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Sample records for cluster pressure profile

  1. APPLICATION OF A SELF-SIMILAR PRESSURE PROFILE TO SUNYAEV-ZEL'DOVICH EFFECT DATA FROM GALAXY CLUSTERS

    International Nuclear Information System (INIS)

    Mroczkowski, Tony; Miller, Amber; Bonamente, Max; Carlstrom, John E.; Culverhouse, Thomas L.; Greer, Christopher; Hennessy, Ryan; Leitch, Erik M.; Loh, Michael; Marrone, Daniel P.; Pryke, Clem; Sharp, Matthew; Hawkins, David; Lamb, James W.; Woody, David; Joy, Marshall; Maughan, Ben; Muchovej, Stephen; Nagai, Daisuke

    2009-01-01

    We investigate the utility of a new, self-similar pressure profile for fitting Sunyaev-Zel'dovich (SZ) effect observations of galaxy clusters. Current SZ imaging instruments-such as the Sunyaev-Zel'dovich Array (SZA)-are capable of probing clusters over a large range in a physical scale. A model is therefore required that can accurately describe a cluster's pressure profile over a broad range of radii from the core of the cluster out to a significant fraction of the virial radius. In the analysis presented here, we fit a radial pressure profile derived from simulations and detailed X-ray analysis of relaxed clusters to SZA observations of three clusters with exceptionally high-quality X-ray data: A1835, A1914, and CL J1226.9+3332. From the joint analysis of the SZ and X-ray data, we derive physical properties such as gas mass, total mass, gas fraction and the intrinsic, integrated Compton y-parameter. We find that parameters derived from the joint fit to the SZ and X-ray data agree well with a detailed, independent X-ray-only analysis of the same clusters. In particular, we find that, when combined with X-ray imaging data, this new pressure profile yields an independent electron radial temperature profile that is in good agreement with spectroscopic X-ray measurements.

  2. Planck intermediate results: V. Pressure profiles of galaxy clusters from the Sunyaev-Zeldovich effect

    DEFF Research Database (Denmark)

    Bartlett, J.G.; Cardoso, J.-F.; Castex, G.

    2013-01-01

    that most clusters are individually detected at least out to R500. By stacking the radial profiles, we have statistically detected the radial SZ signal out to 3 × R500, i.e., at a density contrast of about 50-100, though the dispersion about the mean profile dominates the statistical errors across the whole......Taking advantage of the all-sky coverage and broadfrequency range of the Planck satellite, we study the Sunyaev-Zeldovich (SZ) and pressure profiles of 62 nearby massive clusters detected at high significance in the 14-month nominal survey. Careful reconstruction of the SZ signal indicates...... flatter than most predictions from numerical simulations. Combining the SZ and X-ray observed profiles into a joint fit to a generalised pressure profile gives best-fit parameters [P0,c500,γ, α,β] = [6.41,1.81,0.31,1.33,4.13]. Using a reasonable hypothesis for the gas temperature in the cluster outskirts...

  3. THE REDSHIFT EVOLUTION OF THE MEAN TEMPERATURE, PRESSURE, AND ENTROPY PROFILES IN 80 SPT-SELECTED GALAXY CLUSTERS

    Energy Technology Data Exchange (ETDEWEB)

    McDonald, M.; Benson, B. A.; Vikhlinin, A.; Aird, K. A.; Allen, S. W.; Bautz, M.; Bayliss, M.; Bleem, L. E.; Bocquet, S.; Brodwin, M.; Carlstrom, J. E.; Chang, C. L.; Cho, H. M.; Clocchiatti, A.; Crawford, T. M.; Crites, A. T.; de Haan, T.; Dobbs, M. A.; Foley, R. J.; Forman, W. R.; George, E. M.; Gladders, M. D.; Gonzalez, A. H.; Halverson, N. W.; Hlavacek-Larrondo, J.; Holder, G. P.; Holzapfel, W. L.; Hrubes, J. D.; Jones, C.; Keisler, R.; Knox, L.; Lee, A. T.; Leitch, E. M.; Liu, J.; Lueker, M.; Luong-Van, D.; Mantz, A.; Marrone, D. P.; McMahon, J. J.; Meyer, S. S.; Miller, E. D.; Mocanu, L.; Mohr, J. J.; Murray, S. S.; Padin, S.; Pryke, C.; Reichardt, C. L.; Rest, A.; Ruhl, J. E.; Saliwanchik, B. R.; Saro, A.; Sayre, J. T.; Schaffer, K. K.; Shirokoff, E.; Spieler, H. G.; Stalder, B.; Stanford, S. A.; Staniszewski, Z.; Stark, A. A.; Story, K. T.; Stubbs, C. W.; Vanderlinde, K.; Vieira, J. D.; Williamson, R.; Zahn, O.; Zenteno, A.

    2014-09-24

    We present the results of an X-ray analysis of 80 galaxy clusters selected in the 2500 deg(2) South Pole Telescope survey and observed with the Chandra X-ray Observatory. We divide the full sample into subsamples of ~20 clusters based on redshift and central density, performing a joint X-ray spectral fit to all clusters in a subsample simultaneously, assuming self-similarity of the temperature profile. This approach allows us to constrain the shape of the temperature profile over 0 < r < 1.5R (500), which would be impossible on a per-cluster basis, since the observations of individual clusters have, on average, 2000 X-ray counts. The results presented here represent the first constraints on the evolution of the average temperature profile from z = 0 to z = 1.2. We find that high-z (0.6 < z < 1.2) clusters are slightly (~30%) cooler both in the inner (r < 0.1R (500)) and outer (r > R (500)) regions than their low-z (0.3 < z < 0.6) counterparts. Combining the average temperature profile with measured gas density profiles from our earlier work, we infer the average pressure and entropy profiles for each subsample. Confirming earlier results from this data set, we find an absence of strong cool cores at high z, manifested in this analysis as a significantly lower observed pressure in the central 0.1R (500) of the high-z cool-core subset of clusters compared to the low-z cool-core subset. Overall, our observed pressure profiles agree well with earlier lower-redshift measurements, suggesting minimal redshift evolution in the pressure profile outside of the core. We find no measurable redshift evolution in the entropy profile at r lsim 0.7R (500)—this may reflect a long-standing balance between cooling and feedback over long timescales and large physical scales. We observe a slight flattening of the entropy profile at r gsim R (500) in our high-z subsample. This flattening is consistent with a temperature bias due to the enhanced (~3×) rate at which group-mass (~2

  4. Comparison of pressure profiles of massive relaxed galaxy clusters using the Sunyaev-Zel'dovich and x-ray data

    International Nuclear Information System (INIS)

    Bonamente, Massimiliano; Hasler, Nicole; Bulbul, Esra; Landry, David; Carlstrom, John E; Culverhouse, Thomas L; Gralla, Megan; Greer, Christopher; Hennessy, Ryan; Leitch, Erik M; Plagge, Thomas; Pryke, Clem; Hawkins, David; Lamb, James W; Muchovej, Stephen; Joy, Marshall; Kolodziejczak, Jeffery; Marrone, Daniel P; Miller, Amber; Mroczkowski, Tony

    2012-01-01

    We present the Sunyaev-Zel'dovich (SZ) effect observations of a sample of 25 massive relaxed galaxy clusters observed with the Sunyaev-Zel'dovich array (SZA), an eight-element interferometer that is part of the Combined Array for Research in Millimeter-wave Astronomy (CARMA). We performed an analysis of new SZA data and archival Chandra observations of this sample to investigate the integrated pressure—a proxy for cluster mass—determined from x-ray and SZ observations, two independent probes of the intra-cluster medium (ICM). This analysis makes use of a model for the ICM introduced by Bulbul (2010 Astrophys. J. 720 1038) which can be applied simultaneously to the SZ and x-ray data. With this model, we estimated the pressure profile for each cluster using a joint analysis of the SZ and x-ray data, and using the SZ data alone. We found that the integrated pressures measured from the x-ray and SZ data are consistent. This conclusion is in agreement with recent results obtained using WMAP and Planck data, confirming that SZ and x-ray observations of massive clusters detect the same amount of thermal pressure from the ICM. To test for possible biases introduced by our choice of model, we also fitted the SZ data using the universal pressure profile proposed by Arnaud (2010 Astron. Astrophys. 517 A92) and found consistency between the two models out to r 500 in the pressure profiles and integrated pressures. (paper)

  5. A multi-instrument non-parametric reconstruction of the electron pressure profile in the galaxy cluster CLJ1226.9+3332

    Science.gov (United States)

    Romero, C.; McWilliam, M.; Macías-Pérez, J.-F.; Adam, R.; Ade, P.; André, P.; Aussel, H.; Beelen, A.; Benoît, A.; Bideaud, A.; Billot, N.; Bourrion, O.; Calvo, M.; Catalano, A.; Coiffard, G.; Comis, B.; de Petris, M.; Désert, F.-X.; Doyle, S.; Goupy, J.; Kramer, C.; Lagache, G.; Leclercq, S.; Lestrade, J.-F.; Mauskopf, P.; Mayet, F.; Monfardini, A.; Pascale, E.; Perotto, L.; Pisano, G.; Ponthieu, N.; Revéret, V.; Ritacco, A.; Roussel, H.; Ruppin, F.; Schuster, K.; Sievers, A.; Triqueneaux, S.; Tucker, C.; Zylka, R.

    2018-04-01

    Context. In the past decade, sensitive, resolved Sunyaev-Zel'dovich (SZ) studies of galaxy clusters have become common. Whereas many previous SZ studies have parameterized the pressure profiles of galaxy clusters, non-parametric reconstructions will provide insights into the thermodynamic state of the intracluster medium. Aim. We seek to recover the non-parametric pressure profiles of the high redshift (z = 0.89) galaxy cluster CLJ 1226.9+3332 as inferred from SZ data from the MUSTANG, NIKA, Bolocam, and Planck instruments, which all probe different angular scales. Methods: Our non-parametric algorithm makes use of logarithmic interpolation, which under the assumption of ellipsoidal symmetry is analytically integrable. For MUSTANG, NIKA, and Bolocam we derive a non-parametric pressure profile independently and find good agreement among the instruments. In particular, we find that the non-parametric profiles are consistent with a fitted generalized Navaro-Frenk-White (gNFW) profile. Given the ability of Planck to constrain the total signal, we include a prior on the integrated Compton Y parameter as determined by Planck. Results: For a given instrument, constraints on the pressure profile diminish rapidly beyond the field of view. The overlap in spatial scales probed by these four datasets is therefore critical in checking for consistency between instruments. By using multiple instruments, our analysis of CLJ 1226.9+3332 covers a large radial range, from the central regions to the cluster outskirts: 0.05 R500 generation of SZ instruments such as NIKA2 and MUSTANG2.

  6. RESIDUAL GAS MOTIONS IN THE INTRACLUSTER MEDIUM AND BIAS IN HYDROSTATIC MEASUREMENTS OF MASS PROFILES OF CLUSTERS

    International Nuclear Information System (INIS)

    Lau, Erwin T.; Kravtsov, Andrey V.; Nagai, Daisuke

    2009-01-01

    We present analysis of bulk and random gas motions in the intracluster medium using high-resolution Eulerian cosmological simulations of 16 simulated clusters, including both very relaxed and unrelaxed systems and spanning a virial mass range of 5 x 10 13 - 2 x 10 15 h -1 M-odot. We investigate effects of the residual subsonic gas motions on the hydrostatic estimates of mass profiles and concentrations of galaxy clusters. In agreement with previous studies, we find that the gas motions contribute up to ∼5%-15% of the total pressure support in relaxed clusters with contribution increasing with the cluster-centric radius. The fractional pressure support is higher in unrelaxed systems. This contribution would not be accounted for in hydrostatic estimates of the total mass profile and would lead to systematic underestimate of mass. We demonstrate that total mass can be recovered accurately if pressure due to gas motions measured in simulations is explicitly taken into account in the equation of hydrostatic equilibrium. Given that the underestimate of mass is increasing at larger radii, where gas is less relaxed and contribution of gas motions to pressure is larger, the total density profile derived from hydrostatic analysis is more concentrated than the true profile. This may at least partially explain some high values of concentrations of clusters estimated from hydrostatic analysis of X-ray data.

  7. Velocity dispersion profiles of clusters of galaxies

    International Nuclear Information System (INIS)

    Struble, M.F.

    1979-01-01

    Velocity dispersion as a function of radius, called sigma/sub ls/ profiles, is presented for 13 clusters of galaxies having > or =30 radial velocities from both published and unpublished lists. A list of probable new members and possible outlying members for these clusters is also given. chi 2 and Kolmogoroff--Smirnoff one-sample tests for the goodness of fit of power laws to portions of the profiles indicate two significant structures in some profiles: (1) a local minimum corresponding to the local minimum noted in surface density or surface brightness profiles, and (2) a decrease in sigma/sub ls/ toward the cores. Both of these features are discussed in terms of a comparison with Wielen's N-body simulations. The sigma/sub ls/ profiles are placed in a new classification scheme which lends itself to interpreting clusters in a dynamical age sequence. The velocity field of galaxies at large distances from cluster centers is also discussed

  8. Modelling baryonic effects on galaxy cluster mass profiles

    Science.gov (United States)

    Shirasaki, Masato; Lau, Erwin T.; Nagai, Daisuke

    2018-06-01

    Gravitational lensing is a powerful probe of the mass distribution of galaxy clusters and cosmology. However, accurate measurements of the cluster mass profiles are limited by uncertainties in cluster astrophysics. In this work, we present a physically motivated model of baryonic effects on the cluster mass profiles, which self-consistently takes into account the impact of baryons on the concentration as well as mass accretion histories of galaxy clusters. We calibrate this model using the Omega500 hydrodynamical cosmological simulations of galaxy clusters with varying baryonic physics. Our model will enable us to simultaneously constrain cluster mass, concentration, and cosmological parameters using stacked weak lensing measurements from upcoming optical cluster surveys.

  9. Modelling Baryonic Effects on Galaxy Cluster Mass Profiles

    Science.gov (United States)

    Shirasaki, Masato; Lau, Erwin T.; Nagai, Daisuke

    2018-03-01

    Gravitational lensing is a powerful probe of the mass distribution of galaxy clusters and cosmology. However, accurate measurements of the cluster mass profiles are limited by uncertainties in cluster astrophysics. In this work, we present a physically motivated model of baryonic effects on the cluster mass profiles, which self-consistently takes into account the impact of baryons on the concentration as well as mass accretion histories of galaxy clusters. We calibrate this model using the Omega500 hydrodynamical cosmological simulations of galaxy clusters with varying baryonic physics. Our model will enable us to simultaneously constrain cluster mass, concentration, and cosmological parameters using stacked weak lensing measurements from upcoming optical cluster surveys.

  10. Study of pressure losses in the EL 4 cluster

    International Nuclear Information System (INIS)

    Berriaud, Ch.

    1964-01-01

    The evolution of research on the EL-4 cluster is examined here from the pressure losses point of view. These may be split up into separate pressure losses along the rode and in pressure losses corresponding to various particularities of the cluster. Tests have been carried out on series of three or four clusters placed in a channel. Water was first used, and then carbon dioxide at 60 bars. In all cases the following two parameters were varied: the Reynolds' number, and the rotation of a cluster around its axis with respect to the surrounding clusters. The influence of the gap between to successive clusters has also been studied. The first tests were carried out on clusters without jackets, the subsequent ones on clusters fitted with jackets. It was thus possible to study various types of element assemblies. The results are given in the form of curves representing: the evolution of the independent pressure loss coefficients as a function of the Reynolds number. (author) [fr

  11. Radiation pressure in super star cluster formation

    Science.gov (United States)

    Tsang, Benny T.-H.; Milosavljević, Miloš

    2018-05-01

    The physics of star formation at its extreme, in the nuclei of the densest and the most massive star clusters in the universe—potential massive black hole nurseries—has for decades eluded scrutiny. Spectroscopy of these systems has been scarce, whereas theoretical arguments suggest that radiation pressure on dust grains somehow inhibits star formation. Here, we harness an accelerated Monte Carlo radiation transport scheme to report a radiation hydrodynamical simulation of super star cluster formation in turbulent clouds. We find that radiation pressure reduces the global star formation efficiency by 30-35%, and the star formation rate by 15-50%, both relative to a radiation-free control run. Overall, radiation pressure does not terminate the gas supply for star formation and the final stellar mass of the most massive cluster is ˜1.3 × 106 M⊙. The limited impact as compared to in idealized theoretical models is attributed to a radiation-matter anti-correlation in the supersonically turbulent, gravitationally collapsing medium. In isolated regions outside massive clusters, where the gas distribution is less disturbed, radiation pressure is more effective in limiting star formation. The resulting stellar density at the cluster core is ≥108 M⊙ pc-3, with stellar velocity dispersion ≳ 70 km s-1. We conclude that the super star cluster nucleus is propitious to the formation of very massive stars via dynamical core collapse and stellar merging. We speculate that the very massive star may avoid the claimed catastrophic mass loss by continuing to accrete dense gas condensing from a gravitationally-confined ionized phase.

  12. THE LUMINOSITY PROFILES OF BRIGHTEST CLUSTER GALAXIES

    International Nuclear Information System (INIS)

    Donzelli, C. J.; Muriel, H.; Madrid, J. P.

    2011-01-01

    We have derived detailed R-band luminosity profiles and structural parameters for a total of 430 brightest cluster galaxies (BCGs), down to a limiting surface brightness of 24.5 mag arcsec -2 . Light profiles were initially fitted with a Sersic's R 1/n model, but we found that 205 (∼48%) BCGs require a double component model to accurately match their light profiles. The best fit for these 205 galaxies is an inner Sersic model, with indices n ∼ 1-7, plus an outer exponential component. Thus, we establish the existence of two categories of the BCG luminosity profiles: single and double component profiles. We found that double profile BCGs are brighter (∼0.2 mag) than single profile BCGs. In fact, the Kolmogorov-Smirnov test applied to these subsamples indicates that they have different total magnitude distributions, with mean values M R = -23.8 ± 0.6 mag for single profile BCGs and M R = -24.0 ± 0.5 mag for double profile BCGs. We find that partial luminosities for both subsamples are indistinguishable up to r = 15 kpc, while for r > 20 kpc the luminosities we obtain are on average 0.2 mag brighter for double profile BCGs. This result indicates that extra-light for double profile BCGs does not come from the inner region but from the outer regions of these galaxies. The best-fit slope of the Kormendy relation for the whole sample is a = 3.13 ± 0.04. However, when fitted separately, single and double profile BCGs show different slopes: a single = 3.29 ± 0.06 and a double = 2.79 ± 0.08. Also, the logarithmic slope of the metric luminosity α is higher in double profile BCGs (α double = 0.65 ± 0.12) than in single profile BCGs (α single = 0.59 ± 0.14). The mean isophote outer ellipticity (calculated at μ ∼ 24 mag arcsec -2 ) is higher in double profile BCGs (e double = 0.30 ± 0.10) than in single profile BCGs (e single = 0.26 ± 0.11). Similarly, the mean absolute value of inner minus outer ellipticity is also higher in double profile BCGs. From a

  13. MEASURING THE ULTIMATE HALO MASS OF GALAXY CLUSTERS: REDSHIFTS AND MASS PROFILES FROM THE HECTOSPEC CLUSTER SURVEY (HeCS)

    International Nuclear Information System (INIS)

    Rines, Kenneth; Geller, Margaret J.; Kurtz, Michael J.; Diaferio, Antonaldo

    2013-01-01

    The infall regions of galaxy clusters represent the largest gravitationally bound structures in a ΛCDM universe. Measuring cluster mass profiles into the infall regions provides an estimate of the ultimate mass of these halos. We use the caustic technique to measure cluster mass profiles from galaxy redshifts obtained with the Hectospec Cluster Survey (HeCS), an extensive spectroscopic survey of galaxy clusters with MMT/Hectospec. We survey 58 clusters selected by X-ray flux at 0.1 200 , a new observational cosmological test in essential agreement with simulations. Summed profiles binned in M 200 and in L X demonstrate that the predicted Navarro-Frenk-White form of the density profile is a remarkably good representation of the data in agreement with weak lensing results extending to large radius. The concentration of these summed profiles is also consistent with theoretical predictions.

  14. Reproducibility of Cognitive Profiles in Psychosis Using Cluster Analysis.

    Science.gov (United States)

    Lewandowski, Kathryn E; Baker, Justin T; McCarthy, Julie M; Norris, Lesley A; Öngür, Dost

    2018-04-01

    Cognitive dysfunction is a core symptom dimension that cuts across the psychoses. Recent findings support classification of patients along the cognitive dimension using cluster analysis; however, data-derived groupings may be highly determined by sampling characteristics and the measures used to derive the clusters, and so their interpretability must be established. We examined cognitive clusters in a cross-diagnostic sample of patients with psychosis and associations with clinical and functional outcomes. We then compared our findings to a previous report of cognitive clusters in a separate sample using a different cognitive battery. Participants with affective or non-affective psychosis (n=120) and healthy controls (n=31) were administered the MATRICS Consensus Cognitive Battery, and clinical and community functioning assessments. Cluster analyses were performed on cognitive variables, and clusters were compared on demographic, cognitive, and clinical measures. Results were compared to findings from our previous report. A four-cluster solution provided a good fit to the data; profiles included a neuropsychologically normal cluster, a globally impaired cluster, and two clusters of mixed profiles. Cognitive burden was associated with symptom severity and poorer community functioning. The patterns of cognitive performance by cluster were highly consistent with our previous findings. We found evidence of four cognitive subgroups of patients with psychosis, with cognitive profiles that map closely to those produced in our previous work. Clusters were associated with clinical and community variables and a measure of premorbid functioning, suggesting that they reflect meaningful groupings: replicable, and related to clinical presentation and functional outcomes. (JINS, 2018, 24, 382-390).

  15. CATCHprofiles: Clustering and Alignment Tool for ChIP Profiles

    DEFF Research Database (Denmark)

    G. G. Nielsen, Fiona; Galschiøt Markus, Kasper; Møllegaard Friborg, Rune

    2012-01-01

    IP-profiling data and detect potentially meaningful patterns, the areas of enrichment must be aligned and clustered, which is an algorithmically and computationally challenging task. We have developed CATCHprofiles, a novel tool for exhaustive pattern detection in ChIP profiling data. CATCHprofiles is built upon...... a computationally efficient implementation for the exhaustive alignment and hierarchical clustering of ChIP profiling data. The tool features a graphical interface for examination and browsing of the clustering results. CATCHprofiles requires no prior knowledge about functional sites, detects known binding patterns...... it an invaluable tool for explorative research based on ChIP profiling data. CATCHprofiles and the CATCH algorithm run on all platforms and is available for free through the CATCH website: http://catch.cmbi.ru.nl/. User support is available by subscribing to the mailing list catch-users@bioinformatics.org....

  16. Characterization of Omega-WINGS galaxy clusters. I. Stellar light and mass profiles

    Science.gov (United States)

    Cariddi, S.; D'Onofrio, M.; Fasano, G.; Poggianti, B. M.; Moretti, A.; Gullieuszik, M.; Bettoni, D.; Sciarratta, M.

    2018-02-01

    Context. Galaxy clusters are the largest virialized structures in the observable Universe. Knowledge of their properties provides many useful astrophysical and cosmological information. Aims: Our aim is to derive the luminosity and stellar mass profiles of the nearby galaxy clusters of the Omega-WINGS survey and to study the main scaling relations valid for such systems. Methods: We merged data from the WINGS and Omega-WINGS databases, sorted the sources according to the distance from the brightest cluster galaxy (BCG), and calculated the integrated luminosity profiles in the B and V bands, taking into account extinction, photometric and spatial completeness, K correction, and background contribution. Then, by exploiting the spectroscopic sample we derived the stellar mass profiles of the clusters. Results: We obtained the luminosity profiles of 46 galaxy clusters, reaching r200 in 30 cases, and the stellar mass profiles of 42 of our objects. We successfully fitted all the integrated luminosity growth profiles with one or two embedded Sérsic components, deriving the main clusters parameters. Finally, we checked the main scaling relation among the clusters parameters in comparison with those obtained for a selected sample of early-type galaxies (ETGs) of the same clusters. Conclusions: We found that the nearby galaxy clusters are non-homologous structures such as ETGs and exhibit a color-magnitude (CM) red-sequence relation very similar to that observed for galaxies in clusters. These properties are not expected in the current cluster formation scenarios. In particular the existence of a CM relation for clusters, shown here for the first time, suggests that the baryonic structures grow and evolve in a similar way at all scales.

  17. THE CONVERSION OF LATE-TYPE INTO EARLY-TYPE DWARF GALAXIES BY RAM-PRESSURE STRIPPING IN THE FORNAX CLUSTER

    International Nuclear Information System (INIS)

    De Rijcke, S.; Van Hese, E.; Buyle, P.

    2010-01-01

    We put to the test the hypothesis that the Fornax cluster dwarf galaxies are mostly a relatively recently acquired population, of which the star-forming, late-type members are converted into quiescent, early-type ones by ram-pressure stripping while being on orbits that plunge inside the inner few hundred kiloparsecs of the cluster. We construct dynamical models with different anisotropy profiles for the dwarf galaxy population and show that only extremely radially anisotropic orbital distributions are in agreement with the available morphological, positional, and kinematical data, especially with the radially increasing late-to-early-type ratio. This corroborates the idea that the Fornax cluster dwarfs are an infall population and that environmental factors, in this case ram-pressure stripping, play a prominent role in converting late-type dwarfs into early-type ones.

  18. PREDICTED SIZES OF PRESSURE-SUPPORTED HI CLOUDS IN THE OUTSKIRTS OF THE VIRGO CLUSTER

    Energy Technology Data Exchange (ETDEWEB)

    Burkhart, Blakesley; Loeb, Abraham [Harvard-Smithsonian Center for Astrophysics, 60 Garden St. Cambridge, MA (United States)

    2016-06-10

    Using data from the ALFALFA AGES Arecibo HI survey of galaxies and the Virgo cluster X-ray pressure profiles from XMM-Newton , we investigate the possibility that starless dark HI clumps, also known as “dark galaxies,” are supported by external pressure in the surrounding intercluster medium. We find that the starless HI clump masses, velocity dispersions, and positions allow these clumps to be in pressure equilibrium with the X-ray gas near the virial radius of the Virgo cluster. We predict the sizes of these clumps to range from 1 to 10 kpc, in agreement with the range of sizes found for spatially resolved HI starless clumps outside of Virgo. Based on the predicted HI surface density of the Virgo sources, as well as a sample of other similar resolved ALFALFA HI dark clumps with follow-up optical/radio observations, we predict that most of the HI dark clumps are on the cusp of forming stars. These HI sources therefore mark the transition between starless HI clouds and dwarf galaxies with stars.

  19. Genomic and Metabolomic Profile Associated to Clustering of Cardio-Metabolic Risk Factors.

    Science.gov (United States)

    Marrachelli, Vannina G; Rentero, Pilar; Mansego, María L; Morales, Jose Manuel; Galan, Inma; Pardo-Tendero, Mercedes; Martinez, Fernando; Martin-Escudero, Juan Carlos; Briongos, Laisa; Chaves, Felipe Javier; Redon, Josep; Monleon, Daniel

    2016-01-01

    To identify metabolomic and genomic markers associated with the presence of clustering of cardiometabolic risk factors (CMRFs) from a general population. One thousand five hundred and two subjects, Caucasian, > 18 years, representative of the general population, were included. Blood pressure measurement, anthropometric parameters and metabolic markers were measured. Subjects were grouped according the number of CMRFs (Group 1: profile was assessed by 1H NMR spectra using a Brucker Advance DRX 600 spectrometer. From the total population, 1217 (mean age 54±19, 50.6% men) with high genotyping call rate were analysed. A differential metabolomic profile, which included products from mitochondrial metabolism, extra mitochondrial metabolism, branched amino acids and fatty acid signals were observed among the three groups. The comparison of metabolomic patterns between subjects of Groups 1 to 3 for each of the genotypes associated to those subjects with three or more CMRFs revealed two SNPs, the rs174577_AA of FADS2 gene and the rs3803_TT of GATA2 transcription factor gene, with minimal or no statistically significant differences. Subjects with and without three or more CMRFs who shared the same genotype and metabolomic profile differed in the pattern of CMRFS cluster. Subjects of Group 3 and the AA genotype of the rs174577 had a lower prevalence of hypertension compared to the CC and CT genotype. In contrast, subjects of Group 3 and the TT genotype of the rs3803 polymorphism had a lower prevalence of T2DM, although they were predominantly males and had higher values of plasma creatinine. The results of the present study add information to the metabolomics profile and to the potential impact of genetic factors on the variants of clustering of cardiometabolic risk factors.

  20. Pressure pulsation measurements in pipe and cluster flows

    International Nuclear Information System (INIS)

    Benemann, A.; Voj, P.

    1976-01-01

    Measuring and evaluation techniques of pressure pulsations in pipe and cluster flows are described. The measurements were made on a 1 m long SNR rod-cluster and its feed and drain pipes. At Reynolds numbers in the cluster of 8.9 x 10 4 flow velocities of 14 m/sec were achieved. With the aid of a block diagram recording of the measured values by piezoelectric crystal and piezo-resistive strain gange as well as data processing are explained. For the analytical treatment of the pressure pulsation signals characterizing the turbulence field computer codes of a digital computer and a fast-fourier analyzer (Hewlett-Packard 5450 A) were used. The results show good agreement with theoretical curves on the behaviour of turbulent boundary layers of cluster and pipe flows at high Reynolds numbers. (TK) [de

  1. Comparison of Cluster Lensing Profiles with Lambda CDM Predictions

    Energy Technology Data Exchange (ETDEWEB)

    Broadhurst, Tom; /Tel Aviv U.; Umetsu, Keiichi; /Taipei, Inst. Astron. Astrophys.; Medezinski, Elinor; /Tel Aviv U.; Oguri, Masamune; /KIPAC, Menlo Park; Rephaeli, Yoel; /Tel Aviv U. /San Diego, CASS

    2008-05-21

    We derive lens distortion and magnification profiles of four well known clusters observed with Subaru. Each cluster is very well fitted by the general form predicted for Cold Dark Matter (CDM) dominated halos, with good consistency found between the independent distortion and magnification measurements. The inferred level of mass concentration is surprisingly high, 8 < c{sub vir} < 15 ( = 10.39 {+-} 0.91), compared to the relatively shallow profiles predicted by the {Lambda}CDM model, c{sub vir} = 5.06 {+-} 1.10 (for = 1.25 x 10{sup 15} M{sub {circle_dot}}/h). This represents a 4{sigma} discrepancy, and includes the relatively modest effects of projection bias and profile evolution derived from N-body simulations, which oppose each other with little residual effect. In the context of CDM based cosmologies, this discrepancy implies some modification of the widely assumed spectrum of initial density perturbations, so clusters collapse earlier (z {ge} 1) than predicted (z < 0.5) when the Universe was correspondingly denser.

  2. Clustering disaggregated load profiles using a Dirichlet process mixture model

    International Nuclear Information System (INIS)

    Granell, Ramon; Axon, Colin J.; Wallom, David C.H.

    2015-01-01

    Highlights: • We show that the Dirichlet process mixture model is scaleable. • Our model does not require the number of clusters as an input. • Our model creates clusters only by the features of the demand profiles. • We have used both residential and commercial data sets. - Abstract: The increasing availability of substantial quantities of power-use data in both the residential and commercial sectors raises the possibility of mining the data to the advantage of both consumers and network operations. We present a Bayesian non-parametric model to cluster load profiles from households and business premises. Evaluators show that our model performs as well as other popular clustering methods, but unlike most other methods it does not require the number of clusters to be predetermined by the user. We used the so-called ‘Chinese restaurant process’ method to solve the model, making use of the Dirichlet-multinomial distribution. The number of clusters grew logarithmically with the quantity of data, making the technique suitable for scaling to large data sets. We were able to show that the model could distinguish features such as the nationality, household size, and type of dwelling between the cluster memberships

  3. Modeling and clustering users with evolving profiles in usage streams

    KAUST Repository

    Zhang, Chongsheng; Masseglia, Florent; Zhang, Xiangliang

    2012-01-01

    Today, there is an increasing need of data stream mining technology to discover important patterns on the fly. Existing data stream models and algorithms commonly assume that users' records or profiles in data streams will not be updated or revised once they arrive. Nevertheless, in various applications such asWeb usage, the records/profiles of the users can evolve along time. This kind of streaming data evolves in two forms, the streaming of tuples or transactions as in the case of traditional data streams, and more importantly, the evolving of user records/profiles inside the streams. Such data streams bring difficulties on modeling and clustering for exploring users' behaviors. In this paper, we propose three models to summarize this kind of data streams, which are the batch model, the Evolving Objects (EO) model and the Dynamic Data Stream (DDS) model. Through creating, updating and deleting user profiles, these models summarize the behaviors of each user as a profile object. Based upon these models, clustering algorithms are employed to discover interesting user groups from the profile objects. We have evaluated all the proposed models on a large real-world data set, showing that the DDS model summarizes the data streams with evolving tuples more efficiently and effectively, and provides better basis for clustering users than the other two models. © 2012 IEEE.

  4. Modeling and clustering users with evolving profiles in usage streams

    KAUST Repository

    Zhang, Chongsheng

    2012-09-01

    Today, there is an increasing need of data stream mining technology to discover important patterns on the fly. Existing data stream models and algorithms commonly assume that users\\' records or profiles in data streams will not be updated or revised once they arrive. Nevertheless, in various applications such asWeb usage, the records/profiles of the users can evolve along time. This kind of streaming data evolves in two forms, the streaming of tuples or transactions as in the case of traditional data streams, and more importantly, the evolving of user records/profiles inside the streams. Such data streams bring difficulties on modeling and clustering for exploring users\\' behaviors. In this paper, we propose three models to summarize this kind of data streams, which are the batch model, the Evolving Objects (EO) model and the Dynamic Data Stream (DDS) model. Through creating, updating and deleting user profiles, these models summarize the behaviors of each user as a profile object. Based upon these models, clustering algorithms are employed to discover interesting user groups from the profile objects. We have evaluated all the proposed models on a large real-world data set, showing that the DDS model summarizes the data streams with evolving tuples more efficiently and effectively, and provides better basis for clustering users than the other two models. © 2012 IEEE.

  5. Cluster formation in in-service thermally aged pressurizer welds

    Science.gov (United States)

    Lindgren, Kristina; Boåsen, Magnus; Stiller, Krystyna; Efsing, Pål; Thuvander, Mattias

    2018-06-01

    Thermal aging of reactor pressure vessel steel welds at elevated temperatures may affect the ductile-to-brittle transition temperature. In this study, unique weld material from a pressurizer, with a composition similar to that of the reactor pressure vessel, that has been in operation for 28 years at 345 °C is examined. Despite the relatively low temperature, the weld becomes hardened during operation. This is attributed to nanometre sized Cu-rich clusters, mainly located at Mo- and C-enriched dislocation lines and on boundaries. The welds have been characterized using atom probe tomography, and the characteristics of the precipitates/clusters is related to the hardness increase, giving the best agreement for the Russell-Brown model.

  6. Self-similarity of temperature profiles in distant galaxy clusters: the quest for a universal law

    Science.gov (United States)

    Baldi, A.; Ettori, S.; Molendi, S.; Gastaldello, F.

    2012-09-01

    Context. We present the XMM-Newton temperature profiles of 12 bright (LX > 4 × 1044 erg s-1) clusters of galaxies at 0.4 high-redshift clusters, to investigate their properties, and to define a universal law to describe the temperature radial profiles in galaxy clusters as a function of both cosmic time and their state of relaxation. Methods: We performed a spatially resolved spectral analysis, using Cash statistics, to measure the temperature in the intracluster medium at different radii. Results: We extracted temperature profiles for the clusters in our sample, finding that all profiles are declining toward larger radii. The normalized temperature profiles (normalized by the mean temperature T500) are found to be generally self-similar. The sample was subdivided into five cool-core (CC) and seven non cool-core (NCC) clusters by introducing a pseudo-entropy ratio σ = (TIN/TOUT) × (EMIN/EMOUT)-1/3 and defining the objects with σ ratio σ is detected by fitting a function of r and σ, showing an indication that the outer part of the profiles becomes steeper for higher values of σ (i.e. transitioning toward the NCC clusters). No significant evidence of redshift evolution could be found within the redshift range sampled by our clusters (0.4 high-z sample with intermediate clusters at 0.1 0.4 has been attempted. We were able to define the closest possible relation to a universal law for the temperature profiles of galaxy clusters at 0.1 < z < 0.9, showing a dependence on both the relaxation state of the clusters and the redshift. Appendix A is only available in electronic form at http://www.aanda.org

  7. Coping profiles, perceived stress and health-related behaviors: a cluster analysis approach.

    Science.gov (United States)

    Doron, Julie; Trouillet, Raphael; Maneveau, Anaïs; Ninot, Grégory; Neveu, Dorine

    2015-03-01

    Using cluster analytical procedure, this study aimed (i) to determine whether people could be differentiated on the basis of coping profiles (or unique combinations of coping strategies); and (ii) to examine the relationships between these profiles and perceived stress and health-related behaviors. A sample of 578 French students (345 females, 233 males; M(age)= 21.78, SD(age)= 2.21) completed the Perceived Stress Scale-14 ( Bruchon-Schweitzer, 2002), the Brief COPE ( Muller and Spitz, 2003) and a series of items measuring health-related behaviors. A two-phased cluster analytic procedure (i.e. hierarchical and non-hierarchical-k-means) was employed to derive clusters of coping strategy profiles. The results yielded four distinctive coping profiles: High Copers, Adaptive Copers, Avoidant Copers and Low Copers. The results showed that clusters differed significantly in perceived stress and health-related behaviors. High Copers and Avoidant Copers displayed higher levels of perceived stress and engaged more in unhealthy behavior, compared with Adaptive Copers and Low Copers who reported lower levels of stress and engaged more in healthy behaviors. These findings suggested that individuals' relative reliance on some strategies and de-emphasis on others may be a more advantageous way of understanding the manner in which individuals cope with stress. Therefore, cluster analysis approach may provide an advantage over more traditional statistical techniques by identifying distinct coping profiles that might best benefit from interventions. Future research should consider coping profiles to provide a deeper understanding of the relationships between coping strategies and health outcomes and to identify risk groups. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  8. Planck intermediate results. X. Physics of the hot gas in the Coma cluster

    DEFF Research Database (Denmark)

    Planck Collaboration,; Ade, P. A. R.; Aghanim, N.

    2013-01-01

    We present an analysis of Planck satellite data on the Coma Cluster observed via the Sunyaev-Zeldovich effect. Planck is able, for the first time, to detect SZ emission up to r ~ 3 X R_500. We test previously proposed models for the pressure distribution in clusters against the azimuthally averaged...... data. We find that the Arnaud et al. universal pressure profile does not fit Coma, and that their pressure profile for merging systems provides a good fit of the data only at rR_500 than the mean pressure profile predicted by the simulations. The Planck image shows significant local steepening of the y...

  9. Observed damage during Argon gas cluster depth profiles of compound semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Barlow, Anders J., E-mail: anders.barlow@ncl.ac.uk; Portoles, Jose F.; Cumpson, Peter J. [National EPSRC XPS Users' Service (NEXUS), School of Mechanical and Systems Engineering, Newcastle University, Newcastle upon Tyne NE1 7RU (United Kingdom)

    2014-08-07

    Argon Gas Cluster Ion Beam (GCIB) sources have become very popular in XPS and SIMS in recent years, due to the minimal chemical damage they introduce in the depth-profiling of polymer and other organic materials. These GCIB sources are therefore particularly useful for depth-profiling polymer and organic materials, but also (though more slowly) the surfaces of inorganic materials such as semiconductors, due to the lower roughness expected in cluster ion sputtering compared to that introduced by monatomic ions. We have examined experimentally a set of five compound semiconductors, cadmium telluride (CdTe), gallium arsenide (GaAs), gallium phosphide (GaP), indium arsenide (InAs), and zinc selenide (ZnSe) and a high-κ dielectric material, hafnium oxide (HfO), in their response to argon cluster profiling. An experimentally determined HfO etch rate of 0.025 nm/min (3.95 × 10{sup −2} amu/atom in ion) for 6 keV Ar gas clusters is used in the depth scale conversion for the profiles of the semiconductor materials. The assumption has been that, since the damage introduced into polymer materials is low, even though sputter yields are high, then there is little likelihood of damaging inorganic materials at all with cluster ions. This seems true in most cases; however, in this work, we report for the first time that this damage can in fact be very significant in the case of InAs, causing the formation of metallic indium that is readily visible even to the naked eye.

  10. Profiling physical activity motivation based on self-determination theory: a cluster analysis approach.

    Science.gov (United States)

    Friederichs, Stijn Ah; Bolman, Catherine; Oenema, Anke; Lechner, Lilian

    2015-01-01

    In order to promote physical activity uptake and maintenance in individuals who do not comply with physical activity guidelines, it is important to increase our understanding of physical activity motivation among this group. The present study aimed to examine motivational profiles in a large sample of adults who do not comply with physical activity guidelines. The sample for this study consisted of 2473 individuals (31.4% male; age 44.6 ± 12.9). In order to generate motivational profiles based on motivational regulation, a cluster analysis was conducted. One-way analyses of variance were then used to compare the clusters in terms of demographics, physical activity level, motivation to be active and subjective experience while being active. Three motivational clusters were derived based on motivational regulation scores: a low motivation cluster, a controlled motivation cluster and an autonomous motivation cluster. These clusters differed significantly from each other with respect to physical activity behavior, motivation to be active and subjective experience while being active. Overall, the autonomous motivation cluster displayed more favorable characteristics compared to the other two clusters. The results of this study provide additional support for the importance of autonomous motivation in the context of physical activity behavior. The three derived clusters may be relevant in the context of physical activity interventions as individuals within the different clusters might benefit most from different intervention approaches. In addition, this study shows that cluster analysis is a useful method for differentiating between motivational profiles in large groups of individuals who do not comply with physical activity guidelines.

  11. Mass profile and dynamical status of the z ~ 0.8 galaxy cluster LCDCS 0504

    Science.gov (United States)

    Guennou, L.; Biviano, A.; Adami, C.; Limousin, M.; Lima Neto, G. B.; Mamon, G. A.; Ulmer, M. P.; Gavazzi, R.; Cypriano, E. S.; Durret, F.; Clowe, D.; LeBrun, V.; Allam, S.; Basa, S.; Benoist, C.; Cappi, A.; Halliday, C.; Ilbert, O.; Johnston, D.; Jullo, E.; Just, D.; Kubo, J. M.; Márquez, I.; Marshall, P.; Martinet, N.; Maurogordato, S.; Mazure, A.; Murphy, K. J.; Plana, H.; Rostagni, F.; Russeil, D.; Schirmer, M.; Schrabback, T.; Slezak, E.; Tucker, D.; Zaritsky, D.; Ziegler, B.

    2014-06-01

    Context. Constraints on the mass distribution in high-redshift clusters of galaxies are currently not very strong. Aims: We aim to constrain the mass profile, M(r), and dynamical status of the z ~ 0.8 LCDCS 0504 cluster of galaxies that is characterized by prominent giant gravitational arcs near its center. Methods: Our analysis is based on deep X-ray, optical, and infrared imaging as well as optical spectroscopy, collected with various instruments, which we complemented with archival data. We modeled the mass distribution of the cluster with three different mass density profiles, whose parameters were constrained by the strong lensing features of the inner cluster region, by the X-ray emission from the intracluster medium, and by the kinematics of 71 cluster members. Results: We obtain consistent M(r) determinations from three methods based on kinematics (dispersion-kurtosis, caustics, and MAMPOSSt), out to the cluster virial radius, ≃1.3 Mpc and beyond. The mass profile inferred by the strong lensing analysis in the central cluster region is slightly higher than, but still consistent with, the kinematics estimate. On the other hand, the X-ray based M(r) is significantly lower than the kinematics and strong lensing estimates. Theoretical predictions from ΛCDM cosmology for the concentration-mass relation agree with our observational results, when taking into account the uncertainties in the observational and theoretical estimates. There appears to be a central deficit in the intracluster gas mass fraction compared with nearby clusters. Conclusions: Despite the relaxed appearance of this cluster, the determinations of its mass profile by different probes show substantial discrepancies, the origin of which remains to be determined. The extension of a dynamical analysis similar to that of other clusters of the DAFT/FADA survey with multiwavelength data of sufficient quality will allow shedding light on the possible systematics that affect the determination of mass

  12. Lensing Constraints on the Mass Profile Shape and the Splashback Radius of Galaxy Clusters

    Science.gov (United States)

    Umetsu, Keiichi; Diemer, Benedikt

    2017-02-01

    The lensing signal around galaxy clusters can, in principle, be used to test detailed predictions for their average mass profile from numerical simulations. However, the intrinsic shape of the profiles can be smeared out when a sample that spans a wide range of cluster masses is averaged in physical length units. This effect especially conceals rapid changes in gradient such as the steep drop associated with the splashback radius, a sharp edge corresponding to the outermost caustic in accreting halos. We optimize the extraction of such local features by scaling individual halo profiles to a number of spherical overdensity radii, and apply this method to 16 X-ray-selected, high-mass clusters targeted in the Cluster Lensing And Supernova survey with Hubble. By forward-modeling the weak- and strong-lensing data presented by Umetsu et al., we show that, regardless of the scaling overdensity, the projected ensemble density profile is remarkably well described by a Navarro-Frenk-White (NFW) or Einasto profile out to R˜ 2.5 {h}-1 {Mpc}, beyond which the profiles flatten. We constrain the NFW concentration to {c}200{{c}}=3.66+/- 0.11 at {M}200{{c}}≃ 1.0× {10}15 {h}-1 {M}⊙ , consistent with and improved from previous work that used conventionally stacked lensing profiles, and in excellent agreement with theoretical expectations. Assuming the profile form of Diemer & Kravtsov and generic priors calibrated from numerical simulations, we place a lower limit on the splashback radius of the cluster halos, if it exists, of {R}{sp}3{{D}}/{r}200{{m}}> 0.89 ({R}{sp}3{{D}}> 1.83 {h}-1 {Mpc}) at 68% confidence. The corresponding density feature is most pronounced when the cluster profiles are scaled by {r}200{{m}}, and smeared out when scaled to higher overdensities. Based in part on data collected at the Subaru Telescope, which is operated by the National Astronomical Society of Japan.

  13. MOTIVATIONAL CLUSTER PROFILES OF ADOLESCENT ATHLETES: AN EXAMINATION OF DIFFERENCES IN PHYSICAL-SELF PERCEPTION

    Directory of Open Access Journals (Sweden)

    Emine Çağlar

    2010-06-01

    Full Text Available The primary purpose of the present study was to identify motivational profiles of adolescent athletes using cluster analysis in non-Western culture. A second purpose was to examine relationships between physical self-perception differences of adolescent athletes and motivational profiles. One hundred and thirty six male (Mage = 17.46, SD = 1.25 years and 80 female adolescent athletes (Mage = 17.61, SD = 1.19 years from a variety of team sports including basketball, soccer, volleyball, and handball volunteered to participate in this study. The Sport Motivation Scale (SMS and Physical Self-Perception Profile (PSPP were administered to all participants. Hierarchical cluster analysis revealed a four-cluster solution for this sample: amotivated, low motivated, moderate motivated, and highly motivated. A 4 x 5 (Cluster x PSPP Subscales MANOVA revealed no significant main effect of motivational clusters on physical self-perception levels (p > 0.05. As a result, findings of the present study showed that motivational types of the adolescent athletes constituted four different motivational clusters. Highly and moderate motivated athletes consistently scored higher than amotivated athletes on the perceived sport competence, physical condition, and physical self-worth subscales of PSPP. This study identified motivational profiles of competitive youth-sport participants

  14. The Splashback Feature around DES Galaxy Clusters: Galaxy Density and Weak Lensing Profiles

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Chihway; et al.

    2017-10-18

    Splashback refers to the process of matter that is accreting onto a dark matter halo reaching its first orbital apocenter and turning around in its orbit. The cluster-centric radius at which this process occurs, r_sp, defines a halo boundary that is connected to the dynamics of the cluster, in contrast with other common halo boundary definitions such as R_200. A rapid decline in the matter density profile of the halo is expected near r_sp. We measure the galaxy number density and weak lensing mass profiles around RedMapper galaxy clusters in the first year Dark Energy Survey (DES) data. For a cluster sample with mean mass ~2.5 x 10^14 solar masses, we find strong evidence of a splashback-like steepening of the galaxy density profile and measure r_sp=1.16 +/- 0.08 Mpc/h, consistent with earlier SDSS measurements of More et al. (2016) and Baxter et al. (2017). Moreover, our weak lensing measurement demonstrates for the first time the existence of a splashback-like steepening of the matter profile of galaxy clusters. We measure r_sp=1.28 +/- 0.18 Mpc/h from the weak lensing data, in good agreement with our galaxy density measurements. Applying our analysis to different cluster and galaxy samples, we find that consistent with LambdaCDM simulations, r_sp scales with R_200m and does not evolve with redshift over the redshift range of 0.3--0.6. We also find that potential systematic effects associated with the RedMapper algorithm may impact the location of r_sp, in particular the choice of scale used to estimate cluster richness. We discuss progress needed to understand the systematic uncertainties and fully exploit forthcoming data from DES and future surveys, emphasizing the importance of more realistic mock catalogs and independent cluster samples.

  15. ENTROPY AT THE OUTSKIRTS OF GALAXY CLUSTERS AS IMPLICATIONS FOR COSMOLOGICAL COSMIC-RAY ACCELERATION

    International Nuclear Information System (INIS)

    Fujita, Yutaka; Ohira, Yutaka; Yamazaki, Ryo

    2013-01-01

    Recently, gas entropy at the outskirts of galaxy clusters has attracted much attention. We propose that the entropy profiles could be used to study cosmic-ray (CR) acceleration around the clusters. If the CRs are effectively accelerated at the formation of clusters, the kinetic energy of infalling gas is consumed by the acceleration and the gas entropy should decrease. As a result, the entropy profiles become flat at the outskirts. If the acceleration is not efficient, the entropy should continue to increase outward. By comparing model predictions with X-ray observations with Suzaku, which show flat entropy profiles, we find that the CRs have carried ∼< 7% of the kinetic energy of the gas away from the clusters. Moreover, the CR pressure at the outskirts can be ∼< 40% of the total pressure. On the other hand, if the entropy profiles are not flat at the outskirts, as indicated by combined Plank and ROSAT observations, the carried energy and the CR pressure should be much smaller than the above estimations.

  16. Theory and discretization of ideal magnetohydrodynamic equilibria with fractal pressure profiles

    Science.gov (United States)

    Kraus, B. F.; Hudson, S. R.

    2017-09-01

    In three-dimensional ideal magnetohydrodynamics, closed flux surfaces cannot maintain both rational rotational-transform and pressure gradients, as these features together produce unphysical, infinite currents. A proposed set of equilibria nullifies these currents by flattening the pressure on sufficiently wide intervals around each rational surface. Such rational surfaces exist at every scale, which characterizes the pressure profile as self-similar and thus fractal. The pressure profile is approximated numerically by considering a finite number of rational regions and analyzed mathematically by classifying the irrational numbers that support gradients into subsets. Applying these results to a given rotational-transform profile in cylindrical geometry, we find magnetic field and current density profiles compatible with the fractal pressure.

  17. ADPROCLUS: a graphical user interface for fitting additive profile clustering models to object by variable data matrices.

    Science.gov (United States)

    Wilderjans, Tom F; Ceulemans, Eva; Van Mechelen, Iven; Depril, Dirk

    2011-03-01

    In many areas of psychology, one is interested in disclosing the underlying structural mechanisms that generated an object by variable data set. Often, based on theoretical or empirical arguments, it may be expected that these underlying mechanisms imply that the objects are grouped into clusters that are allowed to overlap (i.e., an object may belong to more than one cluster). In such cases, analyzing the data with Mirkin's additive profile clustering model may be appropriate. In this model: (1) each object may belong to no, one or several clusters, (2) there is a specific variable profile associated with each cluster, and (3) the scores of the objects on the variables can be reconstructed by adding the cluster-specific variable profiles of the clusters the object in question belongs to. Until now, however, no software program has been publicly available to perform an additive profile clustering analysis. For this purpose, in this article, the ADPROCLUS program, steered by a graphical user interface, is presented. We further illustrate its use by means of the analysis of a patient by symptom data matrix.

  18. Accurate confidence aware clustering of array CGH tumor profiles.

    NARCIS (Netherlands)

    van Houte, B.P.P.; Heringa, J.

    2010-01-01

    Motivation: Chromosomal aberrations tend to be characteristic for given (sub)types of cancer. Such aberrations can be detected with array comparative genomic hybridization (aCGH). Clustering aCGH tumor profiles aids in identifying chromosomal regions of interest and provides useful diagnostic

  19. Neuro- and social-cognitive clustering highlights distinct profiles in adults with anorexia nervosa.

    Science.gov (United States)

    Renwick, Beth; Musiat, Peter; Lose, Anna; DeJong, Hannah; Broadbent, Hannah; Kenyon, Martha; Loomes, Rachel; Watson, Charlotte; Ghelani, Shreena; Serpell, Lucy; Richards, Lorna; Johnson-Sabine, Eric; Boughton, Nicky; Treasure, Janet; Schmidt, Ulrike

    2015-01-01

    This study aimed to explore the neuro- and social-cognitive profile of a consecutive series of adult outpatients with anorexia nervosa (AN) when compared with widely available age and gender matched historical control data. The relationship between performance profiles, clinical characteristics, service utilization, and treatment adherence was also investigated. Consecutively recruited outpatients with a broad diagnosis of AN (restricting subtype AN-R: n = 44, binge-purge subtype AN-BP: n = 33 or Eating Disorder Not Otherwise Specified-AN subtype EDNOS-AN: n = 23) completed a comprehensive set of neurocognitive (set-shifting, central coherence) and social-cognitive measures (Emotional Theory of Mind). Data were subjected to hierarchical cluster analysis and a discriminant function analysis. Three separate, meaningful clusters emerged. Cluster 1 (n = 45) showed overall average to high average neuro- and social- cognitive performance, Cluster 2 (n = 38) showed mixed performance characterized by distinct strengths and weaknesses, and Cluster 3 (n = 17) showed poor overall performance (Autism Spectrum disorder (ASD) like cluster). The three clusters did not differ in terms of eating disorder symptoms, comorbid features or service utilization and treatment adherence. A discriminant function analysis confirmed that the clusters were best characterized by performance in perseveration and set-shifting measures. The findings suggest that considerable neuro- and social-cognitive heterogeneity exists in patients with AN, with a subset showing ASD-like features. The value of this method of profiling in predicting longer term patient outcomes and in guiding development of etiologically targeted treatments remains to be seen. © 2014 Wiley Periodicals, Inc.

  20. Effect of radiation pressure in the cores of globular clusters

    Energy Technology Data Exchange (ETDEWEB)

    Angeletti, L; Capuzzo-Dolcetta, R; Giannone

    1981-10-01

    The possible effects of a presence of a dust cloud in the cores of globular clusters was investigated. Two cluster models were considered together with various models of clouds. The problem of radiation transfer was solved under some simplifying assumptions. Owing to a differential absorption of the star light in the cloud, radiation pressure turned out be inward-directed in some cloud models. This fact may lead to a confinement of some dust in the central regions of globular clusters.

  1. Ambulatory blood pressure profiles in familial dysautonomia.

    Science.gov (United States)

    Goldberg, Lior; Bar-Aluma, Bat-El; Krauthammer, Alex; Efrati, Ori; Sharabi, Yehonatan

    2018-02-12

    Familial dysautonomia (FD) is a rare genetic disease that involves extreme blood pressure fluctuations secondary to afferent baroreflex failure. The diurnal blood pressure profile, including the average, variability, and day-night difference, may have implications for long-term end organ damage. The purpose of this study was to describe the circadian pattern of blood pressure in the FD population and relationships with renal and pulmonary function, use of medications, and overall disability. We analyzed 24-h ambulatory blood pressure monitoring recordings in 22 patients with FD. Information about medications, disease severity, renal function (estimated glomerular filtration, eGFR), pulmonary function (forced expiratory volume in 1 s, FEV1) and an index of blood pressure variability (standard deviation of systolic pressure) were analyzed. The mean (± SEM) 24-h blood pressure was 115 ± 5.6/72 ± 2.0 mmHg. The diurnal blood pressure variability was high (daytime systolic pressure standard deviation 22.4 ± 1.5 mmHg, nighttime 17.2 ± 1.6), with a high frequency of a non-dipping pattern (16 patients, 73%). eGFR, use of medications, FEV1, and disability scores were unrelated to the degree of blood pressure variability or to dipping status. This FD cohort had normal average 24-h blood pressure, fluctuating blood pressure, and a high frequency of non-dippers. Although there was evidence of renal dysfunction based on eGFR and proteinuria, the ABPM profile was unrelated to the measures of end organ dysfunction or to reported disability.

  2. MMPI-2: Cluster Analysis of Personality Profiles in Perinatal Depression—Preliminary Evidence

    Directory of Open Access Journals (Sweden)

    Valentina Meuti

    2014-01-01

    Full Text Available Background. To assess personality characteristics of women who develop perinatal depression. Methods. The study started with a screening of a sample of 453 women in their third trimester of pregnancy, to which was administered a survey data form, the Edinburgh Postnatal Depression Scale (EPDS and the Minnesota Multiphasic Personality Inventory 2 (MMPI-2. A clinical group of subjects with perinatal depression (PND, 55 subjects was selected; clinical and validity scales of MMPI-2 were used as predictors in hierarchical cluster analysis carried out. Results. The analysis identified three clusters of personality profile: two “clinical” clusters (1 and 3 and an “apparently common” one (cluster 2. The first cluster (39.5% collects structures of personality with prevalent obsessive or dependent functioning tending to develop a “psychasthenic” depression; the third cluster (13.95% includes women with prevalent borderline functioning tending to develop “dysphoric” depression; the second cluster (46.5% shows a normal profile with a “defensive” attitude, probably due to the presence of defense mechanisms or to the fear of stigma. Conclusion. Characteristics of personality have a key role in clinical manifestations of perinatal depression; it is important to detect them to identify mothers at risk and to plan targeted therapeutic interventions.

  3. MMPI-2: Cluster Analysis of Personality Profiles in Perinatal Depression—Preliminary Evidence

    Science.gov (United States)

    Grillo, Alessandra; Lauriola, Marco; Giacchetti, Nicoletta

    2014-01-01

    Background. To assess personality characteristics of women who develop perinatal depression. Methods. The study started with a screening of a sample of 453 women in their third trimester of pregnancy, to which was administered a survey data form, the Edinburgh Postnatal Depression Scale (EPDS) and the Minnesota Multiphasic Personality Inventory 2 (MMPI-2). A clinical group of subjects with perinatal depression (PND, 55 subjects) was selected; clinical and validity scales of MMPI-2 were used as predictors in hierarchical cluster analysis carried out. Results. The analysis identified three clusters of personality profile: two “clinical” clusters (1 and 3) and an “apparently common” one (cluster 2). The first cluster (39.5%) collects structures of personality with prevalent obsessive or dependent functioning tending to develop a “psychasthenic” depression; the third cluster (13.95%) includes women with prevalent borderline functioning tending to develop “dysphoric” depression; the second cluster (46.5%) shows a normal profile with a “defensive” attitude, probably due to the presence of defense mechanisms or to the fear of stigma. Conclusion. Characteristics of personality have a key role in clinical manifestations of perinatal depression; it is important to detect them to identify mothers at risk and to plan targeted therapeutic interventions. PMID:25574499

  4. THERMODYNAMICS OF THE COMA CLUSTER OUTSKIRTS

    International Nuclear Information System (INIS)

    Simionescu, A.; Werner, N.; Urban, O.; Allen, S. W.; Fabian, A. C.; Sanders, J. S.; Walker, S. A.; Mantz, A.; Matsushita, K.; Sasaki, T.; Sato, T.; Nulsen, P. E. J.; Takei, Y.

    2013-01-01

    We present results from a large mosaic of Suzaku observations of the Coma Cluster, the nearest and X-ray brightest hot (∼8 keV), dynamically active, non-cool core system, focusing on the thermodynamic properties of the intracluster medium on large scales. For azimuths not aligned with an infalling subcluster toward the southwest, our measured temperature and X-ray brightness profiles exhibit broadly consistent radial trends, with the temperature decreasing from about 8.5 keV at the cluster center to about 2 keV at a radius of 2 Mpc, which is the edge of our detection limit. The southwest merger significantly boosts the surface brightness, allowing us to detect X-ray emission out to ∼2.2 Mpc along this direction. Apart from the southwestern infalling subcluster, the surface brightness profiles show multiple edges around radii of 30-40 arcmin. The azimuthally averaged temperature profile, as well as the deprojected density and pressure profiles, all show a sharp drop consistent with an outwardly-propagating shock front located at 40 arcmin, corresponding to the outermost edge of the giant radio halo observed at 352 MHz with the Westerbork Synthesis Radio Telescope. The shock front may be powering this radio emission. A clear entropy excess inside of r 500 reflects the violent merging events linked with these morphological features. Beyond r 500 , the entropy profiles of the Coma Cluster along the relatively relaxed directions are consistent with the power-law behavior expected from simple models of gravitational large-scale structure formation. The pressure is also in agreement at these radii with the expected values measured from Sunyaev-Zel'dovich data from the Planck satellite. However, due to the large uncertainties associated with the Coma Cluster measurements, we cannot yet exclude an entropy flattening in this system consistent with that seen in more relaxed cool core clusters

  5. Non-thermal pressure in the outskirts of Abell 2142

    Science.gov (United States)

    Fusco-Femiano, Roberto; Lapi, Andrea

    2018-03-01

    Clumping and turbulence are expected to affect the matter accreted on to the outskirts of galaxy clusters. To determine their impact on the thermodynamic properties of Abell 2142, we perform an analysis of the X-ray temperature data from XMM-Newton via our SuperModel, a state-of-the-art tool for investigating the astrophysics of the intracluster medium already tested on many individual clusters (since Cavaliere, Lapi & Fusco-Femiano 2009). Using the gas density profile corrected for clumpiness derived by Tchernin et al. (2016), we find evidence for the presence of a non-thermal pressure component required to sustain gravity in the cluster outskirts of Abell 2142, that amounts to about 30 per cent of the total pressure at the virial radius. The presence of the non-thermal component implies the gas fraction to be consistent with the universal value at the virial radius and the electron thermal pressure profile to be in good agreement with that inferred from the SZ data. Our results indicate that the presence of gas clumping and of a non-thermal pressure component are both necessary to recover the observed physical properties in the cluster outskirts. Moreover, we stress that an alternative method often exploited in the literature (included Abell 2142) to determine the temperature profile kBT = Pe/ne basing on a combination of the Sunyaev-Zel'dovich (SZ) pressure Pe and of the X-ray electron density ne does not allow us to highlight the presence of non-thermal pressure support in the cluster outskirts.

  6. The Effects of Ram Pressure on the Cold Clouds in the Centers of Galaxy Clusters

    Science.gov (United States)

    Li, Yuan; Ruszkowski, Mateusz; Tremblay, Grant

    2018-02-01

    We discuss the effect of ram pressure on the cold clouds in the centers of cool-core galaxy clusters, and in particular, how it reduces cloud velocity and sometimes causes an offset between the cold gas and young stars. The velocities of the molecular gas in both observations and our simulations fall in the range of 100–400 km s‑1, which is much lower than expected if they fall from a few tens of kiloparsecs ballistically. If the intracluster medium (ICM) is at rest, the ram pressure of the ICM only slightly reduces the velocity of the clouds. When we assume that the clouds are actually “fluffier” because they are co-moving with a warm-hot layer, the velocity becomes smaller. If we also consider the active galactic nucleus wind in the cluster center by adding a wind profile measured from the simulation, the clouds are further slowed down at small radii, and the resulting velocities are in general agreement with the observations and simulations. Because ram pressure only affects gas but not stars, it can cause a separation between a filament and young stars that formed in the filament as they move through the ICM together. This separation has been observed in Perseus and also exists in our simulations. We show that the star-filament offset, combined with line-of-sight velocity measurements, can help determine the true motion of the cold gas, and thus distinguish between inflows and outflows.

  7. Chameleonic contribution to the Sunyaev-Zel'dovich radial profile of the Coma cluster

    International Nuclear Information System (INIS)

    Davis, Anne-Christine; Schelpe, Camilla A. O.; Shaw, Douglas J.

    2011-01-01

    We constrain the chameleonic Sunyaev-Zel'dovich (CSZ) effect in the Coma cluster from measurements of the Coma radial profile presented in the WMAP 7-year results. The CSZ effect arises from the interaction of a scalar (or pseudoscalar) particle with the cosmic microwave background in the magnetic field of galaxy clusters. We combine this radial profile data with SZ measurements towards the center of the Coma cluster in different frequency bands, to find ΔT SZ,RJ (0)=-410±50 μK and ΔT CSZ 204 GHz (0) > or approx. -50 μK (at 95% confidence) for the thermal SZ and CSZ effects in the cluster, respectively. This leads to an estimated bound on the photon to scalar (or pseudoscalar) coupling strength of g eff -10 GeV -1 .

  8. Compressor Research Facility F100 High Pressure Compressor Inlet Total Pressure and Swirl Profile Simulation.

    Science.gov (United States)

    1984-10-01

    1627 VANE ANGLE- U SCREE 4 S,,, L53 S 6 4 NSW, 153 Figure 139. Total Pressure Profile Figure 140. Total Pressure Profile (Phase III), PSV = 250 (Phase...STATION 2.5 , PT. 1-1574- 1585 VANE ANGLE- 15 PT. 0-IMB 8- 150 VANE ANGLE= 21SCREENS- 4 I 54 SDIENS-4 X L53 Figure 137. Total Pressure Profile Figure 138...A 53: if 1-4;2.A 54: for L-10 to 16;wrt 709,"ASVN5SOIVFIVSIVT3VS"for J-l to 5 *55: r!-’ 709,E[A,L,J);nex~t ,I-r~eXt f! *56: if 1-1;wrt 709," TD )"red

  9. Halo Pressure Profile through the Skew Cross-power Spectrum of the Sunyaev–Zel’dovich Effect and CMB Lensing in Planck

    Energy Technology Data Exchange (ETDEWEB)

    Timmons, Nicholas; Cooray, Asantha; Feng, Chang [Department of Physics and Astronomy, University of California, Irvine, CA 92697 (United States); Keating, Brian [Department of Physics, University of California, San Diego, La Jolla, CA 92093 (United States)

    2017-11-01

    We measure the cosmic microwave background (CMB) skewness power spectrum in Planck , using frequency maps of the HFI instrument and the Sunyaev–Zel’dovich (SZ) component map. The two-to-one skewness power spectrum measures the cross-correlation between CMB lensing and the thermal SZ effect. We also directly measure the same cross-correlation using the Planck CMB lensing map and the SZ map and compare it to the cross-correlation derived from the skewness power spectrum. We model fit the SZ power spectrum and CMB lensing–SZ cross-power spectrum via the skewness power spectrum to constrain the gas pressure profile of dark matter halos. The gas pressure profile is compared to existing measurements in the literature including a direct estimate based on the stacking of SZ clusters in Planck .

  10. A study of the pressure profiles near the first pumping aperture in a high pressure photoelectron spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Kahk, J. Matthias; Villar-Garcia, Ignacio J. [Department of Materials, Imperial College London, Exhibition Road, London SW7 2AZ (United Kingdom); Grechy, Lorenza; Bruce, Paul J.K.; Vincent, Peter E. [Department of Aeronautics, Imperial College London, London SW7 2AZ (United Kingdom); Eriksson, Susanna K. [Department of Chemistry-Ångström, Uppsala University, Box 523, 751 20 Uppsala (Sweden); Rensmo, Håkan; Hahlin, Maria [Department of Physics and Astronomy, Uppsala University, Box 516, 751 20 Uppsala (Sweden); Åhlund, John; Edwards, Mårten O.M. [VG Scienta AB, Box 15120, 750 15 Uppsala (Sweden); Payne, David J., E-mail: d.payne@imperial.ac.uk [Department of Materials, Imperial College London, Exhibition Road, London SW7 2AZ (United Kingdom)

    2015-11-15

    Highlights: • We have examined pressure variations in a high pressure photoelectron spectrometer. • Pressure profiles have been simulated using computational fluid dynamics modelling. • The results are useful for determining the optimal sample position for measurements. - Abstract: In a high-pressure photoelectron spectrometer, the sample is positioned close to a differential pumping aperture, behind which the pressure is several orders of magnitude lower than the pressure in the analysis chamber. To find the optimal sample position, where the path length of the photoelectrons through the high pressure region is minimized as far as possible without compromising knowledge of the actual pressure at the sample surface, an understanding of the pressure variations near the sample and the aperture is required. A computational fluid dynamics study has been carried out to examine the pressure profiles, and the results are compared against experimental spectra whose intensities are analyzed using the Beer–Lambert law. The resultant pressure profiles are broadly similar to the one previously derived from a simplistic molecular flow model, but indicate that as the pressure in the analysis chamber is raised, the region over which the pressure drop occurs becomes progressively narrower.

  11. A study of the pressure profiles near the first pumping aperture in a high pressure photoelectron spectrometer

    International Nuclear Information System (INIS)

    Kahk, J. Matthias; Villar-Garcia, Ignacio J.; Grechy, Lorenza; Bruce, Paul J.K.; Vincent, Peter E.; Eriksson, Susanna K.; Rensmo, Håkan; Hahlin, Maria; Åhlund, John; Edwards, Mårten O.M.; Payne, David J.

    2015-01-01

    Highlights: • We have examined pressure variations in a high pressure photoelectron spectrometer. • Pressure profiles have been simulated using computational fluid dynamics modelling. • The results are useful for determining the optimal sample position for measurements. - Abstract: In a high-pressure photoelectron spectrometer, the sample is positioned close to a differential pumping aperture, behind which the pressure is several orders of magnitude lower than the pressure in the analysis chamber. To find the optimal sample position, where the path length of the photoelectrons through the high pressure region is minimized as far as possible without compromising knowledge of the actual pressure at the sample surface, an understanding of the pressure variations near the sample and the aperture is required. A computational fluid dynamics study has been carried out to examine the pressure profiles, and the results are compared against experimental spectra whose intensities are analyzed using the Beer–Lambert law. The resultant pressure profiles are broadly similar to the one previously derived from a simplistic molecular flow model, but indicate that as the pressure in the analysis chamber is raised, the region over which the pressure drop occurs becomes progressively narrower.

  12. THE ROLE OF RAM PRESSURE STRIPPING IN THE QUENCHING OF CLUSTER STAR FORMATION

    International Nuclear Information System (INIS)

    Book, Laura G.; Benson, Andrew J.

    2010-01-01

    Recent observations of galaxy clusters have shown that environmental effects apparently associated with the cluster begin to lower the star formation rates of galaxies at distances as great as three times the cluster virial radius. These observations may indicate preprocessing of cluster galaxies in groups or in the cluster core for galaxies on highly elliptical orbits, but may also imply that the environmental effects due to the cluster are directly affecting galaxies on their first infall. To explore these issues, we investigate different models of ram pressure stripping (RPS) as it acts on satellite galaxies in clusters and compare to observations of the radial star formation gradient in clusters. We calculate the location of the accretion shock around model clusters and use this as the radius of onset of RPS in the GALFORM semi-analytic model of galaxy formation. Comparison of the results of our model and previously considered, simpler ram pressure models with recent observations indicates that current data are unable to strongly discriminate between models of RPS due to the complex interplay of preprocessing effects at work. However, future observations of a larger sample of clusters will likely be able to place stronger constraints on the process of RPS and its role in shaping radial trends in and around clusters.

  13. Ionized-cluster source based on high-pressure corona discharge

    International Nuclear Information System (INIS)

    Lokuliyanage, K.; Huber, D.; Zappa, F.; Scheier, P.

    2006-01-01

    Full text: It has been demonstrated that energetic beams of large clusters, with thousands of atoms, can be a powerful tool for surface modification. Normally ionized cluster beams are obtained by electron impact on neutral beams produced in a supersonic expansion. At the University of Innsbruck we are pursuing the realization of a high current cluster ion source based on the corona discharge.The idea in the present case is that the ionization should occur prior to the supersonic expansion, thus supersede the need of subsequent electron impact. In this contribution we present the project of our source in its initial stage. The intensity distribution of cluster sizes as a function of the source parameters, such as input pressure, temperature and gap voltage, are investigated with the aid of a custom-built time of flight mass spectrometer. (author)

  14. Mass Profile Decomposition of the Frontier Fields Cluster MACS J0416-2403: Insights on the Dark-matter Inner Profile

    Science.gov (United States)

    Annunziatella, M.; Bonamigo, M.; Grillo, C.; Mercurio, A.; Rosati, P.; Caminha, G.; Biviano, A.; Girardi, M.; Gobat, R.; Lombardi, M.; Munari, E.

    2017-12-01

    We present a high-resolution dissection of the two-dimensional total mass distribution in the core of the Hubble Frontier Fields galaxy cluster MACS J0416.1‑2403, at z = 0.396. We exploit HST/WFC3 near-IR (F160W) imaging, VLT/Multi Unit Spectroscopic Explorer spectroscopy, and Chandra data to separate the stellar, hot gas, and dark-matter mass components in the inner 300 kpc of the cluster. We combine the recent results of our refined strong lensing analysis, which includes the contribution of the intracluster gas, with the modeling of the surface brightness and stellar mass distributions of 193 cluster members, of which 144 are spectroscopically confirmed. We find that, moving from 10 to 300 kpc from the cluster center, the stellar to total mass fraction decreases from 12% to 1% and the hot gas to total mass fraction increases from 3% to 9%, resulting in a baryon fraction of approximatively 10% at the outermost radius. We measure that the stellar component represents ∼30%, near the cluster center, and 15%, at larger clustercentric distances, of the total mass in the cluster substructures. We subtract the baryonic mass component from the total mass distribution and conclude that within 30 kpc (∼3 times the effective radius of the brightest cluster galaxy) from the cluster center the surface mass density profile of the total mass and global (cluster plus substructures) dark-matter are steeper and that of the diffuse (cluster) dark-matter is shallower than an NFW profile. Our current analysis does not point to a significant offset between the cluster stellar and dark-matter components. This detailed and robust reconstruction of the inner dark-matter distribution in a larger sample of galaxy clusters will set a new benchmark for different structure formation scenarios.

  15. Using Self-Organizing Map (SOM) Clusters of Ozonesonde Profiles to Evaluate Climatologies and Create Linkages between Meteorology and Pollution

    Science.gov (United States)

    Stauffer, R. M.; Thompson, A. M.; Young, G. S.; Oltmans, S. J.; Johnson, B.

    2016-12-01

    Ozone (O3) climatologies are typically created by averaging ozonesonde profiles on a monthly or seasonal basis, either for specific regions or zonally. We demonstrate the advantages of using a statistical clustering technique, self-organizing maps (SOM), over this simple averaging, through analysis of more than 4500 sonde profiles taken from the long-term US sites at Boulder, CO; Huntsville, AL; Trinidad Head, CA; and Wallops Island, VA. First, we apply SOM to O3 mixing ratios from surface to 12 km amsl. At all four sites, profiles in SOM clusters exhibit similar tropopause height, 500 hPa height and temperature, and total and tropospheric column O3. Second, when profiles from each SOM cluster are compared to monthly O3 means, near-tropopause O3 in three of the clusters is double (over +100 ppbv) the climatological O3 mixing ratio. The three clusters include 13-16% of all profiles, mostly from winter and spring. Large mid-tropospheric deviations from monthly means are found in two highly-populated clusters that represent either distinctly polluted (summer) or clean O3 (fall-winter, high tropopause) profiles. Thus, SOM indeed appear to represent US O3 profile statistics better than conventional climatologies. In the case of Trinidad Head, SOM clusters of O3 profile data from the lower troposphere (surface-6 km amsl) can discriminate background vs polluted O3 and the meteorology associated with each. Two of nine O3 clusters exhibit thin layers ( 100s of m thick) of high O3, typically between 1 and 4 km. Comparisons between clusters and downwind, high-altitude surface O3 measurements display a marked impact of the elevated tropospheric O­­3. Days corresponding to the high O3 clusters exhibit hourly surface O3 anomalies at surface sites of +5 -10 ppbv compared to a climatology; the anomalies can last up to four days. We also explore applications of SOM to tropical ozonesonde profiles, where tropospheric O3 variability is generally smaller.

  16. Integration K-Means Clustering Method and Elbow Method For Identification of The Best Customer Profile Cluster

    Science.gov (United States)

    Syakur, M. A.; Khotimah, B. K.; Rochman, E. M. S.; Satoto, B. D.

    2018-04-01

    Clustering is a data mining technique used to analyse data that has variations and the number of lots. Clustering was process of grouping data into a cluster, so they contained data that is as similar as possible and different from other cluster objects. SMEs Indonesia has a variety of customers, but SMEs do not have the mapping of these customers so they did not know which customers are loyal or otherwise. Customer mapping is a grouping of customer profiling to facilitate analysis and policy of SMEs in the production of goods, especially batik sales. Researchers will use a combination of K-Means method with elbow to improve efficient and effective k-means performance in processing large amounts of data. K-Means Clustering is a localized optimization method that is sensitive to the selection of the starting position from the midpoint of the cluster. So choosing the starting position from the midpoint of a bad cluster will result in K-Means Clustering algorithm resulting in high errors and poor cluster results. The K-means algorithm has problems in determining the best number of clusters. So Elbow looks for the best number of clusters on the K-means method. Based on the results obtained from the process in determining the best number of clusters with elbow method can produce the same number of clusters K on the amount of different data. The result of determining the best number of clusters with elbow method will be the default for characteristic process based on case study. Measurement of k-means value of k-means has resulted in the best clusters based on SSE values on 500 clusters of batik visitors. The result shows the cluster has a sharp decrease is at K = 3, so K as the cut-off point as the best cluster.

  17. GASP. IX. Jellyfish galaxies in phase-space: an orbital study of intense ram-pressure stripping in clusters

    Science.gov (United States)

    Jaffé, Yara L.; Poggianti, Bianca M.; Moretti, Alessia; Gullieuszik, Marco; Smith, Rory; Vulcani, Benedetta; Fasano, Giovanni; Fritz, Jacopo; Tonnesen, Stephanie; Bettoni, Daniela; Hau, George; Biviano, Andrea; Bellhouse, Callum; McGee, Sean

    2018-06-01

    It is well known that galaxies falling into clusters can experience gas stripping due to ram pressure by the intra-cluster medium. The most spectacular examples are galaxies with extended tails of optically bright stripped material known as `jellyfish'. We use the first large homogeneous compilation of jellyfish galaxies in clusters from the WINGS and OmegaWINGS surveys, and follow-up MUSE observations from the GASP MUSE programme to investigate the orbital histories of jellyfish galaxies in clusters and reconstruct their stripping history through position versus velocity phase-space diagrams. We construct analytic models to define the regions in phase-space where ram-pressure stripping is at play. We then study the distribution of cluster galaxies in phase-space and find that jellyfish galaxies have on average higher peculiar velocities (and higher cluster velocity dispersion) than the overall population of cluster galaxies at all cluster-centric radii, which is indicative of recent infall into the cluster and radial orbits. In particular, the jellyfish galaxies with the longest gas tails reside very near the cluster cores (in projection) and are moving at very high speeds, which coincides with the conditions of the most intense ram pressure. We conclude that many of the jellyfish galaxies seen in clusters likely formed via fast (˜1-2 Gyr), incremental, outside-in ram-pressure stripping during first infall into the cluster in highly radial orbits.

  18. Maximum-likelihood model averaging to profile clustering of site types across discrete linear sequences.

    Directory of Open Access Journals (Sweden)

    Zhang Zhang

    2009-06-01

    Full Text Available A major analytical challenge in computational biology is the detection and description of clusters of specified site types, such as polymorphic or substituted sites within DNA or protein sequences. Progress has been stymied by a lack of suitable methods to detect clusters and to estimate the extent of clustering in discrete linear sequences, particularly when there is no a priori specification of cluster size or cluster count. Here we derive and demonstrate a maximum likelihood method of hierarchical clustering. Our method incorporates a tripartite divide-and-conquer strategy that models sequence heterogeneity, delineates clusters, and yields a profile of the level of clustering associated with each site. The clustering model may be evaluated via model selection using the Akaike Information Criterion, the corrected Akaike Information Criterion, and the Bayesian Information Criterion. Furthermore, model averaging using weighted model likelihoods may be applied to incorporate model uncertainty into the profile of heterogeneity across sites. We evaluated our method by examining its performance on a number of simulated datasets as well as on empirical polymorphism data from diverse natural alleles of the Drosophila alcohol dehydrogenase gene. Our method yielded greater power for the detection of clustered sites across a breadth of parameter ranges, and achieved better accuracy and precision of estimation of clusters, than did the existing empirical cumulative distribution function statistics.

  19. Farmer Performance under Competitive Pressure in Agro-cluster Regions

    NARCIS (Netherlands)

    Wardhana, D.; Ihle, R.; Heijman, W.J.M.

    2017-01-01

    Agro-clusters would allow farmers to acquire positive and negative externalities. On one hand, smallholder farmers in spatial proximity are likely to benefit from this concentration; on the other hand, they incur high competitive pressure from other neighboring farmers. We examine the link between

  20. Lateral pressure profiles in lipid monolayers

    NARCIS (Netherlands)

    Baoukina, Svetlana; Marrink, Siewert J.; Tieleman, D. Peter

    2010-01-01

    We have used molecular dynamics simulations with coarse-grained and atomistic models to study the lateral pressure profiles in lipid monolayers. We first consider simple oil/air and oil/water interfaces, and then proceed to lipid monolayers at air/water and oil/water interfaces. The results are

  1. Link between self-consistent pressure profiles and electron internal transport barriers in tokamaks

    Energy Technology Data Exchange (ETDEWEB)

    Razumova, K A [Nuclear Fusion Institute, RRC ' Kurchatov Institute' , 123182 Moscow (Russian Federation); Andreev, V F [Nuclear Fusion Institute, RRC ' Kurchatov Institute' , 123182 Moscow (Russian Federation); Donne, A J H [FOM-Institute for Plasma Physics Rijnhuizen, Association EURATOM-FOM, partner in the Trilateral Euregio Cluster, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Hogeweij, G M D [FOM-Institute for Plasma Physics Rijnhuizen, Association EURATOM-FOM, partner in the Trilateral Euregio Cluster, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Lysenko, S E [Nuclear Fusion Institute, RRC ' Kurchatov Institute' , 123182 Moscow (Russian Federation); Shelukhin, D A [Nuclear Fusion Institute, RRC ' Kurchatov Institute' , 123182 Moscow (Russian Federation); Spakman, G W [FOM-Institute for Plasma Physics Rijnhuizen, Association EURATOM-FOM, partner in the Trilateral Euregio Cluster, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Vershkov, V A [Nuclear Fusion Institute, RRC ' Kurchatov Institute' , 123182 Moscow (Russian Federation); Zhuravlev, V A [Nuclear Fusion Institute, RRC ' Kurchatov Institute' , 123182 Moscow (Russian Federation)

    2006-09-15

    Tokamak plasmas have a tendency to self-organization: the plasma pressure profiles obtained in different operational regimes and even in various tokamaks may be represented by a single typical curve, called the self-consistent pressure profile. About a decade ago local zones with enhanced confinement were discovered in tokamak plasmas. These zones are referred to as internal transport barriers (ITBs) and they can act on the electron and/or ion fluid. Here the pressure gradients can largely exceed the gradients dictated by profile consistency. So the existence of ITBs seems to be in contradiction with the self-consistent pressure profiles (this is also often referred to as profile resilience or profile stiffness). In this paper we will discuss the interplay between profile consistency and ITBs. A summary of the cumulative information obtained from T-10, RTP and TEXTOR is given, and a coherent explanation of the main features of the observed phenomena is suggested. Both phenomena, the self-consistent profile and ITB, are connected with the density of rational magnetic surfaces, where the turbulent cells are situated. The distance between these cells determines the level of their interaction, and therefore the level of the turbulent transport. This process regulates the plasma pressure profile. If the distance is wide, the turbulent flux may be diminished and the ITB may be formed. In regions with rarefied surfaces the steeper pressure gradients are possible without instantaneously inducing pressure driven instabilities, which force the profiles back to their self-consistent shapes. Also it can be expected that the ITB region is wider for lower dq/d{rho} (more rarefied surfaces)

  2. MEASUREMENT OF THE HALO BIAS FROM STACKED SHEAR PROFILES OF GALAXY CLUSTERS

    Energy Technology Data Exchange (ETDEWEB)

    Covone, Giovanni [Dipartimento di Fisica, Università di Napoli " Federico II," Via Cinthia, I-80126 Napoli (Italy); Sereno, Mauro [Dipartimento di Fisica e Astronomia, Università di Bologna, Viale Berti Pichat 6/2, I-40127 Bologna (Italy); Kilbinger, Martin [CEA/Irfu/SAp Saclay, Laboratoire AIM, F-91191 Gif-sur-Yvette (France); Cardone, Vincenzo F. [I.N.A.F.-Osservatorio Astronomico di Roma, Via Frascati 33, I-00040 Monteporzio Catone (Roma) (Italy)

    2014-04-01

    We present observational evidence of the two-halo term in the stacked shear profile of a sample of ∼1200 optically selected galaxy clusters based on imaging data and the public shear catalog from the CFHTLenS. We find that the halo bias, a measure of the correlated distribution of matter around galaxy clusters, has amplitude and correlation with galaxy cluster mass in very good agreement with the predictions based on the LCDM standard cosmological model. The mass-concentration relation is flat but higher than theoretical predictions. We also confirm the close scaling relation between the optical richness of galaxy clusters and their mass.

  3. A Universal Velocity Dispersion Profile for Pressure Supported Systems: Evidence for MONDian Gravity across Seven Orders of Magnitude in Mass

    Energy Technology Data Exchange (ETDEWEB)

    Durazo, R.; Hernandez, X.; Sánchez, S. F. [Instituto de Astronomía, Universidad Nacional Autónoma de México, Apartado Postal 70-264 C.P. 04510 México D.F., México (Mexico); Sodi, B. Cervantes [Instituto de Radioastronomía y Astrofísica, Universidad Nacional Autónoma de México, Campus Morelia, A.P. 3-72, C.P. 58089 Michoacán, México (Mexico)

    2017-03-10

    For any MONDian extended theory of gravity where the rotation curves of spiral galaxies are explained through a change in physics rather than the hypothesis of dark matter, a generic dynamical behavior is expected for pressure supported systems: an outer flattening of the velocity dispersion profile occurring at a characteristic radius, where both the amplitude of this flat velocity dispersion and the radius at which it appears are predicted to show distinct scalings with the total mass of the system. By carefully analyzing the dynamics of globular clusters and elliptical galaxies, we are able to significantly extend the astronomical diversity of objects in which MONDian gravity has been tested, from spiral galaxies to the much larger mass range covered by pressure supported systems. We show that a universal projected velocity dispersion profile accurately describes various classes of pressure supported systems, and further, that the expectations of extended gravity are met across seven orders of magnitude in mass. These observed scalings are not expected under dark matter cosmology, and would require particular explanations tuned at the scales of each distinct astrophysical system.

  4. CLASH-VLT: testing the nature of gravity with galaxy cluster mass profiles

    Energy Technology Data Exchange (ETDEWEB)

    Pizzuti, L.; Sartoris, B.; Borgani, S.; Girardi, M. [Dipartimento di Fisica, Sezione di Astronomia, Università di Trieste, Via Tiepolo 11, I-34143 Trieste (Italy); Amendola, L. [Institut für Theoretische Physik, Universität Heidelberg, Philosophenweg 16, D-69120 Heidelberg (Germany); Umetsu, K. [5 Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 10617, Taiwan (China); Biviano, A.; Balestra, I.; Nonino, M. [INAF—Osservatorio Astronomico di Trieste, Via Tiepolo 11, I-34143 Trieste (Italy); Rosati, P. [University Observatory Munich, Scheinerstrasse 1, D-81679 Mu\\' nchen (Germany); Caminha, G.B. [Dipartimento di Fisica e Scienze della Terra, Università di Ferrara, Via Saragat 1, I-44122 Ferrara (Italy); Frye, B. [Steward Observatory/Department of Astronomy, University of Arizona, 933 N Cherry Ave, Tucson, AZ 85721 (United States); Koekemoer, A. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Grillo, C. [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen (Denmark); Lombardi, M. [Dipartimento di Fisica, Università degli Studi di Milano, via Celoria 16, I-20133 Milan (Italy); Mercurio, A., E-mail: pizzuti@oats.inaf.it, E-mail: barbara.sartoris@gmail.com, E-mail: borgani@oats.inaf.it, E-mail: l.amendola@thphys.uniheidelberg.de [Osservatorio Astronomico di Capodimonte, Via Moiariello 16, I-80131 Napoli (Italy)

    2016-04-01

    We use high-precision kinematic and lensing measurements of the total mass profile of the dynamically relaxed galaxy cluster MACS J1206.2-0847 at z=0.44 to estimate the value of the ratio η=Ψ/Φ between the two scalar potentials in the linear perturbed Friedmann-Lemaitre-Robertson-Walker metric. An accurate measurement of this ratio, called anisotropic stress, could show possible, interesting deviations from the predictions of the theory of General Relativity, according to which Ψ should be equal to Φ. Complementary kinematic and lensing mass profiles were derived from exhaustive analyses using the data from the Cluster Lensing And Supernova survey with Hubble (CLASH) and the spectroscopic follow-up with the Very Large Telescope (CLASH-VLT). Whereas the kinematic mass profile tracks only the time-time part of the perturbed metric (i.e. only Φ), the lensing mass profile reflects the contribution of both time-time and space-space components (i.e. the sum Φ+Ψ). We thus express η as a function of the mass profiles and perform our analysis over the radial range 0.5 Mpc≤ r≤ r{sub 200}=1.96 Mpc. Using a spherical Navarro-Frenk-White mass profile, which well fits the data, we obtain η(r{sub 200})=1.01 {sub −0.28}{sup +0.31} at the 68% C.L. We discuss the effect of assuming different functional forms for mass profiles and of the orbit anisotropy in the kinematic reconstruction. Interpreting this result within the well-studied f(R) modified gravity model, the constraint on η translates into an upper bound to the interaction length (inverse of the scalaron mass) smaller than 2 Mpc. This tight constraint on the f(R) interaction range is however substantially relaxed when systematic uncertainties in the analysis are considered. Our analysis highlights the potential of this method to detect deviations from general relativity, while calling for the need of further high-quality data on the total mass distribution of clusters and improved control on systematic

  5. Cluster analysis of residential heat load profiles and the role of technical and household characteristics

    DEFF Research Database (Denmark)

    Carmo, Carolina; Christensen, Toke Haunstrup

    2016-01-01

    of the temporality of the energy demand is needed. This paper contributes to this by focusing on the daily load profiles of energy demand for heating of Danish dwellings with heat pumps. Based on hourly recordings from 139 dwellings and employing cluster and regression analysis, the paper explores patterns...... (typologies) in daily heating load profiles and how these relate to socio-economic and technical characteristics of the included households. The study shows that the load profiles vary according to the external load conditions. Two main clusters were identified for both weekdays and weekends and across load...

  6. In-clustering effects in InAlN and InGaN revealed by high pressure studies

    DEFF Research Database (Denmark)

    Gorczyca, I.; Suski, T.; Kaminska, A.

    2010-01-01

    results are compared with the results of photoluminescence measurements performed at high hydrostatic pressures on InAlN and InGaN quasi-bulk epilayers. We discuss the modification of the uppermost valence band due to formation of In clusters which, together with the related lattice relaxations, may......Electronic band structure calculations of InAlN and InGaN under pressure are presented for two different arrangements of the In atoms, uniform and clustered. The band gap pressure coefficients exhibit strong bowing, and the effect is especially large when indium atoms are clustered. The theoretical...

  7. Identifying the ideal profile of French yogurts for different clusters of consumers.

    Science.gov (United States)

    Masson, M; Saint-Eve, A; Delarue, J; Blumenthal, D

    2016-05-01

    Identifying the sensory properties that affect consumer preferences for food products is an important feature of product development. Different methods, such as external preference mapping or partial least squares regression, are used to establish relationships between sensory data and consumer preferences and to identify sensory attributes that drive consumer preferences, by highlighting optimum products. Plain French yogurts were evaluated by a sensory profiling method performed by 12 trained judges. In parallel, 180 consumers were asked to score their overall liking and complete a cognitive restraint questionnaire. After hierarchical cluster analysis on the liking scores, preference mapping using a quadratic regression model was performed. Five clusters of consumers were identified as a function of different preference patterns. Contrary to our expectations, fat levels were not discriminating. For each cluster, the results of preference mapping enabled the identification of optimum products. A comparison of the 5 sensory profiles revealed numerous differences between key sensory attributes. For example, one consumer cluster had a strong preference for products perceived as very thick, grainy, but with a less flowing texture, less sticky, whey presence and color, in contrast to other clusters. In addition, each segment of consumers was characterized according to the results of the cognitive restraint questionnaire. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  8. The dysregulated cluster in personality profiling research: Longitudinal stability and associations with bulimic behaviors and correlates

    Science.gov (United States)

    Slane, Jennifer D.; Klump, Kelly L.; Donnellan, M. Brent; McGue, Matthew; Iacono, William G.

    2013-01-01

    Among cluster analytic studies of the personality profiles associated with bulimia nervosa, a group of individuals characterized by emotional lability and behavioral dysregulation (i.e., a dysregulated cluster) has emerged most consistently. However, previous studies have all been cross-sectional and mostly used clinical samples. This study aimed to replicate associations between the dysregulated personality cluster and bulimic symptoms and related characteristics using a longitudinal, population-based sample. Participants were females assessed at ages 17 and 25 from the Minnesota Twin Family Study, clustered based on their personality traits. The Dysregulated cluster was successfully identified at both time points and was more stable across time than either the Resilient or Sensation Seeking clusters. Rates of bulimic symptoms and related behaviors (e.g., alcohol use problems) were also highest in the dysregulated group. Findings suggest that the dysregulated cluster is a relatively stable and robust profile that is associated with bulimic symptoms. PMID:23398096

  9. Investigating the Correspondence Between Transcriptomic and Proteomic Expression Profiles Using Coupled Cluster Models

    International Nuclear Information System (INIS)

    Rogers, Simon; Girolami, Mark; Kolch, Walter; Waters, Katrina M.; Liu, Tao; Thrall, Brian D.; Wiley, H. S.

    2008-01-01

    Modern transcriptomics and proteomics enable us to survey the expression of RNAs and proteins at large scales. While these data are usually generated and analyzed separately, there is an increasing interest in comparing and co-analyzing transcriptome and proteome expression data. A major open question is whether transcriptome and proteome expression is linked and how it is coordinated. Results: Here we have developed a probabilistic clustering model that permits analysis of the links between transcriptomic and proteomic profiles in a sensible and flexible manner. Our coupled mixture model defines a prior probability distribution over the component to which a protein profile should be assigned conditioned on which component the associated mRNA profile belongs to. By providing probabilistic assignments this approach sits between the two extremes of concatenating the data on the assumption that mRNA and protein clusters would have a one-to-one relationship, and independent clustering where the mRNA profile provides no information on the protein profile and vice-versa. We apply this approach to a large dataset of quantitative transcriptomic and proteomic expression data obtained from a human breast epithelial cell line (HMEC) stimulated by epidermal growth factor (EGF) over a series of timepoints corresponding to one cell cycle. The results reveal a complex relationship between transcriptome and proteome with most mRNA clusters linked to at least two protein clusters, and vice versa. A more detailed analysis incorporating information on gene function from the gene ontology database shows that a high correlation of mRNA and protein expression is limited to the components of some molecular machines, such as the ribosome, cell adhesion complexes and the TCP-1 chaperonin involved in protein folding. Conclusions: The dynamic regulation of the transcriptome and proteome in mammalian cells in response to an acute mitogenic stimulus appears largely independent with very little

  10. Student profiling on university co-curricular activities using cluster analysis

    Science.gov (United States)

    Rajenthran, Hemabegai A./P.; Shaharanee, Izwan Nizal Mohd; Jamil, Jastini Mohd.

    2017-11-01

    In higher learning institutions, the co-curricular programs are needed for the graduation besides the standard academic programs. By actively participating in co-curricular, students can attain many of soft skills and proficiencies besides learning and adopting campus environment, community and traditions. Co-curricular activities are implemented by universities mainly for the refinement of the academic achievement along with the social development. This studies aimed to analyse the academic profile of the co-curricular students among uniform units. The main objective of study is to develop a profile of student co-curricular activities in uniform units. Additionally, several variables has been selected to serve as the characteristics for student co-curricular profile. The findings of this study demonstrate the practicality of clustering technique to investigate student's profiles and allow for a better understanding of student's behavior and co-curriculum activities.

  11. Clinical Implications of Cluster Analysis-Based Classification of Acute Decompensated Heart Failure and Correlation with Bedside Hemodynamic Profiles.

    Directory of Open Access Journals (Sweden)

    Tariq Ahmad

    Full Text Available Classification of acute decompensated heart failure (ADHF is based on subjective criteria that crudely capture disease heterogeneity. Improved phenotyping of the syndrome may help improve therapeutic strategies.To derive cluster analysis-based groupings for patients hospitalized with ADHF, and compare their prognostic performance to hemodynamic classifications derived at the bedside.We performed a cluster analysis on baseline clinical variables and PAC measurements of 172 ADHF patients from the ESCAPE trial. Employing regression techniques, we examined associations between clusters and clinically determined hemodynamic profiles (warm/cold/wet/dry. We assessed association with clinical outcomes using Cox proportional hazards models. Likelihood ratio tests were used to compare the prognostic value of cluster data to that of hemodynamic data.We identified four advanced HF clusters: 1 male Caucasians with ischemic cardiomyopathy, multiple comorbidities, lowest B-type natriuretic peptide (BNP levels; 2 females with non-ischemic cardiomyopathy, few comorbidities, most favorable hemodynamics; 3 young African American males with non-ischemic cardiomyopathy, most adverse hemodynamics, advanced disease; and 4 older Caucasians with ischemic cardiomyopathy, concomitant renal insufficiency, highest BNP levels. There was no association between clusters and bedside-derived hemodynamic profiles (p = 0.70. For all adverse clinical outcomes, Cluster 4 had the highest risk, and Cluster 2, the lowest. Compared to Cluster 4, Clusters 1-3 had 45-70% lower risk of all-cause mortality. Clusters were significantly associated with clinical outcomes, whereas hemodynamic profiles were not.By clustering patients with similar objective variables, we identified four clinically relevant phenotypes of ADHF patients, with no discernable relationship to hemodynamic profiles, but distinct associations with adverse outcomes. Our analysis suggests that ADHF classification using

  12. Ensemble attribute profile clustering: discovering and characterizing groups of genes with similar patterns of biological features

    Directory of Open Access Journals (Sweden)

    Bissell MJ

    2006-03-01

    Full Text Available Abstract Background Ensemble attribute profile clustering is a novel, text-based strategy for analyzing a user-defined list of genes and/or proteins. The strategy exploits annotation data present in gene-centered corpora and utilizes ideas from statistical information retrieval to discover and characterize properties shared by subsets of the list. The practical utility of this method is demonstrated by employing it in a retrospective study of two non-overlapping sets of genes defined by a published investigation as markers for normal human breast luminal epithelial cells and myoepithelial cells. Results Each genetic locus was characterized using a finite set of biological properties and represented as a vector of features indicating attributes associated with the locus (a gene attribute profile. In this study, the vector space models for a pre-defined list of genes were constructed from the Gene Ontology (GO terms and the Conserved Domain Database (CDD protein domain terms assigned to the loci by the gene-centered corpus LocusLink. This data set of GO- and CDD-based gene attribute profiles, vectors of binary random variables, was used to estimate multiple finite mixture models and each ensuing model utilized to partition the profiles into clusters. The resultant partitionings were combined using a unanimous voting scheme to produce consensus clusters, sets of profiles that co-occured consistently in the same cluster. Attributes that were important in defining the genes assigned to a consensus cluster were identified. The clusters and their attributes were inspected to ascertain the GO and CDD terms most associated with subsets of genes and in conjunction with external knowledge such as chromosomal location, used to gain functional insights into human breast biology. The 52 luminal epithelial cell markers and 89 myoepithelial cell markers are disjoint sets of genes. Ensemble attribute profile clustering-based analysis indicated that both lists

  13. Methodological problems in pressure profile calculations for lipid bilayers

    DEFF Research Database (Denmark)

    Sonne, Jacob; Hansen, Flemming Yssing; Peters, Günther H.J.

    2005-01-01

    calculations: The first problem is that the pressure profile is not uniquely defined since the expression for the local pressure involves an arbitrary choice of an integration contour. We have investigated two different choices leading to the Irving-Kirkwood (IK) and Harasima (H) expressions for the local...

  14. Time-resolved wave profile measurements in copper to Megabar pressures

    Energy Technology Data Exchange (ETDEWEB)

    Chhabildas, L C; Asay, J R

    1981-01-01

    Many time-resolved techniques have been developed which have greatly aided in the understanding of dynamic material behavior such as the high pressure-dynamic strength of materials. In the paper, time-resolved measurements of copper (at shock-induced high pressures and temperatures) are used to illustrate the capability of using such techniques to investigate high pressure strength. Continuous shock loading and release wave profiles have been made in copper to 93 GPa using velocity interferometric techniques. Fine structure in the release wave profiles from the shocked state indicates an increase in shear strength of copper to 1.5 GPa at 93 GPa from its ambient value of 0.08 GPa.

  15. The Sensitivity Analysis of Axial Pressure Tube Creep Profile for Dryout Power in PHWR

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Euiseung; Kim, Youngae [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    The Stern Laboratory performed the CHF tests with only one axial pressure tube creep profile per 3.3%, 5.1% peak crept channel and made CHF correlation including creep factor from the CHF test results. Wolsong nuclear power plants also have utilized the same CHF correlation derived by CNL. Pressure tube diameter creep rate is function of fast neutron, coolant temperature, and coolant pressure in a channel. It means that various axial pressure tube creep profiles exist in PHWR due to the history of operating conditions. Usually, CHF correlation is used during ROP(Regional Overpower Protection) Trip Setpoint Analysis or Safety Analysis in PHWR. The sensitivity analysis for CHF effects using various creep profiles is needed. This paper summarizes the comparison results of dryout power between CHF test creep profile and estimated creep profiles of Wolsong units. The effect of axial pressure tube creep profile for dryout power in fuel channel is evaluated by using Stern Lab. CHF test creep profile and 380 channel creep profiles of Wolsong. The dryout powers at 3.3% and 5.1% test conditions are slightly smaller when using 380 Wolsong channels creep profiles. These also show that the simulated dryout powers maintain consistency regardless of flow conditions.

  16. UQlust: combining profile hashing with linear-time ranking for efficient clustering and analysis of big macromolecular data.

    Science.gov (United States)

    Adamczak, Rafal; Meller, Jarek

    2016-12-28

    Advances in computing have enabled current protein and RNA structure prediction and molecular simulation methods to dramatically increase their sampling of conformational spaces. The quickly growing number of experimentally resolved structures, and databases such as the Protein Data Bank, also implies large scale structural similarity analyses to retrieve and classify macromolecular data. Consequently, the computational cost of structure comparison and clustering for large sets of macromolecular structures has become a bottleneck that necessitates further algorithmic improvements and development of efficient software solutions. uQlust is a versatile and easy-to-use tool for ultrafast ranking and clustering of macromolecular structures. uQlust makes use of structural profiles of proteins and nucleic acids, while combining a linear-time algorithm for implicit comparison of all pairs of models with profile hashing to enable efficient clustering of large data sets with a low memory footprint. In addition to ranking and clustering of large sets of models of the same protein or RNA molecule, uQlust can also be used in conjunction with fragment-based profiles in order to cluster structures of arbitrary length. For example, hierarchical clustering of the entire PDB using profile hashing can be performed on a typical laptop, thus opening an avenue for structural explorations previously limited to dedicated resources. The uQlust package is freely available under the GNU General Public License at https://github.com/uQlust . uQlust represents a drastic reduction in the computational complexity and memory requirements with respect to existing clustering and model quality assessment methods for macromolecular structure analysis, while yielding results on par with traditional approaches for both proteins and RNAs.

  17. Observing RAM Pressure Stripping and Morphological Transformation in the Coma Cluster

    Science.gov (United States)

    Gregg, Michael; West, Michael

    2017-07-01

    The two largest spirals in the Coma cluster, NGC4911 and NGC4921, are being vigorously ram-pressure stripped by the hot intracluster medium. Our HST ACS and WFC3 images have revealed galactic scale shock fronts, giant "Pillars of Creation", rivulets of dust, and spatially coherent star formation in these grand design spirals. We have now obtained HST WFC3 imaging of five additional large Coma spirals to search for and investigate the effects of ram pressure stripping across the wider cluster environment. The results are equally spectacular as the first two examples. The geometry of the interactions in some cases allows an estimation of the various time scales involved, including gas flows out of the disk leading to creation of the ICM, and the attendant triggered star formation in the galaxy disks. The global star formation patterns yield insights into the spatial and temporal ISM-ICM interactions driving cluster galaxy evolution and ultimately transforming morphologies from spiral to S0. These processes were much more common in the early Universe when the intergalactic and intracluster components were initially created from stripping and destruction of member galaxies.

  18. Somatosensory nociceptive characteristics differentiate subgroups in people with chronic low back pain: a cluster analysis.

    Science.gov (United States)

    Rabey, Martin; Slater, Helen; OʼSullivan, Peter; Beales, Darren; Smith, Anne

    2015-10-01

    The objectives of this study were to explore the existence of subgroups in a cohort with chronic low back pain (n = 294) based on the results of multimodal sensory testing and profile subgroups on demographic, psychological, lifestyle, and general health factors. Bedside (2-point discrimination, brush, vibration and pinprick perception, temporal summation on repeated monofilament stimulation) and laboratory (mechanical detection threshold, pressure, heat and cold pain thresholds, conditioned pain modulation) sensory testing were examined at wrist and lumbar sites. Data were entered into principal component analysis, and 5 component scores were entered into latent class analysis. Three clusters, with different sensory characteristics, were derived. Cluster 1 (31.9%) was characterised by average to high temperature and pressure pain sensitivity. Cluster 2 (52.0%) was characterised by average to high pressure pain sensitivity. Cluster 3 (16.0%) was characterised by low temperature and pressure pain sensitivity. Temporal summation occurred significantly more frequently in cluster 1. Subgroups were profiled on pain intensity, disability, depression, anxiety, stress, life events, fear avoidance, catastrophizing, perception of the low back region, comorbidities, body mass index, multiple pain sites, sleep, and activity levels. Clusters 1 and 2 had a significantly greater proportion of female participants and higher depression and sleep disturbance scores than cluster 3. The proportion of participants undertaking Low back pain, therefore, does not appear to be homogeneous. Pain mechanisms relating to presentations of each subgroup were postulated. Future research may investigate prognoses and interventions tailored towards these subgroups.

  19. Dual beam organic depth profiling using large argon cluster ion beams

    Science.gov (United States)

    Holzweber, M; Shard, AG; Jungnickel, H; Luch, A; Unger, WES

    2014-01-01

    Argon cluster sputtering of an organic multilayer reference material consisting of two organic components, 4,4′-bis[N-(1-naphthyl-1-)-N-phenyl- amino]-biphenyl (NPB) and aluminium tris-(8-hydroxyquinolate) (Alq3), materials commonly used in organic light-emitting diodes industry, was carried out using time-of-flight SIMS in dual beam mode. The sample used in this study consists of a ∽400-nm-thick NPB matrix with 3-nm marker layers of Alq3 at depth of ∽50, 100, 200 and 300 nm. Argon cluster sputtering provides a constant sputter yield throughout the depth profiles, and the sputter yield volumes and depth resolution are presented for Ar-cluster sizes of 630, 820, 1000, 1250 and 1660 atoms at a kinetic energy of 2.5 keV. The effect of cluster size in this material and over this range is shown to be negligible. © 2014 The Authors. Surface and Interface Analysis published by John Wiley & Sons Ltd. PMID:25892830

  20. Hydrostatic Chandra X-ray analysis of SPT-selected galaxy clusters - I. Evolution of profiles and core properties

    Science.gov (United States)

    Sanders, J. S.; Fabian, A. C.; Russell, H. R.; Walker, S. A.

    2018-02-01

    We analyse Chandra X-ray Observatory observations of a set of galaxy clusters selected by the South Pole Telescope using a new publicly available forward-modelling projection code, MBPROJ2, assuming hydrostatic equilibrium. By fitting a power law plus constant entropy model we find no evidence for a central entropy floor in the lowest entropy systems. A model of the underlying central entropy distribution shows a narrow peak close to zero entropy which accounts for 60 per cent of the systems, and a second broader peak around 130 keV cm2. We look for evolution over the 0.28-1.2 redshift range of the sample in density, pressure, entropy and cooling time at 0.015R500 and at 10 kpc radius. By modelling the evolution of the central quantities with a simple model, we find no evidence for a non-zero slope with redshift. In addition, a non-parametric sliding median shows no significant change. The fraction of cool-core clusters with central cooling times below 2 Gyr is consistent above and below z = 0.6 (˜30-40 per cent). Both by comparing the median thermodynamic profiles, centrally biased towards cool cores, in two redshift bins, and by modelling the evolution of the unbiased average profile as a function of redshift, we find no significant evolution beyond self-similar scaling in any of our examined quantities. Our average modelled radial density, entropy and cooling-time profiles appear as power laws with breaks around 0.2R500. The dispersion in these quantities rises inwards of this radius to around 0.4 dex, although some of this scatter can be fitted by a bimodal model.

  1. A catalogue of masses, structural parameters and velocity dispersion profiles of 112 Milky Way globular clusters

    Science.gov (United States)

    Baumgardt, H.; Hilker, M.

    2018-05-01

    We have determined masses, stellar mass functions and structural parameters of 112 Milky Way globular clusters by fitting a large set of N-body simulations to their velocity dispersion and surface density profiles. The velocity dispersion profiles were calculated based on a combination of more than 15,000 high-precision radial velocities which we derived from archival ESO/VLT and Keck spectra together with ˜20, 000 published radial velocities from the literature. Our fits also include the stellar mass functions of the globular clusters, which are available for 47 clusters in our sample, allowing us to self-consistently take the effects of mass segregation and ongoing cluster dissolution into account. We confirm the strong correlation between the global mass functions of globular clusters and their relaxation times recently found by Sollima & Baumgardt (2017). We also find a correlation of the escape velocity from the centre of a globular cluster and the fraction of first generation stars (FG) in the cluster recently derived for 57 globular clusters by Milone et al. (2017), but no correlation between the FG star fraction and the global mass function of a globular cluster. This could indicate that the ability of a globular cluster to keep the wind ejecta from the polluting star(s) is the crucial parameter determining the presence and fraction of second generation stars and not its later dynamical mass loss.

  2. A new experimental setup for high-pressure catalytic activity measurements on surface deposited mass-selected Pt clusters

    International Nuclear Information System (INIS)

    Watanabe, Yoshihide; Isomura, Noritake

    2009-01-01

    A new experimental setup to study catalytic and electronic properties of size-selected clusters on metal oxide substrates from the viewpoint of cluster-support interaction and to formulate a method for the development of heterogeneous catalysts such as automotive exhaust catalysts has been developed. The apparatus consists of a size-selected cluster source, a photoemission spectrometer, a scanning tunneling microscope (STM), and a high-pressure reaction cell. The high-pressure reaction cell measurements provided information on catalytic properties in conditions close to practical use. The authors investigated size-selected platinum clusters deposited on a TiO 2 (110) surface using a reaction cell and STM. Catalytic activity measurements showed that the catalytic activities have a cluster-size dependency.

  3. Measurement of high-beta tokamak pressure profiles with multipoint Thomson scattering

    International Nuclear Information System (INIS)

    Levinton, F.M.

    1983-01-01

    A multipoint Thomson-scattering system has been developed to obtain pressure profiles along the major radius of Torus II, a high-beta tokamak. The profiles obtained during the 20 to 25 μs lifetime of the discharge indicates that the plasma has a peak temperature of 80 eV and density of 1.0 x 10 15 cm - 3 . The profiles remain fairly constant during this time until the equilibrium is lost, after which the temperature and density decays to 10 eV and 10 14 cm - 3 very quickly (approx. 1 μs). Experimental results show Torus II has a high-beta ( approx. 10%) equilibrium, with a strong shift of the peak of the pressure profile towards the outside. Numerical results from a 2-D free boundary MHD equilibrium code have obtained equilibria which closely approximate the experimentally measured profiles

  4. Relaxation effects in ionic mobility and cluster formation: negative ions in SF6 at high pressures

    International Nuclear Information System (INIS)

    Juarez, A M; De Urquijo, J; Hinojosa, G; Hernandez-Avila, J L; Basurto, E

    2010-01-01

    The relaxation effects of the ionic mobility and the formation of negative-ion clusters in SF 6 are studied in this work. For this purpose, we have measured the mobility of negative ions in SF 6 over the pressure range 100-800 Torr at a fixed value of density-normalized electric field, E/N, of 20 Td (1 Townsend = 10 -17 V cm 2 ). The data obtained show a clear dependence of the negative-ion drift velocity on drift distance. It is observed that the drift velocity (mobility) reaches a steady-state value only for drift distances above 2 cm, over the studied pressure range. In addition to this, we have observed that the ionic mobility depends strongly on the gas pressure. An explanation of this dependence of the ionic mobility on gas pressure is given in terms of a negative-ion clustering formation process. It was found that the assumption of a linear dependence of the cluster ion mass on pressure provides a satisfactory explanation for the observed mobilities.

  5. Variations in Decision-Making Profiles by Age and Gender: A Cluster-Analytic Approach

    Science.gov (United States)

    Delaney, Rebecca; Strough, JoNell; Parker, Andrew M.; de Bruin, Wandi Bruine

    2015-01-01

    Using cluster-analysis, we investigated whether rational, intuitive, spontaneous, dependent, and avoidant styles of decision making (Scott & Bruce, 1995) combined to form distinct decision-making profiles that differed by age and gender. Self-report survey data were collected from 1,075 members of RAND’s American Life Panel (56.2% female, 18–93 years, Mage = 53.49). Three decision-making profiles were identified: affective/experiential, independent/self-controlled, and an interpersonally-oriented dependent profile. Older people were less likely to be in the affective/experiential profile and more likely to be in the independent/self-controlled profile. Women were less likely to be in the affective/experiential profile and more likely to be in the interpersonally-oriented dependent profile. Interpersonally-oriented profiles are discussed as an overlooked but important dimension of how people make important decisions. PMID:26005238

  6. Variations in Decision-Making Profiles by Age and Gender: A Cluster-Analytic Approach.

    Science.gov (United States)

    Delaney, Rebecca; Strough, JoNell; Parker, Andrew M; de Bruin, Wandi Bruine

    2015-10-01

    Using cluster-analysis, we investigated whether rational, intuitive, spontaneous, dependent, and avoidant styles of decision making (Scott & Bruce, 1995) combined to form distinct decision-making profiles that differed by age and gender. Self-report survey data were collected from 1,075 members of RAND's American Life Panel (56.2% female, 18-93 years, M age = 53.49). Three decision-making profiles were identified: affective/experiential, independent/self-controlled, and an interpersonally-oriented dependent profile. Older people were less likely to be in the affective/experiential profile and more likely to be in the independent/self-controlled profile. Women were less likely to be in the affective/experiential profile and more likely to be in the interpersonally-oriented dependent profile. Interpersonally-oriented profiles are discussed as an overlooked but important dimension of how people make important decisions.

  7. Code Description for Generation of Meteorological Height and Pressure Level and Layer Profiles

    Science.gov (United States)

    2016-06-01

    defined by user input height or pressure levels. It can process input profiles from sensing systems such as radiosonde, lidar, or wind profiling radar...routine may be required for different input types and formats. meteorological sounding interpolation , integrated mean layer values, US Army Research...or other radiosonde soundings. There are 2 main versions or “methods” that produce output in height- or pressure-based profiles of interpolated level

  8. The role of point defect clusters in reactor pressure vessel embrittlement

    International Nuclear Information System (INIS)

    Stoller, R.E.

    1993-01-01

    Radiation-induced point defect clusters (PDC) are a plausible source of matrix hardening in reactor pressure vessel (RPV) steels in addition to copper-rich precipitates. These PDCs can be of either interstitial or vacancy type, and could exist in either 2 or 3-D shapes, e.g. small loops, voids, or stacking fault tetrahedra. Formation and evolution of PDCs are primarily determined by displacement damage rate and irradiation temperature. There is experimental evidence that size distributions of these clusters are also influenced by impurities such as copper. A theoretical model has been developed to investigate potential role of PDCs in RPV embrittlement. The model includes a detailed description of interstitial cluster population; vacancy clusters are treated in a more approximate fashion. The model has been used to examine a broad range of irradiation and material parameters. Results indicate that magnitude of hardening increment due to these clusters can be comparable to that attributed to copper precipitates. Both interstitial and vacancy type defects contribute to this hardening, with their relative importance determined by the specific irradiation conditions

  9. CONSTRAINING CLUSTER PHYSICS WITH THE SHAPE OF X-RAY CLUSTERS: COMPARISON OF LOCAL X-RAY CLUSTERS VERSUS ΛCDM CLUSTERS

    International Nuclear Information System (INIS)

    Lau, Erwin T.; Nagai, Daisuke; Kravtsov, Andrey V.; Vikhlinin, Alexey; Zentner, Andrew R.

    2012-01-01

    Recent simulations of cluster formation have demonstrated that condensation of baryons into central galaxies during cluster formation can drive the shape of the gas distribution in galaxy clusters significantly rounder out to their virial radius. These simulations generally predict stellar fractions within cluster virial radii that are ∼2-3 times larger than the stellar masses deduced from observations. In this paper, we compare ellipticity profiles of simulated clusters performed with varying input physics (radiative cooling, star formation, and supernova feedback) to the cluster ellipticity profiles derived from Chandra and ROSAT observations, in an effort to constrain the fraction of gas that cools and condenses into the central galaxies within clusters. We find that local relaxed clusters have an average ellipticity of ε = 0.18 ± 0.05 in the radial range of 0.04 ≤ r/r 500 ≤ 1. At larger radii r > 0.1r 500 , the observed ellipticity profiles agree well with the predictions of non-radiative simulations. In contrast, the ellipticity profiles of simulated clusters that include dissipative gas physics deviate significantly from the observed ellipticity profiles at all radii. The dissipative simulations overpredict (underpredict) ellipticity in the inner (outer) regions of galaxy clusters. By comparing simulations with and without dissipative gas physics, we show that gas cooling causes the gas distribution to be more oblate in the central regions, but makes the outer gas distribution more spherical. We find that late-time gas cooling and star formation are responsible for the significantly oblate gas distributions in cluster cores, but the gas shapes outside of cluster cores are set primarily by baryon dissipation at high redshift (z ≥ 2). Our results indicate that the shapes of X-ray emitting gas in galaxy clusters, especially at large radii, can be used to place constraints on cluster gas physics, making it potential probes of the history of baryonic

  10. An experimental study of burnout and pressure drop in 19-rod clusters

    International Nuclear Information System (INIS)

    Edwards, P.A.

    1976-03-01

    This report presents experimental burnout and pressure drop data obtained from three 19-rod clusters, both wire wrapped and grid supported, and with both non-uniform and uniform radial heat flux. The clusters all had uniform axial heating, a heated length of 4 feet, and 5/8 in. diameters rods, though the rod spacings were somewhat different and only 18 rods were heated in the grid supported cluster. Tests were carried out in high temperature water/steam at 1000 psi flowing vertically upwards with a mass velocity of 0.5 x 10 6 to 2.5 x 10 6 lbs/ft 2 hr. (U.K.)

  11. Numerical Investigation of Pressure Profile in Hydrodynamic Lubrication Thrust Bearing.

    Science.gov (United States)

    Najar, Farooq Ahmad; Harmain, G A

    2014-01-01

    Reynolds equation is solved using finite difference method (FDM) on the surface of the tilting pad to find the pressure distribution in the lubricant oil film. Different pressure profiles with grid independence are described. The present work evaluates pressure at various locations after performing a thorough grid refinement. In recent similar works, this aspect has not been addressed. However, present study shows that it can have significant effect on the pressure profile. Results of a sector shaped pad are presented and it is shown that the maximum average value of pressure is 12% (approximately) greater than the previous results. Grid independence occurs after 24 × 24 grids. A parameter "ψ" has been proposed to provide convenient indicator of obtaining grid independent results. ψ = |(P refinedgrid - P Refrence-grid)/P refinedgrid|, ψ ≤ ε, where "ε" can be fixed to a convenient value and a constant minimum film thickness value of 75 μm is used in present study. This important parameter is highlighted in the present work; the location of the peak pressure zone in terms of (r, θ) coordinates is getting shifted by changing the grid size which will help the designer and experimentalist to conveniently determine the position of pressure measurement probe.

  12. Numerical Investigation of Pressure Profile in Hydrodynamic Lubrication Thrust Bearing

    Science.gov (United States)

    Najar, Farooq Ahmad; Harmain, G. A.

    2014-01-01

    Reynolds equation is solved using finite difference method (FDM) on the surface of the tilting pad to find the pressure distribution in the lubricant oil film. Different pressure profiles with grid independence are described. The present work evaluates pressure at various locations after performing a thorough grid refinement. In recent similar works, this aspect has not been addressed. However, present study shows that it can have significant effect on the pressure profile. Results of a sector shaped pad are presented and it is shown that the maximum average value of pressure is 12% (approximately) greater than the previous results. Grid independence occurs after 24 × 24 grids. A parameter “ψ” has been proposed to provide convenient indicator of obtaining grid independent results. ψ = |(P refinedgrid − P Refrence-grid)/P refinedgrid|, ψ ≤ ε, where “ε” can be fixed to a convenient value and a constant minimum film thickness value of 75 μm is used in present study. This important parameter is highlighted in the present work; the location of the peak pressure zone in terms of (r, θ) coordinates is getting shifted by changing the grid size which will help the designer and experimentalist to conveniently determine the position of pressure measurement probe. PMID:27350977

  13. Transcriptome profiling of TDC cluster deletion mutant of Enterococcus faecalis V583

    Directory of Open Access Journals (Sweden)

    Marta Perez

    2016-09-01

    Full Text Available The species Enterococcus faecalis is able to catabolise the amino acid tyrosine into the biogenic amine tyramine by the tyrosine decarboxilase (TDC pathway Ladero et al. (2012 [1]. The TDC cluster comprises four genes: tyrS, an aminoacyl-tRNA synthetase-like gene; tdcA, which encodes the tyrosine decarboxylase; tyrP, a tyrosine/tyramine exchanger gene and nhaC-2, which encodes an Na+/H+ antiporter and whose role in the tyramine biosynthesis remains unknown [2]. In E. faecalis V583 the last three genes are co-transcribed as a single polycistronic mRNA forming the catabolic operon, while tyrS is transcribed independently of the catabolic genes as a monocistronic mRNA [2]. The catabolic operon is transcriptionally induced by tyrosine and acidic pH. On the opposite, the tyrS expression is repressed by tyrosine concentrations [2]. In this work we report the transcriptional profiling of the TDC cluster deletion mutant (E. faecalis V583 ΔTDC [2] compared to the wild-type strain, both grown in M17 medium supplemented with tyrosine. The transcriptional profile data of TDC cluster-regulated genes were deposited in the Gene Expression Omnibus (GEO database under accession no. GSE77864.

  14. Galaxy Clusters: Substructure and Mass Systematics

    Science.gov (United States)

    Zhang, Yu-Ying

    2010-07-01

    We calibrate the X-ray measured hydrostatic equilibrium (H.E.) mass and assess the origin of the H.E. mass systematics using 2-D spectrally measured X-ray properties. We obtained that the average X-ray mass derived from H.E. using XMM-Newton data is lower compared to the weak lensing mass from Subaru data for relaxed clusters in a sample of 12 clusters at z~0.2. This is comparable to the expectation of numerical simulations because of the non-thermal pressure support due to turbulence and bulk motions. The gas mass to weak lensing mass ratio shows no dependence on the cluster morphology, which indicates that the gas mass may be a good mass proxy regardless of the cluster dynamical state. To understand the origin of the systematics of the H.E. mass, we investigated 4 nearby clusters, for which the substructure is quantified by the radial fluctuations in the spectrally measured 2-D maps by a cumulative/differential scatter profile relative to the mean profile within/at a given radius. The amplitude of and the discontinuity in the scatter complements 2-D substructure diagnostics, e.g. indicating the most disturbed radial range. There is a tantalizing link between the substructure identified using the scatter of the entropy and pressure fluctuations and the deviation of the H.E. mass relative to the expected mass based on the representative scaling relation, e.g., M-Mgas, particularly at r500-the radius within which the over-density, Δ, is 500 with respect to the critical density. This indicates that at larger radii, the systematic error of the H.E. mass may well be caused by substructure.

  15. ON THE CLUSTER PHYSICS OF SUNYAEV-ZEL'DOVICH AND X-RAY SURVEYS. II. DECONSTRUCTING THE THERMAL SZ POWER SPECTRUM

    International Nuclear Information System (INIS)

    Battaglia, N.; Bond, J. R.; Pfrommer, C.; Sievers, J. L.

    2012-01-01

    Secondary anisotropies in the cosmic microwave background are a treasure-trove of cosmological information. Interpreting current experiments probing them are limited by theoretical uncertainties rather than by measurement errors. Here we focus on the secondary anisotropies resulting from the thermal Sunyaev-Zel'dovich (tSZ) effect; the amplitude of which depends critically on the average thermal pressure profile of galaxy groups and clusters. To this end, we use a suite of hydrodynamical TreePM-SPH simulations that include radiative cooling, star formation, supernova feedback, and energetic feedback from active galactic nuclei. We examine in detail how the pressure profile depends on cluster radius, mass, and redshift and provide an empirical fitting function. We employ three different approaches for calculating the tSZ power spectrum: an analytical approach that uses our pressure profile fit, a semianalytical method of pasting our pressure fit onto simulated clusters, and a direct numerical integration of our simulated volumes. We demonstrate that the detailed structure of the intracluster medium and cosmic web affect the tSZ power spectrum. In particular, the substructure and asphericity of clusters increase the tSZ power spectrum by 10%-20% at l ∼ 2000-8000, with most of the additional power being contributed by substructures. The contributions to the power spectrum from radii larger than R 500 is ∼20% at l = 3000, thus clusters interiors (r 500 ) dominate the power spectrum amplitude at these angular scales.

  16. ON THE CLUSTER PHYSICS OF SUNYAEV-ZEL'DOVICH AND X-RAY SURVEYS. II. DECONSTRUCTING THE THERMAL SZ POWER SPECTRUM

    Energy Technology Data Exchange (ETDEWEB)

    Battaglia, N. [Department of Astronomy and Astrophysics, University of Toronto, 50 St George, Toronto, ON M5S 3H4 (Canada); Bond, J. R.; Pfrommer, C.; Sievers, J. L. [Canadian Institute for Theoretical Astrophysics, 60 St George, Toronto, ON M5S 3H8 (Canada)

    2012-10-20

    Secondary anisotropies in the cosmic microwave background are a treasure-trove of cosmological information. Interpreting current experiments probing them are limited by theoretical uncertainties rather than by measurement errors. Here we focus on the secondary anisotropies resulting from the thermal Sunyaev-Zel'dovich (tSZ) effect; the amplitude of which depends critically on the average thermal pressure profile of galaxy groups and clusters. To this end, we use a suite of hydrodynamical TreePM-SPH simulations that include radiative cooling, star formation, supernova feedback, and energetic feedback from active galactic nuclei. We examine in detail how the pressure profile depends on cluster radius, mass, and redshift and provide an empirical fitting function. We employ three different approaches for calculating the tSZ power spectrum: an analytical approach that uses our pressure profile fit, a semianalytical method of pasting our pressure fit onto simulated clusters, and a direct numerical integration of our simulated volumes. We demonstrate that the detailed structure of the intracluster medium and cosmic web affect the tSZ power spectrum. In particular, the substructure and asphericity of clusters increase the tSZ power spectrum by 10%-20% at l {approx} 2000-8000, with most of the additional power being contributed by substructures. The contributions to the power spectrum from radii larger than R {sub 500} is {approx}20% at l = 3000, thus clusters interiors (r < R {sub 500}) dominate the power spectrum amplitude at these angular scales.

  17. Molecular depth profiling of multi-layer systems with cluster ion sources

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Juan [Department of Chemistry, Penn State University, University Park, PA 16802 (United States); Winograd, Nicholas [Department of Chemistry, Penn State University, University Park, PA 16802 (United States)]. E-mail: nxw@psu.edu

    2006-07-30

    Cluster bombardment of molecular films has created new opportunities for SIMS research. To more quantitatively examine the interaction of cluster beams with organic materials, we have developed a reproducible platform consisting of a well-defined sugar film (trehalose) doped with peptides. Molecular depth profiles have been acquired with these systems using C{sub 60} {sup +} bombardment. In this study, we utilize this platform to determine the feasibility of examining buried interfaces for multi-layer systems. Using C{sub 60} {sup +} at 20 keV, several systems have been tested including Al/trehalose/Si, Al/trehalose/Al/Si, Ag/trehalose/Si and ice/trehalose/Si. The results show that there can be interactions between the layers during the bombardment process that prevent a simple interpretation of the depth profile. We find so far that the best results are obtained when the mass of the overlayer atoms is less than or nearly equal to the mass of the atoms in buried molecules. In general, these observations suggest that C{sub 60} {sup +} bombardment can be successfully applied to interface characterization of multi-layer systems if the systems are carefully chosen.

  18. Formation mechanism of solute clusters under neutron irradiation in ferritic model alloys and in a reactor pressure vessel steel: clusters of defects

    International Nuclear Information System (INIS)

    Meslin-Chiffon, E.

    2007-11-01

    The embrittlement of reactor pressure vessel (RPV) under irradiation is partly due to the formation of point defects (PD) and solute clusters. The aim of this work was to gain more insight into the formation mechanisms of solute clusters in low copper ([Cu] = 0.1 wt%) FeCu and FeCuMnNi model alloys, in a copper free FeMnNi model alloy and in a low copper French RPV steel (16MND5). These materials were neutron-irradiated around 300 C in a test reactor. Solute clusters were characterized by tomographic atom probe whereas PD clusters were simulated with a rate theory numerical code calibrated under cascade damage conditions using transmission electron microscopy analysis. The confrontation between experiments and simulation reveals that a heterogeneous irradiation-induced solute precipitation/segregation probably occurs on PD clusters. (author)

  19. Cardiometabolic risk clustering in spinal cord injury: results of exploratory factor analysis.

    Science.gov (United States)

    Libin, Alexander; Tinsley, Emily A; Nash, Mark S; Mendez, Armando J; Burns, Patricia; Elrod, Matt; Hamm, Larry F; Groah, Suzanne L

    2013-01-01

    Evidence suggests an elevated prevalence of cardiometabolic risks among persons with spinal cord injury (SCI); however, the unique clustering of risk factors in this population has not been fully explored. The purpose of this study was to describe unique clustering of cardiometabolic risk factors differentiated by level of injury. One hundred twenty-one subjects (mean 37 ± 12 years; range, 18-73) with chronic C5 to T12 motor complete SCI were studied. Assessments included medical histories, anthropometrics and blood pressure, and fasting serum lipids, glucose, insulin, and hemoglobin A1c (HbA1c). The most common cardiometabolic risk factors were overweight/obesity, high levels of low-density lipoprotein (LDL-C), and low levels of high-density lipoprotein (HDL-C). Risk clustering was found in 76.9% of the population. Exploratory principal component factor analysis using varimax rotation revealed a 3-factor model in persons with paraplegia (65.4% variance) and a 4-factor solution in persons with tetraplegia (73.3% variance). The differences between groups were emphasized by the varied composition of the extracted factors: Lipid Profile A (total cholesterol [TC] and LDL-C), Body Mass-Hypertension Profile (body mass index [BMI], systolic blood pressure [SBP], and fasting insulin [FI]); Glycemic Profile (fasting glucose and HbA1c), and Lipid Profile B (TG and HDL-C). BMI and SBP formed a separate factor only in persons with tetraplegia. Although the majority of the population with SCI has risk clustering, the composition of the risk clusters may be dependent on level of injury, based on a factor analysis group comparison. This is clinically plausible and relevant as tetraplegics tend to be hypo- to normotensive and more sedentary, resulting in lower HDL-C and a greater propensity toward impaired carbohydrate metabolism.

  20. Pressure profiles of plasmas confined in the field of a magnetic dipole

    International Nuclear Information System (INIS)

    Davis, Matthew S; Mauel, M E; Garnier, Darren T; Kesner, Jay

    2014-01-01

    Equilibrium pressure profiles of plasmas confined in the field of a dipole magnet are reconstructed using magnetic and x-ray measurements on the levitated dipole experiment (LDX). LDX operates in two distinct modes: with the dipole mechanically supported and with the dipole magnetically levitated. When the dipole is mechanically supported, thermal particles are lost along the field to the supports, and the plasma pressure is highly peaked and consists of energetic, mirror-trapped electrons that are created by electron cyclotron resonance heating. By contrast, when the dipole is magnetically levitated losses to the supports are eliminated and particles are lost via slower cross-field transport that results in broader, but still peaked, plasma pressure profiles. (paper)

  1. A new algorithm predicts pressure and temperature profiles of gas/gas-condensate transmission pipelines

    Energy Technology Data Exchange (ETDEWEB)

    Mokhatab, Saied [OIEC - Oil Industries' Engineering and Construction Group, Tehran (Iran, Islamic Republic of); Vatani, Ali [University of Tehran (Iran, Islamic Republic of)

    2003-07-01

    The main objective of the present study has been the development of a relatively simple analytical algorithm for predicting flow temperature and pressure profiles along the two-phase, gas/gas-condensate transmission pipelines. Results demonstrate the ability of the method to predict reasonably accurate pressure gradient and temperature gradient profiles under operating conditions. (author)

  2. Measurement of the dark matter velocity anisotropy profile in galaxy clusters

    International Nuclear Information System (INIS)

    Host, Ole

    2009-01-01

    Dark matter halos contribute the major part of the mass of galaxy clusters and the formation of these cosmological structures have been investigated in numerical simulations. Observations have been found to be in good agreement with the numerical predictions regarding the spatial distribution of dark matter, i.e. the mass profile. However, the dynamics of dark matter in halos has so far proved a greater challenge to probe observationally. We have used observations of 16 relaxed galaxy clusters to show that the dark matter velocity dispersion is larger along the radial direction than along the tangential, and that the magnitude of this velocity anisotropy β varies with radius. This measurement implies that the collective behaviour of dark matter particles is fundamentally different from that of baryonic particles and constrains the self-interaction per unit mass. The radial variation of the anisotropy velocity agrees with the predictions so that, on cluster scales, there is now excellent agreement between numerical predictions and observations regarding the phase space of dark matter.

  3. Jellyfish: Observational Properties of Extreme Ram-Pressure Stripping Events in Massive Galaxy Clusters

    Science.gov (United States)

    Conor, McPartland; Ebeling, Harald; Roediger, Elke

    2015-08-01

    We investigate the physical origin and observational signatures of extreme ram-pressure stripping (RPS) in 63 massive galaxy clusters at z=0.3-0.7, based on data in the F606W passband obtained with the Advanced Camera for Surveys aboard the Hubble Space Telescope. Using a training set of a dozen ``jellyfish" galaxies identified earlier in the same imaging data, we define quantitative morphological criteria to select candidate galaxies which are similar to known cases of RPS. Considering a sample of 16 ``jellyfish" galaxies (10 of which we present for the first time), we visually derive estimates of the projected direction of motion based on dynamical features such as apparent compression shocks and debris trails. Our findings suggest that the observed events occur primarily at large distances from the cluster core and involve infall trajectories featuring high impact parameters. Simple models of cluster growth show that such trajectories are consistent with two scenarios: 1) galaxy infall along filaments; and 2) infall at high velocities (≥1000 km/s) characteristic of cluster mergers. The observed distribution of events is best described by timescales of ˜few Myr in agreement with recent numerical simulations of RPS. The broader areal coverage of the Hubble Frontier Fields should provide an even larger sample of RPS events to determine the relative contributions of infall and cluster mergers. Prompted by the discovery of several jellyfish galaxies whose brightness in the F606W passband rivals or exceeds that of the respective brightest cluster galaxy, we attempt to constrain the luminosity function of galaxies undergoing RPS. The observed significant excess at the bright end compared to the luminosity functions of blue cluster members strongly suggests enhanced star formation, thus challenging theoretical and numerical studies according to which RPS merely displaces existing star-forming regions. In-depth studies of individual objects will help test our

  4. Identifying specific profiles in patients with different degrees of painful knee osteoarthritis based on serological biochemical and mechanistic pain biomarkers: a diagnostic approach based on cluster analysis.

    Science.gov (United States)

    Egsgaard, Line Lindhardt; Eskehave, Thomas Navndrup; Bay-Jensen, Anne C; Hoeck, Hans Christian; Arendt-Nielsen, Lars

    2015-01-01

    Biochemical and pain biomarkers can be applied to patients with painful osteoarthritis profiles and may provide more details compared with conventional clinical tools. The aim of this study was to identify an optimal combination of biochemical and pain biomarkers for classification of patients with different degrees of knee pain and joint damage. Such profiling may provide new diagnostic and therapeutic options. A total of 216 patients with different degrees of knee pain (maximal pain during the last 24 hours rated on a visual analog scale [VAS]) (VAS 0-100) and 64 controls (VAS 0-9) were recruited. Patients were separated into 3 groups: VAS 10 to 39 (N = 81), VAS 40 to 69 (N = 70), and VAS 70 to 100 (N = 65). Pressure pain thresholds, temporal summation to pressure stimuli, and conditioning pain modulation were measured from the peripatellar and extrasegmental sites. Biochemical markers indicative for autoinflammation and immunity (VICM, CRP, and CRPM), synovial inflammation (CIIIM), cartilage loss (CIIM), and bone degradation (CIM) were analyzed. WOMAC, Lequesne, and pain catastrophizing scores were collected. Principal component analysis was applied to select the optimal variable subset, and cluster analysis was applied to this subset to create distinctly different knee pain profiles. Four distinct knee pain profiles were identified: profile A (N = 27), profile B (N = 59), profile C (N = 85), and profile D (N = 41). Each knee pain profile had a unique combination of biochemical markers, pain biomarkers, physical impairments, and psychological factors that may provide the basis for mechanism-based diagnosis, individualized treatment, and selection of patients for clinical trials evaluating analgesic compounds. These results introduce a new profiling for knee OA and should be regarded as preliminary.

  5. Resemblance profiles as clustering decision criteria: Estimating statistical power, error, and correspondence for a hypothesis test for multivariate structure.

    Science.gov (United States)

    Kilborn, Joshua P; Jones, David L; Peebles, Ernst B; Naar, David F

    2017-04-01

    Clustering data continues to be a highly active area of data analysis, and resemblance profiles are being incorporated into ecological methodologies as a hypothesis testing-based approach to clustering multivariate data. However, these new clustering techniques have not been rigorously tested to determine the performance variability based on the algorithm's assumptions or any underlying data structures. Here, we use simulation studies to estimate the statistical error rates for the hypothesis test for multivariate structure based on dissimilarity profiles (DISPROF). We concurrently tested a widely used algorithm that employs the unweighted pair group method with arithmetic mean (UPGMA) to estimate the proficiency of clustering with DISPROF as a decision criterion. We simulated unstructured multivariate data from different probability distributions with increasing numbers of objects and descriptors, and grouped data with increasing overlap, overdispersion for ecological data, and correlation among descriptors within groups. Using simulated data, we measured the resolution and correspondence of clustering solutions achieved by DISPROF with UPGMA against the reference grouping partitions used to simulate the structured test datasets. Our results highlight the dynamic interactions between dataset dimensionality, group overlap, and the properties of the descriptors within a group (i.e., overdispersion or correlation structure) that are relevant to resemblance profiles as a clustering criterion for multivariate data. These methods are particularly useful for multivariate ecological datasets that benefit from distance-based statistical analyses. We propose guidelines for using DISPROF as a clustering decision tool that will help future users avoid potential pitfalls during the application of methods and the interpretation of results.

  6. Pressure profiles of the BRing based on the simulation used in the CSRm

    Science.gov (United States)

    Wang, J. C.; Li, P.; Yang, J. C.; Yuan, Y. J.; Wu, B.; Chai, Z.; Luo, C.; Dong, Z. Q.; Zheng, W. H.; Zhao, H.; Ruan, S.; Wang, G.; Liu, J.; Chen, X.; Wang, K. D.; Qin, Z. M.; Yin, B.

    2017-07-01

    HIAF-BRing, a new multipurpose accelerator facility of the High Intensity heavy-ion Accelerator Facility project, requires an extremely high vacuum lower than 10-11 mbar to fulfill the requirements of radioactive beam physics and high energy density physics. To achieve the required process pressure, the bench-marked codes of VAKTRAK and Molflow+ are used to simulate the pressure profiles of the BRing system. In order to ensure the accuracy of the implementation of VAKTRAK, the computational results are verified by measured pressure data and compared with a new simulation code BOLIDE on the current synchrotron CSRm. Since the verification of VAKTRAK has been done, the pressure profiles of the BRing are calculated with different parameters such as conductance, out-gassing rates and pumping speeds. According to the computational results, the optimal parameters are selected to achieve the required pressure for the BRing.

  7. Classification of protein profiles using fuzzy clustering techniques

    DEFF Research Database (Denmark)

    Karemore, Gopal; Mullick, Jhinuk B.; Sujatha, R.

    2010-01-01

     Present  study  has  brought  out  a  comparison  of PCA  and  fuzzy  clustering  techniques  in  classifying  protein profiles  (chromatogram)  of  homogenates  of  different  tissue origins:  Ovarian,  Cervix,  Oral  cancers,  which  were  acquired using HPLC–LIF (High Performance Liquid...... Chromatography- Laser   Induced   Fluorescence)   method   developed   in   our laboratory. Study includes 11 chromatogram spectra each from oral,  cervical,  ovarian  cancers  as  well  as  healthy  volunteers. Generally  multivariate  analysis  like  PCA  demands  clear  data that   is   devoid   of   day......   PCA   mapping   in   classifying   various cancers from healthy spectra with classification rate up to 95 % from  60%.  Methods  are  validated  using  various  clustering indexes   and   shows   promising   improvement   in   developing optical pathology like HPLC-LIF for early detection of various...

  8. Active Galactic Nuclei Feedback and Clusters Biman B. Nath

    Indian Academy of Sciences (India)

    entropy into the ICM gas. The recently determined universal pressure pro- file of the ICM gas has been used and after comparing with the entropy profile of the gas from gravitational effects of the dark matter halo, the additional entropy injected by non-gravitational sources, as a function of the total cluster mass is determined.

  9. Can pyrene probes be used to measure lateral pressure profiles of lipid membranes? Perspective through atomistic simulations

    DEFF Research Database (Denmark)

    Franova, M. D.; Vattulainen, I.; Ollila, O. H. S.

    2014-01-01

    The lateral pressure profile of lipid bilayers has gained a lot of attention, since changes in the pressure profile have been suggested to shift the membrane protein conformational equilibrium. This relation has been mostly studied with theoretical methods, especially with molecular dynamics....../monomer fluorescence ratio has been assumed to represent the lateral pressure in the location of the pyrene moieties. Here, we consider the validity of this assumption through atomistic molecular dynamics simulations in a DOPC (dioleoylphosphatidylcholine) membrane, which hosts di-pyr-PC probes with different acyl...... simulations, since established methods to measure the lateral pressure profile experimentally have not been available. The only experiments that have attempted to gauge the lateral pressure profile have been done by using di-pyrenyl-phosphatidylcholine (di-pyr-PC) probes. In these experiments, the excimer...

  10. Hydrodynamical simulations of coupled and uncoupled quintessence models - II. Galaxy clusters

    Science.gov (United States)

    Carlesi, Edoardo; Knebe, Alexander; Lewis, Geraint F.; Yepes, Gustavo

    2014-04-01

    We study the z = 0 properties of clusters (and large groups) of galaxies within the context of interacting and non-interacting quintessence cosmological models, using a series of adiabatic SPH simulations. Initially, we examine the average properties of groups and clusters, quantifying their differences in ΛCold Dark Matter (ΛCDM), uncoupled Dark Energy (uDE) and coupled Dark Energy (cDE) cosmologies. In particular, we focus upon radial profiles of the gas density, temperature and pressure, and we also investigate how the standard hydrodynamic equilibrium hypothesis holds in quintessence cosmologies. While we are able to confirm previous results about the distribution of baryons, we also find that the main discrepancy (with differences up to 20 per cent) can be seen in cluster pressure profiles. We then switch attention to individual structures, mapping each halo in quintessence cosmology to its ΛCDM counterpart. We are able to identify a series of small correlations between the coupling in the dark sector and halo spin, triaxiality and virialization ratio. When looking at spin and virialization of dark matter haloes, we find a weak (5 per cent) but systematic deviation in fifth force scenarios from ΛCDM.

  11. Effect of Ramadan Fasting on Blood Pressure and Lipid Profiles

    Directory of Open Access Journals (Sweden)

    Maryam sadat Amirkalali sijavandi

    2015-09-01

    Full Text Available Introduction: Ramadan is a holy month for Muslims during which avoid from eating, drinking and sexual intercourse for about 13-17 hours. The aim of this study was surveying the effects of Islamic fasting in Ramadan on lipid profile and blood pressure.Materials and Methods: we designed this study in two phases, a week before and a week after Ramadan month. Eighty nine healthy subjects with 20-50 years old were participated in this study. Blood sampling for lipid profile measurement was done in the morning and blood pressure was measured in the afternoon with digital sphygmomanometer. Statistical analysis was performed with SPSS version 16.0 software.Results: In a week after Ramadan, body weight and body mass index (BMI decreased in both sexes, comparing with the week before Ramadan measurements (p

  12. CLUSTER LENSING PROFILES DERIVED FROM A REDSHIFT ENHANCEMENT OF MAGNIFIED BOSS-SURVEY GALAXIES

    International Nuclear Information System (INIS)

    Coupon, Jean; Umetsu, Keiichi; Broadhurst, Tom

    2013-01-01

    We report the first detection of a redshift-depth enhancement of background galaxies magnified by foreground clusters. Using 300,000 BOSS survey galaxies with accurate spectroscopic redshifts, we measure their mean redshift depth behind four large samples of optically selected clusters from the Sloan Digital Sky Survey (SDSS) surveys, totaling 5000-15,000 clusters. A clear trend of increasing mean redshift toward the cluster centers is found, averaged over each of the four cluster samples. In addition, we find similar but noisier behavior for an independent X-ray sample of 158 clusters lying in the foreground of the current BOSS sky area. By adopting the mass-richness relationships appropriate for each survey, we compare our results with theoretical predictions for each of the four SDSS cluster catalogs. The radial form of this redshift enhancement is well fitted by a richness-to-mass weighted composite Navarro-Frenk-White profile with an effective mass ranging between M 200 ∼ 1.4-1.8 × 10 14 M ☉ for the optically detected cluster samples, and M 200 ∼ 5.0 × 10 14 M ☉ for the X-ray sample. This lensing detection helps to establish the credibility of these SDSS cluster surveys, and provides a normalization for their respective mass-richness relations. In the context of the upcoming bigBOSS, Subaru Prime Focus Spectrograph, and EUCLID-NISP spectroscopic surveys, this method represents an independent means of deriving the masses of cluster samples for examining the cosmological evolution, and provides a relatively clean consistency check of weak-lensing measurements, free from the systematic limitations of shear calibration

  13. Blood Pressure Profile and Hypertension in Adolescents in Port ...

    African Journals Online (AJOL)

    This study was undertaken to determine the blood pressure profile, prevalence of hypertension in apparently healthy secondary school children in Port Harcourt and the relationship between body mass index and hypertension. Materials and Methods: A cross sectional study of 1,056 adolescents, aged 10-18 years, selected ...

  14. Atmospheric pressure and temperature profiling using near IR differential absorption lidar

    Science.gov (United States)

    Korb, C. L.; Schwemmer, G. K.; Dombrowski, M.; Weng, C. Y.

    1983-01-01

    The present investigation is concerned with differential absorption lidar techniques for remotely measuring the atmospheric temperature and pressure profile, surface pressure, and cloud top pressure-height. The procedure used in determining the pressure is based on the conduction of high-resolution measurements of absorption in the wings of lines in the oxygen A band. Absorption with respect to these areas is highly pressure sensitive in connection with the mechanism of collisional line broadening. The method of temperature measurement utilizes a determination of the absorption at the center of a selected line in the oxygen A band which originates from a quantum state with high ground state energy.

  15. Stream gradient Hotspot and Cluster Analysis (SL-HCA) for improving the longitudinal profiles metrics

    Science.gov (United States)

    Troiani, Francesco; Piacentini, Daniela; Seta Marta, Della

    2016-04-01

    Many researches successfully focused on stream longitudinal profiles analysis through Stream Length-gradient (SL) index for detecting, at different spatial scales, either tectonic structures or hillslope processes. The analysis and interpretation of spatial variability of SL values, both at a regional and local scale, is often complicated due to the concomitance of different factors generating SL anomalies, including the bedrock composition. The creation of lithologically-filtered SL maps is often problematic in areas where homogeneously surveyed geological maps, with a sufficient resolution are unavailable. Moreover, both the SL map classification and the unbiased anomaly detection are rather difficult. For instance, which is the best threshold to define the anomalous SL values? Further, is there a minimum along-channel extent of anomalous SL values for objectively defining over-steeped segments on long-profiles? This research investigates the relevance and potential of a new approach based on Hotspot and Cluster Analysis of SL values (SL-HCA) for detecting knickzones on long-profiles at a regional scale and for fine-tuning the interpretation of their geological-geomorphological meaning. We developed this procedure within a 2800 km2-wide area located in the mountainous sector of the Northern Apennines of Italy. The Getis-Ord Gi∗ statistic is applied for the SL-HCA approach. The value of SL, calculated starting from a 5x5 m Digital Elevation Model, is used as weighting factor and the Gi∗ index is calculated for each 50 m-long channel segment for the whole fluvial system. The outcomes indicate that high positive Gi∗ values imply the clustering of SL anomalies, thus the occurrence of knickzones on the stream long-profiles. Results show that high and very high Gi* values (i.e. values beyond two standard deviations from the mean) correlate well with the principal knickzones detected with existent lithologically-filtered SL maps. Field checks and remote sensing

  16. Pressure profiles of the BRing based on the simulation used in the CSRm

    Energy Technology Data Exchange (ETDEWEB)

    Wang, J.C., E-mail: wangjiachen@impcas.ac.cn [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Li, P., E-mail: lipeng@impcas.ac.cn [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Yang, J.C.; Yuan, Y.J. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Wu, B. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Chai, Z.; Luo, C. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Dong, Z.Q. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Zheng, W.H. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Zhao, H.; Ruan, S.; Wang, G.; Liu, J.; Chen, X.; Wang, K.D.; Qin, Z.M. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Yin, B. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China)

    2017-07-11

    HIAF-BRing, a new multipurpose accelerator facility of the High Intensity heavy-ion Accelerator Facility project, requires an extremely high vacuum lower than 10{sup −11} mbar to fulfill the requirements of radioactive beam physics and high energy density physics. To achieve the required process pressure, the bench-marked codes of VAKTRAK and Molflow+ are used to simulate the pressure profiles of the BRing system. In order to ensure the accuracy of the implementation of VAKTRAK, the computational results are verified by measured pressure data and compared with a new simulation code BOLIDE on the current synchrotron CSRm. Since the verification of VAKTRAK has been done, the pressure profiles of the BRing are calculated with different parameters such as conductance, out-gassing rates and pumping speeds. According to the computational results, the optimal parameters are selected to achieve the required pressure for the BRing.

  17. Microstructure, microbial profile and quality characteristics of high-pressure-treated chicken nuggets.

    Science.gov (United States)

    Devatkal, Suresh; Anurag, Rahul; Jaganath, Bindu; Rao, Srinivasa

    2015-10-01

    High-pressure processing (300 MPa for 5 min) as a non-thermal post-processing intervention was employed to improve the shelf life and qualities of cooked refrigerated chicken nuggets. Pomegranate peel extract (1%) was also used as a source of natural antioxidant and antimicrobial in chicken nuggets. Microstructure, microbial profile, instrumental colour, texture profile and lipid oxidation were evaluated. High-pressure treatment and pomegranate peel extract did not influence significantly the colour and textural properties of cooked chicken nuggets. Thiobarbituric acid reactive substance values significantly (p chicken nuggets were the major spoilage bacteria. © The Author(s) 2014.

  18. Real-time control of current and pressure profiles in tokamak plasmas

    International Nuclear Information System (INIS)

    Laborde, L.

    2005-12-01

    Recent progress in the field of 'advanced tokamak scenarios' prefigure the operation regime of a future thermonuclear fusion power plant. Compared to the reference regime, these scenarios offer a longer plasma confinement time thanks to increased magnetohydrodynamic stability and to a better particle and energy confinement through a reduction of plasma turbulence. This should give access to comparable fusion performances at reduced plasma current and could lead to a steady state fusion reactor since the plasma current could be entirely generated non-inductively. Access to this kind of regime is provided by the existence of an internal transport barrier, linked to the current profile evolution in the plasma, which leads to steep temperature and pressure profiles. The comparison between heat transport simulations and experiments allowed the nature of the barriers to be better understood as a region of strongly reduced turbulence. Thus, the control of this barrier in a stationary manner would be a remarkable progress, in particular in view of the experimental reactor ITER. The Tore Supra and JET tokamaks, based in France and in the United Kingdom, constitute ideal instruments for such experiments: the first one allows stationary plasmas to be maintained during several minutes whereas the second one provides unique fusion performances. In Tore Supra, real-time control experiments have been accomplished where the current profile width and the pressure profile gradient were controlled in a stationary manner using heating and current drive systems as actuators. In the JET tokamak, the determination of an empirical static model of the plasma allowed the current and pressure profiles to be simultaneously controlled and so an internal transport barrier to be sustained. Finally, the identification of a dynamic model of the plasma led to the definition of a new controller capable, in principle, of a more efficient control. (author)

  19. The diverse density profiles of galaxy clusters with self-interacting dark matter plus baryons

    Science.gov (United States)

    Robertson, Andrew; Massey, Richard; Eke, Vincent; Tulin, Sean; Yu, Hai-Bo; Bahé, Yannick; Barnes, David J.; Bower, Richard G.; Crain, Robert A.; Dalla Vecchia, Claudio; Kay, Scott T.; Schaller, Matthieu; Schaye, Joop

    2018-05-01

    We present the first simulated galaxy clusters (M200 > 1014 M⊙) with both self-interacting dark matter (SIDM) and baryonic physics. They exhibit a greater diversity in both dark matter and stellar density profiles than their counterparts in simulations with collisionless dark matter (CDM), which is generated by the complex interplay between dark matter self-interactions and baryonic physics. Despite variations in formation history, we demonstrate that analytical Jeans modelling predicts the SIDM density profiles remarkably well, and the diverse properties of the haloes can be understood in terms of their different final baryon distributions.

  20. Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles

    Directory of Open Access Journals (Sweden)

    Lee Yun-Shien

    2008-03-01

    Full Text Available Abstract Background The hierarchical clustering tree (HCT with a dendrogram 1 and the singular value decomposition (SVD with a dimension-reduced representative map 2 are popular methods for two-way sorting the gene-by-array matrix map employed in gene expression profiling. While HCT dendrograms tend to optimize local coherent clustering patterns, SVD leading eigenvectors usually identify better global grouping and transitional structures. Results This study proposes a flipping mechanism for a conventional agglomerative HCT using a rank-two ellipse (R2E, an improved SVD algorithm for sorting purpose seriation by Chen 3 as an external reference. While HCTs always produce permutations with good local behaviour, the rank-two ellipse seriation gives the best global grouping patterns and smooth transitional trends. The resulting algorithm automatically integrates the desirable properties of each method so that users have access to a clustering and visualization environment for gene expression profiles that preserves coherent local clusters and identifies global grouping trends. Conclusion We demonstrate, through four examples, that the proposed method not only possesses better numerical and statistical properties, it also provides more meaningful biomedical insights than other sorting algorithms. We suggest that sorted proximity matrices for genes and arrays, in addition to the gene-by-array expression matrix, can greatly aid in the search for comprehensive understanding of gene expression structures. Software for the proposed methods can be obtained at http://gap.stat.sinica.edu.tw/Software/GAP.

  1. Fish oil affects blood pressure and the plasma lipid profile in healthy Danish infants

    DEFF Research Database (Denmark)

    Damsgaard, C.T.; Schack-Nielsen, L.; Michaelsen, K.F.

    2006-01-01

    with an oscillometric device, and blood was sampled for analysis of erythrocyte fatty acid composition and the plasma lipid profile. This paper examines the effects of the fish oil supplement, with adjustment for the effects of the milk intervention when relevant. The fish oil intervention increased erythrocyte (n-3......Animal and epidemiologic studies indicate that early nutrition has lasting effects on metabolism and cardiovascular disease risk. In adults, (n-3) long-chain PUFA (LCPUFA) from fish oils improve blood pressure, the lipid profile, and possibly cardiovascular disease mortality. This randomized trial...... is the first to investigate the effects of fish oil on blood pressure and the lipid profile in infancy. Healthy term 9-mo old infants In 83) were randomly assigned to 5 mL fish oil daily or no fish oil for 3 mo and to 2 different milk types. Before and after the intervention, blood pressure was measured...

  2. Cluster Analysis of an International Pressure Pain Threshold Database Identifies 4 Meaningful Subgroups of Adults With Mechanical Neck Pain

    DEFF Research Database (Denmark)

    Walton, David M; Kwok, Timothy S H; Mehta, Swati

    2017-01-01

    OBJECTIVE: To determine pressure pain detection threshold (PPDT) related phenotypes of individuals with mechanical neck pain that may be identifiable in clinical practice. METHODS: This report describes a secondary analysis of 5 independent, international mechanical neck pain databases of PPDT...... values taken at both a local and distal region (total N=1176). Minor systematic differences in mean PPDT values across cohorts necessitated z-transformation before analysis, and each cohort was split into male and female sexes. Latent profile analysis (LPA) using the k-means approach was undertaken...... to identify the most parsimonious set of PPDT-based phenotypes that were both statistically and clinically meaningful. RESULTS: LPA revealed 4 distinct clusters named according to PPDT levels at the local and distal zones: low-low PPDT (67%), mod-mod (25%), mod-high (4%), and high-high (4%). Secondary...

  3. Process evaluation of a cluster-randomised trial testing a pressure ulcer prevention care bundle: a mixed-methods study.

    Science.gov (United States)

    Roberts, Shelley; McInnes, Elizabeth; Bucknall, Tracey; Wallis, Marianne; Banks, Merrilyn; Chaboyer, Wendy

    2017-02-13

    As pressure ulcers contribute to significant patient burden and increased health care costs, their prevention is a clinical priority. Our team developed and tested a complex intervention, a pressure ulcer prevention care bundle promoting patient participation in care, in a cluster-randomised trial. The UK Medical Research Council recommends process evaluation of complex interventions to provide insight into why they work or fail and how they might be improved. This study aimed to evaluate processes underpinning implementation of the intervention and explore end-users' perceptions of it, in order to give a deeper understanding of its effects. A pre-specified, mixed-methods process evaluation was conducted as an adjunct to the main trial, guided by a framework for process evaluation of cluster-randomised trials. Data was collected across eight Australian hospitals but mainly focused on the four intervention hospitals. Quantitative and qualitative data were collected across the evaluation domains: recruitment, reach, intervention delivery and response to intervention, at both cluster and individual patient level. Quantitative data were analysed using descriptive and inferential statistics. Qualitative data were analysed using thematic analysis. In the context of the main trial, which found a 42% reduction in risk of pressure ulcer with the intervention that was not significant after adjusting for clustering and covariates, this process evaluation provides important insights. Recruitment and reach among clusters and individuals was high, indicating that patients, nurses and hospitals are willing to engage with a pressure ulcer prevention care bundle. Of 799 intervention patients in the trial, 96.7% received the intervention, which took under 10 min to deliver. Patients and nurses accepted the care bundle, recognising benefits to it and describing how it enabled participation in pressure ulcer prevention (PUP) care. This process evaluation found no major failures

  4. CLASH: PRECISE NEW CONSTRAINTS ON THE MASS PROFILE OF THE GALAXY CLUSTER A2261

    International Nuclear Information System (INIS)

    Coe, Dan; Postman, Marc; Bradley, Larry; Koekemoer, Anton; Umetsu, Keiichi; Zitrin, Adi; Donahue, Megan; Medezinski, Elinor; Zheng Wei; Lemze, Doron; Carrasco, Mauricio; Anguita, Timo; Infante, Leopoldo; Geller, Margaret J.; Rines, Kenneth J.; Kurtz, Michael J.; Diaferio, Antonaldo; Nonino, Mario; Molino, Alberto; Mahdavi, Andisheh

    2012-01-01

    We precisely constrain the inner mass profile of A2261 (z = 0.225) for the first time and determine that this cluster is not 'overconcentrated' as found previously, implying a formation time in agreement with ΛCDM expectations. These results are based on multiple strong-lensing analyses of new 16-band Hubble Space Telescope imaging obtained as part of the Cluster Lensing and Supernova survey with Hubble. Combining this with revised weak-lensing analyses of Subaru wide-field imaging with five-band Subaru + KPNO photometry, we place tight new constraints on the halo virial mass M vir = (2.2 ± 0.2) × 10 15 M ☉ h –1 70 (within r vir ≈ 3 Mpc h –1 70 ) and concentration c vir = 6.2 ± 0.3 when assuming a spherical halo. This agrees broadly with average c(M, z) predictions from recent ΛCDM simulations, which span 5 ∼ 2500 ∼ 600 kpc. Agreement can be achieved by a halo elongated with a ∼2:1 axis ratio along our LOS. For this elongated halo model, we find M vir = (1.7 ± 0.2) × 10 15 M ☉ h –1 70 and c vir = 4.6 ± 0.2, placing rough lower limits on these values. The need for halo elongation can be partially obviated by non-thermal pressure support and, perhaps entirely, by systematic errors in the X-ray mass measurements. We estimate the effect of background structures based on MMT/Hectospec spectroscopic redshifts and find that these tend to lower M vir further by ∼7% and increase c vir by ∼5%.

  5. Monitoring pressure profiles across an airfoil with a fiber Bragg grating sensor array

    Science.gov (United States)

    Papageorgiou, Anthony W.; Parkinson, Luke A.; Karas, Andrew R.; Hansen, Kristy L.; Arkwright, John W.

    2018-02-01

    Fluid flow over an airfoil section creates a pressure difference across the upper and lower surfaces, thus generating lift. Successful wing design is a combination of engineering design and experience in the field, with subtleties in design and manufacture having significant impact on the amount of lift produced. Current methods of airfoil optimization and validation typically involve computational fluid dynamics (CFD) and extensive wind tunnel testing with pressure sensors embedded into the airfoil to measure the pressure over the wing. Monitoring pressure along an airfoil in a wind tunnel is typically achieved using surface pressure taps that consist of hollow tubes running from the surface of the airfoil to individual pressure sensors external to the tunnel. These pressure taps are complex to configure and not ideal for in-flight testing. Fiber Bragg grating (FBG) pressure sensing arrays provide a highly viable option for both wind tunnel and inflight pressure measurement. We present a fiber optic sensor array that can detect positive and negative pressure suitable for validating CFD models of airfoil profile sections. The sensing array presented here consists of 6 independent sensing elements, each capable of a pressure resolution of less than 10 Pa over the range of 70 kPa to 120 kPa. The device has been tested with the sensor array attached to a 90mm chord length airfoil section subjected to low velocity flow. Results show that the arrays are capable of accurately detecting variations of the pressure profile along the airfoil as the angle of attack is varied from zero to the point at which stall occurs.

  6. Association of sleep duration with arterial blood pressure profile of Gujarati Indian adolescents

    Directory of Open Access Journals (Sweden)

    Shaikh Wasim

    2010-01-01

    Full Text Available Background and Aim: Recently, National Health and Nutritional Examination Survey-1 data analysis found short sleep duration as a risk factor for hypertension in the U.S. population. However, since ethnic differences exist in the aetiopathogenesis of diseases, the current study was undertaken to study the effect of sleep duration on the blood pressure profile of Gujarati Indian adolescents. Materials and Methods: A cross-sectional study was conducted on 489 Gujarati Indian adolescents of age group 16-19 years studying in school and colleges in the local population. The participants were assessed for their sleep duration, physical activity status, body composition, blood pressure profile and cardiovascular reactivity. The sleep duration was reported by the subjects as the number of hours they slept on most of the nights in a week over the last one year. The observations of the study were then analyzed after grouping them into: 1 Adequate Sleep Duration at Night, ASDN (≥ 7 hrs and 2 Inadequate Sleep Duration at Night, ISDN (< 7 hrs groups. Student′s unpaired t-test was used to study if any significant difference (P< 0.05 existed between the groups. Results: No significant difference was found in Systolic blood pressure, Diastolic blood pressure, Pulse pressure and Mean arterial pressure between the ASDN group and the ISDN group. Physical activity status also did not differ between the two groups. However, adolescents of ISDN group showed a significantly higher level of adiposity and cardiovascular reactivity as compared to adolescents of ASDN group. Conclusion: Although short sleep duration is associated with a higher level of adiposity and cardiovascular reactivity in Gujarati Indian adolescents, it does not affect the resting blood pressure profile of these adolescents. However, longitudinal studies would be required to observe if the changes in adiposity and cardiovascular reactivity affect these adolescents in later life.

  7. Pain sensitivity profiles in patients with advanced knee osteoarthritis

    Science.gov (United States)

    Frey-Law, Laura A.; Bohr, Nicole L.; Sluka, Kathleen A.; Herr, Keela; Clark, Charles R.; Noiseux, Nicolas O.; Callaghan, John J; Zimmerman, M Bridget; Rakel, Barbara A.

    2016-01-01

    The development of patient profiles to subgroup individuals on a variety of variables has gained attention as a potential means to better inform clinical decision-making. Patterns of pain sensitivity response specific to quantitative sensory testing (QST) modality have been demonstrated in healthy subjects. It has not been determined if these patterns persist in a knee osteoarthritis population. In a sample of 218 participants, 19 QST measures along with pain, psychological factors, self-reported function, and quality of life were assessed prior to total knee arthroplasty. Component analysis was used to identify commonalities across the 19 QST assessments to produce standardized pain sensitivity factors. Cluster analysis then grouped individuals that exhibited similar patterns of standardized pain sensitivity component scores. The QST resulted in four pain sensitivity components: heat, punctate, temporal summation, and pressure. Cluster analysis resulted in five pain sensitivity profiles: a “low pressure pain” group, an “average pain” group, and three “high pain” sensitivity groups who were sensitive to different modalities (punctate, heat, and temporal summation). Pain and function differed between pain sensitivity profiles, along with sex distribution; however no differences in OA grade, medication use, or psychological traits were found. Residualizing QST data by age and sex resulted in similar components and pain sensitivity profiles. Further, these profiles are surprisingly similar to those reported in healthy populations suggesting that individual differences in pain sensitivity are a robust finding even in an older population with significant disease. PMID:27152688

  8. Cluster subgroups based on overall pressure pain sensitivity and psychosocial factors in chronic musculoskeletal pain: Differences in clinical outcomes.

    Science.gov (United States)

    Almeida, Suzana C; George, Steven Z; Leite, Raquel D V; Oliveira, Anamaria S; Chaves, Thais C

    2018-05-17

    We aimed to empirically derive psychosocial and pain sensitivity subgroups using cluster analysis within a sample of individuals with chronic musculoskeletal pain (CMP) and to investigate derived subgroups for differences in pain and disability outcomes. Eighty female participants with CMP answered psychosocial and disability scales and were assessed for pressure pain sensitivity. A cluster analysis was used to derive subgroups, and analysis of variance (ANOVA) was used to investigate differences between subgroups. Psychosocial factors (kinesiophobia, pain catastrophizing, anxiety, and depression) and overall pressure pain threshold (PPT) were entered into the cluster analysis. Three subgroups were empirically derived: cluster 1 (high pain sensitivity and high psychosocial distress; n = 12) characterized by low overall PPT and high psychosocial scores; cluster 2 (high pain sensitivity and intermediate psychosocial distress; n = 39) characterized by low overall PPT and intermediate psychosocial scores; and cluster 3 (low pain sensitivity and low psychosocial distress; n = 29) characterized by high overall PPT and low psychosocial scores compared to the other subgroups. Cluster 1 showed higher values for mean pain intensity (F (2,77)  = 10.58, p cluster 3, and cluster 1 showed higher values for disability (F (2,77)  = 3.81, p = 0.03) compared with both clusters 2 and 3. Only cluster 1 was distinct from cluster 3 according to both pain and disability outcomes. Pain catastrophizing, depression, and anxiety were the psychosocial variables that best differentiated the subgroups. Overall, these results call attention to the importance of considering pain sensitivity and psychosocial variables to obtain a more comprehensive characterization of CMP patients' subtypes.

  9. Formation of a Boundary-Free Dust Cluster in a Low-Pressure Gas-Discharge Plasma

    International Nuclear Information System (INIS)

    Usachev, A. D.; Zobnin, A. V.; Petrov, O. F.; Fortov, V. E.; Annaratone, B. M.; Thoma, M. H.; Hoefner, H.; Kretschmer, M.; Fink, M.; Morfill, G. E.

    2009-01-01

    An attraction between negatively charged micron-sized plastic particles was observed in the bulk of a low-pressure gas-discharge plasma under microgravity conditions. This attraction had led to the formation of a boundary-free dust cluster, containing one big central particle with a radius of about 6 μm and about 30 1 μm-sized particles situated on a sphere with a radius of 190 μm and with the big particle in the center. The stability of this boundary-free dust cluster was possible due to its confinement by the plasma flux on the central dust particle

  10. THE ACS FORNAX CLUSTER SURVEY. IV. DEPROJECTION OF THE SURFACE BRIGHTNESS PROFILES OF EARLY-TYPE GALAXIES IN THE VIRGO AND FORNAX CLUSTERS: INVESTIGATING THE 'CORE/POWER-LAW DICHOTOMY'

    International Nuclear Information System (INIS)

    Glass, Lisa; Ferrarese, Laura; Cote, Patrick; Blakeslee, John P.; Chen, Chin-Wei; Jordan, Andres; Infante, Leopoldo; Peng, Eric; Mei, Simona; Tonry, John L.; West, Michael J.

    2011-01-01

    Although early observations with the Hubble Space Telescope (HST) pointed to a sharp dichotomy among early-type galaxies in terms of the logarithmic slope γ' of their central surface brightness profiles, several studies in the past few years have called this finding into question. In particular, recent imaging surveys of 143 early-type galaxies belonging to the Virgo and Fornax Clusters using the Advanced Camera for Surveys (ACS) on board HST have not found a dichotomy in γ', but instead a systematic progression from central luminosity deficit to excess relative to the inward extrapolation of the best-fitting global Sersic model. Given that earlier studies also found that the dichotomy persisted when analyzing the deprojected density profile slopes, we investigate the distribution of the three-dimensional luminosity density profiles of the ACS Virgo and Fornax Cluster Survey galaxies. Having fitted the surface brightness profiles with modified Sersic models, we then deproject the galaxies using an Abel integral and measure the inner slopes γ 3D of the resulting luminosity density profiles at various fractions of the effective radius R e . We find no evidence of a dichotomy, but rather, a continuous variation in the central luminosity profiles as a function of galaxy magnitude. We introduce a parameter, Δ 3D , that measures the central deviation of the deprojected luminosity profiles from the global Sersic fit, showing that this parameter varies smoothly and systematically along the luminosity function.

  11. Pressure and cooling rate effect on polyhedron clusters in Cu-Al alloy by using molecular dynamics simulation

    Science.gov (United States)

    Celik, Fatih Ahmet

    2014-10-01

    In this study, the microstructural evolution of crystal-type and icosahedral (icos)-type polyhedrons in Cu-50 at%Al alloy based on the embedded atom method (EAM) model is studied at two cooling rates under normal and high pressures by using the molecular dynamics (MD) simulation method. The cluster-type index method (CTIM) which describes icos and defective icos polyhedrons and the new cluster-type index method (CTIM-2) which describes crystal-type polyhedrons have been used to perform polyhedron analysis in the model alloy system. The results of our simulations demonstrate that the effects of the cooling rate and pressure play an important role in the numbers of polyhedrons and their structures in the system.

  12. Pressure and cooling rate effect on polyhedron clusters in Cu–Al alloy by using molecular dynamics simulation

    Energy Technology Data Exchange (ETDEWEB)

    Celik, Fatih Ahmet, E-mail: facelik@beu.edu.tr

    2014-10-01

    In this study, the microstructural evolution of crystal-type and icosahedral (icos)-type polyhedrons in Cu–50 at%Al alloy based on the embedded atom method (EAM) model is studied at two cooling rates under normal and high pressures by using the molecular dynamics (MD) simulation method. The cluster-type index method (CTIM) which describes icos and defective icos polyhedrons and the new cluster-type index method (CTIM-2) which describes crystal-type polyhedrons have been used to perform polyhedron analysis in the model alloy system. The results of our simulations demonstrate that the effects of the cooling rate and pressure play an important role in the numbers of polyhedrons and their structures in the system.

  13. Experimental Studies of Low-Pressure Turbine Flows and Flow Control. Streamwise Pressure Profiles and Velocity Profiles

    Science.gov (United States)

    Volino, Ralph

    2012-01-01

    faculties. The geometry corresponded to "Pak B" LPT airfoil. The test section simulated LPT flow in a passage. Three experimental studies were performed: (a) Boundary layer measurements for ten baseline cases under high and low freestream turbulence conditions at five Reynolds numbers of 25,000, 50,000, 100,000, 200,000, and 300,000, based on passage exit velocity and suction surface wetted length; (b) Passive flow control studies with three thicknesses of two-dimensional bars, and two heights of three-dimensional circular cylinders with different spanwise separations, at same flow conditions as the 10 baseline cases; (c) Active flow control with oscillating synthetic (zero net mass flow) vortex generator jets, for one case with low freestream turbulence and a low Reynolds number of 25,000. The Passive flow control was successful at controlling the separation problem at low Reynolds numbers, with varying degrees of success from case to case and varying levels of impact at higher Reynolds numbers. The active flow control successfully eliminated the large separation problem for the low Reynolds number case. Very detailed data was acquired using hot-wire anemometry, including single and two velocity components, integral boundary layer quantities, turbulence statistics and spectra, turbulent shear stresses and their spectra, and intermittency, documenting transition, separation and reattachment. Models were constructed to correlate the results. The report includes a summary of the work performed and reprints of the publications describing the various studies. The folders in this supplement contain processed data in ASCII format. Streamwise pressure profiles and velocity profiles are included. The velocity profiles were acquired using single sensor and cross sensor hot-wire probes which were traversed from the wall to the freestream at various streamwise locations. In some of the flow control cases (3D Trips and Jets) profiles were acquired at multiple spanwise locations.

  14. Warming rays in cluster cool cores

    Science.gov (United States)

    Colafrancesco, S.; Marchegiani, P.

    2008-06-01

    Context: Cosmic rays are confined in the atmospheres of galaxy clusters and, therefore, they can play a crucial role in the heating of their cool cores. Aims: We discuss here the thermal and non-thermal features of a model of cosmic ray heating of cluster cores that can provide a solution to the cooling-flow problems. To this aim, we generalize a model originally proposed by Colafrancesco, Dar & DeRujula (2004) and we show that our model predicts specific correlations between the thermal and non-thermal properties of galaxy clusters and enables various observational tests. Methods: The model reproduces the observed temperature distribution in clusters by using an energy balance condition in which the X-ray energy emitted by clusters is supplied, in a quasi-steady state, by the hadronic cosmic rays, which act as “warming rays” (WRs). The temperature profile of the intracluster (IC) gas is strictly correlated with the pressure distribution of the WRs and, consequently, with the non-thermal emission (radio, hard X-ray and gamma-ray) induced by the interaction of the WRs with the IC gas and the IC magnetic field. Results: The temperature distribution of the IC gas in both cool-core and non cool-core clusters is successfully predicted from the measured IC plasma density distribution. Under this contraint, the WR model is also able to reproduce the thermal and non-thermal pressure distribution in clusters, as well as their radial entropy distribution, as shown by the analysis of three clusters studied in detail: Perseus, A2199 and Hydra. The WR model provides other observable features of galaxy clusters: a correlation of the pressure ratio (WRs to thermal IC gas) with the inner cluster temperature (P_WR/P_th) ˜ (kT_inner)-2/3, a correlation of the gamma-ray luminosity with the inner cluster temperature Lγ ˜ (kT_inner)4/3, a substantial number of cool-core clusters observable with the GLAST-LAT experiment, a surface brightness of radio halos in cool-core clusters

  15. The impact of mobile point defect clusters in a kinetic model of pressure vessel embrittlement

    International Nuclear Information System (INIS)

    Stoller, R.E.

    1998-05-01

    The results of recent molecular dynamics simulations of displacement cascades in iron indicate that small interstitial clusters may have a very low activation energy for migration, and that their migration is 1-dimensional, rather than 3-dimensional. The mobility of these clusters can have a significant impact on the predictions of radiation damage models, particularly at the relatively low temperatures typical of commercial, light water reactor pressure vessels (RPV) and other out-of-core components. A previously-developed kinetic model used to investigate RPV embrittlement has been modified to permit an evaluation of the mobile interstitial clusters. Sink strengths appropriate to both 1- and 3-dimensional motion of the clusters were evaluated. High cluster mobility leads to a reduction in the amount of predicted embrittlement due to interstitial clusters since they are lost to sinks rather than building up in the microstructure. The sensitivity of the predictions to displacement rate also increases. The magnitude of this effect is somewhat reduced if the migration is 1-dimensional since the corresponding sink strengths are lower than those for 3-dimensional diffusion. The cluster mobility can also affect the evolution of copper-rich precipitates in the model since the radiation-enhanced diffusion coefficient increases due to the lower interstitial cluster sink strength. The overall impact of the modifications to the model is discussed in terms of the major irradiation variables and material parameter uncertainties

  16. The cost-effectiveness of a patient centred pressure ulcer prevention care bundle: Findings from the INTACT cluster randomised trial.

    OpenAIRE

    Whitty, Jennifer A; McInnes, Elizabeth; Bucknall, Tracey; Webster, Joan; Gillespie, Brigid M; Banks, Merrilyn; Thalib, Lukman; Wallis, Marianne; Cumsille, Jose; Roberts, Shelley; Chaboyer, Wendy

    2017-01-01

    Pressure ulcers are serious, avoidable, costly and common adverse outcomes of healthcare. To evaluate the cost-effectiveness of a patient-centred pressure ulcer prevention care bundle compared to standard care. Cost-effectiveness and cost-benefit analyses of pressure ulcer prevention performed from the health system perspective using data collected alongside a cluster-randomised trial. Eight tertiary hospitals in Australia. Adult patients receiving either a patient-centred pressure ulcer prev...

  17. Sexual victimization and family violence among urban African American adolescent women: do violence cluster profiles predict partner violence victimization and sex trade exposure?

    Science.gov (United States)

    Kennedy, Angie C; Bybee, Deborah; Kulkarni, Shanti J; Archer, Gretchen

    2012-11-01

    Guided by an intersectional feminist perspective, we examined sexual victimization, witnessing intimate partner violence (IPV) in the family, and familial physical abuse among a sample of 180 urban African American adolescent women. We used cluster analysis to better understand the profiles of cumulative victimization, and the relationships between profiles and IPV victimization and personal exposure to the sex trade. Just under one third of the sample reported sexual victimization, with cooccurrence with both forms of family violence common. The cluster profile with high levels of severe family violence was associated with the highest rate of IPV victimization and sex trade exposure.

  18. Profiling nurses' job satisfaction, acculturation, work environment, stress, cultural values and coping abilities: A cluster analysis.

    Science.gov (United States)

    Goh, Yong-Shian; Lee, Alice; Chan, Sally Wai-Chi; Chan, Moon Fai

    2015-08-01

    This study aimed to determine whether definable profiles existed in a cohort of nursing staff with regard to demographic characteristics, job satisfaction, acculturation, work environment, stress, cultural values and coping abilities. A survey was conducted in one hospital in Singapore from June to July 2012, and 814 full-time staff nurses completed a self-report questionnaire (89% response rate). Demographic characteristics, job satisfaction, acculturation, work environment, perceived stress, cultural values, ways of coping and intention to leave current workplace were assessed as outcomes. The two-step cluster analysis revealed three clusters. Nurses in cluster 1 (n = 222) had lower acculturation scores than nurses in cluster 3. Cluster 2 (n = 362) was a group of younger nurses who reported higher intention to leave (22.4%), stress level and job dissatisfaction than the other two clusters. Nurses in cluster 3 (n = 230) were mostly Singaporean and reported the lowest intention to leave (13.0%). Resources should be allocated to specifically address the needs of younger nurses and hopefully retain them in the profession. Management should focus their retention strategies on junior nurses and provide a work environment that helps to strengthen their intention to remain in nursing by increasing their job satisfaction. © 2014 Wiley Publishing Asia Pty Ltd.

  19. Simulation of temperature-pressure profiles and wax deposition in gas-lift wells

    Directory of Open Access Journals (Sweden)

    Sevic Snezana

    2017-01-01

    Full Text Available Gas-lift is an artificial lift method in which gas is injected down the tubing- -casing annulus and enters the production tubing through the gas-lift valves to reduce the hydrostatic pressure of the formation fluid column. The gas changes pressure, temperature and fluid composition profiles throughout the production tubing string. Temperature and pressure drop along with the fluid composition changes throughout the tubing string can lead to wax, asphaltenes and inorganic salts deposition, increased emulsion stability and hydrate formation. This paper presents a new model that can sucesfully simulate temperature and pressure profiles and fluid composition changes in oil well that operates by means of gas-lift. This new model includes a pipe-in-pipe segment (production tubing inside production casing, countercurrent flow of gas-lift gas and producing fluid, heat exchange between gas-lift gas and the surrounding ambient – ground; and gas-lift gas with the fluid in the tubing. The model enables a better understanding of the multiphase fluid flow up the production tubing. Model was used to get insight into severity and locations of wax deposition. The obtained information on wax deposition can be used to plan the frequency and depth of wax removing operations. Model was developed using Aspen HYSYS software.

  20. Effects of pressure profile and plasma shaping on the n=1 internal kink mode in JT-60/JT-60U pellet fuelled plasmas

    International Nuclear Information System (INIS)

    Ozeki, Takahisa; Azumi, Masafumi

    1990-10-01

    The stability of the n=1 internal kink mode in a tokamak is numerically analyzed for plasmas with a centrally peaked pressure profile. These studies are carried out with the strongly peaked pressure inside the q=1 surface, which is based on the experimentally observed plasmas by means of injections of hydrogen-ice pellets in JT-60 tokamak. The effects of peaked pressure and shaping, i.e., elongation and triangularity, are also studied for JT-60U tokamak. The plasma with the strongly peaked pressure profile has higher critical value of poloidal beta defined within the q=1 surface than that with a parabolic pressure profile. Though the beta limit reduces with the increase of the elongation, the plasma with the peaked pressure profile has larger improvement due to the triangularity than that with the parabolic pressure profile. To access the second stability of the n=1 internal kink mode, the plasma with a flat pressure profile and the large minor radius of the q=1 surface is effective. (author)

  1. Effects of high hydrostatic pressure on genomic expression profiling of porcine parthenogenetic activated and cloned embryos

    DEFF Research Database (Denmark)

    Lin, Lin; Luo, Yonglun; Sørensen, Peter

    2014-01-01

    derived by PA or HMC. Hierarchical clustering depicted stage-specific genomic expression profiling. At the 4-cell and blastocyst stages, 103 and 163 transcripts were differentially expressed between the HMC and PA embryos, respectively (P

  2. Are clusters important in understanding the mechanisms in atmospheric pressure ionization? Part 1: Reagent ion generation and chemical control of ion populations.

    Science.gov (United States)

    Klee, Sonja; Derpmann, Valerie; Wißdorf, Walter; Klopotowski, Sebastian; Kersten, Hendrik; Brockmann, Klaus J; Benter, Thorsten; Albrecht, Sascha; Bruins, Andries P; Dousty, Faezeh; Kauppila, Tiina J; Kostiainen, Risto; O'Brien, Rob; Robb, Damon B; Syage, Jack A

    2014-08-01

    It is well documented since the early days of the development of atmospheric pressure ionization methods, which operate in the gas phase, that cluster ions are ubiquitous. This holds true for atmospheric pressure chemical ionization, as well as for more recent techniques, such as atmospheric pressure photoionization, direct analysis in real time, and many more. In fact, it is well established that cluster ions are the primary carriers of the net charge generated. Nevertheless, cluster ion chemistry has only been sporadically included in the numerous proposed ionization mechanisms leading to charged target analytes, which are often protonated molecules. This paper series, consisting of two parts, attempts to highlight the role of cluster ion chemistry with regard to the generation of analyte ions. In addition, the impact of the changing reaction matrix and the non-thermal collisions of ions en route from the atmospheric pressure ion source to the high vacuum analyzer region are discussed. This work addresses such issues as extent of protonation versus deuteration, the extent of analyte fragmentation, as well as highly variable ionization efficiencies, among others. In Part 1, the nature of the reagent ion generation is examined, as well as the extent of thermodynamic versus kinetic control of the resulting ion population entering the analyzer region.

  3. Signaling pathway-focused gene expression profiling in pressure overloaded hearts

    Directory of Open Access Journals (Sweden)

    Marco Musumeci

    2011-01-01

    Full Text Available The β-blocker propranolol displays antihypertrophic and antifibrotic properties in the heart subjected to pressure overload. Yet the underlying mechanisms responsible for these important effects remain to be completely understood. The purpose of this study was to determine signaling pathway-focused gene expression profile associated with the antihypertrophic action of propranolol in pressure overloaded hearts. To address this question, a focused real-time PCR array was used to screen left ventricular RNA expression of 84 gene transcripts representative of 18 different signaling pathways in C57BL/6 mice subjected to transverse aortic constriction (TAC or sham surgery. On the surgery day, mice received either propranolol (80 mg/kg/day or vehicle for 14 days. TAC caused a 49% increase in the left ventricular weight-to-body weight (LVW/BW ratio without changing gene expression. Propranolol blunted LVW/BW ratio increase by approximately 50% while causing about a 3-fold increase in the expression of two genes, namely Brca1 and Cdkn2a, belonging to the TGF-beta and estrogen pathways, respectively. In conclusion, after 2 weeks of pressure overload, TAC hearts show a gene expression profile superimposable to that of sham hearts. Conversely, propranolol treatment is associated with an increased expression of genes which negatively regulate cell cycle progression. It remains to be established whether a mechanistic link between gene expression changes and the antihypertrophic action of propranolol occurs.

  4. Osmotic pressure-dependent release profiles of payloads from nanocontainers by co-encapsulation of simple salts

    Science.gov (United States)

    Behzadi, Shahed; Rosenauer, Christine; Kappl, Michael; Mohr, Kristin; Landfester, Katharina; Crespy, Daniel

    2016-06-01

    The encapsulation of payloads in micro- to nano-scale capsules allows protection of the payload from the surrounding environment and control of its release profile. Herein, we program the release of hydrophilic payloads from nanocontainers by co-encapsulating simple inorganic salts for adjusting the osmotic pressure. The latter either leads to a burst release at high concentrations of co-encapsulated salts or a sustained release at lower concentrations. Osmotic pressure causes swelling of the nanocapsule's shell and therefore sustained release profiles can be adjusted by crosslinking it. The approach presented allows for programing the release of payloads by co-encapsulating inexpensive salts inside nanocontainers without the help of stimuli-responsive materials.The encapsulation of payloads in micro- to nano-scale capsules allows protection of the payload from the surrounding environment and control of its release profile. Herein, we program the release of hydrophilic payloads from nanocontainers by co-encapsulating simple inorganic salts for adjusting the osmotic pressure. The latter either leads to a burst release at high concentrations of co-encapsulated salts or a sustained release at lower concentrations. Osmotic pressure causes swelling of the nanocapsule's shell and therefore sustained release profiles can be adjusted by crosslinking it. The approach presented allows for programing the release of payloads by co-encapsulating inexpensive salts inside nanocontainers without the help of stimuli-responsive materials. Electronic supplementary information (ESI) available. See DOI: 10.1039/c6nr01882c

  5. Brightest Cluster Galaxies in REXCESS Clusters

    Science.gov (United States)

    Haarsma, Deborah B.; Leisman, L.; Bruch, S.; Donahue, M.

    2009-01-01

    Most galaxy clusters contain a Brightest Cluster Galaxy (BCG) which is larger than the other cluster ellipticals and has a more extended profile. In the hierarchical model, the BCG forms through many galaxy mergers in the crowded center of the cluster, and thus its properties give insight into the assembly of the cluster as a whole. In this project, we are working with the Representative XMM-Newton Cluster Structure Survey (REXCESS) team (Boehringer et al 2007) to study BCGs in 33 X-ray luminous galaxy clusters, 0.055 < z < 0.183. We are imaging the BCGs in R band at the Southern Observatory for Astrophysical Research (SOAR) in Chile. In this poster, we discuss our methods and give preliminary measurements of the BCG magnitudes, morphology, and stellar mass. We compare these BCG properties with the properties of their host clusters, particularly of the X-ray emitting gas.

  6. Distinct pathological profiles of inmates showcasing cluster B personality traits, mental disorders and substance use regarding violent behaviors.

    Science.gov (United States)

    Dellazizzo, Laura; Dugré, Jules R; Berwald, Marieke; Stafford, Marie-Christine; Côté, Gilles; Potvin, Stéphane; Dumais, Alexandre

    2017-12-06

    High rates of violence are found amid offenders with severe mental illnesses (SMI), substance use disorders (SUDs) and Cluster B personality disorders. Elevated rates of comorbidity lead to inconsistencies when it comes to this relationship. Furthermore, overlapping Cluster B personality traits have been associated with violence. Using multiple correspondence analysis and cluster analysis, this study was designed to differentiate profiles of 728 male inmates from penitentiary and psychiatric settings marked by personality traits, SMI and SUDs following different violent patterns. Six significantly differing clusters emerged. Cluster 1, "Sensation seekers", presented recklessness with SUDs and low prevalence's of SMI and auto-aggression. Two clusters committed more sexual offenses. While Cluster 2, "Opportunistic-sexual offenders", had more antisocial lifestyles and SUDs, Cluster 6, "Emotional-sexual offenders", displayed more emotional disturbances with SMI and violence. Clusters 3 and 4, representing "Life-course-persistent offenders", shared early signs of persistent antisocial conduct and severe violence. Cluster 3, "Early-onset violent delinquents", emerged as more severely antisocial with SUDs. Cluster 4, "Early-onset unstable-mentally ill delinquents", were more emotionally driven, with SMI and auto-aggression. Cluster 5, "Late-start offenders", was less severely violent, and emotionally driven with antisocial behavior beginning later. This study suggests the presence of specific psychopathological organizations in violent inmates. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Characterization of atom clusters in irradiated pressure vessel steels and model alloys

    International Nuclear Information System (INIS)

    Auger, P.; Pareige, P.; Akamatsu, M.; Van Duysen, J.C.

    1993-12-01

    In order to characterize the microstructural evolution of the iron solid solution under irradiation, two pressure vessel steels irradiated in service conditions and, for comparison, low copper model alloys irradiated with neutrons and electrons have been studied. The characterization has been carried out mainly thanks to small angle neutron scattering and atom probe experiments. Both techniques lead to the conclusion that clusters develop with irradiations. In Fe-Cu model alloys, copper clusters are formed containing uncertain proportions of iron. In the low copper industrial steels, the feature is more complex. Solute atoms like Ni, Mn and Si, sometimes associated with Cu, segregate as ''clouds'' more or less condensed in the iron solid solution. These silicides, or at least Si, Ni, Mn association, may facilitate the copper segregation although the initial iron matrix contains a low copper concentration. (authors). 24 refs., 3 figs., 2 tabs

  8. Characteristics of Plantar Pressures and Related Pain Profiles in Elite Sprinters and Recreational Runners.

    Science.gov (United States)

    Chow, Tong-Hsien; Chen, Yih-Shyuan; Wang, Jia-Chang

    2018-01-01

    Plantar pressure measurement is effective for assessing plantar loading and can be applied to evaluating foot performance. We sought to explore the characteristics of plantar pressures in elite sprinters and recreational runners during static standing and walking. Arch index (AI) values, regional plantar pressure distributions (PPDs), and footprint characteristics were examined in 80 elite sprinters and 90 recreational runners using an optical plantar pressure measurement system. Elite sprinters' pain profiles were examined to evaluate their most common pain areas. In recreational runners, AI values in males were in the normal range and in females were high arch type. The AI values were significantly lower in elite sprinters than in recreational runners. In elite sprinters, particularly males, the static PPD of both feet was higher at the medial metatarsal bone and the lateral heel and lower at the medial and lateral longitudinal arches. Elite male sprinters' PPD of both feet was mainly transferred to the medial metatarsal bone and decreased at the lateral longitudinal arch and the medial heel during the midstance phase of walking. The lateral knee joint and biceps femoris were the most common sites of musculoskeletal pain in elite sprinters. Elite sprinters' AI values could be classified as high arches, and their PPD tended to parallel the features of runners and high-arched runners. These findings correspond to the profile of patellofemoral pain syndrome (PFPS)-related plantar pressure. The pain profiles seemed to resonate with the symptoms of high-arched runners and PFPS. A possible link between high-arched runners and PFPS warrants further study.

  9. Daily blood pressure profile in Cushing's syndrome before and after surgery

    Directory of Open Access Journals (Sweden)

    Kreze A.

    1999-01-01

    Full Text Available No significant difference has been demonstrated in the altered circadian blood pressure pattern between the pituitary-dependent and adrenal forms of Cushing's syndrome before surgery. The effect of therapy, however, proved to be different. The mesor was normalized in the pituitary-dependent Cushing's syndrome more conspicuously for systolic than for diastolic blood pressure. In Cushing's syndrome due to adrenal adenoma, systolic and diastolic blood pressure mesors have been even significantly "overnormalized" after treatment, being 11 to 27 and 2 to 13 mmHg (95% confidence lower than corresponding mesors in controls. There was no difference between forms in the effect of treatment on blood pressure amplitudes, which remained significantly lower than in controls. Finally, acrophase patterns were partly normalized after treatment of the pituitary-dependent form only for diastolic blood pressure, while both systolic and diastolic blood pressure acrophases were normalized in the treated adrenal form. In conclusion, complete normalization of the pattern of daily blood pressure profile has not been achieved in either form of the syndrome. This may be one of the reasons for the reduced long-term survival after surgical cure of hypercortisolism, than expected.

  10. The use of cluster analysis method for the localization of acoustic emission sources detected during the hydrotest of PWR pressure vessels

    International Nuclear Information System (INIS)

    Liska, J.; Svetlik, M.; Slama, K.

    1982-01-01

    The acoustic emission method is a promising tool for checking reactor pressure vessel integrity. Localization of emission sources is the first and the most important step in processing emission signals. The paper describes the emission sources localization method which is based on cluster analysis of a set of points depicting the emission events in the plane of coordinates of their occurrence. The method is based on using this set of points for constructing the minimum spanning tree and its partition into fragments corresponding to point clusters. Furthermore, the laws are considered of probability distribution of the minimum spanning tree edge length for one and several clusters with the aim of finding the optimum length of the critical edge for the partition of the tree. Practical application of the method is demonstrated on localizing the emission sources detected during a hydrotest of a pressure vessel used for testing the reactor pressure vessel covers. (author)

  11. Simultaneous real-time control of the current and pressure profiles in JET: experiments and modelling

    Energy Technology Data Exchange (ETDEWEB)

    Mazon, D.; Laborde, L.; Litaudon, X.; Moreau, D.; Zabeo, L.; Joffrin, E. [Association Euratom-CEA Cadarache (DSM/DRFC), 13 - Saint-Paul-lez-Durance (France). Dept. de Recherches sur la Fusion Controlee; Murari, A. [Consorzio RFX Association Euratom-ENEA, Padova (Italy); Ariola, M.; Albanese, R.; Tommasi, G. de; Pironti, A. [Association Euratom-ENEA, CREATE, Napoly (Italy); Moreau, D. [EFDA-JET CSU, Culham Science Centre, Abingdon, OX (United Kingdom); Tala, T. [Euratom-Tekes Association, VTT Processes (Finland); Crisanti, F.; Pericoli-Ridolfini, V.; Tuccillo, A. [Association Euratom-ENEA, C.R. Frascati (Italy); Baar, M. de; Vries, P. de [Euratom-FOM Association, TEC Cluster, Nieuwegein (Netherlands); De la Luna, E. [Euratom-Ciemat Association (Spain); Felton, R.; Corrigan, G. [Euratom-UKAEA Association, Culham Science Centre, Abingdon (United Kingdom)

    2004-07-01

    Real-time control of the plasma profiles (current density, pressure and flow) is one of the major issues for sustaining internal transport barriers (ITB) in a high performance plasma, with a large bootstrap current fraction. We have recently investigated the experimental and numerical aspects of the simultaneous control of the current and pressure profiles in JET ITB discharges. The current density and the electron temperature were successfully controlled via the safety factor profile (or via its inverse the tau-profile) and the {rho}{sup *}{sub Te} profile respectively. The results of these new studies are presented. With only a limited number of actuators, the technique aims at minimizing an integral square error signal which combines the 2 profiles, rather than attempting to control plasma parameters at some given radii with great precision. The resulting fuzziness of the control scheme allows the plasma to relax towards a physically accessible non-linear state which may not be accurately known in advance, but is close enough to the requested one to provide the required plasma performance. Closed loop experiments have allow to reach different target q and {rho}{sup *}{sub Te} profiles, and to some degree, to displace the region of maximum electron temperature gradient. The control has also shown some robustness in front of rapid transients.

  12. Clustering of Multiple Lifestyle Behaviours and Its Association to Cardiovascular Risk Factors in Children

    DEFF Research Database (Denmark)

    Bel-Serrat, Silvia; Mouratidou, Theodora; Santaliestra-Pasías, Alba María

    2013-01-01

    ratio, triglycerides, sum of two skinfolds and systolic blood pressure (SBP) z-scores were summed to compute a CVD risk score. Cluster analyses stratified by sex and age groups (2 to ...) consumption, PA performance and television video/DVD viewing. RESULTS: Five clusters were identified. Associations between CVD risk factors and score, and clusters were obtained by multiple linear regression using cluster 5 (‘low beverages consumption and low sedentary’) as the reference cluster. SBP...... association was observed between CVD risk score and clusters 2 (β=0.60; 95% CI: 0.20, 1.01), 3 (β=0.55; 95% CI: 0.14, 0.97) and 4 (β=0.60, 95% CI: 0.18, 1.02) in older boys. CONCLUSIONS: Low television/video/DVD viewing levels and low SSB consumption may result in a healthier CVD profile rather than having...

  13. The XMM Cluster Outskirts Project (X-COP): Thermodynamic properties of the intracluster medium out to R200 in Abell 2319

    Science.gov (United States)

    Ghirardini, V.; Ettori, S.; Eckert, D.; Molendi, S.; Gastaldello, F.; Pointecouteau, E.; Hurier, G.; Bourdin, H.

    2018-06-01

    Aims: We present the joint analysis of the X-ray and Sunyaev-Zel'dovich (SZ) signals in Abell 2319, the galaxy cluster with the highest signal-to-noise ratio in SZ Planck maps and that has been surveyed within our XMM-Newton Cluster Outskirts Project (X-COP), a very large program which aims to grasp the physical condition in 12 local (z 3 × 1014 M⊙) galaxy clusters out to R200 and beyond. Methods: We recover the profiles of the thermodynamic properties by the geometrical deprojection of the X-ray surface brightness, of the SZ Comptonization parameter, and accurate and robust spectroscopic measurements of the gas temperature out to 3.2 Mpc (1.6 R200), 4 Mpc (2 R200), and 1.6 Mpc (0.8 R200), respectively. We resolve the clumpiness of the gas density to be below 20% over the entire observed volume. We also demonstrate that most of this clumpiness originates from the ongoing merger and can be associated with large-scale inhomogeneities (the "residual" clumpiness). We estimate the total mass through the hydrostatic equilibrium equation. This analysis is done both in azimuthally averaged radial bins and in eight independent angular sectors, enabling us to study in detail the azimuthal variance of the recovered properties. Results: Given the exquisite quality of the X-ray and SZ datasets, their radial extension, and their complementarity, we constrain at R200 the total hydrostatic mass, modelled with a Navarro-Frenk-White profile at very high precision (M200 = 10.7 ± 0.5stat. ± 0.9syst. × 1014 M⊙). We identify the ongoing merger and how it is affecting differently the gas properties in the resolved azimuthal sectors. We have several indications that the merger has injected a high level of non-thermal pressure in this system: the clumping free density profile is above the average profile obtained by stacking Rosat/PSPC observations; the gas mass fraction recovered using our hydrostatic mass profile exceeds the expected cosmic gas fraction beyond R500; the pressure

  14. CLASH-VLT: The stellar mass function and stellar mass density profile of the z=0.44 cluster of galaxies MACS J1206.2-0847

    CERN Document Server

    Annunziatella, M; Mercurio, A.; Nonino, M.; Rosati, P.; Balestra, I.; Presotto, V.; Girardi, M.; Gobat, R.; Grillo, C.; Medezinski, E.; Kelson, D.; Postman, M.; Scodeggio, M.; Brescia, M.; Sartoris, B.; Demarco, R.; Fritz, A.; Koekemoer, A.; Lemze, D.; Lombardi, M.; Bradley, L.; Coe, D.; Donahue, M.; Regös, E.; Umetsu, K.; Vanzella, E.; Infante, L.; Kuchner, U.; Maier, C.; Verdugo, M.; Ziegler, B.

    2014-01-01

    Context. The study of the galaxy stellar mass function (SMF) in relation to the galaxy environment and the stellar mass density profile, rho(r), is a powerful tool to constrain models of galaxy evolution. Aims. We determine the SMF of the z=0.44 cluster of galaxies MACS J1206.2-0847 separately for passive and star-forming (SF) galaxies, in different regions of the cluster, from the center out to approximately 2 virial radii. We also determine rho(r) to compare it to the number density and total mass density profiles. Methods. We use the dataset from the CLASH-VLT survey. Stellar masses are obtained by SED fitting on 5-band photometric data obtained at the Subaru telescope. We identify 1363 cluster members down to a stellar mass of 10^9.5 Msolar. Results. The whole cluster SMF is well fitted by a double Schechter function. The SMFs of cluster SF and passive galaxies are statistically different. The SMF of the SF cluster galaxies does not depend on the environment. The SMF of the passive population has a signif...

  15. Rapid formation of electric field profiles in repetitively pulsed high-voltage high-pressure nanosecond discharges

    International Nuclear Information System (INIS)

    Ito, Tsuyohito; Kobayashi, Kazunobu; Hamaguchi, Satoshi; Czarnetzki, Uwe

    2010-01-01

    Rapid formation of electric field profiles has been observed directly for the first time in nanosecond narrow-gap parallel-plate discharges at near-atmospheric pressure. The plasmas examined here are of hydrogen, and the field measurement is based on coherent Raman scattering (CRS) by hydrogen molecules. Combined with the observation of spatio-temporal light emission profiles by a high speed camera, it has been found that the rapid formation of a high-voltage thin cathode sheath is accompanied by fast propagation of an ionization front from a region near the anode. Unlike well-known parallel-plate discharges at low pressure, the discharge formation process at high pressure is almost entirely driven by electron dynamics as ions and neutral species are nearly immobile during the rapid process. (fast track communication)

  16. Base Flow and Heat Transfer Characteristics of a Four-Nozzle Clustered Rocket Engine: Effect of Nozzle Pressure Ratio

    Science.gov (United States)

    Nallasamy, R.; Kandula, M.; Duncil, L.; Schallhorn, P.

    2010-01-01

    The base pressure and heating characteristics of a four-nozzle clustered rocket configuration is studied numerically with the aid of OVERFLOW Navier-Stokes code. A pressure ratio (chamber pressure to freestream static pressure) range of 990 to 5,920 and a freestream Mach number range of 2.5 to 3.5 are studied. The qualitative trends of decreasing base pressure with increasing pressure ratio and increasing base heat flux with increasing pressure ratio are correctly predicted. However, the predictions for base pressure and base heat flux show deviations from the wind tunnel data. The differences in absolute values between the computation and the data are attributed to factors such as perfect gas (thermally and calorically perfect) assumption, turbulence model inaccuracies in the simulation, and lack of grid adaptation.

  17. Development of a cluster-jet target for PANDA

    International Nuclear Information System (INIS)

    Gruber, A.; Marton, J.; Widmann, E.; Zmeskal, J.; Orth, H.; Luehning, J.

    2008-01-01

    Full text: The Stefan Meyer Institut (SMI) is part of the international PANDA collaboration. The universal detector will be constructed at the future high-energy antiproton storage ring HESR at FAIR (Facility for Antiproton and Ion Research, GSI/Darmstadt). PANDA will use antiproton beams (1.5 to 15 GeV/c) for hadron physics in the charmonium region. The physics program of PANDA will encompass charmonium spectroscopy below and above open charm threshold, search for exotics (glueballs, hybrids), lambda and double-lambda hypernuclei studies and the investigation of in-medium modifications of charmed mesons - an experimentally unexplored field. SMI contributes to major parts of the PANDA detector like the hydrogen cluster-jet target and the vacuum system of the antiproton - target interaction zone. In order to reach the desired target density, an optimization of the cold head, the nozzle and the skimmer arrangement is essential. A density-profile monitor for the cluster-jet was designed and built at SMI. Several nozzle types will be studied using different gases, temperatures and inlet pressures. Additionally we, together with the cluster-jet target group at GSI, are carrying out R and D for improving the jet-density. The Genova/Fermilab cluster-jet target used for these measurements has been in use at Fermilab for the experiments E760 and E835 and has been transferred to GSI for this purpose. The setup of the density-profile monitor at SMI and several measurements at GSI will be presented. (author)

  18. Optimal Selection of Clustering Algorithm via Multi-Criteria Decision Analysis (MCDA for Load Profiling Applications

    Directory of Open Access Journals (Sweden)

    Ioannis P. Panapakidis

    2018-02-01

    Full Text Available Due to high implementation rates of smart meter systems, considerable amount of research is placed in machine learning tools for data handling and information retrieval. A key tool in load data processing is clustering. In recent years, a number of researches have proposed different clustering algorithms in the load profiling field. The present paper provides a methodology for addressing the aforementioned problem through Multi-Criteria Decision Analysis (MCDA and namely, using the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS. A comparison of the algorithms is employed. Next, a single test case on the selection of an algorithm is examined. User specific weights are applied and based on these weight values, the optimal algorithm is drawn.

  19. Applications of Cluster Analysis to the Creation of Perfectionism Profiles: A Comparison of two Clustering Approaches

    Directory of Open Access Journals (Sweden)

    Jocelyn H Bolin

    2014-04-01

    Full Text Available Although traditional clustering methods (e.g., K-means have been shown to be useful in the social sciences it is often difficult for such methods to handle situations where clusters in the population overlap or are ambiguous. Fuzzy clustering, a method already recognized in many disciplines, provides a more flexible alternative to these traditional clustering methods. Fuzzy clustering differs from other traditional clustering methods in that it allows for a case to belong to multiple clusters simultaneously. Unfortunately, fuzzy clustering techniques remain relatively unused in the social and behavioral sciences. The purpose of this paper is to introduce fuzzy clustering to these audiences who are currently relatively unfamiliar with the technique. In order to demonstrate the advantages associated with this method, cluster solutions of a common perfectionism measure were created using both fuzzy clustering and K-means clustering, and the results compared. Results of these analyses reveal that different cluster solutions are found by the two methods, and the similarity between the different clustering solutions depends on the amount of cluster overlap allowed for in fuzzy clustering.

  20. Applications of cluster analysis to the creation of perfectionism profiles: a comparison of two clustering approaches.

    Science.gov (United States)

    Bolin, Jocelyn H; Edwards, Julianne M; Finch, W Holmes; Cassady, Jerrell C

    2014-01-01

    Although traditional clustering methods (e.g., K-means) have been shown to be useful in the social sciences it is often difficult for such methods to handle situations where clusters in the population overlap or are ambiguous. Fuzzy clustering, a method already recognized in many disciplines, provides a more flexible alternative to these traditional clustering methods. Fuzzy clustering differs from other traditional clustering methods in that it allows for a case to belong to multiple clusters simultaneously. Unfortunately, fuzzy clustering techniques remain relatively unused in the social and behavioral sciences. The purpose of this paper is to introduce fuzzy clustering to these audiences who are currently relatively unfamiliar with the technique. In order to demonstrate the advantages associated with this method, cluster solutions of a common perfectionism measure were created using both fuzzy clustering and K-means clustering, and the results compared. Results of these analyses reveal that different cluster solutions are found by the two methods, and the similarity between the different clustering solutions depends on the amount of cluster overlap allowed for in fuzzy clustering.

  1. Marketing research cluster analysis

    OpenAIRE

    Marić Nebojša

    2002-01-01

    One area of applications of cluster analysis in marketing is identification of groups of cities and towns with similar demographic profiles. This paper considers main aspects of cluster analysis by an example of clustering 12 cities with the use of Minitab software.

  2. Microgrids Real-Time Pricing Based on Clustering Techniques

    Directory of Open Access Journals (Sweden)

    Hao Liu

    2018-05-01

    Full Text Available Microgrids are widely spreading in electricity markets worldwide. Besides the security and reliability concerns for these microgrids, their operators need to address consumers’ pricing. Considering the growth of smart grids and smart meter facilities, it is expected that microgrids will have some level of flexibility to determine real-time pricing for at least some consumers. As such, the key challenge is finding an optimal pricing model for consumers. This paper, accordingly, proposes a new pricing scheme in which microgrids are able to deploy clustering techniques in order to understand their consumers’ load profiles and then assign real-time prices based on their load profile patterns. An improved weighted fuzzy average k-means is proposed to cluster load curve of consumers in an optimal number of clusters, through which the load profile of each cluster is determined. Having obtained the load profile of each cluster, real-time prices are given to each cluster, which is the best price given to all consumers in that cluster.

  3. Simulations of the pressure profiles of the PETRAIII frontends

    International Nuclear Information System (INIS)

    Amann, C; Uhahn; Hesse, M; Schulte-Schrepping, H

    2008-01-01

    PETRA III will be a high brilliance third generation synchrotron radiation source. The undulators will provide photon beams with small beam size and therefore the components in the frontend are as compact as feasible. The resulting narrow cross sections of the vacuum system will yield a small conductance in the whole beamline. The design of the frontends has reached an advanced state so that the initial design of the vacuum system can be finalized now. The vacuum specification of the beamline components demands for a hydrocarbon and dust free vacuum systems. To provide this, the beamline will be initially pumped down with dry pumping stations to a pressure of at least 10 -6 mbar. At this pressure a set of ion pumps will be switched on to pump the beamline continuously. For lifetime reasons of the ion pumps it is necessary that during operation the pressure in the pumps is below 10 -6 mbar. During the start up of the beamline system a high amount of gas will be photo desorbed especially at the high power slit systems. To cope with this, the pumping concept of the beamline has been revised. Monte Carlo simulations of the pressure profiles in the beamline show that additional pumping near the slit systems is mandatory for a long lifetime of the ion-pumps. The paper reports the layout process of the pumping system

  4. Aero thermal test results obtained on the n. C 5 EL 4 Cluster in the atmospheric pressure cell

    International Nuclear Information System (INIS)

    Gasc, B.

    1964-01-01

    In the framework of thermal studies on the EL-4 cluster, the full-scale tests at atmospheric pressure are designed to permit measurement of local values of the wall temperature, of the velocity and of the temperature in the fluid. The experimental results, obtained with the help of an original measuring apparatus, make it possible to follow the changes in these values along the cluster and to predict in much detail the in-pile thermal behaviour. In particular it is shown that changes in the wall temperature along the cluster are greatly influenced by disruption of the flow caused by grids and supports. (author) [fr

  5. Burnout correlations for even- and odd-numbered peripheral rod clusters over low pressure range

    International Nuclear Information System (INIS)

    Akaho, E.H.K.

    1995-01-01

    Burnout data with low pressure Freon-113 for even- and odd- numbered peripheral rod clusters with relatively large spacings were used to derive equations in terms of dimensionless parameters suggested by Barnett. The equations which are for three different flow regimes for each rod geometry (even or odd) were found to predict burnout data with maximum RMS deviation being 3.8%. (author). 11 figs., 3 tabs., 15 refs

  6. Marketing research cluster analysis

    Directory of Open Access Journals (Sweden)

    Marić Nebojša

    2002-01-01

    Full Text Available One area of applications of cluster analysis in marketing is identification of groups of cities and towns with similar demographic profiles. This paper considers main aspects of cluster analysis by an example of clustering 12 cities with the use of Minitab software.

  7. JET steady state ITB operation with active control of the pressure profile

    Energy Technology Data Exchange (ETDEWEB)

    Crisanti, F.; Litaudon, X.; Mailloux, J. [and others

    2002-07-01

    Stationary operations have been achieved at JET in ITBs scenarios, with the discharge time limited only by plant constraints. Full current drive was obtained, all over the high performance phase, with the current density profile frozen by using Lower Hybrid current drive. For the first time a feed-back control on the total pressure and on the electron temperature profile was implemented by using respectively the Neutral Beams and the Ion Cyclotron waves. Although impurity accumulation could be a problem in steady state ITBs, these experiments bring some elements to answer to it. Tokamak operation in enhanced confinement regimes, characterized by edge and/or Internal Transport Barriers (respectively known as H-mode and ITB), is attractive as it represents an important step towards the approach of ignition conditions. Moreover, the necessity of steady state operation in a Tokamak reactor, has led to the concept of the Advanced Tokamak, in which the current density profile is no longer tied to the plasma conductivity and is non inductively driven. Since the bootstrap current is a consequence of the pressure gradient, one of the primary goal of the Advanced Tokamak studies is to maximize the bootstrap fraction, with a proper alignment, both in H mode and in ITB regimes. However, for several reasons, it is difficult to envisage an operational situation in which the bootstrap fraction is close to 100%: for instance, there are few chances of pressure or/and current profile control to optimize the MHD stability. So far, various experiments have been performed with improved confinement regimes lasting up to tens of the confinement time and up to some current relaxation times. In some experiments a large non inductive plasma current (< 75%) was obtained with about 50% from bootstrap and 25% from Neutral Beam Injection (NBI); however, no full current drive operation was achieved and, moreover, with the available heating systems, no active feedback control of the current

  8. Limited evidence of abnormal intra-colonic pressure profiles in diverticular disease - a systematic review.

    Science.gov (United States)

    Jaung, R; Robertson, J; O'Grady, G; Milne, T; Rowbotham, D; Bissett, I P

    2017-06-01

    Abnormal colonic pressure profiles and high intraluminal pressures are postulated to contribute to the formation of sigmoid colon diverticulosis and the pathophysiology of diverticular disease. This study aimed to review evidence for abnormal colonic pressure profiles in diverticulosis. All published studies investigating colonic pressure in patients with diverticulosis were searched in three databases (Medline, Embase, Scopus). No language restrictions were applied. Any manometry studies in which patients with diverticulosis were compared with controls were included. The Newcastle-Ottawa Quality Assessment Scale (NOS) for case-control studies was used as a measure of risk of bias. A cut-off of five or more points on the NOS (fair quality in terms of risk of bias) was chosen for inclusion in the meta-analysis. Ten studies (published 1962-2005) met the inclusion criteria. The studies followed a wide variety of protocols and all used low-resolution manometry (sensor spacing range 7.5-15 cm). Six studies compared intra-sigmoid pressure, with five of six showing higher pressure in diverticulosis vs controls, but only two reached statistical significance. A meta-analysis was not performed as only two studies were above the cut-off and these did not have comparable outcomes. This systematic review of manometry data shows that evidence for abnormal pressure in the sigmoid colon in patients with diverticulosis is weak. Existing studies utilized inconsistent methodology, showed heterogeneous results and are of limited quality. Higher quality studies using modern manometric techniques and standardized reporting methods are needed to clarify the role of colonic pressure in diverticulosis. Colorectal Disease © 2017 The Association of Coloproctology of Great Britain and Ireland.

  9. Subaru Weak Lensing Measurements of Four Strong Lensing Clusters: Are Lensing Clusters Over-Concentrated?

    Energy Technology Data Exchange (ETDEWEB)

    Oguri, Masamune; Hennawi, Joseph F.; Gladders, Michael D.; Dahle, Haakon; Natarajan, Priyamvada; Dalal, Neal; Koester, Benjamin P.; Sharon, Keren; Bayliss, Matthew

    2009-01-29

    We derive radial mass profiles of four strong lensing selected clusters which show prominent giant arcs (Abell 1703, SDSS J1446+3032, SDSS J1531+3414, and SDSS J2111-0115), by combining detailed strong lens modeling with weak lensing shear measured from deep Subaru Suprime-cam images. Weak lensing signals are detected at high significance for all four clusters, whose redshifts range from z = 0.28 to 0.64. We demonstrate that adding strong lensing information with known arc redshifts significantly improves constraints on the mass density profile, compared to those obtained from weak lensing alone. While the mass profiles are well fitted by the universal form predicted in N-body simulations of the {Lambda}-dominated cold dark matter model, all four clusters appear to be slightly more centrally concentrated (the concentration parameters c{sub vir} {approx} 8) than theoretical predictions, even after accounting for the bias toward higher concentrations inherent in lensing selected samples. Our results are consistent with previous studies which similarly detected a concentration excess, and increases the total number of clusters studied with the combined strong and weak lensing technique to ten. Combining our sample with previous work, we find that clusters with larger Einstein radii are more anomalously concentrated. We also present a detailed model of the lensing cluster Abell 1703 with constraints from multiple image families, and find the dark matter inner density profile to be cuspy with the slope consistent with -1, in agreement with expectations.

  10. Radial profiles of velocity and pressure for condensation-induced hurricanes

    International Nuclear Information System (INIS)

    Makarieva, A.M.; Gorshkov, V.G.

    2011-01-01

    The Bernoulli integral in the form of an algebraic equation is obtained for the hurricane air flow as the sum of the kinetic energy of wind and the condensational potential energy. With an account for the eye rotation energy and the decrease of angular momentum towards the hurricane center it is shown that the theoretical profiles of pressure and velocity agree well with observations for intense hurricanes. The previous order of magnitude estimates obtained in pole approximation are confirmed.

  11. Radial profiles of velocity and pressure for condensation-induced hurricanes

    Science.gov (United States)

    Makarieva, A. M.; Gorshkov, V. G.

    2011-02-01

    The Bernoulli integral in the form of an algebraic equation is obtained for the hurricane air flow as the sum of the kinetic energy of wind and the condensational potential energy. With an account for the eye rotation energy and the decrease of angular momentum towards the hurricane center it is shown that the theoretical profiles of pressure and velocity agree well with observations for intense hurricanes. The previous order of magnitude estimates obtained in pole approximation are confirmed.

  12. Radial profiles of velocity and pressure for condensation-induced hurricanes

    Energy Technology Data Exchange (ETDEWEB)

    Makarieva, A.M., E-mail: ammakarieva@gmail.co [Theoretical Physics Division, Petersburg Nuclear Physics Institute, Gatchina, St. Petersburg (Russian Federation); Gorshkov, V.G. [Theoretical Physics Division, Petersburg Nuclear Physics Institute, Gatchina, St. Petersburg (Russian Federation)

    2011-02-14

    The Bernoulli integral in the form of an algebraic equation is obtained for the hurricane air flow as the sum of the kinetic energy of wind and the condensational potential energy. With an account for the eye rotation energy and the decrease of angular momentum towards the hurricane center it is shown that the theoretical profiles of pressure and velocity agree well with observations for intense hurricanes. The previous order of magnitude estimates obtained in pole approximation are confirmed.

  13. Blood pressure and lipid profiles in adolescents with hypertensive parents

    Directory of Open Access Journals (Sweden)

    Julia Fitriany

    2016-11-01

    Full Text Available Background Adolescent hypertension is a significant health problem of increasing prevalence and causes high morbidity and mortality. It is found primarily in young males, with a familial history of hypertension and/or cardiovascular disease. Examination of lipid profiles has been used to detect the risk of hypertension in adolescents. Objective To compare blood pressure and lipid profiles in adolescents with and without a parental history of hypertension. Methods This cross-sectional study was conducted from January to February 2012 on students from a senior high school in the Toba Samosir District, North Sumatera. Sixty-eight adolescents were included, aged 15 to 18 years. Group I comprised 34 adolescents with hypertensive parents, and group II comprised 34 adolescents with normotensive parents. Subjects were selected based on questionnaires. Subjects’ blood pressures were measured at rest. Three measurements were made in intervals of 10-15 minutes, then averaged for both systolic and diastolic blood pressures. Lipid profiles were measured using the CardioCheck cholesterol test after subjects had fasted for 12 hours. Results The median systolic blood pressures (SBP in groups I and II were 110 mmHg (range 93.3-123.3 and 106.7 mmHg (range 96.7-123.3, respectively, (P=0.584. The median diastolic blood pressures (DBP were 73.3 mmHg (range 66.7-83.3 and 71.7 mmHg (range 63.3-80.0, respectively, (P=0.953. Total cholesterol and low-density lipoprotein cholesterol (LDL-C levels in group I were significantly higher than those levels in group II [median total cholesterol: 162.0 (range 158-170 vs. 159.0 (range 150-170, respectively; (P=0.001; and mean LDL-C: 103.5 (SD 3.72 vs. 99.1 (SD 4.63, respectively; (P=0.001. Multivariate analysis revealed a correlation of moderate strength between parental history of hypertension and increased LDL-C (P<0.001 in adolescents. Conclusion Adolescents with and without familial history of hypertension have no

  14. [Salt intake profile and blood pressure in cystic fibrosis].

    Science.gov (United States)

    Campuzano Martín, S H; Díaz Martín, J J; Perillán Méndez, C; Argüelles Luis, J; Vijande Vázquez, M; Málaga Guerrero, S

    2009-05-01

    High blood pressure (BP) is not considered a problem in patients with cystic fibrosis (CF). The loss of sodium in these patients may affect their sensitivity to the taste of salt. To study the BP in a group of patients with CF and to analyse their salt intake profile and the relationship with their BP levels. Cross-sectional analytical study with control group. Index group: 20 subjects, 4-30 years old with diagnosis of CF. 73 healthy subjects. Physical examination, BP measurement and specific tests to determine the salt ingestion profile. Systolic BP (SBP) and diastolic BP (DBP) values were lower in the CF group. SBP: 99.63+/-9.11mmHg vs. 111.94+/-10.71mmHg, P: 0.001. DBP: 57.84+/-7.40mmHg vs. 70.05+/-8.11mmHg, P: 0.001. When these values were adjusted for age, sex, weight and height of the participants, differences did not remain statistically significant. Values of the salt intake profile did not differ significantly between the two groups. While the control group showed a significant negative correlation between SBP and salt taste sensitivity (r: -0.341, P=0.003), this correlation was not confirmed in CF patients (r: -0.115 P=0.6). BP values and the salt intake profile values in CF patients are equivalent to the normal population values when their differences are adjusted to the potential confounding factors. There is no correlation between BP levels and salt taste sensitivity in patients with CF.

  15. Jellyfish: the origin and distribution of extreme ram-pressure stripping events in massive galaxy clusters

    Science.gov (United States)

    McPartland, Conor; Ebeling, Harald; Roediger, Elke; Blumenthal, Kelly

    2016-01-01

    We investigate the observational signatures and physical origin of ram-pressure stripping (RPS) in 63 massive galaxy clusters at z = 0.3-0.7, based on images obtained with the Hubble Space Telescope. Using a training set of a dozen `jellyfish' galaxies identified earlier in the same imaging data, we define morphological criteria to select 211 additional, less obvious cases of RPS. Spectroscopic follow-up observations of 124 candidates so far confirmed 53 as cluster members. For the brightest and most favourably aligned systems, we visually derive estimates of the projected direction of motion based on the orientation of apparent compression shocks and debris trails. Our findings suggest that the onset of these events occurs primarily at large distances from the cluster core (>400 kpc), and that the trajectories of the affected galaxies feature high-impact parameters. Simple models show that such trajectories are highly improbable for galaxy infall along filaments but common for infall at high velocities, even after observational biases are accounted for, provided the duration of the resulting RPS events is ≲500 Myr. We thus tentatively conclude that extreme RPS events are preferentially triggered by cluster mergers, an interpretation that is supported by the disturbed dynamical state of many of the host clusters. This hypothesis implies that extreme RPS might occur also near the cores of merging poor clusters or even merging groups of galaxies. Finally, we present nine additional `jellyfish" galaxies at z > 0.3 discovered by us, thereby doubling the number of such systems known at intermediate redshift.

  16. Accelerating Information Retrieval from Profile Hidden Markov Model Databases.

    Science.gov (United States)

    Tamimi, Ahmad; Ashhab, Yaqoub; Tamimi, Hashem

    2016-01-01

    Profile Hidden Markov Model (Profile-HMM) is an efficient statistical approach to represent protein families. Currently, several databases maintain valuable protein sequence information as profile-HMMs. There is an increasing interest to improve the efficiency of searching Profile-HMM databases to detect sequence-profile or profile-profile homology. However, most efforts to enhance searching efficiency have been focusing on improving the alignment algorithms. Although the performance of these algorithms is fairly acceptable, the growing size of these databases, as well as the increasing demand for using batch query searching approach, are strong motivations that call for further enhancement of information retrieval from profile-HMM databases. This work presents a heuristic method to accelerate the current profile-HMM homology searching approaches. The method works by cluster-based remodeling of the database to reduce the search space, rather than focusing on the alignment algorithms. Using different clustering techniques, 4284 TIGRFAMs profiles were clustered based on their similarities. A representative for each cluster was assigned. To enhance sensitivity, we proposed an extended step that allows overlapping among clusters. A validation benchmark of 6000 randomly selected protein sequences was used to query the clustered profiles. To evaluate the efficiency of our approach, speed and recall values were measured and compared with the sequential search approach. Using hierarchical, k-means, and connected component clustering techniques followed by the extended overlapping step, we obtained an average reduction in time of 41%, and an average recall of 96%. Our results demonstrate that representation of profile-HMMs using a clustering-based approach can significantly accelerate data retrieval from profile-HMM databases.

  17. The shape of velocity dispersion profiles and the dynamical state of galaxy clusters

    Science.gov (United States)

    Costa, A. P.; Ribeiro, A. L. B.; de Carvalho, R. R.

    2018-01-01

    Motivated by the existence of the relationship between the dynamical state of clusters and the shape of the velocity dispersion profiles (VDPs), we study the VDPs for Gaussian (G) and non-Gaussian (NG) systems for a subsample of clusters from the Yang catalogue. The groups cover a redshift interval of 0.03 ≤ z ≤ 0.1 with halo mass ≥1014 M⊙. We use a robust statistical method, Hellinger Distance, to classify the dynamical state of the systems according to their velocity distribution. The stacked VDP of each class, G and NG, is then determined using either Bright or Faint galaxies. The stacked VDP for G groups displays a central peak followed by a monotonically decreasing trend which indicates a predominance of radial orbits, with the Bright stacked VDP showing lower velocity dispersions in all radii. The distinct features we find in NG systems are manifested not only by the characteristic shape of VDP, with a depression in the central region, but also by a possible higher infall rate associated with galaxies in the Faint stacked VDP.

  18. Measurements of Pfirsch-Schlueter current and pressure profile for the high density ECH plasmas in Heliotron DR

    International Nuclear Information System (INIS)

    Morimoto, S.; Yanagi, N.; Nakasuga, M.; Obiki, T.; Iiyoshi, A.; Uo, K.

    1988-01-01

    The Pfirsch-Schlueter current and pressure profiles are estimated from magnetic measurements for high density electron cyclotron heating (ECH) plasmas (n-bar e =(2-3)x10 13 cm -3 , T e0 =200-400 eV, (β) 0 (1-(r/a) 2 ) s , is about two in macroscopically stable plasmas. A fast loss of plasma energy from the centre to the periphery is observed during the onset of the MHD instability. This method of measuring the pressure profile shape is simple and useful for heliotron type devices. (author). 20 refs, 8 figs, 1 tab

  19. High Temperature- and High Pressure-Processed Garlic Improves Lipid Profiles in Rats Fed High Cholesterol Diets

    Science.gov (United States)

    Sohn, Chan Wok; Kim, Hyunae; You, Bo Ram; Kim, Min Jee; Kim, Hyo Jin; Lee, Ji Yeon; Sok, Dai-Eun; Kim, Jin Hee; Lee, Kun Jong

    2012-01-01

    Abstract Garlic protects against degenerative diseases such as hyperlipidemia and cardiovascular diseases. However, raw garlic has a strong pungency, which is unpleasant. In this study, we examined the effect of high temperature/high pressure-processed garlic on plasma lipid profiles in rats. Sprague–Dawley rats were fed a normal control diet, a high cholesterol (0.5% cholesterol) diet (HCD) only, or a high cholesterol diet supplemented with 0.5% high temperature/high pressure-processed garlic (HCP) or raw garlic (HCR) for 10 weeks. The body weights of the rats fed the garlic-supplemented diets decreased, mostly because of reduced fat pad weights. Plasma levels of total cholesterol (TC), low-density lipoprotein cholesterol, and triglyceride (TG) in the HCP and HCR groups decreased significantly compared with those in the HCD group. Additionally, fecal TC and TG increased significantly in the HCP and HCR groups. It is notable that no significant differences in plasma or fecal lipid profiles were observed between the HCP and HCR groups. High temperature/high pressure-processed garlic contained a higher amount of S-allyl cysteine than raw garlic (Pgarlic may be useful as a functional food to improve lipid profiles. PMID:22404600

  20. The mechanism of solute-enriched clusters formation in neutron-irradiated pressure vessel steels: The case of Fe-Cu model alloys

    Energy Technology Data Exchange (ETDEWEB)

    Subbotin, A.V., E-mail: Alexey.V.Subbotin@gmail.com [Scientific and Production Complex Atomtechnoprom, Moscow 119180 (Russian Federation); Panyukov, S.V., E-mail: panyukov@lpi.ru [PN Lebedev Physics Institute, Russian Academy of Sciences, Moscow 117924 (Russian Federation)

    2016-08-15

    Mechanism of solute-enriched clusters formation in neutron-irradiated pressure vessel steels is proposed and developed in case of Fe-Cu model alloys. The suggested solute-drag mechanism is analogous to the well-known zone-refining process. We show that the obtained results are in good agreement with available experimental data on the parameters of clusters enriched with the alloying elements. Our model explains why the formation of solute-enriched clusters does not happen in austenitic stainless steels with fcc lattice structure. It also allows to quantify the method of evaluation of neutron irradiation dose for the process of RPV steels hardening.

  1. Radial profile of pressure in a storm ring current as a function of D st

    Science.gov (United States)

    Kovtyukh, A. S.

    2010-06-01

    Using satellite data obtained near the equatorial plane during 12 magnetic storms with amplitudes from -61 down to -422 nT, the dependences of maximum in L-profile of pressure ( L m) of the ring current (RC) on the current value of D st are constructed, and their analytical approximations are derived. It is established that function L m( D st ) is steeper on the phase of recovery than during the storm’s main phase. The form of the outer edge of experimental radial profiles of RC pressure is studied, and it is demonstrated to correspond to exponential growth of the total energy of RC particles on a given L shell with decreasing L. It is shown that during the storms’ main phase the ratio of plasma and magnetic field pressures at the RC maximum does not practically depend on the storm strength and L m value. This fact reflects resistance of the Earth’s magnetic field to RC expansion, and testifies that during storms the possibilities of injection to small L are limited for RC particles. During the storms’ recovery phase this ratio quickly increases with increasing L m, which reflects an increased fraction of plasma in the total pressure balance. It is demonstrated that function L m( D st ) is derived for the main phase of storms from the equations of drift motion of RC ions in electrical and magnetic fields, reflecting the dipole character of magnetic field and scale invariance of the pattern of particle convection near the RC maximum. For the recovery phase it is obtained from the Dessler-Parker-Sckopke relationship. The obtained regularities allow one to judge about the radial profile of RC pressure from ground-based magnetic measurements (data on the D st variation).

  2. Accelerating Information Retrieval from Profile Hidden Markov Model Databases.

    Directory of Open Access Journals (Sweden)

    Ahmad Tamimi

    Full Text Available Profile Hidden Markov Model (Profile-HMM is an efficient statistical approach to represent protein families. Currently, several databases maintain valuable protein sequence information as profile-HMMs. There is an increasing interest to improve the efficiency of searching Profile-HMM databases to detect sequence-profile or profile-profile homology. However, most efforts to enhance searching efficiency have been focusing on improving the alignment algorithms. Although the performance of these algorithms is fairly acceptable, the growing size of these databases, as well as the increasing demand for using batch query searching approach, are strong motivations that call for further enhancement of information retrieval from profile-HMM databases. This work presents a heuristic method to accelerate the current profile-HMM homology searching approaches. The method works by cluster-based remodeling of the database to reduce the search space, rather than focusing on the alignment algorithms. Using different clustering techniques, 4284 TIGRFAMs profiles were clustered based on their similarities. A representative for each cluster was assigned. To enhance sensitivity, we proposed an extended step that allows overlapping among clusters. A validation benchmark of 6000 randomly selected protein sequences was used to query the clustered profiles. To evaluate the efficiency of our approach, speed and recall values were measured and compared with the sequential search approach. Using hierarchical, k-means, and connected component clustering techniques followed by the extended overlapping step, we obtained an average reduction in time of 41%, and an average recall of 96%. Our results demonstrate that representation of profile-HMMs using a clustering-based approach can significantly accelerate data retrieval from profile-HMM databases.

  3. Pre-pregnancy weight status, early pregnancy lipid profile and blood pressure course during pregnancy: The ABCD study

    NARCIS (Netherlands)

    Oostvogels, Adriëtte J. J. M.; Busschers, Wim B.; Spierings, Eline J. M.; Roseboom, Tessa J.; Gademan, Maaike G. J.; Vrijkotte, Tanja G. M.

    2017-01-01

    Although pre-pregnancy weight status and early pregnancy lipid profile are known to influence blood pressure course during pregnancy, little is known about how these two factors interact. The association between pre-pregnancy weight status and blood pressure course during pregnancy was assessed in

  4. Segregation and Clustering Effects on Complex Boron Redistribution in Strongly Doped Polycrystalline-Silicon Layers

    International Nuclear Information System (INIS)

    Abadli, S.; Mansour, F.

    2011-01-01

    This work deals with the investigation of the complex phenomenon of boron (B) transient enhanced diffusion (TED) in strongly implanted silicon (Si) layers. It concerns the instantaneous influences of the strong B concentrations, the Si layers crystallization, the clustering and the B trapping/segregation during thermal post-implantation annealing. We have used Si thin layers obtained from disilane (Si2H6) by low pressure chemical vapor deposition (LPCVD) and then B implanted with a dose of 4 x 1015 atoms/cm2 at an energy of 15 keV. To avoid long redistributions, thermal annealing was carried out at relatively low-temperatures (700, 750 and 800 'deg'C) for various short-times ranging between 1 and 30 minutes. To investigate the experimental secondary ion mass spectroscopy (SIMS) doping profiles, a redistribution model well adapted to the particular structure of Si-LPCVD layers and to the effects of strong-concentrations has been established. The good adjustment of the simulated profiles with the experimental SIMS profiles allowed a fundamental understanding about the instantaneous physical phenomena giving and disturbing the TED process in strongly doped Si-LPCVD layers. It was found that boron TED is strongly affected by the simultaneous complex kinetics of clustering, crystallization, trapping and segregation during annealing. The fast formation of small Si-B clusters enhances the B diffusivity whereas the evolution of the clusters and segregation reduce this enhancement. (author)

  5. Biochemical association of metabolic profile and microbiome in chronic pressure ulcer wounds.

    Directory of Open Access Journals (Sweden)

    Mary Cloud B Ammons

    Full Text Available Chronic, non-healing wounds contribute significantly to the suffering of patients with co-morbidities in the clinical population with mild to severely compromised immune systems. Normal wound healing proceeds through a well-described process. However, in chronic wounds this process seems to become dysregulated at the transition between resolution of inflammation and re-epithelialization. Bioburden in the form of colonizing bacteria is a major contributor to the delayed headlining in chronic wounds such as pressure ulcers. However how the microbiome influences the wound metabolic landscape is unknown. Here, we have used a Systems Biology approach to determine the biochemical associations between the taxonomic and metabolomic profiles of wounds colonized by bacteria. Pressure ulcer biopsies were harvested from primary chronic wounds and bisected into top and bottom sections prior to analysis of microbiome by pyrosequencing and analysis of metabolome using 1H nuclear magnetic resonance (NMR spectroscopy. Bacterial taxonomy revealed that wounds were colonized predominantly by three main phyla, but differed significantly at the genus level. While taxonomic profiles demonstrated significant variability between wounds, metabolic profiles shared significant similarity based on the depth of the wound biopsy. Biochemical association between taxonomy and metabolic landscape indicated significant wound-to-wound similarity in metabolite enrichment sets and metabolic pathway impacts, especially with regard to amino acid metabolism. To our knowledge, this is the first demonstration of a statistically robust correlation between bacterial colonization and metabolic landscape within the chronic wound environment.

  6. Investigation of the Unsteady Total Pressure Profile Corresponding to Counter-Rotating Vortices in an Internal Flow Application

    Science.gov (United States)

    Gordon, Kathryn; Morris, Scott; Jemcov, Aleksandar; Cameron, Joshua

    2013-11-01

    The interaction of components in a compressible, internal flow often results in unsteady interactions between the wakes and moving blades. A prime example in which this flow feature is of interest is the interaction between the downstream rotor blades in a transonic axial compressor with the wake vortices shed from the upstream inlet guide vane (IGV). Previous work shows that a double row of counter-rotating vortices convects downstream into the rotor passage as a result of the rotor blade bow shock impinging on the IGV. The rotor-relative time-mean total pressure distribution has a region of high total pressure corresponding to the pathline of the vortices. The present work focuses on the relationship between the magnitude of the time-mean rotor-relative total pressure profile and the axial spacing between the IGV and the rotor. A survey of different axial gap sizes is performed in a two-dimensional computational study to obtain the sensitivity of the pressure profile amplitude to IGV-rotor axial spacing.

  7. Background Pressure Profiles for Sonic Boom Vehicle Testing in the NASA Glenn 8- by 6-Foot Supersonic Wind Tunnel

    Science.gov (United States)

    Castner, Raymond; Shaw, Stephen; Adamson, Eric; Simerly, Stephanie

    2013-01-01

    In an effort to identify test facilities that offer sonic boom measurement capabilities, an exploratory test program was initiated using wind tunnels at NASA research centers. The subject of this report is the sonic boom pressure rail data collected in the Glenn Research Center 8- by 6-Foot Supersonic Wind Tunnel. The purpose is to summarize the lessons learned based on the test activity, specifically relating to collecting sonic boom data which has a large amount of spatial pressure variation. The wind tunnel background pressure profiles are presented as well as data which demonstrated how both wind tunnel Mach number and model support-strut position affected the wind tunnel background pressure profile. Techniques were developed to mitigate these effects and are presented.

  8. A new retrieval algorithm for tropospheric temperature, humidity and pressure profiling based on GNSS radio occultation data

    Science.gov (United States)

    Kirchengast, Gottfried; Li, Ying; Scherllin-Pirscher, Barbara; Schwärz, Marc; Schwarz, Jakob; Nielsen, Johannes K.

    2017-04-01

    The GNSS radio occultation (RO) technique is an important remote sensing technique for obtaining thermodynamic profiles of temperature, humidity, and pressure in the Earth's troposphere. However, due to refraction effects of both dry ambient air and water vapor in the troposphere, retrieval of accurate thermodynamic profiles at these lower altitudes is challenging and requires suitable background information in addition to the RO refractivity information. Here we introduce a new moist air retrieval algorithm aiming to improve the quality and robustness of retrieving temperature, humidity and pressure profiles in moist air tropospheric conditions. The new algorithm consists of four steps: (1) use of prescribed specific humidity and its uncertainty to retrieve temperature and its associated uncertainty; (2) use of prescribed temperature and its uncertainty to retrieve specific humidity and its associated uncertainty; (3) use of the previous results to estimate final temperature and specific humidity profiles through optimal estimation; (4) determination of air pressure and density profiles from the results obtained before. The new algorithm does not require elaborated matrix inversions which are otherwise widely used in 1D-Var retrieval algorithms, and it allows a transparent uncertainty propagation, whereby the uncertainties of prescribed variables are dynamically estimated accounting for their spatial and temporal variations. Estimated random uncertainties are calculated by constructing error covariance matrices from co-located ECMWF short-range forecast and corresponding analysis profiles. Systematic uncertainties are estimated by empirical modeling. The influence of regarding or disregarding vertical error correlations is quantified. The new scheme is implemented with static input uncertainty profiles in WEGC's current OPSv5.6 processing system and with full scope in WEGC's next-generation system, the Reference Occultation Processing System (rOPS). Results from

  9. Analytical calculations of the rotational transform angles in the torsatron systems with different plasma pressure profiles

    International Nuclear Information System (INIS)

    Kuznetsov, Yu.K.; Pinos, I.B.; Tyupa, V.I.

    1999-01-01

    With formulas for averaging over magnetic surfaces general analytical expressions are here deduced to determine the rotational transform angles in stellarator systems having different plasma pressure profiles

  10. Planck/SDSS Cluster Mass and Gas Scaling Relations for a Volume-Complete redMaPPer Sample

    Science.gov (United States)

    Jimeno, Pablo; Diego, Jose M.; Broadhurst, Tom; De Martino, I.; Lazkoz, Ruth

    2018-04-01

    Using Planck satellite data, we construct Sunyaev-Zel'dovich (SZ) gas pressure profiles for a large, volume-complete sample of optically selected clusters. We have defined a sample of over 8,000 redMaPPer clusters from the Sloan Digital Sky Survey (SDSS), within the volume-complete redshift region 0.100 trend towards larger break radius with increasing cluster mass. Our SZ-based masses fall ˜16% below the mass-richness relations from weak lensing, in a similar fashion as the "hydrostatic bias" related with X-ray derived masses. Finally, we derive a tight Y500-M500 relation over a wide range of cluster mass, with a power law slope equal to 1.70 ± 0.07, that agrees well with the independent slope obtained by the Planck team with an SZ-selected cluster sample, but extends to lower masses with higher precision.

  11. Effect of high hydrostatic pressure on small oxygen-related clusters in silicon: LVM studies

    International Nuclear Information System (INIS)

    Murin, L.I.; Lindstroem, J.L.; Misiuk, A.

    2003-01-01

    Local vibrational mode (LVM) spectroscopy is used to explore the effect of high hydrostatic pressure (HP) on the formation of small oxygen-related clusters (dimers, trimers, thermal donors, and C-O complexes) at 450 deg. C and 650 deg. C in Cz-Si crystals with different impurity content and prehistory. It is found, in agreement with previous studies, that HP enhances the oxygen clustering in Cz-Si at elevated temperatures. The effect of HP is related mainly to enhancement in the diffusivity of single oxygen atoms and small oxygen aggregates. HP does not noticeably increase the binding energies of the most simple oxygen related complexes like O 2i , C s O ni . The biggest HP effect on the thermal double donor (TDDs) generation is revealed in hydrogenated samples. Heat-treatment of such samples at 450 deg. C under HP results in extremely high TDD introduction rates as well as in a strong increase in the concentration of the first TDD species

  12. Profiling of secondary metabolite gene clusters regulated by LaeA in Aspergillus niger FGSC A1279 based on genome sequencing and transcriptome analysis.

    Science.gov (United States)

    Wang, Bin; Lv, Yangyong; Li, Xuejie; Lin, Yiying; Deng, Hai; Pan, Li

    The global regulator LaeA controls the production of many fungal secondary metabolites, possibly via chromatin remodeling. Here we aimed to survey the secondary metabolite profile regulated by LaeA in Aspergillus niger FGSC A1279 by genome sequencing and comparative transcriptomics between the laeA deletion (ΔlaeA) and overexpressing (OE-laeA) mutants. Genome sequencing revealed four putative polyketide synthase genes specific to FGSC A1279, suggesting that the corresponding polyketide compounds might be unique to FGSC A1279. RNA-seq data revealed 281 putative secondary metabolite genes upregulated in the OE-laeA mutants, including 22 secondary metabolite backbone genes. LC-MS chemical profiling illustrated that many secondary metabolites were produced in OE-laeA mutants compared to wild type and ΔlaeA mutants, providing potential resources for drug discovery. KEGG analysis annotated 16 secondary metabolite clusters putatively linked to metabolic pathways. Furthermore, 34 of 61 Zn 2 Cys 6 transcription factors located in secondary metabolite clusters were differentially expressed between ΔlaeA and OE-laeA mutants. Three secondary metabolite clusters (cluster 18, 30 and 33) containing Zn 2 Cys 6 transcription factors that were upregulated in OE-laeA mutants were putatively linked to KEGG pathways, suggesting that Zn 2 Cys 6 transcription factors might play an important role in synthesizing secondary metabolites regulated by LaeA. Taken together, LaeA dramatically influences the secondary metabolite profile in FGSC A1279. Copyright © 2017 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

  13. Mass Distribution in Galaxy Cluster Cores

    Energy Technology Data Exchange (ETDEWEB)

    Hogan, M. T.; McNamara, B. R.; Pulido, F.; Vantyghem, A. N. [Department of Physics and Astronomy, University of Waterloo, Waterloo, ON, N2L 3G1 (Canada); Nulsen, P. E. J. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Russell, H. R. [Institute of Astronomy, Madingley Road, Cambridge CB3 0HA (United Kingdom); Edge, A. C. [Centre for Extragalactic Astronomy, Department of Physics, Durham University, Durham DH1 3LE (United Kingdom); Main, R. A., E-mail: m4hogan@uwaterloo.ca [Canadian Institute for Theoretical Astrophysics, University of Toronto, 60 St. George Street, Toronto, ON, M5S 3H8 (Canada)

    2017-03-01

    Many processes within galaxy clusters, such as those believed to govern the onset of thermally unstable cooling and active galactic nucleus feedback, are dependent upon local dynamical timescales. However, accurate mapping of the mass distribution within individual clusters is challenging, particularly toward cluster centers where the total mass budget has substantial radially dependent contributions from the stellar ( M {sub *}), gas ( M {sub gas}), and dark matter ( M {sub DM}) components. In this paper we use a small sample of galaxy clusters with deep Chandra observations and good ancillary tracers of their gravitating mass at both large and small radii to develop a method for determining mass profiles that span a wide radial range and extend down into the central galaxy. We also consider potential observational pitfalls in understanding cooling in hot cluster atmospheres, and find tentative evidence for a relationship between the radial extent of cooling X-ray gas and nebular H α emission in cool-core clusters. At large radii the entropy profiles of our clusters agree with the baseline power law of K ∝ r {sup 1.1} expected from gravity alone. At smaller radii our entropy profiles become shallower but continue with a power law of the form K ∝ r {sup 0.67} down to our resolution limit. Among this small sample of cool-core clusters we therefore find no support for the existence of a central flat “entropy floor.”.

  14. Linear pressure profile estimation along a penstock associated with transients due to severe defects

    Science.gov (United States)

    Kueny, J. L.; Combes, G.; Lourenço, M.; Clary, V.; Ballester, J. L.

    2014-03-01

    The purpose of this article is to show how the pressure load profile along a penstock of an hydroplant and the corresponding flow rate is obtained from the pressure signal using a code called ACHYL CF. In particular the paper will present how it is possible to reconstruct the history of the incident after a strong transient state, in the case of two plants with Pelton turbines and one DSPCF device on a branch of the circuit. For plant1 the DSPCF device observes an overrun of the maximal allowed pressure after the filling of the injector branch and for plant_2, a strong transient leads to the rupture of the penstock.

  15. Linear pressure profile estimation along a penstock associated with transients due to severe defects

    International Nuclear Information System (INIS)

    Kueny, J L; Clary, V; Combes, G; Lourenço, M; Ballester, J L

    2014-01-01

    The purpose of this article is to show how the pressure load profile along a penstock of an hydroplant and the corresponding flow rate is obtained from the pressure signal using a code called ACHYL CF. In particular the paper will present how it is possible to reconstruct the history of the incident after a strong transient state, in the case of two plants with Pelton turbines and one DSPCF device on a branch of the circuit. For plant 1 the DSPCF device observes an overrun of the maximal allowed pressure after the filling of the injector branch and for plant 2 , a strong transient leads to the rupture of the penstock

  16. GASP. V. Ram-pressure stripping of a ring Hoag's-like galaxy in a massive cluster

    Science.gov (United States)

    Moretti, A.; Poggianti, B. M.; Gullieuszik, M.; Mapelli, M.; Jaffé, Y. L.; Fritz, J.; Biviano, A.; Fasano, G.; Bettoni, D.; Vulcani, B.; D'Onofrio, M.

    2018-04-01

    Through an ongoing MUSE program dedicated to study gas removal processes in galaxies (GAs Stripping Phenomena in galaxies with MUSE, GASP), we have obtained deep and wide integral field spectroscopy of the galaxy JO171. This galaxy resembles the Hoag's galaxy, one of the most spectacular examples of ring galaxies, characterized by a completely detached ring of young stars surrounding a central old spheroid. At odds with the isolated Hoag's galaxy, JO171 is part of a dense environment, the cluster Abell 3667, which is causing gas stripping along tentacles. Moreover, its ring counter-rotates with respect to the central spheroid. The joint analysis of the stellar populations and the gas/stellar kinematics shows that the origin of the ring was not due to an internal mechanism, but was related to a gas accretion event that happened in the distant past, prior to accretion on to Abell 3667, most probably within a filament. More recently, since infall in the cluster, the gas in the ring has been stripped by ram pressure, causing the quenching of star formation in the stripped half of the ring. This is the first observed case of ram-pressure stripping in action in a ring galaxy, and MUSE observations are able to reveal both of the events (accretion and stripping) that caused dramatic transformations in this galaxy.

  17. The Halo Boundary of Galaxy Clusters in the SDSS

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, Eric; Jain, Bhuvnesh; Sheth, Ravi K. [Center for Particle Cosmology, Department of Physics, University of Pennsylvania, Philadelphia, PA 19104 (United States); Chang, Chihway; Kravtsov, Andrey [Kavli Institute for Cosmological Physics, The University of Chicago, Chicago, IL 60637 (United States); Adhikari, Susmita; Dalal, Neal [Department of Astronomy, University of Illinois at Urbana-Champaign, Champaign, IL 61801 (United States); More, Surhud [Kavli Institute for the Physics and Mathematics of the Universe (WPI), Tokyo Institutes for Advanced Study, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa-shi, Chiba, 277-8583 (Japan); Rozo, Eduardo [Department of Physics, University of Arizona, Tucson, AZ 85721 (United States); Rykoff, Eli, E-mail: ebax@sas.upenn.edu [Kavli Institute for Particle Astrophysics and Cosmology, P.O. Box 2450, Stanford University, Stanford, CA 94305 (United States)

    2017-05-20

    Analytical models and simulations predict a rapid decline in the halo density profile associated with the transition from the “infalling” regime outside the halo to the “collapsed” regime within the halo. Using data from SDSS, we explore evidence for such a feature in the density profiles of galaxy clusters using several different approaches. We first estimate the steepening of the outer galaxy density profile around clusters, finding evidence for truncation of the halo profile. Next, we measure the galaxy density profile around clusters using two sets of galaxies selected on color. We find evidence of an abrupt change in galaxy colors that coincides with the location of the steepening of the density profile. Since galaxies that have completed orbits within the cluster are more likely to be quenched of star formation and thus appear redder, this abrupt change in galaxy color can be associated with the transition from single-stream to multi-stream regimes. We also use a standard model comparison approach to measure evidence for a “splashback”-like feature, but find that this approach is very sensitive to modeling assumptions. Finally, we perform measurements using an independent cluster catalog to test for potential systematic errors associated with cluster selection. We identify several avenues for future work: improved understanding of the small-scale galaxy profile, lensing measurements, identification of proxies for the halo accretion rate, and other tests. With upcoming data from the DES, KiDS, and HSC surveys, we can expect significant improvements in the study of halo boundaries.

  18. The Halo Boundary of Galaxy Clusters in the SDSS

    International Nuclear Information System (INIS)

    Baxter, Eric; Jain, Bhuvnesh; Sheth, Ravi K.; Chang, Chihway; Kravtsov, Andrey; Adhikari, Susmita; Dalal, Neal; More, Surhud; Rozo, Eduardo; Rykoff, Eli

    2017-01-01

    Analytical models and simulations predict a rapid decline in the halo density profile associated with the transition from the “infalling” regime outside the halo to the “collapsed” regime within the halo. Using data from SDSS, we explore evidence for such a feature in the density profiles of galaxy clusters using several different approaches. We first estimate the steepening of the outer galaxy density profile around clusters, finding evidence for truncation of the halo profile. Next, we measure the galaxy density profile around clusters using two sets of galaxies selected on color. We find evidence of an abrupt change in galaxy colors that coincides with the location of the steepening of the density profile. Since galaxies that have completed orbits within the cluster are more likely to be quenched of star formation and thus appear redder, this abrupt change in galaxy color can be associated with the transition from single-stream to multi-stream regimes. We also use a standard model comparison approach to measure evidence for a “splashback”-like feature, but find that this approach is very sensitive to modeling assumptions. Finally, we perform measurements using an independent cluster catalog to test for potential systematic errors associated with cluster selection. We identify several avenues for future work: improved understanding of the small-scale galaxy profile, lensing measurements, identification of proxies for the halo accretion rate, and other tests. With upcoming data from the DES, KiDS, and HSC surveys, we can expect significant improvements in the study of halo boundaries.

  19. The electron beam diagnostic of the clustered supersonic nitrogen jets

    Science.gov (United States)

    Avtaeva, S. V.; Yakovleva, T. S.; Kalyada, V. V.; Zarvin, A. E.

    2017-11-01

    Axial and radial distributions of the rotational temperature and density of N2 molecules in supersonic nitrogen jets formed with conic nozzles (critical diameters dcr of 0.17 and 0.21 mm) were studied using the electron beam fluorescence technique at stagnation pressures P0 of 0.1-0.6 MPa. A rotational temperature Tr , equaling a gas temperature Tg owing to fast RT relaxation, was obtained using the rotational line relative intensity distribution in (0-1) vibrational band of the N2 first negative system. Gas density profiles in the jets were obtained using the integral intensity of the band. It is found, Tr at the nozzle outlet is of the order of a few tens of Kelvin and at further expansion Tr drops up to 15-20K at distance of (100-200) dcr . The gas temperature and density distributions in the studied supersonic nitrogen jets are not similar to the isentropic distributions. It is shown that the lower is the stagnation pressure the faster the gas density and temperature decrease with distance from the nozzle. Increase in P0 leads to elevating Tg in the jets. A reason for this effect may be cluster formation in the jets. Estimations of cluster mean sizes in the jets using Hagena’s parameter show presence of large clusters (M≥200) at P0 = 0.4-0.6 MPa.

  20. Pressure ulcer multidisciplinary teams via telemedicine: a pragmatic cluster randomized stepped wedge trial in long term care.

    Science.gov (United States)

    Stern, Anita; Mitsakakis, Nicholas; Paulden, Mike; Alibhai, Shabbir; Wong, Josephine; Tomlinson, George; Brooker, Ann-Sylvia; Krahn, Murray; Zwarenstein, Merrick

    2014-02-24

    The study was conducted to determine the clinical and cost effectiveness of enhanced multi-disciplinary teams (EMDTs) vs. 'usual care' for the treatment of pressure ulcers in long term care (LTC) facilities in Ontario, Canada We conducted a multi-method study: a pragmatic cluster randomized stepped-wedge trial, ethnographic observation and in-depth interviews, and an economic evaluation. Long term care facilities (clusters) were randomly allocated to start dates of the intervention. An advance practice nurse (APN) with expertise in skin and wound care visited intervention facilities to educate staff on pressure ulcer prevention and treatment, supported by an off-site hospital based expert multi-disciplinary wound care team via email, telephone, or video link as needed. The primary outcome was rate of reduction in pressure ulcer surface area (cm2/day) measured on before and after standard photographs by an assessor blinded to facility allocation. Secondary outcomes were time to healing, probability of healing, pressure ulcer incidence, pressure ulcer prevalence, wound pain, hospitalization, emergency department visits, utility, and cost. 12 of 15 eligible LTC facilities were randomly selected to participate and randomized to start date of the intervention following the stepped wedge design. 137 residents with a total of 259 pressure ulcers (stage 2 or greater) were recruited over the 17 month study period. No statistically significant differences were found between control and intervention periods on any of the primary or secondary outcomes. The economic evaluation demonstrated a mean reduction in direct care costs of $650 per resident compared to 'usual care'. The qualitative study suggested that onsite support by APN wound specialists was welcomed, and is responsible for reduced costs through discontinuation of expensive non evidence based treatments. Insufficient allocation of nursing home staff time to wound care may explain the lack of impact on healing

  1. The Role of Cerenkov Radiation in the Pressure Balance of Cool Core Clusters of Galaxies

    Energy Technology Data Exchange (ETDEWEB)

    Lieu, Richard [Department of Physics, University of Alabama, Huntsville, AL 35899 (United States)

    2017-03-20

    Despite the substantial progress made recently in understanding the role of AGN feedback and associated non-thermal effects, the precise mechanism that prevents the core of some clusters of galaxies from collapsing catastrophically by radiative cooling remains unidentified. In this Letter, we demonstrate that the evolution of a cluster's cooling core, in terms of its density, temperature, and magnetic field strength, inevitably enables the plasma electrons there to quickly become Cerenkov loss dominated, with emission at the radio frequency of ≲350 Hz, and with a rate considerably exceeding free–free continuum and line emission. However, the same does not apply to the plasmas at the cluster's outskirts, which lacks such radiation. Owing to its low frequency, the radiation cannot escape, but because over the relevant scale size of a Cerenkov wavelength the energy of an electron in the gas cannot follow the Boltzmann distribution to the requisite precision to ensure reabsorption always occurs faster than stimulated emission, the emitting gas cools before it reheats. This leaves behind the radiation itself, trapped by the overlying reflective plasma, yet providing enough pressure to maintain quasi-hydrostatic equilibrium. The mass condensation then happens by Rayleigh–Taylor instability, at a rate determined by the outermost radius where Cerenkov radiation can occur. In this way, it is possible to estimate the rate at ≈2 M {sub ⊙} year{sup −1}, consistent with observational inference. Thus, the process appears to provide a natural solution to the longstanding problem of “cooling flow” in clusters; at least it offers another line of defense against cooling and collapse should gas heating by AGN feedback be inadequate in some clusters.

  2. The Atacama Cosmology Telescope: Sunyaev-Zel'dovich selected galaxy clusters at 148 GHz from three seasons of data

    Energy Technology Data Exchange (ETDEWEB)

    Hasselfield, Matthew; Hlozek, Renée [Department of Astrophysical Sciences, Peyton Hall, Princeton University, Princeton, NJ 08544 (United States); Hilton, Matt [Astrophysics and Cosmology Research Unit, School of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, Durban, 4041 (South Africa); Marriage, Tobias A.; Crichton, Devin; Gralla, Megan B. [Dept. of Physics and Astronomy, The Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218-2686 (United States); Addison, Graeme E.; Halpern, Mark [Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, V6T 1Z4 (Canada); Barrientos, L. Felipe; Dünner, Rolando [Departamento de Astronomía y Astrofísica, Facultad de Física, Pontificía Universidad Católica, Casilla 306, Santiago 22 (Chile); Battaglia, Nicholas [Department of Physics, Carnegie Mellon University, Pittsburgh, PA 15213 (United States); Battistelli, Elia S. [Department of Physics, University of Rome ' ' La Sapienza' ' , Piazzale Aldo Moro 5, I-00185 Rome (Italy); Bond, J. Richard; Hajian, Amir; Hincks, Adam D. [Canadian Institute for Theoretical Astrophysics, University of Toronto, Toronto, ON, M5S 3H8 (Canada); Das, Sudeep [High Energy Physics Division, Argonne National Laboratory, 9700 S Cass Avenue, Lemont, IL 60439 (United States); Devlin, Mark J.; Dicker, Simon R. [Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, PA 19104 (United States); Dunkley, Joanna [Department of Astrophysics, Oxford University, Oxford, OX1 3RH (United Kingdom); Fowler, Joseph W., E-mail: mhasse@astro.princeton.edu, E-mail: hiltonm@ukzn.ac.za, E-mail: marriage@pha.jhu.edu [NIST Quantum Devices Group, 325 Broadway Mailcode 817.03, Boulder, CO 80305 (United States); and others

    2013-07-01

    We present a catalog of 68 galaxy clusters, of which 19 are new discoveries, detected via the Sunyaev-Zel'dovich effect (SZ) at 148 GHz in the Atacama Cosmology Telescope (ACT) survey on the celestial equator. With this addition, the ACT collaboration has reported a total of 91 optically confirmed, SZ detected clusters. The 504 square degree survey region includes 270 square degrees of overlap with SDSS Stripe 82, permitting the confirmation of SZ cluster candidates in deep archival optical data. The subsample of 48 clusters within Stripe 82 is estimated to be 90% complete for M{sub 500c} > 4.5 × 10{sup 14}M{sub s}un and redshifts 0.15 < z < 0.8. While a full suite of matched filters is used to detect the clusters, the sample is studied further through a ''Profile Based Amplitude Analysis'' using a statistic derived from a single filter at a fixed θ{sub 500} = 5.'9 angular scale. This new approach incorporates the cluster redshift along with prior information on the cluster pressure profile to fix the relationship between the cluster characteristic size (R{sub 500}) and the integrated Compton parameter (Y{sub 500}). We adopt a one-parameter family of ''Universal Pressure Profiles'' (UPP) with associated scaling laws, derived from X-ray measurements of nearby clusters, as a baseline model. Three additional models of cluster physics are used to investigate a range of scaling relations beyond the UPP prescription. Assuming a concordance cosmology, the UPP scalings are found to be nearly identical to an adiabatic model, while a model incorporating non-thermal pressure better matches dynamical mass measurements and masses from the South Pole Telescope. A high signal to noise ratio subsample of 15 ACT clusters with complete optical follow-up is used to obtain cosmological constraints. We demonstrate, using fixed scaling relations, how the constraints depend on the assumed gas model if only SZ measurements are used, and

  3. APFIM investigation of clustering in neutron-irradiated Fe-Cu alloys and pressure vessel steels

    International Nuclear Information System (INIS)

    Auger, P.; Pareige, P.; Blavette, D.

    1996-01-01

    Pressure vessel steels used in PWRs are known to be prone to hardening and embrittlement under neutron irradiation. The changes in mechanical properties are commonly supposed to result from the formation of point defects, dislocation loops, voids and copper-rich precipitates. However, the real nature of the irradiation induced damage, in these particularly low copper steels (>0,1 wt%), has not been clearly identify yet. A new experimental work has been carried out thanks to atom probe and field ion microscopy (APFIM) facilities and, more particularly with a new generation of atom probe recently developed, namely the tomographic atom probe (TAP), in order to improve: the understanding of the complex behavior of copper precipitation which occurs when low-alloyed Fe-Cu model alloys are irradiated with neutrons; the microstructural characterization of the pressure vessel steel of the CHOOZ A reactor under various fluences (French Surveillance Programme). The investigations clearly reveal the precipitation of copper-rich clusters in irradiated Fe-Cu alloys while more complicated Si, Ni, Mn and Cu-solute 'clouds' were observed to develop in the low-copper ferritic solid solution of the pressure vessel steel. (authors)

  4. Motivational profiles of medical students: association with study effort, academic performance and exhaustion.

    Science.gov (United States)

    Kusurkar, Rashmi A; Croiset, Gerda; Galindo-Garré, Francisca; Ten Cate, Olle

    2013-06-19

    Students enter the medical study with internally generated motives like genuine interest (intrinsic motivation) and/or externally generated motives like parental pressure or desire for status or prestige (controlled motivation). According to Self-determination theory (SDT), students could differ in their study effort, academic performance and adjustment to the study depending on the endorsement of intrinsic motivation versus controlled motivation. The objectives of this study were to generate motivational profiles of medical students using combinations of high or low intrinsic and controlled motivation and test whether different motivational profiles are associated with different study outcomes. Participating students (N = 844) from University Medical Center Utrecht, the Netherlands, were classified to different subgroups through K-means cluster analysis using intrinsic and controlled motivation scores. Cluster membership was used as an independent variable to assess differences in study strategies, self-study hours, academic performance and exhaustion from study. Four clusters were obtained: High Intrinsic High Controlled (HIHC), Low Intrinsic High Controlled (LIHC), High Intrinsic Low Controlled (HILC), and Low Intrinsic Low Controlled (LILC). HIHC profile, including the students who are interest + status motivated, constituted 25.2% of the population (N = 213). HILC profile, including interest-motivated students, constituted 26.1% of the population (N = 220). LIHC profile, including status-motivated students, constituted 31.8% of the population (N = 268). LILC profile, including students who have a low-motivation and are neither interest nor status motivated, constituted 16.9% of the population (N = 143). Interest-motivated students (HILC) had significantly more deep study strategy (p motivated (LIHC) and low-motivation (LILC) students. The interest-motivated profile of medical students (HILC) is associated with good study hours, deep

  5. Profiling Local Optima in K-Means Clustering: Developing a Diagnostic Technique

    Science.gov (United States)

    Steinley, Douglas

    2006-01-01

    Using the cluster generation procedure proposed by D. Steinley and R. Henson (2005), the author investigated the performance of K-means clustering under the following scenarios: (a) different probabilities of cluster overlap; (b) different types of cluster overlap; (c) varying samples sizes, clusters, and dimensions; (d) different multivariate…

  6. SHARAKU: an algorithm for aligning and clustering read mapping profiles of deep sequencing in non-coding RNA processing.

    Science.gov (United States)

    Tsuchiya, Mariko; Amano, Kojiro; Abe, Masaya; Seki, Misato; Hase, Sumitaka; Sato, Kengo; Sakakibara, Yasubumi

    2016-06-15

    Deep sequencing of the transcripts of regulatory non-coding RNA generates footprints of post-transcriptional processes. After obtaining sequence reads, the short reads are mapped to a reference genome, and specific mapping patterns can be detected called read mapping profiles, which are distinct from random non-functional degradation patterns. These patterns reflect the maturation processes that lead to the production of shorter RNA sequences. Recent next-generation sequencing studies have revealed not only the typical maturation process of miRNAs but also the various processing mechanisms of small RNAs derived from tRNAs and snoRNAs. We developed an algorithm termed SHARAKU to align two read mapping profiles of next-generation sequencing outputs for non-coding RNAs. In contrast with previous work, SHARAKU incorporates the primary and secondary sequence structures into an alignment of read mapping profiles to allow for the detection of common processing patterns. Using a benchmark simulated dataset, SHARAKU exhibited superior performance to previous methods for correctly clustering the read mapping profiles with respect to 5'-end processing and 3'-end processing from degradation patterns and in detecting similar processing patterns in deriving the shorter RNAs. Further, using experimental data of small RNA sequencing for the common marmoset brain, SHARAKU succeeded in identifying the significant clusters of read mapping profiles for similar processing patterns of small derived RNA families expressed in the brain. The source code of our program SHARAKU is available at http://www.dna.bio.keio.ac.jp/sharaku/, and the simulated dataset used in this work is available at the same link. Accession code: The sequence data from the whole RNA transcripts in the hippocampus of the left brain used in this work is available from the DNA DataBank of Japan (DDBJ) Sequence Read Archive (DRA) under the accession number DRA004502. yasu@bio.keio.ac.jp Supplementary data are available

  7. The Atacama Cosmology Telescope: Dynamical Masses for 44 SZ-Selected Galaxy Clusters over 755 Square Degrees

    Science.gov (United States)

    Sifon, Cristobal; Battaglia, Nick; Hasselfield, Matthew; Menanteau, Felipe; Barrientos, L. Felipe; Bond, J. Richard; Crichton, Devin; Devlin, Mark J.; Dunner, Rolando; Hilton, Matt; hide

    2016-01-01

    We present galaxy velocity dispersions and dynamical mass estimates for 44 galaxy clusters selected via the Sunyaev-Zeldovich (SZ) effect by the Atacama Cosmology Telescope. Dynamical masses for 18 clusters are reported here for the first time. Using N-body simulations, we model the different observing strategies used to measure the velocity dispersions and account for systematic effects resulting from these strategies. We find that the galaxy velocity distributions may be treated as isotropic, and that an aperture correction of up to 7 per cent in the velocity dispersion is required if the spectroscopic galaxy sample is sufficiently concentrated towards the cluster centre. Accounting for the radial profile of the velocity dispersion in simulations enables consistent dynamical mass estimates regardless of the observing strategy. Cluster masses M200 are in the range (1 - 15) times 10 (sup 14) Solar Masses. Comparing with masses estimated from the SZ distortion assuming a gas pressure profile derived from X-ray observations gives a mean SZ-to-dynamical mass ratio of 1:10 plus or minus 0:13, but there is an additional 0.14 systematic uncertainty due to the unknown velocity bias; the statistical uncertainty is dominated by the scatter in the mass-velocity dispersion scaling relation. This ratio is consistent with previous determinations at these mass scales.

  8. Star Cluster Structure from Hierarchical Star Formation

    Science.gov (United States)

    Grudic, Michael; Hopkins, Philip; Murray, Norman; Lamberts, Astrid; Guszejnov, David; Schmitz, Denise; Boylan-Kolchin, Michael

    2018-01-01

    Young massive star clusters (YMCs) spanning 104-108 M⊙ in mass generally have similar radial surface density profiles, with an outer power-law index typically between -2 and -3. This similarity suggests that they are shaped by scale-free physics at formation. Recent multi-physics MHD simulations of YMC formation have also produced populations of YMCs with this type of surface density profile, allowing us to narrow down the physics necessary to form a YMC with properties as observed. We show that the shallow density profiles of YMCs are a natural result of phase-space mixing that occurs as they assemble from the clumpy, hierarchically-clustered configuration imprinted by the star formation process. We develop physical intuition for this process via analytic arguments and collisionless N-body experiments, elucidating the connection between star formation physics and star cluster structure. This has implications for the early-time structure and evolution of proto-globular clusters, and prospects for simulating their formation in the FIRE cosmological zoom-in simulations.

  9. Structural profiles of human miRNA families from pairwise clustering

    DEFF Research Database (Denmark)

    Kaczkowski, Bogumil; Þórarinsson, Elfar; Reiche, Kristin

    2009-01-01

    secondary structure already predicted, little is known about the patterns of structural conservation among pre-miRNAs. We address this issue by clustering the human pre-miRNA sequences based on pairwise, sequence and secondary structure alignment using FOLDALIGN, followed by global multiple alignment...... of obtained clusters by WAR. As a result, the common secondary structure was successfully determined for four FOLDALIGN clusters: the RF00027 structural family of the Rfam database and three clusters with previously undescribed consensus structures. Availability: http://genome.ku.dk/resources/mirclust...

  10. Evaluating Mixture Modeling for Clustering: Recommendations and Cautions

    Science.gov (United States)

    Steinley, Douglas; Brusco, Michael J.

    2011-01-01

    This article provides a large-scale investigation into several of the properties of mixture-model clustering techniques (also referred to as latent class cluster analysis, latent profile analysis, model-based clustering, probabilistic clustering, Bayesian classification, unsupervised learning, and finite mixture models; see Vermunt & Magdison,…

  11. The cost-effectiveness of a patient centred pressure ulcer prevention care bundle: Findings from the INTACT cluster randomised trial.

    Science.gov (United States)

    Whitty, Jennifer A; McInnes, Elizabeth; Bucknall, Tracey; Webster, Joan; Gillespie, Brigid M; Banks, Merrilyn; Thalib, Lukman; Wallis, Marianne; Cumsille, Jose; Roberts, Shelley; Chaboyer, Wendy

    2017-10-01

    Pressure ulcers are serious, avoidable, costly and common adverse outcomes of healthcare. To evaluate the cost-effectiveness of a patient-centred pressure ulcer prevention care bundle compared to standard care. Cost-effectiveness and cost-benefit analyses of pressure ulcer prevention performed from the health system perspective using data collected alongside a cluster-randomised trial. Eight tertiary hospitals in Australia. Adult patients receiving either a patient-centred pressure ulcer prevention care bundle (n=799) or standard care (n=799). Direct costs related to the intervention and preventative strategies were collected from trial data and supplemented by micro-costing data on patient turning and skin care from a 4-week substudy (n=317). The time horizon for the economic evaluation matched the trial duration, with the endpoint being diagnosis of a new pressure ulcer, hospital discharge/transfer or 28days; whichever occurred first. For the cost-effectiveness analysis, the primary outcome was the incremental costs of prevention per additional hospital acquired pressure ulcer case avoided, estimated using a two-stage cluster-adjusted non-parametric bootstrap method. The cost-benefit analysis estimated net monetary benefit, which considered both the costs of prevention and any difference in length of stay. All costs are reported in AU$(2015). The care bundle cost AU$144.91 (95%CI: $74.96 to $246.08) more per patient than standard care. The largest contributors to cost were clinical nurse time for repositioning and skin inspection. In the cost-effectiveness analysis, the care bundle was estimated to cost an additional $3296 (95%CI: dominant to $144,525) per pressure ulcer avoided. This estimate is highly uncertain. Length of stay was unexpectedly higher in the care bundle group. In a cost-benefit analysis which considered length of stay, the net monetary benefit for the care bundle was estimated to be -$2320 (95%CI -$3900, -$1175) per patient, suggesting the care

  12. Cluster Physics with Merging Galaxy Clusters

    Directory of Open Access Journals (Sweden)

    Sandor M. Molnar

    2016-02-01

    Full Text Available Collisions between galaxy clusters provide a unique opportunity to study matter in a parameter space which cannot be explored in our laboratories on Earth. In the standard LCDM model, where the total density is dominated by the cosmological constant ($Lambda$ and the matter density by cold dark matter (CDM, structure formation is hierarchical, and clusters grow mostly by merging.Mergers of two massive clusters are the most energetic events in the universe after the Big Bang,hence they provide a unique laboratory to study cluster physics.The two main mass components in clusters behave differently during collisions:the dark matter is nearly collisionless, responding only to gravity, while the gas is subject to pressure forces and dissipation, and shocks and turbulenceare developed during collisions. In the present contribution we review the different methods used to derive the physical properties of merging clusters. Different physical processes leave their signatures on different wavelengths, thusour review is based on a multifrequency analysis. In principle, the best way to analyze multifrequency observations of merging clustersis to model them using N-body/HYDRO numerical simulations. We discuss the results of such detailed analyses.New high spatial and spectral resolution ground and space based telescopeswill come online in the near future. Motivated by these new opportunities,we briefly discuss methods which will be feasible in the near future in studying merging clusters.

  13. INTroducing A Care bundle To prevent pressure injury (INTACT) in at-risk patients: A protocol for a cluster randomised trial.

    Science.gov (United States)

    Chaboyer, Wendy; Bucknall, Tracey; Webster, Joan; McInnes, Elizabeth; Banks, Merrilyn; Wallis, Marianne; Gillespie, Brigid M; Whitty, Jennifer A; Thalib, Lukman; Roberts, Shelley; Cullum, Nicky

    2015-11-01

    Pressure injuries are a significant clinical and economic issue, affecting both patients and the health care system. Many pressure injuries in hospitals are facility acquired, and are largely preventable. Despite growing evidence and directives for pressure injury prevention, implementation of preventative strategies is suboptimal, and pressure injuries remain a serious problem in hospitals. This study will test the effectiveness and cost-effectiveness of a patient-centred pressure injury prevention care bundle on the development of hospital acquired pressure injury in at-risk patients. This is a multi-site, parallel group cluster randomised trial. The hospital is the unit of randomisation. Adult medical and surgical patients admitted to the study wards of eight hospitals who are (a) deemed to be at risk of pressure injury (i.e. have reduced mobility), (b) expected to stay in hospital for ≥48h, (c) admitted to hospital in the past 36h; and (d) able to provide informed consent will be eligible to participate. Consenting patients will receive either the pressure injury prevention care bundle or standard care. The care bundle contains three main messages: (1) keep moving; (2) look after your skin; and (3) eat a healthy diet. Nurses will receive education about the intervention. Patients will exit the study upon development of a pressure injury, hospital discharge or 28 days, whichever comes first; transfer to another hospital or transfer to critical care and mechanically ventilated. The primary outcome is incidence of hospital acquired pressure injury. Secondary outcomes are pressure injury stage, patient participation in care and health care costs. A health economic sub-study and a process evaluation will be undertaken alongside the trial. Data will be analysed at the cluster (hospital) and patient level. Estimates of hospital acquired pressure injury incidence in each group, group differences and 95% confidence interval and p values will be reported. To our

  14. Cluster analysis

    OpenAIRE

    Mucha, Hans-Joachim; Sofyan, Hizir

    2000-01-01

    As an explorative technique, duster analysis provides a description or a reduction in the dimension of the data. It classifies a set of observations into two or more mutually exclusive unknown groups based on combinations of many variables. Its aim is to construct groups in such a way that the profiles of objects in the same groups are relatively homogenous whereas the profiles of objects in different groups are relatively heterogeneous. Clustering is distinct from classification techniques, ...

  15. LoCuSS: THE MASS DENSITY PROFILE OF MASSIVE GALAXY CLUSTERS AT z = 0.2 {sup ,}

    Energy Technology Data Exchange (ETDEWEB)

    Okabe, Nobuhiro; Umetsu, Keiichi [Academia Sinica Institute of Astronomy and Astrophysics (ASIAA), P. O. Box 23-141, Taipei 10617, Taiwan (China); Smith, Graham P. [School of Physics and Astronomy, University of Birmingham, Edgbaston, Birmingham B15 2TT (United Kingdom); Takada, Masahiro [Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU, WPI), University of Tokyo, Chiba 277-8582 (Japan); Futamase, Toshifumi, E-mail: okabe@asiaa.sinica.edu.tw, E-mail: gps@star.sr.bham.ac.uk [Astronomical Institute, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578 (Japan)

    2013-06-01

    We present a stacked weak-lensing analysis of an approximately mass-selected sample of 50 galaxy clusters at 0.15 < z < 0.3, based on observations with Suprime-Cam on the Subaru Telescope. We develop a new method for selecting lensed background galaxies from which we estimate that our sample of red background galaxies suffers just 1% contamination. We detect the stacked tangential shear signal from the full sample of 50 clusters, based on this red sample of background galaxies, at a total signal-to-noise ratio of 32.7. The Navarro-Frenk-White model is an excellent fit to the data, yielding sub-10% statistical precision on mass and concentration: M{sub vir}=7.19{sup +0.53}{sub -0.50} Multiplication-Sign 10{sup 14} h{sup -1} M{sub sun}, c{sub vir}=5.41{sup +0.49}{sub -0.45} (c{sub 200}=4.22{sup +0.40}{sub -0.36}). Tests of a range of possible systematic errors, including shear calibration and stacking-related issues, indicate that they are subdominant to the statistical errors. The concentration parameter obtained from stacking our approximately mass-selected cluster sample is broadly in line with theoretical predictions. Moreover, the uncertainty on our measurement is comparable with the differences between the different predictions in the literature. Overall, our results highlight the potential for stacked weak-lensing methods to probe the mean mass density profile of cluster-scale dark matter halos with upcoming surveys, including Hyper-Suprime-Cam, Dark Energy Survey, and KIDS.

  16. Effect of primordial non-Gaussianities on galaxy clusters scaling relations

    Science.gov (United States)

    Trindade, A. M. M.; da Silva, Antonio

    2017-07-01

    Galaxy clusters are a valuable source of cosmological information. Their formation and evolution depends on the underlying cosmology and on the statistical nature of the primordial density fluctuations. Here we investigate the impact of primordial non-Gaussianities (PNG) on the scaling properties of galaxy clusters. We performed a series of hydrodynamic N-body simulations featuring adiabatic gas physics and different levels of non-Gaussianity within the Λ cold dark matter framework. We focus on the T-M, S-M, Y-M and YX-M scalings relating the total cluster mass with temperature, entropy and Sunyaev-Zeld'ovich integrated pressure that reflect the thermodynamic state of the intracluster medium. Our results show that PNG have an impact on cluster scalings laws. The scalings mass power-law indexes are almost unaffected by the existence of PNG, but the amplitude and redshift evolution of their normalizations are clearly affected. Changes in the Y-M and YX-M normalizations are as high as 22 per cent and 16 per cent when fNL varies from -500 to 500, respectively. Results are consistent with the view that positive/negative fNL affect cluster profiles due to an increase/decrease of cluster concentrations. At low values of fNL, as suggested by present Planck constraints on a scale invariant fNL, the impact on the scaling normalizations is only a few per cent. However, if fNL varies with scale, PNG may have larger amplitudes at clusters scales; thus, our results suggest that PNG should be taken into account when cluster data are used to infer or forecast cosmological parameters from existing or future cluster surveys.

  17. THE GEMINI/HST CLUSTER PROJECT: STRUCTURAL AND PHOTOMETRIC PROPERTIES OF GALAXIES IN THREE z = 0.28-0.89 CLUSTERS

    International Nuclear Information System (INIS)

    Chiboucas, Kristin; Joergensen, Inger; Barr, Jordi; Collobert, Maela; Davies, Roger; Flint, Kathleen

    2009-01-01

    We present the data processing and analysis techniques we are using to determine the structural and photometric properties of galaxies in our Gemini/HST Galaxy Cluster Project sample. The goal of this study is to understand cluster galaxy evolution in terms of scaling relations and structural properties of cluster galaxies at redshifts 0.15 1/4 law and Sersic function two-dimensional surface brightness profiles to each of the galaxies in our sample. Using simulated galaxies, we test how the assumed profile affects the derived parameters and how the uncertainties affect our Fundamental Plane results. We find that while fitting galaxies that have Sersic index n 1/4 law profiles systematically overestimates the galaxy radius and flux, the combination of profile parameters that enter the Fundamental Plane has uncertainties that are small. Average systematic offsets and associated random uncertainties in magnitude and log r e for n>2 galaxies fitted with r 1/4 law profiles are -0.1 ± 0.3 and 0.1 ± 0.2, respectively. The combination of effective radius and surface brightness, log r e - βlog (I) e , that enters the Fundamental Plane produces offsets smaller than -0.02 ± 0.10. This systematic error is insignificant and independent of galaxy magnitude or size. A catalog of photometry and surface brightness profile parameters is presented for three of the clusters in our sample, RX J0142.0+2131, RX J0152.7-1357, and RX J1226.9+3332 at redshifts 0.28, 0.83, and 0.89, respectively.

  18. Sunlight Modulates Fruit Metabolic Profile and Shapes the Spatial Pattern of Compound Accumulation within the Grape Cluster.

    Science.gov (United States)

    Reshef, Noam; Walbaum, Natasha; Agam, Nurit; Fait, Aaron

    2017-01-01

    Vineyards are characterized by their large spatial variability of solar irradiance (SI) and temperature, known to effectively modulate grape metabolism. To explore the role of sunlight in shaping fruit composition and cluster uniformity, we studied the spatial pattern of incoming irradiance, fruit temperature and metabolic profile within individual grape clusters under three levels of sunlight exposure. The experiment was conducted in a vineyard of Cabernet Sauvignon cv. located in the Negev Highlands, Israel, where excess SI and midday temperatures are known to degrade grape quality. Filtering SI lowered the surface temperature of exposed fruits and increased the uniformity of irradiance and temperature in the cluster zone. SI affected the overall levels and patterns of accumulation of sugars, organic acids, amino acids and phenylpropanoids, across the grape cluster. Increased exposure to sunlight was associated with lower accumulation levels of malate, aspartate, and maleate but with higher levels of valine, leucine, and serine, in addition to the stress-related proline and GABA. Flavan-3-ols metabolites showed a negative response to SI, whereas flavonols were highly induced. The overall levels of anthocyanins decreased with increased sunlight exposure; however, a hierarchical cluster analysis revealed that the members of this family were grouped into three distinct accumulation patterns, with malvidin anthocyanins and cyanidin-glucoside showing contrasting trends. The flavonol-glucosides, quercetin and kaempferol, exhibited a logarithmic response to SI, leading to improved cluster uniformity under high-light conditions. Comparing the within-cluster variability of metabolite accumulation highlighted the stability of sugars, flavan-3-ols, and cinnamic acid metabolites to SI, in contrast to the plasticity of flavonols. A correlation-based network analysis revealed that extended exposure to SI modified metabolic coordination, increasing the number of negative

  19. Microstructural characterization of atom clusters in irradiated pressure vessel steels and model alloys

    International Nuclear Information System (INIS)

    Auger, P.; Pareige, P.; Akamatsu, M.; Van Duysen, J.C.

    1993-01-01

    In order to characterize the microstructural evolution of iron solid solution under irradiation, two pressure vessel steels irradiated in service conditions, and, for comparison, low copper model alloys irradiated with neutrons and electrons, have been studied through small angle neutron scattering and atom probe experiments. In Fe-Cu model alloys, copper clusters are formed containing uncertain proportions of iron. In the low copper industrial steels, the feature is more complex; solute atoms such as Ni, Mn and Si, sometimes associated with Cu, segregate as ''clouds'' more or less condensed in the iron solid solution. These silicides, or at least Si, Ni, Mn association, may facilitate the copper segregation although the initial iron matrix contains a low copper concentration. (authors). 24 refs., 3 figs., 2 tabs

  20. Microstructural characterization of atom clusters in irradiated pressure vessel steels and model alloys

    Energy Technology Data Exchange (ETDEWEB)

    Auger, P; Pareige, P [Rouen Univ., 76 - Mont-Saint-Aignan (France); Akamatsu, M; Van Duysen, J C [Electricite de France (EDF), 77 - Ecuelles (France)

    1994-12-31

    In order to characterize the microstructural evolution of iron solid solution under irradiation, two pressure vessel steels irradiated in service conditions, and, for comparison, low copper model alloys irradiated with neutrons and electrons, have been studied through small angle neutron scattering and atom probe experiments. In Fe-Cu model alloys, copper clusters are formed containing uncertain proportions of iron. In the low copper industrial steels, the feature is more complex; solute atoms such as Ni, Mn and Si, sometimes associated with Cu, segregate as ``clouds`` more or less condensed in the iron solid solution. These silicides, or at least Si, Ni, Mn association, may facilitate the copper segregation although the initial iron matrix contains a low copper concentration. (authors). 24 refs., 3 figs., 2 tabs.

  1. OMERACT-based fibromyalgia symptom subgroups: an exploratory cluster analysis.

    Science.gov (United States)

    Vincent, Ann; Hoskin, Tanya L; Whipple, Mary O; Clauw, Daniel J; Barton, Debra L; Benzo, Roberto P; Williams, David A

    2014-10-16

    The aim of this study was to identify subsets of patients with fibromyalgia with similar symptom profiles using the Outcome Measures in Rheumatology (OMERACT) core symptom domains. Female patients with a diagnosis of fibromyalgia and currently meeting fibromyalgia research survey criteria completed the Brief Pain Inventory, the 30-item Profile of Mood States, the Medical Outcomes Sleep Scale, the Multidimensional Fatigue Inventory, the Multiple Ability Self-Report Questionnaire, the Fibromyalgia Impact Questionnaire-Revised (FIQ-R) and the Short Form-36 between 1 June 2011 and 31 October 2011. Hierarchical agglomerative clustering was used to identify subgroups of patients with similar symptom profiles. To validate the results from this sample, hierarchical agglomerative clustering was repeated in an external sample of female patients with fibromyalgia with similar inclusion criteria. A total of 581 females with a mean age of 55.1 (range, 20.1 to 90.2) years were included. A four-cluster solution best fit the data, and each clustering variable differed significantly (P FIQ-R total scores (P = 0.0004)). In our study, we incorporated core OMERACT symptom domains, which allowed for clustering based on a comprehensive symptom profile. Although our exploratory cluster solution needs confirmation in a longitudinal study, this approach could provide a rationale to support the study of individualized clinical evaluation and intervention.

  2. Measuring the stellar luminosity function and spatial density profile of the inner 0.5 pc of the Milky Way nuclear star cluster

    Science.gov (United States)

    Do, Tuan; Ghez, Andrea; Lu, Jessica R.; Morris, Mark R.; Yelda, Sylvana; Martinez, Gregory D.; Peter, Annika H. G.; Wright, Shelley; Bullock, James; Kaplinghat, Manoj; Matthews, K.

    2012-07-01

    We report on measurements of the luminosity function of early (young) and late-type (old) stars in the central 0.5 pc of the Milky Way nuclear star cluster as well as the density profiles of both components. The young (~ 6 Myr) and old stars (> 1 Gyr) in this region provide different physical probes of the environment around a supermassive black hole; the luminosity function of the young stars offers us a way to measure the initial mass function from star formation in an extreme environment, while the density profile of the old stars offers us a probe of the dynamical interaction of a star cluster with a massive black hole. The two stellar populations are separated through a near-infrared spectroscopic survey using the integral-field spectrograph OSIRIS on Keck II behind the laser guide star adaptive optics system. This spectroscopic survey is able to separate early-type (young) and late-type (old) stars with a completeness of 50% at K' = 15.5. We describe our method of completeness correction using a combination of star planting simulations and Bayesian inference. The completeness corrected luminosity function of the early-type stars contains significantly more young stars at faint magnitudes compared to previous surveys with similar depth. In addition, by using proper motion and radial velocity measurements along with anisotropic spherical Jeans modeling of the cluster, it is possible to measure the spatial density profile of the old stars, which has been difficult to constrain with number counts alone. The most probable model shows that the spatial density profile, n(r) propto r-γ, to be shallow with γ = 0.4 ± 0.2, which is much flatter than the dynamically relaxed case of γ = 3/2 to 7/4, but does rule out a 'hole' in the distribution of old stars. We show, for the first time, that the spatial density profile, the black hole mass, and velocity anisotropy can be fit simultaneously to obtain a black hole mass that is consistent with that derived from

  3. Core or Cusps: The Central Dark Matter Profile of a Strong Lensing Cluster with a Bright Central Image at Redshift 1

    Energy Technology Data Exchange (ETDEWEB)

    Collett, Thomas E.; Buckley-Geer, Elizabeth; Lin, Huan; Bacon, David; Nichol, Robert C.; Nord, Brian; Morice-Atkinson, Xan; Amara, Adam; Birrer, Simon; Kuropatkin, Nikolay; More, Anupreeta; Papovich, Casey; Romer, Kathy K.; Tessore, Nicolas; Abbott, Tim M. C.; Allam, Sahar; Annis, James; Benoit-Lévy, Aurlien; Brooks, David; Burke, David L.; Carrasco Kind, Matias; Castander, Francisco Javier J.; D’Andrea, Chris B.; da Costa, Luiz N.; Desai, Shantanu; Diehl, H. Thomas; Doel, Peter; Eifler, Tim F.; Flaugher, Brenna; Frieman, Josh; Gerdes, David W.; Goldstein, Daniel A.; Gruen, Daniel; Gschwend, Julia; Gutierrez, Gaston; James, David J.; Kuehn, Kyler; Kuhlmann, Steve; Lahav, Ofer; Li, Ting S.; Lima, Marcos; Maia, Marcio A. G.; March, Marisa; Marshall, Jennifer L.; Martini, Paul; Melchior, Peter; Miquel, Ramon; Plazas, Andrs A.; Rykoff, Eli S.; Sanchez, Eusebio; Scarpine, Vic; Schindler, Rafe; Schubnell, Michael; Sevilla-Noarbe, Ignacio; Smith, Mathew; Sobreira, Flavia; Suchyta, Eric; Swanson, Molly E. C.; Tarle, Gregory; Tucker, Douglas L.; Walker, Alistair R.

    2017-07-10

    We report on SPT-CLJ2011-5228, a giant system of arcs created by a cluster at $z=1.06$. The arc system is notable for the presence of a bright central image. The source is a Lyman Break galaxy at $z_s=2.39$ and the mass enclosed within the 14 arc second radius Einstein ring is $10^{14.2}$ solar masses. We perform a full light profile reconstruction of the lensed images to precisely infer the parameters of the mass distribution. The brightness of the central image demands that the central total density profile of the lens be shallow. By fitting the dark matter as a generalized Navarro-Frenk-White profile---with a free parameter for the inner density slope---we find that the break radius is $270^{+48}_{-76}$ kpc, and that the inner density falls with radius to the power $-0.38\\pm0.04$ at 68 percent confidence. Such a shallow profile is in strong tension with our understanding of relaxed cold dark matter halos; dark matter only simulations predict the inner density should fall as $r^{-1}$. The tension can be alleviated if this cluster is in fact a merger; a two halo model can also reconstruct the data, with both clumps (density going as $r^{-0.8}$ and $r^{-1.0}$) much more consistent with predictions from dark matter only simulations. At the resolution of our Dark Energy Survey imaging, we are unable to choose between these two models, but we make predictions for forthcoming Hubble Space Telescope imaging that will decisively distinguish between them.

  4. Economic information from Smart Meter: Nexus Between Demand Profile and Electricity Retail Price Between Demand Profile and Electricity Retail Price

    OpenAIRE

    Yu, Yang; Liu, Guangyi; Zhu, Wendong; Wang, Fei; Shu, Bin; Zhang, Kai; Rajagopal, Ram; Astier, Nicolas

    2016-01-01

    In this paper, we demonstrate that a consumer's marginal system impact is only determined by their demand profile rather than their demand level. Demand profile clustering is identical to cluster consumers according to their marginal impacts on system costs. A profile-based uniform-rate price is economically efficient as real-time pricing. We develop a criteria system to evaluate the economic efficiency of an implemented retail price scheme in a distribution system by comparing profile cluste...

  5. Electronic structure computation and differential capacitance profile in δ-doped FET as a function of hydrostatic pressure

    Energy Technology Data Exchange (ETDEWEB)

    Carlos-Pinedo, C.; Rodríguez-Vargas, I.; Martínez-Orozco, J. C. [Unidad Académica de Física. Universidad Autónoma de Zacatecas. Calzada Solidaridad Esquina con Paseo la Bufa S/N. C.P. 98060, Zacatecas, Zac. (Mexico)

    2014-05-15

    In this work we present the results obtained from the calculation of the level structure of a n-type delta-doped well Field Effect Transistor when is subjected to hydrostatic pressure. We study the energy level structure as a function of hydrostatic pressure within the range of 0 to 6 kbar for different Schottky barrier height (SBH). We use an analytical expression for the effect of hydrostatic pressure on the SBH and the pressure dependence of the basic parameters of the system as the effective mass m(P) and the dielectric constant ε(P) of GaAs. We found that due to the effects of hydrostatic pressure, in addition to electronic level structure alteration, the profile of the differential capacitance per unit area C{sup −2} is affected.

  6. Electronic structure computation and differential capacitance profile in δ-doped FET as a function of hydrostatic pressure

    International Nuclear Information System (INIS)

    Carlos-Pinedo, C.; Rodríguez-Vargas, I.; Martínez-Orozco, J. C.

    2014-01-01

    In this work we present the results obtained from the calculation of the level structure of a n-type delta-doped well Field Effect Transistor when is subjected to hydrostatic pressure. We study the energy level structure as a function of hydrostatic pressure within the range of 0 to 6 kbar for different Schottky barrier height (SBH). We use an analytical expression for the effect of hydrostatic pressure on the SBH and the pressure dependence of the basic parameters of the system as the effective mass m(P) and the dielectric constant ε(P) of GaAs. We found that due to the effects of hydrostatic pressure, in addition to electronic level structure alteration, the profile of the differential capacitance per unit area C −2 is affected

  7. Stick–slip behavior identified in helium cluster growth in the subsurface of tungsten: effects of cluster depth

    International Nuclear Information System (INIS)

    Wang, Jinlong; Niu, Liang-Liang; Shu, Xiaolin; Zhang, Ying

    2015-01-01

    We have performed a molecular dynamics study on the growth of helium (He) clusters in the subsurface of tungsten (W) (1 0 0) at 300 K, focusing on the role of cluster depth. Irregular ‘stick–slip’ behavior exhibited during the evolution of the He cluster growth is identified, which is due to the combined effects of the continuous cluster growth and the loop punching induced pressure relief. We demonstrate that the He cluster grows via trap-mutation and loop punching mechanisms. Initially, the self-interstitial atom SIA clusters are almost always attached to the He cluster; while they are instantly emitted to the surface once a critical cluster pressure is reached. The repetition of this process results in the He cluster approaching the surface via a ‘stop-and-go’ manner and the formation of surface adatom islands (surface roughening), ultimately leading to cluster bursting and He escape. We reveal that, for the Nth loop punching event, the critical size of the He cluster to trigger loop punching and the size of the emitted SIA clusters are correspondingly increased with the increasing initial cluster depth. We tentatively attribute the observed depth effects to the lower formation energies of Frenkel pairs and the greatly reduced barriers for loop punching in the stress field of the W subsurface. In addition, some intriguing features emerge, such as the morphological transformation of the He cluster from ‘platelet-like’ to spherical, to ellipsoidal with a ‘bullet-like’ tip, and finally to a ‘bottle-like’ shape after cluster rupture. (paper)

  8. MMPI profiles of males accused of severe crimes: a cluster analysis

    NARCIS (Netherlands)

    Spaans, M.; Barendregt, M.; Muller, E.; Beurs, E. de; Nijman, H.L.I.; Rinne, T.

    2009-01-01

    In studies attempting to classify criminal offenders by cluster analysis of Minnesota Multiphasic Personality Inventory-2 (MMPI-2) data, the number of clusters found varied between 10 (the Megargee System) and two (one cluster indicating no psychopathology and one exhibiting serious

  9. Sample size estimation to substantiate freedom from disease for clustered binary data with a specific risk profile

    DEFF Research Database (Denmark)

    Kostoulas, P.; Nielsen, Søren Saxmose; Browne, W. J.

    2013-01-01

    and power when applied to these groups. We propose the use of the variance partition coefficient (VPC), which measures the clustering of infection/disease for individuals with a common risk profile. Sample size estimates are obtained separately for those groups that exhibit markedly different heterogeneity......, thus, optimizing resource allocation. A VPC-based predictive simulation method for sample size estimation to substantiate freedom from disease is presented. To illustrate the benefits of the proposed approach we give two examples with the analysis of data from a risk factor study on Mycobacterium avium...

  10. The Atacama Cosmology Telescope: Sunyaev-Zel'dovich selected galaxy clusters at 148 GHz from three seasons of data

    International Nuclear Information System (INIS)

    Hasselfield, Matthew; Hlozek, Renée; Hilton, Matt; Marriage, Tobias A.; Crichton, Devin; Gralla, Megan B.; Addison, Graeme E.; Halpern, Mark; Barrientos, L. Felipe; Dünner, Rolando; Battaglia, Nicholas; Battistelli, Elia S.; Bond, J. Richard; Hajian, Amir; Hincks, Adam D.; Das, Sudeep; Devlin, Mark J.; Dicker, Simon R.; Dunkley, Joanna; Fowler, Joseph W.

    2013-01-01

    We present a catalog of 68 galaxy clusters, of which 19 are new discoveries, detected via the Sunyaev-Zel'dovich effect (SZ) at 148 GHz in the Atacama Cosmology Telescope (ACT) survey on the celestial equator. With this addition, the ACT collaboration has reported a total of 91 optically confirmed, SZ detected clusters. The 504 square degree survey region includes 270 square degrees of overlap with SDSS Stripe 82, permitting the confirmation of SZ cluster candidates in deep archival optical data. The subsample of 48 clusters within Stripe 82 is estimated to be 90% complete for M 500c > 4.5 × 10 14 M s un and redshifts 0.15 500 = 5.'9 angular scale. This new approach incorporates the cluster redshift along with prior information on the cluster pressure profile to fix the relationship between the cluster characteristic size (R 500 ) and the integrated Compton parameter (Y 500 ). We adopt a one-parameter family of ''Universal Pressure Profiles'' (UPP) with associated scaling laws, derived from X-ray measurements of nearby clusters, as a baseline model. Three additional models of cluster physics are used to investigate a range of scaling relations beyond the UPP prescription. Assuming a concordance cosmology, the UPP scalings are found to be nearly identical to an adiabatic model, while a model incorporating non-thermal pressure better matches dynamical mass measurements and masses from the South Pole Telescope. A high signal to noise ratio subsample of 15 ACT clusters with complete optical follow-up is used to obtain cosmological constraints. We demonstrate, using fixed scaling relations, how the constraints depend on the assumed gas model if only SZ measurements are used, and show that constraints from SZ data are limited by uncertainty in the scaling relation parameters rather than sample size or measurement uncertainty. We next add in seven clusters from the ACT Southern survey, including their dynamical mass measurements, which are based on galaxy velocity

  11. Ballooning mode stability for self-consistent pressure and current profiles at the H-mode edge

    International Nuclear Information System (INIS)

    Miller, R.L.; Lin-Liu, Y.R.; Osborne, T.H.; Taylor, T.S.

    1997-11-01

    The edge pressure gradient (H-mode pedestal) for computed equilibria in which the current density profile is consistent with the bootstrap current may not be limited by the first regime ballooning limit. The transition to second stability is easier for: higher elongation, intermediate triangularity, larger ratio, pedestal at larger radius, narrower pedestal width, higher q 95 , and lower collisionality

  12. The national psychological/personality profile of Romanians: An in depth analysis of the regional national psychological/personality profile of Romanians

    Directory of Open Access Journals (Sweden)

    David, D.

    2015-12-01

    Full Text Available In this article we perform an in depth analysis of the national psychological/personality profile of Romanians. Following recent developments in the field (see Rentfrow et al., 2013; 2015, we study the regional national psychological/personality profile of Romanians, based on the Big Five model (i.e., NEO PI/R. Using a representative sample (N1 = 1000, we performed a cluster analysis and identified two bipolar personality profiles in the population: cluster 1, called “Factor X-”, characterized by high neuroticism and low levels of extraversion, openness, agreeableness, and conscientiousness, and cluster 2, called “Factor X+”, characterized by the opposite configuration in personality traits, low neuroticism and high levels of extraversion, openness, agreeableness, and conscientiousness. The same two cluster pattern/solution emerged in other samples (N = 2200, with other Big Five-based instruments, and by using various methods of data (e.g., direct vs. reversed item score, controlling for item desirability and cluster (i.e., with and without “running means” analyses. These two profiles are quite evenly distributed in the overall population, but also across all geographical regions. Moreover, comparing the distribution of the five personality traits, we found just few small differences between the eight geographical divisions that we used for our analysis. These results suggest that the regional national psychological/personality profile of Romania is quite homogenous. Directions for harnessing the potential of both personality profiles are presented to the reader. Other implications based on the bipolar and fractal structure of the personality profile are discussed from an interdisciplinary perspective.

  13. Note: Interpolation for evaluation of a two-dimensional spatial profile of plasma densities at low gas pressures

    International Nuclear Information System (INIS)

    Oh, Se-Jin; Kim, Young-Chul; Chung, Chin-Wook

    2011-01-01

    An interpolation algorithm for the evaluation of the spatial profile of plasma densities in a cylindrical reactor was developed for low gas pressures. The algorithm is based on a collisionless two-dimensional fluid model. Contrary to the collisional case, i.e., diffusion fluid model, the fitting algorithm depends on the aspect ratio of the cylindrical reactor. The spatial density profile of the collisionless fitting algorithm is presented in two-dimensional images and compared with the results of the diffusion fluid model.

  14. Spatial distribution of ion energy related on electron density in a plasma channel generated in gas clusters by a femtosecond laser

    International Nuclear Information System (INIS)

    Nam, S. M.; Han, J. M.; Cha, Y. H.; Lee, Y. W.; Rhee, Y. J.; Cha, H. K.

    2008-01-01

    Neutron generation through Coulomb explosion of deuterium contained gas clusters is known as one of the very effective methods to produce fusion neutrons using a table top terawatt laser. The energy of ions produced through Coulomb explosions is very important factor to generate neutrons efficiently. Until the ion energy reaches around∼MeV level, the D D fusion reaction probability increases exponentially. The understanding of laser beam propagation and laser energy deposition in clusters is very important to improve neutron yields. As the laser beam propagates through clusters medium, laser energy is absorbed in clusters by ionization of molecules consisting clusters. When the backing pressure of gas increases, the average size of clusters increases and which results in higher energy absorption and earlier termination of laser propagation. We first installed a Michelson interferometer to view laser beam traces in a cluster plume and to measure spatial electron density profiles of a plasma channel which was produced by a laser beam. And then we measured the energy of ions distributed along the plasma channel with a translating slit to select ions from narrow parts of a plasma channel. In our experiments, methane gas was used to produce gas clusters at a room temperature and the energy distribution of proton ions for different gas backing pressure were measured by the time of flight method using dual micro channel plates. By comparing the distribution of ion energies and electron densities, we could understand the condition for effective laser energy delivery to clusters

  15. Development of a cluster-jet target for PANDA

    International Nuclear Information System (INIS)

    Gruber, A.; Marton, J.; Widmann, E.; Zmeskal, J.; PANDA Cluster Jet Target Group

    2006-01-01

    Full text: The Stefan Meyer Institute (SMI) is part of the international PANDA collaboration. The universal detector will be constructed for the future high-energy antiproton storage ring HESR at FAIR (Facility for Antiproton and Ion Research, GSI/Darmstadt). PANDA will use antiproton beams (1.5 to 15 GeV/c) for hadron physics in the charmonium region. The physics program of PANDA will comprehend charmonium spectroscopy below and above open charm threshold, search for exotics (glueballs, hybrids), lambda and double-lambda hypernuclei studies and the investigation of in-medium modifications of charmed mesons - an experimentally unexplored field. SMI contributes to major parts of the PANDA detector like the hydrogen cluster-jet target and the antiproton - cluster jet interaction zone: in order to reach the desired target density, an optimization of the nozzle and the skimmer arrangement is essential. A density-profile monitor for the cluster-jet was designed and built at SMI. Several nozzle types have been studied using different gases, temperatures and inlet pressures. To ensure low background the residual gas load in the interaction zone has to be minimized. The installation of NEG (non-evaporative-getter) coated beam pipes is planned. A prototype of the interaction zone has been set up at SMI. The pumping capacity of NEG and the reactivation cycles were tested. The status of the development of the cluster-jet target and studies of the interaction region will be presented (author)

  16. Micron-size hydrogen cluster target for laser-driven proton acceleration

    Science.gov (United States)

    Jinno, S.; Kanasaki, M.; Uno, M.; Matsui, R.; Uesaka, M.; Kishimoto, Y.; Fukuda, Y.

    2018-04-01

    As a new laser-driven ion acceleration technique, we proposed a way to produce impurity-free, highly reproducible, and robust proton beams exceeding 100 MeV using a Coulomb explosion of micron-size hydrogen clusters. In this study, micron-size hydrogen clusters were generated by expanding the cooled high-pressure hydrogen gas into a vacuum via a conical nozzle connected to a solenoid valve cooled by a mechanical cryostat. The size distributions of the hydrogen clusters were evaluated by measuring the angular distribution of laser light scattered from the clusters. The data were analyzed mathematically based on the Mie scattering theory combined with the Tikhonov regularization method. The maximum size of the hydrogen cluster at 25 K and 6 MPa in the stagnation state was recognized to be 2.15 ± 0.10 μm. The mean cluster size decreased with increasing temperature, and was found to be much larger than that given by Hagena’s formula. This discrepancy suggests that the micron-size hydrogen clusters were formed by the atomization (spallation) of the liquid or supercritical fluid phase of hydrogen. In addition, the density profiles of the gas phase were evaluated for 25 to 80 K at 6 MPa using a Nomarski interferometer. Based on the measurement results and the equation of state for hydrogen, the cluster mass fraction was obtained. 3D particles-in-cell (PIC) simulations concerning the interaction processes of micron-size hydrogen clusters with high power laser pulses predicted the generation of protons exceeding 100 MeV and accelerating in a laser propagation direction via an anisotropic Coulomb explosion mechanism, thus demonstrating a future candidate in laser-driven proton sources for upcoming multi-petawatt lasers.

  17. On the atomic line profiles in high pressure plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Janssen, J. F. J.; Gnybida, M.; Rijke, A. J.; Dijk, J. van [Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven (Netherlands); Suijker, J. L. G. [Philips Lighting R and D Category Professional Lamps, P.O. Box 80020, 5600 JM Eindhoven (Netherlands)

    2013-11-14

    In a previous contribution to this journal [H. P. Stormberg, J. Appl. Phys. 51(4), 1963 (1980)], Stormberg presented an analytical expression for the convolution of Lorentz and Levy line profiles, which models atomic radiative transitions in high pressure plasmas. Unfortunately, the derivations are flawed with errors and the final expression, while correct, is accompanied by misguiding comments about the meaning of the symbols used therein, in particular the “complex error function.” In this paper, we discuss the broadening mechanisms that give rise to Stormberg's model and present a correct derivation of his final result. We will also provide an alternative expression, based on the Faddeeva function, which has decisive computational advantages and emphasizes the real-valuedness of the result. The MATLAB/Octave scripts of our implementation have been made available on the publisher's website for future reference.

  18. Do satellite galaxies trace matter in galaxy clusters?

    Science.gov (United States)

    Wang, Chunxiang; Li, Ran; Gao, Liang; Shan, Huanyuan; Kneib, Jean-Paul; Wang, Wenting; Chen, Gang; Makler, Martin; Pereira, Maria E. S.; Wang, Lin; Maia, Marcio A. G.; Erben, Thomas

    2018-04-01

    The spatial distribution of satellite galaxies encodes rich information of the structure and assembly history of galaxy clusters. In this paper, we select a red-sequence Matched-filter Probabilistic Percolation cluster sample in SDSS Stripe 82 region with 0.1 ≤ z ≤ 0.33, 20 0.7. Using the high-quality weak lensing data from CS82 Survey, we constrain the mass profile of this sample. Then we compare directly the mass density profile with the satellite number density profile. We find that the total mass and number density profiles have the same shape, both well fitted by an NFW profile. The scale radii agree with each other within a 1σ error (r_s,gal=0.34_{-0.03}^{+0.04} Mpc versus r_s=0.37_{-0.10}^{+0.15} Mpc).

  19. A nonparametric Bayesian approach for clustering bisulfate-based DNA methylation profiles.

    Science.gov (United States)

    Zhang, Lin; Meng, Jia; Liu, Hui; Huang, Yufei

    2012-01-01

    DNA methylation occurs in the context of a CpG dinucleotide. It is an important epigenetic modification, which can be inherited through cell division. The two major types of methylation include hypomethylation and hypermethylation. Unique methylation patterns have been shown to exist in diseases including various types of cancer. DNA methylation analysis promises to become a powerful tool in cancer diagnosis, treatment and prognostication. Large-scale methylation arrays are now available for studying methylation genome-wide. The Illumina methylation platform simultaneously measures cytosine methylation at more than 1500 CpG sites associated with over 800 cancer-related genes. Cluster analysis is often used to identify DNA methylation subgroups for prognosis and diagnosis. However, due to the unique non-Gaussian characteristics, traditional clustering methods may not be appropriate for DNA and methylation data, and the determination of optimal cluster number is still problematic. A Dirichlet process beta mixture model (DPBMM) is proposed that models the DNA methylation expressions as an infinite number of beta mixture distribution. The model allows automatic learning of the relevant parameters such as the cluster mixing proportion, the parameters of beta distribution for each cluster, and especially the number of potential clusters. Since the model is high dimensional and analytically intractable, we proposed a Gibbs sampling "no-gaps" solution for computing the posterior distributions, hence the estimates of the parameters. The proposed algorithm was tested on simulated data as well as methylation data from 55 Glioblastoma multiform (GBM) brain tissue samples. To reduce the computational burden due to the high data dimensionality, a dimension reduction method is adopted. The two GBM clusters yielded by DPBMM are based on data of different number of loci (P-value < 0.1), while hierarchical clustering cannot yield statistically significant clusters.

  20. CROSS-CORRELATION WEAK LENSING OF SDSS GALAXY CLUSTERS. I. MEASUREMENTS

    International Nuclear Information System (INIS)

    Sheldon, Erin S.; Johnston, David E.; Scranton, Ryan; Koester, Benjamin P.; Oyaizu, Hiroaki; Cunha, Carlos; Lima, Marcos; Frieman, Joshua A.; McKay, Timothy A.; Lin Huan; Annis, James; Wechsler, Risa H.; Mandelbaum, Rachel; Bahcall, Neta A.; Fukugita, Masataka

    2009-01-01

    This is the first in a series of papers on the weak lensing effect caused by clusters of galaxies in Sloan Digital Sky Survey. The photometrically selected cluster sample, known as MaxBCG, includes ∼130,000 objects between redshift 0.1 and 0.3, ranging in size from small groups to massive clusters. We split the clusters into bins of richness and luminosity and stack the surface density contrast to produce mean radial profiles. The mean profiles are detected over a range of scales, from the inner halo (25 kpc h -1 ) well into the surrounding large-scale structure (30 Mpc h -1 ), with a significance of 15 to 20 in each bin. The signal over this large range of scales is best interpreted in terms of the cluster-mass cross-correlation function. We pay careful attention to sources of systematic error, correcting for them where possible. The resulting signals are calibrated to the ∼10% level, with the dominant remaining uncertainty being the redshift distribution of the background sources. We find that the profiles scale strongly with richness and luminosity. We find that the signal within a given richness bin depends upon luminosity, suggesting that luminosity is more closely correlated with mass than galaxy counts. We split the samples by redshift but detect no significant evolution. The profiles are not well described by power laws. In a subsequent series of papers, we invert the profiles to three-dimensional mass profiles, show that they are well fit by a halo model description, measure mass-to-light ratios, and provide a cosmological interpretation.

  1. Cardiovascular Risk Factors in Cluster Headache.

    Science.gov (United States)

    Lasaosa, S Santos; Diago, E Bellosta; Calzada, J Navarro; Benito, A Velázquez

    2017-06-01

     Patients with cluster headache tend to have a dysregulation of systemic blood pressure such as increased blood pressure variability and decreased nocturnal dipping. This pattern of nocturnal nondipping is associated with end-organ damage and increased risk of cardiovascular disease.  To determine if cluster headache is associated with a higher risk of cardiovascular disease.  Cross-sectional study of 33 cluster headache patients without evidence of cardiovascular disease and 30 age- and gender-matched healthy controls. Ambulatory blood pressure monitoring was performed in all subjects. We evaluate anthropometric, hematologic, and structural parameters (carotid intima-media thickness and ankle-brachial index).  Of the 33 cluster headache patients, 16 (48.5%) were nondippers, a higher percentage than expected. Most of the cluster headache patients (69.7%) also presented a pathological ankle-brachial index. In terms of the carotid intima-media thickness values, 58.3% of the patients were in the 75th percentile, 25% were in the 90th percentile, and 20% were in the 95th percentile. In the control group, only five of the 30 subjects (16.7%) had a nondipper pattern ( P  =   0.004), with 4.54% in the 90th and 95th percentiles ( P  =   0.012 and 0.015).  Compared with healthy controls, patients with cluster headache presented a high incidence (48.5%) of nondipper pattern, pathological ankle-brachial index (69.7%), and intima-media thickness values above the 75th percentile. These findings support the hypothesis that patients with cluster headache present increased risk of cardiovascular disease. © 2016 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  2. MASSIVE CLUSTERS IN THE INNER REGIONS OF NGC 1365: CLUSTER FORMATION AND GAS DYNAMICS IN GALACTIC BARS

    International Nuclear Information System (INIS)

    Elmegreen, Bruce G.; Galliano, Emmanuel; Alloin, Danielle

    2009-01-01

    Cluster formation and gas dynamics in the central regions of barred galaxies are not well understood. This paper reviews the environment of three 10 7 M sun clusters near the inner Lindblad resonance (ILR) of the barred spiral NGC 1365. The morphology, mass, and flow of H I and CO gas in the spiral and barred regions are examined for evidence of the location and mechanism of cluster formation. The accretion rate is compared with the star formation rate to infer the lifetime of the starburst. The gas appears to move from inside corotation in the spiral region to looping filaments in the interbar region at a rate of ∼6 M sun yr -1 before impacting the bar dustlane somewhere along its length. The gas in this dustlane moves inward, growing in flux as a result of the accretion to ∼40 M sun yr -1 near the ILR. This inner rate exceeds the current nuclear star formation rate by a factor of 4, suggesting continued buildup of nuclear mass for another ∼0.5 Gyr. The bar may be only 1-2 Gyr old. Extrapolating the bar flow back in time, we infer that the clusters formed in the bar dustlane outside the central dust ring at a position where an interbar filament currently impacts the lane. The ram pressure from this impact is comparable to the pressure in the bar dustlane, and both are comparable to the pressure in the massive clusters. Impact triggering is suggested. The isothermal assumption in numerical simulations seems inappropriate for the rarefaction parts of spiral and bar gas flows. The clusters have enough lower-mass counterparts to suggest they are part of a normal power-law mass distribution. Gas trapping in the most massive clusters could explain their [Ne II] emission, which is not evident from the lower-mass clusters nearby.

  3. Effects of oxygen addition in reactive cluster beam deposition of tungsten by magnetron sputtering with gas aggregation

    Energy Technology Data Exchange (ETDEWEB)

    Polášek, J., E-mail: xpolasekj@seznam.cz [Department of Surface and Plasma Science, Faculty of Mathematics and Physic, Charles University, V Holešovičkách 2, Prague 8, CZ-18000 (Czech Republic); Mašek, K. [Department of Surface and Plasma Science, Faculty of Mathematics and Physic, Charles University, V Holešovičkách 2, Prague 8, CZ-18000 (Czech Republic); Marek, A.; Vyskočil, J. [HVM Plasma Ltd., Na Hutmance 2, Prague 5, CZ-158 00 (Czech Republic)

    2015-09-30

    In this work, we investigated the possibilities of tungsten and tungsten oxide nanoclusters generation by means of non-reactive and reactive magnetron sputtering with gas aggregation. It was found that in pure argon atmosphere, cluster aggregation proceeded in two regimes depending on argon pressure in the aggregation chamber. At the lower pressure, cluster generation was dominated by two-body collisions yielding larger clusters (about 5.5 nm in diameter) at lower rate. At higher pressures, cluster generation was dominated by three-body collisions yielding smaller clusters (3–4 nm in diameter) at higher rate. The small amount of oxygen admixture in the aggregation chamber had considerable influence on cluster aggregation process. At certain critical pressure, the presence of oxygen led to the raise of deposition rate and cluster size. Resulting clusters were composed mostly of tungsten trioxide. The oxygen pressure higher than critical led to the target poisoning and the decrease in the sputtering rate. Critical oxygen pressure decreased with increasing argon pressure, suggesting that cluster aggregation process was influenced by atomic oxygen species (namely, O{sup −} ion) generated by oxygen–argon collisions in the magnetron plasma. - Highlights: • Formation of tungsten and tungsten oxide clusters was observed. • Two modes of cluster aggregation in pure argon atmosphere were found. • Dependence of cluster deposition speed and size on oxygen admixture was observed. • Changes of dependence on oxygen with changing argon pressure were described.

  4. Effects of oxygen addition in reactive cluster beam deposition of tungsten by magnetron sputtering with gas aggregation

    International Nuclear Information System (INIS)

    Polášek, J.; Mašek, K.; Marek, A.; Vyskočil, J.

    2015-01-01

    In this work, we investigated the possibilities of tungsten and tungsten oxide nanoclusters generation by means of non-reactive and reactive magnetron sputtering with gas aggregation. It was found that in pure argon atmosphere, cluster aggregation proceeded in two regimes depending on argon pressure in the aggregation chamber. At the lower pressure, cluster generation was dominated by two-body collisions yielding larger clusters (about 5.5 nm in diameter) at lower rate. At higher pressures, cluster generation was dominated by three-body collisions yielding smaller clusters (3–4 nm in diameter) at higher rate. The small amount of oxygen admixture in the aggregation chamber had considerable influence on cluster aggregation process. At certain critical pressure, the presence of oxygen led to the raise of deposition rate and cluster size. Resulting clusters were composed mostly of tungsten trioxide. The oxygen pressure higher than critical led to the target poisoning and the decrease in the sputtering rate. Critical oxygen pressure decreased with increasing argon pressure, suggesting that cluster aggregation process was influenced by atomic oxygen species (namely, O"− ion) generated by oxygen–argon collisions in the magnetron plasma. - Highlights: • Formation of tungsten and tungsten oxide clusters was observed. • Two modes of cluster aggregation in pure argon atmosphere were found. • Dependence of cluster deposition speed and size on oxygen admixture was observed. • Changes of dependence on oxygen with changing argon pressure were described.

  5. Weak-lensing mass calibration of the Atacama Cosmology Telescope equatorial Sunyaev-Zeldovich cluster sample with the Canada-France-Hawaii telescope stripe 82 survey

    Energy Technology Data Exchange (ETDEWEB)

    Battaglia, N.; Miyatake, H.; Hasselfield, M.; Calabrese, E.; Ferrara, S.; Hložek, R. [Dept. of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Leauthaud, A. [Kavli IPMU (WPI), UTIAS, The University of Tokyo, Kashiwa, Chiba 277-8583 (Japan); Gralla, M.B.; Crichton, D. [Dept. of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States); Allison, R.; Dunkley, J. [Dept. of Astrophysics, University of Oxford, Oxford OX1 3RH (United Kingdom); Bond, J.R. [Canadian Institute for Theoretical Astrophysics, Toronto, ON M5S 3H8 (Canada); Devlin, M.J. [Dept. of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104 (United States); Dünner, R. [Dept. de Astronomía y Astrofísica, Facultad de Física, Pontificia Universidad Católica de Chile, Santiago (Chile); Erben, T. [Argelander-Institut für Astronomie, University of Bonn, 53121 Bonn (Germany); Halpern, M.; Hincks, A.D. [Dept. of Physics and Astronomy, University of British Columbia, Vancouver, BC, V6T 1Z4 (Canada); Hilton, M. [Astrophysics and Cosmology Research Unit, School of Mathematical, Statistics and Computer Science, University of KwaZulu-Natal, Durban, 4041 (South Africa); Hill, J.C. [Dept. of Astronomy, Columbia University, New York, NY 10027 (United States); Huffenberger, K.M., E-mail: nbatta@astro.princeton.edu [Dept. of Physics, Florida State University, Tallahassee, FL 32306 (United States); and others

    2016-08-01

    Mass calibration uncertainty is the largest systematic effect for using clusters of galaxies to constrain cosmological parameters. We present weak lensing mass measurements from the Canada-France-Hawaii Telescope Stripe 82 Survey for galaxy clusters selected through their high signal-to-noise thermal Sunyaev-Zeldovich (tSZ) signal measured with the Atacama Cosmology Telescope (ACT). For a sample of 9 ACT clusters with a tSZ signal-to-noise greater than five the average weak lensing mass is (4.8±0.8) ×10{sup 14} M{sub ⊙}, consistent with the tSZ mass estimate of (4.70±1.0) ×10{sup 14} M{sub ⊙} which assumes a universal pressure profile for the cluster gas. Our results are consistent with previous weak-lensing measurements of tSZ-detected clusters from the Planck satellite. When comparing our results, we estimate the Eddington bias correction for the sample intersection of Planck and weak-lensing clusters which was previously excluded.

  6. Weak-lensing mass calibration of the Atacama Cosmology Telescope equatorial Sunyaev-Zeldovich cluster sample with the Canada-France-Hawaii telescope stripe 82 survey

    International Nuclear Information System (INIS)

    Battaglia, N.; Miyatake, H.; Hasselfield, M.; Calabrese, E.; Ferrara, S.; Hložek, R.; Leauthaud, A.; Gralla, M.B.; Crichton, D.; Allison, R.; Dunkley, J.; Bond, J.R.; Devlin, M.J.; Dünner, R.; Erben, T.; Halpern, M.; Hincks, A.D.; Hilton, M.; Hill, J.C.; Huffenberger, K.M.

    2016-01-01

    Mass calibration uncertainty is the largest systematic effect for using clusters of galaxies to constrain cosmological parameters. We present weak lensing mass measurements from the Canada-France-Hawaii Telescope Stripe 82 Survey for galaxy clusters selected through their high signal-to-noise thermal Sunyaev-Zeldovich (tSZ) signal measured with the Atacama Cosmology Telescope (ACT). For a sample of 9 ACT clusters with a tSZ signal-to-noise greater than five the average weak lensing mass is (4.8±0.8) ×10 14 M ⊙ , consistent with the tSZ mass estimate of (4.70±1.0) ×10 14 M ⊙ which assumes a universal pressure profile for the cluster gas. Our results are consistent with previous weak-lensing measurements of tSZ-detected clusters from the Planck satellite. When comparing our results, we estimate the Eddington bias correction for the sample intersection of Planck and weak-lensing clusters which was previously excluded.

  7. XPS investigation of monatomic and cluster argon ion sputtering of tantalum pentoxide

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Robin, E-mail: r.simpson@surrey.ac.uk [The Surface Analysis Laboratory, Department of Mechanical Engineering Sciences, University of Surrey (United Kingdom); Thermo Scientific, East Grinstead (United Kingdom); White, Richard G. [Thermo Scientific, East Grinstead (United Kingdom); Watts, John F.; Baker, Mark A. [The Surface Analysis Laboratory, Department of Mechanical Engineering Sciences, University of Surrey (United Kingdom)

    2017-05-31

    Highlights: • Ion beam induced oxide reduction from monatomic and gas cluster ion beam exposure are compared. • Lower relative level of preferential sputtering is shown in gas cluster ion beam depth profiling. • A lack of “steady state” is observed in gas cluster ion beam depth profiles of tantalum pentoxide. • Possible mechanisms behind the observed results, including temperature effects are proposed. - Abstract: In recent years, gas cluster ion beams (GCIB) have become the cutting edge of ion beam technology to sputter etch organic materials in surface analysis. However, little is currently known on the ability of argon cluster ions (Ar{sub n}{sup +}) to etch metal oxides and other technologically important inorganic compounds and no depth profiles have previously been reported. In this work, XPS depth profiles through a certified (European standard BCR-261T) 30 nm thick Ta{sub 2}O{sub 5} layer grown on Ta foil using monatomic Ar{sup +} and Ar{sub 1000}{sup +} cluster ions have been performed at different incident energies. The preferential sputtering of oxygen induced using 6 keV Ar{sub 1000}{sup +} ions is lower relative to 3 keV and 500 eV Ar{sup +} ions. Ar{sup +} ions exhibit a steady state O/Ta ratio through the bulk oxide but Ar{sub 1000}{sup +} ions show a gradual decrease in the O/Ta ratio as a function of depth. The depth resolution and etch rate is substantially better for the monatomic beam compared to the cluster beam. Higher O concentrations are observed when the underlying Ta bulk metal is sputtered for the Ar{sub 1000}{sup +} profiles compared to the Ar{sup +} profiles.

  8. Pre-attack signs and symptoms in cluster headache: Characteristics and time profile.

    Science.gov (United States)

    Snoer, Agneta; Lund, Nunu; Beske, Rasmus; Jensen, Rigmor; Barloese, Mads

    2018-05-01

    Introduction In contrast to the premonitory phase of migraine, little is known about the pre-attack (prodromal) phase of a cluster headache. We aimed to describe the nature, prevalence, and duration of pre-attack symptoms in cluster headache. Methods Eighty patients with episodic cluster headache or chronic cluster headache, according to ICHD-3 beta criteria, were invited to participate. In this observational study, patients underwent a semi-structured interview where they were asked about the presence of 31 symptoms/signs in relation to a typical cluster headache attack. Symptoms included previously reported cluster headache pre-attack symptoms, premonitory migraine symptoms and accompanying symptoms of migraine and cluster headache. Results Pre-attack symptoms were reported by 83.3% of patients, with an average of 4.25 (SD 3.9) per patient. Local and painful symptoms, occurring with a median of 10 minutes before attack, were reported by 70%. Local and painless symptoms and signs, occurring with a median of 10 minutes before attack, were reported by 43.8% and general symptoms, occurring with a median of 20 minutes before attack, were reported by 62.5% of patients. Apart from a dull/aching sensation in the attack area being significantly ( p cluster headache. Since the origin of cluster headache attacks is still unresolved, studies of pre-attack symptoms could contribute to the understanding of cluster headache pathophysiology. Furthermore, identification and recognition of pre-attack symptoms could potentially allow earlier abortive treatment.

  9. Absorption of femtosecond laser pulses by atomic clusters

    International Nuclear Information System (INIS)

    Lin Jingquan; Zhang Jie; Li Yingjun; Chen Liming; Lu Tiezheng; Teng Hao

    2001-01-01

    Energy absorption by Xe, Ar, He atomic clusters are investigated using laser pulses with 5 mJ energy in 150 fs duration. Experimental results show that the size of cluster and laser absorption efficiency are strongly dependent on several factors, such as the working pressure of pulse valve, atomic number Z of the gas. Absorption fraction of Xe clusters is as high as 45% at a laser intensity of 1 x 10 15 W/cm 2 with 20 x 10 5 Pa gas jet backing pressure. Absorption of the atomic clusters is greatly reduced by introducing pre-pulses. Ion energy measurements confirm that the efficient energy deposition results in a plasma with very high ion temperature

  10. A Method for Recording Urethral Pressure Profiles in Female Rats.

    Directory of Open Access Journals (Sweden)

    Shengfei Xu

    Full Text Available Urethral pressure profile (UPP and leak-point pressure (LPP measurements as well as external urethral sphincter (EUS electromyography (EMG and videourodynamic analyses are the primary methods for evaluating urethral function in humans. However, UPP recording in female rats, a widely used animal model, is challenging due to their small body sizes. This study reports a novel method for recording UPP in female rats.Seventeen anesthetized female rats were studied. LPP data for 14 rats were included. The other 3 rats were excluded because of death or abnormal urogenital organs. UPP curves were recorded using a modified water-perfusion catheter system, with the lateral hole facing the 3-, 6-, 9-, and 12-o'clock positions in a randomized sequence. LPP, functional urethral length (FUL and maximum urethral closure pressure (MUCP were analyzed.The mean LPP was 64.39 ± 20.29 cm H2O. The mean FUL and MUCP values at the 3-, 6-, 9-, and 12-o'clock positions were 12.90 ± 1.20, 16.70 ± 1.95, 13.90 ± 2.42, and 11.60 ± 0.97 mm, respectively, and 38.70 ± 11.85, 33.90 ± 11.82, 37.40 ± 11.95, and 71.90 ± 23.01 cm H2O, respectively. The FUL at the 6-o'clock position and MUCP at the 12-o'clock position were significantly greater than those at the other 3 positions. The FUL and MUCP of repeated UPP recordings were not significantly different than those of the first recordings.UPP recording using a modified method based on a water-perfusion catheter system is feasible and replicable in female rats. It produces UPP curves that sensitively and appreciably reflect detailed pressure changes at different points within the urethra and thus provides opportunity to evaluate urethral structures, especially the urethral sphincter, in detail. These results may enhance the utility of female rat models in research of urinary sphincter mechanisms.

  11. A theoretical study of water equilibria: the cluster distribution versus temperature and pressure for (H2O)n, n = 1-60, and ice.

    Science.gov (United States)

    Lenz, Annika; Ojamäe, Lars

    2009-10-07

    The size distribution of water clusters at equilibrium is studied using quantum-chemical calculations in combination with statistical thermodynamics. The necessary energetic data is obtained by quantum-chemical B3LYP computations and through extrapolations from the B3LYP results for the larger clusters. Clusters with up to 60 molecules are included in the equilibrium computations. Populations of different cluster sizes are calculated using both an ideal gas model with noninteracting clusters and a model where a correction for the interaction energy is included analogous to the van der Waals law. In standard vapor the majority of the water molecules are monomers. For the ideal gas model at 1 atm large clusters [56-mer (0-120 K) and 28-mer (100-260 K)] dominate at low temperatures and separate to smaller clusters [21-22-mer (170-280 K) and 4-6-mer (270-320 K) and to monomers (300-350 K)] when the temperature is increased. At lower pressure the transition from clusters to monomers lies at lower temperatures and fewer cluster sizes are formed. The computed size distribution exhibits enhanced peaks for the clusters consisting of 21 and 28 water molecules; these sizes are for protonated water clusters often referred to as magic numbers. If cluster-cluster interactions are included in the model the transition from clusters to monomers is sharper (i.e., occurs over a smaller temperature interval) than when the ideal-gas model is used. Clusters with 20-22 molecules dominate in the liquid region. When a large icelike cluster is included it will dominate for temperatures up to 325 K for the noninteracting clusters model. Thermodynamic properties (C(p), DeltaH) were calculated with in general good agreement with experimental values for the solid and gas phase. A formula for the number of H-bond topologies in a given cluster structure is derived. For the 20-mer it is shown that the number of topologies contributes to making the population of dodecahedron-shaped cluster larger

  12. Comparing effects of perfusion and hydrostatic pressure on gene profiles of human chondrocyte.

    Science.gov (United States)

    Zhu, Ge; Mayer-Wagner, Susanne; Schröder, Christian; Woiczinski, Matthias; Blum, Helmut; Lavagi, Ilaria; Krebs, Stefan; Redeker, Julia I; Hölzer, Andreas; Jansson, Volkmar; Betz, Oliver; Müller, Peter E

    2015-09-20

    Hydrostatic pressure and perfusion have been shown to regulate the chondrogenic potential of articular chondrocytes. In order to compare the effects of hydrostatic pressure plus perfusion (HPP) and perfusion (P) we investigated the complete gene expression profiles of human chondrocytes under HPP and P. A simplified bioreactor was constructed to apply loading (0.1 MPa for 2 h) and perfusion (2 ml) through the same piping by pressurizing the medium directly. High-density monolayer cultures of human chondrocytes were exposed to HPP or P for 4 days. Controls (C) were maintained in static cultures. Gene expression was evaluated by sequencing (RNAseq) and quantitative real-time PCR analysis. Both treatments changed gene expression levels of human chondrocytes significantly. Specifically, HPP and P increased COL2A1 expression and decreased COL1A1 and MMP-13 expression. Despite of these similarities, RNAseq revealed a list of cartilage genes including ACAN, ITGA10 and TNC, which were differentially expressed by HPP and P. Of these candidates, adhesion related molecules were found to be upregulated in HPP. Both HPP and P treatment had beneficial effects on chondrocyte differentiation and decreased catabolic enzyme expression. The study provides new insight into how hydrostatic pressure and perfusion enhance cartilage differentiation and inhibit catabolic effects. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Temperament clusters associate with anxiety disorder comorbidity in depression.

    Science.gov (United States)

    Paavonen, Vesa; Luoto, Kaisa; Lassila, Antero; Leinonen, Esa; Kampman, Olli

    2018-08-15

    Individual temperament is associated with psychiatric morbidity and could explain differences in psychiatric comorbidities. We investigated the association of temperament profile clusters with anxiety disorder comorbidity in patients with depression. We assessed the temperament of 204 specialized care-treated depressed patients with the Temperament and Character Inventory (TCI-R) and their diagnoses with the Mini International Neuropsychiatric Interview. Two-step cluster analysis was used for defining patients' temperament profiles and logistic regression analysis was used for predicting different anxiety disorders for various temperament profiles. Four temperament clusters were found: 1) Novelty seekers with highest Novelty Seeking scores (n = 56),2) Persistent with highest Persistence scores (n = 36), 3) Reserved with lowest Novelty Seeking scores (n = 66) and 4) Wearied with highest Harm avoidance, lowest Reward Dependence and lowest Persistence scores (n = 58). After adjusting for clinical variables, panic disorder and/or agoraphobia were predicted by Novelty seekers' temperament profile with odds ratio [OR] = 3.5 (95% confidence interval [CI] = 1.8 - 6.9, p < 0.001), social anxiety disorder was predicted by Wearied temperament profile with OR = 3.4 (95% CI = 1.6 - 7.5, p = 0.002), and generalized anxiety disorder was predicted by Reserved temperament profile with OR = 2.6 (95% CI = 1.2 - 5.3, p = 0.01). The patients' temperament profiles were assessed while displaying depressive symptoms, which may have affected results. Temperament clusters with unique dimensional profiles were specifically associated with different anxiety disorders in this study. These results suggest that TCI-R could offer a valuable dimensional method for predicting the risk of anxiety disorders in diverse depressed patients. Copyright © 2018 Elsevier B.V. All rights reserved.

  14. VizieR Online Data Catalog: 44 SZ-selected galaxy clusters ACT observations (Sifon+, 2016)

    Science.gov (United States)

    Sifon, C.; Battaglia, N.; Hasselfield, M.; Menanteau, F.; Barrientos, L. F.; Bond, J. R.; Crichton, D.; Devlin, M. J.; Dunner, R.; Hilton, M.; Hincks, A. D.; Hlozek, R.; Huffenberger, K. M.; Hughes, J. P.; Infante, L.; Kosowsky, A.; Marsden, D.; Marriage, T. A.; Moodley, K.; Niemack, M. D.; Page, L. A.; Spergel, D. N.; Staggs, S. T.; Trac, H.; Wollack, E. J.

    2017-11-01

    ACT is a 6-metre off-axis Gregorian telescope located at an altitude of 5200um in the Atacama desert in Chile, designed to observe the CMB at arcminute resolution. Galaxy clusters were detected in the 148GHz band by matched-filtering the maps with the pressure profile suggested by Arnaud et al. (2010A&A...517A..92A), fit to X-ray selected local (zGMOS) on the Gemini-South telescope, split in semesters 2011B (ObsID:GS-2011B-C-1, PI:Barrientos/Menanteau) and 2012A (ObsID:GS-2012A-C-1, PI:Menanteau), prioritizing clusters in the cosmological sample at 0.3clusters in S82 with the Robert Stobie Spectrograph (RSS) on the Southern African Large Telescope (SALT), using MOS. Details of these observations are given in Kirk et al. (2015, Cat. J/MNRAS/449/4010). In order to enlarge the sample of studied clusters and member galaxies, we also compiled archival data for the equatorial sample. (1 data file).

  15. Vitamin D prenatal programming of childhood metabolomics profiles at age 3 y

    DEFF Research Database (Denmark)

    Blighe, Kevin; Chawes, Bo L; Kelly, Rachel S

    2017-01-01

    was to analyze the programming role of in utero vitamin D exposure on children's metabolomics profiles.Design: First, unsupervised clustering was done with plasma metabolomics profiles from a case-control subset of 245 children aged 3 y with and without asthma from the Vitamin D Antenatal Asthma Reduction Trial...... children can be clustered into distinct biologically meaningful groups by their metabolomics profiles. The clusters differed in concentrations of inflammatory mediators, and cluster membership was influenced by in utero vitamin D exposure, suggesting a prenatal programming role of vitamin D on the child...

  16. A comparative study of the effect of green tea and sour tea on blood pressure and lipid profile in healthy adult men

    Directory of Open Access Journals (Sweden)

    Marzieh Kafeshani

    2017-06-01

    Full Text Available BACKGROUND: Cardiovascular diseases (CVD are a set of metabolic disorders affecting heart and blood vessels. Green tea and sour tea (Hibiscus sabdariffa L. have attracted significant attention recently due to their high popularity, nutrient profile and therapeutic effects. The aim of the present study was to compare the effects of green tea and sour tea supplementation on blood pressure and lipid profile in healthy adult men. METHODS: This randomized, double-blind, placebo-controlled trial included 54 healthy adult men. The participants were randomly assigned to two intervention groups receiving 450 mg green tea or sour tea and one placebo group which consumed 450 mg placebo (maltodextrin for 6 weeks. Blood pressure, lipid profile, dietary intake and physical activity were measured pre- and post-intervention and compared. RESULTS: After 6 weeks of intervention, sour tea supplementation led to a significant decrease in systolic blood pressure (SBP compared with the placebo group. However, we faild to find any significant difference in SBP between green tea and control groups. Also, no significant changes were observed in diastolic blood pressure (DBP and lipid profile between the three groups. In comparison with baseline, there was a significant increase in the mean level of serum high-density lipoprotein cholesterol (HDL-C in green tea and sour tea groups. Also, the interventions resulted in significant decrease in the mean levels of serum total cholesterol (TC and low-density lipoprotein cholesterol (LDL-C and DBP in the sour tea group compared with the pre-intervention value. CONCLUSION: On the basis of our findings, sour tea supplementation led to decreased SBP in healthy men compared with the placebo, but there was no significant difference between their effects on DBP and lipid profile

  17. Interaction of rare gas clusters in intense laser field

    International Nuclear Information System (INIS)

    Dobosz, Sandrine

    1998-01-01

    Rare gas cluster jet targets have only been scarcely studied in strong laser fields. This is surprising since their properties are particularly appealing. Although considered as a gas phase target, the local density within clusters is comparable to that of the bulk. Intense irradiation of clusters produces a plasma thereby giving rise to strong collisional heating. This explains, in particular, the observation of very high fragment charge states and the generation of X-rays in the keV energy range. The complete set of our experimental results shows that the intra-cluster atoms are first ionised by tunnel ionisation followed by massive electron impact ionisation. Thus, for Xenon clusters, we have observed up to 30-fold charged. The most energetic electrons leave the cluster which contributes to a positive charge build-up on the cluster surface. The plasma expands under the combined action of the Coulomb and kinetic pressures. The contribution of each pressure depends on the cluster size and we show that the Coulomb pressure is prevailing for the smallest sizes. This scenario explains the ejection of fragments with energies of up to lMeV. We have also performed a high resolution X-ray study to explore in situ the properties of the plasma. These studies underline the importance of electron-ion collisions and allow to deterrnine the mean charge states of the emitting ions. Finally, we have developed a model, describing the cluster expansion, which confirms our experimental observations. (author) [fr

  18. WSC-2: a subchannel dryout correlation for water-cooled clusters over the pressure range 3.4-15.9 MPA (500-2300 PSIA)

    International Nuclear Information System (INIS)

    Bowring, R.W.

    1979-05-01

    WSC-2 is a subchannel dryout correlation for use with subchannel analysis computer codes such as HAMBO. It was optimised from 1074 experimental data points from 54 clusters simulating Pressure Tube Reactor, BWR and PWR geometries and covering the pressure range 3.4-15.9 MPa. The correlation errors were(a) PWR - type data: RMS 8.8%, Mean 0.2%,(b) all classes of data: RMS 7.2%, Mean - 0.3%. This represents a significant improvement over the other correlations used for reactor assessment with which it has been compared. (author)

  19. Globular Cluster Candidates for Hosting a Central Black Hole

    Science.gov (United States)

    Noyola, Eva

    2009-07-01

    We are continuing our study of the dynamical properties of globular clusters and we propose to obtain surface brightness profiles for high concentration clusters. Our results to date show that the distribution of central surface brightness slopes do not conform to standard models. This has important implications for how they form and evolve, and suggest the possible presence of central intermediate-mass black holes. From our previous archival proposals {AR-9542 and AR-10315}, we find that many high concentration globular clusters do not have flat cores or steep central cusps, instead they show weak cusps. Numerical simulations suggest that clusters with weak cusps may harbor intermediate-mass black holes and we have one confirmation of this connection with omega Centauri. This cluster shows a shallow cusp in its surface brightness profile, while kinematical measurements suggest the presence of a black hole in its center. Our goal is to extend these studies to a sample containing 85% of the Galactic globular clusters with concentrations higher than 1.7 and look for objects departing from isothermal behavior. The ACS globular cluster survey {GO-10775} provides enough objects to have an excellent coverage of a wide range of galactic clusters, but it contains only a couple of the ones with high concentration. The proposed sample consists of clusters whose light profile can only be adequately measured from space-based imaging. This would take us close to completeness for the high concentration cases and therefore provide a more complete list of candidates for containing a central black hole. The dataset will also be combined with our existing kinematic measurements and enhanced with future kinematic studies to perform detailed dynamical modeling.

  20. Cognitive Clusters in Specific Learning Disorder.

    Science.gov (United States)

    Poletti, Michele; Carretta, Elisa; Bonvicini, Laura; Giorgi-Rossi, Paolo

    The heterogeneity among children with learning disabilities still represents a barrier and a challenge in their conceptualization. Although a dimensional approach has been gaining support, the categorical approach is still the most adopted, as in the recent fifth edition of the Diagnostic and Statistical Manual of Mental Disorders. The introduction of the single overarching diagnostic category of specific learning disorder (SLD) could underemphasize interindividual clinical differences regarding intracategory cognitive functioning and learning proficiency, according to current models of multiple cognitive deficits at the basis of neurodevelopmental disorders. The characterization of specific cognitive profiles associated with an already manifest SLD could help identify possible early cognitive markers of SLD risk and distinct trajectories of atypical cognitive development leading to SLD. In this perspective, we applied a cluster analysis to identify groups of children with a Diagnostic and Statistical Manual-based diagnosis of SLD with similar cognitive profiles and to describe the association between clusters and SLD subtypes. A sample of 205 children with a diagnosis of SLD were enrolled. Cluster analyses (agglomerative hierarchical and nonhierarchical iterative clustering technique) were used successively on 10 core subtests of the Wechsler Intelligence Scale for Children-Fourth Edition. The 4-cluster solution was adopted, and external validation found differences in terms of SLD subtype frequencies and learning proficiency among clusters. Clinical implications of these findings are discussed, tracing directions for further studies.

  1. Family and academic performance: identifying high school student profiles

    Directory of Open Access Journals (Sweden)

    Alicia Aleli Chaparro Caso López

    2016-01-01

    Full Text Available The objective of this study was to identify profiles of high school students, based on variables related to academic performance, socioeconomic status, cultural capital and family organization. A total of 21,724 high school students, from the five municipalities of the state of Baja California, took part. A K-means cluster analysis was performed to identify the profiles. The analyses identified two clearly-defined clusters: Cluster 1 grouped together students with high academic performance and who achieved higher scores for socioeconomic status, cultural capital and family involvement, whereas Cluster 2 brought together students with low academic achievement, and who also obtained lower scores for socioeconomic status and cultural capital, and had less family involvement. It is concluded that the family variables analyzed form student profiles that can be related to academic achievement.

  2. WAIS-III index score profiles in the Canadian standardization sample.

    Science.gov (United States)

    Lange, Rael T

    2007-01-01

    Representative index score profiles were examined in the Canadian standardization sample of the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III). The identification of profile patterns was based on the methodology proposed by Lange, Iverson, Senior, and Chelune (2002) that aims to maximize the influence of profile shape and minimize the influence of profile magnitude on the cluster solution. A two-step cluster analysis procedure was used (i.e., hierarchical and k-means analyses). Cluster analysis of the four index scores (i.e., Verbal Comprehension [VCI], Perceptual Organization [POI], Working Memory [WMI], Processing Speed [PSI]) identified six profiles in this sample. Profiles were differentiated by pattern of performance and were primarily characterized as (a) high VCI/POI, low WMI/PSI, (b) low VCI/POI, high WMI/PSI, (c) high PSI, (d) low PSI, (e) high VCI/WMI, low POI/PSI, and (f) low VCI, high POI. These profiles are potentially useful for determining whether a patient's WAIS-III performance is unusual in a normal population.

  3. Kinetic and radiation processes in cluster plasmas

    International Nuclear Information System (INIS)

    Smirnov, B.M.

    1996-01-01

    The analysis of processes is made for a cluster plasma which is a xenon arc plasma of a high pressure with an admixture of tungsten cluster ions. Because cluster ions emit radiation, this system is a light source which parameters are determined by various processes such as heat release and transport of charged particles in the plasma, radiative processes involving clusters, processes of cluster evaporation and attachment of atoms to it that leads to an equilibrium between clusters and vapor of their atoms, processes of cluster generation, processes of the ionization equilibrium between cluster ions and plasma electrons, transport of cluster ions in the discharge plasma in all directions. These processes govern by properties of a specific cluster plasma under consideration. (author)

  4. Analysis of protein profiles using fuzzy clustering methods

    DEFF Research Database (Denmark)

    Karemore, Gopal Raghunath; Ukendt, Sujatha; Rai, Lavanya

    The tissue protein profiles of healthy volunteers and volunteers with cervical cancer were recorded using High Performance Liquid Chromatography combined with Laser Induced Fluorescence  technique  (HPLC-LIF)  developed  in  our  lab.      We analyzed      the protein profile data using different...

  5. Weak-Lensing Mass Calibration of the Atacama Cosmology Telescope Equatorial Sunyaev-Zeldovich Cluster Sample with the Canada-France-Hawaii Telescope Stripe 82 Survey

    Science.gov (United States)

    Battaglia, N.; Leauthaud, A.; Miyatake, H.; Hasseleld, M.; Gralla, M. B.; Allison, R.; Bond, J. R.; Calabrese, E.; Crichton, D.; Devlin, M. J.; hide

    2016-01-01

    Mass calibration uncertainty is the largest systematic effect for using clustersof galaxies to constrain cosmological parameters. We present weak lensing mass measurements from the Canada-France-Hawaii Telescope Stripe 82 Survey for galaxy clusters selected through their high signal-to-noise thermal Sunyaev-Zeldovich (tSZ) signal measured with the Atacama Cosmology Telescope (ACT). For a sample of 9 ACT clusters with a tSZ signal-to-noise greater than five, the average weak lensing mass is (4.8 plus or minus 0.8) times 10 (sup 14) solar mass, consistent with the tSZ mass estimate of (4.7 plus or minus 1.0) times 10 (sup 14) solar mass, which assumes a universal pressure profile for the cluster gas. Our results are consistent with previous weak-lensing measurements of tSZ-detected clusters from the Planck satellite. When comparing our results, we estimate the Eddington bias correction for the sample intersection of Planck and weak-lensing clusters which was previously excluded.

  6. Effects of high hydrostatic pressure and thermal processing on bioactive compounds, antioxidant activity, and volatile profile of mulberry juice.

    Science.gov (United States)

    Wang, Fan; Du, Bao-Lei; Cui, Zheng-Wei; Xu, Li-Ping; Li, Chun-Yang

    2017-03-01

    The aim of this study was to investigate the effects of high hydrostatic pressure and thermal processing on microbiological quality, bioactive compounds, antioxidant activity, and volatile profile of mulberry juice. High hydrostatic pressure processing at 500 MPa for 10 min reduced the total viable count from 4.38 log cfu/ml to nondetectable level and completely inactivated yeasts and molds in raw mulberry juice, ensuring the microbiological safety as thermal processing at 85 ℃ for 15 min. High hydrostatic pressure processing maintained significantly (p hydrostatic pressure processing enhanced the volatile compound concentrations of mulberry juice while thermal processing reduced them in comparison with the control. These results suggested that high hydrostatic pressure processing could be an alternative to conventional thermal processing for production of high-quality mulberry juice.

  7. Effects of sub-lethal high-pressure homogenization treatment on the outermost cellular structures and the volatile-molecule profiles of two strains of probiotic lactobacilli.

    Science.gov (United States)

    Tabanelli, Giulia; Vernocchi, Pamela; Patrignani, Francesca; Del Chierico, Federica; Putignani, Lorenza; Vinderola, Gabriel; Reinheimer, Jorge A; Gardini, Fausto; Lanciotti, Rosalba

    2015-01-01

    Applying sub-lethal levels of high-pressure homogenization (HPH) to lactic acid bacteria has been proposed as a method of enhancing some of their functional properties. Because the principal targets of HPH are the cell-surface structures, the aim of this study was to examine the effect of sub-lethal HPH treatment on the outermost cellular structures and the proteomic profiles of two known probiotic bacterial strains. Moreover, the effect of HPH treatment on the metabolism of probiotic cells within a dairy product during its refrigerated storage was investigated using SPME-GC-MS. Transmission electron microscopy was used to examine the microstructural changes in the outermost cellular structures due to HPH treatment. These alterations may be involved in the changes in some of the technological and functional properties of the strains that were observed after pressure treatment. Moreover, the proteomic profiles of the probiotic strains treated with HPH and incubated at 37°C for various periods showed different peptide patterns compared with those of the untreated cells. In addition, there were differences in the peaks that were observed in the low-mass spectral region (2000-3000 Da) of the spectral profiles of the control and treated samples. Due to pressure treatment, the volatile-molecule profiles of buttermilk inoculated with treated or control cells and stored at 4°C for 30 days exhibited overall changes in the aroma profile and in the production of molecules that improved its sensory profile, although the two different species imparted specific fingerprints to the product. The results of this study will contribute to understanding the changes that occur in the outermost cellular structures and the metabolism of LAB in response to HPH treatment. The findings of this investigation may contribute to elucidating the relationships between these changes and the alterations of the technological and functional properties of LAB induced by pressure treatment.

  8. X-ray cluster Abell 744

    International Nuclear Information System (INIS)

    Kurtz, M.J.; Huchra, J.P.; Beers, T.C.; Geller, M.J.; Gioia, I.M.

    1985-01-01

    X-ray and optical observations of the cluster of galaxies Abell 744 are presented. The X-ray flux (assuming H(0) = 100 km/s per Mpc) is about 9 x 10 to the 42nd erg/s. The X-ray source is extended, but shows no other structure. Photographic photometry (in Kron-Cousins R), calibrated by deep CCD frames, is presented for all galaxies brighter than 19th magnitude within 0.75 Mpc of the cluster center. The luminosity function is normal, and the isopleths show little evidence of substructure near the cluster center. The cluster has a dominant central galaxy, which is classified as a normal brightest-cluster elliptical on the basis of its luminosity profile. New redshifts were obtained for 26 galaxies in the vicinity of the cluster center; 20 appear to be cluster members. The spatial distribution of redshifts is peculiar; the dispersion within the 150 kpc core radius is much greater than outside. Abell 744 is similar to the nearby cluster Abell 1060. 31 references

  9. Ionization of nitrogen cluster beam

    International Nuclear Information System (INIS)

    Yano, Katsuki; Be, S.H.; Enjoji, Hiroshi; Okamoto, Kosuke

    1975-01-01

    A nitrogen cluster beam (neutral particle intensity of 28.6 mAsub(eq)) is ionized by electron collisions in a Bayard-Alpert gauge type ionizer. The extraction efficiency of about 65% is obtained at an electron current of 10 mA with an energy of 50 eV. The mean cluster size produced at a pressure of 663 Torr and temperature of 77.3 K is 2x10 5 molecules per cluster. By the Coulomb repulsion force, multiply ionized cluster ions are broken up into smaller fragments and the cluster ion size reduces to one-fourth at an electron current of 15 mA. Mean neutral cluster sizes depend strongly on the initial degree of saturation PHI 0 and are 2x10 5 , 7x10 4 and 3x10 4 molecules per cluster at PHI 0 's of 0.87, 0.66 and 0.39, respectively. (auth.)

  10. Effects of carbonyl bond, metal cluster dissociation, and evaporation rates on predictions of nanotube production in high-pressure carbon monoxide

    Science.gov (United States)

    Scott, Carl D.; Smalley, Richard E.

    2003-01-01

    The high-pressure carbon monoxide (HiPco) process for producing single-wall carbon nanotubes (SWNTs) uses iron pentacarbonyl as the source of iron for catalyzing the Boudouard reaction. Attempts using nickel tetracarbonyl led to no production of SWNTs. This paper discusses simulations at a constant condition of 1300 K and 30 atm in which the chemical rate equations are solved for different reaction schemes. A lumped cluster model is developed to limit the number of species in the models, yet it includes fairly large clusters. Reaction rate coefficients in these schemes are based on bond energies of iron and nickel species and on estimates of chemical rates for formation of SWNTs. SWNT growth is measured by the conformation of CO2. It is shown that the production of CO2 is significantly greater for FeCO because of its lower bond energy as compared with that of NiCO. It is also shown that the dissociation and evaporation rates of atoms from small metal clusters have a significant effect on CO2 production. A high rate of evaporation leads to a smaller number of metal clusters available to catalyze the Boudouard reaction. This suggests that if CO reacts with metal clusters and removes atoms from them by forming MeCO, this has the effect of enhancing the evaporation rate and reducing SWNT production. The study also investigates some other reactions in the model that have a less dramatic influence.

  11. Measuring the Mean and Scatter of the X-ray Luminosity -- Optical Richness Relation for maxBCG Galaxy Clusters

    Energy Technology Data Exchange (ETDEWEB)

    Rykoff, E.S.; McKay, T.A.; Becker, M.A.; Evrard, A.; Johnston, D.E.; Koester, B.P.; Rozo, E.; Sheldon, E.S.; Wechsler, Risa H.

    2007-10-02

    We interpret and model the statistical weak lensing measurements around 130,000 groups and clusters of galaxies in the Sloan Digital Sky Survey presented by Sheldon et al. (2007). We present non-parametric inversions of the 2D shear profiles to the mean 3D cluster density and mass profiles in bins of both optical richness and cluster i-band luminosity. Since the mean cluster density profile is proportional to the cluster-mass correlation function, the mean profile is spherically symmetric by the assumptions of large-scale homogeneity and isotropy. We correct the inferred 3D profiles for systematic effects, including non-linear shear and the fact that cluster halos are not all precisely centered on their brightest galaxies. We also model the measured cluster shear profile as a sum of contributions from the brightest central galaxy, the cluster dark matter halo, and neighboring halos. We infer the relations between mean cluster virial mass and optical richness and luminosity over two orders of magnitude in cluster mass; the virial mass at fixed richness or luminosity is determined with a precision of {approx} 13% including both statistical and systematic errors. We also constrain the halo concentration parameter and halo bias as a function of cluster mass; both are in good agreement with predictions from N-body simulations of LCDM models. The methods employed here will be applicable to deeper, wide-area optical surveys that aim to constrain the nature of the dark energy, such as the Dark Energy Survey, the Large Synoptic Survey Telescope and space-based surveys.

  12. Diversity in the stellar velocity dispersion profiles of a large sample of brightest cluster galaxies z ≤ 0.3

    Science.gov (United States)

    Loubser, S. I.; Hoekstra, H.; Babul, A.; O'Sullivan, E.

    2018-06-01

    We analyse spatially resolved deep optical spectroscopy of brightestcluster galaxies (BCGs) located in 32 massive clusters with redshifts of 0.05 ≤ z ≤ 0.30 to investigate their velocity dispersion profiles. We compare these measurements to those of other massive early-type galaxies, as well as central group galaxies, where relevant. This unique, large sample extends to the most extreme of massive galaxies, spanning MK between -25.7 and -27.8 mag, and host cluster halo mass M500 up to 1.7 × 1015 M⊙. To compare the kinematic properties between brightest group and cluster members, we analyse similar spatially resolved long-slit spectroscopy for 23 nearby brightest group galaxies (BGGs) from the Complete Local-Volume Groups Sample. We find a surprisingly large variety in velocity dispersion slopes for BCGs, with a significantly larger fraction of positive slopes, unique compared to other (non-central) early-type galaxies as well as the majority of the brightest members of the groups. We find that the velocity dispersion slopes of the BCGs and BGGs correlate with the luminosity of the galaxies, and we quantify this correlation. It is not clear whether the full diversity in velocity dispersion slopes that we see is reproduced in simulations.

  13. Clustering Game Behavior Data

    DEFF Research Database (Denmark)

    Bauckhage, C.; Drachen, Anders; Sifa, Rafet

    2015-01-01

    of the causes, the proliferation of behavioral data poses the problem of how to derive insights therefrom. Behavioral data sets can be large, time-dependent and high-dimensional. Clustering offers a way to explore such data and to discover patterns that can reduce the overall complexity of the data. Clustering...... and other techniques for player profiling and play style analysis have, therefore, become popular in the nascent field of game analytics. However, the proper use of clustering techniques requires expertise and an understanding of games is essential to evaluate results. With this paper, we address game data...... scientists and present a review and tutorial focusing on the application of clustering techniques to mine behavioral game data. Several algorithms are reviewed and examples of their application shown. Key topics such as feature normalization are discussed and open problems in the context of game analytics...

  14. Cerebrospinal fluid biomarkers profile of idiopathic normal pressure hydrocephalus.

    Science.gov (United States)

    Schirinzi, Tommaso; Sancesario, Giulia Maria; Di Lazzaro, Giulia; D'Elia, Alessio; Imbriani, Paola; Scalise, Simona; Pisani, Antonio

    2018-04-01

    Idiopathic normal pressure hydrocephalus (iNPH) is a disabling neurological disorder whose potential treatability is significantly limited by diagnostic uncertainty. In fact, typical clinical presentation occurs at late phases of disease, when CSF shunting could be ineffective. In recent years, measurement of different CSF proteins, whose concentration directly reflects neuropathological changes of CNS, has significantly improved both diagnostic timing and accuracy of neurodegenerative disease. Unfortunately iNPH lacks neuropathological hallmarks allowing the identification of specific disease biomarkers. However, neuropathology of iNPH is so rich and heterogeneous that many processes can be tracked in CSF, including Alzheimer's disease core pathology, subcortical degeneration, neuroinflammation and vascular dysfunction. Indeed, a huge number of CSF biomarkers have been analyzed in iNPH patients, but a unifying profile has not been provided yet. In this brief survey, we thus attempted to summarize the main findings in the field of iNPH CSF biomarkers, aimed at outlining a synthetic model. Although defined cut-off values for biomarkers are not available, a better knowledge of CSF characteristics may definitely assist in diagnosing the disease.

  15. Testing Numerical Models of Cool Core Galaxy Cluster Formation with X-Ray Observations

    Science.gov (United States)

    Henning, Jason W.; Gantner, Brennan; Burns, Jack O.; Hallman, Eric J.

    2009-12-01

    Using archival Chandra and ROSAT data along with numerical simulations, we compare the properties of cool core and non-cool core galaxy clusters, paying particular attention to the region beyond the cluster cores. With the use of single and double β-models, we demonstrate a statistically significant difference in the slopes of observed cluster surface brightness profiles while the cluster cores remain indistinguishable between the two cluster types. Additionally, through the use of hardness ratio profiles, we find evidence suggesting cool core clusters are cooler beyond their cores than non-cool core clusters of comparable mass and temperature, both in observed and simulated clusters. The similarities between real and simulated clusters supports a model presented in earlier work by the authors describing differing merger histories between cool core and non-cool core clusters. Discrepancies between real and simulated clusters will inform upcoming numerical models and simulations as to new ways to incorporate feedback in these systems.

  16. Customer Clustering Based on Customer Purchasing Sequence Data

    OpenAIRE

    Yen-Chung Liu; Yen-Liang Chen

    2017-01-01

    Customer clustering has become a priority for enterprises because of the importance of customer relationship management. Customer clustering can improve understanding of the composition and characteristics of customers, thereby enabling the creation of appropriate marketing strategies for each customer group. Previously, different customer clustering approaches have been proposed according to data type, namely customer profile data, customer value data, customer transaction data, and customer...

  17. Comparing the effect of pressure and temperature on ion mobilities

    International Nuclear Information System (INIS)

    Tabrizchi, Mahmoud; Rouholahnejad, Fereshteh

    2005-01-01

    The effect of pressure on ion mobilities has been investigated and compared with that of temperature. In this connection, an ion mobility spectrometry (IMS) cell, which employs a corona discharge as the ionization source, has been designed and constructed to allow varying pressure inside the drift region. IMS spectra were recorded at various pressures ranging from 15 Torr up to atmospheric pressure. The results show that IMS peaks shift perfectly linear with pressure which is in excellent agreement with the ion mobility theory. However, experimental ion mobilities versus temperature show deviation from the theoretical trend. The deviation is attributed to formation of clusters. The different behaviour of pressure and temperature was explained on the basis of the different impact of pressure and temperature on hydration and clustering of ions. Pressure affects the clustering reactions linearly but temperature affects it exponentially

  18. Galaxy Kinematics and Mass Calibration in Massive SZE Selected Galaxy Clusters to z=1.3

    Energy Technology Data Exchange (ETDEWEB)

    Capasso, R.; et al.

    2017-11-27

    The galaxy phase-space distribution in galaxy clusters provides insights into the formation and evolution of cluster galaxies, and it can also be used to measure cluster mass profiles. We present a dynamical study based on $\\sim$3000 passive, non-emission line cluster galaxies drawn from 110 galaxy clusters. The galaxy clusters were selected using the Sunyaev-Zel'dovich effect (SZE) in the 2500 deg$^2$ SPT-SZ survey and cover the redshift range $0.2 < z < 1.3$. We model the clusters using the Jeans equation, while adopting NFW mass profiles and a broad range of velocity dispersion anisotropy profiles. The data prefer velocity dispersion anisotropy profiles that are approximately isotropic near the center and increasingly radial toward the cluster virial radius, and this is true for all redshifts and masses we study. The pseudo-phase-space density profile of the passive galaxies is consistent with expectations for dark matter particles and subhalos from cosmological $N$-body simulations. The dynamical mass constraints are in good agreement with external mass estimates of the SPT cluster sample from either weak lensing, velocity dispersions, or X-ray $Y_X$ measurements. However, the dynamical masses are lower (at the 2.2$\\sigma$ level) when compared to the mass calibration favored when fitting the SPT cluster data to a LCDM model with external cosmological priors, including CMB anisotropy data from Planck. The tension grows with redshift, where in the highest redshift bin the ratio of dynamical to SPT+Planck masses is $\\eta=0.63^{+0.13}_{-0.08}\\pm0.05$ (statistical and systematic), corresponding to 2.6$\\sigma$ tension.

  19. Real-time measurements of temperature, pressure and moisture profiles in High-Performance Concrete exposed to high temperatures during neutron radiography imaging

    Energy Technology Data Exchange (ETDEWEB)

    Toropovs, N., E-mail: nikolajs.toropovs@rtu.lv [Empa, Swiss Federal Laboratories for Materials Science and Technology, Dübendorf (Switzerland); Riga Technical University, Institute of Materials and Structures, Riga (Latvia); Lo Monte, F. [Politecnico di Milano, Department of Civil and Environmental Engineering, Milan (Italy); Wyrzykowski, M. [Empa, Swiss Federal Laboratories for Materials Science and Technology, Dübendorf (Switzerland); Lodz University of Technology, Department of Building Physics and Building Materials, Lodz (Poland); Weber, B. [Empa, Swiss Federal Laboratories for Materials Science and Technology, Dübendorf (Switzerland); Sahmenko, G. [Riga Technical University, Institute of Materials and Structures, Riga (Latvia); Vontobel, P. [Paul Scherrer Institute, Laboratory for Neutron Scattering and Imaging, Villigen (Switzerland); Felicetti, R. [Politecnico di Milano, Department of Civil and Environmental Engineering, Milan (Italy); Lura, P. [Empa, Swiss Federal Laboratories for Materials Science and Technology, Dübendorf (Switzerland); ETH Zürich, Institute for Building Materials (IfB), Zürich (Switzerland)

    2015-02-15

    High-Performance Concrete (HPC) is particularly prone to explosive spalling when exposed to high temperature. Although the exact causes that lead to spalling are still being debated, moisture transport during heating plays an important role in all proposed mechanisms. In this study, slabs made of high-performance, low water-to-binder ratio mortars with addition of superabsorbent polymers (SAP) and polypropylene fibers (PP) were heated from one side on a temperature-controlled plate up to 550 °C. A combination of measurements was performed simultaneously on the same sample: moisture profiles via neutron radiography, temperature profiles with embedded thermocouples and pore pressure evolution with embedded pressure sensors. Spalling occurred in the sample with SAP, where sharp profiles of moisture and temperature were observed. No spalling occurred when PP-fibers were introduced in addition to SAP. The experimental procedure described here is essential for developing and verifying numerical models and studying measures against fire spalling risk in HPC.

  20. TESTING STRICT HYDROSTATIC EQUILIBRIUM IN SIMULATED CLUSTERS OF GALAXIES: IMPLICATIONS FOR A1689

    International Nuclear Information System (INIS)

    Molnar, S. M.; Umetsu, K.; Chiu, I.-N.; Chen, P.; Hearn, N.; Broadhurst, T.; Bryan, G.; Shang, C.

    2010-01-01

    Accurate mass determination of clusters of galaxies is crucial if they are to be used as cosmological probes. However, there are some discrepancies between cluster masses determined based on gravitational lensing and X-ray observations assuming strict hydrostatic equilibrium (i.e., the equilibrium gas pressure is provided entirely by thermal pressure). Cosmological simulations suggest that turbulent gas motions remaining from hierarchical structure formation may provide a significant contribution to the equilibrium pressure in clusters. We analyze a sample of massive clusters of galaxies drawn from high-resolution cosmological simulations and find a significant contribution (20%-45%) from non-thermal pressure near the center of relaxed clusters, and, in accord with previous studies, a minimum contribution at about 0.1 R vir , growing to about 30%-45% at the virial radius, R vir . Our results strongly suggest that relaxed clusters should have significant non-thermal support in their core region. As an example, we test the validity of strict hydrostatic equilibrium in the well-studied massive galaxy cluster A1689 using the latest high-resolution gravitational lensing and X-ray observations. We find a contribution of about 40% from non-thermal pressure within the core region of A1689, suggesting an alternate explanation for the mass discrepancy: the strict hydrostatic equilibrium is not valid in this region.

  1. HIRFL–CSR internal cluster target

    International Nuclear Information System (INIS)

    Shao, Caojie; Lu, Rongchun; Cai, Xiaohong; Yu, Deyang; Ruan, Fangfang; Xue, Yingli; Zhang, Jianming; Torpokov, D.K.; Nikolenko, D.

    2013-01-01

    Highlights: • An internal cluster target was built and installed at HIRFL–CSR. • The target thickness for H 2 amounts up to 6.6 × 10 12 atoms/cm 2 . • The feasibility and stability of the internal cluster target were verified by on-line experiments. -- Abstract: Since HIRFL–CSR internal cluster target was built, it has played a key role in in-ring experiments at HIRFL–CSR. So far it have been operated with five gas species as targets for scattering experiments, i.e. hydrogen, nitrogen, argon, neon, and krypton. The obtained highest thickness for hydrogen target amounts up to 10 12 atoms/cm 2 , and those of other targets are larger than 10 13 atoms/cm 2 with the background pressure of 10 −11 mbar in CSR. The target thickness can be varied by regulating the nozzle temperature and pressure of the inlet gas. The first online internal target experiment dedicated to investigate radioactive electron capture (REC) process with Xe 54+ ions colliding with the nitrogen target demonstrated the stability and reliability of the internal target system. In addition, hydrogen and krypton were also tested online in recent experiments, which indicate the target system can meet experimental requirements for the thickness of target, pressure in scattering chamber, and long-term stability

  2. A novel clustering and supervising users' profiles method

    Institute of Scientific and Technical Information of China (English)

    Zhu Mingfu; Zhang Hongbin; Song Fangyun

    2005-01-01

    To better understand different users' accessing intentions, a novel clustering and supervising method based on accessing path is presented. This method divides users' interest space to express the distribution of users' interests, and directly to instruct the constructing process of web pages indexing for advanced performance.

  3. [LEVELS OF OBESITY, METABOLIC PROFILE, CONSUMPTION OF TABACO AND BLOOD PRESSURE IN SEDENTARY YOUTHS].

    Science.gov (United States)

    Caamaño Navarrete, Felipe; Alarcón Hormazábal, Manuel; Delgado Floody, Pedro

    2015-11-01

    in Chile, the National Health Survey (ENS) conducted in 2009-2010 reported high prevalence of overweight, sedentary lifestyle, high cholesterol and metabolic syndrome in the population. to determine the prevalence in young sedentary obesity and consumption of tabaco and analyze their association with the metabolic profile, body fat percentage and blood pressure. 125 young sedentary, 26 men and 99 women, aged between 17 and 29 years old were evaluated. Body mass index (BMI), percent body fat (% fat), waist contour (CC), systolic and diastolic blood pressure, total cholesterol, HDL cholesterol (HDL-C), LDL cholesterol (LDL-C), triglycerides: measurements were performed, glycemia and consumption of snuff. HDL-C (p = 0.000) and% MG (p = 0.043) were higher in women. 37.6% of young people turned smoker. 35, 2% of the sample showed excessive malnutrition. Obese subjects had higher levels: waist contour (p = 0.000) and% FM (p = 0.000). When analyzing obesity DC, this showed significant differences in BMI,% fat, systolic and diastolic blood pressure. BMI presented positive association with CC,% fat, total cholesterol, triglycerides, LDL, systolic and diastolic blood pressure (p tabaco in the study sample, while other variables are not high-risk categories, it is an opportune time to intervene and reverse these negative health trends now. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  4. Clustering of Mycobacterium tuberculosis Cases in Acapulco: Spoligotyping and Risk Factors

    Directory of Open Access Journals (Sweden)

    Elizabeth Nava-Aguilera

    2011-01-01

    Full Text Available Recurrence and reinfection of tuberculosis have quite different implications for prevention. We identified 267 spoligotypes of Mycobacterium tuberculosis from consecutive tuberculosis patients in Acapulco, Mexico, to assess the level of clustering and risk factors for clustered strains. Point cluster analysis examined spatial clustering. Risk analysis relied on the Mantel Haenszel procedure to examine bivariate associations, then to develop risk profiles of combinations of risk factors. Supplementary analysis of the spoligotyping data used SpolTools. Spoligotyping identified 85 types, 50 of them previously unreported. The five most common spoligotypes accounted for 55% of tuberculosis cases. One cluster of 70 patients (26% of the series produced a single spoligotype from the Manila Family (Clade EAI2. The high proportion (78% of patients infected with cluster strains is compatible with recent transmission of TB in Acapulco. Geomatic analysis showed no spatial clustering; clustering was associated with a risk profile of uneducated cases who lived in single-room dwellings. The Manila emerging strain accounted for one in every four cases, confirming that one strain can predominate in a hyperendemic area.

  5. Einstein observations of the Hydra A cluster and the efficiency of galaxy formation in groups and clusters

    Science.gov (United States)

    David, L. P.; Arnaud, K. A.; Forman, W.; Jones, C.

    1990-01-01

    The Einstein imaging proportional counter observations of the poor cluster of galaxies centered on the radio galaxy Hydra A are examined. From the surface brightness profile, it is found that the X-ray-emitting gas in the Hydra A cluster must be condensing out of the intracluster medium at a rate of 600 solar masses/yr. This is one of the largest mass deposition rates observed in a cluster of galaxies. The ratio of gas mass to stellar mass is compared for a variety of systems, showing that this ratio correlates with the gas temperature.

  6. Clustering Suicide Attempters: Impulsive-Ambivalent, Well-Planned, or Frequent.

    Science.gov (United States)

    Lopez-Castroman, Jorge; Nogue, Erika; Guillaume, Sebastien; Picot, Marie Christine; Courtet, Philippe

    2016-06-01

    Attempts to predict suicidal behavior within high-risk populations have so far shown insufficient accuracy. Although several psychosocial and clinical features have been consistently associated with suicide attempts, investigations of latent structure in well-characterized populations of suicide attempters are lacking. We analyzed a sample of 1,009 hospitalized suicide attempters that were recruited between 1999 and 2012. Eleven clinically relevant items related to the characteristics of suicidal behavior were submitted to a Hierarchical Ascendant Classification. Phenotypic profiles were compared between the resulting clusters. A decisional tree was constructed to facilitate the differentiation of individuals classified within the first 2 clusters. Most individuals were included in a cluster characterized by less lethal means and planning ("impulse-ambivalent"). A second cluster featured more carefully planned attempts ("well-planned"), more alcohol or drug use before the attempt, and more precautions to avoid interruptions. Finally, a small, third cluster included individuals reporting more attempts ("frequent"), more often serious or violent attempts, and an earlier age at first attempt. Differences across clusters by demographic and clinical characteristics were also found, particularly with the third cluster whose participants had experienced high levels of childhood abuse. Cluster analysis consistently supported 3 distinct clusters of individuals with specific features in their suicidal behaviors and phenotypic profiles that could help clinicians to better focus prevention strategies. © Copyright 2016 Physicians Postgraduate Press, Inc.

  7. Suzaku observations of low surface brightness cluster Abell 1631

    Science.gov (United States)

    Babazaki, Yasunori; Mitsuishi, Ikuyuki; Ota, Naomi; Sasaki, Shin; Böhringer, Hans; Chon, Gayoung; Pratt, Gabriel W.; Matsumoto, Hironori

    2018-06-01

    We present analysis results for a nearby galaxy cluster Abell 1631 at z = 0.046 using the X-ray observatory Suzaku. This cluster is categorized as a low X-ray surface brightness cluster. To study the dynamical state of the cluster, we conduct four-pointed Suzaku observations and investigate physical properties of the Mpc-scale hot gas associated with the A 1631 cluster for the first time. Unlike relaxed clusters, the X-ray image shows no strong peak at the center and an irregular morphology. We perform spectral analysis and investigate the radial profiles of the gas temperature, density, and entropy out to approximately 1.5 Mpc in the east, north, west, and south directions by combining with the XMM-Newton data archive. The measured gas density in the central region is relatively low (a few ×10-4 cm-3) at the given temperature (˜2.9 keV) compared with X-ray-selected clusters. The entropy profile and value within the central region (r clusters. These features are also observed in another low surface brightness cluster, Abell 76. The spatial distributions of galaxies and the hot gas appear to be different. The X-ray luminosity is relatively lower than that expected from the velocity dispersion. A post-merger scenario may explain the observed results.

  8. Sedentary behaviour and clustered metabolic risk in adolescents: the HELENA study.

    Science.gov (United States)

    Rey-López, J P; Bel-Serrat, S; Santaliestra-Pasías, A; de Moraes, A C; Vicente-Rodríguez, G; Ruiz, J R; Artero, E G; Martínez-Gómez, D; Gottrand, F; De Henauw, S; Huybrechts, I; Polito, A; Molnar, D; Manios, Y; Moreno, L A

    2013-10-01

    Although sedentary behaviours are linked with mortality for cardiovascular reasons, it is not clear whether they are negatively related with cardio-metabolic risk factors. The aim was to examine the association between time engaged in television (TV) viewing or playing with videogames and a clustered cardio-metabolic risk in adolescents. Sedentary behaviours and physical activity were assessed in 769 adolescents (376 boys, aged 12.5-17.5 years) from the HELENA-CSS study. We measured systolic blood pressure, HOMA index, triglycerides, TC/HDL-c, VO₂max and the sum of four skinfolds, and a clustered metabolic risk index was computed. A multilevel regression model (by Poisson) was performed to calculate the prevalence ratio of having a clustered metabolic risk. In boys, playing >4 h/day with videogames (weekend) and moderate to vigorous PA (MVPA) was associated with cardio-metabolic risk after adjustment for age, maternal education and MVPA. In contrast, TV viewing was not associated with the presence of cardio-metabolic risk. In boys, playing with videogames may impair cardio-metabolic health during the adolescence. Adolescents should be encouraged to increase their participation in physical activity of at least moderate intensity to obtain a more favourable risk factor profile. Copyright © 2012 Elsevier B.V. All rights reserved.

  9. Stream Clustering of Growing Objects

    Science.gov (United States)

    Siddiqui, Zaigham Faraz; Spiliopoulou, Myra

    We study incremental clustering of objects that grow and accumulate over time. The objects come from a multi-table stream e.g. streams of Customer and Transaction. As the Transactions stream accumulates, the Customers’ profiles grow. First, we use an incremental propositionalisation to convert the multi-table stream into a single-table stream upon which we apply clustering. For this purpose, we develop an online version of K-Means algorithm that can handle these swelling objects and any new objects that arrive. The algorithm also monitors the quality of the model and performs re-clustering when it deteriorates. We evaluate our method on the PKDD Challenge 1999 dataset.

  10. A cluster in a crowded environment: XMM-Newton and Chandra observations of A3558

    Science.gov (United States)

    Rossetti, M.; Ghizzardi, S.; Molendi, S.; Finoguenov, A.

    2007-03-01

    Combining XMM-Newton and Chandra data, we have performed a detailed study of Abell 3558. Our analysis shows that its dynamical history is more complicated than previously thought. We have found some traits typical of cool core clusters (surface brightness peaked at the center, peaked metal abundance profile) and others that are more common in merging clusters, like deviations from spherical symmetry in the thermodynamic quantities of the ICM. This last result has been achieved with a new technique for deriving temperature maps from images. We have also detected a cold front and, with the combined use of XMM-Newton and Chandra, we have characterized its properties, such as the speed and the metal abundance profile across the edge. This cold front is probably due to the sloshing of the core, induced by the perturbation of the gravitational potential associated with a past merger. The hydrodynamic processes related to this perturbation have presumably produced a tail of lower entropy, higher pressure and metal rich ICM, which extends behind the cold front for~500 kpc. The unique characteristics of A3558 are probably due to the very peculiar environment in which it is located: the core of the Shapley supercluster. Appendices A and B are only available in electronic form at http://www.aanda.org

  11. Source selection for cluster weak lensing measurements in the Hyper Suprime-Cam survey

    Science.gov (United States)

    Medezinski, Elinor; Oguri, Masamune; Nishizawa, Atsushi J.; Speagle, Joshua S.; Miyatake, Hironao; Umetsu, Keiichi; Leauthaud, Alexie; Murata, Ryoma; Mandelbaum, Rachel; Sifón, Cristóbal; Strauss, Michael A.; Huang, Song; Simet, Melanie; Okabe, Nobuhiro; Tanaka, Masayuki; Komiyama, Yutaka

    2018-03-01

    We present optimized source galaxy selection schemes for measuring cluster weak lensing (WL) mass profiles unaffected by cluster member dilution from the Subaru Hyper Suprime-Cam Strategic Survey Program (HSC-SSP). The ongoing HSC-SSP survey will uncover thousands of galaxy clusters to z ≲ 1.5. In deriving cluster masses via WL, a critical source of systematics is contamination and dilution of the lensing signal by cluster members, and by foreground galaxies whose photometric redshifts are biased. Using the first-year CAMIRA catalog of ˜900 clusters with richness larger than 20 found in ˜140 deg2 of HSC-SSP data, we devise and compare several source selection methods, including selection in color-color space (CC-cut), and selection of robust photometric redshifts by applying constraints on their cumulative probability distribution function (P-cut). We examine the dependence of the contamination on the chosen limits adopted for each method. Using the proper limits, these methods give mass profiles with minimal dilution in agreement with one another. We find that not adopting either the CC-cut or P-cut methods results in an underestimation of the total cluster mass (13% ± 4%) and the concentration of the profile (24% ± 11%). The level of cluster contamination can reach as high as ˜10% at R ≈ 0.24 Mpc/h for low-z clusters without cuts, while employing either the P-cut or CC-cut results in cluster contamination consistent with zero to within the 0.5% uncertainties. Our robust methods yield a ˜60 σ detection of the stacked CAMIRA surface mass density profile, with a mean mass of M200c = [1.67 ± 0.05(stat)] × 1014 M⊙/h.

  12. Accurate argon cluster-ion sputter yields: Measured yields and effect of the sputter threshold in practical depth-profiling by x-ray photoelectron spectroscopy and secondary ion mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Cumpson, Peter J.; Portoles, Jose F.; Barlow, Anders J.; Sano, Naoko [National EPSRC XPS User' s Service (NEXUS), School of Mechanical and Systems Engineering, Newcastle University, Newcastle upon Tyne, NE1 7RU (United Kingdom)

    2013-09-28

    Argon Gas Cluster-Ion Beam sources are likely to become widely used on x-ray photoelectron spectroscopy and secondary ion mass spectrometry instruments in the next few years. At typical energies used for sputter depth profiling the average argon atom in the cluster has a kinetic energy comparable with the sputter threshold, meaning that for the first time in practical surface analysis a quantitative model of sputter yields near threshold is needed. We develop a simple equation based on a very simple model. Though greatly simplified it is likely to have realistic limiting behaviour and can be made useful for estimating sputter yields by fitting its three parameters to experimental data. We measure argon cluster-ion sputter yield using a quartz crystal microbalance close to the sputter threshold, for silicon dioxide, poly(methyl methacrylate), and polystyrene and (along with data for gold from the existing literature) perform least-squares fits of our new sputter yield equation to this data. The equation performs well, with smaller residuals than for earlier empirical models, but more importantly it is very easy to use in the design and quantification of sputter depth-profiling experiments.

  13. Mechanistic study on lowering the sensitivity of positive atmospheric pressure photoionization mass spectrometric analyses: size-dependent reactivity of solvent clusters.

    Science.gov (United States)

    Ahmed, Arif; Choi, Cheol Ho; Kim, Sunghwan

    2015-11-15

    Understanding the mechanism of atmospheric pressure photoionization (APPI) is important for studies employing APPI liquid chromatography/mass spectrometry (LC/MS). In this study, the APPI mechanism for polyaromatic hydrocarbon (PAH) compounds dissolved in toluene and methanol or water mixture was investigated by use of MS analysis and quantum mechanical simulation. In particular, four different mechanisms that could contribute to the signal reduction were considered based on a combination of MS data and quantum mechanical calculations. The APPI mechanism is clarified by combining MS data and density functional theory (DFT) calculations. To obtain MS data, a positive-mode (+) APPI Q Exactive Orbitrap mass spectrometer was used to analyze each solution. DFT calculations were performed using the general atomic and molecular electronic structure system (GAMESS). The experimental results indicated that methanol significantly reduced the signal in (+) APPI, but no significative signal reduction was observed when water was used as a co-solvent with toluene. The signal reduction is more significant especially for molecular ions than for protonated ions. Therefore, important information about the mechanism of methanol-induced signal reduction in (+) APPI-MS can be gained due its negative impact on APPI efficiency. The size-dependent reactivity of methanol clusters ((CH3 OH)n , n = 1-8) is an important factor in determining the sensitivity of (+) APPI-MS analyses. Clusters can compete with toluene radical ions for electrons. The reactivity increases as the sizes of the methanol clusters increase and this effect can be caused by the size-dependent ionization energy of the solvent clusters. The resulting increase in cluster reactivity explains the flow rate and temperature-dependent signal reduction observed in the analytes. Based on the results presented here, minimizing the sizes of methanol clusters can improve the sensitivity of LC/(+)-APPI-MS. Copyright © 2015 John

  14. [Changes of twenty-four-hour profile blood pressure and its correction of patients with arterial hypertension on the background of combined antihypertensive therapy application].

    Science.gov (United States)

    Solomennchuk, T M; Slaba, N A; Prots'ko, V V; Bedzaĭ, A O

    2014-01-01

    The aim of this research was the study of efficiency and endurance antihypertensive therapy on the basis of fixed combination of enalapril and hydrochlorothiazide (HCTZ) and enalapril and HCTZ in combination with amlodipine according to the twenty-four-hour (? day-and-night) monitoring of blood pressure (? 24H BPM) of patients with arterial hypertension (AH) 2-3 severity. The study included 33 patients with 2-3 grade of hypertension (average age--54,40 ± 3.45 years). All patients performed ? 24H BPM before treatment and after 12 weeks of therapy. The combination of enalapril and HCTZ allowed to achieve target levels of blood pressure in 79% of patients, amlodipine additional purpose--in 86% of patients. We found that this therapy has a corrective effect on daily blood pressure profile, significantly reducing the load pressure and blood pressure variability. During treatment with the combination of enalapril and HCTZ combination of enalapril, HCTZ with amlodipine optimal daily profile of blood pressure after 12 weeks of reaching respectively 63.1% and 71.4% of patients. The treatment with combination of enalapril and HCTZ and adding of amlodipine is characterized by good endurance and high adherence to treatment.

  15. Identifying Children at Risk of Problematic Development: Latent Clusters Among Childhood Arrestees

    NARCIS (Netherlands)

    Geluk, C.A.M.L.; van Domburgh, L.; Doreleijers, T.A.H.; Jansen, L.M.C.; Bouwmeester, S.; Galindo Garre, F.; Vermeiren, R.R.J.M.

    2014-01-01

    The presence of clusters characterized by distinct profiles of individual, family and peer characteristics among childhood arrestees was investigated and cluster membership stability after 2 years was determined. Identification of such clusters in this heterogeneous at-risk group can extend insight

  16. THERMAL AND CHEMICAL EVOLUTIONS OF GALAXY CLUSTERS OBSERVED WITH SUZAKU

    Directory of Open Access Journals (Sweden)

    Kosuke Sato

    2013-12-01

    Full Text Available We studied the properties of the intracluster medium (ICM of galaxy clusters to outer regions observed with Suzaku. The observed temperature dropped by about ~30% from the central region to the virial radius of the clusters. The derived entropy profile agreed with the expectation from simulations within r500, while the entropy profile in r > r500 indicated a flatter slope than the simulations. This would suggest that the cluster outskirts were out of hydrostatic equilibrium. As for the metallicity, we studied the metal abundances from O to Fe up to ~0.5 times the virial radius of galaxy groups and clusters. Comparing the results with supernova nucleosynthesis models, the number ratio of type II to Ia supernovae is estimated to be ~3.5. We also calculated not only Fe, but also O and Mg mass-to-light ratios (MLRs with K-band luminosity. The MLRs in the clusters had a similar feature.

  17. Structure-related clustering of gene expression fingerprints of thp-1 cells exposed to smaller polycyclic aromatic hydrocarbons.

    Science.gov (United States)

    Wan, B; Yarbrough, J W; Schultz, T W

    2008-01-01

    This study was undertaken to test the hypothesis that structurally similar PAHs induce similar gene expression profiles. THP-1 cells were exposed to a series of 12 selected PAHs at 50 microM for 24 hours and gene expressions profiles were analyzed using both unsupervised and supervised methods. Clustering analysis of gene expression profiles revealed that the 12 tested chemicals were grouped into five clusters. Within each cluster, the gene expression profiles are more similar to each other than to the ones outside the cluster. One-methylanthracene and 1-methylfluorene were found to have the most similar profiles; dibenzothiophene and dibenzofuran were found to share common profiles with fluorine. As expression pattern comparisons were expanded, similarity in genomic fingerprint dropped off dramatically. Prediction analysis of microarrays (PAM) based on the clustering pattern generated 49 predictor genes that can be used for sample discrimination. Moreover, a significant analysis of Microarrays (SAM) identified 598 genes being modulated by tested chemicals with a variety of biological processes, such as cell cycle, metabolism, and protein binding and KEGG pathways being significantly (p < 0.05) affected. It is feasible to distinguish structurally different PAHs based on their genomic fingerprints, which are mechanism based.

  18. Influence of reactive gas admixture on transition metal cluster nucleation in a gas aggregation cluster source

    Science.gov (United States)

    Peter, Tilo; Polonskyi, Oleksandr; Gojdka, Björn; Mohammad Ahadi, Amir; Strunskus, Thomas; Zaporojtchenko, Vladimir; Biederman, Hynek; Faupel, Franz

    2012-12-01

    We quantitatively assessed the influence of reactive gases on the formation processes of transition metal clusters in a gas aggregation cluster source. A cluster source based on a 2 in. magnetron is used to study the production rate of titanium and cobalt clusters. Argon served as working gas for the DC magnetron discharge, and a small amount of reactive gas (oxygen and nitrogen) is added to promote reactive cluster formation. We found that the cluster production rate depends strongly on the reactive gas concentration for very small amounts of reactive gas (less than 0.1% of total working gas), and no cluster formation takes place in the absence of reactive species. The influence of discharge power, reactive gas concentration, and working gas pressure are investigated using a quartz micro balance in a time resolved manner. The strong influence of reactive gas is explained by a more efficient formation of nucleation seeds for metal-oxide or nitride than for pure metal.

  19. On the evolution of cluster scaling relations

    International Nuclear Information System (INIS)

    Diemer, Benedikt; Kravtsov, Andrey V.; More, Surhud

    2013-01-01

    Understanding the evolution of scaling relations between the observable properties of clusters and their total mass is key to realizing their potential as cosmological probes. In this study, we investigate whether the evolution of cluster scaling relations is affected by the spurious evolution of mass caused by the evolving reference density with respect to which halo masses are defined (pseudo-evolution). We use the relation between mass, M, and velocity dispersion, σ, as a test case, and show that the deviation from the M-σ relation of cluster-sized halos caused by pseudo-evolution is smaller than 10% for a wide range of mass definitions. The reason for this small impact is a tight relation between the velocity dispersion and mass profiles, σ(profiles, as long as halos are in approximate Jeans equilibrium. Thus, as the outer 'virial' radius used to define the halo mass, R, increases due to pseudo-evolution, halos approximately preserve their M-σ relation. This result highlights the fact that tight scaling relations are the result of tight equilibrium relations between radial profiles of physical quantities. We find exceptions at very small and very large radii, where the profiles deviate from the relations they exhibit at intermediate radii. We discuss the implications of these results for other cluster scaling relations and argue that pseudo-evolution should have a small effect on most scaling relations, except for those that involve the stellar masses of galaxies. In particular, we show that the relation between stellar-mass fraction and total mass is affected by pseudo-evolution and is largely shaped by it for halo masses ≲ 10 14 M ☉ .

  20. Formation mechanism of solute clusters under neutron irradiation in ferritic model alloys and in a reactor pressure vessel steel: clusters of defects; Mecanismes de fragilisation sous irradiation aux neutrons d'alliages modeles ferritiques et d'un acier de cuve: amas de defauts

    Energy Technology Data Exchange (ETDEWEB)

    Meslin-Chiffon, E

    2007-11-15

    The embrittlement of reactor pressure vessel (RPV) under irradiation is partly due to the formation of point defects (PD) and solute clusters. The aim of this work was to gain more insight into the formation mechanisms of solute clusters in low copper ([Cu] = 0.1 wt%) FeCu and FeCuMnNi model alloys, in a copper free FeMnNi model alloy and in a low copper French RPV steel (16MND5). These materials were neutron-irradiated around 300 C in a test reactor. Solute clusters were characterized by tomographic atom probe whereas PD clusters were simulated with a rate theory numerical code calibrated under cascade damage conditions using transmission electron microscopy analysis. The confrontation between experiments and simulation reveals that a heterogeneous irradiation-induced solute precipitation/segregation probably occurs on PD clusters. (author)

  1. Arterial pressure profile in patients with cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens H; Fuglsang, Stefan; Bendtsen, Flemming

    2012-01-01

    Patients with cirrhosis have cardiovascular dysfunction and altered mechanical properties of large and small arteries. This study was undertaken in order to analyze the arterial pressure curve in relation to mean arterial pressure level, stroke volume, and severity of liver disease....

  2. Profiles of mental health care professionals based on work role performance.

    Science.gov (United States)

    Markon, Marie-Pierre; Bamvita, Jean-Marie; Chiocchio, François; Fleury, Marie-Josée

    2017-12-01

    The worldwide burden of mental disorders is considerable, and on the rise, putting pressure on health care systems. Current reforms aim to improve the efficiency of mental health care systems by increasing service integration in communities and strengthening primary mental health care. In this context, mental health care professionals (MHPs) are increasingly required to work on interdisciplinary teams in a variety of settings. Little is known, however, about the profiles of MHPs in relation to their perceived work role performance. MHPs in Quebec (N = 315) from four local service networks completed a self-administered questionnaire eliciting information on individual and team characteristics, as well as team processes and states. Profiles of MHPs were created using a two-step cluster analysis. Five profiles were generated. MHPs belonging to profiles labelled senior medical outpatient specialized care MHPs and senior psychosocial outpatient specialized care MHPs perceived themselves as more performing than MHPs in other profiles. The profile labelled low-collaborators was significantly less performing than all other groups. Two other profiles were identified, positioned between the aforementioned groups in terms of the perceived performance of MHPs: the junior primary care MHPs and the diversified specialized care MHPs. Seniority within the team, delivering specialized type of care, and positive team processes were all features associated with profiles where perceived work performance was high. Overall, this study supports the case for initiatives aimed at improving stability and interdisciplinary collaboration in health teams, especially in primary care.

  3. Study for Relation of Pressure and Aging Degradation during LOCA Test

    International Nuclear Information System (INIS)

    Kim, Jong Seog

    2013-01-01

    As result of this test, it was found that low pressure effect in aging was not significant compared with that of temperature. If temperature profile in LOCA test can satisfy the plant LOCA profile, no further analysis of pressure profile for aging degradation is necessary. For environmental qualification of electric equipment in containment building of nuclear power plant, LOCA test should be applied. During the LOCA test, temperature and pressure of LOCA chamber shall be controlled to meet a requirement of plant specific LOCA profile. It is general to keep LOCA test temperature and pressure above the plant specific LOCA profile. If the test temperature is lower than required profile in some time zone while it is higher in other time zone, calculation of total cumulated test temperature is required to compare with that of plant profile. Arrhenius equation can be applied for calculation of total temperature accumulation. If there is a deviation of pressure between test profile and plant specific profile, can we still use the same rule of temperature? Since the Arrhenius equation can't be applied to pressure, analysis of pressure effect to aging degradation is not easy. Study for relation of pressure and aging degradation during LOCA condition is described herein. To Study an aging degradation effect of pressure during LOCA test, comparison of IR during high LOCA pressure and low LOCA pressure were implemented. We expected low IR in high pressure because it contained a high concentration of oxygen which induces high aging degradation. Contrary to our expectation, IR of low pressure was lower than that of high pressure. It is assumed that high vibration of temperature profile to maintain the low pressure at high temperature induced supply of high enthalpy steam into LOCA chamber

  4. Tropospheric Ozonesonde Profiles at Long-term U.S. Monitoring Sites: 1. A Climatology Based on Self-Organizing Maps

    Science.gov (United States)

    Stauffer, Ryan M.; Thompson, Anne M.; Young, George S.

    2016-01-01

    Sonde-based climatologies of tropospheric ozone (O3) are vital for developing satellite retrieval algorithms and evaluating chemical transport model output. Typical O3 climatologies average measurements by latitude or region, and season. A recent analysis using self-organizing maps (SOM) to cluster ozonesondes from two tropical sites found that clusters of O3 mixing ratio profiles are an excellent way to capture O3variability and link meteorological influences to O3 profiles. Clusters correspond to distinct meteorological conditions, e.g., convection, subsidence, cloud cover, and transported pollution. Here the SOM technique is extended to four long-term U.S. sites (Boulder, CO; Huntsville, AL; Trinidad Head, CA; and Wallops Island, VA) with4530 total profiles. Sensitivity tests on k-means algorithm and SOM justify use of 3 3 SOM (nine clusters). Ateach site, SOM clusters together O3 profiles with similar tropopause height, 500 hPa height temperature, and amount of tropospheric and total column O3. Cluster means are compared to monthly O3 climatologies.For all four sites, near-tropopause O3 is double (over +100 parts per billion by volume; ppbv) the monthly climatological O3 mixing ratio in three clusters that contain 1316 of profiles, mostly in winter and spring.Large midtropospheric deviations from monthly means (6 ppbv, +710 ppbv O3 at 6 km) are found in two of the most populated clusters (combined 3639 of profiles). These two clusters contain distinctly polluted(summer) and clean O3 (fall-winter, high tropopause) profiles, respectively. As for tropical profiles previously analyzed with SOM, O3 averages are often poor representations of U.S. O3 profile statistics.

  5. Constraining hydrostatic mass bias of galaxy clusters with high-resolution X-ray spectroscopy

    Science.gov (United States)

    Ota, Naomi; Nagai, Daisuke; Lau, Erwin T.

    2018-04-01

    Gas motions in galaxy clusters play important roles in determining the properties of the intracluster medium (ICM) and in the constraint of cosmological parameters via X-ray and Sunyaev-Zel'dovich effect observations of galaxy clusters. The Hitomi measurements of gas motions in the core of the Perseus Cluster have provided new insights into the physics in galaxy clusters. The XARM mission, equipped with the Resolve X-ray micro-calorimeter, will continue Hitomi's legacy by measuring ICM motions through Doppler shifting and broadening of emission lines in a larger number of galaxy clusters, and at larger radii. In this work, we investigate how well we can measure bulk and turbulent gas motions in the ICM with XARM, by analyzing mock XARM simulations of galaxy clusters extracted from cosmological hydrodynamic simulations. We assess how photon counts, spectral fitting methods, multiphase ICM structure, deprojections, and region selection affect the measurements of gas motions. We first show that XARM is capable of recovering the underlying spherically averaged turbulent and bulk velocity profiles for dynamically relaxed clusters to within ˜50% with a reasonable amount of photon counts in the X-ray emission lines. We also find that there are considerable azimuthal variations in the ICM velocities, where the velocities measured in a single azimuthal direction can significantly deviate from the true value even in dynamically relaxed systems. Such variation must be taken into account when interpreting data and developing observing strategies. We will discuss the prospect of using the upcoming XARM mission to measure non-thermal pressure and to correct for the hydrostatic mass bias of galaxy clusters. Our results are broadly applicable for future X-ray missions, such as Athena and Lynx.

  6. Constraining hydrostatic mass bias of galaxy clusters with high-resolution X-ray spectroscopy

    Science.gov (United States)

    Ota, Naomi; Nagai, Daisuke; Lau, Erwin T.

    2018-06-01

    Gas motions in galaxy clusters play important roles in determining the properties of the intracluster medium (ICM) and in the constraint of cosmological parameters via X-ray and Sunyaev-Zel'dovich effect observations of galaxy clusters. The Hitomi measurements of gas motions in the core of the Perseus Cluster have provided new insights into the physics in galaxy clusters. The XARM mission, equipped with the Resolve X-ray micro-calorimeter, will continue Hitomi's legacy by measuring ICM motions through Doppler shifting and broadening of emission lines in a larger number of galaxy clusters, and at larger radii. In this work, we investigate how well we can measure bulk and turbulent gas motions in the ICM with XARM, by analyzing mock XARM simulations of galaxy clusters extracted from cosmological hydrodynamic simulations. We assess how photon counts, spectral fitting methods, multiphase ICM structure, deprojections, and region selection affect the measurements of gas motions. We first show that XARM is capable of recovering the underlying spherically averaged turbulent and bulk velocity profiles for dynamically relaxed clusters to within ˜50% with a reasonable amount of photon counts in the X-ray emission lines. We also find that there are considerable azimuthal variations in the ICM velocities, where the velocities measured in a single azimuthal direction can significantly deviate from the true value even in dynamically relaxed systems. Such variation must be taken into account when interpreting data and developing observing strategies. We will discuss the prospect of using the upcoming XARM mission to measure non-thermal pressure and to correct for the hydrostatic mass bias of galaxy clusters. Our results are broadly applicable for future X-ray missions, such as Athena and Lynx.

  7. Calculating Cluster Masses via the Sunyaev-Zel'dovich Effect

    Science.gov (United States)

    Lindley, Ashley; Landry, D.; Bonamente, M.; Joy, M.; Bulbul, E.; Carlstrom, J. E.; Culverhouse, T. L.; Gralla, M.; Greer, C.; Hawkins, D.; Lamb, J. W.; Leitch, E. M.; Marrone, D. P.; Miller, A.; Mroczkowski, T.; Muchovej, S.; Plagge, T.; Woody, D.

    2012-05-01

    Accurate measurements of the total mass of galaxy clusters are key for measuring the cluster mass function and therefore investigating the evolution of the universe. We apply two new methods to measure cluster masses for five galaxy clusters contained within the Brightest Cluster Sample (BCS), an X-ray luminous statistically complete sample of 35 clusters at z=0.15-0.30. These methods distinctively use only observations of the Sunyaev-Zel'dovich (SZ) effect, for which the brightness is redshift independent. At the low redshifts of the BCS, X-ray observations can easily be used to determine cluster masses, providing convenient calibrators for our SZ mass calculations. These clusters have been observed with the Sunyaev-Zel'dovich Array (SZA), an interferometer that is part of the Combined Array for Research in Millimeter-wave Astronomy (CARMA) that has been optimized for accurate measurement of the SZ effect in clusters of galaxies at 30 GHz. One method implements a scaling relation that relates the integrated pressure, Y, as determined by the SZ observations to the mass of the cluster calculated via optical weak lensing. The second method makes use of the Virial theorem to determine the mass given the integrated pressure of the cluster. We find that masses calculated utilizing these methods within a radius r500 are consistent with X-ray masses, calculated by manipulating the surface brightness and temperature data within the same radius, thus concluding that these are viable methods for the determination of cluster masses via the SZ effect. We present preliminary results of our analysis for five galaxy clusters.

  8. Determination of hydrogen cluster velocities and comparison with numerical calculations

    International Nuclear Information System (INIS)

    Täschner, A.; Köhler, E.; Ortjohann, H.-W.; Khoukaz, A.

    2013-01-01

    The use of powerful hydrogen cluster jet targets in storage ring experiments led to the need of precise data on the mean cluster velocity as function of the stagnation temperature and pressure for the determination of the volume density of the target beams. For this purpose a large data set of hydrogen cluster velocity distributions and mean velocities was measured at a high density hydrogen cluster jet target using a trumpet shaped nozzle. The measurements have been performed at pressures above and below the critical pressure and for a broad range of temperatures relevant for target operation, e.g., at storage ring experiments. The used experimental method is described which allows for the velocity measurement of single clusters using a time-of-flight technique. Since this method is rather time-consuming and these measurements are typically interfering negatively with storage ring experiments, a method for a precise calculation of these mean velocities was needed. For this, the determined mean cluster velocities are compared with model calculations based on an isentropic one-dimensional van der Waals gas. Based on the obtained data and the presented numerical calculations, a new method has been developed which allows to predict the mean cluster velocities with an accuracy of about 5%. For this two cut-off parameters defining positions inside the nozzle are introduced, which can be determined for a given nozzle by only two velocity measurements

  9. Embedding piezoresistive pressure sensors to obtain online pressure profiles inside fiber composite laminates.

    Science.gov (United States)

    Moghaddam, Maryam Kahali; Breede, Arne; Brauner, Christian; Lang, Walter

    2015-03-27

    The production of large and complex parts using fiber composite materials is costly due to the frequent formation of voids, porosity and waste products. By embedding different types of sensors and monitoring the process in real time, the amount of wastage can be significantly reduced. This work focuses on developing a knowledge-based method to improve and ensure complete impregnation of the fibers before initiation of the resin cure. Piezoresistive and capacitive pressure sensors were embedded in fiber composite laminates to measure the real-time the pressure values inside the laminate. A change of pressure indicates resin infusion. The sensors were placed in the laminate and the resin was infused by vacuum. The embedded piezoresistive pressure sensors were able to track the vacuum pressure in the fiber composite laminate setup, as well as the arrival of the resin at the sensor. The pressure increase due to closing the resin inlet was also measured. In contrast, the capacitive type of sensor was found to be inappropriate for measuring these quantities. The following study demonstrates real-time monitoring of pressure changes inside the fiber composite laminate, which validate the use of Darcy's law in porous media to control the resin flow during infusion.

  10. Acceleration of cluster and molecular ions by TIARA 3 MV tandem accelerator

    CERN Document Server

    Saitoh, Y; Tajima, S

    2000-01-01

    We succeeded in accelerating molecular and cluster ions (B sub 2 sub - sub 4 , C sub 2 sub - sub 1 sub 0 , O sub 2 , Al sub 2 sub - sub 4 , Si sub 2 sub - sub 4 , Cu sub 2 sub - sub 3 , Au sub 2 sub - sub 3 , LiF, and AlO) to MeV energies with high-intensity beam currents by means of a 3 MV tandem accelerator in the TIARA facility. These cluster ions were generated by a cesium sputter-type negative ion source. We tested three types of carbon sputter cathodes in which graphite powder was compressed with different pressures. The pressure difference affected the generating ratio of clusters generated to single atom ions extracted from the source and it appeared that the high-density cathode was suitable. We also investigated the optimum gas pressure for charge exchange in the tandem high-voltage terminal. Clusters of larger size tend to require lower pressure than do smaller ones. In addition, we were able to obtain doubly charged AlO molecular ions. (authors)

  11. Exploring the Internal Dynamics of Globular Clusters

    Science.gov (United States)

    Watkins, Laura L.; van der Marel, Roeland; Bellini, Andrea; Luetzgendorf, Nora; HSTPROMO Collaboration

    2018-01-01

    Exploring the Internal Dynamics of Globular ClustersThe formation histories and structural properties of globular clusters are imprinted on their internal dynamics. Energy equipartition results in velocity differences for stars of different mass, and leads to mass segregation, which results in different spatial distributions for stars of different mass. Intermediate-mass black holes significantly increase the velocity dispersions at the centres of clusters. By combining accurate measurements of their internal kinematics with state-of-the-art dynamical models, we can characterise both the velocity dispersion and mass profiles of clusters, tease apart the different effects, and understand how clusters may have formed and evolved.Using proper motions from the Hubble Space Telescope Proper Motion (HSTPROMO) Collaboration for a set of 22 Milky Way globular clusters, and our discrete dynamical modelling techniques designed to work with large, high-quality datasets, we are studying a variety of internal cluster properties. We will present the results of theoretical work on simulated clusters that demonstrates the efficacy of our approach, and preliminary results from application to real clusters.

  12. Reliability of transpulmonary pressure-time curve profile to identify tidal recruitment/hyperinflation in experimental unilateral pleural effusion.

    Science.gov (United States)

    Formenti, P; Umbrello, M; Graf, J; Adams, A B; Dries, D J; Marini, J J

    2017-08-01

    The stress index (SI) is a parameter that characterizes the shape of the airway pressure-time profile (P/t). It indicates the slope progression of the curve, reflecting both lung and chest wall properties. The presence of pleural effusion alters the mechanical properties of the respiratory system decreasing transpulmonary pressure (Ptp). We investigated whether the SI computed using Ptp tracing would provide reliable insight into tidal recruitment/overdistention during the tidal cycle in the presence of unilateral effusion. Unilateral pleural effusion was simulated in anesthetized, mechanically ventilated pigs. Respiratory system mechanics and thoracic computed tomography (CT) were studied to assess P/t curve shape and changes in global lung aeration. SI derived from airway pressure (Paw) was compared with that calculated by Ptp under the same conditions. These results were themselves compared with quantitative CT analysis as a gold standard for tidal recruitment/hyperinflation. Despite marked changes in tidal recruitment, mean values of SI computed either from Paw or Ptp were remarkably insensitive to variations of PEEP or condition. After the instillation of effusion, SI indicates a preponderant over-distension effect, not detected by CT. After the increment in PEEP level, the extent of CT-determined tidal recruitment suggest a huge recruitment effect of PEEP as reflected by lung compliance. Both SI in this case were unaffected. We showed that the ability of SI to predict tidal recruitment and overdistension was significantly reduced in a model of altered chest wall-lung relationship, even if the parameter was computed from the Ptp curve profile.

  13. The Behavior of Micro Bubbles and Bubble Cluster in Ultrasound Field

    Science.gov (United States)

    Yoshizawa, Shin; Matsumoto, Yoichiro

    2001-11-01

    Ultrasound is widely applied in the clinical field today, such as ultrasound imaging, Extracorporeal Shock Wave Lithotripsy (ESWL) and so on. It is essential to take a real understanding of the dynamics of micro bubbles and bubble cluster in these applications. Thus we numerically simulate them in ultrasound field in this paper. In the numerical simulation, we consider the thermal behavior inside the bubble and the pressure wave phenomena in the bubble cluster in detail, namely, the evaporation and condensation of liquid at the bubble wall, heat transfer through the bubble wall, diffusion of non-condensable gas inside the bubble and the compressibility of liquid. Initial cluster radius is to 0.5[mm], bubble radius is 1.7[mm], void fraction is 0.1[ambient pressure is 101.3[kPa], temperature is 293[K] and the amplitude of ultrasound is 50[kPa]. We simulate bubble cluster in ultrasound field at various frequencies and we obtain the following conclusions. 1) The maximum pressure inside bubble cluster reaches 5[MPa] and this is much higher than that of a bubble. 2) Bubble cluster behaves like a rigid body acoustically when the frequency of ultrasound is much higher than its natural frequency.

  14. The signal of weak gravitational lensing from galaxy groups and clusters

    Science.gov (United States)

    Markert, Sean

    2017-02-01

    The weak gravitational lensing of galaxy clusters is a valuable tool. The deflection of light around a lens is solely dependent on the underlying distribution of foreground mass, and independent of tracers of mass such as the mass to light ratio and kinematics. As a direct probe of mass, weak lensing serves as an independent calibration of mass-observable relationships. These massive clusters are objects of great interest to astronomers, as their abundance is dependent on the conditions of the early universe, and accurate counts of clusters serve as a test of cosmological model. Upcoming surveys, such as LSST and DES, promise to push the limit of observable weak lensing, detecting clusters and sources at higher redshift than has ever been detected before. This makes accurate counts of clusters of a given mass and redshift, and proper calibration of mass-observable relationships, vital to cosmological studies. We used M> 1013.5 h-1M ⊙ halos from the MultiDark Planck simulation at z 0.5 to study the behavior of the reduced shear in clusters. We generated 2D maps of convergence and shear the halos using the GLAMER lensing library. Using these maps, we simulated observations of randomly placed background sources, and generate azimuthal averages of the shear. This reduced shear profile, and the true reduced shear profile of the halo, is fit using analytical solutions for shear of the NFW, Einasto, and truncated NFW density profile. The masses of these density profiles are then compared to the total halo masses from the halo catalogs. We find that fits to the reduced shear for halos extending past ≈ 2 h-1Mpc are fits to the noise of large scale structure along the line of sight. This noise is largely in the 45° rotated component to the reduced tangential shear, and is a breakdown in the approximation of gtan ≈ gnot required for density profile fitting of clusters. If fits are constrained to a projected radii of < 2 h-1Mpc, we see massively improved fits

  15. Searching remote homology with spectral clustering with symmetry in neighborhood cluster kernels.

    Directory of Open Access Journals (Sweden)

    Ujjwal Maulik

    Full Text Available Remote homology detection among proteins utilizing only the unlabelled sequences is a central problem in comparative genomics. The existing cluster kernel methods based on neighborhoods and profiles and the Markov clustering algorithms are currently the most popular methods for protein family recognition. The deviation from random walks with inflation or dependency on hard threshold in similarity measure in those methods requires an enhancement for homology detection among multi-domain proteins. We propose to combine spectral clustering with neighborhood kernels in Markov similarity for enhancing sensitivity in detecting homology independent of "recent" paralogs. The spectral clustering approach with new combined local alignment kernels more effectively exploits the unsupervised protein sequences globally reducing inter-cluster walks. When combined with the corrections based on modified symmetry based proximity norm deemphasizing outliers, the technique proposed in this article outperforms other state-of-the-art cluster kernels among all twelve implemented kernels. The comparison with the state-of-the-art string and mismatch kernels also show the superior performance scores provided by the proposed kernels. Similar performance improvement also is found over an existing large dataset. Therefore the proposed spectral clustering framework over combined local alignment kernels with modified symmetry based correction achieves superior performance for unsupervised remote homolog detection even in multi-domain and promiscuous domain proteins from Genolevures database families with better biological relevance. Source code available upon request.sarkar@labri.fr.

  16. VHBORE: A code to compute borehole fluid conductivity profiles with pressure changes in the borehole

    International Nuclear Information System (INIS)

    Hale, F.V.; Tsang, C.F.

    1994-06-01

    This report describes the code VHBORE which can be used to model fluid electric conductivity profiles in a borehole intersecting fractured rock under conditions of changing pressure in the well bore. Pressure changes may be due to water level variations caused by pumping or fluid density effects as formation fluid is drawn into the borehole. Previous reports describe the method of estimating the hydrologic behavior of fractured rock using a time series of electric conductivity logs and an earlier code, BORE, to generate electric conductivity logs under constant pressure and flow rate conditions. The earlier model, BORE, assumed a constant flow rate, q i , for each inflow into the well bore. In the present code the user supplies the location, constant pressure, h i , transmissivity, T i , and storativity, S i , for each fracture, as well as the initial water level in the well, h w (0), In addition, the input data contains changes in the water level at later times, Δh w (t), typically caused by turning a pump on or off. The variable density calculation also requires input of the density of each of the inflow fluids, ρ i , and the initial uniform density of the well bore fluid, ρ w (0). These parameters are used to compute the flow rate for each inflow point at each time step. The numerical method of Jacob and Lohman (1952) is used to compute the flow rate into or out of the fractures based on the changes in pressure in the wellbore. A dimensionless function relates flow rate as a function of time in response to an imposed pressure change. The principle of superposition is used to determine the net flow rate from a time series of pressure changes. Additional reading on the relationship between drawdown and flow rate can be found in Earlougher (1977), particularly his Section 4.6, open-quotes Constant-Pressure Flow Testingclose quotes

  17. Cytokine profile determined by data-mining analysis set into clusters of non-small-cell lung cancer patients according to prognosis.

    Science.gov (United States)

    Barrera, L; Montes-Servín, E; Barrera, A; Ramírez-Tirado, L A; Salinas-Parra, F; Bañales-Méndez, J L; Sandoval-Ríos, M; Arrieta, Ó

    2015-02-01

    Immunoregulatory cytokines may play a fundamental role in tumor growth and metastases. Their effects are mediated through complex regulatory networks. Human cytokine profiles could define patient subgroups and represent new potential biomarkers. The aim of this study was to associate a cytokine profile obtained through data mining with the clinical characteristics of patients with advanced non-small-cell lung cancer (NSCLC). We conducted a prospective study of the plasma levels of 14 immunoregulatory cytokines by ELISA and a cytometric bead array assay in 110 NSCLC patients before chemotherapy and 25 control subjects. Cytokine levels and data-mining profiles were associated with clinical, quality of life and pathological outcomes. NSCLC patients had higher levels of interleukin (IL)-6, IL-8, IL-12p70, IL-17a and interferon (IFN)-γ, and lower levels of IL-33 and IL-29 compared with controls. The pro-inflammatory cytokines IL-1b, IL-6 and IL-8 were associated with lower hemoglobin levels, worse functional performance status (Eastern Cooperative Oncology Group, ECOG), fatigue and hyporexia. The anti-inflammatory cytokines IL-4, IL-10 and IL-33 were associated with anorexia and lower body mass index. We identified three clusters of patients according to data-mining analysis with different overall survival (OS; 25.4, 16.8 and 5.09 months, respectively, P = 0.0012). Multivariate analysis showed that ECOG performance status and data-mining clusters were significantly associated with OS (RR 3.59, [95% CI 1.9-6.7], P < 0.001 and 2.2, [1.2-3.8], P = 0.005). Our results provide evidence that complex cytokine networks may be used to identify patient subgroups with different prognoses in advanced NSCLC. These cytokines may represent potential biomarkers, particularly in the immunotherapy era in cancer research. © The Author 2014. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email

  18. Suzaku observations of low surface brightness cluster Abell 1631

    Science.gov (United States)

    Babazaki, Yasunori; Mitsuishi, Ikuyuki; Ota, Naomi; Sasaki, Shin; Böhringer, Hans; Chon, Gayoung; Pratt, Gabriel W.; Matsumoto, Hironori

    2018-04-01

    We present analysis results for a nearby galaxy cluster Abell 1631 at z = 0.046 using the X-ray observatory Suzaku. This cluster is categorized as a low X-ray surface brightness cluster. To study the dynamical state of the cluster, we conduct four-pointed Suzaku observations and investigate physical properties of the Mpc-scale hot gas associated with the A 1631 cluster for the first time. Unlike relaxed clusters, the X-ray image shows no strong peak at the center and an irregular morphology. We perform spectral analysis and investigate the radial profiles of the gas temperature, density, and entropy out to approximately 1.5 Mpc in the east, north, west, and south directions by combining with the XMM-Newton data archive. The measured gas density in the central region is relatively low (a few ×10-4 cm-3) at the given temperature (˜2.9 keV) compared with X-ray-selected clusters. The entropy profile and value within the central region (r < 0.1 r200) are found to be flatter and higher (≳400 keV cm2). The observed bolometric luminosity is approximately three times lower than that expected from the luminosity-temperature relation in previous studies of relaxed clusters. These features are also observed in another low surface brightness cluster, Abell 76. The spatial distributions of galaxies and the hot gas appear to be different. The X-ray luminosity is relatively lower than that expected from the velocity dispersion. A post-merger scenario may explain the observed results.

  19. Functional Status, Quality of Life, and Costs Associated With Fibromyalgia Subgroups: A Latent Profile Analysis.

    Science.gov (United States)

    Luciano, Juan V; Forero, Carlos G; Cerdà-Lafont, Marta; Peñarrubia-María, María Teresa; Fernández-Vergel, Rita; Cuesta-Vargas, Antonio I; Ruíz, José M; Rozadilla-Sacanell, Antoni; Sirvent-Alierta, Elena; Santo-Panero, Pilar; García-Campayo, Javier; Serrano-Blanco, Antoni; Pérez-Aranda, Adrián; Rubio-Valera, María

    2016-10-01

    Although fibromyalgia syndrome (FM) is considered a heterogeneous condition, there is no generally accepted subgroup typology. We used hierarchical cluster analysis and latent profile analysis to replicate Giesecke's classification in Spanish FM patients. The second aim was to examine whether the subgroups differed in sociodemographic characteristics, functional status, quality of life, and in direct and indirect costs. A total of 160 FM patients completed the following measures for cluster derivation: the Center for Epidemiological Studies-Depression Scale, the Trait Anxiety Inventory, the Pain Catastrophizing Scale, and the Control over Pain subscale. Pain threshold was measured with a sphygmomanometer. In addition, the Fibromyalgia Impact Questionnaire-Revised, the EuroQoL-5D-3L, and the Client Service Receipt Inventory were administered for cluster validation. Two distinct clusters were identified using hierarchical cluster analysis ("hypersensitive" group, 69.8% and "functional" group, 30.2%). In contrast, the latent profile analysis goodness-of-fit indices supported the existence of 3 FM patient profiles: (1) a "functional" profile (28.1%) defined as moderate tenderness, distress, and pain catastrophizing; (2) a "dysfunctional" profile (45.6%) defined by elevated tenderness, distress, and pain catastrophizing; and (3) a "highly dysfunctional and distressed" profile (26.3%) characterized by elevated tenderness and extremely high distress and catastrophizing. We did not find significant differences in sociodemographic characteristics between the 2 clusters or among the 3 profiles. The functional profile was associated with less impairment, greater quality of life, and lower health care costs. We identified 3 distinct profiles which accounted for the heterogeneity of FM patients. Our findings might help to design tailored interventions for FM patients.

  20. Classification of Forefoot Plantar Pressure Distribution in Persons with Diabetes: A Novel Perspective for the Mechanical Management of Diabetic Foot?

    Science.gov (United States)

    Deschamps, Kevin; Matricali, Giovanni Arnoldo; Roosen, Philip; Desloovere, Kaat; Bruyninckx, Herman; Spaepen, Pieter; Nobels, Frank; Tits, Jos; Flour, Mieke; Staes, Filip

    2013-01-01

    Background The aim of this study was to identify groups of subjects with similar patterns of forefoot loading and verify if specific groups of patients with diabetes could be isolated from non-diabetics. Methodology/Principal Findings Ninety-seven patients with diabetes and 33 control participants between 45 and 70 years were prospectively recruited in two Belgian Diabetic Foot Clinics. Barefoot plantar pressure measurements were recorded and subsequently analysed using a semi-automatic total mapping technique. Kmeans cluster analysis was applied on relative regional impulses of six forefoot segments in order to pursue a classification for the control group separately, the diabetic group separately and both groups together. Cluster analysis led to identification of three distinct groups when considering only the control group. For the diabetic group, and the computation considering both groups together, four distinct groups were isolated. Compared to the cluster analysis of the control group an additional forefoot loading pattern was identified. This group comprised diabetic feet only. The relevance of the reported clusters was supported by ANOVA statistics indicating significant differences between different regions of interest and different clusters. Conclusion/s Significance There seems to emerge a new era in diabetic foot medicine which embraces the classification of diabetic patients according to their biomechanical profile. Classification of the plantar pressure distribution has the potential to provide a means to determine mechanical interventions for the prevention and/or treatment of the diabetic foot. PMID:24278219

  1. The outskirts of galaxy clusters: astrophysics and cosmology

    Science.gov (United States)

    Morandi, Andrea; Sun, Ming

    2017-08-01

    Exploring the virialization region of galaxy clusters has recently raised the attention of the scientific community, offering a direct view of structure formation. In this talk, I will present recent results on the physical properties of the intracluster medium in the outer volumes of a sample of 320 clusters (0.056 3 keV) in the Chandra archive, with a total integration time of ~20 Ms. We stacked the emission measure profiles of the clusters to detect a signal out to R100. We then measured the average emission measure, gas density and gas fraction, which scale according to the self-similar model of cluster formation. We observe a steepening of the density profiles beyond R500 with slope β~0.68 at R500 and β~1 at R200 and beyond. By tracking the direction of the cosmic filaments where the clusters are embedded, we report that galaxy clusters deviate from spherical symmetry. We finally used, for the first time, the high level of similarity of the emission measure in the cluster outskirts as cosmology proxy. The cosmological parameters are thus constrained assuming that the emission measure profiles at different redshift are weakly self-similar, that is their shape is universal, explicitly allowing for temperature and redshift dependence of the gas fraction. This cosmological test, in combination with Planck+SNIa data, allows us to put a tight constraint on the dark energy models. For a constant-w model, we have w=-1.010±0.030 and Ωm=0.311±0.014, while for a time-evolving equation of state of dark energy w(z) we have Ωm=0.308±0.017, w0=-0.993±0.046 and wa=-0.123±0.400 We checked that our method is robust towards different sources of systematics, including background modelling, outlier measurements, selection effects, inhomogeneities of the gas distribution and cosmic filaments. We also provided for the first time constraints on which definition of cluster boundary radius is more tenable, namely based on a fixed overdensity with respect to the critical

  2. Slingshot mechanism for clusters: Gas density regulates star density in the Orion Nebula Cluster (M42)

    Science.gov (United States)

    Stutz, Amelia M.

    2018-02-01

    We characterize the stellar and gas volume density, potential, and gravitational field profiles in the central ∼0.5 pc of the Orion Nebula Cluster (ONC), the nearest embedded star cluster (or rather, protocluster) hosting massive star formation available for detailed observational scrutiny. We find that the stellar volume density is well characterized by a Plummer profile ρstars(r) = 5755 M⊙ pc- 3 (1 + (r/a)2)- 5/2, where a = 0.36 pc. The gas density follows a cylindrical power law ρgas(R) = 25.9 M⊙ pc- 3 (R/pc)- 1.775. The stellar density profile dominates over the gas density profile inside r ∼ 1 pc. The gravitational field is gas-dominated at all radii, but the contribution to the total field by the stars is nearly equal to that of the gas at r ∼ a. This fact alone demonstrates that the protocluster cannot be considered a gas-free system or a virialized system dominated by its own gravity. The stellar protocluster core is dynamically young, with an age of ∼2-3 Myr, a 1D velocity dispersion of σobs = 2.6 km s-1, and a crossing time of ∼0.55 Myr. This time-scale is almost identical to the gas filament oscillation time-scale estimated recently by Stutz & Gould. This provides strong evidence that the protocluster structure is regulated by the gas filament. The protocluster structure may be set by tidal forces due to the oscillating filamentary gas potential. Such forces could naturally suppress low density stellar structures on scales ≳ a. The analysis presented here leads to a new suggestion that clusters form by an analogue of the 'slingshot mechanism' previously proposed for stars.

  3. Numerical study of base pressure characteristic curve for a four-engine clustered nozzle configuration

    Science.gov (United States)

    Wang, Ten-See

    1993-07-01

    Excessive base heating has been a problem for many launch vehicles. For certain designs such as the direct dump of turbine exhaust in the nozzle section and at the nozzle lip of the Space Transportation Systems Engine (STME), the potential burning of the turbine exhaust in the base region has caused tremendous concern. Two conventional approaches have been considered for predicting the base environment: (1) empirical approach, and (2) experimental approach. The empirical approach uses a combination of data correlations and semi-theoretical calculations. It works best for linear problems, simple physics and geometry. However, it is highly suspicious when complex geometry and flow physics are involved, especially when the subject is out of historical database. The experimental approach is often used to establish database for engineering analysis. However, it is qualitative at best for base flow problems. Other criticisms include the inability to simulate forebody boundary layer correctly, the interference effect from tunnel walls, and the inability to scale all pertinent parameters. Furthermore, there is a contention that the information extrapolated from subscale tests with combustion is not conservative. One potential alternative to the conventional methods is computational fluid dynamics (CFD), which has none of the above restrictions and is becoming more feasible due to maturing algorithms and advancing computer technology. It provides more details of the flowfield and is only limited by computer resources. However, it has its share of criticisms as a predictive tool for base environment. One major concern is that CFD has not been extensively tested for base flow problems. It is therefore imperative that CFD be assessed and benchmarked satisfactorily for base flows. In this study, the turbulent base flowfield of a experimental investigation for a four-engine clustered nozzle is numerically benchmarked using a pressure based CFD method. Since the cold air was the

  4. Clustering multilayer omics data using MuNCut.

    Science.gov (United States)

    Teran Hidalgo, Sebastian J; Ma, Shuangge

    2018-03-14

    Omics profiling is now a routine component of biomedical studies. In the analysis of omics data, clustering is an essential step and serves multiple purposes including for example revealing the unknown functionalities of omics units, assisting dimension reduction in outcome model building, and others. In the most recent omics studies, a prominent trend is to conduct multilayer profiling, which collects multiple types of genetic, genomic, epigenetic and other measurements on the same subjects. In the literature, clustering methods tailored to multilayer omics data are still limited. Directly applying the existing clustering methods to multilayer omics data and clustering each layer first and then combing across layers are both "suboptimal" in that they do not accommodate the interconnections within layers and across layers in an informative way. In this study, we develop the MuNCut (Multilayer NCut) clustering approach. It is tailored to multilayer omics data and sufficiently accounts for both across- and within-layer connections. It is based on the novel NCut technique and also takes advantages of regularized sparse estimation. It has an intuitive formulation and is computationally very feasible. To facilitate implementation, we develop the function muncut in the R package NcutYX. Under a wide spectrum of simulation settings, it outperforms competitors. The analysis of TCGA (The Cancer Genome Atlas) data on breast cancer and cervical cancer shows that MuNCut generates biologically meaningful results which differ from those using the alternatives. We propose a more effective clustering analysis of multiple omics data. It provides a new venue for jointly analyzing genetic, genomic, epigenetic and other measurements.

  5. THE ASSEMBLY OF GALAXY CLUSTERS

    International Nuclear Information System (INIS)

    Berrier, Joel C.; Stewart, Kyle R.; Bullock, James S.; Purcell, Chris W.; Barton, Elizabeth J.; Wechsler, Risa H.

    2009-01-01

    We study the formation of 53 galaxy cluster-size dark matter halos (M = 10 14.0-14.76 M sun ) formed within a pair of cosmological Λ cold dark matter N-body simulations, and track the accretion histories of cluster subhalos with masses large enough to host ∼0.3 L * galaxies. By associating subhalos with cluster galaxies, we find the majority of galaxies in clusters experience no 'preprocessing' in the group environment prior to their accretion into the cluster. On average, 70% of cluster galaxies fall into the cluster potential directly from the field, with no luminous companions in their host halos at the time of accretion; less than 12% are accreted as members of groups with five or more galaxies. Moreover, we find that cluster galaxies are significantly less likely to have experienced a merger in the recent past (∼<6 Gyr) than a field halo of the same mass. These results suggest that local cluster processes such as ram pressure stripping, galaxy harassment, or strangulation play the dominant role in explaining the difference between cluster and field populations at a fixed stellar mass, and that pre-evolution or past merging in the group environment is of secondary importance for setting cluster galaxy properties for most clusters. The accretion times for z = 0 cluster members are quite extended, with ∼20% incorporated into the cluster halo more than 7 Gyr ago and ∼20% within the last 2 Gyr. By comparing the observed morphological fractions in cluster and field populations, we estimate an approximate timescale for late-type to early-type transformation within the cluster environment to be ∼6 Gyr.

  6. Dynamic airway pressure-time curve profile (Stress Index): a systematic review.

    Science.gov (United States)

    Terragni, Pierpaolo; Bussone, Guido; Mascia, Luciana

    2016-01-01

    The assessment of respiratory mechanics at the bedside is necessary in order to identify the most protective ventilatory strategy. Indeed in the last 20 years, adverse effects of positive ventilation to the lung structures have led to a reappraisal of the objectives of mechanical ventilation. The ventilator setting requires repeated readjustment over the period of mechanical ventilation dependency and careful respiratory monitoring to minimize the risks, preventing further injury and permitting the lung and airways healing. Among the different methods that have been proposed and validated, the analysis of dynamic P-t curve (named Stress Index, SI) represents an adequate tool available at the bedside, repeatable and, therefore, able to identify the amount of overdistension occurring in the daily clinical practice, when modifying positive end-expiratory pressure. In this review we will analyze the evidence that supports respiratory mechanics assessment at the bedside and the application of the dynamic P/t curve profile (SI) to optimize protective ventilation in patients with acute respiratory failure.

  7. Simulated X-ray galaxy clusters at the virial radius: Slopes of the gas density, temperature and surface brightness profiles

    Science.gov (United States)

    Roncarelli, M.; Ettori, S.; Dolag, K.; Moscardini, L.; Borgani, S.; Murante, G.

    2006-12-01

    Using a set of hydrodynamical simulations of nine galaxy clusters with masses in the range 1.5 × 1014 matter of tension between simulated and observed properties, and up to the virial radius and beyond, where present observations are unable to provide any constraints. We have modelled the radial profiles between 0.3R200 and 3R200 with power laws with one index, two indexes and a rolling index. The simulated temperature and [0.5-2] keV surface brightness profiles well reproduce the observed behaviours outside the core. The shape of all these profiles in the radial range considered depends mainly on the activity of the gravitational collapse, with no significant difference among models including extraphysics. The profiles steepen in the outskirts, with the slope of the power-law fit that changes from -2.5 to -3.4 in the gas density, from -0.5 to -1.8 in the gas temperature and from -3.5 to -5.0 in the X-ray soft surface brightness. We predict that the gas density, temperature and [0.5-2] keV surface brightness values at R200 are, on average, 0.05, 0.60, 0.008 times the measured values at 0.3R200. At 2R200, these values decrease by an order of magnitude in the gas density and surface brightness, by a factor of 2 in the temperature, putting stringent limits on the detectable properties of the intracluster-medium (ICM) in the virial regions.

  8. Effect of high pressure treatment on metabolite profile of marinated meat in soy sauce.

    Science.gov (United States)

    Yang, Yang; Ye, Yangfang; Wang, Ying; Sun, Yangying; Pan, Daodong; Cao, Jinxuan

    2018-02-01

    Marinated meat in soy sauce was produced using hind leg by washing, rubbing salt, marinating with soy sauce and spices, and air dry-ripening for 15d. The effect of high pressure (HP) (150 and 300MPa for 15min) on the metabolite profiles of products was characterized using 1 H NMR and multivariate data analysis. The results showed that the metabonome was dominated by 26 metabolites, including amino acids, sugars, organic acids, nucleic aides and their derivatives. PC1 and PC2 explained a total of 75.4 and 11.9% of variables, respectively. HP treatments increased most of the metabolites, especially PC1, glutamate, sugars, nucleotides, anserine, lactate and creatine compared to the control. The increase of metabolites under HP was not dependent on pressure level except for alanine, lactate, acetate, formate, fumarate, glucose and 5'-IMP. These findings demonstrated that HP treatment at 150MPa was economical to improve the taste of marinated meat in soy sauce. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Associations of Streptococcus suis serotype 2 ribotype profiles with clinical disease and antimicrobial resistance

    DEFF Research Database (Denmark)

    Rasmussen, S. R.; Aarestrup, Frank Møller; Jensen, N. E.

    1999-01-01

    A total of 122 Streptococcus suis serotype 2 strains were characterized thoroughly by comparing clinical and pathological observations, ribotype profiles, and antimicrobial resistance. Twenty-one different ribotype profiles were found and compared by cluster analysis, resulting in the identificat......A total of 122 Streptococcus suis serotype 2 strains were characterized thoroughly by comparing clinical and pathological observations, ribotype profiles, and antimicrobial resistance. Twenty-one different ribotype profiles were found and compared by cluster analysis, resulting...

  10. The Cosmological Dependence of Galaxy Cluster Morphologies

    Science.gov (United States)

    Crone, Mary Margaret

    1995-01-01

    Measuring the density of the universe has been a fundamental problem in cosmology ever since the "Big Bang" model was developed over sixty years ago. In this simple and successful model, the age and eventual fate of the universe are determined by its density, its rate of expansion, and the value of a universal "cosmological constant". Analytic models suggest that many properties of galaxy clusters are sensitive to cosmological parameters. In this thesis, I use N-body simulations to examine cluster density profiles, abundances, and degree of subclustering to test the feasibility of using them as cosmological tests. The dependence on both cosmology and initial density field is examined, using a grid of cosmologies and scale-free initial power spectra P(k)~ k n. Einstein-deSitter ( Omegao=1), open ( Omegao=0.2 and 0.1) and flat, low density (Omegao=0.2, lambdao=0.8) models are studied, with initial spectral indices n=-2, -1 and 0. Of particular interest are the results for cluster profiles and substructure. The average density profiles are well fit by a power law p(r)~ r ^{-alpha} for radii where the local density contrast is between 100 and 3000. There is a clear trend toward steeper slopes with both increasing n and decreasing Omegao, with profile slopes in the open models consistently higher than Omega=1 values for the range of n examined. The amount of substructure in each model is quantified and explained in terms of cluster merger histories and the behavior of substructure statistics. The statistic which best distinguishes models is a very simple measure of deviations from symmetry in the projected mass distribution --the "Center-of-Mass Shift" as a function of overdensity. Some statistics which are quite sensitive to substructure perform relatively poorly as cosmological indicators. Density profiles and the Center-of-Mass test are both well-suited for comparison with weak lensing data and galaxy distributions. Such data are currently being collected and should

  11. The Atacama Cosmology Telescope (ACT): Beam Profiles and First SZ Cluster Maps

    Science.gov (United States)

    Hincks, A. D.; Acquaviva, V.; Ade, P. A.; Aguirre, P.; Amiri, M.; Appel, J. W.; Barrientos, L. F.; Battistelli, E. S.; Bond, J. R.; Brown, B.; hide

    2010-01-01

    The Atacama Cosmology Telescope (ACT) is currently observing the cosmic microwave background with arcminute resolution at 148 GHz, 218 GHz, and 277 GHz, In this paper, we present ACT's first results. Data have been analyzed using a maximum-likelihood map-making method which uses B-splines to model and remove the atmospheric signal. It has been used to make high-precision beam maps from which we determine the experiment's window functions, This beam information directly impacts all subsequent analyses of the data. We also used the method to map a sample of galaxy clusters via the Sunyaev-Ze1'dovich (SZ) effect, and show five clusters previously detected with X-ray or SZ observations, We provide integrated Compton-y measurements for each cluster. Of particular interest is our detection of the z = 0.44 component of A3128 and our current non-detection of the low-redshift part, providing strong evidence that the further cluster is more massive as suggested by X-ray measurements. This is a compelling example of the redshift-independent mass selection of the SZ effect.

  12. INDICATORS FOR CLUSTER SURVIVABILITY IN A DISPERSING CLOUD

    International Nuclear Information System (INIS)

    Chen, H.-C.; Ko, C.-M.

    2009-01-01

    We use N-body simulations to survey the response of embedded star clusters to the dispersal of their parent molecular cloud. The final stages of the clusters can be divided into three classes: the cluster (1) is destroyed, (2) has a loose structure, and (3) has a compact core. We are interested in three of the governing parameters of the parent cloud: (1) the mass, (2) the size, and (3) the dispersing rate. It is known that the final stage of the cluster is well correlated with the star formation efficiency (SFE) for systems with the same cluster and cloud profile. We deem that the SFE alone is not enough to address systems with clouds of different sizes. Our result shows that the initial cluster-cloud mass ratio at a certain Lagrangian radius and the initial kinetic energy are better indicators for the survivability of embedded clusters.

  13. The Most Massive Star Clusters: Supermassive Globular Clusters or Dwarf Galaxy Nuclei?

    Science.gov (United States)

    Harris, William

    2004-07-01

    Evidence is mounting that the most massive globular clusters, such as Omega Centauri and M31-G1, may be related to the recently discovered "Ultra-Compact Dwarfs" and the dense nuclei of dE, N galaxies. However, no systematic imaging investigation of these supermassive globular clusters - at the level of Omega Cen and beyond - has been done, and we do not know what fraction of them might bear the signatures {such as large effective radii or tidal tails} of having originated as dE nuclei. We propose to use the ACS/WFC to obtain deep images of 18 such clusters in NGC 5128 and M31, the two nearest rich globular cluster systems. These globulars are the richest star clusters that can be found in nature, the biggest of them reaching 10^7 Solar masses, and they are likely to represent the results of star formation under the densest and most extreme conditions known. Using the profiles of the clusters including their faint outer envelopes, we will carry out state-of-the-art dynamical modelling of their structures, and look for any clear evidence which would indicate that they are associated with stripped satellites. This study will build on our previous work with STIS and WFPC2 imaging designed to study the 'Fundamental Plane' of globular clusters. When our new work is combined with Archival WFPC2, STIS, and ACS material, we will also be able to construct the definitive mapping of the Fundamental Plane of globular clusters at its uppermost mass range, and confirm whether or not the UCD and dE, N objects occupy a different structural parameter space.

  14. Is the Coma cluster binary dominated?

    International Nuclear Information System (INIS)

    The, L.S.; White, S.D.M.

    1990-01-01

    It is investigated whether the model of an expanding cluster dominated by a massive binary galaxy, first suggested by Valtonen and Byrd (1979), is consistent with optical data on the surface density and velocity dispersion of the Coma cluster. The evolution of this model is simulated for a wide variety of initial conditions. It is found that galaxy counts in the model can be made to agree with observation, but that the observed velocity dispersion profile cannot be reproduced. A number of other arguments suggest that the central galaxies in Coma cannot be as massive as required by the model. This model is not a viable representation of the Coma cluster. 25 refs

  15. Blood pressure and antihypertensive medication profile in a multiethnic Asian population of stable chronic kidney disease patients.

    Science.gov (United States)

    Teo, Boon Wee; Chua, Horng Ruey; Wong, Weng Kin; Haroon, Sabrina; Subramanian, Srinivas; Loh, Ping Tyug; Sethi, Sunil; Lau, Titus

    2016-05-01

    Clinical practice guidelines recommend different blood pressure (BP) goals for chronic kidney disease (CKD) patients. Usage of antihypertensive medication and attainment of BP targets in Asian CKD patients remain unclear. This study describes the profile of antihypertensive agents used and BP components in a multiethnic Asian population with stable CKD. Stable CKD outpatients with variability of serum creatinine levels 3 months apart, were recruited. Mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured using automated manometers, according to practice guidelines. Serum creatinine was assayed and the estimated glomerular filtration rate (GFR) calculated using the CKD Epidemiology Collaboration equation. BP and antihypertensive medication profile was examined using univariate analyses. 613 patients (55.1% male; 74.7% Chinese, 6.4% Indian, 11.4% Malay; 35.7% diabetes mellitus) with a mean age of 57.8 ± 14.5 years were recruited. Mean SBP was 139 ± 20 mmHg, DBP was 74 ± 11 mmHg, serum creatinine was 166 ± 115 µmol/L and GFR was 53 ± 32 mL/min/1.73 m(2). At a lower GFR, SBP increased (p < 0.001), whereas DBP decreased (p = 0.0052). Mean SBP increased in tandem with the number of antihypertensive agents used (p < 0.001), while mean DBP decreased when ≥ 3 antihypertensive agents were used (p = 0.0020). Different targets are recommended for each BP component in CKD patients. A majority of patients cannot attain SBP targets and/or exceed DBP targets. Research into monitoring and treatment methods is required to better define BP targets in CKD patients. Copyright: © Singapore Medical Association.

  16. Density structures inside the plasmasphere: Cluster observations

    DEFF Research Database (Denmark)

    Darrouzet, F.; Decreau, P.M.E.; De Keyser, J.

    2004-01-01

    The electron density profiles derived from the EFW and WHISPER instruments on board the four Cluster spacecraft reveal density structures inside the plasmasphere and at its outer boundary, the plasmapause. We have conducted a statistical study to characterize these density structures. We focus...... on the plasmasphere crossing on I I April 2002, during which Cluster observed several density irregularities inside the plasmasphere, as well as a plasmaspheric plume. We derive the density gradient vectors from simultaneous density measurements by the four spacecraft. We also determine the normal velocity...... of the boundaries of the plume and of the irregularities from the time delays between those boundaries in the four individual density profiles, assuming they are planar. These new observations yield novel insights about the occurrence of density irregularities, their geometry and their dynamics. These in...

  17. Study of flow profile distortions and efficiency in counter pressure moderated partial filling micellar electrokinetic chromatography in relation to the relative buffer zone lengths.

    Science.gov (United States)

    Michalke, Daniela; Welsch, Thomas

    2002-06-25

    The influence of the relative buffer zone lengths on the efficiency was investigated in partial filling micellar electrokinetic chromatography using sodium dodecyl sulfate as separation additive. Varying relative zone lengths were obtained by applying identical initial separation zone lengths but different total lengths of the capillaries. Plate numbers of a homologous series of omega-phenylalcohols were measured to indicate the effect of both a changing relative zone length during the run and a counter pressure applied on the cathodic buffer reservoir. The magnitude and the course of these plate numbers are discussed on the basis of models for flow profile superposition and flow profile deformation which are caused by an intersegmental pressure arising at the boundary between the two buffer zones with different electroosmotic flow velocities. Calculation of the intersegmental pressure and of the resulting laminar flow components in the buffer zones on the basis of some equations for electroosmotic and hydrodynamic flow supported the interpretation that a long background buffer zone should be avoided

  18. High-pressure system for Compton scattering experiments

    International Nuclear Information System (INIS)

    Oomi, G.; Honda, F.; Kagayama, T.; Itoh, F.; Sakurai, H.; Kawata, H.; Shimomura, O.

    1998-01-01

    High-pressure apparatus for Compton scattering experiments has been developed to study the momentum distribution of conduction electrons in metals and alloys at high pressure. This apparatus was applied to observe the Compton profile of metallic Li under pressure. It was found that the Compton profile at high pressure could be obtained within several hours by using this apparatus and synchrotron radiation. The result on the pressure dependence of the Fermi momentum of Li obtained here is in good agreement with that predicted from the free-electron model

  19. Rod cluster having improved vane configuration

    International Nuclear Information System (INIS)

    Shockling, L.A.; Francis, T.A.

    1989-01-01

    This patent describes a pressurized water reactor vessel, the vessel defining a predetermined axial direction of the flow of coolant therewithin and having plural spider assemblies supporting, for vertical movement within the vessel, respective clusters of rods in spaced, parallel axial relationship, parallel to the predetermined axial direction of coolant flow, and a rod guide for each spider assembly and respective cluster of rods. The rod guide having horizontally oriented support plates therewithin, each plate having an interior opening for accommodating axial movement therethrough of the spider assembly and respective cluster of rods. The opening defining plural radially extending channels and corresponding parallel interior wall surfaces of the support plate

  20. The effect of mining data k-means clustering toward students profile model drop out potential

    Science.gov (United States)

    Purba, Windania; Tamba, Saut; Saragih, Jepronel

    2018-04-01

    The high of student success and the low of student failure can reflect the quality of a college. One of the factors of fail students was drop out. To solve the problem, so mining data with K-means Clustering was applied. K-Means Clustering method would be implemented to clustering the drop out students potentially. Firstly the the result data would be clustering to get the information of all students condition. Based on the model taken was found that students who potentially drop out because of the unexciting students in learning, unsupported parents, diffident students and less of students behavior time. The result of process of K-Means Clustering could known that students who more potentially drop out were in Cluster 1 caused Credit Total System, Quality Total, and the lowest Grade Point Average (GPA) compared between cluster 2 and 3.

  1. A WARM MOLECULAR HYDROGEN TAIL DUE TO RAM-PRESSURE STRIPPING OF A CLUSTER GALAXY

    International Nuclear Information System (INIS)

    Sivanandam, Suresh; Rieke, Marcia J.; Rieke, George H.

    2010-01-01

    We have discovered a remarkable warm (130-160 K) molecular hydrogen tail with a H 2 mass of approximately 4 x 10 7 M sun extending 20 kpc from a cluster spiral galaxy, ESO 137-001, in Abell 3627. At least half of this gas is lost permanently to the intracluster medium, as the tail extends beyond the tidal radius of the galaxy. We also detect a hot (400-550 K) component in the tail that is approximately 1% of the mass. The large H 2 line to IR continuum luminosity ratio in the tail indicates that star formation is not a major excitation source and that the gas is possibly shock-heated. This discovery confirms that the galaxy is currently undergoing ram-pressure stripping, as also indicated by its previously discovered X-ray and Hα tails. We estimate that the galaxy is losing its warm H 2 gas at a rate of ∼2-3 M sun yr -1 . The true mass-loss rate is likely higher if we account for cold molecular gas and atomic gas. We predict that the galaxy will lose most of its gas in a single pass through the core and place a strong upper limit on the ram-pressure timescale of 1 Gyr. We also study the star-forming properties of the galaxy and its tail. We identify most of the previously discovered external Hα sources within the tail in our 8 μm data but not in our 3.6 μm data; IRS spectroscopy of the region containing these Hα sources also reveals aromatic features typically associated with star formation. From the positions of these H II regions, it appears that star formation is not occurring throughout the molecular hydrogen tail but only immediately downstream of the galaxy. Some of these H II regions lie outside the tidal radius of the galaxy, indicating that ram-pressure stripping can be a source of intracluster stars.

  2. Impaired Fasting Glucose in Nondiabetic Range: Is It a Marker of Cardiovascular Risk Factor Clustering?

    Directory of Open Access Journals (Sweden)

    Giovanna Valentino

    2015-01-01

    Full Text Available Background. Impaired fasting glucose (IFG through the nondiabetic range (100–125 mg/dL is not considered in the cardiovascular (CV risk profile. Aim. To compare the clustering of CV risk factors (RFs in nondiabetic subjects with normal fasting glucose (NFG and IFG. Material and Methods. Cross-sectional study in 3739 nondiabetic subjects. Demographics, medical history, and CV risk factors were collected and lipid profile, fasting glucose levels (FBG, C-reactive protein (hsCRP, blood pressure (BP, anthropometric measurements, and aerobic capacity were determined. Results. 559 (15% subjects had IFG: they had a higher mean age, BMI, waist circumference, non-HDL cholesterol, BP, and hsCRP (p<0.0001 and lower HDL (p<0.001 and aerobic capacity (p<0.001. They also had a higher prevalence of hypertension (34% versus 25%; p<0.001, dyslipidemia (79% versus 74%; p<0.001, and obesity (29% versus 16%; p<0.001 and a higher Framingham risk score (8% versus 6%; p<0.001. The probability of presenting 3 or more CV RFs adjusted by age and gender was significantly higher in the top quintile of fasting glucose (≥98 mg/dL; OR = 2.02; 1.62–2.51. Conclusions. IFG in the nondiabetic range is associated with increased cardiovascular RF clustering.

  3. Simulating The Dynamical Evolution Of Galaxies In Group And Cluster Environments

    Science.gov (United States)

    Vijayaraghavan, Rukmani

    2015-07-01

    Galaxy clusters are harsh environments for their constituent galaxies. A variety of physical processes effective in these dense environments transform gas-rich, spiral, star-forming galaxies to elliptical or spheroidal galaxies with very little gas and therefore minimal star formation. The consequences of these processes are well understood observationally. Galaxies in progressively denser environments have systematically declining star formation rates and gas content. However, a theoretical understanding of of where, when, and how these processes act, and the interplay between the various galaxy transformation mechanisms in clusters remains elusive. In this dissertation, I use numerical simulations of cluster mergers as well as galaxies evolving in quiescent environments to develop a theoretical framework to understand some of the physics of galaxy transformation in cluster environments. Galaxies can be transformed in smaller groups before they are accreted by their eventual massive cluster environments, an effect termed `pre-processing'. Galaxy cluster mergers themselves can accelerate many galaxy transformation mechanisms, including tidal and ram pressure stripping of galaxies and galaxy-galaxy collisions and mergers that result in reassemblies of galaxies' stars and gas. Observationally, cluster mergers have distinct velocity and phase-space signatures depending on the observer's line of sight with respect to the merger direction. Using dark matter only as well as hydrodynamic simulations of cluster mergers with random ensembles of particles tagged with galaxy models, I quantify the effects of cluster mergers on galaxy evolution before, during, and after the mergers. Based on my theoretical predictions of the dynamical signatures of these mergers in combination with galaxy transformation signatures, one can observationally identify remnants of mergers and quantify the effect of the environment on galaxies in dense group and cluster environments. The presence of

  4. Prioritizing the risk of plant pests by clustering methods; self-organising maps, k-means and hierarchical clustering

    Directory of Open Access Journals (Sweden)

    Susan Worner

    2013-09-01

    Full Text Available For greater preparedness, pest risk assessors are required to prioritise long lists of pest species with potential to establish and cause significant impact in an endangered area. Such prioritization is often qualitative, subjective, and sometimes biased, relying mostly on expert and stakeholder consultation. In recent years, cluster based analyses have been used to investigate regional pest species assemblages or pest profiles to indicate the risk of new organism establishment. Such an approach is based on the premise that the co-occurrence of well-known global invasive pest species in a region is not random, and that the pest species profile or assemblage integrates complex functional relationships that are difficult to tease apart. In other words, the assemblage can help identify and prioritise species that pose a threat in a target region. A computational intelligence method called a Kohonen self-organizing map (SOM, a type of artificial neural network, was the first clustering method applied to analyse assemblages of invasive pests. The SOM is a well known dimension reduction and visualization method especially useful for high dimensional data that more conventional clustering methods may not analyse suitably. Like all clustering algorithms, the SOM can give details of clusters that identify regions with similar pest assemblages, possible donor and recipient regions. More important, however SOM connection weights that result from the analysis can be used to rank the strength of association of each species within each regional assemblage. Species with high weights that are not already established in the target region are identified as high risk. However, the SOM analysis is only the first step in a process to assess risk to be used alongside or incorporated within other measures. Here we illustrate the application of SOM analyses in a range of contexts in invasive species risk assessment, and discuss other clustering methods such as k

  5. Personalized Profile Based Search Interface With Ranked and Clustered Display

    National Research Council Canada - National Science Library

    Kumar, Sachin; Oztekin, B. U; Ertoz, Levent; Singhal, Saurabh; Han, Euihong; Kumar, Vipin

    2001-01-01

    We have developed an experimental meta-search engine, which takes the snippets from traditional search engines and presents them to the user either in the form of clusters, indices or re-ranked list...

  6. OSO 8 X-ray spectra of clusters of galaxies. I - Observations of twenty clusters: Physical correlations

    Science.gov (United States)

    Mushotzky, R. F.; Serlemitsos, P. J.; Boldt, E. A.; Holt, S. S.; Smith, B. W.

    1978-01-01

    OSO 8 X-ray spectra from 2 to 20 keV have been analyzed for 26 clusters of galaxies. For 20 clusters temperatures, emission integrals, iron abundances, and low-energy absorption measurements are presented. The data give, in general, better fits to thermal bremsstrahlung than to power-law models. Eight clusters have positive iron emission-line detections at the 90% confidence level, and all 20 cluster spectra are consistent with Fe/H = 0.000014 by number with the possible exception of Virgo. Thus it is confirmed that X-ray emission in this energy band is predominantly thermal radiation from hot intracluster gas rather than inverse Compton radiation. Physical correlations between X-ray spectral parameters and other cluster properties are examined. It is found that (1) the X-ray temperature is approximately proportional to the square of the velocity dispersion of the galaxies; (2) the emission integral is a strong function of the X-ray temperature; (3) the X-ray temperature and emission integral are better correlated with cluster central-galaxy density than with richness; and (4) the fraction of galaxies which are spirals is correlated with the observed ram pressure in the cluster core.

  7. Effect of tidal fields on star clusters

    Science.gov (United States)

    Chernoff, David; Weinberg, Martin

    1991-01-01

    We follow the dynamical evolution of a star cluster in a galactic tidal field using a restricted N-body code. We find large asymmetric distortions in the outer profile of the cluster in the first 10 or so crossing times as material is lost. Prograde stars escape preferentially and establish a potentially observable retrograde rotation in the halo. We present the rate of particle loss and compare with the prescription proposed by Lee and Ostriker (1987).

  8. Detection of CO emission in Hydra 1 cluster galaxies

    International Nuclear Information System (INIS)

    Huchtmeier, W.K.

    1990-01-01

    A survey of bright Hydra cluster spiral galaxies for the CO(1-0) transition at 115 GHz was performed with the 15m Swedish-ESO submillimeter telescope (SEST). Five out of 15 galaxies observed have been detected in the CO(1-0) line. The largest spiral galaxy in the cluster, NGC 3312, got more CO than any spiral of the Virgo cluster. This Sa-type galaxy is optically largely distorted and disrupted on one side. It is a good candidate for ram pressure stripping while passing through the cluster's central region. A comparison with global CO properties of Virgo cluster spirals shows a relatively good agreement with the detected Hydra cluster galaxies

  9. THE HST/ACS COMA CLUSTER SURVEY. IV. INTERGALACTIC GLOBULAR CLUSTERS AND THE MASSIVE GLOBULAR CLUSTER SYSTEM AT THE CORE OF THE COMA GALAXY CLUSTER

    International Nuclear Information System (INIS)

    Peng, Eric W.; Ferguson, Henry C.; Goudfrooij, Paul; Hammer, Derek; Lucey, John R.; Marzke, Ronald O.; Puzia, Thomas H.; Carter, David; Balcells, Marc; Bridges, Terry; Chiboucas, Kristin; Del Burgo, Carlos; Graham, Alister W.; Guzman, Rafael; Hudson, Michael J.; Matkovic, Ana

    2011-01-01

    Intracluster stellar populations are a natural result of tidal interactions in galaxy clusters. Measuring these populations is difficult, but important for understanding the assembly of the most massive galaxies. The Coma cluster of galaxies is one of the nearest truly massive galaxy clusters and is host to a correspondingly large system of globular clusters (GCs). We use imaging from the HST/ACS Coma Cluster Survey to present the first definitive detection of a large population of intracluster GCs (IGCs) that fills the Coma cluster core and is not associated with individual galaxies. The GC surface density profile around the central massive elliptical galaxy, NGC 4874, is dominated at large radii by a population of IGCs that extend to the limit of our data (R +4000 -5000 (systematic) IGCs out to this radius, and that they make up ∼70% of the central GC system, making this the largest GC system in the nearby universe. Even including the GC systems of other cluster galaxies, the IGCs still make up ∼30%-45% of the GCs in the cluster core. Observational limits from previous studies of the intracluster light (ICL) suggest that the IGC population has a high specific frequency. If the IGC population has a specific frequency similar to high-S N dwarf galaxies, then the ICL has a mean surface brightness of μ V ∼ 27 mag arcsec -2 and a total stellar mass of roughly 10 12 M sun within the cluster core. The ICL makes up approximately half of the stellar luminosity and one-third of the stellar mass of the central (NGC 4874+ICL) system. The color distribution of the IGC population is bimodal, with blue, metal-poor GCs outnumbering red, metal-rich GCs by a ratio of 4:1. The inner GCs associated with NGC 4874 also have a bimodal distribution in color, but with a redder metal-poor population. The fraction of red IGCs (20%), and the red color of those GCs, implies that IGCs can originate from the halos of relatively massive, L* galaxies, and not solely from the disruption of

  10. Temperature profile, pressure, and nutrients data from bottle in South Atlantic Ocean from 24 November 1987 to 12 March 1989 (NODC Accession 0000196)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile, pressure, and nutrients data were collected using bottle in the South Atlantic Ocean from 24 November 1987 to 12 March 1989. Data were collected...

  11. EVOLUTION OF THE MERGER-INDUCED HYDROSTATIC MASS BIAS IN GALAXY CLUSTERS

    International Nuclear Information System (INIS)

    Nelson, Kaylea; Nagai, Daisuke; Rudd, Douglas H.; Shaw, Laurie

    2012-01-01

    In this work, we examine the effects of mergers on the hydrostatic mass estimate of galaxy clusters using high-resolution Eulerian cosmological simulations. We utilize merger trees to isolate the last merger for each cluster in our sample and follow the time evolution of the hydrostatic mass bias as the systems relax. We find that during a merger, a shock propagates outward from the parent cluster, resulting in an overestimate in the hydrostatic mass bias. After the merger, as a cluster relaxes, the bias in hydrostatic mass estimate decreases but remains at a level of –5%-10% with 15%-20% scatter within r 500 . We also investigate the post-merger evolution of the pressure support from bulk motions, a dominant cause of this residual mass bias. At r 500 , the contribution from random motions peaks at 30% of the total pressure during the merger and quickly decays to ∼10%-15% as a cluster relaxes. Additionally, we use a measure of the random motion pressure to correct the hydrostatic mass estimate. We discover that 4 Gyr after mergers, the direct effects of the merger event on the hydrostatic mass bias have become negligible. Thereafter, the mass bias is primarily due to residual bulk motions in the gas which are not accounted for in the hydrostatic equilibrium equation. We present a hydrostatic mass bias correction method that can recover the unbiased cluster mass for relaxed clusters with 9% scatter at r 500 and 11% scatter in the outskirts, within r 200 .

  12. Detonation of Meta-stable Clusters

    Energy Technology Data Exchange (ETDEWEB)

    Kuhl, Allen; Kuhl, Allen L.; Fried, Laurence E.; Howard, W. Michael; Seizew, Michael R.; Bell, John B.; Beckner, Vincent; Grcar, Joseph F.

    2008-05-31

    We consider the energy accumulation in meta-stable clusters. This energy can be much larger than the typical chemical bond energy (~;;1 ev/atom). For example, polymeric nitrogen can accumulate 4 ev/atom in the N8 (fcc) structure, while helium can accumulate 9 ev/atom in the excited triplet state He2* . They release their energy by cluster fission: N8 -> 4N2 and He2* -> 2He. We study the locus of states in thermodynamic state space for the detonation of such meta-stable clusters. In particular, the equilibrium isentrope, starting at the Chapman-Jouguet state, and expanding down to 1 atmosphere was calculated with the Cheetah code. Large detonation pressures (3 and 16 Mbar), temperatures (12 and 34 kilo-K) and velocities (20 and 43 km/s) are a consequence of the large heats of detonation (6.6 and 50 kilo-cal/g) for nitrogen and helium clusters respectively. If such meta-stable clusters could be synthesized, they offer the potential for large increases in the energy density of materials.

  13. Metabolic Profiling of Alpine and Ecuadorian Lichens

    Directory of Open Access Journals (Sweden)

    Verena K. Mittermeier

    2015-10-01

    Full Text Available Non-targeted 1H-NMR methods were used to determine metabolite profiles from crude extracts of Alpine and Ecuadorian lichens collected from their natural habitats. In control experiments, the robustness of metabolite detection and quantification was estimated using replicate measurements of Stereocaulon alpinum extracts. The deviations in the overall metabolite fingerprints were low when analyzing S. alpinum collections from different locations or during different annual and seasonal periods. In contrast, metabolite profiles observed from extracts of different Alpine and Ecuadorian lichens clearly revealed genus- and species-specific profiles. The discriminating functions determining cluster formation in principle component analysis (PCA were due to differences in the amounts of genus-specific compounds such as sticticin from the Sticta species, but also in the amounts of ubiquitous metabolites, such as sugar alcohols or trehalose. However, varying concentrations of these metabolites from the same lichen species e.g., due to different environmental conditions appeared of minor relevance for the overall cluster formation in PCA. The metabolic clusters matched phylogenetic analyses using nuclear ribosomal DNA (nrDNA internal transcribed spacer (ITS sequences of lichen mycobionts, as exemplified for the genus Sticta. It can be concluded that NMR-based non-targeted metabolic profiling is a useful tool in the chemo-taxonomy of lichens. The same approach could also facilitate the discovery of novel lichen metabolites on a rapid and systematical basis.

  14. Intra Cluster Light properties in the CLASH-VLT cluster MACS J1206.2-0847

    CERN Document Server

    Presotto, V; Nonino, M; Mercurio, A; Grillo, C; Rosati, P; Biviano, A; Annunziatella, M; Balestra, I; Cui, W; Sartoris, B; Lemze, D; Ascaso, B; Moustakas, J; Ford, H; Fritz, A; Czoske, O; Ettori, S; Kuchner, U; Lombardi, M; Maier, C; Medezinski, E; Molino, A; Scodeggio, M; Strazzullo, V; Tozzi, P; Ziegler, B; Bartelmann, M; Benitez, N; Bradley, L; Brescia, M; Broadhurst, T; Coe, D; Donahue, M; Gobat, R; Graves, G; Kelson, D; Koekemoer, A; Melchior, P; Meneghetti, M; Merten, J; Moustakas, L; Munari, E; Postman, M; Regős, E; Seitz, S; Umetsu, K; Zheng, W; Zitrin, A

    2014-01-01

    We aim at constraining the assembly history of clusters by studying the intra cluster light (ICL) properties, estimating its contribution to the fraction of baryons in stars, f*, and understanding possible systematics/bias using different ICL detection techniques. We developed an automated method, GALtoICL, based on the software GALAPAGOS to obtain a refined version of typical BCG+ICL maps. We applied this method to our test case MACS J1206.2-0847, a massive cluster located at z=0.44, that is part of the CLASH sample. Using deep multi-band SUBARU images, we extracted the surface brightness (SB) profile of the BCG+ICL and we studied the ICL morphology, color, and contribution to f* out to R500. We repeated the same analysis using a different definition of the ICL, SBlimit method, i.e. a SB cut-off level, to compare the results. The most peculiar feature of the ICL in MACS1206 is its asymmetric radial distribution, with an excess in the SE direction and extending towards the 2nd brightest cluster galaxy which i...

  15. GOAL PROFILES, MENTAL TOUGHNESS AND ITS INFLUENCE ON PERFORMANCE OUTCOMES AMONG WUSHU ATHLETES

    Directory of Open Access Journals (Sweden)

    Garry Kuan

    2007-10-01

    Full Text Available This study examined the association between goal orientations and mental toughness and its influence on performance outcomes in competition. Wushu athletes (n = 40 competing in Intervarsity championships in Malaysia completed Task and Ego Orientations in Sport Questionnaire (TEOSQ and Psychological Performance Inventory (PPI. Using cluster analysis techniques including hierarchical methods and the non-hierarchical method (k-means cluster to examine goal profiles, a three cluster solution emerged viz. cluster 1 - high task and moderate ego (HT/ME, cluster 2 - moderate task and low ego (MT/LE and, cluster 3 - moderate task and moderate ego (MT/ME. Analysis of the fundamental areas of mental toughness based on goal profiles revealed that athletes in cluster 1 scored significantly higher on negative energy control than athletes in cluster 2. Further, athletes in cluster 1 also scored significantly higher on positive energy control than athletes in cluster 3. Chi-square (χ2 test revealed no significant differences among athletes with different goal profiles on performance outcomes in the competition. However, significant differences were observed between athletes (medallist and non medallist in self- confidence (p = 0.001 and negative energy control (p = 0.042. Medallist's scored significantly higher on self-confidence (mean = 21.82 ± 2.72 and negative energy control (mean = 19.59 ± 2.32 than the non-medallists (self confidence-mean = 18.76 ± 2.49; negative energy control mean = 18.14 ± 1.91.

  16. LoCuSS: weak-lensing mass calibration of galaxy clusters

    Science.gov (United States)

    Okabe, Nobuhiro; Smith, Graham P.

    2016-10-01

    We present weak-lensing mass measurements of 50 X-ray luminous galaxy clusters at 0.15 ≤ z ≤ 0.3, based on uniform high-quality observations with Suprime-Cam mounted on the 8.2-m Subaru telescope. We pay close attention to possible systematic biases, aiming to control them at the ≲4 per cent level. The dominant source of systematic bias in weak-lensing measurements of the mass of individual galaxy clusters is contamination of background galaxy catalogues by faint cluster and foreground galaxies. We extend our conservative method for selecting background galaxies with (V - I') colours redder than the red sequence of cluster members to use a colour-cut that depends on cluster-centric radius. This allows us to define background galaxy samples that suffer ≤1 per cent contamination, and comprise 13 galaxies per square arcminute. Thanks to the purity of our background galaxy catalogue, the largest systematic that we identify in our analysis is a shape measurement bias of 3 per cent, that we measure using simulations that probe weak shears up to g = 0.3. Our individual cluster mass and concentration measurements are in excellent agreement with predictions of the mass-concentration relation. Equally, our stacked shear profile is in excellent agreement with the Navarro Frenk and White profile. Our new Local Cluster Substructure Survey mass measurements are consistent with the Canadian Cluster Cosmology Project and Cluster Lensing And Supernova Survey with Hubble surveys, and in tension with the Weighing the Giants at ˜1σ-2σ significance. Overall, the consensus at z ≤ 0.3 that is emerging from these complementary surveys represents important progress for cluster mass calibration, and augurs well for cluster cosmology.

  17. Interacting star clusters in the Large Magellanic Cloud. Overmerging problem solved by cluster group formation

    Science.gov (United States)

    Leon, Stéphane; Bergond, Gilles; Vallenari, Antonella

    1999-04-01

    We present the tidal tail distributions of a sample of candidate binary clusters located in the bar of the Large Magellanic Cloud (LMC). One isolated cluster, SL 268, is presented in order to study the effect of the LMC tidal field. All the candidate binary clusters show tidal tails, confirming that the pairs are formed by physically linked objects. The stellar mass in the tails covers a large range, from 1.8x 10(3) to 3x 10(4) \\msun. We derive a total mass estimate for SL 268 and SL 356. At large radii, the projected density profiles of SL 268 and SL 356 fall off as r(-gamma ) , with gamma = 2.27 and gamma =3.44, respectively. Out of 4 pairs or multiple systems, 2 are older than the theoretical survival time of binary clusters (going from a few 10(6) years to 10(8) years). A pair shows too large age difference between the components to be consistent with classical theoretical models of binary cluster formation (Fujimoto & Kumai \\cite{fujimoto97}). We refer to this as the ``overmerging'' problem. A different scenario is proposed: the formation proceeds in large molecular complexes giving birth to groups of clusters over a few 10(7) years. In these groups the expected cluster encounter rate is larger, and tidal capture has higher probability. Cluster pairs are not born together through the splitting of the parent cloud, but formed later by tidal capture. For 3 pairs, we tentatively identify the star cluster group (SCG) memberships. The SCG formation, through the recent cluster starburst triggered by the LMC-SMC encounter, in contrast with the quiescent open cluster formation in the Milky Way can be an explanation to the paucity of binary clusters observed in our Galaxy. Based on observations collected at the European Southern Observatory, La Silla, Chile}

  18. Multiply imaged Transient Events in Cluster Lenses

    Science.gov (United States)

    Narasimha, Delampady

    2018-04-01

    ARIES had a successful gravitational microlens project during 1998-2002. A similar monitor for Transient Events in galaxies at high redshift lensed by rich galaxy-clusters provides a challenging possibility with important cosmological implications. Rich galaxy-clusters at intermediate redshifts are powerful gravitational lenses which produce multiple images, in the shape of giant arcs of 5-20" extent, of distant background galaxies in their field. Weak lens shear of the background galaxy distribution can reliably trace the lens mass profile. Multiple images of supernovae or GRBs in the background galaxies can be recorded in a systematic monitor of the system. An unlensed high redshift supernova might not be observable, but when lensed by a galaxy-cluster, it will stand out because the point event brightens relative to the host. The color profile of a high redshift lensed point event will be much more reliable than an unlensed one due to much less host contamination. An estimate of the time delay enables observation of the full light curve of the subsequent images of the event. ARIES can have outside collaboration for multiband simultaneous lightcurves of other images. The measured time delay and position of images of the transient event provide better cosmological constraints including distance scale of the Universe. The Devasthal telescope can detect one or more events by monitoring half a dozen cluster fields over three years time.

  19. Clustering of near clusters versus cluster compactness

    International Nuclear Information System (INIS)

    Yu Gao; Yipeng Jing

    1989-01-01

    The clustering properties of near Zwicky clusters are studied by using the two-point angular correlation function. The angular correlation functions for compact and medium compact clusters, for open clusters, and for all near Zwicky clusters are estimated. The results show much stronger clustering for compact and medium compact clusters than for open clusters, and that open clusters have nearly the same clustering strength as galaxies. A detailed study of the compactness-dependence of correlation function strength is worth investigating. (author)

  20. Modeling conductive heat transfer during high-pressure thawing processes: determination of latent heat as a function of pressure.

    Science.gov (United States)

    Denys, S; Van Loey, A M; Hendrickx, M E

    2000-01-01

    A numerical heat transfer model for predicting product temperature profiles during high-pressure thawing processes was recently proposed by the authors. In the present work, the predictive capacity of the model was considerably improved by taking into account the pressure dependence of the latent heat of the product that was used (Tylose). The effect of pressure on the latent heat of Tylose was experimentally determined by a series of freezing experiments conducted at different pressure levels. By combining a numerical heat transfer model for freezing processes with a least sum of squares optimization procedure, the corresponding latent heat at each pressure level was estimated, and the obtained pressure relation was incorporated in the original high-pressure thawing model. Excellent agreement with the experimental temperature profiles for both high-pressure freezing and thawing was observed.

  1. Cluster analysis for DNA methylation profiles having a detection threshold

    Directory of Open Access Journals (Sweden)

    Siegmund Kimberly D

    2006-07-01

    Full Text Available Abstract Background DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combination of the underlying biology of DNA methylation and the MethyLight technology, the measurements, while being generated on a continuous scale, have a large number of 0 values. This suggests that conventional clustering methodology may not perform well on this data. Results We compare performance of existing methodology (such as k-means with two novel methods that explicitly allow for the preponderance of values at 0. We also consider how the ability to successfully cluster such data depends upon the number of informative genes for which methylation is measured and the correlation structure of the methylation values for those genes. We show that when data is collected for a sufficient number of genes, our models do improve clustering performance compared to methods, such as k-means, that do not explicitly respect the supposed biological realities of the situation. Conclusion The performance of analysis methods depends upon how well the assumptions of those methods reflect the properties of the data being analyzed. Differing technologies will lead to data with differing properties, and should therefore be analyzed differently. Consequently, it is prudent to give thought to what the properties of the data are likely to be, and which analysis method might therefore be likely to best capture those properties.

  2. Cluster-cluster clustering

    International Nuclear Information System (INIS)

    Barnes, J.; Dekel, A.; Efstathiou, G.; Frenk, C.S.; Yale Univ., New Haven, CT; California Univ., Santa Barbara; Cambridge Univ., England; Sussex Univ., Brighton, England)

    1985-01-01

    The cluster correlation function xi sub c(r) is compared with the particle correlation function, xi(r) in cosmological N-body simulations with a wide range of initial conditions. The experiments include scale-free initial conditions, pancake models with a coherence length in the initial density field, and hybrid models. Three N-body techniques and two cluster-finding algorithms are used. In scale-free models with white noise initial conditions, xi sub c and xi are essentially identical. In scale-free models with more power on large scales, it is found that the amplitude of xi sub c increases with cluster richness; in this case the clusters give a biased estimate of the particle correlations. In the pancake and hybrid models (with n = 0 or 1), xi sub c is steeper than xi, but the cluster correlation length exceeds that of the points by less than a factor of 2, independent of cluster richness. Thus the high amplitude of xi sub c found in studies of rich clusters of galaxies is inconsistent with white noise and pancake models and may indicate a primordial fluctuation spectrum with substantial power on large scales. 30 references

  3. Motivational and emotional profiles in university undergraduates: a self-determination theory perspective.

    Science.gov (United States)

    González, Antonio; Paoloni, Verónica; Donolo, Danilo; Rinaudo, Cristina

    2012-11-01

    Previous research has focused on specific forms of self-determined motivation or discrete class-related emotions, but few studies have simultaneously examined both constructs. The aim of this study on 472 undergraduates was twofold: to perform cluster analysis to identify homogeneous groups of motivation in the sample; and to determine the profile of each cluster for emotions and academic achievement. Cluster analysis configured four groups in terms of motivation: controlled, autonomous, both high, and both low. Each cluster revealed a distinct emotional profile, autonomous motivation being the most adaptable with high scores for academic achievement and pleasant emotions and low values for unpleasant emotions. The results are discussed in the light of their implications for academic adjustment.

  4. The Milking Profile of Dairy Cattle Farms in Central Macedonia (Greece

    Directory of Open Access Journals (Sweden)

    Ioannis Mitsopoulos

    2013-05-01

    Full Text Available The purpose of this paper is to provide insights of the profile of the dairy farms of Central Macedonia (Greece, in terms of their milking practices. The analysis is based on data from a random sample of 123 dairy farms, obtained by means of a survey. The employment of the Categorical Principal Component Analysis on the 14 variables initially used to describe milking practices and of the Two-Step Cluster Analysis led to the grouping of the 123 farms to three clusters. Farms of the first cluster, named “Innovative”, use state-of-the-art equipment, automatic systems and innovative milking techniques (31.1% of the sample farms. “Peasant” farms (11.4% are mainly extensive, using mainly bucket plants. The third and most abundant group, the “Modernizing” farms (54.5% are use equipment of reasonable standards and some of them are on the process of renewing it. The results of a Multinomial Logit model verify that “Innovative” farms are large and achieve high yields, while the “Modernizing” ones are smaller, producing milk of lower quality and they are owned by relatively older dairy farmers. An interesting profile is depicted for “Peasant” farms, as they achieve satisfactory economic performance, combined with adequate milk quality. The analytical framework included the reduction of analysis variables to a smaller group of “dimensions”, using the Categorical Principal Component Analysis (CatPCA, based on which farms were clustered to alternative profiles, by employing a Two-Step Cluster (TSC Analysis. Differences in elements of milk quality and in the social profile of farms and farmers were examined among alternative profiles through the estimation of Multinomial Logit Models.

  5. Chemotaxonomy of heterocystous cyanobacteria using FAME profiling as species markers.

    Science.gov (United States)

    Shukla, Ekta; Singh, Satya Shila; Singh, Prashant; Mishra, Arun Kumar

    2012-07-01

    The fatty acid methyl ester (FAME) analysis of the 12 heterocystous cyanobacterial strains showed different fatty acid profiling based on the presence/absence and the percentage of 13 different types of fatty acids. The major fatty acids viz. palmitic acid (16:0), hexadecadienoic acid (16:2), stearic acid (18:0), oleic acid (18:1), linoleic (18:2), and linolenic acid (18:3) were present among all the strains except Cylindrospermum musicola where oleic acid (18:1) was absent. All the strains showed high levels of polyunsaturated fatty acid (PUFAs; 41-68.35%) followed by saturated fatty acid (SAFAs; 1.82-40.66%) and monounsaturated fatty acid (0.85-24.98%). Highest percentage of PUFAs and essential fatty acid (linolenic acid; 18:3) was reported in Scytonema bohnerii which can be used as fatty acid supplement in medical and biotechnological purpose. The cluster analysis based on FAME profiling suggests the presence of two distinct clusters with Euclidean distance ranging from 0 to 25. S. bohnerii of cluster I was distantly related to the other strains of cluster II. The genotypes of cluster II were further divided into two subclusters, i.e., IIa with C. musicola showing great divergence with the other genotypes of IIb which was further subdivided into two groups. Subsubcluster IIb(1) was represented by a genotype, Anabaena sp. whereas subsubcluster IIb(2) was distinguished by two groups, i.e., one group having significant similarity among their three genotypes showed distant relation with the other group having closely related six genotypes. To test the validity of the fatty acid profiles as a marker, cluster analysis has also been generated on the basis of morphological attributes. Our results suggest that FAME profiling might be used as species markers in the study of polyphasic approach based taxonomy and phylogenetic relationship.

  6. CROSS-CORRELATION WEAK LENSING OF SDSS GALAXY CLUSTERS. III. MASS-TO-LIGHT RATIOS

    International Nuclear Information System (INIS)

    Sheldon, Erin S.; Johnston, David E.; Masjedi, Morad; Blanton, Michael R.; McKay, Timothy A.; Scranton, Ryan; Wechsler, Risa H.; Koester, Benjamin P.; Hansen, Sarah M.; Frieman, Joshua A.; Annis, James

    2009-01-01

    We present measurements of the excess mass-to-light ratio (M/L) measured around MaxBCG galaxy clusters observed in the Sloan Digital Sky Survey. This red-sequence cluster sample includes objects from small groups with M 200 ∼ 5 x 10 12 h -1 M sun to clusters with M 200 ∼ 10 15 h -1 M sun . Using cross-correlation weak lensing, we measure the excess mass density profile above the universal mean Δρ(r)=ρ(r)-ρ-bar for clusters in bins of richness and optical luminosity. We also measure the excess luminosity density Δl(r)=l(r)-l-bar measured in the z = 0.25 i band. For both mass and light, we de-project the profiles to produce three-dimensional mass and light profiles over scales from 25 h -1 kpc to 22 h -1 Mpc. From these profiles we calculate the cumulative excess mass ΔM(r) and excess light ΔL(r) as a function of separation from the BCG. On small scales, where ρ(r)>>ρ-bar, the integrated mass-to-light profile (ΔM/ΔL)(r) may be interpreted as the cluster M/L. We find the (ΔM/ΔL) 200 , the M/L within r 200 , scales with cluster mass as a power law with index 0.33 ± 0.02. On large scales, where ρ(r)∼ρ-bar, the ΔM/ΔL approaches an asymptotic value independent of cluster richness. For small groups, the mean (ΔM/ΔL) 200 is much smaller than the asymptotic value, while for large clusters (ΔM/ΔL) 200 is consistent with the asymptotic value. This asymptotic value should be proportional to the mean M/L of the universe (M/L). We find (M/L)b -2 M/L = 362 ± 54h (statistical). There is additional uncertainty in the overall calibration at the ∼10% level. The parameter b 2 M/L is primarily a function of the bias of the L ∼ * galaxies used as light tracers, and should be of order unity. Multiplying by the luminosity density in the same bandpass we find Ω m b -2 M/L = 0.20 ± 0.03, independent of the Hubble parameter.

  7. Association of Ambulatory Blood Pressure Monitoring parameters with the Framingham Stroke Risk Profile.

    Science.gov (United States)

    Tsivgoulis, Georgios; Pikilidou, Maria; Katsanos, Aristeidis H; Stamatelopoulos, Kimon; Michas, Fotios; Lykka, Aikaterini; Zompola, Christina; Filippatou, Angeliki; Boviatsis, Efstathios; Voumvourakis, Konstantinos; Zakopoulos, Nikolaos; Manios, Efstathios

    2017-09-15

    The Framingham Stroke Risk Profile (FSRP) is a novel and reliable tool for estimating the 10-year probability for incident stroke in stroke-free individuals, while the predictive value of ambulatory blood pressure monitoring (ABPM) for first-ever and recurrent stroke has been well established. We sought to evaluate cross-sectionally the association of ABPM parameters with FSRP score in a large sample of 2343 consecutive stroke-free individuals (mean age: 56.0±12.9, 49.1% male) who underwent 24-hour ABPM. True hypertensives showed significantly higher FSRP (11.2±5.0) compared to the normotensives (8.2±5.0, pbest fitting model for predicting FSRP (R 2 =24.6%) on multiple linear regression analyses after adjustment for vascular risk factors not included in FSRP comprised the following parameters in descending order: 24-hour PP (β=0.349, p<0.001), daytime SBP variability (β=0.124, p<0.001), 24-hour HR variability (β=-0.091, p<0.001), mean 24-hour HR (β=-0.107, p<0.001), BMI (β=0.081, p<0.001) and dipping percentage (β=-0.063, p=0.001). 24-hour PP and daytime SBP variability are the two ABPM parameters that were more strongly associated with FSRP-score. Reverse dippers had the highest FSRP among all dipping status profiles. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. ACTIVE GALACTIC NUCLEUS FEEDBACK AND ENTROPY INJECTION IN GALAXY CLUSTER CORES

    International Nuclear Information System (INIS)

    Chaudhuri, Anya; Majumdar, Subhabrata; Nath, Biman B.

    2013-01-01

    We make the first estimate of non-gravitational energy profiles in galaxy cluster cores (and beyond) based on observational data. Comparing the observed entropy profiles within r 500 , from the Representative XMM-Newton Cluster Structure Survey to simulated base entropy profiles without feedback from both adaptive mesh refinement (AMR) and smoothed particle hydrodynamic (SPH) non-radiative simulations, we estimate the amount of additional non-gravitational energy, E ICM , contained in the intracluster medium (ICM), as well as the total energy feedback, E Feedback , from active galactic nuclei (AGNs; the central AGNs in most cases) into the clusters. The total feedback energy scales with the mean spectroscopic temperature as E Feedback ∝T sp 2.52±0.08 and E Feedback ∝T sp 2.17±0.11 for the SPH and AMR baseline profiles. The mean non-gravitational energy per particle within r 500 remaining in the ICM after energy lost during cooling is ε ICM = 2.8 ± 0.8 keV for the SPH theoretical relation and ε ICM = 1.7 ± 0.9 keV for the AMR theoretical relation. We use the NRAO/VLA Sky Survey source catalog to determine the radio luminosity, L R , at 1.4 GHz of the central source(s) of our sample. For T sp > 3 keV, the E Feedback correlates with L R , although with different normalization for cool-core and non-cool-core clusters. We show that AGNs could provide a significant portion of the feedback

  9. The Fornax Cluster VLT Spectroscopic Survey II - Planetary Nebulae kinematics within 200 kpc of the cluster core

    Science.gov (United States)

    Spiniello, C.; Napolitano, N. R.; Arnaboldi, M.; Tortora, C.; Coccato, L.; Capaccioli, M.; Gerhard, O.; Iodice, E.; Spavone, M.; Cantiello, M.; Peletier, R.; Paolillo, M.; Schipani, P.

    2018-06-01

    We present the largest and most spatially extended planetary nebulae (PNe) catalogue ever obtained for the Fornax cluster. We measured velocities of 1452 PNe out to 200 kpc in the cluster core using a counter-dispersed slitless spectroscopic technique with data from FORS2 on the Very Large Telescope (VLT). With such an extended spatial coverage, we can study separately the stellar haloes of some of the cluster main galaxies and the intracluster light. In this second paper of the Fornax Cluster VLT Spectroscopic Survey, we identify and classify the emission-line sources, describe the method to select PNe, and calculate their coordinates and velocities from the dispersed slitless images. From the PN 2D velocity map, we identify stellar streams that are possibly tracing the gravitational interaction of NGC 1399 with NGC 1404 and NGC 1387. We also present the velocity dispersion profile out to ˜200 kpc radii, which shows signatures of a superposition of the bright central galaxy and the cluster potential, with the latter clearly dominating the regions outside R ˜ 1000 arcsec (˜100 kpc).

  10. METHOD OF CONSTRUCTION OF GENETIC DATA CLUSTERS

    Directory of Open Access Journals (Sweden)

    N. A. Novoselova

    2016-01-01

    Full Text Available The paper presents a method of construction of genetic data clusters (functional modules using the randomized matrices. To build the functional modules the selection and analysis of the eigenvalues of the gene profiles correlation matrix is performed. The principal components, corresponding to the eigenvalues, which are significantly different from those obtained for the randomly generated correlation matrix, are used for the analysis. Each selected principal component forms gene cluster. In a comparative experiment with the analogs the proposed method shows the advantage in allocating statistically significant different-sized clusters, the ability to filter non- informative genes and to extract the biologically interpretable functional modules matching the real data structure.

  11. Clusters of Multidrug-Resistant Mycobacterium tuberculosis Cases, Europe

    Science.gov (United States)

    Kremer, Kristin; Heersma, Herre; Van Soolingen, Dick

    2009-01-01

    Molecular surveillance of multidrug-resistant tuberculosis (MDR TB) was implemented in Europe as case reporting in 2005. For all new MDR TB cases detected from January 2003 through June 2007, countries reported case-based epidemiologic data and DNA fingerprint patterns of MDR TB strains when available. International clusters were detected and analyzed. From 2003 through mid-2007 in Europe, 2,494 cases of MDR TB were reported from 24 European countries. Epidemiologic and molecular data were linked for 593 (39%) cases, and 672 insertion sequence 6110 DNA fingerprint patterns were reported from 19 countries. Of these patterns, 288 (43%) belonged to 18 European clusters; 7 clusters (242/288 cases, 84%) were characterized by strains of the Beijing genotype family, including the largest cluster (175/288 cases, 61%). Both clustering and the Beijing genotype were associated with strains originating in eastern European countries. Molecular cluster detection contributes to identification of transmission profile, risk factors, and control measures. PMID:19624920

  12. [Optimization of cluster analysis based on drug resistance profiles of MRSA isolates].

    Science.gov (United States)

    Tani, Hiroya; Kishi, Takahiko; Gotoh, Minehiro; Yamagishi, Yuka; Mikamo, Hiroshige

    2015-12-01

    We examined 402 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from clinical specimens in our hospital between November 19, 2010 and December 27, 2011 to evaluate the similarity between cluster analysis of drug susceptibility tests and pulsed-field gel electrophoresis (PFGE). The results showed that the 402 strains tested were classified into 27 PFGE patterns (151 subtypes of patterns). Cluster analyses of drug susceptibility tests with the cut-off distance yielding a similar classification capability showed favorable results--when the MIC method was used, and minimum inhibitory concentration (MIC) values were used directly in the method, the level of agreement with PFGE was 74.2% when 15 drugs were tested. The Unweighted Pair Group Method with Arithmetic mean (UPGMA) method was effective when the cut-off distance was 16. Using the SIR method in which susceptible (S), intermediate (I), and resistant (R) were coded as 0, 2, and 3, respectively, according to the Clinical and Laboratory Standards Institute (CLSI) criteria, the level of agreement with PFGE was 75.9% when the number of drugs tested was 17, the method used for clustering was the UPGMA, and the cut-off distance was 3.6. In addition, to assess the reproducibility of the results, 10 strains were randomly sampled from the overall test and subjected to cluster analysis. This was repeated 100 times under the same conditions. The results indicated good reproducibility of the results, with the level of agreement with PFGE showing a mean of 82.0%, standard deviation of 12.1%, and mode of 90.0% for the MIC method and a mean of 80.0%, standard deviation of 13.4%, and mode of 90.0% for the SIR method. In summary, cluster analysis for drug susceptibility tests is useful for the epidemiological analysis of MRSA.

  13. Behavioral Health Risk Profiles of Undergraduate University Students in England, Wales, and Northern Ireland: A Cluster Analysis.

    Science.gov (United States)

    El Ansari, Walid; Ssewanyana, Derrick; Stock, Christiane

    2018-01-01

    Limited research has explored clustering of lifestyle behavioral risk factors (BRFs) among university students. This study aimed to explore clustering of BRFs, composition of clusters, and the association of the clusters with self-rated health and perceived academic performance. We assessed (BRFs), namely tobacco smoking, physical inactivity, alcohol consumption, illicit drug use, unhealthy nutrition, and inadequate sleep, using a self-administered general Student Health Survey among 3,706 undergraduates at seven UK universities. A two-step cluster analysis generated: Cluster 1 (the high physically active and health conscious) with very high health awareness/consciousness, good nutrition, and physical activity (PA), and relatively low alcohol, tobacco, and other drug (ATOD) use. Cluster 2 (the abstinent) had very low ATOD use, high health awareness, good nutrition, and medium high PA. Cluster 3 (the moderately health conscious) included the highest regard for healthy eating, second highest fruit/vegetable consumption, and moderately high ATOD use. Cluster 4 (the risk taking) showed the highest ATOD use, were the least health conscious, least fruit consuming, and attached the least importance on eating healthy. Compared to the healthy cluster (Cluster 1), students in other clusters had lower self-rated health, and particularly, students in the risk taking cluster (Cluster 4) reported lower academic performance. These associations were stronger for men than for women. Of the four clusters, Cluster 4 had the youngest students. Our results suggested that prevention among university students should address multiple BRFs simultaneously, with particular focus on the younger students.

  14. STAR CLUSTER FORMATION WITH STELLAR FEEDBACK AND LARGE-SCALE INFLOW

    International Nuclear Information System (INIS)

    Matzner, Christopher D.; Jumper, Peter H.

    2015-01-01

    During star cluster formation, ongoing mass accretion is resisted by stellar feedback in the form of protostellar outflows from the low-mass stars and photo-ionization and radiation pressure feedback from the massive stars. We model the evolution of cluster-forming regions during a phase in which both accretion and feedback are present and use these models to investigate how star cluster formation might terminate. Protostellar outflows are the strongest form of feedback in low-mass regions, but these cannot stop cluster formation if matter continues to flow in. In more massive clusters, radiation pressure and photo-ionization rapidly clear the cluster-forming gas when its column density is too small. We assess the rates of dynamical mass ejection and of evaporation, while accounting for the important effect of dust opacity on photo-ionization. Our models are consistent with the census of protostellar outflows in NGC 1333 and Serpens South and with the dust temperatures observed in regions of massive star formation. Comparing observations of massive cluster-forming regions against our model parameter space, and against our expectations for accretion-driven evolution, we infer that massive-star feedback is a likely cause of gas disruption in regions with velocity dispersions less than a few kilometers per second, but that more massive and more turbulent regions are too strongly bound for stellar feedback to be disruptive

  15. Distinct profile of vascular progenitor attachment to extracellular matrix proteins in cancer patients.

    Science.gov (United States)

    Labonté, Laura; Li, Yuhua; Addison, Christina L; Brand, Marjorie; Javidnia, Hedyeh; Corsten, Martin; Burns, Kevin; Allan, David S

    2012-04-01

    Vascular progenitor cells (VPCs) facilitate angiogenesis and initiate vascular repair by homing in on sites of damage and adhering to extracellular matrix (ECM) proteins. VPCs also contribute to tumor angiogenesis and induce angiogenic switching in sites of metastatic cancer. In this study, the binding of attaching cells in VPC clusters that form in vitro on specific ECM proteins was investigated. VPC cluster assays were performed in vitro on ECM proteins enriched in cancer cells and in remodelling tissue. Profiles of VPC clusters from patients with cancer were compared to healthy controls. The role of VEGF and integrin-specific binding of angiogenic attaching cells was addressed. VPC clusters from cancer patients were markedly increased on fibronectin relative to other ECM proteins tested, in contrast to VPC clusters from control subjects, which formed preferentially on laminin. Specific integrin-mediated binding of attaching cells in VPC clusters was matrix protein-dependent. Furthermore, cancer patients had elevated plasma VEGF levels compared to healthy controls and VEGF facilitated preferential VPC cluster formation on fibronectin. Incubating cells from healthy controls with VEGF induced a switch from the 'healthy' VPC binding profile to the profile observed in cancer patients with a marked increase in VPC cluster formation on fibronectin. The ECM proteins laminin and fibronectin support VPC cluster formation via specific integrins on attaching cells and can facilitate patterns of VPC cluster formation that are distinct in cancer patients. Larger studies, however, are needed to gain insight on how tumor angiogenesis may differ from normal repair processes.

  16. Temperature profile and pressure data from CTD casts in the Northwest Atlantic Ocean from 19 April 2001 to 15 December 2001 (NODC Accession 0000370)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile and pressure data were collected from the NAVIGATION RESPONSE TEAM 2 from April 19, 2001 to December 15, 2001. Data were submitted by National...

  17. Pregalactic formation of globular clusters in cold dark matter

    International Nuclear Information System (INIS)

    Faber, S.M.; Blumenthal, G.R.; Rosenblatt, E.I.

    1988-01-01

    The pregalactic hypothesis for the formation of globular clusters is reconsidered in the light of Zinn's (1985) discovery of a two-component globular population in the Milky Way. For a cold dark matter spectrum, high-sigma fluctuations of 10 to the 5th - 10 to the 6th solar masses are assumed to be the progenitors of the spheroidal population of globular clusters. The mass fraction of globular clusters in galaxies then requires that perturbations above roughly 2.8 sigma survive as globulars, and their observed radii require baryonic collapse factors of order 10. Such an absolute density threshold for globular cluster formation achieves adequate fits to observed cluster radii and densities, the mass fraction of globulars versus Hubble type, the radial density profile of globulars within galaxies, and the globular luminosity function. However, a fixed density threshold criterion for cluster survival lacks convincing physical justification and does not by itself explain the homogeneous metallicities within clusters or the large metallicity variations from cluster to cluster and from galaxy to galaxy. 33 references

  18. Cluster infall in the concordance LCDM model

    OpenAIRE

    Pivato, Maximiliano C.; Padilla, Nelson D.; Lambas, Diego G.

    2005-01-01

    We perform statistical analyses of the infall of dark-matter onto clusters in numerical simulations within the concordance LCDM model. By studying the infall profile around clusters of different mass, we find a linear relation between the maximum infall velocity and mass which reach 900km/s for the most massive groups. The maximum infall velocity and the group mass follow a suitable power law fit of the form, V_{inf}^{max} = (M/m_0)^{gamma}. By comparing the measured infall velocity to the li...

  19. WISC-IV Profiles Are Associated with Differences in Symptomatology and Outcome in Children with ADHD

    Science.gov (United States)

    Thaler, Nicholas S.; Bello, Danielle T.; Etcoff, Lewis M.

    2013-01-01

    Objective: The current study investigated the Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV) cluster profiles of children with ADHD to examine the association between IQ profiles and diagnostic frequency, symptomatology, and outcome in this population. Method: Hierarchical cluster analysis was conducted on 189 children with a…

  20. Constructing Ozone Profile Climatologies with Self-Organizing Maps: Illustrations with CONUS Ozonesonde Data

    Science.gov (United States)

    Thompson, A. M.; Stauffer, R. M.; Young, G. S.

    2015-12-01

    Ozone (O3) trends analysis is typically performed with monthly or seasonal averages. Although this approach works well for stratospheric or total O3, uncertainties in tropospheric O3 amounts may be large due to rapid meteorological changes near the tropopause and in the lower free troposphere (LFT) where pollution has a days-weeks lifetime. We use self-organizing maps (SOM), a clustering technique, as an alternative for creating tropospheric climatologies from O3 soundings. In a previous study of 900 tropical ozonesondes, clusters representing >40% of profiles deviated > 1-sigma from mean O­3. Here SOM are based on 15 years of data from four sites in the contiguous US (CONUS; Boulder, CO; Huntsville, AL; Trinidad Head, CA; Wallops Island, VA). Ozone profiles from 2 - 12 km are used to evaluate the impact of tropopause variability on climatology; 2 - 6 km O3 profile segments are used for the LFT. Near-tropopause O­3 is twice the mean O­3 mixing ratio in three clusters of 2 - 12 km O3, representing > 15% of profiles at each site. Large mid and lower-tropospheric O3 deviations from monthly means are found in clusters of both 2 - 12 and 2 - 6 km O3. Positive offsets result from pollution and stratosphere-to-troposphere exchange. In the LFT the lowest tropospheric O3 is associated with subtropical air. Some clusters include profiles with common seasonality but other factors, e.g., tropopause height or LFT column amount, characterize other SOM nodes. Thus, as for tropical profiles, CONUS O­3 averages can be a poor choice for a climatology.

  1. Fischer–Tropsch Synthesis at a Low Pressure on Subnanometer Cobalt Oxide Clusters: The Effect of Cluster Size and Support on Activity and Selectivity

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sungsik; Lee, Byeongdu; Seifert, Sönke; Winans, Randall E.; Vajda, Stefan

    2015-05-21

    In this study, the catalytic activity and changes in the oxidation state during the Fischer Tropsch (FT) reaction was investigated on subnanometer size-selected cobalt clusters deposited on oxide (Al2O3, MgO) and carbon-based (ultrananocrystalline diamond UNCD) supports by temperature programmed reaction (TPRx) combined with in-situ grazing-incidence X-ray absorption characterization (GIXAS). The activity and selectivity of ultrasmall cobalt clusters exhibits a very strong dependence on cluster size and support. The evolution of the oxidation state of metal cluster during the reaction reveals that metal-support interaction plays a key role in the reaction.

  2. Behavioral Health Risk Profiles of Undergraduate University Students in England, Wales, and Northern Ireland: A Cluster Analysis

    Directory of Open Access Journals (Sweden)

    Walid El Ansari

    2018-05-01

    Full Text Available BackgroundLimited research has explored clustering of lifestyle behavioral risk factors (BRFs among university students. This study aimed to explore clustering of BRFs, composition of clusters, and the association of the clusters with self-rated health and perceived academic performance.MethodWe assessed (BRFs, namely tobacco smoking, physical inactivity, alcohol consumption, illicit drug use, unhealthy nutrition, and inadequate sleep, using a self-administered general Student Health Survey among 3,706 undergraduates at seven UK universities.ResultsA two-step cluster analysis generated: Cluster 1 (the high physically active and health conscious with very high health awareness/consciousness, good nutrition, and physical activity (PA, and relatively low alcohol, tobacco, and other drug (ATOD use. Cluster 2 (the abstinent had very low ATOD use, high health awareness, good nutrition, and medium high PA. Cluster 3 (the moderately health conscious included the highest regard for healthy eating, second highest fruit/vegetable consumption, and moderately high ATOD use. Cluster 4 (the risk taking showed the highest ATOD use, were the least health conscious, least fruit consuming, and attached the least importance on eating healthy. Compared to the healthy cluster (Cluster 1, students in other clusters had lower self-rated health, and particularly, students in the risk taking cluster (Cluster 4 reported lower academic performance. These associations were stronger for men than for women. Of the four clusters, Cluster 4 had the youngest students.ConclusionOur results suggested that prevention among university students should address multiple BRFs simultaneously, with particular focus on the younger students.

  3. Consideration of possible mass and velocity corrections to magnetic cluster experiments

    International Nuclear Information System (INIS)

    Liu, Z.Y.; Dowben, P.A.; Popov, A.P.; Pappas, David P.

    2003-01-01

    Gadolinium occurs, in natural abundance, as several isotopes. The possible combinations of different gadolinium isotopes dictates that even for a fixed number of atoms in the cluster, clusters of gadolinium atoms will exhibit a range of masses. This and the expected consequence of the translation energy distributions are explored as possible corrections to Stern-Gerlach cluster beam-deflection experiments. Upon closer inspection of the experimental data, we find that the translation energy plus the vibrational temperature distribution may be inhomogeneous. This could be the origin of a long tail to high deflections in the experimental deflection profiles, at low cluster temperatures, in the magnetic cluster Stern-Gerlach experiments

  4. Assessment of the Quality of the Version 1.07 Temperature-Versus-Pressure Profiles of the Middle Atmosphere from TIMED/SABER

    Science.gov (United States)

    Remsberg, E. E.; Marshall, B. T.; Garcia-Comas, M.; Krueger, D.; Lingenfelser, G. S.; Martin-Torres, J.; Mlynczak, M. G.; Russell, J. M., III; Smith, A. K.; Zhao, Y.; hide

    2008-01-01

    The quality of the retrieved temperature-versus-pressure (or T(p)) profiles is described for the middle atmosphere for the publicly available Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) Version 1.07 (V1.07) data set. The primary sources of systematic error for the SABER results below about 70 km are (1) errors in the measured radiances, (2) biases in the forward model, and (3) uncertainties in the corrections for ozone and in the determination of the reference pressure for the retrieved profiles. Comparisons with other correlative data sets indicate that SABER T(p) is too high by 1-3 K in the lower stratosphere but then too low by 1 K near the stratopause and by 2 K in the middle mesosphere. There is little difference between the local thermodynamic equilibrium (LTE) algorithm results below about 70 km from V1.07 and V1.06, but there are substantial improvements/differences for the non-LTE results of V1.07 for the upper mesosphere and lower thermosphere (UMLT) region. In particular, the V1.07 algorithm uses monthly, diurnally averaged CO2 profiles versus latitude from the Whole Atmosphere Community Climate Model. This change has improved the consistency of the character of the tides in its kinetic temperature (T(sub k)). The T(sub k) profiles agree with UMLT values obtained from ground-based measurements of column-averaged OH and O2 emissions and of the Na lidar returns, at least within their mutual uncertainties. SABER T(sub k) values obtained near the mesopause with its daytime algorithm also agree well with the falling sphere climatology at high northern latitudes in summer. It is concluded that the SABER data set can be the basis for improved, diurnal-to-interannual-scale temperatures for the middle atmosphere and especially for its UMLT region.

  5. Implicit User Interest Profile

    CERN Document Server

    Chan, K

    2002-01-01

    User interest profile presents items that the users are interested in. Typically those items can be listed or grouped. Listing is good but it does not possess interests at different abstraction levels - the higher-level interests are more general, while the lower-level ones are more specific. Furthermore, more general interests, in some sense, correspond to longer-term interests, while more specific interests correspond to shorter-term interests. This hierarchical user interest profile has obvious advantages: specifying user's specific interests and general interests and representing their relationships. Current user interest profile structures mostly do not use implicit method, nor use an appropriate clustering algorithm especially for conceptually hierarchical structures. This research studies building a hierarchical user interest profile (HUIP) and the hierarchical divisive algorithm (HDC). Several users visit hundreds of web pages and each page is recorded in each users profile. These web pages are used t...

  6. Deconstructing Bipolar Disorder and Schizophrenia: A cross-diagnostic cluster analysis of cognitive phenotypes.

    Science.gov (United States)

    Lee, Junghee; Rizzo, Shemra; Altshuler, Lori; Glahn, David C; Miklowitz, David J; Sugar, Catherine A; Wynn, Jonathan K; Green, Michael F

    2017-02-01

    Bipolar disorder (BD) and schizophrenia (SZ) show substantial overlap. It has been suggested that a subgroup of patients might contribute to these overlapping features. This study employed a cross-diagnostic cluster analysis to identify subgroups of individuals with shared cognitive phenotypes. 143 participants (68 BD patients, 39 SZ patients and 36 healthy controls) completed a battery of EEG and performance assessments on perception, nonsocial cognition and social cognition. A K-means cluster analysis was conducted with all participants across diagnostic groups. Clinical symptoms, functional capacity, and functional outcome were assessed in patients. A two-cluster solution across 3 groups was the most stable. One cluster including 44 BD patients, 31 controls and 5 SZ patients showed better cognition (High cluster) than the other cluster with 24 BD patients, 35 SZ patients and 5 controls (Low cluster). BD patients in the High cluster performed better than BD patients in the Low cluster across cognitive domains. Within each cluster, participants with different clinical diagnoses showed different profiles across cognitive domains. All patients are in the chronic phase and out of mood episode at the time of assessment and most of the assessment were behavioral measures. This study identified two clusters with shared cognitive phenotype profiles that were not proxies for clinical diagnoses. The finding of better social cognitive performance of BD patients than SZ patients in the Lowe cluster suggest that relatively preserved social cognition may be important to identify disease process distinct to each disorder. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. YOUNG ATHLETES' MOTIVATIONAL PROFILES

    Directory of Open Access Journals (Sweden)

    Juan Antonio Moreno Murcia

    2007-06-01

    Full Text Available The aim of this study was to examine the relationship between motivational characteristics and dispositional flow. In order to accomplish this goal, motivational profiles emerging from key constructs within Achievement Goal Theory and Self-Determination Theory were related to the dispositional flow measures. A sample of 413 young athletes (Age range 12 to 16 years completed the PMCSQ-2, POSQ, SMS and DFS measures. Cluster analysis results revealed three profiles: a "self-determined profile" characterised by higher scores on the task-involving climate perception and on the task orientation; a "non-self-determined profile", characterised by higher scores on ego-involving climate perception and ego orientation; and a "low self-determined and low non-self-determined profile" which had the lowest dispositional flow. No meaningful differences were found between the "self-determined profile" and the "non-self-determined profile" in dispositional flow. The "self-determined profile" was more commonly associated with females, athletes practising individual sports and those training more than three days a week. The "non-self-determined profile" was more customary of males and athletes practising team sports as well as those training just two or three days a week

  8. Subtypes of borderline personality disorder patients: a cluster-analytic approach.

    Science.gov (United States)

    Smits, Maaike L; Feenstra, Dine J; Bales, Dawn L; de Vos, Jasmijn; Lucas, Zwaan; Verheul, Roel; Luyten, Patrick

    2017-01-01

    The borderline personality disorder (BPD) population is notably heterogeneous, and this has potentially important implications for intervention. Identifying distinct subtypes of patients may represent a first step in identifying which treatments work best for which individuals. A cluster-analysis on dimensional personality disorder (PD) features, as assessed with the SCID-II, was performed on a sample of carefully screened BPD patients ( N  = 187) referred for mentalization-based treatment. The optimal cluster solution was determined using multiple indices of fit. The validity of the clusters was explored by investigating their relationship with borderline pathology, symptom severity, interpersonal problems, quality of life, personality functioning, attachment, and trauma history, in addition to demographic and clinical features. A three-cluster solution was retained, which identified three clusters of BPD patients with distinct profiles. The largest cluster ( n  = 145) consisted of patients characterized by "core BPD" features, without marked elevations on other PD dimensions. A second "Extravert/externalizing" cluster of patients ( n  = 27) was characterized by high levels of histrionic, narcissistic, and antisocial features. A third, smaller "Schizotypal/paranoid" cluster ( n  = 15) consisted of patients with marked schizotypal and paranoid features. Patients in these clusters showed theoretically meaningful differences in terms of demographic and clinical features. Three meaningful subtypes of BPD patients were identified with distinct profiles. Differences were small, even when controlling for severity of PD pathology, suggesting a strong common factor underlying BPD. These results may represent a stepping stone toward research with larger samples aimed at replicating the findings and investigating differential trajectories of change, treatment outcomes, and treatment approaches for these subtypes. The study was retrospectively registered 16 April 2010

  9. Effects of supervised exercise on lipid profiles and blood pressure control in people with type 2 diabetes mellitus: a meta-analysis of randomized controlled trials.

    Science.gov (United States)

    Hayashino, Yasuaki; Jackson, Jeffrey L; Fukumori, Norio; Nakamura, Fumiaki; Fukuhara, Shunichi

    2012-12-01

    Our study's purpose was to perform a systematic review to assess the effect of supervised exercise interventions on lipid profiles and blood pressure control. We searched electronic databases and selected studies that evaluated the effect of supervised exercise intervention on cardiovascular risk factors in adult people with type 2 diabetes. We used random effect models to derive weighted mean differences of exercise on lipid profiles and blood pressure control. Forty-two RCTs (2808 subjects) met inclusion criteria and are included in our meta-analysis. Structured exercise was associated with a change in systolic blood pressure (SBP) of -2.42 mmHg (95% CI, -4.39 to -0.45 mmHg), diastolic blood pressure (DBP) of -2.23 mmHg (95% CI, -3.21 to -1.25 mmHg), high-density lipoprotein cholesterol (HDL-C) of 0.04 mmol/L (95% CI, 0.02-0.07 mmol/L), and low-density lipoprotein cholesterol (LDL-C) of -0.16 mmol/L (95% CI, -0.30 to -0.01 mmol/L). Heterogeneity was partially explained by age, dietary co-intervention and the duration and intensity of the exercise. Supervised exercise is effective in improving blood pressure control, lowering LDL-C, and elevating HDL-C levels in people with diabetes. Physicians should recommend exercise for their adult patients with diabetes who can safely do so. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  10. Concomitant formation of different nature clusters and hardening in reactor pressure vessel steels irradiated by heavy ions

    Energy Technology Data Exchange (ETDEWEB)

    Fujii, K., E-mail: fujiik@inss.co.jp [Institute of Nuclear Safety System, Inc., Mihama 919-1205 (Japan); Fukuya, K. [Institute of Nuclear Safety System, Inc., Mihama 919-1205 (Japan); Hojo, T. [Japan Nuclear Energy Safety Organization, Toranomon, Minato-ku, Tokyo 105-0001 (Japan)

    2013-11-15

    Specimens of A533B steels containing 0.04, 0.09 and 0.21 wt%Cu were irradiated at 290 °C to 3 dpa with 3 MeV Fe ions and subjected to atom probe analyses, transmission electron microscopy observations and hardness measurements. The atom probe analysis results showed that two types of solute clusters were formed: Cu-enriched clusters containing Mn, Ni and Si atoms as irradiation-enhanced solute atom clusters and Mn/Ni/Si-enriched clusters as irradiation-induced solute atom clusters. Both cluster types occurred in the highest Cu-content steel and the ratio of Mn/Ni/Si-enriched clusters to Cu-enriched clusters increased with irradiation doses. It was confirmed that the cluster formation was a key factor in the microstructure evolution until the high dose irradiation was reached even in the low Cu content steels though the dislocation loops with much lower density than that of the clusters were observed as matrix damage. The difference in the hardening efficiency due to the difference in the nature of the clusters was small. The irradiation-induced clustering of undersized Si atoms suggested that a clustering driving force other than vacancy-driven diffusion, probably an interstitial mechanism, may become important at higher dose rates.

  11. Concomitant formation of different nature clusters and hardening in reactor pressure vessel steels irradiated by heavy ions

    International Nuclear Information System (INIS)

    Fujii, K.; Fukuya, K.; Hojo, T.

    2013-01-01

    Specimens of A533B steels containing 0.04, 0.09 and 0.21 wt%Cu were irradiated at 290 °C to 3 dpa with 3 MeV Fe ions and subjected to atom probe analyses, transmission electron microscopy observations and hardness measurements. The atom probe analysis results showed that two types of solute clusters were formed: Cu-enriched clusters containing Mn, Ni and Si atoms as irradiation-enhanced solute atom clusters and Mn/Ni/Si-enriched clusters as irradiation-induced solute atom clusters. Both cluster types occurred in the highest Cu-content steel and the ratio of Mn/Ni/Si-enriched clusters to Cu-enriched clusters increased with irradiation doses. It was confirmed that the cluster formation was a key factor in the microstructure evolution until the high dose irradiation was reached even in the low Cu content steels though the dislocation loops with much lower density than that of the clusters were observed as matrix damage. The difference in the hardening efficiency due to the difference in the nature of the clusters was small. The irradiation-induced clustering of undersized Si atoms suggested that a clustering driving force other than vacancy-driven diffusion, probably an interstitial mechanism, may become important at higher dose rates

  12. Induction of nitrate tolerance is not a useful treatment in cluster headache

    DEFF Research Database (Denmark)

    Christiansen, I; Iversen, Helle Klingenberg; Olesen, J

    2000-01-01

    UNLABELLED: The aims of the present study were to investigate whether induction of nitrate tolerance is a useful treatment in cluster headache and to correlate any changes in attack frequency of cluster headache and nitrate-induced headache to the vascular adaptation during continuous nitrate...... attacks and interval headaches over time. RESULTS: Tolerance was complete within 24 h in the middle cerebral arteries and after 7 days in the symptomatic temporal artery, while tolerance of the radial artery was not observed within this period. The time profiles of tolerance were almost identical...... to the time profiles observed in healthy subjects. A close temporal association between the disappearance of nitrate-induced headache and tolerance of the temporal artery was observed but tolerance had no effect on cluster headache attack frequency. CONCLUSIONS: Induction of tolerance to nitrates cannot...

  13. Clustering-based approaches to SAGE data mining

    Directory of Open Access Journals (Sweden)

    Wang Haiying

    2008-07-01

    Full Text Available Abstract Serial analysis of gene expression (SAGE is one of the most powerful tools for global gene expression profiling. It has led to several biological discoveries and biomedical applications, such as the prediction of new gene functions and the identification of biomarkers in human cancer research. Clustering techniques have become fundamental approaches in these applications. This paper reviews relevant clustering techniques specifically designed for this type of data. It places an emphasis on current limitations and opportunities in this area for supporting biologically-meaningful data mining and visualisation.

  14. Contributions of Cu-rich clusters, dislocation loops and nanovoids to the irradiation-induced hardening of Cu-bearing low-Ni reactor pressure vessel steels

    Energy Technology Data Exchange (ETDEWEB)

    Bergner, F., E-mail: f.bergner@hzdr.de [Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstr. 400, 01328 Dresden (Germany); Gillemot, F. [Centre for Energy Research of the Hungarian Academy of Sciences, 29-33 Konkoly-Thege street, 1121 Budapest XII (Hungary); Hernández-Mayoral, M.; Serrano, M. [Division of Materials, CIEMAT, Avenida Complutense 22, 28040 Madrid (Spain); Török, G. [Wigner Research Center for Physics of the Hungarian Academy of Sciences, 29-33 Konkoly-Thege street, 1121 Budapest XII (Hungary); Ulbricht, A.; Altstadt, E. [Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstr. 400, 01328 Dresden (Germany)

    2015-06-15

    Highlights: • TEM and SANS were applied to estimate mean size and number density of loops, nanovoids and Cu-rich clusters. • A three-feature dispersed-barrier hardening model was applied to estimate the yield stress increase. • The values and errors of the dimensionless obstacle strength were estimated in a consistent way. • Nanovoids are stronger obstacles for dislocation glide than dislocation loops, loops are stronger than Cu-rich clusters. • For reactor-relevant conditions, Cu-rich clusters contribute most to hardening due to their high number density. - Abstract: Dislocation loops, nanovoids and Cu-rich clusters (CRPs) are known to represent obstacles for dislocation glide in neutron-irradiated reactor pressure vessel (RPV) steels, but a consistent experimental determination of the respective obstacle strengths is still missing. A set of Cu-bearing low-Ni RPV steels and model alloys was characterized by means of SANS and TEM in order to specify mean size and number density of loops, nanovoids and CRPs. The obstacle strengths of these families were estimated by solving an over-determined set of linear equations. We have found that nanovoids are stronger than loops and loops are stronger than CRPs. Nevertheless, CRPs contribute most to irradiation hardening because of their high number density. Nanovoids were only observed for neutron fluences beyond typical end-of-life conditions of RPVs. The estimates of the obstacle strength are critically compared with reported literature data.

  15. Weighing galaxy clusters with gas. II. On the origin of hydrostatic mass bias in ΛCDM galaxy clusters

    International Nuclear Information System (INIS)

    Nelson, Kaylea; Nagai, Daisuke; Yu, Liang; Lau, Erwin T.; Rudd, Douglas H.

    2014-01-01

    The use of galaxy clusters as cosmological probes hinges on our ability to measure their masses accurately and with high precision. Hydrostatic mass is one of the most common methods for estimating the masses of individual galaxy clusters, which suffer from biases due to departures from hydrostatic equilibrium. Using a large, mass-limited sample of massive galaxy clusters from a high-resolution hydrodynamical cosmological simulation, in this work we show that in addition to turbulent and bulk gas velocities, acceleration of gas introduces biases in the hydrostatic mass estimate of galaxy clusters. In unrelaxed clusters, the acceleration bias is comparable to the bias due to non-thermal pressure associated with merger-induced turbulent and bulk gas motions. In relaxed clusters, the mean mass bias due to acceleration is small (≲ 3%), but the scatter in the mass bias can be reduced by accounting for gas acceleration. Additionally, this acceleration bias is greater in the outskirts of higher redshift clusters where mergers are more frequent and clusters are accreting more rapidly. Since gas acceleration cannot be observed directly, it introduces an irreducible bias for hydrostatic mass estimates. This acceleration bias places limits on how well we can recover cluster masses from future X-ray and microwave observations. We discuss implications for cluster mass estimates based on X-ray, Sunyaev-Zel'dovich effect, and gravitational lensing observations and their impact on cluster cosmology.

  16. The Formation and Evolution of Star Clusters in Interacting Galaxies

    Science.gov (United States)

    Maji, Moupiya; Zhu, Qirong; Li, Yuexing; Charlton, Jane; Hernquist, Lars; Knebe, Alexander

    2017-08-01

    Observations of globular clusters show that they have universal lognormal mass functions with a characteristic peak at ˜ 2× {10}5 {M}⊙ , but the origin of this peaked distribution is highly debated. Here we investigate the formation and evolution of star clusters (SCs) in interacting galaxies using high-resolution hydrodynamical simulations performed with two different codes in order to mitigate numerical artifacts. We find that massive SCs in the range of ˜ {10}5.5{--}{10}7.5 {M}⊙ form preferentially in the highly shocked regions produced by galaxy interactions. The nascent cluster-forming clouds have high gas pressures in the range of P/k˜ {10}8{--}{10}12 {{K}} {{cm}}-3, which is ˜ {10}4{--}{10}8 times higher than the typical pressure of the interstellar medium but consistent with recent observations of a pre-super-SC cloud in the Antennae Galaxies. Furthermore, these massive SCs have quasi-lognormal initial mass functions with a peak around ˜ {10}6 {M}⊙ . The number of clusters declines with time due to destructive processes, but the shape and the peak of the mass functions do not change significantly during the course of galaxy collisions. Our results suggest that gas-rich galaxy mergers may provide a favorable environment for the formation of massive SCs such as globular clusters, and that the lognormal mass functions and the unique peak may originate from the extreme high-pressure conditions of the birth clouds and may survive the dynamical evolution.

  17. Percolation approach for atomic and molecular cluster formation

    International Nuclear Information System (INIS)

    Knospe, O.; Seifert, G.

    1987-12-01

    We apply a percolation approach for the theoretical analysis of mass spectra of molecular microclusters obtained by adiabatic expansion technique. The evolution of the shape of the experimental size distributions as function of stagnation pressure and stagnation temperature are theoretically reproduced by varying the percolation parameter. Remaining discrepancies between theory and experiment are discussed. In addition, the even-odd alternation as well as the 'magic' shell structure within metallic, secondary ion mass spectra are investigated by introducing statistical weights for the cluster formation probabilities. Shell correction energies of atomic clusters as function of cluster-size are deduced from the experimental data. (orig.)

  18. The quiescent intracluster medium in the core of the Perseus cluster

    Energy Technology Data Exchange (ETDEWEB)

    Aharonian, Felix; Akamatsu, Hiroki; Akimoto, Fumie; Allen, Steven W.; Anabuki, Naohisa; Angelini, Lorella; Arnaud, Keith; Audard, Marc; Awaki, Hisamitsu; Axelsson, Magnus; Bamba, Aya; Bautz, Marshall; Blandford, Roger; Brenneman, Laura; Brown, Gregory V.; Bulbul, Esra; Cackett, Edward; Chernyakova, Maria; Chiao, Meng; Coppi, Paolo; Costantini, Elisa; de Plaa, Jelle; den Herder, Jan-Willem; Done, Chris; Dotani, Tadayasu; Ebisawa, Ken; Eckart, Megan; Enoto, Teruaki; Ezoe, Yuichiro; Fabian, Andrew C.; Ferrigno, Carlo; Foster, Adam; Fujimoto, Ryuichi; Fukazawa, Yasushi; Furuzawa, Akihiro; Galeazzi, Massimiliano; Gallo, Luigi; Gandhi, Poshak; Giustini, Margherita; Goldwurm, Andrea; Gu, Liyi; Guainazzi, Matteo; Haba, Yoshito; Hagino, Kouichi; Hamaguchi, Kenji; Harrus, Ilana; Hatsukade, Isamu; Hayashi, Katsuhiro; Hayashi, Takayuki; Hayashida, Kiyoshi; Hiraga, Junko; Hornschemeier, Ann; Hoshino, Akio; Hughes, John; Iizuka, Ryo; Inoue, Hajime; Inoue, Yoshiyuki; Ishibashi, Kazunori; Ishida, Manabu; Ishikawa, Kumi; Ishisaki, Yoshitaka; Itoh, Masayuki; Iyomoto, Naoko; Kaastra, Jelle; Kallman, Timothy; Kamae, Tuneyoshi; Kara, Erin; Kataoka, Jun; Katsuda, Satoru; Katsuta, Junichiro; Kawaharada, Madoka; Kawai, Nobuyuki; Kelley, Richard; Khangulyan, Dmitry; Kilbourne, Caroline; King, Ashley; Kitaguchi, Takao; Kitamoto, Shunji; Kitayama, Tetsu; Kohmura, Takayoshi; Kokubun, Motohide; Koyama, Shu; Koyama, Katsuji; Kretschmar, Peter; Krimm, Hans; Kubota, Aya; Kunieda, Hideyo; Laurent, Philippe; Lebrun, François; Lee, Shiu-Hang; Leutenegger, Maurice; Limousin, Olivier; Loewenstein, Michael; Long, Knox S.; Lumb, David; Madejski, Grzegorz; Maeda, Yoshitomo; Maier, Daniel; Makishima, Kazuo; Markevitch, Maxim; Matsumoto, Hironori; Matsushita, Kyoko; McCammon, Dan; McNamara, Brian; Mehdipour, Missagh; Miller, Eric; Miller, Jon; Mineshige, Shin; Mitsuda, Kazuhisa; Mitsuishi, Ikuyuki; Miyazawa, Takuya; Mizuno, Tsunefumi; Mori, Hideyuki; Mori, Koji; Moseley, Harvey; Mukai, Koji; Murakami, Hiroshi; Murakami, Toshio; Mushotzky, Richard; Nagino, Ryo; Nakagawa, Takao; Nakajima, Hiroshi; Nakamori, Takeshi; Nakano, Toshio; Nakashima, Shinya; Nakazawa, Kazuhiro; Nobukawa, Masayoshi; Noda, Hirofumi; Nomachi, Masaharu; O’Dell, Steve; Odaka, Hirokazu; Ohashi, Takaya; Ohno, Masanori; Okajima, Takashi; Ota, Naomi; Ozaki, Masanobu; Paerels, Frits; Paltani, Stephane; Parmar, Arvind; Petre, Robert; Pinto, Ciro; Pohl, Martin; Porter, F. Scott; Pottschmidt, Katja; Ramsey, Brian; Reynolds, Christopher; Russell, Helen; Safi-Harb, Samar; Saito, Shinya; Sakai, Kazuhiro; Sameshima, Hiroaki; Sato, Goro; Sato, Kosuke; Sato, Rie; Sawada, Makoto; Schartel, Norbert; Serlemitsos, Peter; Seta, Hiromi; Shidatsu, Megumi; Simionescu, Aurora; Smith, Randall; Soong, Yang; Stawarz, Lukasz; Sugawara, Yasuharu; Sugita, Satoshi; Szymkowiak, Andrew; Tajima, Hiroyasu; Takahashi, Hiromitsu; Takahashi, Tadayuki; Takeda, Shin’ichiro; Takei, Yoh; Tamagawa, Toru; Tamura, Keisuke; Tamura, Takayuki; Tanaka, Takaaki; Tanaka, Yasuo; Tanaka, Yasuyuki; Tashiro, Makoto; Tawara, Yuzuru; Terada, Yukikatsu; Terashima, Yuichi; Tombesi, Francesco; Tomida, Hiroshi; Tsuboi, Yohko; Tsujimoto, Masahiro; Tsunemi, Hiroshi; Tsuru, Takeshi; Uchida, Hiroyuki; Uchiyama, Hideki; Uchiyama, Yasunobu; Ueda, Shutaro; Ueda, Yoshihiro; Ueno, Shiro; Uno, Shin’ichiro; Urry, Meg; Ursino, Eugenio; de Vries, Cor; Watanabe, Shin; Werner, Norbert; Wik, Daniel; Wilkins, Dan; Williams, Brian; Yamada, Shinya; Yamaguchi, Hiroya; Yamaoka, Kazutaka; Yamasaki, Noriko Y.; Yamauchi, Makoto; Yamauchi, Shigeo; Yaqoob, Tahir; Yatsu, Yoichi; Yonetoku, Daisuke; Yoshida, Atsumasa; Yuasa, Takayuki; Zhuravleva, Irina; Zoghbi, Abderahmen

    2016-07-06

    Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes1 of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffuse hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling—a process known as active galactic nucleus feedback2, 3, 4, 5, 6. Here we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30–60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. We infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.

  19. CODEX weak lensing: concentration of galaxy clusters at z ˜ 0.5

    Science.gov (United States)

    Cibirka, N.; Cypriano, E. S.; Brimioulle, F.; Gruen, D.; Erben, T.; van Waerbeke, L.; Miller, L.; Finoguenov, A.; Kirkpatrick, C.; Henry, J. Patrick; Rykoff, E.; Rozo, E.; Dupke, R.; Kneib, J.-P.; Shan, H.; Spinelli, P.

    2017-06-01

    We present a stacked weak-lensing analysis of 27 richness selected galaxy clusters at 0.40 ≤ z ≤ 0.62 in the COnstrain Dark Energy with X-ray galaxy clusters (CODEX) survey. The fields were observed in five bands with the Canada-France-Hawaii Telescope (CFHT). We measure the stacked surface mass density profile with a 14σ significance in the radial range 0.1 White profile (NFW) profile and including the off-centring effect. We select the background sample using a conservative colour-magnitude method to reduce the potential systematic errors and contamination by cluster member galaxies. We perform a Bayesian analysis for the stacked profile and constrain the best-fitting NFW parameters M_{200c} = 6.6^{+1.0}_{-0.8} × 10^{14} h^{-1} M_{⊙} and c_{200c} = 3.7^{+0.7}_{-0.6}. The off-centring effect was modelled based on previous observational results found for redMaPPer Sloan Digital Sky Survey clusters. Our constraints on M200c and c200c allow us to investigate the consistency with numerical predictions and select a concentration-mass relation to describe the high richness CODEX sample. Comparing our best-fitting values for M200c and c200c with other observational surveys at different redshifts, we find no evidence for evolution in the concentration-mass relation, though it could be mitigated by particular selection functions. Similar to previous studies investigating the X-ray luminosity-mass relation, our data suggest a lower evolution than expected from self-similarity.

  20. Cytokines and clustered cardiovascular risk factors in children

    DEFF Research Database (Denmark)

    Andersen, Lars Bo; Müller, Klaus; Eiberg, Stig

    2010-01-01

    pronounced in fat and unfit children based on the association with CRP levels. The association between fitness and fatness variables, insulin resistance, and clustered risk could be caused by other mechanisms related to these exposures. The role of IL-6 remains unclear.......The aim was to evaluate the possible role of tumor necrosis factor alpha (TNF-alpha), interleukin-6 (IL-6), C-reactive protein (CRP), low fitness, and fatness in the early development of clustering of cardiovascular disease (CVD) risk factors and insulin resistance. Subjects for this cross......-sectional study were obtained from 18 schools near Copenhagen, Denmark. Two hundred ten 9-year-old children were selected for cytokine analysis from 434 third-grade children with complete CVD risk profiles. The subgroup was selected according to the CVD risk factor profile (upper and lower quartile of a composite...

  1. Improving cluster-based methods for investigating potential for insect pest species establishment: region-specific risk factors

    Directory of Open Access Journals (Sweden)

    Michael J. Watts

    2011-09-01

    Full Text Available Existing cluster-based methods for investigating insect species assemblages or profiles of a region to indicate the risk of new insect pest invasion have a major limitation in that they assign the same species risk factors to each region in a cluster. Clearly regions assigned to the same cluster have different degrees of similarity with respect to their species profile or assemblage. This study addresses this concern by applying weighting factors to the cluster elements used to calculate regional risk factors, thereby producing region-specific risk factors. Using a database of the global distribution of crop insect pest species, we found that we were able to produce highly differentiated region-specific risk factors for insect pests. We did this by weighting cluster elements by their Euclidean distance from the target region. Using this approach meant that risk weightings were derived that were more realistic, as they were specific to the pest profile or species assemblage of each region. This weighting method provides an improved tool for estimating the potential invasion risk posed by exotic species given that they have an opportunity to establish in a target region.

  2. Features of energetic particle radial profiles inferred from geosynchronous responses to solar wind dynamic pressure enhancements

    Directory of Open Access Journals (Sweden)

    Y. Shi

    2009-02-01

    Full Text Available Determination of the radial profile of phase space density of relativistic electrons at constant adiabatic invariants is crucial for identifying the source for them within the outer radiation belt. The commonly used method is to convert flux observed at fixed energy to phase space density at constant first, second and third adiabatic invariants, which requires an empirical global magnetic field model and thus might produce some uncertainties in the final results. From a different perspective, in this paper we indirectly infer the shape of the radial profile of phase space density of relativistic electrons near the geosynchronous region by statistically examining the geosynchronous energetic flux response to 128 solar wind dynamic pressure enhancements during the years 2000 to 2003. We thus avoid the disadvantage of using empirical magnetic field models. Our results show that the flux response is species and energy dependent. For protons and low-energy electrons, the primary response to magnetospheric compression is an increase in flux at geosynchronous orbit. For relativistic electrons, the dominant response is a decrease in flux, which implies that the phase space density decreases toward increasing radial distance at geosynchronous orbit and leads to a local peak inside of geosynchronous orbit. The flux response of protons and non-relativistic electrons could result from a phase density that increases toward increasing radial distance, but this cannot be determined for sure due to the particle energization associated with pressure enhancements. Our results for relativistic electrons are consistent with previous results obtained using magnetic field models, thus providing additional confirmation that these results are correct and indicating that they are not the result of errors in their selected magnetic field model.

  3. Activity Pattern Profiles: Relationship With Affect, Daily Functioning, Impairment, and Variables Related to Life Goals.

    Science.gov (United States)

    Esteve, Rosa; López-Martínez, Alicia E; Peters, Madelon L; Serrano-Ibáñez, Elena R; Ruíz-Párraga, Gema T; González-Gómez, Henar; Ramírez-Maestre, Carmen

    2017-05-01

    The aim of this cross-sectional study was to identify subgroups of patients on the basis of their activity patterns and to investigate their relationship with life goals, optimism, affect, and functioning. The sample was comprised of 276 patients with chronic musculoskeletal pain. Hierarchical cluster analysis was performed on the activity pattern variables and the resulting clusters were compared using 1-way analysis of variance. The 4-cluster was the optimal solution. The 4 clusters comprised: 1) avoiders: patients with high levels of avoidance and low levels of persistence, who use pacing to reduce pain, 2) doers: patients with high levels of persistence and low levels of pacing and avoidance, 3) extreme cyclers: patients with high levels of avoidance and persistence and low levels of pacing, and 4) medium cyclers: patients with moderately high levels of avoidance and persistence and high levels of pacing. Comparison of the clusters showed that doers had the most adaptive profile, whereas avoiders, followed by extreme cyclers, had unhealthy profiles. Doers showed a high level of optimism and a good balance between goal value, expectancy, and conflict. It is useful to distinguish profiles on the basis of various activity patterns. In contrast to profiles characterized by avoidance, profiles characterized by high persistence and low avoidance were associated with adaptive results. Patients with this profile also showed a high level of optimism and a good balance between goal value, expectancy, and conflict. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  4. Dark matter searches with Cherenkov telescopes: nearby dwarf galaxies or local galaxy clusters?

    Energy Technology Data Exchange (ETDEWEB)

    Sánchez-Conde, Miguel A. [SLAC National Laboratory and Kavli Institute for Particle Astrophysics and Cosmology, 2575 Sand Hill Road, Menlo Park, CA 94025 (United States); Cannoni, Mirco; Gómez, Mario E. [Dpto. Física Aplicada, Facultad de Ciencias Experimentales, Universidad de Huelva, 21071 Huelva (Spain); Zandanel, Fabio; Prada, Francisco, E-mail: masc@stanford.edu, E-mail: mirco.cannoni@dfa.uhu.es, E-mail: fabio@iaa.es, E-mail: mario.gomez@dfa.uhu.es, E-mail: fprada@iaa.es [Instituto de Astrofísica de Andalucía (CSIC), E-18008, Granada (Spain)

    2011-12-01

    In this paper, we compare dwarf galaxies and galaxy clusters in order to elucidate which object class is the best target for gamma-ray DM searches with imaging atmospheric Cherenkov telescopes (IACTs). We have built a mixed dwarfs+clusters sample containing some of the most promising nearby dwarf galaxies (Draco, Ursa Minor, Wilman 1 and Segue 1) and local galaxy clusters (Perseus, Coma, Ophiuchus, Virgo, Fornax, NGC 5813 and NGC 5846), and then compute their DM annihilation flux profiles by making use of the latest modeling of their DM density profiles. We also include in our calculations the effect of DM substructure. Willman 1 appears as the best candidate in the sample. However, its mass modeling is still rather uncertain, so probably other candidates with less uncertainties and quite similar fluxes, namely Ursa Minor and Segue 1, might be better options. As for galaxy clusters, Virgo represents the one with the highest flux. However, its large spatial extension can be a serious handicap for IACT observations and posterior data analysis. Yet, other local galaxy cluster candidates with more moderate emission regions, such as Perseus, may represent good alternatives. After comparing dwarfs and clusters, we found that the former exhibit annihilation flux profiles that, at the center, are roughly one order of magnitude higher than those of clusters, although galaxy clusters can yield similar, or even higher, integrated fluxes for the whole object once substructure is taken into account. Even when any of these objects are strictly point-like according to the properties of their annihilation signals, we conclude that dwarf galaxies are best suited for observational strategies based on the search of point-like sources, while galaxy clusters represent best targets for analyses that can deal with rather extended emissions. Finally, we study the detection prospects for present and future IACTs in the framework of the constrained minimal supersymmetric standard model. We

  5. Dark Matter Searches with Cherenkov Telescopes: Nearby Dwarf Galaxies or Local Galaxy Clusters?

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez-Conde, Miguel A.; /KIPAC, Menlo Park /SLAC /IAC, La Laguna /Laguna U., Tenerife; Cannoni, Mirco; /Huelva U.; Zandanel, Fabio; /IAA, Granada; Gomez, Mario E.; /Huelva U.; Prada, Francisco; /IAA, Granada

    2012-06-06

    In this paper, we compare dwarf galaxies and galaxy clusters in order to elucidate which object class is the best target for gamma-ray DM searches with imaging atmospheric Cherenkov telescopes (IACTs). We have built a mixed dwarfs+clusters sample containing some of the most promising nearby dwarf galaxies (Draco, Ursa Minor, Wilman 1 and Segue 1) and local galaxy clusters (Perseus, Coma, Ophiuchus, Virgo, Fornax, NGC 5813 and NGC 5846), and then compute their DM annihilation flux profiles by making use of the latest modeling of their DM density profiles. We also include in our calculations the effect of DM substructure. Willman 1 appears as the best candidate in the sample. However, its mass modeling is still rather uncertain, so probably other candidates with less uncertainties and quite similar fluxes, namely Ursa Minor and Segue 1, might be better options. As for galaxy clusters, Virgo represents the one with the highest flux. However, its large spatial extension can be a serious handicap for IACT observations and posterior data analysis. Yet, other local galaxy cluster candidates with more moderate emission regions, such as Perseus, may represent good alternatives. After comparing dwarfs and clusters, we found that the former exhibit annihilation flux profiles that, at the center, are roughly one order of magnitude higher than those of clusters, although galaxy clusters can yield similar, or even higher, integrated fluxes for the whole object once substructure is taken into account. Even when any of these objects are strictly point-like according to the properties of their annihilation signals, we conclude that dwarf galaxies are best suited for observational strategies based on the search of point-like sources, while galaxy clusters represent best targets for analyses that can deal with rather extended emissions. Finally, we study the detection prospects for present and future IACTs in the framework of the constrained minimal supersymmetric standard model. We

  6. Bright galaxies in the Fornax cluster. Automated galaxy surface photometry: Pt. 7

    International Nuclear Information System (INIS)

    Disney, M.J.; Phillipps, S.; Davies, J.L.; Cawson, M.G.M.; Kibblewhite, E.J.

    1990-01-01

    We have determined surface-brightness profiles for all galaxies down to magnitude B = 16 in the central region of the Fornax cluster. Using existing redshift data, we have determined the distributions of surface brightness for both the whole sample and for cluster disc galaxies only. Although both distributions peak at extrapolated central surface brightness ∼ 21.7B mag/arcsec 2 (the canonical result), it is shown that they are, in fact, consistent with very broad distributions of disc central surface brightness once selection effects and the effects of bulge contamination of the profile are taken into account. (author)

  7. Neutrino dark matter in clusters of galaxies

    International Nuclear Information System (INIS)

    Treumann, R A; Kull, A; Boehringer, H

    2000-01-01

    We present a model calculation for the radial matter density and mass distribution in two clusters of galaxies (Coma and A119) including cold dark matter, massive though light (≅2 eV) neutrino dark matter and collisional intra-cluster gas which emits x-ray radiation. The calculation uses an extension of the Lynden-Bell statistics to the choice of constant masses instead of constant volume. This allows proper inclusion of mixtures of particles of various masses in the gravitational interaction. When it is applied to the matter in the galaxy cluster the radial ROSAT x-ray luminosity profiles can be nicely accounted for. The result is that the statistics identifies the neutrino dark matter in the cluster centre as being degenerate in the sense of Lynden-Bell's spatial degeneracy. This implies that it is distributed in a way different from the classical assumption. The best fits are obtained for the ≅2 eV neutrinos. The fraction of these and their spatial distribution are of interest for understanding cluster dynamics and may have cosmological implications

  8. Neutrino dark matter in clusters of galaxies

    International Nuclear Information System (INIS)

    Treumann, R.A.

    2000-01-01

    We present a model calculation for the radial matter density and mass distribution in two clusters of galaxies (Coma and A119) including cold dark matter, massive though light (approx. 2 eV) neutrino dark matter and collisional intra-cluster gas which emits x-ray radiation. The calculation uses an extension of the Lynden-Bell statistics to the choice of constant masses instead of constant volume. This allows proper inclusion of mixtures of particles of various masses in the gravitational interaction. When it is applied to the matter in the galaxy cluster the radial ROSAT x-ray luminosity profiles can be nicely accounted for. The result is that the statistics identifies the neutrino dark matter in the cluster centre as being degenerate in the sense of Lynden-Bell's spatial degeneracy. This implies that it is distributed in a way different from the classical assumption. The best fits are obtained for the approx. 2 eV neutrinos. The fraction of these and their spatial distribution are of interest for understanding cluster dynamics and may have cosmological implications. (author)

  9. The effects of three-week fasting diet on blood pressure, lipid profile and glucoregulation in extremely obese patients

    Directory of Open Access Journals (Sweden)

    Beleslin Biljana

    2007-01-01

    Full Text Available Introduction Obesity is often accompanied by a number of complications including diabetes mellitus and cardiovascular diseases. Elevated blood pressure and lipids, as well as deterioration of glucoregulation are attributed, as the most significant factors, to development of diabetes mellitus and cardiovascular complications in obese patients. Objective The aim of our study was to evaluate the effects of a fasting diet on blood pressure, lipid profile and glucoregulatory parameters. Method We included 110 patients (33 male and 77 female; mean age 35±1 years, body weight 131.7±2.6 kg, body mass index 45.4±0.8 kg/m2 who were hospitalized for three weeks for the treatment of extreme obesity with the fasting diet. At the beginning, during, and at the end of this period, we evaluated changes in blood pressure, lipid profile, as well as parameters of glucoregulation including glycaemia, insulinaemia, and insulin sensitivity by HOMA. Oral glucose tolerance test (OGTT was performed in all patients at the beginning and at the end of the fasting diet. Results During the fasting diet, the body weight decreased from 131.7±2.6 kg to 117.7±2.4 kg (p<0.001, the body mass index decreased from 45.4±0.8 kg/m2 to 40.8±0.8 kg/m2 (p<0.001, and both systolic and diastolic blood pressure significantly declined (143±2 vs. 132±2 mm Hg, p<0.001; 92±2 vs. 85±2 mm Hg, p<0.001. In addition, the fasting diet produced a significant decrease in total cholesterol, LDL cholesterol, triglycerides, as well as basal glycaemia and insulinaemia (p<0.001 Before the fasting diet, OGTT was normal in 76% of patients, whereas 21% of patients showed glucose intolerance, and 4% of patients diabetes mellitus. After the fasting diet, OGTT was normal in 88% of patients, whereas 12% of patients still had signs of glucose intolerance (p<0.05. In addition, insulin resistance significantly (p<0.05 increased from 54±6% to 89±13% after the fasting diet. Conclusion The three-week fasting

  10. Blood Pressure Control in Hypertensive Patients, Cardiovascular Risk Profile and the Prevalence of Masked Uncontrolled Hypertension (MUCH).

    Science.gov (United States)

    Naser, Nabil; Dzubur, Alen; Durak, Azra; Kulic, Mehmed; Naser, Nura

    2016-07-27

    The term masked hypertension (MH) should be used for untreated individuals who have normal office blood pressure but elevated ambulatory blood pressure. For treated patients, this condition should be termed masked uncontrolled hypertension (MUCH). Masked uncontrolled hypertension (MUCH) has gone unrecognized because few studies have used 24-h ABPM to determine the prevalence of suboptimal BP control in seemingly well-treated patients, and there are few such studies in large cohorts of treated patients attending usual clinical practice. This is important because masked hypertension is associated with a high risk of cardiovascular events. This study was conducted to obtain more information about the association between hypertension and other CV risk factors, about office and ambulatory blood pressure (BP) control as well as on cardiovascular (CV) risk profile in treated hypertensive patients, also to define the prevalence and characteristics of masked uncontrolled hypertension (MUCH) among treated hypertensive patients in routine clinical practice. In this study 2514 male and female patients were included during a period of 5 years follow up. All patients have ambulatory blood pressure monitoring (ABPM) for at least 24h. We identified patients with treated and controlled BP according to current international guidelines (clinic BP, 140/90mmHg). Cardiovascular risk assessment was based on personal history, clinic BP values, as well as target organ damage evaluation. Masked uncontrolled hypertension (MUCH) was diagnosed in these patients if despite controlled clinic BP, the mean 24-h ABPM average remained elevated (24-h systolic BP ≥130mmHg and/or 24-h diastolic BP ≥80mmHg). Patients had a mean age of 60.2+10 years, and the majority of them (94.6%) were followed by specialist physicians. Average clinic BP was 150.4+16/89.9+12 mmHg. About 70% of patients displayed a very high-risk profile. Ambulatory blood pressure monitoring (ABPM) was performed in all recruited

  11. ON THE ACCURACY OF WEAK-LENSING CLUSTER MASS RECONSTRUCTIONS

    International Nuclear Information System (INIS)

    Becker, Matthew R.; Kravtsov, Andrey V.

    2011-01-01

    We study the bias and scatter in mass measurements of galaxy clusters resulting from fitting a spherically symmetric Navarro, Frenk, and White model to the reduced tangential shear profile measured in weak-lensing (WL) observations. The reduced shear profiles are generated for ∼10 4 cluster-sized halos formed in a ΛCDM cosmological N-body simulation of a 1 h -1 Gpc box. In agreement with previous studies, we find that the scatter in the WL masses derived using this fitting method has irreducible contributions from the triaxial shapes of cluster-sized halos and uncorrelated large-scale matter projections along the line of sight. Additionally, we find that correlated large-scale structure within several virial radii of clusters contributes a smaller, but nevertheless significant, amount to the scatter. The intrinsic scatter due to these physical sources is ∼20% for massive clusters and can be as high as ∼30% for group-sized systems. For current, ground-based observations, however, the total scatter should be dominated by shape noise from the background galaxies used to measure the shear. Importantly, we find that WL mass measurements can have a small, ∼5%-10%, but non-negligible amount of bias. Given that WL measurements of cluster masses are a powerful way to calibrate cluster mass-observable relations for precision cosmological constraints, we strongly emphasize that a robust calibration of the bias requires detailed simulations that include more observational effects than we consider here. Such a calibration exercise needs to be carried out for each specific WL mass estimation method, as the details of the method determine in part the expected scatter and bias. We present an iterative method for estimating mass M 500c that can eliminate the bias for analyses of ground-based data.

  12. Rates of collapse and evaporation of globular clusters

    Science.gov (United States)

    Hut, Piet; Djorgovski, S.

    1992-01-01

    Observational estimates of the dynamical relaxation times of Galactic globular clusters are used here to estimate the present rate at which core collapse and evaporation are occurring in them. A core collapse rate of 2 +/- 1 per Gyr is found, which for a Galactic age of about 12 Gyr agrees well with the fact that 27 clusters have surface brightness profiles with the morphology expected for the postcollapse phase. A destruction and evaporation rate of 5 +/- 3 per Gyr is found, suggesting that a significant fraction of the Galaxy's original complement of globular clusters have perished through the combined effects of mechanisms such as relaxation-driven evaporation and shocking due to interaction with the Galactic disk and bulge.

  13. Cardiovascular reactivity patterns and pathways to hypertension: a multivariate cluster analysis

    NARCIS (Netherlands)

    Brindle, R. C.; Ginty, A. T.; Jones, A.; Phillips, A. C.; Roseboom, T. J.; Carroll, D.; Painter, R. C.; de Rooij, S. R.

    2016-01-01

    Substantial evidence links exaggerated mental stress induced blood pressure reactivity to future hypertension, but the results for heart rate reactivity are less clear. For this reason multivariate cluster analysis was carried out to examine the relationship between heart rate and blood pressure

  14. Correlations in Relaxed Clusters of Galaxies

    Directory of Open Access Journals (Sweden)

    Babyk Iu.

    2014-03-01

    Full Text Available The correlations among different quantities in galaxy clusters, observed by Newman et al. (2013a,b, are investigated. We find an anti-correlation among the slope α, the effective radius, Re, and a correlation among the core radius rcore and Re. Moreover, the mass inside 100 kpc (mainly dark matter is correlated with the mass inside 5 kpc (mainly baryons. The listed correlations can be understood in a two phase formation model: the first dissipative phase forming the brightest cluster galaxies, and the second dissipationless phase, in which the inner density profile is flattened by the interaction of baryonic clumps and the dark matter halo through dynamical friction.

  15. THE PLANCK SUNYAEV-ZEL'DOVICH VERSUS THE X-RAY VIEW OF THE COMA CLUSTER

    International Nuclear Information System (INIS)

    Fusco-Femiano, R.; Lapi, A.; Cavaliere, A.

    2013-01-01

    The Planck collaboration has recently published precise and resolved measurements of the Sunyaev-Zel'dovich (SZ) effect in Abell 1656 (the Coma cluster of galaxies), thus directly gauging the electron pressure profile in the intracluster plasma. On the other hand, such a quantity may be also derived from combining the density and temperature provided by X-ray observations of the thermal bremsstrahlung radiation emitted by the plasma. We find a model-independent tension between the SZ and the X-ray pressure, with the SZ one being definitely lower by 15%-20%. We propose that such a challenging tension can be resolved in terms of an additional, non-thermal support to the gravitational equilibrium of the intracluster plasma. This can be straightforwardly included in our Supermodel, so as to fit in detail the Planck SZ profile while being consistent with the X-ray observables. Possible origins of the non-thermal component include cosmic-ray protons, ongoing turbulence, and relativistic electrons; given the existing observational constraints on the first two options, here we focus on the third. For this to be effective, we find that the electron population must include not only an energetic tail accelerated to γ ∼> 10 3 responsible for the Coma radiohalo, but also many more, lower energy electrons. The electron acceleration is to be started by merging events similar to those that provided the very high central entropy of the thermal intracluster plasma in Coma.

  16. Pressure Profiles in a Loop Heat Pipe under Gravity Influence

    Science.gov (United States)

    Ku, Jentung

    2015-01-01

    During the operation of a loop heat pipe (LHP), the viscous flow induces pressure drops in various elements of the loop. The total pressure drop is equal to the sum of pressure drops in vapor grooves, vapor line, condenser, liquid line and primary wick, and is sustained by menisci at liquid and vapor interfaces on the outer surface of the primary wick in the evaporator. The menisci will curve naturally so that the resulting capillary pressure matches the total pressure drop. In ground testing, an additional gravitational pressure head may be present and must be included in the total pressure drop when LHP components are placed in a non-planar configuration. Under gravity-neutral and anti-gravity conditions, the fluid circulation in the LHP is driven solely by the capillary force. With gravity assist, however, the flow circulation can be driven by the combination of capillary and gravitational forces, or by the gravitational force alone. For a gravity-assist LHP at a given elevation between the horizontal condenser and evaporator, there exists a threshold heat load below which the LHP operation is gravity driven and above which the LHP operation is capillary force and gravity co-driven. The gravitational pressure head can have profound effects on the LHP operation, and such effects depend on the elevation, evaporator heat load, and condenser sink temperature. This paper presents a theoretical study on LHP operations under gravity-neutral, anti-gravity, and gravity-assist modes using pressure diagrams to help understand the underlying physical processes. Effects of the condenser configuration on the gravitational pressure head and LHP operation are also discussed.

  17. Reactivity of niobium cluster anions with nitrogen and carbon monoxide

    Science.gov (United States)

    Mwakapumba, Joseph; Ervin, Kent M.

    1997-02-01

    Reactions of small niobium cluster anions, Nbn-(n = 2-7), with CO and N2 are investigated using a flow tube reactor (flowing afterglow) apparatus. Carbon monoxide chemisorption on niobium cluster anions occurs with faster reaction rates than nitrogen chemisorption on corresponding cluster sizes. N2 addition to niobium cluster anions is much more size-selective than is CO addition. These general trends follow those reported in the literature for reactions of neutral and cationic niobium clusters with CO and N2. Extensive fragmentation of the clusters is observed upon chemisorption. A small fraction of the larger clusters survive and sequentially add multiple CO or N2 units without fragmentation. However, chemisorption saturation is not reached at the experimentally accessible pressure and reagent concentration ranges. The thermochemistry of the adsorption processes and the nature of the adsorbed species, molecular or dissociated, are discussed.

  18. Similarity between neonatal profile and socioeconomic index: a spatial approach

    Directory of Open Access Journals (Sweden)

    d'Orsi Eleonora

    2005-01-01

    Full Text Available This study aims to compare neonatal characteristics and socioeconomic conditions in Rio de Janeiro city neighborhoods in order to identify priority areas for intervention. The study design was ecological. Two databases were used: the Brazilian Population Census and the Live Birth Information System, aggregated by neighborhoods. Spatial analysis, multivariate cluster classification, and Moran's I statistics for detection of spatial clustering were used. A similarity index was created to compare socioeconomic clusters with the neonatal profile in each neighborhood. The proportions of Apgar score above 8 and cesarean sections showed positive spatial correlation and high similarity with the socioeconomic index. The proportion of low birth weight infants showed a random spatial distribution, indicating that at this scale of analysis, birth weight is not sufficiently sensitive to discriminate subtler differences among population groups. The observed relationship between the neighborhoods' neonatal profile (particularly Apgar score and mode of delivery and socioeconomic conditions shows evidence of a change in infant health profile, where the possibility for intervention shifts to medical services and the Apgar score assumes growing significance as a risk indicator.

  19. Mass spectrometric production of heterogeneous metal clusters using Knudsen cell

    Directory of Open Access Journals (Sweden)

    Veljković Filip M.

    2016-01-01

    Full Text Available Knudsen effusion mass spectrometry or high-temperature method of mass spectrometry for decades gives new information about saturated vapor of hardly volatile compounds and it is an important method in the discovery of many new molecules, radicals, ions and clusters present in the gas phase. Since pioneering works until now, this method has been successfully applied to a large number of systems (ores, oxides, ceramics, glass materials, borides, carbides, sulfides, nitrates, metals, fullerenes, etc which led to the establishment of various research branches such as chemistry of clusters. This paper describes the basic principles of Knudsen cell use for both identification of chemical species created in the process of evaporation and determination of their ionization energies. Depending on detected ions intensities and the partial pressure of each gaseous component, as well as on changes in partial pressure with temperature, Knudsen cell mass spectrometry enables the determination of thermodynamic parameters of the tested system. A special attention is paid to its application in the field of small heterogeneous and homogeneous clusters of alkali metals. Furthermore, experimental results for thermodynamic parameters of some clusters, as well as capabilities of non-standard ways of using Knudsen cells in the process of synthesis of new clusters are presented herein. [Projekat Ministarstva nauke Republike Srbije, br. 172019

  20. Sun Protection Motivational Stages and Behavior: Skin Cancer Risk Profiles

    Science.gov (United States)

    Pagoto, Sherry L.; McChargue, Dennis E.; Schneider, Kristin; Cook, Jessica Werth

    2004-01-01

    Objective: To create skin cancer risk profiles that could be used to predict sun protection among Midwest beachgoers. Method: Cluster analysis was used with study participants (N=239), who provided information about sun protection motivation and behavior, perceived risk, burn potential, and tan importance. Participants were clustered according to…

  1. Discrimination among individuals using terminal restriction fragment length polymorphism profiling of bacteria derived from forensic evidence.

    Science.gov (United States)

    Nishi, Eiji; Tashiro, Yukihiro; Sakai, Kenji

    2015-05-01

    DNA typing from forensic evidence is commonly used to identify individuals. However, when the quantity of the forensic evidence is insufficient, successful identification using DNA typing is impossible. Such evidence may also contain DNA from bacteria that occur naturally on the skin. In this study, we aimed to establish a profiling method using terminal restriction fragment length polymorphisms (T-RFLPs) of the amplified bacterial 16S ribosomal RNA (rRNA) gene. First, the extraction and digestion processes were investigated, and the T-RFLP profiling method using the 16S rRNA gene amplicon was optimized. We then used this method to compare the profiles of bacterial flora from the hands of 12 different individuals. We found that the T-RFLP profiles from one person on different days displayed higher similarity than those between individuals. In a principal component analysis (PCA), T-RFLPs from each individual were closely clustered in 11 out of 12 cases. The clusters could be distinguished from each other, even when the samples were collected from different conditions. No major change of the profile was observed after six months except in two cases. When handprints on glass plates were compared, 11 of 12 individuals were assigned to a few clusters including the cluster corresponding to the correct individual. In conclusion, a method for reproducible T-RFLP profiling of bacteria from trace amounts of handprints was established. The profiles were obtained for particular individuals clustered in PCA and were experimentally separable from other individuals in most cases. This technique could provide useful information for narrowing down a suspect in a criminal investigation.

  2. ADAPTIVE WEB SITE DENGAN METODE FUZZY CLUSTERING

    Directory of Open Access Journals (Sweden)

    Muchammad Husni

    2004-01-01

    Full Text Available Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Ledakan pertumbuhan dan perkembangan informasi dalam dunia maya menjadikan personalisasian informasi menjadi isu yang penting. Personalisasi informasi yang akan diberikan oleh situs web akan sangat mempengaruhi pola dan perilaku pengguna dalam pencarian informasi, terutama pada perdagangan elektronis (e-commerce. Salah satu pendekatan yang memungkinkan dalam personalisasian web adalah mencari profil pengguna (user profile dari data historis yang sangat besar di file web log. Pengklasifikasian data tanpa pengawasan (unsupervised clasification atau metode metode clustering cukup baik untuk menganalisa data log akses pengguna yang semi terstruktur. Pada metode ini, didefinisikan "user session" dan juga ukuran perbedaan (dissimilarity diantara dua web session yang menggambarkan pengorganisasian sebuah web site. Untuk mendapatkan sebuah profil akses pengguna, dilakukan pembagian user session berdasarkan pasangan ketidaksamaan menggunakan algoritma Fuzzy Clustering. Kata kunci : Adaptive Website, Fuzzy Clustering, personalisasi informasi.

  3. Illuminating the star clusters and satellite galaxies with multi-scale baryonic simulations

    Science.gov (United States)

    Maji, Moupiya; Zhu, Qirong; Li, Yuexing; Marinacci, Federico; Charlton, Jane; Hernquist, Lars; Knebe, Alexander

    2018-01-01

    Over the past decade, advances in computational architecture have made it possible for the first time to investigate some of the fundamental questions around the formation, evolution and assembly of the building blocks of the universe; star clusters and galaxies. In this talk, I will focus on two major questions: What is the origin of the observed universal lognormal mass function in globular clusters? What is the statistical distribution of the properties of satellite planes in a large sample of satellite systems?Observations of globular clusters show that they have universal lognormal mass functions with a characteristic peak at 2X105 MSun, although the origin of this peaked distribution is unclear. We investigate the formation of star clusters in interacting galaxies using baryonic simulations and found that massive clusters preferentially form in extremely high pressure gas clouds which reside in highly shocked regions produced by galaxy interactions. These massive clusters have quasi-lognormal initial mass functions with a peak around ~106MSun which may survive dynamical evolution and slowly evolve into the universal lognormal profiles observed today.The classical Milky Way (MW) satellites are observed to be distributed in a highly-flattened plane, called Disk of Satellites (DoS). However the significance, coherence and origin of DoS is highly debated. To understand this, we first analyze all MW satellites and find that a small sample size can artificially produce a highly anisotropic spatial distribution and a strong clustering of their angular momentum. Comparing a baryonic simulation of a MW-sized galaxy with its N-body counterpart we find that an anisotropic DoS can originate from baryonic processes. Furthermore, we explore the statistical distribution of DoS properties by analyzing 2591 satellite systems in the cosmological hydrodynamic simulation Illustris. We find that the DoS becomes more isotropic with increasing sample sizes and most (~90%) satellite

  4. Generalization of Rindler Potential at Cluster Scales in Randers-Finslerian Spacetime: a Possible Explanation of the Bullet Cluster 1E0657-558?

    Science.gov (United States)

    Chang, Zhe; Li, Ming-Hua; Lin, Hai-Nan; Li, Xin

    2012-12-01

    The data of the Bullet Cluster 1E0657-558 released on November 15, 2006 reveal that the strong and weak gravitational lensing convergence κ-map has an 8σ offset from the Σ-map. The observed Σ-map is a direct measurement of the surface mass density of the Intracluster medium (ICM) gas. It accounts for 83% of the averaged mass-fraction of the system. This suggests a modified gravity theory at large distances different from Newton's inverse-square gravitational law. In this paper, as a cluster scale generalization of Grumiller's modified gravity model (Phys. Rev. Lett.105 (2010) 211303), we present a gravity model with a generalized linear Rindler potential in Randers-Finslerian spacetime without invoking any dark matter. The galactic limit of the model is qualitatively consistent with the MOND and Grumiller's. It yields approximately the flatness of the rotational velocity profile at the radial distance of several kpcs and gives the velocity scales for spiral galaxies at which the curves become flattened. Plots of convergence κ for a galaxy cluster show that the peak of the gravitational potential has chances to lie on the outskirts of the baryonic mass center. Assuming an isotropic and isothermal ICM gas profile with temperature T = 14.8 keV (which is the center value given by observations), we obtain a good match between the dynamical mass MT of the main cluster given by collisionless Boltzmann equation and that given by the King β-model. We also consider a Randers+dark matter scenario and a Λ-CDM model with the NFW dark matter distribution profile. We find that a mass ratio η between dark matter and baryonic matter about 6 fails to reproduce the observed convergence κ-map for the isothermal temperature T taking the observational center value.

  5. Metal cluster cation reactions: Carbon monoxide association to Cu + n ions

    Science.gov (United States)

    Leuchtner, R. E.; Harms, A. C.; Castleman, A. W., Jr.

    1990-06-01

    Copper cluster cations (Cu+n,n=1-14) were produced in a laser vaporization/flow tube apparatus and equilibrated to room temperature. The association rate constants of carbon monoxide onto these ions were measured; low-pressure, termolecular behavior was observed for the smaller species while for clusters greater than Cu+7, the longer lifetimes due to the increased number of degrees of freedom leads to pressure independence (>0.3 Torr) of the effective bimolecular rates. Unimolecular decay theory (RRKM) is used to explain the overall trend and when intrinsic surface site reactivity is taken into account, excellent agreement with measured reactivity is obtained.

  6. Identification of Clusters of Foot Pain Location in a Community Sample.

    Science.gov (United States)

    Gill, Tiffany K; Menz, Hylton B; Landorf, Karl B; Arnold, John B; Taylor, Anne W; Hill, Catherine L

    2017-12-01

    To identify foot pain clusters according to pain location in a community-based sample of the general population. This study analyzed data from the North West Adelaide Health Study. Data were obtained between 2004 and 2006, using computer-assisted telephone interviewing, clinical assessment, and self-completed questionnaire. The location of foot pain was assessed using a diagram during the clinical assessment. Hierarchical cluster analysis was undertaken to identify foot pain location clusters, which were then compared in relation to demographics, comorbidities, and podiatry services utilization. There were 558 participants with foot pain (mean age 54.4 years, 57.5% female). Five clusters were identified: 1 with predominantly arch and ball pain (26.8%), 1 with rearfoot pain (20.9%), 1 with heel pain (13.3%), and 2 with predominantly forefoot, toe, and nail pain (28.3% and 10.7%). Each cluster was distinct in age, sex, and comorbidity profile. Of the two clusters with predominantly forefoot, toe, and nail pain, one of them had a higher proportion of men and those classified as obese, had diabetes mellitus, and used podiatry services (30%), while the other was comprised of a higher proportion of women who were overweight and reported less use of podiatry services (17.5%). Five clusters of foot pain according to pain location were identified, all with distinct age, sex, and comorbidity profiles. These findings may assist in the identification of individuals at risk for developing foot pain and in the development of targeted preventive strategies and treatments. © 2017, American College of Rheumatology.

  7. A Wide-Field Photometric Survey for Extratidal Tails Around Five Metal-Poor Globular Clusters in the Galactic Halo

    Science.gov (United States)

    Chun, Sang-Hyun; Kim, Jae-Woo; Sohn, Sangmo T.; Park, Jang-Hyun; Han, Wonyong; Kim, Ho-Il; Lee, Young-Wook; Lee, Myung Gyoon; Lee, Sang-Gak; Sohn, Young-Jong

    2010-02-01

    Wide-field deep g'r'i' images obtained with the Megacam of the Canada-France-Hawaii Telescope are used to investigate the spatial configuration of stars around five metal-poor globular clusters M15, M30, M53, NGC 5053, and NGC 5466, in a field-of-view ~3°. Applying a mask filtering algorithm to the color-magnitude diagrams of the observed stars, we sorted cluster's member star candidates that are used to examine the characteristics of the spatial stellar distribution surrounding the target clusters. The smoothed surface density maps and the overlaid isodensity contours indicate that all of the five metal-poor globular clusters exhibit strong evidence of extratidal overdensity features over their tidal radii, in the form of extended tidal tails around the clusters. The orientations of the observed extratidal features show signatures of tidal tails tracing the clusters' orbits, inferred from their proper motions, and effects of dynamical interactions with the Galaxy. Our findings include detections of a tidal bridge-like feature and an envelope structure around the pair of globular clusters M53 and NGC 5053. The observed radial surface density profiles of target clusters have a deviation from theoretical King models, for which the profiles show a break at 0.5-0.7rt , extending the overdensity features out to 1.5-2rt . Both radial surface density profiles for different angular sections and azimuthal number density profiles confirm the overdensity features of tidal tails around the five metal-poor globular clusters. Our results add further observational evidence that the observed metal-poor halo globular clusters originate from an accreted satellite system, indicative of the merging scenario of the formation of the Galactic halo. Based on observations carried out at the Canada-France-Hawaii Telescope, operated by the National Research Council of Canada, the Centre National de la Recherche Scientifique de France, and the University of Hawaii. This is part of the

  8. A CHANDRA STUDY OF TEMPERATURE DISTRIBUTIONS OF THE INTRACLUSTER MEDIUM IN 50 GALAXY CLUSTERS

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Zhenghao; Xu, Haiguang; Li, Weitian; Hu, Dan; Zhang, Chenhao; Liu, Chengze [Department of Physics and Astronomy, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang, Shanghai 200240 (China); Wang, Jingying; Gu, Junhua; Wu, Xiang-Ping [National Astronomical Observatories, Chinese Academy of Sciences, 20A Datun Road, Beijing 100012 (China); Gu, Liyi [SRON Netherlands Institute for Space Research, Sorbonnelaan 2, 3584 CA Utrecht (Netherlands); An, Tao [Shanghai Astronomical Observatory, Chinese Academy of Sciences, 80 Nandan Road, Shanghai 200030 (China); Zhang, Zhongli [Max Planck Institute for Astrophysics, Karl-Schwarzschild-Str. 1, Postfach 1317, D-85741 Garching (Germany); Zhu, Jie, E-mail: clsn@sjtu.edu.cn, E-mail: hgxu@sjtu.edu.cn [Department of Electronic Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang, Shanghai 200240 (China)

    2016-01-10

    To investigate the spatial distribution of the intracluster medium temperature in galaxy clusters in a quantitative way and probe the physics behind it, we analyze the X-ray spectra from a sample of 50 clusters that were observed with the Chandra ACIS instrument over the past 15 years and measure the radial temperature profiles out to 0.45r{sub 500}. We construct a physical model that takes into consideration the effects of gravitational heating, thermal history (such as radiative cooling, active galactic nucleus feedback, and thermal conduction), and work done via gas compression, and use it to fit the observed temperature profiles by running Bayesian regressions. The results show that in all cases our model provides an acceptable fit at the 68% confidence level. For further validation, we select nine clusters that have been observed with both Chandra (out to ≳0.3r{sub 500}) and Suzaku (out to ≳1.5r{sub 500}) and fit their Chandra spectra with our model. We then compare the extrapolation of the best fits with the Suzaku measurements and find that the model profiles agree with the Suzaku results very well in seven clusters. In the remaining two clusters the difference between the model and the observation is possibly caused by local thermal substructures. Our study also implies that for most of the clusters the assumption of hydrostatic equilibrium is safe out to at least 0.5r{sub 500} and the non-gravitational interactions between dark matter and its luminous counterparts is consistent with zero.

  9. Clustering of unhealthy lifestyle behaviors is associated with a low adherence to recommended preventive practices among COPD patients in Spain.

    Science.gov (United States)

    de Miguel-Díez, Javier; Jiménez-García, Rodrigo; Hernández-Barrera, Valentín; Maestu, Luis Puente; Aparicio, Irene Jarana; Ramos, Alicia Oliva; López de Andrés, Ana; Carrasco-Garrido, Pilar

    2014-08-01

    To analyze clustering of unhealthy lifestyle behavior and its relationship with non-adherence to recommended clinical preventive care services among Spanish COPD patients. Cross-sectional study including 2,575 COPD subjects from the 2006 Spanish National Health Survey (NHS) and 2009 European Health Survey for Spain (EHISS). Subjects were asked about the following recommended preventive practices: uptake of blood pressure (BP) measurement, lipid profile, influenza vaccination and dental examination. Lifestyle behaviors included: smoking status, physical activity, alcohol consumption and obesity. Logistic regression models were built to assess the association between clustering of unhealthy lifestyle and the uptake of preventive activities. Blood pressure measurement in the previous 6 months and a blood lipid test in the last year had not been taken by 11.74% and 23.26% of the subjects, respectively, in 2006 NHS and by 11.16% and 16.33% of the subjects, respectively, in EHISS 2009. Then, 36.36% percent had not been vaccinated and 70.61% had not received dental examination in 2006 NHS and these percentages decreased to 27.33% and 66.22%, respectively, in 2009 EHISS. A higher number of unhealthy lifestyle behaviors increased the probability of not being vaccinated and not having a dental examination. Clustering of unhealthy lifestyle behaviors is linearly associated with a greater number of preventive measures unfulfilled. Compliance with healthy lifestyles and adherence to recommended clinical preventive services is under desirable levels among Spanish COPD patients. Patients with lifestyles considered as "worse" are those who also have lower uptake of recommended preventive activities.

  10. Using Cluster Analysis and ICP-MS to Identify Groups of Ecstasy Tablets in Sao Paulo State, Brazil.

    Science.gov (United States)

    Maione, Camila; de Oliveira Souza, Vanessa Cristina; Togni, Loraine Rezende; da Costa, José Luiz; Campiglia, Andres Dobal; Barbosa, Fernando; Barbosa, Rommel Melgaço

    2017-11-01

    The variations found in the elemental composition in ecstasy samples result in spectral profiles with useful information for data analysis, and cluster analysis of these profiles can help uncover different categories of the drug. We provide a cluster analysis of ecstasy tablets based on their elemental composition. Twenty-five elements were determined by ICP-MS in tablets apprehended by Sao Paulo's State Police, Brazil. We employ the K-means clustering algorithm along with C4.5 decision tree to help us interpret the clustering results. We found a better number of two clusters within the data, which can refer to the approximated number of sources of the drug which supply the cities of seizures. The C4.5 model was capable of differentiating the ecstasy samples from the two clusters with high prediction accuracy using the leave-one-out cross-validation. The model used only Nd, Ni, and Pb concentration values in the classification of the samples. © 2017 American Academy of Forensic Sciences.

  11. Magnetic diagnostics: General principles and the problem of reconstruction of plasma current and pressure profiles in toroidal systems

    International Nuclear Information System (INIS)

    Pustovitov, V.D.

    2001-01-01

    Restrictions on magnetic diagnostics are discussed. Being related to the integral nature of the measurable quantities, these follow from the fundamental laws of electromagnetism. A series of examples demonstrating the strength of these restrictions is analysed. The general rule is emphasized that information obtained from external magnetic measurements is insufficient for reliable evaluation of plasma current and pressure profiles in tokamaks and in stellarators. The underlying reason is that outside the plasma the self-field of the equilibrium plasma currents is determined by the boundary conditions on the plasma surface alone. (author)

  12. Identification and analysis of evolutionary selection pressures acting at the molecular level in five forkhead subfamilies.

    Science.gov (United States)

    Fetterman, Christina D; Rannala, Bruce; Walter, Michael A

    2008-09-24

    Members of the forkhead gene family act as transcription regulators in biological processes including development and metabolism. The evolution of forkhead genes has not been widely examined and selection pressures at the molecular level influencing subfamily evolution and differentiation have not been explored. Here, in silico methods were used to examine selection pressures acting on the coding sequence of five multi-species FOX protein subfamily clusters; FoxA, FoxD, FoxI, FoxO and FoxP. Application of site models, which estimate overall selection pressures on individual codons throughout the phylogeny, showed that the amino acid changes observed were either neutral or under negative selection. Branch-site models, which allow estimated selection pressures along specified lineages to vary as compared to the remaining phylogeny, identified positive selection along branches leading to the FoxA3 and Protostomia clades in the FoxA cluster and the branch leading to the FoxO3 clade in the FoxO cluster. Residues that may differentiate paralogs were identified in the FoxA and FoxO clusters and residues that differentiate orthologs were identified in the FoxA cluster. Neutral amino acid changes were identified in the forkhead domain of the FoxA, FoxD and FoxP clusters while positive selection was identified in the forkhead domain of the Protostomia lineage of the FoxA cluster. A series of residues under strong negative selection adjacent to the N- and C-termini of the forkhead domain were identified in all clusters analyzed suggesting a new method for refinement of domain boundaries. Extrapolation of domains among cluster members in conjunction with selection pressure information allowed prediction of residue function in the FoxA, FoxO and FoxP clusters and exclusion of known domain function in residues of the FoxA and FoxI clusters. Consideration of selection pressures observed in conjunction with known functional information allowed prediction of residue function and

  13. Molecular profiling of interspecific lowland rice populations derived ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-12-03

    Dec 3, 2008 ... Molecular profiling of interspecific lowland rice populations ... Both cluster and principal component analyses revealed two major groups ...... simulations. Theor ... inheritance, chromosomal location, and population dynamics.

  14. Sound wave generation by a spherically symmetric outburst and AGN feedback in galaxy clusters

    Science.gov (United States)

    Tang, Xiaping; Churazov, Eugene

    2017-07-01

    We consider the evolution of an outburst in a uniform medium under spherical symmetry, having in mind active galactic nucleus feedback in the intracluster medium. For a given density and pressure of the medium, the spatial structure and energy partition at a given time tage (since the onset of the outburst) are fully determined by the total injected energy Einj and the duration tb of the outburst. We are particularly interested in the late phase evolution when the strong shock transforms into a sound wave. We studied the energy partition during such transition with different combinations of Einj and tb. For an instantaneous outburst with tb → 0, which corresponds to the extension of classic Sedov-Taylor solution with counter-pressure, the fraction of energy that can be carried away by sound waves is ≲12 per cent of Einj. As tb increases, the solution approaches the 'slow piston' limit, with the fraction of energy in sound waves approaching zero. We then repeat the simulations using radial density and temperature profiles measured in Perseus and M87/Virgo clusters. We find that the results with a uniform medium broadly reproduce an outburst in more realistic conditions once proper scaling is applied. We also develop techniques to map intrinsic properties of an outburst (Einj, tb and tage) to the observables like the Mach number of the shock and radii of the shock and ejecta. For the Perseus cluster and M87, the estimated (Einj, tb and tage) agree with numerical simulations tailored for these objects with 20-30 per cent accuracy.

  15. KINEMATICS AND EXCITATION OF THE RAM PRESSURE STRIPPED IONIZED GAS FILAMENTS IN THE COMA CLUSTER OF GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Michitoshi [Hiroshima Astrophysical Science Center, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8526 (Japan); Yagi, Masafumi; Komiyama, Yutaka; Kashikawa, Nobunari [Optical and Infrared Astronomy Division, National Astronomical Observatory, Mitaka, Tokyo 181-8588 (Japan); Furusawa, Hisanori [Astronomical Data Center, National Astronomical Observatory of Japan, Mitaka, Tokyo 181-8588 (Japan); Hattori, Takashi [Subaru Telescope, National Astronomical Observatory of Japan, 650 North A' Ohoku Place, Hilo, HI 96720 (United States); Okamura, Sadanori, E-mail: yoshidam@hiroshima-u.ac.jp [Department of Astronomy, University of Tokyo, Tokyo 113-0033 (Japan)

    2012-04-10

    We present the results of deep imaging and spectroscopic observations of very extended ionized gas (EIG) around four member galaxies of the Coma Cluster of galaxies: RB 199, IC 4040, GMP 2923, and GMP 3071. The EIGs were serendipitously found in an H{alpha} narrowband imaging survey of the central region of the Coma Cluster. The relative radial velocities of the EIGs with respect to the systemic velocities of the parent galaxies from which they emanate increase almost monotonically with the distance from the nucleus of the respective galaxies, reaching {approx} - 400 to - 800 km s{sup -1} at around 40-80 kpc from the galaxies. The one-sided morphologies and the velocity fields of the EIGs are consistent with the predictions of numerical simulations of ram pressure stripping. We found a very low velocity filament (v{sub rel} {approx} -1300 km s{sup -1}) at the southeastern edge of the disk of IC 4040. Some bright compact knots in the EIGs of RB 199 and IC 4040 exhibit blue continuum and strong H{alpha} emission. The equivalent widths of the H{alpha} emission exceed 200 A and are greater than 1000 Angstrom-Sign for some knots. The emission-line intensity ratios of the knots are basically consistent with those of sub-solar abundance H II regions. These facts indicate that intensive star formation occurs in the knots. Some filaments, including the low-velocity filament of the IC 4040 EIG, exhibit shock-like emission-line spectra, suggesting that shock heating plays an important role in ionization and excitation of the EIGs.

  16. Health-related fitness profiles in adolescents with complex congenital heart disease

    DEFF Research Database (Denmark)

    Klausen, Susanne Hwiid; Wetterslev, Jørn; Søndergaard, Lars

    2015-01-01

    PURPOSE: This study investigates whether subgroups of different health-related fitness (HrF) profiles exist among girls and boys with complex congenital heart disease (ConHD) and how these are associated with lifestyle behaviors. METHODS: We measured the cardiorespiratory fitness, muscle strength...... in the Robust clusters reported leading a physically active lifestyle and participants in the Less robust cluster reported leading a sedentary lifestyle. Diagnoses were evenly distributed between clusters. CONCLUSIONS: The cluster analysis attributed some of the variability in cardiorespiratory fitness among...

  17. Institutional Profiles: Some Strategic Tools

    Directory of Open Access Journals (Sweden)

    Frans van Vught

    2014-04-01

    Full Text Available In this paper we argue that both internal and external pressures and conditions urge contemporary higher education institutions to carefully think through their institutional profiles positions in domestic and global higher education contexts. We subsequently analyse strategic positioning from the strategic management literature and offer four tools — mapping, multi-dimensional ranking, benchmarking and degree profiling — to assist higher education institutions in their profiling and positioning strategies.

  18. Pressure-induced electrical and magnetic property changes in CaCuMn6O12

    International Nuclear Information System (INIS)

    Zhang, W.; Yao, L.D.; Yang, L.X.; Li, F.Y.; Liu, Z.X.; Jin, C.Q.; Yu, R.C.

    2006-01-01

    CaCuMn 6 O 12 was prepared by using a traditional solid-state reaction method. It is a highly correlated electron system with a small gap appearing at E F and cluster glass state at low temperature, whereas temperature dependence of resistivity suggests that it is related to thermally activated nearest-neighbor hopping in paramagnetism state in higher temperature range. The resistivity decreases with increasing pressure until 11 kbar, and then increases with further increasing pressure. The blocking temperature T b goes down under pressure, indicating the suppression of cluster glass state under pressure

  19. Microbiomes structure and diversity in different horizons of full soil profiles

    Science.gov (United States)

    Chernov, Timofey; Tkhakakhova, Azida; Zhelezova, Alena; Semenov, Mikhail; Kutovaya, Olga

    2017-04-01

    Topsoil is a most common object for soil metagenomic studies; sometimes soil profile is being formally split in layers by depth. However, Russian Soil Science School formulated the idea of soil profile as a complex of soil horizons, which can differ in their properties and genesis. In this research we analyzed 57 genetic soil horizons of 8 different soils from European part of Russia: Albeluvisol, Greyzemic Phaeozem, three Chermozems (different land use - till, fallow, wind-protecting tree line), Rhodic Cambisol, Haplic Kastanozem and Salic Solonetz (WRB classification). Sampling was performed from all genetic horizons in each soil profile starting from topsoil until subsoil. Total DNA was extracted and 16S rRNA sequencing was provided together with chemical analysis of soil (pH measurement, C and N contents, etc.). Structure and diversity of prokaryotic community are significantly different in those soil horizons, which chemical properties and processes of origin are contrasting with nearest horizons: Na-enriched horizon of Solonetz, eluvial horizon of Albeluvisol, plough pan of Agrochernozem. Actinobacteria were abundant in top horizons of soils in warm and dry climate, while Acidobacteria had the highest frequency in soils of moist and cold regions. Concerning Archaea, Thaumarchaeota prevailed in all studied soils. Their rate was higher in microbiomes of upper horizons of steppe soils and it was reducing with depth down the profile. Prokaryotic communities in Chernozems were clustered by soil horizons types: microbiomes of A (organic topsoil) and B (mineral) horizons formed non-overlapping clusters by principal component analysis, cluster formed by prokaryotic communities of transitional soil horizons (AB) take place between clusters of A and B horizons. Moreover, prokaryotic communities of A horizons differ from each other strongly, while microbiomes of B horizons formed a narrow small cluster. It must be explaned by more diverse conditions in upper A horizons

  20. Adolescents' physical activity in physical education, school recess, and extra-curricular sport by motivational profiles.

    Science.gov (United States)

    Mayorga-Vega, Daniel; Viciana, Jesús

    2014-06-01

    The main purpose of this study was to evaluate the differences in adolescents´ objective physical activity levels and perceived effort in physical education, school recess, and extra-curricular organized sport by motivational profiles in physical education. A sample of 102 students 11-16 yr. old completed a self-report questionnaire assessing self-determined motivation toward physical education. Subsequently, students' objective physical activity levels (steps/min., METs, and moderate-to-vigorous physical activity) and perceived effort were evaluated for each situation. Cluster analysis identified a two-cluster structure: "Moderate motivation toward physical education profile" and "High motivation toward physical education profile." Adolescents in the second cluster had higher physical activity and perceived effort values than adolescents in the first cluster, except for METs and moderate-to-vigorous physical activity in extra-curricular sport. These results support the importance of physical education teachers who should promote self-determined motivation toward physical education so that students can reach the recommended physical activity levels.

  1. The relative impact of baryons and cluster shape on weak lensing mass estimates of galaxy clusters

    Science.gov (United States)

    Lee, B. E.; Le Brun, A. M. C.; Haq, M. E.; Deering, N. J.; King, L. J.; Applegate, D.; McCarthy, I. G.

    2018-05-01

    Weak gravitational lensing depends on the integrated mass along the line of sight. Baryons contribute to the mass distribution of galaxy clusters and the resulting mass estimates from lensing analysis. We use the cosmo-OWLS suite of hydrodynamic simulations to investigate the impact of baryonic processes on the bias and scatter of weak lensing mass estimates of clusters. These estimates are obtained by fitting NFW profiles to mock data using MCMC techniques. In particular, we examine the difference in estimates between dark matter-only runs and those including various prescriptions for baryonic physics. We find no significant difference in the mass bias when baryonic physics is included, though the overall mass estimates are suppressed when feedback from AGN is included. For lowest-mass systems for which a reliable mass can be obtained (M200 ≈ 2 × 1014M⊙), we find a bias of ≈-10 per cent. The magnitude of the bias tends to decrease for higher mass clusters, consistent with no bias for the most massive clusters which have masses comparable to those found in the CLASH and HFF samples. For the lowest mass clusters, the mass bias is particularly sensitive to the fit radii and the limits placed on the concentration prior, rendering reliable mass estimates difficult. The scatter in mass estimates between the dark matter-only and the various baryonic runs is less than between different projections of individual clusters, highlighting the importance of triaxiality.

  2. Mechanical breath profile of airway pressure release ventilation: the effect on alveolar recruitment and microstrain in acute lung injury.

    Science.gov (United States)

    Kollisch-Singule, Michaela; Emr, Bryanna; Smith, Bradford; Roy, Shreyas; Jain, Sumeet; Satalin, Joshua; Snyder, Kathy; Andrews, Penny; Habashi, Nader; Bates, Jason; Marx, William; Nieman, Gary; Gatto, Louis A

    2014-11-01

    Improper mechanical ventilation settings can exacerbate acute lung injury by causing a secondary ventilator-induced lung injury. It is therefore important to establish the mechanism by which the ventilator induces lung injury to develop protective ventilation strategies. It has been postulated that the mechanism of ventilator-induced lung injury is the result of heterogeneous, elevated strain on the pulmonary parenchyma. Acute lung injury has been associated with increases in whole-lung macrostrain, which is correlated with increased pathology. However, the effect of mechanical ventilation on alveolar microstrain remains unknown. To examine whether the mechanical breath profile of airway pressure release ventilation (APRV), consisting of a prolonged pressure-time profile and brief expiratory release phase, reduces microstrain. In a randomized, nonblinded laboratory animal study, rats were randomized into a controlled mandatory ventilation group (n = 3) and an APRV group (n = 3). Lung injury was induced by polysorbate lavage. A thoracotomy was performed and an in vivo microscope was placed on the lungs to measure alveolar mechanics. In the controlled mandatory ventilation group, multiple levels of positive end-expiratory pressure (PEEP; 5, 10, 16, 20, and 24 cm H2O) were tested. In the APRV group, decreasing durations of expiratory release (time at low pressure [T(low)]) were tested. The T(low) was set to achieve ratios of termination of peak expiratory flow rate (T-PEFR) to peak expiratory flow rate (PEFR) of 10%, 25%, 50%, and 75% (the smaller this ratio is [ie, 10%], the more time the lung is exposed to low pressure during the release phase, which decreases end-expiratory lung volume and potentiates derecruitment). Alveolar perimeters were measured at peak inspiration and end expiration using digital image analysis, and strain was calculated by normalizing the change in alveolar perimeter length to the original length. Macrostrain was measured by volume

  3. Observation of propane cluster size distributions during nucleation and growth in a Laval expansion

    Energy Technology Data Exchange (ETDEWEB)

    Ferreiro, Jorge J.; Chakrabarty, Satrajit; Schläppi, Bernhard; Signorell, Ruth [Laboratory of Physical Chemistry, ETH Zürich, Vladimir-Prelog Weg 2, CH-8093 Zürich (Switzerland)

    2016-12-07

    We report on molecular-level studies of the condensation of propane gas and propane/ethane gas mixtures in the uniform (constant pressure and temperature) postnozzle flow of Laval expansions using soft single-photon ionization by vacuum ultraviolet light and mass spectrometric detection. The whole process, from the nucleation to the growth to molecular aggregates of sizes of several nanometers (∼5 nm), can be monitored at the molecular level with high time-resolution (∼3 μs) for a broad range of pressures and temperatures. For each time, pressure, and temperature, a whole mass spectrum is recorded, which allows one to determine the critical cluster size range for nucleation as well as the kinetics and mechanisms of cluster-size specific growth. The detailed information about the size, composition, and population of individual molecular clusters upon condensation provides unique experimental data for comparison with future molecular-level simulations.

  4. Healthcare managers' leadership profiles in relation to perceptions of work stressors and stress.

    Science.gov (United States)

    Lornudd, Caroline; Bergman, David; Sandahl, Christer; von Thiele Schwarz, Ulrica

    2016-05-03

    Purpose The purpose of this study is to investigate the relationship between leadership profiles and differences in managers' own levels of work stress symptoms and perceptions of work stressors causing stress. Design/methodology/approach Cross-sectional data were used. Healthcare managers ( n = 188) rated three dimensions of their leadership behavior and levels of work stressors and stress. Hierarchical cluster analysis was performed to identify leadership profiles based on leadership behaviors. Differences in stress-related outcomes between profiles were assessed using one-way analysis of variance. Findings Four distinct clusters of leadership profiles were found. They discriminated in perception of work stressors and stress: the profile distinguished by the lowest mean in all behavior dimensions, exhibited a pattern with significantly more negative ratings compared to the other profiles. Practical implications This paper proposes that leadership profile is an individual factor involved in the stress process, including work stressors and stress, which may inform targeted health promoting interventions for healthcare managers. Originality/value This is the first study to investigate the relationship between leadership profiles and work stressors and stress in healthcare managers.

  5. Explosions of water clusters in intense laser fields

    International Nuclear Information System (INIS)

    Kumarappan, V.; Krishnamurthy, M.; Mathur, D.

    2003-01-01

    Energetic, highly charged oxygen ions O q+ (q≤6), are copiously produced upon laser field-induced disassembly of highly charged water clusters, (H 2 O) n and (D 2 O) n , n∼60, that are formed by seeding high-pressure helium or argon with water vapor. Ar n clusters (n∼40 000) formed under similar experimental conditions are found to undergo disassembly in the Coulomb explosion regime, with the energies of Ar q+ ions showing a q 2 dependence. Water clusters, which are argued to be considerably smaller in size, should also disassemble in the same regime, but the energies of fragment O q+ ions are found to depend linearly on q which, according to prevailing wisdom, ought to be a signature of hydrodynamic expansion that is expected of much larger clusters. The implication of these observations on our understanding of the two cluster explosion regimes, Coulomb explosion and hydrodynamic expansion, is discussed. Our results indicate that charge state dependences of ion energy do not constitute an unambiguous experimental signature of cluster explosion regime

  6. Targeted Serum Metabolite Profiling Identifies Metabolic Signatures in Patients with Alzheimer's Disease, Normal Pressure Hydrocephalus and Brain Tumor

    Directory of Open Access Journals (Sweden)

    Matej Orešič

    2018-01-01

    Full Text Available Progression to AD is preceded by elevated levels of 2,4-dihydroxybutanoic acid (2,4-DHB, implicating hypoxia in early pathogenesis. Since hypoxia may play a role in multiple CNS disorders, we investigated serum metabolite profiles across three disorders, AD, Normal Pressure Hydrocephalus (NPH and brain tumors (BT. Blood samples were collected from 27 NPH and 20 BT patients. The profiles of 21 metabolites were examined. Additionally, data from 37 AD patients and 46 controls from a previous study were analyzed together with the newly acquired data. No differences in 2,4-DHB were found across AD, NPH and BT samples. In the BT group, the fatty acids were increased as compared to HC and NPH groups, while the ketone body 3-hydroxybutyrate was increased as compared to AD. Glutamic acid was increased in AD as compared to the HC group. In the AD group, 3-hydroxybutyrate tended to be decreased with respect to all other groups (mean values −30% or more, but the differences were not statistically significant. Serine was increased in NPH as compared to BT. In conclusion, AD, NPH and BT have different metabolic profiles. This preliminary study may help in identifying the blood based markers that are specific to these three CNS diseases.

  7. Tidal stripping stellar substructures around four metal-poor globular clusters in the galactic bulge

    International Nuclear Information System (INIS)

    Chun, Sang-Hyun; Kang, Minhee; Jung, DooSeok; Sohn, Young-Jong

    2015-01-01

    We investigate the spatial density configuration of stars around four metal-poor globular clusters (NGC 6266, NGC 6626, NGC 6642, and NGC 6723) in the Galactic bulge region using wide-field deep J, H, and K imaging data obtained with the Wide Field Camera near-infrared array on the United Kingdom Infrared Telescope. A statistical weighted filtering algorithm for the stars on the color–magnitude diagram is applied in order to sort cluster member candidates from the field star contamination. In two-dimensional isodensity contour maps of the clusters, we find that all four of the globular clusters exhibit strong evidence of tidally stripped stellar features beyond the tidal radius in the form of tidal tails or small density lobes/chunks. The orientations of the extended stellar substructures are likely to be associated with the effect of dynamic interaction with the Galaxy and the cluster's space motion. The observed radial density profiles of the four globular clusters also describe the extended substructures; they depart from theoretical King and Wilson models and have an overdensity feature with a break in the slope of the profile at the outer region of clusters. The observed results could imply that four globular clusters in the Galactic bulge region have experienced strong environmental effects such as tidal forces or bulge/disk shocks of the Galaxy during the dynamical evolution of globular clusters. These observational results provide further details which add to our understanding of the evolution of clusters in the Galactic bulge region as well as the formation of the Galaxy.

  8. Segmentation of Residential Gas Consumers Using Clustering Analysis

    Directory of Open Access Journals (Sweden)

    Marta P. Fernandes

    2017-12-01

    Full Text Available The growing environmental concerns and liberalization of energy markets have resulted in an increased competition between utilities and a strong focus on efficiency. To develop new energy efficiency measures and optimize operations, utilities seek new market-related insights and customer engagement strategies. This paper proposes a clustering-based methodology to define the segmentation of residential gas consumers. The segments of gas consumers are obtained through a detailed clustering analysis using smart metering data. Insights are derived from the segmentation, where the segments result from the clustering process and are characterized based on the consumption profiles, as well as according to information regarding consumers’ socio-economic and household key features. The study is based on a sample of approximately one thousand households over one year. The representative load profiles of consumers are essentially characterized by two evident consumption peaks, one in the morning and the other in the evening, and an off-peak consumption. Significant insights can be derived from this methodology regarding typical consumption curves of the different segments of consumers in the population. This knowledge can assist energy utilities and policy makers in the development of consumer engagement strategies, demand forecasting tools and in the design of more sophisticated tariff systems.

  9. HEART RATE VARIABILITY PARAMETERS IN PATIENTS WITH ARTERIAL HYPERTENSION IN DEPENDENCE ON THE TYPE OF DAILY BLOOD PRESSURE PROFILE

    Directory of Open Access Journals (Sweden)

    S. G. B. K. Gorantla

    2017-06-01

    Full Text Available Violation of functioning of the autonomic nervous system is an important factor in the formation and progression of arterial hypertension (AH. Abnormal nocturnal blood pressure (BP reduction is regarded as an independent prognostic factor for cardiovascular complications in patients with AH. One of the possible factors that determine the violation of BP circadian rhythm can be imbalance of different parts of autonomic nervous system. The aim of our study was to study heart rate variability (HRV in patients with AH, dependently of BP profile. 72 patients with AH were examined. Average age was 57 ± 11 years. All patients underwent ambulatory BP (ABPM and ECG monitoring. To define the daily profile the nocturnal BP dip was quantified and for HRV evaluation the frequency analysis method was used. HRV changes in patients with AH present with reduced total power and with a violation in the ratio of the powers of very low, low and high frequencies, enhanced sympathycotension and influence of humoral factors. Violations of systolic BP (SBP daily profile was mainly characterized by an increase in the power of low frequency waves, which indicates an intensification of sympathetic and decreased parasympathetic influences. Violations of diastolic BP (DBP daily profile were mainly characterized by a relative increase in the power of very low frequency waves. The obtained results showed that in the management of patients with AH it is important not only to control the circadian SBP and DBP profiles, but the evaluation of HRV also.

  10. A cluster-analytic profiling of heroin-dependent patients based on level, clinical adequacy, and patient-desired adjustment of buprenorphine dosage during buprenorphine-naloxone maintenance treatment in sixteen Spanish centers.

    Science.gov (United States)

    Alcaraz, Saul; González-Saiz, Francisco; Trujols, Joan; Vergara-Moragues, Esperanza; Siñol, Núria; Pérez de Los Cobos, José

    2018-06-01

    Buprenorphine dosage is a crucial factor influencing outcomes of buprenorphine treatment for heroin use disorders. Therefore, the aim of the present study is to identify naturally occurring profiles of heroin-dependent patients regarding individualized management of buprenorphine dosage in clinical practice of buprenorphine-naloxone maintenance treatment. 316 patients receiving buprenorphine-naloxone maintenance treatment were surveyed at 16 Spanish centers during the stabilization phase of this treatment. Patients were grouped using cluster analysis based on three key indicators of buprenorphine dosage management: dose, adequacy according to physician, and adjustment according to patient. The clusters obtained were compared regarding different facets of patient clinical condition. Four clusters were identified and labeled as follows (buprenorphine average dose and percentage of participants in each cluster are given in brackets): "Clinically Adequate and Adjusted to Patient Desired Low Dosage" (2.60 mg/d, 37.05%); "Clinically Adequate and Adjusted to Patient Desired High Dosage" (10.71 mg/d, 29.18%); "Clinically Adequate and Patient Desired Reduction of Low Dosage" (3.38 mg/d, 20.0%); and "Clinically Inadequate and Adjusted to Patient Desired Moderate Dosage" (7.55 mg/d, 13.77%). Compared to patients from the other three clusters, participants in the latter cluster reported more frequent use of heroin and cocaine during last week, lower satisfaction with buprenorphine-naloxone as a medication, higher prevalence of buprenorphine-naloxone adverse effects and poorer psychological adjustment. Our results show notable differences between clusters of heroin-dependent patients regarding buprenorphine dosage management. We also identified a group of patients receiving clinically inadequate buprenorphine dosage, which was related to poorer clinical condition. Copyright © 2018 Elsevier B.V. All rights reserved.

  11. Cognitive profiles of three clusters of patients with a first-episode psychosis.

    Science.gov (United States)

    Ochoa, Susana; Huerta-Ramos, Elena; Barajas, Ana; Iniesta, Raquel; Dolz, Montserrat; Baños, Iris; Sánchez, Bernardo; Carlson, Janina; Foix, Alexandrina; Pelaez, Trinidad; Coromina, Marta; Pardo, Marta; Usall, Judith

    2013-10-01

    The primary objective was to identify specific groups of patients with a first-episode psychosis based on family history, obstetric complications, neurological soft signs, and premorbid functioning. The secondary objective was to relate these groups with cognitive variables. A total of 62 first-episode psychoses were recruited from adult and child and adolescent mental health services. The inclusion criteria were patients between 7 and 65 years old (real range of the samples was 13-35 years old), two or more psychotic symptoms and less than one year from the onset of the symptoms. Premorbid functioning (PAS), soft signs (NES), obstetric complications and a neuropsychological battery (CPT, TMTA/TMTB, TAVEC/TAVECI, Stroop, specific subtest of WAIS-III/WISC-IV) were administered. We found three clusters: 1) higher neurodevelopment contribution (N=14), 2) higher genetic contribution (N=30), and 3) lower neurodevelopment contribution (N=18). Statistical differences were found between groups in TMTB, learning curve of the TAVEC, digits of the WAIS and premorbid estimated IQ, the cluster 1 being the most impaired. A cluster approach could differentiate several groups of patients with different cognitive performance. Neuropsychological interventions, as cognitive remediation, should be addressed specifically to patients with more impaired results. © 2013 Elsevier B.V. All rights reserved.

  12. Análise de conglomerados em curvas de aprendizado para formação de agrupamentos homogêneos de trabalhadores Cluster analysis of learning curves for grouping workers with homogeneous learning profiles

    Directory of Open Access Journals (Sweden)

    Renato Eduardo Stroieke

    2012-01-01

    Full Text Available Em diversos setores da indústria é desejado que trabalhadores reunidos em uma estação de trabalho apresentem perfil de aprendizado similar. O presente artigo apresenta um método de agrupamento de trabalhadores utilizando modelagem por curva de aprendizado e técnicas de clusterização. O método modela dados de desempenho de trabalhadores por intermédio de diversos modelos de curvas de aprendizado; os parâmetros de aprendizado dos modelos testados permitem predizer o desempenho dos trabalhadores em intervalos de tempo pré-determinados. Os valores preditos são agrupados através de ferramentas de clusterização. O maior índice de ajuste (IA, gerado a partir do Silhouette Index e do coeficiente de determinação, indica o modelo de curva mais consistente em termos de aderência aos dados e qualidade de agrupamento de perfis de aprendizado. Ao ser aplicado em dados de uma indústria de calçados, o método gerou agrupamentos consistentes de trabalhadores com base nos distintos perfis de aprendizado.In many industrial segments, it is desirable to allocate workers with similar learning profiles in the same workstation. This paper presents a method that groups workers based on learning curve modeling and clustering techniques. Workers' performance data are modeled through several learning curve models; learning parameters allow for workers' performance prediction at intervals of predetermined time. The predicted values are then grouped by clustering techniques. The largest Adjustment Index (AI, derived from the Silhouette Index and Coefficient of Determination, indicates the model yielding superior adherence to data and better clustering of learning profiles. When applied to a shoe manufacturing process, the method generated consistent groups of workers based on their learning profiles.

  13. Tongue pressure profile training for dysphagia post stroke (TPPT): study protocol for an exploratory randomized controlled trial.

    Science.gov (United States)

    Steele, Catriona M; Bayley, Mark A; Péladeau-Pigeon, Melanie; Stokely, Shauna L

    2013-05-07

    It is estimated that approximately 50% of stroke survivors will experience swallowing difficulty, or dysphagia. The associated sequelae of dysphagia include dehydration, malnutrition, and aspiration pneumonia, all of which have can have serious medical consequences. To improve swallowing safety and efficiency, alternative nutritional intake methods (for example, a feeding tube) or a modified diet texture (such as pureed foods or thickened liquids) may be recommended but these modifications may negatively affect quality of life. An alternative approach to treating dysphagia has emerged over the past few years, targeting stronger lingual muscles through maximal isometric pressure tasks. Although these studies have shown promising results, thin-liquid bolus control continues to be challenging for patients with dysphagia. Previous work investigating lingual pressures when healthy participants swallow has suggested that greater task specificity in lingual exercises may yield improved results with thin liquids. This is a small, exploratory randomized clinical trial being conducted with post-stroke patients 4 to 20 weeks after onset of dysphagia secondary to impaired lingual control. At enrollment, participants are randomly assigned to one of two treatment protocols, either tongue pressure profile training (TPPT) or the control treatment, tongue pressure strength-and-accuracy training (TPSAT). Each treatment protocol consists of 24 sessions of treatment over 8 to 12 weeks with monitoring of tongue pressure as well as a baseline and outcome videofluoroscopic swallowing study. Tongue pressure measures, videofluoroscopic measures, and functional outcome measures will be obtained following training of 60 participants (30 in each condition), to determine whether TPPT yields better outcomes. This study will continue to explore options beyond tube feeding and modified diets for people with neurogenic dysphagia following stroke. Should the novel protocol, TPPT, prove to be more

  14. A new Be star in an open cluster - NGC 6871-8

    Science.gov (United States)

    Grigsby, James A.; Morrison, Nancy D.

    1988-01-01

    Spectroscopic observations of H-alpha show that star eight in the open cluster NGC 6871 is a previously-undiscovered Be star. The H-alpha profile was observed to vary from clear emission to pure absorption over a period of ten days; later observations over a five-day interval show weak emission along with asymmetries and filling in of the profile.

  15. A latent profile analysis of Asian American men's and women's adherence to cultural values.

    Science.gov (United States)

    Wong, Y Joel; Nguyen, Chi P; Wang, Shu-Yi; Chen, Weilin; Steinfeldt, Jesse A; Kim, Bryan S K

    2012-07-01

    The goal of this study was to identify diverse profiles of Asian American women's and men's adherence to values that are salient in Asian cultures (i.e., conformity to norms, family recognition through achievement, emotional self-control, collectivism, and humility). To this end, the authors conducted a latent profile analysis using the 5 subscales of the Asian American Values Scale-Multidimensional in a sample of 214 Asian Americans. The analysis uncovered a four-cluster solution. In general, Clusters 1 and 2 were characterized by relatively low and moderate levels of adherence to the 5 dimensions of cultural values, respectively. Cluster 3 was characterized by the highest level of adherence to the cultural value of family recognition through achievement, whereas Cluster 4 was typified by the highest levels of adherence to collectivism, emotional self-control, and humility. Clusters 3 and 4 were associated with higher levels of depressive symptoms than Cluster 1. Furthermore, Asian American women and Asian American men had lower odds of being in Cluster 4 and Cluster 3, respectively. These findings attest to the importance of identifying specific patterns of adherence to cultural values when examining the relationship between Asian Americans' cultural orientation and mental health status.

  16. Core level photoelectron spectroscopy probed heterogeneous xenon/neon clusters

    International Nuclear Information System (INIS)

    Pokapanich, Wandared; Björneholm, Olle; Öhrwall, Gunnar; Tchaplyguine, Maxim

    2017-01-01

    Binary rare gas clusters; xenon and neon which have a significant contrariety between sizes, produced by a co-expansion set up and have been studied using synchrotron radiation based x-ray photoelectron spectroscopy. Concentration ratios of the heterogeneous clusters; 1%, 3%, 5% and 10% were controlled. The core level spectra were used to determine structure of the mixed cluster and analyzed by considering screening mechanisms. Furthermore, electron binding energy shift calculations demonstrated cluster aggregation models which may occur in such process. The results showed that in the case of low mixing ratios of 3% and 5% of xenon in neon, the geometric structures exhibit xenon in the center and xenon/neon interfaced in the outer shells. However, neon cluster vanished when the concentration of xenon was increased to 10%. - Highlights: • Co-expansion setup is suitable for producing binary Xe/Ne clusters. • Appropriate temperature, pressure, and mixing ratios should be strictly controlled. • Low mixing ratio, Xe formed in the core and Xe/Ne interfacing in the outer shell. • High mixing ratio, only pure Xe clusters were detected.

  17. Surface processing with ionized cluster beams: computer simulation

    International Nuclear Information System (INIS)

    Insepov, Z.; Yamada, I.

    1999-01-01

    Molecular Dynamics (MD) and Monte Carlo (MC) models of energetic gas cluster irradiation of a solid surface have been developed to investigate the phenomena of crater formation, sputtering, surface treatment, and the material hardness evaluation by irradiation with cluster ions. Theoretical estimation of crater dimensions formed with Ar gas cluster ion irradiation of different substrates, based on hydrodynamics and MD simulation, are presented. The atomic scale shock waves arising from cluster impact were obtained by calculating the pressure, temperature and mass-velocity of the target atoms. The crater depth is given as a unique 1/3 dependence on the cluster energy and on the cold material Brinell hardness number (BHN). A new 'true material hardness' scale which can be very useful for example for thin film coatings deposited on a soft substrate, is defined. This finding could be used as a new technique for measuring of a material hardness. Evolution of surface morphology under cluster ion irradiation was described by the surface relaxation equation which contains a term of crater formation at cluster impact. The formation of ripples on a surface irradiated with oblique cluster ion beams was predicted. MD and MC models of Decaborane ion (B 10 H 14 ) implantation into Si and the following rapid thermal annealing (RTA) have been developed

  18. The far from equilibrium structure of argon clusters doped with krypton or xenon.

    Science.gov (United States)

    Lindblad, A; Bergersen, H; Rander, T; Lundwall, M; Ohrwall, G; Tchaplyguine, M; Svensson, S; Björneholm, O

    2006-04-28

    Heterogeneous clusters created by doping Ar host clusters with Kr or Xe are shown to have radically different structures from the mixed clusters of the same type created by co-expansion of Ar-Kr or Ar-Xe gas mixtures. In contrast to the co-expansion case, the doped mixed clusters can be produced with Kr or Xe on the surface and Ar in the bulk. With the doping technique it is thus possible to control the surface composition of a specific cluster. A study of the cluster properties as a function of the doping pressure is also reported for the case of Ar clusters doped with Xe. The clusters have been studied by means of synchrotron radiation based X-ray photoelectron spectroscopy.

  19. Cardiovascular disease risk factor clustering among rural adult population in West Bengal, India.

    Science.gov (United States)

    Nag, Tanmay; Ghosh, Arnab

    2016-01-01

    This study aimed to find out the prevalence of cardiovascular disease (CVD) risk factor clustering in a rural adult population of West Bengal, India. This cross-sectional study was carried out among 1007 participants (645 males and 362 females) aged ≥20 years in a rural community. All participants were grouped: Group I (20-39 years); Group II (40-59 years); Group III (≥60 years). Anthropometric measures were collected using standard techniques. Metabolic profiles and blood pressure were also measured. Mean of minimum waist circumference (MWC), waist-hip ratio (WHR), trunk-extremity ratio (TER), fat free mass (FFM), basal metabolic rate (BMR), intra-abdominal visceral fat (IVF) and arm muscle area (AMA) was found to be higher among males in comparison to females, whereas, the mean of body mass index (BMI), maximum hip circumference (MHC), waist-height ratio (WHtR), sum of four skinfolds (∑SF4), percentage of body fat (%BF), fat mass (FM), insulin, HOMA-IR and arm fat area (AFA) was higher in females. 37% of individuals (males 25% and females 49%) with high triglyceride (TG) also had low high density lipoprotein (HDL), whereas, 25% individuals (males 25% and females 24%) with overweight also had high fasting blood glucose (FBG). The prevalence of high systolic blood pressure (SBP) among individuals having high %BF was higher in the age groups of 40-59 years for both sexes. The study showed that prevalence of CVD risk factor clustering is high in the study population and warranted early intervention to safeguard the cardiovascular health of the nation. Copyright © 2015 Asia Oceania Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

  20. Global aphasia without hemiparesis: language profiles and lesion distribution

    Science.gov (United States)

    Hanlon, R.; Lux, W.; Dromerick, A.

    1999-01-01

    OBJECTIVES—Global aphasia without hemiparesis (GAWH) is an uncommon stroke syndrome involving receptive and expressive language impairment, without the hemiparesis typically manifested by patients with global aphasia after large left perisylvian lesions. A few cases of GAWH have been reported with conflicting conclusions regarding pathogenesis, lesion localisation, and recovery. The current study was conducted to attempt to clarify these issues.
METHODS—Ten cases of GAWH were prospectively studied with language profiles and lesion analysis; five patients had multiple lesions, four patients had a single lesion, and one had a subarachnoid haemorrhage. Eight patients met criteria for cardioembolic ischaemic stroke.
RESULTS—Cluster analysis based on acute language profiles disclosed three subtypes of patients with GAWH; these clusters persisted on follow up language assessment. Each cluster evolved into a different aphasia subtype: persistent GAWH, Wernicke's aphasia, or transcortical motor aphasia (TCM). Composite lesion analysis showed that persistent GAWH was related to lesioning of the left superior temporal gyrus. Patients with acute GAWH who evolved into TCM type aphasia had common lesioning of the left inferior frontal gyrus and adjacent subcortical white matter. Patients with acute GAWH who evolved into Wernicke's type aphasia were characterised by lesioning of the left precentral and postcentral gyri. Recovery of language was poor in all but one patient.
CONCLUSIONS—Although patients with acute GAWH are similar on neurological examination, they are heterogeneous with respect to early aphasia profile, language recovery, and lesion profile.

 PMID:10084536

  1. Calibration and Process of Signal of Photomultiplier Tube in Rayleigh Scattering of Supersonic Jet Clusters

    International Nuclear Information System (INIS)

    Lu Jianfeng; Liu Meng; Han Jifeng; Li Jia; Luo Xiaobing; Miao Jingwei; Yang Chaowen

    2009-01-01

    In the experiments of Rayleigh scattering of gas-jet clusters, the signal amplitude of PMT is not only affected by duster itself, but also by the intensity of light source and work voltage of PMT. When the back pressure of cluster source varies from 10 atm to about 100atm, the signal amplitude of PMT may be from linear to nonlinear. In order to solve the problem, signal calibration of PMT under different intensifies of light and voltage of PMT has been done. The relationship between the amplitude of signal and intensities of light as well as voltage of PMT has been obtained. The function of scatter factor of Ar clusters with the back pressure of cluster source is gotten experimentally, and agrees with related experimental and theoretical results. (authors)

  2. RADIAL VELOCITIES FROM VLT-KMOS SPECTRA OF GIANT STARS IN THE GLOBULAR CLUSTER NGC 6388

    International Nuclear Information System (INIS)

    Lapenna, E.; Mucciarelli, A.; Lanzoni, B.; Ferraro, F. R.; Dalessandro, E.; Origlia, L.; Valenti, E.; Cirasuolo, M.

    2015-01-01

    We present new radial velocity measurements for 82 stars, members of the Galactic globular cluster (GC) NGC 6388, obtained from ESO-VLT K-band Multi Object Spectrograph (KMOS) spectra acquired during the instrument Science Verification. The accuracy of the wavelength calibration is discussed and a number of tests of the KMOS response are presented. The cluster systemic velocity obtained (81.3 ± 1.5 km s –1 ) is in very good agreement with previous determinations. While a hint of ordered rotation is found between 9'' and 20'' from the cluster center, where the distribution of radial velocities is clearly bimodal, more data are needed before drawing any firm conclusions. The acquired sample of radial velocities has also been used to determine the cluster velocity dispersion (VD) profile between ∼9'' and 70'', supplementing previous measurements at r < 2'' and r > 60'' obtained with ESO-SINFONI and ESO-FLAMES spectroscopy, respectively. The new portion of the VD profile nicely matches the previous ones, better defining the knee of the distribution. The present work clearly shows the effectiveness of a deployable integral field unit in measuring the radial velocities of individual stars for determining the VD profile of Galactic GCs. It represents the pilot project for an ongoing large program with KMOS and FLAMES at the ESO-VLT, aimed at determining the next generation of VD and rotation profiles for a representative sample of GCs

  3. VizieR Online Data Catalog: Tidal radii of 7 globular clusters (Lehmann+ 1997)

    Science.gov (United States)

    Lehmann, I.; Scholz, R.-D.

    1998-02-01

    We present new tidal radii for seven Galactic globular clusters using the method of automated star counts on Schmidt plates of the Tautenburg, Palomar and UK telescopes. The plates were fully scanned with the APM system in Cambridge (UK). Special account was given to a reliable background subtraction and the correction of crowding effects in the central cluster region. For the latter we used a new kind of crowding correction based on a statistical approach to the distribution of stellar images and the luminosity function of the cluster stars in the uncrowded area. The star counts were correlated with surface brightness profiles of different authors to obtain complete projected density profiles of the globular clusters. Fitting an empirical density law (King 1962AJ.....67..471K) we derived the following structural parameters: tidal radius rt, core radius rc and concentration parameter c. In the cases of NGC 5466, M 5, M 12, M 13 and M 15 we found an indication for a tidal tail around these objects (cf. Grillmair et al., 1995AJ....109.2553G). (1 data file).

  4. Ice-Tethered Profiler observations: Vertical profiles of temperature, salinity, oxygen, and ocean velocity from an Ice-Tethered Profiler buoy system

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This collection contains repeated vertical profiles of ocean temperature and salinity versus pressure, as well as oxygen and velocity for some instruments. Data were...

  5. Ramadan fasting ameliorates arterial pulse pressure and lipid profile, and alleviates oxidative stress in hypertensive patients.

    Science.gov (United States)

    Al-Shafei, Ahmad I M

    2014-06-01

    Effects of Ramadan fasting on health are important. Its effects on arterial pulse pressure (PP), lipid profile and oxidative stress were characterized in hypertensives. PP, indices of lipid profile and oxidative stress were measured pre-, during and post-fasting in equal (40 each), sex- and age-matched groups (age 55 ± 5 years) of hypertensives (HT) and controls (C). Fasting reduced PP significantly by 17.2% and insignificantly by 9.3% in the HT and C groups, respectively. Total cholesterol (TC) was lowered insignificantly by 11.7% and 4.7% in the HT and C patients, respectively. Triglycerides (TG) and malondialdehyde (MDA) were significantly lowered by: TG: 24.5% and 22.8%; MDA: 45.6% and 54.3%; while glutathione (GSH) elevated by 56.8% and 52.6% in the HT and C groups, respectively. High-density lipoproteins (HDL) were raised significantly by 33.3% and insignificantly by 6.7%, whereas low-density lipoproteins (LDL) decreased significantly by 17.7% and insignificantly by 4.0% in the HT and C groups, respectively. At 6 weeks post-fasting, MDA remained significantly lower than the pre-fasting level by 24.3% and 25.7%, and GSH higher by 30.2% and 26.3% in the HT and C groups, respectively, while PP and TC returned to pre-fasting values in both groups. The post-fasting, HDL was significantly higher by 20.3% and LDL lower by 12.0% than the fasting levels in the HT patients. Fasting improves PP and lipids profile and ameliorates oxidative stress in hypertensives.

  6. ON THE HEATING EFFICIENCY DERIVED FROM OBSERVATIONS OF YOUNG SUPER STAR CLUSTERS IN M82

    International Nuclear Information System (INIS)

    Silich, Sergiy; Tenorio-Tagle, Guillermo; Torres-Campos, Ana; Munoz-Tunon, Casiana; Monreal-Ibero, Ana; Melo, Veronica

    2009-01-01

    Here, we discuss the mechanical feedback that massive stellar clusters provide to the interstellar medium of their host galaxy. We apply an analytic theory developed in a previous study for M82-A1 to a sample of 10 clusters located in the central zone of the starburst galaxy M82, all surrounded by compact and dense H II regions. We claim that the only way that such H II regions can survive around the selected clusters, is if they are embedded into a high-pressure ISM and if the majority of their mechanical energy is lost within the star cluster volume via strong radiative cooling. The latter implies that these clusters have a low heating efficiency, η, and evolve in the bimodal hydrodynamic regime. In this regime, the shock-heated plasma in the central zones of a cluster becomes thermally unstable, loses its pressure and is accumulated there, whereas the matter injected by supernovae and stellar winds outside this volume forms a high-velocity outflow-the star cluster wind. We calculated the heating efficiency for each of the selected clusters and found that in all cases it does not exceed 10%. Such low heating efficiency values imply a low mechanical energy output and the impact that the selected clusters provide to the ISM of M82 is thus much smaller than what one would expect using stellar cluster synthetic models.

  7. GALAXY INFALL BY INTERACTING WITH ITS ENVIRONMENT: A COMPREHENSIVE STUDY OF 340 GALAXY CLUSTERS

    Energy Technology Data Exchange (ETDEWEB)

    Gu, Liyi [SRON Netherlands Institute for Space Research, Sorbonnelaan 2, 3584 CA Utrecht (Netherlands); Wen, Zhonglue [National Astronomical Observatories, Chinese Academy of Sciences, 20A Datun Road, Chaoyang District, Beijing 100012 (China); Gandhi, Poshak [School of Physics and Astronomy, University of Southampton, Highfield, Southampton SO17 1BJ (United Kingdom); Inada, Naohisa [Department of Physics, Nara National College of Technology, Yamatokohriyama, Nara 639-1080 (Japan); Kawaharada, Madoka [Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, 3-1-1 Yoshinodai, Chuo-ku, Sagamihara, Kanagawa 229-8510 (Japan); Kodama, Tadayuki [National Astronomical Observatory of Japan, Mitaka, Tokyo 181-8588 (Japan); Konami, Saori [Department of Physics, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0397 (Japan); Nakazawa, Kazuhiro; Makishima, Kazuo [Department of Physics, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Xu, Haiguang [Department of Physics and Astronomy, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang, Shanghai 200240 (China)

    2016-07-20

    To study systematically the evolution of the angular extents of the galaxy, intracluster medium (ICM), and dark matter components in galaxy clusters, we compiled the optical and X-ray properties of a sample of 340 clusters with redshifts <0.5, based on all the available data from the Sloan Digital Sky Survey and Chandra / XMM-Newton . For each cluster, the member galaxies were determined primarily with photometric redshift measurements. The radial ICM mass distribution, as well as the total gravitational mass distribution, was derived from a spatially resolved spectral analysis of the X-ray data. When normalizing the radial profile of galaxy number to that of the ICM mass, the relative curve was found to depend significantly on the cluster redshift; it drops more steeply toward the outside in lower-redshift subsamples. The same evolution is found in the galaxy-to-total mass profile, while the ICM-to-total mass profile varies in an opposite way. The behavior of the galaxy-to-ICM distribution does not depend on the cluster mass, suggesting that the detected redshift dependence is not due to mass-related effects, such as sample selection bias. Also, it cannot be ascribed to various redshift-dependent systematic errors. We interpret that the galaxies, the ICM, and the dark matter components had similar angular distributions when a cluster was formed, while the galaxies traveling in the interior of the cluster have continuously fallen toward the center relative to the other components, and the ICM has slightly expanded relative to the dark matter although it suffers strong radiative loss. This cosmological galaxy infall, accompanied by an ICM expansion, can be explained by considering that the galaxies interact strongly with the ICM while they are moving through it. The interaction is considered to create a large energy flow of 10{sup 4445} erg s{sup 1} per cluster from the member galaxies to their environment, which is expected to continue over cosmological timescales.

  8. The effectiveness of a life style modification and peer support home blood pressure monitoring in control of hypertension: protocol for a cluster randomized controlled trial.

    Science.gov (United States)

    Su, Tin Tin; Majid, Hazreen Abdul; Nahar, Azmi Mohamed; Azizan, Nurul Ain; Hairi, Farizah Mohd; Thangiah, Nithiah; Dahlui, Maznah; Bulgiba, Awang; Murray, Liam J

    2014-01-01

    Death rates due to hypertension in low and middle income countries are higher compared to high income countries. The present study is designed to combine life style modification and home blood pressure monitoring for control of hypertension in the context of low and middle income countries. The study is a two armed, parallel group, un-blinded, cluster randomized controlled trial undertaken within lower income areas in Kuala Lumpur. Two housing complexes will be assigned to the intervention group and the other two housing complexes will be allocated in the control group. Based on power analysis, 320 participants will be recruited. The participants in the intervention group (n = 160) will undergo three main components in the intervention which are the peer support for home blood pressure monitoring, face to face health coaching on healthy diet and demonstration and training for indoor home based exercise activities while the control group will receive a pamphlet containing information on hypertension. The primary outcomes are systolic and diastolic blood pressure. Secondary outcome measures include practice of self-blood pressure monitoring, dietary intake, level of physical activity and physical fitness. The present study will evaluate the effect of lifestyle modification and peer support home blood pressure monitoring on blood pressure control, during a 6 month intervention period. Moreover, the study aims to assess whether these effects can be sustainable more than six months after the intervention has ended.

  9. Observations of different core water cluster ions Y-(H2O)n (Y = O2, HOx, NOx, COx) and magic number in atmospheric pressure negative corona discharge mass spectrometry.

    Science.gov (United States)

    Sekimoto, Kanako; Takayama, Mitsuo

    2011-01-01

    Reliable mass spectrometry data from large water clusters Y(-)(H(2)O)(n) with various negative core ions Y(-) such as O(2)(-), HO(-), HO(2)(-), NO(2)(-), NO(3)(-), NO(3)(-)(HNO(3))(2), CO(3)(-) and HCO(4)(-) have been obtained using atmospheric pressure negative corona discharge mass spectrometry. All the core Y(-) ions observed were ionic species that play a central role in tropospheric ion chemistry. These mass spectra exhibited discontinuities in ion peak intensity at certain size clusters Y(-)(H(2)O)(m) indicating specific thermochemical stability. Thus, Y(-)(H(2)O)(m) may correspond to the magic number or first hydrated shell in the cluster series Y(-)(H(2)O)(n). The high intensity discontinuity at HO(-)(H(2)O)(3) observed was the first mass spectrometric evidence for the specific stability of HO(-)(H(2)O)(3) as the first hydrated shell which Eigen postulated in 1964. The negative ion water clusters Y(-)(H(2)O)(n) observed in the mass spectra are most likely to be formed via core ion formation in the ambient discharge area (760 torr) and the growth of water clusters by adiabatic expansion in the vacuum region of the mass spectrometers (≈1 torr). The detailed mechanism of the formation of the different core water cluster ions Y(-)(H(2)O)(n) is described. Copyright © 2010 John Wiley & Sons, Ltd.

  10. Targeted Serum Metabolite Profiling Identifies Metabolic Signatures in Patients with Alzheimer's Disease, Normal Pressure Hydrocephalus and Brain Tumor

    DEFF Research Database (Denmark)

    Orešič, Matej; Anderson, Gabriella; Mattila, Ismo

    2018-01-01

    , NPH and BT samples. In the BT group, the fatty acids were increased as compared to HC and NPH groups, while the ketone body 3-hydroxybutyrate was increased as compared to AD. Glutamic acid was increased in AD as compared to the HC group. In the AD group, 3-hydroxybutyrate tended to be decreased......Progression to AD is preceded by elevated levels of 2,4-dihydroxybutanoic acid (2,4-DHB), implicating hypoxia in early pathogenesis. Since hypoxia may play a role in multiple CNS disorders, we investigated serum metabolite profiles across three disorders, AD, Normal Pressure Hydrocephalus (NPH...

  11. Magnetic diagnostics: general principles and the problem of reconstruction of plasma current and pressure profiles in toroidal systems

    Energy Technology Data Exchange (ETDEWEB)

    Pustovitov, V.D.

    2000-04-01

    The restrictions of the magnetic diagnostics are discussed. Being related to the integral nature of the measurable quantities, they follow from the fundamental laws of electromagnetism. A series of particular examples demonstrating the strength of these restrictions is given and analyzed. A general rule is emphasized that the information obtained from external magnetic measurements is obviously insufficient for the reliable evaluation of plasma current and pressure profiles in tokamaks or in stellarators. The underlying reason is that outside the plasma the own field of the equilibrium plasma currents is determined by the boundary conditions on the plasma surface only. (author)

  12. Identification and analysis of evolutionary selection pressures acting at the molecular level in five forkhead subfamilies

    Directory of Open Access Journals (Sweden)

    Rannala Bruce

    2008-09-01

    Full Text Available Abstract Background Members of the forkhead gene family act as transcription regulators in biological processes including development and metabolism. The evolution of forkhead genes has not been widely examined and selection pressures at the molecular level influencing subfamily evolution and differentiation have not been explored. Here, in silico methods were used to examine selection pressures acting on the coding sequence of five multi-species FOX protein subfamily clusters; FoxA, FoxD, FoxI, FoxO and FoxP. Results Application of site models, which estimate overall selection pressures on individual codons throughout the phylogeny, showed that the amino acid changes observed were either neutral or under negative selection. Branch-site models, which allow estimated selection pressures along specified lineages to vary as compared to the remaining phylogeny, identified positive selection along branches leading to the FoxA3 and Protostomia clades in the FoxA cluster and the branch leading to the FoxO3 clade in the FoxO cluster. Residues that may differentiate paralogs were identified in the FoxA and FoxO clusters and residues that differentiate orthologs were identified in the FoxA cluster. Neutral amino acid changes were identified in the forkhead domain of the FoxA, FoxD and FoxP clusters while positive selection was identified in the forkhead domain of the Protostomia lineage of the FoxA cluster. A series of residues under strong negative selection adjacent to the N- and C-termini of the forkhead domain were identified in all clusters analyzed suggesting a new method for refinement of domain boundaries. Extrapolation of domains among cluster members in conjunction with selection pressure information allowed prediction of residue function in the FoxA, FoxO and FoxP clusters and exclusion of known domain function in residues of the FoxA and FoxI clusters. Conclusion Consideration of selection pressures observed in conjunction with known

  13. Profile control studies for JET optimised shear regime

    Energy Technology Data Exchange (ETDEWEB)

    Litaudon, X.; Becoulet, A.; Eriksson, L.G.; Fuchs, V.; Huysmans, G.; How, J.; Moreau, D.; Rochard, F.; Tresset, G.; Zwingmann, W. [Association Euratom-CEA, CEA/Cadarache, Dept. de Recherches sur la Fusion Controlee, DRFC, 13 - Saint-Paul-lez-Durance (France); Bayetti, P.; Joffrin, E.; Maget, P.; Mayorat, M.L.; Mazon, D.; Sarazin, Y. [JET Abingdon, Oxfordshire (United Kingdom); Voitsekhovitch, I. [Universite de Provence, LPIIM, Aix-Marseille 1, 13 (France)

    2000-03-01

    This report summarises the profile control studies, i.e. preparation and analysis of JET Optimised Shear plasmas, carried out during the year 1999 within the framework of the Task-Agreement (RF/CEA/02) between JET and the Association Euratom-CEA/Cadarache. We report on our participation in the preparation of the JET Optimised Shear experiments together with their comprehensive analyses and the modelling. Emphasis is put on the various aspects of pressure profile control (core and edge pressure) together with detailed studies of current profile control by non-inductive means, in the prospects of achieving steady, high performance, Optimised Shear plasmas. (authors)

  14. HUBBLE SPACE TELESCOPE PHOTOMETRY OF GLOBULAR CLUSTERS IN M81

    International Nuclear Information System (INIS)

    Nantais, Julie B.; Huchra, John P.; Zezas, Andreas; Gazeas, Kosmas; Strader, Jay

    2011-01-01

    We perform aperture photometry and profile fitting on 419 globular cluster (GC) candidates with m V ≤ 23 mag identified in Hubble Space Telescope/Advanced Camera for Surveys BVI imaging, and estimate the effective radii of the clusters. We identify 85 previously known spectroscopically confirmed clusters, and newly identify 136 objects as good cluster candidates within the 3σ color and size ranges defined by the spectroscopically confirmed clusters, yielding a total of 221 probable GCs. The luminosity function peak for the 221 probable GCs with estimated total dereddening applied is V ∼ (20.26 ± 0.13) mag, corresponding to a distance of ∼3.7 ± 0.3 Mpc. The blue and red GC candidates, and the metal-rich and metal-poor spectroscopically confirmed clusters, respectively, are similar in half-light radius. Red confirmed clusters are about 6% larger in median half-light radius than blue confirmed clusters, and red and blue good GC candidates are nearly identical in half-light radius. The total population of confirmed and 'good' candidates shows an increase in half-light radius as a function of galactocentric distance.

  15. The impact of hydraulic flow unit & reservoir quality index on pressure profile and productivity index in multi-segments reservoirs

    Directory of Open Access Journals (Sweden)

    Salam Al-Rbeawi

    2017-12-01

    Full Text Available The objective of this paper is studying the impact of the hydraulic flow unit and reservoir quality index (RQI on pressure profile and productivity index of horizontal wells acting in finite reservoirs. Several mathematical models have been developed to investigate this impact. These models have been built based on the pressure distribution in porous media, depleted by a horizontal well, consist of multi hydraulic flow units and different reservoir quality index. The porous media are assumed to be finite rectangular reservoirs having different configurations and the wellbores may have different lengths. Several analytical models describing flow regimes have been derived wherein hydraulic flow units and reservoir quality index have been included in addition to rock and fluid properties. The impact of these two parameters on reservoir performance has also been studied using steady state productivity index.It has been found that both pressure responses and flow regimes are highly affected by the existence of multiple hydraulic flow units in the porous media and the change in reservoir quality index for these units. Positive change in the RQI could lead to positive change in both pressure drop required for reservoir fluids to move towards the wellbore and hence the productivity index.

  16. Modified Gravity and its test on galaxy clusters

    Science.gov (United States)

    Nieuwenhuizen, Theodorus M.; Morandi, Andrea; Limousin, Marceau

    2018-05-01

    The MOdified Gravity (MOG) theory of J. Moffat assumes a massive vector particle which causes a repulsive contribution to the tensor gravitation. For the galaxy cluster A1689 new data for the X-ray gas and the strong lensing properties are presented. Fits to MOG are possible by adjusting the galaxy density profile. However, this appears to work as an effective dark matter component, posing a serious problem for MOG. New gas and strong lensing data for the cluster A1835 support these conclusions and point at a tendency of the gas alone to overestimate the lensing effects in MOG theory.

  17. Implicit Priors in Galaxy Cluster Mass and Scaling Relation Determinations

    Science.gov (United States)

    Mantz, A.; Allen, S. W.

    2011-01-01

    Deriving the total masses of galaxy clusters from observations of the intracluster medium (ICM) generally requires some prior information, in addition to the assumptions of hydrostatic equilibrium and spherical symmetry. Often, this information takes the form of particular parametrized functions used to describe the cluster gas density and temperature profiles. In this paper, we investigate the implicit priors on hydrostatic masses that result from this fully parametric approach, and the implications of such priors for scaling relations formed from those masses. We show that the application of such fully parametric models of the ICM naturally imposes a prior on the slopes of the derived scaling relations, favoring the self-similar model, and argue that this prior may be influential in practice. In contrast, this bias does not exist for techniques which adopt an explicit prior on the form of the mass profile but describe the ICM non-parametrically. Constraints on the slope of the cluster mass-temperature relation in the literature show a separation based the approach employed, with the results from fully parametric ICM modeling clustering nearer the self-similar value. Given that a primary goal of scaling relation analyses is to test the self-similar model, the application of methods subject to strong, implicit priors should be avoided. Alternative methods and best practices are discussed.

  18. A comprehensive study of the young open star cluster NGC 6611 based on deep VRI CCD images and 2MASS data

    Directory of Open Access Journals (Sweden)

    I.M. Selim

    2016-06-01

    Full Text Available In the present study, we have used Deep CCD images of the extremely young open star cluster NGC 6611, up to a limiting magnitude of V ∼ 22.86 mag in V, R and I passbands. The resulting color-magnitude V; (V–I diagram as well as their radial density profiles has been determined. Using 2MASS data, we confirmed the consistency between the 2MASS photometry, by fitting isochrones, the extinction E(V–I = 0.530 ± 0.04 mag, E(J–H = 0.31 ± 0.02, from the color magnitude diagram the cluster distance =2.2 ± 0.21 kpc and age = 3.6 Myr, based on the fitting of theoretical stellar isochrones of solar metallicity Z = 0.019. The distance modulus of the cluster is estimated at 12.3. The radial stellar density profiles and the cluster center have been determined by two methods. The core and cluster radii are determined from the radial stellar density profiles. Only about 40% of the cluster members are present in the core region. The cluster luminosity function has been calculated. The mass function slope of the entire cluster is ∼−0.67 ± 0.12. The effects of mass segregation, most probably due to dynamical evolution, have been observed in the cluster.

  19. A spectroscopic census in young stellar regions: the σ Orionis cluster

    Energy Technology Data Exchange (ETDEWEB)

    Hernández, Jesús; Perez, Alice; Hernan, Ramírez [Centro de Investigaciones de Astronomía, Apdo. Postal 264, Mérida 5101-A (Venezuela, Bolivarian Republic of); Calvet, Nuria; Hartmann, Lee [Department of Astronomy, University of Michigan, 500 Church Street, Ann Arbor, MI 48109 (United States); Briceño, Cesar [Cerro Tololo Interamerican Observatory, Casilla 603, La Serena (Chile); Olguin, Lorenzo [Depto. de Investigación en Física, Universidad de Sonora, Sonora (Mexico); Contreras, Maria E. [Instituto de Astronomía, Universidad Nacional Autónoma de México, Ensenada, BC (Mexico); Allen, Lori [National Optical Astronomy Observatory, 950 North Cherry Avenue, Tucson, AZ 85719 (United States); Espaillat, Catherine, E-mail: hernandj@cida.ve [Department of Astronomy, Boston University, 725 Commonwealth Avenue, Boston, MA 02215 (United States)

    2014-10-10

    We present a spectroscopic survey of the stellar population of the σ Orionis cluster. We have obtained spectral types for 340 stars. Spectroscopic data for spectral typing come from several spectrographs with similar spectroscopic coverage and resolution. More than half of the stars in our sample are members confirmed by the presence of lithium in absorption, strong Hα in emission or weak gravity-sensitive features. In addition, we have obtained high-resolution (R ∼ 34,000) spectra in the Hα region for 169 stars in the region. Radial velocities were calculated from this data set. The radial velocity distribution for members of the cluster is in agreement with previous work. Analysis of the profile of the Hα line and infrared observations reveals two binary systems or fast rotators that mimic the Hα width expected in stars with accretion disks. On the other hand, there are stars with optically thick disks and narrow Hα profiles not expected in stars with accretion disks. This contribution constitutes the largest homogeneous spectroscopic data set of the σ Orionis cluster to date.

  20. On the coherent rotation of diffuse matter in numerical simulations of clusters of galaxies

    Science.gov (United States)

    Baldi, Anna Silvia; De Petris, Marco; Sembolini, Federico; Yepes, Gustavo; Lamagna, Luca; Rasia, Elena

    2017-03-01

    We present a study on the coherent rotation of the intracluster medium and dark matter components of simulated galaxy clusters extracted from a volume-limited sample of the MUSIC project. The set is re-simulated with three different recipes for the gas physics: (I) non-radiative, (II) radiative without active galactic nuclei (AGN) feedback and (III) radiative with AGN feedback. Our analysis is based on the 146 most massive clusters identified as relaxed, 57 per cent of the total sample. We classify these objects as rotating and non-rotating according to the gas spin parameter, a quantity that can be related to cluster observations. We find that 4 per cent of the relaxed sample is rotating according to our criterion. By looking at the radial profiles of their specific angular momentum vector, we find that the solid body model is not a suitable description of rotational motions. The radial profiles of the velocity of the dark matter show a prevalence of the random velocity dispersion. Instead, the intracluster medium profiles are characterized by a comparable contribution from the tangential velocity and the dispersion. In general, the dark matter component dominates the dynamics of the clusters, as suggested by the correlation between its angular momentum and the gas one, and by the lack of relevant differences among the three sets of simulations.

  1. Pressure/temperature/salinity profiler measurements collected in the Sea of Japan, 2001-06 to July 2001, under the sponsorship of the Office of Naval Research (NODC Accession 0002416)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Pressure/temperature/salinty profiles collected in support of a study to investigate the shallow and deep current variability in the southwest Japan/East Sea....

  2. Cosmological constraints from Chandra observations of galaxy clusters.

    Science.gov (United States)

    Allen, Steven W

    2002-09-15

    Chandra observations of rich, relaxed galaxy clusters allow the properties of the X-ray gas and the total gravitating mass to be determined precisely. Here, we present results for a sample of the most X-ray luminous, dynamically relaxed clusters known. We show that the Chandra data and independent gravitational lensing studies provide consistent answers on the mass distributions in the clusters. The mass profiles exhibit a form in good agreement with the predictions from numerical simulations. Combining Chandra results on the X-ray gas mass fractions in the clusters with independent measurements of the Hubble constant and the mean baryonic matter density in the Universe, we obtain a tight constraint on the mean total matter density of the Universe, Omega(m), and an interesting constraint on the cosmological constant, Omega(Lambda). We also describe the 'virial relations' linking the masses, X-ray temperatures and luminosities of galaxy clusters. These relations provide a key step in linking the observed number density and spatial distribution of clusters to the predictions from cosmological models. The Chandra data confirm the presence of a systematic offset of ca. 40% between the normalization of the observed mass-temperature relation and the predictions from standard simulations. This finding leads to a significant revision of the best-fit value of sigma(8) inferred from the observed temperature and luminosity functions of clusters.

  3. A cluster analysis investigation of workaholism as a syndrome.

    Science.gov (United States)

    Aziz, Shahnaz; Zickar, Michael J

    2006-01-01

    Workaholism has been conceptualized as a syndrome although there have been few tests that explicitly consider its syndrome status. The authors analyzed a three-dimensional scale of workaholism developed by Spence and Robbins (1992) using cluster analysis. The authors identified three clusters of individuals, one of which corresponded to Spence and Robbins's profile of the workaholic (high work involvement, high drive to work, low work enjoyment). Consistent with previously conjectured relations with workaholism, individuals in the workaholic cluster were more likely to label themselves as workaholics, more likely to have acquaintances label them as workaholics, and more likely to have lower life satisfaction and higher work-life imbalance. The importance of considering workaholism as a syndrome and the implications for effective interventions are discussed. Copyright 2006 APA.

  4. Persistence drives gene clustering in bacterial genomes

    Directory of Open Access Journals (Sweden)

    Rocha Eduardo PC

    2008-01-01

    Full Text Available Abstract Background Gene clustering plays an important role in the organization of the bacterial chromosome and several mechanisms have been proposed to explain its extent. However, the controversies raised about the validity of each of these mechanisms remind us that the cause of this gene organization remains an open question. Models proposed to explain clustering did not take into account the function of the gene products nor the likely presence or absence of a given gene in a genome. However, genomes harbor two very different categories of genes: those genes present in a majority of organisms – persistent genes – and those present in very few organisms – rare genes. Results We show that two classes of genes are significantly clustered in bacterial genomes: the highly persistent and the rare genes. The clustering of rare genes is readily explained by the selfish operon theory. Yet, genes persistently present in bacterial genomes are also clustered and we try to understand why. We propose a model accounting specifically for such clustering, and show that indispensability in a genome with frequent gene deletion and insertion leads to the transient clustering of these genes. The model describes how clusters are created via the gene flux that continuously introduces new genes while deleting others. We then test if known selective processes, such as co-transcription, physical interaction or functional neighborhood, account for the stabilization of these clusters. Conclusion We show that the strong selective pressure acting on the function of persistent genes, in a permanent state of flux of genes in bacterial genomes, maintaining their size fairly constant, that drives persistent genes clustering. A further selective stabilization process might contribute to maintaining the clustering.

  5. Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer's disease.

    Science.gov (United States)

    Jackson, Harriet M; Soto, Ileana; Graham, Leah C; Carter, Gregory W; Howell, Gareth R

    2013-11-25

    Alzheimer's disease affects more than 35 million people worldwide but there is no known cure. Age is the strongest risk factor for Alzheimer's disease but it is not clear how age-related changes impact the disease. Here, we used a mouse model of Alzheimer's disease to identify age-specific changes that occur prior to and at the onset of traditional Alzheimer-related phenotypes including amyloid plaque formation. To identify these early events we used transcriptional profiling of mouse brains combined with computational approaches including singular value decomposition and hierarchical clustering. Our study identifies three key events in early stages of Alzheimer's disease. First, the most important drivers of Alzheimer's disease onset in these mice are age-specific changes. These include perturbations of the ribosome and oxidative phosphorylation pathways. Second, the earliest detectable disease-specific changes occur to genes commonly associated with the hypothalamic-adrenal-pituitary (HPA) axis. These include the down-regulation of genes relating to metabolism, depression and appetite. Finally, insulin signaling, in particular the down-regulation of the insulin receptor substrate 4 (Irs4) gene, may be an important event in the transition from age-related changes to Alzheimer's disease specific-changes. A combination of transcriptional profiling combined with computational analyses has uncovered novel features relevant to Alzheimer's disease in a widely used mouse model and offers avenues for further exploration into early stages of AD.

  6. Profiling Oman education data using data mining approach

    Science.gov (United States)

    Alawi, Sultan Juma Sultan; Shaharanee, Izwan Nizal Mohd; Jamil, Jastini Mohd

    2017-10-01

    Nowadays, with a large amount of data generated by many application services in different learning fields has led to the new challenges in education field. Education portal is an important system that leads to a better development of education field. This research paper presents an innovative data mining techniques to understand and summarizes the information of Oman's education data generated from the Ministry of Education Oman "Educational Portal". This research embarks into performing student profiling of the Oman student database. This study utilized the k-means clustering technique to determine the students' profiles. An amount of 42484-student records from Sultanate of Oman has been extracted for this study. The findings of this study show the practicality of clustering technique to investigating student's profiles. Allowing for a better understanding of student's behavior and their academic performance. Oman Education Portal contain a large amounts of user activity and interaction data. Analyses of this large data can be meaningful for educator to improve the student performance level and recognize students who needed additional attention.

  7. Innovation Cluster and Economic Development in Bucharest Ilfov Region

    Directory of Open Access Journals (Sweden)

    Ana Cristina Adumitroaei

    2013-08-01

    Full Text Available Simultaneous globalisation tendencies have created policy challenges for national and local governments. One response to these challenges has been a dramatic proliferation of development policies based on clusters of firms and industries. In EU Strategy 2020 – COM 546/6.10.2010 Initiative “An Union of Innovation”, COM 614/27.10.2010 Initiative “Industrial Policy in the Globalization Era” innovative clusters were considered the “engine” of economic development. They represent a framework for business development, collaboration between companies, universities, research institutions, suppliers, customers and competitors located in the same geographical area. Clusters of small and medium sized firms in developing economies are coming under increased pressure from competition as products mature, technology becomes widely available, and companies seek lower cost locations for production. In this paper, we consider that the cluster is an engine for economic development in our region and we need to have a regional strategy for clusters in Bucharest Ilfov Regional Development Plan for 2014-2020.

  8. Wechsler Adult Intelligence Scale-Third Edition profiles and their relationship to self-reported outcome following traumatic brain injury.

    Science.gov (United States)

    Harman-Smith, Yasmin E; Mathias, Jane L; Bowden, Stephen C; Rosenfeld, Jeffrey V; Bigler, Erin D

    2013-01-01

    Neuropsychological assessments of outcome after traumatic brain injury (TBI) are often unrelated to self-reported problems after TBI. The current study cluster-analyzed the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) subtest scores from mild, moderate, and severe TBI (n=220) and orthopedic injury control (n=95) groups, to determine whether specific cognitive profiles are related to people's perceived outcomes after TBI. A two-stage cluster analysis produced 4- and 6-cluster solutions, with the 6-cluster solution better capturing subtle variations in cognitive functioning. The 6 clusters differed in the levels and profiles of cognitive performance, self-reported recovery, and education and injury severity. The findings suggest that subtle cognitive impairments after TBI should be interpreted in conjunction with patient's self-reported problems.

  9. Effect of pressure on arsenic diffusion in germanium

    International Nuclear Information System (INIS)

    Mitha, S.; Theiss, S.D.; Aziz, M.J.; Schiferl, D.; Poker, D.B.

    1994-01-01

    We report preliminary results of a study of the activation volume for diffusion of arsenic in germanium. High-temperature high-pressure anneals were performed in a liquid argon pressure medium in a diamond anvil cell capable of reaching 5 GPa and 750 C,l which is externally heated for uniform and repeatable temperature profiles. Broadening of an ion-implanted arsenic profile was measured by Secondary Ion Mass Spectrometry. Hydrostatic pressure retards the diffusivity at 575 C, characterized by an activation volume that is +15% of the atomic volume of Ge. Implications for diffusion mechanisms are discussed

  10. Evaluating and Recommending Greek Newspapers' Websites Using Clustering

    Science.gov (United States)

    Kanellopoulos, Dimitris; Kotsiantis, Sotiris

    2012-01-01

    Purpose: The aim of this work is to evaluate Greek newspaper websites using clustering and a number of criteria obtained from the Alexa search engine. Furthermore, a recommendation approach is proposed for matching Greek online newspapers with the profiles of potential readers. The paper presents the implementation and validation of a recommender…

  11. Star cluster evolution in dark matter dominated galaxies

    NARCIS (Netherlands)

    Praagman, Anneke; Hurley, Jarrod; Power, Chris

    We investigate the influence of the external tidal field of a dark matter halo on the dynamical evolution of star clusters using direct N-body simulations, where we assume that the halo is described by a Navarro, Frenk and White mass profile which has an inner density cusp. We assess how varying the

  12. Vitamin D prenatal programming of childhood metabolomics profiles at age 3 y.

    Science.gov (United States)

    Blighe, Kevin; Chawes, Bo L; Kelly, Rachel S; Mirzakhani, Hooman; McGeachie, Michael; Litonjua, Augusto A; Weiss, Scott T; Lasky-Su, Jessica A

    2017-10-01

    Background: Vitamin D deficiency is implicated in a range of common complex diseases that may be prevented by gestational vitamin D repletion. Understanding the metabolic mechanisms related to in utero vitamin D exposure may therefore shed light on complex disease susceptibility. Objective: The goal was to analyze the programming role of in utero vitamin D exposure on children's metabolomics profiles. Design: First, unsupervised clustering was done with plasma metabolomics profiles from a case-control subset of 245 children aged 3 y with and without asthma from the Vitamin D Antenatal Asthma Reduction Trial (VDAART), in which pregnant women were randomly assigned to vitamin D supplementation or placebo. Thereafter, we analyzed the influence of maternal pre- and postsupplement vitamin D concentrations on cluster membership. Finally, we used the metabolites driving the clustering of children to identify the dominant metabolic pathways that were influential in each cluster. Results: We identified 3 clusters of children characterized by 1 ) high concentrations of fatty acids and amines and low maternal postsupplement vitamin D (mean ± SD; 27.5 ± 11.0 ng/mL), 2 ) high concentrations of amines, moderate concentrations of fatty acids, and normal maternal postsupplement vitamin D (34.0 ± 14.1 ng/mL), and 3 ) low concentrations of fatty acids, amines, and normal maternal postsupplement vitamin D (35.2 ± 15.9 ng/mL). Adjusting for sample storage time, maternal age and education, and both child asthma and vitamin D concentration at age 3 y did not modify the association between maternal postsupplement vitamin D and cluster membership ( P = 0.0014). Maternal presupplement vitamin D did not influence cluster membership, whereas the combination of pre- and postsupplement concentrations did ( P = 0.03). Conclusions: Young children can be clustered into distinct biologically meaningful groups by their metabolomics profiles. The clusters differed in concentrations of

  13. DISCOVERY OF A POSSIBLY SINGLE BLUE SUPERGIANT STAR IN THE INTRA-CLUSTER REGION OF VIRGO CLUSTER OF GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Ohyama, Youichi; Hota, Ananda [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 106, Taiwan (China)

    2013-04-20

    IC 3418 is a dwarf irregular galaxy falling into the Virgo cluster, and a 17 kpc long trail is seen behind the galaxy, which is considered to have formed due to ram pressure stripping. The trail contains compact knots and diffuse blobs of ultraviolet and blue optical emission and, thus, it is a clear site of recent star formation but in an unusual environment, surrounded by a million degree intra-cluster medium. We report on our optical spectroscopy of a compact source in the trail, SDSS J122952.66+112227.8, and show that the optical spectrum is dominated by emission from a massive blue supergiant star. If confirmed, our report would mark the farthest star with spectroscopic observation. We interpret that a massive O-type star formed in situ in the trail has evolved recently out of the main sequence into this blue supergiant phase, and now lacks any detectable spectral sign of its associated H II region. We argue that turbulence within the ram pressure striped gaseous trail may play a dominant role for the star formation within such trails.

  14. DISCOVERY OF A POSSIBLY SINGLE BLUE SUPERGIANT STAR IN THE INTRA-CLUSTER REGION OF VIRGO CLUSTER OF GALAXIES

    International Nuclear Information System (INIS)

    Ohyama, Youichi; Hota, Ananda

    2013-01-01

    IC 3418 is a dwarf irregular galaxy falling into the Virgo cluster, and a 17 kpc long trail is seen behind the galaxy, which is considered to have formed due to ram pressure stripping. The trail contains compact knots and diffuse blobs of ultraviolet and blue optical emission and, thus, it is a clear site of recent star formation but in an unusual environment, surrounded by a million degree intra-cluster medium. We report on our optical spectroscopy of a compact source in the trail, SDSS J122952.66+112227.8, and show that the optical spectrum is dominated by emission from a massive blue supergiant star. If confirmed, our report would mark the farthest star with spectroscopic observation. We interpret that a massive O-type star formed in situ in the trail has evolved recently out of the main sequence into this blue supergiant phase, and now lacks any detectable spectral sign of its associated H II region. We argue that turbulence within the ram pressure striped gaseous trail may play a dominant role for the star formation within such trails.

  15. IGSA: Individual Gene Sets Analysis, including Enrichment and Clustering.

    Science.gov (United States)

    Wu, Lingxiang; Chen, Xiujie; Zhang, Denan; Zhang, Wubing; Liu, Lei; Ma, Hongzhe; Yang, Jingbo; Xie, Hongbo; Liu, Bo; Jin, Qing

    2016-01-01

    Analysis of gene sets has been widely applied in various high-throughput biological studies. One weakness in the traditional methods is that they neglect the heterogeneity of genes expressions in samples which may lead to the omission of some specific and important gene sets. It is also difficult for them to reflect the severities of disease and provide expression profiles of gene sets for individuals. We developed an application software called IGSA that leverages a powerful analytical capacity in gene sets enrichment and samples clustering. IGSA calculates gene sets expression scores for each sample and takes an accumulating clustering strategy to let the samples gather into the set according to the progress of disease from mild to severe. We focus on gastric, pancreatic and ovarian cancer data sets for the performance of IGSA. We also compared the results of IGSA in KEGG pathways enrichment with David, GSEA, SPIA, ssGSEA and analyzed the results of IGSA clustering and different similarity measurement methods. Notably, IGSA is proved to be more sensitive and specific in finding significant pathways, and can indicate related changes in pathways with the severity of disease. In addition, IGSA provides with significant gene sets profile for each sample.

  16. HBK-14 and HBK-15 Do Not Influence Blood Pressure, Lipid Profile, Glucose Level, or Liver Enzymes Activity after Chronic Treatment in Rats.

    Science.gov (United States)

    Pytka, Karolina; Głuch-Lutwin, Monika; Knutelska, Joanna; Jakubczyk, Magdalena; Waszkielewicz, Anna; Kotańska, Magdalena

    2016-01-01

    Older and even new antidepressants cause adverse effects, such as orthostatic hypotension, hyper- or hypoglycemia, liver injury or lipid disorders. In our previous experiments we showed significant antidepressant- and anxiolytic-like activities of dual 5-HT1A and 5-HT7 antagonists with α1-adrenolitic properties i.e. 1-[(2,6-dimethylphenoxy)ethoxyethyl]-4-(2-methoxyphenyl)piperazine hydrochloride (HBK-14) and 1-[(2-chloro-6-methylphenoxy)ethoxyethyl]-4-(2-methoxyphenyl)piperazine hydrochloride (HBK-15). Here, we evaluated the influence of chronic administration of HBK-14 and HBK-15 on blood pressure (non-invasive blood pressure measurement system for rodents), lipid profile (total cholesterol, low density lipoproteins-LDL, high density lipoproteins-HDL, triglycerides), glucose level, and liver enzymes activity (aspartate aminotransferase, alanine aminotransferase, γ-glutamyl transferase). We determined potential antihistaminic (isolated guinea pig ileum) and antioxidant properties (ferric reducing ability of plasma-FRAP, non-protein thiols-NPSH, stable free radical diphenylpicrylhydrazyl-DPPH) cytotoxicity. Our experiments revealed that HBK-14 and HBK-15 did not influence blood pressure, lipid profile, glucose level or liver enzymes activity in rats after 2-week treatment. We also showed that none of the compounds possessed antioxidant or cytotoxic properties at antidepressant- and anxiolytic-like doses. HBK-14 and HBK-15 very weakly blocked H1 receptors in guinea pig ileum. Positive results of our preliminary experiments on the safety of HBK-14 and HBK-15 encourage further studies concerning their effectiveness in the treatment of depression and/or anxiety disorders.

  17. HBK-14 and HBK-15 Do Not Influence Blood Pressure, Lipid Profile, Glucose Level, or Liver Enzymes Activity after Chronic Treatment in Rats.

    Directory of Open Access Journals (Sweden)

    Karolina Pytka

    Full Text Available Older and even new antidepressants cause adverse effects, such as orthostatic hypotension, hyper- or hypoglycemia, liver injury or lipid disorders. In our previous experiments we showed significant antidepressant- and anxiolytic-like activities of dual 5-HT1A and 5-HT7 antagonists with α1-adrenolitic properties i.e. 1-[(2,6-dimethylphenoxyethoxyethyl]-4-(2-methoxyphenylpiperazine hydrochloride (HBK-14 and 1-[(2-chloro-6-methylphenoxyethoxyethyl]-4-(2-methoxyphenylpiperazine hydrochloride (HBK-15. Here, we evaluated the influence of chronic administration of HBK-14 and HBK-15 on blood pressure (non-invasive blood pressure measurement system for rodents, lipid profile (total cholesterol, low density lipoproteins-LDL, high density lipoproteins-HDL, triglycerides, glucose level, and liver enzymes activity (aspartate aminotransferase, alanine aminotransferase, γ-glutamyl transferase. We determined potential antihistaminic (isolated guinea pig ileum and antioxidant properties (ferric reducing ability of plasma-FRAP, non-protein thiols-NPSH, stable free radical diphenylpicrylhydrazyl-DPPH cytotoxicity. Our experiments revealed that HBK-14 and HBK-15 did not influence blood pressure, lipid profile, glucose level or liver enzymes activity in rats after 2-week treatment. We also showed that none of the compounds possessed antioxidant or cytotoxic properties at antidepressant- and anxiolytic-like doses. HBK-14 and HBK-15 very weakly blocked H1 receptors in guinea pig ileum. Positive results of our preliminary experiments on the safety of HBK-14 and HBK-15 encourage further studies concerning their effectiveness in the treatment of depression and/or anxiety disorders.

  18. Binary model for the coma cluster of galaxies

    International Nuclear Information System (INIS)

    Valtonen, M.J.; Byrd, G.G.

    1979-01-01

    We study the dynamics of galaxies in the Coma cluster and find that the cluster is probably dominated by a central binary of galaxies NGC 4874--NGC4889. We estimate their total mass to be about 3 x 10 14 M/sub sun/ by two independent methods (assuming in Hubble constant of 100 km s -1 Mpc -1 ). This binary is efficient in dynamically ejecting smaller galaxies, some of of which are seen in projection against the inner 3 0 radius of the cluster and which, if erroneously considered as bound members, cause a serious overestimate of the mass of the entire cluster. Taking account of the ejected galaxies, we estimate the total cluster mass to be 4--9 x 10 14 M/sub sun/, with a corresponding mass-to-light ratio for a typical galaxy in the range of 20--120 solar units. The origin of the secondary maximum observed in the radial surface density profile is studied. We consider it to be a remnant of a shell of galaxies which formed around the central binary. This shell expanded, then collapsed into the binary, and is now reexpanding. This is supported by the coincidence of the minimum in the cluster eccentricity and radical velocity dispersion at the same radial distance as the secondary maximum. Numerical simulations of a cluster model with a massive central binary and a spherical shell of test particles are performed, and they reproduce the observed shape, galaxy density, and radial velocity distributions in the Coma cluster fairly well. Consequences of extending the model to other clusters are discussed

  19. Vacancy clustering and acceptor activation in nitrogen-implanted ZnO

    Science.gov (United States)

    Børseth, Thomas Moe; Tuomisto, Filip; Christensen, Jens S.; Monakhov, Edouard V.; Svensson, Bengt G.; Kuznetsov, Andrej Yu.

    2008-01-01

    The role of vacancy clustering and acceptor activation on resistivity evolution in N ion-implanted n -type hydrothermally grown bulk ZnO has been investigated by positron annihilation spectroscopy, resistivity measurements, and chemical profiling. Room temperature 220keV N implantation using doses in the low 1015cm-2 range induces small and big vacancy clusters containing at least 2 and 3-4 Zn vacancies, respectively. The small clusters are present already in as-implanted samples and remain stable up to 1000°C with no significant effect on the resistivity evolution. In contrast, formation of the big clusters at 600°C is associated with a significant increase in the free electron concentration attributed to gettering of amphoteric Li impurities by these clusters. Further annealing at 800°C results in a dramatic decrease in the free electron concentration correlated with activation of 1016-1017cm-3 acceptors likely to be N and/or Li related. The samples remain n type, however, and further annealing at 1000°C results in passivation of the acceptor states while the big clusters dissociate.

  20. Dark energy and key physical parameters of clusters of galaxies

    Science.gov (United States)

    Bisnovatyi-Kogan, G. S.; Chernin, A. D.

    2012-04-01

    We study physics of clusters of galaxies embedded in the cosmic dark energy background. Under the assumption that dark energy is described by the cosmological constant, we show that the dynamical effects of dark energy are strong in clusters like the Virgo cluster. Specifically, the key physical parameters of the dark mater halos in clusters are determined by dark energy: (1) the halo cut-off radius is practically, if not exactly, equal to the zero-gravity radius at which the dark matter gravity is balanced by the dark energy antigravity; (2) the halo averaged density is equal to two densities of dark energy; (3) the halo edge (cut-off) density is the dark energy density with a numerical factor of the unity order slightly depending on the halo profile. The cluster gravitational potential well in which the particles of the dark halo (as well as galaxies and intracluster plasma) move is strongly affected by dark energy: the maximum of the potential is located at the zero-gravity radius of the cluster.