COI (cytochrome oxidase-I) sequence based studies of Carangid fishes from Kakinada coast, India.

Science.gov (United States)

Persis, M; Chandra Sekhar Reddy, A; Rao, L M; Khedkar, G D; Ravinder, K; Nasruddin, K

2009-09-01

Mitochondrial DNA, cytochrome oxidase-1 gene sequences were analyzed for species identification and phylogenetic relationship among the very high food value and commercially important Indian carangid fish species. Sequence analysis of COI gene very clearly indicated that all the 28 fish species fell into five distinct groups, which are genetically distant from each other and exhibited identical phylogenetic reservation. All the COI gene sequences from 28 fishes provide sufficient phylogenetic information and evolutionary relationship to distinguish the carangid species unambiguously. This study proves the utility of mtDNA COI gene sequence based approach in identifying fish species at a faster pace.

Aproximación a la filogenia de Spodoptera (Lepidoptera: Noctuidae con el uso de un fragmento del gen de la citocromo oxidasa I (COI Approach to Spodoptera (Lepidoptera: Noctuidae phylogeny based on the sequence of the cytocrhome oxydase I (COI mitochondrial gene

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Clara Inés Saldamando

2012-09-01

Full Text Available En este trabajo se secuenció un fragmento de 451pb del gen mitocondrial de la citocromo oxidasa I (COI en 62 secuencias del género Spodoptera y una secuencia de Bombix mori (grupo externo. Los resultados mostraron gran diferenciación genética (distancia K2 entre los haplotipos de Spodoptera frugiperda de Colombia y Estados Unidos, según los estimadores de diversidad haplotípica, diversidad y polimorfismo nucleotídicos calculados. Un árbol de ML agrupó las especies con valores de bootstrap entre 73-99% en las ramas internas. No obstante algunas ramas presentaron bajos valores de bootstrap. Este árbol formó un grupo constituido por las especies del hemisferio oriental (S. littoralis y S. litura y también agrupó las especies localizadas en el hemisferio occidental (S. androgea, S. dolichos, S. eridania, S. exigua, S. frugiperda, S. latifascia, S. ornithogalli y S. pulchella. Esto demuestra que el árbol agrupó las especies con base en su origen geográfico. Contrariamente, el árbol no agrupó a S. frugiperda con S. ornithogalli, demostrando que a pesar de que ambas coexisten en el cultivo de algodón, no comparten un ancestro común reciente. En Colombia, estas especies forman parte del “complejo Spodoptera” del algodón, y nuestros resultados demuestran que la secuenciación de este gen permite diferenciarlas sin necesidad del uso de claves taxonómicas de sus estadios larvales. Este trabajo es una aproximación a la filogenia de este género, por lo cual la inclusión de más genes (mitocondriales y nucleares son necesarios para futuros trabajos.The genus Spodoptera includes 30 species of moths considered important pests worldwide, with a great representation in the Western Hemisphere. In general, Noctuidae species have morphological similarities that have caused some difficulties for assertive species identification by conventional methods. The purpose of this work was to generate an approach to the genus phylogeny from

Nuclear charge radius of $^{12}$Be

CERN Document Server

Krieger, Andreas; Bissell, Mark L; Frömmgen, Nadja; Geppert, Christopher; Hammen, Michael; Kreim, Kim; Kowalska, Magdalena; Krämer, Jörg; Neff, Thomas; Neugart, Rainer; Neyens, Gerda; Nörtershäuser, Wilfried; Novotny, Christian; Sanchez, Rodolfo; Yordanov, Deyan T

2012-01-01

The nuclear charge radius of $^{12}$Be was precisely determined using the technique of collinear laser spectroscopy on the $2s_{1/2}\\rightarrow 2p_{1/2, 3/2}$ transition in the Be$^{+}$ ion. The mean square charge radius increases from $^{10}$Be to $^{12}$Be by $\\delta ^{10,12} = 0.69(5)$ fm$^{2}$ compared to $\\delta ^{10,11} = 0.49(5)$ fm$^{2}$ for the one-neutron halo isotope $^{11}$Be. Calculations in the fermionic molecular dynamics approach show a strong sensitivity of the charge radius to the structure of $^{12}$Be. The experimental charge radius is consistent with a breakdown of the N=8 shell closure.

Craspedacusta sowerbii, Lankester 1880 – population dispersal analysis using COI and ITS sequences

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Franz BRÜMMER

2009-02-01

Full Text Available Craspedacusta sowerbii (Hydrozoa, Limnomedusae, Olindiidae is a freshwater jellyfish, which was discovered in England in 1880. Although thought to originate in South America, it became obvious that the species is native to the Yangtze River system in China. It has spread from China into lakes all over the world. Many different species, variations and sub-species have been described based on morphological characters. Specimens discovered in North America were described as separate species, as morphological differences appeared to be significant compared to European specimens. Even within Europe, differences were assumed to be obvious. Up to this point, three valid species are published; others are considered by various scientists to be true species as well, but mostly are recognized as variations. To obtain further insight into population dynamics of C. sowerbii as well as molecular information on the species itself, sequences of internal transcribed spacers (ITS and cytochrome oxidase subunit I (COI have been used to analyze specimens collected in Germany and Austria. These sequences have been compared to sequences published of different Chinese Craspedacusta species and variations. In addition, morphological descriptions were compared. For the COI sequences, we found uniformity throughout the complete set of samples. However, no comparisons could be made, as no data had been published on COI of Chinese specimens. ITS1, 5.8S and ITS2, including partial 18S and 28S, sequences, were almost uniform within the German populations, showing only minor base pair exchanges. However, comparisons to Chinese organisms indicated, that the investigated sequences of C. sowerbii from Germany and Austria are similar, although not identical in morphology, to Craspedacusta sowerbii var. kiatingi from China. Overall our data support the assumption that there are three valid species, with the possibility of C. ziguiensis being a fourth one, and several

An allele of Arabidopsis COI1 with hypo- and hypermorphic phenotypes in plant growth, defence and fertility.

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Albor Dobón

Full Text Available Resistance to biotrophic pathogens is largely dependent on the hormone salicylic acid (SA while jasmonic acid (JA regulates resistance against necrotrophs. JA negatively regulates SA and is, in itself, negatively regulated by SA. A key component of the JA signal transduction pathway is its receptor, the COI1 gene. Mutations in this gene can affect all the JA phenotypes, whereas mutations in other genes, either in JA signal transduction or in JA biosynthesis, lack this general effect. To identify components of the part of the resistance against biotrophs independent of SA, a mutagenised population of NahG plants (severely depleted of SA was screened for suppression of susceptibility. The screen resulted in the identification of intragenic and extragenic suppressors, and the results presented here correspond to the characterization of one extragenic suppressor, coi1-40. coi1-40 is quite different from previously described coi1 alleles, and it represents a strategy for enhancing resistance to biotrophs with low levels of SA, likely suppressing NahG by increasing the perception to the remaining SA. The phenotypes of coi1-40 lead us to speculate about a modular function for COI1, since we have recovered a mutation in COI1 which has a number of JA-related phenotypes reduced while others are equal to or above wild type levels.

IDENTIFICATION OF PARAMECIUM BURSARIA SYNGENS THROUGH MOLECULAR MARKERS – COMPARATIVE ANALYSIS OF MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT I (COI

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Patrycja Zagata

2014-08-01

Full Text Available The aim of this study is an identification of Paramecium bursaria syngens originating from different geographical locations and proving the correlation between distributions and belonging to any of five syngens. Ten strains of Paramecium bursaria belonging to five different syngens and strain of Paramecium multimicronucleatum were investigated using molecular marker — mitochondrial cytochrome c oxidase subunit I (COI. According to results, obtained in this study, using phylogenetic methods like Neighbor Joining (NJ and Maximum Likelihood (ML, relationship between analyzing strains through their clustering in clusters and correlation between strains belonging to any syngen and syngen’s distribution was confirmed. Phylograms constructed using NJ and ML methods revealed strains’ grouping in five clusters. Results which were obtained revealed usefulness of COI as a biomarker, which is important in identification of Paramecium bursaria syngens. This reports to a great potential of COI as a molecular marker and obtaining dependable results through combination of molecular methods with classical ones.

Phyllanthus coi (Phyllanthaceae, a new herbaceous species from the Philippines

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Ming-Jou WU

2017-11-01

Full Text Available Phyllanthus coi M.J. Wu, Ferreras & Y.J. Chen, a new species from Benguet Province, Island of Luzon, the Philippines, is described and illustrated. Compared to its congeners in the same section, P. coi can be differentiated by having long plagiotropic branchlets with up to 30 leaves per side, seeds with sharp honey-comb-like ridges on the dorsal side, and three free styles that are not lying flat on the top of the ovary. The floral, seed and some vegetative features that distinguish this new species from its nearest morphologically related species, P. erythrotrichus C.B. Rob., P. urinaria L. and P. hookeri Müll. Arg. are provided.

Observation of the exclusive nuclear excitation νe+12C→12Ng.s.+e- in the KARMEN detector

International Nuclear Information System (INIS)

Woelfle, S.

1992-10-01

This report concentrates on the exclusive nuclear excitation ν e + 12 C → 12 N g.s + e - induced by the weak charged current. This reaction is followed by 12 N-decay and has a very high signal to background ratio of 27:1 due to its sequential structure. The flux averaged cross section was measured to be =[7.9±1.1(stat)±0.7(syst)].10 -42 cm 2 . Both the good calorimetric and energy resolution properties of the KARMEN detector enabled the experiment to deduce for the first time an energy dependent cross section for this reaction. The shape and absolute value of the cross section agree well with theoretical predictions. A first search for neutrino oscillations demonstrated the feasilibity of the planned oscillation experiments. Oscillation probabilities P(ν μ →ν e ) ≥ 0.091 and P(anti ν μ →anti ν e ) ≥ 0.045 could be excluded at a 90% confidence level. Thus promising results will be expected at the end of the five years measuring period. (orig.) [de

The phylogeny of the social wasp subfamily Polistinae: evidence from microsatellite flanking sequences, mitochondrial COI sequence, and morphological characters

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Strassmann Joan E

2004-03-01

Full Text Available Abstract Background Social wasps in the subfamily Polistinae (Hymenoptera: Vespidae have been important in studies of the evolution of sociality, kin selection, and within colony conflicts of interest. These studies have generally been conducted within species, because a resolved phylogeny among species is lacking. We used nuclear DNA microsatellite flanking sequences, mitochondrial COI sequence, and morphological characters to generate a phylogeny for the Polistinae (Hymenoptera using 69 species. Results Our phylogeny is largely concordant with previous phylogenies at higher levels, and is more resolved at the species level. Our results support the monophyly of the New World subgenera of Polistini, while the Old World subgenera are a paraphyletic group. All genera for which we had more than one exemplar were supported as monophyletic except Polybia which is not resolved, and may be paraphyletic. Conclusion The combination of DNA sequences from flanks of microsatellite repeats with mtCOI sequences and morphological characters proved to be useful characters establishing relationships among the different subgenera and species of the Polistini. This is the first detailed hypothesis for the species of this important group.

High-altitude adaptation of Tibetan chicken from MT-COI and ATP-6 perspective.

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Zhao, Xiaoling; Wu, Nan; Zhu, Qing; Gaur, Uma; Gu, Ting; Li, Diyan

2016-09-01

The problem of hypoxia adaptation in high altitudes is an unsolved brainteaser in the field of life sciences. As one of the best chicken breeds with adaptability to highland environment, the Tibetan chicken, is genetically different from lowland chicken breeds. In order to gain a better understanding of the mechanism of hypoxic adaptability in high altitude, in the present study, we focused on the MT-COI together with ATP-6 gene to explore the regulatory mechanisms for hypoxia adaptability in Tibet chicken. Here, we sequenced MT-COI of 29 Tibetan chickens and 30 Chinese domestic chickens and ATP-6 gene of 28 Tibetan chickens and 29 Chinese domestic chickens. In MT-COI gene, 9 single nucleotide polymorphisms (SNPs) were detected though none of these was a missense mutation, confirming the fact that MT-COI gene is a largely conservative sequence. In ATP-6 gene, 6 single nucleotide polymorphisms (SNPs) were detected and we found a missense mutation (m.9441G > A) in the ATP-6 gene of Tibetan chicken resulting in an amino acid substitution. Due to the critical role of ATP-6 gene in the proton translocation and energy metabolism, we speculated the possibility of this mutation playing an important role in easier energy conversion and metabolism in Tibetan chickens than Chinese domestic chickens so as to better adapt to the harsh environment of the high-altitude areas. The Median-joining profile also suggested that haplotype Ha2 has the ancestral position to the other haplotypes and has significant relationship with high-altitude adaptation in ATP-6 gene. Therefore, we considered that the polymorphism (m.9441G > A) in the ATP-6 gene may affect the specific functions of ATP-6 enzyme relating to high-altitude adaptation of Tibetan chicken and MT-COI gene is a largely conservative sequence.

[Identification of common medicinal snakes in medicated liquor of Guangdong by COI barcode sequence].

Science.gov (United States)

Liao, Jing; Chao, Zhi; Zhang, Liang

2013-11-01

To identify the common snakes in medicated liquor of Guangdong using COI barcode sequence,and to test the feasibility. The COI barcode sequences of collected medicinal snakes were amplified and sequenced. The sequences combined with the data from GenBank were analyzed for divergence and building a neighbor-joining(NJ) tree with MEGA 5.0. The genetic distance and NJ tree demonstrated that there were 241 variable sites in these species, and the average (A + T) content of 56.2% was higher than the average (G + C) content of 43.7%. The maximum interspecific genetic distance was 0.2568, and the minimum was 0. 1519. In the NJ tree,each species formed a monophyletic clade with bootstrap supports of 100%. DNA barcoding identification method based on the COI sequence is accurate and can be applied to identify the common medicinal snakes.

The mitochondrial gene encoding ribosomal protein S12 has been translocated to the nuclear genome in Oenothera.

Science.gov (United States)

Grohmann, L; Brennicke, A; Schuster, W

1992-01-01

The Oenothera mitochondrial genome contains only a gene fragment for ribosomal protein S12 (rps12), while other plants encode a functional gene in the mitochondrion. The complete Oenothera rps12 gene is located in the nucleus. The transit sequence necessary to target this protein to the mitochondrion is encoded by a 5'-extension of the open reading frame. Comparison of the amino acid sequence encoded by the nuclear gene with the polypeptides encoded by edited mitochondrial cDNA and genomic sequences of other plants suggests that gene transfer between mitochondrion and nucleus started from edited mitochondrial RNA molecules. Mechanisms and requirements of gene transfer and activation are discussed. Images PMID:1454526

Molecular phylogeny of Anopheles hyrcanus group (Diptera: Culicidae) based on mtDNA COI.

Science.gov (United States)

Fang, Yuan; Shi, Wen-Qi; Zhang, Yi

2017-05-08

The Anopheles hyrcanus group, which includes at least 25 species, is widely distributed in the Oriental and Palearctic regions. Some group members have been incriminated as vectors of malaria and other mosquito-borne diseases. It is difficult to identify Hyrcanus Group members by morphological features. Thus, molecular phylogeny has been proposed as an important complementary method to traditional morphological taxonomy. Based on the GenBank database and our original study data, we used 466 mitochondrial DNA COI sequences belonging to 18 species to reconstruct the molecular phylogeny of the Hyrcanus Group across its worldwide geographic range. The results are as follows. 1) The average conspecific K2P divergence was 0.008 (range 0.002-0.017), whereas sequence divergence between congroup species averaged 0.064 (range 0.026-0.108). 2) The topology of COI tree of the Hyrcanus Group was generally consistent with classical morphological taxonomy in terms of species classification, but disagreed in subgroup division. In the COI tree, the group was divided into at least three main clusters. The first cluster contained An. nimpe; the second was composed of the Nigerrimus Subgroup and An. argyropus; and the third cluster was comprised of the Lesteri Subgroup and other unassociated species. 3) Phylogenetic analysis of COI indicated that ancient hybridizations probably occurred among the three closely related species, An. sinensis, An. belenrae, and An. kleini. 4) The results supported An. paraliae as a probable synonym of An. lesteri, and it was possible that An. pseudopictus and An. hyrcanus were the same species, as evident from their extremely low interspecific genetic divergence (0.020 and 0.007, respectively) and their phylogenetic positions. In summary, we reconstructed the molecular phylogeny and analysed genetic divergence of the Hyrcanus Group using mitochondrial COI sequences. Our results suggest that in the future of malaria surveillance, we should not only pay

Nuclear forensic analysis capabilities and experience at the Oak Ridge Y-12 National Security Complex

International Nuclear Information System (INIS)

Hembree, D.M.; Carter, J.A.; Hinton, E.R. Jr.

2002-01-01

Full text: The Oak Ridge Y-12 National Security Complex has been involved in the U.S. nuclear weapons program since the program's inception in the 1940's. Known as the U.S. 'Fort Knox of uranium', the site is also a repository of unique expertise and experience related to enriched uranium and other weapons-related materials. Y-12's Analytical Chemistry Organization (ACO) contains a wide range of analytical instrumentation that has demonstrated the ability to provide important forensic information in a short period of time. This rapid response capability is in part due to having all of the analytical instrumentation and expertise contained in one building, within one organization. Rapid-response teams are easily formed to quickly obtain key information. The infrastructure to handle nuclear materials, e.g. chain-of-custody, radiological control, information management, etc. is maintained for normal operations. As a result, the laboratory has demonstrated the capability for rapid response times for nuclear forensic samples. This poster presentation will discuss Y-12's analytical capabilities and the importance of key instruments and highly trained personnel in providing critical information. The laboratory has collaborated with both state and federal law enforcement agencies to analyze non-nuclear forensic evidence. Y-12's participation in two nuclear forensic events, as part of multi-laboratory teams, will be described. (author)

Phylogeny and species delineation in European species of the genus Steganacarus (Acari, Oribatida) using mitochondrial and nuclear markers.

Science.gov (United States)

Kreipe, Victoria; Corral-Hernández, Elena; Scheu, Stefan; Schaefer, Ina; Maraun, Mark

2015-06-01

Species of the genus Steganacarus are soil-living oribatid mites (Acari, Phthiracaridae) with a ptychoid body. The phylogeny and species status of the species of Steganacarus are not resolved, some authors group all ten German species of Steganacarus within the genus Steganacarus whereas others split them into three subgenera, Steganacarus, Tropacarus and Atropacarus. Additionally, two species, S. magnus and T. carinatus, comprise morphotypes of questionable species status. We investigated the phylogeny and species status of ten European Steganacarus species, i.e. S. applicatus, S. herculeanus, S. magnus forma magna, S. magnus forma anomala, S. spinosus, Tropacarus brevipilus, T. carinatus forma carinata, T. carinatus forma pulcherrima, Atropacarus striculus and Rhacaplacarus ortizi. We used two molecular markers, a 251 bp fragment of the nuclear gene 28S rDNA (D3) and a 477 bp fragment of the mitochondrial COI region. The phylogeny based on a combined analysis of D3 and COI separated four subgenera (Steganacarus, Tropacarus and Atropacarus, Rhacaplacarus) indicating that they form monophyletic groups. The COI region separated all ten species of the genus Steganacarus and showed variation within some species often correlating with the geographic origin of the species. Resolution of the more conserved D3 region was limited, indicating that radiation events are rather recent. Overall, our results indicate that both genes alone cannot be used for phylogeny and barcoding since variation is too low in D3 and too high in COI. However, when used in combination these genes provide reliable insight into the phylogeny, radiation and species status of taxa of the genus Steganacarus.

Phylogenetic relationships of true butterflies (Lepidoptera: Papilionoidea) inferred from COI, 16S rRNA and EF-1α sequences.

Science.gov (United States)

Kim, Man Il; Wan, Xinlong; Kim, Min Jee; Jeong, Heon Cheon; Ahn, Neung-Ho; Kim, Ki-Gyoung; Han, Yeon Soo; Kim, Iksoo

2010-11-01

The molecular phylogenetic relationships among true butterfly families (superfamily Papilionoidea) have been a matter of substantial controversy; this debate has led to several competing hypotheses. Two of the most compelling of those hypotheses involve the relationships of (Nymphalidae + Lycaenidae) + (Pieridae + Papilionidae) and (((Nymphalidae + Lycaenidae) + Pieridae) + Papilionidae). In this study, approximately 3,500 nucleotide sequences from cytochrome oxidase subunit I (COI), 16S ribosomal RNA (16S rRNA), and elongation factor-1 alpha (EF-1α) were sequenced from 83 species belonging to four true butterfly families, along with those of three outgroup species belonging to three lepidopteran superfamilies. These sequences were subjected to phylogenetic reconstruction via Bayesian Inference (BI), Maximum Likelihood (ML), and Maximum Parsimony (MP) algorithms. The monophyletic Pieridae and monophyletic Papilionidae evidenced good recovery in all analyses, but in some analyses, the monophylies of the Lycaenidae and Nymphalidae were hampered by the inclusion of single species of the lycaenid subfamily Miletinae and the nymphalid subfamily Danainae. Excluding those singletons, all phylogenetic analyses among the four true butterfly families clearly identified the Nymphalidae as the sister to the Lycaenidae and identified this group as a sister to the Pieridae, with the Papilionidae identified as the most basal linage to the true butterfly, thus supporting the hypothesis: (Papilionidae + (Pieridae + (Nymphalidae + Lycaenidae))).

Unusually high genetic diversity in COI sequences of Chimarra obscura (Trichoptera: Philopotamidae)

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Chimarra obscura (Walker 1852) is a philopotamid caddisfly found throughout much of North America. Using the COI DNA barcode locus, we have found unexpectedly high amounts of genetic diversity and distances within C. obscura. Of the approximately 150 specimens sampled, we have fo...

Genetic distance of Malaysian mousedeer based on mitochondrial DNA cytochrome oxidase I (COI) and D-loop region sequences

Science.gov (United States)

Bakar, Mohamad-Azam Akmal Abu; Rovie-Ryan, Jeffrine Japning; Ampeng, Ahmad; Yaakop, Salmah; Nor, Shukor Md; Md-Zain, Badrul Munir

2018-04-01

Mousedeer is one of the primitive mammals that can be found mainly in Southeast-Asia region. There are two species of mousedeer in Malaysia which are Tragulus kanchil and Tragulus napu. Both species can be distinguish by size, coat coloration, and throat pattern but clear diagnosis still cannot be found. The objective of the study is to show the genetic distance relationship between T. kanchil and T. napu and their population based on mitochondrial DNA (mtDNA) cytochrome oxidase I (COI) and D-loop region. There are 42 sample of mousedeer were used in this study collected by PERHILITAN from different locality. Another 29 D-loop sequence were retrieved from Genbank for comparative analysis. All sample were amplified using universal primer and species-specific primer for COI and D-loop genes via PCR process. The amplified sequences were analyzed to determine genetic distance of T. kanchil and T. napu. From the analysis, the average genetic distance between T. kanchil and T. napu based on locus COI and D-loop were 0.145 and 0.128 respectively. The genetic distance between populations of T. kanchil based on locus COI was between 0.003-0.013. For locus D-loop, genetic distance analysis showed distance in relationship between west-coast populations to east-coast population of T. kanchil. COI and D-loop mtDNA region provided a clear picture on the relationship within the mousedeer species. Last but not least, conservation effort toward protecting this species can be done by study the molecular genetics and prevent the extinction of this species.

U.S. Theater Nuclear Policy

International Nuclear Information System (INIS)

Thompson, J.A.

1994-01-01

In the brief period between May 1978 and December 12, 1979, U.S. policy, and the policy of the NATO Alliance, toward theater nuclear forces (TNF) changed dramatically. The consequences of this change now dominate the political agenda in East-West (and West-West) relations. The ultimate outcome of the now renamed intermediate-range nuclear force (INF) debate will have far-reaching consequences for the future of the Atlantic Alliance. How did this issue emerge? Why did the US change its policy? How did it work with its Alliance to change NATO policy? These questions, among others, are now figuring in the debate. The answers to these questions are discussed in detail

Nuclear EGFRvIII resists hypoxic microenvironment induced apoptosis via recruiting ERK1/2 nuclear translocation

Energy Technology Data Exchange (ETDEWEB)

Xie, Hui; Yang, Jinfeng; Xing, Wenjing; Dong, Yucui [Dept. of Immunology, Harbin Medical University, Harbin 150081 (China); Key Lab Infection & Immunity, Heilongjiang Province, Harbin 150081 (China); Ren, Huan, E-mail: renhuan@ems.hrbmu.edu.cn [Dept. of Immunology, Harbin Medical University, Harbin 150081 (China); Key Lab Infection & Immunity, Heilongjiang Province, Harbin 150081 (China)

2016-02-05

Glioblastoma (GBM) is the most aggressive type of primary brain tumor. Its interaction with the tumor microenvironment promotes tumor progression. Furthermore, GBM bearing expression of EGFRvIII displays more adaptation to tumor microenvironment related stress. But the mechanisms were poorly understood. Here, we presented evidence that in the human U87MG glioblastoma tumor model, EGFRvIII overexpression led aberrant kinase activation and nuclear translocation of EGFRvIII/ERK1/2 under hypoxia, which induced growth advantage by resisting apoptosis. Additionally, EGFRvIII defective in nuclear entry impaired this capacity in hypoxia adaptation, and partially interrupted ERK1/2 nuclear translocation. Pharmacology or genetic interference ERK1/2 decreased hypoxia resistance triggered by EGFRvIII expression, but not EGFRvIII nuclear translocation. In summary, this study identified a novel role for EGFRvIII in hypoxia tolerance, supporting an important link between hypoxia and subcellular localization alterations of the receptor. - Highlights: • Nuclear translocation of EGFRvIII contributes to GBM cell apoptotic resistance by hypoxia. • Nuclear ERK1/2 facilitates EGFRvIII in hypoxia resistance. • EGFRvIII nuclear translocation is not dependent on ERK1/2.

Characterizing the astrophysical S factor for 12C+12C fusion with wave-packet dynamics

Science.gov (United States)

Diaz-Torres, Alexis; Wiescher, Michael

2018-05-01

A quantitative study of the astrophysically important subbarrier fusion of 12C+12C is presented. Low-energy collisions are described in the body-fixed reference frame using wave-packet dynamics within a nuclear molecular picture. A collective Hamiltonian drives the time propagation of the wave packet through the collective potential-energy landscape. The fusion imaginary potential for specific dinuclear configurations is crucial for understanding the appearance of resonances in the fusion cross section. The theoretical subbarrier fusion cross sections explain some observed resonant structures in the astrophysical S factor. These cross sections monotonically decline towards stellar energies. The structures in the data that are not explained are possibly due to cluster effects in the nuclear molecule, which need to be included in the present approach.

Genetic diversity among eight Dendrolimus species in Eurasia (Lepidoptera: Lasiocampidae) inferred from mitochondrial COI and COII, and nuclear ITS2 markers.

Science.gov (United States)

Kononov, Alexander; Ustyantsev, Kirill; Wang, Baode; Mastro, Victor C; Fet, Victor; Blinov, Alexander; Baranchikov, Yuri

2016-12-22

Moths of genus Dendrolimus (Lepidoptera: Lasiocampidae) are among the major pests of coniferous forests worldwide. Taxonomy and nomenclature of this genus are not entirely established, and there are many species with a controversial taxonomic position. We present a comparative evolutionary analysis of the most economically important Dendrolimus species in Eurasia. Our analysis was based on the nucleotide sequences of COI and COII mitochondrial genes and ITS2 spacer of nuclear ribosomal genes. All known sequences were extracted from GenBank. Additional 112 new sequences were identified for 28 specimens of D. sibiricus, D. pini, and D. superans from five regions of Siberia and the Russian Far East to be able to compare the disparate data from all previous studies. In total, 528 sequences were used in phylogenetic analysis. Two clusters of closely related species in Dendrolimus were found. The first cluster includes D. pini, D. sibiricus, and D. superans; and the second, D. spectabilis, D. punctatus, and D. tabulaeformis. Species D. houi and D. kikuchii appear to be the most basal in the genus. Genetic difference among the second cluster species is very low in contrast to the first cluster species. Phylogenetic position D. tabulaeformis as a subspecies was supported. It was found that D. sibiricus recently separated from D. superans. Integration of D. sibiricus mitochondrial DNA sequences and the spread of this species to the west of Eurasia have been established as the cause of the unjustified allocation of a new species: D. kilmez. Our study further clarifies taxonomic problems in the genus and gives more complete information on the genetic structure of D. pini, D. sibiricus, and D. superans.

Candidate gene association mapping of Sclerotinia stalk rot resistance in sunflower (Helianthus annuus L.) uncovers the importance of COI1 homologs.

Science.gov (United States)

Talukder, Zahirul I; Hulke, Brent S; Qi, Lili; Scheffler, Brian E; Pegadaraju, Venkatramana; McPhee, Kevin; Gulya, Thomas J

2014-01-01

Functional markers for Sclerotinia basal stalk rot resistance in sunflower were obtained using gene-level information from the model species Arabidopsis thaliana. Sclerotinia stalk rot, caused by Sclerotinia sclerotiorum, is one of the most destructive diseases of sunflower (Helianthus annuus L.) worldwide. Markers for genes controlling resistance to S. sclerotiorum will enable efficient marker-assisted selection (MAS). We sequenced eight candidate genes homologous to Arabidopsis thaliana defense genes known to be associated with Sclerotinia disease resistance in a sunflower association mapping population evaluated for Sclerotinia stalk rot resistance. The total candidate gene sequence regions covered a concatenated length of 3,791 bp per individual. A total of 187 polymorphic sites were detected for all candidate gene sequences, 149 of which were single nucleotide polymorphisms (SNPs) and 38 were insertions/deletions. Eight SNPs in the coding regions led to changes in amino acid codons. Linkage disequilibrium decay throughout the candidate gene regions declined on average to an r (2) = 0.2 for genetic intervals of 120 bp, but extended up to 350 bp with r (2) = 0.1. A general linear model with modification to account for population structure was found the best fitting model for this population and was used for association mapping. Both HaCOI1-1 and HaCOI1-2 were found to be strongly associated with Sclerotinia stalk rot resistance and explained 7.4 % of phenotypic variation in this population. These SNP markers associated with Sclerotinia stalk rot resistance can potentially be applied to the selection of favorable genotypes, which will significantly improve the efficiency of MAS during the development of stalk rot resistant cultivars.

Insight into the Migration Routes of Plutella xylostella in China Using mtCOI and ISSR Markers

Science.gov (United States)

Tian, Lixia; Xu, Baoyun; Xie, Wen; Wang, Shaoli; Zhang, Youjun; Wang, Xiangjing; Wu, Qingjun

2015-01-01

The larvae of the diamondback moth, Plutella xylostella, cause major economic losses to cruciferous crops, including cabbage, which is an important vegetable crop in China. In this study, we used the mitochondrial COI gene and 11 ISSR markers to characterize the genetic structure and seasonal migration routes of 23 P. xylostella populations in China. Both the mitochondrial and nuclear markers revealed high haplotype diversity and gene flow among the populations, although some degree of genetic isolation was evident between the populations of Hainan Island and other sampling sites. The dominant haplotypes, LX1 and LX2, differed significantly from all other haplotypes both in terms of the number of individuals with those haplotypes and their distributions. Haplotypes that were shared among populations revealed that P. xylostella migrates from the lower reaches of the Yangtze River to northern China and then to northeastern China. Our results also revealed another potential migration route for P. xylostella, i.e., from southwestern China to both northwestern and southern China. PMID:26098353

Molecular phylogeny of elasmobranchs inferred from mitochondrial and nuclear markers.

Science.gov (United States)

Pavan-Kumar, A; Gireesh-Babu, P; Babu, P P Suresh; Jaiswar, A K; Hari Krishna, V; Prasasd, K Pani; Chaudhari, Aparna; Raje, S G; Chakraborty, S K; Krishna, Gopal; Lakra, W S

2014-01-01

The elasmobranchs (sharks, rays and skates) being the extant survivors of one of the earliest offshoots of the vertebrate evolutionary tree are good model organisms to study the primitive vertebrate conditions. They play a significant role in maintaining the ecological balance and have high economic value. Due to over-exploitation and illegal fishing worldwide, the elasmobranch stocks are being decimated at an alarming rate. Appropriate management measures are necessary for restoring depleted elasmobranch stocks. One approach for restoring stocks is implementation of conservation measures and these measures can be formulated effectively by knowing the evolutionary relationship among the elasmobranchs. In this study, a total of 30 species were chosen for molecular phylogeny studies using mitochondrial cytochrome c oxidase subunit I, 12S ribosomal RNA gene and nuclear Internal Transcribed Spacer 2. Among different genes, the combined dataset of COI and 12S rRNA resulted in a well resolved tree topology with significant bootstrap/posterior probabilities values. The results supported the reciprocal monophyly of sharks and batoids. Within Galeomorphii, Heterodontiformes (bullhead sharks) formed as a sister group to Lamniformes (mackerel sharks): Orectolobiformes (carpet sharks) and to Carcharhiniformes (ground sharks). Within batoids, the Myliobatiformes formed a monophyly group while Pristiformes (sawfishes) and Rhinobatiformes (guitar fishes) formed a sister group to all other batoids.

Le nouveau modèle québécois axé sur la gouvernance

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Jeffrey Roy

2002-10-01

Full Text Available L'article soutient qu'il a bien eu un modèle québécois de développement, mais il est devenu inefficace et remis en question. Ce modèle se distinguait par son interventionniste étatique dynamique et par la constitution d'alliances entre les différents partenaires sociaux. Mais les fondements d'un modèle performant tels que l'étatisme et le nationalisme civique sont devenus empreints de faiblesses et d'insuffisances que l'utilisation du concept de gouvernance permet d'identifier. Le concept se définit comme étant « la coordination efficace de l'ensemble des activités d'une entité socio-économico-politique quand les ressources, le pouvoir et l'information sont vastement distribués ». Malgré l'inefficacité décrite, il est possible de repenser le modèle québécois de développement par la construction des communautés qui s'appuie sur la régionalité et la socialité. Finalement, le renouveau s'appuierait sur une stratégie de-gouvernance pour un meilleur usage de l'intelligence collective et des cités-régions intelligentes.The article supports that it indeed had a Quebecois model of development, but it became ineffective and questioned. This model distinguished itself by his(her dynamic state interventionist and by the constitution of alliances among the various social partners. But the foundations of a successful model such as the state control and the civil nationalism became printed by weaknesses and by incapacities which the use of the concept of governance allows to identify. The concept defines itself as being « the effective coordination of all the activities of an entity « socio-économico-politique » when the resources, the power and the information are distributed spaciously » Meanwhile the described ineffectiveness, it is possible to rethink the Quebecois model of development by the construction of the communities which leans on the regionality and the sociality. Finally, the flourish would lean on a strategy

Delimiting the species Neosiphonia yendoi (Rhodomelaceae, Rhodophyta) based on COI and rbcL genetic variation in Korea and Japan

Science.gov (United States)

Kim, Byeongseok; Yang, Mi Yeon; Kim, Myung Sook

2016-09-01

Although the marine red algal genus Neosiphonia is well characterized, many species of Neosiphonia are poorly understood. To correctly define the species delimitation of Neosiphonia yendoi using genetic variation, owing to the confusion over identification with " N. sphaerocarpa" from Korea, we investigated intensively the haplotype network of the mitochondrial COI and the plastid rbcL genes of specimens collected from Korea and Japan. The molecular analyses indicated that specimens collected in different sites of Korea and Japan belong to the same species, Neosiphonia yendoi and " Neosiphonia sphaerocarpa" from Korea, which is distinguished from N. sphaerocarpa from Florida and is allied with N. yendoi collected from the type locality, Muroran of Japan. A total of 29 COI and 13 rbcL haplotypes were found and the COI haplotype network shows evidence of a clear break between specimens from Jeju Island and all other locations of Korea, suggesting the possibility of cryptic diversity within N. yendoi.

Quantum correlations in a system of nuclear s = 1/2 spins in a strong magnetic field

International Nuclear Information System (INIS)

Fel’dman, E B; Kuznetsova, E I; Yurishchev, M A

2012-01-01

Entanglement and quantum discord for a pair of nuclear spins s = 1/2 in a nanopore filled with a gas of spin-carrying molecules (atoms) are studied. The correlation functions describing dynamics of dipolar-coupled spins in a nanopore are found. The dependence of spin-pair entanglement on the temperature and the number of spins is obtained from the reduced density matrix, which is centrosymmetric (CS). An analytic expression for the concurrence is obtained for an arbitrary CS density matrix. It is shown that the quantum discord as a measure of quantum correlations attains a significant value at low temperatures. It is also shown that the discord in the considered model has ‘flickering’ character and disappears periodically in the course of time evolution of the system. The geometric discord is studied for arbitrary 4 × 4 CS density matrices. (paper)

SN 2016coi/ASASSN-16fp: An example of residual helium in a type Ic supernova?

Science.gov (United States)

Prentice, S. J.; Ashall, C.; Mazzali, P. A.; Zhang, J.-J.; James, P. A.; Wang, X.-F.; Vinkó, J.; Percival, S.; Short, L.; Piascik, A.; Huang, F.; Mo, J.; Rui, L.-M.; Wang, J.-G.; Xiang, D.-F.; Xin, Y.-X.; Yi, W.-M.; Yu, X.-G.; Zhai, Q.; Zhang, T.-M.; Hosseinzadeh, G.; Howell, D. A.; McCully, C.; Valenti, S.; Cseh, B.; Hanyecz, O.; Kriskovics, L.; Pál, A.; Sárneczky, K.; Sódor, Á.; Szakáts, R.; Székely, P.; Varga-Verebélyi, E.; Vida, K.; Bradac, M.; Reichart, D. E.; Sand, D.; Tartaglia, L.

2018-05-01

The optical observations of Ic-4 supernova (SN) 2016coi/ASASSN-16fp, from ˜2 to ˜450 days after explosion, are presented along with analysis of its physical properties. The SN shows the broad lines associated with SNe Ic-3/4 but with a key difference. The early spectra display a strong absorption feature at ˜5400 Åwhich is not seen in other SNe Ic-3/4 at this epoch. This feature has been attributed to HeIin the literature. Spectral modelling of the SN in the early photospheric phase suggests the presence of residual He in a C/O dominated shell. However, the behaviour of the HeIlines is unusual when compared with He-rich SNe, showing relatively low velocities and weakening rather than strengthening over time. The SN is found to rise to peak ˜16 d after core-collapse reaching a bolometric luminosity of Lp ˜ 3 × 1042 erg s-1. Spectral models, including the nebular epoch, show that the SN ejected 2.5 - 4 M⊙of material, with ˜1.5 M⊙below 5000 km s-1, and with a kinetic energy of (4.5 - 7) × 1051 erg. The explosion synthesised ˜0.14 M⊙of 56Ni. There are significant uncertainties in E(B - V)host and the distance however, which will affect Lp and MNi. SN 2016coi exploded in a host similar to the Large Magellanic Cloud (LMC) and away from star-forming regions. The properties of the SN and the host-galaxy suggest that the progenitor had MZAMS of 23 - 28 M⊙and was stripped almost entirely down to its C/O core at explosion.

Insight into the Migration Routes of Plutella xylostella in China Using mtCOI and ISSR Markers.

Directory of Open Access Journals (Sweden)

Jiaqiang Yang

Full Text Available The larvae of the diamondback moth, Plutella xylostella, cause major economic losses to cruciferous crops, including cabbage, which is an important vegetable crop in China. In this study, we used the mitochondrial COI gene and 11 ISSR markers to characterize the genetic structure and seasonal migration routes of 23 P. xylostella populations in China. Both the mitochondrial and nuclear markers revealed high haplotype diversity and gene flow among the populations, although some degree of genetic isolation was evident between the populations of Hainan Island and other sampling sites. The dominant haplotypes, LX1 and LX2, differed significantly from all other haplotypes both in terms of the number of individuals with those haplotypes and their distributions. Haplotypes that were shared among populations revealed that P. xylostella migrates from the lower reaches of the Yangtze River to northern China and then to northeastern China. Our results also revealed another potential migration route for P. xylostella, i.e., from southwestern China to both northwestern and southern China.

Haplotype Diversity of COI Gene of Hylarana chalconota Species Found at State University of Malang

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Dian Ratri Wulandari

2014-01-01

Full Text Available Hylarana chalconota is a cryptic species of frog endemic to Java Island [1]. This species is small with long legs, and brown skin. The Snout-Vent Length (SVL ranges between 30-40 mm for male and 45-65 mm for female. [4] Reports the existence of this species in State University of Malang, which was not found in 1995 [5]. Sampel #1 displays spots in its skin, which does not exist in sample #2. To reveal the haplotype diversity of COI gene in this species, we analyzed Cytochrome-c oxidase subunit-1 (COI sequences of both samples. Using a pair of primers according to [6] both samples had 604 bp and 574 bp fragment length, respectively. These fragments showed polymorphism; with mutation position in sites 104, 105, and 124. Based on this result, we suggest that the two samples share a different haplotypes, proposed as UM1 and UM2.

Red de Repositorios IODE/COI/Unesco de acceso abierto en Ciencias Marinas en América Latina y el Caribe: OceanDocs

Directory of Open Access Journals (Sweden)

Andrea Cristiani

2014-03-01

Full Text Available Se presenta la organización, funciones y evolución de la red de repositorios de acceso abierto OceanDocs, particularmente la experiencia de instituciones vinculadas a las Ciencias Marinas en América Latina y el Caribe. En el marco de las Redes de Datos e Información Oceanográfica de la Comisión Oceanográfica Intergubernamental (COI de UNESCO, surgieron iniciativas de repositorios locales y regionales, que más tarde se consolidan y dan lugar a la red internacional de repositorios en Ciencias Marinas:  OceanDocs. En la actualidad esta red está integrada por repositorios institucionales, repositorios regionales y un repositorio central alojado por la COI. OceanDocs cuenta con políticas comunes definidas, un Grupo Directivo conformado por especialistas de distintas áreas que planifica y establece las directrices para la red, coordinadores nacionales y regionales, Unidades de Información a nivel institucional responsables de la carga de documentos, y una creciente comunidad de usuarios a nivel global.

Participer à l’évolution du modèle québécois

Directory of Open Access Journals (Sweden)

Manuel Dussault

2002-10-01

Full Text Available Ce court texte vise à expliquer la position de l’Association des manufacturiers et exportateurs du Québec (AMEQ sur la question du modèle québécois. Pour l’association, il existe un modèle québécois, comme il existe un modèle français, américain, japonais ou autres. Ce modèle, ni tout a fait original, ni tout à fait pareil aux autres, est à la fois libéral et social démocratique. Il se caractérise par le nationalisme, l’équité et la concertation. L’histoire économique moderne est devenue, en partie celle du rôle de l’État par les leviers économiques qu’il a mis en place depuis la révolution tranquille. Le modèle québécois a permis le rattrapage sur l’Ontario mais, en même temps, n’a pas réussi à abaisser son taux de chômage au niveau de la moyenne canadienne. Et après mûres réflexion, l’AMEQ est d’avis que la solution ne se trouve pas dans l’adoption d’éléments issus du modèle américain. Mais, le renouveau du modèle passe par la contribution de la société civile et non seulement par des solutions étatiques, marchandes ou encore de la concertation institutionnaliséeThis short text aims at explaining the position of the Association of the manufacturers and exporters of Quebec (AMEQ on the question of the Quebecois model. For the association, there is a Quebecois model, as there is a French, American, Japanese model or other. This model, neither everything made original, nor the completely similar to the others, is liberal and social at the same moment democratic. It is characterized by the nationalism, the equity and the dialogue. The modern economic story, partially that of the role of the state by the economic control levers which it set up since the “Révolution tranquille”. The Quebecois model allowed the picking up on Ontario but, at the same time, did not manage to lower its unemployment rate at the level of the Canadian avarage. And after reflection, the AMEQ is of

ELECNUC. Nuclear power plants in the world - 2016 edition. Status on 12-31-2015. Draft using the IAEA's PRIS database and specific I-tese studies

International Nuclear Information System (INIS)

2016-01-01

The year 2015 showed a strong dynamism with 8 new operational reactors (7.7 GWe). This trend is expected to be continued in 2016. 8 projects entered the building phase (8.4 GWe). Both newly in-operation and building reactors remain mainly pulled by China and to a lower extend by the rest of Asia. Japan confirms its nuclear program. Two of the reactors which were shut down after the Fukushima accident have been allowed to be operated again. About twenty others still go through the regulatory process. However 5 reactors faced a definitive shutdown. Assessing global installed capacity: For the second consecutive year the worldwide installed capacity increases. It reached a new maximum with 383 GWe on the 2015/12/31 (+1 GWe compared to 2011/12/31). Contents: 2015 highlights, Main characteristics of reactor types, Map of the French nuclear power plants on 01/01/2015, Worldwide status of nuclear power plants (12/31/2015), Units distributed by countries, Nuclear power plants connected to the Grid- by reactor type groups (12/31/2015), Nuclear power plants under construction on 2015, Evolution of nuclear power plants capacities connected to the grid, First electric generations supplied by a nuclear unit in each country, Electricity generation from nuclear power plants by country at the end of 2015, Evolution of the generation indicators worldwide by type, Performance indicator of French PWR units, Main nuclear operator ranking according to their installed capacity, Units connected to the grid by countries at 12/31/2015, Nuclear power plants under construction at 12/31/2015, Shutdown reactors, Exported nuclear capacity in net MWe, Exported and national nuclear capacity connected to the grid, Exported nuclear power plants under construction, Exported and national nuclear capacity under construction, Nuclear power plants planned at 12/31/2015, Appendix: Historical development, Meaning of the used acronyms, Glossary

Elecnuc. Nuclear power plants in the world - 2017 edition. Status on 12-31-2016. Draft using the IAEA's PRIS database and specific I-tese studies

International Nuclear Information System (INIS)

2017-01-01

Following the previous trend, the year 2016 showed a strong dynamism with 10 new operational reactors (10.6 GWe), only 4 other being shutdown (2.0 GWe). The number of projects entering the building phase is smaller than usual (three projects, 3.0 GWe), still leaving the pool of currently under construction reactors above 60 units. Both newly in-operation and building reactors remain mainly pulled by China and to a lower extend by the rest of Asia. Japan confirms its nuclear program, and four nuclear reactors are operating again. Assessing global installed capacity. For the third consecutive year, the worldwide installed capacity increases. It reached a new maximum with 389 GWe on the 2015/12/31 (+6 GWe compared to the 2016/12/31). Nuclear electrical production increases by 1.5%, almost reaching 18.000 TWh. The nuclear share remains around 10% of the total electricity produced. Contents: 2016 highlights, Main characteristics of reactor types, Map of the French nuclear power plants on 01/01/2016, Worldwide status of nuclear power plants (12/31/2016), Units distributed by countries, Nuclear power plants connected to the Grid- by reactor type groups (12/31/2016), Nuclear power plants under construction on 2016, Evolution of nuclear power plants capacities connected to the grid, First electric generations supplied by a nuclear unit in each country, Electricity generation from nuclear power plants by country at the end of 2016, Evolution of the generation indicators worldwide by type, Performance indicator of French PWR units, Main nuclear operator ranking according to their installed capacity, Units connected to the grid by countries at 12/31/2016, Nuclear power plants under construction at 12/31/2016, Shutdown reactors, Exported nuclear capacity in net MWe, Exported and national nuclear capacity connected to the grid, Exported nuclear power plants under construction, Exported and national nuclear capacity under construction, Nuclear power plants planned at 12

Human TRMU encoding the mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase is a putative nuclear modifier gene for the phenotypic expression of the deafness-associated 12S rRNA mutations

International Nuclear Information System (INIS)

Yan Qingfeng; Bykhovskaya, Yelena; Li Ronghua; Mengesha, Emebet; Shohat, Mordechai; Estivill, Xavier; Fischel-Ghodsian, Nathan; Guan Minxin

2006-01-01

Nuclear modifier genes have been proposed to modulate the phenotypic manifestation of human mitochondrial 12S rRNA A1491G mutation associated with deafness in many families world-wide. Here we identified and characterized the putative nuclear modifier gene TRMU encoding a highly conserved mitochondrial protein related to tRNA modification. A 1937 bp TRMU cDNA has been isolated and the genomic organization of TRMU has been elucidated. The human TRMU gene containing 11 exons encodes a 421 residue protein with a strong homology to the TRMU-like proteins of bacteria and other homologs. TRMU is ubiquitously expressed in various tissues, but abundantly in tissues with high metabolic rates including heart, liver, kidney, and brain. Immunofluorescence analysis of human 143B cells expressing TRMU-GFP fusion protein demonstrated that the human Trmu localizes and functions in mitochondrion. Furthermore, we show that in families with the deafness-associated 12S rRNA A1491G mutation there is highly suggestive linkage and linkage disequilibrium between microsatellite markers adjacent to TRMU and the presence of deafness. These observations suggest that human TRMU may modulate the phenotypic manifestation of the deafness-associated mitochondrial 12S rRNA mutations

The jasmonate receptor COI1 plays a role in jasmonate-induced lateral root formation and lateral root positioning in Arabidopsis thaliana.

Science.gov (United States)

Raya-González, Javier; Pelagio-Flores, Ramón; López-Bucio, José

2012-09-15

Jasmonic acid (JA) regulates a broad range of plant defense and developmental responses. COI1 has been recently found to act as JA receptor. In this report, we show that low micromolar concentrations of JA inhibited primary root (PR) growth and promoted lateral root (LR) formation in Arabidopsis wild-type (WT) seedlings. It was observed that the coi1-1 mutant was less sensitive to JA on pericycle cell activation to induce lateral root primordia (LRP) formation and presented alterations in lateral root positioning and lateral root emergence on bends. To investigate JA-auxin interactions important for remodeling of root system (RS) architecture, we tested the expression of auxin-inducible markers DR5:uidA and BA3:uidA in WT and coi1-1 seedlings in response to indole-3-acetic acid (IAA) and JA and analyzed the RS architecture of a suite of auxin-related mutants under JA treatments. We found that JA did not affect DR5:uidA and BA3:uidA expression in WT and coi1-1 seedlings. Our data also showed that PR growth inhibition in response to JA was likely independent of auxin signaling and that the induction of LRP required ARF7, ARF19, SLR, TIR1, AFB2, AFB3 and AXR1 loci. We conclude that JA regulation of postembryonic root development involves both auxin-dependent and independent mechanisms. Copyright © 2012 Elsevier GmbH. All rights reserved.

Testing the potential of a ribosomal 16S marker for DNA metabarcoding of insects

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Vasco Elbrecht

2016-04-01

Full Text Available Cytochrome c oxidase I (COI is a powerful marker for DNA barcoding of animals, with good taxonomic resolution and a large reference database. However, when used for DNA metabarcoding, estimation of taxa abundances and species detection are limited due to primer bias caused by highly variable primer binding sites across the COI gene. Therefore, we explored the ability of the 16S ribosomal DNA gene as an alternative metabarcoding marker for species level assessments. Ten bulk samples, each containing equal amounts of tissue from 52 freshwater invertebrate taxa, were sequenced with the Illumina NextSeq 500 system. The 16S primers amplified three more insect species than the Folmer COI primers and amplified more equally, probably due to decreased primer bias. Estimation of biomass might be less biased with 16S than with COI, although variation in read abundances of two orders of magnitudes is still observed. According to these results, the marker choice depends on the scientific question. If the goal is to obtain a taxonomic identification at the species level, then COI is more appropriate due to established reference databases and known taxonomic resolution of this marker, knowing that a greater proportion of insects will be missed using COI Folmer primers. If the goal is to obtain a more comprehensive survey the 16S marker, which requires building a local reference database, or optimised degenerated COI primers could be more appropriate.

Better Oversight Needed for Safety and Health Activities at DOE’s Nuclear Facilities.

Science.gov (United States)

1981-08-04

States Acca !3ion Tor Kl. ; BRA&I DTIC TAi \\ • inounced Jusl Lfii I "• ’ DiStril on/ r\\ D i Avai3 i - ’•ity Coi a j...m*d——I—^1 I —* Even DOE’s audit report tracking system failed to adequately document corrective actions taken or planned. This system was...designed by DOE to ensure that corrective actions on audit report recommendations are responsive, timely and complete. Audit re- ports, such as ours

Spider mite (Acari: Tetranychidae) mitochondrial COI phylogeny reviewed: host plant relationships, phylogeography, reproductive parasites and barcoding

NARCIS (Netherlands)

Ros, V.I.D.; Breeuwer, J.A.J.

2007-01-01

The past 15 years have witnessed a number of molecular studies that aimed to resolve issues of species delineation and phylogeny of mites in the family Tetranychidae. The central part of the mitochondrial COI region has frequently been used for investigating intra- and interspecific variation. All

Highlights of the 12th International Conference on Nuclear Cardiology and Cardiac CT.

Science.gov (United States)

Kitsiou, Anastasia; Dorbala, Sharmila; Scholte, Arthur J H A

2015-09-01

The 12th International Conference on Nuclear Cardiology and Cardiac CT was held from 3 to 5 May 2015 in Madrid, Spain. In this article, the three Congress Program Committee Chairs summarize selected highlights of the presented abstracts. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: journals.permissions@oup.com. This article is being published concurrently in the Journal of Nuclear Cardiology (10.1007/s12350-015-0260-y) and European Heart Journal – Cardiovascular Imaging (10.1093/ehjci/jev179). The articles are identical except for minor stylistic and spelling differences in keeping with each journal’s style. Either citation can be used when citing this article.

Nuclear Engineering Education in Support of Thailand’s Nuclear Power Programme

International Nuclear Information System (INIS)

Chanyotha, S.; Pengvanich, P.; Nilsuwankosit, S.

2015-01-01

This paper aims to introduce the nuclear engineering education at the Department of Nuclear Engineering, Chulalongkon University, Bangkok Thailand. The department has been offering curriculum in nuclear engineering to support the national nuclear power programme since 1970s. It is the oldest established nuclear engineering educational programme in the South East Asia region. Nevertheless, since the nuclear power programme has been postponed several times due to various reasons, the educational programme at the department has been continuously adapted to meet the nation’s needs. Several areas of study have been introduced, including nuclear power engineering, industrial applications of radioisotope, nuclear instrumentation, radioisotope production, radiation processing, environment and safety, nuclear materials, as well as the newly created nuclear security and non-proliferation. With the renewed interest in using nuclear power in Thailand in 2007, the department has been actively assisting both the government and the electric utility in preparing human resources to support the nuclear power programme through various educational and training modules. Realizing the importance of establishing and balancing all 3 aspects of the nuclear 3S (safety, security and safeguard) in Thailand and in the Southeast Asian region. The new curriculum of nuclear security and safeguard programme has been offered since 2013. Since the establishment, the department has produced hundreds of graduates (Diploma, Master’s, and Ph.D. levels) to feed the continuously expanding Thai nuclear industry. The full paper will provide detailed information of the curriculum, the challenges and obstacles that the department has encountered, as well as the national and international linkages which have been established over the years. (author)

Proceedings of the Canadian Nuclear Society 12. annual conference

International Nuclear Information System (INIS)

1991-01-01

This volume contains the Proceedings of the seventeen Technical Sessions from the Twelfth Annual Conference of the Canadian Nuclear Society held in Saskatoon, Saskatchewan, June 9 to 12, 1991. As in previous years, the Annual Conference of the Canadian Nuclear Society was held in conjunction with the Annual Conference of the Canadian Nuclear Association. The major topics of discussion included: reactor physics; thermal hydraulics; industrial irradiation; computer applications; fuel channel analysis; small reactors; severe accidents; fuel behaviour under accident conditions; reactor components; safety related computer software; nuclear fuel management; nuclear waste management; and, uranium mining processing

Aproximación a la filogenia de Spodoptera (Lepidoptera: Noctuidae con el uso de un fragmento del gen de la citocromo oxidasa I (COI

Directory of Open Access Journals (Sweden)

Clara Inés Saldamando

2012-09-01

Full Text Available En este trabajo se secuenció un fragmento de 451pb del gen mitocondrial de la citocromo oxidasa I (COI en 62 secuencias del género Spodoptera y una secuencia de Bombix mori (grupo externo. Los resultados mostraron gran diferenciación genética (distancia K2 entre los haplotipos de Spodoptera frugiperda de Colombia y Estados Unidos, según los estimadores de diversidad haplotípica, diversidad y polimorfismo nucleotídicos calculados. Un árbol de ML agrupó las especies con valores de bootstrap entre 73-99% en las ramas internas. No obstante algunas ramas presentaron bajos valores de bootstrap. Este árbol formó un grupo constituido por las especies del hemisferio oriental (S. littoralis y S. litura y también agrupó las especies localizadas en el hemisferio occidental (S. androgea, S. dolichos, S. eridania, S. exigua, S. frugiperda, S. latifascia, S. ornithogalli y S. pulchella. Esto demuestra que el árbol agrupó las especies con base en su origen geográfico. Contrariamente, el árbol no agrupó a S. frugiperda con S. ornithogalli, demostrando que a pesar de que ambas coexisten en el cultivo de algodón, no comparten un ancestro común reciente. En Colombia, estas especies forman parte del “complejo Spodoptera” del algodón, y nuestros resultados demuestran que la secuenciación de este gen permite diferenciarlas sin necesidad del uso de claves taxonómicas de sus estadios larvales. Este trabajo es una aproximación a la filogenia de este género, por lo cual la inclusión de más genes (mitocondriales y nucleares son necesarios para futuros trabajos.

ELECNUC. Nuclear power plants in the world - 2012 edition, Status on 2011-12-31

International Nuclear Information System (INIS)

2012-01-01

This small booklet summarizes in tables all data relative to the nuclear power plants worldwide. Data come from the IAEA's PRIS database and from specific I-tese studies. The following aspects are reviewed: 2011 highlights; Main characteristics of reactor types; Map of the French nuclear power plants on 2011/01/01; Worldwide status of nuclear power plants (12/31/2011); Units distributed by countries; Nuclear power plants connected to the Grid- by reactor type groups; Nuclear power plants under construction on 2011; Evolution of nuclear power plants capacities connected to the grid; First electric generations supplied by a nuclear unit in each country; Electrical generation from nuclear powe plants by country at the end 2011; Performance indicator of french PWR units; Evolution of the generation indicators worldwide by type; Nuclear operator ranking according to their installed capacity; Units connected to the grid by countries at 12/31/2011; Status of licence renewal applications in USA; Nuclear power plants under construction at 12/31/2011; Shutdown reactors; Exported nuclear capacity in net MWe; Exported and national nuclear capacity connected to the grid; Exported nuclear power plants under construction; Exported and national nuclear capacity under construction; Nuclear power plants ordered at 12/31/2011; Long term shutdown units at 12/31/2011; COL (Combined Licence) applications in the USA; Recycling of Plutonium in reactors and experiences; Mox licence plants projects; Appendix - historical development; Meaning of the used acronyms; Glossary

New U. S. domestic nuclear policy

Energy Technology Data Exchange (ETDEWEB)

von Welck, S

1981-12-01

On October 8, 1981, almost exactly four and a half years after President Carter's consequential Nuclear Power Policy Statement, the U.S. Secretary of Energy announced the statement on U.S. domestic nuclear policy of President Reagan, which had been expected for some time already. That statement supplements the July 16, 1981 statement on U.S. nuclear nonproliferation and export policies and the National Energy Policy Plan of the Department of Energy of July 1981. President Reagan's October 8, 1981 statement is aimed at reviving U.S. nuclear industry and achieving increasing contributions of nuclear power towards ensuring the continuity of energy supply in the USA. This includes improvements in the financial situation of the utilities, deregulation to curb unnecessary government interference, resumption of the breeder program and commercial reprocessing, and the demand to find solutions for the disposial of radioactive waste.

ELECNUC. Nuclear power plants in the world - 2015 edition. Status on 12-31-2014, Draft using the IAEA's PRIS database and specific I-tese studies

International Nuclear Information System (INIS)

2015-10-01

The situation in Japan has not evolved significantly since 2012: all its nuclear power plants are idle and safety improvements are being carried out. Several plants, however, are going through the regulatory process required to restart - the first to be implemented are expected in 2015. Few projects have been reported to be in the building phase (programs in the United Arab Emirates and in Belarus proceed), but the CAREM25 project is significant as it is the first SMR (Small Modular Reactor) to be built in the world. There is still a considerable number of ongoing building programs - i.e. more than 60 units. The commercial start of 7 reactors in China and 1 reactor in India - all of which are PWR -, offsets the decrease in installed capacity which began in 2011. This capacity increase (up 6.3 GWe) leads to an increase in nuclear electricity production (up 60 TWh). Considering the ongoing programs this trend should persist, as more than 5 commercial starts are expected each year for the next 3 years. Content: 1 - 2014 highlights; 2 - Main characteristics of reactor types; 3 - Map of the French nuclear power plants on 01/01/2014; 4 - Worldwide status of nuclear power plants (12/31/2014); 5 - Units distributed by countries; 6 - Nuclear power plants connected to the Grid- by reactor type groups (12/31/2014); 7 - Nuclear power plants under construction on 2014; 8 - Evolution of nuclear power plants capacities connected to the grid; 9 - First electric generations supplied by a nuclear unit in each country; 10 - Electricity generation from nuclear power plants by country at the end of 2014; 11 - Evolution of the generation indicators worldwide by type; 12 - Performance indicator of french PWR units; 13 - Main nuclear operator ranking according to their installed capacity; 14 - Units connected to the grid by countries at 12/31/2014; 15 - Nuclear power plants under construction at 12/31/2014; 16 - Shutdown reactors; 17 - Exported nuclear capacity in net MWe; 18 - Exported

1985 nuclear budget requests up 12 %

International Nuclear Information System (INIS)

Anon.

1984-01-01

The estimates of government agencies for the fiscal 1985 nuclear-related budget were presented to the Ministry of Finance, which amount to 343.76 billion yen (up 12.1 %). The budgetary requests by the Science and Technology Agency are 179.24 billion yen in the general account and 90.21 billion yen in the special account for power resource development, and the budgetary requests by the Ministry of International Trade and Industry are 1.03 billion yen and 70.08 billion yen, respectively. The budget demands by the STA, which supervises Power Reactors and Nuclear Fuel Development Corporation, Japan Atomic Energy Research Institute, etc. are for the continuation of current projects, including the beginning of the construction of the prototype FBR Monju and the neutral beam injector for the fusion device JT-60. The budget demands by MITI are similarly for the safety measures and verification tests for nuclear power generation. (Mori, K.)

Rrp12 and the Exportin Crm1 participate in late assembly events in the nucleolus during 40S ribosomal subunit biogenesis.

Science.gov (United States)

Moriggi, Giulia; Nieto, Blanca; Dosil, Mercedes

2014-12-01

During the biogenesis of small ribosomal subunits in eukaryotes, the pre-40S particles formed in the nucleolus are rapidly transported to the cytoplasm. The mechanisms underlying the nuclear export of these particles and its coordination with other biogenesis steps are mostly unknown. Here we show that yeast Rrp12 is required for the exit of pre-40S particles to the cytoplasm and for proper maturation dynamics of upstream 90S pre-ribosomes. Due to this, in vivo elimination of Rrp12 leads to an accumulation of nucleoplasmic 90S to pre-40S transitional particles, abnormal 35S pre-rRNA processing, delayed elimination of processing byproducts, and no export of intermediate pre-40S complexes. The exportin Crm1 is also required for the same pre-ribosome maturation events that involve Rrp12. Thus, in addition to their implication in nuclear export, Rrp12 and Crm1 participate in earlier biosynthetic steps that take place in the nucleolus. Our results indicate that, in the 40S subunit synthesis pathway, the completion of early pre-40S particle assembly, the initiation of byproduct degradation and the priming for nuclear export occur in an integrated manner in late 90S pre-ribosomes.

An analysis of trends and perspectives of U.S.'s nuclear policies

International Nuclear Information System (INIS)

Lee, B. W.; Lee, K. S.; Oh, K. B.

2001-01-01

This paper analyzes the trends and perspectives of U.S.'s nuclear polices. With the changing of the administration of U.S., certain changes in nuclear policies are foreseen under Bush's new administration. Considering the traditional basis of republicans, somewhat positive impacts on nuclear R and D and nuclear power program are expected

Strengthening Canada's nuclear liability regime

International Nuclear Information System (INIS)

McCauley, D.; Henault, J.

2014-01-01

On January 30, 2014, a Bill entitled the Energy Safety and Security Act, was introduced in Parliament that, among other things, would strengthen Canada's nuclear civil liability legislation by replacing the current Nuclear Liability Act. The proposed legislation also includes implementing provisions that would permit Canada to join the International Atomic Energy Agency's Convention on Supplementary Compensation for Nuclear Damage. This paper will discuss the importance of a comprehensive civil liability regime for nuclear damage to a country's legislative framework for nuclear development and will present the key elements of Canada's new legislation and the policy considerations behind them. (author))

U.S.-origin nuclear material removal program

Energy Technology Data Exchange (ETDEWEB)

Messick, C.E.; Galan, J.J. [U.S. Department of Energy, Washington, DC (United States). U.S.-Origin Nuclear Material Removal Program

2014-12-15

The United States (U.S.) Department of Energy (DOE) Global Threat Reduction Initiative's (GTRI) U.S.-Origin Nuclear Material Removal program, also known as the Foreign Research Reactor Spent Nuclear Fuel Acceptance Program (FRR SNF AP), was established by the U.S. Department of Energy in May 1996. The program's mission provides a disposition pathway for certain U.S. origin spent nuclear fuel and other weapons-grade nuclear material. The program will continue until May 2016 with an additional three year window for fuel cooldown and transportation. This paper provides an update on recent program accomplishments, current program initiatives and future activities.

Genetic diversity and population genetic analysis of Donax vittatus (Mollusca: Bivalvia) and phylogeny of the genus with mitochondrial and nuclear markers

Science.gov (United States)

Fernández-Pérez, Jenyfer; Froufe, Elsa; Nantón, Ana; Gaspar, Miguel B.; Méndez, Josefina

2017-10-01

In this study, the genetic diversity of Donax vittatus across the Iberian Peninsula was investigated using four mitochondrial (COI, Cytb, 16S F and M types) and three nuclear (H3, 18S and 28S) genes. These same molecular markers were also sequenced in D. semistriatus and D variegatus to address the phylogenetic relationships of the species of the genus Donax common along the European coasts. Our results showed high haplotype diversity in combination with a low nucleotide diversity and a star-shaped network with a predominant haplotype, indicating a recent population expansion for the examined sampling sites of D. vittatus. Furthermore, analyses of population differentiation performed with COI mitochondrial marker, including global FST estimation and pairwise FST values, indicated the non-existence of significant genetic structure in D. vittatus of Northwest Iberian populations. Because these localities show a high genetic similarity, we suggest that D. vittatus could be a potentially alternative exploitable resource, as complement to the D. trunculus fisheries, whose natural stocks have decreased dramatically in some areas. Furthermore, we present for the first time, evidence of DUI in the clams D. vittatus and D. semistriatus.

Molecular Identification of Paramecium bursaria Syngens and Studies on Geographic Distribution using Mitochondrial Cytochrome C Oxidase Subunit I (COI).

Science.gov (United States)

Zagata, Patrycja; Greczek-Stachura, Magdalena; Tarcz, Sebastian; Rautian, Maria

2015-01-01

Paramecium bursaria is composed of five syngens that are morphologically indistinguishable but sexually isolated. The aim of the present study was to confirm by molecular methods (analyses of mitochondrial COI) the identification of P. bursaria syngens originating from different geographical locations. Phylograms constructed using both the neighbor-joining and maximum-likelihood methods based on a comparison of 34 sequences of P. bursaria strains and P. multimicronucleatum, P. caudatum and P.calkinsi strains used as outgroups revealed five clusters which correspond to results obtained previously by mating reaction. Our analysis shows the existence of 24 haplotypes for the COI gene sequence in the studied strains. The interspecies haplotype diversity was Hd = 0.967. We confirmed genetic differentiation between strains of P. bursaria and the occurrence of a correlation between geographical distribution and the correspondent syngen.

Role of S100A12 in the pathogenesis of osteoarthritis

Energy Technology Data Exchange (ETDEWEB)

Nakashima, Motoshige [Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550 (Japan); Sakai, Tadahiro, E-mail: tadsakai@med.nagoya-u.ac.jp [Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550 (Japan); Hiraiwa, Hideki; Hamada, Takashi; Omachi, Takaaki [Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550 (Japan); Ono, Yohei [Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550 (Japan); Department of Anatomy and Cell Biology, Brody School of Medicine, East Carolina University, 600 Moye Blvd., Greenville, NC 27834 (United States); Inukai, Norio [Department of Orthopaedic Surgery, Nishio Municipal Hospital, 6 Kumami-cho, Nishio 445-8510 (Japan); Ishizuka, Shinya; Matsukawa, Tetsuya; Oda, Tomoyuki; Takamatsu, Akira; Yamashita, Satoshi; Ishiguro, Naoki [Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550 (Japan)

2012-06-08

Highlights: Black-Right-Pointing-Pointer This is the first report of S100A12 expression in human OA articular cartilages. Black-Right-Pointing-Pointer Exogenous S100A12 increased the production of MMP13 and VEGF in OA chondrocytes. Black-Right-Pointing-Pointer Soluble RAGE suppressed the increased production of MMP13 and VEGF. Black-Right-Pointing-Pointer p38MAPK and NF-{kappa}B inhibitors abrogated S100A12-induced MMP13 and VEGF production. Black-Right-Pointing-Pointer S100A12 may contribute to OA progression by increasing MMP13 and VEGF production. -- Abstract: S100A12 is a member of the S100 protein family, which are intracellular calcium-binding proteins. Although there are many reports on the involvement of S100A12 in inflammatory diseases, its presence in osteoarthritic cartilage has not been reported. The purpose of this study was to investigate the expression of S100A12 in human articular cartilage in osteoarthritis (OA) and to evaluate the role of S100A12 in human OA chondrocytes. We analyzed S100A12 expression by immunohistochemical staining of cartilage samples obtained from OA and non-OA patients. In addition, chondrocytes were isolated from knee cartilage of OA patients and treated with recombinant human S100A12. Real-time RT-PCR was performed to analyze mRNA expression. Protein production of matrix metalloproteinase 13 (MMP-13) and vascular endothelial growth factor (VEGF) in the culture medium were measured by ELISA. Immunohistochemical analyses revealed that S100A12 expression was markedly increased in OA cartilages. Protein production and mRNA expression of MMP-13 and VEGF in cultured OA chondrocytes were significantly increased by treatment with exogenous S100A12. These increases in mRNA expression and protein production were suppressed by administration of soluble receptor for advanced glycation end products (RAGE). Both p38 mitogen-activated protein kinase (MAPK) and nuclear factor-{kappa}B (NF-{kappa}B) inhibitors also suppressed the increases

The role of nuclear power in the U.S.A

International Nuclear Information System (INIS)

Walske, Carl.

1981-06-01

Presently the United States has a total electrical generating capacity of about 600 gigawatts, of which 56 GW is nuclear-fuelled. Actual generation is about 12 percent nuclear. Another 90 GW nuclear and 130 GW coal-fired capacity are under construction. No new orders for nuclear power plants have been received since 1978, and recently cancellations for nuclear plants have been exceeding gross coal ordering rates. If U.S. utilities are to continue to expand at their current rate, at least 40 GW of new capacity should be ordered every year. By the year 2000 another 20-70 percent more energy will be needed to meet the demand from a mature population with an increased proportion in the work force. Double-digit inflation, increased regulatory requirements, and higher fuel costs have made it difficult for electric utilites to obtain financing for new plants; time delays in obtaining regulatory agency approvals have added interest expenses to the cost of plants already under construction. The political climate is improving for nuclear power, and public opinion remains generally favourable

U.S. Department of Energy operational experience with shipments of foreign research reactor spent nuclear fuel

International Nuclear Information System (INIS)

Messick, Charles E.; Massey, Charles D.; Mustin, Tracy P.

1998-01-01

On May 13, 1996, the U.S. Department of Energy issued a Record of Decision on a Nuclear Weapons Nonproliferation Policy Concerning Foreign Research Reactor Spent Nuclear Fuel. The goal of the long-term policy is to recover enriched uranium exported from the United States, while giving foreign research reactor operators sufficient time to develop their own long-term solutions for storage and disposal of spent fuel. The spent fuel accepted by the U.S. DOE under the policy must be out of the research reactors by May 12, 2006 and returned to the United States by May 12, 2009. (author)

U.S. nuclear exotica: Peaceful use of nuclear explosives

International Nuclear Information System (INIS)

Sylves, R.T.

1986-01-01

Project Plowshare, the U.S. Atomic Energy Commission (AEC) program to investigate possible non-military uses for nuclear explosives, was an offshoot of President Eisenhower's ''Atoms for Peace'' proposal. Plowshare was, in a sense, two separate programs. One was for nuclear excavation projects applied to grand-scale civil engineering ventures. Much of what had sustained nuclear excavation Plowshare in the 1960s was the hope and belief that this new instrument of civil engineering would prove its value in construction of a second great Pan-American canal. The other was for contained underground blasting to serve parties interested in mining, underground natural gas storage, and long-term disposal of toxic and radioactive materials. Both programs were intertwined with military and national security-related experiments. Given the heavy security which justifiably surrounded AEC use of thermonuclear devices, and fears of nuclear terrorism as well as nuclear proliferation concerns, even Plowshare's most ardent supporters never expected the project to hand private industry a thermonuclear explosive device

Nuclear proliferation: the U.S.-Indian conflict

International Nuclear Information System (INIS)

Chellaney, Brahma.

1993-01-01

The history of the present conflicting positions of U.S. and India on the issue of nuclear proliferation is narrated and various aspects of this U.S. India controversy are studied. These aspects are: U.S.-India cooperation in the nuclear field in the fifties and sixties; India's peaceful nuclear explosion (PNE) in 1974 and U.S. policy of containment through denial of nuclear fuel and spare parts supply for Tarapur Atomic Power Station; and the political, technical and legal aspects of the nuclear conflict between U.S. and India. Since India's PNE in 1974, U.S. has made India a target of its non-proliferation strategy and is coordinating multinational efforts in erecting barriers in the flow of dual-use sensitive technologies to India. The recent instance is U.S. pressure on Russia to cancel the contract with India to sell cryogenic rocket engine technology required for India's civilian space programme. Even though apparently the conflict is over nuclear proliferation issue, in essence it is a conflict between U.S. determination to restrict high-technology transfer to India on one hand and India's resolve to maintain its nuclear independence on the other hand. The study is based on primary sources in the form of U.S. and Indian government documents. Texts of important government documents are given in appendices and bibliographies of primary and secondary sources used in the study are included. (M.G.B.)

U.S.-origin nuclear material removal program

International Nuclear Information System (INIS)

Messick, C.E.; Galan, J.J.

2014-01-01

The United States (U.S.) Department of Energy (DOE) Global Threat Reduction Initiative's (GTRI) U.S.-Origin Nuclear Material Removal program, also known as the Foreign Research Reactor Spent Nuclear Fuel Acceptance Program (FRR SNF AP), was established by the U.S. Department of Energy in May 1996. The program's mission provides a disposition pathway for certain U.S. origin spent nuclear fuel and other weapons-grade nuclear material. The program will continue until May 2016 with an additional three year window for fuel cooldown and transportation. This paper provides an update on recent program accomplishments, current program initiatives and future activities.

Comparative performance of the 16S rRNA gene in DNA barcoding of amphibians

Directory of Open Access Journals (Sweden)

Chiari Ylenia

2005-03-01

Full Text Available Abstract Background Identifying species of organisms by short sequences of DNA has been in the center of ongoing discussions under the terms DNA barcoding or DNA taxonomy. A C-terminal fragment of the mitochondrial gene for cytochrome oxidase subunit I (COI has been proposed as universal marker for this purpose among animals. Results Herein we present experimental evidence that the mitochondrial 16S rRNA gene fulfills the requirements for a universal DNA barcoding marker in amphibians. In terms of universality of priming sites and identification of major vertebrate clades the studied 16S fragment is superior to COI. Amplification success was 100% for 16S in a subset of fresh and well-preserved samples of Madagascan frogs, while various combination of COI primers had lower success rates.COI priming sites showed high variability among amphibians both at the level of groups and closely related species, whereas 16S priming sites were highly conserved among vertebrates. Interspecific pairwise 16S divergences in a test group of Madagascan frogs were at a level suitable for assignment of larval stages to species (1–17%, with low degrees of pairwise haplotype divergence within populations (0–1%. Conclusion We strongly advocate the use of 16S rRNA as standard DNA barcoding marker for vertebrates to complement COI, especially if samples a priori could belong to various phylogenetically distant taxa and false negatives would constitute a major problem.

PI3K-Akt-mTORC1-S6K1/2 Axis Controls Th17 Differentiation by Regulating Gfi1 Expression and Nuclear Translocation of RORγ

Directory of Open Access Journals (Sweden)

Yutaka Kurebayashi

2012-04-01

Full Text Available The PI3K-Akt-mTORC1 axis contributes to the activation, survival, and proliferation of CD4+ T cells upon stimulation through TCR and CD28. Here, we demonstrate that the suppression of this axis by deletion of p85α or PI3K/mTORC1 inhibitors as well as T cell-specific deletion of raptor, an essential component of mTORC1, impairs Th17 differentiation in vitro and in vivo in a S6K1/2-dependent fashion. Inhibition of PI3K-Akt-mTORC1-S6K1 axis impairs the downregulation of Gfi1, a negative regulator of Th17 differentiation. Furthermore, we demonstrate that S6K2, a nuclear counterpart of S6K1, is induced by the PI3K-Akt-mTORC1 axis, binds RORγ, and carries RORγ to the nucleus. These results point toward a pivotal role of PI3K-Akt-mTORC1-S6K1/2 axis in Th17 differentiation.

PREFACE: 12th Conference on ''Theoretical Nuclear Physics in Italy''

Science.gov (United States)

Bombaci, I.; Covello, A.; Marcucci, L. E.; Rosati, S.

2009-07-01

These Proceedings contain the invited and contributed papers presented at the 12th Conference on Theoretical Nuclear Physics in Italy held in Cortona, Italy, from 8-10 October 2008. As usual, the meeting was held at il Palazzone, a 16th century castle owned by the Scuola Normale Superiore di Pisa. The aim of this biennal conference is to bring together Italian theorists working in various fields of Nuclear Physics to discuss their latest results and confront their points of view in a lively and informal way. This offers the opportunity to promote collaborations between different groups. There were about 50 participants at the conference, coming from 14 Italian Universities (Cagliari, Catania, Ferrara, Firenze, Genova, Lecce, Milano, Napoli, Padova, Pavia, Pisa, Roma, Trento, Trieste). The program of the conference, prepared by the Organizing Committee (Ignazio Bombaci, Aldo Covello, Laura Elisa Marcucci and Sergio Rosati) focused on six main topics: Few-Nucleon Systems, Nuclear Matter and Nuclear Dynamics, Nuclear Astrophysics, Structure of Hadrons and Hadronic Matter, Nuclear Structure, Nuclear Physics with Electroweak Probes. Winfried Leidemann, Maria Colonna, Marcello Lissia, Elena Santopinto, Silvia Lenzi and Omar Benhar took the burden of giving general talks on these topics and reviewing the research activities of the various Italian groups. In addition, 19 contributed papers were presented, most of them by young participants. In the last session of the Conference there were two invited talks related to experimental activities of great current interest. Gianfranco Prete from the Laboratori Nazionali di Legnaro spoke about the Italian radioactive ion beam facility SPES and the status of the European project EURISOL, while Nicola Colonna from the INFN, Bari, gave an overview of the perspectives of development of fourth-generation nuclear reactors. We would like to thank the authors of the general reports for their hard work in reviewing the main achievements in

Genetic variation of the greenhouse whitefly, Trialeurodes vaporariorum (Hemiptera: Aleyrodidae), among populations from Serbia and neighbouring countries, as inferred from COI sequence variability.

Science.gov (United States)

Prijović, M; Skaljac, M; Drobnjaković, T; Zanić, K; Perić, P; Marčić, D; Puizina, J

2014-06-01

The greenhouse whitefly Trialeurodes vaporariorum Westwood, 1856 (Hemiptera: Aleyrodidae) is an invasive and highly polyphagous phloem-feeding pest of vegetables and ornamentals. Trialeurodes vaporariorum causes serious damage due to direct feeding and transmits several important plant viruses. Excessive use of insecticides has resulted in significantly reduced levels of susceptibility of various T. vaporariorum populations. To determine the genetic variability within and among populations of T. vaporariorum from Serbia and to explore their genetic relatedness with other T. vaporariorum populations, we analysed the mitochondrial cytochrome c oxidase I (COI) sequences of 16 populations from Serbia and six neighbouring countries: Montenegro (three populations), Macedonia (one population) and Croatia (two populations), for a total of 198 analysed specimens. A low overall level of sequence divergence and only five variable nucleotides and six haplotypes were found. The most frequent haplotype, H1, was identified in all Serbian populations and in all specimens from distant localities in Croatia and Macedonia. The COI sequence data that was retrieved from GenBank and the data from our study indicated that H1 is the most globally widespread T. vaporariorum haplotype. A lack of spatial genetic structure among the studied T. vaporariorum populations, as well as two demographic tests that we performed (Tajima's D value and Fu's Fs statistics), indicate a recent colonisation event and population growth. Phylogenetic analyses of the COI haplotypes in this study and other T. vaporariorum haplotypes that were retrieved from GenBank were performed using Bayesian inference and median-joining (MJ) network analysis. Two major haplogroups with only a single unique nucleotide difference were found: haplogroup 1 (containing the five Serbian haplotypes and those previously identified in India, China, the Netherlands, the United Kingdom, Morocco, Reunion and the USA) and haplogroup 3

North Korea’s Nuclear Weapons Development and Diplomacy

Science.gov (United States)

2007-01-03

December 23, 2006. P. A12. Many of Kim Jong-il’s luxury goods purchases have been in Europe. They include Mercedes Benz and BMW automobiles, expensive...small scale atomic bomb. Most believed that North Korea had not reached the technology level to test the prototype of a small nuclear warhead.1 The...and possibly other weapons technology to Iran. There are known divisions within the Chinese government and Communist Party over the issue of support

Nuclear future: thinking for building. Proceedings of the 5. Brazilian national meeting on nuclear applications; 8. General congress on nuclear energy; 12. Brazilian national meeting on reactor physics and thermal hydraulics; Futuro nuclear: refletindo para construir. Anais do 5. Encontro nacional de aplicacoes nucleares; 8. Congresso geral de energia nuclear; 12. Encontro nacional de fisica de reatores e termo-hidraulica

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-07-01

These proceedings, for the first time, present jointly the 12. Brazilian national meeting on reactor physics and thermal hydraulics (12. ENFIR), the 8. General congress on nuclear energy (8. CGEN), and the 5. Brazilian national meeting on nuclear applications (5. ENAN). The main theme of discussion was: 'Nuclear Future: thinking for building'. The papers have analysed the progresses of peaceful utilization of nuclear technology and its forecasting for the beginning of the new millennium. The construction of Angra-3 nuclear power plant have been discussed.

Nuclear future: thinking for building. Proceedings of the 12. Brazilian national meeting on reactor physics and thermal hydraulics; 8. General congress on nuclear energy; 5. Brazilian national meeting on nuclear applications; Futuro nuclear: refletindo para construir. Anais do 12. Encontro nacional de fisica de reatores e termo-hidraulica; 8. Congresso geral de energia nuclear; 5. Encontro nacional de aplicacoes nucleares

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-07-01

These proceedings, for the first time, present jointly the 12. Brazilian national meeting on reactor physics and thermal hydraulics (12 ENFIR), 8. General congress on nuclear energy (8. CGEN), and 5. Brazilian national meeting on nuclear applications (5. ENAN). The main theme of discussion was: 'Nuclear Future: thinking for building'. The papers have analysed the progresses of peaceful utilization of nuclear technology and its forecasting for the beginning of the new millennium. The construction of Angra-3 nuclear power plant have been discussed.

U.S. Nuclear Power Reactor Plant Status

Data.gov (United States)

Nuclear Regulatory Commission — Demographic data on U.S. commercial nuclear power reactors, including: plant name/unit number, docket number, location, licensee, reactor/containment type, nuclear...

Phylogenetic relationships of the Gomphales based on nuc-25S-rDNA, mit-12S-rDNA, and mit-atp6-DNA combined sequences

Science.gov (United States)

Admir J. Giachini; Kentaro Hosaka; Eduardo Nouhra; Joseph Spatafora; James M. Trappe

2010-01-01

Phylogenetic relationships among Geastrales, Gomphales, Hysterangiales, and Phallales were estimated via combined sequences: nuclear large subunit ribosomal DNA (nuc-25S-rDNA), mitochondrial small subunit ribosomal DNA (mit-12S-rDNA), and mitochondrial atp6 DNA (mit-atp6-DNA). Eighty-one taxa comprising 19 genera and 58 species...

The Nuclear Science Facility at San Jose State University and the U.S. Department of Energy sponsored Summer School in Nuclear Chemistry

International Nuclear Information System (INIS)

Ling, A.C.

1990-01-01

The Nuclear Science Facility at SJSU was first opened for classes in 1975. It is designed primarily for undergraduate teaching of nuclear chemistry, radiochemistry, tracer techniques, and radiation safety. Utilizing nearly $1.5 million in counting equipment alone, but excluding a reactor or accelerator, it allows simultaneous use of multiple counting assemblages for up to 20 individual students, even for advanced experiments with Ge/MCA units. Current academic programs include a B.S. Degree in Radiochemistry, an M.S. in Radiological Health Physics, and community outreach to grade schools (nearly 2,000 student-experiments for grades 7-12 were performed in AY88/89). To encourage nuclear chemistry as a potential area of study in graduate school, the US Department of Energy funded a special national Summer School in Nuclear Chemistry. This was first held at SJSU in 1984; summer 1990 will see the seventh such program taught

Review of 12-hour shifts at nuclear generating stations

International Nuclear Information System (INIS)

Smiley, A.; Moray, N.P.

1989-04-01

This project reviewed the practice of 12-hour shift work schedules at nuclear power plants, and its relationship to safety. The current literature was examined for information on accidents, fatigue and personal preferences. Interviews with operators and maintainers showed that these groups had attitude and preference differences related to both 12 hour shift schedules and overtime work opportunities. Several factors related to 12-hour schedules were identified which could affect safety, but which have not been adequately considered. (24 refs.)

Industry perspectives on the U.S. used nuclear fuel management program

International Nuclear Information System (INIS)

Matzie, R.

2001-01-01

The U.S. used nuclear fuel management program is at a critical juncture. It has been 17 years since the U.S. Congress authorized geologic disposal of used nuclear fuel and 12 years since Congress elected to study Yucca Mountain, Nevada, as the nation's lone long-term disposal option. During this period, Yucca Mountain's ability to isolate long-lived radionuclides was the subject of considerable scientific study. Concurrently, specialists expended significant design effort on the engineered barriers that work in conjunction with the proposed repository's natural features to ensure that health protection standards are met. Confidence as to the soundness of the geologic disposal option is high. While technical progress on geologic disposal is substantial, policy level decision-making needed to move the program forward remains lacking. A number of important policy questions concerning used fuel management remain unanswered as this fuel accumulates at 103 operating U.S. commercial nuclear power reactors at 65 sites. Wet fuel storage space at those locations is becoming increasingly scarce. This paper will review both the scientific successes and policy challenges on the road to geologic disposal. It will outline the nation's used nuclear fuel storage needs, highlight what the nation's scientists have learned about geologic disposal, discuss what is being done to meet near-term interim storage requirements, describe the emerging regulatory framework associated with the program and summarize the ongoing policy debate. (author)

Entrapped by the uneven central and Middle Eastern terrains: Genetic status of populations of Hirudo orientalis (Annelida, Clitellata, Hirudinida) with a phylogenetic review of the genus Hirudo.

Science.gov (United States)

Darabi-Darestani, Kaveh; Sari, Alireza; Sarafrazi, Alimorad; Utevsky, Serge

2018-04-01

Phylogenetic relationships between species of the genus Hirudo plus genetic variation in the entire distribution range of Hirudo orientalis were investigated based on mitochondrial (COI and 12S rDNA) and nuclear (ITS1+5.8S+ITS2) genome regions. The sister relationship of Hirudo orientalis and H. medicinalis was revealed with a high posterior probability. A broad and patchy distribution with minor genetic differences was observed in populations of H. orientalis along the central and Middle Eastern parts of Asia. The known distribution range occurred in topographically heterogeneous landscapes around the Caspian Sea. The demographic analysis suggests the selection of the COI locus under unfavourable respiratory conditions, but population size expansion cannot be fully rejected. The genetic variation trend indicated northward dispersal. Higher haplotype diversity in the South Caspian region potentially suggests the area as a historical refugium for the species. The vast dispersal is assumed to occur after the Pleistocene glaciations via vertebrate hosts. Copyright © 2017 Elsevier Inc. All rights reserved.

Towards A Better U.S. Nuclear Strategy

Directory of Open Access Journals (Sweden)

John J. Klein

2014-10-01

Full Text Available The U.S. nuclear posture and the future role of nuclear deterrence is a topic that continues to be hotly debated. This situation will continue because of changes in the international security environment and the pressure to find reductions within the U.S. defense budget. Regardless of claims to the contrary, nuclear deterrence remains critical in ensuring future peace and stability.

Coherent fragmentation of 12C nuclei of momentum 4.5 GeV/ c per nucleon through the 8Beg.s.+4He channel in a nuclear photoemulsion containing lead nuclei

Science.gov (United States)

Belaga, V. V.; Gerasimov, S. G.; Dronov, V. A.; Peresadko, N. G.; Pisetskaya, A. V.; Rusakova, V. V.; Fetisov, V. N.; Kharlamov, S. P.; Shesterkina, L. N.

2017-07-01

A two-particle channel in which an unbound nucleus of 8Be in the ground state (8Beg.s.) was one of the fragments was selected among events where 12C nuclei of momentum 4.5 GeV/c per nucleon undergo coherent dissociation into three alpha particles. The events in question were detected in a track nuclear photoemulsion containing lead nuclei, which was irradiated at the synchrophasotron of the Laboratory of High Energies at the Joint Institute for Nuclear Research (JINR, Dubna). The average transverse momentum of alpha particles produced upon the decay of 8Beg.s. nuclei was 87±6 MeV/ c, while that for "single" alpha (αs) particles was 123±15 MeV/ c. The average value of the transverse-momentum transfer in the reaction being considered, Pt(12C), was 223 ± 20 MeV/ c. The average value of the cross section for this channel involving Ag and Br target nuclei was 13 ± 4 mb, while the cross section for the reaction on the Pb nucleus was 40 ± 15 mb. The Coulomb dissociation contribution evaluated on the basis of the number of events where the momentum P t(12C) did not exceed 0.1 GeV/c saturated about 20%. In nine events, the measured total transverse energy of the fragments in the reference frame comoving with the decaying carbon nucleus did not exceed 0.45 MeV, which did not contradict the excitation of the participant 12C nucleus to the level at 7.65 MeV. The average value of the transverse momentum in those events was 234 ± 25 MeV/ c.

Maternal mismatches in farmed tilapia strains (Oreochromis spp.) in the Philippines as revealed by mitochondrial COI gene.

Science.gov (United States)

Ordoñez, June Feliciano F; Ventolero, Minerva Fatimae H; Santos, Mudjekeewis D

2017-07-01

The introduction of genetically enhanced tilapia has significantly boosted the performance of Philippine aquaculture industry. While enhanced strains contribute to the increase in tilapia production, genetic characterization of present tilapia stocks is critical to maintain their quality and to ensure the genetic gains are sustained. To understand and determine the genetic relationship of the genetically enhanced strains produced in the Philippines, mitochondrial cytochrome oxidase subunit I (COI) gene using DNA barcoding approach was analyzed. Specimens representing 10 genetically enhanced strains (GIFT, FaST, GET-EXCEL, GST, SST, COLD, YY-male, GMT, Molobicus, and BEST), three red tilapia (Taiwan red, Florida red, and FAC-red), and two pure lines (initially identified as O. aureus and O. spilurus) were collected, sequenced, and identified using DNA barcoding. Results revealed that farmed tilapias consisted of four different Oreochromis species. As expected, COI could not distinguish individuals at the strain level but surprisingly, mismatch between the species of maternal origin and present-day offspring was observed. This particular result may pose a question on the genetic purity and integrity of the strains being distributed to farmers and suggests a re-evaluation of the effectiveness of major tilapia breeding centers in maintaining their stocks.

New or little-known species of Chaetocladius s. str. Kieffer, 1911 (Diptera: Chironomidae: Orthocladiinae) from the Amur River basin (Russian Far East).

Science.gov (United States)

Makarchenko, Eugenyi A; Makarchenko, Marina A; Semenchenko, Alexander A

2017-03-27

Chironomids of the subgenus Chaetocladius s. str. from the Amur River basin are revised using both morphological characters and molecular data. Three new species, C. egorych sp. nov., C. lopatinskiy sp. nov. and C. yavorskayae sp. nov., are described and figured. The pupa of C. fedotkin is described for the first time. Adult males of C. ligni and C. piger, little-known in the Far East, are redescribed and annotated, and key to males of the Chaetocladius s. str. from the Amur River basin is provided. A reference 658 bp barcode sequence from a fragment of the mitochondrial gene cytochrome oxidase I (COI) was used as a tool for species delimitation. Comparisons with corresponding regions of COI between 5 species in the subgenus produced K2P genetic distances of 8.3-12.6%, values well associated with interspecific variation. Molecular data were also used for the reconstruction of the phylogenetic relationships within the subgenus Chaetocladius s. str.

Nuclear polarization in hydrogenlike 82208Pb81+

International Nuclear Information System (INIS)

Haga, Akihiro; Tanaka, Yasutoshi; Horikawa, Yataro

2002-01-01

We calculate nuclear-polarization energy shifts for the hydrogenlike 82 208 Pb 81+ . The retarded transverse part as well as the longitudinal part is taken into account as the electromagnetic interaction between an electron and the nucleus. With a finite charge distribution for the nuclear ground state and the random-phase approximation to describe the nuclear excitations, we obtain nuclear-polarization energy of the 1s 1/2 state as -38.2 (-37.0) meV in the Feynman (Coulomb) gauge. For the 2s 1/2 , 2p 1/2 , and 2p 3/2 states, they are -6.7 (-6.4), -0.2 (-0.2), and +0.0 (+0.0) meV, respectively. The transverse contribution is small in comparison with the longitudinal nuclear-polarization correction. It is about 12% both for the 1s 1/2 and 2s 1/2 states. The seagull term in the two-photon exchange diagrams is also shown to be quite important to obtain the gauge-invariant nuclear-polarization energies

NUCLEAR NONPROLIFERATION: U.S. Efforts to Combat Nuclear Smuggling

National Research Council Canada - National Science Library

2002-01-01

...) information about efforts to combat nuclear smuggling at U.S. borders. My statement today is based on the results of our May 16, 2002, report on this subject1 and information we obtained from the U.S...

International Nuclear Management Academy Requirements for University Master’s Programmes in Nuclear Technology Management

International Nuclear Information System (INIS)

Grosbois, J. de; Hirose, H.; Adachi, F.; Liu, L.; Hanamitsu, K.; Kosilov, A.; Roberts, J.

2016-01-01

Full text: The development of any national nuclear energy programme is dependent on the successful development of qualified human resources, through a sustainable nuclear education and training programmes supported by government and industry. Among the broad range of specialists needed for the continued safe and economic utilization of nuclear technology for peaceful purposes, are a most vital component—managers. The International Nuclear Management Academy (INMA) is an IAEA facilitated collaboration framework in which universities provide master’s degree programmes focusing on the management aspect for the nuclear sector. INMA master’s programmes in Nuclear Technology Management (NTM) specify a common set of competency requirements that graduates should acquire to prepare them to become competent managers. This paper presents an overview of the INMA collaboration framework and the requirements for partner universities to implement master’s programmes in Nuclear Technology Management. (author

10 CFR 30.12 - Persons using byproduct material under certain Department of Energy and Nuclear Regulatory...

Science.gov (United States)

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Persons using byproduct material under certain Department of Energy and Nuclear Regulatory Commission contracts. 30.12 Section 30.12 Energy NUCLEAR REGULATORY... Persons using byproduct material under certain Department of Energy and Nuclear Regulatory Commission...

Women’s Participation in Africa’s Nuclear Development-Challenges and Opportunities

International Nuclear Information System (INIS)

Mkhosi-Motsaathebe, M.

2015-01-01

Expansion of nuclear technologies and plans for new plants in Africa makes this an exciting time for more women to be involved in the nuclear sector and there are lots of opportunities across the nuclear value chain for women to be involved. In recent decades, more and more women are are now entering the nuclear field and many people are starting to recognise opportunities for women, since the role played by women in the nuclear field enhances the development goals for many countries. In developing countries and in Africa in particular, however, there is a greater need for awareness of women’s involvement in STEM fields in general, and to change prevailing attitudes about women’s participation in the nuclear science and technology in particular. This paper will look at various opportunities women have in the expanding nuclear sector in the continent, and how these opportunities can be utilised, not only for those in sciences but also in business disciplines. The approaches organizations and countries can take in broadening participation of the female gender in the nuclear development in Africa; will also be presented, as well as how to address the challenges faced by women in the dynamic nuclear field. (author)

South Africa's Nuclear Skills Development Initiatives

Energy Technology Data Exchange (ETDEWEB)

Matube, Ntebatse [NECSA, P.O. BOX 582, 00001 Pretoria (South Africa)

2008-07-01

South Africa's long nuclear history has enabled it to develop and explore new nuclear technologies. The country's nuclear industry is becoming innovative and will soon be able to compete within the global nuclear market. This includes projects such as the Pebble-Bed Modular Reactor (PBMR), a generation IV reactor technology, whose construction is anticipated by 2009. This will put South Africa in the fore-front of new technologies. Globally, the nuclear sector is experiencing a renaissance with political support from most governments. The South African government intends to expand the nuclear component in the energy supply mix of the country as a result of an energy crisis resulting from economic growth and thus high demand which will soon outstrip supply. This increased energy demand requires the country to take measures to counteract the crisis. It has been projected that an additional 40000 Megawatts of electricity will be required over the next 20 years in South Africa. Currently about 90% of South Africa's electricity is generated from coal and about 6% from nuclear. The South African electricity utility, Eskom is investigating the expansion of the utility's nuclear power capacity. These investigations are aimed at a potential increase of nuclear capacity to 20000 Megawatts by 2025. Eskom is in the initial phase of the investigation and is considering advanced Pressurized Water Reactors (PWRs) with a combined capacity of around 3500 Megawatts. This planned expansion of the nuclear energy generating program has presented a challenge of developing and maintaining skills and competencies required by the program. The South African government has acknowledged that they do have a challenge and are going to have to develop an aggressive approach to acquire the necessary skills and competencies required for the program. This aggressive approach will have to accelerate the development of nuclear human capital capacity by ensuring that we utilize the

Department of Energy: Nuclear S&T workforce development programs

International Nuclear Information System (INIS)

Bingham, Michelle; Bala, Marsha; Beierschmitt, Kelly; Steele, Carolyn; Sattelberger, Alfred P.; Bruozas, Meridith A.

2016-01-01

The U.S. Department of Energy (DOE) national laboratories use their expertise in nuclear science and technology (S&T) to support a robust national nuclear S&T enterprise from the ground up. Traditional academic programs do not provide all the elements necessary to develop this expertise, so the DOE has initiated a number of supplemental programs to develop and support the nuclear S&T workforce pipeline. This document catalogs existing workforce development programs that are supported by a number of DOE offices (such as the Offices of Nuclear Energy, Science, Energy Efficiency, and Environmental Management), and by the National Nuclear Security Administration (NNSA) and the Naval Reactor Program. Workforce development programs in nuclear S&T administered through the Department of Homeland Security, the Nuclear Regulatory Commission, and the Department of Defense are also included. The information about these programs, which is cataloged below, is drawn from the program websites. Some programs, such as the Minority Serving Institutes Partnership Programs (MSIPPs) are available through more than one DOE office, so they appear in more than one section of this document.

Evidence of a Native Northwest Atlantic COI Haplotype Clade in the Cryptogenic Colonial Ascidian Botryllus schlosseri.

Science.gov (United States)

Yund, Philip O; Collins, Catherine; Johnson, Sheri L

2015-06-01

The colonial ascidian Botryllus schlosseri should be considered cryptogenic (i.e., not definitively classified as either native or introduced) in the Northwest Atlantic. Although all the evidence is quite circumstantial, over the last 15 years most research groups have accepted the scenario of human-mediated dispersal and classified B. schlosseri as introduced; others have continued to consider it native or cryptogenic. We address the invasion status of this species by adding 174 sequences to the growing worldwide database for the mitochondrial gene cytochrome c oxidase subunit I (COI) and analyzing 1077 sequences to compare genetic diversity of one clade of haplotypes in the Northwest Atlantic with two hypothesized source regions (the Northeast Atlantic and Mediterranean). Our results lead us to reject the prevailing view of the directionality of transport across the Atlantic. We argue that the genetic diversity patterns at COI are far more consistent with the existence of at least one haplotype clade in the Northwest Atlantic (and possibly a second) that substantially pre-dates human colonization from Europe, with this native North American clade subsequently introduced to three sites in Northeast Atlantic and Mediterranean waters. However, we agree with past researchers that some sites in the Northwest Atlantic have more recently been invaded by alien haplotypes, so that some populations are currently composed of a mixture of native and invader haplotypes. © 2015 Marine Biological Laboratory.

Nuclear molecules in the systems 12C+12C and 16O+16O

International Nuclear Information System (INIS)

Tiereth, W.

1986-01-01

For the two heavy ion systems 12 C+ 12 C and 16 O+ 16 O by means of scattering experiments studies on the phenomena of nuclear molecules were performed. For the 12 C+ 12 C system in the range of the Coulomb wall precision measurements of the elastic scattering were performed. In the two energy ranges of 5.5 ≤ E c.m. ≤ 6.65 MeV and 6.95 ≤ E c.m ≤ 7.375 MeV where the existence of many quasimolecular resonances is known in energy steps of ΔE c.m. = 25 keV angular distributions in the range 10 0 ≤ θ c.m. ≤ 90 0 with Δθ c.m. = 1 0 were measured. For several of the found quasimolecular resonances the spin and the carbon width could be uniquely determined. This was reached by a partial wave analysis of the obtained data. Supplemented were the measurements of the elastic scattering by measurements of the excitation function of the θ 0 exit channel of the reaction 12 ( 12 C, θ) 20 Ne in the energy range from 5.2 ≤ E c.m. ≤ 6.1 MeV. At some known resonances in the 16 O+ 16 O system in the energy range from 15.5 MeV to 18 MeV the spin and the elastic width of these structures could be determined. For this a constrained partial wave analysis on complete angular distributions of the elastic scattering (9 0 ≤ θ c.m. ≤ 90 0 ) which were measured in energy steps of ΔE c.m. = 50 keV was performed. In the 16 O+ 16 O system besides the proof for the existence of a nuclear glory scattering was given. (orig.) [de

UAE’s Experience with Nuclear Knowledge Management

International Nuclear Information System (INIS)

Alkaabi, H.

2016-01-01

Full text: United Arab Emirates (UAE) has embarked upon a nuclear energy programme as part of the nation’s strategy to meet its growing energy demands. At that time, UAE had experience in using radiation-related technologies for medical and industrial purposes, but relatively few citizens were trained in the technologies and management skills needed for an advanced nuclear power sector. Much effort went into developing relevant strategies and procedures to ensure the success and long-term sustainability of the national program. UAE has committed to an extensive human capacity development and nuclear knowledge management programmes to provide Emiratis with the required nuclear training. Main national nuclear stakeholders in collaboration with domestic and international academic institutions are implementing the national strategy for human resources development. UAE contracted with the Korean suppliers to construct the Barakah nuclear power plant with four advanced nuclear reactors currently under advanced stage of construction, rapidly bringing extensive foreign experience into the country. Today, national nuclear stakeholders have vigorous knowledge management projects designed to maintain and develop capabilities, and to pass on the international experience to a new generation of skilled Emiratis. This paper describes the progress of the UAE’s “integrated approach” and outlines future development in the area of nuclear knowledge management. (author

Nuclear future: thinking for building. Proceedings of the 12. Brazilian national meeting on reactor physics and thermal hydraulics; 8. General congress on nuclear energy; 5. Brazilian national meeting on nuclear applications

International Nuclear Information System (INIS)

2000-01-01

These proceedings, for the first time, present jointly the 12. Brazilian national meeting on reactor physics and thermal hydraulics (12 ENFIR), 8. General congress on nuclear energy (8. CGEN), and 5. Brazilian national meeting on nuclear applications (5. ENAN). The main theme of discussion was: 'Nuclear Future: thinking for building'. The papers have analysed the progresses of peaceful utilization of nuclear technology and its forecasting for the beginning of the new millennium. The construction of Angra-3 nuclear power plant have been discussed

Molecular evolution of the mitochondrial 12S rRNA in Ungulata (mammalia).

Science.gov (United States)

Douzery, E; Catzeflis, F M

1995-11-01

The complete 12S rRNA gene has been sequenced in 4 Ungulata (hoofed eutherians) and 1 marsupial and compared to 38 available mammalian sequences in order to investigate the molecular evolution of the mitochondrial small-subunit ribosomal RNA molecule. Ungulata were represented by one artiodactyl (the collared peccary, Tayassu tajacu, suborder Suiformes), two perissodactyls (the Grevy's zebra, Equus grevyi, suborder Hippomorpha; the white rhinoceros, Ceratotherium simum, suborder Ceratomorpha), and one hyracoid (the tree hyrax, Dendrohyrax dorsalis). The fifth species was a marsupial, the eastern gray kangaroo (Macropus giganteus). Several transition/transversion biases characterized the pattern of changes between mammalian 12S rRNA molecules. A bias toward transitions was found among 12S rRNA sequences of Ungulata, illustrating the general bias exhibited by ribosomal and protein-encoding genes of the mitochondrial genome. The derivation of a mammalian 12S rRNA secondary structure model from the comparison of 43 eutherian and marsupial sequences evidenced a pronounced bias against transversions in stems. Moreover, transversional compensatory changes were rare events within double-stranded regions of the ribosomal RNA. Evolutionary characteristics of the 12S rRNA were compared with those of the nuclear 18S and 28S rRNAs. From a phylogenetic point of view, transitions, transversions and indels in stems as well as transversional and indels events in loops gave congruent results for comparisons within orders. Some compensatory changes in double-stranded regions and some indels in single-stranded regions also constituted diagnostic events. The 12S rRNA molecule confirmed the monophyly of infraorder Pecora and order Cetacea and demonstrated the monophyly of the suborder Ruminantia was not supported and the branching pattern between Cetacea and the artiodacytyl suborders Ruminantia and Suiformes was not established. The monophyly of the order Perissodactyla was evidenced

Support for the American Chemical Society's Summer Schools in Nuclear and Radiochemistry

Energy Technology Data Exchange (ETDEWEB)

Mantica, Paul F. [Michigan State University

2013-06-20

The ACS Summer Schools in Nuclear and Radiochemistry were held at San Jose State University (SJSU) and Brookhaven National Laboratory (BNL). The Summer Schools offer undergraduate students with U.S. citizenship an opportunity to complete coursework through ACS accredited chemistry degree programs at SJSU or the State University of New York at Stony Brook (SBU). The courses include lecture and laboratory work on the fundamentals and applications of nuclear and radiochemistry. The number of students participating at each site is limited to 12, and the low student-to-instructor ratio is needed due to the intense nature of the six-week program. To broaden the students’ perspectives on nuclear science, prominent research scientists active in nuclear and/or radiochemical research participate in a Guest Lecture Series. Symposia emphasizing environmental chemistry, nuclear medicine, and career opportunities are conducted as a part of the program.

Mutational analysis of the mitochondrial 12S rRNA and tRNASer(UCN) genes in Tunisian patients with nonsyndromic hearing loss

International Nuclear Information System (INIS)

Mkaouar-Rebai, Emna; Tlili, Abdelaziz; Masmoudi, Saber; Louhichi, Nacim; Charfeddine, Ilhem; Amor, Mohamed Ben; Lahmar, Imed; Driss, Nabil; Drira, Mohamed; Ayadi, Hammadi; Fakhfakh, Faiza

2006-01-01

We explored the mitochondrial 12S rRNA and the tRNA Ser(UCN) genes in 100 Tunisian families affected with NSHL and in 100 control individuals. We identified the mitochondrial A1555G mutation in one out of these 100 families and not in the 100 control individuals. Members of this family harbouring the A1555G mutation showed phenotypic heterogeneity which could be explained by an eventual nuclear-mitochondrial interaction. So, we have screened three nuclear genes: GJB2, GJB3, and GJB6 but we have not found correlation between the phenotypic heterogeneity and variants detected in these genes. We explored also the entire mitochondrial 12S rRNA and the tRNA Ser(UCN) genes. We detected five novel polymorphisms: T742C, T794A, A813G, C868T, and C954T, and 12 known polymorphisms in the mitochondrial 12S rRNA gene. None of the 100 families or the 100 controls were found to carry mutations in the tRNA Ser(UCN) gene. We report here First mutational screening of the mitochondrial 12S rRNA and the tRNA Ser(UCN) genes in the Tunisian population which describes the second family harbouring the A1555G mutation in Africa and reveals novel polymorphisms in the mitochondrial 12S rRNA gene

International Nuclear Security Situation And China’s Approach

Institute of Scientific and Technical Information of China (English)

Liu Chong

2016-01-01

Since 2010,the three Nuclear Security Summits have made a number of achievements,but the international nuclear security situation is still not relaxed.The rapid development of China’s domestic nuclear facilities and a large amount of nuclear and radioactive materials related to nuclear power,active international nuclear black market in China’s surrounding regions,rather serious domestic and international terrorist threats as well as the emerging technology development bring about new challenges to nuclear security.Facing the complicated and long-term nuclear security situation,China from the perspective of monitoring mechanism,laws and regulations system,technical capability-building and nuclear emergency preparedness,takes a series of effective measures to build the national nuclear security capacity,and strictly fulfills its international obligations,actively participates in upgrading the international nuclear non-proliferation regime and relevant international rules,and actively takes part in the Nuclear Security Summit process,strengthens bilateral cooperation on nuclear security with major countries especially the United States of America,and jointly organizes various training with International Atomic Energy Agency,which has made great contributions to upgrading the global nuclear security level.At the end of the Nuclear Security Summit process,China should continue to strengthen its domestic nuclear security capacity building,and promote the international community to treat the root causes and symptoms,adopt a comprehensive strategy,and work together,effectively prevent and dissolve the nuclear terrorist threats.

Nuclear future: thinking for building. Proceedings of the 5. Brazilian national meeting on nuclear applications; 8. General congress on nuclear energy; 12. Brazilian national meeting on reactor physics and thermal hydraulics

International Nuclear Information System (INIS)

2000-01-01

These proceedings, for the first time, present jointly the 12. Brazilian national meeting on reactor physics and thermal hydraulics (12. ENFIR), the 8. General congress on nuclear energy (8. CGEN), and the 5. Brazilian national meeting on nuclear applications (5. ENAN). The main theme of discussion was: 'Nuclear Future: thinking for building'. The papers have analysed the progresses of peaceful utilization of nuclear technology and its forecasting for the beginning of the new millennium. The construction of Angra-3 nuclear power plant have been discussed

Analysis of the national nuclear policy environment in the 21st century - Analysis of U.S. nuclear policy and directives for Korea-U.S. cooperation -

International Nuclear Information System (INIS)

Lee, Han Myung; Kim, Kyung Pyo; Kim, Jong Sook; Kim, Hyun Joon; Lee, Dong Jin; Lee, Tae Joon; Jung, Hwan Sam

1994-12-01

In this report, U.S. nuclear utilization and development trends were analyzed focused on nuclear policy changes from the 1950s to recent years. Specifically, the nuclear policy of the Clinton administration which is carrying out both internal reorganization and enhancement of international cooperation, was analyzed in detail. Korea-U.S. nuclear cooperation was analyzed focused on international joint research contracted through national long-term nuclear R and D implementation. In addition, the history of Korea-U.S. JSCNOET(Joint Standing Committee on Nuclear and Other Energy Technology) was analyzed in order to aid decision making on future cooperation between the two countries. 9 figs, 42 tabs, 64 refs. (Author)

Analysis of the national nuclear policy environment in the 21st century - Analysis of U.S. nuclear policy and directives for Korea-U.S. cooperation -

Energy Technology Data Exchange (ETDEWEB)

Lee, Han Myung; Kim, Kyung Pyo; Kim, Jong Sook; Kim, Hyun Joon; Lee, Dong Jin; Lee, Tae Joon; Jung, Hwan Sam [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1994-12-01

In this report, U.S. nuclear utilization and development trends were analyzed focused on nuclear policy changes from the 1950s to recent years. Specifically, the nuclear policy of the Clinton administration which is carrying out both internal reorganization and enhancement of international cooperation, was analyzed in detail. Korea-U.S. nuclear cooperation was analyzed focused on international joint research contracted through national long-term nuclear R and D implementation. In addition, the history of Korea-U.S. JSCNOET(Joint Standing Committee on Nuclear and Other Energy Technology) was analyzed in order to aid decision making on future cooperation between the two countries. 9 figs, 42 tabs, 64 refs. (Author).

The Impact of Financial Conflict of Interest on Surgical Research: An Observational Study of Published Manuscripts.

Science.gov (United States)

Cherla, Deepa V; Viso, Cristina P; Olavarria, Oscar A; Bernardi, Karla; Holihan, Julie L; Mueck, Krislynn M; Flores-Gonzalez, Juan; Liang, Mike K; Adams, Sasha D

2018-02-09

Substantial discrepancies exist between industry-reported and self-reported conflicts of interest (COI). Although authors with relevant, self-reported financial COI are more likely to write studies favorable to industry sponsors, it is unknown whether undisclosed COI have the same effect. We hypothesized that surgeons who fail to disclose COI are more likely to publish findings that are favorable to industry than surgeons with no COI. PubMed was searched for articles in multiple surgical specialties. Financial COI reported by surgeons and industry were compared. COI were considered to be relevant if they were associated with the product(s) mentioned by an article. Primary outcome was favorability, which was defined as an impression favorable to the product(s) discussed by an article and was determined by 3 independent, blinded clinicians for each article. Primary analysis compared incomplete self-disclosure to no COI. Ordered logistic multivariable regression modeling was used to assess factors associated with favorability. Overall, 337 articles were reviewed. There was a high rate of discordance in the reporting of COI (70.3%). When surgeons failed to disclose COI, their conclusions were significantly more likely to favor industry than surgeons without COI (RR 1.2, 95% CI 1.1-1.4, p relevance, disclosure, or monetary amount) were significantly associated with favorability. Any financial COI (disclosed or undisclosed, relevant or not relevant) significantly influence whether studies report findings favorable to industry. More attention must be paid to improving research design, maximizing transparency in medical research, and insisting that surgeons disclose all COI, regardless of perceived relevance.

Problematic barcoding in flatworms: A case-study on monogeneans and rhabdocoels (Platyhelminthes

Directory of Open Access Journals (Sweden)

Maarten Vanhove

2013-12-01

Full Text Available Some taxonomic groups are less amenable to mitochondrial DNA barcoding than others. Due to the paucity of molecular information of understudied groups and the huge molecular diversity within flatworms, primer design has been hampered. Indeed, all attempts to develop universal flatworm-specific COI markers have failed so far. We demonstrate how high molecular variability and contamination problems limit the possibilities for barcoding using standard COI-based protocols in flatworms. As a consequence, molecular identification methods often rely on other widely applicable markers. In the case of Monogenea, a very diverse group of platyhelminth parasites, and Rhabdocoela, representing one-fourth of all free-living flatworm taxa, this has led to a relatively high availability of nuclear ITS and 18S/28S rDNA sequences on GenBank. In a comparison of the effectiveness in species assignment we conclude that mitochondrial and nuclear ribosomal markers perform equally well. In case intraspecific information is needed, rDNA sequences can guide the selection of the appropriate (i.e. taxon-specific COI primers if available.

The Inspector General's report on Nuclear Safety and Radiation Protection 2014

International Nuclear Information System (INIS)

2015-01-01

This report, written for the Chairman of EDF, gives the Inspector General's assessment of nuclear safety and radiation protection within the EDF Group. The report is also intended for all those in the company who contribute in any way to nuclear safety and radiation protection through their day-to-day actions and decisions. It also aims to identify any early warning signs and recommend areas for improvement. It therefore focuses on difficulties and weaknesses rather than strengths and progress. It is based on information gathered and observations made during the year, both in France and the UK, whether from workers in the field, or during visits to plants and meetings with the main stakeholders: managers, staff representatives, members of the medical profession, chairmen of local information commissions in France and of Site stakeholder groups (British equivalent of the French Local Information Commissions) in the UK, and contractors. It also makes use of visits and comparisons with other international players on the nuclear scene, and of dialogue with WANO (World Association of Nuclear Operators) and the nuclear safety authorities. Content: 1 - the Inspector General's view of 2014; 2- Contrasting trends in nuclear safety in different sets of plants; 3 - Making safety culture central to management; 4 - Towards an integrated approach to risk management; 5 - Relying on professional unified operations; 6 - The quest for robust maintenance; 7 - Nuclear engineering: a major asset for the operator; 8 - Nuclear managers - confidence builders; 9 - on course for reactor operation beyond 40 years in France; 10 - Service life challenges in the UK; 11 - Preparing the future: from the EPR to other new models; 12 - Noteworthy operational events; 13- Appendices: Results for the nuclear fleets (EDF SA, EDF Energy; Maps of the nuclear power plants(EDF SA, EDF Energy); Key dates for the nuclear units (EDF SA, EDF Energy); Abbreviations

Operating history of U.S. nuclear power reactors

International Nuclear Information System (INIS)

1974-01-01

The operating history of U. S. nuclear power plants through December 31, 1974 has been collected. Included are those nuclear reactor facilities which produce electricity, even if in token amounts, or which are part of a development program concerned with the generation of electricity through the use of a nuclear reactor as a heat source. The information is based on data furnished by facility operators. The charts are plotted in terms of cumulative thermal energy as a function of time. Since only those shutdowns of five days or more are shown, the charts do not give a detailed history of plant operation. They do, however, give an overview of the operating history of a variety of developmental and experimental nuclear power reactors. The data show the yearly gross generation of electricity for each U. S. nuclear plant and, for civilian power plants, information on reactor availability and plant capacity factor. (U.S.)

A Nuclear Energy Renaissance in the U.S.?

International Nuclear Information System (INIS)

Kessler, Carol E.; Mahy, Heidi A.; Ankrum, Al; Buelt, James L.; Branch, Kristi M.; Phillips, Jon R.

2008-01-01

Is it time for a nuclear energy renaissance? Among other things, nuclear power is a carbon neutral source of base load power. With the growth in energy use expected over the next 20 years and the growing negative impacts of global climate changes, the cost of oil and gas, energy security and diversity concerns, and progress on advanced reactor designs, it may be the right time for nuclear power to enter a new age of growth. Asia and Russia are both planning for a nuclear renaissance. In Europe, Finland and France have both taken steps to pursue new nuclear reactors. U.S. utilities are preparing for orders of new reactors; one submitted a request to the U.S. Nuclear Regulatory Commission (NRC) to review its request to construct a new reactor on an existing site. What has the industry been doing since nuclear energy was birthed in the 1960s? In those days a bold new industry boasted that nuclear power in the United States was going to be ''too cheap to meter'', but as we all know this did not come about for many reasons. Eventually, it became clear that industry had neglected to do its homework. Critiques of the industry were made on safety, security, environment, economic competitiveness (without government support), and nonproliferation. All of these factors need to be effectively addressed to promote the confidence and support of the public - without which a nuclear power program is not feasible.

Nuclear power generation: challenge in the 1980s

International Nuclear Information System (INIS)

Eklund, S.A.

1981-01-01

In the lecture ''Nuclear power generation - challenge in the 1980s'', attempt is made to predict the events arising in 1980s on the basis of the data available in the International Atomic Energy Agency. By the term ''challenge'', emphasis is placed on the potentiality of nuclear power for solving the world energy problem. This is indicated clearly by nuclear power currently accounting for 8%, of the total power generation in the world. The explanation in the above connection with figures and tables is made, including geographical distribution of reactors, nuclear power generation and total power generation in various countries, future capacity of nuclear power generation, situation of reactor operation, future installation of nuclear power plants, uranium demand/supply situation, spent fuel storage, etc. Then, discussion and analysis are made on such problems as waste management, economy, safety, and safeguards. (J.P.N.)

Cross sections for 12C+12C→12C(0+2)+12C(g.s.) using breathing mode doorways

International Nuclear Information System (INIS)

Ahmed, M.U.; Beres, W.P.

1982-01-01

A previously derived projection operator method is applied to the calculation of the cross section for 12 C+ 12 C→ 12 C(0 + 2 )+ 12 C(g.s.) with a breathing mode model being used to describe the 0 + 2 (7.68 MeV) state of 12 C. The relationship to processes leading to alpha particle channels is discussed. The cross section for 12 C+ 12 C→ 12 C(3 - )+ 12 C(g.s.) is also calculated and possible correlations with inelastic scattering to the 0 + 2 and 2 + states of 12 C are discussed. The results for both 0 + 2 and 3 - inelastic scattering are in reasonable agreement with experiment

Phylogenetic relationship of the Brazilian isolates of the rat lungworm Angiostrongylus cantonensis (Nematoda: Metastrongylidae employing mitochondrial COI gene sequence data

Directory of Open Access Journals (Sweden)

Monte Tainá CC

2012-11-01

Full Text Available Abstract Background The rat lungworm Angiostrongylus cantonensis can cause eosinophilic meningoencephalitis in humans. This nematode’s main definitive hosts are rodents and its intermediate hosts are snails. This parasite was first described in China and currently is dispersed across several Pacific islands, Asia, Australia, Africa, some Caribbean islands and most recently in the Americas. Here, we report the genetic variability among A. cantonensis isolates from different geographical locations in Brazil using mitochondrial cytochrome c oxidase subunit I (COI gene sequences. Methods The isolates of A. cantonensis were obtained from distinct geographical locations of Brazil. Genomic DNAs were extracted, amplified by polymerase reaction, purified and sequenced. A partial sequence of COI gene was determined to assess their phylogenetic relationship. Results The sequences of A. cantonensis were monophyletic. We identified a distinct clade that included all isolates of A. cantonensis from Brazil and Asia based on eight distinct haplotypes (ac1, ac2, ac3, ac4, ac5, ac6, ac7 and ac8 from a previous study. Interestingly, the Brazilian haplotype ac5 is clustered with isolates from Japan, and the Brazilian haplotype ac8 from Rio de Janeiro, São Paulo, Pará and Pernambuco states formed a distinct clade. There is a divergent Brazilian haplotype, which we named ac9, closely related to Chinese haplotype ac6 and Japanese haplotype ac7. Conclusion The genetic variation observed among Brazilian isolates supports the hypothesis that the appearance of A. cantonensis in Brazil is likely a result of multiple introductions of parasite-carrying rats, transported on ships due to active commerce with Africa and Asia during the European colonization period. The rapid spread of the intermediate host, Achatina fulica, also seems to have contributed to the dispersion of this parasite and the infection of the definitive host in different Brazilian regions.

Phylogenetic relationship of the Brazilian isolates of the rat lungworm Angiostrongylus cantonensis (Nematoda: Metastrongylidae) employing mitochondrial COI gene sequence data

Science.gov (United States)

2012-01-01

Background The rat lungworm Angiostrongylus cantonensis can cause eosinophilic meningoencephalitis in humans. This nematode’s main definitive hosts are rodents and its intermediate hosts are snails. This parasite was first described in China and currently is dispersed across several Pacific islands, Asia, Australia, Africa, some Caribbean islands and most recently in the Americas. Here, we report the genetic variability among A. cantonensis isolates from different geographical locations in Brazil using mitochondrial cytochrome c oxidase subunit I (COI) gene sequences. Methods The isolates of A. cantonensis were obtained from distinct geographical locations of Brazil. Genomic DNAs were extracted, amplified by polymerase reaction, purified and sequenced. A partial sequence of COI gene was determined to assess their phylogenetic relationship. Results The sequences of A. cantonensis were monophyletic. We identified a distinct clade that included all isolates of A. cantonensis from Brazil and Asia based on eight distinct haplotypes (ac1, ac2, ac3, ac4, ac5, ac6, ac7 and ac8) from a previous study. Interestingly, the Brazilian haplotype ac5 is clustered with isolates from Japan, and the Brazilian haplotype ac8 from Rio de Janeiro, São Paulo, Pará and Pernambuco states formed a distinct clade. There is a divergent Brazilian haplotype, which we named ac9, closely related to Chinese haplotype ac6 and Japanese haplotype ac7. Conclusion The genetic variation observed among Brazilian isolates supports the hypothesis that the appearance of A. cantonensis in Brazil is likely a result of multiple introductions of parasite-carrying rats, transported on ships due to active commerce with Africa and Asia during the European colonization period. The rapid spread of the intermediate host, Achatina fulica, also seems to have contributed to the dispersion of this parasite and the infection of the definitive host in different Brazilian regions. PMID:23130987

Status of Iran's nuclear program and negotiations

Energy Technology Data Exchange (ETDEWEB)

Albright, David [President, Institute for Science and International Security (ISIS), 236 Massachusetts Avenue, NE 305, Washington, DC 20002 (United States)

2014-05-09

Iran's nuclear program poses immense challenges to international security. Its gas centrifuge program has grown dramatically in the last several years, bringing Iran close to a point where it could produce highly enriched uranium in secret or declared gas centrifuge plants before its breakout would be discovered and stopped. To reduce the risk posed by Iran's nuclear program, the P5+1 have negotiated with Iran short term limits on the most dangerous aspects of its nuclear programs and is negotiating long-term arrangements that can provide assurance that Iran will not build nuclear weapons. These long-term arrangements need to include a far more limited and transparent Iranian nuclear program. In advance of arriving at a long-term arrangement, the IAEA will need to resolve its concerns about the alleged past and possibly on-going military dimensions of Iran's nuclear program.

Transduced PEP-1-ribosomal protein S3 (rpS3) ameliorates 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice

International Nuclear Information System (INIS)

Ahn, Eun Hee; Kim, Dae Won; Kang, Hye Won; Shin, Min Jae; Won, Moo Ho; Kim, Joon; Kim, Dong Joon; Kwon, Oh-Shin; Kang, Tae-Cheon; Han, Kyu Hyung; Park, Jinseu; Eum, Won Sik; Choi, Soo Young

2010-01-01

This study investigated the preventive effect of ribosomal protein S3 (rpS3) on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear edema in mice. A cell permeable expression vector PEP-1-rpS3 was constructed. Topical application of the vector markedly inhibited TPA-induced expression levels of cyclooxygenase-2 (COX-2) and pro-inflammatory cytokines. Application of PEP-1-rpS3 also resulted in a significant reduction in the activation of nuclear factor-kappa B (NF-kB) and mitogen-activated protein kinase (MAPK) in TPA-treated ears. These results indicate that PEP-1-rpS3 inhibits inflammatory response cytokines and enzymes by blocking NF-kB and MAPK, prompting the suggestion that PEP-1-rpS3 can be used as a therapeutic agent against skin inflammation.

The Swedish Nuclear Power Inspectorate's Review Statement and Evaluation of the Swedish Nuclear Fuel and Waste Management Co's RD and D Programme 2001

Energy Technology Data Exchange (ETDEWEB)

NONE

2002-09-01

According to the Act on Nuclear Activities, the holder of a licence to operate a nuclear reactor must adopt all necessary measures to manage and dispose of spent nuclear fuel and nuclear waste. The Act stipulates requirements on a research programme which is to be submitted to the competent regulatory authority once every three years. The Swedish Nuclear Power Inspectorate (SKI) is the competent authority that evaluates and reviews the programme. SKI distributes the programme to a wide circle of reviewing bodies for comment, including authorities, municipalities, universities and NGOs. The Swedish programme for final disposal of spent nuclear fuel started about 25 years ago. According to the Swedish Nuclear Waste Management Co. (SKB), the planned repository will not be closed until sometime in the 2050's. A series of decisions must be made before this goal is attained. The decision process can therefore be described as a multi-stage process. During each stages, safety will be evaluated and there is a possibility of taking additional time for development work or of selecting improved solutions. SKI's task is to ensure safety compliance throughout all of these stages. In its decision in January 2000, the Government explained that the Programme for Research, Development and Demonstration for the Treatment and Final Disposal of Nuclear Waste (RD and D Programme 98) complied with legislative requirements but that certain supplementary reporting should be conducted by SKB and submitted no later than when the next programme, in accordance with paragraph 12 of the Act on Nuclear Activities, was prepared (September 2001). The supplementary reporting requested by the Government, and which was submitted by SKB to SKI in December 2000, dealt with issues relating to method selection, site selection and the site investigation programme. SKI submitted its review of the supplement to the Government in June 2001 and the Government made a decision on the matter on November

Nuclear models to 200 MeV for high-energy data evaluations. Vol.12

International Nuclear Information System (INIS)

Chadwick, M.; Reffo, G.; Dunford, C.L.; Oblozinsky, P.

1998-01-01

The work of the Nuclear Energy Agency's Subgroup 12 is described, which represents a collaborative effort to summarize the current status of nuclear reaction modelling codes and prioritize desired future model improvements. Nuclear reaction modelling codes that use appropriate physics in the energy region up to 200 MeV are the focus of this study, particularly those that have proved useful in nuclear data evaluation work. This study is relevant to developing needs in accelerator-driven technology programs, which require accurate nuclear data to high energies for enhanced radiation transport simulations to guide engineering design. (author)

Africa's developing nuclear landscape holds potential for investors

Energy Technology Data Exchange (ETDEWEB)

Shepherd, John [nuclear 24, Brighton (United Kingdom)

2015-08-15

Africa is continuing to draw interest from potential nuclear investors as more of the region's nations consider the prospects for launching civil nuclear programmes. Much of the interest has been driven by South Africa, which announced its intention to push ahead with building a new fleet of nuclear power plants more than two years ago. South Africa's Department of Energy said it aims to select a ''strategic partner or partners'' for its planned new nuclear programme by the end of fiscal year 2015. The country's existing twin-unit Koeberg is the African continent's sole nuclear power plant, but expectations are high that this will change. According to 'The World Nuclear Supply Chain: Outlook 2030', released at the start of this year by the World Nuclear Association, Africa and Latin America could see investments of $ 20 billion (Euro 18.2 bn) and $ 14 billion, respectively over the next 15 years.

Nuclear critical opalescence and the M1 form factors of 12C and 13C

International Nuclear Information System (INIS)

Delorme, J.; Figureau, A.; Guichon, P.

1981-01-01

It is shown that core polarization by the nuclear pion field has opposite effects on the M1 form factors of 12 C(15.11 MeV) and 13 C(g.s.). New data on 13 C are found to agree with this prediction and a common interpretation of the experiments is shown to be possible for the two nuclei in terms of critical opalescence. Discrimination from alternative explanations of the observed anomalies should await further experiments, especially photopion reactions. (orig.)

Future of nuclear S&T in Canada

International Nuclear Information System (INIS)

Didsbury, R.

2015-01-01

'Full text:' Nuclear R&D started more than 70 years ago has led to establishment of successful nuclear industry and placed Canada among the ranks of Tier 1 nuclear nations with a full spectrum of capabilities and resources in nuclear technology. Recently, Canada's nuclear industry leaders endorsed a 25-year vision that sees Canada thriving as a Tier 1 nation; aligned, integrated trusted, and working collaboratively to deliver innovative, life-enhancing solutions for Canada and the world. The leaders have committed to realizing this longer-term vision through several actions including, commitment to support a strong Canadian nuclear science, technology and innovation agenda. Nuclear R&D in Canada will be largely informed and influenced by the international and domestic nuclear landscapes. Intergovernmental Panel on Climate Change (IPCC) recognizes the need for nuclear in stabilizing atmospheric carbon in ever growing demand for energy. In several industrialized and developing nations, new fleets of reactors are being built; with over 200 planned new constructions. International agencies and intergovernmental forums are engaged in several new collaborative initiatives including closing the back end of the fuel cycle, development of next generation safer and more efficient and small-modular reactor systems, improving nuclear safeguards and security measures, development of non-power applications, management of nuclear waste, reducing radiological exposures and responding to emergencies. Domestically, although there is no plan for a new build in the near- or medium-term, Ontario's Long-Term Energy Plan calls for maintaining nuclear contribution constant in the overall energy mix and the successful refurbishments will be a key to maintaining this mix. The Government has also undertaken restructuring of AECL to position the nuclear industry for success. There are potential opportunities for CANDU supply chain in the international market. The prototype

Future of nuclear S&T in Canada

Energy Technology Data Exchange (ETDEWEB)

Didsbury, R. [Canadian Nuclear Laboratories, Chalk River, Ontario (Canada)

2015-07-01

'Full text:' Nuclear R&D started more than 70 years ago has led to establishment of successful nuclear industry and placed Canada among the ranks of Tier 1 nuclear nations with a full spectrum of capabilities and resources in nuclear technology. Recently, Canada's nuclear industry leaders endorsed a 25-year vision that sees Canada thriving as a Tier 1 nation; aligned, integrated trusted, and working collaboratively to deliver innovative, life-enhancing solutions for Canada and the world. The leaders have committed to realizing this longer-term vision through several actions including, commitment to support a strong Canadian nuclear science, technology and innovation agenda. Nuclear R&D in Canada will be largely informed and influenced by the international and domestic nuclear landscapes. Intergovernmental Panel on Climate Change (IPCC) recognizes the need for nuclear in stabilizing atmospheric carbon in ever growing demand for energy. In several industrialized and developing nations, new fleets of reactors are being built; with over 200 planned new constructions. International agencies and intergovernmental forums are engaged in several new collaborative initiatives including closing the back end of the fuel cycle, development of next generation safer and more efficient and small-modular reactor systems, improving nuclear safeguards and security measures, development of non-power applications, management of nuclear waste, reducing radiological exposures and responding to emergencies. Domestically, although there is no plan for a new build in the near- or medium-term, Ontario's Long-Term Energy Plan calls for maintaining nuclear contribution constant in the overall energy mix and the successful refurbishments will be a key to maintaining this mix. The Government has also undertaken restructuring of AECL to position the nuclear industry for success. There are potential opportunities for CANDU supply chain in the international market. The prototype

The Inspector General's report on Nuclear Safety and Radiation Protection 2015

International Nuclear Information System (INIS)

2016-01-01

This report, written for the Chairman of EDF, gives the Inspector General's assessment of nuclear safety and radiation protection within the EDF Group. The report is also intended for all those in the company who contribute in any way to nuclear safety and radiation protection through their day-to-day actions and decisions. It also aims to identify any early warning signs and recommend areas for improvement. It therefore focuses on difficulties and weaknesses rather than strengths and progress. It is based on information gathered and observations made during the year, both in France and the UK, whether from workers in the field, or during visits to plants and meetings with the main stakeholders: managers, staff representatives, members of the medical profession, chairmen of local information commissions in France and of Site stakeholder groups (British equivalent of the French Local Information Commissions) in the UK, and contractors. It also makes use of visits and comparisons with other international players on the nuclear scene, and of dialogue with WANO (World Association of Nuclear Operators) and the nuclear safety authorities. Content: 1 - the Inspector General's view of 2015; 2 - Operational safety: mixed results; 3 - Nuclear safety clearly prioritised; 4 - Risk prevention: progress in France; 5 - Reinforced emergency preparedness post-Fukushima; 6 - Fire prevention: still a weak link; 7 - Continuous investment in training and careers; 8 - Using maintenance to leverage improved operational quality; 9 - Chemistry in France: a transition in need of strong support; 10 - Decommissioning projects are progressing; 11 - EPRs in China, France and the UK; 12 - Preparing for the future; 13 - A window on the world; 14 - Appendices: Results for the nuclear fleets (EDF SA, EDF Energy; Maps of the nuclear power plants(EDF SA, EDF Energy); Key dates for the nuclear units (EDF SA, EDF Energy); Abbreviations

The Inspector General's report on Nuclear Safety and Radiation Protection 2013

International Nuclear Information System (INIS)

2014-01-01

This report, written for the Chairman of EDF, gives the Inspector General's assessment of nuclear safety and radiation protection within the EDF Group. The report is also intended for all those in the company who contribute in any way to nuclear safety and radiation protection through their day-to-day actions and decisions. It also aims to identify any early warning signs and recommend areas for improvement. It therefore focuses on difficulties and weaknesses rather than strengths and progress. It is based on information gathered and observations made during the year, both in France and the UK, whether from workers in the field, or during visits to plants and meetings with the main stakeholders: managers, staff representatives, members of the medical profession, chairmen of local information commissions in France and of Site stakeholder groups (British equivalent of the French Local Information Commissions) in the UK, and contractors. It also makes use of visits and comparisons with other international players on the nuclear scene, and of dialogue with WANO (World Association of Nuclear Operators) and the nuclear safety authorities. Content: 1 - the Inspector General's view of 2013 2 - Safety in operation: good standing of results; 3 - Management of safety priority; 4 - Occupational safety: managers mobilization is necessary in France; 5 - Radiation protection: a new dynamics to initiate; 6 - Maintenance: regaining the essentials for the great careening; 7 - Fostering occupations to improve safety; 8 - A new momentum to the EPRs; 9 - Nuclear fuel, a major contribution to safety; 10 - Research-development: a lever to anticipate; 11 - Japan: safety under reconstruction; 12 - Noteworthy operational events; 13- Appendices: Results for the nuclear fleets (EDF SA, EDF Energy; Maps of the nuclear power plants(EDF SA, EDF Energy); Key dates for the nuclear units (EDF SA, EDF Energy); Abbreviations

China and Japan’s Strategic Nuclear Relationship

Science.gov (United States)

2009-09-01

Nuclear Numerology Chinese Style,” Arms Control Today (March, 2005); Robert S. Norris, “Chinese Nuclear Forces 2008,” Bulletin of the Atomic...Bulletin of the Atomic Scientists, May/June. ———. 2005. “Letters to the Editor: Nuclear Numerology Chinese Style,” Arms Control Today, March

The Nuclear Imperative in Russia’s Security Strategy

Directory of Open Access Journals (Sweden)

J. Oscar Alvarez Calzada

2005-10-01

Full Text Available The process which culminated in the disappearance of the USSR was heavily influenced by that Soviet Union’s inability to maintain the level of technology reached by the US in the arms race. Under the circumstances of deteriorating Russian power which have been developing since 1991, and given the precariousness that affects its armed forces, nuclear weapons have become the core element of the Russian Federation’s national security strategy. This article explores the causes that have led to this nuclear imperative in Russia’s security strategy; and secondly, it presents the most relevant, and worrying, consequence that this dependence has generated, which is the lowering of the threshold necessary forthe use of nuclear weapons.

Present Status of Nuclear Energy

Czech Academy of Sciences Publication Activity Database

Wagner, Vladimír

2013-01-01

Roč. 2013, SI (2013), s. 89-94 ISSN 0375-8842. [European Nuclear Forum. Praha, 12.05.2013-13.05.2013] Institutional support: RVO:61389005 Keywords : nuclear energy * nuclear reactors * electricity production Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders

Public's Cognitive and Emotional Responses to Nuclear Messages: Implications for Effective Nuclear Communication Programs

International Nuclear Information System (INIS)

Kim, Hyo Jung

2017-01-01

The public debate over the use of nuclear energy is not limited to the area of technology, and has become subject to the public's subjective perceptions and emotions regarding the issue. This study empirically demonstrated the advantage of loss framing in improving public's favorable responses toward nuclear energy messages. Such framing effect was found to be moderated by individuals' daily use of online news. The findings of this study suggest that public's cognitive and emotional responses toward nuclear messages should be carefully considered when planning effective nuclear communication program.

Russia's Nuclear Forces: Between Disarmament and Modernization

Energy Technology Data Exchange (ETDEWEB)

Podvig, Pavel

2011-04-01

Nuclear weapons have traditionally occupied an important place in Russia's national security strategy. This tradition goes back to the Soviet times, when the country invested considerable efforts into building its nuclear arsenal and achieving strategic parity with the United States. As Russia and the United States have been reducing their nuclear arsenals since the end of the Cold War, their relationship has undergone a complex transformation toward cooperation and partnership mixed with suspicion and rivalry. The focus of Russia's nuclear policy, however, has remained essentially unchanged - it still considers strategic balance with the United States to be an important element of national security and pays considerable attention to maintaining the deterrent potential of its strategic forces. Russia does recognize the emergence of new threats - it cannot ignore the threats related to regional instabilities and conflicts on its own territory and in bordering states, such as the tensions in the Caucasus or the war in Afghanistan, the terrorist activity that is associated with these conflicts, as well as the problems that stem from nuclear and missile proliferation. These, however, are not given a high priority in Russia's security policy. For example, the new military doctrine adopted in February 2010, opens the list of military threats with the expansion of geographical and political reach of NATO, which is followed by the threat to strategic stability and then by deployment of missile defense. Nuclear proliferation, terrorism, and destabilizing local conflicts are placed much further down the list. Even when it comes to confronting the issues of local instabilities and terrorism, Russia's leadership tends to see these issues through the prism of its strategic strength, alleging that terrorist attacks are a reaction to Russia's perceived weakness. This way of looking at the issues effectively redefines national security problems to conform

Women’s Participation in Africa’s Nuclear Development-Challenges and Opportunities (Poster Presentation)

International Nuclear Information System (INIS)

Mkhosi-Motsaathebe, M.

2015-01-01

Expansion of nuclear technologies and plans for new plants in Africa makes this an exciting time for more women to be involved in the nuclear sector and there are lots of opportunities across the nuclear value chain for women to be involved. In recent decades, more and more women are are now entering the nuclear field and many people are starting to recognise opportunities for women, since the role played by women in the nuclear field enhances the development goals for many countries. In developing countries and in Africa in particular, however, there is a greater need for awareness of women’s involvement in STEM fields in general, and to change prevailing attitudes about women’s participation in the nuclear science and technology in particular. This paper will look at various opportunities women have in the expanding nuclear sector in the continent, and how these opportunities can be utilised, not only for those in sciences but also in business disciplines. The approaches organizations and countries can take in broadening participation of the female gender in the nuclear development in Africa; will also be presented, as well as how to address the challenges faced by women in the dynamic nuclear field. (author)

Annual report - Industrias Nucleares do Brasil S A - 1998; Relatorio anual - Industrias Nucleares do Brasil S A - 1998

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-07-01

The annual report of 1998 of Industrias Nucleares do Brasil S A - Brazilian company responsible for the industrial activities of the nuclear fuel cycle - introduces the next main topics: mineral resource directory main actions; industrial directory main actions; finance and administration directory main actions; transparency; environment, safety and quality; the company; and financial statements.

Investing in Germany's nuclear expertise can reap international awards

Energy Technology Data Exchange (ETDEWEB)

Shepherd, John [nuclear 24, Brighton (United Kingdom)

2015-07-15

At the international expert conference, Annual Meeting on Nuclear Technology (AMNT 2015) in Berlin in May, there was a very welcome public admission from one of the German government's key policymakers. The director-general of the energy policy department at the Federal Ministry for Economic Affairs and Energy (Bundesministerium fuer Wirtschaft und Energie - BMWi), Thorsten Herdan, said the high level of expertise available throughout Germany's nuclear energy industry was greatly valued at home and abroad and must be retained. He rightly said that the country's technical competence and know-how ''will still be needed'' - despite the country's commitment to phasing out the use of nuclear at home under the politically-inspired 'energy transition' (Energiewende). The nuclear energy industry's commitment to identifying, training and nurturing a new generation of nuclear professionals is self evident. Perhaps what is needed now is for governments such as Germany's, whether supporters of nuclear power generation or not, to do more to endorse the importance of developing nuclear expertise. In the nuclear industry, governments will find a more than willing partner in supporting the training and education of the nuclear engineers and regulators of the future.

Record Management Audit: Nuclear Malaysia’s Experience

International Nuclear Information System (INIS)

Adnan, H.; Yusof, M. H.; Ngadiron, N.; Ismail, R.M.

2016-01-01

Full text: The Malaysian Nuclear Agency (Nuclear Malaysia) is heavily reliant on information in order to accomplish its strategic research and development, and commercialization (R&D&C) outcomes. Since its beginning in 1972, the activity of Information Management (IM) – Records Management (RM) is always integrated in the process of knowledge repository. The Division of Information Management (DIM) is the custodian for the agency’s knowledge repository and also responsible to ensure its compliance with the National Archive of Malaysian Act 2003 (Act 629), as well as to address the needs of 3s: Safety, Security and Safeguards outlined by IAEA. In 2013, Nuclear Malaysia has launched KM Nuclear Policy which includes KM audit committee, to oversee and provide checks and balances for KM initiative programmes. The first KM audit conducted was the Record Management Audit (RMA), started in 2014. The journey faced some challenges from people, process and technology and later completed in 2015 with accumulation of new knowledge derived for the KM improvement. RMA is a unique process which needs to be shared with others because it offers example and experience from the perspective of nuclear R&D agency. (author

New U.S. Nuclear Generation: 2010-2030

OpenAIRE

Geoffrey Rothwell

2010-01-01

The report's key finding is that new nuclear capacity in NEMS-RFF from 2015 to 2020 under the current levels of U.S. Department of Energy (DOE) loan guarantees is similar to the marginal increase in new capacity from lowering the nominal return-on-equity (ROE) in NEMS-RFF for new nuclear power from 17 to 14 percent. This equivalence allows for an analysis of the costs and benefits of increasing DOE loan guarantees to new nuclear plants.

The impact of the multilateral approach to the nuclear fuel cycle in Malaysia's nuclear fuel cycle policy

International Nuclear Information System (INIS)

Baharuddin, B.; Ferdinand, P.

2014-01-01

Since the Pakistan-India nuclear weapon race, the North Korean nuclear test and the September 11 attack revealed Abdul Qadeer Khan's clandestine nuclear black market and the fear that Iran's nuclear program may be used for nuclear weapon development, scrutiny of activities related to nuclear technologies, especially technology transfer has become more stringent. The nuclear supplier group has initiated a multilateral nuclear fuel cycle regime with the purpose of guaranteeing nuclear fuel supply and at the same time preventing the spread of nuclear proliferation. Malaysia wants to develop a programme for the peaceful use of nuclear energy and it needs to accommodate itself to this policy. When considering developing a nuclear fuel cycle policy, the key elements that Malaysia needs to consider are the extent of the fuel cycle technologies that it intends to acquire and the costs (financial and political) of acquiring them. Therefore, this paper will examine how the multilateral approach to the nuclear fuel cycle may influence Malaysia's nuclear fuel cycle policy, without jeopardising the country's rights and sovereignty as stipulated under the NPT. (authors)

The future of U.S.-Russia nuclear arms control

Science.gov (United States)

Pifer, Steven

2017-11-01

Nuclear arms control has long made contributions to U.S.-Soviet and U.S.-Russian security, but the current regime is at risk. The 1987 Intermediate-range Nuclear Forces Treaty may be headed for collapse. Both the United States and Russia are modernizing their strategic forces, and the fate of the 2010 New Strategic Arms Reduction Treaty is unclear. In the unlikely case that the sides are prepared to go beyond New START, there are ways to address further reductions and related issues. A collapse of the arms control regime, on the other hand, would mean the end of constraints on U.S. and Russian nuclear forces, a significant loss of transparency, and potential costs to U.S. security.

Collaborative development of Estonian nuclear master's program

Energy Technology Data Exchange (ETDEWEB)

Tkaczyk, A. H.; Kikas, A.; Realo, E.; Kirm, M.; Kiisk, M.; Isakar, K.; Suursoo, S.; Koch, R.; Feldbach, E.; Lushchik, A.; Reivelt, K. [Inst. of Physics, Univ. of Tartu, Riia 142, Tartu 51014 (Estonia)

2012-07-01

In 2009 Estonia approved the National Development Plan for the Energy Sector, including the nuclear energy option. This can be realized by construction of a nuclear power plant (NPP) in Estonia or by participation in neighboring nuclear projects (e.g., Lithuania and/or Finland). Either option requires the availability of competent personnel. It is necessary to prepare specialists with expertise in all aspects related to nuclear infrastructure and to meet workforce needs (e.g. energy enterprises, public agencies, municipalities). Estonia's leading institutions of higher education and research with the support of the European Social Fund have announced in this context a new nuclear master's curriculum to be developed. The language of instruction will be English. (authors)

Development of Risk Assessment Methodology for State's Nuclear Security Regime

Energy Technology Data Exchange (ETDEWEB)

Jang, Sung Soon; Seo, Hyung Min; Lee, Jung Ho; Kwak, Sung Woo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2011-05-15

Threats of nuclear terrorism are increasing after 9/11 terrorist attack. Treats include nuclear explosive device (NED) made by terrorist groups, radiological damage caused by a sabotage aiming nuclear facilities, and radiological dispersion device (RDD), which is also called 'dirty bomb'. In 9/11, Al Qaeda planed to cause radiological consequences by the crash of a nuclear power plant and the captured airplane. The evidence of a dirty bomb experiment was found in Afganistan by the UK intelligence agency. Thus, the international communities including the IAEA work substantial efforts. The leaders of 47 nations attended the 2010 nuclear security summit hosted by President Obama, while the next global nuclear summit will be held in Seoul, 2012. Most states established and are maintaining state's nuclear security regime because of the increasing threat and the international obligations. However, each state's nuclear security regime is different and depends on the state's environment. The methodology for the assessment of state's nuclear security regime is necessary to design and implement an efficient nuclear security regime, and to figure out weak points. The IAEA's INPRO project suggests a checklist method for State's nuclear security regime. The IAEA is now researching more quantitative methods cooperatively with several countries including Korea. In this abstract, methodologies to evaluate state's nuclear security regime by risk assessment are addressed

The Inspector General's report on Nuclear Safety and Radiation Protection 2008

International Nuclear Information System (INIS)

2009-01-01

This report, written for the Chairman of EDF, gives the Inspector General's assessment of nuclear safety and radiation protection within the EDF Group. The report is also intended for all those in the company who contribute in any way to nuclear safety and radiation protection through their day-to-day actions and decisions. It also aims to identify any early warning signs and recommend areas for improvement. It therefore focuses on difficulties and weaknesses rather than strengths and progress. It is based on information gathered and observations made during the year, both in France and the UK, whether from workers in the field, or during visits to plants and meetings with the main stakeholders: managers, staff representatives, members of the medical profession, chairmen of local information commissions in France and of Site stakeholder groups (British equivalent of the French Local Information Commissions) in the UK, and contractors. It also makes use of visits and comparisons with other international players on the nuclear scene, and of dialogue with WANO (World Association of Nuclear Operators) and the nuclear safety authorities. Content: 1 - the Inspector General's analysis and conclusions at the end of 2008; 2 - Nuclear safety management; 3 - Radiation protection; 4 - A changing relationship with the nuclear safety authority; 5 - Support for the nuclear plants in service; 6 - Succeeding with the EPR; 7 - Operating the installations for longer; 8 - Further opening up to the outside world; 9 - Renewal of skills; 10 - Labour relations; 11 - The driving forces of cultural change; 12 - Promote change and regulate its pace; 13 - The contribution of the medical staff; 14 - Relations with contractors; 15 - The fire hazard; 16 - Nuclear fuel; 17 - Decommissioning; 18 - Emergency response management; 19 - Events at EDF; 19.1 - The Tricastin nuclear power plant fuel assemblies; 19.2 - Steam generator behaviour; 19.3 - Reactor building evacuation; 20 - Visits

DNA barcodes identify Central Asian Colias butterflies (Lepidoptera, Pieridae).

Science.gov (United States)

Laiho, Juha; Ståhls, Gunilla

2013-12-30

A majority of the known Colias species (Lepidoptera: Pieridae, Coliadinae) occur in the mountainous regions of Central-Asia, vast areas that are hard to access, rendering the knowledge of many species limited due to the lack of extensive sampling. Two gene regions, the mitochondrial COI 'barcode' region and the nuclear ribosomal protein RpS2 gene region were used for exploring the utility of these DNA markers for species identification. A comprehensive sampling of COI barcodes for Central Asian Colias butterflies showed that the barcodes facilitated identification of most of the included species. Phylogenetic reconstruction based on parsimony and Neighbour-Joining recovered most species as monophyletic entities. For the RpS2 gene region species-specific sequences were registered for some of the included Colias spp. Nevertheless, this gene region was not deemed useful as additional molecular 'barcode'. A parsimony analysis of the combined COI and RpS2 data did not support the current subgeneric classification based on morphological characteristics.

The renewed spirit of Y-12

International Nuclear Information System (INIS)

Wall, David; Hassler, Morris; Parker, Elaine

2005-01-01

The Y-12 National Security Complex began operations in 1943 as a part of the Manhattan Project, the secret U.S. program that developed the first atomic weapon. With the end of the Cold War, the advent of the War on Terror, and the changing security needs of the US, Y-12 has begun to modernize and make changes to better meet the requirements of a smaller stockpile while supporting uranium supply needs and nuclear nonproliferation missions. Although we are proud of our place in history, after 60 years, we have begun to write a new chapter that will enable us to meet the new challenges facing the world today by strengthening our security posture and utilizing existing Y-12 expertise in nuclear nonproliferation initiatives. The modernization of Y-12 will enable us to be agile enough to adapt and respond to a much wider range of U.S. national security needs. As part of the National Nuclear Security Administration, nuclear nonproliferation has become one of the primary Y-12 missions. Some of the nuclear nonproliferation programs we support include the supply of low enriched uranium (LEU) to research and test reactors. The LEU provided to the research reactor community is derived from down blending highly enriched uranium (HEU) that is removed from dismantled nuclear weapons. Y-12 expertise has been used in numerous nonproliferation programs in Russia, the recent effort to remove material from Libya, and various activities supporting the new Global Threat Reduction Initiative (GTRI). The Y-12 National Security Complex stores significant quantities of HEU and therefore, has a security posture that must adapt to these new threats of global terrorism. This year, Y-12 has made real progress in modernizing its site so that it is better able to meet these new world challenges. Our modernization efforts will increase security, improve productivity, minimize health and safety risks and enable the Y-12 Site to continue to operate far into the future. This paper will summarize how

Scylla, Charaybdis, and the U.S. Nuclear Power Program

International Nuclear Information System (INIS)

Dragoumis, P.

1976-01-01

Like the Odysseus of Greek mythology, nuclear energy and therefore the energy security of the United States, is making a difficult passage through a strait lined with hazards. On one side is Scylla, the monster/rock hazard representing fear of nuclear power for its accident and proliferation risks. On the other side is Charybdis, a dangerous whirlpool characterizing the confusion and nuclear expansion-inhibiting uncertainty, created by inconsistent, unpredictable regulation, questions respecting international controls, closing the fuel cycle, enrichment, etc. Given the vital national U.S. stake in nuclear power, solutions to the problems inhibiting nuclear expansion must and will be found. While solutions are expected, acceleration of efforts is needed to assure a safe national course through the hazardous straits to U.S. energy security based on domestic sources

Q and A. Poland's progress on the road to new nuclear

Energy Technology Data Exchange (ETDEWEB)

Kraev, Kamen [NucNet, Brussels (Belgium)

2017-06-15

Conflicting reports have emerged from Poland about plans for its first reactors. Professor Grzegorz Wrochna of the Polish National Centre for Nuclear Research says the programme is on track and a business model is expected soon. The previous government's programme calls for 6 GW in two locations. The government recently published a strategy for responsible development which calls for the nuclear programme to be sped up. However, no capacity figures were included. The industry should not be bound by a rigid number. In time, maybe we will speak of 4 GW or 12 GW, but it will depend on market needs and financial possibilities. The biggest risks do not come from cancellation or public opinion. They come from delays.

Trends in U.S. nuclear standards development

International Nuclear Information System (INIS)

Crowley, J.H.; Kaminski, R.S.

1987-01-01

Regulation of the U.S Nuclear Power industry has been extensive during the 1970's. Key to this situation has been the evolution in the 'interpretation' of the rules, regulations and consensus standards which have been incorporated into NRC guidance documents by reference or endorsement. The resulting increase in the number and complexity of LWR construction requirements has significantly increased the labor content of an LWR construction project. The authors believe that existing nuclear related consensus standards should be reviewed with the objective of modifying the standards to improve the efficiency and productivity of engineering, craft, and non-manual personnel. (author)

Evaluation of neutron nuclear data for 12C

International Nuclear Information System (INIS)

Shibata, Keiichi

1983-12-01

Neutron nuclear data of 12 C have been evaluated for JENDL-3 in the energy range from 10 -5 eV to 20 MeV. Evaluated quantities are the total, elastic and inelastic scattering, radiative capture, photon-production, (n,p), (n,d) and (n,α) reaction cross sections and the angular or energy distribution of neutrons and photons. The total cross section below the threshold energy of the inelastic scattering has been calculated on the basis of the R-matrix theory. Three discrete levels have been taken into account for the inelastic scattering. (author)

Management of Spent Nuclear Fuel of Nuclear Research Reactor VVR-S at the National Institute of Physics and Nuclear Engineering, Bucharest, Romania

Science.gov (United States)

Biro, Lucian

2009-05-01

The Nuclear Research Reactor VVR-S (RR-VVR-S) located in Magurele-Bucharest, Romania, was designed for research and radioisotope production. It was commissioned in 1957 and operated without any event or accident for forty years until shut down in 1997. In 2002, by government decree, it was permanently shutdown for decommissioning. The National Institute of Physics and Nuclear Engineering (IFIN-HH) is responsible for decommissioning the RR-VVR-S, the first nuclear decommissioning project in Romania. In this context, IFIN-HH prepared and obtained approval from the Romanian Nuclear Regulatory Body for the Decommissioning Plan. One of the most important aspects for decommissioning the RR-VVR-S is solving the issue of the fresh and spent nuclear fuel (SNF) stored on site in wet storage pools. In the framework of the Russian Research Reactor Fuel Return Program (RRRFR), managed by the U.S. Department of Energy and in cooperation with the International Atomic Energy Agency and the Rosatom State Corporation, Romania repatriated all fresh HEU fuel to the Russian Federation in 2003 and the HEU SNF will be repatriated to Russia in 2009. With the experience and lessons learned from this action and with the financial support of the Romanian Government it will be possible for Romania to also repatriate the LEU SNF to the Russian Federation before starting the dismantling and decontamination of the nuclear facility. [4pt] In collaboration with K. Allen, Idaho National Laboratory, USA; L. Biro, National Commission for Nuclear Activities Control, Romania; and M. Dragusin, National Institute of Physics and Nuclear Engineering, Bucharest-Magurele, Romania.

Opaque Nuclear Strategy

Science.gov (United States)

2017-12-01

Relationship, 0000271219, 1961. https://www.cia.gov/ library / readingroom/docs/DOC_0000271219.pdf. . Trends in South Africa’s Nuclear Security Policies ...official policy or position of the Department of Defense or the U.S. Government. IRB number ____N/A____. 12a. DISTRIBUTION / AVAILABILITY STATEMENT...how Israel and South Africa shaped those strategies. This research may contribute to better understanding possible policies of potential nuclear

Electric quadrupole interactions on /sup 12/B and /sup 12/N implanted in Mg studied by nuclear depolarization due to level mixing

Energy Technology Data Exchange (ETDEWEB)

Tanihata, I; Kogo, S; Sugimoto, K [Osaka Univ., Toyonaka (Japan). Lab. of Nuclear Studies

1977-04-25

Electric quadrupole interactions on polarized /sup 12/B and /sup 12/N implanted in a Mg single crystal have been studied by a new method in which the nuclear depolarization due to level mixing caused by an external magnetic field is detected.

Analysis of nuclear stimulation of Reservoir A, U.S.S.R

International Nuclear Information System (INIS)

Howard, J.H.

1972-01-01

Following stimulation by three nuclear explosives, the field rate of production of ''Reservoir A'', U.S.S.R., increased very significantly. The potential profitability of projects such as Reservoir A and some of the possible causes for the increased rate of production are reviewed

Pycnonuclear 12C+12C reaction at zero temperature

International Nuclear Information System (INIS)

Gasques, L R; Beard, M; Chamon, L C; Wiescher, M

2005-01-01

We present pycnonuclear reaction calculations for a one-component ionic crystal at zero temperature considering different theoretical approaches. The rates depend directly on the determination of the astrophysical S-factor at low energies, which has been obtained through the barrier penetration formalism. A totally parameter-free model for the real part of the nuclear interaction has been employed in the calculation of 12 C+ 12 C fusion cross sections

Report of the international forum on nuclear energy, nuclear non-proliferation and nuclear security. Measures to ensure nuclear non-proliferation and nuclear security for the back end of nuclear fuel cycle and regional cooperation in Asia

International Nuclear Information System (INIS)

Tazaki, Makiko; Yamamura, Tsukasa; Suzuki, Mitsutoshi; Kuno, Yusuke; Mochiji, Toshiro

2013-03-01

The Japan Atomic Energy Agency (JAEA) held 'International Forum on Nuclear Energy, Nuclear Non-proliferation and Nuclear Security - Measures to ensure nuclear non-proliferation and nuclear security for the back end of nuclear fuel cycle and regional cooperation in Asia-' on 12 and 13 December 2012, co-hosted by the Japan Institute of International Affairs (JIIA) and School of Engineering, The University of Tokyo. In the forum, keynote speakers from Japan, International Atomic Energy Agency (IAEA), the U.S., France and Republic of Korea (ROK), respectively explained their efforts regarding peaceful use of nuclear energy and nuclear non-proliferation. In two panel discussions, entitled 'Measures to ensure nuclear non-proliferation and nuclear security of nuclear fuel cycle back end' and 'Measures to ensure nuclear non-proliferation and nuclear security for nuclear energy use in the Asian region and a multilateral cooperative framework', active discussions were made among panelists from Japan, IAEA, the U.S., France, ROK, Russia and Kazakhstan. This report includes abstracts of keynote speeches, summaries of two panel discussions and materials of the presentations in the forum. The editors take full responsibility for the wording and content of this report except presentation materials. (author)

Near-Term Nuclear Power Revival? A U.S. and International Perspective

International Nuclear Information System (INIS)

Braun, C.

2004-01-01

In this paper I review the causes for the renewed interest in the near-term revival of nuclear power in the U.S. and internationally. I comment on the progress already made in the U.S. in restarting a second era of commercial nuclear power plant construction, and on what is required going forwards, from a utilities perspective, to commit to and implement new plant orders. I review the specific nuclear projects discussed and committed to in the U.S. and abroad in terms of utilities, sites, vendor and suppliers teams, and project arrangements. I will then offer some tentative conclusions regarding the prospects for a near-term U.S. and global nuclear power revival

International development of Japan's Nuclear Industry. Indispensable Japan-U.S. cooperation

International Nuclear Information System (INIS)

Saigo, Masao

2006-01-01

It is significant to internationally develop the nuclear power plants technology that has been fostered by Japan's nuclear industry. It is also important to work with taking the degree of development of nuclear power plants of the recipient country into consideration. ''Forum on International Development of Nuclear Industry'' organized by the Japan Atomic Industrial Forum, Inc. (JAIF) proposed it would be indispensable for a Japan's nuclear industry to establish a Japan-U.S. Cooperation with the support of Government in order to develop the nuclear technology internationally. In November 2005, the investigating team including utilities and nuclear industry visited U.S. and exchanged opinions on its possibility. Investigating results and their evaluation were described. (T.Tanaka)

Iran's nuclear program - for power generation or nuclear weapons?; Irans kjernefysiske program - for kraftproduksjon eller kjernevaapen?

Energy Technology Data Exchange (ETDEWEB)

Kippe, Halvor

2008-11-15

This report addresses the development of a nuclear infrastructure in Iran, and assessments are made on the near-term potential this infrastructure might yield of either nuclear power or nuclear arms production. The most significant facilities are treated in a more elaborate fashion, as these are assumed to have key roles in either a true civilian programme, or in the prospect of weapons-grade fissile material production. The future potential capacity for the latter is calculated under certain presumptions, both in the case that Iran focuses its efforts on uranium-based nuclear weapons, and in the case that it should choose the plutonium path to nuclear weapons. All the conclusions and findings in this report are based on technological considerations. This means that social or political assessments have not prevailed, rather the picture of Iran's nuclear programme is drawn through descriptions and assessments of facilities and systems, and their role in the bigger context. Definite conclusions have not been made as to whether Iran's nuclear programme currently is aimed towards nuclear arms or nuclear power. The secrecy surrounding some of the most prominent nuclear sites together with more or less credible allegations of purely weapons-related activities in the past, make it hard not to conclude that Iran until the disclosures in 2002 made as great an effort as it could on its way on developing nuclear weapons covertly. The scope of today's nuclear programme seems, on the other hand, most likely to be in part to help relieve the ever-increasing need for energy, although considerable deficits to this strategy are identified, at the same time as the Iranian people are united in a giant, high-prestige project in defiance of massive international pressure. Adding to this is a much-feared ability to rapidly being able to redirect their nuclear efforts, and develop nuclear arms in perhaps as little as one year. This so-called break-out scenario, where Iran

India’s Evolving Nuclear Force and Its Implications for U.S. Strategy in the Asia-Pacific

Science.gov (United States)

2016-06-01

development and the norms of restraint in the present nuclear doctrine. Conclusion. The growing diversity of India’s delivery vehicles generates questions...India has reportedly rejected such proposals due to reasoning that its nuclear force must also be built to deter China and cannot be capped sole- ly...security policy formulation. iii v Strategic Studies Institute and U.S. Army War College Press INDIA’S EVOLVING NUCLEAR FORCE AND ITS IMPLICATIONS FOR

Molecular identification of sibling species of Sclerodermus (Hymenoptera: Bethylidae that parasitize buprestid and cerambycid beetles by using partial sequences of mitochondrial DNA cytochrome oxidase subunit 1 and 28S ribosomal RNA gene.

Directory of Open Access Journals (Sweden)

Yuan Jiang

Full Text Available The species belonging to Sclerodermus (Hymenoptera: Bethylidae are currently the most important insect natural enemies of wood borer pests, mainly buprestid and cerambycid beetles, in China. However, some sibling species of this genus are very difficult to distinguish because of their similar morphological features. To address this issue, we conducted phylogenetic and genetic analyses of cytochrome oxidase subunit I (COI and 28S RNA gene sequences from eight species of Sclerodermus reared from different wood borer pests. The eight sibling species were as follows: S. guani Xiao et Wu, S. sichuanensis Xiao, S. pupariae Yang et Yao, and Sclerodermus spp. (Nos. 1-5. A 594-bp fragment of COI and 750-bp fragment of 28S were subsequently sequenced. For COI, the G-C content was found to be low in all the species, averaging to about 30.0%. Sequence divergences (Kimura-2-parameter distances between congeneric species averaged to 4.5%, and intraspecific divergences averaged to about 0.09%. Further, the maximum sequence divergences between congeneric species and Sclerodermus sp. (No. 5 averaged to about 16.5%. All 136 samples analyzed were included in six reciprocally monophyletic clades in the COI neighbor-joining (NJ tree. The NJ tree inferred from the 28S rRNA sequence yielded almost identical results, but the samples from S. guani, S. sichuanensis, S. pupariae, and Sclerodermus spp. (Nos. 1-4 clustered together and only Sclerodermus sp. (No. 5 clustered separately. Our findings indicate that the standard barcode region of COI can be efficiently used to distinguish morphologically similar Sclerodermus species. Further, we speculate that Sclerodermus sp. (No. 5 might be a new species of Sclerodermus.

China: Suspected Acquisition of U.S. Nuclear Weapon Secrets

National Research Council Canada - National Science Library

Kan, Shirley A

2006-01-01

... of U.S. nuclear weapon secrets in its development of nuclear forces, as well as whether the Administration's response to the security problems was effective or mishandled and whether it fairly used or abused...

Measurement of D$^+_s$ production and nuclear modification factor in Pb–Pb collisions at $\\sqrt{s_{\\rm NN}} = 2.76$ TeV

CERN Document Server

Adam, Jaroslav; Aggarwal, Madan Mohan; Aglieri Rinella, Gianluca; Agnello, Michelangelo; Agrawal, Neelima; Ahammed, Zubayer; Ahn, Sang Un; Aiola, Salvatore; Akindinov, Alexander; Alam, Sk Noor; Aleksandrov, Dmitry; Alessandro, Bruno; Alexandre, Didier; Alfaro Molina, Jose Ruben; Alici, Andrea; Alkin, Anton; Millan Almaraz, Jesus Roberto; Alme, Johan; Alt, Torsten; Altinpinar, Sedat; Altsybeev, Igor; Alves Garcia Prado, Caio; Andrei, Cristian; Andronic, Anton; Anguelov, Venelin; Anielski, Jonas; Anticic, Tome; Antinori, Federico; Antonioli, Pietro; Aphecetche, Laurent Bernard; Appelshaeuser, Harald; Arcelli, Silvia; Arnaldi, Roberta; Arnold, Oliver Werner; Arsene, Ionut Cristian; Arslandok, Mesut; Audurier, Benjamin; Augustinus, Andre; Averbeck, Ralf Peter; Azmi, Mohd Danish; Badala, Angela; Baek, Yong Wook; Bagnasco, Stefano; Bailhache, Raphaelle Marie; Bala, Renu; Baldisseri, Alberto; Baral, Rama Chandra; Barbano, Anastasia Maria; Barbera, Roberto; Barile, Francesco; Barnafoldi, Gergely Gabor; Barnby, Lee Stuart; Ramillien Barret, Valerie; Bartalini, Paolo; Barth, Klaus; Bartke, Jerzy Gustaw; Bartsch, Esther; Basile, Maurizio; Bastid, Nicole; Basu, Sumit; Bathen, Bastian; Batigne, Guillaume; Batista Camejo, Arianna; Batyunya, Boris; Batzing, Paul Christoph; Bearden, Ian Gardner; Beck, Hans; Bedda, Cristina; Behera, Nirbhay Kumar; Belikov, Iouri; Bellini, Francesca; Bello Martinez, Hector; Bellwied, Rene; Belmont Iii, Ronald John; Belmont Moreno, Ernesto; Belyaev, Vladimir; Bencedi, Gyula; Beole, Stefania; Berceanu, Ionela; Bercuci, Alexandru; Berdnikov, Yaroslav; Berenyi, Daniel; Bertens, Redmer Alexander; Berzano, Dario; Betev, Latchezar; Bhasin, Anju; Bhat, Inayat Rasool; Bhati, Ashok Kumar; Bhattacharjee, Buddhadeb; Bhom, Jihyun; Bianchi, Livio; Bianchi, Nicola; Bianchin, Chiara; Bielcik, Jaroslav; Bielcikova, Jana; Bilandzic, Ante; Biswas, Rathijit; Biswas, Saikat; Bjelogrlic, Sandro; Blair, Justin Thomas; Blau, Dmitry; Blume, Christoph; Bock, Friederike; Bogdanov, Alexey; 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De Cataldo, Giacinto; De Conti, Camila; De Cuveland, Jan; De Falco, Alessandro; De Gruttola, Daniele; De Marco, Nora; De Pasquale, Salvatore; Deisting, Alexander; Deloff, Andrzej; Denes, Ervin Sandor; Deplano, Caterina; Dhankher, Preeti; Di Bari, Domenico; Di Mauro, Antonio; Di Nezza, Pasquale; Diaz Corchero, Miguel Angel; Dietel, Thomas; Dillenseger, Pascal; Divia, Roberto; Djuvsland, Oeystein; Dobrin, Alexandru Florin; Domenicis Gimenez, Diogenes; Donigus, Benjamin; Dordic, Olja; Drozhzhova, Tatiana; Dubey, Anand Kumar; Dubla, Andrea; Ducroux, Laurent; Dupieux, Pascal; Ehlers Iii, Raymond James; Elia, Domenico; Engel, Heiko; Epple, Eliane; Erazmus, Barbara Ewa; Erdemir, Irem; Erhardt, Filip; Espagnon, Bruno; Estienne, Magali Danielle; Esumi, Shinichi; Eum, Jongsik; Evans, David; Evdokimov, Sergey; Eyyubova, Gyulnara; Fabbietti, Laura; Fabris, Daniela; Faivre, Julien; Fantoni, Alessandra; Fasel, Markus; Feldkamp, Linus; Feliciello, Alessandro; Feofilov, Grigorii; Ferencei, Jozef; Fernandez Tellez, Arturo; Gonzalez Ferreiro, Elena; Ferretti, Alessandro; Festanti, Andrea; Feuillard, Victor Jose Gaston; Figiel, Jan; Araujo Silva Figueredo, Marcel; Filchagin, Sergey; Finogeev, Dmitry; Fionda, Fiorella; Fiore, Enrichetta Maria; Fleck, Martin Gabriel; Floris, Michele; Foertsch, Siegfried Valentin; Foka, Panagiota; Fokin, Sergey; Fragiacomo, Enrico; Francescon, Andrea; Frankenfeld, Ulrich Michael; Fuchs, Ulrich; Furget, Christophe; Furs, Artur; Fusco Girard, Mario; Gaardhoeje, Jens Joergen; Gagliardi, Martino; Gago Medina, Alberto Martin; Gallio, Mauro; Gangadharan, Dhevan Raja; Ganoti, Paraskevi; Gao, Chaosong; Garabatos Cuadrado, Jose; Garcia-Solis, Edmundo Javier; Gargiulo, Corrado; Gasik, Piotr Jan; Gauger, Erin Frances; Germain, Marie; Gheata, Andrei George; Gheata, Mihaela; Ghosh, Premomoy; Ghosh, Sanjay Kumar; Gianotti, Paola; Giubellino, Paolo; Giubilato, Piero; Gladysz-Dziadus, Ewa; Glassel, Peter; Gomez Coral, Diego Mauricio; Gomez Ramirez, Andres; Gonzalez, Victor; Gonzalez Zamora, Pedro; Gorbunov, Sergey; Gorlich, Lidia Maria; Gotovac, Sven; Grabski, Varlen; Grachov, Oleg Anatolievich; Graczykowski, Lukasz Kamil; Graham, Katie Leanne; Grelli, Alessandro; Grigoras, Alina Gabriela; Grigoras, Costin; Grigoryev, Vladislav; Grigoryan, Ara; Grigoryan, Smbat; Grynyov, Borys; Grion, Nevio; Gronefeld, Julius Maximilian; Grosse-Oetringhaus, Jan Fiete; Grossiord, Jean-Yves; Grosso, Raffaele; Guber, Fedor; Guernane, Rachid; Guerzoni, Barbara; Gulbrandsen, Kristjan Herlache; Gunji, Taku; Gupta, Anik; Gupta, Ramni; Haake, Rudiger; Haaland, Oystein Senneset; Hadjidakis, Cynthia Marie; Haiduc, Maria; Hamagaki, Hideki; Hamar, Gergoe; Harris, John William; Harton, Austin Vincent; Hatzifotiadou, Despina; Hayashi, Shinichi; Heckel, Stefan Thomas; Heide, Markus Ansgar; Helstrup, Haavard; Herghelegiu, Andrei Ionut; Herrera Corral, Gerardo Antonio; Hess, Benjamin Andreas; Hetland, Kristin Fanebust; Hillemanns, Hartmut; Hippolyte, Boris; Hosokawa, Ritsuya; Hristov, Peter Zahariev; Huang, Meidana; 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La Rocca, Paola; Ladron De Guevara, Pedro; Lagana Fernandes, Caio; Lakomov, Igor; Langoy, Rune; Lara Martinez, Camilo Ernesto; Lardeux, Antoine Xavier; Lattuca, Alessandra; Laudi, Elisa; Lea, Ramona; Leardini, Lucia; Lee, Graham Richard; Lee, Seongjoo; Lehas, Fatiha; Lemmon, Roy Crawford; Lenti, Vito; Leogrande, Emilia; Leon Monzon, Ildefonso; Leon Vargas, Hermes; Leoncino, Marco; Levai, Peter; Li, Shuang; Li, Xiaomei; Lien, Jorgen Andre; Lietava, Roman; Lindal, Svein; Lindenstruth, Volker; Lippmann, Christian; Lisa, Michael Annan; Ljunggren, Hans Martin; Lodato, Davide Francesco; Lonne, Per-Ivar; Loginov, Vitaly; Loizides, Constantinos; Lopez, Xavier Bernard; Lopez Torres, Ernesto; Lowe, Andrew John; Luettig, Philipp Johannes; Lunardon, Marcello; Luparello, Grazia; Maevskaya, Alla; Mager, Magnus; Mahajan, Sanjay; Mahmood, Sohail Musa; Maire, Antonin; Majka, Richard Daniel; Malaev, Mikhail; Maldonado Cervantes, Ivonne Alicia; Malinina, Liudmila; Mal'Kevich, Dmitry; Malzacher, Peter; Mamonov, Alexander; Manko, Vladislav; Manso, Franck; Manzari, Vito; Marchisone, Massimiliano; Mares, Jiri; Margagliotti, Giacomo Vito; Margotti, Anselmo; Margutti, Jacopo; Marin, Ana Maria; Markert, Christina; Marquard, Marco; Martin, Nicole Alice; Martin Blanco, Javier; Martinengo, Paolo; Martinez Hernandez, Mario Ivan; Martinez-Garcia, Gines; Martinez Pedreira, Miguel; Mas, Alexis Jean-Michel; Masciocchi, Silvia; Masera, Massimo; Masoni, Alberto; Massacrier, Laure Marie; Mastroserio, Annalisa; Matyja, Adam Tomasz; Mayer, Christoph; Mazer, Joel Anthony; Mazzoni, Alessandra Maria; Mcdonald, Daniel; Meddi, Franco; Melikyan, Yuri; Menchaca-Rocha, Arturo Alejandro; Meninno, Elisa; Mercado-Perez, Jorge; Meres, Michal; Miake, Yasuo; Mieskolainen, Matti Mikael; Mikhaylov, Konstantin; Milano, Leonardo; Milosevic, Jovan; Minervini, Lazzaro Manlio; Mischke, Andre; Mishra, Aditya Nath; Miskowiec, Dariusz Czeslaw; Mitra, Jubin; Mitu, Ciprian Mihai; Mohammadi, Naghmeh; Mohanty, Bedangadas; Molnar, Levente; Montano Zetina, Luis Manuel; Montes Prado, Esther; Moreira De Godoy, Denise Aparecida; Perez Moreno, Luis Alberto; Moretto, Sandra; Morreale, Astrid; Morsch, Andreas; Muccifora, Valeria; Mudnic, Eugen; Muhlheim, Daniel Michael; Muhuri, Sanjib; Mukherjee, Maitreyee; Mulligan, James Declan; Gameiro Munhoz, Marcelo; Munzer, Robert Helmut; Murray, Sean; Musa, Luciano; Musinsky, Jan; Naik, Bharati; Nair, Rahul; Nandi, Basanta Kumar; Nania, Rosario; Nappi, Eugenio; Naru, Muhammad Umair; Ferreira Natal Da Luz, Pedro Hugo; Nattrass, Christine; Nayak, Kishora; Nayak, Tapan Kumar; Nazarenko, Sergey; Nedosekin, Alexander; Nellen, Lukas; Ng, Fabian; Nicassio, Maria; Niculescu, Mihai; Niedziela, Jeremi; Nielsen, Borge Svane; Nikolaev, Sergey; Nikulin, Sergey; Nikulin, Vladimir; Noferini, Francesco; Nomokonov, Petr; Nooren, Gerardus; Cabanillas Noris, Juan Carlos; Norman, Jaime; Nyanin, Alexander; Nystrand, Joakim Ingemar; Oeschler, Helmut Oskar; Oh, Saehanseul; Oh, Sun Kun; Ohlson, Alice Elisabeth; Okatan, Ali; Okubo, Tsubasa; Olah, Laszlo; Oleniacz, Janusz; Oliveira Da Silva, Antonio Carlos; Oliver, Michael Henry; Onderwaater, Jacobus; Oppedisano, Chiara; Orava, Risto; Ortiz Velasquez, Antonio; Oskarsson, Anders Nils Erik; Otwinowski, Jacek Tomasz; Oyama, Ken; Ozdemir, Mahmut; Pachmayer, Yvonne Chiara; Pagano, Paola; Paic, Guy; Pal, Susanta Kumar; Pan, Jinjin; Pandey, Ashutosh Kumar; Papcun, Peter; Papikyan, Vardanush; Pappalardo, Giuseppe; Pareek, Pooja; Park, Woojin; Parmar, Sonia; Passfeld, Annika; Paticchio, Vincenzo; Patra, Rajendra Nath; Paul, Biswarup; Peitzmann, Thomas; Pereira Da Costa, Hugo Denis Antonio; Pereira De Oliveira Filho, Elienos; Peresunko, Dmitry Yurevich; Perez Lara, Carlos Eugenio; Perez Lezama, Edgar; Peskov, Vladimir; Pestov, Yury; Petracek, Vojtech; Petrov, Viacheslav; Petrovici, Mihai; Petta, Catia; Piano, Stefano; Pikna, Miroslav; Pillot, Philippe; Pinazza, Ombretta; Pinsky, Lawrence; Piyarathna, Danthasinghe; Ploskon, Mateusz Andrzej; Planinic, Mirko; Pluta, Jan Marian; Pochybova, Sona; Podesta Lerma, Pedro Luis Manuel; Poghosyan, Martin; Polishchuk, Boris; Poljak, Nikola; Poonsawat, Wanchaloem; Pop, Amalia; Porteboeuf, Sarah Julie; Porter, R Jefferson; Pospisil, Jan; Prasad, Sidharth Kumar; Preghenella, Roberto; Prino, Francesco; Pruneau, Claude Andre; Pshenichnov, Igor; Puccio, Maximiliano; Puddu, Giovanna; Pujahari, Prabhat Ranjan; Punin, Valery; Putschke, Jorn Henning; Qvigstad, Henrik; Rachevski, Alexandre; Raha, Sibaji; Rajput, Sonia; Rak, Jan; Rakotozafindrabe, Andry Malala; Ramello, Luciano; Rami, Fouad; Raniwala, Rashmi; Raniwala, Sudhir; Rasanen, Sami Sakari; Rascanu, Bogdan Theodor; Rathee, Deepika; Read, Kenneth Francis; Redlich, Krzysztof; Reed, Rosi Jan; Rehman, Attiq Ur; Reichelt, Patrick Simon; Reidt, Felix; Ren, Xiaowen; Renfordt, Rainer Arno Ernst; Reolon, Anna Rita; Reshetin, Andrey; Revol, Jean-Pierre; Reygers, Klaus Johannes; Riabov, Viktor; Ricci, Renato Angelo; Richert, Tuva Ora Herenui; Richter, Matthias Rudolph; Riedler, Petra; Riegler, Werner; Riggi, Francesco; Ristea, Catalin-Lucian; Rocco, Elena; Rodriguez Cahuantzi, Mario; Rodriguez Manso, Alis; Roeed, Ketil; Rogochaya, Elena; Rohr, David Michael; Roehrich, Dieter; Romita, Rosa; Ronchetti, Federico; Ronflette, Lucile; Rosnet, Philippe; Rossi, Andrea; Roukoutakis, Filimon; Roy, Ankhi; Roy, Christelle Sophie; Roy, Pradip Kumar; Rubio Montero, Antonio Juan; Rui, Rinaldo; Russo, Riccardo; Ryabinkin, Evgeny; Ryabov, Yury; Rybicki, Andrzej; Sadovskiy, Sergey; Safarik, Karel; Sahlmuller, Baldo; Sahoo, Pragati; Sahoo, Raghunath; Sahoo, Sarita; Sahu, Pradip Kumar; Saini, Jogender; Sakai, Shingo; Saleh, Mohammad Ahmad; Salzwedel, Jai Samuel Nielsen; Sambyal, Sanjeev Singh; Samsonov, Vladimir; Sandor, Ladislav; Sandoval, Andres; Sano, Masato; Sarkar, Debojit; Scapparone, Eugenio; Scarlassara, Fernando; Schiaua, Claudiu Cornel; Schicker, Rainer Martin; Schmidt, Christian Joachim; Schmidt, Hans Rudolf; Schuchmann, Simone; Schukraft, Jurgen; Schulc, Martin; Schuster, Tim Robin; Schutz, Yves Roland; Schwarz, Kilian Eberhard; Schweda, Kai Oliver; Scioli, Gilda; Scomparin, Enrico; Scott, Rebecca Michelle; Sefcik, Michal; Seger, Janet Elizabeth; Sekiguchi, Yuko; Sekihata, Daiki; Selyuzhenkov, Ilya; Senosi, Kgotlaesele; Senyukov, Serhiy; Serradilla Rodriguez, Eulogio; Sevcenco, Adrian; Shabanov, Arseniy; Shabetai, Alexandre; Shadura, Oksana; Shahoyan, Ruben; Shangaraev, Artem; Sharma, Ankita; Sharma, Mona; Sharma, Monika; Sharma, Natasha; Shigaki, Kenta; Shtejer Diaz, Katherin; Sibiryak, Yury; Siddhanta, Sabyasachi; Sielewicz, Krzysztof Marek; Siemiarczuk, Teodor; Silvermyr, David Olle Rickard; Silvestre, Catherine Micaela; Simatovic, Goran; Simonetti, Giuseppe; Singaraju, Rama Narayana; Singh, Ranbir; Singha, Subhash; Singhal, Vikas; Sinha, Bikash; Sarkar - Sinha, Tinku; Sitar, Branislav; Sitta, Mario; Skaali, Bernhard; Slupecki, Maciej; Smirnov, Nikolai; Snellings, Raimond; Snellman, Tomas Wilhelm; Soegaard, Carsten; Song, Jihye; Song, Myunggeun; Song, Zixuan; Soramel, Francesca; Sorensen, Soren Pontoppidan; Sozzi, Federica; Spacek, Michal; Spiriti, Eleuterio; Sputowska, Iwona Anna; Spyropoulou-Stassinaki, Martha; Stachel, Johanna; Stan, Ionel; Stefanek, Grzegorz; Stenlund, Evert Anders; Steyn, Gideon Francois; Stiller, Johannes Hendrik; Stocco, Diego; Strmen, Peter; Alarcon Do Passo Suaide, Alexandre; Sugitate, Toru; Suire, Christophe Pierre; Suleymanov, Mais Kazim Oglu; Suljic, Miljenko; Sultanov, Rishat; Sumbera, Michal; Szabo, Alexander; Szanto De Toledo, Alejandro; Szarka, Imrich; Szczepankiewicz, Adam; Szymanski, Maciej Pawel; Tabassam, Uzma; Takahashi, Jun; Tambave, Ganesh Jagannath; Tanaka, Naoto; Tangaro, Marco-Antonio; Tarhini, Mohamad; Tariq, Mohammad; Tarzila, Madalina-Gabriela; Tauro, Arturo; Tejeda Munoz, Guillermo; Telesca, Adriana; Terasaki, Kohei; Terrevoli, Cristina; Teyssier, Boris; Thaeder, Jochen Mathias; Thomas, Deepa; Tieulent, Raphael Noel; Timmins, Anthony Robert; Toia, Alberica; Trogolo, Stefano; Trombetta, Giuseppe; Trubnikov, Victor; Trzaska, Wladyslaw Henryk; Tsuji, Tomoya; Tumkin, Alexandr; Turrisi, Rosario; Tveter, Trine Spedstad; Ullaland, Kjetil; Uras, Antonio; Usai, Gianluca; Utrobicic, Antonija; Vajzer, Michal; Vala, Martin; Valencia Palomo, Lizardo; Vallero, Sara; Van Der Maarel, Jasper; Van Hoorne, Jacobus Willem; Van Leeuwen, Marco; Vanat, Tomas; Vande Vyvre, Pierre; Varga, Dezso; Diozcora Vargas Trevino, Aurora; Vargyas, Marton; Varma, Raghava; Vasileiou, Maria; Vasiliev, Andrey; Vauthier, Astrid; Vechernin, Vladimir; Veen, Annelies Marianne; Veldhoen, Misha; Velure, Arild; Venaruzzo, Massimo; Vercellin, Ermanno; Vergara Limon, Sergio; Vernet, Renaud; Verweij, Marta; Vickovic, Linda; Viesti, Giuseppe; Viinikainen, Jussi Samuli; Vilakazi, Zabulon; Villalobos Baillie, Orlando; Villatoro Tello, Abraham; Vinogradov, Alexander; Vinogradov, Leonid; Vinogradov, Yury; Virgili, Tiziano; Vislavicius, Vytautas; Viyogi, Yogendra; Vodopyanov, Alexander; Volkl, Martin Andreas; Voloshin, Kirill; Voloshin, Sergey; Volpe, Giacomo; Von Haller, Barthelemy; Vorobyev, Ivan; Vranic, Danilo; Vrlakova, Janka; Vulpescu, Bogdan; Vyushin, Alexey; Wagner, Boris; Wagner, Jan; Wang, Hongkai; Wang, Mengliang; Watanabe, Daisuke; Watanabe, Yosuke; Weber, Michael; Weber, Steffen Georg; Weiser, Dennis Franz; Wessels, Johannes Peter; Westerhoff, Uwe; Whitehead, Andile Mothegi; Wiechula, Jens; Wikne, Jon; Wilde, Martin Rudolf; Wilk, Grzegorz Andrzej; Wilkinson, Jeremy John; Williams, Crispin; Windelband, Bernd Stefan; Winn, Michael Andreas; Yaldo, Chris G; Yang, Hongyan; Yang, Ping; Yano, Satoshi; Yasar, Cigdem; Yin, Zhongbao; Yokoyama, Hiroki; Yoo, In-Kwon; Yoon, Jin Hee; Yurchenko, Volodymyr; Yushmanov, Igor; Zaborowska, Anna; Zaccolo, Valentina; Zaman, Ali; Zampolli, Chiara; Correia Zanoli, Henrique Jose; Zaporozhets, Sergey; Zardoshti, Nima; Zarochentsev, Andrey; Zavada, Petr; Zavyalov, Nikolay; Zbroszczyk, Hanna Paulina; Zgura, Sorin Ion; Zhalov, Mikhail; Zhang, Haitao; Zhang, Xiaoming; Zhang, Yonghong; Chunhui, Zhang; Zhang, Zuman; Zhao, Chengxin; Zhigareva, Natalia; Zhou, Daicui; Zhou, You; Zhou, Zhuo; Zhu, Hongsheng; Zhu, Jianhui; Zichichi, Antonino; Zimmermann, Alice; Zimmermann, Markus Bernhard; Zinovjev, Gennady; Zyzak, Maksym

2016-03-14

The production of prompt D$^+_s$ mesons was measured for the first time in collisions of heavy nuclei with the ALICE detector at the LHC. The analysis was performed on a data sample of Pb–Pb collisions at a centre-of-mass energy per nucleon–nucleon collision of $\\sqrt{s_{\\rm NN}} = 2.76$ TeV in two different centrality classes, namely 0–10\\% and 20–50\\%. D$^+_s$ mesons and their antiparticles were reconstructed at mid-rapidity from their hadronic decay channel D$^+_s \\rightarrow \\phi\\pi^+$, with $\\phi\\rightarrow {\\rm K}^−{\\rm K}^+$, in the transverse momentum intervals $4 < p_{\\rm T} < 12$ GeV/$c$ and $6 < p_{\\rm T} < 12$ GeV/c for the 0–10\\% and 20–50\\% centrality classes, respectively. The nuclear modification factor $R_{\\rm AA}$ was computed by comparing the $p_{\\rm T}$-differential production yields in Pb–Pb collisions to those in proton–proton (pp) collisions at the same energy. This pp reference was obtained using the cross section measured at $\\sqrt{s} = 7$ TeV and scaled ...

U.S. nuclear non-proliferation policy: impact on exports and nuclear industry could not be determined. Report to the Congress

International Nuclear Information System (INIS)

1980-01-01

The Nuclear Non-Proliferation Act of 1978 established new measures to prevent the diversion to weapons use of peaceful nuclear exports. It also created a policy to confirm U.S. reliability as a nuclear supplier. GAO did not identify any export sales lost as a result of the Act, but did find indications that nonproliferation policies can influence export sales. Based on available data, GAO could not determine the impact of the Act on the competitiveness of U.S. nuclear exports. However, U.S. companies are at some disadvantage because importers perceive that implementation of the Act may result in delayed export licenses. The United States dominated the nuclear export market through the early 1970s. However, foreign competitors, some aided by U.S. technology transfers, emerged to monopolize home markets and compete for third-country business. Further, the market has been depressed since 1974 and prospects for U.S. nuclear power plant exports have dimmed greatly. However, U.S. companies continue to view exports as important to sustain production capacity

Determination of Opiinae parasitoids (Hymenoptera: Braconidae) associated with crop infesting Bactrocera spp. (Diptera: Tephritidae) using COI and Cyt b sequences

Science.gov (United States)

Shariff, Safiah; Yaakop, Salmah; Zain, Badrul Munir Md.

2013-11-01

Members of the Opiinae subfamily (Hymenoptera: Braconidae) are well known as important parasitoids of fruit fly larvae (Diptera: Tephritidae). They are widely used as biological control agents of fruit flies, especially the Bactrocera Macquart species that infest fruits. In this study, the larvae of fruit flies were collected from infested crops including star fruit, guava, wax apple and ridge gourd. The parasitized larvae were then reared under laboratory conditions until emergence of the adult parasitoids. Additionally, Malaise trap also was used to collect parasitoid species. The general concept of the multiplex PCR has been performed is to amplify two mitochondrial DNA markers, namely cytochrome oxidase subunit I (COI) and cytochrome b (Cyt b) simultaneously. Therefore, the lengthy process of reaction will be reduced. The status of the fruit fly species has also been confirmed by using COI marker on the early stage of the larvae. Maximum parsimony (MP) and Bayesian Inference (BI) were implemented to help and support the identification of Opiinae species. The result obtained from this study showed three parasitoid genera of the Opiinae viz. Fopius Wharton, Psyttalia Walker and Diachasmimorpha Viereck. Each genus has been determined by clustering together in a similar clade according to their infested crops. Therefore, accurate determination of parasitoids and the fruit fries species was highly useful and necessary for successful biological control of Bactrocera species.

Analysis of Survey Results of the Public's Perceptions of Nuclear Energy

Energy Technology Data Exchange (ETDEWEB)

Kim, Dongwon [Korea Nuclear Energy Foundation, Seoul (Korea, Republic of)

2008-04-15

In the 1970s when the two oil shocks occurred, nuclear energy was recognized as an economic and reliable source of electricity, and the nuclear power industry smoothly developed without much difficulty in the selection of reactor sites, etc. Amid such favorable circumstances, the government and nuclear energy companies gave short shrift to ensuring the public's correct understanding of nuclear energy. The perception of nuclear energy began to deteriorate in the latter half of the 1980s. With the accident at the Three Mile Island nuclear reactor no. 2 in the U. S. in 1979 and the melt-down of Chernobyl nuclear power came to the fore. In addition, the changes in the political and social environment wrought by the democratization movement made the continued development of the nuclear energy industry very difficult. The government had no choice but to seek peoples due to a number of factors including the emergence of a new social atmosphere in which individual freedom and human rights were emphasized over material abundance; increased opposition to nuclear energy by environmental groups that appeared during the course of democratization; antipathy against the previous authoritarian governments; and the people's increased demands for the right to know, etc. The nuclear energy industry also could not conduct its business, including the securing of sites for power plants and nuclear waste, without the people's concurrence.

Status of U.S. nuclear waste disposal programs

International Nuclear Information System (INIS)

Eastering, J.B.

1987-01-01

Since the days of the Manhattan Project in the early 1940's, the United States has recognized the need for a system of effective nuclear waste management. The evolution of that system has been directed by a series of legislative actions to determine responsibilities and develop procedures. Under these laws, the U.S. Department of Energy (DOE), as the lead agency, is required to plan and implement the programs that will ensure safe and efficient management of nuclear wastes from both civilian and defense activities. This overview paper describes the organization of these programs

The new U.S.-ROK civil nuclear cooperation agreement

International Nuclear Information System (INIS)

Tazaki, Makiko; Shimizu, Ryo; Suda, Kazunori

2016-10-01

From March 2010, the U.S. and the Republic of Korea (ROK) started a negotiation for revising “Agreement for Cooperation between the Government of the United States of America and the Government of the Republic of Korea Concerning Civil Uses of Atomic Energy” which had entered into force in March 1973. A top priority of their negotiation was whether or not the U.S. grants its advanced consent to the ROK’s engagement in uranium enrichment (less than 20%) and reprocessing (pyroprocessing) of U.S.-origin nuclear material and spent fuel, despite the U.S.’s nonproliferation policy of preventing emergence of new non-nuclear-weapon states with such sensitive capabilities. Under the “Agreement for Cooperation Between the Government of the United States of America and the Government of the Republic of Korea Concerning Peaceful Uses of Nuclear Energy” (“the new agreement”) which entered into force in November 2015, the ROK has been granted to engage in domestic uranium enrichment and reprocessing activities at certain facilities prescribed in Annexes III and II to the Agreed Minute of the new agreement. As of the date of validation of the agreement, however, no facility names have been appeared in both Annexes. Therefore, as a matter of practice, the ROK has not yet been able to engage in those activities, although the new agreement creates options for the future. Such result has not necessarily and directly reflected both states’ intention of the advanced consent, but considering various facts including that 1) ROK’s domestic uranium enrichment and reprocessing capabilities are neither only nor urgent requisites for ROK’s civil nuclear activities, 2) ROK’s acquisition of such sensitive capabilities could further encourage DPRK’s provocative nuclear activities, and 3) the U.S. and the ROK have been in the process of conducting “Joint Fuel Cycle Study”, in order to pursue technical and economic feasibilities as well as nonproliferation

S-matrix theory of nuclear forces

International Nuclear Information System (INIS)

Vinh Mau, R.

1984-09-01

The use of the S-matrix theory for deriving the nucleon-nucleon interaction is reviewed. Fits to recent NN data are described. Applications to nuclear structure properties and nucleon-nucleus reactions are also discussed, and the results compared with data. 20 references

Atom Mirny: The World’S First Civilian Nuclear Power Plant

International Nuclear Information System (INIS)

Kaiser, Peter; Madsen, Michael

2013-01-01

The world’s first civilian nuclear power plant was commissioned on June 27, 1954 in Obninsk, which was at that time in the Soviet Union, today, the Russian Federation. The Obninsk nuclear power plant generated electricity and supported experimental nuclear research. The Obninsk nuclear power plant operated without incident for 48 years. In September 2002, the last fuel subassembly was unloaded, when the Obninsk nuclear power plant set another first: it became the first nuclear power plant to be decommissioned in Russia

Use of a mitochondrial COI sequence to identify species of the subtribe Aphidina (Hemiptera, Aphididae

Directory of Open Access Journals (Sweden)

Jianfeng WANG

2011-08-01

Full Text Available Aphids of the subtribe Aphidina are found mainly in the North Temperate Zone. The relative lack of diagnostic morphological characteristics has obscured the identification of species in this group. However, DNA-based taxonomic methods can clarify species relationships within this group. Sequence variation in a partial segment of the mitochondrial COI gene was highly effective for resolving species relationships within Aphidina. Forty-five species were correctly identified in a neighbor-joining tree. Mean intraspecific sequence divergence was 0.17%, with a range of 0.00% to 1.54%. Mean interspecific divergence within previously recognized genera or morphologically similar species groups was 4.54%, with variation mainly in the range of 3.50% to 8.00%. Possible reasons for anomalous levels of mean nucleotide divergence within or between some taxa are discussed.

Cryptic variation in an ecological indicator organism: mitochondrial and nuclear DNA sequence data confirm distinct lineages of Baetis harrisoni Barnard (Ephemeroptera: Baetidae in southern Africa

Directory of Open Access Journals (Sweden)

Pereira-da-Conceicoa Lyndall L

2012-02-01

Full Text Available Abstract Background Baetis harrisoni Barnard is a mayfly frequently encountered in river studies across Africa, but the external morphological features used for identifying nymphs have been observed to vary subtly between different geographic locations. It has been associated with a wide range of ecological conditions, including pH extremes of pH 2.9–10.0 in polluted waters. We present a molecular study of the genetic variation within B. harrisoni across 21 rivers in its distribution range in southern Africa. Results Four gene regions were examined, two mitochondrial (cytochrome c oxidase subunit I [COI] and small subunit ribosomal 16S rDNA [16S] and two nuclear (elongation factor 1 alpha [EF1α] and phosphoenolpyruvate carboxykinase [PEPCK]. Bayesian and parsimony approaches to phylogeny reconstruction resulted in five well-supported major lineages, which were confirmed using a general mixed Yule-coalescent (GMYC model. Results from the EF1α gene were significantly incongruent with both mitochondrial and nuclear (PEPCK results, possibly due to incomplete lineage sorting of the EF1α gene. Mean between-clade distance estimated using the COI and PEPCK data was found to be an order of magnitude greater than the within-clade distance and comparable to that previously reported for other recognised Baetis species. Analysis of the Isolation by Distance (IBD between all samples showed a small but significant effect of IBD. Within each lineage the contribution of IBD was minimal. Tentative dating analyses using an uncorrelated log-normal relaxed clock and two published estimates of COI mutation rates suggest that diversification within the group occurred throughout the Pliocene and mid-Miocene (~2.4–11.5 mya. Conclusions The distinct lineages of B. harrisoni correspond to categorical environmental variation, with two lineages comprising samples from streams that flow through acidic Table Mountain Sandstone and three lineages with samples from

Nuclear data newsletter. No. 12

International Nuclear Information System (INIS)

1989-04-01

This issue announces nuclear data libraries received by the IAEA Nuclear Data Section: BROND; JENDL-2 fission product libraries; thermal neutron capture gamma-rays for prompt gamma spectroscopy; ECPL-86; and ENDF/B data processing codes. Data indexes and bibliographies (CINDA-89) are included. A list of a selection of new relevant documents is included

Concordance négative optionnelle : contrastes forts et faibles entre picard et québécois

Directory of Open Access Journals (Sweden)

Dagnac Anne

2016-01-01

Full Text Available Cet article, basédeux études decorpus,comparele phénomène de la concordance négative(CNenpicard et enfrançais montréalais. Après avoir défini les phénomènes étudiés, il présenterapidement lefonctionnement de la négation et de la concordance négative en picard, et leurressemblances avec le système montréalais.La concordance entre marqueur négatifet mot-N y est à la fois possible et optionnelle: j’n’in sais (mie rien ‘je n’en sais rien’ (picard, j’ai (pasrien contre la loi cent un ‘je n’ai rien contre la loi cent un’ (québécois. Les contrastes en termes de contextes syntaxiques permettant ou non la CNoptionnelle, conduisent à poser ces deux dialectes commetypologiquement distinctssur des points considérés comme théoriquement cruciaux, comme la possibilité de la CNentre un marqueur denégation et un mot-N préverbalou dans des énoncés fragmentaires. Néanmoins, onmontre qu’une prise en compte plus fine des propriétéslexicalesdes items en jeuet de leurs fréquences d’emploi relativesmodifiece schéma typologique:elle montred’étonnantes convergences entre les deux systèmes, qui invitent à repenser la manière d’aborder la microvariation syntaxique. L’article défend enfin l’hypothèse que les différences entre les deux dialectes reposent sur l’existence d’un marqueur secondaire en picard, occupant une position syntaxique distinctedu marqueur pas ou point.

Global Zero and Deterrence Credibility : A Critical Analysis of Obama`s Nuclear Policy and Extended Nuclear Deterrence Credibility on the Korean Peninsula

OpenAIRE

Ganss, Mathias

2012-01-01

This thesis is a qualitative case study analysis of the whether the nuclear policies of President Obama has weakened the U.S. extended nuclear deterrence credibility on the Korean Peninsula. To answer this, the thesis employs two strategies: First, two variables are discussed; a nuclear capabilities-variable; and a nuclear policy-variable. The purpose is to assess the impact the New START treaty has on U.S. nuclear capabilities, and to assess the implications of Obama`s nuclear policy, expres...

Purification and partial characterization of canine S100A12.

Science.gov (United States)

Heilmann, Romy M; Suchodolski, Jan S; Steiner, Jörg M

2010-12-01

Canine S100A12 (cS100A12) is a calcium-binding protein of the S100 superfamily of EF-hand proteins, and its expression is restricted to neutrophils and monocytes. Interaction of S100A12 with the receptor for advanced glycation end products (RAGE) has been suggested to play a central role in inflammation. Moreover, S100A12 has been shown to represent a sensitive and specific marker for gastrointestinal inflammation in humans. Only human, porcine, bovine, and rabbit S100A12 have been purified to date, and an immunoassay for the quantification of S100A12 is available only for humans. Therefore, the aim of this study was to develop a protocol for the purification of S100A12 and to partially characterize this protein in the dog (Canis lupus familiaris) as a prelude to the development of an immunologic method for its detection and quantification in canine serum and fecal specimens. Leukocytes were isolated from canine whole blood by dextran sedimentation, and canine S100A12 was extracted from the cytosol fraction of these cells. Further purification of cS100A12 comprised of ammonium sulfate precipitation, hydrophobic interaction chromatography, and strong cation- and anion-exchange column chromatography. Canine S100A12 was successfully purified from canine whole blood. The relative molecular mass of the protein was estimated at 10,379.5 and isoelectric focusing revealed an isoelectric point of 6.0. The approximate specific absorbance of cS100A12 at 280 nm was determined to be 1.78 for a 1 mg/ml solution. The N-terminal AA sequence of the first 15 residues of cS100A12 was Thr-Lys-Leu-Glu-Asp-His-X-Glu-Gly-Ile-Val-Asp-Val-Phe-His, and revealed 100% identity with the predicted protein sequence available through the canine genome project. Sequence homology for the 14 N-terminal residues identified for cS100A12 with those of feline, bovine, porcine, and human S100A12 was 78.6%. We conclude that canine S100A12 can be successfully purified from canine whole blood using the

78 FR 44165 - Nuclear Regulatory Commission Enforcement Policy

Science.gov (United States)

2013-07-23

... NUCLEAR REGULATORY COMMISSION [NRC-2013-0159] Nuclear Regulatory Commission Enforcement Policy AGENCY: Nuclear Regulatory Commission. ACTION: Enforcement policy; request for comment. SUMMARY: The U.S... Policy. In SRM-SECY-12-0047, ``Revisions to the Nuclear Regulatory Commission Enforcement Policy,'' dated...

Prospects for revitalization of the U.S. nuclear energy industry

International Nuclear Information System (INIS)

Colvin, Joe F.

1998-01-01

Today I want to make two key points about the U.S. nuclear energy industry. First, key policy issues are beginning to converge in a way that is very positive for our industry - and for society as a whole. And Second, the industry has worked hard to prepare for the future - and we are ready to make the most of these positive developments. Nuclear energy's prospects are the brightest they have been at any time in history. The plan identifies the building blocks that must be in place before utilities start building the next generation of nuclear plants. One, we wanted to improve the efficiency and reliability of our operating nuclear plants. Two, we wanted to establish a regulatory framework for license renewal. Three, we wanted to develop a more efficient licensing process for new plants. In closing, I am confident that the 21st century will bring a renaissance for nuclear energy-in the United States and around the world. The U.S. nuclear energy industry has a renewed vitality and sense of mission today. We've worked hard preparing for the future- and we will continue to be strong players in worldwide energy policy development in the 21st century. (Cho, G. S.)

De l’effritement à l’androgyne : l’image du couple dans le roman québécois contemporain au féminin De l’effritement à l’androgyne : l’image du couple dans le roman québécois contemporain au féminin

Directory of Open Access Journals (Sweden)

Denisa-Adriana Oprea

2010-05-01

Full Text Available À travers l’analyse d’un corpus de romans québécois contemporains, nous tentons ici de baliser les éléments d’un parcours qui va de l’effritement à l’androgyne. Cette évolution est symptomatique tant de la remise en question du couple qu’engendre le féminisme radical que du passage du féminisme de la deuxième vague au féminisme de la troisième vague. Les romans que nous avons retenus sont Le sexe des étoiles (1987, de Monique Proulx, Copies conformes (1989, de Monique LaRue et la trilogie Soifs de Marie-Claire Blais.À travers l’analyse d’un corpus de romans québécois contemporains, nous tentons ici de baliser les éléments d’un parcours qui va de l’effritement à l’androgyne. Cette évolution est symptomatique tant de la remise en question du couple qu’engendre le féminisme radical que du passage du féminisme de la deuxième vague au féminisme de la troisième vague. Les romans que nous avons retenus sont Le sexe des étoiles1 (1987, de Monique Proulx, Copies conformes2 (1989, de Monique LaRue et la trilogie Soifs3 de Marie-Claire Blais.

Quantifying the Electrocatalytic Turnover of Vitamin B12-Mediated Dehalogenation on Single Soft Nanoparticles.

Science.gov (United States)

Cheng, Wei; Compton, Richard G

2016-02-12

We report the electrocatalytic dehalogenation of trichloroethylene (TCE) by single soft nanoparticles in the form of Vitamin B12 -containing droplets. We quantify the turnover number of the catalytic reaction at the single soft nanoparticle level. The kinetic data shows that the binding of TCE with the electro-reduced vitamin in the Co(I) oxidation state is chemically reversible. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

IAEA Reviews Niger’s Nuclear Power Infrastructure Development

International Nuclear Information System (INIS)

2018-01-01

An International Atomic Energy Agency (IAEA) team of experts has concluded an eight-day mission to Niger to review its infrastructure development for a nuclear power programme. The Integrated Nuclear Infrastructure Review (INIR) was carried out at the invitation of the Government of the Republic of Niger. Niger, whose economic development is hampered by a lack of consistent electricity supply, is considering a potential role for nuclear power in its energy mix. A country of about 21 million people in Western Africa, Niger is currently ranked as the world’s fourth largest producer of uranium ore. The INIR team observed a strong Government commitment to developing the infrastructure for a nuclear power programme. The Government has established a Strategic Orientation Committee for the Nuclear Power Programme chaired by the Prime Minister, and a National Technical Committee for the Nuclear Power Programme chaired by the President of the Nigerien High Authority for Atomic Energy (HANEA). Those two committees form the Nuclear Energy Programme Implementing Organization (NEPIO). Niger has already completed or initiated several studies related to nuclear infrastructure development, and prepared a comprehensive report summarizing the results.

[Genetic structure of Hemibarbus labeo and Hemibarbus medius in South China based on mtDNA COI and ND5 genes].

Science.gov (United States)

Lan, Zhao Jun; Lin, Long Feng; Zhao, Jun

2017-04-18

Both Hemibarbus labeo and H. medius (Cypriniformes: Cyprinidae: Gobioninae) are primary freshwater fishes and are widely distributed. As such, they provide an ideal model for phylogeographical studies. However, the similarity in morphological characters between these two species made the description of their distributions and the validation of species quite challenging. Here we employed variations in the DNA sequences of mitochondrial COI and ND5 genes (2151 bp) to solve this challenge and to study the population genetics structure of these two species. Among the 130 specimens belonging to 8 populations of H. labeo and 9 populations of H. medius from 17 drainage systems in southern China,196 variable sites (9.1% in the full sequences) falling into 50 haplotypes were identified. The haplotype diversity (h) and the nucleotide diversity (π) were 0.964 and 0.019, respectively, indicating a high level of genetic diversity and an evolutionary potential in both species. The result of neighbor-joining tree based on composite nucleotide sequences of the mtDNA COI and ND5 genes showed that the H. labeo and H. medius fell into two major clades (clade1and clade2): clade1was composed of some specimens of Oujiang River, all the specimens of Hanjiang River and Jiulongjiang River, whereas all remaining populations fell in clade2. The genetic distance between clade I and clade II was 0.036, while that between H. labeo and H. medius was 0.027. The haplotype network analyses indicated that the populations of Hanjiang River and Jiulongjiang River had relatively high genetic variation with the rest rivers. The po-pulations of Hainan Island migrated northward to Moyangjaing River. Haplotypes of the rivers of Hainan Island and Moyangjang River had relatively higher genetic variation with the Yangtze River than Pearl River. The populations of Xiangjiang River had no genetic variation with the populations of Guijiang River and Liujiang River. Analysis of molecular variance (AMOVA

Lifetimes of #betta#'s and μ's and short-distance nuclear phenomena

International Nuclear Information System (INIS)

Kisslinger, L.S.

1982-06-01

It is shown that short distance phenomena and thus quark structure play vital roles in the theory of #betta# and μ decays in nuclei. A hybrid two-baryon-quark shell model is used to estimate the lifetimes for nonmesonic decays of #betta#'s and μ's in nuclear matter

Human Resources Development for Jordan’s Nuclear Energy Programme

International Nuclear Information System (INIS)

Malkawi, Salaheddin; Amawi, Dala’

2014-01-01

Jordan's HRD strategy: • Utilize Jordan’s academic infrastructure: – 25 Universities (10 public & 15 private); – 35 Community Colleges (15 public & 20 private). • Build on existing programmes and establish new ones to support Nuclear Energy Programme. • Nuclear Education in Jordan: – B. Sc. Nuclear Engineering at Jordan University of Science & Technology (JUST); – M. Sc. Nuclear Physics at University of Jordan, Yarmouk University and Al-Balqa Applied University. • Scholarships for M. Sc. and Ph. D in Nuclear Engineering and Nuclear Science from Universities outside Jordan: – United States, Russia, France, Japan, China, Korea. Utilization of JSA and JRTR; • Vendor supplied training; • Support through Nuclear Cooperation Agreements; • IAEA Technical Cooperation; • Development of a Jordan-Specific Qualification and Certification Programmes; • Specialized Training in International Codes & Standards: – Transition to JNRC Developed/Adopted Standards, Codes, Regulations

Statistical analysis of nuclear material weighing systems at the Oak Ridge - Y-12 plant

International Nuclear Information System (INIS)

Hammer, A.H.

1980-04-01

The variation in weight measurements on the electronic scales purchased for the Dynamic Special Nuclear Materials Control and Accountability System (DYMCAS) has been characterized and estimated to be more than is acceptable when using the current weighing methods. New weighing procedures have been developed which substantially reduce this variation and bring the weight errors within the Y-12 Plant Nuclear Materials Control and Accountability Department's desired +- 2-g accuracy

Phylogeography and population diversity of Simulium hirtipupa Lutz (Diptera: Simuliidae based on mitochondrial COI sequences.

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Vanderly Andrade-Souza

Full Text Available High morphological homogeneity and cryptic speciation may cause the diversity within Simuliidae to be underestimated. Recent molecular studies on population genetics and phylogeography have contributed to reveal which factors influenced the diversity within this group. This study aimed at examining the genetic diversity of Simulium hirtipupa Lutz, 1910 in populations from the biomes Caatinga, Cerrado, and Atlantic Forest. In this study, we carried out phylogeographic and population genetic analyses using a fragment of the mitochondrial gene COI. The 19 populations studied were clustered into seven groups, most of which are associated with geography indicating certain genetic structure. The northern region of the state of Minas Gerais is most likely the center of origin of this species. The average intergroup genetic distance was 3.7%, indicating the presence of cryptic species. The species tree as well as the haplotype network recovered all groups forming two major groups: the first comprises groups Gr-Bahia (in which the São Francisco river has not acted as geographical barrier, Gr-Pernambuco, and Gr-Mato Grosso do Sul. The second included groups comprising populations of the states of Goiás, Tocantins, Minas Gerais, Bahia, São Paulo, and Espírito Santo. The mismatch distribution for groups was consistent with the model of demographic expansion, except for the Gr-Central-East_1 group. The diversification in this group occurred about 1.19 Mya during the Pleistocene, influenced by paleoclimatic oscillations during the Quaternary glacial cycles.

Measurement of Fragment Production Cross Sections in the $^{12}$C+$^{12}$C and $^{12}$C+$^{197}$Au Reactions at 62 $A$ MeV for Hadrontherapy and Space Radiation Protection

CERN Document Server

Tropea, S; Agodi, C; Blancato, A A; Bondì, M; Cappuzzello, F; Carbone, D; Cavallaro, M; Cirrone, G A P; Cuttone, G; Giacoppo, F; Nicolosi, D; Pandola, L; Raciti, G; Rapisarda, E; Romano, F; Sardina, D; Scuderi, V; Sfienti, C

2014-01-01

Over the last twenty years, there has been a renewed interest in nuclear fragmentation studies for both hadrontherapy applications and space radiation protection. In both fields, fragmentation cross sections are needed to predict the effects of the ions nuclear interactions within the patient’s and the astronaut’s body. Indeed, the Monte Carlo codes used in planning tumor treatments and space missions must be tuned and validated by experimental data. However, only a limited set of fragmentation cross sections are available in literature, especially at Fermi energies. Therefore, we have studied the production of secondary fragments in the 12 C+ 12 C and 12 C+ 197 Au reactions at 62 A MeV. In this work, the measured 4 He cross sections angular distributions at four selected angles are presented and compared.

Nuclear Coexistence: Rethinking U.S. Policy to Promote Stability in an Era of Proliferation

Science.gov (United States)

1994-04-01

into the effects of Israel’s nuclear weapons on regional stability. 25. See David Albright and Mark Hibbs, "Iraq’s Bomb: Blueprints and Artifacts...Foreign Minister Andrei V. Kozyrev warned Ukraine that the possession of deteriorating nuclear warheads could lead to an accident.32 Sovereign Control and...longstanding political disputes. By the standard of nuclear bipolarity, the nuclear politics on the subcontinent are largely a mirror of the U.S.-Soviet nuclear

The Effect of Pleistocene Climate Fluctuations on Distribution of European Abalone (Haliotis tuberculata), Revealed by Combined Mitochondrial and Nuclear Marker Analyses.

Science.gov (United States)

Roussel, Valérie; Van Wormhoudt, Alain

2017-04-01

The genetic differentiation among the populations of the European abalone Haliotis tuberculata was investigated using different markers to better understand the evolutionary history and exchanges between populations. Three markers were used: mitochondrial cytochrome oxidase I (COI), the sperm lysin nuclear gene, and eight nuclear microsatellites. These markers present different characteristics concerning mutation rate and inheritance, which provided complementary information about abalone history and gene diversity. Genetic diversity and relationships among subspecies were calculated from a sample of approximately 500 individuals, collected from 17 different locations in the north-eastern Atlantic Ocean, Macaronesia, and Mediterranean Sea. COI marker was used to explore the phylogeny of the species with a network analysis and two phylogenetic methods. The analysis revealed 18 major haplotypes grouped into two distinct clades with a pairwise sequence divergence up to 3.5 %. These clades do not correspond to subspecies but revealed many contacts along Atlantic coast during the Pleistocene interglaciations. The sperm lysin gene analysis separated two different subtaxa: one associated to Macaronesian islands, and the other to all other populations. Moreover, a small population of the northern subtaxon was isolated in the Adriatic Sea-probably before the separation of the two lineages-and evolved independently. Microsatellites were analyzed by different genetics methods, including the Bayesian clustering method and migration patterns analysis. It revealed genetically distinct microsatellite patterns among populations from Mediterranean Sea, Brittany and Normandy, Morocco, and Canary and Balearic islands. Gene flow is asymmetric among the regions; the Azores and the Canary Islands are particularly isolated and have low effective population sizes. Our results support the hypothesis that climate changes since the Pleistocene glaciations have played a major role in the

SEPT12/SPAG4/LAMINB1 complexes are required for maintaining the integrity of the nuclear envelope in postmeiotic male germ cells.

Science.gov (United States)

Yeh, Chung-Hsin; Kuo, Pao-Lin; Wang, Ya-Yun; Wu, Ying-Yu; Chen, Mei-Feng; Lin, Ding-Yen; Lai, Tsung-Hsuan; Chiang, Han-Sun; Lin, Ying-Hung

2015-01-01

Male infertility affects approximately 50% of all infertile couples. The male-related causes of intracytoplasmic sperm injection failure include the absence of sperm, immotile or immature sperm, and sperm with structural defects such as those caused by premature chromosomal condensation and DNA damage. Our previous studies based on a knockout mice model indicated that SEPT12 proteins are critical for the terminal morphological formation of sperm. SEPT12 mutations in men result in teratozospermia and oligozospermia. In addition, the spermatozoa exhibit morphological defects of the head and tail, premature chromosomal condensation, and nuclear damage. However, the molecular functions of SEPT12 during spermatogenesis remain unclear. To determine the molecular functions of SEPT12, we applied a yeast 2-hybrid system to identify SEPT12 interactors. Seven proteins that interact with SEPT12 were identified: SEPT family proteins (SEPT4 and SEPT6), nuclear or nuclear membrane proteins (protamine 2, sperm-associated antigen 4, and NDC1 transmembrane nucleoproine), and sperm-related structural proteins (pericentriolar material 1 and obscurin-like 1). Sperm-associated antigen 4 (SPAG4; also known as SUN4) belongs to the SUN family of proteins and acts as a linker protein between nucleoskeleton and cytoskeleton proteins and localizes in the nuclear membrane. We determined that SEPT12 interacts with SPAG4 in a male germ cell line through coimmunoprecipitation. During human spermiogenesis, SEPT12 is colocalized with SPAG4 near the nuclear periphery in round spermatids and in the centrosome region in elongating spermatids. Furthermore, we observed that SEPT12/SPAG4/LAMINB1 formed complexes and were coexpressed in the nuclear periphery of round spermatids. In addition, mutated SEPT12, which was screened from an infertile man, affected the integration of these nuclear envelope complexes through coimmunoprecipitation. This was the first study that suggested that SEPT proteins link to

SEPT12/SPAG4/LAMINB1 complexes are required for maintaining the integrity of the nuclear envelope in postmeiotic male germ cells.

Directory of Open Access Journals (Sweden)

Chung-Hsin Yeh

Full Text Available Male infertility affects approximately 50% of all infertile couples. The male-related causes of intracytoplasmic sperm injection failure include the absence of sperm, immotile or immature sperm, and sperm with structural defects such as those caused by premature chromosomal condensation and DNA damage. Our previous studies based on a knockout mice model indicated that SEPT12 proteins are critical for the terminal morphological formation of sperm. SEPT12 mutations in men result in teratozospermia and oligozospermia. In addition, the spermatozoa exhibit morphological defects of the head and tail, premature chromosomal condensation, and nuclear damage. However, the molecular functions of SEPT12 during spermatogenesis remain unclear. To determine the molecular functions of SEPT12, we applied a yeast 2-hybrid system to identify SEPT12 interactors. Seven proteins that interact with SEPT12 were identified: SEPT family proteins (SEPT4 and SEPT6, nuclear or nuclear membrane proteins (protamine 2, sperm-associated antigen 4, and NDC1 transmembrane nucleoproine, and sperm-related structural proteins (pericentriolar material 1 and obscurin-like 1. Sperm-associated antigen 4 (SPAG4; also known as SUN4 belongs to the SUN family of proteins and acts as a linker protein between nucleoskeleton and cytoskeleton proteins and localizes in the nuclear membrane. We determined that SEPT12 interacts with SPAG4 in a male germ cell line through coimmunoprecipitation. During human spermiogenesis, SEPT12 is colocalized with SPAG4 near the nuclear periphery in round spermatids and in the centrosome region in elongating spermatids. Furthermore, we observed that SEPT12/SPAG4/LAMINB1 formed complexes and were coexpressed in the nuclear periphery of round spermatids. In addition, mutated SEPT12, which was screened from an infertile man, affected the integration of these nuclear envelope complexes through coimmunoprecipitation. This was the first study that suggested that SEPT

Isotope shift measurements in the 2s(1/2) -> 2p(3/2) transition of Be+ and extraction of the nuclear charge radii for Be-7,Be-10,Be-11

CERN Document Server

Zakova, M; Yordanov, D T; Lochmann, M; Drake, G W F; Yan, Z-C; Neugart, R; Kowalska, M; Blaum, K; Andjelkovic, Z; Kraemer, J; Bissell, M L; Neff, T; Schmidt-Kaler, F; Sanchez, R; Noertershaeuser, W; Geppert, Ch; Tiedemann, D; Zimmermann, C

2010-01-01

We have performed isotope shift measurements in the 2s(1/2) -> 2p(3/2) transition of Be+ ions using advanced collinear laser spectroscopy with two counter-propagating laser beams. Measurements involving a frequency comb for laser stabilization and absolute frequency determination allowed us to determine the isotope shifts with an accuracy of 2 MHz. From the isotope shifts between Be-9 and Be-7,Be-10,Be-11, high-accuracy mass shift calculations and the charge radius of the reference isotope Be-9 we determined nuclear charge radii for the isotopes Be-7,Be-10 and the one-neutron halo nucleus Be-11. The results are compared to nuclear-structure calculations using the fermionic molecular dynamics model which reproduce well the general trend of the radii. Decreasing charge radii from Be-7 to Be-10 are explained by the cluster structure of the nuclei. The increase from Be-10 to Be-11 is mainly caused by the halo neutron by which the Be-10 core moves relative to the center of mass. Polarization of the Be-10 core has ...

Introduction of the U.S. Nuclear Regulatory Commission's Activities to Reflect Lessons Learned from Fukushima Nuclear Accident

Energy Technology Data Exchange (ETDEWEB)

Kim, Jongtae; Hong, Seong-Wan [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Kim, Gun Hong [Kyungwon E-C Co., Seongnam (Korea, Republic of)

2014-10-15

The Charter requires the staff to highlight potential policy issues for the Commission and provide the Commission every 6 months an update on the review work conducted under the Charter. The recent status of NRC's activities and related program to reflect the lesson-learned from the Fukushima Daiichi nuclear power plant's severe accident are introduced in this paper. A wide variety of the U.S. NRC's activities to reflect lessons learned from the Fukushima nuclear accidents was investigated. From the investigation, it was found that most of NRC's activities, based on the Fukushima Near-Term Task Force (NTTF) recommendations, are being implemented in a comprehensive and systematic manner. The NRC staff initially prioritized the NTTF recommendations based on its judgment of the potential and relative safety enhancement which could be realized by each. As a result of the staff's prioritization and assessment process, the NTTF recommendations were prioritized into three tiers (i.e., Tier 1, 2 and 3). Tier 1 recommendations are which the staff determined should be started without unnecessary delay and for which sufficient resource flexibility, including availability of critical skill sets, exists. Tier 2 recommendations are which could not be initiated in the near term due to factors that include the need for further technical assessment and alignment, dependence on Tier 1 issues, or availability of critical skill sets. Tier 3 recommendations are that require further staff study to support a regulatory action, have an associated shorter term action that needs to be completed to inform the longer-term action, are dependent on the availability of critical skill sets, or are dependent on the resolution of NTTF Recommendation 1. Through the implementation of each tier activities, existing layers of defense in depth are expected to be gradually bolstered, and such a regulatory approach is much similar in the other countries. It was also found that

Introduction of the U.S. Nuclear Regulatory Commission's Activities to Reflect Lessons Learned from Fukushima Nuclear Accident

International Nuclear Information System (INIS)

Kim, Jongtae; Hong, Seong-Wan; Kim, Gun Hong

2014-01-01

The Charter requires the staff to highlight potential policy issues for the Commission and provide the Commission every 6 months an update on the review work conducted under the Charter. The recent status of NRC's activities and related program to reflect the lesson-learned from the Fukushima Daiichi nuclear power plant's severe accident are introduced in this paper. A wide variety of the U.S. NRC's activities to reflect lessons learned from the Fukushima nuclear accidents was investigated. From the investigation, it was found that most of NRC's activities, based on the Fukushima Near-Term Task Force (NTTF) recommendations, are being implemented in a comprehensive and systematic manner. The NRC staff initially prioritized the NTTF recommendations based on its judgment of the potential and relative safety enhancement which could be realized by each. As a result of the staff's prioritization and assessment process, the NTTF recommendations were prioritized into three tiers (i.e., Tier 1, 2 and 3). Tier 1 recommendations are which the staff determined should be started without unnecessary delay and for which sufficient resource flexibility, including availability of critical skill sets, exists. Tier 2 recommendations are which could not be initiated in the near term due to factors that include the need for further technical assessment and alignment, dependence on Tier 1 issues, or availability of critical skill sets. Tier 3 recommendations are that require further staff study to support a regulatory action, have an associated shorter term action that needs to be completed to inform the longer-term action, are dependent on the availability of critical skill sets, or are dependent on the resolution of NTTF Recommendation 1. Through the implementation of each tier activities, existing layers of defense in depth are expected to be gradually bolstered, and such a regulatory approach is much similar in the other countries. It was also found that

Nuclear Energy Center Site Survey, 1975. Part II. The U.S. electric power system and the potential role of nuclear energy centers

International Nuclear Information System (INIS)

1976-01-01

Information related to Nuclear Energy Centers (NEC) in the U.S. is presented concerning the U.S. electric power system today; electricity demand history and forecasts; history and forecasts of the electric utility industry; regional notes; the status, history, and forecasts of the nuclear role; power plant siting problems and practices; nuclear facilities siting problems and practices; origin and evolution of the nuclear energy center concept; conceptualized description of nuclear energy centers; potential role of nuclear energy centers; assumptions, criteria, and bases; typical evolution of a nuclear energy center; and the nuclear fuel cycle

Molecular characterization of Fasciola gigantica from Mauritania based on mitochondrial and nuclear ribosomal DNA sequences.

Science.gov (United States)

Amor, Nabil; Farjallah, Sarra; Salem, Mohamed; Lamine, Dia Mamadou; Merella, Paolo; Said, Khaled; Ben Slimane, Badreddine

2011-10-01

Fasciolosis caused by Fasciola hepatica and Fasciola gigantica (Platyhelminthes: Trematoda: Digenea) is considered the most important helminth infection of ruminants in tropical countries, causing considerable socioeconomic problems. From Africa, F. gigantica has been previously characterized from Burkina Faso, Senegal, Kenya, Zambia and Mali, while F. hepatica has been reported from Morocco and Tunisia, and both species have been observed from Ethiopia and Egypt on the basis of morphometric differences, while the use of molecular markers is necessary to distinguish exactly between species. Samples identified morphologically as F. gigantica (n=60) from sheep and cattle from different geographical localities of Mauritania were genetically characterized by sequences of the first (ITS-1), the 5.8S, and second (ITS-2) Internal Transcribed Spacers (ITS) of nuclear ribosomal DNA (rDNA) genes and the mitochondrial Cytochrome c Oxidase I (COI) gene. Comparison of the sequences of the Mauritanian samples with sequences of Fasciola spp. from GenBank confirmed that all samples belong to the species F. gigantica. The nucleotide sequencing of ITS rDNA of F. gigantica showed no nucleotide variation in the ITS-1, 5.8S, and ITS-2 rDNA sequences among all samples examined and those from Burkina Faso, Kenya, Egypt and Iran. The phylogenetic trees based on the ITS-1 and ITS-2 sequences showed a close relationship of the Mauritanian samples with isolates of F. gigantica from different localities of Africa and Asia. The COI genotypes of the Mauritanian specimens of F. gigantica had a high level of diversity, and they belonged to the F. gigantica phylogenically distinguishable clade. The present study is the first molecular characterization of F. gigantica in sheep and cattle from Mauritania, allowing a reliable approach for the genetic differentiation of Fasciola spp. and providing basis for further studies on liver flukes in the African countries. Copyright © 2011 Elsevier Inc. All

U.S. Strategic Nuclear Forces: Background, Developments, and Issues

Science.gov (United States)

2017-02-10

abandon the strategy of nuclear deterrence that has served as a core concept in U.S. national security strategy for more than 60 years. In a speech in......stated that “the continuous at-sea deterrence provided by a robust and modern fleet of nuclear -powered ballistic missile submarines is critical to

Japanese Nuclear Accident and U.S. Response

International Nuclear Information System (INIS)

Douet, Randy

2011-01-01

U.S. Government response to the Fukushima accident: • Multi-agency task force (Nuclear Regulatory Commission, Department of Energy, Department of Defense) supporting Japan recovery efforts; • President Obama directed the NRC to perform a comprehensive review of U.S. reactors; • NRC established agency task force to develop lessons learned from Fukushima Daiichi accident to provide short-term and long-term analysis of the events

Vitamin B12-catalyzed synthesis of some peracetylated alkyl b-D-xylopyranosides

Directory of Open Access Journals (Sweden)

LJILJANA STEVANOVIC

2003-10-01

Full Text Available The vitamin B12-catalyzed glycosylation reaction of brominated b-D-xylose peracetate with alkanols ROH (C1-C8 has been studied. The catalytically active species in this reaction was cob(Ialamin, obtained by chemical reduction of Vitamin B12 with NaBH4 (Co(III to Co(I. The reaction was carried out with 2 mol% of vitamin B12, with respect to xylosyl bromide 1, under argon at room temperature. Under these conditions, peracetylated C1-C8-alkyl b-D-xylopyranosides (3a–3f were obtained in moderate yield (55–70 %. In all cases 3,4-di-O-acetyl-D-xylal (4 was obtained, as the product of reductive elimination of peracetylated xylosyl bromide (15–25 %.

Radiation safety and the resurgence of nuclear power in the U.S

International Nuclear Information System (INIS)

Harrall, Tom P. Jr.

2008-01-01

Today, in the United States, 104 reactors in 31 states produce electricity for one in five homes and businesses. They have achieved record levels of performance, and their safety levels are unmatched in the U.S. industry. They are the largest source of emission-free electricity in the U.S. and are vital in maintaining the stability of the country's electrical grid. This outstanding record of performance of the U.S. commercial nuclear fleet has laid a solid basis for the next generation of nuclear plants. There is growing interest in adding new nuclear capacity in the U.S., with public announcements having been made expressing intentions to prepare applications for up to 33 new nuclear units at 22 sites in the U.S. To date, seven applications have been filed with the U.S. Nuclear Regulatory Commission (NRC) for new nuclear units. Duke Energy is one of the largest electric power companies in the United States. We supply and deliver energy to approximately 4 million U.S. customers. We have approximately 36,000 megawatts of electric generating capacity in the Midwest and the Carolinas, and natural gas distribution services in Ohio and Kentucky. In addition, we have more than 4,000 megawatts of electric generation in Latin America. Duke operates three nuclear stations with a total capacity of just under 7,000 megawatts in North Carolina and South Carolina. These three stations -Catawba, Mc Guire and Oconee- have each received approval from the NRC for extended operations beyond their initial 40-year license term. On December 13, 2007, Duke submitted a construction and operating license (COL) application to the NRC for the William States Lee III Nuclear Station to be built in South Carolina. A partnership between the U.S. nuclear industry, the Nuclear Energy Institute (NEI), the Electric Power Research Institute (EPRI) and the Institute for Nuclear Power Operations (INPO) was formed to influence the regulatory structure, pursue technology improvements and innovations

Some consideration on nuclear power development. Topics aroused by U.S. proposed 'Generation IV Nuclear Power System

International Nuclear Information System (INIS)

Wang Chuanying; Chen Shiqi

2001-01-01

U.S. proposed 'Generation IV Nuclear Power System' concept. Its origin and proposed goals for it are analyzed; goals are compared with requirements of URD. In particular, discussed issues on nuclear fuel cycle and Non-proliferation. A well-considered nuclear power development plan, paying close attention to international trend and considering comprehensively domestic situation, is expected

From Just War to Nuclear Pacifism: The Evolution of U.S. Christian Thinking about War in the Nuclear Age, 1946–1989

Directory of Open Access Journals (Sweden)

Stephen R. Rock

2018-05-01

Full Text Available During the Cold War, two basic schools of thought emerged among U.S. Christian leaders and ethicists concerning the implications of the nuclear revolution for the use of force by the United States. The just war thinkers held that nuclear war could in fact be conducted within the bounds of traditional just war principles, particularly those of discrimination and proportionality. Since nuclear weapons could be used in war, it followed that they could and should be developed and produced for that purpose and for the purpose of deterrence. The nuclear pacifists held that nuclear war could not be conducted within the confines of traditional just war principles. Since by its nature nuclear war could not be moral, there was no reason for the development and production of nuclear weapons, except for the purpose of deterrence. And since nuclear deterrence required one to make threats of nuclear destruction that it would not be moral to carry out, and, moreover, carried unacceptable risks of miscalculation and inadvertent or accidental use of nuclear weapons, deterrence itself could not be justified, except perhaps as a temporary way station on the path to nuclear disarmament. Although the just war thinkers initially held sway, over time they became less dominant. By the middle of the 1980s, the U.S. Catholic Church and most of the largest Mainline Protestant denominations had formally adopted a nuclear pacifist position. This essay chronicles the victory of nuclear pacifism in these churches, explains it as a reaction to the nuclear weapons and doctrine advocated by the just war thinkers, and implemented by the U.S. government and military, as well as other events and trends in American society, and inquires as to whether or not the just war thinkers and nuclear pacifists influenced the course of U.S. policy.

Annual report - Industrias Nucleares do Brasil S A - 1998

International Nuclear Information System (INIS)

1999-01-01

The annual report of 1998 of Industrias Nucleares do Brasil S A - Brazilian company responsible for the industrial activities of the nuclear fuel cycle - introduces the next main topics: mineral resource directory main actions; industrial directory main actions; finance and administration directory main actions; transparency; environment, safety and quality; the company; and financial statements

The future of nuclear power: Looking ahead. Address at the Japan Atomic Industrial Forum, Sendai, 12 April 1999

International Nuclear Information System (INIS)

ElBaradei, M.

1999-01-01

In his address at the Japan Atomic Industrial Forum (Sendai, 12 April 1999), the Director General of the IAEA described the role of the IAEA for nuclear power development, emphasizing the following aspects: nuclear power and the global energy mix, nuclear safety and the importance of public confidence, economic competitiveness and the role of research and development, and the importance of nuclear verification and prevention of illicit trafficking

Progress on resolving the Gonatocerus tuberculifemur complex: neither COI nor ITS2 sequence data alone can discriminate all the species within the complex, whereas, ISSR-PCR DNA fingerprinting can

Science.gov (United States)

We utilized two molecular methods to aid in resolving the Gonatocerus tuberculifemur complex, potential glassy-winged sharpshooter (GWSS) biological control candidate agents from South America. The two methods used were DNA sequencing of both the mitochondrial cytochrome oxidase subunit 1 gene (COI...

Nuclear asset management. Slide notes

International Nuclear Information System (INIS)

Puglia, W.; Bailey, H.; Kubinova, J.

2004-01-01

Nuclear asset management is defined as the process for making resource allocation and risk management decisions at all levels of nuclear generation business to maximize value/profitability for all stakeholders while maintaining plant safety. In the presentation, the NAM concept is explained, financial benefits achieved in US industry over the past 12 years are outlined, Data Systems and Solutions (DS and S) is presented as a joint venture between Rolls-Royce and SAIC, and NAM benefits in nuclear industry from DS and S client experience are demonstrated. (P.A.)

Chapter 12. Nullification of nuclear reactors

International Nuclear Information System (INIS)

Toelgyessy, J.; Harangozo, M.

2000-01-01

This is a chapter of textbook of radioecology for university students. In this chapter authors deal with problems connected with nullification of nuclear reactors. There are tree basic methods of nullification of nuclear reactors: (1) conservation, (2) safe close (wall up, embed in concrete), (3) direct dismantlement and remotion and two combined ways: (1) combination of mothball with subsequent dismantlement and remotion and (2) combination of safe close with subsequent dismantlement and remotion. Activity levels as well as volumes of radioactive wastes connected with decommissioning of nuclear reactors are reviewed

Nuclear regulation in the 1980s - a leadership role

International Nuclear Information System (INIS)

Asselstine, J.K.

1983-01-01

An overview of cooperation between the Nuclear Regulatory Commission (NRC) and the nuclear industry cites the Institute of Nuclear Power Operations (INPO) as a model for other cooperative efforts, both in determining the need for and the appropriateness of regulatory requirements. The author addresses three needs of nuclear regulation that will be significant during the 1980s: to adapt our regulatory program to a changing workload; to address safety issues, and particularly the development of new safety requirements, for nuclear plants; and to modernize and improve the licensing process. Steps to improve licensing procedures could include standardization, the resolution of design issues before the start of construction, redefinition of the hearing process, limitations of later modifications, stable commission decision making authority, and recognition of the commission's authority to consider economic costs in making regulatory decisions

Nuclear regulatory policy concept on safety, security, safeguards and emergency preparedness (3S+EP)

International Nuclear Information System (INIS)

Ilyas, Zurias

2009-01-01

Regulatory Policy is formulated in regulations that stipulate the assurance of workers and public safety and environmental protection. Legislation and regulations on nuclear energy should consider nuclear safety, security and safeguards, as well as nuclear emergency preparedness (3S+EP) and liability for nuclear damage. Specific requirements stipulated in international conventions and agreements should also be taken into account. Regulatory Policy is formulated in regulations that stipulate the assurance of workers and public safety and environmental protection. Legislation and regulations on nuclear energy should consider nuclear safety, security and safeguards, as well as nuclear emergency preparedness (3S+EP) and liability for nuclear damage. Specific requirements stipulated in international conventions and agreements should also be taken into account. By undertaking proper regulatory oversight on Safety, Security and Emergency Preparedness (3S+EP) as an integrated and comprehensive system, safe and secure use of nuclear energy can be assured. Licence requirements and conditions should fulfil regulatory requirements pertaining to 3S+EP for nuclear installation as an integrated system. An effective emergency capacity that can be immediately mobilized is important. The capacity in protecting the personnel before, during and after the disaster should also be planned. Thus, proper emergency preparedness should be supported by adequate resources. The interface between safety, security, safeguards and emergency preparedness has to be set forth in nuclear regulations, such as regulatory requirements; 3S+EP; components, systems and structures of nuclear installations and human resources. Licensing regulations should stipulate, among others, DIQ, installations security system, safety analysis report, emergency preparedness requirements and necessary human resources that meet the 3S+EP requirements.

Changes in Russia's Military and Nuclear Doctrine

Energy Technology Data Exchange (ETDEWEB)

Wolkov, Benjamin M. [Los Alamos National Laboratory; Balatsky, Galya I. [Los Alamos National Laboratory

2012-07-26

In 1993, the Russian Federation set out a new military doctrine that would determine the direction of its armed forces until President Putin set out the next doctrine in 2000. The Russian Federation creating the doctrine was new; the USSR had recently collapsed, Gorbachev - the creator of the predecessor to this doctrine in 1987 - was out of office, and the new Russian military had only been formed in May, 1992.1 The analysis of the 1993 doctrine is as follows: a definition of how doctrine is defined; a short history of Russian military doctrine leading up to the 1993 doctrine (officially the Basic Provisions of the Military Doctrine of the Russian Federation); and finally, what the doctrine established. An overview of the 1993 doctrine is: (1) Russia's 1993 doctrine was a return to older, more aggressive doctrine as a result of stability concerns surrounding the recent collapse of the USSR; (2) Russia turned from Gorbachev's 'defensive defense' in the 1987 doctrine to aggressive defense with the option of preempting or striking back against an aggressor; (3) Russia was deeply concerned about how nationalism would affect the former Soviet Republics, particularly in respect to the ethnic Russians still living abroad; and (4) Nuclear doctrine pledged to not be the first to use nuclear weapons but provided for the potential for escalation from a conventional to a nuclear war. The 2000 doctrine (officially the Russian Federation Military Doctrine) was created in a more stable world than the 1993 doctrine was. The Russian Federation had survived independence and the 'threat of direct military aggression against the Russian Federation and its allies' had diminished. It had secured all of the nuclear weapons from its neighbors Ukraine, Belarus, and Kazakhstan, and had elected a new president, Vladimir Putin, to replace Boris Yeltsin. Yet, even as the doctrine took more defensive tones than the 1993 doctrine, it expanded its nuclear options

U.S.-Russian cooperation in nuclear disarmament and nonproliferation

Science.gov (United States)

Podvig, Pavel

2010-02-01

The United States and Russia, the two largest nuclear powers, have a special obligation to provide leadership in nuclear disarmament and in strengthening the nuclear non-proliferation regime. In the past year the two countries made an effort to restart the arms control process by concluding a new treaty that would bring their legal disarmament obligations in line with the realities of their post-cold war relationships. The process of negotiating deeper nuclear reductions in the new environment turned out to be rather difficult, since the approaches that the countries used in the past are not well suited to dealing with issues like conversion of strategic nuclear delivery systems to conventional missions, tactical nuclear weapons, or dismantlement of nuclear warheads. This presentation considers the recent progress in U.S.-Russian arms control process and outlines the key issues at the negotiations. It also considers prospects for further progress in bilateral nuclear disarmament and issues that will be encountered at later stages of the process. The author argues that success of the arms reductions will depend on whether the United States and Russia will be able to build an institutional framework for cooperation on a range of issues - from traditional arms control to securing nuclear materials and from missile defense to strengthening the international nuclear safeguards. )

Canada's regulatory framework: The Canadian Nuclear Safety Commission's regulatory framework

International Nuclear Information System (INIS)

Howard, D.

2011-01-01

This paper will discuss the Canadian Nuclear Safety Commission and Canada's Regulatory Framework with respect to Low- and Intermediate-Level Radioactive Waste. The management of low and intermediate level radioactive waste must be ensured in a consistent, environmentally responsible and economical manner throughout its lifecycle -- from its production to the final disposal option. Radioactive waste has been produced in Canada since the early 1930s when the first radium/uranium mine began operating at Port Radium in the Northwest Territories. Pitchblende ore was transported from the Port Radium mine to Port Hope, Ontario where it was refined to produce radium for medical purposes. At present, radioactive waste is generated in Canada from the various stages and uses associated with the nuclear fuel cycle from uranium mining/milling to nuclear reactor operations to radioisotope manufacture and use. The Canadian Nuclear Safety Commission (CNSC regulates the use of nuclear energy and materials to protect the health, safety and security of Canadians and the environment; and to implement Canada's international commitments on the peaceful use of nuclear energy. The CNSC was established in 2000 under the Nuclear Safety and Control Act and reports to Parliament through the Minister of Natural Resources. The CNSC was created to replace the former Atomic Energy Control Board (AECB), which was founded in 1946. Under the Nuclear Safety and Control Act, CNSC's mandate involves four major areas: regulation of the development, production and use of nuclear energy in Canada to protect health, safety and the environment; regulation of the production, possession, use and transport of nuclear substances, and the production, possession and use of prescribed equipment and prescribed information; implementation of measures respecting international control of the development, production, transport and use of nuclear energy and substances, including measures respecting the

Nuclear Materials Management U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO)

International Nuclear Information System (INIS)

Jesse Schreiber

2008-01-01

In light of the changing Defense Complex mission, the high cost to storing and protecting nuclear materials, and in consideration of scarcity of resources, it is imperative that the U.S. Department of Energy (DOE) owned nuclear materials are managed effectively. The U.S. Department of Energy, National Nuclear Security Administration (NNSA) Strategic Action Plan outlines the strategy for continuing to meet America's nuclear security goals, meeting the overall mission challenges of DOE and NNSA as well as giving focus to local missions. The mission of the NNSA/NSO Nuclear Materials Management (NMM) Program is to ensure that nuclear material inventories are accurately assessed and reported, future material needs are adequately planned, and that existing Nevada Test Site (NTS) inventories are efficiently utilized, staged, or dispositioned. The NNSA/NSO understands that the NTS has unique characteristics to serve and benefit the nation with innovative solutions to the complex problems involving Special Nuclear Materials, hazardous materials, and multi-agency, integrated operations. The NNSA/NSO is defining infrastructure requirements for known future missions, developing footprint consolidation strategic action plans, and continuing in the path of facility modernization and improvements. The NNSA/NSO is striving for the NTS to be acknowledged as an ideal location towards mission expansion and growth. The NTS has the capability of providing isolated, large scale construction and development locations for nuclear power or alternate energy source facilities, expanded nuclear material storage sites, and for new development in 'green' technology

10 CFR Appendix S to Part 50 - Earthquake Engineering Criteria for Nuclear Power Plants

Science.gov (United States)

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Earthquake Engineering Criteria for Nuclear Power Plants S... FACILITIES Pt. 50, App. S Appendix S to Part 50—Earthquake Engineering Criteria for Nuclear Power Plants... nuclear power plant structures, systems, and components important to safety to withstand the effects of...

Advanced Passive Reactors : Leading The U. S. Nuclear Renaissance

International Nuclear Information System (INIS)

Henderson, Ronald R.

1990-01-01

Twenty-one years have passed since Korea Electric Power Corporation and Westinghouse announced plans to build Kori 1. Today, Korea's nuclear program is one of the most successful in the world. The electricity generated from Kori 1 and eight other nuclear plants has helped to spark the remarkable growth and transformation of Korea into a modern industrial power. Westinghouse is proud to have been Korea's partner on six of those plants. It the past is the bast prophet of the future, then you and your countrymen should certainly be excited by your future. Korean industry is poised to continue its steady growth, and that means continued growth for your nuclear industry. Currently, the U. S. nuclear industry is experiencing a similar mood of excitement. In fact, it would be necessary to go almost all the way back to the beginning of the birth of the Korean nuclear industry, in 1969, to find a time when the future of nuclear power in the United States looked as bright as it does today. Part of our excitement stems from the welcome prospect of growth. In recent years, there has not been a market for new nuclear plants in the United States. Utilities either had excess capacity or were building plants they had ordered before 1974. For example, between 1980 and 1989, U. S. utilities completed 46 large nuclear units, but didn't order a single new one in that time. Since 1983, however, strong economic growth in the United States has caused the demand for electric power to grow about twice as fast as utilities had projected. Today, utilities will need to order new busload plants. When they do, utilities won't want technology developed 20 years ago. They'll be looking for plants that can meet the environmental, economic, and safety standards of the 21st century

Critical factors supporting the confidence in U.S. nuclear power industries

International Nuclear Information System (INIS)

Yoshida, Tomoaki

2004-01-01

The risk informed regulation in U.S. is summarized and factors supporting the confidence in U.S. nuclear power industries are thought to be helpful to our country for improving the state of nuclear power industries. In U.S., on the basis of clear Regulatory Guide, an entrepreneur constructs and practices corrective action of nonconformance. A regulatory commission submitted by the nation watches their movements. The movements related to regulatory are opened to the people and they make a thousand preparations for the rule to make correct the insufficient part. These above system get good results in U.S. It is important in Japan that we are not going to get away with anything on the system satisfied above conditions and practice. The risk informed regulation, effectiveness of risk informed regulation supporting conditions, a part of NRC (Nuclear Regulatory Commission) and entrepreneur are described. (S.Y.)

Entrepreneurial proliferation: Russia`s nuclear industry suits the buyers market. Master`s thesis

Energy Technology Data Exchange (ETDEWEB)

Whalen, T.D.; Williams, A.R.

1995-06-01

The Soviet Union collapsed in December 1991, bringing an end to four decades of the Cold War. A system of tight centralized controls has given way to chaotic freedom and un-managed, entrepreneurial capitalism. Of immediate concern to most world leaders has been the control and safety of over 30,000 Soviet nuclear weapons. After 1991, the Soviet, centralized system of management lost one key structural element: a reliable `human factor` for nuclear material control. The Soviet systems for physical security and material control are still in place in the nuclear inheritor states - Russia, Ukraine, Khazakhnstan, and Belarus - but they do not restrain or regulate their nuclear industry. In the chaos created by the Soviet collapse, the nonproliferation regime may not adequately temper the supply of the nuclear materials of the new inheritor states. This could permit organizations or states seeking nuclear weapons easier access to fissile materials. New initiatives such as the United States Cooperative Threat Reduction program, which draws upon U.S. technology and expertise to help the NIS solve these complex problems, are short-tern tactics. At present there are no strategies which address the long-tern root problems caused by the Soviet collapse.This thesis demonstrates the extent of the nuclear control problems in Russia. Specifically, we examine physical security, material control and accounting regulation and enforcement, and criminal actions. It reveals that the current lack of internal controls make access to nuclear materials easier for aspiring nuclear weapons States.

Powering Africa's sustainable development: The potential role of nuclear energy

International Nuclear Information System (INIS)

Kessides, Ioannis N.

2014-01-01

The electricity deficit is one of the most serious contemporary issues facing sub-Saharan Africa. Many countries in the region have insufficient generation capacity to meet rapidly rising demand. Electricity shortages have become a binding and powerful constraint on the continent's sustainable development. Their resolution will require coordinated effort to improve the effectiveness and governance of the region's utilities and to significantly scale-up generation capacity. A broad portfolio of low carbon (low-C) technologies needs to be deployed in order to address the electricity deficit in a cost-effective way and not be disruptive to economic growth. Since nuclear power can deliver low-C electricity in bulk, reliably and without intermittency, it could make a significant contribution towards resolving Africa's power crisis. However, the post-Fukushima safety concerns related to large nuclear plants with substantial radioactive inventories will be especially pronounced in Africa. Moreover, large scale reactors with huge upfront investment requirements are likely to be unsuitable for capital-constrained African countries with small electricity grids. One promising direction for nuclear development in Africa might be to downsize reactors from the gigawatt scale to less-complex smaller units (with substantially smaller radioactive inventory) that are more affordable. - Highlights: • We examine the potential role of nuclear power in Africa. • There is growing African interest in nuclear power. • Nuclear power in Africa will require grid strengthening. • Small modular reactors could enhance Africa's energy security. • There are concerns about Africa's safety culture for nuclear power

U.S. Central Station Nuclear Power Plants: operating history

International Nuclear Information System (INIS)

1976-01-01

The information assembled in this booklet highlights the operating history of U. S. Central Station nuclear power plants through December 31, 1976. The information presented is based on data furnished by the operating electric utilities. The information is presented in the form of statistical tables and computer printouts of major shutdown periods for each nuclear unit. The capacity factor data for each unit is presented both on the basis of its net design electrical rating and its net maximum dependable capacity, as reported by the operating utility to the Nuclear Regulatory Commission

Italian Science Fiction, Nuclear Technologies: Narrative Strategies Between the “Two Cultures” (1950s-1970s)

International Nuclear Information System (INIS)

Iannuzzi, Giulia

2017-01-01

This chapter critically investigates how science fiction interacted with, and contributed to the development of a collective imagery related to nuclear energy in Italy between the 1950s and the 1970s, within a context characterized by a difficult relationship between the “two cultures”. To do this, it takes into account the theme of nuclear technologies in science fiction genre narratives, and its treatment on the part of non-genre Italian writers. An initial enthusiasm toward nuclear energy is interpreted as part of new hopes connected to an unprecedented modernization in the peninsula and a new centrality of techno-science – of which science fiction was an apt expression. The hostility toward both nuclear technologies and science fiction on the part of the Italian cultural elite during subsequent decades is read as two different sides of the same “malaise of modernity”.

Countering Putin’s Nuclear Backed Aggression with a Continuous Nuclear Capable Bomber Presence

Science.gov (United States)

2016-05-13

bribery and propaganda to instigate protesting within the populace and thus destabilize Ukraine. 16 Russia was very careful to legally qualify any...proved again that Putin is willing to use different tactics to secure their buffer zone. Though the aggression into the Ukraine was called “an act of...Credible Nuclear Deterrent.” Air and Space Journal. (Fall, 2010 ). 29 Pifer, Steven. “Obama’s Faltering Nuclear Legacy: The 3 Rs.” The Washington

Leveraging U.S. nuclear weapons policy to advance U.S. nonproliferation goals : implications of major theories of international relations.

Energy Technology Data Exchange (ETDEWEB)

Walter, Andrew

2009-06-01

National policymakers are currently considering a dilemma of critical importance to the continued security of the United States: how can U.S. nuclear weapons policies be leveraged to benefit U.S. nuclear nonproliferation goals in the near-term, without sacrificing U.S. national security? In its role supporting U.S. nuclear weapons policy, Sandia National Laboratories has a responsibility to provide objective technical advice to support policy deliberations on this question. However, to best fulfill this duty Sandia must have a broader understanding of the context of the problem. To help develop this understanding, this paper analyzes the two predominant analytical perspectives of international relations theory to explore their prescriptions for how nuclear weapons and nonproliferation policies interact. As lenses with which to view and make sense of the world, theories of international relations must play a crucial role in framing the trade-offs at the intersection of the nuclear weapons and nonproliferation policy domains. An analysis of what these theories suggest as courses of action to leverage nuclear weapons policies to benefit nonproliferation goals is then offered, with particular emphasis on where the policy prescriptions resulting from the respective theories align to offer near-term policy changes with broad theoretical support. These policy prescriptions are then compared to the 2001 Nuclear Posture Review to understand what the theories indicate policymakers may have gotten right in their dealing with the nuclear dilemma, and where they may have gone wrong. Finally, a brief international relations research agenda is proposed to help address the dilemma between nuclear deterrence and nuclear nonproliferation policies, with particular emphasis on how such an agenda can best support the needs of the policy community and a potential 'all things nuclear' policy deliberation and decision-support framework.

Computers in Nuclear Medicine. Chapter 12

Energy Technology Data Exchange (ETDEWEB)

Parker, J. A. [Division of Nuclear Medicine and Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (United States)

2014-12-15

In 1965, Gordon Moore, a co-founder of Intel, said that new memory chips have twice the capacity of prior chips, and that new chips are released every 18 to 24 months. This statement has become known as Moore’s law. Moore’s law means that memory size increases exponentially. More generally, the exponential growth of computers has applied not only to memory size, but also to many computer capabilities, and since 1965, Moore’s law has remained remarkably accurate. Further, this remarkable growth in capabilities has occurred with a steady decrease in price. Anyone who has even a little appreciation of exponential growth realizes that exponential growth cannot continue indefinitely. However, the history of computers is littered with ‘experts’ who have prematurely declared the end of Moore’s law. The quotation at the beginning of this section indicates that future growth of computers has often been underestimated. The exponential growth of computer capabilities has a very important implication for the management of a nuclear medicine department. The growth in productivity of the staff of a department is slow, especially when compared to the growth in capabilities of a computer. This means that whatever decision was made in the past about the balance between staff and computers is now out of date. A good heuristic is: always apply more computer capacity and less people to a new task. Or stated more simply, hardware is ‘cheap’, at least with respect to what you learned in training or what you decided last time you considered the balance between hardware and ‘peopleware’.

Nuclear Liability Act. RS, c.29 (1st supp.), s.1

International Nuclear Information System (INIS)

1985-01-01

The Revised Statutes of Canada 1985 which entered into force on 12 December 1988 revoked the Nuclear Liability Act of 1970, replacing it with a new version. The new Act (Chapter N-28 of the Revised Statutes) updates the previous text and makes some linguistic corrections. The principles of the Act of 1970 remain unchanged, namely absolute liability of the nuclear operator, such liability being limited in amount and in time [fr

Trend analyses of transformer problems in the U.S. nuclear power plants

International Nuclear Information System (INIS)

Shimada, Yoshio

2009-01-01

Up to 2007, the authors have conducted the trend analyses of trouble events related to main generators, emergency diesel generators, breakers and motors, which are more likely to cause problems than other electric equipments in nuclear power plants. The frequency of trouble events in transformers in domestic nuclear power plants at present is approximately one third of the publicly reported cases in the U.S. However, as the situation of maintenance in Japan in the future will become similar to those in the U.S. if the operating period is extended or the maintenance method is to be shifted from preventive maintenance to condition based maintenance, there is a concern that the frequency of transformer events in Japan will increase in Japan, also. Thus, trend analyses were conducted on transformers events which had not been subject to such analyses, from among electrical equipments which are likely to cause problems. The trend analyses were performed on 23 transformer events which had occurred in the U.S. nuclear power plants in five years from 2003 through 2007 among events reported in the Licensee Event Reports (LERs: event reports submitted to NRC by U.S. nuclear power plants) which have been registered in the nuclear information database of the Institute of Nuclear Safety System, Incorporated's (INSS), as well as 8 events registered in the Nuclear Information Archives (NUCIA), which had occurred in domestic nuclear power plants in five from 2003 through 2007. Lessons learned from the trend analyses of the transformer trouble events in the U.S. revealed that for transformers in general, the maintenance management of tap changers is important, while for the main transformers which are most likely to cause problems, it is vital to prevent the deterioration of insulation and insulating oil. (author)

Sixth-order Douglas-Kroll: two-component reference data for one-electron ions from 1s12 through 4f72

International Nuclear Information System (INIS)

Wuellen, Christoph van

2005-01-01

Quasirelativistic Douglas-Kroll calculations including spin-orbit interaction have been performed for hydrogen-like (one-electron) ions. The Douglas-Kroll operators have been implemented up to the sixth order, and a huge even-tempered basis set has been applied that gives results to microhartree accuracy for the energy levels 1s 12 through 4f 72 for all ions with nuclear charge from Z=1 up to Z=100. Besides providing reference data for other implementations, these results can be used to analyse the performance of the Douglas-Kroll method. Such an analysis is presented for the 1s energy levels and the spin-orbit splitting of the 2p shell. The leading order of the error of the Douglas-Kroll result is different for 2s and 2p 12 although these levels are degenerate both at nonrelativistic and Dirac level

Morphological identification and COI barcodes of adult flies help determine species identities of chironomid larvae (Diptera, Chironomidae).

Science.gov (United States)

Failla, A J; Vasquez, A A; Hudson, P; Fujimoto, M; Ram, J L

2016-02-01

Establishing reliable methods for the identification of benthic chironomid communities is important due to their significant contribution to biomass, ecology and the aquatic food web. Immature larval specimens are more difficult to identify to species level by traditional morphological methods than their fully developed adult counterparts, and few keys are available to identify the larval species. In order to develop molecular criteria to identify species of chironomid larvae, larval and adult chironomids from Western Lake Erie were subjected to both molecular and morphological taxonomic analysis. Mitochondrial cytochrome c oxidase I (COI) barcode sequences of 33 adults that were identified to species level by morphological methods were grouped with COI sequences of 189 larvae in a neighbor-joining taxon-ID tree. Most of these larvae could be identified only to genus level by morphological taxonomy (only 22 of the 189 sequenced larvae could be identified to species level). The taxon-ID tree of larval sequences had 45 operational taxonomic units (OTUs, defined as clusters with >97% identity or individual sequences differing from nearest neighbors by >3%; supported by analysis of all larval pairwise differences), of which seven could be identified to species or 'species group' level by larval morphology. Reference sequences from the GenBank and BOLD databases assigned six larval OTUs with presumptive species level identifications and confirmed one previously assigned species level identification. Sequences from morphologically identified adults in the present study grouped with and further classified the identity of 13 larval OTUs. The use of morphological identification and subsequent DNA barcoding of adult chironomids proved to be beneficial in revealing possible species level identifications of larval specimens. Sequence data from this study also contribute to currently inadequate public databases relevant to the Great Lakes region, while the neighbor

Genetic diversity in two Japanese flounder populations from China seas inferred using microsatellite markers and COI sequences

Science.gov (United States)

Xu, Dongdong; Li, Sanlei; Lou, Bao; Zhang, Yurong; Zhan, Wei; Shi, Huilai

2012-07-01

Japanese flounder is one of the most important commercial species in China; however, information on the genetic background of natural populations in China seas is scarce. The lack of genetic data has hampered fishery management and aquaculture development programs for this species. In the present study, we have analyzed the genetic diversity in natural populations of Japanese flounder sampled from the Yellow Sea (Qingdao population, QD) and East China Sea (Zhoushan population, ZS) using 10 polymorphic microsatellite loci and cytochrome c oxidase subunit I (COI) sequencing data. A total of 68 different alleles were observed over 10 microsatellite loci. The total number of alleles per locus ranged from 2 to 9, and the number of genotypes per locus ranged from 3 to 45. The observed heterozygosity and expected heterozygosity in QD were 0.733 and 0.779, respectively, and in ZS the heterozygosity values were 0.708 and 0.783, respectively. Significant departures from Hardy-Weinberg equilibrium were observed in 7 of the 10 microsatellite loci in each of the two populations. The COI sequencing analysis revealed 25 polymorphic sites and 15 haplotypes in the two populations. The haplotype diversity and nucleotide diversity in the QD population were 0.746±0.072 8 and 0.003 34±0.001 03 respectively, and in ZS population the genetic diversity values were 0.712±0.047 0 and 0.003 18±0.000 49, respectively. The microsatellite data ( F st =0.048 7, P <0.001) and mitochondrial DNA data ( F st =0.128, P <0.001) both revealed significant genetic differentiation between the two populations. The information on the genetic variation and differentiation in Japanese flounder obtained in this study could be used to set up suitable guidelines for the management and conservation of this species, as well as for managing artificial selection programs. In future studies, more geographically diverse stocks should be used to obtain a deeper understanding of the population structure of Japanese

The U.S. program for fusion nuclear technology development

International Nuclear Information System (INIS)

Clarke, J.F.; Haas, G.M.

1989-01-01

The Fusion Nuclear Technology (FNT) research and development program in the United States is shaped by a hierarchy of documents and by the environment for nuclear energy existing in the United States. The fission nuclear industry in the United States has suffered problems with public perception of safety, waste disposal issues, and economics as influenced by safety and environmental issues. For fusion to be a viable energy alternative, it must offer significant improvements in these areas. The hierarchy of documents defining objectives, plans, and strategy of the U.S. FNT program consists of the Magnetic Fusion Program Plan (MFPP) (February 1985), the Technical Planning Activity Final Report (January 1987), the Finesse Program Report (January 1987), and the Blanket Comparison and Selection Study Final Report (September 1984). In addition, two other documents are also significant in shaping FNT policy. These are the IEA report on Material for Fusion (December 1986) and the Summary of the Report of the Senior Committee on Environmental, Safety, and Economic Aspects of Magnetic Fusion Energy (September 1987). The U.S. Magnetic Fusion Program Plan defines four key technical issues (magnetic confinement systems, properties of burning plasmas, fusion nuclear technology, and fusion materials). (orig./KP)

Species Authentication of Common Meat Based on PCR Analysis of the Mitochondrial COI Gene.

Science.gov (United States)

Dai, Zhenyu; Qiao, Jiao; Yang, Siran; Hu, Shen; Zuo, Jingjing; Zhu, Weifeng; Huang, Chunhong

2015-07-01

Adulteration of meat products and costly animal-derived commodities with their inferior/cheaper counterparts is a grievous global problem. Species authentication is still technical challenging, especially to those deep processed products. The present study described the design of seven sets of species-specific primer based on a high heterozygous region of mitochondrial cytochrome c oxidase subunit I (COI) gene. These primers were proven to have high species specificity and no cross-reactions and unexpected products to different DNA source. Multiplex PCR assay was achieved for rapid and economical identification of four commonly consumed meats (pork, beef, chicken, and mutton). The conventional PCR assay was sensitive down to 0.001 ng of DNA template in the reactant. The developed method was also powerful in detecting as low as 0.1-mg adulterated pork (0.05 % in wt/wt) in an artificial counterfeited mutton. Validation test showed that the assay is specific, reproducible, and robust in commercial deep processed meats, leatherware, and feather commodities. This proposed method will be greatly beneficial to the consumers, food industry, leather, and feather commodity manufacture.

Experience gained in enhancing operational safety at ComEd`s nuclear power plants

Energy Technology Data Exchange (ETDEWEB)

Elias, D [Commonwealth Edison Co. (United States)

1997-09-01

The following aspects of experience gained in enhancing operational safety at Comed`s nuclear power plants are discussed: nuclear safety policy; centralization/decentralization; typical nuclear operating organization; safety review boards; human performance enhancement; elements of effective nuclear oversight.

The U.S. nuclear power program : Poised for the 21st century

International Nuclear Information System (INIS)

Goldstein, Carl

1994-01-01

The Nuclear Energy Institute is the latest incarnation of the U.S. nuclear industry's national association structure. It all started, as I said, with the AIF, then began to expand in the mid-1970s with the creation of a separate government-affairs association. The structure really fissioned after the 1979 accident at Three Mile Island. At that time, the industry leaders put in place the Institute of Nuclear Power Operations and an augmented public-information function under AIF, known as the Committee for Energy Awareness. In 1983, that Committee became an independent association and its resources were dramatically increased. The name was changed to the U.S. Committee for Energy Awareness. In 1987, the AIF and the U.S. committee merged to form the U.S. Council for Energy Awareness. And now, we are going to an even more streamlined organization-the Nuclear Energy Institute. It will incorporate the functions of three councils: one handling government affairs, one licensing and regulatory issues and USCEA, the communications arm; plus the nuclear activities of the Edison Electric Institute. Everything else stays in place--for example, INPO, the Electric Power Research Institute and the American Nuclear Society. NEI is being planned to have a broad and diversified international membership-utilities, manufacturers, architect-engineers, fuel-cycle companies, research institutions, trade unions, and non-power producers and users of nuclear energy. Of course, the industry leadership expects every one of the 45 U.S. nuclear reactor licensees to belong to NEI. There are still some details to be worked our regarding membership and dues categories, committee structures and-of special interest to many of you-how overseas organizations will be integrated into the Institute. But clearly we intend to continue a close working relationship with our overseas colleagues. That said, let me take a few minutes and look beyond the association structure, to the way the U.S. industry as a

An Evaluation of North Korea’s Nuclear Test by Belbasi Nuclear Tests Monitoring Center-KOERI

Science.gov (United States)

Necmioglu, O.; Meral Ozel, N.; Semin, K.

2009-12-01

Bogazici University and Kandilli Observatory and Earthquake Research Institute (KOERI) is acting as the Turkish National Data Center (NDC) and responsible for the operation of the International Monitoring System (IMS) Primary Seismic Station (PS-43) under Belbasi Nuclear Tests Monitoring Center for the verification of compliance with the Comprehensive Nuclear-Test-Ban Treaty (CTBT) since February 2000. The NDC is responsible for operating two arrays which are part of the IMS, as well as for transmitting data from these stations to the International Data Centre (IDC) in Vienna. The Belbasi array was established in 1951, as a four-element (Benioff 1051) seismic array as part of the United States Atomic Energy Detection System (USAEDS). Turkish General Staff (TGS) and U.S. Air Force Technical Application Center (AFTAC) under the Defense and Economic Cooperation Agreement (DECA) jointly operated this short period array. The station was upgraded and several seismometers were added to array during 1951 and 1994 and the station code was changed from BSRS (Belbasi Seismic Research Station) to BRTR-PS43 later on. PS-43 is composed of two sub-arrays (Ankara and Keskin): the medium-period array with a ~40 km radius located in Ankara and the short-period array with a ~3 km radius located in Keskin. Each array has a broadband element located at the middle of the circular geometry. Short period instruments are installed at depth 30 meters from the surface while medium and broadband instruments are installed at depth 60 meters from surface. On 25 May 2009, The Democratic People’s Republic of Korea (DPRK) claimed that it had conducted a nuclear test. Corresponding seismic event was recorded by IMS and IDC released first automatic estimation of time (00:54:43 GMT), location (41.2896°N and 129.0480°E) and the magnitude (4.52 mb) of the event in less than two hours time (USGS: 00:54:43 GMT; 41.306°N, 129.029°E; 4.7 mb) During our preliminary analysis of the 25th May 2009 DPRK

Morphological and molecular genetic analysis of Synhimantus (Synhimantus laticeps (Rudolphi, 1819 (Nematoda, Acuariidae from the barn owl (Tyto alba and the common kestrel (Falco tinnunculus in Austria

Directory of Open Access Journals (Sweden)

Ebmer D.

2017-09-01

Full Text Available In the framework of the biodiversity initiative and barcoding project “Austrian Barcode of Life” (ABOL post mortem examinations of the gastro-intestinal tracts of different species of wild birds were carried out and several adult helminths were retrieved. In the gizzard of two barn owls (Tyto alba and one common kestrel (Falco tinnuculus acuariid nematodes belonging to the species Synhimantus (Synhimantus laticeps (Rudolphi, 1819 were discovered. This report illustrates the identification of this parasitic nematode by morphometric comparison and scanning electron microscopic photographs. Furthermore, genetic identification of individual parasites based on a fragment of the mitochondrial cytochrome c oxidase subunit I (COI gene and the nuclear 18S ribosomal RNA gene was carried out. This report constitutes the first COI-based DNA barcoding of S. (S. laticeps and its first record in the barn owl (Tyto alba in Austria.

Cost Probability Analysis of China's Nuclear Fuel Cycle Transition

International Nuclear Information System (INIS)

Gao, R. X.; Ko, W. I.; Lee, S. H.

2015-01-01

The Chinese government has already determined to develop the closed nuclear fuel cycle, its long-term roadmap of spent fuel management has not been decided yet. Currently, it seems that China's booming economy gives abundant financial assurance to develop nuclear programs in full play according to its near-term national plans. However, the viability and sustainability of nuclear power always depends critically on its economics. Therefore, it is necessary to conduct a well focused cost-benefit and objective analysis of China's ongoing nuclear power programs with the future prospects. In this study, we conduct a comparative analysis of electricity generation cost in four reference nuclear fuel cycle transition scenarios by 2050. Direct disposal is assumed to produce the cheapest LCT as low as 62.688 mills/kWh compared to the other options. However, after performing a relative uncertainty study, the results show that the capital cost of reactor is the key cost component which leads to the cost gap

Cost Probability Analysis of China's Nuclear Fuel Cycle Transition

Energy Technology Data Exchange (ETDEWEB)

Gao, R. X. [Univ. of Science and Technology, Daejeon (Korea, Republic of); Ko, W. I.; Lee, S. H. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2015-05-15

The Chinese government has already determined to develop the closed nuclear fuel cycle, its long-term roadmap of spent fuel management has not been decided yet. Currently, it seems that China's booming economy gives abundant financial assurance to develop nuclear programs in full play according to its near-term national plans. However, the viability and sustainability of nuclear power always depends critically on its economics. Therefore, it is necessary to conduct a well focused cost-benefit and objective analysis of China's ongoing nuclear power programs with the future prospects. In this study, we conduct a comparative analysis of electricity generation cost in four reference nuclear fuel cycle transition scenarios by 2050. Direct disposal is assumed to produce the cheapest LCT as low as 62.688 mills/kWh compared to the other options. However, after performing a relative uncertainty study, the results show that the capital cost of reactor is the key cost component which leads to the cost gap.

The role of nuclear power in meeting future U.S. energy needs

International Nuclear Information System (INIS)

Wiggin, E.A.

1977-01-01

Uranium and coal are domestically available fuels that provide a viable means for augmenting dwindling indigenous supplies of natural gas and imported oil to meet U.S. electric power needs during the remainder of the twentieth century. Their availability, coupled with a proven technology for utilizing them efficiently, offers the U.S. an attractive route to energy independence. Uranium, through the breeder, offers the further potential of helping the U.S. meet its energy needs into the twenty-first century - hopefully, until fusion and other high technology alternatives can be brought to commercialization. Notwithstanding the financial, regulatory and institutional problems that have plagued the U.S. nuclear power program over the past two years, the utility industry has maintained its commitment to nuclear power. This reflects to some extent, the absence of a viable alternative. But more importantly, it reflects a conviction on the part of the U.S. utility industry, based on an unmatched record of reliable and safe performance, that nuclear power offers the most economic and most environmentally acceptable means of generating steam to produce electricity. This paper considers the likelihood of the U.S. industry's further commitment to nuclear power vis-a-vis comparable commitments in other parts of the world. It points out wherein those commitments will be contingent upon closing the nuclear fuel cycle. It also addresses, the extent to which such commitments will be influenced by government policy and regulation, financing and manpower requisites, and the challenge of the critics. Finally, this paper points out wherein nuclear power is already a de facto key to a U.S. national energy policy and wherein it can further contribute to the goal of energy independence

Nuclear transmutations

International Nuclear Information System (INIS)

Mikulaj, V.

1992-01-01

Two types of nuclear transmutations are outlined, namely the radioactive transmutations and nuclear reactions. The basic characteristics are given of radioactive transmutations (gamma transmutations and isomeric transitions, beta, alpha transmutations, spontaneous fission and spontaneous emission of nucleons), their kinetics and the influence of the physical and chemical state of the radionuclide on the transmutation rate. The basic characteristics are described of nuclear reactions (reactions of neutrons including fission, reactions induced by charged particles and photons), their kinetics, effective cross sections and their mechanism. Chemical reactions caused by nuclear transmutations are discussed (recoil energy, properties of hot atoms, Szilard-Chalmers effect). A brief information is given on the behavior of radionuclides in trace concentrations. (Z.S.) 2 tabs., 19 figs., 12 refs

New U.S. nuclear export legislation

International Nuclear Information System (INIS)

Patermann, C.

1978-01-01

The new 1978 Export Control Act of the United States of America introduces a comprehensive arrangement of the criteria, responsibilities and procedures associated with nuclear exports, especially under the nonproliferation aspect. After a detailed analysis of the multitude of provisions it must be feared that, merely as a result of the high degree of formalization, bureaucratization and politicalization of these procedures, the U.S. can henceforth no longer be regarded as a reliable source of nuclear materials and facilities. An aspect received abroad with particular anguish is the fact that this unilateral aggravation of export controls was initiated after the start of the two-year INFCE program for international fuel cycle evaluation and that the new legislation forces the American government to renegotiate existing agreements on cooperation with the receiver countries under the threat of a delivery stop. (orig.) [de

COMPARISON OF S-CO2 POWER CYCLES FOR NUCLEAR ENERGY

Directory of Open Access Journals (Sweden)

Ladislav Vesely

2016-12-01

Full Text Available The supercritical carbon dioxide (S-CO2 is a possible cooling system for the new generations of nuclear reactors and fusion reactors. The S-CO2 power cycles have several advantages over other possible coolants such as water and helium. The advantages are the compression work, which is lower than in the case of helium, near the critical point and the S-CO2 is more compact than water and helium. The disadvantage is so called Pinch point which occurs in the regenerative heat exchanger. The pinch point can be eliminated by an arrangement of the cycle or using a mixture of CO2. This paper describes the S-CO2 power cycles for nuclear fission and fusion reactors.

Emissions in potassium vapour under 4S1/2-7S1/2 two-photon nsec excitation

International Nuclear Information System (INIS)

Pentaris, D.; Chatzikyriakos, G.; Armyras, A.; Efthimiopoulos, T.

2010-01-01

The two-photon excitation of 4S 1/2 -7S 1/2 transition of potassium atoms is studied. Several coherent emissions and processes are possible, such as parametric four-wave (PFWM), parametric six-wave (PSWM) mixing and competition with the stimulated hyper Raman (SHRS) and the amplified spontaneous emission (ASE). The radiations at the transitions 6P 3/2,1/2 -4S 1/2 , 6S 1/2 -4P 3/2,1/2 and 5P 3/2,1/2 -4S 1/2 are emitted only in the forward direction (indicating a parametric process), while the radiation at the transition 4P 3/2,1/2 -4S 1/2 is emitted in the forward and in the backward direction, indicating an ASE process.

Study for Action Plan proposal on some issues of the national nuclear infrastructure for the new research reactor project in phase 1&2

International Nuclear Information System (INIS)

Cao Hong Lan; Bui Dang Hanh; Nguyen Nhi Dien

2017-01-01

The Project on construction for a new research reactor in Vietnam is under preparation. At the same time, it is necessary to prepare a firm and comprehensive national nuclear infrastructure which is aimed to implement smoothly and ensure safety and security for the project. How is the status of the nuclear infrastructure for research reactor project in Vietnam, how can it be assessed, what is the assessment used for and what are we going to do with that? So, all of these things are the goals set out to address in this Task. However, due to time constraints and conformity with requirement of project progress, this Task assessed only 8 critical issues in infrastructure in phase 1&2, including National position; Management; Legislative framework; Regulatory framework; Human resource development; Radioactive waste; Site survey, site selection and evaluation; and Environmental protection. Conditions and criteria in the documents on milestones and assessment of the national nuclear infrastructure to support a new research reactor project of the International Atomic Energy Agency (IAEA) were used as bases for assessing the Vietnam's infrastructure status. The results of the Task are assessment and identification for gaps which need to be addressed and proposing for a plan on completing the national nuclear infrastructure for the research reactor project on 8 issues in stages 1&2. (author)

THE NUCLEAR ACTIVITIES OF NEARBY S0 GALAXIES

Energy Technology Data Exchange (ETDEWEB)

Xiao, Meng-Yuan; Gu, Qiu-Sheng; Chen, Yan-Mei; Zhou, Luwenjia, E-mail: qsgu@nju.edu.cn [School of Astronomy and Space Science, Nanjing University, Nanjing 210093, P. R. China (China)

2016-11-01

We present a study of nuclear activities in nearby S0 galaxies. After cross-matching the Sloan Digital Sky Survey Data Release 7 with the Third Reference Catalog of Bright Galaxies (RC3) and visually checking the SDSS images, we derive a sample of 583 S0 galaxies with the central spectrophotometric information. In order to separate nebular emission lines from the underlying stellar contribution, we fit the stellar population model to the SDSS spectra of these S0 galaxies. According to the BPT diagram, we find that 8% of S0 galaxies show central star-forming activity, while the fractions of Seyfert, Composite, and low-ionization nuclear emission-line regions (LINERs) are 2%, 8%, and 21.4%, respectively. We also find that star-forming S0s have the lowest stellar masses, over one magnitude lower than the others, and that the active S0s are mainly located in the sparse environment, while the normal S0s are located in the dense environment, which might suggest that the environment plays an important role in quenching star formation and/or AGN activity in S0 galaxies. By performing bulge-disk decomposition of 45 star-forming S0s in g - and r -bands with the 2D fitting software Galfit, as well as exploiting the catalog of 2D photometric decompositions of Meert et al., we find that the bulges of approximately one-third of star-forming S0 galaxies (16/45) are bluer than their disks, while for other types of S0s the bulge and disk components show similar color distributions. Besides, the Sérsic index of most star-forming S0s bulges is less than two, while for normal S0s, it is between two and six.

Reconstructing the phylogeny of Scolytinae and close allies: Major obstacles and prospects for a solution

Science.gov (United States)

Bjarte H. Jordal

2007-01-01

To enable the resolution of deep phylogenetic divergence in Scolytinae and closely related weevils, several new molecular markers were screened for their phylogenetic potential. The nuclear protein encoding genes, CAD and Arginine Kinase, were particularly promising and will be added to future phylogenetic studies in combination with 28S, COI, and Elongation Factor 1...

Nuclear counterparts of the cytoplasmic mitochondrial 12S rRNA gene: a problem of ancient DNA and molecular phylogenies

NARCIS (Netherlands)

van der Kuyl, A. C.; Kuiken, C. L.; Dekker, J. T.; Perizonius, W. R.; Goudsmit, J.

1995-01-01

Monkey mummy bones and teeth originating from the North Saqqara Baboon Galleries (Egypt), soft tissue from a mummified baboon in a museum collection, and nineteenth/twentieth-century skin fragments from mangabeys were used for DNA extraction and PCR amplification of part of the mitochondrial 12S

Certification of U.S. instrumentation in Russian nuclear processing facilities

International Nuclear Information System (INIS)

Powell, D.H.; Sumner, J.N.

2000-01-01

Agreements between the United States (U.S.) and the Russian Federation (R.F.) require the down-blending of highly enriched uranium (HEU) from dismantled Russian Federation nuclear weapons. The Blend Down Monitoring System (BDMS) was jointly developed by the Los Alamos National Laboratory (LANL) and the Oak Ridge National Laboratory (ORNL) to continuously monitor the enrichments and flow rates in the HEU blending operations at the R.F. facilities. A significant requirement of the implementation of the BDMS equipment in R.F. facilities concerned the certification of the BDMS equipment for use in a Russian nuclear facility. This paper discusses the certification of the BDMS for installation in R.F. facilities, and summarizes the lessons learned from the process that can be applied to the installation of other U.S. equipment in Russian nuclear facilities

U.S. Nuclear Regulatory Commission Process for Risk-Informing the Nuclear Waste Arena

International Nuclear Information System (INIS)

Leslie, B. W.

2003-01-01

The U.S. Nuclear Regulatory Commission (NRC) is increasing the use of risk insights and information in its regulation of nuclear materials and waste. The objective of this risk-informed regulatory effort is to improve the effectiveness and efficiency of the agency, while maintaining or increasing its focus on safety. The agency's Office of Nuclear Material Safety and Safeguards (NMSS) proposed a five-step process to carry out a framework for increasing the use of risk information and insights in its regulation of nuclear materials and waste. The office is carrying out the five-step process to risk-inform the nuclear materials and waste arenas. NMSS's actions included forming a Risk Task Group and the use of case studies to test and complete screening criteria for identifying candidate regulatory applications amenable for risk-informing. Other actions included involving stakeholders through enhanced public participation, developing safety goals for materials and waste regulatory applications, and establishing a risk training program for staff. Through the case studies, NRC staff found the draft screening criteria to be effective in deciding regulatory areas that may be amenable to an increased use of risk insights. NRC staff also found that risk information may have the potential to reduce regulatory burden and improve staff's efficiency in making decisions, while maintaining safety. Finally, staff found that it would be possible to develop safety goals for the nuclear materials and waste arenas

A U.S. Minimum Nuclear Deterrence Strategy: By Design or Default It’s about the Policy Options

Science.gov (United States)

2012-06-01

then who are we to suggest actions that may upset the apple cart. Continued Retention of a Nuclear Deterrence Force. The ideas of M. K. Ghandi ...shaped India’s thinking about nuclear weapons. Ghandi espoused non-violence as a political strategy and his moral rejection of nuclear weapons laid the

Elecnuc. Nuclear power plants in the world; Elecnuc. Les centrales nucleaires dans le monde

Energy Technology Data Exchange (ETDEWEB)

NONE

2008-07-01

This small booklet summarizes in tables all data relative to the nuclear power plants worldwide. These data come from the IAEA's PRIS and AREVA-CEA's GAIA databases. The following aspects are reviewed: 2007 highlights; Main characteristics of reactor types; Map of the French nuclear power plants on 2007/01/01; Worldwide status of nuclear power plants (12/31/2007); Units distributed by countries; Nuclear power plants connected to the Grid- by reactor type groups; Nuclear power plants under construction on 2007; Evolution of nuclear power plants capacities connected to the grid; First electric generations supplied by a nuclear unit in each country; Electrical generation from nuclear power plants by country at the end 2007; Performance indicator of French PWR units; Evolution of the generation indicators worldwide by type; Nuclear operator ranking according to their installed capacity; Units connected to the grid by countries at 12/31/2007; Status of licence renewal applications in USA; Nuclear power plants under construction at 12/31/2007; Shutdown reactors; Exported nuclear capacity in net MWe; Exported and national nuclear capacity connected to the grid; Exported nuclear power plants under construction; Exported and national nuclear capacity under construction; Nuclear power plants ordered at 12/31/2007; Long term shutdown units at 12/31/2007; COL (combined licences) applications in the USA; Recycling of Plutonium in reactors and experiences; Mox licence plants projects; Appendix - historical development; Meaning of the used acronyms; Glossary.

Imagined Modernity. Nuclear Power and West German Society in the 1960s

International Nuclear Information System (INIS)

Metzler, G.

2012-01-01

In 1969 the first commercial nuclear power plant went into operation in West Germany, making the country a latecomer (compared to other Western countries) in the civilian use of nuclear energy. Yet, in the late 1950s and 1960s, nuclear energy played a major part in public debates on energy supply, on science and technology policy, and the relationship between state and the economy. The civilian use of atomic energy also served as a source of national identity and a projection of modernity. The paper seeks to connect analyses of technical, economic, political, and cultural developments, in order to assess the overall impact of nuclear power on West German society. (author)

Synthesis and Characterisation of Tris(1-carboxyl-2-phenyl-1,2-ethyl eno dithiol enic-S,S') Tungsten Complex as Photo catalyst for Photolysis of H2O Molecules

International Nuclear Information System (INIS)

Fadhli Hadana Rahman; Rusli Daik; Mohammad Kassim; Khuzaimah; Wan Ramli Wan Daud

2008-01-01

Tris(1-carboxyl-2-phenyl-1,2-ethylenodithiolenic-S,S ' ) tungsten complex is one of the most promising photo catalyst to be used in photolysis of water to produce hydrogen. The first step of the synthesis involves a metathesis reaction of tetrapropylammonium bromide [((C 3 H 7 ) 4 N)Br] and ammonium tetrathiotungstate [(NH 4 ) 2 WS 4 ] to form a tetrapropylammonium tetrathiotungstate [((C 3 H 7 ) 4 N) 2 WS 4 ] (precursor). Then, the precursor was reacted with phenyl acetylenecarboxylic acid (C 9 H 6 O 2 ) to form tris(1-carboxyl-2-phenyl-1,2-ethylenodithiolenic-S,S ' ) tungsten complex (C 27 H 18 O 2 S 6 W). The infra-red, ultra violet/ visible (UV/ Vis) spectrum, nuclear magnetic resonance (NMR) and elemental micro-analysis of C, H, N and S agreed with the characteristic of the tris(1-carboxyl-2-phenyl-1,2-ethylenodithiolenic-S,S ' ) tungsten complex. The (W-S), (C-S) and (C=O) stretching frequencies were detected at 511, (1470 and 1035) and 1655 cm -1 , respectively. The 1 H NMR spectrum showed six protons in the complex. The 13 C NMR showed only 7 signals for carbon atom in the benzene ring, ethylene groups and carboxylic acid pendant group due to the symmetry of the molecules. The reaction yield was about 50 percent. Photolysis of acetone spiked H 2 O showed that the catalyst was able to produced 1.8 μmol/ h hydrogen. (author)

Large dimuon asymmetry in B{sub s}-B-bar{sub s} mixing from unparticle induced {Gamma}{sub s}{sup 12}

Energy Technology Data Exchange (ETDEWEB)

Ren Bo [INPAC, Department of Physics, Shanghai Jiao Tong University, Shanghai (China); He Xiaogang, E-mail: hexg@phys.ntu.edu.t [INPAC, Department of Physics, Shanghai Jiao Tong University, Shanghai (China); Department of Physics and Center for Theoretical Sciences, National Taiwan University, Taipei, Taiwan (China); Xie Peichu [INPAC, Department of Physics, Shanghai Jiao Tong University, Shanghai (China)

2011-04-11

Exchange of unparticle stuff of dimension d{sub U} with FCNC interaction can induce M{sup 12,u} and {Gamma}{sup 12,u} causing meson and antimeson mixing with the relation {Gamma}{sup 12,u}/M{sup 12,u}=2tan({pi}d{sub U}). We show that this type of unparticle contribution can provide the much needed large {Gamma}{sub s}{sup 12} to explain the recently observed anomalously large dimuon asymmetry in B{sub s}-B-bar{sub s} system reported by D0 Collaboration. The same interaction can also accommodate large mixing induced CP violation in B{sub s{yields}}J/{psi}{phi} indicated by CDF and D0 data. Experimental data can provide constraints on the unparticle dimension and scale.

Conformational Entropy of FK506 Binding to FKBP12 Determined by Nuclear Magnetic Resonance Relaxation and Molecular Dynamics Simulations.

Science.gov (United States)

Solomentsev, Gleb; Diehl, Carl; Akke, Mikael

2018-03-06

FKBP12 (FK506 binding protein 12 kDa) is an important drug target. Nuclear magnetic resonance (NMR) order parameters, describing amplitudes of motion on the pico- to nanosecond time scale, can provide estimates of changes in conformational entropy upon ligand binding. Here we report backbone and methyl-axis order parameters of the apo and FK506-bound forms of FKBP12, based on 15 N and 2 H NMR relaxation. Binding of FK506 to FKBP12 results in localized changes in order parameters, notably for the backbone of residues E54 and I56 and the side chains of I56, I90, and I91, all positioned in the binding site. The order parameters increase slightly upon FK506 binding, indicating an unfavorable entropic contribution to binding of TΔ S = -18 ± 2 kJ/mol at 293 K. Molecular dynamics simulations indicate a change in conformational entropy, associated with all dihedral angles, of TΔ S = -26 ± 9 kJ/mol. Both these values are significant compared to the total entropy of binding determined by isothermal titration calorimetry and referenced to a reactant concentration of 1 mM ( TΔ S = -29 ± 1 kJ/mol). Our results reveal subtle differences in the response to ligand binding compared to that of the previously studied rapamycin-FKBP12 complex, despite the high degree of structural homology between the two complexes and their nearly identical ligand-FKBP12 interactions. These results highlight the delicate dependence of protein dynamics on drug interactions, which goes beyond the view provided by static structures, and reinforce the notion that protein conformational entropy can make important contributions to the free energy of ligand binding.

History of U.S. Nuclear Weapons Doctrine and a Path Forward

Science.gov (United States)

Chyba, Christopher

2007-04-01

During the Cold War, the United States considered a number of approaches for living in a world with nuclear weapons, including disarmament, preventive war, the incorporation of nuclear weapons into military strategy, passive and active defense, and deterrence. With the failure of early approaches to disarmament, and the rejection of preventive war against the Soviet Union (and later, China), deterrence became central to key nuclear relationships, though arms control continued to play an important role. The nuclear nonproliferation treaty made preventing the further spread of nuclear weapons another central component of U.S. policy. The Bush Administration has tried to devise a new policy for the post-Cold War period. Their approach has three salient pillars. First, it is characterized by an overall skepticism toward multilateral agreements, on the grounds that bad actors will not obey them, that agreements can lead to a false sense of security, and that such agreements are too often a way for the Lilliputians of the world to tie down Gulliver. The March 2005 U.S. National Defense Strategy declared that U.S. strength ``will continue to be challenged by those who employ a strategy of the weak, using international fora, judicial processes and terrorism.'' Second, the Bush Administration declared its intention to maintain a military dominance so great that other states simply would not try to catch up. The 2002 National Security Strategy states that ``Our forces will be strong enough to dissuade potential adversaries from pursuing a military build-up in hopes of surpassing, or equaling, the power of the United States.'' Third, the 2002 National Security Strategy (reaffirmed by the 2006 National Security Strategy) moved preventive war (which the strategies called ``preemptive war'') to a central position, rather than deterrence and nonproliferation. In part this was because of the claim that certain ``rogue'' states, and terrorist groups, were not deterrable. This talk

Analysis of North Korea's Nuclear Tests under Prospect Theory

Energy Technology Data Exchange (ETDEWEB)

Lee, Han Myung; Ryu, Jae Soo; Lee, Kwang Seok; Lee, Dong Hoon; Jun, Eunju; Kim, Mi Jin [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2013-10-15

North Korea has chosen nuclear weapons as the means to protect its sovereignty. Despite international society's endeavors and sanctions to encourage North Korea to abandon its nuclear ambition, North Korea has repeatedly conducted nuclear testing. In this paper, the reason for North Korea's addiction to a nuclear arsenal is addressed within the framework of cognitive psychology. The prospect theory addresses an epistemological approach usually overlooked in rational choice theories. It provides useful implications why North Korea, being under a crisis situation has thrown out a stable choice but taken on a risky one such as nuclear testing. Under the viewpoint of prospect theory, nuclear tests by North Korea can be understood as follows: The first nuclear test in 2006 is seen as a trial to escape from loss areas such as financial sanctions and regime threats; the second test in 2009 was interpreted as a consequence of the strategy to recover losses by making a direct confrontation against the United States; and the third test in 2013 was understood as an attempt to strengthen internal solidarity after Kim Jong-eun inherited the dynasty, as well as to enhance bargaining power against the United States. Thus, it can be summarized that Pyongyang repeated its nuclear tests to escape from a negative domain and to settle into a positive one. In addition, in the future, North Korea may not be willing to readily give up its nuclear capabilities to ensure the survival of its own regime.

China’s Foreign Policy Toward North Korea: The Nuclear Issue

Science.gov (United States)

2012-12-01

black or white, what matters is it catches mice ,” represented China’s strategy. Among Western countries, China understood that rapprochement with...nonproliferation issue. Until 1970, China considered that superpowers used nuclear nonproliferation as a way to monopolize nuclear weapons. Thus, in

Akt phosphorylation is essential for nuclear translocation and retention in NGF-stimulated PC12 cells

International Nuclear Information System (INIS)

Truong Le Xuan Nguyen; Choi, Joung Woo; Lee, Sang Bae; Ye, Keqiang; Woo, Soo-Dong; Lee, Kyung-Hoon; Ahn, Jee-Yin

2006-01-01

Nerve growth factor (NGF) elicits Akt translocation into the nucleus, where it phosphorylates nuclear targets. Here, we describe that Akt phosphorylation can promote the nuclear translocation of Akt and is necessary for its nuclear retention. Overexpression of Akt-K179A, T308A, S473A-mutant failed to show either nuclear translocation or nuclear Akt phosphorylation, whereas expression of wild-type counterpart elicited profound Akt phosphorylation and induced nuclear translocation under NGF stimulation. Employing the PI3K inhibitor and a variety of mutants PI3K, we showed that nuclear translocation of Akt was mediated by activation of PI3K, and Akt phosphorylation status in the nucleus required PI3K activity. Thus the activity of PI3K might contribute to the nuclear translocation of Akt, and that Akt phosphorylation is essential for its nuclear retention under NGF stimulation conditions

From Angra to Tehran: Brazilian nuclear policy under Lula’s administration

Directory of Open Access Journals (Sweden)

Diego Santos Vieira de JESUS

2011-11-01

Full Text Available The aim of this article is to explain the positions taken by Brazil under Lula’s administration (2003-2010 on nuclear non-proliferation, disarmament and arms control. In order to strengthen its position in dispute settlement and to expand its participation in international institutions, Brazil wished to intermediate between nuclear-weapon and non-nuclear weapon States. The country also tried to pressure the nuclear weapon States to fulfill their disarmament obligations and to reduce asymmetries in relations with the strongest countries in the nuclear arena. The Brazilians also sought to maintain flexibility to ensure the safety of their own atomic program.

Ductal carcinoma of breast: nuclear grade as a predictor of S-phase fraction.

Science.gov (United States)

Dabbs, D J

1993-06-01

Nuclear grade (NG) and S-phase fraction (SPF) are established independent prognostic variables for ductal breast carcinomas. Nuclear grade can be assigned by a pathologist in a simple fashion during histopathologic evaluation of the tumor, while SPF requires flow cytometric evaluation of tumor samples. This prospective study was undertaken to determine whether elevated SPF could be predicted from NG alone and how NG and SPF correlate with c-erbB-2 expression. Eighty-two breast carcinomas of ductal type were assigned an NG of low (grade 1 or grade 2) or high (grade 3). S-phase fraction was recorded initially from fresh-frozen tissue samples and was designated as either low SPF (below the value designated as the cutoff for elevated SPF) or high SPF (a value at or greater than the cutoff value). On fresh tissue the NG predicted the range of SPF (low or high) in 89% of cases. Four percent of the cases that did not correlate could definitely be attributed to sample error. The remaining 7% that did not correlate could have been due to sample error, specimen quality, or tumor heterogeneity, as demonstrated by reversal of SPF range as performed on paraffin blocks of tumor. Eighty-eight percent of the tumors positive for c-erbB-2 were NG 3 and 12% were NG 2. All c-erbB-2 tumors were aneuploid. This study demonstrates the importance of carefully assigning NGs on tissue and indicates the importance of reviewing flow cytometric data side by side with histopathologic parameters to detect discrepancies between these two modalities. Careful nuclear grading assignment can accurately predict the range of SPF.

The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model

Directory of Open Access Journals (Sweden)

Junrong Zhang

2016-11-01

Full Text Available Hericium erinaceus, an edible and medicinal mushroom, displays various pharmacological activities in the prevention of dementia in conditions such as Parkinson’s and Alzheimer’s disease. The present study explored the neuroprotective effects of H. erinaceus mycelium polysaccharide-enriched aqueous extract (HE on an l-glutamic acid (l-Glu-induced differentiated PC12 (DPC12 cellular apoptosis model and an AlCl3 combined with d-galactose-induced Alzheimer’s disease mouse model. The data revealed that HE successfully induced PC12 cell differentiation. A 3 h HE incubation at doses of 50 and 100 µg/mL before 25 mM of l-Glu effectively reversed the reduction of cell viability and the enhancement of the nuclear apoptosis rate in DPC12 cells. Compared with l-Glu-damaged cells, in PC12 cells, HE suppressed intracellular reactive oxygen species accumulation, blocked Ca2+ overload and prevented mitochondrial membrane potential (MMP depolarization. In the Alzheimer’s disease mouse model, HE administration enhanced the horizontal and vertical movements in the autonomic activity test, improved the endurance time in the rotarod test, and decreased the escape latency time in the water maze test. It also improved the central cholinergic system function in the Alzheimer’s mice, demonstrated by the fact that it dose-dependently enhanced the acetylcholine (Ach and choline acetyltransferase (ChAT concentrations in both the serum and the hypothalamus. Our findings provide experimental evidence that HE may provide neuroprotective candidates for treating or preventing neurodegenerative diseases.

The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model

Science.gov (United States)

Zhang, Junrong; An, Shengshu; Hu, Wenji; Teng, Meiyu; Wang, Xue; Qu, Yidi; Liu, Yang; Yuan, Ye; Wang, Di

2016-01-01

Hericium erinaceus, an edible and medicinal mushroom, displays various pharmacological activities in the prevention of dementia in conditions such as Parkinson’s and Alzheimer’s disease. The present study explored the neuroprotective effects of H. erinaceus mycelium polysaccharide-enriched aqueous extract (HE) on an l-glutamic acid (l-Glu)-induced differentiated PC12 (DPC12) cellular apoptosis model and an AlCl3 combined with d-galactose-induced Alzheimer’s disease mouse model. The data revealed that HE successfully induced PC12 cell differentiation. A 3 h HE incubation at doses of 50 and 100 µg/mL before 25 mM of l-Glu effectively reversed the reduction of cell viability and the enhancement of the nuclear apoptosis rate in DPC12 cells. Compared with l-Glu-damaged cells, in PC12 cells, HE suppressed intracellular reactive oxygen species accumulation, blocked Ca2+ overload and prevented mitochondrial membrane potential (MMP) depolarization. In the Alzheimer’s disease mouse model, HE administration enhanced the horizontal and vertical movements in the autonomic activity test, improved the endurance time in the rotarod test, and decreased the escape latency time in the water maze test. It also improved the central cholinergic system function in the Alzheimer’s mice, demonstrated by the fact that it dose-dependently enhanced the acetylcholine (Ach) and choline acetyltransferase (ChAT) concentrations in both the serum and the hypothalamus. Our findings provide experimental evidence that HE may provide neuroprotective candidates for treating or preventing neurodegenerative diseases. PMID:27809277

Economic and Market Challenges Facing the U.S. Nuclear Commercial Fleet

Energy Technology Data Exchange (ETDEWEB)

Szilard, Ronaldo [Idaho National Lab. (INL), Idaho Falls, ID (United States); Sharpe, Phil [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kee, Edward [Nuclear Economics Consulting Group, Washington, DC (United States); Davis, Edward [Nuclear Economics Consulting Group, Washington, DC (United States); Grecheck, Eugene [Grecheck Consulting LLC, Midlothian, VA (United States)

2016-09-01

This report identifies underlying economic and electricity market factors that have led to early retirements of U.S. operating nuclear power plants, assesses the Gap between operating revenues and operating costs for selected nuclear power plants, and discusses a range of actions that might be taken to stop early retirement of operating nuclear power plants. The Kewaunee and Vermont Yankee nuclear power plants were retired early for economic and financial reasons. Early retirement has been announced or proposed for Clinton and Quad Cities in Illinois, Fitzpatrick and Ginna in New York, Fort Calhoun in Nebraska. Other nuclear power plants, including Palisades, Davis-Besse, Prairie Island, and Three Mile Island Unit 1, have been identified as facing financial stress that might lead to early retirement. The early retirement of operating nuclear power plants will mean the loss of a large amount of zero-emission electricity, inconsistent with the goal of reducing carbon emissions in the electricity sector. This report provides a high-level view of the major factors driving early retirement: • The U.S. market and private ownership approach to the electricity sector; • Low electricity market prices resulting from low natural gas prices, low demand growth, increased penetration of renewable generation, and negative electricity market prices; and • No compensation to nuclear power plants for public benefits including zero-emission electricity.

Economic and Market Challenges Facing the U.S. Nuclear Commercial Fleet

International Nuclear Information System (INIS)

Szilard, Ronaldo; Sharpe, Phil; Kee, Edward; Davis, Edward; Grecheck, Eugene

2016-01-01

This report identifies underlying economic and electricity market factors that have led to early retirements of U.S. operating nuclear power plants, assesses the Gap between operating revenues and operating costs for selected nuclear power plants, and discusses a range of actions that might be taken to stop early retirement of operating nuclear power plants. The Kewaunee and Vermont Yankee nuclear power plants were retired early for economic and financial reasons. Early retirement has been announced or proposed for Clinton and Quad Cities in Illinois, Fitzpatrick and Ginna in New York, Fort Calhoun in Nebraska. Other nuclear power plants, including Palisades, Davis-Besse, Prairie Island, and Three Mile Island Unit 1, have been identified as facing financial stress that might lead to early retirement. The early retirement of operating nuclear power plants will mean the loss of a large amount of zero-emission electricity, inconsistent with the goal of reducing carbon emissions in the electricity sector. This report provides a high-level view of the major factors driving early retirement: • The U.S. market and private ownership approach to the electricity sector; • Low electricity market prices resulting from low natural gas prices, low demand growth, increased penetration of renewable generation, and negative electricity market prices; and • No compensation to nuclear power plants for public benefits including zero-emission electricity.

Nuclear Energy In Switzerland: It's going ahead. Challenges For The Swiss Nuclear Society Young Generation Group

Energy Technology Data Exchange (ETDEWEB)

Streit, Marco [Aare-Tessin Ltd for Electricity, Bahnhofquai 12, CH-4601 Olten (Switzerland); Bichsel, Thomas [BKW FMB Energie AG, NPP Muehleberg, CH-3203 Muehleberg (Switzerland); Fassbender, Andre [NPP Goesgen-Daeniken AG, CH-4658 Daeniken (Switzerland); Horvath, Matthias [National Emergency Operations Centre, CH-8044 Zurich (Switzerland)

2008-07-01

Swiss energy policy is focused on generating domestic electric power without combusting fossil fuels for already four decades. Roughly 60% of the electricity is generated in hydroelectric plants, which is possible due to the country's favourable topography; the remaining 40% are produced by the country's five nuclear power plants (NPPs). As in any other country nuclear power has its enemies in Switzerland. Due to the direct democracy system in Switzerland the nuclear opposition has a lot of possibilities to disturb the energy policy. Since 1969, when the first Swiss nuclear power plant went online, four plebiscites were held on the issue of civil use of nuclear energy. Four times Swiss citizens voted in favour of further operation of the existing plants also in the latest battle for nuclear energy, which was won in 2003. In 2005 and 2006 several Swiss studies about the future energy situation, especially the electricity situation, have been published. All off them show clearly that there will be a big gab around the year 2020 when the oldest three nuclear power plants will fade out. A public debate was started, how to solve the problem. Beside others, building new nuclear power plants was mentioned and discussed rationally. In 2007 the energy police of the Swiss government changed into a more nuclear friendly position and at the end of the same year some electricity companies lunched a new build program. Hosting the International Youth Nuclear Congress 2008 (IYNC 2008) in Switzerland seems to be just the right moment for the nuclear industry in our country. The slightly changed surroundings effected the organization of Swiss Nuclear Society (SNS) and SNS Young Generation Group (SNSYG) and enlarged the fields of activities for SNSYG. Those activities mentioned in the previous chapters will be developed in the future. The discussion about new builds in Switzerland has started and because of that more nuclear activities in Switzerland will occur. And surely

Assessing Kazakhstan´s Proposal to Host a Nuclear Fuel Bank

Directory of Open Access Journals (Sweden)

Caitlin A. Buckley

2012-01-01

Full Text Available Los defensores del control de armamentos buscan mecanismos para desincentivar la extensión de tecnologías sensibles para la proliferación. La mayoría de planes consideran situar las tecnologías del ciclo de combustible nuclear bajo un mayor control multilateral. Las propuestas para establecer uno o más bancos de combustible nuclear encajan claramente en este enfoque. Bajo este sistema, los países pueden "tomar prestado" el combustible que necesiten para sus reactores nucleares de un repositorio bajo control de la AIEA. Kazajstán ha ofrecido considerar el establecimiento de un banco internacional de combustible nuclear en su territorio. El país cuenta con ciertas características que podrían convertirlo en un buen candidato para un banco de combustible. Por ejemplo, Kazajstán es un actor destacado en el mercado internacional de uranio, tiene buenas relaciones con muchos países, y su gobierno cuenta con un historial sólido de no proliferación. Sin embargo, existe preocupación entre los observadores nacionales e internacionales acerca del ambicioso programa del gobierno kazajo, sus relaciones con países propensos a la proliferación, y la oposición de la sociedad en Kazajstán a las actividades nucleares.

Legislative Study on China’s Compensation for Nuclear Damage Liability

Directory of Open Access Journals (Sweden)

Jiu Liu

2018-06-01

Full Text Available The civil nuclear industry plays an important role in improving environmental quality and safeguarding energy security in China. Nevertheless, the industry is facing a huge risk of nuclear accident damage. The legal system of nuclear damage compensation is of vital importance for the industry to address potential risks. The Nuclear Safety Law, which has recently been published in China, stipulates two articles about nuclear damage compensation in principle. However, in general, the current nuclear damage compensation legal system in China has not yet been made systematic and there are still problems, such as a lack of maneuverability and details. This paper adopts qualitative and quantitative methodologies to summarize and analyze the current legislation and regulation pertaining to civil nuclear damage compensation liability in China and analyzes the shortages and deficiencies of these rules in detail by using legal analysis methods. Suggestions to establish and perfect China’s legal system of nuclear damage compensation are proposed to safeguard the healthy development of the civil nuclear industry and remedy damages brought about by nuclear accidents. Such a legal system should contain the elements of clear legislative goals and objectives, a specific definition and scope of nuclear damage, strict and sole responsibility principles for operators, an appropriate liability amount, a stable financial guarantee for operators, and national supplementary liability.

Initiating Event Rates at U.S. Nuclear Power Plants. 1988 - 2013

International Nuclear Information System (INIS)

Schroeder, John A.; Bower, Gordon R.

2014-01-01

Analyzing initiating event rates is important because it indicates performance among plants and also provides inputs to several U.S. Nuclear Regulatory Commission (NRC) risk-informed regulatory activities. This report presents an analysis of initiating event frequencies at U.S. commercial nuclear power plants since each plant's low-power license date. The evaluation is based on the operating experience from fiscal year 1988 through 2013 as reported in licensee event reports. Engineers with nuclear power plant experience staff reviewed each event report since the last update to this report for the presence of valid scrams or reactor trips at power. To be included in the study, an event had to meet all of the following criteria: includes an unplanned reactor trip (not a scheduled reactor trip on the daily operations schedule), sequence of events starts when reactor is critical and at or above the point of adding heat, occurs at a U.S. commercial nuclear power plant (excluding Fort St. Vrain and LaCrosse), and is reported by a licensee event report. This report displays occurrence rates (baseline frequencies) for the categories of initiating events that contribute to the NRC's Industry Trends Program. Sixteen initiating event groupings are trended and displayed. Initiators are plotted separately for initiating events with different occurrence rates for boiling water reactors and pressurized water reactors. p-values are given for the possible presence of a trend over the most recent 10 years.

75 FR 54917 - Criteria for Nominating Materials Licensees for the U.S. Nuclear Regulatory Commission's Agency...

Science.gov (United States)

2010-09-09

... NUCLEAR REGULATORY COMMISSION [NRC-2010-0294] Criteria for Nominating Materials Licensees for the U.S. Nuclear Regulatory Commission's Agency Action Review Meeting AGENCY: Nuclear Regulatory Commission. ACTION: Request for comment. SUMMARY: It is the policy of the U.S. Nuclear Regulatory Commission...

DPRK's 4{sup th} Nuclear Test and its Tritium Production

Energy Technology Data Exchange (ETDEWEB)

Kim, Min Soo; Lee, Sang Joon; Chang, Sun Young [Korea Institute of Nuclear Nonproliferation and Control, Daejeon (Korea, Republic of)

2016-05-15

On January 6, 2016 at 10:30am, the artificial earthquake in the DPRK was detected by multiple international seismic organizations. After 2 hours, the DPRK announced on state TV that 'The first H-bomb test was successfully conducted in the DPRK at 10:00 am on Wednesday, Juche 105(2016), pursuant to the strategic determination of the ruling communist party.' There has been a doubt about the real nature of the DPRK's 4th nuclear test, since 2 months have been passed after its nuclear test. To analyze the nature of the DPRK's nuclear test, it is necessary to check possible options for production of essential materials. The pathways to produce nuclear fusion material (tritium) and to have a relatively high possibility for the DPRK are described in this article. Tritium is key material for H-bomb. And there are two options for the DPRK which are 1) production and 2) illicit trafficking. And this study is focused on production possibility of DPRK. Determination of the nature of DPRK's nuclear test is very hard issue.

Q and A. Why the EC's PINC has failed Europe's nuclear industry

Energy Technology Data Exchange (ETDEWEB)

Kraev, Kamen [NucNet, Brussels (Belgium)

2016-12-15

The European Economic and Social Committee (EESC) has called for a more comprehensive strategy to be incorporated in a revised version of the European Commission's (EC) Illustrative Programme for Nuclear Energy (PINC). EESC member Brian Curtis tells NucNet why the PINC has failed to address key issues for nuclear and why he believes the EC has become side-tracked by renewables. The EESC is a consultative body which represents the interests of civil society organisations and stakeholders at the EU. Its opinions are forwarded to the EC, the European Council, and the European Parliament and are considered in the EU's decision-making process. Brian Curtis was rapporteur on the committee's opinion paper.

Morphological and molecular identification of marine copepod Dioithona rigida Giesbrecht, 1896 (Crustacea:Cyclopoida) based on mitochondrial COI gene sequences, from Lakshadweep sea, India.

Science.gov (United States)

Radhika, R; Bijoy Nandan, S; Harikrishnan, M

2017-11-01

Morphological identification of the marine cyclopoid copepod Dioithona rigida in combination with sequencing a 645 bp fragment of mitochondrial cytochrome oxidase c subunit I (mtCOI) gene, collected from offshore waters of Kavarathi Island, Lakshadweep Sea, is presented in this study. Kiefer in 1935 classified Dioithona as a separate genus from Oithona. The main distinguishing characters observed in the collected samples, such as the presence of well-developed P5 with 2 setae, 5 segmented urosome, 12 segmented antennule, compact dagger-like setae on the inner margin of proximal segment of exopod ramus in P1-P4 and engorged portion of P1-bearing a spine, confirmed their morphology to D. rigida. A comparison of setal formulae of the exopod and endopod of D. rigida with those recorded previously by various authors are also presented here. Maximum likelihood Tree analysis exhibited the clustering of D. rigida sequences into a single clade (accession numbers KP972540.1-KR528588.1), which in contrast was 37-42% divergent from other Oithona species. Further intra-specific divergence values of 0-2% also confirmed the genetic identity of D. rigida species. Paracyclopina nana was selected as an out group displayed a diverged array. The present results distinctly differentiated D. rigida from other Oithona species.

Concurrent speciation in the eastern woodland salamanders (Genus Plethodon):DNA sequences of the complete albumin nuclear and partialmitochondrial 12s genes

Science.gov (United States)

Highton, Richard; Hastings, Amy Picard; Palmer, Catherine; Watts, Richard; Hass, Carla A.; Culver, Melanie; Arnold, Stevan

2012-01-01

Salamanders of the North American plethodontid genus Plethodon are important model organisms in a variety of studies that depend on a phylogenetic framework (e.g., chemical communication, ecological competition, life histories, hybridization, and speciation), and consequently their systematics has been intensively investigated over several decades. Nevertheless, we lack a synthesis of relationships among the species. In the analyses reported here we use new DNA sequence data from the complete nuclear albumin gene (1818 bp) and the 12s mitochondrial gene (355 bp), as well as published data for four other genes (Wiens et al., 2006), up to a total of 6989 bp, to infer relationships. We relate these results to past systematic work based on morphology, allozymes, and DNA sequences. Although basal relationships show a strong consensus across studies, many terminal relationships remain in flux despite substantial sequencing and other molecular and morphological studies. This systematic instability appears to be a consequence of contemporaneous bursts of speciation in the late Miocene and Pliocene, yielding many closely related extant species in each of the four eastern species groups. Therefore we conclude that many relationships are likely to remain poorly resolved in the face of additional sequencing efforts. On the other hand, the current classification of the 45 eastern species into four species groups is supported. The Plethodon cinereus group (10 species) is the sister group to the clade comprising the other three groups, but these latter groups (Plethodon glutinosus [28 species], Plethodon welleri [5 species], and Plethodon wehrlei [2 species]) probably diverged from each other at approximately the same time.

Nuclear Energy Infrastructure Database Description and User’s Manual

Energy Technology Data Exchange (ETDEWEB)

Heidrich, Brenden [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2015-11-01

In 2014, the Deputy Assistant Secretary for Science and Technology Innovation initiated the Nuclear Energy (NE)–Infrastructure Management Project by tasking the Nuclear Science User Facilities, formerly the Advanced Test Reactor National Scientific User Facility, to create a searchable and interactive database of all pertinent NE-supported and -related infrastructure. This database, known as the Nuclear Energy Infrastructure Database (NEID), is used for analyses to establish needs, redundancies, efficiencies, distributions, etc., to best understand the utility of NE’s infrastructure and inform the content of infrastructure calls. The Nuclear Science User Facilities developed the database by utilizing data and policy direction from a variety of reports from the U.S. Department of Energy, the National Research Council, the International Atomic Energy Agency, and various other federal and civilian resources. The NEID currently contains data on 802 research and development instruments housed in 377 facilities at 84 institutions in the United States and abroad. The effort to maintain and expand the database is ongoing. Detailed information on many facilities must be gathered from associated institutions and added to complete the database. The data must be validated and kept current to capture facility and instrumentation status as well as to cover new acquisitions and retirements. This document provides a short tutorial on the navigation of the NEID web portal at NSUF-Infrastructure.INL.gov.

Iran’s geopolitics in Eurasia after the nuclear deal

Directory of Open Access Journals (Sweden)

Noemi Rocca

2017-06-01

Full Text Available Since the positive conclusion of the Iran nuclear deal, Iran is enhancing economic, military, energy and security ties with many countries, particularly with its Caucasus and Central Asian neighbours. Relations with Russia and China — which never stopped — are experiencing a new boom. Access to international financial markets — allowed by the progressive lifting of sanctions — coupled with the expected revenues from oil exports will modernise the Iranian industrial structure and make resources available for new infrastructure projects. This article approaches Iran’s geopolitics from a peculiar angle, that is through analysis of the offers Iran made in 2003 and 2005 to the United States and the European Union for solving the nuclear dispute. This article argues, firstly, that these proposals — focused not just on nuclear issues, but also on geopolitical matters — can shed light on how Iran shapes and conveys its geopolitical role in the Middle East and Central Asia; secondly, that such a role has been “legitimised” by global players like the United States, China, Russia, France, Germany, the United Kingdom and the European Union (i.e., the 5 + 1 countries which participated at the last round of the nuclear deal through the positive conclusion of the deal; and, finally, that Iran’s geopolitical role within the greater Eurasian space will increasingly assume more important dimensions.

A world class nuclear research reactor complex for South Africa's nuclear future

Energy Technology Data Exchange (ETDEWEB)

Keshaw, Jeetesh [South African Young Nuclear Professional Society, PO Box 9396, Centurion, 0157 (South Africa)

2008-07-01

South Africa recently made public its rather ambitious goals pertaining to nuclear energy developments in a Draft Policy and Strategy issued for public comment. Not much attention was given to an important tool for nuclear energy research and development, namely a well equipped and maintained research reactor, which on its own does not do justice to its potential, unless it is fitted with all the ancillaries and human resources as most first world countries have. In South Africa's case it is suggested to establish at least one Nuclear Energy Research and Development Centre at such a research reactor, where almost all nuclear energy related research can be carried out on par with some of the best in the world. The purpose of this work is to propose how this could be done, and motivate why it is important that it be done with great urgency, and with full involvement of young professionals, if South Africa wishes to face up to the challenges mentioned in the Draft Strategy and Policy. (authors)

Final Site-Wide Environmental Impact Statement for the Y-12 National Security Complex

International Nuclear Information System (INIS)

2001-01-01

The National Nuclear Security Administration (NNSA) a separately organized agency within the U.S. Department of Energy (DOE) is responsible for providing the Nation with nuclear weapons and ensuring that those nuclear weapons remain safe, secure, and reliable. As one of the DOE major production facilities, the Y-12 National Security Complex has been DOE's primary site for enriched uranium processing and storage, and one of the manufacturing facilities for maintaining the U.S. nuclear weapons stockpile. In response to the end of the Cold War and changes in the world's political regimes, the emphasis of the U.S. weapons program has shifted dramatically over the past few years from developing and producing new weapons to dismantlement and maintenance of a smaller, enduring stockpile. The ''Stockpile Stewardship and Management Programmatic Environmental Impact Statement'' [SSM PEIS], DOE/EIS-0236, issued in September 1996, evaluated alternatives for maintaining the safety and reliability of the nuclear weapons stockpile without underground nuclear testing or production of new-design weapons. In the SSM PEIS Record of Decision (ROD), DOE decided to maintain the national security missions at the Y-12 National Security Complex, but to downsize Y-12 consistent with reduced requirements. These national security missions include (1) maintaining the capability and capacity to fabricate secondaries, limited life components, and case parts for nuclear response; (2) evaluating components and subsystems returned from the stockpile; (3) storing enriched uranium that is designated for national security purposes; (4) storing depleted uranium and lithium parts; (5) dismantling nuclear weapons secondaries returned from the stockpile; (6) processing uranium and lithium (which includes chemical recovery, purification, and conversion of enriched uranium and lithium to a form suitable for long-term storage and/or further use); and (7) providing support to weapons laboratories. During the

Synthesis optimisation and characterisation of the organic-inorganic layered materials ZnS(m-xylylenediamine){sub 1/2} and ZnS(p-xylylenediamine){sub 1/2}

Energy Technology Data Exchange (ETDEWEB)

Luberda-Durnaś, K. [Institute of Geological Sciences PAS, Research Centre in Krakow, Senacka 1, Krakow 31-002 (Poland); Guillén, A. González [Faculty of Chemistry, Jagiellonian University, Ingardena 3, Krakow 30-060 (Poland); Łasocha, W., E-mail: lasocha@chemia.uj.edu.pl [Jerzy Haber Institute of Catalysis and Surface Chemistry PAS, Niezapominajek 8, Krakow 30-239 (Poland); Faculty of Chemistry, Jagiellonian University, Ingardena 3, Krakow 30-060 (Poland)

2016-06-15

Hybrid organic-inorganic layered materials of the type ZnS(amine){sub 1/2}, where amine=m-xylylenediamine (MXDA) or p-xylylenediamine (PXDA), were synthesised using a simple solvothermal method. Since the samples crystallised in the form of very fine powder, X-ray powder diffraction techniques were used for structural characterisation. The crystal structure studies, involving direct methods, show that both compounds crystallised in the orthorhombic crystal system, but in different space groups: ZnS(MXDA){sub 1/2} in non-centrosymmetric Ccm2{sub 1}, ZnS(PXDA){sub 1/2} in centrosymmetric Pcab. The obtained materials are built according to similar orders: semiconducting monolayers with the formula ZnS, parallel to the (010) plane, are separated by diamines. The organic and inorganic fragments are connected by covalent bonds between metal atoms of the layers and nitrogen atoms of the amino groups. The optical properties of the hybrid materials differ from those of their bulk counterpart. In both compounds a blue-shift of about 0.8 or 0.9 eV was observed with reference to the bulk phase of ZnS. - Highlights: • New hybrid compounds: ZnS(MXDA){sub 1/2} and ZnS(PXDA){sub 1/2} were obtained. • Hybrids were studied using XRD, TG/DSC, XRK, SEM, UV–vis spectroscopy. • Structures of both materials were solved by powder diffraction methods.

U.S. congressional attitudes and policies affecting nuclear power development in the world

International Nuclear Information System (INIS)

McCormack, M.

1976-01-01

The world future for nuclear power is even now being formed by policies and decisions of many governments and international organizations. Congressman McCormack looks to the United States for revived and stronger leadership in strengthening the web of institutions and international relations to permit the world to reap the benefits of nuclear power without a destabilizing spread of nuclear weapons. He says Congress will have a major role in shaping that nuclear future. The tensions between Congress and the executive branch that are part of the U.S. system of separation of powers can help to test and strengthen future policy on international nuclear power. The point of no return along the course of nuclear evolution is approaching and the author asks: will we press on to create an acceptable balance between benefits of nuclear power and the risk that expanded use may increase proliferation--or will we turn back toward nuclear isolationism. Mr. McCormack opts for vigorous legislative, executive and diplomatic initiatives to sustain U.S. nuclear leadership so that we can accelerate and influence world measures to prevent proliferation while developing uranium and thorium as future world energy resources

First large-scale DNA barcoding assessment of reptiles in the biodiversity hotspot of Madagascar, based on newly designed COI primers.

Science.gov (United States)

Nagy, Zoltán T; Sonet, Gontran; Glaw, Frank; Vences, Miguel

2012-01-01

DNA barcoding of non-avian reptiles based on the cytochrome oxidase subunit I (COI) gene is still in a very early stage, mainly due to technical problems. Using a newly developed set of reptile-specific primers for COI we present the first comprehensive study targeting the entire reptile fauna of the fourth-largest island in the world, the biodiversity hotspot of Madagascar. Representatives of the majority of Madagascan non-avian reptile species (including Squamata and Testudines) were sampled and successfully DNA barcoded. The new primer pair achieved a constantly high success rate (72.7-100%) for most squamates. More than 250 species of reptiles (out of the 393 described ones; representing around 64% of the known diversity of species) were barcoded. The average interspecific genetic distance within families ranged from a low of 13.4% in the Boidae to a high of 29.8% in the Gekkonidae. Using the average genetic divergence between sister species as a threshold, 41-48 new candidate (undescribed) species were identified. Simulations were used to evaluate the performance of DNA barcoding as a function of completeness of taxon sampling and fragment length. Compared with available multi-gene phylogenies, DNA barcoding correctly assigned most samples to species, genus and family with high confidence and the analysis of fewer taxa resulted in an increased number of well supported lineages. Shorter marker-lengths generally decreased the number of well supported nodes, but even mini-barcodes of 100 bp correctly assigned many samples to genus and family. The new protocols might help to promote DNA barcoding of reptiles and the established library of reference DNA barcodes will facilitate the molecular identification of Madagascan reptiles. Our results might be useful to easily recognize undescribed diversity (i.e. novel taxa), to resolve taxonomic problems, and to monitor the international pet trade without specialized expert knowledge.

Phylogenetic relationship of the Brazilian isolates of the rat lungworm Angiostrongylus cantonensis (Nematoda: Metastrongylidae) employing mitochondrial COI gene sequence data.

Science.gov (United States)

Monte, Tainá C C; Simões, Raquel O; Oliveira, Ana Paula M; Novaes, Clodoaldo F; Thiengo, Silvana C; Silva, Alexandre J; Estrela, Pedro C; Maldonado, Arnaldo

2012-11-06

The rat lungworm Angiostrongylus cantonensis can cause eosinophilic meningoencephalitis in humans. This nematode's main definitive hosts are rodents and its intermediate hosts are snails. This parasite was first described in China and currently is dispersed across several Pacific islands, Asia, Australia, Africa, some Caribbean islands and most recently in the Americas. Here, we report the genetic variability among A. cantonensis isolates from different geographical locations in Brazil using mitochondrial cytochrome c oxidase subunit I (COI) gene sequences. The isolates of A. cantonensis were obtained from distinct geographical locations of Brazil. Genomic DNAs were extracted, amplified by polymerase reaction, purified and sequenced. A partial sequence of COI gene was determined to assess their phylogenetic relationship. The sequences of A. cantonensis were monophyletic. We identified a distinct clade that included all isolates of A. cantonensis from Brazil and Asia based on eight distinct haplotypes (ac1, ac2, ac3, ac4, ac5, ac6, ac7 and ac8) from a previous study. Interestingly, the Brazilian haplotype ac5 is clustered with isolates from Japan, and the Brazilian haplotype ac8 from Rio de Janeiro, São Paulo, Pará and Pernambuco states formed a distinct clade. There is a divergent Brazilian haplotype, which we named ac9, closely related to Chinese haplotype ac6 and Japanese haplotype ac7. The genetic variation observed among Brazilian isolates supports the hypothesis that the appearance of A. cantonensis in Brazil is likely a result of multiple introductions of parasite-carrying rats, transported on ships due to active commerce with Africa and Asia during the European colonization period. The rapid spread of the intermediate host, Achatina fulica, also seems to have contributed to the dispersion of this parasite and the infection of the definitive host in different Brazilian regions.

U.S. Nuclear Power Plant Operating Cost and Experience Summaries

International Nuclear Information System (INIS)

Reid, RL

2003-01-01

The ''U.S. Nuclear Power Plant Operating Cost and Experience Summaries'' (NUREG/CR-6577, Supp. 2) report has been prepared to provide historical operating cost and experience information on U.S. commercial nuclear power plants during 2000-2001. Costs incurred after initial construction are characterized as annual production costs, which represent fuel and plant operating and maintenance expenses, and capital expenditures related to facility additions/modifications, which are included in the plant capital asset base. As discussed in the report, annual data for these two cost categories were obtained from publicly available reports and must be accepted as having different degrees of accuracy and completeness. Treatment of inconclusive and incomplete data is discussed. As an aid to understanding the fluctuations in the cost histories, operations summaries for each nuclear unit are provided. The intent of these summaries is to identify important operating events; refueling, major maintenance, and other significant outages; operating milestones; and significant licensing or enforcement actions. Information used in the summaries is condensed from operating reports submitted by the licensees, the Nuclear Regulatory Commission (NRC) database for enforcement actions, and outage reports

12 CFR 619.9140 - Farm Credit bank(s).

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Farm Credit bank(s). 619.9140 Section 619.9140 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM DEFINITIONS § 619.9140 Farm Credit bank(s). Except as otherwise defined, the term Farm Credit bank(s) includes Farm Credit Banks...

A molecular phylogeny of the Cephinae (Hymenoptera, Cephidae based on mtDNA COI gene: a test of traditional classification

Directory of Open Access Journals (Sweden)

Mahir Budak

2011-09-01

Full Text Available Cephinae is traditionally divided into three tribes and about 24 genera based on morphology and host utilization. There has been no study testing the monophyly of taxa under a strict phylogenetic criterion. A molecular phylogeny of Cephinae based on a total of 68 sequences of mtDNA COI gene, representing seven genera of Cephinae, is reconstructed to test the traditional limits and relationships of taxa. Monophyly of the traditional tribes is not supported. Monophyly of the genera are largely supported except for Pachycephus. A few host shift events are suggested based on phylogenetic relationships among taxa. These results indicate that a more robust phylogeny is required for a more plausible conclusion. We also report two species of Cephus for the first time from Turkey.

Canada's deadly secret : Saskatchewan uranium and the global nuclear system

Energy Technology Data Exchange (ETDEWEB)

Harding, J.

2007-07-01

Although Canada has a reputation for its support of multilateralism and international peacekeeping, it has provided fuel for American and British nuclear weapons, and continues to provide uranium fuel for nuclear reactors and power plants throughout the world. This book provided a detailed outline of Canada's involvement in uranium mining in Saskatchewan, the largest uranium-producing region in the world. The ways in which Canada has been complicit in the expansion of the global nuclear system were examined. A history of the province's role in the first nuclear arms race between the Soviet Union and the United States was provided, and details of provincial public inquiries conducted to legitimize the expansion of uranium mining were revealed. Issues related to the exploitation of ancestral lands belonging to Aboriginal peoples were discussed along with the impact of uranium mining on communities in the province. It was concluded that the province is now being targeted as a storage site for nuclear waste. refs.

U.S. Nuclear Weapons: Changes in Policy and Force Structure

National Research Council Canada - National Science Library

Woolf, Amy F

2004-01-01

.... Although the review sought to adjust the U.S. nuclear posture to address changes in the international security environment at the start of the new century, it continued many of the policies and programs that had been a part of the U.S...

U.S. Nuclear Weapons: Changes in Policy and Force Structure

National Research Council Canada - National Science Library

Woolf, Amy F

2002-01-01

.... Although the review sought to adjust U.S. nuclear posture to address changes in the international security environment at the start of the new century, it continued many of the policies and programs that had been a part of the U.S...

U.S. Nuclear Weapons: Changes in Policy and Force Structure

National Research Council Canada - National Science Library

Woolf, Amy F

2006-01-01

.... Although the review sought to adjust U.S. nuclear posture to address changes in the international security environment at the start of the new century, it continued many of the policies and programs that had been a part of the U.S...

U.S. Nuclear Weapons: Changes in Policy and Force Structure

National Research Council Canada - National Science Library

Woolf, Amy F

2005-01-01

.... Although the review sought to adjust U.S. nuclear posture to address changes in the international security environment at the start of the new century, it continued many of the policies and programs that had been a part of the U.S...

French Nuclear Forces in the 1980s and 1990s

Science.gov (United States)

1983-08-01

the mid-1990s, the new force structure will be theoretically capable of inflicting massive destruc- tion against the Soviet Union as well as...capacity which turns national territory into a sanctuary. The current French nuclear force structure is shown in table 1 below. -2- TABLE 1 FRENCH...out in favor of the M-2 in 1974 which by 1977 had itself been supplanted by the M-20. The first Sous-marin Nucleaire Lanceur d’Engins I (SNLE) or

U.S. commercial nuclear power: a status report

International Nuclear Information System (INIS)

Cleark, R.G.; Reynolds, A.W.

1977-09-01

The current and forecasted status of the domestic nuclear power program is discussed in the context of the proposed National Energy Plan. Nuclear power is expected to increase its contribution to the Nation's electricity generation from 9.4 percent in 1976 to 13 percent in 1980 and 18 percent in 1985. Indigenous uranium reserves and resources appear adequate to allow a continued expansion of the national reactor system, but the annual production capacity of the domestic uranium industry must be significantly expanded to support this generating forecast. U.S. uranium enrichment capacity will also be adequate if ongoing expansion programs and the planned Portsmouth centrifuge addition are realized. However, domestic uranium demand and price, and the Administration's desire to accept new orders for enrichment services, are sensitive to Energy Research and Development Administration's enrichment contract stipulations and plant operating modes. Current U.S. policy has resulted in the deferral of the plutonium and uranium recycle option for the intermediate future, and a shift in post-reactor attention from reprocessing-recycle to unresolved programs for spent fuel storage and radioactive waste management. The comparative economics of nuclear-fueled and coal-fired generating systems vary among geographical regions, but generally, costs are so similar that modest changes in fuel or operating parameters could reverse the relative advantage of one option over the other

Strangeness nuclear physics

International Nuclear Information System (INIS)

Imai, Kenichi

1999-01-01

A simple review of strangeness nuclear physics is stated in the order of introduction, generation, structure and decay of hyper-nucleus and S=-2 nuclear physics. Strangeness nuclear physics investigate the structure and nuclear force of new created nucleus by introducing strangeness to the nuclear matter. The fundamental problems are hyperon-nucleon and hyperon-hyperon interaction. There are many methods to generate hyper nucleus. The stopped K - reaction is the best one. Λ and S hyper and S=-2 nucleus were generated by (K - , π) and (π + , K + ) reaction, (K - , π) reaction and (K - , K + ) reaction, respectively. The elementary decay process in the nucleus is Λ - > pπ (Q=38 MeV), nπ 0 and Λp - > np (Q=176 MeV), Λn- > nn. In emulsion, mass of light nucleus less than 160 were determined. Two measurement units are stated. One of them is a double focusing type K beam line in BNL to investigate H dibaryon by (K - , K + ) reaction. The other is KEK-SKS, which is superconducting kaon spectrometer to study hyper nucleus by (π + , K + ) reaction. The various kinds of binding energy of Λ single-particle states are displayed as a function of A -2/3 . These experimental data fit well with DWIA calculation using Woods-Saxon type one-body potential. A spectrum of 12C (π + , K + ) reaction showed small peak without main two peaks, which was a hyperfine structure between the exited state of 11 C core and couple of s 1/2 Λ. Although γ-ray was detected by three nucleuses such as 4 HΛ, 7 Li Λ and 9 Be Λ , γ-ray spectrometry of hyper nucleus remains unexplored. E hyper nucleus is detected by 4He(K-, t) and not by 4 He (K - , π + ). The binding energy of 4He Σ is 4.4 + 1 MeV and the width 7.0 + 0.7 MeV. Λ hyper nucleus decay is occurred by weak interaction. The elementary processes are a mesonic decay of Λ - > pπ - and Λ - > nπ 0 and a nonmesonic decay of Λn - > nn and Λp- > np. The lifetime of hyper nucleus is shorter than free Λ. Subject of S=-2 nuclear

Is nuclear structure relevant to non-mesonic hyper-nuclear weak decay?

International Nuclear Information System (INIS)

Wu, H.C.; Aristizabal, M.F.; Ponce, W.A.

2002-01-01

This work studies the relevance of nuclear structure in the non-mesonic weak decay of Λ-hypernuclei, with the mechanism of ΛN → NN transition being restricted to one pion exchange (OPE) only. As an application, for the hypernucleus Λ 12 C a comparison between the L-S coupling and the j-j coupling gives an estimate of the range of nuclear structure effects. A considerable dependence is found of the total decay rate and the ratio Γ n /Γ p on the single particle properties of nuclear models. The possible contribution from the ΔI = 3/2 channel is investigated in a phenomenological manner. (author)

Economic Analysis for Nuclear Hydrogen Production System Based on HyS Process

International Nuclear Information System (INIS)

Yang, Kyeong Jin; Lee, Ki Young; Lee, Tae Hoon; Chang, Jong Hwa

2009-01-01

The current promising base for massive hydrogen production on high temperature environment derives primarily from three sources: the commercial production of chemicals for the sulfur-iodine (SI) process, the development of solid-oxide fuel cells (SOFC), and the hybrid method of chemicals and fuel cells. The three kinds of process requires high temperature heat energy over 850∼950 .deg. C for the efficient and economic hydrogen production. One of the clean, economic, and moreover promising heat sources supplied to the process is nuclear plants. The nuclear plants producing high temperature heat energy over 950 .deg. C are well known as Very High Temperature Reactors (VHTR) which could have two types of prismatic and pebble-bed cores along reactor core shape. In this paper, we report on the Hybrid Sulfur Process (HyS), and the estimated costs for the system which composes of VHTR of prismatic core type and HyS plant. Nuclear hydrogen production system based on HyS process has been configured to optimally use the thermal energy from VHTR and electric energy to produce hydrogen and oxygen from clean water. High temperature thermal energy is transferred to the HyS process by way of intermediate heat exchanger (IHX) with associated piping. In this paper, the hydrogen production costs for a system composed of a VHTR with six 600MWth module, a power conversion unit (PCU) and a HyS plant are presented, where the thermal energy produced in two module was converted to electric energy in PCU and then transferred to the electrolysis cells for hydrogen production and circulating units on HyS plant, and the remaining thermal energy was supplied to chemical process on HyS plants. As a preliminary study of cost estimates for nuclear hydrogen systems, the hydrogen production costs of the nuclear energy sources benchmarking GT-MHR are estimated in the necessary input data on a Korean specific basis. G4- ECONS was appropriately modified to calculate the cost for hydrogen production

IRSN's Position on Safety and Radiation Protection at Nuclear Power Plants in France, 2012

International Nuclear Information System (INIS)

2014-01-01

After working a year to consolidate the data, the annual report on the radiation protection and safety of nuclear power plants in France gives the IRSN's independent point of view on all progress and problems concerning safety and radiation protection encountered in the French nuclear power plant fleet in 2012. The first part of the report presents the main trends that emerge from IRSN's overall assessment of the radiation protection and safety performance of currently operating nuclear power plants for the year 2012. The year 2012 has witnessed an increase in the total number of significant events. However, IRSN notes the absence in 2012 of incidents with a potentially significant impact on nuclear power plant safety, the surrounding environment or nearby communities in a context of large-scale personnel renewal. This increase can mainly be explained by EDF's implementation of an improved nonconformance detection and handling procedure which led to the identification, in 2012, of various non-conformances presumably present for several years but previously undetected. With regard to radiation protection, IRSN notes that the effective dose received by the majority of exposed workers over a period of 12 consecutive months is below the annual public radiation dose limit. Faults may occur with nuclear power plant equipment or reactor monitoring systems. Given the standardisation of EDF nuclear power plant reactors, such faults may affect an entire reactor series or even the entire reactor fleet. A few examples deemed particularly significant by IRSN are presented in the second part of this report. French nuclear reactors are subject to modifications throughout their operating lives, particularly with a view to ensuring continuous safety improvement, this is the subject of the third part of the report. Most of these modifications are the result of studies conducted within the framework of ten-yearly safety reviews, leading to the definition and

(2S,7S-10-Ethyl-1,8,10,12-tetraazatetracyclo[8.3.1.18,12.02,7]pentadecan-10-ium iodide

Directory of Open Access Journals (Sweden)

Augusto Rivera

2012-10-01

Full Text Available The title chiral quaternary ammonium salt, C13H25N4+·I−, was synthesized through the Menschutkin reaction between the cage aminal (2S,7S-1,8,10,12-tetraazatetracyclo[8.3.1.18,12.02,7]pentadecane and ethyl iodide. The quaternization occurred regioselectively on the nitrogen with major sp3 character. The crystal structure consists of anions and cations separated by normal distances. Ions are not linked through C—H...I hydrogen bonds.

Undergraduate education in nuclear engineering in the USA

International Nuclear Information System (INIS)

Martin, W.R.

1993-01-01

The discipline of nuclear engineering is described, giving some historical background to explain the structure of the curricula commonly found in nuclear engineering programs in the U.S. Typical curricula are described, along with a specific example given by the University of Michigan undergraduate program in nuclear engineering. The National Academy of Sciences report on U.S. nuclear engineering education is summarized, and the major findings are presented, including data on the number of programs, number of degrees, and enrollment trends. Some discussion is made of manpower trends and the degree to which nuclear programs can supply nuclear engineers to meet the anticipated demands of the current decade and into the next century. (author) 12 refs.; 2 figs.; 4 tabs

Standard Specification for Nuclear Facility Transient Worker Records

CERN Document Server

American Society for Testing and Materials. Philadelphia

1995-01-01

1.1 This specification covers the required content and provides retention requirements for records needed for in-processing of nuclear facility transient workers. 1.2 This specification applies to records to be used for in-processing only. 1.3 This specification is not intended to cover specific skills records (such as equipment operating licenses, ASME inspection qualifications, or welding certifications). 1.4 This specification does not reduce any regulatory requirement for records retention at a licensed nuclear facility. Note 1—Nuclear facilities operated by the U.S. Department of Energy (DOE) are not licensed by the U.S. Nuclear Regulatory Commission (NRC), nor are other nuclear facilities that may come under the control of the U.S. Department of Defense (DOD) or individual agreement states. The references in this specification to licensee, the U.S. NRC Regulatory Guides, and Title 10 of the U.S. Code of Federal Regulations are to imply appropriate alternative nomenclature with respect to DOE, DOD...

Decreased nuclear stiffness via FAK-ERK1/2 signaling is necessary for osteopontin-promoted migration of bone marrow-derived mesenchymal stem cells

Energy Technology Data Exchange (ETDEWEB)

Liu, Lingling, E-mail: liulingling2012@163.com [Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044 (China); Luo, Qing, E-mail: qing.luo@cqu.edu.cn [Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044 (China); Sun, Jinghui, E-mail: sunjhemail@163.com [Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044 (China); Wang, Aoli, E-mail: leaf13332@163.com [Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044 (China); Shi, Yisong, E-mail: shiyis@cqu.edu.cn [Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044 (China); Ju, Yang, E-mail: ju@mech.nagoya-u.ac.jp [Department of Mechanical Science and Engineering, Nagoya University, Nagoya 464-8603 (Japan); Morita, Yasuyuki, E-mail: morita@mech.nagoya-u.ac.jp [Department of Mechanical Science and Engineering, Nagoya University, Nagoya 464-8603 (Japan); Song, Guanbin, E-mail: song@cqu.edu.cn [Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044 (China)

2017-06-15

Migration of bone marrow-derived mesenchymal stem cells (BMSCs) plays an important role in many physiological and pathological settings, including wound healing. During the migration of BMSCs through interstitial tissues, the movement of the nucleus must be coordinated with the cytoskeletal dynamics, which in turn affects the cell migration efficiency. Our previous study indicated that osteopontin (OPN) significantly promotes the migration of rat BMSCs. However, the nuclear behaviors and involved molecular mechanisms in OPN-mediated BMSC migration are largely unclear. In the present study, using an atomic force microscope (AFM), we found that OPN could decrease the nuclear stiffness of BMSCs and reduce the expression of lamin A/C, which is the main determinant of nuclear stiffness. Increased lamin A/C expression attenuates BMSC migration by increasing nuclear stiffness. Decreased lamin A/C expression promotes BMSC migration by decreasing nuclear stiffness. Furthermore, OPN promotes BMSC migration by diminishing lamin A/C expression and decreasing nuclear stiffness via the FAK-ERK1/2 signaling pathway. This study provides strong evidence for the role of nuclear mechanics in BMSC migration as well as new insight into the molecular mechanisms of OPN-promoted BMSC migration. - Highlights: • OPN promotes BMSC migration by decreasing nuclear stiffness. • Lamin A/C knockdown decreases, while its overexpression enhances, the nuclear stiffness of BMSCs. • Lamin A/C overexpression and downregulation affect the migration of BMSCs. • OPN diminishes lamin A/C expression and decreases nuclear stiffness through the activation of the FAK-ERK1/2 signaling pathway. • OPN promotes BMSC migration via the FAK-ERK1/2 signaling pathway.

Decreased nuclear stiffness via FAK-ERK1/2 signaling is necessary for osteopontin-promoted migration of bone marrow-derived mesenchymal stem cells

International Nuclear Information System (INIS)

Liu, Lingling; Luo, Qing; Sun, Jinghui; Wang, Aoli; Shi, Yisong; Ju, Yang; Morita, Yasuyuki; Song, Guanbin

2017-01-01

Migration of bone marrow-derived mesenchymal stem cells (BMSCs) plays an important role in many physiological and pathological settings, including wound healing. During the migration of BMSCs through interstitial tissues, the movement of the nucleus must be coordinated with the cytoskeletal dynamics, which in turn affects the cell migration efficiency. Our previous study indicated that osteopontin (OPN) significantly promotes the migration of rat BMSCs. However, the nuclear behaviors and involved molecular mechanisms in OPN-mediated BMSC migration are largely unclear. In the present study, using an atomic force microscope (AFM), we found that OPN could decrease the nuclear stiffness of BMSCs and reduce the expression of lamin A/C, which is the main determinant of nuclear stiffness. Increased lamin A/C expression attenuates BMSC migration by increasing nuclear stiffness. Decreased lamin A/C expression promotes BMSC migration by decreasing nuclear stiffness. Furthermore, OPN promotes BMSC migration by diminishing lamin A/C expression and decreasing nuclear stiffness via the FAK-ERK1/2 signaling pathway. This study provides strong evidence for the role of nuclear mechanics in BMSC migration as well as new insight into the molecular mechanisms of OPN-promoted BMSC migration. - Highlights: • OPN promotes BMSC migration by decreasing nuclear stiffness. • Lamin A/C knockdown decreases, while its overexpression enhances, the nuclear stiffness of BMSCs. • Lamin A/C overexpression and downregulation affect the migration of BMSCs. • OPN diminishes lamin A/C expression and decreases nuclear stiffness through the activation of the FAK-ERK1/2 signaling pathway. • OPN promotes BMSC migration via the FAK-ERK1/2 signaling pathway.

Cluster-spin dynamics in a GaMo{sub 4}S{sub 8}-type compound: {sup 27}Al nuclear magnetic resonance study of AlMo{sub 4}S{sub 8}

Energy Technology Data Exchange (ETDEWEB)

Ikeno, R; Nakamura, H; Kohara, T [Graduate School of Material Science, University of Hyogo, Kamigori, Ako-gun, Hyogo 678-1297 (Japan)

2007-01-31

The cluster-spin dynamics of the tetrahedral Mo{sub 4} cluster, involved in AlMo{sub 4}S{sub 8} with a cubic GaMo{sub 4}S{sub 8} type structure, was investigated by NMR of the nonmagnetic {sup 27}Al site located outside the cluster. The nuclear spin-lattice relaxation is described well by the conventional local moment model assuming the presence of S=1/2 at each cluster, indicating that each Mo{sub 4} cluster behaves like a local spin with rigid magnitude. This behaviour is in contrast to the in-cluster relaxation, which reflects the spin-density fluctuations inside the cluster as a small unit of metal.

Glycogen synthase kinase 3-{beta} phosphorylates novel S/T-P-S/T domains in Notch1 intracellular domain and induces its nuclear localization

Energy Technology Data Exchange (ETDEWEB)

Han, Xiangzi [Department of Life Science, College of Natural Sciences, Hanyang University, Seoul 133-791 (Korea, Republic of); Department of Preventive Medicine, Yanbian University College of Medicine, Yanji (China); Ju, Ji-hyun [Department of Life Science, College of Natural Sciences, Hanyang University, Seoul 133-791 (Korea, Republic of); Shin, Incheol, E-mail: incheol@hanyang.ac.kr [Department of Life Science, College of Natural Sciences, Hanyang University, Seoul 133-791 (Korea, Republic of)

2012-06-29

Highlights: Black-Right-Pointing-Pointer Novel S/T-P-S/T domains were identified in NICD. Black-Right-Pointing-Pointer Phosphorylation of NICD on the S/T-P-S/T domains induced nuclear localization. Black-Right-Pointing-Pointer GSK-3{beta} phosphorylated S and T residues in NICD S/T-P-S/T domains. -- Abstract: We identified two S/T-P-S/T domains (2122-2124, 2126-2128) inducing Notch intracellular domain (NICD) nuclear localization. The GFP-NICD (1963-2145) fusion protein deletion mutant without classical NLS was localized in the nucleus like the full length GFP-NICD. However, quadruple substitution mutant (T2122A T2124A S2126A T2128A) showed increased cytoplasmic localization. GSK-3{beta} enhanced nuclear localization and transcriptional activity of WT NICD but not of quadruple substitution mutant. In vitro kinase assays revealed that GSK-3{beta} phosphorylated S and T residues in NICD S/T-P-S/T domains. These results suggest that the novel S/T-P-S/T domain, phosphorylated by GSK-3{beta} is also involved in the nuclear localization of NICD as well as classical NLS.

China's approach to nuclear safety — From the perspective of policy and institutional system

International Nuclear Information System (INIS)

Mu, Ruimin; Zuo, Jian; Yuan, Xueliang

2015-01-01

Nuclear energy plays an important role in the energy sector in the world. It has achieved a rapid development during the past six decades and contributes to over 11% of the world's electricity supply. On the other side, nuclear accidents have triggered substantial debates with a growing public concern on nuclear facilities. Followed by the Fukushima nuclear accident, some developed countries decided to shut down the existing nuclear power plants or to abandon plans to build new ones. Given this background, accelerating the development of nuclear power on the basis of safety in China will make it a bellwether for other countries. China assigns the top priority to the nuclear safety in nuclear energy development and has maintained a good record in this field. The policy and institutional system provide the necessary guarantee for the nuclear energy development and safety management. Furthermore, China's approach to nuclear safety provides a benchmark for the safe development and utilization of nuclear power. This research draws an overall picture of the nuclear energy development and nuclear safety in China from the policy and institutional perspective. - Highlights: • China's Approach to Nuclear Safety. • Policy and Institutional System for Nuclear Energy Development. • A Benchmark for the Peaceful and Safe Utilization of Nuclear Power. • Further Efforts for Specific Laws and Administrative System

Research on U.S. nuclear power plant major equipment aging

International Nuclear Information System (INIS)

Nakos, J.T.; Rosinski, S.T.

1994-01-01

The U.S. Department of Energy (DOE) and the Electric Power Research Institute (EPRI), in cooperation with nuclear power plant utilities and the Nuclear Energy Institute, have prepared equipment aging evaluations of nuclear power plant equipment for life extension considerations. Specifically, these evaluations focused on equipment considered important for plant license renewal (U.S. Code of Federal Regulations 10CFR54). open-quotes Industry Reportsclose quotes (IRs), jointly funded by DOE and EPRI, evaluated the aging of major systems, structures, and components (e.g., reactor pressure vessels, Class I structures, PWR and BWR containments, etc.) and contain a mixture of technical and licensing information. open-quotes Aging Management Guidelinesclose quotes (AMGs), funded by DOE, evaluate aging for commodity types of equipment (e.g., pumps, electrical switchgear, heat exchangers, etc.) and concentrate on technical issues only. AMGs are intended for systems engineers and plant maintenance staff. A significant number of technical issues were resolved during IR interactions with the U.S. Nuclear Regulatory Commission (NRC). However, certain technical issues have not been resolved and are considered open-quotes openclose quotes. Examples include certain issues related to fatigue, neutron irradiation embrittlement, intergranular stress corrosion cracking (IGSCC) and electrical cable equipment qualification. Direct NRC interaction did not take place during preparation of individual AMGs due to their purely technical nature. The eventual use of AMGs in a future license renewal application will likely require NRC interaction at that time. With a few noted exceptions, the AMG process indicated that current aging management practices of U.S. utilities were effective in preventing age-related degradation. This paper briefly describes the IR and AMG processes and summarizes the unresolved technical issues identified through preparation of the documents

Are American utilities sorry they went nuclear

International Nuclear Information System (INIS)

Dallaire, E.E.

1981-01-01

The future of nuclear power in the U.S. will be determined in large measure by what the electric utilities decide to do. Very few electric utilities are planning to build more nuclear power plants. Most utilities feel the 12 to 14 years it takes to build a nuclear plant is simply too long, especially when construction money must be borrowed at record interest rates. Also, there are too many uncertainties regarding what an acceptable plant design is. On the other hand, these utilities also strongly believe that the U.S. needs nuclear power and that it would be imprudent for a utility to put all its energy eggs in one basket, coal

Solid Oxide Galvanic Cell to determine thermochemical data of Dy6UO12(s)

International Nuclear Information System (INIS)

Sahu, Manjulata; Dash, Smruti; Sen, B.K.; Venugopal, V.

2010-01-01

The rare earth elements such as Sm, Eu, Gd, and Dy have very high thermal neutron absorption cross sections and their oxides are utilized as burnable poisons in nuclear reactor to maintain constant reactivity of the core. These oxides form solid solution with urania as their ionic radii are within 20% of that of urania. Rare earth oxides-urania solid solutions are also beneficial in preventing oxidation of UO 2 (s). RE 6 UO I2 (s) (RE = rare earth) type of compounds are known to exist in RE-U-O system and their formation cannot be ruled out under transient conditions. The data on Gibbs energy of formation of compounds in RE-U-O system is therefore essential to predict the feasibility. Theoretically, the measurement of the e.m.f. of a suitable galvanic cell is one of the most accurate methods to obtain Gibbs energy of formation of compounds if e.m.f cell operates reversibly. In this study, the standard molar Gibbs energy of formation of Dy 6 UO I2 (s) was determined using solid oxide galvanic cell technique. The Gibbs energy of formation of Dy 6 UO 12 (s) is reported for the first time

L'energia nuclear: pot resoldre el problema de l'escalfament global?

OpenAIRE

Puig, Josep

2006-01-01

Sovint es diu que l'energia nuclear pot ser la solució pel problema de l'escalfament global: l'article presenta dades i raonaments per concloure que, si tota l'electricitat mundial fos d'origen nuclear, l'escalfament global es reduiria tan sols en un 12%. També s'analitzen els subproductes militars de la indústria de l'energia nuclear "civil" i la problemàtica dels residus radioactius de l'energia nuclear de fissió. També s'analitza l'alt grau de dificultats que presenta l'energia nuclear de ...

Five years after Fukushima, it's time to seize new nuclear opportunities

Energy Technology Data Exchange (ETDEWEB)

Shephers, John [nuclear24, Redditch (United Kingdom)

2016-05-15

In March of this year, we marked a painful chapter in the history of the world's civil nuclear energy industry as we reflected on the earthquake and tsunami that struck Japan five years ago - leading to the nuclear accident at Fukushima-Daiichi. In moving on, the nuclear industry needs to absorb the lessons learned from Fukushima and there are now clear signals for going on with nuclear.

North Korea’s 2009 Nuclear Test: Containment, Monitoring, Implications

Science.gov (United States)

2010-04-02

inspections as prima facie evidence of a violation. One generally-accepted means of evading detection of nuclear tests, especially low-yield tests...In an attempt to extend these bans to cover all nuclear tests, negotiations on the CTBT were completed in 1996. The treaty’s basic obligation is to...Verification refers to determining whether a nation is in compliance with its treaty obligations , which in this case means determining whether a suspicious

Saudi Arabia’s Nuclear Posture: Is Hedging the Future

Science.gov (United States)

2016-09-01

can mandate their states to proliferate. Autocratic leader Kim Jung-il put North Korea on a nuclear trajectory that his son readily followed. F.W. de...Klerk brought his country back from its existence as an undeclared nuclear state. Though it appears in historical examples that autocratic leaders ...systems.20 Figures such as these demonstrate the robust nature of the U.S.–Saudi military relationship. Blanchard explains, “Saudi leaders remain skeptical

The Role of License Renewal in PLiM for U.S. Nuclear Power Plants

International Nuclear Information System (INIS)

Young, G.G.

2012-01-01

At the 2nd International Symposium on Nuclear Power Plant Life Management (PLiM) in 2007, it was reported that the NRC had approved renewal of operating licenses for 48 nuclear units, which would allow operation for up to 60 years (i.e., an additional 20 years from the original 40-year license term). Of the 104 operating nuclear units in the U.S. in 2007, it was anticipated that almost 100% would eventually pursue license renewal. At that time, it was also concluded that the regulatory process was stable and predictable for license renewal, and that successful PLiM activities were helping to ensure the safety, economic, and political factors in the U.S. remained favorable for continued success with license renewal. The status of license renewal in 2012 is even better than it was in 2007. As of April 2012, the NRC has approved renewal of the operating licenses for 71 nuclear units and has applications under review for 15 more units. In addition, nuclear plant owners of at least 14 more units have announced plans to submit license renewal applications over the next few years. This brings the total of renewed licenses and announced plans for license renewal to 96% of the 104 currently operating nuclear units in the U.S. The prediction that almost 100% would eventually pursue license renewal is assured. This positive trend for long term operation of nuclear power plants in the U.S. is attributed to: (1) the success of PLiM activities in achieving an excellent safety record for the nuclear power industry and in ensuring on-going positive economics for nuclear plant operation, and (2) the stable and predictable regulatory process for license renewal. U.S. efforts are now underway to consider long term operation for more than 60 years and the process of preparing a second round of license renewals for up to 80 years of operation is likely to begin within the next few years. (author)

The nuclear materials control and accountability internal audit program at the Oak Ridge Y-12 plant

International Nuclear Information System (INIS)

Lewis, T.J.

1987-01-01

The internal audit program of the Nuclear Material Control and Accountability (NMCandA) Department at the Oak Ridge Y-12 Plant, through inventory-verification audits, inventory-observation audits, procedures audits, and records audits, evaluates the adequacy of material accounting and control systems and procedures throughout the Plant; appraises and verifies the accuracy and reliability of accountability records and reports; assures the consistent application of generally accepted accounting principles in accounting for nuclear materials; and assures compliance with the Department of Energy (DOE) and NMCandA procedures and requirements. The internal audit program has significantly strengthened the control and accountability of nuclear materials through improving the system of internal control over nuclear materials, increasing the awareness of materials control and accountability concerns within the Plant's material balance areas (MBAs), strengthening the existence of audit trails within the overall accounting system for nuclear materials, improving the accuracy and timeliness of data submitted to the nuclear materials accountability system, auditing the NMCandA accounting system to ensure its accuracy and reliability, and ensuring that all components of that system (general ledgers, subsidiary ledgers, inventory listings, etc.) are in agreement among themselves

Y-12 defense programs. Nuclear Packaging Systems testing capabilities

International Nuclear Information System (INIS)

1995-06-01

The Nuclear Packaging Systems (NPS) Department can manage/accomplish any packaging task. The NPS organization is responsible for managing the design, testing, certification, procurement, operation, refurbishment, maintenance, and disposal of packaging used to transport radioactive materials, other hazardous materials, and general cargoes on public roads and within the Oak Ridge Y-12 Plant. Additionally, the NPS Department has developed a Quality Assurance plan for all packaging, design and procurement of nonweapon shipping containers for radioactive materials, and design and procurement of performance-oriented packaging for hazardous materials. Further, the NPS Department is responsible for preparation and submittal of Safety Analysis Reports for Packaging (SARP). The NPS Department coordinates shipping container procurement and safety certification activities that have lead-times of up to two years. A Packaging Testing Capabilities Table at the Oak Ridge complex is included as a table

The Swedish Nuclear Power Inspectorate's evaluation of SKB's RD and D Program 98. Review report

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-04-01

that the final disposal system is not irrevocable, SKB now uses the term deep disposal. However, the term used in the legislation is final disposal. Regardless of which term is used, different degrees of retrievability can be discussed. SKI has distributed RDandD Programme 98 to sixty-three reviewing bodies for comment. Forty-five responses were received. The reviewing bodies include universities and institutes of technology, local safety committees, municipalities hosting nuclear facilities and municipalities participating in feasibility studies as well as many authorities such as county administrative boards, the Swedish Environmental Protection Agency, the Swedish Board of Housing, Building and Planning and SSI. The comments of the reviewing bodies mainly focus on the decision-making process, including issues relating to method selection and site selection and, in particular, on the selection of sites for site investigation. Several reviewing bodies, particularly universities and institutes of technology, have also submitted comments of a more technical/scientific nature. SKI's evaluation has focused on determining whether SKB's programme can be considered to fulfil the requirements stipulated in the Act on Nuclear Activities that such a programme should be able to result in the implementation of solutions for the final disposal of the spent nuclear fuel from the Swedish nuclear power programme. Furthermore, SKI's evaluation has focused on the conditions that SKI considers should apply to SKB's future work.

The Coulomb-nuclear force interference in the system 32S + 60Ni

International Nuclear Information System (INIS)

Dannhaeuser, G.

1980-01-01

For the reaction 60 Ni( 32 S, 32 S*) 60 Ni* using particle-γ-coincidences the excitation functions of 32 S(2 + 1 ) and 60 Ni(2 + 1 ) for projectile energies of 70-100 MeV as well as with Si single counters the angular distribution of the elastically and inelastically scattered 32 S ions for incident energies of 90, 95, and 100 MeV were measured. A comparison of the measurements with the results of different computer codes led to following results: 1.) At the determination of the static quadrupole moment Q 2 of 32 S using the reorientation effect the influence of the nuclear force can be neglected for projectile energies Esub(P) 32 S the value Q 2 = -0.18 +- 0.04 eb was found. (Hereby destructive interference with the virtual excitation of the 2 + 2 -state is assumed). 3.) For projectile energies Esub(P) >= 72 MeV at which the excitation by nuclear forces was small against the Coulomb excitation, an evaluation of the excitation function of 32 S(2 + 1 ) by the semiclassical code NCL, which regards the influence of the nuclear interaction approximatively, yielded values for the static quadrupole moment, which agree within the measurement errors with the above value. 4.) For the quantitative analysis of the measured angular distributions a quantum mechanical CC-code was required. 5.) Using the semiclassical CC-code NCL an illustrative and detailed interpretation of the excitation functions of 32 S(2 + 1 ) and 60 Ni(2 + 1 ) could be given. 6.) The code NCL allows the study of the influence of the Coulomb-nuclear force interference on the temporal behaviour of the excitation process. 7.) Using the code NCL the angular distribution of the decay γ quanta for a fixed particle-scattering angle theta approx. 0 in dependence on the incident energy was calculated. (orig.) [de

U.S. Nuclear Policy, Strategy, and Force Structure: Insights and Issues from the 1994, 2001, and 2010 Nuclear Posture Reviews

Science.gov (United States)

2014-09-01

community.”251 Senator Jeff Sessions, in the April 17, 2013 Hearing to Receive Testimony on Nuclear Forces and Policies, expressed concern that allies...Sagan’s NFU argument, Timothy Fischer , in a U.S. Army War College study from 2012, countered that the United States should retain a policy of possible...nuclear response to WMD because of the important role of ambiguity in national security policy flexibility and deterrence. Fischer recommended that the

Pressure broadening and frequency shift of the 5S1/2 → 5D5/2 and 5S1/2 → 7S1/2 two photon transitions in 85Rb by the noble gases and N2

International Nuclear Information System (INIS)

Zameroski, Nathan D; Hager, Gordon D; Erickson, Christopher J; Burke, John H

2014-01-01

Doppler free two photon absorption spectroscopy was employed to measure the pressure broadening and frequency shift rates of the 5S 1/2 (F = 3) → 5D 5/2 (F = 5, 4, 3, 2, 1) (778.105 nm) and the 5S 1/2 (F = 2) → 7S 1/2 (F = 2) (760.126 nm) two photon transitions in 85 Rb by the noble gases and N 2 . To our knowledge, these rates are reported on for the first time. The self-broadening and shift rate of the 5S 1/2 (F = 3) → 5D 5/2 (F = 5, 4, 3, 2, 1) transition and self -broadening rate of the 5S 1/2 (F = 2) → 7S 1/2 (F = 2) transition were also measured. The temperature dependence of the self-frequency shift (Rb-Rb collisions) of these transitions is presented. Helium diffusion rates through Quartz and Pyrex cells are also calculated and the implication of helium diffusion through glass vapor cells is discussed in regards to atomic frequency standards based on these transitions. Experimental pressure broadening and shift rates are compared to theoretically calculated rates assuming a 6, 8 or 6, 8, 10 difference potential and pseudo potential model. Reasonable agreement is achieved between experimental and theoretical values. (paper)

Study of the Nuclear Transparency in $\\alpha$ + A Reactions at Energies $\\geq$ 12 GeV/nucleon

CERN Multimedia

2002-01-01

The question about transparency is crucial for heavy ion reaction studies. If the transparency is low at 10-15 GeV per nucleon then very large baryon densities can be achieved in this energy range, maybe enough to produce quark-gluon plasma in U+U collisions. We propose to measure, event by event, pseudo-rapidity and multiplicity distributions of singly charged relativistic particles (@b~$>$~0.7) globally and in selected regions of rapidity as well as multiplicities of recoiling protons (30-400~Me charged nuclear fragments. These studies will explore general features of @a+A reactions at energies @$>$~12~GeV/nucleon. The main goal of the experiment is to measure the transparency of nuclear matter in this energy range. The detector will be nuclear emulsion.

Action en santé mentale au travail et syndicalisme québécois : l'expérience de représentants syndicaux

OpenAIRE

Deslauriers, Jean-Simon

2016-01-01

Dans certains milieux syndicaux québécois, des initiatives porteuses destinées à prévenir les problèmes de santé mentale au travail ont vu le jour. Des représentants syndicaux pionniers ont mis en place des structures d’entraide opérantes, obtenu des jurisprudences importantes et développé des approches innovantes pour corriger ou bonifier l’organisation du travail, et ce depuis plus de trois décennies. Alors que la montée de l’idéologie néolibérale et les principes d’organisation du travail ...

The Hidden Diversity of Zanclea Associated with Scleractinians Revealed by Molecular Data.

Directory of Open Access Journals (Sweden)

Simone Montano

Full Text Available Scleractinian reef corals have recently been acknowledged as the most numerous host group found in association with hydroids belonging to the Zanclea genus. However, knowledge of the molecular phylogenetic relationships among Zanclea species associated with scleractinians is just beginning. This study, using the nuclear 28S rDNA region and the fast-evolving mitochondrial 16S rRNA and COI genes, provides the most comprehensive phylogenetic reconstruction of the genus Zanclea with a particular focus on the genetic diversity among Zanclea specimens associated with 13 scleractinian genera. The monophyly of Zanclea associated with scleractinians was strongly supported in all nuclear and mitochondrial phylogenetic reconstructions. Furthermore, a combined mitochondrial 16S and COI phylogenetic tree revealed a multitude of hidden molecular lineages within this group (Clades I, II, III, V, VI, VII, and VIII, suggesting the existence of both host-generalist and genus-specific lineages of Zanclea associated with scleractinians. In addition to Z. gallii living in association with the genus Acropora, we discovered four well-supported lineages (Clades I, II, III, and VII, each one forming a strict association with a single scleractinian genus, including sequences of Zanclea associated with Montipora from two geographically separated areas (Maldives and Taiwan. Two host-generalist Zanclea lineages were also observed, and one of them was formed by Zanclea specimens symbiotic with seven scleractinian genera (Clade VIII. We also found that the COI gene allows the recognition of separated hidden lineages in agreement with the commonly recommended mitochondrial 16S as a DNA barcoding gene for Hydrozoa and shows reasonable potential for phylogenetic and evolutionary analyses in the genus Zanclea. Finally, as no DNA sequences are available for the majority of the nominal Zanclea species known, we note that they will be necessary to elucidate the diversity of the

The Hidden Diversity of Zanclea Associated with Scleractinians Revealed by Molecular Data

KAUST Repository

Montano, Simone

2015-07-24

Scleractinian reef corals have recently been acknowledged as the most numerous host group found in association with hydroids belonging to the Zanclea genus. However, knowledge of the molecular phylogenetic relationships among Zanclea species associated with scleractinians is just beginning. This study, using the nuclear 28S rDNA region and the fast-evolving mitochondrial 16S rRNA and COI genes, provides the most comprehensive phylogenetic reconstruction of the genus Zanclea with a particular focus on the genetic diversity among Zanclea specimens associated with 13 scleractinian genera. The monophyly of Zanclea associated with scleractinians was strongly supported in all nuclear and mitochondrial phylogenetic reconstructions. Furthermore, a combined mitochondrial 16S and COI phylogenetic tree revealed a multitude of hidden molecular lineages within this group (Clades I, II, III, V, VI, VII, and VIII), suggesting the existence of both host-generalist and genus-specific lineages of Zanclea associated with scleractinians. In addition to Z. gallii living in association with the genus Acropora, we discovered four well-supported lineages (Clades I, II, III, and VII), each one forming a strict association with a single scleractinian genus, including sequences of Zanclea associated with Montipora from two geographically separated areas (Maldives and Taiwan). Two host-generalist Zanclea lineages were also observed, and one of them was formed by Zanclea specimens symbiotic with seven scleractinian genera (Clade VIII). We also found that the COI gene allows the recognition of separated hidden lineages in agreement with the commonly recommended mitochondrial 16S as a DNA barcoding gene for Hydrozoa and shows reasonable potential for phylogenetic and evolutionary analyses in the genus Zanclea. Finally, as no DNA sequences are available for the majority of the nominal Zanclea species known, we note that they will be necessary to elucidate the diversity of the Zanclea

Westinghouse calls for rethink on Europe's treatment of nuclear

Energy Technology Data Exchange (ETDEWEB)

Kraev, Kamen [NucNet The Independent Global Nuclear News Agency, Brussels (Belgium)

2017-12-15

US-based nuclear equipment manufacturer Westinghouse Electric Company has called on European Union legislators to adopt a technology-neutral approach when discussing the future of the bloc's low-carbon energy policies. In its 'Clean Energy for All Europeans' legislative package, released in November 2016, the European Commission made no mention of nuclear energy, said Michael Kirst, Westinghouse's vice-president of strategy for the Europe, Middle East and Africa (EMEA) region at a media briefing in Brussels. He said the package did not offer ''a real investment signal'' to developers.

Nuclear material management: challenges and prospects

International Nuclear Information System (INIS)

Rieu, J.; Besnainou, J.; Leboucher, I.; Chiguer, M.; Capus, G.; Greneche, D.; Durret, L.F.; Carbonnier, J.L.; Delpech, M.; Loaec, Ch.; Devezeaux de Lavergne, J.G.; Granger, S.; Devid, S.; Bidaud, A.; Jalouneix, J.; Toubon, H.; Pochon, E.; Bariteau, J.P.; Bernard, P.; Krellmann, J.; Sicard, B.

2008-01-01

The articles in this dossier were derived from the papers of the yearly S.F.E.N. convention, which took place in Paris, 12-13 March 2008. They deal with the new challenges and prospects in the field of nuclear material management, throughout the nuclear whole fuel cycle, namely: the institutional frame of nuclear materials management, the recycling, the uranium market, the enrichment market, the different scenarios for the management of civil nuclear materials, the technical possibilities of spent fuels utilization, the option of thorium, the convention on the physical protection of nuclear materials and installations, the characterisation of nuclear materials by nondestructive nuclear measurements, the proliferation from civil installations, the use of plutonium ( from military origin) and the international agreements. (N.C.)

IPEN's Nuclear Physics and Chemistry Department - Progress report - 1995-1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-07-01

The biannual progress report of 1995-1996 of IPEN's Nuclear Physics and Chemistry Department - Brazilian organization - introduces the next main topics: neutron activation and radiochemical analysis; nuclear structure and reactions; neutron diffraction; hyperfine interactions; applied physics and instrumentation; publications; academic activities; services; and personnel.

COOLING WATER ISSUES AND OPPORTUNITIES AT U.S. NUCLEAR POWER PLANTS

Energy Technology Data Exchange (ETDEWEB)

Gary Vine

2010-12-01

This report has been prepared for the Department of Energy, Office of Nuclear Energy (DOE-NE), for the purpose of providing a status report on the challenges and opportunities facing the U.S. commercial nuclear energy industry in the area of plant cooling water supply. The report was prompted in part by recent Second Circuit and Supreme Court decisions regarding cooling water system designs at existing thermo-electric power generating facilities in the U.S. (primarily fossil and nuclear plants). At issue in the courts have been Environmental Protection Agency regulations that define what constitutes “Best Technology Available” for intake structures that withdraw cooling water that is used to transfer and reject heat from the plant’s steam turbine via cooling water systems, while minimizing environmental impacts on aquatic life in nearby water bodies used to supply that cooling water. The report was also prompted by a growing recognition that cooling water availability and societal use conflicts are emerging as strategic energy and environmental issues, and that research and development (R&D) solutions to emerging water shortage issues are needed. In particular, cooling water availability is an important consideration in siting decisions for new nuclear power plants, and is an under-acknowledged issue in evaluating the pros and cons of retrofitting cooling towers at existing nuclear plants. Because of the significant ongoing research on water issues already being performed by industry, the national laboratories and other entities, this report relies heavily on ongoing work. In particular, this report has relied on collaboration with the Electric Power Research Institute (EPRI), including its recent work in the area of EPA regulations governing intake structures in thermoelectric cooling water systems.

Asymptotic normalization coefficients, nuclear vertex constants and nuclear astrophysics problems

International Nuclear Information System (INIS)

Yarmukhamedov, R.; Artemov, S.V.; Igamov, S.B.; Burtebaev, N.; Peterson, R.J.

2007-01-01

Full text: We will review the results of a comprehensive analysis of the experimental astrophysical S- factors S(E) for the t(α, γ ) 7 Li, 3 He(α, γ) 7 Be, 7 Be(p, γ) 8 B, 12 C(p , γ) 13 N and 13 C(p,γ) 14 N reactions at extremely low energies, performed within a three-sided collaboration (Uzbekistan-Kazakhstan-USA). In the analysis, the new experimental data for the 12 C(p, γ) 13 N reaction are also included, as measured with the accelerator UKP-2-1 at the Institute of Nuclear Physics in Kazakhstan. The analysis is carried out within the framework of a new two-body potential approach and the R-matrix method, taking into account information about the asymptotic normalization coefficient (ANC) (or the respective nuclear vertex constant for virtual decay of the residual nuclei into two fragments of the initial states of the aforesaid reactions, which belong to the fundamental nuclear constants). Nowadays ANC's are obtained from analysis of peripheral one nucleon transfer reactions by method combining dispersion theory and DWBA (CM). It is shown that ANC can be also reliably obtained from analysis of proton capture reactions at astrophysical energies by new modified two-body potential method where the CM is used. A comparative analysis of the results obtained by different authors in the framework of different methods is also done

Radiation shielding and criticality safety assessment for KN-12 spent nuclear fuel transport cask

Energy Technology Data Exchange (ETDEWEB)

Kim, Jong Kyung; Shin, Chang Ho; Kim, Gi Hwan [Hanyang Univ., Seoul (Korea, Republic of)

2001-08-15

Because SNFs involve TRU (Transuranium), fission products, and fissile materials, they are highly radioactive and also have a possibility to be critical. Therefore, radiation shielding and criticality safety for transport casks containing the SNFs should be guaranteed through reliable valuation procedure. IAEA safety standard series No ST-1 recommends regulation for safe transportation of the SNFs by transport casks, and United States is carrying out it according to the regulation guide, 10 CFR parts 71 and 72. Present research objective is to evaluate the KN-12 spent nuclear fuel transport cask that is designed for transportation of up to 12 assemblies and is standby status for being licensed in accordance with Korea Atomic Energy Act. Both radiation shielding and criticality analysis using the accurate Monte Carlo transport code, MCNP-4B are carried out for the KN-12 SNF cask as a benchmark calculation. Source terms for radiation shielding calculation are obtained using ORIGEN-S computer code. In this work, for normal transport conditions, the results from MCNP-4B shows the maximum dose rate of 0.557 mSv/hr at the side surface. And the maximum dose rate of 0.0871 mSv/hr was resulted at the 2 m distance from the cask. The level of calculated dose rate is 27.9% of the limit at the cask surface, 87.1% at 2 m from the cask surface for normal transport condition. For hypothetical accident conditions, the maximum rate of 2.5144 mSv/hr was resulted at the 1 m distance from the cask and this level is 25.1% of the limit for hypothetical accident conditions. In criticality calculations using MCNP-4B, the k{sub eff} values yielded for 5.0 w/o U-235 enriched fresh fuel are 0.92098 {+-} 0.00065. This result confirms subcritical condition of the KN-12 SNF cask and gives 96.95% of recommendations for criticality safety evaluation by US NRC these results will be useful as a basis for approval for the KN-12 SNF cask.

First identification of eggs of the Asian fish tapeworm Bothriocephalus acheilognathi (Cestoda: Bothriocephalidea) in human stool

Czech Academy of Sciences Publication Activity Database

Yera, H.; Kuchta, Roman; Brabec, Jan; Peyron, F.; Dupouy-Camet, J.

2013-01-01

Roč. 62, č. 3 (2013), s. 268-271 ISSN 1383-5769 R&D Projects: GA ČR GBP505/12/G112; GA ČR GAP506/12/1632 Institutional support: RVO:60077344 Keywords : COI * Diphyllobothrium * French Guiana * Man * Molecular identification * rDNA Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.111, year: 2013

Could persistency of current of injury forecast successful active-fixation pacing lead implantation?

Science.gov (United States)

Shali, Shalaimaiti; Su, Yangang; Qin, Shengmei; Ge, Junbo

2018-05-01

Presence of adequate current of injury (COI) was recognized as a sign of favorable pacemaker lead outcome. Little is known regarding the value of its dynamic behavior. We sought to test whether persistency of COI could predict active-fixation pacing lead performance. COI was monitored up to 10min after right ventricular (RV) pacing electrode fixation. COI persistency was defined as the percentage of COI magnitude relative to its initial measurement. An unacceptable pacing threshold (≥1.0V in acute evaluation or ≥2.0V over 2-year follow-up) with or without lead dislodgement was considered as lead failure. Lead implantation was attempted for 217 times in 174 patients (age 66.3±7.8years, 78 female). Acute lead failures occurred 43 times. Independent predictors of acute lead failure were RV enlargement (odds ratio [OR] 1.23, 95% confidential interval [CI] 1.11-2.04, P=0.033), absence of COI (OR 3.13, 95%CI 2.08-9.09, P=0.027), and COI persistency at 5min (OR 0.32, 95%CI 0.20-0.69, P=0.001) and 10min (OR 0.41, 95%CI 0.13-0.77, P=0.001). The optimal cutoffs were COI 5min persistency ≥50% (sensitivity 81.4%; specificity 81.9%) and COI 10min persistency ≥20% (sensitivity 86%; specificity 88.6%). There were 12 lead failures during 24.0±6.4months of follow-up. Patients with COI 5min persistency ≥50% had higher event-free survival compared to those with COI 5min persistency <50% (hazard ratio 3.54, 95% CI 1.04-12.06, P=0.043). COI persistency appears to be a valuable indicator for both acute and long-term outcome of active-fixation pacemaker leads. A precipitous decline in COI may require more attention to make sure of the lead performance. Copyright © 2018 Elsevier Ireland Ltd. All rights reserved.

ELECNUC. Nuclear power plants in the world - 2014 edition. Status on 12-31-2013, Draft using the IAEA's PRIS database and specific I-tese studies

International Nuclear Information System (INIS)

2014-01-01

Japan situation has not significantly changed since 2012, almost all its nuclear power plants are still stopped. The process for restarting 48 of them is under way but expected to take some years. As last year no order was registered, but 2013 met an important number of building starts concerning 10 new PWR (11.3 GWe): 1 - Belarus: First building site in eastern Europe (excluded Russia) for more than 25 years. 2 - USA: Four PWR units (4.5 GWe) that represent the first new buildings in this country since 1977. 3 - China: Three new PWR, that leads to a total of 27 plants under construction in this country. 4 - United Arab Emirates and South Korea: The sister-ships of Barakah-2 and Shin-Hanul-2 started right after the No.1 units in 2012. These 10 new plants are all PWR units, which is coherent with the worldwide situation of 58 PWR constructions for only 4 PHWR in India (and 4 BWR - 2 in Japan and 2 in Taiwan - all delayed for different reasons). Worldwide capacity balance Despite the commercial start of 3 GWe (2 PWR in China, 1 in Iran), the planned shutdown of 6 units (5.4 GWe: Fukushima-Daishi 5 and 6 in Japan and 4 PWR in USA) leads to a decrease of -2.4 GWe of the nuclear capacity. Thanks to a better average load factor the overall nuclear electricity production still increases of 13 TWh. But as 4.1 GWe (3 PWR in China, 1 in India) were connected to the grid and the constructions represent more than 50 units with about 10 annual commercial operations for the next four years, this loss of capacity should be exceptional. Contents: 1) 2013 highlights; 2) Main characteristics of reactor types; 3) Map of the French nuclear power plants on 01/01/2013; 4) Worldwide status of nuclear power plants (12/31/2013); 5) Units distributed by countries; 6) Nuclear power plants connected to the Grid- by reactor type groups (12/31/2013); 7) Nuclear power plants under construction on 2013; 8) Evolution of nuclear power plants capacities connected to the grid; 9) First electric

U.S. nuclear policy, strategy, and force structure: insights and issues from the 1994, 2001, and 2010 nuclear posture reviews

OpenAIRE

Lyons, Marco J.

2014-01-01

Approved for public release; distribution is unlimited This thesis examines the main decisions taken in the 1994, 2001, and 2010 Nuclear Posture Reviews regarding U.S. nuclear capabilities and declaratory strategy, and the policy debates that followed the publication of each NPR, focusing on deterrence and other objectives of U.S. national security strategy. It analyzes and compares the post–Cold War NPRs to understand how each administration attempted to shape and direct policy, and how k...

Nuclear Energy Infrastructure Database Description and User's Manual

International Nuclear Information System (INIS)

Heidrich, Brenden

2015-01-01

In 2014, the Deputy Assistant Secretary for Science and Technology Innovation initiated the Nuclear Energy (NE)–Infrastructure Management Project by tasking the Nuclear Science User Facilities, formerly the Advanced Test Reactor National Scientific User Facility, to create a searchable and interactive database of all pertinent NE-supported and -related infrastructure. This database, known as the Nuclear Energy Infrastructure Database (NEID), is used for analyses to establish needs, redundancies, efficiencies, distributions, etc., to best understand the utility of NE's infrastructure and inform the content of infrastructure calls. The Nuclear Science User Facilities developed the database by utilizing data and policy direction from a variety of reports from the U.S. Department of Energy, the National Research Council, the International Atomic Energy Agency, and various other federal and civilian resources. The NEID currently contains data on 802 research and development instruments housed in 377 facilities at 84 institutions in the United States and abroad. The effort to maintain and expand the database is ongoing. Detailed information on many facilities must be gathered from associated institutions and added to complete the database. The data must be validated and kept current to capture facility and instrumentation status as well as to cover new acquisitions and retirements. This document provides a short tutorial on the navigation of the NEID web portal at NSUF-Infrastructure.INL.gov.

Reviews of the Comprehensive Nuclear-Test-Ban Treaty and U.S. security

Science.gov (United States)

Jeanloz, Raymond

2017-11-01

Reviews of the Comprehensive Nuclear-Test-Ban Treaty (CTBT) by the National Academy of Sciences concluded that the United States has the technical expertise and physical means to i) maintain a safe, secure and reliable nuclear-weapons stockpile without nuclear-explosion testing, and ii) effectively monitor global compliance once the Treaty enters into force. Moreover, the CTBT is judged to help constrain proliferation of nuclear-weapons technology, so it is considered favorable to U.S. security. Review of developments since the studies were published, in 2002 and 2012, show that the study conclusions remain valid and that technical capabilities are better than anticipated.

Automated nuclear materials accounting

International Nuclear Information System (INIS)

Pacak, P.; Moravec, J.

1982-01-01

An automated state system of accounting for nuclear materials data was established in Czechoslovakia in 1979. A file was compiled of 12 programs in the PL/1 language. The file is divided into four groups according to logical associations, namely programs for data input and checking, programs for handling the basic data file, programs for report outputs in the form of worksheets and magnetic tape records, and programs for book inventory listing, document inventory handling and materials balance listing. A similar automated system of nuclear fuel inventory for a light water reactor was introduced for internal purposes in the Institute of Nuclear Research (UJV). (H.S.)

The Impact of Financial Conflicts of Interest in Plastic Surgery: Are They All Created Equal?

Science.gov (United States)

Lopez, Joseph; Juan, Ilona; Wu, Adela; Samaha, Georges; Cho, Brian; Luck, J D; Soni, Ashwin; Milton, Jacqueline; May, James W; Tufaro, Anthony P; Dorafshar, Amir H

2016-08-01

Recently, several studies have demonstrated that articles that disclose conflicts of interests (COI) are associated with publication of positive results. The purpose of this study was to learn more about the different types of COI as they relate to the general topic of COI in plastic surgery. Specifically, we aimed to examine whether different types of COI are more likely than others to be associated with the presentation of positive findings. We reviewed all original articles in Annals of Plastic Surgery, Journal of Plastic, Reconstructive, and Aesthetic Surgery, and Plastic & Reconstructive Surgery from January 1, 2012, to December 31, 2013. All scientific articles were analyzed, and several article characteristics were extracted. Disclosed COI were categorized into the following categories: consultant/employee, royalties/stock options, and research support. The findings reported in each article abstract were blindly graded as reporting a positive, negative, neutral, or not applicable result. A multivariable analysis was performed to determine whether an association existed between certain types of COI and publication of positive conclusions. A total of 3124 articles were identified of which 1185 fulfilled the inclusion criteria. Financial COI were reported in 153 studies (12.9%). The most common type of COI was "research support" (7.3%), whereas the least common was "royalties/stock options" (1.2%). Rates of different types of COI varied significantly by plastic surgery subspecialty field (P reported COI are uncommon in plastic surgery research. Our results provide evidence that certain types of financial COI are more likely than others to be associated with the presentation of positive findings. This analysis suggests that certain investigators may be more biased, consciously or unconsciously, by the type of financial benefit offered by industry.

Discrimination of DPRK M5.1 February 12th, 2013 Earthquake as Nuclear Test Using Analysis of Magnitude, Rupture Duration and Ratio of Seismic Energy and Moment

Science.gov (United States)

Salomo Sianipar, Dimas; Subakti, Hendri; Pribadi, Sugeng

2015-04-01

On February 12th, 2013 morning at 02:57 UTC, there had been an earthquake with its epicenter in the region of North Korea precisely around Sungjibaegam Mountains. Monitoring stations of the Preparatory Commission for the Comprehensive Nuclear Test-Ban Treaty Organization (CTBTO) and some other seismic network detected this shallow seismic event. Analyzing seismograms recorded after this event can discriminate between a natural earthquake or an explosion. Zhao et. al. (2014) have been successfully discriminate this seismic event of North Korea nuclear test 2013 from ordinary earthquakes based on network P/S spectral ratios using broadband regional seismic data recorded in China, South Korea and Japan. The P/S-type spectral ratios were powerful discriminants to separate explosions from earthquake (Zhao et. al., 2014). Pribadi et. al. (2014) have characterized 27 earthquake-generated tsunamis (tsunamigenic earthquake or tsunami earthquake) from 1991 to 2012 in Indonesia using W-phase inversion analysis, the ratio between the seismic energy (E) and the seismic moment (Mo), the moment magnitude (Mw), the rupture duration (To) and the distance of the hypocenter to the trench. Some of this method was also used by us to characterize the nuclear test earthquake. We discriminate this DPRK M5.1 February 12th, 2013 earthquake from a natural earthquake using analysis magnitude mb, ms and mw, ratio of seismic energy and moment and rupture duration. We used the waveform data of the seismicity on the scope region in radius 5 degrees from the DPRK M5.1 February 12th, 2013 epicenter 41.29, 129.07 (Zhang and Wen, 2013) from 2006 to 2014 with magnitude M ≥ 4.0. We conclude that this earthquake was a shallow seismic event with explosion characteristics and can be discriminate from a natural or tectonic earthquake. Keywords: North Korean nuclear test, magnitude mb, ms, mw, ratio between seismic energy and moment, ruptures duration

Birth and early history of nuclear power

International Nuclear Information System (INIS)

Kenton, J.E.

1978-01-01

The history of nuclear generation of electric power is traced from Sir Ernest Rutherford's first pessimistic assessment in 1933 to the present time, when 12% of U.S. electricity comes from nuclear plants. The U.S. Navy is credited with being the first to see the potential for nuclear power reactors for submarine propulsion. The author relates the story of the Manhattan Engineering District during World War II and traces the nuclear submarine development as it paralleled postwar civilian power programs from the first light water reactors to the present controversy over the breeder reactor. The momentum of technology development is seen to have slowed, possibly because the 1955 success of the USS Nautilus prompted world acceptance of the LWR as the dominant power reactor

The nuclear technology development program in the U.S.S.R

International Nuclear Information System (INIS)

Lukonin, N.F.

1987-01-01

The trend of strategy on the nuclear power generation in USSR is not changed in spite of the accident in Chernobyl Nuclear Power Station. In 1986, the electric power generated by nuclear power generation was 162 billion kWh, and the heat supply by nuclear energy was 29 million Gcal. The development of nuclear power generation in USSR for 30 years proved that the atomic energy is technically omnipotent, and the economical substitution of the demand of fossil fuel with nuclear fuel is possible. As of January 1, 1987, 17 nuclear power stations were in operation in USSR, and the total power output was 31,000 MW. The share of nuclear power generation in the total electric power generation was 1/9. 11 nuclear power stations are under construction. The accelerating development of nuclear power generation is the base of meeting the electric power demand in the European region of USSR together with the power transmission from the eastern region. The nuclear power generation in USSR is based on two types of nuclear reactors, that is, water-water type VVER and water-graphite type RBMK. The accident in Chernobyl Nuclear Power Station and the situation thereafter are reported. The development of nuclear power generation in future is discussed. (Kako, I.)

Nuclear cluster strategy Carolinas - Ontario - Saskatchewan

International Nuclear Information System (INIS)

Oberth, R.

2012-01-01

Organization of Candu Industries (OCI) is an industry association representing the interests of 170 private sector suppliers of products and services to the Canadian and offshore nuclear industries. OCI member companies, mainly in Ontario, employ over 30,000 highly specialized workers with over 12,000 working in nuclear area. OCI's objectives are to sustain the domestic nuclear program by building support among political leaders, the public and local communities, assist OCI member companies in becoming the preferred suppliers for domestic nuclear projects (competitive), assist OCI member companies in international nuclear markets - trade missions and vendor workshops. OCI is at the heart of an 'Ontario nuclear cluster'. The Carolinas have shown what can be achieved when industry, academia, S&T centers and governments collaborate with a shared vision to achieve a common goals. Ontario has the assets to become a stronger center for nuclear excellence. OCI is working to bring the pieces together. Saskatchewan has the assets to become a center of excellence in Small Modular Reactors (SMR) by licensing and constructing the first SMR in Canada.

The Swedish Nuclear Power Inspectorate`s evaluation of SKB`s RD and D Program 98. Summary and conclusions

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-04-01

Compared to previous programmes, RD and D Programme 98 is focused to a greater extent on method and site selection and on issues relating to the decision-making process. This is natural, since the programme is now approaching the stage where vital decisions will have to be made. The RD and D Programme 98 report is supplemented by a background report `Detailed Programme for Research and Development 1999-2004` as well as a number of main references `System Reporting`, `Alternative methods`, `Criteria for Site Evaluation` and the `North-South/Coast-Interior` report. In addition, a number of references are available in the form of county-specific general siting studies, feasibility studies etc. SKI has distributed RD and D Programme 98 to sixty-three reviewing bodies for comment. The reviewing bodies include universities and institutes of technology, local safety committees, municipalities hosting nuclear facilities and municipalities participating in feasibility studies as well as many authorities. The comments of the reviewing bodies mainly focused on the decision-making process, including issues relating to method selection and site selection and, in particular, on the selection of sites for site investigation. Several reviewing bodies, particularly universities and institutes of technology, have also submitted comments of a more technical-scientific nature. SKI`s evaluation has focused on determining whether SKB`s programme can be considered to fulfil the requirements stipulated in the Act on Nuclear Activities that such a programme should be able to result in the implementation of solutions for the final disposal of the spent nuclear fuel from the Swedish nuclear power programme. Furthermore, SKI`s evaluation has also focused on the conditions that SKI considers should apply to SKB`s future work. Specific comments are made for the following areas: Decision-making process, Method selection and system analysis, Siting, Technical development, Safety assessments

Sub-Coulomb α Transfers on C12 and the C12(α, γ)O16 S Factor

International Nuclear Information System (INIS)

Brune, C. R.; Geist, W. H.; Kavanagh, R. W.; Veal, K. D.

1999-01-01

The 12 C( α, γ) 16 O reaction is crucial for the understanding of He burning in massive stars, but the low-energy cross section is highly uncertain. To address this problem we have measured at sub-Coulomb energies total cross sections for the 12 C( 6 Li, d) 16 O and 12 C( 7 Li, t) 16 O reactions to the bound 2 + and 1 - states of 16 O . The data are analyzed to obtain the reduced α widths of these states. Together with capture and phase-shift data, these results provide for a more accurate determination of the low-energy 12C(α, γ) 16 O S factor: S E1 (0.3 MeV) =101±17 keV b and S E2 (0.3 MeV) =42 +16 -23 keV b for the E1 and E2 multipole components of the reaction. (c) 1999 The American Physical Society

Why are U.S. nuclear weapon modernization efforts controversial?

Science.gov (United States)

Acton, James

2016-03-01

U.S. nuclear weapon modernization programs are focused on extending the lives of existing warheads and developing new delivery vehicles to replace ageing bombers, intercontinental ballistic missiles, and ballistic missile submarines. These efforts are contested and controversial. Some critics argue that they are largely unnecessary, financially wasteful and potentially destabilizing. Other critics posit that they do not go far enough and that nuclear weapons with new military capabilities are required. At its core, this debate centers on three strategic questions. First, what roles should nuclear weapons be assigned? Second, what military capabilities do nuclear weapons need to fulfill these roles? Third, how severe are the unintended escalation risks associated with particular systems? Proponents of scaled-down modernization efforts generally argue for reducing the role of nuclear weapons but also that, even under existing policy, new military capabilities are not required. They also tend to stress the escalation risks of new--and even some existing--capabilities. Proponents of enhanced modernization efforts tend to advocate for a more expansive role for nuclear weapons in national security strategy. They also often argue that nuclear deterrence would be enhanced by lower yield weapons and/or so called bunker busters able to destroy more deeply buried targets. The debate is further fueled by technical disagreements over many aspects of ongoing and proposed modernization efforts. Some of these disagreements--such as the need for warhead life extension programs and their necessary scope--are essentially impossible to resolve at the unclassified level. By contrast, unclassified analysis can help elucidate--though not answer--other questions, such as the potential value of bunker busters.

11 CFR 100.11 - State (2 U.S.C. 431(12)).

Science.gov (United States)

2010-01-01

... 11 Federal Elections 1 2010-01-01 2010-01-01 false State (2 U.S.C. 431(12)). 100.11 Section 100.11 Federal Elections FEDERAL ELECTION COMMISSION GENERAL SCOPE AND DEFINITIONS (2 U.S.C. 431) General Definitions § 100.11 State (2 U.S.C. 431(12)). State means each State of the United States, the District of...

U.S./CIS eye joint nuclear rocket venture

Science.gov (United States)

Clark, John S.; Mcilwain, Melvin C.; Smetanikov, Vladimir; D'Yakov, Evgenij K.; Pavshuk, Vladimir A.

1993-01-01

An account is given of the significance for U.S. spacecraft development of a nuclear thermal rocket (NTR) reactor concept that has been developed in the (formerly Soviet) Commonwealth of Independent States (CIS). The CIS NTR reactor employs a hydrogen-cooled zirconium hydride moderator and ternary carbide fuels; the comparatively cool operating temperatures associated with this design promise overall robustness.

Nuclear Energy Decree of February 12, 1988

International Nuclear Information System (INIS)

1988-01-01

This decree no. 161/1988 entered into force on 1 March 1988. It was made in accordance with Section 82 of the 1987 Nuclear Energy Act and aims to define the scope of application of the Act. The Decree deals with the licensing procedure for nuclear installations and competence in this field. It also establishes exemptions to the licencing of radioactive materials and covers radioactive waste management and its financing. (NEA) [fr

The nuclear industry's plan to achieve new nuclear power plant orders in the 1990's

International Nuclear Information System (INIS)

Bayne, P.

1993-01-01

Since the Arab Oil Embargo of 1973, there has been a direct relationship between the growth in the Gross Domestic Product and the growth in the use of electricity in the United States. That close relationship between economic growth and electricity will continue. If that is true, the United States Department of Energy says this country will need between 190,000 to 275,000 megawatts of new generating capacity in the next 20 years. Electricity is one of the cleanest and most efficient uses of energy. Of all the ways to generate electricity, nuclear power plants are the cleanest, producing no air pollution and no greenhouse gases. To help supply the needed increase in electricity generating capacity, the US nuclear power industry has developed a Strategic Plan for Building New Nuclear Power Plants. The plan identified fourteen issues which must be dealt with to create the conditions under which utilities could place orders for new nuclear plants by the mid-1990's. The plan was published in November of 1990 and significant progress has been made on most of the fourteen issues. The plan and progress made are reviewed in depth

First Large-Scale DNA Barcoding Assessment of Reptiles in the Biodiversity Hotspot of Madagascar, Based on Newly Designed COI Primers

Science.gov (United States)

Nagy, Zoltán T.; Sonet, Gontran; Glaw, Frank; Vences, Miguel

2012-01-01

Background DNA barcoding of non-avian reptiles based on the cytochrome oxidase subunit I (COI) gene is still in a very early stage, mainly due to technical problems. Using a newly developed set of reptile-specific primers for COI we present the first comprehensive study targeting the entire reptile fauna of the fourth-largest island in the world, the biodiversity hotspot of Madagascar. Methodology/Principal Findings Representatives of the majority of Madagascan non-avian reptile species (including Squamata and Testudines) were sampled and successfully DNA barcoded. The new primer pair achieved a constantly high success rate (72.7–100%) for most squamates. More than 250 species of reptiles (out of the 393 described ones; representing around 64% of the known diversity of species) were barcoded. The average interspecific genetic distance within families ranged from a low of 13.4% in the Boidae to a high of 29.8% in the Gekkonidae. Using the average genetic divergence between sister species as a threshold, 41–48 new candidate (undescribed) species were identified. Simulations were used to evaluate the performance of DNA barcoding as a function of completeness of taxon sampling and fragment length. Compared with available multi-gene phylogenies, DNA barcoding correctly assigned most samples to species, genus and family with high confidence and the analysis of fewer taxa resulted in an increased number of well supported lineages. Shorter marker-lengths generally decreased the number of well supported nodes, but even mini-barcodes of 100 bp correctly assigned many samples to genus and family. Conclusions/Significance The new protocols might help to promote DNA barcoding of reptiles and the established library of reference DNA barcodes will facilitate the molecular identification of Madagascan reptiles. Our results might be useful to easily recognize undescribed diversity (i.e. novel taxa), to resolve taxonomic problems, and to monitor the international pet trade

Let's talk nuclear energy in 30 questions; Parlons nucleaire en 30 questions

Energy Technology Data Exchange (ETDEWEB)

Reuss, Paul

2012-01-11

The Fukushima catastrophe of March 11, 2011 has called into question the share of nuclear energy in France and in foreign countries. Its replacement by renewable energy sources and the safety of nuclear power plants are in the center of today's debates. But what is the reality behind the mass of contradictory information that exists on this complex topic? This book moves the question out of the media noise and supplies objective and factual information with reliable figures about the nuclear industry by answering 30 key-questions. (J.S.)

Managing Nuclear Corporate Memories: Malaysia's Contribution to INIS Development

International Nuclear Information System (INIS)

Mohd Hafizal Yusof; Habibah Adnan

2015-01-01

International Atomic Energy Agency (IAEA) is an organization under the United Nations (UN), which serves to disseminate accurate information about the nuclear matters. In accordance with its role, an International Nuclear Information System (INIS) was established in 1970 to provide opportunities for member countries under the auspices of the IAEA to share information, expertise and knowledge, particularly in the nuclear field. Malaysia became a member since 1978, and the first country's input was posted in 1980. INIS activities are supervised by liaison officers (LO) to monitor and oversee matters relating to INIS management. From 1980 until 2013, there are many developments in INIS input and variation of publication type that have been indexed. Number of input increased year by year because of enhancement of publication published and also promotional activities that have been done either in Nuclear Malaysia itself or outside the Nuclear Malaysia. This paper will elaborate efforts done by Malaysian INIS Center in promoting INIS to Nuclear Malaysia researchers and target universities library in Malaysia. (author)

Nuclear information needs for the astrophysical s-process

Energy Technology Data Exchange (ETDEWEB)

Mathews, G.J.; Howard, W.M.; Takahashi, K.; Ward, R.A.

1986-01-01

The astrophysical s-process is a sequence of neutron-capture and beta-decay reactions on a slow time scale compared to beta-decay lifetimes near the line of stability. This detailed sequence of neutron capture, continuum and bound-state beta decay, positron decay, and electron-capture reactions that comprise the s-process has been studied for a broad range of astrophysical environments. The results are then compared with the solar-system abundancies of heavy elements to determine the range of physical conditions responsible for their nucleosynthesis. The nuclear data needs are extensive but have begun to be precise enough to allow for a consistent interpretation of the astrophysical site for the s-process.

Nuclear information needs for the astrophysical s-process

Energy Technology Data Exchange (ETDEWEB)

Mathews, G.J.; Howard, W.M.; Takahashi, K.; Ward, R.A.

1985-05-01

The astrophysical s-process is a sequence of neutron-capture and beta-decay reactions on a slow time scale compared to beta-decay lifetimes near the line of stability. We systematically study this detailed sequence of neutron capture, continuum and bound-state beta decay, positron decay, and electron-capture reactions that comprise the s-process for a broad range of astrophysical environments. Our results are then compared with the solar-system abundances of heavy elements to determine the range of physical conditions responsible for their nucleosynthesis. The nuclear data needs are extensive but have begun to be precise enough to allow for a consistent interpretation of the astrophysical site for the s-process.

Norms Versus Security: What is More Important to Japan’s View of Nuclear Weapons

Science.gov (United States)

2017-03-01

SECURITY : WHAT IS MORE IMPORTANT TO JAPAN’S VIEW OF NUCLEAR WEAPONS? by Calvin W. Dillard March 2017 Thesis Advisor: S. Paul Kapur Second...TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE NORMS VERSUS SECURITY : WHAT IS MORE IMPORTANT TO JAPAN’S VIEW OF NUCLEAR WEAPONS... security concerns and technology are important in determining whether a nation will create a weapons program while politics, economics, and security

IAEA advisory group meeting on nuclear data for radiation damage assessment and related safety aspects, Vienna, 12-16 October 1981

International Nuclear Information System (INIS)

Kocherov, N.

1982-01-01

This Advisory Group Meeting on Nuclear Data for Radiation Damage Assessment and Related Safety Aspects was convened by the IAEA Nuclear Data Section, at IAEA Headquarters in Vienna, Austria, from 12-16 October 1981. The meeting was attended by 34 participants from 15 countries and 2 international organizations. The main objective of the meeting was to review the requirements for and the status of nuclear data needed for radiation damage estimates in reactor structural materials and related reactor safety aspects, and to develop recommendations to the Nuclear Data Section of the IAEA for its future activities in this field. (author)

SSI's Review of the RDandD Program 2004 of the Swedish Nuclear Fuel and Waste Management Co; SSI:s granskning av SKB:s Fud-program 2004

Energy Technology Data Exchange (ETDEWEB)

Larsson, Carl-Magnus; Hedberg, Bjoern; Wiebert, Anders [and others

2005-06-01

In this report the Swedish Radiation Protection Authority's (SSI) review of the Swedish Nuclear Fuel and Waste Management Company's (SKB) RDandD programme 2004 is presented. In the review SSI comments, among other things, SKB's plan of action and future direction of SKB's RDandD programme, need for different types of consultations, plans for demonstration of canister deposition and long term experiments, and strategies for dismantling of nuclear facilities.

The Nuclear Energy Option for the U.S. - How Far Are We from Public Acceptance?

International Nuclear Information System (INIS)

Biedscheid, J.A.; Devarakonda, M.

2004-01-01

The recent rise of oil and gasoline prices accompanied by reluctant acknowledgement that traditional sources of energy are limited has renewed public interest in renewable energy sources. This perspective on energy is focusing attention on and facilitating acceptance of alternative energy concepts, such as solar, wind, and biomass. The nuclear energy alternative, while clean with potentially abundant fuel supplies and associated with low costs, is burdened with the frequently negative public opinion reserved for things nuclear. Coincident with the heightened examination of alternative energy concepts, 2004 marks the 25-year anniversary of the Three Mile Island accident. Since this pivotal accident in 1979, no new reactor licenses have been granted in the U.S. The resolution of the issues of nuclear waste management and disposition are central to and may advance public discussions of the future use of nuclear energy. The U.S. Department of Energy (DOE) is currently preparing the licensing application for Yucca Mountain, which was designated in 2003 as the site for a high-level waste and spent nuclear fuel repository in the U.S. The DOE also has been operating a deep geologic repository for the permanent disposal of transuranic (TRU) waste since 1999. The operational status of the Waste Isolation Pilot Plant (WIPP) as a repository for TRU waste was successfully realized along with the lesson learned that stakeholder trust and acceptance are as critical to the success of a repository program as the resolution of technical issues and obtaining regulatory approvals. For the five years of its operation and for decades prior, the challenge of attaining public acceptance of the WIPP has persisted for reasons aligned with the opposition to nuclear energy. Due to this commonality, the nuclear waste approach to public acceptance, with its pros and cons, provides a baseline for the examination of an approach for the public acceptance of nuclear energy in the U.S. This paper

Virginia Power's nuclear operations: Leading by example

Energy Technology Data Exchange (ETDEWEB)

Kuehn, S.E.

1995-02-01

Success has been a long time coming for Virginia Power's nuclear units, but after a record run and some of the shortest refueling outages ever, the rest of the industry could learn a few things. This article describes the changes made by Virginia Power at its Surry and North Anna plants. Virginia Power's recipe for success called for equal amounts of individual initiative, management savvy, engineering discipline, organization, dedication, perseverance, pride, introspection, motivation, and humility.

The Department of Homeland Security’s Approach to Countering Nuclear Terrorism through Detection and Technical Forensics

Directory of Open Access Journals (Sweden)

Huban A. Gowadia

2015-07-01

Full Text Available To combat the threat of nuclear terrorism, the Domestic Nuclear Detection Office (DNDO was established within the U.S. Department of Homeland Security to focus efforts on developing and enhancing radiological and nuclear detection and national technical nuclear forensics capabilities. With respect to nuclear detection, we at DNDO, in concert with interagency partners, are developing and enhancing a multi-faceted, layered, defense-in-depth framework to make prohibitively difficult the importation, possession, storage, development, transportation, or use of nuclear or other radioactive material that is out of regulatory control. In furtherance of this framework, we conduct research and development on detection and forensics technologies, characterize system performance, acquire and deploy detection systems, and support operational partners with the development of programs to effectively perform detection operations. To support the U.S. Government’s (USG attribution process, we focus on improving the readiness of the overarching USG forensic capabilities; advancing the technical capabilities to perform forensic analyses on pre-detonation nuclear and other radioactive materials; and building and sustaining an expertise pipeline for nuclear forensic scientists. These efforts, coupled with the work of interagency partners, will advance USG capabilities to detect and interdict a nuclear threat and hold accountable those who are responsible for such actions.

U.S. Nuclear Regulatory Commission human factors program plan

International Nuclear Information System (INIS)

1986-04-01

The purpose of the U.S. Nuclear Regulatory Commission (NRC) Human Factors Program Plan is to ensure that proper consideration is given to human factors in the design and operation of nuclear facilities. This revised plan addresses human factors issues related to the operation of nuclear power plants (NPPs). The three issues of concern are (1) the activities planned to provide the technical bases to resolve the remaining tasks related to human factors as described in NUREG-0660, The NRC Action Plan Developed as a Result of the TMI-2 Accident, and NUREG-0737, Clarification of TMI Action Plan Requirements; (2) the need to address the additional human factors efforts that were identified during implementation of the Action Plan; and (3) the actual fulfillment of those developmental activities specified in Revision 1 of this plan. The plan represents a systematic approach for addressing high priority human factors concerns important to NPP safety in FY 1986 through 1987

The U.S. Nuclear Regulatory Commission seismic safety research program

International Nuclear Information System (INIS)

Kenneally, R.M.; Guzy, D.J.; Murphy, A.J.

1988-01-01

The seismic safety research program sponsored by the U.S. Nuclear Regulatory Commission is directed toward improving the evaluation of potential earthquake effects on nuclear power plant operations. The research has been divided into three major program areas: earth sciences, seismic design margins, and fragilities and response. A major thrust of this research is to assess plant behavior for seismic events more severe and less probable than those considered in design. However, there is also research aimed at improving the evaluation of earthquake input and plant response at plant design levels

Nuclear safety cooperation in Southeast Asia. Lessons from Asia's regional networks

International Nuclear Information System (INIS)

Trajano, Julius Cesar I.

2017-01-01

Debate has been ongoing among key stakeholders on whether South-east Asia should use or reject nuclear power. However, there are still significant regional concerns over nuclear safety and security in South-east Asia. As some ASEAN countries plan to pursue nuclear power, they need to create and maintain a pool of local nuclear professionals with actual relevant experience in the nuclear industry. While the IAEA does not influence a country's decision on introducing nuclear power, it supports Member States' efforts to evaluate all options towards making a knowledgeable decision. Nuclear safety is the responsibility of every nation that utilizes nuclear technology. National governments are responsible for regulations that govern how safety at nuclear facilities is maintained, as well as to reduce radiation risks, including emergency response and recovery actions. But nuclear energy has transboundary/ regional implications if nuclear safety in each member state is not strengthened. ASEAN countries share a common goal in achieving high level of public safety and confidence in nuclear and radiation related issues. Can regional cooperation help ASEAN Member-States strengthen nuclear safety? The paper examines the importance of regional cooperation on nuclear energy governance and the role of regional organisations in Asia in strengthening nuclear safety cooperation and emergency preparedness and response in Southeast Asia. (author)

Detection of new variant “Off-ladder” at the D12S391, D19S433 and ...

African Journals Online (AJOL)

Detection of new variant “Off-ladder” at the D12S391, D19S433 and D1S1656 ... African Journal of Biotechnology ... PCR products were detected by genetic analyzer 3130xL then, the data processed and analyzed by PowerStatsV1.2 software.

SKI's engagement in the process for siting a spent nuclear fuel repository

Energy Technology Data Exchange (ETDEWEB)

Paeivioe Jonsson, Josefin; Westerlind, Magnus [Swedish Nuclear Power Inspectorate, Stockholm (Sweden)

2006-09-15

In Sweden, issues concerning the disposal of nuclear waste historically required co-operation among primarily two main actors: The nuclear industry and the state. Municipalities involved in SKB's feasibility studies objected to the fact that they lacked resources to keep the people in the municipality informed about the ongoing work. As a result the Parliament decided that municipalities involved in SKB's siting process should receive money from the nuclear waste fund for their engagement. Since 2005 resources also have been made available for NGO's participating in SKB's ongoing EIA-process. In total they can yearly receive up to 2.5 million Swedish kronor. The fact that new actors continuously have been engaged in disposal of spent nuclear fuel has meant that 'old' actors, particularly SKB, the regulators (the Swedish Nuclear Power Inspectorate, SKI, and the Swedish Radiation Protection Authority, SSI) have had to evaluate, develop and clarify their roles and strategies for dialogue and regulatory oversight. This paper presents the effects the increased engagement has had on SKI's regulatory activities. Looking back it is possible to identify two well-defined break points in SKI's views on communication and active participation in the siting process. The first was the so-called DIALOGUE-project, which was initiated by SKI in the early 1990s. In this research project there were participants from e.g. SKI and SSI, municipalities and environmental organisations. The two most important conclusions for SKI were firstly that regulators can and should participate already in the early stages of a siting process, and that this can be done without loosing credibility as an independent reviewer of a licence application and secondly that actors (in the siting process) with conflicting interests and views can reach agreement on the basis for decisions. The second break point occurred in the mid 1990s when SKB announced that the

Redefining the U.S. Agenda for Nuclear Disarmament, Analysis and Reflections

Energy Technology Data Exchange (ETDEWEB)

Dunn, Lewis A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). Center for Global Security Research

2016-10-01

With Lewis Dunn’s paper on nuclear disarmament diplomacy, we are inaugurating a new monograph series under the auspices of the Center for Global Security Research at Lawrence Livermore National Laboratory. The series will explore complex emerging challenges in the emerging security environment as they bear on issues of deterrence, assurance, and strategic stability. Our goal is to explore these issues deeply enough to provide significant new understanding that is technically informed and policy relevant. Our premise is that thoughtful students of international security affairs continue to value such in-depth analysis as a way to help make sense of the large flow of data and opinion that reaches all of us on a daily basis. Our ambition is to generate four to six such papers per year on especially salient topics. The views expressed in these papers are those of the author and should not be attributed to the Center, the Laboratory, or the U.S. government. This inaugural paper addresses one of the key questions facing national leadership seven to eight years after President Obama’s April 2009 remarks in Prague and his commitment to take practical steps towards the long-term goal of the elimination of nuclear weapons. In the interim, some important steps have been taken. But there have also been many disappointments. The new presidential administration will face a security landscape quite different from that of eight years ago and must reassess U.S. priorities and approaches. As Lewis Dunn argues, some will be tempted to walk away entirely from the disarmament agenda, while others will advocate even more forcefully for unilateral U.S. steps to further reduce the role and number of nuclear weapons in its posture. Dr. Dunn sets out his own vision of how to adapt and carry forward the disarmament agenda, in a manner informed by developments in the security environment that point to a continuing role for nuclear deterrence. The result is both fresh and compelling.

Secretion of S100A8, S100A9, and S100A12 by Neutrophils Involves Reactive Oxygen Species and Potassium Efflux

Directory of Open Access Journals (Sweden)

Mélanie R. Tardif

2015-01-01

Full Text Available S100A8/A9 (calprotectin and S100A12 proinflammatory mediators are found at inflammatory sites and in the serum of patients with inflammatory or autoimmune diseases. These cytoplasmic proteins are secreted by neutrophils at sites of inflammation via alternative secretion pathways of which little is known. This study examined the nature of the stimuli leading to S100A8/A9 and S100A12 secretion as well as the mechanism involved in this alternative secretion pathway. Chemotactic agents, cytokines, and particulate molecules were used to stimulate human neutrophils. MSU crystals, PMA, and H2O2 induced the release of S100A8, S100A9, and S100A12 homodimers, as well as S100A8/A9 heterodimer. High concentrations of S100A8/A9 and S100A12 were secreted in response to nanoparticles like MSU, silica, TiO2, fullerene, and single-wall carbon nanotubes as well as in response to microbe-derived molecules, such as zymosan or HKCA. However, neutrophils exposed to the chemotactic factors fMLP failed to secrete S100A8/A9 or S100A12. Secretion of S100A8/A9 was dependent on the production of reactive oxygen species and required K+ exchanges through the ATP-sensitive K+ channel. Altogether, these findings suggest that S100A12 and S100A8/A9 are secreted independently either via distinct mechanisms of secretion or following the activation of different signal transduction pathways.

The Y-12 National Security Complex Foreign Research Reactor Uranium Supply Production

Energy Technology Data Exchange (ETDEWEB)

Nelson, T. [Nuclear Technology and Nonproliferation Programs, B and W Y-12, L.L.C., Y-12 National Security Complex, Oak Ridge, Tennessee (United States); Keller, A.P. [Disposition and Supply Programs, B and W Y-12, L.L.C., Y-12 National Security Complex, Oak Ridge, Tennessee (United States)

2011-07-01

The Foreign Research Reactor (FRR) Uranium Supply Program at the Y-12 National Security Complex supports the nonproliferation objectives of the National Nuclear Security Administration (NNSA) HEU Disposition, the Reduced Enrichment Research and Test Reactors (RERTR), and the United States (U.S.) FRR Spent Nuclear Fuel (SNF) Acceptance Programs. The FRR Supply Program supports the important U.S. government nuclear nonproliferation commitment to serve as a reliable and cost-effective uranium supplier for those foreign research reactors that are converting or have converted to Low-Enriched Uranium (LEU) fuel under the RERTR Program. The NNSA Y-12 Site Office maintains the prime contracts with foreign government agencies for the supply of LEU for their research reactors. The LEU is produced by down blending Highly Enriched Uranium (HEU) that has been declared surplus to the U.S. national defense needs. The down blending and sale of the LEU supports the Surplus HEU Disposition Program Record of Decision to make the HEU non-weapons usable and to recover the economic value of the uranium to the extent feasible. In addition to uranium metal feedstock for fuel fabrication, Y-12 can produce LEU in different forms to support new fuel development or target fabrication for medical isotope production. With production improvements and efficient delivery preparations, Y-12 continues to successfully support the global research reactor community. (author)

Microscopic evidence for magnetic ordering in NdCu3Ru4O12 : 63,65Cu nuclear quadrupole resonance study

Science.gov (United States)

Yogi, M.; Niki, H.; Hedo, M.; Komesu, S.; Nakama, T.

2018-05-01

We have conducted 63,65Cu nuclear quadrupole resonance (NQR) measurements on A-site ordered perovskite compounds LaCu3Ru4O12 and NdCu3Ru4O12 to investigate their ground state and spin fluctuations. While there is only one Cu site in the crystal structure, multiple NQR resonance lines were observed. This is presumed to be due to the presence of slight distortion and lattice defects in the samples. The nuclear spin-lattice relaxation rate divided by temperature, 1 /T1 T , for LaCu3Ru4O12 showed almost constant value indicating the Fermi-liquid state. A remarkable increase in 1 /T1 T due to spin fluctuations was observed in NdCu3Ru4O12 . Furthermore, an evident magnetic phase transition at TM = 0.6 K was revealed from the distinct peak of 1 /T1 T and the broadening of the NQR spectrum.

Japan's search for identity in the nuclear age

Energy Technology Data Exchange (ETDEWEB)

Kenzaburo, O.

Japan's position has been one of an outsider in the nuclear age at the same time it has been a victim to the first use of atomic weapons. Quoting from Japanese poets and writers, the author constructs a model of the time to create an image of modern Japan's cultural identity as a result of the Meiji Restoration and the close of World War II. The end of the Emperor System and alienation from the rest of Asia are significant consequences of these events. The author feels that current arguments that Japan should arm itself with nuclear weapons ignore the miseries Japan alone has felt and should be restricted. Although a new Japanism which is oriented away from western culture is emerging today, efforts to rediscover the folk culture can also recapture the nonnuclear vision of 1945. (DCK)

Overview of the U. S. flight safety process for space nuclear power

International Nuclear Information System (INIS)

Bennett, G.L.

1981-01-01

The two current types of nuclear power sources used in U. S. spacecraft are described along with the flight safety philosophies governing their use. In the case of radioisotope thermoelectric generators, the design philosophy consists of containment, immobilization, and recovery of the nuclear materials. For reactors, the emphasis is on maintaining a subcritical configuration in all credible accident environments. To document the safety activities, a safety analysis report is prepared for each mission. These reports, which are based on the probabilistic risk assessment methodology pioneered by the space nuclear safety community, are subjected to an interagency safety review before a recommendation is made to approve the launch of a nuclear-powered spacecraft

Du vinyle à YouTube : les habitudes de consommation et de recherche de musique des jeunes adultes québécois

Directory of Open Access Journals (Sweden)

Ariane Legault-Venne

2017-02-01

Full Text Available Il existe peu d’études récentes sur les habitudes de consommation et le comportement dans la recherche d’information musicale au Québec et au Canada. Pourtant, les études réalisées sur le sujet dans d’autres pays suggèrent que l’évolution rapide des technologies a entraîné des changements importants dans les habitudes et comportements des amateurs de musique. Il est essentiel d’avoir une bonne connaissance de ces pratiques pour concevoir des systèmes de repérage et d’exploration de la musique qui répondent aux besoins réels de leurs utilisateurs. Cet article présente les résultats d’une enquête menée auprès de 278 personnes âgées de 18 à 35 ans habitant au Québec. Les objectifs de l’enquête étaient de mieux connaître les habitudes d’achat et d’écoute de musique des jeunes adultes québécois ainsi que la façon dont ils s’y prennent pour découvrir de nouveaux artistes et de nouvelles musiques. Les résultats révèlent que les services d’écoute de musique en continu et les sites de partage de vidéos étaient utilisés par 78% des répondants. Malgré la popularité croissante de ces services, les jeunes québécois n’ont pas totalement délaissé certaines pratiques plus traditionnelles. Ils continuent de valoriser les recommandations musicales de leurs proches, d’écouter de la musique sur CD et d’acheter des fichiers musicaux, même si ces pratiques sont de moins en moins fréquentes. Very few recent studies have focused on Quebeckers’ and Canadians’ consumption and information-seeking behaviour of music for leisure. However, studies conducted in other countries suggest that the rapid evolution of technologies has resulted in important changes in practices. It is essential to gain a better knowledge of these new practices to design music information retrieval and exploration systems that meet the real needs of users. This article presents the results of a survey of 278 younger

ADAM12-S stimulates bone growth in transgenic mice by modulating chondrocyte proliferation and maturation

DEFF Research Database (Denmark)

Kveiborg, Marie; Albrechtsen, Reidar; Rudkjaer, Lise

2006-01-01

ADAM12-S transgenic mice exhibit a pronounced increase in the length of bones, such as femur, tibia, and vertebrae. The effect of ADAM12-S on longitudinal bone growth involves the modulation of chondrocyte proliferation and maturation, likely through proteolytic activities and altered cell......: Transgenic mice expressing the secreted form of human ADAM12, ADAM12-S, or a truncated metalloprotease-deficient form of ADAM12-S in the circulation were used to study the effects of ADAM12 on the skeleton. In addition, murine chondrocyte cultures were used to study the effect of ADAM12-S on cell...... studies showed that ADAM12-S inhibits chondrocyte adhesion to fibronectin and collagen type II. CONCLUSIONS: ADAM12-S stimulates bone growth in mice by modulating chondrocyte proliferation and maturation through mechanisms probably involving both metalloprotease and adhesion activities....

WINCO's experience with environmental compliance at 1950's vintage DOE nuclear facilities

International Nuclear Information System (INIS)

Porter, C.L.

1992-01-01

During the 1950's numerous nuclear facilities were built under the auspices of the Atomic Energy Commission (AEC). One such facility, a nuclear fuels reprocessing facility located in Idaho has operated over the past 40 years. In the late 1980's federal facilities became subject to the same environmental regulations as commercial facilities. Since the Department of Energy's mission called for continued reprocessing at the Idaho facility, compliance with current environmental standards became necessary. Certified compliance was achieved with a minimum of modifications by capitalizing upon existing building features that resulted from original AEC design criteria

Risk Management and Nuclear Insurance Program within Societatea Nationala Nuclearelectrica S.A

International Nuclear Information System (INIS)

Havris, Alexandru

2008-01-01

This paper shall present the Risk Management and associated nuclear insurance program developed within Societatea Nationala 'Nuclearelectrica' S.A, owner and operator of Units 1 and 2 Cernavoda NPP, the Nuclear Fuel Plant and in charge with commissioning of Units 3 and 4. From the risk management perspective, the main aspects that energy industry has to face due to global economic changes within a dynamic business environment are highlighted. In order to mitigate the operational and investment associated risks, Societatea Nationala 'Nuclearelectrica' S.A. successfully developed, implemented and maintained a coherent insurance program both on local and international insurance market. (authors)

Application of AdS/CFT in Nuclear Physics

Directory of Open Access Journals (Sweden)

M. R. Pahlavani

2014-01-01

Full Text Available We review some recent progress in studying the nuclear physics especially nucleon-nucleon (NN force within the gauge-gravity duality, in context of noncritical string theory. Our main focus is on the holographic QCD model based on the AdS6 background. We explain the noncritical holography model and obtain the vector-meson spectrum and pion decay constant. Also, we study the NN interaction in this frame and calculate the nucleonmeson coupling constants. A further topic covered is a toy model for calculating the light nuclei potential. In particular, we calculate the light nuclei binding energies and also excited energies of some available excited states. We compare our results with the results of other nuclear models and also with the experimental data. Moreover, we describe some other issues which are studied using the gauge-gravity duality.

Authors of clinical trials reported individual and financial conflicts of interest more frequently than institutional and nonfinancial ones: a methodological survey.

Science.gov (United States)

Hakoum, Maram B; Jouni, Nahla; Abou-Jaoude, Eliane A; Hasbani, Divina Justina; Abou-Jaoude, Elias A; Lopes, Luciane Cruz; Khaldieh, Mariam; Hammoud, Mira Z; Al-Gibbawi, Mounir; Anouti, Sirine; Guyatt, Gordon; Akl, Elie A

2017-07-01

Conflicts of interest (COIs) are increasingly recognized as important to disclose and manage in health research. The objective of this study was to assess the reporting of both financial and nonfinancial COI by authors of randomized controlled trials published in a representative sample of clinical journals. We searched Ovid Medline and included a random sample of 200 randomized controlled trials published in 2015 in one of the 119 Core Clinical Journals. We classified COI using a comprehensive framework that includes the following: individual COIs (financial, professional, scholarly, advocatory, personal) and institutional COIs (financial, professional, scholarly, and advocatory). We conducted descriptive and regression analyses. Of the 200 randomized controlled trials, 188 (94%) reported authors' COI disclosures that were available in the main document (92%) and as International Committee of Medical Journal Editors forms accessible online (12%). Of the 188 trials, 57% had at least one author reporting at least one COI; in all these trials, at least one author reported financial COI. Institutional COIs (11%) and nonfinancial COIs (4%) were less commonly reported. References to COI disclosure statements for editors (1%) and medical writers (0%) were seldom present. Regression analyses showed positive associations between reporting individual financial COI and higher journal impact factor (odds ratio [OR] = 1.06, 95% confidence interval [CI] = 1.02-1.10), larger number of authors (OR = 1.10, 95% CI 1.02-1.20), affiliation with an institution from a high-income country (OR = 16.75, 95% CI 3.38-82.87), and trials reporting on pharmacological interventions (OR = 2.28, 95% CI 1.13-4.62). More than half of published randomized controlled trials report that at least one author has a COI. Trial authors report financial COIs more often than nonfinancial COIs and individual COIs more frequently than institutional COIs. Copyright © 2017 Elsevier Inc. All rights

Summer Schools in Nuclear and Radiochemistry

Energy Technology Data Exchange (ETDEWEB)

Silber, Herbert B. [San Jose State University

2013-06-20

The ACS Summer Schools in Nuclear and Radiochemistry (herein called “Summer Schools”) were funded by the U.S. Department of Energy and held at San Jose State University (SJSU) and Brookhaven National Laboratory (BNL). The Summer Schools offer undergraduate students with U.S. citizenship an opportunity to complete coursework through ACS accredited chemistry degree programs at SJSU or the State University of New York at Stony Brook (SBU). The courses include lecture and laboratory work on the fundamentals and applications of nuclear and radiochemistry. The number of students participating at each site is limited to 12, and the low student-to-instructor ratio is needed due to the intense nature of the six-week program. To broaden the students’ perspectives on nuclear science, prominent research scientists active in nuclear and/or radiochemical research participate in a Guest Lecture Series. Symposia emphasizing environmental chemistry, nuclear medicine, and career opportunities are conducted as a part of the program. The Department of Energy’s Office of Basic Energy Sciences (BES) renewed the five-year proposal for the Summer Schools starting March 1, 2007, with contributions from Biological and Environmental Remediation (BER) and Nuclear Physics (NP). This Final Technical Report covers the Summer Schools held in the years 2007-2011.

Application and development of peer review in China's nuclear power industry

International Nuclear Information System (INIS)

Huang Ping

2014-01-01

Peer review is one of the scientific methods and tools in management, which plays an active role in promoting and improving the performance of safe operation and management level of nuclear power plants. Peer review of nuclear power is not only comprehensively popularized and applied in China, but it is also innovated and developed in industry at all levels in recent years. In this paper, with the CNNC's relevant practice as main line, a variety of accepted peer review methods both at home and abroad were compared and analyzed, and the current application and development of peer review in China's nuclear power industry were described, as well as some suggestions for improvement were put forward to share with our craft brothers. (author)

NECSA'S Need to Establish a Nuclear Forensics Specific NDA Facility for On-Site Categorization of Seized Nuclear Materials

International Nuclear Information System (INIS)

Boshielo, P.; Mogafe, R.

2015-01-01

The increase of nuclear material that are out of regulatory control is becoming a serious concern and threat and thereby continuously seeking urgent interventions and counteractions from the international community aspiring effective control over all nuclear material and peaceful uses of nuclear technologies globally. In South Africa the nuclear forensics initiative approach and its execution have been adopted, established and managed by the South African Nuclear Energy Corporation (NECSA) to support the country's nuclear safeguards system and nuclear security investigations plan to fight against the illicit trafficking of nuclear and radioactive materials. On this nuclear forensics initiative approach adopted by Necsa, the development and later execution of a Non-Destructive Analyses (NDA) facility capability for quick categorization of any seized nuclear material by law-enforcement agencies is currently envisaged as a critical initiative to comprehend nuclear forensics Laboratory analytical or characterization techniques. The main objective for this NDA facility is planned to be used for performing nuclear material screening process for material categorization purposes to generate information and results which will be open to law enforcement agencies for prosecution processes and also for the safeguards reporting to the IAEA (ITDB). The NDA technique is therefore found to be a critical tool needed at NECSA as an Early-Checking-Point or first-line material check point for all seized nuclear materials in determining some characteristics of the materials and collection of data without having to destroy or changing the morphology of the material. (author)

Olopatadine Suppresses the Migration of THP-1 Monocytes Induced by S100A12 Protein

Directory of Open Access Journals (Sweden)

2006-01-01

Full Text Available Olopatadine hydrochloride (olopatadine is an antiallergic drug with histamine H 1 receptor antagonistic activity. Recently, olopatadine has been shown to bind to S100A12 which is a member of the S100 family of calcium-binding proteins, and exerts multiple proinflammatory activities including chemotaxis for monocytes and neutrophils. In this study, we examined the possibility that the interaction of olopatadine with S100A12 inhibits the proinflammatory effects of S100A12. Pretreatment of olopatadine with S100A12 reduced migration of THP-1, a monocyte cell line, induced by S100A12 alone, but did not affect recombinant human regulated upon activation, normal T cell expressed and secreted (RANTES-induced migration. Amlexanox, which also binds to S100A12, inhibited the THP-1 migration induced by S100A12. However, ketotifen, another histamine H 1 receptor antagonist, had little effect on the activity of S100A12. These results suggest that olopatadine has a new mechanism of action, that is, suppression of the function of S100A12, in addition to histamine H 1 receptor antagonistic activity.

International Nuclear Security Education Network (INSEN): Promoting nuclear security education

International Nuclear Information System (INIS)

Muhamad Samudi Yasir

2013-01-01

Full-text: The need for human resource development programmes in nuclear security was underlined at several International Atomic Energy Agency (IAEA) General Conferences and Board of Governors Meetings. Successive IAEA Nuclear Security Plans, the most recent of which was agreed by the Board of Governors in September 2009, give high priority to assisting States in establishing educational programmes in nuclear security in order to ensure the sustainability of nuclear security improvements. The current Nuclear Security Plan 1 covering 2010-2013 emphasizes on the importance of considering existing capacities at international, regional and national levels while designing nuclear security academic programmes. In the course of implementing the Plan, the IAEA developed a guide entitled Educational Programme in Nuclear Security (IAEA Nuclear Security Series No. 12) that consists of a model of a MAster of Science (M.Sc.) and a Certificate Programme in Nuclear Security. This guide was aims at assisting universities or other educational institutes to developed academic programmes in nuclear security. Independently, some universities already offered academic programmes covering some areas of nuclear security, while other universities have asked the IAEA to support the implementation of these programmes. In order to better address current and future request for assistance in this area, the IAEA establish a collaboration network-International Nuclear Security Education Network (INSEN), among universities who are providing nuclear security education or who are interested in starting an academic programme/ course(s) in nuclear security. Universiti Kebangsaan Malaysia (UKM) is a first local university became a member of INSEN since the beginning of the establishment. (author)

eta-nuclear bound states revisited

Czech Academy of Sciences Publication Activity Database