Architecture for Cognitive Networking within NASA's Future Space Communications Infrastructure

Science.gov (United States)

Clark, Gilbert; Eddy, Wesley M.; Johnson, Sandra K.; Barnes, James; Brooks, David

2016-01-01

Future space mission concepts and designs pose many networking challenges for command, telemetry, and science data applications with diverse end-to-end data delivery needs. For future end-to-end architecture designs, a key challenge is meeting expected application quality of service requirements for multiple simultaneous mission data flows with options to use diverse onboard local data buses, commercial ground networks, and multiple satellite relay constellations in LEO, GEO, MEO, or even deep space relay links. Effectively utilizing a complex network topology requires orchestration and direction that spans the many discrete, individually addressable computer systems, which cause them to act in concert to achieve the overall network goals. The system must be intelligent enough to not only function under nominal conditions, but also adapt to unexpected situations, and reorganize or adapt to perform roles not originally intended for the system or explicitly programmed. This paper describes an architecture enabling the development and deployment of cognitive networking capabilities into the envisioned future NASA space communications infrastructure. We begin by discussing the need for increased automation, including inter-system discovery and collaboration. This discussion frames the requirements for an architecture supporting cognitive networking for future missions and relays, including both existing endpoint-based networking models and emerging information-centric models. From this basis, we discuss progress on a proof-of-concept implementation of this architecture, and results of implementation and initial testing of a cognitive networking on-orbit application on the SCaN Testbed attached to the International Space Station.

24 CFR 570.614 - Architectural Barriers Act and the Americans with Disabilities Act.

Science.gov (United States)

2010-04-01

... with disabilities. Further, the ADA requires the removal of architectural barriers and communication... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Architectural Barriers Act and the... GRANTS Other Program Requirements § 570.614 Architectural Barriers Act and the Americans with...

Between architecture and model: Strategies for cognitive control

NARCIS (Netherlands)

Taatgen, Niels

One major limitation of current cognitive architectures is that models are typically constructed in an “empty” architecture, and that the knowledge specifications (typically production rules) are specific to the particular task. This means that general cognitive control strategies have to be

Strategies for memory-based decision making: Modeling behavioral and neural signatures within a cognitive architecture.

Science.gov (United States)

Fechner, Hanna B; Pachur, Thorsten; Schooler, Lael J; Mehlhorn, Katja; Battal, Ceren; Volz, Kirsten G; Borst, Jelmer P

2016-12-01

How do people use memories to make inferences about real-world objects? We tested three strategies based on predicted patterns of response times and blood-oxygen-level-dependent (BOLD) responses: one strategy that relies solely on recognition memory, a second that retrieves additional knowledge, and a third, lexicographic (i.e., sequential) strategy, that considers knowledge conditionally on the evidence obtained from recognition memory. We implemented the strategies as computational models within the Adaptive Control of Thought-Rational (ACT-R) cognitive architecture, which allowed us to derive behavioral and neural predictions that we then compared to the results of a functional magnetic resonance imaging (fMRI) study in which participants inferred which of two cities is larger. Overall, versions of the lexicographic strategy, according to which knowledge about many but not all alternatives is searched, provided the best account of the joint patterns of response times and BOLD responses. These results provide insights into the interplay between recognition and additional knowledge in memory, hinting at an adaptive use of these two sources of information in decision making. The results highlight the usefulness of implementing models of decision making within a cognitive architecture to derive predictions on the behavioral and neural level. Copyright © 2016 Elsevier B.V. All rights reserved.

77 FR 36231 - Americans With Disabilities Act (ADA) and Architectural Barriers Act (ABA) Accessibility...

Science.gov (United States)

2012-06-18

...-0004] RIN 3014-AA39 Americans With Disabilities Act (ADA) and Architectural Barriers Act (ABA... (ADA) and Architectural Barriers Act (ABA) Accessibility Guidelines to specifically address emergency... ensure that newly constructed and altered emergency transportable housing units covered by the ADA or ABA...

Extending the Soar Cognitive Architecture

National Research Council Canada - National Science Library

Laird, John E

2007-01-01

.... Specifically looking at extensions related to memory and learning (episodic, semantic) and emotion. The direction changed when an opportunity became available to collaborate with other biologically-inspired cognitive architecture...

A Layered Active Memory Architecture for Cognitive Vision Systems

OpenAIRE

Kolonias, Ilias; Christmas, William; Kittler, Josef

2007-01-01

Recognising actions and objects from video material has attracted growing research attention and given rise to important applications. However, injecting cognitive capabilities into computer vision systems requires an architecture more elaborate than the traditional signal processing paradigm for information processing. Inspired by biological cognitive systems, we present a memory architecture enabling cognitive processes (such as selecting the processes required for scene understanding, laye...

Tracking cognitive processing stages with MEG : A spatio-temporal model of associative recognition in the brain

NARCIS (Netherlands)

Borst, Jelmer P; Ghuman, Avniel S; Anderson, John R

2016-01-01

In this study, we investigated the cognitive processing stages underlying associative recognition using MEG. Over the last four decades, a model of associative recognition has been developed in the ACT-R cognitive architecture. This model was first exclusively based on behavior, but was later

Cognitive Architecture of Common and Scientific Concepts

Science.gov (United States)

Tarábek, Paul

2010-07-01

The cognitive architecture of concept is a specific structure consisting of the concept core, concept periphery, the semantic frame as the meaning and the sense of the concept, and the relations among all components of this structure. The model of the cognitive architecture of scientific and common concepts is a conceptual meta-model built upon Vygotsky's concept theory, Fillmore's semantic frame, semantic triangle, on widespread ideas of the structuring of conceptual systems, and the Hestenes' Modeling Theory. The method of semantic mapping of concepts flowing from the model is designed.

Visualization of decision processes using a cognitive architecture

Science.gov (United States)

Livingston, Mark A.; Murugesan, Arthi; Brock, Derek; Frost, Wende K.; Perzanowski, Dennis

2013-01-01

Cognitive architectures are computational theories of reasoning the human mind engages in as it processes facts and experiences. A cognitive architecture uses declarative and procedural knowledge to represent mental constructs that are involved in decision making. Employing a model of behavioral and perceptual constraints derived from a set of one or more scenarios, the architecture reasons about the most likely consequence(s) of a sequence of events. Reasoning of any complexity and depth involving computational processes, however, is often opaque and challenging to comprehend. Arguably, for decision makers who may need to evaluate or question the results of autonomous reasoning, it would be useful to be able to inspect the steps involved in an interactive, graphical format. When a chain of evidence and constraint-based decision points can be visualized, it becomes easier to explore both how and why a scenario of interest will likely unfold in a particular way. In initial work on a scheme for visualizing cognitively-based decision processes, we focus on generating graphical representations of models run in the Polyscheme cognitive architecture. Our visualization algorithm operates on a modified version of Polyscheme's output, which is accomplished by augmenting models with a simple set of tags. We provide example visualizations and discuss properties of our technique that pose challenges for our representation goals. We conclude with a summary of feedback solicited from domain experts and practitioners in the field of cognitive modeling.

Cognitive Architectures and Autonomy: A Comparative Review

Science.gov (United States)

Thórisson, Kristinn; Helgasson, Helgi

2012-05-01

One of the original goals of artificial intelligence (AI) research was to create machines with very general cognitive capabilities and a relatively high level of autonomy. It has taken the field longer than many had expected to achieve even a fraction of this goal; the community has focused on building specific, targeted cognitive processes in isolation, and as of yet no system exists that integrates a broad range of capabilities or presents a general solution to autonomous acquisition of a large set of skills. Among the reasons for this are the highly limited machine learning and adaptation techniques available, and the inherent complexity of integrating numerous cognitive and learning capabilities in a coherent architecture. In this paper we review selected systems and architectures built expressly to address integrated skills. We highlight principles and features of these systems that seem promising for creating generally intelligent systems with some level of autonomy, and discuss them in the context of the development of future cognitive architectures. Autonomy is a key property for any system to be considered generally intelligent, in our view; we use this concept as an organizing principle for comparing the reviewed systems. Features that remain largely unaddressed in present research, but seem nevertheless necessary for such efforts to succeed, are also discussed.

Cognitive architectures: choreographing the dance of mental operations with the task environment.

Science.gov (United States)

Gray, Wayne D

2008-06-01

In this article, I present the ideas and trends that have given rise to the use of cognitive architectures in human factors and provide a cognitive engineering-oriented taxonomy of these architectures and a snapshot of their use for cognitive engineering. Architectures of cognition have had a long history in human factors but a brief past. The long history entails a 50-year preamble, whereas the explosion of work in the current decade reflects the brief past. Understanding this history is key to understanding the current and future prospects for applying cognitive science theory to human factors practice. The review defines three formative eras in cognitive engineering research: the 1950s, 1980s, and now. In the first era, the fledging fields of cognitive science and human factors emphasized characteristics of the dancer the limited capacity or bounded rationality view of the mind, and the ballroom, the task environment. The second era emphasized the dance (i.e., the dynamic interaction between mental operations and task environment). The third era has seen the rise of cognitive architectures as tools for choreographing the dance of mental operations within the complex environments posed by human factors practice. Hybrid architectures present the best vector for introducing cognitive science theories into a renewed engineering-based human factors. The taxonomy provided in this article may provide guidance on when and whether to apply a cognitive science or a hybrid architecture to a human factors issue.

Developing Dynamic Field Theory Architectures for Embodied Cognitive Systems with cedar.

Science.gov (United States)

Lomp, Oliver; Richter, Mathis; Zibner, Stephan K U; Schöner, Gregor

2016-01-01

Embodied artificial cognitive systems, such as autonomous robots or intelligent observers, connect cognitive processes to sensory and effector systems in real time. Prime candidates for such embodied intelligence are neurally inspired architectures. While components such as forward neural networks are well established, designing pervasively autonomous neural architectures remains a challenge. This includes the problem of tuning the parameters of such architectures so that they deliver specified functionality under variable environmental conditions and retain these functions as the architectures are expanded. The scaling and autonomy problems are solved, in part, by dynamic field theory (DFT), a theoretical framework for the neural grounding of sensorimotor and cognitive processes. In this paper, we address how to efficiently build DFT architectures that control embodied agents and how to tune their parameters so that the desired cognitive functions emerge while such agents are situated in real environments. In DFT architectures, dynamic neural fields or nodes are assigned dynamic regimes, that is, attractor states and their instabilities, from which cognitive function emerges. Tuning thus amounts to determining values of the dynamic parameters for which the components of a DFT architecture are in the specified dynamic regime under the appropriate environmental conditions. The process of tuning is facilitated by the software framework cedar , which provides a graphical interface to build and execute DFT architectures. It enables to change dynamic parameters online and visualize the activation states of any component while the agent is receiving sensory inputs in real time. Using a simple example, we take the reader through the workflow of conceiving of DFT architectures, implementing them on embodied agents, tuning their parameters, and assessing performance while the system is coupled to real sensory inputs.

A cognitive robotics system: the symbolic and sub-symbolic robotic intelligence control system (SS-RICS)

Science.gov (United States)

Kelley, Troy D.; Avery, Eric

2010-04-01

This paper will detail the progress on the development of the Symbolic and Subsymbolic Robotics Intelligence Control System (SS-RICS). The system is a goal oriented production system, based loosely on the cognitive architecture, the Adaptive Control of Thought-Rational (ACT-R) some additions and changes. We have found that in order to simulate complex cognition on a robot, many aspects of cognition (long term memory (LTM), perception) needed to be in place before any generalized intelligent behavior can be produced. In working with ACT-R, we found that it was a good instantiation of working memory, but that we needed to add other aspects of cognition including LTM and perception to have a complete cognitive system. Our progress to date will be noted and the challenges that remain will be addressed.

41 CFR 102-76.60 - To which facilities does the Architectural Barriers Act apply?

Science.gov (United States)

2010-07-01

... PROPERTY 76-DESIGN AND CONSTRUCTION Architectural Barriers Act § 102-76.60 To which facilities does the Architectural Barriers Act apply? (a) The Architectural Barriers Act applies to any facility that is intended... the Architectural Barriers Act apply? 102-76.60 Section 102-76.60 Public Contracts and Property...

Developing dynamic field theory architectures for embodied cognitive systems with cedar

Directory of Open Access Journals (Sweden)

Oliver Lomp

2016-11-01

Full Text Available Embodied artificial cognitive systems such as autonomous robots or intelligent observers connect cognitive processes to sensory and effector systems in real time. Prime candidates for such embodied intelligence are neurally inspired architectures. While components such as forward neural networks are well established, designing pervasively autonomous neural architectures remains a challenge. This includes the problem of tuning the parameters of such architectures so that they deliver specified functionality under variable environmental conditions and retain these functions as the architectures are expanded. The scaling and autonomy problems are solved, in part, by dynamic field theory (DFT, a theoretical framework for the neural grounding of sensorimotor and cognitive processes. In this paper, we address how to efficiently build DFT architectures that control embodied agents and how to tune their parameters so that the desired cognitive functions emerge while such agents are situated in real environments. In DFT architectures, dynamic neural fields or nodes are assigned dynamic regimes, that is, attractor states and their instabilities, from which cognitive function emerges. Tuning thus amounts to determining values of the dynamic parameters for which the components of a DFT architecture are in the specified dynamic regime under the appropriate environmental conditions. The process of tuning is facilitated by the software framework cedar, which provides a graphical interface to build and execute DFT architectures. It enables to change dynamic parameters online and visualize the activation states of any component while the agent is receiving sensory inputs in real-time. Using a simple example, we take the reader through the workflow of conceiving of DFT architectures, implementing them on embodied agents, tuning their parameters, and assessing performance while the system is coupled to real sensory inputs.

CogWnet: A Resource Management Architecture for Cognitive Wireless Networks

KAUST Repository

Alqerm, Ismail

2013-07-01

With the increasing adoption of wireless communication technologies, there is a need to improve management of existing radio resources. Cognitive radio is a promising technology to improve the utilization of wireless spectrum. Its operating principle is based on building an integrated hardware and software architecture that configures the radio to meet application requirements within the constraints of spectrum policy regulations. However, such an architecture must be able to cope with radio environment heterogeneity. In this paper, we propose a cognitive resource management architecture, called CogWnet, that allocates channels, re-configures radio transmission parameters to meet QoS requirements, ensures reliability, and mitigates interference. The architecture consists of three main layers: Communication Layer, which includes generic interfaces to facilitate the communication between the cognitive architecture and TCP/IP stack layers; Decision-Making Layer, which classifies the stack layers input parameters and runs decision-making optimization algorithms to output optimal transmission parameters; and Policy Layer to enforce policy regulations on the selected part of the spectrum. The efficiency of CogWnet is demonstrated through a testbed implementation and evaluation.

Architecture of cognitive flexibility revealed by lesion mapping

Science.gov (United States)

Barbey, Aron K.; Colom, Roberto; Grafman, Jordan

2013-01-01

Neuroscience has made remarkable progress in understanding the architecture of human intelligence, identifying a distributed network of brain structures that support goal-directed, intelligent behavior. However, the neural foundations of cognitive flexibility and adaptive aspects of intellectual function remain to be well characterized. Here, we report a human lesion study (n = 149) that investigates the neural bases of key competencies of cognitive flexibility (i.e., mental flexibility and the fluent generation of new ideas) and systematically examine their contributions to a broad spectrum of cognitive and social processes, including psychometric intelligence (Wechsler Adult Intelligence Scale), emotional intelligence (Mayer, Salovey, Caruso Emotional Intelligence Test), and personality (Neuroticism–Extraversion–Openness Personality Inventory). Latent variable modeling was applied to obtain error-free indices of each factor, followed by voxel-based lesion-symptom mapping to elucidate their neural substrates. Regression analyses revealed that latent scores for psychometric intelligence reliably predict latent scores for cognitive flexibility (adjusted R2 = 0.94). Lesion mapping results further indicated that these convergent processes depend on a shared network of frontal, temporal, and parietal regions, including white matter association tracts, which bind these areas into an integrated system. A targeted analysis of the unique variance explained by cognitive flexibility further revealed selective damage within the right superior temporal gyrus, a region known to support insight and the recognition of novel semantic relations. The observed findings motivate an integrative framework for understanding the neural foundations of adaptive behavior, suggesting that core elements of cognitive flexibility emerge from a distributed network of brain regions that support specific competencies for human intelligence. PMID:23721727

Cognitive Styles in Admission Procedures for Assessing Candidates of Architecture

Science.gov (United States)

Casakin, Hernan; Gigi, Ariela

2016-01-01

Cognitive style has a strong predictive power in academic and professional success. This study investigated the cognitive profile of candidates studying architecture. Specifically, it explored the relation between visual and verbal cognitive styles, and the performance of candidates in admission procedures. The cognitive styles of candidates who…

Virtualized cognitive network architecture for 5G cellular networks

KAUST Repository

Elsawy, Hesham

2015-07-17

Cellular networks have preserved an application agnostic and base station (BS) centric architecture1 for decades. Network functionalities (e.g. user association) are decided and performed regardless of the underlying application (e.g. automation, tactile Internet, online gaming, multimedia). Such an ossified architecture imposes several hurdles against achieving the ambitious metrics of next generation cellular systems. This article first highlights the features and drawbacks of such architectural ossification. Then the article proposes a virtualized and cognitive network architecture, wherein network functionalities are implemented via software instances in the cloud, and the underlying architecture can adapt to the application of interest as well as to changes in channels and traffic conditions. The adaptation is done in terms of the network topology by manipulating connectivities and steering traffic via different paths, so as to attain the applications\\' requirements and network design objectives. The article presents cognitive strategies to implement some of the classical network functionalities, along with their related implementation challenges. The article further presents a case study illustrating the performance improvement of the proposed architecture as compared to conventional cellular networks, both in terms of outage probability and handover rate.

Hybrid Experiential-Heuristic Cognitive Radio Engine Architecture and Implementation

Directory of Open Access Journals (Sweden)

Ashwin Amanna

2012-01-01

Full Text Available The concept of cognitive radio (CR focuses on devices that can sense their environment, adapt configuration parameters, and learn from past behaviors. Architectures tend towards simplified decision-making algorithms inspired by human cognition. Initial works defined cognitive engines (CEs founded on heuristics, such as genetic algorithms (GAs, and case-based reasoning (CBR experiential learning algorithms. This hybrid architecture enables both long-term learning, faster decisions based on past experience, and capability to still adapt to new environments. This paper details an autonomous implementation of a hybrid CBR-GA CE architecture on a universal serial radio peripheral (USRP software-defined radio focused on link adaptation. Details include overall process flow, case base structure/retrieval method, estimation approach within the GA, and hardware-software lessons learned. Unique solutions to realizing the concept include mechanisms for combining vector distance and past fitness into an aggregate quantification of similarity. Over-the-air performance under several interference conditions is measured using signal-to-noise ratio, packet error rate, spectral efficiency, and throughput as observable metrics. Results indicate that the CE is successfully able to autonomously change transmit power, modulation/coding, and packet size to maintain the link while a non-cognitive approach loses connectivity. Solutions to existing shortcomings are proposed for improving case-base searching and performance estimation methods.

Impact of Cognitive Architectures on Human-Computer Interaction

Science.gov (United States)

2014-09-01

activation, reinforced learning, emotion, semantic memory , episodic memory , and visual imagery.12 In 2010 Rosenbloom created a variant of the Soar...being added to almost every new version. In 2004 Nuxoll and Laird added episodic memory to the Soar architecture.11 In 2008 Laird presented...York (NY): Psychology Press; 2014; p. 1–50. 11. Nuxoll A, Laird JE. A cognitive model of episodic memory integrated with a general cognitive

High Dynamic Range Cognitive Radio Front Ends: Architecture to Evaluation

Science.gov (United States)

Ashok, Arun; Subbiah, Iyappan; Varga, Gabor; Schrey, Moritz; Heinen, Stefan

2016-07-01

Advent of TV white space digitization has released frequencies from 470 MHz to 790 MHz to be utilized opportunistically. The secondary user can utilize these so called TV spaces in the absence of primary users. The most important challenge for this coexistence is mutual interference. While the strong TV stations can completely saturate the receiver of the cognitive radio (CR), the cognitive radio spurious tones can disturb other primary users and white space devices. The aim of this paper is to address the challenges for enabling cognitive radio applications in WLAN and LTE. In this process, architectural considerations for the design of cognitive radio front ends are discussed. With high-IF converters, faster and flexible implementation of CR enabled WLAN and LTE are shown. The effectiveness of the architecture is shown by evaluating the CR front ends for compliance of standards namely 802.11b/g (WLAN) and 3GPP TS 36.101 (LTE).

The GOES-R Product Generation Architecture

Science.gov (United States)

Dittberner, G. J.; Kalluri, S.; Hansen, D.; Weiner, A.; Tarpley, A.; Marley, S.

2011-12-01

The GOES-R system will substantially improve users' ability to succeed in their work by providing data with significantly enhanced instruments, higher resolution, much shorter relook times, and an increased number and diversity of products. The Product Generation architecture is designed to provide the computer and memory resources necessary to achieve the necessary latency and availability for these products. Over time, new and updated algorithms are expected to be added and old ones removed as science advances and new products are developed. The GOES-R GS architecture is being planned to maintain functionality so that when such changes are implemented, operational product generation will continue without interruption. The primary parts of the PG infrastructure are the Service Based Architecture (SBA) and the Data Fabric (DF). SBA is the middleware that encapsulates and manages science algorithms that generate products. It is divided into three parts, the Executive, which manages and configures the algorithm as a service, the Dispatcher, which provides data to the algorithm, and the Strategy, which determines when the algorithm can execute with the available data. SBA is a distributed architecture, with services connected to each other over a compute grid and is highly scalable. This plug-and-play architecture allows algorithms to be added, removed, or updated without affecting any other services or software currently running and producing data. Algorithms require product data from other algorithms, so a scalable and reliable messaging is necessary. The SBA uses the DF to provide this data communication layer between algorithms. The DF provides an abstract interface over a distributed and persistent multi-layered storage system (e.g., memory based caching above disk-based storage) and an event management system that allows event-driven algorithm services to know when instrument data are available and where they reside. Together, the SBA and the DF provide a

Cross-cultural regularities in the cognitive architecture of pride.

Science.gov (United States)

Sznycer, Daniel; Al-Shawaf, Laith; Bereby-Meyer, Yoella; Curry, Oliver Scott; De Smet, Delphine; Ermer, Elsa; Kim, Sangin; Kim, Sunhwa; Li, Norman P; Lopez Seal, Maria Florencia; McClung, Jennifer; O, Jiaqing; Ohtsubo, Yohsuke; Quillien, Tadeg; Schaub, Max; Sell, Aaron; van Leeuwen, Florian; Cosmides, Leda; Tooby, John

2017-02-21

Pride occurs in every known culture, appears early in development, is reliably triggered by achievements and formidability, and causes a characteristic display that is recognized everywhere. Here, we evaluate the theory that pride evolved to guide decisions relevant to pursuing actions that enhance valuation and respect for a person in the minds of others. By hypothesis, pride is a neurocomputational program tailored by selection to orchestrate cognition and behavior in the service of: ( i ) motivating the cost-effective pursuit of courses of action that would increase others' valuations and respect of the individual, ( ii ) motivating the advertisement of acts or characteristics whose recognition by others would lead them to enhance their evaluations of the individual, and ( iii ) mobilizing the individual to take advantage of the resulting enhanced social landscape. To modulate how much to invest in actions that might lead to enhanced evaluations by others, the pride system must forecast the magnitude of the evaluations the action would evoke in the audience and calibrate its activation proportionally. We tested this prediction in 16 countries across 4 continents ( n = 2,085), for 25 acts and traits. As predicted, the pride intensity for a given act or trait closely tracks the valuations of audiences, local (mean r = +0.82) and foreign (mean r = +0.75). This relationship is specific to pride and does not generalize to other positive emotions that coactivate with pride but lack its audience-recalibrating function.

The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort

Science.gov (United States)

Robinson, Elise B.; Kirby, Andrew; Ruparel, Kosha; Yang, Jian; McGrath, Lauren; Anttila, Verneri; Neale, Benjamin M.; Merikangas, Kathleen; Lehner, Thomas; Sleiman, Patrick M.A.; Daly, Mark J.; Gur, Ruben; Gur, Raquel; Hakonarson, Hakon

2014-01-01

The objective of this analysis was to examine the genetic architecture of diverse cognitive abilities in children and adolescents, including the magnitude of common genetic effects and patterns of shared and unique genetic influences. Subjects included 3,689 members of the Philadelphia Neurodevelopmental Cohort, a general population sample of ages 8-21 years who completed an extensive battery of cognitive tests. We used genome-wide complex trait analysis (GCTA) to estimate the SNP-based heritability of each domain, as well as the genetic correlation between all domains that showed significant genetic influence. Several of the individual domains suggested strong influence of common genetic variants (e.g. reading ability, h2g=0.43, p=4e-06; emotion identification, h2g=0.36, p=1e-05; verbal memory, h2g=0.24, p=0.005). The genetic correlations highlighted trait domains that are candidates for joint interrogation in future genetic studies (e.g. language reasoning and spatial reasoning, r(g)=0.72, p=0.007). These results can be used to structure future genetic and neuropsychiatric investigations of diverse cognitive abilities. PMID:25023143

Modeling Goal-Directed User Exploration in Human-Computer Interaction

Science.gov (United States)

2011-02-01

sculptures architecture Theater Musicians & Composers Cinema , Television, & Broadcasting Music Dance Musical Instruments” The text entered for the...Pirolli, Chen & Pitkow, 2001), Scent- based Navigation and Information Foraging in the ACT cognitive architecture 1.0 (SNIF-ACT 1.0; Pirolli & Fu...2003) is the first of two process models of Web navigation based on Information Foraging Theory and implemented in the ACT-R cognitive architecture

Developing a Psychologically Inspired Cognitive Architecture for Robotic Control: The Symbolic and Subsymbolic Robotic Intelligence Control System (SS-RICS

Directory of Open Access Journals (Sweden)

Troy Dale Kelley

2006-09-01

Full Text Available This paper describes the ongoing development of a robotic control architecture that was inspired by computational cognitive architectures from the discipline of cognitive psychology. The robotic control architecture combines symbolic and subsymbolic representations of knowledge into a unified control structure. The architecture is organized as a goal driven, serially executing, production system at the highest symbolic level; and a multiple algorithm, parallel executing, simple collection of algorithms at the lowest subsymbolic level. The goal is to create a system that will progress through the same cognitive developmental milestones as do human infants. Common robotics problems of localization, object recognition, and object permanence are addressed within the specified framework.

Developing a Psychologically Inspired Cognitive Architecture for Robotic Control: The Symbolic and Subsymbolic Robotic Intelligence Control System (SS-RICS

Directory of Open Access Journals (Sweden)

Troy Dale Kelley

2008-11-01

Full Text Available This paper describes the ongoing development of a robotic control architecture that was inspired by computational cognitive architectures from the discipline of cognitive psychology. The robotic control architecture combines symbolic and subsymbolic representations of knowledge into a unified control structure. The architecture is organized as a goal driven, serially executing, production system at the highest symbolic level; and a multiple algorithm, parallel executing, simple collection of algorithms at the lowest subsymbolic level. The goal is to create a system that will progress through the same cognitive developmental milestones as do human infants. Common robotics problems of localization, object recognition, and object permanence are addressed within the specified framework.

Dynamic Neural Fields as a Step Towards Cognitive Neuromorphic Architectures

Directory of Open Access Journals (Sweden)

Yulia eSandamirskaya

2014-01-01

Full Text Available Dynamic Field Theory (DFT is an established framework for modelling embodied cognition. In DFT, elementary cognitive functions such as memory formation, formation of grounded representations, attentional processes, decision making, adaptation, and learning emerge from neuronal dynamics. The basic computational element of this framework is a Dynamic Neural Field (DNF. Under constraints on the time-scale of the dynamics, the DNF is computationally equivalent to a soft winner-take-all (WTA network, which is considered one of the basic computational units in neuronal processing. Recently, it has been shown how a WTA network may be implemented in neuromorphic hardware, such as analogue Very Large Scale Integration (VLSI device. This paper leverages the relationship between DFT and soft WTA networks to systematically revise and integrate established DFT mechanisms that have previously been spread among different architectures. In addition, I also identify some novel computational and architectural mechanisms of DFT which may be implemented in neuromorphic VLSI devices using WTA networks as an intermediate computational layer. These specific mechanisms include the stabilization of working memory, the coupling of sensory systems to motor dynamics, intentionality, and autonomous learning. I further demonstrate how all these elements may be integrated into a unified architecture to generate behavior and autonomous learning.

Cognitive function and unsafe driving acts during an on-road test among community-dwelling older adults with cognitive impairments.

Science.gov (United States)

Hotta, Ryo; Makizako, Hyuma; Doi, Takehiko; Tsutsumimoto, Kota; Nakakubo, Sho; Makino, Keitaro; Shimada, Hiroyuki

2018-02-19

To examine the relationship between cognitive function and unsafe driving acts among community-dwelling older adults with cognitive impairments. Participants (n = 160) were older residents of Obu, Japan, aged ≥65 years with cognitive impairments. They regularly drove and were assessed for the number of unsafe driving acts without adequate verification during an on-road test. We also evaluated cognitive function (attention, executive function and processing speed). Other examined variables included demographics, driving characteristics and visual condition. Participants were classified into two groups according to the number of unsafe driving acts as follows: high group (≥4 unsafe driving acts) and low group (≤3 unsafe driving acts). The high group participants were older in age (P age (r = 0.396, P age group. Processing speed was associated with unsafe driving acts that became worse with increasing age. Future study will be required to longitudinally examine the influence of processing speed on traffic accidents for those with cognitive impairments. Geriatr Gerontol Int 2018; ••: ••-••. © 2018 Japan Geriatrics Society.

MF-CRA: Multi-Function Cognitive Radio Architecture for Space Communications, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — EpiSys Science, Inc. and University of Arizona propose to develop, implement, and demonstrate Multi-Function Cognitive Radio Architecture (MF-CRA) for Space...

A Knowledge Conversion Model Based on the Cognitive Load Theory for Architectural Design Education

Science.gov (United States)

Wu, Yun-Wu; Liao, Shin; Wen, Ming-Hui; Weng, Kuo-Hua

2017-01-01

The education of architectural design requires balanced curricular arrangements of respectively theoretical knowledge and practical skills to really help students build their knowledge structures, particularly helping them in solving the problems of cognitive load. The purpose of this study is to establish an architectural design knowledge…

Network architectures and protocols for the integration of ACTS and ISDN

Science.gov (United States)

Chitre, D. M.; Lowry, P. A.

1992-01-01

A close integration of satellite networks and the integrated services digital network (ISDN) is essential for satellite networks to carry ISDN traffic effectively. This also shows how a given (pre-ISDN) satellite network architecture can be enhanced to handle ISDN signaling and provide ISDN services. It also describes the functional architecture and high-level protocols that could be implemented in the NASA Advanced Communications Technology Satellite (ACTS) low burst rate communications system to provide ISDN services.

Beyond functional architecture in cognitive neuropsychology: a reply to Coltheart (2010).

Science.gov (United States)

Plaut, David C; Patterson, Karalyn

2010-01-01

We (Patterson & Plaut, 2009) argued that cognitive neuropsychology has had a limited impact on cognitive science due to a nearly exclusive reliance on (a) single-case studies, (b) dissociations in cognitive performance, and (c) shallow, box-and-arrow theorizing, and we advocated adopting a case-series methodology, considering associations as well as dissociations, and employing explicit computational modeling in studying "how the brain does its cognitive business." In reply, Coltheart (2010) claims that our concern is misplaced because cognitive neuropsychology is concerned only with studying the mind, in terms of its "functional architecture," without regard to how this is implemented in the brain. In this response, we do not dispute his characterization of cognitive neuropsychology as it has typically been practiced over the last 40 years, but we suggest that our understanding of brain structure and function has advanced to the point where studying the mind without regard to the brain is unwise and perpetuates the field's isolation. Copyright © 2009 Cognitive Science Society, Inc.

78 FR 59475 - Architectural Barriers Act Accessibility Guidelines; Outdoor Developed Areas

Science.gov (United States)

2013-09-26

... species; the environment; or archaeological, cultural, historical, or other significant natural features... participate in outdoor recreation activities with their families and friends. The benefits are difficult to... Architectural Barriers Act Guidelines by cross-referencing Appendices C and D.\\5\\ Since these [[Page 59479...

Associations of centrally acting ACE inhibitors with cognitive decline and survival in Alzheimer's disease.

Science.gov (United States)

Fazal, Karim; Perera, Gayan; Khondoker, Mizanur; Howard, Robert; Stewart, Robert

2017-07-01

Cognitive improvement has been reported in patients receiving centrally acting angiotensin-converting enzyme inhibitors (C-ACEIs). To compare cognitive decline and survival after diagnosis of Alzheimer's disease between people receiving C-ACEIs, non-centrally acting angiotensin-converting enzyme inhibitors (NC-ACEIs), and neither. Routine Mini-Mental State Examination (MMSE) scores were extracted in 5260 patients receiving acetylcholinesterase inhibitors and analysed against C-/NC-ACEI exposure at the time of Alzheimer's disease diagnosis. In the 9 months after Alzheimer's disease diagnosis, MMSE scores significantly increased by 0.72 and 0.19 points per year in patients on C-ACEIs and neither respectively, but deteriorated by 0.61 points per year in those on NC-ACEIs. There were no significant group differences in score trajectories from 9 to 36 months and no differences in survival. In people with Alzheimer's disease receiving acetylcholinesterase inhibitors, those also taking C-ACEIs had stronger initial improvement in cognitive function, but there was no evidence of longer-lasting influence on dementia progression. R.S. has received research funding from Pfizer, Lundbeck, Roche, Janssen and GlaxoSmithKline. © The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license.

Cognitive Dynamic Optical Networks

DEFF Research Database (Denmark)

de Miguel, Ignacio; Duran, Ramon J.; Jimenez, Tamara

2013-01-01

The use of cognition is a promising element for the control of heterogeneous optical networks. Not only are cognitive networks able to sense current network conditions and act according to them, but they also take into account the knowledge acquired through past experiences; that is, they include...... learning with the aim of improving performance. In this paper, we review the fundamentals of cognitive networks and focus on their application to the optical networking area. In particular, a number of cognitive network architectures proposed so far, as well as their associated supporting technologies......, are reviewed. Moreover, several applications, mainly developed in the framework of the EU FP7 Cognitive Heterogeneous Reconfigurable Optical Network (CHRON) project, are also described....

On Realism of Architectural Procedural Models

Czech Academy of Sciences Publication Activity Database

Beneš, J.; Kelly, T.; Děchtěrenko, Filip; Křivánek, J.; Müller, P.

2017-01-01

Roč. 36, č. 2 (2017), s. 225-234 ISSN 0167-7055 Grant - others:AV ČR(CZ) StrategieAV21/14 Program:StrategieAV Institutional support: RVO:68081740 Keywords : realism * procedural modeling * architecture Subject RIV: IN - Informatics, Computer Science OBOR OECD: Cognitive sciences Impact factor: 1.611, year: 2016

The NBS-LRR architectures of plant R-proteins and metazoan NLRs evolved in independent events.

Science.gov (United States)

Urbach, Jonathan M; Ausubel, Frederick M

2017-01-31

There are intriguing parallels between plants and animals, with respect to the structures of their innate immune receptors, that suggest universal principles of innate immunity. The cytosolic nucleotide binding site-leucine rich repeat (NBS-LRR) resistance proteins of plants (R-proteins) and the so-called NOD-like receptors of animals (NLRs) share a domain architecture that includes a STAND (signal transduction ATPases with numerous domains) family NTPase followed by a series of LRRs, suggesting inheritance from a common ancestor with that architecture. Focusing on the STAND NTPases of plant R-proteins, animal NLRs, and their homologs that represent the NB-ARC (nucleotide-binding adaptor shared by APAF-1, certain R gene products and CED-4) and NACHT (named for NAIP, CIIA, HET-E, and TEP1) subfamilies of the STAND NTPases, we analyzed the phylogenetic distribution of the NBS-LRR domain architecture, used maximum-likelihood methods to infer a phylogeny of the NTPase domains of R-proteins, and reconstructed the domain structure of the protein containing the common ancestor of the STAND NTPase domain of R-proteins and NLRs. Our analyses reject monophyly of plant R-proteins and NLRs and suggest that the protein containing the last common ancestor of the STAND NTPases of plant R-proteins and animal NLRs (and, by extension, all NB-ARC and NACHT domains) possessed a domain structure that included a STAND NTPase paired with a series of tetratricopeptide repeats. These analyses reject the hypothesis that the domain architecture of R-proteins and NLRs was inherited from a common ancestor and instead suggest the domain architecture evolved at least twice. It remains unclear whether the NBS-LRR architectures were innovations of plants and animals themselves or were acquired by one or both lineages through horizontal gene transfer.

Architectures, Concepts and Architectures for Service Oriented Computing : proceedings of the 1st International Workshop - ACT4SOC 2007

NARCIS (Netherlands)

van Sinderen, Marten J.; Unknown, [Unknown

2007-01-01

This volume contains the proceedings of the First International Workshop on Architectures, Concepts and Technologies for Service Oriented Computing (ACT4SOC 2007), held on July 22 in Barcelona, Spain, in conjunction with the Second International Conference on Software and Data Technologies (ICSOFT

Cognitive Architecture for Direction of Attention Founded on Subliminal Memory Searches, Pseudorandom and Nonstop

OpenAIRE

Burger, J. R.

2008-01-01

By way of explaining how a brain works logically, human associative memory is modeled with logical and memory neurons, corresponding to standard digital circuits. The resulting cognitive architecture incorporates basic psychological elements such as short term and long term memory. Novel to the architecture are memory searches using cues chosen pseudorandomly from short term memory. Recalls alternated with sensory images, many tens per second, are analyzed subliminally as an ongoing process, ...

The validity of the Addenbrooke's Cognitive Examination-Revised (ACE-R) in acute stroke.

Science.gov (United States)

Morris, Katie; Hacker, Vicki; Lincoln, Nadina Berrice

2012-01-01

The purpose was to examine the validity of the Addenbrooke's Cognitive Examination Revised (ACE-R) as a screening measure to detect cognitive impairment after stroke. Stroke patients in hospital were recruited and the ACE-R, which includes the Mini-Mental Status Examination (MMSE), was administered, followed by a battery of neuropsychological tests, which served as the 'gold standard' for classification of cognitive impairment. The diagnostic validity of the ACE-R was determined by ROC analysis. Of the 101 patients who completed the ACE-R, 61 also completed the neuropsychological assessment. Both the MMSE and the ACE-R were found to have inadequate diagnostic validity for the detection of overall cognitive impairment (MMSE AUC = 0.53, p > 0.05; ACE-R AUC = 0.53, p > 0.05). The ACE-R subscales predicted impairment in specific cognitive domains significantly better than chance; Visuospatial (AUC = 0.71, p cognitive functioning. The ACE-R was not a suitable measure to screen for overall cognitive impairment in acute stroke patients, but was able to detect impairment in visuospatial, attention and executive domains.

Artificial cognition architectures

CERN Document Server

Crowder, James A; Friess, Shelli A

2013-01-01

The goal of this book is to establish the foundation, principles, theory, and concepts that are the backbone of real, autonomous Artificial Intelligence. Presented here are some basic human intelligence concepts framed for Artificial Intelligence systems. These include concepts like Metacognition and Metamemory, along with architectural constructs for Artificial Intelligence versions of human brain functions like the prefrontal cortex. Also presented are possible hardware and software architectures that lend themselves to learning, reasoning, and self-evolution

The Addenbrooke's Cognitive Examination Revised (ACE-R): a brief cognitive test battery for dementia screening.

Science.gov (United States)

Mioshi, Eneida; Dawson, Kate; Mitchell, Joanna; Arnold, Robert; Hodges, John R

2006-11-01

There is a clear need for brief, but sensitive and specific, cognitive screening instruments as evidenced by the popularity of the Addenbrooke's Cognitive Examination (ACE). We aimed to validate an improved revision (the ACE-R) which incorporates five sub-domain scores (orientation/attention, memory, verbal fluency, language and visuo-spatial). Standard tests for evaluating dementia screening tests were applied. A total of 241 subjects participated in this study (Alzheimer's disease=67, frontotemporal dementia=55, dementia of Lewy Bodies=20; mild cognitive impairment-MCI=36; controls=63). Reliability of the ACE-R was very good (alpha coefficient=0.8). Correlation with the Clinical Dementia Scale was significant (r=-0.321, pcognitive dysfunction. Copyright (c) 2006 John Wiley & Sons, Ltd.

Reconfiguration of Brain Network Architectures between Resting-State and Complexity-Dependent Cognitive Reasoning.

Science.gov (United States)

Hearne, Luke J; Cocchi, Luca; Zalesky, Andrew; Mattingley, Jason B

2017-08-30

Our capacity for higher cognitive reasoning has a measurable limit. This limit is thought to arise from the brain's capacity to flexibly reconfigure interactions between spatially distributed networks. Recent work, however, has suggested that reconfigurations of task-related networks are modest when compared with intrinsic "resting-state" network architecture. Here we combined resting-state and task-driven functional magnetic resonance imaging to examine how flexible, task-specific reconfigurations associated with increasing reasoning demands are integrated within a stable intrinsic brain topology. Human participants (21 males and 28 females) underwent an initial resting-state scan, followed by a cognitive reasoning task involving different levels of complexity, followed by a second resting-state scan. The reasoning task required participants to deduce the identity of a missing element in a 4 × 4 matrix, and item difficulty was scaled parametrically as determined by relational complexity theory. Analyses revealed that external task engagement was characterized by a significant change in functional brain modules. Specifically, resting-state and null-task demand conditions were associated with more segregated brain-network topology, whereas increases in reasoning complexity resulted in merging of resting-state modules. Further increments in task complexity did not change the established modular architecture, but affected selective patterns of connectivity between frontoparietal, subcortical, cingulo-opercular, and default-mode networks. Larger increases in network efficiency within the newly established task modules were associated with higher reasoning accuracy. Our results shed light on the network architectures that underlie external task engagement, and highlight selective changes in brain connectivity supporting increases in task complexity. SIGNIFICANCE STATEMENT Humans have clear limits in their ability to solve complex reasoning problems. It is thought that

MEDIATING COGNITIVE TRANSFORMATION WITH VR 3D SKETCHING DURING CONCEPTUAL ARCHITECTURAL DESIGN PROCESS

Directory of Open Access Journals (Sweden)

Farzad Pour Rahimian

2011-03-01

Full Text Available Communications for information synchronization during the conceptual design phase require designers to employ more intuitive digital design tools. This paper presents findings of a feasibility study for using VR 3D sketching interface in order to replace current non-intuitive CAD tools. We used a sequential mixed method research methodology including a qualitative case study and a cognitive-based quantitative protocol analysis experiment. Foremost, the case study research was conducted in order to understand how novice designers make intuitive decisions. The case study documented the failure of conventional sketching methods in articulating complicated design ideas and shortcomings of current CAD tools in intuitive ideation. The case study’s findings then became the theoretical foundations for testing the feasibility of using VR 3D sketching interface during design. The latter phase of study evaluated the designers’ spatial cognition and collaboration at six different levels: "physical-actions", "perceptualactions", "functional-actions", "conceptual-actions", "cognitive synchronizations", and "gestures". The results and confirmed hypotheses showed that the utilized tangible 3D sketching interface improved novice designers’ cognitive and collaborative design activities. In summary this paper presents the influences of current external representation tools on designers’ cognition and collaboration as well as providing the necessary theoretical foundations for implementing VR 3D sketching interface. It contributes towards transforming conceptual architectural design phase from analogue to digital by proposing a new VR design interface. The paper proposes this transformation to fill in the existing gap between analogue conceptual architectural design process and remaining digital engineering parts of building design process hence expediting digital design process.

Production compilation : A simple mechanism to model complex skill acquisition

NARCIS (Netherlands)

Taatgen, N.A.; Lee, F.J.

2003-01-01

In this article we describe production compilation, a mechanism for modeling skill acquisition. Production compilation has been developed within the ACT-Rational (ACT-R; J. R. Anderson, D. Bothell, M. D. Byrne, & C. Lebiere, 2002) cognitive architecture and consists of combining and specializing

Cognitive architectures, rationality, and next-generation AI: a prolegomenon

Science.gov (United States)

Bello, Paul; Bringsjord, Selmer; Yang, Yingrui

2004-08-01

Computational models that give us insight into the behavior of individuals and the organizations to which they belong will be invaluable assets in our nation's war against terrorists, and state sponsorship of terror organizations. Reasoning and decision-making are essential ingredients in the formula for human cognition, yet the two have almost exclusively been studied in isolation from one another. While we have witnessed the emergence of strong traditions in both symbolic logic, and decision theory, we have yet to describe an acceptable interface between the two. Mathematical formulations of decision-making and reasoning have been developed extensively, but both fields make assumptions concerning human rationality that are untenable at best. True to this tradition, artificial intelligence has developed architectures for intelligent agents under these same assumptions. While these digital models of "cognition" tend to perform superbly, given their tremendous capacity for calculation, it is hardly reasonable to develop simulacra of human performance using these techniques. We will discuss some the challenges associated with the problem of developing integrated cognitive systems for use in modelling, simulation, and analysis, along with some ideas for the future.

In Situ Synthesis of Ag@Cu2O-rGO Architecture for Strong Light-Matter Interactions

Directory of Open Access Journals (Sweden)

Shuang Guo

2018-06-01

Full Text Available Emerging opportunities based on two-dimensional (2D layered structures can utilize a variety of complex geometric architectures. Herein, we report the synthesis and properties of a 2D+0D unique ternary platform-core-shell nanostructure, termed Ag@Cu2O-rGO, where the reduced graphene oxide (rGO 2D acting as a platform is uniformly decorated by Ag@Cu2O core-shell nanoparticles. Cu2O nanoparticles occupy the defect positions on the surface of the rGO platform and restore the conjugation of the rGO structure, which contributes to the significant decrease of the ID/IG intensity ratio. The rGO platform can not only bridge the isolated nanoparticles together but also can quickly transfer the free electrons arising from the Ag core to the Cu2O shell to improve the utilization efficiency of photogenerated electrons, as is verified by high efficient photocatalytic activity of Methyl Orange (MO. The multi-interface coupling of the Ag@Cu2O-rGO platform-core-shell nanostructure leads to the decrease of the bandgap with an increase of the Cu2O shell thickness, which broadens the absorption range of the visible light spectrum.

Long-Term Symbolic Learning

National Research Council Canada - National Science Library

Kennedy, William G; Trafton, J. G

2007-01-01

What are the characteristics of long-term learning? We investigated the characteristics of long-term, symbolic learning using the Soar and ACT-R cognitive architectures running cognitive models of two simple tasks...

Neonatal GLP1R activation limits adult adiposity by durably altering hypothalamic architecture

Directory of Open Access Journals (Sweden)

Andrea V. Rozo

2017-07-01

Conclusion: These observations suggest that the acute activation of GLP1R in neonates durably alters hypothalamic architecture to limit adult weight gain and adiposity, identifying GLP1R as a therapeutic target for obesity prevention.

A cognitive robotic system based on the Soar cognitive architecture for mobile robot navigation, search, and mapping missions

Science.gov (United States)

Hanford, Scott D.

Most unmanned vehicles used for civilian and military applications are remotely operated or are designed for specific applications. As these vehicles are used to perform more difficult missions or a larger number of missions in remote environments, there will be a great need for these vehicles to behave intelligently and autonomously. Cognitive architectures, computer programs that define mechanisms that are important for modeling and generating domain-independent intelligent behavior, have the potential for generating intelligent and autonomous behavior in unmanned vehicles. The research described in this presentation explored the use of the Soar cognitive architecture for cognitive robotics. The Cognitive Robotic System (CRS) has been developed to integrate software systems for motor control and sensor processing with Soar for unmanned vehicle control. The CRS has been tested using two mobile robot missions: outdoor navigation and search in an indoor environment. The use of the CRS for the outdoor navigation mission demonstrated that a Soar agent could autonomously navigate to a specified location while avoiding obstacles, including cul-de-sacs, with only a minimal amount of knowledge about the environment. While most systems use information from maps or long-range perceptual capabilities to avoid cul-de-sacs, a Soar agent in the CRS was able to recognize when a simple approach to avoiding obstacles was unsuccessful and switch to a different strategy for avoiding complex obstacles. During the indoor search mission, the CRS autonomously and intelligently searches a building for an object of interest and common intersection types. While searching the building, the Soar agent builds a topological map of the environment using information about the intersections the CRS detects. The agent uses this topological model (along with Soar's reasoning, planning, and learning mechanisms) to make intelligent decisions about how to effectively search the building. Once the

Integrated Cognitive-neuroscience Architectures for Understanding Sensemaking (ICArUS): Transition to the Intelligence Community

Science.gov (United States)

2014-12-01

Case Study P U Pc Pt Ft Pa 1 Clinical vs. Actuarial Geospatial Profiling Strategies X X 2 Route Security in Baghdad X X X X 3 International...Information Sciences , 176, 1570-1589. Burns, K., & Bonaceto, C. (2014). Integrated Cognitive-neuroscience Architectures for Understanding Sensemaking

Pre-attentive and attentive vision module

NARCIS (Netherlands)

Nyamsuren, Enkhbold; Taatgen, Niels A.

This paper introduces a new vision module, called PAAV, developed for the cognitive architecture ACT-R. Unlike ACT-R's default vision module that was originally developed for top-down perception only, PAAV was designed to model a wide range of tasks, such as visual search and scene viewing, where

A cognitive decision agent architecture for optimal energy management of microgrids

International Nuclear Information System (INIS)

Velik, Rosemarie; Nicolay, Pascal

2014-01-01

Highlights: • We propose an optimization approach for energy management in microgrids. • The optimizer emulates processes involved in human decision making. • Optimization objectives are energy self-consumption and financial gain maximization. • We gain improved optimization results in significantly reduced computation time. - Abstract: Via the integration of renewable energy and storage technologies, buildings have started to change from passive (electricity) consumers to active prosumer microgrids. Along with this development come a shift from centralized to distributed production and consumption models as well as discussions about the introduction of variable demand–supply-driven grid electricity prices. Together with upcoming ICT and automation technologies, these developments open space to a wide range of novel energy management and energy trading possibilities to optimally use available energy resources. However, what is considered as an optimal energy management and trading strategy heavily depends on the individual objectives and needs of a microgrid operator. Accordingly, elaborating the most suitable strategy for each particular system configuration and operator need can become quite a complex and time-consuming task, which can massively benefit from computational support. In this article, we introduce a bio-inspired cognitive decision agent architecture for optimized, goal-specific energy management in (interconnected) microgrids, which are additionally connected to the main electricity grid. For evaluating the performance of the architecture, a number of test cases are specified targeting objectives like local photovoltaic energy consumption maximization and financial gain maximization. Obtained outcomes are compared against a modified simulating annealing optimization approach in terms of objective achievement and computational effort. Results demonstrate that the cognitive decision agent architecture yields improved optimization results in

Enabling Technologies for Cognitive Optical Networks

DEFF Research Database (Denmark)

Borkowski, Robert

Cognition is a new paradigm for optical networking, in which the network has capabilities to observe, plan, decide, and act autonomously in order to optimize the end-to-end performance and minimize the need for human supervision. This PhD thesis expands the state of the art on cognitive optical......, and machine learning algorithms that make cognition possible. Secondly, advanced optical performance monitoring (OPM) capabilities performed via digital signal processing (DSP) that provide CONs with necessary feedback information allowing for autonomous network optimization. The research results presented...... in this thesis were carried out in the framework of the EU project Cognitive Heterogeneous Reconfigurable Optical Network (CHRON), whose aim was to develop an architecture and implement a testbed of a cognitive network able to self-configure and self-optimize to efficiently use available resources. In order...

MiR529a modulates panicle architecture through regulating SQUAMOSA PROMOTER BINDING-LIKE genes in rice (Oryza sativa).

Science.gov (United States)

Yue, Erkui; Li, Chao; Li, Yu; Liu, Zhen; Xu, Jian-Hong

2017-07-01

MiR529a affects rice panicle architecture by targeting OsSPL2,OsSPL14 and OsSPL17 genes that could regulate their downstream panicle related genes. The panicle architecture determines the grain yield and quality of rice, which could be regulated by many transcriptional factors. The SQUAMOSA PROMOTER BINDING-LIKE (SPL) transcription factors are involved in the regulation of panicle development, which are targeted by miR156 and miR529. The expression profile demonstrated that miR529a is preferentially expressed in the early panicle of rice and it might regulate panicle development in rice. However, the regulation mechanism of miR529-SPL is still not clear. In this study, we predicted five miR529a putative target genes, OsSPL2, OsSPL14, OsSPL16, OsSPL17 and OsSPL18, while only the expression of OsSPL2, OsSPL14, and OsSPL17 was regulated by miR529a in the rice panicle. Overexpression of miR529a dramatically affected panicle architecture, which was regulated by OsSPL2, OsSPL14, and OsSPL17. Furthermore, the 117, 35, and 25 pathway genes associated with OsSPL2, OsSPL14 and OsSPL17, respectively, were predicted, and they shared 20 putative pathway genes. Our results revealed that miR529a could play a vital role in the regulation of panicle architecture through regulating OsSPL2, OsSPL14, OsSPL17 and the complex networks formed by their pathway and downstream genes. These findings will provide new genetic resources for reshaping ideal plant architecture and breeding high yield rice varieties.

A Biologically Plausible Action Selection System for Cognitive Architectures: Implications of Basal Ganglia Anatomy for Learning and Decision-Making Models

Science.gov (United States)

Stocco, Andrea

2018-01-01

Several attempts have been made previously to provide a biological grounding for cognitive architectures by relating their components to the computations of specific brain circuits. Often, the architecture's action selection system is identified with the basal ganglia. However, this identification overlooks one of the most important features of…

Combining metric episodes with semantic event concepts within the Symbolic and Sub-Symbolic Robotics Intelligence Control System (SS-RICS)

Science.gov (United States)

Kelley, Troy D.; McGhee, S.

2013-05-01

This paper describes the ongoing development of a robotic control architecture that inspired by computational cognitive architectures from the discipline of cognitive psychology. The Symbolic and Sub-Symbolic Robotics Intelligence Control System (SS-RICS) combines symbolic and sub-symbolic representations of knowledge into a unified control architecture. The new architecture leverages previous work in cognitive architectures, specifically the development of the Adaptive Character of Thought-Rational (ACT-R) and Soar. This paper details current work on learning from episodes or events. The use of episodic memory as a learning mechanism has, until recently, been largely ignored by computational cognitive architectures. This paper details work on metric level episodic memory streams and methods for translating episodes into abstract schemas. The presentation will include research on learning through novelty and self generated feedback mechanisms for autonomous systems.

Agent Architectures for Compliance

Science.gov (United States)

Burgemeestre, Brigitte; Hulstijn, Joris; Tan, Yao-Hua

A Normative Multi-Agent System consists of autonomous agents who must comply with social norms. Different kinds of norms make different assumptions about the cognitive architecture of the agents. For example, a principle-based norm assumes that agents can reflect upon the consequences of their actions; a rule-based formulation only assumes that agents can avoid violations. In this paper we present several cognitive agent architectures for self-monitoring and compliance. We show how different assumptions about the cognitive architecture lead to different information needs when assessing compliance. The approach is validated with a case study of horizontal monitoring, an approach to corporate tax auditing recently introduced by the Dutch Customs and Tax Authority.

The architecture of ArgR-DNA complexes at the genome-scale in Escherichia coli

DEFF Research Database (Denmark)

Cho, Suhyung; Cho, Yoo-Bok; Kang, Taek Jin

2015-01-01

DNA-binding motifs that are recognized by transcription factors (TFs) have been well studied; however, challenges remain in determining the in vivo architecture of TF-DNA complexes on a genome-scale. Here, we determined the in vivo architecture of Escherichia coli arginine repressor (ArgR)-DNA co...

ADAPTING TO AND ADAPTED BY ADAPT-R - ARCHITECTURE, DESIGN AND ART PRACTICE TRAINING-RESEARCH

Directory of Open Access Journals (Sweden)

Johan Verbeke

2014-12-01

Full Text Available Recently Schools of Architecture have started paying much more attention to their research endeavors. Especially research by design is high on the agenda as well as research projects where experience and knowledge from creative practice plays a key role as a research method. This paper introduces the ADAPT-r project. The project acronym stands for Architecture, Design, Arts Practice training Research. ADAPT-r is funded under the 7th Framework of Research of the European Commission. The project partners stimulate and explore the potential of creative practice research . This paper reports on its setting and first experiences and results and tries to contribute to an ongoing debate and framing of the development.

Dual PECCS: a cognitive system for conceptual representation and categorization

Science.gov (United States)

Lieto, Antonio; Radicioni, Daniele P.; Rho, Valentina

2017-03-01

In this article we present an advanced version of Dual-PECCS, a cognitively-inspired knowledge representation and reasoning system aimed at extending the capabilities of artificial systems in conceptual categorization tasks. It combines different sorts of common-sense categorization (prototypical and exemplars-based categorization) with standard monotonic categorization procedures. These different types of inferential procedures are reconciled according to the tenets coming from the dual process theory of reasoning. On the other hand, from a representational perspective, the system relies on the hypothesis of conceptual structures represented as heterogeneous proxytypes. Dual-PECCS has been experimentally assessed in a task of conceptual categorization where a target concept illustrated by a simple common-sense linguistic description had to be identified by resorting to a mix of categorization strategies, and its output has been compared to human responses. The obtained results suggest that our approach can be beneficial to improve the representational and reasoning conceptual capabilities of standard cognitive artificial systems, and - in addition - that it may be plausibly applied to different general computational models of cognition. The current version of the system, in fact, extends our previous work, in that Dual- PECCS is now integrated and tested into two cognitive architectures, ACT-R and CLARION, implementing different assumptions on the underlying invariant structures governing human cognition. Such integration allowed us to extend our previous evaluation.

A framework for a architecture cognitive applied to the safety supervision in the nuclear power plant operation

International Nuclear Information System (INIS)

Souto, Kelling Cabral; Schirru, Roberto

2002-01-01

An architecture cognitive was developed as the start to the elaboration of a system for safety supervision. This architecture, that was made with a class of problem, was based in expert system theory. In this theory the inference motor is of the kind of backward chaining associated with a process of search in profundity and the representation of knowledge is based in rules that are grouped in a kind of grafo structure and include in the context of object orientation. A environment of test for this architecture was built to permit show its operation and in this way to indicate its potential utilization as basis for future nuclear power plant operation support systems. (author)

Brazilian adaptation of the Addenbrooke's Cognitive Examination-Revised (ACE-R

Directory of Open Access Journals (Sweden)

Viviane Amaral Carvalho

Full Text Available Abstract The Addenbrooke's Cognitive Examination-Revised (ACE-R is a highly sensitive and specific tool for the detection of mild dementia. It is particularly useful in differentiating Alzheimer's disease from frontotemporal dementia. While the first version of the test battery has been adapted in many countries, its revised version has not, probably because it was published very recently. Objective: To translate and adapt the ACE-R for use in the Brazilian population. Methods: Two independent translations were made from English into Portuguese, followed by two independent back-translations. Few adaptations in accordance to the Brazilian culture and language were made and a first version of the instrument produced. This former version of the ACE-R was administered to 21 cognitively healthy subjects aged 60 years or more, with different educational levels. Results: The mean age of the studied sample of healthy elderly was 75.4 years (ranging from 60 to 89 years. Small additional modifications were necessary after the evaluation of the first ten subjects in order to improve comprehension of the test. The final Portuguese version of the ACE-R was produced and was found to be well understood by the remaining 11 subjects, taking an average of 15 minutes to be administered. Conclusions: The Brazilian version of the ACE-R proved to be a promising cognitive instrument for testing both in research and clinical settings. With this regard, additional studies are currently being carried out in our unit in order to investigate the diagnostic properties of the ACE-R in our milieu.

Brazilian adaptation of the Addenbrooke's Cognitive Examination-Revised (ACE-R).

Science.gov (United States)

Carvalho, Viviane Amaral; Caramelli, Paulo

2007-01-01

The Addenbrooke's Cognitive Examination-Revised (ACE-R) is a highly sensitive and specific tool for the detection of mild dementia. It is particularly useful in differentiating Alzheimer's disease from frontotemporal dementia. While the first version of the test battery has been adapted in many countries, its revised version has not, probably because it was published very recently. To translate and adapt the ACE-R for use in the Brazilian population. Two independent translations were made from English into Portuguese, followed by two independent back-translations. Few adaptations in accordance to the Brazilian culture and language were made and a first version of the instrument produced. This former version of the ACE-R was administered to 21 cognitively healthy subjects aged 60 years or more, with different educational levels. The mean age of the studied sample of healthy elderly was 75.4 years (ranging from 60 to 89 years). Small additional modifications were necessary after the evaluation of the first ten subjects in order to improve comprehension of the test. The final Portuguese version of the ACE-R was produced and was found to be well understood by the remaining 11 subjects, taking an average of 15 minutes to be administered. The Brazilian version of the ACE-R proved to be a promising cognitive instrument for testing both in research and clinical settings. With this regard, additional studies are currently being carried out in our unit in order to investigate the diagnostic properties of the ACE-R in our milieu.

Cognitive wireless networks

CERN Document Server

Feng, Zhiyong; Zhang, Ping

2015-01-01

This brief examines the current research in cognitive wireless networks (CWNs). Along with a review of challenges in CWNs, this brief presents novel theoretical studies and architecture models for CWNs, advances in the cognitive information awareness and delivery, and intelligent resource management technologies. The brief presents the motivations and concepts of CWNs, including theoretical studies of temporal and geographic distribution entropy as well as cognitive information metrics. A new architecture model of CWNs is proposed with theoretical, functional and deployment architectures suppo

R2* mapping for brain iron: associations with cognition in normal aging.

Science.gov (United States)

Ghadery, Christine; Pirpamer, Lukas; Hofer, Edith; Langkammer, Christian; Petrovic, Katja; Loitfelder, Marisa; Schwingenschuh, Petra; Seiler, Stephan; Duering, Marco; Jouvent, Eric; Schmidt, Helena; Fazekas, Franz; Mangin, Jean-Francois; Chabriat, Hugues; Dichgans, Martin; Ropele, Stefan; Schmidt, Reinhold

2015-02-01

Brain iron accumulates during aging and has been associated with neurodegenerative disorders including Alzheimer's disease. Magnetic resonance (MR)-based R2* mapping enables the in vivo detection of iron content in brain tissue. We investigated if during normal brain aging iron load relates to cognitive impairment in region-specific patterns in a community-dwelling cohort of 336 healthy, middle aged, and older adults from the Austrian Stroke Prevention Family Study. MR imaging and R2* mapping in the basal ganglia and neocortex were done at 3T. Comprehensive neuropsychological testing assessed memory, executive function, and psychomotor speed. We found the highest iron concentration in the globus pallidus, and pallidal and putaminal iron was significantly and inversely associated with cognitive performance in all cognitive domains, except memory. These associations were iron load dependent. Vascular brain lesions and brain volume did not mediate the relationship between iron and cognitive performance. We conclude that higher R2*-determined iron in the basal ganglia correlates with cognitive impairment during brain aging independent of concomitant brain abnormalities. The prognostic significance of this finding needs to be determined. Copyright © 2015 Elsevier Inc. All rights reserved.

Genetic improvement of the shoot architecture and yield in soya bean plants via the manipulation of GmmiR156b.

Science.gov (United States)

Sun, Zhengxi; Su, Chao; Yun, Jinxia; Jiang, Qiong; Wang, Lixiang; Wang, Youning; Cao, Dong; Zhao, Fang; Zhao, Qingsong; Zhang, Mengchen; Zhou, Bin; Zhang, Lei; Kong, Fanjiang; Liu, Baohui; Tong, Yiping; Li, Xia

2018-05-05

The optimization of plant architecture in order to breed high-yielding soya bean cultivars is a goal of researchers. Tall plants bearing many long branches are desired, but only modest success in reaching these goals has been achieved. MicroRNA156 (miR156)-SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) gene modules play pivotal roles in controlling shoot architecture and other traits in crops like rice and wheat. However, the effects of miR156-SPL modules on soya bean architecture and yield, and the molecular mechanisms underlying these effects, remain largely unknown. In this study, we achieved substantial improvements in soya bean architecture and yield by overexpressing GmmiR156b. Transgenic plants produced significantly increased numbers of long branches, nodes and pods, and they exhibited an increased 100-seed weight, resulting in a 46%-63% increase in yield per plant. Intriguingly, GmmiR156b overexpression had no significant impact on plant height in a growth room or under field conditions; however, it increased stem thickness significantly. Our data indicate that GmmiR156b modulates these traits mainly via the direct cleavage of SPL transcripts. Moreover, we found that GmSPL9d is expressed in the shoot apical meristem and axillary meristems (AMs) of soya bean, and that GmSPL9d may regulate axillary bud formation and branching by physically interacting with the homeobox gene WUSCHEL (WUS), a central regulator of AM formation. Together, our results identify GmmiR156b as a promising target for the improvement of soya bean plant architecture and yields, and they reveal a new and conserved regulatory cascade involving miR156-SPL-WUS that will help researchers decipher the genetic basis of plant architecture. © 2018 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

Validation of the revised Addenbrooke's Cognitive Examination (ACE-R) for detecting mild cognitive impairment and dementia in a Japanese population.

Science.gov (United States)

Yoshida, Hidenori; Terada, Seishi; Honda, Hajime; Kishimoto, Yuki; Takeda, Naoya; Oshima, Etsuko; Hirayama, Keisuke; Yokota, Osamu; Uchitomi, Yosuke

2012-01-01

Early detection of dementia will be important for implementation of disease-modifying treatments in the near future. We aimed to investigate the diagnostic validity and reliability of the Japanese version of the revised Addenbrooke's Cognitive Examination (ACE-R J) for identifying mild cognitive impairment (MCI) and dementia. We translated and adapted the original ACE-R for use with a Japanese population. Standard tests for evaluating cognitive decline and dementing disorders were applied. A total of 242 subjects (controls = 73, MCI = 39, dementia = 130) participated in this study. The optimal cut-off scores of ACE-R J for detecting MCI and dementia were 88/89 (sensitivity 0.87, specificity 0.92) and 82/83 (sensitivity 0.99, specificity 0.99) respectively. ACE-R J was superior to the Mini-Mental State Examination in the detection of MCI (area under the curve (AUC): 0.952 vs. 0.868), while the accuracy of the two instruments did not differ significantly in identifying dementia (AUC: 0.999 vs. 0.993). The inter-rater reliability (ICC = 0.999), test-retest reliability (ICC = 0.883), and internal consistency (Cronbach's α = 0.903) of ACE-R J were excellent. ACE-R J proved to be an accurate cognitive instrument for detecting MCI and mild dementia. Further neuropsychological evaluation is required for the differential diagnosis of dementia subtypes.

Insights into Working Memory from The Perspective of The EPIC Architecture for Modeling Skilled Perceptual-Motor and Cognitive Human Performance

National Research Council Canada - National Science Library

Kieras, David

1998-01-01

Computational modeling of human perceptual-motor and cognitive performance based on a comprehensive detailed information- processing architecture leads to new insights about the components of working memory...

Preemptive Architecture: Explosive Art and Future Architectures in Cursed Urban Zones

Directory of Open Access Journals (Sweden)

Stahl Stenslie

2017-04-01

Full Text Available This article describes the art and architectural research project Preemptive Architecture that uses artistic strategies and approaches to create bomb-ready architectural structures that act as instruments for the undoing of violence in war. Increasing environmental usability through destruction represents an inverse strategy that reverses common thinking patterns about warfare, art and architecture. Building structures predestined for a construc­tive destruction becomes a creative act. One of the main motivations behind this paper is to challenge and expand the material thinking as well as the socio-political conditions related to artistic, architectural and design based practices.   Article received: December 12, 2016; Article accepted: January 10, 2017; Published online: April 20, 2017 Original scholarly paper How to cite this article: Stenslie, Stahl, and Magne Wiggen. "Preemptive Architecture: Explosive Art and Future Architectures in Cursed Urban Zones." AM Journal of Art and Media Studies 12 (2017: 29-39. doi: 10.25038/am.v0i12.165

Augmenting cognitive training in older adults (The ACT Study): Design and Methods of a Phase III tDCS and cognitive training trial.

Science.gov (United States)

Woods, Adam J; Cohen, Ronald; Marsiske, Michael; Alexander, Gene E; Czaja, Sara J; Wu, Samuel

2018-02-01

Adults over age 65 represent the fastest growing population in the US. Decline in cognitive abilities is a hallmark of advanced age and is associated with loss of independence and dementia risk. There is a pressing need to develop effective interventions for slowing or reversing the cognitive aging process. While certain forms of cognitive training have shown promise in this area, effects only sometimes transfer to neuropsychological tests within or outside the trained domain. This paper describes a NIA-funded Phase III adaptive multisite randomized clinical trial, examining whether transcranial direct current stimulation (tDCS) of frontal cortices enhances neurocognitive outcomes achieved from cognitive training in older adults experiencing age-related cognitive decline: the Augmenting Cognitive Training in Older Adults study (ACT). ACT will enroll 360 participants aged 65 to 89 with age-related cognitive decline, but not dementia. Participants will undergo cognitive training intervention or education training-control combined with tDCS or sham tDCS control. Cognitive training employs a suite of eight adaptive training tasks focused on attention/speed of processing and working memory from Posit Science BrainHQ. Training control involves exposure to educational nature/history videos and related content questions of the same interval/duration as the cognitive training. Participants are assessed at baseline, after training (12weeks), and 12-month follow-up on our primary outcome measure, NIH Toolbox Fluid Cognition Composite Score, as well as a comprehensive neurocognitive, functional, clinical and multimodal neuroimaging battery. The findings from this study have the potential to significantly enhance efforts to ameliorate cognitive aging and slow dementia. Copyright © 2017 Elsevier Inc. All rights reserved.

DigR: a generic model and its open source simulation software to mimic three-dimensional root-system architecture diversity.

Science.gov (United States)

Barczi, Jean-François; Rey, Hervé; Griffon, Sébastien; Jourdan, Christophe

2018-04-18

Many studies exist in the literature dealing with mathematical representations of root systems, categorized, for example, as pure structure description, partial derivative equations or functional-structural plant models. However, in these studies, root architecture modelling has seldom been carried out at the organ level with the inclusion of environmental influences that can be integrated into a whole plant characterization. We have conducted a multidisciplinary study on root systems including field observations, architectural analysis, and formal and mathematical modelling. This integrative and coherent approach leads to a generic model (DigR) and its software simulator. Architecture analysis applied to root systems helps at root type classification and architectural unit design for each species. Roots belonging to a particular type share dynamic and morphological characteristics which consist of topological and geometric features. The DigR simulator is integrated into the Xplo environment, with a user interface to input parameter values and make output ready for dynamic 3-D visualization, statistical analysis and saving to standard formats. DigR is simulated in a quasi-parallel computing algorithm and may be used either as a standalone tool or integrated into other simulation platforms. The software is open-source and free to download at http://amapstudio.cirad.fr/soft/xplo/download. DigR is based on three key points: (1) a root-system architectural analysis, (2) root type classification and modelling and (3) a restricted set of 23 root type parameters with flexible values indexed in terms of root position. Genericity and botanical accuracy of the model is demonstrated for growth, branching, mortality and reiteration processes, and for different root architectures. Plugin examples demonstrate the model's versatility at simulating plastic responses to environmental constraints. Outputs of the model include diverse root system structures such as tap

Using the ACT-R architecture to specify 39 quantitative process models of decision making

NARCIS (Netherlands)

Marewski, Julian N.; Mehlhorn, Katja

Hypotheses about decision processes are often formulated qualitatively and remain silent about the interplay of decision, memorial, and other cognitive processes. At the same time, existing decision models are specified at varying levels of detail, making it difficult to compare them. We provide a

Novel Radio Architectures for UWB, 60 GHz, and Cognitive Wireless Systems

Directory of Open Access Journals (Sweden)

Cabric Danijela

2006-01-01

Full Text Available There are several new radio systems which exploit novel strategies being made possible by the regulatory agencies to increase the availability of spectrum for wireless applications. Three of these that will be discussed are ultra-wideband (UWB, 60 GHz, and cognitive radios. The UWB approach attempts to share the spectrum with higher-priority users by transmitting at power levels that are so low that they do not cause interference. On the other hand, cognitive radios attempt to share spectra by introducing a spectrum sensing function, so that they are able to transmit in unused portions at a given time, place, and frequency. Another approach is to exploit the advances in CMOS technology to operate in frequency bands in the millimeter-wave region. 60 GHz operation is particularly attractive because of the 7 GHz of unlicensed spectrum that has been made available there. In this paper, we present an overview of novel radio architecture design approaches and address challenges dealing with high-frequencies, wide-bandwidths, and large dynamic-range signals encountered in these future wireless systems.

Brazilian adaptation of the Addenbrooke’s Cognitive Examination-Revised (ACE-R)

Science.gov (United States)

Carvalho, Viviane Amaral; Caramelli, Paulo

2007-01-01

The Addenbrooke’s Cognitive Examination-Revised (ACE-R) is a highly sensitive and specific tool for the detection of mild dementia. It is particularly useful in differentiating Alzheimer’s disease from frontotemporal dementia. While the first version of the test battery has been adapted in many countries, its revised version has not, probably because it was published very recently. Objective To translate and adapt the ACE-R for use in the Brazilian population. Methods Two independent translations were made from English into Portuguese, followed by two independent back-translations. Few adaptations in accordance to the Brazilian culture and language were made and a first version of the instrument produced. This former version of the ACE-R was administered to 21 cognitively healthy subjects aged 60 years or more, with different educational levels. Results The mean age of the studied sample of healthy elderly was 75.4 years (ranging from 60 to 89 years). Small additional modifications were necessary after the evaluation of the first ten subjects in order to improve comprehension of the test. The final Portuguese version of the ACE-R was produced and was found to be well understood by the remaining 11 subjects, taking an average of 15 minutes to be administered. Conclusions The Brazilian version of the ACE-R proved to be a promising cognitive instrument for testing both in research and clinical settings. With this regard, additional studies are currently being carried out in our unit in order to investigate the diagnostic properties of the ACE-R in our milieu. PMID:29213390

Grounded Object and Grasp Representations in a Cognitive Architecture

DEFF Research Database (Denmark)

Kraft, Dirk

developed. This work presents a system that is able to learn autonomously about objects and applicable grasps in an unknown environment through exploratory manipulation and to then use this grounded knowledge in a planning setup to address complex tasks. A set of different subsystems is needed to achieve....... The topics are ordered so that we proceed from the more general integration works towards the works describing the individual components. The first chapter gives an overview over the system that is able to learn a grounded visual object representation and a grounded grasp representation. In the following...... part, we describe how this grounding procedures can be embedded in a three cognitive level architecture. Our initial work to use a tactile sensor to enrichen the object representations as well as allow for more complex actions is presented here as well. Since our system is concerned with learning about...

Architectural communication: Intra and extra activity of architecture

Directory of Open Access Journals (Sweden)

Stamatović-Vučković Slavica

2013-01-01

Full Text Available Apart from a brief overview of architectural communication viewed from the standpoint of theory of information and semiotics, this paper contains two forms of dualistically viewed architectural communication. The duality denotation/connotation (”primary” and ”secondary” architectural communication is one of semiotic postulates taken from Umberto Eco who viewed architectural communication as a semiotic phenomenon. In addition, architectural communication can be viewed as an intra and an extra activity of architecture where the overall activity of the edifice performed through its spatial manifestation may be understood as an act of communication. In that respect, the activity may be perceived as the ”behavior of architecture”, which corresponds to Lefebvre’s production of space.

Hierarchical architecture of ReS_2/rGO composites with enhanced electrochemical properties for lithium-ion batteries

International Nuclear Information System (INIS)

Qi, Fei; Chen, Yuanfu; Zheng, Binjie; He, Jiarui; Li, Qian; Wang, Xinqiang; Lin, Jie; Zhou, Jinhao; Yu, Bo; Li, Pingjian; Zhang, Wanli

2017-01-01

Highlights: • The ReS_2/rGO composites have been synthesized by a facile one-pot method. • The ReS_2/rGO composites exhibit hierarchical architecture. • The ReS_2/rGO composites deliver better electrochemical performances than ReS_2. • The enhanced performance is due to porous and conductive structure of ReS_2/rGO. - Abstract: Rhenium disulfide (ReS_2), a two-dimensional (2D) semiconductor, has attracted more and more attention due to its unique anisotropic electronic, optical, mechanical properties. However, the facile synthesis and electrochemical property of ReS_2 and its composite are still necessary to be researched. In this study, for the first time, the ReS_2/reduced graphene oxide (rGO) composites have been synthesized through a facile and one-pot hydrothermal method. The ReS_2/rGO composites exhibit a hierarchical, interconnected, and porous architecture constructed by nanosheets. As anode for lithium-ion batteries, the as-synthesized ReS_2/rGO composites deliver a large initial capacity of 918 mAh g"−"1 at 0.2 C. In addition, the ReS_2/rGO composites exhibit much better electrochemical cycling stability and rate capability than that of bare ReS_2. The significant enhancement in electrochemical property can be attributed to its unique architecture constructed by nanosheets and porous structure, which can allow for easy electrolyte infiltration, efficient electron transfer, and ionic diffusion. Furthermore, the graphene with high electronic conductivity can provide good conductive passageways. The facile synthesis approach can be extended to prepare other 2D transition metal dichalcogenides semiconductors for energy storage and catalytic application.

Combining cognitive engineering and information fusion architectures to build effective joint systems

Science.gov (United States)

Sliva, Amy L.; Gorman, Joe; Voshell, Martin; Tittle, James; Bowman, Christopher

2016-05-01

The Dual Node Decision Wheels (DNDW) architecture concept was previously described as a novel approach toward integrating analytic and decision-making processes in joint human/automation systems in highly complex sociotechnical settings. In this paper, we extend the DNDW construct with a description of components in this framework, combining structures of the Dual Node Network (DNN) for Information Fusion and Resource Management with extensions on Rasmussen's Decision Ladder (DL) to provide guidance on constructing information systems that better serve decision-making support requirements. The DNN takes a component-centered approach to system design, decomposing each asset in terms of data inputs and outputs according to their roles and interactions in a fusion network. However, to ensure relevancy to and organizational fitment within command and control (C2) processes, principles from cognitive systems engineering emphasize that system design must take a human-centered systems view, integrating information needs and decision making requirements to drive the architecture design and capabilities of network assets. In the current work, we present an approach for structuring and assessing DNDW systems that uses a unique hybrid DNN top-down system design with a human-centered process design, combining DNN node decomposition with artifacts from cognitive analysis (i.e., system abstraction decomposition models, decision ladders) to provide work domain and task-level insights at different levels in an example intelligence, surveillance, and reconnaissance (ISR) system setting. This DNDW structure will ensure not only that the information fusion technologies and processes are structured effectively, but that the resulting information products will align with the requirements of human decision makers and be adaptable to different work settings .

Effects of Spatial Experiences & Cognitive Styles in the Solution Process of Space-Based Design Problems in the First Year of Architectural Design Education

Science.gov (United States)

Erkan Yazici, Yasemin

2013-01-01

There are many factors that influence designers in the architectural design process. Cognitive style, which varies according to the cognitive structure of persons, and spatial experience, which is created with spatial data acquired during life are two of these factors. Designers usually refer to their spatial experiences in order to find solutions…

Mario Becomes Cognitive.

Science.gov (United States)

Schrodt, Fabian; Kneissler, Jan; Ehrenfeld, Stephan; Butz, Martin V

2017-04-01

In line with Allen Newell's challenge to develop complete cognitive architectures, and motivated by a recent proposal for a unifying subsymbolic computational theory of cognition, we introduce the cognitive control architecture SEMLINCS. SEMLINCS models the development of an embodied cognitive agent that learns discrete production rule-like structures from its own, autonomously gathered, continuous sensorimotor experiences. Moreover, the agent uses the developing knowledge to plan and control environmental interactions in a versatile, goal-directed, and self-motivated manner. Thus, in contrast to several well-known symbolic cognitive architectures, SEMLINCS is not provided with production rules and the involved symbols, but it learns them. In this paper, the actual implementation of SEMLINCS causes learning and self-motivated, autonomous behavioral control of the game figure Mario in a clone of the computer game Super Mario Bros. Our evaluations highlight the successful development of behavioral versatility as well as the learning of suitable production rules and the involved symbols from sensorimotor experiences. Moreover, knowledge- and motivation-dependent individualizations of the agents' behavioral tendencies are shown. Finally, interaction sequences can be planned on the sensorimotor-grounded production rule level. Current limitations directly point toward the need for several further enhancements, which may be integrated into SEMLINCS in the near future. Overall, SEMLINCS may be viewed as an architecture that allows the functional and computational modeling of embodied cognitive development, whereby the current main focus lies on the development of production rules from sensorimotor experiences. Copyright © 2017 Cognitive Science Society, Inc.

A multimodal parallel architecture: A cognitive framework for multimodal interactions.

Science.gov (United States)

Cohn, Neil

2016-01-01

Human communication is naturally multimodal, and substantial focus has examined the semantic correspondences in speech-gesture and text-image relationships. However, visual narratives, like those in comics, provide an interesting challenge to multimodal communication because the words and/or images can guide the overall meaning, and both modalities can appear in complicated "grammatical" sequences: sentences use a syntactic structure and sequential images use a narrative structure. These dual structures create complexity beyond those typically addressed by theories of multimodality where only a single form uses combinatorial structure, and also poses challenges for models of the linguistic system that focus on single modalities. This paper outlines a broad theoretical framework for multimodal interactions by expanding on Jackendoff's (2002) parallel architecture for language. Multimodal interactions are characterized in terms of their component cognitive structures: whether a particular modality (verbal, bodily, visual) is present, whether it uses a grammatical structure (syntax, narrative), and whether it "dominates" the semantics of the overall expression. Altogether, this approach integrates multimodal interactions into an existing framework of language and cognition, and characterizes interactions between varying complexity in the verbal, bodily, and graphic domains. The resulting theoretical model presents an expanded consideration of the boundaries of the "linguistic" system and its involvement in multimodal interactions, with a framework that can benefit research on corpus analyses, experimentation, and the educational benefits of multimodality. Copyright © 2015.

Proceedings of KogWis 2010 : 10th Biannual Meeting of the German Society for Cognitive Science

OpenAIRE

2010-01-01

As the latest biannual meeting of the German Society for Cognitive Science (Gesellschaft für Kognitionswissenschaft, GK), KogWis 2010 at Potsdam University reflects the current trends in a fascinating domain of research concerned with human and artificial cognition and the interaction of mind and brain. The Plenary talks provide a venue for questions of the numerical capacities and human arithmetic (Brian Butterworth), of the theoretical development of cognitive architectures and intelligent ...

Systems architecture: a new model for sustainability and the built environment using nanotechnology, biotechnology, information technology, and cognitive science with living technology.

Science.gov (United States)

Armstrong, Rachel

2010-01-01

This report details a workshop held at the Bartlett School of Architecture, University College London, to initiate interdisciplinary collaborations for the practice of systems architecture, which is a new model for the generation of sustainable architecture that combines the discipline of the study of the built environment with the scientific study of complexity, or systems science, and adopts the perspective of systems theory. Systems architecture offers new perspectives on the organization of the built environment that enable architects to consider architecture as a series of interconnected networks with embedded links into natural systems. The public workshop brought together architects and scientists working with the convergence of nanotechnology, biotechnology, information technology, and cognitive science and with living technology to investigate the possibility of a new generation of smart materials that are implied by this approach.

A self-organized internal models architecture for coding sensory-motor schemes

Directory of Open Access Journals (Sweden)

Esaú eEscobar Juárez

2016-04-01

Full Text Available Cognitive robotics research draws inspiration from theories and models on cognition, as conceived by neuroscience or cognitive psychology, to investigate biologically plausible computational models in artificial agents. In this field, the theoretical framework of Grounded Cognition provides epistemological and methodological grounds for the computational modeling of cognition. It has been stressed in the literature that textit{simulation}, textit{prediction}, and textit{multi-modal integration} are key aspects of cognition and that computational architectures capable of putting them into play in a biologically plausible way are a necessity.Research in this direction has brought extensive empirical evidencesuggesting that textit{Internal Models} are suitable mechanisms forsensory-motor integration. However, current Internal Models architectures show several drawbacks, mainly due to the lack of a unified substrate allowing for a true sensory-motor integration space, enabling flexible and scalable ways to model cognition under the embodiment hypothesis constraints.We propose the Self-Organized Internal ModelsArchitecture (SOIMA, a computational cognitive architecture coded by means of a network of self-organized maps, implementing coupled internal models that allow modeling multi-modal sensory-motor schemes. Our approach addresses integrally the issues of current implementations of Internal Models.We discuss the design and features of the architecture, and provide empirical results on a humanoid robot that demonstrate the benefits and potentialities of the SOIMA concept for studying cognition in artificial agents.

A cognitive model for software architecture complexity

NARCIS (Netherlands)

Bouwers, E.; Lilienthal, C.; Visser, J.; Van Deursen, A.

2010-01-01

Evaluating the complexity of the architecture of a softwaresystem is a difficult task. Many aspects have to be considered to come to a balanced assessment. Several architecture evaluation methods have been proposed, but very few define a quality model to be used during the evaluation process. In

Invisible Elderly in Danish and Swedish Residential Care Home Architecture

DEFF Research Database (Denmark)

E Andersson, Jonas; Grangaard, Sidse

2015-01-01

This study of two architectural competitions suggests that the fit between architectural design and older users, who depend on regular caregiving due to cognitive or functional disabilities, requires a particular consideration when designing new residential care homes.......This study of two architectural competitions suggests that the fit between architectural design and older users, who depend on regular caregiving due to cognitive or functional disabilities, requires a particular consideration when designing new residential care homes....

Hierarchical architecture of ReS{sub 2}/rGO composites with enhanced electrochemical properties for lithium-ion batteries

Energy Technology Data Exchange (ETDEWEB)

Qi, Fei; Chen, Yuanfu, E-mail: yfchen@uestc.edu.cn; Zheng, Binjie; He, Jiarui; Li, Qian; Wang, Xinqiang; Lin, Jie; Zhou, Jinhao; Yu, Bo; Li, Pingjian; Zhang, Wanli

2017-08-15

Highlights: • The ReS{sub 2}/rGO composites have been synthesized by a facile one-pot method. • The ReS{sub 2}/rGO composites exhibit hierarchical architecture. • The ReS{sub 2}/rGO composites deliver better electrochemical performances than ReS{sub 2}. • The enhanced performance is due to porous and conductive structure of ReS{sub 2}/rGO. - Abstract: Rhenium disulfide (ReS{sub 2}), a two-dimensional (2D) semiconductor, has attracted more and more attention due to its unique anisotropic electronic, optical, mechanical properties. However, the facile synthesis and electrochemical property of ReS{sub 2} and its composite are still necessary to be researched. In this study, for the first time, the ReS{sub 2}/reduced graphene oxide (rGO) composites have been synthesized through a facile and one-pot hydrothermal method. The ReS{sub 2}/rGO composites exhibit a hierarchical, interconnected, and porous architecture constructed by nanosheets. As anode for lithium-ion batteries, the as-synthesized ReS{sub 2}/rGO composites deliver a large initial capacity of 918 mAh g{sup −1} at 0.2 C. In addition, the ReS{sub 2}/rGO composites exhibit much better electrochemical cycling stability and rate capability than that of bare ReS{sub 2}. The significant enhancement in electrochemical property can be attributed to its unique architecture constructed by nanosheets and porous structure, which can allow for easy electrolyte infiltration, efficient electron transfer, and ionic diffusion. Furthermore, the graphene with high electronic conductivity can provide good conductive passageways. The facile synthesis approach can be extended to prepare other 2D transition metal dichalcogenides semiconductors for energy storage and catalytic application.

An Embodied Architecture

Directory of Open Access Journals (Sweden)

Frances Downing

2012-10-01

Full Text Available An architecture of the body is emerging out of theories of biology, complexity, and systems through the use of an evolving organism as its metaphor. Autopoiesis is the term used by biologists to describe the realm of existence for a living organism as it slides between the interchange of structure and information. Incoming information is filtered through the organism for its usefulness in the art of staying alive. Structural or organizational changes evolve as the organism adjusts to new information. To remain a viable organism—to survive—means that an entity must keep evolving without surrendering identity. Humans must maintain an embodied identity, often referred to as an organized self (Maturana & Varela, 1980, 1987, while viably exchanging information with other entities and the environment. This operation creates a topological boundary across which the communication takes place. Cognitive theorists and researchers have proposed that the animal condition is one of Embodied Realism; that is, animals such as we humans, are embodied, using our bodies to create basic metaphors, and, that we do this in a“real” world. The role of cognition in this equation is to allow humans the use of embodiment to explore abstract ideas through metaphor—such as “grasping an idea” (Lakoff &Johnson, 2003. In doing so, it allows the invention of an evolving language that refers to things “outside” our skin,like other entities and places. Autopoiesis describes the activities at the “edge” or boundary of an organism. The linguistic act can, therefore, be identified as fundamental medium for communication in the edge, between inside and outside, that assures the autopoiesis of place.In our own bodies, flesh is the biological manifest of the edge or boundary condition. Our understanding of flesh is that it is another of our organs; and at the same time, all organs are also bounded by flesh. It serves as a porous filter, delicate and complicated�

Bruxism in children: effect on sleep architecture and daytime cognitive performance and behavior.

Science.gov (United States)

Herrera, Marcela; Valencia, Ignacio; Grant, Mitzie; Metroka, David; Chialastri, Augustine; Kothare, Sanjeev V

2006-09-01

Sleep bruxism is an involuntary mandibular movement with tooth grinding during sleep. The prevalence of sleep bruxism in children is high and may lead to frequent arousals with altered daytime functioning. We investigated the sleep architecture, the incidence of gastroesophageal reflux, and the daytime cognitive behavioral functioning in a group of children with sleep bruxism. DESIGN-PATIENTS: This prospective pilot study included 10 children. Polysomnographic data with pH-probe analysis was compared with 10 age- and sex-matched controls. Each patient completed a dental evaluation, a nighttime polysomnogram, and cognitive behavioral tests (Kaufman Brief Intelligence Test and Achenbach Child Behavior Checklist). Eight of 10 children had clinically significant bruxism and the 2 remaining patients had recent teeth exfoliation. There was no difference on sleep architecture between patients and controls, except for a higher arousal index for the bruxism group (36.7 vs 20.7, p Sleep bruxism occurred more frequently in stage 2 and rapid eye movement sleep, with arousals in 66% of the cases. There was no relationship of bruxism to gastroesophageal reflux or intelligence. However, 40% of the patients had elevated scores on the Achenbach Child Behavior Checklist, indicating significant attention and behavior problems, and there were moderate correlations between the arousal index and several of the behavior-problem scales from the Achenbach Child Behavior Checklist (0.5 to 0.6). The data suggest that children with bruxism have a higher arousal index, which may be associated with an increased incidence of attention-behavior problems. Future studies investigating pediatric sleep bruxism will need to focus on behavior issues that may be prevalent in this population.

A Functional Model of Sensemaking in a Neurocognitive Architecture (Open Access, Publisher’s Version)

Science.gov (United States)

2013-07-08

updating processes involved in sensemaking. We do this by developing ACT-R models to specify how ele- mentary cognitive modules and processes are marshaled ...13] M. I. Posner, R. Goldsmith , and K. E. Welton Jr., “Perceived distance and the classification of distorted patterns,” Journal of Experimental

Simulating motivated cognition

Science.gov (United States)

Gevarter, William B.

1991-01-01

A research effort to develop a sophisticated computer model of human behavior is described. A computer framework of motivated cognition was developed. Motivated cognition focuses on the motivations or affects that provide the context and drive in human cognition and decision making. A conceptual architecture of the human decision-making approach from the perspective of information processing in the human brain is developed in diagrammatic form. A preliminary version of such a diagram is presented. This architecture is then used as a vehicle for successfully constructing a computer program simulation Dweck and Leggett's findings that relate how an individual's implicit theories orient them toward particular goals, with resultant cognitions, affects, and behavior.

Delivering Training Assessments in a Soldier Centered Learning Environment: Year One

Science.gov (United States)

2014-09-01

virtual classroom in comparison to the mobile training. Social cognitive theory (see Bandura , 1986) would support the idea that creating a social ...R. (1996). ACT: A simple theory of complex cognition. American Psychologist, 51(4), 355-365. Bandura , A. (1986). Social foundations of thought...architecture that would allow timely feedback with customizable levels of specificity necessitates a time investment and requires expertise in learning theory

Validation of the Spanish Version of the Addenbrooke's Cognitive Examination-Revised (ACE-R).

Science.gov (United States)

Torralva, T; Roca, M; Gleichgerrcht, E; Bonifacio, A; Raimondi, C; Manes, F

2011-01-01

The Addenbrooke's Cognitive Examination Revised (ACE-R) is an improved version of the earlier brief screening test which has been validated in English with high sensitivity and specificity to detect cognitive dysfunction. The aim of this study was to validate the Spanish version of the ACE-R in an Argentine population. A group of patients with Alzheimer Disease (AD) and patients with behavioural variant Frontotemporal Dementia (bvFTD) paired by age, sex, and years of education with healthy controls were assessed using the ACE-R. Stage of dementia was measured with the Clinical Dementia Rating Scale (CDR). The English version of the ACE-R was first translated into Spanish and then back-translated into English by two blind independent experts. Internal reliability was very good (Cronbach's alpha=0.89). Concurrent validity, determined by the correlation between total ACE-R and CDR was significant (Pcognitive impairment and has shown to discriminate between bvFTD and AD. Copyright © 2010 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

Computational cognitive modeling of the temporal dynamics of fatigue from sleep loss.

Science.gov (United States)

Walsh, Matthew M; Gunzelmann, Glenn; Van Dongen, Hans P A

2017-12-01

Computational models have become common tools in psychology. They provide quantitative instantiations of theories that seek to explain the functioning of the human mind. In this paper, we focus on identifying deep theoretical similarities between two very different models. Both models are concerned with how fatigue from sleep loss impacts cognitive processing. The first is based on the diffusion model and posits that fatigue decreases the drift rate of the diffusion process. The second is based on the Adaptive Control of Thought - Rational (ACT-R) cognitive architecture and posits that fatigue decreases the utility of candidate actions leading to microlapses in cognitive processing. A biomathematical model of fatigue is used to control drift rate in the first account and utility in the second. We investigated the predicted response time distributions of these two integrated computational cognitive models for performance on a psychomotor vigilance test under conditions of total sleep deprivation, simulated shift work, and sustained sleep restriction. The models generated equivalent predictions of response time distributions with excellent goodness-of-fit to the human data. More importantly, although the accounts involve different modeling approaches and levels of abstraction, they represent the effects of fatigue in a functionally equivalent way: in both, fatigue decreases the signal-to-noise ratio in decision processes and decreases response inhibition. This convergence suggests that sleep loss impairs psychomotor vigilance performance through degradation of the quality of cognitive processing, which provides a foundation for systematic investigation of the effects of sleep loss on other aspects of cognition. Our findings illustrate the value of treating different modeling formalisms as vehicles for discovery.

Performance of low-educated elders with depression on Addenbrooke's Cognitive Examination-Revised (ace-r test

Directory of Open Access Journals (Sweden)

Michele Beckert

Full Text Available Along with cognitive disorders, depression has been a concern for mental health services due to its highly debilitating effect on the functioning and quality of life of the elderly. However, there is still little understanding of the cognitive alterations resulting from depression or of the difficult differential diagnosis with mild cognitive impairment (MCI. It is known that performance on cognitive tests is strongly influenced by education but few studies have been conducted involving low-educated populations. Objective : To evaluate the performance of elders with low education and no dementia on Addenbrooke's Cognitive Examination-Revised (ACE-R test and its cognitive domains, and compare patients with Current Major Depressive Episode (CMDE against those without depressive symptoms. Methods : A retrospective, cross-sectional analytical study was conducted based on medical files of patients treated at the Cerebral Aging Clinic of the Hospital São Lucas of the PUCRS. The study included 116 individuals with low education (< 8 years of education aged between 60 and 84 (69.6 ± 6.4 years, with MCDE (N = 41 and controls (N = 75. Results : No significant difference was observed between control and MCDE groups in median scores on the ACE-R, Mini-Mental State Examination, and the five cognitive domains. There was also no difference between the groups on separate analyses of results on the clock drawing test, the categorical verbal and phonological fluency test, and the naming test. Conclusion : The results of this study showed that depressive symptoms did not influence scores on the ACE-R tests conducted in elders with low education.

FroboMind, proposing a conceptual architecture for agricultural field robot navigation

DEFF Research Database (Denmark)

Jensen, Kjeld; Bøgild, Anders; Nielsen, Søren Hundevadt

2011-01-01

The aim of this work is to propose a conceptual system architecture Field Robot Cognitive System Architecture (FroboMind). which can provide the flexibility and extend ability required for further research and development within cognition based navigation of plant nursing robots....

The Addenbrooke's Cognitive Examination Revised (ACE-R) and its sub-scores: normative values in an Italian population sample.

Science.gov (United States)

Siciliano, Mattia; Raimo, Simona; Tufano, Dario; Basile, Giuseppe; Grossi, Dario; Santangelo, Franco; Trojano, Luigi; Santangelo, Gabriella

2016-03-01

The Addenbrooke's Cognitive Examination Revised (ACE-R) is a rapid screening battery, including five sub-scales to explore different cognitive domains: attention/orientation, memory, fluency, language and visuospatial. ACE-R is considered useful in discriminating cognitively normal subjects from patients with mild dementia. The aim of present study was to provide normative values for ACE-R total score and sub-scale scores in a large sample of Italian healthy subjects. Five hundred twenty-six Italian healthy subjects (282 women and 246 men) of different ages (age range 20-93 years) and educational level (from primary school to university) underwent ACE-R and Montreal Cognitive Assessment (MoCA). Multiple linear regression analysis revealed that age and education significantly influenced performance on ACE-R total score and sub-scale scores. A significant effect of gender was found only in sub-scale attention/orientation. From the derived linear equation, a correction grid for raw scores was built. Inferential cut-offs score were estimated using a non-parametric technique and equivalent scores (ES) were computed. Correlation analysis showed a good significant correlation between ACE-R adjusted scores with MoCA adjusted scores (r = 0.612, p < 0.001). The present study provided normative data for the ACE-R in an Italian population useful for both clinical and research purposes.

The Spanish version of the Addenbrooke's Cognitive Examination - Revised (ACE-R) in subcortical ischemic vascular dementia.

Science.gov (United States)

Raimondi, Catalina; Gleichgerrcht, Ezequiel; Richly, Pablo; Torralva, Teresa; Roca, María; Camino, Julieta; Manes, Facundo

2012-11-15

Vascular dementia (VaD) is one of the most prevalent causes of dementia, and it is frequently misdiagnosed and undertreated in clinical practice. Because neuropsychological outcome depends, among other factors, on the size and location of the vascular brain injury, characterizing the cognitive profile of VaD has been especially challenging. Yet, there has been sufficient evidence to show a marked impairment of attention and executive functions, in particular in relation to Alzheimer disease. Being able to detect these deficits at bedside is crucial for everyday clinical practice, and yet, brief cognitive screening toots such as the Mini-Mental Sate Examination (MMSE) may overlook at cognitive deficits typical of patients with VaD. The Addenbrooke's Cognitive Examination Revised (ACE-R) is also a brief cognitive screening tool designed to incorporate the items of the MMSE and further extend the test to assess orientation, attention, verbal fluency, memory, language, and visuospatial abilities. In this study, we investigated the ability of the Spanish version of the ACE-R to detect the cognitive impairment showed in patients with subcortical ischemic vascular dementia, and we compared its usefulness to that of the MMSE in this population. Scores on these tests were compared to those of patients with Alzheimer disease and matched healthy controls. The 88-point cut-off proposed for the ACE-R was associated with a sensitivity of 100% and a specificity of 100% for the detection of cognitive impairment, demonstrating a stronger capacity than the MMSE (sensitivity of 42% with its 23-point cut-off score). We also found that the verbal fluency subtest of the ACE-R may be potentially useful in discriminating patients with subcortical ischemic vascular dementia from patients with AD. We discuss the utility of these findings in the context of everyday clinical practice and we propose that future studies should evaluate the potential usefulness of combining the ACE-R with a

The cognition-enhancing activity of E1R, a novel positive allosteric modulator of sigma-1 receptors

Science.gov (United States)

Zvejniece, L; Vavers, E; Svalbe, B; Vilskersts, R; Domracheva, I; Vorona, M; Veinberg, G; Misane, I; Stonans, I; Kalvinsh, I; Dambrova, M

2014-01-01

Background and Purpose Here, we describe the in vitro and in vivo effects of (4R,5S)-2-(5-methyl-2-oxo-4-phenyl-pyrrolidin-1-yl)-acetamide (E1R), a novel positive allosteric modulator of sigma-1 receptors. Experimental Approach E1R was tested for sigma receptor binding activity in a [3H](+)-pentazocine assay, in bradykinin (BK)-induced intracellular Ca2+ concentration ([Ca2+]i) assays and in an electrically stimulated rat vas deferens model. E1R's effects on cognitive function were tested using passive avoidance (PA) and Y-maze tests in mice. A selective sigma-1 receptor antagonist (NE-100), was used to study the involvement of the sigma-1 receptor in the effects of E1R. The open-field test was used to detect the effects of E1R on locomotion. Key Results Pretreatment with E1R enhanced the selective sigma-1 receptor agonist PRE-084's stimulating effect during a model study employing electrically stimulated rat vasa deferentia and an assay measuring the BK-induced [Ca2+]i increase. Pretreatment with E1R facilitated PA retention in a dose-related manner. Furthermore, E1R alleviated the scopolamine-induced cognitive impairment during the PA and Y-maze tests in mice. The in vivo and in vitro effects of E1R were blocked by treatment with the selective sigma-1 receptor antagonist NE-100. E1R did not affect locomotor activity. Conclusion and Implications E1R is a novel 4,5-disubstituted derivative of piracetam that enhances cognition and demonstrates efficacy against scopolamine-induced cholinergic dysfunction in mice. These effects are attributed to its positive modulatory action on the sigma-1 receptor and this activity may be relevant when developing new drugs for treating cognitive symptoms related to neurodegenerative diseases. PMID:24490863

Performance of low-educated elders with depression on Addenbrooke's Cognitive Examination-Revised (ace-r) test.

Science.gov (United States)

Beckert, Michele; Loureiro, Fernanda; Menta, Caroline; Mello, Elisa Fasolin; Nogueira, Eduardo L; von Gunten, Armin; Gomes, Irênio

2016-01-01

Along with cognitive disorders, depression has been a concern for mental health services due to its highly debilitating effect on the functioning and quality of life of the elderly. However, there is still little understanding of the cognitive alterations resulting from depression or of the difficult differential diagnosis with mild cognitive impairment (MCI). It is known that performance on cognitive tests is strongly influenced by education but few studies have been conducted involving low-educated populations. To evaluate the performance of elders with low education and no dementia on Addenbrooke's Cognitive Examination-Revised (ACE-R) test and its cognitive domains, and compare patients with Current Major Depressive Episode (CMDE) against those without depressive symptoms. A retrospective, cross-sectional analytical study was conducted based on medical files of patients treated at the Cerebral Aging Clinic of the Hospital São Lucas of the PUCRS. The study included 116 individuals with low education (Examination, and the five cognitive domains. There was also no difference between the groups on separate analyses of results on the clock drawing test, the categorical verbal and phonological fluency test, and the naming test. The results of this study showed that depressive symptoms did not influence scores on the ACE-R tests conducted in elders with low education.

Strategy and pattern recognition in expert\\ud comprehension of 2 × 2 interaction graphs

OpenAIRE

Peebles, David

2013-01-01

I present a model of expert comprehension performance for 2 × 2 "interaction" graphs typically used to present data from two-way factorial research designs. Developed using the ACT-R cognitive architecture, the model simulates the cognitive and perceptual operations involved in interpreting interaction graphs and provides a detailed characterisation of the information\\ud extracted from the diagram, the prior knowledge required to interpret interaction graphs, and the knowledge generated durin...

Risk Management Programs under Clean Air Act Section 112(r): Guidance for Implementing Agencies

Science.gov (United States)

Accidental release prevention programs under section 112(r) of the Clean Air Act (CAA) are related to and build on activities under the Emergency Planning and Community Right-to-Know Act, and Occupational Safety and Health Administration standards.

R-GPU : A reconfigurable GPU architecture

NARCIS (Netherlands)

van den Braak, G.J.; Corporaal, H.

2016-01-01

Over the last decade, Graphics Processing Unit (GPU) architectures have evolved from a fixed-function graphics pipeline to a programmable, energy-efficient compute accelerator for massively parallel applications. The compute power arises from the GPU's Single Instruction/Multiple Threads

Using Cognitive Agents to Train Negotiation Skills

Directory of Open Access Journals (Sweden)

Christopher A. Stevens

2018-02-01

Full Text Available Training negotiation is difficult because it is a complex, dynamic activity that involves multiple parties. It is often not clear how to create situations in which students can practice negotiation or how to measure students' progress. Some have begun to address these issues by creating artificial software agents with which students can train. These agents have the advantage that they can be “reset,” and played against multiple times. This allows students to learn from their mistakes and try different strategies. However, these agents are often based on normative theories of how negotiators should conduct themselves, not necessarily how people actually behave in negotiations. Here, we take a step toward addressing this gap by developing an agent grounded in a cognitive architecture, ACT-R. This agent contains a model of theory-of-mind, the ability of humans to reason about the mental states of others. It uses this model to try to infer the strategy of the opponent and respond accordingly. In a series of experiments, we show that this agent replicates some aspects of human performance, is plausible to human negotiators, and can lead to learning gains in a small-scale negotiation task.

Using Cognitive Agents to Train Negotiation Skills.

Science.gov (United States)

Stevens, Christopher A; Daamen, Jeroen; Gaudrain, Emma; Renkema, Tom; Top, Jakob Dirk; Cnossen, Fokie; Taatgen, Niels A

2018-01-01

Training negotiation is difficult because it is a complex, dynamic activity that involves multiple parties. It is often not clear how to create situations in which students can practice negotiation or how to measure students' progress. Some have begun to address these issues by creating artificial software agents with which students can train. These agents have the advantage that they can be "reset," and played against multiple times. This allows students to learn from their mistakes and try different strategies. However, these agents are often based on normative theories of how negotiators should conduct themselves, not necessarily how people actually behave in negotiations. Here, we take a step toward addressing this gap by developing an agent grounded in a cognitive architecture, ACT-R. This agent contains a model of theory-of-mind, the ability of humans to reason about the mental states of others. It uses this model to try to infer the strategy of the opponent and respond accordingly. In a series of experiments, we show that this agent replicates some aspects of human performance, is plausible to human negotiators, and can lead to learning gains in a small-scale negotiation task.

Knowledge and Architectural Practice

DEFF Research Database (Denmark)

Verbeke, Johan

2017-01-01

of the level of research methods and will explain that the research methods and processes in creative practice research are very similar to grounded theory which is an established research method in the social sciences. Finally, an argument will be made for a more explicit research attitude in architectural......This paper focuses on the specific knowledge residing in architectural practice. It is based on the research of 35 PhD fellows in the ADAPT-r (Architecture, Design and Art Practice Training-research) project. The ADAPT-r project innovates architectural research in combining expertise from academia...... and from practice in order to highlight and extract the specific kind of knowledge which resides and is developed in architectural practice (creative practice research). The paper will discuss three ongoing and completed PhD projects and focusses on the outcomes and their contribution to the field...

Models in architectural design

OpenAIRE

Pauwels, Pieter

2017-01-01

Whereas architects and construction specialists used to rely mainly on sketches and physical models as representations of their own cognitive design models, they rely now more and more on computer models. Parametric models, generative models, as-built models, building information models (BIM), and so forth, they are used daily by any practitioner in architectural design and construction. Although processes of abstraction and the actual architectural model-based reasoning itself of course rema...

The cognitive roles of behavioral variability: idiosyncratic acts as the foundation of identity and as transitional, preparatory, and confirmatory phases.

Science.gov (United States)

Eilam, David

2015-02-01

Behavior in obsessive compulsive disorder (OCD), in habitual daily tasks, and in sport and cultural rituals is deconstructed into elemental acts and categorized into common acts, performed by all individuals completing a similar task, and idiosyncratic acts, not performed by all individuals. Never skipped, common acts establish the pragmatic part of motor tasks. Repetitive performance of a few common acts renders rituals a rigid form, whereby common acts may serve as memes for cultural transmission. While idiosyncratic acts are not pragmatically necessary for task completion, they fulfill important cognitive roles. They form a long preparatory phase in tasks that involve high stakes, and a long confirmatory phase in OCD rituals. Idiosyncratic acts also form transitional phases between motor tasks, and are involved in establishing identity and preserving the flexibility necessary for adapting to varying circumstances. Behavioral variability, as manifested in idiosyncrasy, thus does not seem to be a noise or by-product of motor activity, but an essential cognitive component that has been preserved in the evolution of behavioral patterns, similar to the genetic variability in biology. Copyright © 2014 Elsevier Ltd. All rights reserved.

Prototype development and demonstration for response, emergency staging, communications, uniform management, and evacuation (R.E.S.C.U.M.E.) : R.E.S.C.U.M.E. prototype system architecture.

Science.gov (United States)

2014-01-01

This document provides the high-level system architecture for the Prototype Development and Demonstration of a : R.E.S.C.U.M.E. system. The requirements addressed in this document are based upon those that can be found in : previous R.E.S.C.U.M.E. re...

Virtualized cognitive network architecture for 5G cellular networks

KAUST Repository

Elsawy, Hesham; Dahrouj, Hayssam; Al-Naffouri, Tareq Y.; Alouini, Mohamed-Slim

2015-01-01

, tactile Internet, online gaming, multimedia). Such an ossified architecture imposes several hurdles against achieving the ambitious metrics of next generation cellular systems. This article first highlights the features and drawbacks of such architectural

Fault Tolerant Control Architecture Design for Mobile Manipulation in Scientific Facilities

Directory of Open Access Journals (Sweden)

Mohammad M. Aref

2015-01-01

Full Text Available This paper describes one of the challenging issues implied by scientific infrastructures on a mobile robot cognition architecture. For a generally applicable cognition architecture, we study the dependencies and logical relations between several tasks and subsystems. The overall view of the software modules is described, including their relationship with a fault management module that monitors the consistency of the data flow among the modules. The fault management module is the solution of the deliberative architecture for the single point failures, and the safety anchor is the reactive solution for the faults by redundant equipment. In addition, a hardware architecture is proposed to ensure safe robot movement as a redundancy for the cognition of the robot. The method is designed for a four-wheel steerable (4WS mobile manipulator (iMoro as a case study.

1. The Acting Student’s Choreographic Training. Several Cognitive Objectives

Directory of Open Access Journals (Sweden)

Șușu Petre

2018-03-01

Full Text Available Dance is an artistic genre that is more and more frequently used in theatre productions. The syncretism of theatre and dance can take many shapes, from inserting dance sequences in dramatic performances, to new artistic genres, such as dance theatre. Due to the fact that they offer manifold innovating possibilities for artistic expression in a greatly audience-oriented universal language, theatrical forms that include dance, and especially the artistic genre of dance theatre are increasingly often put on stage by directors who work in Romania. Thus, training actors in the area of dance at a high level of performance that allows them to approach these types of syncretic artistic genres becomes a priority for the Romanian theatre school. The director, one of the stakeholders in higher education theatre schools, is the one who decides both the form of a performance and an actor’s involvement (or lack thereof in that certain performance. Limited or stimulated by the actor’s training level, the director is also a beneficiary of the education the acting student receives in drama school. This study aims at identifying the opinions of ten Romanian directors on the matter of the choreographic categories and skills the acting student acquires during his years of training at a higher education institution. We have used qualitative methodology research, based on semi-structured interviews, applied to a cross-section of ten directors from Bucharest, Cluj-Napoca, Constanţa, Craiova, Iaşi, and Tg. Mureş. This article tackles the issue of cognitive didactic objectives and students’ cognitive competencies that have been emphasized during the conversations with the aforementioned directors.

Representations and processes of human spatial competence.

Science.gov (United States)

Gunzelmann, Glenn; Lyon, Don R

2011-10-01

This article presents an approach to understanding human spatial competence that focuses on the representations and processes of spatial cognition and how they are integrated with cognition more generally. The foundational theoretical argument for this research is that spatial information processing is central to cognition more generally, in the sense that it is brought to bear ubiquitously to improve the adaptivity and effectiveness of perception, cognitive processing, and motor action. We describe research spanning multiple levels of complexity to understand both the detailed mechanisms of spatial cognition, and how they are utilized in complex, naturalistic tasks. In the process, we discuss the critical role of cognitive architectures in developing a consistent account that spans this breadth, and we note some areas in which the current version of a popular architecture, ACT-R, may need to be augmented. Finally, we suggest a framework for understanding the representations and processes of spatial competence and their role in human cognition generally. Copyright © 2011 Cognitive Science Society, Inc.

Lessons from cognitive neuropsychology for cognitive science: a reply to Patterson and Plaut (2009).

Science.gov (United States)

Coltheart, Max

2010-01-01

A recent article in this journal (Patterson & Plaut, 2009) argued that cognitive neuropsychology has told us very little over the past 30 or 40 years about "how the brain accomplishes its cognitive business." This may well be true, but it is not important, because the principal aim of cognitive neuropsychology is not to learn about the brain. Its principal aim is instead to learn about the mind, that is, to elucidate the functional architecture of cognition. I show that this is so (a) via extensive quotations from leading figures in this field and (b) by analysis of the subject matter of articles in the leading journal in the field, Cognitive Neuropsychology. Recent reviews of the past 25 years of work in this field (Coltheart & Caramazza, 2006) have concluded that cognitive neuropsychology has told us much about the functional architecture of cognition in a variety of cognitive domains. Patterson and Plaut (2009) did not consider this aim of cognitive neuropsychology. Therefore, their conclusions that cognitive neuropsychology has not been successful, and that this is because the particular methods it uses are flawed, are not justified. Copyright © 2009 Cognitive Science Society, Inc.

Bionics in architecture

Directory of Open Access Journals (Sweden)

Sugár Viktória

2017-04-01

Full Text Available The adaptation of the forms and phenomena of nature is not a recent concept. Observation of natural mechanisms has been a primary source of innovation since prehistoric ages, which can be perceived through the history of architecture. Currently, this idea is coming to the front again through sustainable architecture and adaptive design. Investigating natural innovations and the clear-outness of evolution during the 20th century led to the creation of a separate scientific discipline, Bionics. Architecture and Bionics are strongly related to each other, since the act of building is as old as the human civilization - moreover its first formal and structural source was obviously the surrounding environment. Present paper discusses the definition of Bionics and its connection with the architecture.

Embodying a cognitive model in a mobile robot

Science.gov (United States)

Benjamin, D. Paul; Lyons, Damian; Lonsdale, Deryle

2006-10-01

The ADAPT project is a collaboration of researchers in robotics, linguistics and artificial intelligence at three universities to create a cognitive architecture specifically designed to be embodied in a mobile robot. There are major respects in which existing cognitive architectures are inadequate for robot cognition. In particular, they lack support for true concurrency and for active perception. ADAPT addresses these deficiencies by modeling the world as a network of concurrent schemas, and modeling perception as problem solving. Schemas are represented using the RS (Robot Schemas) language, and are activated by spreading activation. RS provides a powerful language for distributed control of concurrent processes. Also, The formal semantics of RS provides the basis for the semantics of ADAPT's use of natural language. We have implemented the RS language in Soar, a mature cognitive architecture originally developed at CMU and used at a number of universities and companies. Soar's subgoaling and learning capabilities enable ADAPT to manage the complexity of its environment and to learn new schemas from experience. We describe the issues faced in developing an embodied cognitive architecture, and our implementation choices.

Effectively Managing the Air Force Enterprise Architecture

National Research Council Canada - National Science Library

Sharkey, Jamie P

2005-01-01

The Air Force is developing and implementing an enterprise architecture to meet the Clinger-Cohen Act's requirement that all federal agencies use an architecture to guide their information technology (IT) investments...

Toward Cognitively Constrained Models of Language Processing: A Review

Directory of Open Access Journals (Sweden)

Margreet Vogelzang

2017-09-01

Full Text Available Language processing is not an isolated capacity, but is embedded in other aspects of our cognition. However, it is still largely unexplored to what extent and how language processing interacts with general cognitive resources. This question can be investigated with cognitively constrained computational models, which simulate the cognitive processes involved in language processing. The theoretical claims implemented in cognitive models interact with general architectural constraints such as memory limitations. This way, it generates new predictions that can be tested in experiments, thus generating new data that can give rise to new theoretical insights. This theory-model-experiment cycle is a promising method for investigating aspects of language processing that are difficult to investigate with more traditional experimental techniques. This review specifically examines the language processing models of Lewis and Vasishth (2005, Reitter et al. (2011, and Van Rij et al. (2010, all implemented in the cognitive architecture Adaptive Control of Thought—Rational (Anderson et al., 2004. These models are all limited by the assumptions about cognitive capacities provided by the cognitive architecture, but use different linguistic approaches. Because of this, their comparison provides insight into the extent to which assumptions about general cognitive resources influence concretely implemented models of linguistic competence. For example, the sheer speed and accuracy of human language processing is a current challenge in the field of cognitive modeling, as it does not seem to adhere to the same memory and processing capacities that have been found in other cognitive processes. Architecture-based cognitive models of language processing may be able to make explicit which language-specific resources are needed to acquire and process natural language. The review sheds light on cognitively constrained models of language processing from two angles: we

Circulating exosomal miR-27a and miR-130a act as novel diagnostic and prognostic biomarkers of colorectal cancer.

Science.gov (United States)

Wang, Shukui; Liu, Xiangxiang; Pan, Bei; Sun, Li; Chen, Xiaoxiang; Zeng, Kaixuan; Hu, Xiuxiu; Xu, Tao; Xu, Mu

2018-05-08

Colorectal cancer (CRC) is one of the most common cancers worldwide usually with poor prognosis due to the advanced stage when diagnosed. This study aimed to investigate whether specific circulating exosomal miRNAs could act as biomarkers for early diagnosis of CRC. A total of 369 peripheral blood samples were included in this study. In the discovery phase, circulating exosomal miR-27a and miR-130a were selected after synthetical analysis of two GEO datasets and TCGA database. The differential expression and diagnostic utility of miR-27a and miR-130a panel were validated using quantitative reverse-transcriptase PCR (qRT-PCR) and Receiver operating characteristic (ROC) curve analysis in subsequent training phase, validation phase and external validation phase. The prognosis of circulating exosomal miR-27a and miR-130a were investigated using the Kaplan-Meier method. The expression of exosomal miR-27a and miR-130a in plasma significantly increased in CRC. The area under ROC curves (AUCs) of miR-27a (miR-130a) were 0.773 (0.742) in the training phase, 0.82 (0.787) in the validation phase, and 0.746 (0.697) in the external validation phase. The combination of two miRNAs presented higher diagnostic utility for CRC (AUCs = 0.846, 0.898 and 0.801 for the training, validation, and external validation phases, respectively). CRC patients with high expression of circulating exosomal miR-27a or miR-130a underwent poorer prognosis. We identified a circulating exosomal miRNAs panel for the detection of CRC. The exosomal miR-27a and miR-130a panel in plasma may act as a non-invasive biomarker for early detection and predicting prognosis of CRC. Copyright ©2018, American Association for Cancer Research.

Dedicated clock/timing-circuit theories of time perception and timed performance.

Science.gov (United States)

van Rijn, Hedderik; Gu, Bon-Mi; Meck, Warren H

2014-01-01

Scalar Timing Theory (an information-processing version of Scalar Expectancy Theory) and its evolution into the neurobiologically plausible Striatal Beat-Frequency (SBF) theory of interval timing are reviewed. These pacemaker/accumulator or oscillation/coincidence detection models are then integrated with the Adaptive Control of Thought-Rational (ACT-R) cognitive architecture as dedicated timing modules that are able to make use of the memory and decision-making mechanisms contained in ACT-R. The different predictions made by the incorporation of these timing modules into ACT-R are discussed as well as the potential limitations. Novel implementations of the original SBF model that allow it to be incorporated into ACT-R in a more fundamental fashion than the earlier simulations of Scalar Timing Theory are also considered in conjunction with the proposed properties and neural correlates of the "internal clock".

Space Telecommunications Radio System STRS Cognitive Radio

Science.gov (United States)

Briones, Janette C.; Handler, Louis M.

2013-01-01

Radios today are evolving from awareness toward cognition. A software defined radio (SDR) provides the most capability for integrating autonomic decision making ability and allows the incremental evolution toward a cognitive radio. This cognitive radio technology will impact NASA space communications in areas such as spectrum utilization, interoperability, network operations, and radio resource management over a wide range of operating conditions. NASAs cognitive radio will build upon the infrastructure being developed by Space Telecommunication Radio System (STRS) SDR technology. This paper explores the feasibility of inserting cognitive capabilities in the NASA STRS architecture and the interfaces between the cognitive engine and the STRS radio. The STRS architecture defines methods that can inform the cognitive engine about the radio environment so that the cognitive engine can learn autonomously from experience, and take appropriate actions to adapt the radio operating characteristics and optimize performance.

Relationship between cognitive and non-cognitive symptoms of delirium.

Science.gov (United States)

Rajlakshmi, Aarya Krishnan; Mattoo, Surendra Kumar; Grover, Sandeep

2013-04-01

To study relationship between the cognitive and the non-cognitive symptoms of delirium. Eighty-four patients referred to psychiatry liaison services and met DSM-IVTR criteria of delirium were assessed using the Delirium Rating Scale Revised-1998 (DRSR-98) and Cognitive Test for Delirium (CTD). The mean DRS-R-98 severity score was 17.19 and DRS-R-98 total score was 23.36. The mean total score on CTD was 11.75. The mean scores on CTD were highest for comprehension (3.47) and lowest for vigilance (1.71). Poor attention was associated with significantly higher motor retardation and higher DRS-R-98 severity scores minus the attention scores. There were no significant differences between those with and without poor attention. Higher attention deficits were associated with higher dysfunction on all other domains of cognition on CTD. There was significant correlation between cognitive functions as assessed on CTD and total DRS-R-98 score, DRS-R-98 severity score and DRS-R-98 severity score without the attention item score. However, few correlations emerged between CTD domains and CTD total scores with cognitive symptom total score of DRS-R-98 (items 9-13) and non-cognitive symptom total score of DRS-R-98 (items 1-8). Our study suggests that in delirium, cognitive deficits are quite prevalent and correlate with overall severity of delirium. Attention deficit is a core symptom of delirium. Copyright © 2012 Elsevier B.V. All rights reserved.

Considerations for the Next Revision of NASA's Space Telecommunications Radio System Architecture

Science.gov (United States)

Johnson, Sandra K.; Handler, Louis M.; Briones, Janette C.

2016-01-01

Development of NASA's Software Defined Radio architecture, the Space Telecommunication Radio System (STRS), was initiated in 2004 with a goal of reducing the cost, risk and schedule when implementing Software Defined Radios (SDR) for National Aeronautics and Space Administration (NASA) space missions. Since STRS was first flown in 2012 on three Software Defined Radios on the Space Communication and Navigation (SCaN) Testbed, only minor changes have been made to the architecture. Multiple entities have since implemented the architecture and provided significant feedback for consideration for the next revision of the standard. The focus for the first set of updates to the architecture is items that enhance application portability. Items that require modifications to existing applications before migrating to the updated architecture will only be considered if there is compelling reasons to make the change. The significant suggestions that were further evaluated for consideration include expanding and clarifying the timing Application Programming Interfaces (APIs), improving handle name and identification (ID) definitions and use, and multiple items related to implementation of STRS Devices. In addition to ideas suggested while implementing STRS, SDR technology has evolved significantly and this impact to the architecture needs to be considered. These include incorporating cognitive concepts - learning from past decisions and making new decisions that the radio can act upon. SDRs are also being developed that do not contain a General Purpose Module - which is currently required for the platform to be STRS compliant. The purpose of this paper is to discuss the comments received, provide a summary of the evaluation considerations, and examine planned dispositions.

The architecture of the BubR1 tetratricopeptide tandem repeat defines a protein motif underlying mitotic checkpoint-kinetochore communication

DEFF Research Database (Denmark)

Bolanos-Garcia, Victor M; Nilsson, Jakob; Blundell, Tom L

2012-01-01

advance to anaphase before every chromosome is properly attached to microtubules of the mitotic spindle. The architecture of the KNL1-BubR1 complex reveals important features of the molecular recognition between SAC components and the kinetochore. The interaction is important for a functional SAC...... as substitution of BubR1 residues engaged in KNL1 binding impaired the SAC and BubR1 recruitment into checkpoint complexes in stable cell lines. Here we discuss the implications of the disorder-to-order transition of KNL1 upon BubR1 binding for SAC signaling and propose a mechanistic model of how BUBs binding may...

Cognitive load theory: implications of cognitive load theory on the design of learning

NARCIS (Netherlands)

Kirschner, P.A.

2002-01-01

Cognitive load theory (CLT) can provide guidelines to assist in the presentation of information in a manner that encourages learner activities that optimise intellectual performance. It is based on a cognitive architecture that consists of a limited working memory, with partly independent

Towards a networkArchitecture

DEFF Research Database (Denmark)

Rüdiger, Bjarne; Tournay, Bruno

2001-01-01

Planche, bidrag til DAL-konkurrencen. Hvor industrien har været inspirationen for udviklingen af den moderne arkitektur, er IT det tekniske og æstetiske grundlag for den spirende NetworkArchitecture. Computeren og netværker af computerne er således mere end en metafor for NetworkArchitecture....... NetworkArchitecture består af intelligente byggekomponenter forbundet med hinanden i et netværk og i interaktion med omgivelser....

Carnegie Learning Curricula and Cognitive Tutor[R] Software. What Works Clearinghouse Intervention Report

Science.gov (United States)

What Works Clearinghouse, 2010

2010-01-01

The combination of "Carnegie Learning Curricula and Cognitive Tutor[R] Software" merges algebra textbooks with interactive software developed around an artificial intelligence model that identifies strengths and weaknesses in an individual student's mastery of mathematical concepts. The software customizes prompts to focus on areas in…

Thioredoxin is not a marker for treatment-resistance depression but associated with cognitive function: An rTMS study.

Science.gov (United States)

Aydın, Efruz Pirdoğan; Genç, Abdullah; Dalkıran, Mihriban; Uyar, Ece Türkyilmaz; Deniz, İpek; Özer, Ömer Akil; Karamustafalıoğlu, Kayıhan Oğuz

2018-01-03

Elevated oxidative stress is known to play an important role in development of depression and cognitive dysfunction. To date, thioredoxin (TRX), an antioxidant protein, has been investigated as a marker for psychiatric disorders such as schizophrenia, bipolar disorder and autism but its relationship with depression is yet to be unknown. The aim of this study is to detect the TRX levels in patients with treatment-resistant depression (TRD), analyse the effect of rTMS (repetitive transcranial magnetic stimulation) application on TRX levels and display the relationship of TRX with cognitive areas. This study included 27 treatment-resistant unipolar depression patients and 29 healthy subjects. Patients were evaluated by Hamilton Depression Scale (HDRS), Hamilton Anxiety Scale (HARS) and Montreal Cognitive Assessment (MoCA) before and after rTMS application. 23 of TRD patients were applied high-frequency rTMS over left DLPFC for 2 to 4weeks and plasma TRX levels of patients and healthy subjects were measured. No significant difference was determined between the TRX levels of patients and healthy subjects (p>0.05). After rTMS application there were significant decrease in severity of depression (pTRX levels of the patients after rTMS application (p>0.005). High language scores of the patients were found to be associated with high TRX levels (pTRX levels cannot be used as a marker for TRD or rTMS treatment in TRD. In spite of this TRX levels have a positive correlation with language functions of the patients of TRD. More extensive studies are required to clarify the mechanism of action of TRX and the effect of TRX on cognitive functions. Copyright © 2017 Elsevier Inc. All rights reserved.

Study on the utilization of the cognitive architecture EPIC to the task analysis of a nuclear power plant operator

International Nuclear Information System (INIS)

Soares, Herculano Vieira

2003-02-01

This work presents a study of the use of the integrative cognitive architecture EPIC - Executive-Process - Interactive-Control, designed to evaluate the performance of a person performing tasks in parallel in a man-machine interface, as a methodology for Cognitive Task Analysis of a nuclear power plant operator. A comparison of the results obtained by the simulation by EPIC and the results obtained by application of the MHP model to the tasks performed by a shift operator during the execution of the procedure PO-E-3 - Steam Generator Tube Rupture of Angra 1 Nuclear Power Plant is done. To subsidize that comparison, an experiment was performed at the Angra 2 Nuclear Power Plant Full Scope Simulator in which three operator tasks were executed, its completion time measured and compared with the results of MHP and EPIC modeling. (author)

Digitally-Driven Architecture

Directory of Open Access Journals (Sweden)

Henriette Bier

2014-07-01

Full Text Available The shift from mechanical to digital forces architects to reposition themselves: Architects generate digital information, which can be used not only in designing and fabricating building components but also in embedding behaviours into buildings. This implies that, similar to the way that industrial design and fabrication with its concepts of standardisation and serial production influenced modernist architecture, digital design and fabrication influences contemporary architecture. While standardisation focused on processes of rationalisation of form, mass-customisation as a new paradigm that replaces mass-production, addresses non-standard, complex, and flexible designs. Furthermore, knowledge about the designed object can be encoded in digital data pertaining not just to the geometry of a design but also to its physical or other behaviours within an environment. Digitally-driven architecture implies, therefore, not only digitally-designed and fabricated architecture, it also implies architecture – built form – that can be controlled, actuated, and animated by digital means.In this context, this sixth Footprint issue examines the influence of digital means as pragmatic and conceptual instruments for actuating architecture. The focus is not so much on computer-based systems for the development of architectural designs, but on architecture incorporating digital control, sens­ing, actuating, or other mechanisms that enable buildings to inter­act with their users and surroundings in real time in the real world through physical or sensory change and variation.

Concurrent Validity of the Woodcock-Johnson Tests of Cognitive Ability with the WISC-R: EMR Children.

Science.gov (United States)

Cummings, Jack A.; Sanville, David

1983-01-01

Administered the Wechsler Intelligence Scale for Children-Revised (WISC-R) and the Woodcock-Johnson Tests of Cognitive Ability (WJTCA) to educable mentally retarded children (N=30). Results showed significant mean differences between WISC-R and WJTCA full-scale standard scores, providing implications for placement of children in classes for the…

Psychometric properties of the Greek TCI-R and its clinical correlates: schizotypy and the self-regulation of affective and cognitive functioning.

Science.gov (United States)

Giakoumaki, Stella G; Karagiannopoulou, Leda; Rózsa, Sándor; Zouraraki, Chrysoula; Karamaouna, Penny; Cloninger, C Robert

2016-01-01

Background. The revised Temperament and Character Inventory (TCI-R) measures Cloninger's psychobiological model of personality. The average effects of individual temperament and character traits have been associated with schizotypy and with impaired regulation of affect and cognition. We extended prior research by testing predictions about the association of specific multidimensional configurations of temperament and character traits on schizotypy, affect balance, and self-perceived cognitive functioning. Method. A well-educated sample of native Greeks (N = 483), completed a new Greek translation of the TCI-R, as well as the Schizotypal Personality Questionnaire (SPQ), the Positive/Negative Affect Schedule (PANAS) and the Cognitive Failures Questionnaire (CFQ). The factor structure of the TCI-R was examined with exploratory and confirmatory tests. Associations between reported measures were examined with correlational and regression analyses. Results. The TCI-R had good psychometric properties as expected from studies in other countries. As predicted, specific configurations of temperament and character were associated with schizotypy, negative affect balance, and cognitive lapses. The "Borderline/Explosive temperament" (high Novelty Seeking, high Harm Avoidance, low Reward Dependence), "Schizotypal/Disorganized character" (low Self-directedness, low Cooperativeness, high Self-transcendence), and "Low Ego Strength/Fragile" profile (high Harm Avoidance, low Persistence, low Self-Directedness) were each strongly associated with higher stereotypy, negative affect balance (low positive affect and high negative affect), and subjective cognitive lapses compared to their contrast groups. Discussion. Multidimensional TCI profiles are strongly related to individual differences in schizotypy and self-reported regulation of affect and cognition. The Greek translation of the TCI-R is psychometrically sound and useful for clinical assessment and research.

Creative Practices Embodied, Embedded, and Enacted in Architectural Settings: Toward an Ecological Model of Creativity

Science.gov (United States)

Malinin, Laura H.

2016-01-01

Memoires by eminently creative people often describe architectural spaces and qualities they believe instrumental for their creativity. However, places designed to encourage creativity have had mixed results, with some found to decrease creative productivity for users. This may be due, in part, to lack of suitable empirical theory or model to guide design strategies. Relationships between creative cognition and features of the physical environment remain largely uninvestigated in the scientific literature, despite general agreement among researchers that human cognition is physically and socially situated. This paper investigates what role architectural settings may play in creative processes by examining documented first person and biographical accounts of creativity with respect to three central theories of situated cognition. First, the embodied thesis argues that cognition encompasses both the mind and the body. Second, the embedded thesis maintains that people exploit features of the physical and social environment to increase their cognitive capabilities. Third, the enaction thesis describes cognition as dependent upon a person’s interactions with the world. Common themes inform three propositions, illustrated in a new theoretical framework describing relationships between people and their architectural settings with respect to different cognitive processes of creativity. The framework is intended as a starting point toward an ecological model of creativity, which may be used to guide future creative process research and architectural design strategies to support user creative productivity. PMID:26779087

Creative Practices Embodied, Embedded, and Enacted in Architectural Settings: Toward an Ecological Model of Creativity.

Science.gov (United States)

Malinin, Laura H

2015-01-01

Memoires by eminently creative people often describe architectural spaces and qualities they believe instrumental for their creativity. However, places designed to encourage creativity have had mixed results, with some found to decrease creative productivity for users. This may be due, in part, to lack of suitable empirical theory or model to guide design strategies. Relationships between creative cognition and features of the physical environment remain largely uninvestigated in the scientific literature, despite general agreement among researchers that human cognition is physically and socially situated. This paper investigates what role architectural settings may play in creative processes by examining documented first person and biographical accounts of creativity with respect to three central theories of situated cognition. First, the embodied thesis argues that cognition encompasses both the mind and the body. Second, the embedded thesis maintains that people exploit features of the physical and social environment to increase their cognitive capabilities. Third, the enaction thesis describes cognition as dependent upon a person's interactions with the world. Common themes inform three propositions, illustrated in a new theoretical framework describing relationships between people and their architectural settings with respect to different cognitive processes of creativity. The framework is intended as a starting point toward an ecological model of creativity, which may be used to guide future creative process research and architectural design strategies to support user creative productivity.

TetR-dependent gene regulation in intracellular Listeria monocytogenes demonstrates the spatiotemporal surface distribution of ActA.

Science.gov (United States)

Schmitter, Sibylle; Fieseler, Lars; Klumpp, Jochen; Bertram, Ralph; Loessner, Martin J

2017-08-01

To enable specific and tightly controlled gene expression both in vitro and during the intracellular lifecycle of the pathogen Listeria monocytogenes, a TetR-dependent genetic induction system was developed. Highest concentration of cytoplasmic TetR and best repression of tetO-controlled genes was obtained by tetR expression from the synthetic promoter Pt 17 . Anhydrotetracycline (ATc) as inducer permitted concentration-dependent, fine-tuned expression of genes under control of the tetO operator and a suitable promoter. The actin-polymerizing ActA protein represents a major virulence factor of L. monocytogenes, required for actin-based motility and cell-to-cell spread in infected host cells. To be able to observe its spatial and temporal distribution on intracellular L. monocytogenes cells, conditional mutants featuring actA placed under TetR control were used to infect PtK2 epithelial cells. Following induction at different time intervals, the subsequent recruitment of actin by L. monocytogenes could be monitored. We found that cells displayed functional ActA after approximately 15 min, while formation of polarized actin tail was complete after 90-120 min. At this point, intracellular motility of the induced mutants was indistinguishable from wild-type bacteria. Interestingly, de novo ActA synthesis in intracellular Listeria also demonstrated the temporal, asymmetric redistribution of the membrane-anchored proteins from the lateral walls toward the cell poles. © 2017 John Wiley & Sons Ltd.

The Design of a Polymorphous Cognitive Agent Architecture (PCAA)

Science.gov (United States)

2008-05-01

this scenario is very similar to the classic Traveling Salesman Problem (TSP). However, this problem has a strong cognitive aspect , and the goal was to...strong cognitive aspect , and the goal was to focus on this aspect rather than to find a possibly quicker non-cognitive solution. Additionally

N-Doped Dual Carbon-Confined 3D Architecture rGO/Fe3O4/AC Nanocomposite for High-Performance Lithium-Ion Batteries.

Science.gov (United States)

Ding, Ranran; Zhang, Jie; Qi, Jie; Li, Zhenhua; Wang, Chengyang; Chen, Mingming

2018-04-25

To address the issues of low electrical conductivity, sluggish lithiation kinetics and dramatic volume variation in Fe 3 O 4 anodes of lithium ion battery, herein, a double carbon-confined three-dimensional (3D) nanocomposite architecture was synthesized by an electrostatically assisted self-assembly strategy. In the constructed architecture, the ultrafine Fe 3 O 4 subunits (∼10 nm) self-organize to form nanospheres (NSs) that are fully coated by amorphous carbon (AC), formatting core-shell structural Fe 3 O 4 /AC NSs. By further encapsulation by reduced graphene oxide (rGO) layers, a constructed 3D architecture was built as dual carbon-confined rGO/Fe 3 O 4 /AC. Such structure restrains the adverse reaction of the electrolyte, improves the electronic conductivity and buffers the mechanical stress of the entire electrode, thus performing excellent long-term cycling stability (99.4% capacity retention after 465 cycles relevant to the second cycle at 5 A g -1 ). Kinetic analysis reveals that a dual lithium storage mechanism including a diffusion reaction mechanism and a surface capacitive behavior mechanism coexists in the composites. Consequently, the resulting rGO/Fe 3 O 4 /AC nanocomposite delivers a high reversible capacity (835.8 mA h g -1 for 300 cycles at 1 A g -1 ), as well as remarkable rate capability (436.7 mA h g -1 at 10 A g -1 ).

Mechanisms for Human Spatial Competence

Science.gov (United States)

Gunzelmann, Glenn; Lyon, Don R.

Research spanning decades has generated a long list of phenomena associated with human spatial information processing. Additionally, a number of theories have been proposed about the representation, organization and processing of spatial information by humans. This paper presents a broad account of human spatial competence, integrated with the ACT-R cognitive architecture. Using a cognitive architecture grounds the research in a validated theory of human cognition, enhancing the plausibility of the overall account. This work posits a close link of aspects of spatial information processing to vision and motor planning, and integrates theoretical perspectives that have been proposed over the history of research in this area. In addition, the account is supported by evidence from neuropsychological investigations of human spatial ability. The mechanisms provide a means of accounting for a broad range of phenomena described in the experimental literature.

Psychometric properties of the Greek TCI-R and its clinical correlates: schizotypy and the self-regulation of affective and cognitive functioning

Directory of Open Access Journals (Sweden)

Stella G. Giakoumaki

2016-03-01

Full Text Available Background. The revised Temperament and Character Inventory (TCI-R measures Cloninger’s psychobiological model of personality. The average effects of individual temperament and character traits have been associated with schizotypy and with impaired regulation of affect and cognition. We extended prior research by testing predictions about the association of specific multidimensional configurations of temperament and character traits on schizotypy, affect balance, and self-perceived cognitive functioning. Method. A well-educated sample of native Greeks (N = 483, completed a new Greek translation of the TCI-R, as well as the Schizotypal Personality Questionnaire (SPQ, the Positive/Negative Affect Schedule (PANAS and the Cognitive Failures Questionnaire (CFQ. The factor structure of the TCI-R was examined with exploratory and confirmatory tests. Associations between reported measures were examined with correlational and regression analyses. Results. The TCI-R had good psychometric properties as expected from studies in other countries. As predicted, specific configurations of temperament and character were associated with schizotypy, negative affect balance, and cognitive lapses. The “Borderline/Explosive temperament” (high Novelty Seeking, high Harm Avoidance, low Reward Dependence, “Schizotypal/Disorganized character” (low Self-directedness, low Cooperativeness, high Self-transcendence, and “Low Ego Strength/Fragile” profile (high Harm Avoidance, low Persistence, low Self-Directedness were each strongly associated with higher stereotypy, negative affect balance (low positive affect and high negative affect, and subjective cognitive lapses compared to their contrast groups. Discussion. Multidimensional TCI profiles are strongly related to individual differences in schizotypy and self-reported regulation of affect and cognition. The Greek translation of the TCI-R is psychometrically sound and useful for clinical assessment and

Digitally-Driven Architecture

Directory of Open Access Journals (Sweden)

Henriette Bier

2010-06-01

Full Text Available The shift from mechanical to digital forces architects to reposition themselves: Architects generate digital information, which can be used not only in designing and fabricating building components but also in embedding behaviours into buildings. This implies that, similar to the way that industrial design and fabrication with its concepts of standardisation and serial production influenced modernist architecture, digital design and fabrication influences contemporary architecture. While standardisa­tion focused on processes of rationalisation of form, mass-customisation as a new paradigm that replaces mass-production, addresses non-standard, complex, and flexible designs. Furthermore, knowledge about the designed object can be encoded in digital data pertaining not just to the geometry of a design but also to its physical or other behaviours within an environment. Digitally-driven architecture implies, therefore, not only digitally-designed and fabricated architecture, it also implies architecture – built form – that can be controlled, actuated, and animated by digital means. In this context, this sixth Footprint issue examines the influence of digital means as prag­matic and conceptual instruments for actuating architecture. The focus is not so much on computer-based systems for the development of architectural designs, but on architecture incorporating digital control, sens­ing, actuating, or other mechanisms that enable buildings to inter­act with their users and surroundings in real time in the real world through physical or sensory change and variation.

Multimedia over cognitive radio networks algorithms, protocols, and experiments

CERN Document Server

Hu, Fei

2014-01-01

PrefaceAbout the EditorsContributorsNetwork Architecture to Support Multimedia over CRNA Management Architecture for Multimedia Communication in Cognitive Radio NetworksAlexandru O. Popescu, Yong Yao, Markus Fiedler , and Adrian P. PopescuPaving a Wider Way for Multimedia over Cognitive Radios: An Overview of Wideband Spectrum Sensing AlgorithmsBashar I. Ahmad, Hongjian Sun, Cong Ling, and Arumugam NallanathanBargaining-Based Spectrum Sharing for Broadband Multimedia Services in Cognitive Radio NetworkYang Yan, Xiang Chen, Xiaofeng Zhong, Ming Zhao, and Jing WangPhysical Layer Mobility Challen

Global efficiency of structural networks mediates cognitive control in Mild Cognitive Impairment

Directory of Open Access Journals (Sweden)

Rok Berlot

2016-12-01

Full Text Available Background: Cognitive control has been linked to both the microstructure of individual tracts and the structure of whole-brain networks, but their relative contributions in health and disease remain unclear. Objective: To determine the contribution of both localised white matter tract damage and disruption of global network architecture to cognitive control, in older age and Mild Cognitive Impairment (MCI.Methods: 25 patients with MCI and 20 age, sex and intelligence-matched healthy volunteers were investigated with 3 Tesla structural magnetic resonance imaging (MRI. Cognitive control and episodic memory were evaluated with established tests. Structural network graphs were constructed from diffusion MRI-based whole-brain tractography. Their global measures were calculated using graph theory. Regression models utilized both global network metrics and microstructure of specific connections, known to be critical for each domain, to predict cognitive scores. Results: Global efficiency and the mean clustering coefficient of networks were reduced in MCI. Cognitive control was associated with global network topology. Episodic memory, in contrast, correlated with individual temporal tracts only. Relationships between cognitive control and network topology were attenuated by addition of single tract measures to regression models, consistent with a partial mediation effect. The mediation effect was stronger in MCI than healthy volunteers, explaining 23-36% of the effect of cingulum microstructure on cognitive control performance. Network clustering was a significant mediator in the relationship between tract microstructure and cognitive control in both groups. Conclusions: The status of critical connections and large-scale network topology are both important for maintenance of cognitive control in MCI. Mediation via large-scale networks is more important in patients with MCI than healthy volunteers. This effect is domain-specific, and true for cognitive

An account of cognitive flexibility and inflexibility for a complex dynamic task

OpenAIRE

De Obeso Orendain, Alberto; Wood, Sharon

2012-01-01

Problem solving involves adapting known problem solving methods and strategies to the task at hand (Schunn & Reder, 2001) and cognitive flexibility is considered to be “the human ability to adapt the cognitive processing strategies to face new and unexpected conditions of the environment” (Cañas et al., 2005, p. 95). This work presents an ACT-R 6.0 model of complex problem solving behavior for the dynamic microworld game FireChief (Omodei & Wearing, 1995) that models the performance of partic...

A Surgery Issue: Cutting through the Architectural Fabric

Directory of Open Access Journals (Sweden)

Athina Angelopoulou

2017-12-01

Full Text Available This essay examines the material ontologies of surgical trans-modifications. Focusing on incisions and subsequent scars, the essay argues for the queering of architecture and design as an act of cutting through structures and processes. I start by rereading a topological body plan, used by surgeons as a guide for performing incisions. I suggest that this plan constitutes a variation within topological representations. It is thus reconceptualised as an internally contradictory representation, calling for dis/continuous cutting acts upon the represented body; that is an amphi-topological representation. The notion of the cut is further approached from the point of view of queer theory and ‘agential realism’. This perspective offers affirmative ways of discussing about acts of cutting. When performed into self-organizing fabrics, cuts appear to act as ‘agents of dis/continuity’. Then, the discussion passes through the genealogy of the architectural section and the building cuts of Gordon Matta Clark, so as to show that the production of buildings by ‘cutting through them to come to matter’ is deep-rooted in the architectural discipline. Next, the philosophical origins of the idea of cutting through the material fabric of the world are sought. It is argued that the latter, beginning as a gnosiological tool, was transformed into a fabricating tool and then into a tool of smoothing the striated. The essay concludes with the presentation of SCARchiCAD; a computational design tool which takes the skin’s wound healing process as a model, offering an interpretation of what the ‘cutting through a virtual form’ could suggest for the design of architectural bodies and the queering of architecture.

78 FR 67303 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Buildings and Facilities...

Science.gov (United States)

2013-11-12

... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD 36 CFR Part 1191 RIN 3014-AA22 Americans With Disabilities Act (ADA) Accessibility Guidelines for Buildings and Facilities; Architectural Barriers Act (ABA) Accessibility Guidelines; Correction AGENCY: Architectural and Transportation Barriers...

Openness and ‘closedness’ in Roman tomb architecture

DEFF Research Database (Denmark)

Petersen, Jane Hjarl

2014-01-01

This paper examines the early columbaria of the Laurentina necropolis in Ostia, in particular Tomb E1, in light of modern architectural theories concerning human responses to and use of architectural patterns, specifically the idea that patterns act as strong catalysts in generating a sense...

[Preventing violence in schizophrenia with cognitive remediation].

Science.gov (United States)

Darmedru, C; Demily, C; Franck, N

2018-04-01

of the violent and aggressive behaviors of these patients. Various cognitive remediation programs have shown their feasibility in people with schizophrenia and neurocognitive deficits with a history of violence as well as their effectiveness in reducing violence, mainly by reducing impulsivity. Similarly, specific programs dedicated to social cognitive training such as Social Cognition and Interaction Training (SCIT), Reasoning and Rehabilitation Mental Health Program (R&R2 MHP) and Metacognitive Training (MCT) have shown their positive impact on the control and reduction of global aggressive attitudes and on the numbers of physical and verbal aggressive incidents in schizophrenia. The improvement of social cognition would be achieved through the amendment of interpersonal relationships and social functioning. These interventions are effective at different stages of disease progression, in patients with varied profiles, on violent attitudes in general and on the number of verbal and physical attacks, whether for in-patients or out-patients. Beneficial effects can last up to 12months after termination of the study program. The interest of these interventions is preventive if the subject never entered in a violent register or curative in case of a personal history of violence. This type of care can be considered from a symptomatic point of view by limiting downstream the heavy consequences of such acts, but also etiologically by acting on one of the causes of violent behavior. Compliance with the eligibility criteria, carrying out a prior functional analysis and confirmation of the major impulsive part of the patient's violence are prerequisites for the use of these programs. Similarly, the early introduction of such therapies, their repetition over time and the integration of the patient into a comprehensive process of psychosocial rehabilitation will ensure the best chance of success. Some cognitive impairments appear to have their place in the genesis, progression

Toward a Formal Model of Cognitive Synergy

OpenAIRE

Goertzel, Ben

2017-01-01

"Cognitive synergy" refers to a dynamic in which multiple cognitive processes, cooperating to control the same cognitive system, assist each other in overcoming bottlenecks encountered during their internal processing. Cognitive synergy has been posited as a key feature of real-world general intelligence, and has been used explicitly in the design of the OpenCog cognitive architecture. Here category theory and related concepts are used to give a formalization of the cognitive synergy concept....

Performative Urban Architecture

DEFF Research Database (Denmark)

Thomsen, Bo Stjerne; Jensen, Ole B.

The paper explores how performative urban architecture can enhance community-making and public domain using socio-technical systems and digital technologies to constitute an urban reality. Digital medias developed for the web are now increasingly occupying the urban realm as a tool for navigating...... the physical world e.g. as exemplified by the Google Walk Score and the mobile extension of the Google Maps to the iPhone. At the same time the development in pervasive technologies and situated computing extends the build environment with digital feedback systems that are increasingly embedded and deployed...... using sensor technologies opening up for new access considerations in architecture as well as the ability for a local environment to act as real-time sources of information and facilities. Starting from the NoRA pavilion for the 10th International Architecture Biennale in Venice the paper discusses...

The regional localization of a new potent centrally acting antihypertensive agent R 28935 and its less active threo isomer R 29814 in the cat brain

NARCIS (Netherlands)

Loonen, A.J.M.; Soudijn, W.; Van Rooy, H.H.; Van Wijngaarden, I.

1977-01-01

Systemic administration of the centrally acting antihypertensive agent R 28935 to cats resulted in a long lasting decrease of mean arterial pressure (±30%) whereas the same dose of the threo-isomer R 29814 was ineffective. The antihypertensive activity was due to the unaltered drug. In spite of an

Randomized Clinical Trial of Cognitive Behavioral Therapy (CBT) versus Acceptance and Commitment Therapy (ACT) for Mixed Anxiety Disorders

Science.gov (United States)

Arch, Joanna J.; Eifert, Georg H.; Davies, Carolyn; Vilardaga, Jennifer C. Plumb; Rose, Raphael D.; Craske, Michelle G.

2012-01-01

Objective: Randomized comparisons of acceptance-based treatments with traditional cognitive behavioral therapy (CBT) for anxiety disorders are lacking. To address this gap, we compared acceptance and commitment therapy (ACT) to CBT for heterogeneous anxiety disorders. Method: One hundred twenty-eight individuals (52% female, mean age = 38, 33%…

The genetic basis for cognitive ability, memory, and depression symptomatology in middle-aged and elderly chinese twins.

Science.gov (United States)

Xu, Chunsheng; Sun, Jianping; Ji, Fuling; Tian, Xiaocao; Duan, Haiping; Zhai, Yaoming; Wang, Shaojie; Pang, Zengchang; Zhang, Dongfeng; Zhao, Zhongtang; Li, Shuxia; Hjelmborg, Jacob V B; Christensen, Kaare; Tan, Qihua

2015-02-01

The genetic influences on aging-related phenotypes, including cognition and depression, have been well confirmed in the Western populations. We performed the first twin-based analysis on cognitive performance, memory and depression status in middle-aged and elderly Chinese twins, representing the world's largest and most rapidly aging population. The sample consisted of 384 twin pairs with a median age of 50 years. Cognitive function was measured using the Montreal Cognitive Assessment (MoCA) scale; memory was assessed using the revised Wechsler Adult Intelligence scale; depression symptomatology was evaluated by the self-reported 30-item Geriatric Depression (GDS-30)scale. Both univariate and multivariate twin models were fitted to the three phenotypes with full and nested models and compared to select the best fitting models. Univariate analysis showed moderate-to-high genetic influences with heritability 0.44 for cognition and 0.56 for memory. Multivariate analysis by the reduced Cholesky model estimated significant genetic (rG = 0.69) and unique environmental (rE = 0.25) correlation between cognitive ability and memory. The model also estimated weak but significant inverse genetic correlation for depression with cognition (-0.31) and memory (-0.28). No significant unique environmental correlation was found for depression with other two phenotypes. In conclusion, there can be a common genetic architecture for cognitive ability and memory that weakly correlates with depression symptomatology, but in the opposite direction.

An Evolutionary Upgrade of Cognitive Load Theory: Using the Human Motor System and Collaboration to Support the Learning of Complex Cognitive Tasks

NARCIS (Netherlands)

G.W.C. Paas (Fred); J. Sweller (John)

2012-01-01

textabstractCognitive load theory is intended to provide instructional strategies derived from experimental, cognitive load effects. Each effect is based on our knowledge of human cognitive architecture, primarily the limited capacity and duration of a human working memory. These limitations are

Predicting Long-Term College Success through Degree Completion Using ACT[R] Composite Score, ACT Benchmarks, and High School Grade Point Average. ACT Research Report Series, 2012 (5)

Science.gov (United States)

Radunzel, Justine; Noble, Julie

2012-01-01

This study compared the effectiveness of ACT[R] Composite score and high school grade point average (HSGPA) for predicting long-term college success. Outcomes included annual progress towards a degree (based on cumulative credit-bearing hours earned), degree completion, and cumulative grade point average (GPA) at 150% of normal time to degree…

Partially Decentralized Control Architectures for Satellite Formations

Science.gov (United States)

Carpenter, J. Russell; Bauer, Frank H.

2002-01-01

In a partially decentralized control architecture, more than one but less than all nodes have supervisory capability. This paper describes an approach to choosing the number of supervisors in such au architecture, based on a reliability vs. cost trade. It also considers the implications of these results for the design of navigation systems for satellite formations that could be controlled with a partially decentralized architecture. Using an assumed cost model, analytic and simulation-based results indicate that it may be cheaper to achieve a given overall system reliability with a partially decentralized architecture containing only a few supervisors, than with either fully decentralized or purely centralized architectures. Nominally, the subset of supervisors may act as centralized estimation and control nodes for corresponding subsets of the remaining subordinate nodes, and act as decentralized estimation and control peers with respect to each other. However, in the context of partially decentralized satellite formation control, the absolute positions and velocities of each spacecraft are unique, so that correlations which make estimates using only local information suboptimal only occur through common biases and process noise. Covariance and monte-carlo analysis of a simplified system show that this lack of correlation may allow simplification of the local estimators while preserving the global optimality of the maneuvers commanded by the supervisors.

A meta-analysis of the accuracy of the Addenbrooke's Cognitive Examination (ACE) and the Addenbrooke's Cognitive Examination-Revised (ACE-R) in the detection of dementia.

Science.gov (United States)

Larner, Andrew J; Mitchell, Alex J

2014-04-01

The Addenbrooke's Cognitive Examination (ACE) and its Revised version (ACE-R) are relatively new screening tools for cognitive impairment that may improve upon the well-known Mini-Mental State Examination (MMSE) and other brief batteries. We systematically reviewed diagnostic accuracy studies of ACE and ACE-R. Published studies comparing ACE, ACE-R and MMSE were comprehensively sought and critically appraised. A meta-analysis of suitable studies was conducted. Of 61 possible publications identified, meta-analysis of qualifying studies encompassed 5 for ACE (1,090 participants) and 5 for ACE-R (1156 participants); of these, 9 made direct comparisons with the MMSE. Sensitivity and specificity of the ACE were 96.9% (95% CI = 92.7% to 99.4%) and 77.4% (95% CI = 58.3% to 91.8%); and for the ACE-R were 95.7% (95% CI = 92.2% to 98.2%) and 87.5% (95% CI = 63.8% to 99.4%). In a modest prevalence setting, such as primary care or general hospital settings where the prevalence of dementia may be approximately 25%, overall accuracy of the ACE (0.823) was inferior to ACE-R (0.895) and MMSE (0.882). In high prevalence settings such as memory clinics where the prevalence of dementia may be 50% or higher, overall accuracy again favored ACE-R (0.916) over ACE (0.872) and MMSE (0.895). The ACE-R has somewhat superior diagnostic accuracy to the MMSE while the ACE appears to have inferior accuracy. The ACE-R is recommended in both modest and high prevalence settings. Accuracy of newer versions of the ACE remain to be determined.

Cognitive Processing Hardware Elements

National Research Council Canada - National Science Library

Widrow, Bernard; Eliashberg, Victor; Kamenetsky, Max

2005-01-01

The purpose of this research is to identify and develop cognitive information processing systems and algorithms that can be implemented with novel architectures and devices with the goal of achieving...

Cognitive Computing for Security.

Energy Technology Data Exchange (ETDEWEB)

Debenedictis, Erik [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rothganger, Fredrick [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Aimone, James Bradley [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Marinella, Matthew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Evans, Brian Robert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Warrender, Christina E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Mickel, Patrick [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-12-01

Final report for Cognitive Computing for Security LDRD 165613. It reports on the development of hybrid of general purpose/ne uromorphic computer architecture, with an emphasis on potential implementation with memristors.

Activity in the fronto-parietal network indicates numerical inductive reasoning beyond calculation: An fMRI study combined with a cognitive model.

Science.gov (United States)

Liang, Peipeng; Jia, Xiuqin; Taatgen, Niels A; Borst, Jelmer P; Li, Kuncheng

2016-05-19

Numerical inductive reasoning refers to the process of identifying and extrapolating the rule involved in numeric materials. It is associated with calculation, and shares the common activation of the fronto-parietal regions with calculation, which suggests that numerical inductive reasoning may correspond to a general calculation process. However, compared with calculation, rule identification is critical and unique to reasoning. Previous studies have established the central role of the fronto-parietal network for relational integration during rule identification in numerical inductive reasoning. The current question of interest is whether numerical inductive reasoning exclusively corresponds to calculation or operates beyond calculation, and whether it is possible to distinguish between them based on the activity pattern in the fronto-parietal network. To directly address this issue, three types of problems were created: numerical inductive reasoning, calculation, and perceptual judgment. Our results showed that the fronto-parietal network was more active in numerical inductive reasoning which requires more exchanges between intermediate representations and long-term declarative knowledge during rule identification. These results survived even after controlling for the covariates of response time and error rate. A computational cognitive model was developed using the cognitive architecture ACT-R to account for the behavioral results and brain activity in the fronto-parietal network.

Architecture of absurd (forms, positions, apposition

Directory of Open Access Journals (Sweden)

Fedorov Viktor Vladimirovich

2014-04-01

Full Text Available In everyday life we constantly face absurd things, which seem to lack common sense. The notion of the absurd acts as: a an aesthetic category; b an element of logic; c a metaphysical phenomenon. The opportunity of its overcoming is achieved through the understanding of the situation, the faith in the existence of sense and hope for his understanding. The architecture of absurd should be considered as a loss of sense of a part of architectural landscape (urban environment. The ways of organization of the architecture of absurd: the exaggerated forms and proportions, the unnatural position and apposition of various objects. These are usually small-scale facilities that have local spatial and temporary value. There are no large absurd architectural spaces, as the natural architectural environment dampens the perturbation of sense-sphere. The architecture of absurd is considered «pathology» of the environment. «Nonsense» objects and hope (or even faith to detect sense generate a fruitful paradox of architecture of absurd presence in the world.

A conceptual linkage between cognitive architectures and social interaction

NARCIS (Netherlands)

Zoethout, K.; Jager, W.

Cognitive representations are being shaped and determined by interaction with the environment. The social environment constitutes an important part of this environment. Yet in formal models of cognition, there is little attention for processes resulting from social interaction. On the other hand, in

Architectures and Applications for Scalable Quantum Information Systems

Science.gov (United States)

2007-01-01

Gershenfeld and I. Chuang. Quantum computing with molecules. Scientific American, June 1998. [16] A. Globus, D. Bailey, J. Han, R. Jaffe, C. Levit , R...AFRL-IF-RS-TR-2007-12 Final Technical Report January 2007 ARCHITECTURES AND APPLICATIONS FOR SCALABLE QUANTUM INFORMATION SYSTEMS...NUMBER 5b. GRANT NUMBER FA8750-01-2-0521 4. TITLE AND SUBTITLE ARCHITECTURES AND APPLICATIONS FOR SCALABLE QUANTUM INFORMATION SYSTEMS 5c

The Perception of Human Resources Enterprise Architecture within the Department of Defense

Science.gov (United States)

Delaquis, Richard Serge

2012-01-01

The Clinger Cohen Act of 1996 requires that all major Federal Government Information Technology (IT) systems prepare an Enterprise Architecture prior to IT acquisitions. Enterprise Architecture, like house blueprints, represents the system build, capabilities, processes, and data across the enterprise of IT systems. Enterprise Architecture is used…

An Evolutionary Upgrade of Cognitive Load Theory: Using the Human Motor System and Collaboration to Support the Learning of Complex Cognitive Tasks

Science.gov (United States)

Paas, Fred; Sweller, John

2012-01-01

Cognitive load theory is intended to provide instructional strategies derived from experimental, cognitive load effects. Each effect is based on our knowledge of human cognitive architecture, primarily the limited capacity and duration of a human working memory. These limitations are ameliorated by changes in long-term memory associated with…

NAChR α4β2 subtype and their relation with nicotine addiction, cognition, depression and hyperactivity disorder.

Science.gov (United States)

Laikowski, Manuela M; Reisdorfer, Favero; Moura, Sidnei

2018-04-09

Neuronal α4β2 nAChRs are receptors involved in the role of neurotransmitters regulation and release, and this ionic channel participates in biological process of memory, learning and attention. This work aims review the structure and functioning of the α4β2 nAChR emphasizing its role in the treatment of associated diseases like nicotine addiction and underlying pathologies such as cognition, depression and attention-deficit hyperactivity disorder. The authors realized extensive bibliographic research using the descriptors "Nicotine Receptor α4β2" and "cognition", "depression", "attention-deficit hyperactivity disorder", besides cross-references of the selected articles and after analysis of references in the specific literature. As results, it was found 180 relevant articles presenting the main molecules with affinity to nAChR α4β2 relating to the cited diseases. The α4β2 nAChR subtype is a remarkable therapeutic target since this is the most abundant receptor in the central nervous system. In summary, this review presents perspectives on the pharmacology and therapeutic targeting of α4β2 nAChRs for the treatment of cognition and diseases like nicotine dependence, depression and attention-deficit hyperactivity disorder. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

The protective properties of Act-Belong-Commit indicators against incident depression, anxiety, and cognitive impairment among older Irish adults

DEFF Research Database (Denmark)

Santini, Ziggi Ivan; Koyanagi, Ai; Tyrovolas, Stefanos

2017-01-01

-Belong-Commit and incident depression, anxiety, and cognitive impairment at two-year follow-up. The adjusted model showed that each increase in the number of social/recreational activities (Act) inversely predicted the onset of depression, anxiety, and cognitive impairment. The same was the case for social network...... integration (Belong); that is, being well integrated into social networks was a significant protective factor against all mental health outcomes. Finally, frequency of participation in social/recreational activities (Commit) significantly and inversely predicted the onset of depression and anxiety, while...... two consecutive waves of the Irish Longitudinal Study on Ageing (TILDA) were analyzed. The analytical sample consisted of 6098 adults aged ≥ 50 years. Validated scales for depression, anxiety, and cognitive impairment were used. The number of social/recreational activities engaged in was used...

Radio frequency integrated circuit design for cognitive radio systems

CERN Document Server

Fahim, Amr

2015-01-01

This book fills a disconnect in the literature between Cognitive Radio systems and a detailed account of the circuit implementation and architectures required to implement such systems.  Throughout the book, requirements and constraints imposed by cognitive radio systems are emphasized when discussing the circuit implementation details.  In addition, this book details several novel concepts that advance state-of-the-art cognitive radio systems.  This is a valuable reference for anybody with background in analog and radio frequency (RF) integrated circuit design, needing to learn more about integrated circuits requirements and implementation for cognitive radio systems. ·         Describes in detail cognitive radio systems, as well as the circuit implementation and architectures required to implement them; ·         Serves as an excellent reference to state-of-the-art wideband transceiver design; ·         Emphasizes practical requirements and constraints imposed by cognitive radi...

Mapping the Intangible: On Adaptivity and Relational Prototyping in Architectural Design

DEFF Research Database (Denmark)

Bolbroe, Cameline

2016-01-01

In recent years, new computing technologies in architecture have led to the possibility of designing architecture with non-static qualities, which affords the architectural designer with a whole new opportunity space to explore. At the same time, this opportunity space challenges both...... to meet the challenges of designing with adaptivity in architecture, I propose a particular method specifically tailored for adaptive architectural design. The method, relational prototyping, is founded on the idea of inhabitation as an act. Relational prototyping adapts techniques from performance...

Differential diagnosis of depression and Alzheimer's disease with the Addenbrooke's Cognitive Examination-Revised (ACE-R).

Science.gov (United States)

Rotomskis, Augustinas; Margevičiūtė, Ramunė; Germanavičius, Arūnas; Kaubrys, Gintaras; Budrys, Valmantas; Bagdonas, Albinas

2015-04-17

One of the usual problems psychologists and clinicians face in clinical practice is differential diagnostics of Alzheimer's disease and depression. It has been reported that the ACE and ACE-R could discriminate the cognitive dysfunctions due to depression from that due to dementia, although this is not uniform in all studies. The current study aimed to evaluate the utility of the ACE-R to differentiate late-life onset depression (with severe episode) from mild-moderate Alzheimer's Disease (AD). This study received approval from the Lithuanian Bioethics Committee. All participants were older than 50 years (mean age = 66.52 (±8.76) years). The study sample consisted of 295 individuals: 117 with severe depression, 85 with mild-moderate Alzheimer's disease (AD), and 94 age, gender and education matched participants of control group. The ACE-R had high sensitivity (100%) and specificity (81%) at detecting cognitive impairments related to AD. Patients with late-life onset depression (ACE-R mean 76.82, SD = 7.36) performed worse than controls (ACE-R mean 85.08, SD = 7.2), but better than the AD group (ACE-R mean 54.74, SD = 12.19). Participants with late-life onset depression were differentiated by mild impairment in the ACE-R total score with mild memory (13.79, SD = 6.29) and greater deficits in letter fluency (3.65, SD = 1.21) than in semantic fluency (4.68, SD = 1.23). Participants with AD were differentiated by severely impaired performance on attention and orientation (11.80, SD = 2.93), memory (8.25, SD = 3.47) and language subtests (17.21, SD = 4.04), and moderately impaired performance on verbal fluency (6.07, SD = 2.74). ACE-R has diagnostic accuracy in detecting people with AD and can be used in differential diagnostics of late-life onset depression (severe episode) and AD. Diagnostic accuracy may be improved by analyzing the neuropsychological profiles and using lower cutoffs for different age groups.

Advanced control architecture for autonomous vehicles

Science.gov (United States)

Maurer, Markus; Dickmanns, Ernst D.

1997-06-01

An advanced control architecture for autonomous vehicles is presented. The hierarchical architecture consists of four levels: a vehicle level, a control level, a rule-based level and a knowledge-based level. A special focus is on forms of internal representation, which have to be chosen adequately for each level. The control scheme is applied to VaMP, a Mercedes passenger car which autonomously performs missions on German freeways. VaMP perceives the environment with its sense of vision and conventional sensors. It controls its actuators for locomotion and attention focusing. Modules for perception, cognition and action are discussed.

The effect of visual representation style in problem-solving: a perspective from cognitive processes.

Science.gov (United States)

Nyamsuren, Enkhbold; Taatgen, Niels A

2013-01-01

Using results from a controlled experiment and simulations based on cognitive models, we show that visual presentation style can have a significant impact on performance in a complex problem-solving task. We compared subject performances in two isomorphic, but visually different, tasks based on a card game of SET. Although subjects used the same strategy in both tasks, the difference in presentation style resulted in radically different reaction times and significant deviations in scanpath patterns in the two tasks. Results from our study indicate that low-level subconscious visual processes, such as differential acuity in peripheral vision and low-level iconic memory, can have indirect, but significant effects on decision making during a problem-solving task. We have developed two ACT-R models that employ the same basic strategy but deal with different presentations styles. Our ACT-R models confirm that changes in low-level visual processes triggered by changes in presentation style can propagate to higher-level cognitive processes. Such a domino effect can significantly affect reaction times and eye movements, without affecting the overall strategy of problem solving.

The Effect of Visual Representation Style in Problem-Solving: A Perspective from Cognitive Processes

Science.gov (United States)

Nyamsuren, Enkhbold; Taatgen, Niels A.

2013-01-01

Using results from a controlled experiment and simulations based on cognitive models, we show that visual presentation style can have a significant impact on performance in a complex problem-solving task. We compared subject performances in two isomorphic, but visually different, tasks based on a card game of SET. Although subjects used the same strategy in both tasks, the difference in presentation style resulted in radically different reaction times and significant deviations in scanpath patterns in the two tasks. Results from our study indicate that low-level subconscious visual processes, such as differential acuity in peripheral vision and low-level iconic memory, can have indirect, but significant effects on decision making during a problem-solving task. We have developed two ACT-R models that employ the same basic strategy but deal with different presentations styles. Our ACT-R models confirm that changes in low-level visual processes triggered by changes in presentation style can propagate to higher-level cognitive processes. Such a domino effect can significantly affect reaction times and eye movements, without affecting the overall strategy of problem solving. PMID:24260415

The effect of visual representation style in problem-solving: a perspective from cognitive processes.

Directory of Open Access Journals (Sweden)

Enkhbold Nyamsuren

Full Text Available Using results from a controlled experiment and simulations based on cognitive models, we show that visual presentation style can have a significant impact on performance in a complex problem-solving task. We compared subject performances in two isomorphic, but visually different, tasks based on a card game of SET. Although subjects used the same strategy in both tasks, the difference in presentation style resulted in radically different reaction times and significant deviations in scanpath patterns in the two tasks. Results from our study indicate that low-level subconscious visual processes, such as differential acuity in peripheral vision and low-level iconic memory, can have indirect, but significant effects on decision making during a problem-solving task. We have developed two ACT-R models that employ the same basic strategy but deal with different presentations styles. Our ACT-R models confirm that changes in low-level visual processes triggered by changes in presentation style can propagate to higher-level cognitive processes. Such a domino effect can significantly affect reaction times and eye movements, without affecting the overall strategy of problem solving.

Generalized Information Architecture for Managing Requirements in IBM?s Rational DOORS(r) Application.

Energy Technology Data Exchange (ETDEWEB)

Aragon, Kathryn M.; Eaton, Shelley M.; McCornack, Marjorie Turner; Shannon, Sharon A.

2014-12-01

When a requirements engineering effort fails to meet expectations, often times the requirements management tool is blamed. Working with numerous project teams at Sandia National Laboratories over the last fifteen years has shown us that the tool is rarely the culprit; usually it is the lack of a viable information architecture with well- designed processes to support requirements engineering. This document illustrates design concepts with rationale, as well as a proven information architecture to structure and manage information in support of requirements engineering activities for any size or type of project. This generalized information architecture is specific to IBM's Rational DOORS (Dynamic Object Oriented Requirements System) software application, which is the requirements management tool in Sandia's CEE (Common Engineering Environment). This generalized information architecture can be used as presented or as a foundation for designing a tailored information architecture for project-specific needs. It may also be tailored for another software tool. Version 1.0 4 November 201

Common Variance Among Three Measures of Nonverbal Cognitive Ability: WISC-R Performance Scale, WJPB-TCA Reasoning Cluster, and Halstead Category Test.

Science.gov (United States)

Telzrow, Cathy F.; Harr, Gale A.

1987-01-01

Examined the relationships among two psychometric measures of nonverbal cognitive ability - The Wechsler Intelligence Scale for Children-Revised (WISC-R) and the Woodcock-Johnson Psychoeducational Battery-Tests of Cognitive Ability (WJPB-TCA) and a neuropsychological test of abstract reasoning and concept formation (Halstead Category Test) in 25…

A Cognitive Architecture Using Reinforcement Learning to Enable Autonomous Spacecraft Operations, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — We propose an architecture to enable the modular development and deployment of autonomous intelligent agents in support of spacecraft operations. This architecture...

A functional MiR-124 binding-site polymorphism in IQGAP1 affects human cognitive performance.

Directory of Open Access Journals (Sweden)

Lixin Yang

Full Text Available As a product of the unique evolution of the human brain, human cognitive performance is largely a collection of heritable traits. Rather surprisingly, to date there have been no reported cases to highlight genes that underwent adaptive evolution in humans and which carry polymorphisms that have a marked effect on cognitive performance. IQ motif containing GTPase activating protein 1 (IQGAP1, a scaffold protein, affects learning and memory in a dose-dependent manner. Its expression is regulated by miR-124 through the binding sites in the 3'UTR, where a SNP (rs1042538 exists in the core-binding motif. Here we showed that this SNP can influence the miR-target interaction both in vitro and in vivo. Individuals carrying the derived T alleles have higher IQGAP1 expression in the brain as compared to the ancestral A allele carriers. We observed a significant and male-specific association between rs1042538 and tactile performances in two independent cohorts. Males with the derived allele displayed higher tactual performances as compared to those with the ancestral allele. Furthermore, we found a highly diverged allele-frequency distribution of rs1042538 among world human populations, likely caused by natural selection and/or recent population expansion. These results suggest that current human populations still carry sequence variations that affect cognitive performances and that these genetic variants may likely have been subject to comparatively recent natural selection.

COGNITIVE SYSTEMS. REDEFINING THE COOPERATION BETWEEN MAN AND SYSTEM

Directory of Open Access Journals (Sweden)

Diana-Aderina MOISUC

2016-12-01

Full Text Available Cognitive systems appeared as a response to the real challenges brought by the Big Data phenomenon. It was found that the solutions for solving difficult problems caused by this phenomenon could be brought by using artificial intelligence tools. In this context a convergence between Big Data and Artificial Intelligence happened, which determined the start of a new stage in system development, namely the era of cognitive systems. The potential of these systems is given by the characteristics that differentiate them from other systems. The cognitive systems offered solutions and were used with success in complex projects from the medical and financial sectors. The architecture of cognitive systems is complex. These systems are designed so that they use artificial intelligence tools when processing source content, producing analytical solutions which can be used in the decision process. In this paper base concepts, the characteristics and architecture of cognitive systems, the benefits brought by the development and use of them were presented.

Les Machines pour le Big Data : Vers une Informatique Quantique et Cognitive.

OpenAIRE

Teboul , Bruno; Amri , Taoufik

2014-01-01

Cet article est une analyse prospective sur les mutations technologiques qui affecteront l’informatique et ses machines dans un avenir proche afin de répondre aux grands défis soulevés par notre société du tout digital. Nous pensons que ces mutations seront à la fois « quantique » et « cognitive ». Nous étayerons notre analyse en revenant sur ce qui fonde encore aujourd’hui nos ordinateurs, à savoir une architecture vieille de plus d’un demi-siècle, qui est responsable des espoirs déchus de l...

Design of a study on suboptimal cognitive acts in the diagnostic process, the effect on patient outcomes and the influence of workload, fatigue and experience of physician

Directory of Open Access Journals (Sweden)

van der Wal Gerrit

2009-04-01

Full Text Available Abstract Background Diagnostic error is an important error type since diagnostic adverse events are regularly judged as being preventable and the consequences are considered to be severe. Existing research often focuses on either diagnostic adverse events or on the errors in diagnostic reasoning. Whether and when an incorrect diagnostic process results in adverse outcomes has not been studied extensively. The present paper describes the design of a study that aims to study the relationship between a suboptimal diagnostic process and patient outcomes. In addition, the role of personal and circumstantial factors on the quality of the diagnostic process will be examined. Methods/Design The research questions were addressed using several data sources. First, the differential diagnosis was assessed concurrently to the diagnostic process. Second, the patient records of 248 patients suffering from shortness of breath were reviewed by expert internists in order to reveal suboptimal cognitive acts and (potential consequences for the patient. The suboptimal cognitive acts were discussed with the treating physicians and classified with the taxonomy of unsafe acts. Third, workload, fatigue and work experience were measured during the physicians work. Workload and fatigue were measured during the physicians shift using the NASA tlx questionnaire on a handheld computer. Physicians participating in the study also answered questions about their work experience. Discussion The design used in this study provides insight into the relationship between suboptimal cognitive acts in the diagnostic process and possible consequences for the patient. Suboptimal cognitive acts in the diagnostic process and its causes can be revealed. Additional measurements of workload, fatigue and experience allow examining the influence of these factors on the diagnostic process. In conclusion, the present design provides a method with which insights in weaknesses of the diagnostic

Children and Robots Learning to Play Hide and Seek

National Research Council Canada - National Science Library

Trafton, J. G; Schultz, Alan C; Perznowski, Dennis; Bugajska, Magdalena D; Adams, William; Cassimatis, Nicholas L; Brock, Derek P

2006-01-01

...., containment, under) and use that information to play a credible game of hide and seek. They model this hypothesis within the ACT-R cognitive architecture and put the model on a robot, which is able to mimic the child's hiding behavior. They also take the "hiding" model and use it as the basis for a "seeking" model. They suggest that using the same representations and procedures that a person uses allows better interaction between the human and robotic system.

Revisiting nicotine's role in the ageing brain and cognitive impairment

DEFF Research Database (Denmark)

Majdi, Alireza; Kamari, Farzin; Vafaee, Manouchehr Seyedi

2017-01-01

stress, excitotoxicity, amyloid-β toxicity, apoptosis, neuroinflammation, and perturb neurotrophic factors in the brain. Nicotine is an exogenous agonist of nicotinic acetylcholine receptors (nAChRs) and acts as a pharmacological chaperone in the regulation of nAChR expression, potentially intervening...... in age-related changes in diverse molecular pathways leading to pathology. Although nicotine has therapeutic potential, paradoxical effects have been reported, possibly due to its inverted U-shape dose-response effects or pharmacokinetic factors. Additionally, nicotine administration should result...... in optimum therapeutic effects without imparting abuse potential or toxicity. Overall, this review aims to compile the previous and most recent data on nicotine and its effects on cognition-related mechanisms and age-related cognitive impairment....

Coping with instabilities - lessons from Japanese architecture

DEFF Research Database (Denmark)

Greve, Anni

This paper offers insight into the role of architecture in coping with instabilities. At its centre is a second generation of Japanese architects who came to maturity after World War II. They questioned the International Style, and asked for a return to architecture in the image of the early......, a Japanese idea about an ‘in-between’, place and occasion means an ‘in-between’, the Japanese term ma. The final part of the lecture considers ma in its quality as 1) a formula replicated in different cognitive domains, in language, visual perception, abstract ways of reasoning, emotions and actions, and 2...

Social cognition is not associated with cognitive reserve in older adults.

Science.gov (United States)

Lavrencic, Louise M; Kurylowicz, Lisa; Valenzuela, Michael J; Churches, Owen F; Keage, Hannah A D

2016-01-01

Social and general cognitive abilities decline in late life. Those with high cognitive reserve display better general cognitive performance in old age; however, it is unknown whether this is also the case for social cognition. A total of 115 healthy older adults, aged 60-85 years (m = 44, f = 71) were assessed using The Awareness of Social Inference Test (TASIT-R; social cognition), the Lifetime of Experiences Questionnaire (LEQ; cognitive reserve), and the Wechsler Abbreviated Scale of Intelligence (WASI-II; general cognitive ability). The LEQ did not predict performance on any TASIT-R subtest: Emotion Evaluation Test (β = -.097, p = .325), Social Inference - Minimal (β = -.004, p = .972), or Social Inference - Enriched (β = -.016, p = .878). Sensitivity analyses using two alternative cognitive reserve measures, years of education and the National Adult Reading Test, supported these effects. Cognitive reserve was strongly related to WASI-II performance. Unlike general cognitive ability, social cognition appears unaffected by cognitive reserve. Findings contribute to the emerging understanding that cognitive reserve differentially affects individual cognitive domains, which has implications for the theoretical understanding of cognitive reserve and its brain correlates. Cognitive measures unbiased by cognitive reserve may serve as best indicators of brain health, free of compensatory mechanisms.

A Core Knowledge Architecture of Visual Working Memory

Science.gov (United States)

Wood, Justin N.

2011-01-01

Visual working memory (VWM) is widely thought to contain specialized buffers for retaining spatial and object information: a "spatial-object architecture." However, studies of adults, infants, and nonhuman animals show that visual cognition builds on core knowledge systems that retain more specialized representations: (1) spatiotemporal…

Cognitive-Behavioural Therapy

OpenAIRE

Moghaddam, Nima G.; Dawson, David L.

2016-01-01

Cognitive-behavioural therapy (CBT) is a generic term, encompassing both: (1) approaches underpinned by an assumption that presenting emotional and behavioural difficulties are cognitively mediated or moderated; and (2) atheoretical bricolages of cognitive and behavioural techniques. This latter category may include effective therapeutic packages (perhaps acting through mechanisms articulated in the first category) but, when theory is tacit, it becomes harder to make analytical generalisation...

Contribution to comprehending symbolism and meaning of architectural form

Directory of Open Access Journals (Sweden)

Alihodžić Rifat

2017-01-01

Full Text Available Architectural form and space, from the very beginning of their creation, weren’t only elements reflecting mere act of building; as the act of human actions, they included proper symbolic presentation of a creator's perception of the world. The initial point is that each physical, therefore each architectural form, speaks volumes on more than just their purpose, so it can have symbolic meanings, being proved in history of architecture for such a long time. While observing architectural form, these two questions impose. The first question refers to identifying usable purpose of particular facility, in other words, its function. The second question imposes to identify what are the things that we are reminded of concerning that particular facility. This second question represents search for the meaning in each form that mankind instinctively longs to identify in order to comprehend the world we live in. No matter if we are in natural or building area, everything we are surrounded by has got specific forms recalling certain associations. The aim of this paper is to indicate that pictures appearing as a consequence of close forms and designs represent associations and they should not be compared to symbols. The goal of this research is to contribute to clearer seeing of symbolism of architectural form, in which situations it exists and whether it exists in contemporary architectural forms. This work is based on elements of Gestalt observation theory.

Implementation of a Space Communications Cognitive Engine

Science.gov (United States)

Hackett, Timothy M.; Bilen, Sven G.; Ferreira, Paulo Victor R.; Wyglinski, Alexander M.; Reinhart, Richard C.

2017-01-01

Although communications-based cognitive engines have been proposed, very few have been implemented in a full system, especially in a space communications system. In this paper, we detail the implementation of a multi-objective reinforcement-learning algorithm and deep artificial neural networks for the use as a radio-resource-allocation controller. The modular software architecture presented encourages re-use and easy modification for trying different algorithms. Various trade studies involved with the system implementation and integration are discussed. These include the choice of software libraries that provide platform flexibility and promote reusability, choices regarding the deployment of this cognitive engine within a system architecture using the DVB-S2 standard and commercial hardware, and constraints placed on the cognitive engine caused by real-world radio constraints. The implemented radio-resource allocation-management controller was then integrated with the larger spaceground system developed by NASA Glenn Research Center (GRC).

Cognitive screening in substance users: Diagnostic accuracies of the Mini-Mental State Examination, Addenbrooke's Cognitive Examination-Revised, and Montreal Cognitive Assessment.

Science.gov (United States)

Ridley, Nicole; Batchelor, Jennifer; Draper, Brian; Demirkol, Apo; Lintzeris, Nicholas; Withall, Adrienne

2018-03-01

Despite the considerable prevalence of cognitive impairment in substance-using populations, there has been little investigation of the utility of cognitive screening measures within this context. In the present study the accuracy of three cognitive screening measures in this population was examined-the Mini-Mental State Examination (MMSE), the Addenbrooke's Cognitive Examination-Revised (ACE-R), and the Montreal Cognitive Assessment (MoCA). A sample of 30 treatment-seeking substance users and 20 healthy individuals living in the community were administered the screening measures and a neuropsychological battery (NPB). Agreement of classification of cognitive impairment by the screening measures and NPB was examined. Results indicated that the ACE-R and MoCA had good discriminative ability in detection of cognitive impairment, with areas under the receiver-operating characteristic (ROC) curve of .85 (95% confidence interval, CI [.75. .94] and .84 (95% CI [.71, .93]) respectively. The MMSE had fair discriminative ability (.78, 95% CI [.65, .93]). The optimal cut-score for the ACE-R was 93 (impairment = score of 92 or less), at which it correctly classified 89% of individuals as cognitively impaired or intact, while the optimal cut-score for the MoCA was cognitive impairment in the context of substance use.

Predictors of Future Performance in Architectural Design Education

Science.gov (United States)

Roberts, A. S.

2007-01-01

The link between academic performance in secondary education and the subsequent performance of students studying architecture at university level is commonly questioned by educators and admissions tutors. This paper investigates the potential for using measures of cognitive style and spatial ability as predictors of future potential in…

RACE/A : An architectural account of the interactions between learning, task control, and retrieval dynamics

NARCIS (Netherlands)

van Maanen, Leendert; van Rijn, Hedderik; Taatgen, Niels

2012-01-01

This article discusses how sequential sampling models can be integrated in a cognitive architecture. The new theory Retrieval by Accumulating Evidence in an Architecture (RACE/A) combines the level of detail typically provided by sequential sampling models with the level of task complexity typically

Cognitive architectures as a tool for investigating the role of oscillatory power and coherence in cognition

NARCIS (Netherlands)

van Vugt, Marieke K.

2014-01-01

In contrast to our increasing knowledge of the role that oscillations in single brain regions play in cognition, very little is known about how coherence between oscillations in distant brain regions is related to information transmission. Here I present a cognitive modeling approach that can

75 FR 63703 - Privacy Act of 1974; Privacy Act Regulation

Science.gov (United States)

2010-10-18

... FEDERAL RESERVE SYSTEM 12 CFR Part 261a [Docket No. R-1313] Privacy Act of 1974; Privacy Act... implementing the Privacy Act of 1974 (Privacy Act). The primary changes concern the waiver of copying fees... records under the Privacy Act; the amendment of special procedures for the release of medical records to...

The cognitive nature of action - functional links between cognitive psychology, movement science, and robotics.

Science.gov (United States)

Schack, Thomas; Ritter, Helge

2009-01-01

This paper examines the cognitive architecture of human action, showing how it is organized over several levels and how it is built up. Basic action concepts (BACs) are identified as major building blocks on a representation level. These BACs are cognitive tools for mastering the functional demands of movement tasks. Results from different lines of research showed that not only the structure formation of mental representations in long-term memory but also chunk formation in working memory are built up on BACs and relate systematically to movement structures. It is concluded that such movement representations might provide the basis for action implementation and action control in skilled voluntary movements in the form of cognitive reference structures. To simulate action implementation we discuss challenges and issues that arise when we try to replicate complex movement abilities in robots. Among the key issues to be addressed is the question how structured representations can arise during skill acquisition and how the underlying processes can be understood sufficiently succinctly to replicate them on robot platforms. Working towards this goal, we translate our findings in studies of motor control in humans into models that can guide the implementation of cognitive robot architectures. Focusing on the issue of manual action control, we illustrate some results in the context of grasping with a five-fingered anthropomorphic robot hand.

Common Space : Politics and the Production of Architectural Knowledge

NARCIS (Netherlands)

Djalali, A.

2014-01-01

Today we are familiar with definitions of architecture as an integrated, multidisciplinary “networked practice,” which takes its cognitive potential from a “diffused design intelligence.” These definitions were introduced to counter an individual, authorial approach to design which allegedly

A multitasking general executive for compound continuous tasks.

Science.gov (United States)

Salvucci, Dario D

2005-05-06

As cognitive architectures move to account for increasingly complex real-world tasks, one of the most pressing challenges involves understanding and modeling human multitasking. Although a number of existing models now perform multitasking in real-world scenarios, these models typically employ customized executives that schedule tasks for the particular domain but do not generalize easily to other domains. This article outlines a general executive for the Adaptive Control of Thought-Rational (ACT-R) cognitive architecture that, given independent models of individual tasks, schedules and interleaves the models' behavior into integrated multitasking behavior. To demonstrate the power of the proposed approach, the article describes an application to the domain of driving, showing how the general executive can interleave component subtasks of the driving task (namely, control and monitoring) and interleave driving with in-vehicle secondary tasks (radio tuning and phone dialing). 2005 Lawrence Erlbaum Associates, Inc.

Enabling Robotic Social Intelligence by Engineering Human Social-Cognitive Mechanisms

DEFF Research Database (Denmark)

Wiltshire, Travis; Warta, Samantha F.; Barber, Daniel

2017-01-01

for artificial cognitive systems. We discuss a recent integrative perspective of social cognition to provide a systematic theoretical underpinning for computational instantiations of these mechanisms. We highlight several commitments of our approach that we refer to as Engineering Human Social Cognition. We...... then provide a series of recommendations to facilitate the development of the perceptual, motor, and cognitive architecture for this proposed artificial cognitive system in future work. For each recommendation, we highlight their relation to the discussed social-cognitive mechanisms, provide the rationale...

Visual cognition.

Science.gov (United States)

Cavanagh, Patrick

2011-07-01

Visual cognition, high-level vision, mid-level vision and top-down processing all refer to decision-based scene analyses that combine prior knowledge with retinal input to generate representations. The label "visual cognition" is little used at present, but research and experiments on mid- and high-level, inference-based vision have flourished, becoming in the 21st century a significant, if often understated part, of current vision research. How does visual cognition work? What are its moving parts? This paper reviews the origins and architecture of visual cognition and briefly describes some work in the areas of routines, attention, surfaces, objects, and events (motion, causality, and agency). Most vision scientists avoid being too explicit when presenting concepts about visual cognition, having learned that explicit models invite easy criticism. What we see in the literature is ample evidence for visual cognition, but few or only cautious attempts to detail how it might work. This is the great unfinished business of vision research: at some point we will be done with characterizing how the visual system measures the world and we will have to return to the question of how vision constructs models of objects, surfaces, scenes, and events. Copyright © 2011 Elsevier Ltd. All rights reserved.

Letter from A & R Transport about Section 308 of the Clean Water Act Discharge of Perfluorinated Compounds

Science.gov (United States)

January 16, 2009 letter from Kenneth E. Pate, VP of Safety and Risk Management of A & R Transport, Inc. to EPA Clean Water Enforcement Branch, about an Information Request about the Section 308 of the Clean Water Act, discharge of pefluorinated compounds.

TACOP : A cognitive agent for a naval training simulation environment

NARCIS (Netherlands)

Doesburg, W.A. van; Heuvelink, A.; Broek, E.L. van den

2005-01-01

This paper describes how cognitive modeling can be exploited in the design of software agents that support naval training sessions. The architecture, specifications, and embedding of the cognitive agent in a simulation environment are described. Subsequently, the agent's functioning was evaluated in

Architectural considerations for modeling cognitive-emotional decision making

NARCIS (Netherlands)

Lotens, W.A.; Cain, B.

2013-01-01

There are numerous conceptual similarities between affective and rational decision making functions despite the differences between the emotional and cognitive systems. Aspects of emotion may be considered as a concurrent stream of information processing that is coupled with explicit, rational

The Cognitive Assessment Interview (CAI): development and validation of an empirically derived, brief interview-based measure of cognition.

Science.gov (United States)

Ventura, Joseph; Reise, Steven P; Keefe, Richard S E; Baade, Lyle E; Gold, James M; Green, Michael F; Kern, Robert S; Mesholam-Gately, Raquelle; Nuechterlein, Keith H; Seidman, Larry J; Bilder, Robert M

2010-08-01

Practical, reliable "real world" measures of cognition are needed to supplement neurocognitive performance data to evaluate possible efficacy of new drugs targeting cognitive deficits associated with schizophrenia. Because interview-based measures of cognition offer one possible approach, data from the MATRICS initiative (n=176) were used to examine the psychometric properties of the Schizophrenia Cognition Rating Scale (SCoRS) and the Clinical Global Impression of Cognition in Schizophrenia (CGI-CogS). We used classical test theory methods and item response theory to derive the 10-item Cognitive Assessment Interview (CAI) from the SCoRS and CGI-CogS ("parent instruments"). Sources of information for CAI ratings included the patient and an informant. Validity analyses examined the relationship between the CAI and objective measures of cognitive functioning, intermediate measures of cognition, and functional outcome. The rater's score from the newly derived CAI (10 items) correlate highly (r=.87) with those from the combined set of the SCoRS and CGI-CogS (41 items). Both the patient (r=.82) and the informant (r=.95) data were highly correlated with the rater's score. The CAI was modestly correlated with objectively measured neurocognition (r=-.32), functional capacity (r=-.44), and functional outcome (r=-.32), which was comparable to the parent instruments. The CAI allows for expert judgment in evaluating a patient's cognitive functioning and was modestly correlated with neurocognitive functioning, functional capacity, and functional outcome. The CAI is a brief, repeatable, and potentially valuable tool for rating cognition in schizophrenia patients who are participating in clinical trials. Copyright 2010 Elsevier B.V. All rights reserved.

Success in Architecture: Handedness and/or Visual Thinking.

Science.gov (United States)

Peterson, John M.; Lansky, Leonard M.

1980-01-01

Some data on sex and handedness in relation to academic predictors and success in architectural education were reexamined. The new variable was the notion of visual thinking, measured by the manner, "visually" or "cognitively," of executing a simple line drawing. As expected, significant differences appeared between persons using these modes.…

Challenges in comparing the acute cognitive outcomes of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) vs. electroconvulsive therapy (ECT) in major depression: A systematic review.

Science.gov (United States)

Kedzior, Karina Karolina; Schuchinsky, Maria; Gerkensmeier, Imke; Loo, Colleen

2017-08-01

The present study aimed to systematically compare the cognitive outcomes of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) and electroconvulsive therapy (ECT) in head-to-head studies with major depression (MDD) patients. A systematic literature search identified six studies with 219 MDD patients that were too heterogeneous to reliably detect meaningful differences in acute cognitive outcomes after ECT vs. HF-rTMS. Cognitive effects of brain stimulation vary depending on the timeframe and methods of assessment, stimulation parameters, and maintenance treatment. Thus, acute and longer-term differences in cognitive outcomes both need to be investigated at precisely defined timeframes and with similar instruments assessing comparable functions. Copyright © 2017 Elsevier Ltd. All rights reserved.

77 FR 61786 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Heterogeneous...

Science.gov (United States)

2012-10-11

... Production Act of 1993--Heterogeneous System Architecture Foundation Notice is hereby given that, on August..., 15 U.S.C. 4301 et seq. (``the Act''), Heterogeneous System Architecture Foundation (``HSA Foundation... limited to, building and promoting the common business interests of the semiconductor industry by...

Functional specification and architecture of EIAO DW, R2.2

DEFF Research Database (Denmark)

Pedersen, Torben Bach; Thomsen, Christian

In this document, the functional specification and architecture for the EIAO DW is presented. EIAO DW is a data warehouse that holds results from the European Internet Accessibility Observatory (EIAO) project. These results are mainly on the accessibility to disabled users of web resources...

Cooperative and cognitive satellite systems

CERN Document Server

Chatzinotas, Symeon; De Gaudenzi, Riccardo

2015-01-01

Cooperative and Cognitive Satellite Systems provides a solid overview of the current research in the field of cooperative and cognitive satellite systems, helping users understand how to incorporate state-of-the-art communication techniques in innovative satellite network architectures to enable the next generation of satellite systems. The book is edited and written by top researchers and practitioners in the field, providing a comprehensive explanation of current research that allows users to discover future technologies and their applications, integrate satellite and terrestrial systems

Complex architecture of primes and natural numbers.

Science.gov (United States)

García-Pérez, Guillermo; Serrano, M Ángeles; Boguñá, Marián

2014-08-01

Natural numbers can be divided in two nonoverlapping infinite sets, primes and composites, with composites factorizing into primes. Despite their apparent simplicity, the elucidation of the architecture of natural numbers with primes as building blocks remains elusive. Here, we propose a new approach to decoding the architecture of natural numbers based on complex networks and stochastic processes theory. We introduce a parameter-free non-Markovian dynamical model that naturally generates random primes and their relation with composite numbers with remarkable accuracy. Our model satisfies the prime number theorem as an emerging property and a refined version of Cramér's conjecture about the statistics of gaps between consecutive primes that seems closer to reality than the original Cramér's version. Regarding composites, the model helps us to derive the prime factors counting function, giving the probability of distinct prime factors for any integer. Probabilistic models like ours can help to get deeper insights about primes and the complex architecture of natural numbers.

A Scalable Architecture of a Structured LDPC Decoder

Science.gov (United States)

Lee, Jason Kwok-San; Lee, Benjamin; Thorpe, Jeremy; Andrews, Kenneth; Dolinar, Sam; Hamkins, Jon

2004-01-01

We present a scalable decoding architecture for a certain class of structured LDPC codes. The codes are designed using a small (n,r) protograph that is replicated Z times to produce a decoding graph for a (Z x n, Z x r) code. Using this architecture, we have implemented a decoder for a (4096,2048) LDPC code on a Xilinx Virtex-II 2000 FPGA, and achieved decoding speeds of 31 Mbps with 10 fixed iterations. The implemented message-passing algorithm uses an optimized 3-bit non-uniform quantizer that operates with 0.2dB implementation loss relative to a floating point decoder.

Architectural Creation of Light

DEFF Research Database (Denmark)

Bülow, Katja

2015-01-01

Bidraget "Architectural Creation of Light" indgår sammen med 108 andre bidrag i bogen "You Say Light, I Think Shadow". Bogens indhold undersøger: "Hvad er lys". I dette bidrag besvares spørgsmålet gennem iagttagelser af arkitektstuderendes undersøgelser af lyset i deres arbejdsmodeller i...

The bigger, the stronger? Insights from muscle architecture and nervous characteristics in obese adolescent girls.

Science.gov (United States)

Garcia-Vicencio, S; Coudeyre, E; Kluka, V; Cardenoux, C; Jegu, A-G; Fourot, A-V; Ratel, S; Martin, V

2016-02-01

Young obese youth are generally stronger than lean youth. This has been linked to the loading effect of excess body mass, acting as a training stimulus comparable to strength training. Whether this triggers specific adaptations of the muscle architecture (MA) and voluntary activation (VA) that could account for the higher strength of obese subjects remains unknown. MA characteristics (that is, pennation angle (PA), fascicle length (FL) and muscle thickness (MT)) and muscle size (that is, anatomical cross-sectional area (ACSA)) of the knee extensor (KE) and plantar flexor (PF) muscles were evaluated in 12 obese and 12 non-obese adolescent girls (12-15 years). Maximal isometric torque and VA of the KE and PF muscles were also assessed. Results revealed higher PA (Pmuscles in obese girls. Moreover, obese individuals produced a higher absolute torque than their lean counterparts on the KE (224.6±39.5 vs 135.7±32.7 N m, respectively; Pmuscles (73.3±16.5 vs 44.5±6.2 N m; Pmuscles (r=0.45-0.55, P<0.05-0.01). MVC was also correlated with VA (KE: r=0.44, P<0.05; PF: r=0.65, P<0.001) and segmental lean mass (KE: r=0.48, P<0.05; PF: r=0.57, P<0.01). This study highlighted favorable muscular and nervous adaptations to obesity that account for the higher strength of obese youth. The excess of body mass supported during daily activities could act as a chronic training stimulus responsible for these adaptations.

Validation of the Cuban Version of Addenbrooke's Cognitive Examination-Revised for Screening Mild Cognitive Impairment.

Science.gov (United States)

Broche-Pérez, Yunier; López-Pujol, Héctor Alejandro

2017-01-01

The diagnostic accuracy of the Cuban version of the revised Addenbrooke's Cognitive Examination (ACE-R) in identifying mild cognitive impairment (MCI) in comparison with the Mini-Mental State Examination (MMSE) was assessed. The Cuban ACE-R was administered to a group of 129 elderly subjects (92 cognitively healthy and 37 subjects with MCI). The t tests for independent samples were used to compare scores of different psychometric scales between groups, and effect sizes (Cohen's d) were calculated. Cronbach's coefficient α was used to evaluate the reliability of psychometric scales. The validity of ACE-R to screen for MCI was assessed by receiver operating characteristic (ROC) curves. The Cuban ACE-R had reliable internal consistency (Cronbach's coefficient α = 0. 879). The optimal cut-off score for ACE-R for detecting MCI was 84/85. The sensitivity and specificity of ACE-R to screen for MCI was superior to those of MMSE. The area under the ROC curve of the Cuban ACE-R was much larger than that of MMSE (0.93 and 0.63) for detecting MCI. The Cuban ACE-R is a valid screening tool for detecting cognitive impairment. It is more sensitive and accurate in screening for MCI than MMSE. © 2018 S. Karger AG, Basel.

Associative learning and animal cognition.

Science.gov (United States)

Dickinson, Anthony

2012-10-05

Associative learning plays a variety of roles in the study of animal cognition from a core theoretical component to a null hypothesis against which the contribution of cognitive processes is assessed. Two developments in contemporary associative learning have enhanced its relevance to animal cognition. The first concerns the role of associatively activated representations, whereas the second is the development of hybrid theories in which learning is determined by prediction errors, both directly and indirectly through associability processes. However, it remains unclear whether these developments allow associative theory to capture the psychological rationality of cognition. I argue that embodying associative processes within specific processing architectures provides mechanisms that can mediate psychological rationality and illustrate such embodiment by discussing the relationship between practical reasoning and the associative-cybernetic model of goal-directed action.

Histone modifications and nuclear architecture: A review

Czech Academy of Sciences Publication Activity Database

Bártová, Eva; Kroupová, Jana; Harničarová, Andrea; Galiová-Šustáčková, Gabriela; Kozubek, Stanislav

2008-01-01

Roč. 56, č. 8 (2008), s. 711-721 ISSN 0722-186X R&D Projects: GA ČR(CZ) GA204/06/0978; GA MŠk(CZ) LC535 Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702 Keywords : histones * histone modifications * nuclear architecture Subject RIV: BO - Biophysics

Visual cognition

Science.gov (United States)

Cavanagh, Patrick

2011-01-01

Visual cognition, high-level vision, mid-level vision and top-down processing all refer to decision-based scene analyses that combine prior knowledge with retinal input to generate representations. The label “visual cognition” is little used at present, but research and experiments on mid- and high-level, inference-based vision have flourished, becoming in the 21st century a significant, if often understated part, of current vision research. How does visual cognition work? What are its moving parts? This paper reviews the origins and architecture of visual cognition and briefly describes some work in the areas of routines, attention, surfaces, objects, and events (motion, causality, and agency). Most vision scientists avoid being too explicit when presenting concepts about visual cognition, having learned that explicit models invite easy criticism. What we see in the literature is ample evidence for visual cognition, but few or only cautious attempts to detail how it might work. This is the great unfinished business of vision research: at some point we will be done with characterizing how the visual system measures the world and we will have to return to the question of how vision constructs models of objects, surfaces, scenes, and events. PMID:21329719

Addenbrooke's cognitive examination test for brief cognitive assessment of adolescents suffering from migraine with aura.

Science.gov (United States)

Petrusic, Igor; Pavlovski, Vera; Savkovic, Zorica; Vucinic, Dragana; Filipovic, Branislav; Jancic, Jasna

2017-03-01

The aim of this study was to assess the role of the Addenbrooke's cognitive examination test (ACE-R) in the evaluation of cognitive status in migraineurs interictally. A total of 44 adolescent patients and 44 healthy controls, matched by age and gender, have undergone ACE-R testing. Migraineurs were additionally questioned about migraine aura features and presence of higher cortical dysfunctions (HCD) during an aura. According to the questionnaire results, patients were subsequently divided into HCD and Non-HCD group. ACE-R scores of migraine patients were significantly lower than in healthy controls (93.68 ± 3.64 vs 96.91 ± 2.49; t = 4.852, p cognitive examination score, although Non-HCD subgroup achieved better score (93.13 ± 3.91 vs 94.29 ± 3.30; t = 1.053, p = 0.298). Findings have shown that migraineurs get lower ACE-R test scores, with a tendency to have a poorer outcome in more complex aura. Also, our study has revealed that the ACE-R test is an easily administered test for brief assessment of cognitive status in migraineurs. Future perspectives could be further evaluation of ACE-R test in larger sample size and the impact of migraine with aura on cognitive function in adolescents.

Fish cognition

OpenAIRE

Bshary, Redouan; Brown, Culum

2017-01-01

The central nervous system, and the brain in particular, is one of the most remarkable products of evolution. This system allows an individual to acquire, process, store and act on information gathered from the environment. The resulting flexibility in behavior beyond genetically coded strategies is a prime adaptation in animals. The field of animal cognition examines the underlying processes and mechanisms. Fishes are a particularly interesting group of vertebrates to study cognition for two...

From green architecture to architectural green

DEFF Research Database (Denmark)

Earon, Ofri

2011-01-01

that describes the architectural exclusivity of this particular architecture genre. The adjective green expresses architectural qualities differentiating green architecture from none-green architecture. Currently, adding trees and vegetation to the building’s facade is the main architectural characteristics...... they have overshadowed the architectural potential of green architecture. The paper questions how a green space should perform, look like and function. Two examples are chosen to demonstrate thorough integrations between green and space. The examples are public buildings categorized as pavilions. One......The paper investigates the topic of green architecture from an architectural point of view and not an energy point of view. The purpose of the paper is to establish a debate about the architectural language and spatial characteristics of green architecture. In this light, green becomes an adjective...

Language and Cognition

DEFF Research Database (Denmark)

Fusaroli, Riccardo

The Ph.D dissertation “Language and Cognition” addresses the way social uses of language – e.g. on the media, or in conversation – shape the way we think and act. Cognitive sciences have started focusing on embodiment and joint cognition – the way in which cognitive processes are deeply shaped...... interacting, without making place for and relying upon the external world, for its structures, its resistances and its dynamics. Cognition is thus a relational process aimed at - perceiving the regularities and affordances (possibilities for further action, perception and, more generally, cognition...... to linguistic use, but also the effects of these processes on the coordination of other cognitive processes. It involved conceptual and experimental methodologies. Chapter 2 The cognitive study of metaphors largely focuses on showing how abstract thought and language uses are strongly shaped by embodied...

R2 Cognitive Computing

Data.gov (United States)

National Aeronautics and Space Administration — Robonaut 2, a crew assistant robotic prototype, will be integrated with IBM’s Watson. R2 will embody the artificial intelligence to enable new levels of robotic...

Interband cascade (IC) photovoltaic (PV) architecture for PV devices

Science.gov (United States)

Yang, Rui Q.; Tian, Zhaobing; Mishima, Tetsuya D.; Santos, Michael B.; Johnson, Matthew B.; Klem, John F.

2015-10-20

A photovoltaic (PV) device, comprising a PV interband cascade (IC) stage, wherein the IC PV stage comprises an absorption region with a band gap, the absorption region configured to absorb photons, an intraband transport region configured to act as a hole barrier, and an interband tunneling region configured to act as an electron barrier. An IC PV architecture for a photovoltaic device, the IC PV architecture comprising an absorption region, an intraband transport region coupled to the absorption region, and an interband tunneling region coupled to the intraband transport region and to the adjacent absorption region, wherein the absorption region, the intraband transport region, and the interband tunneling region are positioned such that electrons will flow from the absorption region to the intraband transport region to the interband tunneling region.

The prefrontal landscape: implications of functional architecture for understanding human mentation and the central executive.

Science.gov (United States)

Goldman-Rakic, P S

1996-10-29

The functional architecture of prefrontal cortex is central to our understanding of human mentation and cognitive prowess. This region of the brain is often treated as an undifferentiated structure, on the one hand, or as a mosaic of psychological faculties, on the other. This paper focuses on the working memory processor as a specialization of prefrontal cortex and argues that the different areas within prefrontal cortex represent iterations of this function for different information domains, including spatial cognition, object cognition and additionally, in humans, semantic processing. According to this parallel processing architecture, the 'central executive' could be considered an emergent property of multiple domain-specific processors operating interactively. These processors are specializations of different prefrontal cortical areas, each interconnected both with the domain-relevant long-term storage sites in posterior regions of the cortex and with appropriate output pathways.

An Affordability Comparison Tool (ACT) for Space Transportation

Science.gov (United States)

McCleskey, C. M.; Bollo, T. R.; Garcia, J. L.

2012-01-01

NASA bas recently emphasized the importance of affordability for Commercial Crew Development Program (CCDP), Space Launch Systems (SLS) and Multi-Purpose Crew Vehicle (MPCV). System architects and designers are challenged to come up with architectures and designs that do not bust the budget. This paper describes the Affordability Comparison Tool (ACT) analyzes different systems or architecture configurations for affordability that allows for a comparison of: total life cycle cost; annual recurring costs, affordability figures-of-merit, such as cost per pound, cost per seat, and cost per flight, as well as productivity measures, such as payload throughput. Although ACT is not a deterministic model, the paper develops algorithms and parametric factors that use characteristics of the architectures or systems being compared to produce important system outcomes (figures-of-merit). Example applications of outcome figures-of-merit are also documented to provide the designer with information on the relative affordability and productivity of different space transportation applications.

Computer-aided cognitive rehabilitation improves cognitive performances and induces brain functional connectivity changes in relapsing remitting multiple sclerosis patients: an exploratory study.

Science.gov (United States)

Bonavita, S; Sacco, R; Della Corte, M; Esposito, S; Sparaco, M; d'Ambrosio, A; Docimo, R; Bisecco, A; Lavorgna, L; Corbo, D; Cirillo, S; Gallo, A; Esposito, F; Tedeschi, G

2015-01-01

To better understand the effects of short-term computer-based cognitive rehabilitation (cCR) on cognitive performances and default mode network (DMN) intrinsic functional connectivity (FC) in cognitively impaired relapsing remitting (RR) multiple sclerosis (MS) patients. Eighteen cognitively impaired RRMS patients underwent neuropsychological evaluation by the Rao's brief repeatable battery and resting-state functional magnetic resonance imaging to evaluate FC of the DMN before and after a short-term (8 weeks, twice a week) cCR. A control group of 14 cognitively impaired RRMS patients was assigned to an aspecific cognitive training (aCT), and underwent the same study protocol. Correlations between DMN and cognitive performances were also tested. After cCR, there was a significant improvement of the following tests: SDMT (p Color-Word Interference Test and FC in the PCC emerged. After aCT, the control group did not show any significant effect either on FC or neuropsychological tests. No significant differences were found in brain volumes and lesion load in both groups when comparing data acquired at baseline and after cCR or aCT. In cognitively impaired RRMS patients, cCR improves cognitive performances (i.e., processing speed and visual and verbal sustained memory), and increases FC in the PCC and IPC of the DMN. This exploratory study suggests that cCR may induce adaptive cortical reorganization favoring better cognitive performances, thus strengthening the value of cognitive exercise in the general perspective of building either cognitive or brain reserve.

Anticipatory Cognitive Systems: a Theoretical Model

Science.gov (United States)

Terenzi, Graziano

This paper deals with the problem of understanding anticipation in biological and cognitive systems. It is argued that a physical theory can be considered as biologically plausible only if it incorporates the ability to describe systems which exhibit anticipatory behaviors. The paper introduces a cognitive level description of anticipation and provides a simple theoretical characterization of anticipatory systems on this level. Specifically, a simple model of a formal anticipatory neuron and a model (i.e. the τ-mirror architecture) of an anticipatory neural network which is based on the former are introduced and discussed. The basic feature of this architecture is that a part of the network learns to represent the behavior of the other part over time, thus constructing an implicit model of its own functioning. As a consequence, the network is capable of self-representation; anticipation, on a oscopic level, is nothing but a consequence of anticipation on a microscopic level. Some learning algorithms are also discussed together with related experimental tasks and possible integrations. The outcome of the paper is a formal characterization of anticipation in cognitive systems which aims at being incorporated in a comprehensive and more general physical theory.

Architecture on Architecture

DEFF Research Database (Denmark)

Olesen, Karen

2016-01-01

that is not scientific or academic but is more like a latent body of data that we find embedded in existing works of architecture. This information, it is argued, is not limited by the historical context of the work. It can be thought of as a virtual capacity – a reservoir of spatial configurations that can...... correlation between the study of existing architectures and the training of competences to design for present-day realities.......This paper will discuss the challenges faced by architectural education today. It takes as its starting point the double commitment of any school of architecture: on the one hand the task of preserving the particular knowledge that belongs to the discipline of architecture, and on the other hand...

A Security Architecture for Fault-Tolerant Systems

Science.gov (United States)

1993-06-03

aspect of our effort to achieve better performance is integrating the system into microkernel -based operating systems. 4 Summary and discussion In...135-171, June 1983. [vRBC+92] R. van Renesse, K. Birman, R. Cooper, B. Glade, and P. Stephenson. Reliable multicast between microkernels . In...Proceedings of the USENIX Microkernels and Other Kernel Architectures Workshop, April 1992. 29

An agent architecture with on-line learning of both procedural and declarative knowledge

Energy Technology Data Exchange (ETDEWEB)

Sun, R.; Peterson, T.; Merrill, E. [Univ. of Alabama, Tuscaloosa, AL (United States)

1996-12-31

In order to develop versatile cognitive agents that learn in situated contexts and generalize resulting knowledge to different environments, we explore the possibility of learning both declarative and procedural knowledge in a hybrid connectionist architecture. The architecture is based on the two-level idea proposed earlier by the author. Declarative knowledge is represented symbolically, while procedural knowledge is represented subsymbolically. The architecture integrates reactive procedures, rules, learning, and decision-making in a unified framework, and structures different learning components (including Q-learning and rule induction) in a synergistic way to perform on-line and integrated learning.

Architecture for the silvering society

DEFF Research Database (Denmark)

Andersson, Jonas E; Rönn, Magnus

Abstract In the context of the universal ageing process that is currently taking place in western society, the organization of architecture competitions that deals with space for dependent ageing comes of relevance. Based on the welfare regime theory, it could be argued that this type of architec......Abstract In the context of the universal ageing process that is currently taking place in western society, the organization of architecture competitions that deals with space for dependent ageing comes of relevance. Based on the welfare regime theory, it could be argued that this type...... by the Swedish Institute of Assistive Technology (SIAT), which administered the governmental allocation of 50 million SEK. The research material was accumulated by use of internet searches, interviews and questionnaires. The analysis applied pattern seeking and involved close reading, document analysis...... on ageing, eldercare and space. Consequently, architecture competitions that focus on the emerging ageing society could be seen as a restrained type of space for architects to digress. National welfare goals and existing means to achieve these goals act as inhibitors for an innovative spatial preparation...

A Cognitive Neural Architecture Able to Learn and Communicate through Natural Language.

Directory of Open Access Journals (Sweden)

Bruno Golosio

Full Text Available Communicative interactions involve a kind of procedural knowledge that is used by the human brain for processing verbal and nonverbal inputs and for language production. Although considerable work has been done on modeling human language abilities, it has been difficult to bring them together to a comprehensive tabula rasa system compatible with current knowledge of how verbal information is processed in the brain. This work presents a cognitive system, entirely based on a large-scale neural architecture, which was developed to shed light on the procedural knowledge involved in language elaboration. The main component of this system is the central executive, which is a supervising system that coordinates the other components of the working memory. In our model, the central executive is a neural network that takes as input the neural activation states of the short-term memory and yields as output mental actions, which control the flow of information among the working memory components through neural gating mechanisms. The proposed system is capable of learning to communicate through natural language starting from tabula rasa, without any a priori knowledge of the structure of phrases, meaning of words, role of the different classes of words, only by interacting with a human through a text-based interface, using an open-ended incremental learning process. It is able to learn nouns, verbs, adjectives, pronouns and other word classes, and to use them in expressive language. The model was validated on a corpus of 1587 input sentences, based on literature on early language assessment, at the level of about 4-years old child, and produced 521 output sentences, expressing a broad range of language processing functionalities.

Chapitre IX. On the representation of contemporary Greek architecture

OpenAIRE

Petridou, Vassiliki; Constantopoulos, Elias

2014-01-01

La question que nous nous apprêtons à approfondir à la lumière de cette étude revêt un double aspect. Le premier est une réflexion sur les caractères de représentation urbaine tels que définis par Leon Battista Alberti dans De re aedificatoria (un des textes fondateurs de l’architecture de la Renaissance et, de manière plus générale, de l’architecture moderne). Le second concerne plus directement le projet urbain. En effet, parallèlement à la rédaction d’un texte de comparaison entre Alberti ...

Ephemeral architecture and scenographies of francoist propaganda during the Spanish Civil War

Directory of Open Access Journals (Sweden)

Amparo Bernal López-Sanvicente

2018-05-01

Full Text Available In Franco’s provisional government established during the war, the Department of Plastic Arts of the National Propaganda Service brought together a small group of plastic artists who had the opportunity of being relieved of military duty in order to create the image of the “New State”. The Architecture Section of this department was in charge of designing the architecture and scenography required for the acts and ceremonies of the government in order to show a city dignified by the new social order. This architecture of propaganda designed during the war was ephemeral and a mere stage setting, but likewise during this period another architecture was built under military initiative, aimed at consolidating the formal stereotype of Franco period propaganda architecture.

Fractal analysis of bone architecture at distal radius

International Nuclear Information System (INIS)

Tomomitsu, Tatsushi; Mimura, Hiroaki; Murase, Kenya; Sone, Teruki; Fukunaga, Masao

2005-01-01

Bone strength depends on bone quality (architecture, turnover, damage accumulation, and mineralization) as well as bone mass. In this study, human bone architecture was analyzed using fractal image analysis, and the clinical relevance of this method was evaluated. The subjects were 12 healthy female controls and 16 female patients suspected of having osteoporosis (age range, 22-70 years; mean age, 49.1 years). High-resolution CT images of the distal radius were acquired and analyzed using a peripheral quantitative computed tomography (pQCT) system. On the same day, bone mineral densities of the lumbar spine (L-BMD), proximal femur (F-BMD), and distal radius (R-BMD) were measured by dual-energy X-ray absorptiometry (DXA). We examined the correlation between the fractal dimension and six bone mass indices. Subjects diagnosed with osteopenia or osteoporosis were divided into two groups (with and without vertebral fracture), and we compared measured values between these two groups. The fractal dimension correlated most closely with L-BMD (r=0.744). The coefficient of correlation between the fractal dimension and L-BMD was very similar to the coefficient of correlation between L-BMD and F-BMD (r=0.783) and the coefficient of correlation between L-BMD and R-BMD (r=0.742). The fractal dimension was the only measured value that differed significantly between both the osteopenic and the osteoporotic subjects with and without vertebral fracture. The present results suggest that the fractal dimension of the distal radius can be reliably used as a bone strength index that reflects bone architecture as well as bone mass. (author)

Addenbrooke's Cognitive Examination and Individual Domain Cut-Off Scores for Discriminating between Different Cognitive Subtypes of Parkinson's Disease.

Science.gov (United States)

Berankova, Dagmar; Janousova, Eva; Mrackova, Martina; Eliasova, Ilona; Kostalova, Milena; Skutilova, Svetlana; Rektorova, Irena

2015-01-01

Objective. The main aim of this study was to verify the sensitivity and specificity of Addenbrooke's Cognitive Examination-Revised (ACE-R) in discriminating between Parkinson's disease (PD) with normal cognition (PD-NC) and PD with mild cognitive impairment (PD-MCI) and between PD-MCI and PD with dementia (PD-D). We also evaluated how ACE-R correlates with neuropsychological cognitive tests in PD. Methods. We examined three age-matched groups of PD patients diagnosed according to the Movement Disorder Society Task Force criteria: PD-NC, PD-MCI, and PD-D. ROC analysis was used to establish specific cut-off scores of ACE-R and its domains. Correlation analyses were performed between ACE-R and its subtests with relevant neuropsychological tests. Results. Statistically significant differences between groups were demonstrated in global ACE-R scores and subscores, except in the language domain. ACE-R cut-off score of 88.5 points discriminated best between PD-MCI and PD-NC (sensitivity 0.68, specificity 0.91); ACE-R of 82.5 points distinguished best between PD-MCI and PD-D (sensitivity 0.70, specificity 0.73). The verbal fluency domain of ACE-R demonstrated the best discrimination between PD-NC and PD-MCI (cut-off score 11.5; sensitivity 0.70, specificity 0.73) while the orientation/attention subscore was best between PD-MCI and PD-D (cut-off score 15.5; sensitivity 0.90, specificity 0.97). ACE-R scores except for ACE-R language correlated with specific cognitive tests of interest.

Trends in Microfabrication Capabilities & Device Architectures.

Energy Technology Data Exchange (ETDEWEB)

Bauer, Todd [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Adam [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lentine, Tony [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Mudrick, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Okandan, Murat [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rodrigues, Arun [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-06-01

The last two decades have seen an explosion in worldwide R&D, enabling fundamentally new capabilities while at the same time changing the international technology landscape. The advent of technologies for continued miniaturization and electronics feature size reduction, and for architectural innovations, will have many technical, economic, and national security implications. It is important to anticipate possible microelectronics development directions and their implications on US national interests. This report forecasts and assesses trends and directions for several potentially disruptive microfabrication capabilities and device architectures that may emerge in the next 5-10 years.

Rational Adaptation under Task and Processing Constraints: Implications for Testing Theories of Cognition and Action

Science.gov (United States)

Howes, Andrew; Lewis, Richard L.; Vera, Alonso

2009-01-01

The authors assume that individuals adapt rationally to a utility function given constraints imposed by their cognitive architecture and the local task environment. This assumption underlies a new approach to modeling and understanding cognition--cognitively bounded rational analysis--that sharpens the predictive acuity of general, integrated…

Integrated, Not Isolated: Defining Typological Proximity in an Integrated Multilingual Architecture

Directory of Open Access Journals (Sweden)

Michael T. Putnam

2018-01-01

Full Text Available On the surface, bi- and multilingualism would seem to be an ideal context for exploring questions of typological proximity. The obvious intuition is that the more closely related two languages are, the easier it should be to implement the two languages in one mind. This is the starting point adopted here, but we immediately run into the difficulty that the overwhelming majority of cognitive, computational, and linguistic research on bi- and multilingualism exhibits a monolingual bias (i.e., where monolingual grammars are used as the standard of comparison for outputs from bilingual grammars. The primary questions so far have focused on how bilinguals balance and switch between their two languages, but our perspective on typology leads us to consider the nature of bi- and multi-lingual systems as a whole. Following an initial proposal from Hsin (2014, we conjecture that bilingual grammars are neither isolated, nor (completely conjoined with one another in the bilingual mind, but rather exist as integrated source grammars that are further mitigated by a common, combined grammar (Cook, 2016; Goldrick et al., 2016a,b; Putnam and Klosinski, 2017. Here we conceive such a combined grammar in a parallel, distributed, and gradient architecture implemented in a shared vector-space model that employs compression through routinization and dimensionality reduction. We discuss the emergence of such representations and their function in the minds of bilinguals. This architecture aims to be consistent with empirical results on bilingual cognition and memory representations in computational cognitive architectures.

The Double R Theory of Language Comprehension

National Research Council Canada - National Science Library

Ball, Jerry

2004-01-01

... (also known as Cognitive Semantics). This technical report explicates the basic principles and assumptions of Double R Grammar and compares Double R Grammar to Chomsky's X-Bar Theory as well as Langacker's Cognitive Linguistic...

A SOCIO-COGNITIVE APPROACH TO KNOWLEDGE CONSTRUCTION THROUGH BLENDED LEARNING

Directory of Open Access Journals (Sweden)

Tuba Kocaturk

2017-01-01

Full Text Available This paper results from an educational research project that was undertaken by the School of Architecture, at the University of Liverpool funded by the Higher Education Academy in UK. The research explored technology driven shifts in architectural design studio education, identified their cognitive effects on design learning and developed an innovative blended learning approach that was implemented at a masters level digital design studio. The contribution of the research and the proposed approach to the existing knowledge and practice are twofold. Firstly, it offers a new pedagogical framework which integrates social, technical and cognitive dimensions of knowledge construction. And secondly, it offers a unique operational model through the integration of both mediational and instrumental use of digital media. The proposed model provides a useful basis for the effective mobilization of next generation learning technologies which can effectively respond to the learning challenges specific to architectural design knowledge and its means of creation.

Modularity, comparative cognition and human uniqueness.

Science.gov (United States)

Shettleworth, Sara J

2012-10-05

Darwin's claim 'that the difference in mind between man and the higher animals … is certainly one of degree and not of kind' is at the core of the comparative study of cognition. Recent research provides unprecedented support for Darwin's claim as well as new reasons to question it, stimulating new theories of human cognitive uniqueness. This article compares and evaluates approaches to such theories. Some prominent theories propose sweeping domain-general characterizations of the difference in cognitive capabilities and/or mechanisms between adult humans and other animals. Dual-process theories for some cognitive domains propose that adult human cognition shares simple basic processes with that of other animals while additionally including slower-developing and more explicit uniquely human processes. These theories are consistent with a modular account of cognition and the 'core knowledge' account of children's cognitive development. A complementary proposal is that human infants have unique social and/or cognitive adaptations for uniquely human learning. A view of human cognitive architecture as a mosaic of unique and species-general modular and domain-general processes together with a focus on uniquely human developmental mechanisms is consistent with modern evolutionary-developmental biology and suggests new questions for comparative research.

Simple substrates for complex cognition

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Peter Dayan

2008-12-01

Full Text Available Complex cognitive tasks present a range of computational and algorithmic challenges for neural accounts of both learning and inference. In particular, it is extremely hard to solve them using the sort of simple policies that have been extensively studied as solutions to elementary Markov decision problems. There has thus been recent interest in architectures for the instantiation and even learning of policies that are formally more complicated than these, involving operations such as gated working memory. However, the focus of these ideas and methods has largely been on what might best be considered as automatized, routine or, in the sense of animal conditioning, habitual, performance. Thus, they have yet to provide a route towards understanding the workings of rule-based control, which is critical for cognitively sophisticated competence. Here, we review a recent suggestion for a uniform architecture for habitual and rule-based execution, discuss some of the habitual mechanisms that underpin the use of rules, and consider a statistical relationship between rules and habits.

The CaV2.3 R-type voltage-gated Ca2+ channel in mouse sleep architecture.

Science.gov (United States)

Siwek, Magdalena Elisabeth; Müller, Ralf; Henseler, Christina; Broich, Karl; Papazoglou, Anna; Weiergräber, Marco

2014-05-01

Voltage-gated Ca(2+) channels (VGCCs) are key elements in mediating thalamocortical rhythmicity. Low-voltage activated (LVA) CaV 3 T-type Ca(2+) channels have been related to thalamic rebound burst firing and to generation of non-rapid eye movement (NREM) sleep. High-voltage activated (HVA) CaV 1 L-type Ca(2+) channels, on the opposite, favor the tonic mode of action associated with higher levels of vigilance. However, the role of the HVA Non-L-type CaV2.3 Ca(2+) channels, which are predominantly expressed in the reticular thalamic nucleus (RTN), still remains unclear. Recently, CaV2.3(-/-) mice were reported to exhibit altered spike-wave discharge (SWD)/absence seizure susceptibility supported by the observation that CaV2.3 mediated Ca(2+) influx into RTN neurons can trigger small-conductance Ca(2+)-activated K(+)-channel type 2 (SK2) currents capable of maintaining thalamic burst activity. Based on these studies we investigated the role of CaV2.3 R-type Ca(2+) channels in rodent sleep. The role of CaV2.3 Ca(2+) channels was analyzed in CaV2.3(-/-) mice and controls in both spontaneous and artificial urethane-induced sleep, using implantable video-EEG radiotelemetry. Data were analyzed for alterations in sleep architecture using sleep staging software and time-frequency analysis. CaV2.3 deficient mice exhibited reduced wake duration and increased slow-wave sleep (SWS). Whereas mean sleep stage durations remained unchanged, the total number of SWS epochs was increased in CaV2.3(-/-) mice. Additional changes were observed for sleep stage transitions and EEG amplitudes. Furthermore, urethane-induced SWS mimicked spontaneous sleep results obtained from CaV2.3 deficient mice. Quantitative Real-time PCR did not reveal changes in thalamic CaV3 T-type Ca(2+) channel expression. The detailed mechanisms of SWS increase in CaV2.3(-/-) mice remain to be determined. Low-voltage activated CaV2.3 R-type Ca(2+) channels in the thalamocortical loop and extra

An extensible database architecture for nationwide power quality monitoring

Energy Technology Data Exchange (ETDEWEB)

Kuecuek, Dilek; Inan, Tolga; Salor, Oezguel; Demirci, Turan; Buhan, Serkan; Boyrazoglu, Burak [TUBITAK Uzay, Power Electronics Group, TR 06531 Ankara (Turkey); Akkaya, Yener; Uensar, Oezguer; Altintas, Erinc; Haliloglu, Burhan [Turkish Electricity Transmission Co. Inc., TR 06490 Ankara (Turkey); Cadirci, Isik [TUBITAK Uzay, Power Electronics Group, TR 06531 Ankara (Turkey); Hacettepe University, Electrical and Electronics Eng. Dept., TR 06532 Ankara (Turkey); Ermis, Muammer [METU, Electrical and Electronics Eng. Dept., TR 06531 Ankara (Turkey)

2010-07-15

Electrical power quality (PQ) data is one of the prevalent types of engineering data. Its measurement at relevant sampling rates leads to large volumes of PQ data to be managed and analyzed. In this paper, an extensible database architecture is presented based on a novel generic data model for PQ data. The proposed architecture is operated on the nationwide PQ data of the Turkish Electricity Transmission System measured in the field by mobile PQ monitoring systems. The architecture is extensible in the sense that it can be used to store and manage PQ data collected by any means with little or no customization. The architecture has three modules: a PQ database corresponding to the implementation of the generic data model, a visual user query interface to enable its users to specify queries to the PQ database and a query processor acting as a bridge between the query interface and the database. The operation of the architecture is illustrated on the field PQ data with several query examples through the visual query interface. The execution of the architecture on this data of considerable volume supports its applicability and convenience for PQ data. (author)

77 FR 50068 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles

Science.gov (United States)

2012-08-20

... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD 36 CFR Part 1192 [Docket No. ATBCB 2010-0004] RIN 3014-AA38 Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles AGENCY: Architectural and Transportation Barriers Compliance Board. ACTION: Notice of public...

77 FR 56590 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles

Science.gov (United States)

2012-09-13

... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD 36 CFR Part 1192 [Docket No. ATBCB 2010-0004] RIN 3014-AA38 Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles AGENCY: Architectural and Transportation Barriers Compliance Board. ACTION: Notice of information...

75 FR 54543 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles

Science.gov (United States)

2010-09-08

... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD 36 CFR Part 1192 [Docket No. ATBCB 2010-0004] RIN 3014-AA38 Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles AGENCY: Architectural and Transportation Barriers Compliance Board. ACTION: Notice of public...

The AORTA Architecture: Integrating Organizational Reasoning in Jason

DEFF Research Database (Denmark)

Jensen, Andreas Schmidt; Dignum, Virginia; Villadsen, Jørgen

2014-01-01

the expected behavior of the agents. Agents need to be able to reason about the regulations, so that they can act within the expected boundaries and work towards the objectives of the organization. In this paper, we describe the AORTA (Adding Organizational Reasoning to Agents) architecture for making agents...

Evolutionary Effect on the Embodied Beauty of Landscape Architectures.

Science.gov (United States)

Zhang, Wei; Tang, Xiaoxiang; He, Xianyou; Chen, Guangyao

2018-01-01

According to the framework of evolutionary aesthetics, a sense of beauty is related to environmental adaptation and plasticity of human beings, which has adaptive value and biological foundations. Prior studies have demonstrated that organisms derive benefits from the landscape. In this study, we investigated whether the benefits of landscape might elicit a stronger sense of beauty and what the nature of this sense of beauty is. In two experiments, when viewing classical landscape and nonlandscape architectures photographs, participants rated the aesthetic scores (Experiment 1) and had a two-alternative forced choice aesthetic judgment by pressing the reaction button located near to (15 cm) or far from (45 cm) the presenting stimuli (Experiment 2). The results showed that reaction of aesthetic ratings for classical landscape architectures was faster than those of classical nonlandscape architectures. Furthermore, only the reaction of beautiful judgment of classical landscape architecture photograph was significantly faster when the reaction button was in the near position to the presenting photograph than those in the position of far away from the presenting photograph. This finding suggests a facilitated effect for the aesthetic perception of classical landscape architectures due to their corresponding components including water and green plants with strong evolutionary implications. Furthermore, this sense of beauty for classical landscape architectures might be the embodied approach to beauty based on the viewpoint of evolutionary aesthetics and embodied cognition.

Microporous calcium phosphate ceramics driving osteogenesis through surface architecture.

Science.gov (United States)

Zhang, Jingwei; Barbieri, Davide; ten Hoopen, Hetty; de Bruijn, Joost D; van Blitterswijk, Clemens A; Yuan, Huipin

2015-03-01

The presence of micropores in calcium phosphate (CaP) ceramics has shown its important role in initiating inductive bone formation in ectopic sites. To investigate how microporous CaP ceramics trigger osteoinduction, we optimized two biphasic CaP ceramics (i.e., BCP-R and BCP-S) to have the same chemical composition, equivalent surface area per volume, comparable protein adsorption, similar ion (i.e., calcium and phosphate) exchange and the same surface mineralization potential, but different surface architecture. In particular, BCP-R had a surface roughness (Ra) of 325.4 ± 58.9 nm while for BCP-S it was 231.6 ± 35.7 nm. Ceramic blocks with crossing or noncrossing channels of 250, 500, 1000, and 2000 µm were implanted in paraspinal muscle of dogs for 12 weeks. The percentage of bone volume in the channels was not affected by the type of pores (i.e., crossing vs. closed) or their size, but it was greatly influenced by the ceramic type (i.e., BCP-R vs. BCP-S). Significantly, more bone was formed in the channels of BCP-R than in those of BCP-S. Since the two CaP ceramics differed only in their surface architecture, the results hereby demonstrate that microporous CaP ceramics may induce ectopic osteogenesis through surface architecture. © 2014 Wiley Periodicals, Inc.

Expression variation in connected recombinant populations of Arabidopsis thaliana highlights distinct transcriptome architectures

Directory of Open Access Journals (Sweden)

Cubillos Francisco A

2012-03-01

Full Text Available Abstract Background Expression traits can vary quantitatively between individuals and have a complex inheritance. Identification of the genetics underlying transcript variation can help in the understanding of phenotypic variation due to genetic factors regulating transcript abundance and shed light into divergence patterns. So far, only a limited number of studies have addressed this subject in Arabidopsis, with contrasting results due to dissimilar statistical power. Here, we present the transcriptome architecture in leaf tissue of two RIL sets obtained from a connected-cross design involving 3 commonly used accessions. We also present the transcriptome architecture observed in developing seeds of a third independent cross. Results The utilisation of the novel R/eqtl package (which goal is to automatize and extend functions from the R/qtl package allowed us to map 4,290 and 6,534 eQTLs in the Cvi-0 × Col-0 and Bur-0 × Col-0 recombinant populations respectively. In agreement with previous studies, we observed a larger phenotypic variance explained by eQTLs in linkage with the controlled gene (potentially cis-acting, compared to distant loci (acting necessarily indirectly or in trans. Distant eQTLs hotspots were essentially not conserved between crosses, but instead, cross-specific. Accounting for confounding factors using a probabilistic approach (VBQTL increased the mapping resolution and the number of significant associations. Moreover, using local eQTLs obtained from this approach, we detected evidence for a directional allelic effect in genes with related function, where significantly more eQTLs than expected by chance were up-regulated from one of the accessions. Primary experimental data, analysis parameters, eQTL results and visualisation of LOD score curves presented here are stored and accessible through the QTLstore service database http://qtlstore.versailles.inra.fr/. Conclusions Our results demonstrate the extensive diversity and

PEMBELAJARAN BERBANTUAN MULTIMEDIA BERDASARKAN COGNITIVE LOAD THEORY PADA PELAJARAN MATEMATIKA SD

OpenAIRE

Rissa Prima Kurniawati

2016-01-01

Multimedia is media that combine two or more elements are composed of text, graphics, images, photographs, audio, video, and animation are integrated. In multimedia-assisted learning, students are given the opportunity to learn not only of learning resources such as teachers, but give the opportunity to students to develop better cognitive, creative, and innovative. Cognitive Load Theory is a theory that was introduced as a teaching theory based on the knowledge of human cognitive architectur...

Pembelajaran Berbantuan Multimedia Berdasarkan Cognitive Load Theory Pada Pelajaran Matematika SD

OpenAIRE

Kurniawati, Rissa Prima

2014-01-01

Multimedia is media that combine two or more elements are composed of text, graphics, images, photographs, audio, video, and animation are integrated. In multimedia-assisted learning, students are given the opportunity to learn not only of learning resources such as teachers, but give the opportunity to students to develop better cognitive, creative, and innovative. Cognitive Load Theory is a theory that was introduced as a teaching theory based on the knowledge of human cognitive architectur...

An Efficient FFT For OFDM Based Cognitive Radio On A Reconfigurable Architecture

NARCIS (Netherlands)

Zhang, Q.; Kokkeler, Andre B.J.; Smit, Gerardus Johannes Maria

2007-01-01

Cognitive Radio is a promising technology to utilize non-used parts of the spectrum that actually are assigned to licensed services. An adaptive OFDM based Cognitive Radio system has the capacity to nullify individual carriers to avoid interference to the licensed user. Therefore, there could be a

Enseigner dans un programme universitaire innovant : de nouveaux rôles à apprivoiser, des actes pédagogiques à diversifier

Directory of Open Access Journals (Sweden)

Nathalie Lefebvre

2012-09-01

Full Text Available Cette recherche vise à décrire, à partir d’observations empiriques, les rôles exercés et les actes pédagogiques effectués par les enseignantes et les enseignants engagés dans quatre programmes universitaires canadiens jugés innovants. L’observation directe en classe a permis de recueillir leurs propos qui ont été analysés à l’aide de deux grilles construites progressivement au cours de l’étude: la liste des dimensions théoriques et la grille des niveaux de centration sur l’apprentissage. Les résultats obtenus démontrent que les rôles et les actes pédagogiques observés apparaissent moins diversifiés et moins centrés sur l’apprentissage que ce qui est attendu dans un contexte novateur de formation.This research, based on empirical observations, describes the roles and teaching acts carried out by professors engaged in four innovative university programs in Canada. Classrooms observations were used to collect data, which were then analyzed using two grids built progressively during the study: a list of theoretical dimensions and a grid showing degrees of focus on learning. In terms of results, the roles and actions of the four university professors were found to be less diversified and less centered on student learning than was expected from their innovative instructional context.

The impact of subjective cognitive fatigue and depression on cognitive function in patients with multiple sclerosis.

Science.gov (United States)

Golan, Daniel; Doniger, Glen M; Wissemann, Karl; Zarif, Myassar; Bumstead, Barbara; Buhse, Marijean; Fafard, Lori; Lavi, Idit; Wilken, Jeffrey; Gudesblatt, Mark

2018-02-01

The association between subjective cognitive fatigue and objective cognitive dysfunction in patients with multiple sclerosis (PwMS) has been studied, with conflicting results. To explore the impact of fatigue on cognitive function, while controlling for the influence of depression, disability, comorbidities, and psychotropic medications. PwMS completed a computerized cognitive testing battery with age- and education-adjusted cognitive domain scores. Disability (Expanded Disability Status Scale (EDSS)), cognitive fatigue, and depression were concurrently evaluated. In all, 699 PwMS were included. Both cognitive fatigue and depression were significantly and negatively correlated with the same cognitive domains: information processing speed, executive function, attention, motor function, and memory (-0.15 ⩽ r ⩽ -0.14 for cognitive fatigue; -0.24 ⩽ r ⩽ -0.19 for depression). Multivariate analysis revealed significant but small independent correlations only between depression and neuropsychological test results, while cognitive fatigue had no independent correlation with objective cognitive function except for a trend toward impaired motor function in highly fatigued PwMS. Depression and cognitive fatigue accounted for no more than 6% of the variance in objective cognitive domain scores. Cognitive fatigue is not independently related to objective cognitive impairment. Depression may influence cognitive function of PwMS primarily when it is severe. Cognitive impairment in PwMS should not be ascribed to fatigue or mild depression.

Cockpit System Situational Awareness Modeling Tool

Science.gov (United States)

Keller, John; Lebiere, Christian; Shay, Rick; Latorella, Kara

2004-01-01

This project explored the possibility of predicting pilot situational awareness (SA) using human performance modeling techniques for the purpose of evaluating developing cockpit systems. The Improved Performance Research Integration Tool (IMPRINT) was combined with the Adaptive Control of Thought-Rational (ACT-R) cognitive modeling architecture to produce a tool that can model both the discrete tasks of pilots and the cognitive processes associated with SA. The techniques for using this tool to predict SA were demonstrated using the newly developed Aviation Weather Information (AWIN) system. By providing an SA prediction tool to cockpit system designers, cockpit concepts can be assessed early in the design process while providing a cost-effective complement to the traditional pilot-in-the-loop experiments and data collection techniques.

Research in Architectural Education: Theory and Practice of Visual Training

Directory of Open Access Journals (Sweden)

Kristin Jones

2016-12-01

Full Text Available Today, the significance of vision is often considered from multiple points of view including perceptual, cognitive, imaginative, historical, technical, ethical, cultural, and critical perspectives.  Visual Studies, Visual Communication and Visual Design are popular courses of study.  This paper brings to light a course in architectural education called Visual Training which aims to sharpen visual perception and enhance aesthetic judgment. The paper articulates the pedagogy of Visual Training linking the 78-year old practice with educational theory.  It describes the course structure, the conduct of the exercises and interpretation of course outcomes to inform teaching practice.  The discussion shows how Visual Training addresses enduring pedagogical concerns and establishes the grounds for architectural critique. The paper raises awareness of the role of vision in architectural education and brings attention to a program for developing the eye which acknowledges a connection between the sensory and the intellectual realms.  Looking at the grounds and potential of Visual Training in architectural education raises important questions about pedagogy in architecture that may stimulate further discussion and cause a rethinking of not only the importance of training the eye, but also the significance of the methods we use.

ATCA for Machines-- Advanced Telecommunications Computing Architecture

Energy Technology Data Exchange (ETDEWEB)

Larsen, R.S.; /SLAC

2008-04-22

The Advanced Telecommunications Computing Architecture is a new industry open standard for electronics instrument modules and shelves being evaluated for the International Linear Collider (ILC). It is the first industrial standard designed for High Availability (HA). ILC availability simulations have shown clearly that the capabilities of ATCA are needed in order to achieve acceptable integrated luminosity. The ATCA architecture looks attractive for beam instruments and detector applications as well. This paper provides an overview of ongoing R&D including application of HA principles to power electronics systems.

Awareness and Perception of Housewives in Selected Municipalities of Palawan Regarding R.A. 9262 (Anti-Violence against Women and their Children Act of 2004

Directory of Open Access Journals (Sweden)

Dr. Cecilia S. Santiago

2014-10-01

Full Text Available This study was conducted to determine the level of awareness and perception of housewives in selected municipalities of Palawan regarding R.A. 9262. Specifically, it aimed to determine the demographic characteristics of the respondents; to identify the level of awareness of housewives regarding R.A. 9262; and to find out their perception regarding the Act. Seven municipalities which include Aborlan, Narra, Brooke’s Point, Quezon, Rizal, Bataraza and El Nido were the study sites. One hundred women from each municipality were purposely selected that served as respondents with a total of 700. Those considered were married, with husband at present and who has children. The survey questionnaire which was translated in Filipino was composed of two parts. Part one was about the demographic characteristics of the respondents while part two dealt on statements about acts of violence against women & their children as stated in RA 9262 that determined the level of awareness & perception on the provisions of the said Republic Act. Results revealed that the mean age of the respondents was 38.39 years old and the mean number of children was 3.63. In addition, most of the respondents were plain housewives has 3-4 children, high school graduates and within the PhP 5,000.00 and below bracket of monthly income. With regards to the level of awareness, majority of the respondents were moderately aware of the provisions of R.A. 9262. As to the perception of the respondents, they strongly agree that the provisions or statements are considered acts of violence against women and their children. Based on the results of the study, an Action Plan will be proposed which will focus on the enhancement of the housewives’ awareness regarding R.A. 9262 to provide information and make them fully aware of the provisions of the republic act and be safe from domestic violence.

The Cognitive Architecture for Chaining of Two Mental Operations

Science.gov (United States)

Sackur, Jerome; Dehaene, Stanislas

2009-01-01

A simple view, which dates back to Turing, proposes that complex cognitive operations are composed of serially arranged elementary operations, each passing intermediate results to the next. However, whether and how such serial processing is achieved with a brain composed of massively parallel processors, remains an open question. Here, we study…

Categorial Compositionality: A Category Theory Explanation for the Systematicity of Human Cognition

OpenAIRE

Phillips, Steven; Wilson, William H.

2010-01-01

Classical and Connectionist theories of cognitive architecture seek to explain systematicity (i.e., the property of human cognition whereby cognitive capacity comes in groups of related behaviours) as a consequence of syntactically and functionally compositional representations, respectively. However, both theories depend on ad hoc assumptions to exclude specific instances of these forms of compositionality (e.g. grammars, networks) that do not account for systematicity. By analogy with the P...

PEMBELAJARAN BERBANTUAN MULTIMEDIA BERDASARKAN COGNITIVE LOAD THEORY PADA PELAJARAN MATEMATIKA SD

Directory of Open Access Journals (Sweden)

Rissa Prima Kurniawati

2016-11-01

Full Text Available Multimedia is media that combine two or more elements are composed of text, graphics, images, photographs, audio, video, and animation are integrated. In multimedia-assisted learning, students are given the opportunity to learn not only of learning resources such as teachers, but give the opportunity to students to develop better cognitive, creative, and innovative. Cognitive Load Theory is a theory that was introduced as a teaching theory based on the knowledge of human cognitive architecture that we have. The main principle of Cognitive Load Theory is the quality of learning is enhanced if attention is concentrated on the role and limitations of working memory. Three cognitive load in working memory, which is intrinsic cognitive load, Germany cognitive load, and extraneous cognitive load.   Keywords: Multimedia, Cognitive Load Theory, intrinsic cognitive load, Germany cognitive load, and extraneous cognitive load.

The Present of Architectural Psychology Researches in China- Based on the Bibliometric Analysis and Knowledge Mapping

Science.gov (United States)

Zhu, LeiYe; Wang, Qi; Xu, JunHua; Wu, Qing; Jin, MeiDong; Liao, RongJun; Wang, HaiBin

2018-03-01

Architectural Psychology is an interdisciplinary subject of psychology and architecture that focuses on architectural design by using Gestalt psychology, cognitive psychology and other related psychology principles. Researchers from China have achieved fruitful achievements in the field of architectural psychology during past thirty-three years. To reveal the current situation of the field in China, 129 related papers from the China National Knowledge Infrastructure (CNKI) were analyzed by CiteSpace II software. The results show that: (1) the studies of the field in China have been started since 1984 and the annual number of the papers increased dramatically from 2008 and reached a historical peak in 2016. Shanxi Architecture tops the list of contributing publishing journals; Wuhan University, Southwest Jiaotong University and Chongqing University are the best performer among the contributing organizations. (2) “Environmental Psychology”, “Architectural Design” and “Architectural Psychology” are the most frequency keywords. The frontiers of the field in China are “architectural creation” and “environmental psychology” while the popular research topics were“residential environment”, “spatial environment”, “environmental psychology”, “architectural theory” and “architectural psychology”.

The Everyday Cognition Scale in Parkinson's disease

OpenAIRE

Cooper, Rachel A.; Benge, Jared; Lantrip, Crystal; Soileau, Michael J.

2017-01-01

This brief report describes caregiver ratings on the Everyday Cognition (ECog) scale, a psychometrically robust measure of cognitively driven daily activities that was initially designed for other neurodegenerative conditions, in individuals with Parkinson's disease (PD). In 49 individuals with PD, those with suspected PD dementia had more difficulties across ECog domains than those with normal cognition or mild cognitive impairment. Results from multiple regression analyses revealed that act...

Design of a Production System for Cognitive Modeling #1. Technical Report 77-2.

Science.gov (United States)

Anderson, John R.; Kline, Paul J.

This report describes several of the design decisions underlying ACT, a production system model of human cognition. ACT can be considered a high level computer programming language as well as a theory of the cognitive mechanisms underlying human information processing. ACT design decisions were based on both psychological and artificial…

Addenbrooke’s Cognitive Examination and Individual Domain Cut-Off Scores for Discriminating between Different Cognitive Subtypes of Parkinson’s Disease

OpenAIRE

Dagmar Berankova; Eva Janousova; Martina Mrackova; Ilona Eliasova; Milena Kostalova; Svetlana Skutilova; Irena Rektorova

2015-01-01

Objective. The main aim of this study was to verify the sensitivity and specificity of Addenbrooke's Cognitive Examination-Revised (ACE-R) in discriminating between Parkinson's disease (PD) with normal cognition (PD-NC) and PD with mild cognitive impairment (PD-MCI) and between PD-MCI and PD with dementia (PD-D). We also evaluated how ACE-R correlates with neuropsychological cognitive tests in PD. Methods. We examined three age-matched groups of PD patients diagnosed according to the Movement...

Cultural schema and design activity in an architectural design studio

Directory of Open Access Journals (Sweden)

Gökçe Ketizmen Önal

2017-06-01

Full Text Available Research on the cognitive activities and on the structure and quality of knowledge flow involved in architectural design education is increasing. These studies generally focus on the interaction between student and instructor, including processes such as producing ideas, solving display problems, and integrating design strategies. These studies commonly include computational evaluations and confirmation of the coding of knowledge. They may also include the determination of designer׳s thoughts and cognitive actions of design process, as well as the analysis and digitization of verbal protocols during the design process. In most of these studies, the designer׳s cultural and psychological components are not considered. Accordingly, research on the effects of designers’ cultural schema on design activity in design studios is limited. This study aimed to solve this problem by analyzing the relationship between design activity and the designer׳s cultural schema in a design studio. We performed an experimental study based on a specific conceptual framework and a research model aimed at identifying the relationships among cultural schemas, the architectural design process, and design studios.

Social Intelligence for a Robot Engaging People in Cognitive Training Activities

Directory of Open Access Journals (Sweden)

Jeanie Chan

2012-10-01

Full Text Available Current research supports the use of cognitive training interventions to improve the brain functioning of both adults and children. Our work focuses on exploring the potential use of robot assistants to allow for these interventions to become more accessible. Namely, we aim to develop an intelligent, socially assistive robot that can engage individuals in person-centred cognitively stimulating activities. In this paper, we present the design of a novel control architecture for the robot Brian 2.0, which enables the robot to be a social motivator by providing assistance, encouragement and celebration during an activity. A hierarchical reinforcement learning approach is used in the architecture to allow the robot to: 1 learn appropriate assistive behaviours based on the structure of the activity, and 2 personalize an interaction based on user states. Experiments show that the control architecture is effective in determining the robot's optimal assistive behaviours during a memory game interaction.

Hypnose, sommeil, placebo ? : Les réponses de la Théorie neuronale de la Cognition – Tome 2

OpenAIRE

Touzet , Claude

2014-01-01

International audience; Initialement uniquement dédié aux quelques « faits » comme :l'hypnose, le plaisir, le sommeil et les rêves, la responsabilité, l'effet placebo et la schizophréniequi n'avaient pas reçu d'explications de la part de la Théorie neuronale de la Cognition (tome 1 – Conscience, intelligence, libre-arbitre), ce second opus a rapidement dévié de sa mission originale pour intégrer des aspects encore plus controversés, comme :- le paranormal,- l'influence de l'intention sur la r...

Cognitive and functional neuroimaging correlate for anosognosia in mild cognitive impairment and Alzheimer's disease

DEFF Research Database (Denmark)

Vogel, Asmus; Hasselbalch, Steen G; Gade, Anders

2005-01-01

To investigate the correlation between anosognosia and behavioural symptoms, performance on executive tests, and frontal cortex regional cerebral blood flow (rCBF) in patients with 'amnestic mild cognitive impairment' (MCI) and mild Alzheimer's disease (AD).......To investigate the correlation between anosognosia and behavioural symptoms, performance on executive tests, and frontal cortex regional cerebral blood flow (rCBF) in patients with 'amnestic mild cognitive impairment' (MCI) and mild Alzheimer's disease (AD)....

The Addenbrooke's Cognitive Examination-Revised accurately detects cognitive decline in Huntington's disease.

Science.gov (United States)

Begeti, Faye; Tan, Adrian Y K; Cummins, Gemma A; Collins, Lucy M; Guzman, Natalie Valle; Mason, Sarah L; Barker, Roger A

2013-11-01

Cognitive features, which begin before manifestation of the motor features, are an integral part of Huntington's disease and profoundly affect quality of life. A number of neuropsychological batteries have been used to assess this aspect of the condition, many of which are difficult to administer and time consuming, especially in advanced disease. We, therefore, investigated a simple and practical way to monitor cognition using the Addenbrooke's Cognitive Examination-Revised (ACE-R) in 126 manifest Huntington's disease patients, 28 premanifest gene carriers and 21 controls. Using this test, we demonstrated a selective decrease in phonemic, but not semantic, fluency in premanifest participants Cognitive decline in manifest Huntington's disease varied according to disease severity with extensive cognitive decline observed in early-stage Huntington's disease patients, indicating that this would be an optimal stage for interventions designed to halt cognitive decline, and lesser changes in the advanced cases. We next examined cognitive performance in patients prescribed antidopaminergic drugs as these drugs are known to decrease cognition when administered to healthy volunteers. We paradoxically found that these drugs may be beneficial, as early-stage Huntington's disease participants in receipt of them had improved attention and Mini-Mental State Examination scores. In conclusion, this is the first study to test the usefulness of the ACE-R in a Huntington's disease population and demonstrates that this is a brief, inexpensive and practical way to measure global cognitive performance in clinical practice with potential use in clinical trials.

Mirror Neurons, Embodied Cognitive Agents and Imitation Learning

OpenAIRE

Wiedermann, Jiří

2003-01-01

Mirror neurons are a relatively recent discovery; it has been conjectured that these neurons play an important role in imitation learning and other cognitive phenomena. We will study a possible place and role of mirror neurons in the neural architecture of embodied cognitive agents. We will formulate and investigate the hypothesis that mirror neurons serve as a mechanism which coordinates the multimodal (i.e., motor, perceptional and proprioceptive) information and completes it so that the ag...

Categorial compositionality: a category theory explanation for the systematicity of human cognition.

Directory of Open Access Journals (Sweden)

Steven Phillips

Full Text Available Classical and Connectionist theories of cognitive architecture seek to explain systematicity (i.e., the property of human cognition whereby cognitive capacity comes in groups of related behaviours as a consequence of syntactically and functionally compositional representations, respectively. However, both theories depend on ad hoc assumptions to exclude specific instances of these forms of compositionality (e.g. grammars, networks that do not account for systematicity. By analogy with the Ptolemaic (i.e. geocentric theory of planetary motion, although either theory can be made to be consistent with the data, both nonetheless fail to fully explain it. Category theory, a branch of mathematics, provides an alternative explanation based on the formal concept of adjunction, which relates a pair of structure-preserving maps, called functors. A functor generalizes the notion of a map between representational states to include a map between state transformations (or processes. In a formal sense, systematicity is a necessary consequence of a higher-order theory of cognitive architecture, in contrast to the first-order theories derived from Classicism or Connectionism. Category theory offers a re-conceptualization for cognitive science, analogous to the one that Copernicus provided for astronomy, where representational states are no longer the center of the cognitive universe--replaced by the relationships between the maps that transform them.

Categorial compositionality: a category theory explanation for the systematicity of human cognition.

Science.gov (United States)

Phillips, Steven; Wilson, William H

2010-07-22

Classical and Connectionist theories of cognitive architecture seek to explain systematicity (i.e., the property of human cognition whereby cognitive capacity comes in groups of related behaviours) as a consequence of syntactically and functionally compositional representations, respectively. However, both theories depend on ad hoc assumptions to exclude specific instances of these forms of compositionality (e.g. grammars, networks) that do not account for systematicity. By analogy with the Ptolemaic (i.e. geocentric) theory of planetary motion, although either theory can be made to be consistent with the data, both nonetheless fail to fully explain it. Category theory, a branch of mathematics, provides an alternative explanation based on the formal concept of adjunction, which relates a pair of structure-preserving maps, called functors. A functor generalizes the notion of a map between representational states to include a map between state transformations (or processes). In a formal sense, systematicity is a necessary consequence of a higher-order theory of cognitive architecture, in contrast to the first-order theories derived from Classicism or Connectionism. Category theory offers a re-conceptualization for cognitive science, analogous to the one that Copernicus provided for astronomy, where representational states are no longer the center of the cognitive universe--replaced by the relationships between the maps that transform them.

ATCA for Machines-- Advanced Telecommunications Computing Architecture

International Nuclear Information System (INIS)

Larsen, R

2008-01-01

The Advanced Telecommunications Computing Architecture is a new industry open standard for electronics instrument modules and shelves being evaluated for the International Linear Collider (ILC). It is the first industrial standard designed for High Availability (HA). ILC availability simulations have shown clearly that the capabilities of ATCA are needed in order to achieve acceptable integrated luminosity. The ATCA architecture looks attractive for beam instruments and detector applications as well. This paper provides an overview of ongoing R and D including application of HA principles to power electronics systems

Cognitive radio application for vehicular ad hoc networks (VANETS

Directory of Open Access Journals (Sweden)

Miladić Suzana D.

2016-01-01

Full Text Available This paper presents the application of cognitive radio technology in vehicular ad-hoc networks aimed to improve the communications between vehicles themselves as well as between vehicles and roadside infrastructure. Due to dynamic approach of spectrum access, cognitive radio is a technology that enables more efficient usage of radio-frequency spectrum. We review actual approaches and discuss research challenges related to the use of cognitive radio technology in vehicular ad hoc networks with emphasis on architecture, spectrum management as well as QoS optimization. The researching on cognitive radio application in vehicular networks is still developing and there are not many experimental platforms due to their complex setups. Some related research projects and cognitive radio realizations are provided in this paper.

Assured Mission Support Space Architecture (AMSSA) study

Science.gov (United States)

Hamon, Rob

1993-01-01

The assured mission support space architecture (AMSSA) study was conducted with the overall goal of developing a long-term requirements-driven integrated space architecture to provide responsive and sustained space support to the combatant commands. Although derivation of an architecture was the focus of the study, there are three significant products from the effort. The first is a philosophy that defines the necessary attributes for the development and operation of space systems to ensure an integrated, interoperable architecture that, by design, provides a high degree of combat utility. The second is the architecture itself; based on an interoperable system-of-systems strategy, it reflects a long-range goal for space that will evolve as user requirements adapt to a changing world environment. The third product is the framework of a process that, when fully developed, will provide essential information to key decision makers for space systems acquisition in order to achieve the AMSSA goal. It is a categorical imperative that military space planners develop space systems that will act as true force multipliers. AMSSA provides the philosophy, process, and architecture that, when integrated with the DOD requirements and acquisition procedures, can yield an assured mission support capability from space to the combatant commanders. An important feature of the AMSSA initiative is the participation by every organization that has a role or interest in space systems development and operation. With continued community involvement, the concept of the AMSSA will become a reality. In summary, AMSSA offers a better way to think about space (philosophy) that can lead to the effective utilization of limited resources (process) with an infrastructure designed to meet the future space needs (architecture) of our combat forces.

The Portuguese version of Addenbrooke's Cognitive Examination-Revised (ACE-R) in the diagnosis of subcortical vascular dementia and Alzheimer's disease.

Science.gov (United States)

Gonçalves, Cátia; Pinho, Maria Salomé; Cruz, Vitor; Pais, Joana; Gens, Helena; Oliveira, Fátima; Santana, Isabel; Rente, José; Santos, José Manuel

2015-01-01

The aim of this study was to investigate the accuracy of the Portuguese version of Addenbrooke's Cognitive Examination-Revised (ACE-R) in detecting and differentiating early stage subcortical vascular dementia (SVD) from early stage Alzheimer's disease (AD). Ninety-two subjects (18 SVD patients, 36 AD patients, and 38 healthy controls) were assessed using the ACE-R. Between-group's differences were evaluated using the Quade's rank analysis of covariance. The diagnostic accuracy and discriminatory ability of the ACE-R were examined via receiver operating characteristic (ROC) analysis. The ACE-R was able to successfully discriminate between patients and healthy subjects. The mean ACE-R total scores differed between SVD and AD patients; there were also significant differences in attention and orientation and in memory measures between the groups. An optimal cut-off of 72/73 was found for the detection of AD (sensitivity: 97%; specificity: 92%) and SVD (sensitivity: 100%; specificity: 92%).

CogWnet: A Resource Management Architecture for Cognitive Wireless Networks

KAUST Repository

Alqerm, Ismail; Shihada, Basem; Shin, Kang G.

2013-01-01

With the increasing adoption of wireless communication technologies, there is a need to improve management of existing radio resources. Cognitive radio is a promising technology to improve the utilization of wireless spectrum. Its operating

Diagnostic utility of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) and its combination with the Addenbrooke's Cognitive Examination-Revised (ACE-R) in a memory clinic-based population.

Science.gov (United States)

Hancock, P; Larner, A J

2009-06-01

The study aimed to assess the clinical utility of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) in patients referred to memory clinics, alone and in combination with the Addenbrooke's Cognitive Examination-Revised (ACE-R) and the Mini-mental State Examination (MMSE). This pragmatic prospective study was based on consecutive referrals attending with an informant (n = 144) to two memory clinics over a 12-month period. Patients were diagnosed using standard clinical diagnostic criteria for dementia (DSM-IV) as gold standard (dementia prevalence = 59%). The IQCODE was administered to informants, and the ACE-R and/or MMSE to most patients. The IQCODE proved acceptable to informants, and was quick and easy to use. Using traditional parameters of diagnostic utility (sensitivity, specificity, positive predictive value, likelihood ratios), the performance of the IQCODE at optimal test accuracy was highly sensitive (0.86) for the diagnosis of dementia but specificity was poor (0.39) with suboptimal positive predictive value (0.67) and small or unimportant likelihood ratios. Overall diagnostic accuracy based on area under the receiver operating characteristic (ROC) curve was 0.71. Combining the IQCODE with either ACE-R or MMSE greatly improved accuracy, specificity and positive predictive value when the tests were used in series, but not when used in parallel. In a memory clinic based population, the IQCODE proved sensitive for the diagnosis of dementia but overall diagnostic accuracy was suboptimal. Combining the IQCODE in series with the ACE-R or MMSE greatly improved diagnostic utility.

PIN architecture for ultrasensitive organic thin film photoconductors.

Science.gov (United States)

Jin, Zhiwen; Wang, Jizheng

2014-06-17

Organic thin film photoconductors (OTFPs) are expected to have wide applications in the field of optical communications, artificial vision and biomedical sensing due to their great advantages of high flexibility and low-cost large-area fabrication. However, their performances are not satisfactory at present: the value of responsivity (R), the parameter that measures the sensitivity of a photoconductor to light, is below 1 AW(-1). We believe such poor performance is resulted from an intrinsic self-limited effect of present bare blend based device structure. Here we designed a PIN architecture for OTFPs, the PIN device exhibits a significantly improved high R value of 96.5 AW(-1). The PIN architecture and the performance the PIN device shows here should represent an important step in the development of OTFPs.

Enhancer-derived lncRNAs regulate genome architecture: fact or fiction?

CSIR Research Space (South Africa)

Fanucchi, Stephanie

2017-06-01

Full Text Available How does the non-coding portion of the genome contribute to the regulation of genome architecture? A recent paper by Tan et al. focuses on the relationship between cis-acting complex-trait-associated lincRNAs and the formation of chromosomal...

Fluid and flexible minds: Intelligence reflects synchrony in the brain’s intrinsic network architecture

Directory of Open Access Journals (Sweden)

Michael A. Ferguson

2017-06-01

Full Text Available Human intelligence has been conceptualized as a complex system of dissociable cognitive processes, yet studies investigating the neural basis of intelligence have typically emphasized the contributions of discrete brain regions or, more recently, of specific networks of functionally connected regions. Here we take a broader, systems perspective in order to investigate whether intelligence is an emergent property of synchrony within the brain’s intrinsic network architecture. Using a large sample of resting-state fMRI and cognitive data (n = 830, we report that the synchrony of functional interactions within and across distributed brain networks reliably predicts fluid and flexible intellectual functioning. By adopting a whole-brain, systems-level approach, we were able to reliably predict individual differences in human intelligence by characterizing features of the brain’s intrinsic network architecture. These findings hold promise for the eventual development of neural markers to predict changes in intellectual function that are associated with neurodevelopment, normal aging, and brain disease. In our study, we aimed to understand how individual differences in intellectual functioning are reflected in the intrinsic network architecture of the human brain. We applied statistical methods, known as spectral decompositions, in order to identify individual differences in the synchronous patterns of spontaneous brain activity that reliably predict core aspects of human intelligence. The synchrony of brain activity at rest across multiple discrete neural networks demonstrated positive relationships with fluid intelligence. In contrast, global synchrony within the brain’s network architecture reliably, and inversely, predicted mental flexibility, a core facet of intellectual functioning. The multinetwork systems approach described here represents a methodological and conceptual extension of earlier efforts that related differences in

Socio-economic position early in life, cognitive development and cognitive change from young adulthood to middle age

DEFF Research Database (Denmark)

Osler, Merete; Avlund, Kirsten; Mortensen, Erik Lykke

2013-01-01

BACKGROUND: We examine the influence of social circumstances early in life on changes in cognitive function from young adulthood to middle age, and we explore the impact of birth characteristics, childhood activities, education and adult social class on the expected relationship. METHODS: A cohort...... of 11 532 men born in Copenhagen, Denmark in 1953-7906, 10 246 and 2483 participants-had completed assessments of cognitive function at ages 12, 18 and 57 years, respectively. Linear regression was used to investigate the association of early-life characteristics with cognitive test scores at these ages...... and with score changes from early to mid-adulthood. RESULTS: The cognitive scores at age 57 years had high correlations with scores at ages 12 (r = 0.67) and 18 years (r = 0.70), and these two scores also showed bivariate correlation (r = 0.69). Having a father from the working class at birth was associated...

Gait and Cognition in Parkinson’s Disease: Cognitive Impairment Is Inadequately Reflected by Gait Performance during Dual Task

Directory of Open Access Journals (Sweden)

Heiko Gaßner

2017-10-01

Full Text Available IntroductionCognitive and gait deficits are common symptoms in Parkinson’s disease (PD. Motor-cognitive dual tasks (DTs are used to explore the interplay between gait and cognition. However, it is unclear if DT gait performance is indicative for cognitive impairment. Therefore, the aim of this study was to investigate if cognitive deficits are reflected by DT costs of spatiotemporal gait parameters.MethodsCognitive function, single task (ST and DT gait performance were investigated in 67 PD patients. Cognition was assessed by the Montreal Cognitive Assessment (MoCA followed by a standardized, sensor-based gait test and the identical gait test while subtracting serial 3’s. Cognitive impairment was defined by a MoCA score <26. DT costs in gait parameters [(DT − ST/ST × 100] were calculated as a measure of DT effect on gait. Correlation analysis was used to evaluate the association between MoCA performance and gait parameters. In a linear regression model, DT gait costs and clinical confounders (age, gender, disease duration, motor impairment, medication, and depression were correlated to cognitive performance. In a subgroup analysis, we compared matched groups of cognitively impaired and unimpaired PD patients regarding differences in ST, DT, and DT gait costs.ResultsCorrelation analysis revealed weak correlations between MoCA score and DT costs of gait parameters (r/rSp ≤ 0.3. DT costs of stride length, swing time variability, and maximum toe clearance (|r/rSp| > 0.2 were included in a regression analysis. The parameters only explain 8% of the cognitive variance. In combination with clinical confounders, regression analysis showed that these gait parameters explained 30% of MoCA performance. Group comparison revealed strong DT effects within both groups (large effect sizes, but significant between-group effects in DT gait costs were not observed.ConclusionThese findings suggest that DT gait performance is not indicative

Relationships among gender, cognitive style, academic major, and performance on the Piaget water-level task.

Science.gov (United States)

Hammer, R E; Hoffer, N; King, W L

1995-06-01

Many researchers have found that more college-age adults than would be expected fail Piaget's water-level task, with women failing more frequently than men. It has been hypothesized that differences in cognitive style may account for performance differences on the water-level task. In the present study, 27 male and 27 female architectural students and 27 male and 27 female liberal-arts students were assessed for their performance on both Piaget's Water-level Task and Witkin's Group Embedded Figures Test. No difference was found in performance of male and female architectural students on either task, but male liberal-arts students scored significantly higher than female liberal-arts students on both measures. A disembedding cognitive style predicted success on the water-level task for the architectural students but not for the liberal arts students.

Space and place concepts analysis based on semiology approach in residential architecture

Directory of Open Access Journals (Sweden)

Mojtaba Parsaee

2015-12-01

Full Text Available Space and place are among the fundamental concepts in architecture about which many discussions have been held and the complexity and importance of these concepts were focused on. This research has introduced an approach to better cognition of the architectural concepts based on theory and method of semiology in linguistics. Hence, at first the research investigates the concepts of space and place and explains their characteristics in architecture. Then, it reviews the semiology theory and explores its concepts and ideas. After obtaining the principles of theory and also the method of semiology, they are redefined in an architectural system based on an adaptive method. Finally, the research offers a conceptual model which is called the semiology approach by considering the architectural system as a system of signs. The approach can be used to decode the content of meanings and forms and analyses of the architectural mechanism in order to obtain its meanings and concepts. In this way and based on this approach, the residential architecture of the traditional city of Bushehr – Iran was analyzed as a case of study and its concepts were extracted. The results of this research demonstrate the effectiveness of this approach in structure detection and identification of an architectural system. Besides, this approach has the capability to be used in processes of sustainable development and also be a basis for deconstruction of architectural texts. The research methods of this study are qualitative based on comparative and descriptive analyses.

Computational representation of Alzheimer's disease evolution applied to a cooking activity.

Science.gov (United States)

Serna, Audrey; Rialle, Vincent; Pigot, Hélène

2006-01-01

This article presents a computational model and a simulation of the decrease of activities of daily living performances due to Alzheimer's disease. The disease evolution is simulated thanks to the cognitive architecture ACT-R. Activities are represented according to the retrieval of semantic units in declarative memory and the trigger of rules in procedural memory. The simulation of Alzheimer's disease decrease is simulated thanks to the variation of subsymbolic parameters. The model is applied to a cooking activity. Simulation of 100 hundred subjects shows results similar to those realised in a standardized assessment with human subjects.

Distinct effects of IPSU and suvorexant on mouse sleep architecture

Directory of Open Access Journals (Sweden)

Daniel eHoyer

2013-12-01

Full Text Available Dual orexin receptor (OXR antagonists (DORAs such as almorexant, SB-649868, suvorexant (MK-4305 and filorexant (MK-6096, have shown promise for the treatment of insomnias and sleep disorders. Whether antagonism of both OX1R and OX2R is necessary for sleep induction has been a matter of some debate. Experiments using knockout mice suggest that it may be sufficient to antagonize only OX2R. The recent identification of an orally bioavailable, brain penetrant OX2R preferring antagonist 2-((1H-Indol-3-ylmethyl-9-(4-methoxypyrimidin-2-yl-2,9-diazaspiro[5.5]undecan-1-one (IPSU has allowed us to test whether selective antagonism of OX2R may also be a viable strategy for induction of sleep. We previously demonstrated that IPSU and suvorexant increase sleep when dosed during the mouse active phase (lights off; IPSU inducing sleep primarily by increasing NREM sleep, suvorexant primarily by increasing REM sleep. Here, our goal was to determine whether suvorexant and IPSU affect sleep architecture independently of overall sleep induction. We therefore tested suvorexant (25 mg/kg and IPSU (50 mg/kg in mice during the inactive phase (lights on when sleep is naturally more prevalent and when orexin levels are normally low. Whereas IPSU was devoid of effects on the time spent in NREM or REM, suvorexant substantially disturbed the sleep architecture by selectively increasing REM during the first 4 hours after dosing. At the doses tested, suvorexant significantly decreased wake only during the first hour and IPSU did not affect wake time. These data suggest that OX2R preferring antagonists may have a reduced tendency for perturbing NREM/REM architecture in comparison with DORAs. Whether this effect will prove to be a general feature of OX2R antagonists versus DORAs remains to be seen.

Sandwich-Architectured Poly(lactic acid)-Graphene Composite Food Packaging Films.

Science.gov (United States)

Goh, Kunli; Heising, Jenneke K; Yuan, Yang; Karahan, Huseyin E; Wei, Li; Zhai, Shengli; Koh, Jia-Xuan; Htin, Nanda M; Zhang, Feimo; Wang, Rong; Fane, Anthony G; Dekker, Matthijs; Dehghani, Fariba; Chen, Yuan

2016-04-20

Biodegradable food packaging promises a more sustainable future. Among the many different biopolymers used, poly(lactic acid) (PLA) possesses the good mechanical property and cost-effectiveness necessary of a biodegradable food packaging. However, PLA food packaging suffers from poor water vapor and oxygen barrier properties compared to many petroleum-derived ones. A key challenge is, therefore, to simultaneously enhance both the water vapor and oxygen barrier properties of the PLA food packaging. To address this issue, we design a sandwich-architectured PLA-graphene composite film, which utilizes an impermeable reduced graphene oxide (rGO) as the core barrier and commercial PLA films as the outer protective encapsulation. The synergy between the barrier and the protective encapsulation results in a significant 87.6% reduction in the water vapor permeability. At the same time, the oxygen permeability is reduced by two orders of magnitude when evaluated under both dry and humid conditions. The excellent barrier properties can be attributed to the compact lamellar microstructure and the hydrophobicity of the rGO core barrier. Mechanistic analysis shows that the large rGO lateral dimension and the small interlayer spacing between the rGO sheets have created an extensive and tortuous diffusion pathway, which is up to 1450-times the thickness of the rGO barrier. In addition, the sandwiched architecture has imbued the PLA-rGO composite film with good processability, which increases the manageability of the film and its competency to be tailored. Simulations using the PLA-rGO composite food packaging film for edible oil and potato chips also exhibit at least eight-fold extension in the shelf life of these oxygen and moisture sensitive food products. Overall, these qualities have demonstrated the high potential of a sandwich-architectured PLA-graphene composite film for food packaging applications.

Architecture for autonomy

Science.gov (United States)

Broten, Gregory S.; Monckton, Simon P.; Collier, Jack; Giesbrecht, Jared

2006-05-01

In 2002 Defence R&D Canada changed research direction from pure tele-operated land vehicles to general autonomy for land, air, and sea craft. The unique constraints of the military environment coupled with the complexity of autonomous systems drove DRDC to carefully plan a research and development infrastructure that would provide state of the art tools without restricting research scope. DRDC's long term objectives for its autonomy program address disparate unmanned ground vehicle (UGV), unattended ground sensor (UGS), air (UAV), and subsea and surface (UUV and USV) vehicles operating together with minimal human oversight. Individually, these systems will range in complexity from simple reconnaissance mini-UAVs streaming video to sophisticated autonomous combat UGVs exploiting embedded and remote sensing. Together, these systems can provide low risk, long endurance, battlefield services assuming they can communicate and cooperate with manned and unmanned systems. A key enabling technology for this new research is a software architecture capable of meeting both DRDC's current and future requirements. DRDC built upon recent advances in the computing science field while developing its software architecture know as the Architecture for Autonomy (AFA). Although a well established practice in computing science, frameworks have only recently entered common use by unmanned vehicles. For industry and government, the complexity, cost, and time to re-implement stable systems often exceeds the perceived benefits of adopting a modern software infrastructure. Thus, most persevere with legacy software, adapting and modifying software when and wherever possible or necessary -- adopting strategic software frameworks only when no justifiable legacy exists. Conversely, academic programs with short one or two year projects frequently exploit strategic software frameworks but with little enduring impact. The open-source movement radically changes this picture. Academic frameworks

Architectural slicing

DEFF Research Database (Denmark)

Christensen, Henrik Bærbak; Hansen, Klaus Marius

2013-01-01

Architectural prototyping is a widely used practice, con- cerned with taking architectural decisions through experiments with light- weight implementations. However, many architectural decisions are only taken when systems are already (partially) implemented. This is prob- lematic in the context...... of architectural prototyping since experiments with full systems are complex and expensive and thus architectural learn- ing is hindered. In this paper, we propose a novel technique for harvest- ing architectural prototypes from existing systems, \\architectural slic- ing", based on dynamic program slicing. Given...... a system and a slicing criterion, architectural slicing produces an architectural prototype that contain the elements in the architecture that are dependent on the ele- ments in the slicing criterion. Furthermore, we present an initial design and implementation of an architectural slicer for Java....

Context, Not Conflict, Drives Cognitive Control

Science.gov (United States)

Schlaghecken, Friederike; Martini, Paolo

2012-01-01

Theories of cognitive control generally assume that perceived conflict acts as a signal to engage inhibitory mechanisms that suppress subsequent conflicting information. Crucially, an absence of conflict is not regarded as being a relevant signal for cognitive control. Using a cueing, a priming, and a Simon task, we provide evidence that conflict…

Conflict detection and resolution system architecture for unmanned aerial vehicles in civil airspace

NARCIS (Netherlands)

Jenie, Y.I.; van Kampen, E.J.; Ellerbroek, J.; Hoekstra, J.M.

2015-01-01

A novel architecture for a general Unmanned Aerial Vehicle (UAV) Conflict Detection and Resolution (CD&R) system, in the context of their integration into the civilian airspace, is proposed in this paper. The architecture consists of layers of safety approaches ,each representing a combination of

SUSTAINABLE ARCHITECTURE : WHAT ARCHITECTURE STUDENTS THINK

OpenAIRE

SATWIKO, PRASASTO

2013-01-01

Sustainable architecture has become a hot issue lately as the impacts of climate change become more intense. Architecture educations have responded by integrating knowledge of sustainable design in their curriculum. However, in the real life, new buildings keep coming with designs that completely ignore sustainable principles. This paper discusses the results of two national competitions on sustainable architecture targeted for architecture students (conducted in 2012 and 2013). The results a...

Distributed Cognition (DCOG): Foundations for a Computational Associative Memory Model

National Research Council Canada - National Science Library

Eggleston, Robert G; McCreight, Katherine L

2006-01-01

.... In this report, we describe the foundations of a different type of computational architecture; one that we believe will be less susceptible to cognitive brittleness and can better scale to complex and ill-structured work domains...

Companion Cognitive Systems: A Step toward Human-Level AI

OpenAIRE

Forbus, Kenneth D.; Hinrichs, Thomas R.

2006-01-01

We are developing Companion Cognitive Systems, a new kind of software that can be effectively treated as a collaborator. Aside from their potential utility, we believe this effort is important because it focuses on three key problems that must be solved to achieve human-level AI: Robust reasoning and learning, interactivity, and longevity. We describe the ideas we are using to develop the first architecture for Companions: analogical processing, grounded in cognitive science for reasoning and...

Architecture

OpenAIRE

Clear, Nic

2014-01-01

When discussing science fiction’s relationship with architecture, the usual practice is to look at the architecture “in” science fiction—in particular, the architecture in SF films (see Kuhn 75-143) since the spaces of literary SF present obvious difficulties as they have to be imagined. In this essay, that relationship will be reversed: I will instead discuss science fiction “in” architecture, mapping out a number of architectural movements and projects that can be viewed explicitly as scien...

On evolution of thinking about semiosis: semiotics meets cognitive science

Directory of Open Access Journals (Sweden)

Piotr Konderak

2016-11-01

Full Text Available The aim of the paper is to sketch an idea—seen from the point of view of a cognitive scientist—of cognitive semiotics as a discipline. Consequently, the article presents aspects of the relationship between the two disciplines: semiotics and cognitive science. The main assumption of the argumentation is that at least some semiotic processes are also cognitive processes. At the methodological level, this claim allows for application of cognitive models as explanations of selected semiotic processes. In particular, the processes of embedded interpretation (in contrast to interpretability in principle are considered: belief revision, dynamic organization of meaning and metaknowledge. The explanations are formulated in terms of artificial cognitive agents of the GLAIR/SNePS cognitive architecture. Finally, it is suggested that even if someone rejects the idea of artificial cognitive systems as simulations of semiotic processes, they may acknowledge the usefulness of cognitive modeling in analysis of semiotic processes in virtual, simulated worlds and in the area of “new media”.

Screening of cognitive impairment in patients with Parkinson's disease: diagnostic validity of the Brazilian versions of the Montreal Cognitive Assessment and the Addenbrooke's Cognitive Examination-Revised.

Science.gov (United States)

Sobreira, Emmanuelle; Pena-Pereira, Márcio A; Eckeli, Alan L; Sobreira-Neto, Manoel A; Chagas, Marcos H N; Foss, Maria P; Cholerton, Brenna; Zabetian, Cyrus P; Mata, Ignacio F; Tumas, Vitor

2015-11-01

The aim of the present study is to examine the accuracy of the Brazilian versions of the Montreal Cognitive Assessment (MoCA) and the Addenbrooke's Cognitive Examination-Revised (ACE-R) to screen for mild cognitive impairment (PDMCI) and dementia (PDD) in patients with Parkinson's disease (PD). Both scales were administered to a final convenience sample of 79 patients with PD. Patients were evaluated by a neurologist, a psychiatrist and a neuropsychologist using UPDRS, Hoehn and Yahr and Schwab and England scales, global deterioration scale, a psychiatric structured interview, Mattis Dementia Rating Scale and other cognitive tests. There were 32 patients with PDMCI and 17 patients with PDD. The MoCA and the ACE-R were able to discriminate patients with PDD from the others. Both scales showed to be useful to screen for dementia but not for mild cognitive impairment in patients with PD.

Screening of cognitive impairment in patients with Parkinson's disease: diagnostic validity of the Brazilian versions of the Montreal Cognitive Assessment and the Addenbrooke's Cognitive Examination-Revised

Directory of Open Access Journals (Sweden)

Emmanuelle Sobreira

2015-11-01

Full Text Available ABSTRACTObjective The aim of the present study is to examine the accuracy of the Brazilian versions of the Montreal Cognitive Assessment (MoCA and the Addenbrooke's Cognitive Examination-Revised (ACE-R to screen for mild cognitive impairment (PDMCI and dementia (PDD in patients with Parkinson's disease (PD.Method Both scales were administered to a final convenience sample of 79 patients with PD. Patients were evaluated by a neurologist, a psychiatrist and a neuropsychologist using UPDRS, Hoehn and Yahr and Schwab and England scales, global deterioration scale, a psychiatric structured interview, Mattis Dementia Rating Scale and other cognitive tests.Results There were 32 patients with PDMCI and 17 patients with PDD. The MoCA and the ACE-R were able to discriminate patients with PDD from the others.Conclusion Both scales showed to be useful to screen for dementia but not for mild cognitive impairment in patients with PD.

Evolutionary, Unconscious Design Support for the Architectural, Engineering and Construction Industry

NARCIS (Netherlands)

Van de Ruitenbeek, H.K.M.

2012-01-01

The Architecture, Engineering and Construction (AEC) industry is a complex system in which carpenters, structural designers, architects, modellers, cost estimators, planners, politicians and many others act apart together in project-specific virtual enterprises. There is a large amount of actors, an

Managing Cognitive Load in Adaptive ICT-Based Learning

Directory of Open Access Journals (Sweden)

Slava Kalyuga

2009-10-01

Full Text Available The history of technological innovations in education has many examples of failed high expectations. To avoid becoming another one, current multimedia ICT tools need to be designed in accordance with how the human mind works. There are well established characteristics of its architecture that should be taken into account when evaluating, selecting, and using educational technology. This paper starts with a review of the most important features of human cognitive architecture and their implications for ICT-based learning. Expertise reversal effect relates to the interactions between levels of learner prior knowledge and effectiveness of different instructional techniques and procedures. Designs and techniques that are effective with low-knowledge learners can lose their effectiveness and even have negative consequences for more proficient learners. The paper describes recent empirical findings associated with the expertise reversal effect in multimedia and hypermedia learning environments, their interpretation within a cognitive load framework, and implications for the design of learner-tailored multimedia.

Compact, open-architecture computed radiography system

International Nuclear Information System (INIS)

Huang, H.K.; Lim, A.; Kangarloo, H.; Eldredge, S.; Loloyan, M.; Chuang, K.S.

1990-01-01

Computed radiography (CR) was introduced in 1982, and its basic system design has not changed. Current CR systems have certain limitations: spatial resolution and signal-to-noise ratios are lower than those of screen-film systems, they are complicated and expensive to build, and they have a closed architecture. The authors of this paper designed and implemented a simpler, lower-cost, compact, open-architecture CR system to overcome some of these limitations. The open-architecture system is a manual-load-single-plate reader that can fit on a desk top. Phosphor images are stored in a local disk and can be sent to any other computer through standard interfaces. Any manufacturer's plate can be read with a scanning time of 90 second for a 35 x 43-cm plate. The standard pixel size is 174 μm and can be adjusted for higher spatial resolution. The data resolution is 12 bits/pixel over an x-ray exposure range of 0.01-100 mR

Consequential Creativity: Student Competency and Lateral Thinking Incorporation in Architectural Education

Science.gov (United States)

Hamza, Tamer S.; Hassan, Doaa K.

2016-01-01

Creativity is an original cognitive ability and problem solving process which enables individuals to use their intelligence in a way that is unique and directed toward coming up with a product. Architectural education is one of the fields in which human creativity has been exhibited; because, it can be defined as a design study that correlates…

The NOAA Satellite Observing System Architecture Study

Science.gov (United States)

Volz, Stephen; Maier, Mark; Di Pietro, David

2016-01-01

NOAA is beginning a study, the NOAA Satellite Observing System Architecture (NSOSA) study, to plan for the future operational environmental satellite system that will follow GOES and JPSS, beginning about 2030. This is an opportunity to design a modern architecture with no pre-conceived notions regarding instruments, platforms, orbits, etc. The NSOSA study will develop and evaluate architecture alternatives to include partner and commercial alternatives that are likely to become available. The objectives will include both functional needs and strategic characteristics (e.g., flexibility, responsiveness, sustainability). Part of this study is the Space Platform Requirements Working Group (SPRWG), which is being commissioned by NESDIS. The SPRWG is charged to assess new or existing user needs and to provide relative priorities for observational needs in the context of the future architecture. SPRWG results will serve as input to the process for new foundational (Level 0 and Level 1) requirements for the next generation of NOAA satellites that follow the GOES-R, JPSS, DSCOVR, Jason-3, and COSMIC-2 missions.

Interactions between subunits of Saccharomyces cerevisiae RNase MRP support a conserved eukaryotic RNase P/MRP architecture.

Science.gov (United States)

Aspinall, Tanya V; Gordon, James M B; Bennett, Hayley J; Karahalios, Panagiotis; Bukowski, John-Paul; Walker, Scott C; Engelke, David R; Avis, Johanna M

2007-01-01

Ribonuclease MRP is an endonuclease, related to RNase P, which functions in eukaryotic pre-rRNA processing. In Saccharomyces cerevisiae, RNase MRP comprises an RNA subunit and ten proteins. To improve our understanding of subunit roles and enzyme architecture, we have examined protein-protein and protein-RNA interactions in vitro, complementing existing yeast two-hybrid data. In total, 31 direct protein-protein interactions were identified, each protein interacting with at least three others. Furthermore, seven proteins self-interact, four strongly, pointing to subunit multiplicity in the holoenzyme. Six protein subunits interact directly with MRP RNA and four with pre-rRNA. A comparative analysis with existing data for the yeast and human RNase P/MRP systems enables confident identification of Pop1p, Pop4p and Rpp1p as subunits that lie at the enzyme core, with probable addition of Pop5p and Pop3p. Rmp1p is confirmed as an integral subunit, presumably associating preferentially with RNase MRP, rather than RNase P, via interactions with Snm1p and MRP RNA. Snm1p and Rmp1p may act together to assist enzyme specificity, though roles in substrate binding are also indicated for Pop4p and Pop6p. The results provide further evidence of a conserved eukaryotic RNase P/MRP architecture and provide a strong basis for studies of enzyme assembly and subunit function.

Making fingers and words count in a cognitive robot

Directory of Open Access Journals (Sweden)

Vivian Milagros De La Cruz

2014-02-01

Full Text Available Evidence from developmental as well as neuroscientific studies suggest that finger counting activity plays an important role in the acquisition of numerical skills in children. It has been claimed that this skill helps in building motor-based representations of number that continue to influence number processing well into adulthood, facilitating the emergence of number concepts from sensorimotor experience through a bottom-up process. The act of counting also involves the acquisition and use of a verbal number system of which number words are the basic building blocks. Using a Cognitive Developmental Robotics paradigm we present results of a modeling experiment on whether finger counting and the association of number words (or tags to fingers, could serve to bootstrap the representation of number in a cognitive robot, enabling it to perform basic numerical operations such as addition. The cognitive architecture of the robot is based on artificial neural networks, which enable the robot to learn both sensorimotor skills (finger counting and linguistic skills (using number words. The results obtained in our experiments show that learning the number words in sequence along with finger configurations helps the fast building of the initial representation of number in the robot. Number knowledge, is instead, not as efficiently developed when number words are learned out of sequence without finger counting. Furthermore, the internal representations of the finger configurations themselves, developed by the robot as a result of the experiments, sustain the execution of basic arithmetic operations, something consistent with evidence coming from developmental research with children. The model and experiments demonstrate the importance of sensorimotor skill learning in robots for the acquisition of abstract knowledge such as numbers.

A framework for cognitive monitoring using computer game interactions.

Science.gov (United States)

Jimison, Holly B; Pavel, Misha; Bissell, Payton; McKanna, James

2007-01-01

Many countries are faced with a rapidly increasing economic and social challenge of caring for their elderly population. Cognitive issues are at the forefront of the list of concerns. People over the age of 75 are at risk for medically related cognitive decline and confusion, and the early detection of cognitive problems would allow for more effective clinical intervention. However, standard cognitive assessments are not diagnostically sensitive and are performed infrequently. To address these issues, we have developed a set of adaptive computer games to monitor cognitive performance in a home environment. Assessment algorithms for various aspects of cognition are embedded in the games. The monitoring of these metrics allows us to detect within subject trends over time, providing a method for the early detection of cognitive decline. In addition, the real-time information on cognitive state is used to adapt the user interface to the needs of the individual user. In this paper we describe the software architecture and methodology for monitoring cognitive performance using data from natural computer interactions in a home setting.

Modeling Architectural Patterns Using Architectural Primitives

NARCIS (Netherlands)

Zdun, Uwe; Avgeriou, Paris

2005-01-01

Architectural patterns are a key point in architectural documentation. Regrettably, there is poor support for modeling architectural patterns, because the pattern elements are not directly matched by elements in modeling languages, and, at the same time, patterns support an inherent variability that

Evaluation of Physicians' Cognitive Styles.

Science.gov (United States)

Djulbegovic, Benjamin; Beckstead, Jason W; Elqayam, Shira; Reljic, Tea; Hozo, Iztok; Kumar, Ambuj; Cannon-Bowers, Janis; Taylor, Stephanie; Tsalatsanis, Athanasios; Turner, Brandon; Paidas, Charles

2014-07-01

Patient outcomes critically depend on accuracy of physicians' judgment, yet little is known about individual differences in cognitive styles that underlie physicians' judgments. The objective of this study was to assess physicians' individual differences in cognitive styles relative to age, experience, and degree and type of training. Physicians at different levels of training and career completed a web-based survey of 6 scales measuring individual differences in cognitive styles (maximizing v. satisficing, analytical v. intuitive reasoning, need for cognition, intolerance toward ambiguity, objectivism, and cognitive reflection). We measured psychometric properties (Cronbach's α) of scales; relationship of age, experience, degree, and type of training; responses to scales; and accuracy on conditional inference task. The study included 165 trainees and 56 attending physicians (median age 31 years; range 25-69 years). All 6 constructs showed acceptable psychometric properties. Surprisingly, we found significant negative correlation between age and satisficing (r = -0.239; P = 0.017). Maximizing (willingness to engage in alternative search strategy) also decreased with age (r = -0.220; P = 0.047). Number of incorrect inferences negatively correlated with satisficing (r = -0.246; P = 0.014). Disposition to suppress intuitive responses was associated with correct responses on 3 of 4 inferential tasks. Trainees showed a tendency to engage in analytical thinking (r = 0.265; P = 0.025), while attendings displayed inclination toward intuitive-experiential thinking (r = 0.427; P = 0.046). However, trainees performed worse on conditional inference task. Physicians capable of suppressing an immediate intuitive response to questions and those scoring higher on rational thinking made fewer inferential mistakes. We found a negative correlation between age and maximizing: Physicians who were more advanced in their careers were less willing to spend time and effort in an

Interdisciplinary Interactions During R&D and Early Design of Large Engineered Systems

Science.gov (United States)

McGowan, Anna-Maria Rivas

2014-01-01

Designing Large-Scale Complex Engineered Systems (LaCES) such as aircraft and submarines requires the input of thousands of engineers and scientists whose work is proximate in neither time nor space. Comprehensive knowledge of the system is dispersed among specialists whose expertise is in typically one system component or discipline. This study examined the interactive work practices among such specialists seeking to improve engineering practice through a rigorous and theoretical understanding of current practice. This research explored current interdisciplinary practices and perspectives during R&D and early LaCES design and identified why these practices and perspectives prevail and persist. The research design consisted of a three-fold, integrative approach that combined an open-ended survey, semi-structured interviews, and ethnography. Significant empirical data from experienced engineers and scientists in a large engineering organization were obtained and integrated with theories from organization science and engineering. Qualitative analysis was used to obtain a holistic, contextualized understanding. The over-arching finding is that issues related to cognition, organization, and social interrelations mostly dominate interactions across disciplines. Engineering issues, such as the integration of hardware or physics-based models, are not as significant. For example, organization culture is an important underlying factor that guided researchers more toward individual sovereignty over cross-disciplinarity. The organization structure and the engineered system architecture also serve as constraints to the engineering work. Many differences in work practices were observed, including frequency and depth of interactions, definition or co-construction of requirements, clarity or creation of the system architecture, work group proximity, and cognitive challenges. Practitioners are often unaware of these differences resulting in confusion and incorrect assumptions

Assessment of cognitive function in patients with myasthenia gravis

Directory of Open Access Journals (Sweden)

Sherifa A Hamed

2014-12-01

Full Text Available Aim: During the past decade, there has been an increasing interest in the evaluation of cognitive function in myasthenia gravis (MG, neuromuscular transmission disorder caused by acetylcholine receptor auto-antibodies. However, the results of previous studies on cognition and MG are inconsistent and controversial. This study aimed to evaluate cognition in patients with mild/moderate grades of MG. Methods: This study included 20 patients with MG with a mean age of 28.45 ± 8.89 years and duration of illness of 3.52 ± 1.15 years. Cognition was tested using a sensitive battery of psychometric testing (Mini-mental State Examination [MMSE], Stanford-Binet Intelligence Scale 4 th edition [SBIS] and Wechsler Memory Scale-Revised [WMS-R] and by recording P300 component of event-related potentials (ERPs, a neurophysiological analog for cognitive function. Results: Compared with healthy subjects (n = 20, patients had lower total scores of cognitive testing (MMSE, SBIS and WMS-R (P = 0.001, higher Beck Depression Inventory 2 nd edition scores (P = 0.0001 and prolonged latencies (P = 0.01 and reduced amplitudes (P = 0.001 of P300 component of ERPs. Correlations were identified between total scores of cognitive testing and age (r = -0.470, P = 0.010, duration of illness (r = -0.788, P = 0.001 and depression scores (r = -0.323, P = 0.045. Using linear regression analysis and after controlling for age and depression scores, a significant correlation was identified between total scores of cognitive testing and duration of illness (β = -0.305, P = 0.045. Conclusion: Patients with mild/moderate MG may have cognitive dysfunction. This is important to determine prognosis and managing patients.

HiMoP: A three-component architecture to create more human-acceptable social-assistive robots : Motivational architecture for assistive robots.

Science.gov (United States)

Rodríguez-Lera, Francisco J; Matellán-Olivera, Vicente; Conde-González, Miguel Á; Martín-Rico, Francisco

2018-05-01

Generation of autonomous behavior for robots is a general unsolved problem. Users perceive robots as repetitive tools that do not respond to dynamic situations. This research deals with the generation of natural behaviors in assistive service robots for dynamic domestic environments, particularly, a motivational-oriented cognitive architecture to generate more natural behaviors in autonomous robots. The proposed architecture, called HiMoP, is based on three elements: a Hierarchy of needs to define robot drives; a set of Motivational variables connected to robot needs; and a Pool of finite-state machines to run robot behaviors. The first element is inspired in Alderfer's hierarchy of needs, which specifies the variables defined in the motivational component. The pool of finite-state machine implements the available robot actions, and those actions are dynamically selected taking into account the motivational variables and the external stimuli. Thus, the robot is able to exhibit different behaviors even under similar conditions. A customized version of the "Speech Recognition and Audio Detection Test," proposed by the RoboCup Federation, has been used to illustrate how the architecture works and how it dynamically adapts and activates robots behaviors taking into account internal variables and external stimuli.

The unity of Luke-Acts

Directory of Open Access Journals (Sweden)

J. Verheyden

1999-12-01

Full Text Available The article contains a summary of contributions delivered at he 47th Colloquium Biblicum Lovaniense (1998 held at the Catholic University, Leuven on the subject: "The unity of Luke-Acts". The opening address was delivered by J Verheyden (Leuven on "The Unity of Luke and Acts: What are we up to?". The contributors were: J Kremer (Vienna - "Die dreifache Wiedergabe des Damaskuserlebnis Pauli in der Apostelgeschichte: Eine Hilfe für das rechte Verständnis der lukanischen Osterevangelien"; D Marguerat (Lausanne -"Jusqu' où faut-il parler d'une "unité". Luc-Actes? Continuity et ruptures dans I'ævre de Luc"; JDelobel (Leuven - "The text of Luke-Acts: A confrontation of recent theories"; R L Brawley (Chicago - "Abrahamic covenant traditions and the characterization of God in Luke-Acts"; F W Horn (Mainz - "Die Haltung des Lukas zum römischen Staat im Evangelium und in der Apostelgeschichte"; J A Fitzmyer (Washington - "The role of theSpirit in Luke-Acts"; M Rese (Munster - "The Jews in Luke-Acts: Some secondthoughts"; J Taylor (Jerusalem - "La fraction du pain en Luc-Actes"; W Radl (Augs-burg - "Die Beziehungen der Vorgeschichte zur Apostelgeschichte, dargestellt an Lk 2:22-39; F Neirynck (Leuven - "Luke 4:16-30 and the unity of Luke-Acts"; C M Tuckett (Oxford - "The Christology of Luke-Acts"; O Mainville (Montreal - "Le messianisme de Jésus: Le rapport announce/accomplissement entre Lc 1,35 et Ac 2,33"; A Lindemann (Bethel-Bielefeld - "Form und Funktion von Reden und Wundererzählungen im Lukas-evangelium und in der Apostelgeschichte", A Denaux - The theme of divine visits and human (inhospitability in Luke-Acts and its Old Testament and Graeco-Roman antecedents.

rKnowledge: The Spatial Diffusion of rDNA Methods

OpenAIRE

Maryann Feldman; Dieter Kogler; David Rigby

2013-01-01

The 1980 patent granted to Stanley Cohen and Herbert Boyer for their development of rDNA technology played a critical role in the establishment of the modern biotechnology industry. From the birth of this general purpose technology in the San Francisco Bay area, rDNA-related knowledge diffused across sectors and regions of the U.S. economy. The local absorption and application of rDNA technology is tracked across metropolitan areas with USPTO patent data. The influence of cognitive, geographi...

Rune Frederiksen, Elizabeth R. Gebhard & Alexander Sokolicek (eds.), The Architecture of the Ancient Greek Theatre, Monographs of the Danish Institute, Volume 17 (Aarhus: Aarhus University Press and The Danish Institute at Athens, 2015)

OpenAIRE

William C. Miller

2017-01-01

A review of the book: Rune Frederiksen, Elizabeth R. Gebhard & Alexander Sokolicek (eds.), The Architecture of the Ancient Greek Theatre, Monographs of the Danish Institute, Volume 17 (Aarhus: Aarhus University Press and The Danish Institute at Athens, 2015)

Federal Pay Equity Act of 1984. Part 1. Hearings before the Subcommittee on Compensation and Employee Benefits of the Committee on Post Office and Civil Service, House of Representatives, Ninety-Eighth Congress, Second Session on H.R. 4599...and H.R. 5092. (April 3-4, 1984).

Science.gov (United States)

Congress of the U. S., Washington, DC. House Committee on Post Office and Civil Service.

This document contains two congressional hearings on H.R. 4599, the Federal Pay Equity Act of 1984, and H.R. 5092, the Pay Equity Act of 1984. These bills would mandate the Office of Personnel Management to study wage discrepancies in the Federal classification structure and to devise a more equitable job evaluation program and would require…

Expression profiling of miR-96, miR-584 and miR-422a in colon ...

African Journals Online (AJOL)

Purpose: To determine the correlation between miRNAs; miR-96, miR-422a and miR584, and colon cancer, and also to test whether any of these miRNAs can act as non-invasive biomarkers in colon cancer. Methods: The tumor samples and the corresponding normal mucosa used in this study were collected from 60 ...

Personality Is Reflected in the Brain's Intrinsic Functional Architecture

Science.gov (United States)

Adelstein, Jonathan S.; Shehzad, Zarrar; Mennes, Maarten; DeYoung, Colin G.; Zuo, Xi-Nian; Kelly, Clare; Margulies, Daniel S.; Bloomfield, Aaron; Gray, Jeremy R.; Castellanos, F. Xavier; Milham, Michael P.

2011-01-01

Personality describes persistent human behavioral responses to broad classes of environmental stimuli. Investigating how personality traits are reflected in the brain's functional architecture is challenging, in part due to the difficulty of designing appropriate task probes. Resting-state functional connectivity (RSFC) can detect intrinsic activation patterns without relying on any specific task. Here we use RSFC to investigate the neural correlates of the five-factor personality domains. Based on seed regions placed within two cognitive and affective ‘hubs’ in the brain—the anterior cingulate and precuneus—each domain of personality predicted RSFC with a unique pattern of brain regions. These patterns corresponded with functional subdivisions responsible for cognitive and affective processing such as motivation, empathy and future-oriented thinking. Neuroticism and Extraversion, the two most widely studied of the five constructs, predicted connectivity between seed regions and the dorsomedial prefrontal cortex and lateral paralimbic regions, respectively. These areas are associated with emotional regulation, self-evaluation and reward, consistent with the trait qualities. Personality traits were mostly associated with functional connections that were inconsistently present across participants. This suggests that although a fundamental, core functional architecture is preserved across individuals, variable connections outside of that core encompass the inter-individual differences in personality that motivate diverse responses. PMID:22140453

Personality is reflected in the brain's intrinsic functional architecture.

Directory of Open Access Journals (Sweden)

Jonathan S Adelstein

Full Text Available Personality describes persistent human behavioral responses to broad classes of environmental stimuli. Investigating how personality traits are reflected in the brain's functional architecture is challenging, in part due to the difficulty of designing appropriate task probes. Resting-state functional connectivity (RSFC can detect intrinsic activation patterns without relying on any specific task. Here we use RSFC to investigate the neural correlates of the five-factor personality domains. Based on seed regions placed within two cognitive and affective 'hubs' in the brain--the anterior cingulate and precuneus--each domain of personality predicted RSFC with a unique pattern of brain regions. These patterns corresponded with functional subdivisions responsible for cognitive and affective processing such as motivation, empathy and future-oriented thinking. Neuroticism and Extraversion, the two most widely studied of the five constructs, predicted connectivity between seed regions and the dorsomedial prefrontal cortex and lateral paralimbic regions, respectively. These areas are associated with emotional regulation, self-evaluation and reward, consistent with the trait qualities. Personality traits were mostly associated with functional connections that were inconsistently present across participants. This suggests that although a fundamental, core functional architecture is preserved across individuals, variable connections outside of that core encompass the inter-individual differences in personality that motivate diverse responses.

Paraconsistent semantics of speech acts

NARCIS (Netherlands)

Dunin-Kȩplicz, Barbara; Strachocka, Alina; Szałas, Andrzej; Verbrugge, Rineke

2015-01-01

This paper discusses an implementation of four speech acts: assert, concede, request and challenge in a paraconsistent framework. A natural four-valued model of interaction yields multiple new cognitive situations. They are analyzed in the context of communicative relations, which partially replace

Computational models of music perception and cognition I: The perceptual and cognitive processing chain

Science.gov (United States)

Purwins, Hendrik; Herrera, Perfecto; Grachten, Maarten; Hazan, Amaury; Marxer, Ricard; Serra, Xavier

2008-09-01

We present a review on perception and cognition models designed for or applicable to music. An emphasis is put on computational implementations. We include findings from different disciplines: neuroscience, psychology, cognitive science, artificial intelligence, and musicology. The article summarizes the methodology that these disciplines use to approach the phenomena of music understanding, the localization of musical processes in the brain, and the flow of cognitive operations involved in turning physical signals into musical symbols, going from the transducers to the memory systems of the brain. We discuss formal models developed to emulate, explain and predict phenomena involved in early auditory processing, pitch processing, grouping, source separation, and music structure computation. We cover generic computational architectures of attention, memory, and expectation that can be instantiated and tuned to deal with specific musical phenomena. Criteria for the evaluation of such models are presented and discussed. Thereby, we lay out the general framework that provides the basis for the discussion of domain-specific music models in Part II.

A Sensitive Secondary Users Selection Algorithm for Cognitive Radio Ad Hoc Networks

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Aohan Li

2016-03-01

Full Text Available Secondary Users (SUs are allowed to use the temporarily unused licensed spectrum without disturbing Primary Users (PUs in Cognitive Radio Ad Hoc Networks (CRAHNs. Existing architectures for CRAHNs impose energy-consuming Cognitive Radios (CRs on SUs. However, the advanced CRs will increase energy cost for their cognitive functionalities, which is undesirable for the battery powered devices. A new architecture referred to as spectral Requirement-based CRAHN (RCRAHN is proposed to enhance energy efficiency for CRAHNs in this paper. In RCRAHNs, only parts of SUs are equipped with CRs. SUs equipped with CRs are referred to as Cognitive Radio Users (CRUs. To further enhance energy efficiency of CRAHNs, we aim to select minimum CRUs to sense available spectrum. A non-linear programming problem is mathematically formulated under the constraints of energy efficiency and real-time. Considering the NP-hardness of the problem, a framework of a heuristic algorithm referred to as Sensitive Secondary Users Selection (SSUS was designed to compute the near-optimal solutions. The simulation results demonstrate that SSUS not only improves the energy efficiency, but also achieves satisfied performances in end-to-end delay and communication reliability.

A Sensitive Secondary Users Selection Algorithm for Cognitive Radio Ad Hoc Networks.

Science.gov (United States)

Li, Aohan; Han, Guangjie; Wan, Liangtian; Shu, Lei

2016-03-26

Secondary Users (SUs) are allowed to use the temporarily unused licensed spectrum without disturbing Primary Users (PUs) in Cognitive Radio Ad Hoc Networks (CRAHNs). Existing architectures for CRAHNs impose energy-consuming Cognitive Radios (CRs) on SUs. However, the advanced CRs will increase energy cost for their cognitive functionalities, which is undesirable for the battery powered devices. A new architecture referred to as spectral Requirement-based CRAHN (RCRAHN) is proposed to enhance energy efficiency for CRAHNs in this paper. In RCRAHNs, only parts of SUs are equipped with CRs. SUs equipped with CRs are referred to as Cognitive Radio Users (CRUs). To further enhance energy efficiency of CRAHNs, we aim to select minimum CRUs to sense available spectrum. A non-linear programming problem is mathematically formulated under the constraints of energy efficiency and real-time. Considering the NP-hardness of the problem, a framework of a heuristic algorithm referred to as Sensitive Secondary Users Selection (SSUS) was designed to compute the near-optimal solutions. The simulation results demonstrate that SSUS not only improves the energy efficiency, but also achieves satisfied performances in end-to-end delay and communication reliability.

On the interference suppression capabilities of cognitive enabled femto cellular networks

KAUST Repository

Shakir, Muhammad; Atat, Rachad; Alouini, Mohamed-Slim

2012-01-01

Cognitive Radios are considered as a standard part of future Heterogeneous mobile network architecture. In this paper, we consider a two tier Heterogeneous network with multiple radio access technologies (RATS) namely; (i) the secondary network

IAA-Ala Resistant3, an evolutionarily conserved target of miR167, mediates Arabidopsis root architecture changes during high osmotic stress

KAUST Repository

Kinoshita, Natsuko

2012-09-01

The functions of microRNAs and their target mRNAs in Arabidopsis thaliana development have been widely documented; however, roles of stress-responsive microRNAs and their targets are not as well understood. Using small RNA deep sequencing and ATH1 microarrays to profile mRNAs, we identified IAA-Ala Resistant3 (IAR3) as a new target of miR167a. As expected, IAR3 mRNA was cleaved at the miR167a complementary site and under high osmotic stress miR167a levels decreased, whereas IAR3 mRNA levels increased. IAR3 hydrolyzes an inactive form of auxin (indole-3-acetic acid [IAA]-alanine) and releases bioactive auxin (IAA), a central phytohormone for root development. In contrast with the wild type, iar3 mutants accumulated reduced IAA levels and did not display high osmotic stress-induced root architecture changes. Transgenic plants expressing a cleavage-resistant form of IAR3 mRNA accumulated high levels of IAR3 mRNAs and showed increased lateral root development compared with transgenic plants expressing wild-type IAR3. Expression of an inducible noncoding RNA to sequester miR167a by target mimicry led to an increase in IAR3 mRNA levels, further confirming the inverse relationship between the two partners. Sequence comparison revealed the miR167 target site on IAR3 mRNA is conserved in evolutionarily distant plant species. Finally, we showed that IAR3 is required for drought tolerance. © 2012 American Society of Plant Biologists. All rights reserved.

IAA-Ala Resistant3, an evolutionarily conserved target of miR167, mediates Arabidopsis root architecture changes during high osmotic stress

KAUST Repository

Kinoshita, Natsuko; Wang, Huan; Kasahara, Hiroyuki; Liu, Jun; MacPherson, Cameron R.; Machida, Yasunori; Kamiya, Yuji; Hannah, Matthew A.; Chuaa, Nam Hai

2012-01-01

The functions of microRNAs and their target mRNAs in Arabidopsis thaliana development have been widely documented; however, roles of stress-responsive microRNAs and their targets are not as well understood. Using small RNA deep sequencing and ATH1 microarrays to profile mRNAs, we identified IAA-Ala Resistant3 (IAR3) as a new target of miR167a. As expected, IAR3 mRNA was cleaved at the miR167a complementary site and under high osmotic stress miR167a levels decreased, whereas IAR3 mRNA levels increased. IAR3 hydrolyzes an inactive form of auxin (indole-3-acetic acid [IAA]-alanine) and releases bioactive auxin (IAA), a central phytohormone for root development. In contrast with the wild type, iar3 mutants accumulated reduced IAA levels and did not display high osmotic stress-induced root architecture changes. Transgenic plants expressing a cleavage-resistant form of IAR3 mRNA accumulated high levels of IAR3 mRNAs and showed increased lateral root development compared with transgenic plants expressing wild-type IAR3. Expression of an inducible noncoding RNA to sequester miR167a by target mimicry led to an increase in IAR3 mRNA levels, further confirming the inverse relationship between the two partners. Sequence comparison revealed the miR167 target site on IAR3 mRNA is conserved in evolutionarily distant plant species. Finally, we showed that IAR3 is required for drought tolerance. © 2012 American Society of Plant Biologists. All rights reserved.

Rune Frederiksen, Elizabeth R. Gebhard & Alexander Sokolicek (eds., The Architecture of the Ancient Greek Theatre, Monographs of the Danish Institute, Volume 17 (Aarhus: Aarhus University Press and The Danish Institute at Athens, 2015

Directory of Open Access Journals (Sweden)

William C. Miller

2017-03-01

Full Text Available A review of the book: Rune Frederiksen, Elizabeth R. Gebhard & Alexander Sokolicek (eds., The Architecture of the Ancient Greek Theatre, Monographs of the Danish Institute, Volume 17 (Aarhus: Aarhus University Press and The Danish Institute at Athens, 2015

High-Level Design Space and Flexibility Exploration for Adaptive, Energy-Efficient WCDMA Channel Estimation Architectures

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Zoltán Endre Rákossy

2012-01-01

Full Text Available Due to the fast changing wireless communication standards coupled with strict performance constraints, the demand for flexible yet high-performance architectures is increasing. To tackle the flexibility requirement, software-defined radio (SDR is emerging as an obvious solution, where the underlying hardware implementation is tuned via software layers to the varied standards depending on power-performance and quality requirements leading to adaptable, cognitive radio. In this paper, we conduct a case study for representatives of two complexity classes of WCDMA channel estimation algorithms and explore the effect of flexibility on energy efficiency using different implementation options. Furthermore, we propose new design guidelines for both highly specialized architectures and highly flexible architectures using high-level synthesis, to enable the required performance and flexibility to support multiple applications. Our experiments with various design points show that the resulting architectures meet the performance constraints of WCDMA and a wide range of options are offered for tuning such architectures depending on power/performance/area constraints of SDR.

NDN-CRAHNs: Named Data Networking for Cognitive Radio Ad Hoc Networks

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Rana Asif Rehman

2015-01-01

Full Text Available Named data networking (NDN is a newly proposed paradigm for future Internet, in which communication among nodes is based on data names, decoupling from their locations. In dynamic and self-organized cognitive radio ad hoc networks (CRAHNs, it is difficult to maintain end-to-end connectivity between ad hoc nodes especially in the presence of licensed users and intermittent wireless channels. Moreover, IP-based CRAHNs have several issues like scalability, inefficient-mapping, poor resource utilization, and location dependence. By leveraging the advantages of NDN, in this paper, we propose a new cross layer fine-grained architecture called named data networking for cognitive radio ad hoc networks (NDN-CRAHNs. The proposed architecture provides distinct features such as in-networking caching, security, scalability, and multipath routing. The performances of the proposed scheme are evaluated comparing to IP-based scheme in terms of average end-to-end delay and packet delivery ratio. Simulation results show that the proposed scheme is effective in terms of average contents download time and packet delivery ratios comparing to conventional cognitive radio ad hoc networks.

Trait susceptibility to worry modulates the effects of cognitive load on cognitive control: An ERP study.

Science.gov (United States)

Owens, Max; Derakshan, Nazanin; Richards, Anne

2015-10-01

According to the predictions of attentional control theory (ACT) of anxiety (Eysenck, Derakshan, Santos, & Calvo, 2007), worry is a central feature of anxiety that interferes with the ability to inhibit distracting information necessary for successful task performance. However, it is unclear how such cognitive control deficits are modulated by task demands and by the emotionality of the distractors. A sample of 31 participants (25 female) completed a novel flanker task with emotional and neutral distractors under low- and high-cognitive-load conditions. The negative-going N2 event-related potential was measured to index participants' level of top-down resource allocation in the inhibition of distractors under high- and low-load conditions. Results showed N2 amplitudes were larger under high- compared with low-load conditions. In addition, under high but not low load, trait worry was associated with greater N2 amplitudes. Our findings support ACT predictions that trait worry adversely affects goal-directed behavior, and is associated with greater recruitment of cognitive resources to inhibit the impact of distracting information under conditions in which cognitive resources are taxed. (c) 2015 APA, all rights reserved).

The relationship between diabetic retinopathy and cognitive impairment.

Science.gov (United States)

Crosby-Nwaobi, Roxanne R; Sivaprasad, Sobha; Amiel, Stephanie; Forbes, Angus

2013-10-01

Recent studies have shown an increased risk for cognitive impairment and dementia in patients with diabetes. An association between diabetic retinopathy (DR) and retinal microvasculature disease and cognitive impairment has been reported as potential evidence for a microvascular component to the cognitive impairment. It was hypothesized that severity of DR would be associated with cognitive impairment in individuals with type 2 diabetes. Three hundred eighty patients with type 2 diabetes were recruited from a population-based eye screening program and grouped by severity of DR as follows: no/mild DR (n=252) and proliferative diabetic retinopathy (PDR) (n=128). Each participant underwent psychosocial assessment; depression screening; ophthalmic and physical examination, including blood assays; and cognitive assessment with the Addenbrooke's Cognitive Examination-Revised (ACE-R), Mini-Mental State Examination (MMSE), and the Mini-Cog. General linear modeling was used to examine severity of DR and cognitive impairment, adjusting for confounders. Severity of DR demonstrated an inverse relationship with cognitive impairment (fully adjusted R2=0.415, Pcognitive impairment scores on ACE-R (adjusted mean±SE 77.0±1.9) compared with the PDR group (82.5±2.2, Pcognitive impairment compared with 5% in the PDR group (n=6). Patients with minimal DR demonstrated more cognitive impairment than those with advanced DR. Therefore, the increased prevalence of cognitive impairment in diabetes may be associated with factors other than evident retinal microvascular disease.

The effect of intermittent fasting during Ramadan on sleep, sleepiness, cognitive function, and circadian rhythm.

Science.gov (United States)

Qasrawi, Shaden O; Pandi-Perumal, Seithikurippu R; BaHammam, Ahmed S

2017-09-01

Studies have shown that experimental fasting can affect cognitive function, sleep, and wakefulness patterns. However, the effects of experimental fasting cannot be generalized to fasting during Ramadan due to its unique characteristics. Therefore, there has been increased interest in studying the effects of fasting during Ramadan on sleep patterns, daytime sleepiness, cognitive function, sleep architecture, and circadian rhythm. In this review, we critically discuss the current research findings in those areas during the month of Ramadan. Available data that controlled for sleep/wake schedule, sleep duration, light exposure, and energy expenditure do not support the notion that Ramadan intermittent fasting increases daytime sleepiness and alters cognitive function. Additionally, recent well-designed studies showed no effect of fasting on circadian rhythms. However, in non-constrained environments that do not control for lifestyle changes, studies have demonstrated sudden and significant delays in bedtime and wake time. Studies that controlled for environmental factors and sleep/wake schedule reported no significant disturbances in sleep architecture. Nevertheless, several studies have consistently reported that the main change in sleep architecture during fasting is a reduction in the proportion of REM sleep.

Deconstructing and Reconstructing Cognitive Performance in Sleep Deprivation

Science.gov (United States)

Jackson, Melinda L.; Gunzelmann, Glenn; Whitney, Paul; Hinson, John M.; Belenky, Gregory; Rabat, Arnaud; Van Dongen, Hans P. A.

2012-01-01

Summary Mitigation of cognitive impairment due to sleep deprivation in operational settings is critical for safety and productivity. Achievements in this area are hampered by limited knowledge about the effects of sleep loss on actual job tasks. Sleep deprivation has different effects on different cognitive performance tasks, but the mechanisms behind this task-specificity are poorly understood. In this context it is important to recognize that cognitive performance is not a unitary process, but involves a number of component processes. There is emerging evidence that these component processes are differentially affected by sleep loss. Experiments have been conducted to decompose sleep-deprived performance into underlying cognitive processes using cognitive-behavioral, neuroimaging and cognitive modeling techniques. Furthermore, computational modeling in cognitive architectures has been employed to simulate sleep-deprived cognitive performance on the basis of the constituent cognitive processes. These efforts are beginning to enable quantitative prediction of the effects of sleep deprivation across different task contexts. This paper reviews a rapidly evolving area of research, and outlines a theoretical framework in which the effects of sleep loss on cognition may be understood from the deficits in the underlying neurobiology to the applied consequences in real-world job tasks. PMID:22884948

Stereotypical architecture of the stem cell niche is spatiotemporally established by miR-125-dependent coordination of Notch and steroid signaling.

Science.gov (United States)

Yatsenko, Andriy S; Shcherbata, Halyna R

2018-02-08

Stem cell niches act as signaling platforms that regulate stem cell self-renewal and sustain stem cells throughout life; however, the specific developmental events controlling their assembly are not well understood. Here, we show that during Drosophila ovarian germline stem cell niche formation, the status of Notch signaling in the cell can be reprogrammed. This is controlled via steroid-induced miR-125 , which targets a negative regulator of Notch signaling, Tom. Thus, miR-125 acts as a spatiotemporal coordinator between paracrine Notch and endocrine steroid signaling. Moreover, a dual security mechanism for Notch signaling activation exists to ensure the robustness of niche assembly. Particularly, stem cell niche cells can be specified either via lateral inhibition, in which a niche cell precursor acquires Notch signal-sending status randomly, or via peripheral induction, whereby Delta is produced by a specific cell. When one mechanism is perturbed due to mutations, developmental defects or environmental stress, the remaining mechanism ensures that the niche is formed, perhaps abnormally, but still functional. This guarantees that the germline stem cells will have their residence, thereby securing progressive oogenesis and, thus, organism reproduction. © 2018. Published by The Company of Biologists Ltd.

A systematic review of protocol studies on conceptual design cognition: design as search and exploration

OpenAIRE

Hay, Laura; Duffy, Alex H.B.; McTeague, Chris; Pidgeon, Laura M.; Vuletic, Tijana; Grealy, Madeleine

2017-01-01

This paper reports findings from the first systematic review of protocol studies focusing specifically on conceptual design cognition, aiming to answer the following research question: What is our current understanding of the cognitive processes involved in conceptual design tasks carried out by individual designers? We reviewed 47 studies on architectural design, engineering design and product design engineering. This paper reports 24 cognitive processes investigated in a subset of 33 studie...

Practical evaluation of organic polymer thermoelectrics by large-area R2R processing on flexible substrates

OpenAIRE

Søndergaard, Roar R.; Hösel, Markus; Espinosa Martinez, Nieves; Jørgensen, Mikkel; Krebs, Frederik C

2013-01-01

Here, we present a process based on roll-to-roll (R2R) technology which allows for very fast processing of polymer thermoelectric (TE) devices and we furthermore demonstrate a simplified but more efficient way of serially connecting these devices by means of R2R thin-film processing. The new device architecture makes it possible to use only one TE material (opposed to two materials which are employed in well-known Peltier elements), and a total of 18,000 serially connected junctions were prep...

Children's Behaviour and Cognitions across Different Balance Tasks

Science.gov (United States)

Messer, David J.; Pine, Karen J.; Butler, Cathal

2008-01-01

Children's understanding of the way objects balance has provided important insights about cognitive development [e.g., Karmiloff-Smith, A. (1992). "Beyond modularity: A developmental perspective on cognitive science." Cambridge, MA: MIT Press; Siegler, R. S. (1976). Three aspects of cognitive development. "Cognitive Psychology," 8, 481-520]. We…

Acceptance and commitment therapy: the new wave of cognitive behavior therapy

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Wahyu Nanda Eka Saputra

2016-12-01

Full Text Available Cognitive behavior therapy (CBT is one of the major counseling theories today. However, reliability of this theory has received criticism from other theories, which claim to cognitive interventions do not provide added value on behavioral interventions. The theory criticized and showed dissatisfaction with the practice of CBT is the theory of Acceptance and Commitment Therapy (ACT. Furthermore, ACT is known to a new generation of CBT.ACT is one of the new counseling approach that can be applied to school counselors to deal with the issues of students in the school.

Differential Impact of miR-21 on Pain and Associated Affective and Cognitive Behavior after Spared Nerve Injury in B7-H1 ko Mouse

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Franziska Karl

2017-07-01

Full Text Available MicroRNAs (miRNAs are increasingly recognized as regulators of immune and neuronal gene expression and are potential master switches in neuropathic pain pathophysiology. miR-21 is a promising candidate that may link the immune and the pain system. To investigate the pathophysiological role of miR-21 in neuropathic pain, we assessed mice deficient of B7 homolog 1 (B7-H1, a major inhibitor of inflammatory responses. In previous studies, an upregulation of miR-21 had been shown in mouse lymphocytes. Young (8 weeks, middle-aged (6 months, and old (12 months B7-H1 ko mice and wildtype littermates (WT received a spared nerve injury (SNI. We assessed thermal withdrawal latencies and mechanical withdrawal thresholds. Further, we performed tests for anxiety-like and cognitive behavior. Quantitative real time PCR was used to determine miR-21 relative expression in peripheral nerves, and dorsal root ganglia (DRG at distinct time points after SNI. We found mechanical hyposensitivity with increasing age of naïve B7-H1 ko mice. Young and middle-aged B7-H1 ko mice were more sensitive to mechanical stimuli compared to WT mice (young: p < 0.01, middle-aged: p < 0.05. Both genotypes developed mechanical and heat hypersensitivity (p < 0.05 after SNI, without intergroup differences. No relevant differences were found after SNI in three tests for anxiety like behavior in B7-H1 ko and WT mice. Also, SNI had no effect on cognition. B7-H1 ko and WT mice showed a higher miR-21 expression (p < 0.05 and invasion of macrophages and T cells in the injured nerve 7 days after SNI without intergroup differences. Our study reveals that increased miR-21 expression in peripheral nerves after SNI is associated with reduced mechanical and heat withdrawal thresholds. These results point to a role of miR-21 in the pathophysiology of neuropathic pain, while affective behavior and cognition seem to be spared. Contrary to expectations, B7-H1 ko mice did not show higher miR-21

Cognitive Architecture and the Epistemic Gap: Defending Physicalism without Phenomenal Concepts

DEFF Research Database (Denmark)

Fazekas, Peter

2011-01-01

The novel approach presented in this paper accounts for the occurrence of the epistemic gap and defends physicalism against anti-physicalist arguments without relying on so-called phenomenal concepts. Instead of concentrating on conceptual features, the focus is shifted to the special...... characteristics of experiences themselves. To this extent, the account provided is an alternative to the Phenomenal Concept Strategy. It is argued that certain sensory representations, as accessed by higher cognition, lack constituent structure. Unstructured representations could freely exchange their causal...... to pose a serious problem for contemporary physicalism. I conclude that if those concepts which are related to the phenomenal character of conscious experience are special in any way, their characteristics are derivative of and can be accounted for in terms of the cognitive and representational features...

Long non-coding RNA TUG1 acts as a miR-26a sponge in human glioma cells.

Science.gov (United States)

Li, Jun; An, Gang; Zhang, Meng; Ma, Qingfang

2016-09-02

Long non-coding RNA taurine upregulated gene 1 (TUG1) acts as an important regulator in cancer pathogenesis; however, its functional mechanism in glioma development remains unclear. This study aims to explore the potential function of TUG1 in glioma by sponging miR-26a. The expression of TUG1, miR-26a, and phosphatase and tensin homolog (PTEN) in 20 paired glioma tissues was detected by quantitative real-time PCR and subjected to correlation analysis. Bioinformatics analysis was performed by using DIANA Tools. Abnormal TUG1 expression was conducted in two glioma cells to analyze its regulation on miR-26a and PTEN using real-time PCR, western blot, and luciferase reporter assay. TUG1 expression was confirmed to be upregulated in glioma tissues, and showed an inverse correlation with downregulated miR-26a. TUG1 could negatively regulate the expression of miR-26a in glioma cells. The bioinformatics prediction revealed putative miR-26a binding sites within TUG1 transcripts. Further experiments demonstrated the positive regulation of TUG1 on the miR-26a target, PTEN, wherein TUG1 could inhibit the negative regulation of miR-26a on PTEN by binding its 3'UTR. Additionally, the expression of PTEN was also upregulated in glioma tissues, showing a positive or negative correlation with TUG1 or miR-26a, respectively. TUG1 could serve as a miR-26a sponge in human glioma cells, contributing to the upregulation of PTEN. This study revealed a new TUG1/miR-26a/PTEN regulatory mechanism and provided a further understanding of the tumor-suppressive role of TUG1 in glioma development. Copyright © 2016 Elsevier Inc. All rights reserved.

[Psychometric properties and diagnostic usefulness of the Addenbrooke's Cognitive Examination-Revised in a Chilean elderly sample].

Science.gov (United States)

Muñoz-Neira, Carlos; Henríquez Ch, Fernando; Ihnen J, Josefina; Sánchez C, Mauricio; Flores M, Patricia; Slachevsky Ch, Andrea

2012-08-01

The Addenbrooke's Cognitive Examination - Revised (ACE-R) is a good alternative to the Mini Mental State Examination (MMSE) for assessing cognitive capacities in dementia. To estimate the psychometric properties and diagnostic utility of the Addenbrooke's Cognitive Examination-Revised (ACE-R) in a Chilean elderly sample. ACE-R was adapted for the Chilean population (ACE-R-Ch) and then administered to 60 dementia patients, 22 mild cognitive impairment (MCI) patients and 45 control subjects in addition to the MMSE for assessing global cognitive efficiency. Caregivers of dementia patients and collateral sources of MCI patients and elderly subjects without dementia were interviewed with measures of dementia severity, functional status in activities of daily living and cognitive changes. Convergent validity, internal consistency reliability, cutoff points, sensitivity and specificity for ACE-R-Ch were estimated. Regarding convergent validity, the ACE-R-Ch showed significant correlations (p cognitive measure (r = 0,952 with MMSE), a rating for dementia severity (Spearman rho=-0,822 with CDR), functional capacity assessments (r = -0,70 with ADLQ-Ch; r = -0,725 with PFAQ-Ch; and r = 0,650 with IADL Scale) and a measure of cognitive changes (r = -0,633 with AD8-Ch). In terms of reliability, the test had a Cronbach alpha coefficient of 0.918. The best cut-off point to distinguish cases of dementia from control subjects was a score of 76, which reached a sensitivity of 0.92 and a specificity of 0.93. The ACE-R-Ch showed acceptable psychometric properties, becoming a valid and reliable instrument to assess global cognitive efficiency or cognitive impairment. Its diagnostic utility to detect dementia patients also worked very well in a Chilean elderly sample.

Application of Fuzzy theory with neutral network and cognitive map on decision making

International Nuclear Information System (INIS)

Hla Aung; Tin Maung

2001-01-01

The format reasoning involves establishment of causal relationships among concepts. These are commonly represented by cognitive maps. However, the concepts and their relationships could be fuzzy. In this paper we review some properties of fuzzy cognitive maps. This paper shows that one of the solutions is to introduce the idea of disconcepts along with concepts to arrive at reasonings that are intuitively satisfying. A neutral network architecture based on associative memory and a framework for fuzzy cognitive maps based knowledge processing tool has also been proposed. The proposed method is tested on a cognitive map of a publishing company. (author)

Central system of Interlock of ITER, high integrity architecture

International Nuclear Information System (INIS)

Prieto, I.; Martinez, G.; Lopez, C.

2014-01-01

The CIS (Central Interlock System), along with the CODAC system and CSS (Central Safety System), form the central I and C systems of ITER. The CIS is responsible for implementing the core functions of protection (Central Interlock Functions) through different systems of plant (Plant Systems) within the overall strategy of investment protection for ITER. IBERDROLA supports engineering to define and develop the control architecture of CIS according to the stringent requirements of integrity, availability and response time. For functions with response times of the order of half a second is selected PLC High availability of industrial range. However, due to the nature of the machine itself, certain functions must be able to act under the millisecond, so it has had to develop a solution based on FPGA (Field Programmable Gate Array) capable of meeting the requirements architecture. In this article CIS architecture is described, as well as the process for the development and validation of the selected platforms. (Author)

Are Improvements in Cognitive Content and Depressive Symptoms Correlates or Mediators during Acute-Phase Cognitive Therapy for Recurrent Major Depressive Disorder?

Science.gov (United States)

Vittengl, Jeffrey R; Clark, Lee Anna; Thase, Michael E; Jarrett, Robin B

2014-01-09

The cognitive model of depression posits that cognitive therapy's (CT) effect on depressive symptoms is mediated by changes in cognitive content (e.g., automatic negative thoughts dysfunctional attitudes, failure attributions). We tested improvement and normalization of cognitive content among outpatients ( N = 523) with recurrent major depressive disorder treated with acute-phase CT (Jarrett & Thase, 2010; Jarrett et al., 2013). We also tested whether improvement in cognitive content accounted for subsequent changes in depressive symptoms and vice versa. Five measures of content improved substantively from pre- to post-CT (median d = 0.96), and the proportions of patients scoring in "healthy" ranges increased (median 45% to 82%). Evidence for cognitive mediation of symptom reduction was limited (median r = .06), as was evidence for symptom mediation of cognitive content improvement (median r = .07). We discuss measurement and design issues relevant to detection of mediators and consider alternative theories of change.

Interliminal Design: Understanding cognitive heuristics to mitigate design distortion

OpenAIRE

Andrew McCollough; DeAunne Denmark; Donald Harker

2014-01-01

Cognitive heuristics are mental shortcuts adapted over time to enable rapid interpretation of our complex environment. They are intrinsic to human cognition and resist modification. Heuristics applied outside the context to which they are best suited are termed cognitive bias, and are the cause of systematic errors in judgment and reasoning. As both a cognitive and intuitive discipline, design by individuals is vulnerable to context-inappropriate heuristic usage. Designing in groups can act p...

Cognitive, Heterogeneous and Reconfigurable Optical Networks: The CHRON Project

DEFF Research Database (Denmark)

Caballero Jambrina, Antonio; Borkowski, Robert; de Miguel, Ignacio

2014-01-01

. The incorporation of cognitive techniques can help to optimize a network by employing mechanisms that can observe, act, learn and improve network performance, taking into account end-to-end goals. The EU project CHRON: Cognitive Heterogeneous Reconfigurable Optical Network proposes a strategy to efficiently control...... the network by implementing cognition. In this paper we present a survey of different techniques developed throughout the course of the project to apply cognition in future optical networks....

Combined Cognitive-Psychological-Physical Intervention Induces Reorganization of Intrinsic Functional Brain Architecture in Older Adults

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Zhiwei Zheng

2015-01-01

Full Text Available Mounting evidence suggests that enriched mental, physical, and socially stimulating activities are beneficial for counteracting age-related decreases in brain function and cognition in older adults. Here, we used functional magnetic resonance imaging (fMRI to demonstrate the functional plasticity of brain activity in response to a combined cognitive-psychological-physical intervention and investigated the contribution of the intervention-related brain changes to individual performance in healthy older adults. The intervention was composed of a 6-week program of combined activities including cognitive training, Tai Chi exercise, and group counseling. The results showed improved cognitive performance and reorganized regional homogeneity of spontaneous fluctuations in the blood oxygen level-dependent (BOLD signals in the superior and middle temporal gyri, and the posterior lobe of the cerebellum, in the participants who attended the intervention. Intriguingly, the intervention-induced changes in the coherence of local spontaneous activity correlated with the improvements in individual cognitive performance. Taken together with our previous findings of enhanced resting-state functional connectivity between the medial prefrontal cortex and medial temporal lobe regions following a combined intervention program in older adults, we conclude that the functional plasticity of the aging brain is a rather complex process, and an effective cognitive-psychological-physical intervention is helpful for maintaining a healthy brain and comprehensive cognition during old age.

Architectural prototyping

DEFF Research Database (Denmark)

Bardram, Jakob Eyvind; Christensen, Henrik Bærbak; Hansen, Klaus Marius

2004-01-01

A major part of software architecture design is learning how specific architectural designs balance the concerns of stakeholders. We explore the notion of "architectural prototypes", correspondingly architectural prototyping, as a means of using executable prototypes to investigate stakeholders...

A simulation study of the effects of architectural constraints and resource translocation on population structure and competition in clonal plants

Czech Academy of Sciences Publication Activity Database

Herben, Tomáš; Suzuki, J. I.

2002-01-01

Roč. 15, - (2002), s. 403-423 ISSN 0269-7653 R&D Projects: GA ČR GA206/02/0953; GA MŠk ME 197 Institutional research plan: CEZ:AV0Z6005908 Keywords : architectural model * architectural rules * competitive ability Subject RIV: EF - Botanics Impact factor: 1.520, year: 2002

Research on the relationship between SPECT and cognitional potential of patients with cerebral infarction

International Nuclear Information System (INIS)

Zhao Heqing; Bao Shiyao; He Guangren

1995-01-01

The relationships among the regional cerebral blood flow (rCBF), the diaschisis and the change of cognitional potential in cerebral infarction are discussed. In 46 patients the ratio of rCBF was obtained by brain blood perfusion SPECT imaging. The cognitional potential was produced by evoking P300 wave with auditory Oddball model. The rCBF in infarct and its surrounding area decreased. The ratio of rCBF was less than 0.9. The detection of cognitional potential showed that the latency of P300 was delayed or negative. There was a significant correlation between the change of rCBF and the latency of P300 (r s = 0.876, P<0.001). The hypoperfusion of cerebral blood flow and diaschisis resulted in the cognitive impairment. There was a positive correlation between the cognitive impairment and the site and magnitude of decreased rCBF

La chapelle de la résidence universitaire Jean-Zay à Antony (Hauts-de-Seine par Eugène Beaudouin : matériau traditionnel de l’architecture religieuse et création contemporaine

Directory of Open Access Journals (Sweden)

Florence Margo-Schwoebel

2009-11-01

Full Text Available Après avoir mené à Antony la construction de la résidence universitaire Jean Zay en dix-huit mois (1954-1955, grâce à des procédés de construction industrialisés, Eugène Beaudouin compléta son projet d’une chapelle indépendante, réalisée selon des procédés traditionnels et consacrée en 1961. Dans cette chapelle Sainte-Croix, l’architecte renouait avec une certaine approche historiciste, sans pour autant rompre avec la création contemporaine. Son goût affirmé pour la prédominance du dessin s’y conjuguait à un jeu subtil sur la notion de « vérité du matériau », chère à l’architecture de la seconde moitié du XXe siècle. Mais le parti pris architectural semi-souterrain lui permettait surtout de développer un espace liturgique dramatisé, autour de la symbolique du baptême, en rapport direct avec les grands projets contemporains d’architecture religieuse.Using industrialised construction techniques, the architect Eugène Beaudouin was able to complete the building of the Jean Zay university residence, at Antony, in eighteen months, between 1954 and 1955. After completing this hall of residence, the architect then designed an independent chapel, built with traditional techniques and consecrated in 1961. In this Sainte-Croix chapel, Beaudouin renewed a certain historicist approach although he did not turn his back on contemporary creation. His pronounced taste for the predominance of design was associated with a subtle play on the notion of ‘the truth of the material’, one of the key architectural precepts of the second half of the 20th century. But the half-underground architecture also allowed him to create a dramatised liturgical space, around the symbolism of baptism and in relation to other contemporary projects in religious architecture.

Architectural freedom and industrialized architecture

DEFF Research Database (Denmark)

Vestergaard, Inge

2012-01-01

to explain that architecture can be thought as a complex and diverse design through customization, telling exactly the revitalized storey about the change to a contemporary sustainable and better performing expression in direct relation to the given context. Through the last couple of years we have...... proportions, to organize the process on site choosing either one room wall components or several rooms wall components – either horizontally or vertically. Combined with the seamless joint the playing with these possibilities the new industrialized architecture can deliver variations in choice of solutions...... for retrofit design. If we add the question of the installations e.g. ventilation to this systematic thinking of building technique we get a diverse and functional architecture, thereby creating a new and clearer story telling about new and smart system based thinking behind architectural expression....

Architectural freedom and industrialized architecture

DEFF Research Database (Denmark)

Vestergaard, Inge

2012-01-01

to explain that architecture can be thought as a complex and diverse design through customization, telling exactly the revitalized storey about the change to a contemporary sustainable and better performing expression in direct relation to the given context. Through the last couple of years we have...... expression in the specific housing area. It is the aim of this article to expand the different design strategies which architects can use – to give the individual project attitudes and designs with architectural quality. Through the customized component production it is possible to choose different...... for retrofit design. If we add the question of the installations e.g. ventilation to this systematic thinking of building technique we get a diverse and functional architecture, thereby creating a new and clearer story telling about new and smart system based thinking behind architectural expression....

Architectural freedom and industrialised architecture

DEFF Research Database (Denmark)

Vestergaard, Inge

2012-01-01

Architectural freedom and industrialized architecture. Inge Vestergaard, Associate Professor, Cand. Arch. Aarhus School of Architecture, Denmark Noerreport 20, 8000 Aarhus C Telephone +45 89 36 0000 E-mai l inge.vestergaard@aarch.dk Based on the repetitive architecture from the "building boom" 1960...... customization, telling exactly the revitalized storey about the change to a contemporary sustainable and better performed expression in direct relation to the given context. Through the last couple of years we have in Denmark been focusing a more sustainable and low energy building technique, which also include...... to the building physic problems a new industrialized period has started based on light weight elements basically made of wooden structures, faced with different suitable materials meant for individual expression for the specific housing area. It is the purpose of this article to widen up the different design...

Acute Kynurenine Challenge Disrupts Sleep-Wake Architecture and Impairs Contextual Memory in Adult Rats.

Science.gov (United States)

Pocivavsek, Ana; Baratta, Annalisa M; Mong, Jessica A; Viechweg, Shaun S

2017-11-01

Tryptophan metabolism via the kynurenine pathway may represent a key molecular link between sleep loss and cognitive dysfunction. Modest increases in the kynurenine pathway metabolite kynurenic acid (KYNA), which acts as an antagonist at N-methyl-d-aspartate and α7 nicotinic acetylcholine receptors in the brain, result in cognitive impairments. As glutamatergic and cholinergic neurotransmissions are critically involved in modulation of sleep, our current experiments tested the hypothesis that elevated KYNA adversely impacts sleep quality. Adult male Wistar rats were treated with vehicle (saline) and kynurenine (25, 50, 100, and 250 mg/kg), the direct bioprecursor of KYNA, intraperitoneally at zeitgeber time (ZT) 0 to rapidly increase brain KYNA. Levels of KYNA in the brainstem, cortex, and hippocampus were determined at ZT 0, ZT 2, and ZT 4, respectively. Analyses of vigilance state-related parameters categorized as wake, rapid eye movement (REM), and non-REM (NREM) as well as spectra power analysis during NREM and REM were assessed during the light phase. Separate animals were tested in the passive avoidance paradigm, testing contextual memory. When KYNA levels were elevated in the brain, total REM duration was reduced and total wake duration was increased. REM and wake architecture, assessed as number of vigilance state bouts and average duration of each bout, and theta power during REM were significantly impacted. Kynurenine challenge impaired performance in the hippocampal-dependent contextual memory task. Our results introduce kynurenine pathway metabolism and formation of KYNA as a novel molecular target contributing to sleep disruptions and cognitive impairments. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

Inter organizational System Management for integrated service delivery: an Enterprise Architecture Perspective

OpenAIRE

Elmir, Abir; Elmir, Badr; Bounabat, Bouchaib

2015-01-01

Service sharing is a prominent operating model to support business. Many large inter-organizational networks have implemented some form of value added integrated services in order to reach efficiency and to reduce costs sustainably. Coupling Service orientation with enterprise architecture paradigm is very important at improving organizational performance through business process optimization. Indeed, enterprise architecture management is increasingly discussed because of information system r...

Occupational Characteristics and Cognitive Aging in the Glostrup 1914 Cohort

DEFF Research Database (Denmark)

Gow, Alan J; Avlund, Kirsten; Mortensen, Erik L

2014-01-01

Objectives.The effect of occupational characteristics on cognitive change over 20 years was examined.Method.Occupational characteristics-intellectual challenge, physical hazards, and psychological demands-were assessed in the Glostrup 1914 Cohort when aged 60 years, and cognitive ability...... was assessed by 4 cognitive ability tests at ages 60, 70, and 80. RESULTS: Individuals in more intellectually challenging occupations had higher cognitive ability (r = .27-.38, p occupations performed more poorly (r = -.12 and -.13 at ages 50 and 60, p ..., the one in the more intellectually challenging occupation had lower subsequent cognitive ability. The association of physical hazards with lower cognitive ability level did not remain after adjustment for the basic demographics, and none of the occupational characteristics were associated with cognitive...

Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging

Science.gov (United States)

Park, Seok-Joo; Shin, Eun-Joo; Min, Sun Seek; An, Jihua; Li, Zhengyi; Hee Chung, Yoon; Hoon Jeong, Ji; Bach, Jae-Hyung; Nah, Seung-Yeol; Kim, Won-Ki; Jang, Choon-Gon; Kim, Yong-Sun; Nabeshima, Yo-ichi; Nabeshima, Toshitaka; Kim, Hyoung-Chun

2013-01-01

We previously reported cognitive dysfunction in klotho mutant mice. In the present study, we further examined novel mechanisms involved in cognitive impairment in these mice. Significantly decreased janus kinase 2 (JAK2) and signal transducer and activator of transcription3 (STAT3) phosphorylation were observed in the hippocampus of klotho mutant mice. A selective decrease in protein expression and binding density of the M1 muscarinic cholinergic receptor (M1 mAChR) was observed in these mice. Cholinergic parameters (ie, acetylcholine (ACh), choline acetyltransferase (ChAT), and acetylcholinesterase (AChE)) and NMDAR-dependent long-term potentiation (LTP) were significantly impaired in klotho mutant mice. McN-A-343 (McN), an M1 mAChR agonist, significantly attenuated these impairments. AG490 (AG), a JAK2 inhibitor, counteracted the attenuating effects of McN, although AG did not significantly alter the McN-induced effect on AChE. Furthermore, AG significantly inhibited the attenuating effects of McN on decreased NMDAR-dependent LTP, protein kinase C βII, p-ERK, p-CREB, BDNF, and p-JAK2/p-STAT3-expression in klotho mutant mice. In addition, k252a, a BDNF receptor tyrosine kinase B (TrkB) inhibitor, significantly counteracted McN effects on decreased ChAT, ACh, and M1 mAChR and p-JAK2/p-STAT3 expression. McN-induced effects on cognitive impairment in klotho mutant mice were consistently counteracted by either AG or k252a. Our results suggest that inactivation of the JAK2/STAT3 signaling axis and M1 mAChR downregulation play a critical role in cognitive impairment observed in klotho mutant mice. PMID:23389690

Learning, epigenetics, and computation: An extension on Fitch's proposal. Comment on “Toward a computational framework for cognitive biology: Unifying approaches from cognitive neuroscience and comparative cognition” by W. Tecumseh Fitch

Science.gov (United States)

Okanoya, Kazuo

2014-09-01

The comparative computational approach of Fitch [1] attempts to renew the classical David Marr paradigm of computation, algorithm, and implementation, by introducing evolutionary view of the relationship between neural architecture and cognition. This comparative evolutionary view provides constraints useful in narrowing down the problem space for both cognition and neural mechanisms. I will provide two examples from our own studies that reinforce and extend Fitch's proposal.

Categorial compositionality II: universal constructions and a general theory of (quasi-systematicity in human cognition.

Directory of Open Access Journals (Sweden)

Steven Phillips

2011-08-01

Full Text Available A complete theory of cognitive architecture (i.e., the basic processes and modes of composition that together constitute cognitive behaviour must explain the systematicity property--why our cognitive capacities are organized into particular groups of capacities, rather than some other, arbitrary collection. The classical account supposes: (1 syntactically compositional representations; and (2 processes that are sensitive to--compatible with--their structure. Classical compositionality, however, does not explain why these two components must be compatible; they are only compatible by the ad hoc assumption (convention of employing the same mode of (concatenative compositionality (e.g., prefix/postfix, where a relation symbol is always prepended/appended to the symbols for the related entities. Architectures employing mixed modes do not support systematicity. Recently, we proposed an alternative explanation without ad hoc assumptions, using category theory. Here, we extend our explanation to domains that are quasi-systematic (e.g., aspects of most languages, where the domain includes some but not all possible combinations of constituents. The central category-theoretic construct is an adjunction involving pullbacks, where the primary focus is on the relationship between processes modelled as functors, rather than the representations. A functor is a structure-preserving map (or construction, for our purposes. An adjunction guarantees that the only pairings of functors are the systematic ones. Thus, (quasi-systematicity is a necessary consequence of a categorial cognitive architecture whose basic processes are functors that participate in adjunctions.

Categorial compositionality II: universal constructions and a general theory of (quasi-)systematicity in human cognition.

Science.gov (United States)

Phillips, Steven; Wilson, William H

2011-08-01

A complete theory of cognitive architecture (i.e., the basic processes and modes of composition that together constitute cognitive behaviour) must explain the systematicity property--why our cognitive capacities are organized into particular groups of capacities, rather than some other, arbitrary collection. The classical account supposes: (1) syntactically compositional representations; and (2) processes that are sensitive to--compatible with--their structure. Classical compositionality, however, does not explain why these two components must be compatible; they are only compatible by the ad hoc assumption (convention) of employing the same mode of (concatenative) compositionality (e.g., prefix/postfix, where a relation symbol is always prepended/appended to the symbols for the related entities). Architectures employing mixed modes do not support systematicity. Recently, we proposed an alternative explanation without ad hoc assumptions, using category theory. Here, we extend our explanation to domains that are quasi-systematic (e.g., aspects of most languages), where the domain includes some but not all possible combinations of constituents. The central category-theoretic construct is an adjunction involving pullbacks, where the primary focus is on the relationship between processes modelled as functors, rather than the representations. A functor is a structure-preserving map (or construction, for our purposes). An adjunction guarantees that the only pairings of functors are the systematic ones. Thus, (quasi-)systematicity is a necessary consequence of a categorial cognitive architecture whose basic processes are functors that participate in adjunctions.

Enterprise architecture evaluation using architecture framework and UML stereotypes

Directory of Open Access Journals (Sweden)

Narges Shahi

2014-08-01

Full Text Available There is an increasing need for enterprise architecture in numerous organizations with complicated systems with various processes. Support for information technology, organizational units whose elements maintain complex relationships increases. Enterprise architecture is so effective that its non-use in organizations is regarded as their institutional inability in efficient information technology management. The enterprise architecture process generally consists of three phases including strategic programing of information technology, enterprise architecture programing and enterprise architecture implementation. Each phase must be implemented sequentially and one single flaw in each phase may result in a flaw in the whole architecture and, consequently, in extra costs and time. If a model is mapped for the issue and then it is evaluated before enterprise architecture implementation in the second phase, the possible flaws in implementation process are prevented. In this study, the processes of enterprise architecture are illustrated through UML diagrams, and the architecture is evaluated in programming phase through transforming the UML diagrams to Petri nets. The results indicate that the high costs of the implementation phase will be reduced.

Utility and limitations of Addenbrooke's Cognitive Examination-Revised for detecting mild cognitive impairment in Parkinson's disease.

Science.gov (United States)

Komadina, Natalie C; Terpening, Zoe; Huang, Yue; Halliday, Glenda M; Naismith, Sharon L; Lewis, Simon J G

2011-01-01

To evaluate the utility of the Addenbrooke's Cognitive Examination-Revised (ACE-R) as a screening tool for mild cognitive impairment in Parkinson's disease (PD-MCI). PD patients underwent comprehensive neuropsychological and neurological evaluations and ACE-R assessment. The ACE-R was superior to the Mini-Mental State Exam (MMSE) in detecting PD-MCI, with a cutoff score of ≤93 offering a sensitivity of 61% and a specificity of 64%. The utility of the ACE-R in detecting PD-MCI is largely influenced by the fluency sub-domain score, and has optimal discriminability when utilized in patients with lower levels of education (≤12 years of formal schooling). The ACE-R must be used cautiously as a screening tool for PD-MCI, with results being most influenced by its fluency sub-domain score and patient education levels. Copyright © 2011 S. Karger AG, Basel.

Effects of Aerobic Training on Cognition and Brain Glucose Metabolism in Subjects with Mild Cognitive Impairment.

Science.gov (United States)

Porto, Fábio Henrique de Gobbi; Coutinho, Artur Martins Novaes; Pinto, Ana Lucia de Sá; Gualano, Bruno; Duran, Fabio Luís de Souza; Prando, Silvana; Ono, Carla Rachel; Spíndola, Lívia; de Oliveira, Maira Okada; do Vale, Patrícia Helena Figuerêdo; Nitrini, Ricardo; Buchpiguel, Carlos Alberto; Brucki, Sonia Maria Dozzi

2015-01-01

Aerobic training (AT) is a promising intervention for mild cognitive impairment (MCI). To evaluate the effects of AT on cognition and regional brain glucose metabolism (rBGM) in MCI patients. Subjects performed a twice-a-week, moderate intensity, AT program for 24 weeks. Assessment with ADAS-cog, a comprehensive neuropsychological battery, and evaluation of rBGM with positron emission tomography with 18F-fluorodeoxyglucose ([18F]FDG-PET) were performed before and after the intervention. Aerobic capacity was compared using the maximal oxygen consumption VO2max (mL/Kg/min). [18F]FDG-PET data were analyzed on a voxel-by-voxel basis with SPM8 software. Forty subjects were included, with a mean (M) age of 70.3 (5.4) years and an initial Mini-Mental State Exam score of 27.4 (1.7). Comparisons using paired t-tests revealed improvements in the ADAS-cog (M difference: -2.7 (3.7), p <  0.001) and VO2max scores (M difference: 1.8 (2.0) mL/kg/min, p <  0.001). Brain metabolic analysis revealed a bilateral decrease in the rBGM of the dorsal anterior cingulate cortex, pFWE = 0.04. This rBGM decrease was negatively correlated with improvement in a visuospatial function/attentional test (rho =-0.31, p = 0.04). Several other brain areas also showed increases or decreases in rBGM. Of note, there was an increase in the retrosplenial cortex, an important node of the default mode network, that was negatively correlated with the metabolic decrease in the dorsal anterior cingulate cortex (r =-0.51, p = 0.001). AT improved cognition and changed rBGM in areas related to cognition in subjects with MCI.

77 FR 65939 - Privacy Act of 1974; System of Records

Science.gov (United States)

2012-10-31

...) is amending the system of records currently entitled ``Veterans Health Information Systems and... Health Information Systems and Technology Architecture (VistA) Records-VA ROUTINE USES OF RECORDS... DEPARTMENT OF VETERANS AFFAIRS Privacy Act of 1974; System of Records AGENCY: Department of...

Software architecture 2

CERN Document Server

Oussalah, Mourad Chabanne

2014-01-01

Over the past 20 years, software architectures have significantly contributed to the development of complex and distributed systems. Nowadays, it is recognized that one of the critical problems in the design and development of any complex software system is its architecture, i.e. the organization of its architectural elements. Software Architecture presents the software architecture paradigms based on objects, components, services and models, as well as the various architectural techniques and methods, the analysis of architectural qualities, models of representation of architectural templa

Lightweight enterprise architectures

CERN Document Server

Theuerkorn, Fenix

2004-01-01

STATE OF ARCHITECTUREArchitectural ChaosRelation of Technology and Architecture The Many Faces of Architecture The Scope of Enterprise Architecture The Need for Enterprise ArchitectureThe History of Architecture The Current Environment Standardization Barriers The Need for Lightweight Architecture in the EnterpriseThe Cost of TechnologyThe Benefits of Enterprise Architecture The Domains of Architecture The Gap between Business and ITWhere Does LEA Fit? LEA's FrameworkFrameworks, Methodologies, and Approaches The Framework of LEATypes of Methodologies Types of ApproachesActual System Environmen

Software architecture 1

CERN Document Server

Oussalah , Mourad Chabane

2014-01-01

Over the past 20 years, software architectures have significantly contributed to the development of complex and distributed systems. Nowadays, it is recognized that one of the critical problems in the design and development of any complex software system is its architecture, i.e. the organization of its architectural elements. Software Architecture presents the software architecture paradigms based on objects, components, services and models, as well as the various architectural techniques and methods, the analysis of architectural qualities, models of representation of architectural template

Reduced-Complexity Wireless Transceiver Architectures and Techniques for Space-Time Communications

DEFF Research Database (Denmark)

Tsakalaki, Elpiniki

2012-01-01

The dissertation sheds light on the performance gains of multi-antenna systems when the antenna aspects and the associated signal processing and coding aspects are integrated together in a multidisciplinary approach, addressing a variety of challenging tasks pertaining to the joint design of smart...... wireless transceivers and communication techniques. These tasks are at the intersection of different scientific disciplines including signal processing, communications, antennas and propagation. Specifically, the thesis deals with reduced-complexity space-time wireless transceiver architectures...... and associated communication techniques for multi-input multi-output (MIMO) and cognitive radio (CR) systems as well as wireless sensor networks (WSNs). The low-complexity architectures are obtained by equipping the wireless transceiver with passive control ports which require the minimum amount of RF hardware...

Indigenous architecture as a context-oriented architecture, a look at ...

African Journals Online (AJOL)

What has become problematic as the achievement of international style and globalization of architecture during the time has been the purely technological look at architecture, and the architecture without belonging to a place. In recent decades, the topic of sustainable architecture and reconsidering indigenous architecture ...

Modeling Environmental Impacts on Cognitive Performance for Artificially Intelligent Entities

Science.gov (United States)

2017-06-01

Mavor, 1998). It should be noted that the authors mention the military user audience as a key constituent that must be able to trust the validity...modeling efforts in cognitive architectures. Ultimately, the Task Group 128 report finds that “modeling of post- receptive perceptual processes such

Cognitive predictors of everyday functioning in older adults: results from the ACTIVE Cognitive Intervention Trial.

Science.gov (United States)

Gross, Alden L; Rebok, George W; Unverzagt, Frederick W; Willis, Sherry L; Brandt, Jason

2011-09-01

The present study sought to predict changes in everyday functioning using cognitive tests. Data from the Advanced Cognitive Training for Independent and Vital Elderly trial were used to examine the extent to which competence in different cognitive domains--memory, inductive reasoning, processing speed, and global mental status--predicts prospectively measured everyday functioning among older adults. Coefficients of determination for baseline levels and trajectories of everyday functioning were estimated using parallel process latent growth models. Each cognitive domain independently predicts a significant proportion of the variance in baseline and trajectory change of everyday functioning, with inductive reasoning explaining the most variance (R2 = .175) in baseline functioning and memory explaining the most variance (R2 = .057) in changes in everyday functioning. Inductive reasoning is an important determinant of current everyday functioning in community-dwelling older adults, suggesting that successful performance in daily tasks is critically dependent on executive cognitive function. On the other hand, baseline memory function is more important in determining change over time in everyday functioning, suggesting that some participants with low baseline memory function may reflect a subgroup with incipient progressive neurologic disease.

Compartmentalization in hybrid metallacarborane nanoparticles formed by block copolymers with star-like architecture

Czech Academy of Sciences Publication Activity Database

Ďorďovič, V.; Uchman, M.; Zhigunov, Alexander; Nykänen, A.; Ruokolainen, J.; Matějíček, P.

2014-01-01

Roč. 3, č. 11 (2014), s. 1151-1155 ISSN 2161-1653 R&D Projects: GA ČR(CZ) GA14-14608S Institutional support: RVO:61389013 Keywords : nanoparticles * block copolymers * star-like architecture Subject RIV: CD - Macromolecular Chemistry Impact factor: 5.764, year: 2014

A cog in cognition: how the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits.

Science.gov (United States)

Leiser, Steven C; Bowlby, Mark R; Comery, Thomas A; Dunlop, John

2009-06-01

Cognition, memory, and attention and arousal have been linked to nicotinic acetylcholine receptors (nAChRs). Thus it is not surprising that nAChRs have been strongly implicated as therapeutic targets for treating cognitive deficits in disorders such as schizophrenia and Alzheimer's disease (AD). In particular the alpha7 (alpha7) nAChR has been closely linked with normalization of P50 auditory evoked potential (AEP) gating deficits, and to a lesser extent improvements in pre-pulse inhibition (PPI) of the acoustic startle response. These two brain phenomena can be considered as pre-attentive, occurring while sensory information is being processed, and are important endophenotypes in schizophrenia with deficits likely contributing to the cognitive fragmentation associated with the disease. In addition alpha7 nAChRs have been implicated in attention, in particular under high attentional demand, and in more demanding working memory tasks such as long delays in delayed matching tasks. Efficacy of alpha7 nAChR agonists across a range of cognitive processes ranging from pre-attentive to attentive states and working and recognition memory provides a solid basis for their pro-cognitive effects. This review will focus on the recent work highlighting the role of alpha7 in cognition and cognitive processes.

Nouvelle architecture électromagnétique à réluctance variable excitée pour accumulateur électromécanique d'énergie

OpenAIRE

Gergaud , Olivier; BEN AHMED , Hamid; Multon , Bernard; Bernard , Nicolas

2001-01-01

International audience; Cet article traite d'un moteur-générateur original destiné au stockage électromécanique d'énergie. Il est de type synchrone à excitation homopolaire fixe, à bobinage d'induit dans l'entrefer et d'architecture discoïde pour une meilleure intégration au volant d'inertie. Il ne doit pas perturber les suspensions magnétiques du dispositif, pour cela nous avons mené une étude détaillée des efforts magnétiques, notamment parasites, générés dans cette structure. Une méthode p...

Green collaboration in cognitive radio cellular networks with roaming and spectrum trading

KAUST Repository

Sboui, Lokman; Ghazzai, Hakim; Rezki, Zouheir; Alouini, Mohamed-Slim

2015-01-01

In this paper, we propose a new cognitive cellular network architecture based on the coexistence of primary and secondary networks, (PN) and (SN), respectively. The PN aims to minimize its energy consumption by switching off the maximum number

Cognitive fatigue in patients with myasthenia gravis.

Science.gov (United States)

Jordan, Berit; Schweden, Tabea L K; Mehl, Theresa; Menge, Uwe; Zierz, Stephan

2017-09-01

Cognitive fatigue has frequently been reported in myasthenia gravis (MG). However, objective assessment of cognitive fatigability has never been evaluated. Thirty-three MG patients with stable generalized disease and 17 healthy controls underwent a test battery including repeated testing of attention and concentration (d2-R) and Paced Auditory Serial Addition Test. Fatigability was based on calculation of linear trend (LT) reflecting dynamic performance within subsequent constant time intervals. Additionally, fatigue questionnaires were used. MG patients showed a negative LT in second d2-R testing, indicating cognitive fatigability. This finding significantly differed from stable cognitive performance in controls (P fatigue was significantly higher in MG patients compared with controls (P fatigue is not correlated with objective findings. Muscle Nerve 56: 449-457, 2017. © 2016 Wiley Periodicals, Inc.

Architecture in the Islamic Civilization: Muslim Building or Islamic Architecture

OpenAIRE

Yassin, Ayat Ali; Utaberta, Dr. Nangkula

2012-01-01

The main problem of the theory in the arena of islamic architecture is affected by some of its Westernthoughts, and stereotyping the islamic architecture according to Western thoughts; this leads to the breakdownof the foundations in the islamic architecture. It is a myth that islamic architecture is subjected to theinfluence from foreign architectures. This paper will highlight the dialectical concept of islamic architecture ormuslim buildings and the areas of recognition in islamic architec...

Does the cognitive architecture of simplex and multiplex ASD families differ?

NARCIS (Netherlands)

Oerlemans, Anoek M.; Hartman, Catharina A.; Franke, Barbara; Buitelaar, Jan K.; Rommelse, Nanda N. J.

Children with an autism spectrum disorder (ASD) and their unaffected siblings from 54 simplex (SPX, one individual in the family affected) and 59 multiplex (MPX, two or more individuals affected) families, and 124 controls were assessed on intelligence, social cognition and executive functions. SPX

Does the cognitive architecture of simplex and multiplex ASD families differ?

NARCIS (Netherlands)

Oerlemans, A.M.; Hartman, C.A.; Franke, B.; Buitelaar, J.K.; Rommelse, N.N.J.

2016-01-01

Children with an autism spectrum disorder (ASD) and their unaffected siblings from 54 simplex (SPX, one individual in the family affected) and 59 multiplex (MPX, two or more individuals affected) families, and 124 controls were assessed on intelligence, social cognition and executive functions. SPX

Motivation for Creativity in Architectural Design and Engineering Design Students: Implications for Design Education

Science.gov (United States)

Casakin, Hernan; Kreitler, Shulamith

2010-01-01

The investigation reported here dealt with the study of motivation for creativity. The goals were to assess motivation for creativity in architectural design and engineering design students based on the Cognitive Orientation theory which defines motivation as a function of a set of belief types, themes, and groupings identified as relevant for the…

Metrics of brain network architecture capture the impact of disease in children with epilepsy

Directory of Open Access Journals (Sweden)

Michael J. Paldino

2017-01-01

Conclusions: We observed that a machine learning algorithm accurately predicted epilepsy duration based on global metrics of network architecture derived from resting state fMRI. These findings suggest that network metrics have the potential to form the basis for statistical models that translate quantitative imaging data into patient-level markers of cognitive deterioration.

Effects of Motion in the Far Peripheral Visual Field on Cognitive Test Performance and Cognitive Load.

Science.gov (United States)

Bevilacqua, Andy; Paas, Fred; Krigbaum, Genomary

2016-04-01

Cognitive load theory posits that limited attention is in actuality a limitation in working memory resources. The load theory of selective attention and cognitive control sees the interplay between attention and awareness as separate modifying functions that act on working memory. Reconciling the theoretical differences in these two theories has important implications for learning. Thirty-nine adult participants performed a cognitively demanding test, with and without movement in the far peripheral field. Although the results for movement effects on cognitive load in this experiment were not statistically significant, men spent less time on the cognitive test in the peripheral movement condition than in the conditions without peripheral movement. No such difference was found for women. The implications of these results and recommendations for future research that extends the present study are presented. © The Author(s) 2016.

A unified architecture of transcriptional regulatory elements

DEFF Research Database (Denmark)

Andersson, Robin; Sandelin, Albin Gustav; Danko, Charles G.

2015-01-01

Gene expression is precisely controlled in time and space through the integration of signals that act at gene promoters and gene-distal enhancers. Classically, promoters and enhancers are considered separate classes of regulatory elements, often distinguished by histone modifications. However...... and enhancers are considered a single class of functional element, with a unified architecture for transcription initiation. The context of interacting regulatory elements and the surrounding sequences determine local transcriptional output as well as the enhancer and promoter activities of individual elements....

miR-598 acts as a tumor suppressor in human gastric cancer by targeting IGF-1R.

Science.gov (United States)

Liu, Na; Yang, Hua; Wang, Hong

2018-01-01

In recent years, the aberrant expression of miR-598 in tumorigenesis has been demonstrated, as well as the fact that the IGF-1R pathway is also involved in the development of human gastric cancer (GC). The present study aimed to investigate the molecular mechanisms underlying miR-598-regulated IGF-1R expression in human GC. We analyzed the expression of miR-598 and IGF-1R in GC samples and cells, and evaluated the clinical significance of miR-598 and IGF-1R in GC patients. Furthermore, in vitro and in vivo assays were used to investigate the molecular mechanisms of miR-598 and IGF-1R. miR-598 expression was frequently downregulated in GC tissues and cells, and significantly correlated with poor prognosis, vascular invasion, TNM stage, and lymph node metastases as well as IGF-1R expression. The overexpression of miR-598 obviously inhibited cell proliferation, migration, invasion, and induced cell cycle arrest in the G1/S phase, and increased the apoptosis of GC cells. The overexpression of miR-598 also significantly inhibited ERK1/2 and Akt phosphorylation level. In vivo assay validated the inhibitory effect of miR-598 on tumor growth. Further studies showed that miR-598 inhibited IGF-1R protein expression by directly targeting its 3'-UTR. Besides, over-expression of IGF-1R reversed the inhibitory effects of miR-598, while suppression of IGF-1R expression showed inverse effects. miR-598 suppresses GC cell proliferation, migration and invasion by directly targeting IGF-1R expression. Thus, miR-598 may be a useful target for GC patients.

Cognitive consilience: Primate non-primary neuroanatomical circuits underlying cognition

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Soren Van Hout Solari

2011-12-01

Full Text Available Interactions between the cerebral cortex, thalamus, and basal ganglia form the basis ofcognitive information processing in the mammalian brain. Understanding the principles ofneuroanatomical organization in these structures is critical to understanding the functions theyperform and ultimately how the human brain works. We have manually distilled and synthesizedhundreds of primate neuroanatomy facts into a single interactive visualization. The resultingpicture represents the fundamental neuroanatomical blueprint upon which cognitive functionsmust be implemented. Within this framework we hypothesize and detail 7 functional circuitscorresponding to psychological perspectives on the brain: consolidated long-term declarativememory, short-term declarative memory, working memory/information processing, behavioralmemory selection, behavioral memory output, cognitive control, and cortical information flow regulation. Each circuit is described in terms of distinguishable neuronal groups including thecerebral isocortex (9 pyramidal neuronal groups, parahippocampal gyrus and hippocampus,thalamus (4 neuronal groups, basal ganglia (7 neuronal groups, metencephalon, basal forebrainand other subcortical nuclei. We focus on neuroanatomy related to primate non-primary corticalsystems to elucidate the basis underlying the distinct homotypical cognitive architecture. To dis-play the breadth of this review, we introduce a novel method of integrating and presenting datain multiple independent visualizations: an interactive website (www.cognitiveconsilience.comand standalone iPhone and iPad applications. With these tools we present a unique, annotatedview of neuroanatomical consilience (integration of knowledge.

Association of Cognitive and Noncognitive Symptoms of Delirium: A Study from Consultation-liaison Psychiatry Set-up.

Science.gov (United States)

Grover, Sandeep; Mehra, Aseem; Chakrabarti, Subho; Avasthi, Ajit

2016-12-01

This study aims to evaluate the cognitive functions of patients with delirium using Hindi Mental Status Examination (HMSE), to study the correlation of cognitive functions assessed by HMSE with noncognitive symptoms as assessed using Delirium Rating Scale-Revised 1998 (DRS-R-98) and to study the association of cognitive functions assessed using HMSE and DRS-R98. A total of 76 consecutive patients fulfilling the diagnosis of delirium were evaluated on DRS-R-98, HMSE, and Short Informant Questionnaire on Cognitive Decline in the Elderly (retrospective IQCODE). The mean DRS-R-98 score 33.9 (standard deviation [SD] - 7.2) and the mean DRS-R-98 severity score was 25.9 (SD - 7.2). The mean score on HMSE was 19.3 (7.98). There were significant correlations of all the domains of HMSE with DRS-R-98 total score, DRS-R-98 severity score, DRS-R-98 cognitive subscale score, DRS-R-98 noncognitive domain subscale score, and DRS severity score without attention score. When the association of each item of DRS-R-98 and HMSE was evaluated, except for the items of delusions, lability of affect and motor retardation, there were significant negative association between all the items of DRS-R-98 and HMSE, indicating that higher severity of cognitive symptoms as assessed on HMSE is associated with higher severity of all the cognitive symptoms and most of the noncognitive symptoms as assessed by DRS-R-98. The present study suggests that attention deficits in patients with delirium influence the severity of cognitive and noncognitive symptoms of delirium. Further, the present study suggests an increase in the severity of cognitive symptoms in other domains is also associated with an increase in the severity of noncognitive symptoms of delirium.

A CSP-Based Agent Modeling Framework for the Cougaar Agent-Based Architecture

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Gracanin, Denis; Singh, H. Lally; Eltoweissy, Mohamed; Hinchey, Michael G.; Bohner, Shawn A.

2005-01-01

Cognitive Agent Architecture (Cougaar) is a Java-based architecture for large-scale distributed agent-based applications. A Cougaar agent is an autonomous software entity with behaviors that represent a real-world entity (e.g., a business process). A Cougaar-based Model Driven Architecture approach, currently under development, uses a description of system's functionality (requirements) to automatically implement the system in Cougaar. The Communicating Sequential Processes (CSP) formalism is used for the formal validation of the generated system. Two main agent components, a blackboard and a plugin, are modeled as CSP processes. A set of channels represents communications between the blackboard and individual plugins. The blackboard is represented as a CSP process that communicates with every agent in the collection. The developed CSP-based Cougaar modeling framework provides a starting point for a more complete formal verification of the automatically generated Cougaar code. Currently it is used to verify the behavior of an individual agent in terms of CSP properties and to analyze the corresponding Cougaar society.

Rational adaptation under task and processing constraints: implications for testing theories of cognition and action.

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Howes, Andrew; Lewis, Richard L; Vera, Alonso

2009-10-01

The authors assume that individuals adapt rationally to a utility function given constraints imposed by their cognitive architecture and the local task environment. This assumption underlies a new approach to modeling and understanding cognition-cognitively bounded rational analysis-that sharpens the predictive acuity of general, integrated theories of cognition and action. Such theories provide the necessary computational means to explain the flexible nature of human behavior but in doing so introduce extreme degrees of freedom in accounting for data. The new approach narrows the space of predicted behaviors through analysis of the payoff achieved by alternative strategies, rather than through fitting strategies and theoretical parameters to data. It extends and complements established approaches, including computational cognitive architectures, rational analysis, optimal motor control, bounded rationality, and signal detection theory. The authors illustrate the approach with a reanalysis of an existing account of psychological refractory period (PRP) dual-task performance and the development and analysis of a new theory of ordered dual-task responses. These analyses yield several novel results, including a new understanding of the role of strategic variation in existing accounts of PRP and the first predictive, quantitative account showing how the details of ordered dual-task phenomena emerge from the rational control of a cognitive system subject to the combined constraints of internal variance, motor interference, and a response selection bottleneck.

Augmented reality & gesture-based architecture in games for the elderly.

Science.gov (United States)

McCallum, Simon; Boletsis, Costas

2013-01-01

Serious games for health and, more specifically, for elderly people have developed rapidly in recent years. The recent popularization of novel interaction methods of consoles, such as the Nintendo Wii and Microsoft Kinect, has provided an opportunity for the elderly to engage in computer and video games. These interaction methods, however, still present various challenges for elderly users. To address these challenges, we propose an architecture consisted of Augmented Reality (as an output mechanism) combined with gestured-based devices (as an input method). The intention of this work is to provide a theoretical justification for using these technologies and to integrate them into an architecture, acting as a basis for potentially creating suitable interaction techniques for the elderly players.

Walking through Architectural Spaces: The Impact of Interior Forms on Human Brain Dynamics.

Science.gov (United States)

Banaei, Maryam; Hatami, Javad; Yazdanfar, Abbas; Gramann, Klaus

2017-01-01

Neuroarchitecture uses neuroscientific tools to better understand architectural design and its impact on human perception and subjective experience. The form or shape of the built environment is fundamental to architectural design, but not many studies have shown the impact of different forms on the inhabitants' emotions. This study investigated the neurophysiological correlates of different interior forms on the perceivers' affective state and the accompanying brain activity. To understand the impact of naturalistic three-dimensional (3D) architectural forms, it is essential to perceive forms from different perspectives. We computed clusters of form features extracted from pictures of residential interiors and constructed exemplary 3D room models based on and representing different formal clusters. To investigate human brain activity during 3D perception of architectural spaces, we used a mobile brain/body imaging (MoBI) approach recording the electroencephalogram (EEG) of participants while they naturally walk through different interior forms in virtual reality (VR). The results revealed a strong impact of curvature geometries on activity in the anterior cingulate cortex (ACC). Theta band activity in ACC correlated with specific feature types ( r s (14) = 0.525, p = 0.037) and geometry ( r s (14) = -0.579, p = 0.019), providing evidence for a role of this structure in processing architectural features beyond their emotional impact. The posterior cingulate cortex and the occipital lobe were involved in the perception of different room perspectives during the stroll through the rooms. This study sheds new light on the use of mobile EEG and VR in architectural studies and provides the opportunity to study human brain dynamics in participants that actively explore and realistically experience architectural spaces.

Toward cognitive robotics

Science.gov (United States)

Laird, John E.

2009-05-01

Our long-term goal is to develop autonomous robotic systems that have the cognitive abilities of humans, including communication, coordination, adapting to novel situations, and learning through experience. Our approach rests on the recent integration of the Soar cognitive architecture with both virtual and physical robotic systems. Soar has been used to develop a wide variety of knowledge-rich agents for complex virtual environments, including distributed training environments and interactive computer games. For development and testing in robotic virtual environments, Soar interfaces to a variety of robotic simulators and a simple mobile robot. We have recently made significant extensions to Soar that add new memories and new non-symbolic reasoning to Soar's original symbolic processing, which should significantly improve Soar abilities for control of robots. These extensions include episodic memory, semantic memory, reinforcement learning, and mental imagery. Episodic memory and semantic memory support the learning and recalling of prior events and situations as well as facts about the world. Reinforcement learning provides the ability of the system to tune its procedural knowledge - knowledge about how to do things. Mental imagery supports the use of diagrammatic and visual representations that are critical to support spatial reasoning. We speculate on the future of unmanned systems and the need for cognitive robotics to support dynamic instruction and taskability.

Screening of cognitive impairment in patients with Parkinson's disease: diagnostic validity of the Brazilian versions of the Montreal Cognitive Assessment and the Addenbrooke's Cognitive Examination-Revised

OpenAIRE

Emmanuelle Sobreira; Márcio A. Pena-Pereira; Alan L. Eckeli; Manoel A. Sobreira-Neto; Marcos H. N. Chagas; Maria P. Foss; Brenna Cholerton; Cyrus P. Zabetian; Ignacio F. Mata; Vitor Tumas

2015-01-01

ABSTRACTObjective The aim of the present study is to examine the accuracy of the Brazilian versions of the Montreal Cognitive Assessment (MoCA) and the Addenbrooke's Cognitive Examination-Revised (ACE-R) to screen for mild cognitive impairment (PDMCI) and dementia (PDD) in patients with Parkinson's disease (PD).Method Both scales were administered to a final convenience sample of 79 patients with PD. Patients were evaluated by a neurologist, a psychiatrist and a neuropsychologist using UPDRS,...

The impact of motivation on cognitive performance in an animal model of the negative and cognitive symptoms of schizophrenia.

Science.gov (United States)

Ward, Ryan D; Winiger, Vanessa; Higa, Kerin K; Kahn, Julia B; Kandel, Eric R; Balsam, Peter D; Simpson, Eleanor H

2015-06-01

Interactions between motivation and cognition are implicated in producing functional impairments and poor quality of life in psychiatric patients. This interaction, however, is not well understood at either the behavioral or neural level. We developed a procedure for mice in which a cognitive measure, sustained attention, is modulated by a motivationally relevant signal that predicts reward probability on a trial-by-trial basis. Using this paradigm, we tested the interaction between motivation and cognition in mice that model the increased striatal D2 receptor activity observed in schizophrenia patients (D2R-OE mice). In control mice, attention was modulated by signaled-reward probability. In D2R-OE mice, however, attention was not modulated by reward-related cues. This impairment was not due to any global deficits in attention or maintenance of the trial-specific information in working memory. Turning off the transgene in D2R-OE mice rescued the motivational modulation of attention. These results indicate that deficits in motivation impair the ability to use reward-related cues to recruit attention and that improving motivation improves functional cognitive performance. These results further suggest that addressing motivational impairments in patients is critical to achieving substantive cognitive and functional gains. (c) 2015 APA, all rights reserved).

Cognitive-behavioral therapy (CBT) versus acceptance and commitment therapy (ACT) for dementia family caregivers with significant depressive symptoms: Results of a randomized clinical trial.

Science.gov (United States)

Losada, Andrés; Márquez-González, María; Romero-Moreno, Rosa; Mausbach, Brent T; López, Javier; Fernández-Fernández, Virginia; Nogales-González, Celia

2015-08-01

The differential efficacy of acceptance and commitment therapy (ACT) and cognitive-behavioral therapy (CBT) for dementia family caregivers' is analyzed through a randomized controlled trial. Participants were 135 caregivers with high depressive symptomatology who were randomly allocated to the intervention conditions or a control group (CG). Pre-, postintervention, and follow-up measurements assessed depressive symptomatology, anxiety, leisure, dysfunctional thoughts, and experiential avoidance. Depression: Significant effects of interventions compared with CG were found for CBT (p dementia caregivers. (c) 2015 APA, all rights reserved).

Cognitive function affects trainability for physical performance in exercise intervention among older adults with mild cognitive impairment.

Science.gov (United States)

Uemura, Kazuki; Shimada, Hiroyuki; Makizako, Hyuma; Doi, Takehiko; Yoshida, Daisuke; Tsutsumimoto, Kota; Anan, Yuya; Suzuki, Takao

2013-01-01

Although much evidence supports the hypothesis that cognitive function and physical function are interrelated, it is unclear whether cognitive decline with mild cognitive impairment influences trainability of physical performance in exercise intervention. The purpose of this study was to examine the association between cognitive function at baseline and change in physical performance after exercise intervention in older adults with mild cognitive impairment. Forty-four older adults diagnosed with mild cognitive impairment based on the Peterson criteria (mean age 74.8 years) consented to and completed a 6-month twice weekly exercise intervention. The Timed Up and Go (TUG) test was used as a measure of physical performance. The Mini-Mental State Examination (MMSE), Trail Making Test Part B, Geriatric Depression Scale, baseline muscle strength of knee extension, and attendance rate of intervention, were measured as factors for predicting trainability. In the correlation analysis, the change in TUG showed modest correlations with attendance rate in the exercise program (r = -0.354, P = 0.027) and MMSE at baseline (r = -0.321, P = 0.034). A multiple regression analysis revealed that change in TUG was independently associated with attendance rate (β = -0.322, P = 0.026) and MMSE score (β = -0.295, P = 0.041), controlling for age and gender. General cognitive function was associated with improvements in physical performance after exercise intervention in subjects with mild cognitive impairment. Further research is needed to examine the effects of exercise programs designed to address cognitive obstacles in older adults with mild cognitive impairment.

The mathematics of the modernist villa architectural analysis using space syntax and isovists

CERN Document Server

Ostwald, Michael J

2018-01-01

This book presents the first detailed mathematical analysis of the social, cognitive and experiential properties of Modernist domestic architecture. The Modern Movement in architecture, which came to prominence during the first half of the twentieth century, may have been famous for its functional forms and machine-made aesthetic, but it also sought to challenge the way people inhabit, understand and experience space. Ludwig Mies van der Rohe’s buildings were not only minimalist and transparent, they were designed to subvert traditional social hierarchies. Frank Lloyd Wright’s organic Modernism not only attempted to negotiate a more responsive relationship between nature and architecture, but also shape the way people experience space. Richard Neutra’s Californian Modernism is traditionally celebrated for its sleek, geometric forms, but his intention was to use design to support a heightened understanding of context. Glenn Murcutt’s pristine pavilions, seemingly the epitome of regional Modernism, actu...

Local connectome phenotypes predict social, health, and cognitive factors

Directory of Open Access Journals (Sweden)

Michael A. Powell

2018-03-01

Full Text Available The unique architecture of the human connectome is defined initially by genetics and subsequently sculpted over time with experience. Thus, similarities in predisposition and experience that lead to similarities in social, biological, and cognitive attributes should also be reflected in the local architecture of white matter fascicles. Here we employ a method known as local connectome fingerprinting that uses diffusion MRI to measure the fiber-wise characteristics of macroscopic white matter pathways throughout the brain. This fingerprinting approach was applied to a large sample (N = 841 of subjects from the Human Connectome Project, revealing a reliable degree of between-subject correlation in the local connectome fingerprints, with a relatively complex, low-dimensional substructure. Using a cross-validated, high-dimensional regression analysis approach, we derived local connectome phenotype (LCP maps that could reliably predict a subset of subject attributes measured, including demographic, health, and cognitive measures. These LCP maps were highly specific to the attribute being predicted but also sensitive to correlations between attributes. Collectively, these results indicate that the local architecture of white matter fascicles reflects a meaningful portion of the variability shared between subjects along several dimensions. The local connectome is the pattern of fiber systems (i.e., number of fibers, orientation, and size within a voxel, and it reflects the proximal characteristics of white matter fascicles distributed throughout the brain. Here we show how variability in the local connectome is correlated in a principled way across individuals. This intersubject correlation is reliable enough that unique phenotype maps can be learned to predict between-subject variability in a range of social, health, and cognitive attributes. This work shows, for the first time, how the local connectome has both the sensitivity and the specificity to

Software architecture analysis tool : software architecture metrics collection

NARCIS (Netherlands)

Muskens, J.; Chaudron, M.R.V.; Westgeest, R.

2002-01-01

The Software Engineering discipline lacks the ability to evaluate software architectures. Here we describe a tool for software architecture analysis that is based on metrics. Metrics can be used to detect possible problems and bottlenecks in software architectures. Even though metrics do not give a

On the proposal of an intelligent support system with a cognitive architecture based on contextual modules for the operators of nuclear power plants

International Nuclear Information System (INIS)

Soares, Herculano Vieira; Alvarenga, Marco Antonio Bayout; Schirru, Roberto

2007-01-01

The operators' actions in a control room of a nuclear power plant are controlled by production rules in the emergency procedures of the operation manual. For each accident, there is a specific group of safety tasks composed of a set of specified actions. In this work we propose an intelligent support system based on a cognitive architecture composed of contextual modules, instead of functional modules. This approach consists on the determination of a task space, where we can define subspaces. In the subspaces where the set of values of the parameters is familiar, at least one of the rules in the procedural memory has its conditions completely satisfied. In this context, the proposed support system will be guided by an expert system, with a procedural memory composed of IF - THEN rules, that contains the input conditions with strict values of the parameters in the IF part, and a corresponding safety task in the THEN part. When the operator is in a situation in which the set of values of those variables falls in a non-familiar context, none of the rules in the procedural memory will have its conditions completely satisfied. In this context, it will be, then, utilized the connectionist part of the architecture, a fuzzy neural network (with radial activation functions), to classify the set of parameters and to choose a set of safety tasks applicable to the situation. The fuzzy logic provides an inference mechanism under uncertainty, while the neural network offers advantages of learning, adaptation, failure tolerance, parallelism and generalization. (author)

A surety engineering framework to reduce cognitive systems risks.

Energy Technology Data Exchange (ETDEWEB)

Caudell, Thomas P. (University of New Mexico, Albuquerque, NM); Peercy, David Eugene; Caldera, Eva O. (University of New Mexico, Albuquerque, NM); Shaneyfelt, Wendy L.

2008-12-01

Cognitive science research investigates the advancement of human cognition and neuroscience capabilities. Addressing risks associated with these advancements can counter potential program failures, legal and ethical issues, constraints to scientific research, and product vulnerabilities. Survey results, focus group discussions, cognitive science experts, and surety researchers concur technical risks exist that could impact cognitive science research in areas such as medicine, privacy, human enhancement, law and policy, military applications, and national security (SAND2006-6895). This SAND report documents a surety engineering framework and a process for identifying cognitive system technical, ethical, legal and societal risks and applying appropriate surety methods to reduce such risks. The framework consists of several models: Specification, Design, Evaluation, Risk, and Maturity. Two detailed case studies are included to illustrate the use of the process and framework. Several Appendices provide detailed information on existing cognitive system architectures; ethical, legal, and societal risk research; surety methods and technologies; and educing information research with a case study vignette. The process and framework provide a model for how cognitive systems research and full-scale product development can apply surety engineering to reduce perceived and actual risks.

Culture shapes the evolution of cognition

OpenAIRE

Thompson, Bill; Kirby, Simon; Smith, Kenny

2016-01-01

A central debate in cognitive science concerns the nativist hypothesis: the proposal that universal human behaviors are underpinned by strong, domain-specific, innate constraints on cognition. We use a general model of the processes that shape human behavior—learning, culture, and biological evolution—to test the evolutionary plausibility of this hypothesis. A series of analyses shows that culture radically alters the relationship between natural selection and cognition. Culture facilitates r...

Does the Cognitive Architecture of Simplex and Multiplex ASD Families Differ?

Science.gov (United States)

Oerlemans, Anoek M.; Hartman, Catharina A.; Franke, Barbara; Buitelaar, Jan K.; Rommelse, Nanda N. J.

2016-01-01

Children with an autism spectrum disorder (ASD) and their unaffected siblings from 54 simplex (SPX, one individual in the family affected) and 59 multiplex (MPX, two or more individuals affected) families, and 124 controls were assessed on intelligence, social cognition and executive functions. SPX and MPX ASD probands displayed similar cognitive…

Social Cognition in the Mirrors of «Cognitive Revolutions»

Directory of Open Access Journals (Sweden)

Khoroshilov D.A.

2017-12-01

Full Text Available The article discusses the problem of the social determination of cognition from the point of view of «cognitive revolutions» (R. Harré in dialogue between psychology, social theory and history, neurobiology and aesthetics. The research inquiry is the cultural-historical analysis of the social representations of the everyday life. The «aesthetic paradigm» (T.D. Martsinkovskaya uses the art-based methods to study the cultural forms of social cognition. Theoretical discussions are illustrated by the social psychological, clinical and contemporary art research of the mass consciousness of the Russian society at the beginning of the 21st century. The article presents the experience of the genre analysis of the tragedy of culture (G. Simmel, personal drama (L.S. Vygotsky and comedy of social life (A.P. Chekhov. The final result is a new aesthetic concept of social cognition.

Unibot, a Universal Agent Architecture for Robots

Directory of Open Access Journals (Sweden)

Saša Mladenović

2017-01-01

Full Text Available Today there are numerous robots in different applications domains despite the fact that they still have limitations in perception, actuation and decision process. Consequently, robots usually have limited autonomy, they are domain specific or have difficulty to adapt on new environments. Learning is the property that makes an agent intelligent and the crucial property that a robot should have to proliferate into the human society. Embedding the learning ability into the robot may simplify the development of the robot control mechanism. The motivation for this research is to develop the agent architecture of the universal robot – Unibot. In our approach the agent is the robot i.e. Unibot that acts in the physical world and is capable of learning. The Unibot conducts several simultaneous simulations of a problem of interest like path-finding. The novelty in our approach is the Multi-Agent Decision Support System which is developed and integrated into the Unibot agent architecture in order to execute simultaneous simulations. Furthermore, the Unibot calculates and evaluates between multiple solutions, decides which action should be performed and performs the action. The prototype of the Unibot agent architecture is described and evaluated in the experiment supported by the Lego Mindstorms robot and the NetLogo.