experimentally. MCC samples of different moisture contents were prepared by mixing as-received MCC powder with different amount of water that was sprayed onto the powder bed being agitated in a rotary mixer. The flowability of these samples were evaluated in terms of the poured angle of repose and flow functions. The moist powders were then compacted using the instrumented roller compactor developed at the University of Birmingham. The flow and compression behaviour during roller compaction and the properties of produced ribbons were examined. It has been found that, as the moisture content increases, the flowability of moist MCC powders decreases and the powder becomes more cohesive. As a consequence of non-uniform flow of powder into the compaction zone induced by the friction between powder and side cheek plates, all produced ribbons have a higher density in the middle and lower densities at the edges. For the ribbons made of powders with high moisture contents, different hydration states across the ribbon width were also identified from SEM images. Moreover, it was interesting to find that these ribbons were split into two halves. This is attributed to the reduction in the mechanical strength of moist powder compacts with high moisture contents produced at high compression pressures. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  5. Bone compaction enhances fixation of weightbearing titanium implants

    DEFF Research Database (Denmark)

    Kold, Søren; Rahbek, Ole; Vestermark, Marianne

    2005-01-01

    are weightbearing, the effects of compaction on weightbearing implants were examined. The hypothesis was that compaction would increase implant fixation compared with conventional drilling. Porous-coated titanium implants were inserted bilaterally into the weightbearing portion of the femoral condyles of dogs....... In each dog, one knee had the implant cavity prepared with drilling, and the other knee was prepared with compaction. Eight dogs were euthanized after 2 weeks, and eight dogs were euthanized after 4 weeks. Femoral condyles from an additional eight dogs represented Time 0. Compacted specimens had higher...... bone-implant contact and periimplant bone density at 0 and 2 weeks, but not at 4 weeks. A biphasic response of compaction was found with a pushout test, as compaction increased ultimate shear strength and energy absorption at 0 and 4 weeks, but not at 2 weeks. This biphasic response indicates...

  6. On the stability of non-supersymmetric supergravity solutions

    Science.gov (United States)

    Imaanpur, Ali; Zameni, Razieh

    2017-09-01

    We examine the stability of some non-supersymmetric supergravity solutions that have been found recently. The first solution is AdS5 ×M6, for M6 an stretched CP3. We consider breathing and squashing mode deformations of the metric, and find that the solution is stable against small fluctuations of this kind. Next we consider type IIB solution of AdS2 ×M8, where the compact space is a U (1) bundle over N (1 , 1). We study its stability under the deformation of M8 and the 5-form flux. In this case we also find that the solution is stable under small fluctuation modes of the corresponding deformations.

  7. On the stability of non-supersymmetric supergravity solutions

    Directory of Open Access Journals (Sweden)

    Ali Imaanpur

    2017-09-01

    Full Text Available We examine the stability of some non-supersymmetric supergravity solutions that have been found recently. The first solution is AdS5×M6, for M6 an stretched CP3. We consider breathing and squashing mode deformations of the metric, and find that the solution is stable against small fluctuations of this kind. Next we consider type IIB solution of AdS2×M8, where the compact space is a U(1 bundle over N(1,1. We study its stability under the deformation of M8 and the 5-form flux. In this case we also find that the solution is stable under small fluctuation modes of the corresponding deformations.

  8. Gamma-Rays from Galactic Compact Sources

    Science.gov (United States)

    Kaaret, Philip

    2007-04-01

    Recent discoveries have revealed many sources of TeV photons in our Mikly Way galaxy powered by compact objects, either neutron stars or black holes. These objects must be powerful particle accelerators, some with peak energies of at least 100 TeV, and may be neutrino, as well as photon, sources. Future TeV observations will enable us to address key questions concerning particle acceleration by compact objects including the fraction of energy which accreting black holes channel into relativstic jet production, whether the compact object jets are leptonic or hadronic, and the mechanism by which pulsar winds accelerate relativistic particles. We report on work done related to compact Galactic objects in preparation of a White Paper on the status and future of ground-based gamma-ray astronomy requested by the Division of Astrophysics of the American Physical Society.

  9. Solubility on compact subsets for differential equations with real principal pencil of symbols

    International Nuclear Information System (INIS)

    Shananin, N A

    2006-01-01

    The central result is a theorem on the solubility on compact subsets for differential equations of quasiprincipal type with real principal pencil of symbols. The proof is based on the analysis of the microlocal structure of the singularities of solutions of equations in this class.

  10. Correlating particle hardness with powder compaction performance.

    Science.gov (United States)

    Cao, Xiaoping; Morganti, Mikayla; Hancock, Bruno C; Masterson, Victoria M

    2010-10-01

    Assessing particle mechanical properties of pharmaceutical materials quickly and with little material can be very important to early stages of pharmaceutical research. In this study, a wide range of pharmaceutical materials were studied using atomic force microscopy (AFM) nanoindentation. A significant amount of particle hardness and elastic modulus data were provided. Moreover, powder compact mechanical properties of these materials were investigated in order to build correlation between the particle hardness and powder compaction performance. It was found that the materials with very low or high particle hardness most likely exhibit poor compaction performance while the materials with medium particle hardness usually have good compaction behavior. Additionally, the results from this study enriched Hiestand's special case concept on particle hardness and powder compaction performance. This study suggests that the use of AFM nanoindentation can help to screen mechanical properties of pharmaceutical materials at early development stages of pharmaceutical research.

  11. Compacting biomass waste materials for use as fuel

    Science.gov (United States)

    Zhang, Ou

    Every year, biomass waste materials are produced in large quantity. The combustibles in biomass waste materials make up over 70% of the total waste. How to utilize these waste materials is important to the nation and the world. The purpose of this study is to test optimum processes and conditions of compacting a number of biomass waste materials to form a densified solid fuel for use at coal-fired power plants or ordinary commercial furnaces. Successful use of such fuel as a substitute for or in cofiring with coal not only solves a solid waste disposal problem but also reduces the release of some gases from burning coal which cause health problem, acid rain and global warming. The unique punch-and-die process developed at the Capsule Pipeline Research Center, University of Missouri-Columbia was used for compacting the solid wastes, including waste paper, plastics (both film and hard products), textiles, leaves, and wood. The compaction was performed to produce strong compacts (biomass logs) under room temperature without binder and without preheating. The compaction conditions important to the commercial production of densified biomass fuel logs, including compaction pressure, pressure holding time, back pressure, moisture content, particle size, binder effects, and mold conditions were studied and optimized. The properties of the biomass logs were evaluated in terms of physical, mechanical, and combustion characteristics. It was found that the compaction pressure and the initial moisture content of the biomass material play critical roles in producing high-quality biomass logs. Under optimized compaction conditions, biomass waste materials can be compacted into high-quality logs with a density of 0.8 to 1.2 g/cm3. The logs made from the combustible wastes have a heating value in the range 6,000 to 8,000 Btu/lb which is only slightly (10 to 30%) less than that of subbituminous coal. To evaluate the feasibility of cofiring biomass logs with coal, burn tests were

  12. Compact instrument for fluorescence image-guided surgery

    Science.gov (United States)

    Wang, Xinghua; Bhaumik, Srabani; Li, Qing; Staudinger, V. Paul; Yazdanfar, Siavash

    2010-03-01

    Fluorescence image-guided surgery (FIGS) is an emerging technique in oncology, neurology, and cardiology. To adapt intraoperative imaging for various surgical applications, increasingly flexible and compact FIGS instruments are necessary. We present a compact, portable FIGS system and demonstrate its use in cardiovascular mapping in a preclinical model of myocardial ischemia. Our system uses fiber optic delivery of laser diode excitation, custom optics with high collection efficiency, and compact consumer-grade cameras as a low-cost and compact alternative to open surgical FIGS systems. Dramatic size and weight reduction increases flexibility and access, and allows for handheld use or unobtrusive positioning over the surgical field.

  13. Performance of a compact solar absorption cooling system

    International Nuclear Information System (INIS)

    Mulyanef; Kamaruzzaman Sopian

    2006-01-01

    This paper describes the performance of a compact solar absorption system. Purpose of compact solar is collector, generator and condenser in one unit. At present, two types of absorption cooling systems are marketed: the lithium bromide-water system and the ammonia-water system. In the lithium bromide-water system, water vapor is the refrigerant and ammonia water system where ammonia is the refrigerant. In addition, the ammonia-water system requires higher generator temperature 120 o C to 150 o C than a flat-plate solar collector can provide without special techniques. The lithium bromide-water system operates satisfactorily at a generator temperature of 75 o C to 100 o C, achievable by a flat-plate collector. The lithium bromide-water system also has a higher COP than the ammonia-water system. The disadvantage of the lithium bromide-water systems is that the evaporators cannot operate at temperature below 0 o C since the refrigerant is water. The Coefficient of Performance (COP) system is 0.62 and the concentration of LiBr-H 2 O is 50%

  14. A structural investigation into the compaction behavior of pharmaceutical composites using powder X-ray diffraction and total scattering analysis.

    Science.gov (United States)

    Moore, Michael D; Steinbach, Alison M; Buckner, Ira S; Wildfong, Peter L D

    2009-11-01

    To use advanced powder X-ray diffraction (PXRD) to characterize the structure of anhydrous theophylline following compaction, alone, and as part of a binary mixture with either alpha-lactose monohydrate or microcrystalline cellulose. Compacts formed from (1) pure theophylline and (2) each type of binary mixture were analyzed intact using PXRD. A novel mathematical technique was used to accurately separate multi-component diffraction patterns. The pair distribution function (PDF) of isolated theophylline diffraction data was employed to assess structural differences induced by consolidation and evaluated by principal components analysis (PCA). Changes induced in PXRD patterns by increasing compaction pressure were amplified by the PDF. Simulated data suggest PDF dampening is attributable to molecular deviations from average crystalline position. Samples compacted at different pressures were identified and differentiated using PCA. Samples compacted at common pressures exhibited similar inter-atomic correlations, where excipient concentration factored in the analyses involving lactose. Practical real-space structural analysis of PXRD data by PDF was accomplished for intact, compacted crystalline drug with and without excipient. PCA was used to compare multiple PDFs and successfully differentiated pattern changes consistent with compaction-induced disordering of theophylline as a single component and in the presence of another material.

  15. Effect of slash on forwarder soil compaction

    Science.gov (United States)

    Timothy P. McDonald; Fernando Seixas

    1997-01-01

    A study of the effect of slash on forwarder soil compaction was carried out. The level of soil compaction at two soil moisture contents, three slash densities (0, 10, and 20 kg/m2), and two levels of traffic (one and five passes) were measured. Results indicated that, on dry, loamy sand soils, the presence of slash did not decrease soil compaction after one forwarder...

  16. Ciprofloxacin DPI: a randomised, placebo-controlled, phase IIb efficacy and safety study on cystic fibrosis.

    Science.gov (United States)

    Dorkin, Henry L; Staab, Doris; Operschall, Elisabeth; Alder, Jeff; Criollo, Margarita

    2015-01-01

    Treatment of infective bronchitis involving Pseudomonas aeruginosa is a cornerstone of care in patients with cystic fibrosis (CF). This phase IIb, randomised, double-blind, placebo-controlled study assessed the efficacy and safety of ciprofloxacin dry powder for inhalation (DPI) in this population. Patients with CF, ≥12 years of age (N=286), were randomised to ciprofloxacin DPI (32.5 mg (n=93) or 48.75 mg (n=93)), or corresponding placebo (32.5 mg, n=65; 48.75 mg, n=35) twice daily for 28 days. The primary objective was the change in forced expiratory volume in 1 s (FEV1) from baseline (day 0) to end of treatment (day 29) in the intent-to-treat population for ciprofloxacin DPI compared with the corresponding placebo group. The primary effectiveness objective was not met; there were no significant differences in change in FEV1 between ciprofloxacin DPI and the corresponding placebo group for either dose (p=0.154). However, in pooled analyses, FEV1 decline from baseline to treatment end was significantly lower with ciprofloxacin DPI than with placebo (pooled data; p=0.02). Ciprofloxacin DPI showed positive effects on sputum bacterial load and quality of life, but these effects were not maintained at the 4-week follow-up. Ciprofloxacin DPI was well tolerated and there were no significant differences in type/incidence of treatment-emergent adverse events by treatment group (p=0.115). Further investigations are needed to determine the full scope of the beneficial effects of ciprofloxacin DPI for patients with CF. Clinicaltrials.gov NCT00645788; EudraCT 2008-008314-40.

  17. Compacted cancellous bone has a spring-back effect

    DEFF Research Database (Denmark)

    Kold, S; Bechtold, JE; Ding, Ming

    2003-01-01

    A new surgical technique, compaction, has been shown to improve implant fixation. It has been speculated that the enhanced implant fixation with compaction could be due to a spring-back effect of compacted bone. However, such an effect has yet to be shown. Therefore we investigated in a canine mo....... Thus we found a spring-back effect of compacted bone, which may be important for increasing implant fixation by reducing initial gaps between the implant and bone....

  18. Effect of repeated compaction of tablets on tablet properties and work of compaction using an instrumented laboratory tablet press.

    Science.gov (United States)

    Gamlen, Michael John Desmond; Martini, Luigi G; Al Obaidy, Kais G

    2015-01-01

    The repeated compaction of Avicel PH101, dicalcium phosphate dihydrate (DCP) powder, 50:50 DCP/Avicel PH101 and Starch 1500 was studied using an instrumented laboratory tablet press which measures upper punch force, punch displacement and ejection force and operates using a V-shaped compression profile. The measurement of work compaction was demonstrated, and the test materials were ranked in order of compaction behaviour Avicel PH101 > DCP/Avicel PH101 > Starch > DCP. The behaviour of the DCP/Avicel PH101 mixture was distinctly non-linear compared with the pure components. Repeated compaction and precompression had no effect on the tensile fracture strength of Avicel PH101 tablets, although small effects on friability and disintegration time were seen. Repeated compaction and precompression reduced the tensile strength and the increased disintegration time of the DCP tablets, but improved the strength and friability of Starch 1500 tablets. Based on the data reported, routine laboratory measurement of tablet work of compaction may have potential as a critical quality attribute of a powder blend for compression. The instrumented press was suitable for student use with minimal supervisor input.

  19. Evaluation of automatic vacuum- assisted compaction solutions

    Directory of Open Access Journals (Sweden)

    M. Brzeziński

    2011-01-01

    Full Text Available Currently on the mould-making machines market the companies like: DiSA, KUENKEL WAGNER, HAFLINGER, HEINRICH WAGNER SINTO, HUNTER, SAVELLI AND TECHNICAL play significant role. These companies are the manufacturers of various solutions in machines and instalations applied in foundry engineering. Automatic foundry machines for compaction of green sand have the major role in mechanisation and automation processes of making the mould. The concept of operation of automatic machines is based on the static and dynamic methods of compacting the green sand. The method which gains the importance is the compacting method by using the energy of the air pressure. It's the initial stage or the supporting process of compacting the green sand. However in the automatic mould making machines using this method it's essential to use the additional compaction of the mass in order to receive the final parameters of the form. In the constructional solutions of the machines there is the additional division which concerns the method of putting the sand into the mould box. This division distinquishes the transport of the sand with simultaneous compaction or the putting of the sand without the pre-compaction. As the solutions of the major manufacturers are often the subject for application in various foundries, the authors of the paper would like/have the confidence to present their own evaluation process confirmed by their own researches and independent analysis of the producers' solutions.

  20. Compact Antenna Range

    Data.gov (United States)

    Federal Laboratory Consortium — Facility consists of a folded compact antenna range including a computer controlled three axis position table, parabolic reflector and RF sources for the measurement...

  1. Linear Shrinkage Behaviour of Compacted Loam Masonry Blocks

    Directory of Open Access Journals (Sweden)

    NAWAB ALI LAKHO

    2017-04-01

    Full Text Available Walls of wet loam, used in earthen houses, generally experience more shrinkage which results in cracks and less compressive strength. This paper presents a technique of producing loam masonry blocks that are compacted in drained state during casting process in order to minimize shrinkage. For this purpose, loam masonry blocks were cast and compacted at a pressure of 6 MPa and then dried in shade by covering them in plastic sheet. The results show that linear shrinkage of 2% occurred which is smaller when compared to un-compacted wet loam walls. This implies that the loam masonry blocks compacted in drained state is expected to perform better than un-compacted wet loam walls.

  2. Formation of a compact toroid for enhanced efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Mozgovoy, A. G. [P.N. Lebedev Physical Institute, Moscow 119991 (Russian Federation); Romadanov, I. V.; Ryzhkov, S. V., E-mail: ryzhkov@power.bmstu.ru [Bauman Moscow State Technical University, Moscow 105005 (Russian Federation)

    2014-02-15

    We report here our results on the formation of a plasma configuration with the generic name of compact toroid (CT). A method of compact toroid formation to confine, heat and compress a plasma is investigated. Formation of a compact torus using an additional toroidal magnetic field helps to increase the plasma current to a maintainable level of the original magnetic field. We design the Compact Toroid Challenge (CTC) experiment in order to improve the magnetic flux trapping during field reversal in the formation of a compact toroid. The level of the magnetic field immersed in the plasma about 70% of the primary field is achieved. The CTC device and scheme of high level capturing of magnetic flux are presented.

  3. Compaction of amorphous iron–boron powder

    DEFF Research Database (Denmark)

    Hendriksen, Peter Vang; Mørup, Steen; Koch, Christian

    1993-01-01

    Large scale practical use of bulk amorphous alloys requires the capability of molding the material to a desired design, for instance by compaction of an amorphous powder. This is a difficult task because the sintering temperature is limited by the crystallization temperature of the alloy.1 Here we......, should facilitate a compaction. The passivation layer, however, impedes a compaction. Isostatic pressing at 540 K at a pressure of 200 MPa clearly illustrated this; pellets pressed from passivated powder were much more brittle than pellets pressed from unpassivated powder. The density of the pellets...... was very low ([approximately-equal-to]25% of the density of bulk FeB). We have designed a die for uniaxial pressing in which the compaction can be performed without exposing the powder to air and have obtained densities larger than 60% of that of bulk FeB. We have reported studies of the dependence...

  4. Principal State Analysis for a Compact in-Line Fiber Polarization Controller

    International Nuclear Information System (INIS)

    Li Zheng-Yong; Wu Chong-Qing; Wang Zhi-Hao; Qin Tao; Wang Yi-Xu

    2013-01-01

    A compact in-line fiber-based polarization controller (FPC) made of a rotatable fiber squeezer is investigated in detail with the Mueller matrix model established based on the generalized principal state of polarization (PSP). The PSP caused by the fiber squeezing is in the equator plane, which turns around S 3 axis on the Poincaré sphere when rotating the squeezer. Subsequently, a programmable polarization control method is proposed to realize the polarization conversion between arbitrary polarization states, in which only two parameters of phase shift and rotation angle need to be controlled. This type of FPC, which has a highly compact structure, lower insertion loss, and can be directly embedded into any fiber devices without any extra delay, will be an ideal PC for high-speed optical communication and all-optical signal processing

  5. Isometric coactions of compact quantum groups on compact ...

    Indian Academy of Sciences (India)

    a compact quantum metric space in the framework of Rieffel, where the ... This problem can be formulated and studied in various settings. ... The spaces we are interested in this paper are metric spaces, both classical and quantum. ... He has given a definition for a quantum symmetry of a classical ...... by the construction of I.

  6. Ibrutinib Inhibits Platelet Integrin αIIbβ3 Outside-In Signaling and Thrombus Stability But Not Adhesion to Collagen.

    Science.gov (United States)

    Bye, Alexander P; Unsworth, Amanda J; Vaiyapuri, Sakthivel; Stainer, Alexander R; Fry, Michael J; Gibbins, Jonathan M

    2015-11-01

    Ibrutinib is an irreversible Bruton tyrosine kinase inhibitor approved for treatment of Waldenstrom macroglobulinemia, chronic lymphocytic leukemia, and mantle cell lymphoma that increases the risk of bleeding among patients. Platelets from ibrutinib-treated patients exhibit deficiencies in collagen-evoked signaling in suspension; however, the significance of this observation and how it relates to bleeding risk is unclear, as platelets encounter immobile collagen in vivo. We sought to clarify the effects of ibrutinib on platelet function to better understand the mechanism underlying bleeding risk. By comparing signaling in suspension and during adhesion to immobilized ligands, we found that the collagen signaling deficiency caused by ibrutinib is milder during adhesion to immobilized collagen. We also found that platelets in whole blood treated with ibrutinib adhered to collagen under arterial shear but formed unstable thrombi, suggesting that the collagen signaling deficiency caused by ibrutinib may not be the predominant cause of bleeding in vivo. However, clot retraction and signaling evoked by platelet adhesion to immobilized fibrinogen were also inhibited by ibrutinib, indicating that integrin αIIbβ3 outside-in signaling is also effected in addition to GPVI signaling. When ibrutinib was combined with the P2Y12 inhibitor, cangrelor, thrombus formation under arterial shear was inhibited additively. These findings suggest that (1) ibrutinib causes GPVI and integrin αIIbβ3 platelet signaling deficiencies that result in formation of unstable thrombi and may contribute toward bleeding observed in vivo and (2) combining ibrutinib with P2Y12 antagonists, which also inhibit thrombus stability, may have a detrimental effect on hemostasis. © 2015 American Heart Association, Inc.

  7. Temperature evolution during compaction of pharmaceutical powders.

    Science.gov (United States)

    Zavaliangos, Antonios; Galen, Steve; Cunningham, John; Winstead, Denita

    2008-08-01

    A numerical approach to the prediction of temperature evolution in tablet compaction is presented here. It is based on a coupled thermomechanical finite element analysis and a calibrated Drucker-Prager Cap model. This approach is capable of predicting transient temperatures during compaction, which cannot be assessed by experimental techniques due to inherent test limitations. Model predictions are validated with infrared (IR) temperature measurements of the top tablet surface after ejection and match well with experiments. The dependence of temperature fields on speed and degree of compaction are naturally captured. The estimated transient temperatures are maximum at the end of compaction at the center of the tablet and close to the die wall next to the powder/die interface.

  8. 'Crescent'-shaped tokamak for compact ignition

    International Nuclear Information System (INIS)

    Yamazaki, K.; Reiersen, W.T.

    1985-12-01

    A compact high-beta tokamak configuration with ''crescent''-shaped (or ''boomerang''-shaped) cross-section is proposed as a next-generation ignition machine. This configuration with a small indentation but a large triangularity is more compact than the normal dee-shaped design because of its high-beta characteristics in the first-second transition regime of stability. This may also be a more reliable next-generation compact device than the bean-shaped design with large indentation and small triangularity, because this design dose not rely on the second stability and is easily extendable from the present dee-shaped design. (author)

  9. Generalised model for anisotropic compact stars

    Energy Technology Data Exchange (ETDEWEB)

    Maurya, S.K. [University of Nizwa, Department of Mathematical and Physical Sciences College of Arts and Science, Nizwa (Oman); Gupta, Y.K. [Raj Kumar Goel Institute of Technology, Department of Mathematics, Ghaziabad, Uttar Pradesh (India); Ray, Saibal [Government College of Engineering and Ceramic Technology, Department of Physics, Kolkata, West Bengal (India); Deb, Debabrata [Indian Institute of Engineering Science and Technology, Shibpur, Department of Physics, Howrah, West Bengal (India)

    2016-12-15

    In the present investigation an exact generalised model for anisotropic compact stars of embedding class 1 is sought with a general relativistic background. The generic solutions are verified by exploring different physical aspects, viz. energy conditions, mass-radius relation, stability of the models, in connection to their validity. It is observed that the model presented here for compact stars is compatible with all these physical tests and thus physically acceptable as far as the compact star candidates RXJ 1856-37, SAX J 1808.4-3658 (SS1) and SAX J 1808.4-3658 (SS2) are concerned. (orig.)

  10. 'Crescent'-shaped tokamak for compact ignition

    International Nuclear Information System (INIS)

    Yamazaki, K.; Reiersen, W.T.

    1986-01-01

    A compact high-beta tokamak configuration with ''crescent''-shaped (or ''boomerang''-shaped) cross section is proposed as a next-generation ignition machine. This configuration with a small indentation but a large triangularity is more compact than the normal dee-shaped design because of its high-beta characteristics in the first-second transition regime of stability. This may also be a more reliable next-generation compact device than the bean-shaped design with large indentation and small triangularity, because this design does not rely on the second stability and is easily extendable from the present dee-shaped design. (author)

  11. The relationship between the particle properties, mechanical behavior, and surface roughness of some pharmaceutical excipient compacts

    International Nuclear Information System (INIS)

    Narayan, Padma; Hancock, Bruno C.

    2003-01-01

    supported the model descriptions and hypotheses. The initial average particle size of the excipients did not directly correlate with compact roughness, probably due to particle deformation during compression. Average roughness values ranged between 0.1 and 1.0 μm for the compacted materials studied. The mechanical properties of the compacts, such as indentation hardness, elastic modulus, and brittle fracture index were also correlated with the roughness values. Pertinent correlations were found between average roughness, compact mechanical properties and the excipient type (either brittle or ductile). From this study, it can be concluded that brittle excipient powders generally produced smooth and brittle compacts, and plastic materials produced rough and ductile compacts. Surface roughness was hence found to be a useful descriptive property for pharmaceutical composites and supporting a model based on the excipient powder properties

  12. The relationship between the particle properties, mechanical behavior, and surface roughness of some pharmaceutical excipient compacts

    Energy Technology Data Exchange (ETDEWEB)

    Narayan, Padma; Hancock, Bruno C

    2003-08-25

    cracks or surface defects. These findings supported the model descriptions and hypotheses. The initial average particle size of the excipients did not directly correlate with compact roughness, probably due to particle deformation during compression. Average roughness values ranged between 0.1 and 1.0 {mu}m for the compacted materials studied. The mechanical properties of the compacts, such as indentation hardness, elastic modulus, and brittle fracture index were also correlated with the roughness values. Pertinent correlations were found between average roughness, compact mechanical properties and the excipient type (either brittle or ductile). From this study, it can be concluded that brittle excipient powders generally produced smooth and brittle compacts, and plastic materials produced rough and ductile compacts. Surface roughness was hence found to be a useful descriptive property for pharmaceutical composites and supporting a model based on the excipient powder properties.

  13. Development of compact toroids injector for direct plasma controls

    International Nuclear Information System (INIS)

    Azuma, K.; Oda, Y.; Onozuka, M.; Uyama, T.; Nagata, M.; Fukumoto, N.

    1995-01-01

    The application of the compact toroids injector for direct plasma controls has been investigated. The compact toroids injection can fuel particles directly into the core of the plasma and modify the plasma profiles at the desired locations. The acceleration tests of the compact toroids have been conducted at Himeji Institute of Technology. The tests showed that the hydrogen compact toroid was accelerated up to 80km/s and the plasma density of the compact toroid was compressed to 1.2 x 10 21 m -3 . (orig.)

  14. The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS).

    Science.gov (United States)

    Tsume, Yasuhiro; Matsui, Kazuki; Searls, Amanda L; Takeuchi, Susumu; Amidon, Gregory E; Sun, Duxin; Amidon, Gordon L

    2017-05-01

    The development of formulations and the assessment of oral drug absorption for Biopharmaceutical Classification System (BCS) class IIb drugs is often a difficult issue due to the potential for supersaturation and precipitation in the gastrointestinal (GI) tract. The physiological environment in the GI tract largely influences in vivo drug dissolution rates of those drugs. Thus, those physiological factors should be incorporated into the in vitro system to better assess in vivo performance of BCS class IIb drugs. In order to predict oral bioperformance, an in vitro dissolution system with multiple compartments incorporating physiologically relevant factors would be expected to more accurately predict in vivo phenomena than a one-compartment dissolution system like USP Apparatus 2 because, for example, the pH change occurring in the human GI tract can be better replicated in a multi-compartmental platform. The Gastrointestinal Simulator (GIS) consists of three compartments, the gastric, duodenal and jejunal chambers, and is a practical in vitro dissolution apparatus to predict in vivo dissolution for oral dosage forms. This system can demonstrate supersaturation and precipitation and, therefore, has the potential to predict in vivo bioperformance of oral dosage forms where this phenomenon may occur. In this report, in vitro studies were performed with dipyridamole and ketoconazole to evaluate the precipitation rates and the relationship between the supersaturation levels and oral absorption of BCS class II weak base drugs. To evaluate the impact of observed supersaturation levels on oral absorption, a study utilizing the GIS in combination with mouse intestinal infusion was conducted. Supersaturation levels observed in the GIS enhanced dipyridamole and ketoconazole absorption in mouse, and a good correlation between their supersaturation levels and their concentration in plasma was observed. The GIS, therefore, appears to represent in vivo dissolution phenomena and

  15. N=1 domain wall solutions of massive type II supergravity as generalized geometries

    International Nuclear Information System (INIS)

    Louis, J.

    2006-05-01

    We study N=1 domain wall solutions of type IIB supergravity compactified on a Calabi-Yau manifold in the presence of RR and NS electric and magnetic fluxes. We show that the dynamics of the scalar fields along the direction transverse to the domain wall is described by gradient flow equations controlled by a superpotential W. We then provide a geometrical interpretation of the gradient flow equations in terms of the mirror symmetric compactification of type IIA. They correspond to a set of generalized Hitchin flow equations of a manifold with SU(3) x SU(3)structure which is fibered over the direction transverse to the domain wall. (Orig.)

  16. Co-compact Gabor Systems on Locally Compact Abelian Groups

    DEFF Research Database (Denmark)

    Jakobsen, Mads Sielemann; Lemvig, Jakob

    2016-01-01

    In this work we extend classical structure and duality results in Gabor analysis on the euclidean space to the setting of second countable locally compact abelian (LCA) groups. We formulate the concept of rationally oversampling of Gabor systems in an LCA group and prove corresponding characteriz...

  17. Agglomeration of powders with a new-coupled vibration-compaction device

    Directory of Open Access Journals (Sweden)

    Serris Eric

    2017-01-01

    Full Text Available Inorganic powder recycling should be a crucial process for the “smart factories” in the future. A complex three-phase system (bauxite mixed with ordinary Portland cement and water with a new-coupled vibration-compaction device is studied. The compressive stress of compacts seems to be improved by using this device at low compaction pressure leaving the other characteristics unchanged. The tomographic study of macroscopic porosities shows differences in the pores repartitions inside vibrated and untreated compacts. Classic porosity repartition is shown in the classic compacted bauxite compacts whereas in the vibrated-compacted bauxite exhibits inhomogeneities. Despite this, we find these results quite promising for further investigations.

  18. Impact Compaction of a Granular Material

    Science.gov (United States)

    Fenton, Gregg; Asay, Blaine; Todd, Steve; Grady, Dennis

    2017-06-01

    The dynamic behavior of granular materials has importance to a variety of engineering applications. Although, the mechanical behavior of granular materials have been studied extensively for several decades, the dynamic behavior of these materials remains poorly understood. High-quality experimental data are needed to improve our general understanding of granular material compaction physics. This paper describes how an instrumented plunger impact system can be used to measure the compaction process for granular materials at high and controlled strain rates and subsequently used for computational modelling. The experimental technique relies on a gas-gun driven plunger system to generate a compaction wave through a volume of granular material. This volume of material has been redundantly instrumented along the bed length to track the progression of the compaction wave, and the piston displacement is measured with Photon Doppler Velocimetry (PDV). Using the gathered experimental data along with the initial material tap density, a granular material equation of state can be determined.

  19. F-theory and AdS3/CFT2 (2, 0)

    Science.gov (United States)

    Couzens, Christopher; Martelli, Dario; Schäfer-Nameki, Sakura

    2018-06-01

    We continue to develop the program initiated in [1] of studying supersymmetric AdS3 backgrounds of F-theory and their holographic dual 2d superconformal field theories, which are dimensional reductions of theories with varying coupling. Imposing 2d N=(0,2) supersymmetry,wederivethegeneralconditionsonthegeometryforTypeIIB AdS3 solutions with varying axio-dilaton and five-form flux. Locally the compact part of spacetime takes the form of a circle fibration over an eight-fold Y_8^{τ } , which is elliptically fibered over a base \\tilde{M}_6 . We construct two classes of solutions given in terms of a product ansatz \\tilde{M}_6}=Σ × {M}_4 , where Σ is a complex curve and \\tilde{M}_4 is locally a Kähler surface. In the first class \\tilde{M}_4 is globally a Kähler surface and we take the elliptic fibration to vary non-trivially over either of these two factors, where in both cases the metrics on the total space of the elliptic fibrations are not Ricci-flat. In the second class the metric on the total space of the elliptic fibration over either curve or surface are Ricci-flat. This results in solutions of the type AdS3 × K3 × ℳ 5 τ , dual to 2d (0, 2) SCFTs, and AdS3 × S 3/Γ × CY 3, dual to 2d (0, 4) SCFTs, respectively. In all cases we compute the charges for the dual field theories with varying coupling and find agreement with the holographic results. We also show that solutions with enhanced 2d N=(2,2) supersymmetry must have constant axio-dilaton. Allowing the internal geometry to be non-compact leads to the most general class of Type IIB AdS5 solutions with varying axio-dilaton, i.e. F-theoretic solutions, that are dual to 4d N=1 SCFTs.

  20. Development of compact toroids injector for direct plasma controls

    Energy Technology Data Exchange (ETDEWEB)

    Azuma, K. [Mitsubishi Heavy Industries Ltd., Takasago (Japan); Oda, Y. [Mitsubishi Heavy Industries Ltd., Takasago (Japan); Onozuka, M. [Mitsubishi Heavy Industries Ltd., Takasago (Japan); Uyama, T. [Himeji Inst. of Tech. (Japan); Nagata, M. [Himeji Inst. of Tech. (Japan); Fukumoto, N. [Himeji Inst. of Tech. (Japan)

    1995-12-31

    The application of the compact toroids injector for direct plasma controls has been investigated. The compact toroids injection can fuel particles directly into the core of the plasma and modify the plasma profiles at the desired locations. The acceleration tests of the compact toroids have been conducted at Himeji Institute of Technology. The tests showed that the hydrogen compact toroid was accelerated up to 80km/s and the plasma density of the compact toroid was compressed to 1.2 x 10{sup 21}m{sup -3}. (orig.).

  1. The design, development and operation of a compact nuclear power plant simulator

    International Nuclear Information System (INIS)

    Lynch, M.F.

    1987-01-01

    This paper discusses the philosophy and technological considerations necessary for constructing and utilizing a plant specific compact nuclear power plant simulator, how it compares to full scope replica simulators, engineering simulators, part task simulators and basic principles training simulators. Included in this discussion are the design process, scope of simulation, the manufacturing process, test programs and experiences with operator training. Items addressed include the applicability and use of a compact simulator, how well it reproduces the actual reference plant, how well the transferral of knowledge is accomplished and what financial considerations need to be evaluated. This paper tries to provide the details on just how this type of machine was designed and developed by Westinghouse for the Swiss Utility, Nordostschweizerische Kraftwerke (NOK) AG

  2. Acceleration of a compact torus

    International Nuclear Information System (INIS)

    Hartmann, C.W.; Eddleman, J.L.; Hammer, J.H.; Kusse, B.

    1987-01-01

    The authors report the first results of a study of acceleration of spheromak-type compact toruses in the RACE experiment (plasma Ring ACceleration Experiment). The RACE apparatus consists of (1) a magnetized, coaxial plasma gun 50 cm long, 35 cm OD, 20 cm ID, (2) 600 cm long coaxial acceleration electrodes 50 cm OD, 20 cm ID, (3) a 250 kJ electrolytic capacitor bank to drive the gun solenoid for initial magnetization, (4) a 200 kJ gun bank, (5) a 260 kJ accelerator bank, and (6) magnetic probes and other diagnostics, and vacuum apparatus. To outer acceleration electrode is an extension, at larger OD, of the gun outer electrode, and the inner acceleration electrode is supported and fed by a coaxial insert in the gun center electrode as shown

  3. Development of the compaction machine for the production of new shapes of pressed biofuels

    Science.gov (United States)

    Šooš, Ľubomír; Matúš, Miloš; Beniak, Juraj; Križan, Peter

    2018-01-01

    Briquettes and especially pellets became the fuel of the 21st century. These are pressed biofuels made from the biomass which have the required heat, shape, size, density and mechanical properties. Today, these pressed biofuels are made in the form of a block, cylinder, n-angle octagonal, either without or with the holes. Several analyses confirm that neither a block, nor the cylinder is the optimal shape for the production of pressed biofuels, both in terms of the production, storage, automated transport in the combustion process and the optimum combustion process. For this reason, we began to analyse different shape, size, density and mechanical properties of briquettes and pellets. In the first part of this article, the biofuel is described from these points of view. The result of this analysis is the new optimized spheroid shape of the pressed biofuels. The goal of the second part of the article is the construction design of a new compacting machine for manufacturing of the optimized shape of the compacted piece. The task is demanding due to the fact that in comparison to the production of cylindrical or square-shaped compacted pieces, the manufacturing of ‘quasi-spherical’ compacted pieces is discontinuous. Furthermore, unlike the standard types of compaction presses which compact the material between the two cylinders, it is necessary to hold the compacted piece for certain time under high pressure and at the high temperature. In this way, the lignin contained in compacted raw material becomes plastic and no further binding material needs to be added. The kinematics of a new compactor was therefore divided into two stages- ‘the stage of compacting’ and ‘the stage of load bearing capacity. This article describes an innovative and patent protected principle of compactor construction. The prototype of a designed machine has already been produced in our department. The first test results of this machine production as described in the conclusion of the

  4. Soil properties and aspen development five years after compaction and forest floor removal

    Science.gov (United States)

    Douglas M. Stone; John D. Elioff

    1998-01-01

    Forest management activities that decrease soil porosity and remove organic matter have been associated with declines in site productivity. In the northern Lake States region, research is in progress in the aspen (Populus tremuloides Michx. and P. grandidentata Michx.) forest type to determine effects of soil compaction and organic...

  5. Compact radio sources

    International Nuclear Information System (INIS)

    Altschuler, D.R.

    1975-01-01

    Eighty-seven compact radio sources were monitored between 1971 and 1974 with the National Radio Astronomy Observatory interferometer. Both flux density and polarization were measured at intervals of about one month at wavelengths of 3.7 and 11.1 cms. Forty-four sources showed definite variability in their total and/or polarized flux density. The variations in polarization were of a shorter time scale than the corresponding flux density variations. Some of the qualitative features of an expanding source model were observed. The data suggest that some form of injection of relativistic electrons is taking place. The absence of significant depolarization in the variable sources indicates that only a small fraction of the mass of the radio outburst is in the form of non-relativistic plasma. Some of the objects observed belong to the BL-Lacertal class. It is shown that this class is very inhomogeneous in its radio properties. For the violently variable BL-Lacertal type objects the spectrum, flux variations and polarization data strongly suggest that these are very young objects

  6. Principles of control automation of soil compacting machine operating mechanism

    Science.gov (United States)

    Anatoly Fedorovich, Tikhonov; Drozdov, Anatoly

    2018-03-01

    The relevance of the qualitative compaction of soil bases in the erection of embankment and foundations in building and structure construction is given.The quality of the compactible gravel and sandy soils provides the bearing capability and, accordingly, the strength and durability of constructed buildings.It has been established that the compaction quality depends on many external actions, such as surface roughness and soil moisture; granulometry, chemical composition and degree of elasticity of originalfilled soil for compaction.The analysis of technological processes of soil bases compaction of foreign and domestic information sources showed that the solution of such important problem as a continuous monitoring of soil compaction actual degree in the process of machine operation carry out only with the use of modern means of automation. An effective vibrodynamic method of gravel and sand material sealing for the building structure foundations for various applications was justified and suggested.The method of continuous monitoring the soil compaction by measurement of the amplitudes and frequencies of harmonic oscillations on the compactible surface was determined, which allowed to determine the basic elements of facilities of soil compacting machine monitoring system of operating, etc. mechanisms: an accelerometer, a bandpass filter, a vibro-harmonics, an on-board microcontroller. Adjustable parameters have been established to improve the soil compaction degree and the soil compacting machine performance, and the adjustable parameter dependences on the overall indexhave been experimentally determined, which is the soil compaction degree.A structural scheme of automatic control of the soil compacting machine control mechanism and theoperation algorithm has been developed.

  7. FEM modeling on the compaction of Fe and Al composite powders

    Directory of Open Access Journals (Sweden)

    Han P.

    2015-01-01

    Full Text Available The compaction process of Fe and Al composite powders subjected to single action die compaction was numerically modeled by FEM method. The relationship between the overall relative density and compaction pressure of the compacts with various Al contents was firstly identified, and the influences of Al content on the local relative density, stress, and their distributions were studied. Then the compaction pressure effects on the above properties with fixed Al content were discussed. Furthermore, detailed flow behaviors of the composite powders during compaction and the relationship between the compaction pressure and the ejection force/spring back of the compact were analyzed. The results show that: (1 With each compaction pressure, higher relative density can be realized with the increase of Al content and the relative density distribution tends to be uniform; (2 When the Al content is fixed, higher compaction pressure can lead to composite compact with higher relative density, and the equivalent Von Mises stress in the central part of the compact increases gradually; (3 Convective flow occurs at the top and bottom parts of the compact close to the die wall, each indicates a different flow behavior; (4 The larger the compaction pressure for each case, the higher the residual elasticity, and the larger the ejection force needed.

  8. Radioactive spent resins conditioning by the hot super-compaction process

    International Nuclear Information System (INIS)

    Roth, Andreas; Centner, Baudouin; Lemmens, Alain

    2007-01-01

    Spent ion exchanger media are considered to be problematic waste that, in many cases, requires special approaches and precautions during its immobilization to meet the acceptance criteria for disposal. The waste acceptance criteria define, among others, the quality of waste forms for disposal, and therefore will sometimes define appropriate treatment options. The selection of treatment options for spent ion exchange materials must consider their physical and chemical characteristics. Basically, the main methods for the treatment of spent organic ion exchange materials, following to pretreatment methods are: - Direct immobilization, producing a stable end product by using Cement, Bitumen, Polymer or High Integrity Containers, - The destruction of the organic compounds by using Thermochemical processes or Oxidation to produce an inorganic intermediate product that may or may not be further conditioned for storage and/or disposal, - The complete removal of the resin inner structural water by a thermal process. After a thorough technical economical analysis, Tractebel Engineering selected the Resin Hot Compaction Process to be installed at Tihange Nuclear Power Plant. The Resin Hot Compaction Process is used to make dense homogenous organic blocks from a wide range of particulate waste. In this process spent resins are first dewatered and dried to remove the inner structural water content. The drying takes place in a drying vessel that holds the contents of two 200 L drums (Figure). In the oil heated drying and mixing unit, the resins are heated to the necessary process temperature for the hot pressing step and then placed into special metal drums, which are automatically lidded and immediately transferred to a high force compactor. After high force compaction the pellets are transferred to a measuring unit, where the dose rate, height and weight are automatically measured and recorded. A volume reduction factor of approximately up to four (depending on the type of

  9. Mechanical and chemical compaction in fine-grained shallow-water limestones.

    Science.gov (United States)

    Shinn, E.A.; Robbin, D.M.

    1983-01-01

    Significant mechanical compaction resulted from pressures simulating less than 305 m of burial. Increasing loads to an equivalent of more than 3400 m did not significantly increase compaction or reduce sediment core length. Chemical compaction (pressure dissolution) was detected only in sediment cores compacted to pressures greater than 3400 m of burial. These short-term experiments suggest that chemical compaction would begin at much shallower depths given geologic time. Compaction experiments that caused chemical compaction lend support to the well-established hypothesis; that cement required to produce a low-porosity/low-permeability fine-grained limestone is derived internally. Dissolution, ion diffusion, and reprecipitation are considered the most likely processes for creating significant thicknesses of dense limestone in the geologic record. Continuation of chemical compaction after significant porosity reduction necessitates expulsion of connate fluids, possibly including hydrocarbons. -from Authors

  10. Bone compaction enhances implant fixation in a canine gap model

    DEFF Research Database (Denmark)

    Kold, Søren; Rahbek, Ole; Toft, Marianne

    2005-01-01

    A new bone preparation technique, compaction, has increased fixation of implants inserted with exact-fit or press-fit to bone. Furthermore, a demonstrated spring-back effect of compacted bone might be of potential value in reducing the initial gaps that often exist between clinical inserted...... implants and bone. However, it is unknown whether the compression and breakage of trabeculae during the compaction procedure results in impaired gap-healing of compacted bone. Therefore, we compared compaction with conventional drilling in a canine gap model. Grit-blasted titanium implants (diameter 6 mm...... that the beneficial effect of reduced gap size, as compacted bone springs back, is not eliminated by an impaired gap-healing of compacted bone....

  11. Modeling compaction-induced energy dissipation of granular HMX

    Energy Technology Data Exchange (ETDEWEB)

    Gonthier, K.A. [Lamar Univ., Beaumont, TX (US). Dept. of Mechanical Engineering; Menikoff, R.; Son, S.F.; Asay, B.W. [Los Alamos National Lab., NM (US)

    1998-12-31

    A thermodynamically consistent model is developed for the compaction of granular solids. The model is an extension of the single phase limit of two-phase continuum models used to describe Deflagration-to-Detonation Transition (DDT) experiments. The focus is on the energetics and dissipation of the compaction process. Changes in volume fraction are partitioned into reversible and irreversible components. Unlike conventional DDT models, the model is applicable from the quasi-static to dynamic compaction regimes for elastic, plastic, or brittle materials. When applied to the compaction of granular HMX (a brittle material), the model predicts results commensurate with experiments including stress relaxation, hysteresis, and energy dissipation. The model provides a suitable starting point for the development of thermal energy localization sub-scale models based on compaction-induced dissipation.

  12. Strategy Guideline. Compact Air Distribution Systems

    Energy Technology Data Exchange (ETDEWEB)

    Burdick, Arlan [IBACOS, Inc., Pittsburgh, PA (United States)

    2013-06-01

    This guideline discusses the benefits and challenges of using a compact air distribution system to handle the reduced loads and reduced air volume needed to condition the space within an energy efficient home. The decision criteria for a compact air distribution system must be determined early in the whole-house design process, considering both supply and return air design. However, careful installation of a compact air distribution system can result in lower material costs from smaller equipment, shorter duct runs, and fewer outlets; increased installation efficiencies, including ease of fitting the system into conditioned space; lower loads on a better balanced HVAC system, and overall improved energy efficiency of the home.

  13. The use of compaction in the manufacture of tablets

    Directory of Open Access Journals (Sweden)

    O. V. Tryhubchak

    2016-08-01

    Full Text Available In the production of tablets direct compression method, wet and dry granulationare used. Dry granulation can be used if materials have sufficient cohesive properties to form granules. Scientific publications of recent years clearly demonstrate the prospects of roller compaction using in pharmaceutical industry. Aim. The aim of work is to generalize available data regarding to the use of compaction in the pharmaceutical industry. Materials and methods. We have studied and analyzed the available scientific sources in order to generalize the available literature on the use of compacting in the production of the tablets. During this study we used methods of observation and systematization analysis. Results. Materials for compaction characteristics of the process, its benefits and conditions of application have been collected and systematized, parameters of process have been selected, theories of compaction have been generalized, the characteristics and examples of compaction equipment have been adduced, and the key characteristics of the material used in the pharmaceutical industry have been demonstrated. Compacting is dry granulation technology in which powder containing active ingredients and excipients are compacted between two opposing spinning rollers by applying mechanical pressure. Compared with the original powder, granules after compression are characterized by much better fluidity and higher density by reducing the volume. The roller consolidation process substantially affects the particle size distribution, flowability, homogeneity, pressing, compaction substances and excipients, therefore, can affect dissolution, time of disintegration, resistance to crushing, abrasion of tablets. The main parameters of compacting are seal and method of its application, conditions and speed of the process. Conclusions. It has been established that the use of compacting decreases or increases particles size to form granules, which leads to improved

  14. Land subsidence and hydrodynamic compaction of sedimentary basins

    Directory of Open Access Journals (Sweden)

    H. Kooi

    1998-01-01

    Full Text Available A one-dimensional model is used to investigate the relationship between land subsidence and compaction of basin sediments in response to sediment loading. Analysis of the model equations and numerical experiments demonstrate quasi-linear systems behaviour and show that rates of land subsidence due to compaction: (i can attain a significant fraction (>40% of the long-term sedimentation rate; (ii are hydrodynamically delayed with respect to sediment loading. The delay is controlled by a compaction response time τc that can reach values of 10-5-107 yr for thick shale sequences. Both the behaviour of single sediment layers and multiple-layer systems are analysed. Subsequently the model is applied to the coastal area of the Netherlands to illustrate that lateral variability in compaction-derived land subsidence in sedimentary basins largely reflects the spatial variability in both sediment loading and compaction response time. Typical rates of compaction-derived subsidence predicted by the model are of the order of 0.1 mm/yr but may reach values in excess of 1 mm/yr under favourable conditions.

  15. DNA compaction by azobenzene-containing surfactant

    International Nuclear Information System (INIS)

    Zakrevskyy, Yuriy; Kopyshev, Alexey; Lomadze, Nino; Santer, Svetlana; Morozova, Elena; Lysyakova, Ludmila; Kasyanenko, Nina

    2011-01-01

    We report on the interaction of cationic azobenzene-containing surfactant with DNA investigated by absorption and fluorescence spectroscopy, dynamic light scattering, and atomic force microscopy. The properties of the surfactant can be controlled with light by reversible switching of the azobenzene unit, incorporated into the surfactant tail, between a hydrophobic trans (visible irradiation) and a hydrophilic cis (UV irradiation) configuration. The influence of the trans-cis isomerization of the azobenzene on the compaction process of DNA molecules and the role of both isomers in the formation and colloidal stability of DNA-surfactant complexes is discussed. It is shown that the trans isomer plays a major role in the DNA compaction process. The influence of the cis isomer on the DNA coil configuration is rather small. The construction of a phase diagram of the DNA concentration versus surfactant/DNA charge ratio allows distancing between three major phases: colloidally stable and unstable compacted globules, and extended coil conformation. There is a critical concentration of DNA above which the compacted globules can be hindered from aggregation and precipitation by adding an appropriate amount of the surfactant in the trans configuration. This is because of the compensation of hydrophobicity of the globules with an increasing amount of the surfactant. Below the critical DNA concentration, the compacted globules are colloidally stable and can be reversibly transferred with light to an extended coil state.

  16. Compact torsatron reactors

    International Nuclear Information System (INIS)

    Lyon, J.F.; Carreras, B.A.; Lynch, V.E.; Tolliver, J.S.; Sviatoslavsky, I.N.

    1988-05-01

    Low-aspect-ratio torsatron configurations could lead to compact stellarator reactors with R 0 = 8--11m, roughly one-half to one-third the size of more conventional stellarator reactor designs. Minimum-size torsatron reactors are found using various assumptions. Their size is relatively insensitive to the choice of the conductor parameters and depends mostly on geometrical constraints. The smallest size is obtained by eliminating the tritium breeding blanket under the helical winding on the inboard side and by reducing the radial depth of the superconducting coil. Engineering design issues and reactor performance are examined for three examples to illustrate the feasibility of this approach for compact reactors and for a medium-size (R 0 ≅ 4 m,/bar a/ /approx lt/ 1 m) copper-coil ignition experiment. 26 refs., 11 figs., 7 tabs

  17. Compact fusion reactors

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    Fusion research is currently to a large extent focused on tokamak (ITER) and inertial confinement (NIF) research. In addition to these large international or national efforts there are private companies performing fusion research using much smaller devices than ITER or NIF. The attempt to achieve fusion energy production through relatively small and compact devices compared to tokamaks decreases the costs and building time of the reactors and this has allowed some private companies to enter the field, like EMC2, General Fusion, Helion Energy, Lawrenceville Plasma Physics and Lockheed Martin. Some of these companies are trying to demonstrate net energy production within the next few years. If they are successful their next step is to attempt to commercialize their technology. In this presentation an overview of compact fusion reactor concepts is given.

  18. Surface area of lactose and lactose granulates on consolidation and compaction

    OpenAIRE

    Riepma, Klaas Alouis

    1993-01-01

    This dissertation discusses the effect of short time storage at different conditions on the strength and the specific BET surface area of lactose tablets. In addition, some aspects are studied of the consolidation and compaction properties of crystalline lactose fractions in heterogeneous systems. The crystalline lactose types used are: a-lactose monohydrate, anhydrous a-lactose, crystalline B-lactose and roller dried B-lactose. ... Zie: Summary

  19. Large-volume static compression using nano-polycrystalline diamond for opposed anvils in compact cells

    International Nuclear Information System (INIS)

    Okuchi, T; Sasaki, S; Ohno, Y; Osakabe, T; Odake, S; Kagi, H

    2010-01-01

    In order to extend the pressure regime of intrinsically low-sensitivity methods of measurement, such as neutron scattering and NMR, sample volume to be compressed in compact opposed-anvil cells is desired to be significantly increased. We hereby conducted a series of experiments using two types of compact cells equipped with enforced loading mechanisms. Super-hard nano-polycrystalline diamond (NPD) anvils were carefully prepared for large-volume compression in these cells. These anvils are harder, larger and stronger than single crystal diamond anvils, so that they could play an ideal role to accept the larger forces. Supported and unsupported anvil geometries were separately tested to evaluate this expectation. In spite of insufficient support to the anvils, pressures to 14 GPa were generated for the sample volume of > 0.1 mm 3 , without damaging the NPD anvils. These results demonstrate a large future potential of compact cells equipped with NPD anvils and enforced loading mechanism.

  20. On compact multipliers of topological algebras

    International Nuclear Information System (INIS)

    Mohammad, N.

    1994-08-01

    It is shown that if the maximal ideal space Δ(A) of a semisimple commutative complete metrizable locally convex algebra contains no isolated points, then every compact multiplier is trivial. Particularly, compact multipliers on semisimple commutative Frechet algebras whose maximal ideal space has no isolated points are identically zero. (author). 5 refs

  1. The classification of 2-compact groups

    DEFF Research Database (Denmark)

    K. S. Andersen, Kasper; Grodal, Jesper

    2009-01-01

    with Moeller and Viruel for p odd, this establishes the full classification of p-compact groups, stating that, up to isomorphism, there is a one-to-one correspondence between connected p-compact groups and root data over the p-adic integers. As a consequence we prove the maximal torus conjecture, giving a one...

  2. A new compact fixed-point blackbody furnace

    International Nuclear Information System (INIS)

    Hiraka, K.; Oikawa, H.; Shimizu, T.; Kadoya, S.; Kobayashi, T.; Yamada, Y.; Ishii, J.

    2013-01-01

    More and more NMIs are realizing their primary scale themselves with fixed-point blackbodies as their reference standard. However, commercially available fixed-point blackbody furnaces of sufficient quality are not always easy to obtain. CHINO Corp. and NMIJ, AIST jointly developed a new compact fixed-point blackbody furnace. The new furnace has such features as 1) improved temperature uniformity when compared to previous products, enabling better plateau quality, 2) adoption of the hybrid fixed-point cell structure with internal insulation to improve robustness and thereby to extend lifetime, 3) easily ejectable and replaceable heater unit and fixed-point cell design, leading to reduced maintenance cost, 4) interchangeability among multiple fixed points from In to Cu points. The replaceable cell feature facilitates long term maintenance of the scale through management of a group of fixed-point cells of the same type. The compact furnace is easily transportable and therefore can also function as a traveling standard for disseminating the radiation temperature scale, and for maintaining the scale at the secondary level and industrial calibration laboratories. It is expected that the furnace will play a key role of the traveling standard in the anticipated APMP supplementary comparison of the radiation thermometry scale

  3. Shielding design to obtain compact marine reactor

    International Nuclear Information System (INIS)

    Yamaji, Akio; Sako, Kiyoshi

    1994-01-01

    The marine reactors equipped in previously constructed nuclear ships are in need of the secondary shield which is installed outside the containment vessel. Most of the weight and volume of the reactor plants are occupied by this secondary shield. An advanced marine reactor called MRX (Marine Reactor X) has been designed to obtain a more compact and lightweight marine reactor with enhanced safety. The MRX is a new type of marine reactor which is an integral PWR (The steam generator is installed in the pressure vessel.) with adopting a water-filled containment vessel and a new shielding design method of no installation of the secondary shield. As a result, MRX is considerably lighter in weight and more compact in size as compared with the reactors equipped in previously constructed nuclear ships. For instance, the plant weight and volume of the containment vessel of MRX are about 50% and 70% of those of the Nuclear Ship MUTSU, in spite of the power of MRX is 2.8 times as large as the MUTSU's reactor. The shielding design calculation was made using the ANISN, DOT3.5, QAD-CGGP2 and ORIGEN codes. The computational accuracy was confirmed by experimental analyses. (author)

  4. Ultra high frequency induction welding of powder metal compacts

    Energy Technology Data Exchange (ETDEWEB)

    Cavdar, U.; Gulsahin, I.

    2014-10-01

    The application of the iron based Powder Metal (PM) compacts in Ultra High Frequency Induction Welding (UHFIW) were reviewed. These PM compacts are used to produce cogs. This study investigates the methods of joining PM materials enforceability with UHFIW in the industry application. Maximum stress and maximum strain of welded PM compacts were determined by three point bending and strength tests. Microhardness and microstructure of induction welded compacts were determined. (Author)

  5. Ultra high frequency induction welding of powder metal compacts

    International Nuclear Information System (INIS)

    Cavdar, U.; Gulsahin, I.

    2014-01-01

    The application of the iron based Powder Metal (PM) compacts in Ultra High Frequency Induction Welding (UHFIW) were reviewed. These PM compacts are used to produce cogs. This study investigates the methods of joining PM materials enforceability with UHFIW in the industry application. Maximum stress and maximum strain of welded PM compacts were determined by three point bending and strength tests. Microhardness and microstructure of induction welded compacts were determined. (Author)

  6. The etching behaviour of silicon carbide compacts

    International Nuclear Information System (INIS)

    Jepps, N.W.; Page, T.F.

    1981-01-01

    A series of microstructural investigations has been undertaken in order to explore the reliability of particular etches in revealing microstructural detail in silicon carbide compacts. A series of specimens has been etched and examined following complete prior microstructural characterization by transmission electron microscopy (TEM), scanning electron microscopy (SEM) and X-ray diffractometry techniques. In particular, the sensitivity of both a molten salt (KOH/KNO 3 ) etch and a commonly-used oxidizing electrolytic 'colour' etch to crystal purity, crystallographic orientation and polytypic structure has been established. The molten salt etch was found to be sensitive to grain boundaries and stacking disorder while the electrolytic etch was found to be primarily sensitive to local purity and crystallographic orientation. Neither etch appeared intrinsically polytype sensitive. Specifically, for the 'colour' etch, the p- or n-type character of impure regions appears critical in controlling etching behaviour; p-type impurities inhibiting, and n-type impurities enhancing, oxidation. The need to interpret etching behaviour in a manner consistent with the results obtained by a variety of other microstructural techniques will be emphasized. (author)

  7. Automatic test equipment for C and I of compact LWR

    International Nuclear Information System (INIS)

    Mayya, Anuradha; Marathe, P.P.; Madala, Kalyan C.

    2014-01-01

    The C and I of compact LWR consist of a wide variety of electronic modules. Testing of these modules manually was found to be very cumbersome. To ease the testing of these modules, Automatic Test Equipments (ATE) were developed jointly by BARC and ECIL. This paper describes the design of two ATEs for testing 69 types of modules. A power supply ATE was developed for 43 types of power supply modules of type AC-AC, AC-DC, DC-DC and signal conditioning modules. A VME ATE was developed to test 26 types of VME bus based and other microcontroller based non-bussed modules. These ATEs are used for the automated black box testing of modules by feeding power and control inputs and checking the outputs without operator intervention. This paper describes the important considerations in design and the major design challenges. (author)

  8. Compaction of an Oxisol and chemical composition of palisadegrass

    Directory of Open Access Journals (Sweden)

    Eurico Lucas de Sousa Neto

    2013-08-01

    Full Text Available Compaction is an important problem in soils under pastoral land use, and can make livestock systems unsustainable. The objective of this research was to study the impact of soil compaction on yield and quality of palisade (UROCHLOA BRIZANTHA cv. Marandu. The experiment was conducted on an Oxisol in the State of Mato Grosso, Brazil. Treatments consisted of four levels of soil compaction: no compaction (NC, slight compaction (SC, medium compaction (MC and high compaction (HC. The following soil properties were evaluated (layers 0-0.05 and 0.05-0.10 m: aggregate size distribution, bulk density (BD, macroporosity, microporosity, total porosity (TP, relative compaction (RC, and the characteristics of crude protein (CP, neutral detergent fiber (NDF, acid detergent fiber (ADF and dry matter yield (DMY of the forage. Highly compacted soil had high BD and RC, and low TP (0-0.05 m. Both DMY and CP were affected by HC, and both were strongly related to BD. Higher DMY (6.96 Mg ha-1 and CP (7.8 % were observed in the MC treatment (BD 1.57 Mg m-3 and RC 0.91 Mg m-3, in 0-0.05 m. A high BD of 1.57 Mg m-3 (0-0.05 m did not inhibit plant growth. The N concentration in the palisade biomass differed significantly among compaction treatments, and was 8.72, 11.20, 12.48 and 10.98 g kg-1 in NC, SC, MC and HC treatments, respectively. Increase in DMY and CP at the MC level may be attributed to more absorption of N in this coarse-textured soil.

  9. Explaining compact groups as change alignments

    International Nuclear Information System (INIS)

    Mamon, G.A.

    1990-01-01

    The physical nature of the apparently densest groups of galaxies, known as compact groups is a topic of some recent controversy, despite the detailed observations of a well-defined catalog of 100 isolated compact groups compiled by Hickson (1982). Whereas many authors have espoused the view that compact groups are bound systems, typically as dense as they appear in projection on the sky (e.g., Williams ampersand Rood 1987; Sulentic 1987; Hickson ampersand Rood 1988), others see them as the result of chance configurations within larger systems, either in 1D (chance alignments: Mamon 1986; Walke ampersand Mamon 1989), or in 3D (transient cores: Rose 1979). As outlined in the companion review to this contribution (Mamon, in these proceedings), the implication of Hickson's compact groups (HCGs) being dense bound systems is that they would then constitute the densest isolated systems of galaxies in the Universe and the privileged site for galaxy interactions. In a previous paper (Mamon 1986), the author reviewed the arguments given for the different theories of compact groups. Since then, a dozen papers have been published on the subject, including a thorough and perceptive review by White (1990), thus more than doubling the amount written on the subject. Here, the author first enumerates the arguments that he brought up in 1986 substantiating the chance alignment hypothesis, then he reviews the current status of the numerous recent arguments arguing against chance alignments and/or for the bound dense group hypothesis (both for the majority of HCGs but not all of them), and finally he reconsiders each one of these anti-chance alignment arguments and shows that, rather than being discredited, the chance alignment hypothesis remains a fully consistent explanation for the nature of compact groups

  10. Analysis of the cold compaction behaviour of TiH2-316L nanocomposite powder blend using compaction models

    CSIR Research Space (South Africa)

    Machio, Christopher N

    2015-07-01

    Full Text Available The paper captures the effect of structure and the applicability of compaction models using the cold compaction of a TiH2-SS316L composite powder prepared by high energy mechanical milling. The composite blend was cold pressed uniaxially...

  11. Compact wire array sources: power scaling and implosion physics.

    Energy Technology Data Exchange (ETDEWEB)

    Serrano, Jason Dimitri; Chuvatin, Alexander S. (Laboratoire du Centre National de la Recherche Scientifique Ecole Polytechnique, Palaiseau, France); Jones, M. C.; Vesey, Roger Alan; Waisman, Eduardo M.; Ivanov, V. V. (University of Nevada - Reno, Reno, NV); Esaulov, Andrey A. (University of Nevada - Reno, Reno, NV); Ampleford, David J.; Cuneo, Michael Edward; Kantsyrev, Victor Leonidovich (University of Nevada - Reno, Reno, NV); Coverdale, Christine Anne; Rudakov, L. I. (Icarus Research, Bethesda, MD); Jones, Brent Manley; Safronova, Alla S. (University of Nevada - Reno, Reno, NV); Vigil, Marcelino Patricio

    2008-09-01

    A series of ten shots were performed on the Saturn generator in short pulse mode in order to study planar and small-diameter cylindrical tungsten wire arrays at {approx}5 MA current levels and 50-60 ns implosion times as candidates for compact z-pinch radiation sources. A new vacuum hohlraum configuration has been proposed in which multiple z pinches are driven in parallel by a pulsed power generator. Each pinch resides in a separate return current cage, serving also as a primary hohlraum. A collection of such radiation sources surround a compact secondary hohlraum, which may potentially provide an attractive Planckian radiation source or house an inertial confinement fusion fuel capsule. Prior to studying this concept experimentally or numerically, advanced compact wire array loads must be developed and their scaling behavior understood. The 2008 Saturn planar array experiments extend the data set presented in Ref. [1], which studied planar arrays at {approx}3 MA, 100 ns in Saturn long pulse mode. Planar wire array power and yield scaling studies now include current levels directly applicable to multi-pinch experiments that could be performed on the 25 MA Z machine. A maximum total x-ray power of 15 TW (250 kJ in the main pulse, 330 kJ total yield) was observed with a 12-mm-wide planar array at 5.3 MA, 52 ns. The full data set indicates power scaling that is sub-quadratic with load current, while total and main pulse yields are closer to quadratic; these trends are similar to observations of compact cylindrical tungsten arrays on Z. We continue the investigation of energy coupling in these short pulse Saturn experiments using zero-dimensional-type implosion modeling and pinhole imaging, indicating 16 cm/?s implosion velocity in a 12-mm-wide array. The same phenomena of significant trailing mass and evidence for resistive heating are observed at 5 MA as at 3 MA. 17 kJ of Al K-shell radiation was obtained in one Al planar array fielded at 5.5 MA, 57 ns and we

  12. Automorphisms of p-compact groups and their root data

    DEFF Research Database (Denmark)

    Andersen, Kasper K. S.; Grodal, Jesper Kragh

    2008-01-01

    We construct a model for the space of automorphisms of a connected p–compact group in terms of the space of automorphisms of its maximal torus normalizer and its root datum. As a consequence we show that any homomorphism to the outer automorphism group of a p–compact group can be lifted to a group...... action, analogous to   a classical theorem of de Siebenthal for compact Lie groups. The model of this paper is used in a crucial way in our paper `The classification of 2-compact groups' [arXiv:math.AT/0611437], where we prove the conjectured classification of 2–compact groups and determine...... their automorphism spaces....

  13. Aspects of type $0$ string theory

    CERN Document Server

    Blumenhagen, R; Kumar, A; Lüst, Dieter

    2000-01-01

    A construction of compact tachyon-free orientifolds of the non-supersymmetric Type 0B string theory is presented. Moreover, we study effective non-supersymmetric gauge theories arising on self-dual D3-branes in Type 0B orbifolds and orientifolds.

  14. Application of an antenna excited high pressure microwave discharge to compact discharge lamps

    International Nuclear Information System (INIS)

    Kando, M; Fukaya, T; Ohishi, Y; Mizojiri, T; Morimoto, Y; Shido, M; Serita, T

    2008-01-01

    A novel type of high pressure microwave discharge has been investigated to feed the microwave power at the centre of the compact high pressure discharge lamps using the antenna effect. This method of microwave discharge is named as the antenna excited microwave discharge (AEMD). The 2.45 GHz microwave of around 50 W from the solid state microwave generator can sustain a stable plasma column in the small gap between a couple of antennas fitted on the compact lamp filled with discharge gases at a pressure higher than atmosphere. The AEMD has been applied to a compact metal halide lamp and an extremely high pressure mercury discharge lamp. As a result, the metal halide lamp showed high luminous efficacy of around 130 lm W -1 . The excellent lamp properties obtained here can be explained by the low heating loss at the antennas and the lamp wall. The profiles of the microwave electric field in the lamp and the microwave launcher have been numerically calculated to consider the microwave power supply into the lamp

  15. Deficiencies in both starch synthase IIIa and branching enzyme IIb lead to a significant increase in amylose in SSIIa-inactive japonica rice seeds.

    Science.gov (United States)

    Asai, Hiroki; Abe, Natsuko; Matsushima, Ryo; Crofts, Naoko; Oitome, Naoko F; Nakamura, Yasunori; Fujita, Naoko

    2014-10-01

    Starch synthase (SS) IIIa has the second highest activity of the total soluble SS activity in developing rice endosperm. Branching enzyme (BE) IIb is the major BE isozyme, and is strongly expressed in developing rice endosperm. A mutant (ss3a/be2b) was generated from wild-type japonica rice which lacks SSIIa activity. The seed weight of ss3a/be2b was 74-94% of that of the wild type, whereas the be2b seed weight was 59-73% of that of the wild type. There were significantly fewer amylopectin short chains [degree of polymerization (DP) ≤13] in ss3a/be2b compared with the wild type. In contrast, the amount of long chains (DP ≥25) connecting clusters of amylopectin in ss3a/be2b was higher than in the wild type and lower than in be2b. The apparent amylose content of ss3a/be2b was 45%, which was >1.5 times greater than that of either ss3a or be2b. Both SSIIIa and BEIIb deficiencies led to higher activity of ADP-glucose pyrophosphorylase (AGPase) and granule-bound starch synthase I (GBSSI), which partly explains the high amylose content in the ss3a/be2b endosperm. The percentage apparent amylose content of ss3a and ss3a/be2b at 10 days after flowering (DAF) was higher than that of the wild type and be2b. At 20 DAF, amylopectin biosynthesis in be2b and ss3a/be2b was not observed, whereas amylose biosynthesis in these lines was accelerated at 30 DAF. These data suggest that the high amylose content in the ss3a/be2b mutant results from higher amylose biosynthesis at two stages, up to 20 DAF and from 30 DAF to maturity. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  16. An extended star formation history in an ultra-compact dwarf

    Science.gov (United States)

    Norris, Mark A.; Escudero, Carlos G.; Faifer, Favio R.; Kannappan, Sheila J.; Forte, Juan Carlos; van den Bosch, Remco C. E.

    2015-08-01

    There has been significant controversy over the mechanisms responsible for forming compact stellar systems like ultra-compact dwarfs (UCDs), with suggestions that UCDs are simply the high-mass extension of the globular cluster population, or alternatively, the liberated nuclei of galaxies tidally stripped by larger companions. Definitive examples of UCDs formed by either route have been difficult to find, with only a handful of persuasive examples of stripped-nucleus-type UCDs being known. In this paper, we present very deep Gemini/GMOS spectroscopic observations of the suspected stripped-nucleus UCD NGC 4546-UCD1 taken in good seeing conditions (noise spectrum to detect a temporally extended star formation history for this UCD. We find that the UCD was forming stars since the earliest epochs until at least 1-2 Gyr ago. Taken together these observations confirm that NGC 4546-UCD1 is the remnant nucleus of a nucleated dwarf galaxy that was tidally destroyed by NGC 4546 within the last 1-2 Gyr.

  17. Scintigraphic detection of acute experimental endocarditis with the technetium-99m labelled glycoprotein IIb/IIIa receptor antagonist DMP444

    Energy Technology Data Exchange (ETDEWEB)

    Oyen, W.J.G.; Boerman, O.C.; Corstens, F.H.M. [Department of Nuclear Medicine, University Hospital Nijmegen, Nijmegen (Netherlands); Brouwers, F.M. [Department of Nuclear Medicine, University Hospital Nijmegen, Nijmegen (Netherlands); Department of Internal Medicine, University Hospital Nijmegen, Nijmegen (Netherlands); Barrett, J.A. [DuPont Pharmaceutical Company, Radiopharmaceutical Division, North Billerica, MA (United States); Verheugt, F.W.A. [Department of Cardiology, University Hospital Nijmegen, Nijmegen (Netherlands); Ruiter, D.J. [Department of Pathology, University Hospital Nijmegen, Nijmegen (Netherlands); Meer, J.W.M. van der [Department of Internal Medicine, University Hospital Nijmegen, Nijmegen (Netherlands)

    2000-04-01

    Bacterial endocarditis is an important clinical problem that may result in persistent bacteraemia and irreversible cardiac damage. Since endocarditis is characterized by aggregation of activated platelets, fibrin and bacteria, we studied DMP444, a technetium-99m labelled high-affinity antagonist of the GP IIb/IIIa receptor that is expressed on activated platelets. In seven Beagle dogs (11-15 kg), the left ventricle was catheterized via the right carotid artery. One hour later, 5 x 10{sup 7} colony forming units of Staphylococcus aureus were injected intracardially. Half an hour later, the catheter was removed. Two extra dogs underwent a complete sham procedure. One day after the intervention, five infected and the two non-infected dogs were injected with 37 MBq/kg {sup 99m}Tc-DMP444 and two infected dogs with 37 MBq/kg {sup 99m}Tc-IgG (used as a non-specific control agent) and imaged up to 4 h after injection. Samples were obtained for tissue counting, microbiology and histology. From 1 to 2 h post injection onward, there was clear focal accumulation of DMP444 in the aortic valve region when endocarditis was present, and this accumulation increased with time. The non-infected and the {sup 99m}Tc-IgG injected dogs showed only persisting blood pool activity without any focal abnormality. At 4 h post injection, the in vivo valve-to-blood pool ratios were 1.87{+-}0.18 in endocarditis, 1.01{+-}0.05 in non-infected controls and 1.09{+-}0.02 in {sup 99m}Tc-IgG injected dogs (P<0.05). It is concluded that targeting activated platelets with the {sup 99m}Tc-labelled GP IIb/IIIa antagonist DMP444 allows a final diagnosis of experimental bacterial endocarditis within 4 h owing to high, specific and fast in vivo uptake. (orig.)

  18. Scintigraphic detection of acute experimental endocarditis with the technetium-99m labelled glycoprotein IIb/IIIa receptor antagonist DMP444

    International Nuclear Information System (INIS)

    Oyen, W.J.G.; Boerman, O.C.; Corstens, F.H.M.; Brouwers, F.M.; Barrett, J.A.; Verheugt, F.W.A.; Ruiter, D.J.; Meer, J.W.M. van der

    2000-01-01

    Bacterial endocarditis is an important clinical problem that may result in persistent bacteraemia and irreversible cardiac damage. Since endocarditis is characterized by aggregation of activated platelets, fibrin and bacteria, we studied DMP444, a technetium-99m labelled high-affinity antagonist of the GP IIb/IIIa receptor that is expressed on activated platelets. In seven Beagle dogs (11-15 kg), the left ventricle was catheterized via the right carotid artery. One hour later, 5 x 10 7 colony forming units of Staphylococcus aureus were injected intracardially. Half an hour later, the catheter was removed. Two extra dogs underwent a complete sham procedure. One day after the intervention, five infected and the two non-infected dogs were injected with 37 MBq/kg 99m Tc-DMP444 and two infected dogs with 37 MBq/kg 99m Tc-IgG (used as a non-specific control agent) and imaged up to 4 h after injection. Samples were obtained for tissue counting, microbiology and histology. From 1 to 2 h post injection onward, there was clear focal accumulation of DMP444 in the aortic valve region when endocarditis was present, and this accumulation increased with time. The non-infected and the 99m Tc-IgG injected dogs showed only persisting blood pool activity without any focal abnormality. At 4 h post injection, the in vivo valve-to-blood pool ratios were 1.87±0.18 in endocarditis, 1.01±0.05 in non-infected controls and 1.09±0.02 in 99m Tc-IgG injected dogs (P 99m Tc-labelled GP IIb/IIIa antagonist DMP444 allows a final diagnosis of experimental bacterial endocarditis within 4 h owing to high, specific and fast in vivo uptake. (orig.)

  19. Pharmaceutical powder compaction technology

    National Research Council Canada - National Science Library

    Çelik, Metin

    2011-01-01

    "Revised to reflect modern pharmaceutical compacting techniques, this Second Edition guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel...

  20. Evaluation of the shrinkage and creep of medium strength self compacting concrete

    Science.gov (United States)

    De La Cruz, C. J.; Ramos, G.; Hurtado, W. A.

    2017-02-01

    The difference between self compacting concrete (SCC) and conventional concrete (CC) is in fresh state, is the high fluidity at first and the need for vibration at second, but in hardened state, both concretes must comply with the resistance specified, in addition to securing the safety and functionality for which it was designed. This article describes the tests and results for shrinkage and creep at some medium strength Self Compacting Concrete with added sand (SCC-MSs) and two types of cement. The research was conducted at the Laboratorio de Tecnología de Estructuras (LTE) of the Universitat Politécnica de Catalunya (UPC), in dosages of 200 liters; with the idea of evaluating the effectiveness of implementation of these new concretes at elements designed with conventional concrete (CCs).