WorldWideScience

Sample records for clin dev prgms

  1. Haiti DevResults

    Data.gov (United States)

    US Agency for International Development — DevResults is a web-based portfolio management system that tracks program data for the Haiti Mission that was awarded in April of 2013. (The Mozambique and/or...

  2. DevOops Redux

    CERN Document Server

    CERN. Geneva; Johnson, Ken

    2017-01-01

    DevOps toolchains are transforming Modern IT, but hackers can undermine their benefits through poorly implemented or vulnerable DevOps tools. Chris Gates and Ken Johnson will share their collaborative attack research into the technology driving DevOps. They will share an attacker?s perspective on exploiting DevOps organizations and the countermeasures these organizations should employ. About the speakers Ken Johnson, CTO of nVisium, has been hacking web applications professionally for 8 years. Ken is both a breaker and builder and currently leads the nVisium product team. Previously, Ken has spoken at DerbyCon, AppSec USA, AppSec DC, AppSec California, DevOpsDays DC, LASCON, RubyNation, and numerous Ruby, OWASP, and AWS events. Ken is currently investing his time between OWASP’s Railsgoat, Elxir and Go, as well as all aspects of AWS offerings. Chris Gates has extensive experience in network and web application penetration testing, Red Teaming and Purple Teaming. Chris is currently learning to be ...

  3. Service Provider DevOps

    OpenAIRE

    John, Wolfgang; Marchetto, Guido; Németh, Felicián; Sköldström, Pontus; Steinert, Rebecca; Meirosu, Catalin; Papafili, Ioanna; Pentikousis, Kostas

    2017-01-01

    Although there is consensus that software defined networking and network functions virtualization overhaul service provisioning and deployment, the community still lacks a definite answer on how carrier-grade operations praxis needs to evolve. This article presents what lies beyond the first evolutionary steps in network management, identifies the challenges in service verification, observability, and troubleshooting, and explains how to address them using our Service Provider DevOps (SP-DevO...

  4. 玩转DevOps

    Institute of Scientific and Technical Information of China (English)

    韩拓

    2013-01-01

    伴随着互联网时代的真正到来和云计算市场的兴起,DevOps这个词进入了我们的视野。我们可以认为DevOps是一组方法论的统称,它扩大了开发和运维的外延,促进开发、运维、质量保障、运营等各部门的协调与整合,定义了简明、自动化的流程,使我们可以承担更快的变更、更小的风险,

  5. Computational Linguistics in the Netherlands 2007 : Selected papers from the eighteenth CLIN meeting (CLIN 2007)

    NARCIS (Netherlands)

    Verberne, Suzan; Halteren, Hans van; Coppen, Peter-Arno

    2008-01-01

    This book contains a selection of the papers presented at the eighteenth edition of the Computational Linguistics in the Netherlands (CLIN) conference. The 18th CLIN edition took place at the Radboud University Nijmegen on December 7th, 2007. It was organized by the Language and Speech group at the

  6. Final Service Provider DevOps concept and evaluation

    OpenAIRE

    Marchetto, Guido; Sisto, Riccardo; John, Wolfgang; Sköldström, Pontus; Pechenot, Bertrand; Németh, Felicián; Pelle, István; Kim, Juhoon; Cai, Xuejun; Fu, Chunyan; Meirosu, Catalin; Pentikousis, Kostas; Sharma, Sachin; Papafili, Ioanna; Spinoso, Serena

    2016-01-01

    This report presents the results of the UNIFY Service Provider DevOps activities. First, we present the final definition and assessment of the concept. SP-DevOps is realized by a combination of various functional components facilitating integrated service verification, efficient and programmable observability, and automated troubleshooting processes. Our assessment shows that SP-DevOps can help providers to reach a medium level of DevOps maturity and allows significant reduction in OPEX. Seco...

  7. Management Challenges for DevOps Adoption within UK SMEs

    OpenAIRE

    Jones, Stephen; Noppen, Joost; Lettice, Fiona

    2016-01-01

    The DevOps phenomenon is gathering pace as more UK organisations seek to leverage the benefits it can potentially bring to software engineering functions. However substantial organisational change is inherent to adopting DevOps, especially where there are prior and established methods. As part of a wider piece of doctoral research investigating the management challenges of DevOps adoption, we present early findings of a six month qualitative diary study following the adoption of DevOps within...

  8. 赢在 DevOps

    Institute of Scientific and Technical Information of China (English)

    薛帆

    2015-01-01

    在云计算、大数据等技术颠覆性趋势继续在应用经济下发挥作用的同时,DevOps也已经稳健地在业务思维方式中占有一席之地,2015年对于很多企业来说是DevOps之路的第一步,那么,各大企业应如何更好地迎接这关键性的时刻呢?为此,本刊记者有幸采访到了CA Technologies亚太及日本地区应用交付副总裁Ashok Vasan先生。

  9. From Domain Specific Languages to DEVS Components: Application to Cognitive M&S

    Science.gov (United States)

    2011-04-01

    DEVS/SOA framework [11] is analogous to other DEVS distributed simulation frameworks like DEVS/HLA, DEVS/RMI and DEVS/ CORBA [12-16] and uses web...W, " CORBA -Based Multi-threaded Distributed Simulation of Hierarchical DEVS Models: Transforming Model Structure into a Non-hierarchical One

  10. Dev sublingual epidermoid kist: Olgu sunumu

    Directory of Open Access Journals (Sweden)

    Salim Yüce

    2013-06-01

    Full Text Available Epidermoid ve dermoid kistler vücudun çeşitli bölgelerinde görülebilen benign karakterli lezyonlardır. Bu kistler oral kavitede %1,6 oranında görülürler ve oral kavite kistleri arasında oldukça nadir bir yer tutarlar. Ender görülen bu patolojilerden, sublingual yerleşimli dev epidermoid kist tanılı bir olgumuzu literatür bilgileri eşliğinde sunduk.

  11. Software Development with DevOps

    OpenAIRE

    Kristinsson, Rögnvaldur

    2015-01-01

    The goal of the study was to introduce DevOps in software development, its methods and approaches to software development. I was introduced to the subject by one of my teach-ers, which let me into further studies and researched on the subject and finally choosing it for the study. The subject was completely new to me when I started the study which I found inspirational as I was learning a new and an interesting subject on a daily basis dur-ing the process of writing the study. The materia...

  12. Dev konka bülloza piyoseli

    Directory of Open Access Journals (Sweden)

    Cüneyt Kucur

    2014-06-01

    Full Text Available Konka bülloza,havalanmış (pnömatize veya içinde bir havalı hücre bulunan orta konka için kullanılan bir terimdir. Genellikle asemptomatik olmakla birlikte pnömatizasyonun büyüklüğüne ve nazal septumla olan ilişkisine göre burun tıkanıklığı semptomları verebilir ve ostiomeatal komplekse bası oluşturmakta ise tikanmasina neden olarak sinüzite yol açabilir. Piyosele dönüşmesi nadirdir. Dev konka bülloza endoskopİk muayenede orta konkanin genişlemiş bir bölümü olarak görülür. Konka bülloza kesin tanısı paranazal sinus bilgisayarlı tomografisi (BT ile koyulur. Tedavisinde endoskopik olarak orta konkanın lateral parsiyel rezeksiyonu yeterli ve minimal invazif bir yöntemdir. Bu yazıda sağ nazal pasajı tamamen tıkayan ve nazal vestibüle kadar uzanım gösteren ve aynı tarafta sinüzite yol açan tek taraflı dev konka bülloza piyoseli olgusu sunulmuştur.

  13. 破解DevOps的五大迷思

    Institute of Scientific and Technical Information of China (English)

    Sumal Karunanayake

    2014-01-01

    DevOps集开发、测试、部署和运营为一体,并迅速成为加速应用交付的典型技术。如今,业务成功更加依赖于高质量软件服务,因此DevOps的影响也日益显著。同其他新技术一样,DevOps的出现也激起了许多讨论。在深入理解DevOps之前。

  14. Performance-oriented DevOps: A Research Agenda

    OpenAIRE

    Brunnert, Andreas; van Hoorn, Andre; Willnecker, Felix; Danciu, Alexandru; Hasselbring, Wilhelm; Heger, Christoph; Herbst, Nikolas; Jamshidi, Pooyan; Jung, Reiner; von Kistowski, Joakim; Koziolek, Anne; Kroß, Johannes; Spinner, Simon; Vögele, Christian; Walter, Jürgen

    2015-01-01

    DevOps is a trend towards a tighter integration between development (Dev) and operations (Ops) teams. The need for such an integration is driven by the requirement to continuously adapt enterprise applications (EAs) to changes in the business environment. As of today, DevOps concepts have been primarily introduced to ensure a constant flow of features and bug fixes into new releases from a functional perspective. In order to integrate a non-functional perspective into these DevOps concepts th...

  15. Continuous Integration, Deployment and Testing in DevOps Environment

    OpenAIRE

    Amaradri, Anand Srivatsav; Nutalapati, Swetha Bindu

    2016-01-01

    Context. Owing to a multitude of factors like rapid changes in technology, market needs, and business competitiveness, software companies these days are facing pressure to deliver software rapidly and on a frequent basis. For frequent and faster delivery, companies should be lean and agile in all phases of the software development life cycle. An approach called DevOps, which is based on agile principles has come into play. DevOps bridges the gap between development and operations teams and fa...

  16. DevOps:推倒隔阂之墙

    Institute of Scientific and Technical Information of China (English)

    张贝贝

    2013-01-01

    DevOps是一个融合词,即把开发(Develop)和运维(Operation)合在一起,表面上看,这个词合起来很容易,但实际操作的过程并不容易。因为在开发和运维中间始终有堵墙,DevOps要做的就是将其推倒。

  17. Service Provider DevOps network capabilities and tools

    OpenAIRE

    Steinert, Rebecca; John, Wolfgang; Sköldström, Pontus; Pechenot, Bertrand; Gulyás, András; Pelle, István; Lévai, Tamás; Németh, Felicián; Kim, Juhoon; Meirosu, Catalin; Cai, Xuejun; Fu, Chunyan; Pentikousis, Kostas; Sharma, Sachin; Papafili, Ioanna

    2015-01-01

    This report provides an understanding of how the UNIFY Service Provider (SP)-DevOps concept can be applied and integrated with a combined cloud and transport network NFV architecture. Specifically, the report contains technical descriptions of a set of novel SP-DevOps tools and support functions that facilitate observability, troubleshooting, verification, and VNF development processes. The tools and support functions are described in detail together with their architectural mapping, giving a...

  18. DEVS Models of Palletized Ground Stacking in Storeyed Grain Warehouse

    Directory of Open Access Journals (Sweden)

    Hou Shu-Yi

    2016-01-01

    Full Text Available Processed grain stored in storeyed warehouse is generally stacked on the ground without pallets. However, in order to improve the storing way, we developed a new stacking method, palletized ground stacking. Simulation should be used to present this new storing way. DEVS provides a formalized way to describe the system model. In this paper, DEVS models of palletized ground stacking in storeyed grain warehouse are given and a simulation model is developed by AutoMod.

  19. Co-expression of DevR and DevR(N-Aph proteins is associated with hypoxic adaptation defect and virulence attenuation of Mycobacterium tuberculosis.

    Directory of Open Access Journals (Sweden)

    Shyamasree De Majumdar

    Full Text Available BACKGROUND: The DevR response regulator is implicated in both hypoxic adaptation and virulence of Mycobacterium tuberculosis (M. tb. DevR regulon genes are powerfully induced in vivo implicating them in bacterial adaptation to host control strategies. A better understanding of DevR function will illumine the way for new strategies to control and treat tuberculosis. METHODOLOGY/PRINCIPAL FINDINGS: Towards this objective, we used a combination of genetic, microbiological, biochemical, cell biological tools and a guinea pig virulence assay to compare the hypoxic adaptation and virulence properties of two novel M. tb strains, namely, a devR disruption mutant, Mut1, that expresses C-terminal truncated N-terminal domain of DevR (DevR(NTD as a fusion protein with AphI (DevR(N-Kan, and its complemented strain, Comp1, that expresses intact DevR along with DevR(N-Kan. Comp1 bacteria exhibit a defect in DevR-mediated phosphosignalling, hypoxic induction of HspX and also hypoxic survival. In addition, we find that Comp1 is attenuated in virulence in guinea pigs and shows decreased infectivity of THP-1 cells. While Mut1 bacilli are also defective in hypoxic adaptation and early growth in spleen, they exhibit an overall virulence comparable to that of wild-type bacteria. CONCLUSIONS/SIGNIFICANCE: The hypoxic defect of Comp1 is associated to a defect in DevR expression level. The demonstrated repression of DevR function by DevR(N-Kan suggests that such a knockdown approach could be useful for evaluating the activity of DevRS and other two-component signaling pathways. Further investigation is necessary to elucidate the mechanism underlying Comp1 attenuation.

  20. An approach for activity-based DEVS model specification

    DEFF Research Database (Denmark)

    Alshareef, Abdurrahman; Sarjoughian, Hessam S.; Zarrin, Bahram

    2016-01-01

    activity-based behavior modeling of parallel DEVS atomic models. We consider UML activities and actions as fundamental units of behavior modeling, especially in the presence of recent advances in the UML 2.5 specifications. We describe in detail how to approach activity modeling with a set of elemental...

  1. Your data is your dogfood: DevOps in the astronomical observatory

    OpenAIRE

    Economou, Frossie; Hoblitt, Joshua C.; Norris, Pat

    2014-01-01

    DevOps is the contemporary term for a software development culture that purposefully blurs distinction between software development and IT operations by treating "infrastructure as code." DevOps teams typically implement practices summarised by the colloquial directive to "eat your own dogfood;" meaning that software tools developed by a team should be used internally rather thrown over the fence to operations or users. We present a brief overview of how DevOps techniques bring proven softwar...

  2. DevOps不是一个传说!

    Institute of Scientific and Technical Information of China (English)

    薛帆

    2015-01-01

    CA Technologies于近日发布了CA DevOps组合的升级产品——敏捷运维(Agile Operations)解决方案,该方案为组织快速部署新应用、监控动态环境、持续优化应用质量提供所需的速度和规模,从而确保卓越的客户体验。那么,此次发布的敏捷运维解决方案都包含了哪些方面的内容?该解决方案最大的功能特性在哪里?为此,记者对CA Technologies中国区高级架构师王励杰先生进行了专访。

  3. DevOps切入数字化转型

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    有类公司相信,成功采用DevOps模式必须甩掉严格进行变更管理的做派。然而,如果没有稳定的IT基础,就不可能有业务创新和员工工作效率的提升,如果企业开启“敏捷”IT之旅时,不再重视传统IT的安全性和准确性。那么其数字化转型也会一波三折。企业的目标应该是,实现敏捷性和稳定性之间的平衡。

  4. Your data is your dogfood: DevOps in the astronomical observatory

    CERN Document Server

    Economou, Frossie; Norris, Pat

    2014-01-01

    DevOps is the contemporary term for a software development culture that purposefully blurs distinction between software development and IT operations by treating "infrastructure as code." DevOps teams typically implement practices summarised by the colloquial directive to "eat your own dogfood;" meaning that software tools developed by a team should be used internally rather thrown over the fence to operations or users. We present a brief overview of how DevOps techniques bring proven software engineering practices to IT operations. We then discuss the application of these practices to astronomical observatories.

  5. 基于DevOps的软件开发管理模式

    Institute of Scientific and Technical Information of China (English)

    邹筱菁; 柯林

    2016-01-01

    文章简述了DevOps概念、基于DevOps的软件开发流程,并以K平台为例对开发流程的每一步给出了示例.DevOps本质上是将IT开发与运维合并,借助强大的管理工具,实现开发环境、测试环境和生产环境的高相似度、可编程、自动化的全生命周期配置维护管理,从而适应现代Web环境的高变动性、高可用性、高可靠性要求.DevOps是软件开发管理未来的发展趋势.

  6. DevOps-kehittäjän osaamisprofiili IT-alalla

    OpenAIRE

    Mård, Pinja

    2015-01-01

    Kandidaatintutkielmassa käsitellään DevOpsia ja sitä, minkälaista osaaamista DevOpsina toimivalta vaaditaan. DevOps on IT-alalla uusi työtehtävä, jossa sama työntekijä hoitaa sekä kehittämiseen että operointiin liittyvät tehtävät. DevOpsin avulla kommunikaatio työntekijöiden välillä paranee ja kaikki työskentelevät paremmin samaa tavoitetta kohti. Tämän uudenalaisen järjestelyn avulla pystytään muun muassa tuottamaan järjestelmiä nopeammin ja parempilaatuisena. Osaamisella t...

  7. Modeling DevOps Deployment Choices Using Process Architecture Design Dimensions

    OpenAIRE

    Babar, Zia; Lapouchnian, Alexei; Yu, Eric

    2015-01-01

    Part 8: Making Decisions in Enterprises; International audience; DevOps is a software development approach that enables enterprises to rapidly deliver software product features through process automation, greater inter-team collaboration and increased efficiency introduced through monitoring and measuring activities. No two enterprise-adopted DevOps approaches would be similar as each enterprise has unique characteristics and requirements. At present, there is no structured method in enterpri...

  8. ClinData Express – A Metadata Driven Clinical Research Data Management System for Secondary Use of Clinical Data

    OpenAIRE

    Li, Zuofeng; Wen, Jingran; Zhang, Xiaoyan; Wu, Chunxiao; Li, Zuogao; Liu, Lei

    2012-01-01

    Aim to ease the secondary use of clinical data in clinical research, we introduce a metadata driven web-based clinical data management system named ClinData Express. ClinData Express is made up of two parts: 1) m-designer, a standalone software for metadata definition; 2) a web based data warehouse system for data management. With ClinData Express, what the researchers need to do is to define the metadata and data model in the m-designer. The web interface for data collection and specific dat...

  9. CoreDevRec:Automatic Core Member Recommendation for Contribution Evaluation

    Institute of Scientific and Technical Information of China (English)

    蒋竞; 贺佳欢; 陈学渊

    2015-01-01

    The pull-based software development helps developers make contributions flexibly and effciently. Core members evaluate code changes submitted by contributors, and decide whether to merge these code changes into repositories or not. Ideally, code changes are assigned to core members and evaluated within a short time after their submission. However, in reality, some popular projects receive many pull requests, and core members have di昋culties in choosing pull requests which are to be evaluated. Therefore, there is a growing need for automatic core member recommendation, which improves the evaluation process. In this paper, we investigate pull requests with manual assignment. Results show that 3.2%∼40.6% of pull requests are manually assigned to specific core members. To assist with the manual assignment, we propose CoreDevRec to recommend core members for contribution evaluation in GitHub. CoreDevRec uses support vector machines to analyze different kinds of features, including file paths of modified codes, relationships between contributors and core members, and activeness of core members. We evaluate CoreDevRec on 18 651 pull requests of five popular projects in GitHub. Results show that CoreDevRec achieves accuracy from 72.9% to 93.5% for top 3 recommendation. In comparison with a baseline approach, CoreDevRec improves the accuracy from 18.7% to 81.3% for top 3 recommendation. Moreover, CoreDevRec even has higher accuracy than manual assignment in the project TrinityCore. We believe that CoreDevRec can improve the assignment of pull requests.

  10. Towards DevOps: Practices and Patterns from the Portuguese Startup Scene

    OpenAIRE

    Carlos Manuel da Costa Martins Teixeira

    2016-01-01

    Formed by combining the word Development with the word Operations, DevOps has been around for sometime. Uses and appearances of the word have been seen in different contexts and with different meanings making it a topic of discussion and discord. For some DevOps is a movement aiming to conciliate Operations and Developers, others believe that its just a set of tools that help automate operations tasks and procedures and others see it as a job or tittle for professionals that combine developer...

  11. Initial Service Provider DevOps concept, capabilities and proposed tools

    OpenAIRE

    John, Wolfgang; Meirosu, Catalin; Sköldström, Pontus; Nemeth, Felician; Gulyas, Andras; Kind, Mario; Sharma, Sachin; Papafili, Ioanna; Agapiou, George; Marchetto, Guido; Sisto, Riccardo; Steinert, Rebecca; Kreuger, Per; Abrahamsson, Henrik; Manzalini, Antonio

    2015-01-01

    This report presents a first sketch of the Service Provider DevOps concept including four major management processes to support the roles of both service and VNF developers as well as the operator in a more agile manner. The sketch is based on lessons learned from a study of management and operational practices in the industry and recent related work with respect to management of SDN and cloud. Finally, the report identifies requirements for realizing SP-DevOps within an combined cloud and tr...

  12. An Approach for the Implementation of Software Quality Models Adpoting CERTICS and CMMI-DEV

    Directory of Open Access Journals (Sweden)

    GARCIA, F.W.

    2015-12-01

    Full Text Available This paper proposes a mapping between two product quality and software processes models used in the industry, the CERTICS national model and the CMMI-DEV international model. The stages of mapping are presented step by step, as well as the mapping review, which had the cooperation of one specialist in CERTICS and CMMI-DEV models. It aims to correlate the structures of the two models in order to facilitate and reduce the implementation time and costs, and to stimulate the execution of multi-model implementations in software developers companies.

  13. Teaching DevOps and Cloud Computing using a Cognitive Apprenticeship and Story-Telling Approach

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak

    2016-01-01

    DevOps is a new way of developing software that is challenging from a teaching perspective. In this paper, we outline these challenges and propose teaching methods that focus on skill acquisition and technical practices that focus on performant virtualization to overcome them. We describe central...

  14. Towards an automatic model transformation mechanism from UML state machines to DEVS models

    Directory of Open Access Journals (Sweden)

    Ariel González

    2015-08-01

    Full Text Available The development of complex event-driven systems requires studies and analysis prior to deployment with the goal of detecting unwanted behavior. UML is a language widely used by the software engineering community for modeling these systems through state machines, among other mechanisms. Currently, these models do not have appropriate execution and simulation tools to analyze the real behavior of systems. Existing tools do not provide appropriate libraries (sampling from a probability distribution, plotting, etc. both to build and to analyze models. Modeling and simulation for design and prototyping of systems are widely used techniques to predict, investigate and compare the performance of systems. In particular, the Discrete Event System Specification (DEVS formalism separates the modeling and simulation; there are several tools available on the market that run and collect information from DEVS models. This paper proposes a model transformation mechanism from UML state machines to DEVS models in the Model-Driven Development (MDD context, through the declarative QVT Relations language, in order to perform simulations using tools, such as PowerDEVS. A mechanism to validate the transformation is proposed. Moreover, examples of application to analyze the behavior of an automatic banking machine and a control system of an elevator are presented.

  15. ClinData Express--a metadata driven clinical research data management system for secondary use of clinical data.

    Science.gov (United States)

    Li, Zuofeng; Wen, Jingran; Zhang, Xiaoyan; Wu, Chunxiao; Li, Zuogao; Liu, Lei

    2012-01-01

    Aim to ease the secondary use of clinical data in clinical research, we introduce a metadata driven web-based clinical data management system named ClinData Express. ClinData Express is made up of two parts: 1) m-designer, a standalone software for metadata definition; 2) a web based data warehouse system for data management. With ClinData Express, what the researchers need to do is to define the metadata and data model in the m-designer. The web interface for data collection and specific database for data storage will be automatically generated. The standards used in the system and the data export modular make sure of the data reuse. The system has been tested on seven disease-data collection in Chinese and one form from dbGap. The flexibility of system makes its great potential usage in clinical research. The system is available at http://code.google.com/p/clindataexpress.

  16. NDLS-3000配接GR-DEV-Rmg-Rmn-CAL组合仪%NDLS 3000 Combination Instrument matched with GR-DEV-Rmg-Rmn-CAL

    Institute of Scientific and Technical Information of China (English)

    陈金宏; 刘素洁; 刘国权; 徐涛

    2003-01-01

    首先简单介绍NDLS-3000的特点和华北油田砂泥岩剖面测井项目,分析其他组合测井所存在的问题.再详细说明在NDLS-3000网络双测井系统上配接GR_DEV_Rmg_Rmn_CAL组合仪的方法,包括井下仪器的连接方法和组合测井软件的编制与使用方法.

  17. Teaching DevOps and Cloud Computing using a Cognitive Apprenticeship and Story-Telling Approach

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak

    2016-01-01

    DevOps is a new way of developing software that is challenging from a teaching perspective. In this paper, we outline these challenges and propose teaching methods that focus on skill acquisition and technical practices that focus on performant virtualization to overcome them. We describe central...... elements from our course Cloud Computing and Architecture that has been designed and executed upon these methods and practices and report our experiences and lessons learned....

  18. Combinatorial regulation of the dev operon by MrpC2 and FruA during Myxococcus xanthus development.

    Science.gov (United States)

    Campbell, Ashleigh; Viswanathan, Poorna; Barrett, Terry; Son, Bongjun; Saha, Shreya; Kroos, Lee

    2015-01-01

    Proper expression of the dev operon is important for normal development of Myxococcus xanthus. When starved, these bacteria coordinate their gliding movements to build mounds that become fruiting bodies as some cells differentiate into spores. Mutations in the devTRS genes impair sporulation. Expression of the operon occurs within nascent fruiting bodies and depends in part on C signaling. Here, we report that expression of the dev operon, like that of several other C-signal-dependent genes, is subject to combinatorial control by the transcription factors MrpC2 and FruA. A DNA fragment upstream of the dev promoter was bound by a protein in an extract containing MrpC2, protecting the region spanning positions -77 to -54. Mutations in this region impaired binding of purified MrpC2 and abolished developmental expression of reporter fusions. The association of MrpC2 and/or its longer form, MrpC, with the dev promoter region depended on FruA in vivo, based on chromatin immunoprecipitation analysis, and purified FruA appeared to bind cooperatively with MrpC2 to DNA just upstream of the dev promoter in vitro. We conclude that cooperative binding of the two proteins to this promoter-proximal site is crucial for dev expression. 5' deletion analysis implied a second upstream positive regulatory site, which corresponded to a site of weak cooperative binding of MrpC2 and FruA and boosted dev expression 24 h into development. This site is unique among the C-signal-dependent genes studied so far. Deletion of this site in the M. xanthus chromosome did not impair sporulation under laboratory conditions.

  19. NCBI的ClinVar数据库及其在基因检测医学中的应用

    Institute of Scientific and Technical Information of China (English)

    白晋伟

    2014-01-01

    为加速人们理解基因序列变异与疾病表型之间的关系,美国国家生物技术信息中心(NCBI)与2012年底宣布启动ClinVar公共、免费数据库,本文旨在向国内研究者介绍ClinVar数据库产生的背景、内容和在基因检测医学研究中的应用,以促进国内研究工作者充分利用此数据库资源、开展转化医学信息学研究。

  20. Associações entre CMMI-DEV 1.2 E ISO/TS 16949

    OpenAIRE

    Altamar Urbanetz de Araújo Albanez; Carla Cristina Amodio Estorilio

    2014-01-01

    The automotive sector is one of the most daring in terms of quality, requiring ISO/TS 16949 certification. Nevertheless, there are companies those lose their certification or develop only some improvements due to a lack of enough maturity to maintain it and gaps in continuous improvement guidelines. Whereas CMMI is one of the diagnostic methods of maturity, the aim of this work is to identify the feasibility of linking the ISO/TS 16949 with the CMMI-DEV 1.2. The method used consists in review...

  1. Aplicación de herramientas DevOps en entornos de Desarrollo Web

    OpenAIRE

    MUÑOZ MARÍN, SIMÓN

    2015-01-01

    A lo largo del proyecto presentaremos la problemática a las que se enfrentan gran parte de las empresas de desarrollo web, con la gestión de los distintos entornos dónde se codifican y ejecutan sus aplicaciones. Para solucionarlo, introduciremos el movimiento DevOps y cómo herramientas creadas en torno al mismo como VirtualBox, Vagrant y Ansible, nos permiten redefinir la forma de trabajar de estas empresas y aumentar su productividad en el camino. Muñoz Marín, S. (2015). Aplic...

  2. Implementation and Analysis of DEVS Activity-Tracking with DEVSimPy

    Directory of Open Access Journals (Sweden)

    Santucci J.F.

    2013-01-01

    Full Text Available This paper deals with the implementation of Activity-Tracking (AT paradigm in the DEVSimPy environment. DEVSimPy has been developed at the SPE UMR CNRS6134 (University of Corsica in order to facilitate the modeling and the simulation of discrete-event systems described with the DEVS formalism. The AT paradigm is increasingly being used by DEVS modelers for example to improve structural aspects of models (modeling level or to make simulation more efficient using distributed or parallel algorithm (simulation level. Although DEVSimPy can be used as a software providing some features reusable for the implementation of AT paradigm (simulation profiling or step-by-step simulation, the object oriented way used to develop DEVSimPy makes it a powerful tool to implement AT paradigm in a generic manner. DEVSimPy may be viewed as an experimental framework allowing the implementation of new AT techniques while opening up new perspectives in the field of activity modeling and simulation theory.

  3. Uso de DevC++® con Delmia Quest® para Optimizar Simulaciones

    Directory of Open Access Journals (Sweden)

    Ricardo Pérez Rodríguez

    2014-01-01

    Full Text Available En este artículo se presentan los elementos básicos e imprescindibles utilizados para lograr comunicación entre cualquier algoritmo de optimización que se programe en el entorno de programación DevC++ ® y que sea utilizado para optimizar modelos de simulación en Delmia Quest ® versión R19 o superiores. El objetivo de este artículo es facilitar el aprendizaje para comunicar ambas plataformas con el fin de sistematizar y automatizar la evaluación de las soluciones desde un punto de vista práctico. El aporte central de este artículo es el desarrollo y validación de un tutorial para demostrar el proceso de intercomunicación entre Delmia Quest ® y DevC++ ® . La idea global se refiere a construir un procedimiento que enlaza las instrucciones del algoritmo de optimización programado en DevC++ ® la cuales son ejecutadas por el lenguaje de simulación Delmia Quest ® , el cual devuelve algún parámetro con la información pertinente de nuevo al algoritmo de optimización. El procedimiento se repite iterativamente de acuerdo a las especificaciones del algoritmo de optimización. Con el presente tutorial, los usuarios podrán iniciar rápidamente la programación de sus propias rutinas de comunicación inclusive en otros lenguajes de programación como Java ® ahorrado recursos en costosos cursos de capacitación. Finalmente, 10 estudiantes de ingeniería probaron la efectividad del documento, al menos 50% de ellos consumieron entre 12 y 17 minutos para terminar exitosamente la programación del tutorial propuesto, donde tradicionalmente como factor barrera se pueden requerir horas e inclusive días ya que no existe bibliografía accesible y clara en el idioma español.

  4. DevOps:协作是成功的保障

    Institute of Scientific and Technical Information of China (English)

    Richard Gerdis

    2016-01-01

    为了维持平衡,使IT部门恢复正常的运行状态,跨职能部门必须采用Dev Ops的方法,将分歧放到一边。这意味着运维团队需要从幕后走到台前,帮助提高应用的质量,尤其是那些正在开发、测试和部署的应用。如今的IT部门存在一个矛盾:敏捷开发者希望可以快速部署常规软件,而运维团队则优先考虑稳定性。开发和运维不同的成功指标使得每个团队都有自己独立的目标。

  5. Association between CMMI-DEV 1.2 AND ISO/TS 16949

    Directory of Open Access Journals (Sweden)

    Altamar Urbanetz de Araújo Albanez

    2014-05-01

    Full Text Available The automotive sector is one of the most daring in terms of quality, requiring ISO/TS 16949 certification. Nevertheless, there are companies those lose their certification or develop only some improvements due to a lack of enough maturity to maintain it and gaps in continuous improvement guidelines. Whereas CMMI is one of the diagnostic methods of maturity, the aim of this work is to identify the feasibility of linking the ISO/TS 16949 with the CMMI-DEV 1.2. The method used consists in review PDPs, quality certification and process maturity and then associate these two models. The analysis concludes that a company certified by ISO/TS not necessarily even reaches the maturity level 2 in CMMI. Moreover, while the CMMI model shows those items not covered and demand their development, ISO/TS only encourages "continuous improvement" without a plan or diagnostics for the company operationally achieve it.

  6. Experimental determination of field factors (\\Omega _{{{Q}_{\\text{clin}}},{{Q}_{\\text{msr}}}}^{{{f}_{\\text{clin}}},{{f}_{\\text{msr}}}} ) for small radiotherapy beams using the daisy chain correction method

    Science.gov (United States)

    Lárraga-Gutiérrez, José Manuel

    2015-08-01

    Recently, Alfonso et al proposed a new formalism for the dosimetry of small and non-standard fields. The proposed new formalism is strongly based on the calculation of detector-specific beam correction factors by Monte Carlo simulation methods, which accounts for the difference in the response of the detector between the small and the machine specific reference field. The correct calculation of the detector-specific beam correction factors demands an accurate knowledge of the linear accelerator, detector geometry and composition materials. The present work shows that the field factors in water may be determined experimentally using the daisy chain correction method down to a field size of 1 cm  ×  1 cm for a specific set of detectors. The detectors studied were: three mini-ionization chambers (PTW-31014, PTW-31006, IBA-CC01), three silicon-based diodes (PTW-60018, IBA-SFD and IBA-PFD) and one synthetic diamond detector (PTW-60019). Monte Carlo simulations and experimental measurements were performed for a 6 MV photon beam at 10 cm depth in water with a source-to-axis distance of 100 cm. The results show that the differences between the experimental and Monte Carlo calculated field factors are less than 0.5%—with the exception of the IBA-PFD—for field sizes between 1.5 cm  ×  1.5 cm and 5 cm  ×  5 cm. For the 1 cm  ×  1 cm field size, the differences are within 2%. By using the daisy chain correction method, it is possible to determine measured field factors in water. The results suggest that the daisy chain correction method is not suitable for measurements performed with the IBA-PFD detector. The latter is due to the presence of tungsten powder in the detector encapsulation material. The use of Monte Carlo calculated k{{Q\\text{clin}},{{Q}\\text{msr}}}{{f\\text{clin}},{{f}\\text{msr}}} is encouraged for field sizes less than or equal to 1 cm  ×  1 cm for the dosimeters used in this work.

  7. A Poética Sociológica de Medviédev e Sua Atualidade

    OpenAIRE

    Matheus de Brito

    2013-01-01

    Review of Pável Nikoláievitch Medviédev. O método formal nos estudos literários: introdução crítica a uma poética sociológica, Trad. Ekaterina Vólkova Américo e Sheila Camargo Grillo, São Paulo, Contexto, 2012, 269 pp. [1ª ed., Leningrado, Pribói, 1928]. ISBN 978-85-7244-725-6

  8. clin et restauration de la population de truites lacustres (Salmo trutta lacustris L. du lac de Constance

    Directory of Open Access Journals (Sweden)

    RUHLÉ C.

    1990-10-01

    Full Text Available Le déclin de la population de truites migratrices du lac de Constance a débuté vers 1950 quand un barrage a été construit sur le Rhin, affluent principal de ce lac, coupant ainsi l'accès aux plus importantes frayères. Ceci a suffi de prétexte pour renoncer à une longueur de capture garantissant la reproduction naturelle. Par la suite, la population en train de diminuer a servi de justification pour des déversements importants de truites arc-en-ciel. Un désintérêt croissant pour le maintien de frayères dans les affluents secondaires a, finalement, contribué à la baisse des captures de 12.000 kg à 3.000 kg entre 1950 et 1980.Les mesures réalisées au cours des dernières années pour restaurer la population de truites lacustres ont du succès. Il s'agit surtout de : — la détermination d'une nouvelle longueur de capture ainsi que de périodes de protection respectant la reproduction des truites migrant à longue et à courte distance,— l'élevage de stocks de géniteurs, — les déversements forcés et effectués surtout en affluents (au lieu du lac,— l'interdiction d'immersions de truites arc-en-ciel,— l'abolition de barrages. Le succès se manifeste par un nombre croissant de truites observées frayant dans les affluents ainsi que par des captures de plus en plus nombreuses faites par la pêche professionnelle.

  9. Sustainability Comparison between EnDev and not-EnDev Micro-Hydro Power (MHP) in Indonesia : Analysis of the long-term technical, social, environmental and economic sustainability of the rural energy infrastructure of MHP in Indonesia

    OpenAIRE

    Ranzanici, Andrea

    2013-01-01

    The Energising Development (EnDev) initiative, for which the GIZ acts as implementing agency, promotes the supply of modern energy technologies to households and small‐scale businesses in the rural communities of 24 countries in Africa, Latin America and Asia. In Indonesia, this has been achieved through off‐grid micro‐hydro (MHP) and solar power mini‐grids and since 2006 230 MHP and 117 solar projects have been supported to varying degree at substantial cost, reaching more than 167 thousand ...

  10. A Poética Sociológica de Medviédev e Sua Atualidade

    Directory of Open Access Journals (Sweden)

    Matheus de Brito

    2013-07-01

    Full Text Available Review of Pável Nikoláievitch Medviédev. O método formal nos estudos literários: introdução crítica a uma poética sociológica, Trad. Ekaterina Vólkova Américo e Sheila Camargo Grillo, São Paulo, Contexto, 2012, 269 pp. [1ª ed., Leningrado, Pribói, 1928]. ISBN 978-85-7244-725-6

  11. IBM将通过DevOps战略助企业实现移动和云计算创新

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    IBM2013技术峰会日前在京举行,众多创新技术和理念在会上发布,其中以Dev019s软件持续交付为核心的移动、云计算的开发创新成为亮点。据了解,IBM本次推出的一系列新软件、培Sling资源,将有助于推动全球及中国企业机构、开发人员及IT专业人士在移动和云计算应用领域的创新,帮助他们更好地创建、测试和交付基于移动和云计算的应用程序。

  12. Activity-based simulation using DEVS:increasing performance by an activity model in parallel DEVS simulation

    Institute of Scientific and Technical Information of China (English)

    Bin CHEN; Lao-bing ZHANG; Xiao-cheng LIU; Hans VANGHELUWE

    2014-01-01

    Improving simulation performance using activity tracking has attracted attention in the modeling field in recent years. The reference to activity has been successfully used to predict and promote the simulation performance. Tracking activity, how-ever, uses only the inherent performance information contained in the models. To extend activity prediction in modeling, we propose the activity enhanced modeling with an activity meta-model at the meta-level. The meta-model provides a set of interfaces to model activity in a specific domain. The activity model transformation in subsequence is devised to deal with the simulation difference due to the heterogeneous activity model. Finally, the resource-aware simulation framework is implemented to integrate the activity models in activity-based simulation. The case study shows the improvement brought on by activity-based simulation using discrete event system specification (DEVS).

  13. Darba devēju un darbinieku atbildības tiesiskais regulējums darba aizsardzībā

    OpenAIRE

    Lapuška, Baiba

    2012-01-01

    Bakalaura darba „Darba devēju un darbinieku atbildības tiesiskais regulējums darba aizsardzībā” mērķis ir izpētīt normatīvo regulējumu, kas attiecas uz darba devēja un darbinieka tiesībām un pienākumiem darba aizsardzības jomā, kā arī vērst uzmanību uz problēmjautājumiem, kas skar darba devēja atbildību par darba aizsardzības neievērošanu. Autore uzskata, ka tiesu praksē nav pievērsta pietiekama uzmanība darba devēja un darbinieka atbildības tiesiskajam regulējumam darba aizsardzībā. Šis tema...

  14. Devínska Kobyla – a window into the Middle Miocene shallow-water marine environments of the Central Paratethys (Vienna Basin, Slovakia

    Directory of Open Access Journals (Sweden)

    Matúš Hyžný

    2012-10-01

    Full Text Available Middle Miocene strata exposed at Devínska Kobyla Hill (Malé Karpaty Mts document the temporal and spatial changes in shallow-water environments of the northern Vienna Basin during the Late Badenian and Early Sarmatian. Middle Miocene deposits of the Studienka and Holíč formations border this hill essentially along its full perimeter. The present overview of 16 localities based on published observations and new sampling shows that the Middle Miocene deposits contain species-rich micro- and macrofaunal assemblages as well as nannoflora. This contribution includes lists of all marine faunal (except tetrapods and microfloral taxa known to date. The localities can be divided into three groups on the basis of their lithology and the abundance of molluscs and foraminifers in fossil assemblages: Devín area, Dúbravka area and Devínska Nová Ves area. On the basis of foraminifers the localities in the Dúbravka area (Dúbravská hlavica, Pektenová lavica, Starý lom, partly Fuchsov lom can be assigned to the Early Sarmatian (based on benthic taxa, whereas the localities in the Devín (Šibeničný vrch, Štítová, Terasy, Lomnická, Lingulová lavica, Glosusová lavica and Devínska Nová Ves (Sandberg 1–2, Malý Sandberg, Waitov lom, Glavica, Štokeravská vápenka-Bonanza areas are predominantly of the Late Badenian age (based on benthic and planktonic taxa. However, molluscs imply that the deposits from the Dúbravka area are of Late Badenian age. The differences in the estimates of stratigraphic age between on molluscs and foraminifers can be explained with the persistence of typically Badenian mollusc taxa in the marginal parts of the Central Paratethys Sea during the Middle Miocene. For every studied locality palaeoenvironmental conditions based mostly on molluscs and foraminifers are inferred.

  15. 基于DEVS的作战指挥行为建模研究%Study on Combat Commanding Behavior Modeling Based on DEVS

    Institute of Scientific and Technical Information of China (English)

    李京; 王子明; 李冬

    2014-01-01

    针对传统计算机兵力生成(computer generated force,CGF)建模所使用的经典人工智能编程语言存在的不足,提出一种基于离散事件系统(discrete event system specification,DEVS)的作战指挥行为建模方法。从DEVS原子模型和耦合的DEVS模型对DEVS做规范介绍,统一、规范描述指挥主体的生理和心理因素如何影响作战指挥行为,建立一种包含评估模块、压力模块和行为模块的作战指挥行为模型。结果表明:该模型能很好地将指挥主体的压力和自身生理状况融入到作战指挥行为中,能较为合理地反映出在紧张对抗环境中指挥主体的实际指挥行为。%Aiming at the shortcoming of typical artificial intelligence programming language for traditional computer generated force (CGF) modeling, put forward a new modeling method of combat commanding behavior based on discrete event system specification (DEVS). From DEVS atomic model and coupling DEVS model, make a standard introduction for DEVS, and also make an unified and standard description about how the physiological and psychological factors of commander make an influence on commanding behavior, establish a commanding behavior model which including evaluation model, pressure model and behavior model. The results show that the model can combine the commander pressure and physiological state with commanding behavior, and it can reflect reasonably the commanding behavior under the circumstance full of nervousness and confrontation.

  16. Calculation of direct antiretroviral treatment costs and potential cost savings by using generics in the German HIV ClinSurv cohort.

    Directory of Open Access Journals (Sweden)

    Matthias Stoll

    Full Text Available UNLABELLED: BACKGROUND/AIM OF THE STUDY: The study aimed to determine the cost impacts of antiretroviral drugs by analysing a long-term follow-up of direct costs for combined antiretroviral therapy, cART, -regimens in the nationwide long-term observational multi-centre German HIV ClinSurv Cohort. The second aim was to develop potential cost saving strategies by modelling different treatment scenarios. METHODS: Antiretroviral regimens (ART from 10,190 HIV-infected patients from 11 participating ClinSurv study centres have been investigated since 1996. Biannual data cART-initiation, cART-changes, surrogate markers, clinical events and the Centre of Disease Control- (CDC-stage of HIV disease are reported. Treatment duration was calculated on a daily basis via the documented dates for the beginning and end of each antiretroviral drug treatment. Prices were calculated for each individual regimen based on actual office sales prices of the branded pharmaceuticals distributed by the license holder including German taxes. RESULTS: During the 13-year follow-up period, 21,387,427 treatment days were covered. Cumulative direct costs for antiretroviral drugs of €812,877,356 were determined according to an average of €42.08 per day (€7.52 to € 217.70. Since cART is widely used in Germany, the costs for an entire regimen increased by 13.5%. Regimens are more expensive in the advanced stages of HIV disease. The potential for cost savings was calculated using non-nucleotide-reverse-transcriptase-inhibitor, NNRTI, more frequently instead of ritonavir-boosted protease inhibitor, PI/r, in first line therapy. This calculation revealed cumulative savings of 10.9% to 19.8% of daily treatment costs (50% and 90% substitution of PI/r, respectively. Substituting certain branded drugs by generic drugs showed potential cost savings of between 1.6% and 31.8%. CONCLUSIONS: Analysis of the data of this nationwide study reflects disease-specific health services research

  17. Analysing inter-relationships among water, governance, human development variables in developing countries: WatSan4Dev database coherency analysis

    Science.gov (United States)

    Dondeynaz, C.; Carmona Moreno, C.; Céspedes Lorente, J. J.

    2012-01-01

    The "Integrated Water Resources Management" principle was formally laid down at the International Conference on Water and Sustainable development in Dublin 1992. One of the main results of this conference is that improving Water and Sanitation Services (WSS), being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation). These sectors influence or are influenced by the access to WSS. The understanding of these interrelations appears as crucial for decision makers in the water sector. In this framework, the Joint Research Centre (JRC) of the European Commission (EC) has developed a new database (WatSan4Dev database) containing 45 indicators (called variables in this paper) from environmental, socio-economic, governance and financial aid flows data in developing countries. This paper describes the development of the WatSan4Dev dataset, the statistical processes needed to improve the data quality; and, finally, the analysis to verify the database coherence is presented. At the light of the first analysis, WatSan4Dev Dataset shows the coherency among the different variables that are confirmed by the direct field experience and/or the scientific literature in the domain. Preliminary analysis of the relationships indicates that the informal urbanisation development is an important factor influencing negatively the percentage of the population having access to WSS. Health, and in particular children health, benefits from the improvement of WSS. Efficient environmental governance is also an important factor for providing improved water supply services. The database would be at the base of posterior analyses to better understand the interrelationships between the different indicators associated in the water sector in developing countries. A data model using the different indicators will be realised on the next phase of this research work.

  18. Analysing inter-relationships among water, governance, human development variables in developing countries: WatSan4Dev database coherency analysis

    Directory of Open Access Journals (Sweden)

    C. Dondeynaz

    2012-01-01

    Full Text Available The "Integrated Water Resources Management" principle was formally laid down at the International Conference on Water and Sustainable development in Dublin 1992. One of the main results of this conference is that improving Water and Sanitation Services (WSS, being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation. These sectors influence or are influenced by the access to WSS. The understanding of these interrelations appears as crucial for decision makers in the water sector. In this framework, the Joint Research Centre (JRC of the European Commission (EC has developed a new database (WatSan4Dev database containing 45 indicators (called variables in this paper from environmental, socio-economic, governance and financial aid flows data in developing countries.

    This paper describes the development of the WatSan4Dev dataset, the statistical processes needed to improve the data quality; and, finally, the analysis to verify the database coherence is presented.

    At the light of the first analysis, WatSan4Dev Dataset shows the coherency among the different variables that are confirmed by the direct field experience and/or the scientific literature in the domain. Preliminary analysis of the relationships indicates that the informal urbanisation development is an important factor influencing negatively the percentage of the population having access to WSS. Health, and in particular children health, benefits from the improvement of WSS. Efficient environmental governance is also an important factor for providing improved water supply services.

    The database would be at the base of posterior analyses to better understand the interrelationships between the different indicators associated in the water sector in developing countries. A data model using the different indicators will be realised

  19. Antiutopiskie romāni pusaudžiem „Citādie”, „Delīrijs”, „Devējs”

    OpenAIRE

    Korčevska, Jūlija

    2015-01-01

    Šis pētījums ir veltīts antiutopiskās pusaudžu literatūras analīzei V. Rotas grāmatā „Citādie”, L. Oliveras romānā „Delīrijs” un L. Lorijas darbā „Devējs”. Darba teorētisko daļu veido informācija par pusaudžiem domāto literatūru utopiskās un antiutopiskās literatūras žanru attīstību. Praktiskā daļa veltīta antiutopijas pazīmju analīzei pusaudžiem paredzētajās grāmatās „Citādie”, „Delīrijs” un „Devējs”. Pētījumā izmantota kvalitatīvā pētījumu metode, kas sevī ietver saistīto teoriju izpēti un ...

  20. Identificando Hallazgos de Mejora en Pymes de TI Utilizando un Modelo Ontológico para CMMI-DEV v1.3

    Directory of Open Access Journals (Sweden)

    J. Guadalupe Uribe Dévora

    2013-12-01

    Full Text Available Uno de los principales requisitos que deben cumplir las pymes de desarrollo de software es adoptar un estándar o modelo para garantizar la calidad de sus productos. Sin embargo, este tipo de organización, carece o no tienen procesos bien definidos. En este contexto implementar un modelo o estándar de calidad para estas organizaciones enfrenta algunos obstáculos como: gran desconocimiento sobre éstos, su adopción representa una curva de aprendizaje prolongado, las certificaciones de estos modelos o estándares para las pymes y su personal representan costos muy elevados. Por lo tanto, en este artículo se presenta una herramienta ontológica basada en el Modelo CMMI-DEV v1.3. El objetivo principal es proveer a las pymes de una herramienta que contraste sus procesos actuales obtenidos a través de un método para la extracción del conocimiento tácito versus los procesos de CMMI-DEV v1.3 para detectar posibles hallazgos de mejora e implementar mejoras en sus procesos organizacionales.

  1. Relancer Saint-Étienne. Conditions institutionnelles et capacité d’action collective dans une ville en déclin

    Directory of Open Access Journals (Sweden)

    Vincent Béal

    2010-11-01

    Full Text Available L'objectif de cet article est de comprendre comment une capacité d’action collective peut se construire dans une ville marquée par une industrialisation ancienne et, plus récemment, par un déclin démographique et économique. La thèse principale de l'article, inspirée par l’économie politique et le néo-institutionnalisme, est que la difficulté d’un territoire d’ancienne industrialisation à constituer une capacité d’action collective peut certes s’expliquer par une position défavorable dans la nouvelle division internationale du travail mais aussi par les conditions institutionnelles engendrées par ce passé industriel et la crise économique et démographique. Dans le cas de Saint-Étienne analysé dans cet article, les modalités historiques de l’industrialisation mais aussi les modalités de gestion de la crise de désindustrialisation ont engendré des conditions institutionnelles –dispositions à la prise de parole età la coopération, nature des rapports entre les différents types d’organisation (milieux économiques, classe politique locale, État- peu favorables à l’émergence d’une capacité d’action collective et à l’élaboration de stratégies partagées de sortie de crise.The objective of the article is to understand how a political capacity can emerge in a city characterised by an ancient process of industrialisation and, more recently, by an economic and demographic decline. The central thesis of the article is inspired by political economy and neo-institutionalism. One considers that the difficulties faced by a place of old industry to build up a political capacity can admittedly be explained by an unfavourable position in the international division of labour but also the institutional conditions generated by the industrial past and the economic and demographic crisis. In the case of the French city of Saint-Étienne, analysed in this article, the historical modalities in which

  2. Les anneaux de tufs enfouis : une nouvelle cible pour la recherche de ressources en eau en terrain volcanique. L'exemple des captages de Vourzac (Devès, Massif central français)Hidden tuff rings: a new target for water resource prospecting in volcanic rocks. The case of the well field of Vourzac (Devès, French Massif Central)

    Science.gov (United States)

    Boivin, Pierre; Livet, Marc

    2001-06-01

    Several independent and abundant springs are located in the valley of Vourzac. The geological context is a phreatomagmatic tuff-ring overlaid by a Strombolian cone, the two being interbedded in the Devès basaltic plateau. The tuff ring acts as a radial drainpipe system, which collects water at its periphery and drives it to the central part of the ring. The springs are at the intersection of the drainpipe with the talweg of the Vourzac valley. The basaltic plateaus, frequently associated with maars, could often contain such hidden tuff rings. Their detection could be useful to locate and exploit confined aquifers.

  3. La susceptibilidad magnética del batolito de Achala (Devónico, Sierra Grande de Córdoba y sus diferencias con otros granitos achalianos

    Directory of Open Access Journals (Sweden)

    Silvana E. Geuna

    2008-09-01

    Full Text Available El magmatismo devónico de las Sierras Pampeanas de Córdoba y San Luis está representado por batolitos y plutones de composición monzogranítica y forma subelíptica, emplazados en un basamento metamórfico-plutónico eopaleozoico. Se distinguen dos grupos: el primero, compuesto por granitoides con hornblenda-biotita, metaluminosos a débilmente peraluminosos; y el segundo, formado por granitoides con biotita y muscovita, peraluminosos. Ambos grupos se caracterizan respectivamente por tener magnetita e ilmenita como fases accesorias, lo cual genera propiedades magnéticas distintivas. Entre ellos, el batolito de Achala, Córdoba, con una extensión de casi 2.500 km², es un buen exponente de los granitos paramagnéticos (no magnéticos. Su mineralogía magnética fue caracterizada en cuarenta y un sitios, la mayoría de ellos en el Monzogranito Achala. Se determinó una susceptibilidad magnética promedio muy baja, 15 x 10-5 (SI, controlada por el contenido de biotita e ilmeno- hematita. Veintiún sitios mostraron remanencia magnética estable portada por hematita, que aparece como un mineral accesorio, intercrecida con discos de exsolución de (hemoilmenita. La anisotropía de susceptibilidad magnética es débil y predominan las formas obladas, como es usual en fábricas magmáticas de granitos paramagnéticos; casi no se obtuvieron lineaciones. El grado de anisotropía es mayor en zonas con cizallamiento magmático, debido al efecto de la deformación subsolidus. El magnetismo débil del monzogranito de Achala contrasta con el carácter magnético de los plutones monzograníticos porfíricos más representativos de otros batolitos de la región, como Renca, Cerro Áspero y Las Chacras-Piedras Coloradas. La virtual ausencia de magnetita, junto con la presencia de ilmeno-hematita exsuelta, indica que un enfriamiento bajo condiciones oxidantes sería el responsable del carácter paramagnético de Achala. Como consecuencia de aplicación pr

  4. Evidencia Empírica de la Minería de Procesos en la Implantación de CMMI-DEV

    Directory of Open Access Journals (Sweden)

    Paola E. Velazquez-Solis

    2016-11-01

    Full Text Available La minería de procesos tiene como objetivo descubrir, monitorear y mejorar procesos a través del análisis de los diversos registros de eventos generados por los procesos de la organización. El objetivo de este trabajo es presentar la evidencia empírica de la inclusión estratégica de la disciplina de minería de procesos en proyectos de mejora de procesos de software implementados con CMMI. En el proceso de mapeo sistemático de la revisión de la literatura, se establecieron cuatro categorías para clasificar los hallazgos encontrados (Fundamentos teóricos, propuestas, herramientas y sistemas de información y algoritmos para presentar los estudios que cumplen con el objetivo. Se concluye que la interdisciplinariedad de la minería de procesos con un modelo de referencia de procesos como CMMI-DEV apoya la implementación y evaluación de las áreas de procesos, al aplicar técnicas y algoritmos de minería de procesos que faciliten la exploración y explotación de los registros de eventos relacionados a la ejecución de las actividades almacenados en un repositorio.

  5. Identification of Candida haemulonii Complex Species: Use of ClinProTools(TM) to Overcome Limitations of the Bruker Biotyper(TM), VITEK MS(TM) IVD, and VITEK MS(TM) RUO Databases.

    Science.gov (United States)

    Grenfell, Rafaella C; da Silva Junior, Afonso R; Del Negro, Gilda M B; Munhoz, Regina B; Gimenes, Viviane M F; Assis, Diego M; Rockstroh, Anna C; Motta, Adriana L; Rossi, Flavia; Juliano, Luiz; Benard, Gil; de Almeida Júnior, João N

    2016-01-01

    Candida haemulonii is now considered a complex of two species and one variety: C. haemulonii sensu stricto, Candida duobushaemulonii and the variety C. haemulonii var. vulnera. Identification (ID) of these species is relevant for epidemiological purposes and for therapeutic management, but the different phenotypic commercial systems are unable to provide correct species ID for these emergent pathogens. Hence, we evaluated the MALDI-TOF MS performance for the ID of C. haemulonii species, analyzing isolates/strains of C. haemulonii complex species, Candida pseudohaemulonii and Candida auris by two commercial platforms, their databases and softwares. To differentiate C. haemulonii sensu sctricto from the variety vulnera, we used the ClinProTools(TM) models and a single-peak analysis with the software FlexAnalysis(TM). The Biotyper(TM) database gave 100% correct species ID for C. haemulonii sensu stricto, C. pseudohaemulonii and C. auris, with 69% of correct species ID for C. duobushaemulonii. Vitek MS(TM) IVD database gave 100% correct species ID for C. haemulonii sensu stricto, misidentifying all C. duobushaemulonii and C. pseudohaemulonii as C. haemulonii, being unable to identify C. auris. The Vitek MS(TM) RUO database needed to be upgraded with in-house SuperSpectra to discriminate C. haemulonii sensu stricto, C. duobushaemulonii, C. pseudohaemulonii, and C. auris strains/isolates. The generic algorithm model from ClinProTools(TM) software showed recognition capability of 100% and cross validation of 98.02% for the discrimination of C. haemulonii sensu stricto from the variety vulnera. Single-peak analysis showed that the peaks 5670, 6878, or 13750 m/z can distinguish C. haemulonii sensu stricto from the variety vulnera.

  6. Green House Angel&Dev

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    这个叫做Angel&Devil的可爱小东西,是GreenHouse公司推出的新款时尚型入耳式耳机。这款耳机右耳是天使的造型,左耳则设计成魔鬼的样子,共有5款颜色可以选择。这耳机的接口处均进行了镀金处理,频率响应为20Hz-20000Hz,阻抗为16欧姆,输入功率最大5mW。

  7. Devónico de la Sierra de la invernada, precordillera de San Juan, Argentina: revisión estratigráfica e implicancias paleogeográficas

    Directory of Open Access Journals (Sweden)

    Silvio H Peralta

    2013-06-01

    Full Text Available En este trabajo se describe e interpreta desde punto de vista estratigráfico la sucesión marino-clástica del Devónico expuesta en el flanco oriental de la Sierra de la Invernada, desde el área de Gualilán, al norte, hasta el área de Pachaco, al sur, Precordillera Central de San Juan. La aludida sucesión está integrada por las formaciones Punta Negra (Emsiano-Eifeliano? y Los Sombreros (ex "Formación Corralito" (Devónico post-Formación Punta Negra, destacándose en el área la ausencia de la Formación Talacasto (Lochkoviano - Emsiano cuyos depósitos se encuentran resedimentados en los olistostromas de la Formación Los Sombreros. La Formación Punta Negra presenta arreglo general estrato-granocreciente; en el área de Gualilán, sobreyace en paraconcordancia a la Formación Los Espejos, mientras que en el área de Pachaco sobreyace a la Formación Los Bretes (Hirnantiano a Wenlokiano, evidenciando un hiatus que incluye a las formaciones Los Espejos y Talacasto. En toda el área de estudio, la Formación Punta Negra se observa cubierta en paraconcordancia (superficie erosiva por depósitos de olistostroma de la Formación Los Sombreros, los cuales, sobre la base de sus relaciones estratigráficas, características litológicas y paleobiológicas, se sugiere serían el resultado de un evento distensivo acaecido en el Devónico post-Formación Punta Negra. La falta de registro de la Formación Talacasto se interpreta como resultado del basculamiento de la cuenca Devónica hacia el norte, debido al control del Alto del Tambolar.

  8. Latvijas sabiedrisko attiecību speciālistu profesionalitāte: darba devēju sniegtais novērtējums un pašvērtējums (2014)

    OpenAIRE

    Lūse, Everita

    2014-01-01

    Maģistra darba tēma ir „Latvijas sabiedrisko attiecību speciālistu profesionalitāte: darba devēju sniegtais novērtējums un pašvērtējums (2014)”. Darbā izvirzītā problēma ir, vai un kā sabiedrisko attiecību speciālistam piemītošās zināšanas un prasmes ietekmē šī speciālista profesionalitātes pašvērtējumu un darba devēju sniegto novērtējumu. Maģistra darba teorētiskajā daļā aplūkota Dž. Gruniga izstrādātā lieliskuma teorija sabiedriskajās attiecībās, sabiedrisko attiecību speciālistu l...

  9. The evolution of the Late Badenian calcareous nannofossils assemblages as an reflexion of the palaeoenvironmental changes of the Vienna Basin (Devínska Nová Ves – clay pit, Slovakia

    Directory of Open Access Journals (Sweden)

    Michal Jamrich

    2010-01-01

    Full Text Available This paper discusses the results of high resolution study of the Late Badenian calcareous nannofossils from the Studienka Formation of the Vienna Basin, locality Devínska Nová Ves – clay pit (section DNV 1. Results are based on quantitative data of nannofossil assemblages from the sixty nine samples of the studied profile. The age of sediments was determined as Late Badenian and correlated with NN6 – Discoaster exilis Zone. Abundance of the species Holodiscolithus macroporus was noticed, quantified and interpreted for the first time. Abundance patterns indicate: (1 nearshore environment with nutrient supply (prevailing of small Reticulofenestra over Coccolithus pelagicus; (2 cooling trend (by abundance of Holodiscolithus macroporus, Coccolithus pelagicus; low abundance of sphenoliths and rare discoasterids; (3 eutrophy (local enrichment of species Helicosphaera and Syracosphaera pulchra; (4 salinity decrease (higher number of Braarudosphaera bigelowii bigelowii, B. bigelowii parvula, Micrantholithus flos and M. vesper; (5 higher turbulence of palaeoenvironment (locally higher abundance of helicospherids; (6 signal of higher erosion rate (local increase of reworked nannofossils. Cluster analysis according to ecological demands was performed on the assemblage data. Four groups related to different temperature and trophic conditions have been distinguished.

  10. Point of Care Tools im Vergleich des Universitätsklinikums Hamburg-Eppendorf (UKE: UpToDate, ClinicalResource@Ovid/Clin-eguide und Dynamed / Point of Care Tools in comparison at the University Medical Center Hamburg-Eppendorf: UpToDate, ClinicalResource@Ovid and Dynamed

    Directory of Open Access Journals (Sweden)

    Menn, Elke

    2006-09-01

    Full Text Available Point of Care Tools are used for clinical decision making – UpToDate is also used in continuing medical education. These databases compile only evidence-based knowledge which is updated regularly. Using Point of Care Tools promises to improve clinical outcomes. UpToDate has been used at the University Hospital Hamburg-Eppendorf for the last four years. In a recent trial the use of ClinicalResource@Ovid/Clin-eguide and Dynamed has been evaluated in comparison with UpToDate.

  11. Fıtrat Hadisi’nin Osmanlı'nın Devşirme Sisteminde Hayata Aksedişi 'The Hadith of Fitrah’ And How It Is Reflected On Life Ottoman’s Devshirme System

    Directory of Open Access Journals (Sweden)

    Mustafa IŞIK

    2013-07-01

    -culture on thisevent with together ‘Devshirme’. ‘Her çocuk, fıtrat üzere doğar; sonra onu ana-babası Yahudileştirir, Hıristiyanlaştırır veya Mecusîleştirir’ hadisi, temel İslam bilimlerinde ‘fıtrat hadisi’ olarak bilinir. İslami literatürde, geçmişten günümüze, bu hadis hakkında çeşitli görüşler ortaya konmuştur. Fıtrat hadisinin, klasik hadis literatüründeki kaynakları ve hadis imamlarının bu hadise bakışları açısından daha çok ‘Çocuğun ölmesi halinde dinî ve hukukî durumunun ne olacağı?’ sorusu üzerinde durulmuştur. Ancak hadis bilginleri ve bazı interdisipliner İslam âlimleri, fıtrat’ın ‘insanlığın ortak dinî temeli’ olduğuna inanmaktadırlar. Bu görüşe bağlı olarak biz, fıtrat hadisi’nin Osmanlı’daki ‘devşirme’ hadisesiyle örtüştüğünü düşünüyoruz. Devşirme sisteminin, tarihi bir olgu olarak, Osmanlı’da gerçekleşen halini ele almak istiyoruz. Bu haliyle Osmanlı Devleti bu olguyu sistemleştirip kanun, tüzük ve yönetmeliği olan bir sistem haline koymadan önce dini yönünü hesaba kattığını; bu hadisteki ‘fıtrat gerçeği’nden hareket etmiş olabileceğini; güçlü kaslar ve çalışkan beyinler sayesinde özelde devletine genelde insanlığa hizmet ettiğini var sayıyoruz. O günün dünya devleti olan Osmanlı’dan bugünün dünya devleti ABD’ye baktığımızda, işleyiş ve yöntem farklı olsa da, birtakım paralellikler görmekteyiz. Farklı asırlarda, değişik coğrafyalarda, birbirine benzemeyen iki büyük medeniyetin ortaya koyduğu uygulamadaki benzerlik ve ulaştığı ortak nokta, eğitimin, başat belirleyici olduğu gerçeğidir. Bu makalenin amacı, sadece tarihî bir fenomeni dile getirmek değil; fıtratın anlamını, geçerliliğini bu tarihî olgudan hareketle yinelemektir. Makalemizde bu konuyu fıtrat yani insanın değişmeyen varlık yapısı ve eğitim-kültürün bu yapıya etkisini ‘devşirme’ olgusuyla

  12. Forcecom Developer Certification Handbook (DEV401)

    CERN Document Server

    Kabe, Siddhesh

    2012-01-01

    A practical guide that will help you discover fundamentals for building applications on Force.com without writing a single line of code. If you are new to the Force.com platform and want to learn from scratch, it is advisable that you begin with the first chapter and move on to the last. However, if you are familiar with Force.com and want to understand in detail some aspect of it, you can dip into any chapter. Each certification module is covered in a separate chapter, and is accompanied by questions being asked in the exams. Developers who need to prepare for the Salesforce.com Certified For

  13. Architectural Implications of DevOps

    Science.gov (United States)

    2014-03-27

    Project Management Approach Size Metrics Years In Use Release Cadence CI Cadence A Agile/ Scrum (last 2 years and traditional before...that) 1M SLOC 17 Client release available every 2 months (not all accept it) Daily CI build B Water/ Scrum /F all 3M SLOC, team size 6– 8...90,000 users 3+ Internal release every 2–3 weeks, external release as needed Daily CI build C Agile/ Scrum Team size 30 2+ Internal release every

  14. ComDev in the Mediatized World

    DEFF Research Database (Denmark)

    Tufte, Thomas; Hemer, Oscar

    2012-01-01

    In late 2011 we are in the beginning of a revolution that may or may not turn out to be more far-reaching than the one unleashed in 1989. A common denominator in this resurging revolution is the mobilizing power of the so-called social media. Even if labels such as the Twitter or Facebook...... revolution are rightfully refuted, the on-going Arab Spring is a clear-cut example of an unprecedented communication power, largely out of the authorities’ control. While the crucial role of media and communication in processes of social change at last becomes evident, it is however not associated...

  15. Prokaryotic Expression of DEV Extracellular gD Gene and Its Subcellular Localization in Virus-infected DEF%鸭肠炎病毒gD基因胞外区的原核表达及在感染鸭胚成纤维细胞中的定位

    Institute of Scientific and Technical Information of China (English)

    刘琰; 徐凝; 付培芬; 母晓宇; 董井泉; 马波; 王君伟

    2012-01-01

    The extracellular gD gene was amplified by PCR from DEV genomic DNA according to our laboratory discovered gene sequence (GenBank accession number EU714267). The recombi-nant expression plasmid pET-30a-gDw could effectively express gDw fusion protein that was used to immunize rabbits. The titer of antibody tested by agar diffusion reaction was 1:16. Plaque reduction neutralization test showed that its neutralization antibody titer was up to 1:64. By indi-rected immunofluorescencei the results showed that gD appeared in the cell cytoplasm near the nuclear as early as 4 hours post infection. After 12 hours post infection, the fluorescence in cytoplasm was increased. Above all, the results afforded significant data for the study on the function of DEV gD.%以本实验室获得的鸭肠炎病毒(DEV) C-KCE株US区基因序列(GenBank登录号EU714267)为基础PCR扩增出gD基因胞外区(gDw),将其定向克隆至原核表达载体pET-30a(+)并转化至大肠杆菌RosettaTM(DE3)pLys.经IPTG诱导表达,SDS-PAGE分析表明gD基因胞外区在大肠杆菌中获得与预期大小相符的表达蛋白.重组蛋白纯化后免疫家兔制备多克隆抗体,血清琼扩效价达1∶16,噬斑减数中和试验测定血清中和抗体效价达1∶64.通过免疫荧光技术首次对gD进行亚细胞定位检测,结果表明DEV感染鸭胚成纤维细胞(DEF)后4h近核区域细胞质内首先开始出现荧光,12h以后显著增加,明显的点状绿色荧光广泛存在于胞质中.本研究为进一步开展DEV gD的功能研究提供了重要数据和材料.

  16. Disease: H00256 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ndromes. Endocr Dev 13:99-116 (2008) PMID:17161331 Metherell LA, Chan LF, Clark AJ The genetics of ACTH resistance syndromes. Best Pract Res Clin Endocrinol Metab 20:547-60 (2006) ...

  17. Disease: H00093 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available , Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) ...312863 613179 603554 233650 612782 612783 PMID:17162365 (gene) Kumar A, Teuber SS

  18. Point-of-Care Healthcare Databases Are an Overall Asset to Clinicians, but Different Databases May Vary in Usefulness Based on Personal Preferences. A Review of: Chan, R. & Stieda, V. (2011. Evaluation of three point-of-care healthcare databases: BMJ Point-of-Care, Clin-eguide and Nursing Reference Centre. Health and Information Libraries Journal, 28(1, 50-58. doi: 10.1111/j.1471-1842.2010.00920.x

    Directory of Open Access Journals (Sweden)

    Carol D. Howe

    2011-01-01

    Full Text Available Objective – To evaluate the usefulness of three point-of-care healthcare databases (BMJ Point-of-Care, Clin-eguide, and Nursing Reference Centre in clinical practice.Design – A descriptive study analyzing questionnaire results.Setting – Hospitals within Alberta, Canada’s two largest health regions (at the time of this study, with a third health region submitting a small number of responses.Subjects – A total of 46 Alberta hospital personnel answered the questionnaire, including 19 clinicians, 7 administrators, 6 nurses, 1 librarian, 1 preceptor, and “some” project coordinators. Subjects were chosen using a non-probability sampling method.Methods – The researchers developed an online questionnaire consisting of 17 questions and posted it on the University of Calgary’s Health Sciences Library and the Health Knowledge Network websites. The questions, in general, asked respondents how easy the databases were to search and use, whether the database content answered their clinical questions, and whether they would recommend the databases for future purchase. Most questions required a response for each of the three databases. The researchers collected quantitative data by using a Likert scale from 1 to 5, with 5 being the most positive answer and 1 being the most negative. They collected qualitative data by asking open-ended questions.Main Results – With regard to ease of searching, BMJ Point-of-Care (BMJ received the greatest number of responses (71% at level 5. A smaller number of respondents (56% rated Nursing Reference Centre (NRC at level 5. Clin-eguide received 59% of the responses at level 5, but it also received the greatest number of responses at the next highest level (level 4. Respondents rated all three databases similarly with regard to levels 1 and 2.Regarding how easy the resources were to learn, most respondents rated all three databases as easy to learn (BMJ, 77%; Clin-eguide, 72%; and NRC, 68%. Very few respondents

  19. DevOps for network function virtualisation: an architectural approach

    OpenAIRE

    Karl, H.; Draexler, S.; Peuster, M; Galis, A.; Bredel, M.; RAMOS, A.; Martrat, J.; Siddiqui, M S; Van Rossem, S.; Tavernier, W; Xilouris, G.

    2016-01-01

    The Service Programming and Orchestration for Virtualised Software Networks (SONATA) project targets both the flexible programmability of software networks and the optimisation of their deployments by means of integrating Development and Operations in order to accelerate industry adoption of software networks and reduce time-to-market for networked services. SONATA supports network function chaining and orchestration, making service platforms modular and easier to customise to the needs of di...

  20. Pilkupüüdev seltsidaam / Aare Ermel

    Index Scriptorium Estoniae

    Ermel, Aare, 1957-2013

    2006-01-01

    Shoti päritolu näitlejanna Lindsay Duncan, kes kehastab ajaloolises teleseriaalis "Rooma" (tootjad Ameerika HBO, inglaste BBC ja itaallaste RAI) Gaius Julius Caesari kättemaksuhimulist armukest Serviliat. Sama ka : Teleleht nr. 50, lk.38 : ill

  1. DevOps for the Urban IoT

    OpenAIRE

    Moore, John; Kortuem, Gerd; Smith, Andrew; Chowdhury, Niaz; Cavero, Jose; Gooch, Daniel

    2016-01-01

    Choosing the right technologies to build an urban-scale IoT system can be challenging. There is often a focus on low-level architectural details such as the scalability of message handling. In our experience building an IoT information system requires a high-level holistic approach that mixes traditional data collection from vendor-specific cloud backends, together with data collected directly from embedded hardware and mobile devices. Supporting this heterogeneous environment can prove chall...

  2. Einheitliches Auffinden, Erfassen und Ablegen von DevOps-Artefakten

    OpenAIRE

    Jonas, Thorsten

    2014-01-01

    In der heutigen Zeit sind Unternehmen darauf angewiesen, einerseits eine Vielzahl von Arbeitscomputern konfigurieren und andererseits ihre Server-Infrastruktur so skalieren zu können, dass durchgehend genügend Ressourcen zur Verfügung stehen. Gerade Web-Unternehmen, die Dienste im Internet anbieten, müssen ihre Server-Struktur so anpassen können, dass ihre Dienste auch bei stark steigenden Benutzerzahlen zur Verfügung stehen und dabei trotzdem schnell und stabil sind. Beide Aufgaben erfordert...

  3. Modelización genética de nódulos silíceos: aplicación al Devónico de Tabuenca (Cordillera Ibérica, España. I: Caracterización morfológica y composicional

    Directory of Open Access Journals (Sweden)

    Bona Artazos, M. E.

    2005-04-01

    Full Text Available Siliceous nodules of the Devonian deposits in the «Hoya Formation» (Tabuenca-Zaragoza have been studied. The nodules are included in lutites, and contain quartz, opaque minerals and clays. The cement is criptocrystalline quartz. Our morphologic study reveals that these are spheres and spheroids, with a gray colour and 0.3 to 9.6 cm of diameter, and grade into the direction of stratification. This spherical morphology is the result of isotropic structure of host sediment, and it indicates a growth mechanism by diffusion and a short transport mechanism. The existence of distorted lamination indicate that its central section was cemented before its outer section, and that its growth was passive, by a mechanism of porosity-grouth filling.Se han caracterizado morfológica y composicionalmente los nódulos silíceos que aparecen en los materiales pelíticos de la Formación Hoya (Devónico superior, en las proximidades de la localidad zaragozana de Tabuenca. Los nódulos se localizan entre capas de lutitas, y están compuestos por cuarzo criptocristalino, minerales arcillosos (caolinita principalmente, minerales opacos y restos fósiles. El estudio morfológico llevado a cabo revela que estas estructuras son esferas y esferoides, de color gris y con diámetro variable entre 0,3 y 9,6 cm. Además es destacable que se presentan con la misma orientación que la estratificación. Su morfología se explica producida por la estructura isótropa del sedimento hospedante, y ello indica que estas estructuras crecieron mediante un mecanismo de difusión y un transporte relativamente corto. La existencia de una laminación deformada alrededor de ellos mostraría que su parte central fue cementada, antes que la parte exterior, de manera pasiva mediante un mecanismo de crecimiento por relleno de porosidad.

  4. La susceptibilidad magnética del batolito de Achala (Devónico, Sierra Grande de Córdoba y sus diferencias con otros granitos achalianos The magnetic susceptibility of the Achala Batholith (Devonian, Sierra Grande de Córdoba and its difference with other Achalian granites

    Directory of Open Access Journals (Sweden)

    Silvana E. Geuna

    2008-09-01

    Full Text Available El magmatismo devónico de las Sierras Pampeanas de Córdoba y San Luis está representado por batolitos y plutones de composición monzogranítica y forma subelíptica, emplazados en un basamento metamórfico-plutónico eopaleozoico. Se distinguen dos grupos: el primero, compuesto por granitoides con hornblenda-biotita, metaluminosos a débilmente peraluminosos; y el segundo, formado por granitoides con biotita y muscovita, peraluminosos. Ambos grupos se caracterizan respectivamente por tener magnetita e ilmenita como fases accesorias, lo cual genera propiedades magnéticas distintivas. Entre ellos, el batolito de Achala, Córdoba, con una extensión de casi 2.500 km², es un buen exponente de los granitos paramagnéticos (no magnéticos. Su mineralogía magnética fue caracterizada en cuarenta y un sitios, la mayoría de ellos en el Monzogranito Achala. Se determinó una susceptibilidad magnética promedio muy baja, 15 x 10-5 (SI, controlada por el contenido de biotita e ilmeno- hematita. Veintiún sitios mostraron remanencia magnética estable portada por hematita, que aparece como un mineral accesorio, intercrecida con discos de exsolución de (hemoilmenita. La anisotropía de susceptibilidad magnética es débil y predominan las formas obladas, como es usual en fábricas magmáticas de granitos paramagnéticos; casi no se obtuvieron lineaciones. El grado de anisotropía es mayor en zonas con cizallamiento magmático, debido al efecto de la deformación subsolidus. El magnetismo débil del monzogranito de Achala contrasta con el carácter magnético de los plutones monzograníticos porfíricos más representativos de otros batolitos de la región, como Renca, Cerro Áspero y Las Chacras-Piedras Coloradas. La virtual ausencia de magnetita, junto con la presencia de ilmeno-hematita exsuelta, indica que un enfriamiento bajo condiciones oxidantes sería el responsable del carácter paramagnético de Achala. Como consecuencia de aplicación pr

  5. Computational Linguistics in the Netherlands 2004 : Selected papers from the fifteenth CLIN meeting

    NARCIS (Netherlands)

    Wouden, Ton van der; Poß, Michaela; Reckman, Hilke; Cremers, Crit

    2005-01-01

    This volume contains a selection of the papers presented at the fifteenth installment of Computational Linguistics in the Netherlands, held at Leiden University on Friday, December 17th, 2004. Organized by the computational linguists of what was at that time called the Leiden Centre for Linguistics

  6. Aircrew/Groundcrew Life Support Systems Research. Volume 1: CLIN 0001 Research Requirements

    Science.gov (United States)

    1993-07-01

    Barbara J. Stegmann, Dr. James T. Webb, and Ms. Janet F. Wiegman . The author cross-reference in Part D allows the reader to find the task report...following Technical Report. Krutz RW Jr, Nesthus TE, Scott WR, Webb JT, Noles CJ, Wiegman JF, Chavez RA, Eshaghian B. Aircrew life support systems...Beoch EL, Wiegman JF. Metabolic bases of +Gz-duration tolerance. 13th Annual Meeting of the IUPS Commission on Gravitational Physiology, Sept 1991, San

  7. Aircrew/Groundcrew Life Support Systems Research. Volume 2. CLIN 0002 Task Order Requirements

    Science.gov (United States)

    1993-07-01

    T. Webb, Dr. Lisa F. Weinstein, and Ms. Janet F. Wiegman . The author cross-reference in Part D allows the reader to find thw task report...exposures. B.13.2 Accomplishments The results of this effort are described in the following technical report. Wiegman JF, McLean SA, Olson RM, Pilmanis AA...Acquisition of physiological data during G-induced loss of consciousness (G-LOC). AL-TP-1992-0053. 1993:12pp. [T.O. 243 Wiegman JF, McLean SA, Olson RM

  8. Disease: H00103 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00103 Late complement pathway defects, including the following seven diseases: C5 ...Current perspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:22...rstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: a

  9. Disease: H00086 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00086 Hyper IgM syndromes, autosomal recessive type, including the following three diseases...tives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:18424339 (gene) Morra M, ...er A, Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases

  10. Disease: H00087 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00087 Other humoral immunodeficiencies, including the following three diseases: Im...MeSH: C537362 PMID:11058677 (description, gene) Buckley RH. Primary immunodeficiency diseases due to defects...win ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immun...C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of Immunol

  11. Disease: H00089 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00089 IFN-gamma/IL-12 axis, including the following five diseases: IL-12 p40 subun...rrent perspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:18424339 (ge...R, Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of Immunological So

  12. Disease: H00098 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00098 Chronic granulomatous disease, including the following four diseases: X-link...65 Kumar A, Teuber SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immu...ifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of I

  13. Disease: H00104 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00104 Alternative complement pathway component defects, including the following four diseases...primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:17952897 (gene) Geha RS, Notarange...hs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases: an update from the Intern

  14. Recommendation on mean molar activity coefficients and single ion activity coefficients of solutions for calibration of ion-selective electrodes for sodium, potassium and calcium determination (Reprinted from J Clin Chem Clin Biochem)

    NARCIS (Netherlands)

    Burnett, RW; Covington, AK; FoghAndersen, N; Kulpmann, WR; Maas, AHJ; MullerPlathe, O; SiggaardAndersen, O; VanKessel, A; Wimberley, PD; Zijlstra, WG

    1997-01-01

    In principle, flame photometry measures substance concentration, and ion-selective electrodes (ISEs) measure ion activity. However, the situation regarding the comparison of results from the two techniques when applied to blood plasma is complex. The problem can be approached experimentally from the

  15. What Clinical Interventions Have Been Implemented to Prevent or Reduce Postpartum Hypertension Readmissions? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Sara O'Meara

    2016-08-01

    Full Text Available A literature review was conducted to determine what clinical interventions have been studied and implemented to prevent and/or reduce postpartum hypertension readmissions. Appropriate verbal and printed educational materials should be given to the patient prior to discharge with use of the “teach back” method. Patients and health care providers within the multidisciplinary team should be educated on the warning signs and symptoms of worsening hypertensive disease and when to appropriately involve the obstetrician. The use of text messaging may be useful in preventing hospital readmissions by increasing patient follow-up and compliance and appropriately managing patients in the postpartum period. Treating postpartum patients with furosemide may decrease blood pressure and prevent postpartum hypertension and the need for antihypertensive therapy.

  16. Computational Linguistics in the Netherlands 1996. Papers from the CLIN Meeting (7th, Eindhoven, Netherlands, November 15, 1996).

    Science.gov (United States)

    Landsbergen, Jan, Ed.; Odijk, Jan, Ed.; van Deemter, Kees, Ed.; van Zanten, Gert Veldhuijzen, Ed.

    Papers from the meeting on computational linguistics include: "Conversational Games, Belief Revision and Bayesian Networks" (Stephen G. Pulman); "Valence Alternation without Lexical Rules" (Gosse Bouma); "Filtering Left Dislocation Chains in Parsing Categorical Grammar" (Crit Cremers, Maarten Hijzelendoorn);…

  17. Droit, travail et passion, dans les restructurations : le déclin de l'engagement au travail

    OpenAIRE

    Didry, Claude

    2011-01-01

    Au-delà de la passion, le travail salarié, c'est-à-dire fondé sur le contrat de travail se définit par un engagement d'une double nature, engagement individuel vis-à-vis de l'emploi, engagement dans la division du travail sur le lieu de travail. Comment les restructurations comme décisions économiques donnant lieu à suppressions d'emplois touchent-elles et révèlent-elles cette dimension d'engagement? Après avoir envisagé les avancées de la jurisprudence sur les plans sociaux dans les années 1...

  18. Émergence et déclin de la gouvernance démocratique en droit international

    NARCIS (Netherlands)

    J. d' Aspremont

    2009-01-01

    This article argues that the years 1989-2010 can be hailed as an unprecedented epoch of international law during which domestic governance - understood here in a traditional way as the use of public authority at the domestic level through a central governmental authority - came to be regulated to an

  19. Disease: H01362 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 0: L13.0 PMID:22811741 (gene, env_factor) Nakajima K Recent advances in dermatitis herpetiformis. Clin Dev I..., Hissa-Elian A, de Abreu MA, Goncalves VS Review: dermatitis herpetiformis. An Bras Dermatol 88:594-9 (2013...76 (drug) Caproni M, Antiga E, Melani L, Fabbri P Guidelines for the diagnosis and treatment of dermatitis herpetiformis. J Eur Acad Dermatol Venereol 23:633-8 (2009) ...

  20. Disease: H00516 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available els. Curr Top Dev Biol 84:37-138 (2008) PMID:15917202 (gene, env_factor) Jugessur A, Murray JC Orofacial cle...PMID:12030886 (gene, env_factor) Murray JC Gene/environment causes of cleft lip and/or palate. Clin Genet 61...K, Deleyiannis FW, de Salamanca JE, Vieira AR, Lidral AC, Martin JF, Murray JC Mutations in BMP4 are associa

  1. Disease: H00100 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00100 Neutropenic disorders, including the following three diseases: Kostmann synd...rspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMID:15096561 Lim MS, Ele...ME, Fischer A, Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases...D:19811314 Rezaei N, Moazzami K, Aghamohammadi A, Klein C Neutropenia and primary immunodeficiency diseases. Int Rev Immunol 28:335-66 (2009) ...

  2. Disease: H00105 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00105 Mannose-binding lectin pathway component defects, including the following two diseases...ering MC, Wurzner R, Tedesco F Complement in human diseases: Lessons from complement deficiencies. Mol Immun... Kumar A, Teuber SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immuno...imary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary I..., Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Pr

  3. Disease: H00106 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00106 Complement regulatory protein defects, including the following six diseases:...(description, gene) Botto M, Kirschfink M, Macor P, Pickering MC, Wurzner R, Tedesco F Complement in human diseases...ershwin ME. Current perspectives on primary immunodeficiency diseases. Clin Dev Immunol 13:223-59 (2006) PMI...her A, Hammarstrom L, Nonoyama S, Ochs HD, Puck JM, Roifman C, Seger R, Wedgwood J. Primary immunodeficiency diseases

  4. The DevOps 2.0 toolkit automating the continuous deployment pipeline with containerized microservices

    CERN Document Server

    Farcic, Viktor

    2016-01-01

    This book is about different techniques that help us architect software in a better and more efficient way with microservices packed as immutable containers, tested and deployed continuously to servers that are automatically provisioned with configuration management tools. It's about fast, reliable and continuous deployments with zero-downtime and ability to roll-back. It's about scaling to any number of servers, design of self-healing systems capable of recuperation from both hardware and software failures and about centralized logging and monitoring of the cluster.In other words, this book envelops the whole microservices development and deployment lifecycle using some of the latest and greatest practices and tools. We'll use Docker, Kubernetes, Ansible, Ubuntu, Docker Swarm and Docker Compose, Consul, etcd, Registrator, confd, and so on. We'll go through many practices and even more tools. Finally, while there will be a lot of theory, this is a hands-on book. You won't be able to complete it by reading it ...

  5. Net-centric ACT-R-Based Cognitive Architecture with DEVS Unified Process

    Science.gov (United States)

    2011-04-01

    effort has been spent in analyzing various forms of requirement specifications, viz, state-based, Natural Language based, UML-based, Rule- based, BPMN ...requirement specifications in one of the chosen formats such as BPMN , DoDAF, Natural Language Processing (NLP) based, UML- based, DSL or simply

  6. Pro website development and operations streamlining DevOps for large-scale websites

    CERN Document Server

    Sacks, Matthew

    2012-01-01

    Pro Website Development and Operations gives you the experience you need to create and operate a large-scale production website. Large-scale websites have their own unique set of problems regarding their design-problems that can get worse when agile methodologies are adopted for rapid results. Managing large-scale websites, deploying applications, and ensuring they are performing well often requires a full scale team involving the development and operations sides of the company-two departments that don't always see eye to eye. When departments struggle with each other, it adds unnecessary comp

  7. CloudWave: where adaptive cloud management meets DevOps

    OpenAIRE

    Bruneo, Dario; Fritz, Thomas; Keidar-Barner, Sharon; Leitner, Philipp; Longo, Francesco; Marquezan, Clarissa; Metzger, Andreas; Pohl, Klaus; Puliafito, Antonio; Raz, Danny; Roth, Andreas; Salant, Eliot; Segall, Itai; Villari, Massimo; Wolfsthal, Yaron

    2014-01-01

    The transition to cloud computing offers a large number of benefits, such as lower capital costs and a highly agile environment. Yet, the development of software engineering practices has not kept pace with this change. The design and runtime behavior of cloud based services and the underlying cloud infrastructure are largely decoupled from one another, which limits both the efficiency of the cloud environment and the Quality of Service which can be delivered to the hosted applications. This ...

  8. A low-cost, arduino-like dev-kit for single-element ultrasound imaging

    CERN Document Server

    Jonveaux, Luc

    2016-01-01

    Ultrasound imaging is developing an open-source ecosystem, especially for software frameworks. Little exists on the open-hardware side. Hence a focus was put on producing easy-to-use technological (hardware and software) kit to allow anyone - scientists, academics, hackers, makers to have a experimental setup for ultrasound imaging at a low cost, at home, with no specific equipment required. To this end, open source, arduino-like modules have been developed to build a simple, but complete, single channel analog front-end system, where all intermediary signals are readily accessible by the user. A single-channel architecture allows to avoid the beam-forming head, though it limits the quality of the image obtained, and brings robustness to the system. Moreover, complex RF processing, being shifted to the analog side, limits the quality of the final image. These were tested with re-purposed ultrasound mechanical scanner heads, as well as re-purposed medical imaging transducers, and provided interesting images. M...

  9. Concepts for integrating DevOps methodologies with model-driven cloud management based on TOSCA

    OpenAIRE

    Wettinger, Johannes

    2012-01-01

    The paradigm of Cloud computing introduces new approaches to manage IT services and applications. Those approaches overcome traditional IT infrastructure and service management. One of the main goals of Cloud computing is to automate the whole management of IT services in order to reduce costs and to make the execution of management tasks less error-prone. To make this happen, Cloud providers offer proprietary tools to create and manage services in the Cloud. However, when services get more c...

  10. Dev hücreli fibroma ile ilgili olgu raporu ve güncelleme

    OpenAIRE

    Madi, Medhini; Ram Shetty, Shishir; Subhas G Babu; Achalli, Sonika

    2014-01-01

    The giant cell fibroma is a fibrous tumour with a distinctive clinicopathologic features which sets it apart from a conventional fibroma. It represents approximately 2% to 5% of all oral fibrous proliferations submitted for biopsy and is found predominantly in Caucasians and rarely in other races. Most often giant cell fibroma is mistaken for papilloma because of its papillary surface or fibroma because of its fibrous or elastic nature. Here, we report a case of giant cell fibroma, in the reg...

  11. Hodin J. 2000. Plasticity and constraints in development and evolution. J exp zool (Mol dev evol) 288:1-20

    Science.gov (United States)

    Kourakis; Martindale

    2000-08-15

    The sentences on page 8, in paragraph 2 of column 2 reads: In the short-germ insects, typified by Drosophila melanogaster, all the segments are specified nearly simultaneously in a noncellular, syncitial environment (reviewed in Lawrence, '92). By contrast, in the long-germ insects, typified by the grasshopper Schistocerca, the segments are specified in a gradual anterior-to-posterior progression in a cellular environment (reviewed in Patel, '94; Tautz et al., '94). The sentences should read: In the long-germ insects, typified by Drosophila melanogaster, all the segments are specified nearly simultaneously in a noncellular, syncitial environment (reviewed in Lawrence, '92). By contrast, in the short-germ insects, typified by the grasshopper Schistocerca, the segments are specified in a gradual anterior-to-posterior progression in a cellular environment (reviewed in Patel, '94; Tautz et al., '94). The terms "long-germ" and "short-germ" were reversed. The germ-type classification is key to the point being made in this paragraph: namely, showing that a similar-looking segmental plan can be formed by two rather different ontogenetic routes. The author regrets the error.

  12. Drug education in victorian schools (DEVS: the study protocol for a harm reduction focused school drug education trial

    Directory of Open Access Journals (Sweden)

    Midford Richard

    2012-02-01

    Full Text Available Abstract Background This study seeks to extend earlier Australian school drug education research by developing and measuring the effectiveness of a comprehensive, evidence-based, harm reduction focused school drug education program for junior secondary students aged 13 to 15 years. The intervention draws on the recent literature as to the common elements in effective school curriculum. It seeks to incorporate the social influence of parents through home activities. It also emphasises the use of appropriate pedagogy in the delivery of classroom lessons. Methods/Design A cluster randomised school drug education trial will be conducted with 1746 junior high school students in 21 Victorian secondary schools over a period of three years. Both the schools and students have actively consented to participate in the study. The education program comprises ten lessons in year eight (13-14 year olds and eight in year nine (14-15 year olds that address issues around the use of alcohol, tobacco, cannabis and other illicit drugs. Control students will receive the drug education normally provided in their schools. Students will be tested at baseline, at the end of each intervention year and also at the end of year ten. A self completion questionnaire will be used to collect information on knowledge, patterns and context of use, attitudes and harms experienced in relation to alcohol, tobacco, cannabis and other illicit drug use. Multi-level modelling will be the method of analysis because it can best accommodate hierarchically structured data. All analyses will be conducted on an Intent-to-Treat basis. In addition, focus groups will be conducted with teachers and students in five of the 14 intervention schools, subsequent to delivery of the year eight and nine programs. This will provide qualitative data about the effectiveness of the lessons and the relevance of the materials. Discussion The benefits of this drug education study derive both from the knowledge gained by trialling an optimum combination of innovative, harm reduction approaches with a large, student sample, and the resultant product. The research will provide better understanding of what benefits can be achieved by harm reduction education. It will also produce an intervention, dealing with both licit and illicit drug use that has been thoroughly evaluated in terms of its efficacy, and informed by teacher and student feedback. This makes available to schools a comprehensive drug education package with prevention characteristics and useability that are well understood. Trial registration Australia and New Zealand Clinical Trials Register (ANZCTR: ACTRN12612000079842

  13. Ayak Küboid Kemiğinde Lokalize Dev Hücreli Tümör

    OpenAIRE

    Yazicioglu, O.; Kokino, M.; Temelli, Y.; Tozun, R.; Domanic, U.; Turkmen, M.; Ozger, H.

    2004-01-01

    Attempts have been made to review 36 giant cell tumours treated surgicaly in the Department of Orthopaedics and Traumotology of the İstanbul Medical School of İstanbul Universty, beetween 1970-1983 years and after making researchs in literature it has been found conviniend to report a giant cell tumour localized in cuboid bone of the foot as it is seen the first time both in literature and among our clinical cases.

  14. Patrons d'administració de sistemes en entorns DevOps

    OpenAIRE

    Monpeat Santo, Frederic

    2015-01-01

    El següent article pretén analitzar les tasquesd'un administrador, veure si es poden identificar patrons comuns que es puguin aplicar a la automatització en grans infraestructures i presentar la seva implementació en Python. El siguiente artículo pretende analizar las tareas de un administrador, ver si se pueden identificar patrones comunes que se puedan aplicar a la automatización en grandes infraestructuras y presentar su implementación en Python. Master thesis for the Free Soft...

  15. Principios, roles y métricas en alineamiento estratégico de nuevos requerimientos utilizando DevOps

    OpenAIRE

    Belalcázar, Alberto; Díaz, Francisco Javier; Molinari, Lía; Rodríguez, Christian Adrián

    2016-01-01

    En un entorno de usuarios cada vez más exigentes y ansiosos de los servicios que les brinda la tecnología, las áreas de tecnología de la información y las comunicaciones (TICs) adquieren un papel estratégico en las organizaciones debido al apoyo y aporte que brindan a los usuarios. Las aplicaciones que utiliza cotidianamente, en forma ubicua, obliga a las áreas de TICs a dinamizar y acelerar los modelos tradicionales de desarrollo y entrega de aplicaciones, con estrategias que logren disminui...

  16. L’essor et le déclin de la stratégie économique keynésienne – structuraliste au Mexique

    OpenAIRE

    López G., Julio

    2012-01-01

    Pendant au moins deux décennies après la seconde guerre mondiale, la croissance économique au Mexique a été très rapide, à tel point que pour la caractériser, le terme « miracle mexicain » a été introduit. Le but de ce travail est d’étudier les causes immédiates ainsi que les origines historiques de l’essoufflement du miracle mexicain. L’auteur examine les limites de la stratégie fondée sur la substitution des importations en prenant en compte aussi bien des problèmes du côté de l’offre que d...

  17. 1. Le commerce à la valise roumain : un phénomène en déclin ?

    OpenAIRE

    Gangloff, Sylvie; Pérouse, Jean-François

    2014-01-01

    L’expression « commerce à la valise » (bavul ticareti / suitcase turizm) désigne l’activité des individus qui, à titre personnel, en groupe, en couples ou seuls, se rendent à İstanbul pour y effectuer de multiples achats, généralement dans le textile et le cuir (vestes en cuir, chaus­sures, tee-shirts, etc.), dans la confiserie (bis­cuits, chewing-gums) et les produits d’entre­tiens (savons). De retour dans leur pays, ces commerçants revendent ces marchandises sur des marchés, à des commerçan...

  18. [Nutrition and child development II; a comparison of physical development in two school children groups with different income level (Rev Clin Esp 1944; 12:155-164) ].

    Science.gov (United States)

    Grande Covián, F; Rof Carballo, J; Jiménez García, F

    2014-09-01

    El estudio comparativo de dos grupos de niños en edad escolar y de nivel económico diferente demuestra que los que pertenecen a un suburbio madrileño económicamente pobre sufren un retraso en el crecimiento que se caracteriza por una talla y un peso inferiores en relación con la edad. El retraso del peso corporal es proporcionalmente mayor al de la talla. Cuando se calcula según WETZEL la edad que teóricamente corresponde al desarrollo corporal de estos niños se observa un retraso de 2,94 años para una edad término medio de 10,14 años. El retraso global del desarrollo somático representa por tanto el 29 por 100 de la edad cronológica media. Este retraso en el desarrollo debe atribuirse principalmente a causas dietéticas y no solo a carencias específicas, sino sobre todo a insuficiencia cuantitativa en la dieta consumida. Desde el punto de vista cualitativo es probablemente la falta de leche en la dieta uno de los más importantes factores en la génesis de este trastorno del desarrollo.

  19. Computational Linguistics in the Netherlands 12 January 2007, Leuven : Proceedings of the 17th Meeting of Computational Linguistics in the Netherlands (CLIN17)

    NARCIS (Netherlands)

    Dirix, Peter; Schuurman, Ineke; Vandeghinste, Vincent; Van Eynde, Frank

    2007-01-01

    This volume contains a selection of the papers presented at the seventeenth installment of the Computational Linguistics in the Netherlands conference, held at the Katholieke Universiteit Leuven on Friday, January 12th, 2007. It was organized by the Centre for Computational Linguistics and featured

  20. [Nutrition and child development I; nutritional status of school children in a peripheral district of Madrid (Rev Clin Esp 1944; XII:87-94)].

    Science.gov (United States)

    Grande Covián, F; Rof Carballo, J; Jiménez García, F; Morata Cernuda, A

    2014-09-01

    El estudio clínico del estado nutritivo de un grupo de niños en edad escolar, habitantes de un suburbio madrileño revela la existencia, relativamente rara, de signos carenciales específicos, que contrasta vivamente con el considerable retraso que se observa en su desarrollo somático. Los hechos parecen demostrar que el problema nutritivo de estos niños es sobre todo un problema cuantitativo. El retraso de la evolución está en relación con la insuficiencia global de la dieta y con el déficit de calcio que es probablemente el elemento individual con mayor grado de carencia en las dietas. La anemia que presenta el 98% de los niños no parece deberse únicamente a una deficiencia de hierro porque la dieta parece tener una cantidad adecuada; probablemente esté más en relación con el exiguo contenido de proteínas animales de la ración.

  1. Barrages de tufs calcaires et cascades dans le Centre-Var : rapport avec les eaux des sources karstiques, historique et déclin actuel

    Directory of Open Access Journals (Sweden)

    Jean Nicod

    2010-03-01

    Full Text Available Dans les vallées de l'intérieur de la Provence, de grandes accumulations de tufs et de travertins sont liées aux sources karstiques importantes. En rapport avec l'évolution géomorphologique, les travertins anciens forment des balcons et des terrasses. La période récente de grande construction travertineuse débute souvent au Préboréal et se généralise dans l'Atlantique. Au cours du Néolithique final, cette sédimentation décroît en fonction de la détérioration climatique et de la déforestation liée à la pression anthropique. Cependant quelques barrages (dômes stromatolitiques et marais, avec dépôts de tourbes, persistent jusqu'à l'âge historique. Dans le Centre-Var, les dépôts de tufs restent actifs dans quelques sites refuges, dans les hautes vallées forestières, proches des sources karstiques, et sur quelques grandes cascades. De plus, le long des rivières, des cascades à tufs sont issues des aménagements de moulins et de canaux d'irrigation.La sédimentation des tufs dépend de nombreux facteurs en interaction, dont :- la minéralisation carbonatée des eaux des sources karstiques,- le régime hydrologique saisonnier,- l'écosystème régional et local (forêts, ripisylves,- le biotope algo-bryophytique.De nos jours, la sédimentation stromatolitique est en situation critique du fait de l'impact de multiples facteurs en rapport avec l'accroissement de l'urbanisation et les changements environnementaux :- pollution, accroissement de la turbidité sur les petits affluents résultant de l'agriculture mécanisée,- diminution drastique des débits dans les saisons de printemps-été, où l'activité algo-bryophytique est la plus favorable, du fait de l'augmentation générale des prélèvements.La période de sécheresse récente (2006-2008 a accentué ces impacts sur les barrages de tufs. Et la protection de ces sites de grand intérêt environnemental et patrimonial pose des problèmes complexes.In the valleys of inner Provence, numerous travertine formations are wide extension in relation with important karstic springs. Because the geomorphological evolution, the old travertines are maked up balconies and terraces. The recent period of main travertine construction begins as far back as in the Preboreal (even in Bölling at southern Luberon and appears generalized in the Atlantic. In the late Neolithic (around 4000 BP, this sedimentation decreases with the climatic deterioration and the opening of forest cover under the weight of human pressure. However some tufa dams (stromatolite doms and associated wetland with peat deposits continues up to the historic times. In the Middle Var County, these tufa deposits on the dams remains active in some refuge sites, in the upper and woody valleys, near the karstic springs, and in any high waterfalls. More along the rivers, some waterfalls with tufa deposits proceeds from the old mills and irrigation canal fitting. This tufa sedimentation is in relation with the interference of multiple factors, whose:- carbonate mineralization of the karstic springs,- seasonal working of the hydrosystem,- regional and local ecosystem (forested land, important riparian cover,- algo-bryophitic biotope.Nowadays, the stromatolitc sedimentation is in critical situation because the impact of multiple factors in relation with increased urbanization and environmental change:- river pollution, increased turbidity in little tributaries flowed from agricultural mecanization,- decreased flow in seasonable times (spring - summer, the most favourable to the algo-bryophytic activity, because the common increasing water sample.The recent drought period (2006-2008 has maked worse these impacts on the tufa dams. And the protection of these sites of large environmental and patrimonial interest put complex problems.

  2. Les chaîniers français (1823-2005. De l’essor au déclin

    Directory of Open Access Journals (Sweden)

    Edgard Strigler

    2011-05-01

    Full Text Available Composition du juryMonsieur Marc de Beauregard, PDG de Sedis de 1991 à 1993,Monsieur Michel Cotte, professeur émérite, Université de Nantes,Monsieur Alain Dewerpe, directeur d’études, ÉHESS,Monsieur Patrick Fridenson, directeur de thèse, directeur d’études, ÉHESS,Monsieur Hervé Joly, directeur de recherche, CNRS,Monsieur Pierre Lamard, professeur, ,Université de Technologie de Belfort-Montbéliard,Monsieur Denis Woronoff, professeur émérite, Université de Paris I.Thèse soutenue le 20 janvier 2...

  3. Association Between Organizational Citizenship Behavior and Educational Performance of Faculty Members in Tabriz University of Medical Sciences- 2014 [Res Dev Med Educ 2015;4(1:81-84

    Directory of Open Access Journals (Sweden)

    Asadullah Khadivi

    2015-12-01

    Results: There was a significant relationship between altruism and educational performance (P =0.043. There was a significant relationship between conscientiousness and educational performance (p=0.046. A significant relationship was observed between sportsmanship and educational performance (p=0.004. There was no significant relationship between civic virtue and educational performance (p=0.98. A significant relationship was observed between respect and educational performance (P>0.001. There was no relationship between citizenship behavior and gender of the faculty members (P> 0.05. Conclusion: The results of this study showed that the more faculty members have the spirit of cooperation and assistance to colleagues and students and try to understand the specific situations that students face, the more effective they are in increasing the educational performance at the university level.

  4. Commentary on "The Evolutionary Origin of Female Orgasm" by M. Pavlicev and G. Wagner, 2016, J. Exp. Zool. (Mol. Dev. Evol.) 326(6):326-337.

    Science.gov (United States)

    Komisaruk, Barry R

    2016-12-01

    Evidence is presented as an alternative to the authors' claims that in the course of evolution, a link between orgasm and ovulation has been lost in women, that evolutionary changes in clitoral anatomy underlie this loss, and that women's orgasm plays no significant role in reproduction.

  5. Fruits of Knowledge: Polemics, Humour and Moral Education in the Writings of Rokeya Sakhawat Hossain, Lila Majumdar and Nabaneeta Dev Sen

    NARCIS (Netherlands)

    Bagchi, B.

    2014-01-01

    This paper analyses literary sources, by three women writing in Bengali, from c.1900 to contemporary times. These writings offer far more complex, heterogeneous, innovative and creative strategies for the shaping, reform and moral education of subjects, than have hitherto been recognised. Authors fo

  6. XtraReports报表高级用法——DevExpress For VS.NET高级技巧系列(六)

    Institute of Scientific and Technical Information of China (English)

    李福红

    2012-01-01

    XtraReports是开发的新一代适用于Windows.NET和ASP.NET开发的控件.XtraReports 组件可以整合于Visual Studio IDE之中,带来更高的动作效率,同时,对于应用软件和网站报表发布它具有更大的灵活性.

  7. Karşı taraf böbrek fonksiyonu kötü olan bir dev böbrek taşı olgusu

    OpenAIRE

    2009-01-01

    Giant renal calculus is rarely seen in urologic practice. A 69-year-old woman who had right giant renal calculus with poorly functioning opposite kidney is presented. She was with a history of right pyelolithotomy for large renal calculus 10 years back. Ultrasonography(USG), uncontrast computed tomography ( CT ), plain abdominal X-ray ( KUB ) and intraveneous urography ( IVU ) revealed a giant renal calculus (10 x 8 cm) and grade III hydronephrosis on the right kidney and moderate calixiel di...

  8. In Adult Smokers Unwilling or Unable to Quit, Does Changing From Tobacco Cigarettes to Electronic Cigarettes Decrease the Incidence of Negative Health Effects Associated With Smoking Tobacco? A Clin-IQ

    Directory of Open Access Journals (Sweden)

    Jennifer Brown

    2014-05-01

    Full Text Available Data from a randomized controlled trial and systematic review support the claim that switching from tobacco cigarettes to electronic cigarettes (e-cigarettes can reduce the short-term negative health effects of smoking. In adult smokers unwilling or unable to quit, exhaled carbon monoxide levels, total number of cigarettes smoked, and exposure to nitrosamine chemicals were reduced within a 12-month period. While the e-cigarette industry remains largely unregulated thus far, these studies provide encouraging hope in the uphill battle toward helping patients make informed and healthy choices.

  9. Alimentación y desarrollo infantil I: el estado nutritivo de los niños en edad escolar de un suburbio madrileño (Rev Clin Esp 1944; XII:87-94

    Directory of Open Access Journals (Sweden)

    F. Grande Covián

    Full Text Available El estudio clínico del estado nutritivo de un grupo de niños en edad escolar, habitantes de un suburbio madrileño revela la existencia, relativamente rara, de signos carenciales específicos, que contrasta vivamente con el considerable retraso que se observa en su desarrollo somático. Los hechos parecen demostrar que el problema nutritivo de estos niños es sobre todo un problema cuantitativo. El retraso de la evolución está en relación con la insuficiencia global de la dieta y con el déficit de calcio que es probablemente el elemento individual con mayor grado de carencia en las dietas. La anemia que presenta el 98% de los niños no parece deberse únicamente a una deficiencia de hierro porque la dieta parece tener una cantidad adecuada; probablemente esté más en relación con el exiguo contenido de proteínas animales de la ración.

  10. 亚麻籽能改善绝经妇女的血脂,但对骨代谢无作用[英]/Lncas E…∥J Clin Endocrinol Metab.

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    亚麻籽富含木脂素类,这是一类植物雌激素。由于它对人类健康有益,故已成为人类的饮食成分。据报道,植物雌激素能降低血清胆固醇水平,以及具雌激素样、抗雌激素样和抗氧化活性。鉴于木脂素类与雌激素的结构类似,以及雌激素能有效地防止绝经妇女的骨质丢失,作者用亚麻籽进行了一项随机、双盲、平行对照的临床试验,以验证亚麻籽是否有益于骨骼健康。

  11. Computer-Based Training of Cannon Fire Direction Specialists

    Science.gov (United States)

    1993-01-01

    Tramining Prgms, John D. Winlder, Stephen J. Kirin, and John S. Uebersax, 1992. N-3527-A, Te Army Miitary Oxuvatioal Specity Databse , Stephen J. Kirin and...raning tasks 187 Determine and announce fire commands for prearranged fires -1.196 188 Compute firing data manually for todc chemical projectile -1.458 189...187 Perform operator’s PMCS on SB-22 PT switchboards -1.4547 188 Compute firing data manually for toxic chemical -1.4575 projectile 189 Determine firing

  12. Proposição para adaptação de termos do CMMI-DEV 1.3 para aplicação em PDPS de empresas de manufatura

    OpenAIRE

    2014-01-01

    Com um mercado global cada vez mais agressivo e competitivo, as indústrias têm buscado meios para se manterem competitivas. O Processo de Desenvolvimento de Produtos (PDP) ocupa um importante papel na estratégia das empresas que buscam um diferencial competitivo. Entretanto, para um PDP se tornar um diferencial competitivo, ele deve apresentar um patamar mínimo de maturidade, que representa o seu potencial de crescimento de capacitação, a riqueza do processo da organização e a consistência co...

  13. Response to Ponamgi et al. Comments on Khalighi et al. Takotsubo Cardiomyopathy: A Long Term Follow-up Shows Benefit with Risk Factor Reduction. J. Cardiovasc. Dev. Dis., 2015, 2, 273–281.

    Directory of Open Access Journals (Sweden)

    Mohammad Umar Farooq

    2016-01-01

    Full Text Available We appreciate the thorough response given by Ponagmi et al. [1], who rightly point out that the pathophysiology and modifiable risk factors of Takotsubo Cardiomyopathy (TC have yet to be unequivocally established. [...

  14. A Studty on the Inte gr ar ted Dev leop ment of the Cul tural T ourism of Southern Jiangxi Province%赣南文化旅游整合开发研究

    Institute of Scientific and Technical Information of China (English)

    熊文平

    2016-01-01

    Abts rcat :Although the cultural tourism of southern Jiangxi Province has been developing rapidly , we fail to exploit it from every perspective , which causes some problems , such as the less outstanding overall theme image of this tourism, the unreasonable designs of travel routes , and single travel product and so on .As a result, its com-prehensive function cannot be revealed .This paper , starting with analysis on the realistic possibility and necessity of the resource consolidation of southern Jiangxi Province tourism , further to advocate strategies so that we can en-hance the market competition of the tourism , attract more people to visit the target area , and promote the compre-hensive strength of the Soviet Area of southern Jiangxi Province .%近年来赣南文化旅游快速发展,但还没能很好地从整体着眼赣南文化旅游开发,造成赣南文化旅游主题整体形象不够突出、旅游线路设计不合理、旅游产品单一等问题,从而不能凸显赣南文化旅游整体功效。分析赣南旅游资源整合的现实可能性和必要性,认为赣南文化旅游整合开发的策略应体现在以下方面:整合开发资源,加大文化融合力度;整合资源空间突破行政界线;整合品牌形象,提升知名度;整合旅游线路,丰富产品层次。这样才能增强赣南旅游市场竞争力,吸引更多的游客来赣南旅游观光休闲,提升赣南老区综合实力。

  15. Letters To The Editor: Rebuttal to Ottomanelli et al. Methods of a multisite randomized clinical trial of supported employment among veterans with spinal cord injury. J Rehabil Res Dev. 2009;46(7:919-30.

    Directory of Open Access Journals (Sweden)

    Marcel Dijkers, PhD

    2010-07-01

    Full Text Available Probably no fashion has gripped first medicine; then the rest of health care; and finally social services, vocational rehabilitation, education, and other professional fields as quickly and deeply as evidence-based practice (EBP. There have been claims that there is nothing new here, that professionals have always been required to base treatment of their patients/clients on evidence as to what are effective, efficient, and reliable methods of diagnosing/assessing, treating, or offering prognosis, and have done so. However, the core message of EBP has been a worthwhile one whatever one thinks of that claim: not any odd piece of evidence will do. To provide patients/clients with optimal service, one needs to base it on a systematic study of the most recent and most appropriate evidence, carefully evaluated for potential biases and errors. Probably as a result of the prominence of the originators of EBP in medicine, as well as the appealing and easy quantitative and mathematical approaches to evidence evaluation, EBP is now a bandwagon few people dare to disdain publicly. In fact, adding the label "evidence-based" to about anything and everything done professionally is seen as a way of giving it a modern, up-to-date, scientific cachet that will appeal to other professionals, if not patents/clients. EBP has become a holy cow to whom tribute is due.

  16. Rebuttal to McAleer J. Mobility redux: Post-World War II prosthetics and functional aids for veterans, 1945 to 2010. J Rehabil Res Dev. 2011;48(2:vii-xvi.

    Directory of Open Access Journals (Sweden)

    Stewart M. Coulter, PhD

    2011-07-01

    Full Text Available Dear Editor:This letter addresses the following sentence in the "Mobility redux: Post-World War II prosthetics and functional aids for veterans, 1945 to 2010" editorial that appeared in JRRD, Volume 48, Number 2. The sentence on page xv, second column: "Early testing and rigorous subject feedback clearly showed that DEKA II's first active socket design was not what patients wanted or needed." is not accurate. There is evidence in the historical literature on problematic prosthetic sockets. However, user response to the interface design introduced as part of the DEKA Arm System in collaboration with prosthetists at biodesigns, Inc (Santa Monica, California and Next Step Orthotics and Prosthetics, Inc (Manchester, New Hampshire has been quite favorable.It would be accurate to say "Early testing and rigorous subject feedback clearly showed that the active socket design used as part of the DEKA Arm System offers significant benefits and was positively received by research subjects."

  17. The development of [得 DE+V] and [V +得 DE]constructions in the Hunan dialects%湖南方言“得+V”和“V+得”结构的发展

    Institute of Scientific and Technical Information of China (English)

    伍云姬

    2001-01-01

    得DE"to obtain"is a linguistic sign which has a long history and has very complex usages.This paper will focus on the development of[DE+V]and[V+DE]constructions in which both the DE are Claimed to be used as modal auxiliaries and indicate the notion of possibilities in Chinese throughout the history.[DE+V]appeared earlier than[V+DE](Yue Junfa,1984,Yang Ping,1989,Sun Chaofen 1996,among others).Both constructions are rarely used in Mandarin but are till active in the Hunan dialects.The data in Hunan dialects show that[DE+V]and [V+DE]constructions do not only indicate possibilities,and even when the two constructions both indicate possibilities,they are not identical and not always interchangeable.In the Hunan dialects,the following contrasts between these two constructions can be found:[DE+V][V+DE] Volition Abiloty Possibility Permission Obligation Possibility In this paper,the different usages across localities in Hunan will examined, and the hypothesis of the order differences and the path of development will be stressed.This paper will concentrate on the [DE+V]and [V+DE]constructions.The focus will be on the semantic contrasts of these two constructions in which the word orders are opposite in the Hunan dialects,as well as the hypothesis of the paths of development of the two constructions.

  18. The application of low angle light scattering to evaluate qualitatively and quantitatively the dynamics of formation of oligomers in heme protein sensors

    Science.gov (United States)

    Sabino, Luis G.; Guimarães, Wellinson Gadelha; Costa, Pedro Mikael; Carepo, Marta S. P.; Gondim, Ana C. S.; Lopes, Luiz G. F.; Sousa, Eduardo H. S.

    2016-03-01

    The aim of this study is to investigate the structural organization and oligomerization properties of the sensory kinase protein DevS using low-angle light scattering (LALS) and gel filtration chromatography (HPLC). In addition, the structural characteristics of FixL and BSA were investigated and compared with DevS to better elucidate LALS technique. DevS is a direct and specific O2 sensing protein in Mycobacterium tuberculosis and acts as an activator of the transcription factor protein DevR. This latter triggers the latency state of tuberculosis under hypoxic conditions. DevS has been briefly evaluated under different conditions of concentration, ionic strength and temperature. LALS and gel filtration (HPLC) analysis were performed right after DevS purification process. The results of LALS for BSA proved to be highly reliable with a Rh value of c.a. 3.7 nm. Considering BSA a globular protein, the molecular weight estimative, using LALS was near 67 KDa, which is reasonably within the value reported in the literature. Preliminary LALS results showed a hydrodynamic radius (Rh) varying from 4.2-15.0 nm for DevS protein, and an average of 6.7 nm. These data supported, along with gel filtration, a dimer (~130 KDa) and tetramer (255 KDa) as the main DevS species. Additionally, it was found higher oligomeric species by gel filtration suggesting either an equilibrium of oligomers or an aggregation process that deserves further studies.

  19. L’essor et le déclin de la stratégie économique keynésienne – structuraliste au Mexique Rise and demise of the Structuralist-Keynesian economic strategy in Mexico La expansión y la declinación de la estrategia económica keynesiana-estructuralista en México

    OpenAIRE

    Julio López G.

    2012-01-01

    Pendant au moins deux décennies après la seconde guerre mondiale, la croissance économique au Mexique a été très rapide, à tel point que pour la caractériser, le terme « miracle mexicain » a été introduit. Le but de ce travail est d’étudier les causes immédiates ainsi que les origines historiques de l’essoufflement du miracle mexicain. L’auteur examine les limites de la stratégie fondée sur la substitution des importations en prenant en compte aussi bien des problèmes du côté de l’offre que d...

  20. 气相氯交换的SN2(C)、SN2(N)、SN2(Si)和SN2(P)反应的理论研究%Theoretical study on SN2 (C) , SN2 (N), SN2 (Si) and SN2 (P) reactions with Cl-in the gas phase

    Institute of Scientific and Technical Information of China (English)

    丁艳丽

    2013-01-01

    利用从头算方法研究了以C、N、Si和P为反应中心恒等的Cl交换SN2反应.研究表明,所讨论的八个反应,无论是背面还是前面进攻的反应活化能都受到中心原子极化率和电负性的影响:中心原子的极化率越大,反应需要的活化能越低,反应越容易进行;中心原子的电负性越大,反应需要的活化能越高,反应越不容易进行.

  1. 安神一号胶囊与劳拉西泮治疗躯体形式障碍自主神经紊乱的疗效比较%Clin ical Study on Treaing P atien ts with S om atoform Disorder and Auton om ic Nervous Disorder with AnShenYiHao Capsule or L orazepam

    Institute of Scientific and Technical Information of China (English)

    石洲宝; 刘敏科; 申希平; 黄生辉; 陈林庆; 赵剑华

    2011-01-01

    目的:比较安神一号胶囊与劳拉西泮治疗躯体形式障碍自主神经紊乱的疗效.方法:将90例躯体形式障碍自主神经紊乱住院患者随机分为2组,安神一号胶囊组与劳拉西泮组各45例,治疗8周,采用Hamilton Anxiety Scale(HAMA)和Clinical Global ImpresGIon-global improvement(CGI-GI)评定临床疗效.结果:安神一号胶囊与劳拉西泮有效率分别为:86.66%和82.22%,2组疗效差异无统计学意义(P>0.05).结论:安神一号胶囊与劳拉西泮治疗躯体形式障碍自主神经紊乱疗效相当.%Objective:To compare the efficacy of treating patients with somatoform disorder and autonomic nervous disorder with A nShen YiHao capsule or lorazepam. Method:90 cases of patients with somatoform disorder and autonomic nervous disorder were randomly divided into two groups, each group had 45 cases and treated for 8 weeks,one group were treated with lorazepam and another gronp were treated with AnShen YiHao capsule,assessed the clinical efficacy using(Hamilton Anxiety Scale,HAMA) and(Clinical Global InpresGIon-global improvement, CGI-GI).Result:The total effective rates of the AnShen YiHao capsule group and the lorazepam group were 86.66% and 82.22% after 8 weeks of treannent,the differences in efficacy between two groups had no significant difference (P>0.05).Conclusion:AnShen YiHao capsnle and lorazepam have considerable effect on treating patients with somatoform disorder and atntonomic nervous disorder.

  2. A mapping study on cooperation between information system development and operations

    NARCIS (Netherlands)

    Erich, Floris; Amrit, Chintan; Daneva, Maya; Jedlitschka, Andreas; Kuvaja, Pasi; Kuhrmann, Marco; Männistö, Tomi; Münch, Jürgen; Raatikainen, Mikko

    2014-01-01

    DevOps is a conceptual framework for reintegrating development and operations of Information Systems.We performed a Systematic Mapping Study to explore DevOps. 26 articles out of 139 were selected, studied and summarized. Based on this a concept table was constructed. We discovered that DevOps has n

  3. West Syndrome in South Iran: Electro-Clinical Manifestations

    Directory of Open Access Journals (Sweden)

    ALI Akabar ASADI-POOYA

    2013-08-01

    . Infantile spasms: West syndrome. Arch Neurol. 2002 Feb;59(2:317-8.3. Hrachovy RA. West’s syndrome (infantile spasms.Clinical description and diagnosis. Adv Exp Med Biol.2002;497:33-50. Review.4. Riikonen R, Donner M. Incidence and aetiology of infantile spasms from 1960 to 1976: a population study in Finland. Dev Med Child Neurol. 1979 Jun;21(3:333-43.5. Dulac O. What is West syndrome? Brain Dev. 2001 Nov;23(7:447-52. Review. 6. Wong V. West syndrome-The University of Hong Kong experience (1970-2000. Brain Dev. 2001 Nov;23(7:609-15.7. Kalra V, Gulati S, Pandey RM, Menon S. West syndrome and other infantile epileptic encephalopathies -Indian hospital experience. Brain Dev. 2001 Nov; 23(7:593-602. Corrected and republished in: Brain Dev. 2002 Mar;24(2:130-9.8. Young C; Taiwan Child Neurology Society. National survey of West syndrome in Taiwan. Brain Dev. 2001 Nov;23(7:570-4.9. Asadi-Pooya AA, Mintzer S, Sperling MR. Nutritional supplements, foods, and epilepsy: is there a relationship?Epilepsia. 2008 Nov;49(11:1819-27.10. Mikati MA, Trevathan E, Krishnamoorthy KS, Lombroso CT. Pyridoxine - dependent epilepsy: EEG investigations and long-term follow-up. Electroencephalogr Clin Neurophysiol. 1991 Mar;78(3:215-21.11. Nabbout R, Soufflet C, Plouin P, Dulac O. Pyridoxine dependent epilepsy: a suggestive electroclinical pattern. Arch Dis Child Fetal Neonatal Ed. 1999 Sep;81(2:F125-9.12. Gospe SM Jr. Pyridoxine-dependent seizures: new genetic and biochemical clues to help with diagnosis and treatment. Curr Opin Neurol. 2006 Apr;19(2:148-53. Review.13.Riikonen R. The latest on infantile spasms. Curr Opin Neurol. 2005 Apr;18(2:91-5. Review.

  4. 无动力蝶式止回阀关阀起动转矩自动瞬间加载装置设计%Design of Shut Down Starting Moment of Torsion Auto-momentary Dev ice for Non-power Butterfly Check Valve

    Institute of Scientific and Technical Information of China (English)

    俞劬严

    2001-01-01

    阐述了无动力止回阀设置关阀起动加载装置的必要性,介绍了一种利用给排水系统运行及正常停泵或事故停泵时瞬间介质压差对止回阀起动转矩进行自动、瞬间加载的装置,及其主要结构元件的设计。%The necessity of valve shut down starting loading device fornon-power check valve are described and a kind of valve are intrduced which have a auto-momentaryl oading device of starting moment of torsion acted by momentary deferential press ure by drainage pipeline system at normal stop sorking or breakdown condition.

  5. The Association of Pre-storm Ground Wetness with Inland Penetration of Monsoon Depressions : A Study Using Self Organizing Maps (SOM) C.M. Kishtawal Meteorology and Oceanography Group, Space Applications Center, Ahmedabad, INDIA Dev Niyogi2 Department of Agronomy, and Department of Earth and Atmospheric Sciences, Purdue University, West Lafayette, Indiana

    Science.gov (United States)

    Kishtawal, C. M.; Niyogi, D.

    2009-12-01

    Monsoon depressions (MDs)are probably the most important rain bearing systems that occur during the Indian summer monsoon season. The unique topography of Indian peninsula and Indo-china region favor the formation and development of MDs in the warm and moist air over the Bay of Bengal. After formation the MDs move in a north-northwest track along the monsoon trough to the warmer and drier heat low regions of Northwest India and Pakistan. The dynamic structure of MDs is largely maintained by convergence of atmospheric water vapor flux coupled with the lower tropospheric divergent circulation (Chen et al., 2005), and they weaken rapidly after landfall due to the lack of surface moisture fluxes (Dastoor and Krishnamurti, 1991). In the present study we explored the association between pre-storm wetness conditions and the post-landfall situation of MDs using 54-year long observations (1951-2004) of 183 MDs and daily surface rainfall. Our analysis suggests that the MD’s post-landfall behavior is most sensitive to mean inland rainfall between To-1 to To-8 days (the pre-storm rainfall), where To is the day of formation of MD in the Bay of Bengal. Further, pre-storm rainfall over a broad region along the monsoon trough is found to exhibit the maximum association with the MDs inland lifespan. We further carried out the unsupervised classification of pre-storm rainfall patterns using Self Organizing Map(SOM), a topology preserving map that maps data from higher dimensions onto a two dimensional grid(Kohenen, 1990). The SOM patterns of rainfall indicate that pre-storm wetness is strongly associated with the inland penetration length of MDs with wetter conditions supporting MDs to survive longer after the landfall. Although the pre-storm inland wetness has not been found to be associated with the formation of MDs and a number of MDs form during relatively dry inland conditions during the early (June) and late (September) phases of monsoon, the inland-penetration and post-landfall lifespan of these MDs was found significantly smaller compared to those formed under wetter inland conditions. Interestingly, the formation of a considerably larger number of MDs was associated with axially concentrated (around monsoon trough) patterns of pre-storm rainfall than the wide-spread patterns. The inland rainfall patterns are possibly the manifestation of the strength and orientation of Tropical Convergence Zone (TCZ) that also supports the genesis of MDs through the enhancement of barotropic instability. References Chen T.C., J.H. Yoon, and S.Y. Wang, 2005 : Westward propagation of the Indian monsoon depression. Tellus, 57A, 758-769. Dastoor A., and T.N. Krishnamurti, 1991: The landfall and structure of a tropical cyclone : The sensitivity of model predictions to soil moisture parameterizations. Boundary Layer Meteorol., 55, 345-380. Kohenen, T., 1990 : The self organizing map. Proc IEEE .78(9):1464-1480.

  6. Neuroimaging in Cerebral Palsy – Report from North India

    Directory of Open Access Journals (Sweden)

    Anju AGGARWAL

    2013-11-01

    ;109:8-14.http://www.newbornwhocc.org/pdf/database.pdfRikomen R, Raumanvrita S, Sinivuori E, Seppala T. Changing pattern of cerebral palsy in southwest region of Finland. Acta Pediatr Scand 1989; 78(4:581-7.Pharaoh POD, Plat MJ, Cooke T. The changing epidemiology of cerebral palsy. Arch Dis Child 1996;75(3: F169-73.Eischer PS, Batshaw M. Cerebral Palsy. Ped Clin North Am 1993;40(3:537-51.Bax M, Tydeman BA, Flodmark O. Clininical and MRI correlates of cerebral palsy: the European Cerebral PalsyStudy. JAMA 2006; 296(13:1602-08.Korzeniewski SJ, Birbeck G, DeLano MC, Potchen MJ, Paneth N. A systematic review of neuroimaging for cerebral palsy. Journal of Child Neurology 2008;23(2:216-27.Robinson MN, Peake LJ, Ditchfield MR, Reid SM. Magnetic Resonance imaging findings in population based cohort of children with cerebral palsy Dev Med Child Neurol 2009; 51(1:39-45.Shevell M, Ashwal S, Donley D, Flint J, Gingold M, Hirtz D, et al. Practice parameter: Evaluation of the child with global developmental delay: Report of the Quality Standards Subcommittee of the American Academy of Neurology and The Practice Committee of the Child Neurology Society. Neurology 2003; 60(3; 367-80.Ashwal S, Russman BS, Blasco PA, Miller G, Sandler A, Shevell M, et al. Practice parameter: diagnostic assessment of the child with cerebralpalsy: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology 2004; 23;62(6: 851-63. 

  7. Associations between Manual Abilities, Gross Motor Function, Epilepsy, and Mental Capacity in Children with Cerebral Palsy

    Directory of Open Access Journals (Sweden)

    Ewa GAJEWSKA*

    2014-04-01

    2013;111:183-95.Sellier E, Uldall P, Calado E, Sigurdardottir S, Torrioli MG, Platt MJ, et al. Epilepsy and cerebral palsy: characteristics and trends in children born in 1976-1998. Eur J Paediatr Neurol 2012;16(1:48-55.Wallace SJ. Epilepsy in cerebral palsy. Dev Med Child Neurology 2001;43(10:713-7.Bax MCO. Cerebral palsy. In: Aicardi J, editor. Disease of the nervous system in childhood. 2nd ed. London: Mc Keith Press; 1998. p. 210-39.Reid A, Imrie H, Brouwer E, Clutton S, Evans J, Russell D, et al. “If I knew then what I know now”: parents’ reflections on raising a child with cerebral palsy. Phys Occup Ther Pediatr 2011;31(2:169-83.Rosenbaum P, Paneth N, Leviton A, Goldstein M, Bax M, Damiano D, et al. A report: the definition and classification of cerebral palsy April 2006. Dev Med Child Neurology 2007;109:8-14.Palisano R, Rosenbaum P, Bartlett D, Livingston M. Content validity of the expanded and revised Gross Motor Function Classification System. Dev Med Child Neurology 2008;50(10:744-50.Öhrvall AM, Eliasson AC. Parents and therapists perceptions about the content and construct of Manual Ability Classification System, MACS. Scand J Occup Ther 2010;17(3:209-16.Marszał E.Występowanie, diagnostyka i leczenie padaczki u dzieci z mózgowym porażeniem dziecięcym. Neurologia dziecięca;2006:15, 30:65-8.Blair E, Watson L. Epidemiology of cerebral palsy. Semin Fetal Neonatal Medicine 2006;11(2:117-25.Meberg A, Broch H. Etiology of cerebral palsy. J Perinat Med 2004;32(5:434-9.Blair E. Epidemiology of the cerebral palsies. Orthop Clin North Am 2010;41(4:441-55.Hellbrűge T, Fritz L, Menara D, Schamberger R, Rautenstrauch T. Monachijska Funkcjonalna Diagnostyka Rozwojowa. Kraków: Antykwa; 1994. p. 80-130.Arnould C, Penta M, Renders A, Thonnard JL. Abilhand-Kids: a measure of manual ability in children with cerebral palsy. Neurology 2004;63(6:1045-52.Carnahan KD, Arner M, Hägglund G. Association between gross motor function (GMFCS and manual ability (MACS in

  8. Disease: H01245 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available munodeficiency yet without anhidrotic ectodermal dysplasia. J Allergy Clin Immunol 114:1456-62 (2004) PMID:1...ult in immunodeficiency without ectodermal dysplasia. J Allergy Clin Immunol 114:650-6 (2004) ...

  9. Disease: H00085 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available une deficiencies. Immunol Allergy Clin North Am 28:387-412, x (2008) PMID:17952897 (gene) Geha RS, Notarange...cal Societies Primary Immunodeficiency Diseases Classification Committee. J Allergy Clin Immunol 120:776-94 (2007) ...

  10. An Analysis of Army Hazardous Waste Disposal Cost Data

    Science.gov (United States)

    1991-04-01

    Acid Cl 1331 Ammonium Acid Flouride (aimonium - - biflouride) 1332 Acetic lb 1333 Blattery Electrolyte ( sulfuric acid ) lb - . . . 1334 Chromic...1341 Sulfuric lb 1342 Sodium Bisulfite (sodium acid sulfite) lb 1343 Sodium Bisulfate (sodium acid sulfate) lb 1344 Hydrofluosilicic Acid lb 1345...battery category CLINs (0500 - 0599) with CLIN 1333 for battery electrolyte ( sulfuric acid ), CLIN 1309 battery electrolyte ( sulfuric acid

  11. 3CE Methodology for Conducting a Modeling, Simulation, and Instrumentation Tool Capability Analysis

    Science.gov (United States)

    2010-05-01

    System Design System Dev DT&E IOT &E Operations 3CE – Core Products Process & Procedures Data Toolbox 3CE Network TRADOC RDECOMATEC 3CE...JCS COCOM FCB Strategic Guidance Materiel Solution Analysis ICD MDD Technology Opportunities & Resources AOA LiveVirtual Constructive Concept Dev ... DEV , DTE, SIMEX, LUT, L-V-C, etc… • Research Requirements •Test Requirements •Training Requirements • PM Requirements Source of Requirements

  12. Joint Standoff Weapon - Baseline Variant and Unitary Warhead Variant (JSOW)

    Science.gov (United States)

    2013-12-01

    Validation DEV - Development DT - Developmental Test DT&E - Developmental Test and Evaluation E&MD - Engineering and Manufacturing Development IOT ...Information Retrieval Dev Est - Development Estimate DoD - Department of Defense DSN - Defense Switched Network Econ - Economic Eng - Engineering Est...Milestone II E&MD Contract Award BLU-108 SYSTEM Milestone II Pre-E&MD Contract Award Preliminary Fit Checks Eng Dev Test Vehicle Deli... F-16

  13. Applications of Should Cost to Achieve Cost Reductions

    Science.gov (United States)

    2014-04-01

    Defense Acquisition University DDG . . . . . . . . . Guided Missile Destroyer Demo . . . . . . . . . . . . . . . . . Demonstration Dev ...Integrated Fire Control Network IMU . . . . . . . . . . Inertial Measurment Unit IOC . . . . . . .Initial Operational Capability IOT . . . . . . . . . Initial

  14. Interactive Vulnerability Analysis Enhancement Results

    Science.gov (United States)

    2012-12-01

    Now, DevOps is reducing those times to days, or even a matter of hours. The traditional assurance approaches simply can’t operate in these...development methodologies, such as Agile and DevOps . With releases occurring monthly, weekly, daily, or even many times an hour, traditional security

  15. Strategy for increasing marine fish production in Goa

    Digital Repository Service at National Institute of Oceanography (India)

    Parulekar, A.H.

    stream_size 5 stream_content_type text/plain stream_name Proc_Workshop_Evol_Strat_Dev_Agric_Anim_Husb_Fish_Goa_1991_73.pdf.txt stream_source_info Proc_Workshop_Evol_Strat_Dev_Agric_Anim_Husb_Fish_Goa_1991_73.pdf.txt Content...

  16. The vaccine efficacy of recombinant duck enteritis virus expressing secreted E with or without PrM proteins of duck tembusu virus.

    Science.gov (United States)

    Chen, Pucheng; Liu, Jinxiong; Jiang, Yongping; Zhao, Yuhui; Li, Qimeng; Wu, Li; He, Xijun; Chen, Hualan

    2014-09-15

    A newly emerged tembusu virus that causes egg-drop has been affecting ducks in China since 2010. Currently, no vaccine is available for this disease. A live attenuated duck enteritis virus (DEV; a herpesvirus) vaccine has been used routinely to control lethal DEV in ducks since the 1960s. Here, we constructed two recombinant DEVs by transfecting overlapping fosmid DNAs. One virus, rDEV-TE, expresses the truncated form of the envelope glycoprotein (TE) of duck tembusu virus (DTMUV), and the other virus, rDEV-PrM/TE, expresses both the TE and pre-membrane proteins (PrM). Animal study demonstrated that both recombinant viruses induced measurable anti-DTMUV neutralizing antibodies in ducks. After two doses of recombinant virus, rDEV-PrM/TE completely protected ducks from DTMUV challenge, whereas rDEV-TE only conferred partial protection. These results demonstrate that recombinant DEV expressing the TE and pre-membrane proteins is protective and can serve as a potential candidate vaccine to prevent DTMUV infection in ducks.

  17. Brief Report: Insistence on Sameness, Anxiety, and Social Motivation in Children with Autism Spectrum Disorder

    Science.gov (United States)

    Factor, Reina S.; Condy, Emma E.; Farley, Julee P.; Scarpa, Angela

    2016-01-01

    While the function of restricted repetitive behaviors (RRBs) in autism spectrum disorder (ASD) is unclear, RRBs may function as anxiety reduction strategies (Joosten et al. "J Autism Dev Disord" 39(3):521-531, 2009. Moreover, anxiety in ASD is associated with low social motivation (Swain et al. "J Autism Dev Disord," 2015. The…

  18. Surface Warfare Center Contributions for Addressing Warfare System Development Challenges and Goals

    Science.gov (United States)

    2011-04-30

    during IOT &E"." "there was a loss of a large number of the most experienced management and technical personnel ...without an adequate replacement...Project Management IPT Lead Government Leadership and Development Oversight: Technical Direction Activity Dev Team Management IPT Dev Org’s Project

  19. NCBI nr-aa BLAST: CBRC-PABE-24-0031 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-PABE-24-0031 ref|YP_001276205.1| CRISPR-associated autoregulator, DevR family ...[Roseiflexus sp. RS-1] gb|ABQ90255.1| CRISPR-associated autoregulator, DevR family [Roseiflexus sp. RS-1] YP_001276205.1 5.9 32% ...

  20. Epo and non-hematopoietic cells: what do we know?

    Science.gov (United States)

    Ogunshola, Omolara O; Bogdanova, Anna Yu

    2013-01-01

    The hematopoietic growth factor erythropoietin (Epo) circulates in plasma and controls the oxygen carrying capacity of the blood (Fisher. Exp Biol Med (Maywood) 228:1-14, 2003). Epo is produced primarily in the adult kidney and fetal liver and was originally believed to play a role restricted to stimulation of early erythroid precursor proliferation, inhibition of apoptosis, and differentiation of the erythroid lineage. Early studies showed that mice with targeted deletion of Epo or the Epo receptor (EpoR) show impaired erythropoiesis, lack mature erythrocytes, and die in utero around embryonic day 13.5 (Wu et al. Cell 83:59-67, 1995; Lin et al. Genes Dev. 10:154-164, 1996). These animals also exhibited heart defects, abnormal vascular development as well as increased apoptosis in the brain suggesting additional functions for Epo signaling in normal development of the central nervous system and heart. Now, in addition to its well-known role in erythropoiesis, a diverse array of cells have been identified that produce Epo and/or express the Epo-R including endothelial cells, smooth muscle cells, and cells of the central nervous system (Masuda et al. J Biol Chem. 269:19488-19493, 1994; Marti et al. Eur J Neurosci. 8:666-676, 1996; Bernaudin et al. J Cereb Blood Flow Metab. 19:643-651, 1999; Li et al. Neurochem Res. 32:2132-2141, 2007). Endogenously produced Epo and/or expression of the EpoR gives rise to autocrine and paracrine signaling in different organs particularly during hypoxia, toxicity, and injury conditions. Epo has been shown to regulate a variety of cell functions such as calcium flux (Korbel et al. J Comp Physiol B. 174:121-128, 2004) neurotransmitter synthesis and cell survival (Velly et al. Pharmacol Ther. 128:445-459, 2010; Vogel et al. Blood. 102:2278-2284, 2003). Furthermore Epo has neurotrophic effects (Grimm et al. Nat Med. 8:718-724, 2002; Junk et al. Proc Natl Acad Sci U S A. 99:10659-10664, 2002), can induce an angiogenic phenotype in cultured

  1. Effect of Transforming Growth Factor-

    Institute of Scientific and Technical Information of China (English)

    CAO; Yang(

    2001-01-01

    [1]Alvarado J Murphy C Juster R et al.Trabecular meshwork cellularity in primary open angle glaucoma and nonglaucomatous normals.Ophthalmology 1984 91:564[2]Grierson I Hogg P.The proliferative and migratory activitues of trabecular meshwork cells.Prog Retinal Eye Res 1995 15:33[3]Tripathi R C Li J Chan W F et al.Aqueous humor in glaucomatous eyes contains an increased level of TGF-β2.Exp Eye Res 1994 59:723[4]Wang Q Wei H Fan Z et al.Effect of norfloxacin and clonidine on human trabecular meshwork cells in vitro.Graefe's Arch Clin Exp Ophthalmol 1994 232:566[5]Sherwood M E Richardson T M.Phagocytosis by trabecular meshwork cells:sequence of events in cats and monkeys.Exp Eye Res 1988 46:881[6]Zhou L Fukuchi T Kawa J et al.Loss of cell-matrix cohesiveness after phagocytosis by trabecular meshwork cells.Invest Ophthalmol Vis Sci 1995 36:787[7]Zhou L Li Y Yue B Y.Alteration of phagocytosis chal&127;lenge in cells from an ocular tissue-the trabecular meshwork.In Vitro Cell Dev Biol Anim 1999 35:144[8]曹阳 魏厚仁 富名水等.体外培养牛眼小梁细胞表达转化生长因子β及其蛋白.眼科研究 2000 18:235[9]Li J Tripathi R C Tripathi B J.Modulation of pre-mRNA splicing and protein production of fibronectin by TGF-beta2 in porcine trabecular cells.Invest Ophthalmol Vis Sci 2000 41:3437[10]钟丽春 李美玉.转化生长因子-β1对培养的人眼小梁细胞微丝肌动蛋白的影响.中华眼科杂志 1999 35:186

  2. Characterization of nucleocytoplasmic shuttling and intracellular localization signals in Duck Enteritis Virus UL54.

    Science.gov (United States)

    Liu, Chaoyue; Cheng, Anchun; Wang, Mingshu; Chen, Shun; Jia, Renyong; Zhu, Dekang; Liu, Mafeng; Sun, Kunfeng; Yang, Qiao; Chen, Xiaoyue

    2016-08-01

    Duck Enteritis virus (DEV) UL54 is a homolog of herpes simplex virus-1 (HSV-1) trafficking protein ICP27, which plays an essential role in infection. In this study, DEV UL54 shuttling between the nucleus and cytoplasm was verified with a heterokaryon assay. One predicted nuclear export sequence (NES) (339-348 aa) was shown to be functional and chromosomal region maintenance 1 (CRM1)-dependent; however, the insensitivity of UL54 to Leptomycin B (LMB) and NES mutation suggests that other mechanisms are responsible for the observed nuclear export. Next, three non-classical nuclear localization sequences (NLSs), referred to as NLS1 (105-122 aa), NLS2 (169-192 aa) and NLS3 (257-274 aa), were identified. Furthermore, a recombinant DEV with the UL54 NLSs deleted (DEV- UL54 mNLSs) was constructed and showed that UL54 NLSs moderately affected DEV growth.

  3. Advanced System for Worldwide Surveillance of Rickettsial Disease Antibodies. Phase 1

    Science.gov (United States)

    1996-10-01

    terization of ehrlichia : protein immunoblotting of Ehrlichia canis , Ehrlichia sennetsu, and Ehrlichia risticii. J. Clin. Microbiol. 30:1062-1066. 11. Chen...Perez, M., Y. Rikihisa, and B. Wen. 1996. Ehrlichia canis -like agent isolated from a man in Venezuela: antigenic and genetic characterization. J. Clin...1994. Western immunoblot analysis of Ehrlichia chaffeensis, E. canis , or E. ewingii infections in dogs and humans. J. Clin. Microbiol. 32:2107-2112

  4. The Best Time for EEG Recording in Febrile Seizure

    Directory of Open Access Journals (Sweden)

    Parvaneh KARIMZADEH

    2014-01-01

    seizures. Arch Pediatr Adolesc Med 1997;151(4:371-8.Nelson KB, Ellenberg JH. Predictors of epilepsy in children who have experienced febrile seizures. N Engl J Med 1976;295(19:1029-33.Anonymous. Practice parameter: the neurodiagnostic evaluation of the child with a first simple febrile seizure. American Academy of Pediatrics. Provisional Committee on Quality Improvement, Subcommittee on Febrile Seizures. Pediatrics 1996;97(5:769-72; discussion:773-5.Rosman NP. Evaluation of the child who convulses with fever. Paediatr Drugs 2003;5(7:457-61.Kanemura H, Mizorogi S, Aoyagi K, Sugita K, Aihara M. EEG characteristics predict subsequent epilepsy in children with febrile seizure. Brain Dev 2012;34(4:302-7.Yamatogi Y, Ohtahara S. EEG in febrile convulsions. Am J EEG Techno1 1990;30:267-80.Aicardi J, Chevrie JJ. The significance of electroencephalographic paroxysms in children less than 3 years of age. Epilepsia 1973;14(1:47-55.Tsuboi T. Seizures of childhood: a population-based and clinic based study. Acta Neurol Scand Suppl 1986;110:1-237.Maytal J, Steele R, Eviatar L, Novak G. The value of early postictal EEG in children with complex febrile seizures. Epilepsia 2000;41(2:219-21.Joshi C, Wawrykow T, Patrick J, Prasad A. Do clinical variables predict an abnormal EEG in patients with complex febrile seizures? Seizure 2005;14(6:429-34.Lennox-Buchthal M. Febrile convulsions: a reappraisal. Electroencephalogr Clin Neurophysiol 1973;32:Suppl:1-138.Frantzen E, Lennox-Buchtal MA, Nygraad A. Longitudinal EEG and clinical study of children with febrile convulsions. Electroencephalogr Clin Neurophysiol 1968;24(3:197-212.Kajitani T, Ueoka K, Nakamura M, Kumanomidou Y. Febrile convulsions and rolandic discharges. Brain Dev 1981;3(4:351-9.Sofijanov N, Emoto S, Kuturec M, Dukovski M, Duma F, Ellenberg JH, et al. Febrile seizures: clinical characteristics and initial EEG. Epilepsia 1992;33(1:52-7.

  5. Protective effects of recombinant glycoprotein D based prime boost approach against duck enteritis virus in mice model.

    Science.gov (United States)

    Aravind, S; Kamble, Nitin Machindra; Gaikwad, Satish S; Shukla, Sanjeev Kumar; Saravanan, R; Dey, Sohini; Mohan, C Madhan

    2015-11-01

    Duck virus enteritis, also known as duck plague, is an acute herpes viral infection of ducks caused by duck enteritis virus (DEV). The method of repeated immunization with a live attenuated vaccine has been used for the prevention and control of duck enteritis virus (DEV). However, the incidence of the disease in vaccinated flocks and latency reactivation are the major constraints in the present vaccination programme. The immunogenicity and protective efficacy afforded by intramuscular inoculation of plasmid DNA encoding DEV glycoprotein D (pCDNA-gD) followed by DEV gD expressed in Saccharomyces cerevisia (rgD) was assessed in a murine model. Compared with mice inoculated with DNA (pCDNA-gD) or protein (rgD) only, mice inoculated with the combination of gD DNA and protein had enhanced ELISA antibody titers to DEV and had accelerated clearance of virus following challenge infection. Furthermore, the highest levels of lymphocyte proliferation response, IL-4, IL-12 and IFN-γ production were induced following priming with the DNA vaccine and boosting with the rgD protein. For instance, the specially designed recombinant DEV vector vaccine would be the best choice to use in ducks. It offers an excellent solution to the low vaccination coverage rate in ducks. We expect that the application of this novel vaccine in the near future will greatly decrease the virus load in the environment and reduce outbreaks of DEV in ducks.

  6. Disease: H00101 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee. J Allergy Clin Immunol 120:776-94 (2007) ...

  7. The Classification of Multi-Edge Shapes Using An Autoregressive Model and the Karhunen-Loeve Expansion,

    Science.gov (United States)

    1985-12-01

    SUMI,SUM2 REAL ALPHA,BETA, ALBET REAL RAD(-2:2t0,O),THETA(11,10),RX(0:10,10) REAL ALL(10,11,10) REAL RXN(O:O,10O) REAL SIGMAS(10),A(1O,10) COMMON DEV,IN...BETA = SIGMAS(M) ALBET = ALPHA /SGRT(BETA) THETA(M+1,N) = ALBET C WRITE(DEV,425) (I, (A(K,,I) ,K1,M) ,I=1,M) C 425 FORMAT(1X,I3,3X,M:.F.3) C WRITE(DEV

  8. 76 FR 28435 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

    Science.gov (United States)

    2011-05-17

    ... Street, Dallas, Texas 75201-2272: 1. Viewpoint Financial Group, Inc., Plano, Texas; to become a bank..., Plano, Texas. Board of Governors of the Federal Reserve System, May 12, 2011. Robert deV....

  9. National Weather Service: Watch, Warning, Advisory Display

    Science.gov (United States)

    weather.gov Site Map News Organization Search for: SPC NCEP All NOAA Search by city or zip ... Fire Wx Outlooks RSS Feeds E-Mail Alerts Weather Information Storm Reports Storm Reports Dev. NWS Hazards ...

  10. Annular Hybrid Rocket Motor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Engineers at SpaceDev have conducted a preliminary design and analysis of a proprietary annular design concept for a hybrid motor. A U.S. Patent application has been...

  11. Vee hinna uuring läheb maksma 200 000 kroonii / Tuuli Aug

    Index Scriptorium Estoniae

    Aug, Tuuli

    2010-01-01

    Tallinna linnavalitsus tellis Briti konsultatsioonifirmalt vee hinna määramise uuringu, mis analüüsiks, kas konkurentsiameti hinnauuring oli pädev. Tallinnal tuleb vee hind edaspidi kooskõlastada konkurentsiametiga

  12. Disease: H00606 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Ohtahara syndrome; its overview referring to our 16 cases. Brain Dev 24:13-23 (2002) PMID:18469812 Saitsu H,... Y, Ohtahara S Early-infantile epileptic encephalopathy with suppression-bursts,

  13. Lipotoxicity and the role of maternal nutrition

    NARCIS (Netherlands)

    Pruis, M. G. M.; van Ewijk, P. A.; Schrauwen-Hinderling, V. B.; Ploesch, T.

    2014-01-01

    Intrauterine malnutrition predisposes the offspring towards the development of type 2 diabetes and cardiovascular disease. To explain this association, the Developmental Origins of Health and Disease hypothesis was introduced, meaning that subtle environmental changes during embryonic and foetal dev

  14. Hyperspectral remote sensing of tropical grass quality and quantity

    NARCIS (Netherlands)

    Mutanga, O.

    2004-01-01

    Resource distribution is a fundamental factor governing the movement and distribution of herbivores. Specifically, the quality (foliar concentration of nitrogen, phosphorous, calcium, magnesium, potassium and sodium) and quantity (biomass) of vegetation are important factors. In this regard, the dev

  15. Genomic regulatory landscapes and chromosomal rearrangements

    DEFF Research Database (Denmark)

    Ladegaard, Elisabete L Engenheiro

    2008-01-01

    The main objectives of the PhD study are to identify and characterise chromosomal rearrangements within evolutionarily conserved regulatory landscapes around genes involved in the regulation of transcription and/or development (trans-dev genes). A frequent feature of trans-dev genes...... the complex spatio-temporal expression of the associated trans-dev gene. Rare chromosomal breakpoints that disrupt the integrity of these regulatory landscapes may be used as a tool, not only to make genotype-phenotype associations, but also to link the associated phenotype with the position and tissue...... specificity of the individual CNEs. In this PhD study I have studied several chromosomal rearrangements with breakpoints in the vicinity of trans-dev genes. This included chromosomal rearrangements compatible with known phenotype-genotype associations (Rieger syndrome-PITX2, Mowat-Wilson syndrome-ZEB2...

  16. Bioinformatics Analysis of the Duck Enteritis Virus UL54 Gene

    Directory of Open Access Journals (Sweden)

    Chaoyue Liu

    2014-04-01

    Full Text Available In this study, we analyze the Duck Enteritis Virus (DEV UL54 gene, which has been isolated and identified in our lab (GenBank accession NO EU071033, to help deeply research on DEV. DNA sequence analysis showed that the identified ORF which composed of 1377 bp nucleotides encoded 458 amino acids with a predicted Mr. of 51.75 kDa. Multiple sequence alignment suggested that the UL54 gene was highly conserved in Alphaherpesvirinae and was similar to the other herpesviral UL54 gene. Phylogenetic analysis of the DEV UL54 gene revealed that DEV had a close evolutionary relationship with Gallid, Herpesvirus 2 (GaHV-2, Gallid Herpesvirus 3 (GaHV-3, Meleagrid Herpesvirus1 (MeHV-1 and should belong to a single cluster within the Alphaherpesvirinae subfamily.

  17. Experiment list: SRX1206064 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DMEM 10% FCS,+ hygromycin + blasticidin + doxycycline + a-amanitin || antibody=rabbit anti pan CTD (Schroe...der eta l Genes Dev. 14:2435, 2000) http://dbarchive.biosciencedbc.jp/kyushu-u/hg19

  18. Value Chains, Social Inclusion and Economic Development : Contrasting Theories and Realities

    NARCIS (Netherlands)

    Helmsing, A.H.J.; Vellema, S.

    2011-01-01

    Lead firms, development organisations, donors and governments view value chains and voluntary standards as vital instruments for achieving millennium development goals through trade and market-related interventions. The precise foundations for these development strategies, which suggest positive dev

  19. Combined Effects of Primary and Tertiary Blast on Rat Brain: Characterization of a Model of Blast-induced Mild Traumatic Brain Injury

    Science.gov (United States)

    2013-03-01

    Basile AS, Huang JM, Xie C, Webster D, Berlin C, Skolnick P: N-methyl-D-aspartate antagonists limit aminoglycoside antibi- otic-induced hearing loss...specific biomarkers of tissue injury. Clin Chem 55: 1977–1983. clinchem.2009.131797 [pii];10.1373/clin- chem.2009.131797 [doi]. 25. Redell JB, Moore AN

  20. Disease: H00094 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available agnosis of primary immune deficiencies. Immunol Allergy Clin North Am 28:387-412, x (2008) PMID:17952897 (ge...update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee. J Allergy Clin Immunol 120:776-94 (2007) ...

  1. Disease: H01021 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available rs D Invasive infection with Rhodococcus equi--two case reports and review of literature. Acta Clin Belg 65:...ctor, drug) Vestbo J, Lundgren JD, Gaub J, Roder B, Gutschik E Severe Rhodococcus equi pneumonia: case report and literature review. Eur J Clin Microbiol Infect Dis 10:762-8 (1991) ...

  2. The Influence of Thermal Exposure on Diver Susceptibility to Decompression Sickness

    Science.gov (United States)

    2007-11-01

    Zweig , and A. C. Van Steirteghem, "Evaluating the Clinical Efficacy of Laboratory Tests," Am. J. Clin. Pathol., Vol. 79 (1983), pp. 78-86. 25. M. H... Zweig and G. Campbell, "Receiver-Operator Characteristic (ROC) Plots: A Fundamental Evaluation Tool in Clinical Medicine," Clin Chem., Vol. 39, No. 4

  3. A Randomized Controlled Trial of Online versus Clinic-Based CBT for Adolescent Anxiety

    Science.gov (United States)

    Spence, Susan H.; Donovan, Caroline L.; March, Sonja; Gamble, Amanda; Anderson, Renee E.; Prosser, Samantha; Kenardy, Justin

    2011-01-01

    Objective: The study examined the relative efficacy of online (NET) versus clinic (CLIN) delivery of cognitive behavior therapy (CBT) in the treatment of anxiety disorders in adolescents. Method: Participants included 115 clinically anxious adolescents aged 12 to 18 years and their parent(s). Adolescents were randomly assigned to NET, CLIN, or…

  4. Tulane/Xavier Vaccine Development/Engineering Project

    Science.gov (United States)

    2012-10-01

    M. Devanga Chinta, R. A. Graves, S. Pamujula, N. Praetorius, L. A. Bostanian, and T. K . Mandal. 2009. Spray dried chitosan as a direct compression...R. A. Graves, S. Pamujula, and T. K . Mandal. 2010. Controlled release multiple layer coatings . Drug Dev. Ind. Pharm. (Invited paper) Drug Dev. Ind...Dhule, S.; Penformis, P .; John, V.; Pochampally, R. "Curcumin-loaded Gamma Cyclodextrin Liposomal Nanoparticles as Delivery Vehicles for Osteosarcoma

  5. Characterization of codon usage bias in the dUTPase gene of duck enteritis virus

    Institute of Scientific and Technical Information of China (English)

    Lichan Zhao; Anchun Cheng; Mingshu Wang; Guiping Yuan; Mingsheng Cai

    2008-01-01

    A comparative analysis of the codon usage bias in the newly discovered dUTPase gene(Assigned Accession No.:DQ4861491 of the duck enteritis virus(DEV)and the dUTPase gene of 32 reference herpesviruses was performed.The results indicated that the DEV dUT-Pase gene encodes a protein of 477 amino acids,which includes five conserved motifs with a 3-1-2-4-5 arrangement.The codon adap-tation index(CAI),effective number of codons(ENC),and GC3s values indicated synonymous codon usage bias in the dUTPase gene of herpesviruses,and this synonymous bias was correlated with host evolution.The codon usage pattens of the DEV dUTPase gene were phylogenetically conserved and similar to that of the dUTPase genes of the avian alphaherpesvirus.Although codon usage in each micro-orgamsm was different,there were no strain-specific differences among them.Sixty-one codons in the predicted polypeptide.with a strong bias towards A and T at the third codon position,were used.Comparison of the codon usage in the dUTPase gene of different organisms revealed that there were 19 codons showing distinct codon usage differences between the DEV and Escherichia coli dUTPase genes;16 between the DEV and yeast dUTPase genes;and 15 between the DEV and human dUTPase genes.Analysis of variance(ANOVA) showed significant differences between the DEV and yeast dUTPase genes(r=0.536,P<0.01).The extent of codon usage bias in the DEV dUTPase gene was highly correlated with the gene expression level,therefore the results may provide usefu information for gene classification and functional studies.

  6. Altered Gastrointestinal Function in the Neuroligin-3 Mouse Model of Autism

    Science.gov (United States)

    2013-10-01

    Aggression in children and adolescents with ASD: prevalence and risk factors . J Autism Dev Disord 2011; 41(7): 926-937. 5. Betancur C, Sakurai T... obsessive compulsive disorder , and social anxiety disorder are most frequently observed. A significant proportion of patients with ASD also suffer...and Mazurek, M. O. (2011). Aggression in children and adolescents with ASD: prevalence and risk factors . J. Autism Dev. Disord . 41, 926–937. doi

  7. DMPD: Pathways connecting inflammation and cancer. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 18325755 Pathways connecting inflammation and cancer. Allavena P, Garlanda C, Borre...llo MG, Sica A, Mantovani A. Curr Opin Genet Dev. 2008 Feb;18(1):3-10. Epub 2008 Mar 5. (.png) (.svg) (.html) (.csml) Show Pathway...s connecting inflammation and cancer. PubmedID 18325755 Title Pathways connecting infl...ni A. Publication Curr Opin Genet Dev. 2008 Feb;18(1):3-10. Epub 2008 Mar 5. Pathway - PNG File (.png) SVG F

  8. Ground/Air Task Oriented Radar (G/ATOR)

    Science.gov (United States)

    2013-12-01

    DAMIR - Defense Acquisition Management Information Retrieval Dev Est - Development Estimate DoD - Department of Defense DSN - Defense Switched Network...Review Milestone C IOT &E Operational Assessment Full Rate Production Deci... IOC G/ATOR Milestone 8 Milestone C Initial Operational Test...82171 3 𔃻 4 𔃻 5 𔃻 6 𔃻 7 I I I I I I I I I I I I • • - 𔃻 8 I • • • • Milestones SAR Baseline Dev Est Current APB Production

  9. EA-18G Growler Aircraft (EA-18G)

    Science.gov (United States)

    2013-12-01

    Budget Authority/Budget Activity BY - Base Year DAMIR - Defense Acquisition Management Information Retrieval Dev Est - Development Estimate DoD...APR 2007 OCT 2007 JUL 2007 Initial Operational Test and Evaluation ( IOT &E)(Start) SEP 2008 SEP 2008 MAR 2009 SEP 2008 Initial Operational Capability...Initial SAR Baseline to Current SAR Baseline (TY $M) Initial PAUC Dev Est Changes PAUC Prod Est Econ Qty Sch Eng Est Oth Spt Total 93.573 4.150

  10. Ship to Shore Connector Amphibious Craft (SSC)

    Science.gov (United States)

    2013-12-01

    Unit Cost BA - Budget Authority/Budget Activity BY - Base Year DAMIR - Defense Acquisition Management Information Retrieval Dev Est - Development...2013 SAR April 16, 2014 17:40:03 UNCLASSIFIED 7 Schedule Milestones SAR Baseline Dev Est Current APB Development Objective...2017 AUG 2017 FEB 2017 Craft 101 Delivery AUG 2017 AUG 2017 FEB 2018 AUG 2017 OPEVAL/ IOT &E APR 2018 APR 2018 OCT 2018 APR 2018 FRP Decision SEP 2018

  11. Emerging Global Trends in Advanced Manufacturing

    Science.gov (United States)

    2012-03-01

    SEMATECH) Celia Merzbacher Industry, consortium Semiconductor Research Corporation (SRC) Dev Pillai Industry Intel Corporation Tom Theis Industry IBM...beyond scaling.” IBM J. Res. & Dev . 50 (4/5):339-361. Han, Jiawei, and Micheline Kamber. 2011. Data mining: Concepts and Techniques. 3rd ed...Nature 472:167. Peng, Nie. 2010. “China’s first IOT industry fund set up in Jiangsu.” China Daily. Perry, Tekla. 2011. “Morris Chang: Foundry Father

  12. Defense Acquisition University Program Managers Tool Kit

    Science.gov (United States)

    2011-01-01

    22 Procurement Appropriations (Account Numbers and Budget Activities) ................ 23–24 Research, Dev ., Test, and Eval...BA 4 Adv. Comp. Dev . and Prototypes amount amount 6.5 BA 5 System Devel. and Demo. appropriated appropriated 6.6 BA 6 RDT&E Management Support...Testing with . . . (To Include the Mod Kits used for Testing) Is DT or IOT &E Required? Procurement $ YES RDT&E $ NO RDT&E Development Costs of PME

  13. F-35 Joint Strike Fighter Aircraft (F-35)

    Science.gov (United States)

    2013-12-01

    Authority/Budget Activity BY - Base Year DAMIR - Defense Acquisition Management Information Retrieval Dev Est - Development Estimate DoD - Department...BlocK 3F Fleet Release ~)II USNIOC • Completed IOT &E .,. Full Rate Production Decision .,. DAB Milestone c ~· F-35 Engine See Note...F-35 Aircraft Milestones SAR Baseline Dev Est Current APB Development Objective/Threshold Current Estimate Concept Demonstration Contract Award

  14. Remote Minehunting System (RMS)

    Science.gov (United States)

    2013-12-01

    Activity BY - Base Year DAMIR - Defense Acquisition Management Information Retrieval Dev Est - Development Estimate DoD - Department of Defense DSN - Defense...Milestones SAR Baseline Dev Est Current APB Development Objective/Threshold Current Estimate Milestone II DEC 1999 DEC 1999 JUN 2000 DEC 1999 OA...updated and will be re-assessed for MS C to align RMS with the LCS MCM MP IOT &E in September 2015. Acronyms and Abbreviations DOT&E - Director

  15. Warfighter Information Network-Tactical Increment 3 (WIN-T Inc 3)

    Science.gov (United States)

    2013-12-01

    Procurement Unit Cost BA - Budget Authority/Budget Activity BY - Base Year DAMIR - Defense Acquisition Management Information Retrieval Dev Est...UNCLASSIFIED 7 Schedule Milestones SAR Baseline Dev Est Current APB Development Objective/Threshold Current Estimate Milestone B...Milestone C MAY 2013 MAR 2015 SEP 2015 MAR 2017 1 (Ch-1) Initial Operational Test ( IOT ) - Start MAR 2016 JAN 2018 JUL 2018 NOV 2018 1 Initial

  16. Integrated Air and Missile Defense (IAMD)

    Science.gov (United States)

    2013-12-01

    Base Year DAMIR - Defense Acquisition Management Information Retrieval Dev Est - Development Estimate DoD - Department of Defense DSN - Defense...Schedule Milestones SAR Baseline Dev Est Current APB Development Objective/Threshold Current Estimate MS B DEC 2009 DEC 2009 JUN...2010 DEC 2009 CDR AUG 2011 MAY 2012 MAY 2013 MAY 2012 MS C DEC 2014 JUN 2015 JUN 2016 AUG 2016 1 (Ch-1) IOT &E Start JAN 2016 MAR 2016 MAR 2017 OCT 2017

  17. Patriot/Medium Extended Air Defense System Combined Aggregate Program (Patriot/MEADS CAP)

    Science.gov (United States)

    2013-12-01

    FUE - First Unit Equipped IOT &E - Initial Operational Test and Evaluation Missile Milestones SAR Baseline Dev Est Current APB Development...Acquisition Management Information Retrieval Dev Est - Development Estimate DoD - Department of Defense DSN - Defense Switched Network Econ...Milestone c FUE IOT &E Start Complete Full Rate Production Deci... AcQuisition Increment 2 Milestone C Lightweight Launcher FUE IOT &E Start

  18. Designing for Supportability: Driving Reliability, Availability, and Maintainability In...

    Science.gov (United States)

    2012-04-01

    the initial operational test and evaluation ( IOT &E) process, and assessed against defined criteria. As illustrated in Figure 1, total ownership costs...Affordability Supportability Design Reviews, Tests and Evaluation ASR PDR CDR IOT &E Figure 2. Reliability, Availability, Maintainability —Life...Expended Cost Committed Concept & Engineering & Prod & Operations & Tech Dev Manufacturing Depl’mnt FRP Support Dev Decision OT&E Review A B C

  19. KC-46A Tanker Modernization (KC-46A)

    Science.gov (United States)

    2013-12-01

    Defense Acquisition Management Information Retrieval Dev Est - Development Estimate DoD - Department of Defense DSN - Defense Switched Network Econ... Dev Est Current APB Development Objective/Threshold Current Estimate Milestone B and Contract Award FEB 2011 FEB 2011 FEB 2011 FEB 2011...Milestone C AUG 2015 AUG 2015 AUG 2016 AUG 2015 IOT &E Start MAY 2016 MAY 2016 MAY 2017 MAY 2016 FRP Decision JUN 2017 JUN 2017 JUN 2018 JUN 2017 RAA AUG 2017

  20. The Engineering Design of Engine/Airframe Integration for the SAENGER Fully Reusable Space Transportation System

    Science.gov (United States)

    2010-09-01

    Z39-18 1.0 THE GERMAN HYPERSONICS TECHNOLOGY PROGRAM (1988-1995) Fig. 01 SÄNGER/ HTP : Schedule of the German Hypersonics Activities In Germany...Concept Study Preliminary Study  System Study  Propulsion Study  Concept Studies  Basic Technologies  Test facilities  Techn. Dev.+Verific. Concept...Flight Test Vehicle Study  RAM-Engine Dev./Ground Test , SCRAM  Materials/Structures Technology The Engineering Design of Engine/Airframe

  1. Exclusive Multipotency and Preferential Asymmetric Divisions in Post-Embryonic Neural Stem Cells of the Fish Retina

    OpenAIRE

    Centanin, L.; Ander, J.-J.; Hoeckendorf, B.; Lust, K.; T. Kellner; Kraemer, I.; Urbany, C.; Hasel, E.; Harris, W.A.; Simons, B. D.; Wittbrodt, J

    2014-01-01

    This is the final version of the article. It has been published by The Company of Biologists Ltd in Development here: http://dev.biologists.org/content/early/2014/08/19/dev.109892.long. The potency of post-embryonic stem cells can only be addressed in the living organism, by labeling single cells after embryonic development and following their descendants. Recently, transplantation experiments involving permanently labeled cells revealed multipotent neural stem cells (NSCs) of embryonic or...

  2. Checkpoint Kinase-Dependent Regulation of DNA Repair and Genome Instability in Breast Cancer

    Science.gov (United States)

    2009-06-01

    Slaaby, A. M. Carr, and O. Nielsen. 2005. Ddb1 controls genome stability and meiosis in fission yeast. Genes Dev 19:853-62. 13. Hook, S. S., J. J. Lin...stability and meiosis in fission yeast. Genes Dev. 19:853–862. 26. Hu, J., C. M. McCall, T. Ohta, and Y. Xiong. 2004. Targeted ubiquitination of CDT1 by

  3. Estimation of wave forces on a tethered spherical float using potential flow theory

    Digital Repository Service at National Institute of Oceanography (India)

    Vethamony, P.; Chandramohan, P.; Sastry, J.S.

    stream_size 9 stream_content_type text/plain stream_name Proc_Int_Conf_Coast_Port_Eng_Dev_Countries_1991_1442.pdf.txt stream_source_info Proc_Int_Conf_Coast_Port_Eng_Dev_Countries_1991_1442.pdf.txt Content-Encoding ISO-8859...-1 Content-Type text/plain; charset=ISO-8859-1 ...

  4. SECURITY FOR DEVOPS DEPLOYMENT PROCESSES: DEFENSES, RISKS, RESEARCH DIRECTIONS

    OpenAIRE

    Norman Wilde; Brian Eddy; Khyati Patel; Nathan Cooper; Valeria Gamboa; Bhavyansh Mishra; Keenal Shah

    2016-01-01

    DevOps is an emerging collection of software management practices intended to shorten time to market for new software features and to reduce the risk of costly deployment errors. In this paper we examine thesecurity implications of two of the key DevOps practices, automation of the deployment pipeline using adeployment toolchain and infrastructure-as-code to specify the environment of the deployed software. Wefocus on identifying what changes when an organization moves from manual deployments...

  5. Organizational Culture - Education of the Department of Defense Program Managers Under Defense Acquisition Workforce Improvement Act

    Science.gov (United States)

    1993-01-01

    6 , 7= 24 Mar 94 SPSS for MS WINDOWS Release 6.0 Page 9 MBTI: 7 INFP PERRY1 Perry Level Mean 385.133 Median 391.000 Mode 400.000 Std dev 39.987...Variance 1598.981 Range 133.000 Minimum 292.000 Maximum 425.000 Valid cases 15 Missing cases 0 *! MBTI: 7 INFP 7- 6 5 4- 3- 1 $td. Dev x 39.99 Mean = 385.1

  6. Water Quality And Sediment Evaluation for Inner Harbor Navigation Canal Lock Replacement Project, New Orleans, Louisiana

    Science.gov (United States)

    2011-08-01

    dredge effluent, elutriate tests are conducted using site water from the dredging site. In this case, some sites that are presently marine in char ...observed significantly higher mortality of Hyalella azteca in DMMUs 5 NN and 7 NN was, at least partially , a response to the relatively elevated...solid phase bioaccumulation tests. DMMU/Site Percent Survival Final Biomass (g) Batch Mean Std. Dev Mean Std. Dev 3 NN 95 4 27.5 2.9 2 3 N 96 3

  7. Generic Abstraction of Hardware Control Based on the ALMA Common Software

    Science.gov (United States)

    Jeram, B.; Chiozzi, G.; Ibsen, J.; Cirami, R.; Pokorny, M.; Muders, D.; Wischolek, D.

    2004-07-01

    The ALMA Common Software (ACS) is a CORBA-based framework that provides a common and homogeneous infrastructure for the whole ALMA software, from high-level data flow applications down to instrument control (Schwarz et al., 2004). This paper focuses on ACS support for the development of Control System applications. In this domain, ACS provides a generic abstraction of hardware control and monitor points that is independent of the software underneath. This abstraction layer is coupled to the hardware using the DevIO (Device Input/Output) interface, based on the Bridge design pattern. Application developers have to implement DevIO classes that handle the details of the communication with the hardware. ACS itself provides a default DevIO implementation which simply writes and reads into/from a memory location. Currently there are two other major DevIO implementations available: a CAN bus communication, used by ALMA, and a socket based implementation used by the Atacama Pathfinder EXperiment (APEX) project. In spite of using different hardware and control electronics, the DevIO abstraction allows the ALMA and APEX projects to have the same device architecture down to the level of the DevIO implementation.

  8. Uptake of Zn2+ ions by a fully iron-exchanged clinoptilolite. Case study of heavily contaminated drinking water samples.

    Science.gov (United States)

    Dimirkou, Anthoula

    2007-06-01

    Clinoptilolite, a natural zeolite, was used for the synthesis of a high surface area clinoptilolite (Clin)-iron (Fe) oxide system, in order to be used for the removal of Zn(2+) ions from drinking water samples. The new system was obtained by adding natural Clin in an iron nitrate solution under strongly basic conditions. The Clin-Fe system has specific surface area equal to 151 m(2)/g and is fully iron exchanged (Fe/Al=1.23). Batch adsorption experiments were carried out to determine the effectiveness of the Clin and the Clin-Fe system in removal of Zn from drinking water. Adsorption experiments were conducted by mixing 1.00 g of each of the substrates with certain volume of water samples contaminated with ten different Zn concentrations (from 7.65x10(-5) to 3.82x10(-2)M or from 5.00 to 2500 ppm Zn). For our experimental conditions, the maximum adsorbed Zn amount by Clin was 71.3mg/g, whereas by the Clin-Fe system 94.8 mg/g. The main factors that contribute to different adsorbed Zn amounts by the two solids are due to new surface species and negative charge of the Clin-Fe system. In addition, the release of counterbalanced ions (i.e. Ca(2+), Mg(2+), Na(+) and K(+)) was examined, as well as the dissolution of framework Si and Al. It was found that for most of the samples the Clin-Fe system releases lower concentrations of Ca, Mg and Na and higher concentrations of K than Clin, while the dissolution of Si/Al was limited. Changes in the composition of water samples, as well as in their pH and conductivities values were reported and explained.

  9. A Comparison of Risperidone and Buspirone for Treatment of Behavior Disorders in Children with Phenylketonuria

    Directory of Open Access Journals (Sweden)

    Afshin FAYYAZI

    2014-12-01

    and Lang W .Neurobehavioral Problems Associated with Phenylketonuria. Psychiatry (Edgemont 2009; 7(12:29–32.Luciana M, Hanson K L,Whitley C B.A preliminary report on dopamine system reactivity in PKU: acute effects of haloperidol on neuropsychological, physiological, and neuroendocrine functions. Psychopharmacology 2004;175: 18–25.Pappadopulos E, Woolston S, Chait A, Perkins M, Connor DF, Jensen P S. Pharmacotherapy of Aggression in Children and Adolescents: Efficacy and Effect Size. J CDN ACAD Child Adolesc Psychiatry 2006; 15(1:27-39.Shea S, Turgay A, Carroll A, Schulz M, Orlik H ,Smith I and et al. Risperidone in the Treatment of Disruptive Behavioral Symptoms in Children With Autistic and Other Pervasive Developmental Disorders. Pediatrcs 2004; 114:634-641.Miral S, Gencer O, Inal-Emiroglu F.N, Baykara B, Baykara A, Dirik E. Risperidone versus haloperidol in children and adolescents with AD: a randomized, controlled, doubleblind trial. Eur Child Adolesc Psychiatry 2008; 17:1–8.Aman M.G, Hollway J.A, McDougle C.J, Scahill L, Tierney E, McCracken J.T and et al. Cognitive effects of risperidone in children with autism and irritable behavior. J. Child Adolesc. Psychopharmacol 2008; 18:227–236.Pandina G.J, Bossie C.A, Youssef E, Zhu Y, Dunbar F. Risperidone improves behavioral symptoms in children with autism in a randomized, double-blind, placebocontrolled trial. J Autism Dev Disord 2007; 37:367–373.Luby J, Mrakotsky C, Stalets M.M, Belden A, Heffelfinger A, Williams M and et al. Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy. J. Child Adolesc. Psychopharmacol 2006; 16:575–587.Nagaraj R, Singhi P, Malhi P. Risperidone in children with autism: randomized, placebo controlled, double blind study. J. Child Neurol 2006; 21:450–455.Haas M, Karcher K, Pandina GJ. Treating Disruptive Behavior Disorders with Risperidone: A 1-Year, Open-Label Safety Study in Children and Adolescents. Journal of Child and

  10. Expression and characterization of UL16 gene from duck enteritis virus

    Directory of Open Access Journals (Sweden)

    Wang Mingshu

    2011-08-01

    Full Text Available Abstract Background Previous studies have indicated that the UL16 protein and its homologs from herpesvirus were conserved and played similar roles in viral DNA packaging, virion assembly, budding, and egress. However, there was no report on the UL16 gene product of duck enteritis virus (DEV. In this study, we analyzed the amino acid sequence of UL16 using bioinformatics tools and expressed in Escherichia coli Rosetta (DE3 induced by isopropy1-β-D-thiogalactopyranoside (IPTG. The recombinant protein was produced, purified using a Ni-NTA column and used to generate the polyclonal antibody against UL16. The intracellular distribution of the DEV UL16 product was carried out using indirect immunofluorescence assay. Results In our study, UL16 gene of DEV was composed of 1089 nucleotides, which encoded 362 amino acids. Multiple sequence alignment suggested that the UL16 gene was highly conserved in herpesvirus family. The UL16 gene was cloned into a pET prokaryotic expression vector and transformed into Escherichia coli Rossetta (DE3 induced by IPTG. A 60kDa fusion protein band corresponding to the predicted size was produced on the SDS-PAGE, purified using a Ni-NTA column. Anti-UL16 polyclonal sera was prepared by immunizing rabbits, and reacted with a band in the IPTG induced cell lysates with an apparent molecular mass of 60 kDa. In vivo expression of the UL16 protein in DEV infected duck embryo fibroblast cells (DEFs was localized mostly around perinuclear cytoplasmic area and in cytosol using indirect immunofluorescence assay. Conclusions The UL16 gene of DEV was successfully cloned, expressed and detected in DEV infected DEFs for the first time. The UL16 protein localized mostly around perinuclear cytoplasmic area and in cytosol in DEV infected DEFs. DEV UL16 shared high similarity with UL16 family members, indicating that DEV UL16 many has similar function with its homologs. All these results may provide some insight for further research about

  11. Autism Spectrum Disorders in Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Reza MOHAMMADI

    2011-12-01

    2007; 28: 235-258.Zaroff CM, Uhm SY. Prevalence of autism spectrum disorders and influence of country of measurement and ethnicity. Soc Psychiatry Psychiatr Epidemiol 2011;published online.Baron-Cohen S, Scott FJ, Allison C, Williams J, Bolton P, Matthews FE, et al. Prevalence of autism-spectrum conditions: UK school-based population study. Br J Psychiatry 2009;194:500-509.Brugha TS, McManus S, Bankart J, Scott F, Purdon S, SmithJ, et al. Epidemiology of autism spectrum disorders inadults in the community in England. Arch Gen Psychiatry 2011; 68: 459-465.Prevalence of autism spectrum disorders - Autism and Developmental Disabilities Monitoring Network, United States, 2006. MMWR Surveill Summ 2009; 58: 1-20.Fombonne E. Epidemiology of pervasive developmental disorders. Pediatr Res 2009; 65: 591-598.Ehlers S, Gillberg C. The epidemiology of Asperger syndrome. A total population study. J Child Psychol Psychiatry 1993; 34: 1327-1350.Kadesjo B, Gillberg C, Hagberg B. Brief report: autismand Asperger syndrome in seven-year-old children: a totalpopulation study. J Autism Dev Disord 1999; 29: 327-331.Williams JG, Higgins JP, Brayne CE. Systematic reviewof prevalence studies of autism spectrum disorders. ArchDis Child 2006; 91: 8-15.Bernier R, Mao A, Yen J. Psychopathology, families, andculture: autism. Child Adolesc Psychiatr Clin N Am 2010;19: 855-867.Shamsi-pour M, Yonesian M, Mansouri A. Epidemiologyof autism: recent challenges in prevalence of autism andits risk factors. Journal of health and knowledge 2010; 5:133.Ghanizadeh A. A preliminary study on screening prevalence of pervasive developmental disorder in school children in Iran. J Autism Dev Disord 2008; 38:759-763.Nejatisafa AA, Kazemi MR, Alaghebandrad J. Autisticfeatures in adult population: evidence for continuity ofautistic symptoms with normality. Advanced in cognitivescience 2003; 5: 34-39.Khoushabi K, Pouretemad HR. Prevalence of pervasive developmental disorders according to gender in a sampleof Iranian

  12. Sodium Channel Gene Mutations in Children with GEFS+ and Dravet Syndrome: A Cross Sectional Study

    Directory of Open Access Journals (Sweden)

    Seyed Hassan TONEKABONI

    2013-06-01

    before age of one year and psychomotor retardation after age of two years are the most significant criteria in SCN1A mutation positive patients.References Dravet C, Bureau M, Oguni H, Fukuyama Y, Cokar O.Severe myoclonic epilepsy in infancy (Dravet syndrome. In: Roger J, Bureau M, Dravet C, Genton P, Tassinari CA, Wolf P, eds. Epileptic Syndromes in Infancy, Childhood and Adolescence, 4th  ed. London: John Libbey Eurotext Publishers; 2005. p. 89-113.Dalla Bernardina B, Colamaria V, Capovilla G, Bondavalli S. Nosological classification of epilepsies in the first three years years of life. Prog Clin Biol Res 1983;124:165-83.Commission on Classification and Terminology of the International League against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989;30:389-99.Scheffer IE, Zhang. YH, Jansen FE, Dibbens L. Dravet syndrome or genetic (generalized epilepsy with febrile seizures plus? Brain Dev 2009;31(5:394-400.Singh R, Andermann E, Whitehouse WP, Harvey AS, Keene DL, Seni MH, et al. severe myoclonic epilepsy of infancy: extended spectrum of GEFS+? Epilepsia 2001;42(7:837-44.Scheffer IE, Harkin LA, Dibbens LM, Mulley JC, Berkovic SF. Neonatal epilepsy syndromes and generalized epilepsy with febrile seizures plus (GEFS+. Epilepsia 2005;46 Suppl 10:41-7.Harkin LA, McMahon JM, Iona X, Dibbens L, Pelekanos JT, Zuberi SM, et al. The spectrum of SCN1A-related infantile enceptic encephalopathies. Brain 2007;130(Pt 3:843-52.Sun H, Zhang Y, Liang J, Liu X, Ma X, Qin, et al. Seven novel SCN1A mutations in Chinese patients with severe myoclonic epilepsy of infancy. Epilepsia 2008;49:1104-7.Miller SA, Dykes DD, polesky HF. A simple salting out procedure  for  extracting  DNA from  human  cucleated Nucleated cells. Nucleic Acids Res 1988;16(3:2115.Marini C, Scheffer IE, Nabbout R, Mei D, Cox K, Dibbens LM, et al. SCN1A duplications and deletions detected in dravet syndrome: implications for molecular diagnosis. Epilepsia 2009; 50

  13. Framework for automatic information extraction from research papers on nanocrystal devices.

    Science.gov (United States)

    Dieb, Thaer M; Yoshioka, Masaharu; Hara, Shinjiro; Newton, Marcus C

    2015-01-01

    To support nanocrystal device development, we have been working on a computational framework to utilize information in research papers on nanocrystal devices. We developed an annotated corpus called " NaDev" (Nanocrystal Device Development) for this purpose. We also proposed an automatic information extraction system called "NaDevEx" (Nanocrystal Device Automatic Information Extraction Framework). NaDevEx aims at extracting information from research papers on nanocrystal devices using the NaDev corpus and machine-learning techniques. However, the characteristics of NaDevEx were not examined in detail. In this paper, we conduct system evaluation experiments for NaDevEx using the NaDev corpus. We discuss three main issues: system performance, compared with human annotators; the effect of paper type (synthesis or characterization) on system performance; and the effects of domain knowledge features (e.g., a chemical named entity recognition system and list of names of physical quantities) on system performance. We found that overall system performance was 89% in precision and 69% in recall. If we consider identification of terms that intersect with correct terms for the same information category as the correct identification, i.e., loose agreement (in many cases, we can find that appropriate head nouns such as temperature or pressure loosely match between two terms), the overall performance is 95% in precision and 74% in recall. The system performance is almost comparable with results of human annotators for information categories with rich domain knowledge information (source material). However, for other information categories, given the relatively large number of terms that exist only in one paper, recall of individual information categories is not high (39-73%); however, precision is better (75-97%). The average performance for synthesis papers is better than that for characterization papers because of the lack of training examples for characterization papers

  14. Psychiatric Aspects of Childhood Epilepsy

    Directory of Open Access Journals (Sweden)

    Raman Deep PATTANAYAK

    2012-06-01

    2004;3(11:663-72.20. Bujoreanu, IS, Ibeziako P, DeMaso DR. Psychiatric concerns in pediatric epilepsy. Child Adolesc Psychiatr Clin N Am 2010;19(2:371-86.21. Hermann BP, Lin, JJ, Jones, JE, Seidenberg S. The emerging architecture of neuropsychological impairment in epilepsy. Neurol Clin 2009;27(4:881-907.22. Hermann B, Seidenberg M, Bell B, Rutecki P, Sheth R, Ruggles K, et al. The neurodevelopmental impact of childhood-onset temporal lobe epilepsy on brain structure and function. Epilepsia 2002;43(9:1062-71.23. Loring DW, Meador KJ. Cognitive side effects of antiepileptic drugs in children. Neurology 2004;62(6:872-7.24. McDermott S, Mani S, Krishnaswami S. A populationbased analysis of specific behavior problems associated with childhood seizures. J Epilepsy 1995;8:110-8.25. Davies S, Heyman I, Goodman, R. A population survey of mental health problems in children with epilepsy. Dev Med Child Neurol 2003;45(5:292-5.26. Kaufmann R, Goldberg-Stern H, Shuper A. Attentiondeficit disorders and epilepsy in childhood: incidence, causative relations and treatment possibilities. J Child Neurol 2009;24(6:727-33.27. Buelow JM, Austin JK, Perkins SM, Shen J, Dunn DW, Fastenau PS. Behavior and mental health problems in children with epilepsy and low IQ. Dev Med Child Neurol 2003;45(10:683-92.28.Williams J, Lange B, Phillips T, Sharp GB, DelosReyes E, Bates S, et al. The course of inattentive and hyperactiveimpulsive symptoms in children with new onset seizures. Epilepsy Behav 2002;3(6:517-21.29. Hermann B, Seidenberg M, Jones J. The neurobehavioural comorbidities of epilepsy: can a natural history be developed? Lancet Neurol 2008;7(2:151-60.30. Schoenfeld J, Seidenberg M, Woodard A, Hecox K, Inglese C, Mack K, et al. Neuropsychological and behavioral status of children with complex partial seizures. Dev Med Child Neurol 1999;41(11:724-31.31. Austin JK, Caplan R. Behavioral and psychiatric comorbidities in pediatric epilepsy: toward an integrative

  15. Infantile Spasm: A Review Article

    Directory of Open Access Journals (Sweden)

    Mohammad Mahdi TAGHDIRI

    2014-07-01

    pres; 2009. p. 593-7.Fujii, Oquni H, Hirano Y, Shioda M, Osawa M. A longterm, clinical study on symptomatic infantile spasm with focal features. Brain Dev 2013;35(5:379-85.SankarR, Koh S, Wu J. Menkes JH. Paroxysmal disorders. In: Menkes JH, Sarnat HB,. MariaBL, editors Child neurology. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2006. p. 857-942.Kendall Nash and Joseph Sullivan. Myoclonic seizures and infantile spasms. InSwaiman KF, Ashwal S, Ferriero DM, Schor NF, editors.. Swaiman’s pediatric Neurology: principles and practice. 5th ed. Edinburgh: Elsevier Saunders; 2012. p. 774-89.Paroxysmal Disorders. In: Piña-Garza J. Fenichel’s Clinical Pediatric Neurology. 7th ed. Elsevier Saunders; 2013. p. 1-46.Paciorkowski AR, Thio LL, Dobyns WB. Genetic and biologic classification of infantile spasms. Pediatr Neurol 2011;45(6:355-67.Manqanno S, Nardello R, Tripi G, Giordano G, Spitaleri C, Manfano GR. West Syndrome Followed by juvenile myoclonic epilepsy: a coincidental occurrence. BMC Neural 2013;13:48.LUX AL. Latest American and European update on infantile spasms. Curr Neural Neurosci Rep 2013;13(3:334.Hrachovy RA, Frost JD Jr. Infantile spasms. Handb Clin Neuro. 2013;111:611-8.Shumiloff NA, Lam WM, Manasco KB. Adrenocorticotropic hormone for the treatment of west syndrome in children. Ann Pharmacother 2013 47(5:744- 54.Wheless JW, Gibson PA, Rosbeck KL, Hardin M, O’Dell C, Whiltemore V. Infantile Spasms (west syndrome:  Update and resources for pediatricians and providers to share with parents. BMC Pediatr. 2012;12:108.Watemberg N. Infantile Spasms: treatment challenges. Curr Treat Options Neural. 2012;14(4: 322-31.Fukui M, Shimakawa S, Tanabe T, Nomura S, Kashiwagi M, Azumakawa K. Partial seizures during ACTH therapy in a cryptogenic West syndrome patient. Brain Dev 2013;Pii:s0387-7604(1300003-x.Friedman D, Boqner M, Parker-Menzer K, Dviskyo. Vigabatin for partial- onset seizure treatment in patients with tuberous sclerosis complex. Epilepsy Behav 2013

  16. Clinical and Para clinical Manifestations of Tuberous Sclerosis: A Cross Sectional Study on 81 Pediatric Patients

    Directory of Open Access Journals (Sweden)

    Seyyed Hassan TONEKABONI

    2012-09-01

    -9.Lendvay TS, Marshall FF. The tuberous sclerosis complex and its highly variable manifestations. J Urol2003 May;169(5:1635-42.Curatolo P, Jóźwiak S, Nabbout R; on behalf of the participants of the TSC Consensus Meeting for SEGA and Epilepsy Management. Management of epilepsy associated with tuberous sclerosis complex (TSC:Clinical recommendations. Eur J Paediatr Neurol 2012Jun;16(1:83-5.Jansen FE, Van Huffelen AC, Van Rijen PC, LeijtenFS,Jennekens-Schinkel A, Gosselaar P et al. Epilepsy surgeryin tuberous sclerosis: the Dutch experience. Seizure 2007Jul;16(5:445-53.Turgut M, Akalan N, Ozgen T, Ruacan S, Erbengi A. Subepandymal giant cell astrocytoma associated with tuberous sclerosis: diagnostic and surgical characteristics of five cases with unusual features. Clin Neurol Neurosurg1996 Aug;98(3:217-21.Coppola G, Klepper J, Ammendola E, Fiorillo M, dellaCorte, Capano G. The effects of the ketogenic diet in refractory partial seizures with reference to tuberous sclerosis. Eur J Pediatr Neurol 2006 May;10(3:148-51.Jozwia S, Kotulska K, Domanska-Pakiela D, LojszczykB, Syczewska M et al. Antiepileptic treatment before the onset of seizure reduces epilepsy severity and risk of mental retardation in infants with tuberous sclerosis complex. Eur J Paediatr Neurol 2011 Sep;15(5:424-31.Konishi Y, Ito M, Okuno T, Hojo H, Okuda R, Nakano Yet al. Tuberous sclerosis: early neurologic manifestations and CT features in 18 patients. Brain Dev 1979;1(1:31-7.Gerard G, Weisberg L. Tuberous sclerosis: CT findings and differential diagnosis. Comput Radiol 1987 Jul-Aug;11(4:189-92.Pompili G, Zirpoli S, Sala C, Flor N, Alfano RM, Volpi A et al. Magnetic resonance imaging of renal involvementin genetically studied patients with tuberous sclerosis complex. Eur J Radiol 2009 Nov;72(2:335-41.Fleury P, de Groot Wp, Delleman JW, Verbeeten B Jr,Frankenmolen-Witkiezwicz IM. Tuberous sclerosis: theincidence of sporadic cases versus familial cases. BrainDev 1980;2(2:107-17.Saadat M, Ansari-Lari M, Farhud

  17. Dielectric elastomer vibrissal system for active tactile sensing

    Science.gov (United States)

    Conn, Andrew T.; Pearson, Martin J.; Pipe, Anthony G.; Welsby, Jason; Rossiter, Jonathan

    2012-04-01

    Rodents are able to dexterously navigate confined and unlit environments by extracting spatial and textural information with their whiskers (or vibrissae). Vibrissal-based active touch is suited to a variety of applications where vision is occluded, such as search-and-rescue operations in collapsed buildings. In this paper, a compact dielectric elastomer vibrissal system (DEVS) is described that mimics the vibrissal follicle-sinus complex (FSC) found in rodents. Like the vibrissal FSC, the DEVS encapsulates all sensitive mechanoreceptors at the root of a passive whisker within an antagonistic muscular system. Typically, rats actively whisk arrays of macro-vibrissae with amplitudes of up to +/-25°. It is demonstrated that these properties can be replicated by exploiting the characteristic large actuation strains and passive compliance of dielectric elastomers. A prototype DEVS is developed using VHB 4905 and embedded strain gauges bonded to the root of a tapered whisker. The DEVS is demonstrated to produce a maximum rotational output of +/-22.8°. An electro-mechanical model of the DEVS is derived, which incorporates a hyperelastic material model and Euler- Bernoulli beam equations. The model is shown to predict experimental measurements of whisking stroke amplitude and whisker deflection.

  18. Frequency, Causes, and Findings of Brain CT Scans of Neonatal Seizure at Besat Hospital, Hamadan, Iran

    Directory of Open Access Journals (Sweden)

    Fateme EGHBALIAN*

    2015-01-01

    . Clin perinatal 2005; 24: 735-772.Lanska MJ, Lanska DJ, Baumann RJ, Kryscio RJ. A population-based study of neonatal seizures in Fayette County, Kentucky. Neurology 1995; 45:724-32.Ronen GM, Penney S, Andrews W. The epidemiology of clinical neonatal seizures in Newfoundland: a populationbased study. J Pediatr 1999; 134:71-5.Saliba RM, Annegers JF, Waller DK, et al. Incidence of neonatal seizures in Harris County, Texas, 1992-1994. Am J Epidemiol 1999; 150:763-9.Volpe JJ. Neonatal seizures. In: Neurology of the newborn. 5th ed. Philadelphia: WB Saunders. 2008. P. 203-44.Fanaroff AA, Martin RJ, Neonatal. Prenatal medicine. 8th ed. New York: Mosby, 2006; 956-976.Scher MS, Aso K, Beggarly ME, et al. Electrographic seizures in preterm and full-term neonates: clinical correlates, associated brain lesions, and risk for neurologic sequelae. Pediatrics 1993; 91:128-34.Tekgul H, Gauvreau K, Soul J, et al. The current etiologic profile and neurodevelopmental outcome of seizures in term newborn infants. Pediatrics 2006; 117:1270-80.Rogalski LI, Minokoshi M, Silveira DC, Cha BH, Holmes GL. Recurrent neonatal seizures: relationship of pathology to the electroencephalogram and cognition. Brain Res Dev Brain Res 2001; 129:27-38.Cilio MR, Sogawa Y, Cha BH, Liu X, Huang LT, Holmes GL. Long-term effects of status epilepticus in the immature brain are specific for age and model. Epilepsia 2003; 44:518-28.Lynch M, Sayin U, Bownds J, Janumpalli S, Sutula T. Long-term consequences of early postnatal seizures on hippocampal learning and plasticity. Eur J Neurosci 2000; 2:2252-64.Ni H, Jiang YW, Bo T, Wang JM, Wu XR. c-Fos, N-methyl-Diaspartate receptor 2C, GABA-A-a1 immunoreactivity, seizure latency, and neuronal injury following single or recurrent neonatal seizures in hippocampus of Wistar rat. Neurosci Lett 2005; 380:149-54.Bo T, Jiang Y, Cao H, Wang J, Wu X. Long-term effects of seizures in neonatal rats on spatial learning ability and N-methyl-D-aspartate receptor expression in the brain

  19. Disease: H01154 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available a type electrocardiographic changes induced by concomitant use of lithium and propafenone in patient with Wolff-Parkinson-White syndrome. Pacing Clin Electrophysiol 30:823-5 (2007) ...

  20. Main: MPB4 [TP Atlas

    Lifescience Database Archive (English)

    Full Text Available tructural knowledge. Nat. Immunol.|J. Clin. Immunol.|Cell. Mol. Immunol.|Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci.|FEBS Lett. 19067132|18087252|20118971|20551597|21420960 MPB4.csml ...

  1. Disease: H00045 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available rug) Skeel RT (ed). Handbook of Cancer Chemotherapy, Sixth Edition Lippincott Williams & Wilkins (2003) ... ...lity of Ki-67 as a prognostic marker in pancreatic endocrine neoplasms. Am J Clin Pathol 109:245-7 (1998) (d

  2. An open-label study to assess the effect of a single dose of Nebivolol and Ivabradine on heart rate and pulse wave velocity in hypertensive patients receiving amlodipine

    Directory of Open Access Journals (Sweden)

    Rama Mohan Pathapati

    2015-04-01

    Conclusions: Nebivolol is an effective HR lowering agent compared to Ivabradine. However, significant decrease in arterial stiffness was observed with Ivabradine. [Int J Basic Clin Pharmacol 2015; 4(2.000: 219-223

  3. Study of prescription pattern and adverse drug reactions in patients with cervical cancer in tertiary care teaching institute

    Directory of Open Access Journals (Sweden)

    Ankita Sunilrao Jire

    2016-08-01

    Conclusions: Among patients with CA cervix, cisplatin was most commonly prescribed drug. Nausea was most common ADR which is of and lsquo;mild level 1' severity. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1594-1597

  4. Effect of nimodipine and flunarizine on neuromuscular function in mice

    Directory of Open Access Journals (Sweden)

    Swapnil B. Kaikade

    2016-08-01

    Conclusions: Nimodipine has significant dose dependent depressant action on neuromuscular function while flunarizine has no effect on the above mentioned parameter. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1524-1527

  5. Drug utilization pattern of analgesics in various departments of a tertiary care teaching rural dental hospital

    Directory of Open Access Journals (Sweden)

    Nirav N. Patel

    2014-10-01

    Conclusions: Drug utilization data can help to formulate appropriate clinical guidelines for drug use and facilitate rational use of medicines in population. [Int J Basic Clin Pharmacol 2014; 3(5.000: 804-806

  6. Innovative first order elimination kinetics working model for easy learning

    Directory of Open Access Journals (Sweden)

    Navin Budania

    2016-06-01

    Conclusions: First order elimination kinetics is easily understood with the help of above working model. More and more working models could be developed for teaching difficult topics. [Int J Basic Clin Pharmacol 2016; 5(3.000: 862-864

  7. Clinical Evaluation of the Joints of Patients with Hemophilia

    Directory of Open Access Journals (Sweden)

    Sezai Ozkan

    2014-08-01

    Conclusion: Treatment and monitoring of patients with hemophilia requires a multidisciplinary approach. Early diagnosis, treatment, rehabilitation and a constant monitoring will be effective in preventing arthropaty. [Arch Clin Exp Surg 2014; 3(4.000: 233-239

  8. A randomized, open-labelled study of the sedative, analgesic and anxiolytic effect of dexmedetomidine and tramadol in postoperative patients

    Directory of Open Access Journals (Sweden)

    Padma L

    2013-12-01

    Conclusion: Though there is no statistical difference in both groups, dexmedetomidine significantly reduced anxiety, agitation and produced calmness in postoperative patients which was not seen with tramadol. [Int J Basic Clin Pharmacol 2013; 2(6.000: 804-809

  9. Disease: H01104 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ination of lymphatic filariasis: do we have the drugs to complete the job? Curr Opi...rica--treatment challenges and prospects. Clin Microbiol Infect 17:977-85 (2011) PMID:20847694 (description) Bockarie MJ, Deb RM Elim

  10. Cardiovascular and biochemical studies on the effects of thrombin and dabigatran and the interaction with vasopressor molecules

    Directory of Open Access Journals (Sweden)

    R. Anand

    2014-10-01

    Conclusion: The thrombin inhibitor, dabigatran reduces vascular oxidative stress and inflammation, improves endothelial function, and decreases atherosclerosis in rodents. [Int J Basic Clin Pharmacol 2014; 3(5.000: 874-878

  11. Role of glipizide therapy on oxidative stress parameters in the patient with Type-II diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Prakash P. Malam

    2014-12-01

    Conclusion: Glipizide therapy significantly reduced oxidative free radicals and increased antioxidant mechanism, which reduced oxidative stress, progression DM-II and its related complication. [Int J Basic Clin Pharmacol 2014; 3(6.000: 995-999

  12. The efficacy and safety of clomiphene citrate and metformin on ovulation induction in patients suffering from anovulatory infertility

    Directory of Open Access Journals (Sweden)

    Hardik Patel

    2015-12-01

    Conclusion: Ovulation rate was significantly higher compared to pregnancy rate. We could not find any benefit of adding metformin to the standard treatment with clomiphene citrate. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1241-1246

  13. Effects of calcium channel blocker, nifedipine, on antidepressant activity of fluvoxamine, venlafaxine and tianeptine in mice

    Directory of Open Access Journals (Sweden)

    Ashok K. Sharma

    2015-02-01

    Conclusions: Nifedipine, fluvoxamine, venlafaxine and tianeptine possess antidepressant activity and nifedipine exhibits synergistic antidepressant activity with fluvoxamine, venlafaxine and tianeptine. [Int J Basic Clin Pharmacol 2015; 4(1.000: 82-88

  14. Aortic valve replacement outcome using upper ministernotomy: A prospective comparison of the upper ministernotomy and conventional full median sternotomy

    Directory of Open Access Journals (Sweden)

    Atsushi Tamura

    2015-04-01

    Conclusions: Although ministernotomy can be safely used for AVR without prolonging operative or cardiopulmonary time, no significant advantages were discerned for choosing ministernotomy over conventional full median sternotomy. [Arch Clin Exp Surg 2015; 4(2.000: 69-73

  15. Comparison of efficacy of telmisartan with losartan in patients of essential hypertension with cognitive impairment

    Directory of Open Access Journals (Sweden)

    Nitin Natthuji Puram

    2016-06-01

    Conclusions: Telmisartan is as effective as losartan in controlling blood pressure and improving cognitive function in hypertensive patients with cognitive impairment. [Int J Basic Clin Pharmacol 2016; 5(3.000: 702-706

  16. A comparative study of efficacy of intravenous dexmedetomidine and intravenous esmolol for attenuation of stress response during laryngoscopy and endotracheal intubation

    Directory of Open Access Journals (Sweden)

    Hema B. Gupta

    2016-10-01

    Conclusions: Dexmedetomidine 1 and #956;g/kg is more effective than esmolol for attenuating the hemodynamic response to laryngoscopy and intubation in elective surgical patients. [Int J Basic Clin Pharmacol 2016; 5(5.000: 1803-1808

  17. Disease: H01041 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available s to gram-positive coccus. Most infections are mild, but fatal infections such as endocarditis with high rat...ococcus urinae: severe and fatal bloodstream infections and endocarditis. J Clin

  18. Keloids

    Science.gov (United States)

    ... 2012:chap 98. Ud-Din S, Bayat A. New insights on keloids, hypertrophic scars, and striae. Dermatol Clin . ... ADAM Health Solutions. About MedlinePlus Site Map FAQs Customer Support Get email updates Subscribe to RSS Follow ...

  19. Genetics Home Reference: primary carnitine deficiency

    Science.gov (United States)

    ... Majdalani M. Primary carnitine deficiency: novel mutations and insights into the cardiac phenotype. Clin Genet. 2014 Feb; ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  20. Genetics Home Reference: Smith-Lemli-Opitz syndrome

    Science.gov (United States)

    ... Citation on PubMed Yu H, Patel SB. Recent insights into the Smith-Lemli-Opitz syndrome. Clin Genet. ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  1. Disease: H00245 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ing receptor mutations. Best Pract Res Clin Rheumatol 22:129-48 (2008) PMID:11706743 Heath DA Familial hypoc...200 146200 PMID:18328986 Egbuna OI, Brown EM Hypercalcaemic and hypocalcaemic conditions due to calcium-sens

  2. Disease: H00322 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ettsial infections--a threat to travellers? Curr Opin Infect Dis 17:433-7 (2004) PMID:15546086 Jensenius M, ...Fournier PE, Raoult D Rickettsioses and the international traveler. Clin Infect D

  3. Disease: H01084 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available [Bordetella holmesii bacteremia in a child with sickle cell disease]. Enferm Infecc Microbiol Clin 29:779-80...Saint Jean M, Brun D, Guiso N, Bekal S, Ovetchkine P, Tapiero B Bordetella holmesii bacteremia in asplenic child

  4. Drug utilization pattern of antidiabetic agents in a tertiary care hospital of western Odisha, India

    Directory of Open Access Journals (Sweden)

    Ratna Agrawal

    2016-10-01

    Conclusions: The prescribing trend has been monotherapy with insulin followed by oral antidiabetic drugs in the form of glimepiride and metformin combination. [Int J Basic Clin Pharmacol 2016; 5(5.000: 2222-2226

  5. Impact of teaching session on concepts of palliative care in medical undergraduates.

    Directory of Open Access Journals (Sweden)

    Sirisha Annavarapu

    2016-02-01

    Conclusions: Concept of palliative care was poor among medical undergraduates. Health care providers can overcome by knowledge construction, interrelation between practice and evidence based medicine. [Int J Basic Clin Pharmacol 2016; 5(1.000: 188-191

  6. Disease: H00471 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00471 Split-hand/foot malformation (SHFM) Split hand/foot malformation (SHFM) is a...9 (description, gene) Elliott AM, Evans JA, Chudley AE Split hand foot malformation (SHFM). Clin Genet 68:50

  7. Oral premedication with pregabalin and clonidine for hemodynamic stability during laryngoscopy: A comparative study

    Directory of Open Access Journals (Sweden)

    Asmita Chaudhary

    2015-04-01

    Conclusion: Hemodynamic pressure response of airway instrumentation was attenuated with pregabalin and clonidine oral premedication without prolongation of recovery time and side effects. [Int J Basic Clin Pharmacol 2015; 4(2.000: 294-299

  8. C1 esterase inhibitor

    Science.gov (United States)

    ... algorithm for the diagnosis, therapy and management of hereditary angioedema. Allergy Asthma Clin Immunol . 2010;6:24. PMID: ... chap 6. Read More Cirrhosis Complement Glomerulonephritis Hepatitis Hereditary angioedema Kidney transplant Lupus nephritis Systemic lupus erythematosus Ulcerative ...

  9. Comparative study of tramadol and piroxicam as analgesic for postoperative pain in patients operated for inguinal hernia and hydrocele

    Directory of Open Access Journals (Sweden)

    Ajay Kumar Shukla

    2016-04-01

    Conclusions: Piroxicam provides better and effective analgesia in acute post-operative pain along with the advantage of requiring lesser frequency of administration than tramadol. [Int J Basic Clin Pharmacol 2016; 5(2.000: 312-316

  10. Initial Pseudomonas aeruginosa infection in patients with cystic fibrosis: characteristics of eradicated and persistent isolates

    DEFF Research Database (Denmark)

    Tramper-Stranders, G. A.; van der Ent, C. K.; Molin, Søren;

    2012-01-01

    Clin Microbiol Infect 2012; 18: 567574 Abstract Despite intensive eradication therapy, some CF patients with early Pseudomonas aeruginosa infection rapidly develop a chronic infection. To elucidate factors associated with this persistence, bacterial characteristics of early P. aeruginosa isolates...

  11. Zincovit syrup ameliorates oxidative stress induced by carbon tetrachloride in rats

    Directory of Open Access Journals (Sweden)

    S. M. Satyam

    2015-06-01

    Conclusion: The present findings revealed that ZVT syrup may be useful in oxidative stress associated tissue damage as a nutritional food supplement. [Int J Basic Clin Pharmacol 2015; 4(3.000: 449-452

  12. Disease: H00348 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 34 McPhee SJ, Papadakis MA, Tierney LM (ed). Current Medical Diagnosis & Treatmen...matis infections. Clin Microbiol Infect 15:4-10 (2009) PMID:8993862 (description) Black CM Current methods o

  13. Disease: H00347 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available s: 000659 000439 McPhee SJ, Papadakis MA, Tierney LM (ed). Current Medical Diagno...lamydia trachomatis infections. Clin Microbiol Infect 15:4-10 (2009) PMID:8993862 (description) Black CM Current

  14. Laser Capture Microdissection Assisted Identification of Epithelial MicroRNA Expression Signatures for Prognosis of Stage I NSCLC

    Science.gov (United States)

    2014-12-01

    microRNA expression atlas based on small RNA library sequencing. Cell 129:1401-14, 2007 13. Sica A, Mantovani A: Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 122:787-95, 2012 18

  15. Comparative study of the efficacy and safety of olopatadine eyedrops and sodium cromoglycate in clinical practice: a prospective study

    Directory of Open Access Journals (Sweden)

    Scandashree K

    2016-10-01

    Conclusions: Olopatadine ophthalmic solution is better than sodium cromoglycate ophthalmic solution in reducing the ocular signs and symptoms in allergic conjunctivitis. [Int J Basic Clin Pharmacol 2016; 5(5.000: 1764-1769

  16. Faculty perception of medical council of India basic course workshop in medical education technologies as faculty development programme

    Directory of Open Access Journals (Sweden)

    Arvind Kumar Yadav

    2016-06-01

    Conclusions: BCW must be an integral part of the faculty development programme at institute level but its modules should be regularly updated time to time. [Int J Basic Clin Pharmacol 2016; 5(3.000: 846-849

  17. Changing physician behavior: interventions to improve prescription writing practices in a secondary level hospital in Delhi

    Directory of Open Access Journals (Sweden)

    Dipanweeta Routray

    2014-10-01

    Conclusion: Combining different intervention seems a noble approach to improve the prescription writing practices with respect to completeness and inclusion of generic drugs, drugs from EDL. [Int J Basic Clin Pharmacol 2014; 3(5.000: 840-844

  18. A study of effect of Nigella sativa oil in paracetamol induced hepatotoxicity in albino rats

    Directory of Open Access Journals (Sweden)

    Manik S. Ghadlinge

    2014-06-01

    Conclusion: This study demonstrated that NS oil has hepatoprotective effect. NS oil administration can prevent or reverse the hepatotoxicity induced by paracetamol. [Int J Basic Clin Pharmacol 2014; 3(3.000: 539-546

  19. Assessment of inhalation technique and predictors of incorrect performance among patients of chronic obstructive pulmonary disease and asthma

    Directory of Open Access Journals (Sweden)

    Tulika Jha

    2016-08-01

    Conclusions: Inhaler techniques improved with systematic training and there was a trend towards improvement in lung function, hence the clinical condition. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1598-1605

  20. Comparative evaluation of H1 receptor blocking activity and safety of newer H1antagonist mizolastine with loratadine and placebo: a randomized double blind three way crossover study

    Directory of Open Access Journals (Sweden)

    K. Swarnalatha

    2016-06-01

    Conclusions: Mizolastine has good antihistaminic activity than loratadine. Neither drug causes any psychomotor impairment or has anti-cholinergic action. [Int J Basic Clin Pharmacol 2016; 5(3.000: 661-675

  1. Performance of the orthopedic surgical services of the General University Hospital Gregorio Mara and ntilde; and oacute;n on the 11th of March terrorist outrage in Madrid

    Directory of Open Access Journals (Sweden)

    Francisco Chana Rodriguez

    2015-02-01

    Conclusions: The review of analyses of previous catastrophes, described by our colleagues in different studies, can be very useful inorder to avoid mistakes in the future. [Arch Clin Exp Surg 2015; 4(1.000: 14-20

  2. Evaluation of pharmacology teaching-learning methods in a government medical college

    Directory of Open Access Journals (Sweden)

    Aritra Ghosh

    2016-02-01

    Conclusions: This study helps in knowing students' opinion and preferences in curriculum to make it more interesting and aids to modify the undergraduate Pharmacology teaching pattern. [Int J Basic Clin Pharmacol 2016; 5(1.000: 126-130

  3. The Use of Patient-Specific Intra-Operative Guides for Total Knee Arthroplasty (TKA

    Directory of Open Access Journals (Sweden)

    Hendrik P. Delport

    2012-08-01

    Conclusions: We conclude that this novel technique hereby described has major benefits: less operative time and proper implant positioning, but more prospective studies are mandatory. [Arch Clin Exp Surg 2012; 1(4.000: 206-212

  4. Comparison of the acute effects of hemostatic agents on neural tissues in spine surgery: Histologic analysis in rat models

    Directory of Open Access Journals (Sweden)

    Gokhan Meric

    2016-03-01

    Conclusion: Both gelatin sponge and oxidized cellulose did not increase the cellular necrosis of neural tissues. However, oxidized cellulose may lead to an increased local inflammatory reaction. [Arch Clin Exp Surg 2016; 5(1.000: 21-26

  5. Antihypertensive and antiatherogenic effects of Tanopati a traditional recipe used for the treatment of high blood pressure

    Directory of Open Access Journals (Sweden)

    Amani Komenan Nazaire

    2016-10-01

    Conclusions: The results obtained confirm the antihypertensive effect of Tanopati and justify it traditionally use in treatment of high blood pressure. [Int J Basic Clin Pharmacol 2016; 5(5.000: 1903-1909

  6. Disease: H00356 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 8 (description, env_factor, comment) Collinet-Adler S, Ward HD Cryptosporidiosis: environmental, therapeutic, and preventive challeng...es. Eur J Clin Microbiol Infect Dis 29:927-35 (2010) PMID:12686887 (description, en

  7. Disease: H00084 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available bone marrow transplant. Annu Rev Med 54:29-52 (2003) PMID:15931364 (drug) Iwasaki T. Recent advances in the treatment of graft-versus-host disease. Clin Med Res 2:243-52 (2004) ...

  8. Disease: H00304 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available onjugate vaccine in the United Kingdom. Clin Ther 34:385-99 (2012) PMID:20980793 (drug) Fitzwater SP, Watt J...1990) PMID:22244051 (drug) Ladhani SN Two decades of experience with the Haemophilus influenzae serotype b c

  9. Klebsiella Species Infections in the Department of the Navy [DoN] and Department of Defense [DoD]: Annual Report 2014

    Science.gov (United States)

    2016-03-14

    Klebsiella pneumoniae carbapenemase ( KPC ), commonly identified in K. pneumoniae isolates. 3 Furthermore, bacteria with carbapenem-resistant genes typically...DS. Treatment of Klebsiella pneumoniae carbapenemase ( KPC ) infections: a review of published case series and case reports. Ann Clin Microbiol

  10. Disease: H00088 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00088 Common variable immunodeficiency (CVID), including the following four diseases...SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin ..., Wedgwood J. Primary immunodeficiency diseases: an update from the International Union of Immunological Soc

  11. The protective effect of Withania somnifera against oxidative damage caused by ethanol in the testes of adult male rats

    Directory of Open Access Journals (Sweden)

    Divya Bhargavan

    2015-12-01

    Conclusion: These observations suggest that the antioxidant property of WS might have contributed for its ability to ameliorate the testicular toxicity caused by alcohol. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1104-1108

  12. Pattern of use of antibiotics in hospitalized patients in the medicine department of a tertiary care hospital

    Directory of Open Access Journals (Sweden)

    Muniza Bai

    2015-10-01

    Conclusion: Ceftriaxone, doxycycline, and metronidazole are commonly used antibiotics and significant proportion of the cost of drugs is spent for antimicrobials in a medicine unit. [Int J Basic Clin Pharmacol 2015; 4(5.000: 888-894

  13. Disease: H01178 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available . (secondary/wound myiasis) Turpentine oil (Oral myaisis) Gatifloxacin (Ophthalmo...gadge AP, Chande MS, Bhalerao S, Tamgadge S Oral myiasis. Contemp Clin Dent 1:275-6 (2010) PMID:22124072 (de

  14. Interaction of two memory enhancing herbal drugs Memory Plus and Mentat with diazepam and phenytoin sodium in mice

    Directory of Open Access Journals (Sweden)

    Neera R. Gupta

    2015-04-01

    Conclusion: Subchronic administration of MP and Mentat shows significant interaction with diazepam and PS. Further human studies are warranted to confirm these findings. [Int J Basic Clin Pharmacol 2015; 4(2.000: 203-207

  15. Evaluation of effect of alcoholic extract of Tinospora cordifolia on learning and memory in alprazolam induced amnesia in albino mice

    Directory of Open Access Journals (Sweden)

    Jyothi C. H.

    2016-10-01

    Conclusions: Tinospora cordifolia, Indian medicinal plant useful for treatment of various ailments can also be a useful alternative for treating dementia and associated diseases like alzheimer's disease. [Int J Basic Clin Pharmacol 2016; 5(5.000: 2159-2163

  16. Assessment of Curcuma longa linn. on learning and memory in rats

    Directory of Open Access Journals (Sweden)

    K. Lohit

    2015-12-01

    Conclusion: C. longa linn. may be useful in enhancing learning. Further dose ranging preclinical studies are required to evaluate the efficacy of curcumin on memory. [Int J Basic Clin Pharmacol 2015; 4(6.000: 1086-1090

  17. To evaluate and compare the hypoglycemic, antioxidant and hypolipidemic effect of lycopene with atorvastatin in hyperlipidemic New Zealand white rabbits

    Directory of Open Access Journals (Sweden)

    Sarita Mulkalwar

    2015-02-01

    Conclusion: Findings suggest that lycopene may have considerable therapeutic benefit as an antioxidant and hypolipidemic agent, but may not be effective as a hypoglycemic agent. [Int J Basic Clin Pharmacol 2015; 4(1.000: 148-152

  18. Experimental evaluation of anti-hyperglycemic and hypolipidemic effects of stevia rebaudiana, Anacardium occidentale on wistar rats

    Directory of Open Access Journals (Sweden)

    Brijesh K.

    2016-12-01

    Conclusions: The present experimental study is preliminary one elaborate study with larger sample size is required to come up with a more significant result. [Int J Basic Clin Pharmacol 2016; 5(6.000: 2463-2467

  19. Pharmacokinetics and clinical evaluations of gentamicin-induced nephrotoxicity in puppies

    Directory of Open Access Journals (Sweden)

    Fidelis A. Gberindyer

    2015-08-01

    Conclusion: These suggest the risk of nephrotoxicity following treatment with gentamicin beyond 5 consecutive days irrespective of the dosing interval in puppies. [Int J Basic Clin Pharmacol 2015; 4(4.000: 691-696

  20. Effect of Lagenaria siceraria fruit extract (Bottle gourd on hepatotoxicity induced by antitubercular drugs in albino rats

    Directory of Open Access Journals (Sweden)

    Satyajeet K. Funde

    2013-12-01

    Conclusion: Ethanolic extract of Lagenaria siceraria fruit possesses significant hepatoprotective and antioxidant activity in antitubercular drugs induced hepatotoxicity. [Int J Basic Clin Pharmacol 2013; 2(6.000: 728-734

  1. Disease: H00485 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00485 Robinow syndrome Robinow syndrome is characterized by distinctive craniofacial...hn MT, Cunningham ML, Petryk A, Lohr JL Craniofacial and intraoral phenotype of Robinow syndrome forms. Clin Genet 80:15-24 (2011) ...

  2. Evaluation of analgesic activity of Aegle marmelos steam bark in experimental animals

    Directory of Open Access Journals (Sweden)

    Sarang Gajanan Ghodki

    2016-06-01

    Conclusions: AMSBAE has analgesic activity. The analgesic activity of AMSBAE was comparable to that of tramadol and Aspirin. Hence, AMSBAE could be a possible alternative to NSAIDs. [Int J Basic Clin Pharmacol 2016; 5(3.000: 1081-1086

  3. Evaluation of efficacy and tolerability of eperisone and thiocolchicoside in treatment of low back pain associated with muscle spasm: An open label, prospective, randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Syed H. Maaz

    2016-12-01

    Conclusions: Eperisone is an effective muscle relaxant with equivalent efficacy compared to Thiocolchicoside, and has a better tolerability in treatment of low back pain with muscle spasm. [Int J Basic Clin Pharmacol 2016; 5(6.000: 2669-2674

  4. Comparative study of problem based learning versus structured group discussion in teaching pharmacology

    Directory of Open Access Journals (Sweden)

    Laveesh M. R.

    2016-10-01

    Conclusions: PBL and SGD are effective small group methods for teaching undergraduate medical students. However learning outcome with PBL is better than SGD. [Int J Basic Clin Pharmacol 2016; 5(5.000: 1877-1880

  5. Perceptions and suggestions of second year medical professional students of deemed health university about their teaching and learning process in pharmacology: an analytical study

    Directory of Open Access Journals (Sweden)

    Nagapati Prabhakar Bhat

    2016-06-01

    Conclusions: This study has helped us in knowing the student preferences regarding pharmacology teaching and its outcomes would be helpful in modifying undergraduate pharmacology teaching pattern. [Int J Basic Clin Pharmacol 2016; 5(3.000: 763-768

  6. Disease: H00373 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D:16288402 (description, drug) Nalca A, Rimoin AW, Bavari S, Whitehouse CA Reemergence of monkeypox: preva...lence, diagnostics, and countermeasures. Clin Infect Dis 41:1765-71 (2005) PMID:176

  7. Efficacy and safety of ivabradine as an add-on to atenolol in patients with chronic stable ischemic heart disease

    Directory of Open Access Journals (Sweden)

    Elavarasi Pichai

    2016-12-01

    Conclusions: Ivabradine is safe and effective in preventing and treating further anginal attacks in patients with chronic stable ischemic heart disease already on atenolol therapy. [Int J Basic Clin Pharmacol 2016; 5(6.000: 2546-2551

  8. Disease: H01057 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available gon BL Gnathostomiasis: a review of a previously localized zoonosis now crossing ...actor) Rusnak JM, Lucey DR Clinical gnathostomiasis: case report and review of the English-language literature. Clin Infect Dis 16:33-50 (1993) ...

  9. Disease: H01049 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available imi LA, Yawetz S, Lasker BA, Bolcen SJ, Brown JM, Marty FM Gordonia bronchialis bacteremia and pleural infection: case report and rev...iew of the literature. J Clin Microbiol 49:1662-6 (2011) ...

  10. Comparative study to evaluate the anti-diabetic activity of commercially available extract of Tinospora cordifolia and Phyllanthus emblica in streptozocin induced diabetic rat

    Directory of Open Access Journals (Sweden)

    Nishant Pathak

    2016-08-01

    Conclusions: Commercially available extract of Tinospora cordifolia and Phyllanthus emblica have significant anti-diabetic activity in streptozocin induced diabetic rats. [Int J Basic Clin Pharmacol 2016; 5(4.000: 1641-1646

  11. Use of an iron-overexchanged clinoptilolite for the removal of Cu2+ ions from heavily contaminated drinking water samples.

    Science.gov (United States)

    Doula, M K; Dimirkou, A

    2008-03-01

    Clinoptilolite, a natural zeolite, was used for the synthesis of a high surface area clinoptilolite-iron oxide system, in order to be used for the removal of Cu2+ ions from drinking water samples. The solid system was obtained by adding natural clinoptilolite in an iron nitrate solution under strongly basic conditions. The Clin-Fe system has specific surface area equal to 151 m2 g(-1) and is fully iron exchanged (Fe/Al=1.23). Batch adsorption experiments were carried out to determine the effectiveness of the Clin and the Clin-Fe system in removal of copper from drinking water. Adsorption experiments were conducted by mixing 1.00 g of each of the substrates with certain volume of water samples contaminated with 10 different Cu concentrations (from 3.15x10(-5) to 315x10(-2) M or from 2.00 to 2000 ppm Cu). For our experimental conditions, the maximum adsorbed Cu amount on Clin was 13.6 mg g(-1) whereas on the Clin-Fe system was 37.5 mg g(-1). The main factors that contribute to different adsorption capacities of the two solids are due to new surface species and negative charge of the Clin-Fe system. In addition, the release of counterbalanced ions (i.e. Ca2+, Mg2+, Na+ and K+) was examined, as well as the dissolution of framework Si and Al. It was found that for the most of the samples the Clin-Fe system releases lower concentrations of Ca, Mg and Na and higher concentrations of K than Clin, while the dissolution of Si/Al was limited. Changes in the composition of water samples, as well as in their pH and conductivities values were reported and explained.

  12. Removal of Mn2+ ions from drinking water by using Clinoptilolite and a Clinoptilolite-Fe oxide system.

    Science.gov (United States)

    Doula, Maria K

    2006-10-01

    Clinoptilolite, a natural zeolite, was used for the synthesis of a high surface area Clinoptilolite-Iron oxide system, in order to be used for the removal of Mn2+ ions from drinking water samples. The new system was obtained by adding natural clinoptilolite in an iron nitrate solution under strongly basic conditions. The Clin-Fe system has specific surface area equal to 151.0 m2/g and is fully iron exchanged (Fe/Al = 1.23). Batch adsorption experiments were carried out to determine the effectiveness of the Clin and the Clin-Fe system in removal of manganese from drinking water. Adsorption experiments were conducted by mixing 1.00 g of each of the substrates with certain volume of water samples contaminated with 10 different Mn concentrations (from 3.64 x 10(-6) to 1.82 x 10(-2) M or from 0.2 to 1000 ppm). For the present experimental conditions, the Mn adsorption capacity of Clin was 7.69 mg/g, whereas, of Clin-Fe system was 27.12 mg/g. The main factors that contribute to difference adsorption capacity of the two solids are due to new surface species and negative charge of Clin-Fe system. In addition, the release of counterbalanced ions (i.e., Ca2+, Mg2+, Na+ and K+) was examined as well as the dissolution of framework Si and Al. It was found that for the most of the samples the Clin-Fe system releases lower concentrations of Ca, Mg and Na and higher concentrations of K than Clin, while the dissolution of Si/Al was limited. Changes in the composition of water samples as well as in their pH and conductivities values were reported and explained.

  13. Modulation of Polymorphonuclear Neutrophil Response to N-formyl-l-methionyl-l-leucyl-l-phenylalanine

    Science.gov (United States)

    1988-11-10

    to the scapular crests. The skin was closed with 4/0 chromic gut placed in a continuous subcuticular suture pattern and bandaged. These procedures...Clin. Immun. and Immunopath., 15:525, 1980. 16. Gray, G.D., Ohlmann, G.M., Morton. D.R. and Schaaub, R.G., Feline Polymorphonuclear Leukocytes Respond...Mature Human Neutrophil and Eosinophil Function, Surface Receptor Expression and Survival. J. Clin. Invest., 78:1220, 1986. Gasson, J .C., Weisbart

  14. The birth of oligodendrocytes in the anatomical and neuropathological literature: the seminal contribution of Pio del Rio-Hortega. 1921.

    Science.gov (United States)

    Lassmann, Hans

    2012-01-01

    Comment on: del Río-Hortega P. Glia with very few processes (oligodendroglia). Clin Neuropathol. 2012; 31: 440-459, originally published in Archivos de Neurobiología. 1921; 2: 16-43 and del Río-Hortega P. Are the glia with very few processes homologous with Schwann cells? Clin Neuropathol. 2012; 31: 460-462, originally published in Bol de la Soc Esp de Biol. 1922; X: 25-28.

  15. The discovery of oligodendroglia cells by Rio-Hortega: his original articles. 1921.

    Science.gov (United States)

    Iglesias-Rozas, José R; Garrosa, Manuel

    2012-01-01

    Comment on: del Río-Hortega P. Glia with very few processes (oligodendroglia). Clin Neuropathol. 2012; 31: 440-459, originally published in Archivos de Neurobiología. 1921; 2: 16-43 and del Río-Hortega P. Are the glia with very few processes homologous with Schwann cells? Clin Neuropathol. 2012; 31: 460-462, originally published in Bol de la Soc Esp de Biol. 1922; X: 25-28.

  16. AR Alternative Splicing and Prostate Cancer Progression

    Science.gov (United States)

    2012-07-01

    established from a transplantable primary CWR22 tumor. Clin Cancer Res 2008;14:6062–72. 24. Dehm SM, Tindall DJ. Ligand-independent androgen receptor...diverse tissues including heart, muscle, uterus , prostate, lung, and breast, with no apparent expression in brain. However, these RT-PCR experi- ments...tumorigenic human prostate cancer cell line established from a transplantable primary CWR22 tumor. Clin Cancer Res 2008; 14: 6062 - 6072. 42 Gregory CW

  17. Low Ultraviolet B and Increased Risk of Brain Cancer: An Ecological Study of 175 Countries

    Science.gov (United States)

    2009-07-01

    Mean Author Year Journal Location 25(OH)D ng/ml Mazess et al. 1985 Am J Clin Nutr Alaska, USA 16.6 Oliveri et al. 1990 Medicina Buenos Aires...Clin Nutr USA 32.9 Rucker et al. 2002 Cmaj Calgary, Canada 23.8 Tangpricha et al. 2002 Am J Med USA 29.1 Fassi et al. 2003 Medicina Buenos Aires

  18. Characterization and Targeting of the Aldehyde Dehydrogenase Subpopulation in Ovarian Cancer

    Science.gov (United States)

    2012-07-01

    in androgen-independent prostate cancer. Clin Cancer Res 2008;14:5769–77. Putative Ovarian Cancer Stem Cells and Recurrence www.aacrjournals.org Clin... cyclooxygenase -2 in cervical, endometrial, and ovarian malignancies. Am J Obstet Gynecol 188(5):1174-1176, 2003. 9. Landen CN Jr, Younger NO...Obstetricians and Gynecologists, 2000. 7. Landen CN, Mathur SP, Richardson MS, Creasman WT. Expression of cyclooxygenase -2 in cervical

  19. Activity of Topical Antimicrobial Agents Against Multidrug-Resistant Bacteria Recovered from Burn Patients

    Science.gov (United States)

    2010-01-01

    BAC MUP B/N/P SN SS MA H Susc Clin Ery Gent Levo Lin Mox Q/D Rif Tet T/S Vanc 1 >256 1 64 32 8 32 1024 5 9 150 9 12 22 34 22 R R S R S R S S S S S 1...Clin = clindamycin; Ery = erythromycin; Gent = gentamicin; Levo = levofloxacin; Lin = linezolid; Mox = moxifloxacin; Q/D = quinupristin/dalfopristin

  20. Clinical Infectious Outcomes Associated with Biofilm-related Infections: a Retrospective Chart Review

    Science.gov (United States)

    2015-06-07

    analysis of potential clinical risk factors and infectious outcomes of a large data set is an important addition to the understand- ing of this...in adults. Clin Infect Dis. 2005;40(5):643–54. 11. Mermel LA, Allon M, Bouza E, Craven DE, Flynn P, O’Grady NP, et al. Clinical practice guidelines ...associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clin

  1. Framework for automatic information extraction from research papers on nanocrystal devices

    Directory of Open Access Journals (Sweden)

    Thaer M. Dieb

    2015-09-01

    Full Text Available To support nanocrystal device development, we have been working on a computational framework to utilize information in research papers on nanocrystal devices. We developed an annotated corpus called “ NaDev” (Nanocrystal Device Development for this purpose. We also proposed an automatic information extraction system called “NaDevEx” (Nanocrystal Device Automatic Information Extraction Framework. NaDevEx aims at extracting information from research papers on nanocrystal devices using the NaDev corpus and machine-learning techniques. However, the characteristics of NaDevEx were not examined in detail. In this paper, we conduct system evaluation experiments for NaDevEx using the NaDev corpus. We discuss three main issues: system performance, compared with human annotators; the effect of paper type (synthesis or characterization on system performance; and the effects of domain knowledge features (e.g., a chemical named entity recognition system and list of names of physical quantities on system performance. We found that overall system performance was 89% in precision and 69% in recall. If we consider identification of terms that intersect with correct terms for the same information category as the correct identification, i.e., loose agreement (in many cases, we can find that appropriate head nouns such as temperature or pressure loosely match between two terms, the overall performance is 95% in precision and 74% in recall. The system performance is almost comparable with results of human annotators for information categories with rich domain knowledge information (source material. However, for other information categories, given the relatively large number of terms that exist only in one paper, recall of individual information categories is not high (39–73%; however, precision is better (75–97%. The average performance for synthesis papers is better than that for characterization papers because of the lack of training examples for

  2. Cloud Computing Strategy

    Science.gov (United States)

    2012-07-01

    delivery and integrated  DevOps .  This test and development cloud  environment will enable applications and services to run in a distributed environment...reducing  time to deliver content to clients.        This cloud development and test environment will:  " DevOps " is an emerging set of principles

  3. A Study on the Software Quality Assurance Plan

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Tae [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    2006-07-01

    On 25 August 2006, the CMMI V1.2 (Capability Maturity Model Integration Version 1.2) was released with the new title CMMI-DEV (CMMI for Development) which supersedes the CMMI-SE/SW (CMMI for systems engineering and software engineering) V1.1. This study discusses the application of IEEE Std 730-2002, IEEE Standard for Software Quality Assurance Plans, for the implementation of the Process and Product Quality Assurance (PPQA) process area (PA) of the CMMI-DEV.

  4. Expression and characterization of the UL31 protein from duck enteritis virus

    Directory of Open Access Journals (Sweden)

    Zhu Dekang

    2009-02-01

    Full Text Available Abstract Background Previous studies indicate that the UL31 protein and its homology play similar roles in nuclear egress of all herpesviruses. However, there is no report on the UL31 gene product of DEV. In this study, we expressed and presented the basic properties of the DEV UL31 product. Results The entire ORF of the UL31 was cloned into pET 32a (+ prokaryotic expression vector. Escherichia coli BL21(DE3 competent cells were transformed with the construct followed by the induction of protein expression by the addition of IPTG. Band corresponding to the predicted sizes (55 kDa was produced on the SDS-PAGE. Over expressed 6×His-UL31 fusion protein was purified by nickel affinity chromatography. The DEV UL31 gene product has been identified by using a rabbit polyclonal antiserum raised against the purified protein. A protein of approximate 35 kDa that reacted with the antiserum was detected in immunoblots of DEV-infected cellular lysates, suggesting that the 35 kDa protein was the primary translation product of the UL31 gene. RT-PCR analyses revealed that the UL31 gene was transcribed most abundantly during the late phase of replication. Subsequently, Immunofluorescence analysis revealed that the protein was widespread speckled structures in the nuclei of infected cells. Western blotting of purified virion preparations showed that UL31 was a component of intracellular virions but was absent from mature extracellular virions. Finally, an Immunofluorescence assay was established to study the distribution of the UL31 antigen in tissues of artificially DEV infected ducks. The results showed that the UL31 antigen was primarily located in the cells of digestive organs and immunological organs. Conclusion In this work, we present the basic properties of the DEV UL31 product. The results indicate that DEV UL31 shares many similarities with its HSV or PRV homolog UL31 and suggest that functional cross-complementation is possible between members of the

  5. Fabryq: Using Phones as Smart Proxies to Control Wearable Devices from the Web

    Science.gov (United States)

    2014-06-12

    drivers for a partic- ular phone, but this is difficult. The principal difference is fabryq’s focus on supporting custom peripheral devices. IoT ...Installs My HFHH Install My Cheap HR My SmartCup HFHH SmartCup HR Monitor Device Service Char Virt. Dev App Type Instance Legend Install My Cheap HR My...Borriello, G. Open data kit sensors: Mobile data collection with wired and wireless sensors. In Proceedings of the ACM DEV , ACM (2012), 9:19:10. 7

  6. Keeping Special Forces Special: Regional Proficiency in Special Forces

    Science.gov (United States)

    2011-12-01

    than one month IOT allow Soldiers to listen to the language, conduct travel/recon etc. —Special Forces Soldier294 Immersion is the third method by...incentive lower. Conversely, a person with a lower interest in regional proficiency would rate the incentive higher. Variable Mean Std Dev Regional...Variable Mean Std Dev Regional Proficiency Interest 6.29 .99 Command Environment Value 4.41 1.62 PDSI 2.54 1.60 Promotion 2.92 1.62 153

  7. Joint Precision Approach and Landing System Increment 1A (JPALS Inc 1A)

    Science.gov (United States)

    2013-12-01

    Defense Acquisition Management Information Retrieval Dev Est - Development Estimate DoD - Department of Defense DSN - Defense Switched Network Econ...March 19, 2014. JPALS Inc 1A December 2013 SAR April 16, 2014 17:17:18 UNCLASSIFIED 7 Schedule Milestones SAR Baseline Dev Est... IOT &E JAN 2014 JAN 2014 JUL 2014 TBD 1 (Ch-2) IOC DEC 2014 DEC 2014 JUN 2015 TBD 1 (Ch-2) FRP JUN 2015 JUN 2015 DEC 2015 TBD 1 (Ch-2) 1APB Breach Change

  8. SMC Systems Engineering: Specialty Engineering Disciplines Framework and Descriptions. Volume 2

    Science.gov (United States)

    2011-10-03

    Olher FONms lr!l)actYig T&E I - Implement DT&E; Prepare OT&E; Perform T&E Evals I -SUili>O’I Design Analyses, SE Activities, ILS I - Dev T&E...Engineer supports Developmental Test and Evaluation (DT &E), Initial Operational Test and Evaluation ( IOT &E), Operational Test and Evaluation (OT&E...Analyses 1- Dev SNi Eng Products e.g. Assessmenls, Rills, Certs 1- ID & Manage Resources: Tools, Equip, Skills Assess Contractors’ Compian<:e to SIW Eng

  9. tITering : empresa de gestió massiva de servidors amb Puppet

    OpenAIRE

    Urpinas Colet, Lluis

    2016-01-01

    Gestió masiva servidors virtuals en una empresa de nova implantació This project aims to analyze the economic savings that a services company with DevOps philosophy would gain by firstly transferring physical server to virtual ones, and then manage these systems with meta- management tools like Puppet. Analyze not only the economic value of these changes in the DevOp process but also the time thah would take to implement it, the needs in terms of human resources to carry it out and possibl...

  10. Bacteriological quality of creeks and marine water bodies in North Goa: Ecosystem upkeep perspectives for tourism-related activities

    Digital Repository Service at National Institute of Oceanography (India)

    Ramaiah, N.; Sadhasivan, A.; Iyer, S.R.

    stream_size 33716 stream_content_type text/plain stream_name Coastal_Tour_Environ_Sustain_Local_Dev_2003_211.pdf.txt stream_source_info Coastal_Tour_Environ_Sustain_Local_Dev_2003_211.pdf.txt Content-Encoding UTF-8 Content-Type... are very rapid (Pickett 1991) and consistent, as compared with those of higher forms of biota. These responses and bacterial types are useful for monitoring environmental quality. Through careful planning, choice, and analysis of relevant bacteriological...

  11. Combat Service Support Mission Area Materiel Plan (CSS MAMP) User’s Manual.

    Science.gov (United States)

    1985-09-30

    tb. vb, u91_tb. vb.u92-tb. vb; print fS5_dcv,vb.#96_dcv. vb. 97_dev, vb. #98_dcv, vb, 3 #8fI9_dcv. vb, #90_dcv. vb. #91 _dev~vb, #92_dcv, vbj U print...break - 31 Iit wkpkg_ titloE32.323 - then lot break - 32 if wkpkg~titloE33,333 - " then lot break - 33 print whpkg~titl@El, break]. column 64. vbj ~f fIf

  12. Documentation of the Tonge-Ramesh Material Model for Release 2015-06-05-152756

    Science.gov (United States)

    2015-10-01

    Coefficient of friction for clean self contact. Used in the micromechanics calculation. 3 28) FlawAngle: Radians—Angle between the maximum compressive...based on a wing-cracking mechanism (Tonge 2014, eqs. 4.57 and 4.58). It depends on the crack-face coefficient of friction (FlawFriction), applied load...current state of the material (Simo and Hughes 2000, sec . 2.7.4). The plastic flow direction ism = (n+ ζAÎ)/ √ 1 + ζ2A2. Here n = τ dev/||τ dev||, Î

  13. Depression and Anxiety in Iranian Mothers of Children with Epilepsy

    Directory of Open Access Journals (Sweden)

    Atefeh SOLTANIFAR

    2012-03-01

    JS, Lisonkova S. Periodprevalence of epilepsy in children in BC: a population-basedstudy. Can J Neurol Sci 2009 Jan;36(1:36-41.3. Otero S. Psychopathology and psychological adjustmentin children and adolescents with epilepsy. World J Pediatr2009 Feb;5(1:12-7.4. Rodenburg HR, Stams GJJM, Meijer AM, Aldenkamp AP,Dekovic´ M. Psychopathology in children with epilepsy:a metaanalysis. J Pediatr Psychol 2005 Sep;30(6:453-68.Epub 2005 Mar 3.5. Rodenburg R, Meijer AM, Dekovic M, AldenkampAP. Family factors and psychopathology in childrenwith epilepsy: a literature review. Epilepsy Behav 2005Jun;6(4:488-503.6. Lovejoy M, Graczyk PA, O_Hare E, Neuman G. Maternaldepression and parenting behavior: a meta-analytic reviewClin Psychol Rev 2000;20:561-92.7. Shore CP, Buelow JM, Austin JK, Johnson CS.Continuing psychosocial care needs in children with newonsetepilepsy and their parents. J Neurosci Nurs 2009Oct;41(5:244-50.8. Pianta RC, Lothman DJ. Predicting behavior problemsin children with epilepsy: child factors, disease factors,family stress, and child-mother interaction. Child Dev1994 Oct;65(5:1415-28.9. Dunn DW, Austin JK, Huster GA. Symptoms ofdepression in adolescents with epilepsy. J Am Acad ChildAdolesc Psychiatr 1999;38:1133-8.10. Shore CP, Austin JK, Huster GA, Dunn DW. Identifyingrisk factors for maternal depression in families ofadolescents with epilepsy. J Specialists Pediatr Nurs2002;7:71-80.11. Yongli, Cheng-Ye ji, Jiong Qin, Zhi-Xiang Zhang.Parental anxiety and quality of Life of epileptic children.Biomed Environ Sci 2008 Jun;21(3:228-32.12. Williams J, Steel C, Sharp GB, DelosReyes E, PhillipsT, Bates S, et al. Parental anxiety and quality of life inchildren with epilepsy. Epilepsy Behav 2003;4:483-6.13. Lv R, Wu L, Jin L, Lu Q, Wang M, Qu Y, Liu H. Depression,anxiety and quality of life in parents of children withepilepsy. Acta Neurol Scand 2009 Nov;120(5:335-41.14. Baki O, Erdogan A, Kantarci O, Akisik G, KayaalpL, Yalcinkaya C. Anxiety and depression in

  14. Brief Report: Preliminary Evaluation of the Theory of Mind Inventory and Its Relationship to Measures of Social Skills

    Science.gov (United States)

    Lerner, Matthew D.; Hutchins, Tiffany L.; Prelock, Patricia A.

    2011-01-01

    This study presents updated information on a parent-report measure of Theory of Mind (ToM), formerly called the Perception of Children's Theory of Mind Measure (Hutchins et al., "J Autism Dev Disord" 38:143-155, 2008), renamed the Theory of Mind Inventory (ToMI), for use with parents of children with autism spectrum disorder (ASD). This study…

  15. Getting started with Hazelcast

    CERN Document Server

    Johns, Mat

    2015-01-01

    This book is a great introduction for Java developers, software architects, or DevOps looking to enable scalable and agile data within their applications. Providing in-memory object storage, cluster-wide state and messaging, or even scalable task execution, Hazelcast helps solve a number of issues that have troubled technologists for years.

  16. Anterior fontanelle pressure monitoring in infants

    NARCIS (Netherlands)

    W.C.G. Overweg-Plandsoen

    1990-01-01

    textabstractThe objectives of this study were 1 To evaluate whether the R TT could be used as a 'fontanometer'. The literature on non-invasive ICP measurement techniques used in infants and children was studied to avoid problems already encountered by others. Subsequently, a special R TT holding dev

  17. Disease: H00112 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00112 Paratyphoid fever Paratyphoid fever is a systemic febrile illness endemic in developing...eloping countries where sanitation is lacking and the access to clean water is redu... countries that is a similar to typhoid fever but gives a milder infection. The disease mainly affects those living in dev

  18. Reference: 788 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available programmed cell death of the endothelium in developing seeds. 8 2205-20 18676877 2008 Aug The Plant cell And...eloping seeds. PDI5 interacts with three different Cys proteases in yeast two-hybri...cations and functions. We demonstrate that PDI5 is expressed in endothelial cells about to undergo programmed cell death (PCD) in dev

  19. Experiment list: SRX050596 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available late embryonic stage 27506893,95.6,39.6,0 GSM694121: MCM S2 July 2010 extraction2 seq1 aliquote 1 source_name=MCM S2 July 2010 extrac...tion2_seq1 channel_1 || cell line=S2-DRSC || tissue=embryo-derived cell-line || dev

  20. Student Perceptions of Effective Instruction and the Development of Critical Thinking: A Replication and Extension

    Science.gov (United States)

    Loes, Chad N.; Salisbury, Mark H.; Pascarella, Ernest T.

    2015-01-01

    This study utilized data from the Wabash National Study of Liberal Arts Education to test the robustness of research conducted by Pascarella et al. ("J Coll Stud Dev" 37:7-19, 1996) that explored the relationship between student perceptions of exposure to organized and clear instruction and growth in critical thinking skills among…

  1. Assessment of Radar Detection Performance Using Design of Experiments: A Case Study

    Science.gov (United States)

    2013-01-01

    Valor Experimental Design Approach Step 4 – Select a Design Design Runs Center Points Power (%) (ME) VIF DOF Std. Error Model LOF PE (FDS...Power (1 std. dev.) at  = 0.05 9 Legend: ME – main effects 2FI – two factor interactions DOF – degrees-of-freedom VIF – variance

  2. Perceived Social Competence and Loneliness among Young Children with ASD: Child, Parent and Teacher Reports

    Science.gov (United States)

    Zeedyk, Sasha M.; Cohen, Shana R.; Eisenhower, Abbey; Blacher, Jan

    2016-01-01

    Perceived loneliness and social competence were assessed for 127 children with ASD without comorbid ID, 4-7 years old, through child self-report. Using an abbreviated version of the "Loneliness and Social Dissatisfaction Questionnaire" (LSDQ; Cassidy and Asher in "Child Dev" 63:250-365, 1992), the majority of children reported…

  3. Measuring Meaningful Outcomes in Consequential Contexts: Searching for a Happy Medium in Educational Technology Research (Phase II)

    Science.gov (United States)

    Ross, Steven M.; Morrison, Jennifer R.

    2014-01-01

    In a paper published 25 years ago, Ross and Morrison ("Educ Technol Res Dev" 37(1):19-33, 1989) called for a "happy medium" in educational technology research, to be achieved by balancing high rigor of studies (internal validity) with relevance to real-world applications (external validity). In this paper, we argue that,…

  4. Riik vajab pead / Mark Soosaar

    Index Scriptorium Estoniae

    Soosaar, Mark, 1946-

    2006-01-01

    Autori sõnul on president ainuke persoon riigis, kes on pädev esindama Eestit kohtumistel teiste riigipeadega. Samas loodab ta, et linna- ja vallavolinikud lähtuvad valijameeste valimisel peaeesmärgist - saada Eestile parim võimalik president

  5. Linking theories of change and observed reality: the Shea value chain partnership case in Burkina

    NARCIS (Netherlands)

    Drost, S.; Wijk, van J.; Vellema, S.

    2012-01-01

    This case study found out how a public-private partnership in Burkina Faso helped female shea nut producers to link up with the cosmetic industry. Empirical data collected from October-December 2011 revealed that the shea value chain partnership between a international shea processing company, a dev

  6. Bayesian Sparse Partial Least Squares

    NARCIS (Netherlands)

    Vidaurre, D.; Gerven, M.A.J. van; Bielza, C.; Larrañaga, P.; Heskes, T.M.

    2013-01-01

    Partial least squares (PLS) is a class of methods that makes use of a set of latent or unobserved variables to model the relation between (typically) two sets of input and output variables, respectively. Several flavors, depending on how the latent variables or components are computed, have been dev

  7. Proceedings of the Annual Military Librarians’ Workshop (21st): Resource Sharing, 27-29 September 1977

    Science.gov (United States)

    1977-09-29

    Library Fort Devens, MA 01433 Betty H. Fogler AV: 266-2031 Reference Librarian (Govt Docs Chief) US Air Force Academy Library SEleanor A. Driscoll USAF...Carlisle Barracks, PA 17013 Scott AFE, IL 62225 AV- 242-4442 AV: 638-3228SA 6George Vrooman Dodie C. Thomas Lihrarian Branc Offie, LndonBo 3 DevLopmerint

  8. Knockout AR in Prostate

    Science.gov (United States)

    2007-10-01

    Communicated by Henry Lardy, University of Wisconsin-Madison, Madison, WI, June 15, 2007 (received for review March 22, 2007)Accepted on May 17, 2007...Cardiff RD, Cunha GR, et al. (1999) Genes Dev 13:966–977. 19. Kim MJ, Bhatia-Gaur R, Banach- Petrosky WA, Desai N, Wang Y, Hayward SW, Cunha GR, Cardiff

  9. Testing predictive control of movement in children with developmental coordination disorder using converging operations

    NARCIS (Netherlands)

    Adams, I.L.J.; Lust, J.M.; Wilson, P.H.; Steenbergen, B.

    2017-01-01

    Recent systematic reviews (Wilson et al., 2013, Dev. Med. Child Neurol., 55, 217; Adams et al., 2014, Neurosci. Biobehav. Rev., 47C, 225) suggest that a common underlying problem in developmental coordination disorder (DCD) is the internal modelling deficit. The study presented here is

  10. Electroacoustic Music Is a "Subversion" to the Form of Traditional Music——An Idea From "Etudes Metro"—the Work of Pierre

    Institute of Scientific and Technical Information of China (English)

    Muyan Li

    2011-01-01

    We have studied"Metro Etudes"—the work of Pierre Schaeffer in this paper, and exploited the proposal of the concept of "concrete music". We discuss the basic concepts and characteristics of the current electroacoustic musics profoundly, analysis their dev

  11. Literatuuronderzoek voertuigkering H4-niveau : een literatuurstudie naar voertuigkeringen beproefd op H4-niveau volgens prEN 1317-1 en prEN 1317-2. In opdracht van Bouwdienst Rijkswaterstaat, Apeldoorn.

    NARCIS (Netherlands)

    Pol, W.H.M. van de

    1997-01-01

    Not many full-scale tests at the H4 level have yet been carried out according to the first and second standards of the prEN 1317. For this reason, only a few H4 tests are mentioned in the literature. Full-scale tests conducted with heavy vehicles are also mentioned in the literature. These tests dev

  12. Accelerated Tumor Cell Death by Anglogenic Modifiers

    Science.gov (United States)

    2005-08-01

    1164, 1994 442--447,1987 36. Brooks PC, Clark RAF, Cheresh DA: Requirement of vas- 20. Pepper MS: Manipulating angiogensis: from basic science cular...tol 22:1-10. stasis in transgenic mice. Genes Dev 9:945-955. 518 Cunha, G.R. and Chung, L.W. (1981) Stromal-epithelial interac- Corty, EW, Ferguson

  13. Viral Vectors for Use in the Development of Biodefense Vaccines

    Science.gov (United States)

    2005-06-17

    in 1954 when scientists were trying to establish cells lines derived from tonsil and adenoidal tissues and has recently been utilized extensively as a...Ferguson, D.M. Stone , J. Meredith, J.W. Almond, P.D. Minor, Live-attenuated strains of improved genetic stability, Dev. Biol. (Basel) 105 (2001) 179–187

  14. The Autism Diagnostic Observation Schedule--Toddler Module: A New Module of a Standardized Diagnostic Measure for Autism Spectrum Disorders

    Science.gov (United States)

    Luyster, Rhiannon; Gotham, Katherine; Guthrie, Whitney; Coffing, Mia; Petrak, Rachel; Pierce, Karen; Bishop, Somer; Esler, Amy; Hus, Vanessa; Oti, Rosalind; Richler, Jennifer; Risi, Susan; Lord, Catherine

    2009-01-01

    The Autism Diagnostic Observation Schedule (ADOS; Lord et al., J Autism Dev Disord, 30(3):205-223, 2000) is widely accepted as a "gold standard" diagnostic instrument, but it is of restricted utility with very young children. The purpose of the current project was to modify the ADOS for use in children under 30 months of age. A modified ADOS, the…

  15. När himlen förbinds med jorden

    DEFF Research Database (Denmark)

    Dencik, Lars

    2013-01-01

    Artikeln undersøger religionens tislstædeværelse i politiken. Det skelnes mellem religion og religiositet. Udfra det analyseres og beskrives hvordan religiøsitet fremmer våldelige konflikter og får dem at gå i hårdknude....

  16. Experiment list: SRX982082 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available elopmental stage=L3 || matching input raw data file=Input_SET4_L3_Rep1_1.fastq.gz,Input_SET4_L3_Rep1_2.fastq...0me1 SET4 L3 Rep1 ChIPSeq; Caenorhabditis elegans; ChIP-Seq source_name=whole worms || strain=MT14911 || dev

  17. The Role of SncN and Ski in Mammary Epithelial Cell Transformation

    Science.gov (United States)

    2005-07-01

    Lodish , H. F. (2001) Cytokine Growth Factor Rev. 12, 1–8. 7. Luo, K. (2004) Curr. Opin. Genet. Dev. 14, 65–70. 8. Akiyoshi, S., Inoue, H., Hanai, J...Liu, X., Ng-Eaton, E., Lodish , H. F. & Weinberg, R. A. (1999) Proc. Natl. Acad. Sci. USA 96, 12442–12447. 16. Wan, Y., Liu, X. & Kirschner, M. W

  18. Experiment list: SRX882884 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX882884 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth... TC414-013 HiSeq strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=03/20/

  19. Experiment list: SRX879756 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX879756 mm9 No description NA Liver Liver MeSH Description=The number of offspring produced at one birth... strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=female || tissue=liver || birth_date=03/25/11 || death_da

  20. Experiment list: SRX882871 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX882871 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth...ver TC414-007 HiSeq strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=02/

  1. Experiment list: SRX879758 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX879758 mm9 No description NA Liver Liver MeSH Description=The number of offspring produced at one birth...train=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=09/06/10 || death_date=0

  2. Experiment list: SRX882974 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX882974 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth...GAIIx strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=03/20/13 || death

  3. Experiment list: SRX879757 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX879757 mm9 No description NA Liver Liver MeSH Description=The number of offspring produced at one birth...rain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=09/14/10 || death_date=08

  4. Experiment list: SRX882973 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX882973 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth...C414-009 strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=02/24/13 || de

  5. Experiment list: SRX882918 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX882918 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth...C414-007 GAIIx strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=02/24/13

  6. Experiment list: SRX883013 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX883013 mm9 DNase-seq DNase-Seq Liver Liver MeSH Description=The number of offspring produced at one birth...TC414-014 strain=C57Bl/6 x Sv/129 || dev_stage=adult || sex=male || tissue=liver || birth_date=03/20/13 || d

  7. Cassandra high availability

    CERN Document Server

    Strickland, Robbie

    2014-01-01

    If you are a developer or DevOps engineer who understands the basics of Cassandra and are ready to take your knowledge to the next level, then this book is for you. An understanding of the essentials of Cassandra is needed.

  8. Assessment of the effective dose in supine, prone, and oblique positions in the maxillofacial region using a novel combined extremity and maxillofacial cone beam computed tomography scanner

    NARCIS (Netherlands)

    Koivisto, J.; Wolff, J.; Järnstedt, J.; Dastidar, P.; Kortesniemi, M.

    2014-01-01

    Objective The objectives of this study were to assess the organ and effective doses (International Commission on Radiological Protection [ICRP] 103 standard) resulting from supine, prone, and oblique phantom positions in the maxillofacial region using a novel cone beam computed tomography (CBCT) dev

  9. Does WISC-IV Underestimate the Intelligence of Autistic Children?

    Science.gov (United States)

    Nader, Anne-Marie; Courchesne, Valérie; Dawson, Michelle; Soulières, Isabelle

    2016-01-01

    Wechsler Intelligence Scale for Children (WISC) is widely used to estimate autistic intelligence (Joseph in The neuropsychology of autism. Oxford University Press, Oxford, 2011; Goldstein et al. in "Assessment of autism spectrum disorders." Guilford Press, New York, 2008; Mottron in "J Autism Dev Disord" 34(1):19-27, 2004).…

  10. The Sky is not the Limit

    DEFF Research Database (Denmark)

    Lund, Morten; Nielsen, Christian

    2012-01-01

    This paper is account of a company that is in the process of writing its first prospectus and therefore has an aim of conveying a true and fair picture of its future prospects to existing partners and potential investors. Via a longitudinal case study over a period of 2½ years, we studied the dev...

  11. Methods and tools for integrated assessment of land use policies on sustainable development in developing countries

    NARCIS (Netherlands)

    Reidsma, P.; König, H.; Feng, S.; Bezlepkina, I.; Nesheim, I.; Bonin, M.; Sghaier, M.; Purushothaman, S.; Sieber, S.; Ittersum, van M.K.; Brouwer, F.M.

    2011-01-01

    For stimulating sustainable development in developing countries, land use patterns and land use changes are considered critical, and therefore effective and efficient land use policies are needed. In this paper we present a methodological framework that has been developed in a joint European and dev

  12. Location choice of academic entrepreneurs: Evidence from the US biotechnology industry

    NARCIS (Netherlands)

    Kolympiris, C.; Kalaitzandonakes, N.; Miller, D.

    2015-01-01

    Where knowledge-based firms are located is important because entrepreneurship, firm creation and innovation are typically associated with regional economic development, wealth creation and increased employment. In this paper we examine where academic entrepreneurs locate their firms. We begin by dev

  13. GABAA Receptor-Mediated Activity in a Model of Cortical Dysplasia

    Science.gov (United States)

    2012-06-29

    Daza RA, Rubenstein JL, Stunnenberg H, Olavarria JF, Englund C (2003) Beyond laminar fate: toward a molecular classification of cortical projection...pyramidal neurons. Dev Neurosci 25:139-151.   167   Hevner RF, Daza RA, Englund C, Kohtz J, Fink A (2004) Postnatal shifts of interneuron

  14. Ultrathin Compound Semiconductor on Insulator Layers for High-Performance Nanoscale Transistors

    Science.gov (United States)

    2010-11-11

    substrate for low power logic applications. IEEE IEDM Tech. Digest 2009, 319–322 (2009). 11. Javorka, P. et al. AlGaN/ GaN HEMTs on (111) silicon...of sub-100 nm InAs HEMTs on InP substrate for future logic applications. IEEE Trans. Electron. Dev. 57, 1504–1511 (2010). 24. Lundstrom, M

  15. Evaluation of 1066 ToxCast Chemicals in a human stem cell assay for developmental toxicity (SOT)

    Science.gov (United States)

    To increase the diversity of assays used to assess potential developmental toxicity, the ToxCast chemical library was screened in the Stemina devTOX quickPREDICT assay using human embryonic stem (hES) cells. A model for predicting teratogenicity was based on a training set of 23 ...

  16. Analysis of the Decision and Verification Stockmarket Tasks Using Additive Stage Process Methods.

    Science.gov (United States)

    1981-06-01

    58224 2 3700 TCHTWiTTGH Stop 32 Sheppard AFB, TX 76311 Marines Other DoD H. William Greenup 12 Defense Technical Information Center Education Advisor...Psychology Campus Box 346 Dr. Erik McWilliams University of Colorado Science Education Dev. and Research Boulder, CO 80309 National Science Foundation

  17. Individual Differences in Dual Task Performance.

    Science.gov (United States)

    1981-06-10

    Marty Rockway Technical Director AFHRL(OT) Williams AFB. AZ 58224 3700 TCHTW/TTGH Stop 32 Sheppard AFB, TX 76311 b mw-- w 9age 5 CoastGuard Other DoD...Washington, DC 20350 Dr. David Kieras Department of Psychology 1 Dr. Erik McWilliams University of Arizona Science Education Dev. and Research Tuscon

  18. Final Report for Contract N00014-78-C-0022 for the Period 1 October 1977-30 September 1980.

    Science.gov (United States)

    1981-01-26

    AZ 58224 Alexandria, VA 22333 2 3700 TCHTW/TTGH Stop 32 Sheppard AFB, TX 76311 1 Jack A. Thorp, Maj., USAF Life Sciences Directorate AFOSR Bolling...OF COLORADO 1 Dr. Erik McWilliams BOULDER, CO 80309 Science Education Dev. and Research National Science Foundation 1 Dr. Steven E. Poltrock

  19. Instrumentation and Software for the Collection Analysis, and Interpretation of Eye Movement Data During Reading.

    Science.gov (United States)

    1981-06-01

    70J stop n National Science Foundation Sheppard AIF, 1 76311 Washington. DC 20550 1 or. Joseph Psotka National Institute of Education 1200 19th St...Ion Govt Non oovt Dr. Erik McWilliams Dr. Fred Reif Science Education Dev. and Research SESAME National Science Foundation c/o physics Deparment

  20. Spatial Selectivity in Visual Search.

    Science.gov (United States)

    1980-10-01

    Technical Director AFHRL(OT) Williams AFB, AZ 58224 2 3700 TCHTW/TTGH Stop 32 Sheppard AFB, TX 76311 1 Jack A. Thorp, Maj., USAF Life Sciences...Boulder, CO 80302 Dr. Erik McWilliams Science Education Dev. and Research 1 DR. PETER POLSON National Science Foundation DEPT. OF PSYCHOLOGY

  1. The Future of Testing: A Research Agenda for Cognitive Psychology and Psychometrics.

    Science.gov (United States)

    1981-02-01

    EISENHOWER AVENUE Williams AFB, AZ 58224 ALEXANDRIA, VA 22333 2 3700 TCHTW/TTGH Stop 32 1 Dr. Michael Kaplan Sheppard AFB, TX 76311 U.S. ARMY RESEARCH...OF COLORADO BOULDER, CO 80309 Dr. Erik McWilliams Science Education Dev. and Research 1 Dr. Steven E. Poltrock National Science Foundation Department

  2. Strategies for Abstracting Main Ideas from Simple Technical Prose.

    Science.gov (United States)

    1981-11-11

    Corps Patters AFOSR Code lOOM Bolling AFB, DC 20112 Office of Naval Reseprch 800 K. Quincy St. 2 3700 TCHT/TTGH Stop 32 Arlington, VA 22217 Sheppard AFB...PETER POLSON Dr. Erik McWilliams DEPT. OF PSYCHOLOGY Science Education Dev. and Research UNIVERSITY OF COLORADO National Science Foundation BOULDER, CO

  3. Studies in Plan Construction. II. Novice Design Behavior.

    Science.gov (United States)

    1980-12-01

    Marty Rockway Technical Director AFHRL(OT) Williams AFB, AZ 58224 2 3700 TCHTW/TTGH Stop 32 Sheppard AFB, TX 76311 1 Jack A. Thorp, Maj., USAF Life...University of Oregon 1 Dr. Erik McWilliams Eugene, OR 97403 Science Education Dev. and Research National Science Foundation Dr. Walter Kintsch

  4. Analysis of irradiation processes for laser-induced periodic surface structures

    NARCIS (Netherlands)

    Eichstädt, J.; Huis in 't Veld, A.J.

    2013-01-01

    The influence of errors on the irradiation process for laser-induced periodic surface structures (LIPSS) was studied theoretically with energy density simulations. Therefore an irradiation model has been extended by a selection of technical variations. The influence of errors has been found in a dev

  5. Appi - tarbijast võlgnik kolis välismaale! : kommentaar Riigikohtu lahenditele asjades 3-2-1-114-12 ja 3-2-1-123-12 / Karin Sein

    Index Scriptorium Estoniae

    Sein, Karin, 1974-

    2013-01-01

    Riigikohtu lahendist 3-2-1-114-12, milles vaieldi füüsilisest isikust võlgniku pankroti väljakuulutamise kohtualluvuse üle. Lahendist 3-2-1-123-12, milles vaieldi, kas ja millistel tingimustel on Eesti kohus pädev läbi vaatama hagi Eestist lahkunud tarbijast krediidisaaja vastu

  6. Recent advances in silage microbiology

    Science.gov (United States)

    Recent advances in our understanding of silage microbiology are reviewed. The ability to extract microbial DNA from silages, amplify portions of DNA, and use the amplified regions to identify strains of microorganisms is at the core of the changes occurring recently in silage microbiology. These dev...

  7. Piraatlus Guinea lahes ja Nigeerias / Eero Tepp

    Index Scriptorium Estoniae

    Tepp, Eero

    2013-01-01

    Guinea lahes lokkava piraatluse põhjused ja tegurid, mis seda soodustavad: seaduselüngad, looduslikud tingimused, ebapädev korrakaitse, poliitiline olustik, kultuuriline vastuvõetavus, majanduslik tasuvus. Sõjalised ja mittesõjalised meetmetest, mida rakendatakse piraatlusevastases võitluses

  8. Disease: H00632 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 51C:307-17 (2009) PMID:9735377 (description) Casey B Two rights make a wrong: human left-right malformations...etics of human left-right axis malformations. Semin Cell Dev Biol 9:89-99 (1998) PMID:11471159 (description)

  9. Model of the human controller of a dynamic system

    NARCIS (Netherlands)

    Wewerinke, P.H.

    1986-01-01

    In de last two decades considerable research effort has been devoted to the study of human involvement in dynamic systems. Especially human control behavior has been investigated, but in the restricted sense of continuous regulating against random disturbances, so as to minimize the system state dev

  10. Conventional Anchor Test Results at San Diego and Indian Island

    Science.gov (United States)

    1980-07-01

    lines passed through open chocks welded at opposite ends of the barge. A crane barge was used to install and recover all test anchors at each site...DEPT OF FISH & GAME Long Beach CA (Marine Tech Info Ctr) CALIF. DEPT OF NAVIGATION & OCEAN DEV. Sacramento, CA (G. Armstrong) CALIF. MARITIME ACADEMY

  11. Comparing Identity Management Frameworks in a Business Context

    NARCIS (Netherlands)

    Hoepman, H.J.; Joosten, H.J.M.; Siljee, J.

    2009-01-01

    Several frameworks for identity management exist, each of them with its own distinguishing features. These frameworks are complex however, and their features not easily understood. This makes it hard for businesses to understand the intricacies, and difficult to select and deploy one. This paper dev

  12. In Situ/on-Site Biodegradation of Refined Oils and Fuels (A Technology Review). Volume 1.

    Science.gov (United States)

    1992-06-01

    decreasing counts with depth, ranging from zero to 100. 3.1.1.5 Counts in Contaminated Soil Microbial numbers and activity are initially depressed by even...1982. The groundwater aquifer microbiota : Biomass, community structure and nutritional status. Dev. Ind. Microbiol. 24:201-211. Wickerham, L.J. 1951

  13. The European arrest warrant and domestic legal orders : tensions between mutual recognition and fundamental rights: the Italian Case

    NARCIS (Netherlands)

    Marin, Luisa

    2008-01-01

    This article presents and discusses some recent decisions on the European Arrest Warrant by the Italian higher courts, the Constitutional Court and the Court of Cassation. Though not as challenging to the EAW as the ‘first round’ of European judgments of 2005, they bring however some interesting dev

  14. The Autism-Spectrum Quotient and Visual Search: Shallow and Deep Autistic Endophenotypes

    Science.gov (United States)

    Gregory, B. L.; Plaisted-Grant, K. C.

    2016-01-01

    A high Autism-Spectrum Quotient (AQ) score (Baron-Cohen et al. in "J Autism Dev Disord" 31(1):5-17, 2001) is increasingly used as a proxy in empirical studies of perceptual mechanisms in autism. Several investigations have assessed perception in non-autistic people measured for AQ, claiming the same relationship exists between…

  15. Survey of ICT and Education in Africa : Cape Verde Country Report

    OpenAIRE

    Tutu, Osei Agyeman

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev)-supported survey of Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Cape Verde has made significant strides in the implementation of ICTs in education. The drawback o...

  16. Cooperation between information system development and operations: a literature review

    NARCIS (Netherlands)

    Erich, Floris; Amrit, Chintan; Daneva, Maya

    2014-01-01

    Software development can profit from improvements in the deployment and maintenance phases. DevOps improves these phases through a collection of principles and practices, centered around close collaboration between Development and Operations personnel. Both sides have paid little attention to issues

  17. On the Integration of Automatic Deployment into the ABS Modeling Language

    NARCIS (Netherlands)

    Gouw, C.P.T. de; Lienhardt, M.; Mauro, J.; Nobakht, B.; Zavattaro, G.; Dustdar, S.; Leymann, F.; Villari, M.

    2015-01-01

    In modern software systems, deployment is an integral and critical part of application development (see, e.g., the DevOps approach to software development). Nevertheless, deployment is usually overlooked at the modeling level, thus losing the possibility to perform deployment conscious decisions dur

  18. Multilayer Aluminum Oxynitride Capacitors for Higher Energy Density, Wide Temperature Applications (Preprint)

    Science.gov (United States)

    2007-02-01

    IEEE Trans. Electr. Dev., 50, 1214-1219 (2003). 17 W.S. Lau, M.T.C. Perera, P. Babu, A.K. Ow, T. Han, N.P. Sandler, C.H. Tung, T.T. Sheng, P.K. Chu, Japanese Journal of Applied Physics , Part 2, 37, L435 (1998).

  19. Insight into Skin Tumorigenesis Highlighting the Function of Epigenetic Regulators in SCC Formation

    Science.gov (United States)

    2013-10-01

    Epigenetic regulation of cellular memory by the polycomb and trithorax group proteins . Annu Rev Genet 2004;38:413-443...lys 27. Genes Dev 2003;17:1823-1828. 9 Francis NJ, Kingston RE, Woodcock CL: Chromatin compaction by a polycomb group protein complex. Science...Highlighting the Function of Epigenetic Regulators in SCC Formation PRINCIPAL INVESTIGATOR: Jisheng Zhang CONTRACTING

  20. Proceedings of the 2011 AFMS Medical Research Symposium. Volume 4. Healthcare Informatics Track

    Science.gov (United States)

    2011-08-02

    Application query yields the following•: o p (mean SBP ofall ADAF) = 115.0 o .’f (mean SBP of 1000 PH personnel) = 115.5 o s (stan dard dev iation of...o IOT &E fai lure rate (50%) suggest deficiencies in DT&E processes o Suitability failures are increasing Recommendations o Integrate RAM in

  1. Beyond Technology Readiness Levels for Software: U.S. Army Workshop Report

    Science.gov (United States)

    2010-12-01

    for software that may be ready to achieve the Dev R-044 | 21 s main is rt early, ost ept of ges for stem is can be ping is f the life...Assurance IDE Integrated Development Environment IOC Initial Operational Capability IOT &E Initial Operational Test and Evaluation CMU/SEI-2010-TR-044

  2. Command and Control Rapid Prototyping Continuum (C2RPC): The Framework for Achieving a New C2 Strategy

    Science.gov (United States)

    2011-06-01

    Program of Record TRL 8-9 MTC2 DT/OT Process C2 Release Distribution POR ‘Pull’ • S&T’s job is complete at the tech dev stage • Implementation of...PILLARS 14 IT Acquisition Life Cycle Alignment Nat’l Defense Authorization Act 2010 IOT &E RITE Life Cycle (System Support Activity) Design & Procure

  3. Assessing Weapon System Acquisition Cycle Times: Setting Program Schedules

    Science.gov (United States)

    2015-06-01

    capability gaps (and when projected?) Materiel Sol. needed Materiel Dev . Decision Analysis of Alternatives (AoA) • Trade offs • Capability vs. cost...Force Protection Capability IDA Institute for Defense Analyses IOC Initial Operational Capability IOT &E Initial Operational Testing and Evaluation

  4. USMC Initiatives in Energy and Power

    Science.gov (United States)

    2010-05-01

    PG-11 MAGTF C2, Weapons and Sensors Dev & Int PG-12 Communications, Intel, And Networking PG-13 Infantry Weapons Systems PG-14 Armor and Fire...Production IOT &E - Initial Operation Test & Evaluation LD - Logistics Demonstration LRIP - Low Rate Initial Product PAC - Post Award Conference PDR...and Manufacturing Demonstration LRIP/ IOT &E System Integration System Demonstration Production & Deployment Operations & Support FRP

  5. Defense Acquisition Research Journal. Volume 21, Number 2, Issue 69

    Science.gov (United States)

    2014-04-01

    Dev . . . . . . . . . . . . . . . . . . . . . Development DoD . . . . . . . . . . Department of Defense DT/OT . . . . . . . .Developmental Testing...Integrated Fire Control Network IMU . . . . . . . . . . Inertial Measurment Unit IOC . . . . . . .Initial Operational Capability IOT ...Design Review; FOC = Full Operating Capability; FRP = Full- Rate Production; IOC = Initial Operating Capability; IOT &E = Initial Operational Test

  6. Excalibur Precision 155mm Projectiles (Excalibur)

    Science.gov (United States)

    2013-12-01

    Year DAMIR - Defense Acquisition Management Information Retrieval Dev Est - Development Estimate DoD - Department of Defense DSN - Defense Switched...the Increment Ib First Article Test (FAT) and Initial Operational Test and Evaluation ( IOT &E). Throughout FY 2013, Increment Ib successfully...Pre- IOT &E Live Fire, Sequential Environmental Testing for Safety, Sequential Environmental Testing for Performance, and FAT. These tests have

  7. Antecedents to Organizational Performance: Theoretical and Practical Implications for Aircraft Maintenance Officer Force Development

    Science.gov (United States)

    2015-03-26

    process and going to be going into IOT &E. Learning in depth about the acquisitions process, how we fit in, and how we can make the system work...Building a learning organization. Org Dev & Trng, 6E (Iae) , 274. 26. Gefen, D., & Straub, D. (2005). A Practical Guide to Factorial Validity Using PLS

  8. P-8A Poseidon Multi-Mission Maritime Aircraft (P-8A)

    Science.gov (United States)

    2013-12-01

    Information Retrieval Dev Est - Development Estimate DoD - Department of Defense DSN - Defense Switched Network Econ - Economic Eng - Engineering Est...most significant remaining System Development & Demonstration milestones, including completion of Initial Operational Test and Evaluation ( IOT &E...and Evaluation completed in February 2013. IOT &E completed in March 2013. The IOT &E report released by Commander, Operational Test Force in July

  9. Mitte päris 1989, aga ka mitte lootusetu / Matti Maasikas

    Index Scriptorium Estoniae

    Maasikas, Matti

    2011-01-01

    Teatavast sarnasusest hoolimata pole praegusel araabia revolutsioonil 20 aasta taguse Ida-Euroopa vabadusliikumisega palju ühist, pädev pole seda võrrelda 1979. a. Iraani islamirevolutsiooniga. Araabia ühiskonnas on võimalik demokraatia ning EL ja USA saavad demokraatia jaoks vajalike institutsioonide, õigusriigi, hea valitsemistava juurutamisel appi tulla

  10. Long-term salinity development in a lysimeter experiment.

    NARCIS (Netherlands)

    Hoorn, van J.W.; Katerji, N.; Hamdy, A.

    1997-01-01

    Over a period of 6 years, various crops were grown in tanks, filled with loam and clay, and were irrigated with water of three different levels of salinity. A combination of soil water sampling, salt balance and salt model was used to study the change in the composition of the soil water and the dev

  11. Instant standard concept for data standards development

    NARCIS (Netherlands)

    Folmer, E.; Kulcsar, I.Z.; Roes, J.

    2013-01-01

    This paper presents the current results of an ongoing research about a new data standards development concept. The concept is called Instant Standard referring to the pressure that is generated by shrinking the length of the standardization process. Based on this concept it is estimated that the dev

  12. The many faces of airway inflammation - Asthma and chronic obstructive pulmonary disease

    NARCIS (Netherlands)

    O'Byrne, PM; Postma, DS

    1999-01-01

    Airway diseases, predominantly asthma and chronic obstructive pulmonary disease (COPD), are among the world's most prevalent diseases. The prevalence of asthma has been incasing over the past 20 yr in most countries where this has been studied, and it affects up to 10% of the populations of most dev

  13. Stochastic Parameterization: Towards a new view of Weather and Climate Models

    NARCIS (Netherlands)

    Crommelin, D.T.; et al, not CWI

    2015-01-01

    The last decade has seen the success of stochastic parameterizations in short-term, medium-range and seasonal ensembles: operational weather centers now routinely use stochastic parameterization schemes to better represent model inadequacy and improve the quantification of forecast uncertainty. Dev

  14. Scaling up tests on virulence of the cassava green mite fungal pathogen Neozygites tanajoae (Entomophthorales: Neozygitaceae) under controlled conditions: first observations at the population level

    NARCIS (Netherlands)

    Hountondji, F.C.C.; Hanna, R.; Cherry, A.J.; Sabelis, M.W.; Agboton, B.; Korie, S.

    2007-01-01

    Virulence of entomopathogens is often measured at the individual level using a single host individual or a group of host individuals. To what extent these virulence assessments reflect the impact of an entomopathogen on their host in the field remains largely untested, however. A methodology was dev

  15. The European Romani Women's Movement: The struggle for human rights

    OpenAIRE

    Rita Izsák

    2009-01-01

    Rita Izsák discusses the International Romani Women's Network (IRWN), the first registered international umbrella organization representing Romani women of all European Romani groups. She examines how IRWN is promoting women's rights, and the connection between mainstream feminist movements and the Romani movement. Development (2009) 52, 200–207. doi:10.1057/dev.2009.9

  16. Implementing an Evidence Based Preceptorship Program in a Military Center

    Science.gov (United States)

    2014-11-05

    Basil Blackwell; 1986. • Elmers CR. The role of preceptor and nurse leader in developing intensive care unit competency. Crit Care Nurs Q. Jan-Mar...method to enhance clinical teaching. J Nurs Staff Dev. Jan-Feb 2007;23(1):1-9; quiz 10-11. • Moore M. Developing the preceptorship evaluation survey

  17. Software product lines : Organizational alternatives

    NARCIS (Netherlands)

    Bosch, J

    2001-01-01

    Software product lines enjoy increasingly wide adoption in the software industry. Most authors focus on the technical and process aspects and assume an organizational model consisting of a domain engineering unit and several application engineering units. In our cooperation with several software dev

  18. Disease: H00019 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D010190 PMID:12459728 (gene, tumor type) Bardeesy N, DePinho RA. Pancreatic cancer biology and genetics. Nat...tanger BZ, Bardeesy N, Depinho RA. Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev 20:12

  19. Development of novel repellents using structure-activity modeling of compounds in the USDA archival database

    Science.gov (United States)

    The United States Department of Agriculture (USDA) has developed repellents and insecticides for the U.S. military since 1942. Repellency and toxicity data for over 30,000 compounds are contained within the USDA archive. Repellency data from subsets of similarly structured compounds were used to dev...

  20. Survey of ICT and Education in Africa : Libya Country Report

    OpenAIRE

    Hamdy, Amr

    2007-01-01

    This short country report, a result of larger Information for Development Program (infoDev) - supported survey of the Information and Communication Technologies (ICT) in education in Africa, provides a general overview of current activities and issues related to ICT use in education in the country. Libya boasts the highest literacy rate in the Arab world, and the United Nations (UN's) Huma...

  1. Financial Services and Emerging Markets

    NARCIS (Netherlands)

    B. Karreman (Bas)

    2011-01-01

    textabstractThis study addresses the organization and strategy of firms in emerging markets with an explicit application to financial services. Given the relevance of a well-functioning financial system for economic growth, understanding the organization and strategy of firms contributing to the dev

  2. Housing policy socialization and de-commodification in South Korea

    NARCIS (Netherlands)

    R. Ronald; H. Lee

    2012-01-01

    South Korea has undergone significant housing system transformations in recent decades involving radical expansions in state housing provision. Growth in social forms of public housing ostensibly contradicts the neoliberal trend toward the privatization of social housing sectors elsewhere in the dev

  3. Resonance and Transcendence of a Bodily Presence

    DEFF Research Database (Denmark)

    Petersen, Rikke Munck; Farsø, Mads

    2016-01-01

    This article elucidates how film may offer itself as ‘resonance tool’ for both representation and conception of space that can strengthen an alternative, phenomenological and haptic position of transcendence in architecture, a position from which landscapes and cities are thought, planned and dev...

  4. Automatic discrimination between laughter and speech

    NARCIS (Netherlands)

    Truong, K.; Leeuwen, D. van

    2007-01-01

    Emotions can be recognized by audible paralinguistic cues in speech. By detecting these paralinguistic cues that can consist of laughter, a trembling voice, coughs, changes in the intonation contour etc., information about the speaker’s state and emotion can be revealed. This paper describes the dev

  5. Fluorescence-Based Reporter for Gauging Cyclic Di-GMP Levels in Pseudomonas aeruginosa

    DEFF Research Database (Denmark)

    Rybtke, Morten T.; Borlee, Bradley R.; Murakami, Keiji

    2012-01-01

    The increased tolerance toward the host immune system and antibiotics displayed by biofilm-forming Pseudomonas aeruginosa and other bacteria in chronic infections such as cystic fibrosis bronchopneumonia is of major concern. Targeting of biofilm formation is believed to be a key aspect in the dev...

  6. CERN Computing Colloquia Spring Series: IT Security - A High-Performance Pattern Matching Engine for Intrusion Detection

    CERN Document Server

    CERN. Geneva

    2006-01-01

    The flexible and modular design of the engine allows a broad spectrum of applications, ranging from high-end enterprise level network devices that need to match hundreds of thousands of patterns at speeds of tens of gigabits per second, to low-end dev...

  7. Using complex plant pedigrees to map valuable genes

    NARCIS (Netherlands)

    Jannink, Jean-Luc; Bink, Marco C.A.M.; Jansen, Ritsert C.

    2001-01-01

    Statistical methods pioneered by human and animal geneticists use marker and pedigree information to detect quantitative trait loci within complex pedigrees. These methods, adapted to plants, promise to expand the range of data useful for identifying the genetic factors influencing plant growth, dev

  8. Coordination and Cooperation Problems in Network Good Production

    NARCIS (Netherlands)

    A. Knigge (Antonie); V.W. Buskens (Vincent)

    2010-01-01

    textabstractIf actors want to reach a particular goal, they are often better off forming collaborative relations and investing together rather than investing separately. We study the coordination and cooperation problems that might hinder successful collaboration in a dynamic network setting. We dev

  9. Getting started with tmux

    CERN Document Server

    Quinn, Victor

    2014-01-01

    The book is intended for software developers, DevOps engineers, and other professionals who make heavy use of the terminal in their daily workflow. Some familiarity with the terminal is useful but no prior experience with tmux or other terminal multiplexers (such as GNU Screen) is required.

  10. A Pull-in Based Test Mechanism for Device Diagnostic and Process Characterization

    NARCIS (Netherlands)

    Rocha, L.A.; Mol, L.; Cretu, E.; Wolffenbuttel, R.F.; Machado da Silva, J.

    2008-01-01

    A test technique for capacitive MEMS accelerometers and electrostatic microactuators, based on the measurement of pull-in voltages and resonance frequency, is described. Using this combination of measurements, one can estimate process-induced variations in the device layout dimensions as well as dev

  11. Cardiac responses of vagus nerve stimulation: Intraoperative bradycardia and subsequent chronic stimulation

    NARCIS (Netherlands)

    Ardesch, J.J.; Buschman, H.P.J.; Burgh, van der P.H.; Wagener-Schimmel, L.J.; Aa, van der H.E.; Hageman, G.

    2007-01-01

    OBJECTIVES: Few adverse events on heart rate have been reported with vagus nerve stimulation (VNS) for refractory epilepsy. We describe three cases with intraoperative bradycardia during device testing. PATIENTS AND METHODS: At our hospital 111 patients have received a VNS system. Intraoperative dev

  12. Assessing Recollection and Familiarity in Low Functioning Autism

    Science.gov (United States)

    Ni Chuileann, Susan; Quigley, Jean

    2013-01-01

    Methods to assess recollection and familiarity separately in autism spectrum disorder were recently developed and piloted (Bigham et al. in J Autism Dev Disord 40:878-889, 2010). The preliminary data obtained via these methods showed that whereas recollection was mildly impaired in high functioning autism, familiarity was spared. The current study…

  13. INTERIM REPORT, DEVELOP A SAMPLING STRATEGY: PREPARE TO IMPLEMENT A COHORT STUDY OF CHILDREN'S ENVIRONMENTAL HEALTH

    Science.gov (United States)

    OverviewThe goal of the National Children's Study (NCS) is to collect information on environmental andsocial factors in the lives of children, starting before birth and continuing until age 21, to informresearchers about their effects on the health and dev...

  14. Evaluation of the ADOS Revised Algorithm: The Applicability in 558 Dutch Children and Adolescents

    Science.gov (United States)

    de Bildt, Annelies; Sytema, Sjoerd; van Lang, Natasja D. J.; Minderaa, Ruud B.; van Engeland, Herman; de Jonge, Maretha V.

    2009-01-01

    The revised ADOS algorithms, proposed by Gotham et al. (J Autism Dev Disord 37:613-627, 2007), were investigated in an independent sample of 558 Dutch children (modules 1, 2 and 3). The revised algorithms lead to better balanced sensitivity and specificity for modules 2 and 3, without losing efficiency of the classification. Including the…

  15. Küünlavalgus soojendab hinge / Kadri Tramm

    Index Scriptorium Estoniae

    Tramm, Kadri

    2014-01-01

    Erivärvilised ja -kujulised küünlad annavad hubast valgust ja on ka pilkupüüdev sisekujunduselement. Nõu annavad Kaubamaja Kodumaailma teenindusjuht Aires Rühka ja Scheteligi hulgimüügi esindaja Janika Paat

  16. The Broad Autism Phenotype Questionnaire: Mothers versus Fathers of Children with an Autism Spectrum Disorder

    Science.gov (United States)

    Seidman, Ifat; Yirmiya, Nurit; Milshtein, Shahaf; Ebstein, Richard P.; Levi, Shlomit

    2012-01-01

    Parents of individuals with autism were examined using the Broad Autism Phenotype Questionnaire (BAPQ; Hurley et al. in "J Autism Dev Disord" 37:1679-1690, 2007) assessing BAP-related personality and language characteristics. The BAPQ was administered to parents as a self-report and as an informant (spouse)-based measure. Results indicated the…

  17. Bicycle Rider Control: Observations, Modeling & Experiments

    NARCIS (Netherlands)

    Kooijman, J.D.G.

    2012-01-01

    Bicycle designers traditionally develop bicycles based on experience and trial and error. Adopting modern engineering tools to model bicycle and rider dynamics and control is another method for developing bicycles. This method has the potential to evaluate the complete design space, and thereby dev

  18. Membrane contactor applications

    NARCIS (Netherlands)

    Klaassen, R.; Feron, P.H.M.; Jansen, A.

    2008-01-01

    In a membrane contactor the membrane separation is completely integrated with an extraction or absorption operation in order to exploit the benefits of both technologies fully. Membrane contactor applications that have been developed can be found in both water and gas treatment. Several recently dev

  19. The Shock and Vibration Digest, Volume 18, Number 3

    Science.gov (United States)

    1986-03-01

    Space Trusses - . J.A. Teixeira de Freitas, J.P.B. Moitinho de ,-. Almeida, F.B.E. Virtuoso .-. . Universidade Tecnica de Lisboa, Lisbon, Portugal 86...34 Manual on, Aernelasticity," Part U, Aero- dynamic Aspects, Advisory Unfortunately, such information is Group Aeronaut. Res. Dev. often unreliable

  20. Public Participation and the Private Sector: The Role of Multilateral Development Banks in the Evolution of International Legal Standards

    NARCIS (Netherlands)

    D.D. Bradlow (Daniel D.); M.S. Chapman (Megan)

    2011-01-01

    markdownabstract__Abstract__ This paper systematically describes the public participation standards currently applied by multilateral development banks (MDBs) to the private sector and seeks to identify emerging trends and areas for further development or improvement. It begins by outlining the dev

  1. Cultural tailoring for the promotion of Hepatitis B screening in Turkish Dutch: A protocol for a randomized controlled trial

    NARCIS (Netherlands)

    O. de Zwart (Onno); J.P. Mackenbach (Johan); J.H. Richardus (Jan Hendrik); Y.J.J. van der Veen (Ytje)

    2010-01-01

    textabstractBackground. Chronic hepatitis B virus infection (HBV) is an important health problem in the Turkish community in the Netherlands, and promotion of screening for HBV in this risk group is necessary. An individually tailored intervention and a culturally tailored intervention have been dev

  2. Total uncertainty of low velocity thermal anemometers for measurement of indoor air movements

    DEFF Research Database (Denmark)

    Jørgensen, F.; Popiolek, Z.; Melikov, Arsen Krikor

    2004-01-01

    For a specific thermal anemometer with omnidirectional velocity sensor the expanded total uncertainty in measured mean velocity Û(Vmean) and the expanded total uncertainty in measured turbulence intensity Û(Tu) due to different error sources are estimated. The values are based on a previously dev...

  3. Information systems for mental health in six low and middle income countries : Cross country situation analysis

    NARCIS (Netherlands)

    Upadhaya, Nawaraj; Jordans, Mark J D; Abdulmalik, Jibril; Ahuja, Shalini; Alem, Atalay; Hanlon, Charlotte; Kigozi, Fred; Kizza, Dorothy; Lund, Crick; Semrau, Maya; Shidhaye, Rahul; Thornicroft, Graham; Komproe, Ivan H.; Gureje, Oye

    2016-01-01

    Background: Research on information systems for mental health in low and middle income countries (LMICs) is scarce. As a result, there is a lack of reliable information on mental health service needs, treatment coverage and the quality of services provided. Methods: With the aim of informing the dev

  4. Farmer’s views and values to focus on cattle conservation policies: the case of eight European countries

    NARCIS (Netherlands)

    Gandini, G.; Martin-Collado, D.; Colinet, F.; Duclos, D.; Hiemstra, S.J.; Soini, K.; Diaz, C.

    2012-01-01

    Our aim was to identify elements useful in designing policies and programmes for conservation of farm animal genetic resources, taking as case study a group of European local cattle breeds. We first investigated the implications of differences among countries in the policies and programmes to be dev

  5. Performance of controlled atmosphere/heating block systems for assessing insect thermotolerance

    Science.gov (United States)

    Heated controlled atmosphere (CA) treatments have potential as alternatives to chemical fumigation for disinfesting postharvest stored products. To determine accurately the minimal thermal requirements to kill target insects over a wide range of temperatures and CA conditions, it is desirable to dev...

  6. Developing Linux kernel space device driver

    Institute of Scientific and Technical Information of China (English)

    Zheng Wei; Wang Qinruo; Wu Naiyou

    2003-01-01

    This thesis introduces how to develop kernel level device drivers on Linux platform in detail. On the basis of comparing proc file system with dev file system, we choose PCI devices and USB devices as instances to introduce the method of writing device drivers for character devices by using these two file systems.

  7. Experiment list: SRX1029569 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available junal epithelial cells || strain=Gata4FlapvCre+, C57BL/6 || developmental stage=Adult || protocol used=ChIP protocol was used accordi...ng to Verzi et al. (Dev Cell. 2010 Nov 16;19(5):713-26.) http://dbarchive.bioscienc

  8. Phenotype-gene: 345 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available an named peduncle during process named trichome morphogenesis for AT2G30432 Wang Shucai et al. 2007 Nov. Dev...an named peduncle during process named trichome morphogenesis http://metadb.riken.jp/db/SciNetS_ria224i/cria224u1ria224u774i AT2G30432

  9. Mechanisms of Alcohol Induced Effects on Cellular Cholesterol Dynamics

    Science.gov (United States)

    2004-09-01

    6344-6352 60. Schroeder, F., Gallegos , A. M., Atshaves, B. P., Storey, S. M., McIntosh, A. L., 57. Singh, 1. N., Sorrentino, G., Sitar, D. S., and...Azorin, I., Bendala, E., Sancho-Tello, M., Duran, J. M., Tomas , M., Gomez-Lechon, M. J., and Renau-Piqueras, J. (2000) Int. J. Dev. Biol. 44, 209-221. 29

  10. The large radius human centrifuge 'A human hypergravity habitat, H

    NARCIS (Netherlands)

    Loon, J.J.W.A. van; Wuyts, F.; Bäcker, N.; Berte, J.; Bok, K.; Bos, J.; Groen, E.; Boyle, R.; Bravenoer, N.; Eekhoff, M.; Chouker, A.; Clement, G.; Cras, P.; Denise, P.; Felsenberg, D.; Fong, K.; Fuller, C.; Heer, M.; Hinghofer-Szalkay, H.; Iwase, S.; Karemaker, J.M.; Linnarsson, D.; Lüthen, C.; Mulder, E.; Narici, M.; Norsk, P.; Paloski, W.; Rutten, M.; Saggini, R.; Stephan, A.; Ullrich, O.; Vautmans, L.; Young, L.

    2009-01-01

    Over the last decades a significant body of knowledge has been gained on the adaptation of the human body going into near weightlessness conditions as well as for the re-adaptation to 1xg Earth conditions after an orbital space flight. Ground-based paradigms for microgravity simulation have been dev

  11. Reassessing the validity of research assessments. A social experiment

    NARCIS (Netherlands)

    P.H.J. Achterberg (Peter)

    2010-01-01

    textabstractThe literature concerned with bibliometry and scientometry has been concerned with the question of how the actual output and impact of scholars can be ascertained. Whereas a situation in which scholars were mainly judged of subjective criteria was deemed undesirable, scientometry has dev

  12. Epidemiological analysis of data for scrapie in Great Britain

    NARCIS (Netherlands)

    Hagenaars, T.H.J.; Donnelly, C.; Ferguson, N.M.

    2006-01-01

    In recent years, the control or eradication of scrapie and any other transmissible spongiform encephalopathies (TSEs) possibly circulating in the sheep population has become a priority in Britain and elsewhere in Europe. A better understanding of the epidemiology of scrapie would greatly aid the dev

  13. Smad Acetylation: A New Level of Regulation in TGF-Beta Signaling

    Science.gov (United States)

    2007-07-01

    1998) Genes Dev. 12, 2114–2119 29. Nishihara, A., Hanai, J. I., Okamoto,N., Yanagisawa, J., Kato, S.,Miyazono, K., and Kawabata , M. (1998) Genes Cells...M. B., Frederick, J. P., andWang, X. F. (1998)Mol. Biol. Cell 9, 3309–3319 32. Nishihara, A., Hanai, J., Imamura, T., Miyazono, K., and Kawabata , M

  14. Data of evolutionary structure change: 1ACPA-2DEVC [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ACPA-2DEVC 1ACP 2DEV A C STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDT...HHH EEE EEEEEEE EEEEEEEEEE -------- 0 1ACP... A 1ACPA EEAEK-----IT...> ARG CA 219 LYS CA 147 THR CA 173 1ACP... A 1ACPA ELVMALEEEFDT

  15. Data of evolutionary structure change: 1ACPA-2DEVB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ACPA-2DEVB 1ACP 2DEV A B STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDT...H EEE EEEEEEE EEEEEEEEEE ------- 0 1ACP... A 1ACPA KITTV-----QAAID...> ILE CA 301 1ACP A 1ACP...ine>THR CA 171 1ACP

  16. The Learning Effects of a Multidisciplinary Professional Development Programme

    NARCIS (Netherlands)

    Visser, Talitha C.; Coenders, Fer G.M.; Pieters, Jules M.; Terlouw, Cees

    2013-01-01

    Professional development becomes relevant and effective when teachers are actively involved, collaborate, and when it is linked to teachers’ daily school practice (Hunzicker in Prof Dev Educ 37:177–179, 2011). Preparation of teachers for a curriculum implementation such as the new subject Nature, Li

  17. Physiologically based kinetic models for the alkenylbenzene elemicin in rat and human and possible implications for risk assessment.

    NARCIS (Netherlands)

    Berg, van den S.J.; Punt, A.; Soffers, A.E.M.F.; Vervoort, J.J.M.; Ngeleja, S.; Spenkelink, B.; Rietjens, I.M.C.M.

    2012-01-01

    The present study describes physiologically based kinetic (PBK) models for the alkenylbenzene elemicin (3,4,5-trimethoxyallylbenzene) in rat and human, based on the PBK models previously developed for the structurally related alkenylbenzenes estragole, methyleugenol, and safrole. Using the newly dev

  18. hEcd, A Novel Regulator of Mammary Epithelial Cell Survival

    Science.gov (United States)

    2009-09-01

    the promoter and promotion of acetylation of transcription factors and the histone proteins ( Imhof et al., 1997; Blobel, 2000; Goodman and Smolik, 2000...transformation, and development. Genes Dev. 14, 1553–1577. Imhof , A., Yang, X.J., Ogryzko, V.V., Nakatani, Y., Wolffe, A.P., and Ge, H. (1997

  19. A different development model in China’s western and eastern provinces?

    NARCIS (Netherlands)

    M.P. van Dijk (Meine Pieter)

    2011-01-01

    textabstractAbstract. Economic growth in China has declined between 2008 and 2009. The global financial crisis of 2008/9 has shown a number of structural weaknesses in the Chinese economy, such as the functioning of its capital and labor markets and the substantial income differences between the dev

  20. Improving component interoperability and reusability with the java connection framework (JCF): overview and application to the ages-w environmental model

    Science.gov (United States)

    Environmental modeling framework (EMF) design goals are multi-dimensional and often include many aspects of general software framework development. Many functional capabilities offered by current EMFs are closely related to interoperability and reuse aspects. For example, an EMF needs to support dev...

  1. Inclusive business through partnerships

    NARCIS (Netherlands)

    R.J.M. van Tulder (Rob); A. Da Rosa (Andrea)

    2011-01-01

    textabstractAcademic and policy thought on economic growth and sustainable development in the 21st century represents a breach with traditional thinking. Traditional development approaches are getting replaced by new and more modern development thinking that adopts a contingency approach towards dev

  2. Maritime Security in West Africa

    DEFF Research Database (Denmark)

    Jacobsen, Katja; Nordby, Johannes Riber

    The problem of maritime insecurity in the Gulf of Guinea is not a new phenomenon, but a contemporary form of piracy in the Gulf of Guinea has arguably developed over the past 25 years to be more organized and violent. Besides the issue of how the phenomenon of piracy in the Gulf of Guinea has dev...

  3. Microfluidic platform with four orthogonal and overlapping gradients for soluble compound screening in regenerative medicine research

    NARCIS (Netherlands)

    Harink, Björn; Le Gac, Séverine; Barata, David; Blitterswijk, van Clemens; Habibovic, Pamela

    2015-01-01

    We present here a screening method based on a microfluidic platform, which can generate four orthogonal and overlapping concentration gradients of soluble compounds over a monolayer of cells, in combination with automated and in situ image analysis, for use in regenerative medicine research. The dev

  4. Experiment list: SRX444197 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ay || age=24 || body_site=Skin, arm || phenotype=Caucasian || cell_type=Dermal fibroblast || culture_collect...ion=NCSCR || dev_stage=Adult || sex=Male || tissue_type=Skin || label=AD04DF_LMNA

  5. Maternal rigidity in infancy and level of intelligence at school age in children born preterm

    NARCIS (Netherlands)

    Butcher, P.R.; Wijnberg-Williams, B.J; Hegemann, N; Stremmelaar, E.F; Schoemaker, M.M.; Van der Meere, J.J.; Bambang Oetomo, S

    2004-01-01

    Forty-four children who had been born preterm and their mothers participated in the follow-up study. At 3 and 14 months (corrected age) cognitive development was assessed using the BOS 2-30, the Dutch version of the Bayley Scales of Infant Development. The BOS yields measures of mental and motor dev

  6. SCALES: A System Level Tool for Conceptual Design of Nano- and Microsatellites

    NARCIS (Netherlands)

    Aas, C.; Zandbergen, B.T.C.; Hamann, R.J.; Gill, E.K.A.

    2009-01-01

    A satellite design tool has been developed offering systems engineers a fast way to analyze the feasibility of a particular design concept. The tool differs from available tools on the market in that it is specifically targeted at small satellites in the mass range of 1-50 kg, and with a limited dev

  7. Connexin43 confers Temozolomide resistance in human glioma cells by modulating the mitochondrial apoptosis pathway

    NARCIS (Netherlands)

    Gielen, P.R.; Aftab, Q.; Ma, N.; Chen, V.C.; Hong, X.; Lozinsky, S.; Naus, C.C.; Sin, W.C.

    2013-01-01

    Glioblastoma multiforme (GBM) is the most aggressive astrocytoma, and therapeutic options are generally limited to surgical resection, radiotherapy, and Temozolomide (TMZ) chemotherapy. TMZ is a DNA alkylating agent that causes DNA damage and induces cell death. Unfortunately, glioma cells often dev

  8. Improving adolescent sexual and reproductive health in Latin America: reflections from an International Congress

    NARCIS (Netherlands)

    Córdova Pozo, K.; Chandra-Mouli, V.; Decat, P.; Nelson, E.; de Meyer, S.; Jaruseviciene, L.; Vega, B.; Segura, Z.; Auquilla, N.; Hagens, A.; van Braeckel, D.; Michielsen, K.

    2015-01-01

    In February 2014, an international congress on Promoting Adolescent Sexual and Reproductive Health (ASRH) took place in Cuenca, Ecuador. Its objective was to share evidence on effective ASRH intervention projects and programs in Latin America, and to link this evidence to ASRH policy and program dev

  9. Strategies for Perceiving Facial Expressions in Adults with Autism Spectrum Disorder

    Science.gov (United States)

    Walsh, Jennifer A.; Vida, Mark D.; Rutherford, M. D.

    2014-01-01

    Rutherford and McIntosh (J Autism Dev Disord 37:187-196, 2007) demonstrated that individuals with autism spectrum disorder (ASD) are more tolerant than controls of exaggerated schematic facial expressions, suggesting that they may use an alternative strategy when processing emotional expressions. The current study was designed to test this finding…

  10. The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling

    NARCIS (Netherlands)

    Budry, L.; Balsalobre, A.; Gauthier, Y.; Khetchoumian, K.; L'Honore, A.; Vallette-Kasic, S.; Brue, T; Figarella-Branger, D.; Meij, B.P.; Drouin, J.

    2012-01-01

    Genes Dev. 2012 Oct 15;26(20):2299-310. doi: 10.1101/gad.200436.112. The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling. Budry L, Balsalobre A, Gauthier Y, Khetchoumian K, L'honoré A, Vallette S, Brue T, Figarella-Branger D, Meij B, Drou

  11. 76 FR 2688 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

    Science.gov (United States)

    2011-01-14

    ... From the Federal Register Online via the Government Publishing Office FEDERAL RESERVE SYSTEM... management consulting and employee benefits consulting services; (10) financing and investing in community... Governors of the Federal Reserve System, January 10, 2011. Robert deV. Frierson, Deputy Secretary of...

  12. Attenuated Salmonella typhimurium delivering DNA vaccine encoding duck enteritis virus UL24 induced systemic and mucosal immune responses and conferred good protection against challenge

    Directory of Open Access Journals (Sweden)

    Yu Xia

    2012-07-01

    Full Text Available Abstract Orally delivered DNA vaccines against duck enteritis virus (DEV were developed using live attenuated Salmonella typhimurium (SL7207 as a carrier and Escherichia coli heat labile enterotoxin B subunit (LTB as a mucosal adjuvant. DNA vaccine plasmids pVAX-UL24 and pVAX-LTB-UL24 were constructed and transformed into attenuated Salmonella typhimurium SL7207 resulting SL7207 (pVAX-UL24 and SL7207 (pVAX-LTB-UL24 respectively. After ducklings were orally inoculated with SL7207 (pVAX-UL24 or SL7207 (pVAX-LTB-UL24, the anti-DEV mucosal and systemic immune responses were recorded. To identify the optimum dose that confers maximum protection, we used different doses of the candidate vaccine SL7207 (pVAX-LTB-UL24 during oral immunization. The strongest mucosal and systemic immune responses developed in the SL7207 (pVAX-LTB-UL24 (1011 CFU immunized group. Accordingly, oral immunization of ducklings with SL7207 (pVAX-LTB-UL24 showed superior efficacy of protection (60-80% against a lethal DEV challenge (1000 LD50, compared with the limited survival rate (40% of ducklings immunized with SL7207 (pVAX-UL24. Our study suggests that the SL7207 (pVAX-LTB-UL24 can be a candidate DEV vaccine.

  13. Paraneoplastic pemphigus caused by an epithelioid leiomyosarcoma and associated with fatal respiratory failure

    NARCIS (Netherlands)

    van der Waal, RIF; Pas, HH; Nousari, HC; Schulten, EAJM; Jonkman, MF; Nieboer, C; Stoof, TJ; Starink, TM; Anhalt, GJ

    2000-01-01

    A patient is described who initially presented with pemphigus vulgaris, limited to the oral cavity, and weight loss. Although the various laboratory studies pointed to the diagnosis of paraneoplastic pemphigus (PNP), the underlying neoplasm was not detected until 6 months later, when the patient dev

  14. Continuity and discontinuity in community development theory

    NARCIS (Netherlands)

    J.B.W. Kuitenbrouwer (Joost)

    1973-01-01

    textabstractFew experienced fieldwerkers in community development who attend advanced training programmes have any expectation of acquiring a cut-and-dried solution that can be applied to problems in the field. Moreover, it is now wellknown that the advanced nations cannot provide the so-called dev

  15. Soft-islanding a group of houses through scheduling of CHP, PV and storage

    NARCIS (Netherlands)

    Perez, K.X.; Baldea, M.; Edgar, T.F.; Hoogsteen, G.; Leeuwen, van R.P.; Klauw, van der T.; Homan, B.; Fink, J.; Smit, G.J.M.

    2016-01-01

    In this paper we investigate the possibility of soft-islanding (near-autonomous operation) a group of houses from the electric power grid in the Netherlands. Energy balancing is possible through applying multi-mode smart grid scheduling for controllable energy generation, storage and consumption dev

  16. Metastatic Regulation of Differential Splicing of CD44

    Science.gov (United States)

    2001-08-01

    has been proposed that the accessory domains Minich et al., 1993; Evdokimova et al., 1995). YB-1 is an are responsible for sequence-independent RNA...enhancer. Genes Dev., 11, 1023-1036. Minich ,W.B., MaideburaI.P. and Ovchinnikov,L.P. (1993) Purification Received October 10, 2000; revised May 18, 2001

  17. Nanowire-based gas sensors

    NARCIS (Netherlands)

    Chen, X.; Wong, C.K.Y.; Yuan, C.A.; Zhang, G.

    2013-01-01

    Gas sensors fabricated with nanowires as the detecting elements are powerful due to their many improved characteristics such as high surface-to-volume ratios, ultrasensitivity, higher selectivity, low power consumption, and fast response. This paper gives an overview on the recent process of the dev

  18. Orchestrating Docker

    CERN Document Server

    Holla, Shrikrishna

    2015-01-01

    If you are a competent developer or DevOps with a good understanding of Linux filesystems but want to manage and orchestrate Docker services, images, and products using a multitude of techniques, then this book is for you. No prior knowledge of Docker or container virtualization is required.

  19. Amplifying applied game development and uptake

    NARCIS (Netherlands)

    Hollins, Paul; Westera, Wim; Manero, Borja

    2015-01-01

    The established (digital) leisure game industry is historically one dominated by large international hardware vendors (e.g. Sony, Microsoft and Nintendo), major publishers and supported by a complex network of development studios, distributors and retailers. New modes of digital distribution and dev

  20. Low recurrence rate of a two-layered closure repair for primary and recurrent midline incisional hernia without mesh

    NARCIS (Netherlands)

    A.H.M. Dur (Alfons); D. den Hartog (Dennis); W.E. Tuinebreijer (Wim); R.W. Kreis (Robert); J.F. Lange (Johan)

    2009-01-01

    textabstractBackground: Incisional hernia is a serious complication after abdominal surgery and occurs in 11-23% of laparotomies. Repair can be done, for instance, with a direct suture technique, but recurrence rates are high. Recent literature advises the use of mesh repair. In contrast to this dev

  1. Cardiovascular Adaptation to Stress

    Science.gov (United States)

    1979-05-01

    diiaaaniic pre’ssure and leart rrate. A new pa’a’.’.arc required fair cclasiai noted. Dillaaing~ pausa aiaal 465 I’,Iii £ittothe dev ice w as aga in c...aortic afferents lus intensities (rapidly conducting A fiber activa - Circulation Research. Vol. 37. July 1975 .-- J A AORTIC AFFERENT HEART RATE

  2. Understanding the Function of Tuberous Sclerosis Complex Genes in Neural Development: Roles in Synapse Assembly and Axon Guidance

    Science.gov (United States)

    2012-02-01

    through suppression of Wnt-beta-catenin signaling. Nat Genet 36: 1117–1121. 40. Radimerski T, Montagne J, Hemmings-Mieszczak M, Thomas G...and myoblast fusion. Genes Dev 8: 1787–1802. 43. Montagne J, Stewart MJ, Stocker H, Hafen E, Kozma SC, et al. (1999) Drosophila S6

  3. Mechanisms in manganese catalysed oxidation of alkenes with H2O2

    NARCIS (Netherlands)

    Saisaha, Pattama; de Boer, Johannes W.; Browne, Wesley R.

    2013-01-01

    The development of new catalytic systems for cis-dihydroxylation and epoxidation of alkenes, based on atom economic and environmentally friendly concepts, is a major contemporary challenge. In recent years, several systems based on manganese catalysts using H2O2 as the terminal oxidant have been dev

  4. Microbial detection and monitoring in advanced life support systems like the international space station

    NARCIS (Netherlands)

    van Tongeren, Sandra P.; Krooneman, Janneke; Raangs, Gerwin C.; Welling, Gjalt W.; Harmsen, Hermie J. M.

    2007-01-01

    Potentially pathogenic microbes and so-called technophiles may form a serious threat in advanced life support systems, such as the International Space Station (ISS). They not only pose a threat to the health of the crew, but also to the technical equipment and materials of the space station. The dev

  5. Microbial detection and monitoring in advanced life support systems like the International Space Station

    NARCIS (Netherlands)

    van Tongeren, Sandra P.; Krooneman, Janneke; Raangs, Gerwin C.; Welling, Gjalt W.; Harmsen, Hermie J. M.

    2006-01-01

    Potentially pathogenic microbes and so-called technophiles may form a serious threat in advanced life support systems, such as the International Space Station (ISS). They not only pose a threat to the health of the crew, but also to the technical equipment and materials of the space station. The dev

  6. Electrical Control, Read-out and Initialization of Single Electron Spins

    NARCIS (Netherlands)

    Shafiei, M.

    2013-01-01

    An electron, in addition to its electric charge, possesses a small magnetic moment, called spin. The spin of an electron can point parallel (spin-up) or antiparallel (spin-down) to the magnetic field. These two states are analogous to zero and one of the logical bit in current digital electronic dev

  7. Experiment list: SRX1428007 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available .7,0 ChIP Tfap2c in Mus musculus: TSC breed=not applicable || cultivar=not applicable || ecotype=not applicable... || isolate=not applicable || strain=not applicable || age=not applicable || dev_stage=not applicable ||

  8. Experiment list: SRX1428006 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 6,0 ChIP input control in Mus musculus: TSC breed=not applicable || cultivar=not applicable || ecotype=not applicable... || isolate=not applicable || strain=not applicable || age=not applicable || dev_stage=not applicable

  9. Experiment list: SRX1428005 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 1.3,0 ChIP Tfap2c in Mus musculus: 24 diff TSC breed=not applicable || cultivar=not applicable || ecotype=not applicable... || isolate=not applicable || strain=not applicable || age=not applicable || dev_stage=not applicable

  10. Experiment list: SRX1428009 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 39.7,7042 ChIP Elf5 in Mus musculus: f TSC breed=not applicable || cultivar=not applicable || ecotype=not applicable... || isolate=not applicable || strain=not applicable || age=not applicable || dev_stage=not applicable

  11. A Parent-Mediated Intervention that Targets Responsive Parental Behaviors Increases Attachment Behaviors in Children with ASD: Results from a Randomized Clinical Trial

    Science.gov (United States)

    Siller, Michael; Swanson, Meghan; Gerber, Alan; Hutman, Ted; Sigman, Marian

    2014-01-01

    The current study is a randomized clinical trial evaluating the efficacy of Focused Playtime Intervention (FPI) in a sample of 70 children with Autism Spectrum Disorder. This parent-mediated intervention has previously been shown to significantly increase responsive parental communication (Siller et al. in "J Autism Dev Disord"…

  12. The Role of Higher Level Adaptive Coding Mechanisms in the Development of Face Recognition

    Science.gov (United States)

    Pimperton, Hannah; Pellicano, Elizabeth; Jeffery, Linda; Rhodes, Gillian

    2009-01-01

    DevDevelopmental improvements in face identity recognition ability are widely documented, but the source of children's immaturity in face recognition remains unclear. Differences in the way in which children and adults visually represent faces might underlie immaturities in face recognition. Recent evidence of a face identity aftereffect (FIAE),…

  13. Modeling Ceramic Defeat Mechanisms and Variations in Ballistic Data

    Science.gov (United States)

    1998-05-01

    634050 RUSSIAN REPUBLIC 1 MILITARY RESEARCH INST ZAHORIE RESEARCH AND DEV. DEPT. M LAZAR EMPRESA NACIONAL SANTA 905 24 SENICA BARBARA SLOVAK REPUBLIC C...UNIVERSIDAD POLITICNICA DE J HAEBICEK MADRID 600 00 BRNO CIUDAD UNIVERSITARIA CZECH REPUBLIC E 28040 MADRID SPAIN 1 DEMEX CONSULTING ENG. A/S S MADSEN

  14. The Autism Diagnostic Observation Schedule, Module 4: Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (N = 93)

    Science.gov (United States)

    de Bildt, Annelies; Sytema, Sjoerd; Meffert, Harma; Bastiaansen, Jojanneke A. C. J.

    2016-01-01

    This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in "J Autism Dev Disord" 44(8):1996-2012, 2014) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the revised algorithm ASD cut-off…

  15. Importance of Being Nernst: Synaptic Activity and Functional Relevance in Stem Cell-derived Neurons

    Science.gov (United States)

    2015-07-26

    Zhang C. Induced multilineage differen- tiation of chicken embryonic germ cells via embryoid body formation. Stem Cells Dev 2010; 19: 195-202 [PMID...Khademhosseini A, Kim JH, Lee SH. Controlled-size embryoid body formation in concave microwell arrays. Biomaterials 2010; 31: 4296-4303 [PMID: 20206991 DOI

  16. An executable theory of multi-agent systems refinement

    NARCIS (Netherlands)

    Aştefănoaei, Lăcrămioara

    2011-01-01

    Complex applications such as incident management, social simulations, manufacturing applications, electronic auctions, e-institutions, and business to business applications are pervasive and important nowadays. Agent-oriented methodology is an advance in abstraction which can be used by software dev

  17. High throughput pyrogenic carbon (biochar) characterisation and quantification by liquid chromatography

    NARCIS (Netherlands)

    Cerqueira, W.V.; Rittl, T.F.; Novotny, E.H.; Pereira Netto, A.D.

    2015-01-01

    Characterisation and quantification of the carbonaceous polyaromatic structure of pyrogenic carbon (PyC) are of paramount importance to evaluate the role of PyC in soil carbon sequestration. A new method of rapid resolution liquid chromatography with UV diode array detection (RRLC-UV-DAD) was dev

  18. Characterization of African Bush Mango trees with emphasis on the differences between sweet and bitter trees in the Dahomey Gap (West Africa)

    NARCIS (Netherlands)

    Vihotogbe, R.

    2012-01-01

     African bush mango trees (ABMTs) are economically the most important species within the family of Irvingiaceae. They are priority trees producing non-timber forest products (NTFPs) and widely distributed in the humid lowland forests of West and Central Africa. To boost their production and dev

  19. MEANING : a roadmap to knowledge technologies

    NARCIS (Netherlands)

    Rigau, G.; Magnini, B.; Agirre, E.; Vossen, P.; Carroll, J.

    2002-01-01

    Knowledge Technologies need to extract knowledge from existing texts, which calls for advanced Human Language Technologies (HLT). Progress is being made in Natural Language Processing but there is still a long way towards Natural Language Understanding. An important step towards this goal is the dev

  20. Beyond ICT4D: new media research in Uganda

    NARCIS (Netherlands)

    Lovink, G.

    2011-01-01

    Beyond ICT4D: New Media Research in Uganda is a collection of ethnographic reports from diverse perspectives of those living at the other end of the African ICT pyramid. Crucially, these texts refocus on the so-called "ICT4D" debate away from the standard western lens, which depicts users in the dev

  1. Low-loss and programmable integrated photonic beamformer for electronically-steered broadband phased array antennas

    NARCIS (Netherlands)

    Zhuang, Leimeng; Marpaung, David; Burla, Maurizio; Roeloffzen, Chris; Beeker, Willem; Leinse, Arne; Dijk, van Paul

    2011-01-01

    Recently we have reported the dev electronically-steered Ku-band (10.7-12.75 G antenna system employing an integrated photonic beamformer, which is intended to be applied on high-speed transport vehicles for mobile reception of digital video broadcasting via satellite signals (1). Besides the advant

  2. A second-order boundary-fitted projection method for free-surface flow computations

    NARCIS (Netherlands)

    Yang, B.; Prosperetti, A.

    2006-01-01

    This paper describes a new approach to the high-fidelity simulation of axisymmetric free-surface flows. A boundary-fitted grid is coupled with a new projection method for the solution of the Navier–Stokes equations with second-order accuracy in space and time. Two variants of this new method are dev

  3. A New GIS-Nitrogen Trading Tool Concept to Minimize Reactive Nitrogen losses to the Environment

    Science.gov (United States)

    Nitrogen (N) is an essential element which is needed to maximize agricultural production and sustainability of worldwide agroecosystems. N losses to the environment are impacting water and air quality that has become an environmental concern for the future generations. It has led to the need for dev...

  4. Kuidas taasluua minevikku / David Vseviov

    Index Scriptorium Estoniae

    Vseviov, David, 1949-

    2012-01-01

    Mineviku kirjeldamisega seoses peab silmas pidama sellega kaasnevat ettemääratud piiratust. Ajaloolise tõe väide saab olla pädev vaid kõige üldisemates raamides, jättes detailides vabaduse kõikvõimalikeks oletusteks

  5. Brief Report: No Association between Premorbid Adjustment in Adult-Onset Schizophrenia and Genetic Variation in Dysbindin

    Science.gov (United States)

    Schirmbeck, Frederike; Georgi, Alexander; Strohmaier, Jana; Schmael, Christine; Boesshenz, Katja V.; Muhleisen, Thomas W.; Herms, Stefan; Hoffmann, Per; Jamra, Rami Abou; Schumacher, Johannes; Maier, Wolfgang; Propping, Peter; Nothen, Markus M.; Cichon, Sven; Rietschel, Marcella; Schulze, Thomas G.

    2008-01-01

    Whereas "Dysbindin" is considered a schizophrenia vulnerability gene, there is no consistency of findings. Phenotype refinement approaches may help to increase the genetic homogeneity and thus reconcile conflicting results. Premorbid adjustment (PMA) has been suggested to aid the phenotypic dissection. Gornick et al. ("J Autism Dev Disord"…

  6. A case study of Pedagogical Content Knowledge and faculty development in the Philippines

    NARCIS (Netherlands)

    van den Berg, E.; Cantrell, M.; Kool, R.; Kouwenhoven, W.

    2010-01-01

    The Science Teacher Education Project Southern Philippines (STEPS, 1996-2004) aimed at establishing a science and mathematics education centre and viable teacher education programmes. The most crucial component was faculty development. This involved the selection of faculty and then professional dev

  7. Resonance Energy Transfer-Based Molecular Switch Designed Using a Systematic Design Process Based on Monte Carlo Methods and Markov Chains

    Science.gov (United States)

    Rallapalli, Arjun

    A RET network consists of a network of photo-active molecules called chromophores that can participate in inter-molecular energy transfer called resonance energy transfer (RET). RET networks are used in a variety of applications including cryptographic devices, storage systems, light harvesting complexes, biological sensors, and molecular rulers. In this dissertation, we focus on creating a RET device called closed-diffusive exciton valve (C-DEV) in which the input to output transfer function is controlled by an external energy source, similar to a semiconductor transistor like the MOSFET. Due to their biocompatibility, molecular devices like the C-DEVs can be used to introduce computing power in biological, organic, and aqueous environments such as living cells. Furthermore, the underlying physics in RET devices are stochastic in nature, making them suitable for stochastic computing in which true random distribution generation is critical. In order to determine a valid configuration of chromophores for the C-DEV, we developed a systematic process based on user-guided design space pruning techniques and built-in simulation tools. We show that our C-DEV is 15x better than C-DEVs designed using ad hoc methods that rely on limited data from prior experiments. We also show ways in which the C-DEV can be improved further and how different varieties of C-DEVs can be combined to form more complex logic circuits. Moreover, the systematic design process can be used to search for valid chromophore network configurations for a variety of RET applications. We also describe a feasibility study for a technique used to control the orientation of chromophores attached to DNA. Being able to control the orientation can expand the design space for RET networks because it provides another parameter to tune their collective behavior. While results showed limited control over orientation, the analysis required the development of a mathematical model that can be used to determine the

  8. 鸭肠炎病毒强毒参考株在感染鸭体内的动态分布研究%Dynamic Distribution of Duck Enteritis Virus Standard Challenge Strain in Experimentally Infected Ducklings

    Institute of Scientific and Technical Information of China (English)

    文晶亮; 李俊平; 李启红; 李岭; 孙淼; 李慧姣; 杨承槐; 夏业才

    2014-01-01

    为研究鸭肠炎病毒( DEV)强毒株在感染鸭体内的动态分布规律,根据DEV的gD基因序列设计检测引物RT-gDF和RT-gDR,建立了特异性强、敏感性高、重复性好的检测DEV的SYBR GreenⅠ实时荧光定量PCR方法。应用已建立的方法,对DEV强毒参考株感染鸭的组织脏器进行了定量检测。结果显示,接种后6 h即可在所有受检组织中检测到DEV DNA,随着病程发展, DNA拷贝数持续升高,直至接种5 d后感染鸭全部死亡。其中结肠病毒DNA拷贝数为最高,达到1013.26 copies/g,法氏囊、肝脏和盲肠次之,约1012 copies/g。证实了DEV强毒对感染鸭的免疫器官、神经组织和消化系统均具有广泛的嗜性。%To explore the dynamic distribution of duck enteritis virus challenge standard strain ( DEV CSC ) in experimentally infected ducklings, the specific primers ( RT-gDF and RT-gDR) were designed according to the gene DEV gD, and the SYBR GreenⅠreal-time fluorescent quantitative PCR method for virulent strain with satisfaction of specificity, sensibility and repeatability was established. Copies of DEV DNA were quantified in the collected tissues by the fluorescent quantitative PCR method. In result, DEV CSC DNA were firstly detected in all the samples at six hours after inoculation and the DNA copies subsequently continued to rise till the death of all the ducklings infected with DEV CSC virulent strain five days after inoculation. The DNA copies of DEV CSC strain in colon(1013.26 copies/g) of dead ducklings was highest, and then came to bursa of Fabricius, caecum and liver, about 1012 copies/g. The results above comfirmed that the virulent strain CSC had broad tissue tropism on immune organs, nerve tissue and digestive system of infected ducks.

  9. Identification of legionella in clinical samples.

    Science.gov (United States)

    Jarraud, Sophie; Descours, Ghislaine; Ginevra, Christophe; Lina, Gerard; Etienne, Jerome

    2013-01-01

    Currently, several methods are used for the detection of Legionella in clinical samples, and these methods constitute part of the criteria for defining legionellosis cases. Urinary antigen detection is the first-line diagnostic test, although this test is limited to L. pneumophila serogroup 1 (Lp1) (Helbig et al., J Clin Microbiol 41:838-840, 2003). The use of molecular techniques can improve Legionaire's disease (LD) diagnosis by detecting other serogroups and species (Diederen et al., J Clin Microbiol 46:671-677, 2008). The isolation of Legionella strains from pulmonary samples by axenic culture is still required to perform further epidemiological investigations (Blyth et al., N S W Public Health Bull 20:157-161, 2009; Fields et al., Clin Microbiol Rev 15:506-526, 2002) but demonstrates various sensitivities. Amoebic coculture has been described as a method to recover Legionella from clinical culture-negative specimens (La Scola et al., J Clin Microbiol 39:365-366, 2001; Rowbotham, J Clin Pathol 36:978-986, 1983) and can be proposed for optimizing Legionella strain isolation from samples contaminated by oropharyngeal flora. Identification of Legionella isolates is based on serological characterization, genotypic methods (with sequencing of the mip gene as the standard method) and, more recently, the Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) method.This chapter is limited to the identification of Legionella in clinical samples; antibody detection in human serum will not be discussed.

  10. Randomised Clinical Efficacy Trial of Topiramate and Nitrazepam in Treatment of Infantile Spasms

    Directory of Open Access Journals (Sweden)

    Razieh FALLAH

    2014-01-01

    . A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: a report of the ILEA task force on classification and terminology. Epilepsia 2001; 42(6:796–803.Riikonen RS. Favourable prognostic factors with infantile spasms. Eur J Paediatr Neurol 2010;14(1:13-18.Lagae L, Verhelst H, Ceulemans B, De Meirleir L, Nassogne MC, De Borchgrave V, et al. Treatment and long term outcome in West syndrome: the clinical reality. A multicentre follow up study. Seizure 2010;19(3:159-64.Fois A. Infantile spasms: review of the literature and personal experience. Ital J Pediatr 2010;36:15-21.Jaseja H. Justification of vigabatrin administration in West syndrome patients? Warranting a re-consideration for improvement in their quality of life. Clin Neurol Neurosurg 2009;111(2:111-14.Hwang H, Kim KJ. New antiepileptic drugs in pediatric epilepsy. Brain Dev 2008,30(9;549–55.Mikaeloff Y, de Saint-Martin A, Mancini J, Peudenier S, Pedespan JM, Vallée L, et al. Topiramate: efficacy and tolerability in children according to epilepsy syndromes. Epilepsy Res 2003;53(3:225-32.Peltzer B, Alonso WD, Porter BE. Topiramate and Adrenal-Cortico-tropic Hormone as Initial Treatment of Infantile Spasms. J Child Neurol 2009;24(4:400-5.Zou LP, Lin Q, Qin J, Cai FC, Liu ZS, Mix E. Evaluation of open-label topiramate as primary or adjunctive therapy in infantile spasms. Clin Neuropharmacol 2008;31(2:86-92.Korinthenberg R, Schreiner A. Topiramate in children with west syndrome: a retrospective multicenter evaluation of 100 patients. J Child Neurol 2007;22(3:302-6.14. Kwon YS, Jun YH, Hong YJ, Son BK. Topiramate monotherapy in infantile spasm. Yonsei Med J 2006;47(4:498-504.Hosain SA, Merchant S, Solomon GE, Chutorian A. Topiramate for the treatment of infantile spasms. J Child Neurol 2006;21(1:17-9.Glauser TA, Clark PO, McGee K. Long-term response to topiramate in patients with West syndrome. Epilepsia 2000;41(Suppl. 1:S91-4.Albsoul-Younes AM, Salem HA, Ajlouni SF, Al-Safi SA

  11. Efficacy and Safety of Intravenous Sodium Valproate in Convulsive Status Epilepticus in Children in Shahid Sadoughi Hospital

    Directory of Open Access Journals (Sweden)

    Razieh FALLAH

    2012-06-01

    Full Text Available How to Cite this Article: Fallah R, Yadegari Y, Salmani Nodushan M. Efficacy and Safety of Intravenous Sodium Valproate in Convulsive Status Epilepticus in Children in Shahid Sadoughi Hospital. Iran. J. Child. Neurol 2012;6(2:39-44. Objective Status epilepticus (SE is the most common pediatric neurologic emergency with high mortality and morbidity. There is no consensus on the drug of choice in the treatment of children. The purpose of this study was to evaluate the clinical efficacy and safety of intravenous sodium valproate as a third-line drug in the treatment of generalized convulsive SE of children. Materials & Methods In a retrospective study, medical records of those children who were admitted to Shahid Sadoughi Hospital of Yazd due to refractory generalized convulsive SE and were treated by intravenous sodium valproate as a third-line drug from 2009 to 2011 were evaluated. Results Six girls and five boys with a mean age of 5.12 ± 1.2 years (range: 3 - 9.6 years were evaluated. Intravenous valproate was effective for cessation of seizures in seven patients (63.6 %. The mean dose of valproate for stopping seizures was 27.1 ± 1.4 mg/kg/day. Children whose seizures were controlled by sodium valproate were older than non- responsive children (mean± SD: 4.8 ± 1.2 years vs. 3.1 ± 0.43 years, p= 0.03 and they also had shorter ICU stay days (mean± SD: 2.6 ± 1.4 days vs. 5.6 ± 2.8 days, p= 0.01. Two children had mild and transient nausea and vomiting. None of them had cardiopulmonary or severe paraclinical side effects. Conclusion Intravenous sodium valproate may be used as an effective and safe third-line antiepileptic drug in the treatment of pediatric generalized convulsive status epilepticus.References Raj D, Gulati S, Lodha R. Status epilepticus. Indian J Pediatr 2011;78(2:219-26. Shearer P, Riviello J. Generalized convulsive status epilepticus in adults and children: treatment guidelines and protocols. Emerg Med Clin North Am 2011

  12. Adaptation and growth kinetics study of an Indian isolate of virulent duck enteritis virus in Vero cells.

    Science.gov (United States)

    Aravind, S; Kamble, Nitin M; Gaikwad, Satish S; Shukla, Sanjeev Kumar; Dey, Sohini; Mohan, C Madhan

    2015-01-01

    Duck virus enteritis, also known as duck plague, is a viral infection of ducks caused by duck enteritis virus (DEV). The control of the disease is mainly done by vaccination with chicken embryo adapted live virus that is known to be poorly immunogenic and elicits only partial protection. Further, the embryo propagated vaccine virus pose a threat of harboring other infectious agents. Seeing these limitations, the present study reports for the first time regarding propagation and adaptation of a virulent Indian isolate of duck enteritis virus in Vero cell line. In this study isolation of an outbreak virus from Kerala state was done in chicken embryo fibroblast cell culture (CEF). Then adapted the DEV isolate in the Vero cell line. The characteristic cytopathic effects (CPE) of clumping and fusion of Vero cells were observed starting from the 7th passage onwards. The presence of the virus and its multiplication in Vero cells was confirmed by detection of viral specific DNA and antigen by using polymerase chain reaction (PCR) and indirect immuno fluorescent assay (IIFA), respectively. PCR detection of DEV using self designed primers for US4 (gD) and UL30 (DNA Polymerase) gene has been reported for the in the present study. The kinetics of DEV in Vero cells revealed a maximum infectivity titer of 10(5.6) TCID 50/ml after 48hr of viral infection. Compared to chicken embryo adapted DVE vaccine virus, the Vero cell culture system is free from other infectious agents. So it will be a good candidate for cultivation and propagation of duck enteritis virus vaccine strain. Further research studies are suggested to explore the feasibility of utilizing this Vero cell culture adapted DEV isolate for developing an attenuated vaccine virus against duck virus enteritis.

  13. EXPRESSION OF EPIDERMAL GROWTH FACTOR, TRANSFORMING GROWTH FACTOR-a AND THEIR RECEPTOR IN HUMAN PITUITARY TUMORS

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Long

    2001-01-01

    [1]LIU Xu-wen, FU Pei-yu, GAO Zhi-xian. Expression of epidermal growth factor receptors in human glioma [J]. Chin J Neurosurgery 1998; 14:71.[2]Wong AJ, Ruppert JM, Bigner SH, et al. Structural alterations of the epidermal growth factor receptor gene in human gliomas [J]. Proc Natl Acad Sci USA 1992; 89:4309.[3]Webster J, Ham J, Bevan JS. Preliminary characterization of growth factors secreted by human pituitary tumors [J]. J Clin Endocrinol Metab 1991; 72:687.[4]Klibanski A. Nonsecreting pituitary tumors [J]. Endocrinol Metab Clin North Am 1987; 16:793.[5]LeRiche VK, Asa SL, Ezzat S. Epidermal growth factor and its receptor (EGF-R) in human pituitary adenomas: EGF-R correlates with tumor aggressiveness [J]. J Clin Endocrinol Metab 1996; 81:656.

  14. Dynamique temporelle de la sélection alimentaire chez l'abeille domestique (Apis mellifera L.) en paysage agricole

    OpenAIRE

    Requier, Fabrice; Odoux, Jean Francois; Tamic, Thierry; Feuillet, Dalila; Henry, Mickaël; Aupinel, Pierrick; DECOURTYE, Axel; Bretagnolle, Vincent

    2012-01-01

    Lors de la seconde moitié du XXème siècle, les paysages agricoles ont été profondément modifiés en raison de l'intensification de l'agriculture. Des perturbations dans tous les compartiments de la biodiversité ont été observées provoquant un déclin chez de nombreux taxons. L’abeille domestique (Apis mellifera L.) fait partie de ces espèces en déclin or elle fournit un service écosystémique de pollinisation indispensable pour les plantes sauvages et cultivées. La cause de ce déclin est multifa...

  15. Prolonged infusion of sedatives and analgesics in adult intensive care patients: A systematic review of pharmacokinetic data reporting and quality of evidence.

    Science.gov (United States)

    Tse, Andrew H W; Ling, Lowell; Joynt, Gavin M; Lee, Anna

    2017-03-01

    Although pharmacokinetic (PK) data for prolonged sedative and analgesic agents in intensive care unit (ICU) has been described, the number of publications in this important area appear relatively few, and PK data presented is not comprehensive. Known pathophysiological changes in critically ill patients result in altered drug PK when compared with non-critically ill patients. ClinPK Statement was recently developed to promote consistent reporting in PK studies, however, its applicability to ICU specific PK studies is unclear. In this systematic review, we assessed the overall ClinPK Statement compliance rate, determined the factors affecting compliance rate, graded the level of PK evidence and assessed the applicability of the ClinPK Statement to future ICU PK studies. Of the 33 included studies (n=2016), 22 (67%) were low evidence quality descriptive studies (Level 4). Included studies had a median compliance rate of 80% (IQR 66% to 86%) against the ClinPK Statement. Overall pooled compliance rate (78%, 95% CI 73% to 83%) was stable across time (P=0.38), with higher compliance rates found in studies fitting three compartments models (88%, P<0.01), two compartments models (83%, P<0.01) and one compartment models (77%, P=0.17) than studies fitting noncompartmental or unspecified models (69%) (P<0.01). Data unique to the interpretation of PK data in critically ill patients, such as illness severity (48%), organ dysfunction (36%) and renal replacement therapy use (32%), were infrequently reported. Discrepancy between the general compliance rate with ClinPK Statement and the under-reporting of ICU specific parameters suggests that the applicability of the ClinPK Statement to ICU PK studies may be limited in its current form.

  16. Neonatal Meningitis: Risk Factors, Causes, and Neurologic Complications

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    Nasrin KHALESSI

    2014-12-01

    . Characteristics of neonatal bacterial meningitis in a teaching hospital in Taiwan from 1984–1997. J. Microbiol. Immunol. Infect. 2000; 33: 100–4.Kavuncuoglu S, Gursoy S, Turel O, Aldemir E, Hosaf E. Neonatal bacterial meningitis in Turkey: epidemiology, risk factors, and prognosis J Infect Dev Ctries 2013; 7(2:073-081.Gerdes JS Diagnosis and management of bacterial infections in the neonate. Pediatr Clin Nam. 2004; 51: 939-959.Yikilmaz A and Taylor AG. Sonographic findings in bacterial meningitis in neonates and young infants. Pediatric Radiology 2008; 38: 129-137. 

  17. Comparison of Deflazacort and Prednisone in Duchenne Muscular Dystrophy

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    Parvaneh KARIMZADEH

    2012-03-01

    -Apr;10(2:138-51. Escolar DM, Leshner RT. Muscular dystrophies. In: Swaiman KF, Ashwal S, Ferriero DM. Pediatric Neurology. 4th ed. Philadelphia: Mosby; 2006. p. 1967-86. Sarnat HB, Menkes JH. Disease of the motor unit. In: Menkes JH, Sarnat HB, editors. Child Neurology. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. p. 984-9. Biggar WD, Politano L, Harris VA, Passamano L, Vajsar J, Alman B, et al. Deflazacort in duchenne muscular dystrophy: a comparison of two different protocols. Neuromuscul disord 2004 Sep;14(8-9:476-82. Radley HG, De Luca A, Lynch GS, Grounds MD. Duchenne muscular dystrophy: focus on pharmaceutical and nutritional interventions. Int J Biochem Cell Biol 2007;39(3:469-77.Biggar WD, Klamut HJ, Demacio PC, Stevens DJ. Duchenne muscular dystrophy: current knowledge, treatment and future prospects. Clin Orthop Relat Res 2002 Aug;401:88-106.Sohn RL, Gussoni E. Stem cell therapy for muscular dystrophy. Expert Opin Biol Ther 2004 Jan;4(1:1-9.Houde S, Filiatrault M, Fournier A, Dube J, D’Arcy S, Berube D et al. Deflazacort use in duchenne muscular dystrophy: an 8-year follow-up. Pediatr Neurol 2008 Mar;38(3:200-6.Bonifati MD, Ruzza G, Bonometto P, Berardinelli A, Gorni K, Orcesi K et al. A multicenter double-bind randomized trial of deflazacort versus prednisone in Duchenne muscular dystrophy: analysis after 2 years. Basic Appl Myol 2000;10:171-5.Reitter B. Deflazacort vs. prednisone in Duchenne muscular dystrophy: trends of an ongoing study. Brain Dev 1995;17 Suppl:39-43.Polgar G, Promadhat V. Standard values. In: pulmonary function testing in children: techniques and standards. Philadelphia: W.B. Saunders, 1971:102-3.Biggar WD, Gingras M, Febling DL, Harris VA, Steele CA. Deflazacort treatment of Duchenne muscular dystrophy. J Pediatr 2001 Jan;138(1:45-50. 

  18. Approach To The First Unprovoked Seizure- PART II

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    Mohammad GHOFRANI

    2013-11-01

    , adolescents and young adult. Seizure 1997;6:461-565.39.Berg AT, Shinnar S, Levy SR, Testa FM, et al. Early development of intractable epilepsy in children: A prospective study. Neurology 2001;56:1445-1452.40.Berg At, Shinnar S. The risk of seizure recurrence following a first unprovoked seizure: A quantitative review. Neurology 1991;41:955-972.41.Camfield PR, Camfield CS, Dooley JM, et al. Epilepsy after a first unprovoked seizure in childhood, Neurology 1985;35:1657-1660.42.Commission on epidemiology and prognosis. International League Against Epilepsy. Guidelines for epidemiologic studies on epilepsy. Epilepsia 1993;37:592-596.43.Annegers JF, Shirts SB, Hauser WA, et al. Risk of recurrence after an initial unprovoked seizure. Epilepsia 1986;27:43-50.44.Shinnar S, Berg AT, Moshe SL, Shinnar R. How long do new –onset seizures in children last? Ann Neurol 2001;49:659-664.45.Camfield P, Camfield C, Dooley J, et al. A randomized study of carbamazepine versus no medication after a first unprovoked seizure in childhood. Neurology 1989;39:851-852.46.Chandra B. First Seizure in adult: to treat or not to treat. Clin Neurol Neurosurg 1992;94:861-863.47.Musico M, Beghi E, Solari A, Viani F. Treatment of first Tonic-Clonic Seizure does not improve the prognosis of epilepsy. Neurology 1997;49:991-998.48.American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy (RE9537. Approach To The First Unprovoked Seizure-PART II. Pediatrics 1995;96:538-540.49.Yerby MS. Teratogenic effects of antiepileptic drugs: what do we advise patients? Epilepsia 1997;38-957-958.50.Vinig EP, Melits ED. Dorsen MM, et al. Psychologic and behavioral effects of antiepileptic drugs in children: A double-blind comparison between Phenobarbital and valproic acid. Pediatrics 1987;80: 165-174.51.Berg I, Butler A, Ellis M, Foster J. Psychiatric aspects of epilepsy in childhood treated with carbamazepine, phenytoin, or sodium valporate: a random trial. Dev Med Child Nerol 1993

  19. Early Life and Risk of Breast Cancer

    Science.gov (United States)

    2004-08-01

    adulthood in the 1958 British born cohort. Am J Clin Nutr 1997; 66:1094-101. 52. Kvale G, Heuch I. Menstrual factors and breast cancer risk. Cancer 1988; 62...Biomarkers Prey 2002;11: J Clin Nutr 1997;66:1094-101. 32. He Q Karlbergj. BMI in childhood and 207-10. 28. Kvale G, Heuch I. Menstrual factors and its...breast cancer among young U.S. women. Epidemiology 1997; 8(5):559-565. (76) Kvale G, Heuch I. Menstrual factors and breast cancer risk. Cancer 1988; 62(8

  20. The Genome Sequence of Bacillus cereus ATCC 10987 Reveals Metabolic Adaptations and a Large Plasmid Related to Bacillus anthracis pXO1

    Science.gov (United States)

    2004-01-01

    R.L. and Waites,K.B. (2003) Bacillus cereus bacteremia in a preterm neonate. J. Clin. Microbiol., 41, 3441±3444. 9. Ginsburg,A.S., Salazar,L.G., True... bacteremia and pneumonia due to Bacillus cereus . J. Clin. Microbiol., 35, 504±507. 12. Okinaka,R., Cloud,K., Hampton,O., Hoffmaster,A., Hill,K., Keim,P...The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1 David A. Rasko