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Sample records for climacteric stage women

  1. Integrative health care model for climacteric stage women: design of the intervention

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    Pérez-Cuevas Ricardo

    2011-02-01

    Full Text Available Abstract Background Climacteric stage women experience significant biological, psychological and social changes. With demographic changes being observed in the growing number of climacteric stage women in Mexico, it is important to improve their knowledge about the climacteric stage and its potential associated problems, encourage their participation in screening programs, and promote the acquisition of healthy lifestyles. At Mexican health care institutions the predominant health care model for climacteric stage women has a biomedical perspective. Medical doctors provide mostly curative services and have limited support from other health professionals. This study aims to design an integrative health care model (IHCM: bio-psycho-social, multidisciplinary and women-centered applicable in primary care services aimed at climacteric stage women. Methods/Design We present the design, inclusion criteria and detailed description of an IHCM. The IHCM consists of collaborative and coordinated provision of services by a health team, which is involves a family doctor, nurse, psychologist, and the woman herself. The health team promotes the empowerment of women through individual and group counseling on the climacteric stage and health related self-care. The intervention lasts three months followed by a three-month follow-up period to evaluate the effectiveness of the model. The effectiveness of the model will be evaluated through the following aspects: health-related quality of life (HR-QoL, empowerment, self-efficacy and knowledge regarding the climacteric stage and health-related self-care activities, use of screening services, and improvement in lifestyles (regular leisure time physical activity and healthy diet. Discussion Participation in preventive activities should be encouraged among women in Mexico. Designing and evaluating the effectiveness of an integrative health care model for women at the climacteric stage, based on the empowerment approach

  2. CLIMACTERIC SYMPTOMS AMONG WOMEN IN A RURAL AREA IN KERALA

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    Anil Bindhu

    2013-05-01

    Full Text Available ABSTRACT: Every woman who lives beyond 50 years goes through a period of transition from reproductive to non-reproductive stages of life. Meno pause is considered as a clinical marker of declining ovarian function. The common climacteric symptoms experienced by women during this period can be group into: vasomotor, somatic, psy chological and sexual complaints. The aim of the study was to compare the climacteric symptoms among rural women who attained menopause and those who did not attaine d menopause in the age group of 43-55 years. METHODS AND MATERIALS: A cross-sectional study design was conducted in a r ural area in Kerala. Data were collected from 320 women by interviewing with the help of a structured questionnaire consisting of a socio-demo graphic data, and the Greene’s Climacteric Scale. The Statistical Package for the Social Scien ces software Version 16.0 was used for statistical analyses. Mann Whitney U test was used to compare the total score of climacteric symptoms and each sub-scale symptom scores (psycholo gical, somatic, and sexual scores among women who attained and not attained menopause. The X² test was applied to compare the proportion of the different grades of symptoms bet ween the different menopausal statuses. The level P < 0.05 was considered as the cut-off va lue for significance RESULTS: The total Greene’s climacteric scale score (p: 0.001, the psyc hological subscale scores (p: 0.007, the somatic subscale scores (p : 0.022 , the vasomotor subscale scores (p: 0.011 and the sexual subscale scores (p: 0.001 were significantly higher in women who attained menopause compared to those who did not. CONCLUSION: The climacteric symptoms vary significantly between women who attained menopause and women who d id not attained menopause

  3. Instruments to study sleep disorders in climacteric women

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    Álvaro Monterrosa-Castro

    2016-07-01

    Full Text Available To identify the scales to assess sleep disorders applied to women with climacteric stage. Bibliographical research without intervention, the available information in scientific databases. Performed in PubMed, ScienceDirect, Scopus, Ebscohos OvidSP and Health Library. The words used in this article: insomnia, adjustment sleep disorder, questionnaires, studies and menopause. Publications of all types were included. Seven scales were identified: Insomnia Severity Index, Athens Insomnia Scale, Pittsburgh Quality of sleep Index, Epworth Sleepiness Scale, Jenkins Sleep Scale, Basic Nordic Sleep Questionnaire and The St Mary's Hospital Sleep Questionnaire. There are validated scales in multiple languages and considered appropriate for studying sleep disorders.

  4. Sexual satisfaction in couples in the male and female climacteric stage.

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    Salazar-Molina, Alide; Klijn, Tatiana Paravic; Delgado, Jaime Barrientos

    2015-02-01

    The objective was to describe the sexual life satisfaction of couples in the climacteric stage and determine whether there are differences between the perception of satisfaction and the sex life of each partner. We studied 142 couples obtained by stratified sampling of family health centers, Concepción, Chile. 66% of women and 84% of men reported being very or somewhat satisfied with their sex lives. Slight concordance was found between the responses of the partners in relation to satisfaction with their sexual life. Moreover, a slight degree of agreement was found between the sexual life satisfaction reported by women and their partners' perceptions of the women's sexual life satisfaction. Additionally, a slight degree of agreement was reported between the sexual life satisfaction reported by men and their partners' perceptions of the men's sexual life satisfaction. This study provides new information about Chilean couples in the climacteric stage in relation to self-reported sexual satisfaction and perceived satisfaction in couples.

  5. Sexual satisfaction in couples in the male and female climacteric stage

    OpenAIRE

    2015-01-01

    The objective was to describe the sexual life satisfaction of couples in the climacteric stage and determine whether there are differences between the perception of satisfaction and the sex life of each partner. We studied 142 couples obtained by stratified sampling of family health centers, Concepción, Chile. 66% of women and 84% of men reported being very or somewhat satisfied with their sex lives. Slight concordance was found between the responses of the partners in relation to satisfactio...

  6. Aromatherapy Massage Affects Menopausal Symptoms in Korean Climacteric Women: A Pilot-Controlled Clinical Trial

    OpenAIRE

    Myung-Haeng Hur; Yun Seok Yang; Myeong Soo Lee

    2008-01-01

    This study investigated the effects of aromatherapy massage on menopausal symptoms in Korean climacteric women. Kupperman's menopausal index was used to compare an experimental group of 25 climacteric women with a wait-listed control group of 27 climacteric women. Aromatherapy was applied topically to subjects in the experimental group in the form of massage on the abdomen, back and arms using lavender, rose geranium, rose and jasmine in almond and primrose oils once a week for 8 weeks (eight...

  7. ANTIHYPERTENSIVE THERAPY AND CLIMACTERIC DISORDERS IN POSTMENOPAUSAL WOMEN

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    A. A. Kirichenko

    2008-01-01

    Full Text Available Aim. To study efficacy and tolerability of antihypertensive therapy with enalapril (Berlipril®, Berlin-Chemie AG/Menarini Group and diltiazem (Altiazem® PP, Berlin-Chemie AG/Menarini Group in postmenopausal women with arterial hypertension (HT and climacteric disorders.Material and methods. 60 postmenopausal women (aged 56,8±3,9 y.o. with HT of 1-3 degrees were included into the study. They were split in two groups. Patients of the first group (30 people received enalapril (Berlipril® 20 mg/daily, patients of the second group (30 people – diltiazem (Altiazem® PP 180-360 mg/daily. Observation period was 6 months. Ambulatory blood pressure monitoring (ABPM was performed before treatment and after 3 weeks, 1, 3 and 6 months of therapy. Climacteric syndrome severity and urodynamic disorders was estimated as well as psychic status according to score of depression and anxiety.Results. Office and ambulance blood pressure decreased after 6 months of therapy in all patients of both groups. A number of complaints on headache and giddiness reduced significantly. Severity of climacteric syndrome also decreased. Enalapril (Berlipril® monotherapy and especially combined therapy with hydrochlorothiazide led to aggravation of urodinamic disorders. On the contrary both monotherapy with diltiazem (Altiazem® PP or its combination with hydrochlorothiazide had positive effect on urodinamics. Both therapies reduced depression and anxiety levels significantly.Conclusion. All spectrum of pharmacology effects should be taken into account during antihypertensive therapy of patients with climacteric disorders.

  8. Sexual satisfaction in couples in the male and female climacteric stage

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    Alide Salazar-Molina

    2015-02-01

    Full Text Available The objective was to describe the sexual life satisfaction of couples in the climacteric stage and determine whether there are differences between the perception of satisfaction and the sex life of each partner. We studied 142 couples obtained by stratified sampling of family health centers, Concepción, Chile. 66% of women and 84% of men reported being very or somewhat satisfied with their sex lives. Slight concordance was found between the responses of the partners in relation to satisfaction with their sexual life. Moreover, a slight degree of agreement was found between the sexual life satisfaction reported by women and their partners' perceptions of the women's sexual life satisfaction. Additionally, a slight degree of agreement was reported between the sexual life satisfaction reported by men and their partners' perceptions of the men's sexual life satisfaction. This study provides new information about Chilean couples in the climacteric stage in relation to self-reported sexual satisfaction and perceived satisfaction in couples.

  9. Suan Zao Ren Tang as an Original Treatment for Sleep Difficulty in Climacteric Women: A Prospective Clinical Observation

    OpenAIRE

    Chia-Hao Yeh; Arnold, Christof K.; Yen-Hui Chen; Jung-Nein Lai

    2011-01-01

    Little scientific evidence supports the efficacy of herbal medicines in the treatment of women with sleep difficulty during the climacteric period. The purpose of this study is to evaluate the efficacy and safety of Suan Zao Ren Tang (SZRT) in reducing the impact of sleep disturbance on climacteric women, as measured by Pittsburg sleep quality index (PSQI) and the World Health Organization quality of life (WHOQOL). Sixty-seven climacteric women with sleep difficulty intending to treat receive...

  10. [The relation between dysmenorrhea and hot flash in a group of women in climacteric].

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    Andreassi, S; Tesseri, E

    1992-01-01

    Hot flushes in climacteric age can cause noticeable discomfort to those who have them. This functional disturbance confirms the strong relationship between the gonadic steroids and the central neurotransmitters. These complex mechanisms which control reproductive functions limit our knowledge of the pathogenesis of hot flushes. The possible intervention of prostaglandins in the rising of this disturbance and their participation in dismenorrhea have raised the hypothesis that the prostaglandins may be the common denominator in the development of dysmenorrhea in fertile age women and of hot flushes in climacteric age women. Under this context, we examined a number of women in menopause to determine if they suffered with dysmenorrhea in fertile age.

  11. Aromatherapy Massage Affects Menopausal Symptoms in Korean Climacteric Women: A Pilot-Controlled Clinical Trial

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    Myung-Haeng Hur

    2008-01-01

    Full Text Available This study investigated the effects of aromatherapy massage on menopausal symptoms in Korean climacteric women. Kupperman's menopausal index was used to compare an experimental group of 25 climacteric women with a wait-listed control group of 27 climacteric women. Aromatherapy was applied topically to subjects in the experimental group in the form of massage on the abdomen, back and arms using lavender, rose geranium, rose and jasmine in almond and primrose oils once a week for 8 weeks (eight times in total. The experimental group reported a significantly lower total menopausal index than wait-listed controls (P < 0.05. There were also significant intergroup differences in subcategories such as vasomotor, melancholia, arthralgia and myalgia (all P < 0.05. These findings suggest that aromatherapy massage may be an effective treatment of menopausal symptoms such as hot flushes, depression and pain in climacteric women. However, it could not be verified whether the positive effects were from the aromatherapy, the massage or both. Further rigorous studies should be done with more objective measures.

  12. Climacteric complaints among very low-income women from a tropical region of Brazil

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    Sebastião Freitas de Medeiros

    Full Text Available CONTEXT AND OBJECTIVE: Climacteric symptoms may vary between different countries and cultures. Socioeconomic factors and climate may be implicated. The aim of this study was to identify climacteric symptomatology among very low-income Brazilian women, living in a hot and humid region. DESIGN AND SETTING: This cross-sectional population-based study was conducted in Cuiabá, at Júlio Müller University Hospital, a tertiary institution. METHODS: The study enrolled 354 climacteric women. The variables analyzed were social class, symptomatology and abnormal concurrent conditions. The study was approved by the hospital's research ethics committee. RESULTS: Sixty-five percent of the participants (232/354 were very poor and had had little schooling. The number of symptoms per woman was 8.0 ± 5.7. Hot flushes, nervousness, forgetfulness and fatigue were each found in nearly 60.0%. Tearfulness, depression, melancholy and insomnia were also frequent. Sexual problems were reported by 25%. The most relevant concurrent abnormal conditions reported were hypertension (33.9%, obesity (26.5%, arthritis/arthrosis (15.0% and diabetes mellitus (9.6%. Hot flushes were associated with tearfulness, nervousness and forgetfulness. CONCLUSION: Brazilian climacteric women of low income and low schooling present multiple symptoms. Vasomotor and psychosexual symptoms were the most prevalent disorders. Hot flushes were associated with nervousness, forgetfulness and tearfulness.

  13. Cyto-histologic evaluation of the endometrium in climacteric women at risk for endometrial carcinoma.

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    de Aloysio, D; Rocca, G; Miliffi, L

    1986-08-31

    The authors evaluated the diagnostic effectiveness of a triple specimen technique (cyto-histologic) performed by the Perma device. The incidence of endometrial hyperplasia (according to Dallenbach-Hellweg's classification) was estimated in 254 climacteric women selected from outpatients who come spontaneously to the Menopause Clinic of the Obstetrics and Gynecology Department (Bologna University). The selection criterion was the evidence of risk factors for endometrial carcinoma, climacteric bleedings (obesity, late menopause, high blood pressure, diabetes), or endometriotropic estrogen therapy in the postmenopause. Results showed that the cyto-histologic sampling is most useful for diagnosing endometrial hyperplasia and early carcinoma (diagnostic effectiveness: 89.0-93.8%). Also, endometrial hyperplasia was found to have a significant incidence in the group we examined. This incidence was highest in women with climacteric bleedings, secondly in women using high-dose estrogens, and thirdly in women with risk factors for endometrial carcinoma. When evaluating the different kinds of endometrial hyperplasia, we never found adenomatous hyperplasia in women on estrogen therapy. Affinity between histologic and cytologic classes was around 50% in endometrial hyperplasia and 100% in early carcinoma. This emphasizes that both samplings are needed to perform an accurate diagnosis.

  14. Social representations elaborated by nurses about climacteric women in primary health care

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    Smithanny Barros da Silva

    2016-01-01

    Full Text Available Objective : to understand the social representations elaborated by nurses from the family health strategy concerning the assistance to climacteric women. Methods : qualitative research conducted with 28 nurses. One adopted the reference of procedural approach of the theory of social representations. The interviews were recorded and transcribed completely and processed by the Software of Lexical Analysis of co-occurrence in simple statements of a text, version 4.7. Results: nurses recognize the menopause as a phase of women’s life that needs to be assisted in its entirety, however, they showed difficulty in helping them, as they just carry out the cytological examination collection, request laboratory tests and forward them to a doctor. Conclusion: the climacteric period is a multifaceted phenomenon and the assistance to those people should be systematized from a qualified listening, in an approach that respects its uniqueness and autonomy.

  15. Suan zao ren tang as an original treatment for sleep difficulty in climacteric women: a prospective clinical observation.

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    Yeh, Chia-Hao; Arnold, Christof K; Chen, Yen-Hui; Lai, Jung-Nein

    2011-01-01

    Little scientific evidence supports the efficacy of herbal medicines in the treatment of women with sleep difficulty during the climacteric period. The purpose of this study is to evaluate the efficacy and safety of Suan Zao Ren Tang (SZRT) in reducing the impact of sleep disturbance on climacteric women, as measured by Pittsburg sleep quality index (PSQI) and the World Health Organization quality of life (WHOQOL). Sixty-seven climacteric women with sleep difficulty intending to treat received SZRT at a rate of 4.0 g, thrice daily for four weeks (MRS < 16, n = 34; MRS ≥ 16, n = 33). After taking into account potential confounding factors, the mean PSQI total scores had fallen from 13.0 (±2.9) to 9.0 (±3.2) (95% confidence interval -4.93, -3.10). Further analyses showed that SZRT produced superior benefit of daytime dysfunction in women with severe menopausal symptoms (MRS ≥ 16). There were three of the withdrawals involved treatment-related adverse events (stomachache, diarrhea, and dizziness). Excluding women with a past history of stomachache, diarrhea, or dizziness, four weeks of therapy with SZRT appears to be a relatively safe and effective short-term therapeutic option in improving daytime function of climacteric women with poor sleep quality.

  16. Suan Zao Ren Tang as an Original Treatment for Sleep Difficulty in Climacteric Women: A Prospective Clinical Observation

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    Chia-Hao Yeh

    2011-01-01

    Full Text Available Little scientific evidence supports the efficacy of herbal medicines in the treatment of women with sleep difficulty during the climacteric period. The purpose of this study is to evaluate the efficacy and safety of Suan Zao Ren Tang (SZRT in reducing the impact of sleep disturbance on climacteric women, as measured by Pittsburg sleep quality index (PSQI and the World Health Organization quality of life (WHOQOL. Sixty-seven climacteric women with sleep difficulty intending to treat received SZRT at a rate of 4.0 g, thrice daily for four weeks (MRS<16, n=34; MRS≥16, n=33. After taking into account potential confounding factors, the mean PSQI total scores had fallen from 13.0 (±2.9 to 9.0 (±3.2 (95% confidence interval −4.93, −3.10. Further analyses showed that SZRT produced superior benefit of daytime dysfunction in women with severe menopausal symptoms (MRS≥16. There were three of the withdrawals involved treatment-related adverse events (stomachache, diarrhea, and dizziness. Excluding women with a past history of stomachache, diarrhea, or dizziness, four weeks of therapy with SZRT appears to be a relatively safe and effective short-term therapeutic option in improving daytime function of climacteric women with poor sleep quality.

  17. The Effect of Melatonin on Climacteric Symptoms in Menopausal Women; A Double-Blind, Randomized Controlled, Clinical Trial.

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    Nehleh Parandavar

    2014-10-01

    Full Text Available Menopause is one of the most critical periods of woman's life. With reducing of ovarian estrogen; women are more prone to psychological and physical symptoms. The present study aimed to investigate the effect of melatonin on the climacteric symptoms.The present double blind, placebo randomized controlled clinical trial was conducted on 240 menopausal women (40 - 60 years old referring to the gynecology clinics of Shiraz University of Medical Sciences (January - November 2012. The participants were randomly divided into two groups through sortition. Demographic characteristics, Goldberg's general health questionnaire (GHQ, Greene Climacteric Scale and level of Follicle Stimulating Hormone (FSH were determined for both groups before the intervention. The intervention group received one 3mg melatonin tablet each night for 3 months and the control group received the placebo in the same period. Changes of climacteric symptoms and drug complications were measured 1, 2 and 3 months after the intervention.We analyzed the data of 99 postmenopausal women in the intervention group and 101 postmenopausal women in the control group. In the melatonin group, the climacteric symptoms score decreased from 35.73+11.6 to 17.09+10.22 during the 3-month study period and regardless of time, a significant difference was observed between the two groups (P<0.001. In addition, a significant difference was found between the two groups regarding various dimensions of the climacteric symptoms over time (P<0.001. No significant difference was found regarding side effects between the two groups (P= 0.135.The study findings showed that using melatonin improved the climacteric symptoms.

  18. The effectiveness of planned health education given to climacteric women on menopausal symptoms, menopausal attitude and health behaviors

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    Gülbu Tortumluoğlu

    2006-11-01

    Full Text Available Objective: The research was made to assign the effect of planned health education given to climacteric women on menopausal symptoms, menopausal attitude and health behaviors. Methods: The research was carried between January 2002-February 2003 in the district of Abdurrahman Gazi Primary Health department which lies in the borders of metropolitan municipality of Erzurum. 2761 climacteric women between the age of 40-60 formed the population of the research. In sample selection, because of knowing the frequency of event and the number of individuals in the population; the formula of, n=N . t2 . pq / y2 .(N-1 + t2 . pq was used and samples are assigned as 337. Afterresearch problem had been assigned on 337 women, the research was made control group with pretest-posttest of quasi experimental design on 100 women who were selected proper to the aim of the research, 50 of which was experiment, the rest was control group. But 87 women 44 of which was control, 434 of which was experiment group completed the research. Results: According to the research results, after planned health education given by the researcher, decrease in common menopausal symptoms and increase in point averages of menopausal attitude (t=4.697, p=.000 and health promotion life style behaviors (t=7.127, p=.000 were determined. Conclusion: After planned health education given to the women in climacteric period, positive health behaviors can be developed so as to make women live a more peaceful life. According to these result, it can be suggested to health professionals to mind education programs about climacteric period.

  19. Succinate-based preparation alleviates manifestations of the climacteric syndrome in women.

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    Peskov, A B; Maevskii, E I; Uchitel', M L; Sakharova, N Yu; Vize-Khripunova, M A

    2005-09-01

    Clinical placebo-controlled study of Enerlit-Clima (bioactive succinate-based food additive) a showed positive effect of the preparation on general clinical and psychoemotional manifestations of the climacteric syndrome. A trend to an increase in estradiol level in early pathological climacteric and normalization of the endometrial status were observed.

  20. Conditions of life and climacteric in middle aged women in a health area of Sancti Spiritus.

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    Silvia Esther de la Torre Cárdenas

    2012-09-01

    Full Text Available A climacteric is one of the difficult steps in women life in which a particular attention is needed by the doctor and a big comprehension from the social point of view. A retrospective descriptive study was made in the South Area Polyclinic of Sancti Spiritus Municipality, period january – april 2007, with a female population having between 45 -59 years of age from 8 family medical clinics, 4 belonging to the urban area and 4 to the rural one (191 in total, including all which referred to present any disorder with the menstrual cycle due to excess or defect in the 6 months previous to interview (165 in total with the objective to evaluate the relation between conditions of life and the frequency; criticality and morbidity associated with menopause syndrome. Life conditions, kind of work, kind of activity carried out and associated pathologies are the factors that according to the study influence in frequency, criticality and morbidity associated with menopause syndrome in middle aged women and the overhead given by the conditioning of gender, favored the appearance of symptoms such as hot, depression, anxiety, tachycardia and vaginal dryness.

  1. Changes of Plasma Concentration of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in climacteric women with hot flushes

    Institute of Scientific and Technical Information of China (English)

    Chen Ya-qiong; Wu Wei-guang

    2007-01-01

    Objective: To investigate the relationship between the changes of serotonin metabolism and the hot flushes in climacteric women.Methods.Ninety eight climacteric women, aged 40-60, were enrolled and divided into 4 groups: Group A: 20 cases of early menopausal transition.Group B: 26 cases of late menopausal transition, with skip of periods 3-12 months.Group C: 28 cases of early postmenopause (1-3 yrs).Group D: 24 cases of late postmenopause(>3-6 yrs).Twelve normal women of reproductive age (24±3yrs) were served as young controls.Fifty two postmenopausal women were subdivided into 3 groups according to the presence or the absence of hot flushes: (1) postmenopausal controls without hot flushz 17 cases, (2) mild hot flushes group: 20 eases,fewer≤5 times/d, (3) severe hot flushes group: 15 cases, more than 5 times/d.Plasma concentrations of tryptophan (TP), 5-hydroxytryptophane (5-HTP), 5-hydroxytryptamine (5-HT or serotonin), 5-hydroxyindoleacetic acid (5-HIAA) and luteinizing hormone (LH) were measured in all participants by high pressure liquid chromatography-fluorescence spectrophotometer (HPLC-FS).The relationship between serotonin metabolic parameters and menopause, hot flushes were analysed.Results: (1) Mean 5-HT and 5-HIAA concentrations in plasma were significantly higher in climacteric women than those in young controls, especially in Group B.Mean 5-HTP and 5-HT levels were higher and 5-HIAA lower in Group D as compared with those of young controls.(2) Plasma 5-HT levels was positively correlated to luteinizing hormone concentration in postmenopansal women (P<0.01).(3) In the mild hot flushes group, only plasma 5-HTP levels were significantly higher than that in the non-hot flushes group.In severe hot flushes group,plasma 5-HT and 5-HTP contents were significantly higher and 5-HIAA/5-HT ratio lower than those in the non-hotflushes groups.Conclusion: The results suggest that the catabolic disorder of serotonin maybe involve in the underling mechanism of

  2. Mulher no climatério: reflexões sobre desejo sexual, beleza e feminilidade Women in the climacteric: reflections on sexual desire, beauty and femininity

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    Cecília Nogueira Valença

    2010-06-01

    Full Text Available O climatério é um período abrangente da vida feminina, caracterizado por alterações metabólicas e hormonais que trazem mudanças envolvendo o contexto psicossocial. Tendo como referência as alterações de sexualidade vivenciadas no climatério, este trabalho tem por objetivo refletir sobre desejo sexual, beleza e feminilidade da mulher nessa fase. A metodologia adotada consistiu em estudo bibliográfico, em livros e artigos publicados, entre 1999 e 2009. A exigência exacerbada pela beleza eterna e jovialidade é agravada no climatério, no qual o corpo feminino não tem o mesmo vigor físico pelas alterações decorrentes do envelhecimento. A mulher climatérica vive o mito da perda do desejo sexual, todavia, continua a sentir prazer, não devendo deixar de manifestar amor e sexualidade. A visão social estereotipada sobre o papel da mulher (esposa e mãe pode interferir negativamente na visão das mulheres sobre si mesmas e no seu relacionamento com as pessoas e o mundo. Nesse sentido, é importante que as mulheres tenham acesso à informação em saúde para a compreensão das mudanças do período de climatério/menopausa, contemplando e ressignificando tal fase como integrante de seus ciclos de vida e não como sinônimo de velhice, improdutividade e fim da sexualidade.The climacteric is a long period of a woman's life, characterized by metabolic and hormonal alterations that bring changes involving the psychosocial context. Having as reference the sexuality alterations experienced in the climacteric, this literature review aims to reflect on women's sexual desire, beauty and femininity in this phase. The methodology involved a bibliographic study of papers and books published between 1999 and 2009. The exaggerated need of eternal beauty and youth is aggravated in the climacteric, when the female body does not have the same physical vigor due to alterations deriving from aging. The climacteric woman lives the myth of loss of sexual

  3. Estado nutricional e qualidade de vida da mulher climatérica Nutritional status and quality of life of climacteric women

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    Carin Weirich Gallon

    2012-04-01

    Full Text Available OBJETIVO: Associar a qualidade de vida com o estado nutricional da mulher climatérica. MÉTODOS: Trata-se de estudo transversal, no qual foi incluída uma amostra com 200 mulheres climatéricas, de 40 a 65 anos, que responderam a um Recordatório Alimentar de 24 horas e questões sobre fatores socioeconômicos, história clínica atual, pregressa e familiar. Para a avaliação antropométrica, foram utilizados índice de massa corpórea (IMC, circunferência da cintura (CC e relação cintura/quadril. Para avaliação da qualidade de vida, foi aplicado o MRS-menopause rating scale. RESULTADOS: A média do IMC e da CC foi de 30,1 kg/m² (obesidade grau 1 e 99 cm (risco muito aumentado para doença cardiovascular, respectivamente. Constatou-se consumo aumentado de proteínas e diminuído de fibras, cálcio e vitamina D. A comorbidade mais prevalente foi a hipertensão arterial, 48,5% faziam uso de medicação para doenças cardiovasculares e 23%, de medicações antidepressivas. Quanto à qualidade de vida, foram encontrados resultados significativos relacionados ao IMC, como também à pressão arterial. CONCLUSÕES: Uma intervenção nutricional visando corrigir ou melhorar o consumo alimentar e o perfil antropométrico poderá resultar em benefícios relativos à saúde da mulher climatérica. A prevalência de obesidade, associada com pior qualidade de vida e morbimortalidade, reforça a necessidade de existir um programa de reeducação alimentar no climatério.PURPOSE: To associate the quality of life with the nutritional status of climacteric women. METHODS: This was a cross-sectional study on a sample of 200 climacteric women aged 40 to 65 years who responded to a 24-hour food recall and to questions about socioeconomic factors and current, previous and family medical history. Body mass index (BMI, waist circumference (WC and waist-hip ratio were used for anthropometric evaluation. To assess the quality of life, we applied the MRS

  4. Clinical Observation on Treatment of Women Climacteric Insomnia by Plum-Blossom Needle: A Report of 50 Cases

    Institute of Scientific and Technical Information of China (English)

    LI Xiao-qing; LI Nai-rong

    2004-01-01

    To observe the treatment of 50 female patients with climacteric insomnia by plum-blossom needle therapy. According to differentiation of symptoms and signs the head, back, belly and other location were tapping. Besides 50 patients were treated with Western medicine as a control group. The result showed the immediate and long-term effect in plum-blossom needle group was better than that in control group (P<0.01).%梅花针叩刺头部,背部和腹部,并根据辨证配穴治疗更年期综合征以失眠为主症的患者50例,并与西药治疗50例相对照,梅花针组近期疗效和远期疗效均好于对照组(P<0.01).

  5. Procura de serviço médico por mulheres climatéricas brasileiras Climacteric women seeking medical care, Brazil

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    Adriana Orcesi Pedro

    2002-08-01

    Full Text Available OBJETIVO: Identificar as causas e os fatores relacionados à procura de serviço médico por mulheres climatéricas. MÉTODOS: Realizou-se estudo descritivo e exploratório de corte transversal, de base populacional. Selecionaram-se, por meio de amostragem por conglomerado, 456 mulheres residentes no município de Campinas, SP, na faixa etária entre 45 e 60 anos de idade. Os dados sobre os motivos de procura dos serviços médicos foram coletados por meio de entrevistas domiciliares, com questionário estruturado e pré-testado. A análise dos dados foi realizada pelo teste qui-quadrado, pelo coeficiente de Cramer e pela análise de regressão linear múltipla. RESULTADOS: Aproximadamente 80% das mulheres climatéricas procuraram atenção médica por causa da irregularidade menstrual e dos sintomas climatéricos. Mulheres com companheiro, em terapia de reposição hormonal e com maior intensidade dos sintomas psicológicos foram as que mais procuraram atenção médica. A principal razão para a não-procura foi a mulher considerar que a queixa não merecia atenção médica. CONCLUSÕES: A procura de serviço médico por queixas relacionadas ao climatério foi alta, porém um porcentual significativo de mulheres não procurou atenção médica por considerar a sintomatologia natural.OBJECTIVE: To study the causes and factors associated with climacteric women seeking medical care. METHODS: A descriptive exploratory cross-sectional population-based study was carried out. Subjects were 456 women aged 45 to 60 years resident in a metropolitan area of Southeastern, Brazil, selected through area cluster sampling. Data were collected through home interviews using a structured, pre-tested questionnaire. Statistical analysis were performed using Chi-square test, Cramer's coefficient and logistic multiple regression. RESULTS: About 80% sought medical care due to menstrual irregularities and climacteric symptoms. The main factors associated with women

  6. Non-climacteric ripening and sorbitol homeostasis in plum fruits.

    Science.gov (United States)

    Kim, Ho-Youn; Farcuh, Macarena; Cohen, Yuval; Crisosto, Carlos; Sadka, Avi; Blumwald, Eduardo

    2015-02-01

    During ripening fruits undergo several physiological and biochemical modifications that influence quality-related properties, such as texture, color, aroma and taste. We studied the differences in ethylene and sugar metabolism between two genetically related Japanese plum cultivars with contrasting ripening behaviors. 'Santa Rosa' (SR) behaved as a typical climacteric fruit, while the bud sport mutant 'Sweet Miriam' (SM) displayed a non-climacteric ripening pattern. SM fruit displayed a delayed ripening that lasted 120 days longer than that of the climacteric fruit. At the full-ripe stage, both cultivars reached similar final size and weight but the non-climacteric fruits were firmer than the climacteric fruits. Fully ripe non-climacteric plum fruits, showed an accumulation of sorbitol that was 2.5 times higher than that of climacteric fruits, and the increase in sorbitol were also paralleled to an increase in sucrose catabolism. These changes were highly correlated with decreased activity and expression of NAD(+)-dependent sorbitol dehydrogenase and sorbitol oxidase and increased sorbitol-6-phosphate dehydrogenase activity, suggesting an enhanced sorbitol synthesis in non-climacteric fruits.

  7. Study on nursing intervention for climacteric women in depression status%更年期妇女抑郁状态的护理干预研究

    Institute of Scientific and Technical Information of China (English)

    曹继艳

    2009-01-01

    目的 探讨更年期妇女抑郁状态的护理干预效果.方法 将80例更年期抑郁妇女随机分对照组和观察组,每组40例.观察组实施综合护理干预,对照组不予护理干预.采用抑郁自评量表(SDS)、自评症状量表(SSCL-90)、社会支持评定量表(SSRS)对其效果进行评价.结果 干预前两组SDS、SSRS、SSCL-90得分差异无显著性;干预后两组SDS、SSRS、SSCL-90的得分与干预前及组间比较,差异有显著性(P<0.01).结论 实施护理干预明显改善患者的抑郁状态,有效地提高患者的生活质量,减轻了社会和家庭的负担,体现了人本关怀的理念.%Objective To research the effect of nursing intervention for climacteric women in depression status. Methods 80 depressed climacteric women were randomly divided into control and observation groups. The observation group was given integration nursing intervention. The Self-rating Depressive Scale (SDS), Symptom Checklist 90 (SCL-90), Social Support Bating Scale (SSBS) were used to evaluate the treatment effective-hess. Results Before nursing intervention, the scores of SDS, SSRS, SCL-90 between two groups werenot dif-ferent;and the scores of SDS, SSRS, SCL - 90 were significant difference after the nursing intervention (P <0.01 ). Conclusions The treatment with nursing intervention can improve the depressive state of patients, uplift patients'life quality, lighten the burden of society and patients'familles, and embody the idea of people oriented.

  8. Sexual dysfunction in climacteric women of African descent from the Colombian Caribbean region = Disfunción sexual en mujeres climatéricas afrodescendientes del Caribe Colombiano

    Directory of Open Access Journals (Sweden)

    Monterrosa Castro, Alvaro De Jesus

    2014-01-01

    Full Text Available Introduction: After the United States and Brazil, Colombia is the third American country with the greatest population of African descent. Objective: To estimate the prevalence of sexual dysfunction (SD in climacteric women of African descent. Methods: Cross sectional study carried out with the Female Sexual Function Index (FSFI, in healthy women, whose mother and father were of black race, living in municipalities from the Colombian Caribbean region, who volunteered to anonymously participate in the study, and were recruited in their communities. Higher scores correlated with better sexuality. Results: 461 women were studied; 305 (66.2% with sexual activity; 70.8% were premenopausal and 29.2%, postmenopausal. Average scores of the domains were: Sexual desire (4.1 ± 1.1, sexual arousal (4.4 ± 1.0, lubrication (4.9 ± 1.0, orgasm (4.7 ± 1.0, satisfaction (5.3 ± 1.0 and pain (4.3 ± 1.5. Average total score was 27.7 ± 4.7. Prevalence of SD was 38.4%. Smoking (OR: 3.3 [IC95%: 1.0-10.6; p = 0.041] and arterial hypertension (OR: 2.2 [IC95%:1.1-4.4; p = 0.026] increased the risk of SD, while schooling higher than ten years (OR: 0.4 [IC95%: 0.2-0.8; p = 0.003] decreased it. Prevalence of SD increased with the change in the menopausal status (p <0,001. All domains deteriorated, except pain, with the transition to the postmenopausal status (p <0.001. Conclusion: In females of African descent from the Colombian Caribbean region, one third of the premenopausal and half of the postmenopausal have SD.

  9. 针灸治疗女性更年期综合征实验研究进展%ADVANCES OF EXPERIMENTAL RESEARCH ON ACUPUNCTURE AND MOXIBUSTION FOR TREATMENT OF WOMEN'S CLIMACTERIC SYNDROME

    Institute of Scientific and Technical Information of China (English)

    陈贵珍; 许云祥

    2007-01-01

    To introduce the advances of expeyimental research on acupuncture and moxibustion for treatment of Women's Climacteric Syndrome.The recent years experimental research Iiterature of acupuncture and moxibustion for treatment of Women's Climacteric Syndrome were reviewed.The research literatures on acupuncture treatment were major,focusing on the field of acupuncture and moxibustion regulating hypothalamic-pituitary-gonad axis and nerval-endocritic-irrrnune net.Acupuncture and moxibustion could regulate the endocrine environment of menopausal women.Taking advantage of combination biomedicine with multi-sciences,to improve the acupuncture and moxibustion curative effct and probe the mechanism of menopausal pathology and acupuncture and moxibustion function to Women's Climacteric Syndrome,is the research direction afterward.%从实验研究角度对近年来针灸治疗女性更年期综合征文献报道进行综述.在各种刺激方式中.以针刺法方面的研究最多,其研究主要体现在针灸对下丘脑-垂体-性轴、神经-内分泌-免疫的影响方面.通过综述可以看到针灸对女性绝经后生殖内分泌环境有调节作用.利用生物医学与多学科交叉优势,进一步提高针灸临床疗效,力争从多层次、多指标、多学科交叉的角度,探讨更年期综合征的发病机制及针灸治疗更年期综合征的作用机制,是今后工作的重点.

  10. Hormones for therapy of climacteric afflictions

    Directory of Open Access Journals (Sweden)

    Greiner, Wolfgang

    2007-03-01

    Full Text Available Background: In Western countries hormone replacement therapy (HT is widely used in the treatment of climacteric women who are affected with hot flashes and night sweats. Besides, long-term HT was frequently used to manage the higher risks for osteoporosis and heart attack in postmenopause. Estrogens alone or combined with progestin feature most frequently in HT. Objectives: This HTA report addresses the questions on medical efficacy and cost-effectiveness of HT as a treatment of hot flashes and night sweats as well as in the primary prevention of osteoporosis and cardiovascular disease in postmenopause in general healthy women. Methods: The literature search for articles published after 1998 was conducted in March 2004 in standard medical and economic databases. The analysis included randomised controlled trials, systematic reviews, meta-analysis and economic evaluations considering relevant clinical endpoints in English or German language. The quality of the studies was assessed using checklists corresponding to the study type. Results: HT is highly effective in treating hot flashes in climacteric women. The question of economical efficiency cannot be answered due to the scarce database. As the positive effects (lower risk for fractures and endometrial cancer do not outweigh the negative effects (higher risk for breast cancer and general cardiovascular risk estrogen-progestin combination HT cannot be recommended for primary prevention of osteoporosis and cardiovascular disease in postmenopausal women. Discussion: The observation period of most of the studies regarding therapy of hot flashes and night sweats were too short to evaluate possible risks of long-term HT. The economic publications assessing HT for this indication varied vastly in terms of applied methods and were not carried out with respect to the German health care system. Conclusions: HT can be recommended in the short-term treatment of hot flashes and night sweats in climacteric

  11. [Our experience in the treatment of climacteric complaints with Livial (Organon)].

    Science.gov (United States)

    Pekhlivanov, B; Malinova, M; Milchev, N

    2001-01-01

    The authors are sharing their experience in using a new medicine Livial (Organon) for the treatment of climacteric complaints. Twenty women have been included in the study. They have received one tablet of 2.5 mg Livial daily throughout four cycles of 28 days. All women report decrease of climacteric symptoms, especially hot flushes and night sweats. Only one of them had genital bleeding while using the drug. Twenty percent of the women reported adverse effects (breast tenderness and nausea), which turned out to be transitional. Conclusions concerning the usage of Livial in the treatment of climacteric complaints have been made.

  12. O processo de viver e ser saudável das mulheres no climatério El proceso de vivir y ser saludable de las mujeres y el climaterio The living process and being healthy for women and climacteric

    Directory of Open Access Journals (Sweden)

    Maria de Fátima Mota Zampieri

    2009-06-01

    Full Text Available Este estudo teve como objetivo compreender como se dá o processo de viver de mulheres no climatério. Foi desenvolvido com base na abordagem qualitativa, utilizando multimétodos participativos, com nove mulheres do Núcleo da Terceira Idade (NETI da Universidade Federal de Santa Catarina (UFSC. Os dados foram coletados por entrevistas e reuniões de grupos e analisados por meio da análise de conteúdo. Da análise dos dados, emergiram as unidades de significado, que deram origem às seguintes categorias: afirmando-se como mulher; experienciando o climatério e o envelhecimento; interagindo no cotidiano e mantendo as singularidades; abrindo caminhos para a vivência da cidadania. Com base no resultado do estudo, o viver das mulheres no período do climatério mostrou-se como um processo complexo, dinâmico, paradoxal, em que o envelhecimento e a possibilidade de adoecer se colocam como desafios maiores e os avanços nas perspectivas pessoais, culturais e sociais, como conquistas especiais.The aim of this study was to comprehend the living process of women in the period of climacteric. It was developed based on qualitative approach, using multi-participatory methods, with nine women of the Third Age Center (NETI, of the Federal University of Santa Catarina, Brazil (UFSC. Data was collected through interviews and meetings of groups and analyzed by analysis of the content. From the data analysis, emerged the units of meaning, which led the following categories: affirming one's self as a woman; experiencing the climacteric and ageing; interacting in the day-to-day and maintaining singularities; and opening paths to the experience of citizenship. Based on the result of the study, the living of women in the climacteric period is a complex, dynamic and paradoxical process, in which the aging and the possibility of becoming ill arise as greater challenges, and advances in the personal, cultural and social perspectives as special achievements.

  13. Acupuncture for Climacteric Syndrome

    Institute of Scientific and Technical Information of China (English)

    CUI Xue-jun; HUANG Qin-feng; XIAO Yuan-chun

    2004-01-01

    共分析了50篇文章,分别采用单纯针刺法,针刺结合其他疗法,耳穴贴压疗法和其他疗法进行治疗.有39篇文章有明确的诊断标准,其中,Kupperman评分和.治疗组涉及病例总数2946例,临床疗效最高达100%,最低为58.1%.有16篇设立了对照组.15篇进行了辨证分型,共27种证型,有肝肾阴虚,脾肾阳虚,肾阳虚,肾阴虚,心肾不交和肝郁等.针灸治疗更年期综合征具有一定效果,但缺少严格的随机对照试验(RCT).%This paper reviews and analyzes 50 articles concerning the treatment of climacteric syndrome by acupuncture and moxibustion therapries. The therapies were single acupuncture, acupuncture combining other methods, auricular-plaster therapy, and some other therapies. Clear diagnostic criteria were found in 39 articles, and the most common-used criteria were Combination of TCMand Western Medicine Diagnostics and Therapeutics, Kupperman Index Scoring and Criterion of Diagnosis and Treatment Effect of TCM Diseases and Syndrome. All together 2946 cases were treated, and the therapeutic effect rates ranged from 58.1% to 100%. There were control group in 16 articles. The syndromes have been classified as 27 types in 15 articles, including type of yin-deficiency of the liver and the kidney, yang-deficiency of the spleen and the kidney, yang-deficiency of the kidney, yindeficiency of the kidney, disharmony between the heart and the kidney, and the liver stagnation, etc.Some effects have been got in treating female climacteric syndrome with acupuncture and moxibustion therapy, however, there were fewer strict randomized controlled trials (RCT).

  14. 运动疗法对防治更年期妇女骨质疏松症的临床研究%Chinical study on prevention and treatment of osteoporosis in climacteric women by sport therapy

    Institute of Scientific and Technical Information of China (English)

    陈衡; 古剑雄

    2001-01-01

    Objective To study the effect of prevention and treatment on osteoporosis in climacteric women by sport therapy. Methods 120 climacteric women were separated into rehabilitation group(n = 60)and control group(n = 60). Rehabilitation group accepted the oxygensport therapy, calcium, adjusted food. Control group was given calcium and adjusted food. The changs in densify of lumbar vertebradensify ofwere observed two yeats after treatment. Results Densify of lumbar vertebra in the rehabititation group increased( but there was no sta-tistical significance) and decreased remarkably in control group( P < 0. 05) . Densify of lumbar vertebra lumbar in rehabititation group in-creased than that of the control group( P < 0. 05) . Conclusion Exercise therapy was effective in preventing and treating osteoporosis in cli-macteric worrn.%目的探讨运动疗法对更年期妇女骨质疏松症的防治作用。方法将更年期妇女120人随机分为康复组与对照组各60人,康复组给予有氧运动、补钙、饮食调节等综合康复治疗,对照组给予补钙及饮食调节,疗程2年,观察两组治疗前后腰椎骨密度的变化。结果康复组治疗后腰椎骨密度比治疗前稍增高,但无统计学意义(P>0.05),但康复组腰椎骨密度比对照组显著增高(P<0.05)。对照组腰椎骨密度比治疗前明显降低(P<0.05)。结论运动疗法能有效地防治更年期妇女骨质疏松症。

  15. Climacteric and menopause in seven South-east Asian countries.

    Science.gov (United States)

    Boulet, M J; Oddens, B J; Lehert, P; Vemer, H M; Visser, A

    1994-10-01

    The menopause is universal, but what about the climacteric? In an attempt to answer this question, a study was conducted in seven south-east Asian countries, namely, Hong Kong, Indonesia, Korea, Malaysia, the Philippines, Singapore and Taiwan. Samples of approximately 400 women in each country were questioned about a number of climacteric complaints, incontinence and dyspareunia, consultation of a physician, menopausal status and several background characteristics. Special care was taken to overcome linguistic and cultural problems, and the data collected were kept as objective as possible. From the results obtained we were able to show that the climacteric was indeed experienced in south-east Asian countries, although in a mild form. The prevalence of hot flushes and of sweating was lower than in western countries, but was nevertheless not negligible. The percentages of women who reported the more psychological types of complaint were similar to those in western countries. The occurrence of climacteric complaints affected perceived health status. A physician was consulted for climacteric complaints by 20% of the respondents, although this was most frequently associated with the occurrence of psychological complaints and less so with that of hot flushes and sweating. The median age at menopause (51.09) appeared to be within the ranges observed in western countries. Ethnic background and age at menarche were found to have a significant influence on age at menopause. The study clearly demonstrated that climacteric complaints occur in south-east Asia. The findings suggest, however, that vasomotor-complaint-related distress might be 'translated' into psychological complaints, which are more frequently considered to warrant consulting a physician.

  16. β-受体阻滞剂干预更年期妇女心电图变化的临床价值%Clinical significance of beta-receptor blocker intervention on ECG changes in climacteric women

    Institute of Scientific and Technical Information of China (English)

    贺桦; 李针; 渠红霞; 孟凡琳; 王兵

    2015-01-01

    目的:探讨β-受体阻滞剂干预更年期妇女心电图变化的临床价值。方法选取无器质性疾病但有心电图改变的更年期妇女62例,经患者知情同意按照数字表法随机分为治疗组31例,予以β-受体阻滞剂治疗3周;另31例为对照组,不给予任何治疗。观察治疗前后2组间及治疗组心电图指标(心率、心律、ST-T)的改变。结果(1)经β-受体阻滞剂治疗3周后,2组平均心率、心律、ST-T改变(除ST上斜外)比较差异均有统计学意义(P<0.05)。(2)治疗组治疗前后比较,成对房早、ST上斜和T波倒置虽有改变,但差异无统计学意义(P>0.05);其余指标均有明显改变,差异有统计学意义(P<0.05)。结论β-受体阻滞剂应用于心电图改变的更年期妇女有一定的临床价值。%Objective To investigate the clinical significance of beta-receptor blocker intervention on ECG changes in climac-teric women.Methods Sixty-two subjects of climacteric women without organic diseases but with ECG changes were chosen and ran-domly divided into 2 groups:the control group(n=32)and the treatment group(n=30).The subjects of the control group were not giv-en any treatment, while the subjects of the treatment group were given treatment of beta-receptor blocker intervention for 3 weeks.ECG changes ( heart rate, rhythm and ST-T changes) were detected both before and after treatment, and then, comparisons were made be-tween the groups and within the groups.Results ( 1 ) After 3 weeks of beta-receptor blocker intervention, significant ECG changes could be noted in heart rate, rhythm and ST-T changes ( except ST cable) in the subjects of the treatment group, with statistical signifi-cance, when comparisons were made between the 2 groups (P0.05).There were significant changes in the remaining parameters, with statistical significance (P<0.05). Conclusion Beta-receptor blocker had its clinical

  17. 武汉市妇女绝经相关因素的调查%Survey on related factors of the climacteric syndrome among women in Wuhan city

    Institute of Scientific and Technical Information of China (English)

    卢实; 张雅君; 王声萍; 张红菱; 罗宝华; 胡引珍; 吴荣海

    2014-01-01

    Objective To investigate the epidemiologic factors associated with the menopausal symptoms among women at the age of 40 to 65 in Wuhan City.Methods From Apr.2014 to Oct , women at the age of 40 to 65 attending health examination in Wuhan City were enrolled in this study.A structured questionnaire was used to collect data of basic information, menopausal status, exercise, important physical diseases and perimenopausal symptoms.Also the menopausal symptoms were evaluated by Greene scale. The menopausal symptoms and its influencing factors were analyzed.Results The top 5 highest scores symptoms in perimenopausal women were fatigue, insomnia, dizziness or weakness, hot flashes, muscle/joint pain(P<0.01).The top highest scores syndromes in perimenopausal women were vasomotor symptoms, anxiety symptoms, somatic symptoms and depression symptoms (P<0.05).While insomnia, hot flashes, fatigue, muscle/joint pain got the highest scores symptoms in postmenopausal women (P<0.05).Vasomotor symptoms and sexual problems got the highest score syndromes in postmenopausal women ( P <0.05 ) .Somatic symptoms had a significant impact on five kinds of menopausal syndromes ( P <0.05 ) .Women at the age of 40 to 50 were more likely to have depressive symptoms than those at the age of 61 to 65 ( P <0.05 ) .Women of increasing BMI were more likely to have vasomotor symptoms( P <0.05 ) .Conclusions There were different menopausal symptoms at each stage of menopause.The main factor contributing to menopausal symptoms were somatic symptoms.%目的:评估武汉市40~65岁妇女自然绝经过程中绝经相关症状的发生及影响因素。方法选取2014年4~10月武汉市参加年度健康体检、年龄40~65岁的956名妇女为调查对象,采用问卷形式调查妇女的基本信息、月经状况、运动锻炼情况、重要躯体疾病以及围绝经期相关症状,用Greene评分法评估绝经症状,分析绝经症状的发生情况及影响因素。结果月经不

  18. The Influence of Climacteric Symptoms on Women’s Lives and Activities

    Directory of Open Access Journals (Sweden)

    Agnieszka Bień

    2015-04-01

    Full Text Available In the present study, we performed an analysis of the influence of climacteric symptoms on women’s lives and activities, i.e. their quality of life (QoL. The study was performed between October 2011 and February 2012. It included 148 women aged 44–62. The study used a diagnostic survey with questionnaires. The research instrument was the Blatt-Kupperman index. The respondents were asked to complete a questionnaire on socio-demographic data, quality of life, and the influence of climacteric symptoms on life and its various aspects. The respondents experiencing moderate or severe climacteric symptoms also had stronger feelings of failure (p = 0.005, feeling that opportunities are still available (p = 0.002, of losing their youth and beauty (p < 0.0001, compared to those who had slight or no symptoms. The intensity of climacteric symptoms significantly affects women’s lives and activities, i.e., their QoL. The reported intensity of climacteric symptoms is influenced by the respondents’ education, residence, marital status and professional activity. The more severe the climacteric symptoms, the lower the women’s quality of life, as evidenced for example by the feeling of failure and of losing one’s youth, beauty and opportunities.

  19. Autopercepción del estado de salud en climatéricas derechohabientes del Instituto Mexicano del Seguro Social Self-rated health among climacteric women affiliated to Instituto Mexicano del Seguro Social

    Directory of Open Access Journals (Sweden)

    Svetlana Vladislavovna-Doubova

    2008-10-01

    Full Text Available OBJETIVO: Evaluar la autopercepción del estado de salud positivo (APES + o negativo (APES - de mujeres climatéricas e identificar los factores relacionados con la APES-. MATERIAL Y MÉTODOS: Se analizó la información de 9 248 mujeres de 40 a 59 años. Las variables dependientes fueron la APES y las independientes las características generales, antecedentes ginecoobstétricos, enfermedades crónicas, actividad física, participación en programas de detección y educación. Se realizó un análisis descriptivo, bivariado y multivariado. RESULTADOS: Una proporción de 42% de las mujeres refirió APES+ y 58% APES-. Los factores vinculados con APES- fueron primaria completa o menos (RM=1.78; IC95% 1.62-1.95, no tener trabajo remunerado (RM=1.20; IC95% 1.09-1.33, menopausia (RM=1.22; IC95% 1.11-1.33, diabetes (RM=1.88; IC95% 1.65-2.13, hipertensión (RM=2.01; IC95% 1.82-2.22, actividad física irregular (RM=1.30; IC95% 1.12-1.50, sedentarismo (RM=1.395; IC95% 1.23-1.57, falta de integridad de detección (RM=0.82; IC95% 0.75-0.89 y de información sobre el climaterio por parte de los servicios de salud (RM=1.17; IC95% 1.07-1.28. CONCLUSIÓN: Los factores relacionados con APES- son múltiples y algunos, como la información acerca del climaterio y la actividad física, deben fortalecerse.OBJECTIVE: To evaluate self-rated health (SRH in climacteric women and to identify the factors associated with negative SRH. MATERIAL AND METHODS: Information from 9 248 women aged 40 to 59 years was analyzed. SRH was the dependent variable. Independent variables were demographic characteristics, history of reproductive and chronic diseases, physical activity, and participation in screening and health education programs. Data were analyzed using descriptive statistics, bivariate analysis, and logistic regression modeling. RESULTS: Forty-two percent of women reported positive SRH and 58% reported negative SRH. Factors associated with negative SRH were: low literacy

  20. Ensaio clínico placebo-controlado com isoflavonas da soja para sintomas depressivos em mulheres no climatério Placebo-controlled clinical trial with soy isoflavones for depressive symptoms in climacteric women

    Directory of Open Access Journals (Sweden)

    Rilva Lopes de Sousa

    2006-02-01

    Full Text Available OBJETIVOS: avaliar a eficácia do uso de isoflavonas da soja no tratamento de sintomas depressivos em mulheres com síndrome climatérica. MÉTODOS: estudo experimental placebo-controlado, randomizado e duplo-cego, com 84 pacientes climatéricas atendidas ambulatorialmente no Hospital Universitário Lauro Wanderley, em João Pessoa (PB. Na avaliação de sintomas depressivos empregou-se o Questionário de Auto-avaliação da Escala de Hamilton para Depressão (QAEH-D nas visitas pré-tratamento (VT1 e na 8ª (VT2 e na 16ª (VT3 semana pós-tratamento. O grupo experimental (GExp recebeu extrato de isoflavonas da soja, 120 mg por dia, e o controle (GCont, placebo. A comparação dos escores do QAEH-D entre os grupos em VT1, VT2 e VT3 constituiu a medida primária de eficácia (teste t, p0,05. De VT1 para VT3, evidenciou-se diferença estatisticamente significativa de 8,9% na redução dos escores entre os grupos (p=0,03. Não houve correlação da redução dos sintomas depressivos com resposta dos sintomas vasomotores (p>0,05. Houve redução das concentrações de FSH apenas no GExp (p=0,02, sem alterações do estradiol. Não ocorreram eventos adversos clinicamente relevantes. CONCLUSÕES: o efeito do extrato de isoflavonas foi superior ao do placebo, porém de pequena magnitude e apenas após 8 semanas de tratamento. Este pequeno efeito atribuído ao tratamento experimental, de boa tolerabilidade, poderá beneficiar pacientes que têm efeitos colaterais aos estrógenos ou que preferem não usar estes hormônios.PURPOSE: to evaluate the efficacy of the use of isoflavones in the treatment of depressive symptoms in climacteric women. METHODS: placebo-controlled, randomized double-blind experimental study with 84 climacteric women who were assisted at the Lauro Wanderley University Hospital Ambulatory, in João Pessoa, Paraíba, Brazil. In the evaluation of the depressive symptoms the Self-evaluation questionnare of Hamilton's rating scale for

  1. 围绝经期潮热妇女焦虑与抑郁状况的分析%Relation between Hot Flashes and Anxiety, Depression among Climacteric Women

    Institute of Scientific and Technical Information of China (English)

    张巧利; 李芬; 于英; 盛秋

    2012-01-01

    目的:探讨围绝经期前后妇女潮热与焦虑、抑郁之间的关系.方法:将符合条件的1 206名40~60岁妇女分为潮热组、无潮热组,分别完成调查问卷.问卷具体内容包括一般情况、潮热状况、焦虑自评量表(SAS)、抑郁自评量表(SDS).结果:潮热组妇女SAS和SDS的平均值高于无潮热组妇女(SAS:39.8±7.3 vs 36.0±6.1;SDS:44.1±8.3 vs 40.9±8.9,P均<0.05),潮热组轻度焦虑和抑郁的发生率明显高于无潮热组(焦虑:8.3%vs 3.4%;抑郁:23.3%vs 14.2%,P均<0.05).潮热妇女焦虑、抑郁的发生风险分别是无潮热妇女的4.1倍(95%CI,1.20~13.74)、2.4倍(95%CI,1.15~4.92).重度潮热妇女较轻度潮热妇女SAS和SDS得分均高(SAS:46.4±7.9 vs 38.8±6.6; SDS:43.9±6.9 vs 52.7±12.5,P均<0.05).潮热妇女的月经状况与SAS和SDS得分无关.结论:围绝经期潮热妇女易发生焦虑、抑郁症状,且重度潮热妇女更易发生.对妇女进行潮热治疗时,还应对妇女进行心理疏导.%Objective: To explore the relation of hot flashes, anxiety and depression among climacteric women. Methods: A total of 1 206 eligible women aged 40-60 years were divided into hot flashes group and no hot flashes group. All women were asked to finish the questionnaire. The content of questionnaire included general situation, hot flashes, anxiety (SAS) and depression (SDS) self-rating scale. Results: The mean scores of SAS and SDS in hot flashes group were higher than those in no hot flashes group (SAS: 39.8 ± 7.3 vs 36.0 ±6.1; SDS:44.1 ± 8.3 vs 40.9 ± 8.9, all P<0.05). The incidences of mild anxiety and mild depression were obviously higher than those in no hot flashes group (anxiety: 8.3% vs 3.4%; depression: 23.3% vs 14.2%; all P< 0.001). The risk of anxiety, depression among hot flashes group were 4.1-fold (OR=4.07,95%CI: 1.20-13.74) and 2.4-fold (OR=2.3S, 95%CI: 1.15-4.92) compared with no hot flashes group, respectively. The mean scores of SAS and SDS in

  2. Qualidade do sono em mulheres paulistanas no climatério Quality of sleep of climacteric women in São Paulo: some significant aspects

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    Carmen Lúcia Souza

    2005-06-01

    Full Text Available OBJETIVO: O climatério é um período de grandes transformações em que a qualidade do sono usualmente se deteriora. O objetivo foi avaliar subjetivamente a qualidade do sono em mulheres no climatério (35 a 65 anos. MÉTODOS: Um questionário contendo informações pessoais, hábitos/saúde, sexualidade e sono foi aplicado a 271 mulheres. RESULTADOS: A amostra estudada constituiu-se principalmente de mulheres casadas, ativas profissionalmente, de alta condição econômica e escolaridade, não usuárias de terapêutica hormonal da menopausa (THM, com hábito freqüente de ingerir café e com pouco consumo de álcool/tabaco. A maioria das participantes tinha hábito de jantar e de praticar atividade física. A avaliação subjetiva da qualidade do sono foi considerada ruim por 29% das mulheres da amostra. A menopausa e a autopercepção de saúde foram as únicas variáveis que exibiram relação estatisticamente significante com a qualidade do sono. Mulheres na perimenopausa (ou seja, entre 45 anos e até um ano após a menopausa e após menopausa cirúrgica declararam a pior qualidade de sono, enquanto mulheres na pré-menopausa revelaram a melhor qualidade de sono. Mulheres que se consideravam saudáveis informaram melhor qualidade de sono do que as que declararam problemas de saúde. CONCLUSÃO: A qualidade do sono piora durante o climatério e nas mulheres que se percebem doentes; ademais, há um grande desconhecimento de regras básicas de higiene do sono entre as mulheres.OBJECTIVE: To subjectively evaluate the quality of sleep in menopausal women (35 to 65 years of age METHOD: A questionnaire about personal information, habits/health, sexuality and sleep was administered to 271 women. RESULTS: The sample under study included mostly married women, professionally active with a higher education and financial status, not using menopause hormone therapy, (MHT habitual coffee drinkers and limited users of alcohol/tobacco. Most participants

  3. Female Climacteric Syndrome Treated by Ear Embedding

    Institute of Scientific and Technical Information of China (English)

    王勤

    2003-01-01

    @@ Female climacteric syndrome is a common disease occurring before and after menopause. The author has treated the disease with ear embedding therapy, and achieved satisfactory therapeutic results. The following is a report of the clinical observation.

  4. Relação cálcio/proteína da dieta de mulheres no climatério Calcium/protein relation of women on the climacteric

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    Regina das Neves Girão Montilla

    2004-01-01

    Full Text Available OBJETIVO: Avaliar a relação cálcio/proteína da dieta de mulheres no climatério. MÉTODOS: Em estudo transversal, foi avaliada a dieta de 154 mulheres entre 35 e 65 anos de idade, atendidas no Ambulatório de Saúde da Mulher Climatérica do Centro de Saúde-Escola da Faculdade de Saúde Pública da Universidade de São Paulo. Para obtenção do consumo alimentar de cálcio e de proteína, foi realizado inquérito alimentar pelo método ''recordatório de 24 horas''. A avaliação da relação cálcio/proteína foi feita segundo proposta de Massey e Heaney (1998, que é de 20/1 (mg/g. RESULTADOS: O consumo médio de cálcio foi de 624,9 mg; o de proteínas foi 86,7g e a relação cálcio/proteína foi de 7/1 (624,9mg/86,7g. CONCLUSÃO: A população estudada apresenta consumo inadequado dos nutrientes cálcio e proteína, podendo resultar em sérios riscos à saúde.OBJECTIVE: To evaluate the calcium/protein relation of the diet of climacteric women. METHODS: In a transversal study the diet was evaluated of 154 women 35-65 years old and matriculated in the Health Clinic of the Climateric Woman of Health Center of Public Health College of the São Paulo University. The food intake of calcium and protein was food investigated by ''24 hours recall'' method. The evaluation of calcium/protein relation was made according to Massey and Heaney (1998, that is 20/1 (mg/g. RESULTS: The mean of intake of calcium was 624.9 mg; the mean of intake of protein was 86.7 g and the calcium/protein relation was 7/1 (624.9 mg/86.7 g. CONCLUSION: The studied population presents inadequated consumation of the calcium and protein nutrients. It could result in serious risk for health.

  5. Identification of Differentially Expressed Genes During Ethylene Climacteric of Melon Fruit by Suppression Subtractive Hybridization

    Institute of Scientific and Technical Information of China (English)

    GAO Feng; NIU Yi-ding; HAO Jin-feng; BADE Rengui; ZHANG Li-quan; HASI Agula

    2013-01-01

    Melon (Cucumis melo L.) is an important horticultural crop worldwide. Ethylene regulates the ripening process and affects the ripening rate. To screen genes that are differentially expressed at the burst of ethylene climacteric in melon fruit, we performed suppression subtractive hybridization (SSH) to generate forward and reverse libraries, for which we sequenced 439 and 445 clones, respectively. Our BLAST analysis showed that the genes from the 2 libraries were involved in metabolism, signal transduction, cell structure, transcription, translation, and defense. Six genes were analyzed by qRT-PCR during the differential developmental stage of melon fruit. Our results provide new insight into the understanding of climacteric ripening of melon fruit.

  6. Sintomas climatéricos e estado nutricional de mulheres na pós-menopausa usuárias e não usuárias de terapia hormonal Climacteric symptoms and nutritional status of women in post-menopause users and non-users of hormone therapy

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    Angela Andréia França Gravena

    2013-04-01

    Full Text Available OBJETIVO: Analisar os sintomas climatéricos e estado nutricional em mulheres na pós-menopausa, usuárias e não usuárias de terapia hormonal (TH. MÉTODOS: Estudo analítico, exploratório, tipo inquérito populacional domiciliar, realizado na área urbana do município de Maringá, Paraná, incluindo 456 mulheres com idade entre 45 e 69 anos, no período pós-menopausa. A coleta teve como base de referência os setores censitários urbanizados (368 do município, de acordo com o Censo Demográfico Brasileiro. Foi utilizada amostra aleatória simples proporcional às mulheres residentes em cada setor censitário e, por meio de visita domiciliar, aplicou-se um questionário e verificaram-se as medidas antropométricas e pressão arterial. Para avaliação dos sintomas climatéricos, foi utilizado o Índice Menopausal de Blatt e Kupperman. A variável desfecho foi o uso de TH. RESULTADOS: A média de idade foi de 58,7 anos. O excesso de peso esteve presente em 72,6% das mulheres e a obesidade abdominal em 81,4% delas. Sintomas climatéricos de intensidade leve foram evidenciados em 69,5% das mulheres. Apenas 18,4% das mulheres faziam uso de TH e eram, na sua maioria, brancas, não fumantes, sem comorbidades e sem companheiro. Usuárias de TH apresentaram menor frequência de excesso de peso e obesidade abdominal e tiveram menor prevalência de sintomas climatéricos de intensidade severa. CONCLUSÃO: O excesso de peso e a obesidade abdominal foram prevalentes na amostra estudada. Embora em menor número, as usuárias de TH apresentaram uma frequência menor de excesso de peso e sintomas climatéricos leves e intensos na pós-menopausa.PURPOSE: To analyze the climacteric symptoms, nutritional status and distribution of abdominal fat in postmenopausal women using or not hormone therapy. METHODS: exploratory analytical study of the population survey type in the urban area of Maringa, Parana, conducted on 456 postmenopausal women aged 45 to 69

  7. Influence of health education and psychological nursing intervention on symptoms and sleep for climacteric syndrome women%健康教育与心理护理对女性更年期综合征患者症状及睡眠状况的影响

    Institute of Scientific and Technical Information of China (English)

    沈斌; 王立新

    2014-01-01

    目的:观察健康教育和心理护理干预对伴更年期综合征女性患者的临床影响,探讨改善伴有更年期综合征临床表现的护理措施。方法选择更年期综合征女性患者96例,随机均分为对照组和干预组,对照组给予药物治疗,干预组在药物治疗基础上定期进行健康教育和心理护理干预,治疗两个月后比较两组患者汉密尔顿抑郁量表( HAMD)和焦虑量表( HAMA)、匹茨堡睡眠质量指数( PSQI)及更年期症状改善情况。结果治疗两个月后干预组的HAMD和HAMA评分均低于对照组,差异有统计学意义(t值分别为1.833,1.792;P<0.05)。治疗后干预组睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍情况均有好转,差异有统计学意义(t 值分别为5.236,1.914,1.721,1.703,1.715;P<0.05)。结论女性更年期综合征患者的常规治疗过程中应积极进行健康教育和心理护理干预。%Objective To observe the clinical influence of health education and psychological nursing intervention on the climacteric syndrome and discuss the methods to improve clinical syndromes . Methods Totals of 96 women with climacteric syndrome were enrolled .Totals of 48 patients were distributed to the conventional group treated by drugs , and 48 patients were distributed to the intervention group treated by drugs and health education and psychological nursing intervention .Then, the Hamilton Depression Scale ( HAMD) score, Hamilton Anxiety Scale ( HAMA ) score, Pittsburgh Sleep Quality Index ( PSQI ) and climacteric syndrome’s improvement conditions were compared between groups after two months ’ treatment. Results The HAMD score and HAMA score of the intervention group were lower than those of the conventional group.The differences were statistically significant ( t=1.833, 1.792, respectively; P<0.05).The sleep quality, the time to fall asleep, time of sleep

  8. Avaliação da sintomatologia depressiva de mulheres no climatério com a escala de rastreamento populacional para depressão CES-D Depressive symptoms in climacteric women evaluated by the Center for Epidemiological Studies Depression Scale

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    Rita de Cássia Leite Fernandes

    2008-12-01

    climacteric women using the Center for Epidemiological Studies Depression Scale (CES-D from the National Institute of Mental Health (USA. METHOD: This is a cross-sectional study carried out in a gynecological outpatient unit in Rio de Janeiro, Brazil, including 151 climacteric women between 40 and 65 years of age. The CES-D was used to assess depressive symptoms and a structured interview obtained sociodemographic, clinical and gynecological data. A score above 15 points on the CES-D was considered as a cut-point for depressive state. RESULTS: Mean CES-D score was 9.2 points (standard deviation = 9.0. Insomnia, sadness and despondency had the highest scores. There was no significant association between CES-D scores and the climacteric period, sociodemographic, clinical or gynecological characteristics, except for women with psychiatric symptoms, history of depression or on antidepressants (p = 0.000. In 32 women (21% who scored > 15 on the CES-D, 72% had already suffered from a depressive state. Women with no history of depressive disorder scored more frequently above 15 when they were perimenopausal. CONCLUSION: This sample of climacteric women, from a non-specialized mental or menopausal health service, had low mean scores on the CES-D, with the item insomnia being the most highly scored. History of a previous depressive episode, but not the woman's climacteric period, was a risk factor for higher scores on the CES-D. In the group of women with no history of depression, the perimenopausal women had more scores above the cut-point. This fact may suggest that the perimenopause is a period of higher susceptibility to new onset of depressive episodes.

  9. Fatores indicadores da sintomatologia climatérica Predicting factors of climacteric symptoms

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    Dino Roberto Soares De Lorenzi

    2005-01-01

    women aged between 45 and 60 years was carried out at the Climacterium Outpatient Clinic of Caxias do Sul University, RS, from June to October 2002. Women with previous hysterectomy or under hormonal therapy were excluded. The climacteric symptoms were evaluated by means of the Kuppermann index and the attitudes toward menopause by a specific questionnaire. Data were analyzed by Student's t test, analysis of variance (ANOVA and multiple linear regression analysis. RESULTS: twenty eight percent of the women reported mild climacteric symtoms, whereas 42.3% reported moderate symptoms and 30.7%, intense symptoms. The most prevalent symptoms were: irritability (87.1%, arthralgias/myalgias (77.5% and melancholy (73.2%, while the most severe were hot flushes in 60.2% of the women, irritability and insomnia. Attitudes toward menopause, skin color and physical activity were predictors of climacteric symptoms. Positive attitudes toward menopause (p=0.01, white color (p=0.02 and the habit of practicing physical activity (0.04 were associated with less intense climacteric symptoms. Negative attitudes toward menopause were associated with worse climacteric symptoms (p<0.01. CONCLUSIONS: in the current study, the climacteric symptoms were influenced by psychosocial factors and physical activity, as well as by climacteric hypoestrogenism.

  10. Treatment results in women with clinical stage I and pathologic stage II endometrial carcinoma.

    Science.gov (United States)

    Jobsen, J J; Schutter, E M; Meerwaldt, J H; Van Der Palen, J; Van Der Sijde, R; Ten Cate, L N

    2001-01-01

    The aim of this study is to report survival and results of therapy and possible prognostic factors in women with pathologic stage II endometrial carcinoma. Forty-two patients with pathologic stage II endometrial carcinoma were treated at the department of Radiation Oncology of the Medisch Spectrum Twente between 1987 and 1998. All patients received external radiotherapy following standard surgical procedures and no adjuvant systemic therapy was given. From the 42 patients 21 had a pathologic stage IIA and 21 stage IIB. The median follow-up was 62 months. The overall recurrence rate was 21.5% (9/42). Seven patients had distant metastasis, of which three also had locoregional recurrence, vaginal vault and/or pelvic. The presence of myometrial invasion (> (1/2)) and/or lymph-angioinvasion showed a significant relation with distant metastasis (P = 0.017). Stage IIB showed more recurrences, 33% (7/21). There was a significant different 5-year disease specific survival for stage IIA and IIB, respectively, 95% and 74% (P = 0.0311). Patients with a differentiation grade 3 and stage IIB showed a significantly poorer (P = 0.003) 5-year survival of 48.6% (P = 0.003). Results obtained in the present series of patients are in accordance with the literature. The present treatment policy seems justified, except for patients with pathologic stage IIB and grade 3, in which a more aggressive treatment should be considered.

  11. A comparative study of Klimakt-Heel® and Femolene Ultra in the management of typical climacteric symptoms

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    Marilena Deroukakis

    2009-04-01

    Full Text Available The climacteric is described as the physiological cessation of menses due to a decrease in ovarian function. Typically, women between the ages of 44 and 57 years old are symptomatically affected by it. During this stage of life, a woman may experience what is referred to as ‘typical climacteric symptoms’ of varying intensity, including vasomotor reactions, increased perspiration, sleeping problems, mood changes, headaches, joint pains and urogenital problems.

    The aim of this study was to determine the effectiveness of Femolene Ultra (phytotherapeutic preparation and Klimakt-Heel® (homeopathic preparation in the treatment of typical climacteric symptoms.

    Thirty female volunteers between the ages of 44 and 57 years suffering from climacteric symptoms were recruited and asked to complete the Patient Profile and Case History Form and to sign a Patient Information and Consent Form. These participants were randomly placed in two groups of fifteen. One group received Femolene Ultra and the other received Klimakt-Heel® for a period of 12 weeks. The trial was blinded as neither the researcher nor the participant was aware of which treatment was being administered. Blood samples were taken to ascertain the 17ß oestradiol levels before and after the 12-week period. The Kupperman Menopause Index (KMI was used as a self-report measure and completed at four-weekly intervals. For statistical purposes, the Wilcoxon Signed Rank Test, from the class of non-parametric distribution-free tests, was used.

    Both products served to decrease the typical climacteric symptoms significantly within the 12-week period. Femolene Ultra decreased the average Kupperman Menopause Index (KMI score by 63% (26.2 to 16.4 and Klimakt-Heel® decreased the average score by 54% (28.4 to 15.28, although more participants in the Klimakt-Heel® group experienced amelioration of climacteric symptoms. The results are not conclusive, but they do provide an interesting base

  12. 黄可佳教授治疗更年期综合征经验%Professor HUANG Ke-jia′s Summary on Treatment of Climacteric Syndrome

    Institute of Scientific and Technical Information of China (English)

    刘楠楠

    2011-01-01

    更年期综合征是妇科最常见的疾病之一,随着现代社会经济文化的飞速发展,处于更年期阶段的女性,在快节奏的生活,繁重的体力、脑力劳动等压力下,机体内分泌系统的变化愈加明显,导致出现一系列更年期症状带给人们大的压力,尤其是处于更年期的女性所要面临的一个重大问题.中医理论认为,更年期综合征以肾虚为本,又常见肝、脾、心等功能的失调,表现为月经紊乱、烘热汗出、头晕乏力、失眠健忘、烦躁易怒等一系列症候.对于更年期阶段的女性所出现的上述症状,导师黄可佳教授依据多年临床经验,审因施治,形成独到的治疗方法,取得了较好的临床疗效.%The climacteric syndrome is one of the most common diseases in gynecology department, with the rapid development of modem social, economic and cultural, women in menopause stage, in the fast-paced life, under the pressure of heavy physical, mental and others, obvious changes of the body's endocrine system, leading to a range of symptoms of menopause brought people pressure, especially in menopausal women who have to face a major problem. In the Chinese medicine theory, The climacteric syndrome take the kidney deficiency as the essence, and some common features such as liver, spleen, heart disorders at the same time, expressing menstrual disorders, baking hot forgetful sweating, dizziness, fatigue, insomnia, irritability and irritable and a series of syndromes. Above symptom which appears regarding the climacteric stage's female, Professor HUANG Ke-jia rests on many years clinical experience, treats the sickness according to cause of disease, forms the original method of treatment, and has obtained the good clinical curative effect.

  13. Traditional Chinese medicine valuably augments therapeutic options in the treatment of climacteric syndrome.

    Science.gov (United States)

    Eisenhardt, Sarah; Fleckenstein, Johannes

    2016-07-01

    Climacteric syndrome refers to recurring symptoms such as hot flashes, chills, headache, irritability and depression. This is usually experienced by menopausal women and can be related to a hormonal reorganization in the hypothalamic-pituitary-gonadal axis. In Traditional Chinese Medicine, originating 1000s of years ago, above-mentioned symptoms can be interpreted on the basis of the philosophic diagnostic concepts, such as the imbalance of Yin and Yang, the Zang-Fu and Basic substances (e.g. Qi, Blood and Essence). These concepts postulate balance and harmonization as the principle aim of a treatment. In this context, it is not astounding that one of the most prominent ancient textbooks dating back to 500-200 BC, Huang di Neijing: The Yellow Emperor's Classic of Internal Medicine gives already first instructions for diagnosis and therapy of climacteric symptoms. For therapy, traditional Chinese medicine comprises five treatment principles: Chinese herbal medicine, TuiNa (a Chinese form of manual therapy), nutrition, activity (e.g. QiGong) and acupuncture (being the most widespread form of treatment used in Europe). This review provides an easy access to the concepts of traditional Chinese medicine particularly regarding to climacteric syndrome and also focuses on current scientific evidence.

  14. Depressão em mulheres climatéricas: análise de mulheres atendidas ambulatorialmente em um hospital universitário no Maranhão Depression in climacteric women: analysis of a sample receiving care at a university hospital in Maranhão, Brazil

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    Mari-Nilva Maia da Silva

    2008-08-01

    Full Text Available Introdução: O climatério, período de transição entre a fase reprodutiva e não-reprodutiva, ocasiona mudanças biopsicossociais nas mulheres que o vivenciam. A associação entre a maior prevalência de depressão nesse período é, no entanto, ainda controversa. O objetivo deste estudo foi avaliar a prevalência de depressão em mulheres climatéricas atendidas em um hospital universitário numa cidade da Região Nordeste do Brasil e identificar fatores associados. Método: Foi realizado um estudo prospectivo e analítico de 70 mulheres climatéricas. O diagnóstico de depressão foi dado segundo critérios diagnósticos da Classificação Internacional de Doenças em um período de seguimento mínimo de 3 meses. Foram investigadas as seguintes variáveis: escolaridade, situação conjugal, renda pessoal, gravidade da depressão segundo escala de Hamilton, presença e intensidade de sintomas climatéricos, menopausa (natural ou cirúrgica, dependência econômica do parceiro, antecedentes familiares de depressão, história prévia de depressão pós-parto, episódios depressivos e transtorno disfórico pré-menstrual, alterações da função sexual e visão positiva ou negativa da menopausa. Resultados: Um percentual de 34,3% das pacientes apresentou depressão, sendo 70,8% destas na categoria leve da escala de Hamilton. Não houve associação estatisticamente significante entre variáveis socioeconômicas, diminuição da libido e antecedentes familiares de depressão com a presença de depressão. Houve associação entre a presença de depressão e pacientes com sintomas vasomotores (p = 0,03, insônia (p Introduction: The climacteric is a transition period between reproductive and non-reproductive ages that leads to biopsychossocial changes in women who experience it. However, association between a larger prevalence of depression in this period is still controversial. The objective of this study was to assess the prevalence of

  15. Prevalence and factors associated with urinary incontinence in climacteric

    Directory of Open Access Journals (Sweden)

    Máyra Cecilia Dellú

    Full Text Available SUMMARY Objective: To estimate the prevalence and identify associated factors to urinary incontinence (UI in climacteric women. Method: In a cross-sectional study with a stratified random sample, 1,200 women aged between 35 and 72 years were studied, enrolled in the Family Health Strategy in the city of Pindamonhangaba, São Paulo. Urinary incontinence was investigated using the International Consultation of Incontinence Questionnaire - Short Form, while associated factors were assessed based on a self-reported questionnaire with socio-demographic, obstetric and gynecological history, morbidities and drug use. The prevalence of urinary incontinence was estimated with a 95% confidence interval (95CI and the associated factors were identified through multiple logistic regression model performed using Stata software, version 11.0. Results: Women had a mean age of 51.9 years, most were in menopause (59.4%, married (87.5%, Catholic (48.9%, and declared themselves black or brown (47.2%. The mean age of menopause of women with UI was 47.3 years. The prevalence of UI was 20.4% (95CI: 17.8-23.1%. The factors associated with UI were urinary loss during pregnancy (p=0.000 and after delivery (p=0.000, genital prolapse (p=0.000, stress (p=0.001, depression (p=0.002, and obesity (p=0.006. Conclusion: The prevalence of UI was lower but similar to that found in most similar studies. Factors associated with the genesis of UI were urinary loss during pregnancy and after delivery, genital prolapse and obesity.

  16. [Assistance to the climacteric woman: new paradigms].

    Science.gov (United States)

    Lorenzi, Dino Roberto Soares De; Catan, Lenita Binelli; Moreira, Karen; Artico, Graziela Rech

    2009-01-01

    Population aging is a demographic reality for Brazil. Consequently, in the next years it is expected a progressive increase in seeking health care services in the country by women with complaints related to climacterium. Parallel to it, assistance at this part of woman's life has been going through a paradigm shift which has imposed to health professionals a change of attitude in relation to this stage of woman's life. Today it is acknowledged that the climacterium is influenced by biological, psychosocial and cultural factors, whose knowledge is fundamental for planning a more qualified and humanized care. This article proposes a reflection on the paradigm shifts in assistance at climacterium, highlighting important aspects as multidisciplinarity and interdisciplinarity, so as to serve better this portion of population, and provide it with more integrated and individualized care, bringing together knowledge and sensitivity, and always aiming at a better quality of life.

  17. 'Movers and shakers' in the regulation of fruit ripening: a cross-dissection of climacteric versus non-climacteric fruit.

    Science.gov (United States)

    Cherian, Sam; Figueroa, Carlos R; Nair, Helen

    2014-09-01

    Fruit ripening is a complex and highly coordinated developmental process involving the expression of many ripening-related genes under the control of a network of signalling pathways. The hormonal control of climacteric fruit ripening, especially ethylene perception and signalling transduction in tomato has been well characterized. Additionally, great strides have been made in understanding some of the major regulatory switches (transcription factors such as RIPENING-INHIBITOR and other transcriptional regulators such as COLOURLESS NON-RIPENING, TOMATO AGAMOUS-LIKE1 and ETHYLENE RESPONSE FACTORs), that are involved in tomato fruit ripening. In contrast, the regulatory network related to non-climacteric fruit ripening remains poorly understood. However, some of the most recent breakthrough research data have provided several lines of evidences for abscisic acid- and sucrose-mediated ripening of strawberry, a non-climacteric fruit model. In this review, we discuss the most recent research findings concerning the hormonal regulation of fleshy fruit ripening and their cross-talk and the future challenges taking tomato as a climacteric fruit model and strawberry as a non-climacteric fruit model. We also highlight the possible contribution of epigenetic changes including the role of plant microRNAs, which is opening new avenues and great possibilities in the fields of fruit-ripening research and postharvest biology.

  18. The non-estrogenic alternative for the treatment of climacteric complaints: Black cohosh (Cimicifuga or Actaea racemosa).

    Science.gov (United States)

    Wuttke, Wolfgang; Jarry, Hubertus; Haunschild, Jutta; Stecher, Guenter; Schuh, Markus; Seidlova-Wuttke, Dana

    2014-01-01

    In postmenopausal women estrogens in combination with progestins have beneficial effects on climacteric complaints and on osteoporosis but this hormone replacement therapy (HRT) bears the risk of increased mammary carcinomas and cardiovascular diseases. Phytoestrogens at low doses have little or no effects on climacteric complaints, at high doses they mimic the effects of estrogens. Therefore other plant derived substances are currently intensively investigated. Extracts of the rhizome of black cohosh (Cimicifuga racemosa=CR) did not bind to estrogen receptors and were shown to be devoid of estrogenic effects on mammary cancer cells in vitro and on mammary gland and uterine histology in ovariectomized rats. In addition in this rat model the special extract CR BNO 1055 inhibited the occurrence of hot flushes and development of osteoporosis. In postmenopausal women CR BNO 1055 reduced major climacteric complaints as effectively as conjugated estrogens and significantly more than placebo. Similar data were published for other European CR preparations whereas 2 US American preparations were ineffective. This was most likely due to the too high doses or due to the adulteration with Asian Cimicifuga preparations. In all European studies neither effects in the uterus nor in mammary glands were observed. The effective compounds in CR are most likely neurotransmitter-mimetic in nature: dopaminergic, noradrenergic, serotoninergic and GABAergic effects were demonstrated and some have been structurally identified. We conclude that CR extracts at low doses are effective to ameliorate climacteric complaints but are devoid of adverse estrogenic effects. These finding strengthens the role of CR extracts as substitutes for HRT. This article is part of a special issue entitled: Special Issue on Phytoestrogens.

  19. The battle for centre stage: Women's football in South Africa

    DEFF Research Database (Denmark)

    Engh, Mari Haugaa

    2010-01-01

    From when the first official South African Women's National Football team was established in 1993, Banyana Banyana have been 'making it happen' for women's football in South Africa. National team players have become inspirational icons and role models for thousands of South African women and girls....... This Focus draws on academic research, media reports and interviews with national team players to highlight the struggles and victories of South African women footballers over the last 40 years. Despite numerous challenges and setbacks, womenB football has experienced immense growth over the past 15 years....... Highlighting examples of battles for power and leadership, homophobic attitudes and attempts to feminise the bodies of women footballers, this Focus illustrates the hard fought victories and disappointing losses in the history of South African women's football....

  20. Involvement of wound and climacteric ethylene in ripening avocado discs.

    Science.gov (United States)

    Starrett, D A; Laties, G G

    1991-10-01

    Avocado (Persea americana Mill. cv Hass) discs (3 mm thick) ripened in approximately 72 hours when maintained in a flow of moist air and resembled ripe fruit in texture and taste. Ethylene evolution by discs of early and midseason fruit was characterized by two distinct components, viz. wound ethylene, peaking at approximately 18 hours, and climacteric ethylene, rising to a peak at approximately 72 hours. A commensurate respiratory stimulation accompanied each ethylene peak. Aminoethoxyvinyl glycine (AVG) given consecutively, at once and at 24 hours following disc preparation, prevented wound and climacteric respiration peaks, virtually all ethylene production, and ripening. When AVG was administered for the first 24 hours only, respiratory stimulation and softening (ripening) were retarded by at least a day. When AVG was added solely after the first 24 hours, ripening proceeded as in untreated discs, although climacteric ethylene and respiration were diminished. Propylene given together with AVG led to ripening under all circumstances. 2,5-Norbornadiene given continuously stimulated wound ethylene production, and it inhibited climacteric ethylene evolution, the augmentation of ethylene-forming enzyme activity normally associated with climacteric ethylene, and ripening. 2,5-Norbornadiene given at 24 hours fully inhibited ripening. When intact fruit were pulsed with ethylene for 24 hours before discs were prepared therefrom, the respiration rate, ethylene-forming enzyme activity buildup, and rate of ethylene production were all subsequently enhanced. The evidence suggests that ethylene is involved in all phases of disc ripening. In this view, wound ethylene in discs accelerates events that normally take place over an extended period throughout the lag phase in intact fruit, and climacteric ethylene serves the same ripening function in discs and intact fruit alike.

  1. Factors influencing the fulfillment of women's preferences for birthing positions during second stage of labor.

    Science.gov (United States)

    Nieuwenhuijze, Marianne; de Jonge, Ank; Korstjens, Irene; Lagro-Jansse, Toine

    2012-03-01

    Having choices and being involved in decision making contributes to women's positive childbirth experiences. During a physiological birth, women's preferences can play a leading role in the choice of birthing positions. In this study, we explored women's preferences with regard to birthing positions during second stage of labor, with a special focus on women who preferred positions other than common supine positions. A questionnaire survey was conducted among women in 54 Dutch midwifery practices. Of the 1154 women in the study, 58.9% preferred supine positions, 19.6% preferred other positions (e.g. sitting or standing), and 21.5% had no distinct preference. Women who preferred supine positions gave birth in these positions more often than women with preferences for other positions. Among the women having a preference for other positions, the actual fulfillment of their preference was related to longer duration of second stage of labor, higher levels of education, the strength of the preference, and giving birth at home. These results demonstrate differences in women's use of preferred positions during childbirth. Midwives can contribute to women-centered care by proactively exploring women's preferences for birthing positions throughout pregnancy and birth, supporting women in developing well-informed choices and facilitating these choices where possible.

  2. Stage at diagnosis and mortality in women with pregnancy-associated breast cancer (PABC).

    Science.gov (United States)

    Johansson, Anna L V; Andersson, Therese M-L; Hsieh, Chung-Cheng; Jirström, Karin; Dickman, Paul; Cnattingius, Sven; Lambe, Mats

    2013-05-01

    Converging evidence indicates that women with pregnancy-associated breast cancer (PABC) have increased mortality compared to women with breast cancer not diagnosed near pregnancy (non-PABC). Our aim was to investigate if the stage distribution differs between PABC and non-PABC and if stage at diagnosis can explain the poorer prognosis observed among women with PABC. We identified 3,282 breast cancers in women aged 15-44 years at diagnosis for whom staging data (tumor size, nodal involvement, metastasis) were available in the Swedish Cancer Register between 2002 and 2009. Information on reproductive history and vital status was obtained from the Multi-Generation Register and the Cause of Death Register. PABC was defined as breast cancers diagnosed during pregnancy and up to 2 years after delivery (n = 317). Non-PABC was defined as cases diagnosed before pregnancy or more than 2 years postpartum. Stage distributions were compared between PABC and non-PABC, and mortality rates were modeled using Cox regression. Compared to women with non-PABC, the mortality was almost 50 % higher in women with PABC [unadjusted hazard ratio (HR) 1.47 (95 % CI 1.04-2.08)], a difference which was reduced after adjustment for age and calendar year of diagnosis [HR 1.27 (95 % CI 0.88-1.83)]. Although advanced stage of breast cancer at diagnosis was more common among PABC than among non-PABC, further adjustment for stage only slightly reduced the HR [1.22 (95 % CI 0.84-1.78)]. The difference in mortality between PABC and non-PABC was more pronounced among women above 35 years and among women with PABC diagnosed within 1 year postpartum. Age, rather than stage at diagnosis, appears to act as the principal driver of the increased mortality observed in women with PABC. However, these findings do not preclude an untoward influence on mortality by pregnancy-associated factors affecting tumor aggressiveness and progression.

  3. Successful pregnancy outcome among women with end-stage renal disease requiring haemodialysis.

    Science.gov (United States)

    Arora, Nalini; Mahajan, Kirti; Jana, Narayan; Maiti, Tapan Kumar; Mandal, Debasmita; Pandey, Rajendra

    2009-04-01

    Pregnancy is rare in women with end-stage renal disease, and perinatal outcome remains suboptimal because of prematurity and foetal growth restriction. Successful obstetrical outcome in two women presented with chronic renal failure requiring serial haemodialysis and multiple blood transfusions during pregnancy is reported. Both women had vaginal delivery of low birth weight neonates--2100 g and 1540 g at 33 and 37 weeks' gestations respectively. With specialised neonatal care, both neonates survived, and the mothers were counselled for renal replacement therapy.

  4. Women's positions during the second stage of labour: Views of primary care midwives

    NARCIS (Netherlands)

    Jonge, A. de; Teunissen, T.A.M.; Diem, M.T. van; Scheepers, P.L.H.; Lagro-Janssen, A.L.M.

    2008-01-01

    Aim. This paper is a report of a study to explore the views of midwives on women's positions during the second stage of labour. Background. Many authors recommend encouraging women to use positions that are most comfortable to them. Others advocate encouragement of non-supine positions, because offe

  5. Women's positions during the second stage of labour : views of primary care midwives

    NARCIS (Netherlands)

    Teunissen, Doreth A. M.; van Diem, Mariet Th.; Scheepers, Peer L. H.; Lagro-Janssen, Antoine L. M.

    2008-01-01

    Aim. This paper is a report of a study to explore the views of midwives on women's positions during the second stage of labour. Background. Many authors recommend encouraging women to use positions that are most comfortable to them. Others advocate encouragement of non-supine positions, because offe

  6. Women's positions during the second stage of labour: Views of primary care midwives

    NARCIS (Netherlands)

    Jonge, A. de; Teunissen, T.A.M.; Diem, M.T. van; Scheepers, P.L.H.; Lagro-Janssen, A.L.M.

    2008-01-01

    AIM: This paper is a report of a study to explore the views of midwives on women's positions during the second stage of labour. BACKGROUND: Many authors recommend encouraging women to use positions that are most comfortable to them. Others advocate encouragement of non-supine positions, because offe

  7. Fatores Associados à Obesidade e ao Padrão Andróide de Distribuição da Gordura Corporal em Mulheres Climatéricas Factors Related to Obesity and Android Pattern of Body Fat Distribution in Climacteric Women

    Directory of Open Access Journals (Sweden)

    Diana Beatriz Filip Raskin

    2000-08-01

    Full Text Available Objetivos: descrever as características de um grupo de mulheres climatéricas, conhecer a freqüência e os fatores associados à obesidade e ao padrão andróide de distribuição da gordura corporal. Métodos: estudo observacional com 518 pacientes com idade entre 45 e 65 anos em um ambulatório de climatério. Foram considerados a idade, cor, status menopausal, tempo de menopausa, atividade física, tabagismo, dieta, etilismo, antecedentes pessoais e familiares de hipertensão, diabetes, doença cardiovascular, dislipidemia e obesidade. O índice de massa corpórea e a relação das medidas cintura/quadril foram variáveis dependentes. Na análise estatística utilizaram-se os testes de Wilcoxon, c² de Pearson, com nível de significância de 5%, e análise múltipla por regressão logística. Resultados: mais de dois terços das participantes eram não-obesas com perfil andróide e menopausadas. Aproximadamente um quarto tinha atividade física adequada, era tabagista, metade referiu dieta inadequada e um quinto era etilista. Pacientes com perfil andróide apresentaram média etária maior que mulheres com padrão ginecóide. Antecedentes pessoais de obesidade, hipertensão, diabetes e história familiar de diabetes relacionaram-se com obesidade e padrão andróide. O status pós-menopausa associou-se significativamente ao perfil andróide. Conclusões: a maioria das mulheres foram não-obesas com perfil andróide, brancas, pós-menopáusicas, sedentárias, não-tabagistas nem etilistas. Os principais fatores associados à obesidade e padrão andróide foram os antecedentes pessoais de obesidade, hipertensão arterial, diabetes, história familiar de diabetes e, particularmente, o status pós-menopausa com o perfil andróide.Purpose: to describe sociodemographic characteristics of a group of climacteric women in order to discover the frequency and the variables associated with obesity and android profile of body fat distribution. Methods

  8. Musculoskeletal pain and the reproductive life stage in women: is there a relationship?

    Science.gov (United States)

    Frange, C; Hirotsu, C; Hachul, H; Pires, J S; Bittencourt, L; Tufik, S; Andersen, M L

    2016-06-01

    Objectives To investigate the association between reproductive life stage, pain perception and musculoskeletal pain complaint in a representative sample of women from São Paulo, Brazil. Methods A population-based survey was carried out with 574 women who were classified as being in the premenopausal or postmenopausal stage. They answered questions about pain perception and musculoskeletal pain. Follicle stimulating hormone was collected to confirm menopausal condition along with clinical evaluation. Results In the whole sample, we found a prevalence of 56% for pain perception and 20.2% for complaints of musculoskeletal pain. Regarding the topography of musculoskeletal pain, the distributions were similar among the premenopausal and postmenopausal groups. No significant association was found between reproductive life stage and pain perception, as 58.1% of the premenopausal group and 52.0% of the postmenopausal group reported pain. Similarly, there was no significant association between menopausal stage and musculoskeletal pain, as 19.5% and 21.6% of the premenopausal and postmenopausal women, respectively, complained of musculoskeletal pain. There was no significant association of postmenopausal stage (early or late) with pain perception or musculoskeletal pain. The use of analgesics was significantly higher in postmenopausal compared to premenopausal women (p musculoskeletal pain nor pain perception were associated with the reproductive life stage, showing that both parameters was independent from the menopausal status in the studied women.

  9. A non-climacteric fruit gene CaMADS-RIN regulates fruit ripening and ethylene biosynthesis in climacteric fruit.

    Directory of Open Access Journals (Sweden)

    Tingting Dong

    Full Text Available MADS-box genes have been reported to play a major role in the molecular circuit of developmental regulation. Especially, SEPALLATA (SEP group genes play a central role in the developmental regulation of ripening in both climacteric and non-climacteric fruits. However, the mechanisms underlying the regulation of SEP genes to non-climacteric fruits ripening are still unclear. Here a SEP gene of pepper, CaMADS-RIN, has been cloned and exhibited elevated expression at the onset of ripening of pepper. To further explore the function of CaMADS-RIN, an overexpressed construct was created and transformed into ripening inhibitor (rin mutant tomato plants. Broad ripening phenotypes were observed in CaMADS-RIN overexpressed rin fruits. The accumulation of carotenoid and expression of PDS and ZDS were enhanced in overexpressed fruits compared with rin mutant. The transcripts of cell wall metabolism genes (PG, EXP1 and TBG4 and lipoxygenase genes (TomloxB and TomloxC accumulated more abundant compared to rin mutant. Besides, both ethylene-dependent genes including ACS2, ACO1, E4 and E8 and ethylene-independent genes such as HDC and Nor were also up-regulated in transgenic fruits at different levels. Moreover, transgenic fruits showed approximately 1-3 times increase in ethylene production compared with rin mutant fruits. Yeast two-hybrid screen results indicated that CaMADS-RIN could interact with TAGL1, FUL1 and itself respectively as SlMADS-RIN did in vitro. These results suggest that CaMADS-RIN affects fruit ripening of tomato both in ethylene-dependent and ethylene-independent aspects, which will provide a set of significant data to explore the role of SEP genes in ripening of non-climacteric fruits.

  10. Comparison of the effect of Foeniculum vulgare and St John’s wort (Hypericum perforatum on the climacteric symptoms and sexual activity in menopausal woman

    Directory of Open Access Journals (Sweden)

    Khadijeh Abdali

    2016-01-01

    Full Text Available Background and objective: Menopause is the permanent ceasing of menstruation for one year and in this period, women potentially suffer from chronic signs and symptoms resulted from estrogen deficiency. With respect to heavy responsibility of women in the society, providing their health is highly required by health system. The objective of the current research is the comparison between the effects of Fennel and Hypiran on severity of climacteric symptoms and sexual performance in menopausal women. Methodology: In a blind placebo-controlled clinical trial, 120 menopausal women of 45-60 of age in Shiraz were randomly categorized in three groups after a checkup for general health. The first group was given the daily dose of three 160mg tablets of Hypiran, the second group was given the daily dose of three 30mg tablets of Fennel and the third group was given three placebo all for the period of 8 weeks. The data was collected by filling out questionnaire for female sexual function and Greene climacteric scale in three phases (before treatment, 4weeks after treatment and 8 weeks after treatment. Thus, 33 individuals in Hypiran group, 33 individuals in Fennel group and 32 individuals in placebo group cooperated until the end of the research. The collected data was analyzed by SPSS software (version 20. Findings: The average age of the participants was 50/52. The score of climacteric symptoms was 42/12±5/1 in Hypiran group before treatment and it decreased to 30/42±4/77 after treatment. The score of climacteric symptoms was 37/81±7/2 in Fennel group before treatment and it decreased to 24/93±6/3 after treatment and regardless of the time, there was a significant difference between the three groups (P≤0.001. The score of sexual function was 18/2±2/61 in Hypiran group before treatment and it increased to 22/78±2/61 after treatment. The score of sexual function was 18/38±2/29 in Fennel group before treatment and it increased to 22/51±2/25 after

  11. Community prevention and treatment of female climacteric syndrome%女性更年期综合征的社区防治

    Institute of Scientific and Technical Information of China (English)

    张利燕

    2012-01-01

    更年期综合征是指妇女在围绝经期前后由于卵巢功能逐渐衰退或丧失,激素水平下降而引起的以植物神经功能紊乱、代谢障碍为主的综合征.现今逐渐老龄化的社区,更年期妇女这一庞大的群体出现的生理及心理方面的问题尤为突出,为解决这一社区妇女常见疾患,社区医生采取激素替代疗法、心理疏导、健康教育等综合方法,有效地改善了更年期综合征患者的症状,提高其心理健康水平及生活质量.%Climacteric syndrome refers to a series of symptoms caused by disorders of vegetative nervous system and metabolic system due to hypofunction of ovary in women before and after menopause. At present, the population aging has become serious gradually, and the physiological and psychological disorders of climacteric women are becoming prominent. In order to treat the climacteric syndrome, community doctors carry out the hormone replacement therapy, psychological counseling and health education, effectively improve the syndromes of climacteric women, as well as enhance their mental health and quality of life.

  12. Analysis of Dehydration in the Different Stages of Women Training: Wrestling vs. Judo

    Directory of Open Access Journals (Sweden)

    Bibiana Calvo Rico

    2013-12-01

    Full Text Available This study aimed at analyzing variables concerning body composition and strength affected by dehydration methods used to reach the competition weight in sportswomen (19 women. This study took into account two combat sports (wrestling sample: 11 women and judo sample: 8 women in three different training stages: base, specific and pre-competitive. The assessment tools applied to body composition sizes and strength variables were Inbody 230 and Isocontro 5.0, respectively. Results showed that both wrestling training and judo training in specific and pre-competitive stages were done under water scarcity. Then, the most affected strength variables were: maximum strength and the body composition ones were: weight, percentage of water and body fat. Thus, this research proposed to set some regulations to be applied in reasoned weight loss depending on training goals in order to avoid a disservice to each stage, competition and sportswomen health.

  13. Sanitation, Stress, and Life Stage: A Systematic Data Collection Study among Women in Odisha, India.

    Directory of Open Access Journals (Sweden)

    Kristyna R S Hulland

    Full Text Available Emerging evidence demonstrates how inadequate access to water and sanitation is linked to psychosocial stress, especially among women, forcing them to navigate social and physical barriers during their daily sanitation routines. We examine sanitation-related psychosocial stress (SRPS across women's reproductive lives in three distinct geographic sites (urban slums, rural villages, and rural tribal villages in Odisha, India. We explored daily sanitation practices of adolescent, newly married, pregnant, and established adult women (n = 60 and identified stressors encountered during sanitation. Responding to structured data collection methods, women ranked seven sanitation activities (defecation, urination, menstruation, bathing, post-defecation cleaning, carrying water, and changing clothes based on stress (high to low and level of freedom (associated with greatest freedom to having the most restrictions. Women then identified common stressors they encountered when practicing sanitation and sorted stressors in constrained piles based on frequency and severity of each issue. The constellation of factors influencing SRPS varies by life stage and location. Overall, sanitation behaviors that were most restricted (i.e., menstruation were the most stressful. Women in different sites encountered different stressors, and the level of perceived severity varied based on site and life stage. Understanding the influence of place and life stage on SRPS provides a nuanced understanding of sanitation, and may help identify areas for intervention.

  14. Sanitation, Stress, and Life Stage: A Systematic Data Collection Study among Women in Odisha, India.

    Science.gov (United States)

    Hulland, Kristyna R S; Chase, Rachel P; Caruso, Bethany A; Swain, Rojalin; Biswal, Bismita; Sahoo, Krushna Chandra; Panigrahi, Pinaki; Dreibelbis, Robert

    2015-01-01

    Emerging evidence demonstrates how inadequate access to water and sanitation is linked to psychosocial stress, especially among women, forcing them to navigate social and physical barriers during their daily sanitation routines. We examine sanitation-related psychosocial stress (SRPS) across women's reproductive lives in three distinct geographic sites (urban slums, rural villages, and rural tribal villages) in Odisha, India. We explored daily sanitation practices of adolescent, newly married, pregnant, and established adult women (n = 60) and identified stressors encountered during sanitation. Responding to structured data collection methods, women ranked seven sanitation activities (defecation, urination, menstruation, bathing, post-defecation cleaning, carrying water, and changing clothes) based on stress (high to low) and level of freedom (associated with greatest freedom to having the most restrictions). Women then identified common stressors they encountered when practicing sanitation and sorted stressors in constrained piles based on frequency and severity of each issue. The constellation of factors influencing SRPS varies by life stage and location. Overall, sanitation behaviors that were most restricted (i.e., menstruation) were the most stressful. Women in different sites encountered different stressors, and the level of perceived severity varied based on site and life stage. Understanding the influence of place and life stage on SRPS provides a nuanced understanding of sanitation, and may help identify areas for intervention.

  15. The age and symptomatology of natural menopause among United Arab Emirates women.

    Science.gov (United States)

    Rizk, D E; Bener, A; Ezimokhai, M; Hassan, M Y; Micallef, R

    1998-06-17

    A population-based survey of 742 United Arab Emirates women aged 40 years and over who had attained natural menopause (amenorrhea of at least 6 months' duration) investigated age at onset and the prevalence of climacteric symptoms. Women from both urban and rural areas of Al-Ain City and Abu Dhabi, Dubai, and Sharjah Emirates were recruited through use of the multi-stage stratified cluster sampling technique. The median age at menopause in this sample was 48 years (mean, 47.3 +or- 3.29 years; range, 40-59 years)--significantly lower than the 50.3 year mean recorded among Western women. Median age at menopause was significantly associated with that of the mother (p 0.001) and older sister (p 0.001), parity (p 0.0001), and a history of use of oral contraceptives for more than 1 year (p 0.001). 394 women (53%) reported at least one climacteric symptom. Most common were hot flushes, reported by 47% of women. 145 women (19.5%) were currently taking hormone replacement therapy. The relatively low age at menopause in this population could reflect additional social, economic, environmental, or genetic factors that were not explored in this study.

  16. Survival after early-stage breast cancer of women previously treated for depression

    DEFF Research Database (Denmark)

    Suppli, Nis Frederik Palm; Johansen, Christoffer; Kessing, Lars Vedel

    2017-01-01

    Purpose The aim of this nationwide, register-based cohort study was to determine whether women treated for depression before primary early-stage breast cancer are at increased risk for receiving treatment that is not in accordance with national guidelines and for poorer survival. Material...... and Methods We identified 45,325 women with early breast cancer diagnosed in Denmark from 1998 to 2011. Of these, 744 women (2%) had had a previous hospital contact (as an inpatient or outpatient) for depression and another 6,068 (13%) had been treated with antidepressants. Associations between previous...... treatment of depression and risk of receiving nonguideline treatment of breast cancer were assessed in multivariable logistic regression analyses. We compared the overall survival, breast cancer-specific survival, and risk of death by suicide of women who were and were not treated for depression before...

  17. Investigation in climacteric symptoms and depression of gynaecology outpatients and inpatients%妇科门诊和住院患者更年期症状与抑郁的调查分析

    Institute of Scientific and Technical Information of China (English)

    张媛园; 周彩峰; 付文君

    2011-01-01

    Objective To investigate the climacteric symptoms and depressive related factors of climacteric females in gynecology outpatients and inpatients,to provide evidence for effective health promotion.Methods 416 climacteric women were investigated by using improved menopause Kuppermen Scales and Center for Epidemiological Studies Depression (CES-D).The results underwent analysis.Results There were 93.99% of patients suffering from climacteric syndrome,49.52% with depression symptom.The main factors of climacteric syndrome were eating breakfast according to the timetable every day,nutritionally balanced diet,controlling of salt intake,regular body exercises and to maintain a proper body weight.Factors related to depression symptoms were sore breasts,constipation,dry skin,lower abdominal pain.The correlation between climacteric syndrome and depressive symptom was significant.Conclusions The main influencing factor of climacteric syndrome was healthy lifestyle.The climacteric syndrome increases the risk of depressive symptoms.%目的 调查女性更年期症状与抑郁的影响因素,为促进健康提供依据.方法 采用改良更年期Kupperman评分量表和流行病学调查用抑郁自评量表(center for epidemiological studiesdepression,CES-D),对416例更年期女性进行调查,并对结果进行分析.结果 更年期综合征的发生率高达93.99%,抑郁发生率达49.52%.按时每天吃早餐、营养平衡的饮食、控制盐分摄入、定期锻炼身体及维持适当体质量,这5项健康生活因素是更年期综合征的主要影响因素.乳房疼痛、便秘、皮肤干燥、下腹部疼痛,这4项抑郁相关症状因素和更年期女性抑郁存在显著相关.更年期综合征和抑郁症状之间存在显著相关.结论 健康的生活方式是更年期症状的主要影响因素,更年期症状增加了抑郁症状的发生危险.

  18. Experimental Study of Angeng Prescription for Climacteric Syndrome in Rats

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    CHEN Da-shuai

    2014-12-01

    Full Text Available Objective: To observe the effect of Angeng Formula on climacteric syndrome in rats. Methods: The ovaries of female SD rats were removed for the establishment of menopausal syndrome rat models. After drug delivery for 30 d, serum sex hormone levels and indexes of uterus, adrenal gland and pituitary were detected. Meanwhile, the effects of drugs on the histopathology of uterus, adrenal gland and pituitary in rats were observed. Results: Angeng prescription could increase the level of estradiol (E2 in castrated rat (P<0.01 and had a tendency to increase the level of progestin (P, lower the level of luteinizing hormone (LH and follicle-stimulating hormone (FSH as well as increase the indexes of the uterus and adrenal gland. Moreover, Angeng prescription could improve the pathologic condition of the uterus, adrenal gland and pituitary in castrated rats. Conclusion: Angeng prescription has a therapeutic effect on climacteric syndrome, the mechanism of which might be related with the function of regulating sex hormone.

  19. Experimental Study on Angeng Formula for Climacteric Syndrome in Rats

    Institute of Scientific and Technical Information of China (English)

    CHEN Da-shuai; LI Peng-li; TAN Hai-zhi

    2014-01-01

    Objective:To observe the effect of Angeng Formula on climacteric syndrome in rats. Methods:The ovaries of female SD rats were removed for the establishment of menopausal syndrome rat models. After drug delivery for 30 d, serum sex hormone levels and indexes of uterus, adrenal gland and pituitary were detected. Meanwhile, the effects of drugs on the histopathology of uterus, adrenal gland and pituitary in rats were observed. Results:Angeng Formula could increase the level of estradiol (E2) in castrated rat (P<0.01) and had a tendency to increase the level of progestin (P), lower the level of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) as well as increase the indexes of the uterus and adrenal gland. Moreover, Angeng Formula could improve the pathologic condition of the uterus, adrenal gland and pituitary in castrated rats. Conclusion:Angeng Formula has a therapeutic effect on climacteric syndrome, the mechanism of which might be related with the function of regulating sex hormone.

  20. Acupuncture compares with Western medicine for climacteric depression

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    Quan Xiao Hong

    2016-04-01

    Full Text Available The aim of this study was to assess the clinical efficacy and safety of acupuncture for climacteric depression. Two reviewers searched major databases independently. The quality assessment and data analysis were evaluated by Cochrane reviews 5.3.0. Seventeen clinical trials were included, contained 1,369 cases. Meta-analysis of acupuncture comparing with medicine showed that: a Affective rate: [OR = 1.44, 95% CI (1.02, 2.04], the difference had statistically significance; b HAMA score : [MD = -2.12, 95% CI (-2.85, -1.40], the difference had statistically significance; c HAMD score: The difference of the 2nd week, 4th week, 6th week, 8th week, or 12th week was not statistically significant; d Kupperman score: [MD = -5.05, 95% CI (-11.94, 1.84] showed no statistical significance; e Incidence of adverse events of acupuncture (2.7% was significantly less than the control group (20%. In conclusion acupuncture will help to improve depressive symptoms of climacteric and decrease adverse reactions.

  1. Women's steps of change and entry into drug abuse treatment. A multidimensional stages of change model.

    Science.gov (United States)

    Brown, V B; Melchior, L A; Panter, A T; Slaughter, R; Huba, G J

    2000-04-01

    The Transtheoretical, or Stages of Change Model, has been applied to the investigation of help-seeking related to a number of addictive behaviors. Overall, the model has shown to be very important in understanding the process of help-seeking. However, substance abuse rarely exists in isolation from other health, mental health, and social problems. The present work extends the original Stages of Change Model by proposing "Steps of Change" as they relate to entry into substance abuse treatment programs for women. Readiness to make life changes in four domains-domestic violence, HIV sexual risk behavior, substance abuse, and mental health-is examined in relation to entry into four substance abuse treatment modalities (12-step, detoxification, outpatient, and residential). The Steps of Change Model hypothesizes that help-seeking behavior of substance-abusing women may reflect a hierarchy of readiness based on the immediacy, or time urgency, of their treatment issues. For example, women in battering relationships may be ready to make changes to reduce their exposure to violence before admitting readiness to seek substance abuse treatment. The Steps of Change Model was examined in a sample of 451 women contacted through a substance abuse treatment-readiness program in Los Angeles, California. A series of logistic regression analyses predict entry into four separate treatment modalities that vary. Results suggest a multidimensional Stages of Change Model that may extend to other populations and to other types of help-seeking behaviors.

  2. Stage-specific education/counseling intervention in women with elevated blood pressure.

    Science.gov (United States)

    Daley, Linda K; Fish, Anne F; Frid, David J; Mitchell, G Lynn

    2009-06-01

    Many women with elevated blood pressure who seek exercise opportunities require a flexible program with systematic follow-up. The study framework included motivational readiness (exercise stage of change) from the Transtheoretical Model and self-efficacy theory. This pilot study, which used a one-group repeated measures design, tested the feasibility of a stage-specific education/counseling intervention aimed at improving exercise outcomes in women with elevated blood pressure. Forty women completed a 2.5-hour session including prescription for moderate-vigorous exercise on their own, practice on equipment, maintenance of an exercise diary, and contracting; three follow-up calls (Weeks 1, 2, 3); a visit (Week 4); and a final call (Week 5). After the intervention, 85% of women moved to or remained in the action or maintenance stages of change, the highest levels of readiness; none relapsed. Exercise self-efficacy and benefits increased and barriers decreased (Pexercise performance. The intervention was feasible. Further testing is warranted using larger samples and including a control group.

  3. Promising clinical practices of metformin in women with PCOS and early-stage endometrial cancer

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    Ruijin Shao

    2014-12-01

    Full Text Available Young women with polycystic ovary syndrome (PCOS have a high risk of developing endometrial cancer (EC. There is an urgent need for non-surgical prevention and treatment strategies for these patients who fail to respond to progesterone treatment and wish to preserve their fertility. Recently, we have reported that the combined treatment with metformin and progesterone-based oral contraceptives has successfully reversed the early-stage EC into normal endometria in addition to improvement of insulin resistance in women with PCOS. More importantly, one of these treated women has successfully delivered a healthy newborn baby. However, before such treatment can be recommended to the clinical practice, the molecular basis of metformin in the endometrium under physiological and pathological conditions must be elucidated.

  4. Reproduction in women with end-stage renal disease and effect of kidney transplantation.

    Science.gov (United States)

    Ghazizadeh, Shirin; Lessan-Pezeshki, Mahboob

    2007-07-01

    Menstrual problem is common among women with chronic kidney disease, and patients with end-stage renal disease usually have amenorrhea. The rate of pregnancy in women on dialysis is low. Fetal survival in this population has improved, with half of such pregnancies resulting in delivery of a live infant. However, prematurity remains common and accounts for the low-birth weight of these infants. Intensifying hemodialysis by increasing the frequency of treatments is associated with longer gestation and increased likelihood of a successful pregnancy. Intense hemodialysis also improves the control of maternal intravascular volume and reduces the risk of hypotension due to excessive ultrafiltration. Women with chronic kidney disease tend to experience decreased libido and reduced ability to reach orgasm. Sexual difficulties in uremic patients are often worsened by hemodialysis, with a lowered frequency of intercourse, reduced sexual desire, and an increased incidence of sexual failure. There have been ongoing improvements in survival and quality of life after kidney transplantation. In most patients, sexual desire increases significantly after successful transplantation; however, improvement in the frequency of sexual activity and the overall sexual satisfaction is not as high as that in sexual desire. These have been accompanied by an improvement in reproductive function. Pregnancy success rate exceeds 90% after the first trimester in women with kidney transplant. Contraceptive counseling should be provided before transplantation, because ovulatory cycles may begin within 1 to 2 months after transplantation in women with functioning grafts. Breastfeeding is discouraged for patients taking any immunosuppressive drugs.

  5. Efeito de um programa misto de intervenção nutricional e exercício físico sobre a composição corporal e os hábitos alimentares de mulheres obesas em climatério The effects of a mixed program of nutritional intervention and physical exercise on body composition and feeding habits of obese climacteric women

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    Rita de Cássia de Assunção Monteiro

    2004-12-01

    Full Text Available OBJETIVO: Foi avaliar o efeito de programa misto de intervenção nutricional e exercício físico sobre a composição corporal e hábitos alimentares de mulheres obesas em climatério. MÉTODOS: Trabalhou-se com 2 grupos de 15 pessoas por 40 semanas: Grupo Dieta (intervenção nutricional e Grupo Exercício (intervenção nutricional e exercício. RESULTADO: As reduções do peso (-2,3kg para Grupo Dieta e -5,3kg para o Grupo Exercício e da circunferência da cintura (-4,8cm para Grupo Dieta e -7,6cm para Grupo Exercício, foram maiores para o Grupo Exercício. Foi verificada evolução positiva na classificação do Índice de Massa Corporal para ambos os grupos, sendo que o Grupo Exercício respondeu melhor ao tratamento. O padrão alimentar foi considerado monótono e com baixo consumo de alimentos regionais. CONCLUSÃO: O programa foi efetivo para perda de peso, em maior intensidade na presença de exercício. A educação alimentar proposta foi capaz de acarretar mudanças nos hábitos alimentares.OBJECTIVE: The effects of a mixed program of nutrition intervention and physical exercise on body composition and feeding habits were evaluated in obese climacteric women. METHODS: Thirty participants were randomly assigned in 2 groups during 40 weeks: Diet Group (nutritional intervention and Exercise Group (nutritional intervention and exercise. RESULTS: Weight reductions (Diet Group 2,3kg/Exercise Group -5,3kg and waist circunference (Diet Group -4,8cm/Exercise Group 7,6cm were greater in Exercise Group. A positive evolution was noticed in the Body Mass Index in both groups, with Exercise Group having better answer to treatment. It was observed a monotonous feeding pattern and low compliance to the consumption of regional typical foods. CONCLUSION: We concluded that the program was effective for weight loss at a higher intensity in the presence of exercise and the feeding education was able to modify the feeding habits.

  6. Validación de un cuestionario para la medición de las creencias sobre el climaterio Validity test of a questionnaire used to measure climacteric beliefs

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    Rubén Chávez-Ayala

    2002-09-01

    Full Text Available Objetivo. Diseñar un instrumento para medir las creencias sobre las consecuencias sociales, psicológicas y fisiológicas de la etapa del climaterio. Material y métodos. El estudio se realizó de junio a octubre de 2000 en 340 mujeres derechohabientes de la unidad de medicina familiar del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (media de edad=49.46, (DE 7.92. Se seleccionó un total de mujeres entre los 40 y 60 años de edad, en virtud del criterio de la Organización Mundial de la Salud: el promedio de edad de la menopausia es de 50 años. El promedio de embarazos en la muestra fue de 3.75 (DE 2.57, y el de hijos nacidos de 3.21 (DE 2.19. El 48.3% de las mujeres eran premenopáusicas, 10.9% perimenopáusicas y 40.6% posmenopáusicas. El instrumento contó con 25 reactivos, y la escala utilizada para evaluar las respuestas fue de tipo Likert con cinco opciones. El tipo de diseño fue observacional exploratorio, de corte transversal multivariado. Se hicieron comparaciones de medias por factor entre los grupos de mujeres premenopáusicas, perimenopáusicas y posmenopáusicas. Resultados. Se realizó un análisis factorial con rotación Varimax, confirmándose cuatro factores: desventajas, (alfa=0.769; ventajas, (alfa=0.839; fisiológico, (alfa=0.659, y psicológico, (alfa=0.711. Conclusiones. El presente instrumento tiene una buena consistencia interna, y mide cuatro grupos de creencias sobre el climaterio: a creencias de desventajas, b creencias de ventajas, c creencias sobre padecimientos fisiológicos, y d creencias de síntomas psicológicos. Las tres dimensiones confirmadas del climaterio han sido propuestas en otros estudios.Objective. To design an instrument for measuring beliefs about the social, psychological, and physiological consequences of women's climacteric stage. Material and Methods. The study included 340 women affiliated to Instituto de Seguridad y Servicios Sociales para los Trabajadores del

  7. Morbidades e fatores associados em mulheres climatéricas: estudo de base populacional em mulheres com 11 anos ou mais de escolaridade Morbidity and associated factors in climacteric women: a population based study in women with 11 or more years of formal education

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    Vanessa de Souza Santos Machado

    2012-05-01

    Full Text Available OBJETIVO: Avaliar os fatores associados a algumas morbidades em mulheres brasileiras de 40 a 65 anos e com 11 anos ou mais de escolaridade. MÉTODOS: Análise secundária de estudo transversal de base populacional, empregando-se um questionário anônimo e autorrespondido por 377 mulheres. Foram avaliadas, com o uso deste instrumento, algumas morbidades (hipertensão, diabetes, insônia e depressão e fatores sociodemográficos, comportamentais, clínicos e reprodutivos. A associação entre as morbidades e as variáveis independentes foi avaliada por meio do teste do Χ2. Realizou-se a regressão logística múltipla com critério de seleção stepwise para selecionar os principais fatores associados a cada uma das morbidades. RESULTADOS: Na análise múltipla, a insônia esteve associada à autopercepção da saúde péssima/ruim (OR=2,3 e ao nervosismo (OR=5,1. O relato de depressão esteve associado à autopercepção da saúde péssima/ruim (OR=3,7 e ter lazer péssimo/ruim (OR=2,8. A hipertensão apresentou-se relacionada à obesidade (OR=3,1 e a estar na pós-menopausa (OR=2,6. Já diabetes, à idade acima de 50 anos (OR=3,9 e obesidade à (OR=12,5. CONCLUSÕES: A prevalência de morbidades foi alta e pior autopercepção da saúde e obesidade foram os principais fatores associados à presença de morbidades.PURPOSE: To evaluate factors associated with morbidities among Brazilian women aged 40-65 years and with 11 or more years of schooling. METHODS: A secondary analysis of a cross-sectional population-based study was conducted, using an anonymous self-report questionnaire completed by 377 women. Were evaluated, with this instrument, some morbidities (hypertension, diabetes, insomnia and depression and sociodemographic, behavioral, clinical and reproductive factors. The association between morbidities and independent variables was evaluated by the Χ2 test. Multiple logistic regression analysis with stepwise selection criteria was used to

  8. Analysis of Clinical Treatment Efficiency for 179 Geriatric Women with Stage I or II Cervical Carcinoma

    Institute of Scientific and Technical Information of China (English)

    YongwenHuang; MengdaLi; FuyuanLiu; YanfangLi

    2004-01-01

    OBJECTIVE To evaluate the efficiency of surgery plus radiotherapy and chemotherapy versus radiotherapy plus chemotherapy in the treatment of older patients with stage I or II cervical carcinoma and to seek suitable treatment for such patients. METHODS The clinical data of 179 elderly women with stage la or lib cervical cancer were analyzed retrospectively. One hundred and thirty-four cases underwent radical hysterectomy followed by adjuvant radiotherapy and/or chemotherapy (Group 1). Forty-five cases underwent radiation therapy plus adjuvant chemotherapy (Group 2). RESULTS The 5-year survival rates in group 1 and group 2 were 78.3% and 49.1%(P=0.04), respectively. The incidence of complications in group1 was 47.0%. Three patients died of complications after radical hysterectomy. The incidence of complications in group 2 was 75.6%. CONCLUSION Elderly patients with stage I or II cervical carcinoma should receive an operation if possible. In addition they should receive adjuvant treatments according to their personal conditions, and be treated with appropriate adjuvant chemo-and/or radiotherapy.

  9. Association between persistence with mammography screening and stage at diagnosis among elderly women diagnosed with breast cancer.

    Science.gov (United States)

    Vyas, Ami; Madhavan, Suresh; Sambamoorthi, Usha

    2014-12-01

    Previous studies on the association between mammography screening and stage at breast cancer (BC) diagnosis have limitations because they did not analyze persistence with mammography screening and did not distinguish screening from diagnostic mammograms. The objective of this study is to determine the association between persistence with mammography screening and stage at BC diagnosis among elderly women. A retrospective observational study of 39,006 women age ≥70 diagnosed with incident BC from 2005 to 2009 from the Surveillance, Epidemiology, and End Results (SEER)-Medicare dataset was conducted. A validated algorithm with high sensitivity and specificity was used to distinguish between screening and diagnostic mammograms. Persistence with mammography screening was measured as having at least three screening mammograms in five years before BC diagnosis. Multinomial logistic regressions were performed to analyze the association between persistence with mammography screening and stage at diagnosis, in a multivariate framework. Overall, 46% of elderly women were persistent with mammography screening, 26% were not persistent, and 28% did not have any screening mammogram in five years before BC diagnosis. As compared to women who were not persistent with mammography screening, women who were persistent with mammography screening were significantly more likely to be diagnosed at earlier stages of BC. The adjusted odds ratios were 3.28, 2.37, and 1.60 for in situ, local, and regional stages, respectively. A lower proportion of elderly women was persistent with mammography and it was highly associated with earlier stages of BC diagnosis. Interventions designed to promote persistent mammography screening among elderly women are warranted.

  10. Perceived barriers to exercise and stage of exercise adoption in older women of different racial/ethnic groups.

    Science.gov (United States)

    Heesch, K C; Brown, D R; Blanton, C J

    2000-01-01

    The purpose of this study was to determine whether barriers to exercise differ among racial/ethnic groups at the same stage of exercise adoption and adjacent stages within racial/ethnic groups. Questions about stage of exercise adoption and perceived barriers to exercise were administered to a cross sectional sample of 745 African American, 660 Hispanic, 738 Native American/Native Alaskan, and 769 Caucasian U.S. women aged 40 years and older. Correlations between rankings of barriers among racial/ethnic groups within the same stage ranged from .43 to .89. For each racial/ethnic group, significant differences existed between adjacent stages in the percentage of women reporting barriers to interfere with exercise (p < .10). Barriers were not similar enough among racial/ethnic groups to recommend that the same barriers be addressed for all races/ethnicities.

  11. Robotic-assisted laparoscopic hysterectomy seems safe in women with early-stage endometrial cancer

    DEFF Research Database (Denmark)

    Herling, Suzanne Forsyth; Havemann, Maria Cecilie; Palle, Connie

    2015-01-01

    INTRODUCTION: Robotic surgery is increasingly used in the management of endometrial cancer; and although it is known that minimally invasive surgery reduces post-operative morbidity, the outcomes of this novel treatment should be monitored carefully. The aim of this study was to examine...... the incidence of complications according to the Clavien-Dindo scale after robotic-assisted laparoscopic hysterectomy (RALH) for early-stage endometrial cancer and atypical complex hyperplasia. The Clavien-Dindo scale grades the severity of complications. METHODS: This was a retrospective, descriptive cohort...... study of 235 women with endometrial cancer or atypical complex hyperplasia who had RALH. Surgeries were stratified into two groups: with or without pelvic lymphadenectomy. RESULTS: A total of 6% developed a grade 3 or higher complication with no significant difference (p = 0.24) between the groups...

  12. The Experience of Robotic-Assisted Laparoscopic Hysterectomy for Women Treated for Early-Stage Endometrial Cancer

    DEFF Research Database (Denmark)

    Herling, Suzanne Forsyth; Palle, Connie; Moeller, Ann M

    2016-01-01

    BACKGROUND: An increasing number of women are offered robotic-assisted laparoscopic hysterectomy as treatment for early-stage endometrial cancer in the developed world. OBJECTIVE: The aim of this study was to explore how women diagnosed with early-stage endometrial cancer experienced robotic......-assisted laparoscopic hysterectomy. METHODS: Semistructured interviews were carried out with 12 women, and interview data were analyzed by qualitative content analysis. RESULTS: Four overarching themes emerged: "surgery was a piece of cake," "recovering physically after surgery," "going from being off guard to being...... on guard," and "preparing oneself by seeking information." The women had confidence in the robotic technique and experienced fast recovery after robotic-assisted laparoscopic hysterectomy; however, they had uncertainties and unanswered questions concerning the postoperative course. Shortly after discharge...

  13. Limited Engagements? Women's and Men's Work/Volunteer Time in the Encore Life Course Stage.

    Science.gov (United States)

    Moen, Phyllis; Flood, Sarah

    2013-05-01

    Americans are living healthier and longer lives, but the shifting age distribution is straining existing and projected social welfare protections for older adults (e.g., Social Security, Medicare). One solution is to delay retirement. Another is an alternative to "total leisure" retirement -- an "encore" stage of paid or unpaid engagement coming after career jobs but before infirmities associated with old age. We draw on gendered life-course themes together with data from the American Time Use Survey (2003-2009) to examine the real time American men and women ages 50-75 apportion to paid work and unpaid volunteer work on an average day, as well as factors predicting their time allocations. We find that while full-time employment declines after the 50s, many Americans allot time to more limited engagements - working part time, being self-employed, volunteering, helping out - through and even beyond their 60s. Caring for a child or infirm adult reduces the odds of paid work but not volunteering. While time working for pay declines with age (though more slowly for men than women), time volunteering does not. Older men and women in poor health, without a college degree, with a disability or SSI income are the least likely to be publicly engaged. This social patterning illustrates that while the ideal of an encore of paid or unpaid voluntary, flexible, and meaningful engagement is an emerging reality for some, it appears less attainable for others. This suggests the importance of organizational and public policy innovations offering all Americans a range of encore opportunities.

  14. HPV16 variant lineage, clinical stage, and survival in women with invasive cervical cancer

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    Zuna Rosemary E

    2011-10-01

    Full Text Available Abstract Background HPV16 variants are associated with different risks for development of CIN3 and invasive cancer, although all are carcinogenic. The relationship of HPV 16 variants to cancer survival has not been studied. Methods 155 HPV16-positive cervical cancers were categorized according to European and non-European variant patterns by DNA sequencing of the E6 open reading frame. Clinico-pathologic parameters and clinical outcome were collected by chart review and death registry data. Results Of the 155 women (mean age 44.7 years; median follow-up 26.7 months, 85.2% harbored European variants while 14.8% had non-European sequences. HPV16 variants differed by histologic cell type (p = 0.03 and stage (1 vs. 2+; p = 0.03. Overall, 107 women (68.0% were alive with no evidence of cancer, 42 (27.1% died from cervical cancer, 2 (1.3% were alive with cervical cancer, and 4 (2.6% died of other causes. Death due to cervical cancer was associated with European variant status (p Conclusions Overall, invasive cervical cancers with non-European variants showed a less aggressive behavior than those with European variants. These findings should be replicated in a population with more non-European cases.

  15. Advanced Imaging and Receipt of Guideline Concordant Care in Women with Early Stage Breast Cancer

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    Elizabeth Trice Loggers

    2016-01-01

    Full Text Available Objective. It is unknown whether advanced imaging (AI is associated with higher quality breast cancer (BC care. Materials and Methods. Claims and Surveillance Epidemiology and End Results data were linked for women diagnosed with incident stage I-III BC between 2002 and 2008 in western Washington State. We examined receipt of preoperative breast magnetic resonance imaging (MRI or AI (defined as computed tomography [CT]/positron emission tomography [PET]/PET/CT versus mammogram and/or ultrasound (M-US alone and receipt of guideline concordant care (GCC using multivariable logistic regression. Results. Of 5247 women, 67% received M-US, 23% MRI, 8% CT, and 3% PET/PET-CT. In 2002, 5% received MRI and 5% AI compared to 45% and 12%, respectively, in 2008. 79% received GCC, but GCC declined over time and was associated with younger age, urban residence, less comorbidity, shorter time from diagnosis to surgery, and earlier year of diagnosis. Breast MRI was associated with GCC for lumpectomy plus radiation therapy (RT (OR 1.55, 95% CI 1.08–2.26, and p=0.02 and AI was associated with GCC for adjuvant chemotherapy for estrogen-receptor positive (ER+ BC (OR 1.74, 95% CI 1.17–2.59, and p=0.01. Conclusion. GCC was associated with prior receipt of breast MRI and AI for lumpectomy plus RT and adjuvant chemotherapy for ER+ BC, respectively.

  16. Reference intervals for common thyroid function tests, during different stages of pregnancy in Chinese women

    Institute of Scientific and Technical Information of China (English)

    FAN Jian-xia; HAN Mi; TAO Jun; LUO Jun; SONG Meng-fan; YANG Shuai; KHOR Shu-zin

    2013-01-01

    Background The importance of diagnosis of thyroid dysfunction during pregnancy has been widely recognized.Our study was designed to compare two different detection reagents between Abbott and Roche and to establish the gestational-related reference intervals for thyroid function tests (TFT) in Chinese women and to assay the reference ranges with the American Thyroid Association recommended standard.Methods Serum samples were collected from 693 normal pregnant Chinese women and divided into five groups according to their gestational age:9-13,16-20,24-28,32-34 and 37-40 weeks.Thyroid stimulating hormone (TSH) and free thyroxine (FT4) levels were determined by two different detection reagents:Abbott Architect l 2000 and Roche Cobas Elecsys 600.The reference ranges of the TFT indexes were calculated according to the National Academy of Clinical Biochemistry (NACB).The 2.5th and 97.5th percentiles of each stage were calculated,and the results were analyzed by one-way analysis of variances,t-test,and Spearman correlation analysis.Results Thyroid hormone levels varied greatly among different gestational stages.TSH levels,as assessed via two different TSH ELISA kits showed consistent changing pattern during pregnancy and displayed linear correlation (P <0.001).In 9-13 gestational weeks,TSH levels were significantly lower than that of other groups; and in 37-40 gestational weeks,it was higher than that of other groups (all P <0.001).TSH reference ranges determined by Roche detection reagent in each group were higher than those by Abbott detection reagent (P <0.01 respectively).FT4 levels were higher in 9-13 gestational weeks than that of other groups (P <0.001).FT4 levels determined by Roche reagent were higher than Abbott reagent in 9-13 weeks,(P <0.001),and lower in 24-28 and 37-40 weeks (P <0.001 and P=0.016,respectively).The TSH level was correlated with FT4 levels in 9-13 gestational weeks by detection reagents (for Abbott reagent,r=-0.319 for FT4 P <0

  17. Robotic-assisted laparoscopic hysterectomy seems safe in women with early-stage endometrial cancer

    DEFF Research Database (Denmark)

    Herling, Suzanne Forsyth; Havemann, Maria Cecilie; Palle, Connie;

    2015-01-01

    INTRODUCTION: Robotic surgery is increasingly used in the management of endometrial cancer; and although it is known that minimally invasive surgery reduces post-operative morbidity, the outcomes of this novel treatment should be monitored carefully. The aim of this study was to examine the incid......INTRODUCTION: Robotic surgery is increasingly used in the management of endometrial cancer; and although it is known that minimally invasive surgery reduces post-operative morbidity, the outcomes of this novel treatment should be monitored carefully. The aim of this study was to examine...... the incidence of complications according to the Clavien-Dindo scale after robotic-assisted laparoscopic hysterectomy (RALH) for early-stage endometrial cancer and atypical complex hyperplasia. The Clavien-Dindo scale grades the severity of complications. METHODS: This was a retrospective, descriptive cohort....... CONCLUSION: The types and frequency of complications observed in this study resemble those reported in similar studies of RALH for malignant gynaecologic conditions. Health-care professionals treating and caring for women with early-stage endometrial cancer should know of the types and frequency of post...

  18. Stage of change is associated with assessment of the health risks of maternal smoking among pregnant women.

    Science.gov (United States)

    Haslam, C; Draper, E

    2000-10-01

    This study explored pregnant women's assessment of the health risks associated with maternal smoking. The aim was to determine if stage of change relating to smoking is associated with risk assessment. A cross-sectional survey (employing a self-completion questionnaire) was conducted of all women who attended antenatal clinics at Leicester Royal Infirmary, National Health Service Trust, UK over a 2 week period. Questionnaires were completed by 254 respondents. Twenty seven percent of non-smokers agreed with more than 75% of a series of statements about the dangers of maternal smoking compared to 5% of smokers and 44% of women in social class I (highest social class) agreed with more than 75% of the statements compared with only 10% of women in social classes IV and V (lower social class groups). Married women were twice as likely to concur with more than 75% of the health risks compared to single or cohabiting women and 29% of women intending to breastfeed agreed with more than 75% of the statements compared with only 8.7% of women not intending to breastfeed. There was no significant effect of age, whether the pregnancy was planned, previous obstetric complications or whether the woman had a child with asthma or respiratory infections. A multiple regression analysis indicated that smokers were much less likely to agree with the health risks than their non-smoking counterparts (p = 0.034). Stage of change was related to both the number of health risks agreed with and the level of conviction. A woman's stage of change could be assessed at the start of antenatal care so that appropriate smoking cessation advice can be offered.

  19. Plasma oxidative stress parameters in men and women with early stage Alzheimer type dementia.

    Science.gov (United States)

    Puertas, M C; Martínez-Martos, J M; Cobo, M P; Carrera, M P; Mayas, M D; Ramírez-Expósito, M J

    2012-08-01

    It is well known that oxidative stress is one of the earliest events in Alzheimer's disease pathogenesis, indicating that may play a key role in this disease. In our study, we measured the levels of oxidative stress indicators (TBARS and protein carbonyls content) and the non-enzymatic (glutathione (GSH) and oxidized glutathione (GSSG)) and enzymatic (glutathione peroxidase (GPx), catalase (CAT) and superoxide dismutase (SOD)) defense systems in the plasma of 46 patients diagnosed of ATD and 46 age-matched controls. We found decreased levels in total GSH in ATD patients, although healthy control women showed lower levels of total GSH than healthy control men. On the contrary, we found increased levels of TBARS and carbonyl groups content in ATD patients in both genders. The activity of the plasma antioxidant enzymes showed no changes for SOD activity in ATD patients, independently of the gender, although western blot analysis showed an increase in SOD-1 protein. CAT activity was also decreased in ATD patients, although this decrease is mainly due to the decrease found in men but not in women. However, western blot analysis did not show differences in CAT protein between controls and ATD patients. Finally, a decrease of GPx activity was found in ATD patients in both genders. However, as with CAT protein, western blot analysis did not show differences in GPx protein between controls and ATD patients. Our results suggest that there is a defect in the antioxidant defense system that is incapable of responding to increased free radical production, which may lead to oxidative damage and the development of the pathological alterations that characterize the neurodegenerative disorder of patients with ATD. Thus, oxidative damage could be one important aspect for the onset of ATD and oxidative stress markers could be useful to diagnose the illness in their earliest stages through both non-invasive, reliable and cost-affordable methods.

  20. Uterine electromyography for identification of first-stage labor arrest in term nulliparous women with spontaneous onset of labor

    NARCIS (Netherlands)

    Vasak, Blanka; Graatsma, Elisabeth M.; Hekman-Drost, Elske; Eijkemans, Marinus J.; van Leeuwen, Jules H. Schagen; Visser, Gerard H.; Jacod, Benoit C.

    2013-01-01

    OBJECTIVE: We sought to study whether uterine electromyography (EMG) can identify inefficient contractions leading to first-stage labor arrest followed by cesarean delivery in term nulliparous women with spontaneous onset of labor. STUDY DESIGN: EMG was recorded during spontaneous labor in 119 nulli

  1. Personality predicts perceived availability of social support and satisfaction with social support in women with early stage breast cancer

    NARCIS (Netherlands)

    B.L. den Oudsten; G.L. van Heck; A.F.W. van der Steeg; J.A. Roukema; J. de Vries

    2010-01-01

    This study examines the relationships between personality, on the one hand, and perceived availability of social support (PASS) and satisfaction with received social support (SRSS), on the other hand, in women with early stage breast cancer (BC). In addition, this study examined whether a stressful

  2. Guests line the stage at a women's forum at the Apollo/Saturn V Center

    Science.gov (United States)

    1999-01-01

    At a women's forum about 'Past, Present and Future of Space,' held in the Apollo/Saturn V Center, guests line the stage. From left, they are Marta Bohn-Meyer, the first woman to pilot an SR- 71; astronauts Ellen Ochoa, Ken Cockrell, Joan Higginbotham, and Yvonne Cagle; former astronaut Sally Ride, the first American woman to fly in space; and Jennifer Harris, the Mars 2001 Operations System Development Manager at the Jet Propulsion Laboratory. The forum included a welcome by Center Director Roy Bridges and remarks by Donna Shalala, secretary of Department of Health and Human Services. The attendees are planning to view the launch of STS-93 at the Banana Creek viewing site. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. Liftoff is scheduled for July 20 at 12:36 a.m. EDT.

  3. Efficacy of Cimicifuga racemosa, Hypericum perforatum and Agnus castus in the treatment of climacteric complaints : a systematic review

    NARCIS (Netherlands)

    Laakmann, Elena; Grajecki, Donata; Doege, Katja; Eulenburg, Christine Zu; Buhling, Kai J.

    2012-01-01

    Objective: The systematic review examines whether Cimicifuga racemosa (CR), Hypericum perforatum (HP), Agnus castus, vitamins and minerals, either as monotherapy or in combination, have an evidence-based impact on vasomotor, genital and psychological climacteric complaints. Data sources and methods

  4. Male microchimerism at high levels in peripheral blood mononuclear cells from women with end stage renal disease before kidney transplantation.

    Directory of Open Access Journals (Sweden)

    Laetitia Albano

    Full Text Available Patients with end stage renal diseases (ESRD are generally tested for donor chimerism after kidney transplantation for tolerance mechanism purposes. But, to our knowledge, no data are available on natural and/or iatrogenic microchimerism (Mc, deriving from pregnancy and/or blood transfusion, acquired prior to transplantation. In this context, we tested the prevalence of male Mc using a real time PCR assay for DYS14, a Y-chromosome specific sequence, in peripheral blood mononuclear cells (PBMC from 55 women with ESRD, prior to their first kidney transplantation, and compared them with results from 82 healthy women. Male Mc was also quantified in 5 native kidney biopsies obtained two to four years prior to blood testing and in PBMC from 8 women collected after female kidney transplantation, several years after the initial blood testing. Women with ESRD showed statistically higher frequencies (62% and quantities (98 genome equivalent cells per million of host cells, gEq/M of male Mc in their PBMC than healthy women (16% and 0.3 gEq/M, p<0.00001 and p = 0.0005 respectively. Male Mc was increased in women with ESRD whether they had or not a history of male pregnancy and/or of blood transfusion. Three out of five renal biopsies obtained a few years prior to the blood test also contained Mc, but no correlation could be established between earlier Mc in a kidney and later presence in PBMC. Finally, several years after female kidney transplantation, male Mc was totally cleared from PBMC in all women tested but one. This intriguing and striking initial result of natural and iatrogenic male Mc persistence in peripheral blood from women with ESRD raises several hypotheses for the possible role of these cells in renal diseases. Further studies are needed to elucidate mechanisms of recruitment and persistence of Mc in women with ESRD.

  5. Male microchimerism at high levels in peripheral blood mononuclear cells from women with end stage renal disease before kidney transplantation.

    Science.gov (United States)

    Albano, Laetitia; Rak, Justyna M; Azzouz, Doua F; Cassuto-Viguier, Elisabeth; Gugenheim, Jean; Lambert, Nathalie C

    2012-01-01

    Patients with end stage renal diseases (ESRD) are generally tested for donor chimerism after kidney transplantation for tolerance mechanism purposes. But, to our knowledge, no data are available on natural and/or iatrogenic microchimerism (Mc), deriving from pregnancy and/or blood transfusion, acquired prior to transplantation. In this context, we tested the prevalence of male Mc using a real time PCR assay for DYS14, a Y-chromosome specific sequence, in peripheral blood mononuclear cells (PBMC) from 55 women with ESRD, prior to their first kidney transplantation, and compared them with results from 82 healthy women. Male Mc was also quantified in 5 native kidney biopsies obtained two to four years prior to blood testing and in PBMC from 8 women collected after female kidney transplantation, several years after the initial blood testing. Women with ESRD showed statistically higher frequencies (62%) and quantities (98 genome equivalent cells per million of host cells, gEq/M) of male Mc in their PBMC than healthy women (16% and 0.3 gEq/M, ppregnancy and/or of blood transfusion. Three out of five renal biopsies obtained a few years prior to the blood test also contained Mc, but no correlation could be established between earlier Mc in a kidney and later presence in PBMC. Finally, several years after female kidney transplantation, male Mc was totally cleared from PBMC in all women tested but one. This intriguing and striking initial result of natural and iatrogenic male Mc persistence in peripheral blood from women with ESRD raises several hypotheses for the possible role of these cells in renal diseases. Further studies are needed to elucidate mechanisms of recruitment and persistence of Mc in women with ESRD.

  6. Phytoestrogens for menopausal bone loss and climacteric symptoms.

    Science.gov (United States)

    Lagari, Violet S; Levis, Silvina

    2014-01-01

    Women have always looked for non-hormonal options to alleviate menopausal vasomotor symptoms and prevent menopausal bone loss. The use of complementary and alternative medicine for these purposes has particularly increased after the publication of the Women's Health Initiative's results suggesting that there might be more risks than benefits with hormone replacement. Phytoestrogens are plant-derived estrogens that, although less potent than estradiol, bind to the estrogen receptor and can function as estrogen agonists or antagonists. Soy isoflavones extracted from soy are the phytoestrogens most commonly used by menopausal women. Because typical Western diets are low in phytoestrogens and taking into account the general difficulty in changing dietary habits, most clinical trials in Western women have used isoflavone-fortified foods or isoflavone tablets. Although some women might experience a reduction in the frequency or severity of hot flashes, most studies point towards the lack of effectiveness of isoflavones derived from soy or red clover, even in large doses, in the prevention of hot flashes and menopausal bone loss. This article is part of a Special Issue entitled 'Phytoestrogens'.

  7. Health behaviors of postmenopausal women

    Science.gov (United States)

    Żułtak-Bączkowska, Katarzyna; Mroczek, Bożena; Kotwas, Artur; Kemicer-Chmielewska, Ewa; Karakiewicz, Beata; Starczewski, Andrzej

    2014-01-01

    Introduction Health status and health-related quality of life of postmenopausal women are issues, which nowadays pose a serious challenge to many domains of science. Climacteric symptoms which occur at this stage of life, lower its quality and make a negative contribution to self-reported health status, are mostly observed in a particular group of women. Evaluation of health behaviors performed using a standardized questionnaire, the Health Behavior Inventory (HBI), may help establish a comprehensive diagnosis of women's health, and thus select effective interventions. A systemic approach to menopause assumes that full fitness of women and good quality of their lives can be maintained not only by means of pharmacotherapy but also other forms of action, especially health education oriented towards changes in the lifestyle and promotion of healthy behaviors. The aim of this study Aim of the study is to perform a HBI-based assessment of women's health behaviors in such categories as healthy eating habits (HEH), preventive behaviors (PB), positive mental attitudes (PMA), and health practices (HP). Material and methods The study involved 151 healthy postmenopausal women. A research tool was a standardized questionnaire, the Health Behavior Inventory (HBI). Results The surveyed women obtained 70% of the maximum score on average, which suggests a medium level of health behaviors in this group. The levels of health behaviors in the categories of positive mental attitudes and health practices significantly differed between older women and their younger counterparts (higher levels were observed among older respondents). There were also significant differences in the levels of healthy behaviors between women with secondary and higher education (those better educated declared healthy behaviors more often). There was no correlation between the level of health behaviors and the BMI of the surveyed women. Conclusions Older women attached greater importance to positive mental

  8. Influence on birthing positions affects women's sense of control in second stage of labour

    NARCIS (Netherlands)

    Nieuwenhuijze, M.J.; Jonge, A. de; Korstjens, I.; Bude, L.; Lagro-Janssen, T.

    2013-01-01

    OBJECTIVE: to explore whether choices in birthing positions contributes to women's sense of control during birth. DESIGN: survey using a self-report questionnaire. Multiple regression analyses were used to investigate which factors associated with choices in birthing positions affected women's sense

  9. The Pathogenesis of Climacteric Syndrome and Principle of Acupuncture Treatment Based on TCM Theory about Brain

    Institute of Scientific and Technical Information of China (English)

    Shen Xiaoming; Du Yuanhao; Shi Xuemin

    2005-01-01

    The brain is the sea of marrow, stores the cerebral spirit and dominates all the life activities of the human body, which are the basic TCM knowledge about the brain. Based on this knowledge, the pathogenesis of climacteric syndrome is considered as consumption and deficiency of kidney-essence, and incoordination between the brain and kidney. The principle of acupuncture treatment should be soothing the mind and tonifying the kidney.

  10. Analysis of gene expression during the transition to climacteric phase in carnation flowers (Dianthus caryophyllus L.).

    Science.gov (United States)

    In, Byung-Chun; Binder, Brad M; Falbel, Tanya G; Patterson, Sara E

    2013-11-01

    It has been generally thought that in ethylene-sensitive plants such as carnations, senescence proceeds irreversibly once the tissues have entered the climacteric phase. While pre-climacteric petal tissues have a lower sensitivity to ethylene, these tissues are converted to the climacteric phase at a critical point during flower development. In this study, it is demonstrated that the senescence process initiated by exogenous ethylene is reversible in carnation petals. Petals treated with ethylene for 12h showed sustained inrolling and senescence, while petals treated with ethylene for 10h showed inrolling followed by recovery from inrolling. Reverse transcription-PCR analysis revealed differential expression of genes involved in ethylene biosynthesis and ethylene signalling between 10h and 12h ethylene treatment. Ethylene treatment at or beyond 12h (threshold time) decreased the mRNA levels of the receptor genes (DcETR1, DcERS1, and DcERS2) and DcCTR genes, and increased the ethylene biosynthesis genes DcACS1 and DcACO1. In contrast, ethylene treatment under the threshold time caused a transient decrease in the receptor genes and DcCTR genes, and a transient increase in DcACS1 and DcACO1. Sustained DcACS1 accumulation is correlated with decreases in DcCTR genes and increase in DcEIL3 and indicates that tissues have entered the climacteric phase and that senescence proceeds irreversibly. Inhibition of ACS (1-aminocyclopropane-1-carboxylic acid synthase) prior to 12h ethylene exposure was not able to prevent reduction in transcripts of DcCTR genes, yet suppressed transcript of DcACS1 and DcACO1. This leads to the recovery from inrolling of the petals, indicating that DcACS1 may act as a signalling molecule in senescence of flowers.

  11. CLINICAL STUDY ON CLIMACTERIC SYNDROME TREATED WITH AURICULAR PLUS BODY ACUPUNCTURE

    Institute of Scientific and Technical Information of China (English)

    徐天舒

    2003-01-01

    Aim: To search for the best therapeutic method for climacteric syndrome. Methods: A total of 190 cases of climacteric syndrome participants were randomly divided into auricular plus body acupuncture group (treatment group, n = 96) and simple body acupuncture group (control group, n = 94). Serum sexual hormone (FSH, LH and E2) and blood lipid (TC, LDL-C, HDL-C and TG) levels were detected before and after treatment. Results: After 30sessions of treatment, the total effective rates of treatment and control groups were 82.29% and 76.02% respectively, with the former being significantly higher than the later ( P < 0.01 ). In comparison with pre-treatment of each group, serum follicle-stimulating hormone (FSH) and luterotropic hormone (LH) levels lowered significantly; serum estradiol (E2) increased remarkably ( P < 0.05 - 0.01 ); serum high-density l ipoprotein-cholesterol (HDL-C) of two groups raised significantly ( P< 0.05- 0.01 ), and Iow-density lipoprotein (LDL)-C of treatment group decreased evidently (P< 0.05). In addition, the improvement of complaints of hot flushes, sweating, paresthesia, insomnia and emotional irritability in treatment group is significantly better than that of control group. Conclusion: Auricular acupuncture combined with body acupuncture has a better therapeutic effect than that of simple body acupuncture in the treatment of climacteric syndrome.

  12. Health behaviors of postmenopausal women

    Directory of Open Access Journals (Sweden)

    Maria Jasińska

    2014-03-01

    Full Text Available Introduction: Health status and health-related quality of life of postmenopausal women are issues, which nowadays pose a serious challenge to many domains of science. Climacteric symptoms which occur at this stage of life, lower its quality and make a negative contribution to self-reported health status, are mostly observed in a particular group of women. Evaluation of health behaviors performed using a standardized questionnaire, the Health Behavior Inventory (HBI, may help establish a comprehensive diagnosis of women’s health, and thus select effective interventions. A systemic approach to menopause assumes that full fitness of women and good quality of their lives can be maintained not only by means of pharmacotherapy but also other forms of action, especially health education oriented towards changes in the lifestyle and promotion of healthy behaviors. The aim of this study is to perform a HBI-based assessment of women’s health behaviors in such categories as healthy eating habits (HEH, preventive behaviors (PB, positive mental attitudes (PMA, and health practices (HP. Material and methods: The study involved 151 healthy postmenopausal women. A research tool was a standardized questionnaire, the Health Behavior Inventory (HBI. Results: The surveyed women obtained 70% of the maximum score on average, which suggests a medium level of health behaviors in this group. The levels of health behaviors in the categories of positive mental attitudes and health practices significantly differed between older women and their younger counterparts (higher levels were observed among older respondents. There were also significant differences in the levels of healthy behaviors between women with secondary and higher education (those better educated declared healthy behaviors more often. There was no correlation between the level of health behaviors and the BMI of the surveyed women. Conclusions : Older women attached greater

  13. Genetic variants at 1p11.2 and breast cancer risk: a two-stage study in Chinese women.

    Directory of Open Access Journals (Sweden)

    Yue Jiang

    Full Text Available BACKGROUND: Genome-wide association studies (GWAS have identified several breast cancer susceptibility loci, and one genetic variant, rs11249433, at 1p11.2 was reported to be associated with breast cancer in European populations. To explore the genetic variants in this region associated with breast cancer in Chinese women, we conducted a two-stage fine-mapping study with a total of 1792 breast cancer cases and 1867 controls. METHODOLOGY/PRINCIPAL FINDINGS: Seven single nucleotide polymorphisms (SNPs including rs11249433 in a 277 kb region at 1p11.2 were selected and genotyping was performed by using TaqMan® OpenArray™ Genotyping System for stage 1 samples (878 cases and 900 controls. In stage 2 (914 cases and 967 controls, three SNPs (rs2580520, rs4844616 and rs11249433 were further selected and genotyped for validation. The results showed that one SNP (rs2580520 located at a predicted enhancer region of SRGAP2 was consistently associated with a significantly increased risk of breast cancer in a recessive genetic model [Odds Ratio (OR  =  1.66, 95% confidence interval (CI  =  1.16-2.36 for stage 2 samples; OR  =  1.51, 95% CI  =  1.16-1.97 for combined samples, respectively]. However, no significant association was observed between rs11249433 and breast cancer risk in this Chinese population (dominant genetic model in combined samples: OR  =  1.20, 95% CI  =  0.92-1.57. CONCLUSIONS/SIGNIFICANCE: Genotypes of rs2580520 at 1p11.2 suggest that Chinese women may have different breast cancer susceptibility loci, which may contribute to the development of breast cancer in this population.

  14. Staging of women with breast cancer after introduction of sentinel node guided axillary dissection

    DEFF Research Database (Denmark)

    Tvedskov, Tove Filtenborg

    2012-01-01

    Today, sentinel lymph node dissection (SLND) has replaced axillary lymph node dissection (ALND) as standard procedure for staging of the axilla in the treatment of breast cancer. SLND can accurately stage the axilla by removing on average only two lymph nodes. Only in case of metastatic spread...... to sentinel nodes an ALND is offered. Removing fewer nodes has made more extensive histopathological examinations of the lymph nodes possible and as a consequence more metastases are found. This has resulted in stage migration. Based on data from the nationwide Danish Breast Cancer Cooperative Group (DBCG.......8%, when estimated using today´s criteria for risk-allocation, because nodal status is now less important in risk-allocation. In general, only 15-20% of patients with micrometastases and 10-15% of patients with isolated tumor cells (ITC) in sentinel node have further metastatic spread to non-sentinel nodes...

  15. Stages of change of behavior in women on a multi-professional program for treatment of obesity 1

    Science.gov (United States)

    Bevilaqua, Cheila Aparecida; Pelloso, Sandra Marisa; Marcon, Sonia Silva

    2016-01-01

    ABSTRACT Objective: to ascertain the effectiveness of an intervention program in relation to anthropometric measurements and stage of readiness for behavioral change in women with excess weight. Methods: the intervention group (IG) was made up of 13 women, and the control group (CG), by 20. The intervention lasted 16 weeks, and included the practice of guided physical activity three times a week, and health education once a week. The application of the questionnaire on stage of readiness for behavioral change, and the anthropometric evaluations, were undertaken at two points - before and after the period of intervention. The statistical analysis involved tests of comparison and association. Results: in general, at the first point, the participants in the two groups were predisposed to make changes in what they ate and in their physical activity. However, significant difference was only observed in relation to weight, body mass index (BMI), waist circumference and waist-hip ratio and readiness for change among the members of the intervention group. Conclusion: the intervention programmed was effective in weight loss, reduction of waist circumference and waist-hip ratio, and in changing behaviors related to the practicing of physical exercise and eating habits. PMID:27737377

  16. Stages of change of behavior in women on a multi-professional program for treatment of obesity

    Directory of Open Access Journals (Sweden)

    Cheila Aparecida Bevilaqua

    Full Text Available ABSTRACT Objective: to ascertain the effectiveness of an intervention program in relation to anthropometric measurements and stage of readiness for behavioral change in women with excess weight. Methods: the intervention group (IG was made up of 13 women, and the control group (CG, by 20. The intervention lasted 16 weeks, and included the practice of guided physical activity three times a week, and health education once a week. The application of the questionnaire on stage of readiness for behavioral change, and the anthropometric evaluations, were undertaken at two points - before and after the period of intervention. The statistical analysis involved tests of comparison and association. Results: in general, at the first point, the participants in the two groups were predisposed to make changes in what they ate and in their physical activity. However, significant difference was only observed in relation to weight, body mass index (BMI, waist circumference and waist-hip ratio and readiness for change among the members of the intervention group. Conclusion: the intervention programmed was effective in weight loss, reduction of waist circumference and waist-hip ratio, and in changing behaviors related to the practicing of physical exercise and eating habits.

  17. Socioeconomic position and stage of cervical cancer in Danish women diagnosed 2005 to 2009

    DEFF Research Database (Denmark)

    Ibfelt, Else; Kjær, Susanne Krüger; Johansen, Christoffer

    2012-01-01

    To reduce social disparities in cervical cancer survival, it is important to understand the mechanisms by which social position influence cancer prognosis. We investigated the relations between socioeconomic factors, comorbidity, time since last Papanicolau smear, and stage at diagnosis in Danish...

  18. [Benefits of moderate beer consumption at different stages of life of women].

    Science.gov (United States)

    Pérez Medina, Tirso; de Argila Fernández-Durán, Nuria; Pereira Sánchez, Augusto; Serrano González, Lucía

    2015-07-18

    Beer is a natural beverage low calorie, low degree of alcohol, no fats or sugars and a significant amount of carbohydrates, vitamins, and proteins. Beneficial health qualities are based on the presence in the beer of antioxidant compounds (polyphenols), which reduce the presence of free radicals in the organism, and phytoestrogens, elements biosimilars to natural estrogens. In pregnant women, beer, obviously alcohol-free, presents elements in its composition that differ it from other fermented beverages as it is the folic acid, vitamin necessary to prevent defects of the neural tube in the fetus or regulate homocysteine. With regard to breastfeeding, beer alcohol-free supplementation increases the antioxidant activity in breast milk and therefore reduces the oxidative stress of the newborn after birth In menopause, the presence of antioxidants, vitamins, nutrients, and dietetic fiber, as well as phytoestrogens, is highly beneficial in the prevention of pathologies arising from the decline in estrogens. Osteoporosis also is effectively combated by the beer. The intake of beer, favors a greater bone mass in women, irrespective of their gonadal status.

  19. Tomato ACS4 is necessary for timely start of and progression through the climacteric phase of fruit ripening

    Science.gov (United States)

    Hoogstrate, Suzanne W.; van Bussel, Lambertus J. A.; Cristescu, Simona M.; Cator, Eric; Mariani, Celestina; Vriezen, Wim H.; Rieu, Ivo

    2014-01-01

    Climacteric fruit ripening, as it occurs in many fruit crops, depends on a rapid, autocatalytic increase in ethylene production. This agriculturally important process has been studied extensively, with tomato simultaneously acting both as a model species and target crop for modification. In tomato, the ethylene biosynthetic genes ACC SYNTHASE2 (ACS2) and ACS4 are highly expressed during fruit ripening, with a combined loss of both ACS2 and ACS4 activity preventing generation of the ethylene burst necessary for fruit ripening. However, the individual roles and importance of ACS2 and ACS4 have not been determined. In this study, we examined specifically the role of ACS4 by comparing the phenotype of an acs4 mutant firstly with that of the wild-type, and secondly with two novel ripening-inhibitor (rin) mutants. Ethylene production during ripening was significantly reduced in both acs4-1, and rin lines, with rin genotypes showing the weaker ethylene burst. Also i) the time between anthesis and the start of fruit ripening and ii) the time required to progress through ripening were significantly longer in acs4-1 than in the wild type, but shorter than in the strongest rin mutant. The delay in ripening was reflected in the lower expression of ripening-related transcripts during the mature green and light red ripening stages. Furthermore, expression of ACS2 and ACS4 was strongly dependent on a functional RIN gene, while ACS2 expression was largely independent of ACS4. Altogether, we show that ACS4 is necessary for normal progression of tomato fruit ripening and that mutation of this gene may provide a useful means for altering ripening traits. PMID:25278945

  20. Tomato ACS4 is necessary for timely start of and progression through the climacteric phase of fruit ripening

    Directory of Open Access Journals (Sweden)

    Suzanne eHoogstrate

    2014-09-01

    Full Text Available Climacteric fruit ripening, as it occurs in many fruit crops, depends on a rapid, autocatalytic increase in ethylene production. This agriculturally important process has been studied extensively, with tomato simultaneously acting both as a model species and target crop for modification. In tomato, the ethylene biosynthetic genes ACC SYNTHASE2 (ACS2 and ACS4 are highly expressed during fruit ripening, with a combined loss of both ACS2 and ACS4 activity preventing generation of the ethylene burst necessary for fruit ripening. However, the individual roles and importance of ACS2 and ACS4 have not been determined. In this study, we examined specifically the role of ACS4 by comparing the phenotype of an acs4 mutant firstly with that of the wild-type, and secondly with two novel ripening-inhibitor (rin mutants. Ethylene production during ripening was significantly reduced in both acs4-1, and rin lines, with rin genotypes showing the weaker ethylene burst. Also i the time between anthesis and the start of fruit ripening and ii the time required to progress through ripening were significantly longer in acs4-1 than in the wild type, but shorter than in the strongest rin mutant. The delay in ripening was reflected in the lower expression of ripening-related transcripts during the mature green and light red ripening stages. Furthermore, expression of ACS2 and ACS4 was strongly dependent on a functional RIN gene, while ACS2 expression was largely independent of ACS4. Altogether, we show that ACS4 is necessary for normal progression of tomato fruit ripening and that mutation of this gene may provide a useful means for altering ripening traits.

  1. HEALTH EDUCATION AS A TOOL FOR WOMEN IN CLIMACTERIC: GRANTS FOR NURSING CARE

    Directory of Open Access Journals (Sweden)

    Jéssica de Lyra Sousa

    2012-01-01

    Full Text Available Objetivo:. Conhecer a assistência prestada pelo enfermeiro à mulher no climatério identificando estratégias de educação em saúde no atendimento à mesma. Metodologia:. Realizado levantamento de dados sobre o tema entre 2001 a 2010 seguindo leitura analítica alcançando bibliografia potencial com 10 artigos e 1 monografia divididos em três categorias. Resultados e discussão:. Algumas obras demonstram que as mulheres desconhecem a educação pela enfermagem, constatado pela falta de informações dessas pacientes. Conclusão:. O enfermeiro como educador se insere como grande estímulo, beneficiando estas mulheres com informações, com variados métodos desempenhados buscando vivenciar estas alterações fisiológicas de forma mais saudável permitindo a transformação consciente da realidade. Educar em saúde tornou-se uma das atribuições que o enfermeiro desempenha em toda sua área de atuação e, portanto perpassa todos os níveis de assistência à saúde.

  2. Malate Oxidation and Cyanide-Insensitive Respiration in Avocado Mitochondria during the Climacteric Cycle.

    Science.gov (United States)

    Moreau, F; Romani, R

    1982-11-01

    After preparation on self-generated Percoll gradients, avocado (Persea americana Mill, var. Fuerte and Hass) mitochondria retain a high proportion of cyanide-insensitive respiration, especially with alpha-ketoglutarate and malate as substrates. Whereas alpha-ketoglutarate oxidation remains unchanged, the rate of malate oxidation increases as ripening advances through the climacteric. An enhancement of mitochondrial malic enzyme activity, measured by the accumulation of pyruvate, closely parallels the increase of malate oxidation. The capacity for cyanide-insensitive respiration is also considerably enhanced while respiratory control decreases (from 3.3 to 1.7), leading to high state 4 rates.Both malate dehydrogenase and malic enzyme are functional in state 3, but malic enzyme appears to predominate before the addition of ADP and after its depletion. In the presence of cyanide, a membrane potential is generated when the alterntive pathway is operating. Cyanide-insensitive malate oxidation can be either coupled to the first phosphorylation site, sensitive to rotenone, or by-pass this site. In the absence of phosphate acceptor, malate oxidation is mainly carried out via malic enzyme and the alternative pathway. Experimental modification of the external mitochondrial environment in vitro (pH, NAD(+), glutamade) results in changes in malate dehydrogenase and malic enzyme activities, which also modify cyanide resistance. It appears that a functional connection exists between malic enzyme and the alternative pathway via a rotenone-insensitive NADH dehydrogenase and that this pathway is responsible, in part, for nonphosphorylating respiratory activity during the climacteric.

  3. Can Locoregional Treatment of the Primary Tumor Improve Outcomes for Women With Stage IV Breast Cancer at Diagnosis?

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, David H.A., E-mail: dhanguyen@yahoo.com [British Columbia Cancer Agency, Department of Radiation Oncology, BC (Canada); Departement de Radio-Oncologie, Hopital Maisonneuve-Rosemont, Montreal, Quebec (Canada); Truong, Pauline T. [British Columbia Cancer Agency, Department of Radiation Oncology, BC (Canada); Breast Cancer Outcomes Unit, British Columbia Cancer Agency, BC (Canada); University of British Columbia, BC (Canada); Alexander, Cheryl; Walter, Caroline V.; Hayashi, Emily; Christie, Jennifer [Breast Cancer Outcomes Unit, British Columbia Cancer Agency, BC (Canada); Lesperance, Mary [Department of Mathematics and Statistics, University of Victoria, BC (Canada)

    2012-09-01

    Purpose: To examine the effect of locoregional treatment (LRT) of the primary tumor on survival in patients with Stage IV breast cancer at diagnosis. Methods and Materials: The study cohort comprised 733 women referred to the British Columbia Cancer Agency between 1996 and 2005 with newly diagnosed clinical or pathologic M1 breast cancer. Tumor and treatment characteristics, overall survival (OS), and locoregional progression-free survival were compared between patients treated with (n = 378) and without (n = 355) LRT of the primary disease. Multivariable analysis was performed with Cox regression modeling. Results: The median follow-up time was 1.9 years. LRT consisted of surgery alone in 67% of patients, radiotherapy alone in 22%, and both in 11%. LRT was used more commonly in women with age <50 years, Eastern Cooperative Oncology Group (ECOG) performance status 0-1, Stage T1-2 tumors, N0-1 disease, limited M1 burden, and asymptomatic M1 disease (all p < 0.05). Systemic therapy was used in 92% of patients who underwent LRT and 85% of patients who did not. In patients treated with LRT compared with those without LRT, the 5-year OS rates were 21% vs. 14% (p < 0.001), and the rates of locoregional progression-free survival were 72% vs. 46% (p < 0.001). Among 378 patients treated with LRT, the rates of 5-year OS were higher in patients with age <50, ECOG performance status 0-1, estrogen receptor-positive disease, clear surgical margins, single subsite, bone-only metastasis, and one to four metastatic lesions (all p < 0.003). On multivariable analysis, LRT was associated with improved OS (hazard ratio, 0.78; 95% confidence interval, 0.64-0.94, p = 0.009). Conclusion: Locoregional treatment of the primary disease is associated with improved survival in some women with Stage IV breast cancer at diagnosis. Among those treated with LRT, the most favorable rates of survival were observed in subsets with young age, good performance status, estrogen receptor-positive disease

  4. Current Status of Female Climacteric Syndrome and Its Influencing Factors%女性更年期综合征现状及影响因素分析

    Institute of Scientific and Technical Information of China (English)

    王晓凡; 张海芹

    2014-01-01

    目的:调查女性更年期综合征的现状,探讨其影响因素。方法采用一般情况调查表、改良更年期 Kupermann评分量表和症状自评量表、艾森克个性问卷,对833例更年期女性进行调查,采用字2检验、皮尔逊相关性分析与多元回归分析进行统计处理。结果本组女性更年期综合征发生率为77.6%,城市、已婚、补充豆浆/牛奶女性组群更年期症状评分显著性低于来自农村、没有补充豆浆/牛奶的女性组群(P<0.01);更年期症状评分与自评症状量表总分、神经质维度得分呈正相关(相关系数为0.432、0.344,P<0.01),与内外向维度得分呈显负相关(相关系数为-0.155,P<0.01);经多元线性回归分析,自评症状量表总分、神经质维度得分、内外向维度得分进入回归方程(回归系数分别是0.752、0.302、-0.149,P<0.01或P<0.05)。结论女性更年期症状与城乡、年龄、长期补充豆浆、心理症状及人格特质有关。%Objective To inquire the present situation of female climacteric syndrome and investigate its influencing factors. Methods With Kupermann menopause rating scale and SCL-90 symptom checklist and EPQ, Totally 833 menopausal women were investigated in the survey. Results The incidence of female climacteric syndrome reached up to77.6%; The Kupermann menopause rating scale score of urban married women with additional soya-bean milk or milk was significantly lower than that of rural women without any addition of soya-bean milk or milk (P<0.01). Kupermann menopause rating scale score, SCL-90 total score and N (neuroticism)of EPQ score were significantly positive correlated;Kupermann menopause rating scale score and E(extraversion) of EPQ score were significantly negative correlated; By multiple linear regression analysis, SCL-90 total score, the neurotic score, N (neuroticism) and E (extraversion) of EPQ score entered regression equation

  5. Dose-Dependent Effects of the Cimicifuga racemosa Extract Ze 450 in the Treatment of Climacteric Complaints: A Randomized, Placebo-Controlled Study

    Directory of Open Access Journals (Sweden)

    Ruediger Schellenberg

    2012-01-01

    Full Text Available Extracts from Cimicifuga racemosa (CR, synonym Actaea racemosa have shown efficacy in trials in women with menopausal symptoms. Yet, dose dependency remains unclear. Therefore, 180 female outpatients with climacteric complaints were treated for 12 weeks in a randomized, double-blind, placebo-controlled, 3-armed trial (CR extract Ze 450 in 6.5 mg or 13.0 mg, or placebo. Primary outcome was the difference in menopausal symptoms (vasomotor, psychological, and somatic, assessed by the Kupperman Menopausal Index between baseline and week 12. Secondary efficacy variables were patients’ self-assessments of general quality of life (QoL, responder rates, and safety. Compared to placebo, patients receiving Ze 450 showed a significant reduction in the severity of menopausal symptoms in a dose-dependent manner from baseline to endpoint (mean absolute differences 17.0 (95% CI 14.65–19.35 score points, P<0.0001 for 13.0 mg; mean absolute differences 8.47 (95% CI 5.55–11.39 score points, P=0.0003 for 6.5 mg. QoL and responder rates corresponded with the main endpoint. Changes in menopausal symptoms and QoL were inversely correlated. Reported adverse events and clinical laboratory testing did not raise safety concerns. The CR extract Ze 450 is an effective and well-tolerated nonhormonal alternative to hormone treatment for symptom relief in menopausal women.

  6. A SEPALLATA gene is involved in the development and ripening of strawberry (Fragaria x ananassa Duch.) fruit, a non-climacteric tissue.

    Science.gov (United States)

    Seymour, Graham B; Ryder, Carol D; Cevik, Volkan; Hammond, John P; Popovich, Alexandra; King, Graham J; Vrebalov, Julia; Giovannoni, James J; Manning, Kenneth

    2011-01-01

    Climacteric and non-climacteric fruits have traditionally been viewed as representing two distinct programmes of ripening associated with differential respiration and ethylene hormone effects. In climacteric fruits, such as tomato and banana, the ripening process is marked by increased respiration and is induced and co-ordinated by ethylene, while in non-climacteric fruits, such as strawberry and grape, it is controlled by an ethylene-independent process with little change in respiration rate. The two contrasting mechanisms, however, both lead to texture, colour, and flavour changes that probably reflect some common programmes of regulatory control. It has been shown that a SEPALLATA(SEP)4-like gene is necessary for normal ripening in tomato. It has been demonstrated here that silencing a fruit-related SEP1/2-like (FaMADS9) gene in strawberry leads to the inhibition of normal development and ripening in the petal, achene, and receptacle tissues. In addition, analysis of transcriptome profiles reveals pleiotropic effects of FaMADS9 on fruit development and ripening-related gene expression. It is concluded that SEP genes play a central role in the developmental regulation of ripening in both climacteric and non-climacteric fruits. These findings provide important information to extend the molecular control of ripening in a non-climacteric fruit beyond the limited genetic and cultural options currently available.

  7. The value of complementary and alternative medicine in the treatment of climacteric symptoms : Results of a survey among German gynecologists

    NARCIS (Netherlands)

    von Studnitz, Friederike S. G.; Eulenburg, Christine; Mueck, Alfred O.; Buhling, Kai J.

    2013-01-01

    Objectives: The present study aims to detect the attitude and experience towards complementary and alternative medicine (CAM) in the treatment of climacteric disorders among gynecologists in Germany. Study design: A self-administered questionnaire, containing 15 questions, was sent to all gynecologi

  8. Type 2 diabetes mellitus and prognosis in early stage breast cancer women.

    Science.gov (United States)

    Kaplan, Muhammet Ali; Pekkolay, Zafer; Kucukoner, Mehmet; Inal, Ali; Urakci, Zuhat; Ertugrul, Hamza; Akdogan, Recai; Firat, Ugur; Yildiz, Ismail; Isikdogan, Abdurrahman

    2012-09-01

    It has been suggested that type 2 diabetes mellitus may affect breast cancer prognosis, possibly due to increased diabetes-related comorbidity, or direct effects of insulin resistance and/or hyperinsulinemia. The aim of this study was to determine the impact of diabetes on disease-free survival (DFS) following mastectomy for breast cancer patients. The cases included in this retrospective study were selected from breast cancer women who had undergone mastectomy and completed adjuvant chemotherapy from 1998 to 2010. Patients were classified into two groups: diabetic and non-diabetic. Patients' age, sex, menopausal status, body mass index (BMI), histopathological features, tumor size, lymph node involvement, hormone receptor and HER2-neu status, and treatment types were recorded. There were 483 breast cancer patients included in the study. Postmenopausal patients' rate (53.7% vs. 36.8%, P = 0.016) and mean BMI levels were statistically higher (32.2 vs. 27.9, P = 0.007) in diabetic patients. There was no statistical difference for histological subgroup, grade, ER and PR positivity, HER2-neu overexpression rate, and tumor size between the diabetic and non-diabetic group. Lymph node involvements were statistically higher in diabetic patients compared with non-diabetic patients (P = 0.013). Median disease-free survival is 81 months (95% CI, 61.6-100.4) in non-diabetic patients and 36 months (95% CI, 13.6-58.4) in diabetic patients (P breast cancer.

  9. Similar Survival With Breast Conservation Therapy or Mastectomy in the Management of Young Women With Early-Stage Breast Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Mahmood, Usama, E-mail: usama.mahmood@gmail.com [Department of Radiation Oncology, University of Maryland, Baltimore, Maryland (United States); Morris, Christopher; Neuner, Geoffrey [Department of Radiation Oncology, University of Maryland, Baltimore, Maryland (United States); Koshy, Matthew [Department of Cellular and Radiation Oncology, University of Chicago, Chicago, Illinois (United States); Kesmodel, Susan; Buras, Robert [Department of Surgery, University of Maryland, Baltimore, Maryland (United States); Chumsri, Saranya; Bao Ting; Tkaczuk, Katherine [Department of Medicine, University of Maryland, Baltimore, Maryland (United States); Feigenberg, Steven [Department of Radiation Oncology, University of Maryland, Baltimore, Maryland (United States)

    2012-08-01

    Purpose: To evaluate survival outcomes of young women with early-stage breast cancer treated with breast conservation therapy (BCT) or mastectomy, using a large, population-based database. Methods and Materials: Using the Surveillance, Epidemiology, and End Results (SEER) database, information was obtained for all female patients, ages 20 to 39 years old, diagnosed with T1-2 N0-1 M0 breast cancer between 1990 and 2007, who underwent either BCT (lumpectomy and radiation treatment) or mastectomy. Multivariable and matched pair analyses were performed to compare overall survival (OS) and cause-specific survival (CSS) of patients undergoing BCT and mastectomy. Results: A total of 14,764 women were identified, of whom 45% received BCT and 55% received mastectomy. Median follow-up was 5.7 years (range, 0.5-17.9 years). After we accounted for all patient and tumor characteristics, multivariable analysis found that BCT resulted in OS (hazard ratio [HR], 0.93; 95% confidence interval [CI], 0.83-1.04; p = 0.16) and CSS (HR, 0.93; CI, 0.83-1.05; p = 0.26) similar to that of mastectomy. Matched pair analysis, including 4,644 BCT and mastectomy patients, confirmed no difference in OS or CSS: the 5-, 10-, and15-year OS rates for BCT and mastectomy were 92.5%, 83.5%, and 77.0% and 91.9%, 83.6%, and 79.1%, respectively (p = 0.99), and the 5-, 10-, and 15-year CSS rates for BCT and mastectomy were 93.3%, 85.5%, and 79.9% and 92.5%, 85.5%, and 81.9%, respectively (p = 0.88). Conclusions: Our analysis of this population-based database suggests that young women with early-stage breast cancer have similar survival rates whether treated with BCT or mastectomy. These patients should be counseled appropriately regarding their treatment options and should not choose a mastectomy based on the assumption of improved survival.

  10. Development of Patients' Decision Aid for Older Women With Stage I Breast Cancer Considering Radiotherapy After Lumpectomy

    Energy Technology Data Exchange (ETDEWEB)

    Wong, Jennifer [Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario (Canada); D' Alimonte, Laura [Department of Radiation Therapy, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario (Canada); Angus, Jan [Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario (Canada); Paszat, Larry [Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario (Canada); Metcalfe, Kelly [Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario (Canada); Whelan, Tim [Department of Radiation Oncology, Juravinski Cancer Centre, McMaster University, Hamilton, Ontario (Canada); Llewellyn-Thomas, Hilary [Department of Community and Family Medicine, The Center of Informed Choice, The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Medical School, Lebanon, NH (Lebanon); Warner, Eiran [Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario (Canada); Franssen, Edmee [Consultant Statistician, Faculty of Medicine, University of Toronto, Toronto, Ontario (Canada); Szumacher, Ewa, E-mail: Ewa.Szumacher@sunnybrook.ca [Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario (Canada)

    2012-09-01

    Purpose: To develop a patient decision aid (PtDA) for older women with Stage I, pathologically node negative, estrogen receptor-positive progesterone receptor-positive breast cancer who are considering adjuvant radiotherapy after lumpectomy and to examine its impact on patients' decision making. Methods and Materials: A PtDA was developed and evaluated in three steps according to the Ottawa Decision Support Framework: (1) needs assessment (n = 16); (2) Pilot I to examine PtDA acceptability (n = 12); and (3) Pilot II, a pretest posttest (n = 38) with older women with estrogen receptor-positive progesterone receptor-positive breast cancer after lumpectomy who were receiving adjuvant radiation therapy. Measures included patients' satisfaction with the PtDA, self-reported decisional conflict, level of distress, treatment-related knowledge, and choice predisposition. Results: The PtDA is a booklet that details each adjuvant treatment option's benefits, risks, and side effects tailored to the patient's clinical profile; includes a values clarification exercise; and includes steps to guide patients towards their decision. On the basis of qualitative comments and satisfaction ratings, all women thought that the PtDA was helpful and informative. In comparison with their baseline scores, patients had a statistically significant (p < 0.05) reduction in decisional conflict (adjusted mean difference [AMD], -7.18; 95% confidence interval [CI], -13.50 to 12.59); increased clarity of the benefits and risks (AMD, -10.86; CI, -20.33 to 21.49); and improved general treatment knowledge (AMD, 8.99; CI, 2.88-10.28) after using the PtDA. General trends were also reported in the patients' choice predisposition scores that suggested potential differences in treatment decision after PtDA use. Conclusions: This study provides evidence that this PtDA may be a helpful educational tool for this group of women. The quality of care for older breast cancer patients may be

  11. Patient-Reported Outcomes and Early Discontinuation in Aromatase Inhibitor-Treated Postmenopausal Women With Early Stage Breast Cancer

    Science.gov (United States)

    Kadakia, Kunal C.; Snyder, Claire F.; Kidwell, Kelley M.; Seewald, Nicholas J.; Flockhart, David A.; Skaar, Todd C.; Desta, Zereunesay; Rae, James M.; Otte, Julie L.; Carpenter, Janet S.; Storniolo, Anna M.; Hayes, Daniel F.; Stearns, Vered

    2016-01-01

    Background. Early discontinuation of aromatase inhibitors (AIs) is common and leads to poor outcomes but is challenging to predict. In the Exemestane and Letrozole Pharmacogenetics trial, a high rate of early discontinuation due to intolerance was observed. We hypothesized that early changes in patient-reported outcomes (PROs) predict AI discontinuation and that biochemical factors are associated with changes in PROs. Patients and Methods. Postmenopausal women with early-stage breast cancer enrolled in a prospective randomized trial of exemestane versus letrozole completed questionnaires at baseline and serially over 24 months to assess overall quality of life (EuroQOL Visual Analog Scale [VAS]); mood; and multiple symptoms, including a musculoskeletal symptom cluster. A joint mixed-effects/survival model was used to estimate the effect of the change in PROs on AI discontinuation. Associations between biochemical factors and change in PROs were examined. Results. A total of 490 patients were analyzed. Worsening of EuroQOL VAS and the musculoskeletal cluster were associated with the highest risk for early discontinuation (hazard ratio [HR], 2.77 [95% confidence interval (CI), 2.72–2.81; p = .015]; HR, 4.39 [95% CI, 2.40–8.02; p < .0001], respectively). Pharmacokinetics and estrogen metabolism were not consistently associated with change in PRO measures. No clinically significant differences in any PRO between AIs were observed. Conclusion. Changes in PROs early during AI therapy were associated with treatment discontinuation. Identification of these changes could be used to target interventions in patients at high risk for early discontinuation. Implications for Practice: Early changes in patient-reported outcomes (PROs) can predict nonpersistence to aromatase inhibitor therapy. If used in clinical practice, PROs might identify women at highest risk for early discontinuation and allow for interventions to improve tolerance before significant toxicities develop

  12. Local Recurrence in Women With Stage I Breast Cancer: Declining Rates Over Time in a Large, Population-Based Cohort

    Energy Technology Data Exchange (ETDEWEB)

    Canavan, Joycelin, E-mail: canavanjoycelin@gmail.com [Radiation Therapy Program and Breast Cancer Outcomes Unit, British Columbia Cancer Agency, Vancouver Island Centre, University of British Columbia, Victoria, British Columbia (Canada); Truong, Pauline T.; Smith, Sally L. [Radiation Therapy Program and Breast Cancer Outcomes Unit, British Columbia Cancer Agency, Vancouver Island Centre, University of British Columbia, Victoria, British Columbia (Canada); Lu, Linghong; Lesperance, Mary [Department of Mathematics and Statistics, University of Victoria, British Columbia (Canada); Olivotto, Ivo A. [Department of Radiation Oncology, Tom Baker Cancer Centre, University of Calgary (Canada)

    2014-01-01

    Purpose: To evaluate whether local recurrence (LR) risk has changed over time among women with stage I breast cancer treated with breast-conserving therapy. Methods and Materials: Subjects were 5974 women aged ≥50 years diagnosis with pT1N0 breast cancer from 1989 to 2006, treated with breast-conserving surgery and radiation therapy. Clinicopathologic characteristics, treatment, and LR outcomes were compared among 4 cohorts stratified by year of diagnosis: 1989 to 1993 (n=1077), 1994 to 1998 (n=1633), 1999 to 2002 (n=1622), and 2003 to 2006 (n=1642). Multivariable analysis was performed, with year of diagnosis as a continuous variable. Results: Median follow-up time was 8.6 years. Among patients diagnosed in 1989 to 1993, 1994 to 1998, 1999 to 2002, and 2003 to 2006, the proportions of grade 1 tumors increased (16% vs 29% vs 40% vs 39%, respectively, P<.001). Surgical margin clearance rates increased from 82% to 93% to 95% and 88%, respectively (P<.001). Over time, the proportions of unknown estrogen receptor (ER) status decreased (29% vs 10% vs 1.2% vs 0.5%, respectively, P<.001), whereas ER-positive tumors increased (56% vs 77% vs 86% vs 86%, respectively, P<.001). Hormone therapy use increased (23% vs 23% vs 62% vs 73%, respectively, P<.001), and chemotherapy use increased (2% vs 5% vs 10% vs 13%, respectively, P<.001). The 5-year cumulative incidence rates of LR over the 4 time periods were 2.8% vs 1.7% vs 0.9% vs 0.8%, respectively (Gray's test, P<.001). On competing risk multivariable analysis, year of diagnosis was significantly associated with decreased LR (hazard ratio, 0.92 per year, P=.0003). Relative to grade 1 histology, grades 2, 3, and unknown were associated with increased LR. Hormone therapy use was associated with reduced LR. Conclusion: Significant changes in the multimodality management of stage I breast cancer have occurred over the past 2 decades. More favorable-risk tumors were diagnosed, and margin clearance and systemic therapy use

  13. 腹针治疗更年期综合征40例%Abdominal acupuncture for 40 cases of climacteric syndrome

    Institute of Scientific and Technical Information of China (English)

    顾群; 朱文罡

    2011-01-01

    Climacteric syndrome,so-called symptoms before and after menopause in TCM,encompasses a series of symptoms due to disorder of endocrine and autonomic nerve caused by declination of ovary function during perimenopausal period.In western medicine,the major treatment is hormone replacement therapy.However,different opinions exist on estrogen application and its safety,which shows more contraindications and adverse reactions combined.From 2004,the author has applied abdominal acupuncture on 40 cases of climacteric syndrome.

  14. Staging the axilla in women with breast cancer:the utility of preoperative ultrasound-guided needle biopsy

    Institute of Scientific and Technical Information of China (English)

    Nehmat Houssami; Robin M.Turner

    2014-01-01

    Preoperative staging of the axilla in women with invasive breast cancer using ultrasound-guided needle biopsy (UNB) identiifes approximately 50% of patients with axillary nodal metastases prior to surgical intervention. Although moderately sensitive, it is a highly speciifc staging strategy that is rarely falsely-positive, hence a positive UNB allows patients to be triaged to axillary lymph-node dissection (ALND) avoiding potentially unnecessary sentinel node biopsy (SNB). In this review, we extend our previous work through an updated literature search, focusing on studies that report data on UNB utility. Based on data for 10,934 breast cancer patients, sourced from 35 studies, a positive UNB allowed triage of 1,745 cases (simple proportion 16%) to axillary surgical treatment: the utility of UNB was a median 19.8% [interquartile range (IQR) 11.6%-26.7%] across these studies. We also modelled data from a subgroup of studies, and estimated that amongst patients with metastases to axillary nodes, the odds ratio (OR) for high nodal disease burden for a positive UNB versus a negative UNB was 4.38 [95% confidence interval (95% CI): 3.13, 6.13],P<0.001. From this model, the estimated proportion with high nodal disease burden was 58.9% (95% CI: 50.2%, 67.0%) for a positive UNB, whereas the estimated proportion with high nodal disease burden was 24.6% (95% CI: 17.7%, 33.2%) if UNB was negative. Overall, axillary UNB has good clinical utility and a positive UNB can effectively triage to ALND. However, the evolving landscape of axillary surgical treatment means that UNB will have relatively less utility where surgeons have modiifed their practice to omission of ALND for minimal nodal metastatic disease.

  15. Surgery Should Complement Endocrine Therapy for Elderly Postmenopausal Women with Hormone Receptor-Positive Early-Stage Breast Cancer

    Directory of Open Access Journals (Sweden)

    Olivier Nguyen

    2012-01-01

    Full Text Available Introduction. Endocrine therapy (ET is an integral part of breast cancer (BC treatment with surgical resection remaining the cornerstone of curative treatment. The objective of this study is to compare the survival of elderly postmenopausal women with hormone receptor-positive early-stage BC treated with ET alone, without radiation or chemotherapy, versus ET plus surgery. Materials and Methods. This is a retrospective study based on a prospective database. The medical records of postmenopausal BC patients referred to the surgical oncology service of two hospitals during an 8-year period were reviewed. All patients were to receive ET for a minimum of four months before undergoing any surgery. Results. Fifty-one patients were included and divided in two groups, ET alone and ET plus surgery. At last follow-up in exclusive ET patients (n=28, 39% had stable disease or complete response, 22% had progressive disease, of which 18% died of breast cancer, and 39% died of other causes. In surgical patients (n=23, 78% were disease-free, 9% died of recurrent breast cancer, and 13% died of other causes. Conclusions. These results suggest that surgical resection is beneficial in this group and should be considered, even for patients previously deemed ineligible for surgery.

  16. Alterations in Circulating miRNA Levels following Early-Stage Estrogen Receptor-Positive Breast Cancer Resection in Post-Menopausal Women

    DEFF Research Database (Denmark)

    Kodahl, Annette R; Zeuthen, Pernille; Binder, Harald

    2014-01-01

    design and the same qPCR profiling platform, resulting in limited agreement. CONCLUSIONS: A panel of 4 circulating miRNAs exhibited significantly altered levels following radical resection of primary ER+ breast cancers in post-menopausal women. These specific miRNAs may be involved in tumorigenesis...... these alterations were also observed in an independent data set. METHODS: Global miRNA analysis was performed on prospectively collected serum samples from 24 post-menopausal women with estrogen receptor-positive early-stage breast cancer before surgery and 3 weeks after tumor resection using global LNA...

  17. Síndrome do climatério: inquérito populacional domiciliar em Campinas, SP Climacteric syndrome: a population-based study in Brazil

    Directory of Open Access Journals (Sweden)

    Adriana Orcesi Pedro

    2003-12-01

    prevalence of climacteric, urogenital and sexual symptoms in a population of Brazilian women. METHODS: A cross-sectional descriptive population-based study was conducted. The selection of 456 women aged 45-60 years, living in Campinas, SP, in 1997, was done through area cluster sampling, according to data from the Brazilian Institute of Geography and Statistics. Data were collected via home interviews, using structured pretested questionnaires. Data were analyzed using the chi-squared test and the nonparametric Kruskal-Wallis test; a probability of <0.05 was considered statistically significant. The degree of climacteric symptoms was analyzed through circulatory and psychological indices. Analysis of the main components was used to determine symptom interrelationships. RESULTS: The most prevalent symptoms were nervousness (82%, hot flushes (70%, headache (68%, irritability (67% and sweating (59%. Hot flushes, sweating and insomnia were significantly more prevalent in the peri and postmenopausal phases. The frequency (severity of vasomotor and psychological symptoms did not vary according to the menopause phase. The prevalence of urinary incontinence was 27.4%. Complaints of dyspareunia and vaginal dryness were infrequent. Decreased libido was the most frequent sexual complaint. It was observed that some climacteric complaints were interrelated. The first cluster included hot flushes and sweating (vasomotor cluster. The second cluster included nervousness, depression and irritability (psychological cluster. The third cluster included dizziness and palpitation (atypical cluster. CONCLUSION: Climacteric symptoms in this population were highly prevalent and similar to those described in developed Western countries.

  18. [The climacteric and biomedicine: reflections from nursing and the sociology of health and illness disciplines].

    Science.gov (United States)

    Leyva-Moral, Juan Manuel

    2012-03-01

    This article critically examines the biomedical model and how it has influenced the social construction of the meaning of the menopause. This model has been criticized as reductionist since it understands people as entities made of several parts that can be studied separately. Contrarily for nursing, people are formed by several parts in direct relation with the environment and themselves. Therefore, it is not posible to understand people's reality without considering social factors. The menopause has been described in various biomedical texts as a phenomenon similar to a disease, with severe symptoms and negative connotations. However the experiences and meanings that women ascribe to this stage of their life are varied and not always negative. In order to offer appropriate care, it is important for nursing to think about the role of social interaction in constructing the meaning individuals attribute to phenomena.

  19. Differentiated Evaluation of Extract-Specific Evidence on Cimicifuga racemosa's Efficacy and Safety for Climacteric Complaints

    Directory of Open Access Journals (Sweden)

    A.-M. Beer

    2013-01-01

    Full Text Available Past reviews on Cimicifuga racemosa (CR without differentiation between extracts, quality, and indication altogether led to inconsistent data. Therefore, for the first time, we meet the requirements of the system's logic of evidence-based phytotherapy by taking into consideration extracts, pharmaceutical quality (reflected in a regulatory status as medicinal product, and indication. A literature search for clinical studies examining CR's efficacy and safety for menopausal complaints was conducted. The results were sorted by type of extract, regulatory status, and indication. Accordingly, Oxford Levels of Evidence (LOE and Grades of Recommendation (GR were determined. CR extracts demonstrated a good to very good safety in general, on estrogen-sensitive organs and the liver. However, only registered CR medicinal products were able to prove their efficacy. Best evidence was provided by the isopropanolic CR extract (iCR: the multitude of studies including more than 11,000 patients demonstrated consistent confirmatory evidence of LOE 1b (LOE 1a for safety leading to GR A. The studies on the ethanolic extract BNO 1055 including more than 500 patients showed exploratory evidence of LOE 2b resulting in GR B. A positive benefit-risk profile is stated and limited to Cimicifuga racemosa products holding a marketing authorisation for treating climacteric complaints.

  20. The impact of diagnosis and trait anxiety on psychological distress in women with early stage breast cancer : A prospective study

    NARCIS (Netherlands)

    Keyzer-Dekker, Claudia M. G.; de Vries, Jolanda; Mertens, Marlies C.; Roukema, Jan A.; van der Steeg, Alida F. W.

    2014-01-01

    ObjectivesHigh trait anxiety (HTA) determines depressive symptoms and state anxiety in women with breast cancer (BC) or benign breast disease (BBD). Before implementing screening for psychological counselling in these women, it is important to evaluate whether high state anxiety and depressive sympt

  1. Ambivalent sexism and attitudes toward women in different stages of reproductive life: a semantic, cross-cultural approach.

    Science.gov (United States)

    Chrisler, Joan C; Gorman, Jennifer A; Marván, Maria Luisa; Johnston-Robledo, Ingrid

    2014-01-01

    College students in southeastern Mexico (n = 185) and the northeastern United States (n = 96) utilized a semantic differential scale to rate subtypes of women: a menstruating woman, a menopausal woman, a pregnant woman, a premenstrual woman, a woman with a hysterectomy, a teenage girl, a woman in love, and a woman with a young baby. Americans reported significantly more negative attitudes than Mexicans did toward a menstruating woman, a premenstrual woman, a teenage girl, and a pregnant woman. Participants chose more positive words to describe a teenage girl, a woman in love, a pregnant woman, and a woman with a young baby, which is suggestive of a pronatal bias. Participants also completed the Ambivalent Sexism Inventory (ASI). Men scored significantly higher than women on hostile sexism. Mexicans scored significantly higher than Americans on both hostile and benevolent sexism. Sexism scores are related to attitudes toward premenstrual, menstruating, and menopausal women; women with a hysterectomy; and women with a young baby.

  2. Climateric: fatigue or third stage of the general adaptation syndrome Climaterio: fatiga o tercera etapa del síndrome de adaptación general

    OpenAIRE

    William Alvarez Gaviria

    2004-01-01

    The origin of climacteric has been subject of debate. Most opinions agree in that it arises exclusively from natural selection. In this paper the author argues that, besides this reason there is another, even more important; for him, climacteric is the final response to fatigue or the third stage of the general adaptation syndrome, just as in elderly people there is a loss of the capacity of proliferation of fibroblasts and lack of response to insulin. From a genetic point of view, this corre...

  3. Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer.

    Science.gov (United States)

    Witek-Janusek, Linda; Albuquerque, Kevin; Chroniak, Karen Rambo; Chroniak, Christopher; Durazo-Arvizu, Ramon; Mathews, Herbert L

    2008-08-01

    This investigation used a non-randomized controlled design to evaluate the effect and feasibility of a mindfulness based stress reduction (MBSR) program on immune function, quality of life (QOL), and coping in women recently diagnosed with breast cancer. Early stage breast cancer patients, who did not receive chemotherapy, self-selected into an 8-week MBSR program or into an assessment only, control group. Outcomes were evaluated over time. The first assessment was at least 10 days after surgery and prior to adjuvant therapy, as well as before the MBSR start-up. Further assessments were mid-MBSR, at completion of MBSR, and at 4-week post-MBSR completion. Women with breast cancer enrolled in the control group (Non-MBSR) were assessed at similar times. At the first assessment (i.e., before MBSR start), reductions in peripheral blood mononuclear cell NK cell activity (NKCA) and IFN-gamma production with increases in IL-4, IL-6, and IL-10 production and plasma cortisol levels were observed for both the MBSR and Non-MBSR groups of breast cancer patients. Over time women in the MBSR group re-established their NKCA and cytokine production levels. In contrast, breast cancer patients in the Non-MBSR group exhibited continued reductions in NKCA and IFN-gamma production with increased IL-4, IL-6, and IL-10 production. Moreover, women enrolled in the MBSR program had reduced cortisol levels, improved QOL, and increased coping effectiveness compared to the Non-MBSR group. In summary, MBSR is a program that is feasible for women recently diagnosed with early stage breast cancer and the results provide preliminary evidence for beneficial effects of MBSR; on immune function, QOL, and coping.

  4. Prof WANG Xiao-yun's Experience in Treating Climacteric Syndrome from the Pathogenesis of Kidney Deficiency and Liver Stagnancy

    Institute of Scientific and Technical Information of China (English)

    XU Ying; LIU Jian; WANG Xiao-yun

    2010-01-01

    @@ Prof. WANG Xiao-yun, a chief physician in the Second Affiliated Hospital of Guangzhou TCM University (Guangdong Provincial Hospital of TCM), is a leading physician, professor, and the supervisor of doctoral students in the national key subject of TCM gynecology. Having been engaged in TCM gynecological clinical practice and scientific researches for about 30 years, Prof. WANG has obtained rich experience in the treatment of obstinate and miscellaneous diseases of gynecology, especially in the analysis of pathogenesis and differential treatment of climacteric syndrome.

  5. Effect of Inhalation of Aroma of Geranium Essence on Anxiety and Physiological Parameters during First Stage of Labor in Nulliparous Women: a Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Fahimeh Rashidi Fakari

    2015-06-01

    Full Text Available Introduction: Anxiety increases significantly during labor, especially among nulliparous women. Such anxiety may affect the progress of labor and physiological parameters. The use of essential oils of aromatic plants, or aromatherapy, is a non-invasive procedure that can decrease childbirth anxiety. This study examined the effect of inhalation of the aroma of geranium essential oil on the level of anxiety and physiological parameters of nulliparous women in the first stage of labor. Methods: In study, was carried out on 100 nulliparous women admitted to Bent al-Hoda Hospital in the city of Bojnord in North Khorasan province of Iran during 2012-2013. The women were randomly assigned to two groups of equal size, one experimental group (geranium essential oil and one control (placebo group. Anxiety levels were measured using Spielberger’s questionnaire before and after intervention. Physiological parameters (systolic and diastolic blood pressure, respiratory rate, pulse rate were also measured before and after intervention in both groups. Data analysis was conducted using the x2 test, paired t-test, Mann-Whitney U test, and Wilcox on test on SPSS 11.5. Results: The mean anxiety score decreased significantly after inhalation of the aroma of geranium essential oil. There was also a significant decrease in diastolic blood pressure.Conclusion: Aroma of essential oil of geraniums can effectively reduce anxiety during labor and can be recommended as a non-invasive anti-anxiety aid during childbirth.

  6. Prevalence and risk of depressive symptoms 3-4 months post-surgery in a nationwide cohort study of Danish women treated for early stage breast-cancer

    DEFF Research Database (Denmark)

    Christensen, Søren; Zachariae, Robert; Jensen, Anders Bonde

    2009-01-01

    breast cancer during the 2 1/2 year study period. Of these, 3343 women (68%) participated in a questionnaire study 12-16 weeks following surgery. Depressive symptoms (Beck's Depression Inventory II) and health-related behaviors were assessed by questionnaire. The Danish Breast Cancer Cooperative Group......BACKGROUND: Elevated levels of depressive symptoms are generally found among cancer patients, but results from existing studies vary considerably with respect to prevalence and proposed risk factors. PURPOSE: To study the prevalence of depressive symptoms and major depression 3-4 months following...... surgery for breast cancer, and to identify clinical risk factors while adjusting for pre-cancer sociodemographic factors, comorbidity, and psychiatric history. PATIENTS AND METHODS: The study cohort consists of 4917 Danish women, aged 18-70 years, receiving standardized treatment for early stage invasive...

  7. Exploring the effects of second stage management from the maternal and midwifery perspectives: are there any benefits to directing women?

    OpenAIRE

    Cooper, Kerry

    2016-01-01

    Background: The management of second stage varies considerably, with directed pushing, by recourse to Valsalva Technique or a variation of this, being frequently utilised as a replacement for progression through spontaneous maternal effort. The evidence for directed management versus spontaneous is unclear. \\ud Objectives: This review aims to consider the effects of directed pushing on maternal perspectives of second stage management and to assess midwives’ attitudes in relation to this in di...

  8. Effect of Compound Recipe Gengniankang (更年康) on Senile Sexual Hormone and Expression of Estrogen Receptor in Bone of Climacteric Female Rats

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Objective: To compare the therapeutic effect of Compound Recipe Gengniankang (更年康,GNK) with that of hormone replacement treatment (HRT) on climacteric female rats with osteoporosis, and to investigate the roles of estrogen and estrogen receptors in the mechanism of osteoporosis. Methods: Climac-teric female rats with osteoporosis were chosen and divided into three groups (GNK group, HRT group and control group). Apoptosis of ovarian granulose cells was measured by terminal-deoxynucleotidyl transferae mediated nick end labeling (TUNEL) assay. Serum level of estrdiol (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH) were determined by the method of radioimmunoassay (RIA). Reverse transcriptase polymerase chain reaction (RT-PCT) technology was used to evaluate the expression of estrogen receptor (ER) in bone. Bone mineral density (BMD) was measured by double energy X-ray absorption (DEXA). Results: In the climacteric rats, BMD, serum E2, ER mRNA expression in bone decreased remarkably, and serum FSH, LH and apoptosis of ovarian granulose cells increased obviously. After treating with GNK, all the indexes were reversed except serum E2. The increase of E2 was not significant. Conclusion:GNK is effective on climacteric osteoporosis female rats. Its role is performed not by increasing serum E2 but by enhancing ER in the bone and inhibiting apoptosis of ovarian granulose cells. GNK can deter further exhaustion of ovarian function.

  9. Review of preoperative magnetic resonance imaging (MRI) in breast cancer: should MRI be performed on all women with newly diagnosed, early stage breast cancer?

    Science.gov (United States)

    Houssami, Nehmat; Hayes, Daniel F

    2009-01-01

    Randomized controlled trials have shown equivalent survival for women with early stage breast cancer who are treated with breast-conservation therapy (local excision and radiotherapy) or mastectomy. Decades of experience have demonstrated that breast-conservation therapy provides excellent local control based on defined standards of care. Magnetic resonance imaging (MRI) has been introduced in preoperative staging of the affected breast in women with newly diagnosed breast cancer because it detects additional foci of cancer that are occult on conventional imaging. The median incremental (additional) detection for MRI has been estimated as 16% in meta-analysis. In the absence of consensus on the role of preoperative MRI, we review data on its detection capability and its impact on treatment. We outline that the assumptions behind the adoption of MRI, namely that it will improve surgical planning and will lead to a reduction in re-excision surgery and in local recurrences, have not been substantiated by trials. Evidence consistently shows that MRI changes surgical management, usually from breast conservation to more radical surgery; however, there is no evidence that it improves surgical care or prognosis. Emerging data indicate that MRI does not reduce re-excision rates and that it causes false positives in terms of detection and unnecessary surgery; overall there is little high-quality evidence at present to support the routine use of preoperative MRI. Randomized controlled trials are needed to establish the clinical, psychosocial, and long-term effects of MRI and to show a related change in treatment from standard care in women newly affected by breast cancer.

  10. Birthing positions during second stage of labor and long-term psychological outcomes in low-risk women

    NARCIS (Netherlands)

    Jonge, A. de; Rijnders, M.E.B.; Diem, M.T. van; Scheepers, P.L.H.; Lagro-Janssen, A.L.M.

    2011-01-01

    PURPOSE: To examine the long-term influence of birthing positions during the second stage of labor, as well as other factors, on birth satisfaction, self-esteem (based on the Rosenberg Self-esteem Scale [RSE]) and emotional well-being (based on the Edinburgh Postnatal Depression Scale [EPDS]). STUDY

  11. Effects of Xuefu Zhuyu Oral Liquid on climacteric osteoporosis%血府逐瘀口服液对更年期骨质疏松的康复作用

    Institute of Scientific and Technical Information of China (English)

    宾红; 岳楠

    2003-01-01

    @@ INTRODUCTION Osteoporosis is a complication of climacteric syndrome. Preventionand rehabilitative treatment to climacteric syndrome are advocated atpresent. Current method of treatment is hormonal replacement ther-apy or the traditional Chinese medicine therapy aiming at invigora-tion and health protection. Though effects the hormonal replacementtherapy does, it also risks of higher incidence rate of mammarycancer and carcinoma of corpus uteri with improper using[1 -3] . Sodrug treatment without side effect is desirable. Application of XuefuZhuyu Oral liquid is good to climacteric osteoporosis.

  12. PROBLEMATIC ISSUES OF DIAGNOSTICS AND THERAPY OF NON-PSYCHOTIC MENTAL DISORDERS IN FEMALE PATIENTS OF CLIMACTERIC AGE WITH HYSTERICAL SYMPTOM COMPLEX (LITERATURE REVIEW

    Directory of Open Access Journals (Sweden)

    Ye. V. Lukiyanova

    2013-01-01

    Full Text Available In the article, problematic questions of diagnostics and therapy of non-psychotic mental disorders (NPMD in female patients of climacteric age with hysterical symptom complex are considered. Efficacy of psychotherapy (PT in NPMD, hypnopsychotherapy in hysterical states: hysterical neurosis, neurasthenia and obsessive-compulsive neurosis is indicated. In treatment of NPMD, PT by creative selfexpression is successfully used. It is highlighted that PT forms conscious-critical attitude of patients toward themselves. Combination of PT with physiotherapy in hysterical conversional symptoms has been described. In hysterical manifestations neuroleptics are recommended, in neurotic depressions – antidepressants of mild action. In severe hysterical state, psychopharmacotherapy (PPhT with tranquilizers and neuroleptics is applied on long-term basis. Stable recovery in dissociative and hysterical disorders has been shown. In vegetovascular disorders in structure of climacteric syndrome (CS vinpocetine, in psychoemotional manifestations phenibut was administered. In therapy of hysterical neurosis, “minor neuroleptics”, hypnosuggestive therapy, social rehabilitation were applied. Effective group PT of psychogenically conditioned disorders in asthenicand anxiety-depressive symptoms is effective. Complex therapy of NPMD in hysterical and asthenic neurosis, obsessive-compulsive neurosis has been suggested. Organization of specialized preventive examinations for early revealing of persons with personality pathology is based. Efficacy of a number of medications in periand post-menopause – SSRIs and gabapentin, during menopause paroxetine, in depressions of non-psychotic level – pyrazidol, coaxil, in neurotic hypochondriasis sulpiride and quetiapine, diazepam, in climacteric vegetative and mental disorders hormone replacement therapy (HRT, hormonal therapy, PPhT and PT, in neurovegetative symptoms of CS – antidepressants, in psychovegetative syndromes

  13. Development in self-reported arm-lymphedema in Danish women treated for early-stage breast cancer in 2005 and 2006 – A nationwide follow-up study

    DEFF Research Database (Denmark)

    Gärtner, Rune; Mejdahl, Mathias Kvist; Andersen, Kenneth Geving

    2014-01-01

    The main purpose of this nationwide follow-up study was to examine the development of self-reported lymphedema in the population of women with early-stage breast cancer in Denmark. In 2008 and 2012 two identical questionnaires were sent to the women aged 18-70 years treated for unilateral primary...... breast cancer in 2005 and 2006. 2293 women (87%) reported on lymphedema in 2008 and 2012. Overall 37% reported lymphedema in 2008 while 31% reported lymphedema in 2012 and severity of symptoms decreased. 50% of women treated with SLNB and reporting lymphedema in 2008 did not report symptoms by 2012...... in contrast to 30% treated with ALND. However, 19% of women treated with ALND and not reporting lymphedema in 2008 had developed lymphedema by 2012. In conclusion lymphedema remains a frequent problem, years after treatment for breast cancer, though, number of women reporting lymphedema and overall severity...

  14. Clinical Observation of Combined Acupuncture and Herbs in Treating Low Back Pain due to Climacteric Osteoporosis in 40 Cases

    Institute of Scientific and Technical Information of China (English)

    WANG Ning; XIAO Yuan-chun

    2004-01-01

    针刺双侧风池、大椎、膈俞、天宗及阿是穴,配合内服中药,治疗40例更年期骨质疏松腰背痛患者,治愈25例,好转9例,无效6例,总有效率85.0%.%Forty cases of low back pain due to climacteric osteoporosis were treated by needling Fengchi (GB 20), Dazhui (GV 14), Geshu (BL 17), Tianzong (SI 11) and Ashi points, as well as oral Chinese herbs. Results showed cure in 25 cases, improvement in 9 cases and failure in 6 cases, with the total effective rate of 85.0%.

  15. Complementary and alternative therapies for treatment of insomnia in women in postmenopause.

    Science.gov (United States)

    Hachul, H; Monson, C; Kozasa, E H; Oliveira, D S; Goto, V; Afonso, R; Llanas, A C; Tufik, S

    2014-12-01

    Menopause is an important episode in the life of women and, for the great majority of women, occurs in their fifties. The climacteric period, which is often associated with insomnia, represents one of the most important changes in the female reproductive cycle because it marks the end of reproductive capacity. Hormonal therapy has been considered the most useful and standardized method for treating menopause and climacteric-associated symptoms despite its side-effects. The present study is a review of the scientific literature about the efficacy, toxicity and safety of complementary and alternative therapies used as alternatives to hormone therapy to treat insomnia in menopausal women. Mind-body therapies and the use of isoflavonoids have exhibited promise as interventions for treating insomnia in the climacteric at our Walk-In Clinic of Sleep Disturbance at the Universidade Federal de São Paulo. This review will describe the use of complementary and alternative therapies and their effectiveness in treating insomnia in this period of a woman's life.

  16. Physical rehabilitation as the base component of treatment and rehabilitation women sick with gonarthrosis of the third radiological stages of disease

    Directory of Open Access Journals (Sweden)

    Andriychuk O.Y.

    2012-08-01

    Full Text Available The rehabilitations of women, patients given in relation to the programs are resulted, on gonarthrosis to the roentgenologic stage. The changes of indexes expressed of the pain feeling are analysed, morning constraint, pain index and amplitude of motions in joints for patients. 132 patients took part in research. As an index of amplitude of motions information of the active unbending was utillized in a knee-joint. Testing was conducted in three months and six months. Probed and determined a pain index at passive and active motions in a knee. The complex program of physical rehabilitation is offered. The program included a medical physical culture, massotherapy, mechanotherapy, physiotherapy, dietotherapy, psychological support and educational programs. Rehabilitation on the author program set positive changes intensity of the pain feelings, morning constraint, pain index and amplitude of motions, in a knee.

  17. Clinical outcome analysis of 98 elderly women with early-stage breast cancer undergoing modified radical mastectomy or simple mastectomy

    Institute of Scientific and Technical Information of China (English)

    Zhilong Jia; Baoxia Su

    2012-01-01

    Objective: The aim of our study was to analyze the clinical results and prognosis for early elderly patients after surgery and to explore the rational treatment. Methods: Between January 1992 and December 2008, 98 early elderly breast cancer patients aged ≥ 65 years were treated with surgery, of which 52 patients received modified radical mastectomy and 46 patients received simple mastectomy. Results: Sixty-four (65.3%) patients had comorbidities including coronary heart disease, hypertension, diabetes, etc. After a median follow up of 56 months (21 to 280 months), the 5-year cumulative survival rate of breast modified radical mastectomy group and mastectomy group were 84.0% and 82.7%, separately (P = 0.653). The 5-year recurrence rate were 3.8% and 8.1%, separately (P = 0.504). Conclusion: The simple mastectomy is suitable for the treatment of early elderly breast cancer patients for its lower complication and recurrence rate. Early old women with breast cancer may be safely treated by simple mastectomy. Our findings suggest that modified radical mastectomy does not significantly increase the overall survival.

  18. Methylation of BRCA1 promoter region is associated with unfavorable prognosis in women with early-stage breast cancer.

    Science.gov (United States)

    Hsu, Nicholas C; Huang, Ya-Fang; Yokoyama, Kazunari K; Chu, Pei-Yi; Chen, Fang-Ming; Hou, Ming-Feng

    2013-01-01

    BRCA1-associated breast cancers are associated with particular features such as early onset, poor histological differentiation, and hormone receptor negativity. Previous studies conducted in Taiwanese population showed that the mutation of BRCA1 gene does not play a significant role in the occurrence of breast cancer. The present study explored methylation of BRCA1 promoter and its relationship to clinical features and outcome in Taiwanese breast cancer patients. Tumor specimens from a cohort of 139 early-stage breast cancer patients were obtained during surgery before adjuvant treatment for DNA extraction. Methylation of BRCA1 promoter region was determined by methylation-specific PCR and the results were related to clinical features and outcome of patients using statistical analysis. Methylation of the BRCA1 promoter was detected in 78 (56%) of the 139 tumors. Chi-square analysis indicated that BRCA1 promoter methylation correlated significantly with triple-negative (ER-/PR-/HER2-) status of breast cancer patients (p = 0.041). The Kaplan-Meier method showed that BRCA1 promoter methylation was significantly associated with poor overall survival (p = 0.026) and disease-free survival (p = 0.001). Multivariate analysis which incorporated variables of patients' age, tumor size, grade, and lymph node metastasis revealed that BRCA1 promoter methylation was associated with overall survival (p = 0.027; hazard ratio, 16.38) and disease-free survival (p = 0.003; hazard ratio, 12.19) [corrected].Our findings underscore the clinical relevance of the methylation of BRCA1 promoter in Taiwanese patients with early-stage breast cancer.

  19. Health condition of women with mental disorder

    Directory of Open Access Journals (Sweden)

    Nadja Cristiane Lappann Botti

    2014-01-01

    Full Text Available This research aimed to evaluate the reproductive, gynecological, sexual and clinical aspects of women with mental disorders. This is an exploratory research with quantitative approach performed in a Psychosocial Care Center, Type III, in Divinópolis, Minas Gerais, Brazil, with 39 women with mental disorders. Data collection took place from October to December 2012, through used semi-structured interviews and checked blood pressure, blood glucose, weight and height. The results revealed normal levels of blood pressure and postprandial blood glucose, change in body mass index, presence of menstrual flow, nulliparity, first sexual intercourse in adolescence, early menarche, and lack of climacteric symptoms and history of abortion. Comprehensive health care for women involves more than the demands and needs of the mental health field.

  20. Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline

    Science.gov (United States)

    Harris, Lyndsay N.; McShane, Lisa M.; Andre, Fabrice; Collyar, Deborah E.; Gonzalez-Angulo, Ana M.; Hammond, Elizabeth H.; Kuderer, Nicole M.; Liu, Minetta C.; Mennel, Robert G.; Van Poznak, Catherine; Bast, Robert C.; Hayes, Daniel F.

    2016-01-01

    Purpose To provide recommendations on appropriate use of breast tumor biomarker assay results to guide decisions on adjuvant systemic therapy for women with early-stage invasive breast cancer. Methods A literature search and prospectively defined study selection sought systematic reviews, meta-analyses, randomized controlled trials, prospective-retrospective studies, and prospective comparative observational studies published from 2006 through 2014. Outcomes of interest included overall survival and disease-free or recurrence-free survival. Expert panel members used informal consensus to develop evidence-based guideline recommendations. Results The literature search identified 50 relevant studies. One randomized clinical trial and 18 prospective-retrospective studies were found to have evaluated the clinical utility, as defined by the guideline, of specific biomarkers for guiding decisions on the need for adjuvant systemic therapy. No studies that met guideline criteria for clinical utility were found to guide choice of specific treatments or regimens. Recommendations In addition to estrogen and progesterone receptors and human epidermal growth factor receptor 2, the panel found sufficient evidence of clinical utility for the biomarker assays Oncotype DX, EndoPredict, PAM50, Breast Cancer Index, and urokinase plasminogen activator and plasminogen activator inhibitor type 1 in specific subgroups of breast cancer. No biomarker except for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 was found to guide choices of specific treatment regimens. Treatment decisions should also consider disease stage, comorbidities, and patient preferences. PMID:26858339

  1. A study of menopausal symptoms in relation to habits of smoking and make-up using in Japanese women aged 35-59.

    Science.gov (United States)

    Oi, N; Ohi, K

    2012-08-01

    We conducted a survey to elucidate the influence with menopause symptoms and the impact of not only smoking but also using make-up among for Japanese women, included ages above and below the menopausal generation. The subjects of this study were 335 Japanese women from 35 to 59 years of age who were examined for the first time in the specialized women's outpatient clinic of our institution from July 2010 to June 2011 for 1 year period. We used the items of the Menopause-Specific Quality of Life Questionnaire. Similarly, we analysed the scores in relation to menopausal symptoms and whether the subject smoked, whether the subject used make-up depend on women (including foundation, lip rouge, brush one's eyebrows), how frequently she used make-up. The JMP version 9.0 software program was used to statistically analyse the score data. Significant associations were observed in psychosocial (P = 0.0196), tended to be more severe in women before menopause and after climacteric. Furthermore, the frequency of using make-up were negative relations with menopause symptoms (P = 0.0251) after climacteric. Smoking had made worse for physical symptoms (P psychological symptoms. Also, physical conditions were influenced by smoking. Using make-up frequently was often seen after climacteric because of appearance changes by oestrogen dynamic decline.

  2. Non-Destructive Assessment of Aroma Volatiles from a Climacteric Near-Isogenic Line of Melon Obtained by Headspace Stir-Bar Sorptive Extraction

    Science.gov (United States)

    Fernández-Trujillo, Juan Pablo; Dos-Santos, Noelia; Martínez-Alcaraz, Rocío; Le Bleis, Inés

    2013-01-01

    A climacteric aromatic near-isogenic line (NIL) of melon (Cucumis melo L.) SC3-5-1 contained an introgression of the non-climacteric Korean cultivar “Shongwan Charmi” accession PI 161375 (SC) in the genetic background of the non-climacteric cultivar “Piel de Sapo” (PS). The aroma production was monitored during ripening at 21 °C in intact fruit using headspace sorptive bar extraction (HSSE). Bars were composed of polydimethylsiloxane (PDMS) and aromas were desorbed and analyzed by gas-chromatography mass-spectrometry. The aromatic profile was composed of 70 aromatic compounds plus 21 alkanes with a predominance of esters, particularly acetate (2-methylbutyl acetate, 2-methylpropyl acetate, hexyl acetate, and phenylmethyl acetate). Some compounds were severely affected by postharvest time. The acetate esters (3-methylbutyl acetate, butan-2-yl acetate and phenylmethyl acetate) decreased with ripening and sulfur-derived compounds (S-methyl butanethioate and S-methyl 3-methylbutanethioate) increased gradually with ripening. A few compounds increased at the senescence phase (propyl ethanoate). Other compounds such as hexadecanoic acid showed a marked decrease after harvest, some decreasing from a relative maximum at harvest (2-methylpropyl hexanoate; n-hexanoic acid; nonanoic acid).

  3. Second stage of labor.

    Science.gov (United States)

    Cheng, Yvonne W; Caughey, Aaron B

    2015-06-01

    Current American College of Obstetricians and Gynecologists' definition of prolonged second stage diagnoses 10% to 14% of nulliparous and 3% to 3.5% of multiparous women as having a prolonged second stage. The progression of labor in modern obstetrics may have deviated from the current labor norms established in the 1950s, likely due to differences in obstetric population characteristics and variation in clinical practice. Optimal management of the second stage in women with and without epidural remains debatable. Although prolonged second stage is associated with increased risk of maternal morbidity, conflicting data exist regarding the duration of second stage and associated neonatal morbidity and mortality.

  4. Hormone replacement therapy and hypercoagulability. Results from the Prospective Collaborative Danish Climacteric Study

    DEFF Research Database (Denmark)

    Sidelmann, Johannes Jakobsen; Jespersen, Jørgen; Andersen, Lars F.

    2003-01-01

    , Hellerup, and Rigshospitalet, Copenhagen, Denmark. POPULATION: One hundred and forty-nine postmenopausal women without previous venous thromboembolic disease. METHODS: Prothrombin fragment 1+2 (F(1+2)), fibrin degradation products, antithrombin, protein C, total protein S and activated protein C...... manifestations in thrombosis-prone individuals....

  5. Study for the change of health-related quality of life in women with early stage breast cancer, one year after the diagnosis

    Directory of Open Access Journals (Sweden)

    Vasiliki E. Kοutsopοulοu-Sofikiti

    2010-01-01

    Full Text Available Health - related quality of life of women with breast cancer is defined as the subjective evaluation of the effect of the disease and its treatment to physical, psychological and social level of functioning and well-being.The aim of the present study was to estimate the change of health- related quality of life at patients with early- stage breast cancer one year after the diagnosis and the initial therapeutic intervention.Material – method: The material of the study was 181 patients age between 28 to 88 years with breast cancer stage II. The entry criteria were: 1 females with breast cancer stage II, who would have been in need of adjuvant therapy after the initial operational intervention. 2 Moreover, they should not have been hospitalized for the same reason in the past and they should have a satisfying ability in communication. The data collection was made with the use of the QLQ C-30 questionnaire of the European Organization for the Research and Treatment of Cancer (EORTC in association with the module for the breast cancer (module Br23.The data collection was realized through interviews conducted by the researchers at two different time points: at the diagnosis point and the one year after the diagnosis. It was an easy sample.Results: To sum up, health- related quality of life was estimated as worse in the first year after diagnosis and the initial therapeutic intervention. Furthermore, remarkable was, the deterioration of symptoms (fatigue, pain, nausea, sleep loss, appetite loss, constipation, dyspnoea. The deterioration was also visible to the patients’ body image and to the treatment side effects of adjuvant therapies.Conclusions: The breast cancer influences negatively health- related quality of life in patients with early stage breast cancer. After the completion of the adjuvant therapies, there are major problems like fatigue, pain and aggravated body image, which make patients suffer. The altered body image provokes stress and

  6. Evaluation Of Hormone Profile And Dexa Values in Premenopausal, Perimenopausal and Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Esra Esen

    2005-09-01

    Full Text Available This study was carried out in 130 women, between 44-55 ages, admitted to outpatient clinic of Physical Medicine and Rehabilitation Department of Trakya University Medical Faculty in order to make. comparison of hormone profile and DEXA values of premenopausal, perimenopausal, and postmenopausal women . Three groups were allocated according to climacteric symptoms and menopause condition. Premenopausal group consisted of women who had regular menstruation and did not have any climacteric symptoms , perimenopausal group consisted of women who had menstruation disorder and climacteric symptoms within one year and postmenopausal group consisted of women who had last menstruation within more than one year and less than 5 years. Women who had prior osteoporosis diognosis and treatment, hormone replacement therapy, surgical menopause and menopause duration more than 5 years were excluded from the study. Age, body weight ,height, hormone profile including estradiol (E2, progesterone (P, follicule stimulating hormone (FSH, luteinizing hormone (LH, parathyroid hormone (PTH, thyroid hormones (T3, T4, thyroid stimulating hormone (TSH and DEXA values representing bone mineral density (BMD of both groups were evaluated. In peri and postmenopausal groups, E2, P, FSH and LH values were significantly lower, while there was no significant difference for PTH and thyroid hormone levels comparing to premenopausal group. For DEXA values, T scores of L2-L4, L2, L3, L4, femur neck, trochanter, Wards and Z scores of femur neck, Wards area were significantly lower in peri and postmenopausal groups. It was demonstrated paralel to literature that BMD decreased in peri and early postmenopausal women associated with hormone profile changes, mainly lower E2.

  7. Efeitos do Trifolium pratense nos sintomas climatéricos e sexuais na pós-menopausa Effects of Trifolium pratense on the climacteric and sexual symptoms in postmenopause

    Directory of Open Access Journals (Sweden)

    Cecília Del Giorno

    2010-01-01

    Full Text Available OBJETIVO: Avaliar os efeitos do tratamento com Trifolium pratense nos sintomas climatéricos e na satisfação sexual de mulheres na pós-menopausa. MÉTODOS: Este estudo foi prospectivo, randomizado, duplo-cego e controlado com placebo. Foram selecionadas 120 mulheres na faixa etária de 45 anos a 65 anos com sintomas climatéricos, amenorreia superior a um ano e sem tratamento nos últimos seis meses. Após a seleção, foram divididas em dois grupos: GT -receberam Trifolium pratense na dose de 40 mg, 1 capsula/dia; GP -receberam placebo (controle, contendo lactose, 1 cápsula/dia. A duração do tratamento foi de 12 meses. As pacientes foram avaliadas clinica e laboratorialmente antes do tratamento e com quatro, oito e 12 meses de tratamento. Foi empregado também o Índice Menopausal de Kupperman (IMK e o Inventário de Satisfação Sexual Golombok Rust. No final do estudo, cada grupo tinha 50 pacientes. RESULTADOS: Houve melhora significante dos sintomas menopausais após quatro meses de tratamento pelo IMK, principalmente em relação aos fogachos, comparando os dados antes do tratamento nos dois grupos, porém, não houve diferença significante entre os grupos. Não houve melhora na sexualidade antes e após o tratamento. CONCLUSÃO: O tratamento por 12 meses com Trifolium pratense, na dose de 40mg/dia, não promoveu melhora significante dos sintomas menopausais e na satisfação sexual.OBJECTIVE: To evaluate effects of treatment with Trifolium pratense on climacteric symptoms and sexual satisfaction in postmenopausal women. METHODS: This study was prospective, randomized, double-blind and placebo-controlled. We selected 120 women, aged between 45 and 65 years with climacteric symptoms, with absence of menstruation (amenorrhea for more then one year and without any treatment in the last six months. After selection, women were divided into two groups: GT received 40 mg of Trifolium pratense (one capsule per day; GP received placebo

  8. The Effects of Nutritional Juice Supplementation on the Extent of Climacteric Symptoms: An Observational Study

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    Stefanie I. Siebler

    2016-01-01

    Full Text Available Objective. This study aims to evaluate the effect of daily dietary nutritional supplement on somatic, psychological, and urogenital symptoms in postmenopausal women. Material and Methods. In this study 28 healthy, symptomatic, peri- and postmenopausal women of 47–67 years of age were allocated to use the nutritional supplement JuicePLUS+®. Primary research parameters: Menopause Rating Scale (MRS was used to assess menopausal symptoms at baseline and after 8 and 16 weeks of treatment. Secondary parameters: proliferation behaviour of vaginal smear was scored at baseline and after treatment. Results. Treatment with the supplement resulted in a reduction of somatic, psychological, and urogenital symptoms. The overall MRS score showed an average improvement of 44.01%. Most benefits were observed for the psychological symptoms irritability (60.55% and physical and mental exhaustion (49.08%; modest effects were observed for hot flashes (44.86% and sleeping problems (35.56%. There was a minor improvement in sexual problems; 6 women reported an increased libido. No statistically significant effect was found in vaginal dryness and proliferation behaviour of vaginal mucosa. No adverse effects were observed. Conclusion. Dietary nutritional supplement may constitute an effective alternative therapy to conventional alternative medicine for somatic, psychological, and sexual symptoms.

  9. Establishment of Climacteric Hypertension Dryness Syndrome Model in Rats%更年期高血压燥证大鼠模型的构建

    Institute of Scientific and Technical Information of China (English)

    葛丽; 林雪; 李鸿霞

    2015-01-01

    Objective To explore the method of the establishment of climacteric hypertension dryness syndrome model in rats.Methods A total of 12 female spontaneously hypertensive rats ( SHR) were selected as study subjects from January to March in 2014, SHR were randomly divided into climacteric hypertension group and climacteric hypertension dryness syndrome model group , there were 6 rats in each group.The bilateral ovaries of rats were removed by surgery , thus climacteric hypertension rats were obtained.Rats in climacteric hypertension dryness syndrome model group were placed in artificial dryness syndrome environment, and were fed with food from northwest area which may cause dryness syndrome.The biological characteristics (coat color, mental state, degrees of excitement, food intake, water intake, body mass, characters of urine and stool, tongue picture, claws picture), serum levels of neurotransmitters 〔corticotropin -releasing hormone ( CRH), adrenocorticotrophic hormone (ACTH), norepinephrine (NE), dopamine (DA), 5 -hydroxytryptamine (5 -HT)〕 and hormones 〔estradiol (E2), testosterone ( T)〕, and histological changes of organs ( liver, spleen, adrenal gland, and hypothalamus ) were observed and recorded.Results Compared with rats in climacteric hypertension group , the body mass and urine volume were significantly decreased , and water intake was significantly increased among rats in climacteric hypertension dryness syndrome model group, the differences were statistically significant ( P 0.05) .Compared with rats in climacteric hypertension group, serum levels of E2 and T were significantly decreased , and E2/T was significantly increased among rats in climacteric hypertension dryness syndrome model group , the differences were statistically significant (P<0.05) .The significant histological changes of liver , spleen, adrenal gland, and hypothalamus were observed among two groups of rats.Conclusion The artificial dryness syndrome environment , food from

  10. Knowledge, non-use, use and source of information on contraceptive methods among women in various stages of reproductive age in rural Lagos, Southwest Nigeria

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    Afolabi BM

    2015-05-01

    Full Text Available Bamgboye M Afolabi,1 Emmanuel NU Ezedinachi,2 Iwara Arikpo,2 Abiodun Ogunwale,3 Damilola Fatimah Ganiyu,1 Rashidat A Abu,1 Adewunmi A Ajibade1 1Health, Environment and Development Foundation, Yaba, Lagos, Nigeria; 2Institute of Tropical Disease and Research, University of Calabar, Calabar, Nigeria; 3Project Hope, Washington, DC, USA Background: Contraceptives are advocated to be used against unwanted pregnancy and sexually transmitted diseases as unsafe abortion contributes to high maternal mortality in Nigeria while unwanted pregnancies have terminated the educational development of many females. Objective: This questionnaire-based survey aimed to describe the knowledge, nonuse, and use of various contraceptive methods among women in different child-bearing age groups in rural Lagos, Nigeria. Materials and methods: Between 2012 and 2013, 816 females in rural communities within Lagos State were surveyed for their knowledge, source of information, and use of contraceptives. They were grouped into early, mid, and late reproductive age. Statistical analysis of data harvested from respondents was carried out using STATA 13 software. Results: In all, 816 females in different stages of reproductive age were involved in the study, among whom 19% were single, 78% married, 3% divorced, and 0.5% widowed. About 6% had no formal education, while the majority (81% were of the Yoruba ethnic group. Married respondents were approximately thrice more likely to know of contraceptives than single respondents (χ2=29.9, P=0.000, odds ratio =2.9, 95% confidence interval =1.9, 4.2. Condom use was the most widely known and used method of contraceptive regardless of marital status and reproductive age status. Information about contraceptives was mainly from health facilities among married and divorced women and from school or educational institution among singles. Overall prevalence of contraceptive use was 51.9%. Nonuse of contraceptives was 43% among married women

  11. Conhecimento, percepções e assistência à saúde da mulher no climatério Conocimiento, percepciones y asistencia a la salud de la mujer en lo climaterio Knowledge, perceptions and assistance to woman's health in the climacteric

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    Neiva Iolanda de Oliveira Berni

    2007-06-01

    Full Text Available As vivências do climatério foram o objeto deste estudo, em pesquisa descritivo-qualitativa com mulheres das cidades de Canoas e Porto Alegre, RS. A coleta de informações utilizou entrevista semi-estruturada em 15 mulheres entre 41 e 59 anos de idade. A interpretação e análise basearam-se na análise de conteúdo. As mulheres expressam confusão sobre o significado do climatério, relacionando-o aos sintomas que associam ao envelhecimento. Reconhecem tratar-se de uma fase da vida com aspectos também positivos e a vivem sem maiores preocupações.As percepções das mulheres sobre o climatério são fragmentadas e a assistência médica o trata como doença passível de tratamento. Portanto, o profissional enfermeiro, pela presença interativa constante na vida dessas mulheres, pode ajudar a desmistificar e ressignificar esse processo na vida da mulher.Las vivencias del climaterio fueron el objeto de este estudio, en investigación descriptiva-cualitativa con mujeres de las ciudades de Canoas y Porto Alegre, RS. La recolección de informaciones utilizó entrevista semiestructurada con 15 mujeres entre 41 y 59 años de edad. La interpretación y el análisis se basaran en el análisis de contenido. Las mujeres expresan confusión acerca del significado de climaterio, relacionándolo con los síntomas que asociados al envejecimiento. Reconocen tratarse de una fase de la vida con aspectos también positivos y la viven sin mayores preocupaciones. Las percepciones de las mujeres acerca del climaterio son fragmentadas y la asistencia médica lo trata como enfermedad factible de tratamiento. Por lo tanto, el profesional enfermero, por su presencia interactiva constante en la vida de esas mujeres, puede ayudar a desmistificar y a re-significar ese proceso en la vida de la mujer.The experience of the climacteric period is the object of the present descriptive-qualitative study with women from the cities of Canoas and Porto Alegre, RS. The

  12. Reflections on sexuality during the climacteric Reflexiones sobre la sexualidad durante la vivencia del climaterio Reflexões sobre a sexualidade durante a vivência do climatério

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    Roselane Gonçalves

    2009-04-01

    Full Text Available Qualitative and phenomenological study based on reports of women between 48 and 55 years old with spontaneous menopause for 12 months or more. Results evidenced five theme categories that were analyzed and interpreted based on Maurice Merleau-Ponty's theoretical-philosophical reference framework. Among the categories that emerged from reports, the theme "reflecting on sexuality" was emphasized, and is presented with a view to understanding the existential aspects of the climacteric experience, focusing on the exercise of sexuality.Se trata de un estudio cualitativo de abordaje fenomenológico, realizado a partir del relato de mujeres con edad entre 48 y 55 años que habían presentado menopausia espontánea hace 12 meses o más. Los resultados mostraron cinco categorías temáticas que fueron analizadas e interpretadas con base en el marco teórico filosófico de Maurice Merleau-Ponty. Entre las categorías que surgieron de los relatos sobresalió el tema" Reflexionando sobre la sexualidad" que será presentado con el objetivo de comprender los aspectos existenciales de la vivencia del climaterio con énfasis en la sexualidad.Estudo qualitativo de abordagem fenomenológica, realizado a partir do depoimento de mulheres entre 48 e 55 anos que haviam apresentado menopausa espontânea há 12 meses ou mais. Os resultados evidenciaram cinco categorias temáticas que foram analisadas e interpretadas à luz do referencial teórico filosófico de Maurice Merleau-Ponty. Dentre as categorias que emergiram dos depoimentos destacou-se o tema: "refletindo sobre a sexualidade", que será apresentado com o objetivo de compreender os aspectos existenciais da vivência do climatério com ênfase no exercício da sexualidade.

  13. Diabetes mellitus as a risk factor for incident chronic kidney disease and end-stage renal disease in women compared with men: a systematic review and meta-analysis.

    Science.gov (United States)

    Shen, Yanjue; Cai, Rongrong; Sun, Jie; Dong, Xue; Huang, Rong; Tian, Sai; Wang, Shaohua

    2017-01-01

    Diabetes mellitus is a strong risk factor for chronic kidney disease and end-stage renal disease. Whether sex differences in chronic kidney disease and end-stage renal disease incidence exist among diabetic patients remains unclear. This systematic review and meta-analysis was conducted to evaluate the relative effect of diabetes on chronic kidney disease and end-stage renal disease risk in women compared with men. We systematically searched Embase, PubMed, and the Cochrane Library for both cohort and case-control studies until October 2015. Studies were selected if they reported a sex-specific relationship between diabetes mellitus and chronic kidney disease or end-stage renal disease. We generated pooled estimates across studies using random-effects meta-analysis after log transformation with inverse variance weighting. Ten studies with data from more than 5 million participants were included. The pooled adjusted risk ratio of chronic kidney disease associated with diabetes mellitus was 3.34 (95 % CI 2.27, 4.93) in women and 2.84 (95 % CI 1.73, 4.68) in men. The data showed no difference in diabetes-related chronic kidney disease risk between the sexes (pooled adjusted women-to-men relative risk ratio was 1.14 [95 % CI 0.97, 1.34]) except for end-stage renal disease-the pooled adjusted women-to men relative risk ratio was 1.38 (95 % CI 1.22, 1.55; p = 0.114, I² = 38.1 %). The study found no evidence of a sex difference in the association between diabetes mellitus and chronic kidney disease. However, the excess risk for end-stage renal disease was higher in women with diabetes than in men with the same condition, from which we assume that the female gender could accelerate the disease progression. Further studies are needed to support this notion and elucidate the underlying mechanisms.

  14. "I should live and finish it": A qualitative inquiry into Turkish women's menopause experience

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    Unalan Pemra C

    2009-01-01

    Full Text Available Abstract Background While bio-medically, menopause could be treated as an illness, from a psychosocial and cultural perspective it could be seen as a "natural" process without requiring medication unless severe symptoms are present. Our objective is to explore the perceptions of Turkish women regarding menopause and Hormone Therapy (HT to provide health care workers with an insight into the needs and expectations of postmenopausal women. Methods A qualitative inquiry through semi-structured, in-depth interviews was used to explore the study questions. We used a purposive sampling and included an equal number of participants who complained about the climacteric symptoms and those who visited the outpatient department for a problem other than climacteric symptoms but when asked declared that they had been experiencing climacteric symptoms. The interview questions focused on two areas; 1 knowledge, experiences, attitudes and beliefs about menopause and; 2 menopause-related experiences and ways to cope with menopause and perception of HT. Results Most of the participants defined menopause as a natural transition process that one should go through. Cleanliness, maturity, comfort of not having a period and positive changes in health behaviour were the concepts positively attributed to menopause, whereas hot flushes, getting old and difficulties in relationships were the negatives. Osteoporosis was an important concern for most of the participants. To deal with the symptoms, the non-pharmacological options were mostly favoured. Conclusion To our knowledge, this is the first qualitative study which focuses on Turkish women's menopausal experiences. Menopause was thought to be a natural process which was characterised by positive and negative features. Understanding these features and their implications in these women's lives may assist healthcare workers in helping their clients with menopause.

  15. Selection of the Optimal Herbal Compositions of Red Clover and Pomegranate According to Their Protective Effect against Climacteric Symptoms in Ovariectomized Mice

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    Su Jin Kang

    2016-07-01

    Full Text Available This study aimed to ascertain the optimal range of red clover dry extracts (RC and dried pomegranate concentrate powder (PCP to induce anti-climacteric effects. Thus, the dose ranges showing protective effect of mixed formulae consisting of RC and PCP were examined in ovariectomized mice. At 28 days after bilateral ovariectomy (OVX, mixed herbal compositions (RC:PCP = 1:1, 1:2, 1:4, 1:8, 2:1, 4:1, and 8:1 were administered orally, at 120 mg/kg once daily for 84 days. We evaluated that RC and PCP mixture attenuate OVX-caused obesity, hyperlipidemia, hepatic steatosis, and osteoporosis. Compared to OVX-induced control mice, body weight and abdominal fat weight in OVX-induced mice were significantly decreased, concomitantly with increase of uterus weight by RC:PCP mixture. Additionally, significant increases in serum estradiol levels were observed in all RC:PCP-treated mice. RC:PCP mixture also showed protective effect against OVX-induced hyperlipidemia, hepatic steatosis. Total body and femur mean bone mineral density (BMD, osteocalcin, bALP contents were effectively increased by RC:PCP mixture. Taken together, RC:PCP mixture (2:1, 1:1, and 4:1 has remarkable protective effects against the changes induced by OVX. In particular, RC:PCP mixture (2:1 shows the strongest effect and may be considered as a potential protective agent against climacteric symptoms.

  16. A pre-experimental study to evaluate the effectiveness of back massage among pregnant women in first stage of labour pains admitted in labour room of a selected hospital, Ludhiana, Punjab, India

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    Deepika Sethi

    2016-12-01

    Full Text Available Background: Labour is a health state that most women aspire to, at some point in their lives. The first thought that comes to the mind of an expecting woman regarding her delivery is the pain of labour. The major role and responsibility of the nurse is in identifying the problems of the woman in labour, providing appropriate information regarding the alternative modalities of pain relief during labour. A pre-experimental study was conducted to evaluate the effectiveness of back massage on pain among pregnant women in first stage of labour pains in a selected Hospital, Ludhiana, Punjab. The objectives of the study were to assess the pre-test level of pain in first stage of labour pains among pregnant women, to administer the back massage in first stage of labour pains, to assess the post-test level of pain and to compare the pre-test and post-test level of pain in first stage of labour pains among pregnant women and to determine the relationship of pre-test and post-test level of pain with the selected variables. Methods: Conceptual framework was based on General system theory by Ludwig Von Bertanlanffy. Modified Labour Pain Relief Tool and Participants Opinionnarie were used to assess the effectiveness of back massage. Results: Findings of the study were in the pre-test mean score was 5.83 and post-test mean score was 3.75 which was found statistically highly significant at p<0.01 level. Gravida had significant impact on level of pain. Back massage had impact on level of pain among pregnant women. Conclusions: Present study revealed that in the pre-test mean score was 5.83 and post-test mean score was 3.75 which was found statistically highly significant at p<0.01 level. Age, education, mother’s occupation, period of gestation and any history of abortion had no significant relationship with pain, and gravida had statistically significant relationship with pain. Back massage had impact on pain level. Therefore it was concluded that back massage

  17. [Leanness, obesity, and breast cancer risk-different impact of body weight on breast cancer risk according to women's life stages].

    Science.gov (United States)

    Suzuki, Reiko; Saji, Shigehira

    2015-05-01

    Numerous epidemiological studies, although not all, in Western countries have reported a possible differential impact of BMI on breast cancer risk in women of various lifestages. Among premenopausal women, a number of epidemiological studies in Western populations suggested a weak inverse association between BMI and breast cancer risk. Conversely, there exists substantial evidence for a statistically significant positive association between body weight and breast cancer risk among postmenopausal women. The cumulative exposure to estrogen throughout a woman's life is one of the significant risk factors for breast cancer. After menopause, adipose tissue is a major source of estrogen. Therefore, an increase in body fat after menopause is one of the possible explanations for the positive association of body weight with the development of breast cancer. To evaluate the impact of body weight on the risk of breast cancer, we need to consider the role of adipose tissue in the development and differentiation of normal mammary glands. Special attention should be paid to women in their twenties and/or during their lactation periods when the development of normal mammary glands is significant. Further studies are needed to investigate the association between BMI and breast cancer risk, considering the role of body fat in the development of mammary glands.

  18. Decreasing menopausal symptoms in women undertaking a web-based multi-modal lifestyle intervention: The Women's Wellness Program.

    Science.gov (United States)

    Anderson, Debra; Seib, Charrlotte; McGuire, Amanda; Porter-Steele, Janine

    2015-05-01

    Menopausal transition can be challenging for many women. This study tested the effectiveness of an intervention delivered in different modes in decreasing menopausal symptoms in midlife women. The Women's Wellness Program (WWP) intervention was delivered to 225 Australian women aged between 40 and 65 years through three modes (i.e., on-line independent, face-to-face with nurse consultations, and on-line with virtual nurse consultations). All women in the study were provided with a 12-week Program Book outlining healthy lifestyle behaviors while women in the consultation groups were supported by a registered nurse who provide tailored health education and assisted with individual goal setting for exercise, healthy eating, smoking and alcohol consumption. Pre- and post-intervention data were collected on menopausal symptoms (Greene Climacteric Scale), health related quality of life (SF12), and modifiable lifestyle factors. Linear mixed-effect models showed an average 0.87 and 1.23 point reduction in anxiety (plifestyle intervention embedded within a wellness framework has the potential to reduce menopausal symptoms and improve quality of life in midlife women thus potentially enhancing health and well-being in women as they age. Of course, study replication is needed to confirm the intervention effects.

  19. Las ciencias sociales como discurso de la salud reproductiva. El ejemplo del climaterio femenino The social sciences as discourse in reproductive health. The example of female climacteric

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    Fernando Lolas Stepke

    1998-01-01

    Full Text Available Tomando como ejemplo la construcción del climaterio femenino por parte de la medicina, de la opinión profana y de las ciencias sociales, se examinan los modelos de interrelación entre estos discursos y se propone la tesis de que la aportación de las ciencias sociales consiste en una reformulación de la base cognitiva de las profesiones de la salud en un nivel de integración.Climacteric is constructed by medicine, lay knowledge, and the social sciences. This article examines the interrational models involving these different discourses and proposes that the contribution of the social sciences lies in a reformulation of the cognitive base of the health professions at an integrative level.

  20. Oral contraception for women of middle age.

    Science.gov (United States)

    Ruan, Xiangyan; Mueck, Alfred O

    2015-11-01

    Women at middle age have decreased fertility and their pregnancies are higher risk. Combined oral contraceptives (COC) are effective but confer increased risk of age-related diseases, especially cardiovascular diseases. These risks are lower, however, with progestogen-only pills (POP). Therefore, other than the levonorgestrel intrauterine device (LNG-IUD), POP are usually the first choice, even though they do often lead to bleeding problems, which are already frequent in the perimenopause. However, the main risk of COC, venous thromboembolism, seems not to be relevant in (non-hospitalized) Chinese women and perhaps also other Asian women. COC may therefore be in fact a better choice than POP for these groups. In contrast to POP and IUDs, they have a variety of benefits especially important for middle-aged women, including a large decrease of the risk of ovarian, endometrial and colorectal cancer, an improvement in bleeding irregularities, a reduction of climacteric symptoms and some protection against bone loss. Further research is needed into individualized and safe contraception that takes into account ethnicity, as well as other factors.

  1. Markers of iron status are associated with stage of pregnancy and acute-phase response, but not with parity among pregnant women in Guinea-Bissau

    DEFF Research Database (Denmark)

    Kæstel, Pernille; Aaby, Peter; Ritz, Christian;

    2015-01-01

    While prenatal Fe supplementation prevents maternal Fe deficiency and anaemia, it is uncertain whether it improves infant health outcomes, at least when taken by Fe-replete women. Inflammation as well as physiological changes complicates the assessment of Fe status during pregnancy. In the present...... pregnancy. Using cut-off values for Fe deficiency as established in non-pregnant individuals, 52 % of the women had sTfR levels >2·3 mg/l, while only 25 % had serum ferritin levels 2·3 mg/l decreased to 47 % after adjustment for elevated serum CRP and ACT levels. On the contrary, the proportion of serum...... ferritin pregnancy-specific cut-offs since increased erythropoiesis is expected in response to increased plasma volume of pregnancy. The present study further underlines the need to adjust...

  2. Telbivudine treatment of hepatitis B virus-infected pregnant women at different gestational stages for the prevention of mother-to-child transmission

    Science.gov (United States)

    Tan, Zhangmin; Yin, Yuzhu; Zhou, Jin; Wu, Lingling; Xu, Chengfang; Hou, Hongying

    2016-01-01

    Abstract This prospective study evaluated the viability of telbivudine for blocking mother-to-child transmission (MTCT) of hepatitis B virus (HBV) infection. Pregnant women positive for the hepatitis B surface antigen began telbivudine treatment before 14 weeks of gestation (i.e., early), between 14 and 28 weeks of gestation (late), or not at all (control). In the late-treatment group, 55 women terminated telbivudine therapy within puerperium. All neonates underwent routine hepatitis B immunoglobulin plus vaccination. Mothers and infants were followed for 7 months after birth. Pregnancy outcomes were similar among the 3 groups. HBV MTCT rates in the early and late treatment and control groups were 0, 0, and 4.69%, respectively. The rates of infant vaccination success among the 3 groups were similar, as were neonatal outcomes including birth weights, asphyxia, hyperbilirubinemia, Apgar score, birth defects, and weight and height at 7 months. Puerperal discontinuation of telbivudine did not increase the alanine transaminase value at 7 months after birth, but increased serum HBV DNA levels, and rates of positive hepatitis Be-antigen. Telbivudine treatment in HBV-infected pregnant women was associated with lower serum HBV DNA levels and reduced rates of HBV MTCT; there were no associated changes in pregnancy or neonatal outcomes at birth or 7 months after birth, or in the rate of infant vaccination success. Puerperal drug withdrawal after short-term antiviral therapy will not influence hepatic function, but may increase virus replication. PMID:27749537

  3. Protocol for a pre-implementation and post-implementation study on shared decision-making in the surgical treatment of women with early-stage breast cancer

    NARCIS (Netherlands)

    Savelberg, W.; Moser, A.; Smidt, M.; Boersma, L.; Haekens, C.; Weijden, T. van der

    2015-01-01

    BACKGROUND: The majority of patients diagnosed with early-stage breast cancer are in a position to choose between having a mastectomy or lumpectomy with radiation therapy (breast-conserving therapy). Since the long-term survival rates for mastectomy and for lumpectomy with radiation therapy are comp

  4. Markers of iron status are associated with stage of pregnancy and acute-phase response, but not with parity among pregnant women in Guinea-Bissau.

    Science.gov (United States)

    Kæstel, Pernille; Aaby, Peter; Ritz, Christian; Friis, Henrik

    2015-10-14

    While prenatal Fe supplementation prevents maternal Fe deficiency and anaemia, it is uncertain whether it improves infant health outcomes, at least when taken by Fe-replete women. Inflammation as well as physiological changes complicates the assessment of Fe status during pregnancy. In the present study, we measured the concentrations of serum ferritin and soluble transferrin receptors (sTfR), Hb and the acute-phase proteins C-reactive protein (CRP) and α1-antichymotrypsin (ACT) in a cross-sectional study among 738 pregnant women attending antenatal care in Guinea-Bissau, West Africa. Multiple linear regression analysis was used to identify the predictors of Fe status markers. The mean gestational age was 23 (sd 7) weeks. Serum ferritin values were lower with progressing gestation, from 27% lower during weeks 16-20 of gestation up to 59% lower after 29 weeks of gestation compared with early pregnancy. Using cut-off values for Fe deficiency as established in non-pregnant individuals, 52% of the women had sTfR levels >2·3 mg/l, while only 25% had serum ferritin levels 2·3 mg/l decreased to 47% after adjustment for elevated serum CRP and ACT levels. On the contrary, the proportion of serum ferritin < 12 μg/l increased to 33% after adjustment for ACT and CRP. The high proportion of elevated serum sTfR calls for pregnancy-specific cut-offs since increased erythropoiesis is expected in response to increased plasma volume of pregnancy. The present study further underlines the need to adjust for inflammation when serum sTfR and serum ferritin are used to assess Fe status in pregnancy.

  5. Estadiamento inicial dos casos de câncer de mama e colo do útero em mulheres brasileiras Initial staging of breast and cervical cancer in Brazilian women

    Directory of Open Access Journals (Sweden)

    Luiz Claudio Santos Thuler

    2005-11-01

    nas regiões onde estes hospitais estão localizados houve melhora na detecção precoce destes tipos de câncer.PURPOSE: to analyze time trends in the clinical staging at the moment of diagnosis in patients with breast and cervix cancer based on data produced by the Brazilian Public Health System (SUS. METHODS: in the first part of this study we identified the published documents describing clinical staging of patients at the moment of diagnosis. Considering their scarcity and poor representativity we conducted the second part of this study through an active search for information. A form was sent via regular mail to all cancer centers in the country (n=173 requesting information about the tumor site and stage at diagnosis by year, in the period of 1995-2002. The statistical analysis was performed using the "R" statistical package. The results are reported as percentage and boxplots. RESULTS: in the first part of the study (1990-1994 we described data from 18 hospitals concerning 7,458 patients with breast cancer and 7,216 patients with cervix cancer. The median of the percentage of cancers diagnosed at an advanced stage (stages III or IV was 52.6 and 56.8%, respectively. In the second part of the study (1995-2002 data were collected from 89 cancer hospitals and 7 chemotherapy or radiotherapy clinics. There was a total of 43,442 cases of breast cancer and 29,263 of cervix cancer. The response rate based on the potential contact list was 55%. The median percentage of patients in advanced stage was 45.3% for breast cancer and 42.5% for cervix cancer. CONCLUSIONS: few studies have examined the time trends in staging of cancer at diagnosis in Brazilian hospitals. Data obtained from Hospital Cancer Registries showed that in the last decade there was a reduction in the percentage of cervix and breast cancer at the advanced stage. This reduction can be due to an improvement in early detection of these cancers.

  6. Randomized Control Trial: Evaluating Aluminum-Based Antiperspirant Use, Axilla Skin Toxicity, and Reported Quality of Life in Women Receiving External Beam Radiotherapy for Treatment of Stage 0, I, and II Breast Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Watson, Linda C., E-mail: Linda.watson@albertahealthservices.ca [Department of Interdisciplinary Practice, Community Oncology, Alberta Health Services-Cancer Care, Calgary, AB (Canada); Gies, Donna [Department of Radiation Oncology Nursing, Tom Baker Cancer Centre, Alberta Health Services-Cancer Care, Calgary, AB (Canada); Thompson, Emmanuel [Department of Mathematics and Statistics, University of Calgary Faculty of Science, Calgary, AB (Canada); Thomas, Bejoy [Department of Psychosocial Resources, Tom Baker Cancer Centre, Alberta Health Services-Cancer Care, Calgary, AB (Canada); Department of Psychosocial Oncology, University of Calgary Faculty of Medicine, Calgary, AB (Canada)

    2012-05-01

    Purpose: Standard skin care instructions regarding the use of antiperspirants during radiotherapy to the breast varies across North America. Women have articulated that when instructed to not use antiperspirant, the potential for body odor is distressing. Historical practices and individual opinions have often guided practice in this field. The present study had 2 purposes. To evaluate whether the use of aluminum-based antiperspirant while receiving external beam radiotherapy for stage 0, I, or II breast cancer will increase axilla skin toxicity and to evaluate whether the use of antiperspirant during external beam radiotherapy improves quality of life. Methods: A total of 198 participants were randomized to either the experimental group (antiperspirant) or control group (standard care-wash only). The skin reactions in both groups were measured weekly and 2 weeks after treatment using the National Cancer Institute Common Toxicity Criteria Adverse Events, version 3, toxicity grading criteria. Both groups completed the Functional Assessment for Chronic Illness Therapy's questionnaire for the breast population quality of life assessment tool, with additional questions evaluating the effect of underarm antiperspirant use on quality of life before treatment, immediately after treatment, and 2 weeks after treatment during the study. Results: The skin reaction data were analyzed using the generalized estimating equation. No statistically significant difference was seen in the skin reaction between the 2 groups over time. The quality of life data also revealed no statistically significant difference between the 2 groups over time. Conclusions: Data analysis indicates that using antiperspirant routinely during external beam radiotherapy for Stage 0, I, or II breast cancer does not affect the intensity of the skin reaction or the self-reported quality of life. This evidence supports that in this particular population, there is no purpose to restrict these women from

  7. 重庆地区妊娠妇女早中孕期叶酸水平分析%Analysis of folic acid levels in early and medium stage of pregnant women in Chongqing area

    Institute of Scientific and Technical Information of China (English)

    何敏; 向林

    2014-01-01

    Objective To understand the serum folic acid level in early and medium stage of pregnant women in Chongqing area .Methods The chemiluminescence method was adopted to detect serum folic acid levels in 3 312 cases of pregnant women .Results The serum folic acid level in the early pregnancy group was higher than that of the medium pregnancy group ,and the folic acid deficiency rate was lower than that in the medium pregnancy group ,the difference was statistically significant (P<0 .05);as the gestational age increase ,the serum folic acid level was in-creased and the folic acid deficiency rate was decreased with statistical difference (P< 0 .05) .Conclusion Pregnant women replenishing folic acid and monitoring the level of folic acid have the important significance to prepotency .%目的:了解重庆地区妊娠妇女早中孕期血清叶酸水平。方法采用化学发光法对3312例孕妇血清叶酸水平进行检测。结果早孕组血清叶酸水平高于中孕组,叶酸缺乏率低于中孕组,差异有统计学意义(P<0.05);随孕龄增加,血清叶酸水平增加,叶酸缺乏率降低,差异有统计学意义(P<0.05)。结论妊娠妇女做好叶酸补充,监测孕妇体内叶酸水平对于优生优育具有重要意义。

  8. Qualidade do sono em mulheres paulistanas no climatério Quality of sleep of climacteric women in São Paulo: some significant aspects

    OpenAIRE

    Carmen Lúcia Souza; José Mendes Aldrighi; Geraldo Lorenzi Filho

    2005-01-01

    OBJETIVO: O climatério é um período de grandes transformações em que a qualidade do sono usualmente se deteriora. O objetivo foi avaliar subjetivamente a qualidade do sono em mulheres no climatério (35 a 65 anos). MÉTODOS: Um questionário contendo informações pessoais, hábitos/saúde, sexualidade e sono foi aplicado a 271 mulheres. RESULTADOS: A amostra estudada constituiu-se principalmente de mulheres casadas, ativas profissionalmente, de alta condição econômica e escolaridade, não usuárias d...

  9. Caracterização da qualidade de vida segundo o estado menopausal entre mulheres da Região Sul do Brasil Characterization of the quality of life by menopausal status among women in the South region of Brazil

    Directory of Open Access Journals (Sweden)

    Dino Roberto Soares De Lorenzi

    2009-12-01

    Full Text Available OBJETIVOS: caracterizar a qualidade de vida de mulheres climatéricas residentes na Região Sul segundo o estado menopausal delas. MÉTODOS: foram entrevistadas 236 mulheres com idades entre 40 e 65 anos, durante feira de saúde realizada em cidade do Sul do Brasil, em março de 2005. Na avaliação da qualidade de vida, utilizou-se a versão brasileira do instrumento Menopause Rating Scale. RESULTADOS: das entrevistadas, 133 eram pré-menopáusicas e 103 pós-menopáusicas. As primeiras referiram sintomas climatéricos moderados e severos em 37,6% e 24,0%, respectivamente, enquanto as mulheres pós-menopáusicas, relataram sintomas moderados e severos em 36,9% e 39,4% dos casos, respectivamente. Os escores globais de qualidade de vida não mostraram diferenças entre os grupos estudados (p=0,12, ainda que o grupo pré-menopáusico tenha referido mais sintomas psicológicos (p=0,05 e o pós-menopáusico mais sintomas somato-vegetativos (pOBJECTIVES: to characterize the quality of life of climacteric women residing in the South region by menopausal status. METHODS: two hundred and thirty-six women aged between 40 and 65 were interviewed during a health fair held in March 2005 in a city in the South of Brazil. Their quality of life was assessed using the Brazilian version of the Menopause Rating Scale. RESULTS: of those interviewed, 133 were pre-menopausal and 103 post-menopausal. Moderate and severe climacteric symptoms were reported by 37.6% and 24.0% of the former, respectively, while 36.9% and 39.4% of the post-menopausal women reported moderate and severe symptoms, respectively. There were no differences between the two groups studied in terms of overall scores on the quality of life scale (p=0.12, although the pre-menopausal group reported more psychological symptoms (p=0.05 and the post-menopausal group more somatic-vegetative (p<0.01 and urinogenital (p=0.01 symptoms. CONCLUSIONS: quality of life was not influenced by menopausal status

  10. 流产对再次妊娠分娩产程及胎盘异常的影响%Effect of induced aborion on stage of labor and placental abnormality of primiparous women during parturition

    Institute of Scientific and Technical Information of China (English)

    王志强; 杨希娟

    2010-01-01

    目的 探讨人工流产后对未生育妇女再次妊娠产程及胎盘异常的影响.方法 对176例妊娠有人工流产史74例(观察组)和无人工流产史102例(对照组)的初产妇进行回顾性调查,分析其产程、胎盘异常的发生情况.结果 观察组产妇的第三产程时间(10.75±2.64)min长于对照组(8.12±3.26)min,差异有统计学意义(P<0.05).观察组胎盘粘连、胎盘残留、低置胎盘的发生率分别为13.52%、10.81%、8.11%,明显高于对照组2.95%、1.96%、0.98%,差异有统计学意义(P<0.05).观察组胎盘置入率(2.71%)高于对照组(0.98%),但差异无统计学意义(P>0.05).结论 人工流产可使未生育妇女妊娠分娩第三产程延长并增加胎盘异常的发生率,应尽可能杜绝产前人工流产.%Objective To investigate the effect of induced aborion on stage of labor and placental abnormality of primiparous women during parturition. Methods Birth process and abnormal placenta during labor for 74 women with a history of induced abortion (observation group) and 102 women without a history of induced abortion ( control group) in their first parities were collected and compared. Results The third stage of labor of the observation group was (10.75 ±2.64) min,longer than (8.12 ±3.26)min of the control group,the difference had statistical significance(P <0.05). The rate of placenta adhesion,placental remnants and low lying placenta of the observation group were 13.52%, 10.81% and 8.11% respectively, significantly higher than 2.95 %, 1.96% and 0.98% in the control group(P <0. 05). Conclusion It was demonstrated that induced aborion had obvious untoward effect on pregnancy such as prolonged third stage of labor and increased incidence of placental abnormalities. So, it was necessary to prevent induced aborion for primiparous women.

  11. Thyroid Cancer Staging

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ja Young; Kim, Soo Jin; Kim, Eun Kyung; Kwak, Jin Young [Yonsei University College of Medicine, Seoul (Korea, Republic of)

    2011-06-15

    The current prevalence of thyroid cancer in women is high. Likewise, other cancers and thyroid cancer have been based on the TNM classification system. Staging of thyroid cancer has an important role in determining the extent of surgical excision and lymph node dissection, planning the adjuvant therapy after surgery and predicting the recurrence rate and the prognosis of patients. Ultrasonography is the basic imaging modality to identify the tumor size and the extent of lymph node metastasis. More recently, computed tomography, magnetic resonance imaging and positron emission tomography provide additional help for the staging of thyroid cancer. So, this article describes the 7th edition of the TNM staging of thyroid cancer, as proposed by the American Joint Committee on Cancer, and the details of radiologic evaluation of the T, N and M stages

  12. Vietnamese women at solidarity meeting of world women in Cuba.

    Science.gov (United States)

    1998-01-01

    This article summarizes experiences of a Vietnamese delegation at a solidarity meeting of world women during April 13-16, 1998, in Cuba. The President of the Viet Nam Women's Union headed the delegation. The advisor was the vice-chairperson of the Vietnamese National Assembly. The delegation participated in 6 forums: women and sustainable economic development; women, health, education, and social security; women, communication and the mass media; women in politics and decision-making; women, violence and discrimination; and national independence, sovereignty, peace, and women. The delegation also participated in sessions on women's issues; implementation issues; women parliamentarians; and migrant and displaced women. The delegation met with delegates from other countries and participated in a world meeting and an Asian-Pacific meeting to support Cuban women. The entire delegation presented a stage show of songs, which was well received by the 3000 participants. The delegation met with Cuban delegates to discuss the formation of women's groups and to build better relations between the women of both countries. The delegation visited a training center of women cadres and the center for gender education. Participants adopted the Havana Declaration, which states the intention of world women to eradicate poverty and war and to promote peace, progress, and happiness in all countries. The Havana Declaration condemned the US embargo against Cuba. Fidel Castro spoke and expressed gratitude for the strong support from world women, especially Vietnamese women.

  13. S-adenosyl-L-methionine usage during climacteric ripening of tomato in relation to ethylene and polyamine biosynthesis and transmethylation capacity.

    Science.gov (United States)

    Van de Poel, Bram; Bulens, Inge; Oppermann, Yasmin; Hertog, Marten L A T M; Nicolai, Bart M; Sauter, Margret; Geeraerd, Annemie H

    2013-06-01

    S-adenosyl-L-methionine (SAM) is the major methyl donor in cells and it is also used for the biosynthesis of polyamines and the plant hormone ethylene. During climacteric ripening of tomato (Solanum lycopersicum 'Bonaparte'), ethylene production rises considerably which makes it an ideal object to study SAM involvement. We examined in ripening fruit how a 1-MCP treatment affects SAM usage by the three major SAM-associated pathways. The 1-MCP treatment inhibited autocatalytic ethylene production but did not affect SAM levels. We also observed that 1-(malonylamino)cyclopropane-1-carboxylic acid formation during ripening is ethylene dependent. SAM decarboxylase expression was also found to be upregulated by ethylene. Nonetheless polyamine content was higher in 1-MCP-treated fruit. This leads to the conclusion that the ethylene and polyamine pathway can operate simultaneously. We also observed a higher methylation capacity in 1-MCP-treated fruit. During fruit ripening substantial methylation reactions occur which are gradually inhibited by the methylation product S-adenosyl-L-homocysteine (SAH). SAH accumulation is caused by a drop in adenosine kinase expression, which is not observed in 1-MCP-treated fruit. We can conclude that tomato fruit possesses the capability to simultaneously consume SAM during ripening to ensure a high rate of ethylene and polyamine production and transmethylation reactions. SAM usage during ripening requires a complex cellular regulation mechanism in order to control SAM levels.

  14. Well staged

    Energy Technology Data Exchange (ETDEWEB)

    Budd, Godfrey

    2011-06-15

    Packers Plus Energy Services Inc. has commercially launched QuickFRAC, a multi-stage completition system which can fracture four to five isolated stages in one treatment and set up a record of 23-stage slickwater frac in less than 10 hours. It could take up to 40 days to do 100 fracture treatments with other systems. This technology makes it possible to distribute fluid at each port thanks to the limited entry system. In order to make multiple isolated stages within one treatment zone, each zone includes multiple QuickPORT sleeves with packers on either side. The other technology which made this possible is the repeater port system, it allows them to perform more frac stages. This technology could be useful in the future since the need for stages will be doubling soon with microdarcy shale oil extraction which is more difficult than gas.

  15. Analysis on Mental Health of Women at Different Stages of Pregnancy and its Relationship with Personality Traits%不同孕期孕妇心理健康状况及与个性的相关性调查

    Institute of Scientific and Technical Information of China (English)

    张金云; 郭晓燕

    2011-01-01

    目的 探讨不同妊娠期孕妇的心理健康状况及其与个性特征的关系.方法 分别对179例不同妊娠期孕妇进行调查分析,采用90项症状清单(SCL-90)评估心理健康状况和采用艾森克人格问卷(EPQ)测定孕妇的个性特征.结果 ①妊娠组焦虑因子分明显高于对照组(t=2.246,P=0.033),其余因子分比较差异均无统计学意义;②孕早期孕妇精神病性因子分较孕中期和孕晚孕妇高(F=4.116,P=0.029),其余因子分比较差异均无统计学意义.艾森克人格N 因子分与精神病性因子呈正相关(r-0.208,P=0.022).结论 妊娠期孕妇存在心理健康问题,主要是焦虑情绪,孕早期孕妇的精神病性倾向较高,与孕妇的个性特征有关.应做好孕期的心理保健工作,孕早期孕妇注意矫正个性缺陷,有助于孕期的心理健康.%Objective To explore the mental health status of women at different stages of pregnancy and its relationship with personality traits. Methods One hundred and seventy nine pregnant women were enrolled in this survey. Symptom Checklist 90 (SCL-90) and Eysenck Personality Questionnaire (EPQ) were used to assess the mental health and personality, respectively. Resuits ①The score of anxiety factor in the pregnant women group was higher than that of the control group ( t = 2. 246, P = 0. 033). ②The score of psychotic factor in the early gestation group was higher than that of mid-gestation and late gestation groups (F = 4.116, P = 0.029 ) ;the level of ' N' factor of EPQ was positive correlated with the score of psychotic factor of SCL90( r = 0.208, P = 0. 022 ). Conclusion The mental health problems of pregnant women were mainly the anxiety. Pregnant women tended to suffer psychotic problems during early gestation,and this is related with personality traits. The self mental care during pregnancy ,especially the correction of personality disorder in the early gestation, should contribute to the improvement of mental health.

  16. Trading stages

    DEFF Research Database (Denmark)

    Steiner, Uli; Tuljapurkar, Shripad; Coulson, Tim

    2012-01-01

    Interest in stage-and age structured models has recently increased because they can describe quantitative traits such as size that are left out of age-only demography. Available methods for the analysis of effects of vital rates on lifespan in stage-structured models have not been widely applied ...... examples. Much of our approach relies on trading of time and mortality risk in one stage for time and risk in others. Our approach contributes to the new framework of the study of age- and stage-structured biodemography....

  17. Women's Health

    Science.gov (United States)

    Women have unique health issues. And some of the health issues that affect both men and women can affect women differently. Unique issues ... and men also have many of the same health problems. But these problems can affect women differently. ...

  18. Health of Indonesian women city-dwellers of perimenopausal age.

    Science.gov (United States)

    Samil, R S; Wishnuwardhani, S D

    1994-10-01

    In the last few years more women of climacteric age, living in urban areas, have been seeking medical care. In 1989, on the invitation of 6 women's organizations in Jakarta and other cities, the Indonesian Menopause Society gave talks and held discussions in cooperation with the Department of Obstetrics and Gynaecology, Faculty of Medicine of the University of Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta. These occasions were used to accumulate data from women participants of 40 years of age and older. The age of the respondents ranged between 40-59 years. Most were 42 years old (13.9%). Ninety-four percent were still married. Twenty-five percent had three living children. Sixty-three percent of the respondents were high school graduates who worked full time (33%), part time, or were unemployed. The average menarche age was 13 and menopausal age 50-51. Menopausal complaints were rare, hence medical consultations were rare. Tranquilizers were prescribed for those who did seek medical help. This data constitutes the basis of the formulation of a strategy to solve menopause related problems in Indonesia, where female life expectancy, and the contribution of women to society, is on the increase.

  19. Determinants of Menopausal Symptoms among Ghanaian Women

    Directory of Open Access Journals (Sweden)

    Jacob Setorglo

    2012-07-01

    Full Text Available The onset of menopause is unique to every woman with varying symptoms which have implications on health and well-being. This study evaluated the perception, knowledge and beliefs about menopause and the prevalence of climacteric symptoms. The study was a cross-sectional survey of 280 menopausal women aged 45 years and older in the Accra Metropolis of the Greater Accra Region of Ghana. Data on socio-demographic characteristics, knowledge, beliefs and experience of menopausal symptoms were collected using a semi-structured questionnaire. Anthropometric data on weight, height, % body fat and MUAC were also taken. All data were analyzed using SPSS version 16.0 and presented as means and frequencies. Predictors of menopausal symptoms were determined by logistic regression. The mean age of onset of menopause was (48±2.9 years with 98.2% having some knowledge of the signs and symptoms of menopause. The most frequently reported menopausal symptoms by the women were: night sweats (83.2%, hot flashes (76.4%, mood swings (72.5% and vaginal dryness (71.4%. The significant predictors for the occurrence of the most common symptoms reported were: age at onset of menstruation, age of start of menopause, body weight and % body fat. There was a decreased risk of experiencing symptoms such as night sweats, mood swings and vaginal dryness as age at menopause increased. Menopausal transition was determined by both vasomotor and urogenital symptoms. Counseling and support are needed to enable women manage the symptoms better. Most women have heard of and know what menopause is.

  20. 坤泰胶囊与戊酸雌二醇对更年期综合征各种症状的不同疗效分析%Effects of Kuntai Capsule and Estradiol Valerate on Different Symptoms of Climacteric Syndrome

    Institute of Scientific and Technical Information of China (English)

    陈蓉; 林守清; 杨欣; 栾艳秋; 陈继英; 李冬梅

    2013-01-01

    目的 分析中成药坤泰胶囊与西药戊酸雌二醇(E2V)对更年期综合征各种症状的不同疗效.方法 选择2002年4月至2003年8月在北京协和医院和北京大学第一临床医院就诊的更年期综合征患者147例,进行随机、双盲、双模拟平行对照研究3个月,将每日潮热3次以上的更年期妇女随机分为坤泰组(坤泰胶囊4粒,每日3次,77例)和E2V组(协坤片0.5 mg,每晚1次,70例),按照停经时间再分为绝经过渡期和绝经后两亚组.研究期间患者记录症状日记,随访时由专人进行改良Kupperman症状(K)评分评估更年期症状.结果 ①治疗3个月时,坤泰组和E2V组K评分较治疗前均有统计学意义(P<0.05).坤泰组、E2V组K评分临床有效率分别为86.2%、78.9%,两组比较差异无统计学意义(P>0.05).坤泰过渡期组、绝经后组K评分临床有效率分别为96.5%、77.7%,两组比较差异有统计学意义(P<0.05).②两种药物对不同停经时间亚组患者的潮热评分疗效比较差异无统计学意义(P>0.05).随治疗时间延长,两组的各种症状治疗有效率均明显提高.除头晕、阴道干涩外,两种药物对K评分中其余10项症状的疗效均无统计学意义(P>0.05).过渡期组患者感觉异常、忧郁、头晕、疲乏、肌肉关节痛、头痛6项症状,在治疗1周和1个月时坤泰组疗效优于E2V组.结论 坤泰胶囊和E2V对改善更年期综合征症状均有效.坤泰胶囊对过渡期患者的疲乏、头痛等症状疗效优于小剂量E2V,而对绝经后患者的阴道干涩疗效后者优于前者.%Objective To analyze the different effects of Kuntai capsule,a traditional Chinese preparation and estradiol valerate on different symptoms of climacteric syndrome.Methods One hundred and forty-seven perimenopausal women with hot flushes more than 3 times a day from Peking Union Medical College Hospital and the First Hospital Affiliated to Peking University from Apr.2002 to Aug.2003

  1. A measurement-specific quality-of-life satisfaction during premenopause, perimenopause and postmenopause in Arabian Qatari women

    Directory of Open Access Journals (Sweden)

    Abdulbari Bener

    2014-01-01

    Full Text Available Objective: The aim of this study was to use an instrument, the menopause-specific quality-of-life satisfaction in the state of Qatar for the premenopausal, menopause and postmenopausal period.Design: A cross-sectional descriptive study was used to generate menopause symptoms experienced by Arabian Gulf women. Measurement-specific quality-of-life satisfaction questionnaires and face-to-face interviews were performed.Setting: Primary Health Care (PHC Centers in Qatar.Materials and Methods: A multistage sampling design was used and a representative sample of 1,500 women aged 40-60 years were included during July 2012 and November 2013, and 1,158 women agreed to participate (77.2% and responded to the study.Results: The mean age and standard deviation of the subjects was 50.9 ± 6.1. The median age of natural menopause in the present study was 49 years [mean and standard deviation 49.9 ± 2.7]. The rate of consanguineous marriages in the sample was found to be 30.3%. There were statistically significance differences between menopausal stages with regard to ethnicity, education level, occupation, type of housing condition, and consanguinity. There were statistically significance differences between menopausal stages concerning BMI groups, Systolic BP, Diastolic BP, physical activity, parity, and sheesha smoking habits. Meanwhile, the present study revealed that the most common disease was found to be diabetes mellitus (11.4%, followed by hypertension (6.6%, asthma (5.6% and CHD (2.5%, and the majority of subjects (69.5% had no specific disease. The most frequent symptom was "aches in the back and neck" (49.2%, night sweat (37.2%, low backache (35.7%, feeling nervous (35.4% followed by "aches in the muscles/joints" (34.6%, hot flashes (33.3%, decreased social activities (28.3%, decreased leisure activities (47.6%, difficulty sleeping (28.9%, mood swings (25.4%, and decreased concentration (28.3%, sexual activity (24.1% and total energy level (26

  2. Freqüência da atividade sexual em mulheres menopausadas Factors related to frequency of sexual activity of postmenopausal women

    Directory of Open Access Journals (Sweden)

    Dino Roberto Soares De Lorenzi

    2006-08-01

    Full Text Available OBJETIVO: Identificar os fatores relacionados à freqüência da atividade sexual entre mulheres pós-menopáusicas. MÉTODOS: Estudo transversal de 206 mulheres pós-menopáusicas entre 45 e 60 anos atendidas em um serviço universitário da região Sul do Brasil entre junho e outubro de 2002. A atividade sexual foi avaliada pelo número de relações sexuais no último mês e a sintomatologia climatérica pelo Índice de Kupperman. Na análise estatística, fez-se regressão linear múltipla. RESULTADOS: Das mulheres pesquisadas, 176 (85% eram sexualmente ativas. Cerca de 60,6% relataram diminuição da atividade sexual após a menopausa, o que atribuíram principalmente à impotência sexual do parceiro (41,7%. Aproximadamente 25,7% negaram satisfação com o intercurso sexual. Na análise por regressão linear múltipla, associaram-se à atividade sexual a idade (pOBJECTIVE: To identify factors related to the frequency of sexual activity of postmenopausal women METHODS: A cross-section study of 206 postmenopausal women between 45 and 60 years of age was made at a university health care service in the South of Brazil between June and October 2002. Evaluations were made of sexual activity according to the number of sexual intercourses in the previous month and the climacteric symptoms using the Kupperman index. Statistical analysis was performed with multiple linear regression analysis. RESULTS: Of those surveyed 176 (85% women were sexually active. Although 60.6% reported a decrease in sexual activity after menopause, mostly attributing it to the husband's sexual impotence (41.7%. Approximately 25.7% stated they had no satisfaction with sexual intercourse. By means of multiple linear regression analysis the following aspects were associated to sexual activity: age (p<0.1, degree of sexual satisfaction (p=0.01, and climacteric symptomatology (p=0.02. As age increased the climacteric symptoms were more intense and sexual activity was less

  3. O olhar dos responsáveis pela política de saúde da mulher climatérica La mirada de los responsables por la política de la salud de la mujer climatérica The look of the responsible ones for the politics of health of woman climacterics

    Directory of Open Access Journals (Sweden)

    Queli Lisiane Castro Pereira

    2009-06-01

    Regional Co-ordination's Health of Rio Grande do Sul, in the perspective of the Responsible ones for the politics of woman's health. The search of climacterics was characterized for being in function of the symptoms and typical complaints of this phase and, doubts how much to a possible gestation. It has necessary looking for practices the constitutional law of the completeness, preserving the rights already conquered by the women and to extend the attendants services, so that they can correspond in such a way quantitative as qualitatively to the demands, to the necessities of promotion, prevention and recovery of the health of the users of the brazilian system of health.

  4. Safety of zoledronic acid and incidence of osteonecrosis of the jaw (ONJ) during adjuvant therapy in a randomised phase III trial (AZURE: BIG 01-04) for women with stage II/III breast cancer.

    Science.gov (United States)

    Coleman, R; Woodward, E; Brown, J; Cameron, D; Bell, R; Dodwell, D; Keane, M; Gil, M; Davies, C; Burkinshaw, R; Houston, S J; Grieve, R J; Barrett-Lee, P J; Thorpe, H

    2011-06-01

    The AZURE trial is an ongoing phase III, academic, multi-centre, randomised trial designed to evaluate the role of zoledronic acid (ZOL) in the adjuvant therapy of women with stage II/III breast cancer. Here, we report the safety and tolerability profile of ZOL in this setting. Eligible patients received (neo)adjuvant chemotherapy and/or endocrine therapy and were randomised to receive neither additional treatment nor intravenous ZOL 4 mg. ZOL was administered after each chemotherapy cycle to exploit potential sequence-dependent synergy. ZOL was continued for 60 months post-randomisation (six doses in the first 6 months, eight doses in the following 24 months and five doses in the final 30 months). Serious (SAE) and non-serious adverse event (AE) data generated during the first 36 months on study were analysed for the safety population. 3,360 patients were recruited to the AZURE trial. The safety population comprised 3,340 patients (ZOL 1,665; control 1,675). The addition of ZOL to standard treatment did not significantly impact on chemotherapy delivery. SAE were similar in both treatment arms. No significant safety differences were seen apart from the occurrence of osteonecrosis of the jaw (ONJ) in the ZOL group (11 confirmed cases; 0.7%; 95% confidence interval 0.3-1.1%). ZOL in the adjuvant setting is well tolerated, and can be safely administered in addition to adjuvant therapy including chemotherapy. The adverse events were consistent with the known safety profile of ZOL, with a low incidence of ONJ.

  5. Staging atmospheres

    DEFF Research Database (Denmark)

    Bille, Mikkel; Bjerregaard, Peter; Sørensen, Tim Flohr

    2015-01-01

    The article introduces the special issue on staging atmospheres by surveying the philosophical, political and anthropological literature on atmosphere, and explores the relationship between atmosphere, material culture, subjectivity and affect. Atmosphere seems to occupy one of the classic...... localities of tensions between matter and the immaterial, the practical and the ideal, and subject and object. In the colloquial language there can, moreover, often seem to be something authentic or genuine about atmosphere, juxtaposing it to staging, which is implied to be something simulated or artificial....... This introduction seeks to outline how a number of scholars have addressed the relationship between staged atmospheres and experience, and thus highlight both the philosophical, social and political aspects of atmospheres...

  6. Experience of menopause in aboriginal women: a systematic review.

    Science.gov (United States)

    Chadha, N; Chadha, V; Ross, S; Sydora, B C

    2016-01-01

    Every woman experiences the menopause transition period in a very individual way. Menopause symptoms and management are greatly influenced by socioeconomic status in addition to genetic background and medical history. Because of their very unique cultural heritage and often holistic view of health and well-being, menopause symptoms and management might differ greatly in aboriginals compared to non-aboriginals. Our aim was to investigate the extent and scope of the current literature in describing the menopause experience of aboriginal women. Our systematic literature review included nine health-related databases using the keywords 'menopause' and 'climacteric symptoms' in combination with various keywords describing aboriginal populations. Data were collected from selected articles and descriptive analysis was applied. Twenty-eight relevant articles were included in our analysis. These articles represent data from 12 countries and aboriginal groups from at least eight distinctive geographical regions. Knowledge of menopause and symptom experience vary greatly among study groups. The average age of menopause onset appears earlier in most aboriginal groups, often attributed to malnutrition and a harsher lifestyle. This literature review highlights a need for further research of the menopause transition period among aboriginal women to fully explore understanding and treatment of menopause symptoms and ultimately advance an important dialogue about women's health care.

  7. 女性更年期抑郁症实施护理干预的效果评价%Evaluation of the effect of nursing intervention on female climacteric depression

    Institute of Scientific and Technical Information of China (English)

    张晶波

    2015-01-01

    Objective To explore the female menopause depression nursing intervention effect. Methods 50 cases offemale climacteric depression were selected in 2013, computers were randomly divided into control group and treatment group as a clinical research object, the control group of 25 cases of female climacteric depression wereonly given antidepressant drugs and general care treatment; 25 cases of female climacteric depression patients in the treatment group in the concurrent administration of antidepressant treatment increase the nursing interventiontherapy. Comparison between the treatment group and the control group of female climacteric depression inpatients with antidepressant treatment and different nursing method, self rating scale before and after treatmentthe scores in SDS depression, and analysis and discussion. Results The patients in the treatment group after drug treatment and nursing intervention, SDS self rating Depression Scale score relatively low, the treatment effect is better than that of control group. (P<0.05), the result of the data with statistical significance. Conclusion The curative effect of nursing intervention on antidepressants female climacteric depression patients, very good,not only make the depression psychological response in patients with ease, but also improve patients mental outlook, with improving effects on the patients with nervous system function, so that patients with endocrine systemfunction tends to be normal or even higher level, compared with the control group use nursing the traditional method, its advantage is obvious, it is worth in clinical application.%目的:探讨女性更年期抑郁症实施护理干预的效果。方法在2013年中选取女性更年期抑郁症患者50例,计算机随机分为对照组和治疗组作为临床研究对象,各25例。对照组中25例女性更年期抑郁症患者给予抗抑郁药物和一般的护理治疗;治疗组的25例女性更年期抑郁症患者则在给予抗抑

  8. Enforcing women's rights through law.

    Science.gov (United States)

    Cook, R J

    1995-06-01

    Because women have to be equal partners in development to insure its sustainability, the human rights of women must be foremost on development agendas. Ratification of and adherence to the Convention on the Elimination of All Forms of Discrimination Against Women (the Women's Convention) would be a powerful international tool in this regard. In various countries, progress towards legalizing rights for women is passing through a first stage which focusses on the protection of specific rights to a second stage in which sex is included as a prohibited ground of discrimination to a third stage which addresses the pervasive and structural nature of the violation of women's rights. It is expected that governments will renew their commitment to the Women's Convention at the Fourth World Conference on Women (WCW) and, thus, take more seriously their obligations to report progress and remove reservations. Regional initiatives, such as the Organization of American States' 1994 Convention on the Prevention, Punishment, and Eradication of Violence Against Women, can also be used to protect women's rights, and the application of national constitutions and domestic laws remains the first line of defence for women. Particular attention must be paid to laws which apply to property rights, nationality, equality within the family, reproductive and other health issues, and violence against women. The Draft Plan of Action prepared for the WCW challenges states to specify their plans to eliminate discrimination. While this Plan may prove to lack vision, women's nongovernmental organizations are playing a major role in accelerating the movement of international and domestic law towards justice for women.

  9. Staging Mobilities

    DEFF Research Database (Denmark)

    Jensen, Ole B.

    In recent years, the social sciences have taken a “mobilities turn.” There has been a developing realisation that mobilities do not “just happen.” Mobilities are carefully and meticulously designed, planned and staged (from above). However, they are equally importantly acted out, performed...... that mobility is more than movement between point A and B. It explores how the movement of people, goods, information, and signs influences human understandings of self, other and the built environment. Moving towards a new understanding of the relationship between movement, interaction and environments......, the book asks: what are the physical, social, technical, and cultural conditions to the staging of contemporary urban mobilities?...

  10. Biological and Social Factors Related to Women's Health during Climateric Factores biológicos y sociales relacionados con la salud de la mujer durante el climaterio

    Directory of Open Access Journals (Sweden)

    Elodia María Rivas Alpízar

    2011-12-01

    Full Text Available

    Background: the life of women, being extended to 30 years after menopause, undergoes an environmental impact that overlaps the clinical expression of the cessation of reproductive function. This increases the need to provide, at this stage, a comprehensive care. Objective: To identify some biological and social factors related to women's health during climateric. Methods: Descriptive and cross sectional study conducted in 307 women from 40 to 59 years old in the Area III Polyclinic of Cienfuegos, from January to December 2006. Through household interviews, a form that allowed collecting general, clinical and medical support information was filled. Results: 56.3% of women experienced mild climacteric syndrome, circulatory (77.2% and psychological (60% symptoms being the most referred ones. The average age of menopause onset was between 47 and 51 years old. It appeared earlier in smokers. The age of menarche, the number of pregnancies and births and menstrual patterns were not related to the age of menopause onset. 44% of women were hypertensive, 41.4% were pre-obese and 100% were sedentary. 81.8% of them did not seek for medical support. Hormonal therapy was prescribed for 32.1% of patients. Conclusions: Despite the risk factors and the chronic diseases that were detected, women interviewed did not seek for medical support, even when they presented discomfort to some extent. This was caused by the lack of information on this stage of life and the inexistence of specialized multidisciplinary consultations in Primary Health Care.

    Fundamento: la vida de la mujer, que se ha  extendido 30 años después de la menopausia, recibe un impacto del medio sobre la expresión clínica del cese de la función reproductiva, lo cual incrementa la necesidad de brindarles en esta etapa una atención integral. Objetivo: identificar

  11. 早期宫颈癌保留卵巢内分泌功能的临床研究%Clinical research on ovarian function in women with early stage cervical squamous carcinoma

    Institute of Scientific and Technical Information of China (English)

    郑丽萍; 段欣梅

    2013-01-01

    Objective: To investigate the factors of influencing the ovarian function in women with early stage cervical squamous carcinoma who underwent radical hysterectomy, pelvic lymphadenectomy and lateral ovarian transpostion ( LOT) .Methods: 27 patients with age less than 45 years old, lesions 0.05) .There were significant differences in FSH, LH, E2 and Kupperman score of 7 cases underwent LOT and radiotherapy before and after operation 6 months.The level of FSH, LH, Kupperman score in LOT and postopera-tion radiotherapy group were higher than those of no radiotherapy group ( P 0.05) .Conclusion: LOT is effective in retaining the ovary function of early stage cervical squamous carcinoma patients.Pelvic radiotherapy after LOT can greatly protect the ovary function, but it also partly damages the transposed ovarian.The patients more than 40 years old can also benefit from LOT.%目的:探讨早期宫颈鳞癌患者行宫颈癌根治术[原位保留双侧卵巢或行侧面卵巢移位术(LOT)]后对卵巢内分泌功能的影响.方法:选取年龄<45岁、病灶<2 cm、FIGO分期为IA2 ~ IBI、未发现区域淋巴结转移的27例宫颈鳞癌患者,其中手术时行LOT的23例,卵巢原位保留的4例,测定患者术前、术后的血清女性激素水平.结果:LOT后未放疗组16例患者术后6个月FSH、LH、E2水平及Kupperman评分与术前比较差异无统计学意义(P>0.05):LOT后放疗组7例患者术后6个月FSH、LH水平、Kupperman评分与术前比较差异有统计学意义(P<0.05);LOT后放疗组FSH、LH、Kupperman评分高于未放疗组(P<0.05),低于原位保留放疗组4例(P<0.05);LOT的手术年龄在40~ 45岁的9例患者中,卵巢功能正常3例,卵巢功能减退6例;< 40岁的患者14例中,卵巢功能正常10例,卵巢功能减退4例.两组均无卵巢功能丧失,两组间卵巢功能正常的比例无显著差异(P>0.05).结论:年轻宫颈鳞癌患者行宫颈癌手术并LOT时,术

  12. Prevalence of hormone replacement therapy in a sample of middle-aged women

    DEFF Research Database (Denmark)

    Pedersen, S H; Jeune, B

    1988-01-01

    A survey based on a postal questionnaire sent to a random sample of Danish women aged 40-59 yr living on the island of Fünen (n = 401, response rate = 79%) revealed that the overall prevalence of the use of hormone replacement therapy (HRT) was 16%, the highest rate being in the 50-54 age group (21......%). Among post-menopausal women the rate was 21% and it was highest of all (37%) in those who had undergone an artificial menopause. The median age at the start of treatment was 44.3 yr among the artificial menopause and 48.9 yr among the natural menopause subjects. About half of the women were treated...... with natural oestrogen alone and over a third with cyclic natural oestrogen in combination with progestogens. Almost one-third of the women had consulted their doctor about climacteric complaints and two-thirds of these were current or past users of HRT. The women had ambiguous feelings towards HRT...

  13. 更年期的妇女保健%Menopausal women health care

    Institute of Scientific and Technical Information of China (English)

    杜翠玲; 赵艳

    2014-01-01

    All the time,many people recognize the one-sided on female climacteric,and it brings great trouble to menopausal women.This paper starts from the psychological and physiological characteristics of menopausal women.It puts forward the necessity and importance of menopausal women health care,and provides practical guidance for menopausal women health care.It is conducive to the effective control and prevention of physical and mental disease in menopause women,and provides a good foundation for reducing blindness.%一直以来,很多人对女性更年期的认识存在片面性,给更年期女性带来很大的困扰。本文从更年期妇女的心理和生理特点分析入手,提出了更年期妇女保健的必要性和重要性,为更年期妇女保健提供了可行性指导,有利于更年期妇女有效地进行身心疾病防治,为减少认知盲目性打下良好的基础。

  14. Olfactory perception in women with physiologically altered hormonal status (during pregnancy and postmenopause

    Directory of Open Access Journals (Sweden)

    Savović Slobodan N.

    2002-01-01

    Full Text Available Introduction Olfaction is considered to be the ability to: perceive, conduct and recognize scents and odors. With its numerous connections to the limbic system and reticular formation, the olfactory system affects regulation of numerous vegetative functions, visceral functions and sexual behavior. Since estrogen and progesterone protect the olfactory function, changes in their levels in particular physiological states in women (in pregnancy and postmenopause exert an influence on the ability to feel and recognize smells. It has its role in creating emotions and adjustment of visceral and vegetative response to particular emotional states. Also, it represents the connection between higher cortical functions and the endocrine system. Material and methods Our investigation was performed at the Ear, Nose and Throat Clinic in Novi Sad. The research included 80 healthy women classified into 4 groups; 20 women aged between 20 and 30; 20 women in the first trimester of pregnancy aged between 20 and 30; 20 premenopausal women aged between 41 and 50; and 20 women at least 3 years in postmenopause, aged between 41 and 50. For our research we used an olfactometer and the Fortunato-Niccolini method. Results and discussion In pregnancy the thresholds of perception (TP and identification (TI of examined substances were slightly lower in comparison to nonpregnant women of the same ages, but without any statistical significance (p>0.05. In climacteric-postmenopausal women there was a significant decrease of olfactory ability in comparison to nonmenopausal women of the same ages (p<0.01. Conclusion All changes of the olfactory function in pregnancy are explained by mental changes of pregnant women as well as their hormonal status. Significant decrease of olfactory ability in postmenopause is explained by decline in sexual hormone levels.

  15. Avanços na elucidação dos mecanismos de ação de Cimicifuga racemosa (L. Nutt. nos sintomas do climatério Advances on the elucidation of mechanisms of action of Cimicifuga racemosa (L. Nutt. in climacteric symptoms

    Directory of Open Access Journals (Sweden)

    A.G. Silva

    2009-01-01

    Full Text Available O objetivo deste trabalho foi levantar os avanços ocorridos para a compreensão da atuação terapêutica de Cimicifuga racemosa, um fitoterápico utilizado no tratamento dos sintomas do climatério em mulheres nas quais a terapia de reposição hormonal (TRH é contra-indicada. A revisão bibliográfica possibilitou concluir que existem quatro principais hipóteses para esclarecer a base mecanística de ação: indução de apoptose por meio da ativação de caspases, inibição do ciclo celular em G1 por alteração de proteínas reguladoras, efeito central em receptor 5HT e ação estrogênica evidenciada pela inibição seletiva dos receptores nicotínicos da acetilcolina. Porém, é incipiente a produção científica abordando as bases moleculares que sustentem os referidos mecanismos de ação. Ainda há necessidade de elucidação quanto à possível existência de pelo menos mais um receptor estrogênico que possa ser o alvo de ligação para as substâncias ativas de C. racemosa, bem como avançar no conhecimento da atividade reguladora seletiva de receptores estrogênicos já evidenciada em estudos de farmacologia experimental.The aim of this survey was to assemble the advances in the comprehension of the therapeutic action of Cimicifuga racemosa, a phytotherapic drug used in the treatment of climacteric symptoms in women to whom the usual hormonal replacement therapy (HRT is counter-indicated. This literature review led to the conclusion that there are four main hypotheses to elucidate the mechanistic basis of action: apoptosis induction by means of caspase activation, cell cycle inhibition at G1 step through disturbance of regulatory proteins, central effect on 5HT receptors, and estrogenic action evidenced by selective inhibition of nicotinic acetylcholine receptors. However, scientific literature is still incipient in supporting the molecular bases for the previously proposed mechanisms of action. There is also the need to

  16. Aspectos clínicos e metabólicos de mulheres na pós-menopausa tratadas com tibolona Clinical and metabolic aspects of postmenopausal women treated with tibolone

    Directory of Open Access Journals (Sweden)

    Salim Wehba

    2000-02-01

    Full Text Available Objetivos: analisar a repercussão da tibolona sobre os sintomas do climatério e sobre algumas variáveis clínicas e metabólicas. Métodos: foram avaliadas 34 pacientes na pós-menopausa que foram submetidas ao tratamento com tibolona na dose de 2,5 mg/dia por 48 semanas. Foram analisados os seguintes parâmetros: peso, pressão arterial e perfis lipídico e lipoprotéico, representados pelos níveis de colesterol total, HDL-c, LDL-c, VLDL-c e triglicerídeos. Resultados: melhora relevante da sintomatologia do climatério foi demonstrada por decréscimo significativo do índice menopausal de Kupperman (pPurpose: to evaluate the effects of tibolone on climacteric symptoms and clinical and metabolic variables. Methods: thirty-four postmenopausal women were treated orally with 2.5 mg tibolone daily for 48 weeks and evaluated as to climacteric complaints, clinical aspects such as weight and blood pressure and lipid profile (total cholesterol, HDL-c, LDL-c, VLDL-c and triglycerides. Results: a significant improvement of climacteric complaints was demonstrated by a significant decrease in the Kupperman index (p<0.001 and the mean number of hot flushes (p<0.001 from the first month of treatment onwards. There was a significant decrease in total cholesterol, triglycerides and VLDL-c (p<0.001. The LDL-c levels presented a slight decrease (not significant. The HDL-c levels showed a significant decrease at week 24. However these levels returned to baseline levels at week 48. With regard to the vital signs no change in body weight and blood pressure was measured. The side effects were mild and temporary, vaginal bleeding, nausea and edema being the most common. Conclusion: tibolone may be considered a safe and efficient option to treat climacteric symptoms in postmenopausal women without significant impact on lipid profile.

  17. Profile of bazedoxifene/conjugated estrogens for the treatment of estrogen deficiency symptoms and osteoporosis in women at risk of fracture

    Directory of Open Access Journals (Sweden)

    Rossini M

    2013-07-01

    Full Text Available Maurizio Rossini,1 Stefano Lello,2 Ignazio Sblendorio,3 Ombretta Viapiana,1 Elena Fracassi,1 Silvano Adami,1 Davide Gatti11Department of Medicine, Rheumatology Unit, University of Verona, Italy; 2Endocrinological Gynecology, Pathophysiology of Menopause and Osteoporosis, Dermopathic Institute of Immacolata, Roma, Italy; 3Medical Coach Italia Center, Bari, ItalyAbstract: Decreasing levels of estrogens during menopause are associated with reduced bone density and an increased risk of osteoporosis. Many women also experience bothersome vasomotor and vaginal symptoms during the menopausal transition. Results of systematic reviews and meta-analyses of randomized controlled trials have shown that both systemic estrogen therapy or hormone therapy (estrogen combined with a progestin are useful to prevent bone loss, and they are the most effective treatment for such climacteric symptoms as hot flushes, sweating, vaginal dryness, and dyspareunia. Unfortunately, estrogen therapy and hormone therapy increase the risk of endometrial and breast cancer, respectively. The selective estrogen receptor modulators (SERMs result in positive estrogenic effects on bone, with no negative effects on the endometrium and breast but do not provide relief from postmenopausal symptoms. The combination of a SERM with estrogen as a tissue selective estrogen complex (TSEC is a new strategy for the prevention of bone loss and the treatment of climacteric symptoms. This combination is particularly interesting from a clinical point of view, taking into account that estrogen alone did not increase breast cancer risk by the Women's Health Initiative. TSEC is hypothesized to provide the benefits of estrogen-alone therapy, with an improved tolerability profile because the SERM component can make possible the elimination of progestin. The objective of this review was to critically evaluate the evidence from the reports published to date on the use of bazedoxifene (a third

  18. Profile of bazedoxifene/conjugated estrogens for the treatment of estrogen deficiency symptoms and osteoporosis in women at risk of fracture.

    Science.gov (United States)

    Rossini, Maurizio; Lello, Stefano; Sblendorio, Ignazio; Viapiana, Ombretta; Fracassi, Elena; Adami, Silvano; Gatti, Davide

    2013-01-01

    Decreasing levels of estrogens during menopause are associated with reduced bone density and an increased risk of osteoporosis. Many women also experience bothersome vasomotor and vaginal symptoms during the menopausal transition. Results of systematic reviews and meta-analyses of randomized controlled trials have shown that both systemic estrogen therapy or hormone therapy (estrogen combined with a progestin) are useful to prevent bone loss, and they are the most effective treatment for such climacteric symptoms as hot flushes, sweating, vaginal dryness, and dyspareunia. Unfortunately, estrogen therapy and hormone therapy increase the risk of endometrial and breast cancer, respectively. The selective estrogen receptor modulators (SERMs) result in positive estrogenic effects on bone, with no negative effects on the endometrium and breast but do not provide relief from postmenopausal symptoms. The combination of a SERM with estrogen as a tissue selective estrogen complex (TSEC) is a new strategy for the prevention of bone loss and the treatment of climacteric symptoms. This combination is particularly interesting from a clinical point of view, taking into account that estrogen alone did not increase breast cancer risk by the Women's Health Initiative. TSEC is hypothesized to provide the benefits of estrogen-alone therapy, with an improved tolerability profile because the SERM component can make possible the elimination of progestin. The objective of this review was to critically evaluate the evidence from the reports published to date on the use of bazedoxifene (a third-generation SERM) in combination with conjugated estrogens in postmenopausal women. The conclusion is that effectively, the combination of bazedoxifene and conjugated estrogens may be a promising alternative to hormone therapy for the prevention of osteoporosis and the treatment of postmenopausal symptoms in non-hysterectomized postmenopausal women.

  19. Women boxers

    DEFF Research Database (Denmark)

    Gems, Gerald; Pfister, Gertrud Ursula

    2014-01-01

    This article fills a gap in the very limited literature on women's boxing by examining the gendered space in which women engaged in the sport as participants in saloons, vaudeville theatres and the prize ring. In doing so, they challenged the contemporary gender order and disputed the notion...... of women as the weak sex. Vaudeville provided women with an opportunity to present physical performances that surpassed the restrictions placed on women within the mainstream middle-class society. This article includes biographical sketches of some of the outstanding female boxers of the era by drawing...

  20. Survey on Knowledge, Attitude and Practice of Passive Smoking Among Non - smoking Pregnant Women in Early Gestational Stage%长沙市孕早期非吸烟孕妇被动吸烟KAP调查

    Institute of Scientific and Technical Information of China (English)

    周婧瑜; 胡劲松; 王进; 朱江

    2011-01-01

    Objective To investigate the condition of passive smoking, and the related knowledge, attitude and practice among non - smoking pregnant women in Changsha, and to provide the evidence for reducing passive smoking exposure of non-smoking pregnant women. Methods Six hundred and forty - one non - smoking pregnant women whose pregnant periods were < 12 - week were interviewed by questionnaires. The data were analyzed by SPSS 13.0 software. Results Most of the pregnant women were short of the knowledge about the exact diseases caused by passive smoking. Pregnant women had a lower opposed rate on smoking in repast and entertainment places towards hospitals, schools and other public places. On persuading people not to smoke around, pregnant women had different attitudes towards different people. Pregnant women had the highest expected value on persuading their husbands smoking around, followed by their parents, father and mother in law, and other intimate family members. Pregnant women had the lowest expected value on persuading their leaders and strangers smoking around (< 35%). Conclusions Passive smoking exposure is a very serious public health problem among pregnant women. Educations and trainings are needed to increase the awareness of passive smoking harm and the ability to persuade people to stop smoking around.%目的 了解长沙市非吸烟孕妇被动吸烟情况以及相关知识、态度和行为,为减少孕妇被动吸烟提供科学依据.方法 对641位孕龄不大于12周的非吸烟孕早期孕妇进行有关被动吸烟的问卷调查,SPSS13.0统计软件进行分析.结果 孕妇对被动吸烟具体可以导致的危害了解不足;对在餐厅、咖啡吧等餐饮娱乐场所吸烟的容忍度显著高于医院、中小学校、公交车等公共场所;对周围吸烟者进行劝阻时,对丈夫的预计成功率最高,其次为父母、公公婆婆等亲密家庭成员,对单位领导和公共场所吸烟的陌生人的

  1. Cognitive behavioral therapy and physical exercise for climacteric symptoms in breast cancer patients experiencing treatment-induced menopause: design of a multicenter trial

    Directory of Open Access Journals (Sweden)

    van Beurden Marc

    2009-06-01

    Full Text Available Abstract Background Premature menopause is a major concern of younger women undergoing adjuvant therapy for breast cancer. Hormone replacement therapy is contraindicated in women with a history of breast cancer. Non-hormonal medications show a range of bothersome side-effects. There is growing evidence that cognitive behavioral therapy (CBT and physical exercise can have a positive impact on symptoms in naturally occurring menopause. The objective of this study is to investigate the efficacy of these interventions among women with breast cancer experiencing treatment-induced menopause. Methods/design In a randomized, controlled, multicenter trial, we are evaluating the effectiveness of CBT/relaxation, of physical exercise and of these two program elements combined, in reducing menopausal symptoms, improving sexual functioning, reducing emotional distress, and in improving the health-related quality of life of younger breast cancer patients who experience treatment-induced menopause. 325 breast cancer patients (aged Discussion Cognitive behavioral therapy and physical exercise are potentially useful treatments among women with breast cancer undergoing treatment-induced, premature menopause. For these patients, hormonal and non-hormonal therapies are contraindicated or have a range of bothersome side-effects. Hence, research into these interventions is needed, before dissemination and implementation in the current health care system can take place. Trial registration The study is registered at the Netherlands Trial Register (NTR1165 and ClinicalTrials.gov (NCT00582244.

  2. Life Satisfaction across Four Stages of Adult Life.

    Science.gov (United States)

    Medley, Morris L.

    1980-01-01

    For men life satisfaction was related to age stage in a monotonic increasing fashion. Life satisfaction scores remained relatively constant across the age stages for women. Family life and standard of living were found to be significant determinants of life satisfaction, for both sexes at each stage of adulthood. (Author)

  3. Effect of Climacteric Syndrome Hormone Replacement Therapy Compliance Related Factors and Preventive Countermeasures%影响更年期综合征激素替代治疗依从性相关因素及预防对策

    Institute of Scientific and Technical Information of China (English)

    董小艳

    2015-01-01

    目的:探讨影响更年期综合征激素替代治疗依从性的相关因素及预防措施。方法:104例更年期综合征患者根据患者个体情况分别应用单纯雌激素补充、单纯孕激素补充和雌孕(雄)激素联系补充3种方式,分析104例更年期综合征临床资料,进行激素替代治疗依从性判断,比较两组不同依从性相关因素上的差异,并进行统计学分析。结果:104例患者激素替代治疗依从性好62例(59.62%),激素替代治疗依从性差42例(40.38%);单因素χ²检验文化程度、家庭支持、居住地、心理状态、经济收入、对激素替代治疗认知、激素替代治疗不良反应、医疗费用、就诊条件9个指标差异有统计学意义(P<0.05)。Logistic回归分析影响更年期综合征激素替代治疗依从性的相关因素,激素替代治疗认知偏差、激素替代治疗不良反应、不良心理状况、居住农村(OR=4.70、4.29、3.89、3.17)。结论:更年期综合征激素替代治疗过程中依从性较差,导致依从性差影响复杂,应实施针对性措施提高激素替代治疗依从性。%Objective: To investigate the effects of menopause syndrome hormone replacement therapy compliance related factors and preventive measures.Method: 104 patients with climacteric syndrome according to individual condition used only estrogen supplement, progesterone supplementation alone and female pregnancy (male) hormone ties complement in three ways, to analyze climacteric syndrome clinical data, hormone replacement therapy compliance judgment of 104 cases, differences of compliance related factors between the two groups.Result: 104 patients with hormone replacement therapy compliance in 62 cases (59.62%), hormone replacement therapy for treatment of 42 cases of poor compliance (40.38%); single factor χ² test culture degree, family support, place of residence, the psychological condition, economic income

  4. 度洛西汀联合替勃龙治疗女性更年期抑郁症的疗效观察%Efficacy analysis of duloxetine combinate with tibolone in the treatment of female climacteric depression

    Institute of Scientific and Technical Information of China (English)

    赵士贵

    2015-01-01

    目的:探讨度洛西汀联合替勃龙治疗女性更年期抑郁症的疗效和安全性。方法选择2011年9月-2013年9月我院精神科收治的女性更年期抑郁症患者70例,随机分为治疗组与对照组各35例。对照组予度洛西汀肠溶片,治疗组在对照组治疗基础上给予替勃龙片。治疗6周用 HAMD,HAMA,TESS 量表评定疗效和不良反应。结果治疗组显效率85.7%,总有效率94.3%明显高于对照组的65.7%及80.0%,差异有统计学意义( P <0.05)。治疗1、2、4、6周后2组 HAMD 及 HAMA 评分均较治疗前及上一计分段明显降低,且治疗组评分降低程度较对照组更为明显,差异均有统计学意义(P <0.05)。2组常见不良反应发生率比较差异无统计学意义(P >0.05),患者均能耐受或经对症治疗缓解,未对治疗产生影响。结论度洛西汀联合替勃龙治疗女性更年期抑郁症的疗效优于单用度洛西汀且耐受性好。值得临床推广应用。%Objective To discuss the efficacy and safety of duloxetine combinate with tibolone in the treatment of fe-male climacteric depression. Methods From September 2011 to September 2013,70 cases of female patients with climacteric depression were selected,and then randomly divided into treatment group and control group,each of 35 cases. The control group received duloxetine for treatment. The treatment group was added tibolone based on the control group. After treatment for 6 weeks,the efficacy and safety were evaluated with HAMD,HAMA and TESS scale. Results The effective rate and total effec-tive rate was 85. 7% ,94. 3% respectively in the treatment group,which was obviously higher than 65. 7% ,80% in control group,the differences were statistically significant(P 0. 05). The patients were all tolerated or relieved by symptomatic treatment. Conclusion The efficacy of duloxetine combinate with tibolone was better in the treatment of female climacteric depression than

  5. 中西医结合治疗更年期抑郁患者的临床疗效%Clinical Observation on Treatment of Patients with Climacteric Depression with Combination of TCM and Western Medicine

    Institute of Scientific and Technical Information of China (English)

    刘兴华

    2015-01-01

    Objective To investigate the clinical effect of combined treatment of traditional Chinese medicine and Western medicine in patients with climacteric depression.Methods Colected from January 2014 2010 and Dece- mber in our hospital of 53 cases with depression were colected.According to the random number table method were divided into treatment group of 27 cases and control group(26 cases),two groups of patients were given fluoxetine or paroxetine and antidepressants,treatment group adds the clothing made of Chinese medicine,to according to the groups of patients with alprazolam,compared two groups of patients with clinical curative effect.Results After 6 weeks of treatment,the patients in the treatment group the total efficiency was 92.6%,and was significantly higher than that of the control group of 80.8%,the difference was statisticaly significant(P<0.05).Conclusion The combination of Chinese traditional and Western treatment of climacteric depression,antidepressants can improve patient compliance and tolerability, efficacy significantly.%目的:探讨中西医结合治疗更年期抑郁患者的临床疗效。方法收集2010年1月至2014年12月医院就诊的53例更年期抑郁患者资料,按随机数字表法将患者分为试验组(27例)和对照组(26例),患者均给予氟西汀或帕罗西汀等抗抑郁药物,试验组患者加服自制中药,对照组患者加服阿普唑仑。比较两组患者的临床疗效。结果治疗6周后,试验组患者总有效率为92.6%,明显高于对照组的80.8%,差异有统计学意义(P<0.05)。结论中西结合治疗更年期抑郁症,能够提高患者对抗抑郁药物的依从性和耐受性,疗效明显。

  6. [Hypertension in women].

    Science.gov (United States)

    Tagle, Rodrigo; Tagle V, Rodrigo; Acevedo, Mónica; Valdés, Gloria

    2013-02-01

    The present review examines the types of hypertension that women may suffer throughout life, their physiopathological characteristics and management. In early life, the currently used low-dose oral contraceptives seldom cause hypertension. Pregnancy provokes preeclampsia, its main medical complication, secondary to inadequate transformation of the spiral arteries and the subsequent multisystem endothelial damage caused by deportation of placental factors and microparticles. Hypertension in preeclampsia is an epiphenomenon which needs to be controlled at levels that reduce maternal risk without impairing placental perfusion. The hemodynamic changes of pregnancy may unmask a hypertensive phenotype, may exacerbate a chronic hypertension, or may complicate hypertension secondary to lupus, renovascular lesions, and pheochromocytoma. On the other hand a primary aldosteronism may benefit from the effect of progesterone and present as a postpartum hypertension. A hypertensive pregnancy, especially preeclampsia, represents a risk for cardiac, vascular and renal disease in later life. Menopause may mimic a pheochromocytoma, and is associated to endothelial dysfunction and salt-sensitivity. Among women, non-pharmacological treatment should be forcefully advocated, except for sodium restriction during pregnancy. The blockade of the renin-angiotensin system should be avoided in women at risk of pregnancy; betablockers could be used with precautions during pregnancy; diuretics, ACE inhibitors and angiotensin receptor antagonists should not be used during breast feeding. Collateral effects of antihypertensives, such as hyponatremia, cough and edema are more common in women. Thus, hypertension in women should be managed according to the different life stages.

  7. Iyengar-Yoga Compared to Exercise as a Therapeutic Intervention during (Neoadjuvant Therapy in Women with Stage I–III Breast Cancer: Health-Related Quality of Life, Mindfulness, Spirituality, Life Satisfaction, and Cancer-Related Fatigue

    Directory of Open Access Journals (Sweden)

    Désirée Lötzke

    2016-01-01

    Full Text Available This study aims to test the effects of yoga on health-related quality of life, life satisfaction, cancer-related fatigue, mindfulness, and spirituality compared to conventional therapeutic exercises during (neoadjuvant cytotoxic and endocrine therapy in women with breast cancer. In a randomized controlled trial 92 women with breast cancer undergoing oncological treatment were randomly enrolled for a yoga intervention (YI (n=45 or for a physical exercise intervention (PEI (n=47. Measurements were obtained before (t0 and after the intervention (t1 as well as 3 months after finishing intervention (t2 using standardized questionnaires. Life satisfaction and fatigue improved under PEI (p<0.05 but not under YI (t0 to t2. Regarding quality of life (EORTC QLQ-C30 a direct effect (t0 to t1; p<0.001 of YI was found on role and emotional functioning, while under PEI only emotional functioning improved. Significant improvements (p<0.001 were observed at both t1 and t2 also for symptom scales in both groups: dyspnea, appetite loss, constipation, and diarrhea. There was no significant difference between therapies for none of the analyzed variables neither for t1 nor for t2. During chemotherapy, yoga was not seen as more helpful than conventional therapeutic exercises. This does not argue against its use in the recovery phase.

  8. 武汉市城区育龄妇女孕前和孕早期增补叶酸情况调查与分析%Investigation and analysis on the supplementary situation of folic acid in women of child - bearing age before pregnancy and at early stage of pregnancy in urban areas of Wuhan city

    Institute of Scientific and Technical Information of China (English)

    黄俊; 王姽; 汪静

    2011-01-01

    Objective: To understand the supplementary situation of folic acid in women of child - bearing age before pregnancy and at early stage of pregnancy in urban areas of Wuhan city for prevention of neural tube malformation, explore the effect factors of supplement of folic acid preliminarily, and try to put forward corresponding solutions.Methods: 1 700 pregnant women who lived in urban areas of Wuhan city and went to perinatal health care outpatient department of the hospital from October 2009 to September 2010 were investigated by random sampling, 1 654 effective questionnaires were obtained.Results: The total supplement rate of folie acid in women of child -bearing age before pregnancy and at early stage of pregnancy in urban areas of Wuhan city was 86.58%, and 30.96% of the women of child - bearing age supplemented folic acid before pregnancy.The supplementary situation of folic acid in women older than 35 years was better, the women with high educational level knew more about the prevention knowledge of birth defects using supplementary folic acid, and the supplementary situation of folic acid was better.The proportion of the prevention knowledge of birth defects using supplementary folic acid from relatives and friends was the highest, the proportion from marriage registration center was the lowest.Conclusion: Strengthening the publicity of prevention knowledge of birth defects using supplementary folic acid is helpful to increase the rate of supplement of folic acid.Marriage registration center should strengthen the publicity of such knowledge to women, especially before their pregnancy.%目的:了解武汉市城区育龄妇女孕前和孕早期增补叶酸预防神经管畸形的情况,初步探讨影响增补叶酸的因素,尝试提出相应的解决办法.方法:通过随机抽样调查2009年10月~2010年9月在江岸区妇幼保健院围产保健门诊就诊的居住在武汉市城区的孕妇1 700人,其中有效调查问卷1 654例.结果:武汉

  9. Women and Politics – The Glass Ceiling

    OpenAIRE

    Irina Zamfirache

    2010-01-01

    The role of women in modern politics is a subject that needs further insight, considering the growthin number of women that nowadays have relevant political positions on the international stage.There are studies today that emphasize the equality issue and all that is gender role related, but ourinterest is to analyze the women representation in power related positions. Due to the fastmodernization of the political environment and the rapid spreading of the feminist way of thought,several auth...

  10. 自然分娩产妇产程与心理、生理及社会支持的相关性研究%Study on correlation between stages of labor and psychological, physiological, and social supports for parturient women adopting spontaneous labor

    Institute of Scientific and Technical Information of China (English)

    张宠英

    2012-01-01

    Objective: To explore the effects of psychological, physiological, and social supports on stages of labor during spontaneous labor. Methods: One hundred and two parturient women who demanded to adopt spontaneous labor and went to the hospital from January to October in 2011 underwent intervention consisting of psychological, physiological, and household supports during prenatal period and intrapartum period; 102 parturient women who demanded to adopt spontaneous labor during the same period were selected as control group, then the women underwent conventional nursing. The degrees of pain during stages of labor, duration times of labor, delivery modes, and the amounts of postpartum hemorrhage in the two groups were observed. Results: The rates of spontaneous labor and cesarean section in observation group were 76.47% (78/102) and 23.33% (24/102) , respectively; the rates of spontaneous labor and cesarean section in control group were 55. 88% (57/102) and 44. 12% (45/102), respectively, there was significant difference between the two groups (P<0.05); 60 parturient women (58. 82% ) in observation group were found with degree of pain ≤ Ⅰ during the first stage of labor, while 30 parturient women (29. 41% ) in control group were found with degree of pain ≤ Ⅰ during the first stage of labor, there was significant difference between the two groups (P < 0.05 ) ; compared with control group, the amount of postpartum hemorrhage in observation group decreased significantly. Conclusion: Psychological, physiological, and household supports and nursing intervention during stages of labor among the parturient women adopting spontaneous labor can reduce the amount of postpartum hemorrhage, relieve the degree of pain during stages of labor, shorten stages of labor, reduce cesarean section rate, and promote spontaneous labor effectively.%目的:探讨心理、生理以及社会支持等因素对自然分娩产程的影响.方法:对平湖市第二人民医院2011年1~10

  11. Cervical Cancer Stage IVA

    Science.gov (United States)

    ... historical Searches are case-insensitive Cervical Cancer Stage IVA Add to My Pictures View /Download : Small: 756x576 ... Large: 3150x2400 View Download Title: Cervical Cancer Stage IVA Description: Stage IVA cervical cancer; drawing and inset ...

  12. Women and Diabetes

    Medline Plus

    Full Text Available ... Information by Audience For Women Women's Health Topics Women and Diabetes Share Tweet Linkedin Pin it More ... women during pregnancy. Diabetes and Pregnancy (CDC) Diverse Women in Clinical Trials Campaign Clinical trials can help ...

  13. Women and Diabetes

    Science.gov (United States)

    ... Information by Audience For Women Women's Health Topics Women and Diabetes Share Tweet Linkedin Pin it More ... women during pregnancy. Diabetes and Pregnancy (CDC) Diverse Women in Clinical Trials Campaign Clinical trials can help ...

  14. Women's health

    Science.gov (United States)

    ... use at a later date Egg donation Sperm banking BLADDER CARE SERVICES The women's health services team ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

  15. Tu Women

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    When honored guests visit, Tu women will block the door and invite them to show their respect by drinking three cups of wine. Only after this ritual can the guests be led indoors and shown to their seats.

  16. Climateric: fatigue or third stage of the general adaptation syndrome Climaterio: fatiga o tercera etapa del síndrome de adaptación general

    Directory of Open Access Journals (Sweden)

    William Alvarez Gaviria

    2004-09-01

    Full Text Available The origin of climacteric has been subject of debate. Most opinions agree in that it arises exclusively from natural selection. In this paper the author argues that, besides this reason there is another, even more important; for him, climacteric is the final response to fatigue or the third stage of the general adaptation syndrome, just as in elderly people there is a loss of the capacity of proliferation of fibroblasts and lack of response to insulin. From a genetic point of view, this corresponds to an antagonic pleiotropy: the genetic program that has made the human adrenergic and corticotropic systems hyperactive, has also caused that they do not reach senescence intact. High concentrations of stress hormones during youth and adulthood in humans, as compared to chimpanzees, gorillas and orangutans, and the hormonal cascade reactions elicited by them are meaningfully related to our most conspicuous illnesses, our genotype/phenotype and, in the long term, with climacteric. Se ha conjeturado a menudo sobre las razones del climaterio y la mayoría de los autores sostiene que es un fenómeno que surge exclusivamente de la selección natural. Aquí asumimos que, aunque esa sea parte de la explicación, no es la razón primordial. Así como con la edad se da la pérdida, por ejemplo, de la capacidad proliferativa de los fibroblastos y de la sensibilidad a la insulina, el climaterio podría corresponder no más que a la fatiga o tercera etapa del Síndrome de Adaptación General. En un enfoque genético correspondería, pues, a una pleiotropía antagónica: el programa genético que ha hecho hiperactivos a los sistemas adrenérgico y corticotrópico del ser humano, evitaría también que llegara incólume al punto final de senescencia. Las altas concentraciones de hormonas de estrés en la juventud y la edad adulta que distinguen a nuestra especie, comparada con el chimpancé, el gorila y el orangután, y las reacciones hormonales en cascada que

  17. Women Words

    Institute of Scientific and Technical Information of China (English)

    Yuan Yuan

    2012-01-01

    Jiangyong County,a remote place in central China's Hunan Province,has been gathering more attention due to a strange-looking language passed down exclusively by women for hundreds of years. The language,which is called nushu,or women's script,is said to originate from Chinese square-block characters,but the orthography and pronunciation are quite different from all other branches of Chinese dialects.

  18. Leibniz's women.

    Science.gov (United States)

    Fara, Patricia

    2004-12-01

    Enlightenment natural philosophers were linked to one another in an extended correspondence network, but the female participants in this international Republic of Letters are rarely mentioned. Gottfried Leibniz relied on several such women not only for financial patronage, but also for intellectual stimulation. Although this hardworking and underpaid librarian at the Hanoverian Court is now one of the world's most famous mathematical philosophers, the women on whom he depended for ideas as well as support have been largely forgotten.

  19. 中国14家医院妇科门诊40~60岁患者绝经相关特征的调查%Survey on characteristics of menopause of Chinese women with the age of 40-60 years at gynecological clinic from 14 hospitals

    Institute of Scientific and Technical Information of China (English)

    陈蓉; 郁琦; 徐克惠; 谢梅青; 雷小敏; 任慕兰; 阮祥燕; 丁岩; 符书馨

    2013-01-01

    Objective To investigate the characteristics of menopause of Chinese women with the age of 40-60 years concerning gynecologic clinics in China.Methods From Mar.2008 to Sept.2008,a face-to-face questionnaire was conducted in gynecological clinic in perimenopausal and postmenopausal women in 14 hospitals in China,which included general demographic data,menstrual change process,climacteric symptoms and knowledge about menopause.Modified Kupperman index were used to evaluate climacteric symptoms during the recent week and awareness of hormonal replacement therapy were studied.Results A total of 1641 women were investigated.The ages of onset of menopause transition,climacteric symptoms and natural menopause were (47±4),(46±4),(49±3) years old respectively.Climacteric symptoms could be found in 78.43% (1287/1641) women during menopausal transition,which were mainly mild to moderate symptoms.The top 5 symptoms were fatigue and weakness (71.48%,1173/1641),irritability (68.68%,1127/1641),insomnia (67.65%,1110/1641),muscle and joint pain (64.11%,1052/1641) and hot flush (57.90%,950/1641).The climacteric symptoms were not constant during menopausal transition,usually more severe in late transition and postmenopausal periods,during which the moderate and severe symptoms were 59.1% (189/320) and 51.1% (291/570) respectively.Although most symptoms primarily appeared along with menstruation change,there are about 17.5% (172/981) patients experienced climacteric symptoms before menstruation change occurrence.There were 56.39% (733/1300)women had ever heard (mostly from gynecologist) about hormone replacement therapy from Obstetrician and Gynecologist.Conclusions Most of the women during menopausal transition had climacteric symptoms,usually mild and moderate ones.Although most symptoms primarily appeared along with menstruation change,there are other patients' experienced climacteric symptoms before menstruation change occurrence.%目的

  20. The c.1460C>T Polymorphism of MAO-A Is Associated with the Risk of Depression in Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    R. Słopień

    2012-01-01

    Full Text Available Objective. The aim of the study was an evaluation of possible relationships between polymorphisms of serotoninergic system genes and the risk of depression in postmenopausal women. Methods. We studied 332 women admitted to our department because of climacteric symptoms. The study group included 113 women with a diagnosis of depressive disorder according to the Hamilton rating scale for depression; the controls consisted of 219 women without depression. Serum 17β-estradiol concentrations were evaluated using radioimmunoassay, while polymorphisms in serotoninergic system genes: serotonin receptors 2A (HTR2A, 1B (HTR1B, and 2C (HTR2C; tryptophan hydroxylase 1 (TPH1 and 2 (TPH2, and monoamine oxidase A (MAO-A were evaluated using polymerase chain reaction-restriction. Results. We found that the 1460T allele of MAO-A c.1460C>T (SNP 1137070 appeared with a significantly higher frequency in depressed female patients than in the control group (P=0.011 and the combined c.1460CT + TT genotypes were associated with a higher risk of depression (P=0.0198. Patients with the 1460TT genotype had a significantly higher 17β-estradiol concentration than patients with the 1460CT genotype (P=0.0065 and 1460CC genotype (P=0.0018. Conclusions. We concluded that depression in postmenopausal women is closely related to the genetic contribution of MAO-A.

  1. Family, Religion, and Work among Arab American Women

    Science.gov (United States)

    Ghazal Read, Jen'nan

    2004-01-01

    Using data from a national survey of 501 Arab American women, this study examines the extent to which family behavior mediates the influence of religion on women's labor force activity. Prior research on families has largely overlooked the role of religion in influencing women's labor force decisions, particularly at different stages of the life…

  2. Between Stage and Screen

    NARCIS (Netherlands)

    Tornqvist, Egil

    1996-01-01

    Ingmar Bergman is worldwide known as a film and stage director. Yet no-one has attempted to compare his stage and screen activities. In Between stage and screen Egil Tornqvist examines formal and thematical correspondences and differences between a number of Bergman's stage, screen, and radio produc

  3. Autocuidado de mujeres en etapa de menopausia en Toluca, Mexico Autocuidado de mulheres na etapa da menopausa em Toluca, México Self care of women in the menopause stage in Toluca, Mexico

    Directory of Open Access Journals (Sweden)

    María Dolores Martínez Garduño

    2008-03-01

    úde.The woman in the menopause is exposed to risk factors that increase with the self-care. The objective was to identify self care practices in the menopause. Quantitative study, exploratory, with a sample of simple random probability, using the EPI INFO 2000, with 95% trust limit, 5% maximum error, in 354 women. Was observed a self-care deficit, mostly in alimentary habits, showing overweight and obesity (27%; the noise it is a factor that interfere in the sleep, the average sleep was about 5 to 7 hours; 40% don’t do physical exercise; 17.9% don’t do the uterine cervical cancer examination; 37.7% don’t do the breast self exam, without social security. 52.3% only go to the doctor when is ill. The frequent manifestations in the climatery are irregular bleeding, suffocation, fatigue and lack of libido. There aren’t enough information in this group of women, being the nurse who must assume the function of health educator.

  4. 合理情绪疗法治疗更年期皮肤瘙痒症46例%Rational-emotive behavior therapy for women with climacteric itching

    Institute of Scientific and Technical Information of China (English)

    尹洁; 向群英; 赖蓉

    2006-01-01

    目的观察合理情绪治疗法联合皿治林治疗更年期皮肤瘙痒症的疗效.方法对46例更年期皮肤瘙痒症病人分别采用合理情绪治疗法+皿治林(治疗组)和单独使用皿治林治疗(对照组)4周,治疗前后采用症状自评量表(SCL-90)评定疗效,临床症状判断有效率.结果治疗组4周后SCL-90评分总分及因子分显著降低,临床显效率治疗组52.17%,对照组17.39%,两组比较,差异有统计学意义(x2=6.13,P=0.013).结论合理情绪治疗法联合皿治林治疗更年期皮肤瘙痒症,有较好的治疗作用.

  5. Relação cálcio/proteína da dieta de mulheres no climatério Calcium/protein relation of women on the climacteric

    OpenAIRE

    Regina das Neves Girão Montilla; José Mendes Aldrighi; Maria de Fátima Nunes Marucci

    2004-01-01

    OBJETIVO: Avaliar a relação cálcio/proteína da dieta de mulheres no climatério. MÉTODOS: Em estudo transversal, foi avaliada a dieta de 154 mulheres entre 35 e 65 anos de idade, atendidas no Ambulatório de Saúde da Mulher Climatérica do Centro de Saúde-Escola da Faculdade de Saúde Pública da Universidade de São Paulo. Para obtenção do consumo alimentar de cálcio e de proteína, foi realizado inquérito alimentar pelo método ''recordatório de 24 horas''. A avaliação da relação cálcio/proteína fo...

  6. Study on State of Spirit and Body of Women in Climacteric Period by Yoga.%瑜伽锻炼对改善更年期女性心身状态的研究

    Institute of Scientific and Technical Information of China (English)

    赵阿勐; 刘海燕

    2011-01-01

    目的 探讨瑜伽锻炼对更年期女性心身状态的影响.方法 选取64名自愿参加瑜伽锻炼的更年期女性,通过16周规范的运动处方训练后,评估其心身状态的改变,同时选取64名具有相似背景的更年期女性进行对照研究.结果 训练组成员在焦虑水平、睡眠品质上有明显改善,与对照组比较有显著差异(t=0.46,0.17;P<0.05),训练组成员在心率、收缩压、舒张压、台阶指数、肺活量都得到明显的改善,与对照组相比差异具有统计学意义(t=0.11,0.24,0.52,0.19,0.71;P<0.05或P<0.01).结论瑜伽锻炼可以有效改善和提升更年期女性的心身状态.

  7. Women's Rights Unit.

    Science.gov (United States)

    Weiss, Helen; Weigel, Margaret

    Designed for use in the intermediate grades, this interdisciplinary unit helps students examine traditional and modern roles of women. Fourteen lessons focus on women's activities in colonial America, reasons for women's discontent, the women's rights movement of the 1800's, changes in the roles of women, enfranchisement of women, women's role…

  8. 围绝经期综合征与神经递质(5-羟色胺)相关性的临床研究进展%Climacteric Syndrome and Neurotransmitters(5-HT)Correlation of Clinical Research

    Institute of Scientific and Technical Information of China (English)

    李贺琦

    2011-01-01

    Objectives: To investigate the current domestic and international the serum of 5 - hydroxytryptamine (5 -HT) and climacteric syndrome clinical relevance of the mechanism and role of estrogen therapy relationship, and traditional Chinese medicine on the 5 - HT effects experimental study. Methods: A search at home and abroad in recent years the use of TCM treatment of perimenopausal syndrome, and with 5 - HT related clinical research. Results: Menopausal Patients 5 - HT abnormalities of reheat and sweating, insomnia and other symptoms by estrogen or Chinese medicine treatment of perimenopausal symptoms improved. Conclusion: Estrogen and traditional Chinese medicine on patients with perimenopausal syndrome of 5 - HT was significant regulatory role.%目的:探讨目前国内外有关血清5-羟色胺(5-HT)与围绝经期综合征临床症状的相关性的机制,及其与雌激素治疗的关系,和中医中药对5-羟色胺影响的动物实验研究.方法:检索近几年来国内外运用中西医疗法治疗围绝经期综合征,及其与5-羟色胺相关性的临床研究成果.结果:围绝经期患者血清5-羟色胺水平异常,出现烘热汗出,失眠等临床症状,经雌激素或中医中药治疗,围绝经期症状得到改善.结论:雌激素及中医中药对围绝经期综合征患者血清5-羟色胺水平有显著性调节作用.

  9. Revisiting Erikson's Views on Women's Generativity, or Erikson Didn't Understand Midlife Women.

    Science.gov (United States)

    Edelstein, Linda N.

    The past 15 years have brought a re-evaluation of women's adult development in light feminist thinking. However, many outdated assumptions in psychological theory remain comfortably ensconced; to challenge these ideas, some misrepresentations of women's experience are examined. The focus is on Erik Erikson's explanation of the second stage of…

  10. Prognostic features of surgical stage I uterine carcinosarcoma.

    Science.gov (United States)

    Ferguson, Sarah E; Tornos, Carmen; Hummer, Amanda; Barakat, Richard R; Soslow, Robert A

    2007-11-01

    Uterine carcinosarcomas (CSs) are aggressive neoplasms, with 5-year overall survival (OS) rates of less than 35%. They are customarily separated into types harboring either heterologous or homologous mesenchymal elements, but the prognostic significance of this finding is controversial. Our goal was to study clinicopathologic features of possible prognostic relevance in surgical stage I uterine CS. A retrospective clinical and histopathologic review was performed for all women diagnosed with surgical stage I uterine CS. These tumors were compared with stage I high-grade endometrial (HGEm) carcinomas for clinical outcomes. There were 42 cases of surgical stage I uterine CS identified between January 1990 and January 2004. The disease-free survival and OS rates for patients with stage I CS were significantly worse compared with stage I HGEm (P=0.001; P=0.01). The median disease-free survival for patients with heterologous CS was 15 months and had not been reached for women with homologous CS (P=0.001). The 3-year OS rates were 45% versus 93% in women with heterologous compared with homologous stage I CS (P90%. Homologous stage I CSs have survival outcomes that are similar to HGEm. This further supports the concept that homologous stage I CSs are carcinomas with sarcomatoid features, not sarcomas. More importantly, the presence of heterologous sarcomatous elements is a powerful negative prognostic factor in surgical stage I uterine CS.

  11. Efficacy and safety of Cimicifuga foetida extract on menopausal syndrome in Chinese women

    Institute of Scientific and Technical Information of China (English)

    ZHENG Ting-ping; SUN Ai-jun; XUE Wei; WANG Ya-ping; JIANG Ying; ZHANG Ying; LANG Jing-he

    2013-01-01

    Background It is now recognized that Cimicifuga foetida extract is effective in alleviating menopausal symptoms.But the durations reported were usually short.This paper compares the clinical effects of different regimens of three-month course on climacteric symptoms in Chinese women,so as to evaluate the efficacy and safety of Cimicifuga foetida extract.Methods This was a prospective,randomized trial.Ninety-six early menopausal women were recruited and randomly assigned into 3 groups to take different kinds of medicine for 3 months; participants were given Cimicifuga foetida extract daily in group A (n=32),given estradiol valerate and progesterone capsule cycle sequentially in group B (n=32),and given estradiol valerate and medroxyprogesterone acetate cycle sequentially in group C (n=32).The questionnaires of Kupperman menopause index,Menopause-Specific Quality of Life,and Hospital Anxiety and Depression Scale were finished before and after the treatment.The status of vaginal bleeding and breast tenderness was recorded every day.Results Eighty-nine participants (89/96,92.7%) completed the treatment.Kupperman menopause index decreased after taking the medicine for 3 months in each group (with all P<0.001),but the score after the treatment was higher in group A than in the other 2 groups.Except for the score of sexual domain in group A (P=0.103),the scores of all domains of the Menopause-Specific Quality of Life decreased significantly after the treatment in all groups (with all P≤-0.01).Score of anxity decreased significantly in group A (P=0.015) and B (P=0.003).Incidence of breast tenderness was 12.9% (4/31) in group A,36.7% (11/30) in group B,and 14.3% (4/28) in group C.Incidence of vaginal bleeding was 6.5% (2/31) in group A,26.7% (8/30) in group B,and 82.1% (23/28) in group C.Conclusions Cimicifuga foetida extract is effective and safe in the treatment of menopausal syndrome.It is worth extending its use in the treatment of climacteric

  12. Smokefree Women

    Science.gov (United States)

    ... infographic that presents all the benefits to quitting smoking during pregnancy to help you have a happy, healthy birth ... of smoke… Read full story: 3 Very Real Dangers of Secondhand Smoke » share 4 Benefits of Quitting Smoking Many women are surprised by how well… Read ...

  13. Rebellious Women

    DEFF Research Database (Denmark)

    Madsen, Peter

    2010-01-01

    At the background of a short presentation of concepts of discourse (in particular in Jürgen Habermas and Michel Foucault) and of the concept of shari'a a Spanish court case against an imam in reference to his publication on Women in Islam, where sura 4 verse 34 of the Quran is a central reference...

  14. Women's worth.

    Science.gov (United States)

    Bloch, N

    1992-01-01

    Jill Conway is a feminist historian, writer, teacher, and now-emerita 1st woman president of Smith College. She claims that women today still suffer from a great deal of oppression. Women around the world are currently in a disadvantage position. In 7 countries women do not have the right to vote. In the US less that .5% of top executives are women. The wage gap in the US between 1939 and 1989 has only shrunk $.10, from $.58-$.68. Conway points out that we are all constrained by our social mores, generational attitudes, political events, and economic circumstances. Few people are able to overcome these things in the way that they live their lives. Conway questions the validity of history written from a male dominated point of view. Around the world the value of women's work is almost always lower than that of men. India is just 1 example, there 75% of women are illiterate and 1/2 the population lives in poverty based on a caste system. Female literacy tripled in the 1st 30 years of independence and by 1981 it had reached 25%. The literacy gap is actually growing in India Today with 44% of girls aged 6 to 11, who are eligible to attend school, not doing so. Rural poverty keeps them at home because their domestic work is more valuable than their education. Other cultural tradition compound the problem: arranged marriages often result in motherhood for 14 year old girls. This is done for many reasons, 1 of which is crop failure insurance. When 2 families are combined through marriage, their total land share grows and they are thus more likely to have enough to eat. Education is just 1 necessary step. Developed nations must realize the realities that exist in the countries they provide aid for. In Africa for example, 70% of continent's food is produced by women. Yet the aid programs of the past have only been designed to offer assistant to men and create jobs for men.

  15. Representaciones socio-culturales sobre la menopausia: Vivencias del proceso en mujeres residentes en Albacete (España Socio-cultural representations about menopause: Experiences of the process in resident women in Albacete, Spain

    Directory of Open Access Journals (Sweden)

    Angélica Gómez Martínez

    2008-09-01

    Full Text Available Objetivo: Acercamiento a las representaciones sociales constitutivas de un fenómeno biológico-biográfico denominado climaterio, mediante los significados atribuidos por medio de los saberes, actitudes y comportamientos socioculturales de las mujeres en este periodo de su vida. Metodología: Estudio cualitativo mediante siete grupos focales (37 mujeres. Población de estudio: mujeres entre 45-55 años, residentes en la ciudad de Albacete. Resultados: proceso identificado con la edad biológica de las mujeres, con atributos negativos por su relación con el envejecimiento. Se relaciona también con la imagen social de la mujer y los roles socioculturales asignados clásicamente a este colectivo. Esta combinación de factores las conduce hacia un periodo de su vida tildado como "edad crítica", construcción en la que priman elementos biográficos sobre biológicos. Conclusión: Reconocer la "Variabilidad" de la vivencia del proceso. Esto entraría en conflicto con la actual tendencia biomédica, de protocolizar ciertas etapas relacionadas con el ciclo vital de las personas, intentando generar adscripciones unitarias basadas en entidades médicas construidas con fines operativos e instrumentales. Reconocer la "Vulnerabilidad" que supone la confluencia de diversas circunstancias, que las conducen, no sólo a enfrentarse con cambios físicos, emocionales y socioculturales, propios de esta etapa, sino a la realización de una evaluación retrospectiva crítica y profunda de la experiencia de vida, de la autobiografía.Objective: Approach to the social representations constituent of a biological-biographical phenomenon denominated climacteric, by means of the meanings attributed through socio-cultural knowledge, attitudes and behaviours of the woman in this period of their life. Methodology: Qualitative study by means of seven focal groups (37 women. Population of study: women between 45-55 years, residents in the city of Albacete. Results: Process

  16. Cervical Cancer Stage IVB

    Science.gov (United States)

    ... of the body, such as the lymph nodes, lung, liver, intestine, or bone. Stage IVB cervical cancer. Topics/Categories: Anatomy -- Gynecologic Cancer Types -- Cervical Cancer Staging Type: Color, ...

  17. Stages of Adolescence

    Science.gov (United States)

    ... Español Text Size Email Print Share Stages of Adolescence Page Content Article Body Adolescence, these years from puberty to adulthood, may be roughly divided into three stages: early adolescence, generally ages eleven to fourteen; middle adolescence, ages ...

  18. Stages of Esophageal Cancer

    Science.gov (United States)

    ... stage 0 , abnormal cells are found in the mucosa or submucosa layer of the esophagus wall. These ... found. Stage IA : Cancer has formed in the mucosa or submucosa layer of the esophagus wall. The ...

  19. Dynamic Stage Design

    Institute of Scientific and Technical Information of China (English)

    Florian von Hofen[GER

    2013-01-01

    Concepts and methods for dynamic stage designs were introduced ranging from different ifelds of TV live shows, exhibitions and theatre performances, and a special emphasis was put on solution to the theatre stage design.

  20. Ages and Stages: Teen

    Science.gov (United States)

    ... Spread the Word Shop AAP Find a Pediatrician Ages & Stages Prenatal Baby Toddler Preschool Gradeschool Teen Dating & ... Safety School Substance Abuse Young Adult Healthy Children > Ages & Stages > Teen Teen Article Body Adolescence can be ...

  1. Breast cancer staging

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000911.htm Breast cancer staging To use the sharing features on this ... Once your health care team knows you have breast cancer , they will do more tests to stage it. ...

  2. 216例晚期妊娠孕妇骨盆带疼痛特点及对日常生活影响分析%Characteristics of Pregnancy-related Pelvic Girdle Pain in Women during Late Stage of Pregnancy and Its Influence on Daily Life

    Institute of Scientific and Technical Information of China (English)

    潘雅珍

    2012-01-01

    Objective To explore the characteristics of pregnancy-related pelvic girdle pain (PPGP) in women during the late stage of pregnancy and its influence on daily life. Methods A cross-sectional study was conducted among 216 women during the late stage of pregnancy. The characteristics of pain and its influence on daily life were measured by Brief Pain Inventory (BPI). Socio-demographic characteristics and basic clinical information were also recorded. Results 157 patients (72.7%) reported pregnancy-related pelvic girdle pain and 74.5% of PPGP patients reported posterior pain. The average scores for worst and average PPGP were (6.3±2.2) and (4.5±1.9) respectively. The average score of pain influence on daily life was (3.9±2.3). The participants reported that pain exerted the greatest impact on sleep with a score of (5.8±3.1). Conclusion It is confirmed that pregnancy-related pelvic girdle pain exists commonly among women during the late stage of pregnancy, which keeps in a moderate level and has influence on daily life, especially on sleep.%目的 探讨晚期妊娠孕妇妊娠相关骨盆带疼痛(pregnancy-related pelvic girdle pain,PPGP)的特点及对日常生活的影响.方法 以晚期妊娠的216例孕妇作为研究对象,利用简明疼痛量表(Brief Pain Inventory,BPI)衡量妊娠相关骨盆带疼痛的程度和对日常生活的影响,同时记录研究对象的社会人口学特点和基本临床资料.结果 216例研究对象中有157例(72.7%)患有妊娠相关骨盆带疼痛,74.5%的孕妇疼痛部位位于骨盆后方,最强疼痛和平均疼痛的评分分别为(6.3±2.2)分和(4.5±1.9)分;对日常生活影响为(3.9±2.3)分,其中受疼痛影响最大的是睡眠,为(5.8±3.1)分.结论 晚期妊娠患者具有较高的妊娠相关骨盆带疼痛患病率,疼痛强度通常是中等程度,妊娠相关骨盆带疼痛对日常生活造成明显不良影响,尤其是对睡眠影响较大.

  3. An international randomised controlled trial to compare TARGeted Intraoperative radioTherapy (TARGIT) with conventional postoperative radiotherapy after breast-conserving surgery for women with early-stage breast cancer (the TARGIT-A trial).

    Science.gov (United States)

    Vaidya, Jayant S; Wenz, Frederik; Bulsara, Max; Tobias, Jeffrey S; Joseph, David J; Saunders, Christobel; Brew-Graves, Chris; Potyka, Ingrid; Morris, Stephen; Vaidya, Hrisheekesh J; Williams, Norman R; Baum, Michael

    2016-01-01

    BACKGROUND Based on our laboratory work and clinical trials we hypothesised that radiotherapy after lumpectomy for breast cancer could be restricted to the tumour bed. In collaboration with the industry we developed a new radiotherapy device and a new surgical operation for delivering single-dose radiation to the tumour bed - the tissues at highest risk of local recurrence. We named it TARGeted Intraoperative radioTherapy (TARGIT). From 1998 we confirmed its feasibility and safety in pilot studies. OBJECTIVE To compare TARGIT within a risk-adapted approach with whole-breast external beam radiotherapy (EBRT) over several weeks. DESIGN The TARGeted Intraoperative radioTherapy Alone (TARGIT-A) trial was a pragmatic, prospective, international, multicentre, non-inferiority, non-blinded, randomised (1 : 1 ratio) clinical trial. Originally, randomisation occurred before initial lumpectomy (prepathology) and, if allocated TARGIT, the patient received it during the lumpectomy. Subsequently, the postpathology stratum was added in which randomisation occurred after initial lumpectomy, allowing potentially easier logistics and a more stringent case selection, but which needed a reoperation to reopen the wound to give TARGIT as a delayed procedure. The risk-adapted approach meant that, in the experimental arm, if pre-specified unsuspected adverse factors were found postoperatively after receiving TARGIT, EBRT was recommended. Pragmatically, this reflected how TARGIT would be practised in the real world. SETTING Thirty-three centres in 11 countries. PARTICIPANTS Women who were aged ≥ 45 years with unifocal invasive ductal carcinoma preferably ≤ 3.5 cm in size. INTERVENTIONS TARGIT within a risk-adapted approach and whole-breast EBRT. MAIN OUTCOME MEASURES The primary outcome measure was absolute difference in local recurrence, with a non-inferiority margin of 2.5%. Secondary outcome measures included toxicity and breast cancer-specific and non

  4. Beyond Erikson's Eight Stages.

    Science.gov (United States)

    Whitney, Ruth

    1979-01-01

    Erik Erikson has described eight stages of the healthy personality. This essay offers a revised version of the eight stages. Although most individuals develop through the eight stages, each is personally unique because patterns of fluctuation between safety and growth differ from one individual to another. (Author)

  5. Ovarian Cancer Stage II

    Science.gov (United States)

    ... hyphen, e.g. -historical Searches are case-insensitive Ovarian Cancer Stage II Add to My Pictures View /Download : ... 1650x675 View Download Large: 3300x1350 View Download Title: Ovarian Cancer Stage II Description: Three-panel drawing of stage ...

  6. Ovarian Cancer Stage IIIC

    Science.gov (United States)

    ... hyphen, e.g. -historical Searches are case-insensitive Ovarian Cancer Stage IIIC Add to My Pictures View /Download : ... 1530x1350 View Download Large: 3060x2700 View Download Title: Ovarian Cancer Stage IIIC Description: Drawing of stage IIIC shows ...

  7. Ovarian Cancer Stage I

    Science.gov (United States)

    ... hyphen, e.g. -historical Searches are case-insensitive Ovarian Cancer Stage I Add to My Pictures View /Download : ... 1650x675 View Download Large: 3300x1350 View Download Title: Ovarian Cancer Stage I Description: Three-panel drawing of stage ...

  8. Women's Club

    CERN Multimedia

    CERN Women's Club

    2012-01-01

     Coffee Morning Tuesday 7th February 2012, 9:00 – 11:00 Bldg 504 (Restaurant n°2 – DSR) 1st Floor, Club Room 3 Presentation of cheque to Terre des Hommes Those interested in helping should come along. New arrivals and all members are cordially invited.You can enrol for membership, renew membership, find out about and sign up for our activities. Visit our website: http://club-womensclub.web.cern.ch/Club-WomensClub/

  9. Women's club

    CERN Multimedia

    Club des cernoises

    2012-01-01

    Coffee MorningTuesday 9th October 2012, 9:00 – 11:00 Bldg 504 (Restaurant No 2 – DSR) 1st Floor, Club Room 3 Presentation of the charity to benefit from the Christmas Sale “Nous aussi”. Those interested in helping should come along. New arrivals and all members are cordially invited. You can enrol for membership, renew membership, find out about and sign up for our activities. Visit our website: http://cern.ch/Club-WomensClub/

  10. Women's Club

    CERN Multimedia

    Women's Club

    2014-01-01

        CERN WOMEN’S CLUB Coffee Morning Tuesday 8th Avril 2014, 9:30 – 14:00 Bldg 504 (Restaurant No 2 – DSR) Ground Floor Spring Jumble Sale   Those interested in helping should come along. New arrivals and all members are cordially invited. You can enrol for membership, renew membership, find out about and sign up for our activities. Visit our website: http://cern.ch/Club-WomensClub/

  11. Women's Club

    CERN Multimedia

    Club des Cernoises

    2012-01-01

    Coffee Morning   Tuesday 24th  April 2012, 9:00 – 14:00 Bldg 504, Ground Floor Spring Jumble Sale   Those interested in helping should come along. New arrivals and all members are cordially invited. You can enrol for membership, renew membership, find out about and sign up for our activities. Visit our website: http://club-womensclub.web.cern.ch/Club-WomensClub/

  12. Women's Club

    CERN Multimedia

    Club des Cernoises

    2012-01-01

    Coffee Morning Tuesday 13th  March 2012, 9:00 – 11:00 - Bldg 504 (Restaurant No 2 – DSR) - 1st Floor, Club Room 3. German Theme Those interested in helping should come along. New arrivals and all members are cordially invited. You can enrol for membership, renew membership, find out about and sign up for our activities. Visit our website: http://club-womensclub.web.cern.ch/Club-WomensClub/     CWC – Chinese Women's Community at CERN With an increasing number of Chinese people working at CERN, there are also surely an increasing number of Chinese women in the area, who are not always familiar with the environment, languages, or the people. In the context of the CERN Women’s Club, let's meet together and chat about integrating into the local community, available activities, commerce’s, restaurants, etc. It is also obviously a good opportunity to meet new friends. Everyone is welcome to join us to meet fo...

  13. Women's club

    CERN Multimedia

    Club des Cernoises

    2012-01-01

        CWC – Chinese Women's Community at CERN With an increasing number of Chinese people working at CERN, there are also surely an increasing number of Chinese women in the area, who are not always familiar with the environment, languages, or the people. In the context of the CERN Women’s Club, let's meet together and chat about integrating into the local community, available activities, commerce’s, restaurants, etc. It is also obviously a good opportunity to meet new friends. Everyone is welcome to join us to meet for tea, coffee, and a chat. We will meet every 3rd Tuesday of the month, starting on 20th March 2012, in building 504 (Restaurant 2) in room E-005. 20th March at 9-11am 17th April at 9-11am 22nd May at 9-11am 19th June at 9-11am For more details contact Mme Jean RODERICK, +41 (0) 76 426 61 08, jean.chow.roderick@gmail.com http://club-womensclub.web.cern.ch/Club-WomensClub/     CWC-華人茶敍 越來�...

  14. Prolactin and cortisol levels in women with endometriosis

    Directory of Open Access Journals (Sweden)

    A.P. Lima

    2006-08-01

    Full Text Available Endometriosis is a progressive estrogen-dependent disease affecting women during their reproductive years. The objective of the present study was to investigate whether endometriosis is associated with stress parameters. We determined cortisol and prolactin levels in serum, peritoneal and follicular fluid from infertile women with endometriosis and fertile women without the disease. The extent of the disease was staged according to the revised American Fertility Society classification (1997. Serum and peritoneal fluid were collected from 49 women aged 19 to 39 years undergoing laparoscopy. Eighteen women had stage I-II endometriosis and 10 had stage III-IV. Controls were 21 women undergoing laparoscopy for tubal sterilization. Follicular fluid was obtained from 39 women aged 25-39 years undergoing in vitro fertilization (21 infertile women with endometriosis and 18 infertile women without endometriosis. Serum prolactin levels were significantly higher in infertile women with stage III-IV endometriosis (28.9 ± 2.1 ng/mL than in healthy controls (13.2 ± 2.1 ng/mL. Serum cortisol levels were significantly higher in infertile women with stage III-IV endometriosis (20.1 ± 1.3 ng/mL than in controls (10.5 ± 1.4 ng/mL. Cortisol and prolactin levels in follicular fluid and peritoneal fluid did not differ significantly between groups. The high levels of cortisol and prolactin in the serum from women with endometriosis might contribute to the subfertility frequently associated with the disease. Moreover, since higher levels of cortisol and prolactin are often associated with stress, it is probable that stress might contribute to the development of endometriosis and its progression to advanced stages of the disease.

  15. Prolactin and cortisol levels in women with endometriosis.

    Science.gov (United States)

    Lima, A P; Moura, M D; Rosa e Silva, A A M

    2006-08-01

    Endometriosis is a progressive estrogen-dependent disease affecting women during their reproductive years. The objective of the present study was to investigate whether endometriosis is associated with stress parameters. We determined cortisol and prolactin levels in serum, peritoneal and follicular fluid from infertile women with endometriosis and fertile women without the disease. The extent of the disease was staged according to the revised American Fertility Society classification (1997). Serum and peritoneal fluid were collected from 49 women aged 19 to 39 years undergoing laparoscopy. Eighteen women had stage I-II endometriosis and 10 had stage III-IV. Controls were 21 women undergoing laparoscopy for tubal sterilization. Follicular fluid was obtained from 39 women aged 25-39 years undergoing in vitro fertilization (21 infertile women with endometriosis and 18 infertile women without endometriosis). Serum prolactin levels were significantly higher in infertile women with stage III-IV endometriosis (28.9 +/- 2.1 ng/mL) than in healthy controls (13.2 +/- 2.1 ng/mL). Serum cortisol levels were significantly higher in infertile women with stage III-IV endometriosis (20.1 +/- 1.3 ng/mL) than in controls (10.5 +/- 1.4 ng/mL). Cortisol and prolactin levels in follicular fluid and peritoneal fluid did not differ significantly between groups. The high levels of cortisol and prolactin in the serum from women with endometriosis might contribute to the subfertility frequently associated with the disease. Moreover, since higher levels of cortisol and prolactin are often associated with stress, it is probable that stress might contribute to the development of endometriosis and its progression to advanced stages of the disease.

  16. Women's health and feminist politics.

    Science.gov (United States)

    Faure, D

    1994-06-01

    The Sempreviva Organizacao Feminista (SOF) has aimed since 1963 to improve women's health in low-income communities in southeastern Brazil. There is concern for the whole person in all stages of a woman's life, not just the reproductive one commonly addressed in population control programs. SOF has linked gender, health, and poverty and contributed to social movements to improve conditions. SOF's constituency is about 90% women aged 20-40 years, with 2-5 children, and a lack of education. About 70% remain in the home caring for their families, and 25% are employed formally or informally. The women's fertility rates are high and they desire to limit childbearing. Most women are unaware of their own reproductive physiology and had not discussed sex with their parents before marriage. Active membership by 1971 was 7600 members. SOF's present aims are to strengthen the women's movement, to develop feminist approaches to health issues, to implement a women's health program, and to incorporate gender issued into other social movements. The present goals evolved out of the initial program of offering health services and family planning in a suburb of Sao Paulo. After break with their funding agency in 1967, over the refusal to promote female sterilization, they found funding by the World Council of Churches and others, which opened the doors to improvement in the quality of care. Meetings held every 2 years provide a forum for involvement of grassroots groups. The National Feminist Network for Health and Reproductive Rights provides the integrating mechanism for feminist nongovernmental groups and pressures the national government for reforms that will benefit women. SOF is just one of the grassroots organizations that offers collective and innovative experiences and empowerment. Social movements in the south and west of Sao Paulo have become more organized and demanded better public health policy or improvements in sanitation and waste disposal. SOF is currently

  17. Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer

    Science.gov (United States)

    2014-12-29

    Cervical Adenocarcinoma; Cervical Adenosquamous Carcinoma; Cervical Small Cell Carcinoma; Cervical Squamous Cell Carcinoma; Stage IB Cervical Cancer; Stage IIA Cervical Cancer; Stage IIB Cervical Cancer; Stage III Cervical Cancer; Stage IVA Cervical Cancer

  18. Experimental Study on Influence Xuzao Gengping Prescription in Sex Hormones of Female Rats Climacteric Hypertension%虚燥更平方对雌性大鼠高血压病(更年期)性激素影响的实验研究

    Institute of Scientific and Technical Information of China (English)

    周丽萍; 林雪

    2011-01-01

    Obctiveje: To study the clinical efficacy of Xuzao Gengping Prescription on the female climacteric hypertension rats and analyzes theirs sex hormones index before and after the treatment, observe the changes of index.To explore on influence Xuzao Gengping prescription in sex hormones.Methods:the female climacteric hypertension rat model, Randomly divided into blank group, Chinese traditional medicine group, the model group, observe three group, estrogen ( E2 ), follicle-stimulating hormone ( FSH ),T ( testosterone ), corpus luteum ( LH ), progesterone ( PRO ), prolactin ( PRL )level, and statistical analysis is made.Results: Xuzao Gengping Prescription can make the female rat climacteric hypertension of Chinese traditional medicine group after the treatment, E2 raiseded levels, T, FSH reduced levels, a statistically significant ( P<0.05 ), PRO, PRL, LH was not statistically significant ( P>0.05 ).Conclusions:( 1 )Xuzao Gengping Prescription has certainly regulate function to improve the levels of sex hormones of female climacteric hypertension.( 2 ) Through the Chinese traditional medicine group and the model group related indexes and levels of sex hormones, female climacteric hypertension rats with the occurrence and development of hypertension relation, disorder sex hormone index may participate the patho-physiological course of menopausal hypertension in female.%目的:运用虚燥更平方作用于治疗雌性大鼠高血压病(更年期),观察大鼠性激素指标治疗前后的变化,探讨虚燥更平方对性激素的影响.方法:将雌性大鼠高血压病(更年期)模型,随机分成空白组、模型组、中药组,观察3组雌激素(E2)、促卵泡刺激素(FSH)、睾酮(T)、促黄体生成素(LH)、孕酮(PRO)、催乳素(PRL)水平,并做统计分析比较.结果:虚燥更平方可使雌性大鼠高血压病(更年期)中药组治疗后血清E2水平升高,T、FSH水平降低,三者有统计学意义(P0.05).结论:(1)虚燥更平方对改善

  19. Traditional Chinese Medicine Treats Menopause

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    THE climacteric in women, often referred to as menopause, generally occurs between the ages of 45 and 55. The ailment people most commonly or frequently encountered during this period is women’s climacteric syndrome with senile osteoporosis and senile depression next. The illness rate of the women’s climacteric syndrome is about 87.5 percent in China.

  20. Influência dos sintomas climatéricos sobre a função sexual de mulheres de meia-idade Influence of menopausal symptoms on sexual function in middle-aged women

    Directory of Open Access Journals (Sweden)

    Patrícia Uchôa Leitão Cabral

    2012-07-01

    Full Text Available OBJETIVO: Avaliar a influência dos sintomas climatéricos na função sexual de mulheres de meia-idade. MÉTODOS: Estudo populacional de corte transversal, com amostra de 370 mulheres entre 40 e 65 anos, atendidas nas Unidades Básicas de Saúde da cidade de Natal, no estado do Rio Grande do Norte, Brasil. Aplicou-se um questionário referente s características sociodemográficas, clínicas e comportamentais das mulheres. A função sexual foi avaliada pelo Female Sexual Function Index (FSFI, enquanto os sintomas do climatério pelo Menopause Rating Scale (MRS. RESULTADOS: No grupo estudado, 67% das mulheres apresentaram risco de disfunção sexual (FSFI≤26,5. Todos os domínios do FSFI (desejo, excitação, lubrificação, orgasmo, satisfação e dor apresentaram escores mais baixos nas mulheres com risco de disfunção sexual (pPURPOSE: To evaluate the influence of climacteric symptoms on the sexual function in middle-aged women. METHODS: A cross-sectional population study was conducted on a sample of 370 middle-aged women, aged 40 to 65 years-old, cared for at the Basic Health Units in Natal, in the state of Rio Grande do Norte, Brazil. We used a questionnaire containing questions on sociodemographic, clinical, and behavioral characteristics. Sexual function was evaluated by the Female Sexual Function Index (FSFI, while the menopause symptoms by the Menopause Rating Scale (MRS. RESULTS: In the studied group, 67% of the women reported risk for sexual dysfunction (FSFI≤26.5. All FSFI domains (desire, arousal, lubrication, orgasm, satisfaction, and pain were lower in women with risk for sexual dysfunction (p<0.001. The arousal, orgasm, and pain domains were most likely to contribute to lower FSFI scores. All somatovegetative, urogenital, and psychological MRS symptoms were more elevated in women with risk for sexual dysfunction, being significant for all comparisons (p<0.001. Logistic regression analysis revealed that the likelihood of

  1. Staged electrostatic precipitator

    Science.gov (United States)

    Miller, Stanley J.; Almlie, Jay C.; Zhuang, Ye

    2016-03-01

    A device includes a chamber having an air inlet and an air outlet. The device includes a plurality of stages including at least a first stage adjacent a second stage. The plurality of stages are disposed in the chamber and each stage has a plurality of discharge electrodes disposed in an interior region and is bounded by an upstream baffle on an end proximate the air inlet and bounded by a downstream baffle on an end proximate the air outlet. Each stage has at least one sidewall between the upstream baffle and the downstream baffle. The sidewall is configured as a collection electrode and has a plurality of apertures disposed along a length between the upstream baffle and the downstream baffle. The upstream baffle of the first stage is positioned in staggered alignment relative to the upstream baffle of the second stage and the downstream baffle of the first stage are positioned in staggered alignment relative to the downstream baffle of the second stage.

  2. Breast cancer in young women: poor survival despite intensive treatment.

    Directory of Open Access Journals (Sweden)

    Hanna Fredholm

    Full Text Available BACKGROUND: Breast cancer is uncommon in young women and correlates with a less favourable prognosis; still it is the most frequent cancer in women under 40, accounting for 30-40% of all incident female cancer. The aim of this study was to study prognosis in young women, quantifying how much stage at diagnosis and management on the one hand, and tumour biology on the other; each contribute to the worse prognosis seen in this age group. METHODOLOGY/PRINCIPAL FINDINGS: In a registry based cohort of women aged 20-69 (n = 22 017 with a primary diagnosis of invasive breast cancer (1992-2005, women aged 20-34 (n = 471, 35-39 (n = 858 and 40-49 (n = 4789 were compared with women aged 50-69 years (n = 15 899. The cumulative 5-year relative survival ratio and the relative excess mortality (RER were calculated. The cumulative 5-year relative survival ratio was lowest in women aged 20-34. The RER was 2.84 for women aged 20-34 and decreased with increasing age (RER 1.76 and 1.17 for women aged 35-39 and 40-49, respectively. The excess risk was, however, present only in disease stages I and II. For women aged 20-34 with stage I disease RER was 4.63, and 6.70 in the subgroup with tumour size 1-10 mm. The absolute difference in stage I between the youngest and the reference groups amounted to nearly 8%, with a 90% 5-year survival in women aged 20-34. In stages IIa and IIb, the relative excess risk was not as dramatic, but the absolute differences approached 15%. The youngest women with small tumours generally received more aggressive treatment than women in older age groups. CONCLUSIONS: After correction for stage, tumour characteristics and treatment, age remained an independent risk factor for breast cancer death in women <35 years of age. The excess risk for young women was only seen in early stages of disease and was most pronounced in women with small tumours. Young women affected by breast cancer have a high risk of dying compared to their middle

  3. Staging Mobilities / Designing Mobilities

    DEFF Research Database (Denmark)

    Jensen, Ole B.

    2015-01-01

    In recent years, urban research has taken a ‘mobilities turn’. There has been a developing realisation that mobilities do not ‘just happen.’ Mobilities are carefully and meticulously designed, planned and staged (from above). However, they are equally importantly acted out, performed and lived...... as people are ‘staging themselves’ (from below). Staging mobilities is a dynamic process between ‘being staged’ (for example, being stopped at traffic lights) and the ‘mobile staging’ of interacting individuals (negotiating a passage on the pavement). Staging mobilities is about the fact that mobility...... asks: what are the physical, social, technical, and cultural conditions to the staging of contemporary urban mobilities? The theoretical framing in the Staging mobilities book is applied to four in-depth cases in the accompanying volume Designing mobilities.This book explore how places, sites...

  4. Changing roles of women: reproduction to production.

    Science.gov (United States)

    Rachapaetayakom, J

    1988-12-01

    The status of women in the countries included in the Economic and Social Commission for Asia and the Pacific (ESCAP) varies widely from home labor and childbearing to social and political participation. In countries where the total fertility rate is high (over 6), such as Bangladesh, Pakistan, and Nepal, the status of women is low. Bangladesh, Pakistan, and Nepal, along with India, Sri Lanka, and China, also have the lowest levels of per capita income. The education of women is one of the earmarks of social development. Education enables women to delay marriage, reduce fertility, and participate in the economy. Between 1970 and 1980, the female literacy rate increased 10% in Thailand, Singapore, Malaysia, Sri Lanka, and the Philippines; and 5% in Bangladesh, Pakistan, and Nepal. Women's participation in the labor force is determined both by the stage of development of the country and by cultural factors. In Muslim countries the level of women's participation in the labor force is low. In Thailand and China it is very high. Women with the most education are likeliest to work in professional and administrative jobs. Self-employed women tend to have as little status and as many children as unpaid family workers, and women working in agriculture are almost as badly off. In Asia and the Pacific, except for Muslim countries, women have participated actively in family planning programs. In several countries in the region, women have been active in politics, but mostly at the local level. If women are to be integrated into the development process in the countries of Asia and the Pacific, attention must be given to their education and employment, to increasing the role of men in household and child rearing duties, and to research in the interrelations of population processes, women's status, and socioeconomic development.

  5. Access to women's health care: a qualitative study of barriers perceived by homeless women.

    Science.gov (United States)

    Gelberg, Lillian; Browner, C H; Lejano, Elena; Arangua, Lisa

    2004-01-01

    Homelessness is an escalating national problem and women are disproportionately affected. Nevertheless, few studies have focused on the special circumstances associated with being a homeless woman. For instance, while both genders experience serious barriers to obtaining health care, homeless women face an additional burden by virtue of their sexual and reproductive health needs. The current study was conducted as the first stage of a qualitative/quantitative investigation of homeless women's access and barriers to family planning and women's health care. We interviewed 47 homeless women of diverse ages and ethnic backgrounds. A qualitative approach was initially taken to explore the factors homeless women themselves perceive as barriers to their use of birth control and women's health services, and factors they believe would facilitate their use. Key findings are that health is not a priority for homeless women, that transportation and scheduling can be particularly burdensome for homeless women, and that being homeless leads some to feel stigmatized by health care providers. Despite being homeless, having children was extremely important to the women in our study. At the same time, those interested in contraception confronted significant barriers in their efforts to prevent pregnancies. We conclude with suggested interventions that would make general, gynecological, and reproductive health care more accessible to homeless women.

  6. Lymphadenectomy in surgical stage I epithelial ovarian cancer

    DEFF Research Database (Denmark)

    Svolgaard, Olivia; Lidegaard, Ojvind; Nielsen, Marie Louise S;

    2014-01-01

    OBJECTIVE: To identify the extent of lymphadenectomy performed in women presenting with epithelial ovarian cancer macroscopically confined to the ovary. Furthermore, the effect of lymphadenectomy on overall survival is evaluated. DESIGN: A prospective nationwide case-only study. SETTING: Denmark......: Descriptive and survival analyses of data from Danish Gynecologic Cancer Database. MAIN OUTCOME MEASURES: The annual proportion of women with surgical stage I disease who received lymphadenectomy and the survival in the two groups. RESULTS: Of 2361 women with epithelial ovarian cancer, 627 were identified...... 2005-2011. SAMPLE: All women registered in the nationwide Danish Gynecologic Cancer Database from 1 January 2005 to 1 May 2011, presenting with a tumor macroscopically confined to the ovary without visible evidence of abdominal spread at the time of the initial exploration (surgical stage I). METHOD...

  7. Effects of Socio-Demographic, Personality and Medical Factors on Quality of Life of Postmenopausal Women

    Science.gov (United States)

    Wieder-Huszla, Sylwia; Szkup, Małgorzata; Jurczak, Anna; Samochowiec, Agnieszka; Samochowiec, Jerzy; Stanisławska, Marzanna; Rotter, Iwona; Karakiewicz, Beata; Grochans, Elżbieta

    2014-01-01

    Numerous studies show that changes occurring in a woman’s organism during menopause may lower her quality of life. This study involved 630 healthy postmenopausal women from Poland. Its purpose was to assess their quality of life in relation to socio-demographic variables, medical data and personality profiles. The authors used the Short Form Health Survey (SF-36) to assess quality of life, the NEO-Five Factor Inventory to measure personality traits, and the Blatt-Kupperman Menopausal Index to estimate severity of climacteric symptoms. The study demonstrated significant relationships between quality of life and variables such as: age, education, employment status, and the use of menopausal hormone therapy. An analysis of personality traits revealed correlations between the openness to experience scores and the quality of life within physical functioning, vitality, and mental health. Neuroticism, agreeableness and extroversion significantly correlated with all quality of life domains. Conclusions: (1) Age, education and employment status have significant effects on the selected quality of life domains after menopause. (2) Quality of life within the general health domain was assessed lower by MHT-users (Menopausal hormone theraphy (MHT)). (3) Health-related quality of life is also influenced by personality traits, which are relatively stable throughout life. PMID:24972032

  8. Effects of Socio-Demographic, Personality and Medical Factors on Quality of Life of Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Sylwia Wieder-Huszla

    2014-06-01

    Full Text Available Numerous studies show that changes occurring in a woman’s organism during menopause may lower her quality of life. This study involved 630 healthy postmenopausal women from Poland. Its purpose was to assess their quality of life in relation to socio-demographic variables, medical data and personality profiles. The authors used the Short Form Health Survey (SF-36 to assess quality of life, the NEO-Five Factor Inventory to measure personality traits, and the Blatt-Kupperman Menopausal Index to estimate severity of climacteric symptoms. The study demonstrated significant relationships between quality of life and variables such as: age, education, employment status, and the use of menopausal hormone therapy. An analysis of personality traits revealed correlations between the openness to experience scores and the quality of life within physical functioning, vitality, and mental health. Neuroticism, agreeableness and extroversion significantly correlated with all quality of life domains. Conclusions: (1 Age, education and employment status have significant effects on the selected quality of life domains after menopause. (2 Quality of life within the general health domain was assessed lower by MHT-users (Menopausal hormone theraphy (MHT. (3 Health-related quality of life is also influenced by personality traits, which are relatively stable throughout life.

  9. Effect of Bushen Zhuanggu Granules upon Gonadal Hormone and Blood Fat in Climacteric Females%补肾壮骨冲剂对更年期综合征患者性激素及血脂的影响

    Institute of Scientific and Technical Information of China (English)

    邓伟民; 黄海; 曾东; 李晓昊; 张金玉; 邵玉; 周丽; 黄伟毅; 韩丽萍

    2011-01-01

    Objective To observe the effect of Bushen Zhuanggu Granules (Herbal granules for reinforcing kidney to strengthen bones) upon gonadal hormone and vasomotor symptoms of climacteric females. Methods Totally 582 postmenopausal outpatients were randomized into Chinese medicine group of 285 cases and western drug group of 297 cases. The Chinese medicine group was treated with Bushen Zhuanggu Granules and the western drug group was with premarin and provera.The main observed indices were blood fat including total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C), gonadal hormones including estradiol (E2), follicle stimulating hormone (FSH), and luteinizing hormone (LH), and the changes in scores of symptoms and signs before and after treatment. Results There were 63 dropouts in the Chinese medicine group after a half-year's treatment, and 94 dropouts in the western drug group, the difference between the two groups was significant (P<0.01). The total effective rate of the Chinese medicine group was 82.87%, while that of the western drug group was 73.12%, there was significant difference between the two groups after treatment (P<0.05). The total symptom score of both groups was significantly decreased after treatment (P<0.05 or P<0.01 ), but the Chinese medicine group was superior to the western drug group (P<0.01). Changes of gonadal hormone and blood fat of both groups after treatment was significant, showing a statistical difference (P<0.05). Conclusion Bushen Zhuanggu Granules can effectively regulate gonadal hormone and blood fat in climacteric females, with a similar function of western estrogen replacement therapy, but without untoward effect.%目的 观察补肾壮骨冲剂对更年期综合征患者性激素及血脂的影响. 方法 将582例患者随机分为中药组285例和西药组297例.中药组口服补肾壮骨冲剂治疗,西药组应用倍美力加安宫

  10. Prevalence of hypertension among reproductive age group tribal women in Visakhapatnam district, Andhra Pradesh, India

    Directory of Open Access Journals (Sweden)

    S. Appala Naidu

    2016-04-01

    Results: Among the study women, 40.6% belonged to prime tribe groups (PTG and 36% of women had debts. Two fifths (40.7% of tribal women were normotensive and another two fifths (42.1% were in pre-hypertensive stage. Stage-1 hypertension was observed in 16.3% of study women. Non- PTGs and women with debts had significantly high prevalence of hypertension when compared to other groups. Conclusions: Prevalence of HTN was more in tribal women when compared to national prevalence indicating the need of screening of blood pressures in tribal communities. [Int J Res Med Sci 2016; 4(4.000: 1224-1228

  11. Ganglion sentinelle et sentibras: pour un "staging" axillaire sur mesure

    OpenAIRE

    2011-01-01

    The status of the axillary lymph nodes is one of the most important prognostic factors in women with early stage breast cancer. Histologic examination of removed lymph nodes is the most accurate method for assessing spread of disease to these nodes. Axillary lymph node dissection (ALND) remains the standard approach for women who have clinically palpable axillary nodes. The benefits of ALND include its impact on disease control (axillary recurrence and survival), its prognostic value, and its...

  12. Why the Scientific Pipeline Is Still Leaking? Women Scientists and Their Work-Life Balance in Poland

    Science.gov (United States)

    Polkowska, Dominika

    2014-01-01

    In the contemporary scholarly discourse, the under-representation of women in science is often explained by the phenomenon of women "in the pipeline". The pipeline carries a flow from one stage to another, and the flow of women diminishes between the stages. Based on the literature and qualitative studies, it can be inferred that one of…

  13. Rural Women Get Help from Women Students

    Institute of Scientific and Technical Information of China (English)

    JANE SHAW

    1994-01-01

    SINCE more and more rural women have become involved in commercial production, they have become more and more eager to learn about scientific technology. The Women’s Federation of Beijing had long been looking for a direct and effective way to help them. Luo Xiaolu, vicedirector of the Federation, found in her investigation of the present conditions of intellectual women in Beijing that women students were also eager to get in touch with society. Then she had an idea that women students in universities and colleges should go to the countryside. Thus, an activity developed called "women college students and rural women, hand in hand."

  14. Multiple Stages 2

    DEFF Research Database (Denmark)

    Andreasen, John

    Multiple stages 2: theatrical futures, set design, community plays, cultural capitals, democracy & drama, WWII dramas, performance on adoption, promenade about emigration, qualities in political theatre, performance analysis, dramaturgical education, Toulmin Variations......Multiple stages 2: theatrical futures, set design, community plays, cultural capitals, democracy & drama, WWII dramas, performance on adoption, promenade about emigration, qualities in political theatre, performance analysis, dramaturgical education, Toulmin Variations...

  15. Unsettled women.

    Science.gov (United States)

    Coleman, J

    2001-01-01

    SUMMARY Amy Bock (alias Percy Redwood) created a media sensation when "The Case of the Woman Bridegroom" hit the newspapers throughout New Zealand in 1909. She was hailed as the "queerest and most interesting character that has ever been before the New Zealand public" and "pitiable in her freakish exploits." Debates ensued as to whether her crimes were evidence of a mania, a disease, or simply due to a flawed, criminal character. This article focuses on media portrayals of women who did not conform to normative constructions of acceptable womanhood within the latter decades of the nineteenth century and the early twentieth century in New Zealand, as a means of tracing the mutable boundaries of intelligible genders. Newspaper debates and emergent discourses around the medicalisation of social de-viancy are drawn upon to demonstrate how normative constructions of gender were premised upon a defining matrix of mad/bad/woman.

  16. Women and Diabetes

    Science.gov (United States)

    ... Audience For Women Women's Health Topics Women and Diabetes Share Tweet Linkedin Pin it More sharing options ... Diabetes How to Report Problems with Glucose Meters Diabetes Treatments Some people with diabetes need to take ...

  17. Women and Diabetes

    Medline Plus

    Full Text Available ... Audience For Women Women's Health Topics Women and Diabetes Share Tweet Linkedin Pin it More sharing options ... Diabetes How to Report Problems with Glucose Meters Diabetes Treatments Some people with diabetes need to take ...

  18. Women and HIV

    Science.gov (United States)

    ... Consumer Information by Audience For Women Women and HIV Share Tweet Linkedin Pin it More sharing options ... HIV? What should pregnant women know about HIV? HIV Quick Facts What is HIV? HIV is the ...

  19. Competition between Women.

    Science.gov (United States)

    Joseph, R.

    1985-01-01

    Examined competition and physical attractiveness among women. Results indicated that a large number of females are highly critical of other women, particularly attractive ones, and are highly concerned about their own appearance in relation to other women. (Author/BL)

  20. Women and Industrial Education

    Science.gov (United States)

    Bjorkquist, David C.

    1973-01-01

    Deals with these three questions: (1) What is the employment status of women, (2) What do advocates of the women's rights movement want, (3) How should industrial educators respond to the women's rights movement? (SB)

  1. Minority Women and Advocacy for Women's Health

    Science.gov (United States)

    Kumanyika, Shiriki K.; Morssink, Christiaan B.; Nestle, Marion

    2001-01-01

    US minority health issues involve racial/ethnic disparities that affect both women and men. However, women's health advocacy in the United States does not consistently address problems specific to minority women. The underlying evolution and political strength of the women's health and minority health movements differ profoundly. Women of color comprise only one quarter of women's health movement constituents and are, on average, socioeconomically disadvantaged. Potential alliances may be inhibited by vestiges of historical racial and social divisions that detract from feelings of commonality and mutual support. Nevertheless, insufficient attention to minority women's issues undermines the legitimacy of the women's health movement and may prevent important advances that can be achieved only when diversity is fully considered. PMID:11527764

  2. Women of ATLAS - International Women's Day 2016

    CERN Multimedia

    Biondi, Silvia

    2016-01-01

    Women play key roles in the ATLAS Experiment: from young physicists at the start of their careers to analysis group leaders and spokespersons of the collaboration. Celebrate International Women's Day by meeting a few of these inspiring ATLAS researchers.

  3. PECULIARITIES OF FORMATION OF WOMEN'S POLITICAL RIGHTS IN RUSSIA

    Directory of Open Access Journals (Sweden)

    Yarmonona E. N.

    2014-10-01

    Full Text Available The article reveals the story of the formation of the political rights of women in various stages of development of the Russian society. Author focuses the attention on the impact of the social status of women on its ability to participate in political life and foreign policy

  4. Stages of Gallbladder Cancer

    Science.gov (United States)

    ... cancer. Tests that examine the gallbladder and nearby organs are used to detect (find), diagnose, and stage ... cancer cells or to make cancer cells more sensitive to the effects of radiation therapy and certain ...

  5. Late-Stage Caregiving

    Science.gov (United States)

    ... resources, care and ways to engage in meaningful connections. During the late stages, your role as a ... drinks. This will help you track the person's natural routine, and then you can plan a schedule. ...

  6. Understanding cancer staging

    Science.gov (United States)

    ... Manual and Handbook . 2nd ed. New York, NY: Springer; 2012. National Cancer Institute. Staging. Updated March 9, ... medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- ...

  7. Staged bilateral carotid endarterectomy

    DEFF Research Database (Denmark)

    Schroeder, T; Sillesen, H; Engell, Hans Christian

    1986-01-01

    In a series of 56 staged bilateral carotid endarterectomies, new neurologic symptoms developed in 5% and 20% following the first and second procedure, respectively. All complications were transient or minor. The incidence of postendarterectomy hypertension was significantly higher following...

  8. Normalization: A Preprocessing Stage

    OpenAIRE

    Patro, S. Gopal Krishna; Sahu, Kishore Kumar

    2015-01-01

    As we know that the normalization is a pre-processing stage of any type problem statement. Especially normalization takes important role in the field of soft computing, cloud computing etc. for manipulation of data like scale down or scale up the range of data before it becomes used for further stage. There are so many normalization techniques are there namely Min-Max normalization, Z-score normalization and Decimal scaling normalization. So by referring these normalization techniques we are ...

  9. Respiratory Contribution of the Alternate Path during Various Stages of Ripening in Avocado and Banana Fruits.

    Science.gov (United States)

    Theologis, A; Laties, G G

    1978-08-01

    The respiration of fresh slices of preclimacteric avocado (Persea americana Mill. var. Hass) and banana (Musa cavendishii var. Valery) fruits is stimulated by cyanide and antimycin. The respiration is sensitive to m-chlorobenzhydroxamic acid in the presence of cyanide but much less so in the presence of antimycin. In the absence of cyanide the contribution of the cyanide-resistant pathway to the coupled preclimacteric respiration is zero. In uncoupled slices, by contrast, the alternate path is engaged and utilized fully in avocado, and extensively in banana. Midclimacteric and peak climacteric slices are also cyanide-resistant and, in the presence of cyanide, sensitive to m-chlorobenzhydroxamic acid. In the absence of uncoupler there is no contribution by the alternate path in either tissue. In uncoupled midclimacteric avocado slices the alternate path is fully engaged. Midclimacteric banana slices, however, do not respond to uncouplers, and the alternate path is not engaged. Avocado and banana slices at the climacteric peak neither respond to uncouplers nor utilize the alternate path in the presence or absence of uncoupler.The maximal capacities of the cytochrome and alternate paths, V(cyt) and V(alt), respectively, have been estimated in slices from preclimacteric and climacteric avocado fruit and found to remain unchanged. The total respiratory capacity in preclimacteric and climacteric slices exceeds the respiratory rise which attends fruit ripening. In banana V(alt) decreases slightly with ripening.The aging of thin preclimacteric avocado slices in moist air results in ripening with an accompanying climacteric rise. In this case the alternate path is fully engaged at the climacteric peak, and the respiration represents the total potential respiratory capacity present in preclimacteric tissue. The respiratory climacteric in intact avocado and banana fruits is cytochrome path-mediated, whereas the respiratory climacteric of ripened thin avocado slices comprises

  10. Bioimpedance Spectroscopy in Detecting Lower-Extremity Lymphedema in Patients With Stage I, Stage II, Stage III, or Stage IV Vulvar Cancer Undergoing Surgery and Lymphadenectomy

    Science.gov (United States)

    2016-02-09

    Lymphedema; Perioperative/Postoperative Complications; Stage IA Vulvar Cancer; Stage IB Vulvar Cancer; Stage II Vulvar Cancer; Stage IIIA Vulvar Cancer; Stage IIIB Vulvar Cancer; Stage IIIC Vulvar Cancer; Stage IVA Vulvar Cancer; Stage IVB Vulvar Cancer

  11. National Survey Results: Retention of Women in Collegiate Aviation

    Science.gov (United States)

    Turney, Mary Ann; Bishop, James C.; Karp, Merrill R.; Niemczyk, Mary; Sitler, Ruth L.; Green, Mavis F.

    2002-01-01

    Since the numbers of women pursuing technical careers in aviation continues to remain very low, a study on retention of women was undertaken by a team of university faculty from Embry Riddle Aeronautical University, Arizona State University, and Kent State University. The study was initiated to discover the factors that influence women once they have already selected an aviation career and to ascertain what could be done to support those women who have demonstrated a serious interest in an aviation career by enrolling in a collegiate aviation program. This paper reports preliminary results of data collected in the first and second years of the study. The data was collected from surveys of 390 college students (195 women and 195 men) majoring in aviation programs in nine colleges and universities, representing widely varied geographic areas and including both two- and four-year institutions. Results revealed significant areas of concern among women in pilot training. When queried about these concerns, differences were evident in the responses of the male and female groups. These differences were expected. However, a surprising finding was that women in early stages of pilot training responded differently from women in more experienced stages, These response differences did not occur among the men surveyed. The results, therefore, suggest that women in experienced stages of training may have gone through an adaptation process and reflect more male-like attitudes about a number of objects, including social issues, confidence, family, and career.

  12. Intervention group as a resource of Occupational Therapy: an experience with menopausal women

    Directory of Open Access Journals (Sweden)

    Soraya Diniz Rosa

    2013-08-01

    Full Text Available Intervention group as a resource of Occupational Therapy is the main theme of this study. Herein we present an experience carried out in two universities in the areas of occupational therapy, pharmacy and medicine, more specifically in the field of gynecology regarding the care of climacteric woman. The first intervention occurred in 2004 with trainees of the occupational therapy course and medical school residents. However, the study was restarted in 2010 with expansion to the human resources and knowledge areas. The methodology was based on the transcripts of the remarks made after each group meeting, which was coordinated by the Occupational Therapy. Results showed that the intervention group process has helped participants in the understanding of this stage of life and has interfered in the changing of habits and attitudes, with great improvement in daily life organization. We concluded that the use of intervention group as a resource of Occupational Therapy and the liaison with other areas are of great importance because they enable the construction of a unique treatment plan for the group, given the contribution from each clinical area.

  13. Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer

    Science.gov (United States)

    2016-02-09

    Stage I Ovarian Cancer; Stage IA Fallopian Tube Cancer; Stage IB Fallopian Tube Cancer; Stage IC Fallopian Tube Cancer; Stage II Ovarian Cancer; Stage IIA Fallopian Tube Cancer; Stage IIB Fallopian Tube Cancer; Stage IIC Fallopian Tube Cancer; Stage III Ovarian Cancer; Stage III Primary Peritoneal Cancer; Stage IIIA Fallopian Tube Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIC Fallopian Tube Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Primary Peritoneal Cancer

  14. Physio-Biochemical Changes in Jujube Fruits(Zizyphus jujuba Mill. cv. Lingwuchangzao) at Mature Stage%灵武长枣果实发育成熟期生理生化变化

    Institute of Scientific and Technical Information of China (English)

    魏天军; 窦云萍

    2008-01-01

    The changes of physiological and biochemical indices in jujube fruits during the late development were investigated from 6-year-old jujube trees (Zizyphus jujuba Mill. cv. Lingwuchangzao). The results showed that the flesh firmness decreased slowly from white-green stage to full-red stage, being significantly related with the developmental maturity of jujube fruits negatively, the correlation coefficient reached -0.980 3**. The contents of ascorbic acid and titratable acid in jujube fruits were significantly related with the developmental process of jujube fruits negatively or positively, the correlation coef-ficients were -0.973 1** and + 0.974 6** respectively. The contents of soluble solids, total sugar, and sucrose increased with jujube ripening, while the relative sweetness of jujube fruits showed the same variation pattern, the correlation coefficients were 0.996 6** , 0.988 0** , and 0.982 8**, respec-tively. Befcre white-green stage during fruit development,the accumulation d moncsaccharide was predom/nant in jujube fruits, following a fast accumula-tion of sucrose, indicating that the main component of sugars is sucrose at the crisp-ripe stage. Furthermore, the starch content of the flesh reached the peak at about thirty percentage of jujube maturity, being 51.54 mg/100 g · FW. The respiratory rates varied between 10 mg/(kg·h) and CO2 26 mg/(kg·h) after fruit turning red and before softening, indicating a non-climacteric respiratory type.

  15. The effect of Hormone Replacement Therapy (HRT in the psychological well-being of menopausal women

    Directory of Open Access Journals (Sweden)

    Eugenia Vlachou

    2013-01-01

    Full Text Available The factors affecting the psychological situation of menopausal women have often been examined in the past. Aim: The purpose of the present study was to examine the psychological disorders that arise in menopausal women receiving Hormone Replacement Therapy (HRT in comparison to those not receiving HRT. Material and Method: The sample of the study included 216 menopausal women, 40-60 years old, divided into two groups and examined twice in a six months period apart. The first group included 100 women receiving HRT for at least three months period, while the second group included116 women not receiving HRT. A demographic inventory, the Greene Climacteric Scale, the Hamilton Anxiety Scale and the CES-D Depression Scale were used. Results: 46.3% of women were taking HRT while 53.7% were not. In the first interview the mean values of the Greene Scale were for the first group 13.21±9.61 and for the second one 25.33±12.25, (p<0.001, while at the second interview the mean values were 9.17±6.93 and 28.65±13.25 respectively, (p<0.001. In the Hamilton scale at the first interview the mean values of the first group were 5.74±8.29 and for the second one 19.28±11.90 (p<0.001, while at the second interview the mean values were 4.43±7.75 and 19.47±11.75 respectively (p<0.001 and were above the threshold of a clinically anxiety syndrome. The mean values of the CES-D in the first interview were 10.33±7.58 in the first group and 11.20±11.22 in the second one (p<0.001, while at the second interview were 8.61±6.25 and 11.82±11.59 respectively (p<0.001. Multiple linear regression analysis demonstrated that the education level interprets 49.4%, 28.4% and 17.1% of the variable, for Greene, Hamilton and CES-D scales respectively (Β=-4.563, p<0.001, Β=-3.012, p=0.005 και Β=-4.175, p<0.001 respectively. Conclusions: HRT seem to provide significant improvement in menopausal psychological symptoms. Further studies are needed in order to clarify relative

  16. Resources for Women's Studies.

    Science.gov (United States)

    Ridinger, Robert B.

    Over 120 bibliographies and other reference sources relevant to women's studies are identified in this annotated listing. Subjects include feminist scholarship, women in management, popular culture, autobiographies, other cultures and countries, history, lesbian women, women's education, the arts, politics, and rape. In addition to author, title,…

  17. Hypertension in postmenopausal women.

    Science.gov (United States)

    Lima, Roberta; Wofford, Marion; Reckelhoff, Jane F

    2012-06-01

    Blood pressure is typically lower in premenopausal women than in men. However, after menopause, the prevalence of hypertension in women is higher than it is in men. Hypertension is a major risk factor for cardiovascular disease in women and men, but cardiovascular disease is the leading cause of death in women. Furthermore, there is evidence that blood pressure may not be as well-controlled in women as in men, despite the fact that most women adhere better to their therapeutic regimens and medications than do men, and have their blood pressures measured more frequently than do men. This review describes possible mechanisms by which blood pressure may be increased in postmenopausal women.

  18. Women's perspectives on illness in being screened for cervical cancer

    DEFF Research Database (Denmark)

    Hounsgaard, Lise; Augustussen, Mikaela; Møller, Helle;

    2013-01-01

    Background In Greenland, the incidence of cervical cancer caused by human papillomavirus (HPV) is 25 per 100,000 women; 2.5 times the Danish rate. In Greenland, the disease is most frequent among women aged 30–40. Systematic screening can identify women with cervical cell changes, which if untrea......Background In Greenland, the incidence of cervical cancer caused by human papillomavirus (HPV) is 25 per 100,000 women; 2.5 times the Danish rate. In Greenland, the disease is most frequent among women aged 30–40. Systematic screening can identify women with cervical cell changes, which...... of analysis: naive reading, structural analysis and critical interpretation. Results These revealed that women were unprepared for screening results showing cervical cell changes, since they had no symptoms. When diagnosed, participants believed that they had early-stage cancer, leading to feelings...

  19. WOMEN AND RUSSIAN MODERNIZATION

    OpenAIRE

    KIREGIAN ELISE

    2015-01-01

    This article analyzes Russian women and their ability to embrace Western educational and business practices following the fall of the Soviet Union. As recently as the 1980s, women managers in Russia were rare. Today, a total of 42 percent of senior management posts in Russia are held by women. Unlike women in Western nations who tend to frame their emerging role in ideological terms, Russian women enrolled in academic programs that gave them valuable skills for the market economy. The paper a...

  20. Women Battle Inequality

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    WTTH women parliamentarians worldwide gathering in Beijing on 15 September 1996, China’s capital city was once again in the spotlight as women gathered to promote gender equality. One year after the Fourth World Conference on Women and the NGO Forum, and one day before the Inter-Parliamentary Union (IPU) held its 96th Conference, 150 women parliamentarians from more than 70 countries gathered in Beijing to attend the 96th Women

  1. Seeking the Holy Grail or the Status of Women in Counseling

    Science.gov (United States)

    Brodsky, Annette M.

    1976-01-01

    Reviews some of the progress in the last 15 years in counseling women. It notes that at this stage of the status of counseling women, there is a need to treat women as individuals who are as different from each other as they are from men. (NG)

  2. Carer Knowledge and Experiences with Menopause in Women with Intellectual Disabilities

    Science.gov (United States)

    Willis, Diane S.; Wishart, Jennifer G.; Muir, Walter J.

    2010-01-01

    Overall life expectancy for women with intellectual disabilities (ID) is now significantly extended, and many will live long enough to experience menopause. Little is known about how carers support women with ID through this important stage in their lives. This study investigated carer knowledge of how menopause affects women with ID under their…

  3. Raising the Bar: An Examination of Career Pathways among Women Working in the Child Welfare System

    Science.gov (United States)

    Williams, Vera L.

    2013-01-01

    In today's society, women who return back to school seeking an advancement within their career is a transition within the lives of women that occurs in various contexts, including the women's ages at the time of their transition, which can define both their expectations and opportunities along their life stages and career paths. In the past, women…

  4. Composers on stage

    DEFF Research Database (Denmark)

    Groth, Sanne Krogh

    A trend on the scene of contemporary music is composers going on stage, performing their pieces themselves. Within a discourse of popular music, this is more the rule than exception, but when it comes to the context of contemporary scored music, the historical and aesthetic context differs......, and something quite different is undergoing. This paper intends to discuss three examples of performances in which the composer’s appearance on stage was an important part of the piece, - both when it came to the role as a performer and as an individual person – as representer and presenter. The paper intends...... 2011 and Fischer-Lichte 2008) Hereby, the role of the composer appearing on stage is discussed from an aesthetic point of view; meanwhile social and political aspects of the phenomenon are also addressed. The three artistic works discussed are Simon Steen-Andersen’s Run Time Error (2009-), Niels...

  5. [Surgical treatment of breast neoplasms in early stages].

    Science.gov (United States)

    Cheshuk, Ie V; Drozdov, V M; Neĭman, A M; Zotov, O S; Zakhartseva, L M; Anikus'ko, M F; Zaĭchuk, V V; Sydorchuk, O I

    2002-01-01

    Analysis of literary data and own investigation results for the modern surgical methods of treatment of mammary gland cancer in early stages was performed. Indexes of patients survival after surgical removal of mammary gland (MG) and quadranthectomy did not differ. Preservation of MG constitutes great social and psycho-emotional significance for women-patients.

  6. Paternal involvement and children's developmental stages in Spain

    NARCIS (Netherlands)

    Gracia, P.

    2012-01-01

    How does fathering change across children's developmental stages and how do these changes vary by educational levels and women's employment? To investigate this, I use the '2003 Spanish Time Use Survey' (N = 2,941) for a sample of heterosexual couples with children of different ages. I differentiate

  7. Staging of prostate cancer.

    Science.gov (United States)

    Cheng, Liang; Montironi, Rodolfo; Bostwick, David G; Lopez-Beltran, Antonio; Berney, Daniel M

    2012-01-01

    Prostatic carcinoma (PCa) is a significant cause of cancer morbidity and mortality worldwide. Accurate staging is critical for prognosis assessment and treatment planning for PCa. Despite the large volume of clinical activity and research, the challenge to define the most appropriate and clinically relevant staging system remains. The pathologically complex and uncertain clinical course of prostate cancer further complicates the design of staging classification and a substaging system suitable for individualized care. This review will focus on recent progress and controversial issues related to prostate cancer staging. The 2010 revision of the American Joint Committee on Cancer/Union Internationale Contre le Cancer (AJCC/UICC) tumour, node and metastasis (TNM) system is the most widely used staging system at this time. Despite general acceptance of the system as a whole, there is controversy and uncertainty about its application, particularly for T2 subclassification. The three-tiered T2 classification system for organ-confined prostate cancer is superfluous, considering the biology and anatomy of PCa. A tumour size-based substaging system may be considered in the future TNM subclassification of pT2 cancer. Lymph node status is one of the most important prognostic factors for prostate cancer. Nevertheless, clinical outcomes in patients with positive lymph nodes are variable. Identification of patients at the greatest risk of systemic progression helps in the selection of appropriate therapy. The data suggest that the inherent aggressiveness of metastatic prostate cancer is closely linked to the tumour volume of lymph node metastasis. We recommend that a future TNM staging system should consider subclassification of node-positive cancer on the basis of nodal cancer volume, using the diameter of the largest nodal metastasis and/or the number of positive nodes.

  8. Women and Politics – The Glass Ceiling

    Directory of Open Access Journals (Sweden)

    Irina Zamfirache

    2010-03-01

    Full Text Available The role of women in modern politics is a subject that needs further insight, considering the growthin number of women that nowadays have relevant political positions on the international stage.There are studies today that emphasize the equality issue and all that is gender role related, but ourinterest is to analyze the women representation in power related positions. Due to the fastmodernization of the political environment and the rapid spreading of the feminist way of thought,several authors took interest in the gender differences in politics. The article follows some keydimensions in understanding the gender-role in politics: the glass ceiling, the role of the media indrawing the image of the woman politician, the gender affinity effect. In the end we would like topoint out the differences for men and women in exploiting the opportunities and securing the positions of power.

  9. The effect of synthetic nursing intervention on breastfeeding self-efficacy among maternal women in different postpartum stages%系统化护理干预对改善产妇母乳喂养自信心效果的研究

    Institute of Scientific and Technical Information of China (English)

    戴红霞

    2014-01-01

    Objective: To explore the effect of synthetic nursing intervention on breastfeeding self-efifcacy and exclusive breastfeeding rate among maternal women in different stages. Methods: The control group (n=148) received routine care with verbal education about breastfeeding. The study group (n=165) received synthetic breastfeeding nursing intervention, which composed of a practical handbook on breastfeeding, breastfeeding skills guiding through face-to-face and one-to-one education at bed-side in hospital, two telephone follow-ups related to breastfeeding at 5 and 11 weeks postpartum. All the participants completed Breastfeeding Self-Efifcacy Scale (BSES) in the hospital, at 6 weeks and 3 months postpartum. Results: At 3 days and 6 weeks postpartum, the mean scores of BSES in the study group were higher than those of the control group (P<0.001). At 3 days, 6 weeks and 3 months postpartum, the exclusive breastfeeding rates in the study group were higher than those of the control group (P<0.05). Conclusion: Synthetic breastfeeding nursing intervention could improve maternal women' breastfeeding self-efifcacy and exclusive breastfeeding rates.%目的:评价系统化护理干预对改善产妇母乳喂养自信心和纯母乳喂养率的效果。方法:选取在广州市3所三级甲等综合性医院妇产科住院分娩的313例产妇为研究对象,按住院顺序分为对照组148例,实验组165例。向对照组实施母乳喂养口头宣教,对实验组应用《实用母乳喂养手册》实施面对面、一对一的哺乳知识与技能指导并于产后5周、11周实施母乳喂养电话指导2次。比较两组产妇在产后3天、6周、3个月时的母乳喂养自信心量表(BSES)评分及纯母乳喂养率。结果:产后3天和6周时,实验组产妇的BSES评分高于对照组(P<0.001);产后3天、6周、3个月时,实验组的纯母乳喂养率高于对照组(P<0.05)。结论:系统化护理干预能显著提高产妇的

  10. Where Do the Women Stand?

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    THE legal status of women in acountry is an important benchmarkof the degree of civilization and progressof that country. In the establishment ofthe People’s Republic of China and itsconstruction of the legal system, the legalframework to protect women’s rights andbenefits is improving. Chinese women’slegal status has witnessed great, profoundchange. The construction of the legal system toprotect women’s legal interests has been athree-tiered process: The first stage was from 1949 to theearly 1950s. At the first meeting of all of

  11. How Is Ovarian Cancer Staged?

    Science.gov (United States)

    ... Cancer Early Detection, Diagnosis, and Staging How Is Ovarian Cancer Staged? Staging is the process of finding out ... Ask Your Doctor About Ovarian Cancer? More In Ovarian Cancer About Ovarian Cancer Causes, Risk Factors, and Prevention ...

  12. Short term follow-up study on emotional disorders and quality of life in women with early stage cervical cancer undergoing gynecologic surgery%早期宫颈癌患者术后情绪障碍及其生命质量的短期追踪调查

    Institute of Scientific and Technical Information of China (English)

    蔡俐琼; 路思思; 王泽华; 刘登华

    2012-01-01

    Objective:To investigate the emotion disorders and quality of life in women with early stage cervical cancer (ESCC) that newly undergoing radical hysterectomy with a follow-up period of 6 months. Methods:One hundred and twenty-five patients with ESCC newly after radical hysterectomy and bilateralpelvic lymph node dissection were accessed with SAS, SDS, CARES-SF and Cantril to investigate the emotion disorders and quality of life. Results:One hundred and eleven patients completed six months of investigation, and the quality of life in the patients newly after operation was in the moderate level. The scores of anxiety and life quality were stable over 6 months,but they were more depressed and had poorer marital and sexual relationship during the follow-up period. Conclusion:Patients with ESCC newly undergoing gynecologic surgery had obvious disorders of anxiety and depression. Medical staff should pay attention to the quality of life of patients,and should make the necessary psychological counseling to help patients coordinate the marital relationship, which will benefit the patients with the common physical and psychological rehabilitation.%目的:调查早期宫颈癌患者术后初期及术后半年焦虑、抑郁情绪和生命质量变化.方法:采用SAS、SDS、CARES-SF、Cantril阶梯量表对125例行宫颈癌根治术后半年内早期宫颈癌患者的情绪特征和生命质量进行了6个月的追踪调查.结果:125例患者中,111例(88.8%)完成了调查,结果显示术后初期患者的生命质量为中等,焦虑情况和生命质量在半年后的得分较稳定,而6个月后的抑郁程度加重,生命质量中的婚姻关系和性关系得分下降.结论:宫颈癌根治术后的早期宫颈癌患者存在明显的焦虑和抑郁情绪,应重视患者生活质量,应对患者进行必要的心理疏导,帮助患者协调婚姻关系,这将有利于宫颈癌患者的身体和心理的共同康复.

  13. Staging of Lung Cancer

    Science.gov (United States)

    ... is important for two reasons. First, staging your lung cancer helps decide which therapy (or therapies) should be used. Second, lung cancer ... 422-6237 http://www.cancer.gov/cancertopics/wyntk/lung/page8 http://www.cancer.gov/cancertopics/pdq/treatment/non- small-cell-lung/Patient/page2 National Lung ...

  14. Stages of Hypopharyngeal Cancer

    Science.gov (United States)

    ... not spread to the larynx (voice box); or cancer has spread to the larynx or esophagus and is more than 4 centimeters; ... a common treatment for all stages of hypopharyngeal cancer. The following surgical ... to remove the larynx (voice box) and part of the pharynx (throat). ...

  15. World Stage Design

    Index Scriptorium Estoniae

    2005-01-01

    12-19. III Torontos rahvusvaheline lavakujunduse, kostüümi ning valgus- ja helikujunduse näitus, mis toimub samaaegselt OISTATi (International Organization of Scenographers, Theatre Architects and Technicians) maailmakongressiga ja USITT (United States Institute for Theatre Technology) üritustega (konverents, Stage Expo). Eestit esindab lavakujunduse kategoorias Lilja Blumenfeld-Luhse

  16. Mixed adenosquamous histology is associated with poorer survival of cervical cancer stage 1b

    DEFF Research Database (Denmark)

    Lauszus, Finn; Tjessem, Ingvild; Al-Far, Hanine M

    2016-01-01

    Background: Evaluation of histopathological factors for women with radical hysterectomy a.m. Okabayashi for cervical cancer in stage 1bwith similar pre- and postoperative treatment Methods: Data on 141 women with cervical cancer stage 1b were revised. The local patient registry, data charts......, while survival was found to be 89 % (83-95 %) and 86 % (79-93 %), respectively. The women’s age at diagnosis showed no association with histology type or survival....

  17. Implicit stage topics

    Directory of Open Access Journals (Sweden)

    Karen Lahousse

    2008-04-01

    Full Text Available Il a souvent été proposé que les éléments spatio-temporels en position initiale de phrase spécifient le cadre de l’événement dénoté par la proposition et ont une interprétation thématique ou topicale. Alors que les topiques spatio-temporels explicites ont souvent été étudiés, Erteschik-Schir (1997, 1999 propose l’idée que les topiques spatio-temporels, ou topiques scéniques (stage topics peuvent aussi être implicites.Dans cet article, nous offrons des arguments en faveur de la notion de topique scénique implicite. Nous montrons qu’un certain nombre de cas d’inversion nominale en français, une configuration syntaxique qui est favorisée par la présence d’un topique scénique explicite, s’expliquent par la présence d’un topique scénique implicite. Le fait que les topiques scéniques implicites interagissent avec la structure syntaxique de la même façon que les topiques scéniques explicites constitue un argument empirique en faveur de leur existence.It has often been proposed that sentence-initial spatio-temporal elements specify the frame in which the whole proposition takes place and are topical (i.e. thematic. Whereas considerable attention has been paid to explicit spatio-temporal topics, Erteschik-Shir (1997, 1999 argues that spatio-temporal topics, or stage topics, can also be implicit.In this article we provide evidence in favour of the notion of implicit stage topic. We show that a certain number of nominal inversion cases in French, a syntactic configuration which is triggered by the presence of an explicit stage topic, are explained by the presence of an implicit stage topic. The fact that implicit stage topics interact with syntactic structure the same way explicit stage topics do constitutes a strong empirical argument in favour of their existence.

  18. Multi-stage cleaning plant

    Energy Technology Data Exchange (ETDEWEB)

    Kullendorff, A.; Wikner, J.

    1980-12-09

    A cleaning plant positioned within an annular fluidized bed combustion chamber is divided into a plurality of separate cleaning stages, wherein a first stage is located adjacent the fluidized bed and additional stages are arranged within the first stage. Each stage comprises a plurality of separate cleaning devices which act in parallel, while cleaning devices of different stages act in series to remove debris from the combustion gases that exit from the fluidized bed combustion chamber.

  19. Violence against women.

    Science.gov (United States)

    Keizire, J

    1995-01-01

    This article discusses the prevalence of violence against women in Uganda. The incidence of violence against women has been increasing despite efforts by law enforcement orders. In the broadest sense, violence against women is any violation of a woman's personhood, mental or physical integrity or freedom of movement. Violence against women is considered as an obstacle to the achievement of the objectives of equality, development and peace. Moreover, the act violates and impairs women's rights and fundamental freedoms. The low social and economic status of women can be both a cause and a consequence of violence against women. Physical, sexual and psychological violence occurring in the family, including battering, sexual abuse of female children, dowry-related violence, marital rape, female genital mutilation and other traditional practices harmful to women, limit the ability to make choices on women's lives.

  20. Assistência à mulher climatérica: novos paradigmas Atención a la mujer climatérica: nuevos paradigmas Assistance to the climacteric woman: new paradigms

    Directory of Open Access Journals (Sweden)

    Dino Roberto Soares De Lorenzi

    2009-04-01

    Full Text Available O envelhecimento populacional é uma realidade demográfica brasileira. Como conseqüência, espera-se, nos próximos anos, um aumento progressivo na procura dos serviços de saúde por mulheres com queixas relacionadas ao climatério. Paralelamente, a assistência ao climatério tem passado por uma modificação de paradigmas, impondo aos profissionais de saúde uma mudança de atitude. Reconhece-se que o climatério é influenciado tanto por fatores biológicos, como por fatores psicossociais e culturais, cujo conhecimento é fundamental para uma assistência mais qualificada e humanizada. Este artigo propõe refletir sobre as mudanças de paradigmas na assistência ao climatério, destacando a multidisciplinaridade e interdisciplinaridade, no sentido acolher melhor essa parcela da população e proporcionar-lhe um cuidado integral e individualizado, aproximando o saber da sensibilidade, voltado a uma melhor qualidade vida.Envejecimiento poblacional es una realidad demográfica brazilian. Consecuentementese espera un aumento progresivo de la búsqueda en los servicios de salud del país por mujeres con quejas relacionadas al climaterio. La asistencia al climaterio ha pasado por un cambio de paradigmas que han impuesto a los profesionales de la salud. El climaterio es influenciado por factores biológicos, factores psicosociales y culturales, cuyo conocimiento es fundamental para la planificación de una asistencia. Artículo se propone reflexionar sobre los cambios de paradigmas, el abordaje multidisciplinario e interdisciplinario, en el sentido de recibir mejor esta parcela de la población y proporcionarle un cuidado integral e individualizado, aproximando el saber de la sensibilidad, y el tener como objetivo a una mejor calidad de vida.Population aging is a demographic reality for Brazil. Consequently, in the next years it is expected a progressive increase in seeking health care services in the country by women with complaints related to

  1. Albanian women in physics

    Science.gov (United States)

    Deda, Antoneta; Alushllari, Mirela; Mico, Silvana

    2015-12-01

    In this report, presented at the 5th IUPAP International Conference on Women in Physics, we describe the status of women physicists in Albania and offer some statistical data illustrating the present situation. Undergraduate physics enrollment by girls is high and stable, more women are receiving financial support for doctoral studies, women are well represented in recent academic promotions, and recently women scientists have been appointed to several leadership positions. However, both women and men are challenged by the overall low levels of funding for research and by issues of availability and affordability of child care.

  2. Women's rights to health.

    Science.gov (United States)

    1997-08-01

    Women's rights and health are threatened by cultural, religious, and social biases against women that create barriers in women's ability to access health information, education, and services. The fact that women's basic human rights include a right to health has been incorporated in international rights covenants, but violations occur in the form of 1) direct state actions, such as coercive abortion; 2) failure of states to meet health needs; 3) discrimination that denies health care to specific groups; and 4) failure of states to protect women from violence, child marriage, female infanticide, and other forms of health- and life-threatening discrimination. In order to improve this situation, a basic set of indicators must be developed to monitor implementation of agreements to protect women. Health professionals must continue to incorporate women's rights into the ethics or charters of health practices, to improve service to women, and to increase governmental advocacy on behalf of women. Governments must acknowledge the benefits of applying a rights approach to women's health status and must develop plans to implement recommendations arising from international conferences on women's rights. Women-centered nongovernmental organizations must create a clear framework on women's rights to health and develop advocacy and networking strategies.

  3. Staging Sociotechnical Spaces

    DEFF Research Database (Denmark)

    Clausen, Christian; Yoshinaka, Yutaka

    2007-01-01

    The management of innovation and product development is increasingly facing complex challenges of staging design processes across heterogeneous organisational spaces, with multiple actor-concerns and sources of knowledge. This paper addresses how insights from the Actor-Network Theory and political...... process theory may contribute to a reflexive understanding of design as the staging of socio-technical relations and processes cutting across boundaries of diverse organisational, political and knowledge domains. This idea is pursued through the notion of ‘socio-technical spaces’. Socio-technical space...... of product development. The concept of socio-technical spaces is further illustrated through actual examples from industry dealing with early conceptualisation in product development and the role played by management concepts in the configuration of spaces....

  4. Calibration of Nanopositioning Stages

    Directory of Open Access Journals (Sweden)

    Ning Tan

    2015-12-01

    Full Text Available Accuracy is one of the most important criteria for the performance evaluation of micro- and nanorobots or systems. Nanopositioning stages are used to achieve the high positioning resolution and accuracy for a wide and growing scope of applications. However, their positioning accuracy and repeatability are not well known and difficult to guarantee, which induces many drawbacks for many applications. For example, in the mechanical characterisation of biological samples, it is difficult to perform several cycles in a repeatable way so as not to induce negative influences on the study. It also prevents one from controlling accurately a tool with respect to a sample without adding additional sensors for closed loop control. This paper aims at quantifying the positioning repeatability and accuracy based on the ISO 9283:1998 standard, and analyzing factors influencing positioning accuracy onto a case study of 1-DoF (Degree-of-Freedom nanopositioning stage. The influence of thermal drift is notably quantified. Performances improvement of the nanopositioning stage are then investigated through robot calibration (i.e., open-loop approach. Two models (static and adaptive models are proposed to compensate for both geometric errors and thermal drift. Validation experiments are conducted over a long period (several days showing that the accuracy of the stage is improved from typical micrometer range to 400 nm using the static model and even down to 100 nm using the adaptive model. In addition, we extend the 1-DoF calibration to multi-DoF with a case study of a 2-DoF nanopositioning robot. Results demonstrate that the model efficiently improved the 2D accuracy from 1400 nm to 200 nm.

  5. Women and Alcohol

    Science.gov (United States)

    ... turn JavaScript on. Feature: Rethinking Drinking Women and Alcohol Past Issues / Spring 2014 Table of Contents Women react differently than men to alcohol and face higher risks from it. Pound for ...

  6. Women in Academic Medicine.

    Science.gov (United States)

    Thibault, George E

    2016-08-01

    More than a decade ago, women achieved parity with men in the number of matriculants to medical school, nearly one-third of the faculty of medical schools were women, and there were some women deans and department chairs. These trends were promising, but today there are still significant differences in pay, academic rank, and leadership positions for women compared with men in academic medicine. Though there has been progress in many areas, the progress is too slow to achieve previously recommended goals, such as 50% women department chairs by 2025 and 50% women deans by 2030.The author points to the findings presented in the articles from the Research Partnership on Women in Biomedical Careers in this issue, as well as research being published elsewhere, as an evidence base for the ongoing discussion of gender equity in academic medicine. More attention to culture and the working environment will be needed to achieve true parity for women in academic medical careers.

  7. Women's Career Development Patterns.

    Science.gov (United States)

    Schreiber, Pamela J.

    1998-01-01

    Women's career development is characterized by balance of work and family, career interruptions, and diverse career paths. Alternative work arrangements such as flexible schedules, telecommuting, and entrepreneurial opportunities may offer women more options for work. (SK)

  8. Alternatives for Women

    Science.gov (United States)

    Alberti, Jean M.

    1975-01-01

    This article summarized the perspective of this issue by recognizing the validity of the issues being raised by the women's rights movement and also recognizing that the "liberation of women" means the liberation of men. (Author/RK)

  9. Women and Diabetes

    Medline Plus

    Full Text Available ... during pregnancy. Diabetes and Pregnancy (CDC) Diverse Women in Clinical Trials Campaign Clinical trials can help doctors ... ages, races, ethnic backgrounds, and health conditions participating in clinical trials. Visit the Women in Clinical Trials ...

  10. College Women's Health

    Science.gov (United States)

    ... the College Women's Social Media Kit! College Women's Social Media Toolkit Use the Social Media Toolkit to ... Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products

  11. Substance Use in Women

    Science.gov (United States)

    ... trigger women's substance use or other mental health disorders. Women who use certain substances may be more likely to have panic attacks, anxiety, or depression. Substance Use While Pregnant and Breastfeeding ...

  12. Osteoporosis and Hispanic Women

    Science.gov (United States)

    ... not supported by your browser. Home Osteoporosis Women Osteoporosis and Hispanic Women Publication available in: PDF (54 ... Are Available? Resources For Your Information What Is Osteoporosis? Osteoporosis is a condition in which the bones ...

  13. Women of Jino Nationality

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    The dress of the Jino nationality differs greafiy from village to village. The upper photo shows the women of Xinyuan Village, Mengwang Township, with the photo on the right featuring women from Jiamazhai Village, Jino Township.

  14. How Women Changed History

    Institute of Scientific and Technical Information of China (English)

    Vivienne; Gill; 袁爱萍

    2003-01-01

    Men sometimes say, "We are better and cleverer than women. Women never invent things. We do. " It is true that men have invented a lot of useful things: the alphabet, machines, rockets, and guns, too.

  15. Identifying the Barriers to Women's Agency in Domestic Violence: The Tensions between Women's Personal Experiences and Systemic Responses

    Directory of Open Access Journals (Sweden)

    Jo Aldridge

    2013-04-01

    Full Text Available Despite advances in knowledge and understanding about the impacts of domestic violence on women's lives, global research on violence against women shows there is a need for research that not only places women centre stage in research praxis, but also that involves them more collaboratively in genuine dialogue about their experiences, including their agentic stances. This is especially the case for marginalised and socially excluded women victims of domestic violence, such as those who are not known or do not present to services and who survive abusive relationships alone or with little outside support. Evidence from two studies reported here—secondary analysis of women with severe and enduring mental health problems and a collaborative narrative project with unsupported women victims of domestic violence—suggest that women's capacity for agency are compromised by a number of critical factors, and that these are also reflected in the tensions between micro–macro analyses and understanding of the impact of domestic violence on women. This article considers the barriers to women's agency from the women's perspective and in the context of broader, systemic dynamics, including the denial or obscuring of abuse by governments and states and the consequences of stringent fiscal retrenchment that put women at increased risk of domestic violence.

  16. Heart Disease in Women

    Science.gov (United States)

    ... United States, 1 in 4 women dies from heart disease. The most common cause of heart disease in both men and women is narrowing or ... It's the major reason people have heart attacks. Heart diseases that affect women more than men include Coronary ...

  17. Women in Technical Education.

    Science.gov (United States)

    Ellis, Mary L.

    Perhaps the most significant challenge of the 1970's will be the effect the women's rights movement will have on the nation's established institutions and the extent to which the nation responds to the call of women for equal opportunities. Social pressures and expectations have been, until recently, such that women simply have not opted for jobs…

  18. Women in Information Technology

    Science.gov (United States)

    Wentling, Rose Mary; Thomas, Steven P.

    2004-01-01

    There is a major concern about the drop of young women entering Computer Science degree programs and a drop in the participation of women in these information technology occupations. In all levels of educational institutions across the nation, girls and women remain under-represented in computer and information science studies and subsequently,…

  19. Women and Diabetes

    Medline Plus

    Full Text Available ... Skip to common links HHS U.S. Department of Health and Human Services U.S. Food and Drug Administration ... Consumers Consumer Information by Audience For Women Women's Health Topics Women and Diabetes Share Tweet Linkedin Pin ...

  20. Workplace Safety and Women

    Centers for Disease Control (CDC) Podcasts

    2009-05-11

    This women's health podcast focuses on four important issues for women at work: job stress, work schedules, reproductive health, and workplace violence.  Created: 5/11/2009 by Office of Women's Health (OWH) and National Institute for Occupational Safety and Health (NIOSH).   Date Released: 5/11/2009.

  1. Longevity of Women Superintendents

    Science.gov (United States)

    Sethna, Kim C.

    2014-01-01

    Public schools are facing a leadership crisis regarding the lack of women superintendents in the United States. Although, historically, women have dominated the positions of classroom teachers and outnumbered men in receiving administrative leadership certificates, there is a disproportion in the number of men and women superintendents leading the…

  2. Women of California.

    Science.gov (United States)

    Gray, Harry

    This publication points out the achievements of women who contributed to the development and history of California from the 16th century, when the Spanish Conquistadores moved westward into the San Francisco Bay area, to the gold rush of 1848, and during the following period when women helped stabilize society on the rugged frontier. Women not…

  3. Four Women Bank Directors

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    FOUR of the five directors of state banks in Beihai City in Guangxi Zhuang Autonomous Region are women. These women show that women are no longer only able to manage family finance, but they are able to take charge of the important responsibility for state finance. The mayor of Beihai City calls them the city’s outstanding financial affairs managers.

  4. Primary staging of prostate cancer

    Energy Technology Data Exchange (ETDEWEB)

    Jager, G.J. [Dept. of Radiology, Univ. Hospital, Nijmegen (Netherlands); Barentz, J.O. [Dept. of Radiology, Univ. Hospital, Nijmegen (Netherlands); Ruijter, E.T.G. [Dept. of Urology, Univ. Hospital, Nijmegen (Netherlands)]|[Dept. of Pathology, Univ. Hospital, Nijmegen (Netherlands); Rosette, J.J.M.C.H. de la [Dept. of Urology, Univ. Hospital, Nijmegen (Netherlands); Oosterhof, G.O.N. [Dept. of Urology, Univ. Hospital, Nijmegen (Netherlands)

    1996-04-01

    Staging prostate cancer is a systematic classification of the extent of disease based on clinical and pathological criteria. Despite general acceptance of the TNM staging system, a lot of controversy and uncertainty with respect to staging still exists. This paper gives an overview of differnt staging modalities and emphasizes the need for incorporation of prognostic factors, such as tumour grade and volume, in the staging system. (orig.)

  5. Initial Staging of Hodgkin’s Disease

    Science.gov (United States)

    Chiaravalloti, Agostino; Danieli, Roberta; Caracciolo, Cristiana Ragano; Travascio, Laura; Cantonetti, Maria; Gallamini, Andrea; Guazzaroni, Manlio; Orlacchio, Antonio; Simonetti, Giovanni; Schillaci, Orazio

    2014-01-01

    Abstract The objective of this study was to compare the diagnostic accuracy of positron emission tomography/low-dose computed tomography (PET/ldCT) versus the same technique implemented by contrast-enhanced computed tomography (ceCT) in staging Hodgkin’s disease (HD). Forty patients (18 men and 22 women, mean age 30 ± 9.6) with biopsy-proven HD underwent a PET/ldCT study for initial staging including an unenhanced low-dose computed tomography for attenuation correction with positron emission tomography acquisition and a ceCT, performed at the end of the PET/ldCT scan, in the same exam session. A detailed datasheet was generated for illness locations for separate imaging modality comparison and then merged in order to compare the separate imaging method results (PET/ldCT and ceCT) versus merged results positron emission tomography/contrast-enhanced computed tomography (PET/ceCT). The nodal and extranodal lesions detected by each technique were then compared with follow-up data that served as the reference standard. No significant differences were found at staging between PET/ldCT and PET/ceCT in our series. One hundred and eighty four stations of nodal involvement have been found with no differences in both modalities. Extranodal involvement was identified in 26 sites by PET/ldCT and in 28 by PET/ceCT. We did not find significant differences concerning the stage (Ann Arbor). Our study shows a good concordance and conjunction between PET/ldCT and ceCT in both nodal and extranodal sites in the initial staging of HD, suggesting that PET/ldCT could suffice in most of these patients. PMID:25121354

  6. Effects of the Xuzao Gengping Granule to the quality of life of Yinxu Neizao female climacteric hypertension%虚燥更平颗粒对阴虚内燥证女性高血压病(围绝经期)患者生活质量的影响

    Institute of Scientific and Technical Information of China (English)

    林雪; 任玉汝; 马丽; 周丽萍

    2012-01-01

    目的:通过观察虚燥更平颗粒对女性高血压病(围绝经期)生活质量的影响,从而为中医治疗女性高血压病(围绝经期)提供临床依据.方法:收集2008年7月至2009年10月新疆医科大学附属中医医院高血压科就诊的阴虚内燥证女性高血压病(围绝经期)患者96例(病房59例、门诊37例),随机分为治疗组与对照组,两组在西药基础上,分别给予虚燥更平颗粒及模拟剂,疗程为8周,分别于治疗前与治疗后2、4、8周各进行1次生活质量评分、中医证候评分,并做统计分析.结果:①治疗组生理状态、躯体化症状、性功能失调、睡眠状态、生气或活力、焦虑、压抑等状态积分均较对照组增高(P<0.05),而强迫状态积分无统计学差异.②治疗组烘热汗出、烦躁易怒、眩晕头昏、口干舌燥、失眠心悸、健忘、手或足心热、忧郁寡欢、腰膝酸痛、手或足麻木等症候积分均较对照组降低(P<0.05),而耳鸣症候积分无统计学差异;中医证候疗效总有效率高于对照组(P<0.05).结论:应用虚燥更平颗粒治疗女性高血压病(围绝经期)患者,可以提高生活质量,同时能有效改善其临床症状.%Objective: To observe the effect of the Xuzao Gengping Granule on the quality of females' life and all the females with climacteric hypertension, providing the clinical basis for the traditional Chinese medicine to cure female hypertensive disease (menopause). Methods: 96 patients with female climacteric hypertension were choose from hypertension outpatient clinics and ward in Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region between July 2008 and October 2009, the Yinxu Neizao group was divided into treatment group and control group. To judge the score of the quality of life and TCM syndrome respectively before and after treatment. Results: CD Compared with the control group, the score of physiological status, somatization symptoms, sexual

  7. Endoscopic ultrasound for staging of colonic cancer proximal to the rectum

    DEFF Research Database (Denmark)

    Malmstrøm, Marie Louise; Săftoiu, Adrian; Vilmann, Peter

    2016-01-01

    proximal to the rectum. PATIENTS AND METHODS: Men and women with colonic adenocarcinomas were included in the study. EUS staging was compared to histopathology as the gold standard. Outcome measures were T- and N-staging accuracies. Articles were searched in PubMed, Web of Science, The Cochrane Library...

  8. Asymptomatic bacteriuria in postmenopausal women with diabetes mellitus

    Directory of Open Access Journals (Sweden)

    George Kasyan

    2013-05-01

    Full Text Available Introduction. An evaluation of efficacy of the management of urinary tract infections by using local forms of Estriol in postmenopausal women with type II diabetes and asymptomatic bacteriuria.Material and methods. The study was conducted in two stages. The first stage: a prospective cross–sectional study to identify patients with asymptomatic bacteriuria. During this stage, 414 postmenopausal women with type II diabetes, but without clinical symptoms of urinary tract infection, were investigated. In the second stage, women with asymptomatic bacteriuria (87 women were randomized to two groups: the first group was the main group receiving 0.5 mg of Estriol as a vaginal cream, the second group was the control group. The study lasted 12 months.Results. After 12 months of the study, asymptomatic bacteriuria was revealed in 19.4% of women in the group 1 and 68.4% of women in the group 2 (р <0.001, and symptomatic urinary tract infection in 8.3% of women in the group 1 and 18.4% of women in the group 2 (р <0.001. There was no connection revealed between asymptomatic bacteriuria and НвА1с. Using Estriol in group 1 led to an increase in VHI, the appearance of lactobacilli in the vaginal smear, and the decrease of symptom frequency in atrophic vaginitis. In group 2, there were no significant changes revealed.Conclusions. Usage of local forms of Estriol effectively prevents and decreases the frequency of asymptomatic bacteriuria and urinary tract infection in postmenopausal women suffering with diabetesmellitus.

  9. Feminism and Black Women's Studies.

    Science.gov (United States)

    Hooks, Bell

    1989-01-01

    Women's studies programs have largely ignored Black women. Until Black women's studies courses are developed, feminist scholarship on Black women will not advance, and the contributions of Black women to women's rights movements and African American literature and scholarship may be neglected. (DM)

  10. Women in Latin American History.

    Science.gov (United States)

    Lavrin, Asuncion

    1981-01-01

    Presents a bibliography and suggests a number of topics around which a college level history course on Latin American women could be organized. Course topics include migration of women, definition of sex roles, legal status of women, women's work and society, feminism, politics, religion, women and the family, and women's education and…

  11. 男性更年期综合征患者性腺轴功能变化及其与代谢综合征的关系的动物性实验研究%Animal experimental study of gonadal axis function changes in patients with male climacteric syndrome and the relationship with metabolic syndrome

    Institute of Scientific and Technical Information of China (English)

    牛晓振; 郑军华; 耿江; 车建平; 王光春; 夏盛强; 王波; 彭波

    2015-01-01

    目的:通过动物实验研究男性更年期综合征与性腺轴、以及代谢综合征的关系.方法:以6月龄雄性大鼠饲养至30月龄复制自然衰老、代谢综合征及补充雄激素的动物模型.通过对各组大鼠12、18、24、30月龄性激素、性激素受体水平检测,睾丸切片分析,研究年龄、激素水平及代谢综合症的相关性.结果:随着月龄的增加,正常饲养大鼠T、FSH及LH逐渐下降,睾丸组织病理呈退行性变化.睾酮饲喂组不同月龄大鼠血清T、FSH、LH水平持续维持较高水平,但睾丸雄激素受体水平仍出现显著下降.结论:单纯补充雄激素能提高性腺轴激素水平,但不能逆转睾丸雄性激素受体水平的下降,不足以治疗男性更年期综合征,须同时提高雄性激素受体水平.%Objective:To study of the relationship among male climacteric syndrome, gonadal axis, and metabolic syndrome in animal experiments.Methods: hTe 6-month-old male rats were reared to 30-month-old to copy natural aging, metabolic syndrome and androgen supplement models. At 12, 18, 24, 30 months old sex hormones, hormone receptor levels, testis slices were tested and analyzed.Results: With the increase of age, T, FSH and LH of normal feeding group decreased, and testicular pathology showed degenerative changes. Serum T, FSH, LH levels of Testosterone fed groups continue to maintain a high level, but testicular androgen levels of RNA and protein levels were signiifcant decreased.Conclusion: Supplement of androgen can maintain gonadal axis, but cannot change the decline of testicular androgen receptor. Androgen supplement treatment cannot cure male climacteric syndrome. It is also essential to increase the male hormone receptor levels.

  12. Lymphadenectomy in locally advanced cervical cancer study (LiLACS): Phase III clinical trial comparing surgical with radiologic staging in patients with stages IB2-IVA cervical cancer.

    Science.gov (United States)

    Frumovitz, Michael; Querleu, Denis; Gil-Moreno, Antonio; Morice, Philippe; Jhingran, Anuja; Munsell, Mark F; Macapinlac, Homer A; Leblanc, Eric; Martinez, Alejandra; Ramirez, Pedro T

    2014-01-01

    Radiation treatment planning for women with locally advanced cervical cancer (stages IB2-IVA) is often based on positron emission tomography (PET). PET, however, has poor sensitivity in detecting metastases in aortocaval nodes. We have initiated a study with the objective of determining whether pre-therapeutic laparoscopic surgical staging followed by tailored chemoradiation improves survival as compared with PET/computed tomography (CT) radiologic staging alone followed by chemoradiation. This international, multicenter phase III trial will enroll 600 women with stages IB2-IVA cervical cancer and PET/CT findings showing fluorodeoxyglucose-avid pelvic nodes and fluorodeoxyglucose-negative para-aortic nodes. Eligible patients will be randomized to undergo either pelvic radiotherapy with chemotherapy (standard-of-care arm) or surgical staging via a minimally invasive extraperitoneal approach followed by tailored radiotherapy with chemotherapy (experimental arm). The primary end point is overall survival. Secondary end points are disease-free survival, short- and long-term morbidity with pre-therapeutic surgical staging, and determination of anatomic locations of metastatic para-aortic nodes in relationship to the inferior mesenteric artery. We believe this study will show that tailored chemoradiation after pre-therapeutic surgical staging improves survival as compared with chemoradiation based on PET/CT in women with stages IB2-IVA cervical cancer.

  13. Women residents, women physicians and medicine's future.

    Science.gov (United States)

    Serrano, Karen

    2007-08-01

    The number of women in medicine has increased dramatically in the last few decades, and women now represent half of all incoming medical students. Yet residency training still resembles the historical model when there were few women in medicine. This article reviews the issues facing women in residency today. Data suggest that the experience of female residents is more negative than that of males. Unique challenges facing female residents include the existence of gender bias and sexual harassment, a scarcity of female mentors in leadership positions, and work/family conflicts. Further research is needed to understand the experience of female residents and to identify barriers that hinder their optimal professional and personal development. Structural and cultural changes to residency programs are needed to better accommodate the needs of female trainees.

  14. Women scientists joining Rokkasho women to sciences

    Energy Technology Data Exchange (ETDEWEB)

    Aratani, Michi [Office of Regional Collaboration, Institute for Environmental Sciences, Rokkasho, Aomori (Japan); Sasagawa, Sumiko

    1999-09-01

    Women scientists generally play a great role in the public acceptance (PA) for the national policy of atomic energy developing in Japan. The reason may be that, when a woman scientist stands in the presence of women audience, she will be ready to be accepted by them as a person with the same gender, emotion and thought to themselves. A case of interchange between the Rokkasho women and the women scientists either resident at the nuclear site of Rokkasho or staying for a short time at Rokkasho by invitation has been described from the viewpoint of PA for the national policy of atomic energy developing, and more fundamentally, for promotion of science education. (author)

  15. Examples of geoscientists women in France

    Science.gov (United States)

    Mognard-Campbel, N.; Cazenave, A.

    2004-12-01

    Although the presence of women in sciences has been increasing in the past few decades in Europe, it remains incredibly low at the top levels. Recent statistics from the European Commission indicate that now women represent 50 percent of first degree students in many countries. However, the proportion of women at each stage of the scientific career decreases almost linearly, reaching less than 10 percent at the highest level jobs. From my own experience, I don't think that this results from sexism nor discrimination. Rather, I think that this is a result of complex cultural factors making women subconsciously persuaded that top level jobs are destined to male scientists only. Many women scientists drop the idea of playing a role at high-level research, considering it as a way of exerting power (a matter reserved to men). Others give up the possibility of combining childcare and high level commitments in research. And too many (married women) still find only natural to sacrifice their own scientific ambitions to the benefit of their spouse's career. Examples of personal experiences in the French research system are presented. We discuss some choices of prioritizing scientific productivity and expertise against hierarchical responsibilities and of keeping a satisfactory balance between family demand and research involvement. This is somewhat facilitated by the French system, which provides substantial support to women's work (nurseries, recreation centers during school holidays, etc.). As a conclusion, we think that the most promising way of increasing the number of women at top levels in research is through education and mentality evolution.

  16. Fertility and contraception in end-stage renal disease.

    Science.gov (United States)

    Schmidt, R J; Holley, J L

    1998-01-01

    The hormonal aberrations that occur with end-stage renal disease (ESRD) are presented in this review in relation to fertility and conception among women on dialysis. The imbalance in gonadotropin production in dialysis-dependent men and women is characterized by elevations in luteinizing hormone (LH). In women dialysis patients, the normal estradiol-stimulated LH surge does not occur, resulting in anovulation. In men dialysis patients spermatogenesis is impaired, and low testosterone levels cause elevated LH. Infertility in those with ESRD is a culmination of many factors, including impotence and loss of libido, anovulation, and an altered hormonal milieu. Despite these inhibitors of conception, women on dialysis can conceive; pregnancy has been reported in 1% to 7% of women on dialysis in survey studies. The influence of dialysis mode (hemodialysis v peritoneal dialysis), recombinant human erythropoietin (EPO), and dialysis adequacy on the likelihood of conception among patients of either sex on dialysis is unknown. Reduced sexual activity and interest has consistently been reported in the ESRD population. The reasons for this are complex and likely involve the effects of comorbid illnesses, overall health status, body image factors, and hormonal alterations. Nephrologists rarely discuss conception and contraception with their women dialysis patients. Greater attention to these issues is needed.

  17. Magnetic resonance imaging in the staging of cervical cancer

    Energy Technology Data Exchange (ETDEWEB)

    Camisao, Claudia C. [Hospital Sao Lucas, Rio de Janeiro, RJ (Brazil)]. E-mail: ccamisao@inca.gov.br; Brenna, Sylvia M.F. [Hospital Maternidade Leonor Mendes de Barros, Sao Paulo, SP (Brazil); Lombardelli, Karen V.P. [Hospital do Cancer (HCII), Rio de Janeiro, RJ (Brazil); Djahjah, Maria Celia R. [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil). Faculdade de Medicina. Dept. de Radiologia; Zeferino, Luiz Carlos [Universidade Estadual de Campinas (UNICAMP), Campinas, SP (Brazil). Faculdade de Ciencias Medicas. Dept. de Ginecologia

    2007-05-15

    Cervical cancer is the worldwide leading cause of cancer-related death of women, especially in developing countries. The International Federation of Gynecology and Obstetrics recommends staging during surgery, however, surgical-pathologic staging would not be feasible in cases of more advanced cancers. Generally, in these cases, the staging is performed by means of clinical and gynecological examination and basic imaging studies. However, such an approach fails to demonstrate the actual extent of the disease, and does not include significant prognostic factors such as tumor volume, stromal invasion and lymph node involvement. Magnetic resonance imaging has increasingly been utilized in cervical cancer staging, since at early stages of the disease its performance may be compared to intraoperative findings and, at advanced stages, it shows to be superior to the clinical evaluation. Additionally, magnetic resonance imaging presents an excellent imaging resolution for the different densities of pelvic structures, does not require ionizing radiation, is comfortable for the patient, improves de staging, allowing the early detection of recurrence and the identification of reliable prognostic factors which contribute to the therapeutic decision making process and results prediction with an excellent cost-effectiveness. The present article is aimed at reviewing the most significant aspects of magnetic resonance imaging in the cervical cancer staging. (author)

  18. Staging interrail mobilities

    DEFF Research Database (Denmark)

    Jensen, Martin Trandberg; Gyimóthy, Szilvia; Jensen, Ole B.

    2016-01-01

    studies of rail travel, by exploring how interrail travel is embedded in, and (im)mobilised by socio-material environments and institutional design decisions. More precisely, it explores the affordances of three objects that shape interrail mobility: the interrail pass, the RailPlanner application......This article applies the multiscalar ‘staging mobilities’ framework from the emergent subfield of mobilities design to analyse an enduring European rail travel phenomenon, interrail. This discussion extends and contributes to tourism mobilities research. Second, the article enriches previous...... and seat reservations. To reach these aims, the research design intertwines multi-sited ethnography, netnography, survey and interviews. The conclusion offers theoretical reflections pertaining to the role of mobilities designs and methodical hybrids in tourism mobilities research....

  19. Successful Pregnancy Using the NxStage Home Hemodialysis System

    Directory of Open Access Journals (Sweden)

    Yasmin Brahmbhatt

    2016-01-01

    Full Text Available Pregnancy in the setting of the uremic milieu of renal disease has a lower success rate than in the normal population and is a rare event. While intensified renal replacement therapy (RRT during pregnancy can lead to improved outcomes, most studies have focused on nocturnal hemodialysis as the main RRT in pregnancy. Although thousands of patients use the home NxStage System One short daily hemodialysis (SDHD machine in the United States, pregnancy outcomes with this therapy are unknown. The NxStage System One uses low-volume dialysate and hence small and middle molecule clearance may differ compared to conventional therapies and affect pregnancy outcomes. We report a case of a successful conception and pregnancy using the home NxStage system. The NxStage system may provide an alternative to the more routinely used NHD or standard SDHD therapies for women of childbearing age.

  20. CalCOFI Egg Stages

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Egg morphological developmental stage for eggs of selected species captured in CalCOFI icthyoplankton nets. Sequential developmental stages are described by Moser...

  1. Second-stage labor: how long is too long?

    Science.gov (United States)

    Leveno, Kenneth J; Nelson, David B; McIntire, Donald D

    2016-04-01

    The management of labor has come under increased scrutiny due to the rapid escalation of cesarean delivery in the United States. A workshop of the Society for Maternal-Fetal Medicine, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the American Congress of Obstetricians and Gynecologists was convened to address the rising cesarean delivery rates and one of their recommendations was that the accepted upper limit of the second stage of labor should be increased to ≥4 hours in nulliparous women with epidural analgesia and to ≥3 hours in parous women with epidural. This led to the inaugural Obstetric Care Consensus series document, "Safe Prevention of the Primary Cesarean Delivery," wherein the workshop recommendations on second-stage labor were promulgated nationally. The result is that the now acceptable maximum length of the second stage of labor exceeds the obstetric precepts that have been in use for >50 years. In this Clinical Opinion, we review the evidence on infant safety, vis-à-vis length of the second stage of labor. Our examination of the evidence begins at the outset of the 20th century and culminates in the very recent (2014) recommendation to abandon the long accepted obstetric paradigm that second-stage labor >3 hours in nulliparous women with labor epidural is unsafe for the unborn infant. We conclude that the currently available evidence fails to support the Obstetric Care Consensus position that longer second-stage labor is safe for the unborn infant. Indeed, the evidence suggests quite the opposite. We suggest that when infant safety is at stake the evidence should be robust before a new clinical road is taken. The evidence is not robust.

  2. Staged urethroplasty: indications and techniques.

    Science.gov (United States)

    Secrest, Charles L

    2002-05-01

    There is still a place for staged urethroplasty. There are some indications for staged urethral reconstruction such as strictures associated with chronic inflammation, fistula, false passage, urethral stones, urethral diverticula, abscess, failed prior repair, complicated hypospadias, severe trauma, neurologic diseases, extensive BXO strictures and long strictures. Staging a urethroplasty should not be considered a step backwards rather instead we should learn from experience and realize there are some patients who are too complex to reconstruct in a single stage.

  3. Long-term psychological distress in women at risk for hereditary breast cancer adhering to regular surveillance: a risk profile

    NARCIS (Netherlands)

    Heijer, M. den; Seynaeve, C.; Vanheusden, K.; Timman, R.; Duivenvoorden, H.J.; Tilanus-Linthorst, M.; Menke-Pluijmers, M.B.; Tibben, A.

    2013-01-01

    BACKGROUND: Some women at risk for hereditary breast cancer are at increased risk of psychological distress. In order to tailor support for individual women, the availability of a tool enabling the identification of psychologically vulnerable women at an early stage is warranted. The objectives of t

  4. RESILIENCE IN WOMEN WHO EXPERIENCED VIOLENCE - REVIEW OF SCIENTIFIC PRODUCTION

    OpenAIRE

    Rodrigues, Raquel Fonseca; Instituto Fernandes Figueira - IFF/FIOCRUZ; Carinhanha, Joana Iabrudi; Instituto de Psiquiatria da UFRJ; penna, lucia helena garcia; faculdade de enfermagem da uerj

    2010-01-01

    OBJECTIVE: To contribute to the deepening of discussions about resilience, adding nursing and women who experienced violence, as the resilience can be developed at any stage of a person's life nowadays and resilience has been investigated primarily by psychology and focuses on understanding and enhance resilience in children and adolescents. METHOD: A literature review of scientific literature on resilience in women who experienced violence in the area of public health. RESULTS: We found 5 ar...

  5. Management of HIV infected pregnant women in Chonburi Hospital.

    Science.gov (United States)

    Pinchun, P

    1994-04-01

    This study on birth control methods used, and HIV infection protection of the HIV infected pregnant women in the obstetrics-gynecology department of Chonburi Hospital from 1 January 1990 to 31 December 1993 revealed that there were 27 HIV infected women with less than 24 weeks gestational age, using birth control methods as such 12 women (44.44%) had tubal resection after abortion, 8 women (29.62%) oral contraceptive pills, 5 women (15.51%) injectable contraception, and 2 women (7.40%) norplants. The 106 HIV infected women with more than 24 weeks gestational age were allowed to deliver. The birth control methods were as follows: 19 women (17.92%) tubal resection, 38 women (35.84%) oral contraceptive pills, 49 women (46.22%) injectable contraception. They were all encouraged to use a condom while having sexual intercourse. Only 40 women of this group are still seen in the follow-up clinic and all are found to be healthy, the birth control is effective and HIV infection is in the early stage. The new born babies were not allowed to be breast fed and were followed-up periodically to 18 months old. Twenty five babies received HIV blood test; 7 babies (28%) were found to be HIV infected. The birth control and HIV infection protection used in this study demonstrate no adverse effects on the disease, and the unexpected problems of these women, as well as the health personnel concerned are reduced both economically and socially. This study provides the guidelines of good care for HIV infected pregnant women.

  6. Health screening - women - over age 65

    Science.gov (United States)

    Health maintenance visit - women - over age 65; Physical exam - women - over age 65; Yearly exam - women - over age 65; Checkup - women - over age 65; Women's health - over age 65; Preventive care exam - women - over ...

  7. Gestational Diabetes and Women

    Centers for Disease Control (CDC) Podcasts

    2009-05-12

    This women's health podcast focuses on gestational diabetes (GDM) to help educate women who may have been diagnosed with GDM now or in the past. GDM is a condition that can lead to pregnancy complications.  Created: 5/12/2009 by Office of Women’s Health (OWH) and National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 5/12/2009.

  8. Chinese Women Laborers

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    FOR the last three years I have been working on two big projects about women around the world. One is Mothers of the World, and the other one is Working Women of the World. So I travel to different parts of the world to meet Women and photograph them. I knew from the start that I would be able to see China only very superficially, because there was no way I could spend more than two to three weeks there. I therefore

  9. Organization Champions Menopausal Women

    Institute of Scientific and Technical Information of China (English)

    JANE SHAW

    1994-01-01

    CURRENTLY, the ageing of the population has created problems for a developing China. Jiangsu is one of the provinces that has encountered these problems, where the average lifespan for women is 73. Women aged 40 to 55 who are going through menopause account for about 8 percent of Jiangsu’s total population. Whether this group is able to live a healthy life during menopause or not decides whether the women are healthy and happy and influences the rest of society.

  10. Chlamydia and Women

    Centers for Disease Control (CDC) Podcasts

    2009-04-02

    This women's health podcast focuses on chlamydia, its severe health consequences for women if left untreated, and the importance of annual chlamydia screening.  Created: 4/2/2009 by Office of Women’s Health (OWH) and National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP).   Date Released: 4/2/2009.

  11. Obesity and Women

    Centers for Disease Control (CDC) Podcasts

    2009-05-11

    This women's health podcast focuses on obesity in women and girls. It discusses obesity-related health risks and includes tips to help achieve and maintain a healthy weight.  Created: 5/11/2009 by Office of Women’s Health (OWH) and National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 5/11/2009.

  12. WOMEN IN FAMILY BUSINESS

    OpenAIRE

    Anshu,

    2012-01-01

    The role of women in family businesses is explored in the paper. Although recognized as generally very important players, the role of women is often defined as invisible in business decision-making, supportive in men’s traditional business domains and only rarelyadequately recognized and rewarded. The paper explores possible differences in the views of men and women who manage small family firms. Their attitudes opposing the traditional business roles ofwomen, different views on managerial, o...

  13. Os sentidos atribuídos à voz por mulheres após a menopausa The meanings attributed to the voice by menopause women

    Directory of Open Access Journals (Sweden)

    Maria Aparecida Miranda de Paula Machado

    2005-04-01

    Full Text Available OBJETIVO: Analisar os sentidos atribuídos à voz por mulheres após a menopausa. MÉTODOS: Foram coletados dados de 148 mulheres nos prontuários médicos, entre fevereiro de 2000 e outubro de 2001, no Programa da Saúde da Mulher no Climatério, do ambulatório de ginecologia de um hospital na cidade de Curitiba, Estado do Paraná. Dentre a população total foram selecionadas intencionalmente 30 mulheres entre 48 e 59 anos, que não se consideravam profissionais da voz, no mínimo há 12 meses em amenorréia, e que foram entrevistadas com um roteiro temático, constituído de questões semi-estruturadas. Cada entrevista foi gravada e transcrita. A descrição, análise e interpretação foram fundamentadas pelas representações sociais, por meio do discurso do sujeito coletivo, com aproximações à hermenêutica-dialética. RESULTADOS: Os 27 discursos coletivos estruturados denotaram o relacionamento da voz às características biológicas, psicológicas e aspectos sociais do cotidiano, com a identificação de mudanças vocais no decorrer da vida. CONCLUSÕES: Foi possível observar representações sociais de natureza comunicacional e funcional, que salientaram a voz como elemento de constituição da identidade pessoal, concebida na pertinência social. A pesquisa sugere novas investigações fundamentadas nas ciências sociais, simultâneas aos estudos epidemiológicos, e a necessidade de se refletir sobre o processo de terapêutica vocal aplicado sobre uma laringe mais vulnerável, além de priorizar uma proposta de assistência integral à mulher no climatério, com enfoque sobre a saúde da voz.OBJECTIVE: To analyze the meanings attributed to the voice by menopausal women. METHODS: Data were collected from 148 medical records of women seen in the Climacteric Women Health Program of the Irmandade Santa Casa de Misericórdia Gynecology Outpatient Clinic in Curitiba, Brazil, between February 2000 and October 2001. Of them, 30 women aged

  14. Older Women's Development: A Comparison of Women in Their 60s and 80s on a Measure of Erikson's Developmental Tasks.

    Science.gov (United States)

    Norman, Suzanne M.; McCluskey-Fawcett, Kathleen; Ashcraft, Lisa

    2002-01-01

    Compares women from two ages groups in order to understand their development across the life span. Measures of Psychosocial Development, which assesses Erikson's developmental stages, were administered to 41 women in 2 cohorts (ages 60-70, ages 80-90). Age group differences in the resolution of Erikson's identity and trust developmental tasks were…

  15. Rediscovering Women Mathematicians.

    Science.gov (United States)

    Rappaport, Karen D.

    The lives and mathematical contributions of seven famous women mathematicians are presented. They are: Hypatia, Agnesi, Sophie Germain, Mary Sommerville, Augusta Lovelace, Sofya Kovalevsky, and Emmy Noether. (MP)

  16. Venous thromboembolism in women

    DEFF Research Database (Denmark)

    Group, ESHRE Capri Workshop; Skouby, Sven Olaf

    2013-01-01

    is associated with an inherited thrombophilia in men and women. Changes in the coagulation system and in the risk of clinical VTE in women also occur during pregnancy, with the use of reproductive hormones and as a consequence of ovarian stimulation when hyperstimulation syndrome and conception occur together...... therapy (HRT) increases the VTE risk 2- to 4-fold. There is a synergistic effect between thrombophilia and the various reproductive risks. Prevention of VTE during pregnancy should be offered to women with specific risk factors. In women who are at high risk, CHC and HRT should be avoided. CONCLUSIONS...

  17. Women in service uniforms

    Directory of Open Access Journals (Sweden)

    Hanna Karaszewska

    2012-12-01

    Full Text Available The article discusses the problems of women who work in the uniformed services with the particular emphasis on the performing of the occupation of the prison service. It presents the legal issues relating to equal treatment of men and women in the workplace, formal factors influencing their employment, the status of women in prison, and the problems of their conducting in the professional role. The article also presents the results of research conducted in Poland and all over the world, on the functioning of women in prison and their relations with officers of the Prison Service, as well as with inmates.

  18. Spring of women?

    Directory of Open Access Journals (Sweden)

    Mónica Castillo

    2012-12-01

    Full Text Available Terms such as “Islamic feminism” and “women’s movement” refer to those social movements of women that seek to assert their rights in Islamic societies. This brief study focuses on theses social movements of women and will presentan overview of the role and participation of women in the Arab Spring by examining news, events, press articles and opinions in order to contextualize the participation of women and feminists in the Arab Spring from a perspective of the social networking phenomenon as apparent drivers of the revolution.

  19. Womens Business Center

    Data.gov (United States)

    Small Business Administration — Women's Business Centers (WBCs) represent a national network of nearly 100 educational centers throughout the United States and its territories, which are designed...

  20. Science on stage

    CERN Multimedia

    2005-01-01

    During the opening ceremony, the audience was dazzled by a juggling show involving dramatic light effects. They also took away with them a teacher's sheet explaining some of the scientific concepts involved in juggling. Science teachers can sometimes be quite humorous when it comes to explaining serious matters, as those who took part in the 'Science on Stage' festival held at CERN from 21 to 25 November were able to see for themselves. The 500 or so participants from 27 different countries, mostly science teachers but also some university lecturers, science outreach specialists and students, had the opportunity to share their experience of the teaching of science. They also attended presentations and shows, took part in workshops and visited a fair with stands offering ideas on how to make school science lessons more appealing. The festival, organised by the EIROforum (a partnership between CERN, EFDA, ESA, ESO, EMBL, ESRF and ILL), marked the end of two years of projects for the promotion of science in vir...

  1. Depressão e ansiedade em mulheres climatéricas: fatores associados Depression and anxiety in menopausal women: associated factors

    Directory of Open Access Journals (Sweden)

    Álvaro Fernando Polisseni

    2009-01-01

    ção significativa entre a presença de sintomas climatéricos de intensidade moderada e o aparecimento dessas alterações do humor (pPURPOSE: to determine the prevalence of depression and anxiety in climacteric women and the probable factors responsible for its occurrence. METHODS: a transversal study that has selected 93 women attended at a climacteric outpatient clinic, from May 2006 to August 2007. Inclusion criteria were: women from 40 to 65 years old who agreed with participating in the project. Exclusion criteria: patients in hormonal therapy, hormone-therapy by implant, DIUs and depo injections in the preceding six months, endocrinopathies leading to menstrual irregularities, hepatopathies, thrombopathies, use of drugs which interfere in the menstrual cycle, anxiolytics and antidepressants (as their use indicates previous diagnosis of mood disorders, hysterectomy, oophorectomy, cancer or psychiatric disease, and patients who had been submitted to radio or chemotherapy. During the interview, four questionnaires were applied: Anamnesis, containing socio-demographic, clinical and living habits data; Blatt-Kupperman's Menopausal Index for climacteric syndrome diagnosis; Anxiety sub-scale of the Hospital Anxiety and Depression scale (HADS-A for anxiety diagnosis; and Beck's Depression Inventory for the diagnosis of depression. Descriptive and correlation analysis among the variables, χ2 and Hosmer-Lemeshow tests were performed using the Statistica Software program, version 6. RESULTS: the average depression prevalence among the patients was 36.8%, while that of anxiety was 53.7%. There was no significant difference between the prevalence of depression and anxiety in the three phases of climacterium. There was a significant relationship between the presence of moderate climacteric symptoms and the presence of mood alterations (p<0.001. Depression was more frequent in women with anxiety (OR=4.2 and insomnia (OR=4.9, having a job being a protection factor (OR=0.2. Risk factors

  2. Cervical cancer: screening, diagnosis and staging.

    Science.gov (United States)

    Tsikouras, Panagiotis; Zervoudis, Stefanos; Manav, Bachar; Tomara, Eirini; Iatrakis, George; Romanidis, Constantinos; Bothou, Anastasia; Galazios, George

    2016-01-01

    Purpose: Despite the widespread screening programs, cervical cancer remains the third most common cancer in developing countries. Based on the implementation of cervical screening programs with the referred adoption of improved screening methods in cervical cytology with the knowledge of the important role of the human papilloma virus (HPV) it's incidence is decreased in the developed world. Even if cervical HPV infection is incredibly common, cervical cancer is relatively rare. Depending on the rarity of invasive disease and the improvement of detection of pre-cancerous lesions due to the participation in screening programs, the goal of screening is to detect the cervical lesions early in order to be treated before cancer is developed. In populations with many preventive screening programs, a decrease in cervical cancer mortality of 50-75% is mentioned over the past 50 years. The preventive examination of vagina and cervix smear, Pap test, and the HPV DNA test are remarkable diagnostic tools according to the American Cancer Association guidelines, in the investigation of asymptomatic women and in the follow up of women after the treatment of pre-invasive cervical cancer. The treatment of cervical cancer is based on the FIGO 2009 cervical cancer staging.

  3. Bevacizumab, Cisplatin, Radiation Therapy, and Fluorouracil in Treating Patients With Stage IIB, Stage III, Stage IVA, or Stage IVB Nasopharyngeal Cancer

    Science.gov (United States)

    2014-04-21

    Stage II Squamous Cell Carcinoma of the Nasopharynx; Stage III Lymphoepithelioma of the Nasopharynx; Stage III Squamous Cell Carcinoma of the Nasopharynx; Stage IV Lymphoepithelioma of the Nasopharynx; Stage IV Squamous Cell Carcinoma of the Nasopharynx

  4. Sexual function in women receiving maintenance dialysis.

    Science.gov (United States)

    Seethala, Srikanth; Hess, Rachel; Bossola, Maurizio; Unruh, Mark L; Weisbord, Steven D

    2010-01-01

    While substantial attention has been paid to the issue of sexual dysfunction in men on chronic dialysis, less is known about this problem in women with end-stage renal disease. We sought to assess sexual dysfunction in women on chronic dialysis and determine whether patients discuss this problem with their providers and receive treatment. We prospectively enrolled women receiving chronic hemodialysis or peritoneal dialysis in Pittsburgh, PA. We asked patients to complete the 19-item Female Sexual Function Index (FSFI) to assess sexual function and a 5-item survey that assessed whether patients had discussed sexual dysfunction with their providers and/or received treatment for this problem in the past. We enrolled 66 patients; 59 (89%) on hemodialysis and 7 (11%) on peritoneal dialysis. All patients completed the FSFI, of whom 53 (80%) had FSFI scores <26.55, consistent with the presence of sexual dysfunction. Of 37 patients who were married or residing with a significant other, 27 (73%) had sexual dysfunction. Among 24 participants who reported having been sexually active over the previous 4 weeks, 11 (46%) had sexual dysfunction. Only 21% of patients with sexual dysfunction had discussed this problem with their gynecologist, renal or primary provider, and 3 (6%) reported having received treatment. Sexual dysfunction is common in women on dialysis, even among patients who are married or residing with a significant other and those who are sexually active. However, few women discuss this issue with their providers or receive treatment.

  5. Insomnia in women approaching menopause: Beyond perception.

    Science.gov (United States)

    Baker, Fiona C; Willoughby, Adrian R; Sassoon, Stephanie A; Colrain, Ian M; de Zambotti, Massimiliano

    2015-10-01

    The menopausal transition is marked by increased prevalence in disturbed sleep and insomnia, present in 40-60% of women, but evidence for a physiological basis for their sleep complaints is lacking. We aimed to quantify sleep disturbance and the underlying contribution of objective hot flashes in 72 women (age range: 43-57 years) who had (38 women), compared to those who had not (34 women), developed clinical insomnia in association with the menopausal transition. Sleep quality was assessed with two weeks of sleep diaries and one laboratory polysomnographic (PSG) recording. In multiple regression models controlling for menopausal transition stage, menstrual cycle phase, depression symptoms, and presence of objective hot flashes, a diagnosis of insomnia predicted PSG-measured total sleep time (p insomnia had, on average, 43.5 min less PSG-measured sleep time (p insomnia reported more WASO (p = 0.002), more night-to-night variability in WASO (p insomnia in the approach to menopause have a measurable sleep deficit, with almost 50% of the sample having less than 6h of sleep. Compromised sleep that develops in the context of the menopausal transition should be addressed, taking into account unique aspects of menopause like hot flashes, to avoid the known negative health consequences associated with insufficient sleep and insomnia in midlife women.

  6. Sexual functioning and vaginal changes after radical vaginal trachelectomy in early stage cervical cancer patients: a longitudinal study

    DEFF Research Database (Denmark)

    Froeding, LP; Ottesen, C; Rung-Hansen, H

    2014-01-01

    Radical vaginal trachelectomy (RVT) offers low complication rate, good survival, and possibility for future childbearing for young women with early stage cervical cancer. However, the literature on quality of life (QOL) and sexual functioning in patients undergoing RVT is scarce....

  7. Do stage of disease, comorbidity or access to treatment explain socioeconomic differences in survival after ovarian cancer?

    DEFF Research Database (Denmark)

    Ibfelt, Else Helene; Dalton, Susanne Oksbjerg; Høgdall, Claus

    2015-01-01

    educated women. After adjustment for comorbid conditions, cancer stage, tumour histology, operation status and lifestyle factors, socioeconomic differences in survival persisted. CONCLUSIONS: Socioeconomic disparities in survival after ovarian cancer were to some extent, but not fully explained...

  8. Diagnosis: a liminal state for women living with lupus.

    Science.gov (United States)

    Mendelson, Cindy

    2009-05-01

    Women with systemic lupus erythematosus (SLE or lupus) often experience a protracted diagnostic period in which their symptoms are treated as medically unexplained. Although they know they are ill, their symptoms have not been validated as indicative of disease by a health care professional. Consequently, the diagnostic period can be viewed as liminal, the middle stage in the rites of passage and what Turner (1969/1997) has labeled "betwixt and between." Drawing on the analysis of narratives solicited from 23 women recruited from online lupus support groups, I explore the gendered nature of diagnosis for women with lupus using van Gennep's (1960) rites of passage as a conceptual framework.

  9. Arab women's breast cancer screening practices: a literature review.

    Science.gov (United States)

    Donnelly, Tam Truong; Khater, Al-Hareth Al; Al-Bader, Salha Bujassoum; Al Kuwari, Mohammed Ghaith; Al-Meer, Nabila; Malik, Mariam; Singh, Rajvir; Jong, Floor Christie-de

    2013-01-01

    Breast cancer incidence and mortality rates are increasing in the Arab world and the involved women are often diagnosed at advanced stages of breast cancer. This literature review explores factors influencing Arab women's breast cancer screening behavior. Searched databases were: Medline, PubMed, Cochrane Database of Systematic Reviews, CINAHL Plus, Google Scholar, Index Medicus for WHO Eastern Mediterranean, and Asian Pacific Journal of Cancer Prevention. Breast cancer screening participation rates are low. Screening programs are opportunistic and relatively new to the region. Knowledge amongst women and health care providers, professional recommendation, socio-demographic factors, cultural traditions, beliefs, religious, social support, accessibility and perceived effectiveness of screening influence screening behavior.

  10. Rural Women's Land Rights and Interests Merit Close Attention

    Institute of Scientific and Technical Information of China (English)

    MO WENXIU

    2007-01-01

    @@ At the present stage in China,land is rural women's most basic means of production and life and most important material guarantee. Land contracting and related rights and interests have a direct bearing on the interests of rural women. Guaranteeing rural women's land contracting right and related economic rights and interests is of immediate significance for safeguarding their rights and interests and mobilizing them in active participation in the construction of a new socialist countryside. It will also have a farreaching significance for promoting social fairness and justice and building a socialist harmonious society.

  11. Analysis of Career Burnout of Middle-aged Career Women%中年职业女性的职业倦怠之分析

    Institute of Scientific and Technical Information of China (English)

    林莉

    2012-01-01

    中年职业女性工作压力大、烦恼多,她们在这段时期面临家庭的压力,如子女升学就业、父母的赡养照料;要面临工作的压力,如知识的更新、评职晋级、人际关系冲突;还要面临生理的变化,如更年期综合症的冲击等。这些方面造成她们更早地进入职业倦怠期。文章着重分析了中年职业女性职业倦怠的生理和心理特征,探寻通过社会、组织、家庭和自身等途径,帮助中年职业女性干预职业倦怠,促进中年女性的职业心理健康。%Middle-aged career women are confronted with pressures and vexation during their work life. They face all kinds of pressures in this period, household pressure such as their children's education and job-hunting, supporting and taking care of their parents; pressure from their own work such as the updating of knowledge, promotion in their position and interpersonal relationship problems; physiological and mental pressure such as climacteric syndrome. All these factors force them to enter into career burnout early. This paper focuses on the analysis of the physiological and psychological features of middle-aged career women with career burnout and seeks ways to help middle-aged career women to solve the problem of career burnout and promote the health in their professional psychology through social, organizational, family and personal means.

  12. Breast cancer stage at diagnosis: is travel time important?

    Science.gov (United States)

    Henry, Kevin A; Boscoe, Francis P; Johnson, Christopher J; Goldberg, Daniel W; Sherman, Recinda; Cockburn, Myles

    2011-12-01

    Recent studies have produced inconsistent results in their examination of the potential association between proximity to healthcare or mammography facilities and breast cancer stage at diagnosis. Using a multistate dataset, we re-examine this issue by investigating whether travel time to a patient's diagnosing facility or nearest mammography facility impacts breast cancer stage at diagnosis. We studied 161,619 women 40 years and older diagnosed with invasive breast cancer from ten state population based cancer registries in the United States. For each woman, we calculated travel time to their diagnosing facility and nearest mammography facility. Logistic multilevel models of late versus early stage were fitted, and odds ratios were calculated for travel times, controlling for age, race/ethnicity, census tract poverty, rural/urban residence, health insurance, and state random effects. Seventy-six percent of women in the study lived less than 20 min from their diagnosing facility, and 93 percent lived less than 20 min from the nearest mammography facility. Late stage at diagnosis was not associated with increasing travel time to diagnosing facility or nearest mammography facility. Diagnosis age under 50, Hispanic and Non-Hispanic Black race/ethnicity, high census tract poverty, and no health insurance were all significantly associated with late stage at diagnosis. Travel time to diagnosing facility or nearest mammography facility was not a determinant of late stage of breast cancer at diagnosis, and better geographic proximity did not assure more favorable stage distributions. Other factors beyond geographic proximity that can affect access should be evaluated more closely, including facility capacity, insurance acceptance, public transportation, and travel costs.

  13. Investigation and Analysis on Physical Fitness of Old and Middle-aged Women in Shanghai%对上海市中老年妇女体质状况的调查与分析

    Institute of Scientific and Technical Information of China (English)

    庄洁; 王人卫; 陈及治; 谭晓缨; 郭仕达; 蔡斌; 段子才; 高勇

    2001-01-01

    By the methods of morphological and functional measurements, the authors made an investigation into the physical fitness of 463 women aged from 40 to 70. It has been found from the measuring results that the rate of body fat and BMI indices in this age group inclined to rise, their systolic pressure and pulse pressure tend to increase, their TC has a tendency to go up and the TC among the women in early senility and senility is significantly different from those who are in climacteric. The relevant analysis on above indices has revealed that body fat of each group is positively interrelated with BMI index; HDL is positively related to TC. But the internal pulse pressure and GLu in the climacteric group are positively related to BMI index while HDL is negatively interrelated with BMI and HDL negatively with GLu. At the same time, the rate of TC/HDL is positively related to GLu in the groups of early senility and senility.%采用形态、机能等测试方法,对上海市463名40~70岁中老年妇女的体质状况进行调查。测试结果发现,随着年龄增长,该人群体脂率与BMI指数呈上升趋势,收缩压及脉压有逐渐增加趋势,血总胆固醇(TC)有升高趋势,其中老年前期、老年期均较中年更年期有显著性差异。各指标相关分析显示:各组体脂率与BMI指数呈显著正相关;高密度脂蛋白(HDL)与TC呈正相关。其中,中年更年期组内脉压、血糖(GLu)与BMI指数呈正相关,HDL与BMI指数呈负相关,HDL与GLu呈负相关;老年前期、老年期组TC/HDL比值与GLu呈正相关。

  14. Circumventing problems of accessibility to rural muslim women.

    Science.gov (United States)

    Safai, M

    1979-01-01

    A study of rural women's work was undertaken in 1977 by the Center for National Spatial Planning of the Plan and Budget Organization of Iran. Within the dehestan (smallest administrative unit) of Amlash, a region near the Caspian seacoast, 2-stage probability sampling procedures were used: villages were divided into 4 population strata, then 1 village selected randomly from each 1. A 20% random sample of women was selected. The women were interviewed in the field or working at home. Most of the men in the villages were quick to give credit to their wives and seemed eager for their wives to be interviewed. The rural women were willing and able to discuss the work they do; they know the steps and the technology involved and provide exact answers. With the exception of the 1st stage of rice production, women do considerable work. The assumption that women's work can be measured proved to be accurate. Generally, it was found that little impact has been made on the traditional division of labor. The tasks that have been known to be done primarily by women, including transplanting, weeding, and tea picking, are still done by women. The experience in Amlash demonstrates that random sampling is possible at the village level and within villages; that men need not feel threatened by a female research team; that it is possible to obtain reliable information from women about what they do and how much work is theirs; and that the women are willing and eager to discuss the work they do.

  15. Women and Advertising

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    The Platform for Action adopted at the United Nations Fourth World Conference On Women acknowledges the media’s role in eliminating sexual discrimination and promoting women’s development.It lists women and media as one of the ten fields that require strategic targeting and action.

  16. Women and Heart Disease

    Institute of Scientific and Technical Information of China (English)

    邹国如

    2005-01-01

    Heart disease is the leading killer of Americans. But it kills more women than men. The American Heart Association says heart disease and other cardiovascular (心血管的) disorders kill about five hundred thousand women a year. That is more than the next seven causes of death combined.

  17. Cancer and Women

    Science.gov (United States)

    ... I J K L M N O P Q R S T U V W X Y Z # ... CDC.gov . Cancer Home Kinds of Cancer Bladder Breast Cervical Colorectal (Colon) Head and Neck Kidney Leukemia ... Anxiety and Depression Medicine Use Among Cancer Survivors Breast Cancer Rates Among Black Women and White Women ...

  18. Shattering women's glass ceiling

    OpenAIRE

    Camilleri Podesta, Marie Therese; Duca, Edward

    2013-01-01

    The role of women in academia has always greatly interested me. Several years ago, when I was asked to become Gender Issues Committee chairperson at the University of Malta, I readily accepted. http://www.um.edu.mt/think/shattering-womens-glass-ceiling/

  19. Androgenetic alopecia in women.

    Science.gov (United States)

    Price, Vera H

    2003-06-01

    Androgenetic alopecia (AGA), also known in women as female pattern hair loss, is caused by androgens in genetically susceptible women and men. The thinning begins between ages 12 and 40 years, the inheritance pattern is polygenic, and the incidence is the same as in men. In susceptible hair follicles, dihydrotestosterone binds to the androgen receptor, and the hormone-receptor complex activates the genes responsible for the gradual transformation of large terminal follicles to miniaturized follicles. Both young women and young men with AGA have higher levels of 5alpha reductase and androgen receptor in frontal hair follicles compared to occipital follicles. At the same time, young women have much higher levels of cytochrome p-450 aromatase in frontal follicles than men who have minimal aromatase, and women have even higher aromatase levels in occipital follicles. The diagnosis of AGA in women is supported by early age of onset, the pattern of increased thinning over the frontal/parietal scalp with greater density over the occipital scalp, retention of the frontal hairline, and the presence of miniaturized hairs. Most women with AGA have normal menses and pregnancies. Extensive hormonal testing is usually not needed unless symptoms and signs of androgen excess are present such as hirsutism, severe unresponsive cystic acne, virilization, or galactorrhea. Topical minoxidil solution is the only drug available for promoting hair growth in women with AGA. Efficacy has been shown in double-blind studies using hair counts and hair weight.

  20. Professional Women and Marriage.

    Science.gov (United States)

    Allen, Suzanne M.; Kalish, Richard A.

    1984-01-01

    Explored the phenomenon of late marriage in 41 highly educated professional women. Compared with normative marriers, the late-marrying women had higher career goals, a more egalitarian role structure in marriage, and were more accepting of premarital sex and cohabitation. Factors associated with family backgrounds were identified. (JAC)

  1. Women and Computer Science.

    Science.gov (United States)

    Breene, L. Anne

    1992-01-01

    Discusses issues concerning women in computer science education, and in the workplace, and sex bias in the computer science curriculum. Concludes that computing environment has not improved for women over last 20 years. Warns that, although number of white males entering college is declining, need for scientists and engineers is not. (NB)

  2. Entrepreneurs: Women and Minorities.

    Science.gov (United States)

    Akers, Lilialyce

    A program was designed to meet the needs of Kentucky women who wished to supplement their incomes by producing articles in their homes for sale. Its three-phase objective was to identify women who already had knitting skills and train them to produce a finished product; to provide basic knowledge about how to run a small business; and to provide…

  3. Oral Health and Women

    Centers for Disease Control (CDC) Podcasts

    2009-05-12

    This women's health podcast focuses on the importance of maintaining good oral health during pregnancy.  Created: 5/12/2009 by Office of Women’s Health (OWH) and National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 5/12/2009.

  4. African Women Writing Resistance

    Institute of Scientific and Technical Information of China (English)

    Jennifer Browdy de Hernandez; Pauline Dongala; Omotayo; Jolaosho; Anne Serafin

    2011-01-01

    AFRICAN Women Writing Resistance is the first transnational anthology to focus on women's strategies of resistance to the challenges they face in Africa today.The anthology brings together personal narratives,testimony,interviews,short stories,poetry,performance scripts,folktales and lyrics.

  5. Women and Law

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    WOMEN’S rights concern the world over. Even though China has a different legal tradition and social system, participants from the Beijing Sino-British Women and Law Symposium discovered that both Chinese and foreign scholars could reach agreement and understanding on many issues. Enacting Laws for Women Professor Yang Dawen, from the

  6. Chinese Women in Politics

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    According to international research only when the percentage of women with decision-making power reaches 30 percent can their effect on policy making be seen. In 1994, women accounted for an average of 5.7 percent of state cabinet seats throughout the world. Authoritative thinking is that in the past decade almost no progress was made in realizing the 30

  7. Women's Rights Network (WRN).

    Science.gov (United States)

    Slote, K; Cuthbert, C

    1997-02-01

    The Massachusetts-based Women's Rights Network (WRN) was founded in 1995 in response to the need to develop collaborative, crosscultural, and international strategies to eliminate domestic violence. The WRN initiated meetings with local advocates to identify the most pressing issues facing the US battered women's movement and then began to contact advocates for battered women throughout the world. To date, the WRN offers a resource center documenting strategies used around the world to end domestic violence, gives workshops and presentations to increase public education and awareness about domestic violence, organizes international strategy sessions between women's advocates in Massachusetts and those in other countries, facilitates one-on-one partnerships between groups for battered women in Massachusetts and sister organizations in other countries, and participates in the annual "16 Days of Activism Against Gender Violence." The WRN also plans to publish a biannual journal.

  8. Injuries in women's basketball.

    Science.gov (United States)

    Trojian, Thomas H; Ragle, Rosemary B

    2008-03-01

    Women's basketball has changed over time. It is a faster paced game than it was 30 years ago. Greatplayers, like Anne Meyers,who was the first, and only, woman to be signed to an NBA contract, would agree today's game is different. The game is played mostly "below the rim" but with players like Candice Parker, Sylvia Fowles and Maya Moore able to dunk the ball, the game is still changing. The one thing that remains constant in basketball, especially women's basketball, is injury. The majority of injuries in women's basketball are similar to those in men's basketball. Studies at the high school and college level show similar injury rates between women and men. ACL injuries are one exception, with female athletes having atwo to four times higher rate ofACL injuries. In this article, we review the common injuries in women's basketball. We discuss treatment issues and possible preventive measures.

  9. Staged membrane oxidation reactor system

    Science.gov (United States)

    Repasky, John Michael; Carolan, Michael Francis; Stein, VanEric Edward; Chen, Christopher Ming-Poh

    2013-04-16

    Ion transport membrane oxidation system comprising (a) two or more membrane oxidation stages, each stage comprising a reactant zone, an oxidant zone, one or more ion transport membranes separating the reactant zone from the oxidant zone, a reactant gas inlet region, a reactant gas outlet region, an oxidant gas inlet region, and an oxidant gas outlet region; (b) an interstage reactant gas flow path disposed between each pair of membrane oxidation stages and adapted to place the reactant gas outlet region of a first stage of the pair in flow communication with the reactant gas inlet region of a second stage of the pair; and (c) one or more reactant interstage feed gas lines, each line being in flow communication with any interstage reactant gas flow path or with the reactant zone of any membrane oxidation stage receiving interstage reactant gas.

  10. Staged Repository Development Programmes

    Energy Technology Data Exchange (ETDEWEB)

    Isaacs, T

    2003-10-01

    Programs to manage and ultimately dispose of high-level radioactive wastes are unique from scientific and technological as well as socio-political aspects. From a scientific and technological perspective, high-level radioactive wastes remain potentially hazardous for geological time periods-many millennia-and scientific and technological programs must be put in place that result in a system that provides high confidence that the wastes will be isolated from the accessible environment for these many thousands of years. Of course, ''proof'' in the classical sense is not possible at the outset, since the performance of the system can only be known with assurance, if ever, after the waste has been emplaced for those geological time periods. Adding to this challenge, many uncertainties exist in both the natural and engineered systems that are intended to isolate the wastes, and some of the uncertainties will remain regardless of the time and expense in attempting to characterize the system and assess its performance. What was perhaps underappreciated in the early days of waste management and repository program development were the unique and intense reactions that the institutional, political, and public bodies would have to repository program development, particularly in programs attempting to identify and then select sites for characterization, design, licensing, and ultimate development. Reactions in most nations were strong, focused, unrelenting, and often successful in hindering, derailing, and even stopping national repository programs. The reasons for such reactions and the measures to successfully respond to them are still evolving and continue to be the focus of many national program and political leaders. Adaptive Staging suggests an approach to repository program development that reflects the unique challenges associated with the disposal of high-level radioactive waste. The step-wise, incremental, learn-as-you-go approach is intended to

  11. Financial Literacy Education for Women

    Science.gov (United States)

    Jarecke, Jodi; Taylor, Edward W.; Hira, Tahira K.

    2014-01-01

    Exploring the pedagogical approaches of four women's financial literacy education programs, this chapter provides an overview of trends and needs in financial education for women and offers pedagogical strategies for teaching women about finance.

  12. Women and Diabetes -- Diabetes Medicines

    Science.gov (United States)

    ... Audience For Women Women's Health Topics Women and Diabetes - Diabetes Medicines Share Tweet Linkedin Pin it More sharing ... 1-800-332-1088 to request a form. Diabetes Medicines The different kinds of diabetes medicines are ...

  13. Women's Status on the Rise

    Institute of Scientific and Technical Information of China (English)

    LIU YUNYUN

    2010-01-01

    @@ On the afternoon of March 8,Beijing's department stores and shopping malls were crowded with women on shopping sprees to celebrate International Women's Day.This year marks the 100th anniversary of the establishment of International Women's Day.

  14. HIV in women

    Directory of Open Access Journals (Sweden)

    Mulcahy F

    2012-11-01

    Full Text Available Globally over 50% of HIV-infected individuals are women. With the widespread use of HAART, we can expect women to have mortality rates approaching normal. Indeed, studies have shown that women may expect a slower disease progression than men following seroconversion; furthermore, it appears that female who injects drugs can live longer than their male counterparts. However, other studies from cohort analysis have reported worse outcomes in women. In essence, many studies are consistently underpowered to adequately address these questions. The proportion of women in clinical trials remains at 20 to 30%, with pregnancy potential being a major exclusion factor. Hence, many questions remain unanswered. Recent data suggest women are more likely to present late with a new AIDS diagnosis. Why this should be the case is not well understood. In addition, HIV-positive women should have the same access to reproduction health as their negative counterparts, but unfortunately many inequalities remain. Advise on contraception and fertility services are very variable across both the developed and developing world. Data are limited on the most appropriate use of contraceptives in the presence of HAART, the possible drug interactions and possible increased risk of HIV transmission. There remain significant differences in guidelines regarding prevention of mother-to-child transmission (MTCT across Europe, and implications of stopping and starting HAART for MTCT have not been adequately addressed. The mode of timing of delivery, and the effect of length of time of ruptured membranes on this decision is also contentious. Further issues relate to the desire for HIV-positive women to breastfeed in the setting of HIV viral suppression, where some guidelines now support women in this situation and others categorically would inform child protection authorities. Finally as women age it is more difficult to separate the effect of the menopause and its symptoms from the

  15. Do women lack ambition?

    Science.gov (United States)

    Fels, Anna

    2004-04-01

    For men, ambition is considered a necessary and desirable part of life. Most women, however, associate ambition with egotism, self-aggrandizement, or manipulation. Getting to the bottom of why this is so required study of what ambition consists of--for both sexes. In childhood, the research uncovered, girls are clear about their ambitions. Their goals are grand, and they make no apologies for them. In nearly all childhood ambitions, two distinct factors are in place: the mastery of a special skill, and recognition for it. And what's true in childhood is no less true in later life: We all want our efforts and accomplishments acknowledged. Yet there are dramatic differences in how women and men create, reconfigure, and realize (or abandon) their goals. Most women are demure when praised for their achievements. One could chalk up this behavior to women's innate modesty or see it as a passive way of highlighting their accomplishments. But the fear of recognition that many women express suggests otherwise. Research has shown that such behavior varies according to social context: Women more openly seek and compete for affirmation when they are with other women, but they behave differently when competing with men. The underlying problem has to do with cultural ideals of femininity. Women face the reality that to appear feminine, they must provide or relinquish scarce resources to others--and recognition is indeed a scarce resource. Although women have more opportunities than ever before, they still come under social scrutiny that makes hard choices--such as when and whether to start a family or advance in the workplace--even harder. There are no easy solutions, but there are ways women can hold fast to their dreams. They must band together, learn to blow their own horns, and structure their lives in a way that promotes recognition.

  16. Stage-specific psychological determinants of stage transition

    NARCIS (Netherlands)

    Dijkstra, A.; Tromp, D; Conijn, B

    2003-01-01

    Objectives. The stages of change construct refers to the different psychological states people move through when they change their behaviour. However, the prediction that people in different stages of change need different sorts of interventions to stimulate the change process has scarcely been test

  17. Carboplatin and Paclitaxel With or Without Cisplatin and Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IVA Endometrial Cancer

    Science.gov (United States)

    2016-02-09

    Endometrial Clear Cell Adenocarcinoma; Endometrial Serous Adenocarcinoma; Stage IA Uterine Corpus Cancer; Stage IB Uterine Corpus Cancer; Stage II Uterine Corpus Cancer; Stage IIIA Uterine Corpus Cancer; Stage IIIB Uterine Corpus Cancer; Stage IIIC Uterine Corpus Cancer; Stage IVA Uterine Corpus Cancer

  18. SEXUAL ASSAULT ON WOMEN

    Directory of Open Access Journals (Sweden)

    Dara Durga

    2014-05-01

    Full Text Available Our India is a vast nation with rich cultural heritage and social diversity. We have been respecting women in the highest form as Goddesses since ages. There have been several laws to protect women from many centuries in this ancient country. Yet our country is still facing difficulties in achieving women safety. And the situation is no different in the rest of the world. The prevailing situation, laws and suggestions to prevent atrocities were discussed. AIM: The current situations of women hardships around the world were mentioned. The current legal situation and recent legal changes were described. The mammoth task ahead of us to achieve the desired social objective of women safety and respect were discussed. MATERIAL & METHODS: various news articles, police journals, legal textbooks and forensic medicine text books. CONCLUSION: Many things were done to prevent sexual assaults on women, yet the true goal is still a mirage. It’s time to look into the issue from its true grass root levels, i.e., from the psycho-social view apart from legal measures, to achieve the much desired objective of prevention of sexual assaults on women.

  19. WOMEN IN FAMILY BUSINESS

    Directory of Open Access Journals (Sweden)

    Mr Anshu

    2012-04-01

    Full Text Available The role of women in family businesses is explored in the paper. Although recognized as generally very important players, the role of women is often defined as invisible in business decision-making, supportive in men’s traditional business domains and only rarelyadequately recognized and rewarded. The paper explores possible differences in the views of men and women who manage small family firms. Their attitudes opposing the traditional business roles ofwomen, different views on managerial, ownership and transition issues and possible gender discrimination are examined. The findings support the paradigm of a different, more feminine style of management, while signs of discrimination are not clearly revealed. This paper is based on a research intended to provide acomparative analysis of the status of women entrepreneurs and men entrepreneurs in Family Business in India. It first draws demographic & psychographic profiles of women and men entrepreneurs in family business, identifies & addresses operational problems faced by women and men entrepreneurs in family business, draws theirinclination for future plans for growth and expansion and also for the furtherance of research on women entrepreneurs in India.

  20. Ten-Year Mortality after a Breast Cancer Diagnosis in Women with Severe Mental Illness

    DEFF Research Database (Denmark)

    Ribe, Anette Riisgaard; Laurberg, Tinne; Laursen, Thomas Munk

    2016-01-01

    % higher for women with SMI and breast cancer (MRR: 4.27, 95% CI: 3.98-4.57). Among women with both disorders, 15% of deaths could be attributed to interaction. In a sub-cohort of women with breast cancer, the ten-year all-cause-mortality was 59% higher after taking tumor stage into account (MRR: 1.59, 95...... to diagnostics, provision of care for breast cancer or physical comorbidity, health-seeking-behavior, and adherence to treatment....

  1. Sociodemographic and dietary profile of 4,471 childbearing-age women planning a pregnancy

    OpenAIRE

    Marta Cuervo; Leticia Goni; Susana Santiago; Itziar Zazpe; Aquilino García; J. Alfredo Martínez

    2014-01-01

    Background: The maintenance of healthy lifestyles is of great importance to prevent pregnancy-related diseases at early stages. For this reason, the knowledge of the overall wellbeing of women at childbearing-age is necessary to provide appropriate advice to maintain or improve the nutritional status. The aim of this research was to assess the lifestyles of childbearing-age women planning a pregnancy and to examine the difference between primiparae and multiparae women on these lifestyles. Me...

  2. High-Normal Estimated Glomerular Filtration Rate in Early-Onset Preeclamptic Women 10 Years Postpartum

    NARCIS (Netherlands)

    Paauw, Nina D.; Joles, Jaap A.; Drost, Jose T.; Verhaar, Marianne C.; Franx, Arie; Navis, Gerjan; Maas, Angela H. E. M.; Lely, A. Titia

    2016-01-01

    Women with a history of preeclampsia have a 5- to 12-fold increased risk to develop end-stage kidney disease. Previous observations in small cohorts suggest that former preeclamptic (fPE) women have subtle abnormalities in renal hemodynamics and renal function, which might predispose them to renal f

  3. The Impact of Education on Rural Women's Participation in Political and Economic Activities

    Science.gov (United States)

    Bishaw, Alemayehu

    2014-01-01

    This study endeavored to investigate the impact of education on rural women's participation in political and economic activities. Six hundred rural women and 12 gender Activists were selected for this study from three Zones of Amhara Region, Ethiopia using multi-stage random sampling technique and purposeful sampling techniques respectively.…

  4. Leadership Characteristics and Training Needs of Women and Men in Charge of Spanish Universities

    Science.gov (United States)

    Sánchez-Moreno, Marita; López-Yáñez, Julián; Altopiedi, Mariana

    2015-01-01

    This article discusses the results obtained by two consecutive enquiries into the leadership styles and training needs of women and men leading higher education organisations. It compares the findings of the first stage of two studies, based on ad hoc questionnaires responded to by 136 women and 129 men. Results showed only subtle differences…

  5. Early-Stage Breast Cancer in the Octogenarian: Tumor Characteristics, Treatment Choices, and Clinical Outcomes

    Science.gov (United States)

    Mamtani, Anita; Gonzalez, Julie J.; Neo, Dayna; Slanetz, Priscilla J.; Houlihan, Mary Jane; Herold, Christina I.; Recht, Abram; Hacker, Michele R.; Sharma, Ranjna

    2016-01-01

    Background Nodal staging with sentinel node biopsy (SLNB), post-lumpectomy radiotherapy (RT), and endocrine therapy (ET) for estrogen receptor-positive (ER+) tumors is valuable in the treatment of early-stage (stages 1 or 2) breast cancer but used less often for elderly women. Methods This retrospective study investigated women referred for surgical evaluation of biopsy-proven primary early-stage invasive breast cancer from January 2001 to December 2010. Clinicopathologic features, treatment course, and outcomes for women ages 80–89 years and 50–59 years were compared. Results The study identified 178 eligible women ages 80–89 years and 169 women ages 50–59 years. The elderly women more often had grade 1 or 2 disease (p = 0.003) and ER+ tumors (p = 0.007) and less frequently had undergone adjuvant therapies (all p ≤ 0.001). Lumpectomy was performed more commonly for the elderly (92 vs. 83 %, p = 0.02), and axillary surgery was less commonly performed (46 vs. 96 %; p < 0.001). Fewer elderly women had undergone post-lumpectomy RT (42 vs. 89 %; p < 0.001) and ET for ER+ tumors (72 vs. 95 %; p < 0.001). During the median follow-up period of 56 months for the 80- to 89-year old group and 98 months for the 50- to 59-year-old group, death from breast cancer was similar (4 vs. 5 %; p = 0.5). The two groups respectively experienced 7 versus 6 locoregional recurrences and 11 versus 13 distant recurrences. Conclusions The octogenarians had disease survivorship similar to that of the younger women despite less frequent use of adjuvant therapies, likely reflecting lower-risk disease features. Whether increased use of axillary surgery, post-lumpectomy RT, and/or ET for ER+ tumors would further improve outcomes is an important area for further study, but treatment should not be deferred solely on the basis of age. PMID:27364507

  6. Lernpunkt Deutsch--Stage 1.

    Science.gov (United States)

    Theil, Elvira

    1997-01-01

    Evaluates the first stage of "Lernpunkt Deutsch," a new three-stage German course designed for upper elementary and early secondary school. Describes the publisher's package of materials and the appropriateness of the course, utility of the different package elements, format of the materials, and assesses whether the course provides pedagogically…

  7. Writing Stages: A Developmental Hierarchy.

    Science.gov (United States)

    Milner, Joseph O.

    The developmental stages of writing can be related to Jean Piaget's final three stages of development (preoperational, concrete operational, and formal operational) and to the narrative, descriptive, explanative, analytical, and artistic rhetorical modes. As the child enters kindergarten or the first grade, narrative blooms. By this age most young…

  8. Smoking and women's health.

    Science.gov (United States)

    Seltzer, V

    2000-07-01

    Each year more than 600000 women have deaths associated with cigarette smoking. In addition, cigarette smoking is associated with a wide array of morbidities (such as osteoporosis, cardiovascular disease, and adverse pregnancy outcomes). Two hundred million women smoke worldwide, and this number appears to be rising, particularly in developing countries. Obstetrician-gynecologists can play a role in reducing morbidity and mortality from cigarette smoking by educating women about the dangers, advising them not to smoke, and assisting those who do smoke to quit.

  9. Hereditary angioedema in women

    Directory of Open Access Journals (Sweden)

    Bouillet Laurence

    2010-07-01

    Full Text Available Abstract Women with hereditary angioedema (HAE are more likely to be symptomatic that men. Hormonal factors (puberty, contraception, pregnancy,.... play a significant role in the precipitation or worsening of the condition in women. So, combined contraceptive pills are not indicated and progestogen pill must be preferred. During pregnancy, attack rate can increase (38-48% of women. C1Inhibitor concentrate and tranexamic acid can be used during pregnancy. Attenuated androgens for long term prophylaxis are effective but side effects appear more often in female patients. These side effects are dose dependant and can be attenuated by titrating the dose down the lowest effective level.

  10. Migraine in women.

    Science.gov (United States)

    Lay, Christine L; Broner, Susan W

    2009-05-01

    Of the nearly 32 million Americans with migraine, 24 million are women. It is a disorder affecting women throughout their lifetimes, from childhood and puberty through the postmenopausal years. In childhood, before puberty girls are afflicted with migraine at approximately the same rate as boys, but after puberty, there is an emerging female predominance. Estrogen plays a key role in this epidemiologic variation but is not the only factor. There are numerous times when hormonal influences have an impact on migraine and its pattern, including menarche, oral contraceptive use, pregnancy, perimenopause, and menopause. Hence practitioners treating women with migraine need to have a clear understanding of these special considerations.

  11. Women in extreme poverty.

    Science.gov (United States)

    1994-01-01

    Population is estimated to increase from 5.5 billion in 1990 to 10 billion by 2050; the poverty level is expected to increase from 1 billion to 2-3 billion people. Women in development has been promoted throughout the UN and development system, but women in poverty who perform work in the informal sector are still uncounted, and solutions are elusive. The issue of extreme poverty can not be approached as just another natural disaster with immediate emergency relief. Many people live in precarious economic circumstances throughout their lives. Recent research reveals a greater understanding of the underlying causes and the need for inclusion of poor women in sustainable development. Sanitation, water, housing, health facilities need to be improved. Women must have access to education, opportunities for trading, and loans on reasonable terms. UNESCO makes available a book on survival strategies for poor women in the informal sector. The profile shows common problems of illiteracy, broken marriages, and full time involvement in provision of subsistence level existence. Existence is a fragile balance. Jeanne Vickers' "Women and the World" offers simple, low cost interventions for aiding extremely poor women. The 1992 Commission on the Status of Women was held in Vienna. Excerpts from several speeches are provided. The emphasis is on some global responses and an analysis of solutions. The recommendation is for attention to the gender dimension of poverty. Women's dual role contributes to greater disadvantages. Women are affected differently by macroeconomic factors, and that there is intergenerational transfer of poverty. Social services should be viewed as investments and directed to easing the burdens on time and energy. Public programs must be equipped to deal with poverty and to bring about social and economic change. Programs must be aware of the different distribution of resources within households. Women must be recognized as principal economic providers within

  12. Ten Outstanding Women Chosen

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    BEFORE the celebration of the 85th anniversary of International Women’s Day, the All-China Women’s Federation sponsored an activity to choose ten outstanding Chinese women, which involved the Ministries of Labor and Personnel, the General Political Department of the People’s Liberation Army, the All-China Federation of Trade Union, the Youth League of China, the China Association of Science and about a dozen Chinese news agencies. The results were recently announced, and including following women: Yue Xicui, one of the third generation of women aviators. Since she joined the air force she has accumulated 5,180 hours

  13. Plasma androgenic activity in women with acne vulgaris and in healthy girls before, during and after puberty.

    Science.gov (United States)

    Odlind, V; Carlström, K; Michaëlsson, G; Vahlqvist, A; Victor, A; Mellbin, T

    1982-03-01

    The possible relationship between plasma androgenic activity and acne vulgaris was investigated. Plasma testosterone and sex hormone binding globulin (SHBG) levels were determined in healthy girls during different stages of puberty, in healthy adult women and in women with acne vulgaris. Testosterone increase during puberty, whereas SHBG decreased during the early stages before it increased and stabilized plasma concentrations of testosterone and SHBG. Women with severe acne vulgaris had testosterone levels in the same range but the SHBG levels were significantly lower than those of healthy women and women with mild acne. These results show a high androgenic activity in the intermediate stages of puberty, when acne vulgaris is a common complaint and an increased androgenic activity in adult women with severe acne vulgaris.

  14. Multi-stage complex contagions

    Science.gov (United States)

    Melnik, Sergey; Ward, Jonathan A.; Gleeson, James P.; Porter, Mason A.

    2013-03-01

    The spread of ideas across a social network can be studied using complex contagion models, in which agents are activated by contact with multiple activated neighbors. The investigation of complex contagions can provide crucial insights into social influence and behavior-adoption cascades on networks. In this paper, we introduce a model of a multi-stage complex contagion on networks. Agents at different stages—which could, for example, represent differing levels of support for a social movement or differing levels of commitment to a certain product or idea—exert different amounts of influence on their neighbors. We demonstrate that the presence of even one additional stage introduces novel dynamical behavior, including interplay between multiple cascades, which cannot occur in single-stage contagion models. We find that cascades—and hence collective action—can be driven not only by high-stage influencers but also by low-stage influencers.

  15. The Right for Women--After Professions for women

    Institute of Scientific and Technical Information of China (English)

    郑文莉

    2000-01-01

    Woolfwas a flag of right fighter for women. Women fight for their rights genaration after genaration and devote themselves in different professions like men. It was proved that women can do every thing as they are willing ,women can creat many outstanding achievements in their professional life.

  16. TNM staging and classification (familial and nonfamilial of breast cancer in Jordanian females

    Directory of Open Access Journals (Sweden)

    M F Atoum

    2010-01-01

    Full Text Available Purpose : Staging of breast tumor has important implications for treatment and prognosis. This study aims at pinpointing the frequency of each stage among familial and nonfamilial breast cancers. Materials and Methods : Ninety-nine Jordanian females diagnosed with familial and nonfamilial breast cancer between 2000 and 2002 were enrolled in this study All breast cancer cases were staged according to the TNM classification into in situ, early invasive, advanced invasive and metastatic. Results : Forty-three cases were familial breast cancer and 56 were nonfamilial. One female breast cancer was diagnosed with ductal carcinoma in situ (DCIS cancer. Fifty cases were diagnosed in early stages of invasive breast cancer, of which 31 cases were familial, 29 cases were classified as advanced invasive, where 21 cases were nonfamilial and 19 cases were metastatic stage of breast cancer, with 16 nonfamilial cases. Stage 2b was the most common stage of early invasive cases and represented 48% of the early stage of breast cancer. On the other hand, among cases diagnosed with advanced invasive breast cancer, stage 3a was the most common stage and represented 89.6% of the advanced stage. Interestingly, all cases of stage 3a belonged to TNM stages of T2N2M0 and T3N1M0. The tumor size in all cases of Jordanian females diagnosed with advanced invasive breast cancer exceeded 2 cm in size due to selection bias from symptomatic women in our study. Conclusion : The incidence of nonfamilial breast cancer was slightly higher than that of the familial type amongst studied the Jordanian females studied. The early invasive stage of breast cancer was more common in the familial while the advanced invasive and metastatic breast cancer cases were encountered more often in the nonfamilial type. Our study was based on a small sample and symptomatic women. Therefore, more research with larger population samples is needed to confirm this conclusion.

  17. Women's decision to major in STEM fields

    Science.gov (United States)

    Conklin, Stephanie

    This paper explores the lived experiences of high school female students who choose to enter into STEM fields, and describes the influencing factors which steered these women towards majors in computer science, engineering and biology. Utilizing phenomenological methodology, this study seeks to understand the essence of women's decisions to enter into STEM fields and further describe how the decision-making process varies for women in high female enrollment fields, like biology, as compared with low enrollment fields like, computer science and engineering. Using Bloom's 3-Stage Theory, this study analyzes how relationships, experiences and barriers influenced women towards, and possibly away, from STEM fields. An analysis of women's experiences highlight that support of family, sustained experience in a STEM program during high school as well as the presence of an influential teacher were all salient factors in steering women towards STEM fields. Participants explained that influential teacher worked individually with them, modified and extended assignments and also steered participants towards coursework and experiences. This study also identifies factors, like guidance counselors as well as personal challenges, which inhibited participant's path to STEM fields. Further, through analyzing all six participants' experiences, it is clear that a linear model, like Bloom's 3-Stage Model, with limited ability to include potential barriers inhibited the ability to capture the essence of each participant's decision-making process. Therefore, a revised model with no linear progression which allows for emerging factors, like personal challenges, has been proposed; this model focuses on how interest in STEM fields begins to develop and is honed and then mastered. This study also sought to identify key differences in the paths of female students pursuing different majors. The findings of this study suggest that the path to computer science and engineering is limited. Computer

  18. Relationship between serum trace elements and antioxidant capacity indexes in women of hypertensive disorder complicating pregnancy

    Institute of Scientific and Technical Information of China (English)

    Yang Liu; Mei Xu; Ying Jiang; Yan Zhang

    2016-01-01

    Objective:To analyze the relationship between serum trace elements, antioxidant capacity index and hypertensive disorder complicating pregnancy (HDCP). Methods: Forty cases of normal healthy pregnant women, twenty-one pregnant women with high blood pressure, twenty-eight pregnant women with early stage of mild preeclampsia and twenty-two pregnant women with early stage of severe preeclampsia were selected respectively. Then, the differences of blood routine examination and blood coagulation function of the four groups were compared. At the same time, the levels of the serum trace elements and oxidative stress related indexes in the placental villi tissue were determined by flame atomic absorption spectrometry. Results:The white blood cells and hematocrit of HDCP pregnant women were significantly higher than those of normal healthy pregnant women;platelet and fibrinogen levels were obviously lower than those of normal healthy pregnant women, while thrombin time was shorter than that of normal healthy pregnant women;levels of serum copper, zinc and manganese were also significantly lower than whose of normal healthy pregnant women, while iron level was distinctly higher than that of normal healthy pregnant women. The differences between groups were statistically significant. The activities of SOD and GSH-PX in the placental villi tissue of HDCP pregnant women were significantly smaller than those of normal healthy pregnant women, while the Hcy level was higher than that of normal healthy pregnant women. The differences between groups were statistically significant. Conclusions:Pregnant women with HDCP has both imbalance of trace elements and redox system equilibrium, so we should strengthen the determination of the trace elements and redox related indexes of HDCP pregnant women to ensure health of maternal and child.

  19. 不同生理阶段更年期综合征证候规律及治疗的临床研究%Clinical study on distribution rule of TCM syndromes and treatment of climacteric syndrome among patients in different menopausal status

    Institute of Scientific and Technical Information of China (English)

    靳岭; 王兴娟

    2011-01-01

    目的:探讨不同生理阶段女性更年期综合征(CS)患者中医证型分布规律及CS与性激素、糖脂代谢之间的关系,为本病的临床治疗提供依据.方法:随机选择绝经前期、围绝经期、绝经后期更年期综合征患者各50例,辨证后给予相应中药服用6周,治疗前后分别进行问卷调查及血清检测.结果:不同生理阶段女性CS患者中医证型的构成比存在差异;中药治疗后患者的更年期症状均明显改善,Kupperman评分降低(P<0.01),雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)、睾酮(T)水平无明显变化;脾虚组患者的空腹血糖(FBG)、空腹胰岛素(FINS)、胰岛素抵抗指数(HOMA-IR)、瘦素(leptin)较治疗前均降低;肝虚组患者的高密度脂蛋白(HDL)较前升高;肾虚组患者的FBG、总胆固醇(TC)较前降低(P<0.05,P<0.01).结论:不同生理阶段的女性CS患者中医证型分布存在一定规律;本病的发病可能与心血管疾病风险因素有关,其治疗应该重视糖脂代谢功能的调节.%Objective: To explore the distribution rule of TCM (TCM) syndromes of patients with climacteric syndrome (CS) in different menopausal status and the association between CS and sex hormone as well as glucolipid metabolism, and to supply credible evidence for the clinical therapy of CS.Methods: Randomly selected patients with CS 50 cases in premenopausal,perimenopausal, postmenopansal status separately.After differentiation, the patients were treated with the appropriate Chinese medicine for 6 weeks.Questionnaire survey and serum testing were conducted before and after treatment.Results: The constituent ratio of TCM syndromes was different among CS patients in different menopausal status.The climacteric syndrome was significantly improved in patients of all 3 groups after treatment, kupperman score was markedly reduced(P<0.01), but the level of endocrine hormone (F2, FSH, LH, T) didn't show any change.In the spleen deficiency

  20. A Stress and Coping Approach to Intervention with Abused Women.

    Science.gov (United States)

    Carlson, Bonnie E.

    1997-01-01

    Presents an ecological model of intervention for physical abuse based on the Lazarus and Folkman conceptualization of stress and coping. Claims that the model identifies the stages that abused women may experience in their appraisal of the abuse experience. Focuses on barriers to ending abuse, stress and coping, and effective interventions. (RJM)

  1. Pregnancy in end-stage renal disease patients on dialysis: how to achieve a successful delivery.

    Science.gov (United States)

    Manisco, Gianfranco; Potì', Marcello; Maggiulli, Giuseppe; Di Tullio, Massimo; Losappio, Vincenzo; Vernaglione, Luigi

    2015-06-01

    Pregnancy in women with chronic kidney disease has always been considered as a challenging event both for the mother and the fetus. Over the years, several improvements have been achieved in the outcome of pregnant chronic renal patients with increasing rates of successful deliveries. To date, evidence suggests that the stage of renal failure is the main predictive factor of worsening residual kidney function and complications in pregnant women. Moreover, the possibility of success of the pregnancy depends on adequate depurative and pharmacological strategies in patients with end-stage renal disease. In this paper, we propose a review of the current literature about this topic presenting our experience as well.

  2. Health screening - women - ages 40 to 64

    Science.gov (United States)

    Health maintenance visit - women - ages 40 to 64; Physical exam - women - ages 40 to 64; Yearly exam - ... 64; Checkup - women - ages 40 to 64; Women's health - ages 40 to 64; Preventive care - women - ages ...

  3. Health screening - women - ages 18 to 39

    Science.gov (United States)

    Health maintenance visit - women - ages 18 to 39; Physical exam - women - ages 18 to 39; Yearly exam - ... 39; Checkup - women - ages 18 to 39; Women's health - ages 18 to 39; Preventive care - women - ages ...

  4. Violence against Women

    Science.gov (United States)

    ... These forms of violence can lead to depression, post-traumatic stress and other anxiety disorders, sleep difficulties, eating disorders, and suicide attempts. The same study found that women who ...

  5. Heart disease and women

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007188.htm Heart disease and women To use the sharing features on ... please enable JavaScript. People often DO NOT consider heart disease a woman's disease. Yet cardiovascular disease is the ...

  6. Women and Cholesterol

    Science.gov (United States)

    ... Disease Venous Thromboembolism Aortic Aneurysm More Women and Cholesterol Updated:Apr 1,2016 The female sex hormone ... 2014. Related Sites Nutrition Center My Life Check Cholesterol • Home • About Cholesterol • Why Cholesterol Matters • Understand Your ...

  7. Women and Mice

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is an advertisement for Dr. Pierce's "Favorite Prescription," which he developed in the 1880's to relieve women of nervous symptoms caused by disease of the...

  8. Conservation among Elderly Women.

    Science.gov (United States)

    Hughston, George A.; Protinsky, Howard O.

    1979-01-01

    The majority of 63 elderly women were able to pass tests in the conservation of mass (98 percent), volume (100 percent), and surface area (65 percent). These results conflict with previous research about Piagetian abilities of elderly people. (RL)

  9. Sexual Dysfunction in Women

    Science.gov (United States)

    ... your sex life. Certain medicines (such as oral contraceptives and chemotherapy drugs), diseases (such as diabetes or ... have heard that taking sildenafil (Viagra) or the male hormone testosterone can help women with sexual problems. ...

  10. Women's Health Insurance Coverage

    Science.gov (United States)

    ... adopted policies that specifically placed women at a disadvantage, either by charging them higher premiums than men ... SOURCE: Kaiser Family Foundation analysis of 2016 ASEC Supplement to the Current Population Survey, U.S. Census Bureau. ...

  11. Women and Diabetes

    Medline Plus

    Full Text Available ... awareness about diverse women of different ages, races, ethnic backgrounds, and health conditions participating in clinical trials. ... FEAR Act Site Map Nondiscrimination Website Policies U.S. Food and Drug Administration 10903 New Hampshire Avenue Silver ...

  12. Women, Men, and Machines.

    Science.gov (United States)

    Form, William; McMillen, David Byron

    1983-01-01

    Data from the first national study of technological change show that proportionately more women than men operate machines, are more exposed to machines that have alienating effects, and suffer more from the negative effects of technological change. (Author/SSH)

  13. Democracy and Women's Health

    Directory of Open Access Journals (Sweden)

    Jalil Safaei

    2009-07-01

    Full Text Available New research on broader determinants of health has culminated into the new paradigm of social determinants of health. The fundamental view that underlies this new paradigm is that socioeconomic and political contexts in which people live have significant bearing upon their health and well-being. Unlike a wealth of research on socioeconomic determinants, few studies have focused on the role of political factors. Some of these studies examine the role of political determinants on health through their mediation with the labour environments and systems of welfare state. A few others study the relationship between polity regimes and population health more directly.However, none of them have a focus on women's health.This study explores the interactions, both direct and indirect, between democracy and women's health. In doing so, it identifies some of the main health vulnerabilities for women and explains, through a conceptual model, how democracy and respect for human rights interacts with women's health.

  14. Sexual Health (Women)

    Science.gov (United States)

    ... gift today will help us get closer to curing diabetes and better treatments for those living with ... you can still get pregnant. Most birth control methods are safe for women with diabetes. Talk with ...

  15. Mostly Women and Leadership.

    Science.gov (United States)

    Barron, Daniel D.

    1996-01-01

    Discusses educational leadership and women with a focus on roles, characteristics, stereotypes, and change. Describes some sources that deal with this topic, including an article, a study, two books, and some websites. (AEF)

  16. Women and Diabetes

    Medline Plus

    Full Text Available ... How to Report Problems with Glucose Meters Diabetes Treatments Some people with diabetes need to take diabetes ... with your health care provider about your diabetes treatment. Diabetes Medicines - easy-to-read booklet for women ...

  17. Drum Performance Tnvolues Women

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    DRUM teams from along the Yellow River are known not only in China but by many foreign friends. Recently women have formed their own teams and their performances have further increased the popularity of this ancient Chinese folk art.

  18. Women Astronomers through History

    Science.gov (United States)

    Dobrosavljevic-Grujic, Lj.

    2008-10-01

    We review the contributions of women to astronomy starting from the antique Greece and Alexandria, and mention briefly some works of nun-scientists in the Middle Ages, which are of interest only for keeping alive the spirit of inquiry during this Dark Age. We discuss in more details important contributions coming after the Scientific Revolution and Enlightenment, made by women working within their families, as assistants to their brothers or husbands. We show that by the late 19th century the role of women in astronomy becomes more independent, with more women working not only as "computers" in the great observatories, but also making important discoveries that placed them in a very high position as scientists at the dawn of 20th century.

  19. Women in Transition

    OpenAIRE

    UNICEF Innocenti Research Centre. MONEE project

    1999-01-01

    The 1999 Central and Eastern Europe and Commonwealth of Independent States Regional Monitoring Report focuses on the experiences of girls and women during the transition, highlighting their role in regional progress and the obstacles they face. The Report covers a broad range of issues, including women’s participation in the emerging market economy and democratic governments, female access to health and education, trends in family formation and violence against women and girls. The Report cal...

  20. Maintaining women's oral health.

    Science.gov (United States)

    McCann, A L; Bonci, L

    2001-07-01

    Women must adopt health-promoting strategies for both general health and the oral cavity, because the health of a woman's body and oral cavity are bidirectional. For general health-maintenance strategies, dental practitioners should actively advise women to minimize alcohol use, abstain from or cease smoking, stay physically active, and choose the right foods to nourish both the body and mind. For oral health-maintenance strategies, dental practitioners should advise women on how to prevent or control oral infections, particularly dental caries and periodontal diseases. Specifically, women need to know how to remove plaque from the teeth mechanically, use appropriate chemotherapeutic agents and dentifrices, use oral irrigation, and control halitosis. Dental practitioners also need to stress the importance of regular maintenance visits for disease prevention. Adolescent women are more prone to gingivitis and aphthous ulcers when they begin their menstrual cycles and need advice about cessation of tobacco use, mouth protection during athletic activities, cleaning orthodontic appliances, developing good dietary habits, and avoiding eating disorders. Women in early to middle adulthood may be pregnant or using oral contraceptives with concomitant changes in oral tissues. Dental practitioners need to advise them how to take care of the oral cavity during these changes and how to promote the health of their infants, including good nutrition. Older women experience the onset of menopause and increased vulnerability to osteoporosis. They may also experience xerostomia and burning mouth syndrome. Dental practitioners need to help women alleviate these symptoms and encourage them to continue good infection control and diet practices.

  1. Avaliação da capacidade orgástica em mulheres na pós-menopausa Assessment of orgasmic capacity of postmenopausal women

    Directory of Open Access Journals (Sweden)

    Sonia Regina Lenharo Penteado

    2004-12-01

    Full Text Available OBJETIVO: Correlacionar a capacidade orgástica (durante a relação sexual e/ou a masturbação solitária de mulheres pós-menopausadas, saudáveis e sem tratamento hormonal com fatores climatéricos, psicossociais, comportamentais, hormonais e interpessoais. MÉTODOS: De um total de 999 mulheres avaliadas com idade entre 41 e 60 anos, selecionaram-se 60 mulheres saudáveis, sexualmente ativas, com pelo menos um ano de amenorréia, útero íntegro, relacionamento estável com parceiro capacitado ao coito e não usuárias de terapia hormonal. Elaborou-se um modelo estatístico de regressão logística que avaliou a capacidade de orgasmo (variável dependente em função de 17 variáveis independentes, que representavam fatores psicossociais, comportamentais, interpessoais, climatéricos e hormonais. RESULTADOS: A capacidade orgástica está significativamente correlacionada à prática da masturbação (p=0,000, ao gostar de abraçar e acariciar o corpo do parceiro (p= 0,036 e à presença de secura vaginal (p=0,021. CONCLUSÕES: Nas mulheres pós-menopausadas avaliadas, a capacidade orgástica relacionou-se positivamente com o relacionamento mais afetivo com o companheiro e com a prática da masturbação. Mulheres que apresentam secura vaginal, mas que praticam a masturbação e mantêm relacionamento afetivo com o parceiro, conseguem obter o mesmo número ou um número maior de orgasmos se comparados à freqüência do coito.OBJECTIVE: To correlate the capacity of healthy postmenopausal women to have orgasms (during intercourse or by solitary masturbation with psychosocial, behavioral, climacteric, hormonal and interpersonal factors. METHODS: Nine hundred and ninety-nine women (aged from 41 to 60 years underwent physical and supplementary tests and answered questionnaires regarding sexual behaviour. Sixty healthy women, sexually active, with one or more years of amenorrhea, without hormone therapy and with a partner capable of intercourse

  2. Staging of unipolar affective illness

    Directory of Open Access Journals (Sweden)

    Ewa Ferensztajn

    2014-12-01

    Full Text Available In this article, a concept of staging of unipolar affective illness (recurrent depression is presented. In respective subchapters, three most important aspects of this issue have been discussed: 1 staging of unipolar affective illness; 2 staging of treatment-resistant depression; and 3 conversion of unipolar into bipolar affective illness. The evidence for so called neuroprogression of the illness, accumulated in recent years, has allowed for a classification of staging based on a concept of allostasis and allostatic load. In the course of illness, changes in neuroendocrine system (mainly hypothalamic pituitary-adrenal (HPA axis, immunological system, mechanisms of oxidative stress, neurotransmitters, neurotrophic factors as well as structural and functional changes of the brain occur. In their paper of 2007, Fava and Tossani elaborated a concept of staging of unipolar affective illness presenting a continuum model of five consecutive stages with specific clinical features. In the present paper, a concept of treatment-resistant depression and staging of treatment resistance is presented in the context of several models. An important determinant of treatment-resistant depression is so called subthreshold bipolarity which is connected with worse efficacy of antidepressant drugs. In the course of illness, there is a possibility of changing diagnosis from recurrent depression into bipolar affective illness. The studies on this issue show that frequency of such diagnostic conversion is 1,5% of depressed patients per year.

  3. Management of the axilla in women with breast cancer.

    Science.gov (United States)

    Benson, J R; Querci della Rovere, G

    2007-04-01

    There remain several outstanding questions relating to management of the axilla in women with early stage breast cancer. This paper summarises the outcome of a national debate aimed at discussing certain key issues including a) whether axillary dissection has any survival advantage b) is an axillary staging procedure always necessary c) what is the optimum method of staging the axilla and d) whether an axillary dissection is always necessary in cases of a positive sentinel node. Electronic voting was undertaken at the beginning and end of the debate and results are compared and presented herein.

  4. An Extraordinary Century for Women

    Science.gov (United States)

    Gerlach, Jeanne Marcum

    2011-01-01

    "Missing Chapters: Ten Pioneering Women in NCTE and English Education" is the first historical text to explore the impact women have had on English education. It is true that women have been a vital part of National Council of Teachers of English (NCTE) since the Council's founding in 1911 when 13 of the 34 founding members were women. As part of…

  5. Women in Italian astronomy

    CERN Document Server

    Matteucci, Francesca

    2014-01-01

    This document gives some quantitative facts about the role of women in Italian astronomy. More than 26% of Italian IAU members are women: this is the largest fraction among the world leading countries in astronomy. Most of this high fraction is due to their presence in INAF, where women make up 32% of the research staff (289 out of 908) and 40% of the technical/administrative staff (173 out of 433); the percentage is slightly lower among permanent research staff (180 out of 599, about 30%). The presence of women is lower in the Universities (27 out of 161, about 17%, among staff). In spite of these (mildly) positive facts, we notice that similarly to other countries (e.g. USA and Germany) career prospects for Italian astronomers are clearly worse for women than for men. Within INAF, the fraction of women is about 35-40% among non-permanent position, 36% for Investigators, 17% for Associato/Primo Ricercatore, and only 13% among Ordinario/Dirigente di Ricerca. The situation is even worse at University (only 6% ...

  6. Women and AIDS: introduction.

    Science.gov (United States)

    Krieger, N; Margo, G

    1991-01-01

    Around the world, more and more women--principally poor women of color--are being diagnosed with and are dying of AIDS, the acquired immune deficiency syndrome. Yet, effective and appropriate prevention programs for women are sorely missing from the global program to control AIDS. To help us understand why this gap exists, and what we must do to close it, the three articles in this issue focus on women and AIDS. Examining the situation in such countries as Zimbabwe and South Africa, as well as in other economically underdeveloped and developed regions, the authors argue that women with the least control over their bodies and their lives are at greatest risk of acquiring AIDS. For example, the high rate of infection among women in Africa cannot be understood apart from the legacy of colonialism (including land expropriation and the forced introduction of a migrant labor system) and the insidious combination of traditional and European patriarchal values. Only by recognizing the socioeconomic and cultural determinants of both disease and sexual behavior, and only by incorporating these insights into our AIDS prevention programs, will we be able to curb the spread of this lethal disease.

  7. Violence against women.

    Science.gov (United States)

    1995-04-01

    Domestic violence constitutes historical behavior in accord with patriarchal systems. Family and domestic violence includes female infanticide, higher female mortality, female genital mutilation, bride burning, rape, wife battering, and early marriage. These practices are commonly integrated into values and beliefs. Women accept domestic violence in violation of their basic human rights due to social prejudice and low self esteem. Mothers who perpetuate female genital mutilation believe that they are acting in the best interests of the child by adhering to centuries-long traditions. Women who allow female infanticide or female abortion are motivated to do so in order to maintain the security of their marriage. Women are in unequal power relationships and submit to their own detriment. Negative attitudes against women are perpetuated through incorrect interpretations of religious principles and myths. Economic self-reliance gives women the courage to stand up against domestic violence. Empowerment through education and appropriate and protective legislation also gives women the means to fight violence. Nongovernmental organizations (NGOs) at the national, regional, and international levels are active in creating awareness of domestic violence and influencing policy change. The NGO Working Group on Traditional Practices and the Inter-African Committee have a 10-year history of fighting against practices such as female genital mutilation. In order to bring about change, there must be cooperative and joint action among governmental and inter-governmental groups and NGOs.

  8. Comparison of lifestyle in women with polycystic ovary syndrome and healthy women.

    Science.gov (United States)

    Sedighi, Sedigheh; Amir Ali Akbari, Sedigheh; Afrakhteh, Maryam; Esteki, Taraneh; Alavi Majd, Hamid; Mahmoodi, Zohreh

    2014-08-31

    Given the high prevalence of polycystic ovary syndrome (PCOS), and that a lifestyle is recognized effective in development of many diseases, this study aimed to compare lifestyle of women with PCOS and healthy women. Nor are there sufficient studies on the difference between lifestyle of these people with that of healthy people. Furthermore, studies show that changes in lifestyle improve this disease. This descriptive-comparative study was conducted on 65 women with PCOS and 65 healthy women of 18 to 45 years old who presented to hospitals affiliated to Shahid Beheshti University of Medical Sciences in 2013. The subjects were selected using multi stage random sampling method. The data were collected using questionnaires for diet, International Physical Activity Questionnaire, and unhealthy behaviors and were analyzed in SPSS v. 17, using descriptive statistics, Man-Whitney, independent t, Chi-square and logistic regression tests. The results showed there was a significant relationship between PCOS and inappropriate diet (p=0.009), low physical activity (p=0.009), but no relationship was observed between PCOS and unhealthy behaviors. Given the results obtained, training and awareness raising is necessary for women and girls especially about appropriate diet and regular physical activity.

  9. Staging procedures in mycosis fungoides

    Energy Technology Data Exchange (ETDEWEB)

    Griem, M.L.; Moran, E.M.; Ferguson, D.J.; Mettler, F.A.; Griem, S.F.

    1975-01-01

    Mycosis fungoides (MF) in deep-seated lymph nodes, spleen or liver appears to be associated with a lack of response of the disease to topical external therapy. Fourteen patients with mycosis fungoides were clinically staged and had a staging laparotomy. Myosis fungoides was found in the lymph nodes of 3 of these patients, in the spleen in 4 and in the liver of 2 cases. Patients with adenopathy, or with splenomegaly or abnormal spleen scans, should be considered for surgical staging to determine the extent of extracutaneous disease. The documentation of extracutaneous MF becomes necessary in the development of new therapeutic approaches. (auth)

  10. Women Status and their Discrimination

    OpenAIRE

    PEŠKOVÁ, Pavlína

    2008-01-01

    My work deal with women status and their discrimination. Chapter one contains women status in different historical periods and development of their status to bigger equal with men. There is also written about present feminist trends. Chapter two is about women discrimination. There is about women´ job discrimination, job segregation according to gender and inequality in payment. There is also written about women status at home and unequal duties at home among family mates. Chapter three is ab...

  11. CalCOFI Larvae Stages

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Developmental stages (yolk sac, preflexion, flexion, postflexion, or transformation) of selected fish larvae captured in CalCOFI icthyoplankton nets.

  12. State-Run Enterprises Find New Posts for Women Workers

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    WHEN the market economy took the place of the planned economy, Chinese society entered a stage of transformation. This transformation brought about the reform of the labor management system. And with it, the contradiction hidden within the old mode of "full employment for women" was exposed. Market competition is doomed to be a competition of talent. A considerable number of women factory workers who can’t adapt to a competitive workforce have been sifted out. These women who had immersed themselves in their jobs for many years and had gotten used to connecting their individual lives with the destiny of the enterprise couldn’t accept this reality. Chinese women have made tremendous efforts to leave their homes in favor of working in factories;

  13. Pregnancy in PCOS women and their history of diabetes

    DEFF Research Database (Denmark)

    Viftrup-Lund, Mette; Gade, Melina; Lauszus, Finn

    2014-01-01

    Objective: Evaluation of the incidence of gestational diabetes in PCOS women treated with metformin before and during early pregnancy and to ascertain their family history of diabetes. Design: Follow-up on all women with PCOS and infertility who received treatment with metformin prior to pregnancy...... (=index pregnancy) during 10 years. Data on diabetes was retrieved by questionnaire and hospital charts. Main outcome measures: Incidence of gestational diabetes, pregnancy outcome, and fetal size Results: In 18 % of the women GDM was diagnosed at some stage. The clinical and obstetrical outcome...... of the women showed no association with family history of diabetes or GDM. No neonatal anthropometric feature was different with respect to family history of diabetes or GDM and no fetal malformations were found Conclusion: GDM and family history of diabetes seem not to be associated with unfavourable...

  14. The Contemporary Women's Movement and Women's Education in India

    Science.gov (United States)

    Patel, Ila

    1998-03-01

    The contemporary women's movement in India (1975-present) has played an important role in bringing gender issues to the forefront of development planning and defining feminist politics. This paper examines how this movement has addressed the issue of women's education. The first section highlights contributions of the social reformist movement in the 19th century and the nationalist movement in promoting women's education. The role of the contemporary women's movement in changing school curricula is examined in the second section, followed by discussion on how women's studies has contributed to redefining knowledge. The fourth section discusses women's empowerment and education from the perspective of the women's movement. The article concludes by highlighting challenges facing the women's movement in promoting women's education for equality and empowerment.

  15. Androgens and women's health.

    Science.gov (United States)

    Redmond, G P

    1998-01-01

    Androgenic disorders are those conditions in women characterized by excessive androgen action. They are the most common endocrinopathy of women, affecting from 10% to 20%. Signs are: persistent acne, hirsutism and androgenic alopecia, which is the female equivalent of male pattern baldness. A subgroup, those traditionally labeled as having polycystic ovary syndrome (PCOS), additionally have anovulation, as well as menstrual abnormalities and, often, obesity. Although women with androgenic disorders usually present themselves for help with the skin or menstrual changes, there are other important implications regarding their health. Women with PCOS have varying degrees of insulin resistance, and an increased incidence of Type II diabetes mellitus, as well as unfavorable lipid patterns. The presence of these risk factors is suggested by upper segment obesity, darkening of the skin, and the other skin changes that make up acanthosis nigricans. Diagnosis involves measurement of circulating androgens (of which free testosterone is most important), together with prolactin and FSH when menstrual dysfunction is present. Many women with androgenic skin changes have normal serum androgen levels, suggesting increased end organ sensitivity to androgens. Others have hyperandrogenism (of ovarian or adrenal origin). Treatment is usually successful in controlling acne, reducing hirsutism and stabilizing, or partially reversing, androgenic alopecia. Pharmacological approaches involve suppressing androgen levels, for example, the use of an appropriate oral contraceptive, or antagonizing androgen action with several medications that have this activity. Unfortunately, most women with androgenic disorders are frustrated in their efforts to obtain medical help. Understanding androgenic disorders will enable the physician to significantly help the majority of women with these conditions.

  16. Staged regenerative sorption heat pump

    Science.gov (United States)

    Jones, Jack A. (Inventor)

    1995-01-01

    A regenerative adsorbent heat pump process and system for cooling and heating a space. A sorbent is confined in a plurality of compressors of which at least four are first stage and at least four are second stage. The first stage operates over a first pressure region and the second stage over a second pressure region which is higher than the first. Sorbate from the first stage enters the second stage. The sorbate loop includes a condenser, expansion valve, evaporator and the compressors. A single sorbate loop can be employed for single-temperature-control such as air conditioning and heating. Two sorbate loops can be used for two-temperature-control as in a refrigerator and freezer. The evaporator temperatures control the freezer and refrigerator temperatures. Alternatively the refrigerator temperature can be cooled by the freezer with one sorbate loop. A heat transfer fluid is circulated in a closed loop which includes a radiator and the compressors. Low temperature heat is exhausted by the radiator. High temperature heat is added to the heat transfer fluid entering the compressors which are desorbing vapor. Heat is transferred from compressors which are sorbing vapor to the heat transfer fluid, and from the heat transfer fluid to the compressors which are desorbing vapor. Each compressor is subjected to the following phases, heating to its highest temperature, cooling down from its highest temperature, cooling to its lowest temperature, and warming up from its lowest temperature. The phases are repeated to complete a cycle and regenerate heat.

  17. Bipolar disorder: staging and neuroprogression

    Directory of Open Access Journals (Sweden)

    Rodrigues, Aline André

    2014-04-01

    Full Text Available In bipolar disorder illness progression has been associated with a higher number of mood episodes and hospitalizations, poorer response to treatment, and more severe cognitive and functional impairment. This supports the notion of the use of staging models in this illness. The value of staging models has long been recognized in many medical and malignant conditions. Staging models rely on the fact that different interventions may suit different stages of the disorder, and that better outcomes can be obtained if interventions are implemented earlier in the course of illness. Thus, treatment planning would benefit from the assessment of cognition, functioning and comorbidities. Staging may offer a means to refine treatment options, and most importantly, to establish a more precise diagnosis. Moreover, staging could have utility as course specifier and may guide treatment planning and better information to patients and their family members of what could be expected in terms of prognosis. The present study reviews the clinical and biological basis of the concept of illness progression in bipolar disorder.

  18. Facilitating career advancement for women in the Geosciences through the Earth Science Women's Network (ESWN)

    Science.gov (United States)

    Hastings, M. G.; Kontak, R.; Holloway, T.; Kogan, M.; Laursen, S. L.; Marin-Spiotta, E.; Steiner, A. L.; Wiedinmyer, C.

    2011-12-01

    The Earth Science Women's Network (ESWN) is a network of women geoscientists, many of who are in the early stages of their careers. The mission of ESWN is to promote career development, build community, provide informal mentoring and support, and facilitate professional collaborations, all towards making women successful in their scientific careers. ESWN currently connects over 1000 women across the globe, and includes graduate students, postdoctoral associates, faculty from a diversity of colleges and universities, program managers, and government, non-government and industry researchers. ESWN facilitates communication between its members via an email listserv and in-person networking events, and also provides resources to the broader community through the public Earth Science Jobs Listserv that hosts over 1800 subscribers. With funding from a NSF ADVANCE PAID grant, our primary goals include growing our membership to serve a wider section of the geosciences community, designing and administering career development workshops, promoting professional networking at major scientific conferences, and developing web resources to build connections, collaborations, and peer mentoring for and among women in the Earth Sciences. Recognizing that women in particular face a number of direct and indirect biases while navigating their careers, we aim to provide a range of opportunities for professional development that emphasize different skills at different stages of career. For example, ESWN-hosted mini-workshops at national scientific conferences have targeted skill building for early career researchers (e.g., postdocs, tenure-track faculty), with a recent focus on raising extramural research funding and best practices for publishing in the geosciences literature. More concentrated, multi-day professional development workshops are offered annually with varying themes such as Defining Your Research Identity and Building Leadership Skills for Success in Scientific Organizations

  19. Tryptophan degradation in women with breast cancer: a pilot study

    Directory of Open Access Journals (Sweden)

    Schubert Christine M

    2011-05-01

    Full Text Available Abstract Background Altered tryptophan metabolism and indoleamine 2,3-dioxygenase activity are linked to cancer development and progression. In addition, these biological factors have been associated with the development and severity of neuropsychiatric syndromes, including major depressive disorder. However, this biological mechanism associated with both poor disease outcomes and adverse neuropsychiatric symptoms has received little attention in women with breast cancer. Therefore, a pilot study was undertaken to compare levels of tryptophan and other proteins involved in tryptophan degradation in women with breast cancer to women without cancer, and secondarily, to examine levels in women with breast caner over the course of chemotherapy. Findings Blood samples were collected from women with a recent diagnosis of breast cancer (n = 33 before their first cycle of chemotherapy and after their last cycle of chemotherapy. The comparison group (n = 24 provided a blood sample prior to breast biopsy. Plasma concentrations of tryptophan, kynurenine, and tyrosine were determined. The kynurenine to tryptophan ratio (KYN/TRP was used to estimate indoleamine 2,3-dioxygenase activity. On average, the women with breast cancer had lower levels of tryptophan, elevated levels of kynurenine and tyrosine and an increased KYN/TRP ratio compared to women without breast cancer. There was a statistically significant difference between the two groups in the KYN/TRP ratio (p = 0.036, which remained elevated in women with breast cancer throughout the treatment trajectory. Conclusions The findings of this pilot study suggest that increased tryptophan degradation may occur in women with early-stage breast cancer. Given the multifactorial consequences of increased tryptophan degradation in cancer outcomes and neuropsychiatric symptom manifestation, this biological mechanism deserves broader attention in women with breast cancer.

  20. Platelet count can predict metabolic syndrome in older women.

    Science.gov (United States)

    Chen, Yen-Lin; Hung, Yi-Jen; He, Chih-Tsueng; Lee, Chien-Hsing; Hsiao, Fone-Ching; Pei, Dee; Hsieh, Chang-Hsun

    2015-01-01

    Platelet count (PC) has been found to be related to the metabolic syndrome (MetS). However, the role of PC on MetS remained unclear. In order to evaluate the relationship between PC and MetS components cross-sectionally and determine the optimal cutoff PCs for predicting the subsequent risk of MetS development with sex specificity, two stages included cross-sectional (stage 1) and prospective (stage 2) cohort study were conducted. Stage 1 involved 10 579 subjects aged ≥60 years, of which 7718 subjects advanced to stage 2 with a mean 3.8 year follow-up were enrolled. The MetS components and PC were determined. The PC cutoffs for higher chances of developing MetS in stage 1 were calculated using receiver operating characteristic (ROC) curve analyses. In stage 2, non-MetS subjects were classified into high-PC (HPC) and low-PC (LPC) groups according to the cutoff values from stage 1. We examined the difference of future MetS incidence and calculated the odds ratio (OR) between these two groups. In stage 1, multiple regression showed that age and triglyceride (both sexes) and waist circumstance and high-density lipoprotein cholesterol (only women) were independently correlated with PC. There was significant difference in the area under the ROC curve (AUC) only of HPC women, which exceeded the standard curve (AUC = 0.542, p women had an OR of 1.287 (95% confidence interval: 1.135-1.461) of developing MetS after 3.8 years. The Kaplan-Meier curve demonstrated a higher incidence of MetS development in HPC women. In conclusion, our results suggest that PC was associated with MetS with sex effects. Most of the MetS components were independent factors for increasing PC, and the risk for subsequent development of MetS was noted when PC >223 × 10(3)/μl in elderly women.