Neutrino jets from high-mass WR gauge bosons in TeV-scale left-right symmetric models

Science.gov (United States)

Mitra, Manimala; Ruiz, Richard; Scott, Darren J.; Spannowsky, Michael

2016-11-01

We reexamine the discovery potential at hadron colliders of high-mass right-handed (RH) gauge bosons WR—an inherent ingredient of left-right symmetric models (LRSM). We focus on the regime where the WR is very heavy compared to the heavy Majorana neutrino N , and we investigate an alternative signature for WR→N decays. The produced neutrinos are highly boosted in this mass regime. Subsequently, their decays via off-shell WR bosons to jets, i.e., N →ℓ±jj, are highly collimated, forming a single neutrino jet (jN). The final-state collider signature is then ℓ±jN, instead of the widely studied ℓ±ℓ±j j . Present search strategies are not sensitive to this hierarchical mass regime due to the breakdown of the collider signature definition. We take into account QCD corrections beyond next-to-leading order (NLO) that are important for high-mass Drell-Yan processes at the 13 TeV Large Hadron Collider (LHC). For the first time, we evaluate WR production at NLO with threshold resummation at next-to-next-to-leading logarithm (NNLL) matched to the threshold-improved parton distributions. With these improvements, we find that a WR of mass MWR=3 (4 )[5 ] TeV and mass ratio of (mN/MWR)discovered with a 5 - 6 σ statistical significance at 13 TeV after 10 (100 )[2000 ] fb-1 of data. Extending the analysis to the hypothetical 100 TeV Very Large Hadron Collider (VLHC), 5 σ can be obtained for WR masses up to MW R=15 (30 ) with approximately 100 fb-1 (10 ab-1 ). Conversely, with 0.9 (10 )[150 ] fb-1 of 13 TeV data, MWR<3 (4 )[5 ] TeV and (mN/MWR)<0.1 can be excluded at 95% C.L.; with 100 fb-1 (2.5 ab-1 ) of 100 TeV data, MW R<22 (33 ) TeV can be excluded.

Colliding Stellar Winds Structure and X-ray Emission

Science.gov (United States)

Pittard, J. M.; Dawson, B.

2018-04-01

We investigate the structure and X-ray emission from the colliding stellar winds in massive star binaries. We find that the opening angle of the contact discontinuity (CD) is overestimated by several formulae in the literature at very small values of the wind momentum ratio, η. We find also that the shocks in the primary (dominant) and secondary winds flare by ≈20° compared to the CD, and that the entire secondary wind is shocked when η ≲ 0.02. Analytical expressions for the opening angles of the shocks, and the fraction of each wind that is shocked, are provided. We find that the X-ray luminosity Lx∝η, and that the spectrum softens slightly as η decreases.

Time and Energy Efficient DVS Scheduling for Real-Time Pinwheel Tasks

OpenAIRE

Da-Ren, Chen; Young-Long, Chen; You-Shyang, Chen

2014-01-01

Dynamic voltage/frequency scaling (DVFS) is one of the most effective techniques for reducing energy use. In this paper, we focus on the pinwheel task model to develop a variable voltage processor with d discrete voltage/speed levels. Depending on the granularity of execution unit to which voltage scaling is applied, DVFS scheduling can be defined in two categories: (i) inter-task DVFS and (ii) intra-task DVFS. In the periodic pinwheel task model, we modified the definitions of both intra- an...

Variable millimetre radiation from the colliding-wind binary Cygnus OB2 #8A

Science.gov (United States)

Blomme, R.; Fenech, D. M.; Prinja, R. K.; Pittard, J. M.; Morford, J. C.

2017-12-01

Context. Massive binaries have stellar winds that collide. In the colliding-wind region, various physically interesting processes occur, leading to enhanced X-ray emission, non-thermal radio emission, as well as non-thermal X-rays and gamma-rays. Non-thermal radio emission (due to synchrotron radiation) has so far been observed at centimetre wavelengths. At millimetre wavelengths, the stellar winds and the colliding-wind region emit more thermal free-free radiation, and it is expected that any non-thermal contribution will be difficult or impossible to detect. Aims: We aim to determine if the material in the colliding-wind region contributes substantially to the observed millimetre fluxes of a colliding-wind binary. We also try to distinguish the synchrotron emission from the free-free emission. Methods: We monitored the massive binary Cyg OB2 #8A at 3 mm with the NOrthern Extended Millimeter Array (NOEMA) interferometer of the Institut de Radioastronomie Millimétrique (IRAM). The data were collected in 14 separate observing runs (in 2014 and 2016), and provide good coverage of the orbital period. Results: The observed millimetre fluxes range between 1.1 and 2.3 mJy, and show phase-locked variability, clearly indicating that a large part of the emission is due to the colliding-wind region. A simple synchrotron model gives fluxes with the correct order of magnitude, but with a maximum that is phase-shifted with respect to the observations. Qualitatively this phase shift can be explained by our neglect of orbital motion on the shape of the colliding-wind region. A model using only free-free emission results in only a slightly worse explanation of the observations. Additionally, on the map of our observations we also detect the O6.5 III star Cyg OB2 #8B, for which we determine a 3 mm flux of 0.21 ± 0.033 mJy. Conclusions: The question of whether synchrotron radiation or free-free emission dominates the millimetre fluxes of Cyg OB2 #8A remains open. More detailed

Applying dynamic priority scheduling scheme to static systems of pinwheel task model in power-aware scheduling.

Science.gov (United States)

Seol, Ye-In; Kim, Young-Kuk

2014-01-01

Power-aware scheduling reduces CPU energy consumption in hard real-time systems through dynamic voltage scaling (DVS). In this paper, we deal with pinwheel task model which is known as static and predictable task model and could be applied to various embedded or ubiquitous systems. In pinwheel task model, each task's priority is static and its execution sequence could be predetermined. There have been many static approaches to power-aware scheduling in pinwheel task model. But, in this paper, we will show that the dynamic priority scheduling results in power-aware scheduling could be applied to pinwheel task model. This method is more effective than adopting the previous static priority scheduling methods in saving energy consumption and, for the system being still static, it is more tractable and applicable to small sized embedded or ubiquitous computing. Also, we introduce a novel power-aware scheduling algorithm which exploits all slacks under preemptive earliest-deadline first scheduling which is optimal in uniprocessor system. The dynamic priority method presented in this paper could be applied directly to static systems of pinwheel task model. The simulation results show that the proposed algorithm with the algorithmic complexity of O(n) reduces the energy consumption by 10-80% over the existing algorithms.

Highly reliable wind-rolling triboelectric nanogenerator operating in a wide wind speed range

Science.gov (United States)

Yong, Hyungseok; Chung, Jihoon; Choi, Dukhyun; Jung, Daewoong; Cho, Minhaeng; Lee, Sangmin

2016-01-01

Triboelectric nanogenerators are aspiring energy harvesting methods that generate electricity from the triboelectric effect and electrostatic induction. This study demonstrates the harvesting of wind energy by a wind-rolling triboelectric nanogenerator (WR-TENG). The WR-TENG generates electricity from wind as a lightweight dielectric sphere rotates along the vortex whistle substrate. Increasing the kinetic energy of a dielectric converted from the wind energy is a key factor in fabricating an efficient WR-TENG. Computation fluid dynamics (CFD) analysis is introduced to estimate the precise movements of wind flow and to create a vortex flow by adjusting the parameters of the vortex whistle shape to optimize the design parameters to increase the kinetic energy conversion rate. WR-TENG can be utilized as both a self-powered wind velocity sensor and a wind energy harvester. A single unit of WR-TENG produces open-circuit voltage of 11.2 V and closed-circuit current of 1.86 μA. Additionally, findings reveal that the electrical power is enhanced through multiple electrode patterns in a single device and by increasing the number of dielectric spheres inside WR-TENG. The wind-rolling TENG is a novel approach for a sustainable wind-driven TENG that is sensitive and reliable to wind flows to harvest wasted wind energy in the near future. PMID:27653976

Measurement of WR-2721, WR-1065, and WR-33278 in plasma

International Nuclear Information System (INIS)

Fahey, R.C.; Newton, G.L.

1985-01-01

Alkaline phosphatase was used in developing two new assays for WR-2721; one involved simple spectrophotometric titration with Ellman's reagent and the other was based upon HPLC analysis of a monobromobimane derivative. Both methods have acceptable results when applied to whole plasma. Assays for WR-1065 and disulfide forms of the drug were also developed but were found to give unreliable results with whole plasma owing to apparent rapid reaction of these drug forms with plasma constituents. The methods were applied to the analysis of blood samples in rat 0-70 min after i.v. injection of WR-2721

Role of ionization fronts in the colliding wind model of planetary nebulae

International Nuclear Information System (INIS)

Giuliani, J.L. Jr.

1981-01-01

A similarity transformation is used to study the expansion of a planetary nebula which is driven by a fast stellar wind as well as an expanding H II region. The undisturbed gas is taken to be the remnant of a slow, red giant wind. The present analysis improves upon Kwok, Purton, and FitzGerald's colliding wind model for the formation of planetary nebulae since it includes the dynamical influence of ionization fronts, and calculates the variation of velocity and density within the flow

Pharmacokinetics of WR-1065 in mouse tissue following treatment with WR-2721

International Nuclear Information System (INIS)

Utley, J.F.; Seaver, N.; Newton, G.L.; Fahey, R.C.

1984-01-01

Levels of reduced glutathione (GSH) and N-(2-mercaptoethyl)-1,3-diaminopropane (WR-1065) were measured in tissues of Balb/c mouse bearing EMT 6 tumors at time intervals ranging from 5 min to 48 hr after i.v. injection of S-2-(3-aminopropylamino)ethyl phosphorothioate (WR-2721) at 500 mg per kg. In all tissues examined (liver, kidney, lung, heart, muscle, brain, tumor, spleen, and salivary gland), maximal WR-1065 levels occurred 5-15 min after injection, with levels in liver, kidney, lung, and salivary gland exceeding one μmole per gm. The post-maximum decline in WR-1065 varied markedly with tissue, lung exhibiting a 6-fold drop by 30 min and salivary gland falling only 15% after 3 hr. In a mouse treated with carbon-14 labeled WR-2721 it was found after 15 min that WR-1065 accounted for over half of the total drug in all tissues except tumor, where it accounted for a third of the total drug. There was no evidence that GSH levels were substantially altered by WR-2721 treatment. The results provide the first direct evidence supporting the widely held view that WR-2721 treatment results in intracellular WR-1065 and they demonstrate that high levels of WR-1065 occur very soon after i.v. injection

Observations and numerical studies of gamma-ray emission in colliding-wind binaries

International Nuclear Information System (INIS)

Reitberger, K.

2014-01-01

Massive stars in binary systems have long been regarded as potential sources of high-energy gamma rays. The emission is thought to arise in the region where the stellar winds collide, thereby producing accelerated particles which subsequently emit gamma rays.This scenario is supported by observations with the Fermi Large Area Telescope presented in this thesis. To address the underlying emission mechanisms in a quantitative way, numerical simulations that incorporate hydrodynamics, the acceleration of charged particles as well as the subsequent gamma-ray emission were found to be needed.This thesis presents the analysis of a high-energy gamma-ray source and its identification with the particle-accelerating colliding-wind binary system Eta Carinae. In order to go beyond the present understanding of such objects, this work provides detailed description of a new 3D-hydrodynamical model, which incorporates the line-driven acceleration of the winds, gravity, orbital motion and the radiative cooling of the shocked plasma, as well as the diffusive shock acceleration of charged particles in the wind collision region. In a subsequent step we simulate and study the resulting gamma-ray emission via relativistic bremsstrahlung, anisotropic inverse Compton radiation and neutral pion decay. (author) [de

Non-thermal Processes in Colliding-wind Massive Binaries: the Contribution of Simbol-X to a Multiwavelength Investigation

Science.gov (United States)

De Becker, Michaël; Blomme, Ronny; Micela, Giusi; Pittard, Julian M.; Rauw, Gregor; Romero, Gustavo E.; Sana, Hugues; Stevens, Ian R.

2009-05-01

Several colliding-wind massive binaries are known to be non-thermal emitters in the radio domain. This constitutes strong evidence for the fact that an efficient particle acceleration process is at work in these objects. The acceleration mechanism is most probably the Diffusive Shock Acceleration (DSA) process in the presence of strong hydrodynamic shocks due to the colliding-winds. In order to investigate the physics of this particle acceleration, we initiated a multiwavelength campaign covering a large part of the electromagnetic spectrum. In this context, the detailed study of the hard X-ray emission from these sources in the SIMBOL-X bandpass constitutes a crucial element in order to probe this still poorly known topic of astrophysics. It should be noted that colliding-wind massive binaries should be considered as very valuable targets for the investigation of particle acceleration in a similar way as supernova remnants, but in a different region of the parameter space.

Chemical protection against gastrointestinal radiation injury in mice by WR 2822, WR 2823, or WR 109342 after 4 MeV x ray or fission neutron irradiation

International Nuclear Information System (INIS)

Connor, A.M.; Sigdestad, C.P.

1982-01-01

Three compounds were tested for their radioprotective properties against the effects of 4 MeV X rays or fission neutron irradiation. The endpoints tested were lethality, intestinal crypt survival, and DNA synthesizing cellularity. Two of the compounds tested; S-2(4-aminobutylamino) ethylphosphorothioc acid (WR 2822) and the aminopentylamino derivative (WR 109342). All drugs were administered via intraperitoneal injections at their approximately maximum tolerated dose. WR 2822 was shown to have a slight protective effect against X rays and neutrons. The dose modification factor (DMF) for gastrointestinal death (LD/sub 50(6)/) was 1.23 for X rays and 1.51 for neutrons. The assay for intestinal crypt survival produced DMF's of 1.44 (X rays) and 1.4 (neutrons). WR 2823 also showed a protective action in these assays. The DMF for LD/sub 50(6)/ was 1.32 (X rays) and 1.42 (neutrons). WR 109342 was found to be extremely toxic and had no significant protective effects. All three drugs were more toxic and demonstrated less protection in most of these assays than the benchmark radioprotective agent WR 2721, although WR 2822 protected against lethal effects of fission neutrons almost as well as WR 2721. Both WR 2822 and WR 2823 produced greater protection in the crypt survival assays for fission neutron irradiation than WR 2721

Comparative study of the radioprotective effects of cysteamine, WR-2721, and WR-1065 in cultured human cells

International Nuclear Information System (INIS)

Purdie, J.W.

1979-01-01

The compounds, 2-mercaptoethylamine (cysteamine), S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721), and N-(2-mercaptoethyl)-1,3-diaminopropane (WR-1065) were tested for toxicity and radioprotective effect in cultured human cells using viability (reproductive death) as an indicator. WR-2721 and WR-1065 had no harmful effect at concentrations of 4 and 10 mM for periods up to 3 hr whereas cysteamine was toxic if left in contact with the cells for more than 30 min. The response of the cells to radiation was measured after a 30-min treatment with 4 mM of each protective agent. Survival curves were constructed and the following dose reduction factors (DRFs) were calculated: WR-2721, 1.3; cysteamine, 2.3; WR-1065, 2.9. Increasing the concentration of protective agent did not increase the DRF under these conditions except in the case of cysteamine. Extending the period of treatment with drug before irradiation increased the DRF for WR-2721 and WR-1065; values up to 1.8 and 3.4 were obtained with 10 mM WR-2721 and WR-1065, respectively. With these two compounds, the rate of development of protection with time is almost independent of concentration until the maximum is attained; it is probably controlled by the rate of transport across the cell membrane, in the case of WR-1065, and by the rate of hydrolysis of WR-2721

Opposite effects of WR-2721 and WR-1065 on radiation-induced hypothermia: possible correlation with oxygen uptake

International Nuclear Information System (INIS)

Kandasamy, S.B.; Kumar, K.S.; Hunt, W.A.; Weiss, J.F.

1988-01-01

Ionizing radiation induces hypothermia in guinea pigs. While systemic injection of the radioprotectant S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721) did not block hyperthermia induced by exposure to 10 Gy of gamma radiation, central administration did attenuate it. The dephosphorylated metabolite of WR-2721, N-(2-mercaptoethyl)-1,3-diaminopropane (WR-1065), accentuated radiation-induced hypothermia by both routes of administration. In brain homogenates, oxygen uptake was inhibited by WR-2721 but elevated by WR-1065. These results suggest that the antagonism of radiation-induced hypothermia found only after central administration of WR-2721 is due to its direct actions and not to its dephosphorylated metabolite and that this effect may be correlated with the inhibition by WR-2721 of oxygen uptake

Chemoprevention by WR-2721

Energy Technology Data Exchange (ETDEWEB)

Grdina, D.J. [Argonne National Lab., IL (United States)]|[Chicago Univ., IL (United States). Dept. of Radiation and Cellular Oncology; Carnes, B.A. [Argonne National Lab., IL (United States)

1993-05-01

WR-2721 [S-2-(3-aminopropylamino)ethylphosphorothioic acid] is an effective chemopreventive agent. C57BL {times} BALB/c F{sub 1} female mice, were exposed to a single whole-body dose of 206 cGy from a {sup 60}Co photon source. Those groups treated with VATR-2721 (400 mg/kg) were administered the agent i.p. 30 min prior to irradiation. Over 90% of deaths were determined to be due to tumor involvement. WR-2721 afforded significant protection against life shortening due to radiation-induced tumors of connective tissue and epithelial tissue origins. Subsequent survival time in WR-2721-treated and irradiated animals as compared to matched irradiated-only controls was extended up to 59 days. A single exposure of animals to VVR-2721 did not affect the cumulative survival curves for unirradiated mice. WR-2721 possesses chemopreventive properties which can be clinically exploited to reduce the risk to therapy-induced secondary cancers in patients who otherwise would have an excellent prognosis for cure and long-term survival.

Chemoprevention by WR-2721

Energy Technology Data Exchange (ETDEWEB)

Grdina, D.J. (Argonne National Lab., IL (United States) Chicago Univ., IL (United States). Dept. of Radiation and Cellular Oncology); Carnes, B.A. (Argonne National Lab., IL (United States))

1993-01-01

WR-2721 [S-2-(3-aminopropylamino)ethylphosphorothioic acid] is an effective chemopreventive agent. C57BL [times] BALB/c F[sub 1] female mice, were exposed to a single whole-body dose of 206 cGy from a [sup 60]Co photon source. Those groups treated with VATR-2721 (400 mg/kg) were administered the agent i.p. 30 min prior to irradiation. Over 90% of deaths were determined to be due to tumor involvement. WR-2721 afforded significant protection against life shortening due to radiation-induced tumors of connective tissue and epithelial tissue origins. Subsequent survival time in WR-2721-treated and irradiated animals as compared to matched irradiated-only controls was extended up to 59 days. A single exposure of animals to VVR-2721 did not affect the cumulative survival curves for unirradiated mice. WR-2721 possesses chemopreventive properties which can be clinically exploited to reduce the risk to therapy-induced secondary cancers in patients who otherwise would have an excellent prognosis for cure and long-term survival.

Adverse effects of the radioprotector WR2721

International Nuclear Information System (INIS)

Cairnie, A.B.

1983-01-01

S-2-(3-Aminopropylamino)ethylphosphorothioic acid (WR2721) has radioprotective properties, but it is also toxic - in man it causes nausea and vomiting. Since radiation also causes nausea and vomiting it is important to know whether WR2721 would increase or decrease the likelihood of nausea and vomiting after radiation. This question was investigated in rats using the phenomenon of aversion to the taste of saccharin, which is readily inducible and is understood to be controlled in rats by the same pathways that control nausea and vomiting in man. The taste aversion was induced by giving 0.2 Gy 60 Co γ radiation 30 min after drinking 0.1% saccharin, or WR2721 immediately after the saccharin, or giving both radiation and WR2721. There were appropriate controls. In sham-irradiated rats, WR2721 (40 or 200 mg/kg, but not 8 mg/kg) produced a significant taste aversion. When WR2721 (40 or 200 mg/kg) was given immediately after the saccharin to irradiated rats it increased the taste aversion significantly, but it did not have any effect at 8 mg/kg. It was concluded that at doses which were optimal for radioprotection (approx.200 mg/kg) or lower, WR2721 increased in rats the taste aversion induced by radiation. By inference if conditioned taste aversion is an appropriate paradigm, WR2721 would increase nausea and vomiting in man induced by radiation

Coalescence of 3-phenyl-propynenitrile on Cu(111) into interlocking pinwheel chains

Science.gov (United States)

Luo, Miaomiao; Lu, Wenhao; Kim, Daeho; Chu, Eric; Wyrick, Jon; Holzke, Connor; Salib, Daniel; Cohen, Kamelia D.; Cheng, Zhihai; Sun, Dezheng; Zhu, Yeming; Einstein, T. L.; Bartels, Ludwig

2011-10-01

3-phenyl-propynenitrile (PPN) adsorbs on Cu(111) in a hexagonal network of molecular trimers formed through intermolecular interaction of the cyano group of one molecule with the aromatic ring of its neighbor. Heptamers of trimers coalesce into interlocking pinwheel-shaped structures that, by percolating across islands of the original trimer coverage, create the appearance of gear chains. Density functional theory aids in identifying substrate stress associated with the chemisorption of PPN's acetylene group as the cause of this transition.

Creating an enabling environment for WR&R implementation.

Science.gov (United States)

Stathatou, P-M; Kampragou, E; Grigoropoulou, H; Assimacopoulos, D; Karavitis, C; Gironás, J

2017-09-01

Reclaimed water is receiving growing attention worldwide as an effective solution for alleviating the growing water scarcity in many areas. Despite the various benefits associated with reclaimed water, water recycling and reuse (WR&R) practices are not widely applied around the world. This is mostly due to complex and inadequate local legal and institutional frameworks and socio-economic structures, which pose barriers to wider WR&R implementation. An integrated approach is therefore needed while planning the implementation of WR&R schemes, considering all the potential barriers, and aiming to develop favourable conditions for enhancing reclaimed water use. This paper proposes a comprehensive methodology supporting the development of an enabling environment for WR&R implementation. The political, economic, social, technical, legal and institutional factors that may influence positively (drivers) or negatively (barriers) WR&R implementation in the regional water systems are identified, through the mapping of local stakeholder perceptions. The identified barriers are further analysed, following a Cross-Impact/System analysis, to recognize the most significant barriers inhibiting system transition, and to prioritize the enabling instruments and arrangements that are needed to boost WR&R implementation. The proposed methodology was applied in the Copiapó River Basin in Chile, which faces severe water scarcity. Through the analysis, it was observed that barriers outweigh drivers for the implementation of WR&R schemes in the Copiapó River Basin, while the key barriers which could be useful for policy formulation towards an enabling environment in the area concern the unclear legal framework regarding the ownership of treated wastewater, the lack of environmental policies focusing on pollution control, the limited integration of reclaimed water use in current land use and development policies, the limited public awareness on WR&R, and the limited availability of

Coupling hydrodynamics with comoving frame radiative transfer. I. A unified approach for OB and WR stars

Science.gov (United States)

Sander, A. A. C.; Hamann, W.-R.; Todt, H.; Hainich, R.; Shenar, T.

2017-07-01

Context. For more than two decades, stellar atmosphere codes have been used to derive the stellar and wind parameters of massive stars. Although they have become a powerful tool and sufficiently reproduce the observed spectral appearance, they can hardly be used for more than measuring parameters. One major obstacle is their inconsistency between the calculated radiation field and the wind stratification due to the usage of prescribed mass-loss rates and wind-velocity fields. Aims: We present the concepts for a new generation of hydrodynamically consistent non-local thermodynamical equilibrium (non-LTE) stellar atmosphere models that allow for detailed studies of radiation-driven stellar winds. As a first demonstration, this new kind of model is applied to a massive O star. Methods: Based on earlier works, the PoWR code has been extended with the option to consistently solve the hydrodynamic equation together with the statistical equations and the radiative transfer in order to obtain a hydrodynamically consistent atmosphere stratification. In these models, the whole velocity field is iteratively updated together with an adjustment of the mass-loss rate. Results: The concepts for obtaining hydrodynamically consistent models using a comoving-frame radiative transfer are outlined. To provide a useful benchmark, we present a demonstration model, which was motivated to describe the well-studied O4 supergiant ζPup. The obtained stellar and wind parameters are within the current range of literature values. Conclusions: For the first time, the PoWR code has been used to obtain a hydrodynamically consistent model for a massive O star. This has been achieved by a profound revision of earlier concepts used for Wolf-Rayet stars. The velocity field is shaped by various elements contributing to the radiative acceleration, especially in the outer wind. The results further indicate that for more dense winds deviations from a standard β-law occur.

Interaction of cultured mammalian cells with WR-2721 and its thiol, WR-1065: implications for mechanisms of radioprotection

International Nuclear Information System (INIS)

Purdie, J.W.; Inhaber, E.R.; Schneider, H.; Labelle, J.L.

1983-01-01

An isothermal microcalorimeter was used to measure changes in heat flow when radioprotective drugs were added to cultured mammalian cells. The heat produced when WR-2721 was added continued for at least 90 min. WR-2721 was dephosphorylated by the cells to thiol (WR-1065) which oxidizes to disulphide. In the microcalorimeter, thiols give an immediate burst of heat due to this oxidation. A biological oxygen monitor revealed that WR-1065 and cysteamine rapidly consumed all the oxygen in culture medium. (10mM WR-1065 deoxygenated medium in 2 min.). Rapid consumption of oxygen by radioprotective thiols indicates that they will not co-exist with oxygen for long in cells. This has two important implications with respect to mechanisms of radioprotection: (1) oxygen in tissues will be consumed rapidly and could results in local hypoxia; and, (2) at modest doses of protective agents the thiol will be consumed in oxic cells and hence very little will be available for reactions such as hydrogen donation. The results indicate that anoxia is probably the principle mechanism of protection by aminothiols in mammals and aerated cells. (author)

XMM-Newton Detection of Hard X-Ray Emission in the Nitrogen-Type Wolf-Rayet Star WR 110

Science.gov (United States)

Skinner, Stephen L.; Zhekov, Svetozar A.; Güdel, Manuel; Schmutz, Werner

2002-06-01

We have used the excellent sensitivity of XMM-Newton to obtain the first high-quality X-ray spectrum of a Wolf-Rayet (W-R) star that is not known to be a member of a binary system. Our target, the nitrogen-type star WR 110 (HD 165688), was also observed and detected with the Very Large Array at four different frequencies. The radio flux density increases with frequency according to a power law Sν~ν+0.64+/-0.10, in very good agreement with the behavior expected for free-free wind emission. The radio data give an ionized mass-loss rate M=4.9×10-5 Msolar yr-1 for an assumed spherical constant-velocity wind. The undispersed CCD X-ray spectra reveal strong emission lines from He-like ions of Mg, Si, and S. The emission measure distribution shows a dominant contribution from cool plasma with a characteristic temperature kTcool~0.5 keV (~6 MK). Little or no excess absorption of this cool component above the value expected from the visual extinction is present. We conclude that the bulk of the cool plasma detected by XMM-Newton lies at hundreds of stellar radii or more if the wind is approximately spherical and homogeneous, but it could lie closer to the star if the wind is clumped. If the cool plasma is due to instability-driven wind shocks, then typical shock velocities are vs~340-550 km s-1 and the average filling factor of X-ray-emitting gas in the wind is no larger than f~10-6. A surprising result is the unambiguous detection of a hard X-ray component that is clearly seen in the hard-band images and the spectra. This hard component accounts for about half of the observed flux and can be acceptably fitted by a hot, optically thin thermal plasma or a power-law model. If the emission is thermal, then a temperature kThot>=3 keV is derived. Such high temperatures are not predicted by current instability-driven wind shock models, and a different mechanism is thus required to explain the hard X-rays. We examine several possible mechanisms and show that the hard emission

A Comparison of Wind Speed Data from Mechanical and Ultrasonic Anemometers

Science.gov (United States)

Short, D.; Wells, L.; Merceret, F.; Roeder, W. P.

2006-01-01

This study compared the performance of mechanical and ultrasonic anemometers at the Eastern Range (ER; Kennedy Space Center and Cape Canaveral Air Force Station on Florida's Atlantic coast) and the Western Range (WR; Vandenberg Air Force Base on California's Pacific coast). Launch Weather Officers, forecasters, and Range Safety analysts need to understand the performance of wind sensors at the ER and WR for weather warnings, watches, advisories, special ground processing operations, launch pad exposure forecasts, user Launch Commit Criteria (LCC) forecasts and evaluations, and toxic dispersion support. The current ER and WR weather tower wind instruments are being changed from the current propeller-and-vane (ER) and cup-and-vane (WR) sensors to ultrasonic sensors through the Range Standardization and Automation (RSA) program. The differences between mechanical and ultrasonic techniques have been found to cause differences in the statistics of peak wind speed in previous studies. The 45th Weather Squadron (45 WS) and the 30th Weather Squadron (30 WS) requested the Applied Meteorology Unit (AMU) to compare data between RSA and current sensors to determine if there are significant differences. Approximately 3 weeks of Legacy and RSA wind data from each range were used in the study, archived during May and June 2005. The ER data spanned the full diurnal cycle, while the WR data was confined to 1000-1600 local time. The sample of 1-minute data from numerous levels on 5 different towers on each range totaled more than 500,000 minutes of data (482,979 minutes of data after quality control). The 10 towers were instrumented at several levels, ranging from 12 ft to 492 ft above ground level. The RSA sensors were collocated at the same vertical levels as the present sensors and typically within 15 ft horizontally of each another. Data from a total of 53 RSA ultrasonic sensors, collocated with present sensors were compared. The 1-minute average wind speed/direction and the 1

3D printing meets computational astrophysics: deciphering the structure of η Carinae's inner colliding winds

Science.gov (United States)

Madura, T. I.; Clementel, N.; Gull, T. R.; Kruip, C. J. H.; Paardekooper, J.-P.

2015-06-01

We present the first 3D prints of output from a supercomputer simulation of a complex astrophysical system, the colliding stellar winds in the massive (≳120 M⊙), highly eccentric (e ˜ 0.9) binary star system η Carinae. We demonstrate the methodology used to incorporate 3D interactive figures into a PDF (Portable Document Format) journal publication and the benefits of using 3D visualization and 3D printing as tools to analyse data from multidimensional numerical simulations. Using a consumer-grade 3D printer (MakerBot Replicator 2X), we successfully printed 3D smoothed particle hydrodynamics simulations of η Carinae's inner (r ˜ 110 au) wind-wind collision interface at multiple orbital phases. The 3D prints and visualizations reveal important, previously unknown `finger-like' structures at orbital phases shortly after periastron (φ ˜ 1.045) that protrude radially outwards from the spiral wind-wind collision region. We speculate that these fingers are related to instabilities (e.g. thin-shell, Rayleigh-Taylor) that arise at the interface between the radiatively cooled layer of dense post-shock primary-star wind and the fast (3000 km s-1), adiabatic post-shock companion-star wind. The success of our work and easy identification of previously unrecognized physical features highlight the important role 3D printing and interactive graphics can play in the visualization and understanding of complex 3D time-dependent numerical simulations of astrophysical phenomena.

GeV gamma-rays and TeV neutrinos from very massive compact binary systems: The case of WR 20a

OpenAIRE

Bednarek, W.

2005-01-01

Massive Wolf-Rayet stars in a compact binary systems are characterised by very strong winds which collide creating a shock wave. If the wind nuclei accelerated at the shock can reach large enough energies, they suffer disintegration in collisions with soft thermal radiation from the massive stars injecting relativistic protons and neutrons. Protons collide with the matter of the wind and a fraction of neutrons colide with the massive stars producing gamma-rays and neutrinos. We calculate the ...

The pinwheel pupil discovery: exoplanet science & improved processing with segmented telescopes

Science.gov (United States)

Breckinridge, James Bernard

2018-01-01

In this paper, we show that by using a “pinwheel” architecture for the segmented primary mirror and curved supports for the secondary mirror, we can achieve a near uniform diffraction background in ground and space large telescope systems needed for high SNR exoplanet science. Also, the point spread function will be nearly rotationally symmetric, enabling improved digital image reconstruction. Large (>4-m) aperture space telescopes are needed to characterize terrestrial exoplanets by direct imaging coronagraphy. Launch vehicle volume constrains these apertures are segmented and deployed in space to form a large mirror aperture that is masked by the gaps between the hexagonal segments and the shadows of the secondary support system. These gaps and shadows over the pupil result in an image plane point spread function that has bright spikes, which may mask or obscure exoplanets.These telescope artifact mask faint exoplanets, making it necessary for the spacecraft to make a roll about the boresight and integrate again to make sure no planets are missed. This increases integration time, and requires expensive space-craft resources to do bore-sight roll.Currently the LUVOIR and HabEx studies have several significant efforts to develop special purpose A/O technology and to place complex absorbing apodizers over their Hex pupils to shape the unwanted diffracted light. These strong apodizers absorb light, decreasing system transmittance and reducing SNR. Implementing curved pupil obscurations will eliminate the need for the highly absorbing apodizers and thus result in higher SNR.Quantitative analysis of diffraction patterns that use the pinwheel architecture are compared to straight hex-segment edges with a straight-line secondary shadow mask to show a gain of over a factor of 100 by reducing the background. For the first-time astronomers are able to control and minimize image plane diffraction background “noise”. This technology will enable 10-m segmented

THE XMM-NEWTON/EPIC X-RAY LIGHT CURVE ANALYSIS OF WR 6

International Nuclear Information System (INIS)

Ignace, R.; Gayley, K. G.; Hamann, W.-R.; Oskinova, L. M.; Huenemoerder, D. P.; Pollock, A. M. T.; McFall, M.

2013-01-01

We obtained four pointings of over 100 ks each of the well-studied Wolf-Rayet star WR 6 with the XMM-Newton satellite. With a first paper emphasizing the results of spectral analysis, this follow-up highlights the X-ray variability clearly detected in all four pointings. However, phased light curves fail to confirm obvious cyclic behavior on the well-established 3.766 day period widely found at longer wavelengths. The data are of such quality that we were able to conduct a search for event clustering in the arrival times of X-ray photons. However, we fail to detect any such clustering. One possibility is that X-rays are generated in a stationary shock structure. In this context we favor a corotating interaction region (CIR) and present a phenomenological model for X-rays from a CIR structure. We show that a CIR has the potential to account simultaneously for the X-ray variability and constraints provided by the spectral analysis. Ultimately, the viability of the CIR model will require both intermittent long-term X-ray monitoring of WR 6 and better physical models of CIR X-ray production at large radii in stellar winds

THE XMM-NEWTON/EPIC X-RAY LIGHT CURVE ANALYSIS OF WR 6

Energy Technology Data Exchange (ETDEWEB)

Ignace, R. [Department of Physics and Astronomy, East Tennessee State University, Johnson City, TN 37663 (United States); Gayley, K. G. [Department of Physics and Astronomy, University of Iowa, Iowa City, IA 52245 (United States); Hamann, W.-R.; Oskinova, L. M. [Institute for Physics and Astronomy, University Potsdam, D-14476 Potsdam (Germany); Huenemoerder, D. P. [Massachusetts Institute of Technology, Kavli Institute for Astrophysics and Space Research, 70 Vassar Street, Cambridge, MA 02139 (United States); Pollock, A. M. T. [European Space Agency XMM-Newton Science Operations Centre, European Space Astronomy Centre, Apartado 78, Villanueva de la Cañada, E-28691 Madrid (Spain); McFall, M., E-mail: ignace@etsu.edu [Department of Physics, 191 W. Woodruff Avenue, Ohio State University, Columbus, OH 43210 (United States)

2013-09-20

We obtained four pointings of over 100 ks each of the well-studied Wolf-Rayet star WR 6 with the XMM-Newton satellite. With a first paper emphasizing the results of spectral analysis, this follow-up highlights the X-ray variability clearly detected in all four pointings. However, phased light curves fail to confirm obvious cyclic behavior on the well-established 3.766 day period widely found at longer wavelengths. The data are of such quality that we were able to conduct a search for event clustering in the arrival times of X-ray photons. However, we fail to detect any such clustering. One possibility is that X-rays are generated in a stationary shock structure. In this context we favor a corotating interaction region (CIR) and present a phenomenological model for X-rays from a CIR structure. We show that a CIR has the potential to account simultaneously for the X-ray variability and constraints provided by the spectral analysis. Ultimately, the viability of the CIR model will require both intermittent long-term X-ray monitoring of WR 6 and better physical models of CIR X-ray production at large radii in stellar winds.

HIGH-RESOLUTION X-RAY SPECTROSCOPY REVEALS THE SPECIAL NATURE OF WOLF-RAYET STAR WINDS

Energy Technology Data Exchange (ETDEWEB)

Oskinova, L. M.; Hamann, W.-R. [Institute for Physics and Astronomy, University Potsdam, 14476 Potsdam (Germany); Gayley, K. G. [Department of Physics and Astronomy, University of Iowa, Iowa City, IA 52245 (United States); Huenemoerder, D. P. [Massachusetts Institute of Technology, Kavli Institute for Astrophysics and Space Research, 70 Vassar St., Cambridge, MA 02139 (United States); Ignace, R. [Department of Physics and Astronomy, East Tennessee State University, Johnson City, TN 37663 (United States); Pollock, A. M. T., E-mail: lida@astro.physik.uni-potsdam.de [European Space Agency XMM-Newton Science Operations Centre, European Space Astronomy Centre, Apartado 78, Villanueva de la Canada, 28691 Madrid (Spain)

2012-03-10

We present the first high-resolution X-ray spectrum of a putatively single Wolf-Rayet (WR) star. 400 ks observations of WR 6 by the XMM-Newton telescope resulted in a superb quality high-resolution X-ray spectrum. Spectral analysis reveals that the X-rays originate far out in the stellar wind, more than 30 stellar radii from the photosphere, and thus outside the wind acceleration zone where the line-driving instability (LDI) could create shocks. The X-ray emitting plasma reaches temperatures up to 50 MK and is embedded within the unshocked, 'cool' stellar wind as revealed by characteristic spectral signatures. We detect a fluorescent Fe line at Almost-Equal-To 6.4 keV. The presence of fluorescence is consistent with a two-component medium, where the cool wind is permeated with the hot X-ray emitting plasma. The wind must have a very porous structure to allow the observed amount of X-rays to escape. We find that neither the LDI nor any alternative binary scenario can explain the data. We suggest a scenario where X-rays are produced when the fast wind rams into slow 'sticky clumps' that resist acceleration. Our new data show that the X-rays in single WR star are generated by some special mechanism different from the one operating in the O-star winds.

Simulating three-dimensional nonthermal high-energy photon emission in colliding-wind binaries

Energy Technology Data Exchange (ETDEWEB)

Reitberger, K.; Kissmann, R.; Reimer, A.; Reimer, O., E-mail: klaus.reitberger@uibk.ac.at [Institut für Astro- und Teilchenphysik and Institut für Theoretische Physik, Leopold-Franzens-Universität Innsbruck, A-6020 Innsbruck (Austria)

2014-07-01

Massive stars in binary systems have long been regarded as potential sources of high-energy γ rays. The emission is principally thought to arise in the region where the stellar winds collide and accelerate relativistic particles which subsequently emit γ rays. On the basis of a three-dimensional distribution function of high-energy particles in the wind collision region—as obtained by a numerical hydrodynamics and particle transport model—we present the computation of the three-dimensional nonthermal photon emission for a given line of sight. Anisotropic inverse Compton emission is modeled using the target radiation field of both stars. Photons from relativistic bremsstrahlung and neutral pion decay are computed on the basis of local wind plasma densities. We also consider photon-photon opacity effects due to the dense radiation fields of the stars. Results are shown for different stellar separations of a given binary system comprising of a B star and a Wolf-Rayet star. The influence of orbital orientation with respect to the line of sight is also studied by using different orbital viewing angles. For the chosen electron-proton injection ratio of 10{sup –2}, we present the ensuing photon emission in terms of two-dimensional projections maps, spectral energy distributions, and integrated photon flux values in various energy bands. Here, we find a transition from hadron-dominated to lepton-dominated high-energy emission with increasing stellar separations. In addition, we confirm findings from previous analytic modeling that the spectral energy distribution varies significantly with orbital orientation.

ON THE LAUNCHING AND STRUCTURE OF RADIATIVELY DRIVEN WINDS IN WOLF–RAYET STARS

Energy Technology Data Exchange (ETDEWEB)

Ro, Stephen; Matzner, Christopher D., E-mail: ro@astro.utoronto.ca [Department of Astronomy and Astrophysics, University of Toronto, 50 St. George Street, Toronto, ON M5S 3H4 (Canada)

2016-04-20

Hydrostatic models of Wolf–Rayet (WR) stars typically contain low-density outer envelopes that inflate the stellar radii by a factor of several and are capped by a denser shell of gas. Inflated envelopes and density inversions are hallmarks of envelopes that become super-Eddington as they cross the iron-group opacity peak, but these features disappear when mass loss is sufficiently rapid. We re-examine the structures of steady, spherically symmetric wind solutions that cross a sonic point at high optical depth, identifying the physical mechanism through which the outflow affects the stellar structure, and provide an improved analytical estimate for the critical mass-loss rate above which extended structures are erased. Weak-flow solutions below this limit resemble hydrostatic stars even in supersonic zones; however, we infer that these fail to successfully launch optically thick winds. WR envelopes will therefore likely correspond to the strong, compact solutions. We also find that wind solutions with negligible gas pressure are stably stratified at and below the sonic point. This implies that convection is not the source of variability in WR stars, as has been suggested; however, acoustic instabilities provide an alternative explanation. Our solutions are limited to high optical depths by our neglect of Doppler enhancements to the opacity, and do not account for acoustic instabilities at high Eddington factors; yet, they do provide useful insights into WR stellar structures.

Effect of radioprotectant WR 2721 on cyclic nucleotides, prostaglandins, and lysosomes

International Nuclear Information System (INIS)

Trocha, P.J.; Catravas, G.N.

1983-01-01

Within 1 hr after ip injection of the radioprotectant WR 2721 into rats, splenic cGMP levels dropped and remained suppressed for 6 hr before returning to normal. However, if rats were exposed to ionizing radiation 30-40 min after WR 2721 treatment, they had higher cGMP levels at 3 hr postirradiation than the nonirradiUted, drug-treated controls, but the cGMP content was still found to be lower than that of the irradiated nondrug-treated controls. Radiation exposure of animals pretreated with WR 2721 also resulted in higher liver and spleen levels of cAMP and additional elevations in spleen prostaglandin content, compared with irradiated controls at 3-6 hr after radiation treatment. The secondary fluctuations of lysosomal enzyme activities, prostaglandin content, and cyclic nucleotide levels were also altered in irradiated rats pretreated with WR 2721 when compared with irradiated controls. Liver and spleen lysosomal β-glucuronidase activities, spleen cAMP and cGMP levels, and spleen prostaglandin concentrations were closer to physiological levels at 3 days postirradiation in rats given WR 2721 before the radiation treatment

WR stars with ring nebulae

International Nuclear Information System (INIS)

Tutukov, A.

1982-01-01

It is shown that most of usually apparently single nitrogen WR stars with ring emission nebulae around them (WN + Neb) are a probable product of the evolution of a massive close binary with initial masses of components exceeding approximately 20 solar masses. (Auth.)

Prolonged radioprotective activity of WR-2721 linked to dextran

International Nuclear Information System (INIS)

Moenig, H.; Konermann, G.; Oehlert, W.

1990-01-01

The radioprotective agent WR-2721 was linked to dextran and poly(glutamic acid) respectively, to obtain a prolonged radioprotective ability. Male mice were administered these water soluble polymer conjugates one to 72 hours prior to a whole body irradiation with X-rays. A prolongation of radioprotective efficiency was achieved with two dextran-(WR-2721)-conjugates. For a period of 24 hours between administration, and irradiation dose reduction factors of 1.14±0.04 and 1.10±0.03 respectively were found. After 72 hours, no protective effect was observed. Histopathological investigations of the liver for formation of tumors 200 to 600 days after irradiation seems to indicate that a protective effect is not produced by the dextran-(WR-2721)-conjugats. (orig.) [de

Eclipses and dust formation by WC9 type Wolf-Rayet stars

Science.gov (United States)

Williams, P. M.

2014-12-01

Visual photometry of 16 WC8-9 dust-making Wolf-Rayet (WR) stars during 2001-2009 was extracted from the All-Sky Automated Survey All Star Catalogue (ASAS-3) to search for eclipses attributable to extinction by dust formed in clumps in our line of sight. Data for a comparable number of dust-free WC6-9 stars were also examined to help characterize the data set. Frequent eclipses were observed from WR 104, and several from WR 106, extending the 1994-2001 studies by Kato et al., but not supporting their phasing the variations in WR 104 with its `pinwheel' rotation period. Only four other stars showed eclipses, WR 50 (one of the dust-free stars), WR 69, WR 95 and WR 117, and there may have been an eclipse by WR 121, which had shown two eclipses in the past. No dust eclipses were shown by the `historic' eclipsers WR 103 and WR 113. The atmospheric eclipses of the latter were observed but the suggestion by David-Uraz et al. that dust may be partly responsible for these is not supported. Despite its frequent eclipses, there is no evidence in the infrared images of WR 104 for dust made in its eclipses, demonstrating that any dust formed in this process is not a significant contributor to its circumstellar dust cloud and suggesting that the same applies to the other stars showing fewer eclipses.

HPLC assay for 2-(3-aminopropylamino)ethanethiol (WR-1065) in plasma

International Nuclear Information System (INIS)

McGovern, E.P.; Swynnerton, N.F.; Steele, P.D.; Mangold, D.J.

1984-01-01

A high pressure liquid chromatography (HPLC) plasma assay for WR-1065 is described which is both precise and accurate throughout the concentration range from 1 to 500 μg/mL of plasma. The analyte is separated by HPLC and detected with a thiol specific electrochemical transducer cell. The detector response is linear over the ranges 1 to 10 μg/mL, 10 to 100 μg/mL, and 100 to 500 μg/mL. The absolute retention times for WR-1065 and WT-1729 are 9 and 12 minutes, respectively. The assay uses 100 μL of plasma and requires a total chromatography cycle time of 40 minutes. The method has been found suitable for the determination of WR-1065 in plasma from a beagle dog after i.v. administration of S-2-(3-aminopropylamino)ethyl phosphorothioate (WR-2721)

Local changes after intramuscular administration of gammaphos (WR-2721) in rats

International Nuclear Information System (INIS)

Resl, M.; Kuna, P.

1985-01-01

Local changes were investigated after i.m. injection of WR-2721, dissolved in saline or in aqua pro injectionem (ApI), and of ApI or saline alone. First muscle changes were found in the all the experimental groups after 6 h. Their development was most intensive after i.m. injection of ApI alone (granular degeneration up to complete necrosis of muscle fibers). The local changes after i.m. injection of WR-2721 in saline did not reach the intensity of changes of WR-2721 in ApI. The first reparative or regenerative changes were observed 72 hours after application. In the late phase (14th to 21st day) the normal tissue state was reached. The i.m. injection of WR-2721 in saline may be one of the possible routes of administration of this radioprotective substance. (author)

Phase I clinical studies with WR-2721

International Nuclear Information System (INIS)

Kligerman, M.M.; Shaw, M.T.; Slavik, M.; Yuhas, J.M.

1980-01-01

Toxicity studies of S-2-(3 aminopropylamino)-ethylphosphorothioic acid (WR-2721) access patients in remission following radiation therapy. The dose has been escalated from 25 to 250 mg/m2 without significant symptoms. Inconsistent variation in the systolic blood pressure in some patients has been observed over an 8-10-point range without producing any symptoms. Combining WR-2721 with conventional radiotherapy is contemplated by intravenous injection the drug 20 to 30 minutes before irradiation. This will start as weekly injections, and the number of weekly injections will be increased progessively. Animal studies suggest that the level already safely reached could give significant protection to the normal tissues without protecting tumor

Interspecies comparison of the tissue distribution of WR-2721, a radioprotective drug

International Nuclear Information System (INIS)

Washburn, L.C.; Rafter, J.J.; Hayes, R.L.; Yuhas, J.M.

1975-01-01

Pre-irradiation intravenous administration of the radioprotective drug S-2-[3-aminopropylamino]ethylphosphorothioic acid (WR-2721) has potential value in radiotherapy because it doubles the radiation resistance of normal mouse tissues while affording only minimal protection to tumors. Deficient deposition of WR- 2721 in tumor tissue has recently been demonstrated and this is thought to be a major reason for the preferential protection of normal tissues by the drug. Data originally obtained in studies using the mouse and rat indicated that the tissue distribution of WR-2721 was possibly more closely related to dose per unit surface area than to dose per unit weight. To test this hypothesis an interspecies comparison of the tissue distribution of 35 S-labeled WR-2721 was carried out in normal mice, rats, rabbits, and dogs at 15 and 30 minutes after intravenous administration. Results suggest that the surface area and body weight exert equal effects on the tissue concentration of WR-2721. The results further suggest that lower absolute doses of WR-2721 in the human, possibly as low as 20 mg/kg, may provide a radioprotective effect equivalent to that produced from 100 mg/kg in the mouse, i.e., a 50 to 80 percent increase in radiation resistance (CH)

Drifting on Alien Winds Exploring the Skies and Weather of Other Worlds

CERN Document Server

Carroll, Michael

2011-01-01

Drifting on Alien Winds explores the bizarre weather of alien worlds, from the blistering hurricane-force winds of Venus to the gentle methane rain showers of Saturn's giant moon Titan. Blinding bolts of lightning sizzle through Jupiter's skies, ammonia blizzards swirl through Saturnian clouds, and Earth-sized cyclones pinwheel across Uranus and Neptune. Late-breaking scientific discoveries from spacecraft, observatories, and laboratories reveal the mysteries of weather across the Solar System. Our knowledge of weather on other worlds has not come easily. Drifting on Alien Winds introduces the inventors, engineers, and scientists who struggled to launch the first probes that would help us to understand the atmospheres of other worlds. The untold stories of early engineering feats and failures, from small Soviet Venus balloons to advanced studies of blimps and airplanes for Mars and Titan, are showcased here, along with what we’ve learned and are still trying to learn about alien skies. Some of today’s mos...

Acute cardiovascular and autonomic effects of WR-2721: a radioprotective compound

International Nuclear Information System (INIS)

Caldwell, R.W.; Heiffer, M.H.

1975-01-01

WR-2721 is a chemical which has shown much promise as a protective agent in animals exposed to ionizing radiation. Our experiments on anesthetized dogs and cats indicate that WR-2721 has little acute cardiovascular action in these animals when given intravenously in doses of 50 to 200 mg/kg. A total cumulative dose of 600 mg/kg within 2 hr was not lethal and, indeed, was well tolerated. Arterial blood pressure was not markedly lowered in dogs and cats given these doses. In dogs, a slight vasodilation was noted in the femoral vascular bed after intra-arterial injection. Mydriasis and watery salivation were observed in all animals. In the dog, WR-2721 (100 mg/kg) was observed to produce blockade of the bilateral carotid artery-occlusion pressor response, the pressor response to the ganglionic stimulant DMPP, and the bradycardia to vagus nerve stimulation. In the cat, WR-2721 (100 mg/kg) also blocked the contraction of the cat nictitating membrane due to stimulation of the preganglionic fibers of the superior cervical ganglion, but not the contraction seen with postganglionic fiber stimulation. Our experiments indicate that WR-2721 is a ganglionic blocking agent. It does not share this property with closely related structural congeners. (U.S.)

Protection against radiation-induced mutations at the hprt locus by spermine and N,N double-prime-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278). WR-33278 and spermine protect against mutation induction

International Nuclear Information System (INIS)

Grdina, D.J.; Shigematsu, N.; Schwartz, J.L.

1994-01-01

The polyamine spermine and the disulfide N,N double-prime-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278) are structurally similar agents capable of binding to DNA. WR-33278 is the disulfide moiety of the clinically studied radioprotective agent S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721). Because of their reported structural and functional similarities, it was of interest to characterize and compare their radioprotective properties using the endpoints of cell survival and mutation induction at the hypoxanthine-guanine phosphoribosyl transferase (hprt) locus in Chinese hamster AA8 cells. In order to facilitate both the uptake of WR-33278 into cells and the direct comparison between the protective properties of WR-33278 and spermine, these agents (at concentrations of 0.01 mM and 0.001 mM) were electroporated into cells. The exposure of cells to both electroporation and irradiation gave rise to enhanced cell killing and mutation induction, with the sequence of irradiation followed 3 h later by electroporation being the more toxic protocol. Enhanced cell survival was observed following electroporation of 0.01 mM of spermine and WR-33278 30 min prior to irradiation; protection factors (PF) of 1.3 and 1.8, respectively. Neither agent was protective at a concentration of 0.001 mM. Protection against radiation-induced hprt mutations was observed for both spermine and WR-33278 under all experimental conditions tested. These data suggest that the properties of radioprotection and chemoprevention exhibited by the phosphorothioate (WR-2721) and associated aminothiol (WR-1065) and disulfide (WR-33278) metabolites may be mediated via endogenous spermine-like polyamine processes. Such a mechanism would have important implications with respect to the design and development of new generation drugs for use in radioprotection and chemoprevention

Chirality and Pinwheels

Science.gov (United States)

Rodriguez-Fernandez, Emilio

2013-01-01

By using cardboard models that resemble propellers, the students of inorganic courses can easily visualizing the distinct rotation of optical isomers. These propellers rotate clockwise or counterclockwise when they are dropped from a certain height or in the presence of wind. (Contains 1 figure.)

WR-1065 and radioprotection of vascular endothelial cells. I. Cell proliferation, DNA synthesis and damage

International Nuclear Information System (INIS)

Rubin, D.B.; Drab, E.A.; Kang, H.J.; Baumann, F.E.; Blazek, E.R.

1996-01-01

Normal tissue toxicity limits radiation therapy and could depend on the extent of damage to the vascular endothelium. Aminothiols such as WR-1065 [N-(2-mercaptoethyl)-1,3-diaminopropane] provide radioprotection for normal tissues, but little is known about how the aminothiols specifically affect the endothelium. Bovine aortic endothelial cells in culture were exposed to WR-1065 for 2 h before irradiation ( 137 Cs γ rays, 1 Gy/min). Alone, WR-1065 demonstrated an antiproliferative effect that was related to dose (0.5-4 mM) and was evident by lowered counts of adherent cells 48 h after exposure. WR-1065 was clearly radioprotective when assessed by colony formation and incorporation of [ 3 H]thymidine. However, when the number of adherent cells was evaluated, radioprotection appeared to be slight and evident only in logarithmically growing cells. WR-1065 at 2 mM suppressed single-strand DNA breaks after 3 Gy by 22% and double-strand breaks after 9 Gy by 47%. Also in the irradiated cells, WR-1065 more than doubled the rate of progression of cells from G 1 to S phase. WR-1065 pretreatment elevated cellular glutathione (GSH) content more than twofold. Although pretreatment with buthionine sulfoximine inhibited the elevation of GSH, the radioprotective impact of WR-1065 on total DNA strand breaks and colony formation was unaffected. These results suggest that WR-1065 may enable tissue recovery from irradiation by promoting the replication of endothelial cells, possibly by mechanisms independent of GSH. 46 refs., 6 figs., 2 tabs

The various scenarios leading to WR stars: Their relative importance and the role of mixing

International Nuclear Information System (INIS)

Maeder, A.

1982-01-01

Over the last 40 years WR stars have been associated with almost all possible evolutionary stages. The author lists 7 scenarios which may be considered as most relevant in view of recent surface abundance determinations. He then considers the importance of mass loss in WR formation and discusses properties of binary WR which suggest that formation is dependent on metallicity and thus galactic location. The role of internal mixing in WR formation is also considered. Mass loss on the MS is shown only to be able to explain a minute fraction of the observed WR stars, whereas internal mixing by shear instability has, for all stellar masses, a larger effect on MS evolution than mass loss. (Auth./C.F.)

Reduced protection of stem spermatogonia by WR-2721 at low doses of irradiation

International Nuclear Information System (INIS)

Meistrich, M.; Finch, M.; Hunter, N.; Milas, L.

1984-01-01

The radioprotection of normal cells with WR-2721 at low doses of radiation (about 2 Gy per fraction) was investigated using testicular stem cells. Survival of stem spermatogonia to single doses of irradiation, measured using sperm head counts at 56 days postirradiation, indicated no protection factor (PF = 1.00) at 2 GY by 400 mg/kg WR-2721, but a significant PF = 1.44 at 12 Gy. Stem cell survival was also measured after 5 fractions. When daily fractionation was used with 300 mg/kg WR-2721, given prior to each irradiation, little or no protection was observed at 2 Gy using the sperm head assay (PF = 0.98) or at 2.4 Gy using counts of repopulating tubules at 35 days postirradiation (PF = 1.12). In contrast, there was more significant protection (PF's = 1.22 and 1.27) for these two assays when 300 mg/kg WR-2721 was used with single high doses of radiation. When 4-hour fractionation was used with 300 mg/kg WR-2721, given prior to the first dose and 150 mg/kg prior to subsequent doses, minimal protection was observed at 2 Gy/fraction using the sperm head assay (PF = 0.98) and the repopulating tubule assay (PF = 1.09). Thus, protection of these cells in the clinical dose range is much lower than that observed at doses above 10 Gy. These results may be explained by a decrease in the intrinsic ability of WR-2721 to protect at lower radiation doses plus a cytotoxic effect of WR-2721

A SYSTEMATIC SEARCH FOR COROTATING INTERACTION REGIONS IN APPARENTLY SINGLE GALACTIC WOLF-RAYET STARS. II. A GLOBAL VIEW OF THE WIND VARIABILITY

International Nuclear Information System (INIS)

Chene, A.-N.; St-Louis, N.

2011-01-01

This study is the second part of a survey searching for large-scale spectroscopic variability in apparently single Wolf-Rayet (WR) stars. In a previous paper (Paper I), we described and characterized the spectroscopic variability level of 25 WR stars observable from the northern hemisphere and found 3 new candidates presenting large-scale wind variability, potentially originating from large-scale structures named corotating interaction regions (CIRs). In this second paper, we discuss an additional 39 stars observable from the southern hemisphere. For each star in our sample, we obtained 4-5 high-resolution spectra with a signal-to-noise ratio of ∼100 and determined its variability level using the approach described in Paper I. In total, 10 new stars are found to show large-scale spectral variability of which 7 present CIR-type changes (WR 8, WR 44, WR55, WR 58, WR 61, WR 63, WR 100). Of the remaining stars, 20 were found to show small-amplitude changes and 9 were found to show no spectral variability as far as can be concluded from the data on hand. Also, we discuss the spectroscopic variability level of all single galactic WR stars that are brighter than v ∼ 12.5, and some WR stars with 12.5 < v ≤ 13.5, i.e., all the stars presented in our two papers and four more stars for which spectra have already been published in the literature. We find that 23/68 stars (33.8%) present large-scale variability, but only 12/54 stars (∼22.1%) are potentially of CIR type. Also, we find that 31/68 stars (45.6%) only show small-scale variability, most likely due to clumping in the wind. Finally, no spectral variability is detected based on the data on hand for 14/68 (20.6%) stars. Interestingly, the variability with the highest amplitude also has the widest mean velocity dispersion.

Regiones H II alrededor de estrellas WR

Science.gov (United States)

Giménez Benitez, S.; Niemela, V.

En base a observaciones espectroscópicas en el rango óptico, obtenidas en el CASLEO, se estudian las condiciones físicas de tres regiones H II alrededor de estrellas WR: N76 en el entorno de Ab7, en la Nube Menor de Magallanes, N79 alrededor de Br 2, en la Nube Mayor de Magallanes y G2.4+1.4 alrededor de WR 102, en nuestra Galaxia. Estas regiones presentan una alta ionización. Se observa la línea nebular de HeII en 4686 Å . Utilizando líneas nebulares de diagnóstico, se derivan los valores de la densidad y la temperatura electrónica, así como también las abundancias de algunos de los elementos químicos nebulares.

SS433: the second Wolf-Rayet X-ray binary ?

OpenAIRE

Fuchs, Yael; Koch-Miramond, Lydie; Abraham, Peter

2002-01-01

We present mid-infrared spectrophotometric observations of SS433 with ISOPHOT. The HeI+HeII lines in both spectra of SS433 and of the Wolf-Rayet star WR147, a wind-colliding WN8+BO5 binary system, closely match. The 2.5-12 micron continuum radiation is due to an expanding wind free-free emission in an intermediate case between optically thick and optically thin regimes. The inferred mass loss rate evaluation gives ~10^{-4} Msun/yr. Our results are consistent with a Wolf-Rayet-like companion t...

Retention of 241Am and 239Pu in the rat as influenced by Triton WR 1339

International Nuclear Information System (INIS)

Gruner, R.; Siedel, A.

1976-01-01

A lysosomotropic agent, the non-ionic detergent Triton WR 1339 (a poly-oxyethylene ether of formaldehyde polymers of octylphenol) is known to be stored in rat liver lysosomes. The results of a study made to determine whether Triton WR 1339 exerts an influence on the metabolic fate of monomeric 239 Pu and 241 Am in the rat as well as on the removal of these nuclides by DTPA, since Triton WR 1339 and transuranic elements share the same deposition site, are reported. The influence of Triton WR 1339 on the 241 Am content (per cent of 241 Am dose) of rat organs (skeleton, liver, kidneys) at different times after Triton WR 1339 injection, the influence of the time of Triton WR 1339 injection on the 241 Am content (per cent of 241 Am dose) of the same rat organs, and the influence of Triton WR 1339 Zn-DTPA and the combination of them on the retention of monomeric 239 Pu in the same rat organs (per cent of 239 Pu dose), are shown in tabular form. The mechanism whereby Triton WR 1339 appears to shorten the biological half-life of 239 Pu and 241 Am in rat liver is discussed. (U.K.)

Topical or systemic 16,16 dm prostaglandin E2 or WR-2721 (WR-1065) protects mice from alopecia after fractionated irradiation

International Nuclear Information System (INIS)

Geng, L.; Malkinson, F.D.; Hanson, W.R.

1992-01-01

Previous studies in mice demonstrated that systemic or topical 16,16 dm PGE 2 protected against single dose radiation-induced hair loss. The authors have now investigated prostaglandin, or WR-2721, protection against murine alopecia produced by varying doses and schedules of fractionated radiation. In some studies with the radioprotectors given systematically, WR-2721 afforded slightly greater radioprotection than 16,16 dm PGE 2 . The two compounds were essentially equally radioprotective in the topical application studies. Since both systemic and topical applications of the agents tested enhanced hair regrowth following radiation, the authors conclude that clinical use of these compounds may provide some protection of hair follicles, and perhaps other tissues, lying within a radiation therapy field. (author)

Depletion of glutathione by the radioprotective agent S-2-(3-aminopropylamino)ethyl phosphorothioic acid (WR2721)

International Nuclear Information System (INIS)

Schor, N.F.

1989-01-01

S-2-(3-Aminopropylamino)ethyl phosphorothioic acid (WR2721) is a free radical scavenger currently in limited clinical use as an adjunct in cancer radio- and chemotherapy. We have previously determined the pharmacokinetics and protein binding characteristics of WR2721 in rabbits and in humans. We have also shown that WR2721 is an effective mucolytic agent in patients with cystic fibrosis. In vivo, WR2721 is converted to its free thiol analogue, N-2-mercaptoethyl-1,3-diaminopropane (MDP), and, as such, reacts with disulfide bonds in the mucin molecule, altering its rheology. In the course of experiments designed to examine the spectrum of its activity as a free radical scavenger, we have observed that WR2721 exacerbates the toxicity of those free radical-generating agents, such as acetaminophen and 6-hydroxydopamine, which depend upon glutathione for their detoxication. For this reason, we examined the glutathione content of the livers of mice treated with WR2721. (author)

Colliding winds: Interaction regions with strong heat conduction

International Nuclear Information System (INIS)

Imamura, J.N.; Chevalier, R.A.

1984-01-01

The interaction of fast stellar wind with a slower wind from previous mass loss gives rise to a region of hot, shocked gas. We obtain self-similar solutions for the interaction region under the assumptions of constant mass loss rate and wind velocity for the two winds, conversion of energy in the shock region, and either isothermal electrons and adiabatic ions or isothermal electrons ad ions in the shocked region. The isothermal assumption is intended to show the effects of strog heat conduction. The solutions have no heat conduction through the shock waves and assume that the electron and ion temperatures are equilibriated in the shock waves. The one-temperature isothermal solutions have nearly constant density through the shocked region, while the two-temperature solutions are intermediate between the one-temperature adiabatic and isothermal solutions. In the two-temperature solutions, the ion temperature goes to zero at the point where the gas comoves with the shocked region and the density peaks at this point. The solution may qualitatively describe the effects of heat conduction on interaction regions in the solar wind. It will be important to determine whether the assumption of no thermal waves outside the shocked region applies to shock waves in the solar wind

WR 148: identifying the companion of an extreme runaway massive binary*

Science.gov (United States)

Munoz, Melissa; Moffat, Anthony F. J.; Hill, Grant M.; Shenar, Tomer; Richardson, Noel D.; Pablo, Herbert; St-Louis, Nicole; Ramiaramanantsoa, Tahina

2017-05-01

WR 148 (HD 197406) is an extreme runaway system considered to be a potential candidate for a short-period (4.3173 d) rare WR + compact object binary. Provided with new high-resolution, high signal-to-noise spectra from the Keck observatory, we determine the orbital parameters for both the primary WR and the secondary, yielding respective projected orbital velocity amplitudes of 88.1 ± 3.8 km s-1 and 79.2 ± 3.1 km s-1 and implying a mass ratio of 1.1 ± 0.1. We then apply the shift-and-add technique to disentangle the spectra and obtain spectra compatible with a WN7ha and an O4-6 star. Considering an orbital inclination of ˜67°, derived from previous polarimetry observations, the system's total mass would be a mere 2-3M_{⊙}, an unprecedented result for a putative massive binary system. However, a system comprising a 37 M_{⊙} secondary (typical mass of an O5V star) and a 33 M_{⊙} primary (given the mass ratio) would infer an inclination of ˜18°. We therefore reconsider the previous methods of deriving the orbital inclination based on time-dependent polarimetry and photometry. While the polarimetric results are inconclusive requiring better data, the photometric results favour low inclinations. Finally, we compute WR 148's space velocity and retrace the runaway's trajectory back to the Galactic plane (GP). With an ejection velocity of 198 ± 27 km s-1 and a travel time of 4.7 ± 0.8 Myr to reach its current location, WR 148 was most likely ejected via dynamical interactions in a young cluster.

Astronomy in Denver: Spectropolarimetric Observations of 5 Wolf-Rayet Binary Stars with SALT/RSS

Science.gov (United States)

Fullard, Andrew; Ansary, Zyed; Azancot Luchtan, Daniel; Gallegos, Hunter; Luepker, Martin; Hoffman, Jennifer L.; Nordsieck, Kenneth H.; SALT observation team

2018-06-01

Mass loss from massive stars is an important yet poorly understood factor in shaping their evolution. Wolf-Rayet (WR) stars are of particular interest due to their stellar winds, which create large regions of circumstellar material (CSM). They are also supernova and possible gamma-ray burst (GRB) progenitors. Like other massive stars, WR stars often occur in binaries, where interaction can affect their mass loss rates and provide the rapid rotation thought to be required for GRB production. The diagnostic tool of spectropolarimetry, along with the potentially eclipsing nature of a binary system, helps us to better characterize the CSM created by the stars’ colliding winds. Thus, we can determine mass loss rates and infer rapid rotation. We present spectropolarimetric results for five WR+O eclipsing binary systems, obtained with the Robert Stobie Spectrograph at the South African Large Telescope, between April 2017 and April 2018. The data allow us to map both continuum and emission line polarization variations with phase, which constrains where different CSM components scatter light in the systems. We discuss our initial findings and interpretations of the polarimetric variability in each binary system, and compare the systems.

A CHANDRA OBSERVATION OF THE ECLIPSING WOLF-RAYET BINARY CQ Cep

Energy Technology Data Exchange (ETDEWEB)

Skinner, Stephen L. [CASA, Univ. of Colorado, Boulder, CO 80309-0389 (United States); Zhekov, Svetozar A. [Space Research and Technology Institute, Akad. G. Bonchev Str., Sofia, 1113 (Bulgaria); Güdel, Manuel [Dept. of Astrophysics, Univ. of Vienna, Türkenschanzstr. 17, A-1180 Vienna (Austria); Schmutz, Werner, E-mail: stephen.skinner@colorado.edu, E-mail: szhekov@space.bas.bg, E-mail: manuel.guedel@univie.ac.at, E-mail: werner.schmutz@pmodwrc.ch [Physikalisch-Meteorologisches Observatorium Davos and World Radiation Center (PMOD/WRC), Dorfstrasse 33, CH-7260 Davos Dorf (Switzerland)

2015-02-01

The short-period (1.64 d) near-contact eclipsing WN6+O9 binary system CQ Cep provides an ideal laboratory for testing the predictions of X-ray colliding wind shock theory at close separation where the winds may not have reached terminal speeds before colliding. We present results of a Chandra X-ray observation of CQ Cep spanning ∼1 day during which a simultaneous Chandra optical light curve was acquired. Our primary objective was to compare the observed X-ray properties with colliding wind shock theory, which predicts that the hottest shock plasma (T ≳ 20 MK) will form on or near the line-of-centers between the stars. The X-ray spectrum is strikingly similar to apparently single WN6 stars such as WR 134 and spectral lines reveal plasma over a broad range of temperatures T ∼ 4-40 MK. A deep optical eclipse was seen as the O star passed in front of the Wolf-Rayet star and we determine an orbital period P {sub orb} = 1.6412400 d. Somewhat surprisingly, no significant X-ray variability was detected. This implies that the hottest X-ray plasma is not confined to the region between the stars, at odds with the colliding wind picture and suggesting that other X-ray production mechanisms may be at work. Hydrodynamic simulations that account for such effects as radiative cooling and orbital motion will be needed to determine if the new Chandra results can be reconciled with the colliding wind picture.

Destination Universe: The Incredible Journey of a Proton in the Large Hadron Collider

CERN Multimedia

Lefevre, C

2008-01-01

This brochure illustrates the incredible journey of a proton as he winds his way through the CERN accelerator chain and ends up inside the Large Hadron Collider (LHC). The LHC is CERN's flagship particle accelerator which can collide protons together at close to the speed of light, creating circumstances like those just seconds after the Big Bang.

Further studies on selective radioprotection by organic zinc salts and synergism of zinc aspartate with WR 2721

International Nuclear Information System (INIS)

Floersheim, G.L.; Bieri, A.

1990-01-01

Protection of the haematocrit and thrombocytes by small doses of the aminothiol radioprotector WR 2721 was markedly improved by the concomitant administration of small doses of zinc aspartate. Zinc aspartate was the only one of the tested zinc salts not inhibiting the regression induced by radiotherapy of human tumours grown as xenografts in immunosuppressed mice. This also applied to zinc aspartate with WR 2721. A dose of zinc aspartate which afforded synergistic haematological protection did not enhance the toxicity of WR 2721. The synergism of zinc aspartate with WR 2721 and the differential radioprotection of the combined protocol may make it possible in clinical cancer radiotherapy to obtain selective radioprotection at a lower toxicity giving an improved therapeutic ratio compared with WR 2721 alone. (author)

Topical or systemic 16,16 dm prostaglandin E sub 2 or WR-2721 (WR-1065) protects mice from alopecia after fractionated irradiation

Energy Technology Data Exchange (ETDEWEB)

Geng, L.; Malkinson, F.D. (Rush-Presbyterian-St. Luke' s Medical Center, Chicago, IL (United States)); Hanson, W.R. (Hines VA Medical Center, IL (United States))

1992-04-01

Previous studies in mice demonstrated that systemic or topical 16,16 dm PGE{sub 2} protected against single dose radiation-induced hair loss. The authors have now investigated prostaglandin, or WR-2721, protection against murine alopecia produced by varying doses and schedules of fractionated radiation. In some studies with the radioprotectors given systematically, WR-2721 afforded slightly greater radioprotection than 16,16 dm PGE{sub 2}. The two compounds were essentially equally radioprotective in the topical application studies. Since both systemic and topical applications of the agents tested enhanced hair regrowth following radiation, the authors conclude that clinical use of these compounds may provide some protection of hair follicles, and perhaps other tissues, lying within a radiation therapy field. (author).

Effects of daily treatment with a radioprotector WR-2721 on Ehrlich's ascites tumors in mice

International Nuclear Information System (INIS)

Ikebuchi, Makoto; Shinohara, Shigeo; Kimura, Hiroshi; Morimoto, Kunio; Shima, Akihiro

1981-01-01

Mice were injected daily with a radioprotector WR-2721 (S-2-[3-aminopropyl-amino]ethylphosphorothioic acid) after inoculation with Ehrlich's ascites tumor cells. Increases in weight of mice, volume of ascitic fluid and number of ascitic cells per mouse were reduced by the daily administration of 5 mg/mouse of the drug, indicating a suppressive effect of WR-2721 on growth of ascitic cells. But daily treatment with 5 mg/mouse of WR-2721 caused earlier death of tumor-bearing mice. (author)

Adaptive-Wall Wind-Tunnel Investigations

Science.gov (United States)

1981-02-01

December 1976 (University *AEDC-TR-79-55, November 1979 Microfilms No. 77-10777) 19. Sears, W.R. "Adaptive Wind Tunnels with 37. Ilrdelyi, A., Magnus , W...California Institute of Technology General Dynamics-CONVAIR Pasadena, CA 91109 P. O. Box 1128 San Diego, CA 92112 Mr. L. I. Chases , MUG-MD Lib. General...Electric Company Dr. R. Magnus Missile and Space Division General Dynamics-CONVAIR P. 0. Box 8555 Kearny Mesa Plant Philadelphia, PA 19101 P. 0. Box

A Numerical Procedure for Analysis of W/R Contact Using Explicit Finite Element Methods

NARCIS (Netherlands)

Ma, Y.; Markine, V.L.

2015-01-01

Since no effective experimental approaches have been proposed to assess wheel and rail (W/R) contact performance till now, numerical computational analysis is known as an alternative to approximately simulate the W/R interaction. In this paper, one numerical procedure is proposed on the basis of

Chemoprotection against fractionated radiation exposures with WR-2721: skin injury

International Nuclear Information System (INIS)

Echols, F.S.; Yuhas, J.M.

1976-01-01

These studies extend the analysis of the potential application of WR-2721 [S-2-(3-aminopropylamino)ethylphosphorothioic acid] to radiation therapy by determining the ability of the drug to protect mice against hair loss induced by multiple exposures to radiation. In the two mouse strains tested, RFM and BALB/c, the relatively low drug dose used (200 mg/kg) protected the mice against hair loss from single exposures by factors of 1.67 and 1.73. The dose necessary to produce a given level of hair loss (ED 50 ) increases with increasing number of fractions. The ED 50 increases as N/sup 0.52/ and N/sup 0.59/ in the two strains of mice when they are not drug-treated, but as N/sup 0.39/ and N/sup 0.50/ in mice that are drug-treated. Thus, the protective effectiveness of WR-2721 decreases with increasing numbers of fractions, but the drug is still able to give a dose-modifying factor of about 1.25 when the total exposure is given as a series of 9 or 10 fractions. WR-2721 appears to offer the possibility of improving the efficiency of radiotherapy under clinical conditions

Circumvention of the tumor membrane barrier to WR-2721 absorption by reduction of drug hydrophilicity

International Nuclear Information System (INIS)

Yuhas, J.M.; Davis, M.E.; Glover, D.; Brown, D.Q.; Ritter, M.

1982-01-01

In attempting to account for the ability of most solid tumors to restrict the absorption of WR-2721, aminopropyl-aminoethylphosphorothioate, we examined a number of drug characteristics which might allow for this restriction, and observed that drug hypdrophilicity was a major contributing factor. When the highly hydrophilic WR-2721 was dephosphorylated, the drug became less hydrophilic and could readily cross tumor cell membranes. In addition, conventional radioprotectants, such as cysteine and mercaptoethylamine, were shown to be less hydrophilic than WR-2721 and also to cross tumor membranes readily. Therefore, drug hydrophilicity would appear to be the factor underlying the ability of WR-2721 to selectively protect normal tissues while most other protectors alter the radiation resistance of normal and tumor tissue alike. A red blood cell model for studying this problem in greater detail is described

Destination Universe: The Incredible Journey of a Proton in the Large Hadron Collider (English version)

CERN Multimedia

Lefevre, C

2008-01-01

This brochure illustrates the incredible journey of a proton as he winds his way through the CERN accelerator chain and ends up inside the Large Hadron Collider (LHC). The LHC is CERN's flagship particle accelerator which can collide protons together at close to the speed of light, creating circumstances like those just seconds after the Big Bang.

Colliders

CERN Document Server

Chou, Weiren

2014-01-01

The idea of colliding two particle beams to fully exploit the energy of accelerated particles was first proposed by Rolf Wideröe, who in 1943 applied for a patent on the collider concept and was awarded the patent in 1953. The first three colliders — AdA in Italy, CBX in the US, and VEP-1 in the then Soviet Union — came to operation about 50 years ago in the mid-1960s. A number of other colliders followed. Over the past decades, colliders defined the energy frontier in particle physics. Different types of colliers — proton–proton, proton–antiproton, electron–positron, electron–proton, electron-ion and ion-ion colliders — have played complementary roles in fully mapping out the constituents and forces in the Standard Model (SM). We are now at a point where all predicted SM constituents of matter and forces have been found, and all the latest ones were found at colliders. Colliders also play a critical role in advancing beam physics, accelerator research and technology development. It is timel...

Inhibition of topoisomerase IIα activity in CHO K1 cells by 2-[(aminopropyl)amino]ethanethiol (WR-1065)

International Nuclear Information System (INIS)

Grdina, D.J.

1993-06-01

The aminothiol 2-[(aminopropyl)amino]ethanethiol (WR-1065) is the active thiol of the clinically studied radioprotective agent S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721). WR-1065 is an effective radiation protector and antimutagenic agent when it is administered 30 min prior to radiation exposure to Chinese hamster ovary Kl cells at a concentration of 4 mM. Under these exposure conditions, topoisomerase (topo) I and II activities and associated protein contents were measured in the K1 cell line using the DNA relaxation assay, the P4 unknotting assay, and immunoblotting, respectively. WR-1065 was ineffective in modifying topo I activity, but it did reduce topo IIa activity by an average of 50 percent. The magnitude of topo IIa protein content, however, was not affected by these exposure conditions. Cell cycle effects were monitored by the method of flow cytometry. Exposure of cells to 4 mM WR-1065 for a period of up to 6 h resulted in a buildup of cells in the G2 compartment. However, in contrast to topo II inhibitors used in chemotherapy, WR-1065 is an effective radioprotector agent capable of protecting against both radiation-induced cell lethality and mutagenesis. One of several mechanisms of radiation protection attributed to aminothiol compounds such as WR-1065 has been their ability to affect endogenous enzymatic reactions involved in DNA synthesis, repair, and cell cycle progression. These results are consistent with such a proposed mechanism and demonstrate in particular a modifying effect by 2-[(aminopropyl)amino]ethanethiol on type II topoisomerase, which is involved in DNA synthesis

Comment on "Polarized window for left-right symmetry and a right-handed neutrino at the Large Hadron-Electron Collider"

Science.gov (United States)

Queiroz, Farinaldo S.

2016-06-01

Reference [1 S. Mondal and S. K. Rai, Phys. Rev. D 93, 011702 (2016).] recently argued that the projected Large Hadron Electron Collider (LHeC) presents a unique opportunity to discover a left-right symmetry since the LHeC has availability for polarized electrons. In particular, the authors apply some basic pT cuts on the jets and claim that the on-shell production of right-handed neutrinos at the LHeC, which violates lepton number in two units, has practically no standard model background and, therefore, that the right-handed nature of WR interactions that are intrinsic to left-right symmetric models can be confirmed by using colliding beams consisting of an 80% polarized electron and a 7 TeV proton. In this Comment, we show that their findings, as presented, have vastly underestimated the SM background which prevents a Left-Right symmetry signal from being seen at the LHeC.

Influence of WR-2721 on metastatic tumor spread after irradiation

International Nuclear Information System (INIS)

Ullrich, R.L.; Jernigan, M.C.; Yuhas, J.M.

1975-01-01

The Line 1 alveolar cell carcinoma is a transplantable murine tumor which, unlike most others, kills the host by means of metastatic spread. Attempts to cure this tumor with localized radiation therapy often fail, in spite of local tumor control, because the metastases evade the treatment. These facts suggest that host-tumor interactions may play a particularly important role in determining the ultimate survival of the tumor bearing animal. In order to initially evaluate the possible importance of normal regional tissues in host-tumor interactions the influence of WR-2721, a radioprotective drug, was examined for local tumor control and subsequent survival of the tumor bearing animal after localized radiation. Results indicated that WR-2721 can decrease metastasis. (U.S.)

Inhibition of topoisomerase II{alpha} activity in CHO K1 cells by 2-[(aminopropyl)amino]ethanethiol (WR-1065)

Energy Technology Data Exchange (ETDEWEB)

Grdina, D.J. [Argonne National Lab., IL (United States)]|[Chicago Univ., IL (United States). Dept. of Radiation and Cellular Oncology; Constantinou, A. [Illinois Univ., Chicago, IL (United States). Specialized Cancer Center; Shigematsu, N.; Murley, J.S. [Argonne National Lab., IL (United States)

1993-06-01

The aminothiol 2-[(aminopropyl)amino]ethanethiol (WR-1065) is the active thiol of the clinically studied radioprotective agent S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721). WR-1065 is an effective radiation protector and antimutagenic agent when it is administered 30 min prior to radiation exposure to Chinese hamster ovary Kl cells at a concentration of 4 mM. Under these exposure conditions, topoisomerase (topo) I and II activities and associated protein contents were measured in the K1 cell line using the DNA relaxation assay, the P4 unknotting assay, and immunoblotting, respectively. WR-1065 was ineffective in modifying topo I activity, but it did reduce topo IIa activity by an average of 50 percent. The magnitude of topo IIa protein content, however, was not affected by these exposure conditions. Cell cycle effects were monitored by the method of flow cytometry. Exposure of cells to 4 mM WR-1065 for a period of up to 6 h resulted in a buildup of cells in the G2 compartment. However, in contrast to topo II inhibitors used in chemotherapy, WR-1065 is an effective radioprotector agent capable of protecting against both radiation-induced cell lethality and mutagenesis. One of several mechanisms of radiation protection attributed to aminothiol compounds such as WR-1065 has been their ability to affect endogenous enzymatic reactions involved in DNA synthesis, repair, and cell cycle progression. These results are consistent with such a proposed mechanism and demonstrate in particular a modifying effect by 2-[(aminopropyl)amino]ethanethiol on type II topoisomerase, which is involved in DNA synthesis.

WR 143: A Wolf-Rayet Binary

OpenAIRE

Varricatt, Watson P.; Ashok, Nagarhalli M.

2005-01-01

Near infrared spectroscopy and photometry of the Wolf-Rayet Star WR 143 (HD 195177) were obtained in the $JHK$ photometric bands. High resolution spectra observed in the J and H bands exhibit narrow 1.083-micron He I line and the H I Pa Beta and the Brackett series lines in emission superposed on the broad emission line spectrum of the Wolf-Rayet star, giving strong indications of the presence of a companion. From the narrow emission lines observed, the companion is identified to be an early-...

Enhancement of protective action of radioprotector; Mogucnosti potenciranja zastitnog dejstva radioprotektora WR-2721

Energy Technology Data Exchange (ETDEWEB)

Dobric, S; Milovanovic, S [Vojnotehnicki Institut, Belgrade (Yugoslavia)

1996-12-31

The efficacy of radioprotector WR-2721 (300 mg/kg ip, 20 min before irradiation), alone or in combination with an extract of Ginkgo biloba (Tebonin{sup R}) (17.5 mg/kg ip, 20 min before, and then 1 hr and 24 hr after irradiation), an extract of thymus (Thymolip{sup R}) (10 mg/kg sc, 24 hr before and 15 min after irradiation), herbal mitogen agrostemin (0.1 mg/kg ip. 24 before and immediately after irradiation) and calcium antagonist verapamil (1 mg/kg ip, immediately before irradiation), was studied in adult male Wistar rats irradiated by 9 Gy and 12 Gy of X-rays. It was established that above mentioned compounds, except wr-2721, failed to protect irradiated animals. Given in combination with WR-2721 only agrostemin and verapamil enhanced the efficacy of the protector. The combination with verapamil was more effective providing protection even in supralethal irradiated rats. (author) 7 refs. 2 tabs.

Improved HPLC assay for S-2-(3-aminopropylamino)ethyl phosphorothioate (WR-2721) in plasma

International Nuclear Information System (INIS)

Swynnerton, N.F.; McGovern, E.P.; Nino, J.A.; Mangold, D.J.

1984-01-01

An HPLC assay is presented for the detection and quantitation of the radioprotective drug S-2-(3-aminopropylamino)ethyl phosphorothioate (WR-2721, ethiofos) present in plasma. Improved selectivity and a 40-fold increase in sensitivity have been demonstrated over the method previously reported by this laboratory. Using precolumn derivatization with fluorescamine and S-3-(4-aminobutylamino)propyl phosphorothioate (WR-80855, a homolog of WR-2721) as the internal standard, drug levels of 0.05 to 1000 μg/mL were determined with excellent precision. Detector response was linear over the entire range. The assay uses 150 μL of plasma and requires a total chromatography time of about 50 minutes. The method was found suitable for pharmacokinetic studies in a preliminary experiment with a beagle dog in which no interferences due to plasma constituents or drug metabolites were observed

The WR-1 corrosion test facility

International Nuclear Information System (INIS)

Murphy, E.V.; Simmons, G.R.

1978-07-01

This report describes a new Corrosion Test Facility which has recently been installed in the WR-1 organic-cooled research reactor. The irradiation facility is a single insert, installed in a reactor site, which can deliver a fast neutron flux density of 2.65 x 10 17 neutrons/(m 2 .s) to specimens under irradiation. A self-contained controlled-chemistry cooling water circuit removes the gamma- and neutron-heat generated in the insert and specimens. Specimen temperatures typically vary from 245 deg C to 280 deg C across the insert core region. (author)

Hypolipidemic action of chrysin on Triton WR-1339-induced hyperlipidemia in female C57BL/6 mice

Directory of Open Access Journals (Sweden)

Micheli Stéfani Zarzecki

2014-01-01

Full Text Available Chrysin (5,7-dihydroxyflavone is a flavonoid, natural component of traditional medicinal herbs, present in honey, propolis and many plant extracts. The objective of this study was to investigate the hypolipidemic properties of chrysin on Triton WR-1339-induced hyperlipidemia in female C57BL/6 mice. Triton WR-1339 was administered intraperitoneally (400 mg/kg to overnight-fasted mice to develop acute hyperlipidemia. Chrysin was administered orally (10 mg/kg 30 min before Triton WR-1339. At 24 h after Triton WR-1339 injection, blood samples were collected to measure plasma lipid levels. The hepatic thiobarbituric acid reactive substances (TBARS, carbonyl content, non-protein sulfhydryl (NPSH and ascorbic acid (AA levels, as well as catalase (CAT and superoxide dismutase (SOD activity were recorded. Chrysin administration significantly decreased total cholesterol levels. In addition, it partially decreased non-high density lipoprotein-cholesterol and triglycerides levels in plasma of hyperlipidaemic mice. In addition chrysin administration prevented the increase on TBARS levels and prevented the decrease in SOD activity induced by Triton WR-1339. These findings indicated that chrysin was able to decrease plasma lipids concentration and that its antioxidant properties was, at least in part, involved in the hypolipidaemic action of chrysin.

Effect of the radioprotector WR 2721 on the response of metastatic Lewis lung carcinoma colonies to alkylating agents

International Nuclear Information System (INIS)

Wist, E.A.

1985-01-01

WR 2721 protected ''artificial'' lung metastases of Lewis lung carcinoma against the cytotoxic effects of cyclophosphamide and melphalan. When mice were pretreated with WR 2721 30 min before exposure to the alkylating agents a significant increase in the number of lung metastases could be observed. This protection of micrometastases had a significant impact on survival in the case of cyclophosphamide treatment, but not in the case of melphalan treatment. The degree of protection at a standard dose of WR 2721 was dose dependent. (orig.)

Spectral Identification of New Galactic cLBV and WR Stars

Science.gov (United States)

Stringfellow, G. S.; Gvaramadze, V. V.; Beletsky, Y.; Kniazev, A. Y.

2012-12-01

We have undertaken a near-IR spectral survey of stars associated with compact nebulae recently revealed by the Spitzer and WISE imaging surveys. These circumstellar nebulae, produced by massive evolved stars, display a variety of symmetries and shapes and are often only evident at mid-IR wavelengths. Stars associated with ˜50 of these nebulae have been observed. We also obtained recent spectra of previously confirmed (known) luminous blue variables (LBVs) and candidate LBVs (cLBVs). The spectral similarity of the stars observed when compared directly to known LBVs and Wolf-Rayet (WR) stars indicate many are newly identified cLBVs, with a few being newly discovered WR stars, mostly of WN8-9h spectral type. These results suggest that a large population of previously unidentified cLBVs and related transitional stars reside in the Galaxy and confirm that circumstellar nebulae are inherent to most (c)LBVs.

Protective effect of WR-2823 in irradiated mice

International Nuclear Information System (INIS)

Milovanovicj, A.; Tanasijevicj, D.; Cvetkovicj, M.; Cjosicj, M.; Chizmicj, Z.

1987-01-01

A chemical compound named WR-2823 has been synthetised. The acute toxicity after IP application has been investigated and LD 50 estimated. The protective ability of the radioprotector has been investigated in mice with gamma rays of 60 Co, or at the origin of 252 Cf. High protective potency in mice, treated with lethal doses of gamma rays and neutrons have been estimated. (author) 8 refs.; 1 tab

A NEAR-INFRARED SURVEY OF THE INNER GALACTIC PLANE FOR WOLF-RAYET STARS. I. METHODS AND FIRST RESULTS: 41 NEW WR STARS

International Nuclear Information System (INIS)

Shara, Michael M.; Gerke, Jill; Zurek, David; Moffat, Anthony F. J.; Doyon, Rene; Villar-Sbaffi, Alfredo; Stanonik, Kathryn; Artigau, Etienne; Drissen, Laurent

2009-01-01

The discovery of new Wolf-Rayet (WR) stars in our Galaxy via large-scale narrowband optical surveys has been severely limited by dust extinction. Recent improvements in infrared technology have made narrowband-broadband imaging surveys viable again. We report a new J, K, and narrowband imaging survey of 300 deg 2 of the plane of the Galaxy, spanning 150 degrees in Galactic longitude and reaching 1 degree above and below the Galactic plane. The survey has a useful limiting magnitude of K = 15 over most of the observed Galactic plane, and K = 14 within a few degrees of the Galactic center. Thousands of emission line candidates have been detected. In spectrographic follow-ups of 173 WR star candidates we have discovered 41 new WR stars, 15 of type WN and 26 of type WC. Star subtype assignments have been confirmed with K-band spectra, and distances approximated using the method of spectroscopic parallax. A few of the new WR stars are among the most distant known in our Galaxy. The distribution of these new WR stars is seen to follow that of previously known WR stars along the spiral arms of the Galaxy. Tentative radial velocities were also measured for most of the new WR stars.

Development of polarized beam conversion system for the linear collider complex

International Nuclear Information System (INIS)

Viilleval'd, G.S.; Vsevolozhskaya, T.A.; Karasyuk, V.N.; Sil'vestrov, G.I.; Chernyakin, A.D.

1983-01-01

Results of development of the polarized beam conversion system for the 150 GeV linear collider aiming at the linear collider operation with a high repetition rate (approximately 10 Hz), are presented. It is shown, that the conversion can be realized by means of ondulator radiation. Structurally, the spiral ondulator is two identical solenoids, inserted in each other in such a way, that their winding turns are alternating in the direction along the axis and they are supplied by countercurrents. The main parameters of the ondulator are as follows : winding pitch -0.7 cm, the ondulator length 150 m. For generation a field of the intensity 5 kOe it has been suggested that solenoids should be supplied by sinusoidal pulse current of duration approximately 200 μs. It is shown, that the introduction of iron into solenoid increases the efficiency by a factor of 2.1 and 2.7 in the ondulator with iron only in interloop gaps and with the addition of iron locking magnetic counterflow

Muon colliders

International Nuclear Information System (INIS)

Cline, David

1995-01-01

The increasing interest in the possibility of positive-negative muon colliders was reflected in the second workshop on the Physics Potential and Development of Muon Colliders, held in Sausalito, California, from 16-19 November, with some 60 attendees. It began with an overview of the particle physics goals, detector constraints, the muon collider and mu cooling, and source issues. The major issue confronting muon development is the possible luminosity achievable. Two collider energies were considered: 200 + 200 GeV and 2 + 2 TeV. The major particle physics goals are the detection of the higgs boson(s) for the lower energy collider, together with WW scattering and supersymmetric particle discovery. At the first such workshop, held in Napa, California, in 1992, it was estimated that a luminosity of some 10 30 and 3 x 10 32 cm -2 s -1 for the low and high energy collider might be achieved (papers from this meeting were published in the October issue of NIM). This was considered a somewhat conservative estimate at the time. At the Sausalito workshop the goal was to see if a luminosity of 10 32 to 10 34 for the two colliders might be achievable and usable by a detector. There were five working groups - physics, 200 + 200 GeV collider, 2 + 2 TeV collider, detector design and backgrounds, and muon cooling and production methods. Considerable progress was made in all these areas at the workshop.

Factors associated with bat mortality at wind energy facilities in the United States

Science.gov (United States)

Hundreds of thousands of bats are killed annually by colliding with wind turbines in the U.S., yet little is known about factors causing variation in mortality across wind energy facilities. We conducted a quantitative synthesis of bat collision mortality with wind turbines by re...

Emission Lines in the Near-infrared Spectra of the Infrared Quintuplet Stars in the Galactic Center

Energy Technology Data Exchange (ETDEWEB)

Najarro, F. [Departamento de Astrofísica, Centro de Astrobiología (CSIC-INTA), Ctra. Torrejón a Ajalvir km 4, E-28850 Torrejón de Ardoz (Spain); Geballe, T. R. [Gemini Observatory, 670 North A’ohoku Place, Hilo, HI 96720 (United States); Figer, D. F. [Center for Detectors, Rochester Institute of Technology, 74 Lomb Memorial Drive, Rochester, NY 14623 (United States); Fuente, D. de la [Instituto de Astronomía, Unidad Académica en Ensenada, Universidad Nacional Autónoma de México, Ensenada 22860, México (Mexico)

2017-08-20

We report the detection of a number of emission lines in the 1.0–2.4 μ m spectra of four of the five bright-infrared dust-embedded stars at the center of the Galactic center’s (GC) Quintuplet Cluster. Spectroscopy of the central stars of these objects is hampered not only by the large interstellar extinction that obscures all of the objects in the GC, but also by the large amounts of warm circumstellar dust surrounding each of the five stars. The pinwheel morphologies of the dust observed previously around two of them are indicative of Wolf–Rayet colliding wind binaries; however, infrared spectra of each of the five have until now revealed only dust continua steeply rising to long wavelengths and absorption lines and bands from interstellar gas and dust. The emission lines detected, from ionized carbon and from helium, are broad and confirm that the objects are dusty late-type carbon Wolf–Rayet stars.

Muon colliders

International Nuclear Information System (INIS)

Palmer, R.B.; Sessler, A.; Skrinsky, A.

1996-01-01

Muon Colliders have unique technical and physics advantages and disadvantages when compared with both hadron and electron machines. They should thus be regarded as complementary. Parameters are given of 4 TeV and 0.5 TeV high luminosity micro + micro - colliders, and of a 0.5 TeV lower luminosity demonstration machine. We discuss the various systems in such muon colliders, starting from the proton accelerator needed to generate the muons and proceeding through muon cooling, acceleration and storage in a collider ring. Problems of detector background are also discussed

Effects of area postrema lesions on taste aversions produced by treatment with WR-2721 in the rat

International Nuclear Information System (INIS)

Rabin, B.M.; Hunt, W.A.; Lee, J.

1986-01-01

The conditioned taste aversion procedure was used to further assess some behavioral effects of treatment with the putative radioprotectant WR-2721 and the role of the area postrema in mediating the behavioral effects of treatment. Treatment with 40, 150 or 300 mg/kg WR-2721 produced dose-dependent changes in sucrose intake in both control rats and rats with area postrema lesions. The effectiveness of the lesion in disrupting the acquisition of an aversion varied as a function of the dose administered, with the lesions producing the greatest disruption of aversion learning at the lowest dose and little disruption at the highest dose tested. At all dose levels, sucrose intake was greater for the rats with area postrema lesions than for the sham-operated control rats. Treatment with WR-2721 also produced significant decreases in total fluid intake, particularly at the higher dose levels. The results are discussed as indicating that treatment with WR-2721 produces highly toxic effects on behavior and that the use of the compound as a radioprotectant for radiotherapy requires additional assessment of its effects on brain function and behavior

Mass loss from Wolf-Rayet stars

International Nuclear Information System (INIS)

Willis, A.J.

1982-01-01

Recent results relating to the stellar winds and mass loss rates of the WR stars are reviewed, emphasising new data and their interpretation acquired at UV, IR and Radio wavelengths. The subject is discussed under the headings: physical and chemical properties of WR stars (effective temperatures and radiative luminosities; masses; chemical abundances); velocity, ionisation and excitation structure of WR winds; mass loss rates of WR stars; mass loss properties of WR stars in the LMC; comparisons with theoretical models of mass loss; ring nebulae around WR stars; conclusions. (author)

Protective effect of S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721) on irradiation-induced inhibition of intestinal transport function

International Nuclear Information System (INIS)

Chen, T.S.; Ando, M.

1983-01-01

The purpose of this study was to investigate the protective effect of S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721) on whole-body irradiation-induced inhibition of intestinal transport function. The jejunal transport of fluid and sugars was studied in male Swiss-Webster mice before and 3 days after whole-body irradiation (1000 rads). The rates of glucose and water transport were decreased by 86 and 70%, respectively, in irradiated animals. However, the rate of transport of 3-O-methyl-D-glucose (3MG) was not affected. In mice receiving WR-2721 (500 mg/kg, ip) 15 to 30 min prior to whole-body irradiation, net water flux was unaffected and the rate of D-glucose transport was decreased only 8%. WR-2721 administered alone (500 mg/kg, ip) had no effect on either D-glucose transport or net water flux across the jejunal mucosa. The results suggest that WR-2721 protects against irradiation-induced inhibition of some intestinal transport functions

Cisplatin neuropathy. Risk factors, prognosis, and protection by WR-2721

International Nuclear Information System (INIS)

Mollman, J.E.; Glover, D.J.; Hogan, W.M.; Furman, R.E.

1988-01-01

A prospective study of patients receiving cis-diaminedichloroplatin II (DDP) was carried out to determine if risk factors could be identified related to the patient's living habits or past medical history that would predict in which patients DDP neuropathy might develop. Sixty-nine patients receiving six different combinations of chemotherapeutic agents, including DDP were examined. Twenty-eight of these patients received DDP in combination with the radioprotective agent S-2-(3-aminopropylamino)-ethylphosporothioic acid (WR 2721). No risk factors were identified relating to personal habits or past medical history of the patients. However, patients receiving DDP (40 mg/m2) on 5 consecutive days had a significantly higher incidence of neuropathy. Patients receiving DDP in combination with WR 2721 had a significantly lower incidence of neuropathy, and the mean dose at onset was significantly higher than the mean dose at onset of neuropathy for all other groups. In addition, five of six patients who were available for long-term follow-up demonstrated nearly complete reversal of the signs and symptoms of neuropathy

Effects of WR1065 on 6-hydroxydopamine-induced motor imbalance: Possible involvement of oxidative stress and inflammatory cytokines.

Science.gov (United States)

Kheradmand, Afshin; Nayebi, Alireza M; Jorjani, Masoumeh; Khalifeh, Solmaz; Haddadi, Rasool

2016-08-03

Over production of reactive oxygen species (ROS) is postulated to be the main contributor in degeneration of nigrostriatal dopaminergic neurons. In this study we investigated the effects of WR1065, a free radical scavenger, on motor imbalance, oxidative stress parameters and inflammatory cytokines in CSF and brain of hemi-parkinsonian rats. Lesion of dopaminergic neurons was done by unilateral infusion of 6-hydroxydopamine into the central region of the substentia nigra pars compacta (SNc) to induce hemi-parkinsonism and motor imbalance in rats. WR1065 (20, 40 and 80μg/2μl/rat) was administered three days before 6-OHDA administration. After three weeks behavioral study was performed and then brain and CSF samples were collected to assess tumor necrosis factor (TNFα), interlukin (IL-1β), reduced glutathione (GSH), and malondialdehyde (MDA). WR1065 pre-treatment in rats before receiving 6-OHDA, improved significantly motor impairment and caused reduction of MDA and inflammatory cytokines TNFα and IL-1β levels, while GSH level significantly increased when compared with lesioned rats. Our study indicated that WR1065 could improve 6-OHDA-induced motor imbalance. Furthermore, it decreased lipid peroxidation and inflammatory cytokines and restored the level of GSH up to normal range. We suggest that WR1065 can be proposed as a potential neuroprotective agent in motor impairments of PD. However to prove this hypothesis more clinical trial studies should be done. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

A NEAR-INFRARED SURVEY OF THE INNER GALACTIC PLANE FOR WOLF-RAYET STARS. II. GOING FAINTER: 71 MORE NEW W-R STARS

Energy Technology Data Exchange (ETDEWEB)

Shara, Michael M.; Faherty, Jacqueline K.; Zurek, David [American Museum of Natural History, 79th Street and Central Park West, New York, NY 10024-5192 (United States); Moffat, Anthony F. J.; Doyon, Rene [Departement de Physique, Universite de Montreal, CP 6128, Succ. C-V, Montreal, QC, H3C 3J7 (Canada); Gerke, Jill [Department of Astronomy, Ohio State University, Columbus, OH 43210-1173 (United States); Artigau, Etienne; Drissen, Laurent, E-mail: mshara@amnh.org, E-mail: jfaherty@amnh.org, E-mail: dzurek@amnh.org, E-mail: moffat@astro.umontreal.ca, E-mail: doyon@astro.umontreal.ca, E-mail: gerke@astronomy.ohio-state.edu, E-mail: artigau@astro.umontreal.ca, E-mail: ldrissen@phy.ulaval.ca [Departement de Physique, Universite Laval, Pavillon Vachon, Quebec City, QC, G1K 7P4 (Canada)

2012-06-15

We are continuing a J, K and narrowband imaging survey of 300 deg{sup 2} of the plane of the Galaxy, searching for new Wolf-Rayet (W-R) stars. Our survey spans 150 Degree-Sign in Galactic longitude and reaches 1 Degree-Sign above and below the Galactic plane. The survey has a useful limiting magnitude of K = 15 over most of the observed Galactic plane, and K = 14 (due to severe crowding) within a few degrees of the Galactic center. Thousands of emission-line candidates have been detected. In spectrographic follow-ups of 146 relatively bright W-R star candidates, we have re-examined 11 previously known WC and WN stars and discovered 71 new W-R stars, 17 of type WN and 54 of type WC. Our latest image analysis pipeline now picks out W-R stars with a 57% success rate. Star subtype assignments have been confirmed with the K-band spectra and distances approximated using the method of spectroscopic parallax. Some of the new W-R stars are among the most distant known in our Galaxy. The distribution of these new W-R stars is beginning to trace the locations of massive stars along the distant spiral arms of the Milky Way.

A NEAR-INFRARED SURVEY OF THE INNER GALACTIC PLANE FOR WOLF-RAYET STARS. II. GOING FAINTER: 71 MORE NEW W-R STARS

International Nuclear Information System (INIS)

Shara, Michael M.; Faherty, Jacqueline K.; Zurek, David; Moffat, Anthony F. J.; Doyon, René; Gerke, Jill; Artigau, Etienne; Drissen, Laurent

2012-01-01

We are continuing a J, K and narrowband imaging survey of 300 deg 2 of the plane of the Galaxy, searching for new Wolf-Rayet (W-R) stars. Our survey spans 150° in Galactic longitude and reaches 1° above and below the Galactic plane. The survey has a useful limiting magnitude of K = 15 over most of the observed Galactic plane, and K = 14 (due to severe crowding) within a few degrees of the Galactic center. Thousands of emission-line candidates have been detected. In spectrographic follow-ups of 146 relatively bright W-R star candidates, we have re-examined 11 previously known WC and WN stars and discovered 71 new W-R stars, 17 of type WN and 54 of type WC. Our latest image analysis pipeline now picks out W-R stars with a 57% success rate. Star subtype assignments have been confirmed with the K-band spectra and distances approximated using the method of spectroscopic parallax. Some of the new W-R stars are among the most distant known in our Galaxy. The distribution of these new W-R stars is beginning to trace the locations of massive stars along the distant spiral arms of the Milky Way.

SSC collider quadrupole cold mass design and development

International Nuclear Information System (INIS)

Farrell, R.A.; Murray, F.S.; Jonas, P.A.; Mischler, W.R.; Blecher, L.

1992-01-01

Approximately 1,664 focussing and defocussing superconducting quadrupoles are required for the two SSC collider rings. Collider quadruple magnets (CQMS) must satisfy stringent performance, reliability, life and low cost criteria. Performance requirements include field uniformity, training, quench, tracking, thermal cycling and alignment. The CQM cold mass design presented incorporates lessons IGC and Alsthom Intermagnetics S.A. (AISA), our joint venture with GEC-Alsthom, learned in the design, development and manufacture of 500 MRI, 160 high-field custom and 126 HERA quadruple superconducting magnets. This baseline design reflects careful quantitative assessment of coil winding placement and collar material, evaluation of field uniformity and mechanical performance of the magnet coil ends using 3-D modeling and analysis, and considers tolerance and process variability. Selected CQM cold mass design highlights and a proposed prototype development program that allows incorporation of test feedback into the design to minimize risk are detailed in this paper. This information may be helpful to SSCL in the design and development of prototype CQM'S

Probing colliding Calcium plasmas with emission and VUV absorption imaging

International Nuclear Information System (INIS)

Kavanagh, K.D.; Hirsch, J.S.; Kennedy, E.T.; Costello, T.; Poletto, L.; Nicolosi, P.

2004-01-01

Full text: Laser produced plasmas are formed when a short pulse and high power laser is focused onto a surface. Applications range from VUV/X-ray sources for lithography, microscopy and radiography to X-ray lasers, thin film deposition, analytical spectroscopy and electron/ion beam generation (and even acceleration). A battery of particle and optical techniques are now used to diagnose laser plasmas. One highly successful technique is gated-CCD (Charged Coupled Device) imaging of plasma plumes. It provides critical data on the early (creation) and late (expansion) phases of plasma plumes. However, this technique is limited to detecting only the excited (emitting) species in the plume. Recently, we developed a vacuum-UV (VUV) photoabsorption imaging facility called VPIF which enables one can track the evolution of dark plume matter or non-emitting plasma species residing in ground and metastable states. Although much is known about the dynamics of single laser plasma plumes expanding freely, little is known about the overlap between colliding plasma plumes. We are currently performing combined conventional gated CCD imaging and spectroscopy with VUV absorption imaging to map the evolution of the overlap volume of two colliding and interpenetrating plasma plumes. We are specifically tracking ground state singly ionized calcium in the plasmas by tuning into the inner shell 3p to 3d transition at 33.2 eV while the excited state species are tracked using transitions in the UV -NIR spectral range. The experiment may be cast as a model system for atmospheric and/or astrophysical colliding systems, e.g., when tracer elements are injected into supersonic winds at high altitude or when supernovae eject plasma into the solar wind

Radioprotection of mouse skin by WR-2721: the critical influence of oxygen tension

International Nuclear Information System (INIS)

Denekamp, J.; Michael, B.D.; Rojas, A.; Stewart, F.A.

1982-01-01

The epidermal clone assay has been used to study the radioprotective effect of WR-2721 on mouse skin under different conditions of oxygenation and under anoxia. The skin has shown a progressive decrease in sensitivity as the inspired gas has changed from 100% oxygen towards 0% oxygen. Compared with mice breathning 100% oxygen, those breathing air are partially protected. The inspired oxygen concentration to give half the full oxygen effect is 10-12%. The radioprotecton observed with 400 mg/kg WR-2721 is markedly dependent on the ambient oxygen concentration. The protection factor is 1.1 or less in mice breathing 5%, 1% or 0% oxygen. Protection is maximal (1.95) in air and in 50% oxygen and diminishes to 1.6 at higher oxygen tensions

Physics at Future Colliders

CERN Document Server

Ellis, John R.

1999-01-01

After a brief review of the Big Issues in particle physics, we discuss the contributions to resolving that could be made by various planned and proposed future colliders. These include future runs of LEP and the Fermilab Tevatron collider, B factories, RHIC, the LHC, a linear electron-positron collider, an electron-proton collider in the LEP/LHC tunnel, a muon collider and a future larger hadron collider (FLHC). The Higgs boson and supersymmetry are used as benchmarks for assessing their capabilities. The LHC has great capacities for precision measurements as well as exploration, but also shortcomings where the complementary strengths of a linear electron-positron collider would be invaluable. It is not too soon to study seriously possible subsequent colliders.

LM1-64: a Newly Reported Lmc-Pn with WR Nucleus

Science.gov (United States)

Pena, M.; Olguin, L.; Ruiz, M. T.; Torres-Peimbert, S.

1993-05-01

The object LM1-64 was reported by Lindsay & Mullan (1963, Irish Astron. J., 5, 51) as a probable PN in the LMC. Optical and UV spectra taken by us confirm that suggestion. LM1-64 is a high excitation planetary nebulae which shows evidence of having a WC central star. Broad stellar emission at lambda 4650 is detected in the optical spectrum obtained with the CTIO 4m telescope, in 1989. A UV spectrum in the range from 1200 Angstroms to 2000 Angstroms was obtained with IUE in 1990. We have measured all the emission line fluxes available and determined values for the physical conditions and chemical abundances of the nebular ionized gas. The derived values are T(OIII) = 14000K, log He/H = 11.05, log C/H = 9.48, log O/H = 8.55 and log Ne/H = 7.94. LM1-64 shows a large C enhancement in the envelope as result of the central star activity, while He, O and Ne are comparable to the average values reported for the LMC-PNe (Monk, Barlow & Clegg, 1988, MNRAS, 234, 583). We have estimated the He II Zanstra temperature of the central star to be ~ 80,000 K. This temperature is much higher than the values reported for the known LMC-PNe with WR nucleus that Monk et al. have classified as W4 to W8. The only other high temperature WR nucleus in a LMC-PN is N66 which recently showed evidence of undergoing a WR episode (Torres-Peimbert, Ruiz, Peimbert & Pe\\ na, 1993, IAU Symp. 155, eds. A. Acker & R. Weinberger, in press).

Ion colliders

Energy Technology Data Exchange (ETDEWEB)

Fischer, W.

2011-12-01

Ion colliders are research tools for high-energy nuclear physics, and are used to test the theory of Quantum Chromo Dynamics (QCD). The collisions of fully stripped high-energy ions create matter of a temperature and density that existed only microseconds after the Big Bang. Ion colliders can reach higher densities and temperatures than fixed target experiments although at a much lower luminosity. The first ion collider was the CERN Intersecting Storage Ring (ISR), which collided light ions [77Asb1, 81Bou1]. The BNL Relativistic Heavy Ion Collider (RHIC) is in operation since 2000 and has collided a number of species at numerous energies. The CERN Large Hadron Collider (LHC) started the heavy ion program in 2010. Table 1 shows all previous and the currently planned running modes for ISR, RHIC, and LHC. All three machines also collide protons, which are spin-polarized in RHIC. Ion colliders differ from proton or antiproton colliders in a number of ways: the preparation of the ions in the source and the pre-injector chain is limited by other effects than for protons; frequent changes in the collision energy and particle species, including asymmetric species, are typical; and the interaction of ions with each other and accelerator components is different from protons, which has implications for collision products, collimation, the beam dump, and intercepting instrumentation devices such a profile monitors. In the preparation for the collider use the charge state Z of the ions is successively increased to minimize the effects of space charge, intrabeam scattering (IBS), charge change effects (electron capture and stripping), and ion-impact desorption after beam loss. Low charge states reduce space charge, intrabeam scattering, and electron capture effects. High charge states reduce electron stripping, and make bending and acceleration more effective. Electron stripping at higher energies is generally more efficient. Table 2 shows the charge states and energies in the

Ion colliders

International Nuclear Information System (INIS)

Fischer, W.

2010-01-01

Ion colliders are research tools for high-energy nuclear physics, and are used to test the theory of Quantum Chromo Dynamics (QCD). The collisions of fully stripped high-energy ions create matter of a temperature and density that existed only microseconds after the Big Bang. Ion colliders can reach higher densities and temperatures than fixed target experiments although at a much lower luminosity. The first ion collider was the CERN Intersecting Storage Ring (ISR), which collided light ions (77Asb1, 81Bou1). The BNL Relativistic Heavy Ion Collider (RHIC) is in operation since 2000 and has collided a number of species at numerous energies. The CERN Large Hadron Collider (LHC) started the heavy ion program in 2010. Table 1 shows all previous and the currently planned running modes for ISR, RHIC, and LHC. All three machines also collide protons, which are spin-polarized in RHIC. Ion colliders differ from proton or antiproton colliders in a number of ways: the preparation of the ions in the source and the pre-injector chain is limited by other effects than for protons; frequent changes in the collision energy and particle species, including asymmetric species, are typical; and the interaction of ions with each other and accelerator components is different from protons, which has implications for collision products, collimation, the beam dump, and intercepting instrumentation devices such a profile monitors. In the preparation for the collider use the charge state Z of the ions is successively increased to minimize the effects of space charge, intrabeam scattering (IBS), charge change effects (electron capture and stripping), and ion-impact desorption after beam loss. Low charge states reduce space charge, intrabeam scattering, and electron capture effects. High charge states reduce electron stripping, and make bending and acceleration more effective. Electron stripping at higher energies is generally more efficient. Table 2 shows the charge states and energies in the

PROSPECTS FOR COLLIDERS AND COLLIDER PHYSICS TO THE 1 PEV ENERGY SCALE

International Nuclear Information System (INIS)

KING, B.J.

2000-01-01

A review is given of the prospects for future colliders and collider physics at the energy frontier. A proof-of-plausibility scenario is presented for maximizing the authors progress in elementary particle physics by extending the energy reach of hadron and lepton colliders as quickly and economically as might be technically and financially feasible. The scenario comprises 5 colliders beyond the LHC--one each of e + e - and hadron colliders and three μ + μ - colliders--and is able to hold to the historical rate of progress in the log-energy reach of hadron and lepton colliders, reaching the 1 PeV constituent mass scale by the early 2040's. The technical and fiscal requirements for the feasibility of the scenario are assessed and relevant long-term R and D projects are identified. Considerations of both cost and logistics seem to strongly favor housing most or all of the colliders in the scenario in a new world high energy physics laboratory

PROSPECTS FOR COLLIDERS AND COLLIDER PHYSICS TO THE 1 PEV ENERGY SCALE

Energy Technology Data Exchange (ETDEWEB)

KING,B.J.

2000-05-05

A review is given of the prospects for future colliders and collider physics at the energy frontier. A proof-of-plausibility scenario is presented for maximizing the authors progress in elementary particle physics by extending the energy reach of hadron and lepton colliders as quickly and economically as might be technically and financially feasible. The scenario comprises 5 colliders beyond the LHC--one each of e{sup +}e{sup {minus}} and hadron colliders and three {mu}{sup +}{mu}{sup {minus}} colliders--and is able to hold to the historical rate of progress in the log-energy reach of hadron and lepton colliders, reaching the 1 PeV constituent mass scale by the early 2040's. The technical and fiscal requirements for the feasibility of the scenario are assessed and relevant long-term R and D projects are identified. Considerations of both cost and logistics seem to strongly favor housing most or all of the colliders in the scenario in a new world high energy physics laboratory.

[Sensitivity of BALB/c and WR strain mice to the immunodepressive action of cyclophosphamide and thiophosphamide].

Science.gov (United States)

Ir, K N; Telegin, L Iu; Pevnitskiĭ, L A; Malashenko, A M

1984-05-01

Experiments were made on BALB/cJ YSto and WR/Y mice to study the immunosuppressant action of cyclophosphamide (CP) and thiophosphamide (thiotepa) in vivo. WR mice were found to be significantly more sensitive to the immunosuppressant action of thiotepa than BALB/c mice and to have similar sensitivity to the action of CP. BALB/c mice appeared highly resistant to the action of both the drugs. Based on the data obtained and those reported in the literature a possible parallelism is suggested between the mutagenic and immunosuppressant action of CP and thiotepa.

Dose and time relationships of the radioprotector WR-2721 on locomotor activity in mice

International Nuclear Information System (INIS)

Landauer, M.R.; Davis, H.D.; Dominitz, J.A.; Weiss, J.F.

1987-01-01

The effects of the radioprotector S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721) on locomotor activity were evaluated in CD2F1 male mice. Separate groups of animals (N = 10/group) received an IP injection of vehicle, 25, 50, 100, 200, or 400 mg/kg of WR-2721 immediately before testing. Horizontal and vertical activity were measured using a Digiscan automated animal activity monitor. The latency to onset and duration of action of each dose of the radioprotector were recorded. For both behavioral measures, a significant reduction was observed in activity at doses of 200 and 400 mg/kg. A dose of 200 mg/kg had a 12- to 14-min latency to onset and significantly reduced behavioral activity for 3 hr. Mice injected with 400 mg/kg exhibited locomotor deficits within 8-10 min and were affected for up to 9 hr. The ED50 for horizontal and vertical activities at 1 hr postinjection were determined to be 271 and 105 mg/kg, respectively. The results demonstrate that significant reductions in locomotor activity are exhibited at doses of 200 mg/kg or more and that vertical activity was more sensitive to the disruptive effects of WR-2721 than was horizontal activity

Future Circular Colliders

CERN Document Server

AUTHOR|(CDS)2108454; Zimmermann, Frank

2016-01-01

In response to a request from the 2013 Update of the European Strategy for Particle Physics, the global Future Circular Collider (FCC) study is preparing the foundation for a next-generation large-scale accelerator infrastructure in the heart of Europe. The FCC study focuses on the design of a 100-TeV hadron collider (FCC-hh), to be accommodated in a new ∼100 km tunnel near Geneva. It also includes the design of a high-luminosity electron-positron collider (FCC-ee), which could be installed in the same tunnel as a potential intermediate step, and a lepton-hadron collider option (FCC-he). The scope of the FCC study comprises accelerators, technology, infrastructure, detector, physics, concepts for worldwide data services, international governance models, and implementation scenarios. Among the FCC core technologies figure 16-T dipole magnets, based on Nb$_{3}$Sn superconductor, for the FCC-hh hadron collider, and a highly efficient superconducting radiofrequency system for the FCC-ee lepton collider. The int...

Future Circular Colliders

CERN Document Server

AUTHOR|(CDS)2108454; Zimmermann, Frank

2016-01-01

In response to a request from the 2013 Update of the European Strategy for Particle Physics, the global Future Circular Collider (FCC) study is preparing the foundation for a next-generation large-scale accelerator infrastructure in the heart of Europe. The FCC study focuses on the design of a 100-TeV hadron collider (FCC-hh), to be accommodated in a new ∼100 km tunnel near Geneva. It also includes the design of a high-luminosity electron-positron collider (FCC-ee), which could be installed in the same tunnel as a potential intermediate step, and a lepton-hadron collider option (FCC-he). The scope of the FCC study comprises accelerators, technology, infrastructure, detectors, physics, concepts for worldwide data services, international governance models, and implementation scenarios. Among the FCC core technologies figure 16-T dipole magnets, based on Nb$_{3}$Sn superconductor, for the FCC-hh hadron collider, and a highly efficient superconducting radiofrequency system for the FCC-ee lepton collider. The in...

Berkeley mini-collider

International Nuclear Information System (INIS)

Schroeder, L.S.

1984-06-01

The Berkeley Mini-Collider, a heavy-ion collider being planned to provide uranium-uranium collisions at T/sub cm/ less than or equal to 4 GeV/nucleon, is described. The central physics to be studied at these energies and our early ideas for a collider detector are presented

Detached dust shell around Wolf-Rayet star WR60-6 in the young stellar cluster VVV CL036

Energy Technology Data Exchange (ETDEWEB)

Borissova, J.; Amigo, P.; Kurtev, R. [Departamento de Física y Astronomía, Universidad de Valparaíso, Av. Gran Bretaña 1111, Playa Ancha, Casilla 5030 (Chile); Kumar, M. S. N. [Centro de Astrofísica da Universidade do Porto, Rua das Estrelas, 4150-762 Porto (Portugal); Chené, A.-N. [Gemini Observatory, Northern Operations Center, 670 North A' ohoku Place Hilo, HI 96720 (United States); Minniti, D., E-mail: jura.borissova@uv.cl [Pontificia Universidad Católica de Chile, Facultad de Física, Departamento de Astronomía y Astrofísica, Av. Vicuña Mackenna 4860, 782-0436 Macul, Santiago (Chile)

2014-01-01

The discovery of a detached dust shell around the Wolf-Rayet (WR) star WR60-6 in the young stellar cluster VVV CL036 is reported. This shell is uncovered through the Spitzer-MIPS 24 μm image, where it appears brightest, and it is invisible at shorter wavelengths. Using new APEX observations and other data available from the literature, we have estimated some of the shell parameters: the inner and outer radii of 0.15 and 0.90 pc, respectively; the overall systemic velocity of the molecular {sup 12}CO(3 → 2) emission of –45.7 ± 2.3 km s{sup –1}; an expansion velocity of the gas of 16.3 ± 1 km s{sup –1}; the dust temperature and opacity of 122 ± 12 K and 1.04, respectively; and an age of 2.8 × 10{sup 4} yr. The WR star displays some cyclic variability. The mass computed for the WR60-6 nebula indicates that the material was probably ejected during its previous stages of evolution. In addition, we have identified a bright spot very close to the shell, which can be associated with the Midcourse Space Experiment source G312.13+00.20.

[Clinical case of the month. Mild hemolytic disease of the newborn due to an anti-Wr(a) antibody].

Science.gov (United States)

Keutgens, A; Monfort, M; Wagemans, D; Van Cauwenberge, J-R; Gérard, C

2012-01-01

A Caucasian woman, with a A+ CCD.ee K neg erythrocyte phenotype and no history of blood transfusion, delivered a first child who developed mild anemia. The direct antiglobulin test performed on the newborn red blood cells belonging to the A+ CCD.ee K neg group, was strongly positive for IgG. During the pregnancy and after the delivery, the woman had a negative irregular antibody screening test, using standard red blood cells. However, at birth, using a collection of thawed red blood cells with rare phenotypes (private antigens), the lab showed an antibody anti-Wr(a) in the maternal serum. The activity of the maternal antibody, with a titer of 16, was completely inhibited by dithiothreitol, indicating the nature IgM of the circulating antibody. The presence of the antigen Wr(a) on the surface of the newborn and its biological father red blood cells was confirmed. The concentration of IgG anti-Wr(a) on baby erythrocytes was demonstrated by the presence of the antibody anti-Wr(a) in the eluate. This case illustrates the difficulties to detect antibodies against private antigens on baby erythrocytes, responsible of hemolytic diseases of newborn. Indeed, standard red blood cell panels used for irregular antibodies screening test do not express generally those private antigens.

Prospects for colliders and collider physics to the 1 PeV energy scale

Science.gov (United States)

King, Bruce J.

2000-08-01

A review is given of the prospects for future colliders and collider physics at the energy frontier. A proof-of-plausibility scenario is presented for maximizing our progress in elementary particle physics by extending the energy reach of hadron and lepton colliders as quickly and economically as might be technically and financially feasible. The scenario comprises 5 colliders beyond the LHC—one each of e+e- and hadron colliders and three μ+μ- colliders — and is able to hold to the historical rate of progress in the log-energy reach of hadron and lepton colliders, reaching the 1 PeV constituent mass scale by the early 2040's. The technical and fiscal requirements for the feasibility of the scenario are assessed and relevant long-term R&D projects are identified. Considerations of both cost and logistics seem to strongly favor housing most or all of the colliders in the scenario in a new world high energy physics laboratory.

Ion Colliders

CERN Document Server

Fischer, W

2014-01-01

High-energy ion colliders are large research tools in nuclear physics to study the Quark-Gluon-Plasma (QGP). The range of collision energy and high luminosity are important design and operational considerations. The experiments also expect flexibility with frequent changes in the collision energy, detector fields, and ion species. Ion species range from protons, including polarized protons in RHIC, to heavy nuclei like gold, lead and uranium. Asymmetric collision combinations (e.g. protons against heavy ions) are also essential. For the creation, acceleration, and storage of bright intense ion beams, limits are set by space charge, charge change, and intrabeam scattering effects, as well as beam losses due to a variety of other phenomena. Currently, there are two operating ion colliders, the Relativistic Heavy Ion Collider (RHIC) at BNL, and the Large Hadron Collider (LHC) at CERN.

Asymmetric collider

International Nuclear Information System (INIS)

Bharadwaj, V.; Colestock, P.; Goderre, G.; Johnson, D.; Martin, P.; Holt, J.; Kaplan, D.

1993-01-01

The study of CP violation in beauty decay is one of the key challenges facing high energy physics. Much work has not yielded a definitive answer how this study might best be performed. However, one clear conclusion is that new accelerator facilities are needed. Proposals include experiments at asymmetric electron-positron colliders and in fixed-target and collider modes at LHC and SSC. Fixed-target and collider experiments at existing accelerators, while they might succeed in a first observation of the effect, will not be adequate to study it thoroughly. Giomataris has emphasized the potential of a new approach to the study of beauty CP violation: the asymmetric proton collider. Such a collider might be realized by the construction of a small storage ring intersecting an existing or soon-to-exist large synchrotron, or by arranging collisions between a large synchrotron and its injector. An experiment at such a collider can combine the advantages of fixed-target-like spectrometer geometry, facilitating triggering, particle identification and the instrumentation of a large acceptance, while the increased √s can provide a factor > 100 increase in beauty-production cross section compared to Tevatron or HERA fixed-target. Beams crossing at a non-zero angle can provide a small interaction region, permitting a first-level decay-vertex trigger to be implemented. To achieve large √s with a large Lorentz boost and high luminosity, the most favorable venue is the high-energy booster (HEB) at the SSC Laboratory, though the CERN SPS and Fermilab Tevatron are also worth considering

Protection against the clastogenic effect of CIS-PLATINUM by WR-2721, ATP and Vitamin C

International Nuclear Information System (INIS)

Rupova, I.; Yagova, A.

1993-01-01

The mutagenic effect of antineoplastic drug Cis-Platinum has been assessed by the frequency of micronuclei in polychromatic erythrocytes (PE) in the mouse bone marrow at time intervals of 24, 48 and 73 h. The maximal clastogenic effect of 2 mg/kg of Cis-Platinum has been found at 24 h interval after treatment (3.6%). The protection against mutagenic activity of Cis-Platinum has been studied by pretreatment of the mice with the thiophosphate compound WR-2721, adenosine triphosphate (ATP) and Vitamin C alone or in combinations at the time of maximal response. The radioprotector WR-2721 exerts a high anti-mutagenic activity when applied prior to Cis-Platinum (2.2%; p 0.05). (author)

Survival of bone marrow-engrafted mice subsequent to protection from lethal radiation by WR 2721

International Nuclear Information System (INIS)

Kinnamon, K.E.; Ketterling, L.L.; Ledney, G.D.; Lorenz, G.B.; Mioduszewski, R.J.; Stampfli, H.F.

1980-01-01

For the first time data are presented for animals treated with bone marrow cells after lethal radiation exposure while protected with WR 2721 (the single radioprotective chemical compound with the highest known dose reduction factor). The LD 50 30 (lethal dose to 50% in 30 days) for mice exposed to whole-body 60 Co radiation was elevated from 824 +- 8 rad in unprotected and untreated mice to (a) 1181 +- 33 rad in animals which received syngeneic bone marrow cells after exposure; (b) 1342 +- 27 rad in animals which received WR 2721 before radiation exposure; and (c) 1608 +- 33 rad in animals receiving both the radioprotective agent before exposure and bone marrow engraftment after exposure

Inhibition of topoisomerase II activity in repair-proficient CHO K1 cells by 2-[(aminopropyl)amino]ethanethiol (WR-1065)

International Nuclear Information System (INIS)

Grdina, D.J.; Constantinou, A.; Shigematsu, N.

1992-09-01

The aminothiol 2-[(aminopropyl)amino]ethanethiol (WR-1065) is the active thiol of the clinically studied radioprotective agent S-2-(3-aminopropylamino) ethylphosphorothioic acid (WR-2721). WR-1065 is an effective radiation protector under in vitro conditions when it is administered 30 min prior to radiation exposure at a concentration of 4 mM to repair-proficient Chinese hamster ovary Kl cells (i.e., a dose modification factor of 1.4). In contrast, the DNA double-strand break, repair-deficient Chinese hamster ovary xrs-5 cell line is not protected under these conditions (i.e., a dose modification factor of 1.0). Topoisomerase (topo) I and II activities and protein contents were measured in both Kl and xrs-5 cell lines and were found to be similar in magnitude. Neither exposure to radiation, to WR-1065, or to both affected these variables in xrs-5 cells. WR 1065 was effective, however, in reducing topo 11 activity by a factor of 2 in the repair-proficient Kl cell line. Topo II protein content, however, was not affected by these exposure conditions. One of several mechanisms of radiation protection attributed to aminothiol compounds has been their ability to affect enzymatic reactions involved in DNA synthesis, repair, and cell cycle progression. These results demonstrate a modifying effect by 2-[(aminopropyl)amino]ethanethiol on a specific nuclear enzyme (i.e., type H topoisomerase), which is involved in DNA synthesis. These results also suggest that differences do exist between the topo 11 enzymes isolated from the parent repair-proficient Kl and the DNA double-strand break, repair-deficient xrs-5 mutant cell lines

Inhibition of topoisomerase II activity in repair-proficient CHO K1 cells by 2-[(aminopropyl)amino]ethanethiol (WR-1065)

Energy Technology Data Exchange (ETDEWEB)

Grdina, D.J.; Constantinou, A.; Shigematsu, N.

1992-09-01

The aminothiol 2-[(aminopropyl)amino]ethanethiol (WR-1065) is the active thiol of the clinically studied radioprotective agent S-2-(3-aminopropylamino) ethylphosphorothioic acid (WR-2721). WR-1065 is an effective radiation protector under in vitro conditions when it is administered 30 min prior to radiation exposure at a concentration of 4 mM to repair-proficient Chinese hamster ovary Kl cells (i.e., a dose modification factor of 1.4). In contrast, the DNA double-strand break, repair-deficient Chinese hamster ovary xrs-5 cell line is not protected under these conditions (i.e., a dose modification factor of 1.0). Topoisomerase (topo) I and II activities and protein contents were measured in both Kl and xrs-5 cell lines and were found to be similar in magnitude. Neither exposure to radiation, to WR-1065, or to both affected these variables in xrs-5 cells. WR 1065 was effective, however, in reducing topo 11 activity by a factor of 2 in the repair-proficient Kl cell line. Topo II protein content, however, was not affected by these exposure conditions. One of several mechanisms of radiation protection attributed to aminothiol compounds has been their ability to affect enzymatic reactions involved in DNA synthesis, repair, and cell cycle progression. These results demonstrate a modifying effect by 2-[(aminopropyl)amino]ethanethiol on a specific nuclear enzyme (i.e., type H topoisomerase), which is involved in DNA synthesis. These results also suggest that differences do exist between the topo 11 enzymes isolated from the parent repair-proficient Kl and the DNA double-strand break, repair-deficient xrs-5 mutant cell lines.

Protein binding of N-2-mercaptoethyl-1,3-diaminopropane via mixed disulfide formation after oral administration of WR 2721

Energy Technology Data Exchange (ETDEWEB)

Tabachnik, N.F.; Blackburn, P.; Peterson, C.M.; Cerami, A.

1982-02-01

Earlier studies have shown that WR 2721 (H2N-(CH2)3-NH(CH2)2SPO3H2) is converted to its free thiol form, N-2-mercaptoethyl-1,3-diaminopropane (MDP), at the acidic pH of the stomach. MDP is a radioprotective compound and a mucolytic agent capable of decreasing sputum viscosity in the lungs of patients with cystic fibrosis. Conversion of WR 2721 and MDP to the corresponding sulfonic acid (MDP-SO3H) permits quantitative determination of these compounds in physiological fluids by use of an automatic amino acid analyzer. After oral administration of WR 2721 to human patients and rabbits it is converted to MDP and the free thiol form of the drug associates with plasma proteins by mixed disulfide linkage. The plasma proteins serve as a depot and reservoir of MDP for potential exchange at the tissues. When incubated with whole sputum or with purified mucin solutions in vitro, MDP decreased the viscosity of these solutions by reduction of the accessible disulfide bonds of the mucin molecule and was subsequently found in mixed disulfide association with the mucin molecule. The association of MDP with proteins via mixed disulfide linkage has important implications for the development of optimal dose regimens for administration of WR 2721 to patients.

Protein binding of N-2-mercaptoethyl-1,3-diaminopropane via mixed disulfide formation after oral administration of WR 2721

International Nuclear Information System (INIS)

Tabachnik, N.F.; Blackburn, P.; Peterson, C.M.; Cerami, A.

1982-01-01

Earlier studies have shown that WR 2721 [H2N-(CH2)3-NH(CH2)2SPO3H2] is converted to its free thiol form, N-2-mercaptoethyl-1,3-diaminopropane (MDP), at the acidic pH of the stomach. MDP is a radioprotective compound and a mucolytic agent capable of decreasing sputum viscosity in the lungs of patients with cystic fibrosis. Conversion of WR 2721 and MDP to the corresponding sulfonic acid (MDP-SO3H) permits quantitative determination of these compounds in physiological fluids by use of an automatic amino acid analyzer. After oral administration of WR 2721 to human patients and rabbits it is converted to MDP and the free thiol form of the drug associates with plasma proteins by mixed disulfide linkage. The plasma proteins serve as a depot and reservoir of MDP for potential exchange at the tissues. When incubated with whole sputum or with purified mucin solutions in vitro, MDP decreased the viscosity of these solutions by reduction of the accessible disulfide bonds of the mucin molecule and was subsequently found in mixed disulfide association with the mucin molecule. The association of MDP with proteins via mixed disulfide linkage has important implications for the development of optimal dose regimens for administration of WR 2721 to patients

76 FR 10899 - Decision To Evaluate a Petition To Designate a Class of Employees From the W.R. Grace and Company...

Science.gov (United States)

2011-02-28

... Employees From the W.R. Grace and Company in Curtis, MD, To Be Included in the Special Exposure Cohort... evaluate a petition to designate a class of employees from the W.R. Grace and Company in Curtis, Maryland... Compensation Program Act of 2000. The initial proposed definition for the class being evaluated, subject to...

2-[(aminopropyl)amino]ethanethiol (WR1065) is anti-neoplastic and anti-mutagenic when given during 60Coγ-ray irradiation

International Nuclear Information System (INIS)

Hill, C.K.; Nagy, B.; Peraino, C.; Grdina, D.

1986-01-01

The effect of 2[(aminopropyl)amino]ethanethiol (WR1065) has been studied on the induction of neoplastic transformation using 10T1/2 cells and on mutation of the hypoxanthine guanine phosphoribosyl transferase (HGPRT) locus using Chinese hamster V79 cells. The first observations that treatment of 10T1/2 cells with 1 mM WR1065 for a total of 35 min during irradiation with 60 C γ-rays significantly reduces the incidence of neoplastic transformation while having no effect on cell viability are reported. In a similar experiment with V79 cells in which 4mM WR1065 was used, a significant reduction in mutation frequency at the HGPRT locus and significant protection against cell killing was found. These results suggest that WR1965 acts to modulate both acute damage and sub-lethal processes that lead to mutation and neoplastic transformation. Beyond the purely mechanistic approach of these studies, the potential application of these agents to minimizing the long-term neoplastic effects of radiation or chemotherapeutic agents currently in use for treating potentially curable cancer patients should be further investigated. (author)

Birds and wind power. Technical report 1977-1982; Faglar och vindkraft. Teknisk rapport 1977-1982

Energy Technology Data Exchange (ETDEWEB)

Karlsson, Johnny

1983-02-15

The impact of wind power plants on birds has been studied. The risk of migrating birds colliding with high buildings has been investigated. Different hazards and accidents are described and reported in 12 appendices. Preliminary data from the sites of wind power plants are presented.

Protection against radiation-induced mutations at the hprt locus by spermine and N,N double-prime-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278)

International Nuclear Information System (INIS)

Grdina, D.J.; Schwartz, J.L.; Shigematsu, N.

1993-06-01

The polyamine spermine and the disulfide NN double-prime-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278) are structurally similar agents capable of binding to DNA. WR-33278 is the disulfide moiety of the clinically studied radioprotective agent (WR-2721). Because of their structural similarities, it was of interest to characterize and compare their radioprotective properties using the endpoints of cell survival and mutation induction at the hypoxanthine-guanine phosphoribosyl transferase (hprt) locus in Chinese hamster AA8 cells. In order to facilitate both the uptake of VM-33278 into cells and the direct comparison between the protective properties of WR-33278 and spermine, these agents were electroporated into cells. Electroporation alone reduced cell survival to 75% but had no effect on hprt mutation frequency. The electroporation of either spermine or WR-33278 at concentrations greater than 0.01 mM was extremely toxic. The exposure of cells to both electroporation and irradiation gave rise to enhanced cell killing and mutation induction. Cell survival values at a radiation dose of 750 cGy were enhanced by factors of 1.3 and 1.8 following electroporation of 0.01 mM of spermine and WR-33278, respectively, 30 min prior to irradiation. Neither agent was protective at a concentration of 0.001 mM. Protection against radiation-induced hprt mutations was observed for both spermine and WR-33278 under all experimental conditions tested

Chandra Observations of the Eclipsing Wolf-Rayet Binary CQ CepOver a Full Orbital Cycle

Science.gov (United States)

Skinner, Steve L.; Guedel, Manuel; Schmutz, Werner; Zhekov, Svetozar

2018-06-01

We present results of Chandra X-ray observations and simultaneous optical light curves of the short-period (1.64 d) eclipsing WN6+O9 binary system CQ Cep obtained in 2013 and 2017 covering a full binary orbit. Our primary objective was to compare the observed X-ray properties with colliding wind shock theory, which predicts that the hottest shock plasma (T > 20 MK) will form on or near the line-of-centers between the stars. Thus, X-ray variability is expected during eclipses when the hottest plasma is occulted. The X-ray spectrum is strikingly similar to apparently single WN6 stars such as WR 134 and spectral lines reveal plasma over a broad range of temperatures T ~ 4 - 40 MK. Both primary and secondary optical eclipses were clearly detected and provide an accurate orbital period determination (P = 1.6412 d). The X-ray emission remained remarkably steady throughout the orbit and statistical tests give a low probability of variability. The lack of significant X-ray variabililty during eclipses indicates that the X-ray emission is not confined along the line-of-centers but is extended on larger spatial scales, contrary to colliding wind predictions.

Linear colliders - prospects 1985

International Nuclear Information System (INIS)

Rees, J.

1985-06-01

We discuss the scaling laws of linear colliders and their consequences for accelerator design. We then report on the SLAC Linear Collider project and comment on experience gained on that project and its application to future colliders. 9 refs., 2 figs

Impact of wind turbines on birds

International Nuclear Information System (INIS)

Clausager, I.; Nohr, H.

1996-01-01

The paper is a review of the present knowledge on impacts of wind turbines on birds, requested by the Danish Ministry of the Environment and Energy. The main conclusions of the review are, that in nearly all the studies so far the numbers of birds recorded colliding with wind turbines have been limited. Some studies indicate that stationary (breeding) birds inside the wind turbine area in the short run habituate to wind turbines, especially the noise and visual impacts, and that the risk for collision becomes low. However, some of the few more long term studies indicate that a negative impact may occur in later generations of breeding birds. In some studies a disturbance effect on bird species, which temporarily stay inside a wind turbine area in order to forage or rest, is observed. The degree of impact is species-specific. An effect is typically recorded inside a zone of up to 250-800 m, with geese and waders as the most sensitive groups of birds. (author)

Relationship between velocity gradients and magnetic turbulence in the solar wind

International Nuclear Information System (INIS)

Garrett, H.B.

1974-01-01

The correlations among the time derivative of the solar-wind velocity, the magnitude of the interplanetary magnetic field (IMF), and the IMF turbulence level are examined to test the idea that interaction between two colliding solar-wind streams can generate turbulence in the solar wind and the IMF. Data obtained by Explorer 33 on the solar wind and IMF are described, and the analysis techniques are outlined. The results indicate that the IMF turbulence level, as measured by the variance, is correlated with the existence of positive velocity gradients in the solar wind. It is noted that while the variance is an increasing function of the field magnitude, it is also independently correlated with the solar-wind velocity gradient

Effect of an aminothiol (WR-1065) on radiation-induced mutagenesis and cytotoxicity in two repair-deficient mammalian cell lines

International Nuclear Information System (INIS)

Grdina, D.J.; Nagy, B.; Meechan, P.J.

1991-01-01

WR-2721 and its free thiol WR-1065 have been found to effectively protect against radiation- and/or chemotherapy-induced mutagenesis, transformation and carcinogenesis. With respect to the antimutagenic effect, WR-1065 significantly reduced the frequency of HGPRT mutants even when it was administered up to three hours following exposure of cells to radiation. The mechanisms of action most often attributed to these agents include their ability to scavenge free radicals, enter into chemical repair processes through the donation of hydrogen atoms, and induce intracellular hypoxia by means of auto-oxidative processes. Although evidence exists for each of these processes, none is sufficiently satisfactory to account for the post-irradiation protection of WR-1065 against mutation induction in mammalian cells. The most elegant work describing the role of aminothiols on cellular enzymatic repair processes has focused on well-characterized repair-proficient and -deficient bacterial and yeast cell systems. Protection against radiation-induced cytotoxicity by the aminothiol cysteamine was absent in E. coli cell lines that were characterized as having genetically defective repair systems. Until recently, such studies could not be effectively performed with mammalian cells. However, with the isolation and characterization of rodent cell lines deficient in their ability to repair DNA damage, it is now possible to investigate the role of cell-mediated repair systems on aminothiol radioprotection. Specifically, the authors have investigated the effects of WR-1065 on radiation-induced mutagenesis and cytotoxicity in cell lines EM9 and xrs-5, which are defective in DNA single-strand break (SSB) and double-strand break (DSB) rejoining, respectively. Corresponding parental repair-proficient cell lines, AA8 and K1, were also studied for comparative purposes. 26 refs., 5 figs., 2 tabs

Collider workshop

International Nuclear Information System (INIS)

Anon.

1982-01-01

The promise of initial results after the start of operations at CERN's SPS proton-antiproton collider and the prospects for high energy hadron collisions at Fermilab (Tevatron) and Brookhaven (ISABELLE) provided a timely impetus for the recent Topical Workshop on Forward Collider Physics', held at Madison, Wisconsin, from 10-12 December. It became the second such workshop to be held, the first having been in 1979 at the College de France, Paris. The 100 or so participants had the chance to hear preliminary results from the UA1, UA4 and UA5 experiments at the CERN SPS collider, together with other new data, including that from proton-antiproton runs at the CERN Intersecting Storage Rings

Towards a Muon Collider

International Nuclear Information System (INIS)

Eichten, E.

2011-01-01

A multi TeV Muon Collider is required for the full coverage of Terascale physics. The physics potential for a Muon Collider at ∼3 TeV and integrated luminosity of 1 ab -1 is outstanding. Particularly strong cases can be made if the new physics is SUSY or new strong dynamics. Furthermore, a staged Muon Collider can provide a Neutrino Factory to fully disentangle neutrino physics. If a narrow s-channel resonance state exists in the multi-TeV region, the physics program at a Muon Collider could begin with less than 10 31 cm -2 s -1 luminosity. Detailed studies of the physics case for a 1.5-4 TeV Muon Collider are just beginning. The goals of such studies are to: (1) identify benchmark physics processes; (2) study the physics dependence on beam parameters; (3) estimate detector backgrounds; and (4) compare the physics potential of a Muon Collider with those of the ILC, CLIC and upgrades to the LHC.

The environment of the wind-wind collision region of η Carinae

Science.gov (United States)

Panagiotou, C.; Walter, R.

2018-02-01

Context. η Carinae is a colliding wind binary hosting two of the most massive stars and featuring the strongest wind collision mechanical luminosity. The wind collision region of this system is detected in X-rays and γ-rays and offers a unique laboratory for the study of particle acceleration and wind magneto-hydrodynamics. Aim. Our main goal is to use X-ray observations of η Carinae around periastron to constrain the wind collision zone geometry and understand the reasons for its variability. Methods: We analysed 10 Nuclear Spectroscopic Telescope Array (NuSTAR) observations, which were obtained around the 2014 periastron. The NuSTAR array monitored the source from 3 to 30 keV, which allowed us to grasp the continuum and absorption parameters with very good accuracy. We were able to identify several physical components and probe their variability. Results: The X-ray flux varied in a similar way as observed during previous periastrons and largely as expected if generated in the wind collision region. The flux detected within 10 days of periastron is lower than expected, suggesting a partial disruption of the central region of the wind collision zone. The Fe Kα line is likely broadened by the electrons heated along the complex shock fronts. The variability of its equivalent width indicates that the fluorescence region has a complex geometry and that the source obscuration varies quickly with the line of sight.

LEW.1WR1 RATS DEVELOP AUTOIMMUNE DIABETES SPONTANEOUSLY AND IN RESPONSE TO ENVIRONMENTAL PERTURBATION

Science.gov (United States)

Mordes, John P.; Leif, Jean H.; Woda, Bruce A.; Flanagan, Joan F.; Greiner, Dale L.; Kislauskis, Edward H.; Tirabassi, Rebecca S.

2005-01-01

We describe a new rat model of autoimmune diabetes that arose in a major histocompatibility complex (MHC) congenic LEW rat. Spontaneous diabetes in LEW.1WR1 rats (RT1u/u/a) occurs with a cumulative frequency of ∼2% at a median age of 59 days. The disease is characterized by hyperglycemia, glycosuria, ketonuria and polyuria. Both sexes are affected, and islets of acutely diabetic rats are devoid of beta cells whereas alpha and delta cell populations are spared. The peripheral lymphoid phenotype is normal, including the fraction of ART2+ regulatory T cells (Tregs). We tested the hypothesis that the expression of diabetes would be increased by immunological perturbation of innate or adaptive immunity. Treatment of young rats with depleting anti-ART2.1 mAb increased the frequency of diabetes to 50%. Treatment with the toll-like receptor 3 (TLR3) ligand polyinosinic:polycytidylic acid increased the frequency of diabetes to 100%. All diabetic rats exhibited end-stage islets. The LEW.1WR1 rat is also susceptible to collagen-induced arthritis but is free of spontaneous thyroiditis. The LEW.1WR1 rat provides a new model for studying autoimmune diabetes and arthritis in an animal with a genetic predisposition to both disorders that can be amplified by environmental perturbation. PMID:16123363

Draft genome sequence of the intestinal parasite Blastocystis subtype 4-isolate WR1

NARCIS (Netherlands)

Wawrzyniak, Ivan; Courtine, Damien; Osman, Marwan; Hubans-Pierlot, Christine; Cian, Amandine; Nourrisson, Céline; Chabe, Magali; Poirier, Philippe; Bart, Aldert; Polonais, Valérie; Delgado-Viscogliosi, Pilar; El Alaoui, Hicham; Belkorchia, Abdel; van Gool, Tom; Tan, Kevin S. W.; Ferreira, Stéphanie; Viscogliosi, Eric; Delbac, Frédéric

2015-01-01

(ST1-ST17) described to date. Only the whole genome of a human ST7 isolate was previously sequenced. Here we report the draft genome sequence of Blastocystis ST4-WR1 isolated from a laboratory rodent at Singapore. (C) 2015 The Authors. Published by Elsevier Inc

Towards future circular colliders

Science.gov (United States)

Benedikt, Michael; Zimmermann, Frank

2016-09-01

The Large Hadron Collider (LHC) at the European Organization for Nuclear Research (CERN) presently provides proton-proton collisions at a center-of-mass (c.m.) energy of 13 TeV. The LHC design was started more than 30 years ago, and its physics program will extend through the second half of the 2030's. The global Future Circular Collider (FCC) study is now preparing for a post-LHC project. The FCC study focuses on the design of a 100-TeV hadron collider (FCC-hh) in a new ˜100 km tunnel. It also includes the design of a high-luminosity electron-positron collider (FCCee) as a potential intermediate step, and a lepton-hadron collider option (FCC-he). The scope of the FCC study comprises accelerators, technology, infrastructure, detectors, physics, concepts for worldwide data services, international governance models, and implementation scenarios. Among the FCC core technologies figure 16-T dipole magnets, based on Nb3 S n superconductor, for the FCC-hh hadron collider, and a highly-efficient superconducting radiofrequency system for the FCC-ee lepton collider. Following the FCC concept, the Institute of High Energy Physics (IHEP) in Beijing has initiated a parallel design study for an e + e - Higgs factory in China (CEPC), which is to be succeeded by a high-energy hadron collider (SPPC). At present a tunnel circumference of 54 km and a hadron collider c.m. energy of about 70 TeV are being considered. After a brief look at the LHC, this article reports the motivation and the present status of the FCC study, some of the primary design challenges and R&D subjects, as well as the emerging global collaboration.

Very high energy colliders

International Nuclear Information System (INIS)

Richter, B.

1986-03-01

The luminosity and energy requirements are considered for both proton colliders and electron-positron colliders. Some of the basic design equations for high energy linear electron colliders are summarized, as well as design constraints. A few examples are given of parameters for very high energy machines. 4 refs., 6 figs

ColliderBit. A GAMBIT module for the calculation of high-energy collider observables and likelihoods

Energy Technology Data Exchange (ETDEWEB)

Balazs, Csaba [Monash University, School of Physics and Astronomy, Melbourne, VIC (Australia); Australian Research Council Centre of Excellence for Particle Physics at the Tera-scale (Australia); Buckley, Andy [University of Glasgow, SUPA, School of Physics and Astronomy, Glasgow (United Kingdom); Dal, Lars A.; Krislock, Abram; Raklev, Are [University of Oslo, Department of Physics, Oslo (Norway); Farmer, Ben [AlbaNova University Centre, Oskar Klein Centre for Cosmoparticle Physics, Stockholm (Sweden); Jackson, Paul; Murnane, Daniel; White, Martin [Australian Research Council Centre of Excellence for Particle Physics at the Tera-scale (Australia); University of Adelaide, Department of Physics, Adelaide, SA (Australia); Kvellestad, Anders [NORDITA, Stockholm (Sweden); Putze, Antje [Universite de Savoie, LAPTh, Annecy-le-Vieux (France); Rogan, Christopher [Harvard University, Department of Physics, Cambridge, MA (United States); Saavedra, Aldo [Australian Research Council Centre of Excellence for Particle Physics at the Tera-scale (Australia); The University of Sydney, Faculty of Engineering and Information Technologies, Centre for Translational Data Science, School of Physics, Sydney, NSW (Australia); Scott, Pat [Imperial College London, Blackett Laboratory, Department of Physics, London (United Kingdom); Weniger, Christoph [University of Amsterdam, GRAPPA, Institute of Physics, Amsterdam (Netherlands); Collaboration: The GAMBIT Scanner Workgroup

2017-11-15

We describe ColliderBit, a new code for the calculation of high energy collider observables in theories of physics beyond the Standard Model (BSM). ColliderBit features a generic interface to BSM models, a unique parallelised Monte Carlo event generation scheme suitable for large-scale supercomputer applications, and a number of LHC analyses, covering a reasonable range of the BSM signatures currently sought by ATLAS and CMS. ColliderBit also calculates likelihoods for Higgs sector observables, and LEP searches for BSM particles. These features are provided by a combination of new code unique toColliderBit, and interfaces to existing state-of-the-art public codes. ColliderBit is both an important part of the GAMBIT framework for BSM inference, and a standalone tool for efficiently applying collider constraints to theories of new physics. (orig.)

Proton-antiproton collider physics

CERN Document Server

Altarelli, Guido

1989-01-01

This volume reviews the physics studied at the CERN proton-antiproton collider during its first phase of operation, from the first physics run in 1981 to the last one at the end of 1985. The volume consists of a series of review articles written by physicists who are actively involved with the collider research program. The first article describes the proton-antiproton collider facility itself, including the antiproton source and its principle of operation based on stochastic cooling. The subsequent six articles deal with the various physics subjects studied at the collider. Each article descr

Radioprotective action of WR-1065 on radiation-induced DNA strand breaks in cultured Chinese hamster ovary cells

International Nuclear Information System (INIS)

Murray, D.; VanAnkeren, S.C.; Milas, L.; Meyn, R.E.

1988-01-01

We have examined the radioprotective effect of WR-1065 on cultured Chinese hamster ovary cells. The effects of the drug on the induction and rejoining of gamma-ray-induced DNA single-strand breaks (SSBs) and double-strand breaks (DSBs) were measured using alkaline (pH 12.1) and neutral (pH 7.0) elution, respectively. Molecular protection factors (PFs) calculated from these data allowed us to determine whether the degree of modification of strand breakage accurately predicted the PFs measured using the biological end point of cell survival. The drug did protect against the induction of both SSBs and DSBs, although to an extent that did not appear to fully account for the degree of radioprotection in terms of cell killing measured under identical conditions. It is therefore unlikely that radioprotection by WR-1065 occurs simply as a consequence of a general lowering of all types of gamma-ray-induced DNA lesions, and it is possible that the drug could differentially protect against the induction of subsets of these DNA lesions. The rate of SSB rejoining was retarded following preirradiation treatment of cells with WR-1065, but there was no effect on DSB rejoining. Postirradiation treatment with WR-1065 also appeared to retard SSB rejoining but without an accompanying effect on either DSB rejoining or cell survival; however, this effect was largely reversed by the addition of catalase and was, therefore, probably a result of H 2 O 2 generated by autoxidation of the drug. Based on these observations, it would appear that the molecular actions of aminothiol radioprotective compounds that lead to reduced cell killing are much more complex than previously thought

Collider Physics

OpenAIRE

Zeppenfeld, D.

1999-01-01

These lectures are intended as a pedagogical introduction to physics at $e^+e^-$ and hadron colliders. A selection of processes is used to illustrate the strengths and capabilities of the different machines. The discussion includes $W$ pair production and chargino searches at $e^+e^-$ colliders, Drell-Yan events and the top quark search at the Tevatron, and Higgs searches at the LHC.

Towards Future Circular Colliders

CERN Document Server

AUTHOR|(CDS)2108454; Zimmermann, Frank

2016-01-01

The Large Hadron Collider (LHC) at CERN presently provides proton-proton collisions at a centre-of-mass (c.m.) energy of 13 TeV. The LHC design was started more than 30 years ago, and its physics programme will extend through the second half of the 2030’s. The global Future Circular Collider (FCC) study is now preparing for a post-LHC project. The FCC study focuses on the design of a 100-TeV hadron collider (FCC-hh) in a new ∼100 km tunnel. It also includes the design of a high-luminosity electron-positron collider (FCC-ee) as a potential intermediate step, and a lepton-hadron collider option (FCC-he). The scope of the FCC study comprises accelerators, technology, infrastructure, detectors, physics, concepts for worldwide data services, international governance models, and implementation scenarios. Among the FCC core technologies figure 16-T dipole magnets, based on $Nb_3Sn$ superconductor, for the FCC-hh hadron collider, and a highly efficient superconducting radiofrequency system for the FCC-ee lepton c...

Photon-photon colliders

International Nuclear Information System (INIS)

Sessler, A.M.

1995-04-01

Since the seminal work by Ginsburg, et at., the subject of giving the Next Linear Collider photon-photon capability, as well as electron-positron capability, has drawn much attention. A 1990 article by V.I. Teinov describes the situation at that time. In March 1994, the first workshop on this subject was held. This report briefly reviews the physics that can be achieved through the photon-photon channel and then focuses on the means of achieving such a collider. Also reviewed is the spectrum of backscattered Compton photons -- the best way of obtaining photons. We emphasize the spectrum actually obtained in a collider with both polarized electrons and photons (peaked at high energy and very different from a Compton spectrum). Luminosity is estimated for the presently considered colliders, and interaction and conversion-point geometries are described. Also specified are laser requirements (such as wavelength, peak power, and average power) and the lasers that might be employed. These include conventional and free-electron lasers. Finally, we describe the R ampersand D necessary to make either of these approaches viable and explore the use of the SLC as a test bed for a photon-photon collider of very high energy

Multi-TeV muon colliders

International Nuclear Information System (INIS)

Neuffer, D.

1986-01-01

The possibility that muons may be used in a future generation of high-energy high-luminosity μ + μ - and μ - p colliders is presented. The problem of collecting and cooling high-intensity muon bunches is discussed and ionization cooling is described. High-energy collider scenarios are outlined; muon colliders may become superior to electron colliders in the multi-TeV energy range

The development of colliders

International Nuclear Information System (INIS)

Sessler, A.M.

1997-03-01

During the period of the 50's and the 60's colliders were developed. Prior to that time there were no colliders, and by 1965 a number of small devices had worked, good understanding had been achieved, and one could speculate, as Gersh Budker did, that in a few years 20% of high energy physics would come from colliders. His estimate was an under-estimate, for now essentially all of high energy physics comes from colliders. The author presents a brief review of that history: sketching the development of the concepts, the experiments, and the technological advances which made it all possible

Tevatron Collider physics

International Nuclear Information System (INIS)

Eichten, E.J.

1990-02-01

The physics of hadron colliders is briefly reviewed. Issues for further study are presented. Particular attention is given to the physics opportunities for a high luminosity (≥ 100 pb -1 /experiment/run) Upgrade of the Tevatron Collider. 25 refs., 10 figs., 2 tabs

Stanford's linear collider

International Nuclear Information System (INIS)

Southworth, B.

1985-01-01

The peak of the construction phase of the Stanford Linear Collider, SLC, to achieve 50 GeV electron-positron collisions has now been passed. The work remains on schedule to attempt colliding beams, initially at comparatively low luminosity, early in 1987. (orig./HSI).

Analysis of S-35 labeled WR-2721 and its metabolites in biological fluids

International Nuclear Information System (INIS)

Anderson, K.W.; Krohn, K.A.; Grunbaum, Z.; Phillips, R.B.; Mahler, P.A.; Menard, T.W.; Spence, A.M.; Rasey, J.S.

1984-01-01

Studies with WR-2721 and related compounds have been hindered by the lack of a suitable assay for the drug and its major metabolites. A chromatographic method which requires no derivation for the separation and detection of WR-2721, the free thiol, its symmetrical disulfide and other mixed disulfides has been developed. The procedure involves ion-pairing for separation of ionizable compounds by causing polar molecules to become more lipophilic and hence separable using reverse phase HPLC. Detection is based upon liquid scintillation counting of S-35 incorporated during the synthesis of the parent compound. This method requires no pre-column preparation of samples and, by detecting the S-35 label, eliminates the chance that a coeluting species could interfere with detection, as might occur with post-column derivatization. This analytical technique employing radiotracers can be used to study radioprotective mechanisms by time dependent measurements of the tissue distribution and chemical form of labeled drug. Such chemical information can then be correlated with biological measures of radiation protection

When land breezes collide: Converging diurnal winds over small bodies of water

OpenAIRE

Gille, ST; Llewellyn Smith, SG

2014-01-01

© 2013 Royal Meteorological Society. Over enclosed and semi-enclosed bodies of water, the land-breeze/sea-breeze circulation is expected to be modified by the presence of opposing coastlines. These effects are studied using satellite scatterometer surface wind observations from the QuikSCAT and ADEOS-2 tandem mission from April-October 2003. Winds are studied for six bodies of water: the Red Sea, the Gulf of California, the Mediterranean, the Adriatic Sea, the Black Sea and the Caspian Sea. T...

SLAC linear collider

International Nuclear Information System (INIS)

Richter, B.; Bell, R.A.; Brown, K.L.

1980-06-01

The SLAC LINEAR COLLIDER is designed to achieve an energy of 100 GeV in the electron-positron center-of-mass system by accelerating intense bunches of particles in the SLAC linac and transporting the electron and positron bunches in a special magnet system to a point where they are focused to a radius of about 2 microns and made to collide head on. The rationale for this new type of colliding beam system is discussed, the project is described, some of the novel accelerator physics issues involved are discussed, and some of the critical technical components are described

Draft genome sequence of the intestinal parasite Blastocystis subtype 4-isolate WR1

Directory of Open Access Journals (Sweden)

Ivan Wawrzyniak

2015-06-01

Full Text Available The intestinal protistan parasite Blastocystis is characterized by an extensive genetic variability with 17 subtypes (ST1–ST17 described to date. Only the whole genome of a human ST7 isolate was previously sequenced. Here we report the draft genome sequence of Blastocystis ST4-WR1 isolated from a laboratory rodent at Singapore.

Muon collider progress

Energy Technology Data Exchange (ETDEWEB)

Noble, Robert J. FNAL

1998-08-01

Recent progress in the study of muon colliders is presented. An international collaboration consisting of over 100 individuals is involved in calculations and experiments to demonstrate the feasibility of this new type of lepton collider. Theoretical efforts are now concentrated on low-energy colliders in the 100 to 500 GeV center-of-mass energy range. Credible machine designs are emerging for much of a hypothetical complex from proton source to the final collider. Ionization cooling has been the most difficult part of the concept, and more powerful simulation tools are now in place to develop workable schemes. A collaboration proposal for a muon cooling experiment has been presented to the Fermilab Physics Advisory Committee, and a proposal for a targetry and pion collection channel experiment at Brookhaven National Laboratory is in preparation. Initial proton bunching and space-charge compensation experiments at existing hadron facilities have occurred to demonstrate proton driver feasibility.

Clinical experiences with a chemical radioprotector in tumor radiotherapy: WR-2721

International Nuclear Information System (INIS)

Tanaka, Y.

1984-01-01

Since cysteine was found to protect lethally irradiated rats, sulfhydryl compounds that provide protection of laboratory animals against lethal doses of ionizing radiations have also been given much attention. The SH compounds have been the most extensively investigated, and β-aminoethylisothiouronium (AET) and cysteamine have been selected as being representative of those drugs that are highly protective. However, clinical application is limited, as the toxicity of these compounds is high. In a series of experiments to reevaluate radioprotective agents with low toxicity, the authors found that 2-mercaptopropionylglycine (MPG) and adrenochrome monoguangylhydrazone methanesulfonate (AMM) have a potent radioprotector effect in a dose far below their toxic doses in both mice and humans. Recently, the development of effective thiophosphate derivatives of cysteamine, namely WR-2721 [S-2-(3-amino-propylaminoethyl)phosphorothioate] by the U.S. Army Medical Research and Development Commands, led to a reevaluation of these compounds and their potential in radiotherapy. Initial investigations indicated that WR-2721 provided a considerable degree of radioprotection to normal tissues. This compound provided excellent protection for normal tissues (DMF = 2-2.5) but little protection for the transplanted tumor. Thus this drug may have a differential protection in vivo and may be useful for improving the therapeutic ratio in cancer radiotherapy. The results of animal and chemical experiments in Japan are summarized herein

Linear Colliders

International Nuclear Information System (INIS)

Alcaraz, J.

2001-01-01

After several years of study e''+ e''- linear colliders in the TeV range have emerged as the major and optimal high-energy physics projects for the post-LHC era. These notes summarize the present status form the main accelerator and detector features to their physics potential. The LHC era. These notes summarize the present status, from the main accelerator and detector features to their physics potential. The LHC is expected to provide first discoveries in the new energy domain, whereas an e''+ e''- linear collider in the 500 GeV-1 TeV will be able to complement it to an unprecedented level of precision in any possible areas: Higgs, signals beyond the SM and electroweak measurements. It is evident that the Linear Collider program will constitute a major step in the understanding of the nature of the new physics beyond the Standard Model. (Author) 22 refs

Spiraling Out of Control: Three-dimensional Hydrodynamical Modeling of the Colliding Winds in η Carinae

Science.gov (United States)

Parkin, E. R.; Pittard, J. M.; Corcoran, M. F.; Hamaguchi, K.

2011-01-01

Three-dimensional adaptive mesh refinement hydrodynamical simulations of the wind-wind collision between the enigmatic supermassive star η Car and its mysterious companion star are presented which include radiative driving of the stellar winds, gravity, optically thin radiative cooling, and orbital motion. Simulations with static stars with a periastron passage separation reveal that the preshock companion star's wind speed is sufficiently reduced so that radiative cooling in the postshock gas becomes important, permitting the runaway growth of nonlinear thin-shell instabilities (NTSIs) which massively distort the wind-wind collision region (WCR). However, large-scale simulations, which include the orbital motion of the stars, show that orbital motion reduces the impact of radiative inhibition and thus increases the acquired preshock velocities. As such, the postshock gas temperature and cooling time see a commensurate increase, and sufficient gas pressure is preserved to stabilize the WCR against catastrophic instability growth. We then compute synthetic X-ray spectra and light curves and find that, compared to previous models, the X-ray spectra agree much better with XMM-Newton observations just prior to periastron. The narrow width of the 2009 X-ray minimum can also be reproduced. However, the models fail to reproduce the extended X-ray minimum from previous cycles. We conclude that the key to explaining the extended X-ray minimum is the rate of cooling of the companion star's postshock wind. If cooling is rapid then powerful NTSIs will heavily disrupt the WCR. Radiative inhibition of the companion star's preshock wind, albeit with a stronger radiation-wind coupling than explored in this work, could be an effective trigger.

SPIRALING OUT OF CONTROL: THREE-DIMENSIONAL HYDRODYNAMICAL MODELING OF THE COLLIDING WINDS IN η CARINAE

International Nuclear Information System (INIS)

Parkin, E. R.; Pittard, J. M.; Corcoran, M. F.; Hamaguchi, K.

2011-01-01

Three-dimensional adaptive mesh refinement hydrodynamical simulations of the wind-wind collision between the enigmatic supermassive star η Car and its mysterious companion star are presented which include radiative driving of the stellar winds, gravity, optically thin radiative cooling, and orbital motion. Simulations with static stars with a periastron passage separation reveal that the preshock companion star's wind speed is sufficiently reduced so that radiative cooling in the postshock gas becomes important, permitting the runaway growth of nonlinear thin-shell instabilities (NTSIs) which massively distort the wind-wind collision region (WCR). However, large-scale simulations, which include the orbital motion of the stars, show that orbital motion reduces the impact of radiative inhibition and thus increases the acquired preshock velocities. As such, the postshock gas temperature and cooling time see a commensurate increase, and sufficient gas pressure is preserved to stabilize the WCR against catastrophic instability growth. We then compute synthetic X-ray spectra and light curves and find that, compared to previous models, the X-ray spectra agree much better with XMM-Newton observations just prior to periastron. The narrow width of the 2009 X-ray minimum can also be reproduced. However, the models fail to reproduce the extended X-ray minimum from previous cycles. We conclude that the key to explaining the extended X-ray minimum is the rate of cooling of the companion star's postshock wind. If cooling is rapid then powerful NTSIs will heavily disrupt the WCR. Radiative inhibition of the companion star's preshock wind, albeit with a stronger radiation-wind coupling than explored in this work, could be an effective trigger.

The effect of 2-[(aminopropyl)amino] ethanethiol (WR 1065) on radiation-induced DNA damage and repair and cell progression in V79 cells

International Nuclear Information System (INIS)

Grdina, D.J.; Nagy, B.

1986-01-01

The radioprotector 2-[(aminopropyl)amino] ethanethiol (WR 1065) was investigated with respect to its ability to affect radiation-induced DNA damage and repair in V79 cells. At a concentration of 4mM, WR 1065 protected against the formation of single strand breaks (SSB), when present during irradiation. The protector appeared, however, to inhibit the subsequent postirradiation repair or rejoining of SSB. While repair was complete within 24h, the protector reduced the rate of repair by a factor of 3. This inhibitory effect on the rate of repair did not correlate with either measured differences in cell survival or mutagenesis. WR 1065 present in the growth medium inhibited the progression of cells through S-phase, and cell-doubling time following a 3h exposure to the protector was increased from 11 to 18h. These data are consistent with the property of thiols to inhibit DNA polymerase activity. It was concluded that, while the presence of WR 1065 during irradiation reduced SSB-DNA damage, its effect on the subsequent rejoining of these breaks could not be correlated with its observed effect on protecting against radiation-induced mutagenesis. (author)

Toxicity studies on the radioprotective agent WR-2721 in CDF1 mice and beagle dogs

International Nuclear Information System (INIS)

Palmer, T.E.; Glaza, S.M.; Dickie, B.C.; Weltman, R.H.; Greenspun, K.S.

1985-01-01

WR-2721, S-2-(3-aminopropylamino)ethylphosphorothioic acid, is used extensively to protect normal cells during the irradiation of neoplastic cells. Dose levels for human radiotherapy are based on results obtained from laboratory animal lethality and toxicity studies. WR-2721 was administered intravenously to CDF1 mice and beagle dogs. Single dose lethality studies in mice showed the average 1/10 of the lethal dose, the median lethal dose and 9/10 the lethal dose to be 508 (1523 mg/m2), 589 (1766 mg/m2), and 682 mg/kg (2047 mg/m2), respectively. The lethal dose for female mice was lower than that for males. The 1/10 lethal dose in mice was slightly toxic to dogs; 1/10 of that dose was nontoxic. The lethal dose for dogs (6000 mg/m2) was higher than that for mice (2000 mg/m2). Clinical signs of toxicosis in the single-dose mouse toxicity study were evident in the 1st week following treatment and declined during the recovery period; signs of toxicosis were transient in dogs. Acute drug-induced pathologic changes included elevated BUN and SGOT levels, lymphoid necrosis, and renal tubular degeneration in mice. These changes were evident in the 1st week following treatment, but had dissipated by study termination. Generalized vascular changes (congestion, hemorrhage, and edema) and renal tubular degeneration occurred in treated dogs that had died or were killed moribund 7 days postinjection. These findings indicate sex-dependent and interspecies variation in the toxicity of WR-2721 with acute, but reversible, pathologic changes

Photon collider at TESLA

International Nuclear Information System (INIS)

Telnov, Valery

2001-01-01

High energy photon colliders (γγ, γe) based on backward Compton scattering of laser light is a very natural addition to e + e - linear colliders. In this report, we consider this option for the TESLA project. Recent study has shown that the horizontal emittance in the TESLA damping ring can be further decreased by a factor of four. In this case, the γγ luminosity in the high energy part of spectrum can reach about (1/3)L e + e - . Typical cross-sections of interesting processes in γγ collisions are higher than those in e + e - collisions by about one order of magnitude, so the number of events in γγ collisions will be more than that in e + e - collisions. Photon colliders can, certainly, give additional information and they are the best for the study of many phenomena. The main question is now the technical feasibility. The key new element in photon colliders is a very powerful laser system. An external optical cavity is a promising approach for the TESLA project. A free electron laser is another option. However, a more straightforward solution is ''an optical storage ring (optical trap)'' with a diode pumped solid state laser injector which is today technically feasible. This paper briefly reviews the status of a photon collider based on the linear collider TESLA, its possible parameters and existing problems

"Towards a Future Linear Collider" and "The Linear Collider Studies at CERN"

CERN Document Server

CERN. Geneva

2010-01-01

During the week 18-22 October, more than 400 physicists will meet at CERN and in the CICG (International Conference Centre Geneva) to review the global progress towards a future linear collider. The 2010 International Workshop on Linear Colliders will study the physics, detectors and accelerator complex of a linear collider covering both the CLIC and ILC options. Among the topics presented and discussed will be the progress towards the CLIC Conceptual Design Report in 2011, the ILC Technical Design Report in 2012, physics and detector studies linked to these reports, and an increasing numbers of common working group activities. The seminar will give an overview of these topics and also CERN’s linear collider studies, focusing on current activities and initial plans for the period 2011-16. n.b: The Council Chamber is also reserved for this colloquium with a live transmission from the Main Auditorium.

eγ and γγ colliders

International Nuclear Information System (INIS)

Watanabe, Isamu

1994-01-01

The results that can be expected by eγ and γγ colliders in future are summarized. eγ and γγ colliders have many fine possibilities, and are the economical selection for utilizing future e + e - colliders more effectively. eγ and γγ colliders were proposed by former USSR researchers at the beginning of 1980s, but recently, the prospect of realizing future e + e - collision type linear accelerator projects has become high, they have become to be considered seriously as the option of remodeling them. The high energy photon beam of eγ and γγ colliders is obtained by causing Compton reverse scattering, irradiating laser beam to the electron beam of e + e - accelerators. The production of γ-beam is explained. As for the physics noteworthy in eγ colliders, abnormal gauge coupling, the formation of Higgs particles, excited leptons, lepto-quark, supersymmetric particles and top quark are explained. As the physics noteworthy in γγ colliders, the formation of Higgs particles which is most interesting in γγ colliders, abnormal gauge coupling, top quark, Yukawa coupling, Higgs pair formation and other particles are enumerated. The linear e + e - accelerators of TeV range including JLC have the performance to be remodeled to eγ and γγ colliders, and the prospect of realizing them has become high. Their possibility of realization is discussed. (K.I.)

Superconducting linear colliders

International Nuclear Information System (INIS)

Anon.

1990-01-01

The advantages of superconducting radiofrequency (SRF) for particle accelerators have been demonstrated by successful operation of systems in the TRISTAN and LEP electron-positron collider rings respectively at the Japanese KEK Laboratory and at CERN. If performance continues to improve and costs can be lowered, this would open an attractive option for a high luminosity TeV (1000 GeV) linear collider

Aminoquinolone WR6026 as a feasible substitute for gentian violet in Chagas' disease prophylaxis in preserved blood for transfusional purposes

Directory of Open Access Journals (Sweden)

Moraes-Souza Helio

2002-01-01

Full Text Available The search for a colorless, nontoxic and efficient drug to prevent transfusion-associated Chagas' disease (TACD has been underway unsuccessfully since 1953 when gentian violet was preconized and to date is still being used as the only in vitro trypanocidal agent. The recent findings of aminoquinolone "WR6026" as a trypanocidal agent, led the authors to study the metabolism of red cells stored with this compound, the main objective of which was to define its applicability in TACD control. Ten units of human whole blood collected in CPDA-1 were divided into two equal satellite bags. One had "WR6026" (final concentration 62.5µg/mL added and the other was used as a control, both were stored at 4ºC. At baseline, day 7, 14, 21 and 28, samples were taken for the following measurements: adenosine triphosphate (ATP, hemoglobin, electrolytes (sodium and potassium, gases (pO2 and pCO2 and osmotic fragility. The results of tests and control were analyzed through parametric t-student test. The results were similar in both groups throughout the experiment except for the level of ATP on day 14, which presented significantly higher values in the tests when compared with the controls (p = 0.012. It was concluded that WR6026 does not interfere in the preservation and probably the viability of the erythrocytes also until day 28 of storage. Consequently the authors suggest that WR6026 could emerge as a colorless substitute for gentian violet in the control of TACD in endemic areas.

The development of colliders

International Nuclear Information System (INIS)

Sessler, A.M.

1993-02-01

Don Kerst, Gersh Budker, and Bruno Touschek were the individuals, and the motivating force, which brought about the development of colliders, while the laboratories at which it happened were Stanford, MURA, the Cambridge Electron Accelerator, Orsay, Frascati, CERN, and Novosibirsk. These laboratories supported, during many years, this rather speculative activity. Of course, many hundreds of physicists contributed to the development of colliders but the men who started it, set it in the right direction, and forcefully made it happen, were Don, Gersh, and Bruno. Don was instrumental in the development of proton-proton colliders, while Bruno and Gersh spearheaded the development of electron-positron colliders. In this brief review of the history, I will sketch the development of the concepts, the experiments, and the technological developments which made possible the development of colliders. It may look as if the emphasis is on theoretical concepts, but that is really not the case, for in this field -- the physics of beams -- the theory and experiment go hand in hand; theoretical understanding and advances are almost always motivated by the need to explain experimental results or the desire to construct better experimental devices

NEW X-RAY DETECTIONS OF WNL STARS

International Nuclear Information System (INIS)

Skinner, Stephen L.; Zhekov, Svetozar A.; Güdel, Manuel; Schmutz, Werner; Sokal, Kimberly R.

2012-01-01

Previous studies have demonstrated that putatively single nitrogen-type Wolf-Rayet stars (WN stars) without known companions are X-ray sources. However, almost all WN star X-ray detections so far have been of earlier WN2-WN6 spectral subtypes. Later WN7-WN9 subtypes (also known as WNL stars) have proved more difficult to detect, an important exception being WR 79a (WN9ha). We present here new X-ray detections of the WNL stars WR 16 (WN8h) and WR 78 (WN7h). These new results, when combined with previous detections, demonstrate that X-ray emission is present in WN stars across the full range of spectral types, including later WNL stars. The two WN8 stars observed to date (WR 16 and WR 40) show unusually low X-ray luminosities (L x ) compared to other WN stars, and it is noteworthy that they also have the lowest terminal wind speeds (v ∞ ). Existing X-ray detections of about a dozen WN stars reveal a trend of increasing L x with wind luminosity L wind = (1/2)M-dot v 2 ∞ , suggesting that wind kinetic energy may play a key role in establishing X-ray luminosity levels in WN stars.

NEW X-RAY DETECTIONS OF WNL STARS

Energy Technology Data Exchange (ETDEWEB)

Skinner, Stephen L. [Center for Astrophysics and Space Astronomy (CASA), University of Colorado, Boulder, CO 80309-0389 (United States); Zhekov, Svetozar A. [Space and Solar-Terrestrial Research Institute, Moskovska str. 6, Sofia-1000 (Bulgaria); Guedel, Manuel [Department of Astronomy, University of Vienna, Tuerkenschanzstr. 17, A-1180 Vienna (Austria); Schmutz, Werner [Physikalisch-Meteorologisches Observatorium Davos (PMOD), Dorfstrasse 33, CH-7260 Davos Dorf (Switzerland); Sokal, Kimberly R., E-mail: Stephen.Skinner@colorado.edu [Department of Astronomy, University of Virginia, P.O. Box 400325, Charlottesville, VA 22904-4325 (United States)

2012-05-15

Previous studies have demonstrated that putatively single nitrogen-type Wolf-Rayet stars (WN stars) without known companions are X-ray sources. However, almost all WN star X-ray detections so far have been of earlier WN2-WN6 spectral subtypes. Later WN7-WN9 subtypes (also known as WNL stars) have proved more difficult to detect, an important exception being WR 79a (WN9ha). We present here new X-ray detections of the WNL stars WR 16 (WN8h) and WR 78 (WN7h). These new results, when combined with previous detections, demonstrate that X-ray emission is present in WN stars across the full range of spectral types, including later WNL stars. The two WN8 stars observed to date (WR 16 and WR 40) show unusually low X-ray luminosities (L{sub x} ) compared to other WN stars, and it is noteworthy that they also have the lowest terminal wind speeds (v{sub {infinity}}). Existing X-ray detections of about a dozen WN stars reveal a trend of increasing L{sub x} with wind luminosity L{sub wind} = (1/2)M-dot v{sup 2}{sub {infinity}}, suggesting that wind kinetic energy may play a key role in establishing X-ray luminosity levels in WN stars.

Searching for magnetic fields in 11 Wolf-Rayet stars: Analysis of circular polarization measurements from ESPaDOnS

Energy Technology Data Exchange (ETDEWEB)

De la Chevrotière, A.; St-Louis, N.; Moffat, A. F. J. [Centre de Recherche en Astrophysique du Québec (CRAQ), Département de physique, Université de Montréal, C.P. 6128, Succ. Centre-ville, Montréal, Québec H3C 3J7 (Canada); Collaboration: MiMeS Collaboration

2014-02-01

With recent detections of magnetic fields in some of their progenitor O stars, combined with known strong fields in their possible descendant neutron stars, it is natural to search for magnetic fields in Wolf-Rayet (WR) stars, despite the problems associated with the presence of winds enhanced by an order of magnitude over those of O stars. We continue our search among a sample of 11 bright WR stars following our introductory study in a previous paper of WR6 = EZ CMa using the spectropolarimeter ESPaDOnS at Canada-France-Hawaii Telescope, most of them in all four Stokes parameters. This sample includes six WN stars and five WC stars encompassing a range of spectral subclasses. Six are medium/long-period binaries and three show corotating interaction regions. We report no definite detections of a magnetic field in the winds in which the lines form (which is about the same distance from the center of the star as it is from the surface of the progenitor O star) for any of the eleven stars. Possible reasons and their implications are discussed. Nonetheless, the data show evidence supporting marginal detections for WR134, WR137, and WR138. According to the Bayesian analysis, the most probable field intensities are B {sub wind} ∼ 200, 130, and 80 G, respectively, with a 95.4% probability that the magnetic fields present in the observable parts of their stellar wind, if stronger, does not exceed B{sub wind}{sup max}∼1900 G, ∼1500 G, and ∼1500 G, respectively. In the case of non-detections, we report an average field strength upper limit of B{sub wind}{sup max}∼500 G.

The rise of colliding beams

International Nuclear Information System (INIS)

Richter, B.

1992-06-01

It is a particular pleasure for me to have this opportunity to review for you the rise of colliding beams as the standard technology for high-energy-physics accelerators. My own career in science has been intimately tied up in the transition from the old fixed-target technique to colliding-beam work. I have led a kind of double life both as a machine builder and as an experimenter, taking part in building and using the first of the colliding-beam machines, the Princeton-Stanford Electron-Electron Collider, and building the most recent advance in the technology, the Stanford Linear Collider. The beginning was in 1958, and in the 34 years since there has been a succession of both electron and proton colliders that have increased the available center-of-mass energy for hard collisions by more than a factor of 1000. For the historians here, I regret to say that very little of this story can be found in the conventional literature. Standard operating procedure for the accelerator physics community has been publication in conference proceedings, which can be obtained with some difficulty, but even more of the critical papers are in internal laboratory reports that were circulated informally and that may not even have been preserved. In this presentation I shall review what happened based on my personal experiences and what literature is available. I can speak from considerable experience on the electron colliders, for that is the topic in which I was most intimately involved. On proton colliders my perspective is more than of an observer than of a participant, but I have dug into the literature and have been close to many of the participants

Dedicating Fermilab's Collider

Energy Technology Data Exchange (ETDEWEB)

Anon.

1986-01-15

It was a bold move to have a fullscale dedication ceremony for the new proton-antiproton Collider at the Fermilab Tevatron on 13 October, two days before the first collisions were seen. However the particles dutifully behaved as required, and over the following weekend the Collider delivered its goods at a total energy of 1600 GeV, significantly boosting the world record for laboratory collisions.

Towards the International Linear Collider

International Nuclear Information System (INIS)

Lopez-Fernandez, Ricardo

2006-01-01

The broad physics potential of e+e- linear colliders was recognized by the high energy physics community right after the end of LEP in 2000. In 2007, the Large Hadron Collider (LHC) now under construction at CERN will obtain its first collisions. The LHC, colliding protons with protons at 14 TeV, will discover a standard model Higgs boson over the full potential mass range, and should be sensitive to new physics into the several TeV range. The program for the Linear Collider (LC) will be set in the context of the discoveries made at the LHC. All the proposals for a Linear Collider will extend the discoveries and provide a wealth of measurements that are essential for giving deeper understanding of their meaning, and pointing the way to further evolution of particle physics in the future. For the mexican groups is the right time to join such an effort

Validation of KENO V.a for criticality safety calculations involving WR-1 fast-neutron fuel arrangements

Energy Technology Data Exchange (ETDEWEB)

Gauld, I. C.

1991-07-15

The KENO V.a criticality safety code, used with the SCALE 27-energy-group ENDF/B-IV-based cross-section library, has been validated for low-enriched uranium carbide (UC) WR-1 fast-neutron (FN) fuel arrangements. Because of a lack of relevant experimental data for UC fuel in the published literature, the validation is based primarily on calculational comparisons with critical experiments for fuel types with a range of enrichments and densities that cover those of the FN UC fuel. The ability of KENO V.a to handle the unique annular pin arrangement of the WR-1 FN fuel bundle was established using a comparison with the MCNP3B code used with a continuous-energy ENDF/B-V-based cross-section library. This report is part of the AECL--10146 report series documenting the validation of the KENO V.a criticality safety code.

SLAC-Linac-Collider (SLC) Project

International Nuclear Information System (INIS)

Wiedemann, H.

1981-02-01

The proposed SLAC Linear Collider Project (SLC) and its features are described in this paper. In times of ever increasing costs for energy the electron storage ring principle is about to reach its practical limit. A new class of colliding beam beam facilities, the Linear Colliders, are getting more and more attractive and affordable at very high center-of-mass energies. The SLC is designed to be a poineer of this new class of colliding beam facilities and at the same time will serve as a valuable tool to explore the high energy physics at the level of 100 GeV in the center-of-mass system

CERN balances linear collider studies

CERN Multimedia

ILC Newsline

2011-01-01

The forces behind the two most mature proposals for a next-generation collider, the International Linear Collider (ILC) and the Compact Linear Collider (CLIC) study, have been steadily coming together, with scientists from both communities sharing ideas and information across the technology divide. In a support of cooperation between the two, CERN in Switzerland, where most CLIC research takes place, recently converted the project-specific position of CLIC Study Leader to the concept-based Linear Collider Study Leader.   The scientist who now holds this position, Steinar Stapnes, is charged with making the linear collider a viable option for CERN’s future, one that could include either CLIC or the ILC. The transition to more involve the ILC must be gradual, he said, and the redefinition of his post is a good start. Though not very much involved with superconducting radiofrequency (SRF) technology, where ILC researchers have made significant advances, CERN participates in many aspect...

Muon colliders and neutrino factories

Energy Technology Data Exchange (ETDEWEB)

Geer, S.; /Fermilab

2010-09-01

Over the last decade there has been significant progress in developing the concepts and technologies needed to produce, capture and accelerate {Omicron}(10{sup 21}) muons/year. This development prepares the way for a new type of neutrino source (Neutrino Factory) and a new type of very high energy lepton-antilepton collider (Muon Collider). This article reviews the motivation, design and R&D for Neutrino Factories and Muon Colliders.

Influence of a radioprotector WR-638 on the lymphoid compartment of the irradiated rat thymus: a flow cytometric analysis

International Nuclear Information System (INIS)

Dragojevic-Simic, V.; Colic, M.; Gasic, S.

1994-01-01

The T cell composition of the thymus of X-ray irradiated (3.5 Gy) Wistar rat protected with WR-638 was analyzed by flow cytometry using monoclonal antibodies directed to the Thy 1.1, CD43, CD2, CD5, CD4, CD8 and class I and II MHC antigens. It was shown that this dose of X-rays caused cyclic changes in thymic cellularity manifested as: primary involution (until day 2), primary regeneration (from days 2 to 14), secondary involution (from days 14 to 21) and secondary regeneration (from days 21 to 30). WR-638 reduced the magnitude of thymocyte depletion in the primary involutive phase of the irradiated thymi. (author)

The future e+e- colliders

International Nuclear Information System (INIS)

Voss, G.A.

1990-01-01

At present, the highest energy e + e - colliders are the SLC and LEP. In this paper their future improvement programs for increasing luminosity and/or energy, and the use of longitudinally polarized beams at the interaction point (IP) are discussed. An e + e - collider in the SSC tunnel does not seem to be an attractive option, on both technical and economical grounds, and with LEP, circular colliders have reached the sensible limit of size and cost. Linear colliders which have, in principle, no high energy limit, must overcome a new set of technical problems having to do with beam power limitations, emittance control, superstrong focusing at the IP, strong bunch-bunch interactions at the IP and related backgrounds

Linear collider: a preview

Energy Technology Data Exchange (ETDEWEB)

Wiedemann, H.

1981-11-01

Since no linear colliders have been built yet it is difficult to know at what energy the linear cost scaling of linear colliders drops below the quadratic scaling of storage rings. There is, however, no doubt that a linear collider facility for a center of mass energy above say 500 GeV is significantly cheaper than an equivalent storage ring. In order to make the linear collider principle feasible at very high energies a number of problems have to be solved. There are two kinds of problems: one which is related to the feasibility of the principle and the other kind of problems is associated with minimizing the cost of constructing and operating such a facility. This lecture series describes the problems and possible solutions. Since the real test of a principle requires the construction of a prototype I will in the last chapter describe the SLC project at the Stanford Linear Accelerator Center.

Linear collider: a preview

International Nuclear Information System (INIS)

Wiedemann, H.

1981-11-01

Since no linear colliders have been built yet it is difficult to know at what energy the linear cost scaling of linear colliders drops below the quadratic scaling of storage rings. There is, however, no doubt that a linear collider facility for a center of mass energy above say 500 GeV is significantly cheaper than an equivalent storage ring. In order to make the linear collider principle feasible at very high energies a number of problems have to be solved. There are two kinds of problems: one which is related to the feasibility of the principle and the other kind of problems is associated with minimizing the cost of constructing and operating such a facility. This lecture series describes the problems and possible solutions. Since the real test of a principle requires the construction of a prototype I will in the last chapter describe the SLC project at the Stanford Linear Accelerator Center

Muon muon collider: Feasibility study

International Nuclear Information System (INIS)

1996-01-01

A feasibility study is presented of a 2 + 2 TeV muon collider with a luminosity of L = 10 35 cm -2 s -1 . The resulting design is not optimized for performance, and certainly not for cost; however, it does suffice--the authors believe--to allow them to make a credible case, that a muon collider is a serious possibility for particle physics and, therefore, worthy of R and D support so that the reality of, and interest in, a muon collider can be better assayed. The goal of this support would be to completely assess the physics potential and to evaluate the cost and development of the necessary technology. The muon collider complex consists of components which first produce copious pions, then capture the pions and the resulting muons from their decay; this is followed by an ionization cooling channel to reduce the longitudinal and transverse emittance of the muon beam. The next stage is to accelerate the muons and, finally, inject them into a collider ring which has a small beta function at the colliding point. This is the first attempt at a point design and it will require further study and optimization. Experimental work will be needed to verify the validity of diverse crucial elements in the design

Superconducting super collider

International Nuclear Information System (INIS)

Limon, P.J.

1987-01-01

The Superconducting Super Collider is to be a 20 TeV per beam proton-proton accelerator and collider. Physically the SCC will be 52 miles in circumference and slightly oval in shape. The use of superconducting magnets instead of conventional cuts the circumference from 180 miles to the 52 miles. The operating cost of the SCC per year is estimated to be about $200-250 million. A detailed cost estimate of the project is roughly $3 billion in 1986 dollars. For the big collider ring, the technical cost are dominated by the magnet system. That is why one must focus on the cost and design of the magnets. Presently, the process of site selection is underway. The major R and D efforts concern superconducting dipoles. The magnets use niobium-titanium as a conductor stabilized in a copper matrix. 10 figures

Heavy leptons at hadron colliders

International Nuclear Information System (INIS)

Ohnemus, J.E.

1987-01-01

The recent advent of high energy hadron colliders capable of producing weak bosons has opened new vistas for particle physics research, including the search for a possible fourth generation heavy charged lepton, which is the primary topic of the thesis. Signals for identifying a new heavy lepton have been calculated and compared to Standard Model backgrounds. Results are presented for signals at the CERN collider, the Fermilab collider, and the proposed Superconducting Supercollider

Computing and data handling requirements for SSC [Superconducting Super Collider] and LHC [Large Hadron Collider] experiments

International Nuclear Information System (INIS)

Lankford, A.J.

1990-05-01

A number of issues for computing and data handling in the online in environment at future high-luminosity, high-energy colliders, such as the Superconducting Super Collider (SSC) and Large Hadron Collider (LHC), are outlined. Requirements for trigger processing, data acquisition, and online processing are discussed. Some aspects of possible solutions are sketched. 6 refs., 3 figs

The infrared emission features in the spectrum of the Wolf-Rayet star WR 48a

NARCIS (Netherlands)

Chiar, JE; Peeters, E; Tielens, A. G. G. M.

2002-01-01

We present the first detection of unidentified infrared (UIR) emission features at similar to6.4 and 7.9 mum in the spectrum of the dusty WC8 Wolf-Rayet star WR 48a. Based on the H-deficient nature of WC stars, we attribute the emission features to large carbonaceous molecules or amorphous carbon

COLLIDE Pro Helvetia Award

CERN Multimedia

2016-01-01

The COLLIDE Pro Helvetia Award is run in partnership with Pro Helvetia, giving the opportunity to Swiss artists to do research at CERN for three months.   From left to right: Laura Perrenoud, Marc Dubois and Simon de Diesbach. The photo shows their VR Project, +2199. Fragment.In are the winning artists of COLLIDE Pro Helvetia. They came to CERN for two months in 2015, and will now continue their last month in the laboratory. Fragment.In is a Swiss based interaction design studio. They create innovative projects, interactive installations, video and game design. Read more about COLLIDE here.

Final Focus Systems in Linear Colliders

International Nuclear Information System (INIS)

Raubenheimer, Tor

1998-01-01

In colliding beam facilities, the ''final focus system'' must demagnify the beams to attain the very small spot sizes required at the interaction points. The first final focus system with local chromatic correction was developed for the Stanford Linear Collider where very large demagnifications were desired. This same conceptual design has been adopted by all the future linear collider designs as well as the SuperConducting Supercollider, the Stanford and KEK B-Factories, and the proposed Muon Collider. In this paper, the over-all layout, physics constraints, and optimization techniques relevant to the design of final focus systems for high-energy electron-positron linear colliders are reviewed. Finally, advanced concepts to avoid some of the limitations of these systems are discussed

Photometric and polarimetric variability and mass-loss rate of the massive binary Wolf-Rayet star HDE 311884 (WN6 + 05: V)

International Nuclear Information System (INIS)

Moffat, A.F.J.; Drissen, L.; Robert, C.; Lamontagne, R.; Coziol, R.

1990-01-01

Photometric and polarimetric monitoring of the Wolf-Rayet (W-R) + O-type binary system HDE 311884 = WR 47 over many orbital cycles shows the clear effects of phase-dependent electron scattering of O-star light as the orbiting O companion shines through varying column density of W-R stellar wind material. In contrast to this wind-type eclipse, the stars themselves do not quite eclipse. Both photometry and polarimetry give a consistent estimate of the mass-loss rate of the W-R component: at about 0.00003 solar mass/yr. The orbital inclination, i = 70 deg, along with the previously published velocity orbit, yields high masses: M(WN6) = 48 solar masses and M(O5:V) = 57 solar masses. 33 refs

Collider Physics an Experimental Introduction

International Nuclear Information System (INIS)

Elvezio Pagliarone, Carmine

2011-01-01

This paper reviews shortly a small part of the contents of a set of lectures, presented at the XIV International School of Particles and Fields in Morelia, state of Michoacan, Mexico, during November 2010. The main goal of those lectures was to introduce students to some of the basic ideas and tools required for experimental and phenomenological analysis of collider data. In particular, after an introduction to the scientific motivations, that drives the construction of powerful accelerator complexes, and the need of reaching high center of mass energies and luminosities, some basic concept about collider particle detectors will be discussed. A status about the present running colliders and collider experiments as well as future plans and research and development is also given.

Gamma rays from active regions in the galaxy: the possible contribution of stellar winds

International Nuclear Information System (INIS)

Cesarsky, C.J.; Montmerle, Thierry.

1982-08-01

Massive stars release a considerable amount of mechanical energy in the form of strong stellar winds. A fraction of this energy may be transferred to relativistic cosmic rays by diffusive shock acceleration at the wind boundary, and/or in the expanding, turbulent wind itself. Massive stars are most frequently found in OB associations, surrounded by H II regions lying at the edge of dense molecular clouds. The interaction of the freshly accelerated particles with matter gives rise to #betta#-ray emission. In this paper, we first briefly review the current knowledge on the energetics of strong stellar winds from O and Wolf-Rayet stars, as well as from T Tauri stars. Taking into account the finite lifetime of these stars, we then proceed to show that stellar winds dominate the energetics of OB associations during the first 4 to 6 million years, after which supernovae take over. In the solar neighborhood, the star formation rate is constant, and a steady-state situation prevails, in which the supernova contribution is found to be dominant. A small, but meaningful fraction of the CO S-B #betta#-ray sources may be fueled by WR and O stellar winds in OB associations, while the power released by T Tauri stars alone is perhaps insufficient to account for the #betta#-ray emission of nearby dark clouds. Finally, we discuss some controversial aspects of the physics of particle acceleration by stellar winds

SLAC linear collider and a few ideas on future linear colliders

International Nuclear Information System (INIS)

Loew, G.A.

1984-04-01

This paper comes in two parts. The first part is a progress report on the SLAC Linear Collider (SLC) with emphasis on those systems which are of special interest to linear accelerator designers; it sets the stage for a number of contributed papers on specific topics which are also presented at this conference. The second part presents some ideas which are of interest to the design of future linear colliders of higher energies

Muon muon collider: Feasibility study

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-06-18

A feasibility study is presented of a 2 + 2 TeV muon collider with a luminosity of L = 10{sup 35} cm{sup {minus}2} s{sup {minus}1}. The resulting design is not optimized for performance, and certainly not for cost; however, it does suffice--the authors believe--to allow them to make a credible case, that a muon collider is a serious possibility for particle physics and, therefore, worthy of R and D support so that the reality of, and interest in, a muon collider can be better assayed. The goal of this support would be to completely assess the physics potential and to evaluate the cost and development of the necessary technology. The muon collider complex consists of components which first produce copious pions, then capture the pions and the resulting muons from their decay; this is followed by an ionization cooling channel to reduce the longitudinal and transverse emittance of the muon beam. The next stage is to accelerate the muons and, finally, inject them into a collider ring which has a small beta function at the colliding point. This is the first attempt at a point design and it will require further study and optimization. Experimental work will be needed to verify the validity of diverse crucial elements in the design.

NOVOSIBIRSK/STANFORD: colliding linac beams

International Nuclear Information System (INIS)

Anon.

1979-01-01

Plans to use colliding beams from linear accelerators are being considered at Novosibirsk and Stanford. The VLEPP scheme proposed for Novosibirsk and the Stanford single pass collider scheme are described. (W.D.L.).

Superconducting magnets for a muon collider

International Nuclear Information System (INIS)

Green, M.A.

1996-01-01

The existence of a muon collider will be dependent on the use of superconducting magnets. Superconducting magnets for the μ - μ + collider will be found in the following locations: the π - π + capture system, the muon phase rotation system, the muon cooling system, the recirculating acceleration system, the collider ring, and the collider detector system. This report describes superconducting magnets for each of these sections except the detector. In addition to superconducting magnets, superconducting RF cavities will be found in the recirculating accelerator sections and the collider ring. The use of superconducting magnets is dictated by the need for high magnetic fields in order to reduce the length of various machine components. The performance of all of the superconducting magnets will be affected the energy deposited from muon decay products. (orig.)

Avian collision risk models for wind energy impact assessments

International Nuclear Information System (INIS)

Masden, E.A.; Cook, A.S.C.P.

2016-01-01

With the increasing global development of wind energy, collision risk models (CRMs) are routinely used to assess the potential impacts of wind turbines on birds. We reviewed and compared the avian collision risk models currently available in the scientific literature, exploring aspects such as the calculation of a collision probability, inclusion of stationary components e.g. the tower, angle of approach and uncertainty. 10 models were cited in the literature and of these, all included a probability of collision of a single bird colliding with a wind turbine during passage through the rotor swept area, and the majority included a measure of the number of birds at risk. 7 out of the 10 models calculated the probability of birds colliding, whilst the remainder used a constant. We identified four approaches to calculate the probability of collision and these were used by others. 6 of the 10 models were deterministic and included the most frequently used models in the UK, with only 4 including variation or uncertainty in some way, the most recent using Bayesian methods. Despite their appeal, CRMs have their limitations and can be ‘data hungry’ as well as assuming much about bird movement and behaviour. As data become available, these assumptions should be tested to ensure that CRMs are functioning to adequately answer the questions posed by the wind energy sector. - Highlights: • We highlighted ten models available to assess avian collision risk. • Only 4 of the models included variability or uncertainty. • Collision risk models have limitations and can be ‘data hungry’. • It is vital that the most appropriate model is used for a given task.

Avian collision risk models for wind energy impact assessments

Energy Technology Data Exchange (ETDEWEB)

Masden, E.A., E-mail: elizabeth.masden@uhi.ac.uk [Environmental Research Institute, North Highland College-UHI, University of the Highlands and Islands, Ormlie Road, Thurso, Caithness KW14 7EE (United Kingdom); Cook, A.S.C.P. [British Trust for Ornithology, The Nunnery, Thetford IP24 2PU (United Kingdom)

2016-01-15

With the increasing global development of wind energy, collision risk models (CRMs) are routinely used to assess the potential impacts of wind turbines on birds. We reviewed and compared the avian collision risk models currently available in the scientific literature, exploring aspects such as the calculation of a collision probability, inclusion of stationary components e.g. the tower, angle of approach and uncertainty. 10 models were cited in the literature and of these, all included a probability of collision of a single bird colliding with a wind turbine during passage through the rotor swept area, and the majority included a measure of the number of birds at risk. 7 out of the 10 models calculated the probability of birds colliding, whilst the remainder used a constant. We identified four approaches to calculate the probability of collision and these were used by others. 6 of the 10 models were deterministic and included the most frequently used models in the UK, with only 4 including variation or uncertainty in some way, the most recent using Bayesian methods. Despite their appeal, CRMs have their limitations and can be ‘data hungry’ as well as assuming much about bird movement and behaviour. As data become available, these assumptions should be tested to ensure that CRMs are functioning to adequately answer the questions posed by the wind energy sector. - Highlights: • We highlighted ten models available to assess avian collision risk. • Only 4 of the models included variability or uncertainty. • Collision risk models have limitations and can be ‘data hungry’. • It is vital that the most appropriate model is used for a given task.

Hadron collider physics at UCR

International Nuclear Information System (INIS)

Kernan, A.; Shen, B.C.

1997-01-01

This paper describes the research work in high energy physics by the group at the University of California, Riverside. Work has been divided between hadron collider physics and e + -e - collider physics, and theoretical work. The hadron effort has been heavily involved in the startup activities of the D-Zero detector, commissioning and ongoing redesign. The lepton collider work has included work on TPC/2γ at PEP and the OPAL detector at LEP, as well as efforts on hadron machines

Physics at a future collider beyond the LHC and a TeV class linear collider

CERN Multimedia

CERN. Geneva

2003-01-01

After the LHC will have probed the physics at the TeV frontier, new generations of colliders capable of reaching into the multi-TeV energy domain will need to be considered. Concepts for both high energy e+e- linear colliders and muon storage rings have been proposed as well as hadron colliders. Highly challenging R&D programs are presently pursued to demonstrate their principles. The definition of a physics programme in the multi-TeV range still requires essential data that is likely to become available only after the first years of LHC operation and, possibly, also the results from a TeV-class linear collider. At present we have to envisage several possible scenarios for the fundamental questions to be addressed by collider experiments in the next decade, to guide the choices in the accelerator designs and parameters. After a brief review of the main accelerator projects and the present status of their R&D, I shall discuss the main signatures of the physics of possible relevance in relation to the e...

Stable massive particles at colliders

Energy Technology Data Exchange (ETDEWEB)

Fairbairn, M.; /Stockholm U.; Kraan, A.C.; /Pennsylvania U.; Milstead, D.A.; /Stockholm U.; Sjostrand, T.; /Lund U.; Skands, P.; /Fermilab; Sloan, T.; /Lancaster U.

2006-11-01

We review the theoretical motivations and experimental status of searches for stable massive particles (SMPs) which could be sufficiently long-lived as to be directly detected at collider experiments. The discovery of such particles would address a number of important questions in modern physics including the origin and composition of dark matter in the universe and the unification of the fundamental forces. This review describes the techniques used in SMP-searches at collider experiments and the limits so far obtained on the production of SMPs which possess various colour, electric and magnetic charge quantum numbers. We also describe theoretical scenarios which predict SMPs, the phenomenology needed to model their production at colliders and interactions with matter. In addition, the interplay between collider searches and open questions in cosmology such as dark matter composition are addressed.

TeV e+e- linear colliders

International Nuclear Information System (INIS)

Le Duff, J.

1987-12-01

The basic philosophy and performance and technical constraints of linear e + e - colliders at TeV energies are summarized. Collider luminosity, pinch effects due to beam interaction, beam-beam bremsstrahlung, and typical parameters for an e + e - linear collider are discussed. Accelerating structures, HF power sources, electron guns, positron production, and storage rings are considered [fr

The SLAC linear collider

International Nuclear Information System (INIS)

Richter, B.

1985-01-01

A report is given on the goals and progress of the SLAC Linear Collider. The author discusses the status of the machine and the detectors and give an overview of the physics which can be done at this new facility. He also gives some ideas on how (and why) large linear colliders of the future should be built

Potential impacts of wind turbines on birds at North Cape, Prince Edward Island

Energy Technology Data Exchange (ETDEWEB)

Kingsley, A.; Whitman, B.

2001-12-13

As the number of new wind power generating stations in Canada grows, so do concerns regarding the environmental impact of turbines on birds, particularly on raptors and migrating songbirds. These birds are generally at greatest risk of injury or death from turbines, but the impact of these structures on all bird species must be considered on a site-by-site basis. Disturbance to breeding and wintering as a result of turbines must be better researched. This report reviews the literature on the effects of wind turbines on birds, with reference to the North Cape, Prince Edward Island. It recommends ways to reduce potential impacts of turbines on birds in that area, and suggests a program whereby the potential effects of wind turbines on birds can be monitored. The bird groups likely to be seen at North Cape include water birds, raptors, songbirds, and 5 bird species that are considered to be provincially rare. The main causes of bird mortality at wind powered energy facilities are birds flying into rotating turbine blades. Migrating birds are attracted to warning lights on the turbines and collide with the structures and they also collide with the power lines connected to the station. Poor weather conditions, such as fog, increase the occurrence of collisions with towers. Several studies have shown that most migrating and wintering bird species alter their flight paths to avoid turbines. Studies also indicate that bird mortalities at wind energy facilities are not biologically significant and that impacts are not likely to be significant if wind turbines are located in areas of poor habitat and low bird densities. 61 refs., 1 tab., 1 fig.

Hadron collider physics at UCR

Energy Technology Data Exchange (ETDEWEB)

Kernan, A.; Shen, B.C.

1997-07-01

This paper describes the research work in high energy physics by the group at the University of California, Riverside. Work has been divided between hadron collider physics and e{sup +}-e{sup {minus}} collider physics, and theoretical work. The hadron effort has been heavily involved in the startup activities of the D-Zero detector, commissioning and ongoing redesign. The lepton collider work has included work on TPC/2{gamma} at PEP and the OPAL detector at LEP, as well as efforts on hadron machines.

B factory with hadron colliders

International Nuclear Information System (INIS)

Lockyer, N.S.

1990-01-01

The opportunities to study B physics in a hadron collider are discussed. Emphasis is placed on the technological developments necessary for these experiments. The R and D program of the Bottom Collider Detector group is reviewed. (author)

Prospects for Future Collider Physics

CERN Document Server

Ellis, John

2016-10-20

One item on the agenda of future colliders is certain to be the Higgs boson. What is it trying to tell us? The primary objective of any future collider must surely be to identify physics beyond the Standard Model, and supersymmetry is one of the most studied options. it Is supersymmetry waiting for us and, if so, can LHC Run 2 find it? The big surprise from the initial 13-TeV LHC data has been the appearance of a possible signal for a new boson X with a mass ~750 GeV. What are the prospects for future colliders if the X(750) exists? One of the most intriguing possibilities in electroweak physics would be the discovery of non-perturbative phenomena. What are the prospects for observing sphalerons at the LHC or a future collider?

Physics at Future Hadron Colliders

CERN Document Server

Baur, U.; Parsons, J.; Albrow, M.; Denisov, D.; Han, T.; Kotwal, A.; Olness, F.; Qian, J.; Belyaev, S.; Bosman, M.; Brooijmans, G.; Gaines, I.; Godfrey, S.; Hansen, J.B.; Hauser, J.; Heintz, U.; Hinchliffe, I.; Kao, C.; Landsberg, G.; Maltoni, F.; Oleari, C.; Pagliarone, C.; Paige, F.; Plehn, T.; Rainwater, D.; Reina, L.; Rizzo, T.; Su, S.; Tait, T.; Wackeroth, D.; Vataga, E.; Zeppenfeld, D.

2001-01-01

We discuss the physics opportunities and detector challenges at future hadron colliders. As guidelines for energies and luminosities we use the proposed luminosity and/or energy upgrade of the LHC (SLHC), and the Fermilab design of a Very Large Hadron Collider (VLHC). We illustrate the physics capabilities of future hadron colliders for a variety of new physics scenarios (supersymmetry, strong electroweak symmetry breaking, new gauge bosons, compositeness and extra dimensions). We also investigate the prospects of doing precision Higgs physics studies at such a machine, and list selected Standard Model physics rates.

Survival of irradiated mice treated with WR-151327, synthetic trehalose dicorynomycolate, or ofloxacin

Science.gov (United States)

Ledney, G. D.; Elliott, T. B.; Landauer, M. R.; Vigneulle, R. M.; Henderson, P. L.; Harding, R. A.; Tom, S. P.

1994-10-01

Spaceflight personnel need treatment options that would enhance survival from radiation and would not disrupt task performance. Doses of prophylactic or therapeutic agents known to induce significant short-term (30-day) survival with minimal behavioral (locomotor) changes were used for 180-day survival studies. In protection studies, groups of mice were treated with the phosphorothioate WR-151327 (200 mg/kg, 25% of the LD10) or the immunomodulator, synthetic trehalose dicorynomycolate (S-TDCM; 8 mg/kg), before lethal irradiation with reactor-generated fission neutrons and γ-rays (n/γ = 1) or 60Co γ-rays. In therapy studies, groups of mice received either S-TDCM, the antimicrobial ofloxacin, or S-TDCM plus ofloxacin after irradiation. For WR-151327 treated-mice, survival at 180 days for n/γ = 1 and γ-irradiated mice was 90% and 92%, respectively; for S-TDCM (protection), 57% and 78%, respectively; for S-TDCM (therapy), 20% and 25%, respectively; for ofloxacin, 38% and 5%, respectively; for S-TDCM combined with ofloxacin, 30% and 30%, respectively; and for saline, 8% and 5%, respectively. Ofloxacin or combined ofloxacin and S-TDCM increased survival from the gram-negative bacterial sepsis that predominated in n/γ = 1) irradiated mice. The efficacies of the treatments depended on radiation quality, treatment agent and its mode of use, and microflora of the host.

HIGH ENERGY PHYSICS POTENTIAL AT MUON COLLIDERS

International Nuclear Information System (INIS)

PARSA, Z.

2000-01-01

In this paper, high energy physics possibilities and future colliders are discussed. The μ + μ - collider and experiments with high intensity muon beams as the stepping phase towards building Higher Energy Muon Colliders (HEMC) are briefly reviewed and encouraged

Structure design and experimental appraisal of the drag force type vertical axis wind turbine

International Nuclear Information System (INIS)

Kim, Dong Keon; Keum, Jong Yoon; Yoon, Soon Hyun

2006-01-01

Experiments were conducted to estimate the performance of drag force type vertical axis wind turbine with an opening-shutting rotor. It was operated by the difference in drag force generated on both sides of the blades. The rotational speed was measured by a tachometer in a wind tunnel and the tunnel wind speed was measured by using a pitot-static tube and a micro manometer. The performance test for a prototype was accomplished by calculating power, power coefficient, torque coefficient from the measurement of torque and rpm by a dynamometer controller. Various design parameters, such as the number of blades(B), blade aspect ratio(W/R), angle of blades(α) and drag coefficient acting on a blade, were considered for optimal conditions. At the experiment of miniature model, maximum efficiency was found at N=15, α=60 .deg. and W/R=0.32. The measured test variables were power, torque, rotational speed, and wind speeds. The data presented are in the form of power and torque coefficients as a function of tip-speed ratio V/U. Maximum power was found in case of Ω=0.33, when the power and torque coefficient were 0.14 and 0.37 respectively. Comparing model test with prototype test, similarity law by advance ratio for vertical axis wind turbine was confirmed

Muon Muon Collider: Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Gallardo, J.C.; Palmer, R.B.; /Brookhaven; Tollestrup, A.V.; /Fermilab; Sessler, A.M.; /LBL, Berkeley; Skrinsky, A.N.; /Novosibirsk, IYF; Ankenbrandt, C.; Geer, S.; Griffin, J.; Johnstone, C.; Lebrun, P.; McInturff, A.; Mills, Frederick E.; Mokhov, N.; Moretti, A.; Neuffer, D.; Ng, K.Y.; Noble, R.; Novitski, I.; Popovic, M.; Qian, C.; Van Ginneken, A. /Fermilab /Brookhaven /Wisconsin U., Madison /Tel Aviv U. /Indiana U. /UCLA /LBL, Berkeley /SLAC /Argonne /Sobolev IM, Novosibirsk /UC, Davis /Munich, Tech. U. /Virginia U. /KEK, Tsukuba /DESY /Novosibirsk, IYF /Jefferson Lab /Mississippi U. /SUNY, Stony Brook /MIT /Columbia U. /Fairfield U. /UC, Berkeley

2012-04-05

A feasibility study is presented of a 2 + 2 TeV muon collider with a luminosity of L = 10{sup 35} cm{sup -2}s{sup -1}. The resulting design is not optimized for performance, and certainly not for cost; however, it does suffice - we believe - to allow us to make a credible case, that a muon collider is a serious possibility for particle physics and, therefore, worthy of R and D support so that the reality of, and interest in, a muon collider can be better assayed. The goal of this support would be to completely assess the physics potential and to evaluate the cost and development of the necessary technology. The muon collider complex consists of components which first produce copious pions, then capture the pions and the resulting muons from their decay; this is followed by an ionization cooling channel to reduce the longitudinal and transverse emittance of the muon beam. The next stage is to accelerate the muons and, finally, inject them into a collider ring wich has a small beta function at the colliding point. This is the first attempt at a point design and it will require further study and optimization. Experimental work will be needed to verify the validity of diverse crucial elements in the design. Muons because of their large mass compared to an electron, do not produce significant synchrotron radiation. As a result there is negligible beamstrahlung and high energy collisions are not limited by this phenomena. In addition, muons can be accelerated in circular devices which will be considerably smaller than two full-energy linacs as required in an e{sup +} - e{sup -} collider. A hadron collider would require a CM energy 5 to 10 times higher than 4 TeV to have an equivalent energy reach. Since the accelerator size is limited by the strength of bending magnets, the hadron collider for the same physics reach would have to be much larger than the muon collider. In addition, muon collisions should be cleaner than hadron collisions. There are many detailed particle

Collide@CERN Geneva

CERN Multimedia

CERN. Geneva; Kieffer, Robert; Blas Temino, Diego; Bertolucci, Sergio; Mr. Decelière, Rudy; Mr. Hänni, Vincent

2014-01-01

CERN, the Republic and Canton of Geneva, and the City of Geneva are delighted to invite you to “Collide@CERN Geneva Music”. Come to the public lecture about collisions between music and particle physics by the third winners of Collide@CERN Geneva, Vincent Hänni & Rudy Decelière, and their scientific inspiration partners, Diego Blas and Robert Kieffer. The event marks the beginning of their residency at CERN, and will be held at the CERN Globe of Science and Innovation on 16 October 2014 at 19.00. Doors will open at 18.30.

Feedback systems for linear colliders

CERN Document Server

Hendrickson, L; Himel, Thomas M; Minty, Michiko G; Phinney, N; Raimondi, Pantaleo; Raubenheimer, T O; Shoaee, H; Tenenbaum, P G

1999-01-01

Feedback systems are essential for stable operation of a linear collider, providing a cost-effective method for relaxing tight tolerances. In the Stanford Linear Collider (SLC), feedback controls beam parameters such as trajectory, energy, and intensity throughout the accelerator. A novel dithering optimization system which adjusts final focus parameters to maximize luminosity contributed to achieving record performance in the 1997-98 run. Performance limitations of the steering feedback have been investigated, and improvements have been made. For the Next Linear Collider (NLC), extensive feedback systems are planned as an intregal part of the design. Feedback requiremetns for JLC (the Japanese Linear Collider) are essentially identical to NLC; some of the TESLA requirements are similar but there are significant differences. For NLC, algorithms which incorporate improvements upon the SLC implementation are being prototyped. Specialized systems for the damping rings, rf and interaction point will operate at hi...

FERMILAB: Collider detectors -2

International Nuclear Information System (INIS)

Anon.

1993-01-01

Last month's edition (April, page 12) included a status report on data collection and preliminary physics results from the 'newcomer' DO detector at Fermilab's Tevatron proton-antiproton collider. This time the spotlight falls in the Veteran' CDF detector, in action since 1985 and meanwhile significantly upgraded. Meanwhile the Tevatron collider continues to improve, with record collision rates

Colliding almost-plane gravitational waves: Colliding plane waves and general properties of almost-plane-wave spacetimes

International Nuclear Information System (INIS)

Yurtsever, U.

1988-01-01

It is well known that when two precisely plane-symmetric gravitational waves propagating in an otherwise flat background collide, they focus each other so strongly as to produce a curvature singularity. This paper is the first of several devoted to almost-plane gravitational waves and their collisions. Such waves are more realistic than plane waves in having a finite but very large transverse size. In this paper we review some crucial features of the well-known exact solutions for colliding plane waves and we argue that one of these features, the breakdown of ''local inextendibility'' can be regarded as nongeneric. We then introduce a new framework for analyzing general colliding plane-wave spacetimes; we give an alternative proof of a theorem due to Tipler implying the existence of singularities in all generic colliding plane-wave solutions; and we discuss the fact that the recently constructed Chandrasekhar-Xanthopoulos colliding plane-wave solutions are not strictly plane symmetric and thus do not satisfy the conditions and the conclusion of Tipler's theorem

Multibunch operation in the Tevatron Collider

International Nuclear Information System (INIS)

Holt, J.A.; Finley, D.A.; Bharadwaj, V.

1993-05-01

The Tevatron Collider at Fermilab is the world's highest energy hadron collider, colliding protons with antiprotons at a center of mass energy of 1800 GeV. At present six proton bunches collide with six antiproton bunches to generate luminosities of up to 9 x 10 30 cm -2 s -1 . It is estimated that to reach luminosities significantly greater than 10 31 cm -2 s -1 while minimizing the number of interactions per crossing, the number of bunches will have to be increased. Thirty-six bunch operation looks like the most promising plan. This paper looks at the strategies for increasing the number of particle bunches, the new hardware that needs to be designed and changes to the operating mode in filling the Tevatron. An interactive program which simulates the filling of the Tevatron collider is also presented. The time scale for multibunch operation and progress towards running greater than six bunches is given in this paper

Progress on $e^{+}e^{-}$ linear colliders

CERN Multimedia

CERN. Geneva. Audiovisual Unit; Siemann, Peter

2002-01-01

Physics issues. The physics program will be reviewed for e+e- linear colliders in the TeV energy range. At these prospective facilities central issues of particle physics can be addressed, the problem of mass, unification and structure of space-time. In this context the two lectures will focus on analyses of the Higgs mechanism, supersymmetry and extra space dimensions. Moreover, high-precision studies of the top-quark and the gauge boson sector will be discussed. Combined with LHC results, a comprehensive picture can be developed of physics at the electroweak scale and beyond. Designs and technologies (R. Siemann - 29, 30, 31 May) The physics and technologies of high energy linear colliders will be reviewed. Fundamental concepts of linear colliders will be introduced. They will be discussed in: the context of the Stanford Linear Collider where many ideas changed and new ones were developed in response to operational experience. the requirements for future linear colliders. The different approaches for reac...

Physics at Hadronic Colliders (4/4)

CERN Multimedia

CERN. Geneva

2008-01-01

Hadron colliders are often called "discovery machines" since they produce the highest mass particles and thus give often the best chance to discover new high mass particles. Currently they are particularly topical since the Large Hadron Collider will start operating later this year, increasing the centre-of-mass energy by a factor of seven compared to the current highest energy collider, the Tevatron. I will review the benefits and challenges of hadron colliders and review some of the current physics results from the Tevatron and give an outlook to the future results we are hoping for at the LHC. Prerequisite knowledge: Introduction to Particle Physics (F. Close), Detectors (W. Riegler, at least mostly) and The Standard Model (A. Pich)

Physics at Hadronic Colliders (1/4)

CERN Multimedia

CERN. Geneva

2008-01-01

Hadron colliders are often called "discovery machines" since they produce the highest mass particles and thus give often the best chance to discover new high mass particles. Currently they are particularly topical since the Large Hadron Collider will start operating later this year, increasing the centre-of-mass energy by a factor of seven compared to the current highest energy collider, the Tevatron. I will review the benefits and challenges of hadron colliders and review some of the current physics results from the Tevatron and give an outlook to the future results we are hoping for at the LHC. Prerequisite knowledge: Introduction to Particle Physics (F. Close), Detectors (W. Riegler, at least mostly) and The Standard Model (A. Pich)

Physics at Hadronic Colliders (2/4)

CERN Multimedia

CERN. Geneva

2008-01-01

Hadron colliders are often called "discovery machines" since they produce the highest mass particles and thus give often the best chance to discover new high mass particles. Currently they are particularly topical since the Large Hadron Collider will start operating later this year, increasing the centre-of-mass energy by a factor of seven compared to the current highest energy collider, the Tevatron. I will review the benefits and challenges of hadron colliders and review some of the current physics results from the Tevatron and give an outlook to the future results we are hoping for at the LHC. Prerequisite knowledge: Introduction to Particle Physics (F. Close), Detectors (W. Riegler, at least mostly) and The Standard Model (A. Pich)

Physics at Hadronic Colliders (3/4)

CERN Multimedia

CERN. Geneva

2008-01-01

Hadron colliders are often called "discovery machines" since they produce the highest mass particles and thus give often the best chance to discover new high mass particles. Currently they are particularly topical since the Large Hadron Collider will start operating later this year, increasing the centre-of-mass energy by a factor of seven compared to the current highest energy collider, the Tevatron. I will review the benefits and challenges of hadron colliders and review some of the current physics results from the Tevatron and give an outlook to the future results we are hoping for at the LHC. Prerequisite knowledge: Introduction to Particle Physics (F. Close), Detectors (W. Riegler, at least mostly) and The Standard Model (A. Pich)

Future Hadron Colliders

CERN Document Server

Keil, Eberhard

1998-01-01

Plans for future hadron colliders are presented, and accelerator physics and engineering aspects common to these machines are discussed. The Tevatron is presented first, starting with a summary of the achievements in Run IB which finished in 1995, followed by performance predictions for Run II which will start in 1999, and the TeV33 project, aiming for a peak luminosity $L ~ 1 (nbs)^-1$. The next machine is the Large Hadron Collider LHC at CERN, planned to come into operation in 2005. The last set of machines are Very Large Hadron Colliders which might be constructed after the LHC. Three variants are presented: Two machines with a beam energy of 50 TeV, and dipole fields of 1.8 and 12.6 T in the arcs, and a machine with 100 TeV and 12 T. The discussion of accelerator physics aspects includes the beam-beam effect, bunch spacing and parasitic collisions, and the crossing angle. The discussion of the engineering aspects covers synchrotron radiation and stored energy in the beams, the power in the debris of the p...

The effect of the Sep wind park near Oosterbierum, Friesland, The Netherlands, on birds

International Nuclear Information System (INIS)

Winkelman, J.E.

1992-01-01

The title study concerns the period 1984-1991. The wind park consists of 18 three-bladed 300 kW horizontal axis wind turbines of 35 meters height, and a rotor diameter of 30 meters, seven meteorological towers, and three cluster and control buildings. Aspects studied included disturbance of breeding, resting or feeding, and migrating birds, behavior of birds approaching the wind turbines during the day and night, and bird victims due to collision with the wind turbines and the meteorological towers. This report deals with the results of searches for dead birds killed as a consequence of collisions with obstacles in the wind park in the spring of 1986-1991 and in the autumn of 1986-1988 and 1991. During the six spring periods and four autumn periods searches were made on 642 different days during which 2907 times an obstacle was searched for dead birds. During these days 76 birds were found (25 species), of which 36% were certainly or very probably killed as a result from a collision with a wind turbine, and 22% were possibly so. Of 34% the cause of death was unknown, and 7% died from other causes. Of the 76 birds found 17% were wounded but still alive. There were no nights with large kills. Also attention is paid to the distribution of the bird victims over the wind park area, their individual positions with regard to the obstacles, and the weather conditions in relation to the number of victims at a certain day. On average less than 0.1% of the birds passing the wind park during the night collided with an obstacle in the wind park, and less than 0.01% did so when the diurnal migration is included. When all resting and feeding birds are also added less than 0.008% collided in autumn (in spring less than 0.06%, breeding birds included). When the possible collisions are included these figures are 0.2%, 0.02%, 0.01% and 0.1% respectively. 9 figs., 22 tabs., 19 app., 83 refs

Mortality of radio collared willow ptarmigan in Smoela wind-power plant

Energy Technology Data Exchange (ETDEWEB)

Pedersen, Hans Chr.; Broeseth, Henrik; Nilsen, Erlend B.; Sandercock, Brett K.; Bevanger, Kjetil

2011-07-01

Full text: In the project Pre- and post-construction studies of conflicts between birds and wind turbines in coastal Norway (BirdWind), Smoela willow ptarmigan (Lagopus lagopus variegatus) has been one of the species studied. This sub-species represent gallinaceous birds, known to be bad flyers susceptible to collide with artificial structures, e.g. power lines. However, the possible impact of a wind-power plant on survival and behaviour in a willow ptarmigan population was unknown. The objectives of the study were therefore rather wide; to study direct and indirect effects of wind turbines on willow ptarmigan behaviour, habitat selection, reproduction and survival in areas where wind-power plants are established. To collect data on habitat selection, movements, collision risks, avoidance behaviour, survival and general population dynamic parameters, willow ptarmigan were radio-tagged in 2008-2010, using traditional VHF-transmitters (Holohill) with mortality switch, necklace mount, 12 g, lasting for approximately 24 months. Due to low population density and only occasional snow cover, a method using strong lights, dipnet and car was used to catch birds. In total, 34 willow ptarmigan were caught (19 males and 15 females). All birds were caught inside the wind-power plant area (WPA). The birds were radio-tracked at irregular intervals and almost all birds, when found, was located within the WPA. All carcasses of dead birds were examined. When possible, cause of death was determined as; predation (raptor), collision, unknown, other. In total, 28 of the radio-tagged birds have died since January 2008. A Kaplan-Meier analysis of cumulative survival rates, show an exceptionally low survival (<30%). Unlike other willow ptarmigan populations most of the mortality takes place during winter, from December throughout March. Although a thorough analysis of mortality causes has yet not been carried out, a majority of the birds have probably been killed by avian predators and to

Properties of hot luminous stars; Proceedings of the First Boulder-Munich Workshop, Boulder, CO, Aug. 6-11, 1988

International Nuclear Information System (INIS)

Garmany, C.D.

1990-01-01

Various papers on the properties of hot luminous stars are presented. Individual topics addressed include: problems in photometry of early-type stars; digital optical morphology of OB spectra; massive-star content of the Magellanic Clouds; observations of massive OB stars; LSS 3074, a new double-lined early O-type binary; non-LTE line blanketing with elements 1-28; non-LTE analysis of four PG1159 stars; rescaling method for model atmospheres of hot stars; stellar wind albedo effects on hot photospheres; atomic data and models for hot star abundance determinations; ring nebulae analysis as a probe for WR atmospheres; coordinated observations of P Cygni; radiation-driven winds of hot luminous stars; winds of O stars: velocities and ionization; methods of radiative transfer in expanding atmospheres; mass loss from extragalactic O stars; H-alpha observations of O- and B-type stars; applicability of steady models for hot-star winds; mass of the O6Iaf star HD 153919; stellar winds in Beta Lyrae; models of WR stars; observational abundances of WR stars, the all-variable WC7 binary HD193793

The photon collider at TESLA

Czech Academy of Sciences Publication Activity Database

Badelek, B.; Bloechinger, C.; Blümlein, J.; Boos, E.; Brinkman, R.; Burkhardt, H.; Bussey, P.; Carimalo, C.; Chýla, Jiří; Ciftci, A.K.

2004-01-01

Roč. 19, č. 30 (2004), s. 5097-5186 ISSN 0217-751X Institutional research plan: CEZ:AV0Z1010920 Keywords : photon collider * linear collider * gamma-gamma * photon-photon * photon electron * Compton scattering Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 1.054, year: 2004

The Contribution of Stellar Winds to Cosmic Ray Production

Science.gov (United States)

Seo, Jeongbhin; Kang, Hyesung; Ryu, Dongsu

2018-04-01

Massive stars blow powerful stellar winds throughout their evolutionary stages from the main sequence to Wolf-Rayet phases. The wind mechanical energy of a massive star deposited to the interstellar medium can be comparable to the explosion energy of a core-collapse supernova that detonates at the end of its life In this study, we estimate the kinetic energy deposition by massive stars in our Galaxy by considering the integrated Galactic initial mass function and modeling the stellar wind luminosity. The mass loss rate and terminal velocity of stellar winds during the main sequence, red supergiant, and Wolf-Rayet stages are estimated by adopting theoretical calculations and observational data published in the literature. We find that the total stellar wind luminosity by all massive stars in the Galaxy is about Lw ≈ 1.1×1041 ergs, which is about 1/4 of the power of supernova explosions, LSN ≈ 4.8×1041 ergs. If we assume that ˜1-1% of the wind luminosity could be converted to Galactic cosmic rays (GCRs) through collisonless shocks such as termination shocks in stellar bubbles and superbubbles, colliding-wind shocks in binaries, and bow-shocks of massive runaway stars, stellar winds are expected to make a significant contribution to GCR production, though lower than that of supernova remnants.

International Workshop on Linear Colliders 2010

CERN Multimedia

CERN. Geneva

2010-01-01

IWLC2010 International Workshop on Linear Colliders 2010ECFA-CLIC-ILC joint meeting: Monday 18 October - Friday 22 October 2010Venue: CERN and CICG (International Conference Centre Geneva, Switzerland) This year, the International Workshop on Linear Colliders organized by the European Committee for Future Accelerators (ECFA) will study the physics, detectors and accelerator complex of a linear collider covering both CLIC and ILC options.Contact Workshop Secretariat  IWLC2010 is hosted by CERN

Estimates of Fermilab Tevatron collider performance

International Nuclear Information System (INIS)

Dugan, G.

1991-09-01

This paper describes a model which has been used to estimate the average luminosity performance of the Tevatron collider. In the model, the average luminosity is related quantitatively to various performance parameters of the Fermilab Tevatron collider complex. The model is useful in allowing estimates to be developed for the improvements in average collider luminosity to be expected from changes in the fundamental performance parameters as a result of upgrades to various parts of the accelerator complex

Strings and superstrings. Electron linear colliders

International Nuclear Information System (INIS)

Alessandrini, V.; Bambade, P.; Binetruy, P.; Kounnas, C.; Le Duff, J.; Schwimmer, A.

1989-01-01

Basic string theory; strings in interaction; construction of strings and superstrings in arbitrary space-time dimensions; compactification and phenomenology; linear e+e- colliders; and the Stanford linear collider were discussed [fr

The standard model and colliders

International Nuclear Information System (INIS)

Hinchliffe, I.

1987-03-01

Some topics in the standard model of strong and electroweak interactions are discussed, as well as how these topics are relevant for the high energy colliders which will become operational in the next few years. The radiative corrections in the Glashow-Weinberg-Salam model are discussed, stressing how these corrections may be measured at LEP and the SLC. CP violation is discussed briefly, followed by a discussion of the Higgs boson and the searches which are relevant to hadron colliders are then discussed. Some of the problems which the standard model does not solve are discussed, and the energy ranges accessible to the new colliders are indicated

Hadron collider physics 2005. Proceedings

International Nuclear Information System (INIS)

Campanelli, M.; Clark, A.; Wu, X.

2006-01-01

The Hadron Collider Physics Symposia (HCP) are a new series of conferences that follow the merger of the Hadron Collider Conferences with the LHC Symposia series, with the goal of maximizing the shared experience of the Tevatron and LHC communities. This book gathers the proceedings of the first symposium, HCP2005, and reviews the state of the art in the key physics directions of experimental hadron collider research: - QCD physics - precision electroweak physics - c-, b-, and t-quark physics - physics beyond the Standard Model - heavy ion physics The present volume will serve as a reference for everyone working in the field of accelerator-based high-energy physics. (orig.)

Prospects for next-generation e+e- linear colliders

International Nuclear Information System (INIS)

Ruth, R.D.

1990-02-01

The purpose of this paper is to review progress in the US towards a next generation linear collider. During 1988, there were three workshops held on linear colliders: ''Physics of Linear Colliders,'' in Capri, Italy, June 14--18, 1988; Snowmass 88 (Linear Collider subsection) June 27--July 15, 1988; and SLAC International Workshop on Next Generation Linear Colliders, November 28--December 9, 1988. In this paper, I focus on reviewing the issues and progress on a next generation linear collider. The energy range is dictated by physics with a mass reach well beyond LEP, although somewhat short of SSC. The luminosity is that required to obtain 10 3 --10 4 units of R 0 per year. The length is consistent with a site on Stanford land with collision occurring on the SLAC site; the power was determined by economic considerations. Finally, the technology as limited by the desire to have a next generation linear collider by the next century. 37 refs., 3 figs., 6 tabs

Vanilla Technicolor at Linear Colliders

DEFF Research Database (Denmark)

T. Frandsen, Mads; Jarvinen, Matti; Sannino, Francesco

2011-01-01

We analyze the reach of Linear Colliders (LC)s for models of dynamical electroweak symmetry breaking. We show that LCs can efficiently test the compositeness scale, identified with the mass of the new spin-one resonances, till the maximum energy in the center-of-mass of the colliding leptons. In ...

CLIC e+e- Linear Collider Studies

CERN Document Server

Dannheim, Dominik; Linssen, Lucie; Schulte, Daniel; Simon, Frank; Stapnes, Steinar; Toge, Nobukazu; Weerts, Harry; Wells, James

2012-01-01

This document provides input from the CLIC e+e- linear collider studies to the update process of the European Strategy for Particle Physics. It is submitted on behalf of the CLIC/CTF3 collaboration and the CLIC physics and detector study. It describes the exploration of fundamental questions in particle physics at the energy frontier with a future TeV-scale e+e- linear collider based on the Compact Linear Collider (CLIC) two-beam acceleration technique. A high-luminosity high-energy e+e- collider allows for the exploration of Standard Model physics, such as precise measurements of the Higgs, top and gauge sectors, as well as for a multitude of searches for New Physics, either through direct discovery or indirectly, via high-precision observables. Given the current state of knowledge, following the observation of a \\sim125 GeV Higgs-like particle at the LHC, and pending further LHC results at 8 TeV and 14 TeV, a linear e+e- collider built and operated in centre-of-mass energy stages from a few-hundred GeV up t...

Performance Limitations in High-Energy Ion Colliders

CERN Document Server

Fischer, Wolfram

2005-01-01

High-energy ion colliders (hadron colliders operating with species other than protons) are premier research tools for nuclear physics. The collision energy and high luminosity are important design and operations considerations. However, the experiments also expect flexibility with frequent changes in the collision energy, lattice configuration, and ion species, including asymmetric collisions. For the creation, acceleration, and storage of bright intense ion beams, attention must be paid to space charge, charge exchange, and intra-beam scattering effects. The latter leads to luminosity lifetimes of only a few hours for heavy ions. Ultimately cooling at full energy is needed to overcome this effect. Currently, the Relativistic Heavy Ion Collider at BNL is the only operating high-energy ion collider. The Large Hadron Collider, under construction at CERN, will also run with heavy ions.

Corolla chirality does not contribute to directed pollen movement in Hypericum perforatum (Hypericaceae): mirror image pinwheel flowers function as radially symmetric flowers in pollination.

Science.gov (United States)

Diller, Carolina; Fenster, Charles B

2016-07-01

Corolla chirality, the pinwheel arrangement of petals within a flower, is found throughout the core eudicots. In 15 families, different chiral type flowers (i.e., right or left rotated corolla) exist on the same plant, and this condition is referred to as unfixed/enantiomorphic corolla chirality. There are no investigations on the significance of unfixed floral chirality on directed pollen movement even though analogous mirror image floral designs, for example, enantiostyly, has evolved in response to selection to direct pollinator and pollen movement. Here, we examine the role of corolla chirality on directing pollen transfer, pollinator behavior, and its potential influence on disassortative mating. We quantified pollen transfer and pollinator behavior and movement for both right and left rotated flowers in two populations of Hypericum perforatum. In addition, we quantified the number of right and left rotated flowers at the individual level. Pollinators were indifferent to corolla chirality resulting in no difference in pollen deposition between right and left flowers. Corolla chirality had no effect on pollinator and pollen movement between and within chiral morphs. Unlike other mirror image floral designs, corolla chirality appears to play no role in promoting disassortative mating in this species.

SLAC linear collider conceptual design report

Energy Technology Data Exchange (ETDEWEB)

1980-06-01

The linear collider system is described in detail, including the transport system, the collider lattice, final focusing system, positron production, beam damping and compression, high current electron source, instrumentation and control, and the beam luminosity. The experimental facilities and the experimental uses are discussed along with the construction schedule and estimated costs. Appendices include a discussion of space charge effects in the linear accelerator, emittance growth in the collider, the final focus system, beam-beam instabilities and pinch effects, and detector backgrounds. (GHT)

SLAC linear collider conceptual design report

International Nuclear Information System (INIS)

1980-06-01

The linear collider system is described in detail, including the transport system, the collider lattice, final focusing system, positron production, beam damping and compression, high current electron source, instrumentation and control, and the beam luminosity. The experimental facilities and the experimental uses are discussed along with the construction schedule and estimated costs. Appendices include a discussion of space charge effects in the linear accelerator, emittance growth in the collider, the final focus system, beam-beam instabilities and pinch effects, and detector backgrounds

Colliding druthers

International Nuclear Information System (INIS)

Ankenbrandt, C.; Johnson, R.P.

1977-01-01

Recommendations are made to maximize the usefulness of the colliding beam facility of the Main Ring and Energy Doubler at the Fermilab accelerator. The advantages of the transposed crossing geometry over the kissing geometry are pointed out

Test facilities for future linear colliders

International Nuclear Information System (INIS)

Ruth, R.D.

1995-12-01

During the past several years there has been a tremendous amount of progress on Linear Collider technology world wide. This research has led to the construction of the test facilities described in this report. Some of the facilities will be complete as early as the end of 1996, while others will be finishing up around the end 1997. Even now there are extensive tests ongoing for the enabling technologies for all of the test facilities. At the same time the Linear Collider designs are quite mature now and the SLC is providing the key experience base that can only come from a working collider. All this taken together indicates that the technology and accelerator physics will be ready for a future Linear Collider project to begin in the last half of the 1990s

Muon collider interaction region design

Directory of Open Access Journals (Sweden)

Y. I. Alexahin

2011-06-01

Full Text Available Design of a muon collider interaction region (IR presents a number of challenges arising from low β^{*}<1  cm, correspondingly large beta-function values and beam sizes at IR magnets, as well as the necessity to protect superconducting magnets and collider detectors from muon decay products. As a consequence, the designs of the IR optics, magnets and machine-detector interface are strongly interlaced and iterative. A consistent solution for the 1.5 TeV center-of-mass muon collider IR is presented. It can provide an average luminosity of 10^{34}  cm^{-2} s^{-1} with an adequate protection of magnet and detector components.

Lasers and future high energy colliders

International Nuclear Information System (INIS)

Parsa, Z.

1998-02-01

Future high energy colliders, directions for particle physics and relationship to new technology such as lasers are discussed. Experimental approaches to explore New Physics with emphasis on the utility of high energy colliders are also discussed

Physics at hadron colliders: Experimental view

International Nuclear Information System (INIS)

Siegrist, J.L.

1987-08-01

The physics of the hadron-hadron collider experiment is considered from an experimental point of view. The problems encountered in determination of how well the standard model describes collider results are discussed. 53 refs., 58 figs

Linear Colliders TESLA

International Nuclear Information System (INIS)

Anon.

1994-01-01

The aim of the TESLA (TeV Superconducting Linear Accelerator) collaboration (at present 19 institutions from seven countries) is to establish the technology for a high energy electron-positron linear collider using superconducting radiofrequency cavities to accelerate its beams. Another basic goal is to demonstrate that such a collider can meet its performance goals in a cost effective manner. For this the TESLA collaboration is preparing a 500 MeV superconducting linear test accelerator at the DESY Laboratory in Hamburg. This TTF (TESLA Test Facility) consists of four cryomodules, each approximately 12 m long and containing eight 9-cell solid niobium cavities operating at a frequency of 1.3 GHz

Linear colliders for photon collisions

International Nuclear Information System (INIS)

Anon.

1994-01-01

The enthusiasm of the first international workshop on photonphoton colliders and associated physics, held at the Lawrence Berkeley Laboratory from 28 March - 1 April, could have set a ball rolling. According to proponents of this physics, the particle physics one can study with a high energy linear collider is special and complements that of a hadron supercollider

Overview of colliding beam facilities

International Nuclear Information System (INIS)

Herrera, J.C.; Month, M.

1979-01-01

A review is presented of the colliding beam facilities in existence today. The major high energy physics facilities around the world are described, and a view is presented of the beam collisions in which the instruments used to make the beams collide and those used to detect the products of particle interactions in the beam overlap region are described

Beyond the Large Hadron Collider: A First Look at Cryogenics for CERN Future Circular Colliders

Science.gov (United States)

Lebrun, Philippe; Tavian, Laurent

Following the first experimental discoveries at the Large Hadron Collider (LHC) and the recent update of the European strategy in particle physics, CERN has undertaken an international study of possible future circular colliders beyond the LHC. The study, conducted with the collaborative participation of interested institutes world-wide, considers several options for very high energy hadron-hadron, electron-positron and hadron-electron colliders to be installed in a quasi-circular underground tunnel in the Geneva basin, with a circumference of 80 km to 100 km. All these machines would make intensive use of advanced superconducting devices, i.e. high-field bending and focusing magnets and/or accelerating RF cavities, thus requiring large helium cryogenic systems operating at 4.5 K or below. Based on preliminary sets of parameters and layouts for the particle colliders under study, we discuss the main challenges of their cryogenic systems and present first estimates of the cryogenic refrigeration capacities required, with emphasis on the qualitative and quantitative steps to be accomplished with respect to the present state-of-the-art.

Avian fatalities at wind energy facilities in North America: A comparison of recent approaches

Science.gov (United States)

Johnson, Douglas H.; Loss, Scott R.; Smallwood, K. Shawn; Erickson, Wallace P.

2016-01-01

Three recent publications have estimated the number of birds killed each year by wind energy facilities at 2012 build-out levels in the United States. The 3 publications differ in scope, methodology, and resulting estimates. We compare and contrast characteristics of the approaches used in the publications. In addition, we describe decisions made in obtaining the estimates that were produced. Despite variation in the 3 approaches, resulting estimates were reasonably similar; about a quarter- to a half-million birds are killed per year by colliding with wind turbines.

Superphysics at UNK collider

International Nuclear Information System (INIS)

Kereselidze, A.R.; Liparteliani, A.G.; Sokolov, A.A.; Volkov, G.G.

1988-01-01

The theoretical incompleteness of standard model and the way of going beyond frames on the basis of supersymmetry are considered. The most important directions of experimental researches at the colliders of a new generation are given. Theoretical estimates of masses of supersymmetrical particles in the framework of N=1 supergravity obtained from compactification of the popular E 8 xE 8 superstring theories are presented. The experimental search for supersymmetrical particles at the UNK pp-collider (√s=6 TeV) is performed

Final focus systems for linear colliders

International Nuclear Information System (INIS)

Erickson, R.A.

1987-11-01

The final focus system of a linear collider must perform two primary functions, it must focus the two opposing beams so that their transverse dimensions at the interaction point are small enough to yield acceptable luminosity, and it must steer the beams together to maintain collisions. In addition, the final focus system must transport the outgoing beams to a location where they can be recycled or safely dumped. Elementary optical considerations for linear collider final focus systems are discussed, followed by chromatic aberrations. The design of the final focus system of the SLAC Linear Collider (SLC) is described. Tuning and diagnostics and steering to collision are discussed. Most of the examples illustrating the concepts covered are drawn from the SLC, but the principles and conclusions are said to be generally applicable to other linear collider designs as well. 26 refs., 17 figs

Considerations on Energy Frontier Colliders after LHC

Energy Technology Data Exchange (ETDEWEB)

Shiltsev, Vladimir [Fermilab

2016-11-15

Since 1960’s, particle colliders have been in the forefront of particle physics, 29 total have been built and operated, 7 are in operation now. At present the near term US, European and international strategies of the particle physics community are centered on full exploitation of the physics potential of the Large Hadron Collider (LHC) through its high-luminosity upgrade (HL-LHC). The future of the world-wide HEP community critically depends on the feasibility of possible post-LHC colliders. The concept of the feasibility is complex and includes at least three factors: feasibility of energy, feasibility of luminosity and feasibility of cost. Here we overview all current options for post-LHC colliders from such perspective (ILC, CLIC, Muon Collider, plasma colliders, CEPC, FCC, HE-LHC) and discuss major challenges and accelerator R&D required to demonstrate feasibility of an energy frontier accelerator facility following the LHC. We conclude by taking a look into ultimate energy reach accelerators based on plasmas and crystals, and discussion on the perspectives for the far future of the accelerator-based particle physics. This paper largely follows previous study [1] and the presenta ion given at the ICHEP’2016 conference in Chicago [2].

Infrared Photometric Study of Wolf–Rayet Galaxies

Science.gov (United States)

Chen, P. S.; Yang, X. H.; Liu, J. Y.; Shan, H. G.

2018-01-01

We collected observational data on 781 Wolf–Rayet (WR) galaxies from the literature to photometrically study their infrared properties measured by the 2MASS, WISE, IRAS, AKARI, and Herschel missions. It is found that in the 1–5 μm range the radiations of WR galaxies are dominated by the free–free emissions from the stellar winds and the circumstellar dust from the late-type stars in the host galaxy. In the 5–22 μm range, the radiation of WR galaxies is dominated by the free–free emissions and the synchrotron radiation from the central active galactic nucleus (AGN; but not always present). In the 22–140 μm range, the radiations of WR galaxies are dominated by the free–free emissions and the star formation/starburst activities. In the 250–500 μm range, the radiation of WR galaxies is dominated by the free–free emissions. In addition, the comparison with the non-WR galaxies is made. It is shown that some star formation WR galaxies have redder near-infrared colors than non-WR star-forming galaxies probably due to the gas emission in the near-infrared. In the 2–5 μm region WR galaxies have redder colors due to the thermal emission from circumstellar dust of late-type stars and the enhanced gas emission. In the 5–22 μm region, both WR galaxies and non-WR galaxies have similar behavior, indicative of having similar free–free emission as the dominant radiation. In the 25–140 μm region, both types of galaxies also have similar behavior, indicative of having free–free emission from the stellar winds or the thermal radiation from the starburst/star formation as the dominant radiation.

STAR FORMATION IN TURBULENT MOLECULAR CLOUDS WITH COLLIDING FLOW

International Nuclear Information System (INIS)

Matsumoto, Tomoaki; Dobashi, Kazuhito; Shimoikura, Tomomi

2015-01-01

Using self-gravitational hydrodynamical numerical simulations, we investigated the evolution of high-density turbulent molecular clouds swept by a colliding flow. The interaction of shock waves due to turbulence produces networks of thin filamentary clouds with a sub-parsec width. The colliding flow accumulates the filamentary clouds into a sheet cloud and promotes active star formation for initially high-density clouds. Clouds with a colliding flow exhibit a finer filamentary network than clouds without a colliding flow. The probability distribution functions (PDFs) for the density and column density can be fitted by lognormal functions for clouds without colliding flow. When the initial turbulence is weak, the column density PDF has a power-law wing at high column densities. The colliding flow considerably deforms the PDF, such that the PDF exhibits a double peak. The stellar mass distributions reproduced here are consistent with the classical initial mass function with a power-law index of –1.35 when the initial clouds have a high density. The distribution of stellar velocities agrees with the gas velocity distribution, which can be fitted by Gaussian functions for clouds without colliding flow. For clouds with colliding flow, the velocity dispersion of gas tends to be larger than the stellar velocity dispersion. The signatures of colliding flows and turbulence appear in channel maps reconstructed from the simulation data. Clouds without colliding flow exhibit a cloud-scale velocity shear due to the turbulence. In contrast, clouds with colliding flow show a prominent anti-correlated distribution of thin filaments between the different velocity channels, suggesting collisions between the filamentary clouds

STAR FORMATION IN TURBULENT MOLECULAR CLOUDS WITH COLLIDING FLOW

Energy Technology Data Exchange (ETDEWEB)

Matsumoto, Tomoaki [Faculty of Humanity and Environment, Hosei University, Fujimi, Chiyoda-ku, Tokyo 102-8160 (Japan); Dobashi, Kazuhito; Shimoikura, Tomomi, E-mail: matsu@hosei.ac.jp [Department of Astronomy and Earth Sciences, Tokyo Gakugei University, Koganei, Tokyo 184-8501 (Japan)

2015-03-10

Using self-gravitational hydrodynamical numerical simulations, we investigated the evolution of high-density turbulent molecular clouds swept by a colliding flow. The interaction of shock waves due to turbulence produces networks of thin filamentary clouds with a sub-parsec width. The colliding flow accumulates the filamentary clouds into a sheet cloud and promotes active star formation for initially high-density clouds. Clouds with a colliding flow exhibit a finer filamentary network than clouds without a colliding flow. The probability distribution functions (PDFs) for the density and column density can be fitted by lognormal functions for clouds without colliding flow. When the initial turbulence is weak, the column density PDF has a power-law wing at high column densities. The colliding flow considerably deforms the PDF, such that the PDF exhibits a double peak. The stellar mass distributions reproduced here are consistent with the classical initial mass function with a power-law index of –1.35 when the initial clouds have a high density. The distribution of stellar velocities agrees with the gas velocity distribution, which can be fitted by Gaussian functions for clouds without colliding flow. For clouds with colliding flow, the velocity dispersion of gas tends to be larger than the stellar velocity dispersion. The signatures of colliding flows and turbulence appear in channel maps reconstructed from the simulation data. Clouds without colliding flow exhibit a cloud-scale velocity shear due to the turbulence. In contrast, clouds with colliding flow show a prominent anti-correlated distribution of thin filaments between the different velocity channels, suggesting collisions between the filamentary clouds.

Future prospects for electron colliders

CERN Document Server

Toge, N

2001-01-01

An overview on the future prospects for electron colliders is presented. In the first part of this paper we will walk through the status of current development of next-generation electron linear colliders of sub-TeV to TeV energy range. Then we will visit recent results from technological developments which aim at longer term future for higher energy accelerators.

Sextupole correction magnets for the Large Hadron Collider

CERN Document Server

Meinke, R B; Senti, M; Op de Beeck, W J; De Ryck, C; MacKay, W W

1999-01-01

About 2500 superconducting sextupole corrector magnets (MCS) are needed for the Large Hadron Collider (LHC) at CERN to compensate persistent current sextupole fields of the main dipoles. The MCS is a cold bore magnet with iron yoke. The coils are made from a NbTi conductor, which is cooled to 1.9 K. In the original CERN design 6 individual sub-coils, made from a monolithic composite conductor, are assembled and spliced together to form the sextupole. The coils are individually wound around precision-machined central islands and stabilized with matching saddle pieces at both ends. The Advanced Magnet Lab, Inc. (AML) has produced an alternative design, which gives improved performance and reliability at reduced manufacturing cost. In the AML design, the magnet consists of three splice-free sub-coils, which are placed with an automated winding process into pockets of prefabricated G-11 support cylinders. Any assembly process of sub-coils with potential misalignment is eliminated. The AML magnet uses a Kapton-wra...

The International Linear Collider Progress Report 2015

Energy Technology Data Exchange (ETDEWEB)

Evans, L. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Yamamoto, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

2015-07-15

The International Committee for Future Accelerators (ICFA) set up the Global Design Effort (GDE) for the design of the International Linear Collider (ILC) in 2005. Drawing on the resources of over 300 national laboratories, universities and institutes worldwide, the GDE produced a Reference Design Report in 2007, followed by a more detailed Technical Design Report (TDR) in 2013. Following this report, the GDE was disbanded. A compact core team, the Linear Collider Collaboration (LCC), replaced it. This is still under the auspices of ICFA and is directly overseen by the Linear Collider Board, which reports to ICFA. The LCC is charged with continuing the design effort on a much-reduced scale until the Project is approved for construction. An additional mandate of the LCC was to bring together all linear collider work, including the CERN-based Compact Linear Collider (CLIC) under one structure in order to exploit synergies between the two studies.

Status of the SLAC Linear Collider Project

International Nuclear Information System (INIS)

Stiening, R.

1983-01-01

The SLAC Linear Collider Project has two principal goals. The first is to serve as a prototype for a future very high energy linear electron-positron collider. The second is to quickly, at low cost, achieve sufficient luminosity at 100 GeV center-of-mass energy to explore the physics of the Z 0 . The first goal is important to the future of electron-positron physics because the rapid increase of synchrotron radiation with energy causes the cost of circular storage ring colliders to whereas the cost of linear colliders increases only in proportion to the center-of-mass energy. The second is important because the existance at SLAC of a linear accelerator which can be converted at low cost to collider operation makes possible a unique opportunity to quickly achieve 100 GeV center-of-mass collisions. At the design luminosity of 6.0 x 10 30 many thousands of Z 0 decays should be observed in each day of operation

Searching for WR stars in I Zw 18 -- The origin of HeII emission

OpenAIRE

de Mello, Duilia; Schaerer, Daniel; Heldmann, Jennifer; Leitherer, Claus

1998-01-01

I Zw 18 is the most metal poor star-forming galaxy known and is an ideal laboratory to probe stellar evolution theory at low metallicities. Using archival HST WFPC2 imaging and FOS spectroscopy we were able to improve previous studies. We constructed a continuum free HeII map, which was used to identify Wolf-Rayet (WR) stars recently found by ground-based spectroscopy and to locate diffuse nebular emission. Most of the HeII emission is associated with the NW stellar cluster, clearly displaced...

Magnet R and D for future colliders

International Nuclear Information System (INIS)

Sabbi, Gian Luca

2001-01-01

High-energy colliders complementing and expanding the physics reach of LHC are presently under study in the United States, Europe and Japan. The magnet system is a major cost driver for hadron colliders at the energy frontier, and critical to the successful operation of muon colliders. Under most scenarios, magnet design as well as vacuum and cryogenic systems are complicated by high radiation loads. Magnet R and D programs are underway worldwide to take advantage of new developments in superconducting materials, achieve higher efficiency and simplify fabrication while preserving accelerator-class field quality. A review of recent progress in magnet technology for future colliders is presented, with emphasis on the most innovative design concepts and fabrication techniques

Parameters of the SLAC Next Linear Collider

International Nuclear Information System (INIS)

Raubenheimer, T.; Adolphsen, C.; Burke, D.

1995-05-01

In this paper, the authors present the parameters and layout of the Next Linear Collider (NLC). The NLC is the SLAC design of a future linear collider using X-band RF technology in the main linacs. The collider would have an initial center-of-mass energy of 0.5 TeV which would be upgraded to 1 TeV and then 1.5 TeV in two stages. The design luminosity is > 5 x 10 33 cm -2 sec -1 at 0.5 TeV and > 10 34 cm -2 sec -1 at 1.0 and 1.5 TeV. They briefly describe the components of the collider and the proposed energy upgrade scenario

RHIC spin: The first polarized proton collider

International Nuclear Information System (INIS)

Roser, T.

1994-01-01

The very successful program of QCD and electroweak tests at the high energy hadron colliders have shown that the perturbative QCD has progressed towards becoming a ''precision'' theory. At the same time, it has been shown that with the help of Siberian Snakes it is feasible to accelerate polarized protons to high enough energies where the proven methods of collider physics can be used to probe the spin content of the proton but also where fundamental tests of the spin effects in the standard model are possible. With Siberian Snakes the Relativistic Heavy Ion Collider (RHIC) will be the first collider to allow for 250 GeV on 250 GeV polarized proton collisions

Proton-Proton and Proton-Antiproton Colliders

CERN Document Server

Scandale, Walter

2014-01-01

In the last five decades, proton–proton and proton–antiproton colliders have been the most powerful tools for high energy physics investigations. They have also deeply catalyzed innovation in accelerator physics and technology. Among the large number of proposed colliders, only four have really succeeded in becoming operational: the ISR, the SppbarS, the Tevatron and the LHC. Another hadron collider, RHIC, originally conceived for ion–ion collisions, has also been operated part-time with polarized protons. Although a vast literature documenting them is available, this paper is intended to provide a quick synthesis of their main features and key performance.

Dedicating Fermilab's Collider

International Nuclear Information System (INIS)

Anon.

1986-01-01

It was a bold move to have a fullscale dedication ceremony for the new proton-antiproton Collider at the Fermilab Tevatron on 13 October, two days before the first collisions were seen. However the particles dutifully behaved as required, and over the following weekend the Collider delivered its goods at a total energy of 1600 GeV, significantly boosting the world record for laboratory collisions

The radioprotector WR-2721 reduces neutron-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in mouse splenocytes when administered prior to or following irradiation

International Nuclear Information System (INIS)

Grdina, D.J.; Basic, I.

1992-01-01

An in vitro T-lymphocyte cloning technique has been applied to study the effects of JANUS fission-spectrum neutron irradiation and the radioprotector S-2-(3-aminopropylamino) ethylphosphorothioic acid (WR-2721) on the subsequent development of somatic mutations at the hypoxanthine-guanine phosphoribosyl transferase (hprt) locus in hybrid B6CF1 male mice. In control studies performed to establish an in vitro cloning technique, the mutant frequencies of splenic T-lymphocytes, as a result of exposure to a 100 cGy dose of neutrons, increased with time from a control level of 9 x 10 -7 to a maximum value of 1.7 x 10 -5 at 56 days following irradiation. Between 56 and 150 days after irradiation, mutant frequencies were observed to plateau and remain stable. All subsequent determinations were performed at 56 days following the experimental treatment of animals. WR-2721 at a dose of 400 mg/kg was effective in protecting against the induction of hprt mutants (i.e. a mutant frequency reduction factor, MFRF) following the largest dose of neutrons used (i.e. 150 cGy). The antimutagenic effectiveness of WR-2721 administered 30 min prior to irradiation was unaffected, even when the dose was reduced to 200 mg/kg. These findings confirm our earlier report using the radioprotector N-(2-mercaptoethyl)-1,2-diaminopropane (WR-1065) under in vitro conditions, and demonstrate that these agents can be used as effective antimutagens even when they are administered up to 3 h following radiation exposure. (Author)

The Colliding Beams Sequencer

International Nuclear Information System (INIS)

Johnson, D.E.; Johnson, R.P.

1989-01-01

The Colliding Beam Sequencer (CBS) is a computer program used to operate the pbar-p Collider by synchronizing the applications programs and simulating the activities of the accelerator operators during filling and storage. The Sequencer acts as a meta-program, running otherwise stand alone applications programs, to do the set-up, beam transfers, acceleration, low beta turn on, and diagnostics for the transfers and storage. The Sequencer and its operational performance will be described along with its special features which include a periodic scheduler and command logger. 14 refs., 3 figs

Particle physics experiments at high energy colliders

International Nuclear Information System (INIS)

Hauptman, John

2011-01-01

Written by one of the detector developers for the International Linear Collider, this is the first textbook for graduate students dedicated to the complexities and the simplicities of high energy collider detectors. It is intended as a specialized reference for a standard course in particle physics, and as a principal text for a special topics course focused on large collider experiments. Equally useful as a general guide for physicists designing big detectors. (orig.)

Patterns of migrating soaring migrants indicate attraction to marine wind farms.

Science.gov (United States)

Skov, Henrik; Desholm, Mark; Heinänen, Stefan; Kahlert, Johnny A; Laubek, Bjarke; Jensen, Niels Einar; Žydelis, Ramūnas; Jensen, Bo Præstegaard

2016-12-01

Monitoring of bird migration at marine wind farms has a short history, and unsurprisingly most studies have focused on the potential for collisions. Risk for population impacts may exist to soaring migrants such as raptors with K-strategic life-history characteristics. Soaring migrants display strong dependence on thermals and updrafts and an affinity to land areas and islands during their migration, a behaviour that creates corridors where raptors move across narrow straits and sounds and are attracted to islands. Several migration corridors for soaring birds overlap with the development regions for marine wind farms in NW Europe. However, no empirical data have yet been available on avoidance or attraction rates and behavioural reactions of soaring migrants to marine wind farms. Based on a post-construction monitoring study, we show that all raptor species displayed a significant attraction behaviour towards a wind farm. The modified migratory behaviour was also significantly different from the behaviour at nearby reference sites. The attraction was inversely related to distance to the wind farm and was primarily recorded during periods of adverse wind conditions. The attraction behaviour suggests that migrating raptor species are far more at risk of colliding with wind turbines at sea than hitherto assessed. © 2016 The Author(s).

Status of the Future Circular Collider Study

Science.gov (United States)

Benedikt, Michael

2016-03-01

Following the 2013 update of the European Strategy for Particle Physics, the international Future Circular Collider (FCC) Study has been launched by CERN as host institute, to design an energy frontier hadron collider (FCC-hh) in a new 80-100 km tunnel with a centre-of-mass energy of about 100 TeV, an order of magnitude beyond the LHC's, as a long-term goal. The FCC study also includes the design of a 90-350 GeV high-luminosity lepton collider (FCC-ee) installed in the same tunnel, serving as Higgs, top and Z factory, as a potential intermediate step, as well as an electron-proton collider option (FCC-he). The physics cases for such machines will be assessed and concepts for experiments will be developed in time for the next update of the European Strategy for Particle Physics by the end of 2018. The presentation will summarize the status of machine designs and parameters and discuss the essential technical components to be developed in the frame of the FCC study. Key elements are superconducting accelerator-dipole magnets with a field of 16 T for the hadron collider and high-power, high-efficiency RF systems for the lepton collider. In addition the unprecedented beam power presents special challenges for the hadron collider for all aspects of beam handling and machine protection. First conclusions of geological investigations and implementation studies will be presented. The status of the FCC collaboration and the further planning for the study will be outlined.

Use of wind energy

Energy Technology Data Exchange (ETDEWEB)

Vasil' yeva, I G

1982-01-01

Programs on the use of wind energy have been adopted in over 12 countries. The WU of low power is manufactured by over 100 firms. One of the main trends for the use of wind energy currently is water pumping. The cost of operating water pumps with diesel and electric drive has increased and they have become not very accessible for a considerable part of the population in the developing countries. There are now about one million wind pump units (WPU) operating in the world, mainly in the United States, Australia and Argentina. The average power of the WPU is less than or equal to 0.5 kW. A trend is developing wind energy associated with the creation of wind heat units for heat supply of houses. When powerful experimental WEU are operating, the problem was revealed of their influence on the environment. The main difficulties are associated with creating WEU of electromagnetic interference, which in particular, influence the quality of television transmissions. This problem was encountered in operating the WEU P = 200 kW in the United States in Rhode Island. Normal operation of the television receivers was guaranteed with the help of cable network. A method was developed from calculating the zone of interferences which should be used in the future in setting up the WEU. A study was made of the noise from the operating of the WEU. The noise level of the WEU is in limits of permissible, however in direct proximity to the unit, intensive infrasonic fluctuations develop. The most important ecological consequence of building powerful WEU could be the death of nocturnal birds as a result of their colliding with the rotating blades. It is noted that this can be avoided by lighting the WEU.

Challenges for highest energy circular colliders

CERN Document Server

Benedikt, M; Wenninger, J; Zimmermann, F

2014-01-01

A new tunnel of 80–100 km circumference could host a 100 TeV centre-of-mass energy-frontier proton collider (FCC-hh/VHE-LHC), with a circular lepton collider (FCCee/TLEP) as potential intermediate step, and a leptonhadron collider (FCC-he) as additional option. FCC-ee, operating at four different energies for precision physics of the Z, W, and Higgs boson and the top quark, represents a significant push in terms of technology and design parameters. Pertinent R&D efforts include the RF system, topup injection scheme, optics design for arcs and final focus, effects of beamstrahlung, beam polarization, energy calibration, and power consumption. FCC-hh faces other challenges, such as high-field magnet design, machine protection and effective handling of large synchrotron radiation power in a superconducting machine. All these issues are being addressed by a global FCC collaboration. A parallel design study in China prepares for a similar, but smaller collider, called CepC/SppC.

Super High Energy Colliding Beam Accelerators

International Nuclear Information System (INIS)

Abdelaziz, M.E.

2009-01-01

This lecture presents a review of cyclic accelerators and their energy limitations. A description is given of the phase stability principle and evolution of the synchrotron, an accelerator without energy limitation. Then the concept of colliding beams emerged to yield doubling of the beam energy as in the Tevatron 2 trillion electron volts (TeV) proton collider at Fermilab and the Large Hadron Collider (LHC) which is now planned as a 14-TeV machine in the 27 kilometer tunnel of the Large Electron Positron (LEP) collider at CERN. Then presentation is given of the Superconducting Supercollider (SSC), a giant accelerator complex with energy 40-TeV in a tunnel 87 kilometers in circumference under the country surrounding Waxahachie in Texas, U.S.A. These superhigh energy accelerators are intended to smash protons against protons at energy sufficient to reveal the nature of matter and to consolidate the prevailing general theory of elementary particle.

An Afterburner at the ILC: The Collider Viewpoint

International Nuclear Information System (INIS)

Raubenheimer, T

2004-01-01

The concept of a high-gradient plasma wakefield accelerator is considered as an upgrade path for the International Linear Collider, a future linear collider. Basic parameters are presented based on those developed for the SLC ''Afterburner.'' Basic layout considerations are described and the primary concerns related to the collider operation are discussed

Radioprotection by WR-151327 against the late normal tissue damage in mouse hind legs from gamma ray radiation

International Nuclear Information System (INIS)

Matsushita, Satoru; Ando, Koichi; Koike, Sachiko

1994-01-01

To evaluate the protective effect of WR-151327 on late radiation-induced damaged to normal tissues in mice, the right hind legs of mice with or without WR-151327 administration (400 mg/kg) were irradiated with 137 Cs gamma rays. Leg contracture and skin shrinkage assays were performed at 380 days after irradiation. The mice were killed on day 400 postirradiation and histological sections of the legs were made. The thickness of the dermis, epidermis, and skin (dermis plus epidermis) was measured. The muscular area of the legs and the posterior knee angle between the femur and tibia were also measured. The left hind legs were similarly assessed as nonirradiated controls. Group means and standard deviations were calculated and dose-response curves were drawn for every endpoint. Then, the dose modifying factor (DMF) for each endpoint and the correlations among endpoints were determined. Latae damage assayed by leg contracture and skin shrinkage progressed with increasing radiation dose. However, it was reduced by drug treatment. The significant effect was indicated for skin shrinkage by a DMF of 1.8 at 35%. The DMF for leg contracture was 1.3 at 6 mm. In the irradiated legs, epidermal hyperplasia and dermal fibrosis in the skin, muscular atrophy, and extension disturbance of the knee joint were observed. These changes progressed with increasing radiation dose. Skin damage assayed by the present endpoints was also reduced by drug treatment by DMFs of 1.4 to 1.7. However, DMFs for damage to the muscle and knee were not determined because no isoeffect was observed. There were good correlations between leg contracture or skin shrinkage and the other endpoints in both untreated and drug-treated mice. WR-151327 has the potential to protect against radiation-induced late normal tissue damage. 17 refs., 6 figs., 2 tabs

Tau physics at p bar p colliders

International Nuclear Information System (INIS)

Konigsberg, J.

1993-01-01

Tau detection techniques in hadron colliders are discussed together with the measurements and searches performed so far. We also underline the importance tau physics has in present and future collider experiments

World lays groundwork for future linear collider

CERN Multimedia

Feder, Toni

2010-01-01

"New physics from the Large Hadron Collider can best be explored with a large lepton collider; realizing one will require mobilizing accelerator and particle physicists, funding agencies, and politicians" (3 pages)

Crystal Ball: On the Future High Energy Colliders

Energy Technology Data Exchange (ETDEWEB)

Shiltsev, Vladimir [Fermilab

2015-09-20

High energy particle colliders have been in the forefront of particle physics for more than three decades. At present the near term US, European and international strategies of the particle physics community are centered on full exploitation of the physics potential of the Large Hadron Collider (LHC) through its high-luminosity upgrade (HL-LHC). A number of next generation collider facilities have been proposed and are currently under consideration for the medium- and far-future of the accelerator-based high energy physics. In this paper we offer a uniform approach to evaluation of various accelerators based on the feasibility of their energy reach, performance reach and cost range. We briefly review such post-LHC options as linear e+e- colliders in Japan (ILC) or at CERN (CLIC), muon collider, and circular lepton or hadron colliders in China (CepC/SppC) and Europe (FCC). We conclude with a look into ultimate energy reach accelerators based on plasmas and crystals, and some perspectives for the far future of accelerator-based particle physics.

Beam-strahlung effects in e-p collider

International Nuclear Information System (INIS)

Cho, Y.

1982-09-01

The electromagnetic fields produced by one beam in an interaction point of a colliding-beam facility cause to the emission of synchrotron radiation by the other beam. This effect, the beam strahlung, for the e+e - colliders has been considered by several authors, and they have pointed out that the effect is very important consideration at very-high-energy e+e - colliders. At the first glance, the beam-strahlung effect can play an important role in the e-p collision due to the fact that the circulating currents in the collider are much higher than those of the e+e - machine. However the detailed study shows that is not the case because of the collision geometry involved. What follows in this note is the beam-strahlung derivations using the method previously used by Hofmann and Keil. The difference between this note and that of Hofman and Keil is that in the case of e+e - collider, equal mass particles are involved in the consideration and, in the e-p case, the electrons radiate and the protons provide the electromagnetic fields

Habitat use of bats in relation to wind turbines revealed by GPS tracking

Science.gov (United States)

Roeleke, Manuel; Blohm, Torsten; Kramer-Schadt, Stephanie; Yovel, Yossi; Voigt, Christian C.

2016-07-01

Worldwide, many countries aim at countering global climate change by promoting renewable energy. Yet, recent studies highlight that so-called green energy, such as wind energy, may come at environmental costs, for example when wind turbines kill birds and bats. Using miniaturized GPS loggers, we studied how an open-space foraging bat with high collision risk with wind turbines, the common noctule Nyctalus noctula (Schreber, 1774), interacts with wind turbines. We compared actual flight trajectories to correlated random walks to identify habitat variables explaining the movements of bats. Both sexes preferred wetlands but used conventionally managed cropland less than expected based on availability. During midsummer, females traversed the land on relatively long flight paths and repeatedly came close to wind turbines. Their flight heights above ground suggested a high risk of colliding with wind turbines. In contrast, males recorded in early summer commuted straight between roosts and foraging areas and overall flew lower than the operating range of most turbine blades, suggesting a lower collision risk. Flight heights of bats suggest that during summer the risk of collision with wind turbines was high for most studied bats at the majority of currently installed wind turbines. For siting of wind parks, preferred bat habitats and commuting routes should be identified and avoided.

Future colliders

International Nuclear Information System (INIS)

Palmer, R.B.; Gallardo, J.C.

1996-10-01

The high energy physics advantages, disadvantages and luminosity requirements of hadron (pp, pp), of lepton (e + e - , μ + μ - ) and photon-photon colliders are considered. Technical arguments for increased energy in each type of machine are presented. Their relative size, and the implications of size on cost are discussed

On the Future High Energy Colliders

Energy Technology Data Exchange (ETDEWEB)

Shiltsev, Vladimir [Fermilab

2015-09-28

High energy particle colliders have been in the forefront of particle physics for more than three decades. At present the near term US, European and international strategies of the particle physics community are centered on full exploitation of the physics potential of the Large Hadron Collider (LHC) through its high-luminosity upgrade (HL-LHC). A number of the next generation collider facilities have been proposed and are currently under consideration for the medium and far-future of accelerator-based high energy physics. In this paper we offer a uniform approach to evaluation of various accelerators based on the feasibility of their energy reach, performance potential and cost range.

Polarized electron sources for linear colliders

International Nuclear Information System (INIS)

Clendenin, J.E.; Ecklund, S.D.; Miller, R.H.; Schultz, D.C.; Sheppard, J.C.

1992-07-01

Linear colliders require high peak current beams with low duty factors. Several methods to produce polarized e - beams for accelerators have been developed. The SLC, the first linear collider, utilizes a photocathode gun with a GaAs cathode. Although photocathode sources are probably the only practical alternative for the next generation of linear colliders, several problems remain to be solved, including high voltage breakdown which poisons the cathode, charge limitations that are associated with the condition of the semiconductor cathode, and a relatively low polarization of ≤5O%. Methods to solve or at least greatly reduce the impact of each of these problems are at hand

Standard model Higgs physics at colliders

International Nuclear Information System (INIS)

Rosca, A.

2007-01-01

In this report we briefly review the experimental status and prospects to verify the Higgs mechanism of spontaneous symmetry breaking. The focus is on the most relevant aspects of the phenomenology of the Standard Model Higgs boson at current (Tevatron) and future (Large Hadron Collider, LHC and International Linear Collider, ILC) particle colliders. We review the Standard Model searches: searches at the Tevatron, the program planned at the LHC and prospects at the ILC. Emphasis is put on what follows after a candidate discovery at the LHC: the various measurements which are necessary to precisely determine what the properties of this Higgs candidate are. (author)

Physics at high luminosity muon colliders and a facility overview

International Nuclear Information System (INIS)

Parsa, Z.

2001-01-01

Physics potentials at future colliders including high luminosity μ + μ - colliders are discussed. Luminosity requirement, estimates for Muon collider energies of interest (0.1 TeV to 100 TeV) are calculated. Schematics and an overview of Muon Collider facility concept are also included

Overview of a high luminosity μ+μ- collider

International Nuclear Information System (INIS)

Palmer, R.B.; Gallardo, J.C.

1997-03-01

Muon Colliders have unique technical and physics advantages and disadvantages when compared with both hadron and electron machines. They should be regarded as complementary. Parameters are given of a 4 TeV high luminosity μ + μ - collider, and of a 0.5 TeV lower luminosity demonstration machine. The authors discuss the various systems in such muon colliders

Feedback Systems for Linear Colliders

International Nuclear Information System (INIS)

1999-01-01

Feedback systems are essential for stable operation of a linear collider, providing a cost-effective method for relaxing tight tolerances. In the Stanford Linear Collider (SLC), feedback controls beam parameters such as trajectory, energy, and intensity throughout the accelerator. A novel dithering optimization system which adjusts final focus parameters to maximize luminosity contributed to achieving record performance in the 1997-98 run. Performance limitations of the steering feedback have been investigated, and improvements have been made. For the Next Linear Collider (NLC), extensive feedback systems are planned as an integral part of the design. Feedback requirements for JLC (the Japanese Linear Collider) are essentially identical to NLC; some of the TESLA requirements are similar but there are significant differences. For NLC, algorithms which incorporate improvements upon the SLC implementation are being prototyped. Specialized systems for the damping rings, rf and interaction point will operate at high bandwidth and fast response. To correct for the motion of individual bunches within a train, both feedforward and feedback systems are planned. SLC experience has shown that feedback systems are an invaluable operational tool for decoupling systems, allowing precision tuning, and providing pulse-to-pulse diagnostics. Feedback systems for the NLC will incorporate the key SLC features and the benefits of advancing technologies

Linear collider systems and costs

International Nuclear Information System (INIS)

Loew, G.A.

1993-05-01

The purpose of this paper is to examine some of the systems and sub-systems involved in so-called ''conventional'' e + e - linear colliders and to study how their design affects the overall cost of these machines. There are presently a total of at least six 500 GeV c. of m. linear collider projects under study in the world. Aside from TESLA (superconducting linac at 1.3 GHz) and CLIC (two-beam accelerator with main linac at 30GHz), the other four proposed e + e - linear colliders can be considered ''conventional'' in that their main linacs use the proven technique of driving room temperature accelerator sections with pulsed klystrons and modulators. The centrally distinguishing feature between these projects is their main linac rf frequency: 3 GHz for the DESY machine, 11.424 GHz for the SLAC and JLC machines, and 14 GHz for the VLEPP machine. The other systems, namely the electron and positron sources, preaccelerators, compressors, damping rings and final foci, are fairly similar from project to project. Probably more than 80% of the cost of these linear colliders will be incurred in the two main linacs facing each other and it is therefore in their design and construction that major savings or extra costs may be found

Muon Collider Progress: Accelerators

Energy Technology Data Exchange (ETDEWEB)

Zisman, Michael S.

2011-09-10

A muon collider would be a powerful tool for exploring the energy-frontier with leptons, and would complement the studies now under way at the LHC. Such a device would offer several important benefits. Muons, like electrons, are point particles so the full center-of-mass energy is available for particle production. Moreover, on account of their higher mass, muons give rise to very little synchrotron radiation and produce very little beamstrahlung. The first feature permits the use of a circular collider that can make efficient use of the expensive rf system and whose footprint is compatible with an existing laboratory site. The second feature leads to a relatively narrow energy spread at the collision point. Designing an accelerator complex for a muon collider is a challenging task. Firstly, the muons are produced as a tertiary beam, so a high-power proton beam and a target that can withstand it are needed to provide the required luminosity of ~1 × 10{sup 34} cm{sup –2}s{sup –1}. Secondly, the beam is initially produced with a large 6D phase space, which necessitates a scheme for reducing the muon beam emittance (“cooling”). Finally, the muon has a short lifetime so all beam manipulations must be done very rapidly. The Muon Accelerator Program, led by Fermilab and including a number of U.S. national laboratories and universities, has undertaken design and R&D activities aimed toward the eventual construction of a muon collider. Design features of such a facility and the supporting R&D program are described.

Kinematics and resolution at future ep colliders

International Nuclear Information System (INIS)

Bluemlein, J.; Klein, M.

1992-01-01

Limitations due to resolution and kinematics are discussed of the (Q 2 , x) range accessible with electron-proton colliders after HERA. For the time after HERA one may think of two electron-proton colliders: an asymmetric energy machine and a rather symmetric one. Both colliders are compared here in order to study the influence of the different E l /E p ratios on the accessible kinematic range which is restricted due to angular coverage, finite detector resolution and calibration uncertainties

Polarized Electrons for Linear Colliders

International Nuclear Information System (INIS)

Clendenin, J.

2004-01-01

Future electron-positron linear colliders require a highly polarized electron beam with a pulse structure that depends primarily on whether the acceleration utilizes warm or superconducting rf structures. The International Linear Collider (ILC) will use cold structures for the main linac. It is shown that a dc-biased polarized photoelectron source such as successfully used for the SLC can meet the charge requirements for the ILC micropulse with a polarization approaching 90%

Photon Collider Physics with Real Photon Beams

International Nuclear Information System (INIS)

Gronberg, J; Asztalos, S

2005-01-01

Photon-photon interactions have been an important probe into fundamental particle physics. Until recently, the only way to produce photon-photon collisions was parasitically in the collision of charged particles. Recent advances in short-pulse laser technology have made it possible to consider producing high intensity, tightly focused beams of real photons through Compton scattering. A linear e + e - collider could thus be transformed into a photon-photon collider with the addition of high power lasers. In this paper they show that it is possible to make a competitive photon-photon collider experiment using the currently mothballed Stanford Linear Collider. This would produce photon-photon collisions in the GeV energy range which would allow the discovery and study of exotic heavy mesons with spin states of zero and two

Polarization Effects at a Muon Collider

International Nuclear Information System (INIS)

Parsa, Z.

1998-01-01

For Muon Colliders, Polarization will be a useful tool if high polarization is achievable with little luminosity loss. Formulation and effects of beam polarization and luminosity including polarization effects in Higgs resonance studies are discussed for improving precision measurements and Higgs resonance ''discovery'' capability e.g. at the First Muon Collider (FMC)

Summary of exotic collider concepts group

International Nuclear Information System (INIS)

Pellegrini, C.

1995-01-01

We present a summary of the discussions in the Exotic Collider Concepts Group. Most of the discussions were centered around the status and open problems for muon-muon and gamma-gamma colliders. In addition the group discussed some general problems and new results of accelerator physics. copyright 1995 American Institute of Physics

International linear collider reference design report

Energy Technology Data Exchange (ETDEWEB)

Aarons, G.

2007-06-22

The International Linear Collider will give physicists a new cosmic doorway to explore energy regimes beyond the reach of today's accelerators. A proposed electron-positron collider, the ILC will complement the Large Hadron Collider, a proton-proton collider at the European Center for Nuclear Research (CERN) in Geneva, Switzerland, together unlocking some of the deepest mysteries in the universe. With LHC discoveries pointing the way, the ILC -- a true precision machine -- will provide the missing pieces of the puzzle. Consisting of two linear accelerators that face each other, the ILC will hurl some 10 billion electrons and their anti-particles, positrons, toward each other at nearly the speed of light. Superconducting accelerator cavities operating at temperatures near absolute zero give the particles more and more energy until they smash in a blazing crossfire at the centre of the machine. Stretching approximately 35 kilometres in length, the beams collide 14,000 times every second at extremely high energies -- 500 billion-electron-volts (GeV). Each spectacular collision creates an array of new particles that could answer some of the most fundamental questions of all time. The current baseline design allows for an upgrade to a 50-kilometre, 1 trillion-electron-volt (TeV) machine during the second stage of the project. This reference design provides the first detailed technical snapshot of the proposed future electron-positron collider, defining in detail the technical parameters and components that make up each section of the 31-kilometer long accelerator. The report will guide the development of the worldwide R&D program, motivate international industrial studies and serve as the basis for the final engineering design needed to make an official project proposal later this decade.

Possible limits of plasma linear colliders

Science.gov (United States)

Zimmermann, F.

2017-07-01

Plasma linear colliders have been proposed as next or next-next generation energy-frontier machines for high-energy physics. I investigate possible fundamental limits on energy and luminosity of such type of colliders, considering acceleration, multiple scattering off plasma ions, intrabeam scattering, bremsstrahlung, and betatron radiation. The question of energy efficiency is also addressed.

Polarized proton colliders

International Nuclear Information System (INIS)

Roser, T.

1995-01-01

High energy polarized beam collisions will open up the unique physics opportunities of studying spin effects in hard processes. This will allow the study of the spin structure of the proton and also the verification of the many well documented expectations of spin effects in perturbative QCD and parity violation in W and Z production. Proposals for polarized proton acceleration for several high energy colliders have been developed. A partial Siberian Snake in the AGS has recently been successfully tested and full Siberian Snakes, spin rotators, and polarimeters for RHIC are being developed to make the acceleration of polarized beams to 250 GeV possible. This allows for the unique possibility of colliding two 250 GeV polarized proton beams at luminosities of up to 2 x 10 32 cm -2 s -1

Druid, displaying root module used for linear collider detectors

International Nuclear Information System (INIS)

Ruan, M

2012-01-01

Based on the ROOT TEve/TGeo classes and the standard linear collider data structure, a dedicated linear collider event display has been developed. It supports the latest detector models for both International Linear Collider and Compact Linear Collider as well as the CALICE test beam prototypes. It can be used to visualise event information at the generation, simulation and reconstruction levels. Many options are provided in an intuitive interface. It has been heavily employed in a variety of analyses.

Collider Physics

Indian Academy of Sciences (India)

This is summary of the activities of the working group on collider physics in the IXth Workshop on High Energy Physics Phenomenology (WHEPP-9) held at the Institute of Physics, Bhubaneswar, India in January 2006. Some of the work subsequently done on these problems by the subgroups formed during the workshop is ...

Muon colliders, frictional cooling and universal extra dimensions

Energy Technology Data Exchange (ETDEWEB)

Greenwald, Daniel E.

2011-07-20

A muon collider combines the advantages of proton-proton and electron-positron colliders, sidestepping many of their disadvantages, and has the potential to make discoveries and precision measurements at high energies. However, muons bring their own technical challenges, largely relating to their instability. We present a summary of the motivations and R and D efforts for a muon collider. We detail a scheme for preparing high-luminosity muon beams on timescales shorter than the muon lifetime, and an experiment to demonstrate aspects of this scheme at the Max Planck Institute for Physics. We also investigate the potentials to discover physics beyond the standard model at a muon collider. (orig.)

Muon colliders, frictional cooling and universal extra dimensions

International Nuclear Information System (INIS)

Greenwald, Daniel E.

2011-01-01

A muon collider combines the advantages of proton-proton and electron-positron colliders, sidestepping many of their disadvantages, and has the potential to make discoveries and precision measurements at high energies. However, muons bring their own technical challenges, largely relating to their instability. We present a summary of the motivations and R and D efforts for a muon collider. We detail a scheme for preparing high-luminosity muon beams on timescales shorter than the muon lifetime, and an experiment to demonstrate aspects of this scheme at the Max Planck Institute for Physics. We also investigate the potentials to discover physics beyond the standard model at a muon collider. (orig.)

Summary of the Linear Collider Working Group

International Nuclear Information System (INIS)

Ruth, R.D.

1989-01-01

The focus of the Linear Collider Working Group was on a next generation linear collider. Topics discussed are: parameters; damping rings; bunch compression and pre-acceleration; linac; final focus; and multibunch effects. 8 refs., 3 figs., 7 tabs

Siting the superconducting super collider

International Nuclear Information System (INIS)

Price, R.; Rooney, R.C.

1988-01-01

At the request of the Department of Energy, the National Academy of Sciences and the National Academy of Engineering established the Super Collider Site Evaluation Committee to evaluate the suitability of proposed sites for the Superconducting Super Collider. Thirty-six proposals were examined by the committee. Using the set of criteria announced by DOE in its Invitation for Site Proposals, the committee identified eight sites that merited inclusion on a ''best qualified list.'' The list represents the best collective judgment of 21 individuals, carefully chosen for their expertise and impartiality, after a detailed assessment of the proposals using 19 technical subcriteria and DOE's life cycle cost estimates. The sites, in alphabetical order, are: Arizona/Maricopa; Colorado; Illinois; Michigan/Stockbridge; New York/Rochester; North Carolina; Tennessee; and Texas/Dallas-Fort Worth. The evaluation of these sites and the Superconducting Super Collider are discussed in this book

Physicist pins hopes on particle collider

CERN Multimedia

2007-01-01

Physicist pins hopes on particle collider By Deseret Morning News Published: Monday, Dec. 31, 27 12:4 a.m. MST FONT Scott Thomas, a 187 State University graduate, is working at the frontiers of science. The theoretical physicist is crafting ways to extract fundamental secrets that seem certain to be uncovered by the Large Hadron Collider.

Reduction of radiation effects by chemical protector (WR-2721)

International Nuclear Information System (INIS)

Lee, C.H.; Kim, Y.K.; Yun, T.K.; Koh, J.H.

1985-01-01

As a part studies on effect of radiation, the present report was carried out to evaluate the changes of leukocytes, lymphocytes percent of leukocytes and several organs in swiss webster (NIH-GP) mice by radiation protective agents prior to γ-ray exposure. The whole body irradiation after administration of a radiation protective agents was done in dose level of 25,50,100 and 300 rads by a single exposure of γ-ray delivered from 60 Co, source tele-irradiation unit at a dose rate of 100 rad/min. Mice of each experimental group were whole body γ-irradiated in plastic cage with special producted rotating machine. The radiation protective agent was employed WR-2721 and the amounts injected intraperitoneally were 400mg/kg of body weight. The leukocytes were counted with hemocytometer. Differential count of leukocytes was done with 200 cells every smear and lymphocyte percent of leukocyte were determined in relative proportion only. All major organ were examined grossly and weighted. After fixation with formalin solution, histo-pathological preparations were made for microscopical study. (Author)

Beamstrahlung spectra in next generation linear colliders

Energy Technology Data Exchange (ETDEWEB)

Barklow, T.; Chen, P. (Stanford Linear Accelerator Center, Menlo Park, CA (United States)); Kozanecki, W. (DAPNIA-SPP, CEN-Saclay (France))

1992-04-01

For the next generation of linear colliders, the energy loss due to beamstrahlung during the collision of the e{sup +}e{sup {minus}} beams is expected to substantially influence the effective center-of-mass energy distribution of the colliding particles. In this paper, we first derive analytical formulae for the electron and photon energy spectra under multiple beamstrahlung processes, and for the e{sup +}e{sup {minus}} and {gamma}{gamma} differential luminosities. We then apply our formulation to various classes of 500 GeV e{sup +}e{sup {minus}} linear collider designs currently under study.

The principles and construction of linear colliders

International Nuclear Information System (INIS)

Rees, J.

1986-09-01

The problems posed to the designers and builders of high-energy linear colliders are discussed. Scaling laws of linear colliders are considered. The problem of attainment of small interaction areas is addressed. The physics of damping rings, which are designed to condense beam bunches in phase space, is discussed. The effect of wake fields on a particle bunch in a linac, particularly the conventional disk-loaded microwave linac structures, are discussed, as well as ways of dealing with those effects. Finally, the SLAC Linear Collider is described. 18 refs., 17 figs

Physics at high energy photon photon colliders

International Nuclear Information System (INIS)

Chanowitz, M.S.

1994-06-01

I review the physic prospects for high energy photon photon colliders, emphasizing results presented at the LBL Gamma Gamma Collider Workshop. Advantages and difficulties are reported for studies of QCD, the electroweak gauge sector, supersymmetry, and electroweak symmetry breaking

The possible hindrance of a 8 MW wind farm along the Zuidermeerdijk in the Noordoostpolder, Netherlands, for birds

International Nuclear Information System (INIS)

Van den Bergh, L.M.J.; Spaans, A.L.

1993-01-01

The title farm comprises 16 three-bladed 500 kW wind turbines. Hindrance of wind turbines are collisions with the wind turbines and in the wake behind the blades and loss or disintegration of the natural habitat because of the presence of the wind turbines (aspect of disturbance). The title study is focused on counting the number of collision bird victims per year, and analyzing the disturbance effects on hibernating and foraging birds. It appeared that almost 150 to more than 1500 birds will collide with one of the 16 wind turbines. A few hundred tufted ducks, some tens of pochard and some tens of wild ducks per kilometre of the wind farm will leave their natural habitat. Based on the results it is concluded that the dike area between kilometre marker 32.5 and kilometre marker 35.5 is the most suitable area for a wind turbine array along the Zuidermeerdijk in between Schokkerhaven and Ketelbrug, both Netherlands. 3 figs., 5 tabs., 2 appendices, 33 refs

ERL-BASED LEPTON-HADRON COLLIDERS: eRHIC AND LHeC

CERN Document Server

Zimmermann, F

2013-01-01

Two hadron-ERL colliders are being proposed. The Large Hadron electron Collider (LHeC) plans to collide the high-energy protons and heavy ions in the Large Hadron Collider (LHC) at CERN with 60-GeV polarized electrons or positrons. The baseline scheme for this facility adds to the LHC a separate recirculating superconducting (SC) lepton linac with energy recovery, delivering a lepton current of 6.4mA. The electron-hadron collider project eRHIC aims to collide polarized (and unpolarized) electrons with a current of 50 (220) mA and energies in the range 5–30 GeV with a variety of hadron beams— heavy ions as well as polarized light ions— stored in the existing Relativistic Heavy Ion Collider (RHIC) at BNL. The eRHIC electron beam will be generated in an energy recovery linac (ERL) installed inside the RHIC tunnel.

The hypolipidemic activity of Ayurvedic medicine, Arogyavardhini vati in Triton WR-1339-induced hyperlipidemic rats: A comparison with fenofibrate.

Science.gov (United States)

Kumar, Gajendra; Srivastava, Amita; Sharma, Surinder Kumar; Gupta, Yogendra Kumar

2013-07-01

Hyperlipidemia is a major risk factor of coronary heart disease. Currently available hypolipidemic drugs have been associated with number of side effects. Arogyavardhini vati, an Ayurvedic polyherbal formulation has been used for liver disorders. Therefore, present study was designed to evaluate the effect of Arogyavardhini vati in Triton WR-1339-induced hyperlipidemia in rats. Anti-hyperlipidemic activity evaluation of Arogyavardhini vati against Triton WR-1339-induced hyperlipidemia in rats. Overnight fasted male Wistar rats (150-200 g) were randomly divided into normal control group [4% Dimethyl Sulfoxide (DMSO), i.p.], positive control group (Triton WR-1339 in 4% DMSO, 400 mg/kg, i.p.), standard drug treated (fenofibrate 65 mg/kg, p.o. for 7 days after inducing hyperlipidemia) and Arogyavardhini vati treated (50, 100, 200 mg/kg, p.o. for 7 days after inducing hyperlipidemia). Rat doses were calculated by extrapolating the equivalent human dose (therapeutic dose, sub-maximum, and maximum dose). Serum total cholesterol, triglyceride, low-density lipoprotein (LDL), high-density lipoprotein HDL, liver malondialdehyde (MDA), and glutathione (GSH) levels were estimated at end of experiments. Arogyavardhini vati significantly decreased serum cholesterol, triglyceride, LDL, and C-reactive protein (CRP) and significantly increased serum HDL in a dose-dependent manner. Decreased MDA and increased GSH levels in liver were observed at all doses of Arogyavardhini vati (50, 100, 200 mg/kg) and fenofibrate-treated groups when compared with Triton-treated group. Atherogenic Index (AI) level was significantly decreased in fenofibrate and Arogyavardhini vati (200 mg/kg) treated rats when compared with normal control. Arogyavardhini vati, a traditionally used Ayurvedic medicine may be a useful therapy for hypercholesterolemia through reducing oxidative stress (decreasing MDA and increasing GSH) and lipid levels.

Hadron collider luminosity limitations

CERN Document Server

Evans, Lyndon R

1992-01-01

The three colliders operated to date have taught us a great deal about the behaviour of both bunched and debunched beams in storage rings. The main luminosity limitations are now well enough understood that most of them can be stronglu attenuated or eliminated by approriate design precautions. Experience with the beam-beam interaction in both the SPS and the Tevatron allow us to predict the performance of the new generation of colliders with some degree of confidence. One of the main challenges that the accelerator physicist faces is the problem of the dynamic aperture limitations due to the lower field quality expected, imposed by economic and other constraints.

Future Circular Collider Study FCC-he Baseline Parameters

CERN Document Server

Bruning, Oliver; Klein, Max; Pellegrini, Dario; Schulte, Daniel; Zimmermann, Frank

2017-01-01

Initial considerations are presented on the FCC-he, the electron-hadron collider con guration within the Future Circular Collider study. This note considers arguments for the choice of the electron beam energy based on physics, ep scattering kinematics and cost. The default con guration for the electron accelerator, as for the LHeC, is chosen to be a multi-turn energy recovery linac external to the proton beam tunnel. The main accelerator parameters of the FCC-he are discussed, assuming the concurrent operation of ep with the 100TeV cms energy pp collider. These are compared with the LHeC design concept, for increased performance as for a Higgs facility using the HL-LHC, and also the high energy HE-LHC ep collider configuration. Initial estimates are also provided for the luminosity performance of electron-ion colliders for the 60 GeV electron ERL when combined with the LHC, the HE-LHC and the FCC ion beams.

Leptogenesis with TeV Scale WR

Science.gov (United States)

Gu, Pei-Hong; Mohapatra, Rabindra N.

2018-04-01

Successful leptogenesis within the conventional TeV-scale left-right implementation of type-I seesaw has been shown to require that the mass of the right-handed WR± boson should have a lower bound much above the reach of the Large Hadron Collider. This bound arises from the necessity to suppress the washout of lepton asymmetry due to WR±-mediated Δ L ≠0 processes. We show that in an alternative quark seesaw realization of left-right symmetry, the above bound can be avoided. Lepton asymmetry in this model is generated not via the usual right-handed neutrino decay but rather via the decay of new heavy scalars producing an asymmetry in the B -L carrying Higgs triplets responsible for type-II seesaw, whose decay leads to the lepton asymmetry.

Study of Collective Effects in the FCC-ee Collider

OpenAIRE

Zobov, Mikhail; Belli, Eleonora; Castorina, Giovanni; Migliorati, Mauro; Persichelli, Serena; Rumolo, Giovanni; Spataro, Bruno

2018-01-01

The Future Circular Collider (FCC) study aims at designing different options of a post-LHC collider. The high luminosity electron-positron collider FCC-ee based on the crab waist concept is considered as an intermediate step on the way towards FCC-hh, a 100 TeV hadron collider using the same tunnel of about 100 km. Due to a high intensity of circulating beams the impact of collective effects on FCC-ee performance has to be carefully analyzed. In this paper we evaluate beam coupling impedance ...

The future of the Large Hadron Collider and CERN.

Science.gov (United States)

Heuer, Rolf-Dieter

2012-02-28

This paper presents the Large Hadron Collider (LHC) and its current scientific programme and outlines options for high-energy colliders at the energy frontier for the years to come. The immediate plans include the exploitation of the LHC at its design luminosity and energy, as well as upgrades to the LHC and its injectors. This may be followed by a linear electron-positron collider, based on the technology being developed by the Compact Linear Collider and the International Linear Collider collaborations, or by a high-energy electron-proton machine. This contribution describes the past, present and future directions, all of which have a unique value to add to experimental particle physics, and concludes by outlining key messages for the way forward.

Status of the MEIC ion collider ring design

International Nuclear Information System (INIS)

Morozov, Vasiliy; Derbenev, Yaroslav; Harwood, Leigh; Hutton, Andrew; Lin, Fanglei; Pilat, Fulvia; Zhang, Yuhong; Cai, Yunhai; Nosochkov, Y. M.; Sullivan, Michael; Wang, M.-H.; Wienands, Uli; Gerity, James; Mann, Thomas; McIntyre, Peter; Pogue, Nathaniel; Sattarov, Akhdiyor

2015-09-01

We present an update on the design of the ion collider ring of the Medium-energy Electron-Ion Collider (MEIC) proposed by Jefferson Lab. The design is based on the use of super-ferric magnets. It provides the necessary momentum range of 8 to 100 GeV/c for protons and ions, matches the electron collider ring design using PEP-II components, fits readily on the JLab site, offers a straightforward path for a future full-energy upgrade by replacing the magnets with higher-field ones in the same tunnel, and is more cost effective than using presently available current-dominated super-conducting magnets. We describe complete ion collider optics including an independently-designed modular detector region.

Status of the MEIC ion collider ring design

International Nuclear Information System (INIS)

Morozov, V. S.; Derbenev, Ya. S.; Harwood, L.; Hutton, A.; Lin, F.; Pilat, F.; Zhang, Y.; Cai, Y.; Nosochkov, Y. M.; Sullivan, M.; Wang, M-H; Wienands, U.; Gerity, J.; Mann, T.; McIntyre, P.; Pogue, N. J.; Satttarov, A.

2015-01-01

We present an update on the design of the ion collider ring of the Medium-energy Electron-Ion Collider (MEIC) proposed by Jefferson Lab. The design is based on the use of super-ferric magnets. It provides the necessary momentum range of 8 to 100 GeV/c for protons and ions, matches the electron collider ring design using PEP-II components, fits readily on the JLab site, offers a straightforward path for a future full-energy upgrade by replacing the magnets with higher-field ones in the same tunnel, and is more cost effective than using presently available current-dominated superconducting magnets. We describe complete ion collider optics including an independently-designed modular detector region.

Phase I trials of WR2721 in combination with radiation therapy and with the alkylating agents cyclophosphamide and cis-platinum

Energy Technology Data Exchange (ETDEWEB)

Kligerman, M.M.; Blumberg, A.L.; Glick, J.H.; Nelson, D.F.; Glover, D.; Yuhas, J.M.; Amols, H.I.; Goodman, R.L.

Three phase I trials of the radioprotector S-2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721) have accessed 60 patients. Study 1 is devised to determine the maximum tolerated dose (MTD) of a single dose of the protector 15 to 30 minutes before a single radiation treatment of a size used routinely in palliative management. Study 2 plans to determine the MTD for up to 15 daily doses of the drug over 3 weeks during palliative radiotherapy. Also, the multipe-dose study will establish the MTD before palliative irradiation for fewer than five fractions a week. Study 3 uses the existing single-dose MTD determined in Study 1 as pretreatment 15 to 30 minutes before cyclophosphamide or cis-platinum. Toxic symptoms include emesis, hypotension, hypertension, somnolence, and sneezing. Only one serious episode of hypotension, considered idiosyncratic, and one instance of moderate to severe vomiting have occurred. Forty-one patients have been entered in Study 1 and a dose of 600 mg/m2 has been reached. The next step is to proceed to the planned highest level of 740 mg/m2. Of five patients in the multiple-dose study, one has been given, without toxicity, WR2721 at the level of 100 mg/m2 for 15 fractions over 3 weeks. Fourteen patients are accessed to the alkylating agent study. Using protector doses of 450 mg/m2, a cyclophosphamide level of 1500 mg/m2 has been accomplished. However, two of three patients who received 450 mg/m2 of WR2721 before 120 mg/m2 of cis-platinum have shown moderate elevation of the serum creatinine, both of which returned to normal.

Phase I trials of WR2721 in combination with radiation therapy and with the alkylating agents cyclophosphamide and cis-platinum

International Nuclear Information System (INIS)

Kligerman, M.M.; Blumberg, A.L.; Glick, J.H.; Nelson, D.F.; Glover, D.; Yuhas, J.M.; Amols, H.I.; Goodman, R.L.

1981-01-01

Three phase I trials of the radioprotector S-2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721) have accessed 60 patients. Study 1 is devised to determine the maximum tolerated dose (MTD) of a single dose of the protector 15 to 30 minutes before a single radiation treatment of a size used routinely in palliative management. Study 2 plans to determine the MTD for up to 15 daily doses of the drug over 3 weeks during palliative radiotherapy. Also, the multipe-dose study will establish the MTD before palliative irradiation for fewer than five fractions a week. Study 3 uses the existing single-dose MTD determined in Study 1 as pretreatment 15 to 30 minutes before cyclophosphamide or cis-platinum. Toxic symptoms include emesis, hypotension, hypertension, somnolence, and sneezing. Only one serious episode of hypotension, considered idiosyncratic, and one instance of moderate to severe vomiting have occurred. Forty-one patients have been entered in Study 1 and a dose of 600 mg/m2 has been reached. The next step is to proceed to the planned highest level of 740 mg/m2. Of five patients in the multiple-dose study, one has been given, without toxicity, WR2721 at the level of 100 mg/m2 for 15 fractions over 3 weeks. Fourteen patients are accessed to the alkylating agent study. Using protector doses of 450 mg/m2, a cyclophosphamide level of 1500 mg/m2 has been accomplished. However, two of three patients who received 450 mg/m2 of WR2721 before 120 mg/m2 of cis-platinum have shown moderate elevation of the serum creatinine, both of which returned to normal

Progress report on the SLAC Linear Collider

International Nuclear Information System (INIS)

Kozanecki, W.

1987-11-01

In this paper we report on the status of the SLAC Linear Collider (SLC), the prototype of a new generation of colliding beam accelerators. This novel type of machine holds the potential of extending electron-positron colliding beam studies to center-of-mass (c.m.) energies far in excess of what is economically achievable with colliding beam storage rings. If the technical challenges posed by linear colliders are solvable at a reasonable cost, this new approach would provide an attractive alternative to electron-positron rings, where, because of rapidly rising synchrotron radiation losses, the cost and size of the ring increases with the square of the c.m. energy. In addition to its role as a test vehicle for the linear collider principle, the SLC aims at providing an abundant source of Z 0 decays to high energy physics experiments. Accordingly, two major detectors, the upgraded Mark II, now installed on the SLC beam line, and the state-of-the-art SLD, currently under construction, are preparing to probe the Standard Model at the Z 0 pole. The SLC project was originally funded in 1983. Since the completion of construction, we have been commissioning the machine to bring it up to a performance level adequate for starting the high energy physics program. In the remainder of this paper, we will discuss the status, problems and performance of the major subsystems of the SLC. We will conclude with a brief outline of the physics program, and of the planned enhancements to the capabilities of the machine. 26 refs., 7 figs

Modelling seabird collision risk with off-shore wind farms

Energy Technology Data Exchange (ETDEWEB)

Mateos, Maria; Arroyo, Gonzalo Munoz; Rosario, Jose Juan Alonso del

2011-07-01

Full text: Recent concern about the adverse effects of collision mortality of avian migrants at wind farms has highlighted the need to understand bird-wind turbine interactions. Here, a stochastic collision model, based on data of seabird behaviour collected on- site, is presented, as a flexible and easy to take tool to assess the collisions probabilities of off-shore wind farms in a pre-construction phase. The collision prediction model considering the wind farm area as a risk window has been constructed as a stochastic model for avian migrants, based on Monte Carlo simulation. The model calculates the probable number of birds collided per time unit. Migration volume, wind farm dimensions, vertical and horizontal distribution of the migratory passage, flight direction and avoidance rates, between other variables, are taken into account in different steps of the model as the input variables. In order to assess the weighted importance of these factors on collision probability predictions, collision probabilities obtained from the set of scenarios resulting from the different combinations of the input variables were modelled by using Generalised Additive Models. The application of this model to a hypothetical project for erecting a wind farm at the Strait of Gibraltar showed that collision probability, and consequently mortality rates, strongly depend on the values of the avoidance rates taken into account, and the distribution of birds into the different altitude layers. These parameters should be considered as priorities to be addressed in post-construction studies. (Author)

Dark spectroscopy at lepton colliders

Science.gov (United States)

Hochberg, Yonit; Kuflik, Eric; Murayama, Hitoshi

2018-03-01

Rich and complex dark sectors are abundant in particle physics theories. Here, we propose performing spectroscopy of the mass structure of dark sectors via mono-photon searches at lepton colliders. The energy of the mono-photon tracks the invariant mass of the invisible system it recoils against, which enables studying the resonance structure of the dark sector. We demonstrate this idea with several well-motivated models of dark sectors. Such spectroscopy measurements could potentially be performed at Belle II, BES-III and future low-energy lepton colliders.

2005 Final Report: New Technologies for Future Colliders

International Nuclear Information System (INIS)

Peter McIntyre; Al McInturff

2005-01-01

This document presents an annual report on our long-term R and D grant for development of new technology for future colliders. The organizing theme of our development is to develop a compact high-field collider dipole, utilizing wind-and-react Nb3Sn coil fabrication, stress management, conductor optimization, bladder preload, and flux plate suppression of magnetization multipoles. The development trail for this new technology began over four years ago with the successful testing of TAMU12, a NbTi model in which we put to a first test many of the construction details of the high-field design. We have built TAMU2, a mirror-geometry dipole containing a single coil module of the 3-module set required for the 14 Tesla design. This first Nb3Sn model was built using ITER conductor which carries much less current than high-performance conductor but enables us to prove in practice our reaction bake and impregnation strategies with ''free'' superconductor. TAMU2 has been shipped to LBNL for testing. Work is beginning on the construction of TAMU3, which will contain two coil modules of the 14 Tesla design. TAMU3 has a design field of 13.5 Tesla and will enable us to fully evaluate the issues of stress management that will be important to the full design. With the completion of TAMU2 and the construction of TAMU3 the Texas A and M group ''comes of age'' in the family of superconducting magnet R and D laboratories. We have completed the phase of developing core technologies and fixtures and entered the phase of building and testing a succession of model dipoles that each build incrementally upon a proven core design

Investigations with beagles about toxicity and radioprotective effect of the chemical radioprotection substance WR 2721

International Nuclear Information System (INIS)

Wagner, M.; Sedlmeier, H.; Wustrow, T.; Messerschmidt, O.

1980-01-01

The toxicity of the chemical radioprotection substance WR 2721 (S-2-(3-aminopropylamino)ethyl-thiophosphate) was examined in 25 beagles. The study showed that the toxicity of the substance increases as the dose gets higher. Between the doses 200 and 250 mg/kg of body weight, the increase of toxicity was significantly greater than could be expected on the basis of the dose difference. Until a dose of 200 mg/kg, the authors found no side effects which would have disturbed vital functions, but higher doses led to marked symptoms of intoxication. (orig.) [de

The promise of the large collider

CERN Multimedia

2007-01-01

"In 2007, the most powerful particle accelerator ever built, CERN's new Large hadron Collider, will probe the secrets of matter in the energy states prevailing in the moments after the Big Bang. By colliding particles together when they are moving at close to the speed of ight, physicists hope to find out about matter in its earliest forms, using the energy produced by the collisions." (2 pages)

Technical challenge of future linear colliders

International Nuclear Information System (INIS)

Himel, T.

1986-05-01

The next generation of high energy e + e - colliders is likely to be built with colliding linear accelerators. A lot of research and development is needed before such a machine can be practically built. Some of the problems and recent progress made toward their solution are described here. Quantum corrections to beamstrahlung, the production of low emittance beams and strong focusing techniques are covered

Excited quark production at hadron colliders

International Nuclear Information System (INIS)

Baur, U.; Hinchliffe, I.; Zeppenfeld, D.

1987-06-01

Composite models generally predict the existence of excited quark and lepton states. We consider the production and experimental signatures of excited quarks Q* of spin and isospin 1/2 at hadron colliders and estimate the background for those channels which are most promising for Q* identification. Multi-TeV pp-colliders will give access to such particles with masses up to several TeV

Last magnet in place for colossal collider

CERN Document Server

Cho, Adrian

2007-01-01

"Workers have installed the last magnet for the world's mew highest-energy particle smasher, the Large Hadron Collider (LHC). The installation marks an important milestone; however, researchers still may not get the collider completed in time to start it up in November as planned." (1 page)

The Next Linear Collider: NLC2001

International Nuclear Information System (INIS)

Burke, D.

2002-01-01

Recent studies in elementary particle physics have made the need for an e + e - linear collider able to reach energies of 500 GeV and above with high luminosity more compelling than ever [1]. Observations and measurements completed in the last five years at the SLC (SLAC), LEP (CERN), and the Tevatron (FNAL) can be explained only by the existence of at least one particle or interaction that has not yet been directly observed in experiment. The Higgs boson of the Standard Model could be that particle. The data point strongly to a mass for the Higgs boson that is just beyond the reach of existing colliders. This brings great urgency and excitement to the potential for discovery at the upgraded Tevatron early in this decade, and almost assures that later experiments at the LHC will find new physics. But the next generation of experiments to be mounted by the world-wide particle physics community must not only find this new physics, they must find out what it is. These experiments must also define the next important threshold in energy. The need is to understand physics at the TeV energy scale as well as the physics at the 100-GeV energy scale is now understood. This will require both the LHC and a companion linear electron-positron collider. A first Zeroth-Order Design Report (ZDR) [2] for a second-generation electron-positron linear collider, the Next Linear Collider (NLC), was published five years ago. The NLC design is based on a high-frequency room-temperature rf accelerator. Its goal is exploration of elementary particle physics at the TeV center-of-mass energy, while learning how to design and build colliders at still higher energies. Many advances in accelerator technologies and improvements in the design of the NLC have been made since 1996. This Report is a brief update of the ZDR

The Next Linear Collider: NLC2001

Energy Technology Data Exchange (ETDEWEB)

D. Burke et al.

2002-01-14

Recent studies in elementary particle physics have made the need for an e{sup +}e{sup -} linear collider able to reach energies of 500 GeV and above with high luminosity more compelling than ever [1]. Observations and measurements completed in the last five years at the SLC (SLAC), LEP (CERN), and the Tevatron (FNAL) can be explained only by the existence of at least one particle or interaction that has not yet been directly observed in experiment. The Higgs boson of the Standard Model could be that particle. The data point strongly to a mass for the Higgs boson that is just beyond the reach of existing colliders. This brings great urgency and excitement to the potential for discovery at the upgraded Tevatron early in this decade, and almost assures that later experiments at the LHC will find new physics. But the next generation of experiments to be mounted by the world-wide particle physics community must not only find this new physics, they must find out what it is. These experiments must also define the next important threshold in energy. The need is to understand physics at the TeV energy scale as well as the physics at the 100-GeV energy scale is now understood. This will require both the LHC and a companion linear electron-positron collider. A first Zeroth-Order Design Report (ZDR) [2] for a second-generation electron-positron linear collider, the Next Linear Collider (NLC), was published five years ago. The NLC design is based on a high-frequency room-temperature rf accelerator. Its goal is exploration of elementary particle physics at the TeV center-of-mass energy, while learning how to design and build colliders at still higher energies. Many advances in accelerator technologies and improvements in the design of the NLC have been made since 1996. This Report is a brief update of the ZDR.

Wolf-Rayet nebulae

International Nuclear Information System (INIS)

Chu, You-Hua

2016-01-01

Since the discovery of nebulae around Wolf-Rayet (WR) stars in the 1960s, it has been established that WR stars are massive stars at advanced evolutionary stages and that their surrounding nebulae result from the interactions between the stellar mass loss and the ambient interstellar medium. Surveys of WR nebulae have been made in the Galaxy, Magellanic Clouds, and other nearby galaxies in the Local Group. Some WR nebulae exhibit He II λ4686 line emission, indicating stellar effective temperatures of 90 — 100 x 10 3 K. The shocked fast stellar winds from WR nebulae have been detected in soft X-rays, but theoretical models have not been able to reproduce the observed X-ray spectral properties. Elemental abundances of WR nebulae consisting of synthesized stellar material can constrain stellar evolution models, but high-dispersion spectra are needed to kinematically separate the expanding shell of a WR nebula and the background interstellar medium for accurate abundance analyses. (paper)

Anomalous Higgs couplings at an eγ collider

International Nuclear Information System (INIS)

Choudhury, Debajyoti; Mamta

2006-01-01

We examine the sensitivity of eγ colliders (based on e + e - linear colliders of c.m. energy 500 GeV) to the anomalous couplings of the Higgs to W-boson via the process e - γ→νWH. This has the advantage over e + e - collider in being able to dissociate WWH vertex from ZZH. We are able to construct several dynamical variables which may be used to constrain the various couplings in the WWH vertex

The International Linear Collider

Directory of Open Access Journals (Sweden)

List Benno

2014-04-01

Full Text Available The International Linear Collider (ILC is a proposed e+e− linear collider with a centre-of-mass energy of 200–500 GeV, based on superconducting RF cavities. The ILC would be an ideal machine for precision studies of a light Higgs boson and the top quark, and would have a discovery potential for new particles that is complementary to that of LHC. The clean experimental conditions would allow the operation of detectors with extremely good performance; two such detectors, ILD and SiD, are currently being designed. Both make use of novel concepts for tracking and calorimetry. The Japanese High Energy Physics community has recently recommended to build the ILC in Japan.

The International Linear Collider

Science.gov (United States)

List, Benno

2014-04-01

The International Linear Collider (ILC) is a proposed e+e- linear collider with a centre-of-mass energy of 200-500 GeV, based on superconducting RF cavities. The ILC would be an ideal machine for precision studies of a light Higgs boson and the top quark, and would have a discovery potential for new particles that is complementary to that of LHC. The clean experimental conditions would allow the operation of detectors with extremely good performance; two such detectors, ILD and SiD, are currently being designed. Both make use of novel concepts for tracking and calorimetry. The Japanese High Energy Physics community has recently recommended to build the ILC in Japan.

Wind farm related mortality among avian migrants - a remote sensing study and model analysis

DEFF Research Database (Denmark)

Desholm, M.

,136 migrating sea ducks only 47 individuals were predicted to collide with the wind turbine rotor-blades, equivalent to an overall mean collision risk of c. 0.02%. This thesis shows the added value of modelling in supplementing sound empirical studies in accessing the effects of major human development......This thesis is the result of a PhD study on bird-wind farm collisions and consists of a synopsis, five published papers, one submitted manuscript and another ready for submission. The papers describe the fi ndings from pre- and post-construction visual, radar and thermal imaging studies (1999......-2006) of migrating birds at the Nysted offshore wind farm in the Baltic Sea, Denmark. This thesis poses and answers the following questions: a) what hazard factors do offshore wind farming pose to wild birds, b) how should one choose the key focal species to study, c) how can remote sensing techniques be applied...

Physics beyond Colliders Kickoff Workshop

CERN Document Server

2016-01-01

The aim of the workshop is to explore the opportunities offered by the CERN accelerator complex and infrastructure to get new insights into some of today's outstanding questions in particle physics through projects complementary to high-energy colliders and other initiatives in the world. The focus is on fundamental physics questions that are similar in spirit to those addressed by high-energy colliders, but that may require different types of experiments. The kickoff workshop is intended to stimulate new ideas for such projects, for which we encourage the submission of abstracts.

Workshop on Physics Beyond Colliders

CERN Document Server

2016-01-01

The aim of the workshop is to explore the opportunities offered by the CERN accelerator complex and infrastructure to get new insights into some of today's outstanding questions in particle physics through projects complementary to high-energy colliders and other initiatives in the world. The focus is on fundamental physics questions that are similar in spirit to those addressed by high-energy colliders, but that may require different types of experiments. The kick-off workshop is intended to stimulate new ideas for such projects, for which we encourage the submission of abstracts.

Recent results from hadron colliders

International Nuclear Information System (INIS)

Frisch, H.J.

1990-01-01

This is a summary of some of the many recent results from the CERN and Fermilab colliders, presented for an audience of nuclear, medium-energy, and elementary particle physicists. The topics are jets and QCD at very high energies, precision measurements of electroweak parameters, the remarkably heavy top quark, and new results on the detection of the large flux of B mesons produced at these machines. A summary and some comments on the bright prospects for the future of hadron colliders conclude the talk. 39 refs., 44 figs., 3 tabs

Emittance control in linear colliders

International Nuclear Information System (INIS)

Ruth, R.D.

1991-01-01

Before completing a realistic design of a next-generation linear collider, the authors must first learn the lessons taught by the first generation, the SLC. Given that, they must make designs fault tolerant by including correction and compensation in the basic design. They must also try to eliminate these faults by improved alignment and stability of components. When these two efforts cross, they have a realistic design. The techniques of generation and control of emittance reviewed here provide a foundation for a design which can obtain the necessary luminosity in a next-generation linear collider

The Stanford Linear Collider

International Nuclear Information System (INIS)

Emma, P.

1995-01-01

The Stanford Linear Collider (SLC) is the first and only high-energy e + e - linear collider in the world. Its most remarkable features are high intensity, submicron sized, polarized (e - ) beams at a single interaction point. The main challenges posed by these unique characteristics include machine-wide emittance preservation, consistent high intensity operation, polarized electron production and transport, and the achievement of a high degree of beam stability on all time scales. In addition to serving as an important machine for the study of Z 0 boson production and decay using polarized beams, the SLC is also an indispensable source of hands-on experience for future linear colliders. Each new year of operation has been highlighted with a marked improvement in performance. The most significant improvements for the 1994-95 run include new low impedance vacuum chambers for the damping rings, an upgrade to the optics and diagnostics of the final focus systems, and a higher degree of polarization from the electron source. As a result, the average luminosity has nearly doubled over the previous year with peaks approaching 10 30 cm -2 s -1 and an 80% electron polarization at the interaction point. These developments as well as the remaining identifiable performance limitations will be discussed

Klystron switching power supplies for the Internation Linear Collider

Energy Technology Data Exchange (ETDEWEB)

Fraioli, Andrea; /Cassino U. /INFN, Pisa

2009-12-01

The International Linear Collider is a majestic High Energy Physics particle accelerator that will give physicists a new cosmic doorway to explore energy regimes beyond the reach of today's accelerators. ILC will complement the Large Hadron Collider (LHC), a proton-proton collider at the European Center for Nuclear Research (CERN) in Geneva, Switzerland, by producing electron-positron collisions at center of mass energy of about 500 GeV. In particular, the subject of this dissertation is the R&D for a solid state Marx Modulator and relative switching power supply for the International Linear Collider Main LINAC Radio Frequency stations.

Artist rendering of dust grains colliding at low speeds

Science.gov (United States)

2003-01-01

Clues to the formation of planets and planetary rings -- like Saturn's dazzling ring system -- may be found by studying how dust grains interact as they collide at low speeds. To study the question of low-speed dust collisions, NASA sponsored the COLLisions Into Dust Experiment (COLLIDE) at the University of Colorado. It was designed to spring-launch marble-size projectiles into trays of powder similar to space or lunar dust. COLLIDE-1 (1998) discovered that collisions below a certain energy threshold eject no material. COLLIDE-2 was designed to identify where the threshold is. In COLLIDE-2, scientists nudged small projectiles into dust beds and recorded how the dust splashed outward (video frame at top; artist's rendering at bottom). The slowest impactor ejected no material and stuck in the target. The faster impactors produced ejecta; some rebounded while others stuck in the target.

Photon Linear Collider Gamma-Gamma Summary

International Nuclear Information System (INIS)

Gronberg, J.

2012-01-01

High energy photon - photon collisions can be achieved by adding high average power short-pulse lasers to the Linear Collider, enabling an expanded physics program for the facility. The technology required to realize a photon linear collider continues to mature. Compton back-scattering technology is being developed around the world for low energy light source applications and high average power lasers are being developed for Inertial Confinement Fusion.

The Relativistic Heavy Ion Collider at Brookhaven

International Nuclear Information System (INIS)

Hahn, H.

1989-01-01

The conceptual design of a collider capable of accelerating and colliding heavy ions and to be constructed in the existing 3.8 km tunnel at Brookhaven has been developed. The collider has been designed to provide collisions of gold ions at six intersection points with a luminosity of about 2 x 10 26 cm -2 sec -1 at an energy per nucleon of 100 GeV in each beam. Collisions with different ion species, including protons, will be possible. The salient design features and the reasons for major design choices of the proposed machine are discussed in this paper. 28 refs., 2 figs., 1 tab

Higgs and SUSY searches at future colliders

Indian Academy of Sciences (India)

... searches at future colliders, particularly comparing and contrasting the capabilities of LHC and next linear collider (NLC), including the aspects of Higgs searches in supersymmetric theories. I will also discuss how the search and study of sparticles other than the Higgs can be used to give information about the parameters ...

XMM-Newton X-ray Observatory Guest Observer program (AO-1) at CASA

Science.gov (United States)

Skinner, Stephen L.

2003-01-01

In this research program, we obtained and analyzed X-ray observations of the Wolf-Rayet (WR) star WR 110 (HD 165688) using the XMM-Newton space-based observatory. Radio observations were also obtained using the Very Large Array (VLA) radio telescope located in New Mexico and operated by the Natl. Radio Astronomy Observatory (NRAO). This star was targeted for observations primarily because it is believed to be a single WR star without a companion. Single WR stars are thought to emit X-rays from cool plasma in shocks distributed throughout their powerful stellar winds. However, there has been little observational work done to test this idea since single WR stars are relatively weak X-ray sources and have been difficult to detect with previous generation telescopes. The launch of XMM-Newton provides a new telescope that is much more sensitive than its predecessors, allowing single WR stars to be studied in detail for the first time. X-ray emission was clearly detected from WR 110. Analysis of its spectrum yields a surprising result. Its X-ray emitting plasma is distributed over a range of temperatures and is dominated by relatively cool plasma with a characteristic temperature T is approximately 6 million K. Such plasma can be explained by existing theoretical wind shock models. However, the spectrum also shows hotter plasma whose temperature is uncertain but is thought to be in excess of T approximately 30 million K. The origin of this hotter plasma is yet unknown, but possible mechanisms are identified

Hot Gas in the Wolf–Rayet Nebula NGC 3199

Energy Technology Data Exchange (ETDEWEB)

Toalá, J. A.; Chu, Y.-H. [Institute of Astronomy and Astrophysics, Academia Sinica (ASIAA), Taipei 10617, Taiwan (China); Marston, A. P. [European Space Agency/STScI, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Guerrero, M. A. [Instituto de Astrofísica de Andalucía, IAA-CSIC, Glorieta de la Astronomía s/n, Granada E-18008 (Spain); Gruendl, R. A. [Department of Astronomy, University of Illinois, 1002 West Green Street, Urbana, IL 61801 (United States)

2017-09-01

The Wolf–Rayet (WR) nebula NGC 3199 has been suggested to be a bow shock around its central star, WR 18, which is presumably a runaway star, because optical images of the nebula show a dominating arc of emission southwest of the star. We present the XMM-Newton detection of extended X-ray emission from NGC 3199, unveiling the powerful effect of the fast wind from WR 18. The X-ray emission is brighter in the region southeast of the star and an analysis of the spectral properties of the X-ray emission reveals abundance variations: (i) regions close to the optical arc present nitrogen-rich gas enhanced by the stellar wind from WR 18 and (ii) gas at the eastern region exhibits abundances close to those reported for the nebular abundances derived from optical studies, which is a signature of an efficient mixing of the nebular material with the stellar wind. The dominant plasma temperature and electron density are estimated to be T ≈ 1.2 × 10{sup 6} K and n {sub e} = 0.3 cm{sup −3} with an X-ray luminosity in the 0.3–3.0 keV energy range of L {sub X} = 2.6 × 10{sup 34} erg s{sup −1}. Combined with information derived from Herschel and the recent Gaia first data release, we conclude that WR 18 is not a runaway star and that the formation, chemical variations, and the shape of NGC 3199 depend on the initial configuration of the interstellar medium.

FUTURE CIRCULAR COLLIDER LOGISTICS STUDY

CERN Document Server

Beißert, Ulrike; Kuhlmann, Gerd; Nettsträter, Andreas; Prasse, Christian; Wohlfahrt, Andreas

2018-01-01

The Large Hadron Collider (LHC) at the European Organization for Nuclear Research CERN in Geneva is the largest and most powerful collider in the world. CERN and its research and experimental infrastructure is not only a focus for the science community but is also very much in the public eye. With the Future Circular Collider (FCC) Study, CERN has begun to examine the feasibility of a new underground accelerator ring with a length of approximately 100 kilometres. Logistics is of great importance for the construction, assembly and operation of the FCC. During the planning, construction and assembly of the LHC, logistics proved to be one of the key factors. As the FCC is even larger than the LHC, logistics will also become more and more significant. This report therefore shows new concepts, methods and analytics for logistics, supply chain and transport concepts as part of the FCC study. This report deals with three different logistics aspects for the planning and construction phase of FCC: 1. A discussion of d...

Anomalous VVH interactions at a linear collider

Indian Academy of Sciences (India)

Abstract. We examine, in a model independent way, the sensitivity of a linear collider to the couplings of a light Higgs boson to a pair of gauge bosons, including the possibility of. CP violation. We construct several observables that probe the various possible anomalous couplings. For an intermediate mass Higgs, a collider ...

Anomalous VVH interactions at a linear collider

Indian Academy of Sciences (India)

We examine, in a model independent way, the sensitivity of a linear collider to the couplings of a light Higgs boson to a pair of gauge bosons, including the possibility of CP violation. We construct several observables that probe the various possible anomalous couplings. For an intermediate mass Higgs, a collider operating ...

Final focus systems for linear colliders

International Nuclear Information System (INIS)

Helm, R.; Irwin, J.

1992-08-01

Final focus systems for linear colliders present many exacting challenges in beam optics, component design, and beam quality. Efforts to resolve these problems as they relate to a new generation of linear colliders are under way at several laboratories around the world. We will outline criteria for final focus systems and discuss the current state of understanding and resolution of the outstanding problems. We will discuss tolerances on alignment, field quality and stability for optical elements, and the implications for beam parameters such as emittance, energy spread, bunch length, and stability in position and energy. Beam-based correction procedures, which in principle can alleviate many of the tolerances, will be described. Preliminary results from the Final Focus Test Beam (FFTB) under construction at SLAC will be given. Finally, we mention conclusions from operating experience at the Stanford Linear Collider (SLC)

Final focus systems for linear colliders

International Nuclear Information System (INIS)

Helm, R.; Irwing, J.

1992-01-01

Final focus systems for linear colliders present many exacting challenges in beam optics, component design, and beam quality. Efforts to resolve these problems as they relate to a new generation of linear colliders are under way at several laboratories around the world. We outline criteria for final focus systems and discuss the current state of understanding and resolution of the outstanding problems. We discuss tolerances on alignment, field quality and stability for optical elements, and the implications for beam parameters such as emittance, energy spread , bunch length, and stability in position and energy. Beam-based correction procedures, which in principle can alleviate many of the tolerances, are described. Preliminary results from the Final Focus Test Beam (FFTB) under construction at SLAC are given. Finally, we mention conclusions from operating experience at the Stanford Linear Collider (SLC). (Author) 16 refs., 4 tabs., 6 figs

Scaling linear colliders to 5 TeV and above

International Nuclear Information System (INIS)

Wilson, P.B.

1997-04-01

Detailed designs exist at present for linear colliders in the 0.5-1.0 TeV center-of-mass energy range. For linear colliders driven by discrete rf sources (klystrons), the rf operating frequencies range from 1.3 GHz to 14 GHz, and the unloaded accelerating gradients from 21 MV/m to 100 MV/m. Except for the collider design at 1.3 GHz (TESLA) which uses superconducting accelerating structures, the accelerating gradients vary roughly linearly with the rf frequency. This correlation between gradient and frequency follows from the necessity to keep the ac open-quotes wall plugclose quotes power within reasonable bounds. For linear colliders at energies of 5 TeV and above, even higher accelerating gradients and rf operating frequencies will be required if both the total machine length and ac power are to be kept within reasonable limits. An rf system for a 5 TeV collider operating at 34 GHz is outlined, and it is shown that there are reasonable candidates for microwave tube sources which, together with rf pulse compression, are capable of supplying the required rf power. Some possibilities for a 15 TeV collider at 91 GHz are briefly discussed

Concept for a Future Super Proton-Proton Collider

Energy Technology Data Exchange (ETDEWEB)

Tang, Jingyu; et al.

2015-07-12

Following the discovery of the Higgs boson at LHC, new large colliders are being studied by the international high-energy community to explore Higgs physics in detail and new physics beyond the Standard Model. In China, a two-stage circular collider project CEPC-SPPC is proposed, with the first stage CEPC (Circular Electron Positron Collier, a so-called Higgs factory) focused on Higgs physics, and the second stage SPPC (Super Proton-Proton Collider) focused on new physics beyond the Standard Model. This paper discusses this second stage.

Concept for a Future Super Proton-Proton Collider

CERN Document Server

Tang, Jingyu; Chai, Weiping; Chen, Fusan; Chen, Nian; Chou, Weiren; Dong, Haiyi; Gao, Jie; Han, Tao; Leng, Yongbin; Li, Guangrui; Gupta, Ramesh; Li, Peng; Li, Zhihui; Liu, Baiqi; Liu, Yudong; Lou, Xinchou; Luo, Qing; Malamud, Ernie; Mao, Lijun; Palmer, Robert B.; Peng, Quanling; Peng, Yuemei; Ruan, Manqi; Sabbi, GianLuca; Su, Feng; Su, Shufang; Stratakis, Diktys; Sun, Baogeng; Wang, Meifen; Wang, Jie; Wang, Liantao; Wang, Xiangqi; Wang, Yifang; Wang, Yong; Xiao, Ming; Xing, Qingzhi; Xu, Qingjin; Xu, Hongliang; Xu, Wei; Witte, Holger; Yan, Yingbing; Yang, Yongliang; Yang, Jiancheng; Yuan, Youjin; Zhang, Bo; Zhang, Yuhong; Zheng, Shuxin; Zhu, Kun; Zhu, Zian; Zou, Ye

2015-01-01

Following the discovery of the Higgs boson at LHC, new large colliders are being studied by the international high-energy community to explore Higgs physics in detail and new physics beyond the Standard Model. In China, a two-stage circular collider project CEPC-SPPC is proposed, with the first stage CEPC (Circular Electron Positron Collier, a so-called Higgs factory) focused on Higgs physics, and the second stage SPPC (Super Proton-Proton Collider) focused on new physics beyond the Standard Model. This paper discusses this second stage.

Leptoquark production at high energy e+e- colliders

International Nuclear Information System (INIS)

Bluemlein, J.; Boos, E.

1994-08-01

The prospects to search for scalar and vector leptoquarks at high energy e + e - colliders are reviewed. We compare production cross sections in the energy range between √s=O(200 GeV) and 1 TeV for e + e - annihilation. QED and QCD corrections and the effect of beamstrahlung in these processes are discussed. For the case of linear colliders the search potential in the different possible collider modes as e + e - annihilation, e ± γ scattering, and γγ fusion is compared. (orig.)

Numerical calculation of ion polarization in the NICA collider

Science.gov (United States)

Kovalenko, A. D.; Butenko, A. V.; Kekelidze, V. D.; Mikhaylov, V. A.; Kondratenko, M. A.; Kondratenko, A. M.; Filatov, Yu N.

2016-02-01

The NICA Collider with two solenoid Siberian snakes is “transparent” to the spin. The collider transparent to the spin provides a unique capability to control any polarization direction of protons and deuterons using additional weak solenoids without affecting orbital parameters of the beam. The spin tune induced by the control solenoids must significantly exceed the strength of the zero-integer spin resonance, which contains a coherent part associated with errors in the collider's magnetic structure and an incoherent part associated with the beam emittances. We present calculations of the coherent part of the resonance strength in the NICA collider for proton and deuteron beams.

Numerical calculation of ion polarization in the NICA collider

International Nuclear Information System (INIS)

Kovalenko, A D; Butenko, A V; Kekelidze, V D; Mikhaylov, V A; Filatov, Yu N; Kondratenko, M A; Kondratenko, A M

2016-01-01

The NICA Collider with two solenoid Siberian snakes is “transparent” to the spin. The collider transparent to the spin provides a unique capability to control any polarization direction of protons and deuterons using additional weak solenoids without affecting orbital parameters of the beam. The spin tune induced by the control solenoids must significantly exceed the strength of the zero-integer spin resonance, which contains a coherent part associated with errors in the collider's magnetic structure and an incoherent part associated with the beam emittances. We present calculations of the coherent part of the resonance strength in the NICA collider for proton and deuteron beams. (paper)

The Very Large Hadron Collider: The farthest energy frontier

International Nuclear Information System (INIS)

Barletta, William A.

2001-01-01

The Very Large Hadron Collider (or Eloisatron) represents what may well be the final step on the energy frontier of accelerator-based high energy physics. While an extremely high luminosity proton collider at 100-200 TeV center of mass energy can probably be built in one step with LHC technology, that machine would cost more than what is presently politically acceptable. This talk summarizes the strategies of collider design including staged deployment, comparison with electron-positron colliders, opportunities for major innovation, and the technical challenges of reducing costs to manageable proportions. It also presents the priorities for relevant R and D for the next few years

The SLAC linear collider

International Nuclear Information System (INIS)

Phinney, N.

1992-01-01

The SLAC Linear Collider has begun a new era of operation with the SLD detector. During 1991 there was a first engineering run for the SLD in parallel with machine improvements to increase luminosity and reliability. For the 1992 run, a polarized electron source was added and more than 10,000 Zs with an average of 23% polarization have been logged by the SLD. This paper discusses the performance of the SLC in 1991 and 1992 and the technical advances that have produced higher luminosity. Emphasis will be placed on issues relevant to future linear colliders such as producing and maintaining high current, low emittance beams and focusing the beams to the micron scale for collisions. (Author) tab., 2 figs., 18 refs

Physics prospects at a linear e+e− collider

Indian Academy of Sciences (India)

of various theories, there is need for a high luminosity e+e− collider ... International Technology Recommendation Panel took a decision that the collider ..... the presence of phases can affect the determination of the range of MSSM pa-.

Linear Collider Physics Resource Book Snowmass 2001

International Nuclear Information System (INIS)

Ronan, M.T.

2001-01-01

The American particle physics community can look forward to a well-conceived and vital program of experimentation for the next ten years, using both colliders and fixed target beams to study a wide variety of pressing questions. Beyond 2010, these programs will be reaching the end of their expected lives. The CERN LHC will provide an experimental program of the first importance. But beyond the LHC, the American community needs a coherent plan. The Snowmass 2001 Workshop and the deliberations of the HEPAP subpanel offer a rare opportunity to engage the full community in planning our future for the next decade or more. A major accelerator project requires a decade from the beginning of an engineering design to the receipt of the first data. So it is now time to decide whether to begin a new accelerator project that will operate in the years soon after 2010. We believe that the world high-energy physics community needs such a project. With the great promise of discovery in physics at the next energy scale, and with the opportunity for the uncovering of profound insights, we cannot allow our field to contract to a single experimental program at a single laboratory in the world. We believe that an e + e - linear collider is an excellent choice for the next major project in high-energy physics. Applying experimental techniques very different from those used at hadron colliders, an e + e - linear collider will allow us to build on the discoveries made at the Tevatron and the LHC, and to add a level of precision and clarity that will be necessary to understand the physics of the next energy scale. It is not necessary to anticipate specific results from the hadron collider programs to argue for constructing an e + e - linear collider; in any scenario that is now discussed, physics will benefit from the new information that e + e - experiments can provide. This last point merits further emphasis. If a new accelerator could be designed and built in a few years, it would make

Linear Collider Physics Resource Book Snowmass 2001

Energy Technology Data Exchange (ETDEWEB)

Ronan (Editor), M.T.

2001-06-01

The American particle physics community can look forward to a well-conceived and vital program of experimentation for the next ten years, using both colliders and fixed target beams to study a wide variety of pressing questions. Beyond 2010, these programs will be reaching the end of their expected lives. The CERN LHC will provide an experimental program of the first importance. But beyond the LHC, the American community needs a coherent plan. The Snowmass 2001 Workshop and the deliberations of the HEPAP subpanel offer a rare opportunity to engage the full community in planning our future for the next decade or more. A major accelerator project requires a decade from the beginning of an engineering design to the receipt of the first data. So it is now time to decide whether to begin a new accelerator project that will operate in the years soon after 2010. We believe that the world high-energy physics community needs such a project. With the great promise of discovery in physics at the next energy scale, and with the opportunity for the uncovering of profound insights, we cannot allow our field to contract to a single experimental program at a single laboratory in the world. We believe that an e{sup +}e{sup -} linear collider is an excellent choice for the next major project in high-energy physics. Applying experimental techniques very different from those used at hadron colliders, an e{sup +}e{sup -} linear collider will allow us to build on the discoveries made at the Tevatron and the LHC, and to add a level of precision and clarity that will be necessary to understand the physics of the next energy scale. It is not necessary to anticipate specific results from the hadron collider programs to argue for constructing an e{sup +}e{sup -} linear collider; in any scenario that is now discussed, physics will benefit from the new information that e{sup +}e{sup -} experiments can provide. This last point merits further emphasis. If a new accelerator could be designed and

High energy colliders

International Nuclear Information System (INIS)

Palmer, R.B.; Gallardo, J.C.

1997-02-01

The authors consider the high energy physics advantages, disadvantages and luminosity requirements of hadron (pp, p anti p), lepton (e + e - , μ + μ - ) and photon-photon colliders. Technical problems in obtaining increased energy in each type of machine are presented. The machines relative size are also discussed

Perspectives on large Linear Colliders

International Nuclear Information System (INIS)

Richter, B.

1987-01-01

The accelerator community now generally agrees that the Linear Collider is the most cost-effective technology for reaching much higher energies in the center-of-mass than can be attained in the largest of the e + e - storage rings, LEP. Indeed, even as the first linear collider, the SLC at SLAC, is getting ready to begin operations groups, at SLAC, Novosibirsk, CERN and KEK are doing R and D and conceptual design studies on a next generation machine in the 1 TeV energy region. In this perspectives talk I do not want to restrict my comments to any particular design, and so I will talk about a high-energy machine as the NLC, which is shorthand for the Next Linear Collider, and taken to mean a machine with a center-of-mass energy someplace in the 0.5 to 2 TeV energy range with sufficient luminosity to carry out a meaningful experimental program. I want to discuss three main items with you. The first is the interrelation of energy and luminosity requirements. These two items impose severe constraints on the accelerator builder. Next, I will give an introduction to linear collider design, concentrating on what goes on at the collision point, for still another constraint comes here from the beam-beam interaction which further restricts the choices available to the accelerator builder.Then, I want to give my impressions of the state of the technology available for building these kinds of machines within the next decade

International linear collider reference design report 2007

International Nuclear Information System (INIS)

Aarons, G.

2007-01-01

The International Linear Collider will give physicists a new cosmic doorway to explore energy regimes beyond the reach of today's accelerators. A proposed electron-positron collider, the ILC will complement the Large Hadron Collider, a proton-proton collider at the European Center for Nuclear Research (CERN) in Geneva, Switzerland, together unlocking some of the deepest mysteries in the universe. With LHC discoveries pointing the way, the ILC -- a true precision machine -- will provide the missing pieces of the puzzle. Consisting of two linear accelerators that face each other, the ILC will hurl some 10 billion electrons and their anti-particles, positrons, toward each other at nearly the speed of light. Superconducting accelerator cavities operating at temperatures near absolute zero give the particles more and more energy until they smash in a blazing crossfire at the centre of the machine. Stretching approximately 35 kilometres in length, the beams collide 14,000 times every second at extremely high energies -- 500 billion-electron-volts (GeV). Each spectacular collision creates an array of new particles that could answer some of the most fundamental questions of all time. The current baseline design allows for an upgrade to a 50-kilometre, 1 trillion-electron-volt (TeV) machine during the second stage of the project. This reference design provides the first detailed technical snapshot of the proposed future electron-positron collider, defining in detail the technical parameters and components that make up each section of the 31-kilometer long accelerator. The report will guide the development of the worldwide R and D program, motivate international industrial studies and serve as the basis for the final engineering design needed to make an official project proposal later this decade

Electron-positron colliders: looking at future physics

Energy Technology Data Exchange (ETDEWEB)

Anon.

1991-12-15

With research and development work underway throughout the world towards high energy electron-positron linear colliders, interest turns to the new physics these machines would open up. The first International Workshop on Physics and Experiments with Linear Colliders was held recently in Selkirk's in Finnish Lapland - some 300 kilometres north of the Arctic Circle.

Colliding beam physics at Fermilab: interaction regions, beam storage, antiproton cooling, production, and colliding

Energy Technology Data Exchange (ETDEWEB)

Walker, J.K. (ed.)

1977-01-01

The purpose of the colliding beams experment department at Fermilab was to bring about collisions of the stored beams in the energy doubler/saver and main ring, and construct experimental areas with appropriate detectors. To explore the feasibility of using the main ring as a storage device, several studies were carried out to investigate beam growth, loss, and the backgrounds in detectors at possible intersection regions. This range of developments constituted the major topics at the 1977 Summer Study reported here. Emphasis in part one is on interaction regions, beam storage, antiproton cooling, production, and colliding. 40 papers from this part are included in the data base. (GHT)

Status of the Future Circular Collider Study

CERN Document Server

AUTHOR|(CDS)2108454; Zimmermann, Frank

2016-01-01

Following the 2013 update of the European Strategy for Particle Physics, the international Future Circular Collider (FCC) Study has been launched by CERN as host institute. Its main purpose and long-term goal is to design an energyfrontier hadron collider (FCC-hh) with a centre-of-mass energy of about 100 TeV in a new 80–100 km tunnel. The FCC study also includes the design of a 90–350 GeV highluminosity lepton collider (FCC-ee) installed in the same tunnel, serving as Higgs, top and Z factory, as a potential intermediate step, as well as an electron-proton collider option (FCC-he). The physics cases for such machines are being assessed and concepts for experiments will be developed by the end of 2018, in time for the next update of the European Strategy for Particle Physics. This overview summarizes the status of machine designs and parameters, and it discusses the essential technical components being developed in the frame of the FCC study. Key elements are superconducting accelerator-dipole magnets wit...

CERN-Fermilab Hadron Collider Physics Summer School

CERN Multimedia

2007-01-01

Applications are now open for the 2nd CERN-Fermilab Hadron Collider Physics Summer School, which will take place at CERN from 6 to 15 June 2007. The school web site is http://cern.ch/hcpss with links to the academic program and application procedure. The application deadline is 9 March 2007. The results of the selection process will be announced shortly thereafter. The goal of the CERN-Fermilab Hadron Collider Physics Summer Schools is to offer students and young researchers in high energy physics a concentrated syllabus on the theory and experimental challenges of hadron collider physics. The first school in the series, held last summer at Fermilab, covered extensively the physics at the Tevatron collider experiments. The second school to be held at CERN, will focus on the technology and physics of the LHC experiments. Emphasis will be given on the first years of data-taking at the LHC and on the discovery potential of the programme. The series of lectures will be  supported by in-depth discussion sess...

Higgs measurement at $e^+e^-$ circular colliders

CERN Document Server

Ruan, Manqi

2016-01-01

Now that the mass of the Higgs boson is known, circular electron positron colliders, able to measure the properties of these particles with high accuracy, are receiving considerable attention. Design studies have been launched (i) at CERN with the Future Circular Colliders (FCC), of which an e+e- collider is a potential first step (FCC-ee, formerly caller TLEP) and (ii) in China with the Circular Electron Positron Collider (CEPC). Hosted in a tunnel of at least 50 km (CEPC) or 80-100 km (FCC), both projects can deliver very high luminosity from the Z peak to HZ threshold (CEPC) and even to the top pair threshold and above (FCC-ee). At the ZH production optimum, around 240 GeV, the FCC-ee (CEPC) will be able to deliver 10 (5) ab-1 integrated luminosity in 5 (10) years with 4 (2) interaction points: hence to produce millions of Higgs bosons through the Higgsstrahlung process and vector boson fusion processes. This sample opens the possibility of subper- cent precision absolute measurements of the Higgs boson co...

Higgs Measurement at e+e- Circular Colliders

CERN Document Server

Ruan, M

2014-01-01

Now that the mass of the Higgs boson is known, circular electron positron colliders, able to measure the properties of these particles with high accuracy, are receiving considerable attention. Design studies have been launched (i) at CERN with the Future Circular Colliders (FCC), of which an e+e- collider is a potential first step (FCC-ee, formerly caller TLEP) and (ii) in China with the Circular Electron Positron Collider (CEPC). Hosted in a tunnel of at least 50 km (CEPC) or 80-100 km (FCC), both projects can deliver very high luminosity from the Z peak to HZ threshold (CEPC) and even to the top pair threshold and above (FCC-ee). At the ZH production optimum, around 240 GeV, the FCC-ee (CEPC) will be able to deliver 10 (5) ab-1 integrated luminosity in 5 (10) years with 4 (2) interaction points: hence to produce millions of Higgs bosons through the Higgsstrahlung process and vector boson fusion processes. This sample opens the possibility of subper-cent precision absolute measurements of the Higgs boson cou...

Wind farm related mortality among avian migrants - a remote sensing study and model analysis

Energy Technology Data Exchange (ETDEWEB)

Desholm, M

2006-11-15

This thesis is the result of a PhD study on bird-wind farm collisions and consists of a synopsis, five published papers, one submitted manuscript and another ready for submission. The papers describe the findings from pre- and post-construction visual, radar and thermal imaging studies (1999-2006) of migrating birds at the Nysted offshore wind farm in the Baltic Sea, Denmark. This thesis poses and answers the following questions: a) what hazard factors do offshore wind farming pose to wild birds, b) how should one choose the key focal species to study, c) how can remote sensing techniques be applied to the study of bird wind farm interactions, and d) specifically, how do water birds react when approaching an offshore wind farm? The main aim of the study was the development of a predictive bird-wind farm collision model that incorporates the avoidance rate of birds at multiple scales. Out of 235,136 migrating sea ducks only 47 individuals were predicted to collide with the wind turbine rotor-blades, equivalent to an overall mean collision risk of c. 0.02%. This thesis shows the added value of modelling in supplementing sound empirical studies in accessing the effects of major human development pressures on migratory bird populations. (au)

Prospects for heavy flavor physics at hadron colliders

International Nuclear Information System (INIS)

Butler, J.N.

1997-09-01

The role of hadron colliders in the observation and study of CP violation in B decays is discussed. We show that hadron collider experiments can play a significant role in the early studies of these phenomena and will play an increasingly dominant role as the effort turns towards difficult to measure decays, especially those of the B s meson, and sensitive searches for rare decays and subtle deviations from Standard Model predictions. We conclude with a discussion of the relative merits of hadron collider detectors with 'forward' vs 'central' rapidity coverage

Beamstrahlung spectra in next generation linear colliders. Revision

Energy Technology Data Exchange (ETDEWEB)

Barklow, T.; Chen, P. [Stanford Linear Accelerator Center, Menlo Park, CA (United States); Kozanecki, W. [DAPNIA-SPP, CEN-Saclay (France)

1992-04-01

For the next generation of linear colliders, the energy loss due to beamstrahlung during the collision of the e{sup +}e{sup {minus}} beams is expected to substantially influence the effective center-of-mass energy distribution of the colliding particles. In this paper, we first derive analytical formulae for the electron and photon energy spectra under multiple beamstrahlung processes, and for the e{sup +}e{sup {minus}} and {gamma}{gamma} differential luminosities. We then apply our formulation to various classes of 500 GeV e{sup +}e{sup {minus}} linear collider designs currently under study.

TOP AND HIGGS PHYSICS AT THE HADRON COLLIDERS

Energy Technology Data Exchange (ETDEWEB)

Jabeen, Shabnam

2013-10-20

This review summarizes the recent results for top quark and Higgs boson measurements from experiments at Tevatron, a proton–antiproton collider at a center-of-mass energy of √ s =1 . 96 TeV, and the Large Hadron Collider, a proton–proton collider at a center- of-mass energy of √ s = 7 TeV. These results include the discovery of a Higgs-like boson and measurement of its various properties, and measurements in the top quark sector, e.g. top quark mass, spin, charge asymmetry and production of single top quark.

Electron-positron colliders: looking at future physics

International Nuclear Information System (INIS)

Anon.

1991-01-01

With research and development work underway throughout the world towards high energy electron-positron linear colliders, interest turns to the new physics these machines would open up. The first International Workshop on Physics and Experiments with Linear Colliders was held recently in Selkirk's in Finnish Lapland - some 300 kilometres north of the Arctic Circle

Effects of wind turbines on birds. What needs to be taken into account in Finland

International Nuclear Information System (INIS)

Walsh, M.

1997-01-01

The author examines the current knowledge on bird fatalities from wind turbines. As the number of turbines around the Finnish coast increases, concern has been voiced by some ornithologists for the safety of birds, particularly during migration. However, studies confirm that few birds collide with wind turbines during the day, with the exception of some large birds of prey that sometimes attempt to use the tower or blades for perching. At night the collision risk is somewhat higher, but average collision rates per kilometre of wind turbines placed in a row (including the space between individual machines) is no higher than that per kilometre of motorway, an acceptable figure in view of the relatively low numbers of machines compared to roads. Wind turbines can potentially do more serious damage to birds if they are erected too near large breeding concentrations, e.g. important coastal wetlands. Many groups of water and wading birds avoid feeding or nesting near turbines up to a range of 500-700 metres. (orig.)

Detectors for Linear Colliders: Calorimetry at a Future Electron-Positron Collider (3/4)

CERN Multimedia

CERN. Geneva

2010-01-01

Calorimetry will play a central role in determining the physics reach at a future e+e- collider. The requirements for calorimetry place the emphasis on achieving an excellent jet energy resolution. The currently favoured option for calorimetry at a future e+e- collider is the concept of high granularity particle flow calorimetry. Here granularity and a high pattern recognition capability is more important than the single particle calorimetric response. In this lecture I will describe the recent progress in understanding the reach of high granularity particle flow calorimetry and the related R&D efforts which concentrate on test beam demonstrations of the technological options for highly granular calorimeters. I will also discuss alternatives to particle flow, for example the technique of dual readout calorimetry.

Large Hadron Collider

CERN Multimedia

2007-01-01

"In the spring 2008, the Large Hadron Collider (LHC) machine at CERN (the European Particle Physics laboratory) will be switched on for the first time. The huge machine is housed in a circular tunnel, 27 km long, excavated deep under the French-Swiss border near Geneva." (1,5 page)

2nd CERN-Fermilab Hadron Collider Physics Summer School

CERN Document Server

Gian Giudice; Ellis, Nick; Jakobs, Karl; Mage, Patricia; Seymour, Michael H; Spiropulu, Maria; Wilkinson, Guy; CERN-FNAL Summer School; Hadron Collider Physics Summer School

2007-01-01

For the past few years, experiments at the Fermilab Tevatron Collider have once again been exploring uncharted territory at the current energy frontier of particle physics. With CERN's LHC operations to start in 2007, a new era in the exploration of the fundamental laws of nature will begin. In anticipation of this era of discovery, Fermilab and CERN are jointly organizing a series of "Hadron Collider Physics Summer Schools", whose main goal is to offer a complete picture of both the theoretical and experimental aspects of hadron collider physics. Preparing young researchers to tackle the current and anticipated challenges at hadron colliders, and spreading the global knowledge required for a timely and competent exploitation of the LHC physics potential, are concerns equally shared by CERN, the LHC host laboratory, and by Fermilab, the home of the Tevatron and host of CMS's LHC Physics Center in the U.S. The CERN-Fermilab Hadron Collider Physics Summer School is targeted particularly at young postdocs in exp...

SuperB: Next-Generation e+e− B-factory Collider

CERN Document Server

Novokhatski, A; Chao, A; Nosochkov, Y; Seeman, J T; Sullivan, M K; Wienands, J T; Wittmer, W; Baylac, M A; Bourrion, O; Monseu, N; Vescovi, C; Bettoni, S; Biagini, M E; Boni, R; Boscolo, M; Demma, T; Drago, A; Esposito, M; Guiducci, S; Preger, M A; Raimondi, P; Tomassini, S; Zobov, M; Bogomyagkov, A V; Nikitin, S A; Piminov, P A; Shatilov, D N; Sinyatkin, S V; Vobly, P; Bolzon, B; Brunetti, L; Jeremie, A; A. Chancé; Fabbricatore, P; Farinon, S; Musenich, R; Liuzzo, S M; Paoloni, E; Okunev, I N; Poirier, F; Rimbault, C; Variola, A

2011-01-01

The SuperB international team continues to optimize the design of an electron-positron collider, which will allow the enhanced study of the origins of flavor physics. The project combines the best features of a linear collider (high single-collision luminosity) and a storage-ring collider (high repetition rate), bringing together all accelerator physics aspects to make a very high luminosity of 1036 cm-2 s-1. This asymmetric-energy collider with a polarized electron beam will produce hundreds of millions of B-mesons at the Y(4S) resonance. The present design is based on extremely low emittance beams colliding at a large Piwinski angle to allow very low ßy* without the need for ultra short bunches. Use of crab-waist sextupoles will enhance the luminosity, suppressing dangerous resonances and allowing for a higher beam-beam parameter. The project has flexible beam parameters, improved dynamic aperture, and spin-rotators in the Low Energy Ring for longitudinal polarization of the electron beam at the Interactio...

A mathematical model of bird collisions with wind turbine rotors

International Nuclear Information System (INIS)

Tucker, V.A.

1996-01-01

When a bird flies through the disk swept out by the blades of a wind turbine rotor, the probability of collision depends on the motions and dimensions of the bird and the blades. The collision model in this paper predicts the probability for birds that glide upwind, downwind, an across the wind past simple one-dimensional blades represented by straight lines, and upwind and downwind past more realistic three-dimensional blades with chord and twist. Probabilities vary over the surface of the disk, and in most cases, the tip of the blade is less likely to collide with a bird than parts of the blade nearer the hub. The mean probability may be found by integration over the disk area. The collision model identifies the rotor characteristics that could be altered to make turbines safer for birds

From the LHC to Future Colliders

Energy Technology Data Exchange (ETDEWEB)

De Roeck, A.; Ellis, J.; /CERN; Grojean, C.; Heinemeyer, S.; /Cantabria Inst. of Phys.; Jakobs, K.; /Freiburg U.; Weiglein, G.; /Durham U., IPPP; Azuelos, G.; /TRIUMF; Dawson, S.; /Brookhaven; Gripaios, B.; /CERN; Han, T.; /Wisconsin U., Madison; Hewett, J.; /SLAC; Lancaster, M.; /University Coll. London; Mariotti, C.; /INFN, Turin; Moortgat, F.; /Zurich, ETH; Moortgat-Pick, G.; /Durham U., IPPP; Polesello, G.; /INFN, Pavia; Riemann, S.; /DESY; Assamagan, K.; /Brookhaven; Bechtle, P.; /DESY; Carena, M.; /Fermilab; Chachamis, G.; /PSI, Villigen /Taiwan, Natl. Taiwan U. /INFN, Florence /Bonn U. /CERN /Bonn U. /Freiburg U. /Oxford U. /Louvain U., CP3 /Bangalore, Indian Inst. Sci. /INFN, Milan Bicocca /Munich, Max Planck Inst. /Taiwan, Natl. Taiwan U. /Frascati /Fermilab /Warsaw U. /Florida U. /Orsay, LAL /LPSC, Grenoble /Warsaw U. /Yale U. /Stockholm U., Math. Dept. /Durham U., IPPP /DESY /Rome U. /University Coll. London /UC, San Diego /Heidelberg U. /Florida State U. /SLAC /Durham U., IPPP /Southern Denmark U., CP3-Origins /McGill U. /Durham U., IPPP; /more authors..

2010-06-11

Discoveries at the LHC will soon set the physics agenda for future colliders. This report of a CERN Theory Institute includes the summaries of Working Groups that reviewed the physics goals and prospects of LHC running with 10 to 300 fb{sup -1} of integrated luminosity, of the proposed sLHC luminosity upgrade, of the ILC, of CLIC, of the LHeC and of a muon collider. The four Working Groups considered possible scenarios for the first 10 fb{sup -1} of data at the LHC in which (i) a state with properties that are compatible with a Higgs boson is discovered, (ii) no such state is discovered either because the Higgs properties are such that it is difficult to detect or because no Higgs boson exists, (iii) a missing-energy signal beyond the Standard Model is discovered as in some supersymmetric models, and (iv) some other exotic signature of new physics is discovered. In the contexts of these scenarios, theWorking Groups reviewed the capabilities of the future colliders to study in more detail whatever new physics may be discovered by the LHC. Their reports provide the particle physics community with some tools for reviewing the scientific priorities for future colliders after the LHC produces its first harvest of new physics from multi-TeV collisions.

Factors associated with bat mortality at wind energy facilities in the United States

Science.gov (United States)

Thompson, Maureen; Beston, Julie A.; Etterson, Matthew A.; Diffendorfer, James E.; Loss, Scott R.

2017-01-01

Hundreds of thousands of bats are killed annually by colliding with wind turbines in the U.S., yet little is known about factors causing variation in mortality across wind energy facilities. We conducted a quantitative synthesis of bat collision mortality with wind turbines by reviewing 218 North American studies representing 100 wind energy facilities. This data set, the largest compiled for bats to date, provides further evidence that collision mortality is greatest for migratory tree-roosting species (Hoary Bat [Lasiurus cinereus], Eastern Red Bat [Lasiurus borealis], Silver-haired Bat [Lasionycteris noctivagans]) and from July to October. Based on 40 U.S. studies meeting inclusion criteria and analyzed under a common statistical framework to account for methodological variation, we found support for an inverse relationship between bat mortality and percent grassland cover surrounding wind energy facilities. At a national scale, grassland cover may best reflect openness of the landscape, a factor generally associated with reduced activity and abundance of tree-roosting species that may also reduce turbine collisions. Further representative sampling of wind energy facilities is required to validate this pattern. Ecologically informed placement of wind energy facilities involves multiple considerations, including not only factors associated with bat mortality, but also factors associated with bird collision mortality, indirect habitat-related impacts to all species, and overall ecosystem impacts.

Searches for supersymmetry at high-energy colliders

International Nuclear Information System (INIS)

Feng, Jonathan L.; Grivaz, Jean-Francois; Nachtman, Jane

2010-01-01

This review summarizes the state of the art in searches for supersymmetry at colliders on the eve of the Large Hadron Collider era. Supersymmetry is unique among extensions of the standard model in being motivated by naturalness, dark matter, and force unification, both with and without gravity. At the same time, weak-scale supersymmetry encompasses a wide range of experimental signals that are also found in many other frameworks. Motivations for supersymmetry are recalled and the various models and their distinctive features are reviewed. Searches for neutral and charged Higgs bosons and standard-model superpartners at the high energy frontier are summarized comprehensively, considering both canonical and noncanonical supersymmetric models, and including results from the LEP collider at CERN, HERA at DESY, and the Fermilab Tevatron.

The Superconducting Super Collider: A status report

International Nuclear Information System (INIS)

Schwitters, R.F.

1993-04-01

The design of the Superconducting Super Collider (SSC) is briefly reviewed, including its key machine parameters. The scientific objectives are twofold: (1) investigation of high-mass, low-rate, rare phenomena beyond the standard model; and (2) investigation of processes within the domain of the standard model. Machine luminosity, a key parameter, is a function of beam brightness and current, and it must be preserved through the injector chain. Features of the various injectors are discussed. The superconducting magnet system is reviewed in terms of model magnet performance, including the highly successful Accelerator System String Test Various magnet design modifications are noted, reflecting minor changes in the collider arcs and improved installation procedures. The paper concludes with construction scenarios and priority issues for ensuring the earliest collider commissioning

FERMILAB: Preparing to collide

International Nuclear Information System (INIS)

Anon.

1992-01-01

Against the background of stringent Environment, Safety and Health (ES&H) regulations mandated by the US Department of Energy for all national Labs, Fermilab prepared to mount the next major Tevatron proton-antiproton collider run

Beam instrumentation for the Tevatron Collider

Energy Technology Data Exchange (ETDEWEB)

Moore, Ronald S.; Jansson, Andreas; Shiltsev, Vladimir; /Fermilab

2009-10-01

The Tevatron in Collider Run II (2001-present) is operating with six times more bunches and many times higher beam intensities and luminosities than in Run I (1992-1995). Beam diagnostics were crucial for the machine start-up and the never-ending luminosity upgrade campaign. We present the overall picture of the Tevatron diagnostics development for Run II, outline machine needs for new instrumentation, present several notable examples that led to Tevatron performance improvements, and discuss the lessons for future colliders.

Wolf-Rayet phenomena

International Nuclear Information System (INIS)

Conti, P.S.

1982-01-01

The author reviews in broad terms the concept of Wolf-Rayet (W-R) phenomena, outlines what we currently know about the properties of stars showing such phenomena and indicates the directions in which future work is leading. He begins by listing the characteristics of W-R spectra and then considers the following specific problems: the absolute visual magnitudes; the heterogeneity of WN spectra; the existence of transition type spectra and compositions; the mass loss rates; the existence of very luminous and possibly very massive W-R stars. He discusses briefly our current understanding of the theoretical aspects of stellar evolution and stellar winds and the various scenarios that have been proposed to understand W-R stars. (Auth.)

Particle production at collider energies

International Nuclear Information System (INIS)

Geich-Gimbel, C.

1987-11-01

Key features of the SPS panti p Collider and the detectors of the UA-experiments involved are dealt with in chapter 2, which includes and accord to the ramping mode of the Collider, which allowed to raise the c.m. energy to 900 GeV in the UA5/2 experiment. The following chapters concentrate on physics results. Starting with a discussion of cross sections and diffraction dissociation in chapter 3 we then continue with a presentation of basic features of particle production such as rapidity and multiplicity distributions in chapter 4. There one of the unexpected findings at Collider energies, the breakdown of the so-called KNO-scaling, and new regularities potentially governing multiplicity distributions, are discussed. The findings about correlations among the final state particles, which may tell about the underlying dynamics of multi-particle production and be relevant to models thereof, are described in due detail in chapter 5. Transverse spectra and their trends with energy are shown in chapter 6. Results on identified particles are collected in a separate chapter in order to stress that this piece of information was an important outcome of the UA5 experiment. (orig./HSI)

Prospects for physics at e+e- linear colliders

International Nuclear Information System (INIS)

Feldman, G.J.

1988-03-01

The present thinking on high-energy e/sup /plus//e/sup /minus// linear colliders is reviewed, stressing those points that have consequences for detector design and physics analyses. Detector requirements are discussed. Experimental aspects of the physics that can be done at these colliders are discussed: first the general physics environment, then a standard process, W/sup /plus// W/sup /minus// detection, and finally four examples of the discovery potential of these colliders /emdash/ heavy quarks, heavy leptons, standard Higgs bosons, and charged Higgs bosons. The conclusions of this study will be stated. 23 refs., 40 figs

Final Cooling for a Muon Collider

Energy Technology Data Exchange (ETDEWEB)

Acosta Castillo, John Gabriel [Univ. of Mississippi, Oxford, MS (United States)

2017-05-01

To explore the new energy frontier, a new generation of particle accelerators is needed. Muon colliders are a promising alternative, if muon cooling can be made to work. Muons are 200 times heavier than electrons, so they produce less synchrotron radiation, and they behave like point particles. However, they have a short lifetime of 2.2 $\\mathrm{\\mu s}$ and the beam is more difficult to cool than an electron beam. The Muon Accelerator Program (MAP) was created to develop concepts and technologies required by a muon collider. An important effort has been made in the program to design and optimize a muon beam cooling system. The goal is to achieve the small beam emittance required by a muon collider. This work explores a final ionization cooling system using magnetic quadrupole lattices with a low enough $\\beta^{\\star} $ region to cool the beam to the required limit with available low Z absorbers.

SUPERCONDUCTING SOLENOIDS FOR THE MUON COLLIDER

Energy Technology Data Exchange (ETDEWEB)

GREEN,M.A.; EYSSA,Y.; KENNY,S.; MILLER,J.R.; PRESTEMON,S.; WEGGEL,R.J.

2000-06-12

The muon collider is a new idea for lepton colliders. The ultimate energy of an electron ring is limited by synchrotron radiation. Muons, which have a rest mass that is 200 times that of an electron can be stored at much higher energies before synchrotron radiation limits ring performance. The problem with muons is their short life time (2.1 {micro}s at rest). In order to operate a muon storage ring large numbers of muon must be collected, cooled and accelerated before they decay to an electron and two neutrinos. As the authors see it now, high field superconducting solenoids are an integral part of a muon collider muon production and cooling systems. This report describes the design parameters for superconducting and hybrid solenoids that are used for pion production and collection, RF phase rotations of the pions as they decay into muons and the muon cooling (reduction of the muon emittance) before acceleration.

The antiproton ion collider at FAIR

International Nuclear Information System (INIS)

Fabbietti, L.; Faestermann, T.; Homolka, J.; Kienle, P.; Kruecken, R.; Ring, P.; Suziki, K.; Beller, P.; Bosch, F.; Frankze, B.; Kozhuharov, C.; Nolden, F.; Cargnelli, M.; Fuhrmann, H.; Hirtl, A.; Marton, J.; Widmann, E.; Zmeskal, J.; Hayano, R.S.; Yamaguchi, T.; Lenske, H.; Litvinov, Y.; Shatunov, Y.; Skrinsky, A.N.; Vostrikov, V.A.; Wycech, S.

2005-01-01

A novel method is proposed to determine the charge and the matter radii instable and short lived nuclei using an pBar-A collider. The experiment makes use of the appropriately modified electron-ion collider Elise, to collide 30 MeV anti-protons with 740 AMeV ions. The anti-protons are first collected in the CR ring with 3 GeV energy and then cooled in the RESR ring to 30 MeV. The heavy ions produced in the SFRS are precooled in the CR ring, cooled in the RESR ring to 740 AMeV and fed to the NESR ring. The total pBar-nucleon annihilation cross-section is measured detecting the loss of stored ions and the pBar-n, pBar-p cross-sections detecting the A - 1 (Z - 1 or N - 1) nuclei left over after the annihilation, using the Schottcky method. Theoretical predictions show that the annihilation cross-section is proportional to the mean squared radius. (author)

Colliding muons

International Nuclear Information System (INIS)

Anon.

1994-01-01

Is a muon-muon collider really practical? That is the question being asked by Bob Palmer. Well known in particle physics, Palmer, with Nick Samios and Ralph Shutt, recently won the American Physical Society's Panofsky Prize for their 1964 discovery of the omega minus. As well as contributing to other major experiments, both at CERN and in the US, he has contributed ideas to stochastic cooling and novel acceleration schemes

Radioprotective effects of Sipunculus nudus L. polysaccharide combined with WR-2721, rhIL-11 and rhG-CSF on radiation-injured mice

International Nuclear Information System (INIS)

Jiang Shuqi; Shen Xianrong; Liu Yuming; He Ying; Jiang Dingwen; Chen Wei

2015-01-01

This study investigated the radioprotective effect of Sipunculus nudus L. polysaccharide (SNP) in combination with WR-2721, rhIL-11 and rhG-CSF on irradiated mice. A total of 70 Imprinting Control Region (ICR) mice were divided into seven groups: the control group, the model group and five administration groups. All groups, except the control group, were exposed to a 5 Gy 60 Co γ-ray beam. Blood parameters [including white blood cell (WBC), red blood cell (RBC) and platelet counts and hemoglobin level] were assessed three days before irradiation, and the on the 3rd, 7th and 14th days after irradiation. Spleen, thymus and testicular indices, DNA contents of bone marrow cells, bone marrow nucleated cells, sperm counts, superoxide dismutase (SOD), malondialdehyde (MDA), testosterone and estradiol levels in the serum were assessed on the 14th day after irradiation. The combined administration of SNP, WR-2721, rhIL-11 and rhG-CSF exerted synergistic recovery effects on peripheral blood WBC, RBC and platelet counts and hemoglobin levels in irradiated mice, and synergistic promotion effects on spleen, thymus, testicle, bone marrow nucleated cells and sperm counts in irradiated mice. The synergistic administration increased the serum SOD activities and serum testosterone content of irradiated mice, but synergy decreased the content of serum MDA and estradiol in irradiated mice. These results suggest that the combined administration of SNP, WR-2721, rhIL-11 and rhG-CSF should increase the efficacy of these drugs for acute radiation sickness, protect immunity, hematopoiesis and the reproductive organs of irradiated-damaged mice, and improve oxidation resistance in the body. (author)

2 x 2 TeV mu(superscript +) mu (superscript) collider

International Nuclear Information System (INIS)

Mokhov, N.V.; Noble, R.J.

1996-10-01

The scenarios for high-luminosity 2 x 2 TeV and 250 x 250 GeV μ + μ - colliders are presented. Having a high physics potential, such a machine has specific physics and technical advantages and disadvantages when compared with an e + e - collider. Parameters for the candidate designs and the basic components - proton source, pion production and decay channel, cooling, acceleration and collider storage ring - are considered. Attention is paid to the areas mostly affecting the collider performance: targetry, energy spread, superconducting magnet survival, detector backgrounds, polarization, environmental issues. 13 refs., 9 figs., 4 tabs

Academic Training: Physics at e+e- linear collider

CERN Multimedia

Françoise Benz

2004-01-01

15, 16, 17, 18, 19 November 2004-2005 ACADEMIC TRAINING PROGRAMME LECTURE SERIES from 11.00 to 12.00hrs - Main Auditorium, bldg. 500 Physics at e+e- linear collider K. DESCH / Desy, Hamburg, D Future e+e- Linear Colliders offer the potential to explore new physics at the TeV scale to very high precision. The lecture series introduces the possibilities of a TeV linear collider (the International Linear Collider, ILC) in the fields of Higgs physics, alternative Electro-weak Symmetry Breaking scenarios, Supersymmetry, Extra Dimensions, and more exotic models. Also the prospects for highly improved measurements of SM parameters such as the top quark mass and electro-weak gauge boson properties are discussed. The implications for the design of an appropriate detector are outlined and current R&D developments are explained. Particular emphasis will be given to the complementarity and intimate interplay of physics at the LHC and the ILC. The additional benefit of multi-TeV e+e- collisions as envisaged i...

Physics goals of the next linear collider

Energy Technology Data Exchange (ETDEWEB)

Kuhlman, S. [Argonne National Lab., IL (United States); Marciano, W.J. [Brookhaven National Lab., Upton, NY (United States); Gunion, J. F. [California Univ., Davis, CA (United States)] [and others; NLC ZDR Design Group; NLC Physics Working Group

1996-05-01

We present the prospects for the next generation of high-energy physics experiments with electron-positron colliding beams. This report summarizes the current status of the design and technological basis of a linear collider of center of mass energy 500 GeV-1.5 TeV, and the opportunities for high-energy physics experiments that this machine is expected to open. 132 refs., 54 figs., 14 tabs.

Physics goals of the next linear collider

International Nuclear Information System (INIS)

Kuhlman, S.; Marciano, W.J.; Gunion, J. F.

1996-05-01

We present the prospects for the next generation of high-energy physics experiments with electron-positron colliding beams. This report summarizes the current status of the design and technological basis of a linear collider of center of mass energy 500 GeV-1.5 TeV, and the opportunities for high-energy physics experiments that this machine is expected to open. 132 refs., 54 figs., 14 tabs

Physics possibilities of lepton and hadron colliders

International Nuclear Information System (INIS)

Peccei, R.D.

1985-05-01

After a brief introduction to lepton and hadron colliders presently being planned, I give some examples of the nice standard physics which is expected to be seen in them. The bulk of the discussion, however, is centered on signals for new physics. Higgs searches at the new colliders are discussed, as well as signatures and prospects for detecting effects of supersymmetry, compositeness and dynamical symmetry breakdown. (orig.)

The Compact Muon Solenoid Experiment at the Large Hadron Collider The Compact Muon Solenoid Experiment at the Large Hadron Collider

Directory of Open Access Journals (Sweden)

David Delepine

2012-02-01

Full Text Available The Compact Muon Solenoid experiment at the CERN Large Hadron Collider will study protonproton collisions at unprecedented energies and luminosities. In this article we providefi rst a brief general introduction to particle physics. We then explain what CERN is. Thenwe describe the Large Hadron Collider at CERN, the most powerful particle acceleratorever built. Finally we describe the Compact Muon Solenoid experiment, its physics goals,construction details, and current status.El experimento Compact Muon Solenoid en el Large Hadron Collider del CERN estudiarácolisiones protón protón a energías y luminosidades sin precedente. En este artículo presentamos primero una breve introducción general a la física de partículas. Despuésexplicamos lo que es el CERN. Luego describimos el Large Hadron Collider, el más potente acelerador de partículas construido por el hombre, en el CERN. Finalmente describimos el experimento Compact Muon Solenoid, sus objetivos en física, los detalles de su construcción,y su situación presente.

Muon-muon and other high energy colliders

International Nuclear Information System (INIS)

Palmer, R.B.; Gallardo, J.C.

1997-02-01

The first section looks at the high energy physics advantages, disadvantages and luminosity requirements of hadron, of lepton and photon-photon colliders for comparison. The second section discusses the physics considerations for the muon collider. The third section covers muon collider components. The fourth section is about the intersection region and detectors. In the fifth section, the authors discuss modifications to enhance the muon polarization's operating parameters with very small momentum spreads, operations at energies other than the maximum for which the machine is designed, and designs of machines for different maximum energies. The final section discusses a Research and Development plan aimed at the operation of a 0.5 TeV demonstration machine by the year 2010, and of the 4 TeV machine by the year 2020

Collider and Detector Protection at Beam Accidents

Science.gov (United States)

Rakhno, I. L.; Mokhov, N. V.; Drozhdin, A. I.

2003-12-01

Dealing with beam loss due to abort kicker prefire is considered for hadron colliders. The prefires occured at Tevatron (Fermilab) during Run I and Run II are analyzed and a protection system implemented is described. The effect of accidental beam loss in the Large Hadron Collider (LHC) at CERN on machine and detector components is studied via realistic Monte Carlo calculations. The simulations show that beam loss at an unsynchronized beam abort would result in severe heating of conventional and superconducting magnets and possible damage to the collider detector elements. A proposed set of collimators would reduce energy deposition effects to acceptable levels. Special attention is paid to reducing peak temperature rise within the septum magnet and minimizing quench region length downstream of the LHC beam abort straight section.

Collider and Detector Protection at Beam Accidents

International Nuclear Information System (INIS)

Rakhno, I.L.; Mokhov, N.V.; Drozhdin, A.I.

2003-01-01

Dealing with beam loss due to abort kicker prefire is considered for hadron colliders. The prefires occurred at Tevatron (Fermilab) during Run I and Run II are analyzed and a protection system implemented is described. The effect of accidental beam loss in the Large Hadron Collider (LHC) at CERN on machine and detector components is studied via realistic Monte Carlo calculations. The simulations show that beam loss at an unsynchronized beam abort would result in severe heating of conventional and superconducting magnets and possible damage to the collider detector elements. A proposed set of collimators would reduce energy deposition effects to acceptable levels. Special attention is paid to reducing peak temperature rise within the septum magnet and minimizing quench region length downstream of the LHC beam abort straight section

Collider and detector protection at beam accidents

International Nuclear Information System (INIS)

Rakhno, I.L.; Mokhov, N.V.; Drozhdin, A.I.

2003-01-01

Dealing with beam loss due to abort kicker prefire is considered for hadron colliders. The prefires occurred at Tevatron (Fermilab) during Run I and Run II are analyzed and a protection system implemented is described. The effect of accidental beam loss in the Large Hadron Collider (LHC) at CERN on machine and detector components is studied via realistic Monte Carlo calculations. The simulations show that beam loss at an unsynchronized beam abort would result in severe heating of conventional and superconducting magnets and possible damage to the collider detector elements. A proposed set of collimators would reduce energy deposition effects to acceptable levels. Special attention is paid to reducing peak temperature rise within the septum magnet and minimizing quench region length downstream of the LHC beam abort straight section

Large Hadron Collider manual

CERN Document Server

Lavender, Gemma

2018-01-01

What is the universe made of? How did it start? This Manual tells the story of how physicists are seeking answers to these questions using the world’s largest particle smasher – the Large Hadron Collider – at the CERN laboratory on the Franco-Swiss border. Beginning with the first tentative steps taken to build the machine, the digestible text, supported by color photographs of the hardware involved, along with annotated schematic diagrams of the physics experiments, covers the particle accelerator’s greatest discoveries – from both the perspective of the writer and the scientists who work there. The Large Hadron Collider Manual is a full, comprehensive guide to the most famous, record-breaking physics experiment in the world, which continues to capture the public imagination as it provides new insight into the fundamental laws of nature.

CERN: TeV Electron-Positron Linear Collider Studies; More polarization in LEP

Energy Technology Data Exchange (ETDEWEB)

Anon.

1993-09-15

The world's highest energy electronpositron collider - CERN's LEP, with a circumference of 27 kilometres - will also be the last such machine to be built as a storage ring. With interest growing in electronpositron physics at energies beyond those attainable at LEP, the next generation of electron-positron colliders must be linear if prohibitive synchrotron radiation power losses are to be avoided. Very high energy linear colliders present many technical challenges but mastery of SLC at Stanford, the world's first electron-positron linear collider, is encouraging. The physics issues of a linear collider have been examined by the international community in ICFA workshops in Saariselka, Finland (September 1991) and most recently in Hawaii (April 1993). The emerging consensus is for a collider with an initial collision energy around 500 GeV, and which can be upgraded to over 1 TeV. A range of very different collider designs are being studied at Laboratories in Europe, the US, Japan and Russia. Following the report of the 1987 CERN Long Range Planning Committee chaired by Carlo Rubbia, studies for a 2 TeV linear collider have progressed at CERN alongside work towards the Laboratory's initial objective - the LHC high energy proton-proton collider in the LEP tunnel.

CERN: TeV Electron-Positron Linear Collider Studies; More polarization in LEP

International Nuclear Information System (INIS)

Anon.

1993-01-01

The world's highest energy electronpositron collider - CERN's LEP, with a circumference of 27 kilometres - will also be the last such machine to be built as a storage ring. With interest growing in electronpositron physics at energies beyond those attainable at LEP, the next generation of electron-positron colliders must be linear if prohibitive synchrotron radiation power losses are to be avoided. Very high energy linear colliders present many technical challenges but mastery of SLC at Stanford, the world's first electron-positron linear collider, is encouraging. The physics issues of a linear collider have been examined by the international community in ICFA workshops in Saariselka, Finland (September 1991) and most recently in Hawaii (April 1993). The emerging consensus is for a collider with an initial collision energy around 500 GeV, and which can be upgraded to over 1 TeV. A range of very different collider designs are being studied at Laboratories in Europe, the US, Japan and Russia. Following the report of the 1987 CERN Long Range Planning Committee chaired by Carlo Rubbia, studies for a 2 TeV linear collider have progressed at CERN alongside work towards the Laboratory's initial objective - the LHC high energy proton-proton collider in the LEP tunnel

X-ray emission due to interaction of SN1987A ejecta with its progenitor's stellar-wind matter

International Nuclear Information System (INIS)

Masai, Kuniaki.

1990-06-01

The progenitor of the supernova 1987A, Sk-69 202 probably had lost a considerable amount of mass in its stellar wind in the past evolutionary track through a red supergiant to a blue supergiant. In about 10 years, the expanding ejecta of SN1987A will catch up to collide with the wind matter ejected in the red supergiant phase. Shocks due to the collision will heat up the ejecta and the wind matter to cause an enhancement of thermal X-ray emission lasting for several decades. We predict the X-ray light curve and the spectrum as well as the epoch of the enhancement intending to encourage future X-ray observations, which will give a clue for the study of such peculiar stellar evolution with a blueward transition as Sk-69 202. (author)

Proceedings of the workshop on the PS-spin collider

International Nuclear Information System (INIS)

Mori, Yoshiharu

1993-05-01

This volume is a record of the PS-Spin Collider Workshop which was held at KEK, Jan. 31-Feb.1, 1992. As a future project of the KEK 12-GeV proton synchrotron (KEK-PS), the hadron collider (PS-Collider), has been under discussion. Originally, the PSC was designed for heavy ion beam collisions with the energy range of 5-7 GeV/u. If polarized protons are accelerated in PSC, 19 x 19 GeV collisions are possible. This workshop was proposed to bring together interested experimentalists and accelerator physicists to discuss the case that could be made for polarization physics and the technical feasibility at the PS Spin Collider. More than 30 physicists participated in the workshop and very interesting and useful discussions took place. (author)

Hadron collider physics

Energy Technology Data Exchange (ETDEWEB)

Pondrom, L.

1991-10-03

An introduction to the techniques of analysis of hadron collider events is presented in the context of the quark-parton model. Production and decay of W and Z intermediate vector bosons are used as examples. The structure of the Electroweak theory is outlined. Three simple FORTRAN programs are introduced, to illustrate Monte Carlo calculation techniques. 25 refs.

Hadron collider physics

International Nuclear Information System (INIS)

Pondrom, L.

1991-01-01

An introduction to the techniques of analysis of hadron collider events is presented in the context of the quark-parton model. Production and decay of W and Z intermediate vector bosons are used as examples. The structure of the Electroweak theory is outlined. Three simple FORTRAN programs are introduced, to illustrate Monte Carlo calculation techniques. 25 refs

Top quark studies at hadron colliders

Energy Technology Data Exchange (ETDEWEB)

Sinervo, P.K. [Univ. of Toronto, Ontario (Canada)

1997-01-01

The techniques used to study top quarks at hadron colliders are presented. The analyses that discovered the top quark are described, with emphasis on the techniques used to tag b quark jets in candidate events. The most recent measurements of top quark properties by the CDF and DO Collaborations are reviewed, including the top quark cross section, mass, branching fractions, and production properties. Future top quark studies at hadron colliders are discussed, and predictions for event yields and uncertainties in the measurements of top quark properties are presented.

Top quark studies at hadron colliders

International Nuclear Information System (INIS)

Sinervo, P.K.

1997-01-01

The techniques used to study top quarks at hadron colliders are presented. The analyses that discovered the top quark are described, with emphasis on the techniques used to tag b quark jets in candidate events. The most recent measurements of top quark properties by the CDF and DO Collaborations are reviewed, including the top quark cross section, mass, branching fractions, and production properties. Future top quark studies at hadron colliders are discussed, and predictions for event yields and uncertainties in the measurements of top quark properties are presented

Top quark studies at hadron colliders

International Nuclear Information System (INIS)

Sinervo, P.K.

1996-08-01

The techniques used to study top quarks at hadron colliders are presented. The analyses that discovered the top quark are described, with emphasis on the techniques used to tag b quark jets in candidate events. The most recent measurements of top quark properties by the CDF and D null collaborations are reviewed, including the top quark cross section, mass, branching fractions and production properties. Future top quark studies at hadron colliders are discussed, and predictions for event yields and uncertainties in the measurements of top quark properties are presented

Physics and planning for future colliders

International Nuclear Information System (INIS)

Kane, G.L.

1985-01-01

Physics opportunities at future (not presently under construction) colliders are examined, particularly with reference to the motivations for building them. First a number of considerations involved in planning and choosing beams, energies, and luminosities are discussed. Higgs physics, which currently seems to be the central problem of particle physics, is emphasized, with detailed study of how to do WW scattering and how to detect effects of heavy Higgs bosons. Some new results are included. High energy hadron colliders dominate the discussion, but alternatives are examined for comparison and when they have unique capabilities

The lay-out of the photon collider at the international linear collider

Indian Academy of Sciences (India)

6. — journal of. December 2007 physics pp. 1177–1179. The lay-out of the photon collider ... the sum of the disruption angle and the angular size of the final quad. ... will be less precise and it can affect the quality of some physics results.

Future Linear Colliders: Detector R&D, Jet Reconstruction and Top Physics Potential

CERN Document Server

AUTHOR|(CDS)2098729; Ros Martinez, Eduardo

During the 20th century, discoveries and measurements at colliders, combined with progress in theoretical physics, allowed us to formulate the Standard Model of the in- teractions between the constituents of matter. Today, there are two advanced projects for a new installation that will collide electrons and positrons covering an energy range from several hundreds of GeV to the multi-TeV scale, the International Linear Collider (ILC) and the Compact Linear Collider (CLIC). These Future Linear Colliders give the opportunity to study the top quark with unprecedented precision. Measurements of top quark properties are of special interest, as the top quark is the heaviest ele- mentary particle of the SM. Precision measurements of top quark properties at e+e colliders promise therefore to be highly sensitive to physics beyond the SM. This thesis has three complementary parts. The first is dedicated to the R&D of the ILD detector concept for future e+e- colliders, more precisely, the innermost region of the de...

A spectroscopic search for colliding stellar winds in O-type close binary systems. IV - Iota Orionis

Science.gov (United States)

Gies, Douglas R.; Wiggs, Michael S.; Bagnuolo, William G., Jr.

1993-01-01

We present H-alpha and He I 6678 A line profiles for the eccentric orbit binary Iota Ori. We have applied a tomography algorithm which uses the established orbital velocity curves and intensity ratio to reconstruct the spectral line profiles for each star. The He I profiles appear as pure photospheric lines, and H-alpha shows variable emission in the line core throughout the orbit (which is typical of O giants) and in the blue wing near periastron passage. We show that the blue wing emission is consistent with an origin between the stars which probably results from a dramatic focusing of the primary's stellar wind at periastron. We also present IUE archival spectra of the UV wind lines N V 1240 A and C IV 1550 A.

The Tevatron Hadron Collider: A short history

International Nuclear Information System (INIS)

Tollestrup, A.V.

1994-11-01

The subject of this presentation was intended to cover the history of hadron colliders. However this broad topic is probably better left to historians. I will cover a much smaller portion of this subject and specialize my subject to the history of the Tevatron. As we will see, the Tevatron project is tightly entwined with the progress in collider technology. It occupies a unique place among accelerators in that it was the first to make use of superconducting magnets and indeed the basic design now forms a template for all machines using this technology. It was spawned in an incredibly productive era when new ideas were being generated almost monthly and it has matured into our highest energy collider complete with two large detectors that provide the major facility in the US for probing high Pt physics for the coming decade

ACADEMIC TRAINING Progress on e+e- Linear Colliders

CERN Multimedia

Françoise Benz

2002-01-01

27, 28, 29, 30, 31 May LECTURE SERIES from 11.00 to 12.00 hrs - Auditorium, bldg. 500 Progress on e+e- Linear Colliders by P. Zerwas / Desy, D and R. Siemann / Slac, USA Physics issues (P. Zerwas - 27, 28 May)The physics program will be reviewed for e+e- linear colliders in the TeV energy range. At these prospective facilities central issues of particle physics can be addressed, the problem of mass, unification and structure of space-time. In this context the two lectures will focus on analyses of the Higgs mechanism, supersymmetry and extra space dimensions. Moreover, high-precision studies of the top-quark and the gauge boson sector will be discussed. Combined with LHC results, a comprehensive picture can be developed of physics at the electroweak scale and beyond. Designs and technologies (R. Siemann - 29, 30, 31 May) The physics and technologies of high energy linear colliders will be reviewed. Fundamental concepts of linear colliders will be introduced. They will be discussed in: the context of the Sta...

Neutrino physics at a muon collider

International Nuclear Information System (INIS)

King, B.J.

1998-02-01

This paper gives an overview of the neutrino physics possibilities at a future muon storage ring, which can be either a muon collider ring or a ring dedicated to neutrino physics that uses muon collider technology to store large muon currents. After a general characterization of the neutrino beam and its interactions, some crude quantitative estimates are given for the physics performance of a muon ring neutrino experiment (MURINE) consisting of a high rate, high performance neutrino detector at a 250 GeV muon collider storage ring. The paper is organized as follows. The next section describes neutrino production from a muon storage rings and gives expressions for event rates in general purpose and long baseline detectors. This is followed by a section outlining a serious design constraint for muon storage rings: the need to limit the radiation levels produced by the neutrino beam. The following two sections describe a general purpose detector and the experimental reconstruction of interactions in the neutrino target then, finally, the physics capabilities of a MURINE are surveyed

Linear collider applications of superconducting RF

International Nuclear Information System (INIS)

Rubin, D.L.

1990-01-01

The most promising technology for producing interactions of electrons and positrons in TeV energy range is the linear collider. In the linear collider each and every collision of charged particles depends on the production of the charges at rest and then the acceleration of those charges to full energy. The particles that exit the interaction region are discharded. A consequence of this mode of operation is that the luminosity of the machine is ultimately determined by the efficiency with which AC power can be converted into beam power. The consideration of superconducting cavities is motivated by the need for high efficiency. Thus, the high emittance around a beam collider and low emittance around beams are discussed first in the present report. Flat beams are then addressed focusing on the characteristics of the source, final focus, and beam stability. The beam stability, in particular, is discussed in detail in relation to the multiple bunch transverse stability, wake field induced energy spread, trapped modes, pulse width, duty cycle, RF power, and refrigerator power. (N.K.)

The Antiproton-Ion-Collider at FAIR

International Nuclear Information System (INIS)

Kruecken, R.; Fabbietti, L.; Faestemann, T.; Homolka, J.; Kienle, P.; Ring, P.; Suzuki, K.; Bosch, F.; Franzke, B.; Kozhuharov, Ch.; Litvinov, Y.; Nolden, F.; Cargnelli, M.; Fuhrmann, H.; Hirtl, A.; Marton, J.; Widmann, E.; Zmeskal, J.; Hayano, R. S.; Lenske, H.

2006-01-01

An antiproton-ion collider (AIC) has been proposed for the FAIR Project at Darmstadt to independently determine rms radii for protons and neutrons in stable and short lived nuclei by means of antiproton annihilation at medium energies. The AIC makes use of the ELISe electron ion collider complex to store, cool and collide antiprotons of 30 MeV energy with short lived radioactive ions in the NESR. The exotic nuclei are produced by projectile fragmentation or projectile fission and separated in the Super FRS. By detecting the loss of stored ions using the Schottky method the total absorption cross-section for antiprotons on the stored ions with mass A will be measured. Cross sections for the absorption on protons and neutrons, respectively, will be measured by the detection of residual nuclei with A-1 either by the Schottky method or by detecting them in recoil detectors after the first dipole stage of the NESR following the interaction zone. The absorption cross sections are in first order directly proportional to the mean square radii

SLAC R and D toward a TeV Linear Collider

International Nuclear Information System (INIS)

Wilson, P.B.

1988-10-01

At CERN, KEK, Novosibirsk and SLAC, serious thought is being given to the design of linear colliders in the 0.5--2.0 TeV center-of-mass energy range. This paper reviews current progress at SLAC toward the design of such a collider. No attempt is made here to summarize ongoing work at the other laboratories. However, research on linear colliders is clearly an international effort, and success at SLAC will be greatly expedited by communication and cooperation with other laboratories in the US and abroad. In addition to major programs at the laboratories mentioned above, contributions relevant to linear collider design are being made at DESY, LAL (Orsay), LBL, LLNL and elsewhere. 49 refs., 6 tabs

Accelerator physics and technology challenges of very high energy hadron colliders

Science.gov (United States)

Shiltsev, Vladimir D.

2015-08-01

High energy hadron colliders have been in the forefront of particle physics for more than three decades. At present, international particle physics community considers several options for a 100 TeV proton-proton collider as a possible post-LHC energy frontier facility. The method of colliding beams has not fully exhausted its potential but has slowed down considerably in its progress. This paper briefly reviews the accelerator physics and technology challenges of the future very high energy colliders and outlines the areas of required research and development towards their technical and financial feasibility.

Indirect probe of electroweak-interacting particles at future lepton colliders

International Nuclear Information System (INIS)

Harigaya, Keisuke; Ichikawa, Koji; Kundu, Anirban; Matsumoto, Shigeki; Shirai, Satoshi

2015-01-01

Various types of electroweak-interacting particles, which have non-trivial charges under the SU(2)_L×U(1)_Y gauge symmetry, appear in various extensions of the Standard Model. These particles are good targets of future lepton colliders, such as the International Linear Collider (ILC), the Compact LInear Collider (CLIC) and the Future Circular Collider of electrons and positrons (FCC-ee). An advantage of the experiments is that, even if their beam energies are below the threshold of the production of the new particles, quantum effects of the particles can be detected through high precision measurements. We estimate the capability of future lepton colliders to probe electroweak-interacting particles through the quantum effects, with particular focus on the wino, the Higgsino and the so-called minimal dark matters, and found that a particle whose mass is greater than the beam energy by 100–1000 GeV is detectable by measuring di-fermion production cross sections with O(0.1)% accuracy. In addition, with the use of the same analysis, we also discuss the sensitivity of the future colliders to model independent higher dimensional operators, and found that the cutoff scales corresponding to the operators can be probed up to a few ten TeV.

Status of muon collider research and development and future plans

Directory of Open Access Journals (Sweden)

1999-08-01

Full Text Available The status of the research on muon colliders is discussed and plans are outlined for future theoretical and experimental studies. Besides work on the parameters of a 3–4 and 0.5 TeV center-of-mass (COM energy collider, many studies are now concentrating on a machine near 0.1 TeV (COM that could be a factory for the s-channel production of Higgs particles. We discuss the research on the various components in such muon colliders, starting from the proton accelerator needed to generate pions from a heavy-Z target and proceeding through the phase rotation and decay (π→μν_{μ} channel, muon cooling, acceleration, storage in a collider ring, and the collider detector. We also present theoretical and experimental R&D plans for the next several years that should lead to a better understanding of the design and feasibility issues for all of the components. This report is an update of the progress on the research and development since the feasibility study of muon colliders presented at the Snowmass '96 Workshop [R. B. Palmer, A. Sessler, and A. Tollestrup, Proceedings of the 1996 DPF/DPB Summer Study on High-Energy Physics (Stanford Linear Accelerator Center, Menlo Park, CA, 1997].

Indirect Probe of Electroweak-Interacting Particles at Future Lepton Colliders

International Nuclear Information System (INIS)

Harigaya, Keisuke

2015-04-01

Various types of electroweak-interacting particles, which have non-trivial charges under the SU(2) L x U(1) Y gauge symmetry, appear in various extensions of the Standard Model. These particles are good targets of future lepton colliders, such as the International Linear Collider (ILC), the Compact LInear Collider (CLIC) and the Future Circular Collider of electrons and positrons (FCC-ee). An advantage of the experiments is that, even if their beam energies are below the threshold of the production of the new particles, quantum effects of the particles can be detected through high precision measurements. We estimate the capability of future lepton colliders to probe electroweak-interacting particles through the quantum effects, with particular focus on the wino, the Higgsino and the so-called minimal dark matters, and found that a particle whose mass is greater than the beam energy by 100-1000 GeV is detectable by measuring di-fermion production cross sections with O(0.1)% accuracy. In addition, with the use of the same analysis, we also discuss the sensitivity of the future colliders to model independent higher dimensional operators, and found that the cutoff scales corresponding to the operators can be probed up to a few ten TeV.

LINEAR COLLIDERS: 1992 workshop

International Nuclear Information System (INIS)

Settles, Ron; Coignet, Guy

1992-01-01

As work on designs for future electron-positron linear colliders pushes ahead at major Laboratories throughout the world in a major international collaboration framework, the LC92 workshop held in Garmisch Partenkirchen this summer, attended by 200 machine and particle physicists, provided a timely focus

Review of linear colliders

International Nuclear Information System (INIS)

Takeda, Seishi

1992-01-01

The status of R and D of future e + e - linear colliders proposed by the institutions throughout the world is described including the JLC, NLC, VLEPP, CLIC, DESY/THD and TESLA projects. The parameters and RF sources are discussed. (G.P.) 36 refs.; 1 tab

Crabbing system for an electron-ion collider

Energy Technology Data Exchange (ETDEWEB)

Castilla, Alejandro [Old Dominion Univ., Norfolk, VA (United States)

2017-05-01

As high energy and nuclear physicists continue to push further the boundaries of knowledge using colliders, there is an imperative need, not only to increase the colliding beams' energies, but also to improve the accuracy of the experiments, and to collect a large quantity of events with good statistical sensitivity. To achieve the latter, it is necessary to collect more data by increasing the rate at which these processes are being produced and detected in the machine. This rate of events depends directly on the machine's luminosity. The luminosity itself is proportional to the frequency at which the beams are being delivered, the number of particles in each beam, and inversely proportional to the cross-sectional size of the colliding beams. There are several approaches that can be considered to increase the events statistics in a collider other than increasing the luminosity, such as running the experiments for a longer time. However, this also elevates the operation expenses, while increasing the frequency at which the beams are delivered implies strong physical changes along the accelerator and the detectors. Therefore, it is preferred to increase the beam intensities and reduce the beams cross-sectional areas to achieve these higher luminosities. In the case where the goal is to push the limits, sometimes even beyond the machines design parameters, one must develop a detailed High Luminosity Scheme. Any high luminosity scheme on a modern collider considers|in one of their versions|the use of crab cavities to correct the geometrical reduction of the luminosity due to the beams crossing angle. In this dissertation, we present the design and testing of a proof-of-principle compact superconducting crab cavity, at 750 MHz, for the future electron-ion collider, currently under design at Jefferson Lab. In addition to the design and validation of the cavity prototype, we present the analysis of the first order beam dynamics and the integration of the

Physics and Analysis at a Hadron Collider - An Introduction (1/3)

CERN Multimedia

CERN. Geneva

2010-01-01

This is the first lecture of three which together discuss the physics of hadron colliders with an emphasis on experimental techniques used for data analysis. This first lecture provides a brief introduction to hadron collider physics and collider detector experiments as well as offers some analysis guidelines. The lectures are aimed at graduate students.

Polarized proton collider at RHIC

International Nuclear Information System (INIS)

Alekseev, I.; Allgower, C.; Bai, M.; Batygin, Y.; Bozano, L.; Brown, K.; Bunce, G.; Cameron, P.; Courant, E.; Erin, S.; Escallier, J.; Fischer, W.; Gupta, R.; Hatanaka, K.; Huang, H.; Imai, K.; Ishihara, M.; Jain, A.; Lehrach, A.; Kanavets, V.; Katayama, T.; Kawaguchi, T.; Kelly, E.; Kurita, K.; Lee, S.Y.; Luccio, A.; MacKay, W.W.; Mahler, G.; Makdisi, Y.; Mariam, F.; McGahern, W.; Morgan, G.; Muratore, J.; Okamura, M.; Peggs, S.; Pilat, F.; Ptitsin, V.; Ratner, L.; Roser, T.; Saito, N.; Satoh, H.; Shatunov, Y.; Spinka, H.; Syphers, M.; Tepikian, S.; Tominaka, T.; Tsoupas, N.; Underwood, D.; Vasiliev, A.; Wanderer, P.; Willen, E.; Wu, H.; Yokosawa, A.; Zelenski, A.N.

2003-01-01

In addition to heavy ion collisions (RHIC Design Manual, Brookhaven National Laboratory), RHIC will also collide intense beams of polarized protons (I. Alekseev, et al., Design Manual Polarized Proton Collider at RHIC, Brookhaven National Laboratory, 1998, reaching transverse energies where the protons scatter as beams of polarized quarks and gluons. The study of high energy polarized protons beams has been a long term part of the program at BNL with the development of polarized beams in the Booster and AGS rings for fixed target experiments. We have extended this capability to the RHIC machine. In this paper we describe the design and methods for achieving collisions of both longitudinal and transverse polarized protons in RHIC at energies up to √s=500 GeV

Conventional power sources for colliders

International Nuclear Information System (INIS)

Allen, M.A.

1987-07-01

At SLAC we are developing high peak-power klystrons to explore the limits of use of conventional power sources in future linear colliders. In an experimental tube we have achieved 150 MW at 1 μsec pulse width at 2856 MHz. In production tubes for SLAC Linear Collider (SLC) we routinely achieve 67 MW at 3.5 μsec pulse width and 180 pps. Over 200 of the klystrons are in routine operation in SLC. An experimental klystron at 8.568 GHz is presently under construction with a design objective of 30 MW at 1 μsec. A program is starting on the relativistic klystron whose performance will be analyzed in the exploration of the limits of klystrons at very short pulse widths

Crab cavities for linear colliders

CERN Document Server

Burt, G; Carter, R; Dexter, A; Tahir, I; Beard, C; Dykes, M; Goudket, P; Kalinin, A; Ma, L; McIntosh, P; Shulte, D; Jones, Roger M; Bellantoni, L; Chase, B; Church, M; Khabouline, T; Latina, A; Adolphsen, C; Li, Z; Seryi, Andrei; Xiao, L

2008-01-01

Crab cavities have been proposed for a wide number of accelerators and interest in crab cavities has recently increased after the successful operation of a pair of crab cavities in KEK-B. In particular crab cavities are required for both the ILC and CLIC linear colliders for bunch alignment. Consideration of bunch structure and size constraints favour a 3.9 GHz superconducting, multi-cell cavity as the solution for ILC, whilst bunch structure and beam-loading considerations suggest an X-band copper travelling wave structure for CLIC. These two cavity solutions are very different in design but share complex design issues. Phase stabilisation, beam loading, wakefields and mode damping are fundamental issues for these crab cavities. Requirements and potential design solutions will be discussed for both colliders.

Final muon cooling for a muon collider

Science.gov (United States)

Acosta Castillo, John Gabriel

To explore the new energy frontier, a new generation of particle accelerators is needed. Muon colliders are a promising alternative if muon cooling can be made to work. Muons are 200 times heavier than electrons, so they produce less synchrotron radiation, and they behave like point particles. However, they have a short lifetime of 2.2 mus and the beam is more difficult to cool than an electron beam. The Muon Accelerator Program (MAP) was created to develop concepts and technologies required by a muon collider. An important effort has been made in the program to design and optimize a muon beam cooling system. The goal is to achieve the small beam emittance required by a muon collider. This work explores a final ionization cooling system using magnetic quadrupole lattices with a low enough beta* region to cool the beam to the required limit with available low Z absorbers.

Seismic studies for Fermilab future collider projects

International Nuclear Information System (INIS)

Lauh, J.; Shiltsev, V.

1997-11-01

Ground motion can cause significant beam emittance growth and orbit oscillations in large hadron colliders due to a vibration of numerous focusing magnets. Larger accelerator ring circumference leads to smaller revolution frequency and, e.g. for the Fermilab Very Large Hadron Collider(VLHC) 50-150 Hz vibrations are of particular interest as they are resonant with the beam betatron frequency. Seismic measurements at an existing large accelerator under operation can help to estimate the vibrations generated by the technical systems in future machines. Comparison of noisy and quiet microseismic conditions might be useful for proper choice of technical solutions for future colliders. This article presents results of wide-band seismic measurements at the Fermilab site, namely, in the tunnel of the Tevatron and on the surface nearby, and in two deep tunnels in the Illinois dolomite which is though to be a possible geological environment of the future accelerators

High luminosity particle colliders

International Nuclear Information System (INIS)

Palmer, R.B.; Gallardo, J.C.

1997-03-01

The authors consider the high energy physics advantages, disadvantages and luminosity requirements of hadron (pp, p anti p), lepton (e + e - , μ + μ - ) and photon-photon colliders. Technical problems in obtaining increased energy in each type of machine are presented. The machines relative size are also discussed

Intense beams at the micron level for the Next Linear Collider

International Nuclear Information System (INIS)

Seeman, J.T.

1991-08-01

High brightness beams with sub-micron dimensions are needed to produce a high luminosity for electron-positron collisions in the Next Linear Collider (NLC). To generate these small beam sizes, a large number of issues dealing with intense beams have to be resolved. Over the past few years many have been successfully addressed but most need experimental verification. Some of these issues are beam dynamics, emittance control, instrumentation, collimation, and beam-beam interactions. Recently, the Stanford Linear Collider (SLC) has proven the viability of linear collider technology and is an excellent test facility for future linear collider studies

Corrections for hydrostatic atmospheric models: radii and effective temperatures of Wolf Rayet stars

International Nuclear Information System (INIS)

Loore, C. de; Hellings, P.; Lamers, H.J.G.L.M.

1982-01-01

With the assumption of plane-parallel hydrostatic atmospheres, used generally for the computation of evolutionary models, the radii of WR stars are seriously underestimated. The true atmospheres may be very extended, due to the effect of the stellar wind. Instead of these hydrostatic atmospheres the authors consider dynamical atmospheres adopting a velocity law. The equation of the optical depth is integrated outwards using the equation of continuity. The ''hydrostatic'' radii are to be multiplied with a factor 2 to 8, and the effective temperatures with a factor 0.8 to 0.35 when Wolf Rayet characteristics for the wind are considered, and WR mass loss rates are used. With these corrections the effective temperatures of the theoretical models, which are helium burning Roche lobe overflow remnants, range between 30,000 K and 50,000 K. Effective temperatures calculated in the hydrostatic hypothesis can be as high as 150,000 K for helium burning RLOF-remnants with WR mass loss rates. (Auth.)

Physics at TeV e+e- linear colliders

International Nuclear Information System (INIS)

Chanowitz, M.S.

1992-01-01

A survey is presented of the physics opportunities at TeV e + e - linear colliders. Examples are given of physics that might emerge in e + e - collisions and in γγ collisions using the back-scattered laser technique, including γγ → ZZ scattering as a probe of ultraheavy quanta. The second portion of the talk focuses on physics that must emerge at or below the TeV scale--the mechanism of electroweak symmetry breaking. In particular a very rough estimate is presented of the most challenging possible signal of symmetry breaking, strong WW scattering, as a function of collider energy. A subtheme, made explicit in the concluding section, is the continuing complementarity of e + e - and pp colliders in the domain of TeV physics

Detectors for large e/sup +/e/sup -/ colliders

International Nuclear Information System (INIS)

Baltay, C.

1986-01-01

In this paper the author gives a brief review of the detectors now being built for the two new large e/sup +/e/sup -/ colliders, LEP, under construction at CERN, and the SLC, now under construction at SLAC. These colliders are intended to study the Z 0 energy region and above, with energies of around 100 to 200 GeV in the center of mass. The purpose of this paper is to list some of the physics topics of interest and given an indication of the requirements they make on the design of the detectors. It also contains a brief discussion giving some of the relevant parameters of the colliers, and gives a description of the large detectors now under construction to utilize these colliders

Top physics at high-energy lepton colliders. Summary

International Nuclear Information System (INIS)

Vos, M.

2016-04-01

A summary is presented of the workshop ''top physics at linear colliders'' that was held at IFIC Valencia from the 30"t"h of June to the 3"r"d July 2015. We present an up-to-date status report of studies into the potential for top quark physics of lepton colliders with an energy reach that exceeds the top quark pair production threshold, with a focus on the linear collider projects ILC and CLIC. This summary shows that such projects can offer very competitive determinations of top quark properties (mass, width) and its interactions with other Standard Model particles, in particular electroweak gauge bosons and the Higgs boson. In both areas the prospects exceed the LHC potential significantly - often by an order of magnitude.

Advances in beam physics and technology: Colliders of the future

Energy Technology Data Exchange (ETDEWEB)

Chattopadhyay, S.

1994-11-01

Beams may be viewed as directed and focussed flow of energy and information, carried by particles and electromagnetic radiation fields (ie, photons). Often, they interact with each other (eg, in high energy colliders) or with other forms of matter (eg, in fixed targets, sychrotron radiation, neutron scattering, laser chemistry/physics, medical therapy, etc.). The whole art and science of beams revolve around the fundamental quest for, and ultimate implementation of, mechanisms of production, storage, control and observation of beams -- always directed towards studies of the basic structures and processes of the natural world and various practical applications. Tremendous progress has been made in all aspects of beam physics and technology in the last decades -- nonlinear dynamics, superconducting magnets and rf cavities, beam instrumentation and control, novel concepts and collider praradigms, to name a few. We illustrate this progress with a few examples and remark on the emergence of new collider scenarios where some of these progress might come to use -- the Gamma-Gamma Collider, the Muon Collider, laser acceleration, etc. We close with an outline of future oppotunities and outlook.

Advances in beam physics and technology: Colliders of the future

International Nuclear Information System (INIS)

Chattopadhyay, S.

1994-11-01

Beams may be viewed as directed and focussed flow of energy and information, carried by particles and electromagnetic radiation fields (ie, photons). Often, they interact with each other (eg, in high energy colliders) or with other forms of matter (eg, in fixed targets, sychrotron radiation, neutron scattering, laser chemistry/physics, medical therapy, etc.). The whole art and science of beams revolve around the fundamental quest for, and ultimate implementation of, mechanisms of production, storage, control and observation of beams -- always directed towards studies of the basic structures and processes of the natural world and various practical applications. Tremendous progress has been made in all aspects of beam physics and technology in the last decades -- nonlinear dynamics, superconducting magnets and rf cavities, beam instrumentation and control, novel concepts and collider praradigms, to name a few. We illustrate this progress with a few examples and remark on the emergence of new collider scenarios where some of these progress might come to use -- the Gamma-Gamma Collider, the Muon Collider, laser acceleration, etc. We close with an outline of future oppotunities and outlook

Linear Collider Flavour Identification status report: Sensors for the ...

Indian Academy of Sciences (India)

The Linear Collider Flavour Identification (LCFI) collaboration is continuing the work to develop column-parallel CCDs (CPCCD) and CMOS readout chips to be used in the vertex detector at the international linear collider (ILC). The CPCCD achieves several orders of magnitude faster readout than conventional CCDs ...

Tolerable systematic errors in Really Large Hadron Collider dipoles

International Nuclear Information System (INIS)

Peggs, S.; Dell, F.

1996-01-01

Maximum allowable systematic harmonics for arc dipoles in a Really Large Hadron Collider are derived. The possibility of half cell lengths much greater than 100 meters is justified. A convenient analytical model evaluating horizontal tune shifts is developed, and tested against a sample high field collider

Final focus designs for crab waist colliders

Directory of Open Access Journals (Sweden)

A. Bogomyagkov

2016-12-01

Full Text Available The crab waist collision scheme promises significant luminosity gain. The successful upgrade of the DAΦNE collider proved the principle of crab waist collision and increased luminosity 3 times. Therefore, several new projects try to implement the scheme. The paper reviews interaction region designs with the crab waist collision scheme for already existent collider DAΦNE and SuperKEKB, presently undergoing commissioning, for the projects of SuperB in Italy, CTau in Novosibirsk and FCC-ee at CERN.

Classification of ISO SWS 01 spectra of proto-planetary nebulae: a search for precursors of planetary nebulae with [WR] central stars

OpenAIRE

Szczerba, R.; Stasi{ń}ska, G.; Siódmiak, N.; Górny, S. K.

2002-01-01

We have analyzed ISO SWS 01 observations for 61 proto-planetary nebulae candidates and classified their spectra according to their dominant chemistry. On the basis of our classification and the more general classification of SWS 01 spectra by Kraemer et al. (2002) we discuss the connection between proto-planetary nebulae candidates and planetary nebulae, with emphasis on possible precursors of planetary nebulae with [WR] central stars.

CD8 Knockout Mice Are Protected from Challenge by Vaccination with WR201, a Live Attenuated Mutant of Brucella melitensis

Directory of Open Access Journals (Sweden)

Samuel L. Yingst

2013-01-01

Full Text Available CD8+ T cells have been reported to play an important role in defense against B. abortus infection in mouse models. In the present report, we use CD8 knockout mice to further elucidate the role of these cells in protection from B. melitensis infection. Mice were immunized orally by administration of B. melitensis WR201, a purine auxotrophic attenuated vaccine strain, then challenged intranasally with B. melitensis 16M. In some experiments, persistence of WR201 in the spleens of CD8 knockout mice was slightly longer than that in the spleens of normal mice. However, development of anti-LPS serum antibody, antigen-induced production of γ-interferon (IFN-γ by immune splenic lymphocytes, protection against intranasal challenge, and recovery of nonimmunized animals from intranasal challenge were similar between normal and knockout animals. Further, primary Brucella infection was not exacerbated in perforin knockout and Fas-deficient mice and these animals’ anti-Brucella immune responses were indistinguishable from those of normal mice. These results indicate that CD8+ T cells do not play an essential role as either cytotoxic cells or IFN-γ producers, yet they do participate in a specific immune response to immunization and challenge in this murine model of B. melitensis infection.

CLIC: developing a linear collider

CERN Multimedia

Laurent Guiraud

1999-01-01

Compact Linear Collider (CLIC) is a CERN project to provide high-energy electron-positron collisions. Instead of conventional radio-frequency klystrons, CLIC will use a low-energy, high-intensity primary beam to produce acceleration.

Multiplicities and minijets at Tevatron Collider energies

International Nuclear Information System (INIS)

Sarcevic, I.

1989-01-01

We show that in the parton branching model, the probability distribution does not obey KNO scaling. As energy increases, gluon contribution to multiplicities increases, resulting in the widening of the probability distribution, in agreement with experimental data. We predict that the widening of the distribution will stop at Tevatron Collider energies due to the dominant role of gluons at these energies. We also find that the gluon contribution to the 'minijet' cross section increases with energy and becomes dominant at the Tevatron Collider. We calculate QCD minijet cross sections for a variety of structure functions, QCD scales and p T min . We compare our theoretical results with the experimental data and find that some of the structure functions and choices of scale are preferred by the experimental data. We give theoretical predictions for the minijet cross section at the Tevatron Collider, indicating the possibility of distinguishing between different sets of structure functions and choices of scale. (orig.)

Calorimetry for the Future Circular Collider experiments

CERN Document Server

AUTHOR|(INSPIRE)INSPIRE-00510572; Kisiel, Adam

2017-11-21

The Future Circular Collider (FCC) Collaboration is preparing the next generation of experiments in high energy physics. The goal is to collide protons at 100 TeV centre–of–mass energy, seven times higher than at the most powerful existing accelerator, the Large Hadron Collider (LHC). Such machine would extend the research carried out at the LHC including the study of the Higgs boson, the search for the origin of the baryon asymmetry, the mass of neutrinos, and the dark matter. The detectors designed for the FCC experiments need to tackle the harsh conditions of the unprecedented collision energy and luminosity. At the same time, they need to provide precise measurements in a wider range of pseudorapidity than the existing experiments. The focus of this thesis is a design and performance studies of one of the sub-detectors, the electromagnetic calorimeter. Its aim is to measure the energy and the position of electrons, positrons, and photons produced in the collisions. The detector proposed in this thesis...

Mighty Murines: Neutrino Physics at very high Energy Muon Colliders

International Nuclear Information System (INIS)

King, B.J.

2000-01-01

An overview is given of the potential for neutrino physics studies through parasitic use of the intense high energy neutrino beams that would be produced at future many-TeV muon colliders. Neutrino experiments clearly cannot compete with the collider physics. Except at the very highest energy muon colliders, the main thrust of the neutrino physics program would be to improve on the measurements from preceding neutrino experiments at lower energy muon colliders, particularly in the fields of B physics, quark mixing and CP violation. Muon colliders at the 10 TeV energy scale might already produce of order 10 8 B hadrons per year in a favorable and unique enough experimental environment to have some analytical capabilities beyond any of the currently operating or proposed B factories. The most important of the quark mixing measurements at these energies might well be the improved measurements of the important CKM matrix elements |V ub | and |V cb | and, possibly, the first measurements of |V td | in the process of flavor changing neutral current interactions involving a top quark loop. Muon colliders at the highest center-of-mass energies that have been conjectured, 100--1,000 TeV, would produce neutrino beams for neutrino-nucleon interaction experiments with maximum center-of-mass energies from 300--1,000 GeV. Such energies are close to, or beyond, the discovery reach of all colliders before the turn-on of the LHC. In particular, they are comparable to the 314 GeV center-of-mass energy for electron-proton scattering at the currently operating HERA collider and so HERA provides a convenient benchmark for the physics potential. It is shown that these ultimate terrestrial neutrino experiments, should they eventually come to pass, would have several orders of magnitude more luminosity than HERA. This would potentially open up the possibility for high statistics studies of any exotic particles, such as leptoquarks, that might have been previously discovered at these

German lab unveils plan to build physicists' next collider

CERN Multimedia

Abott, A

2001-01-01

An international team of physicists are to propose the construction of a major collider. 'TESLA' - the 'Tera electron volt Energy Superconducting Linear Accelerator' will be a linear electron-positron collider based on superconducting resonators. It will be based at DESY and cost around three billion US dollars (2 pages).

LINEAR COLLIDER PHYSICS RESOURCE BOOK FOR SNOWMASS 2001

International Nuclear Information System (INIS)

ABE, T.; DAWSON, S.; HEINEMEYER, S.; MARCIANO, W.; PAIGE, F.; TURCOT, A.S.; ET

2001-01-01

The American particle physics community can look forward to a well-conceived and vital program of experimentation for the next ten years, using both colliders and fixed target beams to study a wide variety of pressing questions. Beyond 2010, these programs will be reaching the end of their expected lives. The CERN LHC will provide an experimental program of the first importance. But beyond the LHC, the American community needs a coherent plan. The Snowmass 2001 Workshop and the deliberations of the HEPAP subpanel offer a rare opportunity to engage the full community in planning our future for the next decade or more. A major accelerator project requires a decade from the beginning of an engineering design to the receipt of the first data. So it is now time to decide whether to begin a new accelerator project that will operate in the years soon after 2010. We believe that the world high-energy physics community needs such a project. With the great promise of discovery in physics at the next energy scale, and with the opportunity for the uncovering of profound insights, we cannot allow our field to contract to a single experimental program at a single laboratory in the world. We believe that an e + e - linear collider is an excellent choice for the next major project in high-energy physics. Applying experimental techniques very different from those used at hadron colliders, an e + e - linear collider will allow us to build on the discoveries made at the Tevatron and the LHC, and to add a level of precision and clarity that will be necessary to understand the physics of the next energy scale. It is not necessary to anticipate specific results from the hadron collider programs to argue for constructing an e + e - linear collider; in any scenario that is now discussed, physics will benefit from the new information that e + e - experiments can provide

LINEAR COLLIDER PHYSICS RESOURCE BOOK FOR SNOWMASS 2001.

Energy Technology Data Exchange (ETDEWEB)

ABE,T.; DAWSON,S.; HEINEMEYER,S.; MARCIANO,W.; PAIGE,F.; TURCOT,A.S.; ET AL

2001-05-03

The American particle physics community can look forward to a well-conceived and vital program of experimentation for the next ten years, using both colliders and fixed target beams to study a wide variety of pressing questions. Beyond 2010, these programs will be reaching the end of their expected lives. The CERN LHC will provide an experimental program of the first importance. But beyond the LHC, the American community needs a coherent plan. The Snowmass 2001 Workshop and the deliberations of the HEPAP subpanel offer a rare opportunity to engage the full community in planning our future for the next decade or more. A major accelerator project requires a decade from the beginning of an engineering design to the receipt of the first data. So it is now time to decide whether to begin a new accelerator project that will operate in the years soon after 2010. We believe that the world high-energy physics community needs such a project. With the great promise of discovery in physics at the next energy scale, and with the opportunity for the uncovering of profound insights, we cannot allow our field to contract to a single experimental program at a single laboratory in the world. We believe that an e{sup +}e{sup {minus}} linear collider is an excellent choice for the next major project in high-energy physics. Applying experimental techniques very different from those used at hadron colliders, an e{sup +}e{sup {minus}} linear collider will allow us to build on the discoveries made at the Tevatron and the LHC, and to add a level of precision and clarity that will be necessary to understand the physics of the next energy scale. It is not necessary to anticipate specific results from the hadron collider programs to argue for constructing an e{sup +}e{sup {minus}} linear collider; in any scenario that is now discussed, physics will benefit from the new information that e{sup +}e{sup {minus}} experiments can provide.

Linear Collider Physics Resource Book for Snowmass 2001

Energy Technology Data Exchange (ETDEWEB)

Peskin, Michael E

2001-06-05

The American particle physics community can look forward to a well-conceived and vital program of experimentation for the next ten years, using both colliders and fixed target beams to study a wide variety of pressing questions. Beyond 2010, these programs will be reaching the end of their expected lives. The CERN LHC will provide an experimental program of the first importance. But beyond the LHC, the American community needs a coherent plan. The Snowmass 2001 Workshop and the deliberations of the HEPAP subpanel offer a rare opportunity to engage the full community in planning our future for the next decade or more. A major accelerator project requires a decade from the beginning of an engineering design to the receipt of the first data. So it is now time to decide whether to begin a new accelerator project that will operate in the years soon after 2010. We believe that the world high-energy physics community needs such a project. With the great promise of discovery in physics at the next energy scale, and with the opportunity for the uncovering of profound insights, we cannot allow our field to contract to a single experimental program at a single laboratory in the world. We believe that an e{sup +}e{sup -} linear collider is an excellent choice for the next major project in high-energy physics. Applying experimental techniques very different from those used at hadron colliders, an e{sup +}e{sup -} linear collider will allow us to build on the discoveries made at the Tevatron and the LHC, and to add a level of precision and clarity that will be necessary to understand the physics of the next energy scale. It is not necessary to anticipate specific results from the hadron collider programs to argue for constructing an e{sup +}e{sup -} linear collider; in any scenario that is now discussed, physics will benefit from the new information that e{sup +}e{sup -} experiments can provide.

Pulsed RF Sources for Linear Colliders

International Nuclear Information System (INIS)

Fernow, R.C.

1995-01-01

These proceedings represent papers presented at the workshop on pulsed RF sources for linear colliders. The workshop examined the performance of RF sources for possible future linear colliders. Important sources were presented on new type of klystrons, gyrotrons and gyroklystrons. A number of auxiliary topics were covered, including modulators, pulse compression, power extraction, windows, electron guns and gun codes. The workshop was sponsored by the International Committee for Future Accelerators(ICFA), the U.S. Department of Energy and the Center for Accelerator Physics at Brookhaven National Laboratory. There were forty one papers presented at the workshop and all forty one have been abstracted for the Energy Science and Technology database

Proton-antiproton colliding beam electron cooling

International Nuclear Information System (INIS)

Derbenev, Ya.S.; Skrinskij, A.N.

1981-01-01

A possibility of effective cooling of high-energy pp tilde beams (E=10 2 -10 3 GeV) in the colliding mode by accompanying radiationally cooled electron beam circulating in an adjacent storage ring is studied. The cooling rate restrictions by the pp tilde beam interaction effects while colliding and the beam self-heating effect due to multiple internal scattering are considered. Some techniques permitting to avoid self-heating of a cooling electron beam or suppress its harmful effect on a heavy particle beam cooling are proposed. According to the estimations the cooling time of 10 2 -10 3 s order can be attained [ru

Collide@CERN ProHelvetia Public Lecture

CERN Multimedia

CERN. Geneva; Heuer, Rolf; Mr. de Diesbach, Simon; Mr. Dubois, Marc; Ms. Perrenoud, Laura; Mr. Vust, Michel; Mrs. Bello, Monica

2015-01-01

You are very warmly invited to the opening presentation of Fragment.In’s residency at CERN. Fragment.In are the winners of Collide@CERN ProHelvetia, a collective formed by Laura Perrenoud, Simon de Diesbach, and Marc Dubois. They will present their artistic work along with their CERN scientific inspiration partner, who will present his/her work on Science. In their proposal, Fragment.In has a unique, original and creative approach to data visualization. We look forward to having them at CERN. Collide@CERN is the three month residency programme providing artists with time and space to reflect, research and renew their artistic practice.

The Large Hadron Collider in the LEP tunnel

International Nuclear Information System (INIS)

Brianti, G.; Huebner, K.

1987-01-01

The status of the studies for the CERN Large Hadron Collider (LHC) is described. This collider will provide proton-proton collisions with 16 TeV centre-of-mass energy and a luminosity exceeding 10 33 cm -2 s -1 per interaction point. It can be installed in the tunnel of the Large Electron-Positron Storage Ring (LEP) above the LEP elements. It will use superconducting magnets of a novel, compact design, having two horizontally separated channels for the two counter-rotating bunched proton beams, which can collide in a maximum of seven interaction points. Collisions between protons of the LHC and electrons of LEP are also possible with a centre-of-mass energy of up to 1.8 TeV and a luminosity of up to 2 x 10 32 cm -2 s -1 . (orig.)

A test accelerator for the next linear collider

International Nuclear Information System (INIS)

Ruth, R.D.; Adolphsen, C.; Bane, K.; Boyce, R.F.; Burke, D.L.; Callin, R.; Caryotakis, G.; Cassel, R.; Clark, S.L.; Deruyter, H.; Fant, K.; Fuller, R.; Heifets, S.; Hoag, H.; Humphrey, R.; Kheifets, S.; Koontz, R.; Lavine, T.; Loew, G.A.; Menegat, A.; Miller, R.H.; Paterson, J.M.; Pearson, C.; Phillips, R.; Rifkin, J.; Spencer, J.; Tantawi, S.; Thompson, K.A.; Vlieks, A.; Vylet, V.; Wang, J.W.; Wilson, P.B.; Yeremian, A.; Youngman, B.; Kroll, N.M.; Nantista, C.

1993-07-01

At SLAC, the authors are pursuing the design of a Next Linear Collider (NLC) which would begin with a center-of-mass energy of 0.5 TeV, and be upgradable to at least 1.0 TeV. To achieve this high energy, they have been working on the development of a high-gradient 11.4-GHz (X-band) linear accelerator for the main linac of the collider. In this paper, they present the design of a open-quotes Next Linear Collider Test Acceleratorclose quotes (NLCTA). The goal of the NLCTA is to incorporate the new technologies of X-band accelerator structures, RF pulse compression systems and klystrons into a short linac which will then be a test bed for beam dynamics issues related to high-gradient acceleration

Polarized electronic sources for future e+/e- linear colliders

International Nuclear Information System (INIS)

Tang, H.; Alley, R.K.; Clendenin, J.E.

1997-05-01

Polarized electron beams will play a crucial role in maximizing the physics potential for future e + /e - linear colliders. We will review the SLC polarized electron source (PES), present a design for a conventional PES for the Next Linear Collider (NLC), and discuss the physics issues of a polarized RF gun

Towards TeV-scale electron-positron collisions: the Compact Linear Collider (CLIC)

Science.gov (United States)

Doebert, Steffen; Sicking, Eva

2018-02-01

The Compact Linear Collider (CLIC), a future electron-positron collider at the energy frontier, has the potential to change our understanding of the universe. Proposed to follow the Large Hardron Collider (LHC) programme at CERN, it is conceived for precision measurements as well as for searches for new phenomena.

Production of high intensity electron bunches for the SLAC Linear Collider

International Nuclear Information System (INIS)

James, M.B.

1987-08-01

This thesis describes the design and performance of a high intensity electron injecfor for the SLAC Linear Collider. Motivation for the collider and the specifications for the injector are discussed. An analytic theory of the bunching and capture of electrons by rf fields is discussed in the limit of low space charge and small signal. The design and performance of SLAC's main injector are described to illustrate a successful application of this theory. The bunching and capture of electrons by rf fields are then discussed in the limit of high space charge and large signal, and a description of the design of the collider injector follows. In the limit of high space charge forces and large rf signals, the beam dynamics are considerably more complex and numerical simulations are required to predict particle motion. A computer code which models the longitudinal dynamics of electrons in the presence of space charge and rf fields is described. The results of the simulations, the resulting collider injector design and the various components which make up the collider injector are described. These include the gun, subharmonic bunchers, traveling-wave buncher and velocity-of-light accelerator section. Finally, the performance of the injector is described including the beam intensity, bunch length, transverse emittance and energy spectrum. While the final operating conditions differ somewaht from the design, the performance of the collider injector is in good agreement with the numerical simulations and meets all of the collider specifications. 28 refs

Progress towards the design of a next linear collider

International Nuclear Information System (INIS)

Ruth, R.D.

1990-06-01

The purpose of this paper is to review the ongoing research at SLAC toward the design of a next-generation linear collider (NLC). The energy of the collider is taken to be 0.5 TeV in the CM with a view towards upgrading to 1.0 TeV. The luminosity is in the range of 10 33 to 10 34 cm -2 sec -1 . The energy is achieved by acceleration with a gradient of about a factor of five higher than SLC, which yields a linear collider approximately twice as long as SLC. The detailed trade-off length and acceleration will be based on total cost. A very broad optimum occurs when the total linear costs equals the total cost of RF power. The luminosity of the linear collider is obtained basically in two ways. First, the cross-sectional area of the beam is decreased primarily by decreasing the vertical size. This creates a flat beam and is useful for controlling beamstrahlung. Secondly, several bunches (∼10) are accelerated on each RF fill in order to more efficiently extract energy from the RF structure. This effectively increases the repetition rate by an order of magnitude. In the next several sections, we trace the beam through the collider to review the research program at SLAC. 41 refs., 1 fig

Linear collider research and development at SLAC, LBL and LLNL

International Nuclear Information System (INIS)

Mattison, T.S.

1988-10-01

The study of electron-positron (e + e/sup /minus//) annihilation in storage ring colliders has been very fruitful. It is by now well understood that the optimized cost and size of e + e/sup /minus// storage rings scales as E(sub cm//sup 2/ due to the need to replace energy lost to synchrotron radiation in the ring bending magnets. Linear colliders, using the beams from linear accelerators, evade this scaling law. The study of e/sup +/e/sup /minus// collisions at TeV energy will require linear colliders. The luminosity requirements for a TeV linear collider are set by the physics. Advanced accelerator research and development at SLAC is focused toward a TeV Linear Collider (TLC) of 0.5--1 TeV in the center of mass, with a luminosity of 10/sup 33/--10/sup 34/. The goal is a design for two linacs of less than 3 km each, and requiring less than 100 MW of power each. With a 1 km final focus, the TLC could be fit on Stanford University land (although not entirely within the present SLAC site). The emphasis is on technologies feasible for a proposal to be framed in 1992. Linear collider development work is progressing on three fronts: delivering electrical energy to a beam, delivering a focused high quality beam, and system optimization. Sources of high peak microwave radio frequency (RF) power to drive the high gradient linacs are being developed in collaboration with Lawrence Berkeley Laboratory (LBL) and Lawrence Livermore National Laboratory (LLNL). Beam generation, beam dynamics and final focus work has been done at SLAC and in collaboration with KEK. Both the accelerator physics and the utilization of TeV linear colliders were topics at the 1988 Snowmass Summer Study. 14 refs., 4 figs., 1 tab

Working group report: Physics at the Large Hadron Collider

Indian Academy of Sciences (India)

cally viable physics issues at two hadron colliders currently under operation, the p¯p collider ... corrections to different SM processes are very important. ... Keeping all these in mind and the available skills and interests of the ... relation involving the masses of the Standard Model particles as well as the masses of any.

The possible hindrance of a 10 MW wind farm along the Noordermeerdijk in the Noordoostpolder, Netherlands, for birds

International Nuclear Information System (INIS)

Van den Bergh, L.M.J.; Spaans, A.L.

1993-01-01

The title farm comprises 14 two-bladed 750 kW wind turbines. Hindrance of wind turbines are collisions with the wind turbines and in the wake behind the blades and loss or disintegration of the natural habitat because of the presence of the wind turbines (aspect of disturbance). The title study is focused on counting the number of collision bird victims per year, and analyzing the disturbance effects on hibernating and foraging birds. It appeared that almost 150 to more than 1500 birds will collide with one of the 16 wind turbines. A few hundred tufted ducks, some tens of pochard and some tens of wild ducks per kilometer of the array will leave their natural habitat. Based on the results it is concluded that the site south of the kilometre marker 7.0 is preferred to the site directly south of kilometre marker 5.0. It is also concluded that the above-mentioned array is preferred to a wind turbine array of 16 wind turbines of 500 kW each. The results of the investigation on that array are published in a separate report for which a separate abstract has been prepared. 2 figs., 6 tabs., 2 appendices, 34 refs

Advances in beam physics and technology: Colliders of the future

Science.gov (United States)

Chattopadhyay, Swapan

1996-02-01

Beams may be viewed as directed and focussed flow of energy and information, carried by particles and electromagnetic radiation fields (i.e. photons). Often, they are brought into interaction with each other (e.g. in high energy colliders) or with other forms of matter (e.g. in fixed target physics, synchrotron radiation sciences, neutron scattering experiments, laser chemistry and physics, medical therapy, etc.). The whole art and science of beams revolve around the fundamental quest for, and ultimate implementation of, mechanisms of production, storage, control and observation of beams—always directed towards studies of the basic structures and processes of the natural world and various practical applications. Tremendous progress has been made in all aspects of beam physics and technology in the last decades—nonlinear dynamics, superconducting magnets and radio frequency cavities, beam instrumentation and control, novel concepts and collider paradigms, to name a few. We will illustrate this progress via a few examples and remark on the emergence of new collider scenarios where some of these progress might come to use—the Gamma-Gamma Collider, the Muon Collider, laser acceleration, etc. We will close with an outline of future opportunities and outlook.

High luminosity μ+ μ- collider: Report of a feasibility study

International Nuclear Information System (INIS)

Palmer, R.B.; Gallardo, J.C.; Tollestrup, A.; Sessler, A.

1996-12-01

Parameters are given of 4 TeV and 0.5 TeV (c-of-m) high luminosity μ + μ - colliders, and of a 0.5 TeV lower luminosity demonstration machine. We discuss the various systems in such muon colliders, starting from the proton accelerator needed to generate the muons and proceeding through muon cooling, acceleration and storage in a collider ring. Detector background, polarization, and nonstandard operating conditions are analyzed. Muon Colliders have unique technical and physics advantages and disadvantages when compared with both hadron and electron machines. They should thus be regarded as complementary. We briefly mention the luminosity requirements of hadrons and lepton machines and their high-energy-physics advantages and disadvantages in reference to their effective center of mass energy. Finally, we present an R ampersand D plan to determine whether such machines are practical

Symmetrization of the beam-beam interaction in an asymmetric collider

International Nuclear Information System (INIS)

Chin, Y.H.

1990-07-01

This paper studies the idea of symmetrizing both the lattice and the beams of an asymmetric collider, and discusses why this regime should be within the parametric reach of the design in order to credibly ensure its performance. Also examined is the effectiveness of a simple compensation method using the emittance as a free parameter and that it does not work in all cases. At present, when there are no existing asymmetric colliders, it seems prudent to design an asymmetric collider so as to be similar to a symmetric one (without relying on a particular theory of the asymmetric beam-beam interaction that has not passed tests of fidelity). Nevertheless, one must allow for the maximum possible flexibility and freedom in adjusting those parameters that affect luminosity. Such a parameter flexibility will be essential in tuning the collider to the highest luminosity

Proceedings of the first meeting on eγ/γγ colliders

International Nuclear Information System (INIS)

Watanabe, Isamu; Takahashi, Touru

1994-01-01

The first meeting on eγ/γγ colliders was held on September 28 and 29, 1993, at the National Laboratory for High Energy Physics. After general remarks were delivered, lectures were given on QED in intense laser field, photon linear collider, laser focusing, luminosity distribution in the eγ/γγ colliders, QCD correction for γγ→H, radiation correction for eγ/νW process, SUSY particle production at the eγ and γγ colliders, formation of e * in eγ collision, and general remarks on the theory. Discussion was carried out on 'Where are we going from here?' In this book, the gists of the lectures are collected. (K.I.)

High energy particle colliders: past 20 years, next 20 years and beyond

Energy Technology Data Exchange (ETDEWEB)

Shiltsev, Vladimir D.; /Fermilab

2012-04-01

Particle colliders for high energy physics have been in the forefront of scientific discoveries for more than half a century. The accelerator technology of the collider has progressed immensely, while the beam energy, luminosity, facility size and the cost have grown by several orders of magnitude. The method of colliding beams has not fully exhausted its potential but its pace of progress has greatly slowed down. In this paper we very briefly review the method and the history of colliders, discuss in detail the developments over the past two decades and the directions of the R and D toward near future colliders which are currently being explored. Finally, we make an attempt to look beyond the current horizon and outline the changes in the paradigm required for the next breakthroughs.

Beam dynamics problems for next generation linear colliders

International Nuclear Information System (INIS)

Yokoya, Kaoru

1990-01-01

The most critical issue for the feasibility of high-energy e + e - linear colliders is obviously the development of intense microwave power sources. Remaining problems, however, are not trivial and in fact some of them require several order-of-magnitude improvement from the existing SLC parameters. The present report summarizes the study status of the beam dynamics problems of high energy linear colliders with an exaggeration on the beam-beam phenomenon at the interaction region. There are four laboratories having linear collider plans, SLAC, CERN, Novosibirsk-Protovino, and KEK. The parameters of these projects scatter in some range but seem to converge slowly if one recalls the status five years ago. The beam energy will be below 500GeV. The basic requirements to the damping ring are the short damping time and small equilibrium emittance. All the proposed designs make use of tight focusing optics and strong wiggler magnets to meet these requirements and seem to have no major problems at least compared with other problems in the colliders. One of the major problems in the linac is the transverse beam blow-up due to the wake field created by the head of the bunch and, in the case of multiple bunches per pulse, by the preceeding bunches. (N.K.)

The 20th Hadron Collider Physics Symposium in Evian