WorldWideScience

Sample records for clin dev prgms

  1. Haiti DevResults

    Data.gov (United States)

    US Agency for International Development — DevResults is a web-based portfolio management system that tracks program data for the Haiti Mission that was awarded in April of 2013. (The Mozambique and/or...

  2. 玩转DevOps

    Institute of Scientific and Technical Information of China (English)

    韩拓

    2013-01-01

    伴随着互联网时代的真正到来和云计算市场的兴起,DevOps这个词进入了我们的视野。我们可以认为DevOps是一组方法论的统称,它扩大了开发和运维的外延,促进开发、运维、质量保障、运营等各部门的协调与整合,定义了简明、自动化的流程,使我们可以承担更快的变更、更小的风险,

  3. Using Activity Metrics for DEVS Simulation Profiling

    Directory of Open Access Journals (Sweden)

    Muzy A.

    2014-01-01

    Full Text Available Activity metrics can be used to profile DEVS models before and during the simulation. It is critical to get good activity metrics of models before and during their simulation. Having a means to compute a-priori activity of components (analytic activity may be worth when simulating a model (or parts of it for the first time. After, during the simulation, analytic activity can be corrected using dynamic one. In this paper, we introduce McCabe cyclomatic complexity metric (MCA to compute analytic activity. Both static and simulation activity metrics have been implemented through a plug-in of the DEVSimPy (DEVS Simulator in Python language environment and applied to DEVS models.

  4. Management Challenges for DevOps Adoption within UK SMEs

    OpenAIRE

    Jones, Stephen; Noppen, Joost; Lettice, Fiona

    2016-01-01

    The DevOps phenomenon is gathering pace as more UK organisations seek to leverage the benefits it can potentially bring to software engineering functions. However substantial organisational change is inherent to adopting DevOps, especially where there are prior and established methods. As part of a wider piece of doctoral research investigating the management challenges of DevOps adoption, we present early findings of a six month qualitative diary study following the adoption of DevOps within...

  5. 赢在 DevOps

    Institute of Scientific and Technical Information of China (English)

    薛帆

    2015-01-01

    在云计算、大数据等技术颠覆性趋势继续在应用经济下发挥作用的同时,DevOps也已经稳健地在业务思维方式中占有一席之地,2015年对于很多企业来说是DevOps之路的第一步,那么,各大企业应如何更好地迎接这关键性的时刻呢?为此,本刊记者有幸采访到了CA Technologies亚太及日本地区应用交付副总裁Ashok Vasan先生。

  6. Software Development with DevOps

    OpenAIRE

    Kristinsson, Rögnvaldur

    2015-01-01

    The goal of the study was to introduce DevOps in software development, its methods and approaches to software development. I was introduced to the subject by one of my teach-ers, which let me into further studies and researched on the subject and finally choosing it for the study. The subject was completely new to me when I started the study which I found inspirational as I was learning a new and an interesting subject on a daily basis dur-ing the process of writing the study. The materia...

  7. Dev konka bülloza piyoseli

    Directory of Open Access Journals (Sweden)

    Cüneyt Kucur

    2014-06-01

    Full Text Available Konka bülloza,havalanmış (pnömatize veya içinde bir havalı hücre bulunan orta konka için kullanılan bir terimdir. Genellikle asemptomatik olmakla birlikte pnömatizasyonun büyüklüğüne ve nazal septumla olan ilişkisine göre burun tıkanıklığı semptomları verebilir ve ostiomeatal komplekse bası oluşturmakta ise tikanmasina neden olarak sinüzite yol açabilir. Piyosele dönüşmesi nadirdir. Dev konka bülloza endoskopİk muayenede orta konkanin genişlemiş bir bölümü olarak görülür. Konka bülloza kesin tanısı paranazal sinus bilgisayarlı tomografisi (BT ile koyulur. Tedavisinde endoskopik olarak orta konkanın lateral parsiyel rezeksiyonu yeterli ve minimal invazif bir yöntemdir. Bu yazıda sağ nazal pasajı tamamen tıkayan ve nazal vestibüle kadar uzanım gösteren ve aynı tarafta sinüzite yol açan tek taraflı dev konka bülloza piyoseli olgusu sunulmuştur.

  8. 破解DevOps的五大迷思

    Institute of Scientific and Technical Information of China (English)

    Sumal Karunanayake

    2014-01-01

    DevOps集开发、测试、部署和运营为一体,并迅速成为加速应用交付的典型技术。如今,业务成功更加依赖于高质量软件服务,因此DevOps的影响也日益显著。同其他新技术一样,DevOps的出现也激起了许多讨论。在深入理解DevOps之前。

  9. The GenDev Curriculum Development Workshop.

    Science.gov (United States)

    D'cunha, J

    1997-01-01

    This article describes the second Curriculum Development Workshop held in May 1997 at the Asian Institute of Technology (AIT) in Bangkok, Thailand. The workshop aimed to review critically and restructure the Gender and Development Studies (GenDev) curriculum and to assess AIT's role in training gender experts for the region. Participants included 22 people from 16 countries in Asia, Europe, and the US who were teaching graduate students about gender issues and who were activists with nongovernmental organizations working on gender issues. It was determined that the following were required courses: Culture, Knowledge and Gender Relations; Gender, Technology, and Development; Principles of Gender Research and Methodology in Science and Technology; and Gender Analysis and Field Methods. Other suggested core courses included: Gender and Natural Resource Management; Enterprise Management, Technology, and Gender; Gender and Agrarian Reform; Urbanization: A Gender Perspective; Gender-Responsive Development Planning; and Gender and Economic Change: Past and Present Concerns. Participants distinguished between GenDev courses offered to anyone attending AIT and training courses designed to produce gender experts in the region. The aim of training courses for AIT graduate students was to sensitize potential managers, technologists, and others on gender issues and to create awareness of the importance of including gender perspectives within decision-making, policy formation, and implementation. Training courses to produce gender experts should be directed to those with a prior background in gender studies and include gender analysis in field methods. Participants agreed that there should be an independent and autonomous field of gender and development studies. Participants made six recommendations for such a field of study. PMID:12179927

  10. Embracing Agile methodology during DevOps Developer Internship Program

    OpenAIRE

    Patwardhan, Amol; Kidd, Jon; Urena, Tiffany; Rajgopalan, Aishwarya

    2016-01-01

    The DevOps team adopted agile methodologies during the summer internship program as an initiative to move away from waterfall. The DevOps team implemented the Scrum software development strategy to create an internal data dictionary web application. This article reports on the transition process and lessons learned from the pilot program.

  11. Service Provider DevOps network capabilities and tools

    OpenAIRE

    Steinert, Rebecca; John, Wolfgang; Sköldström, Pontus; Pechenot, Bertrand; Gulyás, András; Pelle, István; Lévai, Tamás; Németh, Felicián; Kim, Juhoon; Meirosu, Catalin; Cai, Xuejun; Fu, Chunyan; Pentikousis, Kostas; Sharma, Sachin; Papafili, Ioanna

    2015-01-01

    This report provides an understanding of how the UNIFY Service Provider (SP)-DevOps concept can be applied and integrated with a combined cloud and transport network NFV architecture. Specifically, the report contains technical descriptions of a set of novel SP-DevOps tools and support functions that facilitate observability, troubleshooting, verification, and VNF development processes. The tools and support functions are described in detail together with their architectural mapping, giving a...

  12. DevOps:推倒隔阂之墙

    Institute of Scientific and Technical Information of China (English)

    张贝贝

    2013-01-01

    DevOps是一个融合词,即把开发(Develop)和运维(Operation)合在一起,表面上看,这个词合起来很容易,但实际操作的过程并不容易。因为在开发和运维中间始终有堵墙,DevOps要做的就是将其推倒。

  13. DevS/DosS sensor is bifunctional and its phosphatase activity precludes aerobic DevR/DosR regulon expression in Mycobacterium tuberculosis.

    Science.gov (United States)

    Kaur, Kohinoor; Kumari, Priyanka; Sharma, Saurabh; Sehgal, Snigdha; Tyagi, Jaya Sivaswami

    2016-08-01

    Two-component systems, comprising histidine kinases and response regulators, empower bacteria to sense and adapt to diverse environmental stresses. Some histidine kinases are bifunctional; their phosphorylation (kinase) and dephosphorylation (phosphatase) activities toward their cognate response regulators permit the rapid reversal of genetic responses to an environmental stimulus. DevR-DevS/DosR-DosS is one of the best-characterized two-component systems of Mycobacterium tuberculosis. The kinase function of DevS is activated by gaseous stress signals, including hypoxia, resulting in the induction of ~ 48-genes DevR dormancy regulon. Regulon expression is tightly controlled and lack of expression in aerobic Mtb cultures is ascribed to the absence of phosphorylated DevR. Here we show that DevS is a bifunctional sensor and possesses a robust phosphatase activity toward DevR. We used site-specific mutagenesis to generate substitutions in conserved residues in the dimerization and histidine phosphotransfer domain of DevS and determined their role in kinase/phosphatase functions. In vitro and in vivo experiments, including a novel in vivo phosphatase assay, collectively establish that these conserved residues are critical for regulating kinase/phosphatase functions. Our findings establish DevS phosphatase function as an effective control mechanism to block aerobic expression of the DevR dormancy regulon. Asp-396 is essential for both kinase and phosphatase functions, whereas Gln-400 is critical for phosphatase function. The positive and negative functions perform opposing roles in DevS: the kinase function triggers regulon induction under hypoxia, whereas its phosphatase function prevents expression under aerobic conditions. A finely tuned balance in these opposing activities calibrates the dormancy regulon response output. PMID:27327040

  14. An approach for activity-based DEVS model specification

    DEFF Research Database (Denmark)

    Alshareef, Abdurrahman; Sarjoughian, Hessam S.; Zarrin, Bahram

    2016-01-01

    activity-based behavior modeling of parallel DEVS atomic models. We consider UML activities and actions as fundamental units of behavior modeling, especially in the presence of recent advances in the UML 2.5 specifications. We describe in detail how to approach activity modeling with a set of elemental...

  15. Your data is your dogfood: DevOps in the astronomical observatory

    OpenAIRE

    Economou, Frossie; Hoblitt, Joshua C.; Norris, Pat

    2014-01-01

    DevOps is the contemporary term for a software development culture that purposefully blurs distinction between software development and IT operations by treating "infrastructure as code." DevOps teams typically implement practices summarised by the colloquial directive to "eat your own dogfood;" meaning that software tools developed by a team should be used internally rather thrown over the fence to operations or users. We present a brief overview of how DevOps techniques bring proven softwar...

  16. DevOps不是一个传说!

    Institute of Scientific and Technical Information of China (English)

    薛帆

    2015-01-01

    CA Technologies于近日发布了CA DevOps组合的升级产品——敏捷运维(Agile Operations)解决方案,该方案为组织快速部署新应用、监控动态环境、持续优化应用质量提供所需的速度和规模,从而确保卓越的客户体验。那么,此次发布的敏捷运维解决方案都包含了哪些方面的内容?该解决方案最大的功能特性在哪里?为此,记者对CA Technologies中国区高级架构师王励杰先生进行了专访。

  17. Your data is your dogfood: DevOps in the astronomical observatory

    CERN Document Server

    Economou, Frossie; Norris, Pat

    2014-01-01

    DevOps is the contemporary term for a software development culture that purposefully blurs distinction between software development and IT operations by treating "infrastructure as code." DevOps teams typically implement practices summarised by the colloquial directive to "eat your own dogfood;" meaning that software tools developed by a team should be used internally rather thrown over the fence to operations or users. We present a brief overview of how DevOps techniques bring proven software engineering practices to IT operations. We then discuss the application of these practices to astronomical observatories.

  18. CoreDevRec:Automatic Core Member Recommendation for Contribution Evaluation

    Institute of Scientific and Technical Information of China (English)

    蒋竞; 贺佳欢; 陈学渊

    2015-01-01

    The pull-based software development helps developers make contributions flexibly and effciently. Core members evaluate code changes submitted by contributors, and decide whether to merge these code changes into repositories or not. Ideally, code changes are assigned to core members and evaluated within a short time after their submission. However, in reality, some popular projects receive many pull requests, and core members have di昋culties in choosing pull requests which are to be evaluated. Therefore, there is a growing need for automatic core member recommendation, which improves the evaluation process. In this paper, we investigate pull requests with manual assignment. Results show that 3.2%∼40.6% of pull requests are manually assigned to specific core members. To assist with the manual assignment, we propose CoreDevRec to recommend core members for contribution evaluation in GitHub. CoreDevRec uses support vector machines to analyze different kinds of features, including file paths of modified codes, relationships between contributors and core members, and activeness of core members. We evaluate CoreDevRec on 18 651 pull requests of five popular projects in GitHub. Results show that CoreDevRec achieves accuracy from 72.9% to 93.5% for top 3 recommendation. In comparison with a baseline approach, CoreDevRec improves the accuracy from 18.7% to 81.3% for top 3 recommendation. Moreover, CoreDevRec even has higher accuracy than manual assignment in the project TrinityCore. We believe that CoreDevRec can improve the assignment of pull requests.

  19. Activity Diagrams for DEVS Models: A Case Study Modeling Health Care Behavior

    Energy Technology Data Exchange (ETDEWEB)

    Ozmen, Ozgur [ORNL; Nutaro, James J [ORNL

    2015-01-01

    Discrete Event Systems Specification (DEVS) is a widely used formalism for modeling and simulation of discrete and continuous systems. While DEVS provides a sound mathematical representation of discrete systems, its practical use can suffer when models become complex. Five main functions, which construct the core of atomic modules in DEVS, can realize the behaviors that modelers want to represent. The integration of these functions is handled by the simulation routine, however modelers can implement each function in various ways. Therefore, there is a need for graphical representations of complex models to simplify their implementation and facilitate their reproduction. In this work, we illustrate the use of activity diagrams for this purpose in the context of a health care behavior model, which is developed with an agent-based modeling paradigm.

  20. Hybrid system modeling using the parallel devs formalism and the modelica language

    OpenAIRE

    Sanz Prat, Victorino

    2010-01-01

    El principal objetivo de la presente tesis doctoral es facilitar la descripción, mediante el formalismo DEVS Paralelo y el paradigma del modelado orientado al proceso, y empleando el lenguaje Modelica, de modelos de eventos discretos y de la parte de eventos discretos de modelos DAE-híbridos. El objetivo, por tanto, no sólo es facilitar que pueda emplearse Modelica para describir modelos DEVS Paralelo y orientados al proceso. Además, deben desarrollarse los modelos en Mode...

  1. An Approach for the Implementation of Software Quality Models Adpoting CERTICS and CMMI-DEV

    Directory of Open Access Journals (Sweden)

    GARCIA, F.W.

    2015-12-01

    Full Text Available This paper proposes a mapping between two product quality and software processes models used in the industry, the CERTICS national model and the CMMI-DEV international model. The stages of mapping are presented step by step, as well as the mapping review, which had the cooperation of one specialist in CERTICS and CMMI-DEV models. It aims to correlate the structures of the two models in order to facilitate and reduce the implementation time and costs, and to stimulate the execution of multi-model implementations in software developers companies.

  2. Towards DevOps: Practices and Patterns from the Portuguese Startup Scene

    OpenAIRE

    Carlos Manuel da Costa Martins Teixeira

    2016-01-01

    Formed by combining the word Development with the word Operations, DevOps has been around for sometime. Uses and appearances of the word have been seen in different contexts and with different meanings making it a topic of discussion and discord. For some DevOps is a movement aiming to conciliate Operations and Developers, others believe that its just a set of tools that help automate operations tasks and procedures and others see it as a job or tittle for professionals that combine developer...

  3. Initial Service Provider DevOps concept, capabilities and proposed tools

    OpenAIRE

    John, Wolfgang; Meirosu, Catalin; Sköldström, Pontus; Nemeth, Felician; Gulyas, Andras; Kind, Mario; Sharma, Sachin; Papafili, Ioanna; Agapiou, George; Marchetto, Guido; Sisto, Riccardo; Steinert, Rebecca; Kreuger, Per; Abrahamsson, Henrik; MANZALINI, Antonio

    2015-01-01

    This report presents a first sketch of the Service Provider DevOps concept including four major management processes to support the roles of both service and VNF developers as well as the operator in a more agile manner. The sketch is based on lessons learned from a study of management and operational practices in the industry and recent related work with respect to management of SDN and cloud. Finally, the report identifies requirements for realizing SP-DevOps within an combined cloud and tr...

  4. Towards an automatic model transformation mechanism from UML state machines to DEVS models

    Directory of Open Access Journals (Sweden)

    Ariel González

    2015-08-01

    Full Text Available The development of complex event-driven systems requires studies and analysis prior to deployment with the goal of detecting unwanted behavior. UML is a language widely used by the software engineering community for modeling these systems through state machines, among other mechanisms. Currently, these models do not have appropriate execution and simulation tools to analyze the real behavior of systems. Existing tools do not provide appropriate libraries (sampling from a probability distribution, plotting, etc. both to build and to analyze models. Modeling and simulation for design and prototyping of systems are widely used techniques to predict, investigate and compare the performance of systems. In particular, the Discrete Event System Specification (DEVS formalism separates the modeling and simulation; there are several tools available on the market that run and collect information from DEVS models. This paper proposes a model transformation mechanism from UML state machines to DEVS models in the Model-Driven Development (MDD context, through the declarative QVT Relations language, in order to perform simulations using tools, such as PowerDEVS. A mechanism to validate the transformation is proposed. Moreover, examples of application to analyze the behavior of an automatic banking machine and a control system of an elevator are presented.

  5. NDLS-3000配接GR-DEV-Rmg-Rmn-CAL组合仪%NDLS 3000 Combination Instrument matched with GR-DEV-Rmg-Rmn-CAL

    Institute of Scientific and Technical Information of China (English)

    陈金宏; 刘素洁; 刘国权; 徐涛

    2003-01-01

    首先简单介绍NDLS-3000的特点和华北油田砂泥岩剖面测井项目,分析其他组合测井所存在的问题.再详细说明在NDLS-3000网络双测井系统上配接GR_DEV_Rmg_Rmn_CAL组合仪的方法,包括井下仪器的连接方法和组合测井软件的编制与使用方法.

  6. Teaching DevOps and Cloud Computing using a Cognitive Apprenticeship and Story-Telling Approach

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak

    2016-01-01

    DevOps is a new way of developing software that is challenging from a teaching perspective. In this paper, we outline these challenges and propose teaching methods that focus on skill acquisition and technical practices that focus on performant virtualization to overcome them. We describe central...... elements from our course Cloud Computing and Architecture that has been designed and executed upon these methods and practices and report our experiences and lessons learned....

  7. Structure-function analysis of the ATP-driven glycolipid efflux pump DevBCA reveals complex organization with TolC/HgdD.

    Science.gov (United States)

    Staron, Peter; Forchhammer, Karl; Maldener, Iris

    2014-01-31

    In Gram-negative bacteria, trans-envelope efflux pumps have periplasmic membrane fusion proteins (MFPs) as essential components. MFPs act as mediators between outer membrane factors (OMFs) and inner membrane factors (IMFs). In this study, structure-function relations of the ATP-driven glycolipid efflux pump DevBCA-TolC/HgdD from the cyanobacterium Anabaena sp. PCC 7120 were analyzed. The binding of the MFP DevB to the OMF TolC absolutely required the respective tip-regions. The interaction of DevB with the IMF DevAC mainly involved the β-barrel and the lipoyl domain. Efficient binding to DevAC and TolC, substrate recognition and export activity by DevAC were dependent on stable DevB hexamers. PMID:24361095

  8. Aplicación de herramientas DevOps en entornos de Desarrollo Web

    OpenAIRE

    MUÑOZ MARÍN, SIMÓN

    2015-01-01

    A lo largo del proyecto presentaremos la problemática a las que se enfrentan gran parte de las empresas de desarrollo web, con la gestión de los distintos entornos dónde se codifican y ejecutan sus aplicaciones. Para solucionarlo, introduciremos el movimiento DevOps y cómo herramientas creadas en torno al mismo como VirtualBox, Vagrant y Ansible, nos permiten redefinir la forma de trabajar de estas empresas y aumentar su productividad en el camino. Muñoz Marín, S. (2015). Aplic...

  9. Implementation and Analysis of DEVS Activity-Tracking with DEVSimPy

    Directory of Open Access Journals (Sweden)

    Santucci J.F.

    2013-01-01

    Full Text Available This paper deals with the implementation of Activity-Tracking (AT paradigm in the DEVSimPy environment. DEVSimPy has been developed at the SPE UMR CNRS6134 (University of Corsica in order to facilitate the modeling and the simulation of discrete-event systems described with the DEVS formalism. The AT paradigm is increasingly being used by DEVS modelers for example to improve structural aspects of models (modeling level or to make simulation more efficient using distributed or parallel algorithm (simulation level. Although DEVSimPy can be used as a software providing some features reusable for the implementation of AT paradigm (simulation profiling or step-by-step simulation, the object oriented way used to develop DEVSimPy makes it a powerful tool to implement AT paradigm in a generic manner. DEVSimPy may be viewed as an experimental framework allowing the implementation of new AT techniques while opening up new perspectives in the field of activity modeling and simulation theory.

  10. Aynı Hastada Oluşan Santral ve Periferal Dev Hücreli Granüloma Olgusu

    OpenAIRE

    Sümer, A.Pınar; SÜMER, Mahmut; Telcioğlu, N.Tuba; Çelenk, Peruze; Günhan, Ömer

    2011-01-01

    Dev hücreli granüloma, bazen neoplazmlar gibi agresif davranış gösterse de, nonneoplastik bir lezyon olarak kabul edilmektedir. Santral ve periferal dev hücreli granüloma ile ilgili pek çok çalışma vardır. Bununla birlikte ikisinin birden aynı hastada bulunduğubir olgu henüz rapor edilmemiştir. Sunulan bu olgu raporunda, aynı hastada oluşan santral ve periferal dev hücreli granülomalar iki lezyon arasında bir ilişki olabileceği fikrini verebilir. İleride yapılacak benzer olgu raporları da bu ...

  11. Uso de DevC++® con Delmia Quest® para Optimizar Simulaciones

    Directory of Open Access Journals (Sweden)

    Ricardo Pérez Rodríguez

    2014-01-01

    Full Text Available En este artículo se presentan los elementos básicos e imprescindibles utilizados para lograr comunicación entre cualquier algoritmo de optimización que se programe en el entorno de programación DevC++ ® y que sea utilizado para optimizar modelos de simulación en Delmia Quest ® versión R19 o superiores. El objetivo de este artículo es facilitar el aprendizaje para comunicar ambas plataformas con el fin de sistematizar y automatizar la evaluación de las soluciones desde un punto de vista práctico. El aporte central de este artículo es el desarrollo y validación de un tutorial para demostrar el proceso de intercomunicación entre Delmia Quest ® y DevC++ ® . La idea global se refiere a construir un procedimiento que enlaza las instrucciones del algoritmo de optimización programado en DevC++ ® la cuales son ejecutadas por el lenguaje de simulación Delmia Quest ® , el cual devuelve algún parámetro con la información pertinente de nuevo al algoritmo de optimización. El procedimiento se repite iterativamente de acuerdo a las especificaciones del algoritmo de optimización. Con el presente tutorial, los usuarios podrán iniciar rápidamente la programación de sus propias rutinas de comunicación inclusive en otros lenguajes de programación como Java ® ahorrado recursos en costosos cursos de capacitación. Finalmente, 10 estudiantes de ingeniería probaron la efectividad del documento, al menos 50% de ellos consumieron entre 12 y 17 minutos para terminar exitosamente la programación del tutorial propuesto, donde tradicionalmente como factor barrera se pueden requerir horas e inclusive días ya que no existe bibliografía accesible y clara en el idioma español.

  12. Association between CMMI-DEV 1.2 AND ISO/TS 16949

    Directory of Open Access Journals (Sweden)

    Altamar Urbanetz de Araújo Albanez

    2014-05-01

    Full Text Available The automotive sector is one of the most daring in terms of quality, requiring ISO/TS 16949 certification. Nevertheless, there are companies those lose their certification or develop only some improvements due to a lack of enough maturity to maintain it and gaps in continuous improvement guidelines. Whereas CMMI is one of the diagnostic methods of maturity, the aim of this work is to identify the feasibility of linking the ISO/TS 16949 with the CMMI-DEV 1.2. The method used consists in review PDPs, quality certification and process maturity and then associate these two models. The analysis concludes that a company certified by ISO/TS not necessarily even reaches the maturity level 2 in CMMI. Moreover, while the CMMI model shows those items not covered and demand their development, ISO/TS only encourages "continuous improvement" without a plan or diagnostics for the company operationally achieve it.

  13. Clin Pharmacol Ther

    OpenAIRE

    Seiter, A

    2009-01-01

    "Counterfeit Drugs Kill" is the slogan the World Health Organization (WHO) uses in its anti-counterfeiting campaign. International organizations, governments of developed and developing countries, and the pharmaceutical industry created the IMPACT initiative (International Medical Products Anti-Counterfeiting Taskforce) to take on the thriving illegal industry that makes profits by selling fake drugs. However, before committing resources, policy makers want to assess the burden caused by coun...

  14. Decreased C3 Activation by the devR Gene-Disrupted Mycobacterium tuberculosis Strain in Comparison to the Wild-Type Strain

    Directory of Open Access Journals (Sweden)

    V. Narayan Rao

    2013-01-01

    Full Text Available Activation of the complement component C3 is an important step in the complement cascade, contributing to inflammatory mechanisms. Considerable research on gene-disrupted mycobacterial strains using animal models of tuberculosis infection has reported the roles of some of the mycobacterial genes during tuberculosis infection. The aim of the present study was to assess the pattern of complement activation by the devR gene-disrupted Mycobacterium tuberculosis H37Rv strain and compare with that by its wild-type strain. In vitro complement activation at the level of C3 by the gene-disrupted strain, its complemented strain, and wild-type strain was performed using solid-phase ELISA. It was observed that the ability of devR gene-disrupted M. tuberculosis H37Rv to activate C3 was significantly reduced in comparison to its wild-type strain (P<0.05. In addition, C3 activation by the complemented devR mutant strain was almost similar to that of the wild strain, which indicated that the reduced ability to activate C3 could potentially be due to the deletion of devR gene. These findings indicate that the gene devR probably aids in complement activation and contributes to the inflammatory processes during tuberculosis infection.

  15. Webová aplikace pro vzdálené modelování a simulaci na bázi DEVS

    OpenAIRE

    Gavlík, Pavel

    2013-01-01

    Práce se zabývá návrhem a realizací webové aplikace pro vzdálený přístup k nástroji Small- DEVS, implementaci formalismu DEVS. Komunikace po síti je realizována pomocí RESTful API. Webová aplikace je napsána převážně v programovacím jazyce JavaScript s využitím frameworku AngularJS. Při vývoji webové aplikace byla použita technika Test Driven Development.  This paper deals with the design and implementation of a web application for remote access to SmallDEVS, implementation of D...

  16. AOX determination in industrial waste water according to EN 1485, DEV H14. Experience with high salt freights and interfering organic matter; AOX-Bestimmungen in Industrieabwaessern nach EN 1485, DEV H14 Erfahrungen mit hohen Salzfrachten und organischen Stoerstoffen

    Energy Technology Data Exchange (ETDEWEB)

    Helmreich, B. [Technische Univ. Muenchen, Garching (Germany). Lehrstuhl und Pruefamt fuer Wasserguete- und Abfallwirtschaft

    1999-07-01

    AOX determination in industrial waste water is not always trivial on account of high salt freights or high organic loads. Interfering substances of inorganic or organic nature can cause increases or decreases of readings that often are not plausible or reproducible. In most cases the AOX enrichment step is limiting to quantitative analysis. In the present work, enrichment in two industrial waste waters was critically assessed according to EN 1485 DEV H14. In addition, experience with the enrichment method according to Dr. Lange is reported. For the elimination of high salt freights beside a low organic concentration, cleanup by means of solid-phase extraction is considered. The results suggest that the standardized procedure is not universally applicable to any type of sample. However, appropriate action can minimize flaws of enrichment and, thereby, AOX determination. (orig.) [German] Die AOX-Bestimmung aus Industrieabwaessern ist aufgrund hoher Salzfrachten oder hoher organischer Belastungen nicht immer trivial. Stoerstoffe anorganischer wie auch organischer Art koennen zu Mehr- oder Minderbefunden fuehren, die oft nicht plausibel und reproduzierbar sind. In den meisten Faellen ist der Anreicherungsschritt des AOX fuer die quantitative Analyse limitierend. In der vorliegenden Arbeit wurde die Anreicherung nach den EN 1485 DEV H14 fuer zwei Industrieabwaesser kritisch betrachtet. Zudem werden Erfahrungen mit der Anreicherungsmethode nach Dr. Lange vorgestellt. Zur Entfernung hoher Salzfrachten neben einer geringen organischen Konzentration wurde ein Clean-up mittels Festphasenextraktion betrachtet. Die Ergebnisse legen nahe, dass das genormte Verfahren nicht universell auf jeden Probentyp anwendbar ist. Durch ein gezieltes Vorgehen koennen jedoch Fehler bei der Anreicherung und damit bei der AOX-Bestimmung minimiert werden. (orig.)

  17. 基于HLA的Agent-DEVS协同仿真建模%Collaborative modeling and simulation of Agent-DEVS based on HLA

    Institute of Scientific and Technical Information of China (English)

    曹琦; 何中市; 余磊

    2011-01-01

    In order to extend the DEVS with abilities of intelligent modeling and distributed simulation, a collaborative modeling and simulation method for Agent-DEVS based on HLA was studied. The formal description of Agent-DEVS federate models based on ParalIeI-DEVS was proposed. The models ports in Agent-DEVS were translated into data objects in HLA and the structure of the models was given. The communication mechanism was analyzed. The mapping between knowledge update in Agent-DEVS and attribute update in HLA, and that between models coupling in Agent-DEVS and instances interaction in HLA, were established respectively. Finally, the modeling and simulation application for material supply in emergent disaster was put forward. The results show that the reusability of Agent-DEVS models is enhanced by HLA and the interoperability of the models is enriched by knowledge update mechanism. In addition, the autonomy and independent ability for transaction processing are improved significantly.%为实现DEVS在智能建模与分布仿真能力方面的扩充,研究了基于HLA的Agent-DEVS协同仿真建模方法.以并行DEVS为基础,提出了Agent-DEVS联邦模型的形式化描述;将Agent-DEVS模型端口转换为HLA数据对象,确定了Agent-DEVS联邦模型结构,并分析了通信机制,分别建立了Agent-DEVS的知识更新与HLA的属性更新间的映射,以及Agent-DEVS的模型耦合与HLA的实例交互间的映射;最后结合抢险救灾物资保障的仿真建模进行了应用.结果表明,HLA体系框架增强了Agent-DEVS模型的可重用性;知识更新机制丰富了Agent-DEVS模型的互操作性;同时,Agent-DEVS模型的自治性与独立事务处理能力得到了进一步提高.

  18. IBM将通过DevOps战略助企业实现移动和云计算创新

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    IBM2013技术峰会日前在京举行,众多创新技术和理念在会上发布,其中以Dev019s软件持续交付为核心的移动、云计算的开发创新成为亮点。据了解,IBM本次推出的一系列新软件、培Sling资源,将有助于推动全球及中国企业机构、开发人员及IT专业人士在移动和云计算应用领域的创新,帮助他们更好地创建、测试和交付基于移动和云计算的应用程序。

  19. Activity-based simulation using DEVS:increasing performance by an activity model in parallel DEVS simulation

    Institute of Scientific and Technical Information of China (English)

    Bin CHEN; Lao-bing ZHANG; Xiao-cheng LIU; Hans VANGHELUWE

    2014-01-01

    Improving simulation performance using activity tracking has attracted attention in the modeling field in recent years. The reference to activity has been successfully used to predict and promote the simulation performance. Tracking activity, how-ever, uses only the inherent performance information contained in the models. To extend activity prediction in modeling, we propose the activity enhanced modeling with an activity meta-model at the meta-level. The meta-model provides a set of interfaces to model activity in a specific domain. The activity model transformation in subsequence is devised to deal with the simulation difference due to the heterogeneous activity model. Finally, the resource-aware simulation framework is implemented to integrate the activity models in activity-based simulation. The case study shows the improvement brought on by activity-based simulation using discrete event system specification (DEVS).

  20. Study on Combat Commanding Behavior Modeling Based on DEVS%基于DEVS的作战指挥行为建模研究

    Institute of Scientific and Technical Information of China (English)

    李京; 王子明; 李冬

    2014-01-01

    针对传统计算机兵力生成(computer generated force,CGF)建模所使用的经典人工智能编程语言存在的不足,提出一种基于离散事件系统(discrete event system specification,DEVS)的作战指挥行为建模方法。从DEVS原子模型和耦合的DEVS模型对DEVS做规范介绍,统一、规范描述指挥主体的生理和心理因素如何影响作战指挥行为,建立一种包含评估模块、压力模块和行为模块的作战指挥行为模型。结果表明:该模型能很好地将指挥主体的压力和自身生理状况融入到作战指挥行为中,能较为合理地反映出在紧张对抗环境中指挥主体的实际指挥行为。%Aiming at the shortcoming of typical artificial intelligence programming language for traditional computer generated force (CGF) modeling, put forward a new modeling method of combat commanding behavior based on discrete event system specification (DEVS). From DEVS atomic model and coupling DEVS model, make a standard introduction for DEVS, and also make an unified and standard description about how the physiological and psychological factors of commander make an influence on commanding behavior, establish a commanding behavior model which including evaluation model, pressure model and behavior model. The results show that the model can combine the commander pressure and physiological state with commanding behavior, and it can reflect reasonably the commanding behavior under the circumstance full of nervousness and confrontation.

  1. Analysing inter-relationships among water, governance, human development variables in developing countries: WatSan4Dev database coherency analysis

    Science.gov (United States)

    Dondeynaz, C.; Carmona Moreno, C.; Céspedes Lorente, J. J.

    2012-01-01

    The "Integrated Water Resources Management" principle was formally laid down at the International Conference on Water and Sustainable development in Dublin 1992. One of the main results of this conference is that improving Water and Sanitation Services (WSS), being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation). These sectors influence or are influenced by the access to WSS. The understanding of these interrelations appears as crucial for decision makers in the water sector. In this framework, the Joint Research Centre (JRC) of the European Commission (EC) has developed a new database (WatSan4Dev database) containing 45 indicators (called variables in this paper) from environmental, socio-economic, governance and financial aid flows data in developing countries. This paper describes the development of the WatSan4Dev dataset, the statistical processes needed to improve the data quality; and, finally, the analysis to verify the database coherence is presented. At the light of the first analysis, WatSan4Dev Dataset shows the coherency among the different variables that are confirmed by the direct field experience and/or the scientific literature in the domain. Preliminary analysis of the relationships indicates that the informal urbanisation development is an important factor influencing negatively the percentage of the population having access to WSS. Health, and in particular children health, benefits from the improvement of WSS. Efficient environmental governance is also an important factor for providing improved water supply services. The database would be at the base of posterior analyses to better understand the interrelationships between the different indicators associated in the water sector in developing countries. A data model using the different indicators will be realised on the next phase of this research work.

  2. Analysing inter-relationships among water, governance, human development variables in developing countries: WatSan4Dev database coherency analysis

    Directory of Open Access Journals (Sweden)

    C. Dondeynaz

    2012-01-01

    Full Text Available The "Integrated Water Resources Management" principle was formally laid down at the International Conference on Water and Sustainable development in Dublin 1992. One of the main results of this conference is that improving Water and Sanitation Services (WSS, being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation. These sectors influence or are influenced by the access to WSS. The understanding of these interrelations appears as crucial for decision makers in the water sector. In this framework, the Joint Research Centre (JRC of the European Commission (EC has developed a new database (WatSan4Dev database containing 45 indicators (called variables in this paper from environmental, socio-economic, governance and financial aid flows data in developing countries.

    This paper describes the development of the WatSan4Dev dataset, the statistical processes needed to improve the data quality; and, finally, the analysis to verify the database coherence is presented.

    At the light of the first analysis, WatSan4Dev Dataset shows the coherency among the different variables that are confirmed by the direct field experience and/or the scientific literature in the domain. Preliminary analysis of the relationships indicates that the informal urbanisation development is an important factor influencing negatively the percentage of the population having access to WSS. Health, and in particular children health, benefits from the improvement of WSS. Efficient environmental governance is also an important factor for providing improved water supply services.

    The database would be at the base of posterior analyses to better understand the interrelationships between the different indicators associated in the water sector in developing countries. A data model using the different indicators will be realised

  3. Identificando Hallazgos de Mejora en Pymes de TI Utilizando un Modelo Ontológico para CMMI-DEV v1.3

    Directory of Open Access Journals (Sweden)

    J. Guadalupe Uribe Dévora

    2013-12-01

    Full Text Available Uno de los principales requisitos que deben cumplir las pymes de desarrollo de software es adoptar un estándar o modelo para garantizar la calidad de sus productos. Sin embargo, este tipo de organización, carece o no tienen procesos bien definidos. En este contexto implementar un modelo o estándar de calidad para estas organizaciones enfrenta algunos obstáculos como: gran desconocimiento sobre éstos, su adopción representa una curva de aprendizaje prolongado, las certificaciones de estos modelos o estándares para las pymes y su personal representan costos muy elevados. Por lo tanto, en este artículo se presenta una herramienta ontológica basada en el Modelo CMMI-DEV v1.3. El objetivo principal es proveer a las pymes de una herramienta que contraste sus procesos actuales obtenidos a través de un método para la extracción del conocimiento tácito versus los procesos de CMMI-DEV v1.3 para detectar posibles hallazgos de mejora e implementar mejoras en sus procesos organizacionales.

  4. Relancer Saint-Étienne. Conditions institutionnelles et capacité d’action collective dans une ville en déclin

    Directory of Open Access Journals (Sweden)

    Vincent Béal

    2010-11-01

    Full Text Available L'objectif de cet article est de comprendre comment une capacité d’action collective peut se construire dans une ville marquée par une industrialisation ancienne et, plus récemment, par un déclin démographique et économique. La thèse principale de l'article, inspirée par l’économie politique et le néo-institutionnalisme, est que la difficulté d’un territoire d’ancienne industrialisation à constituer une capacité d’action collective peut certes s’expliquer par une position défavorable dans la nouvelle division internationale du travail mais aussi par les conditions institutionnelles engendrées par ce passé industriel et la crise économique et démographique. Dans le cas de Saint-Étienne analysé dans cet article, les modalités historiques de l’industrialisation mais aussi les modalités de gestion de la crise de désindustrialisation ont engendré des conditions institutionnelles –dispositions à la prise de parole età la coopération, nature des rapports entre les différents types d’organisation (milieux économiques, classe politique locale, État- peu favorables à l’émergence d’une capacité d’action collective et à l’élaboration de stratégies partagées de sortie de crise.The objective of the article is to understand how a political capacity can emerge in a city characterised by an ancient process of industrialisation and, more recently, by an economic and demographic decline. The central thesis of the article is inspired by political economy and neo-institutionalism. One considers that the difficulties faced by a place of old industry to build up a political capacity can admittedly be explained by an unfavourable position in the international division of labour but also the institutional conditions generated by the industrial past and the economic and demographic crisis. In the case of the French city of Saint-Étienne, analysed in this article, the historical modalities in which

  5. La susceptibilidad magnética del batolito de Achala (Devónico, Sierra Grande de Córdoba y sus diferencias con otros granitos achalianos

    Directory of Open Access Journals (Sweden)

    Silvana E. Geuna

    2008-09-01

    Full Text Available El magmatismo devónico de las Sierras Pampeanas de Córdoba y San Luis está representado por batolitos y plutones de composición monzogranítica y forma subelíptica, emplazados en un basamento metamórfico-plutónico eopaleozoico. Se distinguen dos grupos: el primero, compuesto por granitoides con hornblenda-biotita, metaluminosos a débilmente peraluminosos; y el segundo, formado por granitoides con biotita y muscovita, peraluminosos. Ambos grupos se caracterizan respectivamente por tener magnetita e ilmenita como fases accesorias, lo cual genera propiedades magnéticas distintivas. Entre ellos, el batolito de Achala, Córdoba, con una extensión de casi 2.500 km², es un buen exponente de los granitos paramagnéticos (no magnéticos. Su mineralogía magnética fue caracterizada en cuarenta y un sitios, la mayoría de ellos en el Monzogranito Achala. Se determinó una susceptibilidad magnética promedio muy baja, 15 x 10-5 (SI, controlada por el contenido de biotita e ilmeno- hematita. Veintiún sitios mostraron remanencia magnética estable portada por hematita, que aparece como un mineral accesorio, intercrecida con discos de exsolución de (hemoilmenita. La anisotropía de susceptibilidad magnética es débil y predominan las formas obladas, como es usual en fábricas magmáticas de granitos paramagnéticos; casi no se obtuvieron lineaciones. El grado de anisotropía es mayor en zonas con cizallamiento magmático, debido al efecto de la deformación subsolidus. El magnetismo débil del monzogranito de Achala contrasta con el carácter magnético de los plutones monzograníticos porfíricos más representativos de otros batolitos de la región, como Renca, Cerro Áspero y Las Chacras-Piedras Coloradas. La virtual ausencia de magnetita, junto con la presencia de ilmeno-hematita exsuelta, indica que un enfriamiento bajo condiciones oxidantes sería el responsable del carácter paramagnético de Achala. Como consecuencia de aplicación pr

  6. Ivan Grohar and Oskar Dev – An Interdisciplinary and Multidisciplinary Fragment Comparison of Their Artistic Works in Škofja Loka/Slovenia (1905-1911

    Directory of Open Access Journals (Sweden)

    Franc Križnar

    2014-12-01

    Full Text Available The new Grohar’s room in the Škofja Loka Mu¬seum that is located in a more than a thousand years old town, some kilometres northwest of Ljubljana, Slove¬nia, represents one of the new possibilities to popularize old local history. Ivan Grohar (1867−1911 is one of the four well-known Slovenian painters from the beginning of the 20th century, together with Rihard Jakopič, Matija Jama and Matej Sternen. These Slovenian painters are the founders of Impressionism within the modern style. Škofja Loka became the so called Slovenian “Barbizon” (i.e. French village near Fontainebleau, once the settle-ment of painters and this art and old tradition inspired another Slovenian (music artist Oskar Dev (1868−1932, who composed some of his musical works (songs and choirs in Škofja Loka, too. His and Grohar’s period in Škofja Loka resulted in some extraordinary art works i.e. paintings and musical works. They both were inspired by the countryside that reflected on their works. This is now one of the new Slovenian’s challenges of museology and musicology in an interdisciplinary and multidisciplinary approach so the art of painting and music could be a benefit for the visitors of this and other museums.

  7. Spoločenstvá suchozemských mäkkýšov severnej časti Devínskej Kobyly (Malé Karpaty

    Directory of Open Access Journals (Sweden)

    Jozef Šteffek

    2005-11-01

    Full Text Available Present paper is focused on two topics. First topic is focused on evaluation of mollusc assemblages of northern part of the Devínska Kobyla hill (Malé Karpaty Mts.. The second topic was evaluation of all published data on molluscs of this area. The research was conducted during vegetation period of the year 1978. From 9 types of biotopes altogether 47 quantitative samples were sampled. The assemblages were evaluated on the base of constancy and dominance of the species. Altogether 7913 mollusc specimens were obtained from the samples. Composition and status of the forest mollusc assemblages in northern part of the Devínska Kobyla was shown to be determined by the substratum, age of forest stand and the degree of the biotopes disturbance. The species richest assemblage was detected within old grown forest (biotope 7 and calcareous substratum. The species poorest were assemblages found within clear-cut and young stand (biotopes 5, 8. Species rich community was found also in old growth forest with quartzite substratum, however a number of steppe species is absent within this biotope. The molluscan communities of open habitats were observed only in the northern part of the Devínska Kobyla foothill area. They occur mainly within xeric degraded grassland biotopes (vacant pastures, deforested fields. Within other non-limestone substratum biotopes only species poor coenoses composed of single or e few of species occurred (biotopes 2 and 6. The exception was the natural xeric grassland biotopes, which were typical biotopes for rich community of steppe molluscs (biotope 9. Extremely rich were limestone rocks, which are in addition partially covered by forest. The rich forest land snail community together with a number of xeric species was found here (biotope 3. In second part mollusc species composition of northern and southern part of the Devínska Kobyla massive and the Devínske Hradné Bralo hill are compared. Altogether 65 mollusc species (51

  8. Green House Angel&Dev

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    这个叫做Angel&Devil的可爱小东西,是GreenHouse公司推出的新款时尚型入耳式耳机。这款耳机右耳是天使的造型,左耳则设计成魔鬼的样子,共有5款颜色可以选择。这耳机的接口处均进行了镀金处理,频率响应为20Hz-20000Hz,阻抗为16欧姆,输入功率最大5mW。

  9. Devónico de la Sierra de la invernada, precordillera de San Juan, Argentina: revisión estratigráfica e implicancias paleogeográficas

    Directory of Open Access Journals (Sweden)

    Silvio H Peralta

    2013-06-01

    Full Text Available En este trabajo se describe e interpreta desde punto de vista estratigráfico la sucesión marino-clástica del Devónico expuesta en el flanco oriental de la Sierra de la Invernada, desde el área de Gualilán, al norte, hasta el área de Pachaco, al sur, Precordillera Central de San Juan. La aludida sucesión está integrada por las formaciones Punta Negra (Emsiano-Eifeliano? y Los Sombreros (ex "Formación Corralito" (Devónico post-Formación Punta Negra, destacándose en el área la ausencia de la Formación Talacasto (Lochkoviano - Emsiano cuyos depósitos se encuentran resedimentados en los olistostromas de la Formación Los Sombreros. La Formación Punta Negra presenta arreglo general estrato-granocreciente; en el área de Gualilán, sobreyace en paraconcordancia a la Formación Los Espejos, mientras que en el área de Pachaco sobreyace a la Formación Los Bretes (Hirnantiano a Wenlokiano, evidenciando un hiatus que incluye a las formaciones Los Espejos y Talacasto. En toda el área de estudio, la Formación Punta Negra se observa cubierta en paraconcordancia (superficie erosiva por depósitos de olistostroma de la Formación Los Sombreros, los cuales, sobre la base de sus relaciones estratigráficas, características litológicas y paleobiológicas, se sugiere serían el resultado de un evento distensivo acaecido en el Devónico post-Formación Punta Negra. La falta de registro de la Formación Talacasto se interpreta como resultado del basculamiento de la cuenca Devónica hacia el norte, debido al control del Alto del Tambolar.

  10. Spoločenstvá suchozemských mäkkýšov severnej časti Devínskej Kobyly (Malé Karpaty)

    OpenAIRE

    Jozef Šteffek

    2005-01-01

    Present paper is focused on two topics. First topic is focused on evaluation of mollusc assemblages of northern part of the Devínska Kobyla hill (Malé Karpaty Mts.). The second topic was evaluation of all published data on molluscs of this area. The research was conducted during vegetation period of the year 1978. From 9 types of biotopes altogether 47 quantitative samples were sampled. The assemblages were evaluated on the base of constancy and dominance of the species. Altogether 7913 mollu...

  11. Geología y petrología del granito tres cerritos, extremo meridional de la sierra de Quilmes y su relación con el magmatismo devónico-carbonífero de las sierras Pampeanas

    Directory of Open Access Journals (Sweden)

    Ana E Acosta Nagle

    2014-09-01

    Full Text Available El Granito Tres Cerritos está ubicado en el extremo SE de la Sierra de Quilmes, en el departamento Santa María, provincia de Catamarca, en el ambiente morfoestructural de Sierras Pampeanas Septentrionales. El basamento metamórfico de la zona de estudio está constituido por esquistos de bajo y mediano grado metamórfico pertenecientes al Complejo Tolombón, que son afectadas por una faja de cizalla formada con anterioridad al emplazamiento del intrusivo. Localmente se produce metamorfismo de contacto con formación de porfiroblastos de cordierita y biotita. El granito Tres Cerritos aflora en dos sectores, uno de mayor extensión, de unos 6 km² de superficie, de forma elongada con su eje mayor de 4 km de rumbo submeridional y otro más pequeño, que aflora al oeste del área de estudio, de unos 1,9 Km de largo por 250 m de ancho, aproximadamente. Composicionalmente varía entre sienogranito y monzogranito y presenta tres facies: Porfírica biotítica, porfírica moscovítica y equigranular moscovítica. Geoquímicamente se define como un granito calco-alcalino y peraluminoso, con alto potasio. Según dataciones K/Ar este granito sería de edad carbonífera superior. Las características petrográficas, geoquímicas y geocronológicas del granito Tres Cerritos son similares a la de los intrusivos devónico-carboníferos de las Sierras Pampeanas de Catamarca, La Rioja, Córdoba y San Luis, por lo que el granito Tres Cerritos formaría parte de un evento magmático de gran extensión areal, post-orogénico o de intraplaca, que afectó a las Sierras Pampeanas durante el Devónico-Carbonífero.

  12. Point of Care Tools im Vergleich des Universitätsklinikums Hamburg-Eppendorf (UKE: UpToDate, ClinicalResource@Ovid/Clin-eguide und Dynamed / Point of Care Tools in comparison at the University Medical Center Hamburg-Eppendorf: UpToDate, ClinicalResource@Ovid and Dynamed

    Directory of Open Access Journals (Sweden)

    Menn, Elke

    2006-09-01

    Full Text Available Point of Care Tools are used for clinical decision making – UpToDate is also used in continuing medical education. These databases compile only evidence-based knowledge which is updated regularly. Using Point of Care Tools promises to improve clinical outcomes. UpToDate has been used at the University Hospital Hamburg-Eppendorf for the last four years. In a recent trial the use of ClinicalResource@Ovid/Clin-eguide and Dynamed has been evaluated in comparison with UpToDate.

  13. Fıtrat Hadisi’nin Osmanlı'nın Devşirme Sisteminde Hayata Aksedişi 'The Hadith of Fitrah’ And How It Is Reflected On Life Ottoman’s Devshirme System

    Directory of Open Access Journals (Sweden)

    Mustafa IŞIK

    2013-07-01

    -culture on thisevent with together ‘Devshirme’. ‘Her çocuk, fıtrat üzere doğar; sonra onu ana-babası Yahudileştirir, Hıristiyanlaştırır veya Mecusîleştirir’ hadisi, temel İslam bilimlerinde ‘fıtrat hadisi’ olarak bilinir. İslami literatürde, geçmişten günümüze, bu hadis hakkında çeşitli görüşler ortaya konmuştur. Fıtrat hadisinin, klasik hadis literatüründeki kaynakları ve hadis imamlarının bu hadise bakışları açısından daha çok ‘Çocuğun ölmesi halinde dinî ve hukukî durumunun ne olacağı?’ sorusu üzerinde durulmuştur. Ancak hadis bilginleri ve bazı interdisipliner İslam âlimleri, fıtrat’ın ‘insanlığın ortak dinî temeli’ olduğuna inanmaktadırlar. Bu görüşe bağlı olarak biz, fıtrat hadisi’nin Osmanlı’daki ‘devşirme’ hadisesiyle örtüştüğünü düşünüyoruz. Devşirme sisteminin, tarihi bir olgu olarak, Osmanlı’da gerçekleşen halini ele almak istiyoruz. Bu haliyle Osmanlı Devleti bu olguyu sistemleştirip kanun, tüzük ve yönetmeliği olan bir sistem haline koymadan önce dini yönünü hesaba kattığını; bu hadisteki ‘fıtrat gerçeği’nden hareket etmiş olabileceğini; güçlü kaslar ve çalışkan beyinler sayesinde özelde devletine genelde insanlığa hizmet ettiğini var sayıyoruz. O günün dünya devleti olan Osmanlı’dan bugünün dünya devleti ABD’ye baktığımızda, işleyiş ve yöntem farklı olsa da, birtakım paralellikler görmekteyiz. Farklı asırlarda, değişik coğrafyalarda, birbirine benzemeyen iki büyük medeniyetin ortaya koyduğu uygulamadaki benzerlik ve ulaştığı ortak nokta, eğitimin, başat belirleyici olduğu gerçeğidir. Bu makalenin amacı, sadece tarihî bir fenomeni dile getirmek değil; fıtratın anlamını, geçerliliğini bu tarihî olgudan hareketle yinelemektir. Makalemizde bu konuyu fıtrat yani insanın değişmeyen varlık yapısı ve eğitim-kültürün bu yapıya etkisini ‘devşirme’ olgusuyla

  14. ComDev in the Mediatized World

    DEFF Research Database (Denmark)

    Tufte, Thomas; Hemer, Oscar

    2012-01-01

    revolution are rightfully refuted, the on-going Arab Spring is a clear-cut example of an unprecedented communication power, largely out of the authorities’ control. While the crucial role of media and communication in processes of social change at last becomes evident, it is however not associated...

  15. Forcecom Developer Certification Handbook (DEV401)

    CERN Document Server

    Kabe, Siddhesh

    2012-01-01

    A practical guide that will help you discover fundamentals for building applications on Force.com without writing a single line of code. If you are new to the Force.com platform and want to learn from scratch, it is advisable that you begin with the first chapter and move on to the last. However, if you are familiar with Force.com and want to understand in detail some aspect of it, you can dip into any chapter. Each certification module is covered in a separate chapter, and is accompanied by questions being asked in the exams. Developers who need to prepare for the Salesforce.com Certified For

  16. Disease: H00093 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available , Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) ...312863 613179 603554 233650 612782 612783 PMID:17162365 (gene) Kumar A, Teuber SS

  17. Disease: H00087 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available in lymphocytes. N Engl J Med 343:1313-24 (2000) PMID:17162365 (description, gene) Kumar A, Teuber SS, Gershwin ME. Current perspecti...ves on primary immunodeficiency diseases. Clin Dev Immun

  18. Disease: H00256 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ndromes. Endocr Dev 13:99-116 (2008) PMID:17161331 Metherell LA, Chan LF, Clark AJ The genetics of ACTH resistance syndromes. Best Pract Res Clin Endocrinol Metab 20:547-60 (2006) ...

  19. Point-of-Care Healthcare Databases Are an Overall Asset to Clinicians, but Different Databases May Vary in Usefulness Based on Personal Preferences. A Review of: Chan, R. & Stieda, V. (2011. Evaluation of three point-of-care healthcare databases: BMJ Point-of-Care, Clin-eguide and Nursing Reference Centre. Health and Information Libraries Journal, 28(1, 50-58. doi: 10.1111/j.1471-1842.2010.00920.x

    Directory of Open Access Journals (Sweden)

    Carol D. Howe

    2011-01-01

    Full Text Available Objective – To evaluate the usefulness of three point-of-care healthcare databases (BMJ Point-of-Care, Clin-eguide, and Nursing Reference Centre in clinical practice.Design – A descriptive study analyzing questionnaire results.Setting – Hospitals within Alberta, Canada’s two largest health regions (at the time of this study, with a third health region submitting a small number of responses.Subjects – A total of 46 Alberta hospital personnel answered the questionnaire, including 19 clinicians, 7 administrators, 6 nurses, 1 librarian, 1 preceptor, and “some” project coordinators. Subjects were chosen using a non-probability sampling method.Methods – The researchers developed an online questionnaire consisting of 17 questions and posted it on the University of Calgary’s Health Sciences Library and the Health Knowledge Network websites. The questions, in general, asked respondents how easy the databases were to search and use, whether the database content answered their clinical questions, and whether they would recommend the databases for future purchase. Most questions required a response for each of the three databases. The researchers collected quantitative data by using a Likert scale from 1 to 5, with 5 being the most positive answer and 1 being the most negative. They collected qualitative data by asking open-ended questions.Main Results – With regard to ease of searching, BMJ Point-of-Care (BMJ received the greatest number of responses (71% at level 5. A smaller number of respondents (56% rated Nursing Reference Centre (NRC at level 5. Clin-eguide received 59% of the responses at level 5, but it also received the greatest number of responses at the next highest level (level 4. Respondents rated all three databases similarly with regard to levels 1 and 2.Regarding how easy the resources were to learn, most respondents rated all three databases as easy to learn (BMJ, 77%; Clin-eguide, 72%; and NRC, 68%. Very few respondents

  20. Pilkupüüdev seltsidaam / Aare Ermel

    Index Scriptorium Estoniae

    Ermel, Aare, 1957-2013

    2006-01-01

    Shoti päritolu näitlejanna Lindsay Duncan, kes kehastab ajaloolises teleseriaalis "Rooma" (tootjad Ameerika HBO, inglaste BBC ja itaallaste RAI) Gaius Julius Caesari kättemaksuhimulist armukest Serviliat. Sama ka : Teleleht nr. 50, lk.38 : ill

  1. Modelización genética de nódulos silíceos: aplicación al Devónico de Tabuenca (Cordillera Ibérica, España. I: Caracterización morfológica y composicional

    Directory of Open Access Journals (Sweden)

    Bona Artazos, M. E.

    2005-04-01

    Full Text Available Siliceous nodules of the Devonian deposits in the «Hoya Formation» (Tabuenca-Zaragoza have been studied. The nodules are included in lutites, and contain quartz, opaque minerals and clays. The cement is criptocrystalline quartz. Our morphologic study reveals that these are spheres and spheroids, with a gray colour and 0.3 to 9.6 cm of diameter, and grade into the direction of stratification. This spherical morphology is the result of isotropic structure of host sediment, and it indicates a growth mechanism by diffusion and a short transport mechanism. The existence of distorted lamination indicate that its central section was cemented before its outer section, and that its growth was passive, by a mechanism of porosity-grouth filling.Se han caracterizado morfológica y composicionalmente los nódulos silíceos que aparecen en los materiales pelíticos de la Formación Hoya (Devónico superior, en las proximidades de la localidad zaragozana de Tabuenca. Los nódulos se localizan entre capas de lutitas, y están compuestos por cuarzo criptocristalino, minerales arcillosos (caolinita principalmente, minerales opacos y restos fósiles. El estudio morfológico llevado a cabo revela que estas estructuras son esferas y esferoides, de color gris y con diámetro variable entre 0,3 y 9,6 cm. Además es destacable que se presentan con la misma orientación que la estratificación. Su morfología se explica producida por la estructura isótropa del sedimento hospedante, y ello indica que estas estructuras crecieron mediante un mecanismo de difusión y un transporte relativamente corto. La existencia de una laminación deformada alrededor de ellos mostraría que su parte central fue cementada, antes que la parte exterior, de manera pasiva mediante un mecanismo de crecimiento por relleno de porosidad.

  2. La susceptibilidad magnética del batolito de Achala (Devónico, Sierra Grande de Córdoba y sus diferencias con otros granitos achalianos The magnetic susceptibility of the Achala Batholith (Devonian, Sierra Grande de Córdoba and its difference with other Achalian granites

    Directory of Open Access Journals (Sweden)

    Silvana E. Geuna

    2008-09-01

    Full Text Available El magmatismo devónico de las Sierras Pampeanas de Córdoba y San Luis está representado por batolitos y plutones de composición monzogranítica y forma subelíptica, emplazados en un basamento metamórfico-plutónico eopaleozoico. Se distinguen dos grupos: el primero, compuesto por granitoides con hornblenda-biotita, metaluminosos a débilmente peraluminosos; y el segundo, formado por granitoides con biotita y muscovita, peraluminosos. Ambos grupos se caracterizan respectivamente por tener magnetita e ilmenita como fases accesorias, lo cual genera propiedades magnéticas distintivas. Entre ellos, el batolito de Achala, Córdoba, con una extensión de casi 2.500 km², es un buen exponente de los granitos paramagnéticos (no magnéticos. Su mineralogía magnética fue caracterizada en cuarenta y un sitios, la mayoría de ellos en el Monzogranito Achala. Se determinó una susceptibilidad magnética promedio muy baja, 15 x 10-5 (SI, controlada por el contenido de biotita e ilmeno- hematita. Veintiún sitios mostraron remanencia magnética estable portada por hematita, que aparece como un mineral accesorio, intercrecida con discos de exsolución de (hemoilmenita. La anisotropía de susceptibilidad magnética es débil y predominan las formas obladas, como es usual en fábricas magmáticas de granitos paramagnéticos; casi no se obtuvieron lineaciones. El grado de anisotropía es mayor en zonas con cizallamiento magmático, debido al efecto de la deformación subsolidus. El magnetismo débil del monzogranito de Achala contrasta con el carácter magnético de los plutones monzograníticos porfíricos más representativos de otros batolitos de la región, como Renca, Cerro Áspero y Las Chacras-Piedras Coloradas. La virtual ausencia de magnetita, junto con la presencia de ilmeno-hematita exsuelta, indica que un enfriamiento bajo condiciones oxidantes sería el responsable del carácter paramagnético de Achala. Como consecuencia de aplicación pr

  3. Disease: H00098 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00098 Chronic granulomatous disease, including the following four diseases: X-link...65 Kumar A, Teuber SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immu...ifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of I

  4. Disease: H00086 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00086 Hyper IgM syndromes, autosomal recessive type, including the following three diseases...tives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:18424339 (gene) Morra M, ...er A, Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases

  5. Disease: H00089 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00089 IFN-gamma/IL-12 axis, including the following five diseases: IL-12 p40 subun...rrent perspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:18424339 (ge...R, Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of Immunological So

  6. Disease: H00103 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00103 Late complement pathway defects, including the following seven diseases: C5 ...Current perspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:22...rstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: a

  7. Disease: H00104 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00104 Alternative complement pathway component defects, including the following four diseases...primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:17952897 (gene) Geha RS, Notarange...hs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the Intern

  8. PAEDIATRIC POSTERIOR FOSSA TUMORS: A CLIN ICO - PATHOLOGICAL STUDY I N A TERTIARY CARE HOSPITAL

    Directory of Open Access Journals (Sweden)

    Raja Sekhar Kennedy

    2015-09-01

    Full Text Available INTRODUCTION: Tumors of the Central Nervous S ystem , are the second commonest childhood tumors and are the most common solid paediatric tumors comprising 40% - 50% of all tumors . 1 2 Posterior fossa brain tumors are one of the most devastating forms of human illnesses wh ich are more common in children. AIMS AND OBJECTIVES : To study the incidence, clinicopathological features and management of paediatric posterior fossa tumors. MATERIALS AND METHOD S : This is a prospective study done in the Department of Neurosurgery, Ranga raya Medical College, Government General Hospital, Kakinada from 2012 to 2015. It is a Tertiary Care Hospital. A total of 25 paediatric patients ranging from infants to 15 years were included in the study. DISCUSSION AND CONCL USION: Posterior fossa tumors are the commonest solid brain tumors of children with a rate of 2.4 per lakh of children at risk per year. The predominant symptoms are headache and vomiting followed by cerebellar symptoms (gait disturbances. Posterior fossa tumors are predominantly seen in children with peak incidence in first decade. Commonest presenting symptoms are due to raised intracranial pressure with headache and vomiting followed by cerebellar symptoms. Meticulous microsurgical techniques are to be followed in removing these tum ors. The incidence of recurrence is very less after gross total excision. Prognosis is good in patients with total excision

  9. Le Déclin de l’intelligentsia de gauche en Irak

    OpenAIRE

    Salaam Yousif

    2012-01-01

    Durant les années 1940 et 1950, l’intelligentsia de gauche a joué un rôle remarquable dans la construction d’une culture irakienne vibrante, a contribué à la floraison de la littérature et des arts et a exercé une influence majeure dans les sphères politique et culturelle. Cet article se centre principalement sur les années 1960 quand, malgré deux coups d’État baassistes, l’atmosphère culturelle était clairement de gauche. La seconde moitié de la décennie a été marquée par un élan vers la gau...

  10. Acides gras oméga-3 et déclin cognitif : la controverse

    Directory of Open Access Journals (Sweden)

    Barberger-Gateau Pascale

    2013-03-01

    Full Text Available Basic research suggests a protective effect of the long-chain omega-3 polyunsaturated fatty acids – eicosapentaenoic acid (EPA and docosahexaenoic acid (DHA – against brain aging. In humans, many epidemiological studies have found an inverse association between fish consumption or high blood levels of EPA and DHA, and cognitive decline or risk of dementia. However, most randomized controlled trials with EPA and/or DHA supplements have failed to show any impact on cognitive decline. This paper analyses several reasons for such inconsistent results, including the time and duration of the supplementation, the cognitive and dietary inclusion criteria, the optimal doses of EPA and DHA, the interaction with genetic polymorphisms, and the need to consider synergistic effects between nutrients as they are provided by healthy diets.

  11. Disease: H01362 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 0: L13.0 PMID:22811741 (gene, env_factor) Nakajima K Recent advances in dermatitis herpetiformis. Clin Dev I..., Hissa-Elian A, de Abreu MA, Goncalves VS Review: dermatitis herpetiformis. An Bras Dermatol 88:594-9 (2013...76 (drug) Caproni M, Antiga E, Melani L, Fabbri P Guidelines for the diagnosis and treatment of dermatitis herpetiformis. J Eur Acad Dermatol Venereol 23:633-8 (2009) ...

  12. Disease: H00102 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00102 Classic complement pathway component defects, including the following eight diseases...h increased risk to develop systemic lupus erythematosus (SLE) and SLE-like diseases... Kumar A, Teuber SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immuno...imary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary I...pel H, Conley ME, Fischer A, Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Pr

  13. Disease: H00100 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00100 Neutropenic disorders, including the following three diseases: Kostmann synd...rspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:15096561 Lim MS, Ele...ME, Fischer A, Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases...D:19811314 Rezaei N, Moazzami K, Aghamohammadi A, Klein C Neutropenia and primary immunodeficiency diseases. Int Rev Immunol 28:335-66 (2009) ...

  14. Disease: H00105 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00105 Mannose-binding lectin pathway component defects, including the following two diseases...ering MC, Wurzner R, Tedesco F Complement in human diseases: Lessons from complement deficiencies. Mol Immun... Kumar A, Teuber SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immuno...imary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary I..., Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Pr

  15. The role of positive emotions within parenting interventions as part of therapeutic change

    OpenAIRE

    Macdonald, Wendy J

    2014-01-01

    AbstractParenting and Positive EmotionsThe University of ManchesterWendy Jane MacdonaldDoctor of Clinical Psychology, ClinPsyDJanuary 2014This thesis has considered findings from evaluations of parenting programmes which have traditionally used outcome measures of negative affect and behaviour to measure change. Drawing on the considerable body of research on parenting programmes and their theoretical basis Paper 1 advances a line of argument about the potential for incorporating measures dev...

  16. Dev konka bülloza içinde fungus topu: Olgu sunumu,

    OpenAIRE

    Acar, A.; Uyar, M; Açıkalın, A.; E.Dursun; , S.Kurukahvecioğlu; Eryılmaz, A.

    2013-01-01

    Concha bullosa is one of the most common nasal anatomic variations. The size of concha bullosa is important factor in its symptomatic situation. Fungus ball is extramucosal and noninvasive accumulations of degenerating fungal hyphae. It is most common occur form in fungal sinusitis. The fungus ball is mostly caused by Aspergillus spp. In this case report, we present a rare fungus ball case which is localized chonca bullosa. Eight-teen years-old female patient was admitted to our clinic. She h...

  17. $V_DEV$ divisore di frequenza programmabile in standard VME 6U

    CERN Document Server

    Paoluzzi, G

    1999-01-01

    Modulo a 32bit programmabile tramite bus VME, divisore di frequenza a 4 canali per segnali sinusoidali e digitali nello standard NIM, utilizzato per le frequenze di acquisizione nell¹esperimento NAUTILUS.

  18. Pro website development and operations streamlining DevOps for large-scale websites

    CERN Document Server

    Sacks, Matthew

    2012-01-01

    Pro Website Development and Operations gives you the experience you need to create and operate a large-scale production website. Large-scale websites have their own unique set of problems regarding their design-problems that can get worse when agile methodologies are adopted for rapid results. Managing large-scale websites, deploying applications, and ensuring they are performing well often requires a full scale team involving the development and operations sides of the company-two departments that don't always see eye to eye. When departments struggle with each other, it adds unnecessary comp

  19. Émergence et déclin de la gouvernance démocratique en droit international

    NARCIS (Netherlands)

    J. d' Aspremont

    2009-01-01

    This article argues that the years 1989-2010 can be hailed as an unprecedented epoch of international law during which domestic governance - understood here in a traditional way as the use of public authority at the domestic level through a central governmental authority - came to be regulated to an

  20. De la promotion à la relégation. Le déclin des CAP de couture

    OpenAIRE

    Divert, Nicolas

    2013-01-01

    Il y a un siècle, la naturalisation du lien entre les filles et la couture rend légitime leur orientation dans les CAP de cette spécialité. Ce faisant, elles accèdent à l’enseignement professionnel qui les maintenait à sa périphérie. Mais alors que les CAP sont construits théoriquement à partir de liens étroits avec l’emploi, des déterminants politiques, économiques ou sociaux apparaissent majeurs pour saisir la construction, l’évolution et le maintien d’une offre de formation initiale. Si ce...

  1. What Clinical Interventions Have Been Implemented to Prevent or Reduce Postpartum Hypertension Readmissions? A Clin-IQ

    Science.gov (United States)

    O’Meara, Sara; Lepic, Molly

    2016-01-01

    A literature review was conducted to determine what clinical interventions have been studied and implemented to prevent and/or reduce postpartum hypertension readmissions. Appropriate verbal and printed educational materials should be given to the patient prior to discharge with use of the “teach back” method. Patients and health care providers within the multidisciplinary team should be educated on the warning signs and symptoms of worsening hypertensive disease and when to appropriately involve the obstetrician. The use of text messaging may be useful in preventing hospital readmissions by increasing patient follow-up and compliance and appropriately managing patients in the postpartum period. Treating postpartum patients with furosemide may decrease blood pressure and prevent postpartum hypertension and the need for antihypertensive therapy.

  2. Which Clinical Guidelines Should Be Implemented for Management of Osteopenia in Primary Care? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Turia Hollingsworth

    2014-11-01

    Full Text Available Literature review was conducted to determine clinical guidelines for osteopenia management of immunocompetent patients in the primary care setting. It was concluded that pharmacological treatment should be offered to patients with osteopenia if they are considered high risk, which can be determined by utilizing the World Health Organization Fracture Risk Assessment Tool (FRAX® to evaluate 10-year risk. Patients with a calculated hip fracture probability of at least 3% or those with probability of 20% or more for all osteoporotic fractures may be offered bisphosphonate therapy.

  3. Should Primary Care Physicians Address Sleep to Improve Weight Loss in Obese Patients? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Kjersti E. Knox

    2015-11-01

    Full Text Available Obesity is a commonly encountered problem in the primary care setting. Simultaneously, sleep is seen to hold an increasingly important role in many components of health and wellness. A review of the literature was performed to determine if improving sleep positively impacts weight loss in obese adults. The evidence reviewed suggests that improving patients’ sleep may initially improve patient weight loss; however, current studies do not show a sustained statistically significant impact. Until higher powered and higher quality studies are completed, there are no clear evidence-based guidelines for primary care physicians to follow regarding sleep and obesity.

  4. Drug education in victorian schools (DEVS: the study protocol for a harm reduction focused school drug education trial

    Directory of Open Access Journals (Sweden)

    Midford Richard

    2012-02-01

    Full Text Available Abstract Background This study seeks to extend earlier Australian school drug education research by developing and measuring the effectiveness of a comprehensive, evidence-based, harm reduction focused school drug education program for junior secondary students aged 13 to 15 years. The intervention draws on the recent literature as to the common elements in effective school curriculum. It seeks to incorporate the social influence of parents through home activities. It also emphasises the use of appropriate pedagogy in the delivery of classroom lessons. Methods/Design A cluster randomised school drug education trial will be conducted with 1746 junior high school students in 21 Victorian secondary schools over a period of three years. Both the schools and students have actively consented to participate in the study. The education program comprises ten lessons in year eight (13-14 year olds and eight in year nine (14-15 year olds that address issues around the use of alcohol, tobacco, cannabis and other illicit drugs. Control students will receive the drug education normally provided in their schools. Students will be tested at baseline, at the end of each intervention year and also at the end of year ten. A self completion questionnaire will be used to collect information on knowledge, patterns and context of use, attitudes and harms experienced in relation to alcohol, tobacco, cannabis and other illicit drug use. Multi-level modelling will be the method of analysis because it can best accommodate hierarchically structured data. All analyses will be conducted on an Intent-to-Treat basis. In addition, focus groups will be conducted with teachers and students in five of the 14 intervention schools, subsequent to delivery of the year eight and nine programs. This will provide qualitative data about the effectiveness of the lessons and the relevance of the materials. Discussion The benefits of this drug education study derive both from the knowledge gained by trialling an optimum combination of innovative, harm reduction approaches with a large, student sample, and the resultant product. The research will provide better understanding of what benefits can be achieved by harm reduction education. It will also produce an intervention, dealing with both licit and illicit drug use that has been thoroughly evaluated in terms of its efficacy, and informed by teacher and student feedback. This makes available to schools a comprehensive drug education package with prevention characteristics and useability that are well understood. Trial registration Australia and New Zealand Clinical Trials Register (ANZCTR: ACTRN12612000079842

  5. Ayak Küboid Kemiğinde Lokalize Dev Hücreli Tümör

    OpenAIRE

    Yazicioglu, O.; Kokino, M.; Temelli, Y.; Tozun, R.; Domanic, U.; Turkmen, M.; Ozger, H.

    2004-01-01

    Attempts have been made to review 36 giant cell tumours treated surgicaly in the Department of Orthopaedics and Traumotology of the İstanbul Medical School of İstanbul Universty, beetween 1970-1983 years and after making researchs in literature it has been found conviniend to report a giant cell tumour localized in cuboid bone of the foot as it is seen the first time both in literature and among our clinical cases.

  6. Disease: H00101 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00101 Other phagocyte defects, including the following eight diseases: Chediak-Hig...lobulinemia and pancytopenia. Abnormal-beta-actin disease accompanies neutrophil ...which is usually triggered by an exogenous agent. Shwachman-Diamond syndrome (SDS) is a rare autosomal-recessive, multisystem disea...on, gene) Nunoi H, Yamazaki T, Kanegasaki S Neutrophil cytoskeletal disease. Int J Hematol 74:119-24 (2001) ...n primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:9737224 (gene) Ten RM. Primary i

  7. L’essor et le déclin de la stratégie économique keynésienne – structuraliste au Mexique

    OpenAIRE

    López G., Julio

    2012-01-01

    Pendant au moins deux décennies après la seconde guerre mondiale, la croissance économique au Mexique a été très rapide, à tel point que pour la caractériser, le terme « miracle mexicain » a été introduit. Le but de ce travail est d’étudier les causes immédiates ainsi que les origines historiques de l’essoufflement du miracle mexicain. L’auteur examine les limites de la stratégie fondée sur la substitution des importations en prenant en compte aussi bien des problèmes du côté de l’offre que d...

  8. Les chaîniers français (1823-2005. De l’essor au déclin

    Directory of Open Access Journals (Sweden)

    Edgard Strigler

    2011-05-01

    Full Text Available Composition du juryMonsieur Marc de Beauregard, PDG de Sedis de 1991 à 1993,Monsieur Michel Cotte, professeur émérite, Université de Nantes,Monsieur Alain Dewerpe, directeur d’études, ÉHESS,Monsieur Patrick Fridenson, directeur de thèse, directeur d’études, ÉHESS,Monsieur Hervé Joly, directeur de recherche, CNRS,Monsieur Pierre Lamard, professeur, ,Université de Technologie de Belfort-Montbéliard,Monsieur Denis Woronoff, professeur émérite, Université de Paris I.Thèse soutenue le 20 janvier 2...

  9. [Nutrition and child development I; nutritional status of school children in a peripheral district of Madrid (Rev Clin Esp 1944; XII:87-94)].

    Science.gov (United States)

    Grande Covián, F; Rof Carballo, J; Jiménez García, F; Morata Cernuda, A

    2014-09-01

    El estudio clínico del estado nutritivo de un grupo de niños en edad escolar, habitantes de un suburbio madrileño revela la existencia, relativamente rara, de signos carenciales específicos, que contrasta vivamente con el considerable retraso que se observa en su desarrollo somático. Los hechos parecen demostrar que el problema nutritivo de estos niños es sobre todo un problema cuantitativo. El retraso de la evolución está en relación con la insuficiencia global de la dieta y con el déficit de calcio que es probablemente el elemento individual con mayor grado de carencia en las dietas. La anemia que presenta el 98% de los niños no parece deberse únicamente a una deficiencia de hierro porque la dieta parece tener una cantidad adecuada; probablemente esté más en relación con el exiguo contenido de proteínas animales de la ración.

  10. [Nutrition and child development II; a comparison of physical development in two school children groups with different income level (Rev Clin Esp 1944; 12:155-164) ].

    Science.gov (United States)

    Grande Covián, F; Rof Carballo, J; Jiménez García, F

    2014-09-01

    El estudio comparativo de dos grupos de niños en edad escolar y de nivel económico diferente demuestra que los que pertenecen a un suburbio madrileño económicamente pobre sufren un retraso en el crecimiento que se caracteriza por una talla y un peso inferiores en relación con la edad. El retraso del peso corporal es proporcionalmente mayor al de la talla. Cuando se calcula según WETZEL la edad que teóricamente corresponde al desarrollo corporal de estos niños se observa un retraso de 2,94 años para una edad término medio de 10,14 años. El retraso global del desarrollo somático representa por tanto el 29 por 100 de la edad cronológica media. Este retraso en el desarrollo debe atribuirse principalmente a causas dietéticas y no solo a carencias específicas, sino sobre todo a insuficiencia cuantitativa en la dieta consumida. Desde el punto de vista cualitativo es probablemente la falta de leche en la dieta uno de los más importantes factores en la génesis de este trastorno del desarrollo.

  11. Barrages de tufs calcaires et cascades dans le Centre-Var : rapport avec les eaux des sources karstiques, historique et déclin actuel

    Directory of Open Access Journals (Sweden)

    Jean Nicod

    2010-03-01

    Full Text Available Dans les vallées de l'intérieur de la Provence, de grandes accumulations de tufs et de travertins sont liées aux sources karstiques importantes. En rapport avec l'évolution géomorphologique, les travertins anciens forment des balcons et des terrasses. La période récente de grande construction travertineuse débute souvent au Préboréal et se généralise dans l'Atlantique. Au cours du Néolithique final, cette sédimentation décroît en fonction de la détérioration climatique et de la déforestation liée à la pression anthropique. Cependant quelques barrages (dômes stromatolitiques et marais, avec dépôts de tourbes, persistent jusqu'à l'âge historique. Dans le Centre-Var, les dépôts de tufs restent actifs dans quelques sites refuges, dans les hautes vallées forestières, proches des sources karstiques, et sur quelques grandes cascades. De plus, le long des rivières, des cascades à tufs sont issues des aménagements de moulins et de canaux d'irrigation.La sédimentation des tufs dépend de nombreux facteurs en interaction, dont :- la minéralisation carbonatée des eaux des sources karstiques,- le régime hydrologique saisonnier,- l'écosystème régional et local (forêts, ripisylves,- le biotope algo-bryophytique.De nos jours, la sédimentation stromatolitique est en situation critique du fait de l'impact de multiples facteurs en rapport avec l'accroissement de l'urbanisation et les changements environnementaux :- pollution, accroissement de la turbidité sur les petits affluents résultant de l'agriculture mécanisée,- diminution drastique des débits dans les saisons de printemps-été, où l'activité algo-bryophytique est la plus favorable, du fait de l'augmentation générale des prélèvements.La période de sécheresse récente (2006-2008 a accentué ces impacts sur les barrages de tufs. Et la protection de ces sites de grand intérêt environnemental et patrimonial pose des problèmes complexes.In the valleys of inner Provence, numerous travertine formations are wide extension in relation with important karstic springs. Because the geomorphological evolution, the old travertines are maked up balconies and terraces. The recent period of main travertine construction begins as far back as in the Preboreal (even in Bölling at southern Luberon and appears generalized in the Atlantic. In the late Neolithic (around 4000 BP, this sedimentation decreases with the climatic deterioration and the opening of forest cover under the weight of human pressure. However some tufa dams (stromatolite doms and associated wetland with peat deposits continues up to the historic times. In the Middle Var County, these tufa deposits on the dams remains active in some refuge sites, in the upper and woody valleys, near the karstic springs, and in any high waterfalls. More along the rivers, some waterfalls with tufa deposits proceeds from the old mills and irrigation canal fitting. This tufa sedimentation is in relation with the interference of multiple factors, whose:- carbonate mineralization of the karstic springs,- seasonal working of the hydrosystem,- regional and local ecosystem (forested land, important riparian cover,- algo-bryophitic biotope.Nowadays, the stromatolitc sedimentation is in critical situation because the impact of multiple factors in relation with increased urbanization and environmental change:- river pollution, increased turbidity in little tributaries flowed from agricultural mecanization,- decreased flow in seasonable times (spring - summer, the most favourable to the algo-bryophytic activity, because the common increasing water sample.The recent drought period (2006-2008 has maked worse these impacts on the tufa dams. And the protection of these sites of large environmental and patrimonial interest put complex problems.

  12. What Are the Recommended Timing and Screening Modalities in Women at Higher Risk for Developing Breast Cancer? A Clin-IQ

    Science.gov (United States)

    Jatala, Summer; Fitzgerald, Shawn; Tietze, Pamela; Ramakrishnan, Kalyanakrishnan; McCarthy, Laine H.; Wickersham, Elizabeth

    2016-01-01

    Early detection of breast cancer is desirable to prevent progression to advanced disease. This subject has been one of significant study and debate for women at normal risk, and recommendations continue to evolve. However, with regard to women at high risk, the recommendations from various health care professional organizations, including the recent recommendations from the United States Preventative Services Task Force, are different and also inconsistent concerning when to begin screening and which modalities should be used. We review several randomized controlled trials and consensus opinions regarding when to begin screening for breast cancer and how to best screen women at high risk. Specifically, we address women with known personal history of breast cancer, prior mantle radiation, or specific family history (including genetic family history) of breast cancer. The purpose of this inquiry is to present current evidence and suggest a clinical pathway regarding the screening of women at high risk for breast cancer. PMID:26848484

  13. What Are the Recommended Timing and Screening Modalities for Women at Higher Risk of Developing Breast Cancer? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Summer Jatala

    2015-01-01

    Full Text Available Early detection of breast cancer is desirable to prevent progression to advanced disease. This subject has been one of significant study and debate for women at normal risk, and recommendations continue to evolve. However, with regard to women at high risk, the recommendations from various health care professional organizations, including the U.S. Preventive Services Task Force, are different and also inconsistent concerning when to begin screening and which modalities should be used. We review several randomized controlled trials and consensus opinions regarding when to begin screening for breast cancer and how to best screen women at high risk. Specifically, we address women with known personal history of breast cancer, prior mantle radiation or specific family history (including genetic family history of breast cancer. The purpose of this inquiry is to present current evidence and suggest a clinical pathway regarding the screening of women at high risk for breast cancer.

  14. Association Between Organizational Citizenship Behavior and Educational Performance of Faculty Members in Tabriz University of Medical Sciences- 2014 [Res Dev Med Educ 2015;4(1:81-84

    Directory of Open Access Journals (Sweden)

    Asadullah Khadivi

    2015-12-01

    Results: There was a significant relationship between altruism and educational performance (P =0.043. There was a significant relationship between conscientiousness and educational performance (p=0.046. A significant relationship was observed between sportsmanship and educational performance (p=0.004. There was no significant relationship between civic virtue and educational performance (p=0.98. A significant relationship was observed between respect and educational performance (P>0.001. There was no relationship between citizenship behavior and gender of the faculty members (P> 0.05. Conclusion: The results of this study showed that the more faculty members have the spirit of cooperation and assistance to colleagues and students and try to understand the specific situations that students face, the more effective they are in increasing the educational performance at the university level.

  15. Fruits of Knowledge: Polemics, Humour and Moral Education in the Writings of Rokeya Sakhawat Hossain, Lila Majumdar and Nabaneeta Dev Sen

    NARCIS (Netherlands)

    Bagchi, B.

    2014-01-01

    This paper analyses literary sources, by three women writing in Bengali, from c.1900 to contemporary times. These writings offer far more complex, heterogeneous, innovative and creative strategies for the shaping, reform and moral education of subjects, than have hitherto been recognised. Authors fo

  16. Ivan Grohar and Oskar Dev – An Interdisciplinary and Multidisciplinary Fragment Comparison of Their Artistic Works in Škofja Loka/Slovenia (1905-1911)

    OpenAIRE

    Franc Križnar

    2014-01-01

    The new Grohar’s room in the Škofja Loka Mu¬seum that is located in a more than a thousand years old town, some kilometres northwest of Ljubljana, Slove¬nia, represents one of the new possibilities to popularize old local history. Ivan Grohar (1867−1911) is one of the four well-known Slovenian painters from the beginning of the 20th century, together with Rihard Jakopič, Matija Jama and Matej Sternen. These Slovenian painters are the founders of Impressionism within the modern style. Škofja L...

  17. XtraReports报表高级用法——DevExpress For VS.NET高级技巧系列(六)

    Institute of Scientific and Technical Information of China (English)

    李福红

    2012-01-01

    XtraReports是开发的新一代适用于Windows.NET和ASP.NET开发的控件.XtraReports 组件可以整合于Visual Studio IDE之中,带来更高的动作效率,同时,对于应用软件和网站报表发布它具有更大的灵活性.

  18. L'anglais lingua franca de l'Union européenne : impératif de solidarité, source d'injustice, facteur de déclin ?

    OpenAIRE

    Van Parijs, Philippe

    2006-01-01

    La construction européenne peut-elle se justifier comme un instrument efficace au service de la solidarité ? Seulement si la démocratie européenne parvient à s'épaissir. Et pour s'épaissir, celle-ci doit impérativement adopter une lingua franca unique qui se superpose, sans se substituer, aux langues nationales et régionales existantes. Mais l'adoption comme lingua franca d'une des langues de l'Union ne créet-elle pas à son tour des injustices ? Si oui, comment y remédier ? Et la diffusion mê...

  19. 亚麻籽能改善绝经妇女的血脂,但对骨代谢无作用[英]/Lncas E…∥J Clin Endocrinol Metab.

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    亚麻籽富含木脂素类,这是一类植物雌激素。由于它对人类健康有益,故已成为人类的饮食成分。据报道,植物雌激素能降低血清胆固醇水平,以及具雌激素样、抗雌激素样和抗氧化活性。鉴于木脂素类与雌激素的结构类似,以及雌激素能有效地防止绝经妇女的骨质丢失,作者用亚麻籽进行了一项随机、双盲、平行对照的临床试验,以验证亚麻籽是否有益于骨骼健康。

  20. Is 13-Valent Pneumococcal Conjugate Vaccine (PCV13) Combined With 23-Valent Pneumococcal Polysaccharide Vaccine (PPSV23) Superior to PPSV23 Alone for Reducing Incidence or Severity of Pneumonia in Older Adults? A Clin-IQ

    Science.gov (United States)

    Hayward, Starla; Thompson, Lou Ann; McEachern, Andrea

    2016-01-01

    Pneumonia infection is a significant cause of morbidity and mortality worldwide. In addition to the public health concerns, pneumonia also accounts for a significant cost to the health care system. Currently there are two leading vaccines targeted against S. pneumoniae: 23-valent pneumococcal polysaccharide vaccine (PPSV23) and 13-valent pneumococcal conjugate vaccine (PCV13). Until recently the recommendation for adult pneumonia vaccination has been a single dose of PPSV23 for all adults 65 years and older. However, concerns were raised regarding the vaccine’s efficacy due to the persistent burden of pneumococcal disease in the elderly population. This paper focuses on two trials which evaluate the safety and efficacy of PCV13 in the adult population. The first study reveals improved immune response with the addition of PCV13 to PPSV23, while the second shows PCV13 was effective in the prevention of vaccine-type community-acquired pneumonia. The two studies observed adequate safety profiles for PCV13 in series with PPSV23 and with PCV13 compared to placebo. PMID:27376105

  1. Le genre féerique illustré à l’époque victorienne : splendeurs et déclin d’un genre entré en résistance

    OpenAIRE

    Doussot, Audrey

    2015-01-01

    After having been blacklisted for decades, fairy tales unexpectedly came back into favour in Great Britain during the Victorian period, being staunchly supported by authors like Ruskin, Dickens or MacDonald. Visual arts too drew inspiration from fairy literature and lore, appropriating their themes, motifs and characters. In this context, illustrated Victorian fairy tales became vehicles of resistance against the banishment of imaginary supernatural literature and the rejection of illustratio...

  2. Correction: Grömminger, S., et al. Fetal Aneuploidy Detection by Cell-Free DNA Sequencing for Multiple Pregnancies and Quality Issues with Vanishing Twins. J. Clin. Med. 2014, 3, 679-692

    Directory of Open Access Journals (Sweden)

    Sebastian Grömminger

    2014-11-01

    Full Text Available The authors wish to make the following corrections to this paper [1]: On page 683 at the end of Section 3.2. lines 13–14, the word “no” is missing. The correct sentence should be: “There has been no evidence of false-negative NIPT results so far in the pregnancies included in this study.”[...

  3. 糖尿病酮症酸中毒并发急性肾功能衰竭20例临床分析%Diabetic ketoacidosis complicated with acute renal failure of 20 cases of clin-ical analysis

    Institute of Scientific and Technical Information of China (English)

    郭杰

    2016-01-01

    目的:对糖尿病酮症酸中毒并发急性肾功能衰竭的临床治疗效果予以探究。方法随机选取该院自2013年2月-2014年2月期间收治的糖尿病酮症酸中毒并发急性肾功能衰竭患者20例,按照患者挂号的先后顺序,将其随机均分成两组,观察组中10例患者,对照组中10例患者,其中对照组患者采用普通血液透析进行治疗,观察组患者采用连续性血液净化治疗,观察并分析两组患者的临床疗效。结果观察组患者二氧化碳结合力、肌酐、渗透压、尿素氮水平及空腹血糖显著优于对照组,观察组患者的治疗总有效率为90.0%显著高于对照组患者的60.0%,组间差异具有统计学意义,P<0.05,且组间之间的差异具有统计学研究意义。结论对糖尿病肾病酮症酸中毒合并急性肾功能衰竭患者采用连续性血液净化治疗,不仅能够有效清除患者机体内小分子毒素,而且还能够纠正电解质及酸碱代谢紊乱,获得了显著的治疗效果,对于提高患者的生存质量和预后质量具有十分重要的意义,值得大力推广和应用。%Objective Analysis of clinical therapeutic effect on diabetic ketoacidosis complicated with acute renal failure. Methods in our hospital were randomly selected 20 cases of diabetic ketoacidosis complicated with acute renal failure pa-tients, were randomly assigned to two groups, observation group (10 cases), control group (10 cases),The control group were treated with conventional hemodialysis, the observation group were treated with continuous blood purification. Results Car-bon dioxide binding force, creatinine, osmotic pressure, urea nitrogen level and fasting blood glucose in the observation group were significantly better than those in the control group, the total effective rate of the observation group was signifi-cantly higher than that in the control group 60%, and the difference between the groups was statistically significant. Con-clusion On diabetic nephropathy in type 2 diabetes mellitus ketoacidosis combined with acute renal failure patients using continuous blood purification treatment, not only can effectively remove in the body of patients with small molecule toxin, but also be able to correct electrolyte and acid-base metabolism disorder, treatment effect is very significant, for patients survival quality and prognosis of quality has very important significance, it is worth popularization and application.

  4. Is 13-Valent Pneumococcal Conjugate Vaccine (PCV13 Combined With 23-Valent Pneumococcal Polysaccharide Vaccine (PPSV23 Superior to PPSV23 Alone for Reducing Incidence or Severity of Pneumonia in Older Adults? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Starla Hayward

    2016-04-01

    Full Text Available Pneumonia infection is a significant cause of morbidity and mortality worldwide. In addition to the public health concerns, pneumonia also accounts for a significant cost to the health care system. Currently there are two leading vaccines targeted against Streptococcus pneumoniae: 23-valent pneumococcal polysaccharide vaccine (PPSV23 and 13-valent pneumococcal conjugate vaccine (PCV13. Until recently, the recommendation for adult pneumonia vaccination has been a single dose of PPSV23 for all adults aged 65 years or older. However, concerns were raised regarding the vaccine’s efficacy due to the persistent burden of pneumococcal disease in the elderly population. This paper focuses on two trials that evaluated the safety and efficacy of PCV13 in the adult population. The first study reveals improved immune response with the addition of PCV13 to PPSV23, while the second shows PCV13 was effective in the prevention of vaccine-type community-acquired pneumonia. Both studies observed adequate safety profiles for PCV13 in series with PPSV23 and with PCV13 compared to placebo.

  5. In Adult Smokers Unwilling or Unable to Quit, Does Changing From Tobacco Cigarettes to Electronic Cigarettes Decrease the Incidence of Negative Health Effects Associated With Smoking Tobacco? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Jennifer Brown

    2014-05-01

    Full Text Available Data from a randomized controlled trial and systematic review support the claim that switching from tobacco cigarettes to electronic cigarettes (e-cigarettes can reduce the short-term negative health effects of smoking. In adult smokers unwilling or unable to quit, exhaled carbon monoxide levels, total number of cigarettes smoked, and exposure to nitrosamine chemicals were reduced within a 12-month period. While the e-cigarette industry remains largely unregulated thus far, these studies provide encouraging hope in the uphill battle toward helping patients make informed and healthy choices.

  6. In adult smokers unwilling or unable to quit, does changing from tobacco cigarettes to electronic cigarettes decrease the incidence of negative health effects associated with smoking tobacco? A Clin-IQ

    Science.gov (United States)

    Brown, Jennifer; Brown, Brandon; Schwiebert, Peter; Ramakrisnan, Kalyanakrishnan; McCarthy, Laine H.

    2016-01-01

    Data from a randomized controlled trial and systematic review support the claim that switching from tobacco cigarettes to electronic cigarettes (e-cigarettes) can reduce the short-term negative health effects of smoking. In adult smokers unwilling or unable to quit, exhaled carbon monoxide levels, total number of cigarettes smoked, and exposure to nitrosamine chemicals were reduced within a 12-month period. While the electronic cigarette industry remains largely unregulated thus far, these studies provide encouraging hope in the uphill battle toward helping patients make informed and healthy choices. PMID:26855963

  7. Rebuttal to McAleer J. Mobility redux: Post-World War II prosthetics and functional aids for veterans, 1945 to 2010. J Rehabil Res Dev. 2011;48(2:vii-xvi.

    Directory of Open Access Journals (Sweden)

    Stewart M. Coulter, PhD

    2011-07-01

    Full Text Available Dear Editor:This letter addresses the following sentence in the "Mobility redux: Post-World War II prosthetics and functional aids for veterans, 1945 to 2010" editorial that appeared in JRRD, Volume 48, Number 2. The sentence on page xv, second column: "Early testing and rigorous subject feedback clearly showed that DEKA II's first active socket design was not what patients wanted or needed." is not accurate. There is evidence in the historical literature on problematic prosthetic sockets. However, user response to the interface design introduced as part of the DEKA Arm System in collaboration with prosthetists at biodesigns, Inc (Santa Monica, California and Next Step Orthotics and Prosthetics, Inc (Manchester, New Hampshire has been quite favorable.It would be accurate to say "Early testing and rigorous subject feedback clearly showed that the active socket design used as part of the DEKA Arm System offers significant benefits and was positively received by research subjects."

  8. Letters To The Editor: Rebuttal to Ottomanelli et al. Methods of a multisite randomized clinical trial of supported employment among veterans with spinal cord injury. J Rehabil Res Dev. 2009;46(7:919-30.

    Directory of Open Access Journals (Sweden)

    Marcel Dijkers, PhD

    2010-07-01

    Full Text Available Probably no fashion has gripped first medicine; then the rest of health care; and finally social services, vocational rehabilitation, education, and other professional fields as quickly and deeply as evidence-based practice (EBP. There have been claims that there is nothing new here, that professionals have always been required to base treatment of their patients/clients on evidence as to what are effective, efficient, and reliable methods of diagnosing/assessing, treating, or offering prognosis, and have done so. However, the core message of EBP has been a worthwhile one whatever one thinks of that claim: not any odd piece of evidence will do. To provide patients/clients with optimal service, one needs to base it on a systematic study of the most recent and most appropriate evidence, carefully evaluated for potential biases and errors. Probably as a result of the prominence of the originators of EBP in medicine, as well as the appealing and easy quantitative and mathematical approaches to evidence evaluation, EBP is now a bandwagon few people dare to disdain publicly. In fact, adding the label "evidence-based" to about anything and everything done professionally is seen as a way of giving it a modern, up-to-date, scientific cachet that will appeal to other professionals, if not patents/clients. EBP has become a holy cow to whom tribute is due.

  9. The development of [得 DE+V] and [V +得 DE]constructions in the Hunan dialects%湖南方言“得+V”和“V+得”结构的发展

    Institute of Scientific and Technical Information of China (English)

    伍云姬

    2001-01-01

    得DE"to obtain"is a linguistic sign which has a long history and has very complex usages.This paper will focus on the development of[DE+V]and[V+DE]constructions in which both the DE are Claimed to be used as modal auxiliaries and indicate the notion of possibilities in Chinese throughout the history.[DE+V]appeared earlier than[V+DE](Yue Junfa,1984,Yang Ping,1989,Sun Chaofen 1996,among others).Both constructions are rarely used in Mandarin but are till active in the Hunan dialects.The data in Hunan dialects show that[DE+V]and [V+DE]constructions do not only indicate possibilities,and even when the two constructions both indicate possibilities,they are not identical and not always interchangeable.In the Hunan dialects,the following contrasts between these two constructions can be found:[DE+V][V+DE] Volition Abiloty Possibility Permission Obligation Possibility In this paper,the different usages across localities in Hunan will examined, and the hypothesis of the order differences and the path of development will be stressed.This paper will concentrate on the [DE+V]and [V+DE]constructions.The focus will be on the semantic contrasts of these two constructions in which the word orders are opposite in the Hunan dialects,as well as the hypothesis of the paths of development of the two constructions.

  10. Hassas radyal hız ölçümleriyle G-türü dev yıldızların çevresinde gezegen araştırmaları

    OpenAIRE

    Yilmaz, Mesut

    2011-01-01

       Bu tez çalışmasıyla, ülkemizde yeni bir araştırma alanı olarak, uluslararası bir işbirliği çerçevesinde TÜBİTAK Ulusal Gözlemevi’nde (TUG)  ilk kez Güneş Sistemi dışı  gezegen arama çalışmaları başlatıldı. Bu amaçla bazı dikine hız standardı yıldızların ve çevrelerinde gezegen barındırdığı bilinen bazı yıldızların yanı sıra bazı hedef yıldızların da I2 (iyodin) hücresi ile yüksek çözünürlüklü tayfları elde edildi. Gözlenen...

  11. The application of low angle light scattering to evaluate qualitatively and quantitatively the dynamics of formation of oligomers in heme protein sensors

    Science.gov (United States)

    Sabino, Luis G.; Guimarães, Wellinson Gadelha; Costa, Pedro Mikael; Carepo, Marta S. P.; Gondim, Ana C. S.; Lopes, Luiz G. F.; Sousa, Eduardo H. S.

    2016-03-01

    The aim of this study is to investigate the structural organization and oligomerization properties of the sensory kinase protein DevS using low-angle light scattering (LALS) and gel filtration chromatography (HPLC). In addition, the structural characteristics of FixL and BSA were investigated and compared with DevS to better elucidate LALS technique. DevS is a direct and specific O2 sensing protein in Mycobacterium tuberculosis and acts as an activator of the transcription factor protein DevR. This latter triggers the latency state of tuberculosis under hypoxic conditions. DevS has been briefly evaluated under different conditions of concentration, ionic strength and temperature. LALS and gel filtration (HPLC) analysis were performed right after DevS purification process. The results of LALS for BSA proved to be highly reliable with a Rh value of c.a. 3.7 nm. Considering BSA a globular protein, the molecular weight estimative, using LALS was near 67 KDa, which is reasonably within the value reported in the literature. Preliminary LALS results showed a hydrodynamic radius (Rh) varying from 4.2-15.0 nm for DevS protein, and an average of 6.7 nm. These data supported, along with gel filtration, a dimer (~130 KDa) and tetramer (255 KDa) as the main DevS species. Additionally, it was found higher oligomeric species by gel filtration suggesting either an equilibrium of oligomers or an aggregation process that deserves further studies.

  12. L’essor et le déclin de la stratégie économique keynésienne – structuraliste au Mexique Rise and demise of the Structuralist-Keynesian economic strategy in Mexico La expansión y la declinación de la estrategia económica keynesiana-estructuralista en México

    Directory of Open Access Journals (Sweden)

    Julio López G.

    2012-04-01

    Full Text Available Pendant au moins deux décennies après la seconde guerre mondiale, la croissance économique au Mexique a été très rapide, à tel point que pour la caractériser, le terme « miracle mexicain » a été introduit. Le but de ce travail est d’étudier les causes immédiates ainsi que les origines historiques de l’essoufflement du miracle mexicain. L’auteur examine les limites de la stratégie fondée sur la substitution des importations en prenant en compte aussi bien des problèmes du côté de l’offre que de la demande. Il étudie aussi la relation entre économie et politique durant le « miracle », en mettant l’accent sur les accords et les conflits au sein des classes dominantes. Il montre comment les limites de l’offre et de la demande ont fait plus difficile de maintenir un taux de croissance élevé surtout après que le développement de l’économie mondiale s’est ralenti, à un moment où la substitution des importations avait atteint un niveau relativement avancé. Il avance l’hypothèse que le ralentissement de la croissance a aussi mis en danger l’accord implicite entre la haute bureaucratie d’état et les classes dominantes.The aim of this paper is to study the proximate causes as well as the historical origins of the downfall of the Mexican “economic miracle”, which took place approximately between 1950 and the mid-1970s. The author shares a view that holds that in the mid-1970s, Mexico’s previous growth strategy faded, and that sees the economic troubles as an expression of the exhaustion of that strategy. He shows how this economic exhaustion came about by considering the supply and demands limits to fast growth in an international context that deteriorated, especially when the import substitution strategy reached a relatively advanced stage. He then considers the relationship between economics and politics during the “miracle” period as much as in the following years, arguing that fast and stable growth also served as material support for an alliance between the upper classes and the political bureaucracy. Thus, the demise of the previous economic model also eroded the material and ideological framework that made possible or eased the class alliance built during the “miracle” years.Durante al menos dos décadas posteriores a la Segunda Guerra Mundial, el crecimiento de México fue muy rápido, hasta el punto de que para caracterizarlo se habló del « milagro mexicano ». El objetivo de este trabajo es el de estudiar las causas inmediatas así como los orígenes históricos del agotamiento del milagro mexicano. El autor examina los limites de la estrategia fundada en la sustitución de importaciones tomando en cuenta tanto los problemas del lado de la oferta como de la demanda. Estudia también la relación entre economía y política durante la vigencia del « milagro » poniendo el acento sobre los acuerdos y los conflictos en el seno de las clases dominantes. Muestra cómo los limites de la oferta y la demanda han hecho muy difícil mantener las tasas de crecimiento elevadas sobre todo después que se frenó el desarrollo de la economía mundial, en el momento en que la sustitución de importaciones había alcanzado un nivel relativamente elevado.

  13. L’essor et le déclin de la stratégie économique keynésienne – structuraliste au Mexique Rise and demise of the Structuralist-Keynesian economic strategy in Mexico La expansión y la declinación de la estrategia económica keynesiana-estructuralista en México

    OpenAIRE

    Julio López G.

    2012-01-01

    Pendant au moins deux décennies après la seconde guerre mondiale, la croissance économique au Mexique a été très rapide, à tel point que pour la caractériser, le terme « miracle mexicain » a été introduit. Le but de ce travail est d’étudier les causes immédiates ainsi que les origines historiques de l’essoufflement du miracle mexicain. L’auteur examine les limites de la stratégie fondée sur la substitution des importations en prenant en compte aussi bien des problèmes du côté de l’offre que d...

  14. Introduction : L’évolution des réseaux de chemins de fer d’intérêt local et des tramways voyageurs-marchandises de leur naissance à leur déclin, 1865-1951

    OpenAIRE

    Wolkowitsch, Maurice

    2015-01-01

    Ce colloque est consacré aux chemins de fer d’intérêt local et tramways voyageurs et marchandises définis par les lois de 1865, 1880 et 1913 ; ces réseaux partagent avec les lignes secondaires des grandes compagnies une même fonction de désenclavement des campagnes, mais ils méritent une étude spécifique. Ces réseaux secondaires dépassent 20 000 km en 1927, soit la moitié du réseau d’intérêt général ; ils emploient 26 000 cheminots, utilisent 1 500 locomotives et automotrices, 5 000 voitures,...

  15. DMPD: CSF-1 and cell cycle control in macrophages. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 8981359 CSF-1 and cell cycle control in macrophages. Hamilton JA. Mol Reprod Dev. 1...D 8981359 Title CSF-1 and cell cycle control in macrophages. Authors Hamilton JA. Publication Mol Reprod Dev

  16. A mapping study on cooperation between information system development and operations

    NARCIS (Netherlands)

    Erich, Floris; Amrit, Chintan; Daneva, Maya; Jedlitschka, Andreas; Kuvaja, Pasi; Kuhrmann, Marco; Männistö, Tomi; Münch, Jürgen; Raatikainen, Mikko

    2014-01-01

    DevOps is a conceptual framework for reintegrating development and operations of Information Systems.We performed a Systematic Mapping Study to explore DevOps. 26 articles out of 139 were selected, studied and summarized. Based on this a concept table was constructed. We discovered that DevOps has n

  17. West Syndrome in South Iran: Electro-Clinical Manifestations

    Directory of Open Access Journals (Sweden)

    ALI Akabar ASADI-POOYA

    2013-08-01

    . Infantile spasms: West syndrome. Arch Neurol. 2002 Feb;59(2:317-8.3. Hrachovy RA. West’s syndrome (infantile spasms.Clinical description and diagnosis. Adv Exp Med Biol.2002;497:33-50. Review.4. Riikonen R, Donner M. Incidence and aetiology of infantile spasms from 1960 to 1976: a population study in Finland. Dev Med Child Neurol. 1979 Jun;21(3:333-43.5. Dulac O. What is West syndrome? Brain Dev. 2001 Nov;23(7:447-52. Review. 6. Wong V. West syndrome-The University of Hong Kong experience (1970-2000. Brain Dev. 2001 Nov;23(7:609-15.7. Kalra V, Gulati S, Pandey RM, Menon S. West syndrome and other infantile epileptic encephalopathies -Indian hospital experience. Brain Dev. 2001 Nov; 23(7:593-602. Corrected and republished in: Brain Dev. 2002 Mar;24(2:130-9.8. Young C; Taiwan Child Neurology Society. National survey of West syndrome in Taiwan. Brain Dev. 2001 Nov;23(7:570-4.9. Asadi-Pooya AA, Mintzer S, Sperling MR. Nutritional supplements, foods, and epilepsy: is there a relationship?Epilepsia. 2008 Nov;49(11:1819-27.10. Mikati MA, Trevathan E, Krishnamoorthy KS, Lombroso CT. Pyridoxine - dependent epilepsy: EEG investigations and long-term follow-up. Electroencephalogr Clin Neurophysiol. 1991 Mar;78(3:215-21.11. Nabbout R, Soufflet C, Plouin P, Dulac O. Pyridoxine dependent epilepsy: a suggestive electroclinical pattern. Arch Dis Child Fetal Neonatal Ed. 1999 Sep;81(2:F125-9.12. Gospe SM Jr. Pyridoxine-dependent seizures: new genetic and biochemical clues to help with diagnosis and treatment. Curr Opin Neurol. 2006 Apr;19(2:148-53. Review.13.Riikonen R. The latest on infantile spasms. Curr Opin Neurol. 2005 Apr;18(2:91-5. Review.

  18. Asociaciones palinológicas en las formaciones Los Monos (Devónico) e Itacua (Carbonífero Inferior) en Balapuca (Cuenca Tarija), sur de Bolivia: Parte 1. Formación Los Monos Palynological assemblages present in Los Monos (Devonian) and Itacua (Lower Carboniferous) formations at Balapuca (Tarija basin), southern Bolivia: Part One. Los Monos Formation

    OpenAIRE

    Mercedes di Pasquo

    2007-01-01

    Se caracterizan cuali-cuantitativamente dos asociaciones palinológicas recuperadas de ocho muestras fértiles de la Formación Los Monos (Eifeliano tardío-Frasniano temprano), expuesta en la localidad de Balapuca, ubicada en la margen boliviana del río Bermejo en la sierra de San Telmo. Esta unidad depositada en la Cuenca Tarija, sobreyace a la Formación Pescado (o Huamampampa, Emsiano-Eifeliano), y subyace, cuando está preservada, a la Formación Iquirí (Frasniano-Famenniano). La sección litoló...

  19. Neuroimaging in Cerebral Palsy – Report from North India

    Directory of Open Access Journals (Sweden)

    Anju AGGARWAL

    2013-11-01

    ;109:8-14.http://www.newbornwhocc.org/pdf/database.pdfRikomen R, Raumanvrita S, Sinivuori E, Seppala T. Changing pattern of cerebral palsy in southwest region of Finland. Acta Pediatr Scand 1989; 78(4:581-7.Pharaoh POD, Plat MJ, Cooke T. The changing epidemiology of cerebral palsy. Arch Dis Child 1996;75(3: F169-73.Eischer PS, Batshaw M. Cerebral Palsy. Ped Clin North Am 1993;40(3:537-51.Bax M, Tydeman BA, Flodmark O. Clininical and MRI correlates of cerebral palsy: the European Cerebral PalsyStudy. JAMA 2006; 296(13:1602-08.Korzeniewski SJ, Birbeck G, DeLano MC, Potchen MJ, Paneth N. A systematic review of neuroimaging for cerebral palsy. Journal of Child Neurology 2008;23(2:216-27.Robinson MN, Peake LJ, Ditchfield MR, Reid SM. Magnetic Resonance imaging findings in population based cohort of children with cerebral palsy Dev Med Child Neurol 2009; 51(1:39-45.Shevell M, Ashwal S, Donley D, Flint J, Gingold M, Hirtz D, et al. Practice parameter: Evaluation of the child with global developmental delay: Report of the Quality Standards Subcommittee of the American Academy of Neurology and The Practice Committee of the Child Neurology Society. Neurology 2003; 60(3; 367-80.Ashwal S, Russman BS, Blasco PA, Miller G, Sandler A, Shevell M, et al. Practice parameter: diagnostic assessment of the child with cerebralpalsy: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology 2004; 23;62(6: 851-63. 

  20. Associations between Manual Abilities, Gross Motor Function, Epilepsy, and Mental Capacity in Children with Cerebral Palsy

    Directory of Open Access Journals (Sweden)

    Ewa GAJEWSKA*

    2014-04-01

    2013;111:183-95.Sellier E, Uldall P, Calado E, Sigurdardottir S, Torrioli MG, Platt MJ, et al. Epilepsy and cerebral palsy: characteristics and trends in children born in 1976-1998. Eur J Paediatr Neurol 2012;16(1:48-55.Wallace SJ. Epilepsy in cerebral palsy. Dev Med Child Neurology 2001;43(10:713-7.Bax MCO. Cerebral palsy. In: Aicardi J, editor. Disease of the nervous system in childhood. 2nd ed. London: Mc Keith Press; 1998. p. 210-39.Reid A, Imrie H, Brouwer E, Clutton S, Evans J, Russell D, et al. “If I knew then what I know now”: parents’ reflections on raising a child with cerebral palsy. Phys Occup Ther Pediatr 2011;31(2:169-83.Rosenbaum P, Paneth N, Leviton A, Goldstein M, Bax M, Damiano D, et al. A report: the definition and classification of cerebral palsy April 2006. Dev Med Child Neurology 2007;109:8-14.Palisano R, Rosenbaum P, Bartlett D, Livingston M. Content validity of the expanded and revised Gross Motor Function Classification System. Dev Med Child Neurology 2008;50(10:744-50.Öhrvall AM, Eliasson AC. Parents and therapists perceptions about the content and construct of Manual Ability Classification System, MACS. Scand J Occup Ther 2010;17(3:209-16.Marszał E.Występowanie, diagnostyka i leczenie padaczki u dzieci z mózgowym porażeniem dziecięcym. Neurologia dziecięca;2006:15, 30:65-8.Blair E, Watson L. Epidemiology of cerebral palsy. Semin Fetal Neonatal Medicine 2006;11(2:117-25.Meberg A, Broch H. Etiology of cerebral palsy. J Perinat Med 2004;32(5:434-9.Blair E. Epidemiology of the cerebral palsies. Orthop Clin North Am 2010;41(4:441-55.Hellbrűge T, Fritz L, Menara D, Schamberger R, Rautenstrauch T. Monachijska Funkcjonalna Diagnostyka Rozwojowa. Kraków: Antykwa; 1994. p. 80-130.Arnould C, Penta M, Renders A, Thonnard JL. Abilhand-Kids: a measure of manual ability in children with cerebral palsy. Neurology 2004;63(6:1045-52.Carnahan KD, Arner M, Hägglund G. Association between gross motor function (GMFCS and manual ability (MACS in

  1. A "Research" into International Student-Related Research: (Re)visualising Our Stand?

    Science.gov (United States)

    Abdullah, Doria; Abd Aziz, Mohd Ismail; Mohd Ibrahim, Abdul Latiff

    2014-01-01

    This paper uses Tight ("High Educ Res Dev" 23(4):395-411, 2004; "High Educ Res Dev" 31(5):723-740, 2012; "High Educ Res Dev" 32(1):136-151, 2013)'s journal analysis and review framework to review a sample of 497 journal articles on researches concerning international students over the past 30 years. It was found…

  2. Strategy for increasing marine fish production in Goa

    Digital Repository Service at National Institute of Oceanography (India)

    Parulekar, A.H.

    stream_size 5 stream_content_type text/plain stream_name Proc_Workshop_Evol_Strat_Dev_Agric_Anim_Husb_Fish_Goa_1991_73.pdf.txt stream_source_info Proc_Workshop_Evol_Strat_Dev_Agric_Anim_Husb_Fish_Goa_1991_73.pdf.txt Content...

  3. NCBI nr-aa BLAST: CBRC-PABE-24-0031 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-PABE-24-0031 ref|YP_001276205.1| CRISPR-associated autoregulator, DevR family ...[Roseiflexus sp. RS-1] gb|ABQ90255.1| CRISPR-associated autoregulator, DevR family [Roseiflexus sp. RS-1] YP_001276205.1 5.9 32% ...

  4. Estimation of wave forces on a tethered spherical float using potential flow theory

    Digital Repository Service at National Institute of Oceanography (India)

    Vethamony, P.; Chandramohan, P.; Sastry, J.S.

    stream_size 9 stream_content_type text/plain stream_name Proc_Int_Conf_Coast_Port_Eng_Dev_Countries_1991_1442.pdf.txt stream_source_info Proc_Int_Conf_Coast_Port_Eng_Dev_Countries_1991_1442.pdf.txt Content-Encoding ISO-8859...

  5. 40 CFR Table F-3 to Subpart F of... - Critical Parameters of Idealized Ambient Particle Size Distributions

    Science.gov (United States)

    2010-07-01

    ... Ambient Particle Size Distributions F Table F-3 to Subpart F of Part 53 Protection of Environment... Ambient Particle Size Distributions Idealized Distribution Fine Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) Coarse Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) PM2.5/PM10 Ratio FRM...

  6. Brief Report: Insistence on Sameness, Anxiety, and Social Motivation in Children with Autism Spectrum Disorder

    Science.gov (United States)

    Factor, Reina S.; Condy, Emma E.; Farley, Julee P.; Scarpa, Angela

    2016-01-01

    While the function of restricted repetitive behaviors (RRBs) in autism spectrum disorder (ASD) is unclear, RRBs may function as anxiety reduction strategies (Joosten et al. "J Autism Dev Disord" 39(3):521-531, 2009. Moreover, anxiety in ASD is associated with low social motivation (Swain et al. "J Autism Dev Disord," 2015. The…

  7. Characterization of nucleocytoplasmic shuttling and intracellular localization signals in Duck Enteritis Virus UL54.

    Science.gov (United States)

    Liu, Chaoyue; Cheng, Anchun; Wang, Mingshu; Chen, Shun; Jia, Renyong; Zhu, Dekang; Liu, Mafeng; Sun, Kunfeng; Yang, Qiao; Chen, Xiaoyue

    2016-08-01

    Duck Enteritis virus (DEV) UL54 is a homolog of herpes simplex virus-1 (HSV-1) trafficking protein ICP27, which plays an essential role in infection. In this study, DEV UL54 shuttling between the nucleus and cytoplasm was verified with a heterokaryon assay. One predicted nuclear export sequence (NES) (339-348 aa) was shown to be functional and chromosomal region maintenance 1 (CRM1)-dependent; however, the insensitivity of UL54 to Leptomycin B (LMB) and NES mutation suggests that other mechanisms are responsible for the observed nuclear export. Next, three non-classical nuclear localization sequences (NLSs), referred to as NLS1 (105-122 aa), NLS2 (169-192 aa) and NLS3 (257-274 aa), were identified. Furthermore, a recombinant DEV with the UL54 NLSs deleted (DEV- UL54 mNLSs) was constructed and showed that UL54 NLSs moderately affected DEV growth.

  8. The Best Time for EEG Recording in Febrile Seizure

    Directory of Open Access Journals (Sweden)

    Parvaneh KARIMZADEH

    2014-01-01

    seizures. Arch Pediatr Adolesc Med 1997;151(4:371-8.Nelson KB, Ellenberg JH. Predictors of epilepsy in children who have experienced febrile seizures. N Engl J Med 1976;295(19:1029-33.Anonymous. Practice parameter: the neurodiagnostic evaluation of the child with a first simple febrile seizure. American Academy of Pediatrics. Provisional Committee on Quality Improvement, Subcommittee on Febrile Seizures. Pediatrics 1996;97(5:769-72; discussion:773-5.Rosman NP. Evaluation of the child who convulses with fever. Paediatr Drugs 2003;5(7:457-61.Kanemura H, Mizorogi S, Aoyagi K, Sugita K, Aihara M. EEG characteristics predict subsequent epilepsy in children with febrile seizure. Brain Dev 2012;34(4:302-7.Yamatogi Y, Ohtahara S. EEG in febrile convulsions. Am J EEG Techno1 1990;30:267-80.Aicardi J, Chevrie JJ. The significance of electroencephalographic paroxysms in children less than 3 years of age. Epilepsia 1973;14(1:47-55.Tsuboi T. Seizures of childhood: a population-based and clinic based study. Acta Neurol Scand Suppl 1986;110:1-237.Maytal J, Steele R, Eviatar L, Novak G. The value of early postictal EEG in children with complex febrile seizures. Epilepsia 2000;41(2:219-21.Joshi C, Wawrykow T, Patrick J, Prasad A. Do clinical variables predict an abnormal EEG in patients with complex febrile seizures? Seizure 2005;14(6:429-34.Lennox-Buchthal M. Febrile convulsions: a reappraisal. Electroencephalogr Clin Neurophysiol 1973;32:Suppl:1-138.Frantzen E, Lennox-Buchtal MA, Nygraad A. Longitudinal EEG and clinical study of children with febrile convulsions. Electroencephalogr Clin Neurophysiol 1968;24(3:197-212.Kajitani T, Ueoka K, Nakamura M, Kumanomidou Y. Febrile convulsions and rolandic discharges. Brain Dev 1981;3(4:351-9.Sofijanov N, Emoto S, Kuturec M, Dukovski M, Duma F, Ellenberg JH, et al. Febrile seizures: clinical characteristics and initial EEG. Epilepsia 1992;33(1:52-7.

  9. Protective effects of recombinant glycoprotein D based prime boost approach against duck enteritis virus in mice model.

    Science.gov (United States)

    Aravind, S; Kamble, Nitin Machindra; Gaikwad, Satish S; Shukla, Sanjeev Kumar; Saravanan, R; Dey, Sohini; Mohan, C Madhan

    2015-11-01

    Duck virus enteritis, also known as duck plague, is an acute herpes viral infection of ducks caused by duck enteritis virus (DEV). The method of repeated immunization with a live attenuated vaccine has been used for the prevention and control of duck enteritis virus (DEV). However, the incidence of the disease in vaccinated flocks and latency reactivation are the major constraints in the present vaccination programme. The immunogenicity and protective efficacy afforded by intramuscular inoculation of plasmid DNA encoding DEV glycoprotein D (pCDNA-gD) followed by DEV gD expressed in Saccharomyces cerevisia (rgD) was assessed in a murine model. Compared with mice inoculated with DNA (pCDNA-gD) or protein (rgD) only, mice inoculated with the combination of gD DNA and protein had enhanced ELISA antibody titers to DEV and had accelerated clearance of virus following challenge infection. Furthermore, the highest levels of lymphocyte proliferation response, IL-4, IL-12 and IFN-γ production were induced following priming with the DNA vaccine and boosting with the rgD protein. For instance, the specially designed recombinant DEV vector vaccine would be the best choice to use in ducks. It offers an excellent solution to the low vaccination coverage rate in ducks. We expect that the application of this novel vaccine in the near future will greatly decrease the virus load in the environment and reduce outbreaks of DEV in ducks.

  10. Using HexSim to link demography and genetics in animal and plant simulations

    Science.gov (United States)

    Simulation models are essential for understanding the effects of land management practices and environmental drivers, including landscape change, shape population genetic structure and persistence probabilities. The emerging field of eco-evolutionary modeling is beginning to dev...

  11. Lipotoxicity and the role of maternal nutrition

    NARCIS (Netherlands)

    Pruis, M. G. M.; van Ewijk, P. A.; Schrauwen-Hinderling, V. B.; Ploesch, T.

    2014-01-01

    Intrauterine malnutrition predisposes the offspring towards the development of type 2 diabetes and cardiovascular disease. To explain this association, the Developmental Origins of Health and Disease hypothesis was introduced, meaning that subtle environmental changes during embryonic and foetal dev

  12. Hyperspectral remote sensing of tropical grass quality and quantity

    NARCIS (Netherlands)

    Mutanga, O.

    2004-01-01

    Resource distribution is a fundamental factor governing the movement and distribution of herbivores. Specifically, the quality (foliar concentration of nitrogen, phosphorous, calcium, magnesium, potassium and sodium) and quantity (biomass) of vegetation are important factors. In this regard, the dev

  13. Multimerization Improves Targeting of Peptide Radio-Pharmaceuticals

    NARCIS (Netherlands)

    Carlucci, Giuseppe; Ananias, Hildo J. K.; Yu, Zilin; Van de Wiele, Christophe; Dierckx, Rudi A.; de Jong, Igle J.; Elsinga, Philip H.

    2012-01-01

    Multimerization offers unique kinetic and thermodynamic properties to molecules. Multimeric ligands, characterized by multiple similar or different monomeric molecules tethered together, can bind several receptors simultaneously. Multimerization occurs also in nature. This process can be used to dev

  14. Monitor

    Data.gov (United States)

    US Agency for International Development — A custom-built, dual-language (English and Spanish) system (http://www.monitor.net.co/) developed by DevTech that debuted in January 2011. It features a central PMP...

  15. The Land Administration Domain Model

    NARCIS (Netherlands)

    Lemmen, C.; Van Oosterom, P.J.M.; Bennett, R.

    2015-01-01

    Societal drivers including poverty eradication, gender equality, indigenous recognition, adequate housing, sustainable agriculture, food security, climate change response, and good governance, influence contemporary land administration design. Equally, the opportunities provided by technological dev

  16. Bioinformatics Analysis of the Duck Enteritis Virus UL54 Gene

    Directory of Open Access Journals (Sweden)

    Chaoyue Liu

    2014-04-01

    Full Text Available In this study, we analyze the Duck Enteritis Virus (DEV UL54 gene, which has been isolated and identified in our lab (GenBank accession NO EU071033, to help deeply research on DEV. DNA sequence analysis showed that the identified ORF which composed of 1377 bp nucleotides encoded 458 amino acids with a predicted Mr. of 51.75 kDa. Multiple sequence alignment suggested that the UL54 gene was highly conserved in Alphaherpesvirinae and was similar to the other herpesviral UL54 gene. Phylogenetic analysis of the DEV UL54 gene revealed that DEV had a close evolutionary relationship with Gallid, Herpesvirus 2 (GaHV-2, Gallid Herpesvirus 3 (GaHV-3, Meleagrid Herpesvirus1 (MeHV-1 and should belong to a single cluster within the Alphaherpesvirinae subfamily.

  17. Experiment list: SRX1206064 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DMEM 10% FCS,+ hygromycin + blasticidin + doxycycline + a-amanitin || antibody=rabbit anti pan CTD (Schroe...der eta l Genes Dev. 14:2435, 2000) http://dbarchive.biosciencedbc.jp/kyushu-u/hg19

  18. Annular Hybrid Rocket Motor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Engineers at SpaceDev have conducted a preliminary design and analysis of a proprietary annular design concept for a hybrid motor. A U.S. Patent application has...

  19. Genetics Home Reference: familial glucocorticoid deficiency

    Science.gov (United States)

    ... Clark AJ, Metherell LA. ACTH resistance: genes and mechanisms. Endocr Dev. 2013;24:57-66. doi: 10. ... Metherell LA. Familial glucocorticoid deficiency: New genes and mechanisms. Mol Cell Endocrinol. 2013 May 22;371(1- ...

  20. Genomic regulatory landscapes and chromosomal rearrangements

    DEFF Research Database (Denmark)

    Ladegaard, Elisabete L Engenheiro

    2008-01-01

    The main objectives of the PhD study are to identify and characterise chromosomal rearrangements within evolutionarily conserved regulatory landscapes around genes involved in the regulation of transcription and/or development (trans-dev genes). A frequent feature of trans-dev genes...... the complex spatio-temporal expression of the associated trans-dev gene. Rare chromosomal breakpoints that disrupt the integrity of these regulatory landscapes may be used as a tool, not only to make genotype-phenotype associations, but also to link the associated phenotype with the position and tissue...... specificity of the individual CNEs. In this PhD study I have studied several chromosomal rearrangements with breakpoints in the vicinity of trans-dev genes. This included chromosomal rearrangements compatible with known phenotype-genotype associations (Rieger syndrome-PITX2, Mowat-Wilson syndrome-ZEB2...

  1. Letters to the Editor

    OpenAIRE

    Brian C. Lund, PharmD, MS; Thad E. Abrams, MD, MS

    2011-01-01

    Rebuttal to Gravely et al. Validity of PTSD diagnoses in VA administrative data: Comparison of VA administrative PTSD diagnoses to self-reported PTSD Checklist scores. J Rehabil Res Dev. 2011; 48(1):21–30.

  2. Characterization of codon usage bias in the dUTPase gene of duck enteritis virus

    Institute of Scientific and Technical Information of China (English)

    Lichan Zhao; Anchun Cheng; Mingshu Wang; Guiping Yuan; Mingsheng Cai

    2008-01-01

    A comparative analysis of the codon usage bias in the newly discovered dUTPase gene(Assigned Accession No.:DQ4861491 of the duck enteritis virus(DEV)and the dUTPase gene of 32 reference herpesviruses was performed.The results indicated that the DEV dUT-Pase gene encodes a protein of 477 amino acids,which includes five conserved motifs with a 3-1-2-4-5 arrangement.The codon adap-tation index(CAI),effective number of codons(ENC),and GC3s values indicated synonymous codon usage bias in the dUTPase gene of herpesviruses,and this synonymous bias was correlated with host evolution.The codon usage pattens of the DEV dUTPase gene were phylogenetically conserved and similar to that of the dUTPase genes of the avian alphaherpesvirus.Although codon usage in each micro-orgamsm was different,there were no strain-specific differences among them.Sixty-one codons in the predicted polypeptide.with a strong bias towards A and T at the third codon position,were used.Comparison of the codon usage in the dUTPase gene of different organisms revealed that there were 19 codons showing distinct codon usage differences between the DEV and Escherichia coli dUTPase genes;16 between the DEV and yeast dUTPase genes;and 15 between the DEV and human dUTPase genes.Analysis of variance(ANOVA) showed significant differences between the DEV and yeast dUTPase genes(r=0.536,P<0.01).The extent of codon usage bias in the DEV dUTPase gene was highly correlated with the gene expression level,therefore the results may provide usefu information for gene classification and functional studies.

  3. Activity in PythonPDEVS

    OpenAIRE

    Van Tendeloo Yentl; Vangheluwe Hans

    2014-01-01

    We introduce an activity-enhanced version of PythonPDEVS, a Parallel DEVS simulator. PythonPDEVS supports both sequential and distributed simulation. Both sequential and distributed variants of PythonPDEVS exploit information about computational activity to reduce simulation time. DEVS models can be augmented by the user with domain-specific information about computational load. This information is used by the simulator to improve performance.

  4. A Comparison of Risperidone and Buspirone for Treatment of Behavior Disorders in Children with Phenylketonuria

    Directory of Open Access Journals (Sweden)

    Afshin FAYYAZI

    2014-12-01

    and Lang W .Neurobehavioral Problems Associated with Phenylketonuria. Psychiatry (Edgemont 2009; 7(12:29–32.Luciana M, Hanson K L,Whitley C B.A preliminary report on dopamine system reactivity in PKU: acute effects of haloperidol on neuropsychological, physiological, and neuroendocrine functions. Psychopharmacology 2004;175: 18–25.Pappadopulos E, Woolston S, Chait A, Perkins M, Connor DF, Jensen P S. Pharmacotherapy of Aggression in Children and Adolescents: Efficacy and Effect Size. J CDN ACAD Child Adolesc Psychiatry 2006; 15(1:27-39.Shea S, Turgay A, Carroll A, Schulz M, Orlik H ,Smith I and et al. Risperidone in the Treatment of Disruptive Behavioral Symptoms in Children With Autistic and Other Pervasive Developmental Disorders. Pediatrcs 2004; 114:634-641.Miral S, Gencer O, Inal-Emiroglu F.N, Baykara B, Baykara A, Dirik E. Risperidone versus haloperidol in children and adolescents with AD: a randomized, controlled, doubleblind trial. Eur Child Adolesc Psychiatry 2008; 17:1–8.Aman M.G, Hollway J.A, McDougle C.J, Scahill L, Tierney E, McCracken J.T and et al. Cognitive effects of risperidone in children with autism and irritable behavior. J. Child Adolesc. Psychopharmacol 2008; 18:227–236.Pandina G.J, Bossie C.A, Youssef E, Zhu Y, Dunbar F. Risperidone improves behavioral symptoms in children with autism in a randomized, double-blind, placebocontrolled trial. J Autism Dev Disord 2007; 37:367–373.Luby J, Mrakotsky C, Stalets M.M, Belden A, Heffelfinger A, Williams M and et al. Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy. J. Child Adolesc. Psychopharmacol 2006; 16:575–587.Nagaraj R, Singhi P, Malhi P. Risperidone in children with autism: randomized, placebo controlled, double blind study. J. Child Neurol 2006; 21:450–455.Haas M, Karcher K, Pandina GJ. Treating Disruptive Behavior Disorders with Risperidone: A 1-Year, Open-Label Safety Study in Children and Adolescents. Journal of Child and

  5. In silico discovery of the dormancy regulons in a number of Actinobacteria genomes

    Energy Technology Data Exchange (ETDEWEB)

    Gerasimova, Anna; Dubchak, Inna; Arkin, Adam; Gelfand, Mikhail

    2010-11-16

    Mycobacterium tuberculosis is a dangerous Actinobacteria infecting nearly one third of the human population. It becomes dormant and phenotypically drug resistant in response to stresses. An important feature of the M. tuberculosis pathogenesis is the prevalence of latent infection without disease, making understanding of the mechanisms used by the bacteria to exist in this state and to switch to metabolically active infectious form a vital problem to consider. M. tuberculosis dormancy is regulated by the three-component regulatory system of two kinases (DosT and DevS) and transcriprional regulator (DevR). DevR activates transcription of a set of genes, which allow the bacteria to survive long periods of anaerobiosis, and may be important for long-term survival within the host during latent infection. The DevR-regulon is studied experimentally in M. tuberculosis and few other phylogenetically close Mycobacteria spp. As many other two-component systems, the devRS operon is autoregulated. However, the mechanism of the dormancy is not completely clear even for these bacteria and there is no data describing the dormancy regulons in other species.

  6. Generic Abstraction of Hardware Control Based on the ALMA Common Software

    Science.gov (United States)

    Jeram, B.; Chiozzi, G.; Ibsen, J.; Cirami, R.; Pokorny, M.; Muders, D.; Wischolek, D.

    2004-07-01

    The ALMA Common Software (ACS) is a CORBA-based framework that provides a common and homogeneous infrastructure for the whole ALMA software, from high-level data flow applications down to instrument control (Schwarz et al., 2004). This paper focuses on ACS support for the development of Control System applications. In this domain, ACS provides a generic abstraction of hardware control and monitor points that is independent of the software underneath. This abstraction layer is coupled to the hardware using the DevIO (Device Input/Output) interface, based on the Bridge design pattern. Application developers have to implement DevIO classes that handle the details of the communication with the hardware. ACS itself provides a default DevIO implementation which simply writes and reads into/from a memory location. Currently there are two other major DevIO implementations available: a CAN bus communication, used by ALMA, and a socket based implementation used by the Atacama Pathfinder EXperiment (APEX) project. In spite of using different hardware and control electronics, the DevIO abstraction allows the ALMA and APEX projects to have the same device architecture down to the level of the DevIO implementation.

  7. Autism Spectrum Disorders in Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Reza MOHAMMADI

    2011-12-01

    2007; 28: 235-258.Zaroff CM, Uhm SY. Prevalence of autism spectrum disorders and influence of country of measurement and ethnicity. Soc Psychiatry Psychiatr Epidemiol 2011;published online.Baron-Cohen S, Scott FJ, Allison C, Williams J, Bolton P, Matthews FE, et al. Prevalence of autism-spectrum conditions: UK school-based population study. Br J Psychiatry 2009;194:500-509.Brugha TS, McManus S, Bankart J, Scott F, Purdon S, SmithJ, et al. Epidemiology of autism spectrum disorders inadults in the community in England. Arch Gen Psychiatry 2011; 68: 459-465.Prevalence of autism spectrum disorders - Autism and Developmental Disabilities Monitoring Network, United States, 2006. MMWR Surveill Summ 2009; 58: 1-20.Fombonne E. Epidemiology of pervasive developmental disorders. Pediatr Res 2009; 65: 591-598.Ehlers S, Gillberg C. The epidemiology of Asperger syndrome. A total population study. J Child Psychol Psychiatry 1993; 34: 1327-1350.Kadesjo B, Gillberg C, Hagberg B. Brief report: autismand Asperger syndrome in seven-year-old children: a totalpopulation study. J Autism Dev Disord 1999; 29: 327-331.Williams JG, Higgins JP, Brayne CE. Systematic reviewof prevalence studies of autism spectrum disorders. ArchDis Child 2006; 91: 8-15.Bernier R, Mao A, Yen J. Psychopathology, families, andculture: autism. Child Adolesc Psychiatr Clin N Am 2010;19: 855-867.Shamsi-pour M, Yonesian M, Mansouri A. Epidemiologyof autism: recent challenges in prevalence of autism andits risk factors. Journal of health and knowledge 2010; 5:133.Ghanizadeh A. A preliminary study on screening prevalence of pervasive developmental disorder in school children in Iran. J Autism Dev Disord 2008; 38:759-763.Nejatisafa AA, Kazemi MR, Alaghebandrad J. Autisticfeatures in adult population: evidence for continuity ofautistic symptoms with normality. Advanced in cognitivescience 2003; 5: 34-39.Khoushabi K, Pouretemad HR. Prevalence of pervasive developmental disorders according to gender in a sampleof Iranian

  8. Expression and characterization of UL16 gene from duck enteritis virus

    Directory of Open Access Journals (Sweden)

    Wang Mingshu

    2011-08-01

    Full Text Available Abstract Background Previous studies have indicated that the UL16 protein and its homologs from herpesvirus were conserved and played similar roles in viral DNA packaging, virion assembly, budding, and egress. However, there was no report on the UL16 gene product of duck enteritis virus (DEV. In this study, we analyzed the amino acid sequence of UL16 using bioinformatics tools and expressed in Escherichia coli Rosetta (DE3 induced by isopropy1-β-D-thiogalactopyranoside (IPTG. The recombinant protein was produced, purified using a Ni-NTA column and used to generate the polyclonal antibody against UL16. The intracellular distribution of the DEV UL16 product was carried out using indirect immunofluorescence assay. Results In our study, UL16 gene of DEV was composed of 1089 nucleotides, which encoded 362 amino acids. Multiple sequence alignment suggested that the UL16 gene was highly conserved in herpesvirus family. The UL16 gene was cloned into a pET prokaryotic expression vector and transformed into Escherichia coli Rossetta (DE3 induced by IPTG. A 60kDa fusion protein band corresponding to the predicted size was produced on the SDS-PAGE, purified using a Ni-NTA column. Anti-UL16 polyclonal sera was prepared by immunizing rabbits, and reacted with a band in the IPTG induced cell lysates with an apparent molecular mass of 60 kDa. In vivo expression of the UL16 protein in DEV infected duck embryo fibroblast cells (DEFs was localized mostly around perinuclear cytoplasmic area and in cytosol using indirect immunofluorescence assay. Conclusions The UL16 gene of DEV was successfully cloned, expressed and detected in DEV infected DEFs for the first time. The UL16 protein localized mostly around perinuclear cytoplasmic area and in cytosol in DEV infected DEFs. DEV UL16 shared high similarity with UL16 family members, indicating that DEV UL16 many has similar function with its homologs. All these results may provide some insight for further research about

  9. Psychiatric Aspects of Childhood Epilepsy

    Directory of Open Access Journals (Sweden)

    Raman Deep PATTANAYAK

    2012-06-01

    2004;3(11:663-72.20. Bujoreanu, IS, Ibeziako P, DeMaso DR. Psychiatric concerns in pediatric epilepsy. Child Adolesc Psychiatr Clin N Am 2010;19(2:371-86.21. Hermann BP, Lin, JJ, Jones, JE, Seidenberg S. The emerging architecture of neuropsychological impairment in epilepsy. Neurol Clin 2009;27(4:881-907.22. Hermann B, Seidenberg M, Bell B, Rutecki P, Sheth R, Ruggles K, et al. The neurodevelopmental impact of childhood-onset temporal lobe epilepsy on brain structure and function. Epilepsia 2002;43(9:1062-71.23. Loring DW, Meador KJ. Cognitive side effects of antiepileptic drugs in children. Neurology 2004;62(6:872-7.24. McDermott S, Mani S, Krishnaswami S. A populationbased analysis of specific behavior problems associated with childhood seizures. J Epilepsy 1995;8:110-8.25. Davies S, Heyman I, Goodman, R. A population survey of mental health problems in children with epilepsy. Dev Med Child Neurol 2003;45(5:292-5.26. Kaufmann R, Goldberg-Stern H, Shuper A. Attentiondeficit disorders and epilepsy in childhood: incidence, causative relations and treatment possibilities. J Child Neurol 2009;24(6:727-33.27. Buelow JM, Austin JK, Perkins SM, Shen J, Dunn DW, Fastenau PS. Behavior and mental health problems in children with epilepsy and low IQ. Dev Med Child Neurol 2003;45(10:683-92.28.Williams J, Lange B, Phillips T, Sharp GB, DelosReyes E, Bates S, et al. The course of inattentive and hyperactiveimpulsive symptoms in children with new onset seizures. Epilepsy Behav 2002;3(6:517-21.29. Hermann B, Seidenberg M, Jones J. The neurobehavioural comorbidities of epilepsy: can a natural history be developed? Lancet Neurol 2008;7(2:151-60.30. Schoenfeld J, Seidenberg M, Woodard A, Hecox K, Inglese C, Mack K, et al. Neuropsychological and behavioral status of children with complex partial seizures. Dev Med Child Neurol 1999;41(11:724-31.31. Austin JK, Caplan R. Behavioral and psychiatric comorbidities in pediatric epilepsy: toward an integrative

  10. Frequency, Causes, and Findings of Brain CT Scans of Neonatal Seizure at Besat Hospital, Hamadan, Iran

    Directory of Open Access Journals (Sweden)

    Fateme EGHBALIAN*

    2015-01-01

    . Clin perinatal 2005; 24: 735-772.Lanska MJ, Lanska DJ, Baumann RJ, Kryscio RJ. A population-based study of neonatal seizures in Fayette County, Kentucky. Neurology 1995; 45:724-32.Ronen GM, Penney S, Andrews W. The epidemiology of clinical neonatal seizures in Newfoundland: a populationbased study. J Pediatr 1999; 134:71-5.Saliba RM, Annegers JF, Waller DK, et al. Incidence of neonatal seizures in Harris County, Texas, 1992-1994. Am J Epidemiol 1999; 150:763-9.Volpe JJ. Neonatal seizures. In: Neurology of the newborn. 5th ed. Philadelphia: WB Saunders. 2008. P. 203-44.Fanaroff AA, Martin RJ, Neonatal. Prenatal medicine. 8th ed. New York: Mosby, 2006; 956-976.Scher MS, Aso K, Beggarly ME, et al. Electrographic seizures in preterm and full-term neonates: clinical correlates, associated brain lesions, and risk for neurologic sequelae. Pediatrics 1993; 91:128-34.Tekgul H, Gauvreau K, Soul J, et al. The current etiologic profile and neurodevelopmental outcome of seizures in term newborn infants. Pediatrics 2006; 117:1270-80.Rogalski LI, Minokoshi M, Silveira DC, Cha BH, Holmes GL. Recurrent neonatal seizures: relationship of pathology to the electroencephalogram and cognition. Brain Res Dev Brain Res 2001; 129:27-38.Cilio MR, Sogawa Y, Cha BH, Liu X, Huang LT, Holmes GL. Long-term effects of status epilepticus in the immature brain are specific for age and model. Epilepsia 2003; 44:518-28.Lynch M, Sayin U, Bownds J, Janumpalli S, Sutula T. Long-term consequences of early postnatal seizures on hippocampal learning and plasticity. Eur J Neurosci 2000; 2:2252-64.Ni H, Jiang YW, Bo T, Wang JM, Wu XR. c-Fos, N-methyl-Diaspartate receptor 2C, GABA-A-a1 immunoreactivity, seizure latency, and neuronal injury following single or recurrent neonatal seizures in hippocampus of Wistar rat. Neurosci Lett 2005; 380:149-54.Bo T, Jiang Y, Cao H, Wang J, Wu X. Long-term effects of seizures in neonatal rats on spatial learning ability and N-methyl-D-aspartate receptor expression in the brain

  11. Clinical and Para clinical Manifestations of Tuberous Sclerosis: A Cross Sectional Study on 81 Pediatric Patients

    Directory of Open Access Journals (Sweden)

    Seyyed Hassan TONEKABONI

    2012-09-01

    -9.Lendvay TS, Marshall FF. The tuberous sclerosis complex and its highly variable manifestations. J Urol2003 May;169(5:1635-42.Curatolo P, Jóźwiak S, Nabbout R; on behalf of the participants of the TSC Consensus Meeting for SEGA and Epilepsy Management. Management of epilepsy associated with tuberous sclerosis complex (TSC:Clinical recommendations. Eur J Paediatr Neurol 2012Jun;16(1:83-5.Jansen FE, Van Huffelen AC, Van Rijen PC, LeijtenFS,Jennekens-Schinkel A, Gosselaar P et al. Epilepsy surgeryin tuberous sclerosis: the Dutch experience. Seizure 2007Jul;16(5:445-53.Turgut M, Akalan N, Ozgen T, Ruacan S, Erbengi A. Subepandymal giant cell astrocytoma associated with tuberous sclerosis: diagnostic and surgical characteristics of five cases with unusual features. Clin Neurol Neurosurg1996 Aug;98(3:217-21.Coppola G, Klepper J, Ammendola E, Fiorillo M, dellaCorte, Capano G. The effects of the ketogenic diet in refractory partial seizures with reference to tuberous sclerosis. Eur J Pediatr Neurol 2006 May;10(3:148-51.Jozwia S, Kotulska K, Domanska-Pakiela D, LojszczykB, Syczewska M et al. Antiepileptic treatment before the onset of seizure reduces epilepsy severity and risk of mental retardation in infants with tuberous sclerosis complex. Eur J Paediatr Neurol 2011 Sep;15(5:424-31.Konishi Y, Ito M, Okuno T, Hojo H, Okuda R, Nakano Yet al. Tuberous sclerosis: early neurologic manifestations and CT features in 18 patients. Brain Dev 1979;1(1:31-7.Gerard G, Weisberg L. Tuberous sclerosis: CT findings and differential diagnosis. Comput Radiol 1987 Jul-Aug;11(4:189-92.Pompili G, Zirpoli S, Sala C, Flor N, Alfano RM, Volpi A et al. Magnetic resonance imaging of renal involvementin genetically studied patients with tuberous sclerosis complex. Eur J Radiol 2009 Nov;72(2:335-41.Fleury P, de Groot Wp, Delleman JW, Verbeeten B Jr,Frankenmolen-Witkiezwicz IM. Tuberous sclerosis: theincidence of sporadic cases versus familial cases. BrainDev 1980;2(2:107-17.Saadat M, Ansari-Lari M, Farhud

  12. Infantile Spasm: A Review Article

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    Mohammad Mahdi TAGHDIRI

    2014-07-01

    pres; 2009. p. 593-7.Fujii, Oquni H, Hirano Y, Shioda M, Osawa M. A longterm, clinical study on symptomatic infantile spasm with focal features. Brain Dev 2013;35(5:379-85.SankarR, Koh S, Wu J. Menkes JH. Paroxysmal disorders. In: Menkes JH, Sarnat HB,. MariaBL, editors Child neurology. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2006. p. 857-942.Kendall Nash and Joseph Sullivan. Myoclonic seizures and infantile spasms. InSwaiman KF, Ashwal S, Ferriero DM, Schor NF, editors.. Swaiman’s pediatric Neurology: principles and practice. 5th ed. Edinburgh: Elsevier Saunders; 2012. p. 774-89.Paroxysmal Disorders. In: Piña-Garza J. Fenichel’s Clinical Pediatric Neurology. 7th ed. Elsevier Saunders; 2013. p. 1-46.Paciorkowski AR, Thio LL, Dobyns WB. Genetic and biologic classification of infantile spasms. Pediatr Neurol 2011;45(6:355-67.Manqanno S, Nardello R, Tripi G, Giordano G, Spitaleri C, Manfano GR. West Syndrome Followed by juvenile myoclonic epilepsy: a coincidental occurrence. BMC Neural 2013;13:48.LUX AL. Latest American and European update on infantile spasms. Curr Neural Neurosci Rep 2013;13(3:334.Hrachovy RA, Frost JD Jr. Infantile spasms. Handb Clin Neuro. 2013;111:611-8.Shumiloff NA, Lam WM, Manasco KB. Adrenocorticotropic hormone for the treatment of west syndrome in children. Ann Pharmacother 2013 47(5:744- 54.Wheless JW, Gibson PA, Rosbeck KL, Hardin M, O’Dell C, Whiltemore V. Infantile Spasms (west syndrome:  Update and resources for pediatricians and providers to share with parents. BMC Pediatr. 2012;12:108.Watemberg N. Infantile Spasms: treatment challenges. Curr Treat Options Neural. 2012;14(4: 322-31.Fukui M, Shimakawa S, Tanabe T, Nomura S, Kashiwagi M, Azumakawa K. Partial seizures during ACTH therapy in a cryptogenic West syndrome patient. Brain Dev 2013;Pii:s0387-7604(1300003-x.Friedman D, Boqner M, Parker-Menzer K, Dviskyo. Vigabatin for partial- onset seizure treatment in patients with tuberous sclerosis complex. Epilepsy Behav 2013

  13. Framework for automatic information extraction from research papers on nanocrystal devices.

    Science.gov (United States)

    Dieb, Thaer M; Yoshioka, Masaharu; Hara, Shinjiro; Newton, Marcus C

    2015-01-01

    To support nanocrystal device development, we have been working on a computational framework to utilize information in research papers on nanocrystal devices. We developed an annotated corpus called " NaDev" (Nanocrystal Device Development) for this purpose. We also proposed an automatic information extraction system called "NaDevEx" (Nanocrystal Device Automatic Information Extraction Framework). NaDevEx aims at extracting information from research papers on nanocrystal devices using the NaDev corpus and machine-learning techniques. However, the characteristics of NaDevEx were not examined in detail. In this paper, we conduct system evaluation experiments for NaDevEx using the NaDev corpus. We discuss three main issues: system performance, compared with human annotators; the effect of paper type (synthesis or characterization) on system performance; and the effects of domain knowledge features (e.g., a chemical named entity recognition system and list of names of physical quantities) on system performance. We found that overall system performance was 89% in precision and 69% in recall. If we consider identification of terms that intersect with correct terms for the same information category as the correct identification, i.e., loose agreement (in many cases, we can find that appropriate head nouns such as temperature or pressure loosely match between two terms), the overall performance is 95% in precision and 74% in recall. The system performance is almost comparable with results of human annotators for information categories with rich domain knowledge information (source material). However, for other information categories, given the relatively large number of terms that exist only in one paper, recall of individual information categories is not high (39-73%); however, precision is better (75-97%). The average performance for synthesis papers is better than that for characterization papers because of the lack of training examples for characterization papers

  14. Multiple Sclerosis in Children

    Directory of Open Access Journals (Sweden)

    Soroor INALOO

    2013-06-01

    Full Text Available How to Cite This Article: Inaloo S, Haghbin S. Multiple Sclerosis in Children. Iran J Child Neurol. 2013 Spring;7(2:1-10. Multiple sclerosis (MS is the most important immune-mediated demyelinated disease of human which is typically the disease of young adults. A total of 4% to 5% of MS population are pediatric. Pediatric MS is defined as the appearance of MS before the age of sixteen. About 80% of the pediatric cases and nearly all adolescent onset patients present with attacks typical to adult MS. Approximately 97% to 99% of the affected children have relapsing-remitting MS, while 85% to 95% of the adults experience such condition. MS in children is associated with more frequent and severe relapses. Treatment is the same as adults. We aimed to review the epidemiology, etiology, clinical manifestations, and treatment of MS in children. References1. Lublin F. History of modern multiple sclerosis therapy. J Neurol 2005 Sep;252(Suppl 3:iii3-iii9. Review.2. Murray TJ. Robert Carswell: the first illustrator of MS. Int MS J 2009 Sep;16(3:98-101.3. Kabat EA, Glusman M, Knaub V. Quantitative estimation of the albumin and gamma globulin in normal and pathologic cerebrospinal fluid by immunochemical methods. Am J Med 1948 May;4(5:653-62.4. Kumar DR, Aslinia F, Yale SH, Mazza JJ. Jean-Martin Charcot: the father of neurology. Clin Med Res 2011 Mar;9(1:46-9.5. Dawson JD. The histology of disseminated sclerosis.Trans of the Roy Soc Edinb. 1916;50:517-740.6. Gadoth N. Multiple sclerosis in children. Brain Dev 2003 Jun;25(4:229-32. Review.7. Banwell BL. Pediatric multiple sclerosis. Curr Neurol Neurosci Rep 2004 May;4(3:245-52.8. Renoux C, Vukusic S, Mikaeloff Y, Edan G, Clanet M, Dubois B, et al. Natural history of multiple sclerosis with childhood onset. N Engl J Med 2007 Jun 21;356(25:2603-13.9. Boiko A, Vorobeychicle G, Paty D, Devonshire V, Sondovnick D. Early onset multiple sclerosis: a long longitudinal study. Neurology 2002 Oct 8

  15. Evaluation of anti-leishmanial activity of artemisinin combined with amphotericin B or miltefosine in Leishmania donovani promastigotes

    Directory of Open Access Journals (Sweden)

    Musfikur Rahaman

    2014-08-01

    Conclusions: This study supports the combination use of artemisinin-amphotericin B and artemisinin-miltefosine, worthy of future pharmacological consideration. [Int J Basic Clin Pharmacol 2014; 3(4.000: 644-648

  16. Wound healing suppressant effect of vincristine reversed by vitamin A: an experimental study

    Directory of Open Access Journals (Sweden)

    Venkatadri T.V.

    2016-06-01

    Conclusions: Vitamin A by itself produced little effect on healing except a modest increase in granulation mass. But it significantly reversed the healing suppressant effects of vincristine. [Int J Basic Clin Pharmacol 2016; 5(3.000: 962-964

  17. Disease: H01049 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available imi LA, Yawetz S, Lasker BA, Bolcen SJ, Brown JM, Marty FM Gordonia bronchialis bacteremia and pleural infection: case report and rev...iew of the literature. J Clin Microbiol 49:1662-6 (2011) ...

  18. Disease: H01057 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available gon BL Gnathostomiasis: a review of a previously localized zoonosis now crossing ...actor) Rusnak JM, Lucey DR Clinical gnathostomiasis: case report and review of the English-language literature. Clin Infect Dis 16:33-50 (1993) ...

  19. Disease: H00156 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available osity. Clin Exp Nephrol 11:174-9 (2007) PMID:15630634 Smelt AH, de Beer F Apolipoprotein E and familial dysbetalipoproteinemia: clini...cal, biochemical, and genetic aspects. Semin Vasc Med 4:249-57 (2004) ...

  20. Genetics Home Reference: X-linked agammaglobulinemia

    Science.gov (United States)

    ... Modell Foundation: National Primary Immunodeficiency Resource Center National Organization for Rare Disorders : ... V, Aiba Y, Shurtleff SA, Kurosaki T. A minimally hypomorphic mutation in Btk resulting in reduced B cell numbers but no clinical disease. Clin Exp Immunol. ...

  1. The Use of Patient-Specific Intra-Operative Guides for Total Knee Arthroplasty (TKA

    Directory of Open Access Journals (Sweden)

    Hendrik P. Delport

    2012-08-01

    Conclusions: We conclude that this novel technique hereby described has major benefits: less operative time and proper implant positioning, but more prospective studies are mandatory. [Arch Clin Exp Surg 2012; 1(4.000: 206-212

  2. Disease: H00348 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 34 McPhee SJ, Papadakis MA, Tierney LM (ed). Current Medical Diagnosis & Treatmen...matis infections. Clin Microbiol Infect 15:4-10 (2009) PMID:8993862 (description) Black CM Current methods o

  3. Disease: H00347 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available s: 000659 000439 McPhee SJ, Papadakis MA, Tierney LM (ed). Current Medical Diagno...lamydia trachomatis infections. Clin Microbiol Infect 15:4-10 (2009) PMID:8993862 (description) Black CM Current

  4. Comparison of the acute effects of hemostatic agents on neural tissues in spine surgery: Histologic analysis in rat models

    Directory of Open Access Journals (Sweden)

    Gokhan Meric

    2016-03-01

    Conclusion: Both gelatin sponge and oxidized cellulose did not increase the cellular necrosis of neural tissues. However, oxidized cellulose may lead to an increased local inflammatory reaction. [Arch Clin Exp Surg 2016; 5(1.000: 21-26

  5. Awareness of adverse drug reactions in third M.B.B.S students practicing self-medication

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    Shreyas R. Burute

    2016-02-01

    Conclusions: Considering the wide range of drugs consumed, the numbers of ADRs mentioned were few and their spectrum limited indicating scope for improvement. [Int J Basic Clin Pharmacol 2016; 5(1.000: 196-201

  6. Innovative first order elimination kinetics working model for easy learning

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    Navin Budania

    2016-06-01

    Conclusions: First order elimination kinetics is easily understood with the help of above working model. More and more working models could be developed for teaching difficult topics. [Int J Basic Clin Pharmacol 2016; 5(3.000: 862-864

  7. Disease: H00373 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D:16288402 (description, drug) Nalca A, Rimoin AW, Bavari S, Whitehouse CA Reemergence of monkeypox: preva...lence, diagnostics, and countermeasures. Clin Infect Dis 41:1765-71 (2005) PMID:176

  8. The practice-unit centered clinical database--the implementation.

    OpenAIRE

    Bryner, U. M.

    1991-01-01

    A clinical database system under the name ClinTrac has been developed for the purpose of acquiring, processing, storing, analyzing, and communicating clinical information. The core of this system consists of a practice-unit centered database.

  9. Drug utilization pattern of analgesics in various departments of a tertiary care teaching rural dental hospital

    Directory of Open Access Journals (Sweden)

    Nirav N. Patel

    2014-10-01

    Conclusions: Drug utilization data can help to formulate appropriate clinical guidelines for drug use and facilitate rational use of medicines in population. [Int J Basic Clin Pharmacol 2014; 3(5.000: 804-806

  10. Disease: H01084 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available [Bordetella holmesii bacteremia in a child with sickle cell disease]. Enferm Infecc Microbiol Clin 29:779-80...Saint Jean M, Brun D, Guiso N, Bekal S, Ovetchkine P, Tapiero B Bordetella holmesii bacteremia in asplenic child

  11. Disease: H00485 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00485 Robinow syndrome Robinow syndrome is characterized by distinctive craniofacial...hn MT, Cunningham ML, Petryk A, Lohr JL Craniofacial and intraoral phenotype of Robinow syndrome forms. Clin Genet 80:15-24 (2011) ...

  12. Medications package inserts' usefulness to doctors and patients: Sudanese doctors perspective

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    Kamal Addin Mohammad Ahmad Idris

    2014-08-01

    Conclusion: Doctors should give more attention to their patients' medication information specific needs, advice and motivate them to read the PIs before using their medications. [Int J Basic Clin Pharmacol 2014; 3(4.000: 718-722

  13. Crinum zeylanicum memory enhancing effect is mediated via central cholinergic transmission system

    Directory of Open Access Journals (Sweden)

    Tijani Adeniyi Yahaya

    2015-10-01

    Conclusion: The extract, as well as its partially purified alkaloid, possesses potential that may be employed for therapeutic management of Alzheimer's disease. [Int J Basic Clin Pharmacol 2015; 4(5.000: 864-868

  14. Hepatoprotective activity of methanolic leaves extract of Rostellularia procumbens by using carbon tetrachloride intoxicated rats

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    M. Mamatha

    2014-12-01

    Conclusion: The results confirm that R. procumbens have hepatoprotective activity against CCl4 induced hepatotoxicity and significant hepatoprotection seen at 500 mg/kg dose. [Int J Basic Clin Pharmacol 2014; 3(6.000: 964-969

  15. An open-label study to assess the effect of a single dose of Nebivolol and Ivabradine on heart rate and pulse wave velocity in hypertensive patients receiving amlodipine

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    Rama Mohan Pathapati

    2015-04-01

    Conclusions: Nebivolol is an effective HR lowering agent compared to Ivabradine. However, significant decrease in arterial stiffness was observed with Ivabradine. [Int J Basic Clin Pharmacol 2015; 4(2.000: 219-223

  16. Study of prescription pattern and adverse drug reactions in patients with cervical cancer in tertiary care teaching institute

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    Ankita Sunilrao Jire

    2016-08-01

    Conclusions: Among patients with CA cervix, cisplatin was most commonly prescribed drug. Nausea was most common ADR which is of and lsquo;mild level 1' severity. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1594-1597

  17. Anti-inflammatory potential of Agaricus in carrageenan-induced model of local inflammation in rats

    Directory of Open Access Journals (Sweden)

    Abdelrazzag A. Elmajdoub

    2015-06-01

    Conclusions: These data may indicate that Agaricus extract has the potential of anti-inflammatory activity that could be applied in acute inflammatory disorders. [Int J Basic Clin Pharmacol 2015; 4(3.000: 497-502

  18. Disease: H01199 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01199 Hyperalphalipoproteinemia Hyperalphalipoproteinemia (HALP) is a condition of...fication of an apolipoprotein C-III variant in a family with hyperalphalipoproteinemia. J Clin Invest 87:1724-31 (1991) ...

  19. Effect of oxytetracycline and doxycycline on muscle tone in healthy human volunteers

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    Savitri Katlam

    2016-08-01

    Conclusions: Use of oxytetracycline is associated with reduced grip strength in healthy human volunteers. These findings have potential implication on the functional ability of muscle. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1559-1562

  20. Comparative efficacy of inhaled ciclesonide, budesonide, and fluticasone in mild to moderately persistent bronchial asthma

    Directory of Open Access Journals (Sweden)

    Tamoghna Maiti

    2014-10-01

    Conclusion: Steroid therapy along with beta2-agonists showed a significant improvement in symptoms. There was no difference among the three different types of steroids. [Int J Basic Clin Pharmacol 2014; 3(5.000: 836-839

  1. Prolactinoma

    Science.gov (United States)

    ... JK. Update on prolactinomas. Part 2: Treatment and management strategies. J Clin Neurosci . 2015;22:1568-1574. PMID: 26243714 ... by: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University ...

  2. Cardiovascular and biochemical studies on the effects of thrombin and dabigatran and the interaction with vasopressor molecules

    Directory of Open Access Journals (Sweden)

    R. Anand

    2014-10-01

    Conclusion: The thrombin inhibitor, dabigatran reduces vascular oxidative stress and inflammation, improves endothelial function, and decreases atherosclerosis in rodents. [Int J Basic Clin Pharmacol 2014; 3(5.000: 874-878

  3. Comparison of efficacy of telmisartan with losartan in patients of essential hypertension with cognitive impairment

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    Nitin Natthuji Puram

    2016-06-01

    Conclusions: Telmisartan is as effective as losartan in controlling blood pressure and improving cognitive function in hypertensive patients with cognitive impairment. [Int J Basic Clin Pharmacol 2016; 5(3.000: 702-706

  4. Antidiabetic effect of 2 nitro benzimidazole in alloxan induced diabetic rats

    Directory of Open Access Journals (Sweden)

    Prapthi Bathini

    2013-12-01

    Conclusion: 2 nitro benzimidazole exhibited significant antihyperglycemic activity in alloxan-induced diabetic rats comparable to that of the standard drug glibenclamide. [Int J Basic Clin Pharmacol 2013; 2(6.000: 814-818

  5. Disease: H00099 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available R, Brennan T, Curtis J, Reichert V, Hovhannisyan H, Majzoub J, Miller DT. Genetic...iencies. Mayo Clin Proc 73:865-72 (1998) PMID:18424339 (gene) Morra M, Geigenmuller U, Curran J, Rainville I

  6. Comparative evaluation of H1 receptor blocking activity and safety of newer H1antagonist mizolastine with loratadine and placebo: a randomized double blind three way crossover study

    Directory of Open Access Journals (Sweden)

    K. Swarnalatha

    2016-06-01

    Conclusions: Mizolastine has good antihistaminic activity than loratadine. Neither drug causes any psychomotor impairment or has anti-cholinergic action. [Int J Basic Clin Pharmacol 2016; 5(3.000: 661-675

  7. Disease: H00317 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available seudomallei. Nat Rev Microbiol 4:272-82 (2006) PMID:15831829 (env_factor) Cheng AC, Currie BJ Melioidosis: epidemiology, pathophysiol...ogy, and management. Clin Microbiol Rev 18:383-416 (2005) PMID:20192686 (drug) Este

  8. Effect of Lagenaria siceraria fruit extract (Bottle gourd on hepatotoxicity induced by antitubercular drugs in albino rats

    Directory of Open Access Journals (Sweden)

    Satyajeet K. Funde

    2013-12-01

    Conclusion: Ethanolic extract of Lagenaria siceraria fruit possesses significant hepatoprotective and antioxidant activity in antitubercular drugs induced hepatotoxicity. [Int J Basic Clin Pharmacol 2013; 2(6.000: 728-734

  9. Antihypertensive and antiatherogenic effects of Tanopati a traditional recipe used for the treatment of high blood pressure

    Directory of Open Access Journals (Sweden)

    Amani Komenan Nazaire

    2016-10-01

    Conclusions: The results obtained confirm the antihypertensive effect of Tanopati and justify it traditionally use in treatment of high blood pressure. [Int J Basic Clin Pharmacol 2016; 5(5.000: 1903-1909

  10. Disease: H01357 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Contact dermatitis. Clin Dermatol 18:661-6 (2000) PMID:15243515 (env_factor) Cohen DE Contact dermatitis: a quarter century perspecti...ve. J Am Acad Dermatol 51:S60-3 (2004) PMID:24193097 (en

  11. Disease: H01360 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available on disease, present treatments and future prospects. Int Immunopharmacol 11:1646-62 (2011) PMID:18360551 (e...ar R Allergic rhinitis: current options and future perspectives. Curr Opin Allergy Clin Immunol 14:168-76 (2014) ...

  12. Evaluation of antidepressant activity of ondansetron alone and in combination with fluoxetine-an experimental study

    Directory of Open Access Journals (Sweden)

    Sonal M. Parekar

    2016-02-01

    Conclusions: Our study concludes that ondansetron alone and in combination with fluoxetine possesses significant antidepressant activity in animal models of depression. [Int J Basic Clin Pharmacol 2016; 5(1.000: 90-97

  13. Disease: H01041 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available s to gram-positive coccus. Most infections are mild, but fatal infections such as endocarditis with high rat...ococcus urinae: severe and fatal bloodstream infections and endocarditis. J Clin

  14. Comparison of cardiovascular safety of escitalopram and sertraline based on electrocardiographic alterations: a pharmacovigilance study

    Directory of Open Access Journals (Sweden)

    Balwant K. Choure

    2016-08-01

    Conclusions: It was concluded, at therapeutic doses neither of the drugs have the potential risk of drug induced arrhythmias, throughout the study. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1193-1200

  15. To evaluate and compare the hypoglycemic, antioxidant and hypolipidemic effect of lycopene with atorvastatin in hyperlipidemic New Zealand white rabbits

    Directory of Open Access Journals (Sweden)

    Sarita Mulkalwar

    2015-02-01

    Conclusion: Findings suggest that lycopene may have considerable therapeutic benefit as an antioxidant and hypolipidemic agent, but may not be effective as a hypoglycemic agent. [Int J Basic Clin Pharmacol 2015; 4(1.000: 148-152

  16. Effects of sildenafil on lipid profile and glycemic control in patients with type 2 diabetes mellitus and metabolic syndrome

    Directory of Open Access Journals (Sweden)

    Haedar Abdulhafith Al-biati

    2014-12-01

    Conclusion: We have provided the first evidence that sildenafil therapy improve glycemic control, lipid profile and body mass index in diabetic patients with metabolic syndrome. [Int J Basic Clin Pharmacol 2014; 3(6.000: 1048-1051

  17. Evaluation of neuroprotective effect of flupirtine in brain of albino rats

    Directory of Open Access Journals (Sweden)

    Elango P

    2016-02-01

    Conclusions: This study represents the neuroprotective characteristics of flupiritne against the excitotoxicity induced by NMDA in an in vivo rat models. [Int J Basic Clin Pharmacol 2016; 5(1.000: 135-141

  18. Effect of nimodipine and flunarizine on neuromuscular function in mice

    Directory of Open Access Journals (Sweden)

    Swapnil B. Kaikade

    2016-08-01

    Conclusions: Nimodipine has significant dose dependent depressant action on neuromuscular function while flunarizine has no effect on the above mentioned parameter. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1524-1527

  19. Evaluation of effect of alcoholic extract of Tinospora cordifolia on learning and memory in alprazolam induced amnesia in albino mice

    Directory of Open Access Journals (Sweden)

    Jyothi C. H.

    2016-10-01

    Conclusions: Tinospora cordifolia, Indian medicinal plant useful for treatment of various ailments can also be a useful alternative for treating dementia and associated diseases like alzheimer's disease. [Int J Basic Clin Pharmacol 2016; 5(5.000: 2159-2163

  20. Disease: H00419 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00419 Congenital generalized lipodystrophy (CGL) Congenital generalized lipodystrophy...o H, Nishino I Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy. J Clin Invest 119:2623-33 (2009) ...

  1. Disease: H00356 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 8 (description, env_factor, comment) Collinet-Adler S, Ward HD Cryptosporidiosis: environmental, therapeutic, and preventive challeng...es. Eur J Clin Microbiol Infect Dis 29:927-35 (2010) PMID:12686887 (description, en

  2. The efficacy and safety of clomiphene citrate and metformin on ovulation induction in patients suffering from anovulatory infertility

    Directory of Open Access Journals (Sweden)

    Hardik Patel

    2015-12-01

    Conclusion: Ovulation rate was significantly higher compared to pregnancy rate. We could not find any benefit of adding metformin to the standard treatment with clomiphene citrate. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1241-1246

  3. A randomized, open-labelled study of the sedative, analgesic and anxiolytic effect of dexmedetomidine and tramadol in postoperative patients

    Directory of Open Access Journals (Sweden)

    Padma L

    2013-12-01

    Conclusion: Though there is no statistical difference in both groups, dexmedetomidine significantly reduced anxiety, agitation and produced calmness in postoperative patients which was not seen with tramadol. [Int J Basic Clin Pharmacol 2013; 2(6.000: 804-809

  4. Anterior knee pain

    Science.gov (United States)

    Patellofemoral syndrome; Chondromalacia patella; Runner's knee; Patellar tendinitis; Jumper's knee ... Collado H, Fredericson M. Patellofemoral pain syndrome. Clin Sports ... www.ncbi.nlm.nih.gov/pubmed/20610028 . De Carlo M, Armstrong ...

  5. A study on drug prescribing pattern in psychiatry out-patient department from a tertiary care teaching hospital

    Directory of Open Access Journals (Sweden)

    Sonali B. Rode

    2014-06-01

    Conclusion: Utilization pattern of the psychotropic drugs were in accordance to the recommendations of various treatment guidelines. BZD were the most commonly prescribed psychotropic drugs. [Int J Basic Clin Pharmacol 2014; 3(3.000: 517-522

  6. Regulation of wound strength by Ocimum sanctum: in silico and in vivo evidences

    Directory of Open Access Journals (Sweden)

    Amit Singh

    2014-02-01

    Conclusions: The present study is an attempt to correlate the in vivo findings on wound strength promoting activity by Ocimum sanctum with in silico tools. [Int J Basic Clin Pharmacol 2014; 3(1.000: 179-185

  7. Short stature

    Science.gov (United States)

    ... Endocrine Society, and the European Society for Paediatric Endocrinology Workshop. J Clin Endocrinol Metab . 2008;93(11): ... Larsen PR, Kronenberg HM, eds. Williams Textbook of Endocrinology . 12th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap ...

  8. A study to assess the effect of vitamin D supplementation on insulin resistance and glycaemic control in type 2 diabetes mellitus patients

    Directory of Open Access Journals (Sweden)

    Parminder K. Dhillon

    2016-04-01

    Conclusions: The study showed that vitamin D supplementation improves the glycaemic control and insulin sensitivity in type 2 diabetes mellitus patients. [Int J Basic Clin Pharmacol 2016; 5(2.000: 466-472

  9. Disease: H00084 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available bone marrow transplant. Annu Rev Med 54:29-52 (2003) PMID:15931364 (drug) Iwasaki T. Recent advances in the treatment of graft-versus-host disease. Clin Med Res 2:243-52 (2004) ...

  10. Interaction of two memory enhancing herbal drugs Memory Plus and Mentat with diazepam and phenytoin sodium in mice

    Directory of Open Access Journals (Sweden)

    Neera R. Gupta

    2015-04-01

    Conclusion: Subchronic administration of MP and Mentat shows significant interaction with diazepam and PS. Further human studies are warranted to confirm these findings. [Int J Basic Clin Pharmacol 2015; 4(2.000: 203-207

  11. Assessment of Curcuma longa linn. on learning and memory in rats

    Directory of Open Access Journals (Sweden)

    K. Lohit

    2015-12-01

    Conclusion: C. longa linn. may be useful in enhancing learning. Further dose ranging preclinical studies are required to evaluate the efficacy of curcumin on memory. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1086-1090

  12. Expanding n-gram training data for language models based on morpho-syntactic transformations

    OpenAIRE

    Verwimp, Lyan; Pelemans, Joris; Hamme, Hugo Van; Wambacq, Patrick

    2015-01-01

    Verwimp L., Pelemans J., Van hamme H., Wambacq P., ''Expanding n-gram training data for language models based on morpho-syntactic transformations'', Computational linguistics in the Netherlands journal (CLIN journal), vol. 5, pp. 49-64, 2015.

  13. A cross-sectional study on knowledge, attitude, and behavior related to antibiotic use among undergraduate medical students in a tertiary care medical college, Kashmir

    Directory of Open Access Journals (Sweden)

    Shakeel Ahmad Mir

    2015-12-01

    Conclusions: There is an urgent need to improve education on antibiotic use in medical curricula. Furthermore, strict policies must be enforced to regulate dispensing of antibiotics. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1156-1162

  14. Disease: H00322 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ettsial infections--a threat to travellers? Curr Opin Infect Dis 17:433-7 (2004) PMID:15546086 Jensenius M, ...Fournier PE, Raoult D Rickettsioses and the international traveler. Clin Infect D

  15. A study of effect of Nigella sativa oil in paracetamol induced hepatotoxicity in albino rats

    Directory of Open Access Journals (Sweden)

    Manik S. Ghadlinge

    2014-06-01

    Conclusion: This study demonstrated that NS oil has hepatoprotective effect. NS oil administration can prevent or reverse the hepatotoxicity induced by paracetamol. [Int J Basic Clin Pharmacol 2014; 3(3.000: 539-546

  16. Effect of co-administration of voglibose and vildagliptin on diabetic albino rats

    Directory of Open Access Journals (Sweden)

    Umashanker PD Keshri

    2016-08-01

    Conclusions: Vildagliptin and voglibose are effective in lowering blood glucose level in albino diabetic rats but their combination has potentiating effect. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1533-1538

  17. Genetics Home Reference: epidermolysis bullosa simplex

    Science.gov (United States)

    ... mutations: new phenotypes and new mutations. Br J Dermatol. 2013 Apr;168(4):808-14. doi: 10. ... epidermolysis bullosa: new diagnostic criteria and classification. Clin Dermatol. 2012 Jan-Feb;30(1):70-7. doi: ...

  18. Genetics Home Reference: familial pityriasis rubra pilaris

    Science.gov (United States)

    ... review of diagnosis and treatment. Am J Clin Dermatol. 2010;11(3):157-70. doi: 10.2165/ ... Srivastava G. (Juvenile) Pityriasis rubra pilaris. Int J Dermatol. 2006 Apr;45(4):438-46. Review. Citation ...

  19. Genetics Home Reference: nonbullous congenital ichthyosiform erythroderma

    Science.gov (United States)

    ... congenital ichthyosiform erythroderma and lamellar ichthyosis. Clin Exp Dermatol. 2003 May;28(3):235-40. Review. Citation ... ichthyoses: the underlying genetic defects and pathomechanisms. J Dermatol Sci. 2006 May;42(2):83-9. Epub ...

  20. Sunburn

    Science.gov (United States)

    ... HI. Management of acute sunburn. Am J Clin Dermatol . 5(1):39-47, 2004. Last Updated: 22 ... these advertising practices and to make choices about online behavioral advertising, please click here . This site complies ...

  1. Disease: H00045 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available rug) Skeel RT (ed). Handbook of Cancer Chemotherapy, Sixth Edition Lippincott Williams & Wilkins (2003) ... ...lity of Ki-67 as a prognostic marker in pancreatic endocrine neoplasms. Am J Clin Pathol 109:245-7 (1998) (d

  2. An overview of drugs approved in India from 1999 through 2015

    Directory of Open Access Journals (Sweden)

    Vihang S. Chawan

    2015-08-01

    Conclusions: Thus, the present study highlights the changing scenario of drug approval, with few drugs being approved for clinical practice in the last 3 years. [Int J Basic Clin Pharmacol 2015; 4(4.000: 697-700

  3. Evaluation of pharmacology teaching-learning methods in a government medical college

    Directory of Open Access Journals (Sweden)

    Aritra Ghosh

    2016-02-01

    Conclusions: This study helps in knowing students' opinion and preferences in curriculum to make it more interesting and aids to modify the undergraduate Pharmacology teaching pattern. [Int J Basic Clin Pharmacol 2016; 5(1.000: 126-130

  4. Comparative study of anaphylaxis incidence in patients receiving anti-snake venom with or without prophylactic adrenaline: a prospective, randomized, blinded study

    Directory of Open Access Journals (Sweden)

    Raghuraman M. S.

    2016-08-01

    Conclusions: Prophylactic subcutaneous adrenaline before anti snake venom administration is highly efficacious and safe in reducing the incidence as well as severity of anaphylactic reactions. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1436-1440

  5. Eye of horus and ndash; Erratum revealed a prescription survey

    Directory of Open Access Journals (Sweden)

    M. J. Jijin

    2014-12-01

    Conclusions: The present data shows most prescriptions in the study was inadequate and important details were lacking, legibility of prescription was poor in rating. [Int J Basic Clin Pharmacol 2014; 3(6.000: 1016-1019

  6. Impact of teaching session on concepts of palliative care in medical undergraduates.

    Directory of Open Access Journals (Sweden)

    Sirisha Annavarapu

    2016-02-01

    Conclusions: Concept of palliative care was poor among medical undergraduates. Health care providers can overcome by knowledge construction, interrelation between practice and evidence based medicine. [Int J Basic Clin Pharmacol 2016; 5(1.000: 188-191

  7. Perceptions and suggestions of second year medical professional students of deemed health university about their teaching and learning process in pharmacology: an analytical study

    Directory of Open Access Journals (Sweden)

    Nagapati Prabhakar Bhat

    2016-06-01

    Conclusions: This study has helped us in knowing the student preferences regarding pharmacology teaching and its outcomes would be helpful in modifying undergraduate pharmacology teaching pattern. [Int J Basic Clin Pharmacol 2016; 5(3.000: 763-768

  8. Disease: H01218 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ies: 2009 update. J Allergy Clin Immunol 124:1161-78 (2009) PMID:19811314 (gene) Rezaei N, Moazzami K, Aghamohammadi A, Klein C Neutr...openia and primary immunodeficiency diseases. Int Rev Im

  9. Comparative study of problem based learning versus structured group discussion in teaching pharmacology

    Directory of Open Access Journals (Sweden)

    Laveesh M. R.

    2016-10-01

    Conclusions: PBL and SGD are effective small group methods for teaching undergraduate medical students. However learning outcome with PBL is better than SGD. [Int J Basic Clin Pharmacol 2016; 5(5.000: 1877-1880

  10. Disease: H00088 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00088 Common variable immunodeficiency (CVID), including the following four diseases...SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin ..., Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of Immunological Soc

  11. Photocarcinogenesis and toxicity of benzoyl peroxide in hairless mice after simulated solar radiation

    DEFF Research Database (Denmark)

    Lerche, Catharina M; Philipsen, Peter A; Poulsen, Thomas;

    2010-01-01

    Topical benzoyl peroxide (BPO) gel has long been used to treat acne vulgaris and has recently been combined with clindamycin (BPO-clin). No skin malignancies have been reported after clinical use of BPO, but there has been concern about the possible carcinogenicity of BPO alone and in combination...... with UV radiation. BPO can promote skin tumorigenesis in a mouse skin chemical carcinogenesis model. As acne vulgaris is frequently localized on sun-exposed areas, we investigated whether BPO or BPO-clin accelerates photocarcinogenesis in combination with simulated solar radiation (SSR) in 12 groups of 25...... hairless female C3.Cg/TifBomTac-immunocompetent mice. BPO or BPO-clin was applied topically to the back five times each week, followed by SSR three times each week (2, 3, or 4 standard erythema doses) 3-4 h later, for 365 days or until death. Generally BPO and BPO-clin did not accelerate the time to first...

  12. Genetics Home Reference: familial atrial fibrillation

    Science.gov (United States)

    ... or Free article on PubMed Central Roberts R. Mechanisms of disease: Genetic mechanisms of atrial fibrillation. Nat Clin Pract Cardiovasc Med. ... with a qualified healthcare professional . About Genetics Home Reference Site Map Contact Us Selection Criteria for Links ...

  13. Genetics Home Reference: congenital hyperinsulinism

    Science.gov (United States)

    ... Z, Arya VB, Hussain K. Hyperinsulinaemic hypoglycaemia:genetic mechanisms, diagnosis and management. J Clin Res Pediatr Endocrinol. ... Shyng SL, Stanley CA. Clinical characteristics and biochemical mechanisms of congenital hyperinsulinism associated with dominant KATP channel ...

  14. Drug utilization pattern of antidiabetic agents in a tertiary care hospital of western Odisha, India

    Directory of Open Access Journals (Sweden)

    Ratna Agrawal

    2016-10-01

    Conclusions: The prescribing trend has been monotherapy with insulin followed by oral antidiabetic drugs in the form of glimepiride and metformin combination. [Int J Basic Clin Pharmacol 2016; 5(5.000: 2222-2226

  15. Initial Pseudomonas aeruginosa infection in patients with cystic fibrosis: characteristics of eradicated and persistent isolates

    DEFF Research Database (Denmark)

    Tramper-Stranders, G. A.; van der Ent, C. K.; Molin, Søren;

    2012-01-01

    Clin Microbiol Infect 2012; 18: 567574 Abstract Despite intensive eradication therapy, some CF patients with early Pseudomonas aeruginosa infection rapidly develop a chronic infection. To elucidate factors associated with this persistence, bacterial characteristics of early P. aeruginosa isolates...

  16. Analgesic and antioxidant activities of the methanolic extract of Operculina turpethum leaves in mice

    Directory of Open Access Journals (Sweden)

    Maxwell I. Ezeja

    2015-06-01

    Conclusion: The study showed that O. turpethum possesses analgesic and antioxidant properties and confirmed the folkloric use of O. turpethum leaves in the traditional pain management. [Int J Basic Clin Pharmacol 2015; 4(3.000: 453-457

  17. Soy Allergy

    Science.gov (United States)

    ... cheese, soy fiber, soy flour, soy grits, soy ice cream, soy milk, soy nuts, soy sprouts, soy yogurt) ... Kaeding AJ, Matsui EC, Wood RA. The natural history of soy allergy. J Allergy Clin Immunol, 2010; ...

  18. Evaluation of analgesic activity of Aegle marmelos steam bark in experimental animals

    Directory of Open Access Journals (Sweden)

    Sarang Gajanan Ghodki

    2016-06-01

    Conclusions: AMSBAE has analgesic activity. The analgesic activity of AMSBAE was comparable to that of tramadol and Aspirin. Hence, AMSBAE could be a possible alternative to NSAIDs. [Int J Basic Clin Pharmacol 2016; 5(3.000: 1081-1086

  19. Disease: H01154 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available a type electrocardiographic changes induced by concomitant use of lithium and propafenone in patient with Wolff-Parkinson-White syndrome. Pacing Clin Electrophysiol 30:823-5 (2007) ...

  20. Disease: H00292 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available R, Woo A, Ralph-Edwards A, Butany J Hypertrophic cardiomyopathy: current understanding and treatment objec...tives. J Clin Pathol 62:226-35 (2009) PMID:19568388 (drug) Marian AJ Contemporary t

  1. Evaluation of second year MBBS students perceptions and experiences towards tutorials as a teaching-learning method in pharmacology

    Directory of Open Access Journals (Sweden)

    Ravindra S. Beedimani

    2016-06-01

    Conclusions: The suggestions based on feedback from learners, should be kept in mind while conducting tutorials to make it fruitful experience for MBBS students. [Int J Basic Clin Pharmacol 2016; 5(3.000: 1112-1117

  2. Pharmacokinetics and clinical evaluations of gentamicin-induced nephrotoxicity in puppies

    Directory of Open Access Journals (Sweden)

    Fidelis A. Gberindyer

    2015-08-01

    Conclusion: These suggest the risk of nephrotoxicity following treatment with gentamicin beyond 5 consecutive days irrespective of the dosing interval in puppies. [Int J Basic Clin Pharmacol 2015; 4(4.000: 691-696

  3. Comparative study to evaluate the anti-diabetic activity of commercially available extract of Tinospora cordifolia and Phyllanthus emblica in streptozocin induced diabetic rat

    Directory of Open Access Journals (Sweden)

    Nishant Pathak

    2016-08-01

    Conclusions: Commercially available extract of Tinospora cordifolia and Phyllanthus emblica have significant anti-diabetic activity in streptozocin induced diabetic rats. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1641-1646

  4. Decreasing candidaemia rate in abdominal surgery patients after introduction of fluconazole prophylaxis*

    DEFF Research Database (Denmark)

    Holzknecht, Barbara; Thorup, Jens Frederik; Arendrup, M C;

    2011-01-01

    Clin Microbiol Infect ABSTRACT: Although abdominal surgery is an established risk factor for invasive candidiasis, the precise role of antifungal prophylaxis in these patients is not agreed upon. In 2007, fluconazole was added to the prophylactic antibiotic treatment for patients with gastrointes......Clin Microbiol Infect ABSTRACT: Although abdominal surgery is an established risk factor for invasive candidiasis, the precise role of antifungal prophylaxis in these patients is not agreed upon. In 2007, fluconazole was added to the prophylactic antibiotic treatment for patients...

  5. Dielectric elastomer vibrissal system for active tactile sensing

    Science.gov (United States)

    Conn, Andrew T.; Pearson, Martin J.; Pipe, Anthony G.; Welsby, Jason; Rossiter, Jonathan

    2012-04-01

    Rodents are able to dexterously navigate confined and unlit environments by extracting spatial and textural information with their whiskers (or vibrissae). Vibrissal-based active touch is suited to a variety of applications where vision is occluded, such as search-and-rescue operations in collapsed buildings. In this paper, a compact dielectric elastomer vibrissal system (DEVS) is described that mimics the vibrissal follicle-sinus complex (FSC) found in rodents. Like the vibrissal FSC, the DEVS encapsulates all sensitive mechanoreceptors at the root of a passive whisker within an antagonistic muscular system. Typically, rats actively whisk arrays of macro-vibrissae with amplitudes of up to +/-25°. It is demonstrated that these properties can be replicated by exploiting the characteristic large actuation strains and passive compliance of dielectric elastomers. A prototype DEVS is developed using VHB 4905 and embedded strain gauges bonded to the root of a tapered whisker. The DEVS is demonstrated to produce a maximum rotational output of +/-22.8°. An electro-mechanical model of the DEVS is derived, which incorporates a hyperelastic material model and Euler- Bernoulli beam equations. The model is shown to predict experimental measurements of whisking stroke amplitude and whisker deflection.

  6. Discrete-event modeling and simulation a practitioner's approach

    CERN Document Server

    Wainer, Gabriel A

    2009-01-01

    Complex artificial dynamic systems require advanced modeling techniques that can accommodate their asynchronous, concurrent, and highly non-linear nature. Discrete Event systems Specification (DEVS) provides a formal framework for hierarchical construction of discrete-event models in a modular manner, allowing for model re-use and reduced development time.Discrete Event Modeling and Simulation presents a practical approach focused on the creation of discrete-event applications. The book introduces the CD++ tool, an open-source framework that enables the simulation of discrete-event models. After setting up the basic theory of DEVS and Cell-DEVS, the author focuses on how to use the CD++ tool to define a variety of models in biology, physics, chemistry, and artificial systems. They also demonstrate how to map different modeling techniques, such as Finite State Machines and VHDL, to DEVS. The in-depth coverage elaborates on the creation of simulation software for DEVS models and the 3D visualization environment...

  7. 鸭病毒性肠炎病毒CH强毒株适应在鸭胚成纤维细胞上生长的研究

    Institute of Scientific and Technical Information of China (English)

    郭宇飞; 程安春; 汪铭书; 贾仁勇; 文明; 周伟光; 陈孝跃

    2007-01-01

    对分离自鸭体的鸭病毒性肠炎病毒CH强毒株(DEV-CHv)进行了适应在鸭胚成纤维细胞(DEF)上生长的研究.结果表明,DEV-CHv病死鸭肝脏悬液以绒毛尿囊腔途径经10日龄鸭胚连续传代2次,取尿囊液接种细胞的方法可获得适应DEF生长的DEV-CHv,而肝组织内病毒直接接种在DEF上则不生长.DEV-CHv刚适应DEF时以细胞变圆、折光度增强为病变特征,而适应DEF后以细胞脱落和形成圆形蚀斑为特征.适应DEF的DEV-CHv通常30h左右使细胞脱落,36 h左右在细胞单层上形成蚀斑,48 h时细胞病变可达80%以上.

  8. Molecular Characterization of the Duck Enteritis Virus UL4 Gene

    Institute of Scientific and Technical Information of China (English)

    Hua-qi PAN; Nan WANG; Li LIU; Lei LIU; Jiang-chun HU; Pu-yan CHEN; Shu-jin WANG; Rui-bing CAO

    2009-01-01

    Duck enteritis virus (DEV) is a herpesvirus that causes an acute, contagious and fatal disease. In the present article, the DEV UL4 gene was cloned and sequenced from a vaccine virus. A degenerate oligonucleotide primer for the consensus site of herpesvirus UL3 gene and a specific primer located in UL5 were used in the polymerase chain reaction (PCR) to amplify a DNA product 2 086 bp in size. DNA sequence analysis revealed that a 714 bp open reading frame (ORF) of DEV encoding a 237 amino acid polypeptide is homologous to the family of herpesvirus UL4 proteins and therefore has been characterized as a DEV UL4 gene. Alignment of the DEV UL4 protein sequence with those of other alphaherpesviruses showed that 10 amino acid residues are completely conserved. Phylogenetic tree analysis showed that the seventeen alphaherpesviruses viruses analyzed were classified into four large groups, and the duck enteritis virus branched separately, closely related to the Mardiviruses group comprising Gallid herpesvirus 2 (GaHV-2), Gallid herpesvirus 3 (GaHV-3) and Meleagrid herpesvirus 1 (MeHV-1). The present study showed that the evolutionary relationship of the UL4 protein could be used for classification of alphaherpesviruses.

  9. Framework for automatic information extraction from research papers on nanocrystal devices

    Directory of Open Access Journals (Sweden)

    Thaer M. Dieb

    2015-09-01

    Full Text Available To support nanocrystal device development, we have been working on a computational framework to utilize information in research papers on nanocrystal devices. We developed an annotated corpus called “ NaDev” (Nanocrystal Device Development for this purpose. We also proposed an automatic information extraction system called “NaDevEx” (Nanocrystal Device Automatic Information Extraction Framework. NaDevEx aims at extracting information from research papers on nanocrystal devices using the NaDev corpus and machine-learning techniques. However, the characteristics of NaDevEx were not examined in detail. In this paper, we conduct system evaluation experiments for NaDevEx using the NaDev corpus. We discuss three main issues: system performance, compared with human annotators; the effect of paper type (synthesis or characterization on system performance; and the effects of domain knowledge features (e.g., a chemical named entity recognition system and list of names of physical quantities on system performance. We found that overall system performance was 89% in precision and 69% in recall. If we consider identification of terms that intersect with correct terms for the same information category as the correct identification, i.e., loose agreement (in many cases, we can find that appropriate head nouns such as temperature or pressure loosely match between two terms, the overall performance is 95% in precision and 74% in recall. The system performance is almost comparable with results of human annotators for information categories with rich domain knowledge information (source material. However, for other information categories, given the relatively large number of terms that exist only in one paper, recall of individual information categories is not high (39–73%; however, precision is better (75–97%. The average performance for synthesis papers is better than that for characterization papers because of the lack of training examples for

  10. A Study on the Software Quality Assurance Plan

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Tae [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    2006-07-01

    On 25 August 2006, the CMMI V1.2 (Capability Maturity Model Integration Version 1.2) was released with the new title CMMI-DEV (CMMI for Development) which supersedes the CMMI-SE/SW (CMMI for systems engineering and software engineering) V1.1. This study discusses the application of IEEE Std 730-2002, IEEE Standard for Software Quality Assurance Plans, for the implementation of the Process and Product Quality Assurance (PPQA) process area (PA) of the CMMI-DEV.

  11. Expression and characterization of the UL31 protein from duck enteritis virus

    Directory of Open Access Journals (Sweden)

    Zhu Dekang

    2009-02-01

    Full Text Available Abstract Background Previous studies indicate that the UL31 protein and its homology play similar roles in nuclear egress of all herpesviruses. However, there is no report on the UL31 gene product of DEV. In this study, we expressed and presented the basic properties of the DEV UL31 product. Results The entire ORF of the UL31 was cloned into pET 32a (+ prokaryotic expression vector. Escherichia coli BL21(DE3 competent cells were transformed with the construct followed by the induction of protein expression by the addition of IPTG. Band corresponding to the predicted sizes (55 kDa was produced on the SDS-PAGE. Over expressed 6×His-UL31 fusion protein was purified by nickel affinity chromatography. The DEV UL31 gene product has been identified by using a rabbit polyclonal antiserum raised against the purified protein. A protein of approximate 35 kDa that reacted with the antiserum was detected in immunoblots of DEV-infected cellular lysates, suggesting that the 35 kDa protein was the primary translation product of the UL31 gene. RT-PCR analyses revealed that the UL31 gene was transcribed most abundantly during the late phase of replication. Subsequently, Immunofluorescence analysis revealed that the protein was widespread speckled structures in the nuclei of infected cells. Western blotting of purified virion preparations showed that UL31 was a component of intracellular virions but was absent from mature extracellular virions. Finally, an Immunofluorescence assay was established to study the distribution of the UL31 antigen in tissues of artificially DEV infected ducks. The results showed that the UL31 antigen was primarily located in the cells of digestive organs and immunological organs. Conclusion In this work, we present the basic properties of the DEV UL31 product. The results indicate that DEV UL31 shares many similarities with its HSV or PRV homolog UL31 and suggest that functional cross-complementation is possible between members of the

  12. Adaptive Task Size Control on High Level Programming for GPU/CPU Work Sharing

    OpenAIRE

    Odajima, Tetsuya; Boku, Taisuke; Sato, Mitsuhisa; Hanawa, Toshihiro; Kodama, Yuetsu; Namyst, Raymond; Thibault, Samuel; Aumage, Olivier

    2013-01-01

    On the work sharing among GPUs and CPU cores on GPU equipped clusters, it is a critical issue to keep load balance among these heterogeneous computing resources. We have been developing a runtime system for this problem on PGAS language named XcalableMP- dev/StarPU [1]. Through the development, we found the necessity of adaptive load balancing for GPU/CPU work sharing to achieve the best performance for various application codes. In this paper, we enhance our language system XcalableMP-dev/St...

  13. Depression and Anxiety in Iranian Mothers of Children with Epilepsy

    Directory of Open Access Journals (Sweden)

    Atefeh SOLTANIFAR

    2012-03-01

    JS, Lisonkova S. Periodprevalence of epilepsy in children in BC: a population-basedstudy. Can J Neurol Sci 2009 Jan;36(1:36-41.3. Otero S. Psychopathology and psychological adjustmentin children and adolescents with epilepsy. World J Pediatr2009 Feb;5(1:12-7.4. Rodenburg HR, Stams GJJM, Meijer AM, Aldenkamp AP,Dekovic´ M. Psychopathology in children with epilepsy:a metaanalysis. J Pediatr Psychol 2005 Sep;30(6:453-68.Epub 2005 Mar 3.5. Rodenburg R, Meijer AM, Dekovic M, AldenkampAP. Family factors and psychopathology in childrenwith epilepsy: a literature review. Epilepsy Behav 2005Jun;6(4:488-503.6. Lovejoy M, Graczyk PA, O_Hare E, Neuman G. Maternaldepression and parenting behavior: a meta-analytic reviewClin Psychol Rev 2000;20:561-92.7. Shore CP, Buelow JM, Austin JK, Johnson CS.Continuing psychosocial care needs in children with newonsetepilepsy and their parents. J Neurosci Nurs 2009Oct;41(5:244-50.8. Pianta RC, Lothman DJ. Predicting behavior problemsin children with epilepsy: child factors, disease factors,family stress, and child-mother interaction. Child Dev1994 Oct;65(5:1415-28.9. Dunn DW, Austin JK, Huster GA. Symptoms ofdepression in adolescents with epilepsy. J Am Acad ChildAdolesc Psychiatr 1999;38:1133-8.10. Shore CP, Austin JK, Huster GA, Dunn DW. Identifyingrisk factors for maternal depression in families ofadolescents with epilepsy. J Specialists Pediatr Nurs2002;7:71-80.11. Yongli, Cheng-Ye ji, Jiong Qin, Zhi-Xiang Zhang.Parental anxiety and quality of Life of epileptic children.Biomed Environ Sci 2008 Jun;21(3:228-32.12. Williams J, Steel C, Sharp GB, DelosReyes E, PhillipsT, Bates S, et al. Parental anxiety and quality of life inchildren with epilepsy. Epilepsy Behav 2003;4:483-6.13. Lv R, Wu L, Jin L, Lu Q, Wang M, Qu Y, Liu H. Depression,anxiety and quality of life in parents of children withepilepsy. Acta Neurol Scand 2009 Nov;120(5:335-41.14. Baki O, Erdogan A, Kantarci O, Akisik G, KayaalpL, Yalcinkaya C. Anxiety and depression in

  14. Randomised Clinical Efficacy Trial of Topiramate and Nitrazepam in Treatment of Infantile Spasms

    Directory of Open Access Journals (Sweden)

    Razieh FALLAH

    2014-01-01

    . A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: a report of the ILEA task force on classification and terminology. Epilepsia 2001; 42(6:796–803.Riikonen RS. Favourable prognostic factors with infantile spasms. Eur J Paediatr Neurol 2010;14(1:13-18.Lagae L, Verhelst H, Ceulemans B, De Meirleir L, Nassogne MC, De Borchgrave V, et al. Treatment and long term outcome in West syndrome: the clinical reality. A multicentre follow up study. Seizure 2010;19(3:159-64.Fois A. Infantile spasms: review of the literature and personal experience. Ital J Pediatr 2010;36:15-21.Jaseja H. Justification of vigabatrin administration in West syndrome patients? Warranting a re-consideration for improvement in their quality of life. Clin Neurol Neurosurg 2009;111(2:111-14.Hwang H, Kim KJ. New antiepileptic drugs in pediatric epilepsy. Brain Dev 2008,30(9;549–55.Mikaeloff Y, de Saint-Martin A, Mancini J, Peudenier S, Pedespan JM, Vallée L, et al. Topiramate: efficacy and tolerability in children according to epilepsy syndromes. Epilepsy Res 2003;53(3:225-32.Peltzer B, Alonso WD, Porter BE. Topiramate and Adrenal-Cortico-tropic Hormone as Initial Treatment of Infantile Spasms. J Child Neurol 2009;24(4:400-5.Zou LP, Lin Q, Qin J, Cai FC, Liu ZS, Mix E. Evaluation of open-label topiramate as primary or adjunctive therapy in infantile spasms. Clin Neuropharmacol 2008;31(2:86-92.Korinthenberg R, Schreiner A. Topiramate in children with west syndrome: a retrospective multicenter evaluation of 100 patients. J Child Neurol 2007;22(3:302-6.14. Kwon YS, Jun YH, Hong YJ, Son BK. Topiramate monotherapy in infantile spasm. Yonsei Med J 2006;47(4:498-504.Hosain SA, Merchant S, Solomon GE, Chutorian A. Topiramate for the treatment of infantile spasms. J Child Neurol 2006;21(1:17-9.Glauser TA, Clark PO, McGee K. Long-term response to topiramate in patients with West syndrome. Epilepsia 2000;41(Suppl. 1:S91-4.Albsoul-Younes AM, Salem HA, Ajlouni SF, Al-Safi SA

  15. Efficacy and Safety of Intravenous Sodium Valproate in Convulsive Status Epilepticus in Children in Shahid Sadoughi Hospital

    Directory of Open Access Journals (Sweden)

    Razieh FALLAH

    2012-06-01

    Full Text Available How to Cite this Article: Fallah R, Yadegari Y, Salmani Nodushan M. Efficacy and Safety of Intravenous Sodium Valproate in Convulsive Status Epilepticus in Children in Shahid Sadoughi Hospital. Iran. J. Child. Neurol 2012;6(2:39-44. Objective Status epilepticus (SE is the most common pediatric neurologic emergency with high mortality and morbidity. There is no consensus on the drug of choice in the treatment of children. The purpose of this study was to evaluate the clinical efficacy and safety of intravenous sodium valproate as a third-line drug in the treatment of generalized convulsive SE of children. Materials & Methods In a retrospective study, medical records of those children who were admitted to Shahid Sadoughi Hospital of Yazd due to refractory generalized convulsive SE and were treated by intravenous sodium valproate as a third-line drug from 2009 to 2011 were evaluated. Results Six girls and five boys with a mean age of 5.12 ± 1.2 years (range: 3 - 9.6 years were evaluated. Intravenous valproate was effective for cessation of seizures in seven patients (63.6 %. The mean dose of valproate for stopping seizures was 27.1 ± 1.4 mg/kg/day. Children whose seizures were controlled by sodium valproate were older than non- responsive children (mean± SD: 4.8 ± 1.2 years vs. 3.1 ± 0.43 years, p= 0.03 and they also had shorter ICU stay days (mean± SD: 2.6 ± 1.4 days vs. 5.6 ± 2.8 days, p= 0.01. Two children had mild and transient nausea and vomiting. None of them had cardiopulmonary or severe paraclinical side effects. Conclusion Intravenous sodium valproate may be used as an effective and safe third-line antiepileptic drug in the treatment of pediatric generalized convulsive status epilepticus.References Raj D, Gulati S, Lodha R. Status epilepticus. Indian J Pediatr 2011;78(2:219-26. Shearer P, Riviello J. Generalized convulsive status epilepticus in adults and children: treatment guidelines and protocols. Emerg Med Clin North Am 2011

  16. Maternal rigidity in infancy and level of intelligence at school age in children born preterm

    NARCIS (Netherlands)

    Butcher, P.R.; Wijnberg-Williams, B.J; Hegemann, N; Stremmelaar, E.F; Schoemaker, M.M.; Van der Meere, J.J.; Bambang Oetomo, S

    2004-01-01

    Forty-four children who had been born preterm and their mothers participated in the follow-up study. At 3 and 14 months (corrected age) cognitive development was assessed using the BOS 2-30, the Dutch version of the Bayley Scales of Infant Development. The BOS yields measures of mental and motor dev

  17. Getting started with Hazelcast

    CERN Document Server

    Johns, Mat

    2015-01-01

    This book is a great introduction for Java developers, software architects, or DevOps looking to enable scalable and agile data within their applications. Providing in-memory object storage, cluster-wide state and messaging, or even scalable task execution, Hazelcast helps solve a number of issues that have troubled technologists for years.

  18. Language functions in preterm-born children: A systematic review and meta-analysis

    NARCIS (Netherlands)

    I.L. Van Noort-van Der Spek (Inge); M-C. Franken (Marie-Christine); N. Weisglas-Kuperus (Nynke)

    2012-01-01

    textabstractBACKGROUND AND OBJECTIVE: Preterm-born children (dev

  19. Paraneoplastic pemphigus caused by an epithelioid leiomyosarcoma and associated with fatal respiratory failure

    NARCIS (Netherlands)

    van der Waal, RIF; Pas, HH; Nousari, HC; Schulten, EAJM; Jonkman, MF; Nieboer, C; Stoof, TJ; Starink, TM; Anhalt, GJ

    2000-01-01

    A patient is described who initially presented with pemphigus vulgaris, limited to the oral cavity, and weight loss. Although the various laboratory studies pointed to the diagnosis of paraneoplastic pemphigus (PNP), the underlying neoplasm was not detected until 6 months later, when the patient dev

  20. Connexin43 confers Temozolomide resistance in human glioma cells by modulating the mitochondrial apoptosis pathway

    NARCIS (Netherlands)

    Gielen, P.R.; Aftab, Q.; Ma, N.; Chen, V.C.; Hong, X.; Lozinsky, S.; Naus, C.C.; Sin, W.C.

    2013-01-01

    Glioblastoma multiforme (GBM) is the most aggressive astrocytoma, and therapeutic options are generally limited to surgical resection, radiotherapy, and Temozolomide (TMZ) chemotherapy. TMZ is a DNA alkylating agent that causes DNA damage and induces cell death. Unfortunately, glioma cells often dev

  1. Survey of ICT and Education in Africa : Uganda Country Report

    OpenAIRE

    Farrell, Glen

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. As it adopts ICT in education, Uganda faces the same challenges as most developing economies -...

  2. Survey of ICT and Education in Africa : Lesotho Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Despite its poor ICT infrastructure and high levels of poverty, Lesotho has begun to take th...

  3. Survey of ICT and Education in Africa : Seychelles Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Seychelles is considered as one of the richest countries in Africa by income per capita. The...

  4. Survey of ICT and Education in Africa : Tanzania Country Report

    OpenAIRE

    Hare, Harry

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The past few years witnessed a host of activities aimed at injecting ICT in Tanzania's educati...

  5. Survey of ICT and Education in Africa : Rwanda Country Report

    OpenAIRE

    Farrell, Glen

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. ICT is central to Rwanda's Vision for 2020, and ICT in education is one of the core pillars ...

  6. Survey of ICT and Education in Africa : Sierra Leone Country Report

    OpenAIRE

    Mangesi, Kofi

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. As a country recovering from a devastating civil war that destroyed its infrastructure, Sier...

  7. Survey of ICT and Education in Africa : Djibouti Country Report

    OpenAIRE

    Hare, Harry

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Djibouti boasting a digital telecommunications network and connections to the rest of the wo...

  8. Survey of ICT and Education in Africa : Madagascar Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Madagascar has begun to take steps towards promoting ICTs for development with the adoption of two...

  9. Survey of ICT and Education in Africa : Senegal Country Report

    OpenAIRE

    Fall, Babacar

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Senegal's hand on commitment to incorporating ICT in education is still in the beginning sta...

  10. Survey of ICT and Education in Africa : Burundi Country Report

    OpenAIRE

    Hare, Harry

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The crisis of 1993 and the long drawn-out conflict that followed in Burundi had a devastating effe...

  11. Disease: H00841 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ated with sensorineural deafness. The same clinical presentation without deafness is also known as Fazio Lon...ou A, Vagiakou EA Infantile progressive bulbar palsy with deafness. Brain Dev 24:732-5 (2002) PMID:21110228 ...n Laere syndrome (BVVLS) is characterized by progressive pontobulbar palsy associ

  12. Survey of ICT and Education in Africa : Equatorial Guinea Country Report

    OpenAIRE

    Fall, Babacar

    2007-01-01

    This short country report, a result of a larger Information for Development Program (infoDev)-supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. In Equatorial Guinea, there is no specific policy concerning ICT, although attempts to impro...

  13. Survey of ICT and Education in Africa : Sao Tome and Príncipe Country Report

    OpenAIRE

    Fall, Babacar

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The government of Sao Tome does not consider ICT to be a priority sector, and there is curre...

  14. Survey of ICT and Education in Africa : Swaziland Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Swaziland is a small, deeply impoverished, drought-stricken country with a weak ICT infrastruc...

  15. Survey of ICT and Education in Africa : Liberia Country Report

    OpenAIRE

    Mangesi, Kofi

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Liberia is in the process of developing a comprehensive ICT policy called E-Liberia: vision ...

  16. Survey of ICT and Education in Africa : Malawi Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. A highly impoverished country, Malawi has a dedicated national ICT policy that includes the promot...

  17. Survey of ICT and Education in Africa : Mauritius Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Following the model of the Singaporean experience, the Mauritian government has been visiona...

  18. Survey of ICT and Education in Africa : Ethiopia Country Report

    OpenAIRE

    World Bank

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Leapfrogging is the word most technical people would use to describe the advancement, at least in ...

  19. Comparing Identity Management Frameworks in a Business Context

    NARCIS (Netherlands)

    Hoepman, H.J.; Joosten, H.J.M.; Siljee, J.

    2009-01-01

    Several frameworks for identity management exist, each of them with its own distinguishing features. These frameworks are complex however, and their features not easily understood. This makes it hard for businesses to understand the intricacies, and difficult to select and deploy one. This paper dev

  20. Software product lines : Organizational alternatives

    NARCIS (Netherlands)

    Bosch, J

    2001-01-01

    Software product lines enjoy increasingly wide adoption in the software industry. Most authors focus on the technical and process aspects and assume an organizational model consisting of a domain engineering unit and several application engineering units. In our cooperation with several software dev

  1. Piraatlus Guinea lahes ja Nigeerias / Eero Tepp

    Index Scriptorium Estoniae

    Tepp, Eero

    2013-01-01

    Guinea lahes lokkava piraatluse põhjused ja tegurid, mis seda soodustavad: seaduselüngad, looduslikud tingimused, ebapädev korrakaitse, poliitiline olustik, kultuuriline vastuvõetavus, majanduslik tasuvus. Sõjalised ja mittesõjalised meetmetest, mida rakendatakse piraatlusevastases võitluses

  2. Parents' Translations of Child Gesture Facilitate Word Learning in Children with Autism, Down Syndrome and Typical Development

    Science.gov (United States)

    Dimitrova, Nevena; Özçaliskan, Seyda; Adamson, Lauren B.

    2016-01-01

    Typically-developing (TD) children frequently refer to objects uniquely in gesture. Parents translate these gestures into words, facilitating children's acquisition of these words (Goldin-Meadow et al. in "Dev Sci" 10(6):778-785, 2007). We ask whether this pattern holds for children with autism (AU) and with Down syndrome (DS) who show…

  3. Cassandra high availability

    CERN Document Server

    Strickland, Robbie

    2014-01-01

    If you are a developer or DevOps engineer who understands the basics of Cassandra and are ready to take your knowledge to the next level, then this book is for you. An understanding of the essentials of Cassandra is needed.

  4. Stochastic Parameterization: Towards a new view of Weather and Climate Models

    NARCIS (Netherlands)

    Crommelin, D.T.; et al, not CWI

    2015-01-01

    The last decade has seen the success of stochastic parameterizations in short-term, medium-range and seasonal ensembles: operational weather centers now routinely use stochastic parameterization schemes to better represent model inadequacy and improve the quantification of forecast uncertainty. Dev

  5. Survey of ICT and Education in Africa : Chad Country Report

    OpenAIRE

    Fall, Babacar

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Chad and its partners in development have adopted a 10-year strategy called Education and Training...

  6. Survey of ICT and Education in Africa : Egypt Country Report

    OpenAIRE

    Hamdy, Amr

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Egypt faces significant challenges in harnessing its education system to promote its development p...

  7. Survey of ICT and Education in Africa : Morocco Country Report

    OpenAIRE

    Hamdy, Amr

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The Moroccan government has realized the key role played by ICT-based education as a positiv...

  8. Survey of ICT and Education in Africa : Comoros Country Report

    OpenAIRE

    Ngombo, Florence; Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Comoros - one of the poorest and smallest countries in the world, with a coup-prone, turbule...

  9. Does Financial Development Increase Energy Consumption? Role of Industrialization and Urbanization in Tunisia

    OpenAIRE

    Muhammad, Shahbaz; Lean, Hooi Hooi

    2011-01-01

    This paper assesses the relationship among energy consumption, financial development, economic growth, industrialization and urbanization in Tunisia from 1971-2008. The autoregressive distributed lag bounds testing approach to cointegration and Granger causality tests are employed for the analysis. The result confirms the existence of long-run relationship between energy consumption, economic growth, financial development, industrialization and urbanization in Tunisia. Moreover, financial dev...

  10. Development of novel repellents using structure-activity modeling of compounds in the USDA archival database

    Science.gov (United States)

    The United States Department of Agriculture (USDA) has developed repellents and insecticides for the U.S. military since 1942. Repellency and toxicity data for over 30,000 compounds are contained within the USDA archive. Repellency data from subsets of similarly structured compounds were used to dev...

  11. A New GIS-Nitrogen Trading Tool Concept to Minimize Reactive Nitrogen losses to the Environment

    Science.gov (United States)

    Nitrogen (N) is an essential element which is needed to maximize agricultural production and sustainability of worldwide agroecosystems. N losses to the environment are impacting water and air quality that has become an environmental concern for the future generations. It has led to the need for dev...

  12. Using complex plant pedigrees to map valuable genes

    NARCIS (Netherlands)

    Jannink, Jean-Luc; Bink, Marco C.A.M.; Jansen, Ritsert C.

    2001-01-01

    Statistical methods pioneered by human and animal geneticists use marker and pedigree information to detect quantitative trait loci within complex pedigrees. These methods, adapted to plants, promise to expand the range of data useful for identifying the genetic factors influencing plant growth, dev

  13. A Pull-in Based Test Mechanism for Device Diagnostic and Process Characterization

    NARCIS (Netherlands)

    Rocha, L.A.; Mol, L.; Cretu, E.; Wolffenbuttel, R.F.; Machado da Silva, J.

    2008-01-01

    A test technique for capacitive MEMS accelerometers and electrostatic microactuators, based on the measurement of pull-in voltages and resonance frequency, is described. Using this combination of measurements, one can estimate process-induced variations in the device layout dimensions as well as dev

  14. Cell lines and Salmonella

    NARCIS (Netherlands)

    Jonge R de; Hendriks H; Garssen J; Universteit Utrecht, afdeling; MGB; LPI

    2001-01-01

    In human gastrointestinal disease caused by Salmonella, transepithelial migration of neutrophils follows the attachment of bacteria to epithelial tissue. This migration of neutrophils is stimulated by the release of chemokines, including interleukin-8 (Il -8), from the epithelial cells. We have dev

  15. Sensory analysis of rainbow trout, oncorhynchus mykiss, fed enriched black soldier fly prepupae, hermetia illucens

    Science.gov (United States)

    A growth trial and fillet sensory analysis were conducted to examine the effects of replacing dietary fish meal with black soldier fly (BSF) prepupae, Hermetia illucens, in rainbow trout, Oncorhynchus mykiss. A practical-type trout diet was formulated to contain 45% protein; four test diets were dev...

  16. Environmental risk assessment of veterinary medicines used in Asian aquaculture

    NARCIS (Netherlands)

    Rico, A.

    2014-01-01

      One of the major constraints for the development and expansion of the Asian aquaculture industry has been the proliferation of disease outbreaks. To overcome this issue, a wide range of veterinary medicines including antibiotics, parasiticides and medical disinfectants have been recently dev

  17. The Broad Autism Phenotype Questionnaire: Mothers versus Fathers of Children with an Autism Spectrum Disorder

    Science.gov (United States)

    Seidman, Ifat; Yirmiya, Nurit; Milshtein, Shahaf; Ebstein, Richard P.; Levi, Shlomit

    2012-01-01

    Parents of individuals with autism were examined using the Broad Autism Phenotype Questionnaire (BAPQ; Hurley et al. in "J Autism Dev Disord" 37:1679-1690, 2007) assessing BAP-related personality and language characteristics. The BAPQ was administered to parents as a self-report and as an informant (spouse)-based measure. Results indicated the…

  18. CERN Computing Colloquia Spring Series: IT Security - A High-Performance Pattern Matching Engine for Intrusion Detection

    CERN Document Server

    CERN. Geneva

    2006-01-01

    The flexible and modular design of the engine allows a broad spectrum of applications, ranging from high-end enterprise level network devices that need to match hundreds of thousands of patterns at speeds of tens of gigabits per second, to low-end dev...

  19. Total performances scorecard and the sustainable development of the organizational and personal performances

    OpenAIRE

    Amalia Venera TODORUŢ

    2010-01-01

    In this paper I wanted to approach the relationship between Total Performances Scorecard and other concepts related to the continuous improvement, namely: Total Quality Management, Balanced Scorecard, Performance Management and Skills Management. Total Performances Scorecard is a holistic concept of improvement and change management. In the TPS concept, improvement, development and learning are treated as cyclic and ethical processes, through which the dev...

  20. Getting started with tmux

    CERN Document Server

    Quinn, Victor

    2014-01-01

    The book is intended for software developers, DevOps engineers, and other professionals who make heavy use of the terminal in their daily workflow. Some familiarity with the terminal is useful but no prior experience with tmux or other terminal multiplexers (such as GNU Screen) is required.

  1. Anterior fontanelle pressure monitoring in infants

    NARCIS (Netherlands)

    W.C.G. Overweg-Plandsoen

    1990-01-01

    textabstractThe objectives of this study were 1 To evaluate whether the R TT could be used as a 'fontanometer'. The literature on non-invasive ICP measurement techniques used in infants and children was studied to avoid problems already encountered by others. Subsequently, a special R TT holding dev

  2. Small-scale topology of solar atmosphere dynamics : III : granular persistence and photospheric wave amplitudes

    NARCIS (Netherlands)

    Hoekzema, N.M.; Brandt, P.N.; Rutten, R.J.

    2001-01-01

    We use a superb five-hour sequence of 900 solar images taken at La Palma to study long-duration persistence in the solar granulation,in the context of the longlived "intergranular holes" discovered by Roudier et al. (1997)and th e contention that these mark sites of convective downflow plumes.We dev

  3. 18F-FLT PET in hematologic disorders : A novel technique to analyze the bone marrow compartment

    NARCIS (Netherlands)

    Agool, Ali; Schot, Bart W.; Jager, Pieter L.; Vellenga, Edo

    2006-01-01

    Few diagnostic procedures are available to determine the degree of bone marrow cellularity and the numbers of cycling cells in patients with bone marrow disorders. Noninvasive imaging of the bone marrow compartment may be helpful. The PET tracer 3'-fluoro-3'-deoxy-L-thymidine (F-18-FLT) has been dev

  4. Housing policy socialization and de-commodification in South Korea

    NARCIS (Netherlands)

    R. Ronald; H. Lee

    2012-01-01

    South Korea has undergone significant housing system transformations in recent decades involving radical expansions in state housing provision. Growth in social forms of public housing ostensibly contradicts the neoliberal trend toward the privatization of social housing sectors elsewhere in the dev

  5. Experiment list: SRX050596 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available late embryonic stage 27506893,95.6,39.6,0 GSM694121: MCM S2 July 2010 extraction2 seq1 aliquote 1 source_name=MCM S2 July 2010 extrac...tion2_seq1 channel_1 || cell line=S2-DRSC || tissue=embryo-derived cell-line || dev

  6. Physiologically based kinetic models for the alkenylbenzene elemicin in rat and human and possible implications for risk assessment.

    NARCIS (Netherlands)

    Berg, van den S.J.; Punt, A.; Soffers, A.E.M.F.; Vervoort, J.J.M.; Ngeleja, S.; Spenkelink, B.; Rietjens, I.M.C.M.

    2012-01-01

    The present study describes physiologically based kinetic (PBK) models for the alkenylbenzene elemicin (3,4,5-trimethoxyallylbenzene) in rat and human, based on the PBK models previously developed for the structurally related alkenylbenzenes estragole, methyleugenol, and safrole. Using the newly dev

  7. Cultural tailoring for the promotion of Hepatitis B screening in Turkish Dutch: A protocol for a randomized controlled trial

    NARCIS (Netherlands)

    O. de Zwart (Onno); J.P. Mackenbach (Johan); J.H. Richardus (Jan Hendrik); Y.J.J. van der Veen (Ytje)

    2010-01-01

    textabstractBackground. Chronic hepatitis B virus infection (HBV) is an important health problem in the Turkish community in the Netherlands, and promotion of screening for HBV in this risk group is necessary. An individually tailored intervention and a culturally tailored intervention have been dev

  8. Survey of ICT and Education in Africa : Niger Country Report

    OpenAIRE

    Tutu Agyeman, Osei

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The Republic of Niger is mostly desert and it is the poorest country in the world. Subsisten...

  9. Survey of ICT and Education in Africa : Botswana Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Botswana is a small, dynamic country with visionary leadership particularly in the sector of...

  10. Survey of ICT and Education in Africa : South Africa Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. In all the different facets of the ICTs for education prism, South Africa boasts more than a...

  11. Location choice of academic entrepreneurs: Evidence from the US biotechnology industry

    NARCIS (Netherlands)

    Kolympiris, C.; Kalaitzandonakes, N.; Miller, D.

    2015-01-01

    Where knowledge-based firms are located is important because entrepreneurship, firm creation and innovation are typically associated with regional economic development, wealth creation and increased employment. In this paper we examine where academic entrepreneurs locate their firms. We begin by dev

  12. Experiment list: SRX882973 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX882973 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth...C414-009 strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=02/24/13 || de

  13. Experiment list: SRX882871 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX882871 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth...ver TC414-007 HiSeq strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=02/

  14. Experiment list: SRX879756 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX879756 mm9 No description NA Liver Liver MeSH Description=The number of offspring produced at one birth... strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=female || tissue=liver || birth_date=03/25/11 || death_da

  15. Experiment list: SRX879758 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX879758 mm9 No description NA Liver Liver MeSH Description=The number of offspring produced at one birth...train=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=09/06/10 || death_date=0

  16. Experiment list: SRX882918 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX882918 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth...C414-007 GAIIx strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=02/24/13

  17. Experiment list: SRX882974 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX882974 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth...GAIIx strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=03/20/13 || death

  18. Experiment list: SRX879757 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX879757 mm9 No description NA Liver Liver MeSH Description=The number of offspring produced at one birth...rain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=09/14/10 || death_date=08

  19. Experiment list: SRX883013 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX883013 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth...TC414-014 strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=03/20/13 || d

  20. Experiment list: SRX882884 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX882884 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth... TC414-013 HiSeq strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=03/20/

  1. Does WISC-IV Underestimate the Intelligence of Autistic Children?

    Science.gov (United States)

    Nader, Anne-Marie; Courchesne, Valérie; Dawson, Michelle; Soulières, Isabelle

    2016-01-01

    Wechsler Intelligence Scale for Children (WISC) is widely used to estimate autistic intelligence (Joseph in The neuropsychology of autism. Oxford University Press, Oxford, 2011; Goldstein et al. in "Assessment of autism spectrum disorders." Guilford Press, New York, 2008; Mottron in "J Autism Dev Disord" 34(1):19-27, 2004).…

  2. Electrical Control, Read-out and Initialization of Single Electron Spins

    NARCIS (Netherlands)

    Shafiei, M.

    2013-01-01

    An electron, in addition to its electric charge, possesses a small magnetic moment, called spin. The spin of an electron can point parallel (spin-up) or antiparallel (spin-down) to the magnetic field. These two states are analogous to zero and one of the logical bit in current digital electronic dev

  3. The Association between Teachers' Child-Centered Beliefs and Children's Academic Achievement: The Indirect Effect of Children's Behavioral Self-Regulation

    Science.gov (United States)

    Hur, Eunhye; Buettner, Cynthia K.; Jeon, Lieny

    2015-01-01

    Background: Recent studies have suggested that teachers' psychological attributes can be an indicator of teacher quality (Rimm-Kaufman and Hamre in "Dev Psychol" 45(4):958-972. doi: 10.1037/a0015861 , 2010), and teachers' child-centered beliefs have been associated with children's academic achievement (Burchinal and Cryer in "Early…

  4. Evaluation of the ADOS Revised Algorithm: The Applicability in 558 Dutch Children and Adolescents

    Science.gov (United States)

    de Bildt, Annelies; Sytema, Sjoerd; van Lang, Natasja D. J.; Minderaa, Ruud B.; van Engeland, Herman; de Jonge, Maretha V.

    2009-01-01

    The revised ADOS algorithms, proposed by Gotham et al. (J Autism Dev Disord 37:613-627, 2007), were investigated in an independent sample of 558 Dutch children (modules 1, 2 and 3). The revised algorithms lead to better balanced sensitivity and specificity for modules 2 and 3, without losing efficiency of the classification. Including the…

  5. A different development model in China’s western and eastern provinces?

    NARCIS (Netherlands)

    M.P. van Dijk (Meine Pieter)

    2011-01-01

    textabstractAbstract. Economic growth in China has declined between 2008 and 2009. The global financial crisis of 2008/9 has shown a number of structural weaknesses in the Chinese economy, such as the functioning of its capital and labor markets and the substantial income differences between the dev

  6. Financial Services and Emerging Markets

    NARCIS (Netherlands)

    B. Karreman (Bas)

    2011-01-01

    textabstractThis study addresses the organization and strategy of firms in emerging markets with an explicit application to financial services. Given the relevance of a well-functioning financial system for economic growth, understanding the organization and strategy of firms contributing to the dev

  7. Membrane contactor applications

    NARCIS (Netherlands)

    Klaassen, R.; Feron, P.H.M.; Jansen, A.

    2008-01-01

    In a membrane contactor the membrane separation is completely integrated with an extraction or absorption operation in order to exploit the benefits of both technologies fully. Membrane contactor applications that have been developed can be found in both water and gas treatment. Several recently dev

  8. Octamer-binding factor 6 (Oct-6/Pou3f1) is induced by interferon and contributes to dsRNA-mediated transcriptional responses

    NARCIS (Netherlands)

    E. Hofmann (Elisabeth); U. Reichart (Ursula); C. Gausterer (Christian); C. Guelly (Christian); D.N. Meijer (Dies); M. Müller (Martina); B. Strobl (Birgit)

    2010-01-01

    textabstractBackground: Octamer-binding factor 6 (Oct-6, Pou3f1, SCIP, Tst-1) is a transcription factor of the Pit-Oct-Unc (POU) family. POU proteins regulate key developmental processes and have been identified from a diverse range of species. Oct-6 expression is described to be confined to the dev

  9. Epidemiological analysis of data for scrapie in Great Britain

    NARCIS (Netherlands)

    Hagenaars, T.H.J.; Donnelly, C.; Ferguson, N.M.

    2006-01-01

    In recent years, the control or eradication of scrapie and any other transmissible spongiform encephalopathies (TSEs) possibly circulating in the sheep population has become a priority in Britain and elsewhere in Europe. A better understanding of the epidemiology of scrapie would greatly aid the dev

  10. The Autism Diagnostic Observation Schedule--Toddler Module: A New Module of a Standardized Diagnostic Measure for Autism Spectrum Disorders

    Science.gov (United States)

    Luyster, Rhiannon; Gotham, Katherine; Guthrie, Whitney; Coffing, Mia; Petrak, Rachel; Pierce, Karen; Bishop, Somer; Esler, Amy; Hus, Vanessa; Oti, Rosalind; Richler, Jennifer; Risi, Susan; Lord, Catherine

    2009-01-01

    The Autism Diagnostic Observation Schedule (ADOS; Lord et al., J Autism Dev Disord, 30(3):205-223, 2000) is widely accepted as a "gold standard" diagnostic instrument, but it is of restricted utility with very young children. The purpose of the current project was to modify the ADOS for use in children under 30 months of age. A modified ADOS, the…

  11. När himlen förbinds med jorden

    DEFF Research Database (Denmark)

    Dencik, Lars

    2013-01-01

    Artikeln undersøger religionens tislstædeværelse i politiken. Det skelnes mellem religion og religiositet. Udfra det analyseres og beskrives hvordan religiøsitet fremmer våldelige konflikter og får dem at gå i hårdknude....

  12. Genetics Home Reference: isolated lissencephaly sequence

    Science.gov (United States)

    ... Long-term follow-up of type 1 lissencephaly: survival is related to neuroimaging abnormalities. Dev Med Child Neurol. 2011 May;53(5):417-21. doi: 10.1111/j.1469-8749.2011.03937.x. Epub 2011 Mar 17. Citation on PubMed Images Reviewed : July 2013 ...

  13. 78 FR 77144 - Announcement of Funding Awards for Fiscal Year 2013 for the Housing Choice Voucher Program

    Science.gov (United States)

    2013-12-20

    .... NE: CENTRAL NEBRASKA JOINT HA PO BOX 509, 0 600 LOUP CITY, NE 68853. NM: AN JUAN COUNTY HA... COMM DEV... PO BOX 1630, 0 2,400 GRANTS PASS, OR 97528. OR: CENTRAL OREGON REG HA.... 405 SW 6TH ST, 0...: ALAMEDA COUNTY HA........ 22941 ATHERTON 0 30,200 ST, HAYWARD, CA 94541. CA: SANTA CRUZ COUNTY...

  14. Experiment list: SRX982082 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available elopmental stage=L3 || matching input raw data file=Input_SET4_L3_Rep1_1.fastq.gz,Input_SET4_L3_Rep1_2.fastq...0me1 SET4 L3 Rep1 ChIPSeq; Caenorhabditis elegans; ChIP-Seq source_name=whole worms || strain=MT14911 || dev

  15. GenBank blastx search result: AK243589 [KOME

    Lifescience Database Archive (English)

    Full Text Available C (devC), tRNA pseudoridine 55 synthase, CheY (cheY), 50S ribosomal protein L27, 50S ribosomal protein L21, KaiA (kaiA), KaiB (kai...B), KaiC (kaiC), glutathione peroxidase, virulence associat

  16. GenBank blastx search result: AK243355 [KOME

    Lifescience Database Archive (English)

    Full Text Available C (devC), tRNA pseudoridine 55 synthase, CheY (cheY), 50S ribosomal protein L27, 50S ribosomal protein L21, KaiA (kaiA), KaiB (kai...B), KaiC (kaiC), glutathione peroxidase, virulence associat

  17. GenBank blastx search result: AK242621 [KOME

    Lifescience Database Archive (English)

    Full Text Available C (devC), tRNA pseudoridine 55 synthase, CheY (cheY), 50S ribosomal protein L27, 50S ribosomal protein L21, KaiA (kaiA), KaiB (kai...B), KaiC (kaiC), glutathione peroxidase, virulence associat

  18. GenBank blastx search result: AK243655 [KOME

    Lifescience Database Archive (English)

    Full Text Available C (devC), tRNA pseudoridine 55 synthase, CheY (cheY), 50S ribosomal protein L27, 50S ribosomal protein L21, KaiA (kaiA), KaiB (kai...B), KaiC (kaiC), glutathione peroxidase, virulence associat

  19. GenBank blastx search result: AK242902 [KOME

    Lifescience Database Archive (English)

    Full Text Available C (devC), tRNA pseudoridine 55 synthase, CheY (cheY), 50S ribosomal protein L27, 50S ribosomal protein L21, KaiA (kaiA), KaiB (kai...B), KaiC (kaiC), glutathione peroxidase, virulence associat

  20. GenBank blastx search result: AK289194 [KOME

    Lifescience Database Archive (English)

    Full Text Available C (devC), tRNA pseudoridine 55 synthase, CheY (cheY), 50S ribosomal protein L27, 50S ribosomal protein L21, KaiA (kaiA), KaiB (kai...B), KaiC (kaiC), glutathione peroxidase, virulence associat

  1. GenBank blastx search result: AK242843 [KOME

    Lifescience Database Archive (English)

    Full Text Available C (devC), tRNA pseudoridine 55 synthase, CheY (cheY), 50S ribosomal protein L27, 50S ribosomal protein L21, KaiA (kaiA), KaiB (kai...B), KaiC (kaiC), glutathione peroxidase, virulence associat

  2. GenBank blastx search result: AK243433 [KOME

    Lifescience Database Archive (English)

    Full Text Available C (devC), tRNA pseudoridine 55 synthase, CheY (cheY), 50S ribosomal protein L27, 50S ribosomal protein L21, KaiA (kaiA), KaiB (kai...B), KaiC (kaiC), glutathione peroxidase, virulence associat

  3. GenBank blastx search result: AK288325 [KOME

    Lifescience Database Archive (English)

    Full Text Available C (devC), tRNA pseudoridine 55 synthase, CheY (cheY), 50S ribosomal protein L27, 50S ribosomal protein L21, KaiA (kaiA), KaiB (kai...B), KaiC (kaiC), glutathione peroxidase, virulence associat

  4. GenBank blastx search result: AK288021 [KOME

    Lifescience Database Archive (English)

    Full Text Available C (devC), tRNA pseudoridine 55 synthase, CheY (cheY), 50S ribosomal protein L27, 50S ribosomal protein L21, KaiA (kaiA), KaiB (kai...B), KaiC (kaiC), glutathione peroxidase, virulence associat

  5. The Autism-Spectrum Quotient and Visual Search: Shallow and Deep Autistic Endophenotypes

    Science.gov (United States)

    Gregory, B. L.; Plaisted-Grant, K. C.

    2016-01-01

    A high Autism-Spectrum Quotient (AQ) score (Baron-Cohen et al. in "J Autism Dev Disord" 31(1):5-17, 2001) is increasingly used as a proxy in empirical studies of perceptual mechanisms in autism. Several investigations have assessed perception in non-autistic people measured for AQ, claiming the same relationship exists between…

  6. Recent advances in silage microbiology

    Science.gov (United States)

    Recent advances in our understanding of silage microbiology are reviewed. The ability to extract microbial DNA from silages, amplify portions of DNA, and use the amplified regions to identify strains of microorganisms is at the core of the changes occurring recently in silage microbiology. These dev...

  7. Advancing Research on Comparative and International Education in Asia: Contribution of the "Asia Pacific Education Review"

    Science.gov (United States)

    Gok, Enes; Weidman, John C.

    2015-01-01

    This article explored the contribution of Asia Pacific Education Review (APER) to expanding the scope of research on comparative and international education in Asia. We developed a rubric based on extensive studies (Rust et al. in "Comp Educ Rev," 43(1):86-109, 1999; Foster et al. in "Int J Educ Dev" 32:711-732, 2012) of…

  8. Instant standard concept for data standards development

    NARCIS (Netherlands)

    Folmer, E.; Kulcsar, I.Z.; Roes, J.

    2013-01-01

    This paper presents the current results of an ongoing research about a new data standards development concept. The concept is called Instant Standard referring to the pressure that is generated by shrinking the length of the standardization process. Based on this concept it is estimated that the dev

  9. SCALES: A System Level Tool for Conceptual Design of Nano- and Microsatellites

    NARCIS (Netherlands)

    Aas, C.; Zandbergen, B.T.C.; Hamann, R.J.; Gill, E.K.A.

    2009-01-01

    A satellite design tool has been developed offering systems engineers a fast way to analyze the feasibility of a particular design concept. The tool differs from available tools on the market in that it is specifically targeted at small satellites in the mass range of 1-50 kg, and with a limited dev

  10. Survey of ICT and Education in Africa : Côte D’Ivoire Country Report

    OpenAIRE

    Fall, Babacar

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The development of ICT in Ivorian colleges, universities and teaching institutions is expect...

  11. Evaluation of 1066 ToxCast Chemicals in a human stem cell assay for developmental toxicity (SOT)

    Science.gov (United States)

    To increase the diversity of assays used to assess potential developmental toxicity, the ToxCast chemical library was screened in the Stemina devTOX quickPREDICT assay using human embryonic stem (hES) cells. A model for predicting teratogenicity was based on a training set of 23 ...

  12. Orchestrating Docker

    CERN Document Server

    Holla, Shrikrishna

    2015-01-01

    If you are a competent developer or DevOps with a good understanding of Linux filesystems but want to manage and orchestrate Docker services, images, and products using a multitude of techniques, then this book is for you. No prior knowledge of Docker or container virtualization is required.

  13. Farmer’s views and values to focus on cattle conservation policies: the case of eight European countries

    NARCIS (Netherlands)

    Gandini, G.; Martin-Collado, D.; Colinet, F.; Duclos, D.; Hiemstra, S.J.; Soini, K.; Diaz, C.

    2012-01-01

    Our aim was to identify elements useful in designing policies and programmes for conservation of farm animal genetic resources, taking as case study a group of European local cattle breeds. We first investigated the implications of differences among countries in the policies and programmes to be dev

  14. Measuring correlated electronic and vibrational spectral dynamics using line shapes in two-dimensional electronic-vibrational spectroscopy.

    Science.gov (United States)

    Lewis, Nicholas H C; Dong, Hui; Oliver, Thomas A A; Fleming, Graham R

    2015-05-01

    Two-dimensional electronic-vibrational (2DEV) spectroscopy is an experimental technique that shows great promise in its ability to provide detailed information concerning the interactions between the electronic and vibrational degrees of freedom in molecular systems. The physical quantities 2DEV is particularly suited for measuring have not yet been fully determined, nor how these effects manifest in the spectra. In this work, we investigate the use of the center line slope of a peak in a 2DEV spectrum as a measure of both the dynamic and static correlations between the electronic and vibrational states of a dye molecule in solution. We show how this center line slope is directly related to the solvation correlation function for the vibrational degrees of freedom. We also demonstrate how the strength with which the vibration on the electronic excited state couples to its bath can be extracted from a set of 2DEV spectra. These analytical techniques are then applied to experimental data from the laser dye 3,3'-diethylthiatricarbocyanine iodide in deuterated chloroform, where we determine the lifetime of the correlation between the electronic transition frequency and the transition frequency for the backbone C = C stretch mode to be ∼1.7 ps. Furthermore, we find that on the electronic excited state, this mode couples to the bath ∼1.5 times more strongly than on the electronic ground state. PMID:25956093

  15. Microbial detection and monitoring in advanced life support systems like the International Space Station

    NARCIS (Netherlands)

    van Tongeren, Sandra P.; Krooneman, Janneke; Raangs, Gerwin C.; Welling, Gjalt W.; Harmsen, Hermie J. M.

    2006-01-01

    Potentially pathogenic microbes and so-called technophiles may form a serious threat in advanced life support systems, such as the International Space Station (ISS). They not only pose a threat to the health of the crew, but also to the technical equipment and materials of the space station. The dev

  16. Microbial detection and monitoring in advanced life support systems like the international space station

    NARCIS (Netherlands)

    van Tongeren, Sandra P.; Krooneman, Janneke; Raangs, Gerwin C.; Welling, Gjalt W.; Harmsen, Hermie J. M.

    2007-01-01

    Potentially pathogenic microbes and so-called technophiles may form a serious threat in advanced life support systems, such as the International Space Station (ISS). They not only pose a threat to the health of the crew, but also to the technical equipment and materials of the space station. The dev

  17. Autism and Dimensionality: Differences between Copying and Drawing Tasks

    Science.gov (United States)

    Sheppard, Elizabeth; Ropar, Danielle; Mitchell, Peter

    2009-01-01

    Previous research suggests individuals with autism may be less influenced by a three-dimensional interpretation when copying line drawings (Sheppard et al. "J Autism Dev Disord" 37:1913-1924, 2007). The current research aimed to determine whether this reduced dimensionality effect extends to drawings of an actual object. Twenty-four children and…

  18. The Autism Diagnostic Observation Schedule, Module 4: Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (N = 93)

    Science.gov (United States)

    de Bildt, Annelies; Sytema, Sjoerd; Meffert, Harma; Bastiaansen, Jojanneke A. C. J.

    2016-01-01

    This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in "J Autism Dev Disord" 44(8):1996-2012, 2014) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the revised algorithm ASD cut-off…

  19. The large radius human centrifuge 'A human hypergravity habitat, H

    NARCIS (Netherlands)

    Loon, J.J.W.A. van; Wuyts, F.; Bäcker, N.; Berte, J.; Bok, K.; Bos, J.; Groen, E.; Boyle, R.; Bravenoer, N.; Eekhoff, M.; Chouker, A.; Clement, G.; Cras, P.; Denise, P.; Felsenberg, D.; Fong, K.; Fuller, C.; Heer, M.; Hinghofer-Szalkay, H.; Iwase, S.; Karemaker, J.M.; Linnarsson, D.; Lüthen, C.; Mulder, E.; Narici, M.; Norsk, P.; Paloski, W.; Rutten, M.; Saggini, R.; Stephan, A.; Ullrich, O.; Vautmans, L.; Young, L.

    2009-01-01

    Over the last decades a significant body of knowledge has been gained on the adaptation of the human body going into near weightlessness conditions as well as for the re-adaptation to 1xg Earth conditions after an orbital space flight. Ground-based paradigms for microgravity simulation have been dev

  20. Improving adolescent sexual and reproductive health in Latin America: reflections from an International Congress

    NARCIS (Netherlands)

    K. Córdova Pozo; V. Chandra-Mouli; P. Decat; E. Nelson; S. de Meyer; L. Jaruseviciene; B. Vega; Z. Segura; N. Auquilla; A. Hagens; D. van Braeckel; K. Michielsen

    2015-01-01

    In February 2014, an international congress on Promoting Adolescent Sexual and Reproductive Health (ASRH) took place in Cuenca, Ecuador. Its objective was to share evidence on effective ASRH intervention projects and programs in Latin America, and to link this evidence to ASRH policy and program dev

  1. Perceived Social Competence and Loneliness among Young Children with ASD: Child, Parent and Teacher Reports

    Science.gov (United States)

    Zeedyk, Sasha M.; Cohen, Shana R.; Eisenhower, Abbey; Blacher, Jan

    2016-01-01

    Perceived loneliness and social competence were assessed for 127 children with ASD without comorbid ID, 4-7 years old, through child self-report. Using an abbreviated version of the "Loneliness and Social Dissatisfaction Questionnaire" (LSDQ; Cassidy and Asher in Child Dev 63:250-365, 1992), the majority of children reported friendships,…

  2. Improving component interoperability and reusability with the java connection framework (JCF): overview and application to the ages-w environmental model

    Science.gov (United States)

    Environmental modeling framework (EMF) design goals are multi-dimensional and often include many aspects of general software framework development. Many functional capabilities offered by current EMFs are closely related to interoperability and reuse aspects. For example, an EMF needs to support dev...

  3. Retrofit of Ressalat jacket platform (Persian Gulf) using friction damper device

    DEFF Research Database (Denmark)

    Komachi, Y.; Tabeshpour, M. R.; Golafshani, A. A.;

    2011-01-01

    A friction damper device (FDD) is used for vibration control of an existing steel jacket platform under seismic excitation. First, the damping is presented for vibration mitigation of structures located in seismically active zones. A new method for quick design of friction or yielding damping dev...

  4. Development of a robot Holon using an open modular controller

    DEFF Research Database (Denmark)

    Schnell, Jakob; Andersen, Søren; Sørensen, Christian;

    1999-01-01

    Holonic Manufacturing Systems (HMS) has during the last period presented itself as an advantageous theoretical foundation for the problems that arise in controlling agile manufacturing systems. Previous research, at the Department, has demonstrated how modern shop floor control systems can be dev...

  5. Kuidas taasluua minevikku / David Vseviov

    Index Scriptorium Estoniae

    Vseviov, David, 1949-

    2012-01-01

    Mineviku kirjeldamisega seoses peab silmas pidama sellega kaasnevat ettemääratud piiratust. Ajaloolise tõe väide saab olla pädev vaid kõige üldisemates raamides, jättes detailides vabaduse kõikvõimalikeks oletusteks

  6. Metamorphic history of the Central Pyrenees Part II, Valle de Arán, Sheet 4

    NARCIS (Netherlands)

    Zwart, H.J.

    1963-01-01

    The structural geology and metamorphic petrology of the Bosost area in the Valle de Arán (Central Pyrenees) is discussed. The rocks exposed in this area consist of Cambro-Ordovician mica-schists with numerous granite and pegmatite bodies, phyllites and limestones; Silurian slates and schists and Dev

  7. Assessment of the effective dose in supine, prone, and oblique positions in the maxillofacial region using a novel combined extremity and maxillofacial cone beam computed tomography scanner

    NARCIS (Netherlands)

    J. Koivisto; J. Wolff; J. Järnstedt; P. Dastidar; M. Kortesniemi

    2014-01-01

    Objective The objectives of this study were to assess the organ and effective doses (International Commission on Radiological Protection [ICRP] 103 standard) resulting from supine, prone, and oblique phantom positions in the maxillofacial region using a novel cone beam computed tomography (CBCT) dev

  8. Data of evolutionary structure change: 1ACPA-2DEVC [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ACPA-2DEVC 1ACP 2DEV A C STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDT...HHH EEE EEEEEEE EEEEEEEEEE -------- 0 1ACP... A 1ACPA EEAEK-----IT...> ARG CA 219 LYS CA 147 THR CA 173 1ACP... A 1ACPA ELVMALEEEFDT

  9. Data of evolutionary structure change: 1ACPA-2DEVB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ACPA-2DEVB 1ACP 2DEV A B STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDT...H EEE EEEEEEE EEEEEEEEEE ------- 0 1ACP... A 1ACPA KITTV-----QAAID...> ILE CA 301 1ACP A 1ACP...ine>THR CA 171 1ACP

  10. Automatic discrimination between laughter and speech

    NARCIS (Netherlands)

    Truong, K.; Leeuwen, D. van

    2007-01-01

    Emotions can be recognized by audible paralinguistic cues in speech. By detecting these paralinguistic cues that can consist of laughter, a trembling voice, coughs, changes in the intonation contour etc., information about the speaker’s state and emotion can be revealed. This paper describes the dev

  11. Experiment list: SRX1428007 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available .7,0 ChIP Tfap2c in Mus musculus: TSC breed=not applicable || cultivar=not applicable || ecotype=not applicable... || isolate=not applicable || strain=not applicable || age=not applicable || dev_stage=not applicable ||

  12. Experiment list: SRX1428006 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 6,0 ChIP input control in Mus musculus: TSC breed=not applicable || cultivar=not applicable || ecotype=not applicable... || isolate=not applicable || strain=not applicable || age=not applicable || dev_stage=not applicable

  13. Experiment list: SRX1428005 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 1.3,0 ChIP Tfap2c in Mus musculus: 24 diff TSC breed=not applicable || cultivar=not applicable || ecotype=not applicable... || isolate=not applicable || strain=not applicable || age=not applicable || dev_stage=not applicable

  14. Experiment list: SRX1428009 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 39.7,7042 ChIP Elf5 in Mus musculus: f TSC breed=not applicable || cultivar=not applicable || ecotype=not applicable... || isolate=not applicable || strain=not applicable || age=not applicable || dev_stage=not applicable

  15. Characterization of African Bush Mango trees with emphasis on the differences between sweet and bitter trees in the Dahomey Gap (West Africa)

    NARCIS (Netherlands)

    Vihotogbe, R.

    2012-01-01

     African bush mango trees (ABMTs) are economically the most important species within the family of Irvingiaceae. They are priority trees producing non-timber forest products (NTFPs) and widely distributed in the humid lowland forests of West and Central Africa. To boost their production and dev

  16. Long-term salinity development in a lysimeter experiment.

    NARCIS (Netherlands)

    Hoorn, van J.W.; Katerji, N.; Hamdy, A.

    1997-01-01

    Over a period of 6 years, various crops were grown in tanks, filled with loam and clay, and were irrigated with water of three different levels of salinity. A combination of soil water sampling, salt balance and salt model was used to study the change in the composition of the soil water and the dev

  17. Cooperation between information system development and operations: a literature review

    NARCIS (Netherlands)

    Erich, Floris; Amrit, Chintan; Daneva, Maya

    2014-01-01

    Software development can profit from improvements in the deployment and maintenance phases. DevOps improves these phases through a collection of principles and practices, centered around close collaboration between Development and Operations personnel. Both sides have paid little attention to issues

  18. On the Integration of Automatic Deployment into the ABS Modeling Language

    NARCIS (Netherlands)

    Gouw, C.P.T. de; Lienhardt, M.; Mauro, J.; Nobakht, B.; Zavattaro, G.; Dustdar, S.; Leymann, F.; Villari, M.

    2015-01-01

    In modern software systems, deployment is an integral and critical part of application development (see, e.g., the DevOps approach to software development). Nevertheless, deployment is usually overlooked at the modeling level, thus losing the possibility to perform deployment conscious decisions dur

  19. Inclusive business through partnerships

    NARCIS (Netherlands)

    R.J.M. van Tulder (Rob); A. Da Rosa (Andrea)

    2011-01-01

    textabstractAcademic and policy thought on economic growth and sustainable development in the 21st century represents a breach with traditional thinking. Traditional development approaches are getting replaced by new and more modern development thinking that adopts a contingency approach towards dev

  20. Performance Measurement in Property Management

    OpenAIRE

    Aho, Johannes

    2016-01-01

    This research examines the performance measurement of processes in property management and maintenance context. The purpose was to first, develop a framework which divides processes into modes of operation that share managerial similarities. Second, apply this framework in property management performance measurement. Constructive approach was used as the scientific research approach. An extensive literature review was first conducted after which the framework was dev...

  1. Autism Diagnostic Interview-Revised (ADI-R) Algorithms for Toddlers and Young Preschoolers : Application in a Non-US Sample of 1,104 Children

    NARCIS (Netherlands)

    de Bildt, Annelies; Sytema, Sjoerd; Zander, Eric; Bölte, Sven; Sturm, Harald; Yirmiya, Nurit; Yaari, Maya; Charman, Tony; Salomone, Erica; LeCouteur, Ann; Green, Jonathan; Bedia, Ricardo Canal; Primo, Patricia García; van Daalen, Emma; de Jonge, Maretha V.; Guðmundsdóttir, Emilía; Jóhannsdóttir, Sigurrós; Raleva, Marija; Boskovska, Meri; Rogé, Bernadette; Baduel, Sophie; Moilanen, Irma; Yliherva, Anneli; Buitelaar, Jan; Oosterling, Iris J.

    2015-01-01

    The current study aimed to investigate the Autism Diagnostic Interview-Revised (ADI-R) algorithms for toddlers and young preschoolers (Kim and Lord, J Autism Dev Disord 42(1):82–93, 2012) in a non-US sample from ten sites in nine countries (n = 1,104). The construct validity indicated a good fit of

  2. Autism Diagnostic Interview-Revised (ADI-R) Algorithms for Toddlers and Young Preschoolers: Application in a Non-US Sample of 1,104 Children

    NARCIS (Netherlands)

    Bildt, A. de; Sytema, S.; Zander, E.; Bolte, S.; Sturm, H.; Yirmiya, N.; Yaari, M.; Charman, T.; Salomone, E.; LeCouteur, A.; Green, J.; Bedia, R.C.; Primo, P.G.; Daalen, E. van; Jonge, M.V. de; Guethmundsdottir, E.; Johannsdottir, S.; Raleva, M.; Boskovska, M.; Roge, B.; Baduel, S.; Moilanen, I.; Yliherva, A.; Buitelaar, J.; Oosterling, I.J.

    2015-01-01

    The current study aimed to investigate the Autism Diagnostic Interview-Revised (ADI-R) algorithms for toddlers and young preschoolers (Kim and Lord, J Autism Dev Disord 42(1):82-93, 2012) in a non-US sample from ten sites in nine countries (n = 1,104). The construct validity indicated a good fit of

  3. Autism Diagnostic Interview-Revised (ADI-R) Algorithms for Toddlers and Young Preschoolers : Application in a Non-US Sample of 1,104 Children

    NARCIS (Netherlands)

    de Bildt, Annelies; Sytema, Sjoerd; Zander, Eric; Bolte, Sven; Sturm, Harald; Yirmiya, Nurit; Yaari, Maya; Charman, Tony; Salomone, Erica; LeCouteur, Ann; Green, Jonathan; Canal Bedia, Ricardo; Primo, Patricia Garcia; van Daalen, Emma; de Jonge, Maretha V.; Gudmundsdottir, Emilia; Johannsdottir, Sigurros; Raleva, Marija; Boskovska, Meri; Roge, Bernadette; Baduel, Sophie; Moilanen, Irma; Yliherva, Anneli; Buitelaar, Jan; Oosterling, Iris J.

    2015-01-01

    The current study aimed to investigate the Autism Diagnostic Interview-Revised (ADI-R) algorithms for toddlers and young preschoolers (Kim and Lord, J Autism Dev Disord 42(1):82-93, 2012) in a non-US sample from ten sites in nine countries (n = 1,104). The construct validity indicated a good fit of

  4. Electroacoustic Music Is a "Subversion" to the Form of Traditional Music——An Idea From "Etudes Metro"—the Work of Pierre

    Institute of Scientific and Technical Information of China (English)

    Muyan Li

    2011-01-01

    We have studied"Metro Etudes"—the work of Pierre Schaeffer in this paper, and exploited the proposal of the concept of "concrete music". We discuss the basic concepts and characteristics of the current electroacoustic musics profoundly, analysis their dev

  5. Literatuuronderzoek voertuigkering H4-niveau : een literatuurstudie naar voertuigkeringen beproefd op H4-niveau volgens prEN 1317-1 en prEN 1317-2. In opdracht van Bouwdienst Rijkswaterstaat, Apeldoorn.

    NARCIS (Netherlands)

    Pol, W.H.M. van de

    1997-01-01

    Not many full-scale tests at the H4 level have yet been carried out according to the first and second standards of the prEN 1317. For this reason, only a few H4 tests are mentioned in the literature. Full-scale tests conducted with heavy vehicles are also mentioned in the literature. These tests dev

  6. Bicycle Rider Control: Observations, Modeling & Experiments

    NARCIS (Netherlands)

    Kooijman, J.D.G.

    2012-01-01

    Bicycle designers traditionally develop bicycles based on experience and trial and error. Adopting modern engineering tools to model bicycle and rider dynamics and control is another method for developing bicycles. This method has the potential to evaluate the complete design space, and thereby dev

  7. Assessing Longitudinal Change: Adjustment for Regression to the Mean Effects

    Science.gov (United States)

    Rocconi, Louis M.; Ethington, Corinna A.

    2009-01-01

    Pascarella (J Coll Stud Dev 47:508-520, 2006) has called for an increase in use of longitudinal data with pretest-posttest design when studying effects on college students. However, such designs that use multiple measures to document change are vulnerable to an important threat to internal validity, regression to the mean. Herein, we discuss a…

  8. Nanowire-based gas sensors

    NARCIS (Netherlands)

    Chen, X.; Wong, C.K.Y.; Yuan, C.A.; Zhang, G.

    2013-01-01

    Gas sensors fabricated with nanowires as the detecting elements are powerful due to their many improved characteristics such as high surface-to-volume ratios, ultrasensitivity, higher selectivity, low power consumption, and fast response. This paper gives an overview on the recent process of the dev

  9. Küünlavalgus soojendab hinge / Kadri Tramm

    Index Scriptorium Estoniae

    Tramm, Kadri

    2014-01-01

    Erivärvilised ja -kujulised küünlad annavad hubast valgust ja on ka pilkupüüdev sisekujunduselement. Nõu annavad Kaubamaja Kodumaailma teenindusjuht Aires Rühka ja Scheteligi hulgimüügi esindaja Janika Paat

  10. Stimuli responsive polymer/quantum dot hybrid platforms modified at the nanoscale

    OpenAIRE

    Tagit, Oya

    2010-01-01

    Quantum dots, QDs, receive growing attention from many research disciplines owing to their advantages as fluorescent probes including their nanoscale size (similar to biomolecules), high quantum yield and molar extinction coefficients, versatility in surface modification, broad excitation spectra (for multicolor imaging) and narrow band emission and tunable optical properties. Fabricating QD/polymer hybrid nanostructures enables realization of many potential applications as optoelectronic dev...

  11. Attenuated Salmonella typhimurium delivering DNA vaccine encoding duck enteritis virus UL24 induced systemic and mucosal immune responses and conferred good protection against challenge

    Directory of Open Access Journals (Sweden)

    Yu Xia

    2012-07-01

    Full Text Available Abstract Orally delivered DNA vaccines against duck enteritis virus (DEV were developed using live attenuated Salmonella typhimurium (SL7207 as a carrier and Escherichia coli heat labile enterotoxin B subunit (LTB as a mucosal adjuvant. DNA vaccine plasmids pVAX-UL24 and pVAX-LTB-UL24 were constructed and transformed into attenuated Salmonella typhimurium SL7207 resulting SL7207 (pVAX-UL24 and SL7207 (pVAX-LTB-UL24 respectively. After ducklings were orally inoculated with SL7207 (pVAX-UL24 or SL7207 (pVAX-LTB-UL24, the anti-DEV mucosal and systemic immune responses were recorded. To identify the optimum dose that confers maximum protection, we used different doses of the candidate vaccine SL7207 (pVAX-LTB-UL24 during oral immunization. The strongest mucosal and systemic immune responses developed in the SL7207 (pVAX-LTB-UL24 (1011 CFU immunized group. Accordingly, oral immunization of ducklings with SL7207 (pVAX-LTB-UL24 showed superior efficacy of protection (60-80% against a lethal DEV challenge (1000 LD50, compared with the limited survival rate (40% of ducklings immunized with SL7207 (pVAX-UL24. Our study suggests that the SL7207 (pVAX-LTB-UL24 can be a candidate DEV vaccine.

  12. Asymmetry and infants born preterm

    NARCIS (Netherlands)

    Nuijsink, J.

    2012-01-01

    The main aim of the thesis was to contribute to the diagnostic process and clinical decision making by pediatric physiotherapists in very young infants with an atypical motor performance, influenced by both an asymmetric development, and a development according to a preterm birth. In Part I, the dev

  13. A Feminist Political Economic Analysis of the US Chicken Industry

    OpenAIRE

    Kristin Sampson

    2008-01-01

    Kristin Sampson gives an overview of competing poultry production systems from a feminist political economic analysis. She considers three characteristics of the US industry, identified as key drivers of the industry's success: structural organization, production and processing technologies and responsiveness to consumer demands. Development (2008) 51, 547–554. doi:10.1057/dev.2008.59

  14. The European Romani Women's Movement: The struggle for human rights

    OpenAIRE

    Rita Izsák

    2009-01-01

    Rita Izsák discusses the International Romani Women's Network (IRWN), the first registered international umbrella organization representing Romani women of all European Romani groups. She examines how IRWN is promoting women's rights, and the connection between mainstream feminist movements and the Romani movement. Development (2009) 52, 200–207. doi:10.1057/dev.2009.9

  15. How to Manufacture a Global Food Crisis

    OpenAIRE

    Walden Bello

    2008-01-01

    Reviewing the policies of the World Bank, the International Monetary Fund and the World Trade Organization, Walden Bello examines how ‘free trade’ is destroying Third World agriculture – and who's fighting back. Development (2008) 51, 450–455. doi:10.1057/dev.2008.60

  16. Handshake, No. 5 (April 2012)

    OpenAIRE

    International Finance Corporation

    2012-01-01

    This issue includes the following headings: seeds and soil: smallholder agriculture; innovation: pairing commercial buyers with rural producers; grain storage: a ready role for public-private partnerships (PPPs); agricultural clusters: powering Africas agricultural potential; and interviews: AgDevCo, bill and Melinda gates foundation, earth policy institute.

  17. Re-Evaluation of Constant versus Varied Punishers Using Empirically Derived Consequences

    Science.gov (United States)

    Toole, Lisa M.; DeLeon, Iser G.; Kahng, Sung Woo; Ruffin, Geri E.; Pletcher, Carrie A.; Bowman, Lynn G.

    2004-01-01

    Charlop, Burgio, Iwata, and Ivancic [J. Appl. Behav. Anal. 21 (1988) 89] demonstrated that varied punishment procedures produced greater or more consistent reductions of problem behavior than a constant punishment procedure. More recently, Fisher and colleagues [Res. Dev. Disabil. 15 (1994) 133; J. Appl. Behav. Anal. 27 (1994) 447] developed a…

  18. Linking theories of change and observed reality: the Shea value chain partnership case in Burkina

    NARCIS (Netherlands)

    Drost, S.; Wijk, van J.; Vellema, S.

    2012-01-01

    This case study found out how a public-private partnership in Burkina Faso helped female shea nut producers to link up with the cosmetic industry. Empirical data collected from October-December 2011 revealed that the shea value chain partnership between a international shea processing company, a dev

  19. The Relationship between Sensory Sensitivity and Autistic Traits in the General Population

    Science.gov (United States)

    Robertson, Ashley E.; Simmons, David R.

    2013-01-01

    Individuals with Autism Spectrum Disorders (ASDs) tend to have sensory processing difficulties (Baranek et al. in J Child Psychol Psychiatry 47:591-601, 2006). These difficulties include over- and under-responsiveness to sensory stimuli, and problems modulating sensory input (Ben-Sasson et al. in J Autism Dev Disorders 39:1-11, 2009). As those…

  20. Reassessing the validity of research assessments. A social experiment

    NARCIS (Netherlands)

    P.H.J. Achterberg (Peter)

    2010-01-01

    textabstractThe literature concerned with bibliometry and scientometry has been concerned with the question of how the actual output and impact of scholars can be ascertained. Whereas a situation in which scholars were mainly judged of subjective criteria was deemed undesirable, scientometry has dev

  1. Measuring Meaningful Outcomes in Consequential Contexts: Searching for a Happy Medium in Educational Technology Research (Phase II)

    Science.gov (United States)

    Ross, Steven M.; Morrison, Jennifer R.

    2014-01-01

    In a paper published 25 years ago, Ross and Morrison ("Educ Technol Res Dev" 37(1):19-33, 1989) called for a "happy medium" in educational technology research, to be achieved by balancing high rigor of studies (internal validity) with relevance to real-world applications (external validity). In this paper, we argue that,…

  2. High Flyers: Policies and Strategies that Boost Developmental Education Success in Florida's Community Colleges

    Science.gov (United States)

    Ajose, Lande; Bhatt, Ria Sengupta; Kaur, Gagandeep

    2011-01-01

    In 2010, Jobs for the Future (JFF) contracted BTW "informing change" (BTW) to conduct a study on developmental education (DevEd) practices and policies in the state of Florida. This study was undertaken with two purposes. First, JFF wanted to see what common threads could be identified among the strategies and approaches of community colleges that…

  3. Developing Linux kernel space device driver

    Institute of Scientific and Technical Information of China (English)

    Zheng Wei; Wang Qinruo; Wu Naiyou

    2003-01-01

    This thesis introduces how to develop kernel level device drivers on Linux platform in detail. On the basis of comparing proc file system with dev file system, we choose PCI devices and USB devices as instances to introduce the method of writing device drivers for character devices by using these two file systems.

  4. Survey of ICT and Education in Africa : Cape Verde Country Report

    OpenAIRE

    Tutu, Osei Agyeman

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Cape Verde has made significant strides in the implementation of ICTs in education. The drawback o...

  5. Experiment list: SRX444197 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ay || age=24 || body_site=Skin, arm || phenotype=Caucasian || cell_type=Dermal fibroblast || culture_collect...ion=NCSCR || dev_stage=Adult || sex=Male || tissue_type=Skin || label=AD04DF_LMNA

  6. A Parent-Mediated Intervention that Targets Responsive Parental Behaviors Increases Attachment Behaviors in Children with ASD: Results from a Randomized Clinical Trial

    Science.gov (United States)

    Siller, Michael; Swanson, Meghan; Gerber, Alan; Hutman, Ted; Sigman, Marian

    2014-01-01

    The current study is a randomized clinical trial evaluating the efficacy of Focused Playtime Intervention (FPI) in a sample of 70 children with Autism Spectrum Disorder. This parent-mediated intervention has previously been shown to significantly increase responsive parental communication (Siller et al. in "J Autism Dev Disord"…

  7. Appi - tarbijast võlgnik kolis välismaale! : kommentaar Riigikohtu lahenditele asjades 3-2-1-114-12 ja 3-2-1-123-12 / Karin Sein

    Index Scriptorium Estoniae

    Sein, Karin, 1974-

    2013-01-01

    Riigikohtu lahendist 3-2-1-114-12, milles vaieldi füüsilisest isikust võlgniku pankroti väljakuulutamise kohtualluvuse üle. Lahendist 3-2-1-123-12, milles vaieldi, kas ja millistel tingimustel on Eesti kohus pädev läbi vaatama hagi Eestist lahkunud tarbijast krediidisaaja vastu

  8. MEANING : a roadmap to knowledge technologies

    NARCIS (Netherlands)

    Rigau, G.; Magnini, B.; Agirre, E.; Vossen, P.; Carroll, J.

    2002-01-01

    Knowledge Technologies need to extract knowledge from existing texts, which calls for advanced Human Language Technologies (HLT). Progress is being made in Natural Language Processing but there is still a long way towards Natural Language Understanding. An important step towards this goal is the dev

  9. Low-loss and programmable integrated photonic beamformer for electronically-steered broadband phased array antennas

    NARCIS (Netherlands)

    Zhuang, Leimeng; Marpaung, David; Burla, Maurizio; Roeloffzen, Chris; Beeker, Willem; Leinse, Arne; Dijk, van Paul

    2011-01-01

    Recently we have reported the dev electronically-steered Ku-band (10.7-12.75 G antenna system employing an integrated photonic beamformer, which is intended to be applied on high-speed transport vehicles for mobile reception of digital video broadcasting via satellite signals (1). Besides the advant

  10. A case study of Pedagogical Content Knowledge and faculty development in the Philippines

    NARCIS (Netherlands)

    E. van den Berg

    2010-01-01

    The Science Teacher Education Project Southern Philippines (STEPS, 1996-2004) aimed at establishing a science and mathematics education centre and viable teacher education programmes. The most crucial component was faculty development. This involved the selection of faculty and then professional dev

  11. Student Perceptions of Effective Instruction and the Development of Critical Thinking: A Replication and Extension

    Science.gov (United States)

    Loes, Chad N.; Salisbury, Mark H.; Pascarella, Ernest T.

    2015-01-01

    This study utilized data from the Wabash National Study of Liberal Arts Education to test the robustness of research conducted by Pascarella et al. ("J Coll Stud Dev" 37:7-19, 1996) that explored the relationship between student perceptions of exposure to organized and clear instruction and growth in critical thinking skills among…

  12. Non-diffractive optically variable security devices

    NARCIS (Netherlands)

    Renesse, R.L. van

    1991-01-01

    At the past optical security conferences attention was focused on diffractive structures, e.g. holograms, embossed gratings and thin—film devices, as security elements on valuable documents. The main reasons for this emphasis are, that the iridescent effect of such diffractive optically variable dev

  13. ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) DRINKING WATER SYSTEMS CENTER TECHNOLOGY SPECIFIC TEST PLAN: REMOVAL OF MICROBIOLOGICL AND PARTICULATE CONTAMINANTS BY MEMBRANE FILTRATION

    Science.gov (United States)

    This document is the Environmental technology Verification (ETV) Technology Specific test Plan (TSTP) for evaluation of water treatment equipment for removal of microbiological and particulate contaminants using membrane filtration. This TSTP is to be used as a guide in the dev...

  14. The articulation of transnational campaigns

    DEFF Research Database (Denmark)

    Strange, Michael Stewart

    2011-01-01

    The article traces the complex series of relations that are constitutive of transnational campaigning through empirical research, focusing on political campaigning critical of the WTO's General Agreement on Trade-in-Services. Applying the methodology of post-structuralist discourse theory, as dev...

  15. DMPD: Pathways connecting inflammation and cancer. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 18325755 Pathways connecting inflammation and cancer. Allavena P, Garlanda C, Borre...llo MG, Sica A, Mantovani A. Curr Opin Genet Dev. 2008 Feb;18(1):3-10. Epub 2008 Mar 5. (.png) (.svg) (.html) (.csml) Show Pathways... connecting inflammation and cancer. PubmedID 18325755 Title Pathways connecting infl

  16. Brief Report: No Association between Premorbid Adjustment in Adult-Onset Schizophrenia and Genetic Variation in Dysbindin

    Science.gov (United States)

    Schirmbeck, Frederike; Georgi, Alexander; Strohmaier, Jana; Schmael, Christine; Boesshenz, Katja V.; Muhleisen, Thomas W.; Herms, Stefan; Hoffmann, Per; Jamra, Rami Abou; Schumacher, Johannes; Maier, Wolfgang; Propping, Peter; Nothen, Markus M.; Cichon, Sven; Rietschel, Marcella; Schulze, Thomas G.

    2008-01-01

    Whereas "Dysbindin" is considered a schizophrenia vulnerability gene, there is no consistency of findings. Phenotype refinement approaches may help to increase the genetic homogeneity and thus reconcile conflicting results. Premorbid adjustment (PMA) has been suggested to aid the phenotypic dissection. Gornick et al. ("J Autism Dev Disord"…

  17. EXPRESSION OF EPIDERMAL GROWTH FACTOR, TRANSFORMING GROWTH FACTOR-a AND THEIR RECEPTOR IN HUMAN PITUITARY TUMORS

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Long

    2001-01-01

    [1]LIU Xu-wen, FU Pei-yu, GAO Zhi-xian. Expression of epidermal growth factor receptors in human glioma [J]. Chin J Neurosurgery 1998; 14:71.[2]Wong AJ, Ruppert JM, Bigner SH, et al. Structural alterations of the epidermal growth factor receptor gene in human gliomas [J]. Proc Natl Acad Sci USA 1992; 89:4309.[3]Webster J, Ham J, Bevan JS. Preliminary characterization of growth factors secreted by human pituitary tumors [J]. J Clin Endocrinol Metab 1991; 72:687.[4]Klibanski A. Nonsecreting pituitary tumors [J]. Endocrinol Metab Clin North Am 1987; 16:793.[5]LeRiche VK, Asa SL, Ezzat S. Epidermal growth factor and its receptor (EGF-R) in human pituitary adenomas: EGF-R correlates with tumor aggressiveness [J]. J Clin Endocrinol Metab 1996; 81:656.

  18. Animal, animalité, devenir-animal

    OpenAIRE

    Viennet, Denis

    2011-01-01

    Question de regard Nous regardons les animaux et les animaux nous regardent. Nous faisons signe à un chat, par la voix, par le geste, le chat nous regarde et cligne des yeux. Il n’a pas la capacité d’exprimer des paroles selon le modèle humain, mais à sa manière il nous répond, par un clin d’œil. Que se passe-t-il dans ce clin d’œil ? Une communication s’établit, un échange a lieu. Nous regardons l’animal qui nous regarde. Que voyons-nous alors ? Le clin d’œil énigmatique nous pousse à regard...

  19. Remission and rheumatoid arthritis: Data on patients receiving usual care in twenty-four countries

    DEFF Research Database (Denmark)

    Sokka, Tuulikki; Hetland, Merete Lund; Mäkinen, Heidi;

    2008-01-01

    ,848 patients receiving usual care at 67 sites in 24 countries, was used for this study. Patients were clinically assessed by rheumatologists and completed a 4-page self-report questionnaire. The database was analyzed according to the following definitions of remission: American College of Rheumatology (ACR......: The overall remission rate was lowest using the ACR definition of remission (8.6%), followed by the Clin42 (10.6%), Clin28 (12.6%), CDAI (13.8%), MD remission (14.2%), and RAPID3 (14.3%); the rate of remission was highest when remission was defined using the DAS28 (19.6%). The difference between the highest...

  20. Liver stiffness and 30-day mortality in a cohort of patients admitted to hospital

    DEFF Research Database (Denmark)

    Lindvig, Kristoffer; Mössner, Belinda K; Pedersen, Court;

    2012-01-01

    Eur J Clin Invest 2011 ABSTRACT: Background  Transient elastography (TE) is a new noninvasive method to assess the degree of liver fibrosis by measuring liver stiffness. The objective of this study was to determine whether increased liver stiffness in patients admitted to medical wards was associ......Eur J Clin Invest 2011 ABSTRACT: Background  Transient elastography (TE) is a new noninvasive method to assess the degree of liver fibrosis by measuring liver stiffness. The objective of this study was to determine whether increased liver stiffness in patients admitted to medical wards...

  1. Photocarcinogenesis and toxicity of benzoyl peroxide in hairless mice after simulated solar radiation

    DEFF Research Database (Denmark)

    Lerche, Catharina M; Philipsen, Peter A; Poulsen, Thomas;

    2010-01-01

    Topical benzoyl peroxide (BPO) gel has long been used to treat acne vulgaris and has recently been combined with clindamycin (BPO-clin). No skin malignancies have been reported after clinical use of BPO, but there has been concern about the possible carcinogenicity of BPO alone and in combination...... with UV radiation. BPO can promote skin tumorigenesis in a mouse skin chemical carcinogenesis model. As acne vulgaris is frequently localized on sun-exposed areas, we investigated whether BPO or BPO-clin accelerates photocarcinogenesis in combination with simulated solar radiation (SSR) in 12 groups of 25...

  2. Disease: H00323 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available kettsia within the family Rickettsiaceae in the order Rickettsiales. The diseases present with high fever, a...orne rickettsioses around the world: emerging diseases challenging old concepts. Clin Microbiol Rev 18:719-5...PMID:15225980 (description) Parola P Tick-borne rickettsial diseases: emerging risks in Europe. Comp Immunol... Microbiol Infect Dis 27:297-304 (2004) PMID:18755389 (description) Cazorla C, Socolovschi C, Jensenius M, Parola P Tick-borne diseas...es: tick-borne spotted fever rickettsioses in Africa. Infect Dis Clin North Am 22:531-44, ix-x (2008) ...

  3. Sodium Channel Gene Mutations in Children with GEFS+ and Dravet Syndrome: A Cross Sectional Study

    Directory of Open Access Journals (Sweden)

    Seyed Hassan TONEKABONI

    2013-06-01

    before age of one year and psychomotor retardation after age of two years are the most significant criteria in SCN1A mutation positive patients.References Dravet C, Bureau M, Oguni H, Fukuyama Y, Cokar O.Severe myoclonic epilepsy in infancy (Dravet syndrome. In: Roger J, Bureau M, Dravet C, Genton P, Tassinari CA, Wolf P, eds. Epileptic Syndromes in Infancy, Childhood and Adolescence, 4th  ed. London: John Libbey Eurotext Publishers; 2005. p. 89-113.Dalla Bernardina B, Colamaria V, Capovilla G, Bondavalli S. Nosological classification of epilepsies in the first three years years of life. Prog Clin Biol Res 1983;124:165-83.Commission on Classification and Terminology of the International League against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989;30:389-99.Scheffer IE, Zhang. YH, Jansen FE, Dibbens L. Dravet syndrome or genetic (generalized epilepsy with febrile seizures plus? Brain Dev 2009;31(5:394-400.Singh R, Andermann E, Whitehouse WP, Harvey AS, Keene DL, Seni MH, et al. severe myoclonic epilepsy of infancy: extended spectrum of GEFS+? Epilepsia 2001;42(7:837-44.Scheffer IE, Harkin LA, Dibbens LM, Mulley JC, Berkovic SF. Neonatal epilepsy syndromes and generalized epilepsy with febrile seizures plus (GEFS+. Epilepsia 2005;46 Suppl 10:41-7.Harkin LA, McMahon JM, Iona X, Dibbens L, Pelekanos JT, Zuberi SM, et al. The spectrum of SCN1A-related infantile enceptic encephalopathies. Brain 2007;130(Pt 3:843-52.Sun H, Zhang Y, Liang J, Liu X, Ma X, Qin, et al. Seven novel SCN1A mutations in Chinese patients with severe myoclonic epilepsy of infancy. Epilepsia 2008;49:1104-7.Miller SA, Dykes DD, polesky HF. A simple salting out procedure  for  extracting  DNA from  human  cucleated Nucleated cells. Nucleic Acids Res 1988;16(3:2115.Marini C, Scheffer IE, Nabbout R, Mei D, Cox K, Dibbens LM, et al. SCN1A duplications and deletions detected in dravet syndrome: implications for molecular diagnosis. Epilepsia 2009; 50

  4. Comparison of Deflazacort and Prednisone in Duchenne Muscular Dystrophy

    Directory of Open Access Journals (Sweden)

    Parvaneh KARIMZADEH

    2012-03-01

    -Apr;10(2:138-51. Escolar DM, Leshner RT. Muscular dystrophies. In: Swaiman KF, Ashwal S, Ferriero DM. Pediatric Neurology. 4th ed. Philadelphia: Mosby; 2006. p. 1967-86. Sarnat HB, Menkes JH. Disease of the motor unit. In: Menkes JH, Sarnat HB, editors. Child Neurology. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. p. 984-9. Biggar WD, Politano L, Harris VA, Passamano L, Vajsar J, Alman B, et al. Deflazacort in duchenne muscular dystrophy: a comparison of two different protocols. Neuromuscul disord 2004 Sep;14(8-9:476-82. Radley HG, De Luca A, Lynch GS, Grounds MD. Duchenne muscular dystrophy: focus on pharmaceutical and nutritional interventions. Int J Biochem Cell Biol 2007;39(3:469-77.Biggar WD, Klamut HJ, Demacio PC, Stevens DJ. Duchenne muscular dystrophy: current knowledge, treatment and future prospects. Clin Orthop Relat Res 2002 Aug;401:88-106.Sohn RL, Gussoni E. Stem cell therapy for muscular dystrophy. Expert Opin Biol Ther 2004 Jan;4(1:1-9.Houde S, Filiatrault M, Fournier A, Dube J, D’Arcy S, Berube D et al. Deflazacort use in duchenne muscular dystrophy: an 8-year follow-up. Pediatr Neurol 2008 Mar;38(3:200-6.Bonifati MD, Ruzza G, Bonometto P, Berardinelli A, Gorni K, Orcesi K et al. A multicenter double-bind randomized trial of deflazacort versus prednisone in Duchenne muscular dystrophy: analysis after 2 years. Basic Appl Myol 2000;10:171-5.Reitter B. Deflazacort vs. prednisone in Duchenne muscular dystrophy: trends of an ongoing study. Brain Dev 1995;17 Suppl:39-43.Polgar G, Promadhat V. Standard values. In: pulmonary function testing in children: techniques and standards. Philadelphia: W.B. Saunders, 1971:102-3.Biggar WD, Gingras M, Febling DL, Harris VA, Steele CA. Deflazacort treatment of Duchenne muscular dystrophy. J Pediatr 2001 Jan;138(1:45-50. 

  5. Approach To The First Unprovoked Seizure- PART II

    Directory of Open Access Journals (Sweden)

    Mohammad GHOFRANI

    2013-11-01

    , adolescents and young adult. Seizure 1997;6:461-565.39.Berg AT, Shinnar S, Levy SR, Testa FM, et al. Early development of intractable epilepsy in children: A prospective study. Neurology 2001;56:1445-1452.40.Berg At, Shinnar S. The risk of seizure recurrence following a first unprovoked seizure: A quantitative review. Neurology 1991;41:955-972.41.Camfield PR, Camfield CS, Dooley JM, et al. Epilepsy after a first unprovoked seizure in childhood, Neurology 1985;35:1657-1660.42.Commission on epidemiology and prognosis. International League Against Epilepsy. Guidelines for epidemiologic studies on epilepsy. Epilepsia 1993;37:592-596.43.Annegers JF, Shirts SB, Hauser WA, et al. Risk of recurrence after an initial unprovoked seizure. Epilepsia 1986;27:43-50.44.Shinnar S, Berg AT, Moshe SL, Shinnar R. How long do new –onset seizures in children last? Ann Neurol 2001;49:659-664.45.Camfield P, Camfield C, Dooley J, et al. A randomized study of carbamazepine versus no medication after a first unprovoked seizure in childhood. Neurology 1989;39:851-852.46.Chandra B. First Seizure in adult: to treat or not to treat. Clin Neurol Neurosurg 1992;94:861-863.47.Musico M, Beghi E, Solari A, Viani F. Treatment of first Tonic-Clonic Seizure does not improve the prognosis of epilepsy. Neurology 1997;49:991-998.48.American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy (RE9537. Approach To The First Unprovoked Seizure-PART II. Pediatrics 1995;96:538-540.49.Yerby MS. Teratogenic effects of antiepileptic drugs: what do we advise patients? Epilepsia 1997;38-957-958.50.Vinig EP, Melits ED. Dorsen MM, et al. Psychologic and behavioral effects of antiepileptic drugs in children: A double-blind comparison between Phenobarbital and valproic acid. Pediatrics 1987;80: 165-174.51.Berg I, Butler A, Ellis M, Foster J. Psychiatric aspects of epilepsy in childhood treated with carbamazepine, phenytoin, or sodium valporate: a random trial. Dev Med Child Nerol 1993

  6. Student's perception towards learning medical sciences: problem based learning versus lecture based learning methods

    Directory of Open Access Journals (Sweden)

    Padmanabha TS.

    2016-04-01

    Conclusions: Students' percieves that the knowledge and understanding could be very easily acquired by PBL over LBL. Students felt Pharmacology should be taught with both ways, initially LBL followed by PBL for better understanding the concepts for clinical application. [Int J Basic Clin Pharmacol 2016; 5(2.000: 411-415

  7. A retrospective study on drug interaction for pediatric in-patients at Central Public Hospital Haji Adam Malik, Medan for the period of January-June 2012

    Directory of Open Access Journals (Sweden)

    Umi Chairani Manik

    2014-06-01

    Conclusion: The statistical data analysis results showed that there was a significant correlation between the amount of drugs and the number of diagnoses, while age and sex did not show any significant correlation. [Int J Basic Clin Pharmacol 2014; 3(3.000: 512-516

  8. Student's perception and experience of computer assisted learning as a teaching method in experimental pharmacology

    Directory of Open Access Journals (Sweden)

    Deepika Tikoo

    2015-12-01

    Conclusion: The study demonstrates the effectiveness of CAL in teaching experimental pharmacology concepts and the students felt that this method helped them in a better understanding of the topic as the effects were clearly visualized on the screen and that such simulations need to be a part of the standard curriculum. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1168-1174

  9. Disease: H00177 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ers RJ, Waterham HR Peroxisomal disorders I: biochemistry and genetics of peroxisome biogenesis disorders. C...lin Genet 67:107-33 (2005) PMID:12740827 Depreter M, Espeel M, Roels F Human peroxisomal disorders. Microsc Res Tech 61:203-23 (2003) ...

  10. Disease: H00578 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available of cataracts and blue leukocyte inclusion bodies (Doehle-like bodies). Both disorders...iption) Kashtan CE, Segal Y Genetic disorders of glomerular basement membranes. Nephron Clin Pract 118:c9-c1...H, Park YS, Ha IS, Ahn HS, Choi Y, Cheong HI Renal manifestations of patients with MYH9-related disorders. Pediatr Nephrol 26:549-55 (2011) ...

  11. Disease: H00885 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available PMID:15708290 (description) Passeron T, Mantoux F, Ortonne JP Genetic disorders o...f pigmentation. Clin Dermatol 23:56-67 (2005) PMID:22150346 (description) Torchia D Mosaic pigmentation disorders and associated syndromes. J Dermatol 39:414-5 (2012) ...

  12. Disease: H00609 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00609 46,XY disorders of sex development (Other), including: Persistent Mullerian ...duct syndrome; Hypospadias; Cryptorchidism 46,XY disorders of sex development (46,XY DSD) with other various...onca BB, Domenice S, Arnhold IJ, Costa EM 46,XY disorders of sex development (DSD). Clin Endocrinol (Oxf) 70

  13. Disease: H00608 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00608 46,XY disorders of sex development (Disorders in androgen synthesis or actio...n), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS) 46,XY disorders... Domenice S, Arnhold IJ, Costa EM 46,XY disorders of sex development (DSD). Clin ... male sexual differentiation and aetiology of disorders of sex development. Best

  14. Disease: H00582 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available l hematuria is an autosomal dominant disorder characterized by recurrent dysmorphic hematuria detected in childhood. The glomerular... Gubler MC Inherited diseases of the glomerular basement membrane. Nat Clin Pract... Nephrol 4:24-37 (2008) PMID:21071975 (gene, description) Kashtan CE, Segal Y Genetic disorders of glomerular

  15. Cost analysis of antiretroviral agents available in India

    Directory of Open Access Journals (Sweden)

    Sagar S. Panchal

    2015-06-01

    Conclusion: There is wide variation in the prices of antiretroviral agents available in the market. Regulatory authorities, pharma companies, physicians should maximize their efforts to reduce the cost of drugs. [Int J Basic Clin Pharmacol 2015; 4(3.000: 479-482

  16. Cost analysis study of oral antihypertensive agents available in Indian market

    Directory of Open Access Journals (Sweden)

    Ashwini V. Karve

    2014-06-01

    Conclusion: The average percentage price variation of different brands of the same oral antihypertensive drug manufactured in India is very wide. The appraisal and management of marketing drugs should be directed toward maximizing the benefits of therapy and minimizing negative personal and economic consequences. [Int J Basic Clin Pharmacol 2014; 3(3.000: 479-483

  17. Study of variation in prices of oral antiplatelet drugs available in Indian market

    Directory of Open Access Journals (Sweden)

    Abhilasha Rashmi

    2016-06-01

    Conclusions: There is a wide difference in the cost of different brands of oral antiplatelet drugs available in India. The clinicians prescribing these drugs should be aware of these variations in cost to reduce the cost of drug therapy. [Int J Basic Clin Pharmacol 2016; 5(3.000: 810-813

  18. Cost analysis of oral hypolipidemic agents available in India

    Directory of Open Access Journals (Sweden)

    Vihang S. Chawan

    2014-12-01

    Conclusion: There is a wide difference in the cost of different brands of oral hypolipidemic drugs available in India. The clinicians prescribing these drugs should be aware of these variations in cost to reduce the cost of drug therapy. [Int J Basic Clin Pharmacol 2014; 3(6.000: 954-957

  19. Comparison of two different doses of dexmedetomidine infusion on post-operative pain and sedation in patients undergoing laparoscopic surgery

    Directory of Open Access Journals (Sweden)

    Tanmay Tiwari

    2014-12-01

    Conclusion: The perioperative infusion of Dex may be an attractive option during laparoscopic surgery as it, offered better control of intraoperative and post-operative hemodynamics, and decreased post-operative pain level and better sedation scores, as compared with control. [Int J Basic Clin Pharmacol 2014; 3(6.000: 1052-1056

  20. 多西紫杉醇联合5-FU和顺铂改善进展期胃癌生存%Docetaxel and Cisplatin Plus Fluorouracil as First-Line Therapy for Advanced Gastric Cancer Can Improve TTP and OS

    Institute of Scientific and Technical Information of China (English)

    沈琳; 张华

    2008-01-01

    @@ 1 文献来源 van Cutsem E,Moiseyenko VM,Tjulandin S,et al.Phase Ⅲ study of Docetaxel and Cisplatin plus Fluorouracil compared with Cisplatin and Fluorouracil as first-line therapy for advanced gastric cancer:A report of the V325 study group[J].J Clin Oncol,2006,24(31):4991-4997.

  1. Contemplation on new drug approvals by U.S. FDA, 2011-2015

    Directory of Open Access Journals (Sweden)

    Bhaven C. Kataria

    2016-02-01

    Conclusions: For new drugs approved between 2011 and 2015, the U.S. FDA was first to approve majority of new drugs. There was upward trend of new drug approvals in antineoplastic therapeutic area. [Int J Basic Clin Pharmacol 2016; 5(1.000: 55-59

  2. Comparison of new drug approval by regulatory agencies of US, EU and India

    Directory of Open Access Journals (Sweden)

    Bhaven C. Kataria

    2016-02-01

    Conclusions: For new drugs approved between 2011 and 2015, India has lagged behind the US and the EU in approval of new drugs. There was no difference in the patterns of new drug approvals with respect to the therapeutic areas. [Int J Basic Clin Pharmacol 2016; 5(1.000: 112-115

  3. A descriptive study of knowledge of Pharmacovigilance and adverse drug reactions among second professional undergraduate medical students in a teaching hospital

    Directory of Open Access Journals (Sweden)

    Rehana Tabassum

    2015-10-01

    Conclusions: Our study revealed that there are gaps between knowledge regarding ADRs and Pharmacovigilance that needs to be addressed on priority basis for the success of the Pharmacovigilance program and better clinical management of patients in general. [Int J Basic Clin Pharmacol 2015; 4(5.000: 1016-1020

  4. Effect of bevacizumab, which remain after withdrawal of the first dose/s from a single-use vial on diabetic macular edema

    Directory of Open Access Journals (Sweden)

    Mehmet Demir

    2015-02-01

    Conclusion: Bevacizumab which remain in the single use vial after first dose/s is safe and effective for treatment of DME. These results are useful for poor countries. [Int J Basic Clin Pharmacol 2015; 4(1.000: 159-163

  5. Antidiabetic activity of Plumeria rubra L. in normal and alloxan induced diabetic mice

    Directory of Open Access Journals (Sweden)

    Amruta V. Yadav

    2016-06-01

    Conclusions: PR exhibited significant antihyperglycemic activity in normal and alloxan-induced diabetic mice. The results of the present study provide support to the traditional usage of the plant in diabetes. [Int J Basic Clin Pharmacol 2016; 5(3.000: 884-889

  6. Comparative evaluation of amisulpride and escitalopram on Hamilton anxiety rating scale among depression patients in a tertiary care teaching hospital in Nepal

    Directory of Open Access Journals (Sweden)

    Vijay Kaul

    2015-04-01

    Conclusion: Both amisulpride and escitalopram were highly effective in the treatment of anxiety in depression patients during the study period. Further, more clinical studies with longer follow-up duration are needed to substantiate the therapeutic effects of amisulpride. [Int J Basic Clin Pharmacol 2015; 4(2.000: 349-353

  7. Digital protocol for reference-based guided surgery and immediate loading: a prospective clinical study

    NARCIS (Netherlands)

    A. Tahmaseb; R. de Clerck; I. Aartman; D. Wismeijer

    2012-01-01

    PURPOSE: To evaluate the performance of a computer-aided three-dimensional planning protocol in combination with previously inserted reference mini-implants and CAD/CAM technology to restore completely edentulous patients. The study evaluated implant and superstructure survival in a prospective clin

  8. Nomograms to Predict Pathologic Complete Response and Metastasis-Free Survival after Preoperative Chemotherapy for Breast Cancer%采用列线图对乳腺癌进行新辅助治疗后病理完全缓解及无复发生存的预测

    Institute of Scientific and Technical Information of China (English)

    王永胜; 廖宁

    2007-01-01

    @@ 1文献类型 治疗. 2证据水平 2b. 3文献来源 Rouzier R, Pusztai L, Delaloge S, et al.Nomograms to predict pathologic complete response and metastasis-free survival after preoperative chemotherapy for breast cancer [J]. J Clin Oncol,2005,23(33): 8331-8339.

  9. The effect of teacher interpersonal behaviour on students' subject-specific motivation

    NARCIS (Netherlands)

    den Brok, P.; Levy, J.; Brekelmans, M.; Wubbels, Th.

    2006-01-01

    This study brings together insights from research on teaching and learning in specific subjects, learning environments research and effectiveness research by linking teacher interpersonal behaviour to students’ subject-related attitudes. Teaching was studied in terms of a model originating from clin

  10. Disease: H00559 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available description, gene) Maher ER, Neumann HP, Richard S von Hippel-Lindau disease: a clinical and scientific revi...amasaki I, Tamura K, Okuda H, Furihata M, Ashida S Von Hippel-Lindau disease: molecular pathological basis, clinical... criteria, genetic testing, clinical features of tumors and treatment. Jpn J Clin Oncol 36:337-43 (2

  11. Disease: H00321 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available :7267960 (description) Schmidt U, Chmel H, Kaminski Z, Sen P The clinical spectrum of Campylobacter fetus in...980) PMID:9310640 Jousimies-Somer H Recently described clinically important anaerobic bacteria: taxonomic aspects and update. Clin Infect Dis 25 Suppl 2:S78-87 (1997) ...

  12. Disease: H00287 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00287 Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome Pyogenic sterile arthritis... with early onset, developing erosive arthritis. It is inherited in an autosomal dominant fashion. Patients ...al dominant disorder of pyogenic sterile arthritis, pyoderma gangrenosum, and acne: PAPA syndrome. Mayo Clin

  13. Comparison of efficacy of levofloxacin-metronidazole combination versus ceftriaxone in cases of moderate diabetic foot infection

    Directory of Open Access Journals (Sweden)

    Swati V. Patil

    2016-10-01

    Conclusions: Even though combination of levofloxacin-metronidazole and ceftriaxone alone had similar outcomes in terms of efficacy, on contrary in comparison of cost and convenience, levofloxacin - metronidazole therapy was proved better than ceftriaxone in treatment of diabetic foot ulcers. [Int J Basic Clin Pharmacol 2016; 5(5.000: 1775-1779

  14. Genetics Home Reference: type 1 diabetes

    Science.gov (United States)

    ... JM, Mayer-Davis EJ. Epidemiology of type 1 diabetes. Endocrinol Metab Clin North Am. 2010 Sep;39(3):481-97. doi: 10.1016/j.ecl.2010.05.011. Review. Citation on PubMed or Free article on PubMed ... G. Insights into type 1 diabetes provided by genetic analyses. Curr Opin Endocrinol Diabetes ...

  15. Symptom experience associated with immunosuppressive drugs after liver transplantation in adults : possible relationship with medication non-compliance?

    NARCIS (Netherlands)

    Drent, Gerda; Moons, P.; De Geest, S.; Kleibeuker, J. H.; Haagsma, E. B.

    2008-01-01

    Symptom experience (occurrence and perceived distress) associated with side effects of immunosuppressive medications in organ transplant patients may well be associated with poorer quality of life and medication non-compliance. The aims of this study were: first, to assess symptom experience in clin

  16. ALLERGY AND IMMUNOLOGY

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    3.1 Autoimmune disease2003266 Using GST-tag to capture protein interaction of an interferon-inducible systemic lupus associated gene, IFIT1. YE Shuang(叶霜), et al. Dept Rheumatol, Renji Hosp, Clin Center Rheum Dis, Shanghai 2nd Med

  17. A study of potential drug-drug interactions among critically ill patients at a tertiary care hospital

    Directory of Open Access Journals (Sweden)

    Manjeeta Gupta

    2016-08-01

    Conclusions: The present study showed high concomitant administration of potentially interacting drugs. The prevalence confirmed the association of age and polypharmacy. Vigilant prescribing approach is needed to prevent hazardous outcomes of pDDI. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1281-1285

  18. Evaluation of wound healing activity of ethanolic extract of Azadirachta indica leaves on incision and excision wound models in Wister albino rats

    Directory of Open Access Journals (Sweden)

    H. N. Nagesh

    2015-12-01

    Conclusion: The study revealed promising wound healing activity of ethanolic extract of A. indica and provides a scientific rationale for the traditional use in the management of wounds. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1178-1182

  19. To study the efficacy and tolerability of fenugreek seed powder as add-on therapy with metformin in patients of type-2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Manmeet Kaur

    2016-04-01

    Conclusions: This study shows the beneficial effects of fenugreek seeds on glycemic profile in patients of Type 2 DM and can be used as an add-on therapy with metformin in management of Type 2 DM. [Int J Basic Clin Pharmacol 2016; 5(2.000: 378-383

  20. An epidemiological survey to assess the clinical use of cephalosporins in community-acquired respiratory tract infections

    Directory of Open Access Journals (Sweden)

    Vikram Sobti

    2015-06-01

    Conclusion: In-clinic use of cefpodoxime as monotherapy is preferred in upper respiratory tract infections. However, clinicians recommend a combination therapy of cefpodoxime and levofloxacin in lower respiratory tract infections. [Int J Basic Clin Pharmacol 2015; 4(3.000: 547-550

  1. Genetics Home Reference: hidradenitis suppurativa

    Science.gov (United States)

    ... Apr;60(4):539-61; quiz 562-3. doi: 10.1016/j.jaad.2008.11.911. Review. ... Acad Dermatol. 2009 Jul;61(1):51-7. doi: 10.1016/j.jaad.2009.02.013. Epub ... Dermatol Clin. 2010 Oct;28(4):779-93. doi: 10.1016/j.det.2010.07.003. Review. ...

  2. Immunity

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    970239 The effect of interleukin 6 against cytopeniaand suppressed phagocytosis of macrophage caused bychemotherapy. ZHANG Lichao(张利朝), et al.Tangdu Hosp, 4th Milit Med Univ, Xian, 710038. ChinJ Clin Oncol 1997; 24(4): 252-255. Objective: To explore The effect of interleukin 6against cytopenia and suppressed phagocytosis ofmacrophage caused by chemotherapy. Methods:Inter-

  3. Efficacy of terbutaline in preterm labour - our experience

    Directory of Open Access Journals (Sweden)

    Priyadarshini Bai G.

    2016-10-01

    Conclusions: Administration of terbutaline prolonged labour without any serious maternal complications and better neonatal outcome as 90% of the neonates were born without any complications. Hence, terbutaline can be used as a safe and effective tocolytic agent among patients presenting with preterm labour. [Int J Basic Clin Pharmacol 2016; 5(5.000: 2118-2122

  4. Prospective single blind placebo-controlled randomized clinical trial to assess the efficacy and safety of metformin in promoting wound healing and weight reduction in non-diabetic overweight post-operative female patients

    Directory of Open Access Journals (Sweden)

    C. Meenal

    2015-04-01

    Conclusions: Our study has shown metformin having best wound healing and weight reducing effect without producing hypoglycemia. Long-term studies on all types of surgeries in both males and females including emergencies are suggested. [Int J Basic Clin Pharmacol 2015; 4(2.000: 363-370

  5. Growth Hormone Receptor Antagonist Treatment Reduces Exercise Performance in Young Males

    DEFF Research Database (Denmark)

    Goto, K.; Doessing, S.; Nielsen, R.H.;

    2009-01-01

    between the groups in terms of changes in serum free fatty acids, glycerol, (V) over dotO(2), or relative fat oxidation. Conclusion: GH might be an important determinant of exercise capacity during prolonged exercise, but GHR antagonist did not alter fat metabolism during exercise. (J Clin Endocrinol...... Metab 94: 3265-3272, 2009) Udgivelsesdato: 2009/9...

  6. An antiinflammatory actions of exenatide

    Directory of Open Access Journals (Sweden)

    S Yu Vorotnikova

    2012-12-01

    Full Text Available Реферат по статье: Chaudhuri A, Ghanim H, Vora M, Sia CL, Korzeniewski K, Dhindsa S, Makdissi A, Dandona P. Exenatide exerts a potent antiinflammatory effect. J Clin Endocrinol Metab. 2012 Jan; 97(1: 198-207.

  7. Immune thrombocytopenic purpura following Varicella zoster infection

    Directory of Open Access Journals (Sweden)

    Alper Dai

    2011-03-01

    Full Text Available Although thrombocytopenia is a rarely observed complicationfollowing chickenpox, it can lead to serious bleedingproblems. In order to underline rare hematologiccomplications of varicella infection and the importanceof vaccination, here we reported a seven year old boywho developed severe thrombocytopenia duringvaricella infection and gave good response to intravenousimmunoglobulin therapy. J Clin Exp Invest 2011;2(1: 85-87

  8. Diabetes mellitus

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    2008395 Evaluating the feature of hypoglycemia detected by continuous glucose monitoring system during temporary continuous subcutaneous insulin infusion in type 2 diabetes patients. LI Ming(李鸣), et al.Shanghai Diabet Clin Center, Dept Endocrinol & Metab, Shanghai Jiaotong Univ, Shanghai 200233. Natl Med J China 2008;88(24):1679-1682.

  9. Pharmacoeconomical evaluation of hypertension with diabetes mellitus in a teaching hospital in urban Bangalore

    Directory of Open Access Journals (Sweden)

    Rajat Rana

    2016-04-01

    Conclusions: This study concludes that the there is a huge economic burden on the patient from the lower income group. Medication cost and diagnostic cost are among the major factors that accounts for the total health care cost. [Int J Basic Clin Pharmacol 2016; 5(2.000: 473-477

  10. Evaluation of analgesic activity of Emblica officinalis in albino rats

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    Bhomik Goel

    2014-04-01

    Results: Emblica officinalis extract did not produced statistically significant (p>0.05 analgesia when compared with the control group in hot plate latency, but produced a statistically significant reduction in 6% NaCl induced abdominal writhing (pEmblica officinalis exhibit analgesic activity involving peripheral mechanisms. [Int J Basic Clin Pharmacol 2014; 3(2.000: 365-368

  11. Genetics Home Reference: glucose-galactose malabsorption

    Science.gov (United States)

    ... Turk E. Intestinal absorption in health and disease--sugars. Best Pract Res Clin Gastroenterol. 2003 Dec;17(6):943-56. Review. ... resources on this site should not be used as a substitute for professional medical care or advice. Users with ...

  12. Anticonvulsant profile of nardostachys jatamansi roots in albino rats

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    Purushotham K.

    2016-06-01

    Conclusions: The anticonvulsant activity of ethanolic extract of nardostachys jatamansi roots was less when compared to Sodium Valproate in Maximal Electro Shock model. Whereas, in Pentylenetetrazole induced seizure model, anticonvulsant activity of ethanolic extract of nardostachys jatamansi roots was comparable to sodium valproate. [Int J Basic Clin Pharmacol 2016; 5(3.000: 758-762

  13. Toxicological evaluation and oral glucose tolerance test of ethanolic leaf extract of Barleria cristata L. in wistar albino rats

    Directory of Open Access Journals (Sweden)

    R. Narmadha

    2013-12-01

    Conclusion: EtBc was revealed the non-toxic nature used for acute toxicity studies and among various doses of this extract, 400 mg/kg brought an effective hypoglycemic activity in wistar albino rats. [Int J Basic Clin Pharmacol 2013; 2(6.000: 742-746

  14. A snake bite case developing thrombocytopenia

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    Asım Adıgön

    2012-06-01

    Full Text Available We present a case of a twenty four year old man whowas bitten by a snake on his right leg. It was a severeenvenomation with ensuing marked edema and severepain with complicated coagulation defects. After medicaltreatmant with antivenom the patient discharged withoutany complication. J Clin Exp Invest 2012; 3(2: 293-295

  15. Cost analysis of different brands of antianginal drugs available in India

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    L. Akila

    2015-10-01

    Conclusions: To increase the benefit to the patient and reduce drug in compliance, doctors should be trained to be familiar from internship period itself about the brand names of cost-effective drugs with good safety profile for a long period. [Int J Basic Clin Pharmacol 2015; 4(5.000: 860-863

  16. Genetics Home Reference: Huntington disease-like syndrome

    Science.gov (United States)

    ... what to consider in patients with a negative Huntington's disease gene test. Nat Clin Pract Neurol. 2007 Sep;3( ... San C, Bellance R, Brice A, Durr A. Huntington's disease-like phenotype due to trinucleotide repeat expansions in the TBP and JPH3 genes. Brain. 2003 Jul;126(Pt 7):1599-603. ...

  17. Evaluation of anticonvulsant activity of volatile oil extract of Nigella sativa seeds by chemically induced seizure model in albino rats

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    Asmatanzeem Bepari

    2016-08-01

    Conclusions: The N. sativa seeds showed anticonvulsant activity in pentylenetetrazole induced seizure model of epilepsy. This study showed that volatile oil of N. sativa seeds potentiated the effect of sodium valproate. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1300-1307

  18. Evaluation of anti-depressant effect of lemon grass (Cymbopogon citratus in albino mice

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    Sujata Dudhgaonkar

    2014-08-01

    Results: Lemon grass at the above doses significantly reduced the immobility time in both the tests compared with the control (C. citratus has significant anti-depressant activity comparable to imipramine. [Int J Basic Clin Pharmacol 2014; 3(4.000: 656-660

  19. Clonidine as an adjuvant to local anesthetic in supraclavicular brachial plexus block: a randomized, double blinded placebo controlled study

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    Preeti Rustagi

    2016-10-01

    Conclusions: Clonidine 2 and micro;g / kg added to 10 ml of 0.5 % Bupivacaine + 20 ml of 2% lignocaine with adrenaline (1:200000 is a good option for improving the quality and duration of supraclavicular brachial plexus block. [Int J Basic Clin Pharmacol 2016; 5(5.000: 1892-1897

  20. Drug utilization study of psychotropic drugs in outdoor patients in a tertiary care hospital attached with a medical college

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    Chintan Madhusudan Doshi

    2015-12-01

    Conclusion: Overall, the drugs were prescribed rationally. Benzodiazepine should be prescribed only for short-term duration. Use of central acting anticholinergic drugs with all antipsychotic drugs was not justified. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1220-1223

  1. Drug utilization pattern in acute coronary syndrome at tertiary care hospital: a prospective cross-sectional observational study

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    Praveen Choudhary

    2016-04-01

    Conclusions: The present study provides valuable insight about the overall pattern of drug used in Acute Coronary syndrome. Physician should be encouraged to prescribe drugs with generic name. [Int J Basic Clin Pharmacol 2016; 5(2.000: 513-516

  2. Preventing Clinical Leakage of Colonic Anastomoses with A Fibrin-Coated Collagen Patch Sealing - An Experimental Study

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    Tyge Nordentoft

    2014-08-01

    Conclusion: A collagen patch coated with fibrin glue components efficiently seals leaking gastrointestinal anastomoses in pigs. Whether these results may be applied to humans in order to prevent clinical anastomotic dehiscence must be investigated in future randomized clinical studies. [Arch Clin Exp Surg 2014; 3(4.000: 201-206

  3. Low-Dose lnterleukin-2 Immunotherapy Does Not Improve Outcome of Patients Age 60 Years and Older with Acute Myeloid Leukemia in First Complete Remission%首次缓解后使用小剂量IL-2免疫治疗不能改善≥60岁老年急性髓性白血病患者预后

    Institute of Scientific and Technical Information of China (English)

    马军; 吴穗晶; 杜欣

    2009-01-01

    @@ 1文献来源 Low-dose Interleukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leukemia in first complete remission: Cancer and Leukemia Group B Study 9720. [J]. J Clin Oncol, 2008,12(26):4934-4939.

  4. 急性髓性白血病的年龄相关危险因素特征及化疗剂量敏感性研究的评价%Assessment of the Age-Related Risk Profile and Chemotherapy Dose Response in Acute Myeloid Leukemia

    Institute of Scientific and Technical Information of China (English)

    杜欣; 郭荣

    2009-01-01

    @@ 1 文献来源 Buchner T, Berdel WE, Haferlach C, et al, Age-related risk profile and chemotherapy dose response in acute myeloid leukemia: A study by the German Acute Myeloid Leukemia Cooperative Group [J]. J Clin Oncol, 2009,27(1):61-69.

  5. Evaluation of nootropic activity of Curcuma longa leaves in diazepam and scopolamine-induced amnesic mice and rats

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    Nayana Reddy

    2015-08-01

    Conclusion: This could be by inhibiting the levels of cholinesterase concentration of enzyme and thereby increasing the concentration of acetylcholine level in brain and improving cognition-memory performance. [Int J Basic Clin Pharmacol 2015; 4(4.000: 714-719

  6. Drug utilization pattern of antimicrobial drugs in intensive care unit of a tertiary care hospital attached with a medical college

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    Rutvij Hedamba

    2016-02-01

    Conclusions: Despite of limitations of present study it gives important conclusion about how antimicrobial drugs are used in GGGH ICU. This information can be used for improvement of current treatment strategies. [Int J Basic Clin Pharmacol 2016; 5(1.000: 169-172

  7. Assessment of medication adherence among hypertensive patients: a cross-sectional study

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    Anup Bhusal

    2016-08-01

    Conclusions: Overall the medication adherence was poor in hypertensive patients. Adherence to therapeutic regimens is an important factor in blood pressure control among hypertensive patients and needs priority. Health education related to medication adherence needs be improved in hypertensive patients. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1606-1612

  8. A study on prescribing pattern of antihypertensives in adult patients attending in a tertiary care hospital of Assam, India

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    Pavel Sikidar

    2016-06-01

    Conclusions: Our study shows that the most commonly prescribed drug classes involved were angiotensin II receptor antagonists followed by calcium channel blocker and the anti-hypertensive drug combinations among hypertensive patients were considerable and this practice positively impacted on the overall blood pressure control. [Int J Basic Clin Pharmacol 2016; 5(3.000: 975-978

  9. Disease: H00300 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available alosporins. ICD-10: A04.8 PMID:9105752 (description, env_factor) Sanders WE Jr, Sanders CC Enterobacter spp.: pathogens poised to flo...urish at the turn of the century. Clin Microbiol Rev 10:220-41 (1997) PMID:16813978

  10. Safety evaluation of directly observed treatment short course (DOTS regimen in a tertiary care hospital, Pune

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    Nishant P. Dalal

    2014-04-01

    Conclusion: ADRs induced by DOTS are common and there is need of incorporating pharmacovigilance system for this vital public health program. Counseling of patients for timely prevention, detection, and management of ADRs will help in minimizing the further occurrence of ADRs. [Int J Basic Clin Pharmacol 2014; 3(2.000: 369-376

  11. A randomised control study on neurosensory outcomes of ilioingunal neurectomy in Lichtenstein's hernia repair

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    Annappa Kudva

    2016-06-01

    Conclusion: The severity of pain in the neurectomy group was less than the control group. There were no significant dif- ferences in the neurosensory outcomes of prophylactic ilioinguinal neurectomies in open mesh hernia repair compared to nerve preservation and hence prophylactic neurectomy is presently the choice of most surgeons. [Arch Clin Exp Surg 2016; 5(2.000: 94-99

  12. A descriptive study of prevalence, pattern and attitude of self-medication among second professional medical students in a tertiary care center

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    Vineeta Sawhney

    2015-06-01

    Conclusion: Our study showed that self-medication is widely practiced among students, easy availability of medicine probably being the cause. Educating the students regarding advantages and disadvantages of self-medication is necessary to create awareness. [Int J Basic Clin Pharmacol 2015; 4(3.000: 542-546

  13. Erratum

    OpenAIRE

    Samtani, Mahesh; Sheehan,; Fu; Remmerie,; Sliwa,, K.; Alphs, Larry

    2012-01-01

    Samtani MN, Sheehan JJ, Fu D-J, Remmerie B, Sliwa JK, Alphs L. Management of antipsychotic treatment discontinuation and interruptions using model-based simulations. Clin Pharmacol. 2012;4:25–40. The video abstract was not included on page 25 for this paper.Read the original article  

  14. 77 FR 18833 - Government-Owned Inventions; Availability for Licensing

    Science.gov (United States)

    2012-03-28

    ..., Sacks G, Chandramohan D, Chow CC, Wang YC, Gortmaker SL, Swinburn BA. Quantification of the effect of... changes in free-living energy intake and its confidence interval. Am J Clin Nutr. 2011 Jul;94(1):66- 74. 3. Hall KD. Predicting metabolic adaptation, body weight change, and energy intake in humans. Am J...

  15. PSYCHIATRIC DISORDER

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    14.1 Schizophrenia2004161 Association of the polymorphism of promoter region of the 5HT2C receptor gene with early therapeutic response to antipsychotic agent in first-episode schizophrenic patients. YAO Zhijian (姚志剑) , et al. Dept & Clin Sci Center, Nanjing Brain Hosp & Nanjing Med Univ, Nanjing. 210029. Chin J Nerv Ment Dis 2003; 29 (6):.438-441.

  16. A prospective study to analyse antibiotic susceptibility pattern of Pseudomonas aeruginosa in a tertiary care hospital

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    Syed S. Ameen

    2016-08-01

    Conclusions: Carbapenems and piperacillin-tazobactam were the best antipseudomonal agents with highest sensitivity to P. aeruginosa. FQs, gentamicin and tobramycin were the least effective drugs against P. aeruginosa as monotherapy. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1311-1314

  17. Determination of minimum inhibitory concentration of third generation cephalosporins and fluoroquinolones on clinical isolates of Pseudomonas aeruginosa

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    Bapurao Motiram Bite

    2015-12-01

    Conclusion: MIC values for resistant strains of P. aeruginosa ranged from 0.03 to 32 and micro;g/ml for fluoroquinolones and 0.5-512 and micro;g/ml for third generation cephalosporins. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1142-1146

  18. Screening of various leaf extracts of Chromolaena odorata L. for biochemical constituents and antimicrobial sensitivity

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    Nagesh Kamath

    2015-02-01

    Conclusions: The ethanolic extract of C. odorata exhibited significant antimicrobial activity. The plant extracts could be used to treat resistant form of prevailing infections. Successful antimicrobial drugs can be developed out of these extracts if specific compounds are isolated and purified. [Int J Basic Clin Pharmacol 2015; 4(1.000: 89-97

  19. Evaluation of burn wound healing property of ocimum sanctum by monitoring of period of re-epithelization in rabbits

    Directory of Open Access Journals (Sweden)

    Vaibhav K. Gupta

    2016-02-01

    Conclusions: Group treated with ointment silver sulfadiazine + O. sanctum showed minimum re-epithelization period. So, the most effective treatment for burn wound healing in this study was ointment silver sulfadiazine + O. sanctum. [Int J Basic Clin Pharmacol 2016; 5(1.000: 146-148

  20. Prophylactic Cranial Irradiation in Local Advanced Non Small-Cell Lung Cancer: Result from A Multi Center Clinical Trial from German%局部晚期非小细胞肺癌患者的预防性脑照射——来自德国的多中心临床试验结果

    Institute of Scientific and Technical Information of China (English)

    樊旼; 徐崇锐

    2008-01-01

    @@ 1 文献来源 ①Stuschke BM,Eberhardt W,P(o)ttgen C,et al.Prophylactic cranial irradiation in locally advanced non-small-cell lung cancer after muhimodality treatment:Long-term follow-up and investigations of late neuropsychologic effects[J].J Clin Oncol,1999,17:2700-2709.