WorldWideScience

Sample records for clin dev prgms

  1. Haiti DevResults

    Data.gov (United States)

    US Agency for International Development — DevResults is a web-based portfolio management system that tracks program data for the Haiti Mission that was awarded in April of 2013. (The Mozambique and/or...

  2. Using Activity Metrics for DEVS Simulation Profiling

    Directory of Open Access Journals (Sweden)

    Muzy A.

    2014-01-01

    Full Text Available Activity metrics can be used to profile DEVS models before and during the simulation. It is critical to get good activity metrics of models before and during their simulation. Having a means to compute a-priori activity of components (analytic activity may be worth when simulating a model (or parts of it for the first time. After, during the simulation, analytic activity can be corrected using dynamic one. In this paper, we introduce McCabe cyclomatic complexity metric (MCA to compute analytic activity. Both static and simulation activity metrics have been implemented through a plug-in of the DEVSimPy (DEVS Simulator in Python language environment and applied to DEVS models.

  3. Software Development with DevOps

    OpenAIRE

    Kristinsson, Rögnvaldur

    2015-01-01

    The goal of the study was to introduce DevOps in software development, its methods and approaches to software development. I was introduced to the subject by one of my teach-ers, which let me into further studies and researched on the subject and finally choosing it for the study. The subject was completely new to me when I started the study which I found inspirational as I was learning a new and an interesting subject on a daily basis dur-ing the process of writing the study. The materia...

  4. Dev konka bülloza piyoseli

    Directory of Open Access Journals (Sweden)

    Cüneyt Kucur

    2014-06-01

    Full Text Available Konka bülloza,havalanmış (pnömatize veya içinde bir havalı hücre bulunan orta konka için kullanılan bir terimdir. Genellikle asemptomatik olmakla birlikte pnömatizasyonun büyüklüğüne ve nazal septumla olan ilişkisine göre burun tıkanıklığı semptomları verebilir ve ostiomeatal komplekse bası oluşturmakta ise tikanmasina neden olarak sinüzite yol açabilir. Piyosele dönüşmesi nadirdir. Dev konka bülloza endoskopİk muayenede orta konkanin genişlemiş bir bölümü olarak görülür. Konka bülloza kesin tanısı paranazal sinus bilgisayarlı tomografisi (BT ile koyulur. Tedavisinde endoskopik olarak orta konkanın lateral parsiyel rezeksiyonu yeterli ve minimal invazif bir yöntemdir. Bu yazıda sağ nazal pasajı tamamen tıkayan ve nazal vestibüle kadar uzanım gösteren ve aynı tarafta sinüzite yol açan tek taraflı dev konka bülloza piyoseli olgusu sunulmuştur.

  5. The GenDev Curriculum Development Workshop.

    Science.gov (United States)

    D'cunha, J

    1997-01-01

    This article describes the second Curriculum Development Workshop held in May 1997 at the Asian Institute of Technology (AIT) in Bangkok, Thailand. The workshop aimed to review critically and restructure the Gender and Development Studies (GenDev) curriculum and to assess AIT's role in training gender experts for the region. Participants included 22 people from 16 countries in Asia, Europe, and the US who were teaching graduate students about gender issues and who were activists with nongovernmental organizations working on gender issues. It was determined that the following were required courses: Culture, Knowledge and Gender Relations; Gender, Technology, and Development; Principles of Gender Research and Methodology in Science and Technology; and Gender Analysis and Field Methods. Other suggested core courses included: Gender and Natural Resource Management; Enterprise Management, Technology, and Gender; Gender and Agrarian Reform; Urbanization: A Gender Perspective; Gender-Responsive Development Planning; and Gender and Economic Change: Past and Present Concerns. Participants distinguished between GenDev courses offered to anyone attending AIT and training courses designed to produce gender experts in the region. The aim of training courses for AIT graduate students was to sensitize potential managers, technologists, and others on gender issues and to create awareness of the importance of including gender perspectives within decision-making, policy formation, and implementation. Training courses to produce gender experts should be directed to those with a prior background in gender studies and include gender analysis in field methods. Participants agreed that there should be an independent and autonomous field of gender and development studies. Participants made six recommendations for such a field of study. PMID:12179927

  6. Embracing Agile methodology during DevOps Developer Internship Program

    OpenAIRE

    Patwardhan, Amol; Kidd, Jon; Urena, Tiffany; Rajgopalan, Aishwarya

    2016-01-01

    The DevOps team adopted agile methodologies during the summer internship program as an initiative to move away from waterfall. The DevOps team implemented the Scrum software development strategy to create an internal data dictionary web application. This article reports on the transition process and lessons learned from the pilot program.

  7. Group-enabled DEVS model construction methodology for distributed organizations

    Science.gov (United States)

    Sarjoughian, Hessam S.; Vahie, Sankait; Lee, James D.

    1997-06-01

    A USAF project has been initiated to enable groupware that currently supports IDEF activity model capture to be extended to support DEVS model construction. The methodology developed for this purpose enables team participants to enter activity data and then be queried for additional data that support DEVS system decomposition, assigning the activities to components and adding in relevant dynamics.

  8. Crystallization and preliminary crystallographic analysis of the second GAF domain of DevS from Mycobacterium smegmatis

    International Nuclear Information System (INIS)

    The second GAF domain of the hypoxia-sensing DevS from M. smegmatis has been crystallized. The crystal belonged to space group P61 and diffracted to 2.0 Å resolution. Mycobacterium tuberculosis is known to transform into the nonreplicating persistence state under the influence of hypoxia or nitric oxide. DevS-DevR is a two-component regulatory system that mediates the genetic response for the transformation. DevS is a histidine kinase that contains two GAF domains for sensing hypoxia or nitric oxide. The second GAF from M. smegmatis DevS was crystallized using the sitting-drop vapour-diffusion method in the presence of sodium citrate and 2-propanol as precipitants. X-ray diffraction data were collected from crystals containing selenomethionine to a maximum resolution of 2.0 Å on a synchrotron beamline. The crystals belong to the hexagonal space group P61. The asymmetric unit contains one molecule, corresponding to a packing density of 2.5 Å3 Da−1. The selenium substructure was determined by the single anomalous dispersion method and structure refinement is in progress

  9. DevS/DosS sensor is bifunctional and its phosphatase activity precludes aerobic DevR/DosR regulon expression in Mycobacterium tuberculosis.

    Science.gov (United States)

    Kaur, Kohinoor; Kumari, Priyanka; Sharma, Saurabh; Sehgal, Snigdha; Tyagi, Jaya Sivaswami

    2016-08-01

    Two-component systems, comprising histidine kinases and response regulators, empower bacteria to sense and adapt to diverse environmental stresses. Some histidine kinases are bifunctional; their phosphorylation (kinase) and dephosphorylation (phosphatase) activities toward their cognate response regulators permit the rapid reversal of genetic responses to an environmental stimulus. DevR-DevS/DosR-DosS is one of the best-characterized two-component systems of Mycobacterium tuberculosis. The kinase function of DevS is activated by gaseous stress signals, including hypoxia, resulting in the induction of ~ 48-genes DevR dormancy regulon. Regulon expression is tightly controlled and lack of expression in aerobic Mtb cultures is ascribed to the absence of phosphorylated DevR. Here we show that DevS is a bifunctional sensor and possesses a robust phosphatase activity toward DevR. We used site-specific mutagenesis to generate substitutions in conserved residues in the dimerization and histidine phosphotransfer domain of DevS and determined their role in kinase/phosphatase functions. In vitro and in vivo experiments, including a novel in vivo phosphatase assay, collectively establish that these conserved residues are critical for regulating kinase/phosphatase functions. Our findings establish DevS phosphatase function as an effective control mechanism to block aerobic expression of the DevR dormancy regulon. Asp-396 is essential for both kinase and phosphatase functions, whereas Gln-400 is critical for phosphatase function. The positive and negative functions perform opposing roles in DevS: the kinase function triggers regulon induction under hypoxia, whereas its phosphatase function prevents expression under aerobic conditions. A finely tuned balance in these opposing activities calibrates the dormancy regulon response output. PMID:27327040

  10. Characterization of Codon usage bias in the newly identified DEV UL18 gene

    Science.gov (United States)

    Chen, Xiwen; Cheng, Anchun; Wang, Mingshu; Xiang, Jun

    2011-10-01

    In this study, Codon usage bias (CUB) of DEV UL18 gene was analyzed, the results showed that codon usage bias in the DEV UL18 gene was strong bias towards the synonymous codons with A and T at the third codon position. Phylogenetic tree based on the amino acid sequences of the DEV UL18 gene and the 27 other herpesviruses revealed that UL18 gene of the DEV CHv strain and some fowl herpesviruses such as MeHV-1, GaHV-2 and GaHV-3 were clustered within a monophyletic clade and grouped within alphaherpesvirinae. The ENC-GC3S plot indicated that codon usage bias has strong species-specificity between DEV and 27 reference herpesviruses, and suggests that factors other than gene composition, such as translational selection leading to the codon usage variation among genes in different organisms, contribute to the codon usage among the different herpesviruses. Comparison of codon preferences of DEV UL18 gene with those of E. coli , yeast and humans showed that there were 20 codons showing distinct usage differences between DEV UL18 and yeast, 22 between DEV UL18 and humans, 23 between DEV UL18 and E.coli, which indicated the codon usage bias pattern in the DEV UL18 gene was similar to that of yeast. It is infered that the yeast expression system may be more suitable for the DEV UL18 expression.

  11. Periton Biyopsisinin Nadir Bir Komplikasyonu: ?ntraabdominal Dev Apse

    OpenAIRE

    NAD?R, I??lay; ÖZ?N, Yasemin; KILIÇ, Mesut Zeki Yalın; Turhan, Nesrin; ?A?MAZ, Nurgül

    2009-01-01

    Asit nedeni ile etyolojik ara?tırma yapılan hastada ultra-sonografi e?li?inde periton biyopsisi yapıld?. Ancak biyop-siye sekonder iyatrojenik intraabdominal dev apse geli?ti. Hasta acil laparotomiye alınd?. Peroperatif alınan periton biyopsisi tüberküloz olarak rapor edildi. Bu çalışmada periton biyopsisinin nadir bir komplikasyonu literatür bilgileri e?li?inde sunuldu.

  12. ClinVar: public archive of interpretations of clinically relevant variants.

    Science.gov (United States)

    Landrum, Melissa J; Lee, Jennifer M; Benson, Mark; Brown, Garth; Chao, Chen; Chitipiralla, Shanmuga; Gu, Baoshan; Hart, Jennifer; Hoffman, Douglas; Hoover, Jeffrey; Jang, Wonhee; Katz, Kenneth; Ovetsky, Michael; Riley, George; Sethi, Amanjeev; Tully, Ray; Villamarin-Salomon, Ricardo; Rubinstein, Wendy; Maglott, Donna R

    2016-01-01

    ClinVar (https://www.ncbi.nlm.nih.gov/clinvar/) at the National Center for Biotechnology Information (NCBI) is a freely available archive for interpretations of clinical significance of variants for reported conditions. The database includes germline and somatic variants of any size, type or genomic location. Interpretations are submitted by clinical testing laboratories, research laboratories, locus-specific databases, OMIM®, GeneReviews™, UniProt, expert panels and practice guidelines. In NCBI's Variation submission portal, submitters upload batch submissions or use the Submission Wizard for single submissions. Each submitted interpretation is assigned an accession number prefixed with SCV. ClinVar staff review validation reports with data types such as HGVS (Human Genome Variation Society) expressions; however, clinical significance is reported directly from submitters. Interpretations are aggregated by variant-condition combination and assigned an accession number prefixed with RCV. Clinical significance is calculated for the aggregate record, indicating consensus or conflict in the submitted interpretations. ClinVar uses data standards, such as HGVS nomenclature for variants and MedGen identifiers for conditions. The data are available on the web as variant-specific views; the entire data set can be downloaded via ftp. Programmatic access for ClinVar records is available through NCBI's E-utilities. Future development includes providing a variant-centric XML archive and a web page for details of SCV submissions. PMID:26582918

  13. Your data is your dogfood: DevOps in the astronomical observatory

    CERN Document Server

    Economou, Frossie; Norris, Pat

    2014-01-01

    DevOps is the contemporary term for a software development culture that purposefully blurs distinction between software development and IT operations by treating "infrastructure as code." DevOps teams typically implement practices summarised by the colloquial directive to "eat your own dogfood;" meaning that software tools developed by a team should be used internally rather thrown over the fence to operations or users. We present a brief overview of how DevOps techniques bring proven software engineering practices to IT operations. We then discuss the application of these practices to astronomical observatories.

  14. La flore mellifère et le déclin des abeilles

    OpenAIRE

    2011-01-01

    Les actes de ce colloque reprennent les interventions présentées par les équipes de recherche sur l’abeille de Roumanie et de France. Ce colloque s’inscrit dans le cadre de l'Atelier Scientifique Franco-Roumain "La diversité des plantes mellifères et le déclin des abeilles" qui s'est tenu du 22 au 24 juin 2001 à Bucarest.

  15. Implementation and Analysis of DEVS Activity-Tracking with DEVSimPy

    OpenAIRE

    Santucci J.F.; Capocchi L.

    2013-01-01

    This paper deals with the implementation of Activity-Tracking (AT) paradigm in the DEVSimPy environment. DEVSimPy has been developed at the SPE UMR CNRS6134 (University of Corsica) in order to facilitate the modeling and the simulation of discrete-event systems described with the DEVS formalism. The AT paradigm is increasingly being used by DEVS modelers for example to improve structural aspects of models (modeling level) or to make simulation more efficient using distributed or parallel algo...

  16. Le déclin des abeilles, un casse-tête pour la recherche

    OpenAIRE

    Mollier, Pascale; Sarazin, Magali; Savini, Isabelle; Vaissière, Bernard; Belzunces, Luc; Le Conte, Yves

    2009-01-01

    Parmi 20 000 espèces d’abeilles présentes dans le monde, Apis mellifera est la plus répandue et celle que l’on connaît le mieux. Mais, comme ses cousines sauvages, elle est menacée de déclin. Evaluer ce phénomène, en comprendre les causes s’apparente à un vrai casse-tête pour la recherche et un enjeu pour nos sociétés dont l’alimentation dépend pour une bonne partie de la pollinisation des plantes à fleurs

  17. CoreDevRec:Automatic Core Member Recommendation for Contribution Evaluation

    Institute of Scientific and Technical Information of China (English)

    蒋竞; 贺佳欢; 陈学渊

    2015-01-01

    The pull-based software development helps developers make contributions flexibly and effciently. Core members evaluate code changes submitted by contributors, and decide whether to merge these code changes into repositories or not. Ideally, code changes are assigned to core members and evaluated within a short time after their submission. However, in reality, some popular projects receive many pull requests, and core members have di昋culties in choosing pull requests which are to be evaluated. Therefore, there is a growing need for automatic core member recommendation, which improves the evaluation process. In this paper, we investigate pull requests with manual assignment. Results show that 3.2%∼40.6% of pull requests are manually assigned to specific core members. To assist with the manual assignment, we propose CoreDevRec to recommend core members for contribution evaluation in GitHub. CoreDevRec uses support vector machines to analyze different kinds of features, including file paths of modified codes, relationships between contributors and core members, and activeness of core members. We evaluate CoreDevRec on 18 651 pull requests of five popular projects in GitHub. Results show that CoreDevRec achieves accuracy from 72.9% to 93.5% for top 3 recommendation. In comparison with a baseline approach, CoreDevRec improves the accuracy from 18.7% to 81.3% for top 3 recommendation. Moreover, CoreDevRec even has higher accuracy than manual assignment in the project TrinityCore. We believe that CoreDevRec can improve the assignment of pull requests.

  18. Activity Diagrams for DEVS Models: A Case Study Modeling Health Care Behavior

    Energy Technology Data Exchange (ETDEWEB)

    Ozmen, Ozgur [ORNL; Nutaro, James J [ORNL

    2015-01-01

    Discrete Event Systems Specification (DEVS) is a widely used formalism for modeling and simulation of discrete and continuous systems. While DEVS provides a sound mathematical representation of discrete systems, its practical use can suffer when models become complex. Five main functions, which construct the core of atomic modules in DEVS, can realize the behaviors that modelers want to represent. The integration of these functions is handled by the simulation routine, however modelers can implement each function in various ways. Therefore, there is a need for graphical representations of complex models to simplify their implementation and facilitate their reproduction. In this work, we illustrate the use of activity diagrams for this purpose in the context of a health care behavior model, which is developed with an agent-based modeling paradigm.

  19. Hybrid system modeling using the parallel devs formalism and the modelica language

    OpenAIRE

    Sanz Prat, Victorino

    2010-01-01

    El principal objetivo de la presente tesis doctoral es facilitar la descripción, mediante el formalismo DEVS Paralelo y el paradigma del modelado orientado al proceso, y empleando el lenguaje Modelica, de modelos de eventos discretos y de la parte de eventos discretos de modelos DAE-híbridos. El objetivo, por tanto, no sólo es facilitar que pueda emplearse Modelica para describir modelos DEVS Paralelo y orientados al proceso. Además, deben desarrollarse los modelos en Mode...

  20. Initial Service Provider DevOps concept, capabilities and proposed tools

    OpenAIRE

    John, Wolfgang; Meirosu, Catalin; Sköldström, Pontus; Nemeth, Felician; Gulyas, Andras; Kind, Mario; Sharma, Sachin; Papafili, Ioanna; Agapiou, George; Marchetto, Guido; Sisto, Riccardo; Steinert, Rebecca; Kreuger, Per; Abrahamsson, Henrik; Antonio MANZALINI

    2015-01-01

    This report presents a first sketch of the Service Provider DevOps concept including four major management processes to support the roles of both service and VNF developers as well as the operator in a more agile manner. The sketch is based on lessons learned from a study of management and operational practices in the industry and recent related work with respect to management of SDN and cloud. Finally, the report identifies requirements for realizing SP-DevOps within an combined cloud and tr...

  1. Towards an automatic model transformation mechanism from UML state machines to DEVS models

    Directory of Open Access Journals (Sweden)

    Ariel González

    2015-08-01

    Full Text Available The development of complex event-driven systems requires studies and analysis prior to deployment with the goal of detecting unwanted behavior. UML is a language widely used by the software engineering community for modeling these systems through state machines, among other mechanisms. Currently, these models do not have appropriate execution and simulation tools to analyze the real behavior of systems. Existing tools do not provide appropriate libraries (sampling from a probability distribution, plotting, etc. both to build and to analyze models. Modeling and simulation for design and prototyping of systems are widely used techniques to predict, investigate and compare the performance of systems. In particular, the Discrete Event System Specification (DEVS formalism separates the modeling and simulation; there are several tools available on the market that run and collect information from DEVS models. This paper proposes a model transformation mechanism from UML state machines to DEVS models in the Model-Driven Development (MDD context, through the declarative QVT Relations language, in order to perform simulations using tools, such as PowerDEVS. A mechanism to validate the transformation is proposed. Moreover, examples of application to analyze the behavior of an automatic banking machine and a control system of an elevator are presented.

  2. Le Déclin de l’intelligentsia de gauche en Irak

    Directory of Open Access Journals (Sweden)

    Salaam Yousif

    2007-07-01

    Full Text Available Durant les années 1940 et 1950, l’intelligentsia de gauche a joué un rôle remarquable dans la construction d’une culture irakienne vibrante, a contribué à la floraison de la littérature et des arts et a exercé une influence majeure dans les sphères politique et culturelle. Cet article se centre principalement sur les années 1960 quand, malgré deux coups d’État baassistes, l’atmosphère culturelle était clairement de gauche. La seconde moitié de la décennie a été marquée par un élan vers la gauche, par un esprit de rébellion au sein de l’intelligentsia et par des productions culturelles innovantes. Le contrôle du Baas sur la culture après 1968 et sa campagne contre le parti communiste irakien à la fin des années 1970, entre autres facteurs, ont conduit au déclin du PCI et à la réduction du rôle de l’intelligentsia de gauche.

  3. Teaching DevOps and Cloud Computing using a Cognitive Apprenticeship and Story-Telling Approach

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak

    2016-01-01

    DevOps is a new way of developing software that is challenging from a teaching perspective. In this paper, we outline these challenges and propose teaching methods that focus on skill acquisition and technical practices that focus on performant virtualization to overcome them. We describe central...... elements from our course Cloud Computing and Architecture that has been designed and executed upon these methods and practices and report our experiences and lessons learned....

  4. Structure-function analysis of the ATP-driven glycolipid efflux pump DevBCA reveals complex organization with TolC/HgdD.

    Science.gov (United States)

    Staron, Peter; Forchhammer, Karl; Maldener, Iris

    2014-01-31

    In Gram-negative bacteria, trans-envelope efflux pumps have periplasmic membrane fusion proteins (MFPs) as essential components. MFPs act as mediators between outer membrane factors (OMFs) and inner membrane factors (IMFs). In this study, structure-function relations of the ATP-driven glycolipid efflux pump DevBCA-TolC/HgdD from the cyanobacterium Anabaena sp. PCC 7120 were analyzed. The binding of the MFP DevB to the OMF TolC absolutely required the respective tip-regions. The interaction of DevB with the IMF DevAC mainly involved the β-barrel and the lipoyl domain. Efficient binding to DevAC and TolC, substrate recognition and export activity by DevAC were dependent on stable DevB hexamers. PMID:24361095

  5. ClinLabGeneticist: a tool for clinical management of genetic variants from whole exome sequencing in clinical genetic laboratories.

    Science.gov (United States)

    Wang, Jinlian; Liao, Jun; Zhang, Jinglan; Cheng, Wei-Yi; Hakenberg, Jörg; Ma, Meng; Webb, Bryn D; Ramasamudram-Chakravarthi, Rajasekar; Karger, Lisa; Mehta, Lakshmi; Kornreich, Ruth; Diaz, George A; Li, Shuyu; Edelmann, Lisa; Chen, Rong

    2015-01-01

    Routine clinical application of whole exome sequencing remains challenging due to difficulties in variant interpretation, large dataset management, and workflow integration. We describe a tool named ClinLabGeneticist to implement a workflow in clinical laboratories for management of variant assessment in genetic testing and disease diagnosis. We established an extensive variant annotation data source for the identification of pathogenic variants. A dashboard was deployed to aid a multi-step, hierarchical review process leading to final clinical decisions on genetic variant assessment. In addition, a central database was built to archive all of the genetic testing data, notes, and comments throughout the review process, variant validation data by Sanger sequencing as well as the final clinical reports for future reference. The entire workflow including data entry, distribution of work assignments, variant evaluation and review, selection of variants for validation, report generation, and communications between various personnel is integrated into a single data management platform. Three case studies are presented to illustrate the utility of ClinLabGeneticist. ClinLabGeneticist is freely available to academia at http://rongchenlab.org/software/clinlabgeneticist . PMID:26338694

  6. Implementation and Analysis of DEVS Activity-Tracking with DEVSimPy

    Directory of Open Access Journals (Sweden)

    Santucci J.F.

    2013-01-01

    Full Text Available This paper deals with the implementation of Activity-Tracking (AT paradigm in the DEVSimPy environment. DEVSimPy has been developed at the SPE UMR CNRS6134 (University of Corsica in order to facilitate the modeling and the simulation of discrete-event systems described with the DEVS formalism. The AT paradigm is increasingly being used by DEVS modelers for example to improve structural aspects of models (modeling level or to make simulation more efficient using distributed or parallel algorithm (simulation level. Although DEVSimPy can be used as a software providing some features reusable for the implementation of AT paradigm (simulation profiling or step-by-step simulation, the object oriented way used to develop DEVSimPy makes it a powerful tool to implement AT paradigm in a generic manner. DEVSimPy may be viewed as an experimental framework allowing the implementation of new AT techniques while opening up new perspectives in the field of activity modeling and simulation theory.

  7. Aynı Hastada Oluşan Santral ve Periferal Dev Hücreli Granüloma Olgusu

    OpenAIRE

    Sümer, A.Pınar; SÜMER, Mahmut; Telcioğlu, N.Tuba; Çelenk, Peruze; Günhan, Ömer

    2011-01-01

    Dev hücreli granüloma, bazen neoplazmlar gibi agresif davranış gösterse de, nonneoplastik bir lezyon olarak kabul edilmektedir. Santral ve periferal dev hücreli granüloma ile ilgili pek çok çalışma vardır. Bununla birlikte ikisinin birden aynı hastada bulunduğubir olgu henüz rapor edilmemiştir. Sunulan bu olgu raporunda, aynı hastada oluşan santral ve periferal dev hücreli granülomalar iki lezyon arasında bir ilişki olabileceği fikrini verebilir. İleride yapılacak benzer olgu raporları da bu ...

  8. Uso de DevC++® con Delmia Quest® para Optimizar Simulaciones

    Directory of Open Access Journals (Sweden)

    Ricardo Pérez Rodríguez

    2014-01-01

    Full Text Available En este artículo se presentan los elementos básicos e imprescindibles utilizados para lograr comunicación entre cualquier algoritmo de optimización que se programe en el entorno de programación DevC++ ® y que sea utilizado para optimizar modelos de simulación en Delmia Quest ® versión R19 o superiores. El objetivo de este artículo es facilitar el aprendizaje para comunicar ambas plataformas con el fin de sistematizar y automatizar la evaluación de las soluciones desde un punto de vista práctico. El aporte central de este artículo es el desarrollo y validación de un tutorial para demostrar el proceso de intercomunicación entre Delmia Quest ® y DevC++ ® . La idea global se refiere a construir un procedimiento que enlaza las instrucciones del algoritmo de optimización programado en DevC++ ® la cuales son ejecutadas por el lenguaje de simulación Delmia Quest ® , el cual devuelve algún parámetro con la información pertinente de nuevo al algoritmo de optimización. El procedimiento se repite iterativamente de acuerdo a las especificaciones del algoritmo de optimización. Con el presente tutorial, los usuarios podrán iniciar rápidamente la programación de sus propias rutinas de comunicación inclusive en otros lenguajes de programación como Java ® ahorrado recursos en costosos cursos de capacitación. Finalmente, 10 estudiantes de ingeniería probaron la efectividad del documento, al menos 50% de ellos consumieron entre 12 y 17 minutos para terminar exitosamente la programación del tutorial propuesto, donde tradicionalmente como factor barrera se pueden requerir horas e inclusive días ya que no existe bibliografía accesible y clara en el idioma español.

  9. Association between CMMI-DEV 1.2 AND ISO/TS 16949

    Directory of Open Access Journals (Sweden)

    Altamar Urbanetz de Araújo Albanez

    2014-05-01

    Full Text Available The automotive sector is one of the most daring in terms of quality, requiring ISO/TS 16949 certification. Nevertheless, there are companies those lose their certification or develop only some improvements due to a lack of enough maturity to maintain it and gaps in continuous improvement guidelines. Whereas CMMI is one of the diagnostic methods of maturity, the aim of this work is to identify the feasibility of linking the ISO/TS 16949 with the CMMI-DEV 1.2. The method used consists in review PDPs, quality certification and process maturity and then associate these two models. The analysis concludes that a company certified by ISO/TS not necessarily even reaches the maturity level 2 in CMMI. Moreover, while the CMMI model shows those items not covered and demand their development, ISO/TS only encourages "continuous improvement" without a plan or diagnostics for the company operationally achieve it.

  10. Clin Pharmacol Ther

    OpenAIRE

    Seiter, A

    2009-01-01

    "Counterfeit Drugs Kill" is the slogan the World Health Organization (WHO) uses in its anti-counterfeiting campaign. International organizations, governments of developed and developing countries, and the pharmaceutical industry created the IMPACT initiative (International Medical Products Anti-Counterfeiting Taskforce) to take on the thriving illegal industry that makes profits by selling fake drugs. However, before committing resources, policy makers want to assess the burden caused by coun...

  11. The hard way to virtual machine administration: towards DevOps : A bridge between developers and IT operators

    OpenAIRE

    Rodríguez, Christian Adrián; Molinari, Lía; Díaz, Francisco Javier

    2013-01-01

    The coexistence of multiple platforms and the implementation of different virtualization models makes server administration more complex every day. The undeniable benefits both methodologies offer in terms of performance optimization and energy saving can be overshadowed if clear guidelines are not established for configuration and maintenance in accordance with the needs of increasingly agile development models that demand quick responses. DevOps is a possible solution to this situation. How...

  12. Decreased C3 Activation by the devR Gene-Disrupted Mycobacterium tuberculosis Strain in Comparison to the Wild-Type Strain

    Directory of Open Access Journals (Sweden)

    V. Narayan Rao

    2013-01-01

    Full Text Available Activation of the complement component C3 is an important step in the complement cascade, contributing to inflammatory mechanisms. Considerable research on gene-disrupted mycobacterial strains using animal models of tuberculosis infection has reported the roles of some of the mycobacterial genes during tuberculosis infection. The aim of the present study was to assess the pattern of complement activation by the devR gene-disrupted Mycobacterium tuberculosis H37Rv strain and compare with that by its wild-type strain. In vitro complement activation at the level of C3 by the gene-disrupted strain, its complemented strain, and wild-type strain was performed using solid-phase ELISA. It was observed that the ability of devR gene-disrupted M. tuberculosis H37Rv to activate C3 was significantly reduced in comparison to its wild-type strain (P<0.05. In addition, C3 activation by the complemented devR mutant strain was almost similar to that of the wild strain, which indicated that the reduced ability to activate C3 could potentially be due to the deletion of devR gene. These findings indicate that the gene devR probably aids in complement activation and contributes to the inflammatory processes during tuberculosis infection.

  13. Webová aplikace pro vzdálené modelování a simulaci na bázi DEVS

    OpenAIRE

    Gavlík, Pavel

    2013-01-01

    Práce se zabývá návrhem a realizací webové aplikace pro vzdálený přístup k nástroji Small- DEVS, implementaci formalismu DEVS. Komunikace po síti je realizována pomocí RESTful API. Webová aplikace je napsána převážně v programovacím jazyce JavaScript s využitím frameworku AngularJS. Při vývoji webové aplikace byla použita technika Test Driven Development.  This paper deals with the design and implementation of a web application for remote access to SmallDEVS, implementation of D...

  14. AOX determination in industrial waste water according to EN 1485, DEV H14. Experience with high salt freights and interfering organic matter; AOX-Bestimmungen in Industrieabwaessern nach EN 1485, DEV H14 Erfahrungen mit hohen Salzfrachten und organischen Stoerstoffen

    Energy Technology Data Exchange (ETDEWEB)

    Helmreich, B. [Technische Univ. Muenchen, Garching (Germany). Lehrstuhl und Pruefamt fuer Wasserguete- und Abfallwirtschaft

    1999-07-01

    AOX determination in industrial waste water is not always trivial on account of high salt freights or high organic loads. Interfering substances of inorganic or organic nature can cause increases or decreases of readings that often are not plausible or reproducible. In most cases the AOX enrichment step is limiting to quantitative analysis. In the present work, enrichment in two industrial waste waters was critically assessed according to EN 1485 DEV H14. In addition, experience with the enrichment method according to Dr. Lange is reported. For the elimination of high salt freights beside a low organic concentration, cleanup by means of solid-phase extraction is considered. The results suggest that the standardized procedure is not universally applicable to any type of sample. However, appropriate action can minimize flaws of enrichment and, thereby, AOX determination. (orig.) [German] Die AOX-Bestimmung aus Industrieabwaessern ist aufgrund hoher Salzfrachten oder hoher organischer Belastungen nicht immer trivial. Stoerstoffe anorganischer wie auch organischer Art koennen zu Mehr- oder Minderbefunden fuehren, die oft nicht plausibel und reproduzierbar sind. In den meisten Faellen ist der Anreicherungsschritt des AOX fuer die quantitative Analyse limitierend. In der vorliegenden Arbeit wurde die Anreicherung nach den EN 1485 DEV H14 fuer zwei Industrieabwaesser kritisch betrachtet. Zudem werden Erfahrungen mit der Anreicherungsmethode nach Dr. Lange vorgestellt. Zur Entfernung hoher Salzfrachten neben einer geringen organischen Konzentration wurde ein Clean-up mittels Festphasenextraktion betrachtet. Die Ergebnisse legen nahe, dass das genormte Verfahren nicht universell auf jeden Probentyp anwendbar ist. Durch ein gezieltes Vorgehen koennen jedoch Fehler bei der Anreicherung und damit bei der AOX-Bestimmung minimiert werden. (orig.)

  15. 基于HLA的Agent-DEVS协同仿真建模%Collaborative modeling and simulation of Agent-DEVS based on HLA

    Institute of Scientific and Technical Information of China (English)

    曹琦; 何中市; 余磊

    2011-01-01

    In order to extend the DEVS with abilities of intelligent modeling and distributed simulation, a collaborative modeling and simulation method for Agent-DEVS based on HLA was studied. The formal description of Agent-DEVS federate models based on ParalIeI-DEVS was proposed. The models ports in Agent-DEVS were translated into data objects in HLA and the structure of the models was given. The communication mechanism was analyzed. The mapping between knowledge update in Agent-DEVS and attribute update in HLA, and that between models coupling in Agent-DEVS and instances interaction in HLA, were established respectively. Finally, the modeling and simulation application for material supply in emergent disaster was put forward. The results show that the reusability of Agent-DEVS models is enhanced by HLA and the interoperability of the models is enriched by knowledge update mechanism. In addition, the autonomy and independent ability for transaction processing are improved significantly.%为实现DEVS在智能建模与分布仿真能力方面的扩充,研究了基于HLA的Agent-DEVS协同仿真建模方法.以并行DEVS为基础,提出了Agent-DEVS联邦模型的形式化描述;将Agent-DEVS模型端口转换为HLA数据对象,确定了Agent-DEVS联邦模型结构,并分析了通信机制,分别建立了Agent-DEVS的知识更新与HLA的属性更新间的映射,以及Agent-DEVS的模型耦合与HLA的实例交互间的映射;最后结合抢险救灾物资保障的仿真建模进行了应用.结果表明,HLA体系框架增强了Agent-DEVS模型的可重用性;知识更新机制丰富了Agent-DEVS模型的互操作性;同时,Agent-DEVS模型的自治性与独立事务处理能力得到了进一步提高.

  16. Study on Combat Commanding Behavior Modeling Based on DEVS%基于DEVS的作战指挥行为建模研究

    Institute of Scientific and Technical Information of China (English)

    李京; 王子明; 李冬

    2014-01-01

    针对传统计算机兵力生成(computer generated force,CGF)建模所使用的经典人工智能编程语言存在的不足,提出一种基于离散事件系统(discrete event system specification,DEVS)的作战指挥行为建模方法。从DEVS原子模型和耦合的DEVS模型对DEVS做规范介绍,统一、规范描述指挥主体的生理和心理因素如何影响作战指挥行为,建立一种包含评估模块、压力模块和行为模块的作战指挥行为模型。结果表明:该模型能很好地将指挥主体的压力和自身生理状况融入到作战指挥行为中,能较为合理地反映出在紧张对抗环境中指挥主体的实际指挥行为。%Aiming at the shortcoming of typical artificial intelligence programming language for traditional computer generated force (CGF) modeling, put forward a new modeling method of combat commanding behavior based on discrete event system specification (DEVS). From DEVS atomic model and coupling DEVS model, make a standard introduction for DEVS, and also make an unified and standard description about how the physiological and psychological factors of commander make an influence on commanding behavior, establish a commanding behavior model which including evaluation model, pressure model and behavior model. The results show that the model can combine the commander pressure and physiological state with commanding behavior, and it can reflect reasonably the commanding behavior under the circumstance full of nervousness and confrontation.

  17. Proceedings of the INCO-DEV International Workshop on Policy Options for the Sustainable Use of Coral Reefs and Associated Ecosystems

    OpenAIRE

    2001-01-01

    The present report contains the proceedings of the INCO-DEV International Workshop on “Policy Options for the Sustainable Use of Coral Reefs and Associated Ecosystems” convened in Mombasa, Kenya, 19-22 June 2000. It was convened to address issues associated with the ongoing degradation of coral reefs and associated ecosystems. This degradation takes place inspite of an impressing body of research results and and increasing number of technical solutions becoming available. Policy ...

  18. Analysing inter-relationships among water, governance, human development variables in developing countries: WatSan4Dev database coherency analysis

    Science.gov (United States)

    Dondeynaz, C.; Carmona Moreno, C.; Céspedes Lorente, J. J.

    2012-01-01

    The "Integrated Water Resources Management" principle was formally laid down at the International Conference on Water and Sustainable development in Dublin 1992. One of the main results of this conference is that improving Water and Sanitation Services (WSS), being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation). These sectors influence or are influenced by the access to WSS. The understanding of these interrelations appears as crucial for decision makers in the water sector. In this framework, the Joint Research Centre (JRC) of the European Commission (EC) has developed a new database (WatSan4Dev database) containing 45 indicators (called variables in this paper) from environmental, socio-economic, governance and financial aid flows data in developing countries. This paper describes the development of the WatSan4Dev dataset, the statistical processes needed to improve the data quality; and, finally, the analysis to verify the database coherence is presented. At the light of the first analysis, WatSan4Dev Dataset shows the coherency among the different variables that are confirmed by the direct field experience and/or the scientific literature in the domain. Preliminary analysis of the relationships indicates that the informal urbanisation development is an important factor influencing negatively the percentage of the population having access to WSS. Health, and in particular children health, benefits from the improvement of WSS. Efficient environmental governance is also an important factor for providing improved water supply services. The database would be at the base of posterior analyses to better understand the interrelationships between the different indicators associated in the water sector in developing countries. A data model using the different indicators will be realised on the next phase of this research work.

  19. Analysing inter-relationships among water, governance, human development variables in developing countries: WatSan4Dev database coherency analysis

    Directory of Open Access Journals (Sweden)

    C. Dondeynaz

    2012-01-01

    Full Text Available The "Integrated Water Resources Management" principle was formally laid down at the International Conference on Water and Sustainable development in Dublin 1992. One of the main results of this conference is that improving Water and Sanitation Services (WSS, being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation. These sectors influence or are influenced by the access to WSS. The understanding of these interrelations appears as crucial for decision makers in the water sector. In this framework, the Joint Research Centre (JRC of the European Commission (EC has developed a new database (WatSan4Dev database containing 45 indicators (called variables in this paper from environmental, socio-economic, governance and financial aid flows data in developing countries.

    This paper describes the development of the WatSan4Dev dataset, the statistical processes needed to improve the data quality; and, finally, the analysis to verify the database coherence is presented.

    At the light of the first analysis, WatSan4Dev Dataset shows the coherency among the different variables that are confirmed by the direct field experience and/or the scientific literature in the domain. Preliminary analysis of the relationships indicates that the informal urbanisation development is an important factor influencing negatively the percentage of the population having access to WSS. Health, and in particular children health, benefits from the improvement of WSS. Efficient environmental governance is also an important factor for providing improved water supply services.

    The database would be at the base of posterior analyses to better understand the interrelationships between the different indicators associated in the water sector in developing countries. A data model using the different indicators will be realised

  20. Identificando Hallazgos de Mejora en Pymes de TI Utilizando un Modelo Ontológico para CMMI-DEV v1.3

    Directory of Open Access Journals (Sweden)

    J. Guadalupe Uribe Dévora

    2013-12-01

    Full Text Available Uno de los principales requisitos que deben cumplir las pymes de desarrollo de software es adoptar un estándar o modelo para garantizar la calidad de sus productos. Sin embargo, este tipo de organización, carece o no tienen procesos bien definidos. En este contexto implementar un modelo o estándar de calidad para estas organizaciones enfrenta algunos obstáculos como: gran desconocimiento sobre éstos, su adopción representa una curva de aprendizaje prolongado, las certificaciones de estos modelos o estándares para las pymes y su personal representan costos muy elevados. Por lo tanto, en este artículo se presenta una herramienta ontológica basada en el Modelo CMMI-DEV v1.3. El objetivo principal es proveer a las pymes de una herramienta que contraste sus procesos actuales obtenidos a través de un método para la extracción del conocimiento tácito versus los procesos de CMMI-DEV v1.3 para detectar posibles hallazgos de mejora e implementar mejoras en sus procesos organizacionales.

  1. La susceptibilidad magnética del batolito de Achala (Devónico, Sierra Grande de Córdoba y sus diferencias con otros granitos achalianos

    Directory of Open Access Journals (Sweden)

    Silvana E. Geuna

    2008-09-01

    Full Text Available El magmatismo devónico de las Sierras Pampeanas de Córdoba y San Luis está representado por batolitos y plutones de composición monzogranítica y forma subelíptica, emplazados en un basamento metamórfico-plutónico eopaleozoico. Se distinguen dos grupos: el primero, compuesto por granitoides con hornblenda-biotita, metaluminosos a débilmente peraluminosos; y el segundo, formado por granitoides con biotita y muscovita, peraluminosos. Ambos grupos se caracterizan respectivamente por tener magnetita e ilmenita como fases accesorias, lo cual genera propiedades magnéticas distintivas. Entre ellos, el batolito de Achala, Córdoba, con una extensión de casi 2.500 km², es un buen exponente de los granitos paramagnéticos (no magnéticos. Su mineralogía magnética fue caracterizada en cuarenta y un sitios, la mayoría de ellos en el Monzogranito Achala. Se determinó una susceptibilidad magnética promedio muy baja, 15 x 10-5 (SI, controlada por el contenido de biotita e ilmeno- hematita. Veintiún sitios mostraron remanencia magnética estable portada por hematita, que aparece como un mineral accesorio, intercrecida con discos de exsolución de (hemoilmenita. La anisotropía de susceptibilidad magnética es débil y predominan las formas obladas, como es usual en fábricas magmáticas de granitos paramagnéticos; casi no se obtuvieron lineaciones. El grado de anisotropía es mayor en zonas con cizallamiento magmático, debido al efecto de la deformación subsolidus. El magnetismo débil del monzogranito de Achala contrasta con el carácter magnético de los plutones monzograníticos porfíricos más representativos de otros batolitos de la región, como Renca, Cerro Áspero y Las Chacras-Piedras Coloradas. La virtual ausencia de magnetita, junto con la presencia de ilmeno-hematita exsuelta, indica que un enfriamiento bajo condiciones oxidantes sería el responsable del carácter paramagnético de Achala. Como consecuencia de aplicación pr

  2. Ivan Grohar and Oskar Dev – An Interdisciplinary and Multidisciplinary Fragment Comparison of Their Artistic Works in Škofja Loka/Slovenia (1905-1911

    Directory of Open Access Journals (Sweden)

    Franc Križnar

    2014-12-01

    Full Text Available The new Grohar’s room in the Škofja Loka Mu¬seum that is located in a more than a thousand years old town, some kilometres northwest of Ljubljana, Slove¬nia, represents one of the new possibilities to popularize old local history. Ivan Grohar (1867−1911 is one of the four well-known Slovenian painters from the beginning of the 20th century, together with Rihard Jakopič, Matija Jama and Matej Sternen. These Slovenian painters are the founders of Impressionism within the modern style. Škofja Loka became the so called Slovenian “Barbizon” (i.e. French village near Fontainebleau, once the settle-ment of painters and this art and old tradition inspired another Slovenian (music artist Oskar Dev (1868−1932, who composed some of his musical works (songs and choirs in Škofja Loka, too. His and Grohar’s period in Škofja Loka resulted in some extraordinary art works i.e. paintings and musical works. They both were inspired by the countryside that reflected on their works. This is now one of the new Slovenian’s challenges of museology and musicology in an interdisciplinary and multidisciplinary approach so the art of painting and music could be a benefit for the visitors of this and other museums.

  3. Spoločenstvá suchozemských mäkkýšov severnej časti Devínskej Kobyly (Malé Karpaty

    Directory of Open Access Journals (Sweden)

    Jozef Šteffek

    2005-11-01

    Full Text Available Present paper is focused on two topics. First topic is focused on evaluation of mollusc assemblages of northern part of the Devínska Kobyla hill (Malé Karpaty Mts.. The second topic was evaluation of all published data on molluscs of this area. The research was conducted during vegetation period of the year 1978. From 9 types of biotopes altogether 47 quantitative samples were sampled. The assemblages were evaluated on the base of constancy and dominance of the species. Altogether 7913 mollusc specimens were obtained from the samples. Composition and status of the forest mollusc assemblages in northern part of the Devínska Kobyla was shown to be determined by the substratum, age of forest stand and the degree of the biotopes disturbance. The species richest assemblage was detected within old grown forest (biotope 7 and calcareous substratum. The species poorest were assemblages found within clear-cut and young stand (biotopes 5, 8. Species rich community was found also in old growth forest with quartzite substratum, however a number of steppe species is absent within this biotope. The molluscan communities of open habitats were observed only in the northern part of the Devínska Kobyla foothill area. They occur mainly within xeric degraded grassland biotopes (vacant pastures, deforested fields. Within other non-limestone substratum biotopes only species poor coenoses composed of single or e few of species occurred (biotopes 2 and 6. The exception was the natural xeric grassland biotopes, which were typical biotopes for rich community of steppe molluscs (biotope 9. Extremely rich were limestone rocks, which are in addition partially covered by forest. The rich forest land snail community together with a number of xeric species was found here (biotope 3. In second part mollusc species composition of northern and southern part of the Devínska Kobyla massive and the Devínske Hradné Bralo hill are compared. Altogether 65 mollusc species (51

  4. Spoločenstvá suchozemských mäkkýšov severnej časti Devínskej Kobyly (Malé Karpaty)

    OpenAIRE

    Jozef Šteffek

    2005-01-01

    Present paper is focused on two topics. First topic is focused on evaluation of mollusc assemblages of northern part of the Devínska Kobyla hill (Malé Karpaty Mts.). The second topic was evaluation of all published data on molluscs of this area. The research was conducted during vegetation period of the year 1978. From 9 types of biotopes altogether 47 quantitative samples were sampled. The assemblages were evaluated on the base of constancy and dominance of the species. Altogether 7913 mollu...

  5. BİR OLGU NEDENİYLE PERİFERİK DEV HÜCRELİ REPARATİF GRANÜLOM A CASE REPORT OF PERIPHERAL GIANT CELL REPARATIVE GRANULOMA

    OpenAIRE

    Seymen, Figen

    2012-01-01

    Anahtar Sözcükler : Reparatif grantilom, diastemaBu araştırmamızda granülasyon dokusu hiperplazinin etyolojisindc hangi faktörün rol oynadığı ve klinik tanı ile histopatojik tanı arasındaki ilişki saptanmaya çalışıldı.7 yaşında bir kız çocuğunda üst orta kesici dişler arasında diastemaya neden olan bir periferik dev hücreli reparatif granuloma olgusu klinik ve patolojik olarak incelendi ve varolan diastemanın ensizyondan ve doku iyileşmesinden sonra hızla kapandığı gözlendi.Key Words : Repara...

  6. La communication sociale : une perspective de l’Église catholique ? Jean Devèze et la critique de la notion de « communication sociale »

    OpenAIRE

    Douyère, David

    2015-01-01

    La notion protéiforme de « communication sociale » a fait très tôt discussion. Lors du IIe congrès de la Société française des sciences de l’information et de la communication (Sfsic), en 1980, le chercheur Jean Devèze y a vu un réemploi inconscient d’une notion qu’il pense forgée par l’Église catholique, au moment du concile Vatican II. C’est en effet avec le décret Inter Mirifica (1963) que le terme est employé par Rome pour désigner les « mass media » et encourager les laïcs, les prêtres, ...

  7. Geología y petrología del granito tres cerritos, extremo meridional de la sierra de Quilmes y su relación con el magmatismo devónico-carbonífero de las sierras Pampeanas

    Directory of Open Access Journals (Sweden)

    Ana E Acosta Nagle

    2014-09-01

    Full Text Available El Granito Tres Cerritos está ubicado en el extremo SE de la Sierra de Quilmes, en el departamento Santa María, provincia de Catamarca, en el ambiente morfoestructural de Sierras Pampeanas Septentrionales. El basamento metamórfico de la zona de estudio está constituido por esquistos de bajo y mediano grado metamórfico pertenecientes al Complejo Tolombón, que son afectadas por una faja de cizalla formada con anterioridad al emplazamiento del intrusivo. Localmente se produce metamorfismo de contacto con formación de porfiroblastos de cordierita y biotita. El granito Tres Cerritos aflora en dos sectores, uno de mayor extensión, de unos 6 km² de superficie, de forma elongada con su eje mayor de 4 km de rumbo submeridional y otro más pequeño, que aflora al oeste del área de estudio, de unos 1,9 Km de largo por 250 m de ancho, aproximadamente. Composicionalmente varía entre sienogranito y monzogranito y presenta tres facies: Porfírica biotítica, porfírica moscovítica y equigranular moscovítica. Geoquímicamente se define como un granito calco-alcalino y peraluminoso, con alto potasio. Según dataciones K/Ar este granito sería de edad carbonífera superior. Las características petrográficas, geoquímicas y geocronológicas del granito Tres Cerritos son similares a la de los intrusivos devónico-carboníferos de las Sierras Pampeanas de Catamarca, La Rioja, Córdoba y San Luis, por lo que el granito Tres Cerritos formaría parte de un evento magmático de gran extensión areal, post-orogénico o de intraplaca, que afectó a las Sierras Pampeanas durante el Devónico-Carbonífero.

  8. Point of Care Tools im Vergleich des Universitätsklinikums Hamburg-Eppendorf (UKE: UpToDate, ClinicalResource@Ovid/Clin-eguide und Dynamed / Point of Care Tools in comparison at the University Medical Center Hamburg-Eppendorf: UpToDate, ClinicalResource@Ovid and Dynamed

    Directory of Open Access Journals (Sweden)

    Menn, Elke

    2006-09-01

    Full Text Available Point of Care Tools are used for clinical decision making – UpToDate is also used in continuing medical education. These databases compile only evidence-based knowledge which is updated regularly. Using Point of Care Tools promises to improve clinical outcomes. UpToDate has been used at the University Hospital Hamburg-Eppendorf for the last four years. In a recent trial the use of ClinicalResource@Ovid/Clin-eguide and Dynamed has been evaluated in comparison with UpToDate.

  9. Forcecom Developer Certification Handbook (DEV401)

    CERN Document Server

    Kabe, Siddhesh

    2012-01-01

    A practical guide that will help you discover fundamentals for building applications on Force.com without writing a single line of code. If you are new to the Force.com platform and want to learn from scratch, it is advisable that you begin with the first chapter and move on to the last. However, if you are familiar with Force.com and want to understand in detail some aspect of it, you can dip into any chapter. Each certification module is covered in a separate chapter, and is accompanied by questions being asked in the exams. Developers who need to prepare for the Salesforce.com Certified For

  10. ComDev in the Mediatized World

    DEFF Research Database (Denmark)

    Tufte, Thomas; Hemer, Oscar

    In late 2011 we are in the beginning of a revolution that may or may not turn out to be more far-reaching than the one unleashed in 1989. A common denominator in this resurging revolution is the mobilizing power of the so-called social media. Even if labels such as the Twitter or Facebook revolut...

  11. Disease: H00256 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ndromes. Endocr Dev 13:99-116 (2008) PMID:17161331 Metherell LA, Chan LF, Clark AJ The genetics of ACTH resistance syndromes. Best Pract Res Clin Endocrinol Metab 20:547-60 (2006) ...

  12. Point-of-Care Healthcare Databases Are an Overall Asset to Clinicians, but Different Databases May Vary in Usefulness Based on Personal Preferences. A Review of: Chan, R. & Stieda, V. (2011. Evaluation of three point-of-care healthcare databases: BMJ Point-of-Care, Clin-eguide and Nursing Reference Centre. Health and Information Libraries Journal, 28(1, 50-58. doi: 10.1111/j.1471-1842.2010.00920.x

    Directory of Open Access Journals (Sweden)

    Carol D. Howe

    2011-01-01

    Full Text Available Objective – To evaluate the usefulness of three point-of-care healthcare databases (BMJ Point-of-Care, Clin-eguide, and Nursing Reference Centre in clinical practice.Design – A descriptive study analyzing questionnaire results.Setting – Hospitals within Alberta, Canada’s two largest health regions (at the time of this study, with a third health region submitting a small number of responses.Subjects – A total of 46 Alberta hospital personnel answered the questionnaire, including 19 clinicians, 7 administrators, 6 nurses, 1 librarian, 1 preceptor, and “some” project coordinators. Subjects were chosen using a non-probability sampling method.Methods – The researchers developed an online questionnaire consisting of 17 questions and posted it on the University of Calgary’s Health Sciences Library and the Health Knowledge Network websites. The questions, in general, asked respondents how easy the databases were to search and use, whether the database content answered their clinical questions, and whether they would recommend the databases for future purchase. Most questions required a response for each of the three databases. The researchers collected quantitative data by using a Likert scale from 1 to 5, with 5 being the most positive answer and 1 being the most negative. They collected qualitative data by asking open-ended questions.Main Results – With regard to ease of searching, BMJ Point-of-Care (BMJ received the greatest number of responses (71% at level 5. A smaller number of respondents (56% rated Nursing Reference Centre (NRC at level 5. Clin-eguide received 59% of the responses at level 5, but it also received the greatest number of responses at the next highest level (level 4. Respondents rated all three databases similarly with regard to levels 1 and 2.Regarding how easy the resources were to learn, most respondents rated all three databases as easy to learn (BMJ, 77%; Clin-eguide, 72%; and NRC, 68%. Very few respondents

  13. Anal bölgede malign dev kondilom

    OpenAIRE

    Baydar, B; Yılmaz, Y.; Kamer, E; Alper, E.; Örmeci, B; Aslan, F; Tarcan, E; Ermete, M.

    2010-01-01

    Human Papilloma Virus (HPV) infection is one of the most common sexually transmitted disease. In this study, 50 years old male patient is presented with a growing mass in anal region for 6 years. Surgical exicision was performed with a giant anal condyloma diagnose and squamose cell carcinoma in few areas was reported in pathology specimen, radiotheraphy was performed in the postoperative period. There was no recurrence in six months period. As a result, surgery is an effective theraphy f...

  14. Over’de Dev Basit Seröz Kist

    OpenAIRE

    KÖKÇÜ, A.; ÇOKŞENİM, Ş.; KANDEMİR, B.

    2010-01-01

    SUMMARY Huge Simple Serous Cyst of Ovary A 22.5 kg. ovarian serous cyst, the largest ovarian tumor diagnosed up to now in our hospital has been presented. The relevant literature was reviewed. Özet Şimdiye kadar hastanemizde tanımlanmış en büyük över tümörü olan 22.5 kg. ağırlığında ovarian basit seröz kist olgusu sunuldu. Konu ile ilgili literatür incelendi.

  15. Pilkupüüdev seltsidaam / Aare Ermel

    Index Scriptorium Estoniae

    Ermel, Aare, 1957-2013

    2006-01-01

    Shoti päritolu näitlejanna Lindsay Duncan, kes kehastab ajaloolises teleseriaalis "Rooma" (tootjad Ameerika HBO, inglaste BBC ja itaallaste RAI) Gaius Julius Caesari kättemaksuhimulist armukest Serviliat. Sama ka : Teleleht nr. 50, lk.38 : ill

  16. La susceptibilidad magnética del batolito de Achala (Devónico, Sierra Grande de Córdoba y sus diferencias con otros granitos achalianos The magnetic susceptibility of the Achala Batholith (Devonian, Sierra Grande de Córdoba and its difference with other Achalian granites

    Directory of Open Access Journals (Sweden)

    Silvana E. Geuna

    2008-09-01

    Full Text Available El magmatismo devónico de las Sierras Pampeanas de Córdoba y San Luis está representado por batolitos y plutones de composición monzogranítica y forma subelíptica, emplazados en un basamento metamórfico-plutónico eopaleozoico. Se distinguen dos grupos: el primero, compuesto por granitoides con hornblenda-biotita, metaluminosos a débilmente peraluminosos; y el segundo, formado por granitoides con biotita y muscovita, peraluminosos. Ambos grupos se caracterizan respectivamente por tener magnetita e ilmenita como fases accesorias, lo cual genera propiedades magnéticas distintivas. Entre ellos, el batolito de Achala, Córdoba, con una extensión de casi 2.500 km², es un buen exponente de los granitos paramagnéticos (no magnéticos. Su mineralogía magnética fue caracterizada en cuarenta y un sitios, la mayoría de ellos en el Monzogranito Achala. Se determinó una susceptibilidad magnética promedio muy baja, 15 x 10-5 (SI, controlada por el contenido de biotita e ilmeno- hematita. Veintiún sitios mostraron remanencia magnética estable portada por hematita, que aparece como un mineral accesorio, intercrecida con discos de exsolución de (hemoilmenita. La anisotropía de susceptibilidad magnética es débil y predominan las formas obladas, como es usual en fábricas magmáticas de granitos paramagnéticos; casi no se obtuvieron lineaciones. El grado de anisotropía es mayor en zonas con cizallamiento magmático, debido al efecto de la deformación subsolidus. El magnetismo débil del monzogranito de Achala contrasta con el carácter magnético de los plutones monzograníticos porfíricos más representativos de otros batolitos de la región, como Renca, Cerro Áspero y Las Chacras-Piedras Coloradas. La virtual ausencia de magnetita, junto con la presencia de ilmeno-hematita exsuelta, indica que un enfriamiento bajo condiciones oxidantes sería el responsable del carácter paramagnético de Achala. Como consecuencia de aplicación pr

  17. Disease: H00098 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00098 Chronic granulomatous disease, including the following four diseases: X-link...65 Kumar A, Teuber SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immu...ifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of I

  18. Disease: H00087 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00087 Other humoral immunodeficiencies, including the following three diseases: Im...MeSH: C537362 PMID:11058677 (description, gene) Buckley RH. Primary immunodeficiency diseases due to defects...win ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immun...C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of Immunol

  19. Disease: H00089 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00089 IFN-gamma/IL-12 axis, including the following five diseases: IL-12 p40 subun...rrent perspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:18424339 (ge...R, Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of Immunological So

  20. PAEDIATRIC POSTERIOR FOSSA TUMORS: A CLIN ICO - PATHOLOGICAL STUDY I N A TERTIARY CARE HOSPITAL

    Directory of Open Access Journals (Sweden)

    Raja Sekhar Kennedy

    2015-09-01

    Full Text Available INTRODUCTION: Tumors of the Central Nervous S ystem , are the second commonest childhood tumors and are the most common solid paediatric tumors comprising 40% - 50% of all tumors . 1 2 Posterior fossa brain tumors are one of the most devastating forms of human illnesses wh ich are more common in children. AIMS AND OBJECTIVES : To study the incidence, clinicopathological features and management of paediatric posterior fossa tumors. MATERIALS AND METHOD S : This is a prospective study done in the Department of Neurosurgery, Ranga raya Medical College, Government General Hospital, Kakinada from 2012 to 2015. It is a Tertiary Care Hospital. A total of 25 paediatric patients ranging from infants to 15 years were included in the study. DISCUSSION AND CONCL USION: Posterior fossa tumors are the commonest solid brain tumors of children with a rate of 2.4 per lakh of children at risk per year. The predominant symptoms are headache and vomiting followed by cerebellar symptoms (gait disturbances. Posterior fossa tumors are predominantly seen in children with peak incidence in first decade. Commonest presenting symptoms are due to raised intracranial pressure with headache and vomiting followed by cerebellar symptoms. Meticulous microsurgical techniques are to be followed in removing these tum ors. The incidence of recurrence is very less after gross total excision. Prognosis is good in patients with total excision

  1. Le Déclin de l’intelligentsia de gauche en Irak

    OpenAIRE

    Salaam Yousif

    2012-01-01

    Durant les années 1940 et 1950, l’intelligentsia de gauche a joué un rôle remarquable dans la construction d’une culture irakienne vibrante, a contribué à la floraison de la littérature et des arts et a exercé une influence majeure dans les sphères politique et culturelle. Cet article se centre principalement sur les années 1960 quand, malgré deux coups d’État baassistes, l’atmosphère culturelle était clairement de gauche. La seconde moitié de la décennie a été marquée par un élan vers la gau...

  2. Disease: H00104 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ctor D into Ba and Bb. Hydrolyzed C3Bb is responsible for a constant low level of C3 cleavage into C3b. If C...H00104 Alternative complement pathway component defects, including the following four disea...primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:17952897 (gene) Geha RS, Notarange...hs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the Intern...ational Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee. J Allergy Clin Immunol 120:776-94 (2007) ...

  3. Disease: H01362 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 0: L13.0 PMID:22811741 (gene, env_factor) Nakajima K Recent advances in dermatitis herpetiformis. Clin Dev I..., Hissa-Elian A, de Abreu MA, Goncalves VS Review: dermatitis herpetiformis. An Bras Dermatol 88:594-9 (2013...76 (drug) Caproni M, Antiga E, Melani L, Fabbri P Guidelines for the diagnosis and treatment of dermatitis herpetiformis. J Eur Acad Dermatol Venereol 23:633-8 (2009) ...

  4. Disease: H00105 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00105 Mannose-binding lectin pathway component defects, including the following two diseases...ering MC, Wurzner R, Tedesco F Complement in human diseases: Lessons from complement deficiencies. Mol Immun... Kumar A, Teuber SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immuno...imary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary I..., Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Pr

  5. Disease: H00102 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00102 Classic complement pathway component defects, including the following eight diseases...h increased risk to develop systemic lupus erythematosus (SLE) and SLE-like diseases... Kumar A, Teuber SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immuno...imary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary I...pel H, Conley ME, Fischer A, Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Pr

  6. De la promotion à la relégation. Le déclin des CAP de couture

    OpenAIRE

    Divert, Nicolas

    2013-01-01

    Il y a un siècle, la naturalisation du lien entre les filles et la couture rend légitime leur orientation dans les CAP de cette spécialité. Ce faisant, elles accèdent à l’enseignement professionnel qui les maintenait à sa périphérie. Mais alors que les CAP sont construits théoriquement à partir de liens étroits avec l’emploi, des déterminants politiques, économiques ou sociaux apparaissent majeurs pour saisir la construction, l’évolution et le maintien d’une offre de formation initiale. Si ce...

  7. Which Clinical Guidelines Should Be Implemented for Management of Osteopenia in Primary Care? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Turia Hollingsworth

    2014-11-01

    Full Text Available Literature review was conducted to determine clinical guidelines for osteopenia management of immunocompetent patients in the primary care setting. It was concluded that pharmacological treatment should be offered to patients with osteopenia if they are considered high risk, which can be determined by utilizing the World Health Organization Fracture Risk Assessment Tool (FRAX® to evaluate 10-year risk. Patients with a calculated hip fracture probability of at least 3% or those with probability of 20% or more for all osteoporotic fractures may be offered bisphosphonate therapy.

  8. Should Primary Care Physicians Address Sleep to Improve Weight Loss in Obese Patients? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Kjersti E. Knox

    2015-11-01

    Full Text Available Obesity is a commonly encountered problem in the primary care setting. Simultaneously, sleep is seen to hold an increasingly important role in many components of health and wellness. A review of the literature was performed to determine if improving sleep positively impacts weight loss in obese adults. The evidence reviewed suggests that improving patients’ sleep may initially improve patient weight loss; however, current studies do not show a sustained statistically significant impact. Until higher powered and higher quality studies are completed, there are no clear evidence-based guidelines for primary care physicians to follow regarding sleep and obesity.

  9. Pro website development and operations streamlining DevOps for large-scale websites

    CERN Document Server

    Sacks, Matthew

    2012-01-01

    Pro Website Development and Operations gives you the experience you need to create and operate a large-scale production website. Large-scale websites have their own unique set of problems regarding their design-problems that can get worse when agile methodologies are adopted for rapid results. Managing large-scale websites, deploying applications, and ensuring they are performing well often requires a full scale team involving the development and operations sides of the company-two departments that don't always see eye to eye. When departments struggle with each other, it adds unnecessary comp

  10. $V_DEV$ divisore di frequenza programmabile in standard VME 6U

    CERN Document Server

    Paoluzzi, G

    1999-01-01

    Modulo a 32bit programmabile tramite bus VME, divisore di frequenza a 4 canali per segnali sinusoidali e digitali nello standard NIM, utilizzato per le frequenze di acquisizione nell¹esperimento NAUTILUS.

  11. Dev konka bülloza içinde fungus topu: Olgu sunumu,

    OpenAIRE

    Acar, A.; Uyar, M; Açıkalın, A.; E.Dursun; , S.Kurukahvecioğlu; Eryılmaz, A.

    2013-01-01

    Concha bullosa is one of the most common nasal anatomic variations. The size of concha bullosa is important factor in its symptomatic situation. Fungus ball is extramucosal and noninvasive accumulations of degenerating fungal hyphae. It is most common occur form in fungal sinusitis. The fungus ball is mostly caused by Aspergillus spp. In this case report, we present a rare fungus ball case which is localized chonca bullosa. Eight-teen years-old female patient was admitted to our clinic. She h...

  12. Integrazione dei dati di contesto nel modello matematico che utilizza le librerie DEVS

    OpenAIRE

    Capocchi, Laurent; Santucci, Jean François

    2013-01-01

    Le attività svolte nell’ambito dell’Azione 7.1.3 (cfr. documento “7.1.3_report_RAS”) hannoevidenziato la necessità di elaborare, per il Bacino del Rio San Gerolamo, i dati relativi allasuddivisione in sottobacini omogenei per comportamento idraulico, e i valori dei tempi dicorrivazione relativi a ciascuno di questi sottobacini.Tali dati sono infatti necessari per la calibrazione del modello matematico di simulazione delcomportamento idraulico di un bacino idrografico sul caso reale del bacino...

  13. Emblematika: knihy emblémů, impres a devíz

    Czech Academy of Sciences Publication Activity Database

    Konečný, Lubomír

    Praha : Artefactum, 2015 - (Purš, I.; Kuchařová, H.), s. 339-342 ISBN 978-80-86890-72-2 R&D Projects: GA AV ČR 1QS800330501 Institutional support: RVO:68378033 Keywords : Archduke Ferdinand II of Tyrol * emblematics * emblem books Subject RIV: AL - Art, Architecture, Cultural Heritage

  14. GENÇ ERKEK HASTADA DEV ÜRETER TAŞI: OLGU SUNUMU

    OpenAIRE

    Özkan, Burak; SANCAKLI, Özgür; DEMİRKESEN, Oktay

    2014-01-01

    Backgroud and Design.- Ureteral stones are usually small and arise from the kidney. The term giant has been applied to ureteral stones that are more than 5 cm length and/or 50 gr. or more in weight. Here in we report a case of a giant ureteral stone in a 37 year old man, presented with right flank pain referred to our clinic. Radiological examinations revealed right hydronephrosis with a giant ureteral stone. Open ureterolitotomy was performed and the stone was removed. The ureteral stone was...

  15. The sacral building with three apses at Devín: possibilities and limits of interpretation

    Czech Academy of Sciences Publication Activity Database

    Válová, Katarína

    Istanbul: Archaeology & Art Publications, 2014 - (Yilmaz, Ö.). s. 165 ISBN 978-605-396-287-8. [Annual Meeting of the European Association of Archaeologists /20./. 10.09.2014-14.09.2014, Istanbul] Institutional support: RVO:67985912 Keywords : sacral architecture * history of archaeology * political archaeology Subject RIV: AC - Archeology, Anthropology, Ethnology https://www.eaa2014istanbul.org/ assets /indirilecekler/2014%20EAA%20abstracts.pdf

  16. CloudWave: where adaptive cloud management meets DevOps

    OpenAIRE

    Bruneo, Dario; Fritz, Thomas; Keidar-Barner, Sharon; Leitner, Philipp; Longo, Francesco; Marquezan, Clarissa; Metzger, Andreas; Pohl, Klaus; Puliafito, Antonio; Raz, Danny; Roth, Andreas; Salant, Eliot; Segall, Itai; Villari, Massimo; Wolfsthal, Yaron

    2014-01-01

    The transition to cloud computing offers a large number of benefits, such as lower capital costs and a highly agile environment. Yet, the development of software engineering practices has not kept pace with this change. The design and runtime behavior of cloud based services and the underlying cloud infrastructure are largely decoupled from one another, which limits both the efficiency of the cloud environment and the Quality of Service which can be delivered to the hosted applications. This ...

  17. Asociaciones palinológicas en las formaciones Los Monos (Devónico e Itacua (Carbonífero Inferior en Balapuca (Cuenca Tarija, sur de Bolivia: Parte 2. Asociaciones de la Formación Itacuae interpretación estratigráfica y cronología de las formaciones Los Monos e Itacua Palynological assemblages present in Los Monos (Devonian and Itacua (Early Carboniferous formations at Balapuca (Tarija basin, southern Bolivia: Part 2. Itacua Formation assemblages and stratigraphical interpretation and chronology of the Los Monos and Itacua formations

    Directory of Open Access Journals (Sweden)

    Mercedes di Pasquo

    2007-07-01

    Full Text Available Se presenta el resultado palinológico de tres muestras fértiles de la Formación Itacua, la cual aflora en la localidad de Balapuca ubicada en la margen boliviana del río Bermejo, en la sierra de San Telmo. La extensión estratigráfica de las especies determinadas en esta asociación permitió identificar dos conjuntos de palinomorfos, uno autóctono compuesto por 61 especies de esporas y escasas colonias de Botryococcus, y otro conjunto de especies retrabajadas conformado por esporas, acritarcas, prasinofitas, algas clorofíceas, criptosporas y quitinozoarios, en su mayoría procedentes de capas del Devónico y subordinadas esporas del Tournaisiano (Carbonífero. Dos especies de esporas autóctonas se proponen como nuevas combinaciones. La distribución estratigráfica de especies autóctonas claves permitió asignar dicha asociación al Viséano temprano (Carbonífero Temprano. Se trata del primer trabajo donde se ¡lustran por primera vez palinomorfos de esta antigüedad (así como una selección de especies retrabajadas obtenidos de un depósito in situ de la Formación Itacua presente en la parte sur de la Cuenca Tarija. Sobre la base de la edad atribuida a las formaciones Los Monos e Itacua en este estudio, queda definido un hiato entre ellas, caracterizado por un lapso erosivo en el Frasniano-Tournaisiano y otro no depositacional durante el Famenniano tardío ('Struniano', basado en la presencia/ausencia en la asociación de la Formación Itacua de especies de palinomorfos retrabajados con extensión estratigráfica restringida. Por otra parte, sobreyacen a esta unidad sedimentitas del Grupo Macharetí datadas con palinología como del Carbonífero Tardío temprano. Entre ambas unidades se registra un nuevo hiato que abarca el Viséano tardío-Serpukhoviano interpretado en parte como no depositacional. Se incluye, además, una discusión sobre las principales causas de ambos hiatusThe palynological result of three fertile samples of

  18. Oral Kavitede Nadir Görülen Bir Benign Tümör: Dev Lingual Lipom

    OpenAIRE

    Ural, Ahmet; TI?BA?, Didem; ?MAMO?LU, Mehmet; BAHADIR, Osman; Özoran, Yavuz

    2009-01-01

    A rare benign tumor of the oral cavity: giant lingual lipoma Lipomas are among the most common benign tumors, but they occur infrequently in the oral cavity. We present a case of an enormous intraoral lipoma that seriously interferes with the speech and swallowing function. Clinical and histopathological features of oral cavity lipomas are discussed with a literature review.

  19. Drug education in victorian schools (DEVS: the study protocol for a harm reduction focused school drug education trial

    Directory of Open Access Journals (Sweden)

    Midford Richard

    2012-02-01

    Full Text Available Abstract Background This study seeks to extend earlier Australian school drug education research by developing and measuring the effectiveness of a comprehensive, evidence-based, harm reduction focused school drug education program for junior secondary students aged 13 to 15 years. The intervention draws on the recent literature as to the common elements in effective school curriculum. It seeks to incorporate the social influence of parents through home activities. It also emphasises the use of appropriate pedagogy in the delivery of classroom lessons. Methods/Design A cluster randomised school drug education trial will be conducted with 1746 junior high school students in 21 Victorian secondary schools over a period of three years. Both the schools and students have actively consented to participate in the study. The education program comprises ten lessons in year eight (13-14 year olds and eight in year nine (14-15 year olds that address issues around the use of alcohol, tobacco, cannabis and other illicit drugs. Control students will receive the drug education normally provided in their schools. Students will be tested at baseline, at the end of each intervention year and also at the end of year ten. A self completion questionnaire will be used to collect information on knowledge, patterns and context of use, attitudes and harms experienced in relation to alcohol, tobacco, cannabis and other illicit drug use. Multi-level modelling will be the method of analysis because it can best accommodate hierarchically structured data. All analyses will be conducted on an Intent-to-Treat basis. In addition, focus groups will be conducted with teachers and students in five of the 14 intervention schools, subsequent to delivery of the year eight and nine programs. This will provide qualitative data about the effectiveness of the lessons and the relevance of the materials. Discussion The benefits of this drug education study derive both from the knowledge gained by trialling an optimum combination of innovative, harm reduction approaches with a large, student sample, and the resultant product. The research will provide better understanding of what benefits can be achieved by harm reduction education. It will also produce an intervention, dealing with both licit and illicit drug use that has been thoroughly evaluated in terms of its efficacy, and informed by teacher and student feedback. This makes available to schools a comprehensive drug education package with prevention characteristics and useability that are well understood. Trial registration Australia and New Zealand Clinical Trials Register (ANZCTR: ACTRN12612000079842

  20. Disease: H00086 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available the presence of diminished IgG and IgA levels. Seventy per cent of the cases are ...H00086 Hyper IgM syndromes, autosomal recessive type, including the following three disea...tives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:18424339 (gene) Morra M, ...er A, Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency disea...ses: an update from the International Union of Immunological Societies Primary Immunodeficiency Disea

  1. Disease: H00093 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available nts a group of distinct entities characterized by defective normal or elevated IgM in the presence of diminished IgG and IgA level...H00093 Combined immunodeficiencies (CIDs), including the following nine diseases: X..., Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) ...Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the Inte...rnational Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee. J All

  2. Barrages de tufs calcaires et cascades dans le Centre-Var : rapport avec les eaux des sources karstiques, historique et déclin actuel

    Directory of Open Access Journals (Sweden)

    Jean Nicod

    2010-03-01

    Full Text Available Dans les vallées de l'intérieur de la Provence, de grandes accumulations de tufs et de travertins sont liées aux sources karstiques importantes. En rapport avec l'évolution géomorphologique, les travertins anciens forment des balcons et des terrasses. La période récente de grande construction travertineuse débute souvent au Préboréal et se généralise dans l'Atlantique. Au cours du Néolithique final, cette sédimentation décroît en fonction de la détérioration climatique et de la déforestation liée à la pression anthropique. Cependant quelques barrages (dômes stromatolitiques et marais, avec dépôts de tourbes, persistent jusqu'à l'âge historique. Dans le Centre-Var, les dépôts de tufs restent actifs dans quelques sites refuges, dans les hautes vallées forestières, proches des sources karstiques, et sur quelques grandes cascades. De plus, le long des rivières, des cascades à tufs sont issues des aménagements de moulins et de canaux d'irrigation.La sédimentation des tufs dépend de nombreux facteurs en interaction, dont :- la minéralisation carbonatée des eaux des sources karstiques,- le régime hydrologique saisonnier,- l'écosystème régional et local (forêts, ripisylves,- le biotope algo-bryophytique.De nos jours, la sédimentation stromatolitique est en situation critique du fait de l'impact de multiples facteurs en rapport avec l'accroissement de l'urbanisation et les changements environnementaux :- pollution, accroissement de la turbidité sur les petits affluents résultant de l'agriculture mécanisée,- diminution drastique des débits dans les saisons de printemps-été, où l'activité algo-bryophytique est la plus favorable, du fait de l'augmentation générale des prélèvements.La période de sécheresse récente (2006-2008 a accentué ces impacts sur les barrages de tufs. Et la protection de ces sites de grand intérêt environnemental et patrimonial pose des problèmes complexes.In the valleys of inner Provence, numerous travertine formations are wide extension in relation with important karstic springs. Because the geomorphological evolution, the old travertines are maked up balconies and terraces. The recent period of main travertine construction begins as far back as in the Preboreal (even in Bölling at southern Luberon and appears generalized in the Atlantic. In the late Neolithic (around 4000 BP, this sedimentation decreases with the climatic deterioration and the opening of forest cover under the weight of human pressure. However some tufa dams (stromatolite doms and associated wetland with peat deposits continues up to the historic times. In the Middle Var County, these tufa deposits on the dams remains active in some refuge sites, in the upper and woody valleys, near the karstic springs, and in any high waterfalls. More along the rivers, some waterfalls with tufa deposits proceeds from the old mills and irrigation canal fitting. This tufa sedimentation is in relation with the interference of multiple factors, whose:- carbonate mineralization of the karstic springs,- seasonal working of the hydrosystem,- regional and local ecosystem (forested land, important riparian cover,- algo-bryophitic biotope.Nowadays, the stromatolitc sedimentation is in critical situation because the impact of multiple factors in relation with increased urbanization and environmental change:- river pollution, increased turbidity in little tributaries flowed from agricultural mecanization,- decreased flow in seasonable times (spring - summer, the most favourable to the algo-bryophytic activity, because the common increasing water sample.The recent drought period (2006-2008 has maked worse these impacts on the tufa dams. And the protection of these sites of large environmental and patrimonial interest put complex problems.

  3. Les chaîniers français (1823-2005. De l’essor au déclin

    Directory of Open Access Journals (Sweden)

    Edgard Strigler

    2011-05-01

    Full Text Available Composition du juryMonsieur Marc de Beauregard, PDG de Sedis de 1991 à 1993,Monsieur Michel Cotte, professeur émérite, Université de Nantes,Monsieur Alain Dewerpe, directeur d’études, ÉHESS,Monsieur Patrick Fridenson, directeur de thèse, directeur d’études, ÉHESS,Monsieur Hervé Joly, directeur de recherche, CNRS,Monsieur Pierre Lamard, professeur, ,Université de Technologie de Belfort-Montbéliard,Monsieur Denis Woronoff, professeur émérite, Université de Paris I.Thèse soutenue le 20 janvier 2...

  4. Le déclin du mélodrame : les cinéastes contemporaines et la transformation du genre

    OpenAIRE

    Suárez, Juana

    2014-01-01

    Quoiqu’il réponde à des caractéristiques particulières dans chaque pays, le mélodrame est un genre fortement enraciné dans les cinémas d’Amérique latine et il a été récurrent en particulier dans l’industrie du feuilleton télévisé. Malgré des spécificités nationales, les sujets dominants ont été les drames domestiques et l’épopée nationale dont les problèmes trouvent un écho dans le microcosme familial. Dans son développement historique, le mélodrame a servi à représenter le caractère patriarc...

  5. What Are the Recommended Timing and Screening Modalities in Women at Higher Risk for Developing Breast Cancer? A Clin-IQ

    Science.gov (United States)

    Jatala, Summer; Fitzgerald, Shawn; Tietze, Pamela; Ramakrishnan, Kalyanakrishnan; McCarthy, Laine H.; Wickersham, Elizabeth

    2016-01-01

    Early detection of breast cancer is desirable to prevent progression to advanced disease. This subject has been one of significant study and debate for women at normal risk, and recommendations continue to evolve. However, with regard to women at high risk, the recommendations from various health care professional organizations, including the recent recommendations from the United States Preventative Services Task Force, are different and also inconsistent concerning when to begin screening and which modalities should be used. We review several randomized controlled trials and consensus opinions regarding when to begin screening for breast cancer and how to best screen women at high risk. Specifically, we address women with known personal history of breast cancer, prior mantle radiation, or specific family history (including genetic family history) of breast cancer. The purpose of this inquiry is to present current evidence and suggest a clinical pathway regarding the screening of women at high risk for breast cancer. PMID:26848484

  6. What Are the Recommended Timing and Screening Modalities for Women at Higher Risk of Developing Breast Cancer? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Summer Jatala

    2015-01-01

    Full Text Available Early detection of breast cancer is desirable to prevent progression to advanced disease. This subject has been one of significant study and debate for women at normal risk, and recommendations continue to evolve. However, with regard to women at high risk, the recommendations from various health care professional organizations, including the U.S. Preventive Services Task Force, are different and also inconsistent concerning when to begin screening and which modalities should be used. We review several randomized controlled trials and consensus opinions regarding when to begin screening for breast cancer and how to best screen women at high risk. Specifically, we address women with known personal history of breast cancer, prior mantle radiation or specific family history (including genetic family history of breast cancer. The purpose of this inquiry is to present current evidence and suggest a clinical pathway regarding the screening of women at high risk for breast cancer.

  7. L’essor et le déclin de la stratégie économique keynésienne – structuraliste au Mexique

    OpenAIRE

    López G., Julio

    2012-01-01

    Pendant au moins deux décennies après la seconde guerre mondiale, la croissance économique au Mexique a été très rapide, à tel point que pour la caractériser, le terme « miracle mexicain » a été introduit. Le but de ce travail est d’étudier les causes immédiates ainsi que les origines historiques de l’essoufflement du miracle mexicain. L’auteur examine les limites de la stratégie fondée sur la substitution des importations en prenant en compte aussi bien des problèmes du côté de l’offre que d...

  8. Ivan Grohar and Oskar Dev – An Interdisciplinary and Multidisciplinary Fragment Comparison of Their Artistic Works in Škofja Loka/Slovenia (1905-1911)

    OpenAIRE

    Franc Križnar

    2014-01-01

    The new Grohar’s room in the Škofja Loka Mu¬seum that is located in a more than a thousand years old town, some kilometres northwest of Ljubljana, Slove¬nia, represents one of the new possibilities to popularize old local history. Ivan Grohar (1867−1911) is one of the four well-known Slovenian painters from the beginning of the 20th century, together with Rihard Jakopič, Matija Jama and Matej Sternen. These Slovenian painters are the founders of Impressionism within the modern style. Škofja L...

  9. Evaluación del desempeño de procesos industriales utilizando redes de petri simuladas bajo el formalismo devs

    OpenAIRE

    PARRA ORTEGA, CARLOS A.

    2009-01-01

    Un aspecto fundamental de los sistemas de producción es la medida de su desempeño. Par a obtener esta medida, se recurre frecuentemente a modelos matemáticos tales como redes de Petri, con el fin de validar su comportamiento concurrente, presencia/ ausencia de bloqueos, sincronización de actividades, entre otros aspectos. A pesar de sus ventajas, el uso de redes de Petrino permite evaluar otros aspectos que son importantes en los procesos de manufactura, por tal motivo se recurre a la simu...

  10. Karşı taraf böbrek fonksiyonu kötü olan bir dev böbrek taşı olgusu

    OpenAIRE

    Isen, K; Cihan, S

    2009-01-01

    Giant renal calculus is rarely seen in urologic practice. A 69-year-old woman who had right giant renal calculus with poorly functioning opposite kidney is presented. She was with a history of right pyelolithotomy for large renal calculus 10 years back. Ultrasonography(USG), uncontrast computed tomography ( CT ), plain abdominal X-ray ( KUB ) and intraveneous urography ( IVU ) revealed a giant renal calculus (10 x 8 cm) and grade III hydronephrosis on the right kidney and moderate calixiel di...

  11. Association Between Organizational Citizenship Behavior and Educational Performance of Faculty Members in Tabriz University of Medical Sciences- 2014 [Res Dev Med Educ 2015;4(1:81-84

    Directory of Open Access Journals (Sweden)

    Asadullah Khadivi

    2015-12-01

    Results: There was a significant relationship between altruism and educational performance (P =0.043. There was a significant relationship between conscientiousness and educational performance (p=0.046. A significant relationship was observed between sportsmanship and educational performance (p=0.004. There was no significant relationship between civic virtue and educational performance (p=0.98. A significant relationship was observed between respect and educational performance (P>0.001. There was no relationship between citizenship behavior and gender of the faculty members (P> 0.05. Conclusion: The results of this study showed that the more faculty members have the spirit of cooperation and assistance to colleagues and students and try to understand the specific situations that students face, the more effective they are in increasing the educational performance at the university level.

  12. Fruits of Knowledge: Polemics, Humour and Moral Education in the Writings of Rokeya Sakhawat Hossain, Lila Majumdar and Nabaneeta Dev Sen

    NARCIS (Netherlands)

    Bagchi, B.

    2014-01-01

    This paper analyses literary sources, by three women writing in Bengali, from c.1900 to contemporary times. These writings offer far more complex, heterogeneous, innovative and creative strategies for the shaping, reform and moral education of subjects, than have hitherto been recognised. Authors fo

  13. DevOps, la nueva tendencia en el desarrollo de sistemas TI, un caso práctico en el análisis de incidencias de software

    OpenAIRE

    Jiménez Marco, Guillermo

    2016-01-01

    En el ámbito de las tecnologías de la información se requiere una respuesta cada vez más rápida a las necesidades de los clientes y a la vez un servicio que sea estable, seguro y predecible. Esto establece un compromiso entre cambio y estabilidad. Trabajar en una solución que entregue cambios de forma frecuente (como pueden ser las metodologías ágiles) sin tener en cuenta la fiabilidad en la gestión operacional o la comunicación entre desarrollo y operaciones hace que en muchas ocasiones esa ...

  14. L'anglais lingua franca de l'Union européenne : impératif de solidarité, source d'injustice, facteur de déclin ?

    OpenAIRE

    Van Parijs, Philippe

    2006-01-01

    La construction européenne peut-elle se justifier comme un instrument efficace au service de la solidarité ? Seulement si la démocratie européenne parvient à s'épaissir. Et pour s'épaissir, celle-ci doit impérativement adopter une lingua franca unique qui se superpose, sans se substituer, aux langues nationales et régionales existantes. Mais l'adoption comme lingua franca d'une des langues de l'Union ne créet-elle pas à son tour des injustices ? Si oui, comment y remédier ? Et la diffusion mê...

  15. Voyage au pays des Lau (îles Salomon, début du xxie siècle). Le déclin d’une gynécocratie, de Pierre Maranda

    OpenAIRE

    MAYER, Raymond

    2009-01-01

    Il est probablement tabou de référer trop ouvertement un ouvrage à un autre, mais il est évident que Tristes tropiques a fait des émules et qu’un long compagnonnage intellectuel avec Lévi-Strauss a fait forcément école, même si c’est partiellement sur des conclusions opposées. Le récit de Pierre Maranda ne commence pas par la formule « je hais les voyages », mais au contraire invite explicitement au voyage, en fournissant notamment, sous la forme de « conseils pratiques » (pp. 173-175), un sé...

  16. Is 13-Valent Pneumococcal Conjugate Vaccine (PCV13) Combined With 23-Valent Pneumococcal Polysaccharide Vaccine (PPSV23) Superior to PPSV23 Alone for Reducing Incidence or Severity of Pneumonia in Older Adults? A Clin-IQ

    Science.gov (United States)

    Hayward, Starla; Thompson, Lou Ann; McEachern, Andrea

    2016-01-01

    Pneumonia infection is a significant cause of morbidity and mortality worldwide. In addition to the public health concerns, pneumonia also accounts for a significant cost to the health care system. Currently there are two leading vaccines targeted against S. pneumoniae: 23-valent pneumococcal polysaccharide vaccine (PPSV23) and 13-valent pneumococcal conjugate vaccine (PCV13). Until recently the recommendation for adult pneumonia vaccination has been a single dose of PPSV23 for all adults 65 years and older. However, concerns were raised regarding the vaccine’s efficacy due to the persistent burden of pneumococcal disease in the elderly population. This paper focuses on two trials which evaluate the safety and efficacy of PCV13 in the adult population. The first study reveals improved immune response with the addition of PCV13 to PPSV23, while the second shows PCV13 was effective in the prevention of vaccine-type community-acquired pneumonia. The two studies observed adequate safety profiles for PCV13 in series with PPSV23 and with PCV13 compared to placebo. PMID:27376105

  17. Correction: Grömminger, S., et al. Fetal Aneuploidy Detection by Cell-Free DNA Sequencing for Multiple Pregnancies and Quality Issues with Vanishing Twins. J. Clin. Med. 2014, 3, 679-692

    Directory of Open Access Journals (Sweden)

    Sebastian Grömminger

    2014-11-01

    Full Text Available The authors wish to make the following corrections to this paper [1]: On page 683 at the end of Section 3.2. lines 13–14, the word “no” is missing. The correct sentence should be: “There has been no evidence of false-negative NIPT results so far in the pregnancies included in this study.”[...

  18. Is 13-Valent Pneumococcal Conjugate Vaccine (PCV13 Combined With 23-Valent Pneumococcal Polysaccharide Vaccine (PPSV23 Superior to PPSV23 Alone for Reducing Incidence or Severity of Pneumonia in Older Adults? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Starla Hayward

    2016-04-01

    Full Text Available Pneumonia infection is a significant cause of morbidity and mortality worldwide. In addition to the public health concerns, pneumonia also accounts for a significant cost to the health care system. Currently there are two leading vaccines targeted against Streptococcus pneumoniae: 23-valent pneumococcal polysaccharide vaccine (PPSV23 and 13-valent pneumococcal conjugate vaccine (PCV13. Until recently, the recommendation for adult pneumonia vaccination has been a single dose of PPSV23 for all adults aged 65 years or older. However, concerns were raised regarding the vaccine’s efficacy due to the persistent burden of pneumococcal disease in the elderly population. This paper focuses on two trials that evaluated the safety and efficacy of PCV13 in the adult population. The first study reveals improved immune response with the addition of PCV13 to PPSV23, while the second shows PCV13 was effective in the prevention of vaccine-type community-acquired pneumonia. Both studies observed adequate safety profiles for PCV13 in series with PPSV23 and with PCV13 compared to placebo.

  19. Le genre féerique illustré à l’époque victorienne : splendeurs et déclin d’un genre entré en résistance

    OpenAIRE

    Doussot, Audrey

    2015-01-01

    After having been blacklisted for decades, fairy tales unexpectedly came back into favour in Great Britain during the Victorian period, being staunchly supported by authors like Ruskin, Dickens or MacDonald. Visual arts too drew inspiration from fairy literature and lore, appropriating their themes, motifs and characters. In this context, illustrated Victorian fairy tales became vehicles of resistance against the banishment of imaginary supernatural literature and the rejection of illustratio...

  20. In Adult Smokers Unwilling or Unable to Quit, Does Changing From Tobacco Cigarettes to Electronic Cigarettes Decrease the Incidence of Negative Health Effects Associated With Smoking Tobacco? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Jennifer Brown

    2014-05-01

    Full Text Available Data from a randomized controlled trial and systematic review support the claim that switching from tobacco cigarettes to electronic cigarettes (e-cigarettes can reduce the short-term negative health effects of smoking. In adult smokers unwilling or unable to quit, exhaled carbon monoxide levels, total number of cigarettes smoked, and exposure to nitrosamine chemicals were reduced within a 12-month period. While the e-cigarette industry remains largely unregulated thus far, these studies provide encouraging hope in the uphill battle toward helping patients make informed and healthy choices.

  1. In adult smokers unwilling or unable to quit, does changing from tobacco cigarettes to electronic cigarettes decrease the incidence of negative health effects associated with smoking tobacco? A Clin-IQ

    Science.gov (United States)

    Brown, Jennifer; Brown, Brandon; Schwiebert, Peter; Ramakrisnan, Kalyanakrishnan; McCarthy, Laine H.

    2016-01-01

    Data from a randomized controlled trial and systematic review support the claim that switching from tobacco cigarettes to electronic cigarettes (e-cigarettes) can reduce the short-term negative health effects of smoking. In adult smokers unwilling or unable to quit, exhaled carbon monoxide levels, total number of cigarettes smoked, and exposure to nitrosamine chemicals were reduced within a 12-month period. While the electronic cigarette industry remains largely unregulated thus far, these studies provide encouraging hope in the uphill battle toward helping patients make informed and healthy choices. PMID:26855963

  2. Letters To The Editor: Rebuttal to Ottomanelli et al. Methods of a multisite randomized clinical trial of supported employment among veterans with spinal cord injury. J Rehabil Res Dev. 2009;46(7:919-30.

    Directory of Open Access Journals (Sweden)

    Marcel Dijkers, PhD

    2010-07-01

    Full Text Available Probably no fashion has gripped first medicine; then the rest of health care; and finally social services, vocational rehabilitation, education, and other professional fields as quickly and deeply as evidence-based practice (EBP. There have been claims that there is nothing new here, that professionals have always been required to base treatment of their patients/clients on evidence as to what are effective, efficient, and reliable methods of diagnosing/assessing, treating, or offering prognosis, and have done so. However, the core message of EBP has been a worthwhile one whatever one thinks of that claim: not any odd piece of evidence will do. To provide patients/clients with optimal service, one needs to base it on a systematic study of the most recent and most appropriate evidence, carefully evaluated for potential biases and errors. Probably as a result of the prominence of the originators of EBP in medicine, as well as the appealing and easy quantitative and mathematical approaches to evidence evaluation, EBP is now a bandwagon few people dare to disdain publicly. In fact, adding the label "evidence-based" to about anything and everything done professionally is seen as a way of giving it a modern, up-to-date, scientific cachet that will appeal to other professionals, if not patents/clients. EBP has become a holy cow to whom tribute is due.

  3. Rebuttal to McAleer J. Mobility redux: Post-World War II prosthetics and functional aids for veterans, 1945 to 2010. J Rehabil Res Dev. 2011;48(2:vii-xvi.

    Directory of Open Access Journals (Sweden)

    Stewart M. Coulter, PhD

    2011-07-01

    Full Text Available Dear Editor:This letter addresses the following sentence in the "Mobility redux: Post-World War II prosthetics and functional aids for veterans, 1945 to 2010" editorial that appeared in JRRD, Volume 48, Number 2. The sentence on page xv, second column: "Early testing and rigorous subject feedback clearly showed that DEKA II's first active socket design was not what patients wanted or needed." is not accurate. There is evidence in the historical literature on problematic prosthetic sockets. However, user response to the interface design introduced as part of the DEKA Arm System in collaboration with prosthetists at biodesigns, Inc (Santa Monica, California and Next Step Orthotics and Prosthetics, Inc (Manchester, New Hampshire has been quite favorable.It would be accurate to say "Early testing and rigorous subject feedback clearly showed that the active socket design used as part of the DEKA Arm System offers significant benefits and was positively received by research subjects."

  4. The development of [得 DE+V] and [V +得 DE]constructions in the Hunan dialects%湖南方言“得+V”和“V+得”结构的发展

    Institute of Scientific and Technical Information of China (English)

    伍云姬

    2001-01-01

    得DE"to obtain"is a linguistic sign which has a long history and has very complex usages.This paper will focus on the development of[DE+V]and[V+DE]constructions in which both the DE are Claimed to be used as modal auxiliaries and indicate the notion of possibilities in Chinese throughout the history.[DE+V]appeared earlier than[V+DE](Yue Junfa,1984,Yang Ping,1989,Sun Chaofen 1996,among others).Both constructions are rarely used in Mandarin but are till active in the Hunan dialects.The data in Hunan dialects show that[DE+V]and [V+DE]constructions do not only indicate possibilities,and even when the two constructions both indicate possibilities,they are not identical and not always interchangeable.In the Hunan dialects,the following contrasts between these two constructions can be found:[DE+V][V+DE] Volition Abiloty Possibility Permission Obligation Possibility In this paper,the different usages across localities in Hunan will examined, and the hypothesis of the order differences and the path of development will be stressed.This paper will concentrate on the [DE+V]and [V+DE]constructions.The focus will be on the semantic contrasts of these two constructions in which the word orders are opposite in the Hunan dialects,as well as the hypothesis of the paths of development of the two constructions.

  5. Matematické příběhy. Příběh devátý - Hádky řešte nim-em

    Czech Academy of Sciences Publication Activity Database

    Hejný, M.; Tichá, Marie

    2004-01-01

    Roč. 12, č. 3 (2004), s. 143-150. ISSN 1210-9037 R&D Projects: GA ČR GA406/02/0829 Institutional research plan: CEZ:AV0Z1019905 Keywords : teaching of mathematics * lower secondary lewel * game p theory Subject RIV: AM - Education

  6. Hassas radyal hız ölçümleriyle G-türü dev yıldızların çevresinde gezegen araştırmaları

    OpenAIRE

    Yilmaz, Mesut

    2011-01-01

       Bu tez çalışmasıyla, ülkemizde yeni bir araştırma alanı olarak, uluslararası bir işbirliği çerçevesinde TÜBİTAK Ulusal Gözlemevi’nde (TUG)  ilk kez Güneş Sistemi dışı  gezegen arama çalışmaları başlatıldı. Bu amaçla bazı dikine hız standardı yıldızların ve çevrelerinde gezegen barındırdığı bilinen bazı yıldızların yanı sıra bazı hedef yıldızların da I2 (iyodin) hücresi ile yüksek çözünürlüklü tayfları elde edildi. Gözlenen...

  7. Düşük ayağa yol açan, peroneal sinir komşuluğunda dev ekstranöral ganglion kisti olgusu

    OpenAIRE

    Aydinlar, Elif Ilgaz; TETİK, Cihangir; SILAV, Gökalp; KAYA, Behram; ÖZGEN, Serdar

    2015-01-01

    Extraneural ganglion cysts of the peroneal nerve have rarely been reported in the literature. This paper reports a large extraneural ganglion cyst compressing the peroneal nerve and causing pain in the leg, and foot drop. Electromyographic study revealed a deep peroneal nerve lesion, but the superficial branch was spared. Magnetic resonance imaging showed a cystic tumor located below the superior tibiofibular joint. A complete surgical resection was undertaken. During surgery multimodal intra...

  8. Rebuttal to McAleer J. Mobility redux: Post-World War II prosthetics and functional aids for veterans, 1945 to 2010. J Rehabil Res Dev. 2011;48(2):vii-xvi.

    OpenAIRE

    Stewart M. Coulter, PhD

    2011-01-01

    Dear Editor:This letter addresses the following sentence in the "Mobility redux: Post-World War II prosthetics and functional aids for veterans, 1945 to 2010" editorial that appeared in JRRD, Volume 48, Number 2. The sentence on page xv, second column: "Early testing and rigorous subject feedback clearly showed that DEKA II's first active socket design was not what patients wanted or needed." is not accurate. There is evidence in the historical literature on problematic prosthetic sockets. Ho...

  9. The application of low angle light scattering to evaluate qualitatively and quantitatively the dynamics of formation of oligomers in heme protein sensors

    Science.gov (United States)

    Sabino, Luis G.; Guimarães, Wellinson Gadelha; Costa, Pedro Mikael; Carepo, Marta S. P.; Gondim, Ana C. S.; Lopes, Luiz G. F.; Sousa, Eduardo H. S.

    2016-03-01

    The aim of this study is to investigate the structural organization and oligomerization properties of the sensory kinase protein DevS using low-angle light scattering (LALS) and gel filtration chromatography (HPLC). In addition, the structural characteristics of FixL and BSA were investigated and compared with DevS to better elucidate LALS technique. DevS is a direct and specific O2 sensing protein in Mycobacterium tuberculosis and acts as an activator of the transcription factor protein DevR. This latter triggers the latency state of tuberculosis under hypoxic conditions. DevS has been briefly evaluated under different conditions of concentration, ionic strength and temperature. LALS and gel filtration (HPLC) analysis were performed right after DevS purification process. The results of LALS for BSA proved to be highly reliable with a Rh value of c.a. 3.7 nm. Considering BSA a globular protein, the molecular weight estimative, using LALS was near 67 KDa, which is reasonably within the value reported in the literature. Preliminary LALS results showed a hydrodynamic radius (Rh) varying from 4.2-15.0 nm for DevS protein, and an average of 6.7 nm. These data supported, along with gel filtration, a dimer (~130 KDa) and tetramer (255 KDa) as the main DevS species. Additionally, it was found higher oligomeric species by gel filtration suggesting either an equilibrium of oligomers or an aggregation process that deserves further studies.

  10. Introduction : L’évolution des réseaux de chemins de fer d’intérêt local et des tramways voyageurs-marchandises de leur naissance à leur déclin, 1865-1951

    OpenAIRE

    Wolkowitsch, Maurice

    2015-01-01

    Ce colloque est consacré aux chemins de fer d’intérêt local et tramways voyageurs et marchandises définis par les lois de 1865, 1880 et 1913 ; ces réseaux partagent avec les lignes secondaires des grandes compagnies une même fonction de désenclavement des campagnes, mais ils méritent une étude spécifique. Ces réseaux secondaires dépassent 20 000 km en 1927, soit la moitié du réseau d’intérêt général ; ils emploient 26 000 cheminots, utilisent 1 500 locomotives et automotrices, 5 000 voitures,...

  11. L’essor et le déclin de la stratégie économique keynésienne – structuraliste au Mexique Rise and demise of the Structuralist-Keynesian economic strategy in Mexico La expansión y la declinación de la estrategia económica keynesiana-estructuralista en México

    Directory of Open Access Journals (Sweden)

    Julio López G.

    2012-04-01

    Full Text Available Pendant au moins deux décennies après la seconde guerre mondiale, la croissance économique au Mexique a été très rapide, à tel point que pour la caractériser, le terme « miracle mexicain » a été introduit. Le but de ce travail est d’étudier les causes immédiates ainsi que les origines historiques de l’essoufflement du miracle mexicain. L’auteur examine les limites de la stratégie fondée sur la substitution des importations en prenant en compte aussi bien des problèmes du côté de l’offre que de la demande. Il étudie aussi la relation entre économie et politique durant le « miracle », en mettant l’accent sur les accords et les conflits au sein des classes dominantes. Il montre comment les limites de l’offre et de la demande ont fait plus difficile de maintenir un taux de croissance élevé surtout après que le développement de l’économie mondiale s’est ralenti, à un moment où la substitution des importations avait atteint un niveau relativement avancé. Il avance l’hypothèse que le ralentissement de la croissance a aussi mis en danger l’accord implicite entre la haute bureaucratie d’état et les classes dominantes.The aim of this paper is to study the proximate causes as well as the historical origins of the downfall of the Mexican “economic miracle”, which took place approximately between 1950 and the mid-1970s. The author shares a view that holds that in the mid-1970s, Mexico’s previous growth strategy faded, and that sees the economic troubles as an expression of the exhaustion of that strategy. He shows how this economic exhaustion came about by considering the supply and demands limits to fast growth in an international context that deteriorated, especially when the import substitution strategy reached a relatively advanced stage. He then considers the relationship between economics and politics during the “miracle” period as much as in the following years, arguing that fast and stable growth also served as material support for an alliance between the upper classes and the political bureaucracy. Thus, the demise of the previous economic model also eroded the material and ideological framework that made possible or eased the class alliance built during the “miracle” years.Durante al menos dos décadas posteriores a la Segunda Guerra Mundial, el crecimiento de México fue muy rápido, hasta el punto de que para caracterizarlo se habló del « milagro mexicano ». El objetivo de este trabajo es el de estudiar las causas inmediatas así como los orígenes históricos del agotamiento del milagro mexicano. El autor examina los limites de la estrategia fundada en la sustitución de importaciones tomando en cuenta tanto los problemas del lado de la oferta como de la demanda. Estudia también la relación entre economía y política durante la vigencia del « milagro » poniendo el acento sobre los acuerdos y los conflictos en el seno de las clases dominantes. Muestra cómo los limites de la oferta y la demanda han hecho muy difícil mantener las tasas de crecimiento elevadas sobre todo después que se frenó el desarrollo de la economía mundial, en el momento en que la sustitución de importaciones había alcanzado un nivel relativamente elevado.

  12. L’essor et le déclin de la stratégie économique keynésienne – structuraliste au Mexique Rise and demise of the Structuralist-Keynesian economic strategy in Mexico La expansión y la declinación de la estrategia económica keynesiana-estructuralista en México

    OpenAIRE

    Julio López G.

    2012-01-01

    Pendant au moins deux décennies après la seconde guerre mondiale, la croissance économique au Mexique a été très rapide, à tel point que pour la caractériser, le terme « miracle mexicain » a été introduit. Le but de ce travail est d’étudier les causes immédiates ainsi que les origines historiques de l’essoufflement du miracle mexicain. L’auteur examine les limites de la stratégie fondée sur la substitution des importations en prenant en compte aussi bien des problèmes du côté de l’offre que d...

  13. Recombinant duck enteritis viruses expressing major structural proteins of the infectious bronchitis virus provide protection against infectious bronchitis in chickens.

    Science.gov (United States)

    Li, Huixin; Wang, Yulong; Han, Zongxi; Wang, Yu; Liang, Shulin; Jiang, Lu; Hu, Yonghao; Kong, Xiangang; Liu, Shengwang

    2016-06-01

    To design an alternative vaccine for control of infectious bronchitis in chickens, three recombinant duck enteritis viruses (rDEVs) expressing the N, S, or S1 protein of infectious bronchitis virus (IBV) were constructed using conventional homologous recombination methods, and were designated as rDEV-N, rDEV-S, and rDEV-S1, respectively. Chickens were divided into five vaccinated groups, which were each immunized with one of the rDEVs, covalent vaccination with rDEV-N & rDEV-S, or covalent vaccination with rDEV-N & rDEV-S1, and a control group. An antibody response against IBV was detectable and the ratio of CD4(+)/CD8(+) T-lymphocytes decreased at 7 days post-vaccination in each vaccinated group, suggesting that humoral and cellular responses were elicited in each group as early as 7 days post-immunization. After challenge with a homologous virulent IBV strain at 21 days post-immunization, vaccinated groups showed significant differences in the percentage of birds with clinical signs, as compared to the control group (p < 0.01), as the two covalent-vaccination groups and the rDEV-S group provided better protection than the rDEV-N- or rDEV-S1-vaccinated group. There was less viral shedding in the rDEV-N & rDEV-S- (2/10) and rDEV-N & rDEV-S1- (2/10) vaccinated groups than the other three vaccinated groups. Based on the clinical signs, viral shedding, and mortality rates, rDEV-N & rDEV-S1 covalent vaccination conferred better protection than use of any of the single rDEVs. PMID:26946113

  14. West Syndrome in South Iran: Electro-Clinical Manifestations

    Directory of Open Access Journals (Sweden)

    ALI Akabar ASADI-POOYA

    2013-08-01

    . Infantile spasms: West syndrome. Arch Neurol. 2002 Feb;59(2:317-8.3. Hrachovy RA. West’s syndrome (infantile spasms.Clinical description and diagnosis. Adv Exp Med Biol.2002;497:33-50. Review.4. Riikonen R, Donner M. Incidence and aetiology of infantile spasms from 1960 to 1976: a population study in Finland. Dev Med Child Neurol. 1979 Jun;21(3:333-43.5. Dulac O. What is West syndrome? Brain Dev. 2001 Nov;23(7:447-52. Review. 6. Wong V. West syndrome-The University of Hong Kong experience (1970-2000. Brain Dev. 2001 Nov;23(7:609-15.7. Kalra V, Gulati S, Pandey RM, Menon S. West syndrome and other infantile epileptic encephalopathies -Indian hospital experience. Brain Dev. 2001 Nov; 23(7:593-602. Corrected and republished in: Brain Dev. 2002 Mar;24(2:130-9.8. Young C; Taiwan Child Neurology Society. National survey of West syndrome in Taiwan. Brain Dev. 2001 Nov;23(7:570-4.9. Asadi-Pooya AA, Mintzer S, Sperling MR. Nutritional supplements, foods, and epilepsy: is there a relationship?Epilepsia. 2008 Nov;49(11:1819-27.10. Mikati MA, Trevathan E, Krishnamoorthy KS, Lombroso CT. Pyridoxine - dependent epilepsy: EEG investigations and long-term follow-up. Electroencephalogr Clin Neurophysiol. 1991 Mar;78(3:215-21.11. Nabbout R, Soufflet C, Plouin P, Dulac O. Pyridoxine dependent epilepsy: a suggestive electroclinical pattern. Arch Dis Child Fetal Neonatal Ed. 1999 Sep;81(2:F125-9.12. Gospe SM Jr. Pyridoxine-dependent seizures: new genetic and biochemical clues to help with diagnosis and treatment. Curr Opin Neurol. 2006 Apr;19(2:148-53. Review.13.Riikonen R. The latest on infantile spasms. Curr Opin Neurol. 2005 Apr;18(2:91-5. Review.

  15. Asociaciones palinológicas en las formaciones Los Monos (Devónico) e Itacua (Carbonífero Inferior) en Balapuca (Cuenca Tarija), sur de Bolivia: Parte 1. Formación Los Monos Palynological assemblages present in Los Monos (Devonian) and Itacua (Lower Carboniferous) formations at Balapuca (Tarija basin), southern Bolivia: Part One. Los Monos Formation

    OpenAIRE

    Mercedes di Pasquo

    2007-01-01

    Se caracterizan cuali-cuantitativamente dos asociaciones palinológicas recuperadas de ocho muestras fértiles de la Formación Los Monos (Eifeliano tardío-Frasniano temprano), expuesta en la localidad de Balapuca, ubicada en la margen boliviana del río Bermejo en la sierra de San Telmo. Esta unidad depositada en la Cuenca Tarija, sobreyace a la Formación Pescado (o Huamampampa, Emsiano-Eifeliano), y subyace, cuando está preservada, a la Formación Iquirí (Frasniano-Famenniano). La sección litoló...

  16. Neuroimaging in Cerebral Palsy – Report from North India

    Directory of Open Access Journals (Sweden)

    Anju AGGARWAL

    2013-11-01

    ;109:8-14.http://www.newbornwhocc.org/pdf/database.pdfRikomen R, Raumanvrita S, Sinivuori E, Seppala T. Changing pattern of cerebral palsy in southwest region of Finland. Acta Pediatr Scand 1989; 78(4:581-7.Pharaoh POD, Plat MJ, Cooke T. The changing epidemiology of cerebral palsy. Arch Dis Child 1996;75(3: F169-73.Eischer PS, Batshaw M. Cerebral Palsy. Ped Clin North Am 1993;40(3:537-51.Bax M, Tydeman BA, Flodmark O. Clininical and MRI correlates of cerebral palsy: the European Cerebral PalsyStudy. JAMA 2006; 296(13:1602-08.Korzeniewski SJ, Birbeck G, DeLano MC, Potchen MJ, Paneth N. A systematic review of neuroimaging for cerebral palsy. Journal of Child Neurology 2008;23(2:216-27.Robinson MN, Peake LJ, Ditchfield MR, Reid SM. Magnetic Resonance imaging findings in population based cohort of children with cerebral palsy Dev Med Child Neurol 2009; 51(1:39-45.Shevell M, Ashwal S, Donley D, Flint J, Gingold M, Hirtz D, et al. Practice parameter: Evaluation of the child with global developmental delay: Report of the Quality Standards Subcommittee of the American Academy of Neurology and The Practice Committee of the Child Neurology Society. Neurology 2003; 60(3; 367-80.Ashwal S, Russman BS, Blasco PA, Miller G, Sandler A, Shevell M, et al. Practice parameter: diagnostic assessment of the child with cerebralpalsy: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology 2004; 23;62(6: 851-63. 

  17. Associations between Manual Abilities, Gross Motor Function, Epilepsy, and Mental Capacity in Children with Cerebral Palsy

    Directory of Open Access Journals (Sweden)

    Ewa GAJEWSKA*

    2014-04-01

    2013;111:183-95.Sellier E, Uldall P, Calado E, Sigurdardottir S, Torrioli MG, Platt MJ, et al. Epilepsy and cerebral palsy: characteristics and trends in children born in 1976-1998. Eur J Paediatr Neurol 2012;16(1:48-55.Wallace SJ. Epilepsy in cerebral palsy. Dev Med Child Neurology 2001;43(10:713-7.Bax MCO. Cerebral palsy. In: Aicardi J, editor. Disease of the nervous system in childhood. 2nd ed. London: Mc Keith Press; 1998. p. 210-39.Reid A, Imrie H, Brouwer E, Clutton S, Evans J, Russell D, et al. “If I knew then what I know now”: parents’ reflections on raising a child with cerebral palsy. Phys Occup Ther Pediatr 2011;31(2:169-83.Rosenbaum P, Paneth N, Leviton A, Goldstein M, Bax M, Damiano D, et al. A report: the definition and classification of cerebral palsy April 2006. Dev Med Child Neurology 2007;109:8-14.Palisano R, Rosenbaum P, Bartlett D, Livingston M. Content validity of the expanded and revised Gross Motor Function Classification System. Dev Med Child Neurology 2008;50(10:744-50.Öhrvall AM, Eliasson AC. Parents and therapists perceptions about the content and construct of Manual Ability Classification System, MACS. Scand J Occup Ther 2010;17(3:209-16.Marszał E.Występowanie, diagnostyka i leczenie padaczki u dzieci z mózgowym porażeniem dziecięcym. Neurologia dziecięca;2006:15, 30:65-8.Blair E, Watson L. Epidemiology of cerebral palsy. Semin Fetal Neonatal Medicine 2006;11(2:117-25.Meberg A, Broch H. Etiology of cerebral palsy. J Perinat Med 2004;32(5:434-9.Blair E. Epidemiology of the cerebral palsies. Orthop Clin North Am 2010;41(4:441-55.Hellbrűge T, Fritz L, Menara D, Schamberger R, Rautenstrauch T. Monachijska Funkcjonalna Diagnostyka Rozwojowa. Kraków: Antykwa; 1994. p. 80-130.Arnould C, Penta M, Renders A, Thonnard JL. Abilhand-Kids: a measure of manual ability in children with cerebral palsy. Neurology 2004;63(6:1045-52.Carnahan KD, Arner M, Hägglund G. Association between gross motor function (GMFCS and manual ability (MACS in

  18. Disease: H01006 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available oaches in hereditary angioedema. Clin Rev Allergy Immuno...vis AE 3rd The pathophysiology of hereditary angioedema. Clin Immunol 114:3-9 (2005) PMID:21279474 (drug) Antoniu SA Therapeutic appr

  19. A "Research" into International Student-Related Research: (Re)visualising Our Stand?

    Science.gov (United States)

    Abdullah, Doria; Abd Aziz, Mohd Ismail; Mohd Ibrahim, Abdul Latiff

    2014-01-01

    This paper uses Tight ("High Educ Res Dev" 23(4):395-411, 2004; "High Educ Res Dev" 31(5):723-740, 2012; "High Educ Res Dev" 32(1):136-151, 2013)'s journal analysis and review framework to review a sample of 497 journal articles on researches concerning international students over the past 30 years. It was found…

  20. Strategy for increasing marine fish production in Goa

    Digital Repository Service at National Institute of Oceanography (India)

    Parulekar, A.H.

    stream_size 5 stream_content_type text/plain stream_name Proc_Workshop_Evol_Strat_Dev_Agric_Anim_Husb_Fish_Goa_1991_73.pdf.txt stream_source_info Proc_Workshop_Evol_Strat_Dev_Agric_Anim_Husb_Fish_Goa_1991_73.pdf.txt Content...

  1. Estimation of wave forces on a tethered spherical float using potential flow theory

    Digital Repository Service at National Institute of Oceanography (India)

    Vethamony, P.; Chandramohan, P.; Sastry, J.S.

    stream_size 9 stream_content_type text/plain stream_name Proc_Int_Conf_Coast_Port_Eng_Dev_Countries_1991_1442.pdf.txt stream_source_info Proc_Int_Conf_Coast_Port_Eng_Dev_Countries_1991_1442.pdf.txt Content-Encoding ISO-8859...

  2. Application of acoustic techniques for exploration of submerged area in connection with hydro-projects

    Digital Repository Service at National Institute of Oceanography (India)

    Vora, K.H.

    stream_size 7 stream_content_type text/plain stream_name Indian_J_Power_River_Valley_Dev_43_163.pdf.txt stream_source_info Indian_J_Power_River_Valley_Dev_43_163.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset...

  3. Brief Report: Insistence on Sameness, Anxiety, and Social Motivation in Children with Autism Spectrum Disorder

    Science.gov (United States)

    Factor, Reina S.; Condy, Emma E.; Farley, Julee P.; Scarpa, Angela

    2016-01-01

    While the function of restricted repetitive behaviors (RRBs) in autism spectrum disorder (ASD) is unclear, RRBs may function as anxiety reduction strategies (Joosten et al. "J Autism Dev Disord" 39(3):521-531, 2009. Moreover, anxiety in ASD is associated with low social motivation (Swain et al. "J Autism Dev Disord," 2015. The…

  4. 40 CFR Table F-3 to Subpart F of... - Critical Parameters of Idealized Ambient Particle Size Distributions

    Science.gov (United States)

    2010-07-01

    ... Ambient Particle Size Distributions F Table F-3 to Subpart F of Part 53 Protection of Environment... Ambient Particle Size Distributions Idealized Distribution Fine Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) Coarse Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) PM2.5/PM10 Ratio FRM...

  5. Disease: H00106 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee. J Allergy Clin Immunol 120:776-94 (2007) ...

  6. Disease: H00101 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee. J Allergy Clin Immunol 120:776-94 (2007) ...

  7. The Best Time for EEG Recording in Febrile Seizure

    Directory of Open Access Journals (Sweden)

    Parvaneh KARIMZADEH

    2014-01-01

    seizures. Arch Pediatr Adolesc Med 1997;151(4:371-8.Nelson KB, Ellenberg JH. Predictors of epilepsy in children who have experienced febrile seizures. N Engl J Med 1976;295(19:1029-33.Anonymous. Practice parameter: the neurodiagnostic evaluation of the child with a first simple febrile seizure. American Academy of Pediatrics. Provisional Committee on Quality Improvement, Subcommittee on Febrile Seizures. Pediatrics 1996;97(5:769-72; discussion:773-5.Rosman NP. Evaluation of the child who convulses with fever. Paediatr Drugs 2003;5(7:457-61.Kanemura H, Mizorogi S, Aoyagi K, Sugita K, Aihara M. EEG characteristics predict subsequent epilepsy in children with febrile seizure. Brain Dev 2012;34(4:302-7.Yamatogi Y, Ohtahara S. EEG in febrile convulsions. Am J EEG Techno1 1990;30:267-80.Aicardi J, Chevrie JJ. The significance of electroencephalographic paroxysms in children less than 3 years of age. Epilepsia 1973;14(1:47-55.Tsuboi T. Seizures of childhood: a population-based and clinic based study. Acta Neurol Scand Suppl 1986;110:1-237.Maytal J, Steele R, Eviatar L, Novak G. The value of early postictal EEG in children with complex febrile seizures. Epilepsia 2000;41(2:219-21.Joshi C, Wawrykow T, Patrick J, Prasad A. Do clinical variables predict an abnormal EEG in patients with complex febrile seizures? Seizure 2005;14(6:429-34.Lennox-Buchthal M. Febrile convulsions: a reappraisal. Electroencephalogr Clin Neurophysiol 1973;32:Suppl:1-138.Frantzen E, Lennox-Buchtal MA, Nygraad A. Longitudinal EEG and clinical study of children with febrile convulsions. Electroencephalogr Clin Neurophysiol 1968;24(3:197-212.Kajitani T, Ueoka K, Nakamura M, Kumanomidou Y. Febrile convulsions and rolandic discharges. Brain Dev 1981;3(4:351-9.Sofijanov N, Emoto S, Kuturec M, Dukovski M, Duma F, Ellenberg JH, et al. Febrile seizures: clinical characteristics and initial EEG. Epilepsia 1992;33(1:52-7.

  8. Disease: H01068 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available d by Haemophilus aphrophilus: case report and review. Clin Microbiol Infect 7:107-13 (2001) PMID:8170429 (de...o A, Miro JM, Coca A Haemophilus paraphrophilus endocarditis: case report and review. Clin Infect Dis 20:1381-3 (1995) ...

  9. Use of CD40L immunoconjugates to overcome the defective immune response to vaccines for infections and cancer in the aged.

    Science.gov (United States)

    Tang, Yu Cheng; Thoman, Marilyn; Linton, Phyllis-Jean; Deisseroth, Albert

    2009-12-01

    Multiple investigators have reported the presence of defects in the immune response of the elderly [Castle In: Clin Infect Dis 31:578, 2000; Ortqvist et al. In: Eur Respir J 30:414-422, 2007; Saurwein-Teissl et al. In: J Immunol 168:5893, 2002; Haynes et al. In: Proc Natl Acad Sci USA 100:15053-15058, 2003]. These defects reduce the magnitude of the immune response to infection and to vaccination. In individuals greater than 55 years of age, the probability of developing a fully protective neutralizing antibody response to the yearly multivalent particle inactivated influenza vaccine is less than 20% [Jefferson et al. In: Lancet 264:1165-1174, 2005; Goodwin et al. In: Vaccine 24:1159-1169, 2006; Jackson et al. In: Lancet 372:398-405, 2008; Simonsen and Taylor In: Lancet 7:658-666, 2007]. The defects in the aged immune system that are responsible for this limited response to vaccination in the older age groups include functional defects of the antigen presenting cells, functional defects in CD4 helper CD4 T cells and monocytes, and an altered microenvironment [Eaton et al. In: J Exp Med 200:1613-1622, 2004; Dong et al. In: J Gen Virol 84:1623-1628, 2003; Deng et al. In: Immunology 172:3437-3446, 2004; Cella et al. In: J Exp Med 184:747-752, 1996]. Starting at puberty, the involution of the thymus and the consequent reduction of the export of naïve T cells specific to neo-antigens leads to the reduction of the ratio of antigen naïve to memory cells as chronological age advances [Prelog In: Autoimmun Rev 5:136-139, 2006; McElhaney et al. In: J Immunology 176:6333-6339, 2006]. Changes in glycosylation of T cells and target antigens acquired during the aging process and the antibodies to these new glycopeptides and glycoproteins may also contribute to a reduction in the functioning of the adaptive immune response [Ishii et al. In: J Clin Neurosci 14:110-115, 2007; Shirai et al. In: Clin Exp Immunol 12:455-464, 1972; Adkins and Riley In: Mech Ageing Dev 103

  10. Characterization of duck enteritis virus UL53 gene and glycoprotein K

    OpenAIRE

    Yang Xiaoyuan; Wu Ying; Wang Mingshu; Cheng Anchun; Xiang Jun; Zhang Shunchuan; Zhu Dekang; Jia Renyong; Luo Qihui; Chen Zhengli; Chen Xiaoyue

    2011-01-01

    Abstract Background Most of the previous research work had focused on the epidemiology and prevention of duck enteritis virus (DEV). Whilst with the development of protocols in molecular biology, nowadays more and more information about the genes of DEV was reported. But little information about DEV UL53 gene and glycoprotein K(gK) was known except our reported data. Results In our paper, the fluorescent quantitative real-time PCR(FQ-RT-PCR) assay and nucleic acid inhibition test were used to...

  11. A Comparison of Risperidone and Buspirone for Treatment of Behavior Disorders in Children with Phenylketonuria

    Directory of Open Access Journals (Sweden)

    Afshin FAYYAZI

    2014-12-01

    and Lang W .Neurobehavioral Problems Associated with Phenylketonuria. Psychiatry (Edgemont 2009; 7(12:29–32.Luciana M, Hanson K L,Whitley C B.A preliminary report on dopamine system reactivity in PKU: acute effects of haloperidol on neuropsychological, physiological, and neuroendocrine functions. Psychopharmacology 2004;175: 18–25.Pappadopulos E, Woolston S, Chait A, Perkins M, Connor DF, Jensen P S. Pharmacotherapy of Aggression in Children and Adolescents: Efficacy and Effect Size. J CDN ACAD Child Adolesc Psychiatry 2006; 15(1:27-39.Shea S, Turgay A, Carroll A, Schulz M, Orlik H ,Smith I and et al. Risperidone in the Treatment of Disruptive Behavioral Symptoms in Children With Autistic and Other Pervasive Developmental Disorders. Pediatrcs 2004; 114:634-641.Miral S, Gencer O, Inal-Emiroglu F.N, Baykara B, Baykara A, Dirik E. Risperidone versus haloperidol in children and adolescents with AD: a randomized, controlled, doubleblind trial. Eur Child Adolesc Psychiatry 2008; 17:1–8.Aman M.G, Hollway J.A, McDougle C.J, Scahill L, Tierney E, McCracken J.T and et al. Cognitive effects of risperidone in children with autism and irritable behavior. J. Child Adolesc. Psychopharmacol 2008; 18:227–236.Pandina G.J, Bossie C.A, Youssef E, Zhu Y, Dunbar F. Risperidone improves behavioral symptoms in children with autism in a randomized, double-blind, placebocontrolled trial. J Autism Dev Disord 2007; 37:367–373.Luby J, Mrakotsky C, Stalets M.M, Belden A, Heffelfinger A, Williams M and et al. Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy. J. Child Adolesc. Psychopharmacol 2006; 16:575–587.Nagaraj R, Singhi P, Malhi P. Risperidone in children with autism: randomized, placebo controlled, double blind study. J. Child Neurol 2006; 21:450–455.Haas M, Karcher K, Pandina GJ. Treating Disruptive Behavior Disorders with Risperidone: A 1-Year, Open-Label Safety Study in Children and Adolescents. Journal of Child and

  12. Disease: H00368 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ctivated. CMV is an important and common cause of mortality and morbidity in immunocompromised patients...on in non-immunosuppressed critically ill patients. J Infect Dev Ctries 5:571-9 (2011) ...

  13. Disease: H01090 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01090 Ascariasis Ascariasis is an commonly documented parasitic infection in sub-Saharan Africa ... ID:6377443 (description) Arfaa F Selective primary health ... care: strategies for control of disease in the dev ...

  14. The Land Administration Domain Model

    NARCIS (Netherlands)

    Lemmen, C.; Van Oosterom, P.J.M.; Bennett, R.

    2015-01-01

    Societal drivers including poverty eradication, gender equality, indigenous recognition, adequate housing, sustainable agriculture, food security, climate change response, and good governance, influence contemporary land administration design. Equally, the opportunities provided by technological dev

  15. Disease: H00021 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available mas. Curr Opin Genet Dev 19:82-91 (2009) PMID:9498904 (carcinogen) Boffetta P, Jourenkova N, Gustavsson P. Cancer risk from occupatio...nal and environmental exposure to polycyclic aromatic hydrocarbons. Cancer Causes C

  16. Comment on Schularick: Real Sector Globalization Precedes Financial Globalization

    OpenAIRE

    Kar Dev

    2010-01-01

    Financial globalization cannot evolve in a vacuum. Dev Kar argues that real globalization in product markets is the ultimate source of financial globalization and must enter the equation when considering remedies.

  17. Monitor

    Data.gov (United States)

    US Agency for International Development — A custom-built, dual-language (English and Spanish) system (http://www.monitor.net.co/) developed by DevTech that debuted in January 2011. It features a central PMP...

  18. Genetics Home Reference: familial glucocorticoid deficiency

    Science.gov (United States)

    ... Clark AJ, Metherell LA. ACTH resistance: genes and mechanisms. Endocr Dev. 2013;24:57-66. doi: 10. ... Metherell LA. Familial glucocorticoid deficiency: New genes and mechanisms. Mol Cell Endocrinol. 2013 May 22;371(1- ...

  19. Letters to the Editor

    OpenAIRE

    Brian C. Lund, PharmD, MS; Thad E. Abrams, MD, MS

    2011-01-01

    Rebuttal to Gravely et al. Validity of PTSD diagnoses in VA administrative data: Comparison of VA administrative PTSD diagnoses to self-reported PTSD Checklist scores. J Rehabil Res Dev. 2011; 48(1):21–30.

  20. Annular Hybrid Rocket Motor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Engineers at SpaceDev have conducted a preliminary design and analysis of a proprietary annular design concept for a hybrid motor. A U.S. Patent application has...

  1. EVALUATION OF THE CARBON FOOTPRINT OF INNOVATIVE WATER MAIN REHABILITATION TECHNOLOGIES VS. OPEN CUT METHODS

    Science.gov (United States)

    A major benefit of trenchless rehabilitation technologies touted by many practitioners when comparing their products with tradition open cut construction methods is lower carbon dioxide (CO2) emissions. In an attempt to verify these claims, multiple tools have been dev...

  2. 76 FR 13191 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

    Science.gov (United States)

    2011-03-10

    ... Peachtree Street, NE., Atlanta, Georgia 30309: 1. Teche Holding Company, New Iberia, Louisiana; to become a... Iberia, Louisiana. Board of Governors of the Federal Reserve System, March 7, 2011. Robert deV....

  3. Dosimetry study on A p-n junction semiconductor detector

    International Nuclear Information System (INIS)

    A p-n junction semiconductor may be used as a radiation detector. Such a study is reported here. Its dosimetry specificities, include dose, dose rate, precision, stability, depth dose distribution and directional response, were studied in a 60Co field. It is shown that the detector performs well. It exhibited a precision of ±0.05% (std dev.) and a stability of ±0.16% (std dev.), respectively. (author)

  4. SimStudio : une Infrastructure pour la Modélisation, la Simulation et l'Analyse de Systèmes Dynamiques Complexes

    OpenAIRE

    Touraille, Luc; Kaba Traoré, Mamadou; Hill, David

    2010-01-01

    SimStudio is a Modeling & Simulation framework based on the DEVS formalism (Discrete EVent Systems Specification). SimStudio architecture aims at integrating in a single platform tools for modeling, simulation, analysis and collaboration, by proposing model transformation features (code generation, among others) in order to smooth the modeling and simulation cycle. To achieve this, SimStudio is built upon the DEVS formalism, recognize by many as a "universal" simulation formalism, and upon a ...

  5. Activity in PythonPDEVS

    OpenAIRE

    Van Tendeloo Yentl; Vangheluwe Hans

    2014-01-01

    We introduce an activity-enhanced version of PythonPDEVS, a Parallel DEVS simulator. PythonPDEVS supports both sequential and distributed simulation. Both sequential and distributed variants of PythonPDEVS exploit information about computational activity to reduce simulation time. DEVS models can be augmented by the user with domain-specific information about computational load. This information is used by the simulator to improve performance.

  6. Evaluation of immune functions of rainbow trout (Oncorhynchus mykiss) how can environmental influences be detected?

    OpenAIRE

    Köllner, Bernd; Wasserrab, Birgit; Kotterba, Günter; Fischer, Uwe

    2002-01-01

    In fish, the first line of defense against infectious microorganisms is based on a broad range of nonspecific humoral and cellular immune mechanisms ( innate immunity ) which without prior specific activation can act in forming a more static barrier (Fish Shellfish Immunol. 10 (2000) 243; Dev. Comp. Immunol. 25 (2001) 827). This natural resistance is normally effective enough to protect fish from infectious diseases until specific immune responses are being induced (Fig. 1; Dev. Comp. Immunol...

  7. Characterization of duck enteritis virus UL53 gene and glycoprotein K

    Directory of Open Access Journals (Sweden)

    Yang Xiaoyuan

    2011-05-01

    Full Text Available Abstract Background Most of the previous research work had focused on the epidemiology and prevention of duck enteritis virus (DEV. Whilst with the development of protocols in molecular biology, nowadays more and more information about the genes of DEV was reported. But little information about DEV UL53 gene and glycoprotein K(gK was known except our reported data. Results In our paper, the fluorescent quantitative real-time PCR(FQ-RT-PCR assay and nucleic acid inhibition test were used to study the transcription characteristic of the DEV UL53 gene. Except detecting the mRNA of DEV UL53 gene, the product gK encoded by UL53 gene was detected through the expression kinetics of UL53 gene by the purified rabbit anti-UL53 protein polyclonal antibodies. Western-blotting and indirect immunofluorescence assays were used to detect gK. From the results of these experiments, the UL53 gene and gK were respectively identified as a late gene and a really late protein. On the other hand, the indirect immunofluorescence assay provided another information that the intracellular localization of DEV gK was mainly distributed in cytoplasm. Conclusions By way of conclusions, we conceded that DEV UL53 gene is a really late gene, which is coincident with properties of UL53 homologs from other herpesvirus, such as ILTV(Infectious Laryngotracheitis virus and HSV-1(Herpes simplex virus type 1. The properties of intracellular localization about gK protein provided a foundation for further functional analysis and further studies will be focused on constructing of the UL53 gene DEV mutant.

  8. Characterization of codon usage bias in the dUTPase gene of duck enteritis virus

    Institute of Scientific and Technical Information of China (English)

    Lichan Zhao; Anchun Cheng; Mingshu Wang; Guiping Yuan; Mingsheng Cai

    2008-01-01

    A comparative analysis of the codon usage bias in the newly discovered dUTPase gene(Assigned Accession No.:DQ4861491 of the duck enteritis virus(DEV)and the dUTPase gene of 32 reference herpesviruses was performed.The results indicated that the DEV dUT-Pase gene encodes a protein of 477 amino acids,which includes five conserved motifs with a 3-1-2-4-5 arrangement.The codon adap-tation index(CAI),effective number of codons(ENC),and GC3s values indicated synonymous codon usage bias in the dUTPase gene of herpesviruses,and this synonymous bias was correlated with host evolution.The codon usage pattens of the DEV dUTPase gene were phylogenetically conserved and similar to that of the dUTPase genes of the avian alphaherpesvirus.Although codon usage in each micro-orgamsm was different,there were no strain-specific differences among them.Sixty-one codons in the predicted polypeptide.with a strong bias towards A and T at the third codon position,were used.Comparison of the codon usage in the dUTPase gene of different organisms revealed that there were 19 codons showing distinct codon usage differences between the DEV and Escherichia coli dUTPase genes;16 between the DEV and yeast dUTPase genes;and 15 between the DEV and human dUTPase genes.Analysis of variance(ANOVA) showed significant differences between the DEV and yeast dUTPase genes(r=0.536,P<0.01).The extent of codon usage bias in the DEV dUTPase gene was highly correlated with the gene expression level,therefore the results may provide usefu information for gene classification and functional studies.

  9. In silico discovery of the dormancy regulons in a number of Actinobacteria genomes

    Energy Technology Data Exchange (ETDEWEB)

    Gerasimova, Anna; Dubchak, Inna; Arkin, Adam; Gelfand, Mikhail

    2010-11-16

    Mycobacterium tuberculosis is a dangerous Actinobacteria infecting nearly one third of the human population. It becomes dormant and phenotypically drug resistant in response to stresses. An important feature of the M. tuberculosis pathogenesis is the prevalence of latent infection without disease, making understanding of the mechanisms used by the bacteria to exist in this state and to switch to metabolically active infectious form a vital problem to consider. M. tuberculosis dormancy is regulated by the three-component regulatory system of two kinases (DosT and DevS) and transcriprional regulator (DevR). DevR activates transcription of a set of genes, which allow the bacteria to survive long periods of anaerobiosis, and may be important for long-term survival within the host during latent infection. The DevR-regulon is studied experimentally in M. tuberculosis and few other phylogenetically close Mycobacteria spp. As many other two-component systems, the devRS operon is autoregulated. However, the mechanism of the dormancy is not completely clear even for these bacteria and there is no data describing the dormancy regulons in other species.

  10. Downhill oesophageal varices resulting from superior vena cava graft occlusion after resection of a thymoma†

    Science.gov (United States)

    Inoue, Yoshimasa; Sakai, Shoji; Aoki, Teruhiro

    2013-01-01

    Downhill oesophageal varices (DEV) may occur as a rare complication of superior vena cava (SVC) obstruction. DEV are usually associated with SVC obstruction caused by systemic vasculitis or mediastinal tumours. In this report, we describe a very rare case of DEV resulting from SVC graft occlusion after resection of a thymoma. A 66-year old man with an invasive thymoma was treated by radical resection and bypass grafting from the right brachiocephalic vein to the right atrium. Occlusion of the SVC graft was diagnosed postoperatively; however, the patient could be managed conservatively. Although there had been no significant findings in the oesophagus in previous endoscopic examinations, grade F2 varices were found in the proximal oesophagus in the 19th postoperative month, and DEV caused by SVC graft occlusion was diagnosed. Until now, 2 years since the diagnosis, no apparent symptoms or deterioration of the DEV have been observed. The possible development of DEV should be borne in mind during the follow-up of patients with postoperative SVC graft occlusion. PMID:23686892

  11. Effets des éléments boisés sur les populations d'abeilles sauvages dans un paysage agricole, cas du verger de pommes dans le Cher

    OpenAIRE

    Lagarde, N

    2011-01-01

    / Les abeilles et les bourdons (Hyménoptères Apoïdes) sont en déclin depuis une trentaine d'années. Ce déclin résulte probablement de l'action simultanée et synergique d’un ensemble de facteurs, d’ampleurs unitaires faibles. Parmi eux, la dégradation et fragmentation des habitats serait le facteur principal du déclin des abeilles sauvages. Les lisières forestières proposent de nombreux sites de nidifications et des ressources alimentaires diversifiées et durables, et seraient susc...

  12. Autism Spectrum Disorders in Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Reza MOHAMMADI

    2011-12-01

    2007; 28: 235-258.Zaroff CM, Uhm SY. Prevalence of autism spectrum disorders and influence of country of measurement and ethnicity. Soc Psychiatry Psychiatr Epidemiol 2011;published online.Baron-Cohen S, Scott FJ, Allison C, Williams J, Bolton P, Matthews FE, et al. Prevalence of autism-spectrum conditions: UK school-based population study. Br J Psychiatry 2009;194:500-509.Brugha TS, McManus S, Bankart J, Scott F, Purdon S, SmithJ, et al. Epidemiology of autism spectrum disorders inadults in the community in England. Arch Gen Psychiatry 2011; 68: 459-465.Prevalence of autism spectrum disorders - Autism and Developmental Disabilities Monitoring Network, United States, 2006. MMWR Surveill Summ 2009; 58: 1-20.Fombonne E. Epidemiology of pervasive developmental disorders. Pediatr Res 2009; 65: 591-598.Ehlers S, Gillberg C. The epidemiology of Asperger syndrome. A total population study. J Child Psychol Psychiatry 1993; 34: 1327-1350.Kadesjo B, Gillberg C, Hagberg B. Brief report: autismand Asperger syndrome in seven-year-old children: a totalpopulation study. J Autism Dev Disord 1999; 29: 327-331.Williams JG, Higgins JP, Brayne CE. Systematic reviewof prevalence studies of autism spectrum disorders. ArchDis Child 2006; 91: 8-15.Bernier R, Mao A, Yen J. Psychopathology, families, andculture: autism. Child Adolesc Psychiatr Clin N Am 2010;19: 855-867.Shamsi-pour M, Yonesian M, Mansouri A. Epidemiologyof autism: recent challenges in prevalence of autism andits risk factors. Journal of health and knowledge 2010; 5:133.Ghanizadeh A. A preliminary study on screening prevalence of pervasive developmental disorder in school children in Iran. J Autism Dev Disord 2008; 38:759-763.Nejatisafa AA, Kazemi MR, Alaghebandrad J. Autisticfeatures in adult population: evidence for continuity ofautistic symptoms with normality. Advanced in cognitivescience 2003; 5: 34-39.Khoushabi K, Pouretemad HR. Prevalence of pervasive developmental disorders according to gender in a sampleof Iranian

  13. Sodium Channel Gene Mutations in Children with GEFS+ and Dravet Syndrome: A Cross Sectional Study

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    Seyed Hassan TONEKABONI

    2013-06-01

    before age of one year and psychomotor retardation after age of two years are the most significant criteria in SCN1A mutation positive patients.References Dravet C, Bureau M, Oguni H, Fukuyama Y, Cokar O.Severe myoclonic epilepsy in infancy (Dravet syndrome. In: Roger J, Bureau M, Dravet C, Genton P, Tassinari CA, Wolf P, eds. Epileptic Syndromes in Infancy, Childhood and Adolescence, 4th  ed. London: John Libbey Eurotext Publishers; 2005. p. 89-113.Dalla Bernardina B, Colamaria V, Capovilla G, Bondavalli S. Nosological classification of epilepsies in the first three years years of life. Prog Clin Biol Res 1983;124:165-83.Commission on Classification and Terminology of the International League against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989;30:389-99.Scheffer IE, Zhang. YH, Jansen FE, Dibbens L. Dravet syndrome or genetic (generalized epilepsy with febrile seizures plus? Brain Dev 2009;31(5:394-400.Singh R, Andermann E, Whitehouse WP, Harvey AS, Keene DL, Seni MH, et al. severe myoclonic epilepsy of infancy: extended spectrum of GEFS+? Epilepsia 2001;42(7:837-44.Scheffer IE, Harkin LA, Dibbens LM, Mulley JC, Berkovic SF. Neonatal epilepsy syndromes and generalized epilepsy with febrile seizures plus (GEFS+. Epilepsia 2005;46 Suppl 10:41-7.Harkin LA, McMahon JM, Iona X, Dibbens L, Pelekanos JT, Zuberi SM, et al. The spectrum of SCN1A-related infantile enceptic encephalopathies. Brain 2007;130(Pt 3:843-52.Sun H, Zhang Y, Liang J, Liu X, Ma X, Qin, et al. Seven novel SCN1A mutations in Chinese patients with severe myoclonic epilepsy of infancy. Epilepsia 2008;49:1104-7.Miller SA, Dykes DD, polesky HF. A simple salting out procedure  for  extracting  DNA from  human  cucleated Nucleated cells. Nucleic Acids Res 1988;16(3:2115.Marini C, Scheffer IE, Nabbout R, Mei D, Cox K, Dibbens LM, et al. SCN1A duplications and deletions detected in dravet syndrome: implications for molecular diagnosis. Epilepsia 2009; 50

  14. Expression and characterization of UL16 gene from duck enteritis virus

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    Wang Mingshu

    2011-08-01

    Full Text Available Abstract Background Previous studies have indicated that the UL16 protein and its homologs from herpesvirus were conserved and played similar roles in viral DNA packaging, virion assembly, budding, and egress. However, there was no report on the UL16 gene product of duck enteritis virus (DEV. In this study, we analyzed the amino acid sequence of UL16 using bioinformatics tools and expressed in Escherichia coli Rosetta (DE3 induced by isopropy1-β-D-thiogalactopyranoside (IPTG. The recombinant protein was produced, purified using a Ni-NTA column and used to generate the polyclonal antibody against UL16. The intracellular distribution of the DEV UL16 product was carried out using indirect immunofluorescence assay. Results In our study, UL16 gene of DEV was composed of 1089 nucleotides, which encoded 362 amino acids. Multiple sequence alignment suggested that the UL16 gene was highly conserved in herpesvirus family. The UL16 gene was cloned into a pET prokaryotic expression vector and transformed into Escherichia coli Rossetta (DE3 induced by IPTG. A 60kDa fusion protein band corresponding to the predicted size was produced on the SDS-PAGE, purified using a Ni-NTA column. Anti-UL16 polyclonal sera was prepared by immunizing rabbits, and reacted with a band in the IPTG induced cell lysates with an apparent molecular mass of 60 kDa. In vivo expression of the UL16 protein in DEV infected duck embryo fibroblast cells (DEFs was localized mostly around perinuclear cytoplasmic area and in cytosol using indirect immunofluorescence assay. Conclusions The UL16 gene of DEV was successfully cloned, expressed and detected in DEV infected DEFs for the first time. The UL16 protein localized mostly around perinuclear cytoplasmic area and in cytosol in DEV infected DEFs. DEV UL16 shared high similarity with UL16 family members, indicating that DEV UL16 many has similar function with its homologs. All these results may provide some insight for further research about

  15. Psychiatric Aspects of Childhood Epilepsy

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    Raman Deep PATTANAYAK

    2012-06-01

    2004;3(11:663-72.20. Bujoreanu, IS, Ibeziako P, DeMaso DR. Psychiatric concerns in pediatric epilepsy. Child Adolesc Psychiatr Clin N Am 2010;19(2:371-86.21. Hermann BP, Lin, JJ, Jones, JE, Seidenberg S. The emerging architecture of neuropsychological impairment in epilepsy. Neurol Clin 2009;27(4:881-907.22. Hermann B, Seidenberg M, Bell B, Rutecki P, Sheth R, Ruggles K, et al. The neurodevelopmental impact of childhood-onset temporal lobe epilepsy on brain structure and function. Epilepsia 2002;43(9:1062-71.23. Loring DW, Meador KJ. Cognitive side effects of antiepileptic drugs in children. Neurology 2004;62(6:872-7.24. McDermott S, Mani S, Krishnaswami S. A populationbased analysis of specific behavior problems associated with childhood seizures. J Epilepsy 1995;8:110-8.25. Davies S, Heyman I, Goodman, R. A population survey of mental health problems in children with epilepsy. Dev Med Child Neurol 2003;45(5:292-5.26. Kaufmann R, Goldberg-Stern H, Shuper A. Attentiondeficit disorders and epilepsy in childhood: incidence, causative relations and treatment possibilities. J Child Neurol 2009;24(6:727-33.27. Buelow JM, Austin JK, Perkins SM, Shen J, Dunn DW, Fastenau PS. Behavior and mental health problems in children with epilepsy and low IQ. Dev Med Child Neurol 2003;45(10:683-92.28.Williams J, Lange B, Phillips T, Sharp GB, DelosReyes E, Bates S, et al. The course of inattentive and hyperactiveimpulsive symptoms in children with new onset seizures. Epilepsy Behav 2002;3(6:517-21.29. Hermann B, Seidenberg M, Jones J. The neurobehavioural comorbidities of epilepsy: can a natural history be developed? Lancet Neurol 2008;7(2:151-60.30. Schoenfeld J, Seidenberg M, Woodard A, Hecox K, Inglese C, Mack K, et al. Neuropsychological and behavioral status of children with complex partial seizures. Dev Med Child Neurol 1999;41(11:724-31.31. Austin JK, Caplan R. Behavioral and psychiatric comorbidities in pediatric epilepsy: toward an integrative

  16. Infantile Spasm: A Review Article

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    Mohammad Mahdi TAGHDIRI

    2014-07-01

    pres; 2009. p. 593-7.Fujii, Oquni H, Hirano Y, Shioda M, Osawa M. A longterm, clinical study on symptomatic infantile spasm with focal features. Brain Dev 2013;35(5:379-85.SankarR, Koh S, Wu J. Menkes JH. Paroxysmal disorders. In: Menkes JH, Sarnat HB,. MariaBL, editors Child neurology. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2006. p. 857-942.Kendall Nash and Joseph Sullivan. Myoclonic seizures and infantile spasms. InSwaiman KF, Ashwal S, Ferriero DM, Schor NF, editors.. Swaiman’s pediatric Neurology: principles and practice. 5th ed. Edinburgh: Elsevier Saunders; 2012. p. 774-89.Paroxysmal Disorders. In: Piña-Garza J. Fenichel’s Clinical Pediatric Neurology. 7th ed. Elsevier Saunders; 2013. p. 1-46.Paciorkowski AR, Thio LL, Dobyns WB. Genetic and biologic classification of infantile spasms. Pediatr Neurol 2011;45(6:355-67.Manqanno S, Nardello R, Tripi G, Giordano G, Spitaleri C, Manfano GR. West Syndrome Followed by juvenile myoclonic epilepsy: a coincidental occurrence. BMC Neural 2013;13:48.LUX AL. Latest American and European update on infantile spasms. Curr Neural Neurosci Rep 2013;13(3:334.Hrachovy RA, Frost JD Jr. Infantile spasms. Handb Clin Neuro. 2013;111:611-8.Shumiloff NA, Lam WM, Manasco KB. Adrenocorticotropic hormone for the treatment of west syndrome in children. Ann Pharmacother 2013 47(5:744- 54.Wheless JW, Gibson PA, Rosbeck KL, Hardin M, O’Dell C, Whiltemore V. Infantile Spasms (west syndrome:  Update and resources for pediatricians and providers to share with parents. BMC Pediatr. 2012;12:108.Watemberg N. Infantile Spasms: treatment challenges. Curr Treat Options Neural. 2012;14(4: 322-31.Fukui M, Shimakawa S, Tanabe T, Nomura S, Kashiwagi M, Azumakawa K. Partial seizures during ACTH therapy in a cryptogenic West syndrome patient. Brain Dev 2013;Pii:s0387-7604(1300003-x.Friedman D, Boqner M, Parker-Menzer K, Dviskyo. Vigabatin for partial- onset seizure treatment in patients with tuberous sclerosis complex. Epilepsy Behav 2013

  17. Clinical and Para clinical Manifestations of Tuberous Sclerosis: A Cross Sectional Study on 81 Pediatric Patients

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    Seyyed Hassan TONEKABONI

    2012-09-01

    -9.Lendvay TS, Marshall FF. The tuberous sclerosis complex and its highly variable manifestations. J Urol2003 May;169(5:1635-42.Curatolo P, Jóźwiak S, Nabbout R; on behalf of the participants of the TSC Consensus Meeting for SEGA and Epilepsy Management. Management of epilepsy associated with tuberous sclerosis complex (TSC:Clinical recommendations. Eur J Paediatr Neurol 2012Jun;16(1:83-5.Jansen FE, Van Huffelen AC, Van Rijen PC, LeijtenFS,Jennekens-Schinkel A, Gosselaar P et al. Epilepsy surgeryin tuberous sclerosis: the Dutch experience. Seizure 2007Jul;16(5:445-53.Turgut M, Akalan N, Ozgen T, Ruacan S, Erbengi A. Subepandymal giant cell astrocytoma associated with tuberous sclerosis: diagnostic and surgical characteristics of five cases with unusual features. Clin Neurol Neurosurg1996 Aug;98(3:217-21.Coppola G, Klepper J, Ammendola E, Fiorillo M, dellaCorte, Capano G. The effects of the ketogenic diet in refractory partial seizures with reference to tuberous sclerosis. Eur J Pediatr Neurol 2006 May;10(3:148-51.Jozwia S, Kotulska K, Domanska-Pakiela D, LojszczykB, Syczewska M et al. Antiepileptic treatment before the onset of seizure reduces epilepsy severity and risk of mental retardation in infants with tuberous sclerosis complex. Eur J Paediatr Neurol 2011 Sep;15(5:424-31.Konishi Y, Ito M, Okuno T, Hojo H, Okuda R, Nakano Yet al. Tuberous sclerosis: early neurologic manifestations and CT features in 18 patients. Brain Dev 1979;1(1:31-7.Gerard G, Weisberg L. Tuberous sclerosis: CT findings and differential diagnosis. Comput Radiol 1987 Jul-Aug;11(4:189-92.Pompili G, Zirpoli S, Sala C, Flor N, Alfano RM, Volpi A et al. Magnetic resonance imaging of renal involvementin genetically studied patients with tuberous sclerosis complex. Eur J Radiol 2009 Nov;72(2:335-41.Fleury P, de Groot Wp, Delleman JW, Verbeeten B Jr,Frankenmolen-Witkiezwicz IM. Tuberous sclerosis: theincidence of sporadic cases versus familial cases. BrainDev 1980;2(2:107-17.Saadat M, Ansari-Lari M, Farhud

  18. A study of effect of Nigella sativa oil in paracetamol induced hepatotoxicity in albino rats

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    Manik S. Ghadlinge

    2014-06-01

    Conclusion: This study demonstrated that NS oil has hepatoprotective effect. NS oil administration can prevent or reverse the hepatotoxicity induced by paracetamol. [Int J Basic Clin Pharmacol 2014; 3(3.000: 539-546

  19. Evaluation of anti-leishmanial activity of artemisinin combined with amphotericin B or miltefosine in Leishmania donovani promastigotes

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    Musfikur Rahaman

    2014-08-01

    Conclusions: This study supports the combination use of artemisinin-amphotericin B and artemisinin-miltefosine, worthy of future pharmacological consideration. [Int J Basic Clin Pharmacol 2014; 3(4.000: 644-648

  20. Wound healing suppressant effect of vincristine reversed by vitamin A: an experimental study

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    Venkatadri T.V.

    2016-06-01

    Conclusions: Vitamin A by itself produced little effect on healing except a modest increase in granulation mass. But it significantly reversed the healing suppressant effects of vincristine. [Int J Basic Clin Pharmacol 2016; 5(3.000: 962-964

  1. A study to assess the effect of vitamin D supplementation on insulin resistance and glycaemic control in type 2 diabetes mellitus patients

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    Parminder K. Dhillon

    2016-04-01

    Conclusions: The study showed that vitamin D supplementation improves the glycaemic control and insulin sensitivity in type 2 diabetes mellitus patients. [Int J Basic Clin Pharmacol 2016; 5(2.000: 466-472

  2. The Use of Patient-Specific Intra-Operative Guides for Total Knee Arthroplasty (TKA

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    Hendrik P. Delport

    2012-08-01

    Conclusions: We conclude that this novel technique hereby described has major benefits: less operative time and proper implant positioning, but more prospective studies are mandatory. [Arch Clin Exp Surg 2012; 1(4.000: 206-212

  3. Awareness of adverse drug reactions in third M.B.B.S students practicing self-medication

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    Shreyas R. Burute

    2016-02-01

    Conclusions: Considering the wide range of drugs consumed, the numbers of ADRs mentioned were few and their spectrum limited indicating scope for improvement. [Int J Basic Clin Pharmacol 2016; 5(1.000: 196-201

  4. Disease: H00045 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available lity of Ki-67 as a prognostic marker in pancreatic endocrine neoplasms. Am J Clin Pathol 109:245-7 (1998) (drug) Skeel RT (ed). Handb...ook of Cancer Chemotherapy, Sixth Edition Lippincott Williams & Wilkins (2003) ...

  5. Expanding n-gram training data for language models based on morpho-syntactic transformations

    OpenAIRE

    Verwimp, Lyan; Pelemans, Joris; Hamme, Hugo Van; Wambacq, Patrick

    2015-01-01

    Verwimp L., Pelemans J., Van hamme H., Wambacq P., ''Expanding n-gram training data for language models based on morpho-syntactic transformations'', Computational linguistics in the Netherlands journal (CLIN journal), vol. 5, pp. 49-64, 2015.

  6. Disease: H00322 [KEGG MEDICUS

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    Full Text Available ettsial infections--a threat to travellers? Curr Opin Infect Dis 17:433-7 (2004) PMID:15546086 Jensenius M, ...Fournier PE, Raoult D Rickettsioses and the international traveler. Clin Infect D

  7. Disease: H00854 [KEGG MEDICUS

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    Full Text Available H00854 Wolfram syndrome (WFS); DIDMOAD syndrome Wolfram syndrome (WFS) is a rare hereditary neur ... rophy: a study of Wolfram syndrome in the Lebanese population . J Clin Endocrinol Metab 89:1656-61 (2004) PMID:20 ...

  8. A cross-sectional study on knowledge, attitude, and behavior related to antibiotic use among undergraduate medical students in a tertiary care medical college, Kashmir

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    Shakeel Ahmad Mir

    2015-12-01

    Conclusions: There is an urgent need to improve education on antibiotic use in medical curricula. Furthermore, strict policies must be enforced to regulate dispensing of antibiotics. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1156-1162

  9. Effect of co-administration of voglibose and vildagliptin on diabetic albino rats

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    Umashanker PD Keshri

    2016-08-01

    Conclusions: Vildagliptin and voglibose are effective in lowering blood glucose level in albino diabetic rats but their combination has potentiating effect. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1533-1538

  10. Drug utilization pattern of analgesics in various departments of a tertiary care teaching rural dental hospital

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    Nirav N. Patel

    2014-10-01

    Conclusions: Drug utilization data can help to formulate appropriate clinical guidelines for drug use and facilitate rational use of medicines in population. [Int J Basic Clin Pharmacol 2014; 3(5.000: 804-806

  11. The practice-unit centered clinical database--the implementation.

    OpenAIRE

    Bryner, U. M.

    1991-01-01

    A clinical database system under the name ClinTrac has been developed for the purpose of acquiring, processing, storing, analyzing, and communicating clinical information. The core of this system consists of a practice-unit centered database.

  12. Health screening - men - ages 40 to 64

    Science.gov (United States)

    ... on Colorectal Cancer, and the American College of Radiology. CA Cancer J Clin . 2008;58:130-60. ... chap 42. Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement. Moyer VA; U.S. Preventive ...

  13. Health screening - men age 65 and older

    Science.gov (United States)

    ... on Colorectal Cancer, and the American College of Radiology. CA Cancer J Clin . 2008;58:130-160. ... chap 42. Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement. Moyer VA; U.S. Preventive ...

  14. Comparative study to evaluate the anti-diabetic activity of commercially available extract of Tinospora cordifolia and Phyllanthus emblica in streptozocin induced diabetic rat

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    Nishant Pathak

    2016-08-01

    Conclusions: Commercially available extract of Tinospora cordifolia and Phyllanthus emblica have significant anti-diabetic activity in streptozocin induced diabetic rats. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1641-1646

  15. Genetics Home Reference: epidermolysis bullosa simplex

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    ... mutations: new phenotypes and new mutations. Br J Dermatol. 2013 Apr;168(4):808-14. doi: 10. ... epidermolysis bullosa: new diagnostic criteria and classification. Clin Dermatol. 2012 Jan-Feb;30(1):70-7. doi: ...

  16. Genetics Home Reference: familial pityriasis rubra pilaris

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    ... review of diagnosis and treatment. Am J Clin Dermatol. 2010;11(3):157-70. doi: 10.2165/ ... Srivastava G. (Juvenile) Pityriasis rubra pilaris. Int J Dermatol. 2006 Apr;45(4):438-46. Review. Citation ...

  17. Genetics Home Reference: nonbullous congenital ichthyosiform erythroderma

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    ... congenital ichthyosiform erythroderma and lamellar ichthyosis. Clin Exp Dermatol. 2003 May;28(3):235-40. Review. Citation ... ichthyoses: the underlying genetic defects and pathomechanisms. J Dermatol Sci. 2006 May;42(2):83-9. Epub ...

  18. Sunburn

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    ... HI. Management of acute sunburn. Am J Clin Dermatol . 5(1):39-47, 2004. Last Updated: 22 ... these advertising practices and to make choices about online behavioral advertising, please click here . This site complies ...

  19. Disease: H00352 [KEGG MEDICUS

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    Full Text Available J Clin Microbiol Infect Dis 30:1151-8 (2011) PMID:20708091 (description, drug) Desnues B, Al Moussawi K, Fenolla...(2010) PMID:18291339 (description, drug) Schneider T, Moos V, Loddenkemper C, Marth T, Fenolla

  20. Disease: H00034 [KEGG MEDICUS

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    Full Text Available H00034 Carcinoid Carcinoid tumors are relatively uncommon neoplasms that nonetheless comprise up ... Eick G, Chan AK. Gastrointestinal carcinoids: the evolution ... of diagnostic strategies. J Clin Gastroenterol 40: ...

  1. Crinum zeylanicum memory enhancing effect is mediated via central cholinergic transmission system

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    Tijani Adeniyi Yahaya

    2015-10-01

    Conclusion: The extract, as well as its partially purified alkaloid, possesses potential that may be employed for therapeutic management of Alzheimer's disease. [Int J Basic Clin Pharmacol 2015; 4(5.000: 864-868

  2. Disease: H00292 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available R, Woo A, Ralph-Edwards A, Butany J Hypertrophic cardiomyopathy: current understanding and treatment objec...tives. J Clin Pathol 62:226-35 (2009) PMID:19568388 (drug) Marian AJ Contemporary t

  3. Evaluation of anti-psychotic effect of nimodipine using methylphenidate as a model to induce psychosis in albino mice

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    Hemant Tanwani

    2015-12-01

    Conclusions: Methylphenidate has potential to be used as an alternative model for inducing psychosis in animals and nimodipine shows promising results for use as adjuvant antipsychotic drug. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1047-1053

  4. Hepatoprotective activity of methanolic leaves extract of Rostellularia procumbens by using carbon tetrachloride intoxicated rats

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    M. Mamatha

    2014-12-01

    Conclusion: The results confirm that R. procumbens have hepatoprotective activity against CCl4 induced hepatotoxicity and significant hepatoprotection seen at 500 mg/kg dose. [Int J Basic Clin Pharmacol 2014; 3(6.000: 964-969

  5. Evaluation of anticonvulsant activity of ACE inhibitors (imidapril and quinapril in experimentally induced animal models of epilepsy

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    Pushpa VH

    2016-06-01

    Conclusions: Quinapril and imidapril in a dose dependent manner showed increase in antiepileptic activity, imidapril has better antiepileptic activity when compared to quinapril. [Int J Basic Clin Pharmacol 2016; 5(3.000: 798-801

  6. Prescription and cost-analysis of antiemetic medication use in pediatric wards: a prospective observational study

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    Maulik M. Patel

    2014-02-01

    Conclusions: Gastroenteritis was most frequent indication for use of anti-emetics. Domperidone pharmacotherapy was cheaper and most frequently prescribed than ondansetron. [Int J Basic Clin Pharmacol 2014; 3(1.000: 124-129

  7. A randomized, open-labelled study of the sedative, analgesic and anxiolytic effect of dexmedetomidine and tramadol in postoperative patients

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    Padma L

    2013-12-01

    Conclusion: Though there is no statistical difference in both groups, dexmedetomidine significantly reduced anxiety, agitation and produced calmness in postoperative patients which was not seen with tramadol. [Int J Basic Clin Pharmacol 2013; 2(6.000: 804-809

  8. Eye of horus and ndash; Erratum revealed a prescription survey

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    M. J. Jijin

    2014-12-01

    Conclusions: The present data shows most prescriptions in the study was inadequate and important details were lacking, legibility of prescription was poor in rating. [Int J Basic Clin Pharmacol 2014; 3(6.000: 1016-1019

  9. Comparison of cardiovascular safety of escitalopram and sertraline based on electrocardiographic alterations: a pharmacovigilance study

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    Balwant K. Choure

    2016-08-01

    Conclusions: It was concluded, at therapeutic doses neither of the drugs have the potential risk of drug induced arrhythmias, throughout the study. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1193-1200

  10. A study on drug prescribing pattern in psychiatry out-patient department from a tertiary care teaching hospital

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    Sonali B. Rode

    2014-06-01

    Conclusion: Utilization pattern of the psychotropic drugs were in accordance to the recommendations of various treatment guidelines. BZD were the most commonly prescribed psychotropic drugs. [Int J Basic Clin Pharmacol 2014; 3(3.000: 517-522

  11. Genetics Home Reference: X-linked agammaglobulinemia

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    ... Modell Foundation: National Primary Immunodeficiency Resource Center National Organization for Rare Disorders : ... V, Aiba Y, Shurtleff SA, Kurosaki T. A minimally hypomorphic mutation in Btk resulting in reduced B cell numbers but no clinical disease. Clin Exp Immunol. ...

  12. Evaluation of antidepressant activity of ondansetron alone and in combination with fluoxetine-an experimental study

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    Sonal M. Parekar

    2016-02-01

    Conclusions: Our study concludes that ondansetron alone and in combination with fluoxetine possesses significant antidepressant activity in animal models of depression. [Int J Basic Clin Pharmacol 2016; 5(1.000: 90-97

  13. Anti-inflammatory potential of Agaricus in carrageenan-induced model of local inflammation in rats

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    Abdelrazzag A. Elmajdoub

    2015-06-01

    Conclusions: These data may indicate that Agaricus extract has the potential of anti-inflammatory activity that could be applied in acute inflammatory disorders. [Int J Basic Clin Pharmacol 2015; 4(3.000: 497-502

  14. Disease: H00161 [KEGG MEDICUS

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    Full Text Available SH: D019082 OMIM: 270400 PMID:18285838 Porter FD Smith-Lemli-Opitz syndrome: pathogenesis, diagnosis and man...Opitz syndrome. Clin Genet 68:383-91 (2005) PMID:15670717 Correa-Cerro LS, Porter

  15. Prolactinoma

    Science.gov (United States)

    ... JK. Update on prolactinomas. Part 2: Treatment and management strategies. J Clin Neurosci . 2015;22:1568-1574. PMID: 26243714 ... by: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University ...

  16. Pharmacokinetics and clinical evaluations of gentamicin-induced nephrotoxicity in puppies

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    Fidelis A. Gberindyer

    2015-08-01

    Conclusion: These suggest the risk of nephrotoxicity following treatment with gentamicin beyond 5 consecutive days irrespective of the dosing interval in puppies. [Int J Basic Clin Pharmacol 2015; 4(4.000: 691-696

  17. Disease: H00373 [KEGG MEDICUS

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    Full Text Available D:16288402 (description, drug) Nalca A, Rimoin AW, Bavari S, Whitehouse CA Reemergence of monkeypox: preva...lence, diagnostics, and countermeasures. Clin Infect Dis 41:1765-71 (2005) PMID:176

  18. Disease: H00304 [KEGG MEDICUS

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    Full Text Available onjugate vaccine in the United Kingdom. Clin Ther 34:385-99 (2012) PMID:20980793 (drug) Fitzwater SP, Watt J...1990) PMID:22244051 (drug) Ladhani SN Two decades of experience with the Haemophilus influenzae serotype b c

  19. Portulaca oleracea inhibit vincristine induced peripheral neuropathy: involvement of ATP-sensitive K+ channels

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    L. Mohana Rupa

    2014-06-01

    Conclusion: The results of the present study reveal the antinociceptive effect of P. oleracea in vincristine induced peripheral neuropathy and involving ATP-sensitive potassium channels pathway. [Int J Basic Clin Pharmacol 2014; 3(3.000: 474-478

  20. Evaluation of neuroprotective effect of flupirtine in brain of albino rats

    Directory of Open Access Journals (Sweden)

    Elango P

    2016-02-01

    Conclusions: This study represents the neuroprotective characteristics of flupiritne against the excitotoxicity induced by NMDA in an in vivo rat models. [Int J Basic Clin Pharmacol 2016; 5(1.000: 135-141

  1. To evaluate and compare the hypoglycemic, antioxidant and hypolipidemic effect of lycopene with atorvastatin in hyperlipidemic New Zealand white rabbits

    Directory of Open Access Journals (Sweden)

    Sarita Mulkalwar

    2015-02-01

    Conclusion: Findings suggest that lycopene may have considerable therapeutic benefit as an antioxidant and hypolipidemic agent, but may not be effective as a hypoglycemic agent. [Int J Basic Clin Pharmacol 2015; 4(1.000: 148-152

  2. 20 healthy snacks with 100 calories or less

    Science.gov (United States)

    ... Rolls BJ. Serving a variety of vegetables and fruit as a snack increased intake in preschool children. Am J Clin Nutr U.S. Department of Health & Human Services (DHHS). National Institute for Health. We ...

  3. Interaction of two memory enhancing herbal drugs Memory Plus and Mentat with diazepam and phenytoin sodium in mice

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    Neera R. Gupta

    2015-04-01

    Conclusion: Subchronic administration of MP and Mentat shows significant interaction with diazepam and PS. Further human studies are warranted to confirm these findings. [Int J Basic Clin Pharmacol 2015; 4(2.000: 203-207

  4. Genetics Home Reference: polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy

    Science.gov (United States)

    ... diagnosed in more than 100 people in the Japanese population. Although affected individuals have been reported worldwide, ... report of five cases and review of the literature. Clin Orthop Relat Res. 2007 Jan;454:262- ...

  5. Effects of sildenafil on lipid profile and glycemic control in patients with type 2 diabetes mellitus and metabolic syndrome

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    Haedar Abdulhafith Al-biati

    2014-12-01

    Conclusion: We have provided the first evidence that sildenafil therapy improve glycemic control, lipid profile and body mass index in diabetic patients with metabolic syndrome. [Int J Basic Clin Pharmacol 2014; 3(6.000: 1048-1051

  6. Comparative efficacy of inhaled ciclesonide, budesonide, and fluticasone in mild to moderately persistent bronchial asthma

    Directory of Open Access Journals (Sweden)

    Tamoghna Maiti

    2014-10-01

    Conclusion: Steroid therapy along with beta2-agonists showed a significant improvement in symptoms. There was no difference among the three different types of steroids. [Int J Basic Clin Pharmacol 2014; 3(5.000: 836-839

  7. Effect of trimetazidine on acute and sub-acute models of inflammation in male wistar rats

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    Naveena R

    2016-06-01

    Conclusions: Results of the study indicate that trimetazidine can reduce the complications of atherosclerosis which involves inflammation as the major steps in its pathogenesis. [Int J Basic Clin Pharmacol 2016; 5(3.000: 782-787

  8. Disease: H00156 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available osity. Clin Exp Nephrol 11:174-9 (2007) PMID:15630634 Smelt AH, de Beer F Apolipoprotein E and familial dysbetalipoproteinemia: clini...cal, biochemical, and genetic aspects. Semin Vasc Med 4:249-57 (2004) ...

  9. Disease: H01360 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available on disease, present treatments and future prospects. Int Immunopharmacol 11:1646-62 (2011) PMID:18360551 (e...ar R Allergic rhinitis: current options and future perspectives. Curr Opin Allergy Clin Immunol 14:168-76 (2014) ...

  10. Pattern of use of antibiotics in hospitalized patients in the medicine department of a tertiary care hospital

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    Muniza Bai

    2015-10-01

    Conclusion: Ceftriaxone, doxycycline, and metronidazole are commonly used antibiotics and significant proportion of the cost of drugs is spent for antimicrobials in a medicine unit. [Int J Basic Clin Pharmacol 2015; 4(5.000: 888-894

  11. Genetics Home Reference: familial atrial fibrillation

    Science.gov (United States)

    ... or Free article on PubMed Central Roberts R. Mechanisms of disease: Genetic mechanisms of atrial fibrillation. Nat Clin Pract Cardiovasc Med. ... with a qualified healthcare professional . About Genetics Home Reference Site Map Contact Us Selection Criteria for Links ...

  12. Genetics Home Reference: congenital hyperinsulinism

    Science.gov (United States)

    ... Z, Arya VB, Hussain K. Hyperinsulinaemic hypoglycaemia:genetic mechanisms, diagnosis and management. J Clin Res Pediatr Endocrinol. ... Shyng SL, Stanley CA. Clinical characteristics and biochemical mechanisms of congenital hyperinsulinism associated with dominant KATP channel ...

  13. An open-label study to assess the effect of a single dose of Nebivolol and Ivabradine on heart rate and pulse wave velocity in hypertensive patients receiving amlodipine

    Directory of Open Access Journals (Sweden)

    Rama Mohan Pathapati

    2015-04-01

    Conclusions: Nebivolol is an effective HR lowering agent compared to Ivabradine. However, significant decrease in arterial stiffness was observed with Ivabradine. [Int J Basic Clin Pharmacol 2015; 4(2.000: 219-223

  14. Disease: H00964 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00964 Thiopurine S-methyltransferase deficiency (TPMT deficiency) Thiopurine S-methyltransferas ... rting thiopurine drug treatment; a pharmacogenomic test ... whose time has come. J Clin Pathol 63:288-95 (2010 ...

  15. Evaluation of second year MBBS students perceptions and experiences towards tutorials as a teaching-learning method in pharmacology

    Directory of Open Access Journals (Sweden)

    Ravindra S. Beedimani

    2016-06-01

    Conclusions: The suggestions based on feedback from learners, should be kept in mind while conducting tutorials to make it fruitful experience for MBBS students. [Int J Basic Clin Pharmacol 2016; 5(3.000: 1112-1117

  16. Disease: H01041 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available s to gram-positive coccus. Most infections are mild, but fatal infections such as endocarditis with high rat...ococcus urinae: severe and fatal bloodstream infections and endocarditis. J Clin

  17. Antidiabetic effect of 2 nitro benzimidazole in alloxan induced diabetic rats

    Directory of Open Access Journals (Sweden)

    Prapthi Bathini

    2013-12-01

    Conclusion: 2 nitro benzimidazole exhibited significant antihyperglycemic activity in alloxan-induced diabetic rats comparable to that of the standard drug glibenclamide. [Int J Basic Clin Pharmacol 2013; 2(6.000: 814-818

  18. Evaluation of analgesic activity of Aegle marmelos steam bark in experimental animals

    Directory of Open Access Journals (Sweden)

    Sarang Gajanan Ghodki

    2016-06-01

    Conclusions: AMSBAE has analgesic activity. The analgesic activity of AMSBAE was comparable to that of tramadol and Aspirin. Hence, AMSBAE could be a possible alternative to NSAIDs. [Int J Basic Clin Pharmacol 2016; 5(3.000: 1081-1086

  19. Role of glipizide therapy on oxidative stress parameters in the patient with Type-II diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Prakash P. Malam

    2014-12-01

    Conclusion: Glipizide therapy significantly reduced oxidative free radicals and increased antioxidant mechanism, which reduced oxidative stress, progression DM-II and its related complication. [Int J Basic Clin Pharmacol 2014; 3(6.000: 995-999

  20. Disease: H00485 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00485 Robinow syndrome Robinow syndrome is characterized by distinctive craniofacial...hn MT, Cunningham ML, Petryk A, Lohr JL Craniofacial and intraoral phenotype of Robinow syndrome forms. Clin Genet 80:15-24 (2011) ...

  1. The efficacy and safety of clomiphene citrate and metformin on ovulation induction in patients suffering from anovulatory infertility

    Directory of Open Access Journals (Sweden)

    Hardik Patel

    2015-12-01

    Conclusion: Ovulation rate was significantly higher compared to pregnancy rate. We could not find any benefit of adding metformin to the standard treatment with clomiphene citrate. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1241-1246

  2. An overview of drugs approved in India from 1999 through 2015

    Directory of Open Access Journals (Sweden)

    Vihang S. Chawan

    2015-08-01

    Conclusions: Thus, the present study highlights the changing scenario of drug approval, with few drugs being approved for clinical practice in the last 3 years. [Int J Basic Clin Pharmacol 2015; 4(4.000: 697-700

  3. Evaluation of pharmacology teaching-learning methods in a government medical college

    Directory of Open Access Journals (Sweden)

    Aritra Ghosh

    2016-02-01

    Conclusions: This study helps in knowing students' opinion and preferences in curriculum to make it more interesting and aids to modify the undergraduate Pharmacology teaching pattern. [Int J Basic Clin Pharmacol 2016; 5(1.000: 126-130

  4. Disease: H00384 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available : A95 MeSH: D015004 MedlinePlus: 001365 PMID:17304460 (description, drug) Barnett ED Yellow fever: epidemi...ology and prevention. Clin Infect Dis 44:850-6 (2007) PMID:21798462 (description) J

  5. An analysis of prescription pattern and adverse drug reaction profile in children treated with antiepileptic drugs in a tertiary care teaching hospital

    Directory of Open Access Journals (Sweden)

    Meenakshi B.

    2016-04-01

    Conclusions: ADRs were more common in patients with combination therapy which insists the need for a newer AED with less toxicity especially for paediatric patients. [Int J Basic Clin Pharmacol 2016; 5(2.000: 389-393

  6. Impact of teaching session on concepts of palliative care in medical undergraduates.

    Directory of Open Access Journals (Sweden)

    Sirisha Annavarapu

    2016-02-01

    Conclusions: Concept of palliative care was poor among medical undergraduates. Health care providers can overcome by knowledge construction, interrelation between practice and evidence based medicine. [Int J Basic Clin Pharmacol 2016; 5(1.000: 188-191

  7. Isolation, identification, and antibiogram studies of Salmonella species and Escherichia coli from boiler meat in some selected areas of Bangladesh

    Directory of Open Access Journals (Sweden)

    Abu Saim Al-Salauddin

    2015-10-01

    Conclusions: The study revealed the presence of multidrug resistant Salmonella and E. coli in broiler meat sold in live bird market of different upazilla. [Int J Basic Clin Pharmacol 2015; 4(5.000: 999-1003

  8. Disease: H01049 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available imi LA, Yawetz S, Lasker BA, Bolcen SJ, Brown JM, Marty FM Gordonia bronchialis bacteremia and pleural infection: case report and rev...iew of the literature. J Clin Microbiol 49:1662-6 (2011) ...

  9. Disease: H01057 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available gon BL Gnathostomiasis: a review of a previously localized zoonosis now crossing ...actor) Rusnak JM, Lucey DR Clinical gnathostomiasis: case report and review of the English-language literature. Clin Infect Dis 16:33-50 (1993) ...

  10. Medications package inserts' usefulness to doctors and patients: Sudanese doctors perspective

    Directory of Open Access Journals (Sweden)

    Kamal Addin Mohammad Ahmad Idris

    2014-08-01

    Conclusion: Doctors should give more attention to their patients' medication information specific needs, advice and motivate them to read the PIs before using their medications. [Int J Basic Clin Pharmacol 2014; 3(4.000: 718-722

  11. Disease: H00084 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available bone marrow transplant. Annu Rev Med 54:29-52 (2003) PMID:15931364 (drug) Iwasaki T. Recent advances in the treatment of graft-versus-host disease. Clin Med Res 2:243-52 (2004) ...

  12. Role of free radical scavengers in oral malignancies treated with radiotherapy

    Directory of Open Access Journals (Sweden)

    Virendra Kushwaha

    2013-12-01

    Conclusion: These findings indicated the protective role of antioxidants against free radicals produced in oral malignancies treated with radiotherapy. [Int J Basic Clin Pharmacol 2013; 2(6.000: 735-741

  13. Comparison of efficacy of telmisartan with losartan in patients of essential hypertension with cognitive impairment

    Directory of Open Access Journals (Sweden)

    Nitin Natthuji Puram

    2016-06-01

    Conclusions: Telmisartan is as effective as losartan in controlling blood pressure and improving cognitive function in hypertensive patients with cognitive impairment. [Int J Basic Clin Pharmacol 2016; 5(3.000: 702-706

  14. Disease: H00579 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 94725 (description, gene) Gubler MC Inherited diseases of the glomerular basement... membrane. Nat Clin Pract Nephrol 4:24-37 (2008) PMID:21071975 (description, gene) Kashtan CE, Segal Y Genetic disorders of glomerula

  15. Comparative evaluation of H1 receptor blocking activity and safety of newer H1antagonist mizolastine with loratadine and placebo: a randomized double blind three way crossover study

    Directory of Open Access Journals (Sweden)

    K. Swarnalatha

    2016-06-01

    Conclusions: Mizolastine has good antihistaminic activity than loratadine. Neither drug causes any psychomotor impairment or has anti-cholinergic action. [Int J Basic Clin Pharmacol 2016; 5(3.000: 661-675

  16. Investigation of in vitro Mineral Forming Bacterial Isolates from Subgingival Calculus

    Directory of Open Access Journals (Sweden)

    Turgut Demir

    2014-06-01

    This is the first report to identify and show that bacteria from subgingival calculus under anaerobic conditions are involved in the formation of dental calculus. [Arch Clin Exp Surg 2014; 3(3.000: 153-160

  17. Effect of Lagenaria siceraria fruit extract (Bottle gourd on hepatotoxicity induced by antitubercular drugs in albino rats

    Directory of Open Access Journals (Sweden)

    Satyajeet K. Funde

    2013-12-01

    Conclusion: Ethanolic extract of Lagenaria siceraria fruit possesses significant hepatoprotective and antioxidant activity in antitubercular drugs induced hepatotoxicity. [Int J Basic Clin Pharmacol 2013; 2(6.000: 728-734

  18. Effect of oxytetracycline and doxycycline on muscle tone in healthy human volunteers

    Directory of Open Access Journals (Sweden)

    Savitri Katlam

    2016-08-01

    Conclusions: Use of oxytetracycline is associated with reduced grip strength in healthy human volunteers. These findings have potential implication on the functional ability of muscle. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1559-1562

  19. Comparison of the acute effects of hemostatic agents on neural tissues in spine surgery: Histologic analysis in rat models

    Directory of Open Access Journals (Sweden)

    Gokhan Meric

    2016-03-01

    Conclusion: Both gelatin sponge and oxidized cellulose did not increase the cellular necrosis of neural tissues. However, oxidized cellulose may lead to an increased local inflammatory reaction. [Arch Clin Exp Surg 2016; 5(1.000: 21-26

  20. Analgesic and antioxidant activities of the methanolic extract of Operculina turpethum leaves in mice

    Directory of Open Access Journals (Sweden)

    Maxwell I. Ezeja

    2015-06-01

    Conclusion: The study showed that O. turpethum possesses analgesic and antioxidant properties and confirmed the folkloric use of O. turpethum leaves in the traditional pain management. [Int J Basic Clin Pharmacol 2015; 4(3.000: 453-457

  1. Soy Allergy

    Science.gov (United States)

    ... cheese, soy fiber, soy flour, soy grits, soy ice cream, soy milk, soy nuts, soy sprouts, soy yogurt) ... Kaeding AJ, Matsui EC, Wood RA. The natural history of soy allergy. J Allergy Clin Immunol, 2010; ...

  2. Randomised Clinical Efficacy Trial of Topiramate and Nitrazepam in Treatment of Infantile Spasms

    Directory of Open Access Journals (Sweden)

    Razieh FALLAH

    2014-01-01

    . A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: a report of the ILEA task force on classification and terminology. Epilepsia 2001; 42(6:796–803.Riikonen RS. Favourable prognostic factors with infantile spasms. Eur J Paediatr Neurol 2010;14(1:13-18.Lagae L, Verhelst H, Ceulemans B, De Meirleir L, Nassogne MC, De Borchgrave V, et al. Treatment and long term outcome in West syndrome: the clinical reality. A multicentre follow up study. Seizure 2010;19(3:159-64.Fois A. Infantile spasms: review of the literature and personal experience. Ital J Pediatr 2010;36:15-21.Jaseja H. Justification of vigabatrin administration in West syndrome patients? Warranting a re-consideration for improvement in their quality of life. Clin Neurol Neurosurg 2009;111(2:111-14.Hwang H, Kim KJ. New antiepileptic drugs in pediatric epilepsy. Brain Dev 2008,30(9;549–55.Mikaeloff Y, de Saint-Martin A, Mancini J, Peudenier S, Pedespan JM, Vallée L, et al. Topiramate: efficacy and tolerability in children according to epilepsy syndromes. Epilepsy Res 2003;53(3:225-32.Peltzer B, Alonso WD, Porter BE. Topiramate and Adrenal-Cortico-tropic Hormone as Initial Treatment of Infantile Spasms. J Child Neurol 2009;24(4:400-5.Zou LP, Lin Q, Qin J, Cai FC, Liu ZS, Mix E. Evaluation of open-label topiramate as primary or adjunctive therapy in infantile spasms. Clin Neuropharmacol 2008;31(2:86-92.Korinthenberg R, Schreiner A. Topiramate in children with west syndrome: a retrospective multicenter evaluation of 100 patients. J Child Neurol 2007;22(3:302-6.14. Kwon YS, Jun YH, Hong YJ, Son BK. Topiramate monotherapy in infantile spasm. Yonsei Med J 2006;47(4:498-504.Hosain SA, Merchant S, Solomon GE, Chutorian A. Topiramate for the treatment of infantile spasms. J Child Neurol 2006;21(1:17-9.Glauser TA, Clark PO, McGee K. Long-term response to topiramate in patients with West syndrome. Epilepsia 2000;41(Suppl. 1:S91-4.Albsoul-Younes AM, Salem HA, Ajlouni SF, Al-Safi SA

  3. Frequency, Causes, and Findings of Brain CT Scans of Neonatal Seizure at Besat Hospital, Hamadan, Iran

    Directory of Open Access Journals (Sweden)

    Fateme EGHBALIAN*

    2015-01-01

    . Clin perinatal 2005; 24: 735-772.Lanska MJ, Lanska DJ, Baumann RJ, Kryscio RJ. A population-based study of neonatal seizures in Fayette County, Kentucky. Neurology 1995; 45:724-32.Ronen GM, Penney S, Andrews W. The epidemiology of clinical neonatal seizures in Newfoundland: a populationbased study. J Pediatr 1999; 134:71-5.Saliba RM, Annegers JF, Waller DK, et al. Incidence of neonatal seizures in Harris County, Texas, 1992-1994. Am J Epidemiol 1999; 150:763-9.Volpe JJ. Neonatal seizures. In: Neurology of the newborn. 5th ed. Philadelphia: WB Saunders. 2008. P. 203-44.Fanaroff AA, Martin RJ, Neonatal. Prenatal medicine. 8th ed. New York: Mosby, 2006; 956-976.Scher MS, Aso K, Beggarly ME, et al. Electrographic seizures in preterm and full-term neonates: clinical correlates, associated brain lesions, and risk for neurologic sequelae. Pediatrics 1993; 91:128-34.Tekgul H, Gauvreau K, Soul J, et al. The current etiologic profile and neurodevelopmental outcome of seizures in term newborn infants. Pediatrics 2006; 117:1270-80.Rogalski LI, Minokoshi M, Silveira DC, Cha BH, Holmes GL. Recurrent neonatal seizures: relationship of pathology to the electroencephalogram and cognition. Brain Res Dev Brain Res 2001; 129:27-38.Cilio MR, Sogawa Y, Cha BH, Liu X, Huang LT, Holmes GL. Long-term effects of status epilepticus in the immature brain are specific for age and model. Epilepsia 2003; 44:518-28.Lynch M, Sayin U, Bownds J, Janumpalli S, Sutula T. Long-term consequences of early postnatal seizures on hippocampal learning and plasticity. Eur J Neurosci 2000; 2:2252-64.Ni H, Jiang YW, Bo T, Wang JM, Wu XR. c-Fos, N-methyl-Diaspartate receptor 2C, GABA-A-a1 immunoreactivity, seizure latency, and neuronal injury following single or recurrent neonatal seizures in hippocampus of Wistar rat. Neurosci Lett 2005; 380:149-54.Bo T, Jiang Y, Cao H, Wang J, Wu X. Long-term effects of seizures in neonatal rats on spatial learning ability and N-methyl-D-aspartate receptor expression in the brain

  4. 鸭病毒性肠炎病毒CH强毒株适应在鸭胚成纤维细胞上生长的研究

    Institute of Scientific and Technical Information of China (English)

    郭宇飞; 程安春; 汪铭书; 贾仁勇; 文明; 周伟光; 陈孝跃

    2007-01-01

    对分离自鸭体的鸭病毒性肠炎病毒CH强毒株(DEV-CHv)进行了适应在鸭胚成纤维细胞(DEF)上生长的研究.结果表明,DEV-CHv病死鸭肝脏悬液以绒毛尿囊腔途径经10日龄鸭胚连续传代2次,取尿囊液接种细胞的方法可获得适应DEF生长的DEV-CHv,而肝组织内病毒直接接种在DEF上则不生长.DEV-CHv刚适应DEF时以细胞变圆、折光度增强为病变特征,而适应DEF后以细胞脱落和形成圆形蚀斑为特征.适应DEF的DEV-CHv通常30h左右使细胞脱落,36 h左右在细胞单层上形成蚀斑,48 h时细胞病变可达80%以上.

  5. Molecular Characterization of the Duck Enteritis Virus UL4 Gene

    Institute of Scientific and Technical Information of China (English)

    Hua-qi PAN; Nan WANG; Li LIU; Lei LIU; Jiang-chun HU; Pu-yan CHEN; Shu-jin WANG; Rui-bing CAO

    2009-01-01

    Duck enteritis virus (DEV) is a herpesvirus that causes an acute, contagious and fatal disease. In the present article, the DEV UL4 gene was cloned and sequenced from a vaccine virus. A degenerate oligonucleotide primer for the consensus site of herpesvirus UL3 gene and a specific primer located in UL5 were used in the polymerase chain reaction (PCR) to amplify a DNA product 2 086 bp in size. DNA sequence analysis revealed that a 714 bp open reading frame (ORF) of DEV encoding a 237 amino acid polypeptide is homologous to the family of herpesvirus UL4 proteins and therefore has been characterized as a DEV UL4 gene. Alignment of the DEV UL4 protein sequence with those of other alphaherpesviruses showed that 10 amino acid residues are completely conserved. Phylogenetic tree analysis showed that the seventeen alphaherpesviruses viruses analyzed were classified into four large groups, and the duck enteritis virus branched separately, closely related to the Mardiviruses group comprising Gallid herpesvirus 2 (GaHV-2), Gallid herpesvirus 3 (GaHV-3) and Meleagrid herpesvirus 1 (MeHV-1). The present study showed that the evolutionary relationship of the UL4 protein could be used for classification of alphaherpesviruses.

  6. Discrete-event modeling and simulation a practitioner's approach

    CERN Document Server

    Wainer, Gabriel A

    2009-01-01

    Complex artificial dynamic systems require advanced modeling techniques that can accommodate their asynchronous, concurrent, and highly non-linear nature. Discrete Event systems Specification (DEVS) provides a formal framework for hierarchical construction of discrete-event models in a modular manner, allowing for model re-use and reduced development time.Discrete Event Modeling and Simulation presents a practical approach focused on the creation of discrete-event applications. The book introduces the CD++ tool, an open-source framework that enables the simulation of discrete-event models. After setting up the basic theory of DEVS and Cell-DEVS, the author focuses on how to use the CD++ tool to define a variety of models in biology, physics, chemistry, and artificial systems. They also demonstrate how to map different modeling techniques, such as Finite State Machines and VHDL, to DEVS. The in-depth coverage elaborates on the creation of simulation software for DEVS models and the 3D visualization environment...

  7. Framework for automatic information extraction from research papers on nanocrystal devices

    Directory of Open Access Journals (Sweden)

    Thaer M. Dieb

    2015-09-01

    Full Text Available To support nanocrystal device development, we have been working on a computational framework to utilize information in research papers on nanocrystal devices. We developed an annotated corpus called “ NaDev” (Nanocrystal Device Development for this purpose. We also proposed an automatic information extraction system called “NaDevEx” (Nanocrystal Device Automatic Information Extraction Framework. NaDevEx aims at extracting information from research papers on nanocrystal devices using the NaDev corpus and machine-learning techniques. However, the characteristics of NaDevEx were not examined in detail. In this paper, we conduct system evaluation experiments for NaDevEx using the NaDev corpus. We discuss three main issues: system performance, compared with human annotators; the effect of paper type (synthesis or characterization on system performance; and the effects of domain knowledge features (e.g., a chemical named entity recognition system and list of names of physical quantities on system performance. We found that overall system performance was 89% in precision and 69% in recall. If we consider identification of terms that intersect with correct terms for the same information category as the correct identification, i.e., loose agreement (in many cases, we can find that appropriate head nouns such as temperature or pressure loosely match between two terms, the overall performance is 95% in precision and 74% in recall. The system performance is almost comparable with results of human annotators for information categories with rich domain knowledge information (source material. However, for other information categories, given the relatively large number of terms that exist only in one paper, recall of individual information categories is not high (39–73%; however, precision is better (75–97%. The average performance for synthesis papers is better than that for characterization papers because of the lack of training examples for

  8. Evaluation of two compounds as possible radioprotectors

    International Nuclear Information System (INIS)

    Radioprotecting effectivity of S-[2-(diethylamino)ethyl]4-methylbenzothiohydroximate hydrochloride (Dev-B-g) and S-[2-(diethylamino)ethyl]α-keto 4-methyl benzothiohydroximate hydrochloride (Dev-B 43) were evaluated by both survival studies in mice exposed to 10.5 Gy whole body γ-irradiation and 24 hours deoxycitidine (CdR) excretion in urine of rats following 5 Gy irradiation. The drugs were tested after intraperitioneal (i.p.) administration. The drugs rendered significant protection in sublethal (5 Gy) irradiation but could not protect against 10.5 Gy exposure. (orig.)

  9. Development Of Buddhistic Art And Architecture Of rd th Kashmir From 3 Century.b.C To A.D. 13 Century.

    Directory of Open Access Journals (Sweden)

    Hilal Ahmad Shah

    2013-08-01

    Full Text Available Buddhistic art and architecture seems to have obtained a footing in Kashmir valley, during the 3 century rd th B.C. From 3 century B.C to 13 century A.D. Kashmir was ruled by the rulers of Mauryan, Kushan, Gonanda, Hun, Karkota, Utpala, Lohara and Dev dynasties, except the rulers of Huna and Dev dynasties, the Buddhistic art and architecture of Kashmir got liberal patronage from time to time. Many rulers of Mauryan, Kushan, Gananda, Karkota, Utpala and Lohara dynasties built many Viharas, Mathas, Chaityas, Stupas, Scluptures of Lord Buddha and Bodhisatvas and similar other structures.

  10. Le développement des nāyikābhedas de la littérature sanskrite à la littérature braj : la naissance d'un genre

    OpenAIRE

    Cattoni Nadia

    2014-01-01

    This article has as its aim to follow the development of a sub-genre called nāyikābheda s through the kāmaśātra s and alaṅkāraśāstra s of Sanskrit literature, Bhānudatta's Rasamañjarī , vernacular literature and the example of the Braj author Dev. Drawing on a few examples from the works of Dev, a skilled poet concerning the descriptions of the nāyikā s, we will see from where the poet takes his inspiration, how he transgresses...

  11. Le développement des nāyikābhedas de la littérature sanskrite à la littérature braj: la naissance d’un genre

    OpenAIRE

    Cattoni, Nadia

    2014-01-01

    This article has as its aim to follow the development of a sub-genre called nāyikābhedas through the kāmaśātras and alaṅkāraśāstras of Sanskrit literature, Bhānudatta’s Rasamañjarī , vernacular literature and the example of the Braj author Dev. Drawing on a few examples from the works of Dev, a skilled poet concerning the descriptions of the nāyikās, we will see from where the poet takes his inspiration, how he transgresses genre boundaries and the way he creates typologies ...

  12. Adaptive Task Size Control on High Level Programming for GPU/CPU Work Sharing

    OpenAIRE

    Odajima, Tetsuya; Boku, Taisuke; Sato, Mitsuhisa; Hanawa, Toshihiro; Kodama, Yuetsu; Namyst, Raymond; Thibault, Samuel; Aumage, Olivier

    2013-01-01

    On the work sharing among GPUs and CPU cores on GPU equipped clusters, it is a critical issue to keep load balance among these heterogeneous computing resources. We have been developing a runtime system for this problem on PGAS language named XcalableMP- dev/StarPU [1]. Through the development, we found the necessity of adaptive load balancing for GPU/CPU work sharing to achieve the best performance for various application codes. In this paper, we enhance our language system XcalableMP-dev/St...

  13. Expression and characterization of the UL31 protein from duck enteritis virus

    Directory of Open Access Journals (Sweden)

    Zhu Dekang

    2009-02-01

    Full Text Available Abstract Background Previous studies indicate that the UL31 protein and its homology play similar roles in nuclear egress of all herpesviruses. However, there is no report on the UL31 gene product of DEV. In this study, we expressed and presented the basic properties of the DEV UL31 product. Results The entire ORF of the UL31 was cloned into pET 32a (+ prokaryotic expression vector. Escherichia coli BL21(DE3 competent cells were transformed with the construct followed by the induction of protein expression by the addition of IPTG. Band corresponding to the predicted sizes (55 kDa was produced on the SDS-PAGE. Over expressed 6×His-UL31 fusion protein was purified by nickel affinity chromatography. The DEV UL31 gene product has been identified by using a rabbit polyclonal antiserum raised against the purified protein. A protein of approximate 35 kDa that reacted with the antiserum was detected in immunoblots of DEV-infected cellular lysates, suggesting that the 35 kDa protein was the primary translation product of the UL31 gene. RT-PCR analyses revealed that the UL31 gene was transcribed most abundantly during the late phase of replication. Subsequently, Immunofluorescence analysis revealed that the protein was widespread speckled structures in the nuclei of infected cells. Western blotting of purified virion preparations showed that UL31 was a component of intracellular virions but was absent from mature extracellular virions. Finally, an Immunofluorescence assay was established to study the distribution of the UL31 antigen in tissues of artificially DEV infected ducks. The results showed that the UL31 antigen was primarily located in the cells of digestive organs and immunological organs. Conclusion In this work, we present the basic properties of the DEV UL31 product. The results indicate that DEV UL31 shares many similarities with its HSV or PRV homolog UL31 and suggest that functional cross-complementation is possible between members of the

  14. Depression and Anxiety in Iranian Mothers of Children with Epilepsy

    Directory of Open Access Journals (Sweden)

    Atefeh SOLTANIFAR

    2012-03-01

    JS, Lisonkova S. Periodprevalence of epilepsy in children in BC: a population-basedstudy. Can J Neurol Sci 2009 Jan;36(1:36-41.3. Otero S. Psychopathology and psychological adjustmentin children and adolescents with epilepsy. World J Pediatr2009 Feb;5(1:12-7.4. Rodenburg HR, Stams GJJM, Meijer AM, Aldenkamp AP,Dekovic´ M. Psychopathology in children with epilepsy:a metaanalysis. J Pediatr Psychol 2005 Sep;30(6:453-68.Epub 2005 Mar 3.5. Rodenburg R, Meijer AM, Dekovic M, AldenkampAP. Family factors and psychopathology in childrenwith epilepsy: a literature review. Epilepsy Behav 2005Jun;6(4:488-503.6. Lovejoy M, Graczyk PA, O_Hare E, Neuman G. Maternaldepression and parenting behavior: a meta-analytic reviewClin Psychol Rev 2000;20:561-92.7. Shore CP, Buelow JM, Austin JK, Johnson CS.Continuing psychosocial care needs in children with newonsetepilepsy and their parents. J Neurosci Nurs 2009Oct;41(5:244-50.8. Pianta RC, Lothman DJ. Predicting behavior problemsin children with epilepsy: child factors, disease factors,family stress, and child-mother interaction. Child Dev1994 Oct;65(5:1415-28.9. Dunn DW, Austin JK, Huster GA. Symptoms ofdepression in adolescents with epilepsy. J Am Acad ChildAdolesc Psychiatr 1999;38:1133-8.10. Shore CP, Austin JK, Huster GA, Dunn DW. Identifyingrisk factors for maternal depression in families ofadolescents with epilepsy. J Specialists Pediatr Nurs2002;7:71-80.11. Yongli, Cheng-Ye ji, Jiong Qin, Zhi-Xiang Zhang.Parental anxiety and quality of Life of epileptic children.Biomed Environ Sci 2008 Jun;21(3:228-32.12. Williams J, Steel C, Sharp GB, DelosReyes E, PhillipsT, Bates S, et al. Parental anxiety and quality of life inchildren with epilepsy. Epilepsy Behav 2003;4:483-6.13. Lv R, Wu L, Jin L, Lu Q, Wang M, Qu Y, Liu H. Depression,anxiety and quality of life in parents of children withepilepsy. Acta Neurol Scand 2009 Nov;120(5:335-41.14. Baki O, Erdogan A, Kantarci O, Akisik G, KayaalpL, Yalcinkaya C. Anxiety and depression in

  15. Efficacy and Safety of Intravenous Sodium Valproate in Convulsive Status Epilepticus in Children in Shahid Sadoughi Hospital

    Directory of Open Access Journals (Sweden)

    Razieh FALLAH

    2012-06-01

    Full Text Available How to Cite this Article: Fallah R, Yadegari Y, Salmani Nodushan M. Efficacy and Safety of Intravenous Sodium Valproate in Convulsive Status Epilepticus in Children in Shahid Sadoughi Hospital. Iran. J. Child. Neurol 2012;6(2:39-44. Objective Status epilepticus (SE is the most common pediatric neurologic emergency with high mortality and morbidity. There is no consensus on the drug of choice in the treatment of children. The purpose of this study was to evaluate the clinical efficacy and safety of intravenous sodium valproate as a third-line drug in the treatment of generalized convulsive SE of children. Materials & Methods In a retrospective study, medical records of those children who were admitted to Shahid Sadoughi Hospital of Yazd due to refractory generalized convulsive SE and were treated by intravenous sodium valproate as a third-line drug from 2009 to 2011 were evaluated. Results Six girls and five boys with a mean age of 5.12 ± 1.2 years (range: 3 - 9.6 years were evaluated. Intravenous valproate was effective for cessation of seizures in seven patients (63.6 %. The mean dose of valproate for stopping seizures was 27.1 ± 1.4 mg/kg/day. Children whose seizures were controlled by sodium valproate were older than non- responsive children (mean± SD: 4.8 ± 1.2 years vs. 3.1 ± 0.43 years, p= 0.03 and they also had shorter ICU stay days (mean± SD: 2.6 ± 1.4 days vs. 5.6 ± 2.8 days, p= 0.01. Two children had mild and transient nausea and vomiting. None of them had cardiopulmonary or severe paraclinical side effects. Conclusion Intravenous sodium valproate may be used as an effective and safe third-line antiepileptic drug in the treatment of pediatric generalized convulsive status epilepticus.References Raj D, Gulati S, Lodha R. Status epilepticus. Indian J Pediatr 2011;78(2:219-26. Shearer P, Riviello J. Generalized convulsive status epilepticus in adults and children: treatment guidelines and protocols. Emerg Med Clin North Am 2011

  16. Animal, animalité, devenir-animal

    OpenAIRE

    Viennet, Denis

    2011-01-01

    Question de regard Nous regardons les animaux et les animaux nous regardent. Nous faisons signe à un chat, par la voix, par le geste, le chat nous regarde et cligne des yeux. Il n’a pas la capacité d’exprimer des paroles selon le modèle humain, mais à sa manière il nous répond, par un clin d’œil. Que se passe-t-il dans ce clin d’œil ? Une communication s’établit, un échange a lieu. Nous regardons l’animal qui nous regarde. Que voyons-nous alors ? Le clin d’œil énigmatique nous pousse à regard...

  17. EXPRESSION OF EPIDERMAL GROWTH FACTOR, TRANSFORMING GROWTH FACTOR-a AND THEIR RECEPTOR IN HUMAN PITUITARY TUMORS

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Long

    2001-01-01

    [1]LIU Xu-wen, FU Pei-yu, GAO Zhi-xian. Expression of epidermal growth factor receptors in human glioma [J]. Chin J Neurosurgery 1998; 14:71.[2]Wong AJ, Ruppert JM, Bigner SH, et al. Structural alterations of the epidermal growth factor receptor gene in human gliomas [J]. Proc Natl Acad Sci USA 1992; 89:4309.[3]Webster J, Ham J, Bevan JS. Preliminary characterization of growth factors secreted by human pituitary tumors [J]. J Clin Endocrinol Metab 1991; 72:687.[4]Klibanski A. Nonsecreting pituitary tumors [J]. Endocrinol Metab Clin North Am 1987; 16:793.[5]LeRiche VK, Asa SL, Ezzat S. Epidermal growth factor and its receptor (EGF-R) in human pituitary adenomas: EGF-R correlates with tumor aggressiveness [J]. J Clin Endocrinol Metab 1996; 81:656.

  18. Survey of ICT and Education in Africa : Equatorial Guinea Country Report

    OpenAIRE

    Fall, Babacar

    2007-01-01

    This short country report, a result of a larger Information for Development Program (infoDev)-supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. In Equatorial Guinea, there is no specific policy concerning ICT, although attempts to impro...

  19. Survey of ICT and Education in Africa : Liberia Country Report

    OpenAIRE

    Mangesi, Kofi

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Liberia is in the process of developing a comprehensive ICT policy called E-Liberia: vision ...

  20. Survey of ICT and Education in Africa : Uganda Country Report

    OpenAIRE

    Farrell, Glen

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. As it adopts ICT in education, Uganda faces the same challenges as most developing economies -...

  1. Survey of ICT and Education in Africa : Lesotho Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Despite its poor ICT infrastructure and high levels of poverty, Lesotho has begun to take th...

  2. Survey of ICT and Education in Africa : Swaziland Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Swaziland is a small, deeply impoverished, drought-stricken country with a weak ICT infrastruc...

  3. Survey of ICT and Education in Africa : Seychelles Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Seychelles is considered as one of the richest countries in Africa by income per capita. The...

  4. Survey of ICT and Education in Africa : Tanzania Country Report

    OpenAIRE

    Hare, Harry

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The past few years witnessed a host of activities aimed at injecting ICT in Tanzania's educati...

  5. Survey of ICT and Education in Africa : Rwanda Country Report

    OpenAIRE

    Farrell, Glen

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. ICT is central to Rwanda's Vision for 2020, and ICT in education is one of the core pillars ...

  6. Survey of ICT and Education in Africa : Sierra Leone Country Report

    OpenAIRE

    Mangesi, Kofi

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. As a country recovering from a devastating civil war that destroyed its infrastructure, Sier...

  7. Survey of ICT and Education in Africa : Djibouti Country Report

    OpenAIRE

    Hare, Harry

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Djibouti boasting a digital telecommunications network and connections to the rest of the wo...

  8. Survey of ICT and Education in Africa : Madagascar Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Madagascar has begun to take steps towards promoting ICTs for development with the adoption of two...

  9. Survey of ICT and Education in Africa : Senegal Country Report

    OpenAIRE

    Fall, Babacar

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Senegal's hand on commitment to incorporating ICT in education is still in the beginning sta...

  10. Survey of ICT and Education in Africa : Burundi Country Report

    OpenAIRE

    Hare, Harry

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The crisis of 1993 and the long drawn-out conflict that followed in Burundi had a devastating effe...

  11. Language functions in preterm-born children: A systematic review and meta-analysis

    NARCIS (Netherlands)

    I.L. Van Noort-van Der Spek (Inge); M-C. Franken (Marie-Christine); N. Weisglas-Kuperus (Nynke)

    2012-01-01

    textabstractBACKGROUND AND OBJECTIVE: Preterm-born children (dev

  12. CERN Computing Colloquia Spring Series: IT Security - A High-Performance Pattern Matching Engine for Intrusion Detection

    CERN Document Server

    CERN. Geneva

    2006-01-01

    The flexible and modular design of the engine allows a broad spectrum of applications, ranging from high-end enterprise level network devices that need to match hundreds of thousands of patterns at speeds of tens of gigabits per second, to low-end dev...

  13. DMPD: Pathways connecting inflammation and cancer. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 18325755 Pathways connecting inflammation and cancer. Allavena P, Garlanda C, Borre...llo MG, Sica A, Mantovani A. Curr Opin Genet Dev. 2008 Feb;18(1):3-10. Epub 2008 Mar 5. (.png) (.svg) (.html) (.csml) Show Pathways... connecting inflammation and cancer. PubmedID 18325755 Title Pathways connecting infl

  14. Improving adolescent sexual and reproductive health in Latin America: reflections from an International Congress

    NARCIS (Netherlands)

    K. Córdova Pozo; V. Chandra-Mouli; P. Decat; E. Nelson; S. de Meyer; L. Jaruseviciene; B. Vega; Z. Segura; N. Auquilla; A. Hagens; D. van Braeckel; K. Michielsen

    2015-01-01

    In February 2014, an international congress on Promoting Adolescent Sexual and Reproductive Health (ASRH) took place in Cuenca, Ecuador. Its objective was to share evidence on effective ASRH intervention projects and programs in Latin America, and to link this evidence to ASRH policy and program dev

  15. Village Sanitation and Children's Human Capital: Evidence from a Randomized Experiment by the Maharashtra Government

    OpenAIRE

    Hammer, Jeffrey; Spears, Dean

    2013-01-01

    Open defecation is exceptionally widespread in India, a county with puzzlingly high rates of child stunting. This paper reports a randomized controlled trial of a village-level sanitation program, implemented in one district by the government of Maharashtra. The program caused a large but plausible average increase in child height (95 percent confidence interval [0.04 to 0.61] standard dev...

  16. Survey of ICT and Education in Africa : Chad Country Report

    OpenAIRE

    Fall, Babacar

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Chad and its partners in development have adopted a 10-year strategy called Education and Training...

  17. Survey of ICT and Education in Africa : Egypt Country Report

    OpenAIRE

    Hamdy, Amr

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Egypt faces significant challenges in harnessing its education system to promote its development p...

  18. Survey of ICT and Education in Africa : Morocco Country Report

    OpenAIRE

    Hamdy, Amr

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The Moroccan government has realized the key role played by ICT-based education as a positiv...

  19. Survey of ICT and Education in Africa : Comoros Country Report

    OpenAIRE

    Ngombo, Florence; Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Comoros - one of the poorest and smallest countries in the world, with a coup-prone, turbule...

  20. Parents' Translations of Child Gesture Facilitate Word Learning in Children with Autism, Down Syndrome and Typical Development

    Science.gov (United States)

    Dimitrova, Nevena; Özçaliskan, Seyda; Adamson, Lauren B.

    2016-01-01

    Typically-developing (TD) children frequently refer to objects uniquely in gesture. Parents translate these gestures into words, facilitating children's acquisition of these words (Goldin-Meadow et al. in "Dev Sci" 10(6):778-785, 2007). We ask whether this pattern holds for children with autism (AU) and with Down syndrome (DS) who show…

  1. Does Financial Development Increase Energy Consumption? Role of Industrialization and Urbanization in Tunisia

    OpenAIRE

    Muhammad, Shahbaz; Lean, Hooi Hooi

    2011-01-01

    This paper assesses the relationship among energy consumption, financial development, economic growth, industrialization and urbanization in Tunisia from 1971-2008. The autoregressive distributed lag bounds testing approach to cointegration and Granger causality tests are employed for the analysis. The result confirms the existence of long-run relationship between energy consumption, economic growth, financial development, industrialization and urbanization in Tunisia. Moreover, financial dev...

  2. 77 FR 285 - Notice of Proposals To Engage in or To Acquire Companies Engaged in Permissible Nonbanking...

    Science.gov (United States)

    2012-01-04

    ... From the Federal Register Online via the Government Publishing Office FEDERAL RESERVE SYSTEM... Regulation Y (12 CFR 225.28) or that the Board has determined by Order to be closely related to banking and... Reserve System, December 28, 2011. Robert deV. Frierson, Deputy Secretary of the Board. BILLING CODE...

  3. 75 FR 2544 - Notice of Proposals to Engage in Permissible Nonbanking Activities or to Acquire Companies that...

    Science.gov (United States)

    2010-01-15

    ... From the Federal Register Online via the Government Publishing Office FEDERAL RESERVE SYSTEM... determined by Order to be closely related to banking and permissible for bank holding companies. Unless... Regulation Y. Board of Governors of the Federal Reserve System, January 11, 2010. Robert deV....

  4. 77 FR 39494 - Notice of Proposals To Engage in or To Acquire Companies Engaged in Permissible Nonbanking...

    Science.gov (United States)

    2012-07-03

    ... From the Federal Register Online via the Government Publishing Office FEDERAL RESERVE SYSTEM... Regulation Y (12 CFR 225.28) or that the Board has determined by Order to be closely related to banking and... System, June 28, 2012. Robert deV. Frierson, Deputy Secretary of the Board. BILLING CODE 6210-01-P...

  5. Y2K action at the World Bank. The millennium bug and development

    International Nuclear Information System (INIS)

    The initiative of World Bank's 'infoDev programme' addresses developing countries to devise contingency plans for those vital systems that are not yet Y2K (year 2000) ready. It continues to support actions in helping countries better assess their status of readiness, and deal with regional and global interfaces

  6. 76 FR 70722 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

    Science.gov (United States)

    2011-11-15

    ... From the Federal Register Online via the Government Publishing Office FEDERAL RESERVE SYSTEM... Banking Corporation, both of Tokyo, Japan, to increase their ownership interest to 9.9 percent of the... of the Federal Reserve System, November 9, 2011. Robert deV. Frierson, Deputy Secretary of the...

  7. 77 FR 1072 - Notice of Proposals To Engage in or To Acquire Companies Engaged in Permissible Nonbanking...

    Science.gov (United States)

    2012-01-09

    ... From the Federal Register Online via the Government Publishing Office FEDERAL RESERVE SYSTEM... Regulation Y (12 CFR 225.28) or that the Board has determined by Order to be closely related to banking and... System, January 4, 2012. Robert deV. Frierson, Deputy Secretary of the Board. BILLING CODE 6210-01-P...

  8. 76 FR 75549 - Notice of Proposals To Engage in or To Acquire Companies Engaged in Permissible Nonbanking...

    Science.gov (United States)

    2011-12-02

    ... From the Federal Register Online via the Government Publishing Office FEDERAL RESERVE SYSTEM... Regulation Y (12 CFR 225.28) or that the Board has determined by Order to be closely related to banking and... Reserve System, November 28, 2011. Robert deV. Frierson, Deputy Secretary of the Board. BILLING CODE...

  9. A New GIS-Nitrogen Trading Tool Concept to Minimize Reactive Nitrogen losses to the Environment

    Science.gov (United States)

    Nitrogen (N) is an essential element which is needed to maximize agricultural production and sustainability of worldwide agroecosystems. N losses to the environment are impacting water and air quality that has become an environmental concern for the future generations. It has led to the need for dev...

  10. Measuring correlated electronic and vibrational spectral dynamics using line shapes in two-dimensional electronic-vibrational spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, Nicholas H. C.; Dong, Hui; Oliver, Thomas A. A.; Fleming, Graham R., E-mail: grfleming@lbl.gov [Department of Chemistry, University of California, Berkeley, California 94720 (United States); Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Kavli Energy NanoSciences Institute at Berkeley, Berkeley, California 94720 (United States)

    2015-05-07

    Two-dimensional electronic-vibrational (2DEV) spectroscopy is an experimental technique that shows great promise in its ability to provide detailed information concerning the interactions between the electronic and vibrational degrees of freedom in molecular systems. The physical quantities 2DEV is particularly suited for measuring have not yet been fully determined, nor how these effects manifest in the spectra. In this work, we investigate the use of the center line slope of a peak in a 2DEV spectrum as a measure of both the dynamic and static correlations between the electronic and vibrational states of a dye molecule in solution. We show how this center line slope is directly related to the solvation correlation function for the vibrational degrees of freedom. We also demonstrate how the strength with which the vibration on the electronic excited state couples to its bath can be extracted from a set of 2DEV spectra. These analytical techniques are then applied to experimental data from the laser dye 3,3′-diethylthiatricarbocyanine iodide in deuterated chloroform, where we determine the lifetime of the correlation between the electronic transition frequency and the transition frequency for the backbone C = C stretch mode to be ∼1.7 ps. Furthermore, we find that on the electronic excited state, this mode couples to the bath ∼1.5 times more strongly than on the electronic ground state.

  11. Disease: H00841 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ated with sensorineural deafness. The same clinical presentation without deafness is also known as Fazio Lon...ou A, Vagiakou EA Infantile progressive bulbar palsy with deafness. Brain Dev 24:732-5 (2002) PMID:21110228 ...n Laere syndrome (BVVLS) is characterized by progressive pontobulbar palsy associ

  12. Cell lines and Salmonella

    NARCIS (Netherlands)

    Jonge R de; Hendriks H; Garssen J; Universteit Utrecht, afdeling; MGB; LPI

    2001-01-01

    In human gastrointestinal disease caused by Salmonella, transepithelial migration of neutrophils follows the attachment of bacteria to epithelial tissue. This migration of neutrophils is stimulated by the release of chemokines, including interleukin-8 (Il -8), from the epithelial cells. We have dev

  13. Self-Perceived Stability and Change in Children's Competence

    Science.gov (United States)

    Vandenplas-Holper, Christiane; Roskam, Isabelle; Fontaine, Anne-Marie

    2010-01-01

    Using Harter's ("Child Dev" 53(1):87-97, 1982) perceived competence scale, this study integrates several paradigms related to the issues of self-perceived competence, stability or change and attributional theory. It examines how 268 Belgian and Portuguese fifth graders consider their scholastic, social and physical competence at present and in a…

  14. Environmental risk assessment of veterinary medicines used in Asian aquaculture

    NARCIS (Netherlands)

    Rico, A.

    2014-01-01

      One of the major constraints for the development and expansion of the Asian aquaculture industry has been the proliferation of disease outbreaks. To overcome this issue, a wide range of veterinary medicines including antibiotics, parasiticides and medical disinfectants have been recently dev

  15. Sensory analysis of rainbow trout, oncorhynchus mykiss, fed enriched black soldier fly prepupae, hermetia illucens

    Science.gov (United States)

    A growth trial and fillet sensory analysis were conducted to examine the effects of replacing dietary fish meal with black soldier fly (BSF) prepupae, Hermetia illucens, in rainbow trout, Oncorhynchus mykiss. A practical-type trout diet was formulated to contain 45% protein; four test diets were dev...

  16. Evaluation of 1066 ToxCast Chemicals in a human stem cell assay for developmental toxicity (SOT)

    Science.gov (United States)

    To increase the diversity of assays used to assess potential developmental toxicity, the ToxCast chemical library was screened in the Stemina devTOX quickPREDICT assay using human embryonic stem (hES) cells. A model for predicting teratogenicity was based on a training set of 23 ...

  17. Development of C++ Application Program for Solving Quadratic Equation in Elementary School in Nigeria

    Science.gov (United States)

    Bandele, Samuel Oye; Adekunle, Adeyemi Suraju

    2015-01-01

    The study was conducted to design, develop and test a c++ application program CAP-QUAD for solving quadratic equation in elementary school in Nigeria. The package was developed in c++ using object-oriented programming language, other computer program that were also utilized during the development process is DevC++ compiler, it was used for…

  18. Total performances scorecard and the sustainable development of the organizational and personal performances

    OpenAIRE

    Amalia Venera TODORUŢ

    2010-01-01

    In this paper I wanted to approach the relationship between Total Performances Scorecard and other concepts related to the continuous improvement, namely: Total Quality Management, Balanced Scorecard, Performance Management and Skills Management. Total Performances Scorecard is a holistic concept of improvement and change management. In the TPS concept, improvement, development and learning are treated as cyclic and ethical processes, through which the dev...

  19. Education and research at clean room laboratory for silicon device technology at Masaryk University

    Czech Academy of Sciences Publication Activity Database

    Mikulík, P.; Humlíček, J.; Hovorka, Miloš; Kulha, P.; Kadlec, F.

    Praha: IOP AS CR, 2012 - (Fejfar, A.; Vetushka, A.) ISBN 978-80-260-0619-0. [Physics at Nanoscale. IUVSTA International Summer School /10./. Devět skal (CZ), 30.05.2012-04.06.2012] Institutional support: RVO:68081731 Keywords : silicon device technology * education and research * clean room laboratory Subject RIV: BH - Optics, Masers, Lasers

  20. A Feminist Political Economic Analysis of the US Chicken Industry

    OpenAIRE

    Kristin Sampson

    2008-01-01

    Kristin Sampson gives an overview of competing poultry production systems from a feminist political economic analysis. She considers three characteristics of the US industry, identified as key drivers of the industry's success: structural organization, production and processing technologies and responsiveness to consumer demands. Development (2008) 51, 547–554. doi:10.1057/dev.2008.59

  1. The European Romani Women's Movement: The struggle for human rights

    OpenAIRE

    Rita Izsák

    2009-01-01

    Rita Izsák discusses the International Romani Women's Network (IRWN), the first registered international umbrella organization representing Romani women of all European Romani groups. She examines how IRWN is promoting women's rights, and the connection between mainstream feminist movements and the Romani movement. Development (2009) 52, 200–207. doi:10.1057/dev.2009.9

  2. How to Manufacture a Global Food Crisis

    OpenAIRE

    Walden Bello

    2008-01-01

    Reviewing the policies of the World Bank, the International Monetary Fund and the World Trade Organization, Walden Bello examines how ‘free trade’ is destroying Third World agriculture – and who's fighting back. Development (2008) 51, 450–455. doi:10.1057/dev.2008.60

  3. Measuring correlated electronic and vibrational spectral dynamics using line shapes in two-dimensional electronic-vibrational spectroscopy.

    Science.gov (United States)

    Lewis, Nicholas H C; Dong, Hui; Oliver, Thomas A A; Fleming, Graham R

    2015-05-01

    Two-dimensional electronic-vibrational (2DEV) spectroscopy is an experimental technique that shows great promise in its ability to provide detailed information concerning the interactions between the electronic and vibrational degrees of freedom in molecular systems. The physical quantities 2DEV is particularly suited for measuring have not yet been fully determined, nor how these effects manifest in the spectra. In this work, we investigate the use of the center line slope of a peak in a 2DEV spectrum as a measure of both the dynamic and static correlations between the electronic and vibrational states of a dye molecule in solution. We show how this center line slope is directly related to the solvation correlation function for the vibrational degrees of freedom. We also demonstrate how the strength with which the vibration on the electronic excited state couples to its bath can be extracted from a set of 2DEV spectra. These analytical techniques are then applied to experimental data from the laser dye 3,3'-diethylthiatricarbocyanine iodide in deuterated chloroform, where we determine the lifetime of the correlation between the electronic transition frequency and the transition frequency for the backbone C = C stretch mode to be ∼1.7 ps. Furthermore, we find that on the electronic excited state, this mode couples to the bath ∼1.5 times more strongly than on the electronic ground state. PMID:25956093

  4. Imaging of SiCN thin films on silicon substrate in the scanning low energy electron microscope

    Czech Academy of Sciences Publication Activity Database

    Zobačová, Jitka; Hüger, E.; Urbánek, Michal; Polčák, J.; Frank, Luděk

    Praha : IOP AS CR, 2012 - (Fejfar, A.; Vetushka, A.) ISBN 978-80-260-0619-0. [ Physic s at Nanoscale. IUVSTA International Summer School /10./. Devět skal (CZ), 30.05.2012-04.06.2012] Institutional support: RVO:68081731 Keywords : SiCN thin films * sillicon substrate * scanning low energy electron microscope Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

  5. Mapping of dopants in silicon by electron injection

    Czech Academy of Sciences Publication Activity Database

    Hovorka, Miloš; Konvalina, Ivo; Frank, Luděk; Mikulík, P.

    Praha : IOP AS CR, 2012 - (Fejfar, A.; Vetushka, A.) ISBN 978-80-260-0619-0. [ Physic s at Nanoscale. IUVSTA International Summer School /10./. Devět skal (CZ), 30.05.2012-04.06.2012] Institutional support: RVO:68081731 Keywords : mapping of dopants in sillicon * electron injection Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

  6. Reference: P1BS [PLACE

    Lifescience Database Archive (English)

    Full Text Available P1BS Rubio V, Linhares F, Solano R, Martin AC, Iglesias J, Leyva A, Paz-Ares J. A conserved MYB ... gnaling both in vascular plants and in unicellular algae . Genes Dev. 15: 2122-2133.(2001) PubMed: 11511543 ...

  7. Asymmetry and infants born preterm

    NARCIS (Netherlands)

    Nuijsink, J.

    2012-01-01

    The main aim of the thesis was to contribute to the diagnostic process and clinical decision making by pediatric physiotherapists in very young infants with an atypical motor performance, influenced by both an asymmetric development, and a development according to a preterm birth. In Part I, the dev

  8. Handshake, No. 5 (April 2012)

    OpenAIRE

    International Finance Corporation

    2012-01-01

    This issue includes the following headings: seeds and soil: smallholder agriculture; innovation: pairing commercial buyers with rural producers; grain storage: a ready role for public-private partnerships (PPPs); agricultural clusters: powering Africas agricultural potential; and interviews: AgDevCo, bill and Melinda gates foundation, earth policy institute.

  9. Developing Linux kernel space device driver

    Institute of Scientific and Technical Information of China (English)

    Zheng Wei; Wang Qinruo; Wu Naiyou

    2003-01-01

    This thesis introduces how to develop kernel level device drivers on Linux platform in detail. On the basis of comparing proc file system with dev file system, we choose PCI devices and USB devices as instances to introduce the method of writing device drivers for character devices by using these two file systems.

  10. Metamorphic history of the Central Pyrenees Part II, Valle de Arán, Sheet 4

    NARCIS (Netherlands)

    Zwart, H.J.

    1963-01-01

    The structural geology and metamorphic petrology of the Bosost area in the Valle de Arán (Central Pyrenees) is discussed. The rocks exposed in this area consist of Cambro-Ordovician mica-schists with numerous granite and pegmatite bodies, phyllites and limestones; Silurian slates and schists and Dev

  11. Main: 1QNE [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1QNE シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. Tata-Box Binding Protein 1 Name ... Box-Binding Protein Has Been Conserved Throughout Evolution ... Genes Dev. V. 13 3217 1999 Tata Box-Binding Protei ...

  12. Main: 1QN7 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1QN7 シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. Tata-Box Binding Protein 1 Name ... Box-Binding Protein Has Been Conserved Throughout Evolution ... Genes Dev. V. 13 3217 1999 Tata Box-Binding Protei ...

  13. Main: 1QN3 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1QN3 シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. Tata-Box Binding Protein 1 Name ... Box-Binding Protein Has Been Conserved Throughout Evolution ... Genes Dev. V. 13 3217 1999 Tata Box-Binding Protei ...

  14. Main: 1QN8 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1QN8 シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. Tata-Box Binding Protein 1 Name ... Box-Binding Protein Has Been Conserved Throughout Evolution ... Genes Dev. V. 13 3217 1999 Tata Box-Binding Protei ...

  15. Main: 1QN9 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1QN9 シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. Tata-Box Binding Protein 1 Name ... Box-Binding Protein Has Been Conserved Throughout Evolution ... Genes Dev. V. 13 3217 1999 Tata Box-Binding Protei ...

  16. Main: 1QN5 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1QN5 シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. Tata-Box Binding Protein 1 Name ... Box-Binding Protein Has Been Conserved Throughout Evolution ... Genes Dev. V. 13 3217 1999 Tata Box-Binding Protei ...

  17. Main: 1QN4 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1QN4 シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. Tata-Box Binding Protein 1 Name ... Box-Binding Protein Has Been Conserved Throughout Evolution ... Genes Dev. V. 13 3217 1999 Tata Box-Binding Protei ...

  18. Main: 1QNB [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1QNB シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. Tata-Box Binding Protein 1 Name ... Box-Binding Protein Has Been Conserved Throughout Evolution ... Genes Dev. V. 13 3217 1999 Tata Box-Binding Protei ...

  19. Measuring Meaningful Outcomes in Consequential Contexts: Searching for a Happy Medium in Educational Technology Research (Phase II)

    Science.gov (United States)

    Ross, Steven M.; Morrison, Jennifer R.

    2014-01-01

    In a paper published 25 years ago, Ross and Morrison ("Educ Technol Res Dev" 37(1):19-33, 1989) called for a "happy medium" in educational technology research, to be achieved by balancing high rigor of studies (internal validity) with relevance to real-world applications (external validity). In this paper, we argue that,…

  20. Survey of ICT and Education in Africa : Ethiopia Country Report

    OpenAIRE

    World Bank

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Leapfrogging is the word most technical people would use to describe the advancement, at least in ...

  1. Plate Tearing by a Cone

    DEFF Research Database (Denmark)

    Simonsen, Bo Cerup

    1998-01-01

    The present paper is concerned with steady-state plate tearing by a cone. This is a scenario where a cone is forced through a ductile metal plate with a constant lateral tip penetration in a motion in the plane of the plate. The considered process could be an idealisation of the damage, which dev...

  2. Disease: H00112 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00112 Paratyphoid fever Paratyphoid fever is a systemic febrile illness endemic in developing...eloping countries where sanitation is lacking and the access to clean water is redu... countries that is a similar to typhoid fever but gives a milder infection. The disease mainly affects those living in dev

  3. Performance Measurement in Property Management

    OpenAIRE

    Aho, Johannes

    2016-01-01

    This research examines the performance measurement of processes in property management and maintenance context. The purpose was to first, develop a framework which divides processes into modes of operation that share managerial similarities. Second, apply this framework in property management performance measurement. Constructive approach was used as the scientific research approach. An extensive literature review was first conducted after which the framework was dev...

  4. Autism Diagnostic Interview-Revised (ADI-R) Algorithms for Toddlers and Young Preschoolers : Application in a Non-US Sample of 1,104 Children

    NARCIS (Netherlands)

    de Bildt, Annelies; Sytema, Sjoerd; Zander, Eric; Bölte, Sven; Sturm, Harald; Yirmiya, Nurit; Yaari, Maya; Charman, Tony; Salomone, Erica; LeCouteur, Ann; Green, Jonathan; Bedia, Ricardo Canal; Primo, Patricia García; van Daalen, Emma; de Jonge, Maretha V.; Guðmundsdóttir, Emilía; Jóhannsdóttir, Sigurrós; Raleva, Marija; Boskovska, Meri; Rogé, Bernadette; Baduel, Sophie; Moilanen, Irma; Yliherva, Anneli; Buitelaar, Jan; Oosterling, Iris J.

    2015-01-01

    The current study aimed to investigate the Autism Diagnostic Interview-Revised (ADI-R) algorithms for toddlers and young preschoolers (Kim and Lord, J Autism Dev Disord 42(1):82–93, 2012) in a non-US sample from ten sites in nine countries (n = 1,104). The construct validity indicated a good fit of

  5. Autism Diagnostic Interview-Revised (ADI-R) Algorithms for Toddlers and Young Preschoolers: Application in a Non-US Sample of 1,104 Children

    NARCIS (Netherlands)

    Bildt, A. de; Sytema, S.; Zander, E.; Bolte, S.; Sturm, H.; Yirmiya, N.; Yaari, M.; Charman, T.; Salomone, E.; LeCouteur, A.; Green, J.; Bedia, R.C.; Primo, P.G.; Daalen, E. van; Jonge, M.V. de; Guethmundsdottir, E.; Johannsdottir, S.; Raleva, M.; Boskovska, M.; Roge, B.; Baduel, S.; Moilanen, I.; Yliherva, A.; Buitelaar, J.; Oosterling, I.J.

    2015-01-01

    The current study aimed to investigate the Autism Diagnostic Interview-Revised (ADI-R) algorithms for toddlers and young preschoolers (Kim and Lord, J Autism Dev Disord 42(1):82-93, 2012) in a non-US sample from ten sites in nine countries (n = 1,104). The construct validity indicated a good fit of

  6. Autism Diagnostic Interview-Revised (ADI-R) Algorithms for Toddlers and Young Preschoolers : Application in a Non-US Sample of 1,104 Children

    NARCIS (Netherlands)

    de Bildt, Annelies; Sytema, Sjoerd; Zander, Eric; Bolte, Sven; Sturm, Harald; Yirmiya, Nurit; Yaari, Maya; Charman, Tony; Salomone, Erica; LeCouteur, Ann; Green, Jonathan; Canal Bedia, Ricardo; Primo, Patricia Garcia; van Daalen, Emma; de Jonge, Maretha V.; Gudmundsdottir, Emilia; Johannsdottir, Sigurros; Raleva, Marija; Boskovska, Meri; Roge, Bernadette; Baduel, Sophie; Moilanen, Irma; Yliherva, Anneli; Buitelaar, Jan; Oosterling, Iris J.

    2015-01-01

    The current study aimed to investigate the Autism Diagnostic Interview-Revised (ADI-R) algorithms for toddlers and young preschoolers (Kim and Lord, J Autism Dev Disord 42(1):82-93, 2012) in a non-US sample from ten sites in nine countries (n = 1,104). The construct validity indicated a good fit of

  7. Instant standard concept for data standards development

    NARCIS (Netherlands)

    Folmer, E.; Kulcsar, I.Z.; Roes, J.

    2013-01-01

    This paper presents the current results of an ongoing research about a new data standards development concept. The concept is called Instant Standard referring to the pressure that is generated by shrinking the length of the standardization process. Based on this concept it is estimated that the dev

  8. Promoting Innovation in the Mobile Sector : A Step-By-Step Methodology to Implement a Mobile Innovation Roadshow

    OpenAIRE

    World Bank

    2014-01-01

    Access to mobile communications has been linked with economic growth and the industry itself boosts local economies by creating high-value direct and indirect jobs. As part of its mobile innovation program, infoDev developed the concept of the mobile innovation roadshow with the overall objective to stimulate the development of an innovation and entrepreneurship ecosystem for mobile applic...

  9. The Association between Teachers' Child-Centered Beliefs and Children's Academic Achievement: The Indirect Effect of Children's Behavioral Self-Regulation

    Science.gov (United States)

    Hur, Eunhye; Buettner, Cynthia K.; Jeon, Lieny

    2015-01-01

    Background: Recent studies have suggested that teachers' psychological attributes can be an indicator of teacher quality (Rimm-Kaufman and Hamre in "Dev Psychol" 45(4):958-972. doi: 10.1037/a0015861 , 2010), and teachers' child-centered beliefs have been associated with children's academic achievement (Burchinal and Cryer in "Early…

  10. The Autism-Spectrum Quotient and Visual Search: Shallow and Deep Autistic Endophenotypes

    Science.gov (United States)

    Gregory, B. L.; Plaisted-Grant, K. C.

    2016-01-01

    A high Autism-Spectrum Quotient (AQ) score (Baron-Cohen et al. in "J Autism Dev Disord" 31(1):5-17, 2001) is increasingly used as a proxy in empirical studies of perceptual mechanisms in autism. Several investigations have assessed perception in non-autistic people measured for AQ, claiming the same relationship exists between…

  11. Appi - tarbijast võlgnik kolis välismaale! : kommentaar Riigikohtu lahenditele asjades 3-2-1-114-12 ja 3-2-1-123-12 / Karin Sein

    Index Scriptorium Estoniae

    Sein, Karin, 1974-

    2013-01-01

    Riigikohtu lahendist 3-2-1-114-12, milles vaieldi füüsilisest isikust võlgniku pankroti väljakuulutamise kohtualluvuse üle. Lahendist 3-2-1-123-12, milles vaieldi, kas ja millistel tingimustel on Eesti kohus pädev läbi vaatama hagi Eestist lahkunud tarbijast krediidisaaja vastu

  12. Attenuated Salmonella typhimurium delivering DNA vaccine encoding duck enteritis virus UL24 induced systemic and mucosal immune responses and conferred good protection against challenge

    Directory of Open Access Journals (Sweden)

    Yu Xia

    2012-07-01

    Full Text Available Abstract Orally delivered DNA vaccines against duck enteritis virus (DEV were developed using live attenuated Salmonella typhimurium (SL7207 as a carrier and Escherichia coli heat labile enterotoxin B subunit (LTB as a mucosal adjuvant. DNA vaccine plasmids pVAX-UL24 and pVAX-LTB-UL24 were constructed and transformed into attenuated Salmonella typhimurium SL7207 resulting SL7207 (pVAX-UL24 and SL7207 (pVAX-LTB-UL24 respectively. After ducklings were orally inoculated with SL7207 (pVAX-UL24 or SL7207 (pVAX-LTB-UL24, the anti-DEV mucosal and systemic immune responses were recorded. To identify the optimum dose that confers maximum protection, we used different doses of the candidate vaccine SL7207 (pVAX-LTB-UL24 during oral immunization. The strongest mucosal and systemic immune responses developed in the SL7207 (pVAX-LTB-UL24 (1011 CFU immunized group. Accordingly, oral immunization of ducklings with SL7207 (pVAX-LTB-UL24 showed superior efficacy of protection (60-80% against a lethal DEV challenge (1000 LD50, compared with the limited survival rate (40% of ducklings immunized with SL7207 (pVAX-UL24. Our study suggests that the SL7207 (pVAX-LTB-UL24 can be a candidate DEV vaccine.

  13. Improving component interoperability and reusability with the java connection framework (JCF): overview and application to the ages-w environmental model

    Science.gov (United States)

    Environmental modeling framework (EMF) design goals are multi-dimensional and often include many aspects of general software framework development. Many functional capabilities offered by current EMFs are closely related to interoperability and reuse aspects. For example, an EMF needs to support dev...

  14. Evaluation of the ADOS Revised Algorithm: The Applicability in 558 Dutch Children and Adolescents

    Science.gov (United States)

    de Bildt, Annelies; Sytema, Sjoerd; van Lang, Natasja D. J.; Minderaa, Ruud B.; van Engeland, Herman; de Jonge, Maretha V.

    2009-01-01

    The revised ADOS algorithms, proposed by Gotham et al. (J Autism Dev Disord 37:613-627, 2007), were investigated in an independent sample of 558 Dutch children (modules 1, 2 and 3). The revised algorithms lead to better balanced sensitivity and specificity for modules 2 and 3, without losing efficiency of the classification. Including the…

  15. A different development model in China’s western and eastern provinces?

    NARCIS (Netherlands)

    M.P. van Dijk (Meine Pieter)

    2011-01-01

    textabstractAbstract. Economic growth in China has declined between 2008 and 2009. The global financial crisis of 2008/9 has shown a number of structural weaknesses in the Chinese economy, such as the functioning of its capital and labor markets and the substantial income differences between the dev

  16. Kuidas taasluua minevikku / David Vseviov

    Index Scriptorium Estoniae

    Vseviov, David, 1949-

    2012-01-01

    Mineviku kirjeldamisega seoses peab silmas pidama sellega kaasnevat ettemääratud piiratust. Ajaloolise tõe väide saab olla pädev vaid kõige üldisemates raamides, jättes detailides vabaduse kõikvõimalikeks oletusteks

  17. Octamer-binding factor 6 (Oct-6/Pou3f1) is induced by interferon and contributes to dsRNA-mediated transcriptional responses

    NARCIS (Netherlands)

    E. Hofmann (Elisabeth); U. Reichart (Ursula); C. Gausterer (Christian); C. Guelly (Christian); D.N. Meijer (Dies); M. Müller (Martina); B. Strobl (Birgit)

    2010-01-01

    textabstractBackground: Octamer-binding factor 6 (Oct-6, Pou3f1, SCIP, Tst-1) is a transcription factor of the Pit-Oct-Unc (POU) family. POU proteins regulate key developmental processes and have been identified from a diverse range of species. Oct-6 expression is described to be confined to the dev

  18. Epidemiological analysis of data for scrapie in Great Britain

    NARCIS (Netherlands)

    Hagenaars, T.H.J.; Donnelly, C.; Ferguson, N.M.

    2006-01-01

    In recent years, the control or eradication of scrapie and any other transmissible spongiform encephalopathies (TSEs) possibly circulating in the sheep population has become a priority in Britain and elsewhere in Europe. A better understanding of the epidemiology of scrapie would greatly aid the dev

  19. Genetics Home Reference: isolated lissencephaly sequence

    Science.gov (United States)

    ... Long-term follow-up of type 1 lissencephaly: survival is related to neuroimaging abnormalities. Dev Med Child Neurol. 2011 May;53(5):417-21. doi: 10.1111/j.1469-8749.2011.03937.x. Epub 2011 Mar 17. Citation on PubMed Images Reviewed : July 2013 ...

  20. Inclusive business through partnerships

    NARCIS (Netherlands)

    R.J.M. van Tulder (Rob); A. Da Rosa (Andrea)

    2011-01-01

    textabstractAcademic and policy thought on economic growth and sustainable development in the 21st century represents a breach with traditional thinking. Traditional development approaches are getting replaced by new and more modern development thinking that adopts a contingency approach towards dev

  1. Stimuli responsive polymer/quantum dot hybrid platforms modified at the nanoscale

    OpenAIRE

    Tagit, Oya

    2010-01-01

    Quantum dots, QDs, receive growing attention from many research disciplines owing to their advantages as fluorescent probes including their nanoscale size (similar to biomolecules), high quantum yield and molar extinction coefficients, versatility in surface modification, broad excitation spectra (for multicolor imaging) and narrow band emission and tunable optical properties. Fabricating QD/polymer hybrid nanostructures enables realization of many potential applications as optoelectronic dev...

  2. Getting started with Hazelcast

    CERN Document Server

    Johns, Mat

    2015-01-01

    This book is a great introduction for Java developers, software architects, or DevOps looking to enable scalable and agile data within their applications. Providing in-memory object storage, cluster-wide state and messaging, or even scalable task execution, Hazelcast helps solve a number of issues that have troubled technologists for years.

  3. Advancing Research on Comparative and International Education in Asia: Contribution of the "Asia Pacific Education Review"

    Science.gov (United States)

    Gok, Enes; Weidman, John C.

    2015-01-01

    This article explored the contribution of Asia Pacific Education Review (APER) to expanding the scope of research on comparative and international education in Asia. We developed a rubric based on extensive studies (Rust et al. in "Comp Educ Rev," 43(1):86-109, 1999; Foster et al. in "Int J Educ Dev" 32:711-732, 2012) of…

  4. Assessing Longitudinal Change: Adjustment for Regression to the Mean Effects

    Science.gov (United States)

    Rocconi, Louis M.; Ethington, Corinna A.

    2009-01-01

    Pascarella (J Coll Stud Dev 47:508-520, 2006) has called for an increase in use of longitudinal data with pretest-posttest design when studying effects on college students. However, such designs that use multiple measures to document change are vulnerable to an important threat to internal validity, regression to the mean. Herein, we discuss a…

  5. The large radius human centrifuge 'A human hypergravity habitat, H

    NARCIS (Netherlands)

    Loon, J.J.W.A. van; Wuyts, F.; Bäcker, N.; Berte, J.; Bok, K.; Bos, J.; Groen, E.; Boyle, R.; Bravenoer, N.; Eekhoff, M.; Chouker, A.; Clement, G.; Cras, P.; Denise, P.; Felsenberg, D.; Fong, K.; Fuller, C.; Heer, M.; Hinghofer-Szalkay, H.; Iwase, S.; Karemaker, J.M.; Linnarsson, D.; Lüthen, C.; Mulder, E.; Narici, M.; Norsk, P.; Paloski, W.; Rutten, M.; Saggini, R.; Stephan, A.; Ullrich, O.; Vautmans, L.; Young, L.

    2009-01-01

    Over the last decades a significant body of knowledge has been gained on the adaptation of the human body going into near weightlessness conditions as well as for the re-adaptation to 1xg Earth conditions after an orbital space flight. Ground-based paradigms for microgravity simulation have been dev

  6. Orchestrating Docker

    CERN Document Server

    Holla, Shrikrishna

    2015-01-01

    If you are a competent developer or DevOps with a good understanding of Linux filesystems but want to manage and orchestrate Docker services, images, and products using a multitude of techniques, then this book is for you. No prior knowledge of Docker or container virtualization is required.

  7. Survey of ICT and Education in Africa : Côte D’Ivoire Country Report

    OpenAIRE

    Fall, Babacar

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The development of ICT in Ivorian colleges, universities and teaching institutions is expect...

  8. Characterization of African Bush Mango trees with emphasis on the differences between sweet and bitter trees in the Dahomey Gap (West Africa)

    NARCIS (Netherlands)

    Vihotogbe, R.

    2012-01-01

     African bush mango trees (ABMTs) are economically the most important species within the family of Irvingiaceae. They are priority trees producing non-timber forest products (NTFPs) and widely distributed in the humid lowland forests of West and Central Africa. To boost their production and dev

  9. Camera-Based Microswitch Technology to Monitor Mouth, Eyebrow, and Eyelid Responses of Children with Profound Multiple Disabilities

    Science.gov (United States)

    Lancioni, Giulio E.; Bellini, Domenico; Oliva, Doretta; Singh, Nirbhay N.; O'Reilly, Mark F.; Lang, Russell; Didden, Robert

    2011-01-01

    A camera-based microswitch technology was recently used to successfully monitor small eyelid and mouth responses of two adults with profound multiple disabilities (Lancioni et al., Res Dev Disab 31:1509-1514, 2010a). This technology, in contrast with the traditional optic microswitches used for those responses, did not require support frames on…

  10. High Flyers: Policies and Strategies that Boost Developmental Education Success in Florida's Community Colleges

    Science.gov (United States)

    Ajose, Lande; Bhatt, Ria Sengupta; Kaur, Gagandeep

    2011-01-01

    In 2010, Jobs for the Future (JFF) contracted BTW "informing change" (BTW) to conduct a study on developmental education (DevEd) practices and policies in the state of Florida. This study was undertaken with two purposes. First, JFF wanted to see what common threads could be identified among the strategies and approaches of community colleges that…

  11. Electroacoustic Music Is a "Subversion" to the Form of Traditional Music——An Idea From "Etudes Metro"—the Work of Pierre

    Institute of Scientific and Technical Information of China (English)

    Muyan Li

    2011-01-01

    We have studied"Metro Etudes"—the work of Pierre Schaeffer in this paper, and exploited the proposal of the concept of "concrete music". We discuss the basic concepts and characteristics of the current electroacoustic musics profoundly, analysis their dev

  12. A Parent-Mediated Intervention that Targets Responsive Parental Behaviors Increases Attachment Behaviors in Children with ASD: Results from a Randomized Clinical Trial

    Science.gov (United States)

    Siller, Michael; Swanson, Meghan; Gerber, Alan; Hutman, Ted; Sigman, Marian

    2014-01-01

    The current study is a randomized clinical trial evaluating the efficacy of Focused Playtime Intervention (FPI) in a sample of 70 children with Autism Spectrum Disorder. This parent-mediated intervention has previously been shown to significantly increase responsive parental communication (Siller et al. in "J Autism Dev Disord"…

  13. Disease: H00632 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 51C:307-17 (2009) PMID:9735377 (description) Casey B Two rights make a wrong: human left-right malformations.... Hum Mol Genet 7:1565-71 (1998) PMID:9572118 (description) Kosaki K, Casey B Gen...etics of human left-right axis malformations. Semin Cell Dev Biol 9:89-99 (1998) PMID:11471159 (description) Casey

  14. 77 FR 795 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2012-01-06

    ..., Illinois 60690-1414: 1. Thomas Benton Hunter, III, Lake Forest, Illinois; as trustee of the Hunter 2012 Annuity Trust, and the Hunter 2012 Annuity Trust, both in Chicago, Illinois; to join the existing Steans.... Board of Governors of the Federal Reserve System, January 3, 2012. Robert deV. Frierson,...

  15. Electrical Control, Read-out and Initialization of Single Electron Spins

    NARCIS (Netherlands)

    Shafiei, M.

    2013-01-01

    An electron, in addition to its electric charge, possesses a small magnetic moment, called spin. The spin of an electron can point parallel (spin-up) or antiparallel (spin-down) to the magnetic field. These two states are analogous to zero and one of the logical bit in current digital electronic dev

  16. Piraatlus Guinea lahes ja Nigeerias / Eero Tepp

    Index Scriptorium Estoniae

    Tepp, Eero

    2013-01-01

    Guinea lahes lokkava piraatluse põhjused ja tegurid, mis seda soodustavad: seaduselüngad, looduslikud tingimused, ebapädev korrakaitse, poliitiline olustik, kultuuriline vastuvõetavus, majanduslik tasuvus. Sõjalised ja mittesõjalised meetmetest, mida rakendatakse piraatlusevastases võitluses

  17. Barnacle larval destination: piloting possibilities by bacteria and lectin interaction

    Digital Repository Service at National Institute of Oceanography (India)

    Khandeparker, L.; Anil, A.C.; Raghukumar, S.

    . Reprod. Dev. 22, 67–76. Cooksey, K.E., 1992. Extracellular polymers in biofilms. Biofilms: Science and Technology. Kluwer Academic Publishing, The Netherlands, pp. 137–147. Costerton, J.W., Geesey, G.G., Cheng, K.-J., 1978. How bacteria stick. Sci. Am...

  18. Automatic discrimination between laughter and speech

    NARCIS (Netherlands)

    Truong, K.; Leeuwen, D. van

    2007-01-01

    Emotions can be recognized by audible paralinguistic cues in speech. By detecting these paralinguistic cues that can consist of laughter, a trembling voice, coughs, changes in the intonation contour etc., information about the speaker’s state and emotion can be revealed. This paper describes the dev

  19. On the Integration of Automatic Deployment into the ABS Modeling Language

    NARCIS (Netherlands)

    Gouw, C.P.T. de; Lienhardt, M.; Mauro, J.; Nobakht, B.; Zavattaro, G.; Dustdar, S.; Leymann, F.; Villari, M.

    2015-01-01

    In modern software systems, deployment is an integral and critical part of application development (see, e.g., the DevOps approach to software development). Nevertheless, deployment is usually overlooked at the modeling level, thus losing the possibility to perform deployment conscious decisions dur

  20. Student Perceptions of Effective Instruction and the Development of Critical Thinking: A Replication and Extension

    Science.gov (United States)

    Loes, Chad N.; Salisbury, Mark H.; Pascarella, Ernest T.

    2015-01-01

    This study utilized data from the Wabash National Study of Liberal Arts Education to test the robustness of research conducted by Pascarella et al. ("J Coll Stud Dev" 37:7-19, 1996) that explored the relationship between student perceptions of exposure to organized and clear instruction and growth in critical thinking skills among…

  1. Non-diffractive optically variable security devices

    NARCIS (Netherlands)

    Renesse, R.L. van

    1991-01-01

    At the past optical security conferences attention was focused on diffractive structures, e.g. holograms, embossed gratings and thin—film devices, as security elements on valuable documents. The main reasons for this emphasis are, that the iridescent effect of such diffractive optically variable dev

  2. Development of novel repellents using structure-activity modeling of compounds in the USDA archival database

    Science.gov (United States)

    The United States Department of Agriculture (USDA) has developed repellents and insecticides for the U.S. military since 1942. Repellency and toxicity data for over 30,000 compounds are contained within the USDA archive. Repellency data from subsets of similarly structured compounds were used to dev...

  3. Autism and Dimensionality: Differences between Copying and Drawing Tasks

    Science.gov (United States)

    Sheppard, Elizabeth; Ropar, Danielle; Mitchell, Peter

    2009-01-01

    Previous research suggests individuals with autism may be less influenced by a three-dimensional interpretation when copying line drawings (Sheppard et al. "J Autism Dev Disord" 37:1913-1924, 2007). The current research aimed to determine whether this reduced dimensionality effect extends to drawings of an actual object. Twenty-four children and…

  4. Cassandra high availability

    CERN Document Server

    Strickland, Robbie

    2014-01-01

    If you are a developer or DevOps engineer who understands the basics of Cassandra and are ready to take your knowledge to the next level, then this book is for you. An understanding of the essentials of Cassandra is needed.

  5. Anterior fontanelle pressure monitoring in infants

    NARCIS (Netherlands)

    W.C.G. Overweg-Plandsoen

    1990-01-01

    textabstractThe objectives of this study were 1 To evaluate whether the R TT could be used as a 'fontanometer'. The literature on non-invasive ICP measurement techniques used in infants and children was studied to avoid problems already encountered by others. Subsequently, a special R TT holding dev

  6. 18F-FLT PET in hematologic disorders : A novel technique to analyze the bone marrow compartment

    NARCIS (Netherlands)

    Agool, Ali; Schot, Bart W.; Jager, Pieter L.; Vellenga, Edo

    2006-01-01

    Few diagnostic procedures are available to determine the degree of bone marrow cellularity and the numbers of cycling cells in patients with bone marrow disorders. Noninvasive imaging of the bone marrow compartment may be helpful. The PET tracer 3'-fluoro-3'-deoxy-L-thymidine (F-18-FLT) has been dev

  7. Bicycle Rider Control: Observations, Modeling & Experiments

    NARCIS (Netherlands)

    Kooijman, J.D.G.

    2012-01-01

    Bicycle designers traditionally develop bicycles based on experience and trial and error. Adopting modern engineering tools to model bicycle and rider dynamics and control is another method for developing bicycles. This method has the potential to evaluate the complete design space, and thereby dev

  8. NEONATAL EXPOSURE TO TRIMETHYLTIN DISRUPTS SPATIAL DELAYED ALTERNATION LEARNING IN PREWEANLING RATS

    Science.gov (United States)

    Trimethyltin is an organotin compound that produces potent neurotoxicity in both adult and developing animals. he limbic system is a primary CNS target site for this toxicity and a prominent behavioral effect of TMT is disruption of learning and memory. mpairment of cognitive dev...

  9. Retrofit of Ressalat jacket platform (Persian Gulf) using friction damper device

    DEFF Research Database (Denmark)

    Komachi, Y.; Tabeshpour, M. R.; Golafshani, A. A.;

    2011-01-01

    A friction damper device (FDD) is used for vibration control of an existing steel jacket platform under seismic excitation. First, the damping is presented for vibration mitigation of structures located in seismically active zones. A new method for quick design of friction or yielding damping dev...

  10. Nanowire-based gas sensors

    NARCIS (Netherlands)

    Chen, X.; Wong, C.K.Y.; Yuan, C.A.; Zhang, G.

    2013-01-01

    Gas sensors fabricated with nanowires as the detecting elements are powerful due to their many improved characteristics such as high surface-to-volume ratios, ultrasensitivity, higher selectivity, low power consumption, and fast response. This paper gives an overview on the recent process of the dev

  11. Methyl Farnesoate a naturally occurring juvenoid that accelerates reproductive development in Caribbean Fruit Flies

    Science.gov (United States)

    Methyl farnesoate, the immediate biosynthetic precursor of juvenile hormone III (JH III) and the bisepoxide homolog of JH III was identified from hemolymph of adult males and females of the Caribbean fruit fly. Application of methyl farnesoate to newly eclosed flies resulted in precocious sexual dev...

  12. Hyperdev: Hypertext tool to support object-oriented software development

    International Nuclear Information System (INIS)

    The authors propose a software tool, based on hypertext techniques, to support the object-oriented development of scientific applications. Within HyperDev, all kinds of software information such as plain text, formatted text, graphics and code are connected through links allowing for different views of the same object and, consequently, achieving a better understanding of the software components

  13. Survey of ICT and Education in Africa : Niger Country Report

    OpenAIRE

    Tutu Agyeman, Osei

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. The Republic of Niger is mostly desert and it is the poorest country in the world. Subsisten...

  14. Survey of ICT and Education in Africa : Botswana Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Botswana is a small, dynamic country with visionary leadership particularly in the sector of...

  15. Survey of ICT and Education in Africa : South Africa Country Report

    OpenAIRE

    Isaacs, Shafika

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. In all the different facets of the ICTs for education prism, South Africa boasts more than a...

  16. The Relationship between Sensory Sensitivity and Autistic Traits in the General Population

    Science.gov (United States)

    Robertson, Ashley E.; Simmons, David R.

    2013-01-01

    Individuals with Autism Spectrum Disorders (ASDs) tend to have sensory processing difficulties (Baranek et al. in J Child Psychol Psychiatry 47:591-601, 2006). These difficulties include over- and under-responsiveness to sensory stimuli, and problems modulating sensory input (Ben-Sasson et al. in J Autism Dev Disorders 39:1-11, 2009). As those…

  17. Does WISC-IV Underestimate the Intelligence of Autistic Children?

    Science.gov (United States)

    Nader, Anne-Marie; Courchesne, Valérie; Dawson, Michelle; Soulières, Isabelle

    2016-01-01

    Wechsler Intelligence Scale for Children (WISC) is widely used to estimate autistic intelligence (Joseph in The neuropsychology of autism. Oxford University Press, Oxford, 2011; Goldstein et al. in "Assessment of autism spectrum disorders." Guilford Press, New York, 2008; Mottron in "J Autism Dev Disord" 34(1):19-27, 2004).…

  18. The Autism Diagnostic Observation Schedule, Module 4: Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (N = 93)

    Science.gov (United States)

    de Bildt, Annelies; Sytema, Sjoerd; Meffert, Harma; Bastiaansen, Jojanneke A. C. J.

    2016-01-01

    This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in "J Autism Dev Disord" 44(8):1996-2012, 2014) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the revised algorithm ASD cut-off…

  19. Recent advances in silage microbiology

    Science.gov (United States)

    Recent advances in our understanding of silage microbiology are reviewed. The ability to extract microbial DNA from silages, amplify portions of DNA, and use the amplified regions to identify strains of microorganisms is at the core of the changes occurring recently in silage microbiology. These dev...

  20. Getting started with tmux

    CERN Document Server

    Quinn, Victor

    2014-01-01

    The book is intended for software developers, DevOps engineers, and other professionals who make heavy use of the terminal in their daily workflow. Some familiarity with the terminal is useful but no prior experience with tmux or other terminal multiplexers (such as GNU Screen) is required.

  1. Genetics Home Reference: Lesch-Nyhan syndrome

    Science.gov (United States)

    ... 12. Saito Y, Takashima S. Neurotransmitter changes in the pathophysiology of Lesch-Nyhan syndrome. Brain Dev. 2000 Sep;22 Suppl 1:S122-31. Review. Visser JE, Bär PR, Jinnah HA. Lesch-Nyhan disease and the basal ganglia. Brain Res Brain Res Rev. 2000 Apr;32( ...

  2. DEVELOPMENT AND EVALUATION OF A REAL-TIME TAQMAN RT-PCR ASSAY FOR THE DETECTION OF INFECTIOUS BRONCHITIS VIRUS FROM INFECTED CHICKENS

    Science.gov (United States)

    It is important to rapidly differentiate infectious bronchitis virus (IBV) from disease agents like highly pathogenic avian influenza virus and exotic Newcastle disease virus, because those diseases can be extremely similar in the early stages of their pathogenicity. In this study, we report the dev...

  3. Does Child Labor Always Decrease with Income? An Evaluation in the Context of a Development Program in Nicaragua

    OpenAIRE

    Del Carpio, Ximena V.

    2008-01-01

    This paper investigates the relationship of household income with child labor. The analysis uses a rich dataset obtained in the context of a conditional cash transfer program in a poor region of Nicaragua in 2005 and 2006. The program has a strong productive emphasis and seeks to diversify the work portfolio of beneficiaries while imposing conditionalities on the household. The author dev...

  4. State and dissociation mechanisms of mixed-ligand acidoporphyrin complexes of metals in sulfuric acid solutions

    International Nuclear Information System (INIS)

    Dissociation of indium complexes with tetraphenylporphyrin (H2 TPP) and complexes (Cl)In TPP(X)4, where TPP(X)42--dianion of TPP substituted in para-positions of phenyls with OCH3, Br, NO2 groups, in sulfuric acid solutions has been studied by spectrophotometric method. It is shown that complex (Cl)In TPP associated with proton of the solvent dissociates by multistage mechanism, protolytic dissociation of metalloporphyrin under the effect of sulfuric acid molecules being the limiting stage of the process. Proton associated with metalloporphyrin produces inhibiting effect on dissociation

  5. Ca2(+)-sensitive binding of thrombospondin to U937 cells is due to the formation of calcium precipitate in the binding medium.

    OpenAIRE

    Sun, X.; Mosher, D F

    1991-01-01

    Thrombospondin (TSP) binds to U937 monocytic cells in a Ca2(+)-enhancible and EDTA-inhibitable manner (Silverstein, R. L., and R. L. Nachman. 1987. J. Clin. Invest. 79:867-874; Silverstein, R. L., A. S. Asch, and R. L. Nachman. 1989. J. Clin. Invest. 84:546-552). We reproduced the results when RPMI cell culture medium, but not when HBSS was used as binding medium. Addition of 1 mM Ca2+ to RPMI medium increased the binding of TSP to suspended U937 cells more than eightfold; the increase was bl...

  6. Écologie et conservation des abeilles sauvages le long d'un gradient d'urbanisation

    OpenAIRE

    Fortel, Laura

    2014-01-01

    Depuis des années, on observe un déclin des insectes pollinisateurs. La perte d’habitats naturels, en partie liée àl’urbanisation, est considérée comme l’une des causes majeures de ce déclin. Des populations d’abeilles(Hymenoptera : Anthophila) se maintiennent cependant en milieux urbains. La structure de leurs communautés,ainsi que leurs comportements de butinage et de nidification peuvent être affectés par les perturbations liées àl’urbanisation. Notre objectif était d’évaluer l’ampleur de ...

  7. Les plantes tinctoriales dans l'économie du Vaucluse au XIXe siècle

    OpenAIRE

    Peeters, Alice

    2003-01-01

    L'histoire mouvementée des plantes tinctoriales dans le Vaucluse au XIXe siècle permet de distinguer trois cas nettement différents : 1) le déclin d'anciennes cultures comme celle du safran, ou de plantes de cueillette comme le fustet ou la graine d'Avignon, déclin lié au passage d'un très petit artisanat de teinturerie à une industrie ayant besoin d'une production beaucoup plus importante ; 2) les essais de cultures nouvelles comme celle du pastel qui, imposées lors du Blocus continen...

  8. Purification and biochemical characterization of the complete structure of a proteolytically modified beta-2-microglobulin with biological activity

    DEFF Research Database (Denmark)

    Nissen, Mogens Holst; Thim, L; Christensen, M

    1987-01-01

    . (1985) Clin. Chem. 31, 1411-1412; Nissen et al. (1984) Clin. Chim. Acta 141, 41-50]. In the present study we describe the purification and characterization of this modified human serum beta-2-m from patients with small-cell lung cancer. Purified urinary beta-2-m was added to the serum samples incubated...... analyzed by sodium dodecyl sulphate/polyacrylamide gel electrophoresis and analytical isoelectric focusing respectively. Amino acid analysis of m-beta-2-m revealed that the protein is missing one lysine residue compared to the composition deduced from the cDNA sequence of beta-2-m. Amino acid sequence...

  9. Disease: H00323 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available kettsia within the family Rickettsiaceae in the order Rickettsiales. The diseases present with high fever, a...orne rickettsioses around the world: emerging diseases challenging old concepts. Clin Microbiol Rev 18:719-5...PMID:15225980 (description) Parola P Tick-borne rickettsial diseases: emerging risks in Europe. Comp Immunol... Microbiol Infect Dis 27:297-304 (2004) PMID:18755389 (description) Cazorla C, Socolovschi C, Jensenius M, Parola P Tick-borne diseas...es: tick-borne spotted fever rickettsioses in Africa. Infect Dis Clin North Am 22:531-44, ix-x (2008) ...

  10. Photocarcinogenesis and toxicity of benzoyl peroxide in hairless mice after simulated solar radiation

    DEFF Research Database (Denmark)

    Lerche, Catharina M; Philipsen, Peter A; Poulsen, Thomas;

    2010-01-01

    Topical benzoyl peroxide (BPO) gel has long been used to treat acne vulgaris and has recently been combined with clindamycin (BPO-clin). No skin malignancies have been reported after clinical use of BPO, but there has been concern about the possible carcinogenicity of BPO alone and in combination...... with UV radiation. BPO can promote skin tumorigenesis in a mouse skin chemical carcinogenesis model. As acne vulgaris is frequently localized on sun-exposed areas, we investigated whether BPO or BPO-clin accelerates photocarcinogenesis in combination with simulated solar radiation (SSR) in 12 groups of...

  11. Approach To The First Unprovoked Seizure- PART II

    Directory of Open Access Journals (Sweden)

    Mohammad GHOFRANI

    2013-11-01

    , adolescents and young adult. Seizure 1997;6:461-565.39.Berg AT, Shinnar S, Levy SR, Testa FM, et al. Early development of intractable epilepsy in children: A prospective study. Neurology 2001;56:1445-1452.40.Berg At, Shinnar S. The risk of seizure recurrence following a first unprovoked seizure: A quantitative review. Neurology 1991;41:955-972.41.Camfield PR, Camfield CS, Dooley JM, et al. Epilepsy after a first unprovoked seizure in childhood, Neurology 1985;35:1657-1660.42.Commission on epidemiology and prognosis. International League Against Epilepsy. Guidelines for epidemiologic studies on epilepsy. Epilepsia 1993;37:592-596.43.Annegers JF, Shirts SB, Hauser WA, et al. Risk of recurrence after an initial unprovoked seizure. Epilepsia 1986;27:43-50.44.Shinnar S, Berg AT, Moshe SL, Shinnar R. How long do new –onset seizures in children last? Ann Neurol 2001;49:659-664.45.Camfield P, Camfield C, Dooley J, et al. A randomized study of carbamazepine versus no medication after a first unprovoked seizure in childhood. Neurology 1989;39:851-852.46.Chandra B. First Seizure in adult: to treat or not to treat. Clin Neurol Neurosurg 1992;94:861-863.47.Musico M, Beghi E, Solari A, Viani F. Treatment of first Tonic-Clonic Seizure does not improve the prognosis of epilepsy. Neurology 1997;49:991-998.48.American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy (RE9537. Approach To The First Unprovoked Seizure-PART II. Pediatrics 1995;96:538-540.49.Yerby MS. Teratogenic effects of antiepileptic drugs: what do we advise patients? Epilepsia 1997;38-957-958.50.Vinig EP, Melits ED. Dorsen MM, et al. Psychologic and behavioral effects of antiepileptic drugs in children: A double-blind comparison between Phenobarbital and valproic acid. Pediatrics 1987;80: 165-174.51.Berg I, Butler A, Ellis M, Foster J. Psychiatric aspects of epilepsy in childhood treated with carbamazepine, phenytoin, or sodium valporate: a random trial. Dev Med Child Nerol 1993

  12. Comparison of Deflazacort and Prednisone in Duchenne Muscular Dystrophy

    Directory of Open Access Journals (Sweden)

    Parvaneh KARIMZADEH

    2012-03-01

    -Apr;10(2:138-51. Escolar DM, Leshner RT. Muscular dystrophies. In: Swaiman KF, Ashwal S, Ferriero DM. Pediatric Neurology. 4th ed. Philadelphia: Mosby; 2006. p. 1967-86. Sarnat HB, Menkes JH. Disease of the motor unit. In: Menkes JH, Sarnat HB, editors. Child Neurology. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. p. 984-9. Biggar WD, Politano L, Harris VA, Passamano L, Vajsar J, Alman B, et al. Deflazacort in duchenne muscular dystrophy: a comparison of two different protocols. Neuromuscul disord 2004 Sep;14(8-9:476-82. Radley HG, De Luca A, Lynch GS, Grounds MD. Duchenne muscular dystrophy: focus on pharmaceutical and nutritional interventions. Int J Biochem Cell Biol 2007;39(3:469-77.Biggar WD, Klamut HJ, Demacio PC, Stevens DJ. Duchenne muscular dystrophy: current knowledge, treatment and future prospects. Clin Orthop Relat Res 2002 Aug;401:88-106.Sohn RL, Gussoni E. Stem cell therapy for muscular dystrophy. Expert Opin Biol Ther 2004 Jan;4(1:1-9.Houde S, Filiatrault M, Fournier A, Dube J, D’Arcy S, Berube D et al. Deflazacort use in duchenne muscular dystrophy: an 8-year follow-up. Pediatr Neurol 2008 Mar;38(3:200-6.Bonifati MD, Ruzza G, Bonometto P, Berardinelli A, Gorni K, Orcesi K et al. A multicenter double-bind randomized trial of deflazacort versus prednisone in Duchenne muscular dystrophy: analysis after 2 years. Basic Appl Myol 2000;10:171-5.Reitter B. Deflazacort vs. prednisone in Duchenne muscular dystrophy: trends of an ongoing study. Brain Dev 1995;17 Suppl:39-43.Polgar G, Promadhat V. Standard values. In: pulmonary function testing in children: techniques and standards. Philadelphia: W.B. Saunders, 1971:102-3.Biggar WD, Gingras M, Febling DL, Harris VA, Steele CA. Deflazacort treatment of Duchenne muscular dystrophy. J Pediatr 2001 Jan;138(1:45-50. 

  13. Role of Prostate Specific Antigen, Digital Rectal Examination and Trans Rectal Ultrasonography in the Diagnosis of Prostate Cancer in Patients with Lower Urinary Tract Symptoms

    Directory of Open Access Journals (Sweden)

    Sunanda De

    2014-02-01

    Conclusion: None of the single screening tools had that much efficacy in differentiating carcinoma of prostate from benign prostatic hyperplasia in patients with LUTS. Combining PSA, DRE and TRUS increases sensitivity, specificity and PPV of PC detection. [Arch Clin Exp Surg 2014; 3(1.000: 40-46

  14. Auditing of prescriptions in relation to diarrhea in children below 5 years of age: a multicenter study

    Directory of Open Access Journals (Sweden)

    Lokendra Sharma

    2015-12-01

    Conclusions: Antimicrobials should be prescribed rationally for pediatric patients suffering from diarrhea to avoid potential adverse events and increased cost of the treatment . Regular prescription audits in hospitals should be undertaken to promote rational use of drugs. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1208-1213

  15. Contemplation on new drug approvals by U.S. FDA, 2011-2015

    Directory of Open Access Journals (Sweden)

    Bhaven C. Kataria

    2016-02-01

    Conclusions: For new drugs approved between 2011 and 2015, the U.S. FDA was first to approve majority of new drugs. There was upward trend of new drug approvals in antineoplastic therapeutic area. [Int J Basic Clin Pharmacol 2016; 5(1.000: 55-59

  16. Comparison of new drug approval by regulatory agencies of US, EU and India

    Directory of Open Access Journals (Sweden)

    Bhaven C. Kataria

    2016-02-01

    Conclusions: For new drugs approved between 2011 and 2015, India has lagged behind the US and the EU in approval of new drugs. There was no difference in the patterns of new drug approvals with respect to the therapeutic areas. [Int J Basic Clin Pharmacol 2016; 5(1.000: 112-115

  17. Antibiotic utilization evaluation of inpatient and outpatient prescriptions in a rural general hospital in Iran

    Directory of Open Access Journals (Sweden)

    Aida Sefidani Forough

    2015-06-01

    Conclusion: Our study showed that implementation of strict regulations for antibiotic use is extremely needed in this rural hospital. Establishing local guidelines, providing adequate education for healthcare professionals and putting restrictions for broad-spectrum antibiotic use can be beneficial. [Int J Basic Clin Pharmacol 2015; 4(3.000: 531-536

  18. Predictive Factors for Mortality and Morbidity of Ruptured Abdominal Aortic Aneurysm Repair

    Directory of Open Access Journals (Sweden)

    Manabu Shiraishi

    2012-04-01

    Conclusions: Emergency open repair can be safely performed in patients for infrarenal rAAA. In particular, we identified specific independent predictive factors of clinical examination and laboratory studies for mortality, major morbidity and renal insufficiency. [Arch Clin Exp Surg 2012; 1(2.000: 94-101

  19. Use of garenoxacin: a new generation antibiotic for surgical infections

    Directory of Open Access Journals (Sweden)

    J. Rodrigues

    2015-02-01

    Conclusions: Administration of garenoxacin used as empirical therapy for surgical prophylaxis and as switch therapy in patients with DFU s and post-surgical infectious wounds for the period of 5-7 days has been found effective indicating its wide spectrum of action. [Int J Basic Clin Pharmacol 2015; 4(1.000: 144-147

  20. Comparative study of in-vitro antimicrobial activity and phytochemical composition of Sida cuneifolia fruits, leaves, and stem bark extracts

    Directory of Open Access Journals (Sweden)

    Rebecca Nalubega

    2014-10-01

    Conclusion: The study provides scientific evidence for ethno-veterinary use of S. cuneifolia leaves, fruits and stem bark, and this can be exploited in the transformative development of ethno-medicine. [Int J Basic Clin Pharmacol 2014; 3(5.000: 781-788

  1. Incidence of cardiac conduction disorders in patients with rheumatic disease receiving hydroxychloroquine

    Directory of Open Access Journals (Sweden)

    Vijaya Prasanna Parimi

    2015-06-01

    Conclusion: This study highlights need for periodic cardiac evaluation of patients receiving long-term antimalarials. Reversibility of antimalarial toxicity is also highlighted in this study. Conduction disorders observed were similar to that expected in general population thus adding further evidence on safety of HCQ. [Int J Basic Clin Pharmacol 2015; 4(3.000: 565-567

  2. Anti-tussive, muco-suppressant and expectorant properties, and the safety profile of a hydro-ethanolic extract of Scoparia dulcis

    Directory of Open Access Journals (Sweden)

    George A. Koffuor

    2014-06-01

    Conclusion: The results showed that S. dulcis extract has anti-tussive, muco-suppressant and, expectorant and/or mucolytic properties; making it a possible remedy for asthma, and obstructive pulmonary disease. [Int J Basic Clin Pharmacol 2014; 3(3.000: 447-453

  3. Genetics Home Reference: hidradenitis suppurativa

    Science.gov (United States)

    ... Apr;60(4):539-61; quiz 562-3. doi: 10.1016/j.jaad.2008.11.911. Review. ... Acad Dermatol. 2009 Jul;61(1):51-7. doi: 10.1016/j.jaad.2009.02.013. Epub ... Dermatol Clin. 2010 Oct;28(4):779-93. doi: 10.1016/j.det.2010.07.003. Review. ...

  4. Immunity

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    970239 The effect of interleukin 6 against cytopeniaand suppressed phagocytosis of macrophage caused bychemotherapy. ZHANG Lichao(张利朝), et al.Tangdu Hosp, 4th Milit Med Univ, Xian, 710038. ChinJ Clin Oncol 1997; 24(4): 252-255. Objective: To explore The effect of interleukin 6against cytopenia and suppressed phagocytosis ofmacrophage caused by chemotherapy. Methods:Inter-

  5. Lymphatic system and lymphoma

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    970385 The changes of cell immune function in ap-tients with non-Hodgkin’s lymphoma by flow cytome-try analysis. LU Ming(吕鸣), et al. Clin ImmunolCenter, Changzheng Hosp, 2nd Milit Med Univ, Shang-hai, 200003. Shanghai Med J 1997; 20(2): 73-75.

  6. Immune thrombocytopenic purpura following Varicella zoster infection

    Directory of Open Access Journals (Sweden)

    Alper Dai

    2011-03-01

    Full Text Available Although thrombocytopenia is a rarely observed complicationfollowing chickenpox, it can lead to serious bleedingproblems. In order to underline rare hematologiccomplications of varicella infection and the importanceof vaccination, here we reported a seven year old boywho developed severe thrombocytopenia duringvaricella infection and gave good response to intravenousimmunoglobulin therapy. J Clin Exp Invest 2011;2(1: 85-87

  7. Posterior belly of the digastric muscle: An important landmark for various head and neck surgeries

    Directory of Open Access Journals (Sweden)

    Vrinda Hari Ankolekar

    2015-04-01

    Conclusion: As the PBD muscle is an important surgical landmark, the present study adds to the existing knowledge about it. The present study has also included few newer landmarks, which were not given importance in the previous studies. [Arch Clin Exp Surg 2015; 4(2.000: 79-82

  8. Evaluation of Early and Late Term Outcomes of Radiofrequency Surgery in the Treatment of Inferior Turbinate Hypertrophy

    Directory of Open Access Journals (Sweden)

    Murat Salihoglu

    2014-02-01

    Conclusion: Inferior turbinate RFA can be used alone effectively in the treatment of nasal obstruction caused by ITH. Results of inferior turbinate RFA are satisfactory for at least one year without causing impairment in physiologic mucociliary activity or other adverse effects. [Arch Clin Exp Surg 2014; 3(1.000: 34-39

  9. Cost analysis of different brands of antianginal drugs available in India

    Directory of Open Access Journals (Sweden)

    L. Akila

    2015-10-01

    Conclusions: To increase the benefit to the patient and reduce drug in compliance, doctors should be trained to be familiar from internship period itself about the brand names of cost-effective drugs with good safety profile for a long period. [Int J Basic Clin Pharmacol 2015; 4(5.000: 860-863

  10. A comparative study of oral tapentadol with thoracic epidural analgesia versus intravenous tramadol and paracetamol combination for postoperative analgesia in off pump CABG

    Directory of Open Access Journals (Sweden)

    Himanshu A. Shah

    2013-12-01

    Conclusions: Our study concludes that Tapentadol with Thoracic epidural is very much effective as a multimodal analgesia approach in controlling acute postoperative pain after CABG. Tapentadol is quite a newer drug so its usefulness for other patients and different surgeries is still to be debated. [Int J Basic Clin Pharmacol 2013; 2(6.000: 723-727

  11. Genetics Home Reference: glucose-galactose malabsorption

    Science.gov (United States)

    ... Turk E. Intestinal absorption in health and disease--sugars. Best Pract Res Clin Gastroenterol. 2003 Dec;17(6):943-56. Review. ... resources on this site should not be used as a substitute for professional medical care or advice. Users with ...

  12. Student's perception and experience of computer assisted learning as a teaching method in experimental pharmacology

    Directory of Open Access Journals (Sweden)

    Deepika Tikoo

    2015-12-01

    Conclusion: The study demonstrates the effectiveness of CAL in teaching experimental pharmacology concepts and the students felt that this method helped them in a better understanding of the topic as the effects were clearly visualized on the screen and that such simulations need to be a part of the standard curriculum. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1168-1174

  13. Disease: H00408 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ation, fatigue, weight loss and so on. It is recognized that both genetic and environmental determinants are...diagnostics in diabetes mellitus. Clin Chem Lab Med 44:133-7 (2006) PMID:12116173 (environmental factor) Ake...ogy of type 1 diabetes. Am J Med Genet 115:18-29 (2002) PMID:17203405 (environmental factor) Peng H, Hagopia

  14. Disease: H00576 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available a deficiency of 2-laminin in the basement membrane. Developmental disorder; Kidne...1-5 (2006) PMID:18094725 (gene, description) Gubler MC Inherited diseases of the glomerular basemen...n CE, Segal Y Genetic disorders of glomerular basement membranes. Nephron Clin Pract 118:c9-c18 (2011) ...

  15. A case with Lichen planus in the lines of Blaschko

    Directory of Open Access Journals (Sweden)

    Metehan Gençoğlu

    2011-12-01

    Full Text Available Lichen planus is an inflammatory disorder that may involveskin and mucous membranes. Linear lichen planusis a rare disorder occurring in approximately 0.2% of patientswith lichen planus. We report a case of linear lichenplanus on the upper extremity which lesions followed thelines of Blaschko. J Clin Exp Invest 2011; 2 (4: 430-432

  16. Evaluation of antioxidant effect of Salacia oblonga against aluminum chloride induced visceral toxicity in albino rats

    Directory of Open Access Journals (Sweden)

    S. Nathiya

    2014-04-01

    Result: The results showed that S. oblonga produced significant (pS. oblonga protects against aluminuminduced oxidative stress, which is an important finding that further reinforces the antioxidant properties of this natural product. [Int J Basic Clin Pharmacol 2014; 3(2.000: 315-319

  17. Disease: H00259 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Apparent mineralocorticoid excess (AME) syndrome is characterized by hypertension, low plasma renin and ald...rtension. Best Pract Res Clin Endocrinol Metab 20:337-53...071] Dexamethasone [DR:D00292] ICD-10: E27.4 I15.2 OMIM: 218030 207765 PMID:16980198 Hammer F, Stewart PM Cortisol metabolism in hype

  18. Toxicological evaluation and oral glucose tolerance test of ethanolic leaf extract of Barleria cristata L. in wistar albino rats

    Directory of Open Access Journals (Sweden)

    R. Narmadha

    2013-12-01

    Conclusion: EtBc was revealed the non-toxic nature used for acute toxicity studies and among various doses of this extract, 400 mg/kg brought an effective hypoglycemic activity in wistar albino rats. [Int J Basic Clin Pharmacol 2013; 2(6.000: 742-746

  19. A randomised control study on neurosensory outcomes of ilioingunal neurectomy in Lichtenstein's hernia repair

    Directory of Open Access Journals (Sweden)

    Annappa Kudva

    2016-06-01

    Conclusion: The severity of pain in the neurectomy group was less than the control group. There were no significant dif- ferences in the neurosensory outcomes of prophylactic ilioinguinal neurectomies in open mesh hernia repair compared to nerve preservation and hence prophylactic neurectomy is presently the choice of most surgeons. [Arch Clin Exp Surg 2016; 5(2.000: 94-99

  20. Genetics Home Reference: Huntington disease-like syndrome

    Science.gov (United States)

    ... what to consider in patients with a negative Huntington's disease gene test. Nat Clin Pract Neurol. 2007 Sep;3( ... San C, Bellance R, Brice A, Durr A. Huntington's disease-like phenotype due to trinucleotide repeat expansions in the TBP and JPH3 genes. Brain. 2003 Jul;126(Pt 7):1599-603. ...

  1. Drug utilization pattern of antimicrobial agents in an outpatient department of otorhinolaryngology in a tertiary care hospital: a prospective, cross-sectional study

    Directory of Open Access Journals (Sweden)

    Sanket B. Sathiya

    2016-02-01

    Conclusions: Our study shows some rational prescription patterns like less utilization of antimicrobials in ENT infections and were according to standard treatment guideline. The results of this study will be useful in future for making standard treatment guidelines. It also promotes the rational prescription and rational use of drugs. [Int J Basic Clin Pharmacol 2016; 5(1.000: 65-69

  2. Evaluation of anti-depressant effect of lemon grass (Cymbopogon citratus in albino mice

    Directory of Open Access Journals (Sweden)

    Sujata Dudhgaonkar

    2014-08-01

    Results: Lemon grass at the above doses significantly reduced the immobility time in both the tests compared with the control (C. citratus has significant anti-depressant activity comparable to imipramine. [Int J Basic Clin Pharmacol 2014; 3(4.000: 656-660

  3. Disease: H00609 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00609 46,XY disorders of sex development (Other), including: Persistent Mullerian ...duct syndrome; Hypospadias; Cryptorchidism 46,XY disorders of sex development (46,XY DSD) with other various...(description, gene) Hughes IA Disorders of sex development: a new definition and ...onca BB, Domenice S, Arnhold IJ, Costa EM 46,XY disorders of sex development (DSD). Clin Endocrinol (Oxf) 70

  4. Disease: H00885 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available PMID:15708290 (description) Passeron T, Mantoux F, Ortonne JP Genetic disorders o...f pigmentation. Clin Dermatol 23:56-67 (2005) PMID:22150346 (description) Torchia D Mosaic pigmentation disorders and associated syndromes. J Dermatol 39:414-5 (2012) ...

  5. Disease: H00578 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available of cataracts and blue leukocyte inclusion bodies (Doehle-like bodies). Both disorders...iption) Kashtan CE, Segal Y Genetic disorders of glomerular basement membranes. Nephron Clin Pract 118:c9-c1...H, Park YS, Ha IS, Ahn HS, Choi Y, Cheong HI Renal manifestations of patients with MYH9-related disorders. Pediatr Nephrol 26:549-55 (2011) ...

  6. Disease: H00177 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ers RJ, Waterham HR Peroxisomal disorders I: biochemistry and genetics of peroxisome biogenesis disorders. C...lin Genet 67:107-33 (2005) PMID:12740827 Depreter M, Espeel M, Roels F Human peroxisomal disorders. Microsc Res Tech 61:203-23 (2003) ...

  7. Genetics Home Reference: Potocki-Shaffer syndrome

    Science.gov (United States)

    ... Romeike BF, Wuyts W. Proximal chromosome 11p contiguous gene deletion syndrome phenotype: case report and review of the literature. Clin Neuropathol. 2007 Jan-Feb;26(1):1-11. Review. Citation on PubMed Swarr DT, Bloom D, Lewis RA, Elenberg E, Friedman EM, Glotzbach C, Wissman ...

  8. Student's perception towards learning medical sciences: problem based learning versus lecture based learning methods

    Directory of Open Access Journals (Sweden)

    Padmanabha TS.

    2016-04-01

    Conclusions: Students' percieves that the knowledge and understanding could be very easily acquired by PBL over LBL. Students felt Pharmacology should be taught with both ways, initially LBL followed by PBL for better understanding the concepts for clinical application. [Int J Basic Clin Pharmacol 2016; 5(2.000: 411-415

  9. Pattern of anti-diabetic drugs prescribed in a tertiary care hospital of Bangladesh

    Directory of Open Access Journals (Sweden)

    Zuhayer Ahmed

    2016-02-01

    Conclusions: The findings can serve as a guide to choose the formulation and combination of anti-diabetic drugs in this part of the world before developing and marketing any new drug. [Int J Basic Clin Pharmacol 2016; 5(1.000: 6-12

  10. Determinants of durability of first-line antiretroviral therapy regimen and time from first-line failure to second-line antiretroviral therapy initiation

    DEFF Research Database (Denmark)

    Desmonde, Sophie; Eboua, François T; Malateste, Karen;

    2015-01-01

    BACKGROUND: We described reasons for switching to second-line antiretroviral treatment (ART) and time to switch in HIV-infected children failing first-line ART in West Africa. METHODS: We included all children aged 15 years or less, starting ART (at least three drugs) in the paediatric IeDEA clin...

  11. Ibuprofen as a pre-emptive analgesic is as effective as rofecoxib for mandibular third molar surgery

    NARCIS (Netherlands)

    Morse, Zac; Tump, Anna; Kevelham, Ester

    2006-01-01

    The objective of this study was to compare the pre-emptive analgesic effect of rofecoxib, a cyclooxygenase (COX)-2 inhibitor, with a more traditional and commonly used analgesic, ibuprofen, for mandibular third molar surgery, utilizing a prospective, randomized, double-blind, placebo-controlled clin

  12. Brief Report: The Social Responsiveness Scale for Adults (SRS-A)-- Initial Results in a German Cohort

    Science.gov (United States)

    Bolte, Sven

    2012-01-01

    The Social Responsiveness Scale (SRS) is a tool for quantitative autism assessment in children and adolescents. The SRS-A addresses social responsiveness in adulthood. Reliability and validity using the German adaptation of the SRS-A was examined in 20 adults with Autism Spectrum Disorder (ASD), 62 with other mental disorders (CLIN) and 163…

  13. An analytical survey of promotional drug literatures at C. U. Shah Medical College and Hospital, Surendranagar

    Directory of Open Access Journals (Sweden)

    Preeti Narendra Bhatt

    2015-04-01

    Conclusion: The present study showed that pharmaceutical companies do not strictly follow the WHO guidelines and majority of the research were sponsored by companies. Hence, more stringent regulations need to be implemented for the proper promotion and dissemination of information about the new drugs. [Int J Basic Clin Pharmacol 2015; 4(2.000: 325-329

  14. Effect of Tinospora cordifolia as an add - on therapy on the blood glucose levels of patients with Type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Saumya Mishra

    2015-06-01

    Conclusion: The results obtained from the present study conclude that Tc, when given in the form of add-on therapy, was found to be synergistic and effective in the better management of Type 2 diabetes. The drug was well tolerated by the patients and no adverse drug event was recorded. [Int J Basic Clin Pharmacol 2015; 4(3.000: 537-541

  15. Evaluation of hypolipidemic effect of Tinospora cordifolia in cholesterol diet induced hyperlipidemia in rats

    Directory of Open Access Journals (Sweden)

    Sparshadeep E. M.

    2016-08-01

    Conclusions: T.cordifolia has a definite hypolipidemic potential. Although its effectiveness is lesser than rosuvastatin its beneficial role as hypolipidemic agent may be tested in clinical studies. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1286-1292

  16. Student feedback on teaching-learning methodology and evaluation methods in pharmacology

    Directory of Open Access Journals (Sweden)

    Deepika Tikoo

    2015-12-01

    Conclusion: It is important to take regular feedbacks from the students to make the teaching more useful and interesting so that synchronization between teaching-learning, evaluation and assessment can be achieved for improved outcome. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1260-1266

  17. Low-Dose lnterleukin-2 Immunotherapy Does Not Improve Outcome of Patients Age 60 Years and Older with Acute Myeloid Leukemia in First Complete Remission%首次缓解后使用小剂量IL-2免疫治疗不能改善≥60岁老年急性髓性白血病患者预后

    Institute of Scientific and Technical Information of China (English)

    马军; 吴穗晶; 杜欣

    2009-01-01

    @@ 1文献来源 Low-dose Interleukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leukemia in first complete remission: Cancer and Leukemia Group B Study 9720. [J]. J Clin Oncol, 2008,12(26):4934-4939.

  18. 急性髓性白血病的年龄相关危险因素特征及化疗剂量敏感性研究的评价%Assessment of the Age-Related Risk Profile and Chemotherapy Dose Response in Acute Myeloid Leukemia

    Institute of Scientific and Technical Information of China (English)

    杜欣; 郭荣

    2009-01-01

    @@ 1 文献来源 Buchner T, Berdel WE, Haferlach C, et al, Age-related risk profile and chemotherapy dose response in acute myeloid leukemia: A study by the German Acute Myeloid Leukemia Cooperative Group [J]. J Clin Oncol, 2009,27(1):61-69.

  19. Disease: H00212 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00212 Acrodermatitis enteropathica (AEZ) Acrodermatitis enteropathica is an autoso...acterized by intermittent simultaneous occurrence of diarrhea and dermatitis with failure to thrive. Inherit...90629 Maverakis E, Fung MA, Lynch PJ, Draznin M, Michael DJ, Ruben B, Fazel N Acrodermatitis enteropathica a...209 Sehgal VN, Jain S Acrodermatitis enteropathica. Clin Dermatol 18:745-8 (2000) ...

  20. ProbFold

    DEFF Research Database (Denmark)

    Sahoo, Sudhakar; Świtnicki, Michał P; Pedersen, Jakob Skou

    2016-01-01

    code, statically compiled binaries for x86 Linux machines, C ++ programs, example datasets and a tutorial is available from http://moma.ki.au.dk/prj/probfold/Supplementary information: Supplementary data are available at Bioinformatics online. CONTACT: jakob.skou@clin.au.dk....

  1. A prospective study of prescribing pattern of drugs among in-patients of gynaecology department in a tertiary care teaching hospital in South India

    Directory of Open Access Journals (Sweden)

    Bhanu Prakash Kolasani

    2016-08-01

    Conclusions: Antimicrobial agents and vitamins and mineral preparations were the most commonly prescribed drugs. Usage of injections should be reduced as they were relatively more commonly prescribed in our study. Prescription of drugs by generic names must be increased substantially to reduce the economic burden on patients. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1321-1326

  2. Colon and Rectal Cancer Screening (Beyond the Basics)

    Science.gov (United States)

    ... on Colorectal Cancer, and the American College of Radiology. CA Cancer J Clin 2008; 58:130. Whitlock EP, Lin JS, Liles E, et al. Screening for colorectal cancer: a targeted, updated systematic review for the U.S. Preventive Services Task Force. Ann Intern Med 2008; 149:638. ...

  3. Pruritus: An Updated Look at an Old Problem

    OpenAIRE

    Tivoli, Yvette A.; Rubenstein, Richard M.

    2009-01-01

    Pruritus is among the most common dermatological complaints. The authors examine the pathophysiology of itch according to the most common mediators uncovered by researchers. They also discuss the encompassing etiologies, which include dermatological, psychological, and systemic causes. Finally, they discuss the diagnostic approach and the latest, most appropriate treatment options. (J Clin Aesthetic Dermatol. 2009;2(7):30–36.)

  4. LOCOMOTIVE SYSTEM

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    2004137 Distant bone metastasis of osteosarcoma: a report of 5 cases. XING Ruwei (邢汝维), et al. Dept Bone & Soft Tissue Tumour, Tianjin Cancer Hosp, Tianjin 300060. Chin J Clin Oncol 2003; 30(11) :786-788.Objective: To explore the clinical manifestation, diagnosis , treatment and prognosis of distant bone metastasis of osteosarcoma. Methods: A retrospective analysis and study on

  5. 75 FR 4569 - Government-Owned Inventions; Availability for Licensing

    Science.gov (United States)

    2010-01-28

    ... encoded proteins. These results provide a molecular classification system for thyroid tumors and this in... distinguishing benign and malignant thyroid tumors solely on cellular features. Since most nodules usually end up... expressed in benign versus malignant thyroid tumors. Clin Cancer Res. 2008 Jun 1;14(11):3327-3337. 2....

  6. Examinations and curriculum in medical education and learning-assessment relations

    OpenAIRE

    Rahman YAVUZ; TONTUŞ, Hacı Ömer

    2014-01-01

    In recent times, the increasingly growing developments contribute to be configured to curriculum and examinations. Even though the curriculum planning and development are extremely important: it should be noted that students’ examination anxiety. We may consider it as the relationship among the student-tutorials-education program. J. Exp. Clin. Med., 2014; 31:1-5

  7. 放化疗治疗局部进展期胰腺癌的定性系统评价%Chemoradiotherapy in the Management of Locally Advanced Pancreatic Carcinoma: A Qualitative Systematic Review

    Institute of Scientific and Technical Information of China (English)

    李伟雄; 黄凌

    2010-01-01

    @@ 1 文献来源 Huguet F,Girard N,Guerche CS,et al.Chemoradiotherapy in the management of locally advanced pancreatic carcinoma: A qualitative systematic review[J].J Clin Oncol,2009,27(13):2269-2277

  8. Disease: H01304 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters. J Clin Invest 118:3881-92 (2008) ... ...alczuk S, Ng C, Vanslambrouck JM, Rodgers H, Auray-Blais C, Cavanaugh JA, Broer A, Rasko JE Iminoglycinuria

  9. Genotoxic and histotoxic effects of air pollutants at a benzene station on albino rats

    Directory of Open Access Journals (Sweden)

    Mohamed Abousalem

    2014-02-01

    Conclusions: The findings of the present study indicated that benzene exposure may lead to toxic effects including, genotoxicities and histotoxicities. In order to minimize the predicted toxic effect of occupational exposure to benzene the strict protective measures should be put in consideration. [Int J Basic Clin Pharmacol 2014; 3(1.000: 144-150

  10. Population pharmacokinetic modelling to assess the impact of CYP2D6 and CYP3A metabolic phenotypes on the pharmacokinetics of tamoxifen and endoxifen

    NARCIS (Netherlands)

    ter Heine, Rob; Binkhorst, Lisette; de Graan, Anne Joy M; de Bruijn, Peter; Beijnen, Jos H; Mathijssen, Ron H J; Huitema, Alwin D R

    2014-01-01

    AIMS: Tamoxifen is considered a pro-drug of its active metabolite endoxifen. The major metabolic enzymes involved in endoxifen formation are CYP2D6 and CYP3A. There is considerable evidence that variability in activity of these enzymes influences endoxifen exposure and thereby may influence the clin

  11. Recent advances in the diagnosis of Cushing’s syndrome in dogs

    NARCIS (Netherlands)

    Kooistra, H.S.; Galac, S.

    2010-01-01

    Vet Clin North Am Small Anim Pract. 2010 Mar;40(2):259-67. Recent advances in the diagnosis of Cushing's syndrome in dogs. Kooistra HS, Galac S. Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands. H

  12. Drug utilization study on antidiabetic medications at SIMS-Shimoga a tertiary care hospital

    Directory of Open Access Journals (Sweden)

    H. Vedavathi

    2015-10-01

    Conclusion: Metformin was the oral hypoglycemic agents, which was the most frequent prescribed as was insulin and its analogs. These drugs being essential in the treatment of diabetic patients should be made available to patients all the time. [Int J Basic Clin Pharmacol 2015; 4(5.000: 946-950

  13. Can A Traumatic Bladder Injury be Fatal: A Case Series of 8 Patients

    Directory of Open Access Journals (Sweden)

    Suhail Yaqoob Hakim

    2012-04-01

    Conclusions: Early detection and early repair is the key to success in a bladder injury. Bilateral percutaneous nephrostomy and re-exploration with bladder drainage does not help once sepsis sets in. [Arch Clin Exp Surg 2012; 1(2.000: 102-104

  14. A multicentre pharmacoepidemiological study of dermatological disorders in Wardha district

    Directory of Open Access Journals (Sweden)

    Anita H. Yuwnate

    2013-12-01

    Conclusions: The prevalence of dermatological disorders is 8.19 %. Younger age group (21-40 yrs and Females is most affected by dermatological disorders. The commonest dermatological disorder is Acne and in prescription analysis, antifungals are most commonly prescribed. [Int J Basic Clin Pharmacol 2013; 2(6.000: 751-756

  15. An adaptive radiotherapy planning strategy for bladder cancer using deformation vector fields

    International Nuclear Information System (INIS)

    Purpose: Adaptive radiotherapy (ART) has considerable potential in treatment of bladder cancer due to large inter-fractional changes in shape and size of the target. The aim of this study was to compare our clinically applied method for plan library creation that involves manual bladder delineations (Clin-ART) with a method using the deformation vector fields (DVFs) resulting from intensity-based deformable image registrations (DVF-based ART). Materials and methods: The study included thirteen patients with urinary bladder cancer who had daily cone beam CTs (CBCTs) acquired for set-up. In both ART strategies investigated, three plan selection volumes were generated using the CBCTs from the first four fractions; in Clin-ART boolean combinations of delineated bladders were used, while the DVF-based strategy applied combinations of the mean and standard deviation of patient-specific DVFs. The volume ratios (VRs) of the course-averaged PTV for the two ART strategies relative the non-adaptive PTV were calculated. Results: Both Clin-ART and DVF-based ART considerably reduced the course-averaged PTV, compared to non-adaptive RT. The VR for DVF-based ART was lower than for Clin-ART (0.65 vs. 0.73; p < 0.01). Conclusions: DVF-based ART for bladder irradiation has a considerable normal tissue sparing potential surpassing our already highly conformal clinically applied ART strategy

  16. Medication errors in outpatient setting of a tertiary care hospital: classification and root cause analysis

    Directory of Open Access Journals (Sweden)

    Sunil Basukala

    2015-12-01

    Conclusions: Learning more about medication errors may enhance health care professionals' ability to provide safe care to their patients. Hence, A focus on easy-to-use and inexpensive techniques for medication error reduction should be used to have the greatest impact. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1235-1240

  17. Are patient decision aids the best way to improve clinical decision making? Report of the IPDAS Symposium.

    NARCIS (Netherlands)

    Holmes-Rovner, M.; Nelson, W.L.; Pignone, M.; Elwyn, G.; Rovner, D.; O'Connor, A.M.; Coulter, A.; Correa-de-Araujo, R.

    2007-01-01

    This article reports on the International Patient Decision Aid Standards Symposium held in 2006 at the annual meeting of the Society for Medical Decision Making in Cambridge, Massachusetts. The symposium featured a debate regarding the proposition that "decision aids are the best way to improve clin

  18. Drug utilization pattern in geriatric inpatients of medicine department in a Tertiary Care Teaching Hospital

    Directory of Open Access Journals (Sweden)

    Swapna R. Nayaka

    2015-06-01

    Conclusion: Thus, irrational prescribing and polypharmacy were prevalent among elderly. Drug utilization data can help in assessing the quality of care given to the geriatric patients and promote rational use of medicines. [Int J Basic Clin Pharmacol 2015; 4(3.000: 568-573

  19. A study on knowledge, attitude and practice on blood donation among medical students in a tertiary care teaching hospital, Chennai, Tamil Nadu, India

    Directory of Open Access Journals (Sweden)

    Jeya S. Ponmari

    2016-06-01

    Conclusions: The present study shows second MBBS students participated in the study has adequate knowledge and attitude. The practice of blood donation is also good and further can be improved by educational programmes. [Int J Basic Clin Pharmacol 2016; 5(3.000: 802-804

  20. Digital protocol for reference-based guided surgery and immediate loading: a prospective clinical study

    NARCIS (Netherlands)

    A. Tahmaseb; R. de Clerck; I. Aartman; D. Wismeijer

    2012-01-01

    PURPOSE: To evaluate the performance of a computer-aided three-dimensional planning protocol in combination with previously inserted reference mini-implants and CAD/CAM technology to restore completely edentulous patients. The study evaluated implant and superstructure survival in a prospective clin

  1. Nomograms to Predict Pathologic Complete Response and Metastasis-Free Survival after Preoperative Chemotherapy for Breast Cancer%采用列线图对乳腺癌进行新辅助治疗后病理完全缓解及无复发生存的预测

    Institute of Scientific and Technical Information of China (English)

    王永胜; 廖宁

    2007-01-01

    @@ 1文献类型 治疗. 2证据水平 2b. 3文献来源 Rouzier R, Pusztai L, Delaloge S, et al.Nomograms to predict pathologic complete response and metastasis-free survival after preoperative chemotherapy for breast cancer [J]. J Clin Oncol,2005,23(33): 8331-8339.

  2. A study on the drug prescribing pattern in acute, recurrent and chronic pharyngitis at a tertiary care hospital

    Directory of Open Access Journals (Sweden)

    Deepa Ranabovi

    2016-08-01

    Conclusions: Acute, recurrent and chronic bacterial pharyngitis can be effectively treated by empirical use of various antimicrobials. Co-amoxiclav can be considered as the mainstay/primary option because of the proven efficacy, good tolerability and low cost. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1494-1498

  3. Chemical composition and antimicrobial activities of leaves of sweet basil (Ocimum basilicum L. herb

    Directory of Open Access Journals (Sweden)

    Hadush Gebrehiwot

    2015-10-01

    Conclusion: So, the study has showed that the observed antimicrobial effect of O. basilicum essential oil on the bacterial and fungal isolate, though in vitro appear interesting and promising. So, emphasize have to made on the antimicrobial activities of the plant during the time of drug extraction. [Int J Basic Clin Pharmacol 2015; 4(5.000: 869-875

  4. Evaluation of burn wound healing property of ocimum sanctum by monitoring of period of re-epithelization in rabbits

    Directory of Open Access Journals (Sweden)

    Vaibhav K. Gupta

    2016-02-01

    Conclusions: Group treated with ointment silver sulfadiazine + O. sanctum showed minimum re-epithelization period. So, the most effective treatment for burn wound healing in this study was ointment silver sulfadiazine + O. sanctum. [Int J Basic Clin Pharmacol 2016; 5(1.000: 146-148

  5. Restricted feeding of a high-fat diet reduces spontaneous metastases of Lewis lung carcinoma in C57BL/6 mice

    Science.gov (United States)

    Obesity is a risk factor for cancer. We previously reported that consumption of a high-fat diet enhances metastasis in mice (Yan, Clin Exp Metastasis 2010). The present study investigated the effects of restricted feeding of a high-fat diet on spontaneous metastasis of Lewis lung carcinoma (LLC) i...

  6. Efficacy of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Northeast Ethiopia

    Directory of Open Access Journals (Sweden)

    Assefa Mulu

    2015-06-01

    Conclusions: In general, this study discovered good clinical and parasitological response of P. falciparum to artemether/lumefantrine. Further polymeric chain reaction and plasma drug concentration based effectiveness study of artemether/lumefantrine should be conducted throughout the country. [Int J Basic Clin Pharmacol 2015; 4(3.000: 492-496

  7. Oral clonidine: a simple yet effective and safe premedicant for hemodynamic stability during laparoscopic surgery and a calm post-operative period

    Directory of Open Access Journals (Sweden)

    Ketaki Marodkar

    2016-04-01

    Conclusions: Oral clonidine in the present dose is able to maintain stable intra-operative haemodynamics and achieve a calm post-operative period during laparoscopic surgeries in ASA I/II patients. [Int J Basic Clin Pharmacol 2016; 5(2.000: 293-299

  8. Hepatitis

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    2008449 A cross-sectional survey of occult hepatitis B virus infection in HIV-infected patients. MA Jianxin(马建新), et al.Dept Infect Dis, Shanghai Public Health Clin Center, Shanghai 201508. Chin J Intern Med 2008;47(7):574-577. Objective To assess the prevalence of occult HBV infection in HIV-infected patients.

  9. Prescribing pattern of antidepressants in psychiatric unit of a tertiary care hospital

    Directory of Open Access Journals (Sweden)

    E. Avanthi

    2014-08-01

    Conclusions: Depression is more commonly seen in married people predominantly in females and housewives. Fluoxetine is more commonly used followed by escitalopram. Selective serotonin reuptake inhibitors are preferred over other antidepressant because of their relative lesser side effects. [Int J Basic Clin Pharmacol 2014; 3(4.000: 667-670

  10. Adverse effects including sexual problems associated with the use of selective serotonin reuptake inhibitors in a tertiary care center of Eastern Nepal

    Directory of Open Access Journals (Sweden)

    Bhawesh Koirala

    2015-08-01

    Conclusion: Adverse effect (irrespective of severity was commonly seen with SSRI use. Common adverse effects seen among remitted subjects were weight gain, dryness of mouth, headache, dizziness, paresthesia, etc. SD was other important side effect. [Int J Basic Clin Pharmacol 2015; 4(4.000: 651-656

  11. Role of pharmaco-epidemiology in psychopharmacology: a study in psychiatric out-patient department of a tertiary care teaching hospital at Dehradun, Uttarakhand

    Directory of Open Access Journals (Sweden)

    Shaktibala Dutta

    2014-08-01

    Conclusions: Anti-A drugs were the most commonly prescribed drugs followed by anti-Ds, anti-Ps and anti-Es respectively. Rational prescribing requires further consideration with special reference to polypharmacy and providing feedback to the physicians. [Int J Basic Clin Pharmacol 2014; 3(4.000: 637-643

  12. A cross-sectional comparative study to determine the factors contributing to the academic performance of the high performers and low performers in 2nd year medical students

    Directory of Open Access Journals (Sweden)

    Yogeeta Sushant Walke

    2015-12-01

    Conclusion: Through our study, we identified important factors contributing to high performance in academics, and we concluded that students should incorporate all the factors in a well-coordinated manner rather than focusing on any single factor. If executed, appropriately it will definitely upgrade their academic performance and prevent undesirable failures. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1072-1079

  13. An epidemiological survey to assess the clinical use of cephalosporins in community-acquired respiratory tract infections

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    Vikram Sobti

    2015-06-01

    Conclusion: In-clinic use of cefpodoxime as monotherapy is preferred in upper respiratory tract infections. However, clinicians recommend a combination therapy of cefpodoxime and levofloxacin in lower respiratory tract infections. [Int J Basic Clin Pharmacol 2015; 4(3.000: 547-550

  14. Post graduate survey and evaluation of role of animal experimentation, status and relevance of current syllabus, and challenges for alignment with requirements of the pharmaceutical industry

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    Prashant Dass

    2016-06-01

    Conclusions: We conclude that the importance of AE in pharmacology is irrefutable, although advent of alternatives is the direction to be headed in. The curriculum is archaic at times, thus warrants changes. Preparedness for pharmaceutical industry is also low and needs to be addressed. [Int J Basic Clin Pharmacol 2016; 5(3.000: 935-941

  15. To study the efficacy and tolerability of fenugreek seed powder as add-on therapy with metformin in patients of type-2 diabetes mellitus

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    Manmeet Kaur

    2016-04-01

    Conclusions: This study shows the beneficial effects of fenugreek seeds on glycemic profile in patients of Type 2 DM and can be used as an add-on therapy with metformin in management of Type 2 DM. [Int J Basic Clin Pharmacol 2016; 5(2.000: 378-383

  16. Genetics Home Reference: type 1 diabetes

    Science.gov (United States)

    ... JM, Mayer-Davis EJ. Epidemiology of type 1 diabetes. Endocrinol Metab Clin North Am. 2010 Sep;39(3):481-97. doi: 10.1016/j.ecl.2010.05.011. Review. Citation on PubMed or Free article on PubMed ... G. Insights into type 1 diabetes provided by genetic analyses. Curr Opin Endocrinol Diabetes ...

  17. Myocardial salvaging effects and mechanisms of metformin in experimental diabetes

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    Manjusha K. Borde

    2016-04-01

    Conclusions: The present study concluded that Metformin at 100 mg/kg demonstrated myocardial salvaging effects in type II diabetic rats challenged with experimental Myocardial infarction. The antioxidant, hypoglycemic, hypolipidemic and anti-inflammatory effects of Metformin may contribute to its beneficial effects. [Int J Basic Clin Pharmacol 2016; 5(2.000: 341-349

  18. Pattern of prescription and drug use in psychiatry out patient department of private practitioners of Central India

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    Chetna A. Shamkuwar

    2013-12-01

    Conclusions: Anti-anxiety drug (benzodiazepines was the most frequently prescribed class of psychotropic drugs in various psychiatry disorders. The prescribing prevalence of Alprazolam with different brand names was more than that of other benzodiazepines. The combination of different psychotropic drugs were also prescribed. [Int J Basic Clin Pharmacol 2013; 2(6.000: 777-782

  19. A study of potential drug-drug interactions among critically ill patients at a tertiary care hospital

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    Manjeeta Gupta

    2016-08-01

    Conclusions: The present study showed high concomitant administration of potentially interacting drugs. The prevalence confirmed the association of age and polypharmacy. Vigilant prescribing approach is needed to prevent hazardous outcomes of pDDI. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1281-1285

  20. Study of patterns of prescribing antibiotics in geriatric patients admitted to the medical wards in a tertiary care hospital

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    Ankita Bist

    2016-02-01

    Conclusions: Polypharmacy is commonly observed practice in geriatric patients. Apart from increasing the cost of treatment it also promotes irrational prescription of drugs. Most of the prescriptions were in adherence with the WHO's Essential Medicine List but antibiotics were mainly prescribed empirically. [Int J Basic Clin Pharmacol 2016; 5(1.000: 155-158

  1. Trends in drug usage among elderly with cardiovascular diseases

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    Rajeshwari Shastry

    2014-08-01

    Conclusion: Among the antihypertensive groups CCBs were the most commonly used followed by BB, ARBs and ACEIs. Among these antihypertensive agents amlodipine, losartan, atenolol and enalapril were most commonly used. Commonly used antidiabetic agents were metformin and glimepiride. [Int J Basic Clin Pharmacol 2014; 3(4.000: 723-725

  2. A cross-sectional study to assess the rationality of fixed dose combinations prescribed in geriatric patients in a tertiary care hospital

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    Ahish Dakappa

    2016-08-01

    Conclusions: The prescription rate of irrational FDCs is very high in our hospital. There is a need to educate physicians regarding consequences of use of such irrational FDCs. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1441-1447

  3. Prescribing pattern of antimicrobials in various clinical departments of a tertiary care hospital

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    Rohith V.

    2016-04-01

    Conclusions: It was found that penicillins were the most commonly prescribed group of antimicrobials, significantly less number of antimicrobials were prescribed by generic name, 80.18% of antimicrobials were prescribed from NLEM and tablets/ capsules were the most common dosage forms. [Int J Basic Clin Pharmacol 2016; 5(2.000: 402-405

  4. The correlation between cognitive function and cerebral white matter lesions/insulin resistance in patients with lacunar infarction:a clinical study of 184 cases

    Institute of Scientific and Technical Information of China (English)

    张琼予

    2013-01-01

    Objective To investigate the correlation between cognitive function and cerebral white matter lesions(WML)/insulin resistance(IR) in patients with stroke.Methods Between May 2011 and October 2011,the clin-ical data of 184 in-patients with lacunar infarction were

  5. Ondansetron versus palonosetron: a comparative study on efficacy and safety in prevention of postoperative nausea and vomiting

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    Bhanu Prakash G.

    2016-08-01

    Conclusions: Our study concludes that the antiemetic efficacy is comparable for both ondansetron and palonosetron in the given doses in preventing PONV and none is superior. Both the study drugs had almost the same adverse effect profile. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1269-1274

  6. Study of potential drug-drug interactions between benzodiazepines and four commonly used antiepileptic drugs in mice

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    Kartik N. Shah

    2014-10-01

    Conclusion: Clonazepam potentiates the action of all the four anti-epileptics while diazepam potentiates only phenytoin and CBZ against MES seizures. Clonazepam but not diazepam potentiates the action of sodium valproate against PTZ seizures. [Int J Basic Clin Pharmacol 2014; 3(5.000: 830-835

  7. Study of prescription pattern in emergency psychiatry in a tertiary care academic hospital of a developing country: a retrospective study

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    Kamal Nath

    2016-02-01

    Conclusions: Use of parenteral typical antipsychotic was found to be much higher, than expected. For the benefit of the mass, supply of cost effective parenteral atypical antipsychotics is the need of the hour in this part of the world. [Int J Basic Clin Pharmacol 2016; 5(1.000: 45-54

  8. A very rare case of HPV-53-related cervical cancer, in a 79-year-old woman with a previous history of negative Pap cytology [corrigendum

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    Zappacosta R

    2014-12-01

    Full Text Available Zappacosta R, Lattanzio G, Viola P, Ianieri MM, Gatta DMP, Rosini S. Clin Interv Aging. 2014;9:683–688.On page 686, Figure 3 originally contained one panel and incorrect heading and notes. The authors have provided a new Figure 3 and a new legend.Read the original article 

  9. Evaluation of nootropic activity of Curcuma longa leaves in diazepam and scopolamine-induced amnesic mice and rats

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    Nayana Reddy

    2015-08-01

    Conclusion: This could be by inhibiting the levels of cholinesterase concentration of enzyme and thereby increasing the concentration of acetylcholine level in brain and improving cognition-memory performance. [Int J Basic Clin Pharmacol 2015; 4(4.000: 714-719

  10. Effect of bevacizumab, which remain after withdrawal of the first dose/s from a single-use vial on diabetic macular edema

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    Mehmet Demir

    2015-02-01

    Conclusion: Bevacizumab which remain in the single use vial after first dose/s is safe and effective for treatment of DME. These results are useful for poor countries. [Int J Basic Clin Pharmacol 2015; 4(1.000: 159-163

  11. Use of clopidogrel and calcium channel blockers and risk of major adverse cardiovascular events

    DEFF Research Database (Denmark)

    Schmidt, Morten; Johansen, Martin B; Robertson, Douglas J;

    2012-01-01

    Eur J Clin Invest 2011 ABSTRACT: Background  The CYP3A4 inhibition by calcium channel blockers (CCBs) may attenuate the effectiveness of clopidogrel. Using time-varying drug exposure ascertainment, we examined whether CCB use modified the association between clopidogrel use and major adverse...

  12. Understanding the degree of awareness among medical professionals regarding the ethics of pharmaceutical marketing activities in context of revised medical council of India code of ethics

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    Renuka H. Munshi

    2016-04-01

    Conclusions: Most physicians do maintain a code of ethics with regards to accepting gifts and they felt that inexpensive gifts do not influence clinical judgment. Consultants were of the view that amended MCI code of ethics would not affect their clinical practice significantly. [Int J Basic Clin Pharmacol 2016; 5(2.000: 263-268

  13. A comparative study of effect on reducing pain, inflammation and side effect of combination of enzymes (bacterial proteases, papain, bromelain, vitamin C and rutin versus conventional non-steroidal anti-inflammatory drugs (diclofenac in patients of closed fracture lower end radius coming at orthopaedic department of a tertiary care hospital

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    Tejas A. Acharya

    2016-06-01

    Conclusions: Diclofenac was better in reducing pain, while combination of enzymes used in the study was better in reducing oedema. Combination of the enzymes used in this study is safer than diclofenac in cases of the closed fracture lower end radius. [Int J Basic Clin Pharmacol 2016; 5(3.000: 1017-1021

  14. Knowledge, attitude and practice of pharmacovigilance among private healthcare professionals of Rajkot city

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    Bharti N. Karelia

    2014-02-01

    Conclusions: There was a great need to create awareness among the private doctors to improve the reporting of ADRs. Even though ADR reporting make compulsory by doctors unless there is no strict government rules and regulation success of pharmacovigilance programme is questionable. [Int J Basic Clin Pharmacol 2014; 3(1.000: 50-53

  15. Comparative assessment of efficacy of lignocaine (1.5 mg/kg, esmolol (300 and micro;g/kg, and dexmedetomidine (0.5 and micro;g/kg in minimizing the pressor response to laryngoscopy and intubation

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    Prashant Dass

    2015-04-01

    Conclusion: Dexmedetomidine 0.5 and micro;g/kg has manifested to maintain hemodynamic stability associated with intubation and hence may prove beneficial for cardiac patients where the stress response to laryngoscopy and intubation is highly undesirable. [Int J Basic Clin Pharmacol 2015; 4(2.000: 306-311

  16. Prescribing pattern in ophthalmological outpatient department of a tertiary care teaching hospital in Dehradun, Uttarakhand: a pharmaco-epidemiological study

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    S. B. Dutta

    2014-06-01

    Conclusion: Topical antimicrobial agents are the most commonly used drugs in ophthalmic OPD in our setup; the most common FDCs prescribed were antimicrobials with steroids, the other commonly used drugs were analgesics, CMC and anti-allergic drugs. [Int J Basic Clin Pharmacol 2014; 3(3.000: 547-552

  17. Disease: H01087 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 04) PMID:17402277 (description) Karanis P, Kourenti C, Smith H Waterborne transmission of protozoa...tozoa as causal agents of waterborne zoonotic disease. Vet Parasitol 126:91-120 (20...m coli. Clin Microbiol Rev 21:626-38 (2008) PMID:15567581 (descrition, env_factor) Schuster FL, Visvesvara GS Amebae and ciliated pro

  18. Pharmacoeconomical evaluation of hypertension with diabetes mellitus in a teaching hospital in urban Bangalore

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    Rajat Rana

    2016-04-01

    Conclusions: This study concludes that the there is a huge economic burden on the patient from the lower income group. Medication cost and diagnostic cost are among the major factors that accounts for the total health care cost. [Int J Basic Clin Pharmacol 2016; 5(2.000: 473-477

  19. Atypical pneumonia

    Science.gov (United States)

    ... America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis . 2007;44:S27-S72. PMID: 17278083 ... by: Denis Hadjiliadis, MD, Associate Professor of Medicine, Pulmonary, Allergy and Critical Care, Perelman ...

  20. Lead acetate toxicity on glucose level and liver enzymes ameliorated by camel's milk in wistar albino rat

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    Marwan M. Draid

    2016-06-01

    Conclusions: The ability of camel milk to reduce lead toxicity may relate to its antioxidant actions or enhancing, the metal chelating action. In conclusion, Supplementation of daily diets with camel milk may be recommended to improve the body in case of lead contamination. [Int J Basic Clin Pharmacol 2016; 5(3.000: 1125-1130