Silicate Based Glass Formulations for Immobilization of U.S. Defense Wastes Using Cold Crucible Induction Melters

Energy Technology Data Exchange (ETDEWEB)

Smith, Gary L.; Kim, Dong-Sang; Schweiger, Michael J.; Marra, James C.; Lang, Jesse B.; Crum, Jarrod V.; Crawford, Charles L.; Vienna, John D.

2014-05-22

The cold crucible induction melter (CCIM) is an alternative technology to the currently deployed liquid-fed, ceramic-lined, Joule-heated melter for immobilizing of U.S. tank waste generated from defense related reprocessing. In order to accurately evaluate the potential benefits of deploying a CCIM, glasses must be developed specifically for that melting technology. Related glass formulation efforts have been conducted since the 1990s including a recent study that is first documented in this report. The purpose of this report is to summarize the silicate base glass formulation efforts for CCIM testing of U.S. tank wastes. Summaries of phosphate based glass formulation and phosphate and silicate based CCIM demonstration tests are reported separately (Day and Ray 2013 and Marra 2013, respectively). Combined these three reports summarize the current state of knowledge related to waste form development and process testing of CCIM technology for U.S. tank wastes.

Study on superheat of TiAl melt during cold crucible levitation melting. TiAl no cold crucible levitation yokai ni okeru yoto kanetsudo no kenkyu

Energy Technology Data Exchange (ETDEWEB)

Miwa, K.; Kobayashi, K.; Ninomiya, M. (Government Industrial Research Institute, Nagoya, Nagoya (Japan))

1992-06-20

Investigations were given on effects of test sample weights and sample positions in cold crucibles on superheat of melts when the intermetallic compound TiAl is melted using cold crucible levitation melting process, one of noncontaminated melting processes. The cold crucibles used in the experiment are a water-cooled copper crucible with an inner diameter of 42 mm and a length of 140 mm, into which a column-like ingot sample with an outer diameter of 32 mm (Al containing Ti at 33.5% by mass) was put and melted using the levitation melting. Comparisons and discussions were given on the relationship between sample weights and melt temperatures, the relationship between positions of the inserted samples and melt temperatures, and the state of contamination at melting of casts obtained from the melts resulted from the levitation melting and high-frequency melting poured into respective ceramic dies. Elevating the superheat temperature of the melts requires optimizing the sample weights and positions. Melt temperatures were measured using a radiation thermometer and a thermocouple, and the respective measured values were compared. 7 refs., 4 figs., 1 tab.

FEASIBILITY EVALUATION AND RETROFIT PLAN FOR COLD CRUCIBLE INDUCTION MELTER DEPLOYMENT IN THE DEFENSE WASTE PROCESSING FACILITY AT SAVANNAH RIVER SITE 8118

International Nuclear Information System (INIS)

Barnes, A; Dan Iverson, D; Brannen Adkins, B

2008-01-01

Cold crucible induction melters (CCIM) have been proposed as an alternative technology for waste glass melting at the Defense Waste Processing Facility (DWPF) at Savannah River Site (SRS) as well as for other waste vitrification facilities. Proponents of this technology cite high temperature operation, high tolerance for noble metals and aluminum, high waste loading, high throughput capacity, and low equipment cost as the advantages over existing Joule Heated Melter (JHM) technology. The CCIM uses induction heating to maintain molten glass at high temperature. A water-cooled helical induction coil is connected to an AC current supply, typically operating at frequencies from 100 KHz to 5 MHz. The oscillating magnetic field generated by the oscillating current flow through the coil induces eddy currents in conductive materials within the coil. Those oscillating eddy currents, in turn, generate heat in the material. In the CCIM, the induction coil surrounds a 'Cold Crucible' which is formed by metal tubes, typically copper or stainless steel. The tubes are constructed such that the magnetic field does not couple with the crucible. Therefore, the field generated by the induction coil couples primarily with the conductive medium (hot glass) within. The crucible tubes are water cooled to maintain their temperature between 100 C to 200 C so that a protective layer of molten glass and/or batch material, referred to as a 'skull', forms between them and the hot, corrosive melt. Because the protective skull is the only material directly in contact with the molten glass, the CCIM doesn't have the temperature limitations of traditional refractory lined JHM. It can be operated at melt temperatures in excess of 2000 C, allowing processing of high waste loading batches and difficult-to-melt compounds. The CCIM is poured through a bottom drain, typically through a water-cooled slide valve that starts and stops the pour stream. To promote uniform temperature distribution and

Summary Of Cold Crucible Vitrification Tests Results With Savannah River Site High Level Waste Surrogates

Energy Technology Data Exchange (ETDEWEB)

Stefanovsky, Sergey; Marra, James; Lebedev, Vladimir

2014-01-13

The cold crucible inductive melting (CCIM) technology successfully applied for vitrification of low- and intermediate-level waste (LILW) at SIA Radon, Russia, was tested to be implemented for vitrification of high-level waste (HLW) stored at Savannah River Site, USA. Mixtures of Sludge Batch 2 (SB2) and 4 (SB4) waste surrogates and borosilicate frits as slurries were vitrified in bench- (236 mm inner diameter) and full-scale (418 mm inner diameter) cold crucibles. Various process conditions were tested and major process variables were determined. Melts were poured into 10L canisters and cooled to room temperature in air or in heat-insulated boxes by a regime similar to Canister Centerline Cooling (CCC) used at DWPF. The products with waste loading from ~40 to ~65 wt.% were investigated in details. The products contained 40 to 55 wt.% waste oxides were predominantly amorphous; at higher waste loadings (WL) spinel structure phases and nepheline were present. Normalized release values for Li, B, Na, and Si determined by PCT procedure remain lower than those from EA glass at waste loadings of up to 60 wt.%.

Chemically durable iron phosphate glasses for vitrifying sodium bearing waste (SBW) using conventional and cold crucible induction melting (CCIM) techniques

Energy Technology Data Exchange (ETDEWEB)

Kim, C.W. E-mail: cheol@umr.edu; Ray, C.S.; Zhu, D.; Day, D.E.; Gombert, D.; Aloy, A.; Mogus-Milankovic, A.; Karabulut, M

2003-11-01

A simulated sodium bearing waste (SBW) was successfully vitrified in iron phosphate glasses (IPG) at a maximum waste loading of 40 wt% using conventional and cold crucible induction melting (CCIM) techniques. No sulfate segregation or crystalline phases were detectable in the IPG when examined by SEM and XRD. The IPG wasteforms containing 40 wt% SBW satisfy current DOE requirements for aqueous chemical durability as evaluated from their bulk dissolution rate (D{sub R}), product consistency test, and vapor hydration test. The fluid IPG wasteforms can be melted at a relatively low temperature (1000 deg. C) and for short times (<6 h). These properties combined with a significantly higher waste loading, and the feasibility of CCIM melting offer considerable savings in time, energy, and cost for vitrifying the SBW stored at the Idaho National Engineering and Environmental Laboratory in iron phosphate glasses.

Crucible and coil monitoring during melting operation in induction crucible furnaces; Tiegel- und Spulenueberwachung beim Schmelzbetrieb von Induktionstiegeloefen

Energy Technology Data Exchange (ETDEWEB)

Doetsch, Erwin; Forsthoevel, Christoph; Rische, Marco [ABP Induction Systems GmbH, Dortmund (Germany)

2013-03-15

The immediate proximity of the metal melt, with a temperature of up to above, 1600 C, to the induction coil in inductive melting necessitates highly reliable monitoring systems, in order to prevent dangerous contact between the melt and the cooling-water-conducting copper section. Ground-fault monitoring, in which the electrical resistance between the melt and the coil is continuously measured, is a standard solution for this function. Everyday use of this long-established system has been made more dependable by automating a number of functions, and the system has also been adapted to modern plant technology, including synchronous tandem operation of two crucible furnaces from a common converter power supply, for example. Measurement of frequency and effective power, as a function of wall thickness, is a supplementary monitoring strategy. Processing of the measured data in the melt processor, in combination with visual assessment, permits appraisal of the integral crucible state and reliable estimation of the remaining service-life of the current crucible. (orig.)

Cold-Crucible Design Parameters for Next Generation HLW Melters

International Nuclear Information System (INIS)

Gombert, D.; Richardson, J.; Aloy, A.; Day, D.

2002-01-01

The cold-crucible induction melter (CCIM) design eliminates many materials and operating constraints inherent in joule-heated melter (JHM) technology, which is the standard for vitrification of high-activity wastes worldwide. The cold-crucible design is smaller, less expensive, and generates much less waste for ultimate disposal. It should also allow a much more flexible operating envelope, which will be crucial if the heterogeneous wastes at the DOE reprocessing sites are to be vitrified. A joule-heated melter operates by passing current between water-cooled electrodes through a molten pool in a refractory-lined chamber. This design is inherently limited by susceptibility of materials to corrosion and melting. In addition, redox conditions and free metal content have exacerbated materials problems or lead to electrical short-circuiting causing failures in DOE melters. In contrast, the CCIM design is based on inductive coupling of a water-cooled high-frequency electrical coil with the glass, causing eddycurrents that produce heat and mixing. A critical difference is that inductance coupling transfers energy through a nonconductive solid layer of slag coating the metal container inside the coil, whereas the jouleheated design relies on passing current through conductive molten glass in direct contact with the metal electrodes and ceramic refractories. The frozen slag in the CCIM design protects the containment and eliminates the need for refractory, while the corrosive molten glass can be the limiting factor in the JH melter design. The CCIM design also eliminates the need for electrodes that typically limit operating temperature to below 1200 degrees C. While significant marketing claims have been made by French and Russian technology suppliers and developers, little data is available for engineering and economic evaluation of the technology, and no facilities are available in the US to support testing. A currently funded project at the Idaho National Engineering

Vitrification of HLLW Surrogate Solutions Containing Sulfate in a Direct-Induction Cold Crucible Melter

International Nuclear Information System (INIS)

Tronche, E.; Lacombe, J.; Ledoux, A.; Boen, R.; Ladirat, C.H.

2009-01-01

Efforts were made in the People's Republic of China to solidify legacy high level liquid waste (HLLW) by the Liquid-Fed Ceramic Melter process (LFCM) in the 1990's. This process was to be a continuous process with high throughput as in the French Marcoule Vitrification Plant (AVM) or the LFCM. In this context, the CEA (Commissariat a l'Energie Atomique is a French government-funded technological research organization) suggests the Cold Crucible Induction Melter (CCIM) technology that has been developed by the CEA since the 1980's to improve the performance of the vitrification process. In this context a series of vitrification tests has been carried out in a CCIM. CEA and AREVA have designed an integrated platform based on the CCIM technology on a sufficient scale to be used for demonstration programs of the one-step process. In 2003 a test was carried out at Marcoule in southern France on simulated HLLW with high sulfur content. In order to ensure the tests performed at Marcoule were consistent with the Chinese waste-forms, the glass frit was supplied by a Chinese Industry. The CCIM facility is described in detail, including process instrumentation. The test run is also described, including how the solution was directly fed on the surface of the molten glass. A maximum capacity was determined according to the applied process parameters including the high operating temperature. The electrical power supply characteristics are detailed and a glass mass balance is also presented covering more than seven hundred kilograms of glass produced in a sixty-hour test run. (authors)

Experimental results for TiO2 melting and release using cold crucible melting

International Nuclear Information System (INIS)

Hong, S. W.; Min, B. T.; Park, I. G.; Kim, H. D.

2000-01-01

To simulate the severe accident phenomena using the real reactor material which melting point is about 2,800K, the melting and release method for materials with high melting point should be developed. This paper discusses the test results for TiO 2 materials using the cold crucible melting method to study the melting and release method of actual corium. To melt and release of few kg of TiO2, the experimental facility is manufactured through proper selection of design parameters such as frequency and capacity of R.F generator, crucible size and capacity of coolant. The melting and release of TiO 2 has been successfully performed in the cold crucible of 15cm in inner diameter and 30cm in height with 30kW RF power generator of 370 KHz. In the melt delivery experiment, about 2.6kg of molten TiO2, 60% of initial charged mass, is released. Rest of it is remained in the watercage in form of the rubble crust formed at the top of crucible and melt crust formed at the interface between the water-cage and melt. Especially, in the melt release test, the location of the working coil is important to make the thin crust at the bottom of the crucible

VIBROCASTING CRUCIBLES OF DIFFERENT COMPOSITION FOR FRYING INDUCTION MELTING ALLOYS

OpenAIRE

V. V. Primachenko; V. V. Martynenko; I. G. Szulik; S. V. Chaplyanko; L. V. Gritsyuk; L. P. Tkachenko

2012-01-01

It is shown that PSC «UKRNIIO them. A.S.Berezhnogo  has developed technologies for a wide range of induction melting temperature alloys and started commercial production of crucibles of different composition.

VIBROCASTING CRUCIBLES OF DIFFERENT COMPOSITION FOR FRYING INDUCTION MELTING ALLOYS

Directory of Open Access Journals (Sweden)

V. V. Primachenko

2012-01-01

Full Text Available It is shown that PSC «UKRNIIO them. A.S.Berezhnogo  has developed technologies for a wide range of induction melting temperature alloys and started commercial production of crucibles of different composition.

Plasma arc and cold crucible furnace vitrification for medium level waste: a review

International Nuclear Information System (INIS)

Poitou, S.; Fiquet, O.; Bourdeloie, C.; Gramondi, P.; Rebollo, F.; Girold, C.; Charvillat, J.P.; Boen, R.; Jouan, A.; Ladirat, C.; Nabot, J.P.; Ochem, D.; Baronnet, J.M.

2001-01-01

Initially developed for high-level waste reprocessing, several vitrification processes have been under study since the 80's at the French Atomic Energy Commission (CEA) for other waste categories. According to the French law concerning waste management research passed on December 30, 1991, vitrification may be applied to mixed medium-level waste. A review of processes developed at CEA is presented: cold crucible furnace heated by induced current, refractory furnace heated by nitrogen transferred arc plasma torch, and coupling of cold crucible furnace with oxygen transferred plasma arc twin torch. Furthermore, gas post-combustion has been studied with an oxygen non-transferred plasma torch. (authors)

Investigation of U3O8 immobilization in the GP-91 borosilicate glass by induction melter with a cold crucible (CCIM)

International Nuclear Information System (INIS)

Matyunin, Y.I.; Demin, A.V.; Smelova, T.V.; Yudintsev, S.V.; Lapina, M.I.

1997-01-01

One of the most promising and intensively developed methods for the solidification of high-level wastes is their vitrification with the use of a cold crucible induction melter (CCIM), which offers a number of advantages over ceramic melter. This work is concerned with comparison studies on the behavior of uranium in vitreous borosilicate materials synthesized by the traditional technique (melting in muffle furnaces) and CCIM method. The incorporation of uranium oxide U 3 O 8 into the GP-91 borosilicate glass with the use of CCIM technology is investigated. The limiting solubility of uranium in the GP-91 borosilicate glass is evaluated. The phase composition of precipitated dispersed particles based on uranium is determined. Some physicochemical properties of synthesized materials are explored. Investigations into the behavior of uranium in borosilicate glass prepared in the CCIM show a feasibility to synthesize the X-ray amorphous homogeneous borosilicate glasses incorporating as much as 25 - 28 wt% uranium, which is 4 - 5 times larger than that in glasses obtained by the traditional method. (author)

Induction melter apparatus

Science.gov (United States)

Roach, Jay A [Idaho Falls, ID; Richardson, John G [Idaho Falls, ID; Raivo, Brian D [Idaho Falls, ID; Soelberg, Nicholas R [Idaho Falls, ID

2008-06-17

Apparatus and methods of operation are provided for a cold-crucible-induction melter for vitrifying waste wherein a single induction power supply may be used to effect a selected thermal distribution by independently energizing at least two inductors. Also, a bottom drain assembly may be heated by an inductor and may include an electrically resistive heater. The bottom drain assembly may be cooled to solidify molten material passing therethrough to prevent discharge of molten material therefrom. Configurations are provided wherein the induction flux skin depth substantially corresponds with the central longitudinal axis of the crucible. Further, the drain tube may be positioned within the induction flux skin depth in relation to material within the crucible or may be substantially aligned with a direction of flow of molten material within the crucible. An improved head design including four shells forming thermal radiation shields and at least two gas-cooled plenums is also disclosed.

RNi2B2C (R = Ho, Dy, Tb and Pr) single crystals grown by the cold copper crucible method

Science.gov (United States)

Durán, A.; Munoz, E.; Bernès, S.; Escudero, R.

2000-08-01

Single crystals of RNi2B2C (R = Ho, Dy, Tb, Pr) have been grown on cold copper crucibles in a high-frequency induction furnace. As a result, shiny metallic and brittle platelike single crystals were obtained. They were examined by x-ray and scanning electron microscopy with WDX/EDX for local composition analysis and show a very good crystallographic structure and compositions. Resistivity and dc magnetic measurements were performed to study superconducting and magnetic properties. Besides known electronic properties of the RNi2B2C family, we report for the first time results for PrNi2B2C single crystals successfully obtained by this technique.

Cold-crucible melting of hulls and structural materials

International Nuclear Information System (INIS)

Jouan, A.; Jacquet-Francillon, N.; Puyou, M.; Piccinato, R.

1990-01-01

The method currently implemented at the La Hague UP3 reprocessing plant for conditioning of PWR zircaloy hulls is cement embedding. Another promising method, mainly for reducing the waste volume and the available exchange surface area, is melting. A cold-crucible melting process has therefore been developed by the CEA at Marcoule (France) over the last decade. Development work first concentrated on cladding hulls from fast breeder reactors, then from pressurized water reactors. The process can be used for both types of cladding wastes. Subassembly head and foot end-caps are sheared off and should be suitable for surface storage after α decontamination by successive rinsing. If necessary because of their α activity, they could be melted in a larger furnace

Letter report: Cold crucible melter assessment

International Nuclear Information System (INIS)

Elliott, M.L.

1996-03-01

One of the activities of the PNL Vitrification Technology Development (PVTD) Project is to assist the Tank Waste Remediation Systems (TWRS) Program in determining which melter systems should be performance tested for potential implementation in the high-level waste (HLW) vitrification plant. The Richland Operations Office (RL) has recommended that the Cold Crucible Melter (CCM) be evaluated as a candidate ''next generation'' melter. As a result, the CCM System Evaluation cost account was established under the PVTD Project so that the CCM could be initially assessed on a high-priority basis. This letter report summarizes a brief initial review and assessment of the CCM. Using the recommendations made in this document, Westinghouse Hanford Company (WHC) and RL will make a decision regarding the urgency of performance testing the CCM. If the decision is favorable, a subcontract will be negotiated for performance testing of a CCM using Hanford HLW simulants in a pilot-scale facility. Because of the aggressive nature of the schedule, the CCM evaluation was not rigorous. The evaluation consisted of a literature review and interviews with proponents of the technology during a recent trip to France. This letter report summarizes the evaluation and makes recommendations regarding further work in this area

High quality vacuum induction melting of small quantities of NiTi shape memory alloys in graphite crucibles

International Nuclear Information System (INIS)

Frenzel, J.; Zhang, Z.; Neuking, K.; Eggeler, G.

2004-01-01

Binary NiTi based shape memory alloys can be produced starting from the pure elements (Ni-pellets, Ti-rods) by using vacuum induction melting (VIM). VIM ingot metallurgy is known to produce materials with a good chemical homogeneity; it, moreover, is cheaper than vacuum arc melting (VAM) when small quantities of laboratory materials are needed. In a VIM procedure, graphite crucibles are attractive because they have appropriate electrical properties. For NiTi melting, graphite crucibles are interesting because they are reasonably priced and they show a good resistance against thermal cracking. On the other hand, it is well known that melting of Ti alloys in graphite crucibles is associated with a vigorous interface reaction. And the carbon concentration of NiTi alloys needs to be kept below a certain minimum in order to assure that the functional properties of the alloys meet the required targets. Therefore, it is important to minimize the carbon pick up of the melt. The present work presents experimental results and discusses thermodynamic and kinetic aspects of the reaction of NiTi melts with graphite crucibles; a method is suggested to keep the carbon dissolution into the melt at a minimum

The mechanism of hot crack formation in Ti-6A1-4V during cold crucible continuous casting

Directory of Open Access Journals (Sweden)

Hongsheng DING

2004-08-01

Full Text Available Hot crack is one of common defects in castings, which often results in failure of castings. This work studies the formation of hot cracks during cold crucible continous casting by means of experiments and thoretical analysis. The results show that the hot crack occurs on the surface and in the circumference of ingots, where the solidified shell and solidification front meet each other. The tendency of hot cracking decreases with the increase of withdrawal velocities in some extent. The hot crack is caused mainly by friction force between the shell and the crucible inner wall, and it takes place when the stress resulting from friction exceeds the tensile strength of the shell. The factors affecting the hot cracks are analyzed and verified. In order to decrease the tendency of hot cracks, technical parameters should be optimized.

Cold crucible technique for interaction test of molten corium with structure

International Nuclear Information System (INIS)

Ha, Kwang Soon; An, Sang Mo; Min, Beong Tae; Kim, Hwan Yeol

2012-01-01

During a severe accident, the molten corium might interact with several structures in a nuclear power plant such as core peripheral structures, lower plenum, lower head vessel, and external structures of a reactor vessel. The interaction of the molten corium with the structure depends on the molten corium composition, temperature, structural materials, and environmental conditions such as pressure and humidity. For example, the interaction of a metallic molten corium containing metal uranium (U) and zirconium (Zr) with the oxidized steel structure (Fe 2O3 ) is affected by not only thermal ablation but oxidation reduction reaction because the oxidation quotients of the U and Zr are higher than that of Fe. KAERI set up an experimental facility and technique using a cold crucible melting method to verify the interaction mechanism between the metallic molten corium and structural materials. This technique includes the generation of the metallic melt, melt delivery, measurement of the interaction process, and post analyses after the test

Generalized Test Plan for the Vitrification of Simulated High-Level -Waste Calcine in the Idaho National Laboratory's Bench -Scale Cold Crucible Induction Melter

International Nuclear Information System (INIS)

Maio, Vince

2011-01-01

This Preliminary Idaho National Laboratory (INL) Test Plan outlines the chronological steps required to initially evaluate the validity of vitrifying INL surrogate (cold) High-Level-Waste (HLW) solid particulate calcine in INL's Cold Crucible Induction Melter (CCIM). Its documentation and publication satisfies interim milestone WP-413-INL-01 of the DOE-EM (via the Office of River Protection) sponsored work package, WP 4.1.3, entitled 'Improved Vitrification' The primary goal of the proposed CCIM testing is to initiate efforts to identify an efficient and effective back-up and risk adverse technology for treating the actual HLW calcine stored at the INL. The calcine's treatment must be completed by 2035 as dictated by a State of Idaho Consent Order. A final report on this surrogate/calcine test in the CCIM will be issued in May 2012-pending next fiscal year funding In particular the plan provides; (1) distinct test objectives, (2) a description of the purpose and scope of planned university contracted pre-screening tests required to optimize the CCIM glass/surrogate calcine formulation, (3) a listing of necessary CCIM equipment modifications and corresponding work control document changes necessary to feed a solid particulate to the CCIM, (4) a description of the class of calcine that will be represented by the surrogate, and (5) a tentative tabulation of the anticipated CCIM testing conditions, testing parameters, sampling requirements and analytical tests. Key FY -11 milestones associated with this CCIM testing effort are also provided. The CCIM test run is scheduled to be conducted in February of 2012 and will involve testing with a surrogate HLW calcine representative of only 13% of the 4,000 m3 of 'hot' calcine residing in 6 INL Bin Sets. The remaining classes of calcine will have to be eventually tested in the CCIM if an operational scale CCIM is to be a feasible option for the actual INL HLW calcine. This remaining calcine's make-up is HLW containing

Microstructure and mechanical properties of cast Ti-47Al-2Cr-2Nb alloy melted in various crucibles

Directory of Open Access Journals (Sweden)

Wang Ligang

2012-02-01

Full Text Available The main factors limiting the mass production of TiAl-based components are the high reactivity of TiAl-based alloys with the crucible or mould at high temperature. In this work, various crucibles (e.g. CaO, Y2O3 ceramic crucibles and water-cooled copper crucible were used to fabricate the Ti-47Al-2Cr-2Nb alloy in a vacuum induction furnace. The effects of crucible materials and melting parameters on the microstructure and mechanical properties of the alloy were analyzed by means of microstructure observation, chemical analysis, tensile test and fracture surface observation. The possibilities of melting TiAl alloys in crucibles made of CaO and Y2O3 refractory materials were also discussed.

Direct induction skull melting for glass and vitreous materials (Fly ash- oxides - salts)

Energy Technology Data Exchange (ETDEWEB)

Uring, J.C. [Celes, 68 - Lautenbach (France); Van den Broek, J. [Promethee, 92 - Paris-la-Defense (France)

1997-12-31

Direct coil cold crucibles appear as the most economic and reliable furnaces for vitrifying solid wastes. The efficiency is excellent, as the electromagnetic energy is only transferred into the melt and the power dissipation in the walls of the crucible is negligible. The walls of the crucible are cooled, so a skull of cold material protects the metal or the lining of the crucible. Application to municipal solid waste fly ashes is discussed

Two-Crucible Czochralski Process

Science.gov (United States)

Fiegl, G.; Torbet, W.

1985-01-01

Scheme for continuous melt replenishment increases capacity of Czochralski crystal-growing furnace. Replenishing and drawing crucibles of improved Czochralski apparatus connected by heated quartz siphon. When doped silicon added to replenishing crucible, liquid silicon flows into drawing crucible, equalizing two melt levels. Addition of new material automatically controlled in response to optically sensed melt level. Results of this semicontinuous operation higher production speed, lower cost, and good control of crystal quality.

Aluminum titanate crucible for molten uranium

International Nuclear Information System (INIS)

Asbury, J.J.

1975-01-01

An improved crucible for molten uranium is described. The crucible or crucible liner is formed of aluminum titanate which essentially eliminates contamination of uranium and uranium alloys during molten states thereof. (U.S.)

Glass manufacturing through induction

International Nuclear Information System (INIS)

Boen, R.; Paya, B.; Roscini, M.; Fautrelle, Y.; Tuaz, F.; Delage, D.

1991-01-01

Oxides and glasses are electrical and thermal insulators, but show the characteristic of being weakly conductors of electricity when they are melt. It is then possible to heat them through HF induction. This interesting property allows the development of a melting process in cold crucible induction furnace. The process is being studied and developed by a consortium made up of CFEI, CEA Marcoule, ELECTRICITE DE FRANCE and MADYLAM laboratory. The studies include 2 parts: a) One experimental part to develop the technology and research for satisfying configurations, through a small size platform (10 to 30 kg/h). The long run continuous pouring melting tests made on different kinds of glass allow to go-on with industrial range units. b) One theoretical part to understand the magneto-thermo-hydraulic phenomenon hardly in relation with the heavy dependence of the physical characteristics (electrical and heat conductivities, viscosity) according to temperature. 6 refs., 4 figs [fr

Electrical resistivity of ceramic-metal composite materials in the percolation region: application in crucibles for induction furnaces; Resistividade eletrica de materiais compositos do tipo ceramica-metal na regiao de percolacao: aplicacao em cadinhos para fornos de inducao

Energy Technology Data Exchange (ETDEWEB)

Sene, Frank Ferrer

1997-07-01

Ceramic composite materials were produced by mixing powders of Partially Stabilized (PSZ) with titanium, niobium or nickel, and cristobalite with titanium. Pellets were produced by uniaxially pressing the material followed by cold isostatic pressing and finally sintering at 1600 deg C for 1,5 hours in argon. The metal content was varied in the range of 0-40 volume percent (v/o). Electrical resistivity measurements were performed in the temperature range of 25 - 700 deg C. Samples containing metallic inclusions above 25 v/o show the predominance of electronic type conducting. For samples with metallic inclusion below 25 v/o, a typically ionic conduction behavior has been observed. PSZ-Ti and PSZ-Ni samples containing 25 v/o of metallic inclusions show an insulator - conductor transition in a given temperature range. Cristobalite samples containing 30 v/o of titanium show a conductor - insulator transition also in a specific temperature range. Tests performed in an induction furnace showed that samples containing metallic inclusions above 25 v/o had self-heated when exposed to electro magnetic fields in the range of radio frequency (r.f.) Crucibles of PSZ-Ti were made by slip casting followed by sintering at 1600 deg C for 1.5 hours in argon. These crucibles were exposed to electromagnetic fields in the r.f. range and the maximum temperature reached was 1350 deg C. Microstructure characterization was performed on those materials by X-ray diffraction, EDS, optical and scanning electron microscopy. (author)

Melting method for radioactive solid wastes and device therefor

Energy Technology Data Exchange (ETDEWEB)

Komatsu, Masahiko; Abe, Takashi; Nakayama, Junpei; Kusamichi, Tatsuhiko; Sakamoto, Koichi

1998-11-17

Upon melting radioactive solid wastes mixed with radioactive metal wastes and non metal materials such as concrete by cold crucible high frequency induction heating, induction coils are wound around the outer circumference of a copper crucible having a water cooling structure to which radioactive solid wastes are charged. A heating sleeve formed by a material which generates heat by an induction heating function of graphite is disposed to the inside of the crucible at a height not in contact with molten metals in the crucible vertically movably. Radioactive solid wastes are melted collectively by the induction heat of the induction coils and thermal radiation and heat conduction of the heating sleeve heated by the induction heat. With such procedures, non metal materials such as concrete and radioactive metal wastes in a mixed state can be melt collectively continuously highly economically. (T.M.)

Numerical analysis of the induction melting process of oxide fuel material

International Nuclear Information System (INIS)

Kondala Rao, R.; Mangarjuna Rao, P.; Nashine, B.K.; Selvaraj, P.

2015-01-01

For the experimental simulation of Molten Fuel-Coolant Interaction (MFCI) phenomenon under hypothetical core meltdown accident scenario in a nuclear reactor, it is required to generate the molten pool of core materials. For this purpose, a laboratory scale Cold wall Crucible induction melting system has been developed. To optimize the system for efficient and reliable melting process, it is required to have comprehensive knowledge on the heat and mass transfer processes along with electromagnetic process that occur during the melting of core materials. Hence, a 2D axi-symmetric numerical model has been developed using a multiphysics software to simulate the induction melting process. The phase change phenomenon is taken into account by using enthalpy formulation. The experimental data available in literature for magnetic field and flow field are used for model validation. The model predicted temperatures are also in good agreement with experimentally measured values. The validated model has been used to study the induction melting behavior of UO_2 fuel material. (author)

Refractory material crucibles evaluation for U evaporation

International Nuclear Information System (INIS)

Damiao, A.J.; Vasconcelos, G.; Silveira, C.A.B.; Rodrigues, N.A.S.

1996-01-01

In studies that involve small amounts of U vapor generation, such as spectroscopy or thin films, most of the E-gun power is delivered to the cooling system. Normally crucibles are used as container and thermal insulator. Since liquid U is extremely reactive at evaporation temperatures, the crucibles are seriously attacked, decreasing the insulation efficiency and adding contaminants to the U vapor. There is no complete solution for the problem, however, with a careful choice of materials, one can design crucibles with extended lifetime and reduced contamination. This work reports some preliminary results we have obtained in the assessing of crucible materials and design, such as, graphite, Si C, vitreous carbon and Al 2 O 3 . (author)

Iron Phosphate Glass for Vitrifying Hanford AZ102 LAW in Joule Heated and Cold Crucible Induction Melters - 12240

Energy Technology Data Exchange (ETDEWEB)

Day, Delbert E.; Brow, Richard K.; Ray, Chandra S.; Reis, Signo T. [Missouri University of Science and Technology, 1870 Miner Circle, Rolla, MO 65409 (United States); Kim, Cheol-Woon [MO-SCI Corporation, 4040 HyPoint North, Rolla, MO 65401 (United States); Vienna, John D.; Sevigny, Gary [Pacific North West National Laboratory, Battelle Blvd., Richland, WA 99352 (United States); Peeler, David; Johnson, Fabienne C.; Hansen, Eric K. [Savannah River National Laboratory, Savannah River Site, 999-W, Aiken, SC 29803 (United States); Soelberg, Nick [Idaho National Laboratory, 2525 Fremont Avenue, Idaho Falls, ID 83415 (United States); Pegg, Ian L.; Gan, Hao [Catholic University of America, 620 Michigan Avenue, N.E., Washington, DC 20064 (United States)

2012-07-01

An iron phosphate composition for vitrifying a high sulfate (∼17 wt%) and high alkali (∼80 wt%) Hanford low activity waste (LAW), known as AZ-102 LAW, has been developed for processing in a Joule Heated Melter (JHM) or a Cold Crucible Induction Melter (CCIM). This composition produced a glass waste form, designated as MS26AZ102F-2, with a waste loading of 26 wt% of the AZ-102 which corresponded to a total alkali and sulfate (represented as SO{sub 3}) content of 21 and 4.4 wt%, respectively. A slurry (7 M Na{sup +}) of MS26AZ102F-2 simulant was melted continuously at temperatures between 1030 and 1090 deg. C for 10 days in a small JHM at PNNL and for 70 hours in a CCIM at INL. The as-cast glasses produced in both melters and in trial laboratory experiments along with their canister centerline cooled (CCC) counterparts met the requirements for the Product Consistency Test (PCT) and the Vapor Hydration Test (VHT) responses in the Hanford Tank Waste Treatment and Immobilization Plant (WTP) Contract. These glass waste forms retained up to 77 % of the SO{sub 3} (3.3 wt%), 100% of the Cesium, and 33 to 44% of the rhenium (used as a surrogate for Tc) all of which either exceeded or were comparable to the retention limit for these species in borosilicate glass nuclear waste form. Analyses of commercial K-3 refractory lining and the Inconel 693 metal electrodes used in JHM indicated only minimum corrosion of these components by the iron phosphate glass. This is the first time that an iron phosphate composition was melted continuously in a slurry fed JHM and in the US, thereby, demonstrating that iron phosphate glasses can be used as alternative hosts for vitrifying nuclear waste. The following conclusions are drawn from the results of the present work. (1) An iron phosphate composition, designated as MS26AZ102F-2, containing 26 wt% of the simulated high sulfate (17 wt%), high alkali (80 wt%) Hanford AZ-102 LAW meets all the criteria for processing in a JHM and CCIM. This

Refractory material crucibles evaluation for U evaporation

Energy Technology Data Exchange (ETDEWEB)

Damiao, A.J.; Vasconcelos, G.; Silveira, C.A.B.; Rodrigues, N.A.S. [Centro Tecnico Aeroespacial (CTA-IEAv), Sao Jose dos Campos, SP (Brazil). Inst. de Estudos Avancados

1996-12-31

In studies that involve small amounts of U vapor generation, such as spectroscopy or thin films, most of the E-gun power is delivered to the cooling system. Normally crucibles are used as container and thermal insulator. Since liquid U is extremely reactive at evaporation temperatures, the crucibles are seriously attacked, decreasing the insulation efficiency and adding contaminants to the U vapor. There is no complete solution for the problem, however, with a careful choice of materials, one can design crucibles with extended lifetime and reduced contamination. This work reports some preliminary results we have obtained in the assessing of crucible materials and design, such as, graphite, Si C, vitreous carbon and Al{sub 2} O{sub 3}. (author) 1 refs., 3 figs.,2 tabs.

About Eddy Currents in Induction Melting Processes

Directory of Open Access Journals (Sweden)

Gafiţa Nicolae-Bogdan

2008-05-01

Full Text Available In this paper we present a method forcomputing the eddy currents in induction meltingprocesses for non-ferrous alloys. We take intoconsideration the situation when only the crucible ismoving, inside the coils. This fact makes differentialcomputation methods to be hard to apply, because isnecessary to generate a new mesh and a new systemmatrix for every for every new position of the cruciblerelated to the coils. Integral methods cancel thisdrawback because the mesh is generated only for thedomains with eddy currents. For integral methods, themesh and the inductance matrix remain unchangedduring the movement of the crucible; only the free termsof the equation system will change.

HIGHLY REFRACTORY CRUCIBLES OF STABILIZED ZIRCONIA FOR INDUCTION MELTING OF THE PLATINUM GROUP METALS, FABRICATED BY VIBROCASTING

OpenAIRE

V. V. Primachenko; V. V. Martynenko; I. G. Szulik; I. A. Kushchenko

2012-01-01

As the result of the studies at PJSC « UKRNIIO them. A.S.Berezhnogo» the technology and commercial production of crucibles from stabilized zirconia for the smelting of platinum group metals are develop

50-kg large-size cold crucible levitation melting apparatus; Teibu shuto kino wo motsu 50kg kyu korudo kurushiburu fuyo yokai shochi no kaihatsu

Energy Technology Data Exchange (ETDEWEB)

Hayashi, S. [Fuji Electric Co. Ltd., Tokyo (Japan); Tadano, E. [Fuji Electric Corporate Research and Development Ltd., Kanagawa (Japan)

1997-06-25

With an increase in the degree of industrial techniques and the development of high-technology products in recent years, it has been demanded that the quality of high-purity metal materials be improved. The levitation melting method is a new melting method in which a metal material is melted by induction heating while the material is levitated in a water-cooled copper crucible. This paper made clear the principle of the levitation melting method and describes some problems in the development of a 50 kg-class large-capacity levitation melting apparatus and solutions to the problems. The development of a 50 kg-class levitation melting apparatus having a bottom discharging function was carried out on the basis of the results of discussion of the above-mentioned problems, and the noncontact melting of 50 kg cast iron and the noncontact bottom discharging of molten iron succeeded. This enabled the noncontact process of from the melting of a high-purity metal material and a metal of a high melting point to the casting of the molten metal. Since a continuous casting apparatus is provided under the crucible, the casting of an ingot and a rod material becomes possible. When a metal material is levitation-melted in superhigh vacuum, production of a superhigh-purity metal and a new metal material can be attained since the material is not contaminated by the atmosphere. 9 refs., 11 figs., 4 tabs.

HIGHLY REFRACTORY CRUCIBLES OF STABILIZED ZIRCONIA FOR INDUCTION MELTING OF THE PLATINUM GROUP METALS, FABRICATED BY VIBROCASTING

Directory of Open Access Journals (Sweden)

V. V. Primachenko

2012-01-01

Full Text Available As the result of the studies at PJSC « UKRNIIO them. A.S.Berezhnogo» the technology and commercial production of crucibles from stabilized zirconia for the smelting of platinum group metals are develop

Certain physicochemical characteristics of Bi1.4Y0.6O3 prepared by the method of direct high-frequency fusion in cold crucible

International Nuclear Information System (INIS)

Poluyan, A.F.; Lashneva, V.V.; Vecher, A.A.; Voropaev, A.G.; Savitskij, A.A.; Tatarintsev, V.M.

1988-01-01

Electric properties and the nature of conductivity of Bi 1.4 V 0.6 O 3 solid solution prepared by the method of direct high-frequency melting in the cold crucible are studied. A sample of Bi 1.4 Y 0.6 O 3 composition synthesized by this technique has a higher electric conductivity value as compared with analogous polycrystal sample has a cubic face-centered structure of the τ-Bi 2 O 3 type. On the basis of experimental e.m.f. values temperature dependences of pressures of oxygen dissociation for Bi 2 O 3 and Bi 1.4 Y 0.6 O 3 are calculated. Bi 1.4 Y 0.6 O 3 solid solution has lower values of Po 2 dissociation pressure as compared with bismuth oxide. This expands the limits of its application

Covering a Crucible with Metal Containing Channels

Science.gov (United States)

Grugel, Richard N.

2006-01-01

In a procedure that partly resembles the lost-wax casting process, a crucible made of a brittle material (ceramic, quartz, or glass) is covered with a layer of metal containing channels. The metal cover and the channels can serve any or all of several purposes, depending upon the application: Typically, the metal would serve at least partly to reinforce the crucible. The channels could be used as passages for narrow objects that could include thermocouples and heat-transfer strips. Alternatively or in addition, channels could be used as flow paths for liquid or gaseous coolants and could be positioned and oriented for position- or direction-selective cooling. In some cases, the channels could be filled with known gases and sealed so that failure of the crucibles could be indicated by instruments that detect the gases. The process consists of three main steps. In the first step, a pattern defining the channels is formed by wrapping or depositing a material in the desired channel pattern on the outer surface of the crucible. The pattern material can be a plastic, wax, low-ash fibrous material, a soluble material, or other suitable material that can subsequently be removed easily. In a proof-of-concept demonstration (see figure), the crucible was an alumina cylinder and the mold material was plastic tie-down tape. In the second step, the patterned crucible is coated with metal. In one variation of the second step, a very thin layer containing or consisting of an electrically conductive material (e.g., gold, silver, or carbon) is painted or otherwise deposited on the mold-covered crucible, then the covering metal required for the specific application is electrodeposited on the very thin conducting layer. In another variation of the second step, the metal coat is formed by chemical vapor deposition. In the proof-of-concept demonstration, a layer of nickel 0.003 in. ( 0.08 mm) thick was electrodeposited. In the third step, the patterned material is removed. This is

Effect Of Turbulence Modelling In Numerical Analysis Of Melting Process In An Induction Furnace

Directory of Open Access Journals (Sweden)

Buliński P.

2015-09-01

Full Text Available In this paper, the velocity field and turbulence effects that occur inside a crucible of a typical induction furnace were investigated. In the first part of this work, a free surface shape of the liquid metal was measured in a ceramic crucible. Then a numerical model of aluminium melting process was developed. It took into account coupling of electromagnetic and thermofluid fields that was performed using commercial codes. In the next step, the sensitivity analysis of turbulence modelling in the liquid domain was performed. The obtained numerical results were compared with the measurement data. The performed analysis can be treated as a preliminary approach for more complex mathematical modelling for the melting process optimisation in crucible induction furnaces of different types.

Crucibles of Leadership.

Science.gov (United States)

Bennis, Warren G.; Thomas, Robert J.

2002-01-01

Often, a traumatic event that forces a profound redefinition of the self forges leadership. The stories of a diverse group of business leaders and the "crucible experiences" that shaped them reveal four essential skills: ability to engage others in shared meanings, compelling voice, integrity, and adaptive capacity (applied creativity). (SK)

Consolidation of simulated nuclear metallic waste by vacuum coreless induction melting

International Nuclear Information System (INIS)

Montgomery, D.R.

1984-10-01

Vacuum coreless induction melting with bottom pouring has exceeded expectations for simplicity, reliability, and versatility when melting the zirconium and iron eutectic alloy. The melting tests have established that: the eutectic mixture of oxidized Zircaloy 4 hulls mixed with Type 316 stainless steel hulls can be melted at 41 kg/h at 40 kW with a power consumption of 1.03 kWh/kg and a melting temperature of 1260 0 C; the life of a graphite crucible can be expected to be longer by a factor of 4 than was previously projected; the bottom-pour water-cooled copper freeze plug was 100% reliable; a 24-in.-tall stainless steel canister with 1/4-in.-thick walls (6-in. inside diameter) was satisfactory in every respect; an ingot formed from 4 consecutive heats poured into a stainless steel canister appeared to be approx. 99% dense after sectioning; preplaced scrap in the canister can be encapsulated with molten metal to about 99% density; large pieces of Zircaloy 4 and stainless steel scrap can be melted, but have differing melting parameters; the pouring nozzle requires further development to prevent solidified drops from forming at the hole exit after a pour. It is recommended that a large-scale cold mock-up facility be established to refine and test a full-scale vacuum coreless induction melting system. Other options might include further scaled-down experiments to test other alloys and crucible materials under different atmospheric conditions (i.e., air melting). 1 reference, 18 figures, 1 table

Slip cast coating of alumina crucibles

International Nuclear Information System (INIS)

Haroun, N.A.; El-Masry, M.A.A.

1980-01-01

The development of a process for coating alumina crucibles with MgO protective coat in a two-step slip casting operation is described. The best milling conditions for the alumina used were wet ball milling for 24 hr. MgO had to be calcined at 1200 0 C to minimize hydration. Optimum slip casting conditions for alumina and magnesia were found to be L/S I and pH 3-6 or 9-II for the former, and L/S 3 (alcohol) and pH 8.5-10 for the latter. Sintering of Al 2 O 3 and MgO in the temperature range 1150-500 0 C was investigated. Additions of NiO and MgO lowered the sintered densities at lower temperatures but improved the densification at 1500 0 C. Near theoretical density Al 2 O 3 and MgO crucibles were obtained. A two-step slip casting technique was developed to coat Al 2 O 3 with MgO. Certain slow firing schedules could eliminate the otherwise observed coat-crucible separation and cracks. (author)

Alternative Crucibles for U-Mo Microwave Melting

Energy Technology Data Exchange (ETDEWEB)

Kirby, Brent W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2017-03-31

The crucibles used currently for microwave melting of U-Mo alloy at the Y-12 Complex contain silicon carbide (SiC) in a mullite (3Al₂O₃-2SiO₂) matrix with an erbia coating in contact with the melt. Due to observed silicon contamination, Pacific Northwest National Laboratory has investigated alternative crucible materials that are susceptible to microwave radiation and are chemically compatible with molten U-Mo at 1400 1500C. Recommended crucibles for further testing are: 1) high-purity alumina (Al₂O₃); 2) yttria-stabilized zirconia (ZrO₂); 3) a composite of alumina and yttria-stabilized zirconia; 4) aluminum nitride (AlN). Only AlN does not require an erbia coating. The recommended secondary susceptor, for heating at low temperature, is SiC in a “picket fence” arrangement.

Numerical analysis of continuous charge of lithium niobate in a double-crucible Czochralski system using the accelerated crucible rotation technique

Science.gov (United States)

Kitashima, Tomonori; Liu, Lijun; Kitamura, Kenji; Kakimoto, Koichi

2004-05-01

The transport mechanism of supplied raw material in a double-crucible Czochralski system using the accelerated crucible rotation technique (ACRT) was investigated by three-dimensional and time-dependent numerical simulation. The calculation clarified that use of the ACRT resulted in enhancement of the mixing effect of the supplied raw material. It is, therefore, possible to maintain the composition of the melt in an inner crucible during crystal growth by using the ACRT. The effect of the continuous charge of the raw material on melt temperature was also investigated. Our results showed that the effect of feeding lithium niobate granules on melt temperature was small, since the feeding rate of the granules is small. Therefore, solidification of the melt surface due to the heat of fusion in this system is not likely.

Conditioning processes for incinerator ashes

International Nuclear Information System (INIS)

Jouan, A.; Ouvrier, N.; Teulon, F.

1990-01-01

Three conditioning processes for alpha-bearing solid waste incineration ashes were investigated and compared according to technical and economic criteria: isostatic pressing, cold-crucible direct-induction melting and cement-resin matrix embedding

Induction of proliferation of basal epidermal keratinocytes by cold atmospheric-pressure plasma.

Science.gov (United States)

Hasse, S; Duong Tran, T; Hahn, O; Kindler, S; Metelmann, H-R; von Woedtke, T; Masur, K

2016-03-01

Over the past few decades, new cold plasma sources have been developed that have the great advantage of operating at atmospheric pressure and at temperatures tolerable by biological material. New applications for these have emerged, especially in the field of dermatology. Recently it was demonstrated that cold atmospheric-pressure plasma positively influences healing of chronic wounds. The potential of cold plasma lies in its capacity to reduce bacterial load in the wound while at the same time stimulating skin cells and therefore promoting wound closure. In recent years, there have been great advances in the understanding of the molecular mechanisms triggered by cold plasma involving signalling pathways and gene regulation in cell culture. To investigate cold plasma-induced effects in ex vivo treated human skin biopsies. Human skin tissue was exposed to cold plasma for different lengths of time, and analysed by immunofluorescence with respect to DNA damage, apoptosis, proliferation and differentiation markers. After cold plasma treatment, the epidermal integrity and keratin expression pattern remained unchanged. As expected, the results revealed an increase in apoptotic cells after 3 and 5 min of treatment. Strikingly, an induction of proliferating basal keratinocytes was detected after cold plasma exposure for 1 and 3 min. As these are the cells that regenerate the epidermis, this could indeed be beneficial for wound closure. We investigated the effect of cold plasma on human skin by detecting molecules for growth and apoptosis, and found that both processes are dependent on treatment time. Therefore, this approach offers promising results for further applications of cold plasma in clinical dermatology. © 2015 British Association of Dermatologists.

Evaluation of AS-CAST U-Mo alloys processed in graphite crucible coated with boron nitride

Energy Technology Data Exchange (ETDEWEB)

Marra, Kleiner M., E-mail: kleiner.marra@prof.una.br [Centro Universitario UNA, Belo Horizonte, MG (Brazil). Curso de Engenharia Mecânica; Reis, Sérgio C.; Paula, João B. de; Pedrosa, Tércio A., E-mail: reissc@cdtn.br, E-mail: jbp@cdtn.br, E-mail: tap@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

2017-07-01

This paper reports the production of uranium-molybdenum alloys, which have been considered promising fuel for test and research nuclear reactors. U-Mo alloys were produced in three molybdenum contents: 5w%, 7w%, and 10w%, using an electric vacuum induction furnace. A boron nitride-coated graphite crucible was employed in the production of the alloys and, after melting, the material was immediately poured into a boron nitride-coated graphite mold. The incorporation of carbon was observed, but it happened in a lower intensity than in the case of the non-coated crucible/mold. It is observed that the carbon incorporation increased and alloys density decreased with Mo addition. It was also noticed that the increase in the carbon or molybdenum content did not seem to change the as-cast structure in terms of granulation. The three alloys presented body-centered cubic crystal structure (γ-phase), after solidification, besides a seeming negative microsegregation of molybdenum, from the center to the periphery of the grains. There were signs of macrosegregation, from the base to the top of the ingots. (author)

Energy Savings Through Thermally Efficient Crucible Technology: Fundamentals, Process Modeling, and Applications

Science.gov (United States)

Shi, Wenwu; Pinto, Brian

2017-12-01

Melting and holding molten metals within crucibles accounts for a large portion of total energy demand in the resource-intensive nonferrous foundry industry. Multivariate mathematical modeling aided by detailed material characterization and advancements in crucible technologies can make a significant impact in the areas of cost-efficiency and carbon footprint reduction. Key thermal properties such as conductivity and specific heat capacity were studied to understand their influence on crucible furnace energy consumption during melting and holding processes. The effects of conductivity on thermal stresses and longevity of crucibles were also evaluated. With this information, accurate theoretical models using finite element analysis were developed to study total energy consumption and melting time. By applying these findings to recent crucible developments, considerable improvements in field performance were reported and documented as case studies in applications such as aluminum melting and holding.

The Suitability Of Local Quartz Sand In The Production Of Bath Crucibles.

Directory of Open Access Journals (Sweden)

C. O. Okpanachi

2017-03-01

Full Text Available The suitability of local quartz sand in the production of bath crucibles is a study that was carried out in order to impart overall strength on bath crucibles hence reduce breakages during fettling. Therefore this research constitutes a study to enhance the efficiency of production of bath crucibles by addition of quartz sand in slip preparation. The steps taken in the beneficiation of quartz sand for the production of bath crucibles are comminution which entails crushing and milling classification washing liquid dispersion sizing and reduction of iron content by magnetic separation. The slip contains materials like plastic clay feldspar kaolin talc sodium silicate water quartz sand etc. These were all milled in the ball mill for slip production casting and fettling glazing and sintering to get final bath crucibles as the end products. Quartz sand is used in a variety of products essentially as raw material for the foundry casting and glass industries and also in chemicals water filtration and ceramics the heat resistance nature of quartz sand makes it an excellent refractory substance for these industrial processes. Slip can be prepared for production of bath crucibles without the inclusion of quartz sand however the addition of quartz sand is needed to improve the mechanical performance of the slip in the production of bath crucibles.

A multi-crucible core-catcher concept: Design considerations and basic results

International Nuclear Information System (INIS)

Szabo, I.

1995-01-01

A multi-crucible core-catcher concept to be implemented in new light water reactor containments has recently been proposed. This paper deals with conceptual design considerations and the various ways this type of core-catcher could be designed to meet requirements for reactor application. A systematic functional analysis of the multi-crucible core-catcher concept and the results of the preliminary design calculation are presented. Finally, the adequacy of the multi-crucible core-catcher concept for reactor application is discussed. (orig.)

Numerical study of particle filtration in an induction crucible furnace

International Nuclear Information System (INIS)

Asad, Amjad; Kratzsch, Christoph; Dudczig, Steffen; Aneziris, Christos G.; Schwarze, Rüdiger

2016-01-01

Highlights: • Removing particles from a melt in an induction furnace by using a filter is introduced. • The effect of filter and its permeability on the melt flow is shown. • The impact of filter permeability and particle diameter on filter efficiency is studied. • The filter efficiency depends on filter position and number of the used filter. - Abstract: The present paper deals with a numerical investigation of the turbulent melt flow driven by the electromagnetic force in an induction furnace. The main scope of the paper is to present a new principle to remove non-metallic particles from steel melt in an induction furnace by immersing a porous filter in the melt. The magnetic field acting on the melt is calculated by using the open source software MaxFEM"®, while the turbulent flow is simulated by means of the open source computational fluid dynamics library OpenFOAM"®. The validation of the numerical model is accomplished by using experimental results for the flow without the immersed filter. Here it is shown that the time-averaged flow, obtained numerically is in a good quantitive agreement with the experimental data. Then, the validated numerical model is employed to simulate the melt flow with the immersed filter in the induction furnace of a new type of real steel casting simulator investigated at Technische Universität Bergakademie Freiberg. The considerable effect of the filter on the flow pattern is indicated in the present work. Moreover, it is shown that the filter permeability and its position have a significant influence on the melt flow in the induction furnace. Additionally, particles are injected in the flow domain and tracked by using Lagrangian framework. In this case, the efficiency of the used filter is determined in the present investigation depending on its permeability, its position and the particles diameter.

Role of crucible partition in improving Czochralski melt conditions

Science.gov (United States)

Jafri, I. H.; Prasad, V.; Anselmo, A. P.; Gupta, K. P.

1995-09-01

Many of the inhomogeneities and defects in the crystal grown from a pool of melt are because of the inherent unsteady growth kinetics and flow instabilities of the process. A scaled up version of the Czochralski process induces oscillatory and turbulent conditions in the melt, thereby resulting in the production of non-uniform silicon crystals. This numerical study reveals that a crucible partition shorter than the melt height can significantly improve the melt conditions. The obstruction at the bottom of the crucible is helpful but the variations in heat flux and flow patterns remain random. However, when the obstruction is introduced at the top of the melt, the flow conditions become much more desirable and oscillations are greatly suppressed. It is also found that a full-melt height partition or a double-crucible may not be a good choice. An optimal size of the blockage and its location to produce the most desirable process conditions will depend on the growth parameters including the melt height and the crucible diameter. These findings should be particularly useful in designing a solid polysilicon pellets-feed continuous Czochralski process for Si crystals.

Cermet crucible for metallurgical processing

Science.gov (United States)

Boring, Christopher P.

1995-01-01

A cermet crucible for metallurgically processing metals having high melting points comprising a body consisting essentially of a mixture of calcium oxide and erbium metal, the mixture comprising calcium oxide in a range between about 50 and 90% by weight and erbium metal in a range between about 10 and 50% by weight.

Wootz: Erroneous Transliteration of Sanskrit " Utsa" used for Indian Crucible Steel

Science.gov (United States)

Dube, R. K.

2014-11-01

The terminology Wootz for the legendary Indian crucible steel was first introduced by Helenus Scott in his letter to Joseph Banks, the then President of the Royal Society, London, in 1794. He stated several salient features of this steel in his letter. During the period 1794-1796, Banks received approximately 200 lbs. of this steel from Scott. Banks assigned several professionals to carry out experimental work on Indian crucible steel. One such important person was the famous surgical instrument maker, cutler and metallurgist of his time, James Stodart. Stodart experimented extensively with the Indian crucible steel, and was its great admirer. It has been shown, along with corroborative documentary evidence, that the original word for this steel was Sanskrit word " utsa". This was erroneously transliterated in Roman script as Wootz by Scott in his letter to Banks. It was James Stodart, who preserved the Sanskrit word " utsa" written in Devanāgarī script on his trade card for future generation. The reason for using this word for the Indian crucible steel has also been discussed.

Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins.

Science.gov (United States)

Fujita, Takanori; Liu, Yu; Higashitsuji, Hiroaki; Itoh, Katsuhiko; Shibasaki, Koji; Fujita, Jun; Nishiyama, Hiroyuki

2018-01-01

Cold-inducible RNA-binding protein (CIRP), RNA-binding motif protein 3 (RBM3) and serine and arginine rich splicing factor 5 (SRSF5) are RNA-binding proteins that are transcriptionally upregulated in response to moderately low temperatures and a variety of cellular stresses in mammalian cells. Induction of these cold-inducible proteins (CIPs) is dependent on transient receptor potential (TRP) V4 channel protein, but seems independent of its ion channel activity. We herein report that in addition to TRPV4, TRPV3 and TRPM8 are necessary for the induction of CIPs. We established cell lines from the lung of TRPV4-knockout (KO) mouse, and observed induction of CIPs in them by western blot analysis. A TRPV4 antagonist RN1734 suppressed the induction in wild-type mouse cells, but not in TRPV4-KO cells. A TRPV3 channel blocker S408271 and a TRPM8 channel blocker AMTB as well as siRNAs against TRPV3 and TRPM8 suppressed the CIP induction in mouse TRPV4-KO cells and human U-2 OS cells. A TRPV3 channel agonist 2-APB induced CIP expression, but camphor did not. Neither did a TRPM8 channel agonist WS-12. These results suggest that TRPV4, TRPV3 and TRPM8 proteins, but not their ion channel activities are necessary for the induction of CIPs at 32 °C. Identification of proteins that differentially interact with these TRP channels at 37 °C and 32 °C would help elucidate the underlying mechanisms of CIP induction by hypothermia. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Effect of the roughness of crucible on viscosity of liquid Pb38.1Sn61.9 alloy

International Nuclear Information System (INIS)

Wu Yuqin; Bian Xiufang; Mao Tan; Li Xuelian; Li Taibao; Wang Caidong

2007-01-01

The viscosity of the eutectic Pb 38.1 Sn 61.9 alloy has been measured by a torsional oscillation viscometer using three different crucibles which are made of the materials of highly sintered alumina (Al 2 O 3 ), quartz (SiO 2 ), and graphite (C) respectively. The roughness of crucibles has effect on the viscosity. The viscosity data obtained for SiO 2 and C crucibles were concentrated in the narrow range of about 0.5% and showed almost the same activation energy. However, the viscosity obtained using Al 2 O 3 crucible with the maximal roughness is higher than that using the other two crucibles. The discrepancy of viscosity obtained using those crucibles increases with the viscosity. In addition, the viscosity obtained using three kinds of crucibles in our work has a breakpoint at 488 K, which is approximate with the results of electrical conductivity and thermopower measurements reported by Plevachuk et al., which indicates the microstructure in melt changes before solidification

Making rhyolite in a basalt crucible

Science.gov (United States)

Eichelberger, John

2016-04-01

Iceland has long attracted the attention of those concerned with the origin of rhyolitic magmas and indeed of granitic continental crust, because it presents no alternative for such magmas other than deriving them from a basaltic source. Hydrothermally altered basalt has been identified as the progenitor. The fact that rhyolite erupts as pure liquid requires a process of melt-crustal separation that is highly efficient despite the high viscosity of rhyolite melt. Volcanoes in Iceland are foci of basaltic magma injection along the divergent plate boundary. Repeated injection produces remelting, digestion, and sometimes expulsion or lateral withdrawal of material resulting in a caldera, a "crucible" holding down-dropped and interlayered lava flows, tephras, and injected sills. Once melting of this charge begins, a great deal of heat is absorbed in the phase change. Just 1% change in crystallinity per degree gives a melt-present body an effective heat capacity >5 times the subsolidus case. Temperature is thus buffered at the solidus and melt composition at rhyolite. Basalt inputs are episodic ("fires") so likely the resulting generation of rhyolite by melting is too. If frequent enough to offset cooling between events, rhyolite melt extractions will accumulate as a rhyolite magma reservoir rather than as discrete crystallized sills. Evidently, such magma bodies can survive multiple firings without themselves erupting, as the 1875 eruption of Askja Caldera of 0.3 km3 of rhyolite equilibrated at 2-km depth without previous leakage over a ten-millennium period and the surprise discovery of rhyolite magma at 2-km depth in Krafla suggest. Water is required for melting; otherwise melting cannot begin at a temperature lower than that of the heat source. Because the solubility of water in melt is pressure-dependent and almost zero at surface pressure, there must be a minimum depth at which basalt-induced melting can occur and a rhyolite reservoir sustained. In practice, the

CRUCIBLE TESTING OF TANK 48 RADIOACTIVE WASTE SAMPLE USING FBSR TECHNOLOGY FOR ORGANIC DESTRUCTION

International Nuclear Information System (INIS)

Hammond, C; William Pepper, W

2008-01-01

The purpose of crucible scale testing with actual radioactive Tank 48H material was to duplicate the test results that had been previously performed on simulant Tank 48H material. The earlier crucible scale testing using simulants was successful in demonstrating that bench scale crucible tests produce results that are indicative of actual Fluidized Bed Steam Reforming (FBSR) pilot scale tests. Thus, comparison of the results using radioactive Tank 48H feed to those reported earlier with simulants would then provide proof that the radioactive tank waste behaves in a similar manner to the simulant. Demonstration of similar behavior for the actual radioactive Tank 48H slurry to the simulant is important as a preliminary or preparation step for the more complex bench-scale steam reformer unit that is planned for radioactive application in the Savannah River National Laboratory (SRNL) Shielded Cells Facility (SCF) later in 2008. The goals of this crucible-scale testing were to show 99% destruction of tetraphenylborate and to demonstrate that the final solid product produced is sodium carbonate. Testing protocol was repeated using the specifications of earlier simulant crucible scale testing, that is sealed high purity alumina crucibles containing a pre-carbonated and evaporated Tank 48H material. Sealing of the crucibles was accomplished by using an inorganic 'nepheline' sealant. The sealed crucibles were heat-treated at 650 C under constant argon flow to inert the system. Final product REDOX measurements were performed to establish the REDuction/OXidation (REDOX) state of known amounts of added iron species in the final product. These REDOX measurements confirm the processing conditions (pyrolysis occurring at low oxygen fugacity) of the sealed crucible environment which is the environment actually achieved in the fluidized bed steam reformer process. Solid product dissolution in water was used to measure soluble cations and anions, and to investigate insoluble

Numerical Research on Magnetic Field, Temperature Field and Flow Field During Melting and Directionally Solidifying TiAl Alloys by Electromagnetic Cold Crucible

Science.gov (United States)

Chen, Ruirun; Yang, Yaohua; Gong, Xue; Guo, Jingjie; Su, Yanqing; Ding, Hongsheng; Fu, Hengzhi

2017-12-01

The electromagnetic cold crucible (EMCC) technique is an effective method to melt and directionally solidify reactive and high-temperature materials without contamination. The temperature field and fluid flow induced by the electromagnetic field are very important for melting and controlling the microstructure. In this article, a 3D EMCC model for calculating the magnetic field in the charges (TiAl alloys) using the T-Ω finite element method was established and verified. Magnetic fields in the charge under different electrical parameters, positions and dimensions of the charge were calculated and analyzed. The calculated results show that the magnetic field concentrates in the skin layer, and the magnetic flux density ( B) increases with increasing of the frequency, charge diameter and current. The maximum B in the charge is affected by the position of the charge in EMCC ( h 1) and the charge height ( h 2), which emerges at the middle of coils ( h c) when the relationship of h c < h 1 + h 2 < h c + δ is satisfied. Lower frequency and smaller charge diameter can improve the uniformity of the magnetic field in the charge. Consequently, the induced uniform electromagnetic stirring weakens the turbulence and improves temperature uniformity in the vicinity of the solid/liquid (S/L) interface, which is beneficial to forming a planar S/L interface during directional solidification. Based on the above conclusions, the TiAlNb alloy was successfully melted with lower power consumption and directionally solidified by the square EMCC.

Fabrication technique of U-siliscide solution crucible

Energy Technology Data Exchange (ETDEWEB)

Cho, Chull Koo; Kim, Joon Soo; Ha, Ho Gwan; Kang, Hwan Gui; Kim, Jung Goo; Yun, Jong Yong [Dongsuh Ceramic Institute, Seoul (Korea, Republic of)

1997-07-01

The objective of this study is to establish ZrO{sub 2} crucibel fabrication technology preventing the infiltration by foreign substances. This study was established and practiced technology of formation and sintering of dense zirconia crucible was established at the second year. 21 refs., 10 tabs., 21 figs. (author)

Reproducing crucible steel: a practical guide and a comparative analysis to persian manuscripts

Directory of Open Access Journals (Sweden)

Moshtagh Khorasani, Manouchehr

2013-12-01

Full Text Available Different terms are used in old Persian manuscripts, such as Ta’id Besârat, to define and refer to crucible or watered steel and different types of swords. However, there are few manuscripts that describe the way crucible steel cakes and blades were made such as the manuscript Gŏharnâme. The present article deals with the making of crucible steel as described in Persian manuscripts and also with a new reproduction process of making crucible steel as conducted by the Finnish smith Niko Hynninen.Los antiguos manuscritos persas, tales como Ta’id Besârat, emplean diversos términos para definir y referirse al acero de crisol o acero de Damasco y a diversos tipos de espada. Sin embargo, existen pocos manuscritos que describan el modo en que se elaboraban los lingotes y hojas de acero de crisol, entre ellos el manuscrito Gŏharnâme. El presente artículo describe el proceso de elaboración del acero de crisol tal y como lo refieren los manuscritos persas, así como una moderna reproducción del mismo realizada por el forjador finlandés Niko Hynninen.

Vacuum-induction melting, refining, and casting of uranium and its alloys

Energy Technology Data Exchange (ETDEWEB)

Jackson, R J

1989-10-11

The vacuum-induction melting (VIM), refining, and casting of uranium and its alloys are discussed. Emphasis is placed on historical development, VIM equipment, crucible and mold design, furnace atmospheres, melting parameters, impurity pickup, ingot quality, and economics. The VIM procedures used to produce high-purity, high-quality sound ingots at the US Department of Energy Rocky Flats Plant are discussed in detail.

Influence of Crucible Thermal Conductivity on Crystal Growth in an Industrial Directional Solidification Process for Silicon Ingots

Directory of Open Access Journals (Sweden)

Zaoyang Li

2016-01-01

Full Text Available We carried out transient global simulations of heating, melting, growing, annealing, and cooling stages for an industrial directional solidification (DS process for silicon ingots. The crucible thermal conductivity is varied in a reasonable range to investigate its influence on the global heat transfer and silicon crystal growth. It is found that the crucible plays an important role in heat transfer, and therefore its thermal conductivity can influence the crystal growth significantly in the entire DS process. Increasing the crucible thermal conductivity can shorten the time for melting of silicon feedstock and growing of silicon crystal significantly, and therefore large thermal conductivity is helpful in saving both production time and power energy. However, the high temperature gradient in the silicon ingots and the locally concave melt-crystal interface shape for large crucible thermal conductivity indicate that high thermal stress and dislocation propagation are likely to occur during both growing and annealing stages. Based on the numerical simulations, some discussions on designing and choosing the crucible thermal conductivity are presented.

Induction skull melting facility: an advanced system for electromagnetic processing of metals and alloys

International Nuclear Information System (INIS)

Sugilal, G.; Agarwal, K.

2017-01-01

Induction Skull Melting (ISM) is an advanced technology for processing highly refractory and extremely reactive metals and their alloys to produce ultra-high purity products. In ISM, the metallic charge is melted in a water-cooled, copper crucible. The crucible is segmented so that the magnetic field can penetrate into the metallic charge to be melted. By virtue of the strong electromagnetic stirring, the ISM technology can also be used to homogenize alloys of metals, which are difficult to be combined uniformly in composition due to large difference in specific gravity. In view of various important applications in frontier areas of material research, development and production, Bhabha Atomic Research Centre developed the ISM technology indigenously

CRUCIBLE TESTING OF TANK 48H RADIOACTIVE WASTE SAMPLE USING FLUIDIZED BED STEAM REFORMING TECHNOLOGY FOR ORGANIC DESTRUCTION

International Nuclear Information System (INIS)

Crawford, C

2008-01-01

The purpose of crucible scale testing with actual radioactive Tank 48H material was to duplicate the test results that had been previously performed on simulant Tank 48H material. The earlier crucible scale testing using simulants was successful in demonstrating that bench scale crucible tests produce results that are indicative of actual Fluidized Bed Steam Reforming (FBSR) pilot scale tests. Thus, comparison of the results using radioactive Tank 48H feed to those reported earlier with simulants would then provide proof that the radioactive tank waste behaves in a similar manner to the simulant. Demonstration of similar behavior for the actual radioactive Tank 48H slurry to the simulant is important as a preliminary or preparation step for the more complex bench-scale steam reformer unit that is planned for radioactive application in the Savannah River National Laboratory (SRNL) Shielded Cells Facility (SCF) later in 2008. The goals of this crucible-scale testing were to show 99% destruction of tetraphenylborate and to demonstrate that the final solid product produced is sodium carbonate. Testing protocol was repeated using the specifications of earlier simulant crucible scale testing, that is sealed high purity alumina crucibles containing a pre-carbonated and evaporated Tank 48H material. Sealing of the crucibles was accomplished by using an inorganic 'nepheline' sealant. The sealed crucibles were heat-treated at 650 C under constant argon flow to inert the system. Final product REDOX measurements were performed to establish the REDuction/OXidation (REDOX) state of known amounts of added iron species in the final product. These REDOX measurements confirm the processing conditions (pyrolysis occurring at low oxygen fugacity) of the sealed crucible environment which is the environment actually achieved in the fluidized bed steam reformer process. Solid product dissolution in water was used to measure soluble cations and anions, and to investigate insoluble

Ceramic Materials Selection of Fuel Crucibles based on Plasma Spray Coating for SFR

Energy Technology Data Exchange (ETDEWEB)

Song, Hoon; Kim, Jonghwan; Kim, Hyungtae; Ko, Youngmo; Woo, Yoonmyung; Oh, Seokjin; Kim, Kihwan; Lee, Chanbock [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2012-07-01

The plasma-sprayed coating can provide the crucible with a denser, more friable coating layer, compared with the more friable coating layer formed by slurry-coating, which was used to prevent the interaction between melt and crucibles. Plasma-sprayed coatings are consolidated by mechanical interlocking of the molten particles impacting on the substrate and are dense by the heat applied by the plasma. The increased coating density is advantageous because it should not require frequent re coating and U-Zr melt penetration through the protective layer is more difficult in a dense coating than in a porous coating. In this study, we used Vacuum Plasma Spray method to investigate permanent coatings for re-usable crucibles for melting and casting of metallic fuel onto niobium substrates. Niobium was selected as a substrate because of its refractory nature and the coefficient of thermal expansion is similar to that of many of the candidate materials. After the HfC, ZrC, TiC, TaC, Y{sub 2}O{sub 3}, and 8% YSZ coatings were applied the resulting microstructure and chemical compositions was characterized to find the optimum process conditions for coating. Thermal plasma-sprayed coatings of refractory materials can be applied to develop a re-usable crucible coating for metallic fuel, such as the U-Zr alloy proposed for sodium cooled fast reactors.

Investigation of Reusable Crucibles on Uranium Casting by Injection Method

International Nuclear Information System (INIS)

Song, Hoon; Kim, Jong-Hwan; Ko, Young-Mo; Woo, Yoon-Myung; Kim, Ki-Hwan; Lee, Chan-Bock

2014-01-01

Slurry applied coatings must be recoated after every batch. Thermal plasma-sprayed coatings of refractory materials can be applied to develop a re-usable crucible coating for metallic fuel. Plasma-sprayed coating can provide a crucible with a denser, more durable, coating layer, compared with the more friable coating layer formed by slurry-coating. Plasma-sprayed coatings are consolidated by mechanical interlocking of the molten particles impacting on the substrate and are dense from the heat applied by the plasma. Although the protective layer is more difficult in a dense coating than in a porous coating, the increased coating density is advantageous because it should not require frequent recoating or U-Zr melt penetration. In this study, we used a Vacuum Plasma Spray (VPS) method, which is suitable to prevent oxidization and has a number of advantages such as low defect density and excellent adhesion of the coating layer, to investigate permanent coatings for re-usable crucibles for melting and casting of metallic fuel. After coatings, interaction studies between molten U-Zr alloys and the plasma sprayed coatings were also carried out. We summarized the results of the coating methods. All coated samples maintained good coating integrity in a U-Zr melt, but most of the coating method samples did not maintain integrity in the U-Zr-RE melt because of the cracks or microcracks of the coating layer, presumably formed from the thermal expansion difference. Only the TaC(100)-Y 2 O 3 (100) DL VPS coated rod survived the 2 cycles dipping test of U-Zr-RE melt. This is likely caused by good adhesion of the TaC coating onto the niobium rod and the chemical inertness of Y 2 O 3 coating material in the U-Zr-RE melt. Based on the results from the interactions with U-10Zr and U-10Zr-5RE melt, TaC(100)-Y 2 O 3 (100) plasma-sprayed coating methods have been applied to real graphite crucibles

Design of electrodes in geometrical control type electrolyzer for oxide electrowinning process

International Nuclear Information System (INIS)

Nobuo Okamura; Kenji Koizumi; Tadahiro Washiya; Shinnichi Aose

2005-01-01

Japan Nuclear Cycle Development Institute (JNC) has been developing a commercial scale electrolyzer with a throughput of 25 tHM/y for an oxide electrowinning process, a kind of pyrochemical reprocessing process. But it had some significant subjects to be solved before the application to a commercial reprocessing plant. The electrolyzer has some innovative characteristics, such as cold crucible induction melting (CCIM) technology and criticality safety control by shape of the vessel, in order to solve those subjects. These characteristics make a crucible narrow and deep. Therefore an arrangement of the internal components in the crucible is difficult. Two kinds of computer cords that evaluate the temperature distribution and the current density distribution were improved to help a design of the internal constitution. Finally, the internal constitution of the commercial scale electrolyzer was designed by using them in this study. (authors)

Ionic Conductivity and Air Stability of Al-Doped Li₇La₃Zr₂O₁₂ Sintered in Alumina and Pt Crucibles.

Science.gov (United States)

Xia, Wenhao; Xu, Biyi; Duan, Huanan; Guo, Yiping; Kang, Hongmei; Li, Hua; Liu, Hezhou

2016-03-02

Li7La3Zr2O12 (LLZO) is a promising electrolyte material for all-solid-state battery due to its high ionic conductivity and good stability with metallic lithium. In this article, we studied the effect of crucibles on the ionic conductivity and air stability by synthesizing 0.25Al doped LLZO pellets in Pt crucibles and alumina crucibles, respectively. The results show that the composition and microstructure of the pellets play important roles influencing the ionic conductivity, relative density, and air stability. Specifically, the 0.25Al-LLZO pellets sintered in Pt crucibles exhibit a high relative density (∼96%) and high ionic conductivity (4.48 × 10(-4) S cm(-1)). The ionic conductivity maintains 3.6 × 10(-4) S cm(-1) after 3-month air exposure. In contrast, the ionic conductivity of the pellets from alumina crucibles is about 1.81 × 10(-4) S cm(-1) and drops to 2.39 × 10(-5) S cm(-1) 3 months later. The large grains and the reduced grain boundaries in the pellets sintered in Pt crucibles are favorable to obtain high ionic conductivity and good air stability. X-ray photoelectron spectroscopy (XPS) and Raman spectroscopy results suggest that the formation of Li2CO3 on the pellet surface is probably another main reason, which is also closely related to the relative density and the amount of grain boundary within the pellets. This work stresses the importance of synthesis parameters, crucibles included, to obtain the LLZO electrolyte with high ionic conductivity and good air stability.

Modeling of velocity field for vacuum induction melting process

Institute of Scientific and Technical Information of China (English)

CHEN Bo; JIANG Zhi-guo; LIU Kui; LI Yi-yi

2005-01-01

The numerical simulation for the recirculating flow of melting of an electromagnetically stirred alloy in a cylindrical induction furnace crucible was presented. Inductive currents and electromagnetic body forces in the alloy under three different solenoid frequencies and three different melting powers were calculated, and then the forces were adopted in the fluid flow equations to simulate the flow of the alloy and the behavior of the free surface. The relationship between the height of the electromagnetic stirring meniscus, melting power, and solenoid frequency was derived based on the law of mass conservation. The results show that the inductive currents and the electromagnetic forces vary with the frequency, melting power, and the physical properties of metal. The velocity and the height of the meniscus increase with the increase of the melting power and the decrease of the solenoid frequency.

Multilayer Porous Crucibles for the High Throughput Salt Separation from Uranium Deposits

International Nuclear Information System (INIS)

Kwon, S. W.; Park, K. M.; Kim, J. G.; Kim, I. T.; Seo, B. K.; Moon, J. G.

2013-01-01

Solid cathode processing is necessary to separate the salt from the cathode since the uranium deposit in a solid cathode contains electrolyte salt. A physical separation process, such as a distillation separation, is more attractive than a chemical or dissolution process because physical processes generate much less secondary process. Distillation process was employed for the cathode processsing due to the advantages of minimal generation of secondary waste, compact unit process, simple and low cost equipment. The basis for vacuum distillation separation is the difference in vapor pressures between salt and uranium. A solid cathode deposit is heated in a heating region and salt vaporizes, while nonvolatile uranium remains behind. It is very important to increase the throughput of the salt separation system owing to the high uranium content of spent nuclear fuel and high salt fraction of uranium dendrites. The evaporation rate of the LiCl-KCl eutectic salt in vacuum distiller is not so high to come up with the generation capacity of uranium dendrites in an electro-refiner. Therefore, a wide evaporation area or high distillation temperature is necessary for the successful salt separation. In this study, it was attempted to enlarge a throughput of the salt distiller with a multilayer porous crucibles for the separation of adhered salt in the uranium deposits generated from the electrorefiner. The feasibility of the porous crucibles was tested by the salt distillation experiments. In this study, the salt distiller with multilayer porous crucibles was proposed and the feasibility of liquid salt separation was examined to increase a throughput. It was found that the effective separation of salt from uranium deposits was possible by the multilayer porous crucibles

Multilayer Porous Crucibles for the High Throughput Salt Separation from Uranium Deposits

Energy Technology Data Exchange (ETDEWEB)

Kwon, S. W.; Park, K. M.; Kim, J. G.; Kim, I. T.; Seo, B. K.; Moon, J. G. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2013-05-15

Solid cathode processing is necessary to separate the salt from the cathode since the uranium deposit in a solid cathode contains electrolyte salt. A physical separation process, such as a distillation separation, is more attractive than a chemical or dissolution process because physical processes generate much less secondary process. Distillation process was employed for the cathode processsing due to the advantages of minimal generation of secondary waste, compact unit process, simple and low cost equipment. The basis for vacuum distillation separation is the difference in vapor pressures between salt and uranium. A solid cathode deposit is heated in a heating region and salt vaporizes, while nonvolatile uranium remains behind. It is very important to increase the throughput of the salt separation system owing to the high uranium content of spent nuclear fuel and high salt fraction of uranium dendrites. The evaporation rate of the LiCl-KCl eutectic salt in vacuum distiller is not so high to come up with the generation capacity of uranium dendrites in an electro-refiner. Therefore, a wide evaporation area or high distillation temperature is necessary for the successful salt separation. In this study, it was attempted to enlarge a throughput of the salt distiller with a multilayer porous crucibles for the separation of adhered salt in the uranium deposits generated from the electrorefiner. The feasibility of the porous crucibles was tested by the salt distillation experiments. In this study, the salt distiller with multilayer porous crucibles was proposed and the feasibility of liquid salt separation was examined to increase a throughput. It was found that the effective separation of salt from uranium deposits was possible by the multilayer porous crucibles.

Definition and manufacture of vitreous matrices using innovative processes for the confinement of nuclear wastes or industrial toxic wastes

International Nuclear Information System (INIS)

Boen, R.; Ladirat, C.; Lacombe, J.

1997-01-01

Vitrification appears as a solution to toxic mineral waste confinement; this solution has been demonstrated at an industrial level for radioactive wastes. The utilization of cold crucible direct induction melting furnaces, associated to various waste pre-treatments and well-adapted gas processing, leads to the confinement of numerous toxic mineral wastes in a borosilicate vitreous matrix which quality and long term behaviour may be precisely defined

Using an induction melter with a cold crucible for the immobilization of plutonium

Energy Technology Data Exchange (ETDEWEB)

Kushnikov, V.V.; Matiunin, Yu.I.; Smelova, T.V. [A.A. Bochvara All Russian Scientific Research Institute of Non-Organic Materials, Moscow (Russian Federation)

1996-05-01

This report evaluates the possibilities for immobilizing weapons-grade plutonium in glass-type materials that satisfy requirements for eventual burial in deep geologic repositories and correspond to the standards set for spent fuel.

Design and Construction of Oil Fired Compact Crucible Furnace ...

African Journals Online (AJOL)

As a prelude to necessary industrialization, foundries are springing up in various parts of Nigeria and most of these foundries rely on oil fired furnaces in their operation. This study is aimed at developing an oil fired crucible furnace from locally sourced materials for foundries in Nigeria. In our design, a new system of fuel ...

Fission Product Release from Molten Pool: ceramic melt tests

Energy Technology Data Exchange (ETDEWEB)

Petrov, Yu.B.; Lopukh, D.B.; Petchenkov, A.Yu. [AO ' NP Sintez' , St. Petersburg (RU)] [and others

1999-07-01

Experimental results are presented on the volatilisation of UO{sub 2{+-}}{sub x}, SrO, BaO, CeO{sub 2} from corium melts. Corium melts were generated by high frequency induction melting in a cold crucible. The surface temperature of the melts was in the range from 1753 to 3023 K. Some results of the tests are discussed and a comparison with published data is made. (author)

Combined effects of crucible geometry and Marangoni convection on silicon Czochralski crystal growth

Energy Technology Data Exchange (ETDEWEB)

Mokhtari, F. [Unit of Developpement of Silicon Technologie, Algiers (Algeria); Bouabdallah, A.; Zizi, M. [LTSE Laboratory, University of Science and Technology USTHB., Babezzouar, Algiers (Algeria); Hanchi, S. [UER Mecanique/ E.M.P/ B.P, El Bahri/Alger (Algeria); Alemany, A. [Laboratoire EPM, CNRS, Grenoble (France)

2009-08-15

In order to understand the influence of crucible geometry combined with natural convection and Marangoni convection on melt flow pattern, temperature and pressure fields in silicon Czochralski crystal growth process, a set of numerical simulations was conducted. We carry out calculation enable us to determine temperature, pressure and velocity fields in function of Grashof and Marangoni numbers. The essential results show that the hemispherical geometry of crucible seems to be adapted for the growth of a good quality crystal and the pressure field is strongly affected by natural and Marangoni convection and it is more sensitive than temperature. (copyright 2009 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

Application of Ceramic Bond Coating for Reusable Melting Crucible of Metallic Fuel Slugs

Energy Technology Data Exchange (ETDEWEB)

Kim, Ki-Hwan; Song, Hoon; Ko, Young-Mo; Park, Jeong-Yong; Lee, Chan-Bock [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Hong, Ki-Won [Chungnam National University, Daejeon (Korea, Republic of)

2016-10-15

Metal fuel slugs of the driver fuel assembly have been fabricated by injection casting of the fuel alloys under a vacuum state or an inert atmosphere. Traditionally, metal fuel such as a U-Zr alloy system for SFR has been melted in slurry-coated graphite crucibles and cast in slurry-coated quartz tube molds to prevent melt/material interactions. Reactive coatings and porous coatings can be a source of melt contaminations, and fuel losses, respectively. Ceramic Y{sub 2}O{sub 3}, TiC, and TaC coating materials showed no penetration in the protective layer after a melt dipping test. However, the ceramic coating materials showed separations in the coating interface between the substrate and coating layer, or between the coating layer and fuel melt after the dipping test. All plasma-spray coated methods maintained a sound coating state after a dipping test with U-10wt.%Zr melt. A single coating Y{sub 2}O{sub 3}(150) layer and double coating layer of TaC(50)-Y{sub 2}O{sub 3}(100), showed a sound state or little penetration in the protective layer after a dipping test with U-10wt.%Zr-5wt.%RE melt. Injection casting experiments of U-10wt.%Zr and U-10wt.%Zr-5wt.%RE fuel slugs have been performed to investigate the feasibility of a reusable crucible of the metal fuel slugs. U–10wt.%Zr and U–10wt.%Zr–5wt.%RE fuel slugs have been soundly fabricated without significant interactions of the graphite crucibles. Thus, the ceramic plasma-spray coatings are thought to be promising candidate coating methods for a reusable graphite crucible to fabricate metal fuel slugs.

Commercialization project of Ulchin vitrification

International Nuclear Information System (INIS)

Jo, Hyun-Jun; Kim, Cheon-Woo; Hwang, Tae-Won

2011-01-01

The Ulchin Vitrification Facility (UVF), to be used for the vitirification of low- and intermediate-level radioactive waste (LILW) generated by nuclear power plants (NPPs), is the world's first commercial facility using Cold Crucible Induction Melter (CCIM) technology. The construction of the facility was begun in 2005 and was completed in 2007. From December 2007 to September 2009, all key performance tests, such as the system functional test, the cold test, the hot test, and the real waste test, were successfully carried out. The UVF commenced commercial operation in October 2009 for the vitrification of radioactive waste. (author)

Definition and preparation of glassy matrices by innovating processes to confine radioactive wastes and industrial toxic materials

International Nuclear Information System (INIS)

Moncouyoux, J.P.

1995-01-01

The confinement by vitrification of high-level radioactive wastes is studied in the CEA for fifteen years. These studies have lead to the preparation of glassy matrices by innovating processes. These processes can be applied to non-radioactive toxic materials treatment too. In this work are more particularly described the glassy matrix long-dated behaviour and the different vitrification processes used (by direct induction in cold crucible, by transferred arc plasma). (O.L.). 1 tab

Experimental research of crucible steel: a new insight and historical reflection

Directory of Open Access Journals (Sweden)

Klaas Remmen

2012-06-01

Full Text Available This paper describes experimental archaeo-metallurgical research on crucible steel, executed as a master project to obtain the master degree in conservation.  After evaluating the results of different manufacturing techniques, the so-called Georgian crucible steel technique showed results that were remarkably similar to archaeological evidence from Merv, Turkmenistan. An objective historical reflection was made.Cet article décrit une étude expérimentale archéo-métallurgique sur l'acier creuset, menée en tant que projet maîtrise pour l’obtention du grade de master en conservation et restauration. Après avoir évalué les résultats des techniques différentes de fabrication, la technique de l’acier au creuset géorgien a montré des résultats similaires aux preuves archéologiques de Merv, au Turkménistan. Une réflexion historique a été menée à ce sujet.

Characterization Report on Sand, Slag, and Crucible Residues and on Fluoride Residues

International Nuclear Information System (INIS)

Murray, A.M.

1999-01-01

This paper reports on the chemical characterization of the sand, slag, and crucible (SS and C) residues and the fluoride residues that may be shipped from the Rocky Flats Environmental Technology Site (RFETS) to Savannah River Site (SRS)

Induction melting for volume reduction of metallic TRU wastes

International Nuclear Information System (INIS)

Westsik, J.H. Jr.; Montgomery, D.R.; Katayama, Y.B.; Ross, W.A.

1986-01-01

Volume reduction of metallic transuranic wastes offers economic and safety incentives for treatment of wastes generated at a hypothetical commercial fuel reprocessing facility. Induction melting has been identified as the preferred process for volume reduction of spent fuel hulls, fuel assembly hardware, and failed equipment from a reprocessing plant. Bench-scale melting of Zircaloy and stainless steel mixtures has been successfully conducted in a graphite crucible inside a large vacuum chamber. A low-melting-temperature alloy forms that has demonstrated excellent leach resistance. The alloy can be used to encapsulate other metallic wastes that cannot be melted using the existing equipment design

Fabrication of aluminum nitride crucibles for molten salt and plutonium compatibility studies

International Nuclear Information System (INIS)

Phillips, J.A.

1991-01-01

The overall objective of this research was to fabricate a calcium oxide sinter-aided aluminum nitride crucible and determine the compatibility of this crucible with molten chloride salts and plutonium metal in the DOR process. Calcium oxide sinter-aided aluminum nitride was preferred over yttrium oxide sinter-aided aluminum nitride because of (1) the presence of calcium chloride, calcium oxide, and calcium metal in the molten salts utilized in the DOR process, and (2) the higher volatility of the secondary phases formed compared with phases resulting from the addition of yttrium oxide during the aluminum nitride sintering process. The calcium oxide system may yield a higher purity crystal structure with fewer secondary phases present than in the yttrium oxide system. The secondary phases that are present in the grain boundaries may be unreactive with the calcium chloride salt due to the presence of calcium in the secondary phases

Characterisation in Ward’s opera The Crucible: melodic interpretation of Salem’s witches and their accusers via historical accounts and Miller’s play

OpenAIRE

Cornwell McKean, Julia Margaret

2017-01-01

ABSTRACT Characterisation in Ward’s opera The Crucible: Melodic interpretation of Salem’s witches and their accusers via historical accounts and Miller’s play This thesis is a consideration of the transition of the characters of Robert Ward’s opera The Crucible from history through to Arthur Miller’s play of the same name, and finally to the linear elements of the opera: the libretto and the vocal melodies. Arthur Miller’s The Crucible (1953) is widely known as a play that explor...

Treatment of NPP wastes using vitrification

International Nuclear Information System (INIS)

Sobolev, I.A.; Lifanov, F.A.; Stefanovsky, S.V.; Kobelev, A.P.; Savkin, A.E.; Kornev, V.I.

1998-01-01

Glass-based materials to immobilize various liquid and solid radioactive wastes generated at nuclear power plants (NPP) were designed. Glassy waste forms can be produced using electric melting including a cold crucible melting. Leach rate of cesium was found to be 10 -5 -10 -6 g/(cm 2 day) (IAEA technique). Volume reduction factor after vitrification reached 4-5. Various technologies for NPP waste vitrification were developed. Direct vitrification means feeding of source waste into the melter with formation of glassy waste form to be disposed. Joule heated ceramic melter, and cold crucible were tested. Process variables at treatment of Kursk, Chernobyl (RBMK), Kalinin, Novovoronezh (VVER) NPP wastes were determined. The most promising melter was found to be the cold crucible. Pilot plant based on the cold crucibles has been designed and constructed. Solid burnable NPP wastes are incinerated and slags are incorporated in glass. (author)

Crystal growth of YBa2Cu3O(7-x) and reaction of gold crucible with Ba-Cu-rich flux

Science.gov (United States)

Tao, Y. K.; Chen, H. C.; Martini, L.; Bechtold, J.; Huang, Z. J.; Hor, P. H.

1991-01-01

YBa2Cu3O(7-x) crystals are grown in a gold crucible by a self-flux method. The flux moves along the gold surface due to surface wetting and leaves Y123 crystals behind. The obtained crystals are clean and have a size up to two millimeters and a Tc is greater than 90 K. In an effort to recycle the used crucibles, it is found that the used gold is contaminated by copper. A CuO thin film is easily formed on the surface of the crucible that is made of the used gold. This film provides good surface wetting and a buffer layer, which reduces the reaction between gold and the Y-Ba-Cu-oxide melt.

Induction melting for volume reduction of metallic TRU wastes

International Nuclear Information System (INIS)

Westsik, J.H. Jr.; Montgomery, D.R.; Katayama, Y.B.; Ross, W.A.

1986-02-01

Volume reduction of metallic transuranic wastes offers economic and safety incentives for treatment of wastes generated at a hypothetical commercial fuel reprocessing facility. Induction melting has been identified as the preferred process for volume reduction of spent fuel hulls, fuel assembly hardware, and failed equipment from a reprocessing plant. Bench-scale melting of Zircaloy and stainless steel mixtures has been successfully conducted in a graphite crucible inside a large vacuum chamber. A low-melting-temperature alloy forms that has demonstrated excellent leach resistance. The alloy can be used to encapsulate other metallic wastes that cannot be melted using the existing equipment design. 18 refs., 4 figs., 3 tabs

Optimization of induction of mild therapeutic hypothermia with cold saline infusion: A laboratory experiment

Directory of Open Access Journals (Sweden)

Jure Fluher

2015-11-01

Full Text Available Cold fluid infusions can be used to induce mild therapeutic hypothermia after cardiac arrest. Fluid temperature higher than 4°C can increase the volume of fluid needed, prolong the induction phase of hypothermia and thus contribute to complications. We performed a laboratory experiment with two objectives. The first objective was to analyze the effect of wrapping fluid bags in ice packs on the increase of fluid temperature with time in bags exposed to ambient conditions. The second objective was to quantify the effect of insulating venous tubing and adjusting flow rate on fluid temperature increase from bag to the level of an intravenous cannula during a simulated infusion. The temperature of fluid in bags wrapped in ice packs was significantly lower compared to controls at all time points during the 120 minutes observation. The temperature increase from the bag to the level of intravenous cannula was significantly lower for insulated tubing at all infusion rates (median temperature differences between bag and intravenous cannula were: 8.9, 4.8, 4.0, and 3.1°C, for non-insulated and 5.9, 3.05, 1.1, and 0.3°C, for insulated tubing, at infusion rates 10, 30, 60, and 100 mL/minute, respectively. The results from this study could potentially be used to decrease the volume of fluid infused when inducing mild hypothermia with an infusion of cold fluids.

Fabricating tungsten crucibles by drawing and extrusion spinning

International Nuclear Information System (INIS)

Edstrom, C.M.

1981-01-01

The fabrication of seamless tungsten crucibles 127-mm ID x 265-mm high x 6.25-mm wall thickness (5 in. x 10 1/2 in. x 1/4 in.) involved three drawing operations and extrusion spinning. The success of the drawing operations came from a combination of low draw reduction percentage, generous draw radii, large punch-to-die clearance, and attention to drawing temperature. The extrusion spinning success related to good drawn-cup-to-spinning-mandrel fit prior to making the extrusion passes, removal of stress risers in the part prior to spinning, and special attention to part and mandrel temperature

Forced and thermocapillary convection in silicon Czochralski crystal growth in semispherical crucible

International Nuclear Information System (INIS)

Mokhtari, F; Bouabdallah, A; Zizi, M; Hanchi, S; Alemany, A

2010-01-01

In order to understand the influence of a semispherical crucible geometry combined with different convection modes as a thermocapillary convection, natural convection and forced convection, induced by crystal rotation, on melt flow pattern in silicon Czochralski crystal growth process, a set of numerical simulations are conducted using Fluent Software. We solve the system of equations of heat and momentum transfer in classical geometry as cylindrical and modified crystal growth process geometry as cylindro-spherical. In addition, we adopt hypothesis adapted to boundary conditions near the interface and calculations are executed to determine temperature, pressure and velocity fields versus Grashof and Reynolds numbers. The analysis of the obtained results led to conclude that there is advantage to modify geometry in comparison with the traditional one. The absence of the stagnation regions of fluid in the hemispherical crucible corner and the possibility to control the melt flow using the crystal rotation enhances the quality of the process comparatively to the cylindrical one. The pressure field is strongly related to the swirl velocity.

Forced and thermocapillary convection in silicon Czochralski crystal growth in semispherical crucible

Energy Technology Data Exchange (ETDEWEB)

Mokhtari, F [Physics Department, Faculty of Science, University of Mouloud Mammeri, Tizi Ouzou (Algeria); Bouabdallah, A; Zizi, M [LTSE Laboratory, University of Science and Technology USTHB. BP 32 Elalia, Babezzouar, Algiers (Algeria); Hanchi, S [UER Mecanique/ E.M.P B.P 17, Bordj El Bahri, Algiers (Algeria); Alemany, A, E-mail: abouab2002@yahoo.f [Laboratoire EPM, CNRS, Grenoble (France)

2010-03-01

In order to understand the influence of a semispherical crucible geometry combined with different convection modes as a thermocapillary convection, natural convection and forced convection, induced by crystal rotation, on melt flow pattern in silicon Czochralski crystal growth process, a set of numerical simulations are conducted using Fluent Software. We solve the system of equations of heat and momentum transfer in classical geometry as cylindrical and modified crystal growth process geometry as cylindro-spherical. In addition, we adopt hypothesis adapted to boundary conditions near the interface and calculations are executed to determine temperature, pressure and velocity fields versus Grashof and Reynolds numbers. The analysis of the obtained results led to conclude that there is advantage to modify geometry in comparison with the traditional one. The absence of the stagnation regions of fluid in the hemispherical crucible corner and the possibility to control the melt flow using the crystal rotation enhances the quality of the process comparatively to the cylindrical one. The pressure field is strongly related to the swirl velocity.

Alloy Development, Processing and Characterization of Devitrified Titanium Base Microcrystalline Alloys.

Science.gov (United States)

1986-01-01

1.5m wide by injecting the molten alloy onto a rotating copper ’. disk through the orifice at the bottom of the copper crucible under inert gas...icrocrystalline forms [10, 271. 7his technique adopts the combination of a water-cooled cold copper crucible with an arc heating scheme that uses non-consumable...are malted in the cold copper crucible and spun in an inert gas atmosphere. he ribbon produced has a uniform thickness of 20 to SOgm. 5’ -7 -. -F -i

The effects of vacuum induction melting and electron beam melting techniques on the purity of NiTi shape memory alloys

Energy Technology Data Exchange (ETDEWEB)

Otubo, J. [Instituto Tecnologico de Aeronautica (ITA), 12228-900 S.J. Campos, SP (Brazil) and DEMA-FEM-UNICAMP, 13083-000 Campinas, SP (Brazil)]. E-mail: jotubo@ita.br; Rigo, O.D. [DEMA-FEM-UNICAMP, 13083-000 Campinas, SP (Brazil); Neto, C. Moura [Instituto Tecnologico de Aeronautica (ITA), 12228-900 S.J. Campos, SP (Brazil); Mei, P.R. [DEMA-FEM-UNICAMP, 13083-000 Campinas, SP (Brazil)

2006-11-25

The usual process to produce NiTi shape memory alloys is by vacuum induction melting (VIM) using graphite crucible that contaminates the bath with carbon. The contamination by oxygen comes from residual oxygen inside the melting chamber. A new alternative process to produce NiTi alloys is by electron beam melting (EBM) using water-cooled copper crucible that eliminates the carbon contamination and the oxygen contamination would be minimized due to operation in high vacuum. This work compares the two processes and shows that the carbon contamination is four to ten times lower for EBM compared to VIM products and that the final oxygen content is much more dependent on the starting raw materials. The purity of the final product should be very important mainly in terms of biomedical applications and the contaminations by carbon and oxygen affect the direct and reverse martensitic transformation temperatures.

Wootz Crucible Steel: A Newly Discovered Production Site in South India

OpenAIRE

Sharad Srinivasan

1994-01-01

During the course of field investigations of copper mining and smelting in South India, the author of this paper came across a previously unrecorded archaeometallurgical site in Mel-siruvalur, South Arcot district, Tamil Nadu, which investigations have confinned was a production centre for wootz crucible steel in the Deccan. The find of this production centre supports the idea that wootz steel production was relatiYely widespread in South India, and extends the known horizons of this technolo...

Transient flows occurring during the accelerated crucible rotation technique

International Nuclear Information System (INIS)

Horowitz, Atara; Horowitz, Yigal

1992-11-01

The transient flows occurring after a change in the angular velocity of the cylindrical container are described. The dependence of the transient (known as spin-up or spin-down time) on experimental parameters as kinematic viscosity, cylinder dimensions and the cylinder's initial and final angular velocities are elucidates by a review of the literature. It is emphasized that with large Rossby numbers the spin-up time is longer and the amount of fluid mixing is greater than small and moderate Rossby numbers. It is also elucidated that most crystal growth crucibles cannot be considered as infinitely-long cylinders for the evaluation of the fluid dynamics (authors)

Modelling of the draining of a molten glass heated by induction

International Nuclear Information System (INIS)

Lima-Da-Silva, Marcio

2014-01-01

This thesis is part of the development of a new technology of oxides melting in a furnace heated by induction. The technology studied involves strong interactions between electromagnetic, thermal and hydrodynamic phenomena in a flow with physical properties strongly dependents of the temperature. The aim of the thesis is the modelling of the process by coupling closely the Joule heating, the mechanical stirring and the draining of the furnace. The modeling of the time evolution of the interface between glass and air during the emptying of the cold crucible was performed. Regarding the methodology, we chose to combine two scientific codes: Flux for the electromagnetic calculation and Fluent for thermal-hydraulics. The evolution of the free surface was treated by the multiphasic method 'Volume-Of-Fluid - VOF' and the mechanical stirring by the 'Moving Reference Frame' and the 'Sliding Mesh'. First of all, we considered the draining of a tank filled with a silicon oil of high-viscosity without mechanical stirring. This initial model took into account studies of hydraulic similarity between the silicon oil and the glass. Then we superimposed the forced flow creates by the mechanical stirrer, the thermal and the electromagnetic phenomena in order to model the flow of the molten glass. The final model can provide various parameters, including the time needed to drain the furnace, the heat transfer flux and the time evolution of the mass flow rate and of the temperature inside de furnace. (author) [fr

Utilizing Rice Husk Briquettes in Firing Crucible Furnace for Low Temperature Melting Metals in Nigeria

Directory of Open Access Journals (Sweden)

N. A. Musa

2012-08-01

Full Text Available The search for alternative fuels for firing crucible furnace for low temperature melting metals has become mandatory, as a result of the pollution problem associated with the use of fossil fuels, the expense of electricity and also deforestation as a result of the use of charcoal. An agricultural waste, rice husk, in briquette form was used as an alternative fuel to fire crucible furnace to melt lead, zinc and aluminium. Results showed that lead and zinc melted and reached their pouring temperatures of 3840C and 5300C in 70 minutes and 75 minutes respectively. Aluminium was raised to a maximum temperature of 5200C in 75 and 100 minutes.The average concentration of the pollutants (CO, SO2and NOX were found to be below the tolerance limit and that of TSP (Total Suspended Particulates was found to be within the tolerance limit stipulated by Federal Environmental Protection Agency (FEPA in Nigeria.

Vitrification of high level nuclear waste inside ambient temperature disposal containers using inductive heating: The SMILE system

International Nuclear Information System (INIS)

Powell, J.; Reich, M.; Barletta, R.

1996-01-01

A new approach, termed SMILE (Small Module Inductively Loaded Energy), for the vitrification of high level nuclear wastes (HLW) is described. Present vitrification systems liquefy the HLW solids and associated frit material in large high temperature melters. The molten mix is then poured into small (∼1 m 3 ) disposal canisters, where it solidifies and cools. SMILE eliminates the separate, large high temperature melter. Instead, the BLW solids and frit melt inside the final disposal containers, using inductive heating. The contents then solidify and cool in place. The SMILE modules and the inductive heating process are designed so that the outer stainless can of the module remains at near ambient temperature during the process cycle. Module dimensions are similar to those of present disposal containers. The can is thermally insulated from the high temperature inner container by a thin layer of refractory alumina firebricks. The inner container is a graphite crucible lined with a dense alumina refractory that holds the HLW and fiit materials. After the SMILE module is loaded with a slurry of HLW and frit solids, an external multi-turn coil is energized with 30-cycle AC current. The enclosing external coil is the primary of a power transformer, with the graphite crucible acting as a single turn ''secondary.'' The induced current in the ''secondary'' heats the graphite, which in turn heats the HLW and frit materials. The first stage of the heating process is carried out at an intermediate temperature to drive off remnant liquid water and water of hydration, which takes about 1 day. The small fill/vent tube to the module is then sealed off and the interior temperature raised to the vitrification range, i.e., ∼1200C. Liquefaction is complete after approximately 1 day. The inductive heating then ceases and the module slowly loses heat to the environment, allowing the molten material to solidify and cool down to ambient temperature

Energy Dissipation Rate in an Agitated Crucible Containing Molten Metal

Science.gov (United States)

Li, Tao; Shimasaki, Shin-ichi; Narita, Shunsuke; Taniguchi, Shoji

2017-10-01

The energy dissipation rate (EDR) is an important parameter for characterizing the behavior of inclusion coagulation in agitated molten metal. To clarify the inclusion coagulation mechanism, we review previous water model studies by particularly focusing on the relation between the impeller torque and the EDR of the fluid, which indicates the ratio of energy dissipated in the viscous medium to the energy inputted by the rotating impeller. In the present study, simulations coupled with experiments were performed to determine the relation between the torque and the effective EDR for water and liquid Al in crucibles with and without baffles.

Numerical study of crucial parameters in tilt casting for titanium aluminides

Directory of Open Access Journals (Sweden)

Hong Wang

2011-08-01

Full Text Available Numerical modeling of the tilt casting process for TiAl alloys was investigated to achieve a tranquil mould filling and TiAl castings free of defects. Titanium alloys are very reactive in molten state, so they are widely melted in cold crucible, e.g. the Induction Skull Melting (ISM furnace. Then the crucible holding the molten metal together with the mould is rotated to transfer the metal into the mould — ISM+ tilt casting. This paper emphasizes the effect of crucial parameters on mould filling and solidification of the castings during tilt casting. All crucial parameters, such as rotation rate, rotation profile, venting, initial mould temperature, casting orientation, feeder design, change of radius in 'T' junction and mould insulation have been discussed using numerical modeling data. Simulations were performed using a 3D CFD code PHYSICA implemented with front tracking, heat transfer algorithms and a turbulence model (which accounts for an advancing solid front.

Melt-processing method for radioactive solid wastes

International Nuclear Information System (INIS)

Kobayashi, Hiroaki

1998-01-01

Radioactive solid wastes are charged into a water-cooled type cold crucible induction melting furnace disposed in high frequency coils, and high frequency currents are supplied to high frequency coils which surround the melting furnace to melt the solid wastes by induction-heating. In this case, heat plasmas are jetted from above the solid wastes to the solid wastes to conduct initial heating to melt a portion of the solid wastes. Then, high frequency currents are supplied to the high frequency coils to conduct induction heating. According to this method, even when waste components of various kinds of materials are mixed, a portion of the solid wastes in the induction melting furnace can be melted by the initial heating by jetting heat plasmas irrespective of the kinds and the electroconductivity of the materials of the solid wastes. With such procedures, entire solid wastes in the furnace can be formed into a molten state uniformly and rapidly. (T.M.)

Heat and mass transfer during the inductive skull melting process of glasses and oxides; Waerme- und Stofftransport beim induktiven Skull-Schmelzen von Glaesern und Oxiden

Energy Technology Data Exchange (ETDEWEB)

Nacke, Bernard; Niemann, Benjamin [Leibniz Univ. Hannover (Germany). Inst. fuer Elektroprozesstechnik; Schlesselmann, Dirk [Auer Lighting GmbH, Bad Gandersheim (Germany)

2013-03-15

The skull melting technology is a melting process for innovative materials in the range of glasses. A hitherto unknown problem under glass melting by means of this technology is the fact that the processes in the interior of the molten mass are still unknown. Under this aspect, the authors of the contribution under consideration present an overview of the inductive melting process for glasses in an inductor crucible developed at the Institute for Electrotechnology (Hanover, Federal Republic of Germany). A newly developed numerical model is presented in order to simulate the heat and mass transfer in a molten glass. This simulation enables a future optimization of the design of the inductor crucible and the melting process. The transient three-dimensional melting flow during the melting of glasses and oxides by means of the skull meeting process also can be simulated by the newly developed numerical model.

Water boiling on the corium melt surface under VVER severe accident conditions

International Nuclear Information System (INIS)

Bechta, S.V.; Vitol, S.A.; Krushinov, E.V.; Granovsky, V.S.; Sulatsky, A.A.; Khabensky, V.B.; Lopukh, D.B.; Petrov, Y.B.; Pechenkov, A.Y.

2000-01-01

Experimental results are presented on the interaction of corium melt with water supplied on its surface. The tests were conducted in the 'Rasplav-2' experimental facility. Corium melt was generated by induction melting in the cold crucible. The following data were obtained: heat transfer at boiling water-melt surface interaction, gas and aerosol release, post-interaction solidified corium structure. The corium melt charge had the following composition, mass%: 60% UO 2+x -16% ZrO 2 -15% Fe 2 O 3 -6% Cr 2 O 3 -3% Ni 2 O 3 . The melt surface temperature ranged within 1920-1970 K. (orig.)

Water boiling on the corium melt surface under VVER severe accident conditions

International Nuclear Information System (INIS)

Bechta, S.V.; Vitol, S.A.; Krushinov, E.V.

1999-01-01

Experimental results are presented on the interaction between corium melt and water supplied onto its surface. The tests were conducted on the Rasplav-2' experimental facility. Induction melting in a cold crucible was used to produce the melt. The following data have been obtained: heat transfer at water boiling on the melt surface, aerosol release, structure of the post-interaction solidified corium. The corium melt had the following composition, mass %: 60%UO 2 - 16%ZrO 2 - 15%Fe 2 O 3 - 6%Cr 2 O 3 -3%Ni 2 O 3 . The melt surface temperature was 1650-1700degC. (author)

A feasibility study on the vitrification of low-level radioactive waste

Energy Technology Data Exchange (ETDEWEB)

Song, Myung Jae; Park, Jong Kil; Ahn, Hee Jin [Korea Electric Power Corp. (KEPCO), Taejon (Korea, Republic of). Research Center; Cho, Jeong Mi; Choe, Young Son; Cho, Myeong Ryul [Hankuk Fiber Group (Korea, Republic of)

1995-12-31

A Study was carried out to investigate the feasibility of vitrification for low-and medium-level radioactive waste(LMLW). In order to understand maximum yearly generation volume and composition for each waste streams waste generation trends, which have been produced from nuclear power plants(PWR) in korea, were examined and then technical and economical assessment were performed based on the volume and composition. To select the most promising melters, technical characteristics were analyzed for several melters such as cold crucible melter heated by direct induction(CCM), cold crucible melter heated by vertical electrodes(CCVE), molten metal melter(MM), and plasma melter(PM) which were most likely to be applied to LMLW treatment. Economical assessment was carried out for several treatment strategies with selected melters and resulted in that it was desirable that non-combustibles and spent filter were vitrified with PM, and the others with CCM. For the demonstration of vitrification possibility for protective clothing, vinyl seats, spent resin, and evaporator bottoms, the surrogated wastes were paralyzed or dried at optimal conditions and than specimens contained various percentages of pyrolysis ash were prepared with lab. and pilot scale melters. Compressive strength for these specimens was measured to determine the maximum ash content in glass waste forms. (author). 27 refs., 88 figs.

A feasibility study on the vitrification of low-level radioactive waste

Energy Technology Data Exchange (ETDEWEB)

Song, Myung Jae; Park, Jong Kil; Ahn, Hee Jin [Korea Electric Power Corp. (KEPCO), Taejon (Korea, Republic of). Research Center; Cho, Jeong Mi; Choe, Young Son; Cho, Myeong Ryul [Hankuk Fiber Group (Korea, Republic of)

1996-12-31

A Study was carried out to investigate the feasibility of vitrification for low-and medium-level radioactive waste(LMLW). In order to understand maximum yearly generation volume and composition for each waste streams waste generation trends, which have been produced from nuclear power plants(PWR) in korea, were examined and then technical and economical assessment were performed based on the volume and composition. To select the most promising melters, technical characteristics were analyzed for several melters such as cold crucible melter heated by direct induction(CCM), cold crucible melter heated by vertical electrodes(CCVE), molten metal melter(MM), and plasma melter(PM) which were most likely to be applied to LMLW treatment. Economical assessment was carried out for several treatment strategies with selected melters and resulted in that it was desirable that non-combustibles and spent filter were vitrified with PM, and the others with CCM. For the demonstration of vitrification possibility for protective clothing, vinyl seats, spent resin, and evaporator bottoms, the surrogated wastes were paralyzed or dried at optimal conditions and than specimens contained various percentages of pyrolysis ash were prepared with lab. and pilot scale melters. Compressive strength for these specimens was measured to determine the maximum ash content in glass waste forms. (author). 27 refs., 88 figs.

Study on plasma melting treatment of crucibles, ceramic filter elements, asbestos, and fly ash

International Nuclear Information System (INIS)

Hoshi, Akiko; Nakasio, Nobuyuki; Nakajima, Mikio

2004-01-01

The Japan Atomic Energy Research Institute (JAERI) decided to adopt an advanced volume reduction program for low-level radioactive wastes. In this program, inorganic wastes are converted to stable glassy products suitable for disposal by a plasma melting system in the Waste Volume Reduction Facilities (WVRF). High melting point wastes such as refractories are excluded from the plasma melting treatment in the WVRF, and wastes difficult to handle such as asbestos are also excluded. However, it is describable to apply the plasma melting treatment to these wastes for stabilization and volume reduction from the viewpoint of disposal. In this paper, plasma melting test of crucibles, ceramic filter elements, asbestos, and simulated fly ashes were carried out as a part of technical support for WVRF. The plasma melting treatment was applicable for crucibles and asbestos because homogeneous and glassy products were obtained by controlling of waste and loading condition. It was found that SiC in ceramic filter elements was volatile with a plasma torch with inert gas, and adding reducer was ineffective against stabilizing volatile metals such as Zn, Pb in a solidified product in the melting test of simulated fly ash. (author)

Cladding hull decontamination and densification process. Part 2. Densification by inductoslag melting

International Nuclear Information System (INIS)

Nelson, R.G.; Montgomery, D.R.

1980-04-01

The Inductoslag melting process was developed to densify Zircaloy-4 cladding hulls. It is a cold crucible process that uses induction heating, a segmented water-cooled copper crucible, and a calcium fluoride flux. Metal and flux are fed into the furnace through the crucible, located at the top of the furnace, and the finished ingot is withdrawn from the bottom of the furnace. Melting rates of 40 to 50 kg/h are achieved, using 100 to 110 kW at an average energy use of 2.5 kWh/kg. The quality of ingots produced from factory supplied cladding tubing is sufficient to satisfy nuclear grade standards. An ingot of Zircaloy-4, made from melted cladding tubing that had been autoclaved to near reactor exposure and then descaled by the hydrogen fluoride decontamination process prior to Inductoslag melting, did not meet nuclear grade standards because the hydrogen, nitrogen, and hardness levels were too high. Melting development work is described that could possibly be used to test the capability of the Inductoslag process to satisfactorily melt a variety and mix of materials from LWR reprocessing, decontamination, and storage options. Results of experiments are also presented that could be used to improve remote operation of the melting process

A Feasibility Study on UO2/ZrO2 Mixture Melting using Induction Skull Melting Method

International Nuclear Information System (INIS)

Hong, S. W.; Kim, J. H.; Kim, H. D.

1998-01-01

Using ISM(Induction Skull Melting) method, which is usually used for the crystallization of refractory materials, a feasibility study on melting of the UO 2 /ZrO 2 mixture(w/o 8:2) is carried out. Frequency, one of main design parameters for ISM, is determined from electrical resistance of UO 2 /ZrO 2 mixture. Heat loss from the crucible for UO 2 /ZrO 2 20kg melting is predicted by comparison with the existing experimental data for UO , ZrO 2 , and ThO 2 . The analysis shows that melting and superheating of the UO 2 /ZrO 2 mixture using induction skull melting method is possible. To attain the superheat of 300K for 20 kg of UO 2 /ZrO 2 , 100kHz, 100 kW power input for induction coil, and 570L/min coolant flow rate are found to be required. The results of this feasibility study will be adopted for designing UO 2 /ZrO 2 furnace using actual corium material at KAERI

Melting method for miscellaneous radioactive solid waste and melting furnace

International Nuclear Information System (INIS)

Osaki, Toru; Furukawa, Hirofumi; Uda, Nobuyoshi; Katsurai, Kiyomichi

1998-01-01

A vessel containing miscellaneous solid wastes is inserted in a crucible having a releasable material on the inner surface, they are induction-heated from the outside of the crucible by way of low temperature heating coils to melt low melting point materials in the miscellaneous wastes within a temperature range at which the vessel does not melt. Then, they are induction-heated by way of high temperature heating coils to melt the vessel and not yet melted materials, those molten materials are cooled, solidified molten material and the releasable material are taken out, and then the crucible is used again. Then, the crucible can be used again, so that it can be applied to a large scaled melting furnace which treats wastes by a unit of drum. In addition, since the cleaning of the used crucible and the application of the releasable material can be conducted without interrupting the operation of the melting furnace, the operation cycle of the melting furnace can be shortened. (N.H.)

The induction furnace as a melting facility in steel production. Pt. 1. Features of induction furnaces used in steel production; Der Induktionsofen als Schmelzaggregat fuer die Stahlerzeugung. T. 1. Merkmale von Induktionsoefen in der Stahlerzeugung

Energy Technology Data Exchange (ETDEWEB)

Chaabet, Mohamed; Doetsch, Erwin [ABP Induction Systems GmbH, Dortmund (Germany)

2011-12-15

Global steel output has now been growing extremely rapidly for a prolonged time; in the past ten years alone, annual production has risen from 851 million t/a (in 2001) to 1417 million t/a (2010), as a result, primarily, of growth in China. Electric steel production using the electric arc furnace as the classical melting facility is around 45 % world-wide, with a rising trend (but excluding the special case of China, where oxygen-route steel holds a 90 % share of production). Following the development of induction technology and inverter outputs of over 40 MW for crucible furnaces with capacities of above 65 t, the induction furnace is now available as an alternative electrical melting installation for use in smaller mini steel mills. The benefits of this technology can be found in high feed-material efficiencies and low environmental and workplace burdens, in addition to the absence of electrode costs and the only modest demands made on the power-supply grid. These features of the induction furnace and their special significance for steel production are examined in Part 1 of this article. The second part of the article then focuses on examples of the use of induction furnaces in the steelmaking plant. (orig.)

Characterization of a High-Level Waste Cold Cap in a Laboratory-Scale Melter

Energy Technology Data Exchange (ETDEWEB)

Dixona, Derek R; Schweiger, Michael J; Hrma, Pavel [Pacific Northwest National Laboratory, Richland (United States)

2013-05-15

The feed, slurry or calcine, is charged to the melter from above. The conversion of the melter feed to molten glass occurs within the cold cap, a several centimeters thin layer of the reacting material blanketing the surface of the melt. Between the cold-cap top, which is covered by boiling slurry, and its bottom, where bubbles separate it from molten glass, the temperature changes by ∼900 .deg. C. The heat is delivered to the cold cap from the melt that is stirred mainly by bubbling. The feed contains oxides, hydroxides, acids, inorganic salts and organic materials. On heating, these components react, releasing copious amounts of gases, while molten salts decompose, glass-forming melt is generated, and crystalline phases precipitate and dissolve in the melt. Most of these processes have been studied in detail and became sufficiently understood for a mathematical model to represent the heat and mass transfer within the cold cap. This allows US to relate the rate of melting to the feed properties. While the melting reactions can be studied, and feed properties, such as heat conductivity and density, measured in the laboratory, the actual cold-cap dynamics, as it evolves in the waste glass melter, is not accessible to direct investigation. Therefore, to bridge the gap between the laboratory crucible and the waste glass melter, we explored the cold cap formation in a laboratory-scale melter (LSM) and studied the structure of quenched cold caps. The LSM is a suitable tool for investigating the cold cap. The cold cap that formed in the LSM experiments exhibited macroscopic features observed in scaled melters, as well as microscopic features accessible through laboratory studies and mathematical modeling. The cold cap consists of two main layers. The top layer contains solid particles dissolving in the glass-forming melt and open shafts through which gases are escaping. The bottom layer contains bubbly melt or foam where bubbles coalesce into larger cavities that move

Water boiling on the corium melt surface under VVER severe accident conditions

Energy Technology Data Exchange (ETDEWEB)

Bechta, S.V.; Vitol, S.A.; Krushinov, E.V.; Granovsky, V.S.; Sulatsky, A.A.; Khabensky, V.B. [Sci. Res. Technol. Inst., Leningrad (Russian Federation); Lopukh, D.B.; Petrov, Y.B.; Pechenkov, A.Y. [St. Petersburg Electrotechnical University (SPbEU), Prof. Popov st 5/3, St. Petersburg (Russian Federation)

2000-01-01

Experimental results are presented on the interaction of corium melt with water supplied on its surface. The tests were conducted in the 'Rasplav-2' experimental facility. Corium melt was generated by induction melting in the cold crucible. The following data were obtained: heat transfer at boiling water-melt surface interaction, gas and aerosol release, post-interaction solidified corium structure. The corium melt charge had the following composition, mass%: 60% UO{sub 2+x}-16% ZrO{sub 2}-15% Fe{sub 2}O{sub 3}-6% Cr{sub 2}O{sub 3}-3% Ni{sub 2}O{sub 3}. The melt surface temperature ranged within 1920-1970 K. (orig.)

Water boiling on the corium melt surface under VVER severe accident conditions

Energy Technology Data Exchange (ETDEWEB)

Bechta, S.V.; Vitol, S.A.; Krushinov, E.V. [Research Institute of Technology, Sosnovy Bor (NITI) (RU)] [and others

1999-07-01

Experimental results are presented on the interaction between corium melt and water supplied onto its surface. The tests were conducted on the Rasplav-2' experimental facility. Induction melting in a cold crucible was used to produce the melt. The following data have been obtained: heat transfer at water boiling on the melt surface, aerosol release, structure of the post-interaction solidified corium. The corium melt had the following composition, mass %: 60%UO{sub 2}- 16%ZrO{sub 2}- 15%Fe{sub 2}O{sub 3} - 6%Cr{sub 2}O{sub 3}-3%Ni{sub 2}O{sub 3}. The melt surface temperature was 1650-1700degC. (author)

New Treatment Options for Osteosarcoma - Inactivation of Osteosarcoma Cells by Cold Atmospheric Plasma.

Science.gov (United States)

Gümbel, Denis; Gelbrich, Nadine; Weiss, Martin; Napp, Matthias; Daeschlein, Georg; Sckell, Axel; Ender, Stephan A; Kramer, Axel; Burchardt, Martin; Ekkernkamp, Axel; Stope, Matthias B

2016-11-01

Cold atmospheric plasma has been shown to inhibit tumor cell growth and induce tumor cell death. The aim of the study was to investigate the effects of cold atmospheric plasma treatment on proliferation of human osteosarcoma cells and to characterize the underlying cellular mechanisms. Human osteosarcoma cells (U2-OS and MNNG/HOS) were treated with cold atmospheric plasma and seeded in culture plates. Cell proliferation, p53 and phospho-p53 protein expression and nuclear morphology were assessed. The treated human osteosarcoma cell lines exhibited attenuated proliferation rates by up to 66%. The cells revealed an induction of p53, as well as phospho-p53 expression, by 2.3-fold and 4.5-fold, respectively, compared to controls. 4',6-diamidino-2-phenylindole staining demonstrated apoptotic nuclear condensation following cold atmospheric plasma treatment. Cold atmospheric plasma treatment significantly attenuated cell proliferation in a preclinical in vitro osteosarcoma model. The resulting increase in p53 expression and phospho-activation in combination with characteristic nuclear changes indicate this was through induction of apoptosis. Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

Ductile-phase toughening in V-V3Si in situ composites

International Nuclear Information System (INIS)

Henshall, G.; Strum, M.J.; Bewlay, B.P.; Sutliff, J.A.

1997-01-01

This article describes the room-temperature fracture behavior of ductile-phase-toughened V-V 3 Si in situ composites that were produced by arc melting (AM), cold-crucible induction melting (IM), and cold-crucible directional solidification (DS). Composites were produced containing a wide range of microstructures, interstitial impurity contents, and volume fractions of the ductile V-Si solid solution phase, denoted (V). The fracture toughness of these composites generally increases as the volume fraction of (V) increases, but is strongly influenced by the microstructure, the mechanical properties of the component phases, and the crystallographic orientation of the (V) phase with respect to the maximum principal stress direction. For eutectic composites that have a (V) volume fraction of about 50 pct, the fracture toughness increases with decreasing ''''effective'''' interstitial impurity concentration, [I] = [N] + 1.33 [O] + 9 [H]. As [I] decreases from 1,400 ppm (AM) to 400 ppm (IM), the fracture toughness of the eutectic composites increases from 10 to 20 MPa √m. Further, the fracture toughness of the DS eutectic composites is greater when the crack propagation direction is perpendicular, rather than parallel, to the composite growth direction. These results are discussed in light of conventional ductile-phase bridging theories, which alone cannot fully explain the fracture toughness of V-Si in situ composites

Pre-cold stress increases acid stress resistance and induces amino ...

African Journals Online (AJOL)

pre-adapted to cold stress revealed induction of amino acid homeostasis and energy ... substrate, thereby reducing yeast and mould ..... spontaneous mutation of llmg_1816 (gdpp) induced by .... species to UV-B-induced damage in bacteria. J.

A role for circadian evening elements in cold-regulated gene expression in Arabidopsis.

Science.gov (United States)

Mikkelsen, Michael D; Thomashow, Michael F

2009-10-01

The plant transcriptome is dramatically altered in response to low temperature. The cis-acting DNA regulatory elements and trans-acting factors that regulate the majority of cold-regulated genes are unknown. Previous bioinformatic analysis has indicated that the promoters of cold-induced genes are enriched in the Evening Element (EE), AAAATATCT, a DNA regulatory element that has a role in circadian-regulated gene expression. Here we tested the role of EE and EE-like (EEL) elements in cold-induced expression of two Arabidopsis genes, CONSTANS-like 1 (COL1; At5g54470) and a gene encoding a 27-kDa protein of unknown function that we designated COLD-REGULATED GENE 27 (COR27; At5g42900). Mutational analysis indicated that the EE/EEL elements were required for cold induction of COL1 and COR27, and that their action was amplified through coupling with ABA response element (ABRE)-like (ABREL) motifs. An artificial promoter consisting solely of four EE motifs interspersed with three ABREL motifs was sufficient to impart cold-induced gene expression. Both COL1 and COR27 were found to be regulated by the circadian clock at warm growth temperatures and cold-induction of COR27 was gated by the clock. These results suggest that cold- and clock-regulated gene expression are integrated through regulatory proteins that bind to EE and EEL elements supported by transcription factors acting at ABREL sequences. Bioinformatic analysis indicated that the coupling of EE and EEL motifs with ABREL motifs is highly enriched in cold-induced genes and thus may constitute a DNA regulatory element pair with a significant role in configuring the low-temperature transcriptome.

Leading research report for fiscal 1998 on the next-generation cold emission technology; 1998 nendo jisedai cold emission gijutsu no chosa kenkyu sendo kenkyu hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-03-01

The report covers the fruits of researches into technologies of cold emission control and cold emission application conducted in fiscal 1998. In the study relative to the current status of cold emission control technology, emitter materials that govern electron emitting characteristics are discussed, such as metallic materials, silicon, carbon systems, semiconductors, liquid metal, etc. In relation with the application of semiconductor process technology, the tunnel emitter is taken up that utilizes the semiconductor tunnel cathode. In relation with the cold emission process, an emitter high in aspect ratio is described, obtained by the inductive emitter deposition method in which organic metallic gas is decomposed by an electron beam. In the study of the cold emission control system and instrumentation, the merits and demerits of control by MOSFET (MOS field effect transistor) are discussed. In relation with the technology of cold emission application, FED (field effect display) development and problems, current status of sensor technology and problems, RF application technology, application to power systems, etc., are mentioned. (NEDO)

RNA-Seq-based analysis of the physiologic cold shock-induced changes in Moraxella catarrhalis gene expression.

Directory of Open Access Journals (Sweden)

Violeta Spaniol

Full Text Available BACKGROUND: Moraxella catarrhalis, a major nasopharyngeal pathogen of the human respiratory tract, is exposed to rapid downshifts of environmental temperature when humans breathe cold air. The prevalence of pharyngeal colonization and respiratory tract infections caused by M. catarrhalis is greatest in winter. We investigated how M. catarrhalis uses the physiologic exposure to cold air to regulate pivotal survival systems that may contribute to M. catarrhalis virulence. RESULTS: In this study we used the RNA-seq techniques to quantitatively catalogue the transcriptome of M. catarrhalis exposed to a 26 °C cold shock or to continuous growth at 37 °C. Validation of RNA-seq data using quantitative RT-PCR analysis demonstrated the RNA-seq results to be highly reliable. We observed that a 26 °C cold shock induces the expression of genes that in other bacteria have been related to virulence a strong induction was observed for genes involved in high affinity phosphate transport and iron acquisition, indicating that M. catarrhalis makes a better use of both phosphate and iron resources after exposure to cold shock. We detected the induction of genes involved in nitrogen metabolism, as well as several outer membrane proteins, including ompA, m35-like porin and multidrug efflux pump (acrAB indicating that M. catarrhalis remodels its membrane components in response to downshift of temperature. Furthermore, we demonstrate that a 26 °C cold shock enhances the induction of genes encoding the type IV pili that are essential for natural transformation, and increases the genetic competence of M. catarrhalis, which may facilitate the rapid spread and acquisition of novel virulence-associated genes. CONCLUSION: Cold shock at a physiologically relevant temperature of 26 °C induces in M. catarrhalis a complex of adaptive mechanisms that could convey novel pathogenic functions and may contribute to enhanced colonization and virulence.

Progress in atomizing high melting intermetallic titanium based alloys by means of a novel plasma melting induction guiding gas atomization facility (PIGA)

Energy Technology Data Exchange (ETDEWEB)

Gerling, R.; Schimansky, F.P.; Wagner, R. [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Inst. fuer Werkstofforschung

1994-12-31

For the production of intermetallic titanium based alloy powders a novel gas atomization facility has been put into operation: By means of a plasma torch the alloy is melted in a water cooled copper crucible in skull melting technique. To the tap hole of the crucible, a novel transfer system is mounted which forms a thin melt stream and guides it into the gas nozzle. This transfer system consists of a ceramic free induction heated water cooled copper funnel. Gas atomization of {gamma}-TiAl (melting temperature 1400 C) and Ti{sub 5}Si{sub 3} (2130 C) proved the possibility to produce ceramic free pre-alloyed powders with this novel facility. The TiAl powder particles are spherical; about 20 wt.% are smaller than 45 {mu}m. The oxygen and copper pick up during atomization do not exceed 250 and 35 {mu}g/g respectively. The Ti{sub 5}Si{sub 3} powder particles are almost spherical. Only about 10 wt.% are <45 {mu}m whereas the O{sub 2} and Cu contamination is also kept at a very low level (250 and 20 {mu}g/g respectively). (orig.)

Frit screening for Rocky Flats ash and sand, slag, and crucible vitrification

International Nuclear Information System (INIS)

Vienna, J.D.; Li, Hong; Darab, J.G.

1997-06-01

Pacific Northwest National Laboratory (PNNL) is developing vitrified waste forms for plutonium-bearing ash and plutonium-bearing sand, slag, and crucible (SS ampersand C) materials from Rocky Flats. Waste forms are to meet product criteria (e.g., safeguard termination limits, storage criteria, and target plutonium loading) and processing constraints (e.g., upper temperature limits, processing time, and equipment compatibility). The target waste form for ash is an agglomerated product, while that for SS ampersand C is a fully encapsulated product. Laboratory scoping studies were conducted on glass formulations from six different glass families: (1) antimony vanadium phosphate, (2) iron vanadium phosphate, (3) tin zinc phosphate, (4) soda-lime silicate, (5) alkali borosilicate, and (6) alkali borate. Glass families were selected due to viscosity behavior in the temperature range of interest (< 800C). Scoping study tests included gradient furnace tests to determine processing range and sintering temperature, thermogravimetric analysis to determine weight loss as a function of temperature, and crucible tests to determine frit compositions tolerance to variations in processing temperature, waste loading, and waste type. The primary screening criterion for the selection of frits for future studies was processing temperature below 400C to minimize the potential for foaming in ash caused by the release of gases (main source of gas is combustion of carbon species) and to minimize processing cycle times. Based on this criterion, glass formulations from the tin zinc phosphate and alkali borosilicate families were selected for future variability testing. Variability testing will include final product evaluation, glass system tolerance to waste loading and composition variation, and identification of parameters impacting time/temperature profiles. Variability testing results will give a final frit formulation for ash and SS ampersand C, and identify key processing parameters

Incineration ash conditioning processes

International Nuclear Information System (INIS)

Jouan, A.; Ouvrier, N.; Teulon, F.

1990-01-01

Incinerable wastes consist of the following standard composition corresponding to projected wastes from a future mixed oxide fuel fabrication plant with an annual throughput of 1700 kg (i.e. 5.7 m 3 ) of ashes produced by the incineration facility: . 50% polyvinyl chloride (glove box sleeves), . 5% polyethylene (bags), . 35% rubber (equal amounts of latex and neoprene), . 10% cellulose (equal amounts of cotton and cleansing tissues). The work focused mainly on compaction by high-temperature isostatic pressing, is described in some detail with the results obtained. An engineering study was also carried out to compare this technology with two other ash containment processes: direct-induction (cold crucible) melting and cement-resin matrix embedding. Induction melting is considerably less costly than isostatic pressing; the operating costs are about 1.5 times higher than for cement-resin embedding, but the volume reduction is nearly 3 times greater

Viscosity calculations of simulated ion-exchange resin waste glasses

International Nuclear Information System (INIS)

Kim, Cheon Woo; Park, Jong Kil; Lee, Kyung Ho; Lee, Myung Chan; Song, Myung Jae; BRUNELOT, Pierre

2000-01-01

An induction cold crucible melter (CCM) located in the NETEC-KEPCO has been used to vitrify simulated ion-exchange resin. During vitrification, the CCM operations were tightly constrained by glass viscosity as an important process parameter. Understanding the role of viscosity and quantifying viscosity is highly required in the determination of optimized feed formulations and in the selection of the processing temperature. Therefore, existing process models of glass viscosity based on a relationship between the glass composition, its structure polymerization, and the temperature were searched and adapted to our borosilicate glass systems. Calculated data using a viscosity model based on calculation of non-bridging oxygen (NBO) were in good agreement with the measured viscosity data of benchmark glasses

Amelioration of cold injury-induced cortical brain edema formation by selective endothelin ETB receptor antagonists in mice.

Science.gov (United States)

Michinaga, Shotaro; Nagase, Marina; Matsuyama, Emi; Yamanaka, Daisuke; Seno, Naoki; Fuka, Mayu; Yamamoto, Yui; Koyama, Yutaka

2014-01-01

Brain edema is a potentially fatal pathological condition that often occurs in stroke and head trauma. Following brain insults, endothelins (ETs) are increased and promote several pathophysiological responses. This study examined the effects of ETB antagonists on brain edema formation and disruption of the blood-brain barrier in a mouse cold injury model (Five- to six-week-old male ddY mice). Cold injury increased the water content of the injured cerebrum, and promoted extravasation of both Evans blue and endogenous albumin. In the injury area, expression of prepro-ET-1 mRNA and ET-1 peptide increased. Intracerebroventricular (ICV) administration of BQ788 (ETB antagonist), IRL-2500 (ETB antagonist), or FR139317 (ETA antagonist) prior to cold injury significantly attenuated the increase in brain water content. Bolus administration of BQ788, IRL-2500, or FR139317 also inhibited the cold injury-induced extravasation of Evans blue and albumin. Repeated administration of BQ788 and IRL-2500 beginning at 24 h after cold injury attenuated both the increase in brain water content and extravasation of markers. In contrast, FR139317 had no effect on edema formation when administrated after cold injury. Cold injury stimulated induction of glial fibrillary acidic protein-positive reactive astrocytes in the injured cerebrum. Induction of reactive astrocytes after cold injury was attenuated by ICV administration of BQ788 or IRL-2500. These results suggest that ETB receptor antagonists may be an effective approach to ameliorate brain edema formation following brain insults.

Cold urticaria patients exhibit normal skin levels of functional mast cells and histamine after tolerance induction

DEFF Research Database (Denmark)

Kring Tannert, Line; Stahl Skov, Per; Bjerremann Jensen, Louise

2012-01-01

Cold urticaria is a skin condition characterized by rapid appearance of itchy wheals and occasionally angioedema in response to cold stimulation. Antihistamines do not sufficiently protect all patients from symptoms, even when used in higher than standard doses. In these patients, desensitization...

Influence of corium oxidation on fission product release from molten pool

International Nuclear Information System (INIS)

Bechta, S.V.; Krushinov, E.V.; Vitol, S.A.

2009-01-01

Release of low-volatile fission products and core materials from molten oxidic corium was investigated in the EVAN project under the auspices of ISTC. The experiments carried out in cold crucible with induction heating and RASPLAV test facility are described. The results are discussed in terms of reactor application; in particular, pool configuration, melt oxidation kinetics, critical influence of melt surface temperature and oxidation index on the fission product release rate and aerosol particle composition. The relevance of measured high release of Sr from the molten pool for the reactor application is highlighted. Comparisons of the experimental data with those from the COLIMA CA-U3 test and the VERCORS tests, as well as with predictions from IVTANTHERMO and GEMINI/NUCLEA are set. (author)

Amelioration of cold injury-induced cortical brain edema formation by selective endothelin ETB receptor antagonists in mice.

Directory of Open Access Journals (Sweden)

Shotaro Michinaga

Full Text Available Brain edema is a potentially fatal pathological condition that often occurs in stroke and head trauma. Following brain insults, endothelins (ETs are increased and promote several pathophysiological responses. This study examined the effects of ETB antagonists on brain edema formation and disruption of the blood-brain barrier in a mouse cold injury model (Five- to six-week-old male ddY mice. Cold injury increased the water content of the injured cerebrum, and promoted extravasation of both Evans blue and endogenous albumin. In the injury area, expression of prepro-ET-1 mRNA and ET-1 peptide increased. Intracerebroventricular (ICV administration of BQ788 (ETB antagonist, IRL-2500 (ETB antagonist, or FR139317 (ETA antagonist prior to cold injury significantly attenuated the increase in brain water content. Bolus administration of BQ788, IRL-2500, or FR139317 also inhibited the cold injury-induced extravasation of Evans blue and albumin. Repeated administration of BQ788 and IRL-2500 beginning at 24 h after cold injury attenuated both the increase in brain water content and extravasation of markers. In contrast, FR139317 had no effect on edema formation when administrated after cold injury. Cold injury stimulated induction of glial fibrillary acidic protein-positive reactive astrocytes in the injured cerebrum. Induction of reactive astrocytes after cold injury was attenuated by ICV administration of BQ788 or IRL-2500. These results suggest that ETB receptor antagonists may be an effective approach to ameliorate brain edema formation following brain insults.

Low cost Czochralski crystal growing technology. Near implementation of the flat plate photovoltaic cost reduction of the low cost solar array project

Science.gov (United States)

Roberts, E. G.

1980-01-01

Equipment developed for the manufacture of over 100 kg of silicon ingot from one crucible by rechanging from another crucible is described. Attempts were made to eliminate the cost of raising the furnace temperature to 250 C above the melting point of silicon by using an RF coil to melt polycrystalline silicon rod as a means of rechanging the crucible. Microprocessor control of the straight growth process was developed and domonstrated for both 4 inch and 6 inch diameter. Both meltdown and melt stabilization processes were achieved using operator prompting through the microprocessor. The use of the RF work coil in poly rod melting as a heat sink in the accelerated growth process was unsuccessful. The total design concept for fabrication and interfacing of the total cold crucible system was completed.

Microstructure of the Ni–Fe–Cu–P melt-spun ribbons produced from the single-chamber and from the double-chamber crucibles

Energy Technology Data Exchange (ETDEWEB)

Ziewiec, Krzysztof, E-mail: kziewiec@up.krakow.pl [Institute of Technology, Faculty of Mathematics, Physics and Technical Science, Pedagogical University of Cracow, ul. Podchorążych 2, PL-30-084 Kraków (Poland); Błachowski, Artur; Ruebenbauer, Krzysztof [Mössbauer Spectroscopy Division, Institute of Physics, Pedagogical University, ul. Podchorążych 2, PL-30-084 Kraków (Poland); Ziewiec, Aneta [AGH University of Science and Technology, Faculty of Metals Engineering and Industrial Computer Science, Al. A. Mickiewicza 30, 30-059 Kraków (Poland); Prusik, Krystian [Faculty of Computer Science and Materials Science, University of Silesia, ul. Bankowa 12, PL-40-007 Katowice (Poland); Latuch, Jerzy [Warsaw University of Technology, Faculty of Materials Science and Engineering, ul. Wołoska 141, PL-02-507 Warszawa (Poland); Zięba, Marcin; Bryła, Krzysztof [Institute of Technology, Faculty of Mathematics, Physics and Technical Science, Pedagogical University of Cracow, ul. Podchorążych 2, PL-30-084 Kraków (Poland)

2014-12-05

Highlights: • A new method for production of metallic amorphous/amorphous composite is proposed. • The unique microstructure was obtained by rapid cooling of the two unmixed liquids. • The composite TCMS Ni–Fe–Cu–P amorphous alloy forms ductile fracture. - Abstract: The aim of the work was to investigate the influence of the processing on the final microstructure and properties of the melt-spun Ni–Fe–Cu–P, Ni–Fe–P and Ni–Cu–P alloys ejected in two ways. In the first case, the alloy was molten in a simple single-chamber crucible, then ejected as uniform liquid. In the second case the double-chamber crucible was used, and the flux composed of the two Ni–Fe–P and Ni–Cu–P liquids was cooled on a copper roller before forming a uniform mixture. The two component melt spinning (TCMS) was performed starting from the Ni{sub 40}Fe{sub 40}P{sub 20} and Ni{sub 70}Cu{sub 10}P{sub 20} alloys. Three of the alloys i.e. Ni{sub 55}Fe{sub 20}Cu{sub 4}P{sub 20}, Ni{sub 40}Fe{sub 40}P{sub 20} and Ni{sub 70}Cu{sub 10}P{sub 20} were melt-spun from the traditional single-chamber crucible. The methods applied in this study for microstructural investigations include scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and Mössbauer spectroscopy. Thermal stability of the melt-spun alloys was tested using differential scanning calorimetry (DSC). The results of the investigations are described and discussed in terms of the unique features of the TCMS amorphous microstructure. It is shown that this complex phase composition of the amorphous alloy favors formation of the ductile fracture and the multiple shear band formation.

Development of advanced Czochralski Growth Process to produce low cost 150 KG silicon ingots from a single crucible for technology readiness

Science.gov (United States)

1981-01-01

The goals in this program for advanced czochralski growth process to produce low cost 150 kg silicon ingots from a single crucible for technology readiness are outlined. To provide a modified CG2000 crystal power capable of pulling a minimum of five crystals, each of approximately 30 kg in weight, 150 mm diameter from a single crucible with periodic melt replenishment. Crystals to have: resistivity of 1 to 3 ohm cm, p-type; dislocation density below 1- to the 6th power per cm; orientation (100); after growth yield of greater than 90%. Growth throughput of greater than 2.5 kg per hour of machine operation using a radiation shield. Prototype equipment suitable for use as a production facility. The overall cost goal is $.70 per peak watt by 1986. To accomplish these goals, the modified CG2000 grower and development program includes: (1) increased automation with a microprocessor based control system; (2) sensors development which will increase the capability of the automatic controls system, and provide technology transfer of the developed systems.

A constant flux of diverse thermophilic bacteria into the cold arctic seabed

DEFF Research Database (Denmark)

Hubert, Casey; Loy, Alexander; Nickel, Maren

2009-01-01

Microorganisms have been repeatedly discovered in environments that do not support their metabolic activity. Identifying and quantifying these misplaced organisms can reveal dispersal mechanisms that shape natural microbial diversity. Using endospore germination experiments, we estimated a stable...... supply of thermophilic bacteria into permanently cold Arctic marine sediment at a rate exceeding 108 spores per square meter per year. These metabolically and phylogenetically diverse Firmicutes show no detectable activity at cold in situ temperatures but rapidly mineralize organic matter by hydrolysis......, fermentation, and sulfate reduction upon induction at 50°C. The closest relatives to these bacteria come from warm subsurface petroleum reservoir and ocean crust ecosystems, suggesting that seabed fluid flow from these environments is delivering thermophiles to the cold ocean. These transport pathways may...

Initiating the Validation of CCIM Processability for Multi-phase all Ceramic (SYNROC) HLW Form: Plan for Test BFY14CCIM-C

Energy Technology Data Exchange (ETDEWEB)

Maio, Vince [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2014-08-01

This plan covers test BFY14CCIM-C which will be a first–of–its-kind demonstration for the complete non-radioactive surrogate production of multi-phase ceramic (SYNROC) High Level Waste Forms (HLW) using Cold Crucible Induction Melting (CCIM) Technology. The test will occur in the Idaho National Laboratory’s (INL) CCIM Pilot Plant and is tentatively scheduled for the week of September 15, 2014. The purpose of the test is to begin collecting qualitative data for validating the ceramic HLW form processability advantages using CCIM technology- as opposed to existing ceramic–lined Joule Heated Melters (JHM) currently producing BSG HLW forms. The major objectives of BFY14CCIM-C are to complete crystalline melt initiation with a new joule-heated resistive starter ring, sustain inductive melting at temperatures between 1600 to 1700°C for two different relatively high conductive materials representative of the SYNROC ceramic formation inclusive of a HLW surrogate, complete melter tapping and pouring of molten ceramic material in to a preheated 4 inch graphite canister and a similar canister at room temperature. Other goals include assessing the performance of a new crucible specially designed to accommodate the tapping and pouring of pure crystalline forms in contrast to less recalcitrant amorphous glass, assessing the overall operational effectiveness of melt initiation using a resistive starter ring with a dedicated power source, and observing the tapped molten flow and subsequent relatively quick crystallization behavior in pans with areas identical to standard HLW disposal canisters. Surrogate waste compositions with ceramic SYNROC forming additives and their measured properties for inductive melting, testing parameters, pre-test conditions and modifications, data collection requirements, and sampling/post-demonstration analysis requirements for the produced forms are provided and defined.

Comparison of glassy slag waste forms produced in laboratory crucibles and in a bench-scale plasma furnace

International Nuclear Information System (INIS)

Feng, X.; Wronkiewicz, D.J.; Brown, N.R.; Gong, M.; Whitworth, C.; Filius, K.; Battleson, D.

1994-01-01

Vitrification is currently the best demonstrated available technology for the disposal of high-level radioactive wastes. An innovative vitrification approach known as minimum additive waste stabilization (MAWS) is being developed. Both homogeneous glass and glassy slags have been used in implementing MAWS. Glassy slags (vitro-ceramics) are glass-crystal composites, and they are composed of various metal oxide crystalline phases embedded in an aluminosilicate glass matrix. Glassy slags with compositions developed in crucible melts at Argonne National Laboratory (ANL) were successfully produced in a bench-scale Retech plasma centrifugal furnace (PCF) by MSE, Inc. Detailed examinations of these materials showed that the crucible melts and the PCF produced similar glass and crystalline phases. The two sets of glassy slags exhibited similar chemical durability in terms of normalized releases of their major components. The slags produced in the PCF furnace using metals were usually less oxidized, although this had no effect on the corrosion behavior of the major components of the slags. However, the normalized release rate of cerium was initially lower for the PCF slags. This difference diminished with time as the redox sates of the metal oxides in slags began to be controlled by exposure to air in the tests. Thus, the deference in cerium release due to the differences in slag redox state may be transitory. The cerium solubility is a complex function of redox state and solution pH and Eh

Field protocol for induction of triploidy in Clarias gariepinus | Nwafili ...

African Journals Online (AJOL)

A simple field protocol for induction of triploidy in Clarias gariepinus using cold shock was developed. The quantity of ice needed to bring temperature of water down to desired temperature was first calculated. Fertilized eggs were then exposed to 5 ºC or 10 ºC at different times. Percentage hatchability for 5 ºC fertilized ...

Contactless Ultrasound Generation in a Crucible

Science.gov (United States)

Bojarevics, Valdis; Djambazov, Georgi S.; Pericleous, Koulis A.

2015-07-01

Ultrasound treatment is used in light alloys during solidification to refine microstructure, remove gas, or disperse immersed particles. A mechanical sonotrode immersed in the melt is most effective when probe tip vibrations lead to cavitation. Liquid contact with the probe can be problematic for high temperature or reactive melts leading to contamination. An alternative contactless method of generating ultrasonic waves is proposed, using electromagnetic (EM) induction. As a bonus, the EM force induces vigorous stirring distributing the effect to treat larger volumes of material. In a typical application, the induction coil surrounding the crucible—also used to melt the alloy—may be adopted for this purpose with suitable tuning. Alternatively, a top coil, immersed in the melt (but still contactless due to EM force repulsion) may be used. Numerical simulations of sound, flow, and EM fields suggest that large pressure amplitudes leading to cavitation may be achievable with this method.

Continuous Czochralski growth. Development of advanced Czochralski growth process to produce low cost 150 kg silicon ingots from a single crucible for technology readiness

Science.gov (United States)

The improvement of growth rates using radiation shielding and investigation of the crucible melt interaction for improved yields were emphasized. Growth runs were performed from both 15 and 16 inch diameter crucibles, producing 30 and 37 kg ingots respectively. Efforts to increase the growth rate of 150 mm diameter ingots were limited by temperature instabilities believed to be caused by undesirable thermal convections in the larger melts. The radiation shield improved the growth rate somewhat, but the thermal instability was still evident, leading to nonround ingots and loss of dislocation-free structure. A 38 kg crystal was grown to demonstrate the feasibility of producing 150 kg with four growth cycles. After the grower construction phase, the Hamco microprocessor control system was interfaced to the growth facility, including the sensor for automatic control of seeding temperature, and the sensor for automatic shouldering. Efforts focused upon optimization of the seeding, necking, and shoulder growth automation programs.

Influence of Crucible Support Rod on the Growth Rate and Temperature Gradient in a Bridgman Growth of Tin Crystal

OpenAIRE

IMASHIMIZU, Yuji; MIURA, Koji; KAMATA, Masaki; WATANABE, Jiro

2003-01-01

Bridgman growth of tincrystal was carried out in a graphite crucible that was fixed on a quartz support rod or a copper one. The growth rate and axial temperature distribution were examined by recording the temperature variation with time at each of four prescribed positions in the solid-liquidsystem during solidification, l) Actual growth rate of crystal increased with progress of solidification while the furnace elevated at a constant rate, but the tendency was different depending on the ty...

Detection of cold pain, cold allodynia and cold hyperalgesia in freely behaving rats

Directory of Open Access Journals (Sweden)

Woolf Clifford J

2005-12-01

Full Text Available Abstract Background Pain is elicited by cold, and a major feature of many neuropathic pain states is that normally innocuous cool stimuli begin to produce pain (cold allodynia. To expand our understanding of cold induced pain states we have studied cold pain behaviors over a range of temperatures in several animal models of chronic pain. Results We demonstrate that a Peltier-cooled cold plate with ± 1°C sensitivity enables quantitative measurement of a detection withdrawal response to cold stimuli in unrestrained rats. In naïve rats the threshold for eliciting cold pain behavior is 5°C. The withdrawal threshold for cold allodynia is 15°C in both the spared nerve injury and spinal nerve ligation models of neuropathic pain. Cold hyperalgesia is present in the spared nerve injury model animals, manifesting as a reduced latency of withdrawal response threshold at temperatures that elicit cold pain in naïve rats. We also show that following the peripheral inflammation produced by intraplantar injection of complete Freund's adjuvant, a hypersensitivity to cold occurs. Conclusion The peltier-cooled provides an effective means of assaying cold sensitivity in unrestrained rats. Behavioral testing of cold allodynia, hyperalgesia and pain will greatly facilitate the study of the neurobiological mechanisms involved in cold/cool sensations and enable measurement of the efficacy of pharmacological treatments to reduce these symptoms.

Tank waste remediation system high-level waste vitrification system development and testing requirements

International Nuclear Information System (INIS)

Calmus, R.B.

1995-01-01

This document provides the fiscal year (FY) 1995 recommended high-level waste melter system development and testing (D and T) requirements. The first phase of melter system testing (FY 1995) will focus on the feasibility of high-temperature operation of recommended high-level waste melter systems. These test requirements will be used to establish the basis for defining detailed testing work scope, cost, and schedules. This document includes a brief summary of the recommended technologies and technical issues associated with each technology. In addition, this document presents the key D and T activities and engineering evaluations to be performed for a particular technology or general melter system support feature. The strategy for testing in Phase 1 (FY 1995) is to pursue testing of the recommended high-temperature technologies, namely the high-temperature, ceramic-lined, joule-heated melter, referred to as the HTCM, and the high-frequency, cold-wall, induction-heated melter, referred to as the cold-crucible melter (CCM). This document provides a detailed description of the FY 1995 D and T needs and requirements relative to each of the high-temperature technologies

Induction of triploidy and tetraploidy in Nile tilapia, Oreochromis niloticus (L.)

Science.gov (United States)

El Gamal, A.-R.A.; Davis, K.B.; Jenkins, J.A.; Les, Torrans E.

1999-01-01

Induction of triploidy and tetraploidy in Nile tilapia, Oreochromis niloticus, was investigated by heat shock, cold shock, hydrostatic pressure, and/ or chemicals (cytochalasin A, B, and D). Additionally, efficacy of combined protocols was determined. Heat shock 10 min after fertilization induced triploidy when incubation temperature was 24 C but not when incubation temperature was 31 C. Heat shock of 40-41 C at 4-6 min after fertilization was effective in inducing up to 100% triploidy with hatchability similar to controls. Cold shock at 13 C for 45 min five min after fertilization induced 85-100% triploids. Heat shock and multiple heat shocking were the most effective treatments for the induction of tetraploidy. Two heat treatments of 41 C applied at 65 and 80 min after fertilization for 5 min each produced approximately 80% tetraploidy in hatched fry. Immersion of fertilized eggs in cytochalasin A, B, or D at concentrations up to 10 ??g/L applied at various times and durations was ineffective in inducing triploidy or tetraploidy.

Crystallization of nuclear glass under a thermal gradient: application to the self-crucible produced in the skull melting process

International Nuclear Information System (INIS)

Delattre, O.

2013-01-01

In the context of the vitrification of high level nuclear waste, a new industrial process has been launched in 2010 at the La Hague factory: The skull melting process. This setup applies thermal gradients to the melt, which leads to the formation of a solid layer of glass: the 'self-crucible'. The question would be to know whether these thermal gradients have an impact or not on the crystallization behaviour of the considered glasses in the self crucible. In order to answer that question, the crystallization of two glass compositions of nuclear interest has been investigated with an image analysis based method in isothermal and thermal gradient heat treatments conditions. The isothermal experiments allow for the quantification (growth speed, nucleation, crystallized fraction) of the crystallization of apatites (660 C-900 C) and powellites (630 C-900 C). The comparison of the results obtained through these two types of experimentations allows us to conclude that there is no impact of the thermal gradient on the crystallization of the studied glass compositions. In order to complete the image analysis study (based on surfaces), in and ex situ microtomography experiments have been performed at ESRF (Grenoble) on the ID19 beamline. This study allowed us to follow the crystallization of apatites in a simplified glass and to confirm the reliability of the image analysis method based on the analysis of surfaces. (author) [fr

A new hybrid two-zone/crucible furnace process for the growth of epitaxial Tl{sub 2}Ba{sub 2}CaCu{sub 2}O{sub 8} superconducting films

Energy Technology Data Exchange (ETDEWEB)

Siegal, M.P.; Overmyer, D.L.; Venturini, E.L.; Dominguez, F.; Padilla, R.R. [Sandia National Laboratories, Albuquerque, New Mexico 87185-1421 (United States)

1998-12-01

Epitaxial Tl{sub 2}Ba{sub 2}CaCu{sub 2}O{sub 8} (Tl-2212) films {approximately}5500 {Angstrom} thick are grown on LaAlO{sub 3}(100) substrates using a new hybrid two-zone/crucible furnace process enabling precise control of thallination. This method combines the best features of both conventional crucible and two-zone processing for the first time: superb film properties and reduced handling of hazardous Tl-oxide powders. Single-phase, highly {ital c}-axis oriented Tl-2212 films are grown with smooth morphology, Meissner transition {approximately}103 K, and critical current density {approximately}1.1{times}10{sup 7}A/cm{sup 2} at 5 K for twenty consecutive runs without having to change or add to the Tl-oxide source. {copyright} {ital 1998 Materials Research Society.}

Determination of mercury in coal by isotope dilution cold-vapor generation inductively coupled plasma mass spectrometry

Energy Technology Data Exchange (ETDEWEB)

Long, S.E.; Kelly, W.R.

2002-04-01

A method based on isotope dilution cold-vapor inductively coupled plasma mass spectrometry (ID-CV-ICPMS) has been developed for high-accuracy determinations of mercury in bituminous and sub-bituminous coals. A closed-system digestion process employing a Carius tube is used to completely oxidize the coal matrix and chemically equilibrate the mercury in the sample with a Hg-201 isotopic spike. The digestates are diluted with high-purity quartz-distilled water, and the mercury is released as a vapor by reduction with tin chloride. Measurements of Hg-201/Hg-202 isotope ratios are made using a quadrupole ICPMS system in time-resolved analysis mode. The new method has some significant advantages over existing methods. The instrument detection limit is less than 1 pg/mL. The average blank (n = 17) is 30 pg, which is roughly 1 order of magnitude lower than the equivalent microwave digestion procedure. The detection limit in coal is blank limited and is similar to 40 pg/g. Memory effects are very low. The relative reproducibility of the analytical measurements is similar to 0.5% for mercury concentrations in the range 10-150 ng/g. The method has been used to measure mercury concentrations in six coal reference materials, SRM 1632b (77.4 ng/g), SRM 1632c (94.3 ng/g), BCR 40 (433.2 ng/g), BCR 180 (125.0 ng/g), BCR 181 (135.8 ng/g), and SARM 20 (252.6 ng/g), as well as a coal fly ash, SRM 1633b (143.1 ng/g). The method is equally applicable to other types of fossil fuels including both crude and refined oils.

The protective effect of rapid cold-hardening develops more quickly in frozen versus supercooled larvae of the Antarctic midge, Belgica antarctica.

Science.gov (United States)

Kawarasaki, Yuta; Teets, Nicholas M; Denlinger, David L; Lee, Richard E

2013-10-15

During the austral summer, larvae of the terrestrial midge Belgica antarctica (Diptera: Chironomidae) experience highly variable and often unpredictable thermal conditions. In addition to remaining freeze tolerant year-round, larvae are capable of swiftly increasing their cold tolerance through the rapid cold-hardening (RCH) response. The present study compared the induction of RCH in frozen versus supercooled larvae. At the same induction temperature, RCH occurred more rapidly and conferred a greater level of cryoprotection in frozen versus supercooled larvae. Furthermore, RCH in frozen larvae could be induced at temperatures as low as -12°C, which is the lowest temperature reported to induce RCH. Remarkably, as little as 15 min at -5°C significantly enhanced larval cold tolerance. Not only is protection from RCH acquired swiftly, but it is also quickly lost after thawing for 2 h at 2°C. Because the primary difference between frozen and supercooled larvae is cellular dehydration caused by freeze concentration of body fluids, we also compared the effects of acclimation in dehydrated versus frozen larvae. Because slow dehydration without chilling significantly increased larval survival to a subsequent cold exposure, we hypothesize that cellular dehydration caused by freeze concentration promotes the rapid acquisition of cold tolerance in frozen larvae.

Lipocalin 2 regulation by thermal stresses: Protective role of Lcn2/NGAL against cold and heat stresses

International Nuclear Information System (INIS)

Roudkenar, Mehryar Habibi; Halabian, Raheleh; Roushandeh, Amaneh Mohammadi; Nourani, Mohammad Reza; Masroori, Nasser; Ebrahimi, Majid; Nikogoftar, Mahin; Rouhbakhsh, Mehdi; Bahmani, Parisa; Najafabadi, Ali Jahanian; Shokrgozar, Mohammad Ali

2009-01-01

Environmental temperature variations are the most common stresses experienced by a wide range of organisms. Lipocalin 2 (Lcn2/NGAL) is expressed in various normal and pathologic conditions. However, its precise functions have not been fully determined. Here we report the induction of Lcn2 by thermal stresses in vivo, and its role following exposure to cold and heat stresses in vitro. Induction of Lcn2 in liver, heart and kidney was detected by RT-PCR, Western blot and immunohistochemistry following exposure of mice to heat and cold stresses. When CHO and HEK293T cells overexpressing NGAL were exposed to cold stress, cell proliferation was higher compared to controls. Down-regulatrion of NGAL by siRNA in A549 cells resulted in less proliferation when exposed to cold stress compared to control cells. The number of apoptotic cells and expression of pro-apoptotic proteins were lower in the NGAL overexpressing CHO and HEK293T cells, but were higher in the siRNA-transfected A549 cells compared to controls, indicating that NGAL protects cells against cold stress. Following exposure of the cells to heat stress, ectopic expression of NGAL protected cells while addition of exogenous recombinant NGAL to the cell culture medium exacerbated the toxicity of heat stress specially when there was low or no endogenous expression of NGAL. It had a dual effect on apoptosis following heat stress. NGAL also increased the expression of HO-1. Lcn2/NGAL may have the potential to improve cell proliferation and preservation particularly to prevent cold ischemia injury of transplanted organs or for treatment of some cancers by hyperthermia.

Lipocalin 2 regulation by thermal stresses: Protective role of Lcn2/NGAL against cold and heat stresses

Energy Technology Data Exchange (ETDEWEB)

Roudkenar, Mehryar Habibi, E-mail: roudkenar@ibto.ir [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Halabian, Raheleh [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Roushandeh, Amaneh Mohammadi [Department of Anatomy, Faculty of Medicine, Medical University of Tabriz, Tabriz (Iran, Islamic Republic of); Nourani, Mohammad Reza [Chemical Injury Research Center, Baqiyatallah Medical Science University, Tehran (Iran, Islamic Republic of); Masroori, Nasser [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Ebrahimi, Majid [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Chemical Injury Research Center, Baqiyatallah Medical Science University, Tehran (Iran, Islamic Republic of); Nikogoftar, Mahin; Rouhbakhsh, Mehdi; Bahmani, Parisa [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Najafabadi, Ali Jahanian [Department of Molecular Biology, Pasteur Institute of Iran, Tehran (Iran, Islamic Republic of); Shokrgozar, Mohammad Ali [National Cell Bank of Iran, Pasteur institute of Iran, Tehran (Iran, Islamic Republic of)

2009-11-01

Environmental temperature variations are the most common stresses experienced by a wide range of organisms. Lipocalin 2 (Lcn2/NGAL) is expressed in various normal and pathologic conditions. However, its precise functions have not been fully determined. Here we report the induction of Lcn2 by thermal stresses in vivo, and its role following exposure to cold and heat stresses in vitro. Induction of Lcn2 in liver, heart and kidney was detected by RT-PCR, Western blot and immunohistochemistry following exposure of mice to heat and cold stresses. When CHO and HEK293T cells overexpressing NGAL were exposed to cold stress, cell proliferation was higher compared to controls. Down-regulatrion of NGAL by siRNA in A549 cells resulted in less proliferation when exposed to cold stress compared to control cells. The number of apoptotic cells and expression of pro-apoptotic proteins were lower in the NGAL overexpressing CHO and HEK293T cells, but were higher in the siRNA-transfected A549 cells compared to controls, indicating that NGAL protects cells against cold stress. Following exposure of the cells to heat stress, ectopic expression of NGAL protected cells while addition of exogenous recombinant NGAL to the cell culture medium exacerbated the toxicity of heat stress specially when there was low or no endogenous expression of NGAL. It had a dual effect on apoptosis following heat stress. NGAL also increased the expression of HO-1. Lcn2/NGAL may have the potential to improve cell proliferation and preservation particularly to prevent cold ischemia injury of transplanted organs or for treatment of some cancers by hyperthermia.

Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism

DEFF Research Database (Denmark)

Hao, Qin; Yadav, Rachita; Basse, Astrid L.

2015-01-01

We applied digital gene expression profiling to determine the transcriptome of brown and white adipose tissues (BAT and WAT, respectively) during cold exposure. Male C57BL/6J mice were exposed to cold for 2 or 4 days. A notable induction of genes related to glucose uptake, glycolysis, glycogen...... exposure, we propose a model for the intermediary glucose metabolism in activated BAT: 1) fluxes through glycolysis and the pentose phosphate pathway are induced, the latter providing reducing equivalents for de novo fatty acid synthesis; 2) glycerol synthesis from glucose is increased, facilitating...

Utilization of Space Shuttle External Tank materials by melting and powder metallurgy

Science.gov (United States)

Chern, T. S.

1985-01-01

The Crucible Melt Extraction Process was demonstrated to convert scraps of aluminum alloy 2219, used in the Space Shuttle External Tank, into fibers. The cast fibers were then consolidated by cold welding. The X-ray diffraction test of the cast fibers was done to examine the crystallinity and oxide content of the fibers. The compressive stress-strain behavior of the consolidated materials was also examined. Two conceptual schemes which would adapt the as-developed Crucible Melt Extraction Process to the microgravity condition in space were finally proposed.

Bending Distortion Analysis of a Steel Shaft Manufacturing Chain from Cold Drawing to Grinding

Science.gov (United States)

Dias, Vinicius Waechter; da Silva Rocha, Alexandre; Zottis, Juliana; Dong, Juan; Epp, Jérémy; Zoch, Hans Werner

2017-04-01

Shafts are usually manufactured from bars that are cold drawn, cut machined, induction hardened, straightened, and finally ground. The main distortion is characterized by bending that appears after induction hardening and is corrected by straightening and/or grinding. In this work, the consequence of the variation of manufacturing parameters on the distortion was analyzed for a complete manufacturing route for production of induction hardened shafts made of Grade 1045 steel. A DoE plan was implemented varying the drawing angle, cutting method, induction hardening layer depth, and grinding penetration depth. The distortion was determined by calculating curvature vectors from dimensional analysis by 3D coordinate measurements. Optical microscopy, microhardness testing, residual stress analysis, and FEM process simulation were used to evaluate and understand effects of the main carriers of distortion potential. The drawing process was identified as the most significant influence on the final distortion of the shafts.

Radioactive waste combustion-vitrification under arc plasma: thermal and dynamic modelling

International Nuclear Information System (INIS)

Barthelemy, B.

2003-06-01

This thesis concerns the thermal and dynamic modelling for a combustion/vitrification process of surrogate radioactive waste under transferred arc plasma. The writer presents the confinement processes for radioactive waste using arc plasma and the different software used to model theses processes. This is followed by a description of our experimental equipment including a plasma arc reactor and an inductive system allowing the homogenization of glass temperature. A combustion/vitrification test is described. Thermal and material balances were discussed. The temperature fields of plasma arc and the glass frit conductivity are measured. Finally, the writer describes and clarifies the equations solved for the simulations of the electrically plasma arc and the glass melting including the thin layer of glass frit coating the crucible cold walls. The modelling results are presented in the form of spatial distribution of temperature, velocity and voluminal power... (author)

Radioactive waste combustion / vitrification under arc plasma: thermal and dynamic modelling

International Nuclear Information System (INIS)

Barthelemy, B.

2003-01-01

This thesis concerns the thermal and dynamic modelling for a combustion/vitrification process of surrogate radioactive waste under transferred arc plasma. The writer presents the confinement processes for radioactive waste using arc plasma and the different software used to model theses processes. This is followed by a description of our experimental equipment including a plasma arc reactor and an inductive system allowing the homogenization of glass temperature. A combustion/vitrification test is described. Thermal and material balances were discussed. The temperature fields of plasma arc and the glass frit conductivity are measured. Finally, the writer describes and clarifies the equations solved for the simulations of the electrically plasma arc and the glass melting including the thin layer of glass frit coating the crucible cold walls. The modelling results are presented in the form of spatial distribution of temperature, velocity and volume power... (author)

Radioactive waste combustion / vitrification under arc plasma: thermal and dynamic modelling; Combustion - vitrification de dechets radioactifs par plasma d'arc: modelisation de la thermique et de la dynamique

Energy Technology Data Exchange (ETDEWEB)

Barthelemy, B

2003-07-01

This thesis concerns the thermal and dynamic modelling for a combustion/vitrification process of surrogate radioactive waste under transferred arc plasma. The writer presents the confinement processes for radioactive waste using arc plasma and the different software used to model theses processes. This is followed by a description of our experimental equipment including a plasma arc reactor and an inductive system allowing the homogenization of glass temperature. A combustion/vitrification test is described. Thermal and material balances were discussed. The temperature fields of plasma arc and the glass frit conductivity are measured. Finally, the writer describes and clarifies the equations solved for the simulations of the electrically plasma arc and the glass melting including the thin layer of glass frit coating the crucible cold walls. The modelling results are presented in the form of spatial distribution of temperature, velocity and volume power... (author)

Radioactive waste combustion-vitrification under arc plasma: thermal and dynamic modelling; Combustion - vitrification de dechets radioactifs par plasma d'arc: modelisation de la thermique et de la dynamique

Energy Technology Data Exchange (ETDEWEB)

Barthelemy, B

2003-06-01

This thesis concerns the thermal and dynamic modelling for a combustion/vitrification process of surrogate radioactive waste under transferred arc plasma. The writer presents the confinement processes for radioactive waste using arc plasma and the different software used to model theses processes. This is followed by a description of our experimental equipment including a plasma arc reactor and an inductive system allowing the homogenization of glass temperature. A combustion/vitrification test is described. Thermal and material balances were discussed. The temperature fields of plasma arc and the glass frit conductivity are measured. Finally, the writer describes and clarifies the equations solved for the simulations of the electrically plasma arc and the glass melting including the thin layer of glass frit coating the crucible cold walls. The modelling results are presented in the form of spatial distribution of temperature, velocity and voluminal power... (author)

Melting of glass by direct induction heating in ceramic container

International Nuclear Information System (INIS)

Ooka, Kazuo; Oguino, Naohiko; Kawanishi, Nobuo

1981-01-01

The direct induction melting, a process of glass melting by high frequency induction heating, was found to be the effective way of glass melting, especially desirable for the vitrification of High Level Radioactive Liquid Wastes, HLLW. A test instrument in the cold level was equipped with a high frequency oscillator of 65 kW anode output. The direct induction melting was successfully performed with two frequencies of 400 kHz and 3 MHz, and the operation conditions were determined in the five cases of ceramic pot inner diameters of 170, 200, 230, 280 and 325 mm. The start-up of the direct induction melting was carried out by induction heating using a silicon carbide rod which was inserted in raw material powders in the ceramic pot. After the raw material powders partly melted down and the direct induction in the melt began, the start-up rod was removed out of the melt. At this stage, the direct induction melting was successively performed by adjusting the output power of the oscillator and by supplying the raw materials. It was also found that the capacity of this type of melting was reasonably large and the operation could be remotely controlled. Both applied frequencies of 400 kHz and 3 MHz was found to be successful with this melting system, especially in the case of lower frequency which proved more preferable for the in-cell work. (author)

Study on modes of energy action in laser-induction hybrid cladding

International Nuclear Information System (INIS)

Huang Yongjun; Zeng Xiaoyan

2009-01-01

The shape and microstructure in laser-induction hybrid cladding were investigated, in which the cladding material was provided by means of three different methods including the powder feeding, cold pre-placed coating (CPPC) and thermal pre-placed coating (TPPC). Moreover, the modes of energy action in laser-induction hybrid cladding were also studied. The results indicate that the cladding material supplying method has an important influence on the shape and microstructure of coating. The influence is decided by the mode of energy action in laser-induction hybrid cladding. During the TPPC hybrid cladding of Ni-based alloy, the laser and induction heating are mainly performed on coating. During the CPPC hybrid cladding of Ni-based alloy, the laser and induction heating are mainly performed on coating and substrate surface, respectively. In powder feeding hybrid cladding, a part of laser is absorbed by the powder particles directly, while the other part of laser penetrating powder cloud radiates on the molten pool. Meanwhile, the induction heating is entirely performed on the substrate. In addition, the wetting property on the interface is improved and the metallurgical bond between the coating and substrate is much easier to form. Therefore, the powder feeding laser-induction hybrid cladding has the highest cladding efficiency and the best bond property among three hybrid cladding methods.

Application of the Rutherford backscattering analysis (RBS analysis) for detecting heavy impurity elements in pBN crucible materials

International Nuclear Information System (INIS)

Bethge, K.; Meyer, J.D.; Michelmann, R.; Krauskopf, J.

1992-01-01

By means of the Rutherford backscattering analysis evidence is given of an inhomogeneous depth distribution of the elements C, O, F, Na, Mg, Al, Si, P, S, Cl, Ca, Ti, Cr, Fe, Ni in pBN (pyrolytic boron nitride) materials of crucibles. This inhomogenous distribution is observed both at the original surface and at the surface of inner cracks. In addition, the distribution of the elements is found to differ depending on the spots chosen for analysis. The RBS measurements alone do not yield information on the volume concentration of the elements. (orig.) With 2 refs [de

How cold is cold dark matter?

International Nuclear Information System (INIS)

Armendariz-Picon, Cristian; Neelakanta, Jayanth T.

2014-01-01

If cold dark matter consists of particles, these must be non-interacting and non-relativistic by definition. In most cold dark matter models however, dark matter particles inherit a non-vanishing velocity dispersion from interactions in the early universe, a velocity that redshifts with cosmic expansion but certainly remains non-zero. In this article, we place model-independent constraints on the dark matter temperature to mass ratio, whose square root determines the dark matter velocity dispersion. We only assume that dark matter particles decoupled kinetically while non-relativistic, when galactic scales had not entered the horizon yet, and that their momentum distribution has been Maxwellian since that time. Under these assumptions, using cosmic microwave background and matter power spectrum observations, we place upper limits on the temperature to mass ratio of cold dark matter today (away from collapsed structures). These limits imply that the present cold dark matter velocity dispersion has to be smaller than 54 m/s. Cold dark matter has to be quite cold, indeed

Cold Antimatter Plasmas, and Aspirations for Cold Antihydrogen

Science.gov (United States)

2002-06-24

UNCLASSIFIED Defense Technical Information Center Compilation Part Notice ADP012494 TITLE: Cold Antimatter Plasmas, and Aspirations for Cold...part numbers comprise the compilation report: ADP012489 thru ADP012577 UNCLASSIFIED Cold Antimatter Plasmas, and Aspirations for Cold Antihydrogen G...and positrons. The antiprotons come initially from the new Antiproton Decel- erator facility at CERN. Good control of such cold antimatter plasmas is

Fructan metabolism and changes in fructan composition during cold acclimation in perennial ryegrass

Science.gov (United States)

Abeynayake, Shamila W.; Etzerodt, Thomas P.; Jonavičienė, Kristina; Byrne, Stephen; Asp, Torben; Boelt, Birte

2015-01-01

Perennial ryegrass (Lolium perenne L.) produces high levels of fructans as a mixture of oligosaccharides and polysaccharides with different degrees of polymerization (DP). The present study describes the analysis of the compositional changes in the full spectrum of fructans, fructan distribution between above ground biomass (top) and the roots, and the transcription of candidate genes involved in fructan metabolism during cold acclimation in perennial ryegrass variety “Veyo” and ecotype “Falster” from distinct geographical origins. We observed changes in fructan composition and induction of low-DP fructans, especially DP = 4, in both the top and the roots of “Veyo” and “Falster” in response to low-temperature stress. The accumulation of DP > 50 fructans was only apparent in the top tissues where the Lp1-FFT expression is higher compared to the roots in both “Veyo” and “Falster.” Our results also show the accumulation and depolymerization of fructans with different DP, together with the induction of genes encoding fructosyltransferases and fructan exohydrolases in both “Veyo” and “Falster” during cold acclimation, supporting the hypothesis that fructan synthesis and depolymerization occurring simultaneously. The ecotype “Falster,” adapted to cold climates, increased total fructan content and produced more DP > 7 fructans in the roots than the variety “Veyo,” adapted to warmer climates. This indicates that high-DP fructan accumulation in roots may be an adaptive trait for plant recovery after abiotic stresses. PMID:26029229

Determination of temperature and pressure in the calcium reduction process

International Nuclear Information System (INIS)

Arceri, Mariana E.

1997-01-01

The calcium reduction process consists in the reduction of uranium tetrafluoride (UF 4 ) with calcium in a refractory material crucible, in order to obtain metallic uranium. The crucible is in turn contained in a steel reactor, heated by means of an induction coil to bring the reagents from the environmental temperature to the temperature necessary for the reaction starting. For the design of the reactor, mathematical expressions that allow to estimate the temperature and pressure of the system have been developed

An alternative to the traditional cold pressor test: the cold pressor arm wrap.

Science.gov (United States)

Porcelli, Anthony John

2014-01-16

Recently research on the relationship between stress and cognition, emotion, and behavior has greatly increased. These advances have yielded insights into important questions ranging from the nature of stress' influence on addiction(1) to the role of stress in neural changes associated with alterations in decision-making(2,3). As topics being examined by the field evolve, however, so too must the methodologies involved. In this article a practical and effective alternative to a classic stress induction technique, the cold pressor test (CPT), is presented: the cold pressor arm wrap (CPAW). CPT typically involves immersion of a participant's dominant hand in ice-cold water for a period of time(4). The technique is associated with robust activation of the sympatho-adrenomedullary (SAM) axis (and release of catecholamines; e.g. adrenaline and noradrenaline) and mild-to-moderate activation of the hypothalamic-pituitary-adrenal (HPA) axis with associated glucocorticoid (e.g. cortisol) release. While CPT has been used in a wide range of studies, it can be impractical to apply in some research environments. For example use of water during, rather than prior to, magnetic resonance imaging (MRI) has the potential to damage sensitive and expensive equipment or interfere with acquisition of MRI signal. The CPAW is a practical and effective alternative to the traditional CPT. Composed of a versatile list of inexpensive and easily acquired components, CPAW makes use of MRI-safe gelpacs cooled to a temperature similar to CPT rather than actual water. Importantly CPAW is associated with levels of SAM and HPA activation comparable to CPT, and can easily be applied in a variety of research contexts. While it is important to maintain specific safety protocols when using the technique, these are easy to implement if planned for. Creation and use of the CPAW will be discussed.

Hypothermic general cold adaptation induced by local cold acclimation.

Science.gov (United States)

Savourey, G; Barnavol, B; Caravel, J P; Feuerstein, C; Bittel, J H

1996-01-01

To study relationships between local cold adaptation of the lower limbs and general cold adaptation, eight subjects were submitted both to a cold foot test (CFT, 5 degrees C water immersion, 5 min) and to a whole-body standard cold air test (SCAT, 1 degree C, 2 h, nude at rest) before and after a local cold acclimation (LCA) of the lower limbs effected by repeated cold water immersions. The LCA induced a local cold adaptation confirmed by higher skin temperatures of the lower limbs during CFT and a hypothermic insulative general cold adaptation (decreased rectal temperature and mean skin temperature P adaptation was related to the habituation process confirmed by decreased plasma concentrations of noradrenaline (NA) during LCA (P general cold adaptation was unrelated either to local cold adaptation or to the habituation process, because an increased NA during SCAT after LCA (P syndrome" occurring during LCA.

The induction of menadione stress tolerance in the marine microalga, Dunaliella viridis, through cold pretreatment and modulation of the ascorbate and glutathione pools.

Science.gov (United States)

Madadkar Haghjou, Maryam; Colville, Louise; Smirnoff, Nicholas

2014-11-01

The effect of cold pretreatment on menadione tolerance was investigated in the cells of the marine microalga, Dunaliella viridis. In addition, the involvement of ascorbate and glutathione in the response to menadione stress was tested by treating cell suspensions with l-galactono-1,4-lactone, an ascorbate precursor, and buthionine sulfoximine, an inhibitor of glutathione synthesis. Menadione was highly toxic to non cold-pretreated cells, and caused a large decrease in cell number. Cold pretreatment alleviated menadione toxicity and cold pretreated cells accumulated lower levels of reactive oxygen species, and had enhanced antioxidant capacity due to increased levels of β-carotene, reduced ascorbate and total glutathione compared to non cold-pretreated cells. Cold pretreatment also altered the response to l-galactono-1,4-lactone and buthionine sulfoximine treatments. Combined l-galactono-1,4-lactone and menadione treatment was lethal in non-cold pretreated cells, but in cold-pretreated cells it had a positive effect on cell numbers compared to menadione alone. Overall, exposure of Dunaliella cells to cold stress enhanced tolerance to subsequent oxidative stress induced by menadione. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Cold Stress

Science.gov (United States)

... Publications and Products Programs Contact NIOSH NIOSH COLD STRESS Recommend on Facebook Tweet Share Compartir Workers who ... cold environments may be at risk of cold stress. Extreme cold weather is a dangerous situation that ...

Recent development of levitation melting equipment; Fuyo yokai sochi (CCLM) no shinten

Energy Technology Data Exchange (ETDEWEB)

Tadano, H.; Kainuma, K. [Fuji Electric Furnace Co. Ltd., Mie (Japan)

1998-05-10

Fuji Electric Co., Ltd., is advancing its research and development efforts for cold crucible levitation melting (CCLM) equipment in which metal is caused to be levitated in the air and is melted. Such a unit consists of a water-cooled copper crucible, a water-cooled coil installed to surround the crucible, and a high-frequency power source. Eddy currents are induced in the crucible and metal upon application of a high-frequency current to the coil, and electromagnetic repulsion is generated between the eddy currents. When the force of repulsion is greater than the force of gravity acting on the metal, the metal leaves the crucible to be levitated in the air. At the same time, the metal is heated by the Joule heat produced by the eddy currents, and is melted. So far, for the stabilized levitation melting of a kilogram-level amount of metal, a double power source excitation system has been adopted and the crucible bottom configuration has been optimized. Also, non-contact tapping of molten metal from the bottom and increase of the molten metal amount to the 50 kilogram level have been achieved, these for the industrialization of the technology. Already available on the market are equipment for large-capacity CCLM, continuous casting CCLM, and the high-vacuum CCLM. 5 refs., 13 figs., 3 tabs.

Ethylene and cold participate in the regulation of LeCBF1 gene expression in postharvest tomato fruits.

Science.gov (United States)

Zhao, Danying; Shen, Lin; Fan, Bei; Yu, Mengmeng; Zheng, Yang; Lv, Shengnan; Sheng, Jiping

2009-10-20

C-repeat/dehydration-responsive element binding factor (CBF) is a transcription factor regulating cold response in plants, of which little is known in fruits. We showed a double-peak expression pattern of Lycopersicon esculentum putative transcriptional activator CBF1 (LeCBF1) in mature green fruit. The peaks appeared at 2 and 16 h after subjection to cold storage (2 degrees C). The second peak was coincident with, and thus caused by a peak in endogenous ethylene production. We showed that LeCBF1 expression was regulated by exogenous ethylene and 1-methylcyclopropene, and was not expressed without cold induction. LeCBF1 expression was different in the five maturation stages of fruits, but expression peaked at 2 h at all stages.

Commissioning Tests of the Ulchin LLW Vitrification Facility In Korea

International Nuclear Information System (INIS)

Kyung-Hwa, Yang; Sang-Woon, Shin; Chan-Kook, Moon

2009-01-01

Since 1994, Korea Hydro and Nuclear Power Co., Ltd. (KHNP) has, together with SGN in France and Hyundai ROTEM, investigated and developed a vitrification process using a Cold Crucible Induction Melter (CCIM) to treat low-and intermediate-level radioactive waste. A commercialization project was launched in 2002 as a governmental nuclear power technology development project. The installation of the first commercial plant, Ulchin Vitrification Facility (UVF), was completed in 2007 inside Ulchin nuclear power plants no. 5 and 6. Combustible dry active waste and low-level ion exchange resin will be treated in the UVF. The UVF has a waste feeding capacity of 20 kg/h and consists of waste pretreatment and feeding systems, a cold crucible induction melter (CCIM) system, an off-gas treatment system, a dust recycling system, as well as other systems. In order to assure that systems and equipments meet their design objectives and that the UVF complies with applicable regulations, equipment tests, system functional tests and inactive performance tests were conducted. Furthermore, a long-term inactive test was carried out for 202 hours to evaluate the overall performance and stability of the facility. During the test, about 1,700 kg of surrogate waste was vitrified and 302 kg of waste glass was poured into a glass mould. As the gaseous emission from the UVF was one of the key issues for the operational license and public acceptance, 25 hazardous gases and dusts were analyzed. The compressive strength of the waste glasses was also measured. Results showed that effluent concentrations of the off-gases and the quality of the waste glass met the regulatory limits with sufficient margins. Operation procedures of the UVF were revised based on experiences gained from the tests. By demonstrating satisfactory performance of the UVF, KHNP acquired an operational license in October, 2008 as an amendment to the operational license of the Ulchin NPPs. We are planning to conduct a simulated

Characterization of cold sensitivity and thermal preference using an operant orofacial assay

Directory of Open Access Journals (Sweden)

Caudle Robert M

2006-12-01

Full Text Available Abstract Background A hallmark of many orofacial pain disorders is cold sensitivity, but relative to heat-related pain, mechanisms of cold perception and the development of cold allodynia are not clearly understood. Molecular mediators of cold sensation such as TRPM8 have been recently identified and characterized using in vitro studies. In this study we characterized operant behavior with respect to individually presented cold stimuli (24, 10, 2, and -4°C and in a thermal preference task where rats chose between -4 and 48°C stimulation. We also evaluated the effects of menthol, a TRPM8 agonist, on operant responses to cold stimulation (24, 10, and -4°C. Male and female rats were trained to drink sweetened milk while pressing their shaved faces against a thermode. This presents a conflict paradigm between milk reward and thermal stimulation. Results We demonstrated that the cold stimulus response function was modest compared to heat. There was a significant effect of temperature on facial (stimulus contacts, the ratio of licking contacts to stimulus contacts, and the stimulus duration/contact ratio. Males and females differed only in their facial contacts at 10°C. In the preference task, males preferred 48°C to -4°C, despite the fact that 48°C and -4°C were equally painful as based on their reward/stimulus and duration/contact ratios. We were able to induce hypersensitivity to cold using menthol at 10°C, but not at 24 or -4°C. Conclusion Our results indicate a strong role for an affective component in processing of cold stimuli, more so than for heat, which is in concordance with human psychophysical findings. The induction of allodynia with menthol provides a model for cold allodynia. This study provides the basis for future studies involving orofacial pain and analgesics, and is translatable to the human experience.

Acute Anxiety Predicts Components of the Cold Shock Response on Cold Water Immersion: Toward an Integrated Psychophysiological Model of Acute Cold Water Survival

Science.gov (United States)

Barwood, Martin J.; Corbett, Jo; Massey, Heather; McMorris, Terry; Tipton, Mike; Wagstaff, Christopher R. D.

2018-01-01

Introduction: Drowning is a leading cause of accidental death. In cold-water, sudden skin cooling triggers the life-threatening cold shock response (CSR). The CSR comprises tachycardia, peripheral vasoconstriction, hypertension, inspiratory gasp, and hyperventilation with the hyperventilatory component inducing hypocapnia and increasing risk of aspirating water to the lungs. Some CSR components can be reduced by habituation (i.e., reduced response to stimulus of same magnitude) induced by 3–5 short cold-water immersions (CWI). However, high levels of acute anxiety, a plausible emotion on CWI: magnifies the CSR in unhabituated participants, reverses habituated components of the CSR and prevents/delays habituation when high levels of anxiety are experienced concurrent to immersions suggesting anxiety is integral to the CSR. Purpose: To examine the predictive relationship that prior ratings of acute anxiety have with the CSR. Secondly, to examine whether anxiety ratings correlated with components of the CSR during immersion before and after induction of habituation. Methods: Forty-eight unhabituated participants completed one (CON1) 7-min immersion in to cold water (15°C). Of that cohort, twenty-five completed four further CWIs that would ordinarily induce CSR habituation. They then completed two counter-balanced immersions where anxiety levels were increased (CWI-ANX) or were not manipulated (CON2). Acute anxiety and the cardiorespiratory responses (cardiac frequency [fc], respiratory frequency [fR], tidal volume [VT], minute ventilation [E]) were measured. Multiple regression was used to identify components of the CSR from the most life-threatening period of immersion (1st minute) predicted by the anxiety rating prior to immersion. Relationships between anxiety rating and CSR components during immersion were assessed by correlation. Results: Anxiety rating predicted the fc component of the CSR in unhabituated participants (CON1; p anxiety rating predicted the f

Acute Anxiety Predicts Components of the Cold Shock Response on Cold Water Immersion: Toward an Integrated Psychophysiological Model of Acute Cold Water Survival.

Science.gov (United States)

Barwood, Martin J; Corbett, Jo; Massey, Heather; McMorris, Terry; Tipton, Mike; Wagstaff, Christopher R D

2018-01-01

Introduction: Drowning is a leading cause of accidental death. In cold-water, sudden skin cooling triggers the life-threatening cold shock response (CSR). The CSR comprises tachycardia, peripheral vasoconstriction, hypertension, inspiratory gasp, and hyperventilation with the hyperventilatory component inducing hypocapnia and increasing risk of aspirating water to the lungs. Some CSR components can be reduced by habituation (i.e., reduced response to stimulus of same magnitude) induced by 3-5 short cold-water immersions (CWI). However, high levels of acute anxiety, a plausible emotion on CWI: magnifies the CSR in unhabituated participants, reverses habituated components of the CSR and prevents/delays habituation when high levels of anxiety are experienced concurrent to immersions suggesting anxiety is integral to the CSR. Purpose: To examine the predictive relationship that prior ratings of acute anxiety have with the CSR. Secondly, to examine whether anxiety ratings correlated with components of the CSR during immersion before and after induction of habituation. Methods: Forty-eight unhabituated participants completed one (CON1) 7-min immersion in to cold water (15°C). Of that cohort, twenty-five completed four further CWIs that would ordinarily induce CSR habituation. They then completed two counter-balanced immersions where anxiety levels were increased (CWI-ANX) or were not manipulated (CON2). Acute anxiety and the cardiorespiratory responses (cardiac frequency [ f c ], respiratory frequency [ f R ], tidal volume [ V T ], minute ventilation [ E ]) were measured. Multiple regression was used to identify components of the CSR from the most life-threatening period of immersion (1 st minute) predicted by the anxiety rating prior to immersion. Relationships between anxiety rating and CSR components during immersion were assessed by correlation. Results: Anxiety rating predicted the f c component of the CSR in unhabituated participants (CON1; p CSR when anxiety

Influence of corium oxidation on fission product release from molten pool

Energy Technology Data Exchange (ETDEWEB)

Bechta, S.V., E-mail: bechta@sbor.spb.s [Alexandrov Scientific-Research Institute of Technology (NITI), Sosnovy Bor (Russian Federation); Krushinov, E.V.; Vitol, S.A.; Khabensky, V.B.; Kotova, S.Yu.; Sulatsky, A.A. [Alexandrov Scientific-Research Institute of Technology (NITI), Sosnovy Bor (Russian Federation); Gusarov, V.V.; Almyashev, V.I. [Grebenschikov Institute of Silicate Chemistry of the Russian Academy of Sciences (ISC RAS), St. Petersburg (Russian Federation); Ducros, G.; Journeau, C. [CEA, DEN, Cadarache, F-13108 St. Paul lez Durance (France); Bottomley, D. [Joint Research Centre Institut fuer Transurane (ITU), Karlsruhe (Germany); Clement, B. [Institut de Radioprotection et Surete Nucleaire (IRSN), St. Paul lez Durance (France); Herranz, L. [CIEMAT, Madrid (Spain); Guentay, S. [PSI, Wuerenlingen (Switzerland); Trambauer, K. [GRS, Muenchen (Germany); Auvinen, A. [VTT, Espoo (Finland); Bezlepkin, V.V. [SPbAEP, St. Petersburg (Russian Federation)

2010-05-15

Qualitative and quantitative determination of the release of low-volatile fission products and core materials from molten oxidic corium was investigated in the EVAN project under the auspices of ISTC. The experiments carried out in a cold crucible with induction heating and RASPLAV test facility are described. The results are discussed in terms of reactor application; in particular, pool configuration, melt oxidation kinetics, critical influence of melt surface temperature and oxidation index on the fission product release rate, aerosol particle composition and size distribution. The relevance of measured high release of Sr from the molten pool for the reactor application is highlighted. Comparisons of the experimental data with those from the COLIMA CA-U3 test and the VERCORS tests, as well as with predictions from IVTANTHERMO and GEMINI/NUCLEA codes are made. Recommendations for further investigations are proposed following the major observations and discussions.

Advanced waste form and melter development for treatment of troublesome high-level wastes

Energy Technology Data Exchange (ETDEWEB)

Marra, James [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Kim, Dong -Sang [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Maio, Vincent [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2015-09-02

A number of waste components in US defense high level radioactive wastes (HLW) have proven challenging for current Joule heated ceramic melter (JHCM) operations and have limited the ability to increase waste loadings beyond already realized levels. Many of these "troublesome" waste species cause crystallization in the glass melt that can negatively impact product quality or have a deleterious effect on melter processing. Recent efforts at US Department of Energy laboratories have focused on understanding crystallization behavior within HLW glass melts and investigating approached to mitigate the impacts of crystallization so that increases in waste loading can be realized. Advanced glass formulations have been developed to highlight the unique benefits of next-generation melter technologies such as the Cold Crucible Induction Melter (CCIM). Crystal-tolerant HLW glasses have been investigated to allow sparingly soluble components such as chromium to crystallize in the melter but pass out of the melter before accumulating.

Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure

DEFF Research Database (Denmark)

Ziętak, Marika; Kovatcheva-Datchary, Petia; Markiewicz, Lidia H

2016-01-01

Maintenance of body temperature in cold-exposed animals requires induction of thermogenesis and management of fuel. Here, we demonstrated that reducing ambient temperature attenuated diet-induced obesity (DIO), which was associated with increased iBAT thermogenesis and a plasma bile acid profile...... similar to that of germ-free mice. We observed a marked shift in the microbiome composition at the phylum and family levels within 1 day of acute cold exposure and after 4 weeks at 12°C. Gut microbiota was characterized by increased levels of Adlercreutzia, Mogibacteriaceae, Ruminococcaceae......, and Desulfovibrio and reduced levels of Bacilli, Erysipelotrichaceae, and the genus rc4-4. These genera have been associated with leanness and obesity, respectively. Germ-free mice fed a high-fat diet at room temperature gained less adiposity and improved glucose tolerance when transplanted with caecal microbiota...

Cold injuries.

Science.gov (United States)

Kruse, R J

1995-01-01

There are two categories of cold injury. The first is hypothermia, which is a systemic injury to cold, and the second is frostbite, which is a local injury. Throughout history, entire armies, from George Washington to the Germans on the Russian Front in World War II, have fallen prey to prolonged cold exposure. Cold injury is common and can occur in all seasons if ambient temperature is lower than the core body temperature. In the 1985 Boston Marathon, even though it was 76 degrees and sunny, there were 75 runners treated for hypothermia. In general, humans adapt poorly to cold exposure. Children are at particular risk because of their relatively greater surface area/body mass ratio, causing them to cool even more rapidly than adults. Because of this, the human's best defense against cold injury is to limit his/her exposure to cold and to dress appropriately. If cold injury has occurred and is mild, often simple passive rewarming such as dry blankets and a warm room are sufficient treatment.

Nondestructive characterization of recovery and recrystallization in cold rolled low carbon steel by magnetic hysteresis loops

International Nuclear Information System (INIS)

Martinez-de-Guerenu, A.; Gurruchaga, K.; Arizti, F.

2007-01-01

How structure sensitive parameters derived from hysteresis loops can provide nondestructive information about the evolution of the microstructure of cold rolled low carbon steel as a result of recovery and recrystallization processes during the annealing is shown. The coercive field, remanent induction and hysteresis losses can be used to monitor the decrease in the dislocation density during recovery. These parameters are also influenced by the average grain refinement that takes place during recrystallization, which compensates the variation produced by the annihilation of dislocations during recrystallization. The maximum of the induction and of the relative differential permeability are shown to be very sensitive to the onset and to the monitoring of the recrystallization, respectively. The correlations between coercive field and remanent induction and hysteresis losses can also be used to distinguish between recovery and recrystallization

Machinability of hypereutectic cast Al–Si alloys processed by SSM ...

Indian Academy of Sciences (India)

P K Sood

Changing the shape of intermetallic phases from plate type to Chinese script will ... carry out machining, diamond tools of complex geometry are used due to their ... minium in a graphite crucible using an induction furnace. To avoid oxidation ...

Cold plate

Energy Technology Data Exchange (ETDEWEB)

Marroquin, Christopher M.; O' Connell, Kevin M.; Schultz, Mark D.; Tian, Shurong

2018-02-13

A cold plate, an electronic assembly including a cold plate, and a method for forming a cold plate are provided. The cold plate includes an interface plate and an opposing plate that form a plenum. The cold plate includes a plurality of active areas arranged for alignment over respective heat generating portions of an electronic assembly, and non-active areas between the active areas. A cooling fluid flows through the plenum. The plenum, at the non-active areas, has a reduced width and/or reduced height relative to the plenum at the active areas. The reduced width and/or height of the plenum, and exterior dimensions of cold plate, at the non-active areas allow the non-active areas to flex to accommodate surface variations of the electronics assembly. The reduced width and/or height non-active areas can be specifically shaped to fit between physical features of the electronics assembly.

INTERACTION STUDIES OF CERAMIC VACUUM PLASMA SPRAYING FOR THE MELTING CRUCIBLE MATERIALS

Directory of Open Access Journals (Sweden)

JONG HWAN KIM

2013-10-01

Full Text Available Candidate coating materials for re-usable metallic nuclear fuel crucibles, TaC, TiC, ZrC, ZrO2, and Y2O3, were plasma-sprayed onto a niobium substrate. The microstructure of the plasma-sprayed coatings and thermal cycling behavior were characterized, and U-Zr melt interaction studies were carried out. The TaC and Y2O3 coating layers had a uniform thickness, and high density with only a few small closed pores showing good consolidation, while the ZrC, TiC, and ZrO2 coatings were not well consolidated with a considerable amount of porosity. Thermal cycling tests showed that the adhesion of the TiC, ZrC, and ZrO2 coating layers with niobium was relatively weak compared to the TaC and Y2O3 coatings. The TaC and Y2O3 coatings had better cycling characteristics with no interconnected cracks. In the interaction studies, ZrC and ZrO2 coated rods showed significant degradations after exposure to U-10 wt.% Zr melt at 1600°C for 15 min., but TaC, TiC, and Y2O3 coatings showed good compatibility with U-Zr melt.

Interaction with diurnal and circadian regulation results in dynamic metabolic and transcriptional changes during cold acclimation in Arabidopsis.

Directory of Open Access Journals (Sweden)

Carmen Espinoza

Full Text Available In plants, there is a large overlap between cold and circadian regulated genes and in Arabidopsis, we have shown that cold (4°C affects the expression of clock oscillator genes. However, a broader insight into the significance of diurnal and/or circadian regulation of cold responses, particularly for metabolic pathways, and their physiological relevance is lacking. Here, we performed an integrated analysis of transcripts and primary metabolites using microarrays and gas chromatography-mass spectrometry. As expected, expression of diurnally regulated genes was massively affected during cold acclimation. Our data indicate that disruption of clock function at the transcriptional level extends to metabolic regulation. About 80% of metabolites that showed diurnal cycles maintained these during cold treatment. In particular, maltose content showed a massive night-specific increase in the cold. However, under free-running conditions, maltose was the only metabolite that maintained any oscillations in the cold. Furthermore, although starch accumulates during cold acclimation we show it is still degraded at night, indicating significance beyond the previously demonstrated role of maltose and starch breakdown in the initial phase of cold acclimation. Levels of some conventional cold induced metabolites, such as γ-aminobutyric acid, galactinol, raffinose and putrescine, exhibited diurnal and circadian oscillations and transcripts encoding their biosynthetic enzymes often also cycled and preceded their cold-induction, in agreement with transcriptional regulation. However, the accumulation of other cold-responsive metabolites, for instance homoserine, methionine and maltose, did not have consistent transcriptional regulation, implying that metabolic reconfiguration involves complex transcriptional and post-transcriptional mechanisms. These data demonstrate the importance of understanding cold acclimation in the correct day-night context, and are further

Investigation of processing effects on the corrosion resistance of Ti20Mo alloy in saline solutions

International Nuclear Information System (INIS)

Bolat, G.; Izquierdo, J.; Gloriant, T.; Chelariu, R.; Mareci, D.; Souto, R.M.

2015-01-01

Graphical abstract: - Highlights: • Alloy fabrication method affects both surface finish and corrosion resistance. • More porous surface finish and higher wettability produced by powder sintering. • Passive layer formed on sintered alloy breaks down in saline solution. • Increase in surface porosity facilitated electron transfer through the oxide film. • More corrosion resistant alloy produced by cold crucible levitation melting. - Abstract: The electrochemical properties of Ti20Mo alloys prepared using different fabrication procedures, namely cold crucible levitation melting (CCLM) and powder sintering, were investigated using linear potentiodynamic polarization and EIS measurements. The surface condition was established using AFM, with the observation of a more porous surface finish in the case of powder sintering. A major effect of surface conditioning on the corrosion resistance of Ti20Mo alloys was observed, where the compact finish exhibits a superior corrosion resistance in chloride-containing saline solutions. Less insulating surfaces towards electron exchange resulted for the more porous finish as revealed by scanning electrochemical microscopy (SECM)

Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype

Czech Academy of Sciences Publication Activity Database

Flachs, Pavel; Adamcová, Kateřina; Zouhar, Petr; Marques, C.; Janovská, Petra; Viegas, I.; Jones, J. G.; Bardová, Kristina; Svobodová, Michaela; Hansíková, Jana; Kuda, Ondřej; Rossmeisl, Martin; Liisberg, U.; Borkowska, A. G.; Kristiansen, K.; Madsen, L.; Kopecký, Jan

2017-01-01

Roč. 41, č. 3 (2017), s. 372-380 ISSN 0307-0565 R&D Projects: GA ČR(CZ) GA13-00871S; GA MŠk(CZ) 7E12073 Institutional support: RVO:67985823 Keywords : cold exposure * epididymal adipose tissue * futile substrate cycling * lipogenesis Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition OBOR OECD: Endocrinology and metabolism (including diabetes, hormones) Impact factor: 5.487, year: 2016

Conceptualizing Cold Disasters

DEFF Research Database (Denmark)

Lauta, Kristian Cedervall; Dahlberg, Rasmus; Vendelø, Morten Thanning

2017-01-01

In the present article, we explore in more depth the particular circumstances and characteristics of governing what we call ‘cold disasters’, and thereby, the paper sets out to investigate how disasters in cold contexts distinguish themselves from other disasters, and what the implications hereof...... are for the conceptualization and governance of cold disasters. Hence, the paper can also be viewed as a response to Alexander’s (2012a) recent call for new theory in the field of disaster risk reduction. The article is structured in four overall parts. The first part, Cold Context, provides an overview of the specific...... conditions in a cold context, exemplified by the Arctic, and zooms in on Greenland to provide more specific background for the paper. The second part, Disasters in Cold Contexts, discusses “cold disasters” in relation to disaster theory, in order to, elucidate how cold disasters challenge existing...

Chemical decontamination and melt densification

International Nuclear Information System (INIS)

Dillon, R.L.; Griggs, B.; Kemper, R.S.; Nelson, R.G.

1976-01-01

Preliminary studies on the chemical decontamination and densification of Zircaloy, stainless steel, and Inconel undissolved residues remaining after dissolution of the UO 2 --PuO 2 spent fuel material from sheared fuel bundles are reported. The studies were made on cold or very small samples to demonstrate the feasibility of the processes developed before proceeding to hot cell demonstrations with kg level of the sources. A promising aqueous decontamination method for Zr alloy cladding was developed in which oxidized surfaces are conditioned with HF prior to leaching with ammonium oxalate, ammonium citrate, ammonium fluoride, and hydrogen peroxide. Feasibility of molten salt decontamination of oxidized Zircaloy was demonstrated. A low melting alloy of Zircaloy, stainless steel, and Inconel was obtained in induction heated graphite crucibles. Segregated Zircaloy cladding sections were directly melted by the inductoslag process to yield a metal ingot suitable for storage. Both Zircaloy and Zircaloy--stainless steel--Inconel alloys proved to be highly satisfactory getters and sinks for recovered tritium

Mutation induction for improving of tangerine in Iran

Energy Technology Data Exchange (ETDEWEB)

Majd, F.; Jahangirzadeh, E.; Vedadi, S.; Tafti, M. Naseri; Rastegari, J. [Nuclear Research Center for Agriculture and Medicine, Karaj (Iran, Islamic Republic of)

2009-05-15

Genetic variation is an essential component of crop breeding. Induced mutations are highly effective in enhancing natural variability of genetic resources, and have been instrumental in developing improved cultivars of crops including fruits crops. Recent advances in biotechnological techniques have shown a great potential as efficient methodologies for vegetative micropropagation, screening techniques and genetic characterization including mutation induction. On this basis, a local, well- adapted and widely-consumed Clementine cultivar was selected for introduction into a mutation induction programme in order to reduce the excessive seeds in the fruits. A physical mutagen (γ-ray) was applied at doses of 35, 40 and 45 Gy on selected seedling apical buds. Irradiated buds were grafted onto sour orange root stocks (M{sub 1}V{sub 1}) and chimeras disassociated by further vegetative propagation. Finally M{sub 1}V{sub 3} plants were transferred to the field and after the production of fruits, selection for the desired fruit types was undertaken. The results showed that the radiation treatment was able to produce mutant genotypes with seedless fruits, early and late ripening and cold tolerance. (author)

Cold urticaria. Dissociation of cold-evoked histamine release and urticara following cold challenge.

Science.gov (United States)

Keahey, T M; Greaves, M W

1980-02-01

Nine patients with acquired cold urticaria were studied to assess the effects of beta-adrenergic agents, xanthines, and corticosteroids on cold-evoked histamine release from skin in vivo. The patients, in all of whom an immediate urticarial response developed after cooling of the forearm, demonstrated release of histamine into the venous blood draining that forearm. Following treatment with aminophylline and albuterol in combination or prednisone alone, suppression of histamine release occurred in all but one patient. In some patients, this was accompanied by a subjective diminution in pruritus or buring, but there was no significant improvement in the ensuing edema or erythema. In one patient, total suppression of histamine release was achieved without any effect on whealing and erythema in response to cold challenge. Our results suggest that histamine is not central to the pathogenesis of vascular changes in acquired cold urticaria.

Fructan metabolism and changes in fructan composition during cold acclimation in perennial ryegrass

DEFF Research Database (Denmark)

Abeynayake, Shamila; Etzerodt, Thomas; Jonavičienė, Kristina

2015-01-01

. The ecotype ‘Falster’, adapted to cold climates, increased total fructan content and produced more fructans (DP˃7) in the roots than the variety ‘Veyo’, adapted to warmer climates suggesting that accumulation of fructans in roots, especially the high-DP fructans as an adaptive trait for plant recovery after......Perennial ryegrass (Lolium perenne L.) produces high levels of fructans as a mixture of oligomers with different degrees of polymerization (DP). The present study describes the analysis of the compositional changes in the full spectrum of fructan oligomers, fructan distribution between above ground...... biomass (top) and the roots, and the transcription of candidate genes involved in fructan metabolism during cold acclimation in perennial ryegrass variety ‘Veyo’ and ecotype ‘Falster’ from distinct geographical origins. We observed changes in fructan composition and induction of low-DP fructans...

Relationships of self-identified cold tolerance and cold-induced vasodilatation in the finger

Science.gov (United States)

Park, Joonhee; Lee, Joo-Young

2016-04-01

This study was conducted to investigate relationships of self-identified cold tolerance and cold-induced vasodilatation (CIVD) in the finger. Nine males and 34 females participated in the following 2 tests: a CIVD test and a self-reported survey. The CIVD test was conducted 30-min cold-water immersion (3.8 ± 0.3 °C) of the middle finger at an air temperature of 27.9 ± 0.1 °C. The self-reported questionnaire consisted of 28 questions about whole and local body cold and heat tolerances. By a cluster analysis on the survey results, the participants were divided into two groups: high self-identified cold tolerance (HSCT, n = 25) and low self-identified cold tolerance (LSCT, n = 18). LSCT had lower self-identified cold tolerance ( P cold or heat tolerance had relationships with cold tolerance index, T max, and amplitude ( P cold tolerance classified through a standardized survey could be a good index to predict physiological cold tolerance.

Burning Cold: Involvement of TRPA1 in Noxious Cold Sensation

OpenAIRE

Kwan, Kelvin Y.; Corey, David P.

2009-01-01

Soon after its discovery ten years ago, the ion channel TRPA1 was proposed as a sensor of noxious cold. Evidence for its activation by painfully cold temperatures (below ~15° C) has been mixed, however. Some groups found that cold elicits a nonselective conductance in cells expressing TRPA1; others found no activation, or argued that activation is an indirect effect of elevated \\(Ca^{ 2+}\\) . Sensory cells from the trigeminal and dorsal root ganglia that are activated by cold were sometimes c...

Induction of cold hardiness in an invasive herbivore: The case of hemlock woolly adelgid (Hemiptera: Adelgidae)

Science.gov (United States)

Joseph S. Elkinton; Jeffrey A. Lombardo; Artemis D. Roehrig; Thomas J. McAvoy; Albert Mayfield; Mark Whitmore

2017-01-01

As a measure of cold hardiness, we tested the supercooling points or freezing temperatures of individual hemlock woolly adelgids (Adelges tsugae Annand) collected from 15 locations across the north to south range of the adelgid in eastern North America at different times during two winters. Adelgids from the northern interior locations with USDA hardiness zones of 5B–...

Status of MUSIC, the MUltiwavelength Sub/millimeter Inductance Camera

Science.gov (United States)

Golwala, Sunil R.; Bockstiegel, Clint; Brugger, Spencer; Czakon, Nicole G.; Day, Peter K.; Downes, Thomas P.; Duan, Ran; Gao, Jiansong; Gill, Amandeep K.; Glenn, Jason; Hollister, Matthew I.; LeDuc, Henry G.; Maloney, Philip R.; Mazin, Benjamin A.; McHugh, Sean G.; Miller, David; Noroozian, Omid; Nguyen, Hien T.; Sayers, Jack; Schlaerth, James A.; Siegel, Seth; Vayonakis, Anastasios K.; Wilson, Philip R.; Zmuidzinas, Jonas

2012-09-01

We present the status of MUSIC, the MUltiwavelength Sub/millimeter Inductance Camera, a new instrument for the Caltech Submillimeter Observatory. MUSIC is designed to have a 14', diffraction-limited field-of-view instrumented with 2304 detectors in 576 spatial pixels and four spectral bands at 0.87, 1.04, 1.33, and 1.98 mm. MUSIC will be used to study dusty star-forming galaxies, galaxy clusters via the Sunyaev-Zeldovich effect, and star formation in our own and nearby galaxies. MUSIC uses broadband superconducting phased-array slot-dipole antennas to form beams, lumpedelement on-chip bandpass filters to define spectral bands, and microwave kinetic inductance detectors to sense incoming light. The focal plane is fabricated in 8 tiles consisting of 72 spatial pixels each. It is coupled to the telescope via an ambient-temperature ellipsoidal mirror and a cold reimaging lens. A cold Lyot stop sits at the image of the primary mirror formed by the ellipsoidal mirror. Dielectric and metal-mesh filters are used to block thermal infrared and out-ofband radiation. The instrument uses a pulse tube cooler and 3He/ 3He/4He closed-cycle cooler to cool the focal plane to below 250 mK. A multilayer shield attenuates Earth's magnetic field. Each focal plane tile is read out by a single pair of coaxes and a HEMT amplifier. The readout system consists of 16 copies of custom-designed ADC/DAC and IF boards coupled to the CASPER ROACH platform. We focus on recent updates on the instrument design and results from the commissioning of the full camera in 2012.

Stereomicroscopic imaging technique for the quantification of cold flow in drug-in-adhesive type of transdermal drug delivery systems.

Science.gov (United States)

Krishnaiah, Yellela S R; Katragadda, Usha; Khan, Mansoor A

2014-05-01

Cold flow is a phenomenon occurring in drug-in-adhesive type of transdermal drug delivery systems (DIA-TDDS) because of the migration of DIA coat beyond the edge. Excessive cold flow can affect their therapeutic effectiveness, make removal of DIA-TDDS difficult from the pouch, and potentially decrease available dose if any drug remains adhered to pouch. There are no compendial or noncompendial methods available for quantification of this critical quality attribute. The objective was to develop a method for quantification of cold flow using stereomicroscopic imaging technique. Cold flow was induced by applying 1 kg force on punched-out samples of marketed estradiol DIA-TDDS (model product) stored at 25°C, 32°C, and 40°C/60% relative humidity (RH) for 1, 2, or 3 days. At the end of testing period, dimensional change in the area of DIA-TDDS samples was measured using image analysis software, and expressed as percent of cold flow. The percent of cold flow significantly decreased (p < 0.001) with increase in size of punched-out DIA-TDDS samples and increased (p < 0.001) with increase in cold flow induction temperature and time. This first ever report suggests that dimensional change in the area of punched-out samples stored at 32°C/60%RH for 2 days applied with 1 kg force could be used for quantification of cold flow in DIA-TDDS. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

Cold-Hearted or Cool-Headed: Physical Coldness Promotes Utilitarian Moral Judgment

Directory of Open Access Journals (Sweden)

Hiroko eNakamura

2014-10-01

Full Text Available In the current study, we examine the effect of physical coldness on personal moral dilemma judgment. Previous studies have indicated that utilitarian moral judgment—sacrificing a few people to achieve the greater good for others—was facilitated when: (1 participants suppressed an initial emotional response and deliberately thought about the utility of outcomes; (2 participants had a high-level construal mindset and focused on abstract goals (e.g., save many; or (3 there was a decreasing emotional response to sacrificing a few. In two experiments, we exposed participants to extreme cold or typical room temperature and then asked them to make personal moral dilemma judgments. The results of Experiment 1 indicated that coldness prompted utilitarian judgment, but the effect of coldness was independent from deliberate thought or abstract high-level construal mindset. As Experiment 2 revealed, coldness facilitated utilitarian judgment via reduced empathic feelings. Therefore, physical coldness did not affect the cool-headed deliberate process or the abstract high-level construal mindset. Rather, coldness biased people toward being cold-hearted, reduced empathetic concern about a sacrificed victim, and facilitated utilitarian moral judgments.

Two key temporally distinguishable molecular and cellular components of white adipose tissue browning during cold acclimation.

Science.gov (United States)

Jankovic, Aleksandra; Golic, Igor; Markelic, Milica; Stancic, Ana; Otasevic, Vesna; Buzadzic, Biljana; Korac, Aleksandra; Korac, Bato

2015-08-01

White to brown adipose tissue conversion and thermogenesis can be ignited by different conditions or agents and its sustainability over the long term is still unclear. Browning of rat retroperitoneal white adipose tissue (rpWAT) during cold acclimation involves two temporally apparent components: (1) a predominant non-selective browning of most adipocytes and an initial sharp but transient induction of uncoupling protein 1, peroxisome proliferator-activated receptor (PPAR) coactivator-1α, PPARγ and PPARα expression, and (2) the subsistence of relatively few thermogenically competent adipocytes after 45 days of cold acclimation. The different behaviours of two rpWAT beige/brown adipocyte subsets control temporal aspects of the browning process, and thus regulation of both components may influence body weight and the potential successfulness of anti-obesity therapies. Conversion of white into brown adipose tissue may have important implications in obesity resistance and treatment. Several browning agents or conditions ignite thermogenesis in white adipose tissue (WAT). To reveal the capacity of WAT to function in a brownish/burning mode over the long term, we investigated the progression of the rat retroperitoneal WAT (rpWAT) browning during 45 days of cold acclimation. During the early stages of cold acclimation, the majority of rpWAT adipocytes underwent multilocularization and thermogenic-profile induction, as demonstrated by the presence of a multitude of uncoupling protein 1 (UCP1)-immunopositive paucilocular adipocytes containing peroxisome proliferator-activated receptor (PPAR) coactivator-1α (PGC-1α) and PR domain-containing 16 (PRDM16) in their nuclei. After 45 days, all adipocytes remained PRDM16 immunopositive, but only a few multilocular adipocytes rich in mitochondria remained UCP1/PGC-1α immunopositive. Molecular evidence showed that thermogenic recruitment of rpWAT occurred following cold exposure, but returned to starting levels after cold

Genotype-dependent Burst of Transposable Element Expression in Crowns of Hexaploid Wheat (Triticum aestivum L. during Cold Acclimation

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Debbie Laudencia-Chingcuanco

2012-01-01

Full Text Available The expression of 1,613 transposable elements (TEs represented in the Affymetrix Wheat Genome Chip was examined during cold treatment in crowns of four hexaploid wheat genotypes that vary in tolerance to cold and in flowering time. The TE expression profiles showed a constant level of expression throughout the experiment in three of the genotypes. In winter Norstar, the most cold-hardy of the four genotypes, a subset of the TEs showed a burst of expression after vernalization saturation was achieved. About 47% of the TEs were expressed, and both Class I (retrotransposons and Class II (DNA transposons types were well represented. Gypsy and Copia were the most represented among the retrotransposons while CACTA and Mariner were the most represented DNA transposons. The data suggests that the Vrn-A1 region plays a role in the stage-specific induction of TE expression in this genotype.

Alteration of gene expression during the induction of freezing tolerance in Brassica napus suspension cultures

International Nuclear Information System (INIS)

Johnson-Flanagan, A.M.; Singh, J.

1987-01-01

Brassica napus suspension-cultured cells can be hardened to a lethal temperature for 50% of the sample of -20 0 C in eight days at room temperature with abscisic acid. During the induction of freezing tolerance, changes were observed in the electrophoretic pattern of [ 35 S]methionine labeled polypeptides. In hardening cells, a 20 kilodalton polypeptide was induced on day 2 and its level increased during hardening. The induction of freezing tolerance with nonmaximal hardening regimens also resulted in increases in the 20 kilodalton polypeptide. The 20 kilodalton polypeptide was associated with a membrane fraction enriched in endoplasmic reticulum and was resolved as a single spot by two-dimensional electrophoresis. In vitro translation of mRNA indicate alteration of gene expression during abscisic acid induction of freezing tolerance. The new mRNA encodes a 20 kilodalton polypeptide associated with increased freezing tolerance induced by either abscisic acid or high sucrose. A 20 kilodalton polypeptide was also translated by mRNA isolated from cold-hardened B. napus plants

Analysis of Stress-Responsive Gene Expression in Cultivated and Weedy Rice Differing in Cold Stress Tolerance.

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Caroline Borges Bevilacqua

Full Text Available Rice (Oryza sativa L. cultivars show impairment of growth in response to environmental stresses such as cold at the early seedling stage. Locally adapted weedy rice is able to survive under adverse environmental conditions, and can emerge in fields from greater soil depth. Cold-tolerant weedy rice can be a good genetic source for developing cold-tolerant, weed-competitive rice cultivars. An in-depth analysis is presented here of diverse indica and japonica rice genotypes, mostly weedy rice, for cold stress response to provide an understanding of different stress adaptive mechanisms towards improvement of the rice crop performance in the field. We have tested a collection of weedy rice genotypes to: 1 classify the subspecies (ssp. grouping (japonica or indica of 21 accessions; 2 evaluate their sensitivity to cold stress; and 3 analyze the expression of stress-responsive genes under cold stress and a combination of cold and depth stress. Seeds were germinated at 25°C at 1.5- and 10-cm sowing depth for 10d. Seedlings were then exposed to cold stress at 10°C for 6, 24 and 96h, and the expression of cold-, anoxia-, and submergence-inducible genes was analyzed. Control plants were seeded at 1.5cm depth and kept at 25°C. The analysis revealed that cold stress signaling in indica genotypes is more complex than that of japonica as it operates via both the CBF-dependent and CBF-independent pathways, implicated through induction of transcription factors including OsNAC2, OsMYB46 and OsF-BOX28. When plants were exposed to cold + sowing depth stress, a complex signaling network was induced that involved cross talk between stresses mediated by CBF-dependent and CBF-independent pathways to circumvent the detrimental effects of stresses. The experiments revealed the importance of the CBF regulon for tolerance to both stresses in japonica and indica ssp. The mechanisms for cold tolerance differed among weedy indica genotypes and also between weedy indica and

Grooved cold moderator tests

International Nuclear Information System (INIS)

Inoue, K.; Kiyanagi, Y.; Iwasa, H.; Watanabe, N.; Ikeda, S.; Carpenter, J.M.; Ishikawa, Y.

1983-01-01

We performed some grooved cold moderator experiments for methane at 20 K by using the Hokkaido University linac to obtain information to be used in the planning of the KENS-I' project. Cold neutron gains, spatial distribution of emitted beams and time distribution of the neutrons in the grooved cold moderator were measured. Furthermore, we assessed the effects of the grooved cold moderator on the performances of the spectrometers presently installed at the KENS-I cold source. We concluded that the grooved cold moderator benefited appreciably the performances of the spectrometers

Fabrication of Al doped ZnO films using atmospheric pressure cold plasma

International Nuclear Information System (INIS)

Suzaki, Yoshifumi; Miyagawa, Hayato; Yamaguchi, Kenzo; Kim, Yoon-Kee

2012-01-01

Under atmospheric pressure, homogeneous non-equilibrium cold plasma was generated stably by high voltage pulsed power (1 kV, 20 kHz, 38 W) excitation of a mixture of He and O 2 gases produced by a dielectric barrier discharge setup. By feeding Bis (2 methoxy‐6-methyl‐3, 5-heptanedione) Zn (Zn-MOPD, C 18 H 3 O 6 Zn) and Tris (2-methoxy‐6‐methy l‐3, 5-heptanedione) Al (Al-MOPD, C 27 H 45 O 9 Al) into this plasma with He carrier gas, transparent flat Al-doped ZnO (ZnO:Al) films about 120–240 nm thick were prepared on glass substrates directly under the slit made into the cathode. Deposition rates of the films were about 20–40 nm/min. The concentration of Al was measured by inductively coupled plasma atomic emission spectroscopy. The composition ratio of Al to Zn was 7.8 mol% when the carrier He gas flow rate of Al-MOPD was 30 cm 3 . The average transmittance of all films was more than 85% in the wavelength range from 400 to 800 nm. When the composition ratio of Al/Zn was between 1.1 and 7.8 mol%, the optical band gap of the film increased from 3.28 to 3.40 eV. The resistivity of ZnO:Al film was 2.96 Ω cm at 1.3 mol% of Al/Zn. In addition, the microstructure of the films was studied by X-ray diffraction measurement and field emission scanning electron microscope observation. It was revealed that doped Al is substituted onto the Zn site of the ZnO crystalline structure in ZnO:Al films. - Highlights: ► An atmospheric pressure cold plasma generator generated stable glow discharge. ► We fabricated Al doped ZnO films on glass substrates using cold plasma. ► Al concentration measured by inductively coupled plasma atomic emission spectroscopy. ► The transmission spectrum and the resistivity of the films were measured. ► The microstructure of the films was studied.

Analysis of four dental alloys following torch/centrifugal and induction/ vacuum-pressure casting procedures.

Science.gov (United States)

Thompson, Geoffrey A; Luo, Qing; Hefti, Arthur

2013-12-01

level of castability (98.5% on average) was achieved overall. The frequency of casting failures as a function of alloy type and casting method was determined. Failure was defined as a castability index score of casting combinations were statistically significant. The results suggested that casting technique affects the castability index of alloys. Radiographic analysis detected large porosities in regions near the edge of the castability pattern and infrequently adjacent to noncast segments. All castings acquired traces of elements found in the casting crucibles. The grain size for each dental casting alloy was generally finer for specimens produced by the induction/vacuum-pressure method. The difference was substantial for JO and L. This study demonstrated a relation between casting techniques and some physical properties of metal ceramic casting alloys. Copyright © 2013 Editorial Council for the Journal of Prosthetic Dentistry. Published by Mosby, Inc. All rights reserved.

CD36 is indispensable for thermogenesis under conditions of fasting and cold stress

International Nuclear Information System (INIS)

Putri, Mirasari; Syamsunarno, Mas Rizky A.A.; Iso, Tatsuya; Yamaguchi, Aiko; Hanaoka, Hirofumi; Sunaga, Hiroaki; Koitabashi, Norimichi; Matsui, Hiroki; Yamazaki, Chiho; Kameo, Satomi; Tsushima, Yoshito

2015-01-01

Hypothermia can occur during fasting when thermoregulatory mechanisms, involving fatty acid (FA) utilization, are disturbed. CD36/FA translocase is a membrane protein which facilitates membrane transport of long-chain FA in the FA consuming heart, skeletal muscle (SkM) and adipose tissues. It also accelerates uptake of triglyceride-rich lipoprotein by brown adipose tissue (BAT) in a cold environment. In mice deficient for CD36 (CD36 −/− mice), FA uptake is markedly reduced with a compensatory increase in glucose uptake in the heart and SkM, resulting in lower levels of blood glucose especially during fasting. However, the role of CD36 in thermogenic activity during fasting remains to be determined. In fasted CD36 −/− mice, body temperature drastically decreased shortly after cold exposure. The hypothermia was accompanied by a marked reduction in blood glucose and in stores of triacylglycerols in BAT and of glycogen in glycolytic SkM. Biodistribution analysis using the FA analogue 125 I-BMIPP and the glucose analogue 18 F-FDG revealed that uptake of FA and glucose was severely impaired in BAT and glycolytic SkM in cold-exposed CD36 −/− mice. Further, induction of the genes of thermogenesis in BAT was blunted in fasted CD36 −/− mice after cold exposure. These findings strongly suggest that CD36 −/− mice exhibit pronounced hypothermia after fasting due to depletion of energy storage in BAT and glycolytic SkM and to reduced supply of energy substrates to these tissues. Our study underscores the importance of CD36 for nutrient homeostasis to survive potentially life-threatening challenges, such as cold and starvation. - Highlights: • We examined the role of CD36 in thermogenesis during cold exposure. • CD36 −/− mice exhibit rapid hypothermia after cold exposure during fasting. • Uptake of fatty acid and glucose is impaired in thermogenic tissues during fasting. • Storage of energy substrates is reduced in thermogenic tissues during

Cold acclimation increases cold tolerance independently of diapause programing in the bean bug, Riptortus pedestris.

Science.gov (United States)

Rozsypal, J; Moos, M; Goto, S G

2017-10-17

The bean bug (Riptortus pedestris) is a pest of soybeans and other legumes in Japan and other Asian countries. It enters a facultative adult diapause on exposure to short days. While photoperiodism and diapause are well understood in R. pedestris, knowledge of cold tolerance is very limited, as is information on the effect of diapause on cold tolerance. We examined the effect of photoperiod, cold acclimation, and feeding status on cold tolerance in R. pedestris. We found that cold acclimation significantly increased survival at -10°C in both long- and short-day adult R. pedestris. Since the difference in cold survival between long- and short-day cold-acclimated groups was only marginal, we conclude that entering diapause is not crucial for R. pedestris to successfully pass through cold acclimation and become cold tolerant. We observed similar effects in 5th instar nymphs, with both long- and short-day cold-acclimated groups surviving longer cold exposures compared with non-acclimated groups. Starvation, which was tested only in adult bugs, had only a negligible and negative impact on cold survival. Although cold tolerance significantly increased with cold acclimation in adult bugs, supercooling capacity unexpectedly decreased. Our results suggest that changes in supercooling capacity as well as in water content are unrelated to cold tolerance in R. pedestris. An analysis of metabolites revealed differences between the treatments, and while several metabolites markedly increased with cold acclimation, their concentrations were too low to have a significant effect on cold tolerance.

Pyrolysis and oxidative pyrolysis experiments with organization exchange resin

International Nuclear Information System (INIS)

Chun, Ung Kyung

1997-01-01

Pyrolysis may be an important pretreatment step before vitrification in a cold crucible melter (CCM). During vitrification of organic resin the carbon or other remaining residues may harm the performance of the cold crucible melter of the eventual stability of the final glass product. Hence, it is important to reduce or prevent such harmful waste from entry into the cold crucible melter. Pretreatment with pyrolysis will generally provide volume reduction resulting in less amount of solid waste that needs to be handled by the CCM; in addition, the pyrolytic processes may breakdown much of the complex organics causing release through volatilization resulting in less carbon and other harmful substances. Hence, KEPRI has undertaken studies on the pyrolysis and oxidative pyrolysis of organic ion exchange resin. Pyrolysis and oxidative pyrolysis were examined with TGA and a tube furnace. TGA results for pyrolysis with the flow of nitrogen indicate that even after pyrolyzing from room temperature to about 900 deg C, a significant mass fraction of the original cationic resin remains, approximately 46 %. The anionic resin when pyrolytically heated in a flow of nitrogen only, from room temperature to about 900 deg C, produced a final residue mass fraction of about 8 percent. Oxidation at a ratio of air to nitrogen, 1:2, reduced the cationic resin to 5.3% when heated at 5 C/min. Oxidation of anionic resin at the same ratio and same heating rate left almost no solid residue. Pyrolysis (e.g. nitrogen-only environment) in the tube furnace of larger samples relative to the TGA produced very similar results to the TGA. The differences may be attributed to the scale effects such as surface area exposure to the gas stream, temperature distributions throughout the resin, etc. (author) 7 refs., 7 figs

Pyrolysis and oxidative pyrolysis experiments with organization exchange resin

Energy Technology Data Exchange (ETDEWEB)

Chun, Ung Kyung [Korea Electric Power Research Insititute, Taejon (Korea, Republic of)

1997-12-31

Pyrolysis may be an important pretreatment step before vitrification in a cold crucible melter (CCM). During vitrification of organic resin the carbon or other remaining residues may harm the performance of the cold crucible melter of the eventual stability of the final glass product. Hence, it is important to reduce or prevent such harmful waste from entry into the cold crucible melter. Pretreatment with pyrolysis will generally provide volume reduction resulting in less amount of solid waste that needs to be handled by the CCM; in addition, the pyrolytic processes may breakdown much of the complex organics causing release through volatilization resulting in less carbon and other harmful substances. Hence, KEPRI has undertaken studies on the pyrolysis and oxidative pyrolysis of organic ion exchange resin. Pyrolysis and oxidative pyrolysis were examined with TGA and a tube furnace. TGA results for pyrolysis with the flow of nitrogen indicate that even after pyrolyzing from room temperature to about 900 deg C, a significant mass fraction of the original cationic resin remains, approximately 46 %. The anionic resin when pyrolytically heated in a flow of nitrogen only, from room temperature to about 900 deg C, produced a final residue mass fraction of about 8 percent. Oxidation at a ratio of air to nitrogen, 1:2, reduced the cationic resin to 5.3% when heated at 5 C/min. Oxidation of anionic resin at the same ratio and same heating rate left almost no solid residue. Pyrolysis (e.g. nitrogen-only environment) in the tube furnace of larger samples relative to the TGA produced very similar results to the TGA. The differences may be attributed to the scale effects such as surface area exposure to the gas stream, temperature distributions throughout the resin, etc. (author) 7 refs., 7 figs.

Reducing the radiotoxicity of PWR cladding hulls by cold-crucible melting

Energy Technology Data Exchange (ETDEWEB)

Berthier, P.; Boen, R.; Piccinato, R.; Ladirat, C.

1994-12-31

PWR cladding wastes from spent fuel reprocessing plants are highly radiotoxic due to the presence of long-lived alpha-emitting nuclides and certain beta-gamma emitters. Various options are now under consideration for disposal of such wastes. The ``Commissariat a l`Energie Atomique`` is now developing a melting process at Marcoule that promises to diminish their radiotoxicity. Work has focused on two complementary research areas: obtaining a high quality metallic containment matrix and achieving maximum decontamination by concentrating the plutonium and minor actinides together with cesium and strontium in the slag. Vitrification represents a short-term solution for the slag; from a longer-term perspective, this waste form is ideally suited for the SPIN programme. This is an indispensable step toward the possible implementation of an advanced waste management strategy involving actinide separation and transmutation to reduce the long-term nuclear waste disposal hazard. (author). 1 ref., 2 figs., 8 tabs.

Induction heating of a spherical aluminum moderator vessel for the Advanced Neutron Source (ANS)

International Nuclear Information System (INIS)

Yousuf, A.

1994-01-01

This task was to identify and design a heating system to apply 15 kW of heat to a cold source vessel to simulate the Advanced Neutron Source reactor. This research project aims at the analysis of the induction heating of a spherical aluminum moderator vessel. Computer modeling is presented for the design and analysis of the induction heating system. The objective is to apply 15 kW of heat as uniformly as possible to the outer wall of a 410 mm diameter sphere of thickness 1.5 mm. The report also aims at the analysis of a system model which is simulated using the Eddycuff electromagnetic software. The computer model is built with the finite element analysis software Patran. The induction heating system analysis shows that the predicted performance is in close agreement with the computer simulated data. Hardware constraints such as power supplies and matching load are also analyzed in terms of performance and cost. Physical modeling is also suggested, in which the coil and the workpiece are scaled down

Sll0528, a Site-2-Protease, Is Critically Involved in Cold, Salt and Hyperosmotic Stress Acclimation of Cyanobacterium Synechocystis sp. PCC 6803

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Haijin Lei

2014-12-01

Full Text Available Site-2-proteases (S2Ps mediated proteolysis of transmembrane transcriptional regulators is a conserved mechanism to regulate transmembrane signaling. The universal presence of S2P homologs in different cyanobacterial genomes suggest conserved and fundamental functions, though limited data has been available. Here we provide the first evidence that Sll0528, a site-2-protease in Synechocystis sp. PCC 6803 is crucial for salt, cold and hyperosmotic stress acclimation. Remarkable induction of sll0528 gene expression was observed under salt, cold and hyperosmotic stress, much higher than induction of the other three S2Ps. Knock-out of sll0528 gene in wild type Synechocystis sp. PCC 6803 increased their sensitivity to salt, cold and hyperosmotic stress, as revealed by retarded growth, reduced pigments and disrupted photosystems. The sll0528 gene was induced to a much smaller extent by high light and mixotrophic growth with glucose. Similar growth responses of the sll0528 knockout mutant and wild type under high light and mixotrophic growth indicated that sll0528 was dispensable for these conditions. Recombinant Sll0528 protein could cleave beta-casein into smaller fragments. These results together suggest that the Sll0528 metalloprotease plays a role in the stress response and lays the foundation for further investigation of its mechanism, as well as providing hints for the functional analysis of other S2Ps in cyanobacteria.

Cold formability of steels

International Nuclear Information System (INIS)

Lafond, G.; Leclerq, G.; Moliexe, F.; Namdar, R.; Roesch, L.; Sanz, G.

1977-01-01

This work was essentially aimed to the study of the following three questions. Is it possible to assess the cold formability of steels using simple material properties as criteria. What values of mechanical properties can one expect to reach in cold formed parts. Are there simple ways of characterizing the speroidization treatments carried out on steels before cold forming operations. The present report describes the results obtained during this investigation. It is logically divided into three separate parts. Experimental study of cold formability in wire drawing. Influence of metallurgical variables on mechanical properties of high carbon cold drawn wires. Contribution to the study of characterization methods of cold forming steels subjected to a spheroidization heat treatment

Human whole body cold adaptation.

Science.gov (United States)

Daanen, Hein A M; Van Marken Lichtenbelt, Wouter D

2016-01-01

Reviews on whole body human cold adaptation generally do not distinguish between population studies and dedicated acclimation studies, leading to confusing results. Population studies show that indigenous black Africans have reduced shivering thermogenesis in the cold and poor cold induced vasodilation in fingers and toes compared to Caucasians and Inuit. About 40,000 y after humans left Africa, natives in cold terrestrial areas seems to have developed not only behavioral adaptations, but also physiological adaptations to cold. Dedicated studies show that repeated whole body exposure of individual volunteers, mainly Caucasians, to severe cold results in reduced cold sensation but no major physiological changes. Repeated cold water immersion seems to slightly reduce metabolic heat production, while repeated exposure to milder cold conditions shows some increase in metabolic heat production, in particular non-shivering thermogenesis. In conclusion, human cold adaptation in the form of increased metabolism and insulation seems to have occurred during recent evolution in populations, but cannot be developed during a lifetime in cold conditions as encountered in temperate and arctic regions. Therefore, we mainly depend on our behavioral skills to live in and survive the cold.

The impact of cold spells on mortality and effect modification by cold spell characteristics

Science.gov (United States)

Wang, Lijun; Liu, Tao; Hu, Mengjue; Zeng, Weilin; Zhang, Yonghui; Rutherford, Shannon; Lin, Hualiang; Xiao, Jianpeng; Yin, Peng; Liu, Jiangmei; Chu, Cordia; Tong, Shilu; Ma, Wenjun; Zhou, Maigeng

2016-12-01

In China, the health impact of cold weather has received little attention, which limits our understanding of the health impacts of climate change. We collected daily mortality and meteorological data in 66 communities across China from 2006 to 2011. Within each community, we estimated the effect of cold spell exposure on mortality using a Distributed Lag Nonlinear Model (DLNM). We also examined the modification effect of cold spell characteristics (intensity, duration, and timing) and individual-specific factors (causes of death, age, gender and education). Meta-analysis method was finally used to estimate the overall effects. The overall cumulative excess risk (CER) of non-accidental mortality during cold spell days was 28.2% (95% CI: 21.4%, 35.3%) compared with non-cold spell days. There was a significant increase in mortality when the cold spell duration and intensity increased or occurred earlier in the season. Cold spell effects and effect modification by cold spell characteristics were more pronounced in south China. The elderly, people with low education level and those with respiratory diseases were generally more vulnerable to cold spells. Cold spells statistically significantly increase mortality risk in China, with greater effects in southern China. This effect is modified by cold spell characteristics and individual-level factors.

Inductive and electrostatic acceleration in relativistic jet-plasma interactions.

Science.gov (United States)

Ng, Johnny S T; Noble, Robert J

2006-03-24

We report on the observation of rapid particle acceleration in numerical simulations of relativistic jet-plasma interactions and discuss the underlying mechanisms. The dynamics of a charge-neutral, narrow, electron-positron jet propagating through an unmagnetized electron-ion plasma was investigated using a three-dimensional, electromagnetic, particle-in-cell computer code. The interaction excited magnetic filamentation as well as electrostatic plasma instabilities. In some cases, the longitudinal electric fields generated inductively and electrostatically reached the cold plasma-wave-breaking limit, and the longitudinal momentum of about half the positrons increased by 50% with a maximum gain exceeding a factor of 2 during the simulation period. Particle acceleration via these mechanisms occurred when the criteria for Weibel instability were satisfied.

Compilation of information on melter modeling

International Nuclear Information System (INIS)

Eyler, L.L.

1996-03-01

The objective of the task described in this report is to compile information on modeling capabilities for the High-Temperature Melter and the Cold Crucible Melter and issue a modeling capabilities letter report summarizing existing modeling capabilities. The report is to include strategy recommendations for future modeling efforts to support the High Level Waste (BLW) melter development

Cold Shock Induced Protein RBM3 but Not Mild Hypothermia Protects Human SH-SY5Y Neuroblastoma Cells From MPP+-Induced Neurotoxicity

Directory of Open Access Journals (Sweden)

Hai-Jie Yang

2018-05-01

Full Text Available The cold shock protein RBM3 can mediate mild hypothermia-related protection in neurodegeneration such as Alzheimer's disease. However, it remains unclear whether RBM3 and mild hypothermia provide same protection in model of Parkinson's disease (PD, the second most common neurodegenerative disorder. In this study, human SH-SY5Y neuroblastoma cells subjected to insult by 1-methyl-4-phenylpyridinium (MPP+ served as an in-vitro model of PD. Mild hypothermia (32°C aggravated MPP+-induced apoptosis, which was boosted when RBM3 was silenced by siRNA. In contrast, overexpression of RBM3 significantly reduced this apoptosis. MPP+ treatment downregulated the expression of RBM3 both endogenously and exogenously and suppressed its induction by mild hypothermia (32°C. In conclusion, our data suggest that cold shock protein RBM3 provides neuroprotection in a cell model of PD, suggesting that RBM3 induction may be a suitable strategy for PD therapy. However, mild hypothermia exacerbates MPP+-induced apoptosis even that RBM3 could be synthesized during mild hypothermia.

Inductive reasoning.

Science.gov (United States)

Hayes, Brett K; Heit, Evan; Swendsen, Haruka

2010-03-01

Inductive reasoning entails using existing knowledge or observations to make predictions about novel cases. We review recent findings in research on category-based induction as well as theoretical models of these results, including similarity-based models, connectionist networks, an account based on relevance theory, Bayesian models, and other mathematical models. A number of touchstone empirical phenomena that involve taxonomic similarity are described. We also examine phenomena involving more complex background knowledge about premises and conclusions of inductive arguments and the properties referenced. Earlier models are shown to give a good account of similarity-based phenomena but not knowledge-based phenomena. Recent models that aim to account for both similarity-based and knowledge-based phenomena are reviewed and evaluated. Among the most important new directions in induction research are a focus on induction with uncertain premise categories, the modeling of the relationship between inductive and deductive reasoning, and examination of the neural substrates of induction. A common theme in both the well-established and emerging lines of induction research is the need to develop well-articulated and empirically testable formal models of induction. Copyright © 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website. Copyright © 2010 John Wiley & Sons, Ltd.

Cold/menthol TRPM8 receptors initiate the cold-shock response and protect germ cells from cold-shock-induced oxidation.

Science.gov (United States)

Borowiec, Anne-Sophie; Sion, Benoit; Chalmel, Frédéric; D Rolland, Antoine; Lemonnier, Loïc; De Clerck, Tatiana; Bokhobza, Alexandre; Derouiche, Sandra; Dewailly, Etienne; Slomianny, Christian; Mauduit, Claire; Benahmed, Mohamed; Roudbaraki, Morad; Jégou, Bernard; Prevarskaya, Natalia; Bidaux, Gabriel

2016-09-01

Testes of most male mammals present the particularity of being externalized from the body and are consequently slightly cooler than core body temperature (4-8°C below). Although, hypothermia of the testis is known to increase germ cells apoptosis, little is known about the underlying molecular mechanisms, including cold sensors, transduction pathways, and apoptosis triggers. In this study, using a functional knockout mouse model of the cold and menthol receptors, dubbed transient receptor potential melastatine 8 (TRPM8) channels, we found that TRPM8 initiated the cold-shock response by differentially modulating cold- and heat-shock proteins. Besides, apoptosis of germ cells increased in proportion to the cooling level in control mice but was independent of temperature in knockout mice. We also observed that the rate of germ cell death correlated positively with the reactive oxygen species level and negatively with the expression of the detoxifying enzymes. This result suggests that the TRPM8 sensor is a key determinant of germ cell fate under hypothermic stimulation.-Borowiec, A.-S., Sion, B., Chalmel, F., Rolland, A. D., Lemonnier, L., De Clerck, T., Bokhobza, A., Derouiche, S., Dewailly, E., Slomianny, C., Mauduit, C., Benahmed, M., Roudbaraki, M., Jégou, B., Prevarskaya, N., Bidaux, G. Cold/menthol TRPM8 receptors initiate the cold-shock response and protect germ cells from cold-shock-induced oxidation. © The Author(s).

Antibody induction versus corticosteroid induction for liver transplant recipients

DEFF Research Database (Denmark)

Penninga, Luit; Wettergren, André; Wilson, Colin H

2014-01-01

BACKGROUND: Liver transplantation is an established treatment option for end-stage liver failure. To date, no consensus has been reached on the use of immunosuppressive T-cell specific antibody induction compared with corticosteroid induction of immunosuppression after liver transplantation....... OBJECTIVES: To assess the benefits and harms of T-cell specific antibody induction versus corticosteroid induction for prevention of acute rejection in liver transplant recipients. SEARCH METHODS: We searched The Cochrane Hepato-Biliary Group Controlled Trials Register, the Cochrane Central Register...... to identify additional trials. SELECTION CRITERIA: We included all randomised clinical trials assessing immunosuppression with T-cell specific antibody induction versus corticosteroid induction in liver transplant recipients. Our inclusion criteria stated that participants within each included trial should...

Cold stress alters transcription in meiotic anthers of cold tolerant chickpea (Cicer arietinum L.).

Science.gov (United States)

Sharma, Kamal Dev; Nayyar, Harsh

2014-10-11

Cold stress at reproductive phase in susceptible chickpea (Cicer arietinum L.) leads to pollen sterility induced flower abortion. The tolerant genotypes, on the other hand, produce viable pollen and set seed under cold stress. Genomic information on pollen development in cold-tolerant chickpea under cold stress is currently unavailable. DDRT-PCR analysis was carried out to identify anther genes involved in cold tolerance in chickpea genotype ICC16349 (cold-tolerant). A total of 9205 EST bands were analyzed. Cold stress altered expression of 127 ESTs (90 up-regulated, 37 down-regulated) in anthers, more than two third (92) of which were novel with unknown protein identity and function. Remaining about one third (35) belonged to several functional categories such as pollen development, signal transduction, ion transport, transcription, carbohydrate metabolism, translation, energy and cell division. The categories with more number of transcripts were carbohydrate/triacylglycerol metabolism, signal transduction, pollen development and transport. All but two transcripts in these categories were up-regulated under cold stress. To identify time of regulation after stress and organ specificity, expression levels of 25 differentially regulated transcripts were also studied in anthers at six time points and in four organs (anthers, gynoecium, leaves and roots) at four time points. Limited number of genes were involved in regulating cold tolerance in chickpea anthers. Moreover, the cold tolerance was manifested by up-regulation of majority of the differentially expressed transcripts. The anthers appeared to employ dual cold tolerance mechanism based on their protection from cold by enhancing triacylglycerol and carbohydrate metabolism; and maintenance of normal pollen development by regulating pollen development genes. Functional characterization of about two third of the novel genes is needed to have precise understanding of the cold tolerance mechanisms in chickpea anthers.

Gene-expression analysis of cold-stress response in the sexually transmitted protist Trichomonas vaginalis.

Science.gov (United States)

Fang, Yi-Kai; Huang, Kuo-Yang; Huang, Po-Jung; Lin, Rose; Chao, Mei; Tang, Petrus

2015-12-01

Trichomonas vaginalis is the etiologic agent of trichomoniasis, the most common nonviral sexually transmitted disease in the world. This infection affects millions of individuals worldwide annually. Although direct sexual contact is the most common mode of transmission, increasing evidence indicates that T. vaginalis can survive in the external environment and can be transmitted by contaminated utensils. We found that the growth of T. vaginalis under cold conditions is greatly inhibited, but recovers after placing these stressed cells at the normal cultivation temperature of 37 °C. However, the mechanisms by which T. vaginalis regulates this adaptive process are unclear. An expressed sequence tag (EST) database generated from a complementary DNA library of T. vaginalis messenger RNAs expressed under cold-culture conditions (4 °C, TvC) was compared with a previously published normal-cultured EST library (37 °C, TvE) to assess the cold-stress responses of T. vaginalis. A total of 9780 clones were sequenced from the TvC library and were mapped to 2934 genes in the T. vaginalis genome. A total of 1254 genes were expressed in both the TvE and TvC libraries, and 1680 genes were only found in the TvC library. A functional analysis showed that cold temperature has effects on many cellular mechanisms, including increased H2O2 tolerance, activation of the ubiquitin-proteasome system, induction of iron-sulfur cluster assembly, and reduced energy metabolism and enzyme expression. The current study is the first large-scale transcriptomic analysis in cold-stressed T. vaginalis and the results enhance our understanding of this important protist. Copyright © 2014. Published by Elsevier B.V.

Cough & Cold Medicine Abuse

Science.gov (United States)

... Videos for Educators Search English Español Cough & Cold Medicine Abuse KidsHealth / For Teens / Cough & Cold Medicine Abuse ... resfriado Why Do People Use Cough and Cold Medicines to Get High? There's an ingredient in many ...

Induction linacs

International Nuclear Information System (INIS)

Keefe, D.

1986-07-01

The principle of linear induction acceleration is described, and examples are given of practical configurations for induction linacs. These examples include the Advanced Technology Accelerator, Long Pulse Induction Linac, Radial Line Accelerator (RADLAC), and Magnetically-Insulated Electron-Focussed Ion Linac. A related concept, the auto accelerator, is described in which the high-current electron-beam technology in the sub-10 MeV region is exploited to produce electron beams at energies perhaps as high as the 100 to 1000 MeV range. Induction linacs for ions are also discussed. The efficiency of induction linear acceleration is analyzed

Antibody induction versus placebo, no induction, or another type of antibody induction for liver transplant recipients

DEFF Research Database (Denmark)

Penninga, Luit; Wettergren, André; Wilson, Colin H

2014-01-01

. All 19 trials were with high risk of bias. Of the 19 trials, 16 trials were two-arm trials, and three trials were three-arm trials. Hence, we found 25 trial comparisons with antibody induction agents: interleukin-2 receptor antagonist (IL-2 RA) versus no induction (10 trials with 1454 participants....... Furthermore, serum creatinine was statistically significantly higher when T-cell specific antibody induction was compared with no induction (MD 3.77 μmol/L, 95% CI 0.33 to 7.21; low-quality evidence), as well as when polyclonal T-cell specific antibody induction was compared with no induction, but this small...... T-cell specific antibody induction, drug-related adverse events were less common among participants treated with interleukin-2 receptor antagonists (RR 0.23, 95% CI 0.09 to 0.63; low-quality evidence), but this was caused by the results from one trial, and trial sequential analysis could not exclude...

CD36 is indispensable for thermogenesis under conditions of fasting and cold stress

Energy Technology Data Exchange (ETDEWEB)

Putri, Mirasari [Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Department of Public Health, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Syamsunarno, Mas Rizky A.A. [Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Department of Biochemistry, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM 21, Jatinangor, West Java 45363 (Indonesia); Iso, Tatsuya, E-mail: isot@gunma-u.ac.jp [Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Education and Research Support Center, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Yamaguchi, Aiko; Hanaoka, Hirofumi [Department of Bioimaging Information Analysis, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Sunaga, Hiroaki [Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Koitabashi, Norimichi [Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Matsui, Hiroki [Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Yamazaki, Chiho; Kameo, Satomi [Department of Public Health, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); Tsushima, Yoshito [Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511 (Japan); and others

2015-02-20

Hypothermia can occur during fasting when thermoregulatory mechanisms, involving fatty acid (FA) utilization, are disturbed. CD36/FA translocase is a membrane protein which facilitates membrane transport of long-chain FA in the FA consuming heart, skeletal muscle (SkM) and adipose tissues. It also accelerates uptake of triglyceride-rich lipoprotein by brown adipose tissue (BAT) in a cold environment. In mice deficient for CD36 (CD36{sup −/−} mice), FA uptake is markedly reduced with a compensatory increase in glucose uptake in the heart and SkM, resulting in lower levels of blood glucose especially during fasting. However, the role of CD36 in thermogenic activity during fasting remains to be determined. In fasted CD36{sup −/−} mice, body temperature drastically decreased shortly after cold exposure. The hypothermia was accompanied by a marked reduction in blood glucose and in stores of triacylglycerols in BAT and of glycogen in glycolytic SkM. Biodistribution analysis using the FA analogue {sup 125}I-BMIPP and the glucose analogue {sup 18}F-FDG revealed that uptake of FA and glucose was severely impaired in BAT and glycolytic SkM in cold-exposed CD36{sup −/−} mice. Further, induction of the genes of thermogenesis in BAT was blunted in fasted CD36{sup −/−} mice after cold exposure. These findings strongly suggest that CD36{sup −/−} mice exhibit pronounced hypothermia after fasting due to depletion of energy storage in BAT and glycolytic SkM and to reduced supply of energy substrates to these tissues. Our study underscores the importance of CD36 for nutrient homeostasis to survive potentially life-threatening challenges, such as cold and starvation. - Highlights: • We examined the role of CD36 in thermogenesis during cold exposure. • CD36{sup −/−} mice exhibit rapid hypothermia after cold exposure during fasting. • Uptake of fatty acid and glucose is impaired in thermogenic tissues during fasting. • Storage of energy substrates is

Corrosion Resistance of Murataite-Based Ceramics Containing Simulated Actinide/Rare Earth Fraction of High Level Waste

International Nuclear Information System (INIS)

Stefanovsky, S.V.; Varlakova, G.A.; Burlaka, O.A.; Stefanovsky, O.I.; Nikonov, B.S.; Yudintsev, S.V.

2009-01-01

Two samples of murataite-based ceramics containing simulated Actinide/Rare Earth (An/RE) fraction of high level waste (HLW) produced by a cold crucible inductive melting (CCIM) were tested using a single-pass-flow-through (SPFT) procedure. As-prepared and leached samples were examined by X-ray diffraction (XRD) and scanning electron microscopy with energy dispersive system (SEM/EDS). The as-prepared ceramics were composed of murataite, perovskite and crichtonite as well as minor zirconolite and rutile (in one sample). Elemental concentrations at pH=2 and T=90 deg. C were measured and leach rates were calculated. Perovskite concentrating Ca and Ce-group REs (La, Ce, Pr, Nd) was found to be the lowest durable phase. Leach rates of Ca and Ce-group REs (Ce, Nd) from the sample with higher perovskite content were found to be higher than those of U and Zr by one to three orders of magnitude. Elemental leach rates from the ceramic with lower perovskite content are lower by up to 10 times. (authors)

Commemoration of a cold war

DEFF Research Database (Denmark)

Farbøl, Rosanna

2015-01-01

This article brings together the fields of Cold War studies and memory studies. In Denmark, a remarkable institutionalisation of Cold War memory has taken place in the midst of a heated ideological battle over the past and whether to remember the Cold War as a ‘war’. Using Danish Cold War museums...... and heritage sites as case studies, this article sheds new light on the politics of history involved in Cold War commemoration. It suggests that the Cold War is commemorated as a war, yet this war memory is of a particular kind: it is a war memory without victims....

Cold thermal injury from cold caps used for the prevention of chemotherapy-induced alopecia.

Science.gov (United States)

Belum, Viswanath Reddy; de Barros Silva, Giselle; Laloni, Mariana Tosello; Ciccolini, Kathryn; Goldfarb, Shari B; Norton, Larry; Sklarin, Nancy T; Lacouture, Mario E

2016-06-01

The use of scalp cooling for the prevention of chemotherapy-induced alopecia (CIA) is increasing. Cold caps are placed onto the hair-bearing areas of the scalp for varying time periods before, during, and after cytotoxic chemotherapy. Although not yet reported, improper application procedures could result in adverse events (AEs). At present, there are no evidence-based scalp cooling protocols, and there is no regulatory oversight of their use. To report the occurrence of cold thermal injury (frostbite) on the scalp, following the use of cold caps for the prevention of CIA. We identified four patients who developed cold thermal injuries on the scalp following the application of cold caps. Medical records were analyzed to retrieve the demographic and clinical characteristics. The cold thermal injuries in our patients were grade 1/2 in severity and improved with topical interventions and interruption of cold cap use, although grade 1 persistent alopecia ensued in 3 patients. The true incidence of such injuries in this setting, however, remains unknown. Cold thermal injuries are likely infrequent and preventable AEs that may result from improper device application procedures during cold cap use. Although these untoward events are usually mild to moderate in severity, the potential occurrence of long-term sequelae (e.g., permanent alopecia and scarring) or the need to discontinue cold cap use, are not known. Prospective studies are needed to further elucidate the risk and standardize healthcare delivery methods, and to improve patient/supportive/healthcare provider education.

The R and D and commercial experience on KHNP's vitrification technology

International Nuclear Information System (INIS)

Jo, Hyun-Jun; Kim, Cheon-Woo

2015-01-01

The Korea Hydro and Nuclear Power Co., Ltd., (KHNP) has investigated and evaluated various efficient thermal treatment technologies for the LILW. In 1994 and 1995, the feasibility of several melter technologies was assessed from technical and economic perspectives. Finally, the R and D project to develop the vitrification technology using CCIM (Cold Crucible Induction Melter) and PTM (Plasma Torch Melter) was launched in 1997. This R and D project had been completed from 1997 to 2002. KHNP started the project to construct the commercial facility using the results of the R and D project in 2002. The HanUl Vitrification Facility (UVF), to be used for the vitirification of low-and intermediate-level radioactive waste (LILW) generated by nuclear power plants (NPPs), is the world's first commercial facility using CCIM technology. The design of UVF had been conducted from 2002 to 2005. The construction was begun in 2005 and was completed in 2007. From 2007 to 2009, all key performance tests, such as the system functional test, the cold test, the hot test, and the real waste test, were successfully carried out. The UVF commenced the commercial operation in October 2009. Based on the successful construction and operation of UVF, the advanced R and D project has been started to develop the large-scale vitrification facility. (author)

Cold urticaria: inhibition of cold-induced histamine release by doxantrazole.

Science.gov (United States)

Bentley-Phillips, C B; Eady, R A; Greaves, M W

1978-10-01

Thirteen patients with cold urticaria were studied to assess the effect of the systemic drug doxantrazole, which has actions resembling disodium cromoglycate, on cold evoked histamine release. The patients, all of whom developed an immediate local whealing response after cooling of the forearm, demonstrated release of histamine into venous blood draining that forearm. Following doxantrazole treatment, significant suppression of histamine release occurred. In some but not all patients this was accompanied by diminution of urtication in response to cooling. A double-blind study was carried out in 3 subjects, all of whom showed diminished cold-stimulated histamine release after doxantrazole. Two of these showed clinical improvement. Doxantrazole had no effect on erythema due to intradermal histamine, but did suppress the erythematous reaction to intradermal injection of compound 48/80. Our results suggest that doxantrazole or related anti-allergic agents might be useful in the treatment of cold urticaria.

The Effect of Spermidine on Cold Tolerance Induction in Cucumber Seedlings ‘Cv. Super-Dominus’

Directory of Open Access Journals (Sweden)

Golnar GhazianTafrishi

2017-09-01

Full Text Available Introduction: Plants native to tropical and subtropical climates which grown in the temperate climate zone, suffer chilling injury when exposed to non-freezing temperatures for a certain period of time. The optimum growth temperature for cucumber (a tropical plant is 20 to 25°C. Cucumber is sensitive to temperatures lower than 10 °C. Cucumber area of production exposes to late spring and early autumn cold weather in Khorasan-e-Razavai, Iran. Studies showed that chilling leads to an alteration in fatty acid composition of membrane lipids and its permeability, changes in photosynthetic pigments content and decrease in photosynthesis. Many researchers pointed to a possible role of polyamine compounds in plant defense against environmental stresses. Exog enous application Spd could prevent the electrolyte and amino acid leakage or recovering the plasma membrane damage in rice and cucumber in response to salinity, chilling and water stressed conditions. Materials and methods: A factorial experiment, based on completely randomized design was conducted to investigate the effect of short-term chilling on cucumber plantlets which was earlier treated with spermidine. Factors were included two levels of temperature (6 and 12°C and four levels of spermidine (0, 0.25, 0.5 and .0.75 mg/L. The studied cultivar was ‘Super-Dominus’. In order to determine the extent of chilling injury, plants of each treatment were rated based on visual symptoms. By assigning values of 1, 2, 3, 4, and 5 while 1: no visible symptoms 2:5% of leaf area necrotic, 3: 5-25% of leaf area necrotic, 4: 26-50% of leaf area necrotic but plant still alive, 5: lost, entire plant necrotic and collapsed. Measured traits were root and shoot length, root and shoot dry weight, root and leaf electrical leakage, and leaf chlorophyll content. Results and discussion: Plants which exposed to low temperature showed chilling injury symptoms (5-25% leaf area necrotic. The symptoms reduced (less

Scanning/friction force microscopy study of YBa2Cu3O7-δ single crystals grown in BaZrO3 crucibles

International Nuclear Information System (INIS)

Lang, H.P.; Jess, P.; Hubler, U.

1996-01-01

Very pure YBa 2 Cu 3 O 7-δ (YBCO) single crystals grown in BaZrO 3 crucibles are studied in the as-grown and the oxidized state by scanning force (SFM), friction force (FFM) and scanning tunneling microscopies (STM). The images show clean terraces with step-heights of one unit cell along YBCO(001), i.e. 1.2 nm. Only close to step edges is material contrast observed by FFM indicating traces of flux. Some crystal surfaces exhibit over-layer features, such as star-like, ribbon-like and checkerboard-like structures, which exhibit friction contrast implying the presence of different materials on the surface. Tunneling spectroscopy at 4-7 K in high vacuum reveals a superconducting energy gap of 2Δ ∼ 26 meV

77 FR 43117 - Meeting of the Cold War Advisory Committee for the Cold War Theme Study

Science.gov (United States)

2012-07-23

... the Cold War Advisory Committee for the Cold War Theme Study AGENCY: National Park Service, Interior... Committee Act, 5 U.S.C. Appendix, that the Cold War Advisory Committee for the Cold War Theme Study will... National Park Service (NPS) concerning the Cold War Theme Study. DATES: The teleconference meeting will be...

Development of Cold Neutron Activation Station at HANARO Cold Neutron Source

International Nuclear Information System (INIS)

Sun, G. M.; Hoang, S. M. T.; Moon, J. H.; Chung, Y. S.; Cho, S. J.; Lee, K. H.; Park, B. G.; Choi, H. D.

2012-01-01

A new cold neutron source at the HANARO Research Reactor had been constructed in the framework of a five-year project, and ended in 2009. It has seven neutron guides, among which five guides were already allocated for a number of neutron scattering instruments. A new two-year project to develop a Cold Neutron Activation Station (CONAS) was carried out at the two neutron guides since May 2010, which was supported by the program of the Ministry of Education, Science and Technology, Korea. Fig. 1 shows the location of CONAS. CONAS is a complex facility including several radioanalytical instruments utilizing neutron capture reaction to analyze elements in a sample. It was designed to include three instruments like a CN-PGAA (Cold Neutron - Prompt Gamma Activation Analysis), a CN-NIPS (Cold Neutron - Neutron Induced Pair Spectrometer), and a CN-NDP (Cold Neutron - Neutron-induced prompt charged particle Depth Profiling). Fig. 2 shows the conceptual configuration of the CONAS concrete bioshield and the instruments. CN-PGAA and CN-NIPS measure the gamma-rays promptly emitted from the sample after neutron capture, whereas CN-NDP is a probe to measure the charged particles emitted from the sample surface after neutron capture. For this, we constructed two cold neutron guides called CG1 and CG2B guides from the CNS

Support for cold neutron utilization

International Nuclear Information System (INIS)

Lee, Kye Hong; Han, Young Soo; Choi, Sungmin; Choi, Yong; Kwon, Hoon; Lee, Kwang Hee

2012-06-01

- Support for experiments by users of cold neutron scattering instrument - Short-term training of current and potential users of cold neutron scattering instrument for their effective use of the instrument - International collaboration for advanced utilization of cold neutron scattering instruments - Selection and training of qualified instrument scientists for vigorous research endeavors and outstanding achievements in experiments with cold neutron - Research on nano/bio materials using cold neutron scattering instruments - Bulk nano structure measurement using small angle neutron scattering and development of analysis technique

The Nav1.9 Channel Is a Key Determinant of Cold Pain Sensation and Cold Allodynia

Directory of Open Access Journals (Sweden)

Stéphane Lolignier

2015-05-01

Full Text Available Cold-triggered pain is essential to avoid prolonged exposure to harmfully low temperatures. However, the molecular basis of noxious cold sensing in mammals is still not completely understood. Here, we show that the voltage-gated Nav1.9 sodium channel is important for the perception of pain in response to noxious cold. Nav1.9 activity is upregulated in a subpopulation of damage-sensing sensory neurons responding to cooling, which allows the channel to amplify subthreshold depolarizations generated by the activation of cold transducers. Consequently, cold-triggered firing is impaired in Nav1.9−/− neurons, and Nav1.9 null mice and knockdown rats show increased cold pain thresholds. Disrupting Nav1.9 expression in rodents also alleviates cold pain hypersensitivity induced by the antineoplastic agent oxaliplatin. We conclude that Nav1.9 acts as a subthreshold amplifier in cold-sensitive nociceptive neurons and is required for the perception of cold pain under normal and pathological conditions.

Cold temperatures increase cold hardiness in the next generation Ophraella communa beetles.

Directory of Open Access Journals (Sweden)

Zhong-Shi Zhou

Full Text Available The leaf beetle, Ophraella communa, has been introduced to control the spread of the common ragweed, Ambrosia artemisiifolia, in China. We hypothesized that the beetle, to be able to track host-range expansion into colder climates, can phenotypically adapt to cold temperatures across generations. Therefore, we questioned whether parental experience of colder temperatures increases cold tolerance of the progeny. Specifically, we studied the demography, including development, fecundity, and survival, as well as physiological traits, including supercooling point (SCP, water content, and glycerol content of O. communa progeny whose parents were maintained at different temperature regimes. Overall, the entire immature stage decreased survival of about 0.2%-4.2% when parents experienced cold temperatures compared to control individuals obtained from parents raised at room temperature. However, intrinsic capacity for increase (r, net reproductive rate (R 0 and finite rate of increase (λ of progeny O. communa were maximum when parents experienced cold temperatures. Glycerol contents of both female and male in progeny was significantly higher when maternal and paternal adults were cold acclimated as compared to other treatments. This resulted in the supercooling point of the progeny adults being significantly lower compared to beetles emerging from parents that experienced room temperatures. These results suggest that cold hardiness of O. communa can be promoted by cold acclimation in previous generation, and it might counter-balance reduced survival in the next generation, especially when insects are tracking their host-plants into colder climates.

PHYSIOLOGICAL AND LEUKOCYTE SUBSET RESPONSES TO EXERCISE AND COLD EXPOSURE IN COLD-ACCLIMATIZED SKATERS

Directory of Open Access Journals (Sweden)

K. Kim

2014-07-01

Full Text Available We investigated physiological responses and changes in circulating immune cells following exercise in cold and thermoneutral conditions. Participants were short track skaters (n=9 who were acclimatized to cold conditions, and inline skaters (n=10 who were not acclimatized. All skaters were young, and skating at a recreational level three days per week for at least one year. Using a cross-over design, study variables were measured during 60 min of submaximal cycling (65% ·VO2max in cold (ambient temperature: 5±1°C, relative humidity: 41±9% and thermoneutral conditions (ambient temperature: 21±1°C, relative humidity: 35±5%. Heart rate, blood lactate and tympanic temperature were measured at rest, during exercise and recovery. Plasma cortisol, calprotectin and circulating blood cell numbers were measured before and after 60 min of cold or thermoneutral conditions, and during recovery from exercise. Heart rate was lower in both groups during exercise in cold versus thermoneutral conditions (P<0.05. The increase in total leukocytes during recovery was primarily due to an increase in neutrophils in both groups. The cold-acclimatized group activated neutrophils after exercise in cold exposure, whereas the non-acclimatized group activated lymphocyte and cortisol after exercise in cold exposure. Lymphocyte subsets significantly changed in both groups over time during recovery as compared to rest. Immediately after exercise in both groups, CD16+ and CD69+ cells were elevated compared to rest or before exercise in both conditions. Acclimatization to exercise in the cold does not appear to influence exercise-induced immune changes in cold conditions, with the possible exception of neutrophils, lymphocytes and cortisol concentration.

Thermographic skin temperature measurement compared with cold sensation in predicting the efficacy and distribution of epidural anesthesia.

Science.gov (United States)

Bruins, Arnoud A; Kistemaker, Kay R J; Boom, Annemieke; Klaessens, John H G M; Verdaasdonk, Rudolf M; Boer, Christa

2018-04-01

Due to the high rates of epidural failure (3-32%), novel techniques are required to objectively assess the successfulness of an epidural block. In this study we therefore investigated whether thermographic temperature measurements have a higher predictive value for a successful epidural block when compared to the cold sensation test as gold standard. Epidural anesthesia was induced in 61 patients undergoing elective abdominal, thoracic or orthopedic surgery. A thermographic picture was recorded at 5, 10 and 15 min following epidural anesthesia induction. After 15 min a cold sensation test was performed. Epidural anesthesia is associated with a decrease in skin temperature. Thermography predicts a successful epidural block with a sensitivity of 54% and a PPV of 92% and a specificity of 67% and a NPV of 17%. The cold sensation test shows a higher sensitivity and PPV than thermography (97 and 93%), but a lower specificity and NPV than thermography (25 and 50%). Thermographic temperature measurements can be used as an additional and objective method for the assessment of the effectiveness of an epidural block next to the cold sensation test, but have a low sensitivity and negative predictive value. The local decrease in temperature as observed in our study during epidural anesthesia is mainly attributed to a core-to-peripheral redistribution of body heat and vasodilation.

Cold fusion, Alchemist's dream

International Nuclear Information System (INIS)

Clayton, E.D.

1989-09-01

In this report the following topics relating to cold fusion are discussed: muon catalysed cold fusion; piezonuclear fusion; sundry explanations pertaining to cold fusion; cosmic ray muon catalysed cold fusion; vibrational mechanisms in excited states of D 2 molecules; barrier penetration probabilities within the hydrogenated metal lattice/piezonuclear fusion; branching ratios of D 2 fusion at low energies; fusion of deuterons into 4 He; secondary D+T fusion within the hydrogenated metal lattice; 3 He to 4 He ratio within the metal lattice; shock induced fusion; and anomalously high isotopic ratios of 3 He/ 4 He

Cold neutron production and application

International Nuclear Information System (INIS)

Inoue, Kazuhiko; Watanabe, Noboru.

1976-01-01

The first part gives general introduction to cold neutrons, namely the definition and the role as a probe in basic science and technology. The second part reviews various methods of cold neutron production. Some physical characteristics required for cold moderators are presented, and a list summarizes a number of cold moderators and their reactor physics constants. The definition of flux gain factor and the measured values for liquid light- and heavy-hydrogen are also given. The cold neutron spectra in methane and liquid hydrogen measured by LINAC time-of-flight method are presented to show the advantage of solid methane. The cold neutron sources using experimental reactors or linear accelerators are explained along with the examples of existing facilities. Two Japanese programs, the one is the use of a high flux reactor and the other is the use of a LINAC, are also presented. The third part of this report reviews the application areas of cold neutrons. (Aoki, K.)

Effects of cold temperatures on the excitability of rat trigeminal ganglion neurons that are not for cold-sensing

Science.gov (United States)

Kanda, Hirosato; Gu, Jianguo G.

2016-01-01

Except a small population of primary afferent neurons for sensing cold to generate the sensations of innocuous and noxious cold, it is generally believed that cold temperatures suppress the excitability of other primary afferent neurons that are not for cold-sensing. These not-for-cold-sensing neurons include the majority of non-nociceptive and nociceptive afferent neurons. In the present study we have found that not-for-cold-sensing neurons of rat trigeminal ganglia (TG) change their excitability in several ways at cooling temperatures. In nearly 70% of not-for-cold-sensing TG neurons, the cooling temperature of 15°C increases their membrane excitability. We regard these neurons as cold-active neurons. For the remaining 30% of not-for-cold-sensing TG neurons, the cooling temperature of 15°C either has no effect (regarded as cold-ineffective neurons) or suppress (regarded as cold-suppressive neurons) their membrane excitability. For cold-active neurons, the cold temperature of 15°C increases their excitability as is evidenced by the increases in action potential (AP) firing numbers and/or reduction of AP rheobase when these neurons are depolarized electrically. The cold temperature of 15°C significantly inhibits M-currents and increases membrane input resistance of cold-active neurons. Retigabine, an M-current activator, abolishes the effect of cold temperatures on AP firing but not the effect of cold temperature on AP rheobase levels. The inhibition of M-currents and the increases of membrane input resistance are likely two mechanisms by which cooling temperatures increase the excitability of not-for-cold-sensing TG neurons. PMID:26709732

The Nav1.9 channel is a key determinant of cold pain sensation and cold allodynia.

Science.gov (United States)

Lolignier, Stéphane; Bonnet, Caroline; Gaudioso, Christelle; Noël, Jacques; Ruel, Jérôme; Amsalem, Muriel; Ferrier, Jérémy; Rodat-Despoix, Lise; Bouvier, Valentine; Aissouni, Youssef; Prival, Laetitia; Chapuy, Eric; Padilla, Françoise; Eschalier, Alain; Delmas, Patrick; Busserolles, Jérôme

2015-05-19

Cold-triggered pain is essential to avoid prolonged exposure to harmfully low temperatures. However, the molecular basis of noxious cold sensing in mammals is still not completely understood. Here, we show that the voltage-gated Nav1.9 sodium channel is important for the perception of pain in response to noxious cold. Nav1.9 activity is upregulated in a subpopulation of damage-sensing sensory neurons responding to cooling, which allows the channel to amplify subthreshold depolarizations generated by the activation of cold transducers. Consequently, cold-triggered firing is impaired in Nav1.9(-/-) neurons, and Nav1.9 null mice and knockdown rats show increased cold pain thresholds. Disrupting Nav1.9 expression in rodents also alleviates cold pain hypersensitivity induced by the antineoplastic agent oxaliplatin. We conclude that Nav1.9 acts as a subthreshold amplifier in cold-sensitive nociceptive neurons and is required for the perception of cold pain under normal and pathological conditions. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

Cold-Weather Sports

Science.gov (United States)

... Videos for Educators Search English Español Cold-Weather Sports KidsHealth / For Teens / Cold-Weather Sports What's in this article? What to Do? Classes ... weather. What better time to be outdoors? Winter sports can help you burn calories, increase your cardiovascular ...

Cold fusion

International Nuclear Information System (INIS)

Koster, J.

1989-01-01

In this contribution the author the phenomenom of so-called cold fusion, inspired by the memorable lecture of Moshe Gai on his own search for this effect. Thus much of what follows was presented by Dr. Gai; the rest is from independent reading. What is referred to as cold fusion is of course the observation of possible products of deuteron-deuteron (d-d) fusion within deuterium-loaded (dentended) electrodes. The debate over the two vanguard cold fusion experiments has raged under far more public attention than usually accorded new scientific phenomena. The clamor commenced with the press conference of M. Fleishmann and S. Pons on March 23, 1989 and the nearly simultaneous wide circulation of a preprint of S. Jones and collaborators. The majority of work attempting to confirm these observations has at the time of this writing yet to appear in published form, but contributions to conferences and electronic mail over computer networks were certainly filled with preliminary results. To keep what follows to a reasonable length the author limit this discussion to the searches for neutron (suggested by ref. 2) or for excessive heat production (suggested by ref. 1), following a synopsis of the hypotheses of cold fusion

Analysis of ethylene biosynthesis and perception during postharvest cold storage of Marsh and Star Ruby grapefruits.

Science.gov (United States)

Lado, Joanna; Rodrigo, María Jesús; Zacarías, Lorenzo

2015-10-01

Grapefruits are among the citrus species more sensitive to cold and develop chilling injury symptoms during prolonged postharvest storage at temperatures lower than 8 ℃-10 ℃. The plant hormone ethylene has been described either to protect or potentiate chilling injury development in citrus whereas little is known about transcriptional regulation of ethylene biosynthesis, perception and response during cold storage and how the hormone is regulating its own perception and signaling cascade. Then, the objective of the present study was to explore the transcriptional changes in the expression of ethylene biosynthesis, receptors and response genes during cold storage of the white Marsh and the red Star Ruby grapefruits. The effect of the ethylene action inhibitor, 1-MCP, was evaluated to investigate the involvement of ethylene in the regulation of the genes of its own biosynthesis and perception pathway. Ethylene production was very low at the harvest time in fruits of both varieties and experienced only minor changes during storage. By contrast, inhibition of ethylene perception by 1-MCP markedly induced ethylene production, and this increase was highly stimulated during shelf-life at 20 ℃, as well as transcription of ACS and ACO. These results support the auto-inhibitory regulation of ethylene in grapefruits, which acts mainly at the transcriptional level of ACS and ACO genes. Moreover, ethylene receptor1 and ethylene receptor3 were induced by cold while no clear role of ethylene was observed in the induction of ethylene receptors. However, ethylene appears to be implicated in the transcriptional regulation of ERFs both under cold storage and shelf-life. © The Author(s) 2014.

Induction machine handbook

CERN Document Server

Boldea, Ion

2002-01-01

Often called the workhorse of industry, the advent of power electronics and advances in digital control are transforming the induction motor into the racehorse of industrial motion control. Now, the classic texts on induction machines are nearly three decades old, while more recent books on electric motors lack the necessary depth and detail on induction machines.The Induction Machine Handbook fills industry's long-standing need for a comprehensive treatise embracing the many intricate facets of induction machine analysis and design. Moving gradually from simple to complex and from standard to

Cold acclimation and cognitive performance: A review.

Science.gov (United States)

Jones, Douglas M; Bailey, Stephen P; Roelands, Bart; Buono, Michael J; Meeusen, Romain

2017-12-01

Athletes, occupational workers, and military personnel experience cold temperatures through cold air exposure or cold water immersion, both of which impair cognitive performance. Prior work has shown that neurophysiological pathways may be sensitive to the effects of temperature acclimation and, therefore, cold acclimation may be a potential strategy to attenuate cold-induced cognitive impairments for populations that are frequently exposed to cold environments. This review provides an overview of studies that examine repeated cold stress, cold acclimation, and measurements of cognitive performance to determine whether or not cold acclimation provides beneficial protection against cold-induced cognitive performance decrements. Studies included in this review assessed cognitive measures of reaction time, attention, logical reasoning, information processing, and memory. Repeated cold stress, with or without evidence of cold acclimation, appears to offer no added benefit of improving cognitive performance. However, research in this area is greatly lacking and, therefore, it is difficult to draw any definitive conclusions regarding the use of cold acclimation to improve cognitive performance during subsequent cold exposures. Given the current state of minimal knowledge on this topic, athletes, occupational workers, and military commands looking to specifically enhance cognitive performance in cold environments would likely not be advised to spend the time and effort required to become acclimated to cold. However, as more knowledge becomes available in this area, recommendations may change. Copyright © 2017 Elsevier B.V. All rights reserved.

Human whole body cold adaptation.

OpenAIRE

Daanen, Hein A.M.; Van Marken Lichtenbelt, Wouter D.

2016-01-01

ABSTRACT Reviews on whole body human cold adaptation generally do not distinguish between population studies and dedicated acclimation studies, leading to confusing results. Population studies show that indigenous black Africans have reduced shivering thermogenesis in the cold and poor cold induced vasodilation in fingers and toes compared to Caucasians and Inuit. About 40,000?y after humans left Africa, natives in cold terrestrial areas seems to have developed not only behavioral adaptations...

Human whole body cold adaptation.

NARCIS (Netherlands)

Daanen, Hein A.M.; Van Marken Lichtenbelt, Wouter D.

2016-01-01

Reviews on whole body human cold adaptation generally do not distinguish between population studies and dedicated acclimation studies, leading to confusing results. Population studies show that indigenous black Africans have reduced shivering thermogenesis in the cold and poor cold induced

Spectroscopy with cold and ultra-cold neutrons

Directory of Open Access Journals (Sweden)

Abele Hartmut

2015-01-01

Full Text Available We present two new types of spectroscopy methods for cold and ultra-cold neutrons. The first method, which uses the R×B drift effect to disperse charged particles in a uniformly curved magnetic field, allows to study neutron β-decay. We aim for a precision on the 10−4 level. The second method that we refer to as gravity resonance spectroscopy (GRS allows to test Newton’s gravity law at short distances. At the level of precision we are able to provide constraints on any possible gravity-like interaction. In particular, limits on dark energy chameleon fields are improved by several orders of magnitude.

Cold recovery during regasification of LNG part one: Cold utilization far from the regasification facility

International Nuclear Information System (INIS)

La Rocca, Vincenzo

2010-01-01

The paper deals with cold recovery during LNG regasification. The applications analyzed pertain to the use in deep freezing agro food industry and in space air conditioning facilities in commercial sector (Supermarkets and Hypermarkets) of cold recovered from the regasification process. A modular LNG regasification unit is proposed having the regasification capacity of 2 BCM/year of gas and it is based on use of a Power Cycle working with Ethane, this unit allows operation of cold energy transfer, contained in LNG to be regasified, in a range of temperatures suitable for multipurpose use of cold, reducing regasification process irreversibility. Some electric energy is produced by the Power Cycle, but the purpose of the modular unit is to deliver cold suitable for industrial and commercial use in the proper temperature range utilizing Carbon dioxide as secondary fluid to transfer cold from regasification site to far end users. The subject is divided in two papers: this paper deals with facilities delivering cold released during LNG regasification and related pipeline facilities to transfer cold at far end users while the other paper pertains to analysis of end users applications. Results of a detailed thermodynamic and economic analysis demonstrate the suitability of the proposal.

Bridgman growth and assessment of CdTe and CdZnTe using the accelerated crucible rotation technique

Energy Technology Data Exchange (ETDEWEB)

Capper, P.; Harris, J.E.; O' Keefe, E.; Jones, C.L.; Ard, C.K.; Mackett, P.; Dutton, D. (Philips Infrared Defence Components, Southampton (United Kingdom))

1993-01-30

The Bridgman growth process for CdTe has been extended by applying the accelerated crucible rotation technique (ACRT). Modelling using ACRT has been extended to the 50 mm diameter required to produce grains large enough to yield CdTe(and Cd[sub 0.96]Zn[sub 0.04]Te) slices suitable for use in liquid phase epitaxy of Cd[sub x]Hg[sub 1-x]Te (CMT) layers. Two regimes are identified: ACRT parameter combinations which give maximum fluid velocities and that which maintains stable Ekman flow. Growth of crystals shows that larger single crystal regions are obtained when the Ekman flow is stable. Effects of changing the ampoule base shape have also been investigated. Techniques have been developed to produce 20 mm x 30 mm substrates oriented oriented close to the (111) direction. Assessment of these samples has included IR transmission, IR microscopy, defect etching, X-ray topography and X-ray diffraction curve width measurements. Chemical analyses have been carried out to determine impurity levels and matrix element distributions. Good quality CMT epitaxial layers, as demonstrated by good surface topography, electrical data and chemical analyses, have been grown onto material produced in this study. (orig.).

Age and Ethnic Differences in Cold Weather and Contagion Theories of Colds and Flu

Science.gov (United States)

Sigelman, Carol K.

2012-01-01

Age and ethnic group differences in cold weather and contagion or germ theories of infectious disease were explored in two studies. A cold weather theory was frequently invoked to explain colds and to a lesser extent flu but became less prominent with age as children gained command of a germ theory of disease. Explanations of how contact with…

Cold knife cone biopsy

Science.gov (United States)

... biopsy; Pap smear - cone biopsy; HPV - cone biopsy; Human papilloma virus - cone biopsy; Cervix - cone biopsy; Colposcopy - cone biopsy Images Female reproductive anatomy Cold cone biopsy Cold cone removal References Baggish ...

Corium melt researches at VESTA test facility

Directory of Open Access Journals (Sweden)

Hwan Yeol Kim

2017-10-01

cold crucible using an induction heating technique.

Cold water injection nozzles

International Nuclear Information System (INIS)

Kura, Masaaki; Maeda, Masamitsu; Endo, Takio.

1979-01-01

Purpose: To inject cold water in a reactor without applying heat cycles to a reactor container and to the inner wall of a feedwater nozzle by securing a perforated plate at the outlet of the cold water injection nozzle. Constitution: A disc-like cap is secured to the final end of a return nozzle of a control rod drive. The cap prevents the flow of a high temperature water flowing downward in the reactor from entering into the nozzle. The cap is perforated with a plurality of bore holes for injecting cold water into the reactor. The cap is made to about 100 mm in thickness so that the cold water passing through the bore holes is heated by the heat conduction in the cap. Accordingly, the flow of high temperature water flowing downwardly in the reactor is inhibited by the cap from backward flowing into the nozzle. Moreover, the flow of the cold water in the nozzle is controlled and rectified when passed through the bore holes in the cap and then injected into the reactor. (Yoshino, Y.)

Development of cold neutron spectrometers

International Nuclear Information System (INIS)

Lee, Changhee; Lee, C. H.; So, J. Y.; Park, S.; Han, Y. S.; Cho, S. J.; Moon, M. K.; Choi, Y. H.; Sun, G. M.

2012-03-01

□ Cold Neutron Triple Axsis Spectrometer (Cold-TAS) Development Ο Fabrication and Installation of the Major Cold-TAS Components Ο Performance Test of the Cold-TAS □ Cold Neutron Time-of-Flight Spectrometer(DC-TOF) Development Ο Fabrication of the Major DC-TOF Components Ο Development DC-TOF Data Reduction Software □ Expected Contribution The two world-class inelastic neutron scattering instruments measure atomic or molecular scale dynamics of meV energy range. This unprecedented measurement capability in the country will enable domestic and international scientists to observe new phenomena in their materials research to obtain world class results. Especially those who work in the fields of magnetic properties of superconductors and multiferroics, molecular dynamics, etc. will get more benefit from these two instruments

Zirconium based bulk metallic glasses

International Nuclear Information System (INIS)

Dey, G.K.; Neogy, S.; Savalia, R.T.; Tewari, R.; Srivastava, D.; Banerjee, S.

2006-01-01

Metallic glasses have come into prominence in recent times because their nanocrystalline atomic arrangement imparts many useful and unusual properties to these metallic solids. In this study, bulk glasses have been obtained in Zr based multicomponent alloy by induction melting these alloys in silica crucibles and casting these in form of rods 3 and 6 mm in diameter in a copper mould

Cold perception and gene expression differ in Olea europaea seed coat and embryo during drupe cold acclimation.

Science.gov (United States)

D'Angeli, S; Falasca, G; Matteucci, M; Altamura, M M

2013-01-01

FAD2 and FAD7 desaturases are involved in cold acclimation of olive (Olea europaea) mesocarp. There is no research information available on cold acclimation of seeds during mesocarp cold acclimation or on differences in the cold response of the seed coat and embryo. How FAD2 and FAD7 affect seed coat and embryo cold responses is unknown. Osmotin positively affects cold acclimation in olive tree vegetative organs, but its role in the seeds requires investigation. OeFAD2.1, OeFAD2.2, OeFAD7 and Oeosmotin were investigated before and after mesocarp acclimation by transcriptomic, lipidomic and immunolabelling analyses, and cytosolic calcium concentration ([Ca(2+)](cyt)) signalling, F-actin changes and seed development were investigated by epifluorescence/histological analyses. Transient [Ca(2+)](cyt) rises and F-actin disassembly were found in cold-shocked protoplasts from the seed coat, but not from the embryo. The thickness of the outer endosperm cuticle increased during drupe exposure to lowering of temperature, whereas the embryo protoderm always lacked cuticle. OeFAD2 transcription increased in both the embryo and seed coat in the cold-acclimated drupe, but linoleic acid (i.e. the product of FAD2 activity) increased solely in the seed coat. Osmotin was immunodetected in the seed coat and endosperm of the cold-acclimated drupe, and not in the embryo. The results show cold responsiveness in the seed coat and cold tolerance in the embryo. We propose a role for the seed coat in maintaining embryo cold tolerance by increasing endosperm cutinization through FAD2 and osmotin activities. © 2012 The Authors. New Phytologist © 2012 New Phytologist Trust.

Cold fusion research

International Nuclear Information System (INIS)

1989-11-01

I am pleased to forward to you the Final Report of the Cold Fusion Panel. This report reviews the current status of cold fusion and includes major chapters on Calorimetry and Excess Heat, Fusion Products and Materials Characterization. In addition, the report makes a number of conclusions and recommendations, as requested by the Secretary of Energy

COLD-WORKED HARDWARE

Directory of Open Access Journals (Sweden)

N. M. Strizhak

2007-01-01

Full Text Available The different types of cold-worked accessory are examined in the article. The necessity of development of such type of accessory in the Republic of Belarus due to requirements of market is shown. High emphasis is placed on the methods of increase of plasticity of cold-worked accessory from usual mill of RUP and CIS countries.

Working in the Cold

Centers for Disease Control (CDC) Podcasts

During the winter, many workers are outdoors, working in cold, wet, icy, or snowy conditions. Learn how to identify symptoms that tell you there may be a problem and protect yourself from cold stress.

Major differences observed in transcript profiles of blueberry during cold acclimation under field and cold room conditions.

Science.gov (United States)

Dhanaraj, Anik L; Alkharouf, Nadim W; Beard, Hunter S; Chouikha, Imed B; Matthews, Benjamin F; Wei, Hui; Arora, Rajeev; Rowland, Lisa J

2007-02-01

Our laboratory has been working toward increasing our understanding of the genetic control of cold hardiness in blueberry (Vaccinium section Cyanococcus) to ultimately use this information to develop more cold hardy cultivars for the industry. Here, we report using cDNA microarrays to monitor changes in gene expression at multiple times during cold acclimation under field and cold room conditions. Microarrays contained over 2,500 cDNA inserts, approximately half of which had been picked and single-pass sequenced from each of two cDNA libraries that were constructed from cold acclimated floral buds and non-acclimated floral buds of the fairly cold hardy cv. Bluecrop (Vaccinium corymbosum L.). Two biological samples were examined at each time point. Microarray data were analyzed statistically using t tests, ANOVA, clustering algorithms, and online analytical processing (OLAP). Interestingly, more transcripts were found to be upregulated under cold room conditions than under field conditions. Many of the genes induced only under cold room conditions could be divided into three major types: (1) genes associated with stress tolerance; (2) those that encode glycolytic and TCA cycle enzymes, and (3) those associated with protein synthesis machinery. A few of the genes induced only under field conditions appear to be related to light stress. Possible explanations for these differences are discussed in physiological context. Although many similarities exist in how plants respond during cold acclimation in the cold room and in the field environment, there are major differences suggesting caution should be taken in interpreting results based only on artificial, cold room conditions.

Linear induction accelerators

International Nuclear Information System (INIS)

Briggs, R.J.

1986-06-01

The development of linear induction accelerators has been motivated by applications requiring high-pulsed currents of charged particles at voltages exceeding the capability of single-stage, diode-type accelerators and at currents too high for rf accelerators. In principle, one can accelerate charged particles to arbitrarily high voltages using a multi-stage induction machine, but the 50-MeV, 10-kA Advanced Test Accelerator (ATA) at LLNL is the highest voltage machine in existence at this time. The advent of magnetic pulse power systems makes sustained operation at high-repetition rates practical, and this capability for high-average power is very likely to open up many new applications of induction machines in the future. This paper surveys the US induction linac technology with primary emphasis on electron machines. A simplified description of how induction machines couple energy to the electron beam is given, to illustrate many of the general issues that bound the design space of induction linacs

Labor Induction

Science.gov (United States)

f AQ FREQUENTLY ASKED QUESTIONS FAQ154 LABOR, DELIVERY, AND POSTPARTUM CARE Labor Induction • What is labor induction? • Why is labor induced? • What is the Bishop score? • What is “ripening ...

Inductive reasoning 2.0.

Science.gov (United States)

Hayes, Brett K; Heit, Evan

2018-05-01

Inductive reasoning entails using existing knowledge to make predictions about novel cases. The first part of this review summarizes key inductive phenomena and critically evaluates theories of induction. We highlight recent theoretical advances, with a special emphasis on the structured statistical approach, the importance of sampling assumptions in Bayesian models, and connectionist modeling. A number of new research directions in this field are identified including comparisons of inductive and deductive reasoning, the identification of common core processes in induction and memory tasks and induction involving category uncertainty. The implications of induction research for areas as diverse as complex decision-making and fear generalization are discussed. This article is categorized under: Psychology > Reasoning and Decision Making Psychology > Learning. © 2017 Wiley Periodicals, Inc.

Effects of cold temperatures on the excitability of rat trigeminal ganglion neurons that are not for cold sensing.

Science.gov (United States)

Kanda, Hirosato; Gu, Jianguo G

2017-05-01

Aside from a small population of primary afferent neurons for sensing cold, which generate sensations of innocuous and noxious cold, it is generally believed that cold temperatures suppress the excitability of primary afferent neurons not responsible for cold sensing. These not-for-cold-sensing neurons include the majority of non-nociceptive and nociceptive afferent neurons. In this study we have found that the not-for-cold-sensing neurons of rat trigeminal ganglia (TG) change their excitability in several ways at cooling temperatures. In nearly 70% of not-for-cold-sensing TG neurons, a cooling temperature of 15°C increases their membrane excitability. We regard these neurons as cold-active neurons. For the remaining 30% of not-for-cold-sensing TG neurons, the cooling temperature of 15°C either has no effect (cold-ineffective neurons) or suppress their membrane excitability (cold-suppressive neurons). For cold-active neurons, the cold temperature of 15°C increases their excitability as is evidenced by increases in action potential (AP) firing numbers and/or the reduction in AP rheobase when these neurons are depolarized electrically. The cold temperature of 15°C significantly inhibits M-currents and increases membrane input resistance of cold-active neurons. Retigabine, an M-current activator, abolishes the effect of cold temperatures on AP firing, but not the effect of cold temperature on AP rheobase levels. The inhibition of M-currents and the increases of membrane input resistance are likely two mechanisms by which cooling temperatures increase the excitability of not-for-cold-sensing TG neurons. This article is part of the special article series "Pain". © 2015 International Society for Neurochemistry.

Impairment of exercise performance following cold water immersion is not attenuated after 7 days of cold acclimation.

Science.gov (United States)

Jones, Douglas M; Roelands, Bart; Bailey, Stephen P; Buono, Michael J; Meeusen, Romain

2018-03-19

It is well-documented that severe cold stress impairs exercise performance. Repeated immersion in cold water induces an insulative type of cold acclimation, wherein enhanced vasoconstriction leads to greater body heat retention, which may attenuate cold-induced exercise impairments. The purpose of this study, therefore, was to investigate changes in exercise performance during a 7-day insulative type of cold acclimation. Twelve healthy participants consisting of eight males and four females (mean ± SD age: 25.6 ± 5.2 years, height: 174.0 ± 8.9 cm, weight: 75.6 ± 13.1 kg) performed a 20 min self-paced cycling test in 23 °C, 40% humidity without prior cold exposure. Twenty-four hours later they began a 7-day cold acclimation protocol (daily 90 min immersion in 10 °C water). On days one, four, and seven of cold acclimation, participants completed the same cycling test. Measurements of work completed, core and skin temperatures, heart rate, skin blood flow, perceived exertion, and thermal sensation were measured during each cycling test. Successful insulative cold acclimation was observed. Work produced during the baseline cycling test (220 ± 70 kJ) was greater (p immersions (195 ± 58, 197 ± 60, and 194 ± 62 kJ) despite similar ratings of perceived exertion during each test, suggesting that cold exposure impaired cycling performance. This impairment, however, was not attenuated over the cold acclimation period. Results suggest that insulative cold acclimation does not attenuate impairments in exercise performance that were observed following acute cold water immersion.

Analysis of cold resistance and identification of SSR markers linked to cold resistance genes in Brassica rapa L.

Science.gov (United States)

Huang, Zhen; Zhang, Xuexian; Jiang, Shouhua; Qin, Mengfan; Zhao, Na; Lang, Lina; Liu, Yaping; Tian, Zhengshu; Liu, Xia; Wang, Yang; Zhang, Binbin; Xu, Aixia

2017-06-01

Currently, cold temperatures are one of the main factors threatening rapeseed production worldwide; thus, it is imperative to identify cold-resistant germplasm and to cultivate cold-resistant rapeseed varieties. In this study, the cold resistance of four Brassica rapa varieties was analyzed. The cold resistance of Longyou6 and Longyou7 was better than that of Tianyou2 and Tianyou4. Thus, an F 2 population derived from Longyou6 and Tianyou4 was used to study the correlation of cold resistance and physiological indexes. Our results showed that the degree of frost damage was related to the relative conductivity and MDA content (r1 = 0.558 and r2 = 0.447, respectively). In order to identify the markers related to cold resistance, 504 pairs of SSR (simple sequence repeats) primers were used to screen the two parents and F 2 population. Four and five SSR markers had highly significant positive correlation to relative conductivity and MDA, respectively. In addition, three of these SSR markers had a highly significant positive correlation to both of these two indexes. These three SSR markers were subsequently confirmed to be used to distinguish between cold-resistant and non-cold-resistant varieties. The results of this study will lay a solid foundation for the mapping of cold-resistant genes and molecular markers assisted selection for the cold-resistance.

Colds and the Flu

Science.gov (United States)

... disease (COPD). What medicines can I give my child? There is no cure for the cold or the flu, and antibiotics do not work against the viruses that cause colds and the flu. Pain relievers such as ...

Cold neutron interferometry and its application. 2. Coherency and cold neutron spin interferometry

International Nuclear Information System (INIS)

Achiwa, Norio; Ebisawa, Toru

1998-03-01

The second workshop entitled 'Interference studies and cold neutron spin interferometry' was held on 10 and 11 March 1998 at KUR (Kyoto University Research Reactor Institute, Kumatori). Cold neutron spin interferometry is a new field. So it is very important for its development to learn the studies of X-ray and neutron optics which are rapidly developing with long history. In the workshop, the issues related to interference were reviewed such as experimental studies on cold neutron spin interferometry, theoretical and experimental approach on tunneling time, interference experiments by neutrons and its application, interference studies using synchrotron radiation, topics on silicon interferometry and quantum measurement problem and cold neutron interference experiment related to quantum measurement problem. The 8 of the presented papers are indexed individually. (J.P.N.)

Cold moderators at ORNL

International Nuclear Information System (INIS)

Lucas, A. T.

1997-09-01

The Advanced Neutron Source (ANS) cold moderators were not an 'Oak Ridge first', but would have been the largest both physically and in terms of cold neutron flux. Two cold moderators were planned each 410 mm in diameter and containing about 30L of liquid deuterium. They were to be completely independent of each other. A modular system design was used to provide greater reliability and serviceability. When the ANS was terminated, upgrading of the resident High Flux Isotope Reactor (HFIR) was examined and an initial study was made into the feasibility of adding a cold source. Because the ANS design was modular, it was possible to use many identical design features. Sub-cooled liquid at 4 bar abs was initially chosen for the HFIR design concept, but this was subsequently changed to 15 bar abs to operate above the critical pressure. As in the ANS, the hydrogen will operate at a constant pressure throughout the temperature range and a completely closed loop with secondary containment was adopted. The heat load of 2 kW made the heat flux comparable with that of the ANS. Subsequent studies into the construction of cryogenic moderators for the proposed new Synchrotron Neutron source indicated that again many of the same design concepts could be used. By connecting the two cold sources together in series, the total heat load of 2 kW is very close to that of the HFIR allowing a very similar supercritical hydrogen system to be configured. The two hydrogen moderators of the SNS provide a comparable heat load to the HFIR moderator. It is subsequently planned to connect the two in series and operate from a single cold loop system, once again using supercritical hydrogen. The spallation source also provided an opportunity to re-examine a cold pellet solid methane moderator operating at 20K.

Determining the effect of grain size and maximum induction upon coercive field of electrical steels

Science.gov (United States)

Landgraf, Fernando José Gomes; da Silveira, João Ricardo Filipini; Rodrigues-Jr., Daniel

2011-10-01

Although theoretical models have already been proposed, experimental data is still lacking to quantify the influence of grain size upon coercivity of electrical steels. Some authors consider a linear inverse proportionality, while others suggest a square root inverse proportionality. Results also differ with regard to the slope of the reciprocal of grain size-coercive field relation for a given material. This paper discusses two aspects of the problem: the maximum induction used for determining coercive force and the possible effect of lurking variables such as the grain size distribution breadth and crystallographic texture. Electrical steel sheets containing 0.7% Si, 0.3% Al and 24 ppm C were cold-rolled and annealed in order to produce different grain sizes (ranging from 20 to 150 μm). Coercive field was measured along the rolling direction and found to depend linearly on reciprocal of grain size with a slope of approximately 0.9 (A/m)mm at 1.0 T induction. A general relation for coercive field as a function of grain size and maximum induction was established, yielding an average absolute error below 4%. Through measurement of B50 and image analysis of micrographs, the effects of crystallographic texture and grain size distribution breadth were qualitatively discussed.

Design of an induction linac driven CARM [Cyclotron Auto Resonance Maser] oscillator at 250 GHz

International Nuclear Information System (INIS)

Caplan, M.; Kulke, B.

1990-01-01

We present the design of a 250 GHz, 400 MW Cyclotron Auto Resonance Maser (CARM) oscillator driven by a 1 KA, 2 MeV electron beam produced by the induction linac at the ARC facility of LLNL. The oscillator circuit is designed as a feedback amplifier operating in the TE 11 mode at ten times cutoff terminated at each end with Bragg reflectors. Theory and cold test results are in good agreement for a manufactured Bragg reflector using 50 μm corrugations to ensure mode purity. The CARM is to be operational by February 1990. 3 figs., 2 tabs

IMPROVED, FAVORABLE FOR ENVIRONMENT POLYURETHANE COLD-BOX-PROCESS (COLD BOX «HUTTENES-ALBERTUS» .

Directory of Open Access Journals (Sweden)

A. Sergini

2005-01-01

Full Text Available The results of the laboratory and industrial investigations, the purpose of which is improvement of the classical Cold-box-process, i.e. the process of the slugs hardening in cold boxes, are presented.

Cold medicines and children

Science.gov (United States)

... ingredient. Avoid giving more than one OTC cold medicine to your child. It may cause an overdose with severe side ... the dosage instructions strictly while giving an OTC medicine to your child. When giving OTC cold medicines to your child: ...

On cold spots in tumor subvolumes

International Nuclear Information System (INIS)

Tome, Wolfgang A.; Fowler, Jack F.

2002-01-01

Losses in tumor control are estimated for cold spots of various 'sizes' and degrees of 'cold dose'. This question is important in the context of intensity modulated radiotherapy where differential dose-volume histograms (DVHs) for targets that abut a critical structure often exhibit a cold dose tail. This can be detrimental to tumor control probability (TCP) for fractions of cold volumes even as small as 1%, if the cold dose is lower than the prescribed dose by substantially more than 10%. The Niemierko-Goitein linear-quadratic algorithm with γ 50 slope 1-3 was used to study the effect of cold spots of various degrees (dose deficit below the prescription dose) and size (fractional volume of the cold dose). A two-bin model DVH has been constructed in which the cold dose bin is allowed to vary from a dose deficit of 1%-50% below prescription dose and to have volumes varying from 1% to 90%. In order to study and quantify the effect of a small volume of cold dose on TCP and effective uniform dose (EUD), a four-bin DVH model has been constructed in which the lowest dose bin, which has a fractional volume of 1%, is allowed to vary from 10% to 45% dose deficit below prescription dose. The highest dose bin represents a simultaneous boost. For fixed size of the cold spot the calculated values of TCP decreased rapidly with increasing degrees of cold dose for any size of the cold spot, even as small as 1% fractional volume. For the four-subvolume model, in which the highest dose bin has a fractional volume of 80% and is set at a boost dose of 10% above prescription dose, it is found that the loss in TCP and EUD is moderate as long as the cold 1% subvolume has a deficit less than approximately 20%. However, as the dose deficit in the 1% subvolume bin increases further it drives TCP and EUD rapidly down and can lead to a serious loss in TCP and EUD. Since a dose deficit to a 1% volume of the target that is larger than 20% of the prescription dose may lead to serious loss of

A transcription factor for cold sensation!

Directory of Open Access Journals (Sweden)

Milbrandt Jeffrey

2005-03-01

Full Text Available Abstract The ability to feel hot and cold is critical for animals and human beings to survive in the natural environment. Unlike other sensations, the physiology of cold sensation is mostly unknown. In the present study, we use genetically modified mice that do not express nerve growth factor-inducible B (NGFIB to investigate the possible role of NGFIB in cold sensation. We found that genetic deletion of NGFIB selectively affected behavioral responses to cold stimuli while behavioral responses to noxious heat or mechanical stimuli were normal. Furthermore, behavioral responses remained reduced or blocked in NGFIB knockout mice even after repetitive application of cold stimuli. Our results provide strong evidence that the first transcription factor NGFIB determines the ability of animals to respond to cold stimulation.

Development of metal-carbon eutectic cells for application as high temperature reference points in nuclear reactor severe accident tests: Results on the Fe-C, Co-C, Ti-C and Ru-C alloys' melting/freezing transformation temperature under electromagnetic induction heating

International Nuclear Information System (INIS)

Parga, Clemente J.; Journeau, Christophe; Parga, Clemente J.; Tokuhiro, Akira

2012-01-01

With the aim of reducing the high temperature measurement uncertainty of nuclear reactor severe accident experimental tests at the PLINIUS platform in Cadarache Research Centre, France, a variety of graphite cells containing a metal-carbon eutectic mix have been tested to assess the melting/freezing temperature reproducibility and their feasibility as calibration cells for thermometers. The eutectic cells have been thermally cycled in an induction furnace to assess the effect of heating/cooling rate, metal purity, graphite crucible design, and binary system constituents on the eutectic transformation temperature. A bi-chromatic pyrometer was used to perform temperature measurements in the graphite cell black cavity containing the metal-carbon eutectic mix. The eutectic points analyzed are all over 1100 C and cover an almost thousand degree span, i.e. from the Fe-Fe 3 C to the Ru-C eutectic. The induction heating permitted the attainment of heating and cooling rates of over 200 C/min under an inert atmosphere. The conducted tests allowed the determination of general trends and peculiarities of the solid. liquid transformation temperature under non-equilibrium and non-steady-state conditions of a variety of eutectic alloys (Fe-C, Co-C, Ti-C and Ru-C binary systems). (authors)

Determination of heat conductivity and thermal diffusivity of waste glass melter feed: Extension to high temperatures

International Nuclear Information System (INIS)

Rice, Jarrett A.; Pokorny, Richard; Schweiger, Michael J.; Hrma, Pavel R.

2014-01-01

The heat conductivity (λ) and the thermal diffusivity (a) of reacting glass batch, or melter feed, control the heat flux into and within the cold cap, a layer of reacting material floating on the pool of molten glass in an all-electric continuous waste glass melter. After previously estimating λ of melter feed at temperatures up to 680 deg C, we focus in this work on the λ(T) function at T > 680 deg C, at which the feed material becomes foamy. We used a customized experimental setup consisting of a large cylindrical crucible with an assembly of thermocouples, which monitored the evolution of the temperature field while the crucible with feed was heated at a constant rate from room temperature up to 1100°C. Approximating measured temperature profiles by polynomial functions, we used the heat transfer equation to estimate the λ(T) approximation function, which we subsequently optimized using the finite-volume method combined with least-squares analysis. The heat conductivity increased as the temperature increased until the feed began to expand into foam, at which point the conductivity dropped. It began to increase again as the foam turned into a bubble-free glass melt. We discuss the implications of this behavior for the mathematical modeling of the cold cap

Teacher induction

NARCIS (Netherlands)

Beijaard, D.; Buitink, J.; Kessels, C.; Peterson, P.; Baker, E.; McGraw, B.

2010-01-01

Teacher induction programs are intended to support the professional development of beginning teachers and thereby contribute to the reduction of teacher attrition during the early teaching years. Teacher induction programs are often based upon a deficit model with a focus on the better organization

Liquid metal cold trap

International Nuclear Information System (INIS)

Hundal, R.

1976-01-01

A cold trap assembly for removing impurities from a liquid metal is described. A hole between the incoming impure liquid metal and purified outgoing liquid metal acts as a continuous bleed means and thus prevents the accumulation of cover gases within the cold trap assembly

Cold-formed steel design

CERN Document Server

Yu, Wei-Wen

2010-01-01

The definitive text in the field, thoroughly updated and expanded Hailed by professionals around the world as the definitive text on the subject, Cold-Formed Steel Design is an indispensable resource for all who design for and work with cold-formed steel. No other book provides such exhaustive coverage of both the theory and practice of cold-formed steel construction. Updated and expanded to reflect all the important developments that have occurred in the field over the past decade, this Fourth Edition of the classic text provides you with more of the detailed, up-to-the-minute techni

Workshop on cold-blanket research

International Nuclear Information System (INIS)

1977-05-01

The objective of the workshop was to identify and discuss cold-plasma blanket systems. In order to minimize the bombardment of the walls by hot neutrals the plasma should be impermeable. This requires a density edge-thickness product of nΔ > 10 15 cm -2 . An impermeable cold plasma-gas blanket surrounding a hot plasma core reduces the plasma wall/limiter interaction. Accumulation of impurities in this blanket can be expected. Fuelling from a blanket may be possible as shown by experimental results, though not fully explained by classical transport of neutrals. Refuelling of a reacting plasma had to be ensured by inward diffusion. Experimental studies of a cold impermeable plasma have been done on the tokamak-like Ringboog device. Simulation calculations for the next generation of large tokamaks using a particular transport model, indicate that the plasma edge profile can be controlled to reduce the production of sputtered impurities to an acceptable level. Impurity control requires a small fraction of the radial space to accomodate the cold-plasma layer. The problem of exhaust is, however, more complicated. If the cold-blanket scheme works as predicted in the model calculations, then α-particles generated by fusion will be transported to the cold outside layer. The Communities' experimental programme of research has been discussed in terms of the tokamaks which are available and planned. Two options present themselves for the continuation of cold-blanket research

Catching a Cold When It's Warm

Science.gov (United States)

... Print this issue Catching a Cold When It’s Warm What’s the Deal with Summertime Sniffles? En español ... more unfair than catching a cold when it’s warm? How can cold symptoms arise when it’s not ...

Large reptiles and cold temperatures: Do extreme cold spells set distributional limits for tropical reptiles in Florida?

Science.gov (United States)

Mazzotti, Frank J.; Cherkiss, Michael S.; Parry, Mark; Beauchamp, Jeff; Rochford, Mike; Smith, Brian J.; Hart, Kristen M.; Brandt, Laura A.

2016-01-01

Distributional limits of many tropical species in Florida are ultimately determined by tolerance to low temperature. An unprecedented cold spell during 2–11 January 2010, in South Florida provided an opportunity to compare the responses of tropical American crocodiles with warm-temperate American alligators and to compare the responses of nonnative Burmese pythons with native warm-temperate snakes exposed to prolonged cold temperatures. After the January 2010 cold spell, a record number of American crocodiles (n = 151) and Burmese pythons (n = 36) were found dead. In contrast, no American alligators and no native snakes were found dead. American alligators and American crocodiles behaved differently during the cold spell. American alligators stopped basking and retreated to warmer water. American crocodiles apparently continued to bask during extreme cold temperatures resulting in lethal body temperatures. The mortality of Burmese pythons compared to the absence of mortality for native snakes suggests that the current population of Burmese pythons in the Everglades is less tolerant of cold temperatures than native snakes. Burmese pythons introduced from other parts of their native range may be more tolerant of cold temperatures. We documented the direct effects of cold temperatures on crocodiles and pythons; however, evidence of long-term effects of cold temperature on their populations within their established ranges remains lacking. Mortality of crocodiles and pythons outside of their current established range may be more important in setting distributional limits.

CERAMIC WASTE FORM DATA PACKAGE

Energy Technology Data Exchange (ETDEWEB)

Amoroso, J.; Marra, J.

2014-06-13

The purpose of this data package is to provide information about simulated crystalline waste forms that can be used to select an appropriate composition for a Cold Crucible Induction Melter (CCIM) proof of principle demonstration. Melt processing, viscosity, electrical conductivity, and thermal analysis information was collected to assess the ability of two potential candidate ceramic compositions to be processed in the Idaho National Laboratory (INL) CCIM and to guide processing parameters for the CCIM operation. Given uncertainties in the CCIM capabilities to reach certain temperatures throughout the system, one waste form designated 'Fe-MP' was designed towards enabling processing and another, designated 'CAF-5%TM-MP' was designed towards optimized microstructure. Melt processing studies confirmed both compositions could be poured from a crucible at 1600{degrees}C although the CAF-5%TM-MP composition froze before pouring was complete due to rapid crystallization (upon cooling). X-ray diffraction measurements confirmed the crystalline nature and phase assemblages of the compositions. The kinetics of melting and crystallization appeared to vary significantly between the compositions. Impedance spectroscopy results indicated the electrical conductivity is acceptable with respect to processing in the CCIM. The success of processing either ceramic composition will depend on the thermal profiles throughout the CCIM. In particular, the working temperature of the pour spout relative to the bulk melter which can approach 1700{degrees}C. The Fe-MP composition is recommended to demonstrate proof of principle for crystalline simulated waste forms considering the current configuration of INL's CCIM. If proposed modifications to the CCIM can maintain a nominal temperature of 1600{degrees}C throughout the melter, drain, and pour spout, then the CAF-5%TM-MP composition should be considered for a proof of principle demonstration.

Tip model of cold fission

International Nuclear Information System (INIS)

Goennenwein, F.; Boersig, B.

1991-01-01

Cold fission is defined to be the limiting case of nuclear fission where virtually all of the available energy is converted into the total kinetic energy of the fragments. The fragments have, therefore, to be born in or at least close to their respective ground states. Starting from the viewpoint that cold fission corresponds to most compact scission configurations, energy constraints have been exploited to calculate minimum tip distances between the two nascent fragments in binary fission. Crucial input parameters to this tip model of cold fission are the ground-state deformations of fragment nuclei. It is shown that the minimum tip distances being compatible with energy conservation vary strongly with both the mass and charge fragmentation of the fission prone nucleus. The tip distances refer to nuclei with equivalent sharp surfaces. In keeping with the size of the surface width of leptodermous nuclei, only configurations where the tip distances are smaller than a few fm may be considered as valid scission configurations. From a comparison with experimental data on cold fission this critical tip distance appears to be 3.0 fm for the model parameters chosen. Whenever the model calculation yields tip distances being smaller than the critical value, a necessary condition for attaining cold fission is considered to be fulfilled. It is shown that this criterion allows to understand in fair agreement with experiment which mass fragmentations are susceptible to lead to cold fission and which fragment-charge divisions are the most favored in each isobaric mass chain. Being based merely on energy arguments, the model cannot aim at predicting fragment yields in cold fission. However, the tip model proposed appears well suited to delineate the phase space where cold fission phenomena may come into sight. (orig.)

Surface characterization for high purity Fe-Cr alloys

International Nuclear Information System (INIS)

Iwai, H.; Oiwa, R.; Takaki, S.; Abiko, K.

1995-01-01

Fe-50mass%Cr was prepared in a cold crucible furnace with induction heating, then refined by floating-zone melting (FZM). The chemistries on the surface before and after FZM were compared by XPS measurement. C and O were observed on top surfaces both before and after as a hydrocarbon, carbonyl group and carboxyl group which are adsorbed chemical components. The other impurities were observed on the surface in both cases; however, the number and level of impurities on the surface after FZM were much larger than those on the surface before FZM; these adhered to the surface during sample preparation for XPS measurement. It is concluded that sample preparation introduces contamination which affects the detection limit of chemical analytical instruments. Sn was only observed on the top surface after FZM. It was segregated Sn which was contained in chromium as a starting material. It must be eliminated before starting. From XPS depth profiling results, it was concluded that 0.2 nm thickness of carbon such as hydrocarbon and organic components are adsorbed on the 1 nm thickness of oxide layer. Below the oxide layer, a lack of Cr was observed down to a depth of 6 nm. (orig.)

The preliminary results of steam explosion experiments in TROI

International Nuclear Information System (INIS)

Song, J.H.; Park, I.K.; Chang, Y.J.; Min, B.T.; Hong, S.W.; Kim, H.D.

2001-01-01

Korea Atomic Energy Research Institute (KAERI) launched an intermediate scale steam explosion experiment named 'Test for Real corium Interaction with water (TROI)' using reactor material to investigate the effect of material composition, multi-dimensional melt-water interaction, and hydrogen generation. The melt-water interaction is confined in a pressure vessel with the multi-dimensional fuel and water pool geometry. The cold crucible technology, where the mixture of oxide powder in a water-cooled cage is heated by high frequency induction, is employed. It minimizes unwanted inclusion of impurities during the melting process. The data acquisition system and instrumentations which measure the static and dynamic pressure, temperatures of melt and water are set up. In the first series of tests using several kg of ZrO 2 , melt water interaction is made in a heated water pool at 95 Celsius degrees without triggering. A steam spike pressure at about 10 bar is observed. The morphology of debris shows that there was a mild local steam explosion. The melt water interaction was monitored by video cameras. The UO 2 tests are scheduled around March of 2001, in parallel with the improvements of the design of test facility. (authors)

Cold moderators for pulsed neutron sources

International Nuclear Information System (INIS)

Carpenter, J.M.

1990-01-01

This paper reviews cold moderators in pulsed neutron sources and provides details of the performance of different cold moderator materials and configurations. Analytical forms are presented which describe wavelength spectra and emission time distributions. Several types of cooling arrangements used in pulsed source moderators are described. Choices of materials are surveyed. The author examines some of the radiation damage effects in cold moderators, including the phenomenon of ''burping'' in irradiated cold solid methane. 9 refs., 15 figs., 4 tabs

A transcription factor for cold sensation!

OpenAIRE

Kim, Susan J; Qu, Zhican; Milbrandt, Jeffrey; Zhuo, Min

2005-01-01

Abstract The ability to feel hot and cold is critical for animals and human beings to survive in the natural environment. Unlike other sensations, the physiology of cold sensation is mostly unknown. In the present study, we use genetically modified mice that do not express nerve growth factor-inducible B (NGFIB) to investigate the possible role of NGFIB in cold sensation. We found that genetic deletion of NGFIB selectively affected behavioral responses to cold stimuli while behavioral respons...

International workshop on cold neutron sources

Energy Technology Data Exchange (ETDEWEB)

Russell, G.J.; West, C.D. (comps.) (Los Alamos National Lab., NM (United States))

1991-08-01

The first meeting devoted to cold neutron sources was held at the Los Alamos National Laboratory on March 5--8, 1990. Cosponsored by Los Alamos and Oak Ridge National Laboratories, the meeting was organized as an International Workshop on Cold Neutron Sources and brought together experts in the field of cold-neutron-source design for reactors and spallation sources. Eighty-four people from seven countries attended. Because the meeting was the first of its kind in over forty years, much time was spent acquainting participants with past and planned activities at reactor and spallation facilities worldwide. As a result, the meeting had more of a conference flavor than one of a workshop. The general topics covered at the workshop included: Criteria for cold source design; neutronic predictions and performance; energy deposition and removal; engineering design, fabrication, and operation; material properties; radiation damage; instrumentation; safety; existing cold sources; and future cold sources.

International workshop on cold neutron sources

International Nuclear Information System (INIS)

Russell, G.J.; West, C.D.

1991-08-01

The first meeting devoted to cold neutron sources was held at the Los Alamos National Laboratory on March 5--8, 1990. Cosponsored by Los Alamos and Oak Ridge National Laboratories, the meeting was organized as an International Workshop on Cold Neutron Sources and brought together experts in the field of cold-neutron-source design for reactors and spallation sources. Eighty-four people from seven countries attended. Because the meeting was the first of its kind in over forty years, much time was spent acquainting participants with past and planned activities at reactor and spallation facilities worldwide. As a result, the meeting had more of a conference flavor than one of a workshop. The general topics covered at the workshop included: Criteria for cold source design; neutronic predictions and performance; energy deposition and removal; engineering design, fabrication, and operation; material properties; radiation damage; instrumentation; safety; existing cold sources; and future cold sources

Cold trap disposed within a tank

International Nuclear Information System (INIS)

Kanbe, Mitsuru.

1983-01-01

Purpose: To improve the reliability and the durability of cold traps by simplifying the structure and recycling liquid metals without using electromagnetic pumps. Constitution: The reactor container is partitioned by an intermediate container enhousing primary recycling pumps and cold traps. The inlet and the exit for the liquid metal of each cold trap are opened to the outside and the inside of the intermediate container respectively. In such a structure, the pressure difference between the inside and the outside of the intermediate container is exerted on the cold traps due to the exhaust pressure of the recycling pumps in which the liquid metal flowing into the cold traps is purified through filters, cooled and then discharged from the exit to the cold plenum. In this way, liquid metal can be recycled without using an electromagnetic pump whose reliability has not yet been established. (Kamimura, M.)

Cold War Paradigms and the Post-Cold War High School History Curriculum.

Science.gov (United States)

McAninch, Stuart A.

1995-01-01

Discusses how Cold War ideological models provide a way to examine the U.S. role in world affairs. Discusses and compares on the writings of Paul Gagnon and Noam Chomsky on this topic. Concludes that students should stand outside both models to develop a meaningful perspective on the U.S. role during the Cold War. (CFR)

Dence Cold Matter

Directory of Open Access Journals (Sweden)

Stavinskiy Alexey

2014-04-01

Full Text Available Possible way to create dense cold baryonic matter in the laboratory is discussed. The density of this matter is comparable or even larger than the density of neutron star core. The properties of this matter can be controlled by trigger conditions. Experimental program for the study of properties of dense cold matter for light and heavy ion collisions at initial energy range √sNN~2-3GeV is proposed..

Comparison on Promotion Effect of Various Types of Surfactants on HCFC-141b Hydrate Induction Time

Science.gov (United States)

Li, Juan; Sun, Zhigao; Liu, Chenggang; Zhu, Minggui

2018-03-01

Cold storage in air conditioning based on refrigerant hydrate is a new-type energy saving technology to reduce initial investment and running cost of air conditioning equipments and improve system stability. Refrigerant hydrate is generated under critical temperature and pressure condition, while surfactant is an effective medium to promote its phase equilibrium. In this paper, in order to research such promotion effect, different type of surfactants with unique mechanism, SDS, Tween80 and Span80, n-BA were selected to compare the respective impact on HCFC141b hydrate induction time based on temperature curve. Experimental results showed that no obvious change had been discovered when no surfactant was added into pure water system, which coincided with phase equilibrium diagram of HCFC141b. All the four kinds of surfactants had realized promotion effect to various degrees. For each hydration system, a large gap existed between the longest and the shortest induction time in 6 groups of parallel experiments, meaning relatively poor system stability. Under the combined effect of Tween80 (2wt%), Span80 (0.1wt%) and n-BA (0.1wt%), average and the shortest induction time was 20.9min and 17.5min respectively, corresponding to the best promotion effect.

Magnetic compound refractive lens for focusing and polarizing cold neutron beams

International Nuclear Information System (INIS)

Littrell, K. C.; Velthuis, S. G. E. te; Felcher, G. P.; Park, S.; Kirby, B. J.; Fitzsimmons, M. R.

2007-01-01

Biconcave cylindrical lenses are used to focus beams of x rays or neutrons using the refractive properties of matter. In the case of neutrons, the refractive properties of magnetic induction can similarly focus and simultaneously polarize the neutron beam without the concomitant attenuation of matter. This concept of a magnetic refractive lens was tested using a compound lens consisting of 99 pairs of cylindrical permanent magnets. The assembly successfully focused the intensity of a white beam of cold neutrons of one spin state at the detector, while defocusing the other. This experiment confirmed that a lens of this nature may boost the intensity locally by almost an order of magnitude and create a polarized beam. An estimate of the performance of a more practically dimensioned device suitable for incorporation in reflectometers and slit-geometry small angle scattering instruments is given

Magnetic compound refractive lens for focusing and polarizing cold neutron beams.

Science.gov (United States)

Littrell, K C; te Velthuis, S G E; Felcher, G P; Park, S; Kirby, B J; Fitzsimmons, M R

2007-03-01

Biconcave cylindrical lenses are used to focus beams of x rays or neutrons using the refractive properties of matter. In the case of neutrons, the refractive properties of magnetic induction can similarly focus and simultaneously polarize the neutron beam without the concomitant attenuation of matter. This concept of a magnetic refractive lens was tested using a compound lens consisting of 99 pairs of cylindrical permanent magnets. The assembly successfully focused the intensity of a white beam of cold neutrons of one spin state at the detector, while defocusing the other. This experiment confirmed that a lens of this nature may boost the intensity locally by almost an order of magnitude and create a polarized beam. An estimate of the performance of a more practically dimensioned device suitable for incorporation in reflectometers and slit-geometry small angle scattering instruments is given.

Způsoby vitrifikace vysoceaktivních odpadů, vznikajících při přepracování vyhořelého jaderného paliva

OpenAIRE

Machová, Pavlína

2011-01-01

This thesis summarizes the general concepts regarding the High-level waste vitrification. It describes the one-stage and two-stage principles of vitrification and special method "cold crucible". There are summarized advantages and disadvantages of these methods. In this thesis are specific of vitrification facilities around the world. There are the general characteristics of glass used for immobilization High- level waste. Most countries use borosilicate glass, but only in Russia are used pho...

Induction heating using induction coils in series-parallel circuits

Science.gov (United States)

Matsen, Marc Rollo; Geren, William Preston; Miller, Robert James; Negley, Mark Alan; Dykstra, William Chet

2017-11-14

A part is inductively heated by multiple, self-regulating induction coil circuits having susceptors, coupled together in parallel and in series with an AC power supply. Each of the circuits includes a tuning capacitor that tunes the circuit to resonate at the frequency of AC power supply.

Body temperature and cold sensation during and following exercise under temperate room conditions in cold-sensitive young trained females.

Science.gov (United States)

Fujii, Naoto; Aoki-Murakami, Erii; Tsuji, Bun; Kenny, Glen P; Nagashima, Kei; Kondo, Narihiko; Nishiyasu, Takeshi

2017-11-01

We evaluated cold sensation at rest and in response to exercise-induced changes in core and skin temperatures in cold-sensitive exercise trained females. Fifty-eight trained young females were screened by a questionnaire, selecting cold-sensitive (Cold-sensitive, n  = 7) and non-cold-sensitive (Control, n  = 7) individuals. Participants rested in a room at 29.5°C for ~100 min after which ambient temperature was reduced to 23.5°C where they remained resting for 60 min. Participants then performed 30-min of moderate intensity cycling (50% peak oxygen uptake) followed by a 60-min recovery. Core and mean skin temperatures and cold sensation over the whole-body and extremities (fingers and toes) were assessed throughout. Resting core temperature was lower in the Cold-sensitive relative to Control group (36.4 ± 0.3 vs. 36.7 ± 0.2°C). Core temperature increased to similar levels at end-exercise (~37.2°C) and gradually returned to near preexercise rest levels at the end of recovery (>36.6°C). Whole-body cold sensation was greater in the Cold-sensitive relative to Control group during resting at a room temperature of 23.5°C only without a difference in mean skin temperature between groups. In contrast, cold sensation of the extremities was greater in the Cold-sensitive group prior to, during and following exercise albeit this was not paralleled by differences in mean extremity skin temperature. We show that young trained females who are sensitive to cold exhibit augmented whole-body cold sensation during rest under temperate ambient conditions. However, this response is diminished during and following exercise. In contrast, cold sensation of extremities is augmented during resting that persists during and following exercise. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

Application of forgetful analgesia induction in induction period in patients with obstructive jaundice

Directory of Open Access Journals (Sweden)

Wei DU

2014-03-01

Full Text Available Objective　To observe the effect of forgetful analgesia induction and tracheal intubation on the hemodynamic changes in induction period in patients with obstructive jaundice, and explore a safe method for anesthesia induction and tracheal intubation. Methods　Sixty patients with obstructive jaundice undergoing elective abdominal operation in General Hospital of PLA from February, 2013 to August, 2013 were involved in the present study. Participants included 36 male and 24 female patients, aging 19-65 years (mean 42±5 years, weighing 47-73 kg (mean 54±6 kg, with ASA Ⅰ-Ⅱ. These 60 patients were randomly divided into forgetful analgesia induction-tracheal intubation group (group A, n=30 and rapid induction-tracheal intubation group (group B, n=30. The heart rate (HR, mean arterial pressure (MAP, pulse oxygen saturation (SpO2 at the time point of before induction (T0, before intubation (T1, at the moment of intubation (T2 and 3 min after intubation (T3 were determined in both groups. Administration times of ephedrine hydrochloride and atropine was recorded in both groups. Results　There was no significant difference in HR, MAP, SpO2 before and after induction in group A. In the patients of group B, the HR increased and MAP decreased after induction compared with those before induction (P<0.05, and the change of SpO2 was not significant. Ephedrine hydrochloride and atropine were administrated in both groups, and the cases and times of ephedrine hydrochloride administration were more in group B than in group A (P<0.05. Conclusion　The forgetful analgesia induction-tracheal intubation could effectively control the stress response and reduce the fluctuation in hemodynamics during induction of anesthesia in patients with obstructive jaundice. DOI: 10.11855/j.issn.0577-7402.2014.02.15

Final Report for Crucible -Scale Radioactive Vitrification and Product Test of Waste Envelope B (AZ-102) Low-Activity Waste Glass

International Nuclear Information System (INIS)

CRAWFORD, CHARLES

2004-01-01

A proof-of-technology demonstration for the Hanford River Protection Project (RPP) Waste treatment and Immobilization Plant (WTP) was performed by the Savannah River Technology Center (SRTC). As part of this demonstration, treated AZ-102 Low-Activity Waste supernate was vitrified using a crucible-scale furnace. Initial glass samples were quench-cooled and characterized for metals and radionuclides. The glass was also durability tested using the American Society for Testing and Materials (ASTM) Product Consistency Test (PCT) protocol. These tests used the AZ-102 glass formulation Low Activity Waste (LAW) B88 that targeted AZ-102 waste loading at 5 wt% Na2O. After these initial results were obtained with the quench-cooled LAWB88 glass, a prototypical container centerline cooling (CCC) program was supplied to SRTC by WTP. A portion of the quench-cooled LAWB88 glass was remelted and centerline cooled. Samples from the CCC low-activity AZ-102 glass waste form were durability tested using the PCT and characterized for crystalline phase identification.This final report documents the characterization and durability of this AZ-102 glass

Imaging with cold neutrons

International Nuclear Information System (INIS)

Lehmann, E.H.; Kaestner, A.; Josic, L.; Hartmann, S.; Mannes, D.

2011-01-01

Neutrons for imaging purposes are provided mainly from thermal beam lines at suitable facilities around the world. The access to cold neutrons is presently limited to very few places only. However, many challenging options for imaging with cold neutrons have been found out, given by the interaction behavior of the observed materials with neutrons in the cold energy range (3-10 A). For absorbing materials, the interaction probability increases proportionally with the wavelength with the consequence of more contrast but less transmission with cold neutrons. Many materials are predominantly scattering neutrons, in particular most of crystalline structural materials. In these cases, cold neutrons play an important role by covering the energy range of the most important Bragg edges given by the lattice planes of the crystallites. This particular behavior can be used for at least two important aspects-choosing the right energy of the initial beam enables to have a material more or less transparent, and a direct macroscopic visualization of the crystalline structure and its change in a manufacturing process. Since 2006, PSI operates its second beam line for neutron imaging, where cold neutrons are provided from a liquid deuterium cold source (operated at 25 K). It has been designed to cover the most current aspects in neutron imaging research with the help of high flexibility. This has been done with changeable inlet apertures, a turbine based velocity selector, two beam positions and variable detector systems, satisfying the demands of the individual investigation. The most important detection system was found to be a micro-tomography system that enables studies in the presently best spatial resolution. In this case, the high contrast from the sample interaction process and the high detection probability for the cold neutrons combines in an ideal combination for the best possible performance. Recently, it was found out that the energy selective studies might become a

Cold-water acclimation does not modify whole-body fluid regulation during subsequent cold-water immersion.

Science.gov (United States)

Stocks, J M; Patterson, M J; Hyde, D E; Jenkins, A B; Mittleman, K D; Taylor, N A S

2004-06-01

We investigated the impact of cold-water acclimation on whole-body fluid regulation using tracer-dilution methods to differentiate between the intracellular and extracellular fluid compartments. Seven euhydrated males [age 24.7 (8.7) years, mass 74.4 (6.4) kg, height 176.8 (7.8) cm, sum of eight skinfolds 107.4 (20.4) mm; mean (SD)] participated in a 14-day cold-water acclimation protocol, with 60-min resting cold-water stress tests [CWST; 18.1 (0.1) degrees C] on days 1, 8 and 15, and 90-min resting cold-water immersions [18.4 (0.4) degrees C] on intervening days. Subjects were immersed to the 4th intercostal space. Intracellular and extracellular fluid compartments, and plasma protein, electrolyte and hormone concentrations were investigated. During the first CWST, the intracellular fluid (5.5%) and plasma volumes were reduced (6.1%), while the interstitial fluid volume was simultaneously expanded (5.4%). This pattern was replicated on days 8 and 15, but did not differ significantly among test days. Acclimation did not produce significant changes in the pre-immersion distribution of total body water, or changes in plasma osmolality, total protein, electrolyte, atrial natriuretic peptide or aldosterone concentrations. Furthermore, a 14-day cold-water acclimation regimen did not elicit significant changes in body-fluid distribution, urine production, or the concentrations of plasma protein, electrolytes or the fluid-regulatory hormones. While acclimation trends were not evident, we have confirmed that fluid from extravascular cells is displaced into the interstitium during acute cold-water immersion, both before and after cold acclimation.

Molecular analysis of the role of osmolyte transporters opuCA and betL in Listeria monocytogenes after cold and freezing stress.

Science.gov (United States)

Miladi, Hanene; Elabed, Hamouda; Ben Slama, Rihab; Rhim, Amel; Bakhrouf, Amina

2017-03-01

Listeria monocytogenes is a food-borne pathogen of humans and other animals. The striking ability to survive several stresses usually used for food preservation makes L. monocytogenes one of the biggest concerns to the food industry. This ubiquity can be partly explained by the ability of the organism to grow and persist at very low temperatures, a consequence of its ability to accumulate cryoprotective compound called osmolytes. A quantitative RT-PCR assay was used to measure mRNA transcript accumulation for the stress response genes opuCA and betL (encoding carnitine and betaine transporters, respectively) and the housekeeping gene 16S rRNA. Assays were conducted on mid-exponential phase L. monocytogenes cells exposed to conditions reflecting cold and freezing stress, conditions usually used to preserve foods. We showed that expression of the two cold-adapted genes encoded the transporters of the cryoprotectants carnitine and betaine in ATCC 19115 and the food-isolated L. monocytogenes S1 is induced after cold and freezing stress exposure. Furthermore, transcriptional analysis of the genes encoding opuCA and betL revealed that each transporter is induced to different degrees upon cold shock of L. monocytogenes ATCC 19115 and S1. Our results confirm an increase in carnitine uptake at low temperatures more than in betaine after cold-shocked temperature compared to the non-stress control treatment. It was concluded the use of carnitine and betaine as cryoprotectants is essential for rapid induction of the tested stress response under conditions typically encountered during food preservation.

Postexercise cold water immersion modulates skeletal muscle PGC-1α mRNA expression in immersed and nonimmersed limbs: evidence of systemic regulation.

Science.gov (United States)

Allan, Robert; Sharples, Adam P; Close, Graeme L; Drust, Barry; Shepherd, Sam O; Dutton, John; Morton, James P; Gregson, Warren

2017-08-01

Mechanisms mediating postexercise cold-induced increases in PGC-1α gene expression in human skeletal muscle are yet to be fully elucidated but may involve local cooling effects on AMPK and p38 MAPK-related signaling and/or increased systemic β-adrenergic stimulation. Therefore, we aimed to examine whether postexercise cold water immersion enhancement of PGC-1α mRNA is mediated through local or systemic mechanisms. Ten subjects completed acute cycling (8 × 5 min at ~80% peak power output) followed by seated-rest (CON) or single-leg cold water immersion (CWI; 10 min, 8°C). Muscle biopsies were obtained preexercise, postexercise, and 3 h postexercise from a single limb in the CON condition but from both limbs in CWI [thereby providing tissue from a CWI and nonimmersed limb (NOT)]. Muscle temperature decreased up to 2 h postexercise following CWI (-5°C) in the immersed limb, with lesser changes observed in CON and NOT (-3°C, P cold induction of PGC-1α mRNA. NEW & NOTEWORTHY We report for the first time that postexercise cold water immersion of one limb also enhances PGC-1α expression in a contralateral, nonimmersed limb. We suggest that increased systemic β-adrenergic stimulation, and not localized cooling per se, exerts regulatory effects on local signaling cascades, thereby modulating PGC-1α expression. Therefore, these data have important implications for research designs that adopt contralateral, nonimmersed limbs as a control condition while also increasing our understanding of the potential mechanisms underpinning cold-mediated PGC-1α responses. Copyright © 2017 the American Physiological Society.

The molecular and cellular basis of cold sensation.

Science.gov (United States)

McKemy, David D

2013-02-20

Of somatosensory modalities, cold is one of the more ambiguous percepts, evoking the pleasant sensation of cooling, the stinging bite of cold pain, and welcome relief from chronic pain. Moreover, unlike the precipitous thermal thresholds for heat activation of thermosensitive afferent neurons, thresholds for cold fibers are across a range of cool to cold temperatures that spans over 30 °C. Until recently, how cold produces this myriad of biological effects has been poorly studied, yet new advances in our understanding of cold mechanisms may portend a better understanding of sensory perception as well as provide novel therapeutic approaches. Chief among these was the identification of a number of ion channels that either serve as the initial detectors of cold as a stimulus in the peripheral nervous system, or are part of rather sophisticated differential expression patterns of channels that conduct electrical signals, thereby endowing select neurons with properties that are amenable to electrical signaling in the cold. This review highlights the current understanding of the channels involved in cold transduction as well as presents a hypothetical model to account for the broad range of cold thermal thresholds and distinct functions of cold fibers in perception, pain, and analgesia.

Frequent extreme cold exposure and brown fat and cold-induced thermogenesis: A study in a monozygotic twin

NARCIS (Netherlands)

M.J. Vosselman (Maarten J.); G.H.E.J. Vijgen (Guy H. E. J.); B.R.M. Kingma (Boris R. M.); B. Brans (Boudewijn); W.D. Van Marken Lichtenbelt (Wouter D.)

2014-01-01

textabstractIntroduction: Mild cold acclimation is known to increase brown adipose tissue (BAT) activity and cold-induced thermogenesis (CIT) in humans. We here tested the effect of a lifestyle with frequent exposure to extreme cold on BAT and CIT in a Dutch man known as 'the Iceman', who has

Finger cold-induced vasodilation of older Korean female divers, haenyeo: effects of chronic cold exposure and aging

Science.gov (United States)

Lee, Joo-Young; Park, Joonhee; Koh, Eunsook; Cha, Seongwon

2017-07-01

The aim of the present study was to evaluate the local cold tolerance of older Korean female divers, haenyeo ( N = 22) in terms of cold acclimatization and ageing. As control groups, older non-diving females ( N = 25) and young females from a rural area ( N = 15) and an urban area ( N = 51) participated in this study. To evaluate local cold tolerance, finger cold-induced vasodilation (CIVD) during finger immersion of 4 °C water was examined. As a result, older haenyeos showed greater minimum finger temperature and recovery finger temperature than older non-diving females ( P < 0.05), but similar responses in onset time, peak time, maximum finger temperature, frequency of CIVD, heart rate, blood pressure, and thermal and pain sensations as those of older non-diving females. Another novel finding was that young urban females showed more vulnerable responses to local cold in CIVD variables and subjective sensations when compared to older females, whereas young rural females had the most excellent cold tolerance in terms of maximum temperature and frequency of CIVD among the four groups ( P < 0.05). The present results imply that older haenyeos still retain cold acclimatized features on the periphery even though they changed their cotton diving suits to wet suits in the early 1980s. However, cardiovascular responses and subjective sensations to cold reflect aging effects. In addition, we suggest that young people who have been adapted to highly insulated clothing and indoor heating systems in winter should be distinguished from young people who were exposed to less modern conveniences when compared to the aged in terms of cold tolerance.

Beam transport study of kA-class on the induction linac

Energy Technology Data Exchange (ETDEWEB)

Morimoto, Iwao; Zheng, Xiaodong; Maebara, Sunao; Shiho, Makoto [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Kishiro, Jun-ichi; Takayama, Ken [High Energy Accelerator Research Organization, Tsukuba, Ibaraki (Japan)

2000-02-01

Beam transport of kA-class for GW-class Free Electron Laser (FEL) was carried out through the two induction linacs (JLA). The first 1 MV induction linac was used as an electron beam generator, in which a carbon-cloth impregnated cold cathode was equipped and 1 MV, 160ns pulsed high voltage was immersed. About 1 kA high current electron beam was successfully generated and accelerated more 1 MeV by employing the following second induction linac. For kA-class high current beam generation and transportation, the most serious problem arises from the so strong space charge effect that the investigations to cure this effect both in the beam generation and the transportation are required. High rate beam loss comes from the strong space charge effect because the effect causes the unexpected beam blow up during the transportation. In the electron generator, the generated beam emittance was minimized with the program EGUN by choosing the geometry and shape of the cathode and anode electrode. In the beam transportation, a simulation program which included the space charge effect was developed. The simulation program was used to minimize and optimize the beam envelope oscillation through the beam transport line, and designed the configuration of the solenoid magnet channel. Experimentally, the electron beam of 450 A was extracted. The beam transport efficiency (beam current at outlet of accelerator/at inlet) reached to 90%, under the magnetic field of 1 kG. It was succeeded that the electron beam of 2 MeV - 400 A was transported with the mean beam diameter of 50 mm. (author)

Compaction of irradiated fuel can wastes by high temperature melting in cold crucibles

International Nuclear Information System (INIS)

Piccinato, R.; Ruty, J.P.; Caraballo, R.; Jacquet-Francillon, N.

1993-01-01

The fusion of hull wastes obtained from the reprocessing of various irradiated fuels is an alternative method to the cementation process used for the conditioning of such wastes. This new process, based on the direct fusion of hulls, has been carried out at CEA Marcoule with an inactive industrial prototype and qualified with an active laboratory prototype. The report shows the results obtained with the lab prototype on stainless steel and zircaloy hulls

Use of ATG-Fresenius as an Induction Agent in Deceased-Donor Kidney Transplantation.

Science.gov (United States)

Yilmaz, M; Sezer, T Ö; Kir, O; Öztürk, A; Hoşcoşkun, C; Töz, H

2017-04-01

Anti-T-lymphocyte globulins (ATG) are most commonly used as induction agents in kidney transplantation (KT). In this study, we investigated the use of ATG as induction therapy in deceased-donor KT. Among 152 deceased-donor KT recipients transplanted between January 2009 and December 2003, 147 with exact data were enrolled in this study. Delayed graft function was defined as dialysis requirement after KT. Greater than 10% panel-reactive antibody (PRA) was considered as positive. Total ATG (rATG-Fresenius) dosage and induction duration was evaluated. Mean age was 45 ± 10 years; 91 patients were male and 56 patients were female. Class I and class II PRA-positive patient numbers were 20 (13.6%) and 17 (11.5%), respectively. Pre-transplant dialysis vintage was 108 ± 63 months. Mean donor age was 42 ± 17, and cold ischemia time was 16 ± 5 hours. Eighty-nine patients (60%) had delayed graft function and needed at least one session of hemodialysis after transplantation. Cumulative ATG-F dosage was 676 ± 274 mg. The mean ATG-F cumulative dosage was 10.6 ± 3.8 mg/kg. At the end of first year, mean creatinine and proteinuria levels were 1.4 ± 1.0 mg/dL and 0.3 ± 0.4 g/d, respectively. Mean follow-up time was 32 ± 20 months. During follow-up, there were 14 graft failures and 11 patients died. Patient survival for 1 and 2 years were 93% and 92.3%, respectively. Death-censored graft survival rates for 1 and 2 years were 94.8% and 90.8%, respectively. ATG-F induction provides acceptable graft and patient survival in deceased-donor KT. ATG-F infusion is well tolerated. Infection rates seem to be acceptable compared with all transplantation populations. Copyright © 2017 Elsevier Inc. All rights reserved.

Working in the Cold

Centers for Disease Control (CDC) Podcasts

2016-02-08

During the winter, many workers are outdoors, working in cold, wet, icy, or snowy conditions. Learn how to identify symptoms that tell you there may be a problem and protect yourself from cold stress.  Created: 2/8/2016 by National Institute for Occupational Safety and Health (NIOSH).   Date Released: 2/8/2016.

Brown adipose tissue (BAT specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation

Directory of Open Access Journals (Sweden)

Juliane Weiner

2017-06-01

Full Text Available Objective: Several studies have demonstrated anti-diabetic and anti-obesogenic properties of visceral adipose tissue-derived serine protease inhibitor (vaspin and so evoked its potential use for treatment of obesity-related diseases. The aim of the study was to unravel physiological regulators of vaspin expression and secretion with a particular focus on its role in brown adipose tissue (BAT biology. Methods: We analyzed the effects of obesogenic diets and cold exposure on vaspin expression in liver and white and brown adipose tissue (AT and plasma levels. Vaspin expression was analyzed in isolated white and brown adipocytes during adipogenesis and in response to adrenergic stimuli. DNA-methylation within the vaspin promoter was analyzed to investigate acute epigenetic changes after cold-exposure in BAT. Results: Our results demonstrate a strong induction of vaspin mRNA and protein expression specifically in BAT of both cold-exposed and high-fat (HF or high-sugar (HS fed mice. While obesogenic diets also upregulated hepatic vaspin mRNA levels, cold exposure tended to increase vaspin gene expression of inguinal white adipose tissue (iWAT depots. Concomitantly, vaspin plasma levels were decreased upon obesogenic or thermogenic triggers. Vaspin expression was increased during adipogenesis but unaffected by sympathetic activation in brown adipocytes. Analysis of vaspin promoter methylation in AT revealed lowest methylation levels in BAT, which were acutely reduced after cold exposure. Conclusions: Our data demonstrate a novel BAT-specific regulation of vaspin gene expression upon physiological stimuli in vivo with acute epigenetic changes that may contribute to cold-induced expression in BAT. We conclude that these findings indicate functional relevance and potentially beneficial effects of vaspin in BAT function. Keywords: Brown adipose tissue, Browning, Cold exposure, DNA methylation, High-fat diet, High-sucrose diet, SerpinA12, Thermogenesis

Herpes Simplex Virus (Cold Sores)

Science.gov (United States)

... Print Share Cold Sores in Children: About the Herpes Simplex Virus Page Content ​A child's toddler and ... Cold sores (also called fever blisters or oral herpes) start as small blisters that form around the ...

Detection of DNA damage induced in vivo by a cross-linking agent with a circular channel crucible oscillating viscometer.

Science.gov (United States)

Balbi, C; Abelmoschi, M L; Roner, R; Giaretti, W; Parodi, S; Santi, L

1985-11-01

DNA damage induced in vivo by the cross-linking agent mitomycin C (MMC) was investigated with a new oscillating crucible viscometer. Viscosity was measured by lysing rat liver nuclei in an alkaline lysing solution (pH 12.5; 25 degrees C). In control samples the viscosity increased very slowly with time, reaching a plateau only after 10-12 h. The process was accelerated and the maximum viscosity was decreased by alkaline single-stranded breaks arising from methylation and subsequent depurination of DNA in vitro with dimethylsulphate (DMS). MMC, when given alone, had no evident effect on the time needed for reaching plateau viscosity but it induced a small increase in maximum viscosity. When MMC was given in association with DMS, the time of disentanglement remained unchanged (accelerated) but maximum viscosity was increased in a dose dependent way. We conclude that these data clearly confirm that the slow steady increase of the viscosity of control DNA with time reflects mainly the process of unwinding of the two strands. The speed of this process seems to depend only from the number of unwinding points in DNA (breaks).

Flu and Colds: In Depth

Science.gov (United States)

... to prevent colds or relieve cold symptoms. Andrographis (Andrographis paniculata) Chinese herbal medicines Green tea Guided imagery Hydrotherapy ... measurements (VAS) to assess the effectiveness of standardized Andrographis paniculata extract SHA-10 in reducing the symptoms of ...

Evaporative cooling enhanced cold storage system

Science.gov (United States)

Carr, P.

1991-10-15

The invention provides an evaporatively enhanced cold storage system wherein a warm air stream is cooled and the cooled air stream is thereafter passed into contact with a cold storage unit. Moisture is added to the cooled air stream prior to or during contact of the cooled air stream with the cold storage unit to effect enhanced cooling of the cold storage unit due to evaporation of all or a portion of the added moisture. Preferably at least a portion of the added moisture comprises water condensed during the cooling of the warm air stream. 3 figures.

Review on Cold-Formed Steel Connections

Science.gov (United States)

Tan, Cher Siang; Mohammad, Shahrin; Md Tahir, Mahmood; Shek, Poi Ngian

2014-01-01

The concept of cold-formed light steel framing construction has been widespread after understanding its structural characteristics with massive research works over the years. Connection serves as one of the important elements for light steel framing in order to achieve its structural stability. Compared to hot-rolled steel sections, cold-formed steel connections perform dissimilarity due to the thin-walled behaviour. This paper aims to review current researches on cold-formed steel connections, particularly for screw connections, storage rack connections, welded connections, and bolted connections. The performance of these connections in the design of cold-formed steel structures is discussed. PMID:24688448

Chlorophyll fluorescence emission can screen cold tolerance of cold acclimated Arabidopsis thaliana accessions

Czech Academy of Sciences Publication Activity Database

Mishra, Anamika; Heyer, A. G.; Mishra, Kumud

2014-01-01

Roč. 10, č. 38 (2014) ISSN 1746-4811 R&D Projects: GA MŠk EE2.3.20.0246; GA MŠk 7E12047 Institutional support: RVO:67179843 Keywords : high-throughput screening * chlorophyll a fluorescence transients * cold tolerance * cold acclimation * whole plant * Arabidopsis thaliana Subject RIV: EH - Ecology, Behaviour Impact factor: 3.102, year: 2014

Inductance loop and partial

CERN Document Server

Paul, Clayton R

2010-01-01

"Inductance is an unprecedented text, thoroughly discussing "loop" inductance as well as the increasingly important "partial" inductance. These concepts and their proper calculation are crucial in designing modern high-speed digital systems. World-renowned leader in electromagnetics Clayton Paul provides the knowledge and tools necessary to understand and calculate inductance." "With the present and increasing emphasis on high-speed digital systems and high-frequency analog systems, it is imperative that system designers develop an intimate understanding of the concepts and methods in this book. Inductance is a much-needed textbook designed for senior and graduate-level engineering students, as well as a hands-on guide for working engineers and professionals engaged in the design of high-speed digital and high-frequency analog systems."--Jacket.

Steel weldability. Underbead cold cracking

International Nuclear Information System (INIS)

Marquet, F.; Defourny, J.; Bragard, A.

1977-01-01

The problem of underbead cold cracking has been studied by the implant technique. This approach allows to take into account in a quantitative manner the different factors acting on the cold cracking phenomenon: structure under the weld bead, level of restraint, hydrogen content in the molten metal. The influence of the metallurgical factors depending from the chemical composition of the steel has been examined. It appeared that carbon equivalent is an important factor to explain cold cracking sensitivity but that it is not sufficient to characterize the steel. The results have shown that vanadium may have a deleterious effect on the resistance to cold cracking when the hydrogen content is high and that small silicon additions are beneficient. The influence of the diffusible hydrogen content has been checked and the important action of pre- and postheating has been shown. These treatments allow the hydrogen to escape from the weld before the metal has been damaged. Some inclusions (sulphides) may also decrease the influence of hydrogen. A method based on the implant tests has been proposed which allows to choose and to control safe welding conditions regarding cold cracking

Study of various evaporation rates of the mixture of Alq{sub 3}: DCM in a single furnace crucible

Energy Technology Data Exchange (ETDEWEB)

Abedi, Zahra; Janghouri, Mohammad [Laser and Plasma Research Institute, Shahid Beheshti University, G.C., Tehran 1983963113 (Iran, Islamic Republic of); Mohajerani, Ezeddin, E-mail: e-mohajerani@sbu.ac.ir [Laser and Plasma Research Institute, Shahid Beheshti University, G.C., Tehran 1983963113 (Iran, Islamic Republic of); Alahbakhshi, Masoud; Azari, Amin [Laser and Plasma Research Institute, Shahid Beheshti University, G.C., Tehran 1983963113 (Iran, Islamic Republic of); Fallahi, Afsoon [Department of Polymer Engineering and Color Technology, Amirkabir University of Technology, 424 Hafez Avenue, P.O. Box 15875-4413, Tehran (Iran, Islamic Republic of)

2014-03-15

The emitting color for a new organic light emitting diode (OLED) structure is tuned by doping an appropriate amount of 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran (DCM) orange dye into tris-(8-hydroxyquinoline) aluminum (Alq{sub 3}) emissive layer. Here, the blend of Alq{sub 3}:DCM is deposited in a single furnace crucible by various evaporation rates. The electro-optical behavior of organic light emitting diode devices is greatly influenced by varying the Alq{sub 3}:DCM film composition. It is investigated that when the deposition rate increased from 0.6 to 5 Å/s, complete energy transfer occurred from Alq{sub 3} to DCM and Electroluminescence (EL) peak shifted to higher wavelength regions. The device with evaporation rate of 0.6 Å/s shows a luminance of 3532 cd/m{sup 2} and maximum efficiency of 0.82 cd/A at 20 V. These blends show excellent orange emission host–guest system properties with easier deposition rate control. -- Highlight: • We fabricated light emitting layer by dissolving dyes in common solvent followed by thermal evaporation of dyes. • Achieving orange emissions with a single furnace. • We investigated for the first time Alq{sub 3}:DCM evaporation rate by using single furnace.

The process and risk of the CPR1000 cold function test in the cold area

International Nuclear Information System (INIS)

Liu Tinghao; Zhang Jian; Ji Dapeng; Shi Quanjian; Tian Kuo

2014-01-01

Hong yanhe nuclear power station is the first CPR1000 reactor which is under construction in the cold area of north China. It is also the first time to carry out the cold functional test (CFT) in the winter of north China. The preparation and process of CFT are described in the paper. According to the experience feedback of CFT of Unit 1, the risk and solution which are significance for the CFT of the other NPS in the cold area are analysed. (authors)

Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation.

Science.gov (United States)

Weiner, Juliane; Rohde, Kerstin; Krause, Kerstin; Zieger, Konstanze; Klöting, Nora; Kralisch, Susan; Kovacs, Peter; Stumvoll, Michael; Blüher, Matthias; Böttcher, Yvonne; Heiker, John T

2017-06-01

Several studies have demonstrated anti-diabetic and anti-obesogenic properties of visceral adipose tissue-derived serine protease inhibitor (vaspin) and so evoked its potential use for treatment of obesity-related diseases. The aim of the study was to unravel physiological regulators of vaspin expression and secretion with a particular focus on its role in brown adipose tissue (BAT) biology. We analyzed the effects of obesogenic diets and cold exposure on vaspin expression in liver and white and brown adipose tissue (AT) and plasma levels. Vaspin expression was analyzed in isolated white and brown adipocytes during adipogenesis and in response to adrenergic stimuli. DNA-methylation within the vaspin promoter was analyzed to investigate acute epigenetic changes after cold-exposure in BAT. Our results demonstrate a strong induction of vaspin mRNA and protein expression specifically in BAT of both cold-exposed and high-fat (HF) or high-sugar (HS) fed mice. While obesogenic diets also upregulated hepatic vaspin mRNA levels, cold exposure tended to increase vaspin gene expression of inguinal white adipose tissue (iWAT) depots. Concomitantly, vaspin plasma levels were decreased upon obesogenic or thermogenic triggers. Vaspin expression was increased during adipogenesis but unaffected by sympathetic activation in brown adipocytes. Analysis of vaspin promoter methylation in AT revealed lowest methylation levels in BAT, which were acutely reduced after cold exposure. Our data demonstrate a novel BAT-specific regulation of vaspin gene expression upon physiological stimuli in vivo with acute epigenetic changes that may contribute to cold-induced expression in BAT. We conclude that these findings indicate functional relevance and potentially beneficial effects of vaspin in BAT function.

Development of a model and test equipment for cold flow tests at 500 atm of small nuclear light bulb configurations

Science.gov (United States)

Jaminet, J. F.

1972-01-01

A model and test equipment were developed and cold-flow-tested at greater than 500 atm in preparation for future high-pressure rf plasma experiments and in-reactor tests with small nuclear light bulb configurations. With minor exceptions, the model chamber is similar in design and dimensions to a proposed in-reactor geometry for tests with fissioning uranium plasmas in the nuclear furnace. The model and the equipment were designed for use with the UARL 1.2-MW rf induction heater in tests with rf plasmas at pressures up to 500 atm. A series of cold-flow tests of the model was then conducted at pressures up to about 510 atm. At 504 atm, the flow rates of argon and cooling water were 3.35 liter/sec (STP) and 26 gal/min, respectively. It was demonstrated that the model is capable of being operated for extended periods at the 500-atm pressure level and is, therefore, ready for use in initial high-pressure rf plasma experiments.

The Crucible simulation: Behavioral simulation improves clinical leadership skills and understanding of complex health policy change.

Science.gov (United States)

Cohen, Daniel; Vlaev, Ivo; McMahon, Laurie; Harvey, Sarah; Mitchell, Andy; Borovoi, Leah; Darzi, Ara

2017-05-11

The Health and Social Care Act 2012 represents the most complex National Health Service reforms in history. High-quality clinical leadership is important for successful implementation of health service reform. However, little is known about the effectiveness of current leadership training. This study describes the use of a behavioral simulation to improve the knowledge and leadership of a cohort of medical doctors expected to take leadership roles in the National Health Service. A day-long behavioral simulation (The Crucible) was developed and run based on a fictitious but realistic health economy. Participants completed pre- and postsimulation questionnaires generating qualitative and quantitative data. Leadership skills, knowledge, and behavior change processes described by the "theory of planned behavior" were self-assessed pre- and postsimulation. Sixty-nine medical doctors attended. Participants deemed the simulation immersive and relevant. Significant improvements were shown in perceived knowledge, capability, attitudes, subjective norms, intentions, and leadership competency following the program. Nearly one third of participants reported that they had implemented knowledge and skills from the simulation into practice within 4 weeks. This study systematically demonstrates the effectiveness of behavioral simulation for clinical management training and understanding of health policy reform. Potential future uses and strategies for analysis are discussed. High-quality care requires understanding of health systems and strong leadership. Policymakers should consider the use of behavioral simulation to improve understanding of health service reform and development of leadership skills in clinicians, who readily adopt skills from simulation into everyday practice.

A one kPa centrifugal cold compressor for the 1.8 K helium refrigeration system of LHC

CERN Document Server

Saji, N; Yoshinaga, S; Itoh, K; Nogaku, T; Bézaguet, Alain-Arthur; Casas-Cubillos, J; Lebrun, P; Tavian, L

1998-01-01

CERN placed an order for a cold compressor prototype (CCP) with IHI for the LHC project. The CCP is supported by the oil-free magnetic bearings, driven by an induction motor. The compressor has the characteristics of high efficiency and wide operation range, thanks to the optimum design for the impeller and diffuser. The result of the performance tests at CERN showed that static heat in-leaks could be controlled at approx. 7.3 W, and an adiabatic efficiency is 75at a nominal flow of 18 g's with suction temperature of 4.4 K and suction pressure of 1 kPa. (4 refs).

Peripheral cold acclimatization in Antarctic scuba divers.

Science.gov (United States)

Bridgman, S A

1991-08-01

Peripheral acclimatization to cold in scuba divers stationed at the British Antarctic Survey's Signy Station was investigated during a year in Antarctica. Five divers and five non-diver controls underwent monthly laboratory tests of index finger immersion in cold water for 30 min. Index finger pulp temperature and time of onset of cold-induced vasodilatation (CIVD) were measured. Pain was recorded with verbal and numerical psychophysical subjective pain ratings. Average finger temperatures and median finger pain from 6-30 min of immersion, maximum finger temperatures during the first CIVD cycle, and finger temperatures at the onset of CIVD were calculated. Comparison of the variables recorded from divers and non-divers were performed with analysis of variance. No significant differences were found among the variables recorded from divers and non-divers. From a review of the literature, divers have responses typical of non-cold-adapted Caucasians. There is, therefore, no evidence that Signy divers peripherally acclimatized to cold. We suggest that these findings occur because either the whole body cooling which divers undergo inhibits peripheral acclimatization or because of insufficiently frequent or severe cold exposure while diving. Further basic studies on the duration, frequency and severity of cold exposure necessary to induce peripheral cold acclimatization are required before this question can be satisfactorily answered.

A taxonomy of inductive problems.

Science.gov (United States)

Kemp, Charles; Jern, Alan

2014-02-01

Inductive inferences about objects, features, categories, and relations have been studied for many years, but there are few attempts to chart the range of inductive problems that humans are able to solve. We present a taxonomy of inductive problems that helps to clarify the relationships between familiar inductive problems such as generalization, categorization, and identification, and that introduces new inductive problems for psychological investigation. Our taxonomy is founded on the idea that semantic knowledge is organized into systems of objects, features, categories, and relations, and we attempt to characterize all of the inductive problems that can arise when these systems are partially observed. Recent studies have begun to address some of the new problems in our taxonomy, and future work should aim to develop unified theories of inductive reasoning that explain how people solve all of the problems in the taxonomy.

Cold water recovery reduces anaerobic performance.

Science.gov (United States)

Crowe, M J; O'Connor, D; Rudd, D

2007-12-01

This study investigated the effects of cold water immersion on recovery from anaerobic cycling. Seventeen (13 male, 4 female) active subjects underwent a crossover, randomised design involving two testing sessions 2 - 6 d apart. Testing involved two 30-s maximal cycling efforts separated by a one-hour recovery period of 10-min cycling warm-down followed by either passive rest or 15-min cold water immersion (13 - 14 degrees C) with passive rest. Peak power, total work and postexercise blood lactate were significantly reduced following cold water immersion compared to the first exercise test and the control condition. These variables did not differ significantly between the control tests. Peak exercise heart rate was significantly lower after cold water immersion compared to the control. Time to peak power, rating of perceived exertion, and blood pH were not affected by cold water immersion compared to the control. Core temperature rose significantly (0.3 degrees C) during ice bath immersion but a similar increase also occurred in the control condition. Therefore, cold water immersion caused a significant decrease in sprint cycling performance with one-hour recovery between tests.

Actively controlling coolant-cooled cold plate configuration

Science.gov (United States)

Chainer, Timothy J.; Parida, Pritish R.

2015-07-28

A method is provided to facilitate active control of thermal and fluid dynamic performance of a coolant-cooled cold plate. The method includes: monitoring a variable associated with at least one of the coolant-cooled cold plate or one or more electronic components being cooled by the cold plate; and dynamically varying, based on the monitored variable, a physical configuration of the cold plate. By dynamically varying the physical configuration, the thermal and fluid dynamic performance of the cold plate are adjusted to, for example, optimally cool the one or more electronic components, and at the same time, reduce cooling power consumption used in cooling the electronic component(s). The physical configuration can be adjusted by providing one or more adjustable plates within the coolant-cooled cold plate, the positioning of which may be adjusted based on the monitored variable.

RNA-Seq-based analysis of cold shock response in Thermoanaerobacter tengcongensis, a bacterium harboring a single cold shock protein encoding gene.

Directory of Open Access Journals (Sweden)

Bo Liu

Full Text Available BACKGROUND: Although cold shock responses and the roles of cold shock proteins in microorganisms containing multiple cold shock protein genes have been well characterized, related studies on bacteria possessing a single cold shock protein gene have not been reported. Thermoanaerobacter tengcongensis MB4, a thermophile harboring only one known cold shock protein gene (TtescpC, can survive from 50° to 80 °C, but has poor natural competence under cold shock at 50 °C. We therefore examined cold shock responses and their effect on natural competence in this bacterium. RESULTS: The transcriptomes of T. tengcongensis before and after cold shock were analyzed by RNA-seq and over 1200 differentially expressed genes were successfully identified. These genes were involved in a wide range of biological processes, including modulation of DNA replication, recombination, and repair; energy metabolism; production of cold shock protein; synthesis of branched amino acids and branched-chain fatty acids; and sporulation. RNA-seq analysis also suggested that T. tengcongensis initiates cell wall and membrane remodeling processes, flagellar assembly, and sporulation in response to low temperature. Expression profiles of TtecspC and failed attempts to produce a TtecspC knockout strain confirmed the essential role of TteCspC in the cold shock response, and also suggested a role of this protein in survival at optimum growth temperature. Repression of genes encoding ComEA and ComEC and low energy metabolism levels in cold-shocked cells are the likely basis of poor natural competence at low temperature. CONCLUSION: Our study demonstrated changes in global gene expression under cold shock and identified several candidate genes related to cold shock in T. tengcongensis. At the same time, the relationship between cold shock response and poor natural competence at low temperature was preliminarily elucidated. These findings provide a foundation for future studies on genetic

How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation

Directory of Open Access Journals (Sweden)

McKemy David D

2005-04-01

Full Text Available Abstract Recognition of temperature is a critical element of sensory perception and allows us to evaluate both our external and internal environments. In vertebrates, the somatosensory system can discriminate discrete changes in ambient temperature, which activate nerve endings of primary afferent fibers. These thermosensitive nerves can be further segregated into those that detect either innocuous or noxious (painful temperatures; the latter neurons being nociceptors. We now know that thermosensitive afferents express ion channels of the transient receptor potential (TRP family that respond at distinct temperature thresholds, thus establishing the molecular basis for thermosensation. Much is known of those channels mediating the perception of noxious heat; however, those proposed to be involved in cool to noxious cold sensation, TRPM8 and TRPA1, have only recently been described. The former channel is a receptor for menthol, and links the sensations provided by this and other cooling compounds to temperature perception. While TRPM8 almost certainly performs a critical role in cold signaling, its part in nociception is still at issue. The latter channel, TRPA1, is activated by the pungent ingredients in mustard and cinnamon, but has also been postulated to mediate our perception of noxious cold temperatures. However, a number of conflicting reports have suggested that the role of this channel in cold sensation needs to be confirmed. Thus, the molecular logic for the perception of cold-evoked pain remains enigmatic. This review is intended to summarize our current understanding of these cold thermoreceptors, as well as address the current controversy regarding TRPA1 and cold signaling.

Social science in the Cold War.

Science.gov (United States)

Engerman, David C

2010-06-01

This essay examines ways in which American social science in the late twentieth century was--and was not--a creature of the Cold War. It identifies important work by historians that calls into question the assumption that all social science during the Cold War amounts to "Cold War social science." These historians attribute significant agency to social scientists, showing how they were enmeshed in both long-running disciplinary discussions and new institutional environments. Key trends in this scholarship include a broadening historical perspective to see social scientists in the Cold War as responding to the ideas of their scholarly predecessors; identifying the institutional legacies of World War II; and examining in close detail the products of extramural--especially governmental--funding. The result is a view of social science in the Cold War in which national security concerns are relevant, but with varied and often unexpected impacts on intellectual life.

Deciphering the Metabolic Changes Associated with Diapause Syndrome and Cold Acclimation in the Two-Spotted Spider Mite Tetranychus urticae

Science.gov (United States)

Khodayari, Samira; Moharramipour, Saeid; Larvor, Vanessa; Hidalgo, Kévin; Renault, David

2013-01-01

Diapause is a common feature in several arthropod species that are subject to unfavorable growing seasons. The range of environmental cues that trigger the onset and termination of diapause, in addition to associated hormonal, biochemical, and molecular changes, have been studied extensively in recent years; however, such information is only available for a few insect species. Diapause and cold hardening usually occur together in overwintering arthropods, and can be characterized by recording changes to the wealth of molecules present in the tissue, hemolymph, or whole body of organisms. Recent technological advances, such as high throughput screening and quantification of metabolites via chromatographic analyses, are able to identify such molecules. In the present work, we examined the survival ability of diapausing and non-diapausing females of the two-spotted spider mite, Tetranychus urticae, in the presence (0 or 5°C) or absence of cold acclimation. Furthermore, we examined the metabolic fingerprints of these specimens via gas chromatography-mass spectrophotometry (GC-MS). Partial Least Square Discriminant Analysis (PLS-DA) of metabolites revealed that major metabolic variations were related to diapause, indicating in a clear cut-off between diapausing and non-diapausing females, regardless of acclimation state. Signs of metabolic depression were evident in diapausing females, with most amino acids and TCA cycle intermediates being significantly reduced. Out of the 40 accurately quantified metabolites, seven metabolites remained elevated or were accumulated in diapausing mites, i.e. cadaverine, gluconolactone, glucose, inositol, maltose, mannitol and sorbitol. The capacity to accumulate winter polyols during cold-acclimation was restricted to diapausing females. We conclude that the induction of increased cold hardiness in this species is associated with the diapause syndrome, rather than being a direct effect of low temperature. Our results provide novel

A possible role for flowering locus T-encoding genes in interpreting environmental and internal cues affecting olive (Olea europaea L.) flower induction.

Science.gov (United States)

Haberman, Amnon; Bakhshian, Ortal; Cerezo-Medina, Sergio; Paltiel, Judith; Adler, Chen; Ben-Ari, Giora; Mercado, Jose Angel; Pliego-Alfaro, Fernando; Lavee, Shimon; Samach, Alon

2017-08-01

Olive (Olea europaea L.) inflorescences, formed in lateral buds, flower in spring. However, there is some debate regarding time of flower induction and inflorescence initiation. Olive juvenility and seasonality of flowering were altered by overexpressing genes encoding flowering locus T (FT). OeFT1 and OeFT2 caused early flowering under short days when expressed in Arabidopsis. Expression of OeFT1/2 in olive leaves and OeFT2 in buds increased in winter, while initiation of inflorescences occurred i n late winter. Trees exposed to an artificial warm winter expressed low levels of OeFT1/2 in leaves and did not flower. Olive flower induction thus seems to be mediated by an increase in FT levels in response to cold winters. Olive flowering is dependent on additional internal factors. It was severely reduced in trees that carried a heavy fruit load the previous season (harvested in November) and in trees without fruit to which cold temperatures were artificially applied in summer. Expression analysis suggested that these internal factors work either by reducing the increase in OeFT1/2 expression or through putative flowering repressors such as TFL1. With expected warmer winters, future consumption of olive oil, as part of a healthy Mediterranean diet, should benefit from better understanding these factors. © 2017 John Wiley & Sons Ltd.

Half Bridge Inductive Heater

Directory of Open Access Journals (Sweden)

Zoltán GERMÁN-SALLÓ

2015-12-01

Full Text Available Induction heating performs contactless, efficient and fast heating of conductive materials, therefore became one of the preferred heating procedure in industrial, domestic and medical applications. During induction heating the high-frequency alternating currents that heat the material are induced by means of electromagnetic induction. The material to be heated is placed inside the time-varying magnetic field generated by applying a highfrequency alternating current to an induction coil. The alternating electromagnetic field induces eddy currents in the workpiece, resulting resistive losses, which then heat the material. This paper describes the design of a power electronic converter circuit for induction heating equipment and presents the obtained results. The realized circuit is a low power half bridge resonant inverter which uses power MOS transistors and adequate driver circuits.

Cold-inducible RNA-binding protein mediates cold air inducible airway mucin production through TLR4/NF-κB signaling pathway.

Science.gov (United States)

Chen, Lingxiu; Ran, Danhua; Xie, Wenyue; Xu, Qing; Zhou, Xiangdong

2016-10-01

Mucus overproduction is an important feature in patients with chronic inflammatory airway diseases and cold air stimulation has been shown to be associated with the severity of these diseases. However, the regulatory mechanisms that mediate excessive mucin production under cold stress remain elusive. Recently, the cold-inducible RNA-binding protein (CIRP) has been shown to be markedly induced after exposure to cold air. In this study, we sought to explore the expression of CIRP within bronchial biopsy specimens, the effect on mucin5AC (MUC5AC) production in chronic inflammatory airway diseases and the potential signaling pathways involved in cold air stimulation process. We found that CIRP protein expression was significantly increased in patients with COPD and in mice treated with cold air. Moreover, cold air stimulation induced MUC5AC expression in wild-type mice but not in CIRP(-/-) mice. In vitro, cold air stress significantly elevated the transcriptional and protein expression levels of MUC5AC in human bronchial epithelial cells. CIRP, toll-like receptor 4 (TLR4) and phosphorylated NF-κB p65 (p-p65) increased significantly in response to cold stress and CIRP siRNA, TLR4 - neutralizing Ab and a specific inhibitor of NF-κB could attenuated cold stress inducible MUC5AC expression. In addition, CIRP siRNA could hindered the expression levels of TLR4 and p-p65 both induced by cold stress. Taken together, these results suggest that airway epithelial cells constitutively express CIRP in vitro and in vivo. CIRP is responsible for cold-inducible MUC5AC expression by activating TLR4/NF-κB signaling pathway. Copyright © 2016 Elsevier B.V. All rights reserved.

Accelerator-based pulsed cold neutron source

International Nuclear Information System (INIS)

Inoue, Kazuhiko; Iwasa, Hirokatsu; Kiyanagi, Yoshiaki

1979-01-01

An accelerator-based pulsed cold neutron source was constructed. The accelerator is a 35 MeV electron linear accelerator with 1 kW average beam power. The cold neutron beam intensity at a specimen is equivalent to that of a research reactor of 10 14 n/cm 2 .s thermal flux in the case of the quasi-elastic neutron scattering measurements. In spite of some limitations to the universal uses, it has been demonstrated by this facility that the modest capacity accelerator-based pulsed cold neutron source is a highly efficient cold neutron source with low capital investment. Design philosophy, construction details, performance and some operational experiences are described. (author)

Heat and cold accumulators in vehicles

Energy Technology Data Exchange (ETDEWEB)

Kauranen, P.; Wikstroem, L. (VTT Technical Research Centre of Finland, Advanced Materials, Tampere (Finland)); Heikkinen, J. (VTT Technical Research Centre of Finland, Building Services and Indoor Environment, Espoo (Finland)); Laurikko, J.; Elonen, T. (VTT Technical Research Centre of Finland, Emission Control, Espoo (Finland)); Seppaelae, A. (Helsinki Univ. of Technology, Applied Thermodynamics, Espoo (Finland)). Email: ari.seppala@tkk.fi

2009-07-01

Phase Change Material (PCM) based heat and cold accumulators have been tailored for transport applications including a mail delivery van as well as the cold chains of foodstuff and blood products. The PCMs can store relative large amount of thermal energy in a narrow temperature interval as latent heat of fusion of their melting and crystallization processes. Compact heat and cold accumulators can be designed using PCMs. The aim of the project has been to reduce the exhaust gas and noise emissions and improve the fuel economy of the transport systems and to improve the reliability of the cold chains studied by storing thermal energy in PCM accumulators. (orig.)

Cold suppresses agonist-induced activation of TRPV1.

Science.gov (United States)

Chung, M-K; Wang, S

2011-09-01

Cold therapy is frequently used to reduce pain and edema following acute injury or surgery such as tooth extraction. However, the neurobiological mechanisms of cold therapy are not completely understood. Transient receptor potential vanilloid 1 (TRPV1) is a capsaicin- and heat-gated nociceptive ion channel implicated in thermosensation and pathological pain under conditions of inflammation or injury. Although capsaicin-induced nociception, neuropeptide release, and ionic currents are suppressed by cold, it is not known if cold suppresses agonist-induced activation of recombinant TRPV1. We demonstrate that cold strongly suppressed the activation of recombinant TRPV1 by multiple agonists and capsaicin-evoked currents in trigeminal ganglia neurons under normal and phosphorylated conditions. Cold-induced suppression was partially impaired in a TRPV1 mutant that lacked heat-mediated activation and potentiation. These results suggest that cold-induced suppression of TRPV1 may share a common molecular basis with heat-induced potentiation, and that allosteric inhibition may contribute, in part, to the cold-induced suppression. We also show that combination of cold and a specific antagonist of TRPV1 can produce an additive suppression. Our results provide a mechanistic basis for cold therapy and may enhance anti-nociceptive approaches that target TRPV1 for managing pain under inflammation and tissue injury, including that from tooth extraction.

Inductive Reasoning and Writing

Science.gov (United States)

Rooks, Clay; Boyd, Robert

2003-01-01

Induction, properly understood, is not merely a game, nor is it a gimmick, nor is it an artificial way of explaining an element of reasoning. Proper understanding of inductive reasoning--and the various types of reasoning that the authors term inductive--enables the student to evaluate critically other people's writing and enhances the composition…

Facts about the Common Cold

Science.gov (United States)

... different viruses. Rhinovirus is the most common cause, accounting for 10 to 40 percent of colds. Other common cold viruses include coronavirus and ... RSS | Terms Of Use | Privacy | Sitemap Our Family Of Sites ... Introduction Risk Factors Screening Symptoms Tumor Testing Summary '; var ...

Phonon forces and cold denaturatio

DEFF Research Database (Denmark)

Bohr, Jakob

2003-01-01

Protein unfolds upon temperature reduction as Well as upon In increase in temperature, These phenomena are called cold denaturation and hot denaturation, respectively. The contribution from quantum mode forces to denaturation is estimated using a simple phenomenological model describing the molec......Protein unfolds upon temperature reduction as Well as upon In increase in temperature, These phenomena are called cold denaturation and hot denaturation, respectively. The contribution from quantum mode forces to denaturation is estimated using a simple phenomenological model describing...... the molecule Is a continuum. The frequencies of the vibrational modes depend on the molecular dimensionality; hence, the zero-point energies for the folded and the denatured protein are estimated to differ by several electron volts. For a biomolecule such an energy is significant and may contribute to cold...... denaturing. This is consistent with the empirical observation that cold denaturation is exothermic anti hot denaturation endothermic....

Cold gelation of globular proteins

NARCIS (Netherlands)

Alting, A.C.

2003-01-01

Keywords : globular proteins, whey protein, ovalbumin, cold gelation, disulfide bonds, texture, gel hardnessProtein gelation in food products is important to obtain desirable sensory and textural properties. Cold gelation is a novel method to produce protein-based gels. It is a two step process in

Monitoring the vaccine cold chain.

OpenAIRE

Cheriyan, E

1993-01-01

Maintaining the vaccine cold chain is an essential part of a successful immunisation programme. A continuous electronic temperature monitor helped to identify breaks in the cold chain in the community and the study led to the issue of proper guidelines and replacement of faulty equipment.

Frequent extreme cold exposure and brown fat and cold-induced thermogenesis: a study in a monozygotic twin.

Directory of Open Access Journals (Sweden)

Maarten J Vosselman

Full Text Available INTRODUCTION: Mild cold acclimation is known to increase brown adipose tissue (BAT activity and cold-induced thermogenesis (CIT in humans. We here tested the effect of a lifestyle with frequent exposure to extreme cold on BAT and CIT in a Dutch man known as 'the Iceman', who has multiple world records in withstanding extreme cold challenges. Furthermore, his monozygotic twin brother who has a 'normal' sedentary lifestyle without extreme cold exposures was measured. METHODS: The Iceman (subject A and his brother (subject B were studied during mild cold (13°C and thermoneutral conditions (31°C. Measurements included BAT activity and respiratory muscle activity by [18F]FDG-PET/CT imaging and energy expenditure through indirect calorimetry. In addition, body temperatures, cardiovascular parameters, skin perfusion, and thermal sensation and comfort were measured. Finally, we determined polymorphisms for uncoupling protein-1 and β3-adrenergic receptor. RESULTS: Subjects had comparable BAT activity (A: 1144 SUVtotal and B: 1325 SUVtotal, within the range previously observed in young adult men. They were genotyped with the polymorphism for uncoupling protein-1 (G/G. CIT was relatively high (A: 40.1% and B: 41.9%, but unlike during our previous cold exposure tests in young adult men, here both subjects practiced a g-Tummo like breathing technique, which involves vigorous respiratory muscle activity. This was confirmed by high [18F]FDG-uptake in respiratory muscle. CONCLUSION: No significant differences were found between the two subjects, indicating that a lifestyle with frequent exposures to extreme cold does not seem to affect BAT activity and CIT. In both subjects, BAT was not higher compared to earlier observations, whereas CIT was very high, suggesting that g-Tummo like breathing during cold exposure may cause additional heat production by vigorous isometric respiratory muscle contraction. The results must be interpreted with caution given the

Properties of cold components of symbiotic stars

International Nuclear Information System (INIS)

Luud, L.; Leehdyarv, L.

1986-01-01

Using the Blackwell-Shallis method the luminosities, temperatures and radii for cold components of symbiotic stars and for a sample of field red giants have been determined by means of infrared photometric observations. It turned out that the cold components of symbiotic stars do not differ from the normal red giants of the asymptotic branch. The masses of cold components of symbiotic stars have been found to be close to 3 M* (M* is the solar mass).The cold components of symbiotic stars do not fill their Roche lobes. About 10 times more carbon stars than the normal value in the vicinity of the Sun have been found among the cold components of symbiotic stars

Nonfreezing Cold-Induced Injuries

Science.gov (United States)

2012-01-01

cold injury. ( Modi - fi ed from Jia J, Pollock M: The pathogenesis of non-freezing cold nerve injury: Observations in the rat, Brain 120:631, 1997...myelitis and sinus development ( Figures 7-17 to 7-19 ). Appearance and behavior of the neuropathic foot have many similarities to those of the diabetic ...foot. In the diabetic foot, infections tend to be polymicrobial with Staphylococcus aureus, Staphylococcus epidermidis, and Enterococcus and

Arabidopsis COLD SHOCK DOMAIN PROTEIN2 is a RNA chaperone that is regulated by cold and developmental signals

International Nuclear Information System (INIS)

Sasaki, Kentaro; Kim, Myung-Hee; Imai, Ryozo

2007-01-01

Bacterial cold shock proteins (CSPs) are RNA chaperones that unwind RNA secondary structures. Arabidopsis COLD SHOCK DOMAIN PROTEIN2 (AtCSP2) contains a domain that is shared with bacterial CSPs. Here we showed that AtCSP2 binds to RNA and unwinds nucleic acid duplex. Heterologous expression of AtCSP2 complemented cold sensitivity of an Escherichia coli csp quadruple mutant, indicating that AtCSP2 function as a RNA chaperone in E. coli. AtCSP2 mRNA and protein levels increased during cold acclimation, but the protein accumulation was most prominent after 10 days of cold treatment. AtCSP2 promoter::GUS transgenic plants revealed that AtCSP2 is expressed only in root and shoot apical regions during vegetative growth but is expressed in reproductive organs such as pollens, ovules and embryos. These data indicated that AtCSP2 is involved in developmental processes as well as cold adaptation. Localization of AtCSP2::GFP in nucleolus and cytoplasm suggested different nuclear and cytosolic RNA targets

Cold fusion anomalies more perplexing than ever

International Nuclear Information System (INIS)

Dagani, R.

1989-01-01

This article addresses the debate over research on cold fusion. Analysis is made of the research efforts that have taken place since cold fusion was first thought to have been discovered in Utah. Research in the Soviet Union on the cold fusion phenomenon is also discussed

The study of genotype, cold pretreatment, low-dose gamma irradiation and 2,4-D concentration effect on wheat doubled haploid production

International Nuclear Information System (INIS)

Naserian, B.; Vedadi, C.; Karbalaii, S.

2005-01-01

Full text: In this study, response of a cultivar (Atrak) and two lines (F3 2005 and F3 2104) of wheat , and effect of cold pretreatment, low dose gamma irradiation and 2,4-D (2,4 mg l -1 ) were investigated to anther culture response. Donar plants were grown under field conditions in early spring. Anthers were plated on modified CHB medium containing 2, 4-D (2, 4 mg l -1 ), 0.5 mg l -1 Kinetin and 90 g l -1 Sucrose. Percent of Callus formation in 100 anther and percent of plantlet in 100 calli were measured. Results indicated that genotype, cold pretreatment and 2,4-D concentrations had significant effect on anther culture response. F3 2005 showed highest callus induction and plantlet production and F3 2104 had lowest response. This experiment indicated that androgenic traits are controlled by genotype and environmental factors. Further more these traits are controlled independently. (author)

Cold and heat waves in the United States.

Science.gov (United States)

Barnett, A G; Hajat, S; Gasparrini, A; Rocklöv, J

2012-01-01

Extreme cold and heat waves, characterized by a number of cold or hot days in succession, place a strain on people's cardiovascular and respiratory systems. The increase in deaths due to these waves may be greater than that predicted by extreme temperatures alone. We examined cold and heat waves in 99 US cities for 14 years (1987-2000) and investigated how the risk of death depended on the temperature threshold used to define a wave, and a wave's timing, duration and intensity. We defined cold and heat waves using temperatures above and below cold and heat thresholds for two or more days. We tried five cold thresholds using the first to fifth percentiles of temperature, and five heat thresholds using the 95-99 percentiles. The extra wave effects were estimated using a two-stage model to ensure that their effects were estimated after removing the general effects of temperature. The increases in deaths associated with cold waves were generally small and not statistically significant, and there was even evidence of a decreased risk during the coldest waves. Heat waves generally increased the risk of death, particularly for the hottest heat threshold. Cold waves of a colder intensity or longer duration were not more dangerous. Cold waves earlier in the cool season were more dangerous, as were heat waves earlier in the warm season. In general there was no increased risk of death during cold waves above the known increased risk associated with cold temperatures. Cold or heat waves earlier in the cool or warm season may be more dangerous because of a build up in the susceptible pool or a lack of preparedness for extreme temperatures. Copyright © 2011 Elsevier Inc. All rights reserved.

A pulse tube cryocooler with a cold reservoir

Science.gov (United States)

Zhang, X. B.; Zhang, K. H.; Qiu, L. M.; Gan, Z. H.; Shen, X.; Xiang, S. J.

2013-02-01

Phase difference between pressure wave and mass flow is decisive to the cooling capacity of regenerative cryocoolers. Unlike the direct phase shifting using a piston or displacer in conventional Stirling or GM cryocoolers, the pulse tube cyocooler (PTC) indirectly adjusts the cold phase due to the absence of moving parts at the cold end. The present paper proposed and validated theoretically and experimentally a novel configuration of PTC, termed cold reservoir PTC, in which a reservoir together with an adjustable orifice is connected to the cold end of the pulse tube. The impedance from the additional orifice to the cold end helps to increase the mass flow in phase with the pressure wave at the cold end. Theoretical analyses with the linear model for the orifice and double-inlet PTCs indicate that the cooling performance can be improved by introducing the cold reservoir. The preliminary experiments with a home-made single-stage GM PTC further validated the results on the premise of minor opening of the cold-end orifice.

Cold Sore

Science.gov (United States)

... may reduce how often they return. Symptoms A cold sore usually passes through several stages: Tingling and itching. Many people feel an itching, burning or tingling sensation around their lips for a day or so ...

Asymptomatic myocardial ischemia following cold provocation

International Nuclear Information System (INIS)

Shea, M.J.; Deanfield, J.E.; deLandsheere, C.M.; Wilson, R.A.; Kensett, M.; Selwyn, A.P.

1987-01-01

Cold is thought to provoke angina in patients with coronary disease either by an increase in myocardial demand or an increase in coronary vascular resistance. We investigated and compared the effects of cold pressor stimulation and symptom-limited supine bicycle exercise on regional myocardial perfusion in 35 patients with stable angina and coronary disease and in 10 normal subjects. Regional myocardial perfusion was assessed with positron emission tomography and rubidium-82. Following cold pressor stimulation 24 of 35 patients demonstrated significant abnormalities of regional myocardial perfusion with reduced cation uptake in affected regions of myocardium: 52 +/- 9 to 43 +/- 9 (p less than 0.001 vs normal subjects). Among these 24 patients only nine developed ST depression and only seven had angina. In contrast, 29 of 35 patients underwent supine exercise, and abnormal regional myocardial perfusion occurred in all 29, with a reduction in cation intake from 48 +/- 10 to 43 +/- 14 (p less than 0.001 vs normal subjects). Angina was present in 27 of 29 and ST depression in 25 of 29. Although the absolute decrease in cation uptake was somewhat greater following cold as opposed to exercise, the peak heart rate after cold was significantly lower than that after exercise (82 +/- 12 vs 108 +/- 16 bpm, p less than 0.05). Peak systolic blood pressures after cold and exercise were similar (159 +/- 24 vs 158 +/- 28). Thus, cold produces much more frequent asymptomatic disturbances of regional myocardial perfusion in patients with stable angina and coronary disease than is suggested by pain or ECG changes

Initial heating in cold cars

NARCIS (Netherlands)

Daanen, H.A.M.; Teunissen, L.P.J.; Hoogh, I.M. de

2012-01-01

During the initial minutes after entering a cold car, people feel uncomfortably cold. Six different warming systems were investigated in a small car in order to find out how to improve the feeling of comfort using 16 volunteers. The methods were: no additional warming next to a standard heating

Cold neutron radiography using low power accelerator

International Nuclear Information System (INIS)

Kiyanagi, Yoshiaki; Iwasa, Hirokatu

1993-01-01

A cold neutron source which can be adopted at a low power accelerator was studied. Time-of-flight radiography using the cold neutron source was performed. It is suggested that time-of-flight cold neutron radiography has possibility to distinguish the materials more clearly than the traditional film method since large contrast differences can be obtained by using digital data of the neutron intensity at different energies from thermal to cold region. Material will be identified at the same time by this method. (author)

Desensitization of menthol-activated cold receptors in lower extremities during local cooling in young women with a cold constitution.

Science.gov (United States)

Yamazaki, Fumio; Sone, Ryoko

2017-03-01

To test the hypothesis that topical menthol-induced reactivity of cold sensation and cutaneous vasoconstriction to local cooling is augmented in individuals with a cold constitution, we examined thermal sensation and cutaneous vasoconstrictor responses at menthol-treated and untreated sites in the legs during local skin cooling in young women complaining of chilliness (C group) and young women with no complaint as a normal control group (N group). During local skin cooling, the sensitivity to cold sensation was greater in the C group than in the N group. The application of menthol enhanced the cold sensation at a low temperature in the N group, but not in the C group. Cutaneous vasoconstrictor responses to local skin cooling were not altered by menthol treatment in either of the two groups. These findings suggest the desensitization of menthol-activated cold receptors in the legs of C group subjects, and a minor role of cold receptor activity in cutaneous vasoconstrictor response to local cooling.

Creep properties of 20% cold-worked Hastelloy XR

International Nuclear Information System (INIS)

Kurata, Y.

1996-01-01

The creep properties of Hastelloy XR, in solution-treated and in 20% cold-worked conditions, were studied at 800, 900 and 1000 C. At 800 C, the steady-state creep rate and rupture ductility decrease, while rupture life increases after cold work to 20%. Although the steady-state creep rate and ductility also decrease at 900 C, the beneficial effect on rupture life disappears. Cold work to 20% enhan ces creep resistance of this alloy at 800 and 900 C due to a high density of dislocations introduced by the cold work. Rupture life of the 20% cold-worked alloy becomes shorter and the steady-state creep rate larger at 1000 C during creep of the 20% cold-worked alloy. It is emphasized that these cold work effects should be taken into consideration in design and operation of high-temperature structural components of high-temperature gas-cooled reactors. (orig.)

RBE of thermal neutrons for induction of chromosome aberrations in human lymphocytes.

Science.gov (United States)

Schmid, E; Wagner, F M; Canella, L; Romm, H; Schmid, T E

2013-03-01

The induction of chromosome aberrations in human lymphocytes irradiated in vitro with slow neutrons was examined to assess the maximum low-dose RBE (RBE(M)) relative to (60)Co γ-rays. For the blood irradiations, cold neutron beam available at the prompt gamma activation analysis facility at the Munich research reactor FRM II was used. The given flux of cold neutrons can be converted into a thermally equivalent one. Since blood was taken from the same donor whose blood had been used for previous irradiation experiments using widely varying neutron energies, the greatest possible accuracy was available for such an estimation of the RBE(M) avoiding the inter-individual variations or differences in methodology usually associated with inter-laboratory comparisons. The magnitude of the coefficient α of the linear dose-response relationship (α = 0.400 ± 0.018 Gy(-1)) and the derived RBE(M) of 36.4 ± 13.3 obtained for the production of dicentrics by thermal neutrons confirm our earlier observations of a strong decrease in α and RBE(M) with decreasing neutron energy lower than 0.385 MeV (RBE(M) = 94.4 ± 38.9). The magnitude of the presently estimated RBE(M) of thermal neutrons is-with some restrictions-not significantly different to previously reported RBE(M) values of two laboratories.

Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist.

Science.gov (United States)

Hoffman, Hal M; Rosengren, Sanna; Boyle, David L; Cho, Jae Y; Nayar, Jyothi; Mueller, James L; Anderson, Justin P; Wanderer, Alan A; Firestein, Gary S

Familial cold autoinflammatory syndrome (FCAS) is an autosomal dominant disorder characterised by recurrent episodes of rash, arthralgia, and fever after cold exposure. The genetic basis of this disease has been elucidated. Cryopyrin, the protein that is altered in FCAS, is one of the adaptor proteins that activate caspase 1, resulting in release of interleukin 1. An experimental cold challenge protocol was developed to study the acute inflammatory mechanisms occurring after a general cold exposure in FCAS patients and to investigate the effects of pretreatment with an antagonist of interleukin 1 receptor (IL-1Ra). ELISA, real-time PCR, and immunohistochemistry were used to measure cytokine responses. After cold challenge, untreated patients with FCAS developed rash, fever, and arthralgias within 1-4 h. Significant increases in serum concentrations of interleukin 6 and white-blood-cell counts were seen 4-8 h after cold challenge. Serum concentrations of interleukin 1 and cytokine mRNA in peripheral-blood leucocytes were not raised, but amounts of interleukin 1 protein and mRNA were high in affected skin. IL-1Ra administered before cold challenge blocked symptoms and increases in white-blood-cell counts and serum interleukin 6. The ability of IL-1Ra to prevent the clinical features and haematological and biochemical changes in patients with FCAS indicates a central role for interleukin 1beta in this disorder. Involvement of cryopyrin in activation of caspase 1 and NF-kappaB signalling suggests that it might have a role in many chronic inflammatory diseases. These findings support a new therapy for a disorder with no previously known acceptable treatment. They also offer insights into the role of interleukin 1beta in more common inflammatory diseases.

21 CFR 880.6085 - Hot/cold water bottle.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hot/cold water bottle. 880.6085 Section 880.6085... Devices § 880.6085 Hot/cold water bottle. (a) Identification. A hot/cold water bottle is a device intended for medical purposes that is in the form of a container intended to be filled with hot or cold water...

Practicing induction:

DEFF Research Database (Denmark)

Sprogøe, Jonas; Rohde, Nicolas

2009-01-01

We claim that induction potentially triggers both individual and organizational learning and by drawing on practice-based theory we discuss how the interplay between individual and organization, what we call a generative dance, ignites both kinds of learning.......We claim that induction potentially triggers both individual and organizational learning and by drawing on practice-based theory we discuss how the interplay between individual and organization, what we call a generative dance, ignites both kinds of learning....

Thinking about the cold fusion fever

International Nuclear Information System (INIS)

Kitsunezaki, Akio

1989-01-01

The excitement since March 23 on cold fusion seems to be unprecedented evidence that the people of the world are waiting for fusion power with much enthusiasm. Cold fusion is really a surprise because it does not need high temperature and because it seems to be easy to enlarge the test tube into a useful power source if the claim by Professors Pons and Fleischmann at the University of Utah are true. The second announcement of cold fusion came from the Brigham Young University, also in the state of Utah, by Professor Jones, but his report was totally different from that given by Pons and Fleischmann. From the beginning of the 'fever', physicists have been very skeptical about cold fusion. Most of the critics and criticisms are targeted on Pons and Fleischmann rather than Jones, because not only was their paper poor but also their statements have not been scientific. They insisted that the heat came from fusion reaction, but without any scientific proof. They had not carried out the basic control experiment by running the same test with ordinary water instead of heavy water. A meeting on cold fusion was held at JAERI on May 15. At the end of the meeting, the some 260 attendants knew that cold fusion was not conceivable with the current scientific knowledge. (N.K.)

Cold neutron source with self-regulation

International Nuclear Information System (INIS)

Kawai, T.

2003-01-01

A way to increase the cold neutron flux is to cool moderator from where cold neutrons are extracted. Although various kinds of cooling system are considered, the closed thermo-siphon cooling system is adopted in many institutes. The notable feature of this system is to be able to keep the liquid level stable in the moderator cell against thermal disturbances, by using self-regulation, which allows a stable supply of cold neutrons. The main part of the closed thermo-siphon consists of a condenser, a moderator transfer tube and moderator cell, which is called the hydrogen cold system. When an extra heat load is applied to the hydrogen cold system having no flow resistance in a moderator transfer tube, the system pressure rises by evaporation of liquid hydrogen. Then the boiling point of hydrogen rises. The liquefaction capacity of the condenser is increasing with a rise of temperature, because a refrigerating power of the helium refrigerator increases linearly with temperature rise of the system. Therefore, the effect of thermal heat load increase is compensated and cancelled out. The closed thermo-siphon has this feature generally, when the moderator transfer tube is designed to be no flow resistance. The report reviews the concept of self-regulation, and how to design and construct the cold neutron source with self-regulation. (author)

PLUGM: a coupled thermal-hydraulic computer model for freezing melt flow in a channel

International Nuclear Information System (INIS)

Pilch, M.

1982-01-01

PLUGM is a coupled thermal-hydraulic computer model for freezing liquid flow and plugging in a cold channel. PLUGM is being developed at Sandia National Laboratories for applications in Sandia's ex-vessel Core Retention Concept Assessment Program and in Sandia's LMFBR Transition Phase Program. The purpose of this paper is to introduce PLUGM and demonstrate how it can be used in the analysis of two of the core retention concepts under investigation at Sandia: refractory brick crucibles and particle beds

Radioactive wastes: the challenge of volumes reduction

International Nuclear Information System (INIS)

Lepetit, V.

2005-01-01

The reduction of radioactive waste volumes is a priority for the French atomic energy commission (CEA) and for the Areva group. This article gives a rapid overview of the equipments and processes used to separate the valorizable materials from the ultimate wastes: pulsed separation columns and evaporators for the liquid-liquid extraction, compactification of spent fuel hulls, remote handling systems, recoverable colloid for surface decontamination, decontaminating foam, hydrothermal oxidation of organic and aqueous effluents, cold crucible vitrification etc. (J.S.)

Cold fusion

International Nuclear Information System (INIS)

Suh, Suk Yong; Sung, Ki Woong; Kang, Joo Sang; Lee, Jong Jik

1995-02-01

So called 'cold fusion phenomena' are not confirmed yet. Excess heat generation is very delicate one. Neutron generation is most reliable results, however, the records are erratic and the same results could not be repeated. So there is no reason to exclude the malfunction of testing instruments. The same arguments arise in recording 4 He, 3 He, 3 H, which are not rich in quantity basically. An experiment where plenty of 4 He were recorded is attached in appendix. The problem is that we are trying to search cold fusion which is permitted by nature or not. The famous tunneling effect in quantum mechanics will answer it, however, the most fusion rate is known to be negligible. The focus of this project is on the theme that how to increase that negligible fusion rate. 6 figs, 4 tabs, 1512 refs. (Author)

Hot shot induction and reperfusion with a specific blocker of the es-ENT1 nucleoside transporter before and after hypothermic cardioplegia abolishes myocardial stunning in acutely ischemic hearts despite metabolic derangement: Hot shot drug delivery before hypothermic cardioplegia

Science.gov (United States)

Abd-Elfattah, Anwar Saad; Tuchy, Gert E.; Jessen, Michael E.; Salter, David R.; Goldstein, Jacques P.; Brunsting, Louis A.; Wechsler, Andrew S.

2013-01-01

Objective Simultaneous inhibition of the cardiac equilibrative-p-nitrobenzylthioinosine (NBMPR)–sensitive (es) type of the equilibrative nucleoside transport 1 (ENT1) nucleoside transporter, with NBMPR, and adenosine deaminase, with erythro-9-[2-hydroxy-3-nonyl]adenine (EHNA), prevents release of myocardial purines and attenuates myocardial stunning and fibrillation in canine models of warm ischemia and reperfusion. It is not known whether prolonged administration of hypothermic cardioplegia influences purine release and EHNA/NBMPR-mediated cardioprotection in acutely ischemic hearts. Methods Anesthetized dogs (n = 46), which underwent normothermic aortic crossclamping for 20 minutes on-pump, were divided to determine (1) purine release with induction of intermittent antegrade or continuous retrograde hypothermic cardioplegia and reperfusion, (2) the effects of postischemic treatment with 100 µM EHNA and 25 µM NBMPR on purine release and global functional recovery, and (3) whether a hot shot and reperfusion with EHNA/NBMPR inhibits purine release and attenuates ventricular dysfunction of ischemic hearts. Myocardial biopsies and coronary sinus effluents were obtained and analyzed using high-performance liquid chromatography. Results Warm ischemia depleted myocardial adenosine triphosphate and elevated purines (ie, inosine > adenosine) as markers of ischemia. Induction of intermittent antegrade or continuous retrograde hypothermic (4°C) cardioplegia releases purines until the heart becomes cold (90% of purines in coronary sinus effluent. Reperfusion with EHNA/NBMPR abolished ventricular dysfunction in acutely ischemic hearts with and without a hot shot and hypothermic cardioplegic arrest. Conclusions Induction of hypothermic cardioplegia releases purines from ischemic hearts until they become cold, whereas reperfusion induces massive purine release and myocardial stunning. Inhibition of cardiac es-ENT1 nucleoside transporter abolishes postischemic reperfusion

Understanding Colds: Anatomy of the Nose

Science.gov (United States)

... Complications Special Features References Common Cold Understanding Colds Anatomy of the Nose The nose contains shelf-like ... white). Soft tissue, such as the eye, is gray. The maxillary sinus of adults has a volume ...

High Time Resolution Measurements of VOCs from Vehicle Cold Starts: The Air Toxic Cold Start Pulse

Science.gov (United States)

Jobson, B. T.; Huangfu, Y.; Vanderschelden, G. S.

2017-12-01

Pollutants emitted during motor vehicle cold starts, especially in winter in some climates, is a significant source of winter time air pollution. While data exist for CO, NO, and total hydrocarbon emissions from federal testing procedures for vehicle emission certification, little is known about the emission rates of individual volatile organic compounds, in particular the air toxics benzene, formaldehyde, and acetaldehyde. Little is known about the VOC speciation and temperature dependence for cold starts. The US EPA vehicle emission model MOVES assumes that cold start emissions have the same speciation profile as running emissions. We examined this assumption by measuring cold start exhaust composition for 4 vehicles fueled with E10 gasoline over a temperature range of -4°C to 10°C in winter of 2015. The extra cold start emissions were determined by comparison with emissions during engine idling. In addition to CO and NOx measurements a proton transfer reaction mass spectrometer was used to measure formaldehyde, acetaldehyde, benzene, toluene, and C2-alkylbenzenes at high time resolution to compare with the cold start emission speciation profiles used in the EPA MOVES2014 model. The results show that after the vehicle was started, CO mixing ratios can reach a few percent of the exhaust and then drop to several ppmv within 2 minutes of idling, while NOx showed different temporal behaviors among the four vehicles. VOCs displayed elevated levels during cold start and the peak mixing ratios can be two orders higher than idling phase levels. Molar emission ratios relative to toluene were used to compare with the emission ratio used in MOVES2014 and we found the formaldehyde-to-toluene emission ratio was about 0.19, which is 5 times higher than the emission ratio used in MOVES2014 and the acetaldehyde-to-toluene emission ratios were 0.86-0.89, which is 8 times higher than the ones in MOVES2014. The C2-alkylbenzene-to-toluene ratio agreed well with moves. Our results

Regulatory networks in pollen development under cold stress

Directory of Open Access Journals (Sweden)

Kamal Dev Sharma

2016-03-01

Full Text Available Cold stress modifies anthers’ metabolic pathways to induce pollen sterility. Cold-tolerant plants, unlike the susceptible ones, produce high proportion of viable pollen. Anthers in susceptible plants, when exposed to cold stress, increase abscisic acid (ABA metabolism and reduce ABA catabolism. Increased ABA negatively regulates expression of tapetum cell wall bound invertase and monosaccharide transport genes resulting in distorted carbohydrate pool in anther. Cold-stress also reduces endogenous levels of the bioactive gibberellins (GAs, GA4 and GA7, in susceptible anthers by repression of the GA biosynthesis genes. Here we discuss recent findings on mechanisms of cold susceptibility in anthers which determine pollen sterility. We also discuss differences in regulatory pathways between cold-stressed anthers of susceptible and tolerant plants that decide pollen sterility or viability.

Economic implications of labor induction.

Science.gov (United States)

Garcia-Simon, Raquel; Montañes, Antonio; Clemente, Jesús; Del Pino, María D; Romero, Manuel A; Fabre, Ernesto; Oros, Daniel

2016-04-01

To assess health service costs associated with labor induction according to different clinical situations in a tertiary-level hospital. In a prospective study, individual patient cost data were assessed for women admitted for induction of labor at a tertiary hospital in Spain between November 1, 2012, and August 31, 2013. The costs of labor induction were estimated according to maternal and neonatal outcomes, method of delivery, cervical condition at admission, and obstetric indication. Direct costs including professional fees, epidural, maternal stay, consumables, and drugs were calculated. Overall, 412 women were included in the final cost analysis. The mean total cost of labor induction was €3589.87 (95% confidence interval [CI] 3475.13-3704.61). Cesarean delivery after labor induction (€4830.45, 95% CI 4623.13-5037.58) was significantly more expensive than spontaneous delivery (€3037.45, 95% CI 2966.91-3179.99) and instrumental vaginal delivery (€3344.31, 95%CI 3151.69-3536.93). The total cost for patients with a very unfavorable cervix (Bishop score Labor induction for hypertensive disorders of pregnancy was the most expensive obstetric indication for induction of labor (€4347.32, 95% CI 3890.45-4804.18). Following the induction of labor, a number of patient- and treatment-related factors influence costs associated with delivery. Copyright © 2015 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

Inductive line energy storage generator

Energy Technology Data Exchange (ETDEWEB)

Choi, P [Ecole Polytechnique, Palaiseau (France). Laboratoire de Physique des Milieux Ionises

1997-12-31

The inductive energy storage (IES) generator has long been considered to be the most efficient system for energy usage in large pulsed power system at the MA level. A number of parameters govern the efficiency of energy transfer between the storage capacitors and the load, and the level of current deliverable to the load. For high power system, the energy storage capacitors are arranged as a Marx generator. The primary constraints are the inductances in the various parts of the circuit, in particular, the upstream inductance between the Marx and the POS, and the downstream inductance between the POS and the load. This paper deals with the effect of replacing part of the upstream inductance with a transmission line and introduces the new concept of an inductive line for energy storage (ILES). Extensive parametric scans were carried out on circuit simulations to investigate the effect of this upstream transmission line. A model was developed to explain the operation of the ILES design based on the data obtained. Comparison with an existing IES generator shows that the ILES design offers a significant improvement in the maximum current and hence energy delivered to an inductive load. (author). 5 figs., 1 ref.

Vector control of induction machines

CERN Document Server

Robyns, Benoit

2012-01-01

After a brief introduction to the main law of physics and fundamental concepts inherent in electromechanical conversion, ""Vector Control of Induction Machines"" introduces the standard mathematical models for induction machines - whichever rotor technology is used - as well as several squirrel-cage induction machine vector-control strategies. The use of causal ordering graphs allows systematization of the design stage, as well as standardization of the structure of control devices. ""Vector Control of Induction Machines"" suggests a unique approach aimed at reducing parameter sensitivity for

Preparation of translationally cold neutral molecules.

Science.gov (United States)

Di Domenicantonio, Giulia; Bertsche, Benjamin; Osterwalder, Andreas

2011-01-01

Efforts at EPFL to obtain translationally cold neutral molecules are described. Active deceleration of polar molecules is performed by confining the molecules in moving three-dimensional electrostatic traps, and by appropriately choosing the velocity of those traps. Alternatively, cold molecules can be obtained by velocity filtering. Here, the velocity of the molecules is not changed, but instead the cold molecules are extracted from a thermal sample by using the competition between the electrostatic force and the centrifugal force inside a bent electrostatic guide for polar molecules.

The status of cold fusion

Science.gov (United States)

Storms, E.

This report attempts to update the status of the phenomenon of cold fusion. The new field is continuing to grow as a variety of nuclear reactions are discovered to occur in a variety of chemical environments at modest temperatures. However, it must be cautioned that most scientists consider cold fusion as something akin to UFO's, ESP, and numerology.

Inductive Reasoning: A Training Approach

Science.gov (United States)

Klauer, Karl Josef; Phye, Gary D.

2008-01-01

Researchers have examined inductive reasoning to identify different cognitive processes when participants deal with inductive problems. This article presents a prescriptive theory of inductive reasoning that identifies cognitive processing using a procedural strategy for making comparisons. It is hypothesized that training in the use of the…

Inductive Monitoring System (IMS)

Data.gov (United States)

National Aeronautics and Space Administration — IMS: Inductive Monitoring System The Inductive Monitoring System (IMS) is a tool that uses a data mining technique called clustering to extract models of normal...

Hesitant birth of cold fusion

International Nuclear Information System (INIS)

Bockris, J.O.

1992-01-01

John O'M. Bockris, a distinguished chemistry professor at Texas A ampersand M University, finds the reaction to the announcement of the discovery of cold fusion curious. Two years earlier, he notes, there had been a comparable announcement concerning the discovery of high-temperature superconductivity; it received favorable press coverage for months. The cold-fusion announcement, on the other hand, was met with dour skepticism. When other researchers failed in efforts to duplicate the findings of Martin Fleischmann and B. Stanley Pons, Bockris says, the two scientists were held up to ridicule. Bockris says he found a deep emotional opposition to cold fusion, even within his own department and university. This opposition is fueled in large part, he believes, by big science and the hot fusion lobby. A key indicator of cold fusion is the presence of tritium, Brockis claims. At Texas A ampersand M, large amounts of tritium have been found in some experiments; this also has occurred in experiments at more than 40 laboratories in nine countries, he says. Excess heat production is more difficult to attain, he acknowledges. The cold-fusion controversy has uncovered some unflattering characteristics of the scientific community, Bockris says. Among them are: scientists are no less driven by emotion that business people or politicians; research funding decisions serve to perpetuate the goals of politically powerful interest groups; and ideas have great inertia once planted in a scientist's mind

Public Perception of Extreme Cold Weather-Related Health Risk in a Cold Area of Northeast China.

Science.gov (United States)

Ban, Jie; Lan, Li; Yang, Chao; Wang, Jian; Chen, Chen; Huang, Ganlin; Li, Tiantian

2017-08-01

A need exists for public health strategies regarding extreme weather disasters, which in recent years have become more frequent. This study aimed to understand the public's perception of extreme cold and its related health risks, which may provide detailed information for public health preparedness during an extreme cold weather event. To evaluate public perceptions of cold-related health risk and to identify vulnerable groups, we collected responses from 891 participants in a face-to-face survey in Harbin, China. Public perception was measured by calculating the score for each perception question. Locals perceived that extreme cold weather and related health risks were serious, but thought they could not avoid these risks. The significant difference in perceived acceptance level between age groups suggested that the elderly are a "high health risk, low risk perception" group, meaning that they are relatively more vulnerable owing to their high susceptibility and low awareness of the health risks associated with extreme cold weather. The elderly should be a priority in risk communication and health protective interventions. This study demonstrated that introducing risk perception into the public health field can identify vulnerable groups with greater needs, which may improve the decision-making of public health intervention strategies. (Disaster Med Public Health Preparedness. 2017;11:417-421).

Formation of cold molecules through the photo-association of cold atoms of Cesium. Existence of long range forces between between cold excited atoms of Cesium

International Nuclear Information System (INIS)

Comparat, D.

1999-09-01

This thesis deals with the experimental study and the theoretical interpretation of the processes involved in photo-association and the formation of cold caesium molecules. It also presents a study of the dipolar forces between a pair of cold excited caesium atoms. We present here the first photo-association experiment on cold caesium atoms: two cold atoms absorb a photon to form an excited electronically excited molecules in a rotation-vibration level. The first production of cold molecules which was realised experimentally, after the spontaneous deexcitation of the photo-associated molecules, is described, stressing the role of the potential well of the molecular states O g - (6s+6p 3/2 ) or 1 u (6s+6p 3/2 ) of caesium. The detection of the formed caesium molecules is based on a two-photons resonant ionisation that creates Cs 2 + ions, afterwards selectively detected. Temperatures around 20-200 μK have been measured. The photo-associative spectroscopy is described on the theoretical point of view: a detailed theoretical study allows to calculate precisely the asymptotic parts of the potential curves. On the experimental point of view, we present the spectroscopy of the extern potential well of the caesium state O g - (6s+6p 3/2 ) and the construction of an effective potential curve of the RKR type. A unified theory of photo-association in weak field, considered as a collision assisted by laser, is developed. The cold atoms experiments allow to study and control the collision between two atoms whose mutual interaction is of the dipole-dipole type. Two different physical systems are studied: a sample of Rydberg atoms, and the photo-association process which is a laser-assisted collision. A modification of the motion of one pair of atoms makes it possible to control the bipolar forces and to choose the atoms relative speeds. (author)

Two cold-season derechoes in Europe

Science.gov (United States)

Gatzen, Christoph; Púčik, Tomas; Ryva, David

2011-06-01

In this study, we apply for the first time the definition of a derecho (Johns and Hirt, 1987) to European cold-season convective storm systems. These occurred on 18 January 2007 and 1 March 2008, respectively, and they are shown to fulfill the criteria of a derecho. Damaging winds were reported over a distance of 1500 km and locally reached F3 intensity. Synoptic analysis for the events reveal strongly forced situations that have been described for cold-season derechoes in the United States. A comparison of swaths of damaging winds, radar structures, detected lightning, cold pool development, and cloud-top temperatures indicates that both derechoes formed along cold fronts that were affected by strong quasi-geostrophic forcing. It seems that the overlap of the cold front position with the strong differential cyclonic vorticity advection at the cyclonic flank of mid-level jet streaks favoured intense convection and high winds. The movement and path width of the two derechoes seemed to be related to this overlap. The wind gust intensity that was also different for both events is discussed and could be related to the component of the mid-level winds perpendicular to the gust fronts.

Influence of cold deformation and annealing on hydrogen embrittlement of cold hardening bainitic steel for high strength bolts

Energy Technology Data Exchange (ETDEWEB)

Hui, Weijun, E-mail: wjhui@bjtu.edu.cn [School of Mechanical, Electronic and Control Engineering, Beijing Jiaotong University, Beijing 100044 (China); Zhang, Yongjian; Zhao, Xiaoli; Shao, Chengwei [School of Mechanical, Electronic and Control Engineering, Beijing Jiaotong University, Beijing 100044 (China); Wang, Kaizhong; Sun, Wei; Yu, Tongren [Technical Center, Maanshan Iron & Steel Co., Ltd., Maanshan 243002, Anhui (China)

2016-04-26

The influence of cold drawing and annealing on hydrogen embrittlement (HE) of newly developed cold hardening bainitic steel was investigated by using slow strain rate testing (SSRT) and thermal desorption spectrometry (TDS), for ensuring safety performance of 10.9 class high strength bolts made of this kind of steel against HE under service environments. Hydrogen was introduced into the specimen by electrochemical charging. TDS analysis shows that the hydrogen-charged cold drawn specimen exhibits an additional low-temperature hydrogen desorption peak besides the original high-temperature desorption peak of the as-rolled specimen, causing remarkable increase of absorbed hydrogen content. It is found that cold drawing significantly enhances the susceptibility to HE, which is mainly attributed to remarkable increase of diffusible hydrogen absorption, the occurrence of strain-induced martensite as well as the increase of strength level. Annealing after cold deformation is an effective way to improve HE resistance and this improvement strongly depends on annealing temperature, i.e. HE susceptibility decreases slightly with increasing annealing temperature up to 200 °C and then decreases significantly with further increasing annealing temperature. This phenomenon is explained by the release of hydrogen, the recovery of cold worked microstructure and the decrease of strength with increasing annealing temperature.

International cooperation in cold forging technology

DEFF Research Database (Denmark)

Bay, Niels; Lange, K

1992-01-01

International cooperation in the field of cold forging technology started in 1961 by formation of the OECD Group of Experts on Metal Forming. In 1967 this group was transformed into the International Cold Forging Group, ICFG, an independent body which has now been operative for 25 years. Members...... of the ICFG are personally elected by the Plenary as experts within the field, often representing national groups within cold forging. The main work within the ICFG is carried out in its subgroups which are established by the Plenary to collect, compile and evaluate data and eventually also produce data...... by cooperative activities or by instigating national research. These subgroups have produced 9 data sheets and 7 guidelines on subjects such as materials, tool design and construction, calculation methods for cold forging tools, manufacture of slugs, lubrication aspects and small quantity production. Plenary...

Purification by high vacuum fusion and progressive solidification of uranium from electrolytic origin

International Nuclear Information System (INIS)

Poeydomenge, P.

1964-01-01

Within the general framework of research on uranium purification by zone melting, an attempt was made to determine the degree of purification which could be obtained by a simple gradual solidification of a normal nuclear-pure uranium paying close attention to the rate and direction of solidification. This uranium of intermediate purity would provide a starting material more suited to the first purification which is a vertical zone-melting process, so-called 'floating'. For this purpose, ingots of electrolytic uranium were melted under vacuum (2 to 5 x 10 -6 mm) in a long crucible after a slow rise in temperature to eliminate as much as possible the gases and volatiles impurities. This degassing and impurities volatilisation are completed by maintaining both at a high temperature for a considerable time. The beth is then made to solidify from the one an in the other the crucible by slowly moving the solid-liquid interface at a constant rate so as to obtain an impurity distribution according to the laws established by PFANN. Various experimental methods have made it possible to show that the metal which solidifies first is much purer than that at the other end of the ingot. The degree of purification of the metal at the beginning of the ingot has been evaluated either quantitatively by measuring the ratio of the electrical resistivities at room temperature and at the liquid nitrogen temperature, or qualitatively by an examination of the micrographic structure and by a study of the recrystallisation of the metal. On the one hand the purified metal re-crystallises during iso-chromic annealings carried out at increasing temperatures, at a temperature much lower than the initial metal or than the end of the ingot. The passage from the cold-worked state to the recrystallised state is followed by micro-hardness measurements. On the other end, only is the purified metal, strongly cold-worked by unidirectional melting, is the phenomenon of 'dissociative growth' of the grain

Cold fusion

Energy Technology Data Exchange (ETDEWEB)

Suh, Suk Yong; Sung, Ki Woong; Kang, Joo Sang; Lee, Jong Jik [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1995-02-01

So called `cold fusion phenomena` are not confirmed yet. Excess heat generation is very delicate one. Neutron generation is most reliable results, however, the records are erratic and the same results could not be repeated. So there is no reason to exclude the malfunction of testing instruments. The same arguments arise in recording {sup 4}He, {sup 3}He, {sup 3}H, which are not rich in quantity basically. An experiment where plenty of {sup 4}He were recorded is attached in appendix. The problem is that we are trying to search cold fusion which is permitted by nature or not. The famous tunneling effect in quantum mechanics will answer it, however, the most fusion rate is known to be negligible. The focus of this project is on the theme that how to increase that negligible fusion rate. 6 figs, 4 tabs, 1512 refs. (Author).

Cold chain management: Knowledge and practices in primary ...

African Journals Online (AJOL)

Administrator

experience and their knowledge of cold chain was not as per required levels to support effective cold chain management. ... district directorates who then supply them to the various ..... Finn L, Crook S. A district survey of vaccine cold chain ...

Contrôle épigénétique de l'induction et de la tolérance à la montaison chez la betterave sucrière

OpenAIRE

Hebrard , Claire

2012-01-01

Sugar beet is a biennial plant with an absolute requirement of vernalization, corresponding to the acquisition of the competence to bolt and flower after a prolonged exposure to low temperatures. The cold duration needed to induce bolting and flowering varies depending on the genotypes, reflecting their bolting tolerance, which is an essential agronomic trait. This work aimed at (i) investigating a possible epigenetic control of bolting induction in bolting sensitive and bolting resistant sug...

Prediction of cold flow properties of Biodiesel

Directory of Open Access Journals (Sweden)

Parag Saxena

2016-08-01

Full Text Available Biodiesel being environmentally friendly is fast gaining acceptance in the market as an alternate diesel fuel. But compared to petroleum diesel it has certain limitations and thus it requires further development on economic viability and improvement in its properties to use it as a commercial fuel. The cold flow properties play a major role in the usage of biodiesel commercially as it freezes at cold climatic conditions. In the present study, cold flow properties of various types of biodiesel were estimated by using correlations available in literature. The correlations were evaluated based on the deviation between the predicted value and experimental values of cold flow properties.

The Cold Chain Logistics for Perishable Agricultural Products in China

OpenAIRE

Hou Yanfang; Xie Dong; Wang Jianbo

2015-01-01

This study introduces concepts of the agricultural product cold chain logistics and domestic and international researches. Also, the study discusses issues of Chinese agricultural cold chain logistics in the development process as the following aspects: the dividing of cold chain logistics market, refrigeration hardware facilities, third-party cold chain logistics development, the level of cold chain technologies, cold chain logistics professionals and the legal system and the standard system...

Perception of foot temperature in young women with cold constitution: analysis of skin temperature and warm and cold sensation thresholds.

Science.gov (United States)

Sadakata, Mieko; Yamada, Yoshiaki

2007-06-01

To examine the disease state of cold constitution, physiological measurements of the foot were conducted by investigating thermal sensations under an environmental condition of 25 degrees C-26 degrees C (neutral temperature) in 29 young women with and without cold constitution. The subjects were classified into 3 groups according to their experiences with cold constitution: cold constitution, intermediate, and normal groups. Foot skin temperature was measured by thermography. Thermal sensations were measured on the dorsum of the left foot using a thermal stimulator. Cold and warm spots on the dorsum of the right foot were ascertained. Thermal stimulation was delivered by a copper probe. No significant differences in foot skin temperature among these 3 groups were identified as measured in a laboratory under neutral temperature conditions. However, the mean warm sensation threshold was +6.3+/-1.09 degrees C (mean+/-SEM) for the cold constitution group (n=14), +3.4+/-2.10 degrees C (mean+/-SEM) for the intermediate group (n=7), and -0.25+/-1.96 degrees C (mean+/-SEM) for the normal group (n=6). The difference was significant between the cold constitution and normal groups. No significant differences among the 3 groups were found in the cold sensation threshold. This may be attributable to the distribution of thermal receptors and to chronically reduced blood flow in subcutaneous tissues, where the skin temperature receptors responsible for temperature sensation are located.

An empirical model for friction in cold forging

DEFF Research Database (Denmark)

Bay, Niels; Eriksen, Morten; Tan, Xincai

2002-01-01

With a system of simulative tribology tests for cold forging the friction stress for aluminum, steel and stainless steel provided with typical lubricants for cold forging has been determined for varying normal pressure, surface expansion, sliding length and tool/work piece interface temperature...... of normal pressure and tool/work piece interface temperature. The model is verified by process testing measuring friction at varying reductions in cold forward rod extrusion. KEY WORDS: empirical friction model, cold forging, simulative friction tests....

Effect of Inductive Coil Shape on Sensing Performance of Linear Displacement Sensor Using Thin Inductive Coil and Pattern Guide

Directory of Open Access Journals (Sweden)

Hiroyuki Wakiwaka

2011-11-01

Full Text Available This paper discusses the effect of inductive coil shape on the sensing performance of a linear displacement sensor. The linear displacement sensor consists of a thin type inductive coil with a thin pattern guide, thus being suitable for tiny space applications. The position can be detected by measuring the inductance of the inductive coil. At each position due to the change in inductive coil area facing the pattern guide the value of inductance is different. Therefore, the objective of this research is to study various inductive coil pattern shapes and to propose the pattern that can achieve good sensing performance. Various shapes of meander, triangular type meander, square and circle shape with different turn number of inductive coils are examined in this study. The inductance is measured with the sensor sensitivity and linearity as a performance evaluation parameter of the sensor. In conclusion, each inductive coil shape has its own advantages and disadvantages. For instance, the circle shape inductive coil produces high sensitivity with a low linearity response. Meanwhile, the square shape inductive coil has a medium sensitivity with higher linearity.

Acute Cold / Restraint Stress in Castrated Rats

Directory of Open Access Journals (Sweden)

Farideh Zafari Zangeneh

2008-09-01

Full Text Available Objective: The present study aimed to determine whether castration altered osmotically stimulated vasopressin (VP release and urinary volume and what is the role of endocrine-stress axis in this process.Materials and methods: Totally 108 mice were studied in two main groups of castrated (n=78 and control (n=30. Each group was extracted by acute cold stress (4◦C for 2h/day, restraint stress (by syringes 60cc 2h/day and cold/restraint stress. The castrated group was treated in sub groups of testosterone, control (sesame oil as vehicle of testosterone. Propranolol as blocker of sympathetic nervous system was given to both groups of castrated mice and main control.Results: Our results showed that, there is interactions between testosterone and sympathetic nervous system on vasopressin, because urine volume was decreased only in testoctomized mice with cold/restraint and cold stress (P<0.001; propranolol as the antagonist of sympathetic nervous system could block and increase urine volume in castrated mice. This increased volume of urine was due to acute cold stress, not restraint stress (p<0.001. The role of testosterone, noradrenalin (NA and Vasopressin (VP in the acute cold stress is confirmed, because testosterone could return the effect of decreased urine volume in control group (P<0.001. Conclusion: Considering the effect of cold/restraint stress on urinary volume in castrated mice shows that there is interaction between sex hormone (testosterone, vasopressin and adrenergic systems.

Reactor cold neutron source facility, the first in Japan

International Nuclear Information System (INIS)

Utsuro, Masahiko; Maeda, Yutaka; Kawai, Takeshi; Tashiro, Tameyoshi; Sakakibara, Shoji; Katada, Minoru.

1986-01-01

In the Research Reactor Institute, Kyoto University, the first cold neutron source facility for the reactor in Japan was installed, and various tests are carried out outside the reactor. Nippon Sanso K.K. had manufactured it. After the prescribed tests outside the reactor, this facility will be installed soon in the reactor, and its outline is described on this occasion. Cold neutrons are those having very small energy by being cooled to about-250 deg C. Since the wavelength of the material waves of cold neutrons is long, and their energy is small, they are very advantageous as an experimental means for clarifying the structure of living body molecules and polymers, the atom configuration in alloys, and atomic and molecular movements by neutron scattering and neutron diffraction. The basic principle of the cold neutron source facility is to irradiate thermal neutrons on a cold moderator kept around 20 K, and to moderate and cool the neutrons by nuclear scattering to convert to cold neutrons. The preparatory research on cold neutrons and hydrogen liquefaction, the basic design to put the cold neutron source facility in the graphite moderator facility, the safety countermeasures, the manufacture and quality control, the operation outside the reactor and the performance are reported. The cold neutron source facility comprises a cold moderator tank and other main parts, a deuterium gas tank, a helium refrigerator and instrumentation. (Kako, I.)

Development of nondestructive measurement of cold work rate, (2)

International Nuclear Information System (INIS)

Kamimura, Hideaki; Igarashi, Miyuki; Satoh, Masakazu; Miura, Makoto

1978-01-01

Cold-worked type 316 stainless steel will be used as fuel cladding material for the proto-type fast reactor MONJU. Cold work rate is an important parameter in swelling behavior of fuel cladding. It has been shown that austenitic stainless steel undergoes martensitic transformation during cold working. Nondestructive evaluation of cold work rate will be expected by measuring residual magnetism produced in the presence of martensitic phase when cold worked austenitic stainless steel is magnetized. In the previous work, the residual magnetism of cladding tubes of type 316 stainless steel was measured. The results have shown high degree of the correlation between residual magnetism and cold work rate. This paper reports the results of measurement on cold-rolled type 316 stainless steel plate samples. Dimensions of the specimens are 100 mm long and 3.5 and 7 mm wide. The apparatus and experimental procedures were similar to the previous work. Good agreement was found between the estimated cold work rate obtained in the previous work and that for cold rolled plate specimens. Measurement of residual magnetism in identical direction with magnetization showed smaller dispersion of data as compared with that in transverse direction. The residual magnetism near specimen surface hardly decreased when the surface of specimen was chemically removed. The reason for the comparative decrease in residual magnetism at 10% and 15% cold work rate is not clear. (Wakatsuki, Y.)

The use of cold plasma generators in medicine

Directory of Open Access Journals (Sweden)

Kolomiiets R.O.

2017-04-01

Full Text Available Cold plasma treatment of wounds is a modern area of therapeutic medicine. We describe the physical mechanisms of cold plasma, the principles of therapeutic effects and design of two common types of cold plasma generators for medical use. This work aims at disclosing the basic principles of construction of cold atmospheric plasma generators in medicine and prospects for their further improvement. The purpose of this work is to improve the existing cold atmospheric plasma generators for use in medical applications. Novelty of this work consists in the application of new principles of construction of cold atmospheric plasmas medical apparatus, namely the combination of the gas discharge chamber, electrodes complex shape forming device and plasma flow in a single package. This helps to achieve a significant reduction in the size of the device, and a discharge chamber design change increases the therapeutic effect. The design of cold atmospheric plasma generator type «pin-to-hole», which is able to control parameters using the plasma current (modulation fluctuations in the primary winding and mechanically (using optional rotary electrode. It is also possible to combine some similar generators in the set, which will increase the surface area of the plasma treatment. We consider the basic principles of generating low atmospheric plasma flow, especially the formation of the plasma jet, changing its shape and modulation stream. The features of cold plasma generator design and information about prospects for further application, and opportunities for further improvement are revealed. The recommendations for further use of cold atmospheric plasma generators in medicine are formulated.

High-temperature mechanical properties of high-purity 70 mass% Cr-Fe alloy

Energy Technology Data Exchange (ETDEWEB)

Asahina, M.; Harima, N.; Takaki, S.; Abiko, K. [Tohoku Univ., Sendai (Japan). Inst. for Materials Research

2002-01-16

An ingot of high-purity 70 mass% Cr-Fe alloy was prepared by high-frequency induction melting in a high-purity argon atmosphere using a cold copper crucible. Its tensile properties such as hot-ductility and tensile strength were measured, and compared with the results for a high-purity 50 mass% Cr-Fe alloy, a high-purity 60 mass% Cr-Fe alloy and a Ni-based super-alloy. The formation of {sigma}-phase was also examined. The purity of a 70Cr-Fe alloy (70 mass% Cr-Fe alloy) ingot is more than 99.98 mass% and the total amount of gaseous impurities (C, N, O, S, H) in the 70Cr-Fe alloy is 69.9 mass ppm. The strength of the 70Cr-Fe alloy is higher than those of the 60Cr-Fe alloy and the 50Cr-Fe alloy at the temperatures between 293 and 1573 K, without decrease in ductility with increasing Cr content. The 70Cr-Fe alloy also possesses excellent high-temperature ductility. The {sigma}-phase was not observed after aging of 3.6 Ms at 873 K. Consequently, the 70Cr-Fe alloy is an excellent alloy as the base of super heat-resistant alloys. (orig.)

Intraspecies differences in cold hardiness, carbohydrate content and β-amylase gene expression of Vaccinium corymbosum during cold acclimation and deacclimation.

Science.gov (United States)

Lee, Jun Hyung; Yu, Duk Jun; Kim, Su Jin; Choi, Doil; Lee, Hee Jae

2012-12-01

Changes in cold hardiness, carbohydrate content and β-amylase gene expression were monitored in the shoots of the highbush blueberry (Vaccinium corymbosum L.) cultivars 'Sharpblue' and 'Jersey' during cold acclimation (CA) and deacclimation (DA). The seasonal patterns were similar in both cultivars, but the levels of cold hardiness determined by electrolyte leakage analysis were significantly different; 'Jersey' was hardier than 'Sharpblue'. Cold hardiness was closely related to total soluble sugar content (r = -0.98** and -0.99** for 'Sharpblue' and 'Jersey', respectively). In 'Jersey', more soluble sugars accumulated during CA. Of the detected soluble sugars, glucose, fructose and raffinose contents were significantly associated with cold hardiness in both cultivars. Sucrose was abundant in both cultivars, and stachyose content changed significantly during CA and DA. However, they were not associated with cold hardiness. A sharp decrease in starch contents in the middle of CA coincided with β-amylase gene (VcBMY) expression, indicating the conversion of starch into soluble sugars. During CA, VcBMY was expressed up to twofold higher in 'Jersey' than in 'Sharpblue'. These results suggest that intraspecies differences in the cold hardiness of highbush blueberries are associated with total soluble sugar content, which is driven partly by differential expression of VcBMY.

The Combined Effect of Cold and Moisture on Manual Performance.

Science.gov (United States)

Ray, Matthew; Sanli, Elizabeth; Brown, Robert; Ennis, Kerri Ann; Carnahan, Heather

2018-02-01

Objective The aim of this study was to investigate the combined effect of cold and moisture on manual performance and tactile sensitivity. Background People working in the ocean environment often perform manual work in cold and wet conditions. Although the independent effects of cold and moisture on hand function are known, their combined effect has not been investigated. Method Participants completed sensory (Touch-Test, two-point discrimination) and motor (Purdue Pegboard, Grooved Pegboard, reef knot untying) tests in the following conditions: dry hand, wet hand, cold hand, and cold and wet hand. Results For the Purdue Pegboard and knot untying tasks, the greatest decrement in performance was observed in the cold-and-wet-hand condition, whereas the decrements seen in the cold-hand and wet-hand conditions were similar. In the Grooved Pegboard task, the performance decrements exhibited in the cold-and-wet-hand condition and the cold-hand condition were similar, whereas no decrement was observed in the wet-hand condition. Tactile sensitivity was reduced in the cold conditions for the Touch-Test but not the two-point discrimination test. The combined effect of cold and moisture led to the largest performance decrements except when intrinsic object properties helped with grasp maintenance. The independent effects of cold and moisture on manual performance were comparable. Application Tools and equipment for use in the cold ocean environment should be designed to minimize the effects of cold and moisture on manual performance by including object properties that enhance grasp maintenance and minimize the fine-dexterity requirements.

Heat shock protection against cold stress of Drosophila melanogaster

OpenAIRE

Burton, Vicky; Mitchell, Herschel K.; Young, Patricia; Petersen, Nancy S.

1988-01-01

Heat shock protein synthesis can be induced during recovery from cold treatment of Drosophila melanogaster larvae. Survival of larvae after a cold treatment is dramatically improved by a mild heat shock just before the cold shock. The conditions which induce tolerance to cold are similar to those which confer tolerance to heat.

Expert Cold Structure Development

Science.gov (United States)

Atkins, T.; Demuysere, P.

2011-05-01

The EXPERT Program is funded by ESA. The objective of the EXPERT mission is to perform a sub-orbital flight during which measurements of critical aero- thermodynamic phenomena will be obtained by using state-of-the-art instrumentation. As part of the EXPERT Flight Segment, the responsibility of the Cold Structure Development Design, Manufacturing and Validation was committed to the Belgian industrial team SONACA/SABCA. The EXPERT Cold Structure includes the Launcher Adapter, the Bottom Panel, the Upper Panel, two Cross Panels and the Parachute Bay. An additional Launcher Adapter was manufactured for the separation tests. The selected assembly definition and manufacturing technologies ( machined parts and sandwich panels) were dictated classically by the mass and stiffness, but also by the CoG location and the sensitive separation interface. Used as support for the various on-board equipment, the Cold Structure is fixed to but thermally uncoupled from the PM 1000 thermal shield. It is protect on its bottom panel by a thermal blanket. As it is a protoflight, analysis was the main tool for the verification. Low level stiffness and modal analysis tests have also been performed on the Cold Structure equipped with its ballast. It allowed to complete its qualification and to prepare SONACA/SABCA support for the system dynamic tests foreseen in 2011. The structure was finally coated with a thermal control black painting and delivered on time to Thales Alenia Space-Italy end of March 201.

Cold versus hot fusion deuterium branching ratios

International Nuclear Information System (INIS)

Fox, H.; Bass, R.

1995-01-01

A major source of misunderstanding of the nature of cold nuclear fusion has been the expectation that the deuterium branching ratios occurring within a palladium lattice would be consistent with the gas-plasma branching ratios. This misunderstanding has led to the concept of the dead graduate student, the 1989's feverish but fruitless search for neutron emissions from cold fusion reactors, and the follow-on condemnation of the new science of cold fusion. The experimental facts are that in a properly loaded palladium lattice, the deuterium fusion produces neutrons at little above background, a greatly less-than-expected production of tritium (the tritium desert), and substantially more helium-4 than is observed in hot plasma physics. The experimental evidence is now compelling (800 reports of success from 30 countries) that cold nuclear fusion is a reality, that the branching ratios are unexpected, and that a new science is struggling to be recognized. Commercialization of some types of cold fusion devices has already begun

Improving cold chain systems: Challenges and solutions.

Science.gov (United States)

Ashok, Ashvin; Brison, Michael; LeTallec, Yann

2017-04-19

While a number of new vaccines have been rolled out across the developing world (with more vaccines in the pipeline), cold chain systems are struggling to efficiently support national immunization programs in ensuring the availability of safe and potent vaccines. This article reflects on the Clinton Health Access Initiative, Inc. (CHAI) experience working since 2010 with national immunization programs and partners to improve vaccines cold chains in 10 countries-Ethiopia, Nigeria, Kenya, Malawi, Tanzania, Uganda, Cameroon, Mozambique, Lesotho and India - to identify the root causes and solutions for three common issues limiting cold chain performance. Key recommendations include: Collectively, the solutions detailed in this article chart a path to substantially improving the performance of the cold chain. Combined with an enabling global and in-country environment, it is possible to eliminate cold chain issues as a substantial barrier to effective and full immunization coverage over the next few years. Copyright © 2017. Published by Elsevier Ltd.

Combining Maize Base Germplasm for Cold Tolerance Breeding

OpenAIRE

Rodríguez Graña, Víctor Manuel; Butrón Gómez, Ana María; Sandoya Miranda, Germán; Ordás Pérez, Amando; Revilla Temiño, Pedro

2007-01-01

Early planting can contribute to increased grain yield of maize (Zea mays L.), but it requires cold tolerance. A limited number of cold-tolerant maize genotypes have been reported. The objectives of this study were to test a new strategy to improve cold tolerance in maize searching for broad x narrow genetic combinations that may be useful as base populations for breeding programs, to compare genotype performance under cold-controlled and field conditions, and to establish the major genetic e...

Cold stress induces lower urinary tract symptoms.

Science.gov (United States)

Imamura, Tetsuya; Ishizuka, Osamu; Nishizawa, Osamu

2013-07-01

Cold stress as a result of whole-body cooling at low environmental temperatures exacerbates lower urinary tract symptoms, such as urinary urgency, nocturia and residual urine. We established a model system using healthy conscious rats to explore the mechanisms of cold stress-induced detrusor overactivity. In this review, we summarize the basic findings shown by this model. Rats that were quickly transferred from room temperature (27 ± 2°C) to low temperature (4 ± 2°C) showed detrusor overactivity including increased basal pressure and decreased voiding interval, micturition volume, and bladder capacity. The cold stress-induced detrusor overactivity is mediated through a resiniferatoxin-sensitve C-fiber sensory nerve pathway involving α1-adrenergic receptors. Transient receptor potential melastatin 8 channels, which are sensitive to thermal changes below 25-28°C, also play an important role in mediating the cold stress responses. Additionally, the sympathetic nervous system is associated with transient hypertension and decreases of skin surface temperature that are closely correlated with the detrusor overactivity. With this cold stress model, we showed that α1-adrenergic receptor antagonists have the potential to treat cold stress-exacerbated lower urinary tract symptoms. In addition, we showed that traditional Japanese herbal mixtures composed of Hachimijiogan act, in part, by increasing skin temperature and reducing the number of cold sensitive transient receptor potential melastatin channels in the skin. The effects of herbal mixtures have the potential to treat and/or prevent the exacerbation of lower urinary tract symptoms by providing resistance to the cold stress responses. Our model provides new opportunities for utilizing animal disease models with altered lower urinary tract functions to explore the effects of novel therapeutic drugs. © 2013 The Japanese Urological Association.

A novel combination technique of cold crystalloid perfusion but not cold storage facilitates transplantation of canine hearts donated after circulatory death.

Science.gov (United States)

Rosenfeldt, Franklin; Ou, Ruchong; Salamonsen, Robert; Marasco, Silvana; Zimmet, Adam; Byrne, Joshua; Cosic, Filip; Saxena, Pankaj; Esmore, Donald

2016-11-01

Donation after circulatory death (DCD) represents a potential new source of hearts to increase the donor pool. We showed previously that DCD hearts in Greyhound dogs could be resuscitated and preserved by continuous cold crystalloid perfusion but not by cold static storage and could demonstrate excellent contractile and metabolic function on an in vitro system. In the current study, we demonstrate that resuscitated DCD hearts are transplantable. Donor Greyhound dogs (n = 12) were divided into perfusion (n = 8) and cold static storage (n = 4) groups. General anesthesia was induced and ventilation ceased for 30 minutes to achieve circulatory death. Donor cardiectomy was performed, and for 4 hours the heart was preserved by controlled reperfusion, followed by continuous cold perfusion with an oxygenated crystalloid perfusate or by static cold storage, after which orthotopic heart transplantation was performed. Recovery was assessed over 4 hours by hemodynamic monitoring. During cold perfusion, hearts showed continuous oxygen consumption and low lactate levels, indicating aerobic metabolism. The 8 dogs in the perfusion group were weaned off bypass, and 4 hours after bypass produced cardiac output of 4.73 ± 0.51 liters/min, left ventricular power of 7.63 ± 1.32 J/s, right ventricular power of 1.40 ± 0.43 J/s, and left ventricular fractional area shortening of 39.1% ± 5.2%, all comparable to pre-transplant values. In the cold storage group, 3 of 4 animals could not be weaned from cardiopulmonary bypass, and the fourth exhibited low-level function. Cold crystalloid perfusion, but not cold static storage, can resuscitate and preserve the DCD donor heart in a canine model of heart transplantation, thus rendering it transplantable. Controlled reperfusion and cold crystalloid perfusion have potential for clinical application in DCD transplantation. Copyright © 2016. Published by Elsevier Inc.

From mains frequency to converter power supply in foundry melting operations; Von der Netzfrequenz- zur Umrichter-Stromversorgung im Schmelzbetrieb der Eisengiesserei

Energy Technology Data Exchange (ETDEWEB)

Doetsch, Erwin; Yildir, Yilmaz [ABP Induction Systems GmbH, Dortmund (Germany); Koch, Frank [Gusstec Weiherhammer GmbH, Weiherhammer (Germany)

2010-06-15

As is well known, converter-based power feed has now largely superseded line-frequency technology as state-of-the-art in supply of induction melting facilities. Replacement of LF power supply systems with converters is therefore the main priority in the context of projects for modernization of existing induction installations. The objective is generally to leave the crucible furnace and its peripherals effectively as they are, and match the output and frequency of the converter to their needs. The following article states the criteria that need to be taken into account in this context and examines a specific modernization project, using the example of Gusstec Weiherhammer GmbH's iron melting installation. (orig.)

A novel behavioral assay for measuring cold sensation in mice.

Science.gov (United States)

Brenner, Daniel S; Golden, Judith P; Gereau, Robert W

2012-01-01

Behavioral models of cold responses are important tools for exploring the molecular mechanisms of cold sensation. To complement the currently cold behavioral assays and allow further studies of these mechanisms, we have developed a new technique to measure the cold response threshold, the cold plantar assay. In this assay, animals are acclimated on a glass plate and a cold stimulus is applied to the hindpaw through the glass using a pellet of compressed dry ice. The latency to withdrawal from the cooled glass is used as a measure of the cold response threshold of the rodents, and the dry ice pellet provides a ramping cold stimulus on the glass that allows the correlation of withdrawal latency values to rough estimates of the cold response threshold temperature. The assay is highly sensitive to manipulations including morphine-induced analgesia, Complete Freund's Adjuvant-induced inflammatory allodynia, and Spinal Nerve Ligation-induced neuropathic allodynia.

Cryogenic refrigeration for cold neutron sources

International Nuclear Information System (INIS)

Gistau-Baguer, Guy

1998-01-01

Neutron moderation by means of a fluid at cryogenic temperature is a very interesting way to obtain cold neutrons. Today, a number of nuclear research reactors are using this technology. This paper deals with thermodynamics and technology which are used for cooling Cold Neutron Sources

Cold valleys in fusion and fission

International Nuclear Information System (INIS)

Misicu, S.

2003-01-01

The cold fission configuration after the preformation of the fragments resembles a short-lived dinuclear or quasi-molecular system. The most conceivable scission configuration is given by two fission fragments in touching with the symmetry axes aligned (pole-pole orientation). This conclusion was based on the simple argument that this configuration offers the optimal tunneling time, i.e. the difference between the Coulomb barrier and the decay energy Q is minimal. Other orientations are apparently precluded in cold spontaneous fission and should be regarded as quasi-fission doorways in the synthesis of superheavy elements by cold fusion. (orig.)

Human Physiological Responses to Acute and Chronic Cold Exposure

Science.gov (United States)

Stocks, Jodie M.; Taylor, Nigel A. S.; Tipton, Michael J.; Greenleaf, John E.

2001-01-01

When inadequately protected humans are exposed to acute cold, excessive body heat is lost to the environment and unless heat production is increased and heat loss attenuated, body temperature will decrease. The primary physiological responses to counter the reduction in body temperature include marked cutaneous vasoconstriction and increased metabolism. These responses, and the hazards associated with such exposure, are mediated by a number of factors which contribute to heat production and loss. These include the severity and duration of the cold stimulus; exercise intensity; the magnitude of the metabolic response; and individual characteristics such as body composition, age, and gender. Chronic exposure to a cold environment, both natural and artificial, results in physiological alterations leading to adaptation. Three quite different, but not necessarily exclusive, patterns of human cold adaptation have been reported: metabolic, hypothermic, and insulative. Cold adaptation has also been associated with an habituation response, in which there is a desensitization, or damping, of the normal response to a cold stress. This review provides a comprehensive analysis of the human physiological and pathological responses to cold exposure. Particular attention is directed to the factors contributing to heat production and heat loss during acute cold stress, and the ability of humans to adapt to cold environments.

Studies and modeling of cold neutron sources

International Nuclear Information System (INIS)

Campioni, G.

2004-11-01

With the purpose of updating knowledge in the fields of cold neutron sources, the work of this thesis has been run according to the 3 following axes. First, the gathering of specific information forming the materials of this work. This set of knowledge covers the following fields: cold neutron, cross-sections for the different cold moderators, flux slowing down, different measurements of the cold flux and finally, issues in the thermal analysis of the problem. Secondly, the study and development of suitable computation tools. After an analysis of the problem, several tools have been planed, implemented and tested in the 3-dimensional radiation transport code Tripoli-4. In particular, a module of uncoupling, integrated in the official version of Tripoli-4, can perform Monte-Carlo parametric studies with a spare factor of Cpu time fetching 50 times. A module of coupling, simulating neutron guides, has also been developed and implemented in the Monte-Carlo code McStas. Thirdly, achieving a complete study for the validation of the installed calculation chain. These studies focus on 3 cold sources currently functioning: SP1 from Orphee reactor and 2 other sources (SFH and SFV) from the HFR at the Laue Langevin Institute. These studies give examples of problems and methods for the design of future cold sources

Evaluation of slurry preparation procedures for the determination of mercury by axial view inductively coupled plasma optical emission spectrometry using on-line cold vapor generation

International Nuclear Information System (INIS)

Santos, Eder Jose dos; Herrmann, Amanda Beatriz; Antunes Vieira, Mariana; Azzolin Frescura, Vera Lucia; Curtius, Adilson Jose

2005-01-01

Five different slurry preparation procedures were tested, after grinding the solid samples to a particle size ≤53 μm: (1) using aqua regia plus HF, 30 min of sonication, standing time of 24 h followed by another 30 min of sonication; (2) same as the previous one, except that the standing time and the second ultrasound treatment were omitted; (3) same as the previous one, except that HF was not used; (4) same as the previous one, except that the aqua regia was replaced by nitric acid; (5) same as the previous one, except that the acid nitric was replaced by tetramethylammonium hydroxide (TMAH). The Hg vapor was generated on-line, and the emission signal intensity measured at 253.652 nm by axial view inductively coupled plasma optical emission spectrometry. Initially, four experimental conditions were optimized using a multivariate factorial analysis: the concentrations of HCl and of the reducing agent, NaBH 4 , used in the cold vapor generation, and two instrumental parameters, the plasma radiofrequency power and the carrier gas flow rate. The radiofrequency power was statistically significant, but limited to 1.2 kW for practical reasons. The procedures were applied to 11 biological and environmental materials. Both, the slurries and the filtrates were analyzed, using calibration solutions in the same medium as in the slurries. The first three procedures produced results in agreement with the certified values. The two last procedures, using nitric acid or TMHA could not be used for quantitative analysis. For practical reasons, Procedure 3, with a detection limit (3s, n=10) of 0.06 μg g -1 for a sample mass of 20 mg in a final volume of 15 mL is recommended. The relative standard deviations for mercury in the investigated materials, using the recommended procedure, were lower than 12.5%, indicating a good precision for slurry sampling. The recommended procedure is simple, rapid and robust

Cold forming of aluminium - State of the art

DEFF Research Database (Denmark)

Bay, Niels

1997-01-01

The ongoing development of cold forging technology has been manifested lately by the increasing application of components in cold forged aluminium alloys. Applying precipitation hardening alloys components with great strength/weight ratio can be produced with a strength comparable...... to that of unalloyed steel. After description of the different types of alloys and their individual properties and applications, the special requirements for tool design by cold forging in aluminium is discussed. Finally, a large number of industrial examples on cold forged aluminium components are presented. (C) 1997...

De Novo Transcriptome Sequencing and the Hypothetical Cold Response Mode of Saussurea involucrata in Extreme Cold Environments.

Science.gov (United States)

Li, Jin; Liu, Hailiang; Xia, Wenwen; Mu, Jianqiang; Feng, Yujie; Liu, Ruina; Yan, Panyao; Wang, Aiying; Lin, Zhongping; Guo, Yong; Zhu, Jianbo; Chen, Xianfeng

2017-06-07

Saussurea involucrata grows in high mountain areas covered by snow throughout the year. The temperature of this habitat can change drastically in one day. To gain a better understanding of the cold response signaling pathways and molecular metabolic reactions involved in cold stress tolerance, genome-wide transcriptional analyses were performed using RNA-Seq technologies. A total of 199,758 transcripts were assembled, producing 138,540 unigenes with 46.8 Gb clean data. Overall, 184,416 (92.32%) transcripts were successfully annotated. The 365 transcription factors identified (292 unigenes) belonged to 49 transcription factor families associated with cold stress responses. A total of 343 transcripts on the signal transduction (132 upregulated and 212 downregulated in at least any one of the conditions) were strongly affected by cold temperature, such as the CBL-interacting serine/threonine-protein kinase ( CIPKs ), receptor-like protein kinases , and protein kinases . The circadian rhythm pathway was activated by cold adaptation, which was necessary to endure the severe temperature changes within a day. There were 346 differentially expressed genes (DEGs) related to transport, of which 138 were upregulated and 22 were downregulated in at least any one of the conditions. Under cold stress conditions, transcriptional regulation, molecular transport, and signal transduction were involved in the adaptation to low temperature in S. involucrata . These findings contribute to our understanding of the adaptation of plants to harsh environments and the survival traits of S. involucrata . In addition, the present study provides insight into the molecular mechanisms of chilling and freezing tolerance.

Observation of stars produced during cold fusion

International Nuclear Information System (INIS)

Matsumoto, T.

1992-01-01

It has been indicated tht multiple-neutron nuclei such as quad-neutrons can be emitted during cold fusion. These multiple-neutrons might bombard the nuclei of materials outside a cold fusion cell to cause nuclear reactions. In this paper, observations of nuclear emulsions that were irradiated during a cold fusion experiment with heavy water and palladium foil are described. Various traces, like stars, showing nuclear reactions caused by the multiple-neutrons have been clearly observed

A novel behavioral assay for measuring cold sensation in mice.

Directory of Open Access Journals (Sweden)

Daniel S Brenner

Full Text Available Behavioral models of cold responses are important tools for exploring the molecular mechanisms of cold sensation. To complement the currently cold behavioral assays and allow further studies of these mechanisms, we have developed a new technique to measure the cold response threshold, the cold plantar assay. In this assay, animals are acclimated on a glass plate and a cold stimulus is applied to the hindpaw through the glass using a pellet of compressed dry ice. The latency to withdrawal from the cooled glass is used as a measure of the cold response threshold of the rodents, and the dry ice pellet provides a ramping cold stimulus on the glass that allows the correlation of withdrawal latency values to rough estimates of the cold response threshold temperature. The assay is highly sensitive to manipulations including morphine-induced analgesia, Complete Freund's Adjuvant-induced inflammatory allodynia, and Spinal Nerve Ligation-induced neuropathic allodynia.

Project COLD.

Science.gov (United States)

Kazanjian, Wendy C.

1982-01-01

Describes Project COLD (Climate, Ocean, Land, Discovery) a scientific study of the Polar Regions, a collection of 35 modules used within the framework of existing subjects: oceanography, biology, geology, meterology, geography, social science. Includes a partial list of topics and one activity (geodesic dome) from a module. (Author/SK)

A novel cold-inducible zinc finger protein from soybean, SCOF-1, enhances cold tolerance in transgenic plants.

Science.gov (United States)

Kim, J C; Lee, S H; Cheong, Y H; Yoo, C M; Lee, S I; Chun, H J; Yun, D J; Hong, J C; Lee, S Y; Lim, C O; Cho, M J

2001-02-01

Cold stress on plants induces changes in the transcription of cold response genes. A cDNA clone encoding C2H2-type zinc finger protein, SCOF-1, was isolated from soybean. The transcription of SCOF-1 is specifically induced by low temperature and abscisic acid (ABA) but not by dehydration or high salinity. Constitutive overexpression of SCOF-1 induced cold-regulated (COR) gene expression and enhanced cold tolerance of non-acclimated transgenic Arabidopsis and tobacco plants. SCOF-1 localized to the nucleus but did not bind directly to either C-repeat/dehydration (CRT/DRE) or ABA responsive element (ABRE), cis-acting DNA regulatory elements present in COR gene promoters. However, SCOF-1 greatly enhanced the DNA binding activity of SGBF-1, a soybean G-box binding bZIP transcription factor, to ABRE in vitro. SCOF-1 also interacted with SGBF-1 in a yeast two-hybrid system. The SGBF-1 transactivated the beta-glucuronidase reporter gene driven by the ABRE element in Arabidopsis leaf protoplasts. Furthermore, the SCOF-1 enhanced ABRE-dependent gene expression mediated by SGBF-1. These results suggest that SCOF-1 may function as a positive regulator of COR gene expression mediated by ABRE via protein-protein interaction, which in turn enhances cold tolerance of plants.

Urofollitropin and ovulation induction

NARCIS (Netherlands)

van Wely, Madelon; Yding Andersen, Claus; Bayram, Neriman; van der Veen, Fulco

2005-01-01

Anovulation is a common cause of female infertility. Treatment for women with anovulation is aimed at induction of ovulation. Ovulation induction with follicle-stimulating hormone (FSH) is indicated in women with WHO type II anovulation in whom treatment with clomifene citrate (clomifene) has

Proceedings of the cold climate construction conference and expo

Energy Technology Data Exchange (ETDEWEB)

NONE

2008-07-01

This conference provided a forum to present innovative technologies in engineering, construction, energy efficiency, workforce productivity and several other aspects affecting cold regions. The session on winter construction featured tools techniques and technologies that maximize winter construction, with reference to the latest in cold weather construction techniques and lessons learned from the far north and south. It featured lessons on building on ice, frozen ground and permafrost. The session on sustainability addressed issues regarding sustainable design; solar, wind and geothermal systems; building envelopes that work in cold climates; and energy efficient products and techniques. The session on workforce productivity presented methods to keep the workforce warm and healthy in cold conditions; attracting and preparing foreign workers for the far north; worker productivity in a cold environment; tools, techniques and clothing to minimize the effects of cold weather; and cold weather equipment operations. Three presentations from the conference have been catalogued separately for inclusion in this database. refs., tabs., figs.

Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells.

Science.gov (United States)

Foxman, Ellen F; Storer, James A; Fitzgerald, Megan E; Wasik, Bethany R; Hou, Lin; Zhao, Hongyu; Turner, Paul E; Pyle, Anna Marie; Iwasaki, Akiko

2015-01-20

Most isolates of human rhinovirus, the common cold virus, replicate more robustly at the cool temperatures found in the nasal cavity (33-35 °C) than at core body temperature (37 °C). To gain insight into the mechanism of temperature-dependent growth, we compared the transcriptional response of primary mouse airway epithelial cells infected with rhinovirus at 33 °C vs. 37 °C. Mouse airway cells infected with mouse-adapted rhinovirus 1B exhibited a striking enrichment in expression of antiviral defense response genes at 37 °C relative to 33 °C, which correlated with significantly higher expression levels of type I and type III IFN genes and IFN-stimulated genes (ISGs) at 37 °C. Temperature-dependent IFN induction in response to rhinovirus was dependent on the MAVS protein, a key signaling adaptor of the RIG-I-like receptors (RLRs). Stimulation of primary airway cells with the synthetic RLR ligand poly I:C led to greater IFN induction at 37 °C relative to 33 °C at early time points poststimulation and to a sustained increase in the induction of ISGs at 37 °C relative to 33 °C. Recombinant type I IFN also stimulated more robust induction of ISGs at 37 °C than at 33 °C. Genetic deficiency of MAVS or the type I IFN receptor in infected airway cells permitted higher levels of viral replication, particularly at 37 °C, and partially rescued the temperature-dependent growth phenotype. These findings demonstrate that in mouse airway cells, rhinovirus replicates preferentially at nasal cavity temperature due, in part, to a less efficient antiviral defense response of infected cells at cool temperature.

γ→α′ Martensitic transformation and magnetic property of cold rolled Fe–20Mn–4Al–0.3C steel

Energy Technology Data Exchange (ETDEWEB)

Ma, Biao; Li, Changsheng, E-mail: lics@ral.neu.edu.cn; Han, Yahui; Wang, Jikai

2016-12-01

Direct γ→α′ martensitic transformation during cold rolling deformation was investigated for a high-Mn non-magnetic steel. Its influence on magnetic property was also analyzed. The magnetization under rolling reduction less than 50% almost presents a linear increase with the applied magnetic field. With deformation up to 73% and 93% thickness reductions, strain induced α′-martensite transformation starts to occur, causing the steel to be slightly magnetized. The α′-martensite prefers to nucleate directly at either microband–microband or microband-twin intersections without participation of intermediate ε-martensite. The volume fraction of α′-martensite is estimated as 0.070% and 0.17%, respectively, based on the magnetic hysteresis loops. Such a small fraction of ferromagnetic α′-martensite shows little influence on the magnetic induction intensity and low relative permeability. - Highlights: • Magnetic property of high-Mn austenitic steel was examined after cold rolling. • Nucleation mode for direct γ→α′ martensitic transformation was observed and discussed. • Volume fraction of strain induced α′-martensite was estimated by magnetic measurement.

Inducing Cold-Sensitivity in the Frigophilic Fly Drosophila montana by RNAi.

Directory of Open Access Journals (Sweden)

Felipe M Vigoder

Full Text Available Cold acclimation is a critical physiological adaptation for coping with seasonal cold. By increasing their cold tolerance individuals can remain active for longer at the onset of winter and can recover more quickly from a cold shock. In insects, despite many physiological studies, little is known about the genetic basis of cold acclimation. Recently, transcriptomic analyses in Drosophila virilis and D. montana revealed candidate genes for cold acclimation by identifying genes upregulated during exposure to cold. Here, we test the role of myo-inositol-1-phosphate synthase (Inos, in cold tolerance in D. montana using an RNAi approach. D. montana has a circumpolar distribution and overwinters as an adult in northern latitudes with extreme cold. We assessed cold tolerance of dsRNA knock-down flies using two metrics: chill-coma recovery time (CCRT and mortality rate after cold acclimation. Injection of dsRNAInos did not alter CCRT, either overall or in interaction with the cold treatment, however it did induced cold-specific mortality, with high levels of mortality observed in injected flies acclimated at 5°C but not at 19°C. Overall, injection with dsRNAInos induced a temperature-sensitive mortality rate of over 60% in this normally cold-tolerant species. qPCR analysis confirmed that dsRNA injection successfully reduced gene expression of Inos. Thus, our results demonstrate the involvement of Inos in increasing cold tolerance in D. montana. The potential mechanisms involved by which Inos increases cold tolerance are also discussed.

Center for Cold Spray Research and Development

Data.gov (United States)

Federal Laboratory Consortium — This is the only DoD facility capable of cold spray research and development, production, and field-repair. It features three stationary cold spray systems used for...

Cold shock protein YB-1 is involved in hypoxia-dependent gene transcription

International Nuclear Information System (INIS)

Rauen, Thomas; Frye, Bjoern C.; Wang, Jialin; Raffetseder, Ute; Alidousty, Christina; En-Nia, Abdelaziz; Floege, Jürgen; Mertens, Peter R.

2016-01-01

Hypoxia-dependent gene regulation is largely orchestrated by hypoxia-inducible factors (HIFs), which associate with defined nucleotide sequences of hypoxia-responsive elements (HREs). Comparison of the regulatory HRE within the 3′ enhancer of the human erythropoietin (EPO) gene with known binding motifs for cold shock protein Y-box (YB) protein-1 yielded strong similarities within the Y-box element and 3′ adjacent sequences. DNA binding assays confirmed YB-1 binding to both, single- and double-stranded HRE templates. Under hypoxia, we observed nuclear shuttling of YB-1 and co-immunoprecipitation assays demonstrated that YB-1 and HIF-1α physically interact with each other. Cellular YB-1 depletion using siRNA significantly induced hypoxia-dependent EPO production at both, promoter and mRNA level. Vice versa, overexpressed YB-1 significantly reduced EPO-HRE-dependent gene transcription, whereas this effect was minor under normoxia. HIF-1α overexpression induced hypoxia-dependent gene transcription through the same element and accordingly, co-expression with YB-1 reduced HIF-1α-mediated EPO induction under hypoxic conditions. Taken together, we identified YB-1 as a novel binding factor for HREs that participates in fine-tuning of the hypoxia transcriptome. - Highlights: • Hypoxia drives nuclear translocation of cold shock protein YB-1. • YB-1 physically interacts with hypoxia-inducible factor (HIF)-1α. • YB-1 binds to the hypoxia-responsive element (HRE) within the erythropoietin (EPO) 3′ enhancer. • YB-1 trans-regulates transcription of hypoxia-dependent genes such as EPO and VEGF.

Ionic mechanisms of spinal neuronal cold hypersensitivity in ciguatera.

Science.gov (United States)

Patel, Ryan; Brice, Nicola L; Lewis, Richard J; Dickenson, Anthony H

2015-12-01

Cold hypersensitivity is evident in a range of neuropathies and can evoke sensations of paradoxical burning cold pain. Ciguatoxin poisoning is known to induce a pain syndrome caused by consumption of contaminated tropical fish that can persist for months and include pruritus and cold allodynia; at present no suitable treatment is available. This study examined, for the first time, the neural substrates and molecular components of Pacific ciguatoxin-2-induced cold hypersensitivity. Electrophysiological recordings of dorsal horn lamina V/VI wide dynamic range neurones were made in non-sentient rats. Subcutaneous injection of 10 nm ciguatoxin-2 into the receptive field increased neuronal responses to innocuous and noxious cooling. In addition, neuronal responses to low-threshold but not noxious punctate mechanical stimuli were also elevated. The resultant cold hypersensitivity was not reversed by 6-({2-[2-fluoro-6-(trifluoromethyl)phenoxy]-2-methylpropyl}carbamoyl)pyridine-3-carboxylic acid, an antagonist of transient receptor potential melastatin 8 (TRPM8). Both mechanical and cold hypersensitivity were completely prevented by co-injection with the Nav 1.8 antagonist A803467, whereas the transient receptor potential ankyrin 1 (TRPA1) antagonist A967079 only prevented hypersensitivity to innocuous cooling and partially prevented hypersensitivity to noxious cooling. In naive rats, neither innocuous nor noxious cold-evoked neuronal responses were inhibited by antagonists of Nav 1.8, TRPA1 or TRPM8 alone. Ciguatoxins may confer cold sensitivity to a subpopulation of cold-insensitive Nav 1.8/TRPA1-positive primary afferents, which could underlie the cold allodynia reported in ciguatera. These data expand the understanding of central spinal cold sensitivity under normal conditions and the role of these ion channels in this translational rat model of ciguatoxin-induced hypersensitivity. © 2015 The Authors. European Journal of Neuroscience published by Federation of

Laser-Free Cold-Atom Gymnastics

Science.gov (United States)

Gould, Harvey; Feinberg, Benedict; Munger, Charles T., Jr.; Nishimura, Hiroshi

2017-01-01

We have performed beam transport simulations on ultra cold (2 μK) and cold (130 μK) neutral Cs atoms in the F = M = + 4 (magnetic weak-field seeking) ground state. We use inhomogeneous magnetic fields to focus and accelerate the atoms. Acceleration of neutral atoms by an inhomogeneous magnetic field was demonstrated by Stern and Gerlach in 1922. In the simulations, a two mm diameter cloud of atoms is released to fall under gravity. A magnetic coil focuses the falling atoms. After falling 41 cm, the atoms are reflected in the magnetic fringe field of a solenoid. They return to their starting height, about 0.7 s later, having passed a second time through the focusing coil. The simulations show that > 98 % of ultra cold Cs atoms and > 70 % of cold Cs atoms will survive at least 15 round trips (assuming perfect vacuum). More than 100 simulations were run to optimize coil currents and focusing coil diameter and height. Simulations also show that atoms can be launched into a fountain. An experimental apparatus to test the simulations, is being constructed. This technique may find application in atomic fountain clocks, interferometers, and gravitometers, and may be adaptable for use in microgravity. It may also work with Bose-Einstein condensates of paramagnetic atoms.

Metallization of Various Polymers by Cold Spray

Science.gov (United States)

Che, Hanqing; Chu, Xin; Vo, Phuong; Yue, Stephen

2018-01-01

Previous results have shown that metallic coatings can be successfully cold sprayed onto polymeric substrates. This paper studies the cold sprayability of various metal powders on different polymeric substrates. Five different substrates were used, including carbon fiber reinforced polymer (CFRP), acrylonitrile butadiene styrene (ABS), polyether ether ketone (PEEK), polyethylenimine (PEI); mild steel was also used as a benchmark substrate. The CFRP used in this work has a thermosetting matrix, and the ABS, PEEK and PEI are all thermoplastic polymers, with different glass transition temperatures as well as a number of distinct mechanical properties. Three metal powders, tin, copper and iron, were cold sprayed with both a low-pressure system and a high-pressure system at various conditions. In general, cold spray on the thermoplastic polymers rendered more positive results than the thermosetting polymers, due to the local thermal softening mechanism in the thermoplastics. Thick copper coatings were successfully deposited on PEEK and PEI. Based on the results, a method is proposed to determine the feasibility and deposition window of cold spraying specific metal powder/polymeric substrate combinations.

Induction immunosuppressive therapies in renal transplantation.

Science.gov (United States)

Gabardi, Steven; Martin, Spencer T; Roberts, Keri L; Grafals, Monica

2011-02-01

Induction immunosuppressive therapies for patients undergoing renal transplantation are reviewed. The goal of induction therapy is to prevent acute rejection during the early posttransplantation period by providing a high degree of immunosuppression at the time of transplantation. Induction therapy is often considered essential to optimize outcomes, particularly in patients at high risk for poor short-term outcomes. All of the induction immunosuppressive agents currently used are biological agents and are either monoclonal (muromonab-CD3, daclizumab, basiliximab, alemtuzumab) or polyclonal (antithymocyte globulin [equine] or antithymocyte globulin [rabbit]) antibodies. Although antithymocyte globulin (rabbit) is not labeled for induction therapy, it is used for this purpose more than any other agent. Basiliximab is not considered as potent an immunosuppressive agent but has a much more favorable adverse-effect profile compared with antithymocyte globulin (rabbit) and is most commonly used in patients at low risk for acute rejection. Rituximab is being studied for use as induction therapy but to date has not demonstrated any significant benefits over placebo. While head-to-head data are available comparing most induction agents, the final decision on the most appropriate induction therapy for a transplant recipient is highly dependent on preexisting medical conditions, donor characteristics, and the maintenance immunosuppressive regimen to be used. No standard induction immunosuppressive regimen exists for patients undergoing renal transplantation. Antithymocyte globulin (rabbit) is the most commonly used agent, whereas basiliximab appears safer. The choice of regimen depends on the preferences of clinicians and institutions.

A Philosophical Treatise of Universal Induction

Directory of Open Access Journals (Sweden)

Samuel Rathmanner

2011-06-01

Full Text Available Understanding inductive reasoning is a problem that has engaged mankind for thousands of years. This problem is relevant to a wide range of fields and is integral to the philosophy of science. It has been tackled by many great minds ranging from philosophers to scientists to mathematicians, and more recently computer scientists. In this article we argue the case for Solomonoff Induction, a formal inductive framework which combines algorithmic information theory with the Bayesian framework. Although it achieves excellent theoretical results and is based on solid philosophical foundations, the requisite technical knowledge necessary for understanding this framework has caused it to remain largely unknown and unappreciated in the wider scientific community. The main contribution of this article is to convey Solomonoff induction and its related concepts in a generally accessible form with the aim of bridging this current technical gap. In the process we examine the major historical contributions that have led to the formulation of Solomonoff Induction as well as criticisms of Solomonoff and induction in general. In particular we examine how Solomonoff induction addresses many issues that have plagued other inductive systems, such as the black ravens paradox and the confirmation problem, and compare this approach with other recent approaches.

Review of induction LINACS

International Nuclear Information System (INIS)

Faltens, A.; Keefe, D.

1981-10-01

There has been a recent upsurge of activity in the field of induction linacs, with several new machines becoming operational and others in the design stages. The performance levels of electron machines have reached 10's of kiloamps of current and will soon reach 10's of MeV's of energy. Acceleration of ion current has been demonstrated, and the study of a 10 GeV heavy ion induction linac for ICF continues. The operating principles of induction linacs are reviewed with the emphasis on design choices which are important for increasing the maximum beam currents

Properties of inductive reasoning.

Science.gov (United States)

Heit, E

2000-12-01

This paper reviews the main psychological phenomena of inductive reasoning, covering 25 years of experimental and model-based research, in particular addressing four questions. First, what makes a case or event generalizable to other cases? Second, what makes a set of cases generalizable? Third, what makes a property or predicate projectable? Fourth, how do psychological models of induction address these results? The key results in inductive reasoning are outlined, and several recent models, including a new Bayesian account, are evaluated with respect to these results. In addition, future directions for experimental and model-based work are proposed.

Review of induction linacs

International Nuclear Information System (INIS)

Faltens, A.; Keefe, D.

1982-01-01

There has been a recent upsurge of activity in the field of induction linacs, with several new machines becoming operational and others in the design stages. The performance levels of electron machines have reached 10's of kiloamps of current and will soon reach 10's of MeV's of energy. Acceleration of several kiloamps of ion current has been demonstrated, and the study of a 10 GeV heavy ion induction linac for ICF continues. The operating principles of induction linacs are reviewed with the emphasis on design choices which are important for increasing the maximum beam currents

CROSS-TOLERANCE MECHANISM INDUCTION IN MELON SEEDS BY PRIMING PRIOR DRYING

Directory of Open Access Journals (Sweden)

Jean Marcel Sousa Lira

2015-04-01

Full Text Available The loss of benefits after re-drying is one of the drawbacks of the seed priming technique. Different types of stresses have been used before re-drying to preserve the priming benefits. This process may be seen as promoting cross tolerance to increase the defense mechanisms that prevent loss of viability in seeds primed after drying. We tested the effect of some stresses to induce cross-tolerance and different drying conditions with the aim of maintaining priming benefits in melon seeds. The seeds were primed in an aerated KNO3 solution (0.35M, -1.7MPa, 25 °C, in the dark for six days. The primed seeds were then submitted to slow drying, fast drying, cold shock + slow drying, cold shock + fast drying, heat shock + slow drying, heat shock + fast drying, PEG + slow drying, PEG + fast drying, ABA + slow drying, ABA + fast drying and no drying (planted directly after priming. We evaluated antioxidant enzyme activities (SOD, CAT and APX, germinability, mean time of germination (MTG and mean rate of germination (MRG. A completely randomized design was used with three repetitions of 50 seeds in each treatment. Data were analyzed by ANOVA and means were compared by the Scott-Knott test (p ≤ 0.05. ABA increased SOD activity after drying and CAT activity was reduced by priming. APX activity was not observed. The stress submission prior to re-drying improved the MRG and reduced MTG. Therefore, the induction of the cross-tolerance mechanism could be effective to maintain priming benefits in melon seeds.

Cold regions isotope applications

International Nuclear Information System (INIS)

Perrigo, L.D.; Divine, T.E.

1976-04-01

Pacific Northwest Laboratories (PNL) started the Cold Regions Isotope Applications Program in FY-1975 to identify special conditions in the Arctic and similar geographic areas (Cold Regions) where radioisotope power, heater, or sterilization systems would be desirable and economically viable. Significant progress was made in the first year of this program and all objectives for this initial 12-month period were achieved. The major conclusions and recommendations resulting for this effort are described below. The areas of interest covered include: radiosterilization of sewage; heating of septic tanks; and radioisotope thermoelectric generators as power sources for meteorological instruments and navigational aids

High throughput salt separation from uranium deposits

Energy Technology Data Exchange (ETDEWEB)

Kwon, S.W.; Park, K.M.; Kim, J.G.; Kim, I.T.; Park, S.B., E-mail: swkwon@kaeri.re.kr [Korea Atomic Energy Research Inst. (Korea, Republic of)

2014-07-01

It is very important to increase the throughput of the salt separation system owing to the high uranium content of spent nuclear fuel and high salt fraction of uranium dendrites in pyroprocessing. Multilayer porous crucible system was proposed to increase a throughput of the salt distiller in this study. An integrated sieve-crucible assembly was also investigated for the practical use of the porous crucible system. The salt evaporation behaviors were compared between the conventional nonporous crucible and the porous crucible. Two step weight reductions took place in the porous crucible, whereas the salt weight reduced only at high temperature by distillation in a nonporous crucible. The first weight reduction in the porous crucible was caused by the liquid salt penetrated out through the perforated crucible during the temperature elevation until the distillation temperature. Multilayer porous crucibles have a benefit to expand the evaporation surface area. (author)

21 CFR 133.124 - Cold-pack cheese food.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Cold-pack cheese food. 133.124 Section 133.124 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD... Cheese and Related Products § 133.124 Cold-pack cheese food. (a)(1) Cold-pack cheese food is the food...

Induction generator-induction motor wind-powered pumping system

Energy Technology Data Exchange (ETDEWEB)

Miranda, M.S.; Lyra, R.O.C.; Silva, S.R. [CPDEE - UFMG, Belo Horizonte (Brazil)

1997-12-31

The energy storage matter plays an important role in wind-electric conversion systems for isolated applications. Having that in mind, two different approaches can be basically considered: either the immediate conversion of the generated electric energy, as in a water pumping system or electric energy storage for later use, as in a battery charging system. Due to some features such as no need of an external reactive power source and, sometimes, a gearbox, permanent-magnet synchronous generators have been broadly used in low rated power isolated systems. Despite that, system performance can be affected when the generator is feeding an inductive load (e.g., an induction motor) under variable-speed-variable-frequency operational conditions. Since there is no effective flux control, motor overload may occur at high wind speeds. Thus, good system performance can be obtained through additional control devices which may increase system cost. Although being rugged and cheap, induction machines always work as a reactive power drain; therefore, they demand an external reactive power source. Considering that, reactive static compensators appear as an attractive alternative to the cost x performance problem. In addition to that, different control strategies can be used so that system performance can be improved.

Cold fusion

International Nuclear Information System (INIS)

Seo, Suk Yong; You, Jae Jun

1996-01-01

Nearly every technical information is chased in the world. All of them are reviewed and analyzed. Some of them are chosen to study further more to review every related documents. And a probable suggestion about the excitonic process in deuteron absorbed condensed matter is proposed a way to cold fusion. 8 refs. (Author)

Cold dark matter from the hidden sector