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Sample records for clinical nuclear medicine

  1. Clinical nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine appears to be increasingly expanding both in its scope and its direct practical clinical usefullness. In view of the manifold possibilities offered by nuclear medicine this review has intentionally been very rapid and, if one will pardon the pun, a scunning approach to nuclear medicine applications. Only selected highlights in the expanding field of nuclear medicine were discussed. In the past 25 years nuclear medicine has emerged as an integrated medical discipline. It now plays a major role in patient management and has significantly expanded the physicians' diagnostic tools. As illustrated here, radionuclide procedures are currently applied in almost every medical speciality. In any event, the tests that comprise nuclear medicine have succeeded because they are rapid, effective, safe and insexpensive, and can be performed without discomfort for the patient. (orig.)

  2. Clinical nuclear medicine

    International Nuclear Information System (INIS)

    The importance of nuclear methods within today's medicine derives decisively from the field of diagnostics. Among the clinical treatment possibilities on the whole, therapy with unsealed radioactive sources is for the time being restricted to few diseases. The use of radioactive labeling in biology, biochemistry and, especially, pharmacology and the rest of fundamental medical research does not belong to the actual specialty of nuclear medicine. Nuclear in-vitro diagnostics, which currently account for about two thirds of all activities in nuclear medicine, are largely excluded from this survey, which is mainly restricted to nuclear diagnostics in vivo. This presentation of nuclear diagnostics in vivo is addressed above all to non-specialists who are to be made familiar with the modern methods of clinical nuclear medicine so that these investigation methods could be more effectively used in future both with qualitative and quantitative regards. (orig./MG)

  3. Clinical demands on nuclear medicine in neurology

    International Nuclear Information System (INIS)

    Nuclear medicine techniques can be used which are able to estimate various physiologic variables regionally in the brain. As a disadvantage of these modalities imaging function rather than morphology of brain tissue the coarse spatial resolution inherent to all isotope techniques when compared to CT and magnetic resonance imaging of protons must be accepted. The main demand on nuclear medicine techniques must therefore be the quantitation of physiologic and pathologic processes which are necessary for the understanding of pathophysiology of lesions visualized by modalities imaging morphology. (orig./MG)

  4. NMR clinical imaging and spectroscopy: Its impact on nuclear medicine

    International Nuclear Information System (INIS)

    This is a collection of four papers describing aspects of past and future use of nuclear magnetic resonance as a clinical diagnostic tool. The four papers are entitled (1) What Does NMR Offer that Nuclear Medicine Does Not? by Jerry W. Froelich, (2) Oncological Imaging: Now, Future and Impact Jerry W. Froelich, (3) Magnetic Resonance Spectroscopy/Spectroscopic Imaging and Nuclear Medicine: Past, Present and Future by H. Cecil Charles, and (4) MR Cardiology: Now, Future and Impact by Robert J. Herfkens

  5. Nuclear Medicine

    Science.gov (United States)

    ... Parents/Teachers Resource Links for Students Glossary Nuclear Medicine What is nuclear medicine? What are radioactive tracers? ... funded researchers advancing nuclear medicine? What is nuclear medicine? Nuclear medicine is a medical specialty that uses ...

  6. Nuclear medicine in clinical neurology: an update

    International Nuclear Information System (INIS)

    Isotope scanning using technetium 99m pertechnetate has fallen into disuse since the advent of x-ray computerized tomography. Regional brain blood flow studies have been pursued on a research basis. Increased regional blood flow during focal seizure activity has been demonstrated and is of use in localizing such foci. Cisternography as a predictive tool in normal pressure hydrocephalus is falling into disuse. Positron tomographic scanning is a potent research tool that can demonstrate both regional glycolysis and blood flow. Unfortunately, it is extremely expensive and complex to apply in a clinical setting. With support from the National Institutes of Health, seven extramural centers have been funded to develop positron tomographic capabilities, and they will greatly advance our knowledge of stroke pathophysiology, seizure disorders, brain tumors, and various degenerative diseases. Nuclear magnetic resonance imaging is a potentially valuable tool since it creates tomographic images representing the distribution of brain water. No tissue ionization is produced, and images comparable to second-generation computerized tomographic scans are already being produced in humans

  7. An internet-based teaching file on clinical nuclear medicine

    International Nuclear Information System (INIS)

    Objective: The goal of this project was to develop an internet-based interactive digital teaching file on nuclide imaging in clinical nuclear medicine, with the capability of access to internet. Methods: On the basis of academic teaching contents in nuclear medicine textbook for undergraduates who major in nuclear medicine, Frontpage 2000, HTML language, and JavaScript language in some parts of the contents, were utilized in the internet-based teaching file developed in this study. Results: A practical and comprehensive teaching file was accomplished and may get access with acceptable speed to internet. Besides basic teaching contents of nuclide imagings, a large number of typical and rare clinical cases, questionnaire with answers and update data in the field of nuclear medicine were included in the file. Conclusion: This teaching file meets its goal of providing an easy-to-use and internet-based digital teaching file, characteristically with the contents instant and enriched, and with the modes diversified and colorful

  8. Radioprotection in nuclear medicine department of 'Porto Alegre Clinical Hospital'

    International Nuclear Information System (INIS)

    The use of ionizing radiation in medicine allows great benefits. Nuclear Medicine uses ionizing radiation for medical diagnostic, such as: tumor, cancer, and dysfunctions location. However the use of ionizing radiation must be controlled in order to avoid likely biological effects in human beings. In order to extremely minimize that these effects appear, the Medical Physics Department of the Porto Alegre Clinical Hospital has implemented some procedures to assure that handling and use of radioactive material are in a safe way. This preoccupation is considered in all the places of nuclear medicine sector since the moment when the radioactive material is brought into including its manipulation and retirement, the exam process being accompanied. (authors). 4 refs

  9. Clinical need for nuclear medicine in paediatrics

    International Nuclear Information System (INIS)

    Full text: Bone scans. Indications for bone scans Include Infection, avascular necrosis, trauma, back ache and malignancy (primary / secondary). High quality scans are essential, this requires minimal movement of the child, a high resolution collimator and the chid lying as close as possible to the camera if not on top of the collimator. Adequate images of the hips require pin hole images. Gut. Indications include bleeding usually rectal and painless, gastro-oesophageal reflux, gastric emptying, inflammatory bowel disease either suspected or known as well as jaundice in the infant. For painless bleeding Tc 99m 04 is used usually preceded by an H 2 antagonist the day before the scan and the morning of the scan. Dynamic images are acquired for 30 - 45 minutes in the anterior position. In suspected inflammatory bowel disease, Tc 99m HMPAO labelled to WBC are required. Images must be acquired between 60 - 90 minutes as normal bowel activity is seen at 3 hours. In the jaundiced infant premedication with phenobarbitone for 3 -5 days before the scan will reduce the cases with neonatal hepatitis that fail to show tracer in the bowel. The presence of tracer in the bowel will exclude the diagnosis of biliary artesia but the absence of activity simply demands further investigation I surgery. Lungs. Indications include investigation of the abnormal chest radiograph, children with chronic lung disease (e.g. cystic fibrosis) and following surgical intervention especially pulmonary artery surgery. When feasible both perfusion and ventilation images in the posterior, both posterior oblique projections and anterior views should be obtained. In the young, perfusion views alone may have to suffice. The interpretation of a V/Q scan should always be done in conjunction with a chest radiograph. Brain. The major clinical indication for regional cerebral blood flow (rCBF) is in epilepsy. Tc 99m labelled to either HMPAO is ECD are used. The aim of the study is to identify a focus that is

  10. Clinical Training of Medical Physicists Specializing in Nuclear Medicine

    International Nuclear Information System (INIS)

    The application of radiation in human health, for both diagnosis and treatment of disease, is an important component of the work of the IAEA. The responsibility for the increasingly technical aspects of this work is undertaken by the medical physicist. To ensure good practice in this vital area, structured clinical training programmes are required to complement academic learning. This publication is intended to be a guide to the practical implementation of such a programme for nuclear medicine. There is a general and growing awareness that radiation medicine is increasingly dependent on well trained medical physicists who are based in a clinical setting. However an analysis of the availability of medical physicists indicates a large shortfall of qualified and capable professionals. This is particularly evident in developing countries. While strategies to increase educational opportunities are critical to such countries, the need for guidance on structured clinical training was recognized by the members of the Regional Cooperative Agreement for Research, Development and Training related to Nuclear Science and Technology (RCA) for the Asia-Pacific region. Consequently, a technical cooperation regional project (RAS6038) under the RCA programme was formulated to address this need in this region by developing suitable material and establishing its viability. Development of a clinical training guide for medical physicists specialising in nuclear medicine was started in 2009 with the appointment of a core drafting committee of regional and international experts. The publication drew on the experience of clinical training in Australia, Croatia and Sweden and was moderated by physicists working in the Asian region. The present publication follows the approach of earlier IAEA publications in the Training Course Series, specifically Nos 37 and 47, Clinical Training of Medical Physicists Specializing in Radiation Oncology and Clinical Training of Medical Physicists

  11. Nuclear Medicine.

    Science.gov (United States)

    Badawi, Ramsey D.

    2001-01-01

    Describes the use of nuclear medicine techniques in diagnosis and therapy. Describes instrumentation in diagnostic nuclear medicine and predicts future trends in nuclear medicine imaging technology. (Author/MM)

  12. Clinical nuclear medicine applications in Turkey and specific renal studies

    International Nuclear Information System (INIS)

    Nuclear cardiology, nuclear oncology, pediatric nuclear medicine and nuclear endocrinology are the main application areas of clinical nuclear medicine in Turkey. Not only imaging studies, but also therapeutic application of radiopharmaceuticals is also performed at many institutes, such as hyperthyroidism treatment with radioiodine, thyroid cancer ablation and metastases treatment with radioiodine, radio synovectomy, metastatic pain therapy, and recently radioimmunotherapy of lymphomas. Almost all radionuclides and radiopharmaceuticals are obtained commercially from European countries, except 18-FDG which is obtained from two cyclotrons in Turkey. More than 30.000 renal procedures are performed at the University hospitals in a year. Pediatric age groups is approximately % 55 of patients. 99mTc-DTPA (%44), 99mTc-DMSA (%37), 99mTc-MAG3 (%17) and 99mTc-EC (%2) are the most commonly used radiopharmaceuticals for renal imaging. More than 6.000 vials of several pharmaceuticals are used for renal cortical scintigraphy (%35), dynamic renal imaging (%34), renal scintigraphy with diuretic (%27) and captopril scintigraphy (%4). Most common indication for renal cortical scintigraphy is detection of cortical scarring (%53). In addition, using single plasma sample method or gamma-camera method renal clearance measurements with 99mTc-MAG3 99mTc-DTPA have been used at some institutions. (author)

  13. Clinical nuclear medicine applications in Turkey and specific renal studies

    International Nuclear Information System (INIS)

    Full text: Nuclear cardiology, nuclear oncology, pediatric nuclear medicine and nuclear endocrinology are the main application areas of clinical nuclear medicine in Turkey. Not only imaging studies, but also therapeutic application of radiopharmaceuticals is also performed at many institutes, such as hyperthyroidism treatment with radioiodine, thyroid cancer ablation and metastases treatment with radioiodine, radio synovectomy, metastatic pain therapy, and recently radioimmunotherapy of lymphomas. Almost all radionuclides and radiopharmaceuticals are obtained commercially from European countries, except 18-FDG which is obtained from two cyclotrons in Turkey. More than 30.000 renal procedures are performed at the University hospitals in a year. Pediatric age groups is approximately % 55 of patients. 99mTc-DTPA (%44), 99mTc-DMSA (%37), 99mTc-MAG3 (%17) and 99mTc-EC (%2) are the most commonly used radiopharmaceuticals for renal imaging. More than 6.000 vials of several pharmaceuticals are used for renal cortical scintigraphy (%35), dynamic renal imaging (%34), renal scintigraphy with diuretic (%27) and captopril scintigraphy (%4). Most common indication for renal cortical scintigraphy is detection of cortical scarring (%53). In addition, using single plasma sample method or gamma-camera method renal clearance measurements with 99mTc-MAG3 99mTc-DTPA have been used at some institutions

  14. Nuclear medicine

    International Nuclear Information System (INIS)

    Several growth areas for nuclear medicine were defined. Among them were: cardiac nuclear medicine, neuro-psychiatric nuclear medicine, and cancer diagnosis through direct tumor imaging. A powerful new tool, Positron Emission Tomography (PET) was lauded as the impetus for new developments in nuclear medicine. The political environment (funding, degree of autonomy) was discussed, as were the economic and scientific environments

  15. An atlas of clinical nuclear medicine. 2. ed.

    International Nuclear Information System (INIS)

    Although only five years have passed since the first edition of 'An Atlas of Clinical Nuclear Medicine' was published, a number of new radiopharmaceuticals have been accepted into routine clinical practice and single photon emission computed tomographic imaging (SPECT) has now become widely available. This edition of the Atlas has been fully revised to cover these recent advances, while retaining the best of the material from the previous edition. In addition, there are new chapters on tumour imaging and gastrointestinal studies. Without detracting from the comprehensiveness of the first edition, the book has been completely restructured to enhance its use as a teaching aid. Each chapter is divided into four sections: anatomy and physiology; radiopharmaceuticals; normal scans with variants and artefacts; and clinical applications. (orig.)

  16. Time characteristics of photon fields at a nuclear medicine clinic

    International Nuclear Information System (INIS)

    The radiation fields were measured at the Nuclear Medicine Clinic of the Faculty Hospital in Prague-Motol. Gamma photons from iodine 131 administered to the patients is the main contributor to the fields. The dose rates at short distances from the patients can be as high as 20 mSv/h, whereby the cumulated doses to the health care personnel can exceed the annual limits for professional exposures. It is very important that unnecessary close contact with the patients be avoided unless emergency of other urgent procedures are required. Administration of high activities to several patients sharing a room in the ward should also be taken into account when handling the patients (including food service, housekeeping, changing linen, etc.). In normal circumstances, the radiation level in corridors and at other places accessible to cancer patients within the clinic are usually below 5 μSv/h averaged for 1 min intervals. (P.A.)

  17. Patient and population exposure from clinic nuclear medicine in China

    International Nuclear Information System (INIS)

    In the work, a method of epidemiological stratified sampling was adopted. The sampling covers 200 hospitals throughout 24 provinces. The patient doses were estimated by MIRD method. The survey data were statistic analysis by a computer, and main results of the annual frequencies, patient dose and collective dose were reported. The annual frequency of clinic nuclear medicine in China was 0.62 cases per 1000 inhabitant. The highest frequency was found in thyroid uptake procedure, it is 0.26 cases per 1000 population. The patient dose per examination is changed with various radiopharmaceuticals administered mainly. In nuclear medical examination, the highest effective dose per examination was found in the procedure of thyroid scintigraphy, it is about 93.8 mGy lexam with 131I, and this is 312 times as that with 99mTc. In hyperthyroidism, the patient dose is very high, the effective dose is 2.6 Gy lexam, the thyroid dose is 86.0 Gy lexam. (5 tabs.)

  18. Impact of quality management on clinical nuclear medicine practice

    International Nuclear Information System (INIS)

    In many countries, imaging facilities are simply not available or not functioning. In other areas, a large number of images are of poor quality and are of no diagnostic use. Many are also misread and this is frequent in developing as well as in developed countries. The main reason is the lack of adequately trained medical specialists, including radiologists, nuclear medicine physicians, physicists and technologists. Inadequate training means a lack of qualified personnel and improper use of equipment and incorrect interpretation of images. Lack of appropriate technology due to limited resources, poor maintenance of existing equipment due to a lack of available parts and inadequate training are also important factors affecting the clinical usefulness of imaging tests. Recent reports of the European Commission and of the Italian Agency for Regional Health Services have documented that up to 30-50% of imaging tests are partially or totally inappropriate. Inappropriate selection of tests determines doubtful or inconclusive results which may request a further sequence of inappropriate tests. Wrong tests may produce wrong results and wrong diagnoses and, therefore, wrong and dangerous treatments. The most frequent causes are: 1) repeating investigations that have already been done, 2) investigation when results are unlikely to affect patient management, 3) investigating too often, 4) doing the wrong investigation, 5) failing to provide appropriate clinical information and questions that the imaging investigation should answer, (6) over investigating. Clinicians, when considering the need of an imaging test, should first investigate themselves with a very simple question: what will I do after a positive or negative result? If the answer is 'nothing in both cases' that means that the request is not justified. The first step of quality control in clinical practice is the application of guidelines aimed to define useful application of imaging tests. Guidelines are

  19. Dictionary/handbook of nuclear medicine and clinical imaging

    International Nuclear Information System (INIS)

    This book covers the following topics: Fundamentals of English medical etymology, Abbreviations, acronyms, symbols, denotations, and signs commonly used or defined in the dictionary, Characteristics of the elements, Characteristics of practicable radioisotopes and of selected radionuclides commonly used in nuclear medicine, Properties and production of radionuclides, Radioactive decay, Radiopharmaceuticals, and Radiation dosimetry

  20. Portable gamma camera for clinical use in nuclear medicine

    International Nuclear Information System (INIS)

    Up today Hamamatsu R3292 is the Position Sensitive Photo Multiplier Tube (PSPMT) with the largest sensitive area (10 cm of diameter). At the same time it has the minimum size for clinical application in Nuclear Medicine. A portable gamma camera was realized, based on 5 inches PSPMT coupled to a scintillating array. The head has a light weight (15 Kg.) spatial resolution resulted better than that of Anger Camera with good linearity response, good energy resolution and FOV coincident with intrinsic one of PSPMT. To optimize gamma camera response two different scintillating arrays were tested: YAP:Ce and CsI (Tl). Their overall size cover all photochatode active area, and crystal pixel size was 2 mm x 2 mm. The detection efficiency resulted comparable to that of Anger Camera. The best result was obtained by CsI (Tl) scintillating: an intrinsic spatial resolution of 1.6 mm FWHM and a relative energy resolution of 17% FWHM. With a standard general purpose collimator a spatial resolution of about 2 mm resulted. Some preliminary results were also obtained in breast scintigraphy

  1. Nuclear medicine

    International Nuclear Information System (INIS)

    The article deals with the growth of nuclear medicine in India. Radiopharmaceuticals both in elemental form and radiolabelled compounds became commercially available in India in 1961. Objectives and educational efforts of the Radiation Medicine Centre setup in Bombay are mentioned. In vivo tests of nuclear medicine such as imaging procedures, dynamic studies, dilution studies, thyroid function studies, renal function studies, linear function studies, blood flow, and absorption studies are reported. Techniques of radioimmunoassay are also mentioned. (S.K.K.)

  2. Nuclear medicine

    International Nuclear Information System (INIS)

    The task of the Expert Committee was to review the technical development and efficacy of nuclear medicine methods and to recommend the best possible means of establishing nuclear medicine services at various levels of medical care in different countries. After reviewing the contributions which nuclear medicine can make, the various types of medical institutions and hospitals in existence, the requirements, organization and funding of nuclear medicine services, and the cost/effectiveness of nuclear medicine, a number of recommendations were made. IAEA and WHO should make information on existing methods of cost/effectiveness analysis widely available; invite governments to include a description of such analysis methods in training programmes of their health officers; assist in the acquisition of the necessary data; and encourage and eventually support actual applications of such analyses to carefully selected nuclear medicine procedures in varying medicosocial environments. They were further recommended to study possible ways of improving reliability and ease of servicing nuclear medicine equipment, and extent of possible local construction; the possibility of making available supplies of matched characterized reagents for radioimmunoassay and related techniques; and to study the advantages of establishing a network of collaborating centres on an international basis

  3. Fundamentals of nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Alazraki, N.P.; Mishkin, F.S.

    1984-01-01

    This guidebook for clinical nuclear medicine is written as a description of how nuclear medicine procedures should be used by clinicians in evaluating their patients. It is designed to assist medical students and physicians in becoming acquainted with nuclear medicine techniques for detecting and evaluating most common disorders. The material provides an introduction to, not a textbook of, nuclear medicine. Each chapter is devoted to a particular organ system or topic relevant to the risks and benefits involved in nuclear medicine studies. The emphasis is on presenting the rationales for ordering the various clinical imaging procedures performed in most nuclear medicine departments. Where appropriate, alternative imaging modalities including ultrasound, computed tomography imaging, and radiographic special procedures are discussed. Comparative data between nuclear medicine imaging and other modalities are presented to help guide the practicing clinician in the selection of the most appropriate procedure for a given problem.

  4. Handbook of nuclear medicine and molecular imaging principles and clinical applications

    CERN Document Server

    Kim, Edmund E; Tateishi, Ukihide; Baum, Richard P

    2012-01-01

    This handbook will provide updated information on nuclear medicine and molecular imaging techniques as well as its clinical applications, including radionuclide therapy, to trainees and practitioners of nuclear medicine, radiology and general medicine. Updated information on nuclear medicine and molecular imaging are vitally important and useful to both trainees and existing practitioners. Imaging techniques and agents are advancing and changing so rapidly that concise and pertinent information are absolutely necessary and helpful. It is hoped that this handbook will help readers be better equipped for the utilization of new imaging methods and treatments using radiopharmaceuticals.

  5. Nuclear medicine

    International Nuclear Information System (INIS)

    Despite an aggressive, competitive diagnostic radiology department, the University Hospital, London, Ontario has seen a decline of 11% total (in vivo and in the laboratory) in the nuclear medicine workload between 1982 and 1985. The decline of in vivo work alone was 24%. This trend has already been noted in the U.S.. Nuclear medicine is no longer 'a large volume prosperous specialty of wide diagnostic application'

  6. General Nuclear Medicine

    Science.gov (United States)

    ... Resources Professions Site Index A-Z General Nuclear Medicine Nuclear medicine imaging uses small amounts of radioactive ... of General Nuclear Medicine? What is General Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  7. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  8. Children's (Pediatric) Nuclear Medicine

    Science.gov (United States)

    ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  9. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small ... of Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical ...

  10. Nuclear Medicine

    OpenAIRE

    Belzberg, Allan S.

    1986-01-01

    Nuclear medicine utilizes radioisotopes to diagnose and in some cases treat disease. Modern instruments can image their accumulation in an organ and provide quantitative data when indicated. The strength of these procedures is in the unique physiologic information they provide, rather than the presentation of precise anatomic detail.

  11. Nuclear medicine

    International Nuclear Information System (INIS)

    The document contains two articles dealing with the radioisotope scintigraphy of myocardium and gullet and forty-one abstracts of papers presented at the seminar ''Twenty-nine Days of Nuclear Medicine'' held in Olomovc, September 29 - October 1, 1992. The contributions, all within the INIS subject scope, are input to INIS. (Z.S.)

  12. Clinical applications of factor analysis in nuclear medicine

    International Nuclear Information System (INIS)

    Factor analysis allows to break up dynamic radionuclide studies into constituent parts corresponding to the individual compartments of the distribution space of the radiopharmaceutical in the body. The compartment structure is reflected by a factor image and its dynamics is shown by factor time activity curves. The method overcomes the drawbacks of other data processing methods in dynamic scintigraphy by its objectiveness and by distinguishing the projection overlap of tissues with different dynamics. The demands on both the patient and personnel are similar to those in standard procedures yet this method extracts more information from the results of the examination. Higher diagnostic accuracy was reported especially in nuclear cardiology and nephrology. A short survey of clinical applications of factor analysis reported over the years 1982-1988 is presented. (author). 6 figs., 54 refs

  13. Practical nuclear medicine

    CERN Document Server

    Gemmell, Howard G; Sharp, Peter F

    2006-01-01

    Nuclear medicine plays a crucial role in patient care, and this book is an essential guide for all practitioners to the many techniques that inform clinical management. The first part covers the scientific basis of nuclear medicine, the rest of the book deals with clinical applications. Diagnostic imaging has an increasingly important role in patient management and, despite advances in other modalities (functional MRI and spiral CT), nuclear medicine continues to make its unique contribution by its ability to demonstrate physiological function. This book is also expanded by covering areas of d

  14. Nuclear medicine

    International Nuclear Information System (INIS)

    Except for dedicated devices for mobile nuclear cardiology for instance, the market is set on variable angulation dual heads cameras. These cameras are suited for all general applications and their cost effectiveness is optimized. Now, all major companies have such a camera in their of products. But, the big question in nuclear medicine is about the future of coincidence imaging for the monitoring of treatments in oncology. Many companies are focused on WIP assessments to find out the right crustal thickness to perform both high energy FDG procedures and low energy Tc procedures, with the same SPECT camera. The classic thickness is 3/8''. Assessments are made with 1/2'', 5/8'' or 3/4'' crystals. If FDG procedures proved to be of great interest in oncology, it may lead to the design of a dedicated SPECT camera with a 1'' crustal. Due to the short half of FDG, it may be the dawning of slip ring technology. (e.g. Varicam from Elscint). The three small heads camera market seems to be depressed. Will the new three large heads camera unveiled by Picker, reverse that trend? The last important topic in nuclear medicine is the emergence of new flat digital detectors to get rid of the old bulky ones. Digirad is the first company to manufacture a commercial product based on that technology. Bichron, Siemens and General Electric are working on that development, too. But that technology is very expensive and the market for digital detection in nuclear medicine is not as large as the market in digital detection in radiology. (author)

  15. Clinical applications of PET-CT in nuclear medicine to medical specialists

    International Nuclear Information System (INIS)

    This regional training course about Clinical Applications of PET-Tc in nuclear medicine include: imaging, pathology, scintigraphy, computed tomography, radiology, endoscopy, magnetic resonance, biopsy, and histology. It also describes pathologies and diseases of organs and bone structures such as: musculoskeletal and osseous damage, tumors, fibroids, metastasize, neoplasm, adenopathies and cancer of liver, brain, glands, kidney, neck, thorax, lungs, uterus, ovaries, craniums, hypophysis etc

  16. Veterinary nuclear medicine

    International Nuclear Information System (INIS)

    A brief review is presented of the expanding horizons of nuclear medicine, the equipment necessary for a nuclear medicine laboratory is listed, and the value of this relatively new field to the veterinary clinician is indicated. Although clinical applications to veterinary medicine have not kept pace with those of human medicine, many advances have been made, particularly in the use of in vitro techniques. Areas for expanded applications should include competitive protein binding and other in vitro procedures, particularly in connection with metabolic profile studies. Indicated also is more intensive application by the veterinarian of imaging procedures, which have been found to be of such great value to the physician. (U.S.)

  17. Verification of radioactive waste management of nuclear medicine clinics in the city of Recife

    International Nuclear Information System (INIS)

    The increasing use of ionizing radiation in various areas can not be dissociated from the concerns of safety and radiation security. In Nuclear Medicine, this concern becomes higher, because of the radionuclides used in diagnosis and therapy of radiation sources are not sealed. Their use inevitably produces radioactive waste that must be controlled through proper management, according to the normative standards established in Brazil by the National Commission of Nuclear Energy (CNEN). The management of radioactive waste seeks to lower the occupational doses besides the environmental preservation. In the work carried out by the Regional Center of Nuclear Sciences Northeast (CRCN-NE) and the Federal Office for Education, Science and Technology (OPSI), we see the systems management of radioactive waste from Nuclear Medicine in the city of Recife. The results were obtained from the preparation of a sheet of compliance and its implementation in eight clinics. (author)

  18. Monitoring of radiation dose rates around a clinical nuclear medicine site

    International Nuclear Information System (INIS)

    The monitoring of radiation dose around the nuclear medicine site is an important study issue. In this study, TLD-100H radiation dosimeters were used to measure the ambient radiation dose rates around a clinical nuclear medicine site in order to investigate the latent hot zones of radiation exposure. Results of this study showed that the radiation doses measured from all piping and storage systems were comparable to the background dose. A relatively high dose was observed at the single bend point of waste water piping of the PET/CT. Another important finding was the unexpected high dose rates observed at the non-restricted waiting area (NRWA) of SPECT. To conclude, this study provides useful information for further determination of an appropriate dose reduction strategy to achieve the ALARA principle in a clinical nuclear medicine site. - Highlights: • Observed unexpected high dose rates in the non restricted waiting area. • Provides useful Radiation Dose Rates information in nuclear medicine radioactive waste water pipeline system. • Provide TLD setup method in environmental radiation dose evaluate

  19. Nuclear medicine

    International Nuclear Information System (INIS)

    This article presents a brief history of nuclear medicine in France and describes the recent developments and equipment of the 3 techniques most used in hospital nuclear departments: 1) gamma-camera, 2) single photon emission computed tomography (SPECT), and 3) positron emission computed tomography (PECT). Concerning gamma-camera, a new design is being studied in a collaboration between the Saint-Gobain company and the LETI (a laboratory of Cea). In this innovative design the scintillator and the photomultiplier are replaced by a matrix of semi-conductor detectors based on CdZnTe crystal combined with an adequate electronic equipment. Concerning SPECT, many different techniques and equipment are used. Most improvements handle with the reduction of the survey time for the patient by using several detectors set on a ring around the patient. Concerning PECT, the developments follow 2 parallel ways: first the use of better scintillating materials for detecting 511 KeV photons (BGO: bismuth germanate, BaF2, LSO: lutetium orthosilicate, or GSO: gadolinium orthosilicate), and secondly the use of beta+ decay radionuclides that are more easily integrated in molecules similar to those present in the humane metabolism (18F through the fluorodeoxyglucose molecule). (A.C.)

  20. What Is Nuclear Medicine?

    Science.gov (United States)

    What is nuclear medicine? Nuclear medicine is a medical specialty that is used to diagnose and treat diseases in a safe and painless way. Nuclear medicine procedures permit the determination of medical information ...

  1. Clinical Training of Medical Physicists Specializing in Nuclear Medicine (Spanish Edition)

    International Nuclear Information System (INIS)

    The application of radiation in human health, for both diagnosis and treatment of disease, is an important component of the work of the IAEA. The responsibility for the increasingly technical aspects of this work is undertaken by the medical physicist. To ensure good practice in this vital area, structured clinical training programmes are required to complement academic learning. This publication is intended to be a guide to the practical implementation of such a programme for nuclear medicine. There is a general and growing awareness that radiation medicine is increasingly dependent on well trained medical physicists who are based in a clinical setting. However an analysis of the availability of medical physicists indicates a large shortfall of qualified and capable professionals. This is particularly evident in developing countries. While strategies to increase educational opportunities are critical to such countries, the need for guidance on structured clinical training was recognized by the members of the Regional Cooperative Agreement for Research, Development and Training related to Nuclear Science and Technology (RCA) for the Asia-Pacific region. Consequently, a technical cooperation regional project (RAS6038) under the RCA programme was formulated to address this need in this region by developing suitable material and establishing its viability. Development of a clinical training guide for medical physicists specialising in nuclear medicine was started in 2009 with the appointment of a core drafting committee of regional and international experts. The publication drew on the experience of clinical training in Australia, Croatia and Sweden and was moderated by physicists working in the Asian region. The present publication follows the approach of earlier IAEA publications in the Training Course Series, specifically Nos 37 and 47, Clinical Training of Medical Physicists Specializing in Radiation Oncology and Clinical Training of Medical Physicists

  2. Clinical Training of Medical Physicists Specializing in Nuclear Medicine (French Edition)

    International Nuclear Information System (INIS)

    The application of radiation in human health, for both diagnosis and treatment of disease, is an important component of the work of the IAEA. The responsibility for the increasingly technical aspects of this work is undertaken by the medical physicist. To ensure good practice in this vital area, structured clinical training programmes are required to complement academic learning. This publication is intended to be a guide to the practical implementation of such a programme for nuclear medicine. There is a general and growing awareness that radiation medicine is increasingly dependent on well trained medical physicists who are based in a clinical setting. However an analysis of the availability of medical physicists indicates a large shortfall of qualified and capable professionals. This is particularly evident in developing countries. While strategies to increase educational opportunities are critical to such countries, the need for guidance on structured clinical training was recognized by the members of the Regional Cooperative Agreement for Research, Development and Training related to Nuclear Science and Technology (RCA) for the Asia-Pacific region. Consequently, a technical cooperation regional project (RAS6038) under the RCA programme was formulated to address this need in this region by developing suitable material and establishing its viability. Development of a clinical training guide for medical physicists specialising in nuclear medicine was started in 2009 with the appointment of a core drafting committee of regional and international experts. The publication drew on the experience of clinical training in Australia, Croatia and Sweden and was moderated by physicists working in the Asian region. The present publication follows the approach of earlier IAEA publications in the Training Course Series, specifically Nos 37 and 47, Clinical Training of Medical Physicists Specializing in Radiation Oncology and Clinical Training of Medical Physicists

  3. Radiation protection in the department of nuclear medicine in the clinical center of Montenegro

    International Nuclear Information System (INIS)

    Radiation protection in the Department of nuclear medicine in the Clinical center of Montenegro - Podgorica, is presented. Particularly, environment irradiation is discussed and dose rate is calculated in dependence on source distance. A last monthly doses measurement for six employees in this Department showed doses of 50 μSv, 53 μSv, 49 μSv, 62 μSv, 111 μSv and 118 μSv

  4. Spatial map dose of nuclear medicine service of the Clinical Hospital of Botucatu, SP, Brazil

    International Nuclear Information System (INIS)

    This study was conducted to describe levels of occupational and environmental exposure of the Nuclear Medicine Service of the Clinical Hospital of Botucatu. To this end, measurements were made of the radiometric levels of points strategically defined, in all the environments, for a period of six months, sampling different days and times, during operation normal routine of the sector. The results allow to estimate the expected dose for each environment, comparing them to the dose limitation established by the National Commission of Nuclear Energy (CNEN), allowing better targeting of occupationally exposed individuals, indicating the points where the occupation should be the minimum required, enabling the reduction of risks to potential exposures. (author)

  5. Tumour angiogenesis pathways: related clinical issues and implications for nuclear medicine imaging

    International Nuclear Information System (INIS)

    Tumour angiogenesis is essential for growth, invasion and metastasis. Retrospective studies suggest that it is an independent prognostic factor that merits prospective validation. Furthermore, as tumour blood vessels show many differences from normal vessels and are not genetically unstable, they form a key area for therapy development. However, as anti-angiogenic therapy is primarily cytostatic and not cytotoxic, novel tailor-made specific end-points for treatment monitoring are required. In this regard, suitable molecular parameters for imaging tumour angiogenesis by means of nuclear medicine are being explored. Here we review current knowledge on the multiple pathways controlling tumour angiogenesis and try to assess which are the most clinically relevant for nuclear medicine imaging. Parameters that may influence the imaging potential of radiopharmaceuticals for angiogenesis imaging such as molecular weight and structure, their targeted location within the tumour and their usefulness in terms of specificity and constancy of the targeted molecular pathway are discussed. (orig.)

  6. Nuclear medicine resources manual

    International Nuclear Information System (INIS)

    Over the past decade many IAEA programmes have significantly enhanced the capabilities of numerous Member States in the field of nuclear medicine. Functional imaging using nuclear medicine procedures has become an indispensable tool for the diagnosis, treatment planning and management of patients. However, due to the heterogeneous growth and development of nuclear medicine in the IAEA's Member States, the operating standards of practice vary considerably from country to country and region to region. This publication is the result of the work of over 30 international professionals who have assisted the IAEA in the process of standardization and harmonization. This manual sets out the prerequisites for the establishment of a nuclear medicine service, including basic infrastructure, suitable premises, reliable supply of electricity, maintenance of a steady temperature, dust exclusion for gamma cameras and radiopharmacy dispensaries. It offers clear guidance on human resources and training needs for medical doctors, technologists, radiopharmaceutical scientists, physicists and specialist nurses in the practice of nuclear medicine. The manual describes the requirements for safe preparation and quality control of radiopharmaceuticals. In addition, it contains essential requirements for maintenance of facilities and instruments, for radiation hygiene and for optimization of nuclear medicine operational performance with the use of working clinical protocols. The result is a comprehensive guide at an international level that contains practical suggestions based on the experience of professionals around the globe. This publication will be of interest to nuclear medicine physicians, radiologists, medical educationalists, diagnostic centre managers, medical physicists, medical technologists, radiopharmacists, specialist nurses, clinical scientists and those engaged in quality assurance and control systems in public health in both developed and developing countries

  7. A scheme for the audit of scientific and technological standards in clinical nuclear medicine

    International Nuclear Information System (INIS)

    Aim: Audit is the process whereby the quality of a service is monitored and optimised. It forms an essential component of the quality assurance process, whether by self-assessment or by external peer review. In the UK the British Nuclear Medicine Society (BNMS) has undertaken external organisational audit of departments providing clinical nuclear medicine services. This work aimed to develop a more thorough and service specific process for the audit of scientific and technological standards in nuclear medicine. Materials and Methods: The audit process has been implemented using written audit documents to facilitate the audit procedure. A questionnaire forms part of the formal documentation for audit of the scientific and technical standards of a clinical service. Scientific and technical standards were derived from a number of sources including legal requirements, regulatory obligations, notes for guidance, peer reviewed publications and accepted good clinical practice (GCP). Results: The audit process graded the standards of an individual department according to legal or safety requirements (Grade A), good practice (Grade B) and desirable aspects of service delivery (Grade C). The standards have been allocated into eight main categories. These are: Instrumentation; Software and data protection; Electrical Safety; Mechanical Safety; Workstation Safety; The Control of Substances Hazardous to Health (COSHH); Radiation Protection; Scientific and Technical staffing levels. During the audit visit a detailed inspection of clinical and laboratory areas and department written documentation is also necessary to validate the data obtained. Conclusion: The printed scheme now provides a means for external audit or self-assessment. There should be evidence of a well-organised and safe environment for both patients and staff. Health and Safety legislation requires written local rules and these records should be available to demonstrate the standard of service provision. Other

  8. Pediatric nuclear medicine

    International Nuclear Information System (INIS)

    This symposium presented the latest techniques and approaches to the proper medical application of radionuclides in pediatrics. An expert faculty, comprised of specialists in the field of pediatric nuclear medicine, discussed the major indications as well as the advantages and potential hazards of nuclear medicine procedures compared to other diagnostic modalities. In recent years, newer radiopharmaceuticals labeled with technetium-99m and other short-lived radionuclides with relatively favorable radiation characteristics have permitted a variety of diagnostic studies that are very useful clinically and carry a substantially lower radiation burden then many comparable X-ray studies. This new battery of nuclear medicine procedures is now widely available for diagnosis and management of pediatric patients. Many recent research studies in children have yielded data concerning the effacacy of these procedures, and current recommendations will be presented by those involved in conducting such studies. Individual papers are processed separately for the Energy Data Base

  9. Pediatric nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    This symposium presented the latest techniques and approaches to the proper medical application of radionuclides in pediatrics. An expert faculty, comprised of specialists in the field of pediatric nuclear medicine, discussed the major indications as well as the advantages and potential hazards of nuclear medicine procedures compared to other diagnostic modalities. In recent years, newer radiopharmaceuticals labeled with technetium-99m and other short-lived radionuclides with relatively favorable radiation characteristics have permitted a variety of diagnostic studies that are very useful clinically and carry a substantially lower radiation burden then many comparable X-ray studies. This new battery of nuclear medicine procedures is now widely available for diagnosis and management of pediatric patients. Many recent research studies in children have yielded data concerning the effacacy of these procedures, and current recommendations will be presented by those involved in conducting such studies. Individual papers are processed separately for the Energy Data Base.

  10. National comparison of 131I measurement among nuclear medicine clinics of eight countries

    International Nuclear Information System (INIS)

    A generally applicable protocol for organizing comparisons among nuclear medicine clinics created within the IAEA project CRP E2.10.05 was tested in Brazil, Cuba, Czech Republic, India, Iran, Republic of Korea, Romania and Turkey in 2007. Comparisons of measurement of 131I were organized by local pilot laboratories with different backgrounds and levels of experience in this field. The results and experiences gained were compared and analyzed. A majority of results in each national comparison were within 10% of the reference value.

  11. International conference on clinical PET and molecular nuclear medicine (IPET 2007). Book of abstracts

    International Nuclear Information System (INIS)

    The International Atomic Energy Agency is organizing its first international conference on 'Clinical PET and Molecular Nuclear Medicine'. Medical imaging technologies have undergone explosive growth over the past two decades. Today, imaging is at a crossroad, with molecular targeted imaging agents expected to broadly expand the capabilities of conventional anatomical imaging methods. Observing molecular interactions in the living body by the radiotracer technique has become known as 'molecular nuclear medicine'. Molecular nuclear medicine techniques analyze cellular biochemistry and its relationship to disease processes expressed in tissue and organ dysfunction, for diagnostic and therapeutic purposes. People can often have similar manifestations of disease, but no two patients will be the same. Functional radionuclide imaging and positron emission tomography (PET) provide excellent opportunities to follow the pathology in individual patients and therefore provide a means for tailored clinical management. These also provide the means to assess the response to treatment in a safe and non-invasive manner. Changes at molecular and cellular levels provide vital clues for evaluating the effectiveness of chosen clinical treatment plans. This information is expected to have a major impact on understanding disease, disease detection, individualised treatment, and drug development. Recently, considerable attention has been drawn to nuclear medicine with the visualization of biochemical processes in vivo such as PET studies with 18F-FDG in many different organs and in cancerous tissues. With the arrival of PET/CT systems there is a new era of accurate mapping of disease processes. Today, 18F-FDG is the most useful PET tracer for the detection, staging, treatment planning and management of cancer. There is mounting evidence for its competitive advantage over conventional techniques in major medical areas including oncology, cardiology, and neurology. Nuclear medicine is

  12. Nuclear medicine in China

    International Nuclear Information System (INIS)

    Since China first applied isotopes to medical research in 1956, over 800 hospitals and research institutions with 4000 staff have taken up nuclear technology. So far, over 120 important biologically active materials have been measured by radioimmunoassay in China, and 44 types of RIA kit have been supplied commercially. More than 50,000 cases of hyperthyroidism have been treated satisfactorily with 131I. Radionuclide imaging of practically all organs and systems of the human body has been performed, and adrenal imaging and nuclear cardiology have become routine clinical practice in several large hospitals. The thyroid iodine uptake test, renogram tracing and cardiac function studies with a cardiac probe are also commonly used in most Chinese hospitals. The active principles of more than 60 medicinal herbs have been labelled with isotopes in order to study the drug metabolism and mechanism of action. Through the use of labelled neurotransmitters or deoxyglucose, RIA, radioreceptor assay and autoradiography, Chinese researchers have made remarkable achievements in the study of the scientific basis of acupuncture analgesia. In 1980 the Chinese Society of Nuclear Medicine was founded, and since 1981 the Chinese Journal of Nuclear Medicine has been published. Although nuclear medicine in China has already made some progress, when compared with advanced countries, much progress is still to be made. It is hoped that international scientific exchange will be strengthened in the future. (author)

  13. Clinical applications of SPECT/CT: New hybrid nuclear medicine imaging system

    International Nuclear Information System (INIS)

    Interest in multimodality imaging shows no sign of subsiding. New tracers are spreading out the spectrum of clinical applications and innovative technological solutions are preparing the way for yet more modality marriages: hybrid imaging. Single photon emission computed tomography (SPECT) has enabled the evaluation of disease processes based on functional and metabolic information of organs and cells. Integration of X ray computed tomography (CT) into SPECT has recently emerged as a brilliant diagnostic tool in medical imaging, where anatomical details may delineate functional and metabolic information. SPECT/CT has proven to be valuable in oncology. For example, in the case of a patient with metastatic thyroid cancer, neither SPECT nor CT alone could identify the site of malignancy. SPECT/CT, a hybrid image, precisely identified where the surgeon should operate. However SPECT/CT is not just advantageous in oncology. It may also be used as a one-stop-shop for various diseases. Clinical applications with SPECT/CT have started and expanded in developed countries. It has been reported that moving from SPECT alone to SPECT/CT could change diagnoses in 30% of cases. Large numbers of people could therefore benefit from this shift all over the world. This report presents an overview of clinical applications of SPECT/CT and a relevant source of information for nuclear medicine physicians, radiologists and clinical practitioners. This information may also be useful for decision making when allocating resources dedicated to the health care system, a critical issue that is especially important for the development of nuclear medicine in developing countries. In this regard, the IAEA may be heavily involved in the promotion of programmes aimed at the IAEA's coordinated research projects and Technical Cooperation projects

  14. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... referring physician. top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations is ... risk is very low compared with the potential benefits. Nuclear medicine diagnostic procedures have been used for ...

  15. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Tell your doctor about your child’s recent illnesses, medical conditions, medications and allergies. Depending on the type ... Nuclear Medicine? Nuclear medicine is a branch of medical imaging that uses small amounts of radioactive material ...

  16. Nuclear energy and medicine

    International Nuclear Information System (INIS)

    The applications of nuclear energy on medicine, as well as the basic principles of these applications, are presented. The radiological diagnosis, the radiotherapy, the nuclear medicine, the radiological protection and the production of radioisotopes are studied. (M.A.C.)

  17. Nuclear medicine. Basic knowledge and clinical applications. 7. rev. and enl. ed.; Nuklearmedizin. Basiswissen und klinische Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Schicha, Harald [Universitaetsklinikum Koeln (Germany). Medizinisches Versorgungszentrum II; Schober, Otmar [Universitaetsklinikum Muenster (Germany). Klinik fuer Nuklearmedizin

    2013-11-01

    The book on basic knowledge and clinical applications of nuclear medicine covers the following issues: The first general part: principles of nuclear medicine; physical fundamentals; radiopharmaceutical chemistry; measuring techniques: gamma detectors, gamma spectrometry, gamma camera, SPECT, PET, PET/CT, PET/NMR, image processing and communication; nuclear medical examinations: metabolic and pharmacological kinetics, scintigraphic methods, criteria for the use; quality assurance; dosimetry and radiation protection, radiation risks and patients exposure, benefit-risk considerations. The second part covers endocrine organs, carcinomas, skeleton and bone joints, inflammations, lymph system, cardiovascular system, lungs, central nervous system, kidneys and urinary system, gastrointestinal tract, other scintigraphic examinations.

  18. Nuclear medicine physics

    CERN Document Server

    De Lima, Joao Jose

    2011-01-01

    Edited by a renowned international expert in the field, Nuclear Medicine Physics offers an up-to-date, state-of-the-art account of the physics behind the theoretical foundation and applications of nuclear medicine. It covers important physical aspects of the methods and instruments involved in modern nuclear medicine, along with related biological topics. The book first discusses the physics of and machines for producing radioisotopes suitable for use in conventional nuclear medicine and PET. After focusing on positron physics and the applications of positrons in medicine and biology, it descr

  19. Evaluating the fundamental qualities of a nuclear medicine radiographer for the provision of an optimal clinical service

    International Nuclear Information System (INIS)

    The developing nature of nuclear medicine practice highlights the need for an evaluation of the fundamental qualities of a Radiographer working within this discipline. Existing guidelines appear to be in place for clinical technologists working within nuclear medicine. However, limited guidance has been provided for Radiographers practicing within this discipline. This article aims to discuss the fundamental qualities that are considered essential for optimal service delivery, following consultation with various stakeholders. Areas such as technical expertise and knowledge, appropriate use of imaging equipment and current models of safe working practice will be discussed. Patient care and ethical considerations will also be evaluated, along with some core recommendations for future advanced practice.

  20. Tele-nuclear medicine

    OpenAIRE

    Nathanael Sabbah; Sinclair Wynchank

    2014-01-01

    This article presents a description of tele-nuclear medicine and, after outlining its history, a wide, representative range of its applications. Tele-nuclear medicine has benefited greatly from technological progress, which for several decades has provided greater data transfer rates and storage capacity at steadily decreasing cost. Differences in the practice of nuclear medicine between developed and developing countries arise mainly from disparities in their available infrastructure, fundin...

  1. Fundamentals of nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Alazraki, N.P.; Mishkin, F.S.

    1988-01-01

    The book begins with basic science and statistics relevant to nuclear medicine, and specific organ systems are addressed in separate chapters. A section of the text also covers imaging of groups of disease processes (eg, trauma, cancer). The authors present a comparison between nuclear medicine techniques and other diagnostic imaging studies. A table is given which comments on sensitivities and specificities of common nuclear medicine studies. The sensitivities and specificities are categorized as very high, high, moderate, and so forth.

  2. Fundamentals of nuclear medicine

    International Nuclear Information System (INIS)

    The book begins with basic science and statistics relevant to nuclear medicine, and specific organ systems are addressed in separate chapters. A section of the text also covers imaging of groups of disease processes (eg, trauma, cancer). The authors present a comparison between nuclear medicine techniques and other diagnostic imaging studies. A table is given which comments on sensitivities and specificities of common nuclear medicine studies. The sensitivities and specificities are categorized as very high, high, moderate, and so forth

  3. Technologists for Nuclear Medicine

    Science.gov (United States)

    Barnett, Huey D.

    1974-01-01

    Physicians need support personnel for work with radioisotopes in diagnosing dangerous diseases. The Nuclear Medicine Technology (NMT) Program at Hillsborough Community College in Tampa, Florida, is described. (MW)

  4. Nuclear medicine in vitro

    International Nuclear Information System (INIS)

    The subject is discussed under the following main headings: crystal scintillation counting; liquid scintillation counting; activation analysis; the in vitro nuclear medicine laboratory; blood volume in clinical practice B12 and folate deficiency; radionuclide studies associated with abnormalities of iron; basic principles of competitive radioassay; plasma cortisol; radioimmunoassays for T3 and T4; radioimmunoassay of estrogens; determination of androgens in biological fluids; radioimmunoassay of digitalis glycosides; growth hormone; thyrotropin; gonadotropins; radioimmunoassay of gastrin; glucagon; radioisotopic measurements of insulin; radioimmunoassay of the calcium-regulating hormones; the renin-angiotensin system and aldosterone; tumor antigens; fat absorption; protein-losing enteropathy; Australia antigen; bacteriologic cultures and sensitivities; and future pathways

  5. PACS in nuclear medicine

    International Nuclear Information System (INIS)

    PACS (Picture Archiving and Communication System) is being rapidly spread and installed in many hospitals, but most of the system do not include nuclear medicine field. Although additional costs of hardware for nuclear medicine PACS is low, the complexity in developing viewing software and little market have made the nuclear medicine PACS not popular. Most PACS utilize DICOM 3.0 as standard format, but standard format in nuclear medicine has been Interfile. Interfile should be converted into DICOM format if nuclear images are to be stored and visualized in most PACS. Nowadays, many vendors supply the DICOM option in gamma camera and PET. Several hospitals in Korea have already installed nucler PACS with DICOM, but only the screen captured images are supplied. Software for visualizing pseudo-color with color lookup tables and expressing with volume view should be developed to fulfill the demand of referring physicians and nuclear medicine physicians. PACS is going to integrate not only radiologic images but also endoscopic and pathologic images. Web and PC based PACS is now a trend and is much compatible with nuclear medicine PACS. Most important barrier for nuclear medicine PACS that we encounter is not a technical problem, but indifference of investor such as administrator of hospital or PACS. Now it is time to support and invest for the development of nuclear medicine PACS

  6. Quality control in Department of Nuclear Medicine, Clinical Center Banja Luka, RS, Bosnia and Herzegovina

    International Nuclear Information System (INIS)

    Complete test of publication follows. The aim of this work is to give a review of situations in the Department of Nuclear Medicine in Banja Luka related to quality control. We must perform daily, weekly and monthly control of equipment in the Department of Nuclear Medicine, and we must keep records. In our Department we have equipment from different producers and different year of production: 3 gamma cameras (1973, 1989, 2000); 2 auto gamma counters (2000, 2006); 2 dose calibrators (1973, 2000); 1 thyroid uptake system (2000). Normally procedures for quality control are also different. The situation, according to results of quality control is good. All equipment is working normally and with good performance (except one gamma camera - a problem with hard drive), but we don't have a routine daily control and periodical control for others tests. Keeping a records is another problem. Why? 1. In Bosnia and Herzegovina we don't have Regulatory authority. That means that we don't have legislation, rules, inspection or any other regulatory instruments. 2. There is only school for nurses, we have no special school for medical technician. So, we need an education in that field. 3. Very small number of physicist in hospital, no education for medical and nuclear medicine physicist. Conclusion. Situation in Department of Nuclear Medicine in Banja Luka related to quality control is on the medium level. We are trying to put that on the higher level, but to accomplish that we need additional education for nurses (technicians) and physicist.

  7. Rationale for the combination of nuclear medicine with magnetic resonance for pre-clinical imaging.

    Science.gov (United States)

    Wagenaar, Douglas J; Kapusta, Maciej; Li, Junqiang; Patt, Bradley E

    2006-08-01

    Multi-modality combinations of SPECT/CT and PET/CT have proven to be highly successful in the clinic and small animal SPECT/CT and PET/CT are becoming the norm in the research and drug development setting. However, the use of ionizing radiation from a high-resolution CT scanner is undesirable in any setting and particularly in small animal imaging (SAI), in laboratory experiments where it can result in radiation doses of sufficient magnitude that the experimental results can be influenced by the organism's response to radiation. The alternative use of magnetic resonance (MR) would offer a high-resolution, non-ionizing method for anatomical imaging of laboratory animals. MR brings considerably more than its 3D anatomical capability, especially regarding the imaging of laboratory animals. Dynamic MR imaging techniques can facilitate studies of perfusion, oxygenation, and diffusion amongst others. Further, MR spectroscopy can provide images that can be related to the concentration of endogenous molecules in vivo. MR imaging of injected contrast agents extends MR into the domain of molecular imaging. In combination with nuclear medicine (NM) SPECT and PET modalities in small animal imaging, MR would facilitate studies of dynamic processes such as biodistribution, pharmacokinetics, and pharmacodynamics. However, the detectors for nearly all PET and SPECT systems are still based on vacuum tube technology, namely: photomultiplier tubes (PMT's) in which the signal is generated by transporting electrons over a substantial distance within an evacuated glass tube, making them inoperable in even small magnetic fields. Thus the combination of SPECT or PET with MR has not been practical until the recent availability of semiconductor detectors such as silicon avalanche photodiodes (APD's) for PET and CdZnTe (CZT) detectors for SPECT coupled with the availability of high-density low noise ASIC electronics to read out the semiconductor detectors. The strong advantage of these

  8. E-film - an interactive clinical teaching tool for nuclear medicine

    International Nuclear Information System (INIS)

    Full text: With the advent of technology the old fashioned film library used by our Nuclear Medicine staff has been updated and remodelled from 'hard copy learning' with film and light boxes to 'soft-copy learning' using standard PC hardware and software. The new model 'e-film' is a web browser based image viewer written in HTML. It incorporates interesting case studies with interactive questions and answers based on pathology. The easy-to-use design involves selecting a Nuclear Medicine scan e g bone scan, and then the pathology of interest e g osteomyelitis. Each pathology selected has a normal and a number of abnormal cases, which can be viewed as static planar and dynamic images or as movies. The text displayed with each case study is a question with an answer that can be revealed when ready. A general learning tip pertaining to the scan type or particular pathology can also be revealed on request. Many of the case studies incorporate images from other modalities such as CT or MRI for comparison with the Nuclear Medicine images. Pre- and post- treatment scans can also be viewed to assess outcome 'e film' allows staff to search in a specific area of Nuclear Medicine and then test themselves on their understanding of the scan and relevant pathologies. Standard web browsers on PC's allow department-wide user accessibility of e-film via an intranet configuration. In summary, e-film is a convenient, time efficient way of learning with the potential of unlimited data expansion. Copyright (2002) The Australian and New Zealand Society of Nuclear Medicine Inc

  9. Your Radiologist Explains Nuclear Medicine

    Science.gov (United States)

    ... d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify disease in its ... abnormalities can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – ...

  10. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! ... d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify disease ...

  11. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... produced by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org ... I’d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify ...

  12. Historic images in nuclear medicine

    DEFF Research Database (Denmark)

    Hess, Søren; Høilund-Carlsen, Poul Flemming; Alavi, Abass

    2014-01-01

    In 1976, 2 major molecular imaging events coincidentally took place: Clinical Nuclear Medicine was first published in June, and in August researchers at the Hospital of the University of Pennsylvania created the first images in humans with F-FDG. FDG was initially developed as part of an evolution...... set in motion by fundamental research studies with positron-emitting tracers in the 1950s by Michel Ter-Pegossian and coworkers at the Washington University. Today, Clinical Nuclear Medicine is a valued scientific contributor to the molecular imaging community, and FDG PET is considered the backbone...

  13. Nuclear medicine and neurology

    International Nuclear Information System (INIS)

    Methods of nuclear medicine are based on the use of radioactive isotopes bound to specific marker substances. Administered radioactive markers enter metabolic processes. SPET and PET cameras enable, with their detectors, to register gamma quanta resulting from isotope decay, transform the absorbed quanta into visible light and process the registered signals by means of a computer system. Thus the functions of a living organism can be observed at the molecular level. Special markers capable of crossing the haematin-cephalic barrier and targeting neural metabolic processes are used for visualization of brain perfusion and neurotransmission at SPET and PET, serving for defection of diseases. These procedures are of special significance for the diagnosis of neurodegenerative diseases where the diagnostic value of anatomical-structural methods like CT and conventional MRI is low and where timely administration of proper neuroprotecfive measures contributes to improved disease management. SPET studies of brain perfusion enable to make early diagnosis of Alzheimer's disease due to typical perfusion defects which appear at the preclinical stage and allow to distinguish this disease from other dementia syndromes. Parkinson's disease has a latent period of 3-4 years before the clinical signs appear. SPET with dopamine receptors visualizes striatal dopaminergic presynaptic hypofunction providing the diagnosis at the early stage. Procedures of nuclear medicine enable to establish the differential diagnosis of various Parkinsonian syndromes. SPET and PET research helps to understand better pathophysiological processes, pharmacokinetics and pharmacodynamics in living organisms.(authors)

  14. Quantification Methods for Clinical Studies in Nuclear Medicine - Applications in AMS, PET/CT and SPECT/CT

    OpenAIRE

    Sydoff, Marie

    2013-01-01

    An essential part of the development of new radiopharmaceuticals for use in diagnostic nuclear medicine is the determination of its biokinetic properties. The uptake and turn-over of the radiopharmaceutical in the source organs is of great interest since this could determine whether the radiopharmaceutical would be suitable for clinical use or not. It is also important that the biokinetics and dosimetry of the radiopharmaceuticals is thoroughly investigated in order to determine the radiation...

  15. Analysis of the systems for management of radioactive wastes from nuclear medicine clinics of the city of Recife, Pernambuco, Brazil

    International Nuclear Information System (INIS)

    In nuclear medicine compounds marked with radionuclides, called radiopharmaceuticals, for obtention diagnostic information and for diseases treatment. The physicochemical characteristics of the radiopharmaceuticals determine his fixation at target-organ, and the physical characteristics determine the compound application in diagnostic or therapy. The handling of radiopharmaceuticals generates solid, liquid and gas wastes. The presence of these wastes implies in a adequate management according to regulation standards established by the Brazilian Nuclear Energy Commission (CNEN). The objective of safe management of radioactive wastes is to protect the human being and the preservation of the environment, limiting possible radiological impacts for the future generation, and comprehend a set of technical and administrative activities involved in the collection, segregation, handling, conditioning, transportation, storage, control and elimination, or the final deposition. This work intends to verify if the radioactive waste management systems from the nuclear medicine clinics at the city of Recife are conformal with te normative regulations issued by the CNEN. The initial obtained results are used to elaboration of conformal verification spreadsheet and its application in six nuclear medicine clinics at Recife

  16. Nuclear medicine in district general hospitals.

    OpenAIRE

    Staffurth, J. S.

    1983-01-01

    Nuclear medicine is a recognised clinical specialty both nationally and internationally. Compared with other countries, it is inadequately developed in Britain, particularly in district general hospitals. To create clinical radioisotope services at district level physicians or radiologists with experience in nuclear medicine need to be trained and appointed. Such appointments would allow facilities to evolve that would provide either a comprehensive nuclear medicine service formed around a ph...

  17. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... variety of diseases, including many types of cancers, heart disease, gastrointestinal, endocrine, neurological disorders and other abnormalities ... and bladder. bones. liver and gallbladder. gastrointestinal tract. heart. lungs. brain. thyroid. Nuclear medicine scans are typically ...

  18. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... after leaving the nuclear medicine facility. Through the natural process of radioactive decay, the small amount of radiotracer in your child’s body will lose its radioactivity over time. In many cases, the radioactivity will ...

  19. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... nuclear medicine imaging uses small amounts of radioactive materials called radiotracers, a special camera and a computer ... medical imaging that uses small amounts of radioactive material to diagnose and determine the severity of or ...

  20. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Videos related to Children's (Pediatric) Nuclear Medicine About this Site RadiologyInfo.org is produced by: Please note ... you can search the ACR-accredited facilities database . This website does not provide cost information. The costs ...

  1. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... not experience any discomfort. When swallowed, the radiotracer has little or no taste. If inhaled, your child ... after the nuclear medicine scan. If the child has been sedated, you will receive specific instructions to ...

  2. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations ... diagnosis or to determine appropriate treatment, if any. Risks Because the doses of radiotracer administered are small, ...

  3. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... referring physician. top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations is ... the possible charges you will incur. Web page review process: This Web page is reviewed regularly by ...

  4. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... after the procedure? Except for intravenous injections, most nuclear medicine procedures are painless and are rarely associated with significant discomfort or side effects. If the radiotracer is given intravenously, your child ...

  5. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... leaving the nuclear medicine facility. Through the natural process of radioactive decay, the small amount of radiotracer ... possible charges you will incur. Web page review process: This Web page is reviewed regularly by a ...

  6. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... nuclear medicine images can be superimposed with computed tomography (CT) or magnetic resonance imaging (MRI) to produce ... manufacturers are now making single photon emission computed tomography/computed tomography (SPECT/CT) and positron emission tomography/ ...

  7. Nuclear medicine pulmonary diagnosis

    International Nuclear Information System (INIS)

    Scintigraphic recording of regional ventilation and perfusion with 99mTc-Aerosol and 99mTc-MAA remain in the foreground of nuclear medicine pulmonary diagnostics. The most important indication for ventilation scintigraphy is the prediction of postoperative pulmonary function, which is still performed in many hospitals with perfusion scintigraphy, and with which, in turn, intrapulmonary right-left shunts can be simply and also semiquantitatively recorded. Combined ventilation/perfusion scintigraphy offers a very high degree of sensitivity in the proof of acute pulmonary embolism, is therefore exceptionally well suited for exclusion diagnostics, while specificity compared to pulmonary angiography and spiral CT still needs some clarification. The self-cleaning mechanism of the lung can be quantitatively examined using mucociliary and resorptive clearance. The clinical areas of application are limited for methodical reasons. Primary diagnostics of bronchial carcinoma and dignity differentiation of solitary pulmonary nodules, preferably with 18F-FDG PET are gaining steadily in importance. (orig.)

  8. Nuclear tele medicine; Telemedicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Vargas, L.; Hernandez, F.; Fernandez, R. [Departamento de Medicina Nuclear, Imagenologia Diagnostica, Xalapa, Veracruz (Mexico)

    2005-07-01

    The great majority of the digital images of nuclear medicine are susceptible of being sent through internet. This has allowed that the work in diagnosis cabinets by image it can benefit of this modern technology. We have presented in previous congresses works related with tele medicine, however, due to the speed in the evolution of the computer programs and the internet, becomes necessary to make a current position in this modality of work. (Author)

  9. Evolution of modern nuclear medicine tumor-imaging diagnostics in clinical oncology

    International Nuclear Information System (INIS)

    The evolution of current nuclear medicine diagnostic is closely related to the technical progress in imaging equipment development, and application of radiopharmaceuticals (Rphs) with a different tumor-uptake mechanism. It is the aim of the study to present groups of tumor-imaging Rphs differing by tumor uptake mechanisms, used in clinical oncology. The obtained results are described, and compared with the ones reported by other researchers. Sensitivity and specificity of Rphs for cardio-scintigraphy with 99mTc - MIBI and 201Tl are relatively high, amounting to 93.7% and 60% respectively, in the various tumors. These indicators depend on the stage, location, histopathology, level of malignancy and biological activity of the neoplasm. 99mTc - MIBI scintigraphy is endowed with considerable diagnostic potential for assaying multiple drug resistance (MDR), and is also a good criterion for its elimination following anti-MDR therapy. The obtained results show that radioimmunoscintigraphy (RIS) using different radiolabeled monoclonal antibodies (MoAb) have high sensitivity and specificity respectively: 86% and 80% in ovarian carcinoma with B72.3 antiTAG; 68.6% and 92.5% in colorectal carcinoma with B73.2 antiTAG, antiCEA, antiCA 19-9; 92% and 83% in breast cancer with antiCEA, 86.8% and 67-69% in malignant melanoma with 225.28s. Receptor scintigraphy may reach up to 86% sensitivity and 100% specificity in tumors saturated with somatostatin receptors. Positron emission tomography (PET) with 18F-FDG enhances the metabolic activity of tumor cells, and attains tumor-detecting rate amounting to 97%. Tumor imaging evolution characterized by the introduction and practical implementation of different Rphs, visualizing the functional and biochemical activity of tumor cells in the primary neoplasm, sentinel lymph nodes and distant metastases. radiolabelling of a variety of new biochemical substances, including DNA and RNA, drugs and lysosomes contributes to a successful imaging of

  10. Nuclear medicine applications for the diabetic foot

    Energy Technology Data Exchange (ETDEWEB)

    Hartshorne, M.F.; Peters, V.

    1987-04-01

    Although not frequently described in the podiatric literature, nuclear medicine imaging may be of great assistance to the clinical podiatrist. This report reviews in detail the use of modern nuclear medicine approaches to the diagnosis and management of the diabetic foot. Nuclear medicine techniques are helpful in evaluating possible osteomyelitis, in determining appropriate amputation levels, and in predicting response to conservative ulcer management. Specific indications for bone, gallium, and perfusion imaging are described.

  11. Nuclear tele medicine

    International Nuclear Information System (INIS)

    The great majority of the digital images of nuclear medicine are susceptible of being sent through internet. This has allowed that the work in diagnosis cabinets by image it can benefit of this modern technology. We have presented in previous congresses works related with tele medicine, however, due to the speed in the evolution of the computer programs and the internet, becomes necessary to make a current position in this modality of work. (Author)

  12. Nuclear medicine tomorrow

    International Nuclear Information System (INIS)

    The purpose of this Workshop was to discuss and promote future nuclear medicine applications. Atomic Energy of Canada Limited (AECL) is determined to assist in this role. A major aim of this gathering was to form an interface that was meaningful, representative of the two entities, and above all, on-going. In the opening address, given by Mr. J. Donnelly, President of AECL, this strong commitment was emphasized. In the individual sessions, AECL participants outlined R and D programs and unique expertise that promised to be of interest to members of the nuclear medicine community. The latter group, in turn, described what they saw as some problems and needs of nuclear medicine, especially in the near future. These Proceedings comprise the record of the formal presentations. Additionally, a system of reporting by rapporteurs insured a summary of informal discussions at the sessions and brought to focus pertinent conclusions of the workshop attendees

  13. Physics in nuclear medicine

    CERN Document Server

    Cherry, Simon R; Phelps, Michael E

    2012-01-01

    Physics in Nuclear Medicine - by Drs. Simon R. Cherry, James A. Sorenson, and Michael E. Phelps - provides current, comprehensive guidance on the physics underlying modern nuclear medicine and imaging using radioactively labeled tracers. This revised and updated fourth edition features a new full-color layout, as well as the latest information on instrumentation and technology. Stay current on crucial developments in hybrid imaging (PET/CT and SPECT/CT), and small animal imaging, and benefit from the new section on tracer kinetic modeling in neuroreceptor imaging.

  14. Development of software for clinical protocols in nuclear medicine. Final report for the period 21 November 1994 - 21 November 1995

    International Nuclear Information System (INIS)

    After two technical contracts of IAEA, a portable image processing software (PIP) has been developed and some clinical protocols for nuclear medicine studies with IBM PCs which are connected to analogue gamma cameras. In addition, a suitable front end for driving some PC/gamma camera interface cards have been successfully tested and extended. The on-line help facilities and the user interface within PIP was remarkably improved, for medical physicists as developers as well as for technologists as users for routine studies

  15. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... like? Special camera or imaging devices used in nuclear medicine include the gamma camera and single-photon emission-computed tomography (SPECT). The gamma camera, , also called a scintillation camera, detects radioactive energy that is emitted from the patient's body and ...

  16. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... diagnoses. In addition, manufacturers are now making single photon emission computed tomography/computed tomography (SPECT/CT) and ... nuclear medicine include the gamma camera and single-photon emission-computed tomography (SPECT). The gamma camera, , also ...

  17. Nuclear Medicine in India

    Directory of Open Access Journals (Sweden)

    R.D. Lele

    1990-10-01

    Full Text Available The regular supply of radiopharmaceuticals and radioimmunoassay kits from BARC has been an important factor in the development of nuclear medicine in India. However, a major stumbling block has been the non-availability of suitable instrumentation systems (especially the computer-assisted gamma camera at an affordable price. Two recent developments, viz., the creation of the Board of Radioisotope Technology by the Department of Atomic Energy, and the efforts of Electronic Corporation of India Ltd. to design indigenously a gamma camera with a computer attachment, hold promise for the future healthy and rapid growth of nuclear medicine in the country. Training in nuclear medicine at the post-graduate level is gradually picking up. Nuclear medicine is essentially applied physiology and biochemistry, and provides an orientation, different from those of the anatomist and physiologist. The gamma camera, SPECT and PET enable the study of dynamic metabolic function resolution to spatial and temporal resolutions. Newer developments in tagged monoclonal antibodies hold promise for a better understanding of infectious and inflammatory disease which are a burden in the developing countries.

  18. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... pictures and provides molecular information. In many centers, nuclear medicine images can be superimposed with computed tomography (CT) or magnetic resonance imaging (MRI) to produce special views, a practice known as image fusion or co-registration. These views allow the information ...

  19. Nuclear techniques in medicine

    International Nuclear Information System (INIS)

    Nuclear physics has played a large role in medical treatment and diagnosis, from the technologies used in nuclear physics experiments to nuclear reactions. Particle detector technology from experimental nuclear and particle physics is the basis of the various tomographic imaging modalities such as: the radioactive tracers used in nuclear medicine result from neutron induced reactions using nuclear reactor facilities; cyclotron production of short-lived isotopes which allows metabolism of brain and cardiac tissue to be measured; in-vivo neutron activation analysis which allows the measurement of trace elements in the body. The purpose of this presentation is to illustrate some of those techniques such as, particle-beam treatments, neutron activation analyses, magnetic resonance imaging, and the physics involved. 5 figs., 1 tab., ills

  20. Central nervous system assessment in nuclear medicine. Clinical aspects: tracers and indications

    International Nuclear Information System (INIS)

    Nuclear neuroimaging techniques allow the study of functional and neurochemical aspects of the human brain in vivo. SPECT (Single Photon Emission Computed Tomography) as well as PET (Positron Emission Tomography) are non-invasive techniques which present two modalities: functional and biochemical. The functional one provides information about neuronal activity measured through metabolism (PET) or regional brain perfusion (SPECT, RMN f). Biochemical neuroimaging provides information on the chemical substrates involved in neurotransmission (receptors, transporters and enzymes) and allows the study of the synaptic activity through imaging of the different brain regions. This information about neurochemical aspects of neurotransmission is an exclusive field of nuclear neuroimaging techniques SPECT and PET. In this paper we discuss the tracers used for each modality of brain SPECT as well as their main clinical uses. (author)

  1. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Uterine Fibroids Dementia Video: General Ultrasound Video: Pediatric Nuclear Medicine Radiology and You About this Site RadiologyInfo. ... produced by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org ...

  2. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Fibroids Dementia Video: General Ultrasound Video: Pediatric Nuclear Medicine Radiology and You About this Site RadiologyInfo.org ... by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! ...

  3. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... this Site RadiologyInfo.org is produced by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome ... Recently posted: Focused Ultrasound for Uterine Fibroids Dementia Video: General Ultrasound Video: Pediatric Nuclear Medicine Radiology and ...

  4. Nuclear medicine technology study guide

    CERN Document Server

    Patel, Dee

    2011-01-01

    Nuclear Medicine Technology Study Guide presents a comprehensive review of nuclear medicine principles and concepts necessary for technologists to pass board examinations. The practice questions and content follow the guidelines of the Nuclear Medicine Technology Certification Board (NMTCB) and American Registry of Radiological Technologists (ARRT), allowing test takers to maximize their success in passing the examinations. The book is organized by sections of increasing difficulty, with over 600 multiple-choice questions covering all areas of nuclear medicine, including radiation safety; radi

  5. Comparison of 4-Dimensional Computed Tomography Ventilation With Nuclear Medicine Ventilation-Perfusion Imaging: A Clinical Validation Study

    Energy Technology Data Exchange (ETDEWEB)

    Vinogradskiy, Yevgeniy, E-mail: yevgeniy.vinogradskiy@ucdenver.edu [Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado (United States); Koo, Phillip J. [Department of Radiology, University of Colorado School of Medicine, Aurora, Colorado (United States); Castillo, Richard [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Castillo, Edward; Guerrero, Thomas [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Department of Computational and Applied Mathematics, Rice University, Houston, Texas (United States); Gaspar, Laurie E.; Miften, Moyed; Kavanagh, Brian D. [Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, Colorado (United States)

    2014-05-01

    Purpose: Four-dimensional computed tomography (4DCT) ventilation imaging provides lung function information for lung cancer patients undergoing radiation therapy. Before 4DCT-ventilation can be implemented clinically it needs to be validated against an established imaging modality. The purpose of this work was to compare 4DCT-ventilation to nuclear medicine ventilation, using clinically relevant global metrics and radiologist observations. Methods and Materials: Fifteen lung cancer patients with 16 sets of 4DCT and nuclear medicine ventilation-perfusion (VQ) images were used for the study. The VQ-ventilation images were acquired in planar mode using Tc-99m-labeled diethylenetriamine-pentaacetic acid aerosol inhalation. 4DCT data, spatial registration, and a density-change-based model were used to compute a 4DCT-based ventilation map for each patient. The percent ventilation was calculated in each lung and each lung third for both the 4DCT and VQ-ventilation scans. A nuclear medicine radiologist assessed the VQ and 4DCT scans for the presence of ventilation defects. The VQ and 4DCT-based images were compared using regional percent ventilation and radiologist clinical observations. Results: Individual patient examples demonstrate good qualitative agreement between the 4DCT and VQ-ventilation scans. The correlation coefficients were 0.68 and 0.45, using the percent ventilation in each individual lung and lung third, respectively. Using radiologist-noted presence of ventilation defects and receiver operating characteristic analysis, the sensitivity, specificity, and accuracy of the 4DCT-ventilation were 90%, 64%, and 81%, respectively. Conclusions: The current work compared 4DCT with VQ-based ventilation using clinically relevant global metrics and radiologist observations. We found good agreement between the radiologist's assessment of the 4DCT and VQ-ventilation images as well as the percent ventilation in each lung. The agreement lessened when the data were

  6. Comparison of 4-Dimensional Computed Tomography Ventilation With Nuclear Medicine Ventilation-Perfusion Imaging: A Clinical Validation Study

    Science.gov (United States)

    Vinogradskiy, Yevgeniy; Koo, Phillip J.; Castillo, Richard; Castillo, Edward; Guerrero, Thomas; Gaspar, Laurie E.; Miften, Moyed; Kavanagh, Brian D.

    2014-01-01

    Purpose Four-dimensional computed tomography (4DCT) ventilation imaging provides lung function information for lung cancer patients undergoing radiation therapy. Before 4DCT-ventilation can be implemented clinically it needs to be validated against an established imaging modality. The purpose of this work was to compare 4DCT-ventilation to nuclear medicine ventilation, using clinically relevant global metrics and radiologist observations. Methods and Materials Fifteen lung cancer patients with 16 sets of 4DCT and nuclear medicine ventilation-perfusion (VQ) images were used for the study. The VQ-ventilation images were acquired in planar mode using Tc-99m-labeled diethylenetriamine-pentaacetic acid aerosol inhalation. 4DCT data, spatial registration, and a density-change-based model were used to compute a 4DCT-based ventilation map for each patient. The percent ventilation was calculated in each lung and each lung third for both the 4DCT and VQ-ventilation scans. A nuclear medicine radiologist assessed the VQ and 4DCT scans for the presence of ventilation defects. The VQ and 4DCT-based images were compared using regional percent ventilation and radiologist clinical observations. Results Individual patient examples demonstrate good qualitative agreement between the 4DCT and VQ-ventilation scans. The correlation coefficients were 0.68 and 0.45, using the percent ventilation in each individual lung and lung third, respectively. Using radiologist-noted presence of ventilation defects and receiver operating characteristic analysis, the sensitivity, specificity, and accuracy of the 4DCT-ventilation were 90%, 64%, and 81%, respectively. Conclusions The current work compared 4DCT with VQ-based ventilation using clinically relevant global metrics and radiologist observations. We found good agreement between the radiologist’s assessment of the 4DCT and VQ-ventilation images as well as the percent ventilation in each lung. The agreement lessened when the data were analyzed

  7. Comparison of 4-Dimensional Computed Tomography Ventilation With Nuclear Medicine Ventilation-Perfusion Imaging: A Clinical Validation Study

    International Nuclear Information System (INIS)

    Purpose: Four-dimensional computed tomography (4DCT) ventilation imaging provides lung function information for lung cancer patients undergoing radiation therapy. Before 4DCT-ventilation can be implemented clinically it needs to be validated against an established imaging modality. The purpose of this work was to compare 4DCT-ventilation to nuclear medicine ventilation, using clinically relevant global metrics and radiologist observations. Methods and Materials: Fifteen lung cancer patients with 16 sets of 4DCT and nuclear medicine ventilation-perfusion (VQ) images were used for the study. The VQ-ventilation images were acquired in planar mode using Tc-99m-labeled diethylenetriamine-pentaacetic acid aerosol inhalation. 4DCT data, spatial registration, and a density-change-based model were used to compute a 4DCT-based ventilation map for each patient. The percent ventilation was calculated in each lung and each lung third for both the 4DCT and VQ-ventilation scans. A nuclear medicine radiologist assessed the VQ and 4DCT scans for the presence of ventilation defects. The VQ and 4DCT-based images were compared using regional percent ventilation and radiologist clinical observations. Results: Individual patient examples demonstrate good qualitative agreement between the 4DCT and VQ-ventilation scans. The correlation coefficients were 0.68 and 0.45, using the percent ventilation in each individual lung and lung third, respectively. Using radiologist-noted presence of ventilation defects and receiver operating characteristic analysis, the sensitivity, specificity, and accuracy of the 4DCT-ventilation were 90%, 64%, and 81%, respectively. Conclusions: The current work compared 4DCT with VQ-based ventilation using clinically relevant global metrics and radiologist observations. We found good agreement between the radiologist's assessment of the 4DCT and VQ-ventilation images as well as the percent ventilation in each lung. The agreement lessened when the data were

  8. Nuclear medicine at the crossroads

    Energy Technology Data Exchange (ETDEWEB)

    Strauss, H.W. [Stanford Univ. Hospital, Div. of Nuclear Medicine, CA (United States)

    1996-06-01

    Many nuclear medicine procedures, originally developed more than 20 years ago, are now performed with new radiopharmaceuticals or instruments; it is therefore apposite to reappraise what we are doing and why we are doing it. The clinical utility of nuclear medicine is discussed with reference, by way of example, to gated blood pools scans and myocardial perfusion imaging; the importance of the referred population for the outcome of studies is stressed. Attention is drawn to the likelohood that the detection of ischemia would be enhanced by the administration of nitroglycerin prior to rest thallium injection. Emphasis is also placed on the increasing acceptance of dual-tracer studies. The significance of expression of p-glycoprotein by some tumors for sestamibi imaging is discussed, and advances in respect of fluorodeoxyglucose imaging are reviewed. The final section covers issues relating to the development of new procedures, such as the value of nuclear medicine in the detection and characterization of tissue oxygen levels and the possible future role of nuclear medicine in the management of sleeping and eating disorders. (orig.)

  9. Nuclear medicine at the crossroads

    International Nuclear Information System (INIS)

    Many nuclear medicine procedures, originally developed more than 20 years ago, are now performed with new radiopharmaceuticals or instruments; it is therefore apposite to reappraise what we are doing and why we are doing it. The clinical utility of nuclear medicine is discussed with reference, by way of example, to gated blood pools scans and myocardial perfusion imaging; the importance of the referred population for the outcome of studies is stressed. Attention is drawn to the likelohood that the detection of ischemia would be enhanced by the administration of nitroglycerin prior to rest thallium injection. Emphasis is also placed on the increasing acceptance of dual-tracer studies. The significance of expression of p-glycoprotein by some tumors for sestamibi imaging is discussed, and advances in respect of fluorodeoxyglucose imaging are reviewed. The final section covers issues relating to the development of new procedures, such as the value of nuclear medicine in the detection and characterization of tissue oxygen levels and the possible future role of nuclear medicine in the management of sleeping and eating disorders. (orig.)

  10. Nuclear medicine in sports

    International Nuclear Information System (INIS)

    Nuclear medicine can synergistically contribute to the sports medicine field, in the management of sports-related stress injures. Bone scintigraphy is commonly requested for evaluation of athletes with pain. Three-Phase 99mTc MDP Bone Scan has emerged as the imaging reference standard for diagnosing such injuries. The inherently high-contrast resolution of the bone scan allows early detection of bone trauma and becomes positive within six to seventy-two hours after the onset of symptoms. The bone scan is able to demonstrate stress injuries days to weeks before the radiograph

  11. Efficacy of clinical diagnostic procedures utilized in nuclear medicine. Technical progress report, 1 December 1981-30 November 1982

    International Nuclear Information System (INIS)

    The efficacy of nuclear medicine diagnostic procedures was measured. Three levels of efficacy were defined. However, two different methods of evaluating efficacy itself were first compared. Using two methods, logistic regression and entropy-minimax pattern detection, substantial agreement was found between them in several clinical observations. (1) There are no attributes that indicate that any grouping of symptoms, signs, and laboratory findings is capable of suggesting that a patient does or does not have a pulmonary embolus. (2) The lung scan test is the only reliable method which indicates that a patient may have a pulmonary embolus or does not have a pulmonary embolus. (3) The validity of these conclusions and the ability to apply them widely to ongoing clinical practice is based on the prospective design of the Study which included an appropriate distribution of institutions by type, size, and geographic location. Also, the only judgement samples was that of the referring physician

  12. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify disease in its ... abnormalities can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – ...

  13. Place of the nuclear medicine in the clinical development of the gene therapy

    International Nuclear Information System (INIS)

    Although gene therapy has been proposed first for genetic diseases, its concept has been extended to many acquired diseases, owing to a better understanding of pathology at a molecular level. Overall, very few trials have shown to be efficient, and safety concerns have emerged, as a result of several patients deaths. There is a need for new techniques able to improve both the knowledge of the therapeutic gene fate once administered and the early detection of events likely to lead to serious adverse events. In vivo imaging of a reporter gene associated with the therapeutic one is certainly the most promising technique for these goals. Among available imaging modalities, nuclear imaging is the most likely to be applied to patients. This review begins with a summary of current knowledge about the steps that a therapeutic gene has to cross from vector delivery to appropriate expression in target cells. We show how gene imaging could allow to investigate many pitfalls of trials by providing a better understanding of these steps in patients. The reporter genes available for nuclear imaging are presented in the second section, through animal studies. Then, relevant examples of clinical trials are presented. These include cancer (suicide gene therapy and adoptive immunotherapy), ischemic heart diseases and cystic fibrosis. The results are commented with emphasis on the role of nuclear imaging to address the questions raised by these studies, and imaging studies carried out on animals or patients for the corresponding diseases or organs are presented. The results obtained in animal studies warrant the introduction of gene imaging in clinical trials. (authors)

  14. Defining user requirements for tele-nuclear medicine applications: from technical feasibility to clinical results

    International Nuclear Information System (INIS)

    Purpose: Defining the user requirements for tele-nuclear medicine systems, in particular in developing countries, is an important prerequisite to establishing a service. However, the availability of low cost PC based servers and, now, access to local ISPs, has made the technical provision of such networks relatively simple and low cost, although transfer of data to and form legacy systems still present many difficulties. Method and Materials: The key driving force in developing countries is the imbalance between skills in the relatively few centres of excellence and the increasing number of installations overall. Requirements include both very rapid remote reporting and/or overnight tele-consultation. Original raw NM data must be available not just 'images'. Using current network standards (VPN) data transfer rate requirements are low. Provision of image fusion between NM, CT and MRI is also highly desirable. Results: Experience has been obtained e.g. in Thailand and Morocco, where a network of servers and remote users, with cardiac application of particular importance, has demonstrated benefit, and increasing volumes of usage. Conclusions: However, the requirements need to be clearly defined, and a staff training program is essential, as is a full evaluation. The transfer of skills is important in raising the overall quality of health care

  15. Optimisation of protection in nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine is a branch of clinical medicine, which is concerned mainly with the use of unsealed sources of radionuclides for various diagnostic and therapeutic applications. The purpose of this paper is to acquaint with the essential principles and procedures of radiation protection, so that nuclear medicine procedures are performed in a manner by which the radiation exposure to the patient, staff and public are kept as low as reasonably achievable (ALARA). The philosophy of radiation protection in nuclear medicine involves protection of the patient, of the staff and the public

  16. Prospects in nuclear medicine

    International Nuclear Information System (INIS)

    In nuclear medicine, a sequence of revolutioning research up to the simple and efficient application in routine has always then taken place when in an interdisciplinary teamwork new radiochemical tracers and/or new instrumentation had become available. At present we are at the beginning of a phase that means to be in-vivo-biochemistry, the targets of which are molecular interactions in the form of enzymatic reactions, ligand-receptor interactions or immunological reactions. The possibility to use positron-emitting radionuclides of bioelements in biomolecules or drugs to measure their distribution in the living organism by positron-emission tomography (PET) is gaining admittance into the pretentious themes of main directions of medical research. Diagnostic routine application of biochemically oriented nuclear medicine methods are predominantly expected from the transmission of knowledge in PET research to the larger appliable emission tomography with gamma-emitting tracers (SPECT). (author)

  17. Imaging in nuclear medicine

    CERN Document Server

    Hoeschen, Christoph

    2013-01-01

    This volume addresses a wide range of issues in the field of nuclear medicine imaging, with an emphasis on the latest research findings. Initial chapters set the scene by considering the role of imaging in nuclear medicine from the medical perspective and discussing the implications of novel agents and applications for imaging. The physics at the basis of the most modern imaging systems is described, and the reader is introduced to the latest advances in image reconstruction and noise correction. Various novel concepts are then discussed, including those developed within the framework of the EURATOM FP7 MADEIRA research project on the optimization of imaging procedures in order to permit a reduction in the radiation dose to healthy tissues. Advances in quality control and quality assurance are covered, and the book concludes by listing rules of thumb for imaging that will be of use to both beginners and experienced researchers.

  18. Nuclear medicine and gastroenterology

    International Nuclear Information System (INIS)

    A Symposium with the topic 'Nuclear Medicine and Gastroenterology' was held on the occasion of the annual meeting 1976 of the Rheinisch-Westfalische Gesellschaft fuer Nuklearmedizin, led by Professor Dr.W. Stroetges in the Klinicum of the University of Essen. The meeting report first deals with some well-established examination methods which, however, still need some explanation concerning their diagnostical-patho-physiological background. Then some problems are shown which might be solved with the help of nuclear medicine. 1) Exsudative enteropathy, 2) The problem of the blind loop with bacteria proliferation and its relations to gall acid metabolism, 3) Functional examination of the distal small intestine with absorption of vitamin B12; 4) Some special problems. (orig.)

  19. Nuclear medicine therapy

    CERN Document Server

    Eary, Janet F

    2013-01-01

    One in three of the 30 million Americans who are hospitalized are diagnosed or treated with nuclear medicine techniques. This text provides a succinct overview and detailed set of procedures and considerations for patient therapy with unsealed radioactivity sources.  Serving as a complete literature reference for therapy with radiopharmaceuticals currently utilized in practice, this source covers the role of the physician in radionuclide therapy, and essential procedures and protocols required by health care personnel.

  20. Veterinary nuclear medicine

    International Nuclear Information System (INIS)

    The veterinary use of radionuclide techniques dates back to the mid-sixties, but its more extensive use dates back to the past two decades. Veterinary nuclear medicine is focused mainly on four major issues: bone scintigraphy - with the majority of applications in horses, veterinary endocrinology - dealing mainly with the problems of hyperthyreosis in cats and hyperthyreosis in dogs, portosystemic shunts in small animals and veterinary oncology, however, most radionuclide techniques applied to humans can be applied to most animals. (author)

  1. Imaging in nuclear medicine

    International Nuclear Information System (INIS)

    Presents the most recent developments in nuclear medicine imaging, with emphasis on the latest research findings. Considers the latest advances in imaging systems, image reconstruction, noise correction, and quality assurance. Discusses novel concepts, including those developed within the framework of the EURATOM FP7 MADEIRA project. Lists rules of thumb for imaging of use to both beginners and experienced researchers. This volume addresses a wide range of issues in the field of nuclear medicine imaging, with an emphasis on the latest research findings. Initial chapters set the scene by considering the role of imaging in nuclear medicine from the medical perspective and discussing the implications of novel agents and applications for imaging. The physics at the basis of the most modern imaging systems is described, and the reader is introduced to the latest advances in image reconstruction and noise correction. Various novel concepts are then discussed, including those developed within the framework of the EURATOM FP7 MADEIRA research project on the optimization of imaging procedures in order to permit a reduction in the radiation dose to healthy tissues. Advances in quality control and quality assurance are covered, and the book concludes by listing rules of thumb for imaging that will be of use to both beginners and experienced researchers.

  2. Imaging in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Giussani, Augusto [BfS - Federal Office for Radiation Protection, Oberschleissheim (Germany). Dept. of Radiation Protection and Health; Hoeschen, Christoph (eds.) [Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg (Germany). Research Unit Medical Raditation Physics and Diagnostics

    2013-08-01

    Presents the most recent developments in nuclear medicine imaging, with emphasis on the latest research findings. Considers the latest advances in imaging systems, image reconstruction, noise correction, and quality assurance. Discusses novel concepts, including those developed within the framework of the EURATOM FP7 MADEIRA project. Lists rules of thumb for imaging of use to both beginners and experienced researchers. This volume addresses a wide range of issues in the field of nuclear medicine imaging, with an emphasis on the latest research findings. Initial chapters set the scene by considering the role of imaging in nuclear medicine from the medical perspective and discussing the implications of novel agents and applications for imaging. The physics at the basis of the most modern imaging systems is described, and the reader is introduced to the latest advances in image reconstruction and noise correction. Various novel concepts are then discussed, including those developed within the framework of the EURATOM FP7 MADEIRA research project on the optimization of imaging procedures in order to permit a reduction in the radiation dose to healthy tissues. Advances in quality control and quality assurance are covered, and the book concludes by listing rules of thumb for imaging that will be of use to both beginners and experienced researchers.

  3. ECAT ART - a continuously rotating PET camera: performance characteristics, initial clinical studies, and installation considerations in a nuclear medicine department

    International Nuclear Information System (INIS)

    Advances in image reconstruction techniques have permitted the development of a commercial, rotating, partial ring, fully 3D scanner, the ECAT ART. The system has less than one-half the number of bismuth germanate detectors compared with a full ring scanner with the equivalent field of view, resulting in reduced capital cost. The performance characteristics, implications for installation in a nuclear medicine department, and clinical utility of the scanner are presented in this report. The sensitivity (20 cm diameter x 20 cm long cylindrical phantom, no scatter correction) is 11400 cps.kBq-1.ml-1. This compares with 5800 and 40500 cps.kBq-1.ml-1in 2D and 3D respectively for the equivalent full ring scanner (ECAT EXACT). With an energy window of 350-650 keV the maximum noise equivalent count (NEC) rate was 27 kcps at a radioactivity concentration of ∝15 kBq .ml -1in the cylinder. Spatial resolution is ∝6 mm full width at half maximum on axis degrading to just under 8 mm at a distance of 20 cm off axis. Installation and use within the nuclear medicine department does not appreciably increase background levels of radiation on gamma cameras in adjacent rooms and the dose rate to an operator in the same room is 2 μSv .h -1for a typical fluorine-18 fluorodeoxyglucose (18F-FDG) study with an initial injected activity of 370 MBq. The scanner has been used for clinical imaging with 18F-FDG for neurological and oncological applications. Its novel use for imaging iron-52 transferrin for localising erythropoietic activity demonstrates its sensitivity and resolution advantages over a conventional dual-headed gamma camera. The ECAT ART provides a viable alternative to conventional full ring PET scanners without compromising the performance required for clinical PET imaging. (orig.). With 9 figs., 3 tabs

  4. Radionuclides in diagnostic nuclear medicine

    International Nuclear Information System (INIS)

    Diagnostic Nuclear Medicine (NM) is an essential procedure in modern medical practice. Recent survey reported that more than 2 million NM examinations are conducted every year in Japan. Around 75% of diagnostic NM employs single photon emission tomography (SPECT) with 99mTc, 123I, 133Xe, or 201Tl-labeled compound, and 25% positron emission tomography (PET) with 18F-fluorodeoxy glucose, 15O-labeled H2O, CO, O2, or 11C-labeled compounds. Modern medicine is based on the intervention of molecular pathology of the diseases. Therefore, NM is expanding in number and in quality in daily medical practice including early diagnosis of Alzheimer’s diseases, cancer, and cardiovascular diseases, strategy decision of treatment, evaluation of regeneration medicine. Furthermore, the NM is being utilized to facilitate new drug development. Combining molecular diagnosis with radionuclide therapy (Theranostics) is another future direction of clinical NM. (author)

  5. Radiation protection in nuclear medicine

    International Nuclear Information System (INIS)

    The goal of this Chapter is to give a general outline of the essential principles and procedures for radiation protection in a nuclear medicine department where radionuclides are used for diagnosis and therapy. More detailed recommendations regarding radiation protection in nuclear medicine are given in the publications of the International Commission on Radiation Protection (ICRP, publications 25, 57, 60) and in ILO/IAEA/WHO Manual on Radiation Protection in Hospitals and General Practice (Volume 2: Unsealed Sources, WHO, Geneva, 1975), on which this Chapter is based. This chapter is not intended to replace the above-mentioned international recommendations on radiation protection, as well as existing national regulations on this subject, but intended only to provide guidance for implementing these recommendations in clinical practice

  6. Frontiers in nuclear medicine symposium: Nuclear medicine & molecular biology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    This document contains the abstracts from the American College of Nuclear Physicians 1993 Fall Meeting entitled, `Frontiers in Nuclear Medicine Symposium: Nuclear Medicine and Molecular Biology`. This meeting was sponsored by the US DOE, Office of Health and Environmental Research, Office of Energy Research. The program chairman was Richard C. Reba, M.D.

  7. Nuclear medicine statistics

    International Nuclear Information System (INIS)

    Numerical description of medical and biologic phenomena is proliferating. Laboratory studies on patients now yield measurements of at least a dozen indices, each with its own normal limits. Within nuclear medicine, numerical analysis as well as numerical measurement and the use of computers are becoming more common. While the digital computer has proved to be a valuable tool for measurment and analysis of imaging and radioimmunoassay data, it has created more work in that users now ask for more detailed calculations and for indices that measure the reliability of quantified observations. The following material is presented with the intention of providing a straight-forward methodology to determine values for some useful parameters and to estimate the errors involved. The process used is that of asking relevant questions and then providing answers by illustrations. It is hoped that this will help the reader avoid an error of the third kind, that is, the error of statistical misrepresentation or inadvertent deception. This occurs most frequently in cases where the right answer is found to the wrong question. The purposes of this chapter are: (1) to provide some relevant statistical theory, using a terminology suitable for the nuclear medicine field; (2) to demonstrate the application of a number of statistical methods to the kinds of data commonly encountered in nuclear medicine; (3) to provide a framework to assist the experimenter in choosing the method and the questions most suitable for the experiment at hand; and (4) to present a simple approach for a quantitative quality control program for scintillation cameras and other radiation detectors

  8. Nuclear medicine radiation dosimetry

    CERN Document Server

    McParland, Brian J

    2010-01-01

    Complexities of the requirements for accurate radiation dosimetry evaluation in both diagnostic and therapeutic nuclear medicine (including PET) have grown over the past decade. This is due primarily to four factors: growing consideration of accurate patient-specific treatment planning for radionuclide therapy as a means of improving the therapeutic benefit, development of more realistic anthropomorphic phantoms and their use in estimating radiation transport and dosimetry in patients, design and use of advanced Monte Carlo algorithms in calculating the above-mentioned radiation transport and

  9. Nuclear medicine in cardiology

    Energy Technology Data Exchange (ETDEWEB)

    Torizuka, K.; Ishii, Y.; Yonekura, Y.; Yamamoto, K.; Tamaki, N. (Kyoto Univ. (Japan). Faculty of Medicine)

    1981-02-01

    Nuclear medicine in cardiology was reviewed. Electrocardiogram is obtained from the ..gamma..-ray measurement of a tracer by a single detector, which enables a bedsidemonitoring. Resolution and sensitivity are high and nuclear stethoscope with a computer is applicable for a background treatment. Myocardium is imaged by /sup 201/Tl scintigraphy. Relative difference of the perfusion indicates the ischemia which gaives roughly the size and portion of myocardial infarction. For transient ischemia stress myocardial perfusion imaging (SMPI) is also used. sup(99m)Tc pyrophosphate provides a clear image for myocardial infarction. Angiocardiogram is obtained repeatedly, by a single administration, using an equilibrium method. An attempt of three-dimensional display by 7 pin hole collimator and positron CT are also discussed.

  10. Nuclear medicine in cardiology

    International Nuclear Information System (INIS)

    Nuclear medicine in cardiology was reviewed. Electrocardiogram is obtained from the γ-ray measurement of a tracer by a single detector, which enables a bedsidemonitoring. Resolution and sensitivity are high and nuclear stethoscope with a computer is applicable for a background treatment. Myocardium is imaged by 201Tl scintigraphy. Relative difference of the perfusion indicates the ischemia which gaives roughly the size and portion of myocardial infarction. For transient ischemia stress myocardial perfusion imaging (SMPI) is also used. sup(99m)Tc pyrophosphate provides a clear image for myocardial infarction. Angiocardiogram is obtained repeatedly, by a single administration, using an equilibrium method. An attempt of three-dimensional display by 7 pin hole collimator and positron CT are also discussed. (Nakanishi, T.)

  11. Nuclear Medicine week in Colombia

    International Nuclear Information System (INIS)

    During the week of 6-12 October 2003 the IAEA organized a Research Coordination Meeting on 'Relationship between lower Respiratory Tract Infection, Gastroesophageal reflux and bronchial Asthma in children' at Hospital San Ignacio in Bogota. Besides there were four workshops in Bogota; workshops on Bone infection and Bone scan in Pediatric ortopaedics at Hospital Militar and Fundacion CardioInfantil, a workshop for Nuclear Medicine Technologists and a workshop on Sentinel Lymph Node mapping and Surgical Gamma Probe Application at Institute of Oncology. A nuclear cardiology workshop was organized in Medellin, and finally crowning them all was the 9th Congress of the Colombian Association of Nuclear Medicine at Cali from 10-12 October, 2003; probably the largest and best Colombian nuclear medicine congress every held in the country. A workshop was also organized in Cali for nuclear medicine technologists in conjunction with the Annual Convention. It was a mix of IAEA's Technical Cooperation and Regular Budget activities along with the activities of Colombian Association of Nuclear Medicine, bringing in absolute synergy to galvanize the entire nuclear medicine community of the country. The week saw nuclear medicine scientists from more than 20 IAEA Member States converging on Colombia to spread the message of nuclear medicine, share knowledge and to foster International understanding and friendship among the nuclear medicine people of the world

  12. Systems and signal processing in nuclear medicine

    International Nuclear Information System (INIS)

    Proceedings covering all lectures presented to the 7th Spring Meeting of Deutsche Gesellschaft fuer Med. Dokumentation, Informatik und Statistik, GMDS, on the subject of ''Systems and signal processing in nuclear medicine''. Currently available systems for nuclear medicine and their application in administration, documentation and clinical routine examinations are dealt with in the first part. Three papers discuss various methods of signal processing, and methods of automatic image processing are dealt with at length. Trends of development are discussed, and the situation of nuclear medicine in various European countries is reviewed. (WU)

  13. Nuclear medicine and AIDS

    International Nuclear Information System (INIS)

    The human immunodeficiency virus (HIV) infection and its associated illnesses in a relatively young population of patients provides an expanding role for nuclear medicine. The disease enforces a review of each department's infection control procedures. It has also resulted in an increase in the number of patients presenting with diseases such as Pneumocystis carinii pneumonia, Kaposi's sarcoma etc. which prior to the HIV epidemic were extremely rare. Thus in high risk patients the interpretation of abnormalities in nuclear medicine scans needs to include the spectrum of opportunistic infections and unusual tumours. The presence of opportunistic infections in the severely immunocompromised patient has led to the development of techniques not normally used, i.e. lung 99Tcm-diethylenetriamine pentaacetate (DTPA) transfer/clearance, donor leukocyte scanning to allow rapid diagnosis of an abnormality. Radionuclide techniques are also used to monitor the effect of therapy directed at the HIV itself or against opportunistic infections. This review covers aspects of infection control as well as the use of radionuclides to investigate specific problems related to HIV infection and therapy of the associated disease processes. (author)

  14. Nuclear medicine in psychiatry

    International Nuclear Information System (INIS)

    In the same way that the symptoms between different diseases in psychiatry overlap, functional brain research frequently shows the same pattern of changes across diagnostic borders; on the other hand, many the other tests, e.g. psychological tests, present the same problem as mentioned above; therefore: The psychiatrist seldom applies to an NM specialist to obtain a diagnosis; instead, a nuclear medicine report will rather confirm, or less frequently exclude, the psychiatrist's diagnosis. Ideally, psychiatric patients should be rescanned after the treatment, and changes in perfusion and/or metabolism discussed between psychiatrist and NM specialist. As shown above, there are few practical applications of nuclear medicine due to low specificity and low spatial resolution, although in the aspect of functional imaging it is still superior to CT/MRI, even in their functional modalities. On the other hand, its investigational potential is still growing, as there is no imaging technique in sight which could replace metabolic and receptor studies, and also because the scope of functional imaging in psychiatric diseases is spreading from its traditional applications, like dementia or depression, towards many poorly investigated fields e.g. hypnosis, suicidal behaviour or sleep disorders. (author)

  15. White paper of nuclear medicine

    International Nuclear Information System (INIS)

    This document aims at proposing a synthetic presentation of nuclear medicine in France (definition, strengths and weaknesses, key figures about practices and the profession, stakes for years to come), a description of the corresponding education (speciality definition, abilities and responsibilities, diploma content, proposition by the European Society of Radiology and by the CNIPI, demography of the profession), and an overview of characteristics of nuclear medicine (radio-pharmacy, medical physics, paramedical personnel in nuclear medicine, hybrid imagery, therapy, relationships with industries of nuclear medicine, relationships with health authorities)

  16. Neuroimaging, nuclear medicine

    International Nuclear Information System (INIS)

    This chapter describes radionuclide imaging as it related to neurodegenerative dementias like Alzheimer's disease (AD), idiopathic Parkinson's disease (PD), and normal aging, among the various diseases of the elderly. The role of neuroimaging with nuclear medicine is to detect changes in neural activities that are caused by these diseases. Such changes may be indirect phenomena, but the imaging of neural functions provides physicians with useful, objective information regarding pathophysiology in the brain. Brain activities change with age, with the elderly showing decreased brain function in memory, execution, and attention. Age-dependent reduction in the global mean of cerebral blood flow (CBF) has been reported in many studies that have used X-133 and O-15 labeled gas, the spatial resolution of which is low. Partial volume correction (PVC) is available through the segmentation of grey matter from high-resolution T1-weighted magnetic resonance imaging. Meltzer reported that age-related change disappeared after PVC. The relative distribution of CBF and glucose metabolism has been examined on a voxel-by-voxel basis in many studies. The areas negatively correlated with age are the anterior part of the brain, especially the dorsolateral and medial frontal areas, anterior cingulate cortices, frontolateral and perisylvian cortices, and basal ganglia. The areas positively correlated with age are the occipital lobe, temporal lobe, sensorimotor cortex, and primary visual cortex. It is not easy to define ''normal aging''. Aged people tend to have the potential for diseases like cerebral ischemia caused by arteriosclerosis. Ischemia results in volume loss of the gray matter and CBF. The ApoE e4 gene is a risk factor for AD, and carriers of the ApoE e4 allel show CBF-like AD even at a relatively young age. Hypo-glucose metabolism in the posterior cingulate cortex is seen in 5% of normal people over 50 years of age. This Alzheimer-like CBF/metabolic pattern needs further

  17. Infection diagnosis in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Martin-Comin, J. [Hospital Princeps d`Espanya, Barcelona (Spain). Servicio de Medicina Nuclear

    1997-12-31

    Full text. The clinical applicability of agents like 67 Ga and 111 In-labelled leukocytes began the era of infection imaging diagnosis in Nuclear Medicine, more than two decades ago. In this period other agents have appeared in the field. 99 m Tc-HMPAQ-leukocytes and 99 m Tc-anti granulocyte monoclonal antibodies (able to label white blood cells) and 111 In and 99 mTc-polyclonal immuno globulins (in cold kit presentation). These agents had widespread the use of Nuclear Medicine procedures in clinical practice. Nevertheless, there is not, up to now, an specific agent to diagnose infection and is some cases a second or third agent (i.e.: 99 mTc-colloid) is used to obtain an accurate diagnosis. Actually, research is orientated to the development of agents with low antigenic power (peptides or fragments of monoclonal antibodies), or other non immunogenic agents involved in the inflammation process (selectin, antibiotic). Some experiences have also been done with PET agents. The clinical usefulness of commercially available agents and the future possibilities of the new ones will be presented

  18. Nuclear Medicine Scans for Cancer

    Science.gov (United States)

    ... My ACS » Your Local Offices Close + - Text Size Nuclear Medicine Scans for Cancer Other names for these ... inflammation, or cancer. Use of monoclonal antibodies in nuclear scans A special type of antibody made in ...

  19. Nuclear power in human medicine

    International Nuclear Information System (INIS)

    The public widely associate nuclear power with the megawatt dimensions of nuclear power plants in which nuclear power is released and used for electricity production. While this use of nuclear power for electricity generation is rejected by part of the population adopting the polemic attitude of ''opting out of nuclear,'' the application of nuclear power in medicine is generally accepted. The appreciative, positive term used in this case is nuclear medicine. Both areas, nuclear medicine and environmentally friendly nuclear electricity production, can be traced back to one common origin, i.e. the ''Atoms for Peace'' speech by U.S. President Eisenhower to the U.N. Plenary Assembly on December 8, 1953. The methods of examination and treatment in nuclear medicine are illustrated in a few examples from the perspective of a nuclear engineer. Nuclear medicine is a medical discipline dealing with the use of radionuclides in humans for medical purposes. This is based on 2 principles, namely that the human organism is unable to distinguish among different isotopes in metabolic processes, and the radioactive substances are employed in amounts so small that metabolic processes will not be influenced. As in classical medicine, the application of these principles serves two complementary purposes: diagnosis and therapy. (orig.)

  20. Nuclear medicine and radiopharmacy

    International Nuclear Information System (INIS)

    In the areas of Nuclear Medicine and Radiopharmacy frequently happens that the personnel that is incorporated as a candidate to serve as personnel occupationally exposed have varied skills, not necessarily have an ingrained culture of safety and radiation protection, some are resistant to adoption a work discipline and have very limited notions of normalization, including the safety basic standards. In fact, referring to the safety basic standards, concepts such as practice justification, protection optimization and dose limitation, can be very abstract concepts for such personnel. In regard to training strategies, it was noted that training in the work is an effective tool although it is very demanding for the learner but mainly for the teaches. The experts number that can occur in this manner is limited because it is an individualized system; however those from the process usually acquire a good preparation, which certainly includes theoretical aspects. For greater efficiency it is necessary that hospitals account facilities, procedures and personnel that might have an exclusive dedication to education and training of human resources. This would create a safety culture, alleviating the burdens of the already existing expertise and improves the training conditions. The Mexican Society of Radiological Safety (SMSR) can help in these efforts through the publication of guides aimed at work training, coordination and articulation of the possible courses already on the market and own the courses organization, workshops and conferences with more frequency. It would also serves that the SMSR acts as speaker with political actors, advocating for the courses validation offered by higher learning institutions, coordinating and promoting postgraduates in Nuclear Medicine and Radiopharmacy. (Author)

  1. Calibration measurements of the clinical whole-body counter in the Department of Nuclear Medicine of the General Hospital Vienna

    International Nuclear Information System (INIS)

    Whole-body counters are devices for the measuring and spectroscopy of small amounts of gamma emitting radionuclides in the human body. The Department of Nuclear Medicine of the General Hospital Vienna has such a device (clinical whole-body counter). It represents the type of a shadow shield whole-body counter with a scanning system. The patient is placed on a bed and is moved between four 6'' x 4'' NaI(Tl) detectors with adjustable slit collimators. The whole-body counter was calibrated with regard to channel number, full width at half maximum (FWHM) and efficiency in dependence of the gamma energy of some gamma reference sources. The measurements were performed using a human shaped 70 kg phantom made from water filled plastic bottles, which simulate the absorption and scattering of gamma rays in the human body. Results of the calibration measurements and characteristic quantities like ''minimum detectable activity'' (MDA) and ''minimum measureable activity'' (MMA) will be presented in dependence of the gamma energy. (orig.)

  2. How well does journal 'impact' work in the assessment of papers on clinical physiology and nuclear medicine?

    DEFF Research Database (Denmark)

    Hansen, HB; Henriksen, Jens Henrik Sahl

    1997-01-01

    a particular journal in the year of publication and the subsequent year). The average impact factor per paper was 1.96 and per journal 1.92 (range 0.0-22.8). A direct relation was found between the journal impact factor and the citation factor (i.e. the actual citations in the year of publication...... and the subsequent year) (journals with five or more papers R = 0.69, P < 0.01; all journals R = 0.40, P < 0.001). However, the citation factor was significantly below the journal impact factor (P < 0.0001). An almost linear relation was found between cumulated citations and time (R = 0.99, P < 0......This study reports a citation analysis of 217 scientific papers on clinical physiology and nuclear medicine published in 69 different journals during the years 1985-92. The actual citation frequency was compared with the journal 'impact factor' (i.e. the average number of times a paper is cited in...

  3. Asian School of Nuclear Medicine

    International Nuclear Information System (INIS)

    A number of organisations are involved in the field of nuclear medicine education. These include International Atomic Energy Agency (IAEA), World Federation of Nuclear Medicine and Biology (WFNMB), Asia-Oceania Federation of Nuclear Medicine and Biology (AOFNMB), Society of Nuclear Medicine (SNM in USA), European Association of Nuclear Medicine (EANM). Some Universities also have M.Sc courses in Nuclear Medicine. In the Asian Region, an Asian Regional Cooperative Council for Nuclear Medicine (ARCCNM) was formed in 2000, initiated by China, Japan and Korea, with the main aim of fostering the spread of Nuclear Medicine in Asia. The Asian School of Nuclear Medicine (ASNM) was formed in February 2003, with the ARCCNM as the parent body. The Aims of ASNM are: to foster Education in Nuclear Medicine among the Asian countries, particularly the less developed regions; to promote training of Nuclear Medicine Physicians in cooperation with government agencies, IAEA and universities and societies; to assist in national and regional training courses, award continuing medical education (CME) points and provide regional experts for advanced educational programmes; and to work towards awarding of diplomas or degrees in association with recognised universities by distance learning and practical attachments, with examinations. There are 10 to 12 teaching faculty members from each country comprising of physicists, radio pharmacists as well as nuclear medicine physicians. From this list of potential teaching experts, the Vice-Deans and Dean of ASNM would then decide on the 2 appropriate teaching faculty member for a given assignment or a course in a specific country. The educational scheme could be in conjunction with the ARCCNM or with the local participating countries and their nuclear medicine organisations, or it could be a one-off training course in a given country. This teaching faculty is purely voluntary with no major expenses paid by the ASNM; a token contribution could be

  4. Essentials of nuclear medicine imaging

    CERN Document Server

    Mettler, Fred A. Jr

    2012-01-01

    Essentials of Nuclear Medicine Imaging, by Drs. Fred A Mettler and Milton J Guiberteau, provides the practical and comprehensive guidance you need to master key nuclear imaging techniques. From physics, instrumentation, quality control, and legal requirements to hot topics such as sodium fluoride, radiopharmaceuticals, and recommended pediatric administered doses and guidelines, this sixth edition covers the fundamentals and recent developments in the practice of nuclear medicine.

  5. Nuclear Medicine in Surgical Oncology

    International Nuclear Information System (INIS)

    Defines nuclear medicine as a branch that utilizes nuclear technology for diagnosis and treatment of diseases.The principles of nuclear medicine are; it uses the principle that a certain radiopharmaceutical (tracer) will at a certain point in time have a preferential uptake by a particular body or tissue. it is imaged by use the use of detectors mounted in gamma cameras or PET (Position emission tomography) devices

  6. Quality Management in Nuclear Medicine

    International Nuclear Information System (INIS)

    The IAEA has strong Nuclear medicine (NM) programs and the international basic safety standards require that radiation medicine centers establish a comprehensive quality assurance program for medical exposures supported by internal and external audits. Vital for this is the development of all-inclusive IAEA guideline on 'Quality management in Nuclear Medicine' (also referred to as 'QUANUM'). This document consists of 50 pages and each chapter is set out as a series of questions related to a specific component of NM service. It takes into account the diversity of NM practices and the multidisciplinary contributions (i.e. clinical, physics, radiopharmacy). Self appraisal, external audit and continuous improvement are central elements to improving QA in NM practice. The foremost intention of this document is to introduce a culture of annual systematic review processes into the clinical arena. External audit starts with a formal request together with a completed self appraisal. Each IAEA region will have a pool of trained auditors from each NM discipline. The auditing team will be fully aware of the background and practices by interrogation of NUMDAB (NM database) and recent self appraisal. Normally a 3 day external audit starts with a briefing meeting and ends with a debriefing on the finalization of the audit report. During the external audit, a standardized approach is followed which includes service orientation, introduction to key individuals and access to essential data. The audit team will follow representative clinical cases from clinical requests, clinical direction, patient preparation, radiopharmaceutical dispensing, individual scanning, data processing, report and follow-up of the report. In a few cases, discussions with individual referring physicians will establish patient outcome together with the impact of the NM service. The standards of practice will be compared to national, regional or international guidelines (i.e. IAEA Nuclear medicine resources

  7. Maladministrations in nuclear medicine

    International Nuclear Information System (INIS)

    Maladministration has been defined as the mistaken administration of a radiopharmaceutical to a patient. Examples include the administration of the wrong radiopharmaceutical or the wrong activity to the correct patient or the administration of the correct radiopharmaceutical to the wrong patient. Although maladministrations are rare, lessons can be learnt from the incidents that do occur. Medical maladministrations and other radiation incidents are discussed by members of the NSW Hospital and University Radiation Safety Officers Group (HURSOG) at their bi-monthly meetings. During the three years of 1997-1999 fourteen incidents of maladministrations in nuclear medicine were reported. Analysis of these reports indicated that eight (57 %) were due to the wrong radiopharmaceutical having been administered. This usually occurred because the technologist had selected the wrong lyophilised agent when the radiopharmaceutical was being prepared, or selected the wrong vial of the reconstituted agent. For example, in one instance a vial of MAG3 was reconstituted instead of a vial of HMPAO. These mistakes occurred even though the vials were clearly labelled and sometimes had different coloured labels. Of the remaining 6 cases, two involved the wrong activity being administered due to a mis-read dose calibrator, two involved the wrong procedure being performed following a breakdown in communication and the final two incidents resulted in the wrong patient being administered the radiopharmaceutical. In order to minimise the possibility of recurrence of these incidents the NSW Radiation Advisory Council asked the NSW Branch of the Australian and New Zealand Society of Nuclear Medicine and HURSOG to jointly convene a Working Party to prepare Guidelines for the administration of radiopharmaceuticals. The Guidelines specify: 1. the procedure for the validation of the requested investigation on the request form 2. who should reconstitute, dispense and administer radiopharmaceuticals

  8. Complementary alternative medicine and nuclear medicine

    International Nuclear Information System (INIS)

    Complementary alternative medicines (CAMs), including food supplements, are taken widely by patients, especially those with cancer. Others take CAMs hoping to improve fitness or prevent disease. Physicians (and patients) may not be aware of the potential side-effects and interactions of CAMs with conventional treatment. Likewise, their known physiological effects could interfere with radiopharmaceutical kinetics, producing abnormal treatment responses and diagnostic results. Nuclear medicine physicians are encouraged to question patients on their intake of CAMs when taking their history prior to radionuclide therapy or diagnosis. The potential effect of CAMs should be considered when unexpected therapeutic or diagnostic results are found. (orig.)

  9. What the future holds for nuclear medicine

    International Nuclear Information System (INIS)

    The American College of Nuclear Physicians is primarily interested in the practice aspects of the delivery of nuclear medicine patient care. Yet no specialty in medicine is as directly tied to its scientific base as we are. This International Symposium on Single-Photon Ultrashort-Lived Radionuclides is a classic example of this interdependence. The survival of nuclear medicine as a medical specialty is absolutely dependent on the development of high technology, and the transfer of that technology to medical practice, through the cooperative efforts of industry, government, practitioners, and the research community. If there is no nuclear practice, there will be little outlet for our scientific accomplishments. The American College of Nuclear Physicians therefore considers it to be one of its prime missions to highlight those areas on the leading edge of technology which are, or at least appear to be, ready to bring on-line routine clinical practice

  10. Nuclear medicine in oncology

    International Nuclear Information System (INIS)

    Cancer is increasingly prevalent in our society. There is a life-time risk that 1 in 3 Australian men and 1 in 4 Australian women will get cancer before the age of 75 years. Overall, 27% of the deaths in NSW are currently related to cancer. The common cancers for men are prostate, lung, melanoma, colon, rectum and bladder. For women the common cancers are breast, colon, melanoma, lung and unknown primary. However, overall lung cancer remains the major cause of cancer deaths (20%) followed by colorectal (13%), unknown site (8%), breast and prostate. Breast and lung cancer are the major causes of death in women. Recent information on 5 year survivals reveal good 5 year survival rates for breast (78.6%), prostate (72.4%) and melanoma (92%), while some tumours such as lung cancer (10.7%) have poor survival. Colon cancer has intermediate survival (57.1%). Projections for cancer incidence suggests rates of cancer will increase for colorectal cancer, melanoma, lung cancer in females but decrease for breast, lung in males and prostate cancer. Major strategic directions in cancer research are understanding carcinogenesis, identification of high risk groups, screening and early detection, chemo-prevention, new cancer therapies, combined modality therapy and quality of life issues. Nuclear medicine will play an important part in many of these areas

  11. Future of nuclear medicine

    International Nuclear Information System (INIS)

    When it comes to setting up nuclear medicine in a developing country, there is a group of people, who feel that such high technology has no place in a developing country. RIA is likely to remain the method of choice for the research laboratory. The use of radioisotopic label has many advantages compared to the use of an enzyme marker. Generally, iodination is simpler than the preparation of an enzyme labelled substance, especially since there has been no agreement as to which enzyme is best for substances as small as steroids or a large as viruses. In addition, there may be some change in the configuration of the enzyme or the substance to be labelled during the conjugation procedure. Monoclonal antibodies can provide virtually unlimited amounts of homogenous antibodies against a specific antigenic site. The heterogeneous antibodies are more likely to provide more sensitive assays than the monoclonal antibodies, although assays employing the latter are likely to be more specific. The optimal choice of the antiserum may depend on whether sensitivity or specificity is required for the assays

  12. Scientific publications from departments of clinical physiology and nuclear medicine in Denmark. A bibliometric analysis of "impact' in the years 1989-1994

    DEFF Research Database (Denmark)

    Hansen, H B; Brinch, K; Henriksen, Jens Henrik

    1996-01-01

    This study reports a bibliometric analysis of scientific publications emanating from departments of clinical physiology and nuclear medicine, Denmark, during the years 1989-1994. The total number of publications during this period was 860 (763 scientific journal papers, 71 book/book chapters and 26...... theses). Whereas the number of publications per year (188-113) decreased significantly with time (r = -0.94, P < 0.02), the number of authors (mean 4.1) was almost constant over time. University/ university-related departments accounted for 96% of the papers. Only 8% of the papers resulted from a...... collaboration between two or more departments of clinical physiology and nuclear medicine, but the collaboration with other medical specialities and institutions was much greater (85%). The 763 papers were published in 239 different scientific journals, 80% in journals with an official 'impact factor', a...

  13. The development of nuclear medicine in Slovenia and Ljubljana; half a century of nuclear medicine in Slovenia:

    OpenAIRE

    Gaberšček, Simona; Zupanič Slavec, Zvonka; Slavec, Ksenija

    2012-01-01

    Background Nuclear medicine began to be developed in the USA after 1938 when radionuclides were introduced into medicine and in Europe after radionuclides began to be produced at the Harwell reactor (England, 1947). Slovenia began its first investigations in the 1950s. This article describes the development of nuclear medicine in Slovenia and Ljubljana. The first nuclear medicine interventions were performed in Slovenia at the Internal Clinic in Ljubljana in the period 1954–1959. In 1954, Dr ...

  14. Therapeutic nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Baum, Richard P. (ed.) [ENETS Center of Excellence, Bad Berka (Germany). THERANOSTICS Center for Molecular Radiotherapy and Molecular Imaging

    2014-07-01

    Discusses all aspects of radionuclide therapy, including basic principles, newly available treatments, regulatory requirements, and future trends. Provides the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Explains the role of the therapeutic nuclear physician in effectively coordinating a diverse multidisciplinary team. Written by leading experts. The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. The selective irradiation of tumor cells through molecular biological mechanisms is now permitting the radiopharmaceutical control of tumors that are unresectable and unresponsive to either chemotherapy or conventional radiotherapy. In this up-to-date, comprehensive book, world-renowned experts discuss the basic principles of radionuclide therapy, explore in detail the available treatments, explain the regulatory requirements, and examine likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the important role of the therapeutic nuclear physician in delivering the effective coordination of a diverse multidisciplinary team that is essential to the safe provision of treatment.

  15. Therapeutic nuclear medicine

    International Nuclear Information System (INIS)

    Discusses all aspects of radionuclide therapy, including basic principles, newly available treatments, regulatory requirements, and future trends. Provides the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Explains the role of the therapeutic nuclear physician in effectively coordinating a diverse multidisciplinary team. Written by leading experts. The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. The selective irradiation of tumor cells through molecular biological mechanisms is now permitting the radiopharmaceutical control of tumors that are unresectable and unresponsive to either chemotherapy or conventional radiotherapy. In this up-to-date, comprehensive book, world-renowned experts discuss the basic principles of radionuclide therapy, explore in detail the available treatments, explain the regulatory requirements, and examine likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the important role of the therapeutic nuclear physician in delivering the effective coordination of a diverse multidisciplinary team that is essential to the safe provision of treatment.

  16. The state of the art in diagnostic nuclear medicine

    International Nuclear Information System (INIS)

    Recent improvements in the understanding of the physiologic and biologic mechanisms of health and disease have led to an expansion of nuclear medicine applications both in clinical studies and research. Advances in radiopharmaceutical development, instrumentation and computer processing have resulted in the implementation of Positron Emission Tomography for clinical studies, and improved treatments with radiopharmaceuticals particularly in cancer patients. There has also been an dramatic increase in the techniques available with nuclear medicine to detect and measure cellular biologic events in-vivo, which have important implications in clinical and basic science research. Nuclear medicine studies provide unique information on human physiology and remain an integral part of clinical medicine practice

  17. The state of the art in nuclear medicine

    International Nuclear Information System (INIS)

    Recent improvements in the understanding of the physiologic and biologic mechanisms of health and disease have led to an expansion of nuclear medicine applications both in clinical studies and research. Advances in radiopharmaceutical development, instrumentation and computer processing have resulted in the implementation of Positron Emission Tomography for clinical studies, and improved treatments with radiopharmaceuticals particularly in cancer patients. There has also been a dramatic increase in the techniques available with nuclear medicine to detect and measure cellular biologic events in-vivo, which have important implications in clinical and basic science research. Nuclear medicine studies provide unique information on human physiology and remain an integral part of clinical medicine practice

  18. Applications of nuclear medicine in genitourinary imaging

    Energy Technology Data Exchange (ETDEWEB)

    Blaufox, M.D.; Kalika, V.; Scharf, S.; Milstein, D.

    1982-01-01

    Major advances in nuclear medicine instrumentation and radiopharmaceuticals for renal studies have occurred during the last decade. Current nuclear medicine methodology can be applied for accurate evaluation of renal function and for renal imaging in a wide variety of clinical situations. Total renal function can be estimated from the plasma clearance of agents excreted by glomerular filtration or tubular secretion, and individual function can be estimated by imaging combined with renography. A major area of radionuclide application is in the evaluation of obstructive uropathy. The introduction of diuretic renography and the use of computer-generated regions of interest offer the clinician added useful data which may aid in diagnosis and management. Imaging is of proven value also in trauma, renovascular hypertension, and acute and chronic renal failure. Methods for the evaluation of residual urine, vesicoureteral reflux, and testicular torsion have achieved increasing clinical use. These many procedures assure a meaningful and useful role for the application of nuclear medicine in genitourinary imaging.

  19. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Pediatric Ultrasound Video: Angioplasty & vascular stenting Video: Arthrography Radiology and You About this Site RadiologyInfo.org is ... Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! I’m Dr. Ramji ...

  20. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... before abnormalities can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – called radiotracers – that are typically injected into the ...

  1. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Angioplasty & vascular stenting Video: Arthrography Video: Contrast Material Radiology and You Take our survey About this Site ... Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! I’m Dr. Ramji ...

  2. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... relatively low and the benefit of an accurate diagnosis far outweighs any risk. To learn more about nuclear medicine, visit Radiology Info dot org. Thank you for your time! ...

  3. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... If you’re scheduled for a nuclear medicine exam, there are several things you can do to ... to refrain from taking certain medications before the exam. Also, it’s best to leave any jewelry at ...

  4. Development of nuclear medicine in Mongolia

    International Nuclear Information System (INIS)

    , equipment, space and work load. The department replaced its old Siemens gamma camera with a GE gamma camera in the year 1996, and upgraded its RIA laboratory in the year 1999. In tandem with developments in the field of nuclear medicine, the department acquired its first SPECT Elscint camera in 2000, a single detector device with 40-cm field of view. That year, we introduced for the first time Nuclear Cardiology procedures in Mongolia including Myocardial Perfusion Imaging. To-day, the nuclear medicine department of The First State Central Clinic Hospital is a vibrant set-up offering a spectrum of diagnostic and therapeutic procedures to the people of Mongolia. The current staff strength consists of 4 medical doctors, 1 medical physicist, 1 radiopharmacist, 5 technologists and 2 laboratory assistants. During the past 25 years the department has conducted Radionuclide investigations on more than 80,000 patients. The number of nuclear medicine procedures and investigations have been increasing every year. During 2000 the department had conducted more than 4000 diagnostic nuclear medicine procedures. With regard to Radionuclide therapy, the department has been engaged in the radioiodine treatment of thyrotoxicosis since 1982. The departmental activities in the field of therapeutic nuclear medicine took a big leap forward this year, when it introduced the Radionuclide treatment of Liver Cancer using Re-188 Lipiodol in March, 2002. IAEA's contribution to the growth and development of nuclear medicine in Mongolia has been of immense value. The country in general and the department in particular has benefited significantly from IAEA support through its several technical cooperation and coordinated research projects. Such support has provided opportunities to Mongolia in enhancing its human resources in the field of nuclear medicine, upgrading equipment, introducing new technologies and providing the state of the art medical care to its people using nuclear medicine technology

  5. Radiation protection in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Mattsson, Soeren [Lund Univ., Skane Univ. Hospital Malmoe (Sweden). Medical Radiation Physics; Hoeschen, Christoph (eds.) [Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt GmbH, Neuherberg (Germany)

    2013-07-01

    Addresses all aspects of radiation protection in nuclear medicine. Covers current technologies and principles. An ideal textbook for students and a ready source of information for nuclear medicine specialists and medical physics experts. One of a series of three books on the fundamentals of modern nuclear medicine (physics, safety, and imaging). This book explains clearly and in detail all aspects of radiation protection in nuclear medicine. After an introductory chapter on the general role of radiation protection, measurement quantities and units are discussed, and detectors and dosimeters, described. Radiation biology and radiation dosimetry are then addressed, with the inclusion of a chapter specifically devoted to biology and dosimetry for the lens of the eye. Discussion of radiation doses to patients and to embryos, fetuses, and children forms a central part of the book. Phantom models, biokinetic models, calculations, and software solutions are all considered, and a further chapter focuses on quality assurance and reference levels. Occupational exposure also receives detailed attention. Exposure resulting from the production, labeling, and injection of radiopharmaceuticals and from contact with patients is discussed and shielding calculations are explained. The book closes by considering exposure of the public and summarizing the ''rules of thumb'' for radiation protection in nuclear medicine. This is an ideal textbook for students and a ready source of useful information for nuclear medicine specialists and medical physics experts.

  6. Nuclear medicine - from physiology to molecular imaging

    International Nuclear Information System (INIS)

    The induction of Medical Imaging in clinical practice occurred through Nuclear Medicine in 1937 through the first application of 131-Iodine in tracer imaging. The concept translated rapidly into other areas of clinical medicine through the invention of newer radiopharmaceuticals over the next six decades. The growth of nuclear imaging acted as a catalyst for other imaging modalities like sonography, CT scan and MRI. In effect everywhere nuclear medicine was the stimulus and growth has taken place around its concepts. This in turn strengthened and stimulated further fascinating developments in nuclear medicine so much that today it is the fascinating era of 'FUSION IMAGING' in medical diagnosis. The CT and MRI succeeded in producing exquisite images of human organs with details as close to as a pathologist would see in histology room after the organ is delivered to him. Unfortunately the pathophysiological details of the disease how, why, when etc - remained unanswered. Hence the impact on treatment was not drastic as modulation of disease process is possible only if we know how and why and when it occurred. These searching questions continued to stimulate the research in nuclear medicine and outcome has been tremendous in the last few years

  7. Clinical nuclear medicine

    International Nuclear Information System (INIS)

    Progress is reported in the following areas of research: radionuclide lung-imaging procedures in the assessment of injury due to ammonia and carbon monoxide inhalation and chronic obstructive pulmonary disease; physiological diagnosis of pulmonary embolism; dynamic imaging of the dual circulation of lung cancer; and an intravenous radionuclide method to evaluate hyposemia caused by abnormal alveolar vessels

  8. Quality management audits in nuclear medicine practices

    International Nuclear Information System (INIS)

    An effective management system that integrates quality management (QM) is essential in modern nuclear medicine departments in Member States. The IAEA, in its Safety Standards Series, has published a Safety Requirement (GS-R-3) and a Safety Guide (GS-G-3.1) on management systems for all facilities. These publications address the application of an integrated management system approach that is applicable to nuclear medicine organizations as well. Quality management systems are maintained with the intent to continuously improve effectiveness and efficiency, enabling nuclear medicine to achieve the expectations of its quality policy, and to satisfy its customers. The IAEA has a long history of providing assistance in the field of nuclear medicine to its Member States. Regular quality audits and assessments are essential for modern nuclear medicine departments. More importantly, the entire QM and audit process has to be systematic, patient oriented and outcome based. The management of services should also take into account the diversity of nuclear medicine services around the world and multidisciplinary contributions. The latter include clinical, technical, radiopharmaceutical and medical physics procedures. Aspects of radiation safety and patient protection should also be integral to the process. Such an approach ensures consistency in providing safe, quality and superior services to patients. Increasingly standardized clinical protocol and evidence based medicine is used in nuclear medicine services, and some of these are recommended in numerous IAEA publications, for example, the Nuclear Medicine Resources Manual. Reference should also be made to other IAEA publications such as the IAEA Safety Standards Series, which include the regulations for the safe transport of nuclear material and on waste management as all of these have an impact on the provision of nuclear medicine services. The main objective of this publication is to introduce a routine of conducting an

  9. Review: radioprotection applied in Nuclear Medicine

    International Nuclear Information System (INIS)

    The aim of this paper is to evaluate the potential causes of exposure to ionizing radiation in a nuclear medicine facility, identifying the causes of common errors in the clinical routine, how to avoid these errors and study good radioprotection practices based on the national law and international documents. (author)

  10. Nuclear medicine and thyroid disease - part II

    International Nuclear Information System (INIS)

    Part 1 of this article discussed the anatomy, physiology and basic pathology of the thyroid gland. Techniques of thyroid scanning and a few clinical examples are shown part II Copyright (2005) The Australian and New Zealand Society Of Nuclear Medicine Inc

  11. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... medicine will interpret the images and forward a report to your referring physician. top of page What ... by: Please note RadiologyInfo.org is not a medical facility. Please contact your physician with specific medical ...

  12. Annual congress of the European Association of Nuclear Medicine. EANM'14. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-10-15

    The proceedings of the annual congress of the European Association of Nuclear Medicine EANM'14 contain abstracts on the following issues: nuclear cardiology practices, PET in lymphoma, advances in nuclear cardiology, dosimetry for intra-arterial treatment in the liver, pediatric nuclear medicine, therapeutic nuclear medicine, SPECT/CT, prostate cancer, extended competencies for nuclear medicine technologists, neurosciences - neurodegeneration and neuroinflammation, radionuclide therapy and dosimetry - preclinical studies, physics and instrumentation, clinical molecular imaging, conventional and specialized nuclear medicine.

  13. European Association of Nuclear Medicine congress. Abstracts

    International Nuclear Information System (INIS)

    To assess the exact place of nuclear medicine studies in the clinical environment in consensus with clinicians and radiologists will probably be our most important task during the coming year. Our society cannot afford unnecessary duplication of diagnostic tests but neither should our patients suffer from the failure to use procedures which could change the outcome of their illness or avoid unnecessary pain and costs because of ignorance, or even worse, self defence by larger and thus stronger pressure groups. Defeatism is as inappropriate as remaining in the splendid isolation of our professional and scientific organisations. There is no place for excessive humbleness either, most of the unnecessary procedures performed in modern medicine lie within the domain of other specialists. It is our duty to participate as actors in the thorough reappraisal of the medical, social and economic context of our activity in the interst of our field and our patients. By confronting our ideas and knowledge with those of others, by using our inventiveness to transfer important results from research laboratories to clinical practice and vice versa, by concentrating on the essential rather than pursuing all possible directions, we will be able to influence positively the future of nuclear medicine. There is no better way to develop our speciality than by understanding the clinical issues, by being able to communicate with our clinical partners and by performing common studies on the clinical impact, cost-efficiency and cost-benefit of nuclear medicine procedures. (orig./AJ)

  14. The role of general nuclear medicine in breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Greene, Lacey R, E-mail: lgreene@csu.edu.au [Faculty of Science, Charles Sturt University, Wagga Wagga, New South Wales (Australia); Wilkinson, Deborah [Faculty of Health, Wheeling Jesuit University, Wheeling, West Virginia (United States); Faculty of Science, Charles Sturt University, Wagga Wagga, New South Wales (Australia)

    2015-03-15

    The rising incidence of breast cancer worldwide has prompted many improvements to current care. Routine nuclear medicine is a major contributor to a full gamut of clinical studies such as early lesion detection and stratification; guiding, monitoring, and predicting response to therapy; and monitoring progression, recurrence or metastases. Developments in instrumentation such as the high-resolution dedicated breast device coupled with the diagnostic versatility of conventional cameras have reinserted nuclear medicine as a valuable tool in the broader clinical setting. This review outlines the role of general nuclear medicine, concluding that targeted radiopharmaceuticals and versatile instrumentation position nuclear medicine as a powerful modality for patients with breast cancer.

  15. The role of general nuclear medicine in breast cancer

    International Nuclear Information System (INIS)

    The rising incidence of breast cancer worldwide has prompted many improvements to current care. Routine nuclear medicine is a major contributor to a full gamut of clinical studies such as early lesion detection and stratification; guiding, monitoring, and predicting response to therapy; and monitoring progression, recurrence or metastases. Developments in instrumentation such as the high-resolution dedicated breast device coupled with the diagnostic versatility of conventional cameras have reinserted nuclear medicine as a valuable tool in the broader clinical setting. This review outlines the role of general nuclear medicine, concluding that targeted radiopharmaceuticals and versatile instrumentation position nuclear medicine as a powerful modality for patients with breast cancer

  16. Nuclear Medicine Imaging

    Science.gov (United States)

    ... necesita saber acerca de... Estudios de Imagen de Medicina Nuclear Un procedimiento de medicina nuclear se describe algunas veces como unos rayos- ... través del cuerpo del paciente. Los procedimientos de medicina nuclear utilizan pequeñas cantidades de mate- riales radiactivos, ...

  17. Nuclear medicine quality assurance program in Argentina

    International Nuclear Information System (INIS)

    A two steps program has been implemented: the first one is the quality control of the equipment and the second one the development of standard procedures for clinical studies of patients. A training program for doctors and technicians of the nuclear medicine laboratories was carried out. Workshops on instrumentation and quality assurance in nuclear medicine have been organized in several parts of the country. A joint program of the CNEA and the University of Buenos Aires has trained medical physicists. A method has been established to evaluate the capability of the laboratories to produce high quality images and to follow up the implementation of the quality control program

  18. Clinical Service of Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The clinical practice of traditional Chinese medicine (TCM) faces three major challenges:(1)How to enhance its contribution on overall medical service quality? (2) How to best address the unmet medical needs in the contemporary society? (3)How to guarantee that the traditional perspective for disease diagnosis and treatment not be neglected in clinical practice?

  19. THERAPEUTIC APPLICATIONS IN NUCLEAR MEDICINE

    Directory of Open Access Journals (Sweden)

    Cristofer Alan Costa Santos

    2014-12-01

    Full Text Available Due to poor understanding of the role of nuclear medicine in several disease treatments, the aim of this study was to demonstrate the main therapeutic applications of nuclear medicine as well as their characteristics and radiopharmaceuticals usage through scientific literature review. The main therapeutic applications of nuclear medicine are radio-immunotherapy with iodine-131, yttrium-90, lutetium-177 and copper-67, the radiosynovectomy with yttrium-90, rhenium-186 and gold-198 and pain palliation of osseous metastases with samarium-153, strontium-89 and phosphorus-32. The radioiodine therapy with iodine-131 stands out among therapies because it allows a highly selective treatment of thyroid associated with hyperthyroidism and differentiated thyroid cancer with favorable dosimetry to healthy tissues and with great advantage to allow the ablation of disseminated lesions due to metastases, success not achieved by traditional radiotherapy. Thus, the therapeutic nuclear medicine is an alternative tool, and often essential for definitive treatment of various diseases considered incurable once. Thus, therapeutic nuclear medicine is an alternative and often essential tool for definitive treatment of various diseases considered once incurable.

  20. Status of nuclear medicine in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Lee, M.H. (Seoul National Univ. (Republic of Korea). Coll. of Medicine)

    1982-03-01

    The medical application of nuclear medicine in Korea finds its origin in June, 1959, when radioactive iodine therapy was given to a patient with hyperthyroidism, while the legal background for the medical uses of radioisotopes was provided by the Atomic Energy Law promulgated in 1958. The real active application of radioisotope in clinical medicine, however, was made possible as the Radioisotope Clinic was opened at the Seoul National University Hospital in April, 1960. In the early 1960's four medical institutes had radioisotope facilities including scintiscanners, scintillation counters, detectors and spectrometers some of which were provided by the United States Atomic Energy Commission. And now, radioisotopes were applied in 45 medical institutes. At the beginning, thyroid function tests and ferrokinetic studies were primary clinical applications. Scanning of various organs became generalized with the wide use of the photoscanners from 1964 and scintillation cameras from 1969. A new era in the development of the nuclear medicine has started in March, 1979 with the use of computer system in the dynamic studies including radionuclide cardiac angiography and sequential renal scan. At present 13 gamma cameras and 4 computer systems were used in the field of nuclear medicine. Radioimmunoassay techniques began to be used from 1969 and at present about fifty items of tests are being performed for the research purposes and clinical applications.

  1. Nuclear medicine - no. 3

    International Nuclear Information System (INIS)

    This bulletin contains seven articles relating to the isotopic applications in medicine. Their subject matter ranges from the preparation of radiopharmaceuticals through their application in scintiscanning to computer codes for evaluation of the results. The individual articles have been indexed separately

  2. Radiation physics for nuclear medicine

    CERN Document Server

    Hoeschen, Christoph

    2011-01-01

    The field of nuclear medicine is expanding rapidly, with the development of exciting new diagnostic methods and treatments. This growth is closely associated with significant advances in radiation physics. In this book, acknowledged experts explain the basic principles of radiation physics in relation to nuclear medicine and examine important novel approaches in the field. The first section is devoted to what might be termed the "building blocks" of nuclear medicine, including the mechanisms of interaction between radiation and matter and Monte Carlo codes. In subsequent sections, radiation sources for medical applications, radiopharmaceutical development and production, and radiation detectors are discussed in detail. New frontiers are then explored, including improved algorithms for image reconstruction, biokinetic models, and voxel phantoms for internal dosimetry. Both trainees and experienced practitioners and researchers will find this book to be an invaluable source of up-to-date information.

  3. Nuclear Medicine on the net

    International Nuclear Information System (INIS)

    Full text: To gain insight into Internet usage as a potential means of communicating with clinicians. Method: 200 clinicians within the South Western Sydney Health Area were surveyed by mail. Questionnaire details included Internet access, frequency of access, interest in department web site, suitability of content and interest in electronic bookings. The total response rate was 37% (74/200). General Practitioners comprised 46% of the respondents, and specialists 54%. All respondents had access to the Internet (44% from home only, 8% from work, 48% from both locations), with 57% accessing the Web daily. There was a high overall interest by respondents in accessing a Nuclear medicine web site, particularly for information and results, but a relative reluctance to consider electronic bookings. The following table outlines the respondents in detail. Our results indicate that a Nuclear Medicine web site has the potential to be an effective means of communicating with clinicians. Copyright (2003) The Australian and New Zealand Society of Nuclear Medicine Inc

  4. Radiation protection in nuclear medicine

    International Nuclear Information System (INIS)

    Radiation protection in nuclear medicine in this project is concerned with the reduction of doses to workers, patients and members of the public. Protection of workers is achieved by adopting good personal habits, good housekeeping, proper use of personal protective devices and equipment, attend training and have continuous education. Exposure to radiation of workers and the members of the public are minimised by proper management of radioactive waste and safe transport of radioactive material. The design and shielding of a nuclear medicine department shall further provide for the protection of the worker, the patient and the general public. Protection of patient is achieved by justifying the procedure, delivering the minimum radiation dose possible to the patient while obtaining the best image quality and applying guidance levels. Special considerations shall be given to pregnant and breast-feeding patients. Quality assurance programme through image quality, radiopharmaceutical quality and patient records on nuclear medicine procedures shall provide assurance to the patient. (au)

  5. The contribution of medical physics to nuclear medicine: a physician's perspective

    OpenAIRE

    Peter J. Ell

    2014-01-01

    This paper is the second in a series of invited perspectives by four pioneers of nuclear medicine imaging and physics. A medical physicist and a nuclear medicine clinical specialist each take a backward look and a forward look at the contributions of physics to nuclear medicine. Here is a backward look from a nuclear medicine physician's perspective.

  6. Journal of Clinical Medicine Editorial

    Directory of Open Access Journals (Sweden)

    Jane M. Grant-Kels

    2012-12-01

    Full Text Available “Why yet another journal?” Because this new journal will be different in that we are not just about new information but about understanding new information. We are online, peer reviewed, with a quick turnaround time from submission to publication and without any limit regarding length! Therefore, I am honored to introduce the Journal of Clinical Medicine (JCM, which has been created to serve as a hub for disseminating new findings and discoveries in clinical medicine to clinicians and medical researchers worldwide. [...

  7. A nuclear chocolate box: the periodic table of nuclear medicine.

    Science.gov (United States)

    Blower, Philip J

    2015-03-21

    Radioisotopes of elements from all parts of the periodic table find both clinical and research applications in radionuclide molecular imaging and therapy (nuclear medicine). This article provides an overview of these applications in relation to both the radiological properties of the radionuclides and the chemical properties of the elements, indicating past successes, current applications and future opportunities and challenges for inorganic chemistry. PMID:25406520

  8. Breast cancer. Diagnostic nuclear medicine and radiology

    International Nuclear Information System (INIS)

    The book focuses on the presentation of long established and recently developed nuclear medicine techniques for diagnostic evaluation of carcinoma of the mammary gland and the metastases, primarily scintigraphy and positron emission tomography (PET). The methodological information is enhanced by information on the latest results obtained of the methods not yet applied as techniques of clinical routine. The current techniques of diagnostic radiology are discussed in the framework of a critical review of results and restraints of all diagnostic methods available at present. Special emphasis is placed on elaborating the comparative assessment along the line of the catalogue of clinical, diagnostic objectives or problems and the resulting clinical rating. The material thus gives a comprehensive, up-to-date overview of well-known and recent methods of diagnostic nuclear medicine in comparison to the established radiological imaging methods. (orig./CB)

  9. Pulmonary nuclear medicine

    International Nuclear Information System (INIS)

    This article reviews the contribution made by nuclear imaging to the assessment, diagnosis and monitoring of patients with respiratory disease. It focuses on several specific areas including the diagnosis of pulmonary embolism, the investigation of intrapulmonary infection and neoplasm and the role positron emission tomography (PET) scanning. (orig.)

  10. Management of radioactive waste generated in nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine is a clinical specialty in which radioactive material is used in non-encapsulated form, for the diagnosis and treatment of patients. Nuclear medicine involves administering to a patient a radioactive substance, usually liquid, both diagnostic and therapeutic purposes. This process generates solid radioactive waste (syringes, vials, gloves) and liquid (mainly the patient's urine). (Author)

  11. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... through the area being examined and gives off energy in the form of gamma rays which are detected by a special camera and computer to create images of the inside of your body. If you’re scheduled for a nuclear medicine exam, there are several things you can ...

  12. Scientific publications from departments of clinical physiology and nuclear medicine in Denmark. A bibliometric analysis of "impact' in the years 1989-1994

    DEFF Research Database (Denmark)

    Hansen, HB; Brinch, K; Henriksen, Jens Henrik Sahl

    1996-01-01

    This study reports a bibliometric analysis of scientific publications emanating from departments of clinical physiology and nuclear medicine, Denmark, during the years 1989-1994. The total number of publications during this period was 860 (763 scientific journal papers, 71 book/book chapters and 26...... bibliometric measure of quality (the average number of times a paper is cited in a journal in the publishing year and the subsequent year). Twenty per cent (20%) and 8.4% were printed in journals with an impact factor, respectively, of above 2.1 (the 500 journals most cited) and 3.7 (the 200 most cited), which...

  13. History and Perspectives of Nuclear Medicine in Thailand

    Directory of Open Access Journals (Sweden)

    Sombut Boonyaprapa

    2014-10-01

    Full Text Available In 1955, the first nuclear medicine division was established in Thailand by Professor Romsai Suwannik in the Department of Radiology, Siriraj Hospil, Mahidol University in Bangkok. In 1959 four years later, the second nuclear medicine division was established in the Department of Radiology, Chulalongkorn Hospital in Bangkok. The third nuclear medicine division was started in Rajvithi Hospital in Bangkok in 1961. The fourth nuclear medicine division was installed in Chiang Mai University which is the first University located outside of Bangkok in 1965 by Professor Dusadee Prabhasavat and Professor Sanan Simarak, ten years after the first nuclear medicine division in Siriraj Hospital. At the present in Thailand, there are twenty-five organizations providing clinical nuclear medicine services. Five medical faculties provide three years nuclear medicine residency training. There are eight companies which supply radiopharmaceuticals and/or nuclear medicine instruments one of these belongs to governmental office of atomic for peace (OAP of Thailand. In conclusion: Nuclear medicine researches and clinical practices in Thailand had been progressed from the past to the present time and will more progress in the near future, which certainly is the part of Asian countries and ARCCNM.

  14. Nuclear medicine procedures in lung cancer

    International Nuclear Information System (INIS)

    Although radiography, computed tomography and magnetic resonance imaging are still the methods of choice for the study of lung cancer, they have certain limitations in the determination of the nature of suspicious lung nodules, the evaluation of mediastinal involvement, the assessment of the viability of previously treated lesions and the diagnosis of tumour relapse. There is a wide range of current oncological requirements related to lung cancer: detection of malignant lesions at the earliest stage and in the most effective way; the definition of the biological characteristics of a lesion (proliferation, aggressiveness, differentiation, etc.); the need to define the operability of the patient (function of residual lung and staging); and the need to evaluate the behaviour of the tumour (response to therapy, early detection of recurrences, metastatic spread). Most of the efforts of the nuclear medicine community have been focussed on diagnosis, staging, restaging and therapy monitoring of lung cancer. Many radiopharmaceuticals have been employed for this, including gallium, monoclonal antibodies, somatostatin analogues, lipophilic cations and positron emission tracers. There is ample evidence that nuclear medicine techniques may provide complementary information with respect to anatomical imaging, for example in the assessment of preoperative function by means of ventilation and perfusion scintigraphy, or in tumour localisation by means of specific tumour-seeking agents. However, clinical data suggest that, when properly used, nuclear medicine procedures in some cases may be not only complementary to radiology but essential for the clinical management of lung cancer. An example of such a procedure is fluorodeoxyglucose positron emission tomography (FDG PET) the introduction of which has greatly contributed to confirmation of the clinical value of nuclear medicine in this field. FDG PET has proved of great help in lung cancer management and its cost-effectiveness in

  15. Evolution of nuclear medicine: a historical perspective

    International Nuclear Information System (INIS)

    The field Nuclear Medicine has Completed its 100 yeas in 1996. Nuclear medicine began with physics, expanded into chemistry and instrumentation, and then greatly influenced various fields of medicine. The chronology of the events that formulated the present status of nuclear medicine involves some of the great pioneers of yesterday like Becquerel, Curie, Joliot, Hevesy, Anger, Berson and Yallow. The field of nuclear medicine has been regarded as the bridge builder between various aspects of health care and within next 20 years, nuclear medicine enters a new age of certainty, in which surgery, radiation and chemotherapy will only be used when a benefit in certain to result from the treatment. (author)

  16. A concise guide to nuclear medicine

    CERN Document Server

    Elgazzar, Abdelhamid H

    2011-01-01

    Nuclear medicine is an important component of modern medicine. This easy-to-use book is designed to acquaint readers with the basic principles of nuclear medicine, the instrumentation used, the gamut of procedures available, and the basis for selecting specific diagnostic or therapeutic procedures and interpreting results. After an introductory chapter on the history, technical basis, and scope of nuclear medicine, a series of chapters are devoted to the application of nuclear medicine techniques in the different body systems. In addition, the use of nuclear medicine methods within oncology is

  17. Physics and radiobiology of nuclear medicine

    CERN Document Server

    Saha, Gopal B

    2013-01-01

    The Fourth Edition of Dr. Gopal B. Saha’s Physics and Radiobiology of Nuclear Medicine was prompted by the need to provide up-to-date information to keep pace with the perpetual growth and improvement in the instrumentation and techniques employed in nuclear medicine since the last edition published in 2006. Like previous editions, the book is intended for radiology and nuclear medicine residents to prepare for the American Board of Nuclear Medicine, American Board of Radiology, and American Board of Science in Nuclear Medicine examinations, all of which require a strong physics background. Additionally, the book will serve as a textbook on nuclear medicine physics for nuclear medicine technologists taking the Nuclear Medicine Technology Certification Board examination.

  18. Extracts from IAEA's Resources Manual in Nuclear Medicine. Part-3: Establishing Nuclear Medicine Services

    International Nuclear Information System (INIS)

    In the past, consideration was given to the categories of nuclear medicine ranging from simple imaging or in-vitro laboratories, to more complex departments performing a full range of in-vitro and in-vivo procedures that are also involved in advanced clinical services, training programmes, research and development. In developing countries, nuclear medicine historically has often been an offshoot of pathology, radiology or radiotherapy services. These origins are currently changing as less radioimmunoassay is performed and fully-fledged, independent departments of nuclear medicine are being set up. The trend appears to be that all assays (radioassay or ELISA) are done in a biochemistry laboratory whereas nuclear medicine departments are involved largely in diagnostic procedures, radionuclide therapy and non-imaging in-vitro tests. The level of nuclear medicine services is categorized according to three levels of need: Level 1: Only one gamma camera is needed for imaging purposes. The radiopharmaceutical supply, physics and radiation protection services are contracted outside the centre. Other requirements include a receptionist and general secretarial assistance. A single imaging room connected to a shared reporting room should be sufficient, with a staff of one nuclear medicine physician and one technologist, with back-up. This level is appropriate for a small private practice. Level 2: This is suitable for a general hospital where there are multiple imaging rooms where in-vitro and other non-imaging studies would generally be performed as well as radionuclide therapy. Level 3: his is appropriate for an academic institution where there is a need for a comprehensive clinical nuclear medicine service, human resource development and research programmes. Radionuclide therapy for in-patients and outpatients is provided

  19. Neutron use in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Guidez, J.; May, R.; Moss, R. [HFR-Unit, European Commission, IAM, Petten (Netherlands); Askienazy, S. [Departement Central de Medicine Nucleaire et Biophysique, Saint Antoine Hospital, Paris (France); Hildebrand, J. [Neurology Department, Erasmus Hospital, Brussels (Belgium)

    1999-07-01

    Neutrons produced by research reactors are being used in nuclear medicine and other medical applications in several ways. The High Flux Reactor (HFR) based in Petten (The Netherlands), owned by the European Commission, has been working increasingly in this field of health care for the European citizen. On the basis of this experience, a survey has been carried out on the main possibilities of neutrons used in nuclear medicine. The most important and most well known is the production of radioisotopes for diagnosis and therapy. Ten million patients receive nuclear medicine in Europe each year, with more than 8 million made with the products issued from research reactors. The survey of the market and the techniques (cyclotron, PET) shows that this market will continue to increase in the future. The direct use of reactors in medicine is actually made by the Boron Neutron capture Therapy (BNCT) for the treatment of glioblastoma, which kills about 15.000 people in Europe each year. For this promising technique, HFR is the most advanced for experimental possibilities and treatment studies. Medical research is also made in other promising fields: the use beam tubes for characterizing of prostheses and bio-medical materials, alpha-immuno therapy products, new types of radioisotopes, new types of illness to be treated by BNCT, etc. (author)

  20. Essentials of nuclear medicine physics and instrumentation

    CERN Document Server

    Powsner, Rachel A; Powsner, Edward R

    2013-01-01

    An excellent introduction to the basic concepts of nuclear medicine physics This Third Edition of Essentials of Nuclear Medicine Physics and Instrumentation expands the finely developed illustrated review and introductory guide to nuclear medicine physics and instrumentation. Along with simple, progressive, highly illustrated topics, the authors present nuclear medicine-related physics and engineering concepts clearly and concisely. Included in the text are introductory chapters on relevant atomic structure, methods of radionuclide production, and the interaction of radiation with matter. Fu

  1. Nuclear medicine. 2. rev. and enlarged ed.

    International Nuclear Information System (INIS)

    This second edition of the textbook on nuclear medicine is intended as a comprehensive and explanatory source of current theoretical and practical knowledge required for practical application of nuclear medicine techniques for diagnostics and therapy. The first part of the book deals with general aspects such as physical principles, the labelling and quality control of radiopharmaceuticals, and specific kinetics of some preparations, scanning techniques and the relevant equipment including aspects such as equipment handling, functional monitoring, error sources, patent positioning, as well as radiation protection and the handling of radioactive substances at the place of work. This part also explains the organisational framework of a nuclear medicine practice or department and the professional training and tasks of a radiographer in nuclear medicine. The second part is devoted to specific tasks and techniques for diagnostic assessment of the different body organs, illustrated by examples and summarised in tables given at the end of each chapter. Examples of clinical experience explain the criteria for selection of suitable diagnostic technique. (orig.) With 207 figs., 14 tabs

  2. Nuclear medicine and its radiological protection in China

    International Nuclear Information System (INIS)

    The China Society of Nuclear Medicine was established on 27 May 1980. Since then, nuclear medicine in clinical diagnosis and therapy has been developed rapidly in China. So far there are more than 4000 members of the Society, and more than 350 sets of SPECT and 12 sets of PET have been installed and are busily running in clinic nowadays and about 1 million patients with different types of diseases have obtained nuclear medicine imaging examinations per year. Concerning the nuclear medicine therapy, a lot of patients with many types of diseases obtained benefit from radioisotope therapy. Accordingly, several Policies and Regulations have been enacted by the Government for the radiological protection. Furthermore, a special book titled 'Standardization in Diagnostic and Therapeutic Nuclear Medicine' has been promulgated in June, 1997 by the Health Administration of People's Republic of China, and this book is distributed to almost every nuclear medicine physician and technician in China for their reference in routine nuclear medicine work or research. In this book three parts of the contents are covered: Policies and Regulations for the radiological protection, basic knowledge and clinical nuclear medicine applications. (author)

  3. Distribution of nuclear medicine service in Brazil; Distribuicao do servico de medicina nuclear no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Ana Carolina Costa da; Duarte, Alessandro; Santos, Bianca Maciel dos [Faculdade Metodo de Sao Paulo (FAMESP), Sao Paulo, SP (Brazil)

    2011-10-26

    The Brazil does not posses a good distribution of nuclear medicine service por all his territory. This paper shows the difference among country regions as far the number of clinics of nuclear medicine as is concerning, and also doctors licensed in the area and radioprotection supervisors, both licensed by the Brazilian Nuclear Energy Commission (CNEN)

  4. Quality Management Audits in Nuclear Medicine Practices. 2. Ed

    International Nuclear Information System (INIS)

    Quality management systems are essential and should be maintained with the intent to continuously improve effectiveness and efficiency, enabling nuclear medicine to achieve the expectations of its quality policy, satisfy its customers and improve professionalism. The quality management (QM) audit methodology in nuclear medicine practice, introduced in this publication, is designed to be applied to a variety of economic circumstances. A key outcome is a culture of reviewing all processes of the clinical service for continuous improvement in nuclear medicine practice. Regular quality audits and assessments are vital for modern nuclear medicine services. More importantly, the entire QM and audit process has to be systematic, patient oriented and outcome based. The management of services should also take into account the diversity of nuclear medicine services around the world and multidisciplinary contributions. The latter include clinical, technical, radiopharmaceutical, medical physics and radiation safety procedures

  5. Analysis of the systems for management of radioactive wastes from nuclear medicine clinics of the city of Recife, Pernambuco, Brazil; Analise dos sistemas de gerenciamento de rejeitos radioativos de clinicas de medicina nuclear da cidade de Recife, PE

    Energy Technology Data Exchange (ETDEWEB)

    Lira, Renata Farias de; Lopes, Ferdinand de Jesus; Passos, Robson Silva; Silva, Valeria Cosma Bento da; Belo, Igor Burgo, E-mail: renatafariasdelira@hotmail.co, E-mail: ferdinand.lopes@oi.com.b, E-mail: robson.passos@hotmail.co, E-mail: Valleria_@hotmail.co, E-mail: Igor.burgo@gmail.co [Instituto Federal de Educacao, Ciencia e Tecnologia de Pernambuco, Recife, PE (Brazil); Santos, Marcus Aurelio Pereira dos, E-mail: masantos@cnen.gov.b [Centro Regional de Ciencias Nucleares (CRCN-NE/CNEN-PE), Recife, PE (Brazil)

    2009-07-01

    In nuclear medicine compounds marked with radionuclides, called radiopharmaceuticals, for obtention diagnostic information and for diseases treatment. The physicochemical characteristics of the radiopharmaceuticals determine his fixation at target-organ, and the physical characteristics determine the compound application in diagnostic or therapy. The handling of radiopharmaceuticals generates solid, liquid and gas wastes. The presence of these wastes implies in a adequate management according to regulation standards established by the Brazilian Nuclear Energy Commission (CNEN). The objective of safe management of radioactive wastes is to protect the human being and the preservation of the environment, limiting possible radiological impacts for the future generation, and comprehend a set of technical and administrative activities involved in the collection, segregation, handling, conditioning, transportation, storage, control and elimination, or the final deposition. This work intends to verify if the radioactive waste management systems from the nuclear medicine clinics at the city of Recife are conformal with te normative regulations issued by the CNEN. The initial obtained results are used to elaboration of conformal verification spreadsheet and its application in six nuclear medicine clinics at Recife

  6. Asian School of Nuclear Medicine

    International Nuclear Information System (INIS)

    The Asian School of Nuclear Medicine (ASNM) was formed in February 2003, with the ARCCNM as the parent body. Aims of ASNM: 1. To foster Education in Nuclear Medicine among the Asian countries, particularly the less developed ones. 2. To promote training of Nuclear Medicine Physicians in cooperation with government agencies, IAEA and universities and societies. 3. To assist in national and regional training courses, award continuing medical education (CME) points and provide regional experts for advanced educational programmes. 4. To work towards awarding of diplomas or degrees in association with recognized universities by distance learning and practical attachments, with examinations. The ASNM works toward a formal training courses leading to the award of a certificate in the long term. The most fundamental job of the ASNM remains the transfer of knowledge from the more developed countries to the less developed ones in the Asian region. The ASNM could award credit hours to the participants of training courses conducted in the various countries and conduct electronic courses and examinations. CME programmes may also be conducted as part of the regular ARCCNM meetings and the ASNM will award CME credit points for such activities

  7. The development of nuclear medicine in Slovenia and Ljubljana; half a century of nuclear medicine in Slovenia

    International Nuclear Information System (INIS)

    Nuclear medicine began to be developed in the USA after 1938 when radionuclides were introduced into medicine and in Europe after radionuclides began to be produced at the Harwell reactor (England, 1947). Slovenia began its first investigations in the 1950s. This article describes the development of nuclear medicine in Slovenia and Ljubljana. The first nuclear medicine interventions were performed in Slovenia at the Internal Clinic in Ljubljana in the period 1954–1959. In 1954, Dr Jože Satler started using radioactive iodine for thyroid investigations. In the same year, Dr Bojan Varl, who is considered the pioneer of nuclear medicine in Slovenia, began systematically introducing nuclear medicine. The first radioisotope laboratories were established in January 1960 at the Institute of Oncology and at the Internal Clinic. Under the direction of Dr. Varl, the laboratory at the Internal Clinic developed gradually and in 1973 became the Clinic for Nuclear Medicine with departments for in vivo and in vitro diagnostics and for the treatment of inpatients and outpatients at the thyroid department. The Clinic for Nuclear Medicine became a teaching unit of the Medical Faculty and developed its own post-graduate programme – the first student enrolled in 1972. In the 1960s, radioisotope laboratories opened in the general hospitals of Slovenj Gradec and Celje, and in the 1970s also in Maribor, Izola and Šempeter pri Novi Gorici. Nowadays, nuclear medicine units are modernly equipped and the staff is trained in morphological, functional and laboratory diagnostics in clinical medicine. They also work on the treatment of cancer, increased thyroid function and other diseases

  8. Edge tracing for the determination of the left ventricular projection, computer program and application for the clinic. Cardiac nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Tada, A. (Kanazawa Univ. (Japan). School of Medicine); Iwaki, Y.

    1981-09-01

    RI cardioangiography, especially blood pool scintigram which is made to synchronize with the cycles of electro-cardiogram, has been one of the two prime movers which, together with /sup 201/TlCl (thallium chloride) used in the study of myocardial blood flow, have contributed much to the development of the cardiovascular nuclear medicine, levelling it up to its present day state. Formerly, however, big computers and trained programmers were essential for the data processing of RI cardioangiography. Besides, only universities and research institutes could afford such expensive facilities. Nowadays, the situation has changed, and necessary data processing units have become available at considerably reduced costs. Even in common size city hospitals, cardioangiography has come to be applied for a routine practice in their medical examinations. Recently, Siemens Gammasonics, Inc. has put on sale a new system to replace the formerly introduced data processing unit called ''Scintiview''. It is the Auto Edge Detection System of the Left Ventricular to be used as a means of automatic cardiogram analysis program (ACAP). We have studied and reviewed differences of the setting-up methods of the region of interest which affect results of estimation of the left ventricular ejection fraction (EF).

  9. Where are we with nuclear medicine in pediatrics?

    International Nuclear Information System (INIS)

    The practice of nuclear medicine in children is different from that in adults. Technical considerations including immobilization, dosing of radiopharmaceuticals, and instrumentation are of major importance. Image mangnification and the capability to perform single-photon emission tomography are essential to performing state of the art pediatric nuclear medicine. New advances in instrumentation with multiple detector imaging, the possibility of clinical positron emission tomography imaging in children, and new radiopharmaceuticals will further enhance pediatric scintigraphic imaging. This review highlights advances in pediatric nuclear medicine and discusses selected clinical problems. (orig.)

  10. Perspectives in nuclear medicine: pulmonary studies

    International Nuclear Information System (INIS)

    Since the introduction of I-131 labeled macroaggregates in 1964, noninvasive techniques involving injection of radiolabeled agents and remote detection of emitted radiation have become well established in detecting pulmonary disorders in routine clinical medicine. In the past, pulmonary nuclear medicine has been dominated by studies that depict the distribution of pulmonary perfusion and/or ventilation-perfusion balance (e.g., for the detection of pulmonary embolism, obstructive airway disease, lung carcinoma). With the recent development of emission tomography and the potential for new, function-oriented radiopharmaceuticals, however, pulmonary nuclear medicine is entering a new era. The status of contemporary pulmonary nuclear medicine is briefly reviewed in several areas of major interest and applications and focus on areas where new developments are needed and seem feasible in the near future. Several important regional physiological processes measurable by these techniques include: (a) the presence or absence of pulmonary embolism, (b) relative pulmonary blood flow, (c) permeability to specific molecules, (d) lung tissue metabolism, (e) ventilation distribution and (f) the relationship between ventilation and blood flow (perfusion)

  11. Radiopharmaceutical activities administered for diagnostic procedures in nuclear medicine in the first six months of the gamma camera use in the Clinical Center of Montenegro - Podgorica

    International Nuclear Information System (INIS)

    Nuclear medicine procedures have carried out in the Clinical Center of Montenegro - Podgorica since 2006 by the dual-headed SPECT and Digital gamma camera NUCLINE Spirit DH-V. In the first six months of the gamma camera use (from September 2006 to March 2007) examinations of skeleton, kidneys, thyroid and lung were performed. For diagnostic skeletal imaging (102 patients) the radiopharmaceutical 99mTc-MDP is used, and administered activities were in the range from 555 to 740 MBq. For thyroid imaging (203 patients) 99mTc-pertechnetate is used, and administered activities were in the range (37-111) MBq. Lung imaging is performed for 3 patients, using 99mTc-MAA and administered activities in the range (111-185) MBq. Renal imaging is carried out for 72 patients: 42 dynamic studies of kidneys were performed with 99mTc-DTPA and administered activities from 207 to 282 MBq, and 30 static kidneys scintigraphies were performed using the radiopharmaceutical 99mTc-DMSA. 6 patients in the last mentioned group were children with year of birth between 2000 and 2006, and administered activities were from 16.6 to 55.5 MBq. In the same group, activities 28.5 MBq, 74.4 MBq and 120 MBq were administered to three patients with age between 6 and 18 years, and in the other cases, administered activities to the patients (adults) were in the range (59.2 to 196) MBq. The administered activities presented here are basis for further estimations of cumulated activity and absorbed dose to the various organs, which is useful for comparison of the average dose to patient organs in various nuclear medicine procedures and calculation of effective dose equivalent and total effective dose, significant for an estimation of potential risk due to the radioactivity administered to a patient during nuclear medicine procedures. It is very important for procedures optimization and improvement of the radiation protection. (author)

  12. Justification of the hybrid nuclear medicine examinations

    International Nuclear Information System (INIS)

    The annual frequency of nuclear medicine examinations is increasing worldwide. This is partly a consequence of the recently introduced single photon emission tomography, combined with computed tomography, and positron emission tomography, combined with computed tomography, techniques, which combine functional, metabolic and morphological information important for the diagnosis of many diseases. However, since the effective radiation dose is the sum of the dose of two components, the hybrid examinations result in increased patient exposure. Accordingly, their justification becomes mandatory. It starts with their clinical importance-the opportunity to resolve a clinical problem decisive for patients' management. Knowledge of the indications, contraindications and the examinations' limitations is the responsibility of the nuclear medicine physician, as well as the choice of the most adequate examination and protocol. In conclusion, the cost and the accessibility of the examinations should not be the principal consideration as opposed to the diagnostic value and the exposure. Flexible protocols and algorithms should be used for hybrid nuclear medicine examinations. (authors)

  13. Mongolia and nuclear medicine development

    International Nuclear Information System (INIS)

    Full text: Mongolia is a large, landlocked and sparsely populated country in the northern part of Central Asia, located between Russia on the north and China on east, south and west. Its total land area of 1.5 millions square kilometers is about the size if India or large than Alaska, but contains only 2.3 million population or 1.3 person per square kilometer. It is 2400 kilometers long from east to west maximum of 1260 kilometers from north to south.The priority problems in health.Democratic political reforms since 1990 saw a major transformation process, which is aimed at changing the centrally planned economy to one based on market orient principles. Mongolia is in a gradual epidemiological transition from preponderance of infectious diseases towards non-communicable and degenerative diseases. Mean features of this transition are sharp decrease in mortality from infectious and parasitic diseases and sharp increase in mortality from diseases of the circulatory system and neoplasms. Life expectancy at birth was 65.7 year in 1997. Cardiovascular diseases and cancer are among the leading causes of death in Mongolia.Nuclear Medicine in Mongolia-1975-1981 Beginning First Medical Application of radioisotopes in 1972. First Rectilinear scanner. Single and dual scintillation detectors system, Thyroid Uptake Test; 1982-1999 Settlement, IAEA TC Project since 1982, Thematic Program on Health Care (RAS) since 1997, First Gamma Camera since 1997, Radioimmunological Laboratory and first Radioiodine treatment since 1982, Mongolian Society of Nuclear Medicine since 1982, Member of World and Federation of Nuclear Medicine and Biology since 1994, Member of Asia and Oceania Radionuclide Therapy Council , 2000 Development, First SPECT and Quantitative Measurement in 2000 Second Gamma Camera, New Thyroid Uptake System-Atomlab 950 PC Spectrometer Radioimmunological Laboratory replacement, Myocardial Perfusion Scintigraphy, Liver Cancer Treatment with Re-188, Radiosynovectomy with Re

  14. Clinical trials and gender medicine

    Directory of Open Access Journals (Sweden)

    Mariarita Cassese

    2011-01-01

    Full Text Available Women use more medicines than men because they fall ill more often and suffer more from chronic diseases, but also because women pay more attention to their health and have more consciousness and care about themselves. Although medicines can have different effects on women and men, women still represent a small percentage in the first phases of trials (22% which are essential to verify drugs dosage, side effects, and safety. Even though women are more present in trials, studies results are not presented with a gender approach. This situation is due to educational, social, ethical and economical factors. The scientific research must increase feminine presence in clinical trials in order to be equal and correct, and all the key stakeholder should be involved in this process. We still have a long way to cover and it doesn't concern only women but also children and old people. The aim is to have a medicine not only illness-focused but patient-focused: a medicine able to take into consideration all the patient characteristics and so to produce a really personalized therapy. What above described is part of the reasons why in 2005 was founded the National Observatory for Women's Health (Osservatorio Nazionale sulla Salute della Donna, ONDa which promotes a gender health awareness and culture in Italy, at all the levels of the civil and scientific society.

  15. Spatial map dose of nuclear medicine service of the Clinical Hospital of Botucatu, SP, Brazil; Mapa espacial de dose do servico de medicina nuclear do Hospital das Clinicas de Botucatu

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Caio V.; Mendonca, Caroline; Silva, Eduardo T.; Moriguchi, Sonia M.; Koga, Katia H., E-mail: caiov_oliveira@yahoo.com.br [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucatu, SP (Brazil). Faculdade de Medicina

    2013-12-15

    This study was conducted to describe levels of occupational and environmental exposure of the Nuclear Medicine Service of the Clinical Hospital of Botucatu. To this end, measurements were made of the radiometric levels of points strategically defined, in all the environments, for a period of six months, sampling different days and times, during operation normal routine of the sector. The results allow to estimate the expected dose for each environment, comparing them to the dose limitation established by the National Commission of Nuclear Energy (CNEN), allowing better targeting of occupationally exposed individuals, indicating the points where the occupation should be the minimum required, enabling the reduction of risks to potential exposures. (author)

  16. New developments in nuclear medicine technology

    International Nuclear Information System (INIS)

    During the past few years, there have been new impulses in the development of a number of technologies employed in Nuclear Medicine imaging. These include new scintillation materials, the way of detecting the scintillation light, and completely novel methods to detect gamma rays by means of semiconductor detectors. In addition to combined instrumentation that can be used for SPECT and PET, already in clinical use, combined scintigraphic and anatomic imaging devices are now becoming available, for example SPECT/CT or PET/CT. This review article describes the most important of the new components, part of which have already entered product development and part of which are still in the research phase. The review focus on the employment of modern semiconductor detectors in Nuclear Medicine. (orig.)

  17. Radionuclides for routine diagnostics in nuclear medicine

    International Nuclear Information System (INIS)

    A survey is given on the radiopharmaceutics which are now in common use in nuclear medical diagnostics in vivo and in vitro. The development of radiopharmacology in the last 20 years has been characterized by the production of new and better radionuclides. A great step forward in clinical nuclear medicine has been the introduction of radionuclide generators for the production of short-lived nuclides. The most important and most generally used radionuclide for in vivo examinations is sup(99m)Tc pertechnetate. Tumour specific substances are still unknown, while the radioactive in vitro tests are of great clinical importance. They have opened up new possibilities of clinical laboratory diagnostics which are still not fully exploited. Special mention is made of the thyroid-specific in vitro tests in radiological thyroid diagnostics. (orig./AK)

  18. Coded-aperture imaging in nuclear medicine

    Science.gov (United States)

    Smith, Warren E.; Barrett, Harrison H.; Aarsvold, John N.

    1989-01-01

    Coded-aperture imaging is a technique for imaging sources that emit high-energy radiation. This type of imaging involves shadow casting and not reflection or refraction. High-energy sources exist in x ray and gamma-ray astronomy, nuclear reactor fuel-rod imaging, and nuclear medicine. Of these three areas nuclear medicine is perhaps the most challenging because of the limited amount of radiation available and because a three-dimensional source distribution is to be determined. In nuclear medicine a radioactive pharmaceutical is administered to a patient. The pharmaceutical is designed to be taken up by a particular organ of interest, and its distribution provides clinical information about the function of the organ, or the presence of lesions within the organ. This distribution is determined from spatial measurements of the radiation emitted by the radiopharmaceutical. The principles of imaging radiopharmaceutical distributions with coded apertures are reviewed. Included is a discussion of linear shift-variant projection operators and the associated inverse problem. A system developed at the University of Arizona in Tucson consisting of small modular gamma-ray cameras fitted with coded apertures is described.

  19. Draft report on the national seminar in nuclear medicine

    International Nuclear Information System (INIS)

    The proceedings of the seminar on nuclear medicine have been conducted in four main sessions. In the first session a review of the current status of clinical nuclear medicine in India is reviewed. The use of radioisotopes in thyroid function studies, central nervous systems, liver disorders, lung and bone imaging, renal function studies, dynamic function studies, gastroenterology haematology etc. are described. The existing facilities and the future needs for radioimmunoassay and radiotherapy are discussed. In Session 2, the existing facilities in nuclear medicine in different states in India are reviewed. In Session 3, the available resources in nuclear medicine are reviewed. Radiation protection procedures are outlined. Various nuclear instruments developed at the Bhabha Atomic Research Centre, (BARC), Bombay, for use in nuclear medicine are briefly described. A list of radiopharmaceuticals developed by BARC and in current use, is given. The roles of the physicist, pharmacist and the nuclear medicine technologist in the hospitals having nuclear medicine units, are stressed. The importance of training and education for personnel in nuclear medicine and medical physics is pointed out. (A.K.)

  20. Clinical use of quantitative cardiac perfusion PET: rationale, modalities and possible indications. Position paper of the Cardiovascular Committee of the European Association of Nuclear Medicine (EANM).

    Science.gov (United States)

    Sciagrà, Roberto; Passeri, Alessandro; Bucerius, Jan; Verberne, Hein J; Slart, Riemer H J A; Lindner, Oliver; Gimelli, Alessia; Hyafil, Fabien; Agostini, Denis; Übleis, Christopher; Hacker, Marcus

    2016-07-01

    Until recently, PET was regarded as a luxurious way of performing myocardial perfusion scintigraphy, with excellent image quality and diagnostic capabilities that hardly justified the additional cost and procedural effort. Quantitative perfusion PET was considered a major improvement over standard qualitative imaging, because it allows the measurement of parameters not otherwise available, but for many years its use was confined to academic and research settings. In recent years, however, several factors have contributed to the renewal of interest in quantitative perfusion PET, which has become a much more readily accessible technique due to progress in hardware and the availability of dedicated and user-friendly platforms and programs. In spite of this evolution and of the growing evidence that quantitative perfusion PET can play a role in the clinical setting, there are not yet clear indications for its clinical use. Therefore, the Cardiovascular Committee of the European Association of Nuclear Medicine, starting from the experience of its members, decided to examine the current literature on quantitative perfusion PET to (1) evaluate the rationale for its clinical use, (2) identify the main methodological requirements, (3) identify the remaining technical difficulties, (4) define the most reliable interpretation criteria, and finally (5) tentatively delineate currently acceptable and possibly appropriate clinical indications. The present position paper must be considered as a starting point aiming to promote a wider use of quantitative perfusion PET and to encourage the conception and execution of the studies needed to definitely establish its role in clinical practice. PMID:26846913

  1. The application of nuclear-medicine methods in veterinary medicine

    International Nuclear Information System (INIS)

    X-radiography and ultrasound imaging are well established and widely used in veterinary practice, but it is not the same situation with radioisotope imaging. In veterinary practice the above mentioned methods of nuclear medicine are developed only in two countries in Europe. That is not doubt due, so bar, to the difficulties in obtaining satisfactory supply of radioisotopes and to the relatively high cost of scanning equipment. However, in collaboration with the Department of Radiation Protection and Nuclear Medicine of the Medical Faculty in Zagreb, Croatia, we have chance to develop the use of those methods in clinical veterinary practice in Zagreb. That is way in this paper an overview of the application of radioisotopes imaging in veterinary medicine is given. In small animals skeletal changes, lung perusions, brain lesions, space occupying lesions in the liver and its function and hearth function can be usefully searched by a gamma camera and its associated computer. In equine practice scintigraphy of bones, liver, hearth, pulmonary circulation and ventilation is described. The largest amount of radioactive material is used during gamma camera scanning of the skeletons of horses. In this cases the radiation dose 1-2 m from the animal is approximately 3 μSv/h. That is why the protection of personal involved in radioisotope scanning in veterinary medicine must be also regulated by low of radiation protection. Also, the animals should be confined to a controlled area for 2-3 days after scanning before being returned to their owners. After this period the area must be cleaned. (author)

  2. Teaching of nuclear medicine at medical faculties

    International Nuclear Information System (INIS)

    The teaching of nuclear medicine at medical faculties in the CSSR is analyzed. It is shown that the teaching conditions are different at the individual faculties of medicine and the respective conditions are exemplified. (author). 4 tabs

  3. Quality assurance in nuclear medicine

    International Nuclear Information System (INIS)

    Most of the procedures in nuclear medicine deal with generation of functional images of various organs. By using appropriate software programmes various parameters of organ functions are derived. Due to automation and software refinements quality control of instrumentation has greatly improved. By introducing a QA programme significant improvement of image quality can be achieved. The percentage of retake of films can be drastically reduced. The financial gain can be substantial yielding to cost effectiveness of procedures. Continuous monitoring backed by effective communication and feedback from patients, referring physicians and payers of health care is essential to maintain a viable and responsive QA programme

  4. Closing the gap between theory and practice in Nuclear Medicine

    International Nuclear Information System (INIS)

    Aim: The ultimate goal for any clinical teaching program is to have students who demonstrate clinical competence. The Nuclear Medicine Technologist like any health professional should graduate from their course: attaining a defined standard of core knowledge; demonstrating appropriate behaviour for the workplace; and, achieving a predetermined level of clinical skill. In the University of Sydney Nuclear Medicine course, revisions were made to the Clinical Education assessment tools to create a more incremental approach and define competencies that required a higher level of achievement. Nuclear Medicine theory delivery was changed to create a more contextual environment where the student was better prepared for the workplace. The aim of this study is firstly to analyse the relationship between assessment of contextual theory and assessment of clinical practice. A secondary aim is to investigate any relationship between individual clinical assessment tools. Clinical assessment tools include: clinical competencies; observed clinical skills examinations (OSCE); clinical and university supervisor assessments; and assignments. Nuclear Medicine theory assessment tools include: problem oriented teamwork presentations; assignment; and written examination. Method: Correlation of the students' overall marks in the subjects' Nuclear Medicine theory and Clinical Education in the years 2000 and 2001 was undertaken using SPSS. Correlation of the students' scores in the individual clinical assessment tools: Clinical Supervisor to University supervisor; Clinical Supervisor to OSCE; and University Supervisor to OSCE, was completed for the years 2000 and 2001. Results: A statistically significant correlation was found for the students' marks in Nuclear Medicine theory and Clinical Education for the same year. The University and Clinical Supervisors' results significantly correlated for all years. Correlation between the individual assessment tools used in Clinical Education was not

  5. Nuclear Medicine Imaging in Pediatric Neurology

    OpenAIRE

    Ümit Özgür Akdemir; Lütfiye Özlem; Atay Kapucu

    2016-01-01

    Nuclear medicine imaging can provide important complementary information in the management of pediatric patients with neurological diseases. Pre-surgical localization of the epileptogenic focus in medically refractory epilepsy patients is the most common indication for nuclear medicine imaging in pediatric neurology. In patients with temporal lobe epilepsy, nuclear medicine imaging is particularly useful when magnetic resonance imaging findings are normal or its findings are discordant with e...

  6. Nuclear medicine resources in the internet

    International Nuclear Information System (INIS)

    The internet is a global collection of networked computers linked by a set of protocols which allows the otherwise disperate computer systems to communicate with each other. In contrast to text-only data available previously, the World Wide Web allows multimedia content to be available on the internet. Graphics can now likewise be used as links. The development of World Wide Web client software such as Mosaic, or the currently more popular Netscape Navigator, makes linking from one document to another (colloquially referred to as 'surfing the Net') fast and simple. While these software are commonly called Web browsers their function extends to the other internet services such as e-mail, file transfer protocol, remote login, Gopher and WAIS. A prototype application being developed as a case-based teaching file which could include clinical data and case discussion, aside of course from the nuclear medicine and related images. Contributions from various institutions can be made available on their own servers and linked together through hypertext. Examples of these are websites of the Mallinckrodt Institute of Radiology and the Joint Program in Nuclear Medicine of the Harvard Medical School. The university of Iowa also has its Virtual Hospital, a collection of clinical cases with radiologic images. Most major universities and medical centers have websites where information on on-going research, facilities and personnel are made available. Links to various special interest discussion groups (e.g. those developing the common image file format) are also accessible and the documents often contain further links to related fields in nuclear technology. The very nature of the hypertext transfer protocol of the World Wide Web makes it a relatively simple matter for a developer of a teaching system to include links to necessary resources. It is envisioned that an internet-based teaching module will be incorporated in some nuclear medicine training programs in the United States

  7. Recommendations on Strengthening the Development of Nuclear Medicine in China

    Institute of Scientific and Technical Information of China (English)

    Shih-chen Wang

    2009-01-01

    @@ This paper outlines briefly the role of nuclear medicine in life sciences and health care. Molecular imaging by using isotopic tracers can noninvasively visualize the chemistry or hidden process in the cells and tissues inside the body, obtaining "functional" images to provide early information of any disease and revealing the secrets of life. The vitality of nuclear medicine is its ability to translate bench into new clinical application that can benefits the patients. Although nuclear medicine community in China has made significant achievement with a great effort since 1950s, there are many obstacles to future development. Recommended measures are proposed here in an attempt to solve our existing problems.

  8. Dementia and rural nuclear medicine

    International Nuclear Information System (INIS)

    Full text: The rapid increase in dementia is directly related to the growing number of aged people in developed countries, such as Australia. This increase heightens the need for accurate dementia diagnosis to ensure treatment resources are appropriately allocated. However, current diagnostic methods are unable to determine specific dementia types limiting the effectiveness of many care plans. The lack of specialist resources in rural Australian communities presents nuclear medicine with an opportunity to make a significant impact on the management of this disease. This investigation aimed to identify how SPECT perfusion imaging could maximise its role in the management of dementia in a rural New South Wales setting. The study reviewed all Technetium 99m HMPAO SPECT brain studies over a three-year period. This included a medical record audit, review of all diagnostic imaging reports and an analysis of referral patterns. The results of this study provide compelling evidence that, even in a rural setting, brain SPECT, in conjunction with neuropsychological testing, offers high accuracy in determining the presence and type of dementia. In addition, the study found more than 30% of referrers had no training in SPECT, emphasising the importance of ensuring that brain SPECT reports, in a rural setting, educate and specify to referrers the significance and exact disease type found in the study. Copyright (2003) The Australian and New Zealand Society of Nuclear Medicine Inc

  9. Pulmonary applications of nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine techniques have a long history in pulmonary medicine, one that has been continually changing and growing. Even longstanding methods, such as perfusion scanning for embolic disease or for pretherapy pulmonary function evaluation, have largely withstood the test of recent careful scrutiny. Not only have these techniques remained an important part of the diagnostic armamentarium, but we have learned how to use them more effectively. Furthermore, because of technical advances, we are in a phase of expanding roles for nuclear imaging. Gallium citrate scanning for the mediastinal staging and follow-up of lymphoma has been recognized as a valuable adjunct to the anatomic information provided by CT and MRI. With the growth of PET technology in areas that have been explored in a limited fashion until now, such as noncardiogenic pulmonary edema and lung carcinoma, evaluation and management of these patients may substantially improve. Finally, in the field of radiolabeled monoclonal antibodies, attention is now being turned to both the diagnostic and the therapeutic problems presented by lung carcinoma. As radiolabeling methods are refined and as new and better antibodies are developed, radioimmunodetection and therapy in lung carcinoma may begin to make inroads on this common and hard to control disease.157 references

  10. Equipment used in nuclear medicine

    International Nuclear Information System (INIS)

    Detection of radiation is the common purpose of all equipment's and instruments used in radioisotope laboratories. The first and most important instrument that was used in nuclear medicine was Geiger tube developed by H.W. Geiger as early in 1908. He in association with Mueller developed the so called Geiger-Muller tube (GM tube) which could be used to detect beta and gamma radiations. In spite of its severe limitations, GM tube remained the only external counting device until 1949. In 1948, Kallman reported that the scintillations can be detected and amplified with the help of photomultiplier tubes (PMTs). In comparison with gas filled detectors, scintillation detectors have two principal advantages that augment their use in nuclear medicine. Firstly, they are capable of much higher counting rates because of fast resolving times and secondly, because they are much more efficient for gamma ray detection. The scintillation detector is the most basic block of any modern radioisotope detection instrument like rate meter, counter, scanner, gamma camera or single photon emission computed tomography. (author)

  11. Nuclear medicine applications in AIDS

    International Nuclear Information System (INIS)

    Full text: Aids patients are liable to more than one medical problem at anyone time as the number of CD4 cells decrease and the viral load increases. Problems are related to multiple causes of opportunistic Infections, malignant lymphoma and Kaposi sarcoma. Laboratory tests, sputum analysis and bronchial lavage have problems of decreased sensitivity. morphologic Imaging modalities such as chest X-ray, CT or MRI has problems of specificity. Nuclear medicine techniques has the advantage of total body functional imaging that can visualize more than one organ. The use nuclear medicine imaging is recommended when the diagnosis is uncertain and for initiation of proper treatment. Gallium-67 citrate total body scans acquired at 4 hours following the IV injection and at 24-48 hours has been very useful for the early diagnosis of opportunistic infections such as PCP, TB, Disseminated Mycobacterium avii complex; MAI, malignant lymphoma and various forms of AIDS related colitis. Sequential thallium and gallium scan help to differentiate Kaposi sarcoma (thallium positive, gallium negative) from opportunistic infections (gallium positive, thallium negative) and malignant lymphoma (thallium and gallium positive). Gallium is the most convenient radiopharmaceutical for the diagnosis of malignant lymphoma of the heart. Thallium and Tc-99m Sestamibi are useful for the differentiation of intracranial toxoplasmosis from malignant lymphoma. The presentation will illustrate different examples and will explain the limitations of all these tests. (author)

  12. ICRP 60 and nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Galli, G. (Rome Univ. Cattolica del S. Cuore (Italy). Ist. di Medicina Nucleare)

    For that which regards the field of nuclear medicine, the new International Commission on Radiation Protection recommendations (ICRP 60) are highly innovative in that the differentiation between 'controlled' and ' monitored' areas is no longer tied to fractions of annual dose limits, but it is instead established locally on the basis of operational experience and judgement. The most notable feature of the new recommendations, however, concerns the new 20 mSv dose limit for exposed workers, the 1 mSv limit for the public (understood as the 5 year annual average), as well as, the modifications to the annual limits on the intake of radionuclides, e.g., inhalation of I 131 passes from 2*10/sup 6/ to 1*10/sup 6/. This paper assesses the impacts of these new limits on the performance of ' in vivo' medical diagnostics and radio-metabolic therapy with unsealed sources. Attention is given to possible negative consequences on the implementation of nuclear medicine due to the current trend towards lower limits, and to the implications of the new recommendations as regards medical support staff and family members of individuals undergoing radiotherapy.

  13. Radiosanitary control in nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear Medicine has recently modified radiosanitary control standards for the three sectors involved: patients, personnel and general population. Nuclear Medicine does not constitute an important source of radiation, including patients and population, compared with radiology. The basic problems of radiosanitary controls are: the absorbed dose and the patient. Low risk deferred stochastic effects may appear with correct use of these controls. On the other hand, risk of stochastic consequences and non stochastic complications appear with incorrect applications. The following aspects should be considered for correct uses: A-1- The critical organ, which is not always the one under study. 2-The rest of the organism, specially the more sensitive organs. B- The radiopharmaceutical used, considering the following periods: physical, biological and effective. C-Technical and human resources that include quality control for the equipment. Radiosanitary control aims at a common objetive: dose limitation to the patient, personnel and general population. For this, it is necessary to accomplish the training programme for proffesional and technical personnel about quality control and to stablish basic standards for the equipment. Current law and regulations assign to the National Atomic Energy Comission the responsibility for controlling the use of radioisotopes and radiations in order to safeguard the health and life of the population. (M.E.L.)

  14. Positron in nuclear medicine imaging

    International Nuclear Information System (INIS)

    The last two decades have witnessed a rapid expansion of clinical indications of positron emission tomography (PET) based imaging in assessing a wide range of disorders influencing their clinical management. This is primarily based upon a large dataset of evidence that has been generated over the years. The impact has been most remarkable in the field of cancer, where it takes a pivotal role in the decision making (at initial diagnosis, early response assessment and following completion of therapeutic intervention) of a number of important malignancies. The concept of PET based personalized cancer medicine is an evolving and attractive proposition that has gained significant momentum in recent years. The non-oncological applications of PET and PET/CT are in (A) Cardiovascular Diseases (e.g. Myocardial Viability, Flow reserve with PET Perfusion Imaging and atherosclerosis imaging); (B) Neuropsychiatric disorders (e.g. Dementia, Epileptic Focus detection, Parkinson's Disease, Hyperkinetic Movement Disorders and Psychiatric diseases); (C) Infection and Inflammatory Disorders (e.g. Pyrexia of Unknown origin, complicated Diabetic Foot, Periprosthetic Infection, Tuberculosis, Sarcoidosis, Vasculitic disorders etc). Apart from these, there are certain novel clinical applications where it is undergoing critical evaluation in various large and small scale studies across several centres across the world. The modality represents a classical example of a successful translational research of recent times with a revolutionary and far-reaching impact in the field of medicine. (author)

  15. Special monitoring in nuclear medicine

    International Nuclear Information System (INIS)

    Colombia counts with around 56 centers of Nuclear Medicine, 70 Nuclear Doctors and more of 100 Technologists in this area. The radioisotopes more used are the 131 I and the 99m Tc. The radiological surveillance singular in the country is carried out for external dosimetry, being the surveillance by incorporation of radioactive materials very sporadic in our media. Given the necessity to implement monitoring programs in the incorporation of radionuclides of the occupationally exposed personnel, in the routine practice them routine of Nuclear Medicine, it was implemented a pilot program of Special Monitoring with two centers of importance in the city of Medellin. This program it was carried out with the purpose of educating, to stimulate and to establish a program of reference monitoring with base in the National Program of Monitoring in the radionuclides Incorporation that serves like base for its application at level of all the services of Nuclear Medicine in the country. This monitoring type was carried out with the purpose of obtaining information on the work routine in these centers, form of manipulation and dosage of the radionuclides, as well as the administration to the patient. The application of the program was carried out to define the frequency of Monitoring and analysis technique for the implementation of a program of routine monitoring, following the recommendations of the International Commission of Radiological Protection. For their application methods of activity evaluation were used in urine and in 7 workers thyroid, of those which only two deserve an analysis because they presented important activities. The measures were carried out during one month, every day by means in urine samples and to the most critic case is practiced two thyroid measures, one in the middle of the period and another when concluding the monitoring. To the other guy is practiced an activity count in thyroid when concluding the monitoring period. The obtained result of the

  16. NCT program at Nuclear Medicine, Inc

    International Nuclear Information System (INIS)

    The Neutron Capture Therapy program at Nuclear Medicine, Inc. (NMI) is focused on obtaining Food and Drug Administration (FDA) approval of the treatment for malignant brain tumors. To minimize both the time and expense of the approval process, research efforts have been strictly focused and Orphan Drug sponsorship of the boron compound, Na2B12H11SH, has been obtained. The significance of Orphan Drug sponsorship and NMI's initial meeting with the FDA to discuss preclinical and clinical protocols are discussed. 9 references, 2 figures

  17. [Solid liver mass. Studies with nuclear medicine].

    Science.gov (United States)

    Domínguez Gadea, L; Fernández Salazar, L; García Grávalos, R; Rodríguez Eyré, J L

    2000-04-01

    We present the case of a 23 year old female with two incidentally detected hepatic mass that have not clinically o radiologically specific findings. Nuclear medicine tracers, including colloids and hepatobiliary agents showing the characteristic findings of focal nodular hyperplasia: Hypervascularization, normal uptake of colloids, accumulation of hepatobiliary tracer and hot spots due to the retention of this tracer during the clearance fhase. The patient was underwent hepatectomy. The examination of surgical specimen revealed focal nodular hyperplasia. The scintigraphic studies could be an useful tool in the noninvasive diagnosis of liver masses. PMID:10893773

  18. Current Status of The Korean Society of Nuclear Medicine

    International Nuclear Information System (INIS)

    As the application of nuclear medicine to clinics became generalized and it held an important position, the Korean Society of Nuclear Medicine was founded in 1961, and today it has become known as one of the oldest nuclear medicine societies not only to Asian nations but also to other advanced countries all over the world. Now it has 100 or so regular members composed of students of each medicine filed unlike other medical societies. Only nuclear medicine research workers are eligible for its membership. The Korean Society of Nuclear Medicine holds its regular general meeting and symposium twice per annom respectively in addition to occasional group gatherings and provincial lectures on nuclear medicine. With an eye to exchanging information on symposium, research and know-how, KSNM issued its initial magazine in 1967. Every year two editions are published. Year after year the contents of treatises are getting elevated with researches on each field including the early study on morphology-greatly improved both in quality and quantity. Of late, a minute and fixed quantity of various matters by dynamical research and radioimmunoassay of every kind has become visibly active. In particular, since KSNM, unlike other local societies, keeps close and frequent contact with the nuclear medicine researchers of world-wide fame, monographs by eminent scholars of the world are carried in its magazine now internationally and well received in foreign countries. Now the magazine has been improved to such an extent that foreign authors quote its contents. KSNM invited many a foreign scholar with a view to exchanging the knowledge of nuclear medicine. Sponsored by nuclear energy institute, the nuclear medicine symposium held in Seoul in October of 1966 was a success with Dr. Wagner participating, a great scholar of world wide fame: It was the first international symposium ever held in Korea, and the Korea Japan symposium held in Seoul 1971 was attended by all distinguished nuclear

  19. Introduction to hardware for nuclear medicine data systems

    International Nuclear Information System (INIS)

    Hardware included in a computer-based data system for nuclear medicine imaging studies is discussed. The report is written for the newcomer to computer collection and analysis. Emphasis is placed on the effect of the various portions of the system on the final application in the nuclear medicine clinic. While an attempt is made to familiarize the user with some of the terms he will encounter, no attempt is made to make him a computer expert. 1 figure, 2 tables

  20. Nuclear medicine - the condition and prospects

    International Nuclear Information System (INIS)

    Full text: The nuclear medicine has rather strongly determined the place in clinical and diagnostic practice. Statistical researches show, that, even despite of the certain successes in treatment of many diseases, rather high death rate at cardiovascular, oncological and many other diseases. The urgency of clinical tasks connected with a state of health of the population puts before nuclear medicine a (task) on development and introduction of new methods of diagnostics and therapy. The nuclear medicine is characterized by some number of diagnostic and therapeutic methods which application frequently does not have other alternative. The methods of visualization used in nuclear medicine, are full informative, exact and have ability to reveal structurally functional changes of bodies and fabrics practically at a cellular level. To present time diagnostic radiopharmacy (Ph) wed practically in all clinical areas of medicine. In world practice steady growth of increase of manufacture as diagnostic and radiotherapeutic RP was planned. The even greater (reduction) of potential risk one and of conditions by which development of nuclear medicine in the near future is defined is at realization of the procedures connected to application of radioactive preparations and reduction of beam loadings on the patient. An important point in the clinic-diagnostic field is replacement the RP on short-lived and ultra short-lived. Among examples of such transition it is necessary to name replacement 131I in diagnostic application on 123I, and also active introduction PET. It is possible to call essentially new direction of development of technologies of the directed transport the open radioactive isotopes and RP to pathology changed bodies or organisms demanding realization of diagnostic procedures or selective beam therapy. However, despite of huge potential opportunities of the domestic nuclear industry, even such old method as the radiotherapy I-131 - is used by iodine in our country in

  1. Clinical Holistic Medicine: Holistic Adolescent Medicine

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2004-01-01

    Full Text Available The holistic medical approach seems to be efficient and can also be used in adolescent medicine. Supporting the teenager to grow and develop is extremely important in order to prevent many of the problems they can carry into adulthood. The simple consciousness-based, holistic medicine — giving love, winning trust, giving holding, and getting permission to help the patient feel, understand, and let go of negative beliefs — is easy for the physician interested in this kind of practice and it requires little previous training for the physician to be able to care for his/her patient. A deeper insight into the principles of holistic treatment and a thorough understanding of our fellow human beings are making it work even better. Holistic medicine is not a miracle cure, but rather a means by which the empathic physician can support the patient in improving his/her future life in respect to quality of life, health, and functional capacity — through coaching the patient to work on him/herself in a hard and disciplined manner. When the patient is young, this work is so much easier. During our lifetime, we have several emotional traumas arranged in the subconscious mind with the smallest at the top, and it is normal for the person to work on a large number of traumatic events that have been processed to varying degrees. Some traumas have been acknowledged, some are still being explored by the person, and yet others are still preconscious, which can be seen for example in the form of muscle tension. Sometimes the young dysfunctional patient carries severe traumas of a violent or sexual nature, but the physician skilled in the holistic medical toolbox can help the patient on his/her way to an excellent quality of life, full self-expression, a love and sex life, and a realization of his/her talents — all that a young patient is typically dreaming about. Biomedicine is not necessary or even recommended when the physical or mental symptoms are caused

  2. Role of nuclear medicine in imaging companion animals

    International Nuclear Information System (INIS)

    The role of equine nuclear medicine in Australia has been previously described in this journal and more recently, Lyall et al. provided a general overview of demographics of veterinary nuclear medicine departments in Australia. Lyall et al. discuss the main clinical applications of nuclear medicine scintigraphy in companion animals; dogs and cats. The aim of this article is to discuss in brief the applications of commonly performed nuclear medicine procedures in humans with respect to veterinary applications. More detailed discussion will also be offered for investigation of pathologies unique to veterinary nuclear medicine or which are more common in animals than humans. Companion animals are living longer today due to advances in both veterinary and human medicine. The problem is, like humans, longevity brings higher incidence of old age morbidity. As a pet owner, one might be initially motivated to extend life expectancy which is followed by the realisation that one also demands quality of life for pets. Early detection through advanced diagnostic tools, like nuclear medicine scintigraphy, allows greater efficacy in veterinary disease. There are limited veterinary nuclear medicine facilities in Australia due to cost and demand. Not surprisingly then, the growth of veterinary nuclear medicine in Australia, and overseas, has been integrally coupled to evaluation of race horses. While these facilities are generally specifically designed for race horses, racing greyhounds, lame family horses and companion animals are being investigated more frequently. In the USA, the American College of Veterinary Radiology (ACVC) is very active clinically and in research. The ACVC journal, Journal of Veterinary Radiology and Ultrasound, is published quarterly and includes a Nuclear Medicine section. Within the ACVR is the Society of Veterinary Nuclear Medicine. Proliferation of veterinary nuclear medicine centres in the USA has been associated with insurance and lifestyle changes

  3. Value measurement of nuclear medicine procedures

    International Nuclear Information System (INIS)

    The difficulty in measuring the benefit component for cost/benefit analysis of diagnostic procedures in medicine is portrayed as a complex issue relating the objective of intent to a classification of types of decisions a physician must make in evaluating a patient's problem. Ultimately, it seems desirable to develop measuring instruments such as attitude measurement tools by which the relative value of alternative diagnostic procedures could be measured in terms of what they contribute to diminishing the patient's personal perception of disease. Even without this idealized objective, it is reasonable to assume that diagnostic tests which do not contain information, defined as a change in the randomness of a state of knowledge, could not be expected to ultimately benefit the patient. Thus diagnostic information should provide a rational direction for the physician to modify the course of the patient's illness. Since information can be measured as a change in randomness of a knowledge state, we can determine the information content of a specific nuclear medicine procedure when faced with an array of diagnostic problems. These measurements remain to be made for clinical nuclear medicine procedures and are currently under study

  4. Structure and Activities of Nuclear Medicine in Kuwait.

    Science.gov (United States)

    Elgazzar, Abdelhamid H; Owunwanne, Azuwuike; Alenezi, Saud

    2016-07-01

    The practice of nuclear medicine in Kuwait began in 1965 as a clinic for treating thyroid diseases. The practice developed gradually and until 1981 when the Faculty of Medicine established the Division of Nuclear Medicine in the Department of Radiology, which later became a separate department responsible for establishing and managing the practice in all hospitals of Kuwait. In 1987, a nuclear medicine residency program was begun and it is administered by Kuwait Institute for Medical Specializations originally as a 4-year but currently as a 5-year program. Currently there are 11 departments in the ministry of health hospitals staffed by 49 qualified attending physicians, mostly the diplomats of the Kuwait Institute for Medical Specializations nuclear medicine residency program, 4 academic physicians, 2 radiopharmacists, 2 physicists, and 130 technologists. These departments are equipped with 33 dual-head gamma cameras, 10 SPET/CT, 5 PET/CT, 2 cyclotrons, 1 breast-specific gamma imaging, 1 positron-emitting mammography, 10 thyroid uptake units, 8 technegas machines, 7 PET infusion systems, and 8 treadmills. Activities of nuclear medicine in Kuwait include education and training, clinical service, and research. Education includes nuclear medicine technology program in the Faculty of Allied Health Sciences, the 5-year residency program, medical school teaching distributed among different modules of the integrated curriculum with 14 didactic lecture, and other teaching sessions in nuclear medicine MSc program, which run concurrently with the first part of the residency program. The team of Nuclear Medicine in Kuwait has been active in research and has published more than 300 paper, 11 review articles, 12 book chapters, and 17 books in addition to 36 grants and 2 patents. A PhD program approved by Kuwait University Council would begin in 2016. PMID:27237444

  5. Links between nuclear medicine and radiopharmacy

    International Nuclear Information System (INIS)

    Radiopharmaceuticals are nowadays under the responsibility of the radio-pharmacist because of their medicinal product status. Radiopharmacy belongs to the hospital pharmacy department, nevertheless, interactions with nuclear medicine department are important: rooms are included or located near nuclear medicine departments in order to respect radiation protection rules, more over staff, a part of the material and some activities are shared between the two departments. Consequently, it seems essential to formalize links between the radiopharmacy and the nuclear medicine department, setting the goals to avoid conflicts and to ensure patients' security. Modalities chosen for this formalization will depend on the establishment's organization. (authors)

  6. Nuclear Medicine Technology: A Suggested Postsecondary Curriculum.

    Science.gov (United States)

    Technical Education Research Center, Cambridge, MA.

    The purpose of this curriculum guide is to assist administrators and instructors in establishing nuclear medicine technician programs that will meet the accreditation standards of the American Medical Association (AMA) Council on Medical Education. The guide has been developed to prepare nuclear medicine technicians (NMT's) in two-year…

  7. Radionuclides for nuclear medicine: a nuclear physicists' view

    Czech Academy of Sciences Publication Activity Database

    Cantone, M.; Haddad, F.; Harissopoulos, S.; Jensen, M.; Jokinen, A.; Koster, U.; Lebeda, Ondřej; Ponsard, B.; Ratzinger, U.; Stora, T.; Tarkanyi, F.; Van Duppen, P.

    2013-01-01

    Roč. 40, 2 Supplement (2013), S257-S257. ISSN 1619-7070. [Annual Congress of the European Association of Nuclear Medicine (EANM). 19.10.2013-23.10.2013, Lyon] Institutional support: RVO:61389005 Keywords : nuclear physics for medicine * EANM * medical radionuclides Subject RIV: BG - Nuclear , Atomic and Molecular Physics, Colliders

  8. Nuclear Medicine at Charles Sturt University

    International Nuclear Information System (INIS)

    Full text: A distance educational programme for upgrading of Certificate, Associate Diploma and Diploma to a Bachelor of Applied Science degree commenced in second semester of 1997 with approximately 15 Australian students and 15 Canadian students. The first graduation will occur in 1998. Formal links with the Michener Institute in Toronto have allowed Canadian students access to study resources during the course. All students entering the course are accredited or registered with their respective professional societies. The short conversion programme for those with three year diplomas includes Nuclear Medicine Physics and Instrumentation, Imaging Pathology, Clinical Neuroscience and Research Method subjects. An inaugural undergraduate degree programme in Nuclear Medicine Technology commences in first semester of 1998 on the Riverina Campus at Wagga Wagga. An intake of 15 students is anticipated. This small group of rural based students will have the benefits of international expertise. The programme has a strong clinical practice component including time on campus to supplement the practicum in departments. Physiology studies continue through to third year to complement the professional subjects. Active participation is solicited from those departments involved with aspects of the practicum well before students are placed. A fully functional teaching laboratory has been constructed containing a well equipped radiopharmacy, gamma camera room and computer laboratory using modern applications software to provide the students with a solid background in their chosen field

  9. Nuclear Medicine at Charles Sturt University

    Energy Technology Data Exchange (ETDEWEB)

    Swan, H. [Charles Sturt University, Wagga Wagga, NSW (Australia); Sinclair, P. [Charles Sturt University, Dubbo, NSW (Australia); Scollard, D. [Michener Institute, Toronto (Canada)

    1998-06-01

    Full text: A distance educational programme for upgrading of Certificate, Associate Diploma and Diploma to a Bachelor of Applied Science degree commenced in second semester of 1997 with approximately 15 Australian students and 15 Canadian students. The first graduation will occur in 1998. Formal links with the Michener Institute in Toronto have allowed Canadian students access to study resources during the course. All students entering the course are accredited or registered with their respective professional societies. The short conversion programme for those with three year diplomas includes Nuclear Medicine Physics and Instrumentation, Imaging Pathology, Clinical Neuroscience and Research Method subjects. An inaugural undergraduate degree programme in Nuclear Medicine Technology commences in first semester of 1998 on the Riverina Campus at Wagga Wagga. An intake of 15 students is anticipated. This small group of rural based students will have the benefits of international expertise. The programme has a strong clinical practice component including time on campus to supplement the practicum in departments. Physiology studies continue through to third year to complement the professional subjects. Active participation is solicited from those departments involved with aspects of the practicum well before students are placed. A fully functional teaching laboratory has been constructed containing a well equipped radiopharmacy, gamma camera room and computer laboratory using modern applications software to provide the students with a solid background in their chosen field

  10. Guidelines on QC for nuclear medicine instrumentation

    International Nuclear Information System (INIS)

    Full text: In 2005, a working group of The European Association of Nuclear Medicine (EANM) was set up to provide nuclear medicine practitioners with general guidelines on the quality control of equipment used in the practice of nuclear medicine. In diagnostic nuclear medicine, the quality assurance objective is the provision of high quality, reproducible data that would provide the required clinical information with the smallest radiation burden to the patient. Quality assurance programmes must ensure the most effective use of available equipment and must ensure that processes are in place to minimize clinical risk. Our guidelines focus on the quality control (QC) procedures used in nuclear medicine with a special focus on new, sophisticated, digital technologies. The guidelines have been written as a tool designed to promote the cost-effective use of high quality nuclear medicine instrumentation and to aid practitioners in ensuring accurate information is obtained from each nuclear medicine examination. The purpose of these guidelines is to assist practitioners in achieving their clinical objective and, as such, they are general recommendations on good practice which should be applicable across national boundaries. Routinely, quality control procedures are required to ensure that nuclear medicine equipment is functioning correctly. These quality control tests are intended to detect problems of the systems before they impact on clinical patient studies. They are not intended to provide a full evaluation of equipment performance. Further tests may be required to trace the cause of the problem and to ensure that the equipment is performing properly after service or adjustment. Our QC guidelines cover both imaging and other measuring (non-imaging) equipment including planar gamma cameras, multi-detector and SPECT cameras, PET and PET/CT imaging systems and dose calibrators, survey meters and gamma counters. Quality control of individual components is necessary to

  11. Growth of Nuclear Medicine in India

    Directory of Open Access Journals (Sweden)

    A.M. Samuel

    1990-10-01

    Full Text Available The growth of nuclear medicine in India is linked with the developments in our Atomic Energy Programme. Self-sufficiency in radiopharmaceuticals for both in vivo and in vitro use has been largely achieved. The availability of instrumentation facilities in over 90 nuclear medicine centres is indicated. The activities of the Radiation Medicine Centre, a pioneer institute, in the field of diagnosis, therapy and training of personnel are summarised.

  12. Course on internal dosimetry in nuclear medicine

    International Nuclear Information System (INIS)

    This documentation was distributed to the participants in the Course of Internal Dosimetry in Nuclear Medicine organised by the Nuclear Regulatory Authority (ARN) of Argentina and held in Buenos Aires, Argentina, August 9-13, 2004. The course was intended for people from IAEA Member States in the Latin American and Caribbean region, and for professionals and workers in medicine, related with the radiation protection. Spanish and English were the languages of the course. The following subjects were covered: radioprotection of the patient in nuclear medicine; injuries by ionizing radiations; MIRD methodology; radiation dose assessment in nuclear medicine; small scale and microdosimetry; bone and marrow dose modelling; medical internal dose calculations; SPECT and image reconstruction; principles of the gamma camera; scattering and attenuation correction in SPECT; tomography in nuclear medicine

  13. Progress in renal nuclear medicine

    International Nuclear Information System (INIS)

    Progress in nuclear nephrology has come through an understanding of two specific pharmacological interventions: Frusemide and Captopril. Obstruction to outflow may be defined as an increased resistance to outflow above normal. This is usually associated with dilatation of the outflow tract. The obstructing uropathy cannot usually be distinguished from a dilated baggy unobstructive pelvis by examination of the renal images nor the renal activity time curve. In this situation a diuretic renography test with frusemid and calculation of outflow efficiency is very helpful. Captopril intervention was introduced as a form of stress test for the kidney and is able to improve the specificity of the distinction between Essential and Renovascular Hypertension. The typical features therefore are a delayed peak to the renogram, an impaired second phase, a series of images showing a delay in the time for activity to appear in the pelvis, and a prolongation of the mean parenchymal transit time. A study is also a good predictor of the presence of functionally significant restenosis if the patient is followed serially. In conclusion, intervention in renal nuclear medicine is becoming part of standard practice. The substitution of time based measurements for count based measurements should be the trend for the future. (author)

  14. Emerging applications of radioisotopes in nuclear medicine

    International Nuclear Information System (INIS)

    Advances in the domain of radioisotopes and radiopharmaceuticals has been very noteworthy over the past decade and played a major role in enhancing the Nuclear Medicine practice. A number of them have been employed in the day to day clinical practice and have benefited a large number of patients. For the purpose of systematic discussion, we shall classify into two major heads A. Recent advances in clinical applications of traditional radiotracers. B. Newer Radiopharmaceuticals and their applications. The latter could be further subdivided in to the following: (a) Diagnostic (includes i. PET radiopharmaceuticals and ii. Non-PET radiopharmaceuticals for conventional gamma camera imaging) and (b) Therapeutic advances. In the present communication, we shall explore the major developments emphasizing the country perspective

  15. Graduate Program Organization in Clinical Veterinary Medicine.

    Science.gov (United States)

    Horne, R. D.

    1979-01-01

    Graduate training in clinical veterinary medicine is discussed. The options available to the student and problems that must be dealt with are presented, along with the requirements to accomplish a finely structured program that satisfies the needs of both the trainee and clinical veterinary medicine. (Author/MLW)

  16. Experience with Nuclear Medicine Information System

    Directory of Open Access Journals (Sweden)

    Bilge Volkan-Salanci

    2012-12-01

    Full Text Available Objective: Radiology information system (RIS is basically evolved for the need of radiologists and ignores the vital steps needed for a proper work flow of Nuclear Medicine Department. Moreover, CT/MRI oriented classical PACS systems are far from satisfying Nuclear Physicians like storing dynamic data for reprocessing and quantitative analysis of colored images. Our purpose was to develop a workflow based Nuclear Medicine Information System (NMIS that fulfills the needs of Nuclear Medicine Department and its integration to hospital PACS system. Material and Methods: Workflow in NMIS uses HL7 (health level seven and steps include, patient scheduling and retrieving information from HIS (hospital information system, radiopharmacy, acquisition, digital reporting and approval of the reports using Nuclear Medicine specific diagnostic codes. Images and dynamic data from cameras of are sent to and retrieved from PACS system (Corttex© for reprocessing and quantitative analysis. Results: NMIS has additional functions to the RIS such as radiopharmaceutical management program which includes stock recording of both radioactive and non-radioactive substances, calculation of the radiopharmaceutical dose for individual patient according to body weight and maximum permissible activity, and calculation of radioactivity left per unit volume for each radionuclide according their half lives. Patient scheduling and gamma camera patient work list settings were arranged according to specific Nuclear Medicine procedures. Nuclear Medicine images and reports can be retrieved and viewed from HIS. Conclusion: NMIS provides functionality to standard RIS and PACS system according to the needs of Nuclear Medicine. (MIRT 2012;21:97-102

  17. Tomography in nuclear medicine. Proceedings of an international symposium

    International Nuclear Information System (INIS)

    Single photon emission computed tomography (SPECT) is currently being used universally in clinical practice, while positron emission tomography (PET), originally developed as a technique for research, has also gradually moved from the research laboratory to the clinical environment. However, there are significant differences in nuclear medicine capabilities, especially in tomography, between developed and developing countries. The present status and future prospects of nuclear medicine tomography were the main topics of discussion at this latest international symposium, organized by the IAEA in co-operation with the World Health Organization and held in Vienna from 21 to 25 August 1995. The purpose of the meeting was to share experience and information on new developments and clinical applications of two promising tomographic techniques: SPECT and PET. Eight invited papers and 34 regular papers from 23 countries were presented. In addition, there was a panel discussion on the future and direction of tomography in nuclear medicine for developing countries. Refs, figs, tabs

  18. IAEA support to medical physics in nuclear medicine.

    Science.gov (United States)

    Meghzifene, Ahmed; Sgouros, George

    2013-05-01

    Through its programmatic efforts and its publications, the International Atomic Energy Agency (IAEA) has helped define the role and responsibilities of the nuclear medicine physicist in the practice of nuclear medicine. This paper describes the initiatives that the IAEA has undertaken to support medical physics in nuclear medicine. In 1984, the IAEA provided guidance on how to ensure that the equipment used for detecting, imaging, and quantifying radioactivity is functioning properly (Technical Document [TECDOC]-137, "Quality Control of Nuclear Medicine Instruments"). An updated version of IAEA-TECDOC-137 was issued in 1991 as IAEA-TECDOC-602, and this included new chapters on scanner-computer systems and single-photon emission computed tomography systems. Nuclear medicine physics was introduced as a part of a project on radiation imaging and radioactivity measurements in the 2002-2003 IAEA biennium program in Dosimetry and Medical Radiation Physics. Ten years later, IAEA activities in this field have expanded to cover quality assurance (QA) and quality control (QC) of nuclear medicine equipment, education and clinical training, professional recognition of the role of medical physicists in nuclear medicine physics, and finally, the coordination of research and development activities in internal dosimetry. As a result of these activities, the IAEA has received numerous requests to support the development and implementation of QA or QC programs for radioactivity measurements in nuclear medicine in many Member States. During the last 5 years, support was provided to 20 Member States through the IAEA's technical cooperation programme. The IAEA has also supported education and clinical training of medical physicists. This type of support has been essential for the development and expansion of the Medical Physics profession, especially in low- and middle-income countries. The need for basic as well as specialized clinical training in medical physics was identified as a

  19. E-learning for Nuclear Medicine

    International Nuclear Information System (INIS)

    The E-Learning in Nuclear Medicine was developed by the Asian School of Nuclear Medicine (ASNM) through the TC regional project, RAS/0/047 to respond to the need for continuing education of physicians, technologists and other allied professionals working in Nuclear Medicine. ASNM is the collaborating member of the Asian Network for Education in Nuclear Technology (ANENT) and is involved in some educational activities of the IAEA. Ten various cases on different types of organ-system were collected from nine member countries (Bangladesh, India, Indonesia, Japan, Republic of Korea, Malaysia, Pakistan, the Philippines, and Thailand). About 100 cases covered the following organ-systems: Oncology, Cardiology, Neurology, Gastroenterology/Hepatobiliary, Pulmonary, Endocrinology, Pediatrics, Nephrology/Urology, Infection, Muskulo-skeletal, Ophthalmology. Radiotherapy, dosimetry and nuclear medicine diagnostic techniques including PET and SPECT as well as labelling of tracer and application of radiopharmals are covered in the training modules

  20. Nuclear medicine: the Philippine Heart Center experience

    International Nuclear Information System (INIS)

    The following is a report of a three (3) months on-the-job training in Nuclear Medicine at the Nuclear Medicine Department of the Philippine Heart Center. The hospital has current generation nuclear medicine instruments with data processor and is capable of a full range of in vivo and in vitro procedures. Gamma camera is the principal instrument for imaging in nuclear medicine used in the Philippine Heart Center. Thyroid scanning procedure is being performed with these instruments. Also the cardiovascular procedures, the pulmonary, skeletal, renal and hepatobiliary procedures were being performed with the use of gamma camera. Special emphasis is on nuclear cardiology since the PHC attends primarily to cardiovascular patients. (auth.)

  1. Nuclear medicine training and practice in Poland

    Energy Technology Data Exchange (ETDEWEB)

    Teresinska, Anna [Institute of Cardiology, Department of Nuclear Medicine, Warsaw (Poland); Birkenfeld, Bozena [Pomeranian Medical University, Department of Nuclear Medicine, Szczecin (Poland); Krolicki, Leszek [Warsaw Medical University, Department of Nuclear Medicine, Warsaw (Poland); Dziuk, Miroslaw [Military Institute of Medicine, Department of Nuclear Medicine, Warsaw (Poland)

    2014-10-15

    In Poland, nuclear medicine (NM) has been an independent specialty since 1988. At the end of 2013, the syllabus for postgraduate specialization in NM has been modified to be in close accordance with the syllabus approved by the European Union of Medical Specialists and is expected to be enforced before the end of 2014. The National Consultant in Nuclear Medicine is responsible for the specialization program in NM. The Medical Center of Postgraduate Training is the administrative body which accepts the specialization programs, supervises the training, organizes the examinations, and awards the specialist title. Specialization in NM for physicians lasts for five years. It consists of 36 months of training in a native nuclear medicine department, 12 months of internship in radiology, 3 months in cardiology, 3 months in endocrinology, 3 months in oncology, and 3 months in two other departments of NM. If a NM trainee is a specialist of a clinical discipline and/or is after a long residency in NM departments, the specialization in NM can be shortened to three years. During the training, there are obligatory courses to be attended which include the elements of anatomy imaging in USG, CT, and MR. Currently, there are about 170 active NM specialists working for 38.5 million inhabitants in Poland. For other professionals working in NM departments, it is possible to get the title of a medical physics specialist after completing 3.5 years of training (for those with a master's in physics, technical physics or biomedical engineering) or the title of a radiopharmacy specialist after completing 3 years of training (for those with a master's in chemistry or biology). At present, the specialization program in NM for nurses is being developed by the Medical Centre of Postgraduate Education. Continuing education and professional development are obligatory for all physicians and governed by the Polish Medical Chamber. The Polish Society of Nuclear Medicine (PTMN) organizes

  2. Nuclear medicine training and practice in Poland

    International Nuclear Information System (INIS)

    In Poland, nuclear medicine (NM) has been an independent specialty since 1988. At the end of 2013, the syllabus for postgraduate specialization in NM has been modified to be in close accordance with the syllabus approved by the European Union of Medical Specialists and is expected to be enforced before the end of 2014. The National Consultant in Nuclear Medicine is responsible for the specialization program in NM. The Medical Center of Postgraduate Training is the administrative body which accepts the specialization programs, supervises the training, organizes the examinations, and awards the specialist title. Specialization in NM for physicians lasts for five years. It consists of 36 months of training in a native nuclear medicine department, 12 months of internship in radiology, 3 months in cardiology, 3 months in endocrinology, 3 months in oncology, and 3 months in two other departments of NM. If a NM trainee is a specialist of a clinical discipline and/or is after a long residency in NM departments, the specialization in NM can be shortened to three years. During the training, there are obligatory courses to be attended which include the elements of anatomy imaging in USG, CT, and MR. Currently, there are about 170 active NM specialists working for 38.5 million inhabitants in Poland. For other professionals working in NM departments, it is possible to get the title of a medical physics specialist after completing 3.5 years of training (for those with a master's in physics, technical physics or biomedical engineering) or the title of a radiopharmacy specialist after completing 3 years of training (for those with a master's in chemistry or biology). At present, the specialization program in NM for nurses is being developed by the Medical Centre of Postgraduate Education. Continuing education and professional development are obligatory for all physicians and governed by the Polish Medical Chamber. The Polish Society of Nuclear Medicine (PTMN) organizes regular

  3. Diagnostic nuclear medicine. 2. rev. ed.

    Energy Technology Data Exchange (ETDEWEB)

    Schiepers, C. (ed.) [UCLA David Geffen School of Medicine, Los Angeles, CA, (United States). Dept. of Molecular and Medical Pharmacology

    2006-07-01

    The field of nuclear medicine is undergoing rapid expansion, and is evolving into diagnostic molecular imaging. During recent years, dual-modality imaging with PET/CT has gained acceptance and this is currently the fastest-growing technique for oncological imaging applications. The glucose analogue FDG has held its place in diagnostic oncology, assessment of myocardial viability and diagnosis of neuro-degenerative disorders. Peptides have become even more important as imaging agents. The accuracy of hepatobiliary scintigraphy has been enhanced by cholecystokinin. The use of ACE inhibitors in the evaluation of renovascular hypertension has become the standard in renography. New instrumentation has led to faster scanners, and computer development to better image processing software. Automatic processing is more common, and standardization of protocols can be accomplished easily. The field of gene imaging has progressed, although routine clinical applications are not yet available. The present text, supplemented with many detailed and informative illustrations, represents an adjunct to the standard knowledge of diagnostic nuclear medicine and provides both the student and the professional with an overview of developments during the past decade. (orig.)

  4. Radiation dose assessment in nuclear medicine

    International Nuclear Information System (INIS)

    Radionuclides are used in nuclear medicine in a variety of diagnostic and therapeutic procedures. Recently, interest has grown in therapeutic agents for a number of applications in nuclear medicine. Internal dose models and methods have been in use for many years, are well established and can give radiation doses to stylized models representing reference individuals. Kinetic analyses need to be carefully planned, and dose conversion factors should be chosen that are most similar to the subject in question and that can then be tailored to be more patient specific. Such calculations, however, are currently not relevant in patient management in internal emitter therapy, as they are not sufficiently accurate or detailed to guide clinical decision making. Great strides are being made at many centres regarding the use of patient image data to construct individualized voxel based models for more detailed and patient specific dose calculations.These recent advances make it likely that the relevance will soon change to be more similar to that of external beam treatment planning. (author)

  5. New horizons in radiopharmaceuticals. Nuclear Medicine may concentrate on its unique strengths if it is to continue to prove clinically useful and survive into the new century

    International Nuclear Information System (INIS)

    People undertake research in radiopharmacy for many different reasons. Those that work in the pharmaceutical industry follow defined development strategies with the ultimate aim of registering a new product and generating money for the company. This article is concerned mostly with the work that is conducted in academic institutions where intellectual, rather than financial, pursuits are the norm. The most successful research projects are normally those that seek to solve a particular clinical problem. This provides the necessary focus to the project as well as giving the researchers the ultimate satisfaction of seeing their endeavours put to good use. With the improvements in competing modalities - such as spiral CT, Doppler echo and spectroscopic MRI for determination of locality and perfusion of disease - there is an increasing need for Nuclear Medicine to concentrate on its unique ability to perform functional assessment of tissues and, in particular, to try and assess intracellular as well as extracellular changes. Recent developments in the field of targeted radionuclide therapy have also given a fresh impetus to work in this area. This review presents the authors' personal view of some of the most promising areas of current radiopharmaceutical research

  6. Maintenance of nuclear medicine instruments

    International Nuclear Information System (INIS)

    Maintenance of instruments is generally of two kinds: (a) corrective maintenance, on a non-scheduled basis, to restore equipment to a functional status by repairs; (b) preventive maintenance, to keep equipment in a specified functional condition by providing systematic inspection, quality control, detection and correction of early malfunctions. Most of the instruments used in nuclear medicine are rather complex systems built from mechanical, electrical and electronic parts. Any one of these components is liable to fail at some time or other. Repair could be done only by a specialist who is able to evaluate the condition of the various parts ranging from cables to connectors, from scintillators to photomultipliers, from microprocessors to microswitches. The knowledge of the intricacies of the various electronic components required for their repairs is quite wide and varied. The electronics industry turns out more and more multi-purpose chips which can carry out the functions of many parts used in the instruments of the earlier generation. This provides protection against unauthorized copying of the circuits but it serves another purpose as well of inhibiting repairs by non-factory personnel. These trends of the instrument design should be taken into consideration when a policy has to be developed for the repairs of the hospital based equipment

  7. A sports medicine clinic in the community.

    OpenAIRE

    Davison, J.; Ryan, M. P.

    1988-01-01

    We report the attempt to set up a mini sports medicine clinic in a health centre resourced by a Department of Community Medicine. The type of problems seen are similar to those reported by other clinics. On the results of this pilot project, we believe it would be possible to establish similar clinics in health centres elsewhere in the United Kingdom. The National Health Service resources required are minimal, but the benefits to local communities are considerable.

  8. Quality control of nuclear medicine instruments, 1991

    International Nuclear Information System (INIS)

    This document gives detailed guidance on the quality control of various instruments used in nuclear medicine. A first preliminary document was drawn up in 1979. A revised and extended version, incorporating recommended procedures, test schedules and protocols was prepared in 1982. The first edition of 'Quality Control of Nuclear Medicine Instruments', IAEA-TECDOC-317, was printed in late 1984. Recent advances in the field of nuclear medicine imaging made it necessary to add a chapter on Camera-Computer Systems and another on SPECT Systems

  9. Quality control of nuclear medicine instruments 1991

    International Nuclear Information System (INIS)

    This document gives detailed guidance on the quality control of various instruments used in nuclear medicine. A first preliminary document was drawn up in 1979. A revised and extended version, incorporating recommended procedures, test schedules and protocols was prepared in 1982. The first edition of ''Quality Control of Nuclear Medicine Instruments'', IAEA-TECDOC-317, was printed in late 1984. Recent advances in the field of nuclear medicine imaging made it necessary to add a chapter on Camera-Computer Systems and another on SPECT Systems. Figs and tabs

  10. Physics and radiobiology of nuclear medicine

    CERN Document Server

    Saha, Gopal B

    2010-01-01

    From a distinguished author comes this new edition for technologists, practitioners, residents, and students in radiology and nuclear medicine. Encompassing major topics in nuclear medicine from the basic physics of radioactive decay to instrumentation and radiobiology, it is an ideal review for Board and Registry examinations. The material is well organized and written with clarity. The book is supplemented with tables and illustrations throughout. It provides a quick reference book that is concise but comprehensive, and offers a complete discussion of topics for the nuclear medicine and radi

  11. Nuclear medicine applications: Summary of Panel 4

    Energy Technology Data Exchange (ETDEWEB)

    Wolf, A.P.

    1988-01-01

    Nuclear medicine is currently facing a desperate shortage of organic and inorganic chemists and nuclear pharmacists who also have advanced training in nuclear and radiochemistry. Ironically, this shortfall is occurring in the face of rapid growth and technological advances which have made the practice of nuclear medicine an integral part of the modern health care system. This shortage threatens to limit the availability of radiopharmaceuticals required in routine hospital procedures and to impede the development of new diagnostic and therapeutic agents. To redress this need and prevent a similar shortfall in the future, this panel recommends immediate action and a long-term commitment to the following: educating the public on the benefits of nuclear medicine; informing undergraduate and graduate chemistry students about career opportunities in nuclear medicine; offering upper level courses in nuclear and radiochemistry (including laboratory) in universities; establishing training centers and fellowships at the postgraduate level for specialized education in the aspects of nuclear and radiochemistry required by the nuclear medicine profession. 1 tab.

  12. Nuclear medicine applications: Summary of Panel 4

    International Nuclear Information System (INIS)

    Nuclear medicine is currently facing a desperate shortage of organic and inorganic chemists and nuclear pharmacists who also have advanced training in nuclear and radiochemistry. Ironically, this shortfall is occurring in the face of rapid growth and technological advances which have made the practice of nuclear medicine an integral part of the modern health care system. This shortage threatens to limit the availability of radiopharmaceuticals required in routine hospital procedures and to impede the development of new diagnostic and therapeutic agents. To redress this need and prevent a similar shortfall in the future, this panel recommends immediate action and a long-term commitment to the following: educating the public on the benefits of nuclear medicine; informing undergraduate and graduate chemistry students about career opportunities in nuclear medicine; offering upper level courses in nuclear and radiochemistry (including laboratory) in universities; establishing training centers and fellowships at the postgraduate level for specialized education in the aspects of nuclear and radiochemistry required by the nuclear medicine profession. 1 tab

  13. Clinical forensic medicine examination of trafficked victims

    Directory of Open Access Journals (Sweden)

    Alempijević Đorđe M.

    2004-01-01

    Full Text Available In this paper certain explanations of health related aspects of human trafficking are discussed together with responsibilities of health care providers to the victims of trafficking. Clinical forensic medicine is outlined, and its role in obtaining of medical evidence has been discussed. Special remarks are made on the application of clinical forensic medicine skills in assessment of victims of human trafficking. Protocol for clinical forensic examination of the victims of human trafficking, which has been developed in the Institute of Forensic Medicine in Belgrade, has been discussed in details.

  14. Hand Dose in Nuclear Medicine Staff Members

    International Nuclear Information System (INIS)

    Measurement of the hand dose during preparation and injection of radiopharmaceuticals is useful in the assessment of the extremity doses received by nuclear medicine personnel. Hand radiation doses to the occupational workers that handling 99mTc-labeled compounds, 131I for diagnostic in nuclear medicine were measured by thermoluminescence dosimetry. A convenient method is to use a TLD ring dosimeter for measuring doses of the diagnostic units of different nuclear medicine facilities . Their doses were reported in millisieverts that accumulated in 4 weeks. The radiation doses to the hands of nuclear medicine staff at the hospitals under study were measured. The maximum expected annual dose to the extremities appeared to be less than the annual limit (500 mSv/y) because all of these workers are on rotation and do not constantly handle radioactivity throughout the year

  15. Development of PACS in nuclear medicine

    International Nuclear Information System (INIS)

    The in-house development of Picture Archiving and Communication System (PACS) in Nuclear Medicine is cost-effective. It provides various expansion options in transfer, processing, archival and retrieval of images according to the convenience of the department

  16. A DICOM based PACS for nuclear medicine

    International Nuclear Information System (INIS)

    The installation of a radiology information system (RIS) connected to a hospital information system (HIS) and a picture archiving and communications system (PACS) seems mandatory for a nuclear medicine department in order to guarantee a high patient throughput. With these systems a fast transmission of reports, images to the in- and out-patients' wards and private practitioners is realized. Therefore, since April 2000, at the department of nuclear medicine of the university of Wuerzburg a completely DICOM based PACS has been implemented in addition to the RIS. With this system a DICOM based workflow is realized throughout the department of nuclear medicine for reporting and archiving. The PACS is connected to six gamma-cameras, a PET scanner, a bone densitometry system and an ultrasound device. The volume of image data archived per month is 4 GByte. Patient demographics are provided to the modalities via DICOM-Worklist. With these PACS components a department specific archive purely based on DICOM can be realized. During the installation process problems occurred mainly because of the complex DICOM standard for nuclear medicine. Related to that is the problem that most of the software implementations still contain bugs or are not adapted to the needs of a nuclear medicine department (particularly for PET). A communication software for the distribution of nuclear medicine reports and images based on techniques used for the worldwide web is currently tested. (orig.)

  17. Nuclear medicine and how it developed

    International Nuclear Information System (INIS)

    Nuclear medicine is the science of using nuclear properties of matter in medicine. The elemental particles like protons and neutrons are in a particular arrangement or constellation to each other in the nucleus of an atom. If this constellation is disturbed by changing their numbers or position to each other in a cyclotron or a nuclear reactor, the nucleus of such an atom will try to come back to a stable constellation by giving up or emitting energy in form of radiations. This is the basic nuclear property of matter. This chapter also briefly discussed on the development of nuclear medicine since the discovery of radium by Madam Curie and utilization of radioisotopes for the study of plant physiology by George von Hevesy. (author)

  18. General situation of the 8th world federation of nuclear medicine and biology meeting

    International Nuclear Information System (INIS)

    The general situation of the 8th World Federation of Nuclear Medicine and Biology Meeting is described here. The main contents involve recently investigated achievements relating closely to the basic or experimental and clinical nuclear medicine, and new development of novel radiopharmaceuticals and nuclear instruments

  19. Recent Advances in Nuclear Medicine Imaging Instrumentation

    International Nuclear Information System (INIS)

    This review introduces advances in clinical and pre-clinical single photon emission computed tomography (SPECT) and positron emission tomography (PET) providing noninvasive functional images of biological processes. Development of new collimation techniques such as multi-pinhole and slit-slat collimators permits the improvement of system spatial resolution and sensitivity of SPECT. Application specific SPECT systems using smaller and compact solid-state detector have been customized for myocardial perfusion imaging with higher performance. Combined SPECT/CT providing improved diagnostic and functional capabilities has been introduced. Advances in PET and CT instrumentation have been incorporated in the PET/CT design that provide the metabolic information from PET superimposed on the anatomic information from CT. Improvements in the sensitivity of PET have achieved by the fully 3D acquisition with no septa and the extension of axial field-of-view. With the development of faster scintillation crystals and electronics, time-of-flight (TOF) PET is now commercially available allowing the increase in the signal-to-noise ratio by incorporation of TOF information into the PET reconstruction process. Hybrid PET/SPECT/CT systems has become commercially available for molecular imaging in small animal models. The pre-clinical systems have improved spatial resolution using depth-of-interaction measurement and new collimators. The recent works on solid state detector and dual modality nuclear medicine instrumentations incorporating MRI and optical images will also be discussed

  20. A Training Manual for Nuclear Medicine Technologists.

    Science.gov (United States)

    Simmons, Guy H.; Alexander, George W.

    This manual was prepared for a training program in Nuclear Medicine Technology at the University of Cincinnati. Instructional materials for students enrolled in these courses in the training program include: Nuclear Physics and Instrumentation, Radionuclide Measurements, Radiation Protection, and Tracer Methodology and Radiopharmaceuticals. (CS)

  1. VIIth international symposium on nuclear medicine

    International Nuclear Information System (INIS)

    The conference proceedings contain abstracts of 100 presented papers, mainly dealing with radioimmunoassays, radiopharmaceuticals, scintiscanning, computer tomography, radionuclide lymphography, ventriculography, angiography, nuclear cardiology, liquid scintillator techniques, radioisotope generators, radiospirometry and various uses of labelled compounds and tracer techniques in nuclear medicine. (M.D.)

  2. Analysis of renal nuclear medicine images

    International Nuclear Information System (INIS)

    Nuclear medicine imaging of the renal system involves producing time-sequential images showing the distribution of a radiopharmaceutical in the renal system. Producing numerical and graphical data from nuclear medicine studies requires defining regions of interest (ROIs) around various organs within the field of view, such as the left kidney, right kidney and bladder. Automating this process has several advantages: a saving of a clinician's time; enhanced objectivity and reproducibility. This thesis describes the design, implementation and assessment of an automatic ROI generation system. The performance of the system described in this work is assessed by comparing the results to those obtained using manual techniques. Since nuclear medicine images are inherently noisy, the sequence of images is reconstructed using the first few components of a principal components analysis in order to reduce the noise in the images. An image of the summed reconstructed sequence is then formed. This summed image is segmented by using an edge co-occurrence matrix as a feature space for simultaneously classifying regions and locating boundaries. Two methods for assigning the regions of a segmented image to organ class labels are assessed. The first method is based on using Dempster-Shafer theory to combine uncertain evidence from several sources into a single evidence; the second method makes use of a neural network classifier. The use of each technique in classifying the regions of a segmented image are assessed in separate experiments using 40 real patient-studies. A comparative assessment of the two techniques shows that the neural network produces more accurate region labels for the kidneys. The optimum neural system is determined experimentally. Results indicate that combining temporal and spatial information with a priori clinical knowledge produces reasonable ROIs. Consistency in the neural network assignment of regions is enhanced by taking account of the contextual

  3. Festschrift. The Institute of Nuclear Medicine. 50 years

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    The Institute of Nuclear Medicine, founded in 1961, celebrates with this Festschrift, its Golden Jubilee. It has been a remarkable 50 years of progress of the radionuclide tracer methodology. From initial, physiology based experimentation, a full independent medical discipline evolved, and with it, a comprehensive clinical service. Diagnosis and Treatment with radiotracers have established the basis for Nuclear Medicine. Technological advances have permeated the field like none other, its multidisciplinary character and its translational research are embedded in the history of the Institute and its success. Recent and latest advances in the field promise a future as bright as has been witnessed and documented in the last 50 years.

  4. Research advancements and applications of carboranes in nuclear medicinal chemistry

    International Nuclear Information System (INIS)

    Because of their uniquely high thermal and chemical stabilities, carboranes have become a subject of study with high interest in the chemistry of supra molecules, catalysts and radiopharmaceuticals. In recent years, the role of carboranes in nuclear medicinal chemistry has been diversified, from the traditional use in boron neutron capture therapy (BNCT), to the clinical applications in molecular radio imaging and therapy. This paper provides an overview of the synthesis and characterization of carboranes and their applications in nuclear medicinal chemistry, with highlights of recent key advancements in the re- search areas of BNCT and radio imaging. (authors)

  5. The Bottom Line Medicine Clinic.

    OpenAIRE

    Gepner, G. J.

    1991-01-01

    The financial experience of an actual medical practice was used to develop a spreadsheet model of the business of medicine. The model is designed to provide reasonably accurate predictions of the financial outcome of business decisions affecting the practice. It has been used very successfully to teach practice management to senior residents in Family Practice training at the University of Minnesota. Students are placed in the role of a managing partner presented with a financially ailing pra...

  6. Gene therapy in clinical medicine

    OpenAIRE

    Selkirk, S

    2004-01-01

    Although the field of gene therapy has experienced significant setbacks and limited success, it is one of the most promising and active research fields in medicine. Interest in this therapeutic modality is based on the potential for treatment and cure of some of the most malignant and devastating diseases affecting humans. Over the next decade, the relevance of gene therapy to medical practices will increase and it will become important for physicians to understand the basic principles and st...

  7. Nuclear medicine development in the southern urals

    International Nuclear Information System (INIS)

    The last 25 years results of organization work at Nuclear Medicine cluster in the Southern Urals are presented. The main purpose of the project was - to create one of the largest Russian platforms for the development and application of nuclear technology. A successive branched system of radiopharmaceutical production and radiopharmaceuticals consumers effectively operate in the region, and is provided by prepared staff and is able to provide high-tech care for cancer patients using nuclear program in the field of health care

  8. Dynamic functional studies in nuclear medicine in developing countries

    International Nuclear Information System (INIS)

    The Proceedings document some of the trials and tribulations involved in setting up nuclear medicine facilities in general and specifically as regards nuclear medicine applications for the diagnosis of the diseases prevalent in the less developed countries. Most of the 51 papers deal with various clinical applications of dynamic functional studies. However, there was also a session on quality control of the equipment used, and a panel discussion critically looked at the problems and potential of dynamic studies in developing countries. This book will be of interest and use not only to those practising nuclear medicine in the developing countries, but it may also bring home to users in developed countries how ''more can be done with less''. Refs, figs and tabs

  9. Traceability of radionuclide calibrators measurements in nuclear medicine

    International Nuclear Information System (INIS)

    In nuclear medicine, the administered doses of the radiopharmaceutical are expressed through the amount of radioactivity contained in the drug. The measurement of this activity, performed using a radionuclide calibrator, is of the utmost importance to guarantee the national and international comparability of clinic results and the radiological safety of the patient. In this paper, the transferring of the becquerel unit to the radionuclide calibrators employed in the nuclear medicine practice in Cuba is detailed. The obtained results with an in situ calibration service, which is based on the direct comparison with standards of the specific measured radionuclides, are presented. Outcomes of international and national measurement comparisons are shown. They validate the uncertainty estimates of the calibration coefficients installed in the instruments for measurements of 99Tcm , 131I and 201Tl, the main gamma emitters that have been used in Cuban nuclear medicine. (author)

  10. The role of nuclear medicine in oncology

    International Nuclear Information System (INIS)

    Nuclear Medicine offers screening methods for oncology such as bone and bone marrow scintigraphy. During the last two decades, special procedures have gained widespread application. This paper is centered around the 'tumor-specific' radiopharmaceuticals. In patients with thyroid cancer, I-131 still plays a significant role. Ga-67 still has its indications in lymphoma, while in other diseases Tl-201 cloride is now the agent of choice. Especially in thyroid cancer, Tl-201 has proved to be a reliable tumor imaging radiopharmaceutical. More recently, Tc-99m MIBI was introduced for tumor imaging. Tc-99m HMPAO may also be used for tumor scintigraphy, especially in brain lesions. In addition, I-123 IMP has successfully been used for imaging malignant melanoma. Another promising field of tumor diagnosis is receptor imaging. In neuroblastoma and malignant pheochromocytoma, I-131/123 mIBG is the radiopharmaceutical of choice and may be considered as a receptor imaging agent also. First clinical results with In-111 octreotide show potentials as somatostatine-receptor radiopharmaceutical in insulinoma, islet cell carcinoma, medullary and lung cancer, while I-123 estradiol needs some improvement until it may be recommended as diagnostic tool in breast cancer. Since 1978, radiolabeled poly- or monoclonal tumor antibodies and their fragments have gained widespread application. Especially the Tc-99m 225.28S melanoma antibody, I-131 or Tc-99m CEA and In-111/I-131 labeled OC-125 antibodies have proven to be of clinical significance in melanoma, colorectal and ovarian cancer. (author)

  11. The contribution of Medical Physics to Nuclear Medicine: looking back - a physicist’s perspective

    OpenAIRE

    Hutton, Brian F

    2014-01-01

    Background This paper is the first in a series of invited perspectives by four pioneers of Nuclear Medicine imaging and physics. A medical physicist and a Nuclear Medicine clinical specialist each take a backward look and a forward look at the contributions of Medical Physics to Nuclear Medicine. Discussion Contributions of Medical Physics are presented from the early discovery of radioactivity, development of first imaging devices, computers and emission tomography to recent development of h...

  12. Quality control of nuclear medicine equipment

    International Nuclear Information System (INIS)

    In order to determine functional status and integrity of installations and equipment used in nuclear medicine in everyday medical practice or in research studies, it is important to maintain and implement quality control program. For this type of installation are required high standards, particularly with regard to qualitative and quantitative analysis of the image, and volume measurements in diagnosis and dosimetry. Given the precarious situation of the economy in transition, nuclear medicine departments in the republic, now, can not be always of service contracts with providers of facilities and equipment for routine maintenance and periodic calibration. Therefore, in this article are at some of the quality control procedures should be performed usually by engineers and physicists from the department of nuclear medicine. (authors)

  13. Basics of radiobiology and nuclear medicine

    International Nuclear Information System (INIS)

    The authors successively reveal the topics of the biological impact of radiation (radiobiology) and the diagnostic and the therapeutic application of radiopharmaceuticals (nuclear medicine). Data on the influence of radiation on subcellular, cellular, tissue and organ level are given, on early and late radiation changes, as well. Indication for the application of the different radionuclide methods in the diagnosis of the diseases in the endocrinology, nephrology, cardiology, gastroenterology, haematology of lungs, bones, tumors are pointed out and the main trends of the growing therapeutical use of nuclear medicine are presented. The aim is to teach students the nuclear medicine methods in the complex investigation of the patients, his preliminary preparation and the biological impact of radiation and its risk. Self assessment test for students are proposed and a literature for further reading

  14. Radiopharmaceutical prescription in nuclear medicine departments

    International Nuclear Information System (INIS)

    In France, radiopharmaceutical prescription is often discussed depending to which juridical structure the nuclear medicine department is belonging. According to current regulation, this prescription is an obligation in a department linked to hospital with a pharmacy department inside. But situation remains unclear for independent nuclear medicine departments where physicians are not constrained to prescribe radiopharmaceuticals. However, as radiographers and nurses are only authorized to realize theirs acts in front of a medical prescription, one prescription must be realized. Nowadays, computerized prescription tools have been developed but only for radiopharmaceutical drugs and not for medical acts. In the aim to achieve a safer patient care, the prescription regulation may be applied whatever differences between nuclear medicines departments. (authors)

  15. Exposure from diagnostic nuclear medicine procedures

    International Nuclear Information System (INIS)

    According to our last national study on population exposures from natural and artificial sources of ionizing radiation, 16% of overall annual collective effective dose represent the contribution of diagnostic medical exposures. Of this value, 92% is due to diagnostic X-ray examinations and only 8% arise from diagnostic nuclear medicine procedures. This small contribution to collective dose is mainly the result of their lower frequency compared to that of the X-ray examinations, doses delivered to patients being, on average, ten times higher. The purpose of this review was to reassess the population exposure from in vivo diagnostic nuclear medicine procedures and to evaluate the temporal trends of diagnostic usage of radiopharmaceuticals in Romania. The current survey is the third one conducted in the last decade. As in the previous ones (1990 and 1995), the contribution of the Radiation Hygiene Laboratories Network of the Ministry of Health and Family in collecting data from nuclear medicine departments in hospitals was very important

  16. Management of radioactive waste generated in nuclear medicine; Gestion de los residuos radiactivos generados en medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Lorenz Perez, P.

    2015-07-01

    Nuclear medicine is a clinical specialty in which radioactive material is used in non-encapsulated form, for the diagnosis and treatment of patients. Nuclear medicine involves administering to a patient a radioactive substance, usually liquid, both diagnostic and therapeutic purposes. This process generates solid radioactive waste (syringes, vials, gloves) and liquid (mainly the patient's urine). (Author)

  17. Nuclear Medicine in a developing country

    International Nuclear Information System (INIS)

    Namibia is a country with 1,8 million inhabitants, of whom the majority has limited access to first world facilities. Nevertheless, medical services of high standard are offered. A Nuclear Medicine Department was established at Windhoek Central Hospital in 1982. A nuclear physician, two nuclear medicine radiographers and a nursing sister staff the department. Equipment includes a Siemens Orbiter and an Elscint Apex SPX Helix gamma camera. Radiopharmaceuticals are obtained from suppliers in South Africa. Investigations performed include musculoskeletal, liver, hepatobiliary, thyroid, renal studies, ventilation perfusion lung scans as well as the following Nuclear Cardiology studies: Gated blood pool scans, Tc-99m pyrophosphate hot spot scans, Tl-201 myocardial perfusion studies, Tc-99m MIBI myocardial perfusion studies and Tl-201 rest-redistribution studies. Problems experienced at the Windhoek Nuclear Medicine department include: Lack of funding and high cost of equipment and radiopharmaceuticals, lack of understanding of Nuclear Medicine by the hospital management and health administrators, and difficulties in procuring short-lived radiopharmaceuticals. Furthermore, the absence of company representatives and spare parts in Namibia leads to loss of time whenever equipment needs to be repaired. Working as the only nuclear medicine physician in a country also poses major problems. Careful management of resources and information drives have helped to sustain the Nuclear Medicine service despite economic problems in the country. Installation of a tele-link between the department in Windhoek Hospital and Tygerberg Hospital in South Africa has greatly assisted to overcome the problem of isolation and lack of back up from fellow specialists. The IAEA has equipped both departments with Hermes workstations (Nuclear Diagnostics) and a tele-link is maintained via modem. The current software provided with the Hermes system is ideally suited to processing of data such as gated

  18. Nuclear medicine with its interdependencies

    International Nuclear Information System (INIS)

    Newly developed nuclear methods and measuring techniques in the diagnosis and therapy of diseases of the blood, heart, vessels, thyroid, gastrointestinal tract, kidneys, skeleton and ophthalmological diseases are described. Occupational radiation exposure is briefly discussed. (AJ)

  19. Calibration of nuclear medicine gamma counters

    International Nuclear Information System (INIS)

    In this paper the practical problem of nuclear medicine gamma counters calibration has been solved by using dose calibrators CRC-15R with standard error ±5%. The samples from technetium generators have been measured both by dose calibrators CRC-15R and gamma counter ICN Gamma 3.33 taking into account decay correction. Only the linear part of the curve has practical meaning. The advantage of this procedure satisfies the requirements from international standards: the calibration of sources used for medical exposure be traceable to a standard dosimetry laboratory and radiopharmaceuticals for nuclear medicine procedures be calibrated in terms of activity of the radiopharmaceutical to be administered. (author)

  20. Role of nuclear medicine in dentistry

    Directory of Open Access Journals (Sweden)

    Shazia Mushtaq

    2013-01-01

    Full Text Available Nuclear medicine studies often play a significant role in the diagnosis and treatment of oral and maxillofacial diseases. While not commonly used in everyday dental practice, the dental provider should have a conversational knowledge of these imaging modalities and understand the indications and limitations of these studies. The purpose of this review is to discuss the nuclear medicine studies that have applications in the head and neck region as well as their indications, limitations, and diagnostic conclusions that can be drawn from these studies.

  1. Basic requirements of nuclear medicine services

    International Nuclear Information System (INIS)

    Technological progress in nuclear medicine continues, not always to the immediate advantage of the developing world. The capital expense, operational demands and maintenance requirements of ever more complex equipment, the consequent need for highly trained staff, the necessity to assure regular supplies of costly radioactive materials, all present problems to which compromise or alternative solutions must often be sought. This chapter constitutes an attempt to define the basic requirements for thr practice of nuclear medicine with respect to staff, equipment, accommodation, supplies and supporting services with particular reference to the needs of institutions in developing countries

  2. Training and education in nuclear medicine at the Medical Faculty of the University of Zagreb

    International Nuclear Information System (INIS)

    Training for specialization in nuclear medicine in Yugoslavia includes 12 months of training in departments of clinical medicine and 24 months of training in departments of nuclear medicine. Since 1974 many physicians have passed the specialist examination in Zagreb. A postgraduate study in nuclear medicine began at the Medical Faculty of the University of Zagreb in 1979. It includes four semesters of courses and research on a selected subject leading to the degree of Magister (Master of Science). Most of the training is conducted by the Institute of Nuclear Medicine at the University Hospital, Rebro, in Zagreb, which has the necessary teaching staff, equipment and space. Forty-four students have completed this postgraduate study. Nuclear medicine in a developing country faces several problems. Scarcity of expensive equipment and radiopharmaceuticals calls for modifications of methods, home made products and instrument maintenance. These, mostly economic, factors are given special emphasis during training. Nuclear power generation may solve some of the country's energy problems; therefore, specialists in nuclear medicine must obtain additional knowledge about the medical care and treatment of persons who might be subject to irradiation and contamination in nuclear power plants. Lower economic resources in developing countries require better trained personnel, stressing the need for organized training and education in nuclear medicine. With some support the Institute of Nuclear Medicine will be able to offer various forms of training and education in nuclear medicine for physicians, chemists, physicists, technologists and other personnel from developing countries. (author)

  3. Medicine and clinical skills laboratories

    Directory of Open Access Journals (Sweden)

    Abdulmohsen H Al-Elq

    2007-01-01

    Full Text Available The main objective of the medical curriculum is to provide medical students with knowledge, skills and attitudes required for their practice. A decade ago, the UK Medical Council issued a report called "Tomorrow′s Doctors" [1] which called for the reduction in the factual content of the medical course with the promotion of problem-based and self-dedicated learning. This report was the basis for a move toward an extensive reform of the medical and nursing curricula. The new reformed curricula enhanced the integrated medical teaching and emphasized the teaching and learning of clinical skills. However, there were still concerns about the standards and appropriateness of the skills of new medical graduates. [2] The changes in the teaching and learning methods, the radical changes in the health care delivery and the rapid growth of technology challenged the traditional way of clinical skills development and led to the emergence of clinical skills laboratories (CSLs in the medical education of many medical and nursing schools. With the proliferation of the CSLs, it is important to evaluate and introduce the reader to their applications, bearing in mind the paucity of information on this subject particularly over the last couple of years. This article is based on literature review.

  4. Medicine and clinical skills laboratories.

    Science.gov (United States)

    Al-Elq, Abdulmohsen H

    2007-05-01

    The main objective of the medical curriculum is to provide medical students with knowledge, skills and attitudes required for their practice. A decade ago, the UK Medical Council issued a report called "Tomorrow's Doctors"(1) which called for the reduction in the factual content of the medical course with the promotion of problem-based and self-dedicated learning. This report was the basis for a move toward an extensive reform of the medical and nursing curricula. The new reformed curricula enhanced the integrated medical teaching and emphasized the teaching and learning of clinical skills. However, there were still concerns about the standards and appropriateness of the skills of new medical graduates.(2)The changes in the teaching and learning methods, the radical changes in the health care delivery and the rapid growth of technology challenged the traditional way of clinical skills development and led to the emergence of clinical skills laboratories (CSLs) in the medical education of many medical and nursing schools. With the proliferation of the CSLs, it is important to evaluate and introduce the reader to their applications, bearing in mind the paucity of information on this subject particularly over the last couple of years. This article is based on literature review. PMID:23012147

  5. Training of nuclear medicine technical staff by the Brazilian Society of Nuclear Medicine and Biology

    International Nuclear Information System (INIS)

    Full text: Nuclear medicine was introduced in Brazil in 1949, at the University of Sao Paulo. Despite being a pioneer in South America and the existence of about 280 clinics of this medical specialty in the whole country serving around 185 million inhabitants, there is not any dedicated course forming its technical staff. Another shortcoming lies in the fact that there are not any basic requirements established for these professionals by an official medical or nuclear entity. As result, one can find persons ranging from university graduates (biomedics, radiology technologists, biologists, pharmacists, chemists, physicists, etc.) to secondary school graduates or radiology technicians working in nuclear medicine centres, preparing patients, labelling and injecting radiopharmaceuticals, obtaining images and processing studies. Due to the high heterogeneity of the technical staff and lack of a formal preparation, the Brazilian Society of Nuclear Medicine and Biology (SBBMN) organized during 2004 and 2005 short courses conducted in different regions of Brazil in order to supply organized basic knowledge and practice on: 1. Quality control of 99Mo-99mTc eluates and labelling and checking of dose calibrators 2. Fundamentals of radiation protection, area monitoring and decontamination 3. Quality control of scintillation cameras. Six courses were given during these two years in four cities in the South Eastern region and two in the North Eastern region. The first two topics were delivered during one weekend and the participants were presented with a lecture in the morning and, in the afternoon, a hands-on practice on the same subject. As QC of eluates and labelling and checking of dose calibrators were less practised in most clinics, this was the first time that the majority of the participants performed these activities. In one course, offered during a national congress, all three topics were included and the practical part was replaced by many examples from routine

  6. A literature review of the cost-effectiveness of nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine is a medical speciality that uses tiny quantities of radioactivity to produce diagnostic images. It also has a role in therapy for some thyroid diseases and certain tumours. Surveys have shown that nuclear medicine procedures are used significantly less in the UK than in many other countries in Europe. One reason may be that there is inadequate information about the clinical utility of these techniques, particularly their cost-effectiveness in clinical management. To establish what evidence was currently available about the cost-effectiveness of nuclear medicine, the British Nuclear Medicine Society commissioned a worldwide literature review in diseases of the heart, kidney, lung, bone, brain, bowel and thyroid. This volume summarises the findings of the independent study and gives details of the background, clinical utility and limitations of the different nuclear medicine procedures used in the diagnosis and treatment of each disease reviewed. (author)

  7. Pathway to the contemporary innovations in nuclear medicine

    International Nuclear Information System (INIS)

    Full text: Introduction: A brief overview of the long road of fundamental discoveries, innovations and their improvement and development of modern clinical nuclear medicine from the discovery of X- rays by Wilhelm Conrad Roentgen (1895), the phenomenon of radioactivity by Antoine Henry Becquerel (1896), the natural radioactivity and discovering of radium and polonium by Marie and Pierre Curie (1897) discovering of radioactive decay (alpha, beta particles and gamma photons) and the term 'half-life' by Ernest Rutherford (1900), discovering of artificial radioactivity with the possibility of obtaining new radionuclides by Irena and Frederick Joliot-Curie (1932 ). What you will learn: Important place in nuclear medicine radiochemistry is discovering of routine production and clinical use of the most appropriate radiopharmaceuticals (RFs) specific for the given diagnostic and therapy. Such are radioactive Gold, Mercury, Selenium, radionuclides of Iodine (131I-NaI, 123I), RFs marked with 99mTc, 111In, 67Ga, more widely applicable short-lived positron emitters 18F, 11C 15O, 13N, 68Ga and their radiopharmaceutical forms for diagnostic. For metabolic radionuclide therapy for many years 198Au has been used in omentum carcinose, and 32P for bone metastases, polycythemia vera and 131I-NaI as a gold standard in treatment of differentiated thyroid carcinoma and some benign hyperfunctional conditions. Today 89Sr, 153Sm, 186Re are applied for pain control in metastatic bone disease. 90Y-ibritumomab tiuxetan (Zevalin) and 131I-tositumomab (Bexxar) are used for specific treatment of lymphomas. Discussion: Starting with the first diagnostic nuclear medicine study performed by Hermann Blumgart and Otto Jens in 1926, passing through the first static display of RFs biodistribution in 50s and faster static and dynamic images of the proposed by Hal Anger gamma camera and PET imaging by Gordon Brownell, nuclear medicine metabolic images improved with more precise functional and structural

  8. The positron camera in nuclear medicine

    International Nuclear Information System (INIS)

    Positron emission tomography is making headway in health care delivery. With improvements in instrumentation and physiologic tracers and with the development of hospital-based compact cyclotrons, 'physiopathologic tomography' is around the corner in nuclear medicine. This paper is a brief review of positron emission tomography: instrumentation and applications

  9. VIIIth international symposium on nuclear medicine

    International Nuclear Information System (INIS)

    The conference proceedings contain 92 abstracts of submitted papers dealing with various applications of radioisotopes in diagnosis and therapy. The papers were devoted to scintiscanning, radioimmunoassay, tomography, the applications of nuclear magnetic resonance and electron microscopy in different branches - oncology, cardiology, neurology, histology, gynecology, internal medicine, etc. (M.D.)

  10. Dosimetry in Nuclear Medicine Diagnosis and Therapy

    Science.gov (United States)

    Noßke, D.; Mattsson, S.; Johansson, L.

    This document is part of Subvolume A 'Fundamentals and Data in Radiobiology, Radiation Biophysics, Dosimetry and Medical Radiological Protection' of Volume 7 'Medical Radiological Physics' of Landolt-Börnstein - Group VIII 'Advanced Materials and Technologies'. It contains the Section '4.7 Necessity of Patient-Specific Dose Planning in Radionuclide Therapy' of the Chapter '4 Dosimetry in Nuclear Medicine Diagnosis and Therapy'.

  11. Abstracts of the European nuclear medicine congress

    International Nuclear Information System (INIS)

    647 abstracts of oral and poster presentations show the results of applied science and research work in diagnostic and therapeutic nuclear medicine. Experiences with new diagnostic techniques, radiopharmaceuticals and instrumentation (e.g. radioimmunoscintigraphy, different dynamic organ function studies) in the fields of cardiology, endocrinology, gastroenterology, hematology, nephrology, oncology, and pediatrics are published as well as dosimetry problems. (TRV)

  12. Collaborative environment for nuclear medicine training

    Energy Technology Data Exchange (ETDEWEB)

    Brambilla, Claudia Regio; Dalpiaz, Gabriel Goulart; Giraffa, Lucia Maria, E-mail: claudinharb@gmail.co [Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS (Brazil); Silva, Ana Maria Marques da [Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS (Brazil). Dept. de Fisica; Silva Junior, Neivo da [Pontificia Universidade Catolica do Rio Grande do Sul (HSL-PUCRS), Porto Alegre, RS (Brazil). Hospital Sao Lucas; Ferreto, Tiago Coelho; Rose, Cesar Augusto Fonticielha de [Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS (Brazil). Inst. de Informatica; Silva, Vinicius Duval da [Pontificia Universidade Catolica do Rio Grande do Sul (FAMED/PUCRS), Porto Alegre, RS (Brazil). Escola de Medicina. Dept. de Patologia e Radiacoes

    2011-05-15

    Objective: To validate the proposal for development of a virtual collaborative environment for training of nuclear medicine personnel. Materials and Methods: Organizational assumptions, constraints and functionalities that should be offered to the professionals in this field were raised early in the development of the environment. The prototype was developed in the Moodle environment, including data storage and interaction functionalities. A pilot interaction study was developed with a sample of specialists in nuclear medicine. Users' opinions collected by means of semi-structured questionnaire were submitted to quantitative and content analysis. Results: The proposal of a collaborative environment was validated by a learning courses of nuclear medicine professionals and considered as an aid in the training in this field. Suggestions for improvements and new functionalities were made. There is a need to establish a program for education of moderators specifically for this environment, considering the different interaction characteristics as the online and conventional teaching methods are compared. Conclusion: The collaborative environment will allow the exchange of experiences and case discussions among professionals from institutions located in different regions all over the country, enhancing the collaboration among them. Thus, the environment can contribute in the early and continued education of nuclear medicine professionals. (author)

  13. Collaborative environment for nuclear medicine training

    International Nuclear Information System (INIS)

    Objective: To validate the proposal for development of a virtual collaborative environment for training of nuclear medicine personnel. Materials and Methods: Organizational assumptions, constraints and functionalities that should be offered to the professionals in this field were raised early in the development of the environment. The prototype was developed in the Moodle environment, including data storage and interaction functionalities. A pilot interaction study was developed with a sample of specialists in nuclear medicine. Users' opinions collected by means of semi-structured questionnaire were submitted to quantitative and content analysis. Results: The proposal of a collaborative environment was validated by a learning courses of nuclear medicine professionals and considered as an aid in the training in this field. Suggestions for improvements and new functionalities were made. There is a need to establish a program for education of moderators specifically for this environment, considering the different interaction characteristics as the online and conventional teaching methods are compared. Conclusion: The collaborative environment will allow the exchange of experiences and case discussions among professionals from institutions located in different regions all over the country, enhancing the collaboration among them. Thus, the environment can contribute in the early and continued education of nuclear medicine professionals. (author)

  14. Traumatic Brain Injury: Nuclear Medicine Neuroimaging

    NARCIS (Netherlands)

    Sánchez-Catasús, Carlos A; Vállez Garcia, David; Le Riverend Morales, Eloísa; Galvizu Sánchez, Reinaldo; Dierckx, Rudi; Dierckx, Rudi AJO; Otte, Andreas; de Vries, Erik FJ; van Waarde, Aren; Leenders, Klaus L

    2014-01-01

    This chapter provides an up-to-date review of nuclear medicine neuroimaging in traumatic brain injury (TBI). 18F-FDG PET will remain a valuable tool in researching complex mechanisms associated with early metabolic dysfunction in TBI. Although evidence-based imaging studies are needed, 18F-FDG PET i

  15. Nuclear medicine diagnostics of malignant tumors

    International Nuclear Information System (INIS)

    The monography deals with the localization diagnosis in nuclear medicine. After general remarks on technical and physical fundamentals and on methods and devices for scintigraphic localization of malignant tumors, specific scintiscanning of malignancies of thyroid, bones, liver, lungs, pancreas, adrenal glands, brain lymph nodes and eyes is discussed in detail. Numerous relevant references are added to each chapter

  16. Neuroimaging in nuclear medicine: drug addicted brain

    International Nuclear Information System (INIS)

    Addiction to illicit drugs in one of today's most important social issues. Most addictive drugs lead to irreversible parenchymal changes in the human brain. Neuroimaging data bring to light the pharmacodynamics and pharmacokinetics of the abused drugs, and demonstrate that addiction is a disease of the brain. Continuous researches better illustrate the neurochemical alterations in brain function, and attempt to discover the links to consequent behavioral changes. Newer hypotheses and theories follow the numerous results, and more rational methods of approaching therapy are being developed. Substance abuse is on the rise in Korea, and social interest in the matter as well. On the other hand, diagnosis and treatment of drug addiction is still very difficult, because how the abused substance acts in the brain, or how it leads to behavioral problems in not widely known. Therefore, understanding the mechanism of drug addiction can improve the process of diagnosing addict patients, planning therapy, and predicting the prognosis . Neuroimaging approaches by nuclear medicine methods are expected to objectively judge behavioral and neurochemical changes, and response to treatment. In addition, as genes associated with addictive behavior are discovered, functional nuclear medicine images will aid in the assessment of individuals. Reviewing published literature on neuroimaging regarding nuclear medicine is expected to be of assistance to the management of drug addict patients. What's more, means of applying nuclear medicine to the care of drug addict patients should be investigated further

  17. Neuroimaging in nuclear medicine: drug addicted brain

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yong-An; Kim, Dae-Jin [The Catholic University of Korea, Seoul (Korea, Republic of)

    2006-02-15

    Addiction to illicit drugs in one of today's most important social issues. Most addictive drugs lead to irreversible parenchymal changes in the human brain. Neuroimaging data bring to light the pharmacodynamics and pharmacokinetics of the abused drugs, and demonstrate that addiction is a disease of the brain. Continuous researches better illustrate the neurochemical alterations in brain function, and attempt to discover the links to consequent behavioral changes. Newer hypotheses and theories follow the numerous results, and more rational methods of approaching therapy are being developed. Substance abuse is on the rise in Korea, and social interest in the matter as well. On the other hand, diagnosis and treatment of drug addiction is still very difficult, because how the abused substance acts in the brain, or how it leads to behavioral problems in not widely known. Therefore, understanding the mechanism of drug addiction can improve the process of diagnosing addict patients, planning therapy, and predicting the prognosis . Neuroimaging approaches by nuclear medicine methods are expected to objectively judge behavioral and neurochemical changes, and response to treatment. In addition, as genes associated with addictive behavior are discovered, functional nuclear medicine images will aid in the assessment of individuals. Reviewing published literature on neuroimaging regarding nuclear medicine is expected to be of assistance to the management of drug addict patients. What's more, means of applying nuclear medicine to the care of drug addict patients should be investigated further.

  18. [Nuclear medicine for evaluation of liver functions].

    Science.gov (United States)

    Yamamoto, K

    1994-05-01

    The clinical usefulness of colloid liver scintigraphy to detect space occupying lesions in the liver has been reduced by X-ray CT and ultrasonography. However, scintigraphic examinations have potentials for characteristic diagnosis of liver tumors, such as 99mTc RBC SPECT for hepatic hemangioma, 99mTc PMT for positive imaging of hepatocellular carcinoma and its extrahepatic metastasis, and radioimmunoscintigraphy for metastatic tumors. Moreover, prediction of the prognosis and monitoring therapeutic effect to liver cancer can be made by the use of nuclear medicine techniques. Recently, 99mTc galactosyl serum albumin (GSA), a newly developed radiotracer to evaluate hepatocyte function, has become commercially available. Quantitative parameters of liver functions can be obtained by analysis of time-activity curve in blood and liver after 99mTc-GSA administration. In several cases, 99mTc-GSA study showed intrahepatic unevenness of function, which could not be depicted by other imaging examinations. Positron emission tomography (PET) with 18F-fluoro-2-deoxy glucose (FDG) is useful to detect malignant tumors in the liver. Since PET can provide absolutely quantitative data in better resolution, it is expected that regional true metabolic functions in the liver may be able to be quantitatively evaluated with PET in near future. PMID:8028225

  19. Nuclear medicine and imaging research (quantitative studies in radiopharmaceutical science). Progress report, January 1, 1984-December 31, 1984

    International Nuclear Information System (INIS)

    This report presents progress in the areas of cardiac nuclear medicine, other imaging studies, investigations with biomolecules, and assessment of risks associated with the clinical use of radiopharmaceuticals

  20. Quantitative Nuclear Medicine. Chapter 17

    International Nuclear Information System (INIS)

    Planar imaging is still used in clinical practice although tomographic imaging (single photon emission computed tomography (SPECT) and positron emission tomography (PET)) is becoming more established. In this chapter, quantitative methods for both imaging techniques are presented. Planar imaging is limited to single photon. For both SPECT and PET, the focus is on the quantitative methods that can be applied to reconstructed images

  1. Basic Physics for Nuclear Medicine. Chapter 1

    International Nuclear Information System (INIS)

    The technologies used in nuclear medicine for diagnostic imaging have evolved over the last century, starting with Röntgen’s discovery of X rays and Becquerel’s discovery of natural radioactivity. Each decade has brought innovation in the form of new equipment, techniques, radiopharmaceuticals, advances in radionuclide production and, ultimately, better patient care. All such technologies have been developed and can only be practised safely with a clear understanding of the behaviour and principles of radiation sources and radiation detection. These central concepts of basic radiation physics and nuclear physics are described in this chapter and should provide the requisite knowledge for a more in depth understanding of the modern nuclear medicine technology discussed in subsequent chapters

  2. The importance of HIFAR to nuclear medicine

    International Nuclear Information System (INIS)

    Since its official opening on 26 January 1960, the HIFAR research reactor operated by the Australian Nuclear Science and Technology Organisation (ANSTO) at Lucas Heights near Sydney has been used to support an expanding nuclear medicine market. HIFAR has characteristics which make it very suitable for this role and the effect has been to make ANSTO the dominant supplier of reactor-based radiopharmaceuticals in Australia and a significant exporter. While HIFAR has capacity to support limited increased production, its future requires government decisions. The author concluded that the absence of an operational research reactor in Australia and the lack of another local source of neutrons could directly affect the practice of nuclear medicine in the country and the level of presently increasing exports

  3. Quantitative Analysis in Nuclear Medicine Imaging

    CERN Document Server

    2006-01-01

    This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable increase in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of radionuclides for diagnosis and therapy has origins dating back almost to the discovery of natural radioactivity itself, radionuclide therapy and, in particular, targeted radionuclide therapy has only recently emerged as a promising approach for therapy of cancer and, to a lesser extent, other diseases. As effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. ...

  4. Fourth congress of the South African Society of Nuclear Medicine

    International Nuclear Information System (INIS)

    This seminar contains 68 papers. Sixty three papers were indexed. Five papers were considered out of scope for INIS. The implementation of nuclear medicine in the following fields were discussed: neurology, cardiology, monoclonal antibodies, endocrinology, nuclear medicine physics, and radiopharmacy

  5. Factor analysis of dynamic structures in nuclear medicine

    International Nuclear Information System (INIS)

    In the field of data processing in nuclear medicine, we applied the principal component analysis to the data acquired by the method of dynamic data acquisition. The radioisotope, taken in the body, shows inherent dynamic structures at the region of internal organ. We make some inherent patterns (Physiological Components) from T. A. C. (Time Activity Curve), and we represent dynamic structures of inherent patterns as functional image by the operation between inherent pattern and acquired data. This approach is called a Factor Analysis. In this paper, we introduce 1) The principle of factor analysis and its application to nuclear medicine, 2) the clinical application of factor analysis on SCINTIPAC-2400, and 3) the examinations and the comparison with other clinical application. (author)

  6. MEDICINAL VESICULATION THERAPY AND ITS CLINICAL APPLICATION

    Institute of Scientific and Technical Information of China (English)

    WANG Wei; LIU Haijing; SUN Zhanling

    2002-01-01

    In this paper, the authors introduce medicinal vesiculation therapy from its origin, points for attention in clinical application, and their individual experiences. In clinical application, the authors advocate: ① avoid using drugs that are over-irritating in the property, and strictly controlling the dose of drugs end the duration of application,②) in selection of drugs, some factors as patients' conditions, the season, the geographic location, etc. should be taken into account. In the present paper, 3 typical cases of bronchial asthma, tonsil swelling and facial paralysis treated with medicinal vesiculation therapy are introduced. Clinical practice demonsetrates that this therapy is economical,simple and convenient and fairly effective in treatment of some chronic diseases.

  7. Programmatic activities of IAEA in nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine is high-tech medicine. Nevertheless, it is essential for addressing important health problems of people living in developing countries also. Not only is it sometimes expensive to start with, it also involves a lot of technical know-how, requiring transfer of technology from developed to the developing countries. The rapid development of nuclear medicine, of sophisticated instrumentation and radiopharmaceuticals has resulted in an enormous increase in costs and in the need for maintaining quality. These constitute a challenge and a venture when promoting nuclear medicine globally and particularly in developing countries. No other international organization except IAEA has any specific mandate for application of nuclear energy in the area of human health. WHO has no specific programin nuclear medicine, hence the importance of IAEA's involvement. The IAEA has, ever since its inception, given high priority to enhancing the awareness and capabilities of developing member states to employ nuclear technology for health care and medical research. Much of the Agency promoted research in nuclear medicine is delivered through the so called co-ordinated research projects (CRPs). The CRPs are normally organised as multi-center, prospective studies so that large volume of scientific data could be generated in a short period of 18-24 months. The research is normally done within an operational frame work, established and co-ordinated by the IAEA. The reason for this is that the results can be compared despite site or country specific differences. The methods and materials used for such studies usually conform to a predetermined standard. The protocols for various investigations, criteria for patient selection, mode of arriving at a final diagnosis and analysis of data from these multi-center studies are normally agreed upon by the Chief Scientific Investigators from each participating institution and the IAEA prior to the start of the actual work programme. The

  8. Hospital Intranet and Extranet in nuclear medicine

    International Nuclear Information System (INIS)

    Since two years ago nuclear medicine service of Laennec Hospital has implemented transmission and distribution networks of scintigraphic images. A new stage was reached at present by developing an Intranet and Extranet system for nursing units and other services of nuclear medicine. The Intranet link to the services of Laennec Hospital and AP HP is based on a image server connected to the service gamma camera and, after a possible post-processing, the images are transmitted in PCX format by e-mail, attached to the medical record. For communication between nuclear medicine services, a heavier procedure making use of a program for image processing under inter-file standards has been implemented. To achieve the Extranet link with services and physicians of town, exterior to AP HP, a procedure was installed which allows reaching any nursing unit or town physicians having at their disposal e-mail on a secured network. This procedure will be generalized when the Health secured network, linking the medical bodies to Health insurance institutions, will be operational. The interactive tele-medicine will be achieved by means of a procedure based on Internet cooperative tools (wild cards, video- and vision-conferences) which will permits in all situations an interactive work on all the transmitted patient files

  9. History and Perspectives of Nuclear Medicine in Thailand

    OpenAIRE

    Sombut Boonyaprapa

    2014-01-01

    In 1955, the first nuclear medicine division was established in Thailand by Professor Romsai Suwannik in the Department of Radiology, Siriraj Hospil, Mahidol University in Bangkok. In 1959 four years later, the second nuclear medicine division was established in the Department of Radiology, Chulalongkorn Hospital in Bangkok. The third nuclear medicine division was started in Rajvithi Hospital in Bangkok in 1961. The fourth nuclear medicine division was installed in Chiang Mai University which...

  10. Checklists for quality assurance and audit in nuclear medicine

    International Nuclear Information System (INIS)

    A series of checklists are given which aim to provide some guidance to staff in determining whether their working procedures in nuclear medicine are likely to produce a good service and avoid mistakes. The checklists relate to the special equipment used in nuclear medicine departments, radiopharmaceuticals, nuclear medicine staff, services to medical and other hospital staff and finally the service to patients. The checklists are relevant to an average nuclear medicine department performing less than 2000 imaging studies per year. (U.K.)

  11. Performance of dose calibrators used for nuclear medicine services

    International Nuclear Information System (INIS)

    This work show the results of the quality control tests from two different dose calibrators of a Nuclear Medicine Clinic in Sao Paulo. One of them has an ionization chamber (well type) and the other, Geiger-Mueller detectors (well configuration). As reference sources, Cobalt-57, Barium-133 and Caesium-137 were utilized. Also, an unsealed Technetium-99m source was used in some tests. Finally, the performance of both instruments was compared. (author)

  12. Nuclear Medicine: Use of Thallium 201 in Tumor Evaluation

    OpenAIRE

    Waxman, Alan D.

    1992-01-01

    The Council on Scientific Affairs of the California Medical Association presents the following inventory of items of progress in nuclear medicine. Each item, in the judgment of a panel of knowledgeable physicians, has recently become reasonably firmly established, both as to scientific fact and important clinical significance. The items are presented in simple epitome, and an authoritative reference, both to the item itself and to the subject as a whole, is generally given for those who may b...

  13. Proceedings of the Korean Society Nuclear Medicine Autumn Meeting 2002

    International Nuclear Information System (INIS)

    This proceedings contains articles of 2002 autumn meeting of the Korean Society Nuclear Medicine. It was held on November 15-16, 2002 in Seoul, Korea. This proceedings is comprised of 5 sessions. The subject titles of session are as follows: Cancer, Physics of nuclear medicine, Neurology, Radiopharmacy and biology, General nuclear medicine. (Yi, J. H.)

  14. Converting energy to medical progress [nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-04-01

    For over 50 years the Office of Biological and Environmental Research (BER) of the United States Department of Energy (DOE) has been investing to advance environmental and biomedical knowledge connected to energy. The BER Medical Sciences program fosters research to develop beneficial applications of nuclear technologies for medical diagnosis and treatment of many diseases. Today, nuclear medicine helps millions of patients annually in the United States. Nearly every nuclear medicine scan or test used today was made possible by past BER-funded research on radiotracers, radiation detection devices, gamma cameras, PET and SPECT scanners, and computer science. The heart of biological research within BER has always been the pursuit of improved human health. The nuclear medicine of tomorrow will depend greatly on today's BER-supported research, particularly in the discovery of radiopharmaceuticals that seek specific molecular and genetic targets, the design of advanced scanners needed to create meaningful images with these future radiotracers, and the promise of new radiopharmaceutical treatments for cancers and genetic diseases.

  15. Nuclear medicine: a public health issue

    International Nuclear Information System (INIS)

    Nuclear medicine offers a broad range of services for numerous diseases. By introducing radioactive molecules in the body, nuclear medicine can perform powerful and targeted acts from diagnostic to treatment. In western countries, one out of 2 people will benefit from it during his life, but the producers of radioactive nuclides are not very numerous. In France 80% of the scans are performed with Technetium-99m (99mTc) that is obtained from Molybdenum 99 (99Mo) produced in nuclear reactors. A shortage of 99mTc is expected during next years since the Osiris reactor is planned to be decommissioned at the end of 2015 and other reactors will be stopped for maintenance operations. The different techniques used in nuclear medicine brings contamination risks for both patients and medical staff. These risks are mitigated through an optimization of the dose delivered to the patient, the staff is monitored with the wearing of a dosimeter and is committed to regular medical tests and the handling of radioactive materials is made behind adequate biological shields. Radiation protection in the medical sector is submitted to time-consuming procedures that might be made more flexible and the knowledge of how other countries deal concretely with radiation protection would be beneficial. (A.C.)

  16. Converting energy to medical progress [nuclear medicine

    International Nuclear Information System (INIS)

    For over 50 years the Office of Biological and Environmental Research (BER) of the United States Department of Energy (DOE) has been investing to advance environmental and biomedical knowledge connected to energy. The BER Medical Sciences program fosters research to develop beneficial applications of nuclear technologies for medical diagnosis and treatment of many diseases. Today, nuclear medicine helps millions of patients annually in the United States. Nearly every nuclear medicine scan or test used today was made possible by past BER-funded research on radiotracers, radiation detection devices, gamma cameras, PET and SPECT scanners, and computer science. The heart of biological research within BER has always been the pursuit of improved human health. The nuclear medicine of tomorrow will depend greatly on today's BER-supported research, particularly in the discovery of radiopharmaceuticals that seek specific molecular and genetic targets, the design of advanced scanners needed to create meaningful images with these future radiotracers, and the promise of new radiopharmaceutical treatments for cancers and genetic diseases

  17. Converting Energy to Medical Progress [Nuclear Medicine

    Science.gov (United States)

    2001-04-01

    For over 50 years the Office of Biological and Environmental Research (BER) of the United States Department of Energy (DOE) has been investing to advance environmental and biomedical knowledge connected to energy. The BER Medical Sciences program fosters research to develop beneficial applications of nuclear technologies for medical diagnosis and treatment of many diseases. Today, nuclear medicine helps millions of patients annually in the United States. Nearly every nuclear medicine scan or test used today was made possible by past BER-funded research on radiotracers, radiation detection devices, gamma cameras, PET and SPECT scanners, and computer science. The heart of biological research within BER has always been the pursuit of improved human health. The nuclear medicine of tomorrow will depend greatly on today's BER-supported research, particularly in the discovery of radiopharmaceuticals that seek specific molecular and genetic targets, the design of advanced scanners needed to create meaningful images with these future radiotracers, and the promise of new radiopharmaceutical treatments for cancers and genetic diseases.

  18. Assessment of OEP health's risk in nuclear medicine

    Science.gov (United States)

    Santacruz-Gomez, K.; Manzano, C.; Melendrez, R.; Castaneda, B.; Barboza-Flores, M.; Pedroza-Montero, M.

    2012-10-01

    The use of ionizing radiation has been increased in recent years within medical applications. Nuclear Medicine Department offers both treatment and diagnosis of diseases using radioisotopes to controlled doses. Despite the great benefits to the patient, there is an inherent risk to workers which remains in contact with radiation sources for long periods. These personnel must be monitored to avoid deterministic effects. In this work, we retrospectively evaluated occupationally exposed personnel (OEP) to ionizing radiation in nuclear medicine during the last five years. We assessed both area and personal dosimetry of this department in a known Clinic in Sonora. Our results show an annual equivalent dose average of 4.49 ± 0.70 mSv in OEP without showing alarming changes in clinical parameters analyzed. These results allow us to conclude that health of OEP in nuclear medicine of this clinic has not been at risk during the evaluated period. However, we may suggest the use of individual profiles based on specific radiosensitivity markers.

  19. [Challenges for pathologists in clinical laboratory medicine].

    Science.gov (United States)

    Tezuka, F

    2001-06-01

    The number of pathologists in hospitals has been increasing and they are responsible for both surgical pathology and clinical laboratory medicine. In the future they will also play important roles in the modernized reform of the central laboratory as it establishes its own importance in improving the quality and safety of medical activities. As a pathologist, the author reports on challenges faced since assuming the present directorship of the department of laboratory medicine in 1995 including (a) establishing a decision-making system in collaboration with technologists, (b) improving expertise in the department through joining a variety of seminars, conferences and research activities, (c) publishing an annual department report, and (d) introducing both internal and external quality assessment. In the future, for young pathologists training in both pathology and laboratory medicine will be essential. PMID:11452548

  20. Radionuclides for nuclear medicine: a nuclear physicists' view

    DEFF Research Database (Denmark)

    Cantone, M.; Haddad, F.; Harissopoulos, S.; Jensen, Mikael; Jokinen, A.; Köster, U.; Lebeda, O.; Ponsard, B.; Ratzinger, U.; Stora, T.; Tarkanyi, F.; Van Duppen, P.

    NuPECC (the Nuclear Physics European Collaboration Committee, an expert committee of the European Science Foundation) has the mission to strengthen European Collaboration in nuclear science through the promotion of nuclear physics and its trans-disciplinary use and application. NuPECC is currently...... working on a report on “Nuclear Physics for Medicine” and has set up a working group to review the present status and prospects of radionuclides for nuclear medicine. An interim report will be presented to seek comments and constructive input from EANM members. In particular it is investigated how nuclear...... physics Methods and nuclear physics facilities are supporting the development and supply of medical radionuclides and how this support could be further strengthened in future. Aspects that will be addressed: •In recent years, the reactor-based supply chain of 99Mo/99mTc generators was repeatedly...

  1. Radionuclides for nuclear medicine: a nuclear physicists' view

    DEFF Research Database (Denmark)

    Cantone, M.; Haddad, F.; Harissopoulos, S.;

    2013-01-01

    NuPECC (the Nuclear Physics European Collaboration Committee, an expert committee of the European Science Foundation) has the mission to strengthen European Collaboration in nuclear science through the promotion of nuclear physics and its trans-disciplinary use and application. NuPECC is currently...... working on a report on “Nuclear Physics for Medicine” and has set up a working group to review the present status and prospects of radionuclides for nuclear medicine. An interim report will be presented to seek comments and constructive input from EANM members. In particular it is investigated how nuclear...... physics Methods and nuclear physics facilities are supporting the development and supply of medical radionuclides and how this support could be further strengthened in future. Aspects that will be addressed: •In recent years, the reactor-based supply chain of 99Mo/99mTc generators was repeatedly...

  2. Nuclear Medicine Physics: A Handbook for Teachers and Students. Endorsed by: American Association of Physicists in Medicine (AAPM), Asia–Oceania Federation of Organizations for Medical Physics (AFOMP), Australasian College of Physical Scientists and Engineers in Medicine (ACPSEM), European Federation of Organisations for Medical Physics (EFOMP), Federation of African Medical Physics Organisations (FAMPO), World Federation of Nuclear Medicine and Biology (WFNMB)

    International Nuclear Information System (INIS)

    This publication provides the basis for the education of medical physicists initiating their university studies in the field of nuclear medicine. The handbook includes 20 chapters and covers topics relevant to nuclear medicine physics, including basic physics for nuclear medicine, radionuclide production, imaging and non-imaging detectors, quantitative nuclear medicine, internal dosimetry in clinical practice and radionuclide therapy. It provides, in the form of a syllabus, a comprehensive overview of the basic medical physics knowledge required for the practice of medical physics in modern nuclear medicine

  3. Genomics and proteomics in nuclear medicine

    International Nuclear Information System (INIS)

    The results obtained from basic science deliver more information about many new molecular structures, which may serve as potential new diagnostic or even therapeutic targets. The selection and evaluation of these targets needs information concerning physiology, biochemistry and pharmacology. These data can be obtained at least in part by nuclear medicine technology. Nuclear medicine procedures can be applied for the assessment of the function and regulation of genes. This can be achieved by use of radiolabeled antisense molecules or reporter gene technology. New therapeutic approaches necessitate biodistribution studies at preclinical stages and methods delivering data about their effectiveness. Finally, procedures from biotechnology such as phagen display may be used for the development of new biomolecules for the isotope-based diagnostics and treatment. (orig.)

  4. Directory of computer users in nuclear medicine

    International Nuclear Information System (INIS)

    The Directory of Computer Users in Nuclear Medicine consists primarily of detailed descriptions and indexes to these descriptions. A typical Installation Description contains the name, address, type, and size of the institution and the names of persons within the institution who can be contacted for further information. If the department has access to a central computer facility for data analysis or timesharing, the type of equipment available and the method of access to that central computer is included. The dedicated data processing equipment used by the department in its nuclear medicine studies is described, including the peripherals, languages used, modes of data collection, and other pertinent information. Following the hardware descriptions are listed the types of studies for which the data processing equipment is used, including the language(s) used, the method of output, and an estimate of the frequency of the particular study. An Installation Index and an Organ Studies Index are also included

  5. Formulary: Pharmacologic interventions in nuclear medicine

    International Nuclear Information System (INIS)

    The purpose of this formulary is to provide the practitioner with a readily available reference addressed specifically at the pharmacology (i.e., chemistry, mechanism(s) of action, cautions, dosage, and available preparation(s)) of interventional drugs commonly used in nuclear medicine practice. Although the majority of these agents are intended for alternate therapeutic indications, the formulary is directed at and limited to information pertinent to their interventional use. In this regard, the majority of the presented material has been extrapolated from standard drug formularies or product inserts. Specific material related to published interventional nuclear medicine studies is referenced in the bibliography and/or can be found in the associated chapters of this book. The reader is advised to note not only the information related to the interventional drug, but also the statements regarding appropriate treatment or avoidance of associated side effects. To facilitate utilization, the interventional drugs are listed in alphabetical order, rather than by therapeutic class

  6. Directory of computer users in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Erickson, J.J.; Gurney, J.; McClain, W.J. (eds.)

    1979-09-01

    The Directory of Computer Users in Nuclear Medicine consists primarily of detailed descriptions and indexes to these descriptions. A typical Installation Description contains the name, address, type, and size of the institution and the names of persons within the institution who can be contacted for further information. If the department has access to a central computer facility for data analysis or timesharing, the type of equipment available and the method of access to that central computer is included. The dedicated data processing equipment used by the department in its nuclear medicine studies is described, including the peripherals, languages used, modes of data collection, and other pertinent information. Following the hardware descriptions are listed the types of studies for which the data processing equipment is used, including the language(s) used, the method of output, and an estimate of the frequency of the particular study. An Installation Index and an Organ Studies Index are also included. (PCS)

  7. Instrumentation and organisation in cardiovascular nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear techniques, although generally accepted in medicine, require efficient instrumentation and close cooperation between the expert in nuclear medicine and the cardiologist. The methods most frequently applied are 201Tl scintiscanning, radionuclide angiocardiography and radionuclide ventriculography. Combined application of the latter two is particularly efficient. Tl scintiscanning is most frequently applied to determine myocardial vitality, the first-pass technique is used for morphological and the steady-state technique for functional examinations. Functional examinations of the coronary arteries are carried out directly by myocardial scintiscanning while radionuclide ventriculography yields information on the heamodynamic effect of stenosis of the coronary arteries via measurement of the ventricular function. In consequence, there is a wide range of indications in which myocardial scintiscanning and radionuclide ventriculography are equally applicable; myocardial scintiscanning has the advantage of simplicity while radionuclide ventriculography yields important supplementary information on the ventricular function. (orig.)

  8. Nuclear medicine therapy of neuroblastoma

    Energy Technology Data Exchange (ETDEWEB)

    Hoefnagel, C.A. [Amsterdam The Netherlands Cancer Institute, Amsterdam (Netherlands). Dept. of Nuclear Medicine

    1999-12-01

    Specific targeting of radionuclides to neuroblastoma, a neural crest tumor occurring predominantly in young children and associated with a relatively poor prognosis, may be achieved via the metabolic route (Mibg), receptor binding (peptides) or immunological approach (antibodies). The clinical role of {sup 1}31{sup I}-Mibg therapy and radioimmunotherapy in neuroblastoma is discussed. In recurrent or progressive metastatic disease after conventional treatment modalities have failed, {sup 1}31{sup I}-Mibg therapy, with an overall objective response rate of 35%, is probably the best palliative treatment, as the invasiveness and toxicity of this therapy compare favourably with that of chemotherapy, immunotherapy and external beam radiotherapy. In patients presenting with inoperable stage III and IV neuroblastoma, {sup 1}31{sup I}-Mibg therapy at diagnosis is at least as effective as combination chemotherapy but is associated with much less toxicity. In patients with recurrent disease {sup 1}31{sup I}-Mibg therapy in combination with hyperbaric oxygen therapy proved feasible and encouraging effects on survival have ben observed. Attempts to intensify the treatment in relapsed patients by combination of {sup 1}31{sup I}-Mibg therapy with high dose chemotherapy and/or total body irradiation have met with considerable toxicity. Developments in Mibg therapy aiming at improving the therapeutic index are mentioned. Early results of radioimmunotherapy using {sup 1}31{sup I}-UJ13A or {sup 1}31{sup I}-3F8 monoclonal antibodies have shown moderate objective response and considerable side effects in patients with stage IV neuroblastoma, who had relapsed or failed conventional therapy. New developments in radioimmunotherapy of neuroblastoma include the use of chimeric antibodies, the enhancement of tumor uptake by modulation of antigen expression or by increasing the tumor perfusion/vascularity/permeability, the use of other labels and multistep targeting techniques, e.g. using

  9. Medical isotopes and emerging nuclear medicine technologies

    International Nuclear Information System (INIS)

    This presentation discusses medical isotopes and the emerging nuclear medicine technologies as well as the impact of Chalk River reactor shutdown on patient management and diseases. It outlines the chain of supply of isotopes across the globe and isotope shortage impact. It recommends the following mitigating strategies: modifications of scanning techniques, adjustment of patient scheduling, optimization of Tc-99m generator use, patient prioritization, alternate procedures and PET scanning.

  10. Nuclear Medicine Imaging in the Pediatric Patient

    OpenAIRE

    Loveless, Vivian

    2006-01-01

    Pediatric nuclear medicine provides a wealth of information on a variety of disease states; however, precautions on dosing have to be taken into consideration. Also, expertise in conducting procedures and interpreting the results in pediatric patients is necessary. Emphasis is placed on diagnostic studies involving the central nervous system, musculoskeletal system, genitourinary system, gastrointestinal system, endocrine system, pulmonary system, and cardiovascular system along with a brief ...

  11. Nuclear medicine imaging of diabetic foot infection

    International Nuclear Information System (INIS)

    Full text: Osteomyelitis of the foot is the most frequent complication in diabetic patients. Nuclear medicine plays an important role in diagnosis and for therapy follow-up, using different tracers. We reviewed 57 papers on diabetic foot imaging (published from 1982 to 2004, 50 original papers and 7 reviews), for a total of 2889 lesions. Data analysis has been carried out to establish which imaging technique could be used as a 'gold standard' for diagnosis of infection and to evaluate the extent of disease and to monitor the efficacy of therapy. Data analysis revealed that three-phase bone-scan is sensitive but not specific whereas specificity and diagnostic accuracy of 99mTc-WBC scintigraphy is higher than 111In- WBC scintigraphy. In the forefoot leukocyte scintigraphy may be useful for diagnosis of osteomyelitis and for monitoring the response to medical treatment. In the mid/hind foot the leukocytes uptake is not related only to the presence of infected region, but it is attributed to inflammation, fractures and reparative processes. Other radiopharmaceuticals such as 99mTc/111In-HIG, radiolabelled antibody and their fragments, showed high sensibility, but lower specificity than WBC (96.8/66.5, 95.8/70.2, 91.3/62 vs 85.8/84.5). Conclusion: It emerged that in the forefoot when clinical suspicious of osteomyelitis is low and medical treatment is contemplated, three-phase bon scan is the procedure of choice. A positive test is not diagnostic for osteomyelitis, and radiolabelled WBC scintigraphy is necessary. In the mid/hind foot, diagnosis of neuropathic joint with infection is problematic. Radiolabelled WBC imaging is probably the most accurate test for determining the presence of infection. Although a negative study strongly indicate the absence of osteomyelitis, it is important to note that a positive result requires a complementary study with marrow agent. (author)

  12. Nuclear medicine solutions in winter sports problems

    International Nuclear Information System (INIS)

    Full text: The diagnostic workup of acute Winter Sports injuries is done by Conventional X Ray, CT and MRI. Chronic injuries as stress reactions are best investigated by Nuclear Medicine procedures: Snow Boarding: In Snow-Boarding chronic injuries are mostly seen as local increased uptake laterally in the lower third of the Fibula of the front leg together with Tibial increase medially in the other leg. Skiing: Chronic Skiing injuries are less asymmetrical and mostly seen on the apex of the patella. Chronic Feet Problems: A different chronic problem is the reduced blood perfusion in the feet if hard, tightened boots are used for longer time by professional ski instructors and racers. Flow difference between the foot in the boot and the other without boot are dramatic as measured by Nuclear Medicine Procedures and MRI. Pulmonary Embolism: Acute pulmonary embolism caused by thrombi originating at the site of constant pressure on the back rim of ski boots is not uncommon in older skiers (seek and you will find), but never seen in the younger group of Snow-Boarders. Copyright (2002) The Australian and New Zealand Society of Nuclear Medicine Inc

  13. Hand exposure in nuclear medicine workers

    International Nuclear Information System (INIS)

    As a result of the gamma radiation emitted by radioactive elements (e.g. 99mTc and 131I) used in nuclear medicine laboratories for diagnostic and therapeutic purposes, nuclear medicine workers are exposed to whole-body doses. These doses are usually measured by using individual film dosemeters. Lead or lead glass shields used during the handling of radioisotope minimise the whole-body dose received. Nevertheless, part of the job has to be performed manually, hence the hands are more exposed to radiation. This paper presents the results of measuring the equivalent dose to the hands of workers employed in five selected nuclear medicine laboratories where technetium and iodine radioisotopes are in common use. Sixty workers, including physicians, nurses, radiopharmacists and technicians, were included in the study. Doses were measured at 1 month intervals. The study indicated that, in some instances, the danger of radiation dose to the hand may be significant. Monthly doses exceed 50 mSv, which may suggest that an annual dose may be higher than 500 mSv. (author)

  14. Impact of Obesity on Nuclear Medicine

    International Nuclear Information System (INIS)

    Obesity with its alarming increase in number among adults and children represents a significant health problem with serious medical, social, psychological and economical reverberations. The burden that is put upon the medical care system due to this problem has a significant effect on the medical services provided including radiological imaging. The effect of obesity on nuclear medicine services includes many aspects starting with problems with patient preparation prior to imaging, while radiotracer administration and during patient imaging. In addition, altered imaging techniques, including timing, imaging duration, and protocol alteration. Furthermore, obtaining suboptimal images brought by artifacts due to soft tissue attenuation and incomplete whole body coverage during image acquisition and performing sub optimal quantification, especially in positron emission tomography. Finally, dealing with mechanical problems such as weight limits of the imaging table and bore size in PET or SPECT/CT. These issues are discussed in this review clarifying the impact of this epidemic health problem on the nuclear medicine services and possible solutions to overcome the difficulties encountered in the nuclear medicine department. (author)

  15. Nuclear oncology, a fast growing field of nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Olivier, Pierre E-mail: p.olivier@chu-nancy.fr

    2004-07-11

    Nuclear Medicine in oncology has been for a long time synonymous with bone scintigraphy, the first ever whole body imaging modality, and with treatment of thyroid cancer with iodine-131. More recently, somatostatin receptor scintigraphy (SRS) using peptides such as {sup 111}In-labelled octreotide became a reference imaging method in the detection and staging of neuroendocrine tumors while {sup 131}I- and {sup 123}I-MIBG remain the tracers of reference for pheochromocytomas and neuroblastomas. Lymphoscintigraphic imaging based on peritumoral injection of {sup 99m}Tc-labelled colloids supports, in combination with per operative detection, the procedure of sentinel node identification in breast cancers and melanomas. Positron Emission Tomography (PET) is currently experiencing a considerable growth in oncology based on the use of {sup 18}F-FDG (fluorodeoxyglucose), a very sensitive, although non-specific, tumor tracer. Development of instrumentation is crucial in this expansion of PET imaging with new crystals being more sensitive and hybrid imagers that permit to reduce the acquisition time and offer fused PET-CT images. Current developments in therapy can be classified into three categories. Radioimmunotherapy (RIT) based on monoclonal antibodies (or fragments) labelled with beta-emitters. This technique has recently made its entrance in clinical practice with a {sup 90}Y-labelled anti-CD20 antibody ({sup 90}Y-ibritumomab tiuxetan (Zevalin{sup [reg]})) approved in US for the treatment of some subtypes of non-Hodgkin's lymphoma. Radionuclide-bone pain palliation has experienced developments with {sup 153}Sm-EDTMP, 186Re-HEDP or {sup 89}Sr, efficient in patients with widespread disease. Last, the same peptides, as those used in SRS, are being developed for therapy, labelled with {sup 90}Y, {sup 111}In or {sup 177}Lu in patients who failed to respond to other treatments. Overall, nuclear oncology is currently a fast growing field thanks to the combined

  16. Proceedings of 2nd Korea-China Congress of Nuclear Medicine and the Korean Society Nuclear Medicine Spring Meeting 2000

    International Nuclear Information System (INIS)

    This proceedings contains articles of 2nd Korea-China Congress of Nuclear Medicine and 2000 spring meeting of the Korean Society Nuclear Medicine. It was held on May 17-19, 2000 in Seoul, Korean. This proceedings is comprised of 6 sessions. The subject titles of session are as follows: general nuclear medicine, neurology, oncology, radiopharmacy and biology, nuclear cardiology, nuclear cardiology: physics and instrumentation and so on. (Yi, J. H.)

  17. Radiopharmaceuticals in Nuclear Medicine: Evolution and Role in Dentistry

    OpenAIRE

    Vani, Chappidi; Nagalaxmi, V.; Singh, Anshul; Zardi, Faisal Taiyebali; Lalitha, CH

    2013-01-01

    NUCLEAR MEDICINE is the branch of medicine and medical imaging that uses radiation emitted by a radio-pharmaceutical to provide information about both the structure and function of organ systems within the body thereby aiding in the diagnosis and treatment of a disease. This unparalleled branch of radiology concerns with the diagnostic and therapeutic use of radionuclides. The most striking feature that distinguishes Nuclear Medicine from other Imaging Modalities is that Nuclear Medicine aids...

  18. Basic science of nuclear medicine the bare bone essentials

    CERN Document Server

    Lee, Kai H

    2015-01-01

    Through concise, straightforward explanations and supporting graphics that bring abstract concepts to life, the new Basic Science of Nuclear Medicine—the Bare Bone Essentials is an ideal tool for nuclear medicine technologist students and nuclear cardiology fellows looking for an introduction to the fundamentals of the physics and technologies of modern day nuclear medicine.

  19. Handbook of nuclear medicine practice in developing countries

    International Nuclear Information System (INIS)

    This ''Handbook of Nuclear Medicine Practices in the Developing Countries'' is meant primarily for those, who intend to install and practice nuclear medicine in a developing country. By and large, the conventional Textbooks of nuclear medicine do note cater to the special problems and needs of these countries. The Handbook is not trying to replace these textbooks, but supplement them with special information and guidance, necessary for making nuclear medicine cost-effective and useful in a hospital of a developing country. It is written mostly by those, who have made success in their careers in nuclear medicine, in one of these countries. One way to describe this Handbook will be that it represents the ways, in which, nuclear medicine is practised in the developing countries, described by those, who have a long and authentic experience of practising nuclear medicine in a developing country

  20. The Current Status and Future Perspectives of Nuclear Medicine in Korea

    OpenAIRE

    Lee, Myung Chul; Oh, So Won; Chung, June-Key; Lee, Dong Soo

    2010-01-01

    Since the introduction of nuclear medicine in 1959, Korea accomplished a brilliant development in terms of both clinical practice and research activities, which was mainly due to the dedication of nuclear medicine specialists, consisting of physicians, technicians, and scientists, and strong support from the Korean Government. Now, Korea has 150 medical institutes, performing approximately 561,000 nuclear imaging procedures and 11.6 million in vitro studies in 2008, and ranked fourth in the n...

  1. Regional approach to training nuclear medicine technologists: the Rochester experience

    International Nuclear Information System (INIS)

    A university-based baccalaureate nuclear medicine program with a consortium of 11 hospital clinical training sites has been developed in Western New York State to meet the manpower needs in the region. A multifaceted clinical rotation schedule was designed into the program in order to provide students with the broadest possible learning experiences in a variety of hospital and training environments. The success of this educational consortium has depended heavily upon the open channels of communication established among the program's many constituents. The regional demand for technologists is being met as 64% of the graduates take their first job in New York State

  2. Radionuclide calibrator comparisons and quality improvement in nuclear medicine.

    Science.gov (United States)

    Oropesa, P; Woods, M J; Olsovcová, V; dos Santos, J A

    2008-03-01

    The traceability of activity measurements performed during the development phase of the radiopharmaceutical and in its clinical application is essential for establishing the comparability of clinical results reported in the nuclear medicine field. This paper presents and discusses the evaluation over time of the quality of activity measurement results obtained in Cuban nuclear medicine, on the basis of statistical samples taken during the radionuclide calibrator comparison program. An attempt is also made to evaluate the role played by such comparisons in quality measurement improvement in nuclear medicine, on the basis of results obtained in a number of countries and published by several authors over a period of time. Specifically, improvements of the measurement performance over time assessed by such exercises were found dissimilar in magnitudes for different countries. Two phases could be distinguished in the improvement process over time. Firstly, a fast improvement can be obtained resulting from the improvement in measurement accuracy of devices. After that, the achievement of new and sustained improvements goes slowly and requires an application of quality assurance programs where the qualification upgrading of personnel become an essential point. PMID:17855099

  3. Place of the nuclear medicine in the clinical development of the gene therapy; Place de la medecine nucleaire dans le developpement clinique de la therapie genique

    Energy Technology Data Exchange (ETDEWEB)

    Crochet, T. [Montpellier-1 Univ., 34 (France); Vis, J. de [Centre Hospitalier Universitaire, Hopital Saint Eloi, Institut de Recherche en Biotherapie, 34 - Montpellier (France); Vincent, D. [Centre Hospitalier Universitaire de Nimes, Service de Medecine Interne, Hopital Caremeau, 30 - Nimes (France); Zanca, M. [Centre Hospitalier Universitaire, Hopital Guy de Chauliac, Service de Medecine Nucleaire, 34 - Montpellier (France)

    2006-10-15

    Although gene therapy has been proposed first for genetic diseases, its concept has been extended to many acquired diseases, owing to a better understanding of pathology at a molecular level. Overall, very few trials have shown to be efficient, and safety concerns have emerged, as a result of several patients deaths. There is a need for new techniques able to improve both the knowledge of the therapeutic gene fate once administered and the early detection of events likely to lead to serious adverse events. In vivo imaging of a reporter gene associated with the therapeutic one is certainly the most promising technique for these goals. Among available imaging modalities, nuclear imaging is the most likely to be applied to patients. This review begins with a summary of current knowledge about the steps that a therapeutic gene has to cross from vector delivery to appropriate expression in target cells. We show how gene imaging could allow to investigate many pitfalls of trials by providing a better understanding of these steps in patients. The reporter genes available for nuclear imaging are presented in the second section, through animal studies. Then, relevant examples of clinical trials are presented. These include cancer (suicide gene therapy and adoptive immunotherapy), ischemic heart diseases and cystic fibrosis. The results are commented with emphasis on the role of nuclear imaging to address the questions raised by these studies, and imaging studies carried out on animals or patients for the corresponding diseases or organs are presented. The results obtained in animal studies warrant the introduction of gene imaging in clinical trials. (authors)

  4. The integral formation of the university technologists in nuclear medicine

    International Nuclear Information System (INIS)

    Full text: Nuclear medicine has contributed to notable benefits to the human health from the very beginning. The Radioisotopes techniques, as well as the ionizing radiation used, have evolved providing functional and anatomical information of the patient, through non-invasive methods. With reference to Radiological Protection, the justification of each one of these practices and its perfect execution is intimately related to the benefit provided to the patients. The National Atomic Energy Commission apart from favouring the scientific and technological development, considers indispensable to work thoroughly on the professional training of the prospective technologists. Our over twenty-year experience in organizing and delivering courses of Technologists in Nuclear Medicine, although based on a much simpler program, have allowed the Institute of Nuclear Studies of the Ezeiza Atomic Center to acquire the capacity of developing a program to train highly qualified Technologists in that field. This project represents a step forward of great importance to the graduates qualification, since they will have the endorsement of CNEA and of the Faculty of Medicine of the Maimonides University. These are the three outstanding characteristics agreed on: 1.- General Education, carried out by subjects closely related to the optimisation of the relation Technologist - Patient - Environment and represented by: Radiological Protection and Hospital Security, Psychology, Ethics and Professional Medical Ethics, Nursing, English, Hygiene and Hospital Security and Management of the Quality in Services of Health. 2.- Diagnostic Procedures: planned according to organs, apparatuses or systems which are horizontally crossed by the anatomy, physiology and physiopathology Preparation of the patient, indications, main counter indications, radiopharmaceuticals, mechanisms of incorporation, pathologies, clinical protocols, instrumentation, post radiopharmaceuticals administration imaging

  5. SU-E-I-65: The Joint Commission's Requirements for Annual Diagnostic Physics Testing of Nuclear Medicine Equipment, and a Clinically Relevant Methodology for Testing Low-Contrast Resolution

    Energy Technology Data Exchange (ETDEWEB)

    West, W. Geoffrey; Gray, David Clinton [West Physics Consulting, Atlanta, GA (United States)

    2014-06-01

    Purpose: To introduce the Joint Commission's requirements for annual diagnostic physics testing of all nuclear medicine equipment, effective 7/1/2014, and to highlight an acceptable methodology for testing lowcontrast resolution of the nuclear medicine imaging system. Methods: The Joint Commission's required diagnostic physics evaluations are to be conducted for all of the image types produced clinically by each scanner. Other accrediting bodies, such as the ACR and the IAC, have similar imaging metrics, but do not emphasize testing low-contrast resolution as it relates clinically. The proposed method for testing low contrast resolution introduces quantitative metrics that are clinically relevant. The acquisition protocol and calculation of contrast levels will utilize a modified version of the protocol defined in AAPM Report #52. Results: Using the Rose criterion for lesion detection with a SNRpixel = 4.335 and a CNRlesion = 4, the minimum contrast levels for 25.4 mm and 31.8 mm cold spheres were calculated to be 0.317 and 0.283, respectively. These contrast levels are the minimum threshold that must be attained to guard against false positive lesion detection. Conclusion: Low contrast resolution, or detectability, can be properly tested in a manner that is clinically relevant by measuring the contrast level of cold spheres within a Jaszczak phantom using pixel values within ROI's placed in the background and cold sphere regions. The measured contrast levels are then compared to a minimum threshold calculated using the Rose criterion and a CNRlesion = 4. The measured contrast levels must either meet or exceed this minimum threshold to prove acceptable lesion detectability. This research and development activity was performed by the authors while employed at West Physics Consulting, LLC. It is presented with the consent of West Physics, which has authorized the dissemination of the information and/or techniques described in the work.

  6. SU-E-I-65: The Joint Commission's Requirements for Annual Diagnostic Physics Testing of Nuclear Medicine Equipment, and a Clinically Relevant Methodology for Testing Low-Contrast Resolution

    International Nuclear Information System (INIS)

    Purpose: To introduce the Joint Commission's requirements for annual diagnostic physics testing of all nuclear medicine equipment, effective 7/1/2014, and to highlight an acceptable methodology for testing lowcontrast resolution of the nuclear medicine imaging system. Methods: The Joint Commission's required diagnostic physics evaluations are to be conducted for all of the image types produced clinically by each scanner. Other accrediting bodies, such as the ACR and the IAC, have similar imaging metrics, but do not emphasize testing low-contrast resolution as it relates clinically. The proposed method for testing low contrast resolution introduces quantitative metrics that are clinically relevant. The acquisition protocol and calculation of contrast levels will utilize a modified version of the protocol defined in AAPM Report #52. Results: Using the Rose criterion for lesion detection with a SNRpixel = 4.335 and a CNRlesion = 4, the minimum contrast levels for 25.4 mm and 31.8 mm cold spheres were calculated to be 0.317 and 0.283, respectively. These contrast levels are the minimum threshold that must be attained to guard against false positive lesion detection. Conclusion: Low contrast resolution, or detectability, can be properly tested in a manner that is clinically relevant by measuring the contrast level of cold spheres within a Jaszczak phantom using pixel values within ROI's placed in the background and cold sphere regions. The measured contrast levels are then compared to a minimum threshold calculated using the Rose criterion and a CNRlesion = 4. The measured contrast levels must either meet or exceed this minimum threshold to prove acceptable lesion detectability. This research and development activity was performed by the authors while employed at West Physics Consulting, LLC. It is presented with the consent of West Physics, which has authorized the dissemination of the information and/or techniques described in the work

  7. Nanotechnology and nuclear medicine; research and preclinical applications.

    Science.gov (United States)

    Assadi, Majid; Afrasiabi, Kolsoom; Nabipour, Iraj; Seyedabadi, Mohammad

    2011-01-01

    The birth of nanotechnology in human society was around 2000 years ago and soon found applications in various fields. In this article, we highlight the current status of research and preclinical applications and also future prospects of nanotechnology in medicine and in nuclear medicine. The most important field is cancer. A regular nanotechnology training program for nuclear medicine physicians may be welcome. PMID:21761018

  8. Absorbed Doses to Patients in Nuclear Medicine

    International Nuclear Information System (INIS)

    The work with a Swedish catalogue of radiation absorbed doses to patients undergoing nuclear medicine investigations has continued. After the previous report in 1999, biokinetic data and dose estimates (mean absorbed dose to various organs and tissues and effective dose) have been produced for a number of substances: 11C- acetate, 11C- methionine, 18F-DOPA, whole antibody labelled with either 99mTc, 111In, 123I or 131I, fragment of antibody, F(ab')2 labelled with either 99mTc, 111In, 123I or 131I and fragment of antibody, Fab' labelled with either 99mTc, 111In, 123I or 131I. The absorbed dose estimates for these substances have been made from published biokinetic information. For other substances of interest, e.g. 14C-urea (children age 3-6 years), 14C-glycocholic acid, 14C-xylose and 14C-triolein, sufficient literature data have not been available. Therefore, a large number of measurements on patients and volunteers have been carried out, in order to determine the biokinetics and dosimetry for these substances. Samples of breast milk from 50 mothers, who had been subject to nuclear medicine investigations, have been collected at various times after administration of the radiopharmaceutical to the mother. The activity concentration in the breast milk samples has been measured. The absorbed dose to various organs and tissues and the effective dose to the child who ingests the milk have been determined for 17 different radiopharmaceuticals. Based on these results revised recommendations for interruption of breast-feeding after nuclear medicine investigations are suggested

  9. Discuss the Clinical Value About Nuclear Medicine Diagnosis of Primary Parathyroid Function%探讨核医学诊断原发性甲状旁腺功能亢进症的临床价值

    Institute of Scientific and Technical Information of China (English)

    张洋

    2015-01-01

    Objective To analyze the clinical value of diagnosis about the application of nuclear medicine in primary parathyroid function (PHPT). Methods The clinical diagnosis data of 9 patients in our hospital with PHPT were analyzed retrospectively. Results All patients with bone scintigraphy were present a metabolic bone disease, mtc 04-99, 99 MTC thyroid imaging-MIBI in two-phase nuclide imaging abnormal image part existed. Conclusion The application of nuclear medical imaging has important value for clinical diagnosis of PHPT.%目的:分析应用核医学对原发性甲状旁腺功能亢进症(PHPT)进行诊断的临床价值。方法选择我院收治的9例PHPT患者的临床诊断资料进行回顾性分析。结果所有患者的骨显像均呈现出代谢性骨病,99mTc04-甲状腺显像、99mTc-MIBI双时相核素显像部分有异常影像存在。结论应用核医学影像对PHPT进行临床诊断具有重要价值。

  10. Artificial neural networks in nuclear medicine

    International Nuclear Information System (INIS)

    An analysis of the accessible literature on the diagnostic applicability of artificial neural networks in coronary artery disease and pulmonary embolism appears to be comparative to the diagnosis of experienced doctors dealing with nuclear medicine. Differences in the employed models of artificial neural networks indicate a constant search for the most optimal parameters, which could guarantee the ultimate accuracy in neural network activity. The diagnostic potential within systems containing artificial neural networks proves this calculation tool to be an independent or/and an additional device for supporting a doctor's diagnosis of artery disease and pulmonary embolism. (author)

  11. Security in the nuclear medicine department

    International Nuclear Information System (INIS)

    The current threat from terrorism highlights the need for awareness of adequate security of radioactive sources by health bodies to prevent the opportunistic access to, theft of. or accidental loss of sources, together with stringent security measures in place to prevent the international misuse of radioactive sources as a weapon by unauthorised access. This presentation discusses the processes undertaken to ensure the safety and security of radioactive materials within the nuclear medicine department in line with current regulations and guidelines. These include risk assessments, security systems, audit trails, restricted access and personnel background checks

  12. Energy-coded processing in nuclear medicine

    International Nuclear Information System (INIS)

    A method for processing image data which takes into account the energy of each detected gamma-ray photon. Weighted spatial averaging of local detected count densities in radionuclide images can increase the visual detectability of abnormalities. In principle, the benefits of image processing in nuclear medicine can be increased by processing the image data in each interval of the detected photon spectrum using a procedure that is appropriate for the spatial resolution and statistical quality associated with that energy interval, and by combining energy-coded processed image components using generally energy-dependent weights. The potential gains in detection performance by implementation of such an approach are examined

  13. Nuclear medicine: dosimetric considerations: pregnancy and lactation

    International Nuclear Information System (INIS)

    Radiation exposure of pregnant woman in nuclear medicine is important from the point of view of radiological protection. In this report are presented the most relevant considerations for the internal dosimetry during pregnancy and lactation. The dose estimation to the mother and fetus during pregnancy can be made based in MIRD methodology with specific phantoms of the pregnant woman allowing the dose calculation in the first, second and third month of pregnancy, through the MIRDOSE software. The effective doses in infants and recommendations are also explained in this report

  14. Development of Scintillators in Nuclear Medicine.

    Science.gov (United States)

    Khoshakhlagh, Mohammad; Islamian, Jalil Pirayesh; Abedi, Seyed Mohammad; Mahmoudian, Babak

    2015-01-01

    High-quality image is necessary for accurate diagnosis in nuclear medicine. There are many factors in creating a good image and detector is the most important one. In recent years, several detectors are studied to get a better picture. The aim of this paper is comparison of some type of these detectors such as thallium activated sodium iodide bismuth germinate cesium activated yttrium aluminum garnet (YAG: Ce) YAP: Ce "lutetium aluminum garnet activated by cerium" CRY018 "CRY019" lanthanum bromide and cadmium zinc telluride. We studied different properties of these crystals including density, energy resolution and decay times that are more important factors affecting the image quality. PMID:26420984

  15. Development of Scintillators in Nuclear Medicine

    OpenAIRE

    Khoshakhlagh, Mohammad; Islamian, Jalil Pirayesh; Abedi, Seyed Mohammad; Mahmoudian, Babak

    2015-01-01

    High-quality image is necessary for accurate diagnosis in nuclear medicine. There are many factors in creating a good image and detector is the most important one. In recent years, several detectors are studied to get a better picture. The aim of this paper is comparison of some type of these detectors such as thallium activated sodium iodide bismuth germinate cesium activated yttrium aluminum garnet (YAG: Ce) YAP: Ce “lutetium aluminum garnet activated by cerium” CRY018 “CRY019” lanthanum br...

  16. Specification and acceptance testing of nuclear medicine equipment

    International Nuclear Information System (INIS)

    The purchase of nuclear medicine equipment is of prime importance in the operation of a clinical service. Failure to properly evaluate the potential uses of the instrumentation and the various operational characteristics of the equipment can often result in the purchase of inappropriate or inferior instruments. The magnitude of the purchase in terms of time and financial investments make it imperative that the purchase be approached in a systematic manner. Consideration of both the intended clinical functions and personnel requirements is important. It is necessary also to evaluate the ability of the equipment vendor to support the instrumentation after the purchase has been completed and the equipment installed in the clinical site. The desired specifications of the instrument characteristics should be stated in terms that can be verified by acceptance testing. The complexity of modern instrumentation and the sensitivity of it to the environment require the buyer to take into account the potential problems of controlling the temperature, humidity, and electrical power of the installation site. If properly and systematically approached, the purchase of new nuclear medicine instrumentation can result in the acquisition of a powerful diagnostic tool which will have a useful lifetime of many years. If not so approached, it may result in the expenditure of a large amount of money and personnel time without the concomitant return in useful clinical service. (author)

  17. The role of commercial nuclear pharmacy in the future practice of nuclear medicine.

    Science.gov (United States)

    Callahan, R J

    1996-04-01

    It has been estimated that today 70% to 80% of all radiopharmaceutical doses are dispensed through commercial nuclear pharmacy channels. These services are provided by the approximately 250 facilities in the United States, with some multisite corporations dispensing in excess of 20,000 unit-dose prescriptions per day. As pressures mount within health care institutions to reduce manpower, increase cost-effectiveness, increase participation in managed care contracts, and to seek outside vendors for many services that were previously provided in-house, the future role of the commercial nuclear pharmacy in the practice of nuclear medicine will only continue to increase. The essence of nuclear pharmacy practice is the dispensing of a full range of high quality radiopharmaceuticals in patient-specific unit doses. These doses must be delivered in a timely and cost effective manner, without compromising quality or patient safety. Commercial nuclear pharmacies have expanded to provide such varied functions as radiation safety and waste management, as well as consultative and marketing activities directed towards clinicians within a nuclear medicine practitioners own facility. In-service continuing education programs directed towards physicians and technologists are frequently offered by many commercial nuclear pharmacies. Changes in health care economics, merging and down-sizing in the hospital industry, and the overall impact of managed care on the viability of hospitals in general has resulted in slow growth, or even a small decline in the number of institutionally based nuclear pharmacists. As a result, nuclear medicine practitioners will be looking to the commercial nuclear pharmacies to meet a larger portion of their radiopharmaceutical needs, as well as to value added services, such as education and research and development. Specialized practice settings, such as nuclear cardiology and free-standing nuclear medicine clinics, are especially well suited to the services

  18. What does the gastro-enterologist expect from nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Claasen, M.

    1987-04-01

    The close cooperation between the specialists in nuclear medicine and gastroenterology is illustrated by several examples: The rate of bleeding sources within the small intestine, as detected by endoscopy, X-ray contrast studies of the (intestinal) lumen, and angiography, is not sufficiently high, but has been reported to be in a range of 50-100 per cent if labelled autologous erythrocytes are used, provided a bleeding rate of 1 ml/min. at least. Inflammatory areas in cases of Morbus Crohn (skip lesions) are of importance for the evaluation of functional impairments and thus for therapy. Modern studies using labelled granulocytes show a good correlation to endoscopic and histologic findings, both with regard to their spatial distribution and activity. Additional comparisons to the 'gold standard' endoscopy would be desirable. Treatment with monoclonal antibodies, which would act as a radiant 'destroyer' to exclusively destroy the tumour cells, could provide an important approach to therapy of inoperable tumours of the digestive tract. Nuclear medicine also is expected to provide valuable contributions to investigations of the bacterial flora of the small intestine and to coagulation studies in cases of liver failure. AT III-labelling has enabled the intrahepatic AT III-consumption to be detected in cases of liver failure. The gastro-enterologist expects nuclear medicine to cooperate in the solution of clinical and research problems of digestive diseases.

  19. Organization and regulation of nuclear medicine and radiotherapy in Argentina

    International Nuclear Information System (INIS)

    After describing the efforts carried out in Argentina during the decade of 1970 to consolidate nuclear medicine as a new clinical specialty, reference is made to the constitution, in 1979, of a Joint Advisory Committee on Nuclear Medicine and Radiotherapy integrated by members of the National Atomic Energy Commission and by members of the Public Health Ministry of the Nation, with the purpose to coordinate and plan said activities within the country. Two recommendations of said Advisory Committee are transcribed. The first one defines the different specialties of the professionals and technicians working in the new discipline. The second recommendation is referred to the regulations on ''Operation of Nuclear Medicine Units'', which set up different categories of medical establishments of the specialty (''unit'', ''service'' and ''center''), define their respective functions as well as the equipment and specialized personnel that they should be fitted with in each case, and institute the requirement to demonstrate having the corresponding academic and professional up-dating in the specialty to obtain the periodic revalidation of operation licences. (C.A.K.)

  20. Recruitment and Retention of Patients into Emergency Medicine Clinical Trials

    Science.gov (United States)

    Cofield, Stacey; Conwit, Robin; Barsan, William; Quinn, James

    2010-01-01

    The emergency medicine and pre-hospital environments are unlike any other clinical environments and require special consideration to allow the successful implementation of clinical trials. This article reviews the specific issues involved in Emergency Medicine Clinical Trials (EMCT), and provides strategies from emergency medicine and non-emergency medicine trials to maximize recruitment and retention. While the evidence supporting some of these strategies is deficient, addressing recruitment and retention issues with specific strategies will help researchers deal with these issues in their funding applications and in turn develop the necessary infrastructure to participate in emergency medicine clinical trials. PMID:21040112

  1. Quality management system in Nuclear Medicine

    International Nuclear Information System (INIS)

    Establishing Management Systems (QMS) in services Nuclear Medicine (NM) is a prerequisite for optimizing the efficacy and safety of diagnostic and therapeutic procedures of this specialty and increase steadily the quality of the services provide patients. Several international organizations such as the IAEA and scientific specialty societies (SNM, EBNM, etc) and national bodies stimulate and enhance their introduction; in our country is also a requirement of the National Nuclear Safety Centre (CNSN). Are presented in this paper, the main experiences of our country related to the implementation of QMS and developed tools for achieving this goal, such as: The QNUMED automated web environment for managing indicators and documentation format digital; b) The development of prototypes and models for the implementation of the documentation system; d) requirements applying QUANUM in conducting audits of quality management in local services including QUANUMTool tool; and f) human resource development issues in Quality Management. (author)

  2. The contribution of pulmonary nuclear medicine

    International Nuclear Information System (INIS)

    The contribution of pulmonary nuclear medicine was evaluated in 115 patients with interstitial pulmonary diseases (IPD). Ventilation study (V) with 81mKr or 133Xe, distribution of compliance in thoraco-pulmonary system (C) by 81mKr gas bolus inhalation method, perfusion study (Q) with 99mTc-MAA, 67Ga scintigraphy and an assessment of pulmonary epithelial permeability with 99mTc-DTPA aerosol were performed as nuclear medicine procedures. Pulmonary function test (%DLco, vital capacity, and functional residual capacity) and blood gas analysis were also examined. Abnormalities in V were larger than that in Q, which was high V/Q mismatch finding, in interstitial pneumonia. Correlation between V/Q mismatch and PaO2 was, therefore, not significant. %DLco was decreased in cases with larger V/Q mismatches. 67Ga accumulated in the early stage of interstitial pneumonia when CT or chest X-ray did not show any finding. %DLco was decreased in cases with strong accumulation of 67Ga. 67Ga might be useful to evaluate activity of the disease. Pulmonary epithelial permeability was assessed by 99mTc-DTPA inhalation study. This permeability became accelerated in idiopathic interstitial fibrosis and sarcoidosis. Pulmonary epithelial permeability may be useful as an indicator for epithelial cell injury. (author)

  3. Functional Measurements in Nuclear Medicine. Chapter 16

    International Nuclear Information System (INIS)

    The strength of nuclear medicine lies in using the tracer method to acquire information about how an organ is or is not functioning as it should. This modality, therefore, focuses on physiological organ function for diagnoses and not on anatomical information such as X ray computed tomography (CT) or magnetic resonance imaging. The three aspects involved in the process are: (i) choice of radioactive tracer, (ii) method of detection of the emissions from the tracer, and (iii) analysis of the results of the detection. The radioactive tracers on which nuclear medicine (or molecular imaging as it is increasingly being called) is based are designed to participate in or ‘trace’ a chosen function of the body. Their distribution is then found by detecting and locating the emissions, usually γ photons, of the radioactive tracer. The tracer may be involved in a metabolic process, such as iodine in the thyroid, or it may take part in a physiological process because of its physical make-up, such as macroaggregate of albumin (MAA) in the lungs

  4. Quality control of nuclear medicine instruments

    International Nuclear Information System (INIS)

    This document, which gives detailed guidance on the quality control of the various electronic instruments used for radiation detection and measurement in nuclear medicine, stems from the work of two Advisory Groups convened by the International Atomic Energy Agency (IAEA). A preliminary document, including recommended test schedules but lacking actual protocols for the tests, was drawn up by the first of these groups, meeting at the IAEA Headquarters in Vienna in 1979. A revised and extended version, incorporating recommended test protocols, was prepared by the second Group, meeting likewise in Vienna in 1982. This version is the model for the present text. The document should be of value to all nuclear medicine units, and especially to those in developing countries, in the initiation or revision of schemes for the quality control of their instruments. Its recommendations have provided the basis for instruction in two IAEA regional technical co-operation projects in the subject field, one initiated in 1981 for countries of Latin America and one initiated in 1982 for countries of Asia and the Pacific

  5. Recent developments and future trends in nuclear medicine instrumentation.

    Science.gov (United States)

    Zaidi, Habib

    2006-01-01

    Molecular imaging using high-resolution single-photon emission computed tomography (SPECT) and positron emission tomography (PET) has advanced elegantly and has steadily gained importance in the clinical and research arenas. Continuous efforts to integrate recent research findings for the design of different geometries and various detector technologies of SPECT and PET cameras have become the goal of both the academic comcameras have become the goal of both the academic community and nuclear medicine industry. As PET has recently become of more interest for clinical practice, several different design trends seem to have developed. Systems are being designed for "low cost" clinical applications, very high-resolution research applications (including small-animal imaging), and just about everywhere in-between. The development of dual-modality imaging systems has revolutionized the practice of nuclear medicine. The major advantage being that SPECT/PET data are intrinsically aligned to anatomical information from the X-ray computed tomography (CT), without the use of external markers or internal landmarks. On the other hand, combining PET with Magnetic Resonance Imaging (MRI) technology is scientifically more challenging owing to the strong magnetic fields. Nevertheless, significant progress has been made resulting in the design of a prototype small animal PET scanner coupled to three multichannel photomultipliers via optical fibers, so that the PET detector can be operated within a conventional MR system. Thus, many different design paths are being pursued--which ones are likely to be the main stream of future commercial systems? It will be interesting, indeed, to see which technologies become the most popular in the future. This paper briefly summarizes state-of-the art developments in nuclear medicine instrumentation. Future prospects will also be discussed. PMID:16696367

  6. Recent developments and future trends in nuclear medicine instrumentation

    International Nuclear Information System (INIS)

    Molecular imaging using high-resolution single-photon emission computed tomography (SPECT) and positron emission tomography (PET) has advanced elegantly and has steadily gained importance in the clinical and research arenas. Continuous efforts to integrate recent research findings for the design of different geometries and various detector technologies of SPECT and PET cameras have become the goal of both the academic community and nuclear medicine industry. As PET has recently become of more interest for clinical practice, several different design trends seem to have developed. Systems are being designed for ''low cost'' clinical applications, very high-resolution research applications (including small-animal imaging), and just about everywhere in-between. The development of dual-modality imaging systems has revolutionized the practice of nuclear medicine. The major advantage being that SPECT/PET data are intrinsically aligned to anatomical information from the X-ray computed tomography (CT), without the use of external markers or internal landmarks. On the other hand, combining PET with magnetic resonance imaging (MRI) technology is scientifically more challenging owing to the strong magnetic fields. Nevertheless, significant progress has been made resulting in the design of a prototype small animal PET scanner coupled to three multichannel photomultipliers via optical fibers, so that the PET detector can be operated within a conventional MR system. Thus, many different design paths are being pursued - which ones are likely to be the main stream of future commercial systems? It will be interesting, indeed, to see which technologies become the most popular in the future. This paper briefly summarizes state-of-the art developments in nuclear medicine instrumentation. Future prospects will also be discussed. (orig.)

  7. Redefining disease through advances in nuclear medicine

    International Nuclear Information System (INIS)

    Full text: Nuclear Imaging has progressed significantly in the last decade. The disease is being explored at receptor antigenic and biochemical level. The Molecular Imaging with tracers such as the 18-Fluro-Deoxy-Glucose (FDG), 11C-thymidine, 18-Fluro-Estradiol have enabled us to look into different aspects of disease. The FDG helps us in understanding aggressiveness of tumor and thereby survival of a cancer patient. It is enabling us to redefine disease at metabolic level leading to 'Metabolic Classification' of disease. The 18-Fluro-Estradiol scan is exploring breast cancer at receptor level and has enabled us to understand why some breast cancer patients do not respond to the hormone therapy. The 11C-Thymidine scan is able to image proliferative capacity of a tumor and thereby impact on the treatment approach. In addition to the field on oncology, recent advances in Nuclear Imaging are now providing valuable insights in understanding of various other human diseases. We are now redefining Alzheimer's disease and some of the psychiatric illnesses like Schizophrenia and Depression through the new Nuclear Imaging techniques. The years ahead will see extensive application of Nuclear Imaging technology in human disorders. Metabolic Classification of disease would bring out the processes underlying the causation and manifestation of diverse human disorders and help redefine the disease with the aim of more effective and less toxic personalized medicine

  8. Nuclear medicine for diagnostic evaluation of osteomyelitis in children

    International Nuclear Information System (INIS)

    Although skeletal scintiscanning has yielded results allowing an early diagnosis of osteomyelitis in children already at a stage prior to detection by X-ray radiography, reports have been published showing that there is quite a number of false negative findings obtained by nuclear medicine techniques, especially in newborns. The article here therefore reports a study on clinical validation of skeletal scintigraphy in case of suspected osteomyelitis in children. The results show that scintiscanning is a very sensitive method of detecting osteomyelitis in children, and also can be a very useful diagnostic tool for examination of newborns, provided the different anatomy of the skeleton in newborns is taken into account. (orig./MG)

  9. Nuclear Medicine in Pediatric and Adolescent Tumors.

    Science.gov (United States)

    Kiratli, Pınar Özgen; Tuncel, Murat; Bar-Sever, Zvi

    2016-07-01

    Nuclear medicine has an important role in the management of many cancers in pediatric age group with multiple imaging modalities and radiopharmaceuticals targeting various biological uptake mechanisms. 18-Flourodeoxyglucose is the radiotracer of choice especially in patients with sarcoma and lymphoma. (18)FDG-PET, for sarcoma and lymphomas, is proved to be superior to conventional imaging in staging and therapy response. Although studies are limited in pediatric population, (18)FDG-PET/CT has found its way through international guidelines. Limitations and strengths of PET imaging must be noticed before adapting PET imaging in clinical protocols. Established new response criteria using multiple parameters derived from (18)FDG-PET would increase the accuracy and repeatability of response evaluation. Current data suggest that I-123 metaiodobenzylguanidine (MIBG) remains the tracer of choice in the evaluation of neuroblastoma (NB) because of its high sensitivity, specificity, diagnostic accuracy, and prognostic value. It is valuable in determining the response to therapy, surveillance for disease recurrence, and in selecting patients for I-131 therapy. SPECT/CT improves the diagnostic accuracy and the interpretation confidence of MIBG scans. (18)FDG-PET/CT is an important complementary to MIBG imaging despite its lack of specificity to NB. It is valuable in cases of negative or inconclusive MIBG scans and when MIBG findings underestimate the disease status as determined from clinical and radiological findings. F-18 DOPA is promising tracer that reflects catecholamine metabolism and is both sensitive and specific. F-18 DOPA scintigraphy provides the advantages of PET/CT imaging with early and short imaging times, high spatial resolution, inherent morphologic correlation with CT, and quantitation. Regulatory and production issues currently limit the tracer's availability. PET/CT with Ga-68 DOTA appears to be useful in NB imaging and may have a unique role in selecting

  10. Evaluation of radiation protection in nuclear medicine diagnostic procedures

    International Nuclear Information System (INIS)

    This study conducted to evaluate the radiation protection in nuclear medicine diagnostic procedures in four nuclear medicine departments in Sudan. The evaluated procedures followed in these departments were in accordance with the standards, International Recommendations and code of practice for radiation protection in nuclear medicine. The evolution included the optimum design for diagnostic nuclear medicine departments, dealing with radioactive sources, quality assurance and quality control, training and responsibilities for radiation worker taking into account economic factors in Sudan. Evaluation of radiation protection procedures in diagnostic investigations was carried out by taken direct measurements of dose rate and the contamination level in some areas where radiation sources, radiation workers and public are involved. Designated questionnaires covered thirteen areas of radiation protection based on inspection check list for nuclear medicine prepared by the International Atomic Energy Agency (IAEA) and American Association of Physicist in Medicine (AAPM) were used in the evaluation. This questionnaire has been Filled by Radiation Protection Officer (RPO), nuclear medicine technologist, nuclear medicine specialist in the nuclear medicine departments. Four hospitals, two governmental hospital and two private hospitals, have been assisted, the assessment shows that although the diagnostic nuclear medicine department in Sudan are not applying a fully safety and radiation protection procedures, but the level of radiation dose and the contamination level were found within acceptable limits. The private hospital D scored the higher level of protection (85.25%) while the governmental hospital C scored the lower level of protection (59.02%). Finally, this study stated some recommendations that if implemented could improve the level of radiation protection in nuclear medicine department. One of the most important recommendations is that a proper radiation protection

  11. Nuclear medicine methods in the assessment of acupuncture effects: a short review

    OpenAIRE

    Deise Elisabete Souza; Bernardo Machado Rebello; Reginaldo de Carvalho Silva Filho; Raquel Terra Agostinho; Sohaku R. C. Bastos; Mario Bernardo-Filho

    2007-01-01

    The mechanisms of acupuncture are poorly understood. In consequence, numerous investigators have conducted clinical trials to test the efficacy of acupuncture in various conditions. We have used PubMed database system to evaluate the number of publications in acupuncture and nuclear medicine procedures in the period from 1964 to 2007, using the keywords: "nuclear medicine and acupuncture", "SPECT and acupuncture", "PET and acupuncture", "scintigraphy and acupuncture", "radionuclide and acupun...

  12. Can the benefits of nuclear medicine be used to justify low-level waste management risks?

    International Nuclear Information System (INIS)

    Risks associated with low-level radioactive waste (LLW) management must not be viewed in isolation, but rather within the context of the societal benefits derived from such activity. Nuclear medicine represents one of the most significant benefits that would disappear should LLW disposal become impossible. This presentation describes the vital role of modern nuclear medicine in clinical diagnosis, therapy, and research. Clear understanding of this valuable role is necessary for rational risk/benefit analysis of the LLW issue

  13. Radiological Justification for and Optimization of Nuclear Medicine Practices in Korea

    OpenAIRE

    Kim, Byung Il

    2016-01-01

    Nuclear medicine is a rapidly growing discipline that employs advanced novel hybrid techniques that provide unique anatomical and functional information, as well as targets for molecular therapy. Concomitantly, there has been an increase in the attention paid to medical radiation exposure. A radiological justification for the practice of nuclear medicine has been implemented mainly through referral guidelines based on research results such as prospective randomized clinical trials. The Intern...

  14. Summary results of an assessment of research projects in the Nuclear Medicine Research program

    International Nuclear Information System (INIS)

    In May 1987, OHER management requested the Office of Program Analysis (OPA) to conduct a peer review of the projects of the DOE Nuclear Medicine Research program. This was done using procedures and a quantitative methodology OPA developed for assessing DOE research programs. Sixty-three individual nuclear medicine projects were reviewed by seven panels; one panel on isotopes and radioisotopes, three on radiopharmacology, two on clinical feasibility, and one on instrumentation. Each panel consisted of five to ten knowledgeable reviewers. 5 figs

  15. Study of metrologic characteristics in activimeters used in Nuclear Medicine Centers in Colombia

    International Nuclear Information System (INIS)

    In our country currently there is a legislation that regulated de Nuclear Medicine practice, that establish the criteria about quality assurance in Nuclear Medicine and the justification to imparted to medical exposures. In this work includes some tests to the clinical approval in this type of instruments before to be used. The type of tests are linearity, geometric dependence and the energetic response and moreover to evaluate the total uncertainty during the work the physician using this equipment with radioactive sources. (author)

  16. Impact of nuclear medicine on the diagnosis and management of cardiovascular disease

    International Nuclear Information System (INIS)

    Recent advances in the methods of diagnostic cardiology have brought a change in emphasis toward noninvasive patient study. Nuclear Medicine techniques play an important part among noninvasive methods which enable diagnostic and therapeutic evaluation in the majority of patients with cardiac problems, without resorting to dangerous, painful and costly cardiac catheterization. Discussed are only a few of the myriad clinical applications which are rapidly making nuclear medicine techniques an integral part of the cardiologic diagnostic armamentarium

  17. Standardization of Administered Activities in Pediatric Nuclear Medicine: A Report of the First Nuclear Medicine Global Initiative Project, Part 2-Current Standards and the Path Toward Global Standardization.

    Science.gov (United States)

    Fahey, Frederic H; Bom, Henry Hee-Seung; Chiti, Arturo; Choi, Yun Young; Huang, Gang; Lassmann, Michael; Laurin, Norman; Mut, Fernando; Nuñez-Miller, Rodolfo; O'Keeffe, Darin; Pradhan, Prasanta; Scott, Andrew M; Song, Shaoli; Soni, Nischal; Uchiyama, Mayuki; Vargas, Luis

    2016-07-01

    The Nuclear Medicine Global Initiative (NMGI) was formed in 2012 and consists of 13 international organizations with direct involvement in nuclear medicine. The underlying objectives of the NMGI are to promote human health by advancing the field of nuclear medicine and molecular imaging, encourage global collaboration in education, and harmonize procedure guidelines and other policies that ultimately lead to improvements in quality and safety in the field throughout the world. For its first project, the NMGI decided to consider the issues involved in the standardization of administered activities in pediatric nuclear medicine. It was decided to divide the final report of this project into 2 parts. Part 1 was published in this journal in the spring of 2015. This article presents part 2 of the final report. It discusses current standards for administered activities in children and adolescents that have been developed by various professional organizations. It also presents an evaluation of the current practice of pediatric nuclear medicine specifically with regard to administered activities as determined by an international survey of 313 nuclear medicine clinics and centers from 29 countries. Lastly, it provides recommendations for a path toward global standardization of the administration of radiopharmaceuticals in children. PMID:27033894

  18. Clinical Epidemiology, Evidence Based Medicine and Good Clinical Practice Guidelines vs. Clinical Method?

    OpenAIRE

    Luis Alberto Corona Martínez; Mercedes Fonseca Hernández

    2009-01-01

    Evidence Based Medicine, as a trend or approach to the medical practice nowadays, and the use of Good Clinical Practice Guidelines in the assistance activities are core elements that contribute to improve the professional practice and the decision making process in diagnosis and therapy; but they do not substitute the professional method for patients assistance: the clinical method. The purpose of this article is to analyze the role of clinical epidemiology, evidence based medicine and good c...

  19. Nuclear medicine achievements in Grenoble (France)

    International Nuclear Information System (INIS)

    The author reviews the contribution of the scientific teams of CENG (Grenoble nuclear research center) to nuclear medicine. CENG opened in 1958. At that time most research was dedicated to the understanding of the biological effects of radiation because of the cold war and its increased risk of nuclear disaster. In the sixties, the easy access to a broad range of artificial radio-nuclides, triggered the development of radio-pharmacology. Iodine-131 was used to study the thyroid gland, iron-59 and chromium-51 were used to study bone pathology and the kinetics of iron in the human body. Rubidium-86 and xenon-139 gave good results for the study of blood circulation. Iodine-123 and Krypton-81m were produced at the ISN cyclotron as soon as 1971. Around 1960 radiotherapy began to be performed in Grenoble specialized hospitals, where cobalt-60, iridium-192 and cesium-137 sources were intensively used. Today 3 teams worked on a project to adapt the proton emission tomograph that is due to be installed in a Grenoble hospital, to the study of the human brain. (A.C.)

  20. Stereoscopic full aperture imaging in nuclear medicine

    Directory of Open Access Journals (Sweden)

    Sergio G. Strocovsky

    2011-06-01

    Full Text Available Images of planar scintigraphy and single photon emission computerized tomography (SPECT used in nuclear medicine are often low quality. They usually appear to be blurred and noisy. This problem is due to the low spatial resolution and poor sensitivity of the acquisition technique with the gamma camera (GC. Other techniques, such as coded aperture imaging (CAI reach higher spatial resolutions than GC. However, CAI is not frequently used for imaging in nuclear medicine, due to the decoding complexity of some images and the difficulty in controlling the noise magnitude. Summing up, the images obtained through GC are low quality and it is still difficult to implement CAI technique. A novel technique, full aperture Imaging (FAI, also uses gamma ray-encoding to obtain images, but the coding system and the method of images reconstruction are simpler than those used in CAI. In addition, FAI also reaches higher spatial resolution than GC. In this work, the principles of FAI technique and the method of images reconstruction are explained in detail. The FAI technique is tested by means of Monte Carlo simulations with filiform and spherical sources. Spatial resolution tests of GC versus FAI were performed using two different source-detector distances. First, simulations were made without interposing any material between the sources and the detector. Then, other more realistic simulations were made. In these, the sources were placed in the centre of a rectangular prismatic region, filled with water. A rigorous comparison was made between GC and FAI images of the linear filiform sources, by means of two methods: mean fluence profile graphs and correlation tests. Finally, three-dimensional capacity of FAI was tested with two spherical sources. The results show that FAI technique has greater sensitivity (>100 times and greater spatial resolution (>2.6 times than that of GC with LEHR collimator, in both cases, with and without attenuating material and long and

  1. Aspects on caring in pediatric nuclear medicine

    International Nuclear Information System (INIS)

    During nuclear medicine examinations, the child is exposed to more or less distressful and/or painful procedures. Many children find it difficult to understand why they have to go through a specific examination. In addition, the surrounding is unfamiliar with heavy technical equipment. The first experience is crucial for the child's future attitudes towards hospitals in general and diagnostic procedures in particular. Apart from having child-focused personnel, there are many ways to improve the situation, and I will focus on four corner-stones. 1. Information; 2. Pain relief; 3. Diversion; 4. Sedation. 1. Information should be addressed directly to the child as well as to the parents. Today, children use the computer already from an early age, and we have initiated the use of Internet as a medium for child-adapted information. With texts, photos and multimedia on an interactive site we are able to reach also quite young children as well as children with difficulties to understand only written parts. Pain relief for vein puncture should always be considered. We use the topical anaesthetic EMLA cream in newborns (> 2.800 g) as well as in teenagers. Trained staff is another condition for high success rate in performing vein punctures, and continuous education vouches for that. 3. Diversion (distraction) is a general term for directing the child's attention from the procedures or to make time pass faster. Age adapted diversions should be readily available for every child. Apart from soap bubbles, toys, books, music and videos there are other possibilities, such as 'Guided imagery', a way of day-dreaming initiated by personnel trained in this method. 4. Sedation should be used when other options are not sufficient. For conscious sedation we use midazolam, administered either iv, intranasal, rectally or orally. The nurses/technologists handle the routines. In nuclear medicine, 4-5 % of the children, mostly between 1-3 years old, are sedated either for fear of vein

  2. The impact of nuclear science on medicine

    CERN Document Server

    Kraft, G

    1999-01-01

    From the very beginning, i.e. from the discovery of the natural radioactivity by H. Becquerel and the production of radium by M. Curie, nuclear physics had a strong impact on medicine: Radioactive sources were immediately made use of in tumor therapy long before the action mechanisms of ionizing radiation were understood. The invention of the tracer technique by G. Hevesy opened a new field for the study of chemokinetics as well as for the in-vivo measurement of various organ functions. In the percutane tumor therapy hadrons like neutrons, pions, protons and heavier ions were tested. Presently, proton therapy is a great success and is spreading all over the world. The new techniques of target-conform treatment using heavy ions for an improved tumor targeting and control represent the latest great improvement of radiation tumor therapy.

  3. What is generally meant by nuclear medicine

    International Nuclear Information System (INIS)

    The work field of nuclear medicine students are defined and include 'in vivo' and 'in vitro' radioactive isotopes research, radio-therapy, radio-pharmacology, and the study of irradiation effects. Therapy treatments detailed include applications to hyperthyroids, thyroid cancer and polycythaemia. Definitions are also given of the radioactive half-lives of radionuclides, both physical and biological, used in medical research. Details are given of the relatively new technique of radioactive generators, sometimes known as 'radioactive cows', of which 99m Tc is widely used at present as its half-life (6 hours) is suitable for medical work. Tabular information is given for radio-pharmaceuticals with special relevance to specific organs of the body, e.g. thyroid, kidney, lung, pancreas, etc. (G.C.)

  4. Directory of computer users in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Henne, R.L.; Erickson, J.J.; McClain, W.J.; Kirch, D.L.

    1977-01-01

    The directory is composed of two major divisions, a Users' section and a Vendors' section. The Users' section consists of detailed installation descriptions and indexes to these descriptions. A typical description contains the name, address, type, and size of the institution as well as names of persons to contact. Following the hardware descriptions are listed the type of studies for which the computers are utilized, including the languages used, the method of output and an estimate of how often the study is performed. The Vendors' section contains short descriptions of current commercially available nuclear medicine systems as supplied by the vendors themselves. In order to reduce the amount of obsolete data and to include new institutions in future updates of the directory, a user questionnaire is included. (HLW)

  5. Directory of computer users in nuclear medicine

    International Nuclear Information System (INIS)

    The directory is composed of two major divisions, a Users' section and a Vendors' section. The Users' section consists of detailed installation descriptions and indexes to these descriptions. A typical description contains the name, address, type, and size of the institution as well as names of persons to contact. Following the hardware descriptions are listed the type of studies for which the computers are utilized, including the languages used, the method of output and an estimate of how often the study is performed. The Vendors' section contains short descriptions of current commercially available nuclear medicine systems as supplied by the vendors themselves. In order to reduce the amount of obsolete data and to include new institutions in future updates of the directory, a user questionnaire is included

  6. Pathogenesis and role of nuclear medicine

    International Nuclear Information System (INIS)

    The means by which replication of viruses takes place is explained, as it helps in the understanding of how viruses spread in the blood and how antiretroviral drugs work. The most important viruses, from a health care workers point of view, are hepatitis B and C and human immunodefiency virus (HIV). Whether nuclear medicine has a role to play in the diagnosis of these viruses, and the oportunistic infections that go with them, is debatable. Several radiopharmaceuticals are extremely sensitive for infection and tumor imaging but lack specificity. Patients' treatment is often not based on the outcome of the investigation but rather on preset protocols. AIDS patients are put on prophylactic antibiotic treatment as protection against infections such as toxoplasmosis and pneumocystis carinii pneumonia and there is a poor prognosis for AIDS patients with tumors (Au)

  7. Nuclear medicine training and practice in the Czech Republic.

    Science.gov (United States)

    Kamínek, Milan; Koranda, Pavel

    2014-08-01

    Nuclear medicine in the Czech Republic is a full specialty with an exclusive practice. Since the training program was organized and structured in recent years, residents have had access to the specialty of nuclear medicine, starting with a two-year general internship (in internal medicine or radiology). At present, nuclear medicine services are provided in 45 departments. In total, 119 nuclear medicine specialists are currently registered. In order to obtain the title of Nuclear Medicine Specialist, five years of training are necessary; the first two years consist of a general internship in internal medicine or radiology. The remaining three years consist of training in the nuclear medicine specialty itself, but includes three months of practice in radiology. Twenty-one physicians are currently in nuclear medicine training and a mean of three specialists pass the final exam per year. The syllabus is very similar to that of the European Union of Medical Specialists (UEMS), namely concerning the minimum recommended numbers for diagnostic and therapeutic procedures. In principle, the Czech law requires continuous medical education for all practicing doctors. The Czech Medical Chamber has provided a continuing medical education (CME) system. Other national CMEs are not accepted in Czech Republic. PMID:24867257

  8. Nuclear medicine training and practice in the Czech Republic

    Energy Technology Data Exchange (ETDEWEB)

    Kaminek, Milan; Koranda, Pavel [University Hospital Olomouc, Department of Nuclear Medicine, Olomouc (Czech Republic)

    2014-08-15

    Nuclear medicine in the Czech Republic is a full specialty with an exclusive practice. Since the training program was organized and structured in recent years, residents have had access to the specialty of nuclear medicine, starting with a two-year general internship (in internal medicine or radiology). At present, nuclear medicine services are provided in 45 departments. In total, 119 nuclear medicine specialists are currently registered. In order to obtain the title of Nuclear Medicine Specialist, five years of training are necessary; the first two years consist of a general internship in internal medicine or radiology. The remaining three years consist of training in the nuclear medicine specialty itself, but includes three months of practice in radiology. Twenty-one physicians are currently in nuclear medicine training and a mean of three specialists pass the final exam per year. The syllabus is very similar to that of the European Union of Medical Specialists (UEMS), namely concerning the minimum recommended numbers for diagnostic and therapeutic procedures. In principle, the Czech law requires continuous medical education for all practicing doctors. The Czech Medical Chamber has provided a continuing medical education (CME) system. Other national CMEs are not accepted in Czech Republic. (orig.)

  9. Nuclear medicine training and practice in the Czech Republic

    International Nuclear Information System (INIS)

    Nuclear medicine in the Czech Republic is a full specialty with an exclusive practice. Since the training program was organized and structured in recent years, residents have had access to the specialty of nuclear medicine, starting with a two-year general internship (in internal medicine or radiology). At present, nuclear medicine services are provided in 45 departments. In total, 119 nuclear medicine specialists are currently registered. In order to obtain the title of Nuclear Medicine Specialist, five years of training are necessary; the first two years consist of a general internship in internal medicine or radiology. The remaining three years consist of training in the nuclear medicine specialty itself, but includes three months of practice in radiology. Twenty-one physicians are currently in nuclear medicine training and a mean of three specialists pass the final exam per year. The syllabus is very similar to that of the European Union of Medical Specialists (UEMS), namely concerning the minimum recommended numbers for diagnostic and therapeutic procedures. In principle, the Czech law requires continuous medical education for all practicing doctors. The Czech Medical Chamber has provided a continuing medical education (CME) system. Other national CMEs are not accepted in Czech Republic. (orig.)

  10. Cellular dosimetry in nuclear medicine imaging: training

    International Nuclear Information System (INIS)

    The radionuclides used in nuclear medicine imaging emit not only diagnostically useful photons, but also energy electron emissions, responsible for dose heterogeneity at the cellular level. The mean dose delivered to the cell nucleus by electron emissions of 99mTc, 123I, 111In, 67Ga, and 201Tl, has been calculated, for the cell nucleus, a cytoplasmic and a cell membrane distribution of radioactivity. This model takes into account both the self-dose which results from the radionuclide located in the target cell, and the cross-dose, which comes from the surrounding cells. The results obtained by cellular dosimetry (Dcel) have been compared with those obtained with conventional dosimetry (Dconv), by assuming the same amount of radioactivity per cell. Cellular dosimetry shows, for a cytoplasmic and a cell membrane distributions of radioactivity, that the main contribution to the dose to the cell nucleus, comes from the surrounding cells. On the other hand, for a cell nucleus distribution of radioactivity, the self-dose is not negligible and may be the main contribution. The comparison between cellular and conventional dosimetry shows that Dcel/Dconv ratio ranges from 0.61 and O.89, in case of a cytoplasmic and a cell membrane distributions of radioactivity, depending on the radionuclide and cell dimensions. Thus, conventional dosimetry slightly overestimates the mean dose to the cell nucleus. On the other hand, Dcel/Dconv ranges from 1.1 to 75, in case of a cell nucleus distribution of radioactivity. Conventional dosimetry may strongly underestimates the absorbed dose to the nucleus, when radioactivity is located in the nucleus. The study indicates that in nuclear medicine imaging, cellular dosimetry may lead to a better understanding of biological effects of radiopharmaceuticals. (authors)

  11. Display of nuclear medicine imaging studies

    International Nuclear Information System (INIS)

    Nuclear medicine imaging studies involve evaluation of a large amount of image data. Digital signal processing techniques have introduced processing algorithms that increase the information content of the display. Nuclear medicine imaging studies require interactive selection of suitable form of display and pre-display processing. Static imaging study requires pre-display processing to detect focal defects. Point operations (histogram modification) along with zoom and capability to display more than one image in one screen is essential. This album mode of display is also applicable to dynamic, MUGA and SPECT data. Isometric display or 3-D graph of the image data is helpful in some cases e.g. point spread function, flood field data. Cine display is used on a sequence of images e.g. dynamic, MUGA and SPECT imaging studies -to assess the spatial movement of tracer with time. Following methods are used at the investigator's discretion for inspection of the 3-D object. 1) Display of orthogonal projections, 2) Display of album of user selected coronal/ sagital/ transverse orthogonal slices, 3) Display of three orthogonal slices through user selected point, 4) Display of a set of orthogonal slices generated in the user-selected volume, 5) Generation and display of 3-D shaded surface. 6) Generation of volume data and display along with the 3-D shaded surface, 7) Side by side display orthogonal slices of two 3-D objects. Displaying a set of two-dimensional slices of a 3-D reconstructed object through shows all the defects but lacks the 3-D perspective. Display of shaded surface lacks the ability to show the embedded defects. Volume display -combining the 3-D surface and gray level volume data is perhaps the best form of display. This report describes these forms of display along with the theory. (author)

  12. Practice of nuclear medicine in a developing country

    International Nuclear Information System (INIS)

    For more than a half a century nuclear medicine is contributing in the field of medicine. Still nuclear medicine is not widely available in many countries. Especially in developing countries due to many a reasons nuclear medicine could not flourish in that way. Availability of radioisotope, high cost of instrument and sophistication of the branch are the three main reasons behind. Even the countries where nuclear medicine is functioning for quite a long time, the facilities for proper function are still not adequate. Training of manpower, maintenance of instruments, regular supply of isotopes and kit and cost effectiveness are some of the major problems. We have seen some fast developments in nuclear medicine in last few decades. Development of gamma detecting systems with SPECT, positron emission detector (PET), supported computer technology and introduction of some newer radiopharmaceuticals for functional studies are few of the examples. The developing countries also have a problem to go on parallel with these rapid development of nuclear medicine in other part of the world. In last few decades we have also witnessed development of CT, MRI, Ultrasound and other imaging modalities as our competitor. Specially for developing countries these have posed as a major challenge for nuclear medicine. A better understanding between developed and developing nations is the key point of todays ultimate success in any sector. For real development of nuclear medicine and to give the majority of the people the benefit of nuclear medicine a better and more active co-operation is needed between all the countries. The paper presents the difficulties and some practical problems of practicing nuclear medicine in a developing country. And also appeals for global co-operation to solve the problems for better interest of the subject

  13. Proceedings of the Korean Society Nuclear Medicine Spring Meeting 1999

    International Nuclear Information System (INIS)

    This proceedings contains articles of 1999 spring meeting of the Korean Society Nuclear Medicine. It was held on May 21, 1999 in Chonju, Korea. The subject title of proceedings is radioisotope therapy using Re-188. Radiopharmaceuticals have been used for the diagnosis and treatment of human diseases, mostly for the diagnostic purposes in nuclear medicine. (Yi, J. H.)

  14. Nuclear medicine and articulation prosthesis of the lower limbs

    International Nuclear Information System (INIS)

    Several nuclear medicine procedures can help the surgeons in the diagnosis of the complications of articulations prosthesis of the lower limbs, in particular in case of torpid infection. Even if the diagnosis remains uncertain, the indications and the interpretation of these procedures benefit of a close collaboration between nuclear medicine specialist and clinicians. (author)

  15. Source Book of Educational Materials for Nuclear Medicine.

    Science.gov (United States)

    Pijar, Mary Lou, Comp.; Lewis, Jeannine T., Comp.

    The contents of this sourcebook of educational materials are divided into the following sections: Anatomy and Physiology; Medical Terminology; Medical Ethics and Department Management; Patient Care and Medical Decision-Making; Basic Nuclear Medicine; Diagnostic in Vivo; Diagnostic in Vitro; Pediatric Nuclear Medicine; Radiation Detection and…

  16. Contamination monitor as a nuclear stethoscope for community nuclear medicine

    International Nuclear Information System (INIS)

    A portable contamination monitor has been modified for use as an in vivo counting probe. The evaluation by physical parameters and clinical studies shows its suitability for a variety of diagnostic studies. The correlation equations for thyroid uptake measurement have been worked out for whole range of values. Its use as a versatile nuclear stethoscope is envisaged. (author)

  17. Nuclear medicine in Uzbekistan: Past, present and future

    International Nuclear Information System (INIS)

    Full text: Uzbekistan is one of the biggest countries in Middle Asia with a population of about 26.5 million. Nuclear Medicine in Uzbekistan has a long history. The first Nuclear Medicine Departments were organized in the 1950s and spread quickly in the 1960's when the number grew to 22 nuclear medicine centres in whole country. They were equipped with probe renogram, scanners, multiprobes and anger gamma cameras. As far as the Nuclear Medicine Department of Republic Specialized Center of Surgery is concerned, it was organized in 1976 and the first equipment of the institution was the anger gamma camera, ''Nuclear Chicago,'' as well as the probe renogram and multiple probes. At that time, the spectre of Nuclear Medicine examinations included: renoscintigraphy with I-131 hippuran, thyroid scintigraphy with I-131, MUGA, hepatic scintigraphy with sulphur colloid and HIDA, lung perfusion and ventilation, lymphoscintigraphy of low extremities, radiography (investigation of central hemodynamic), dynamic brain perfusion, bone scintigraphy of bone transplant, selective radionuclide angiography (examination of peripheral microcirculation) and phleboscintigraphy of low extremities. Unfortunately, the situation changed during the first years of Uzbekistan independence (1991) due to the economic situation. The number of Nuclear Medicine Departments decreased to 10. However, the NM Department of Republic Specialised Center of Surgery never stopped its clinical and research work. Nonetheless, the number of examinations performed significantly dropped. A new era of Nuclear Medicine in Uzbekistan was started in 2000 when the IAEA approved the TC project ''Introduction of SPECT in Uzbekistan''. With the great help of IAEA, the Republic Specialised Center of Surgery received a single head SPECT gamma camera (E-CAM Siemens). Furthermore, under the next TC project ''Implementation of NM in Uzbekistan,'' the same Center received a second SPECT dual head gamma camera (Nucline Spirit

  18. Career prospects for graduating nuclear medicine residents: survey of nuclear medicine program directors.

    Science.gov (United States)

    Harolds, Jay A; Guiberteau, Milton J; Metter, Darlene F; Oates, M Elizabeth

    2013-08-01

    There has been much consternation in the nuclear medicine (NM) community in recent years regarding the difficulty many NM graduates experience in securing initial employment. A survey designed to determine the extent and root causes behind the paucity of career opportunities was sent to all 2010-2011 NM residency program directors. The results of that survey and its implications for NM trainees and the profession are presented and discussed in this article. PMID:23763875

  19. Nuclear medicine - the state of the art of nuclear medicine in Europe

    International Nuclear Information System (INIS)

    The present proceedings of the European Nuclear Medicine Congress 1990 contain the opening addresses and the oral presentations of the meeting. The topics were as follows: Methods and basics (52 papers), cardiology (12 papers), neurology (13 papers), pulmonology (2 papers), gastroenterology (9 papers), nephrology (7 papers), osteology (8 papers), endocrinology (7 papers), pediatrics (5 papers), and oncology (12 papers). An author index and a subject index is found as a supplement to these proceedings. (MG) With 182 figs., 92 tabs

  20. Critical appraisal of diagnostic studies in nuclear medicine

    International Nuclear Information System (INIS)

    The conceptual ideas of evidence based critical appraisal of diagnostic studies are described in this survey. In this context special attention is given to biases in study design such as verification- as well as information-bias limiting the validity of diagnostic studies. The practice of critical appraisal is demonstrated in an application to an example of a nuclear medicine scenario. The impact of evidence based medicine on nuclear medicine as a diagnostic discipline is discussed in detail. (orig.)

  1. Pulmonary nuclear medicine: Techniques in diagnosis of lung disease

    International Nuclear Information System (INIS)

    This book presents papers on the application of nuclear medicine to the diagnosis of lung diseases. Topics considered include lung physiology and anatomy, radiopharmaceuticals in pulmonary medicine, pulmonary embolism, obstructive pulmonary disease, diffuse infiltrative lung disease, pneumoconioses, tumor localization scans in primary lung tumors, the interactions of heart diseases and lung diseases on radionuclide tests of lung anatomy and function, radionuclide imaging in pediatric lung diseases, and future possibilities in pulmonary nuclear medicine

  2. Evidence-based integrative medicine in clinical veterinary oncology.

    Science.gov (United States)

    Raditic, Donna M; Bartges, Joseph W

    2014-09-01

    Integrative medicine is the combined use of complementary and alternative medicine with conventional or traditional Western medicine systems. The demand for integrative veterinary medicine is growing, but evidence-based research on its efficacy is limited. In veterinary clinical oncology, such research could be translated to human medicine, because veterinary patients with spontaneous tumors are valuable translational models for human cancers. An overview of specific herbs, botanics, dietary supplements, and acupuncture evaluated in dogs, in vitro canine cells, and other relevant species both in vivo and in vitro is presented for their potential use as integrative therapies in veterinary clinical oncology. PMID:25174902

  3. Assessing and Reducing Exposures to Nuclear Medicine Staff

    International Nuclear Information System (INIS)

    Nuclear medicine involves the handling of unsealed radiation sources. Occupational monitoring in nuclear medicine, thus, includes assessment of both external irradiation of the body and internal exposure due to inhalation or ingestion of radioactive substances. When appropriate radiation protection measures are applied, the annual effective dose to nuclear medicine staff is low (around 2–3 mSv). However, hand doses can be very high and can even exceed the regulatory limit for skin equivalent dose, without workers being aware of it. The paper presents the main results of the European Atomic Energy Community’s Seventh Framework Programme project, Optimization of Radiation Protection of Medical Staff (ORAMED), within the field of extremity dosimetry of nuclear medicine staff, and proposes recommendations to improve radiation protection in occupational exposure in nuclear medicine. (author)

  4. Japanese consensus guidelines for pediatric nuclear medicine. Part 1. Pediatric radiopharmaceutical administered doses (JSNM pediatric dosage card). Part 2. Technical considerations for pediatric nuclear medicine imaging procedures

    International Nuclear Information System (INIS)

    The Japanese Society of Nuclear Medicine has recently published the consensus guidelines for pediatric nuclear medicine. This article is the English version of the guidelines. Part 1 proposes the dose optimization in pediatric nuclear medicine studies. Part 2 comprehensively discusses imaging techniques for the appropriate conduct of pediatric nuclear medicine procedures, considering the characteristics of imaging in children. (author)

  5. Scintigraphic instruments and techniques in nuclear medicine

    International Nuclear Information System (INIS)

    The development of new radiopharmaceuticals, cyclotron-produced radionuclides and improvement of detector, scanner and gamma camera characteristics have enable a remarkable recent progress in scintigraphic techniques for organ visualization and functional studies. Using a variety of techniques, positron cameras, section scanners, gamma holography, tomographic imaging appear to be playing an increasing important role. Data processing techniques, for example image processing and three dimensional reconstruction have significantly increased their impact. The principal research work and advances in technique achieved up to 1972 are summarized and the subjects which have been further exploited are outlined. The main section comprises references and abstracts of articles from scientific journals and conference proceedings (191 articles and 221 papers mentioned) for the period 1972-1975 to illustrate advances in this domain: Excerpta Medica (Nuclear Medicine) Abstract Journals and Nuclear Science Abstracts (1972-1975) were used as abstracting publications. This survey is completed with an index of authors and subject-matters. Eleven thesis are mentionned in an appendix

  6. Instrumentation and procedural problems in nuclear medicine

    International Nuclear Information System (INIS)

    In this chapter, the nuclear instrumentation problems, procedural errors, and resultant scintiphoto artifacts that might be encountered before, during, and after a nuclear medicine scan are discussed. In practice, whenever a scintiphoto is of unacceptable quality or contains an evident artifact, it generally is discarded, corrective actions are taken and, if possible the study is repeated. Instead of discarding the unacceptable scan, however, a notebook of all of these imaging artifacts could be compiled and made accessible to all personnel in the department. This artifact identification notebook is especially useful in a teaching institution in which technologists or residents are being trained. There is no better learning axion than that ''you learn by your mistakes.'' It is much easier on a department for rookies to learn from the mistakes of others, as cited in the artifact notebook, than for each individual to repeat all the common mistakes made by those who came before. It also becomes easier to identify or recognize the cause of many artifacts by referencing the manual or notebook

  7. New nuclear medicine gamma camera systems

    International Nuclear Information System (INIS)

    The acquisition of the Open E.CAM and DIACAM gamma cameras by Makati Medical Center is expected to enhance the capabilities of its nuclear medicine facilities. When used as an aid to diagnosis, nuclear medicine entails the introduction of a minute amount of radioactive material into the patient; thus, no reaction or side-effect is expected. When it reaches the particular target organ, depending on the radiopharmaceutical, a lesion will appear as a decrease (cold) area or increase (hot) area in the radioactive distribution as recorded byu the gamma cameras. Gamma camera images in slices or SPECT (Single Photon Emission Computer Tomography), increase the sensitivity and accuracy in detecting smaller and deeply seated lesions, which otherwise may not be detected in the regular single planar images. Due to the 'open' design of the equipment, claustrophobic patients will no longer feel enclosed during the procedure. These new gamma cameras yield improved resolution and superb image quality, and the higher photon sensitivity shortens imaging acquisition time. The E.CAM, which is the latest generation gamma camera, is featured by its variable angle dual-head system, the only one available in the Philipines, and the excellent choice for Myocardial Perfusion Imaging (MPI). From the usual 45 minutes, the acquisition time for gated SPECT imaging of the heart has now been remarkably reduced to 12 minutes. 'Gated' infers snap-shots of the heart in selected phases of its contraction and relaxation as triggered by ECG. The DIACAM is installed in a room with access outside the main entrance of the department, intended specially for bed-borne patients. Both systems are equipped with a network of high performance Macintosh ICOND acquisition and processing computers. Added to the hardware is the ICON processing software which allows total simultaneous acquisition and processing capabilities in the same operator's terminal. Video film and color printers are also provided. Together

  8. The practice of nuclear medicine in the Philippines

    International Nuclear Information System (INIS)

    The advent of nuclear medicine in the early 1940's came with the use of radioiodine in the study of thyroid physiology and eventual treatment of hyperthyroidism. Instrumentation to detect radionuclides introduced into the human body, and the production of various radiopharmaceuticals as tracers or as therapy agents provided the impetus for the rapid development of nuclear medicine as a distinct specialty. In the Philippines, nuclear medicine formally began in 1956 with the establishment of the Radioisotope Laboratory at the Philippine General Hospital. Acquisition of nuclear instrumentation by various institutions, training of medical staff and personnel, sourcing of radiopharmaceuticals proceeded thereafter

  9. Nuclear medicine methods in the assessment of acupuncture effects: a short review

    International Nuclear Information System (INIS)

    The mechanisms of acupuncture are poorly understood. In consequence, numerous investigators have conducted clinical trials to test the efficacy of acupuncture in various conditions. We have used PubMed database system to evaluate the number of publications in acupuncture and nuclear medicine procedures in the period from 1964 to 2007, using the keywords: 'nuclear medicine and acupuncture', 'SPECT and acupuncture, 'PET and acupuncture', 'scintigraphy and acupuncture, 'radionuclide and acupuncture', 'radiopharmaceutical and acupuncture', 'radioisotope and acupuncture' and 99mTc and acupuncture'. Some papers published in English language were selected and a short review is presented The analysis of the number of publications shows that when a method is well accepted by the scientific community, as the methods used in nuclear medicine, the interest in the development of research increases. Moreover, important findings are presented when the nuclear medicine image is used to evaluate the effect of the acupuncture. (author)

  10. Monte Carlo techniques in diagnostic and therapeutic nuclear medicine

    International Nuclear Information System (INIS)

    Monte Carlo techniques have become one of the most popular tools in different areas of medical radiation physics following the development and subsequent implementation of powerful computing systems for clinical use. In particular, they have been extensively applied to simulate processes involving random behaviour and to quantify physical parameters that are difficult or even impossible to calculate analytically or to determine by experimental measurements. The use of the Monte Carlo method to simulate radiation transport turned out to be the most accurate means of predicting absorbed dose distributions and other quantities of interest in the radiation treatment of cancer patients using either external or radionuclide radiotherapy. The same trend has occurred for the estimation of the absorbed dose in diagnostic procedures using radionuclides. There is broad consensus in accepting that the earliest Monte Carlo calculations in medical radiation physics were made in the area of nuclear medicine, where the technique was used for dosimetry modelling and computations. Formalism and data based on Monte Carlo calculations, developed by the Medical Internal Radiation Dose (MIRD) committee of the Society of Nuclear Medicine, were published in a series of supplements to the Journal of Nuclear Medicine, the first one being released in 1968. Some of these pamphlets made extensive use of Monte Carlo calculations to derive specific absorbed fractions for electron and photon sources uniformly distributed in organs of mathematical phantoms. Interest in Monte Carlo-based dose calculations with β-emitters has been revived with the application of radiolabelled monoclonal antibodies to radioimmunotherapy. As a consequence of this generalized use, many questions are being raised primarily about the need and potential of Monte Carlo techniques, but also about how accurate it really is, what would it take to apply it clinically and make it available widely to the medical physics

  11. Special monitoring in nuclear medicine; Monitoreo especial en medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Beltran, C.C.; Puerta, J.A.; Morales, J. [Asociacion Colombiana de Proteccion Radiologica (Colombia)]. e-mail: ccbeltra@gmail.com

    2006-07-01

    Colombia counts with around 56 centers of Nuclear Medicine, 70 Nuclear Doctors and more of 100 Technologists in this area. The radioisotopes more used are the {sup 131} I and the {sup 99m} Tc. The radiological surveillance singular in the country is carried out for external dosimetry, being the surveillance by incorporation of radioactive materials very sporadic in our media. Given the necessity to implement monitoring programs in the incorporation of radionuclides of the occupationally exposed personnel, in the routine practice them routine of Nuclear Medicine, it was implemented a pilot program of Special Monitoring with two centers of importance in the city of Medellin. This program it was carried out with the purpose of educating, to stimulate and to establish a program of reference monitoring with base in the National Program of Monitoring in the radionuclides Incorporation that serves like base for its application at level of all the services of Nuclear Medicine in the country. This monitoring type was carried out with the purpose of obtaining information on the work routine in these centers, form of manipulation and dosage of the radionuclides, as well as the administration to the patient. The application of the program was carried out to define the frequency of Monitoring and analysis technique for the implementation of a program of routine monitoring, following the recommendations of the International Commission of Radiological Protection. For their application methods of activity evaluation were used in urine and in 7 workers thyroid, of those which only two deserve an analysis because they presented important activities. The measures were carried out during one month, every day by means in urine samples and to the most critic case is practiced two thyroid measures, one in the middle of the period and another when concluding the monitoring. To the other guy is practiced an activity count in thyroid when concluding the monitoring period. The obtained

  12. What You Should Know About Pediatric Nuclear Medicine and Radiation Safety

    Science.gov (United States)

    ... Radiation Safety www.imagegently.org What is nuclear medicine? Nuclear medicine uses radioactive isotopes to create pictures of the human body. ... help doctors find health problems and plan treatment. Nuclear medicine tests can find infections, birth defects, injuries and ...

  13. Characterization of iodinated adrenomedullin derivatives suitable for lung nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Fu Yan; Letourneau, Myriam; Chatenet, David [Laboratoire d' etudes moleculaires et pharmacologiques des peptides, INRS-Institut Armand-Frappier, Ville de Laval, Qc, H7V 1B7 (Canada); Dupuis, Jocelyn [Research Center, Montreal Heart Institute, Montreal, Qc (Canada); Department of Medicine, University of Montreal, Montreal, Qc (Canada); Fournier, Alain, E-mail: alain.fournier@iaf.inrs.ca [Laboratoire d' etudes moleculaires et pharmacologiques des peptides, INRS-Institut Armand-Frappier, Ville de Laval, Qc, H7V 1B7 (Canada)

    2011-08-15

    Introduction: We have recently demonstrated the effectiveness of 99m-technetium adrenomedullin (AM) as a new molecular lung imaging agent that could provide significant advantages for the diagnosis and follow-up of disorders affecting the pulmonary circulation such as pulmonary embolism and pulmonary hypertension. Having the possibility to conjugate the targeting molecule with different radionuclides would offer more flexibility and potential advantages depending on clinical situations. Since various iodine isotopes are currently used in nuclear medicine and in pharmacological studies, we have evaluated which iodination method should be privileged in order to produce a good iodinated AM-derived nuclear medicine agent. Methods: Synthetic AM was labeled with iodine through chemical and lactoperoxidase oxidation methods. Position of the iodine atom on the peptide was determined by MALDI-TOF mass spectrometry analysis following cyanogen bromide cleavage and carboxypeptidase Y digestion. Binding affinity of iodinated AM analogues was evaluated by competition and saturation binding experiments on dog lung preparations. Results: In this study, we demonstrated that, upon lactoperoxidase oxidation, iodination occurred at Tyr{sup 1} and that this radioligand retained higher binding affinity and specificity over preparations obtained through chemical oxidation. Conclusions: These results emphasize the fact that even a small chemical modification, i.e. iodination, might deeply modify the pharmacological profile of a compound and support observations that the C-terminal tail of human AM plays an important role in the AM receptor binding process. Consequently, incorporation of a radionuclide to produce an AM-based nuclear medicine agent should privilege the N-terminus of the molecule.

  14. Semiconductor arrays for nuclear medicine imaging

    International Nuclear Information System (INIS)

    Full text: Gamma-ray imaging of an injected radiotracer is used in nuclear medicine to determine organ function or locate the site of pathology such as cancer. Current gamma cameras use scintillation detectors with analog position estimation and are characterized by poor spatial resolution (0.4 cm) and poor energy resolution (11% FWHM at 140 keV). Energy resolution is important for suppressing the effects of Compton scattering in tissue. Single photon emission computed tomography (SPECT) is used to generate a three-dimensional representation of the source distribution. Another technique, positron emission tomography (PET), images the annihilation radiation from a positron emitter but is more costly than SPECT and is less widely available. Arrays of semiconductor detectors have long been considered an attractive alternative to scintillators for use in gamma cameras. Semiconductor detectors have excellent energy resolution and can be fabricated into large arrays of small pixel size and thus good spatial resolution using photolithography techniques. The best semiconductor detectors are Si and Ge, but these are less attractive for nuclear medicine purposes because of low gamma-ray stopping power or the need for expensive cryogenics. Most interest has centered on room-temperature semiconductor detectors such as CdTe and HgI2. However, until now, the main use of semiconductors in nuclear medicine has been as detectors in probes used to locate radiotracer-labelled tumors or other pathology at surgery or endoscopy. There are a number of reasons why a practical semiconductor camera has not yet been developed: semiconductor detectors are very expensive. Large detector areas (0.1 - 0.2 square meter) will be required for a camera. Electronics for reading out as many as a million separate detector pixels must be provided. Room-temperature semiconductor detectors suffer from charge carrier trapping that limits their useful efficiency. Current multibore collimators must trade off

  15. The current status and future perspectives of nuclear medicine in Korea.

    Science.gov (United States)

    Lee, Myung Chul; Oh, So Won; Chung, June-Key; Lee, Dong Soo

    2010-06-01

    Since the introduction of nuclear medicine in 1959, Korea accomplished a brilliant development in terms of both clinical practice and research activities, which was mainly due to the dedication of nuclear medicine specialists, consisting of physicians, technicians, and scientists, and strong support from the Korean Government. Now, Korea has 150 medical institutes, performing approximately 561,000 nuclear imaging procedures and 11.6 million in vitro studies in 2008, and ranked fourth in the number of presentations at the Annual Meeting of the Society of Nuclear Medicine (SNM) in 2008. The successful progress in this field has allowed Korea to focus on the international promotion of nuclear medicine, especially in the developing and underdeveloped countries. In consequence, the Asian Regional Cooperative Council for Nuclear Medicine (ARCCNM) was established in 2001, and Seoul hosted the 9th Congress of the World Federation of Nuclear Medicine and Biology (WFNMB) in 2006. In the future, Korea will strive to sustain its rate of advancement in the field and make every effort to share its progress and promote the exchange of scientific information at the international level. PMID:25013521

  16. The Current Status and Future Perspectives of Nuclear Medicine in Korea

    International Nuclear Information System (INIS)

    Since the introduction of nuclear medicine in 1959, Korea accomplished a brilliant development in terms of both clinical practice and research activities, which was mainly due to the dedication of nuclear medicine specialists, consisting of physicians, technicians, and scientists, and strong support from the Korean Government. Now, Korea has 150 medical institutes, performing approximately 561,000 nuclear imaging procedures and 11.6 million in vitro studies in 2008, and ranked fourth in the number of presentations at the Annual Meeting of the Society of Nuclear Medicine (SNM) in 2008. The successful progress in this field has allowed Korea to focus on the international promotion of nuclear medicine, especially in the developing and underdeveloped countries. In consequence, the Asian Regional Cooperative Council for Nuclear Medicine (ARCCNM) was established in 2001, and Seoul hosted the 9th Congress of the World Federation of Nuclear Medicine and Biology (WFNMB) in 2006. In the future, Korea will strive to sustain its rate of advancement in the field and make every effort to share its progress and promote the exchange of scientific information at the international level.

  17. Nuclear medicine imaging and therapy: gender biases in disease.

    Science.gov (United States)

    Moncayo, Valeria M; Aarsvold, John N; Alazraki, Naomi P

    2014-01-01

    Gender-based medicine is medical research and care conducted with conscious consideration of the sex and gender differences of subjects and patients. This issue of Seminars is focused on diseases for which nuclear medicine is part of routine management and for which the diseases have sex- or gender-based differences that affect incidence or pathophysiology and that thus have differences that can potentially affect the results of the relevant nuclear medicine studies. In this first article, we discuss neurologic diseases, certain gastrointestinal conditions, and thyroid conditions. The discussion is in the context of those sex- or gender-based aspects of these diseases that should be considered in the performance, interpretation, and reporting of the relevant nuclear medicine studies. Cardiovascular diseases, gynecologic diseases, bone conditions such as osteoporosis, pediatric occurrences of some diseases, human immunodeficiency virus-related conditions, and the radiation dose considerations of nuclear medicine studies are discussed in the other articles in this issue. PMID:25362232

  18. New radionuclide generator systems for use in nuclear medicine

    International Nuclear Information System (INIS)

    A current emphasis in nuclear medicine is to better match the physical lifetime of the radionuclides used in vivo for diagnosis and treatment to the biological lifetime of the diagnostic procedure or to minimize radiation dose to areas other than those to be treated. In many cases the biological lifetime is on the order of minutes. Since the direct production of radionuclides with half lives of minutes requires the user to be near a suitable reactor or accelerator, this study was undertaken to produce short-lived radionuclides indirectly. If a long-lived radionuclide decays into a short-lived radionuclide, quick separation of the daughter activity from the parent enables the user to have a short-lived daughter while freeing him from the constraint of proximity to a cyclotron. Systems where a short-lived daughter is separated from a long-lived parent are called radionuclide generators. Two generator systems were developed for use in nuclear medicine, one in diagnostic work and the other for therapeutic work. The yield and breakthrough characteristics were within the limits required to minimize unnecessary radiation exposure in patients. Two parent radionuclides were produced using 4He beams available from medium energy cyclotrons. The yield was high enough to produce generators that would be useful in clinical applications

  19. Contemporary nuclear medicine imaging of neuroendocrine tumours

    International Nuclear Information System (INIS)

    Neuroendocrine tumours (NETs) are rare, heterogeneous, and often hormonally active neoplasms. Nuclear medicine (NM) imaging using single photon- and positron-emitting radiopharmaceuticals allows sensitive and highly specific molecular imaging of NETs, complementary to anatomy-based techniques, such as computed tomography (CT) and magnetic resonance imaging (MRI). Somatostatin-receptor scintigraphy is a whole-body imaging technique widely used for diagnosis, staging and restaging of NETs. The increasing availability of hybrid single-photon emission CT (SPECT)/CT cameras now offers superior accuracy for localization and functional characterization of NETs compared to traditional planar and SPECT imaging. The potential role of positron-emission tomography (PET) tracers in the functional imaging of NETs is also being increasingly recognized. In addition to 2-[18F]-fluoro-2-deoxy-D-glucose (FDG), newer positron-emitting radiopharmaceuticals such as 18F-dihydroxyphenylalanine (DOPA) and 68Ga-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) peptides, show promise for the future. This article will summarize the role of current and emerging radiopharmaceuticals in NM imaging of this rare but important group of tumours.

  20. Nuclear medicine and the nursing mother

    International Nuclear Information System (INIS)

    Many radiopharmaceuticals may be detected in breast milk, but differ from other drugs in that for diagnostic purposes they are used in tracer quantities and do not produce demonstrable pharmacological changes in mother or infant. Patients may also be given non-radioactive drugs to induce changes in the distribution of the radiopharmaceuticals and some of these, too, appear in milk (e.g. frusemide, potassium perchlorate, iodides, and cholecystokinin). Iodides are selectively concentrated in breast milk, and some consider them contra-indicated during lactation. A period of interruption of breast feeding, expression of milk, and reduction of close contact with the infant is usually recommended for mothers who have a nuclear medicine investigation. The inconvenience and disadvantages of interrupting breast feeding have to be balanced against the potential risk to the infant: the prolonged interruption of feeding advocated for some agents is often impracticable. Interruption for 24 hours for sup(99m)Tc compounds is excessive for doses used in Britain. Twelve hours leaves a wide range of safety for pertechnetate. No interruption is needed for sup(99m)Tc-macroaggregated albumin and sup(99m)Tc-diethylenetriamine-penta-acetic acid in order to remain below one tenth of the annual limit of intake. (U.K.)

  1. Nuclear medicine at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Atkins, H.L.

    1976-01-01

    The Nuclear Medicine Program at the Brookhaven National Laboratory seeks to develop new materials and methods for the investigation of human physiology and disease processes. Some aspects of this research are related to basic research of how radiopharmaceuticals work. Other aspects are directed toward direct applications as diagnostic agents. It is likely that cyclotron-produced positron emitting nuclides will assume greater importance in the next few years. This can be attributed to the ability to label biologically important molecules with high specific activity without affecting biological activity, using /sup 11/C, /sup 13/N, and /sup 15/O. Large quantities of these short-lived nuclides can be administered without excessive radiation dose and newer instrumentation will permit reconstructive axial tomography, providing truly quantitative display of distribution of radioactivity. The /sup 122/Xe-/sup 122/I generator has the potential for looking at rapid dynamic processes. Another generator, the /sup 68/Ge-/sup 68/Ga generator produces a positron emitter for the use of those far removed from cyclotrons. The possibilities for /sup 68/Ga radiopharmaceuticals are as numerous as those for /sup 99m/Tc diagnostic agents.

  2. Specific filters applied in nuclear medicine services

    Energy Technology Data Exchange (ETDEWEB)

    Ramos, Vitor S.; Crispim, Verginia R., E-mail: verginia@con.ufrj.b [Coordenacao dos Programas de Pos-Graduacao de Engenharia (PEN/COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Nuclear; Brandao, Luis E.B. [Instituto de Engenharia Nuclear (IEN/CNEN-RJ) Rio de Janeiro, RJ (Brazil)

    2011-07-01

    In Nuclear Medicine, radioiodine, in various chemical forms, is a key tracer used in diagnostic practices and/or therapy. Due to its high volatility, medical professionals may incorporate radioactive iodine during the preparation of the dose to be administered to the patient. In radioactive iodine therapy doses ranging from 3.7 to 7.4 GBq per patient are employed. Thus, aiming at reducing the risk of occupational contamination, we developed a low cost filter to be installed at the exit of the exhaust system where doses of radioactive iodine are fractionated, using domestic technology. The effectiveness of radioactive iodine retention by silver impregnated silica [10%] crystals and natural activated carbon was verified using radiotracer techniques. The results showed that natural activated carbon is effective for I{sub 2} capture for a large or small amount of substrate but its use is restricted due to its low flash point (150 deg C). Besides, when poisoned by organic solvents, this flash point may become lower, causing explosions if absorbing large amounts of nitrates. To hold the CH{sub 3}I gas, it was necessary to increase the volume of natural activated carbon since it was not absorbed by SiO{sub 2} + Ag crystals. We concluded that, for an exhaust flow range of (306 {+-} 4) m{sup 3}/h, a double stage filter using SiO{sub 2} + Ag in the first stage and natural activated carbon in the second is sufficient to meet radiological safety requirements. (author)

  3. Nuclear medicine imaging in the evaluation of endocrine hypertension

    Directory of Open Access Journals (Sweden)

    Punit Sharma

    2012-01-01

    Full Text Available Endocrine hypertension forms a small (< 5% but curable subset of patients with hypertension. Common endocrine causes of hypertension include pheochromocytoma, Cushing′s syndrome, primary hyperaldosteronism, and thyroid disorders. Nuclear medicine imaging plays an important role in evaluation of patients with endocrine hypertension. It has established role in patients of pheochromocytoma/paraganglioma, Cushing′s syndrome, aldosteronism, and thyroid disorders. We present a brief overview of role of nuclear medicine imaging in endocrine hypertension. Development of newer radiotracers might further broaden the role of nuclear medicine in these patients.

  4. History and Perspectives of Nuclear Medicine in Bangladesh

    OpenAIRE

    Raihan Hussain

    2016-01-01

    Bangladesh is one of the smaller states in Asia. But it has a long and rich history of nuclear medicine for over sixty years. The progress in science and technology is always challenging in a developing country. In 1958, work for the first Nuclear Medicine facility was commenced in Dhaka in a tin-shed known as ‘Radioisotope Centre’ and was officially inaugurated in 1962. Since the late 50s of the last century nuclear medicine in Bangladesh has significantly progressed through the years in its...

  5. Current status of respiratory nuclear medicine

    International Nuclear Information System (INIS)

    . Newly developed radiotracers include L-3-123I-α-methyl-tyrosine for evaluating amino acid metabolism of lung cancer on SPECT scanner, 99mTc-labeled surfactant B for evaluating pulmonary surfactant system, Cu-DTS for imaging hypoxic tumor cells, and 18F-fluorocaptopril for evaluating the lung distribution of pulmonary angiotension converting enzyme. These will contribute to the further advancement and development of expiratory nuclear medicine. (author)

  6. Complementary and Alternative Medicine Cancer Clinical Trials

    Science.gov (United States)

    ... Introduction Cancer CAM Clinical Trials Introduction What are clinical trials? A clinical trial is one of the final ... and effective. What are the different types of clinical trials? Treatment trials test new treatments (like a new ...

  7. Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine

    Energy Technology Data Exchange (ETDEWEB)

    Coulot, J

    2003-08-07

    Monte Carlo techniques are involved in many applications in medical physics, and the field of nuclear medicine has seen a great development in the past ten years due to their wider use. Thus, it is of great interest to look at the state of the art in this domain, when improving computer performances allow one to obtain improved results in a dramatically reduced time. The goal of this book is to make, in 15 chapters, an exhaustive review of the use of Monte Carlo techniques in nuclear medicine, also giving key features which are not necessary directly related to the Monte Carlo method, but mandatory for its practical application. As the book deals with therapeutic' nuclear medicine, it focuses on internal dosimetry. After a general introduction on Monte Carlo techniques and their applications in nuclear medicine (dosimetry, imaging and radiation protection), the authors give an overview of internal dosimetry methods (formalism, mathematical phantoms, quantities of interest). Then, some of the more widely used Monte Carlo codes are described, as well as some treatment planning softwares. Some original techniques are also mentioned, such as dosimetry for boron neutron capture synovectomy. It is generally well written, clearly presented, and very well documented. Each chapter gives an overview of each subject, and it is up to the reader to investigate it further using the extensive bibliography provided. Each topic is discussed from a practical point of view, which is of great help for non-experienced readers. For instance, the chapter about mathematical aspects of Monte Carlo particle transport is very clear and helps one to apprehend the philosophy of the method, which is often a difficulty with a more theoretical approach. Each chapter is put in the general (clinical) context, and this allows the reader to keep in mind the intrinsic limitation of each technique involved in dosimetry (for instance activity quantitation). Nevertheless, there are some minor

  8. Training in nuclear medicine: Based on the recommendations of IAEA/WHO Seminar, 8-12 August 1988, Vienna, Austria

    International Nuclear Information System (INIS)

    Nuclear Medicine is defined as a clinical specialty that utilizes the radionuclides for diagnosis, therapy and medical research. The radionuclides are used as unsealed sources of radioactivity. The diagnostic applications include both in vivo and in vitro uses of radioisotopes. There is hardly any medical research which does not use radioactive compounds. Only clinical research is considered within the purview of nuclear medicine. The Recommendations of IAEA/WHO seminar reviewed the needs of training in nuclear medicine mainly for the physicians with special emphasis on the needs of the developing countries

  9. Cytokine medicines in clinical practice: current issues.

    Science.gov (United States)

    Barnes, Theresa; Moots, Robert J; Goodacre, John

    2005-10-21

    Cytokine medicines have been licensed for the treatment of rheumatoid arthritis since 2000. The rheumatology community has accrued a large amount of experience in the use of these medications. This experience has led to the development of guidelines for their use that include ongoing vigilance for long term adverse events and efficacy using the Biologics Register. Delivery of these expensive therapies has prompted extensive system developments within rheumatology. The cytokine medicines have provided important tools to probe the pathogenesis of rheumatoid and other inflammatory diseases. Further cytokine medicines, in various stages of development, are on the horizon and continue to stimulate excitement within this fast expanding field. PMID:16188452

  10. Proceedings of the 6.Brazilian Meeting on Nuclear Medicine

    International Nuclear Information System (INIS)

    Several subjects on nuclear medicine are presented. The use of scintiscanning in heart diseases, neoplasms, etc. is emphasized. Radioisotope preparation techniques and labelling of compounds used in radioassays are described. (M.A.C.)

  11. Proceedings of the 7. Brazilian Meeting on Nuclear Medicine

    International Nuclear Information System (INIS)

    Subjects about nuclear medicine are discussed. Researchs concerning the use of radioisotopes as tracers in several diseases are presented. The use of radioisotopes in diagnosis are emphasized. (M.A.C.)

  12. Requirements of radiation protection and safety for nuclear medicine services

    International Nuclear Information System (INIS)

    The requirements of radiation protection and safety for nuclear medicine services are established. The norms is applied to activities related to the radiopharmaceuticals for therapeutics and 'in vivo' diagnostics purposes. (M.C.K.)

  13. Metabolic radiopharmaceutical therapy in nuclear medicine; Terapia metabolica mediante radiofarmacos en medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Reguera, L.; Lozano, M. L.; Alonso, J. C.

    2016-08-01

    In 1986 the National Board of Medical Specialties defined the specialty of nuclear medicine as a medical specialty that uses radioisotopes for prevention, diagnosis, therapy and medical research. Nowadays, treatment with radiopharmaceuticals has reached a major importance within of nuclear medicine. The ability to treat tumors with radiopharmaceutical, Radiation selective therapy has become a first line alternative. In this paper, the current situation of the different therapies that are sued in nuclear medicine, is reviewed. (Author)

  14. Role of Nuclear Medicine in the cardiac resinchronization therapy

    Energy Technology Data Exchange (ETDEWEB)

    Brandao, Simone Cristina Soares, E-mail: simonecordis@yahoo.com.br [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil); Giorgi, Maria Clementina Pinto; D' Orio, Silvana Angelina; Meneghetti, Jose Claudio [Instituto do Coracao (InCor/FM/USP), Sao Paulo, SP (Brazil)

    2011-10-15

    Cardiac resynchronization therapy (CRT) emerged as one of the most promising approaches in the treatment of cardiac dyssynchrony in heart failure patients' refractory to medical treatment. However, despite very promising clinical and functional results, individual response analyses show that a significant number of patients do not respond to treatment. The role of nuclear medicine and molecular imaging in the selection of CRT candidates by the assessment of cardiac dyssynchrony, myocardial viability, myocardial perfusion and blood flow and sympathetic cardiac activity has been discussed in this review. The potential utilization of this tool to improve the comprehension of detrimental effects of dyssynchrony on cardiac function and the evaluation and monitoring of the response to CRT were also considered. Other molecular targets that characterize glucose and fatty acid metabolism, apoptosis, angiotensin converting enzyme activity and angiogenesis that can be evaluated with this technique were described. (author)

  15. Evaluations of Molecular Nuclear Medicine in pediatric urgencies

    International Nuclear Information System (INIS)

    Several diagnostic procedures of Molecular Nuclear Medicine are considered in first choice in clinical evaluation of patients with different illnesses. So, the gammagraphy is the diagnostic form more sensitive to detect alterations of the perfusion on organs and systems such as bones, heart, brain, lungs or kidneys. Also is possible to identify, localize, evaluate the activity of inflammatory processes such as cellulitis, arthritis, osteomyelitis, the abscesses and several primary or metastatic tumours before each other diagnostic technique. In this work is treated about the importance of treatments with radioactive materials have been an important reappearance in last years since with the present capacity to localize specifically intracellular processes (for example, synthesis of DNA) new gateways are opened to research which in coming years would be of great utility. (Author)

  16. Role of Nuclear Medicine in the cardiac resinchronization therapy

    International Nuclear Information System (INIS)

    Cardiac resynchronization therapy (CRT) emerged as one of the most promising approaches in the treatment of cardiac dyssynchrony in heart failure patients' refractory to medical treatment. However, despite very promising clinical and functional results, individual response analyses show that a significant number of patients do not respond to treatment. The role of nuclear medicine and molecular imaging in the selection of CRT candidates by the assessment of cardiac dyssynchrony, myocardial viability, myocardial perfusion and blood flow and sympathetic cardiac activity has been discussed in this review. The potential utilization of this tool to improve the comprehension of detrimental effects of dyssynchrony on cardiac function and the evaluation and monitoring of the response to CRT were also considered. Other molecular targets that characterize glucose and fatty acid metabolism, apoptosis, angiotensin converting enzyme activity and angiogenesis that can be evaluated with this technique were described. (author)

  17. Developments in digital computer implementation in nuclear medicine imaging

    International Nuclear Information System (INIS)

    The usefulness of a digital computer system for acquisition, manipulation and display of nuclear medicine or other medical two-dimensional images is enhanced by fast data acquisition of 80,000 cps in list mode (128 x 128) and 300,000 cps in histogram mode (64 x 64) with 3 μsec pulse pair resolution and dual isotope handling capabilities. Speed and ease of operation are important developments which lead to practical clinical application of research developments such as brain and heart blood-flow studies, Fresnel hologram reconstruction, three-dimensional reconstruction from multiple camera views, and display of functional images such as lung, heart, and kidney uptake and clearance rates

  18. Radiopharmaceuticals in nuclear medicine: evolution and present status

    International Nuclear Information System (INIS)

    A general overview of radiopharmaceuticals and their uses in nuclear medicine is presented. A brief history is outlined followed by the current status of the radiopharmaceuticals employed in the various branches of medicine such as neurology, cardiology, oncology, G.I. system and skeletal system. Important radiopharmaceutical preparations used in radionuclide therapy are described. (author). 58 refs., 1 tab., 2 figs

  19. Occupational exposure in nuclear medicine in Portugal in the 1999-2003 period

    International Nuclear Information System (INIS)

    The annual doses received by the staff of nuclear medicine departments from public hospitals and private clinics and evaluated by the Individual Monitoring Service of the Radiological Protection and Nuclear Safety Dept. (DPRSN) of the Nuclear and Technological Inst. (ITN) in Portugal, in the 5 y period from 1999 to 2003, are analysed and presented in this paper. In the 1999-2003 period, ITN-DPRSN monitored on an average 462 workers from nuclear medicine departments, which represents 6% of the 8000 workers of the medical field (approximately). The medical sector represents 80-85% of all the monitored population in Portugal. The professions of the monitored workers at nuclear medicine departments were identified by the respective departments as administrative, auxiliary, medical doctor, nuclear medicine technician, nurse, pharmacist and physicist. This information was collected at the onset of the monitoring and was updated over the last 3 y. The annual whole-body doses evaluated in the period 1999-2003 were used to derive the distribution of workers by dose intervals for every profession. The respective annual average doses and annual collective doses, as well as, the total average and total collective doses for the nuclear medicine sector were also determined and are presented. Internal radiation hasn't been monitored. (authors)

  20. Computers in Nuclear Medicine. Chapter 12

    International Nuclear Information System (INIS)

    In 1965, Gordon Moore, a co-founder of Intel, said that new memory chips have twice the capacity of prior chips, and that new chips are released every 18 to 24 months. This statement has become known as Moore’s law. Moore’s law means that memory size increases exponentially. More generally, the exponential growth of computers has applied not only to memory size, but also to many computer capabilities, and since 1965, Moore’s law has remained remarkably accurate. Further, this remarkable growth in capabilities has occurred with a steady decrease in price. Anyone who has even a little appreciation of exponential growth realizes that exponential growth cannot continue indefinitely. However, the history of computers is littered with ‘experts’ who have prematurely declared the end of Moore’s law. The quotation at the beginning of this section indicates that future growth of computers has often been underestimated. The exponential growth of computer capabilities has a very important implication for the management of a nuclear medicine department. The growth in productivity of the staff of a department is slow, especially when compared to the growth in capabilities of a computer. This means that whatever decision was made in the past about the balance between staff and computers is now out of date. A good heuristic is: always apply more computer capacity and less people to a new task. Or stated more simply, hardware is ‘cheap’, at least with respect to what you learned in training or what you decided last time you considered the balance between hardware and ‘peopleware’

  1. The role and indications of nuclear medicine in dentistry

    OpenAIRE

    Majid Reza Mokhtari; Fateme Farazi

    2010-01-01

    The role and indications of nuclear medicine in dentistry(a review article). Nuclear medicine and radioactive tracers have considerable application in dental research,because they provide one of the few practical methods for studying the limited metabolic activities of bones and teeth. The ease with which minute amounts of these radioactive materials may be accurately measured and distinguished from the mass of inert element in the tooth is particularly valuable. They are useful in s...

  2. Nuclear medicine in the assessment of differentiated thyroid cancer

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, G.-C. [Nuclear Medicine Department, Nottingham City Hospital, Nottingham (United Kingdom)], E-mail: gaylerutherford@doctors.org.uk; Franc, B. [Department of Radiology, Nuclear Medicine Section, University of California, San Francisco, CA (United States); O' Connor, A. [Nuclear Medicine Department, Nottingham City Hospital, Nottingham (United Kingdom)

    2008-04-15

    Despite modern multi-modality treatment, 10-30% of patients treated for differentiated thyroid cancer (DTC) ultimately develop local recurrence or metastatic disease. These malignancies are frequently slow-growing and secondary surgical resection is often undertaken along with radioactive iodine treatment. Correlation of radiological imaging with nuclear medicine studies is essential for individualized treatment planning, and to optimize this management. Radiologists should be familiar with the interpretation of various nuclear medicine studies used to image differentiated thyroid neoplasms.

  3. Nuclear medicine in the assessment of differentiated thyroid cancer

    International Nuclear Information System (INIS)

    Despite modern multi-modality treatment, 10-30% of patients treated for differentiated thyroid cancer (DTC) ultimately develop local recurrence or metastatic disease. These malignancies are frequently slow-growing and secondary surgical resection is often undertaken along with radioactive iodine treatment. Correlation of radiological imaging with nuclear medicine studies is essential for individualized treatment planning, and to optimize this management. Radiologists should be familiar with the interpretation of various nuclear medicine studies used to image differentiated thyroid neoplasms

  4. Nuclear Medicine Techniques in Haematological Research: Our Experience

    International Nuclear Information System (INIS)

    Abstract Nuclear diagnostic techniques have revolutionized medicine in its different specialties, among them hematology. This is, by the more relevant routine procedures of diagnostic as well as by future trends in this field, in-vivo research and clinical applications at the biochemical level. We report a part of our experience by the use in vitro and in vivo established nuclear medicine techniques, in evaluating hematological disease for clinical research that will lead to the basic research. The first study is megaloblastic anemia in which we report a prospective study from Tunisia, northern Africa, of 478 patients with megaloblastic anemia recruited over three years period. Etiologic investigation using cobalamin and folates measurements and the Schilling test revealed that folate deficiency was very uncommon and that 95% of patients had cobalamin deficiency that was the consequence of pernicious anemia (PA) in 87%. Patients with PA had a median age at presentation of 45.5 years with 21.5% of cases occurring in patients younger than 30 years. Patients less than 20 years old should be specifically investigated for genetic defect in cobalamin absorption. In the second study, the red cell mass was determined following labeling the red blood cells with either sodium radiochromate (51Cr) and the measurement of Plasma Volume is based on dilution of the injected radioiodine (125I)-labeled human serum albumin in the blood circulation (2,3). It is important to make this differentiation, thus our patients will fulfilled the criteria of the Polycythemia Vera Study Group, and therefore we will be able to evaluate serum VEGF levels in patients with Polycythemia Vera, secondary polycythemia and idiopatic polycythemia in an attempt to investigate the involvement and significance of this cytokine in these haematological disorders.

  5. Nuclear medicine techniques for the study of breast cancer

    International Nuclear Information System (INIS)

    In conclusion, the currently available data, which have mainly been obtained in th last 5 years at various centres including our own, seem to favour the introduction of nuclear medine techniques in clinical practice for the diagnostic and prognostic evaluation of breast carcinoma. However, to fully define the role of these techniques we believe good-quality studies should be conducted on selected, homogeneous case series and be aimed at the solution of precise diagnostic problems (small tumours, early stages, diagnostic suspicion without a palpable breast mass, etc.). Only then will it be possible to obtain a concrete idea of the diagnostic reliability of these methods in clinical situations, where more accurate diagnostic tools are urgently awaited. With regard to the radiopharmaceuticals that might be proposed and employed, we would recommend curbing the proliferation of new agents and devoting more attention to the validation of those of proven utility, taking into account the problem of cost. In our opinion the currently available gamma-emitting tracers have satisfactory characteristics for nuclear medicine studies and merit further, more detailed evaluation. PET centres will have the opportunity, and the task, to fulfil the expectations aroused by the encouraging preliminary results. (orig./AJ). With 3 figs

  6. Radiation safety audit of a high volume Nuclear Medicine Department

    International Nuclear Information System (INIS)

    Professional radiation exposure cannot be avoided in nuclear medicine practices. It can only be minimized up to some extent by implementing good work practices. The aim of our study was to audit the professional radiation exposure and exposure rate of radiation worker working in and around Department of nuclear medicine and molecular imaging, Tata Memorial Hospital. We calculated the total number of nuclear medicine and positron emission tomography/computed tomography (PET/CT) procedures performed in our department and the radiation exposure to the radiation professionals from year 2009 to 2012. We performed an average of 6478 PET/CT scans and 3856 nuclear medicine scans/year from January 2009 to December 2012. The average annual whole body radiation exposure to nuclear medicine physician, technologist and nursing staff are 1.74 mSv, 2.93 mSv and 4.03 mSv respectively. Efficient management and deployment of personnel is of utmost importance to optimize radiation exposure in a high volume nuclear medicine setup in order to work without anxiety of high radiation exposure

  7. History and Perspectives of Nuclear Medicine in Bangladesh

    Directory of Open Access Journals (Sweden)

    Raihan Hussain

    2016-01-01

    Full Text Available Bangladesh is one of the smaller states in Asia. But it has a long and rich history of nuclear medicine for over sixty years. The progress in science and technology is always challenging in a developing country. In 1958, work for the first Nuclear Medicine facility was commenced in Dhaka in a tin-shed known as ‘Radioisotope Centre’ and was officially inaugurated in 1962. Since the late 50s of the last century nuclear medicine in Bangladesh has significantly progressed through the years in its course of development, but still the facilities are inadequate. At present there are 20 nuclear medicine establishments with 3 PET-CTs, 42 gamma camera/SPECTs with 95 physicians, 20 physicists, 10 radiochemists and 150 technologists. The Society of Nuclear Medicine, Bangladesh (SNMB was formed in 1993 and publishing its official journal since 1997. Bangladesh also has close relationships with many international organizations like IAEA, ARCCNM, AOFNMB, ASNM, WFNMB and WARMTH. The history and the present scenario of the status of nuclear medicine in Bangladesh are being described here.

  8. Ninth Argentine congress on biology and nuclear medicine; fourth Southernmost sessions of ALASBIMN (Latin-American Association of Biology and Nuclear Medicine); first Spanish-Argentine congress on nuclear medicine; first Argentine sessions on nuclear cardiology

    International Nuclear Information System (INIS)

    This work deals with all the papers presented at the 9. Argentine congress on biology and nuclear medicine; IV Southernmost sessions of ALASBIMN; I Spanish-Argentine congress on nuclear medicine and I Sessions Argentine sessions on nuclear cardiology held in Buenos Aires, Argentina, from October 14 - 18, 1991

  9. Quality Management Audits in Nuclear Medicine Practices. 2. Ed. Companion CD-ROM

    International Nuclear Information System (INIS)

    Quality management systems are essential and should be maintained with the intent to continuously improve effectiveness and efficiency, enabling nuclear medicine to achieve the expectations of its quality policy, satisfy its customers and improve professionalism. The quality management (QM) audit methodology in nuclear medicine practice, introduced in this publication, is designed to be applied to a variety of economic circumstances. A key outcome is a culture of reviewing all processes of the clinical service for continuous improvement in nuclear medicine practice. Regular quality audits and assessments are vital for modern nuclear medicine services. More importantly, the entire QM and audit process has to be systematic, patient oriented and outcome based. The management of services should also take into account the diversity of nuclear medicine services around the world and multidisciplinary contributions. The latter include clinical, technical, radiopharmaceutical, medical physics and radiation safety procedures. This companion CD-ROM is attached to the printed STI/PUB/1683 and contains the full-text of STI/PUB/1683 as well as checklists in PDF and Excel format and a table with the contents of a standardized audit report

  10. Radiological Justification for and Optimization of Nuclear Medicine Practices in Korea.

    Science.gov (United States)

    Kim, Byung Il

    2016-02-01

    Nuclear medicine is a rapidly growing discipline that employs advanced novel hybrid techniques that provide unique anatomical and functional information, as well as targets for molecular therapy. Concomitantly, there has been an increase in the attention paid to medical radiation exposure. A radiological justification for the practice of nuclear medicine has been implemented mainly through referral guidelines based on research results such as prospective randomized clinical trials. The International Commission on Radiological Protection recommends diagnostic reference levels as a practical mechanism to optimize medical radiation exposure in order to be commensurate with the medical purpose. The Korean Society of Nuclear Medicine has been implementing radiological optimization through a survey of the protocols on how each hospital determines the dose of administration of each radiopharmaceutical. In the case of nuclear medicine, radiation exposure of caregivers and comforters of patients discharged after administration of therapeutic radiopharmaceuticals can occur; therefore, optimization has been implemented through written instructions for patients, based on international recommendations. The development of patient-radiation-dose monitoring software, and a national registry and management system of patient-radiation-dose is needed to implement radiological optimization through diagnostic reference levels. This management system must work in agreement with the "Institute for Quality Management of Nuclear Medicine", and must take into account the medical reality of Korea, such as low medicine fee, in order to implement reasonable radiological justification and optimization. PMID:26908990

  11. Importance of the quality control tests in nuclear medicine

    International Nuclear Information System (INIS)

    Full text: The acceptance of nuclear energy and its application by some part of the population are associated with the benefits brought by those activities and the guarantee that the incorporation of this technology will be strictly done according to the currently security norms. This project aims at presenting the Nuclear Medicine tests of control of quality models to assist the National Commission of Nuclear Energy Program of Regulatory Inspection (CNEN). The main aspects related with the radiological protection are discussed along the project and it is presented models that assist the Nuclear Medicine Service, in the matter of Radioprotection paying attention to the requirements of the Regulatory Inspection of CNEN. The fulfilment of such models shows, clearly, that they are fundamental for the radioprotection safety in the Nuclear Medicine Services. (author)

  12. Literature and medicine: contributions to clinical practice.

    Science.gov (United States)

    Charon, R; Banks, J T; Connelly, J E; Hawkins, A H; Hunter, K M; Jones, A H; Montello, M; Poirer, S

    1995-04-15

    Introduced to U.S. medical schools in 1972, the field of literature and medicine contributes methods and texts that help physicians develop skills in the human dimensions of medical practice. Five broad goals are met by including the study of literature in medical education: 1) Literary accounts of illness can teach physicians concrete and powerful lessons about the lives of sick people; 2) great works of fiction about medicine enable physicians to recognize the power and implications of what they do; 3) through the study of narrative, the physician can better understand patients' stories of sickness and his or her own personal stake in medical practice; 4) literary study contributes to physicians' expertise in narrative ethics; and 5) literary theory offers new perspectives on the work and the genres of medicine. Particular texts and methods have been found to be well suited to the fulfillment of each of these goals. Chosen from the traditional literary canon and from among the works of contemporary and culturally diverse writers, novels, short stories, poetry, and drama can convey both the concrete particularity and the metaphorical richness of the predicaments of sick people and the challenges and rewards offered to their physicians. In more than 20 years of teaching literature to medical students and physicians, practitioners of literature and medicine have clarified its conceptual frameworks and have identified the means by which its studies strengthen the human competencies of doctoring, which are a central feature of the art of medicine. PMID:7887555

  13. Application and Exploration of Big Data Mining in Clinical Medicine

    OpenAIRE

    Yue Zhang; Shu-Li Guo; Li-Na Han; Tie-Ling Li

    2016-01-01

    Objective: To review theories and technologies of big data mining and their application in clinical medicine. Data Sources: Literatures published in English or Chinese regarding theories and technologies of big data mining and the concrete applications of data mining technology in clinical medicine were obtained from PubMed and Chinese Hospital Knowledge Database from 1975 to 2015. Study Selection: Original articles regarding big data mining theory/technology and big data mining′s app...

  14. Hepatitis B vaccination schedules in genitourinary medicine clinics.

    OpenAIRE

    Asboe, D; Rice, P.; Ruiter, A.; Bingham, J S

    1996-01-01

    OBJECTIVES: To compare two vaccination schedules in delivering hepatitis B vaccine to at-risk genitourinary medicine clinic attenders. SETTING: Genitourinary medicine clinic of St Thomas' Hospital, London, UK. METHODS: Two vaccination protocols were compared. Between January 1991 and December 1992, individuals had doses of recombinant hepatitis B vaccine at 0, 1 and 6 months (standard). From January until October 1993 doses of vaccine were administered at 0, 1 and 2 months (accelerated), foll...

  15. Dosimetry and radiological safety of the patient in nuclear medicine procedures

    International Nuclear Information System (INIS)

    Estimation of radiation in clinical diagnostic work is needed for judging the risk associated with the use of specific radio-pharmaceuticals, both for comparison with the possible benefit of the investigation and to help in giving adequate guidance to the patient. Dosimetry and radiological safety of the patient in nuclear medicine procedures are studied

  16. Nuclear medicine imaging of bone infections.

    Science.gov (United States)

    Love, C; Palestro, C J

    2016-07-01

    Osteomyelitis is a broad group of infectious diseases that involve the bone and/or bone marrow. It can arise haematogenously, via extension from a contiguous infection, or by direct inoculation during surgery or trauma. The diagnosis is not always obvious and imaging tests are frequently performed as part of the diagnostic work-up. Commonly performed radionuclide tests include technetium-99m ((99m)Tc)-diphosphonate bone scintigraphy (bone), and gallium-67 ((67)Ga) and in vitro labelled leukocyte (white blood cell; WBC) imaging. Although they are useful, each of these tests has limitations. Bone scintigraphy is sensitive but not specific, especially when underlying osseous abnormalities are present. (67)Ga accumulates in tumour, trauma, and in aseptic inflammation; furthermore, there is typically an interval of 1-3 days between radiopharmaceutical injection of and imaging. Currently, this agent is used primarily for spinal infections. Except for the spine, WBC imaging is the nuclear medicine test of choice for diagnosing complicating osteomyelitis. The in vitro leukocyte labelling process requires skilled personnel, is laborious, and is not always available. Complementary marrow imaging is usually required to maximise accuracy. Not surprisingly, alternative radiopharmaceuticals are continuously being investigated. Radiolabelled anti-granulocyte antibodies and antibody fragments, investigated as in vivo leukocyte labelling agents, have their own limitations and are not widely available. (111)In-biotin is useful for diagnosing spinal infections. Radiolabelled synthetic fragments of ubiquicidin, a naturally occurring human antimicrobial peptide that targets bacteria, have shown promise as infection specific radiopharmaceuticals. 2-[(18)F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography (PET) with or without computed tomography (CT) is very useful in musculoskeletal infection. Sensitivities of more than 95% and specificities ranging from 75-99% have been

  17. Applications of CdTe to nuclear medicine. Final report

    International Nuclear Information System (INIS)

    Uses of cadmium telluride (CdTe) nuclear detectors in medicine are briefly described. They include surgical probes and a system for measuring cerebral blood flow in the intensive care unit. Other uses include nuclear dentistry, x-ray exposure control, cardiology, diabetes, and the testing of new pharmaceuticals

  18. Radiation safety of staff and public in nuclear medicine procedures

    International Nuclear Information System (INIS)

    Use of radio-pharmaceuticals in nuclear medicine results in radiation exposure to the staff and public. This exposure is to be kept as low as reasonably achievable by observing necessary safety precautions in day to day work with radionuclides. This paper discusses the nuclear practices where potential exposure exists and mentions the radiation safety procedures that to be followed. (author)

  19. Nuclear medicine in dentistry revisited: New avenues to explore

    Directory of Open Access Journals (Sweden)

    Vinita Boloor

    2013-01-01

    Full Text Available Nuclear medicine and radioactive tracers have considerable application in dental research, because they provide one of the few practical methods for studying the limited metabolic activities of bones and teeth. The ease with which minute amounts of these radioactive materials may be accurately measured and distinguished from the mass of inert element in the tooth is particularly valuable. They are useful in studying many problems of calcification and mineral exchange. There are also opportunities of their use in investigating fluorosis, caries protection, periodontal disease, micro leakage studies of dental materials, root resorption, nutritional, and endocrine effects, as well as numerous other dental problems. Other usages of nuclear medicine in dentistry are listed below: Age written in teeth by nuclear tests, scintigraphic evaluation of osteoblastic activity, and evaluation of osteoblastic activity around dental implants using bone scintigraphy. Nuclear medicine can be an indicator of "active" alveolar bone loss. Nuclear medicine techniques are used as an adjunct for the diagnosis of oral diseases (benign tumors and carcinomas and temporomandibular joint disease. This review article discusses these indications of nuclear medicine.

  20. Economic issue in pediatric nuclear medicine: Cortical scanning of acute pyelonephritis

    International Nuclear Information System (INIS)

    Pediatric nuclear medicine must be innovative in finding ways of competing with other pediatric imagining subspecialties for the health care dollars. Newer radiopharmaceuticals and imagining methods that are time-effective in answering clinical problems and cost-effective in attracting the health care providers are ways of accomplishing this difficult task. Renal cortical scanning for the diagnosis of acute pyelonephritis is presented as an example of an existing nuclear medicine study that is accurate and cost-effective, but has not yet taken a major place in the imaging 'armamentarium'. In this discussion, the cortical scan is endorsed as the primary imaging tool for children presenting with acute urinary infection

  1. Application of medical psychology in the reception of nuclear medicine department

    International Nuclear Information System (INIS)

    Reception of nuclear medicine department is often ignored. In fact, it is an important part of clinical work. If the patient's psychological status is understood, and the psychological knowledge is handles and applied in practice, the quality of work can be improved. The personnel in nuclear medicine should recognize the significance of humanity in medical practice and acquire the communication skill between doctors and patients. They should also understand the four aspects of psychological need of patients: The need of being understood and respected; the need of being greeted, accepted and a sense of belonging; the need of being informed; the need of feeling safe and rehabilitated

  2. Extract from IAEA's Resources Manual in Nuclear Medicine - Part 2. - Human Resources Development

    International Nuclear Information System (INIS)

    The Nuclear Medicine Section of the International Atomic Energy Agency is now engaged in finalizing a reference manual in nuclear medicine, entitled, 'Resources Manual in Nuclear Medicine'. Several renowned professionals from all over the world, from virtually all fields of nuclear medicine have contributed to this manual. The World Journal of Nuclear Medicine will publish a series of extracts from this manual as previews. This is the second extract from the Resources Manual, Part-2 of the chapter on Human Resources Development. (author)

  3. Extracts from IAEA's Resources Manual in Nuclear Medicine - Part 1 - Human Resource Development

    International Nuclear Information System (INIS)

    The Nuclear Medicine Section of the International Atomic Energy Agency is now engaged in finalizing a reference manual in nuclear medicine, entitled, 'Resources Manual in Nuclear Medicine'. Several renowned professionals from all over the world, from virtually all fields of nuclear medicine have contributed to this manual. The World Journal of Nuclear Medicine will publish a series of extracts from this manual as previews. This is the first extract from the Resources Manual, Part-1 of the chapter on Human Resources Development. (author)

  4. Misconceptions and misunderstandings about nuclear medicine; are we selling our wares properly (abstract)

    International Nuclear Information System (INIS)

    Nuclear Medicine is a powerful but unfamiliar if not esoteric modality. This is not taught in medical schools with the result that clinicians usually learn to use this 'on the job' and by 'word of mouth'. It is thus not surprising that many patients referred for a Nuclear medicine procedure have less than optimum indications for the test. This ties up Nuclear Medicine resources, causes a financial loss to the patient and the State (Nuclear Medicine is still heavily State subsidized) and delivers a radiation burden to a patient who might not benefit from it. This study was done to assess physicians perception of the usefulness of Nuclear Medicine procedures in specific medical conditions. 34 physicians, from both Medical (24) and surgical (10) specialists agreed to participate in this study. There were 6 consultants, 21 post-graduate residents and 7 graduate house officers. They were asked to grade from 1 to 5 (useless to most useful and essential) 46 conditions and 7 types of Nuclear Medicine procedures. The 4398 individual results were averaged to form 138 group results. These were then compared with our own impression of the usefulness of the procedures on the same scale. Our impression for each condition was then standardized to an arbitrary value of 5 and all responses were then corrected for this value. These results show that there was relative agreement (Our score of 5, physician score between 4-6 (-+ 20%) between our and the physicians understanding of the usefulness of these procedures in only 9 cases out of 46 (19%); with a more liberal criterion of - + 25% (score of 3.75-6.25) there was agreement in 16 out of 46 cases (35%). The purpose of the study was not to judge physicians knowledge but to highlight the lack of communication that exists between the Nuclear Medicine community in Multan and the clinical staff. It is our feeling that the situation in the rest of the country might be similar. If that is so, there is a tremendous opportunity of saving

  5. Misconceptions and misunderstandings about nuclear medicine: are we selling our wares properly? (abstract)

    International Nuclear Information System (INIS)

    Nuclear medicine is powerful but unfamiliar if not esoteric modality. This is not taught in medical schools with the result that clinicians usually learn to use this ''on the job word of mouth''. It is thus not surprising that many patients referred for a Nuclear Medicine procedure have less than optimum indication for the test. This ties up Nuclear Medicine resources, causes a financial loss to the patient and the State (Nuclear Medicine is still heavily State subsidized) and delivers a radiation burden to a patient who might not benefit from it. This study was done to assess physicians perception of the usefulness of nuclear Medicine procedures in specific medical conditions. 34 physicians, from both Medical (24) and surgical (10) specialists agreed to participate in this study. There were 6 consultants, 21 post-graduate residents and 7 graduates house officer. They were asked to grade from 1 to 5 (useless to most useful and essential) 46 conditions and 7 types of Nuclear Medicine procedures. The 4398 individual results were average to form 138 group results. These were than compared to our own impression of the usefulness of the procedures on the same scale. Out impression for each condition was then standardized to an arbitrary value of 5 and all responses were than corrected for this value. These results show that there was relative agreement (our score of 5, physician score between 4-6 (- +2%) between our and the physicians understanding of the usefulness of these procedures in only 9 cases out of 46 (19%); with a more liberal criterion of -+25% (score of 3.75-6.25) there was agreement in 16 out of 46 cases (35%). The purpose of the study was not to judge physicians knowledge but to highlight the lack of communication that exist between the Nuclear Medicine community in Multan and the clinical staff. It is our feeling that the situation in the rest of the country might be similar. If that is no there is a tremendous opportunity of saving scarce resources and

  6. Quality assurance for radioactive measurement in nuclear medicine

    International Nuclear Information System (INIS)

    interrelated or interacting elements for establishing policies and objectives and enabling the objectives to be achieved in a safe and efficient way. The management system is designed to fulfil requirements that integrate elements related to safety, health, the environment, security, quality and economics. Safety is the fundamental principle upon which the management system is based. It is also recognized in GS-R-3 that QC and QA are important components of the management system. While QC is a means of applying controls to ensure that the product or service consistently meets specifications, QA is an interdisciplinary management tool that provides a means for ensuring that all work is adequately planned, correctly performed and assessed. A QA programme is designed primarily to ensure the quality of a product for a customer and may be appropriate to control the activities in radioactivity measurement in nuclear medicine. However, it would be more effective if these QA controls were integrated into a single management system. There are numerous processes that review and assess financial and technical performance, the achievement of goals and the effectiveness of an organization's processes. It is necessary to integrate the results of all assessment activities to focus decision making on the needs of the business strategy. It is important to understand how assessments enable managers to achieve higher standards of performance. The principles in this publication are based on those described in IAEA Safety Standards Series No. GS-R-3 and in the General Requirements for the Competence of Testing and Calibration Laboratories (ISO/IEC 17025:1999), which set requirements that testing and calibration laboratories must meet to demonstrate that they have a management system in place and are technically competent. The present report provides information specific to implementing these standards at both the end user (clinic) and the secondary standards radioactivity laboratory levels. If

  7. Clinical Holistic Medicine: When Biomedicine is Inadequate

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2004-01-01

    Full Text Available The modern physician is using pharmaceuticals as his prime tool. Unfortunately, this tool is much less efficient than you might expect from the biochemical theory. The belief in drugs as the solution to the health problems of mankind, overlooking important existing knowledge on quality of life, personal development, and holistic healing seems to be one good reason why approximately every second citizen of our modern society is chronically ill. The biomedical paradigm and the drugs are certainly useful, because in many situations we could not do without the drugs (like antibiotics, but curing infections or diseases in young age is not without consequences, as the way we perceive health and medicine is influenced by such experiences. When we get a more severe disease in midlife, we also believe drugs will make us healthy again. But at this age, the drugs do not work efficiently anymore, because we have turned older and lost much of the biological coherence that made us heal easily when we were younger. Now we need to assume responsibility, take learning, and improve our quality of life. We need a more holistic medicine that can help us back to life by allowing us to access our hidden resources. The modern physician cannot rely solely on drugs, but must also have holistic tools in his medical toolbox. This is the only way we can improve the general health of our populations. Whenever NNT (Number Needed to Treat is 2 or higher, the likelihood of the drug to cure the patient is less than 50%, which is not satisfying to any physician. In this case, he must ethically try something more in order to cure his patients, which is the crossroads where both traditional manual medicine and the tools of a scientific holistic medicine are helpful.

  8. Diagnostic and therapeutic capabilities of modern nuclear medicine

    International Nuclear Information System (INIS)

    Full text: Nuclear medicine activity began to expand in the latter half of 1970 in worldwide. In 1980, many countries experienced a rapid increase in the number of medical facilities with nuclear medicine modalities. Nuclear imagining procedures serve as effective diagnostic tools due to their unique ability to provide information that is function-specific and to gather detailed information from radiological exams and other treatment methods. In-vivo studies using SPECT and PET modalities have shown a trend of significant increase throughout the past two decades. Looking at the nuclear neurologic application, there is a rapid increase in last decade. Brain perfusion SPECT and brain PET were making it the most commonly and the most widely performed nuclear neuroimaging study. Since 1990s, conventional nuclear cardiology studies (MUGA and single pass study) declined in number. But myocardial SPECT only increased dramatically using thallium and Tc-99m-MIBI. MIBG imaging plays a prominent role in diagnosing pheochromocytomas/paragangliomas (including nonfunctional paragangliomas) and neuroblastomas. It may be regarded as a first-choice imaging technique, as it presents a wide range of clinical advantages in both the diagnosis and follow-up of these tumors. Regarding to the radioisotope treatment, only radioiodine therapy was used more clinically. But recently, some new treatment is being tried, for example Ho-166 and rhenium-188. I-131 MIBG therapy is an effective treatment for several neural crest tumors, with can be delivered safely, even in children, provided that the bone marrow is free of tumor cells. I-131 MIBG therapy is probably the best palliative treatment for patients with advanced disease, as the invasiveness and toxicity of this therapy compare favorably with that of chemotherapy, immunotherapy and external beam radiotherapy. In general, PET has been primarily used to evaluate ischemic heart disease and to perform diagnostic imaging of malignant tumor

  9. Comparative analysis of dosimetry parameters for nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Toohey, R.E.; Stabin, M.G. [Oak Ridge Inst. for Science and Education, TN (United States)

    1999-01-01

    For years many have employed the concept of ``total-body dose`` or ``whole-body dose,`` i.e., the total energy deposited in the body divided by the mass of the body, when evaluating the risks of different nuclear medicine procedures. The effective dose equivalent (H{sub E}), first described in ICRP Publication 26, has been accepted by some as a better quantity to use in evaluating the total risk of a procedure, but its use has been criticized by others primarily because the tissue weighting factors were intended for use in the radiation worker, rather than the nuclear medicine patient population. Nevertheless, in ICRP Publication 52, the ICRP has suggested that the H{sub E} may be used in nuclear medicine. The ICRP also has published a compendium of dose estimates, including H{sub E} values, for various nuclear medicine procedures at various ages in ICRP Publication 53. The effective dose (E) of ICRP Publication 60 is perhaps more suitable for use in nuclear medicine, with tissue weighting factors based on the entire population. Other comparisons of H{sub E} and E have been published. The authors have used the program MIRDOSE 3.1 to compute total-body dose, H{sub E}, and E for 62 radiopharmaceutical procedures, based on the best current biokinetic data available.

  10. Nuclear medicine procedures in the postgenomic era

    International Nuclear Information System (INIS)

    Assessment of gene function following the completion of human genome sequencing may be done using radionuclide imaging procedures. These procedures are needed for the evaluation of genetically manipulated animals or newly designed biomolecules which requires a thorough understanding of physiology, biochemistry and pharmacology. The experimental approaches will involve many new technologies including in vivo imaging with SPECT and PET. Nuclear medicine procedures may be applied for the determination of gene function and regulation using established and new tracers or using in vivo reporter genes such as genes encoding enzymes, receptors, antigens or transporters. Visualization of in vivo reporter gene expression can be done using radiolabelled substrates, antibodies or ligands. Combinations of specific promoters and in vivo reporter genes may deliver information about the regulation of the corresponding genes. Furthermore, protein-protein interactions and activation of signal transduction pathways may be visualized non-invasively. The role of radiolabelled antisense molecules for the analysis of mRNA content has to be investigated. However, possible applications are therapeutic intervention using triplex oligonucleotides with therapeutic isotopes which can be brought near to specific DNA sequences to induce DNA strand breaks at selected loci. Imaging of labelled siRNA's makes sense if these are used for therapeutic purposes in order to assess the delivery of these new drugs to their target tissue. In gene therapy based on the transfer and expression of suicide genes, usually gene coding for the non-mammalian enzymes, the Herpes Simplex virus thymidine kinase (HSVtk) or the yeast and bacterial cytosine deaminase (CD), have been used. After infection of the tumour with the recombinant virus, a non-toxic prodrug is applied systemically, which is subsequently converted to a toxic metabolite by the recombinant gene product. Employing a radiolabelled prodrug and

  11. Radioactive isotopes in clinical medicine and research. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The review on the International Symposium on radioactive isotopes in clinical medicine and research in Bad Hofgastein, Austria, 9-12 January 2008, contains 42 papers and 29 poster contributions on the following topics: radiopharmaceutical sciences; radiopharmaceutical sciences in oncology and cardiology; therapy; endocrinology; molecular imaging; clinical PET; physics: image processing; instrumentation, neurology, psychiatry.

  12. 'QUANUM' - IAEA guidelines for comprehensive self appraisal of nuclear medicine practices

    International Nuclear Information System (INIS)

    The rapid development of nuclear medicine services, sophisticated equipment and radiopharmaceuticals has resulted in an enormous increase in costs and in the need to maintain quality. Quality management (QM) is fundamental for a safe and efficient practice of medicine. Although the focus has been on quantity and level of services in most developing countries, ample evidence suggests that quality of care must be central to any service. This does not only include quality control (QC) and standards of practice, but it is increasingly recognized that a sustainable holistic approach is vital. Guidelines in Nuclear Medicine have been, and continue to be developed by a number of organizations throughout the world. On the international level the IAEA is keen to assist in coordinating the development of such guidelines, but recognizes the need for national guidelines whenever possible. National regulations on the administration of radioactive substances, differences in clinical practice and service delivery, etc. are understandably more meaningful locally. The IAEA guidelines resulted from a consultants meeting that was organized by the IAEA in Vienna in January 2006 to: assess current and future considerations for establishing guidelines for a comprehensive audit of nuclear medicine practices; identify subtle national, regional and international variations in quality systems; create a self appraisal document to serve as a tool for quality improvement by drawing attention to any defaults that might be corrected ahead of any external peer review process; establish guidelines for an external peer review and any follow-up mechanisms; advise the IAEA on required systems for maintaining such a programme. Following a review and discussion of the audit process in different regions of the world, it was concluded that, in general, quality systems are central to safe, efficacious and effective delivery of any service. Clinical audit of nuclear medicine services is likewise important

  13. Capacity for Clinical Research on Herbal Medicines in Africa

    OpenAIRE

    Willcox, Merlin; Siegfried, Nandi; Johnson, Quinton

    2012-01-01

    An electronic survey was used to assess the training needs of clinical and public health researchers who have been involved, and/or plan to become involved, in clinical trials of herbal medicines in Africa. Over 90 researchers were contacted through pre-existing networks, of whom 58 (64%) responded, from 35 institutions in 14 African countries. Over half (57%) had already been involved in a clinical trial of an herbal medicine, and gave information about a total of 23 trials that have already...

  14. [Diabetes and clinical laboratory tests: team medicine].

    Science.gov (United States)

    Matsui, Kiyoko

    2011-11-01

    The presentation at this symposium is from the following two perspectives: 1. Indispensability of team medicine for diabetes treatment: Once diabetes has been diagnosed, long-term treatment is essential. Diabetes is often due to a combination of unhealthy lifestyle factors, and treatment therefore requires patients to improve their lifestyles, a certain amount of stoicism also being needed. Patients also have to overcome events in their lives while suffering from diabetes, at the same time as controlling the diabetes, and such events cause stress for the patients, affecting them both psychologically and in terms of lifestyle, so patients' blood sugar levels are disturbed by interactions between stress and lifestyle factors. Medical personnel monitor the progression of numerous diabetic patients, and take different approaches to treatment on the basis of their experience and specialist knowledge. From various perspectives, maintenance of patients' will to continue with treatment is an important aspect of "team medicine". Enabling patients to be treated while feeling themselves to be supported by the treatment team is important, and is linked to empowerment of patients, which is the ultimate objective of the treatment guidelines. 2. Importance of team medicine, illustrated by diabetic nephropathy: If diabetic nephropathy progresses to Stage II or further, deterioration of the patient's condition is unavoidable. Medical personnel often think that the patients also will be concerned about the nephropathy, and will therefore not forget about having been told they have nephropathy. However, it has been found that, when subjective symptoms are absent, patients often do not fully understand the explanation, and forget about the nephropathy. It is therefore essential for medical personnel to appreciate that the risk of nephropathic progression is increased if patients do not remember about having nephropathy. PMID:22352019

  15. Highlights of the Annual Congress of the European Association of Nuclear Medicine, Istanbul, 2005: the incremental value of nuclear medicine for patient management and care

    International Nuclear Information System (INIS)

    The 2005 Annual Congress of the European Association of Nuclear Medicine (EANM) took place in Istanbul on October 15-19, under the chairmanship of Professor Hatice Durak. The programme was of excellent quality and represented a further step towards the achievement of a standardized EANM congress structure. A large industrial exhibition demonstrated the latest technological innovations and developments within the field. The congress was a great success: there were more than 4,000 participants, and 1,670 abstracts were received. Of these, 1,399 were accepted for oral or poster presentations, with a rejection rate of 16.2%. The original investigations presented were related to different areas of nuclear medicine, and addressed particularly advances in instrumentation and data processing, progress in radiochemistry and pharmacy, novel diagnostics and therapeutics, and new insights in well-established areas of clinical application, such as oncology, cardiology, neurology, psychiatry, endocrinology, paediatrics, nephrology, and infection and inflammation. It is noteworthy that a number of studies presented at this congress focussed on the quantitative interpretation of the imaging data and on pragmatic endpoints, such as adverse outcomes, and identified when nuclear medicine procedures achieved clinical effectiveness for patient care and management. These and many other studies presented at the congress demonstrate once more the crucial role that nuclear medicine has to play in contemporary medicine. This highlights lecture is only a brief summary of the large amount of data presented and discussed, which can be found in much greater detail in the congress proceedings book, published as volume 32, supplement 1 of the Eur J Nucl Med Mol Imaging in September 2005. (orig.)

  16. Application and Exploration of Big Data Mining in Clinical Medicine

    Institute of Scientific and Technical Information of China (English)

    Yue Zhang; Shu-Li Guo; Li-Na Han; Tie-Ling Li

    2016-01-01

    Objective:To review theories and technologies of big data mining and their application in clinical medicine.Data Sources:Literatures published in English or Chinese regarding theories and technologies of big data mining and the concrete applications of data mining technology in clinical medicine were obtained from PubMed and Chinese Hospital Knowledge Database from 1975 to 2015.Study Selection:Original articles regarding big data mining theory/technology and big data mining's application in the medical field were selected.Results:This review characterized the basic theories and technologies of big data mining including fuzzy theory,rough set theory,cloud theory,Dempster-Shafer theory,artificial neural network,genetic algorithm,inductive learning theory,Bayesian network,decision tree,pattern recognition,high-performance computing,and statistical analysis.The application of big data mining in clinical medicine was analyzed in the fields of disease risk assessment,clinical decision support,prediction of disease development,guidance of rational use of drugs,medical management,and evidence-based medicine.Conclusion:Big data mining has the potential to play an important role in clinical medicine.

  17. Training requirements for chemists in radiotracer development for nuclear medicine

    International Nuclear Information System (INIS)

    This panel was organized to address the current and anticipated future shortage of chemists with advanced training to fill positions in the nuclear medicine field. Although hard data and statistics are difficult to acquire, we will attempt to highlight the impact of chemistry on nuclear medicine and to describe the growth of the field which has led to an increasing need for chemists resulting in the current manpower shortage. We also will make recommendations for attracting Ph.D. chemists to careers in nuclear medicine research and possible mechanisms for postgraduate training. Solving this problem and establishing a long term committment and mechanism for advanced training is critically important to meet the current needs of the profession and to assure future growth and innovation. 3 tabs

  18. Imaging technologies for nuclear medicine offering superior functional diagnosis

    International Nuclear Information System (INIS)

    The nuclear medicine examination is a diagnostic procedure in which organ functions, such as metabolism, blood flow, and neurotransmission, are visualized utilizing radioisotope (RI) tracers. It is a type of molecular imaging, in which RI tracers reflect biological functions on a molecular level. To obtain images with high diagnostic accuracy, Toshiba Medical Systems Corporation has developed the following sophisticated technologies for nuclear medicine: a radiation measurement technology with a high time resolution of several hundred picoseconds, a quantification method that can compensate for Compton scattering and photoelectric effects, and an image reconstruction technology. We are supplying proprietary nuclear medicine systems incorporating these technologies with the objectives of decreasing the patient burden and contributing to hospital management efficiency through reduction of radiation doses and shortening of examination times. (author)

  19. Report: dosimetry of diagnostic exams in nuclear medicine

    International Nuclear Information System (INIS)

    A compilation about dosimetry of diagnosis explorations in nuclear medicine is presented in this issue. Dosimetry tables of the different radiopharmaceuticals used in nuclear medicine give indications on absorbed and efficient doses according the patients age from one year to adult age. The doses received by a fetus during a lung scintigraphy realized for the pregnant woman susceptible to suffer of pulmonary emboli is presented. A table of efficient doses for the infants until the age of six months for the principal scintigraphy explorations realized in nuclear medicine are given. A chapter of theoretical headlines is devoted to dosimetry and the calculations methods of absorbed and efficient doses in function of patients age. A short chapter concerns the recommendations to explore nursing mothers by scintigraphy. A last chapter treats the efficient doses received during explorations using ionizing radiations in radiology and their place in annual natural irradiation scale. (N.C.)

  20. Study of metrologic characteristics in activimeters used in Nuclear Medicine Centers in Colombia; Estudio de caracteristicas metrologicas en activimetros utilizados en centros de Medicina Nuclear de Colombia

    Energy Technology Data Exchange (ETDEWEB)

    Davila, Hernan Olaya; Flores, Guillermo, E-mail: holayadavila@gmail.com [Instituto Colombiano de Geologia y Mineria (INGEOMINAS), Bogota, D.C. (Colombia). Laboratorio de Metrologia de las Radiaciones del Servicio Geologico Colombiano; Cantillo, Juliana I.P., E-mail: julianacantillo5@gmail.com [Universidad Pedagogica y Tecnologica de Colombia, Boyaca (Colombia)

    2013-07-01

    In our country currently there is a legislation that regulated de Nuclear Medicine practice, that establish the criteria about quality assurance in Nuclear Medicine and the justification to imparted to medical exposures. In this work includes some tests to the clinical approval in this type of instruments before to be used. The type of tests are linearity, geometric dependence and the energetic response and moreover to evaluate the total uncertainty during the work the physician using this equipment with radioactive sources. (author)