WorldWideScience

Sample records for clearpet tm prototype

  1. Validation of GEANT3 simulation studies with a dual-head PMT ClearPET TM prototype

    CERN Document Server

    Ziemons, K; Streun, M; Pietrzyk, U

    2004-01-01

    The ClearPET TM project is proposed by working groups of the Crystal Clear Collaboration (CCC) to develop a 2/sup nd/ generation high performance small animal positron emission tomograph (PET). High sensitivity and high spatial resolution is foreseen for the ClearPET TM camera by using a phoswich arrangement combining mixed lutetium yttrium aluminum perovskite (LuYAP:Ce) and lutetium oxyorthosilicate (LSO) scintillating crystals. Design optimizations for the first photomultiplier tube (PMT) based ClearPET camera are done with a Monte-Carlo simulation package implemented on GEANT3 (CERN, Geneva, Switzerland). A dual-head prototype has been built to test the frontend electronics and was used to validate the implementation of the GEANT3 simulation tool. Multiple simulations were performed following the experimental protocols to measure the intrinsic resolution and the sensitivity profile in axial and radial direction. Including a mean energy resolution of about 27.0% the simulated intrinsic resolution is about (...

  2. Study of electroless nickel plating on PerFactoryTM rapid prototype model

    OpenAIRE

    J.C. Rajaguru; C. Au, M. Duke

    2012-01-01

    This paper presents an investigation of electroless nickel plating on PerFactoryTM rapid prototype model built on PerFactoryTM R05 material. PerFactoryTM R05 is acrylic based photo sensitive resin. It is a popular material in rapid prototyping using PerFactoryTM method which employs addictive manufacturing technique to build prototypes for visual inspection, assembly etc. Metallization of such a prototype can extend the application envelop of the rapid prototyping technique as they can be use...

  3. Study of electroless nickel plating on PerFactoryTM rapid prototype model

    Directory of Open Access Journals (Sweden)

    J.C. Rajaguru

    2012-12-01

    Full Text Available This paper presents an investigation of electroless nickel plating on PerFactoryTM rapid prototype model built on PerFactoryTM R05 material. PerFactoryTM R05 is acrylic based photo sensitive resin. It is a popular material in rapid prototyping using PerFactoryTM method which employs addictive manufacturing technique to build prototypes for visual inspection, assembly etc. Metallization of such a prototype can extend the application envelop of the rapid prototyping technique as they can be used in many functional applications. Unlike the electroless nickel plating on metal substrate, the process on acrylic resin substrate is not auto-catalytic. Hence, etching and activation are necessary for initiating the process. The final coating is then investigated using scanning electron microscope (SEM together with energy dispersive spectroscopy (EDS and x-ray diffraction (XRD analysis to identify the morphology and structure of the coating. The SEM & EDS analysis on surface and chemical composition of model surface after each preliminary surface treatment are also presented. Finally the layer is tested on Vickers micro hardness tester.

  4. Development of a static bioactive stent prototype and dynamic aneurysm-on-a-chip(TM) model for the treatment of aneurysms

    Science.gov (United States)

    Reece, Lisa M.

    Aneurysms are pockets of blood that collect outside blood vessel walls forming dilatations and leaving arterial walls very prone to rupture. Current treatments include: (1) clipping, and (2) coil embolization, including stent-assisted coiling. While these procedures can be effective, it would be advantageous to design a biologically active stent, modified with magnetic stent coatings, allowing cells to be manipulated to heal the arterial lining. Further, velocity, pressure, and wall shear stresses aid in the disease development of aneurysmal growth, but the shear force mechanisms effecting wound closure is elusive. Due to these factors, there is a definite need to cultivate a new stent device that will aid in healing an aneurysm in situ. To this end, a static bioactive stent device was synthesized. Additionally, to study aneurysm pathogenesis, a lab-on-a-chip device (a dynamic stent device) is the key to discovering the underlying mechanisms of these lesions. A first step to the reality of a true bioactive stent involves the study of cells that can be tested against the biomaterials that constitute the stent itself. The second step is to test particles/cells in a microfluidic environment. Therefore, biocompatability data was collected against PDMS, bacterial nanocellulose (BNC), and magnetic bacterial nanocellulose (MBNC). Preliminary static bioactive stents were synthesized whereby BNC was grown to cover standard nitinol stents. In an offshoot of the original research, a two-dimensional microfluidic model, the Aneurysm-on-a-ChipTM (AOC), was the logical answer to study particle flow within an aneurysm "sac" - this was the dynamic bioactive stent device. The AOC apparatus can track particles/cells when it is coupled to a particle image velocimetry software (PIV) package. The AOC fluid flow was visualized using standard microscopy techniques with commercial microparticles/cells. Movies were taken during fluid flow experiments and PIV was utilized to monitor.

  5. tmRDB (tmRNA database)

    DEFF Research Database (Denmark)

    Zwieb, Christian; Gorodkin, Jan; Knudsen, Bjarne;

    2003-01-01

    Maintained at the University of Texas Health Science Center at Tyler, Texas, the tmRNA database (tmRDB) is accessible at the URL http://psyche.uthct.edu/dbs/tmRDB/tmRDB.html with mirror sites located at Auburn University, Auburn, Alabama (http://www.ag.auburn.edu/mirror/tm......RDB/) and the Bioinformatics Research Center, Aarhus, Denmark (http://www.bioinf.au.dk/tmRDB/). The tmRDB collects and distributes information relevant to the study of tmRNA. In trans-translation, this molecule combines properties of tRNA and mRNA and binds several proteins to form the tmRNP. Related RNPs are likely...... to be functional in all bacteria. In this release of tmRDB, 186 new entries from 10 bacterial groups for a total of 274 tmRNA sequences have been added. Lists of the tmRNAs and the corresponding tmRNA-encoded tag-peptides are presented in alphabetical and phylogenetic order. The tmRNA sequences are aligned...

  6. Studies oriented to optimize the image quality of the small animal PET: Clear PET, modifying some of the parameters of the reconstruction algorithm IMF-OSEM 3D on the data acquisition simulated with GAMOS; Estudios para la optimizaciOn de la calidad de imagen en el escaner ClearPET, modifi cando parametros del algoritmo IMF-OSEM 3D sobre adquisiciones simuladas con GAMOS

    Energy Technology Data Exchange (ETDEWEB)

    Canadas, M.; Mendoza, J.; Embid, M.

    2007-09-27

    This report presents studies oriented to optimize the image quality of the small animal PET: Clear- PET. Certain figures of merit (FOM) were used to assess a quantitative value of the contrast and delectability of lesions. The optimization was carried out modifying some of the parameters in the reconstruction software of the scanner, imaging a mini-Derenzo phantom and a cylinder phantom with background activity and two hot spheres. Specifically, it was evaluated the incidence of the inter-update Metz filter (IMF) inside the iterative reconstruction algorithm 3D OSEM. The data acquisition was simulated using the GAMOS framework (Monte Carlo simulation). Integrating GAMOS output with the reconstruction software of the scanner was an additional novelty of this work, to achieve this, data sets were written with the list-mode format (LMF) of ClearPET. In order to verify the optimum values obtained, we foresee to make real acquisitions in the ClearPET of CIEMAT. (Author) 17 refs.

  7. Architectural prototyping

    DEFF Research Database (Denmark)

    Bardram, Jakob Eyvind; Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2004-01-01

    A major part of software architecture design is learning how specific architectural designs balance the concerns of stakeholders. We explore the notion of "architectural prototypes", correspondingly architectural prototyping, as a means of using executable prototypes to investigate stakeholders......' concerns with respect to a system under development. An architectural prototype is primarily a learning and communication vehicle used to explore and experiment with alternative architectural styles, features, and patterns in order to balance different architectural qualities. The use of architectural...... prototypes in the development process is discussed, and we argue that such prototypes can play a role throughout the entire process. The use of architectural prototypes is illustrated by three distinct cases of creating software systems. We argue that architectural prototyping can provide key insights...

  8. Architectural Prototyping

    DEFF Research Database (Denmark)

    Bardram, Jakob; Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2004-01-01

    A major part of software architecture design is learning how specific architectural designs balance the concerns of stakeholders. We explore the notion of "architectural prototypes", correspondingly architectural prototyping, as a means of using executable prototypes to investigate stakeholders......' concerns with respect to a system under development. An architectural prototype is primarily a learning and communication vehicle used to explore and experiment with alternative architectural styles, features, and patterns in order to balance different architectural qualities. The use of architectural...... prototypes in the development process is discussed, and we argue that such prototypes can play a role throughout the entire process. The use of architectural prototypes is illustrated by three distinct cases of creating software systems. We argue that architectural prototyping can provide key insights...

  9. Collaborative Prototyping

    DEFF Research Database (Denmark)

    Bogers, Marcel; Horst, Willem

    2014-01-01

    processes. Our analysis reveals two levels of prototyping. Besides the more formal managerial level, we identify the informal designer level, where the actual practice of prototyping takes place. On this level, collaborative prototyping transforms the act of prototyping from an activity belonging...... changes, and it detects emerging usability problems through active engagement and experimentation. As such, the collaborative prototype acts as a boundary object to represent, understand, and transform knowledge across functional, hierarchical, and organizational boundaries. Our study also identifies some...... constraints in involving the appropriate stakeholders at the right time. The paper specifically elaborates on the role of users in collaborative prototyping, which is important in order to cover all phases of the problem-solving cycle but triggers an interesting challenge due to the “reverse empathy...

  10. Prototyping Revisited

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Hansen, Svend Aage; Hansen, Erik

    2006-01-01

    Until now, prototyping has been developing as a technological discipline. In so it has proven to be a strong means to test specific solutions or physical designs before the launch of a product. The results have been reduced development time and improvement of quality in a broad sense. There are......, however, indications that we should review our perception of prototypes to be broader and to view our application of prototypes in a broader organizational view. This paper presents an initial and explorative review of the changing role of prototypes in product development....

  11. On the 161Tm, 163Tm, 165Tm decay

    International Nuclear Information System (INIS)

    For the purpose of obtaining data on 161Er, 163Er and 165Er nuclear level properties the 161Tm→161Er, 163Tm→163Er, 165Tm→165Er decay is investigated. Radioactive isotopes sup(161, 163, 165)Tm have been obtained in the deep fission reaction at the tantalum target irradiation during 1-10 h by 660 MeV protons. The electron spectra of internal conversion have been investigated by beta spectrographs with constant magnetic field. Gamma radiation spectra have been measured by means of precision gamma spectrometers with Ge(Li) detectors. Measurement results in the gamma radiation energy range from 5 to 400 keV are tabulated. Gamma radiation and conversion electron energies and intensities are specified. 68 gamma transitions are related to 161Tm decay. For 67 of them multipolarity types are determined, for 20 - coefficients of multipolarity mixture. 47 gamma transitions have been found at the 163Tm decay. New gamma transitions with energies of 14.72(E1), 20.34(E2) and 35.05 KeV have been found out. Coefficients of multipolarity mixture are obtained for 18 gamma transitions. 82 gamma transitions have been found out at the 165Tm decay. 13 gamma transitions have been observed for the first time. 60 gamma transition multipolarities are determined. Coefficients of multipolarity mixture are calculated for 19 gamma transitions. Coefficients of multipolarity mixture are obtained from the intensity ratio of L1-, L2-, L3-, M1-, M2-, M3-lines

  12. Unikabeton Prototype

    DEFF Research Database (Denmark)

    Dombernowsky, Per; Søndergaard, Asbjørn

    2011-01-01

    The Unikabeton prototype structure was developed as the finalization of the cross-disciplinary research project Unikabeton, exploring the architectural potential in linking the computational process of topology optimisation with robot fabrication of concrete casting moulds. The project was elabor...... of Architecture was to develop a series of optimisation experiments, concluding in the design and optimisation of a full scale prototype concrete structure.......The Unikabeton prototype structure was developed as the finalization of the cross-disciplinary research project Unikabeton, exploring the architectural potential in linking the computational process of topology optimisation with robot fabrication of concrete casting moulds. The project...

  13. Solution Prototype

    DEFF Research Database (Denmark)

    Efeoglu, Arkin; Møller, Charles; Serie, Michel

    2013-01-01

    This paper outlines an artifact building and evaluation proposal. Design Science Research (DSR) studies usually consider encapsulated artifact that have relationships with other artifacts. The solution prototype as a composed artifact demands for a more comprehensive consideration in its systemat...

  14. LibQUAL+TM

    OpenAIRE

    Cook, Colleen; Heath, Fred

    2006-01-01

    LibQUAL+(tm) is a suite of services that libraries use to solicit, track, understand, and act upon users' opinions of service quality. These services are offered to the library community by the Association of Research Libraries (ARL). The program's centerpiece is a rigorously tested Web-based survey bundled with training that helps libraries assess and improve library services, change organizational culture, and market the library. The goals of LibQUAL+(TM) are to: Foster a culture of exc...

  15. A One-Piece Lunar Regolith Bag Garage Prototype

    Science.gov (United States)

    Smithers, G. A.; Nehls, M. K.; Hovater, M. A.; Evans, S. W.; Miller, J. S.; Broughton, R. M., Jr.; Beale, D.; Kilinc-Balci, F.

    2007-01-01

    Shelter structures on the moon, even in early phases of exploration, should incorporate lunar materials as much as possible. This Technical Memorandum details the design and construction of a prototype for a one-piece regolith bag unpressurized garage concept and a materials testing program to investigate six candidate fabrics to learn how they might perform in the lunar environment. The conceptualization was that a lightweight fabric form be launched from Earth and landed on the lunar surface to be robotically filled with raw lunar regolith. Regolith bag fabric candidates included: Vectran(TM), Nextel(TM), Gore PTFE Fabric(TM), Zylon(TM), Twaron(TM), and Nomex(TM). Tensile (including post radiation exposure), fold, abrasion, and hypervelocity impact testing were performed under ambient conditions, and also performed under cold and elevated temperatures. In some cases, Johnson Space Center lunar simulant (JSC-1) was used in conjunction with testing. A series of preliminary structures was constructed during final prototype design based on the principles of the classic masonry arch. The prototype was constructed of Kevlar(TM) and filled with vermiculite. The structure is free-standing, but has not yet been load tested. Future plans would be to construct higher fidelity prototypes and to conduct appropriate tests of the structure.

  16. TM4Book: Visualization transforms

    DEFF Research Database (Denmark)

    2011-01-01

    XSLT-scripts til visualisering af semantiske strukturer i teksteditoren TM4Book: plot, storyline og timeline......XSLT-scripts til visualisering af semantiske strukturer i teksteditoren TM4Book: plot, storyline og timeline...

  17. 75 FR 5068 - Lock + TM

    Science.gov (United States)

    2010-02-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Lock + \\TM\\ Hydro Friends Fund XXXIII, LLC; Notice of Preliminary Permit... January 22, 2010. On January 8, 2010, Lock + \\TM\\ Hydro Friends Fund XXXIII, LLC (Lock + Hydro) filed...

  18. 75 FR 5071 - Lock + TM

    Science.gov (United States)

    2010-02-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Lock + \\TM\\ Hydro Friends Fund XXXI, LLC; Notice of Preliminary Permit... January 22, 2010. On January 8, 2010, Lock + \\TM\\ Hydro Friends Fund XXXI, LLC (Lock + Hydro) filed...

  19. Translation-Memory (TM) Research

    DEFF Research Database (Denmark)

    Schjoldager, Anne Gram; Christensen, Tina Paulsen

    2010-01-01

      It is no exaggeration to say that the advent of translation-memory (TM) systems in the translation profession has led to drastic changes in translators' processes and workflow, and yet, though many professional translators nowadays depend on some form of TM system, this has not been the object...... of much research. Our paper attempts to find out what we know about the nature, applications and influences of TM technology, including translators' interaction with TMs, and also how we know it. An essential part of the analysis is based on a selection of empirical TM studies, which we assume...... to be representative of the research field as a whole. Our analysis suggests that, while considerable knowledge is available about the technical side of TMs, more research is needed to understand how translators interact with TM technology and how TMs influence translators' cognitive translation processes....

  20. Virally encoded 7TM receptors

    DEFF Research Database (Denmark)

    Rosenkilde, M M; Waldhoer, M; Lüttichau, H R;

    2001-01-01

    A number of herpes- and poxviruses encode 7TM G-protein coupled receptors most of which clearly are derived from their host chemokine system as well as induce high expression of certain 7TM receptors in the infected cells. The receptors appear to be exploited by the virus for either immune evasion...... expression of this single gene in certain lymphocyte cell lineages leads to the development of lesions which are remarkably similar to Kaposi's sarcoma, a human herpesvirus 8 associated disease. Thus, this and other virally encoded 7TM receptors appear to be attractive future drug targets....

  1. Architectures of prototypes and architectural prototyping

    DEFF Research Database (Denmark)

    Hansen, Klaus Marius; Christensen, Michael; Sandvad, Elmer;

    1998-01-01

    This paper reports from experience obtained through development of a prototype of a global customer service system in a project involving a large shipping company and a university research group. The research group had no previous knowledge of the complex business of shipping and had never worked...... together as a team, but developed a prototype that more than fulfilled the expectations of the shipping company. The prototype should: - complete the first major phase within 10 weeks, - be highly vertical illustrating future work practice, - continuously live up to new requirements from prototyping...... constraints. Specifically allowing explicit restructuring phases when the architecture became problematic showed to be crucial.  ...

  2. A One-Piece Lunar Regolith-Bag Garage Prototype

    Science.gov (United States)

    Smithers, Gweneth A.; Nehls, Mary K.; Hovater, Mary A.; Evans, Steven W.; Miller, J. Scott; Broughton, Roy M.; Beale, David; Killing-Balci, Fatma

    2007-01-01

    Shelter structures on the moon, even in early phases of exploration, should incorporate lunar materials as much as possible. We designed and constructed a prototype for a one-piece regolith-bag unpressurized garage concept, and, in parallel, we conducted a materials testing program to investigate six candidate fabrics to learn how they might perform in the lunar environment. In our concept, a lightweight fabric form is launched from Earth to be landed on the lunar surface and robotically filled with raw lunar regolith. In the materials testing program, regolith-bag fabric candidates included: Vectran(TM), Nextel(TM), Gore PTFE Fabric(TM), Zylon(TM), Twaron(TM), and Nomex(TM). Tensile (including post radiation exposure), fold, abrasion, and hypervelocity impact testing were performed under ambient conditions, and, within our current means, we also performed these tests under cold and elevated temperatures. In some cases, lunar simulant (JSC-1) was used in conjunction with testing. Our ambition is to continuously refine our testing to reach lunar environmental conditions to the extent possible. A series of preliminary structures were constructed during design of the final prototype. Design is based on the principles of the classic masonry arch. The prototype was constructed of Kevlar(TM) and filled with vermiculite (fairly close to the weight of lunar regolith on the moon). The structure is free-standing, but has not yet been load tested. Our plan for the future would be to construct higher fidelity mockups with each iteration, and to conduct appropriate tests of the structure.

  3. Rethink! prototyping transdisciplinary concepts of prototyping

    CERN Document Server

    Nagy, Emilia; Stark, Rainer

    2016-01-01

    In this book, the authors describe the findings derived from interaction and cooperation between scientific actors employing diverse practices. They reflect on distinct prototyping concepts and examine the transformation of development culture in their fusion to hybrid approaches and solutions. The products of tomorrow are going to be multifunctional, interactive systems – and already are to some degree today. Collaboration across multiple disciplines is the only way to grasp their complexity in design concepts. This underscores the importance of reconsidering the prototyping process for the development of these systems, particularly in transdisciplinary research teams. “Rethinking Prototyping – new hybrid concepts for prototyping” was a transdisciplinary project that took up this challenge. The aim of this programmatic rethinking was to come up with a general concept of prototyping by combining innovative prototyping concepts, which had been researched and developed in three sub-projects: “Hybrid P...

  4. Listening and Legos[TM

    Science.gov (United States)

    Morris, Pamela

    2012-01-01

    This simple exercise, performed in teams, gives students practice in listening to instructions, particularly when there are restrictions for the communication. The teams compete in a limited amount of time to build a Lego[TM] structure based on the instructions of one team member. Which team listens the best and is most successful?

  5. 75 FR 78234 - Lock+TM

    Science.gov (United States)

    2010-12-15

    ...; Project No. 13786-000] Lock+ TM Hydro Friends Fund XXXIV; FFP Missouri 5, LLC; Solia 2 Hydroelectric, LLC... proposed Emsworth Lock and Dam Projects: Lock+ TM Hydro Friends Fund XXXIV's proposed project (Project...

  6. Structural and Functional Importance of Transmembrane Domain 3 (TM3) in the Aspartate:Alanine Antiporter AspT: Topology and Function of the Residues of TM3 and Oligomerization of AspT▿

    OpenAIRE

    Nanatani, Kei; Maloney, Peter C.; Abe, Keietsu

    2009-01-01

    AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, a membrane protein of 543 amino acids with 10 putative transmembrane (TM) helices, is the prototype of the aspartate:alanine exchanger (AAE) family of transporters. Because TM3 (isoleucine 64 to methionine 85) has many amino acid residues that are conserved among members of the AAE family and because TM3 contains two charged residues and four polar residues, it is thought to be located near (or to form part of) the substrat...

  7. 75 FR 78236 - Lock+TM

    Science.gov (United States)

    2010-12-15

    ... Energy Regulatory Commission Lock+\\TM\\ Hydro Friends Fund XLVII, FFP Missouri 16, LLC, et al.; Notice of... Intervene December 8, 2010. Lock+\\TM\\ Hydro Friends Fund XLVII........ Project No. 13743-000. FFP Missouri.... Descriptions of the proposed Opekiska Lock and Dam Projects: Lock+\\TM\\ Hydro Friends Fund XLVII's...

  8. 75 FR 2129 - Lock+TM

    Science.gov (United States)

    2010-01-14

    ... Energy Regulatory Commission Lock+ TM Hydro Friends Fund XXX, LLC; Notice of Preliminary Permit... January 6, 2010. On November 13, 2009, Lock+ TM Hydro Friends Fund XXX, LLC filed an application, pursuant...,018 megawatt-hours. Applicant Contact: Wayne F. Krouse, Lock+ TM Hydro Friends Fund XXX, LLC,...

  9. Fabrication and Prototyping Lab

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The Fabrication and Prototyping Lab for composite structures provides a wide variety of fabrication capabilities critical to enabling hands-on research and...

  10. Rapid Prototyping Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The ARDEC Rapid Prototyping (RP) Laboratory was established in December 1992 to provide low cost RP capabilities to the ARDEC engineering community. The Stratasys,...

  11. Design, construction, and field mapping of the HISTRAP prototype dipole

    Energy Technology Data Exchange (ETDEWEB)

    Tatum, B.A.; Dowling, D.T.; Lord, R.S.; Mosko, S.W.; Olsen, D.K.

    1989-01-01

    HISTRAP is a proposed 2.67 T-m synchrotron-cooler-storage ring having eight 45/degree/, C-design dipole magnets. A prototype dipole has been designed, fabricated, and mapped. The magnet design utilizes curved and angled coil ends to compensate for end effects in the field. Construction of the prototype dipole has been completed by the FNAL magnet factory. The magnetic field has been mapped using a Hall-effect probe afixed to a newly constructed, PC-based, horizontal positioning system. Results of the field mapping are presented. 6 refs., 7 figs., 1 tabs.

  12. Analysis and Function of Prototype Foamy Virus Envelope N Glycosylation

    OpenAIRE

    Lüftenegger, Daniel; Picard-Maureau, Marcus; Stanke, Nicole; Rethwilm, Axel; Lindemann, Dirk

    2005-01-01

    The prototype foamy virus (PFV) glycoprotein, which is essential for PFV particle release, displays a highly unusual biosynthesis, resulting in posttranslational cleavage of the precursor protein into three particle-associated subunits, i.e., leader peptide (LP), surface (SU), and transmembrane (TM). Glycosidase digestion of metabolically labeled PFV particles revealed the presence of N-linked carbohydrates on all subunits. The differential sensitivity to specific glycosidases indicated that ...

  13. Prototype energy-saving motor; Prototyp Energiesparmotor

    Energy Technology Data Exchange (ETDEWEB)

    Weingartner, J. [Baechli AG, Kriens-Obernau (Switzerland); Lindegger, M. [Circle Motor AG, Guemligen (Switzerland)

    2004-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) presents the results of investigations made on the development of an energy-efficient electric motor. The aim of the prototype 'Eco-Motor' project was the development of a winding technique and the optimisation of the design of the stator. Various winding techniques (toroid winding, core winding, coil winding) were examined and used in the realisation of prototype 'Eco-Motors' for a nominal voltage of 230 V a.c. The designs were evaluated in both a simulation (FEMM) and as well as in the test facilities at the College of Engineering and Architecture in Lucerne, Switzerland. The measured data of the 'Eco-Motor' were then compared with a standard asynchronous motor. The 'Eco-Motor' with a toroid winding had the best efficiency. At low loads, all 'Eco-Motor' prototypes have a higher efficiency than asynchronous motors. On the other hand, none of the 'Eco-Motors' have yet reached the nominal power of 250 W. The developers state, however, that with a few adjustments this should pose no problems.

  14. First results on prototype production of new LuYAP crystals

    CERN Document Server

    Annenkov, A N; Korzhik, M; Lecoq, P; Missevitch, O V

    2004-01-01

    A small animal positron emission tomograph, ClearPET, is under development by the Crystal Clear Collaboration at CERN. ClearPET, a detector with Depth Of Interaction (DOI) determination capability is based on LSO:Ce and (Lu //0//.//7-Y//0//.//3)AlO//3:Ce ((Lu-Y)AP:Ce or LuYAP) scintillation crystals assembled in two-layer matrix with PMT readout. The key point of the ClearPET challenge was the development of the mass production technology of Lu-based scintillation crystals with perovskite structure. The LuYAP scintillation crystal has been proposed several years ago but its mass production technology could only be managed now, through tremendous efforts of the Crystal Clear Collaboration and of its industrial partners. Crystal ingots 18-25mm in diameter and 170-210mm in length are available now. In this paper, we discuss the results of the crystal mass production technology development and its application in detecting modules.

  15. Cooperative Prototyping Experiments

    DEFF Research Database (Denmark)

    Bødker, Susanne; Grønbæk, Kaj

    1989-01-01

    This paper describes experiments with a design technique that we denote cooperative prototyping. The experiments consider design of a patient case record system for municipal dental clinics in which we used HyperCard, an off the shelf programming environment for the Macintosh. In the ecperiments we...... tried to achieve a fluent work-like evaluation of prototypes where users envisioned future work with a computer tool, at the same time as we made on-line modifications of prototypes in cooperation with the users when breakdown occur in their work-like evaluation. The experiments showed...... these experiences we discuss problems in the process, requirements for design tools, and issues involved in getting going with cooperative prototyping with active user involvement....

  16. Ceramic subsurface marker prototypes

    Energy Technology Data Exchange (ETDEWEB)

    Lukens, C.E. [Rockwell International Corp., Richland, WA (United States). Rockwell Hanford Operations

    1985-05-02

    The client submitted 5 sets of porcelain and stoneware subsurface (radioactive site) marker prototypes (31 markers each set). The following were determined: compressive strength, thermal shock resistance, thermal crazing resistance, alkali resistance, color retention, and chemical resistance.

  17. The TM3270 Media-processor

    NARCIS (Netherlands)

    van de Waerdt, J.W.

    2006-01-01

    I n this thesis, we present the TM3270 VLIW media-processor, the latest of TriMedia processors, and describe the innovations with respect to its prede- cessor: the TM3260. We describe enhancements to the load/store unit design, such as a new data prefetching technique, and architectural enhancements

  18. 75 FR 78233 - Lock+TM

    Science.gov (United States)

    2010-12-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Lock+\\TM\\ Hydro Friends Fund XXXVII; FFP Missouri 6, LLC; Solia 1.... Descriptions of the proposed Emsworth Back Channel Dam Projects: Lock+ TM Hydro Friends Fund XXXVII's...

  19. Magnetic ordering in TmGa

    DEFF Research Database (Denmark)

    Cadogan, J.M.; Stewart, G.A.; Muños Pérez, S.;

    2014-01-01

    We have determined the magnetic structure of the intermetallic compound TmGa by high-resolution neutron powder diffraction and 169Tm Mössbauer spectroscopy. This compound crystallizes in the orthorhombic (Cmcm) CrB-type structure and its magnetic structure is characterized by magnetic order of th...

  20. The tmRDB and SRPDB resources

    DEFF Research Database (Denmark)

    Andersen, Ebbe Sloth; Rosenblad, Magnus Alm; Larsen, Niels;

    2006-01-01

    Maintained at the University of Texas Health Science Center at Tyler, Texas, the tmRNA database (tmRDB) is accessible at the URL http://psyche.uthct.edu/dbs/tmRDB/tmRDB.html with mirror sites located at Auburn University, Auburn, Alabama (http://www.ag.auburn.edu/mirror/tmRDB/) and the Royal...... in investigations of the tmRNP (a ribonucleoprotein complex which liberates stalled bacterial ribosomes) and the SRP (a particle which recognizes signal sequences and directs secretory proteins to cell membranes). The curated tmRNA and SRP RNA alignments consider base pairs supported by comparative sequence...... analysis. Also shown are alignments of the tmRNA-associated proteins SmpB, ribosomal protein S1, alanyl-tRNA synthetase and Elongation Factor Tu, as well as the SRP proteins SRP9, SRP14, SRP19, SRP21, SRP54 (Ffh), SRP68, SRP72, cpSRP43, Flhf, SRP receptor (alpha) and SRP receptor (beta). All alignments can...

  1. Prototyping a Smart City

    DEFF Research Database (Denmark)

    Korsgaard, Henrik; Brynskov, Martin

    In this paper, we argue that by approaching the so-called Smart City as a design challenge, and an interaction design perspective, it is possible to both uncover existing challenges in the interplay between people, technology and society, as well as prototype possible futures. We present a case i...... in which we exposed data about the online communication between the citizens and the municipality on a highly visible media facade, while at the same time prototyped a tool that enabled citizens to report ‘bugs’ within the city....

  2. Micro-Fuel Cells{sup TM} for portable electronics

    Energy Technology Data Exchange (ETDEWEB)

    Hockaday, R.G.; DeJohn, M.; Navas, C.; Turner, P.S.; Vaz, H.L.; Vazul, L.L. [Energy Related Devices Inc., Los Alamos, NM (United States)

    2000-05-01

    The Micro-Fuel Cell{sup TM} is a new power supply which provides a superior alternative compared to rechargeable batteries. A prototype has been developed by Manhattan Scientifics Inc. in collaboration with Energy Related Devices Inc. This mass-producible high-energy power supply can be used for cellular telephones, portable computers and other portable devices. Instead of being recharged, it can be easily refueled with methanol. The approach taken in designing this product was to develop a competitive product with definite advantages over existing products. The Micro-Fuel Cell{sup TM} is based on the idea that a fuel cell can be built onto an engineered microplastic substrate. In this case, the integrated design makes use of thin film vacuum deposition techniques to coat patterned, etched-nuclear-particle-track plastic membranes. This process forms catalytically active surface area electrodes on either side of a single structured proton-exchange-membrane electrolyte. Methanol was the choice fuel for this system because compared to hydrogen and metal hydrides, it was considered to be safer and more compact. In addition, the theoretical specific energy of methanol is significantly higher than for lithium-ion batteries. The problem of crossover, whereby methanol fuel diffuses across the fuel cell from the anode to the cathode, has also been solved by using a selectively permeable membrane. 5 refs., 4 figs.

  3. AGS Booster prototype magnets

    Energy Technology Data Exchange (ETDEWEB)

    Danby, G.; Jackson, J.; Lee, Y.Y.; Phillips, R.; Brodowski, J.; Jablonski, E.; Keohane, G.; McDowell, B.; Rodger, E.

    1987-03-19

    Prototype magnets have been designed and constructed for two half cells of the AGS Booster. The lattice requires 2.4m long dipoles, each curved by 10/sup 0/. The multi-use Booster injector requires several very different standard magnet cycles, capable of instantaneous interchange using computer control from dc up to 10 Hz.

  4. LEP vacuum chamber, prototype

    CERN Multimedia

    1983-01-01

    Final prototype for the LEP vacuum chamber, see 8305170 for more details. Here we see the strips of the NEG pump, providing "distributed pumping". The strips are made from a Zr-Ti-Fe alloy. By passing an electrical current, they were heated to 700 deg C.

  5. Prototype ATLAS straw tracker

    CERN Multimedia

    Laurent Guiraud

    1998-01-01

    This is an early prototype of the straw tracking device for the ATLAS detector at CERN. This detector will be part of the LHC project, scheduled to start operation in 2008. The straw tracker will consist of thousands of gas-filled straws, each containing a wire, allowing the tracks of particles to be followed.

  6. Surrogates-based prototyping

    NARCIS (Netherlands)

    Du Bois, E.; Horvath, I.

    2014-01-01

    The research is situated in the system development phase of interactive software products. In this detailed design phase, we found a need for fast testable prototyping to achieve qualitative change proposals on the system design. In this paper, we discuss a literature study on current software devel

  7. Ignitor Prototype Construction Program

    Science.gov (United States)

    Galas-So, G.; Lanzavecchia, L.; Dalmut, G.; Dra-Go, G.; Laurenti, A.; Marabotto, R.; Ghia, G.; Munaro, G.; Pirozzi, M.; Destefanis, L.; Andreani, R.; Crescenzi, C.; Cucchiaro, A.; Gasparotto, M.; Pizzuto, A.; Coppi, B.

    1997-11-01

    The design solutions adopted for Ignitor have been validated by a comprehensive engineering R&D program. The prototype construction program has been conducted by the industrial Consortium CITIF (ANSALDO and FIAT, with ABB as the main subcontractor). The manufacturing of full size prototypes of the most important components of the machine as well as tests on the adopted materials and on critical component interfaces have been carried out and have provided all the information necessary to continue the construction of the machine with the necessary confidence. In particular, an extensive test program has been launched to identify the mechanical properties of the ETP cold rolled copper plates produced for the toroidal field magnet. Tests under combined compressive/shear loads to evaluate the copper-insulation bonding shear strength have given positive results.

  8. Ghana Watershed Prototype Products

    Science.gov (United States)

    ,

    2007-01-01

    Introduction/Background A number of satellite data sets are available through the U.S. Geological Survey (USGS) for monitoring land surface features. Representative data sets include Landsat, Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER), and Shuttle Radar Topography Mission (SRTM). The Ghana Watershed Prototype Products cover an area within southern Ghana, Africa, and include examples of the aforementioned data sets along with sample SRTM derivative data sets.

  9. Radiotherapy and Antiangiogenic TM in Lung Cancer

    Directory of Open Access Journals (Sweden)

    Mohamed K. Khan

    2002-01-01

    Full Text Available Tetrathiomolybdate (TM is a potent nontoxic orally delivered copper complexing agent under development for the last several years for the treatment of Wilson's disease. It has been shown to block angiogenesis in primary and metastatic tumors. Therefore, the combination of cytotoxic radiotherapy (RT and antiangiogenic TM could target both the existing tumor and the tumor microvasculature in a comprehensive strategy. Using a Lewis lung high metastatic (LLHM carcinoma mouse tumor model, we demonstrate that the combination of TM and RT is more effective than either used as monotherapy. We also show that their therapeutic effects are additive, with no additional toxicity. We show that TM has no significant cytotoxicity in vitro against LLHM tumor cells, further supporting the antiangiogenic mechanism for its action.

  10. VentureStar(tm) Payload Processing Concept

    Science.gov (United States)

    Sharp, Susan

    1998-01-01

    The philosophy and the operations concept of the VentureStar(tm) payload processing system is presented. The goal of VentureStar(tm) operations is to provide low cost access to space. This is to be achieved through the design of the vehicle, and operability of the ground system. Specifically, this is to be accomplished through rapid turnaround cycles, increased launch rate, high system reliability and availability and reduced required operations personnel. This is presented in viewgraph format.

  11. Rapid prototyping and time compression

    OpenAIRE

    Chatwin, Chris

    2000-01-01

    Rapid Prototyping - manufacture by layering processes: Stereolithography Selective Layer Sintering (SLS) Laminated Object Manufacture (LOM) Solid Ground Curing Small batch programmable rapid manufacture with lasers Micro-Engineering – Prototyping and Manufacture Additive - fabrication Subtractive – machining

  12. MITRE sensor layer prototype

    Science.gov (United States)

    Duff, Francis; McGarry, Donald; Zasada, David; Foote, Scott

    2009-05-01

    The MITRE Sensor Layer Prototype is an initial design effort to enable every sensor to help create new capabilities through collaborative data sharing. By making both upstream (raw) and downstream (processed) sensor data visible, users can access the specific level, type, and quantities of data needed to create new data products that were never anticipated by the original designers of the individual sensors. The major characteristic that sets sensor data services apart from typical enterprise services is the volume (on the order of multiple terabytes) of raw data that can be generated by most sensors. Traditional tightly coupled processing approaches extract pre-determined information from the incoming raw sensor data, format it, and send it to predetermined users. The community is rapidly reaching the conclusion that tightly coupled sensor processing loses too much potentially critical information.1 Hence upstream (raw and partially processed) data must be extracted, rapidly archived, and advertised to the enterprise for unanticipated uses. The authors believe layered sensing net-centric integration can be achieved through a standardize-encapsulate-syndicateaggregate- manipulate-process paradigm. The Sensor Layer Prototype's technical approach focuses on implementing this proof of concept framework to make sensor data visible, accessible and useful to the enterprise. To achieve this, a "raw" data tap between physical transducers associated with sensor arrays and the embedded sensor signal processing hardware and software has been exploited. Second, we encapsulate and expose both raw and partially processed data to the enterprise within the context of a service-oriented architecture. Third, we advertise the presence of multiple types, and multiple layers of data through geographic-enabled Really Simple Syndication (GeoRSS) services. These GeoRSS feeds are aggregated, manipulated, and filtered by a feed aggregator. After filtering these feeds to bring just the type

  13. Majorana Thermosyphon Prototype Experimental Setup

    Energy Technology Data Exchange (ETDEWEB)

    Reid, Douglas J.; Guzman, Anthony D.; Munley, John T.

    2011-08-01

    This report presents the experimental setup of Pacific Northwest National Laboratory’s MAJORANA DEMONSTRATOR thermosyphon prototype cooling system. A nitrogen thermosyphon prototype of such a system has been built and tested at PNNL. This document presents the experimental setup of the prototype that successfully demonstrated the heat transfer performance of the system.

  14. OPAL Jet Chamber Prototype

    CERN Multimedia

    OPAL was one of the four experiments installed at the LEP particle accelerator from 1989 - 2000. OPAL's central tracking system consists of (in order of increasing radius) a silicon microvertex detector, a vertex detector, a jet chamber, and z-chambers. All the tracking detectors work by observing the ionization of atoms by charged particles passing by: when the atoms are ionized, electrons are knocked out of their atomic orbitals, and are then able to move freely in the detector. These ionization electrons are detected in the dirfferent parts of the tracking system. This piece is a prototype of the jet chambers

  15. Prototyping Augmented Reality

    CERN Document Server

    Mullen, Tony

    2011-01-01

    Learn to create augmented reality apps using Processing open-source programming language Augmented reality (AR) is used all over, and you may not even realize it. Smartphones overlay data onto live camera views to show homes for sale, restaurants, or historical sites. American football broadcasts use AR to show the invisible first-down line on the field to TV viewers. Nike and Budweiser, among others, have used AR in ads. Now, you can learn to create AR prototypes using 3D data, Processing open-source programming language, and other languages. This unique book is an easy-to-follow guide on how

  16. Internet Banking System Prototype

    CERN Document Server

    Alnaqeib, Rami; Jalab, Hamid A; Zaidan, M A; Hmood, Ali K

    2010-01-01

    Internet Banking System refers to systems that enable bank customers to access accounts and general information on bank products and services through a personal computer or other intelligent device. Internet banking products and services can include detailed account information for corporate customers as well as account summery and transfer money. Ultimately, the products and services obtained through Internet Banking may mirror products and services offered through other bank delivery channels. In this paper, Internet Banking System Prototype has been proposed in order to illustrate the services which is provided by the Bank online services.

  17. Exchange-induced Tm magnetism in multiferroic h-TmMnO{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Salama, Hazar A; Stewart, G A [School of Physical, Environmental and Mathematical Sciences, University of New South Wales, Australian Defence Force Academy, Canberra 2600 (Australia)

    2009-09-23

    Analysis of {sup 169}Tm Moessbauer spectra recorded for (hexagonal phase) h- TmMnO{sub 3} confirms that the Mn sublattice orders magnetically below T{sub N}{sup Mn} = 82-83 K and reveals the growth of a local Tm moment at the 4b site that is induced by the Mn-Tm exchange interaction. The maximum hyperfine field recorded at the {sup 169}Tm nucleus is 312 T, which is just under half of the free ion value and corresponds to a saturation moment of 3.29 mu{sub B}. The temperature dependence of the fitted magnetic hyperfine interaction is closely represented by a simple two-singlet ground state model for the Tm{sup 3+} crystal field scheme. The saturation molecular field is deduced to lie in the range B{sub Mn-Tm}(T = 0 K) = 1.2-2.3 T, dependent on the expectation value of the coupling alpha = (0|J{sub z}|1) between the two-singlet states. As observed elsewhere for other hexagonal manganites, there is no Mn-based exchange field at the second Tm site (the 2a site) which contributes a paramagnetic subspectrum down to the lowest experimental temperature of 4.2 K.

  18. DataCollection Prototyping

    CERN Multimedia

    Beck, H.P.

    DataCollection is a subsystem of the Trigger, DAQ & DCS project responsible for the movement of event data from the ROS to the High Level Triggers. This includes data from Regions of Interest (RoIs) for Level 2, building complete events for the Event Filter and finally transferring accepted events to Mass Storage. It also handles passing the LVL1 RoI pointers and the allocation of Level 2 processors and load balancing of Event Building. During the last 18 months DataCollection has developed a common architecture for the hardware and software required. This involved a radical redesign integrating ideas from separate parts of earlier TDAQ work. An important milestone for this work, now achieved, has been to demonstrate this subsystem in the so-called Phase 2A Integrated Prototype. This prototype comprises the various TDAQ hardware and software components (ROSs, LVL2, etc.) under the control of the TDAQ Online software. The basic functionality has been demonstrated on small testbeds (~8-10 processing nodes)...

  19. Linearly polarized single TM mode terahertz waveguide.

    Science.gov (United States)

    Li, Haisu; Ren, Guobin; Atakaramians, Shaghik; Kuhlmey, Boris T; Jian, Shuisheng

    2016-09-01

    We design a hollow-core terahertz (THz) waveguide guiding a single linearly polarized mode. This is achieved using a hybrid cladding, where we introduce a ring of subwavelength structures, including metal wires and air-holes. The wire-based cladding is extremely anisotropic, reflecting only transverse magnetic (TM) modes. The polarization of TM modes is further manipulated by replacing some wires with air-holes. Numerical simulations confirm the guidance of only an x-polarized TM2 mode over 0.36-0.46 THz in a wavelength-scale core (diameter of 1 mm). The propagation losses are of the order 0.25  dB/cm, with low bend losses <0.3  dB/cm at 0.4 THz for a bend radius of 5 cm. PMID:27607958

  20. Prototyping Design and Business

    DEFF Research Database (Denmark)

    Rasmussen, Jørgen; Kramp, Gunnar; Schiønning Mortensen, Bo

    2011-01-01

    It is increasingly common that design firms go from working with their client’s development department on specific products, to discussing strategic issues directly with the company’s management. In this new territory designers face a number of challenges. Designers are traditionally trained...... to ‘look into the future,’ to find unidentified opportunities through an open process and to validate their decisions through repeated prototyping. Management, on the other hand, is traditionally trained to ‘look into to the past’ and make decisions based on thoroughly analyzing existing information....... This paper suggests a model, ‘The Strategic Design Matrix,’ to bridge the gap between the design approach and the management approach to strategic development processes. Through common references, a common language and a common basis understanding, the model aims to create a communicative platform...

  1. EEM{sup TM} wireless supervision

    Energy Technology Data Exchange (ETDEWEB)

    Bilic, H. [Ericsson-Nikola Tesla d.d. Zagreb (Croatia)

    2000-07-01

    By adding the GSM network to the communication level of Energy Management systems, energy operating centres (EOC) can offer wireless access to the supervised equipment. Furthermore EOC can profit from rapid service development in the GSM networks. With implementation of GPRS to the GSM network EOC can instantly offer wireless access to external IP based networks such as Internet and corporate Intranets. The author describes architecture and key characteristic of Ericsson EnergyMaster{sup TM} (EEM{sup TM}) system for Energy Management, how and where to implement wireless supervision, wireless access to IP addresses and also how to implement new services provided by the GSM network. (orig.)

  2. Prototypes as Platforms for Participation

    DEFF Research Database (Denmark)

    Horst, Willem

    that invite the participation of different stakeholders based on my involvement in the development process of an interactive product in industry. I demonstrate that involving non-designers in the making and shaping of the prototype enables them to take active part in the reflective learning process......The development of interactive products in industry is an activity involving different disciplines – such as different kinds of designers, engineers, marketers and managers – in which prototypes play an important role. On the one hand, prototypes can be powerful boundary objects and an effective...... of prototyping, and develop a sense of ownership over the prototype. This has several benefits for the interaction designer. Since participants learn about the design space and limitations of the prototype, they are able to give specific feedback and input, which the interaction designer can implement. Moreover...

  3. Electrochemical reduction of Tm on Mg electrodes and co-reduction of Mg, Li and Tm on W electrodes

    International Nuclear Information System (INIS)

    The reduction process of Tm(III) ions was investigated in LiCl–KCl–MgCl2 melt on a W electrode and in LiCl–KCl melt on a Mg electrode at 753 K, respectively. On the W electrode, in LiCl–KCl–MgCl2 melt the reduction of Tm(III) ions was a two-step process: Tm(III) + e−1 → Tm(II) and yTm(II) + 2ye−1 + xMg → MgxTmy. The reduction process of Tm(III)/Tm(II) was not observed on the Mg electrode, and only two signals, related to Mg–Tm intermetallic compounds were observed, in the cyclic voltammogram and chronopotentiogram. Galvanostatic electrolysis was employed to prepare Mg–Li–Tm alloys on both W and Mg electrodes. The deposits were characterized by X-ray diffraction (XRD), optical microscopy (OM) and scanning electron microscopy (SEM). Mg24Tm5 and Mg2Tm phases were detected in the deposits. The effect of Tm addition on Mg–Li alloy was investigated via potentiodynamic polarization and OM at room temperature. The grain size of Mg–Li alloy becomes much smaller after addition of Tm element. The corrosion potentials of Mg–Li–Tm alloys shift toward a more positive direction than that of Mg–Li alloy

  4. Mobile prototyping with Axure 7

    CERN Document Server

    Hacker, Will

    2013-01-01

    This book is a step-by-step tutorial which includes hands-on examples and downloadable Axure files to get you started with mobile prototyping immediately. You will learn how to develop an application from scratch, and will be guided through each and every step.If you are a mobile-centric developer/designer, or someone who would like to take their Axure prototyping skills to the next level and start designing and testing mobile prototypes, this book is ideal for you. You should be familiar with prototyping and Axure specifically, before you read this book.

  5. Defying Gravity Using Jenga[TM] Blocks

    Science.gov (United States)

    Tan, Yin-Soo; Yap, Kueh-Chin

    2007-01-01

    This paper describes how Jenga[TM] blocks can be used to demonstrate the physics of an overhanging tower that appears to defy gravity. We also propose ideas for how this demonstration can be adapted for the A-level physics curriculum. (Contains 8 figures and 1 table.)

  6. 78 FR 72922 - TSA Pre✓TM

    Science.gov (United States)

    2013-12-04

    ... Pre TM Application Program, including the cost of conducting the security threat assessment and... covers TSA's costs for conducting the security threat assessment and adjudicating the application; and (3... aggregate costs associated with the program and shall be credited to the Transportation...

  7. The Neuroscience of PowerPoint[TM

    Science.gov (United States)

    Horvath, Jared Cooney

    2014-01-01

    Many concepts have been published relevant to improving the design of PowerPoint[TM] (PP) presentations for didactic purposes, including the redundancy, modality, and signaling principles of multimedia learning. In this article, we review the recent neuroimaging findings that have emerged elucidating the neural structures involved in many of these…

  8. Quench performance and mechanical behavior of the first Fermilab- built prototype high gradient quadrupole for the LHC interaction regions

    CERN Document Server

    Andreev, N; Bauer, P; Bossert, R; Brandt, J; Carson, J; Caspi, S; Chichili, D R; Di Marco, J; Fehér, S; Ghosh, A; Glass, H; Kerby, J S; Lamm, M J; Makarov, A; McInturff, A D; Nicol, T H; Nobrega, A; Novitski, I; Orris, D; Peterson, T; Rabehl, Roger Jon; Robotham, W; Scanlan, R M; Schlabach, P; Sylvester, C D; Strait, J B; Tartaglia, A; Tompkins, J C; Velev, G V; Yadav, S; Zlobin, A V

    2002-01-01

    As part of the US LHC program to provide high gradient superconducting quadrupoles for the LHC interaction regions, a 5.5 meter long prototype magnet has been built and tested horizontally in a production type cryostat at Fermilab. This prototype magnet was used to validate the mechanical and magnetic design, production fabrication and assembly tooling. The first prototype magnet has met the LHC requirements of operating at 215 T/m with excellent magnetic field harmonics. This paper summarizes the test results of this magnet, including quench tests and mechanical behavior over several thermal cycles. (11 refs).

  9. UA1 prototype detector

    CERN Multimedia

    1980-01-01

    Prototype of UA1 central detector inside a plexi tube. The UA1 central detector was crucial to understanding the complex topology of proton-antiproton events. It played a most important role in identifying a handful of Ws and Zs among billions of collisions. The detector was a 6-chamber cylindrical assembly 5.8 m long and 2.3 m in diameter, the largest imaging drift chamber of its day. It recorded the tracks of charged particles curving in a 0.7 Tesla magnetic field, measuring their momentum, the sign of their electric charge and their rate of energy loss (dE/dx). Atoms in the argon-ethane gas mixture filling the chambers were ionised by the passage of charged particles. The electrons which were released drifted along an electric field shaped by field wires and were collected on sense wires. The geometrical arrangement of the 17000 field wires and 6125 sense wires allowed a spectacular 3-D interactive display of reconstructed physics events to be produced.

  10. Window prototypes during the project

    DEFF Research Database (Denmark)

    Schultz, Jørgen Munthe

    1996-01-01

    The conditions for the PASSYS test and the results of the measurements on one of the aerogel window prototypes are described.......The conditions for the PASSYS test and the results of the measurements on one of the aerogel window prototypes are described....

  11. Radiative lifetime measurements of some Tm I and Tm II levels by time-resolved laser spectroscopy

    Science.gov (United States)

    Tian, Yanshan; Wang, Xinghao; Yu, Qi; Li, Yongfan; Gao, Yang; Dai, Zhenwen

    2016-04-01

    Radiative lifetimes of 88 levels of Tm I in the energy range 22 791.176-48 547.98 cm-1 and 29 levels of Tm II in the range 27 294.79-65 612.85 cm-1 were measured by time-resolved laser-induced fluorescence spectroscopy in laser-ablation plasma. The lifetime values obtained are in the range from 15.4 to 7900 ns for Tm I and from 36.5 to 1000 ns for Tm II. To the best of our knowledge, 77 lifetimes of Tm I and 22 lifetimes of Tm II are reported for the first time. Good agreements between the present results and the previous experimental values were achieved for both Tm I and Tm II.

  12. Reliability and Validity of the Zephyr[TM] BioHarness[TM] to Measure Respiratory Responses to Exercise

    Science.gov (United States)

    Hailstone, Jono; Kilding, Andrew E.

    2011-01-01

    The Zephyr[TM] BioHarness[TM] (Zephyr Technology, Auckland, New Zealand) is a wireless physiological monitoring system that has the ability to measure respiratory rate unobtrusively. However, the ability of the BioHarness[TM] to accurately and reproducibly determine respiratory rate across a range of intensities is currently unknown. The aim of…

  13. PRIze{sup TM} 1.2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    PRIze{sup TM} 1.2 is a computer program that evaluates the improved oil recovery (IOR) potential of petroleum reservoirs including the use of horizontal wells. It was created in 1992 and has since been used in over 800 reservoir evaluations. The tool provides information on the feasibility of IOR processes based on reservoir parameters. PRIze{sup TM} makes predictions for chemical, gas injection and thermal IOR processes based on both vertical and horizontal wells. The program provides a uniform data entry screen that allows the user to input 42 average values of geological parameters, fluid properties and oil production mechanism information into a data file. The data can be used to provide a production forecast, and enable the user to establish, to a first order approximation, the economic viability of a given process.

  14. Cryogenic Tm:YAP microchip laser

    Science.gov (United States)

    Hubka, Zbyněk.; Å ulc, Jan; Jelínková, Helena; Nejezchleb, Karel; Å koda, Václav

    2016-04-01

    The spectral characteristics of laser active media, and thus those of the laser output, are temperature dependent. Specifically, in almost every crystal host, cooling to low temperatures leads to better heat removal, a higher efficiency and output power, and a reduced lasing threshold. Tm-ion doped lasers have an emission wavelength around 2 μm and are important in medicine for soft tissue cutting and hemostasis, as well as in LIDAR or atmosphere sensing technology. This paper presents the performance-temperature dependency of a 4 at. % doped Tm:YAP microchip. During the experiment the Tm:YAP crystal was placed inside an evacuated liquid nitrogen cryostat on a cooling finger. As its temperature was varied from 80 K to 340 K, changes were observed in the absorption spectrum, ranging from 750 nm to 2000 nm and in the fluorescence spectrum from 1600 nm to 2050 nm. Fluorescence lifetime was seen to rise and fall with decreasing temperature. The laser was pumped by a 792 nm laser diode and at 80 K the maximum output peak power of the laser was 4.6 W with 23 % slope efficiency and 0.6 W threshold, compared to 2.4 W output peak power, 13 % slope efficiency and 3.3 W threshold when at 340 K. The laser emission wavelength changed from 1883 nm to 1993 nm for 80 K and 300 K, respectively.

  15. Learning Axure RP interactive prototypes

    CERN Document Server

    Krahenbuhl, John Henry

    2015-01-01

    If you are a user experience professional, designer, information architect, or business analyst who wants to gain interactive prototyping skills with Axure, then this book is ideal for you. Some familiarity with Axure is preferred but not essential.

  16. Architectural Prototyping in Industrial Practice

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2008-01-01

    Architectural prototyping is the process of using executable code to investigate stakeholders’ software architecture concerns with respect to a system under development. Previous work has established this as a useful and cost-effective way of exploration and learning of the design space of a system......, in addressing issues regarding quality attributes, in addressing architectural risks, and in addressing the problem of knowledge transfer and conformance. Little work has been reported so far on the actual industrial use of architectural prototyping. In this paper, we report from an ethnographical study...... prototypes include end-user or business related functionality rather than purely architectural functionality. Based on these observations we provide recommendations for effective industrial architectural prototyping....

  17. Role model and prototype matching

    DEFF Research Database (Denmark)

    Lykkegaard, Eva; Ulriksen, Lars

    2016-01-01

    Previous research has found that young people’s prototypes of science students and scientists affect their inclination to choose tertiary STEM programs (Science, Technology, Engineering and Mathematics). Consequently, many recruitment initiatives include role models to challenge these prototypes....... The present study followed 15 STEM-oriented upper-secondary school students from university-distant backgrounds during and after their participation in an 18-months long university-based recruitment and outreach project involving tertiary STEM students as role models. The analysis focusses on how the students......’ meetings with the role models affected their thoughts concerning STEM students and attending university. The regular self-to-prototype matching process was shown in real-life role-models meetings to be extended to a more complex three-way matching process between students’ self-perceptions, prototype...

  18. Prototype design for autonomous vehicle

    OpenAIRE

    Lehander, Jacob; Persson, Joel

    2015-01-01

    This thesis describes the mechanical design of a prototype vehicle developed for a company located in California. The project was based on an earlier vehicle located at KTH, Transport Labs, and investigated if the existing concept for the vehicle would work as a concept for an autonomous prototype, with focus on component layout and increased forces. The design of the vehicle is based on a concept with a carbon fiber bottom plate, two separate suspension modules with electric hub motors and s...

  19. Economical Investigation of Rapid Prototyping

    OpenAIRE

    Péter Ficzere; Lajos Borbás; Ádám Török

    2013-01-01

    Usage of rapid prototyping gain developers, designers and engineers more time and consume less money and save more resources. In this article authors investigated the economic possibilities of rapid prototyping. In concurrent engineering, different tasks are tackled at the same time, and not necessarily in the usual order. Concurrent engineering is a method by which several teams within an organization work simultaneously to develop new products and allows more flexible approach. The concurre...

  20. A Quantum Monte Carlo Study of mono(benzene)TM and bis(benzene)TM Systems

    CERN Document Server

    Bennett, M Chandler; Mitas, Lubos

    2016-01-01

    We present a study of mono(benzene)TM and bis(benzene)TM systems, where TM={Mo,W}. We calculate the binding energies by quantum Monte Carlo (QMC) approaches and compare the results with other methods and available experiments. The orbitals for the determinantal part of each trial wave function were generated from several types of DFT in order to optimize for fixed-node errors. We estimate and compare the size of the fixed-node errors for both the Mo and W systems with regard to the electron density and degree of localization in these systems. For the W systems we provide benchmarking results of the binding energies, given that experimental data is not available.

  1. Laser brackets debonding: Tm:YAP and ClarityTM SL self-ligating appliance system

    Science.gov (United States)

    Dostálová, Tatjana; Jelínková, Helena; Šulc, Jan; Koranda, Petr; Němec, Michal; Jelínek, Michal; Fibrich, Martin; Michalik, Pavel; Miyagi, Mitsunobu

    2010-02-01

    The study demonstrates the possibility of using Tm:YAP laser radiation for the removing ceramic brackets. The amount of enamel loss and residual resin on teeth has been evaluated. A diode-pumped Tm:YAP microchip laser generating at wavelength 1.9 μm was used for the debonding process. The transmission and absorption measurement of the basic elements - bracket, adhesive resin, and enamel was analyzed to explain the source of the heat and bracket debonding. Quantitative measurements are made for visualizing enamel surface before and after a self-ligating bonding technique. Temperature rise observation during the debonding procedure - from 0.5 to 2 W power - has improved the accuracy of assessment. The results were evaluated by CCD camera and scanning electron microscope. From the measurements it is possible to conclude that continuously running small diode pumped Tm:YAP microchip laser having output power 1W can remove the ceramic bracket without enamel iatrogenic damage.

  2. Intensification of the Learning Process: Prototype Curriculum Guides.

    Science.gov (United States)

    Bucks County Public Schools, Doylestown, PA.

    A general rationale and a specific blueprint for developing curriculum are presented. (See TM 001 363 for description of total project; for other related documents, see TM 001 160, TM 001 364-373.) (MS)

  3. Cryogenic tests of the first two LHC quadrupole prototypes

    Energy Technology Data Exchange (ETDEWEB)

    Genevey, P.; Deregel, J.; Perot, J.; Rifflet, J.M.; Vedrine, P.; Cortella, J.; Le Coroller, A. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Dept. d`Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l`Instrumentation Associee; Rodriguez-Mateos, F.; Siegel, N.; Tortschanoff, T.; Verweij, A.P. [European Organization for Nuclear Research, Geneva (Switzerland)

    1994-12-31

    Two LHC (Large Hadron Collider) twin aperture quadrupole prototypes were constructed at CEA Saclay (a CERN-CEA collaboration agreement). Their main characteristics are: 3.05 m length, 56 mm coil aperture, 180 mm between the two apertures, 252 T/m nominal gradient at 15060 A. They have been tested and measured in the 1.8 K Saclay test facility in an horizontal cryostat. The magnets are instrumented in order to investigate their behaviour during cool-down, stand-by, powering and current ramping, quenching and warming-up. A summary of the cryogenic, mechanical, pressure and electrical measurements is presented. The quench protection heaters are efficient down to 3000 A. Losses during ramping up and down are reported. (from authors) 5 fig., 11 ref.

  4. ACR-1000TM - advanced Candu reactor design

    International Nuclear Information System (INIS)

    Atomic Energy of Canada Limited (AECL) has developed the Advanced CANDU ReactorTM- 1000 (ACR-1000TM) as an evolutionary advancement of the current CANDU 6TM reactor. This evolutionary advancement is based on AECL's in-depth knowledge of CANDU structures, systems, components and materials, gained during 50 years of continuous construction, engineering and commissioning, as well as on the experience and feedback received from operators of CANDU plants. The ACR design retains the proven strengths and features of CANDU reactors, while incorporating innovations and state-of-the-art technology. These innovations improve economics, inherent safety characteristics, and performance, while retaining the proven benefits of the CANDU family of nuclear power plants. The Canadian nuclear reactor design evolution that has reached today's stage represented by the ACR-1000, has a long history dating back to the early 1950's. In this regard, Canada is in a unique situation, shared only by a very few other countries, where original nuclear power technology has been invented and further developed. The ACR design has been reviewed by domestic and international regulatory bodies, and has been given a positive regulatory opinion about its licensability. The Canadian regulator, the Canadian Nuclear Safety Commission (CNSC) completed the Phase 1 and Phase 2 pre-project design reviews in December 2008 and August 2009, respectively, and concluded that there are no fundamental barriers to licensing the ACR-1000 design in Canada. The final stage of the ACR-1000 design is currently underway and will be completed by fall of 2011, along with the final elements of the safety analyses and probabilistic safety analyses supporting the finalized design. The generic Preliminary Safety Analysis Report (PSAR) for the ACR-1000 was completed in September 2009. The PSAR demonstrates ACR-1000 safety case and compliance with Canadian and international regulatory requirements and expectations. (authors)

  5. Drinker prototypes in American society.

    Science.gov (United States)

    Klein, H; Pittman, D J

    1990-01-01

    Based on a national probability sample of 2,401 Americans age 21 and over (1,069 of whom were deemed "drinkers" on the basis of having consumed at least one alcoholic beverage in the past 7 days), this study develops profiles of the drinker and heavier drinking prototypes for beer, distilled spirits, wine, and wine cooler drinkers. Both beer-drinking prototypes are mainly composed of less well-educated males who drink beer in circumstances unconnected with any mealtime setting. Wine drinkers are more often women (although the heavy drinking prototype is more likely to be a man), usually with education at or beyond the "some college" level, who typically drink wine in moderation with a meal such as dinner. Both prototypes of the distilled spirits drinkers are likely to be men, age 45 or over, who are not currently married, who usually drink in a bar, before a meal, when they feel somewhat happy or calm. Wine cooler drinkers are much more heterogeneous, and hence less distinguishable than the other drinking prototypes. The heavier wine cooler drinker, however, is likely to be single, with 12 or 13 years of schooling. This person usually drinks when feeling very stimulated, very happy, very romantic, or else very bored, and often does so at bars or in friends' homes.

  6. Neutron capture measurements on {sup 171}Tm

    Energy Technology Data Exchange (ETDEWEB)

    Reifarth, R. E-mail: www.reifarth@lanl.gov; Haight, R.; Heil, M.; Fowler, M.M.; Kaeppeler, F.; Miller, G.G.; Rundberg, R.S.; Ullmann, J.L.; Wilhelmy, J.B

    2003-05-05

    A first proof of principal experiment of measuring neutron capture cross sections of radioactive isotopes was performed on {sup 171}Tm which has a half life of 1.92 years. This isotope was chosen for its ease of production and its radiation properties. The experiment was done at an 8 meter irradiation station at LANSCE using the pulse height weighting technique. A complemental activation measurement at FZK as well as a theoretical estimation indicated a significant background component above 1 keV neutron energy during the experiment at LANSCE.

  7. Electrochemical formation of Al–Tm intermetallics in eutectic LiCl–KCl melt containing Tm and Al ions

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xing [Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin 150001 (China); Yan, Yong-De, E-mail: y5d2006@hrbeu.edu.cn [Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin 150001 (China); Fundamental Science on Nuclear Safety and Simulation Technology Laboratory, Harbin Engineering University, Harbin 150001 (China); Zhang, Mi-Lin; Tang, Hao; Ji, De-Bin; Han, Wei [Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin 150001 (China); Xue, Yun; Zhang, Zhi-Jian [Fundamental Science on Nuclear Safety and Simulation Technology Laboratory, Harbin Engineering University, Harbin 150001 (China)

    2014-09-15

    This work focuses on investigating the electrochemical formation of Al–Tm and Al–Li–Tm alloys in LiCl–KCl–AlCl{sub 3}–Tm{sub 2}O{sub 3} melt on both W and Al electrodes. Thermodynamic calculation and electrochemical behavior of LiCl–KCl melt containing both AlCl{sub 3} and Tm{sub 2}O{sub 3} showed that AlCl{sub 3} can chlorinate Tm{sub 2}O{sub 3} to release Tm(III) ions. Three kinds of Al–Tm intermetallics at about −1.26, −1.32 and −1.43 V were detected by means of various electrochemical measurement techniques, i.e. cyclic voltammetry, square wave voltammetry and open circuit chronopotentiometry. Potentiostatic and galvanostatic electrolysis were carried out on Al and W electrodes to prepare Al–Tm and Al–Li–Tm alloys, respectively. The composition of Al–Li–Tm alloys was analyzed by inductive coupled plasma atomic emission spectrometer (ICP-AES)

  8. Family C 7TM receptor dimerization and activation

    DEFF Research Database (Denmark)

    Bonde, Marie Mi; Sheikh, Søren P; Hansen, Jakob Lerche

    2006-01-01

    The family C seven transmembrane (7TM) receptors constitutes a small and especially well characterized subfamily of the large 7TM receptor superfamily. Approximately 50% of current prescription drugs target 7TM receptors, this biologically important family represents the largest class of drug......-targets today. It is well established that family C 7TM receptors form homo- or hetero-dimers on the cell surface of living cells. The large extra-cellular domains (ECD) have been crystallized as a dimer in the presence and absence of agonist. Upon agonist binding, the dimeric ECD undergoes large conformational...... to be fully defined. This review presents the biochemical support for family C 7TM receptor dimerization and discusses its importance for receptor biosynthesis, surface expression, ligand binding and activation, since lessons learnt here may well be applicable to the whole superfamily of 7TM receptors....

  9. Science with the ASTRI prototype

    CERN Document Server

    ,

    2013-01-01

    ASTRI (Astrofisica a Specchi con Tecnologia Replicante Italiana) is a "Flagship Project" financed by the Italian Ministry of Instruction, University and Research and led by the Italian National Institute of Astrophysics. It represents the Italian proposal for the development of the Small Size Telescope system of the Cherenkov Telescope Array, the next generation observatory for Very High Energy gamma-rays (20 GeV - 100 TeV). The ASTRI end-to-end prototype will be installed at Serra La Nave (Catania, Italy) and it will see the first light at the beginning of 2014. We describe the expected performance of the prototype on few selected test cases of the northern emisphere. The aim of the prototype is to probe the technological solutions and the nominal performance of the various telescope's subsystems.

  10. Towards an Operational Framework for Architectural Prototyping

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak

    2005-01-01

    We use a case study in architectural prototyping as input for presenting a first, tentative, framework describing key concepts and their relationships in architectural prototyping processes.......We use a case study in architectural prototyping as input for presenting a first, tentative, framework describing key concepts and their relationships in architectural prototyping processes....

  11. Graphing Calculators, the CBL2[TM] and TI-Interactive[TM] in High School Science.

    Science.gov (United States)

    Molnar, Bill

    This collection of activities is designed to show how TI-Interactive[TM] and Calculator-based Laboratories (CBL) can be used to explore topics in high school science. The activities address such topics as specific heat, Boyle's Law, Newton's Law of Cooling, and Antarctic Ozone Levels. Teaching notes and calculator instructions are included as are…

  12. End-Pumped Tm:YAG Ceramic Slab Lasers

    Institute of Scientific and Technical Information of China (English)

    CHENG Xiao-Jin; XU Jian-Qiu; ZHANG Wen-Xin; JIANG Sen-Xue; PAN Yu-Bai

    2009-01-01

    Lasers from a Tm:YAG ceramic aare reported for the first time to our best knowledge. The Tm:YAG ceramic slab is end-pumped by a laser diode with central wavelength 792nm. At room temperature, the maximum continuous-wave output power is 4.5 W, and the sloping efficiency is obtained to be 20.5%. The laser spectrum of the Tm: YAG ceramic is centered at 2015 nm.

  13. Structural and functional importance of transmembrane domain 3 (TM3) in the aspartate:alanine antiporter AspT: topology and function of the residues of TM3 and oligomerization of AspT.

    Science.gov (United States)

    Nanatani, Kei; Maloney, Peter C; Abe, Keietsu

    2009-04-01

    AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, a membrane protein of 543 amino acids with 10 putative transmembrane (TM) helices, is the prototype of the aspartate:alanine exchanger (AAE) family of transporters. Because TM3 (isoleucine 64 to methionine 85) has many amino acid residues that are conserved among members of the AAE family and because TM3 contains two charged residues and four polar residues, it is thought to be located near (or to form part of) the substrate translocation pathway that includes the binding site for the substrates. To elucidate the role of TM3 in the transport process, we carried out cysteine-scanning mutagenesis. The substitutions of tyrosine 75 and serine 84 had the strongest inhibitory effects on transport (initial rates of l-aspartate transport were below 15% of the rate for cysteine-less AspT). Considerable but less-marked effects were observed upon the replacement of methionine 70, phenylalanine 71, glycine 74, arginine 76, serine 83, and methionine 85 (initial rates between 15% and 30% of the rate for cysteine-less AspT). Introduced cysteine residues at the cytoplasmic half of TM3 could be labeled with Oregon green maleimide (OGM), whereas cysteines close to the periplasmic half (residues 64 to 75) were not labeled. These results suggest that TM3 has a hydrophobic core on the periplasmic half and that hydrophilic residues on the cytoplasmic half of TM3 participate in the formation of an aqueous cavity in membranes. Furthermore, the presence of l-aspartate protected the cysteine introduced at glycine 62 against a reaction with OGM. In contrast, l-aspartate stimulated the reactivity of the cysteine introduced at proline 79 with OGM. These results demonstrate that TM3 undergoes l-aspartate-induced conformational alterations. In addition, nonreducing sodium dodecyl sulfate-polyacrylamide gel electrophoresis analyses and a glutaraldehyde cross-linking assay suggest that functional AspT forms homo-oligomers as a

  14. Structural and Functional Importance of Transmembrane Domain 3 (TM3) in the Aspartate:Alanine Antiporter AspT: Topology and Function of the Residues of TM3 and Oligomerization of AspT▿

    Science.gov (United States)

    Nanatani, Kei; Maloney, Peter C.; Abe, Keietsu

    2009-01-01

    AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, a membrane protein of 543 amino acids with 10 putative transmembrane (TM) helices, is the prototype of the aspartate:alanine exchanger (AAE) family of transporters. Because TM3 (isoleucine 64 to methionine 85) has many amino acid residues that are conserved among members of the AAE family and because TM3 contains two charged residues and four polar residues, it is thought to be located near (or to form part of) the substrate translocation pathway that includes the binding site for the substrates. To elucidate the role of TM3 in the transport process, we carried out cysteine-scanning mutagenesis. The substitutions of tyrosine 75 and serine 84 had the strongest inhibitory effects on transport (initial rates of l-aspartate transport were below 15% of the rate for cysteine-less AspT). Considerable but less-marked effects were observed upon the replacement of methionine 70, phenylalanine 71, glycine 74, arginine 76, serine 83, and methionine 85 (initial rates between 15% and 30% of the rate for cysteine-less AspT). Introduced cysteine residues at the cytoplasmic half of TM3 could be labeled with Oregon green maleimide (OGM), whereas cysteines close to the periplasmic half (residues 64 to 75) were not labeled. These results suggest that TM3 has a hydrophobic core on the periplasmic half and that hydrophilic residues on the cytoplasmic half of TM3 participate in the formation of an aqueous cavity in membranes. Furthermore, the presence of l-aspartate protected the cysteine introduced at glycine 62 against a reaction with OGM. In contrast, l-aspartate stimulated the reactivity of the cysteine introduced at proline 79 with OGM. These results demonstrate that TM3 undergoes l-aspartate-induced conformational alterations. In addition, nonreducing sodium dodecyl sulfate-polyacrylamide gel electrophoresis analyses and a glutaraldehyde cross-linking assay suggest that functional AspT forms homo-oligomers as a

  15. Structural and functional importance of transmembrane domain 3 (TM3) in the aspartate:alanine antiporter AspT: topology and function of the residues of TM3 and oligomerization of AspT.

    Science.gov (United States)

    Nanatani, Kei; Maloney, Peter C; Abe, Keietsu

    2009-04-01

    AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, a membrane protein of 543 amino acids with 10 putative transmembrane (TM) helices, is the prototype of the aspartate:alanine exchanger (AAE) family of transporters. Because TM3 (isoleucine 64 to methionine 85) has many amino acid residues that are conserved among members of the AAE family and because TM3 contains two charged residues and four polar residues, it is thought to be located near (or to form part of) the substrate translocation pathway that includes the binding site for the substrates. To elucidate the role of TM3 in the transport process, we carried out cysteine-scanning mutagenesis. The substitutions of tyrosine 75 and serine 84 had the strongest inhibitory effects on transport (initial rates of l-aspartate transport were below 15% of the rate for cysteine-less AspT). Considerable but less-marked effects were observed upon the replacement of methionine 70, phenylalanine 71, glycine 74, arginine 76, serine 83, and methionine 85 (initial rates between 15% and 30% of the rate for cysteine-less AspT). Introduced cysteine residues at the cytoplasmic half of TM3 could be labeled with Oregon green maleimide (OGM), whereas cysteines close to the periplasmic half (residues 64 to 75) were not labeled. These results suggest that TM3 has a hydrophobic core on the periplasmic half and that hydrophilic residues on the cytoplasmic half of TM3 participate in the formation of an aqueous cavity in membranes. Furthermore, the presence of l-aspartate protected the cysteine introduced at glycine 62 against a reaction with OGM. In contrast, l-aspartate stimulated the reactivity of the cysteine introduced at proline 79 with OGM. These results demonstrate that TM3 undergoes l-aspartate-induced conformational alterations. In addition, nonreducing sodium dodecyl sulfate-polyacrylamide gel electrophoresis analyses and a glutaraldehyde cross-linking assay suggest that functional AspT forms homo-oligomers as a

  16. Digital Prototyping of Milk Products

    DEFF Research Database (Denmark)

    Frisvad, Jeppe Revall; Nielsen, Otto Højager Attermann; Skytte, Jacob Lercke;

    2012-01-01

    Digital prototyping has revolutionised the automotive industry by providing designers and engineers with digital models of their products that enable virtual product design, visualisation, and simulation [1]. However, digital prototyping does not exist in the food industry as the colloidal nature...... is by static light scattering measurements. This, however, is an invasive procedure where a sample must be placed in a relatively small container (like a cuvette) and scanned by a photon detector orbiting the sample. The container must be small enough to ensure that the sample enters the single scattering...

  17. Axure RP 6 Prototyping Essentials

    CERN Document Server

    Schwartz, Ezra

    2012-01-01

    Axure RP 6 Prototyping Essentials is a detailed, practical primer on the leading rapid prototyping tool. Short on jargon and high on concepts, real-life scenarios and step-by-step guidance through hands-on examples, this book will show you how to integrate Axure into your UX workflow. This book is written for UX practitioners, business analysts, product managers, and anyone else who is involved in UX projects. The book assumes that you have no or very little familiarity with Axure. It will help you if you are evaluating the tool for an upcoming project or are required to quickly get up to spee

  18. Establishment and analysis of global gridded Tm Ts relationship model

    Institute of Scientific and Technical Information of China (English)

    Zeying Lan; Bao Zhang; Yichao Geng

    2016-01-01

    In ground-based GPS meteorology, Tm is a key parameter to calculate the conversion factor that can convert the zenith wet delay (ZWD) to precipitable water vapor (PWV). It is generally acknowledged that Tm is in an approximate linear relationship with surface temperature Ts, and the relationship presents regional variation. This paper employed sliding average method to calculate correlation coefficients and linear regression co-efficients between Tm and Ts at every 2? ? 2.5? grid point using Ts data from European Centre for Medium-Range Weather Forecasts (ECMWF) and Tm data from “GGOS Atmo-sphere”, yielding the grid and bilinear interpolation-based TmGrid model. Tested by Tm and Ts grid data, Constellation Observation System of Meteorology, Ionosphere, and Climate (COSMIC) data and radiosonde data, the TmGrid model shows a higher accuracy relative to the Bevis Tm ? Ts relationship which is widely used nowadays. The TmGrid model will be of certain practical value in high-precision PWV calculation.

  19. Rigidized Inflatable Veritex(TM) Structured For RF Antennas Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group inc. (CRG) proposes to demonstrate the feasibility of a lightweight, deployable Veritex TM supporting annulus structure to support large...

  20. Rapid prototyping and stereolithography in dentistry

    OpenAIRE

    Sanjna Nayar; Bhuminathan, S.; Wasim Manzoor Bhat

    2015-01-01

    The word rapid prototyping (RP) was first used in mechanical engineering field in the early 1980s to describe the act of producing a prototype, a unique product, the first product, or a reference model. In the past, prototypes were handmade by sculpting or casting, and their fabrication demanded a long time. Any and every prototype should undergo evaluation, correction of defects, and approval before the beginning of its mass or large scale production. Prototypes may also be used for specific...

  1. Encapsulation of polymer photovoltaic prototypes

    DEFF Research Database (Denmark)

    Krebs, Frederik C

    2006-01-01

    A simple and efficient method for the encapsulation of polymer and organic photovoltaic prototypes is presented. The method employs device preparation on glass substrates with subsequent sealing using glass fiber reinforced thermosetting epoxy (prepreg) against a back plate. The method allows...

  2. EUSO-TA prototype telescope

    Science.gov (United States)

    Bisconti, Francesca

    2016-07-01

    EUSO-TA is one of the prototypes developed for the JEM-EUSO project, a space-based large field-of-view telescope to observe the fluorescence light emitted by cosmic ray air showers in the atmosphere. EUSO-TA is a ground-based prototype located at the Telescope Array (TA) site in Utah, USA, where an Electron Light Source and a Central Laser Facility are installed. The purpose of the EUSO-TA project is to calibrate the prototype with the TA fluorescence detector in presence of well-known light sources and cosmic ray air showers. In 2015, the detector started the first measurements and tests using the mentioned light sources have been performed successfully. A first cosmic ray candidate has been observed, as well as stars of different magnitude and color index. Since Silicon Photo-Multipliers (SiPMs) are very promising for fluorescence telescopes of next generation, they are under consideration for the realization of a new prototype of EUSO Photo Detector Module (PDM). The response of this sensor type is under investigation through simulations and laboratory experimentation.

  3. A Reconsideration of Prototype Theory

    Institute of Scientific and Technical Information of China (English)

    马立文

    2008-01-01

    This paper makes an attempt to review the background when prototype theory was proposed,affirm its significant role in the study of psychology and linguistics and point out its theoretical deficiencies,which is helpful to reduce the Vacuous nature of the theory.

  4. Expo 86: An Escalation Prototype.

    Science.gov (United States)

    Ross, Jerry; Staw, Barry M.

    1986-01-01

    British Columbia remained committed to its decision to host a world's fair (Expo 86) despite rapidly increasing deficit projections. Expo is examined as a prototypical example of the escalation of commitment. Theory is proposed that integrates determinants of escalation from several levels of analysis over time. (CJH)

  5. Rapid Prototyping Enters Mainstream Manufacturing.

    Science.gov (United States)

    Winek, Gary

    1996-01-01

    Explains rapid prototyping, a process that uses computer-assisted design files to create a three-dimensional object automatically, speeding the industrial design process. Five commercially available systems and two emerging types--the 3-D printing process and repetitive masking and depositing--are described. (SK)

  6. Comparative 3-D Modeling of tmRNA

    Directory of Open Access Journals (Sweden)

    Wower Iwona

    2005-06-01

    Full Text Available Abstract Background Trans-translation releases stalled ribosomes from truncated mRNAs and tags defective proteins for proteolytic degradation using transfer-messenger RNA (tmRNA. This small stable RNA represents a hybrid of tRNA- and mRNA-like domains connected by a variable number of pseudoknots. Comparative sequence analysis of tmRNAs found in bacteria, plastids, and mitochondria provides considerable insights into their secondary structures. Progress toward understanding the molecular mechanism of template switching, which constitutes an essential step in trans-translation, is hampered by our limited knowledge about the three-dimensional folding of tmRNA. Results To facilitate experimental testing of the molecular intricacies of trans-translation, which often require appropriately modified tmRNA derivatives, we developed a procedure for building three-dimensional models of tmRNA. Using comparative sequence analysis, phylogenetically-supported 2-D structures were obtained to serve as input for the program ERNA-3D. Motifs containing loops and turns were extracted from the known structures of other RNAs and used to improve the tmRNA models. Biologically feasible 3-D models for the entire tmRNA molecule could be obtained. The models were characterized by a functionally significant close proximity between the tRNA-like domain and the resume codon. Potential conformational changes which might lead to a more open structure of tmRNA upon binding to the ribosome are discussed. The method, described in detail for the tmRNAs of Escherichia coli, Bacillus anthracis, and Caulobacter crescentus, is applicable to every tmRNA. Conclusion Improved molecular models of biological significance were obtained. These models will guide in the design of experiments and provide a better understanding of trans-translation. The comparative procedure described here for tmRNA is easily adopted for the modeling the members of other RNA families.

  7. 78 FR 52804 - mPower\\TM\\ Design-Specific Review Standard

    Science.gov (United States)

    2013-08-26

    ... COMMISSION mPower\\TM\\ Design-Specific Review Standard AGENCY: Nuclear Regulatory Commission. ACTION: Design-Specific Review Standard (DSRS) for the mPower\\TM\\ Design; re-opening of comment period. SUMMARY: On May 14... for the mPower\\TM\\ design (mPower\\TM\\ DSRS). The purpose of the mPower\\TM\\ DSRS is to more...

  8. Supporting Active User Involvment in Prototyping

    DEFF Research Database (Denmark)

    Grønbæk, Kaj

    1990-01-01

    development of prototypes to early evaluation of prototypes in envisioned use situations. Having users involved in such activities creates new requirements for tool support. Tools that support direct manipulation of prototypes and simulation of behaviour have shown promise for cooperative prototyping......The term prototyping has in recent years become a buzzword in both research and practice of system design due to a number of claimed advantages of prototyping techniques over traditional specification techniques. In particular it is often stated that prototyping facilitates the users' involvement...... in the development process. But prototyping does not automatically imply active user involvement! Thus a cooperative prototyping approach aiming at involving users actively and creatively in system design is proposed in this paper. The key point of the approach is to involve users in activities that closely couple...

  9. Inside Linden Lab: Second Life [TM] for Educators

    Science.gov (United States)

    Atkinson, Tom

    2008-01-01

    A new culture called Second Life [TM] has emerged that promises innovative strategies for everything from social interactions to business. Some educators believe it may hold new and unique opportunities for teaching and learning. Second Life [TM] (SL) is the creation of Linden Labs, a San Francisco-based corporation defined by its creators as "an…

  10. Study on Performance of Empore~(TM) Technetium Rad Disks

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    EmporeTM Technetium Rad disks produced by 3M Company contain GD-1 sorbent loaded on particles that are embedded in an inert PTFE matrix. In this study, several experiments have been accomplished to evaluate the performance of EmporeTM Technetium Rad disks.

  11. Utilising eduroam[TM] Architecture in Building Wireless Community Networks

    Science.gov (United States)

    Huhtanen, Karri; Vatiainen, Heikki; Keski-Kasari, Sami; Harju, Jarmo

    2008-01-01

    Purpose: eduroam[TM] has already been proved to be a scalable, secure and feasible way for universities and research institutions to connect their wireless networks into a WLAN roaming community, but the advantages of eduroam[TM] have not yet been fully discovered in the wireless community networks aimed at regular consumers. This aim of this…

  12. Full Immersive Virtual Environment Cave[TM] in Chemistry Education

    Science.gov (United States)

    Limniou, M.; Roberts, D.; Papadopoulos, N.

    2008-01-01

    By comparing two-dimensional (2D) chemical animations designed for computer's desktop with three-dimensional (3D) chemical animations designed for the full immersive virtual reality environment CAVE[TM] we studied how virtual reality environments could raise student's interest and motivation for learning. By using the 3ds max[TM], we can visualize…

  13. Performance of Landsat TM in ship detection in turbid waters

    NARCIS (Netherlands)

    Wu, G.; Leeuw, de J.; Skidmore, A.K.; Liu, Y.; Prins, H.H.T.

    2009-01-01

    The visible and near infrared bands of Landsat have limitations for detecting ships in turbid water. The potential of TM middle infrared bands for ship detection has so far not been investigated. This study analyzed the performance of the six Landsat TM visible and infrared bands for detecting dredg

  14. Accelerated Math[TM]. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2011

    2011-01-01

    "Accelerated Math"[TM], published by Renaissance Learning, is a software tool used to customize assignments and monitor progress in math for students in grades 1-12. The "Accelerated Math"[TM] software creates individualized assignments aligned with state standards and national guidelines, scores student work, and generates reports on student…

  15. SpellRead[TM]. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2013

    2013-01-01

    "SpellRead"[TM], formerly known as "SpellRead Phonological Auditory Training"[R], is a small-group literacy program for struggling readers in grades 2-12. "SpellRead"[TM] integrates the auditory and visual aspects of the reading process and emphasizes specific skill mastery through systematic and explicit instruction. Students are taught to…

  16. MRI tracheomalacia (TM) assessment in pediatric patients: feasibility study

    DEFF Research Database (Denmark)

    Ciet, P.; Wielopolski, P.; Lever, S.;

    2011-01-01

    Purpose: TM is an excessive narrowing of the intrathoracic part of the trachea. TM is a common congenital pediatric anomaly, but it’s often not recognized due to its unspecific clinical presentation. The aims of our study are: 1) to develop cine-MRI sequences to visualize central airways in static...

  17. Water quality mapping using Landsat TM imagery

    Science.gov (United States)

    Lim, H. S.; MatJafri, M. Z.; Abdullah, K.; Alias, A. N.; Wong, C. J.; Mustapha-Rosli, M. R.; Mohd Saleh, N.

    2009-05-01

    Environmental monitoring through the method of traditional ship sampling is time consuming and requires a high survey cost. The objective of this study is to evaluate the feasibility of Landsat TM imagery for total suspended solids (TSS) mapping using a newly developed algorithm over Penang Island. The study area is the seawater region around Penang Island, Malaysia. Water samples were collected during a 3-hour period simultaneously with the satellite image acquisition and later analyzed in the laboratory above the study area. The samples locations were determined using a handheld GPS. The satellite image was geometrically corrected using the second order polynomial transformation. The satellite image also was atmospheric corrected by using ATCOR2 image processing software. The digital numbers for each band corresponding to the sea-truth locations were extracted and then converted into reflectance values for calibration of the water quality algorithm. The proposed algorithm is based on the reflectance model that is a function of the inherent optical properties of water, which can be related to its constituent's concentrations. The generated algorithm was developed for three visible wavelenghts, red, green and blue for this study. Results indicate that the proposed developed algorithm was superior based on the correlation coefficient (R) and root-mean-square deviation (RMS) values. Finally the proposed algorithm was used for TSS mapping at Penang Island, Malaysia. The generated TSS map was colour-coded for visual interpretation and image smoothing was performed on the map to remove random noise. This preliminary study has produced a promising result. This study indicates that the empirical algorithm is suitable for TSS mapping around Penang Island by using satellite Landsat TM data.

  18. Sealing ability of grar MTA AngelusTM, CPM TM and MBPc used as apical plugs

    Directory of Open Access Journals (Sweden)

    Fernando Accorsi Orosco

    2008-02-01

    Full Text Available This study evaluated the sealing ability of apical plugs fabricated with gray MTA AngelusTM sealer, CPM TM sealer and MBPc sealer. The root canals of 98 extracted single-rooted human teeth were instrumented with #5 to #1 Gates Glidden drills according to the crown-down technique until the #1 drill could pass through the apical foramen. The specimens were then prepared with K-files, starting with an ISO 50 until an ISO 90 could be visualized 1 mm beyond the apex. After root canal preparation, the external surface of each root was rendered impermeable and roots were assigned to 3 experimental groups (n = 30, which received a 5-mm thick apical plug of gray MTA AngelusTM, CPM TM and MBPc, and two control groups (n=4. The remaining portion of the canal in the experimental groups was filled by the lateral condensation technique. The teeth of each group, properly identified, were fixed on utility wax by their crowns and were placed in plastic flasks, leaving the apex free and facing upward. The flasks were filled with 0.2% Rhodamine B solution, pH 7.0, so as to completely cover the root apex of all teeth. The sealing ability was analyzed by measuring 0.2% Rhodamine B leakage after all groups had been maintained in this solution for 48 hours. Data were analyzed statistically by Kruskal-Wallis test and Dunn test with a=5%. The results showed that, among the tested materials used for fabrication of apical plugs, MBPc sealer had the least amount of leakage with statistically significant difference (p<0.05.

  19. Prototyping the PANDA Barrel DIRC

    Energy Technology Data Exchange (ETDEWEB)

    Schwarz, C., E-mail: C.Schwarz@gsi.de [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany); Kalicy, G.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Hohler, R.; Kumawat, H.; Lehmann, D.; Lewandowski, B.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwiening, J.; Traxler, M.; Zühlsdorf, M. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt (Germany); Dodokhov, V.Kh. [Joint Institute for Nuclear Research, Dubna (Russian Federation); Britting, A.; Eyrich, W.; Lehmann, A. [Friedrich Alexander-University of Erlangen-Nuremberg, Erlangen (Germany); and others

    2014-12-01

    The design of the Barrel DIRC detector for the future PANDA experiment at FAIR contains several important improvements compared to the successful BABAR DIRC, such as focusing and fast timing. To test those improvements as well as other design options a prototype was build and successfully tested in 2012 with particle beams at CERN. The prototype comprises a radiator bar, focusing lens, mirror, and a prism shaped expansion volume made of synthetic fused silica. An array of micro-channel plate photomultiplier tubes measures the location and arrival time of the Cherenkov photons with sub-nanosecond resolution. The development of a fast reconstruction algorithm allowed to tune construction details of the detector setup with test beam data and Monte-Carlo simulations.

  20. Amino Acids in the TM4-TM5 loop of Na,K-ATPase Are Important for Biosynthesis

    DEFF Research Database (Denmark)

    Jørgensen, Jesper Roland; Houghton-Larsen, Jens; Jacobsen, Mette Dorph;

    2003-01-01

    in the endoplasmic reticulum quality control, as the same loop is responsible for the a-ß-associations required to leave this compartment. On the basis of the Ca-ATPase crystal structure and the presented data, we propose a model to account for the role of the TM4-TM5 loop in Na,K-ATPase biosynthesis....

  1. Prototyping DSU techniques using Python

    OpenAIRE

    Martinez, Sébastien; DAGNAT, Fabien; Buisson, Jérémy

    2013-01-01

    International audience This paper presents PyMoult, a Python library implementing various dynamic software update (DSU) mechanisms. This library aims to provide a prototyping platform for experimenting with DSU and to implement a vast choice of update mechanisms while allowing their combination and customization. We selected different update mechanisms from the literature and implemented them in PyMoult.This paper focuses on how we implemented these mechanisms and discusses the cost of imp...

  2. Rapid prototyping of robotic systems

    OpenAIRE

    Smuda, William James.

    2007-01-01

    This effort describes a systems engineering approach to the design and implementation of software for prototyping robotic systems. Developing networked robotic systems of diverse physical assets is a continuing challenge to developers. Problems often multiply when adding new hardware/software artifacts or when reconfiguring existing systems. This work describes a method to create model-based, graphical domain-specific languages. Domain-specific languages use terms understandable to domain...

  3. Results from the NEXT prototypes

    CERN Document Server

    Oliveira, C A B

    2013-01-01

    NEXT-100 is an electroluminescent high pressure Time Projection Chamber currently under construction. It will search for the neutrino-less double beta decay in 136Xe at the Canfranc Underground Laboratory. NEXT-100 aims to achieve nearly intrinsic energy resolution and to highly suppress background events by taking advantage of the unique properties of xenon in the gaseous phase as the detection medium. In order to prove the principle of operation and to study which are the best operational conditions, two prototypes were constructed: NEXT-DEMO and NEXT-DBDM. In this paper we present the latest results from both prototypes. We report the improvement in terms of light collection (?~3x?) achieved by coating the walls of NEXT-DEMO with tetraphenyl butadiene (TPB), the outstanding energy resolution of 1 % (Full Width Half Maximum) from NEXT-DBDM as well as the tracking capabilities of this prototype (2.1 mm RMS error for point-like depositions) achieved by using a square array of 8x8 SiPMs.

  4. Results from the NEXT prototypes

    Science.gov (United States)

    Oliveira, C. A. B.; NEXT Collaboration

    2013-10-01

    NEXT-100 is an electroluminescent high pressure Time Projection Chamber currently under construction. It will search for the neutrino-less double beta decay in 136Xe at the Canfranc Underground Laboratory. NEXT-100 aims to achieve nearly intrinsic energy resolution and to highly suppress background events by taking advantage of the unique properties of xenon in the gaseous phase as the detection medium. In order to prove the principle of operation and to study which are the best operational conditions, two prototypes were constructed: NEXT-DEMO and NEXT-DBDM. In this paper we present the latest results from both prototypes. We report the improvement in terms of light collection (~ 3×) achieved by coating the walls of NEXT-DEMO with tetraphenyl butadiene (TPB), the outstanding energy resolution of 1 % (Full Width Half Maximum) from NEXT-DBDM as well as the tracking capabilities of this prototype (2.1 mm RMS error for point-like depositions) achieved by using a square array of 8 × 8 SiPMs.

  5. Intracellular distribution of TM4SF1 and internalization of TM4SF1-antibody complex in vascular endothelial cells

    Energy Technology Data Exchange (ETDEWEB)

    Sciuto, Tracey E.; Merley, Anne; Lin, Chi-Iou [Center for Vascular Biology Research and Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School (United States); Richardson, Douglas [Department of Molecular and Cellular Biology, Harvard University (United States); Liu, Yu [Department of Pharmacology, Shanxi Medical University, Xinjiannanlu 56, Shanxi Province, Taiyuan 030001 (China); Li, Dan; Dvorak, Ann M. [Center for Vascular Biology Research and Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School (United States); Dvorak, Harold F., E-mail: hdvorak@bidmc.harvard.edu [Center for Vascular Biology Research and Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School (United States); Jaminet, Shou-Ching S., E-mail: sjaminet@bidmc.harvard.edu [Center for Vascular Biology Research and Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School (United States)

    2015-09-25

    Transmembrane-4 L-six family member-1 (TM4SF1) is a small plasma membrane-associated glycoprotein that is highly and selectively expressed on the plasma membranes of tumor cells, cultured endothelial cells, and, in vivo, on tumor-associated endothelium. Immunofluorescence microscopy also demonstrated TM4SF1 in cytoplasm and, tentatively, within nuclei. With monoclonal antibody 8G4, and the finer resolution afforded by immuno-nanogold transmission electron microscopy, we now demonstrate TM4SF1 in uncoated cytoplasmic vesicles, nuclear pores and nucleoplasm. Because of its prominent surface location on tumor cells and tumor-associated endothelium, TM4SF1 has potential as a dual therapeutic target using an antibody drug conjugate (ADC) approach. For ADC to be successful, antibodies reacting with cell surface antigens must be internalized for delivery of associated toxins to intracellular targets. We now report that 8G4 is efficiently taken up into cultured endothelial cells by uncoated vesicles in a dynamin-dependent, clathrin-independent manner. It is then transported along microtubules through the cytoplasm and passes through nuclear pores into the nucleus. These findings validate TM4SF1 as an attractive candidate for cancer therapy with antibody-bound toxins that have the capacity to react with either cytoplasmic or nuclear targets in tumor cells or tumor-associated vascular endothelium. - Highlights: • Anti-TM4SF1 antibody 8G4 was efficiently taken up by cultured endothelial cells. • TM4SF1–8G4 internalization is dynamin-dependent but clathrin-independent. • TM4SF1–8G4 complexes internalize along microtubules to reach the perinuclear region. • Internalized TM4SF1–8G4 complexes pass through nuclear pores into the nucleus. • TM4SF1 is an attractive candidate for ADC cancer therapy.

  6. Prototyping optimization in the web application development

    OpenAIRE

    Andrejak, Luka

    2016-01-01

    When developing web applications we often use prototyping. Prototyping allows us to involve end users of an application in early stages of development process, which can have positive effects on process itself. The correct interpretation of user feedback can avoid potential problems during development. The problem that often occurs in practice, are too simple prototypes that do not provide good simulation of the final application. One of the main principles of prototyping is rapid implementat...

  7. Prototypes in engineering design: Definitions and strategies

    DEFF Research Database (Denmark)

    Jensen, Lasse Skovgaard; Özkil, Ali Gürcan; Mortensen, Niels Henrik

    2016-01-01

    strategies. Due to rapid changes and progressions in the use of prototypes, we conclude conclude that there is a need for more holistic and overview generating research about prototyping. This for product developers to properly manage, select and apply the optimal prototyping process....

  8. Field Data Logger Prototype for Power Converters

    DEFF Research Database (Denmark)

    Chaudhary, Sanjay; Ghimire, Pramod; Thøgersen, Paul Bach;

    2014-01-01

    and subsequent analysis of the data. This paper presents the development of a low cost prototype field data logger prototype using Raspberry PI and industrial sensors. The functionalities of the data logger prototype are described. An online rainflow count algorithm has been implemented as well....

  9. Unified formalism for TE and TM beam propagators

    Science.gov (United States)

    Poladian, Leon; Ladouceur, Francois J.

    1998-07-01

    The unification of transverse electric (TE) and transverse magnetic (TM) beam propagation algorithms is made possible through a transformation which converts the wave equation for TM fields in planar waveguides into a form identical to the corresponding TE wave equation. The transformation can be applied to any smoothly varying waveguide. This transformation can be made independently of any paraxial or other approximations. Thus, any TE propagation algorithm can also be applied immediately to TM fields without additional approximations. This includes the classical fast Fourier transform beam propagator, which has not previously been applied successfully to TM propagation. We also specifically develop a Finite Difference Beam Propagation Method that applies to both TE and TM propagation in 1D (planar) geometry. Previous implementations for the TM case involve an approximation that in certain circumstances leads to severe errors (including the totally unphysical occurrence of field amplification). This is the first TM propagator which exactly conserves power. We also investigate the role of the reference background wavenumber (or index) and clarify its role as it is dynamically adapted. The algorithms proposed are easily adaptable to wide-angle beam propagators and to modern transparent boundary conditions. The extension of these ideas to rapidly varying structures (such as Bragg gratings) is also briefly discussed.

  10. Results from the FDIRC prototype

    International Nuclear Information System (INIS)

    We present results from a novel Cherenkov imaging detector called the Focusing DIRC (FDIRC). This detector was designed as a prototype of the particle identification system for the SuperB experiment, and comprises 1/12 of the SuperB barrel azimuthal coverage with partial electronics implementation. The prototype was tested in the SLAC Cosmic Ray Telescope (CRT) which provides 3-D muon tracking with an angular resolution of ∼1.5 mrad, track position resolution of 5–6 mm, start time resolution of 70 ps, and a muon low-energy cutoff of ∼2 GeV provided by an iron range stack. The quartz focusing photon camera couples to a full-size BaBar DIRC bar box and is read out by 12 Hamamatsu H8500 MaPMTs providing 768 pixels. We used IRS2 waveform digitizing electronics to read out the MaPMTs. We present several results from our on-going development activities that demonstrate that the new optics design works very well, including: (a) single photon Cherenkov angle resolutions with and without chromatic corrections, (b) S/N ratio between the Cherenkov peak and background, which consists primarily of ambiguities in possible photon paths to a given pixel, (c) dTOP=TOPmeasured–TOPexpected resolutions, and (d) performance of the detector in the presence of high-rate backgrounds. We also describe data analysis methods and point out limits of the present performance. - Highlights: • We present results from a novel Cherenkov imaging detector called the Focusing DIRC (FDIRC). • The prototype was tested in the SLAC Cosmic Ray Telescope (CRT) which provides 3-D muon tracking. • We present several results from our on-going development activities that demonstrate that new optics design works very well. • We describe data analysis methods and point out limits of the present performance

  11. Mechanical Prototyping and Manufacturing Internship

    Science.gov (United States)

    Grenfell, Peter

    2016-01-01

    The internship was located at the Johnson Space Center (JSC) Innovation Design Center (IDC), which is a facility where the JSC workforce can meet and conduct hands-on innovative design, fabrication, evaluation, and testing of ideas and concepts relevant to NASA's mission. The tasks of the internship included mechanical prototyping design and manufacturing projects in service of research and development as well as assisting the users of the IDC in completing their manufacturing projects. The first project was to manufacture hatch mechanisms for a team in the Systems Engineering and Project Advancement Program (SETMAP) hexacopter competition. These mechanisms were intended to improve the performance of the servomotors and offer an access point that would also seal to prevent cross-contamination. I also assisted other teams as they were constructing and modifying their hexacopters. The success of this competition demonstrated a proof of concept for aerial reconnaissance and sample return to be potentially used in future NASA missions. I also worked with Dr. Kumar Krishen to prototype an improved thermos and a novel, portable solar array. Computer-aided design (CAD) software was used to model the parts for both of these projects. Then, 3D printing as well as conventional techniques were used to produce the parts. These prototypes were then subjected to trials to determine the success of the designs. The solar array is intended to work in a cluster that is easy to set up and take down and doesn't require powered servomechanisms. It could be used terrestrially in areas not serviced by power grids. Both projects improve planetary exploration capabilities to future astronauts. Other projects included manufacturing custom rail brackets for EG-2, assisting engineers working on underwater instrument and tool cases for the NEEMO project, and helping to create mock-up parts for Space Center Houston. The use of the IDC enabled efficient completion of these projects at

  12. FY97 ICCS prototype specification

    Energy Technology Data Exchange (ETDEWEB)

    Woodruff, J.

    1997-02-20

    The ICCS software team will implement and test two iterations of their software product during FY97. The first of these iterations will concentrate on construction of selected framework components; the subsequent iteration will extend the product and perform measurements of performance based on emulated FEP devices. This document specifies the products to be delivered in that first prototype and projects the direction that the second prototype will take. Detailed specification of the later iteration will be written when the results of the first iteration are complete. The selection of frameworks to be implemented early is made on a basis of risk analysis from the point of view of future development in the ICCS project. The prototype will address risks in integration of object- oriented components, in refining our development process, and in emulation testing for FEP devices. This document is a specification that identifies products and processes to undertake for resolving these risks. The goals of this activity are to exercise our development process at a modest scale and to probe our architecture plan for fundamental limits and failure modes. The product of the iterations will be the framework software which will be useful in future ICCS code. Thus the FY97 products are intended for internal usage by the ICCS team and for demonstration to the FEP software developers of the strategy for integrating supervisory software with FEP computers. This will be the first of several expected iterations of the software development process and the performance measurements that ICCS will demonstrate, intended to support confidence in our ability to meet project RAM goals. The design of the application software is being carried out in a separate WBS 1.5.2 activity. The design activity has as its FY97 product a series of Software Design Documents that will specify the functionality of the controls software of ICCS. During the testing of this year`s prototypes, the application

  13. Landsat TM and ETM+ Kansas Satellite Image Database (KSID)

    Data.gov (United States)

    Kansas Data Access and Support Center — The Kansas Satellite Image Database (KSID):2000-2001 consists of terrain-corrected, precision rectified spring, summer, and fall Landsat 5 Thematic Mapper (TM) and...

  14. Ultrabroadband TM reflection from high contrast grating: why?

    NARCIS (Netherlands)

    Gushchin, I.; Tishchenko, A.V.; Parriaux, O.; Hoekstra, H.J.W.M.

    2009-01-01

    A grating mode analysis of the unusually broadband TM reflection from a high contrast binary grating sheds light on the origin of this effect. This interpretation will be submitted to the workshop attendance.

  15. Spectroscopic properties and laser performance of Tm:YAG ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Fei, B.J. [Key Lab of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002 (China); University of Chinese Academy of Sciences, Beijing 100039 (China); Huang, J.Q.; Guo, W.; Huang, Q.F. [Key Lab of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002 (China); Chen, J.; Tang, F. [Key Lab of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002 (China); University of Chinese Academy of Sciences, Beijing 100039 (China); Wang, W.C. [Department of Physics, Renmin University of China, Beijing 100872 (China); Cao, Y.G., E-mail: caoyongge@fjirsm.ac.cn [Key Lab of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002 (China); Department of Physics, Renmin University of China, Beijing 100872 (China)

    2013-10-15

    Tm:YAG laser ceramics were fabricated by solid-state reaction and simple vacuum sintering, and their spectroscopic characteristics were investigated in detail. High fluorescence quantum efficiency, long fluorescence lifetime and low up-conversion losses were demonstrated, which indicated that such ceramics could be used as laser gain media. Laser operation at 2 μm via {sup 3}F{sub 4}→{sup 3}H{sub 6} transition was realized. The maximum output power of 593 mW at 2007 nm was acquired with an optical conversion efficiency of 15.6%. -- Highlights: • Optical grade Tm:YAG laser ceramics were prepared. • Detail spectroscopic properties of Tm:YAG ceramic were investigated. • Cross-relaxation mechanisms of Tm{sup 3+} based on the emission spectra were elaborated. • Laser output of 593 mW was realized with an optical conversion efficiency of 15.6%.

  16. SynLam(TM) Primary Mirror Evaluation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group, Inc. (CRG), has developed sandwich core composite material (SynLam(TM)) and related fabrication technology to address the drawbacks of...

  17. Lightweight Metal RubberTM Sensors and Interconnects Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of this NASA Phase II program is to develop and increase the Technology Readiness Level of multifunctional Metal RubberTM (MRTM) materials that can be...

  18. Power system reliability enhancement by using PowerformerTM

    Directory of Open Access Journals (Sweden)

    Rahmat-Allah Hooshmand

    2009-01-01

    Full Text Available A high-voltage generator PowerformerTM is a new generation of the AC generators. The most significant advantages of these PowerformerTM are their direct connection to high-voltage grid, higher availability, and more reactive power margin, short term overloading capacity and removing the power transformer from the structure of the power plant. In this paper, the installation effect of these generators on the power system reliability is investigated. The amount of the effects depends on the type and location of the power plant, location of the PowerformerTM, the size of load and network topology. For this purpose, in the 6-bus IEEE RBTS system, the conventional generators are replaced by these new PowerformerTM and then, the reliability indices are evaluated. The simulation results show that the reliability indices such as the expected duration of load curtailment (EDLC and the expected energy not served (EENS are improved. .

  19. Tri-Decadal Global Landsat Orthorectified TM Scene V1

    Data.gov (United States)

    National Aeronautics and Space Administration — Abstract: The Landsat Orthorectified data collection consists of a global set of high-quality, relatively cloud-free orthorectified MSS, TM and ETM+ imagery from...

  20. GlossmarkTM Technology:An Innovative Digital Watermark

    Institute of Scientific and Technical Information of China (English)

    Beilei Xu; Shen-ge Wang; Chuheng Liu

    2004-01-01

    GlossmarkTM technology is a digital watermark process that embeds a visually striking gloss image within a high quality color print without the need of special papers or toners. It utilizes the angular dependence of gloss to create a differential-gloss image through the modulation of halftone structures. Both the primary image and the embedded GlossmarkTM image can be distinctively viewed from different perspectives with little interference. The strong directional nature of the gloss and the subtle halftone modulation process make GlossmarkTM images very difficult to detect by a scanner and even more challenging to reproduce through scanning and printing. The GlossmarkTM technology is ideally suitable for document authentication and graphics enhancement. Its digital implementation provides a capability to embed variable data as digital watermarks into individual prints quickly and economically.

  1. Tri-Decadal Global Landsat Orthorectified TM Mosaic V1

    Data.gov (United States)

    National Aeronautics and Space Administration — Abstract: The Landsat Orthorectified data collection consists of a global set of high-quality, relatively cloud-free orthorectified MSS, TM and ETM+ imagery from...

  2. Agile manufacturing prototyping system (AMPS)

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, P.

    1998-05-09

    The Agile Manufacturing Prototyping System (AMPS) is being integrated at Sandia National Laboratories. AMPS consists of state of the industry flexible manufacturing hardware and software enhanced with Sandia advancements in sensor and model based control; automated programming, assembly and task planning; flexible fixturing; and automated reconfiguration technology. AMPS is focused on the agile production of complex electromechanical parts. It currently includes 7 robots (4 Adept One, 2 Adept 505, 1 Staubli RX90), conveyance equipment, and a collection of process equipment to form a flexible production line capable of assembling a wide range of electromechanical products. This system became operational in September 1995. Additional smart manufacturing processes will be integrated in the future. An automated spray cleaning workcell capable of handling alcohol and similar solvents was added in 1996 as well as parts cleaning and encapsulation equipment, automated deburring, and automated vision inspection stations. Plans for 1997 and out years include adding manufacturing processes for the rapid prototyping of electronic components such as soldering, paste dispensing and pick-and-place hardware.

  3. Defects in Tm3+/Yb3+-doped YVO4 Crystals

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The microscopic defects have been investigated for crystal Tm3+/Yb3+:YVO4. These defects mainly include the inclusions (solid inclusions, bubbles and inclusions of the liquid phase), dendrites and growth stripes. They are caused by in-pure raw materials, unstable growth conditions, super-cooling component and so on. Tm3+/Yb3+:YVO4 crystals of large size and excellent optical quality are grown by improving the growth conditions to eliminate these defects.

  4. Laser desorption/ionization mass spectrometry on nanostructured semiconductor substrates: DIOS(TM) and QuickMass(TM)

    Science.gov (United States)

    Law, K. P.

    2010-02-01

    In the era of systems biology, new analytical platforms are under demand. Desorption/ionization on silicon mass spectrometry (DIOS-MS) is a promising high throughput laser mass spectrometry approach that has attracted a lot of attention, and has been commercialized. Another substrate material manufactured by physical method has also been made commercially available under the trade name of QuickMass(TM). These two commercial substrates, DIOS(TM) and QuickMass(TM), were investigated independently from the manufacturers and were characterized by a number of advanced surface techniques. This work determined (1) the correlation between the substrate physicochemical properties and their LDI activity, (2) the feasibility of metabolic profiling from complex biological matrices and (3) the laser desorption/ionization mechanism. The DIOS(TM) substrate was characterized with a thick nano-sized porous layer, a high surface concentration of fluorocarbon and silicon oxides and super-hydrophobicity. In contrast, the QuickMass(TM) substrate consisted of a non-porous germanium thin-film. The relatively high ionization efficiency obtained from the DIOS(TM) substrate was contributed to the fluorosilane manufacturing processes and its porous morphology. Despite the QuickMass(TM) substrate being less effective, it was noted that the use of germanium affords a self-cleaning mechanism and suppresses background interference of mass spectra. The suitability of DIOS(TM) substrates for metabolic profiling of complex biological matrices was demonstrated. DIOS mass spectra of human blood plasma, human urine and animal liver tissue extracts were produced. Suitable extraction methods were found to be important, but relatively simplified approaches were sufficient. Further investigations of the DIOS desorption/ionization mechanism were carried out. The previously proposed sub-surface state reaction could be a molten-solid interfacial state reaction of the substrate and this had a significant

  5. Prototype moving-ring reactor

    International Nuclear Information System (INIS)

    We have completed a design of the Prototype Moving-Ring Reactor. The fusion fuel is confined in current-carrying rings of magnetically-field-reversed plasma (Compact Toroids). The plasma rings, formed by a coaxial plasma gun, undergo adiabatic magnetic compression to ignition temperature while they are being injected into the reactor's burner section. The cylindrical burner chamber is divided into three burn stations. Separator coils and a slight axial guide field gradient are used to shuttle the ignited toroids rapidly from one burn station to the next, pausing for 1/3 of the total burn time at each station. D-T-3He ice pellets refuel the rings at a rate which maintains constant radiated power

  6. Sonification Prototype for Space Physics

    Science.gov (United States)

    Candey, R. M.; Schertenleib, A. M.; Diaz Merced, W. L.

    2005-12-01

    As an alternative and adjunct to visual displays, auditory exploration of data via sonification (data controlled sound) and audification (audible playback of data samples) is promising for complex or rapidly/temporally changing visualizations, for data exploration of large datasets (particularly multi-dimensional datasets), and for exploring datasets in frequency rather than spatial dimensions (see also International Conferences on Auditory Display ). Besides improving data exploration and analysis for most researchers, the use of sound is especially valuable as an assistive technology for visually-impaired people and can make science and math more exciting for high school and college students. Only recently have the hardware and software come together to make a cross-platform open-source sonification tool feasible. We have developed a prototype sonification data analysis tool using the JavaSound API and NASA GSFC's ViSBARD software . Wanda Diaz Merced, a blind astrophysicist from Puerto Rico, is instrumental in advising on and testing the tool.

  7. The EUROMEDIES EDI prototype system.

    Science.gov (United States)

    Pramataris, K; Doukidis, G; Giaglis, G; Raptakis, J

    1996-01-01

    EDI is expected to be the dominant form of business communication between organisations moving to the Electronic Commerce era of 2000. The healthcare sector is already using EDI in the hospital supply function as well as in the clinical area and the reimbursement process. In this paper, we examine the use of EDI in the healthcare administration sector and move specifically its application to the Medical Devices Vigilance System. At a first place, the potential of this approach is examined, after an initial brief presentation of the EDI concept and its application in healthcare. This presentation is followed by an overall description of the EDI prototype system, which was developed in the context of the EUROMEDIES Concerted Action, in order to facilitate the requirements definition phase. PMID:10172831

  8. Prototype international quality assurance program

    International Nuclear Information System (INIS)

    The international community presently lacks the ability to determine the quality and credibility of environmental measurements that is required to make sound decisions in matters related to international security, public health, and investment-related considerations. The ultimate goal of the work described in this article is to develop a credible information base including measurement capability for determination of environmental contamination and the potential for proliferation of material components of chemical or nuclear weapons. This study compared the accuracy obtained by six Russian and six U.S. laboratories for samples representative of classes of trace metals, dioxing-furans, and radioactive substances. The results obtained in this work indicate that current estimates for laboratory accuracy are likely overly optimistic. The weaknesses discovered by this prototype U.S. - Russia study also exist within the broader international community of laboratories. Further work is proposed to address the urgent need for the international community to improve performance evaluations for analytical measurements. (author)

  9. Hadron therapy information sharing prototype

    CERN Document Server

    Roman, Faustin Laurentiu; Kanellopoulos, Vassiliki; Amoros, Gabriel; Davies, Jim; Dosanjh, Manjit; Jena, Raj; Kirkby, Norman; Peach, Ken; Salt, Jose

    2013-01-01

    The European PARTNER project developed a prototypical system for sharing hadron therapy data. This system allows doctors and patients to record and report treatment-related events during and after hadron therapy. It presents doctors and statisticians with an integrated view of adverse events across institutions, using open-source components for data federation, semantics, and analysis. There is a particular emphasis upon semantic consistency, achieved through intelligent, annotated form designs. The system as presented is ready for use in a clinical setting, and amenable to further customization. The essential contribution of the work reported here lies in the novel data integration and reporting methods, as well as the approach to software sustainability achieved through the use of community-supported open-source components.

  10. Prototype of industrial electrons accelerator

    International Nuclear Information System (INIS)

    The interest and the necessity of Mexico's industry in the use of irradiation process has been increased in the last years. As examples are the irradiation of combustion gases (elimination of NOx and SO2) and the polymer cross-linking between others. At present time at least twelve enterprises require immediately of them which have been contacted by electron accelerators suppliers of foreign countries. The first project step consisted in to identify the electrons accelerator type that in can be constructed in Mexico with the major number of possible equipment, instruments, components and acquisition materials local and useful for the major number of users. the characteristics of the accelerator prototype are: accelerator type transformer with multiple secondary insulated and rectifier circuits with a potential of 0.8 MV of voltage, the second step it consisted in an economic study that permitted to demonstrate the economic feasibility of its construction. (Author)

  11. LEP vacuum chamber, early prototype

    CERN Multimedia

    1978-01-01

    The structure of LEP, with long bending magnets and little access to the vacuum chamber between them, required distributed pumping. This is an early prototype for the LEP vacuum chamber, made from extruded aluminium. The main opening is for the beam. The small channel to the right is for cooling water, to carry away the heat deposited by the synchroton radiation from the beam. The 4 slots in the channel to the left house the strip-shaped ion-getter pumps (see 7810255). The ion-getter pumps depended on the magnetic field of the bending magnets, too low at injection energy for the pumps to function well. Also, a different design was required outside the bending magnets. This design was therefore abandoned, in favour of a thermal getter pump (see 8301153 and 8305170).

  12. Prototype calorimeters for the NA3 experiment

    CERN Multimedia

    1975-01-01

    The NA3 Experiment was set-up on the North Area of the SPS by the CERN/ Ecole Polytechnique/College de France/ Orsay/Saclay Collaboration, to study high transverse momentum leptons and hadrons from hadron collisions. The calorimeters measured the energy of hadrons (prototype on the right) and leptons (prototype on the left). They used a new type of plastic scintillator (plexipop). (see CERN Courier of November 1975) energy (prototype on the right)

  13. Monophonic Instrument Playing Practice System Prototype

    OpenAIRE

    Haarahiltunen, Mika

    2013-01-01

    The goal of the project was to develop a prototype of a system that could be used for practicing the playing of breath instruments, such as flutes or saxophones. However, during the development process, the emphasis shifted from a breath instrument specific design towards a more generic design that could be used with any monophonic instrument. The development of the prototype included studying existing solutions, specifying the functional requirements and finally implementing the prototype. T...

  14. Human resources and wage package (Generalist{sub TM}); Jinji kyuyo package (Generalist{sub TM})

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The Generalist{sub TM} is an enterprise resource planning (ERP) package to manage human resource information as the property for an enterprise and calculate wages. Enterprises are making efforts to improve the management efficiency in recent years, and put up effective human resource arrangements and utilization, and structuring new wage systems intended of appropriate remuneration. There is a rapid movement to switch the conventional systems structured independently based on general purpose large computers and office computers into packages in open environment by using UNIX and Windows NT(reg sign). The present package is enjoying the growing sales since the release of the first edition in April 1998. It is intended to continue strengthening the functions aiming at achieving the industry's No. 1 package by releasing in April 2000 the version 2.0 that operates on web top. (translated by NEDO)

  15. Cryo-electron Microscopy Structure of the Native Prototype Foamy Virus Glycoprotein and Virus Architecture.

    Science.gov (United States)

    Effantin, Grégory; Estrozi, Leandro F; Aschman, Nick; Renesto, Patricia; Stanke, Nicole; Lindemann, Dirk; Schoehn, Guy; Weissenhorn, Winfried

    2016-07-01

    Foamy viruses (FV) belong to the genus Spumavirus, which forms a distinct lineage in the Retroviridae family. Although the infection in natural hosts and zoonotic transmission to humans is asymptomatic, FVs can replicate well in human cells making it an attractive gene therapy vector candidate. Here we present cryo-electron microscopy and (cryo-)electron tomography ultrastructural data on purified prototype FV (PFV) and PFV infected cells. Mature PFV particles have a distinct morphology with a capsid of constant dimension as well as a less ordered shell of density between the capsid and the membrane likely formed by the Gag N-terminal domain and the cytoplasmic part of the Env leader peptide gp18LP. The viral membrane contains trimeric Env glycoproteins partly arranged in interlocked hexagonal assemblies. In situ 3D reconstruction by subtomogram averaging of wild type Env and of a Env gp48TM- gp80SU cleavage site mutant showed a similar spike architecture as well as stabilization of the hexagonal lattice by clear connections between lower densities of neighboring trimers. Cryo-EM was employed to obtain a 9 Å resolution map of the glycoprotein in its pre-fusion state, which revealed extensive trimer interactions by the receptor binding subunit gp80SU at the top of the spike and three central helices derived from the fusion protein subunit gp48TM. The lower part of Env, presumably composed of interlaced parts of gp48TM, gp80SU and gp18LP anchors the spike at the membrane. We propose that the gp48TM density continues into three central transmembrane helices, which interact with three outer transmembrane helices derived from gp18LP. Our ultrastructural data and 9 Å resolution glycoprotein structure provide important new insights into the molecular architecture of PFV and its distinct evolutionary relationship with other members of the Retroviridae. PMID:27399201

  16. Cryo-electron Microscopy Structure of the Native Prototype Foamy Virus Glycoprotein and Virus Architecture.

    Directory of Open Access Journals (Sweden)

    Grégory Effantin

    2016-07-01

    Full Text Available Foamy viruses (FV belong to the genus Spumavirus, which forms a distinct lineage in the Retroviridae family. Although the infection in natural hosts and zoonotic transmission to humans is asymptomatic, FVs can replicate well in human cells making it an attractive gene therapy vector candidate. Here we present cryo-electron microscopy and (cryo-electron tomography ultrastructural data on purified prototype FV (PFV and PFV infected cells. Mature PFV particles have a distinct morphology with a capsid of constant dimension as well as a less ordered shell of density between the capsid and the membrane likely formed by the Gag N-terminal domain and the cytoplasmic part of the Env leader peptide gp18LP. The viral membrane contains trimeric Env glycoproteins partly arranged in interlocked hexagonal assemblies. In situ 3D reconstruction by subtomogram averaging of wild type Env and of a Env gp48TM- gp80SU cleavage site mutant showed a similar spike architecture as well as stabilization of the hexagonal lattice by clear connections between lower densities of neighboring trimers. Cryo-EM was employed to obtain a 9 Å resolution map of the glycoprotein in its pre-fusion state, which revealed extensive trimer interactions by the receptor binding subunit gp80SU at the top of the spike and three central helices derived from the fusion protein subunit gp48TM. The lower part of Env, presumably composed of interlaced parts of gp48TM, gp80SU and gp18LP anchors the spike at the membrane. We propose that the gp48TM density continues into three central transmembrane helices, which interact with three outer transmembrane helices derived from gp18LP. Our ultrastructural data and 9 Å resolution glycoprotein structure provide important new insights into the molecular architecture of PFV and its distinct evolutionary relationship with other members of the Retroviridae.

  17. Enhancing experience prototyping by the help of mixed-fidelity prototypes

    OpenAIRE

    Yasar, Ansar-Ul-Haque

    2007-01-01

    In this research review I undertook the problem related to the usage of a new concept known as the Mixed- Fidelity Prototype which is a mixture of its predecessors Low- and High- Fidelity Prototypes in Experience Prototyping. Experience Prototyping is a good way to explore, communicate and interact with the designs we develop like experiencing cycling on the ice, although the mood, snow conditions, bicycle type and many other factors really matter and tend to change with time. Experience Prot...

  18. Dissipative Prototyping Methods: A Manifesto

    Science.gov (United States)

    Beesley, P.

    Taking a designer's unique perspective using examples of practice in experimental installation and digital protoyping, this manifesto acts as provocation for change and unlocking new potential by encouraging changes of perspective about the material realm. Diffusive form-language is proposed as a paradigm for architectural design. This method of design is applied through 3D printing and related digital fabrication methods, offering new qualities that can be implemented in design of realms including present earth and future interplanetary environments. A paradigm shift is encouraged by questioning conventional notions of geometry that minimize interfaces and by proposing the alternatives of maximized interfaces formed by effusive kinds of formal composition. A series of projects from the Canadian research studio of the Hylozoic Architecture group are described, providing examples of component design methods employing diffusive forms within combinations of tension-integrity structural systems integrated with hybrid metabolisms employing synthetic biology. Cultural implications are also discussed, drawing from architectural theory and natural philosophy. The conclusion of this paper suggests that the practice of diffusive prototyping can offer formative strategies contributing to design of future living systems.

  19. Wireless Augmented Reality Prototype (WARP)

    Science.gov (United States)

    Devereaux, A. S.

    1999-01-01

    Initiated in January, 1997, under NASA's Office of Life and Microgravity Sciences and Applications, the Wireless Augmented Reality Prototype (WARP) is a means to leverage recent advances in communications, displays, imaging sensors, biosensors, voice recognition and microelectronics to develop a hands-free, tetherless system capable of real-time personal display and control of computer system resources. Using WARP, an astronaut may efficiently operate and monitor any computer-controllable activity inside or outside the vehicle or station. The WARP concept is a lightweight, unobtrusive heads-up display with a wireless wearable control unit. Connectivity to the external system is achieved through a high-rate radio link from the WARP personal unit to a base station unit installed into any system PC. The radio link has been specially engineered to operate within the high- interference, high-multipath environment of a space shuttle or space station module. Through this virtual terminal, the astronaut will be able to view and manipulate imagery, text or video, using voice commands to control the terminal operations. WARP's hands-free access to computer-based instruction texts, diagrams and checklists replaces juggling manuals and clipboards, and tetherless computer system access allows free motion throughout a cabin while monitoring and operating equipment.

  20. A prototype space flight intravenous injection system

    Science.gov (United States)

    Colombo, G. V.

    1985-01-01

    Medical emergencies, especially those resulting from accidents, frequently require the administration of intravenous fluids to replace lost body liquids. The development of a prototype space flight intravenous injection system is presented. The definition of requirements, injectable concentrates development, water polisher, reconstitution hardware development, administration hardware development, and prototype fabrication and testing are discussed.

  1. Project management strategies for prototyping breakdowns

    DEFF Research Database (Denmark)

    Granlien, Maren Sander; Pries-Heje, Jan; Baskerville, Richard

    2009-01-01

    Prototyping is often presented as a universal solution to many intractable information systems project problems. Prototyping is known to offer at least three advantages (1) provide users with a concrete understanding, (2) eliminate the confusion, (3) cope with uncertainty. On the other hand...... to partial recovery of the project but not until several coping strategies had been tried....

  2. Comparative evaluation of two methods for 172Tm production in nuclear reactors

    International Nuclear Information System (INIS)

    A comparative evaluation of two methods for the production of 172Tm in nuclear reactors is carried out. They are respectively based on two chains of double neutron capture reactions, 170Er(n,γ)171Er(n,γ)172Er(β-)172Tm and 170Er(n,γ)171Er(β-)171Tm(n,γ)172Tm, and a chain of triple neutron capture: 169Tm(n,γ)170Tm(n,γ)71Tm(n,γ)172Tm. Theoretical considerations with respect to both ways of production are formulated and the mathematical equation are solved. Experiments of irradiation of Er2O3 and Tm2O3 were performed. Advantages and drawbacks of both methods are discussed. (author)

  3. Virtual video prototyping of pervasive healthcare systems

    DEFF Research Database (Denmark)

    Bardram, Jakob; Bossen, Claus; Lykke-Olesen, Andreas;

    2002-01-01

    issues, since one cannot avoid paying attention to the physical, real-world constraints and to details in the usage-interaction between users and technology. From the users' perspective, during our evaluation of the virtual video prototype, we experienced how it enabled users to relate......Virtual studio technology enables the mixing of physical and digital 3D objects and thus expands the way of representing design ideas in terms of virtual video prototypes, which offers new possibilities for designers by combining elements of prototypes, mock-ups, scenarios, and conventional video....... In this article we report our initial experience in the domain of pervasive healthcare with producing virtual video prototypes and using them in a design workshop. Our experience has been predominantly favourable. The production of a virtual video prototype forces the designers to decide very concrete design...

  4. Virtual Video Prototyping for Healthcare Systems

    DEFF Research Database (Denmark)

    Bardram, Jakob Eyvind; Bossen, Claus; Lykke-Olesen, Andreas;

    2002-01-01

    Virtual studio technology enables the mixing of physical and digital 3D objects and thus expands the way of representing design ideas in terms of virtual video prototypes, which offers new possibilities for designers by combining elements of prototypes, mock-ups, scenarios, and conventional video...... concrete design issues, since one cannot avoid paying attention to the physical, real-world constraints and to details in the usage-interaction between users and technology. From the users' perspective, during our evaluation of the virtual video prototype, we experienced how it enabled users to relate to....... In this article we report our initial experience in the domain of pervasive healthcare with producing virtual video prototypes and using them in a design workshop. Our experience has been predominantly favourable. The production of a virtual video prototype forces the designers to decide very...

  5. Powernext Day-AheadTM products and market organization

    International Nuclear Information System (INIS)

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing the French power exchange through an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-AheadTM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext FuturesTM since 18 June 2004. This document presents the principle of the trading of hourly contracts on Powernext Day-AheadTM, the accessibility of the market, the SAPRI trading platform operated by Nord Pool, the Scandinavian power exchange, the validation of the auction results, the collaboration with LCH.Clearnet SA to secure and facilitate the transactions, and the delivery guarantee implemented by RTE (the French energy transport network). (J.S.)

  6. Spectroscopic analysis of LiTmF4

    DEFF Research Database (Denmark)

    Christensen, H.P.

    1979-01-01

    The absorption spectra of Tm3+ in LiTmF4 have been measured at 2, 10, 30, and 50 K in the spectral interval 4000-25 000 cm-1. The energy levels of the ground-state configuration were calculated by diagonalizing the Hamiltonian of the electron-electron interaction, the spin-orbit coupling...... effects, it was necessary after optimizing F2 and ζ to match the centers of gravity for the multiplets before the final adjustment of the B parameters. When this was done, the standard deviation was lowered from 170 to 12 cm-1. The B parameters obtained for Tm3+ have been compared to those of Tb3+, Ho3...

  7. Construction of covalently coupled, concatameric dimers of 7TM receptors

    DEFF Research Database (Denmark)

    Terpager, Marie; Scholl, D Jason; Kubale, Valentina;

    2009-01-01

    -Ala repeats flanked by flexible spacers and positively charged residues to ensure correct inside-out orientation plus an extracellular HA-tag to construct covalently coupled dimers of 7TM receptors. Such 15 TM concatameric homo- and heterodimers of the beta(2)-adrenergic and the NK(1) receptors, which...... normally do not dimerize with each other, were expressed surprisingly well at the cell surface, where they bound ligands and activated signal transduction in a manner rather similar to the corresponding wild-type receptors. The concatameric heterodimers internalized upon stimulation with agonists...

  8. Optical transitions and up-conversion emission of Tm3+-singly doped and Tm3+/Yb3+-codoped oxyfluoride glasses

    International Nuclear Information System (INIS)

    Novel oxyfluoride glasses SiO2-Al2O3-Na2O-ZnF2 doped with Tm3+ and Tm3+/Yb3+ were fabricated. The optical properties of the synthesized glasses were experimentally and theoretically investigated in detail. According to the Judd-Ofelt theory, the Judd-Ofelt intensity parameters were calculated. With these intensity parameters, the radiative transition probabilities, fluorescence branching ratios and radiative lifetimes were obtained. The fluorescence lifetime and quantum efficiency for 1D2→3F4 emission of Tm3+-singly doped glass were determined to be 12 μs, and 35.3%, respectively. The up-conversion luminescence was observed upon excitation with 980 nm diode laser. The dependence of the up-conversion emission intensity upon the excitation power was examined, and the up-conversion mechanisms were discussed

  9. Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation

    DEFF Research Database (Denmark)

    Nygaard, Rie; Hansen, Louise Valentin; Mokrosinski, Jacek;

    2010-01-01

    Five highly conserved polar residues connected by a number of structural water molecules together with two rotamer micro-switches, TrpVI:13 and TyrVII:20, constitute an extended hydrogen bond network between the intracellular segments of TM-I, -II, -VI, and -VII of 7TM receptors. Molecular dynamics...... to apparently function as a catching trap for water molecules. Mutational analysis of the beta2-adrenergic receptor demonstrated that the highly conserved polar residues of the hydrogen bond network were all important for receptor signaling but served different functions, some dampening constitutive activity...... (AsnI:18, AspII:10, and AsnVII:13), whereas others (AsnVII:12 and AsnVII:16) located one helical turn apart and sharing a water molecule were shown to be essential for agonist-induced signaling. It is concluded that the conserved water hydrogen bond network of 7TM receptors constitutes an extended...

  10. Review on CNC-Rapid Prototyping

    Science.gov (United States)

    Z, M. Nafis O.; Y, Nafrizuan M.; A, Munira M.; J, Kartina

    2012-09-01

    This article reviewed developments of Computerized Numerical Control (CNC) technology in rapid prototyping process. Rapid prototyping (RP) can be classified into three major groups; subtractive, additive and virtual. CNC rapid prototyping is grouped under the subtractive category which involves material removal from the workpiece that is larger than the final part. Richard Wysk established the use of CNC machines for rapid prototyping using sets of 2½-D tool paths from various orientations about a rotary axis to machine parts without refixturing. Since then, there are few developments on this process mainly aimed to optimized the operation and increase the process capabilities to stand equal with common additive type of RP. These developments include the integration between machining and deposition process (hybrid RP), adoption of RP to the conventional machine and optimization of the CNC rapid prototyping process based on controlled parameters. The article ended by concluding that the CNC rapid prototyping research area has a vast space for improvement as in the conventional machining processes. Further developments and findings will enhance the usage of this method and minimize the limitation of current approach in building a prototype.

  11. Review on CNC-Rapid Prototyping

    International Nuclear Information System (INIS)

    This article reviewed developments of Computerized Numerical Control (CNC) technology in rapid prototyping process. Rapid prototyping (RP) can be classified into three major groups; subtractive, additive and virtual. CNC rapid prototyping is grouped under the subtractive category which involves material removal from the workpiece that is larger than the final part. Richard Wysk established the use of CNC machines for rapid prototyping using sets of 2½-D tool paths from various orientations about a rotary axis to machine parts without refixturing. Since then, there are few developments on this process mainly aimed to optimized the operation and increase the process capabilities to stand equal with common additive type of RP. These developments include the integration between machining and deposition process (hybrid RP), adoption of RP to the conventional machine and optimization of the CNC rapid prototyping process based on controlled parameters. The article ended by concluding that the CNC rapid prototyping research area has a vast space for improvement as in the conventional machining processes. Further developments and findings will enhance the usage of this method and minimize the limitation of current approach in building a prototype.

  12. Rapid prototyping and stereolithography in dentistry

    Directory of Open Access Journals (Sweden)

    Sanjna Nayar

    2015-01-01

    Full Text Available The word rapid prototyping (RP was first used in mechanical engineering field in the early 1980s to describe the act of producing a prototype, a unique product, the first product, or a reference model. In the past, prototypes were handmade by sculpting or casting, and their fabrication demanded a long time. Any and every prototype should undergo evaluation, correction of defects, and approval before the beginning of its mass or large scale production. Prototypes may also be used for specific or restricted purposes, in which case they are usually called a preseries model. With the development of information technology, three-dimensional models can be devised and built based on virtual prototypes. Computers can now be used to create accurately detailed projects that can be assessed from different perspectives in a process known as computer aided design (CAD. To materialize virtual objects using CAD, a computer aided manufacture (CAM process has been developed. To transform a virtual file into a real object, CAM operates using a machine connected to a computer, similar to a printer or peripheral device. In 1987, Brix and Lambrecht used, for the first time, a prototype in health care. It was a three-dimensional model manufactured using a computer numerical control device, a type of machine that was the predecessor of RP. In 1991, human anatomy models produced with a technology called stereolithography were first used in a maxillofacial surgery clinic in Viena.

  13. Rapid prototyping and stereolithography in dentistry.

    Science.gov (United States)

    Nayar, Sanjna; Bhuminathan, S; Bhat, Wasim Manzoor

    2015-04-01

    The word rapid prototyping (RP) was first used in mechanical engineering field in the early 1980s to describe the act of producing a prototype, a unique product, the first product, or a reference model. In the past, prototypes were handmade by sculpting or casting, and their fabrication demanded a long time. Any and every prototype should undergo evaluation, correction of defects, and approval before the beginning of its mass or large scale production. Prototypes may also be used for specific or restricted purposes, in which case they are usually called a preseries model. With the development of information technology, three-dimensional models can be devised and built based on virtual prototypes. Computers can now be used to create accurately detailed projects that can be assessed from different perspectives in a process known as computer aided design (CAD). To materialize virtual objects using CAD, a computer aided manufacture (CAM) process has been developed. To transform a virtual file into a real object, CAM operates using a machine connected to a computer, similar to a printer or peripheral device. In 1987, Brix and Lambrecht used, for the first time, a prototype in health care. It was a three-dimensional model manufactured using a computer numerical control device, a type of machine that was the predecessor of RP. In 1991, human anatomy models produced with a technology called stereolithography were first used in a maxillofacial surgery clinic in Viena.

  14. Transition intensities and excited state relaxation dynamics of Tm3+ in Tm:PbF2 crystal

    Science.gov (United States)

    Yin, J. G.; Hang, Y.; He, X. H.; Zhang, L. H.; Zhao, C. C.; Ma, E.; Gong, J.; Zhang, P. G.

    2012-03-01

    High-quality Tm doped β-PbF2 crystal is grown by the Bridgman method in a nonvacuum atmosphere. Optical absorption spectra were acquired and analysed in the framework of the Judd-Ofelt theory. Values of radiative transition rates and luminescence branching ratios calculated using phenomenological intensity parameters Ωλ were compared to corresponding experimental values derived from measurement of luminescence spectra and decay curves. The emission cross-sections of the 3 F 4 → 3 H 6 transitions of the Tm3+ ions at 1.86 μm wavelengths were estimated by the use of the Fuchtbauer-Ladengurg method.

  15. Evaluation of a prototype infrasound system

    International Nuclear Information System (INIS)

    Under Department of Energy sponsorship, Sandia National Laboratories and Los Alamos National Laboratory cooperated to develop a prototype infrasonic array, with associated documentation, that could be used as part of the International Monitoring System. The United States Government or foreign countries could procure commercially available systems based on this prototype to fulfill their Comprehensive Test Ban Treaty (CTBT) obligations. The prototype is a four-element array in a triangular layout as recommended in CD/NTB/WP.224 with an element at each corner and one in the center. The prototype test configuration utilize an array spacing of 1 km. The prototype infrasound system has the following objectives: (1) Provide a prototype that reliably acquires and transmits near real-time infrasonic data to facilitate the rapid location and identification of atmospheric events. (2) Provide documentation that could be used by the United States and foreign countries to procure infrasound systems commercially to fulfill their CTBT responsibilities. Infrasonic monitoring is an effective, low cost technology for detecting atmospheric explosions. The low frequency components of explosion signals propagate to long ranges (few thousand kilometers) where they can be detected with an array of sensors. Los Alamos National Laboratory's expertise in infrasound systems and phenomenology when combined with Sandia's expertise in providing verification quality system for treaty monitoring make an excellent team to provide the prototype infrasound sensor system. By September 1997, the prototype infrasound system will have been procured, integrated, evaluated and documented. Final documentation will include a system requirements document, an evaluation report and a hardware design document. The hardware design document will describe the various hardware components used in the infrasound prototype and their interrelationships

  16. The four INTA-300 rocket prototypes

    Science.gov (United States)

    Calero, J. S.

    1985-03-01

    A development history and performance capability assessment is presented for the INTA-300 'Flamenco' sounding rocket prototype specimens. The Flamenco is a two-stage solid fuel rocket, based on British sounding rocket technology, that can lift 50 km payloads to altitudes of about 300 km. The flight of the first two prototypes, in 1974 and 1975, pointed to vibration problems which reduced the achievable apogee, and the third prototype's flight was marred by a premature detonation that destroyed the rocket. The fourth Flamenco flight, however, yielded much reliable data.

  17. On the neutron jet prototype

    International Nuclear Information System (INIS)

    Full text: Fast neutrons are proposed to use, in a deep space, as a recoil mass for low-thrust nuclear fission (or fusion) rocket engine instead of hydrogen heated in nuclear reactor up to 2300 - 2700oC [1, 2]. In particularly, such neutron engines with a long-term operation as well as nuclear powerful or micro-explosions can be used for ensuring of the astronomical safety for the Earth from asteroids in diameter more 50 m. For production of attractive force of 9.81N the propellant expenditure of hydrogen jet with the system specific impulse of ∼ 9000 m s-1 is ∼ 94 kg a day. For fast 1.8 MeV-neutron jet - 45.8 g per day (directed or collimated neutron fluxes). J=1016cm-2 s-1 if a cross-section of rocket nozzle is 1m2 [2]. So, to produce powerful directed or collimated fast neutron fluxes high intensity controlled neutron sources are required (they are, basically, the novel high-flux research reactors, for example, HFRR (Osaka University, Japan), 400 MW (th) and ψ=1016 cm-2 s-1). The most suitable neutron jet prototype is the B-2 facility of the fast reactor BR-5 (SSC RF Obninsk, Russia). This is a 'mono directional disk' with a diameter of 0.25 m; for neutrons with energies > (2, 3) MeV the collimated neutron flux is 1010cm-2 s-1 at the reactor power of 5 MW [3]. The intensification of fast neutron fluences may be up to ∼ 21 for the volume fast neutron source (the fast reactor with a diameter of ∼ 0.8 m) and ∼ 39 for point one by using an iron reflecting tube one side of which is closed (end wall - the effects of a neutron searchlight) [4]. The thickness of walls is 40 cm [5]. The additional intensification is possible by using 6LiD-thermal neutron-flux converter into ∼ 14 MeV-neutrons from (dT), (6LiT)-fusion reactions [6

  18. Characterization of Prototype LSST CCDs

    Energy Technology Data Exchange (ETDEWEB)

    OCONNOR,P.; FRANK, J.; GEARY, J.C.; GILMORE, D.K.; KOTOV, I.; RADEKA, V.; TAKACS, P.; TYSON, J.A.

    2008-06-23

    The ambitious science goals of the Large Synoptic Survey Telescope (LSST) will be achieved in part by a wide-field imager that will achieve a new level of performance in terms of area, speed, and sensitivity. The instrument performance is dominated by the focal plane sensors, which are now in development. These new-generation sensors will make use of advanced semiconductor technology and will be complemented by a highly integrated electronics package located inside the cryostat. A test laboratory has been set up at Brookhaven National Laboratory (BNL) to characterize prototype sensors and to develop test and assembly techniques for eventual integration of production sensors and electronics into modules that will form the final focal plane. As described in [1], the key requirements for LSST sensors are wideband quantum efficiency (QE) extending beyond lpm in the red, control of point spread function (PSF), and fast readout using multiple amplifiers per chip operated in parallel. In addition, LSST's fast optical system (f71.25) places severe constraints on focal plane flatness. At the chip level this involves packaging techniques to minimize warpage of the silicon die, and at the mosaic level careful assembly and metrology to achieve a high coplanarity of the sensor tiles. In view of the long lead time to develop the needed sensor technology, LSST undertook a study program with several vendors to fabricate and test devices which address the most critical performance features [2]. The remainder of this paper presents key results of this study program. Section 2 summarizes the sensor requirements and the results of design optimization studies, and Section 3 presents the sensor development plan. In Section 4 we describe the test bench at BNL. Section 5 reports measurement results obtained to date oh devices fabricated by several vendors. Section 6 presents a summary of the paper and an outlook for the future work. We present characterization methods and results on

  19. Tm2+ luminescent materials for solar radiation conversion devices

    NARCIS (Netherlands)

    Van der Kolk, E.

    2015-01-01

    A solar radiation conversion device is described that comprises a luminescent Tm 2+ inorganic material for converting solar radiation of at least part of the UV and/or visible and/or infra red solar spectrum into infrared solar radiation, preferably said infrared solar radiation having a wavelength

  20. An Excel[TM] Model of a Radioactive Series

    Science.gov (United States)

    Andrews, D. G. H.

    2009-01-01

    A computer model of the decay of a radioactive series, written in Visual Basic in Excel[TM], is presented. The model is based on the random selection of cells in an array. The results compare well with the theoretical equations. The model is a useful tool in teaching this aspect of radioactivity. (Contains 4 figures.)

  1. Magnetic resonance imaging of trilucent TM breast implants

    International Nuclear Information System (INIS)

    AIM: To demonstrate the magnetic resonance imaging (MRI) appearances of intact and ruptured Trilucent TM implants with imaging and surgical correlation. The appearances of the implant transponder artefact are also described MATERIALS AND METHODS: A retrospective review of the MRI findings in 34 patients with bilateral subpectoral Trilucent TM breast implants (Lipomatrix, Inc./Collagen Aesthetics International Inc., Neuchatel, Switzerland) was performed. Patients under implant surveillance and those with suspected implant rupture formed the study group. Imaging findings were correlated with surgical appearances. RESULTS: Surgical correlation was available in 53% of patients. Fifty per cent (18/36) of implants were intact at surgery, 50% (18/36) of implants were ruptured. Of the 18 ruptured implants, 17 were intracapsular ruptures and one an extracapsular rupture. The sensitivity of MRI for detection of intracapsular rupture in Trilucent TM breast implants was 82% specificity 76%, positive predictive value 78%, negative predictive value 81% and accuracy 79% in this study group. No case of implant rupture was obscured by the transponder artefact. Four implants were found to have 'pseudocapsules' at surgery (5·9%), the implants were intact with fluid present between the implant and capsule. Only one pseudocapsule was demonstrated on MRI. CONCLUSION: Magnetic resonance imaging is currently the most accurate technique for diagnosis of implant rupture in Trilucent TM breast implants. Transponder artefact does not appear to interfere with the assessment of implant rupture. Elson, E. M. et al. (2002)

  2. CPR[TM]: Adopting an Out-of-Discipline Innovation

    Science.gov (United States)

    Strong, Kay E.

    2008-01-01

    Calibrated Peer Review[TM] (CPR) is a web-based instructional tool that encourages "writing gain for students" without adding "grading pain for the instructor!" The use of CPR provides students frequent opportunities to hone both writing as well as peer review skills in a guided environment. And once an assignment is authored, instructors have…

  3. Error detection and reduction within DriftLessTM

    NARCIS (Netherlands)

    Hall, E.W. van der

    2013-01-01

    This thesis presents an algorithm that can reduce the estimation errors made with the DriftLessTM bias estimation technique. The algorithm utilizes the autocorrelation function to detect the presence of errors, and a minimization function to reduce these errors. The algorithm has been validated with

  4. Buff Thermo°CoolTM Team On Top

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Andalusia 13-14 March:The Thermo°CoolTM sponsored Extreme Raid team celebrated their triumph over the fourth edition of the Adventure Raid Sierras Subbeticas.The team finished at 1st position after an exhausting race and a tough fighting against time and altitudes of above 1300 meters.Team members

  5. Herman Method[TM]. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2010

    2010-01-01

    The "Herman Method"[TM] teaches reading in small groups of up to three students. The curriculum provides instruction in phonemic awareness, phonics, fluency, vocabulary, and reading comprehension, while also teaching spelling and writing. It contains 20 modules of instruction through a fifth grade level. Each module includes a reading, spelling,…

  6. Tilted axis rotation in odd-odd {sup 164}Tm

    Energy Technology Data Exchange (ETDEWEB)

    Reviol, W.; Riedinger, L.L.; Wang, X.Z.; Zhang, J.Y. [Univ. of Tennessee, Knoxville, TN (United States)] [and others

    1996-12-31

    Ten band structures are observed in {sup 164}Tm, among them sets of parallel and anti-parallel couplings of the proton and neutron spins. The Tilted Axis Cranking scheme is applied for the first time to an odd-odd nucleus in a prominent region of nuclear deformation.

  7. Transmission Measurement and Resonance Parameter Determination of 169Tm

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>The transmission rate of 169Tm, ranging from 0.01 to 100 eV, were measured with n-TOF method at the Pohang Neutron Facility (PNF), which consists of an electron linac, a water-cooled Ta target, and a 12

  8. Evaluation of NGAL TestTM on Cobas 6000

    DEFF Research Database (Denmark)

    Hansen, Young B L; Damgaard, Anette; Poulsen, Jørgen H

    2014-01-01

    BACKGROUND: Neutrophil Gelatinase-Associated Lipocalin (NGAL) is a promising biomarker for acute kidney injury (AKI). Our objectives were to evaluate the NGAL Test(TM) from Bioporto for both urine NGAL and plasma NGAL on the Cobas 6000 c501 (Roche Diagnostics, Rotkreuz, Switzerland) with matched ...

  9. Forest Attributes Estimation Using Aerial Laser Scanner and TM Data

    Directory of Open Access Journals (Sweden)

    S. Shataee Joibary

    2013-12-01

    Full Text Available Aim of study: The aim of this study was performance of four non-parametric algorithms including the k-NN, SVR, RF and ANN to estimate forest volume and basal area attributes using combination of Aerial Laser Scanner and Landsat-TM data.Area of study: Data in small part of a mixed managed forest in the Waldkirch region, Germany.Material and methods: The volume/ha and basal area/ha in the 411 circular plots were estimated based on DBH and height of trees using volume functions of study area. The low density ALS raw data as first and last pulses were prepared and automatically classified into vegetation and ground returns to generate two fine resolution digital terrain and surface models after noise removing. Plot-based height and density metrics were extracted from ALS data and used both separated and combined with orthorectified and processed TM bands. The algorithms implemented with different options including k-NN with different distance measures, SVR with the best regularized parameters for four kernel types, RF with regularized decision tree parameters and ANN with different types of networks. The algorithm performances were validated using computing absolute and percentage RMSe and bias on unused test samples.Main results: Results showed that among four methods, SVR using the RBF kernel could better estimate volume/ha with lower RMSe and bias (156.02 m3 ha–1 and 0.48, respectively compared to others. In basal area/ha, k-NN could generate results with similar RMSe (11.79 m3 ha–1 but unbiased (0.03 compared to SVR with RMSe of 11.55 m3 ha–1 but slightly biased (–1.04.Research highlights: Results exposed that combining Lidar with TM data could improve estimations compared to using only Lidar or TM data.Key words: forest attributes estimation; ALS; TM; non-parametric algorithms.

  10. Tri-Decadal Global Landsat Orthorectified TM Mosaics: 1984-1997

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Landsat TM Orthorectified Mosaics data collection is derived from a global set of high-quality, relatively cloud-free orthorectified TM imagery from Landsats...

  11. User prototypes as partly unconscious communication

    DEFF Research Database (Denmark)

    Glasemann, Marie; Kanstrup, Anne Marie

    2010-01-01

    In this paper, we introduce user prototypes as a technique that supports users’ articulation of emotions relevant for design: dreams, fears, motivations – their feelings and aspirations. Following Bateson’s writings about communication through art, we consider user prototypes as “partly unconscious...... communication” and propose to analyze them by focusing on the emotional articulations integrated in the users’ design language. We illustrate this with an example from a design research project on designing learning technology for young diabetics. The example shows how young people with diabetes can express...... emotional themes related to youth identity, the burden of being young with a chronic illness, and the need to be connected and feel safe through design of prototypes. The new conceptual space that arises from user prototypes shows potential for addressing emotions when designing for health and for further...

  12. Prototype solar-heating system - installation manual

    Science.gov (United States)

    1978-01-01

    Manual for prototype solar-heating system gives detailed installation procedures for each of seven subsystems. Procedures for operation and maintenance are also included. It discusses architectural considerations, building construction considerations, and checkout-test procedures.

  13. Presentation Trainer Prototype 1.0

    NARCIS (Netherlands)

    Börner, Dirk; Specht, Marcus

    2014-01-01

    This software sketch comprises the first prototype of the presentation trainer. The application uses the Microsoft Kinect sensor and was built using the Processing 1.5.1 development environment. Available under the GNU LGPL licence version 3 or higher.

  14. Power test for first prototype LIBO module

    CERN Multimedia

    Laurent Guiraud

    2000-01-01

    The Linac Booster (LIBO) is a prototype machine for producing particle beams for cancer therapy. Hadron therapy techniques are able to reach deep tumours with less damage to surrounding tissue than with conventional radiotherapy.

  15. Prototypes, Genres, and Concepts: Travelling with Narratives

    Directory of Open Access Journals (Sweden)

    Matti Hyvärinen

    2012-11-01

    Full Text Available The “narrative turn” is (too often understood as a celebratory term indicating the growing importance and popularity of narrative studies. This article elaborates the merits of a more critical approach to the history of narrative theory. By discussing David Herman’s idea of prototypical narrativity, the article suggests that there has been a longstanding contradiction between the abstract and universal notion of narrative and the narrow and particular Proppian prototype of narrativity. The article argues that “narrative” has primarily travelled either as a concept, metaphor, or prototype rather than as a full narrative theory or method. Instead of one, unitary narrative turn, the article argues for the existence of several diverse and partly contrasting narrative turns. The recent experiential turn in narrative studies and the consequent change of the prototype of narrative gives a strong impetus for a new wave of cross-disciplinary narrative theory.

  16. Gesture Recognition for an Exergame Prototype

    OpenAIRE

    Gacem, Brahim; Vergouw, Robert; Verbiest, Harm; Cicek, Emrullah; Van Oosterhout, Tim; Bakkes, Sander; Kröse, Ben

    2011-01-01

    We will demonstrate a prototype exergame aimed at the serious domain of elderly fitness. The exergame incorporates straightforward means to gesture recognition, and utilises a Kinect camera to obtain 2.5D sensory data of the human user.

  17. Homogeneity of Prototypical Attributes in Soccer Teams

    Directory of Open Access Journals (Sweden)

    Christian Zepp

    2015-09-01

    Full Text Available Research indicates that the homogeneous perception of prototypical attributes influences several intragroup processes. The aim of the present study was to describe the homogeneous perception of the prototype and to identify specific prototypical subcategories, which are perceived as homogeneous within sport teams. The sample consists of N = 20 soccer teams with a total of N = 278 athletes (age M = 23.5 years, SD = 5.0 years. The results reveal that subcategories describing the cohesiveness of the team and motivational attributes are mentioned homogeneously within sport teams. In addition, gender, identification, team size, and the championship ranking significantly correlate with the homogeneous perception of prototypical attributes. The results are discussed on the basis of theoretical and practical implications.

  18. The BeUpstanding ProgramTM: Scaling up the Stand Up Australia Workplace Intervention for Translation into Practice

    Directory of Open Access Journals (Sweden)

    Genevieve N Healy

    2016-05-01

    Full Text Available Context and purpose: Too much sitting is now recognised as a common risk factor for several health outcomes, with the workplace identified as a key setting in which to address prolonged sitting time. The Stand Up Australia intervention was designed to reduce prolonged sitting in the workplace by addressing influences at multiple-levels, including the organisation, the environment, and the individual. Intervention success has been achieved within the context of randomised controlled trials, where research staff deliver several of the key intervention components. This study describes the initial step in the multi-phase process of scaling up the Stand Up Australia intervention for workplace translation. Methods: A research-government partnership was critical in funding and informing the prototype for the scaled up BeUpstanding programTM. Evidence, protocols and materials from Stand Up Australia were adapted in collaboration with funding partner Workplace Health and Safety Queensland to ensure consistency and compatibility with existing government frameworks and resources. In recognition of the key role of workplace champions in facilitating workplace health promotion programs, the BeUpstanding programTM is designed to be delivered through a stand-alone, free, website-based toolkit using a 'train the champion' approach. Key findings and significance: The BeUpstanding programTM was influenced by the increasing recognition of prolonged sitting as an emerging health issue as well as industry demand. The research-government partnership was critical in informing and resourcing the development of the scaled-up program.

  19. Sealing ability of grar MTA AngelusTM, CPM TM and MBPc used as apical plugs.

    Science.gov (United States)

    Orosco, Fernando Accorsi; Bramante, Clovis Monteiro; Garcia, Roberto Brandão; Bernadineli, Norberti; Moraes, Ivaldo Gomes de

    2008-01-01

    This study evaluated the sealing ability of apical plugs fabricated with gray MTA Angelus sealer, CPM TM sealer and MBPc sealer. The root canals of 98 extracted single-rooted human teeth were instrumented with #5 to #1 Gates Glidden drills according to the crown-down technique until the #1 drill could pass through the apical foramen. The specimens were then prepared with K-files, starting with an ISO 50 until an ISO 90 could be visualized 1 mm beyond the apex. After root canal preparation, the external surface of each root was rendered impermeable and roots were assigned to 3 experimental groups (n = 30), which received a 5-mm thick apical plug of gray MTA Angelus, CPM and MBPc, and two control groups (n=4). The remaining portion of the canal in the experimental groups was filled by the lateral condensation technique. The teeth of each group, properly identified, were fixed on utility wax by their crowns and were placed in plastic flasks, leaving the apex free and facing upward. The flasks were filled with 0.2% Rhodamine B solution, pH 7.0, so as to completely cover the root apex of all teeth. The sealing ability was analyzed by measuring 0.2% Rhodamine B leakage after all groups had been maintained in this solution for 48 hours. Data were analyzed statistically by Kruskal-Wallis test and Dunn test with a=5%. The results showed that, among the tested materials used for fabrication of apical plugs, MBPc sealer had the least amount of leakage with statistically significant difference (p<0.05). PMID:19089289

  20. MPACT Fast Neutron Multiplicity System Prototype Development

    Energy Technology Data Exchange (ETDEWEB)

    D.L. Chichester; S.A. Pozzi; J.L. Dolan; M.T. Kinlaw; S.J. Thompson; A.C. Kaplan; M. Flaska; A. Enqvist; J.T. Johnson; S.M. Watson

    2013-09-01

    This document serves as both an FY2103 End-of-Year and End-of-Project report on efforts that resulted in the design of a prototype fast neutron multiplicity counter leveraged upon the findings of previous project efforts. The prototype design includes 32 liquid scintillator detectors with cubic volumes 7.62 cm in dimension configured into 4 stacked rings of 8 detectors. Detector signal collection for the system is handled with a pair of Struck Innovative Systeme 16-channel digitizers controlled by in-house developed software with built-in multiplicity analysis algorithms. Initial testing and familiarization of the currently obtained prototype components is underway, however full prototype construction is required for further optimization. Monte Carlo models of the prototype system were performed to estimate die-away and efficiency values. Analysis of these models resulted in the development of a software package capable of determining the effects of nearest-neighbor rejection methods for elimination of detector cross talk. A parameter study was performed using previously developed analytical methods for the estimation of assay mass variance for use as a figure-of-merit for system performance. A software package was developed to automate these calculations and ensure accuracy. The results of the parameter study show that the prototype fast neutron multiplicity counter design is very nearly optimized under the restraints of the parameter space.

  1. An Application of Chromatic Prototypes for a Universal Information System

    CERN Document Server

    McCool, Matthew

    2007-01-01

    This paper presents research on color prototypes, categories, and the neuropsychology of color. These data suggest that chromatic prototypes may be useful for thematically organizing information systems.

  2. Coupling between magnetic and optical properties of GaN:TM (TM: V, Cr, Mn, Fe, Co, Ni): First-principle study with LDA-SIC approximation

    Science.gov (United States)

    Salmani, El mehdi; Mounkachi, Omar; Ez-Zahraouy, Hamid; Benyoussef, Abdelilah; Hamedoun, Mohammed; Hlil, El kebir

    2013-11-01

    Electronic structure, magnetic and optical properties of GaN:TM (TM: V, Cr, Mn, Fe, Co, Ni), based dilute magnetic semiconductors (DMS), are investigated using first-principles calculations. The energy difference between the ferromagnetic and disorder local moment states has been evaluated. Moreover, the optical absorption spectra obtained by ab-initio calculations confirm the ferromagnetic stability based on the charge state of magnetic impurities. Our results show that the ferromagnetic state is stable when TM introduce simultaneously magnetic moment and intrinsic carriers in (Ga, TM)N. Some studied ferromagnetic DMS exhibit half-metallic behavior, which is suitable for spintronics applications.

  3. Very high coupling of TM polarised light in photonic crystal directional couplers

    DEFF Research Database (Denmark)

    Borel, Peter Ingo; Thorhauge, Morten; Frandsen, Lars Hagedorn;

    2003-01-01

    The experimental and simulated spectra for TE and TM polarised light for the transmission through photonic crystal directional couplers are presented. The 3D FDTD simulations successfully explain all the major features of the experimental spectra as well as the actual transmission level. Especially...... noteworthy is the transmission level, experimentally found to be above -3 dB in the wavelength range 1520-1690 nm, for TM polarised light in the coupled channel. It is noted that even though band calculations show that the propagation of the TM polarisation takes place below the TM valence band, very high...... and spectrally smooth coupling is observed for the TM polarisation in this wavelength range....

  4. ALDUO(TM) Algae Cultivation Technology for Delivering Sustainable Omega-3s, Feed, and Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Bai, Xuemei [Cellana LLC

    2012-09-24

    * ALDUO(TM) Algae Production Technology Cellana?s Proprietary, Photosynthetic, & Proven * ALDUO(TM) Enables Economic Algae Production Unencumbered by Contamination by Balancing Higher-Cost PBRs with Lower-Cost Open Ponds * ALDUO(TM) Advantages * ALDUO(TM) Today o Large collection of strains for high value co-products o Powerful Mid-scale Screening & Optimization System o Solution to a Conflicting Interest o Split Pond Yield Enhancement o Heterotrophy & mixotrophy as a "finishing step" o CO2 Mitigation-flue Gas Operation o Worldwide Feed Trials with Livestock & Aquatic Species * ALDUO(TM) Technology Summarized

  5. 102 W monolithic single frequency Tm-doped fiber MOPA.

    Science.gov (United States)

    Wang, Xiong; Zhou, Pu; Wang, Xiaolin; Xiao, Hu; Si, Lei

    2013-12-30

    We demonstrate a high power all-fiber single frequency Tm-doped fiber amplifier. The maximum output power reached 102 W and the central wavelength was 1.97 μm. The single frequency laser signal from a seed laser was amplified based on a monolithic master oscillator power amplifier (MOPA) configuration. The slope efficiency was about 50% against the absorbed pump power. Neither parasitic lasing nor nonlinear effect was observed in the monolithic fiber amplifier. The SBS threshold of the single frequency Tm-doped fiber amplifier was analyzed and estimated. The output power is not limited by the SBS threshold and could be further improved by increasing the pump power. To the best of our knowledge, this is the first demonstration of average power exceeding 100 W from monolithic all-fiber laser near 2 μm wavelength. PMID:24514831

  6. AmlamaxTM in the management of dyslipidemia in humans

    Directory of Open Access Journals (Sweden)

    Antony B

    2008-01-01

    Full Text Available Hypercholesterolemia is the major cause of cardiovascular diseases leading to myocardial infarctions leading to considerable morbidity and mortality. During the past decade a group of molecules referred to as statins such as simvastatin, atrovastatin have been tried with great success in reducing total cholesterol. These molecules act by inhibiting the HMG CoA reductase enzyme thereby interfering with the synthesis of cholesterol. But statins reduce all the cholesterol including HDL cholesterol. Long term drug vigilance activity has revealed serious side effects of tendinopathy and related musculoskeletal disorders in some of the subjects. In an effort to manage hypercholesterolemia without serious side effects in a natural way we had tried the use of Amlamax TM a reconstituted, purified, standardized dried extract of amla ( Emblica officinalis containing 30% ellagitannins with other hydrolysable tannins on humans. We report the hitherto unobserved significant elevation of HDL cholesterol by the administration of Amlamax TM

  7. Close encounters of the prototype kind

    CERN Multimedia

    2005-01-01

    CERN is building a new control centre for the operation of its entire accelerator complex and technical infrastructure. The prototype console for the new centre has just been installed and tested. Close encounters of the prototype kind CERN is building a new control centre for the operation of its entire accelerator complex and technical infrastructure. The prototype console for the new centre has just been installed and tested. The prototype of the control consoles that will be at the heart of the future CERN Control Centre (CCC) has just been installed in the Roy Billinge Room in Building 354. Until now, there have been four separate control rooms for the CERN accelerators and technical infrastructure. The CCC, which will be located on the Prévessin site, will bring them all together in a single room. The Centre will consist of 40 consoles for four different areas (LHC, SPS, PS complex and technical infrastructure). The prototype was tested by the technicians for a month. Following installation and con...

  8. The energy performance of prototype holographic glazings

    Science.gov (United States)

    Papamichael, K.; Beltran, L.; Furler, R.; Lee, E. S.; Selkowitz, S.; Rubin, M.

    1993-02-01

    We report on the simulation of the energy performance of prototype holographic glazings in commercial office buildings in a California climate. These prototype glazings, installed above conventional side windows, are designed to diffract the transmitted solar radiation and reflect it off the ceiling, providing adequate daylight illumination for typical office tasks up to 10m from the window. In this study, we experimentally determined a comprehensive set of solar-optical properties and characterized the contribution of the prototype holographic glazings to workplane illuminance in a scale model of a typical office space. We then used the scale model measurements to simulate the energy performance of the holographic glazings over the course of an entire year for four window orientations (North, East, South and West) for the inland Los Angeles climate, using the DOE-2.lD building energy analysis computer program. The results of our experimental analyses indicate that these prototype holographic glazings diffract only a small fraction of the incident light. The results of this study indicate that these prototype holographic glazings will not save energy in commercial office buildings. Their performance is very similar to that of clear glass, which, through side windows, cannot efficiently illuminate more than a 4-6 m depth of a building's perimeter, because the cooling penalties due to solar heat gain are greater than the electric lighting savings due to daylighting.

  9. Prototype for Extended XDB Using Wiki

    Directory of Open Access Journals (Sweden)

    Wook-Sung Yoo

    2012-11-01

    Full Text Available This paper describes a prototype of extended XDB. XDB is an open-source and extensible database architecture developed by National Aeronautics and Space Administration (NASA to provide integration of heterogeneous and distributed information resources for scientific and engineering applications. XDB enables an unlimited number of desktops and distributed information sources to be linked seamlessly and efficiently into an information grid using Data Access and Retrieval Composition (DARC protocol whichprovides a contextual search and retrieval capability useful for lightweight web applications. This paper shows the usage of XDB on common data management in the enterprise without burdening users and application developers with unnecessary complexity and formal schemas. Supported by NASA Ames Research Center through NASA Exploration System Mission Directorate (ESMD Higher Education grant, a project team at Fairfield University extended this concept and developed an extended XDB protocol and a prototype providing text-searches for Wiki. The technical specification of the protocol was posted to Source Forge (sourceforge.net and a prototype providing text-searches for Wiki was developed. The prototype was created for 16 tags of the MediaWiki dialect. As part of future works, the prototype will be further extended to the complete Wiki markups and other dialects of Wiki.

  10. Visualizing and Presenting Story Maps in TM4Book

    OpenAIRE

    Johnsen, Lars; Dichev, Christo; Dicheva, Darina

    2011-01-01

    This short paper focuses on the visualization and presentation of storylines and suchlike narrative information in TM4Book, a Topic Maps-based semantic annotation tool for creative writing and textual analysis. Drawing on common gestalt principles as well as notions from semiotics and current discourse theory, the paper proposes some general strategies for displaying visual “story maps” and making them interactive for the user.

  11. High resolution imaging with TM01 laser beams

    Science.gov (United States)

    Dehez, Harold; Piché, Michel; De Koninck, Yves

    2009-06-01

    Using the vectorial diffraction theory established by Richards and Wolf, we demonstrate that the resolution of a two-photon microscope can be improved with a radially polarized TM01 laser beam and an interface between dielectrics, instead of the linearly polarized Gaussian beam already used in laser scanning microscopy. To verify the theoretical results, we developed a mode converter producing radially polarized beams and we have integrated it in a commercial two-photon microscope.

  12. Intubation with Airtraq TM laryngoscope in a morbidly obese patient

    OpenAIRE

    Pratik Tantia; Sunny Malik; Shahin Jamil; Rajiv Samal

    2011-01-01

    In the present study, we report a case of successful endotracheal intubation using Airtraq TM Laryngoscope (AQL) in a morbidly obese patient. A 35-year-old woman, morbidly obese (weight, 105 kg; height, 160 cm; BMI, 41 kg/m 2 ), known hypertensive and diabetic, was admitted in the operating room for total abdominal hysterectomy under general anesthesia. The preoperative airway assessment anticipated both difficult bag-mask ventilation and intubation. Tracheal intubation using AQL was attempte...

  13. Experiences with OpenMP in tmLQCD

    Energy Technology Data Exchange (ETDEWEB)

    Deuzeman, A. [Bern Univ. (Switzerland). Albert Einstein Center for Fundamental Physics; Jansen, K. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Kostrzewa, B. [Humboldt Univ. Berlin (Germany). Inst. fuer Physik; Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Urbach, C. [Bonn Univ. (Germany). HISKP (Theory); Collaboration: European Twisted Mass Collaboration

    2013-11-15

    An overview is given of the lessons learned from the introduction of multi-threading using OpenMP in tmLQCD. In particular, programming style, performance measurements, cache misses, scaling, thread distribution for hybrid codes, race conditions, the overlapping of communication and computation and the measurement and reduction of certain overheads are discussed. Performance measurements and sampling profiles are given for different implementations of the hopping matrix computational kernel.

  14. Structure and properties of TM processed HSLA steels

    OpenAIRE

    Kneissl, A.; Baldinger, P

    1993-01-01

    This paper deals with the influence of steel composition (with respect to the microalloying elements) and thermomechanical treatment on structure and mechanical behaviour of HSLA (High Strength Low Alloy) steels. Four different microalloyed steels have been TM rolled under variing conditions. The austenite structure prior to transformation could be revealed by means of a special etching technique. The precipitation behaviour has been studied by TEM, STEM and APFIM investigations. The results ...

  15. Efficient Tm$^{3+}$ lasers in double tungstate channel waveguides

    NARCIS (Netherlands)

    Dalfsen, van K.; Aravazhi, S.; Geskus, D.; Wörhoff, K.; Pollnau, M.

    2011-01-01

    Gd3+(29.5%)-Lu3+(29.0%)-Tm3+(1.5%) co-doped KY(WO4)2 layers were grown onto KY(WO4)2 substrates by liquid-phase epitaxy and microstructured by Ar+-beam milling. Laser experiments with butt-coupled dielectric mirrors demonstrated maximum output powers of 149 mW and slope efficiencies of 31.5% when pu

  16. Forest attributes estimation using aerial laser scanner and TM data

    Energy Technology Data Exchange (ETDEWEB)

    Shataee, S.

    2013-07-01

    Aim of study: The aim of this study was performance of four non-parametric algorithms including the k-NN, SVR, RF and ANN to estimate forest volume and basal area attributes using combination of Aerial Laser Scanner and Landsat- TM data. Area of study: Data in small part of a mixed managed forest in the Waldkirch region, Germany. Material and methods: The volume/ha and basal area/ha in the 411 circular plots were estimated based on DBH and height of trees using volume functions of study area. The low density ALS raw data as first and last pulses were prepared and automatically classified into vegetation and ground returns to generate two fine resolution digital terrain and surface models after noise removing. Plot-based height and density metrics were extracted from ALS data and used both separated and combined with orthorectified and processed TM bands. The algorithms implemented with different options including k-NN with different distance measures, SVR with the best regularized parameters for four kernel types, RF with regularized decision tree parameters and ANN with different types of networks. The algorithm performances were validated using computing absolute and percentage RMSe and bias on unused test samples. Main results: Results showed that among four methods, SVR using the RBF kernel could better estimate volume/ha with lower RMSe and bias (156.02 m{sup 3} ha{sup -}1 and 0.48, respectively) compared to others. In basal area/ha, k-NN could generate results with similar RMSe (11.79 m{sup 3} ha{sup -}1) but unbiased (0.03) compared to SVR with RMSe of 11.55 m{sup 3} ha{sup -}1 but slightly biased (-1.04). Research highlights: Results exposed that combining Lidar with TM data could improve estimations compared to using only Lidar or TM data. (Author)

  17. Augmenting Forest Stand Parameters using Landsat TM Spectral Images

    Science.gov (United States)

    Reuveni, Y.; Dahan, E.; Anker, Y.; Sprintsin, M.

    2015-12-01

    Forest stand parameters, such as diameter at breast height (DBH), tree height (H), or volume per hectare (V), are imperative for forest resources assessment. Traditional inventory of forest stand parameters, usually based on fieldwork, is often difficult, time-consuming, and expensive, to conduct in large areas. Therefore, estimating forest stand parameters in large areas using traditional inventory approach augmented by satellites data has a significant implication for sustainable forest management and natural resources efficiency. However, obtaining suitable satellite image data for such purpose is a challenging task mainly because of insignificant knowledge between the forest stand parameters and satellite spectral response relationships. Here, we present the use of Landsat Thematic Mapper (TM) spectral responses data for augmenting forest stand parameter obtained from fieldwork at the Lahav Forest, in the Israeli Northern Negev. A new algorithm was developed in order to use all eight TM band when calculating the linear combination which correlates the most to each one of the forest stand parameters. Each linear combination is obtained first for local area inside the entire studied grid and is then fitted using a simple linear polynomial curve to the known forest stand parameter. Once the relationship between the two is characterized by a linear polynomial equation, the TM linear combination local area data is translated to the same equivalent area of the chosen forest stand parameter. At last, we interpolate the entire TM grid using a higher order polynomial fit applied to all the augmented local area combined together to attain full coverage of the desired forest stand parameter.

  18. Mass balance investigation of alpine glaciers through LANDSAT TM data

    Science.gov (United States)

    Bayr, Klaus J.

    1989-01-01

    An analysis of LANDSAT Thematic Mapper (TM) data of the Pasterze Glacier and the Kleines Fleisskees in the Austrian Alps was undertaken and compared with meteorological data of nearby weather stations. Alpine or valley glaciers can be used to study regional and worldwide climate changes. Alpine glaciers respond relatively fast to a warming or cooling trend in temperature through an advance or a retreat of the terminus. In addition, the mass balance of the glacier is being affected. Last year two TM scenes of the Pasterze Glacier of Aug. 1984 and Aug. 1986 were used to study the difference in reflectance. This year, in addition to the scenes from last year, one MSS scene of Aug. 1976 and a TM scene from 1988 were examined for both the Pasterze Glacier and the Kleines Fleisskees. During the overpass of the LANDSAT on 6 Aug. 1988 ground truthing on the Pasterze Glacier was undertaken. The results indicate that there was considerable more reflectance in 1976 and 1984 than in 1986 and 1988. The climatological data of the weather stations Sonnblick and Rudolfshuette were examined and compared with the results found through the LANDSAT data. There were relations between the meteorological and LANDSAT data: the average temperature over the last 100 years showed an increase of .4 C, the snowfall was declining during the same time period but the overall precipitation did not reveal any significant change over the same period. With the use of an interactive image analysis computer, the LANDSAT scenes were studied. The terminus of the Pasterze Glacier retreated 348 m and the terminus of the Kleines Fleisskees 121 m since 1965. This approach using LANDSAT MSS and TM digital data in conjunction with meteorological data can be effectively used to monitor regional and worldwide climate changes.

  19. CHROMITITE PROSPECTING USING LANDSAT TM AND ASTER REMOTE SENSING DATA

    Directory of Open Access Journals (Sweden)

    A. Beiranvand Pour

    2015-10-01

    Full Text Available Studying the ophiolite complexes using multispectral remote sensing satellite data are interesting because of high diversity of minerals and the source of podiform chromitites. This research developed an approach to discriminate lithological units and detecting host rock of chromitite bodies within ophiolitic complexes using the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER and Landsat Thematic Mapper (TM satellite data. Three main ophiolite complexes located in south of Iran have been selected for the study. Spectral transform techniques, including minimum noise fraction (MNF and specialized band ratio were employed to detect different rock units and the identification of high-potential areas of chromite ore deposits within ophiolitic complexes. A specialized band ratio (4/1, 4/5, 4/7 of ASTER, MNF components and Spectral Angle Mapper (SAM on ASTER and Landsat TM data were used to distinguish ophiolitic rock units. Results show that the specialized band ratio was able to identify different rock units and serpentinized dunite as host rock of chromitites within ophiolitic complexes, appropriately. MNF components of ASTER and Landsat TM data were suitable to distinguish ophiolitic rock complexes at a regional scale. The integration of SAM and Feature Level Fusion (FLF used in this investigation discriminated the ophiolitic rock units and prepared detailed geological map for the study area. Accordingly, high potential areas (serpentinite dunite were identified in the study area for chromite exploration targets.The approach used in this research offers the image processing techniques as a robust, reliable, fast and cost-effective method for detecting serpentinized dunite as host rock of chromitite bodies within vast ophiolite complexes using ASTER and Landsat TM satellite data.

  20. Tm2+ luminescent materials for solar radiation conversion devices

    OpenAIRE

    Van der Kolk, E.

    2015-01-01

    A solar radiation conversion device is described that comprises a luminescent Tm 2+ inorganic material for converting solar radiation of at least part of the UV and/or visible and/or infra red solar spectrum into infrared solar radiation, preferably said infrared solar radiation having a wavelength of around 1138 nm; and, a photovoltaic device for converting at least part of said infrared solar radiation into electrical power.

  1. Magnetic Structure of Tb-Tm Alloys Studied by Neutron Diffraction

    DEFF Research Database (Denmark)

    Hansen, P.; Lebech, Bente

    1976-01-01

    Single crystals of Tb-Tm alloys with Tm contents of 12%, 40%, 55% and 65% were investigated by neutron diffractometry over the temperature range 4.2-300K. All these alloys order magnetically to a basal plane spiral below the Neel temperature. Below the Curie temperature the magnetic ordering of the...... Tb-12% Tm alloy is ferromagnetic with the moments in the basal plane, while the other alloys have a ferromagnetic component along the c axis and a spiral component in the basal plane below Tc. The Tb-55%Tm and the Tb-65%Tm alloys have an intermediate mixed phase, where the c axis component is...... modulated along the c axis (CAM structure). Tb-Tm alloys have an inhomogeneous phase, where the spins associated with the Tb ions lie in the basal plane, while the spins associated with the Tm ions order along the c axis....

  2. Performance of the SDHCAL technological prototype

    CERN Document Server

    Grenier, Gérald

    2016-01-01

    The SDHCAL technological prototype is a $1 \\times 1 \\times 1.3$~m$^3$ high-granularity Semi-Digital Hadronic CALorimeter using Glass Resistive Plate Chambers as sensitive medium. It is one of the two HCAL options considered by the ILD Collaboration to be proposed for the detector of the future International Linear Collider project. The prototype is made of up to 50 GRPC detectors of 1~m$^2$ size and 3~mm thickness each with an embedded semi-digital electronics readout that is autotriggering and power-pulsed. The GRPC readout is finely segmented into pads of 1~cm$^2$. This proceeding describes the prototype, its operation and its performance in energy reconstruction. Aspects of the GRPC readout modelling and comparisons with simulations are also presented.

  3. Performance studies of MRPC prototypes for CBM

    CERN Document Server

    Deppner, I; Frühauf, J; Kiš, M; Lyu, P; Loizeau, P -A; Shi, L; Simon, C; Wang, Y; Xie, B

    2016-01-01

    Multi-gap Resistive Plate Chambers (MRPCs) with multi-strip readout are considered to be the optimal detector candidate for the Time-of-Flight (ToF) wall in the Compressed Baryonic Matter (CBM) experiment. In the R&D phase MRPCs with different granularities, low-resistive materials and high voltage stack configurations were developed and tested. Here, we focus on two prototypes called HD-P2 and THU-strip, both with strips of 27 cm$^2$ length and low-resistive glass electrodes. The HD-P2 prototype has a single-stack configuration with 8 gaps while the THU-strip prototype is constructed in a double-stack configuration with 2 $\\times$ 4 gaps. The performance results of these counters in terms of efficiency and time resolution carried out in a test beam time with heavy-ion beam at GSI in 2014 are presented in this proceeding.

  4. Preliminary test results of LAr prototype detector

    CERN Document Server

    Li, Pei-Xian; Yang, Chang-Gen; Zhang, Peng; Liu, Jin-Chang; Zhang, Yong-Pen; Guo, Cong; Wang, Yi

    2016-01-01

    WIMPs are a well-motivated galactic dark matter candidate. Liquid argon (LAr) is an attractive target for the direct detection of WIMPs. The LAr prototype detector is designed to study the technology and property of LAr detector. The prototype detector have an active volume containing 0.65 kg of liquid argon. The liquid nitrogen(LN) cooling system allows the temperature of liquid argon to be maintained at the boiling point (87.8 K) with fluctuations less than 0.1 K. The prototype was calibrated with a Na$^{22}$ source, with the light yield 1.591$\\pm$0.019 p.e./keV for the 511 keV gamma rays using the domestic-made argon purification system.

  5. A COMPUTERIZED OPERATOR SUPPORT SYSTEM PROTOTYPE

    Energy Technology Data Exchange (ETDEWEB)

    Thomas A. Ulrich; Roger Lew; Ronald L. Boring; Ken Thomas

    2015-03-01

    A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. A prototype COSS was developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based on four underlying elements consisting of a digital alarm system, computer-based procedures, piping and instrumentation diagram system representations, and a recommender module for mitigation actions. The initial version of the prototype is now operational at the Idaho National Laboratory using the Human System Simulation Laboratory.

  6. Prototype Hanford Surface Barrier: Design basis document

    International Nuclear Information System (INIS)

    The Hanford Site Surface Barrier Development Program (BDP) was organized in 1985 to develop the technology needed to provide a long-term surface barrier capability for the Hanford Site and other arid sites. This document provides the basis of the prototype barrier. Engineers and scientists have momentarily frozen evolving barrier designs and incorporated the latest findings from BDP tasks. The design and construction of the prototype barrier has required that all of the various components of the barrier be brought together into an integrated system. This integration is particularly important because some of the components of the protective barreir have been developed independently of other barreir components. This document serves as the baseline by which future modifications or other barrier designs can be compared. Also, this document contains the minutes of meeting convened during the definitive design process in which critical decisions affecting the prototype barrier's design were made and the construction drawings

  7. HSI Prototypes for Human Systems Simulation Laboratory

    International Nuclear Information System (INIS)

    This report describes in detail the design and features of three Human System Interface (HSI) prototypes developed by the Institutt for Energiteknikk (IFE) in support of the U.S. Department of Energy's Light Water Reactor Sustainability Program under Contract 128420 through Idaho National Laboratory (INL). The prototypes are implemented for the Generic Pressurized Water Reactor simulator and installed in the Human Systems Simulation Laboratory at INL. The three prototypes are: 1) Power Ramp display 2) RCS Heat-up and Cool-down display 3) Estimated time to limit display The power ramp display and the RCS heat-up/cool-down display are designed to provide good visual indications to the operators on how well they are performing their task compared to their target ramp/heat-up/cool-down rate. The estimated time to limit display is designed to help operators restore levels or pressures before automatic or required manual actions are activated.

  8. Ceramic microfabrication by rapid prototyping process chains

    Indian Academy of Sciences (India)

    R Knitter; W Bauer

    2003-02-01

    Fabrication of micropatterned ceramics or ceramic microparts make high demands on the precision and resolution of the moulding process. As finishing of miniaturised or micropatterned ceramic components is nearly impossible, shaping has to be done by a replication step in the green, unfired state. To avoid high tooling costs in product development, a rapid prototyping process chain has been established that enables rapid manufacturing of ceramic microcomponents from functional models to small lot series within a short time. This process chain combines the fast and inexpensive supply of master models by rapid prototyping with accurate and flexible ceramic manufacturing by low-pressure injection moulding. Besides proper feedstock preparation and sufficient small grain size, the quality of the final components is mainly influenced by the quality of the master model. Hence, the rapid prototyping method must be carefully selected to meet the requirements of the component to be fabricated.

  9. HSI Prototypes for Human Systems Simulation Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Jokstad, Håkon [Idaho National Lab. (INL), Idaho Falls, ID (United States); McDonald, Rob [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    This report describes in detail the design and features of three Human System Interface (HSI) prototypes developed by the Institutt for Energiteknikk (IFE) in support of the U.S. Department of Energy’s Light Water Reactor Sustainability Program under Contract 128420 through Idaho National Laboratory (INL). The prototypes are implemented for the Generic Pressurized Water Reactor simulator and installed in the Human Systems Simulation Laboratory at INL. The three prototypes are: 1) Power Ramp display 2) RCS Heat-up and Cool-down display 3) Estimated time to limit display The power ramp display and the RCS heat-up/cool-down display are designed to provide good visual indications to the operators on how well they are performing their task compared to their target ramp/heat-up/cool-down rate. The estimated time to limit display is designed to help operators restore levels or pressures before automatic or required manual actions are activated.

  10. Generalizing Prototype Theory: A Formal Quantum Framework

    Directory of Open Access Journals (Sweden)

    Diederik eAerts

    2016-03-01

    Full Text Available Theories of natural language and concepts have been unable to model the flexibility, creativity, context-dependence, and emergence, exhibited by words, concepts and their combinations. The mathematical formalism of quantum theory has instead been successful in capturing these phenomena such as graded membership, situational meaning, composition of categories, and also more complex decision making situations, which cannot be modeled in traditional probabilistic approaches. We show how a formal quantum approach to concepts and their combinations can provide a powerful extension of prototype theory. We explain how prototypes can interfere in conceptual combinations as a consequence of their contextual interactions, and provide an illustration of this using an intuitive wave-like diagram. This quantum-conceptual approach gives new life to original prototype theory, without however making it a privileged concept theory, as we explain at the end of our paper.

  11. The Next Generation Transit Survey - Prototyping Phase

    CERN Document Server

    McCormac, James; Wheatley, Peter; West, Richard; Walker, Simon; Bento, Joao; Skillen, Ian; Faedi, Francesca; Burleigh, Matt; Casewell, Sarah; Chazelas, Bruno; Genolet, Ludovic; Gibson, Neale; Goad, Mike; Lawrie, Katherine; Ryans, Robert; Todd, Ian; Udry, Stephan; Watson, Christopher

    2016-01-01

    We present the prototype telescope for the Next Generation Transit Survey, which was built in the UK in 2008/09 and tested on La Palma in the Canary Islands in 2010. The goals for the prototype system were severalfold: to determine the level of systematic noise in an NGTS-like system; demonstrate that we can perform photometry at the (sub) millimagnitude level on transit timescales across a wide field; show that it is possible to detect transiting super-Earth and Neptune-sized exoplanets and prove the technical feasibility of the proposed planet survey. We tested the system for around 100 nights and met each of the goals above. Several key areas for improvement were highlighted during the prototyping phase. They have been subsequently addressed in the final NGTS facility which was recently commissioned at ESO Cerro Paranal, Chile.

  12. Magnetism, structures and stabilities of cluster assembled TM@Si nanotubes (TM = Cr, Mn and Fe): a density functional study.

    Science.gov (United States)

    Dhaka, Kapil; Bandyopadhyay, Debashis

    2016-08-01

    The present study reports transition metal (TM = Cr, Mn and Fe) doped silicon nanotubes with tunable band structures and magnetic properties by careful selection of cluster assemblies as building blocks using the first-principles density functional theory. We found that the transition metal doping and in addition, the hydrogen termination process can stabilize the pure silicon nanoclusters or cluster assemblies and then it could be extended as magnetic nanotubes with finite magnetic moments. Study of the band structures and density of states (DOS) of different empty and TM doped nanotubes (Type 1 to Type 4) show that these nanotubes are useful as metals, semiconductors, semi-metals and half-metals. These designer magnetic materials could be useful in spintronics and magnetic devices of nanoscale order. PMID:27430742

  13. Electrodeposited RE-TM (RE=Dy,Nd, Eu; TM =Co)Alloy Films and Their Magnetic Properties%电沉积RE-TM(RE=Dy,Nd,Eu;TM=Co)合金膜及其磁性质

    Institute of Scientific and Technical Information of China (English)

    范必强; 赖恒; 李加新; 黄志高

    2011-01-01

    在353 K的尿素-乙酰胺-NaBr-KBr熔体中,用恒电位电解法在Cu基片上制备了稀土RE(Dy,Nd,Eu)-铁族TM(Co)合金膜.利用循环伏安法研究了熔体的电化学行为.电化学实验结果表明,在Pt电极上,Co(Ⅱ)+2e→Co(0)是一步完全的不可逆反应,并测得Co(Ⅱ)在Pt电极上的传递系数a以及扩散系数D0.稀土元素(Dy,Nd,Eu)难以被单独沉积,但能被Co(Ⅱ)诱导共沉积.用EDS分析合金膜的成分及含量.用XRD和振动样品磁强计(VSM)分析样品退火前后的晶相和磁性能变化特征.实验结果表明,合金膜的表面形貌和磁性与其成分组成及沉积电位紧密相关,且稀土离子的被诱导能力取决于稀土与铁族原子之间的电负性差值.%Rare earth ( RE = Dy,Nd,Eu) -3d transition metal ( TM = Co) alloy films were codeposited on copper substrate in urea - acetarnide - NaBr - KBr melt at 355K. The cyclic voltammetry was used to study the electrochemical behavior,showing that the electroreduction of TM was irreversible in one step. The transfer coefficient a and the diffusion coefficient DO of Co2+ were measured. RE3+ could not be reduced alone, but it could be inductively codeposited with Co2+ . The composition of films was analyzed by EDS; the crystalline phases were investigated by XRD; the microstructures were observed by SEM;and the magnetic properties were measured by VSM. The experimental results reveal that, the surface morphologies and the magnetic properties of the RE - TM alloy films depend strongly on the composition and electrodeposition potential, furthermore the RE - induced codeposition ability is dominated by the electronegativity difference between RE and TM atoms.

  14. Design and Prototyping of Micro Centrifugal Compressor

    Institute of Scientific and Technical Information of China (English)

    Shimpei Mizuki; Gaku Minorikawa; Toshiyuki Hirano; Yuichiro Asaga; Naoki Yamaguchi; Yutaka Ohta; Eisuke Outa

    2003-01-01

    In order to establish the design methodology of ultra micro centrifugal compressor, which is the most important component of ultra micro gas turbine unit, a 10 times of the final target size model was designed, prototyped and tested. The problems to be solved for downsizing were examined and 2-dimensional impeller was chosen as the first model due to its productivity. The conventional 1D prediction method, CFD and the inverse design were attempted. The prototyped compressor was driven by using a turbocharger and the performance characteristics were measured.

  15. An Improved Prototype Pattern Selection Algorithm

    Institute of Scientific and Technical Information of China (English)

    Fang Xiuduan; Liu Binhan; Wang Weizhi

    2002-01-01

    The selection of prototype patterns plays a decisive part in the performance of synergetic neural network. Amongst the existing prototype pattern selection schemes, the learning algorithm based on information superposition presented by Wang[1] is the most efficient. However, it has a degree parameter greatly affecting the training process to be determined. To overcome this drawback, an improved algorithm is presented and discussed here. This approach makes use of Genetic Algorithm, a stochastic global search method, to search the global optimum of the unknown parameter in a small search space. Therefore, it converges fairly fast. The experimental results also demonstrate its effectivity.

  16. Modelling and Control of the Wavestar Prototype

    DEFF Research Database (Denmark)

    Hansen, Rico Hjerm; Kramer, Morten M.

    2011-01-01

    Algorithm (WPEA), applied to the full-scale Wavestar Prototype for maximizing energy extraction. The WPEA is optimized based on simulations of the point absorbers in different sea states. Hence, a presentation of a hydrodynamic model of the Wavestar is included in the paper. A simplified Power Take-Off (PTO......) is also added to the model, enabling the optimization of the WPEA to take into account the PTO constraints of PTO bandwidth and force limitations. The predicted results of the optimized WPEA are compared to real measurements from theWavestar Prototype, showing good compliance....

  17. Rapid Tooling Technique Based on Stereolithograph Prototype

    Institute of Scientific and Technical Information of China (English)

    丁浩; 狄平; 顾伟生; 朱世根

    2001-01-01

    Rapid tooling technique based on the sterelithograph prototype is investigated. The epoxy tooling technological process was elucidated. It is analyzed in detail that the epoxy resin formula is easy to cast, curing process, and release agents. The transitional plaster model is also proposed. The mold to encrust mutual.inductors with epoxy and mold to inject plastic soapboxes was made with the technique The tooling needs very little time and cost, for the process is only to achieve the nice replica of the prototype. It is benefit for the trial and small batch of production.

  18. Rapid Prototyping: Technologies, Materials and Advances

    Directory of Open Access Journals (Sweden)

    Dudek P.

    2016-06-01

    Full Text Available In the context of product development, the term rapid prototyping (RP is widely used to describe technologies which create physical prototypes directly from digital data. Recently, this technology has become one of the fastest-growing methods of manufacturing parts. The paper provides brief notes on the creation of composites using RP methods, such as stereolithography, selective laser sintering or melting, laminated object modelling, fused deposition modelling or three-dimensional printing. The emphasis of this work is on the methodology of composite fabrication and the variety of materials used in these technologies.

  19. Somatic 'soluble' adenylyl cyclase isoforms are unaffected in Sacy tm1Lex/Sacy tm1Lex 'knockout' mice.

    Directory of Open Access Journals (Sweden)

    Jeanne Farrell

    Full Text Available BACKGROUND: Mammalian Soluble adenylyl cyclase (sAC, Adcy10, or Sacy represents a source of the second messenger cAMP distinct from the widely studied, G protein-regulated transmembrane adenylyl cyclases. Genetic deletion of the second through fourth coding exons in Sacy(tm1Lex/Sacy(tm1Lex knockout mice results in a male sterile phenotype. The absence of any major somatic phenotype is inconsistent with the variety of somatic functions identified for sAC using pharmacological inhibitors and RNA interference. PRINCIPAL FINDINGS: We now use immunological and molecular biological methods to demonstrate that somatic tissues express a previously unknown isoform of sAC, which utilizes a unique start site, and which 'escapes' the design of the Sacy(tm1Lex knockout allele. CONCLUSIONS/SIGNIFICANCE: These studies reveal increased complexity at the sAC locus, and they suggest that the known isoforms of sAC play a unique function in male germ cells.

  20. Systems Prototyping with Fourth Generation Tools.

    Science.gov (United States)

    Sholtys, Phyllis

    1983-01-01

    The development of information systems using an engineering approach that uses both traditional programing techniques and fourth generation software tools is described. Fourth generation applications tools are used to quickly develop a prototype system that is revised as the user clarifies requirements. (MLW)

  1. Prototype HL-LHC magnet undergoes testing

    CERN Multimedia

    Corinne Pralavorio

    2016-01-01

    A preliminary short prototype of the quadrupole magnets for the High-Luminosity LHC has passed its first tests.   The first short prototype of the quadrupole magnet for the High Luminosity LHC. (Photo: G. Ambrosio (US-LARP and Fermilab), P. Ferracin and E. Todesco (CERN TE-MSC)) Momentum is gathering behind the High-Luminosity LHC (HL-LHC) project. In laboratories on either side of the Atlantic, a host of tests are being carried out on the various magnet models. In mid-March, a short prototype of the quadrupole magnet underwent its first testing phase at the Fermilab laboratory in the United States. This magnet is a pre-prototype of the quadrupole magnets that will be installed near to the ATLAS and CMS detectors to squeeze the beams before collisions. Six quadrupole magnets will be installed on each side of each experiment, giving a total of 24 magnets, and will replace the LHC's triplet magnets. Made of superconducting niobium-tin, the magnets will be more powerful than their p...

  2. Performance Evaluation of the Wavestar Prototype

    DEFF Research Database (Denmark)

    Kramer, Morten; Marquis, Laurent; Frigaard, Peter

    2011-01-01

    Wave Star has produced and installed a test and demonstration Wave Energy Converter (WEC) by Roshage pier near Hanstholm at the west coast of Denmark. The test unit is a prototype test section of a complete commercial WEC. After an initial period of finalizing the installation and testing, the WE...

  3. Status of the CALICE AHCAL engineering prototype

    Energy Technology Data Exchange (ETDEWEB)

    Eldwan, Brianne [DESY (Germany); Collaboration: CALICE-D-Collaboration

    2015-07-01

    In the CALICE Collaboration are developed calorimeters for a future e{sup +}e{sup -} Linear Collider. One approach is called Particle Flow which requires highly granular calorimeters thus to achieve a jet energy resolution of 3-4%. The CALICE Collaboration is developing concepts and prototypes for Particle Flow optimized calorimeters with various readout technologies. The Analog Hadronic Calorimeter (AHCAL) is one of the concepts based on 3 x 3 cm{sup 2} scintillator tiles with Silicon Photomultipliers. The performance and suitability has been proven in the former physics prototype. The current focus of the second generation engineering prototype is on the full scalability of the detector. In 2014, two test beam periods happened at the PS at CERN, with an iron stack structure designed for the final detector (1 m{sup 3}) and 15 active layers (including 3 ScECAL layers). This talk focuses on the engineering prototype commissioning phase before testbeam, the monitoring of the calorimeter during data taking and a first look into the data taken at the PS.

  4. An empirical investigation of architectural prototyping

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2010-01-01

    Architectural prototyping is the process of using executable code to investigate stakeholders’ software architecture concerns with respect to a system under development. Previous work has established this as a useful and cost-effective way of exploration and learning of the design space of a syst...

  5. Conceptual Design of a Prototype LSST Database

    Energy Technology Data Exchange (ETDEWEB)

    Nikolaev, S; Huber, M E; Cook, K H; Abdulla, G; Brase, J

    2004-10-07

    This document describes a preliminary design for Prototype LSST Database (LSST DB). They identify key components and data structures and provide an expandable conceptual schema for the database. The authors discuss the potential user applications and post-processing algorithm to interact with the database, and give a set of example queries.

  6. Prototype bucket foundation for wind turbines

    DEFF Research Database (Denmark)

    Ibsen, Lars Bo; Liingaard, Morten

    The first full scale prototype bucket foundation for wind turbines has been installed in October 2002 at Aalborg University offshore test facility in Frederikshavn, Denmark. The suction caisson and the wind turbine have been equipped with an online monitoring system, consisting of 15 accelerometers...... capable of simulating dynamic frequency dependent behaviour of the structure-foundation system....

  7. Design data brochure: SIMS prototype system 2

    Energy Technology Data Exchange (ETDEWEB)

    1977-12-01

    Information is provided on the design and performance of the IBM SIMS Prototype System 2, solar domestic hot water system, for single family residences. The document provides sufficient data to permit procurement, installation, operation, and maintenance by qualified architectural engineers or contractors.

  8. Full scale prototype laboratory for architecture students

    NARCIS (Netherlands)

    Eekhout, A.C.J.M.; Van Swieten, P.M.J.

    2011-01-01

    Innovation in prefabrication with new technologies in product development of building components together with the important role materialization is playing in the education of architectural engineers and building technology designers are the main motifs for full scale material prototyping in the Ma

  9. Integral Measurement of Dipole Prototype of CSR

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The dipole prototype is C type used as bending magnet of the injection beam line in CSR, and acts as a model of the dipoles in the CSR main ring simultaneously. The designed relative uniformity of good field is 0.001 in 100 mm width. The results of the local distribution and transfunction at transverse profile measured

  10. Tests of Cathode Strip Chamber Prototypes

    CERN Document Server

    Bonushkin, Yuri; Chrisman, David; Durkin, S; Ferguson, Thomas; Giacomelli, Paolo; Gorn, William; Hauser, Jay; Hirschfelder, J; Hoftiezer, John; Hoorani, Hafeez R; Kisselev, Oleg; Klem, Daniel; Korytov, Andrey; Layter, John G; Lennous, Paul; Ling, Ta-Yung; Matthey, Christina; Medved, Serguei; Minor, C; Mitselmakher, Guenakh; Müller, Thomas; Otwinowski, Stanislaw; Preston, L; Prokofiev, O E; Rush, Chuck J; Schenk, P; Sedykh, Yu; Smirnov, Igor; Soulimov, V; Vaniachine, A; Vercelli, T; Wuest, Craig R; Zeng, Ji-Yang; von Goeler, Eberhard

    1997-01-01

    We report on the results of testing two six-layer 0.6 x 0.6 cm^2 cathode strip chamber ( CSC) prototypes in a muon beam at CERN. The prototypes were designed to simulate sections of the end-cap muon system of the Compact Muon Solenoid ( CMS) detector which will be installed at the Large Hadron Collider ( LHC). We measured the spatial and time resolutions of each chamber for different gains, different orientations with respect to the beam direction and different strength magnetic fields. The single-layer spatial resolution of a prototype with a strip pitch of 15.88 mm ranged from 78 micron to 468 micron, depending on whether the particle passed between two cathode strips or through the center of a strip; its six-layer resolution was found to be 44 micron. The single-layer spatial resolution of a prototype with a strip pitch of 6.35 mm ranged from 54 to 66 micron; its six-layer resolution w as found to be 23 micron. The efficiency for collecting an anode wire signal from one of six layers within a 20 ns time wi...

  11. Moessbauer study of the cubic Laves phase intermetallic compound TmFe/sub 2/

    Energy Technology Data Exchange (ETDEWEB)

    Bleaney, B.; Bowden, G.J.; Cadogan, J.M. (New South Wales Univ., Kensington (Australia). School of Physics); Day, R.K.; Dunlop, J.B. (Commonwealth Scientific and Industrial Research Organization, Lindfield (Australia). Div. of Applied Physics)

    1982-04-01

    The results of a /sup 169/Tm and /sup 57/Fe Moessbauer study of the cubic Laves compound TmFe/sub 2/ over the temperature range 1.3-550 K are presented and discussed. The new results are used, in conjunction with existing NMR, Moessbauer and magnetic anisotropy data for TmFe/sub 2/ and Tm metal, to deduce a value of Psub(4f) 536 +- 14 MHz for the saturation value of the first excited state of the /sup 169/Tm nucleus. Estimates are also given for the exchange field ..mu..sub(B)Bsub(ex)(T = O K)/ksub(B) = 153 +- 3 K acting on the Tm/sup 3 +/ ion in TmFe/sub 2/, the quadrupole moment of the I = 3/2 state of the /sup 169/Tm nucleus. Q = -1.36 +- 0.11 b, and the lattice contribution to the nuclear quadrupole interaction in Tm metal, Psub(c) = -54.8 +- 5 MHz (for Q = -1.20 +- 0.07 b) and Psub(c) = -61 +- 8 MHz (for Q = -1.36 +- 0.11 b). In addition estimates are given for the various transferred and parent hyperfine fields in TmFe.

  12. TM4SF5 suppression disturbs integrin α5-related signalling and muscle development in zebrafish.

    Science.gov (United States)

    Choi, Yoon-Ju; Kim, Hyun Ho; Kim, Jeong-Gyun; Kim, Hye-Jin; Kang, Minkyung; Lee, Mi-Sook; Ryu, Jihye; Song, Haeng Eun; Nam, Seo Hee; Lee, Doohyung; Kim, Kyu-Won; Lee, Jung Weon

    2014-08-15

    TM4SF5 (transmembrane 4 L six family member 5) is involved in EMT (epithelial-mesenchymal transition) for liver fibrosis and cancer metastasis; however, the function(s) of TM4SF5 during embryogenesis remains unknown. In the present study the effects of TM4SF5 on embryogenesis of zebrafish were investigated. tm4sf5 mRNA was expressed in the posterior somites during somitogenesis and in whole myotome 1 dpf (day post-fertilization). tm4sf5 suppression impaired development of the trunk with aberrant morphology of muscle fibres and altered expression of integrin α5. The arrangement and adhesion of muscle cells were abnormally disorganized in tm4sf5 morphants with reduced muscle fibre masses, where integrin α5-related signalling molecules, including fibronectin, FAK (focal adhesion kinase), vinculin and actin were aberrantly localized, compared with those in control fish. Aberrant muscle developments in tm4sf5 morphants were recovered by additional tm4sf5 or integrin α5 mRNA injection. Such a role for TM4SF5 was observed in the differentiation of C2C12 mouse myoblast cells to multinuclear muscle cells. Taken together, the results show that TM4SF5 controls muscle differentiation via co-operation with integrin α5-related signalling. PMID:24897542

  13. Ares I-X Ground Diagnostic Prototype

    Science.gov (United States)

    Schwabacher, Mark; Martin, Rodney; Waterman, Robert; Oostdyk, Rebecca; Ossenfort, John; Matthews, Bryan

    2010-01-01

    Automating prelaunch diagnostics for launch vehicles offers three potential benefits. First, it potentially improves safety by detecting faults that might otherwise have been missed so that they can be corrected before launch. Second, it potentially reduces launch delays by more quickly diagnosing the cause of anomalies that occur during prelaunch processing. Reducing launch delays will be critical to the success of NASA's planned future missions that require in-orbit rendezvous. Third, it potentially reduces costs by reducing both launch delays and the number of people needed to monitor the prelaunch process. NASA is currently developing the Ares I launch vehicle to bring the Orion capsule and its crew of four astronauts to low-earth orbit on their way to the moon. Ares I-X will be the first unmanned test flight of Ares I. It is scheduled to launch on October 27, 2009. The Ares I-X Ground Diagnostic Prototype is a prototype ground diagnostic system that will provide anomaly detection, fault detection, fault isolation, and diagnostics for the Ares I-X first-stage thrust vector control (TVC) and for the associated ground hydraulics while it is in the Vehicle Assembly Building (VAB) at John F. Kennedy Space Center (KSC) and on the launch pad. It will serve as a prototype for a future operational ground diagnostic system for Ares I. The prototype combines three existing diagnostic tools. The first tool, TEAMS (Testability Engineering and Maintenance System), is a model-based tool that is commercially produced by Qualtech Systems, Inc. It uses a qualitative model of failure propagation to perform fault isolation and diagnostics. We adapted an existing TEAMS model of the TVC to use for diagnostics and developed a TEAMS model of the ground hydraulics. The second tool, Spacecraft Health Inference Engine (SHINE), is a rule-based expert system developed at the NASA Jet Propulsion Laboratory. We developed SHINE rules for fault detection and mode identification. The prototype

  14. Microtox(TM) characterization of foundry sand residuals

    Science.gov (United States)

    Bastian, K.C.; Alleman, J.E.

    1998-01-01

    Although foundry residuals, consisting mostly of waste Sands, represent a potentially attractive, high-volume resource for beneficial reuse applications (e.g. highway embankment construction), prospective end users are understandably concerned about unforeseen liabilities stemming from the use of these residuals. This paper, therefore, focuses on the innovative use of a microbial bioassay as a means of developing a characterization of environmental suitability extending beyond the analytical coverage already provided by mandated chemical-specific tests (i.e., TCLP, etc.). Microtox(TM) bioassays were conducted on leachates derived from residuals obtained at a wide range of facilities, including: 11 gray and ductile iron foundries plus one each steel and aluminum foundries. In addition, virgin sand samples were used to establish a relative 'natural' benchmark against which the waste foundry sands could then be compared in terms of their apparent quality. These bioassay tests were able to effectively 'fingerprint' those residuals whose bioassay behavior was comparable to that of virgin materials. In fact, the majority of gray and ductile iron foundry residuals tested during this reported study elicited Microtox(TM) response levels which fell within or below the virgin sand response range, consequently providing another quantifiable layer of Support for this industry's claim that their sands are 'cleaner than dirt.' However, negative Microtox(TM) responses beyond that of the virgin sands were observed with a number of foundry samples (i.e. four of the 11 gray or ductile iron sands plus both non-iron sands). Therefore, the latter results would suggest that these latter residuals be excluded from beneficial reuse for the immediate future, at least until the cause and nature of this negative response has been further identified.

  15. Commercialization of Medium Voltage HTS Triax TM Cable Systems

    Energy Technology Data Exchange (ETDEWEB)

    Knoll, David

    2012-12-31

    The original project scope that was established in 2007 aimed to install a 1,700 meter (1.1 mile) medium voltage HTS Triax{TM} cable system into the utility grid in New Orleans, LA. In 2010, however, the utility partner withdrew from the project, so the 1,700 meter cable installation was cancelled and the scope of work was reduced. The work then concentrated on the specific barriers to commercialization of HTS cable technology. The modified scope included long-length HTS cable design and testing, high voltage factory test development, optimized cooling system development, and HTS cable life-cycle analysis. In 2012, Southwire again analyzed the market for HTS cables and deemed the near term market acceptance to be low. The scope of work was further reduced to the completion of tasks already started and to testing of the existing HTS cable system in Columbus, OH. The work completed under the project included: • Long-length cable modeling and analysis • HTS wire evaluation and testing • Cable testing for AC losses • Optimized cooling system design • Life cycle testing of the HTS cable in Columbus, OH • Project management. The 200 meter long HTS Triax{TM} cable in Columbus, OH was incorporated into the project under the initial scope changes as a test bed for life cycle testing as well as the site for an optimized HTS cable cooling system. The Columbus cable utilizes the HTS TriaxTM design, so it provided an economical tool for these of the project tasks.

  16. Automated Tow Placed LaRC(TM)-PETI-5 Composites

    Science.gov (United States)

    Hou, T. H.; Belvin, H. L.; Johnston, N. J.

    2001-01-01

    LaRC(TM)-PETI-5 is a PhenylEthynyl-Terminated Imide resin developed at NASA Langley Research Center (LaRC) during the 1990s. It offers a combination of attractive composite and adhesive properties. IM7/LaRC(TM)-PETI-5 composites exhibit thermal and thermo-oxidative stability typical of polyimides, superior chemical resistance and processability, excellent mechanical properties, toughness and damage tolerance. It was selected for study in the High Speed Research program aimed at developing technologies for a future supersonic aircraft, the High Speed Civil Transport, with a projected life span of 60 000 h at a cruise speed up to Mach 2.4. Robust autoclave processing cycles for LaRC(TM)-PETI-5 composites have been thoroughly designed and demonstrated, which involved hand lay-up of solvent-ladened 'wet' prepregs. However, this type of processing is not only costly but also environmentally unfriendly. Volatile management and shrinkage could become serious problems in the fabrication of large complex airframe structural subcomponents. Robotic tow placement technology utilizing 'dry' material forms represents a new fabrication process which overcomes these deficiencies. This work evaluates and compares mechanical properties of composites fabricated by heated head automated tow placement (dry process) with those obtained by hand lay-up/autoclave fabrication (wet process). Thermal and rheological properties of the robotically as-placed uncured composites were measured. A post-cure cycle was designed due to the requirement of the PETI-5 resin for a 370 C/1 h hold to reach full cure, conditions which cannot be duplicated during heated head robotic placement. Mechanical properties such as 0 degree flexural strength and modulus, open hole tensile and compressive strength and moduli, reduced section compression dogbone compressive strength, and modified zippora-medium small (MZ-MS) tensile and compressive properties were obtained on the post-cured panels. These properties

  17. Ultraviolet and visible upconversion luminescence of Tm(0.1)Yb(5):FOV oxyfluoride nanophase vitroceramics

    Institute of Scientific and Technical Information of China (English)

    N.; SAWANOBOI; M.; OHTSUKA

    2008-01-01

    The ultraviolet upconversion luminescence of Tm3+ ions sensitized by Yb3+ ions in oxyfluoride nanophase vitroceramics when excited by a 975 nm diode laser was studied. An ultraviolet upconversion luminescence line positioned at 363.6 nm was found. It was attributed to the fluorescence transition of 1D2→3H6 of Tm3+ ion. Sev- eral visible upconversion luminescence lines at 450.7 nm, (477.0 nm, 462.5 nm), 648.5 nm, (680.5 nm, 699.5 nm) and (777.2 nm, 800.7 nm) were also found, which result respectively from the fluorescence transitions of 1D2→3F4, 1G4→3H6, 1G4→3F4, 3F3→3H6 and 3H4→3H6 of Tm3+ ion. The careful measurement and analysis of the variation of upconversion luminescence intensity F as a function of the 975 nm pumping laser power P prove that the upconversion luminescence of 1D2 state is partly a five-photon upconversion luminescence, and the upconversion lumines- cence of 1G4 state and 3H4 state are respectively the three-photon and two-photon upconversion luminescence. The theoretical analysis suggested that the upcon- version mechanism of the 363.6 nm 1D2→3H6 upconversion luminescence is partly the cross energy transfer of {3H4(Tm3+)→3F4(Tm3+), 1G4(Tm3+)→1D2(Tm3+)} and {1G4(Tm3+)→3F4(Tm3+), 3H4(Tm3+)→1D2(Tm3+)} between Tm3+ ions. In addition, the upconversion luminescence of 1G4 and 3H4 state results respectively from the se- quential energy transfer {2F5/2(Yb3+)→2F7/2(Yb3+), 3H4(Tm3+)→1G4(Tm3+)} and {2F5/2(Yb3+) →2F7/2(Yb3+), 3F4(Tm3+)→3F2(Tm3+)} from Yb3+ ions to Tm3+ ions.

  18. Image Analysis via Fuzzy-Reasoning Approach: Prototype Applications at NASA

    Science.gov (United States)

    Dominguez, Jesus A.; Klinko, Steven J.

    2004-01-01

    A set of imaging techniques based on Fuzzy Reasoning (FR) approach was built for NASA at Kennedy Space Center (KSC) to perform complex real-time visual-related safety prototype tasks, such as detection and tracking of moving Foreign Objects Debris (FOD) during the NASA Space Shuttle liftoff and visual anomaly detection on slidewires used in the emergency egress system for Space Shuttle at the launch pad. The system has also proved its prospective in enhancing X-ray images used to screen hard-covered items leading to a better visualization. The system capability was used as well during the imaging analysis of the Space Shuttle Columbia accident. These FR-based imaging techniques include novel proprietary adaptive image segmentation, image edge extraction, and image enhancement. Probabilistic Neural Network (PNN) scheme available from NeuroShell(TM) Classifier and optimized via Genetic Algorithm (GA) was also used along with this set of novel imaging techniques to add powerful learning and image classification capabilities. Prototype applications built using these techniques have received NASA Space Awards, including a Board Action Award, and are currently being filed for patents by NASA; they are being offered for commercialization through the Research Triangle Institute (RTI), an internationally recognized corporation in scientific research and technology development. Companies from different fields, including security, medical, text digitalization, and aerospace, are currently in the process of licensing these technologies from NASA.

  19. Prototype Design of Plasma-Nitriding Apparatus for Components of Industries

    International Nuclear Information System (INIS)

    An apparatus to carry-out plasma-nitriding surface treatment has been designed. The construction was planned as a prototype for a larger system at industrial scale. The design was based on a similar apparatus currently operating at the Accelerator Laboratory at the P3TM-BATAN, in Yogyakarta. The system consists of a main vacuum chamber from steel SS-304, 45 cm OD, 55 cm height and is equipped with a nitriding chamber in the inner part that also functions as a plasma container (Quartz, cylindrical, 38 cm OD, 40 cm height). The system utilized an anode-cathode pair to generate nitrogen plasma, as well as to accelerate and direct the positively-charged-plasma toward the surface of the material to be treated. The pressure inside the chamber is designed to be in the region of 10-3 mb with a temperature between 350-590 oC. Pulsated DC high voltage can be set at 1-50 kV at a frequency between 100-1000 Hz and current 1- 50 mA. The safety and reliability features have been designed to obtain nitriding results that are in accordance with the required technical specification as well as economical constrain. It is hoped that this device can become a prototype for future development of an industrial scale plasma-nitriding apparatus. (author)

  20. ADAPT(tm trocar use for laparoscopic procedures in equidea

    Directory of Open Access Journals (Sweden)

    P.P.M. Teixeira

    2016-02-01

    Full Text Available O objetivo deste trabalho é descrever o uso do trocater modelo Adapt(tm no acesso laparoscópico em animais da família dos equídeos. O procedimento cirúrgico foi realizado em 15 equídeos (quatro jumentas, seis cavalos e cinco éguas, com peso médio de 320kg (290kg e 450kg, pesos máximo e mínimo, respectivamente. Os pacientes foram mantidos em posição quadrupedal, sob sedação e bloqueio local. Primeiramente, realizou-se o preparo asséptico, e o acesso foi feito pelo flanco direito ou pelo esquerdo, dependendo da estrutura a ser visualizada. Em todos os procedimentos, foi utilizado o trocater modelo Seal AdaptTM Ports (Teleflex Medical Introduces TautTM, USA, com diâmetro de 12mm. Inicialmente se fez uma incisão de pele de aproximadamente 15mm para inserção da ponta do trocater. Este foi inserido na ferida cirúrgica, realizando-se movimentos de 180º em sentido horário e anti-horário, até atingir a cavidade abdominal. Após esta etapa, o obturador do trocater foi retirado, e a ótica inserida para confirmar o acesso à cavidade abdominal. A síntese das camadas superficiais da muscular foi realizada com fio nylon nº 0, em um padrão Sultan, e posteriormente a dermorrafia, também com nylon nº 0, no padrão de Wolf. O equipamento apresentou eficiência nos procedimentos de dissecação das camadas subcutânea, musculares e peritônio, não ocorrendo significativa hemorragia nessas camadas. Em um paciente muar, ocorreu afastamento do peritônio parietal, e em alguns casos (40% ocorreu pequeno enfisema subcutâneo no pós-cirúrgico. Todos os pacientes apresentaram boa cicatrização da ferida cirúrgica. O trocater modelo AdaptTM mostrou-se eficiente na abordagem laparoscópica em equinos, apresentando segurança em se estabelecer o acesso e versatilidade no emprego de diversos instrumentais.

  1. Ho:YLF Laser Pumped by TM:Fiber Laser

    Directory of Open Access Journals (Sweden)

    Mizutani Kohei

    2016-01-01

    Full Text Available A 2-micron Ho:YLF laser end-pumped by 1.94-micron Tm:fiber laser is described. A ring resonator of 3m length is adopted for the oscillator. The laser is a master oscillator and an amplifier system. It is operated at high repetition rate of 200-5000 Hz in room temperature. The laser outputs were about 9W in CW and more than 6W in Q-switched operation. This laser was developed to be used for wind and CO2 measurements.

  2. Wakefield calculation for superconducting TM110 cavity without azimuthal symmetry

    Energy Technology Data Exchange (ETDEWEB)

    Bellantoni, Leo; /Fermilab; Burt, Graeme; /Lancaster U.

    2006-08-01

    The 3.9GHz TM{sub 110} mode deflecting cavity developed at FNAL has many applications, including use as a longitudinal bunch profile diagnostic, and as a crab cavity candidate for the ILC. These applications involve beams with substantial time structure. For the 13-cell version intended for the bunch profile application, long-range wakes have been evaluated in the frequency domain and short-range wakes have been evaluated in the time domain. Higher-order interactions of the main field in the cavity with the beam have also been parameterized. Pedagogic derivations are included as appendices.

  3. Influence of Tm-doping on microstructure and luminescence behavior of barium strontium titanate thick films

    Energy Technology Data Exchange (ETDEWEB)

    Wang Jingyang [School of Materials Science and Engineering, Hubei University, Wuhan, 430062 (China); Zhang Tianjin, E-mail: tj65zhang@yahoo.com.cn [School of Materials Science and Engineering, Hubei University, Wuhan, 430062 (China); Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei University, Wuhan, 430062 (China); Pan Ruikun; Ma Zhijun; Wang Jinzhao [School of Materials Science and Engineering, Hubei University, Wuhan, 430062 (China)

    2012-01-15

    Tm-doped Ba{sub 0.8}Sr{sub 0.2}TiO{sub 3} thick films were prepared by the screen-printing technique on the alumina substrate. The microstructure of the Tm-doped BST thick films was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and Raman spectroscopy, respectively. All the samples showed a typical perovskite polycrystalline structure when sintered at 1260 Degree-Sign C. The substitution behavior of Tm{sup 3+} ion in BST was found to change with increasing the Tm{sup 3+} concentration. The observed Tm-related red emission reaches the maximum at 0.2 mol% Tm{sup 3+} concentration. The effects of concentration quenching on the luminescence intensity were discussed.

  4. The minor binding pocket: a major player in 7TM receptor activation

    DEFF Research Database (Denmark)

    Rosenkilde, Mette Marie; Benned-Jensen, Tau; Frimurer, Thomas M.;

    2010-01-01

    From the deep part of the main ligand-binding crevice, a minor, often shallower pocket extends between the extracellular ends of transmembrane domains (TM)-I, II, III and VII of 7TM receptors. This minor binding pocket is defined by a highly conserved kink in TM-II that is induced by a proline...... residue located in one of two adjacent positions. Here we argue that this minor binding pocket is important for receptor activation. Functional coupling of the receptors seems to be mediated through the hydrogen bond network located between the intracellular segments of these TMs, with the allosteric...... interface between TM-II and TM-VII being of particular significance. Importantly, the minor binding pocket, especially the proline-kink in TM-II, is involved in G protein versus arrestin pathway-biased signaling, for example in the angiotensin AT1 system. Consequently, this pocket could be specifically...

  5. Sweep potential deposition of Tm-Ni-Co alloy films in dimethylsulfoxide

    Institute of Scientific and Technical Information of China (English)

    YUAN Dingsheng; LIU Yingliang; ZHANG Jingxian; LIU Guankun; TONG Yexiang

    2004-01-01

    The Tm-Ni-Co alloy films have been prepared by the sweep potential deposition technique. The surface appearance of Tm-Ni-Co alloy films was silver, smooth and adhesive. The surfaces of Tm-Ni-Co alloy films observed by scanning electron microscope (SEM) were uniform, adhesive and compact. The sizes of metallic grains were about 80-100 nm, 100-200 amorphous as proven by the X-ray diffraction (XRD).

  6. ROMANIAN MOBILE TELECOMMUNICATIONS CLIENTSâ€(tm) CONSUMPTION BEHAVIOUR WITHIN THE CURRENT ECONOMIC-FINANCIAL CRISIS

    OpenAIRE

    Marcu Nicu; Meghisan Georgeta-Madalina

    2012-01-01

    The paper will analyze the consumption behaviour of the Orange mobile telephony companyâ€(tm)s clients towards its servicesâ€(tm) characteristics within the current economic financial crisis, taking into consideration the following elements: the low tariffs (for calls/ subscriptions/ other services), the quality of calls/ of sound, the network coverage within the territory, the companyâ€(tm)s reputation, the negotiated offer, the quality and availability of the customer care service, the dive...

  7. LUMINEX100TM MASA的技术原理及临床应用

    Institute of Scientific and Technical Information of China (English)

    李宁利

    2009-01-01

    LUMINEX100TM MASA(Multi—Analyte Suspension Array)是美国Luminex公司开发的生物芯片系统,在生物芯片技术发展的历史中,LUMINEX100TM MASA具有里程碑地位。本文将对LUMINEX100TM MASA系统组成、工作原理、特点及临床应用进行综述。

  8. Molekulare Charakterisierung der neuroprotektiven Wirkung transmembraner Proteine der TM9-Superfamilie und der TMEFF-Proteine

    OpenAIRE

    Wiegand, Anne Katharina Gisela

    2013-01-01

    Im Rahmen dieser Dissertation sollte die neuroprotektive Wirkung der transmembranen Proteine TM9SF1 und TMEFF1 untersucht werden. Es wurden relative Expressionsanalysen der beiden Proteine an SHSY5Y-Zellen und humanen Gewebeproben im Vergleich zu house-keeping-Genen sowie Klonierungsversuche von TM9SF1 durchgeführt. Im Ergebnis wurden die neuroprotektiven, antiapoptotischen und wachstumsregulierenden Eigenschaften von TM9SF1 und TMEFF1 bestätigt. The experiments within the framework of...

  9. 单脉冲跟踪TM01模耦合器的设计%Design of TM01-mode Coupler for Monopulse Tracking

    Institute of Scientific and Technical Information of China (English)

    詹英; 李振生; 张文静

    2014-01-01

    Monopulse tracking is one of the key technologies for auto-tracking antennas.A wide band TM01-mode coupler which is widely usedin monopulse tracking antennas is described.By analyzing and introducing the tracking theory and designing method,a TM01-mode coupler operating in Ka-band is simulated with HFSS.The final design is realized and the best result is obtained after optimizing the whole coupler.The result shows that the TM01-mode coupler can be widely used in monopulse tracking antennas in the future.%单脉冲跟踪是天线自动跟踪技术研究中的关键技术之一。介绍了一种广泛应用于单脉冲跟踪天线中的宽频带TM01模耦合器,详细分析了TM01耦合器的跟踪原理和设计方法。应用HFSS仿真软件设计了工作于C频段的TM01模耦合器,通过理论分析得到波导腔体和耦合部分的尺寸初值,进行整体仿真优化,完成设计并给出仿真结果。仿真结果表明,该TM01耦合器在3�6~4�2 GHz的带宽内,驻波比小于1�1, TM01模的耦合度大于-8 dB, TM01模和TE11模之间隔离度大于35 dB,高次模抑制度大于52 dB,满足单脉冲跟踪的要求。

  10. Cardiovascular angiography system Infinix{sub TM} CB; Shinzoyo junkanki shindan system Infinix{sub TM} CB

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    A cardiovascular angiography system Infinix{sub TM} CB is developed, which is a dedicated system for cardiovascular catheter treatment (intervention), from PTCA (percutaneous transluminal coronary angioplasty) down, capable of two-way biplanar photography. It is designed to be thoroughly operator-friendly, and some of its features are stated below. It is capable of high-speed biplanar positioning at the maximum speed of 10 degrees/second (25% faster than in the conventional type). A side beam vertical motion mechanism is provided rendering biplanar framing faster and easier. Hyper-handling is embodied with ergonomics introduced into the system. (translated by NEDO)

  11. Cardiovascular angiography system Infinix[sub TM] CB. Shinzoyo junkanki shindan system Infinix[sub TM] CB

    Energy Technology Data Exchange (ETDEWEB)

    1999-03-01

    A cardiovascular angiography system Infinix[sub TM] CB is developed, which is a dedicated system for cardiovascular catheter treatment (intervention), from PTCA (percutaneous transluminal coronary angioplasty) down, capable of two-way biplanar photography. It is designed to be thoroughly operator-friendly, and some of its features are stated below. It is capable of high-speed biplanar positioning at the maximum speed of 10 degrees/second (25% faster than in the conventional type). A side beam vertical motion mechanism is provided rendering biplanar framing faster and easier. Hyper-handling is embodied with ergonomics introduced into the system. (translated by NEDO)

  12. TM4SF1 Promotes Proliferation, Invasion, and Metastasis in Human Liver Cancer Cells

    Science.gov (United States)

    Huang, Yu-Kun; Fan, Xue-Gong; Qiu, Fu

    2016-01-01

    Transmembrane 4 superfamily member 1 (TM4SF1) is a member of tetraspanin family, which mediates signal transduction events regulating cell development, activation, growth and motility. Our previous studies showed that TM4SF1 is highly expressed in liver cancer. HepG2 cells were transfected with TM4SFl siRNA and TM4SF1-expressing plasmids and their biological functions were analyzed in vitro and in vivo. HepG2 cells overexpressing TM4SF1 showed reduced apoptosis and increased cell migration in vitro and enhanced tumor growth and metastasis in vivo, whereas siRNA-mediated silencing of TM4SF1 had the opposite effect. TM4SF1 exerts its effect by regulating a few apoptosis- and migration-related genes including caspase-3, caspase-9, MMP-2, MMP-9 and VEGF. These results indicate that TM4SF1 is associated with liver tumor growth and progression, suggesting that TM4SF1 may be a potential target for treatment of liver cancer in future. PMID:27153056

  13. Mechatronic Prototype of Parabolic Solar Tracker.

    Science.gov (United States)

    Morón, Carlos; Díaz, Jorge Pablo; Ferrández, Daniel; Ramos, Mari Paz

    2016-01-01

    In the last 30 years numerous attempts have been made to improve the efficiency of the parabolic collectors in the electric power production, although most of the studies have focused on the industrial production of thermoelectric power. This research focuses on the application of this concentrating solar thermal power in the unexplored field of building construction. To that end, a mechatronic prototype of a hybrid paraboloidal and cylindrical-parabolic tracker based on the Arduido technology has been designed. The prototype is able to measure meteorological data autonomously in order to quantify the energy potential of any location. In this way, it is possible to reliably model real commercial equipment behavior before its deployment in buildings and single family houses. PMID:27314359

  14. Video prototype of the interactive operating theatre

    DEFF Research Database (Denmark)

    2004-01-01

    already present in the operation theatre. The ActiveTheatre prototype has been developed in close co- operation with surgeons and nurses at a local hospital. The work on the proto- type and our initial evaluations have provided an insight into how to design, capture and access applications that are going......Building capture and access (C&A) applications for use in the operation theatre differs greatly from C&A applications built to support other settings e.g. meeting rooms or classrooms. Based on field studies of surgical operations, this paper explores how to design C&A applications for the operation...... theatre. Based on the findings from our field work, we have built the ActiveTheatre, a C&A prototype. ActiveTheatre is built to support collaboration in and around the operating theatre, to capture events instead of automatically capturing eve- rything, and to be integrated with existing applications...

  15. The PIAA Coronagraph Prototype: First Laboratory Results.

    Science.gov (United States)

    Pluzhnik, Eugene; Guyon, O.; Colley, S.; Gallet, B.; Ridgway, S.; Woodruff, R.; Tanaka, S.; Warren, M.

    2006-12-01

    The phase-induced amplitude apodization (PIAA) coronagraph combines the main advantages of classical pupil apodization with high throughput ( 100%), high angular resolution ( 2λ/D) and low chromaticity. These advantages can allow direct imaging of nearby extrasolar planets with a 4-meter telescope. The PIAA coronagraph laboratory prototype has been successfully manufactured and starts to operate at the Subary Telescope facility. We present here our first laboratory results with this prototype where we have achieved 2x10-6 contrast within 2 λ/D. We also discuss the main constrains limiting the contrast and describe our future efforts. This work was carried out under JPL contract numbers 1254445 and 1257767 for Development of Technologies for the Terrestrial Planet Finder Mission, with the support and hospitality of the National Astronomical Observatory of Japan.

  16. A prototype radonmeter for seismic surveillance

    Directory of Open Access Journals (Sweden)

    B. Porfidia

    1997-06-01

    Full Text Available A new 222Rn monitoring prototype has been designed, assembled and tested at the Istituto Nazionale di Geofisica (ING specifically addressed to seismic surveillance tasks, exploiting environmental monitoring, etc. It operates with an a scintillation technique (photomultiplier + Lucas Cell coupled with a water input system, that lets continuous dehumidified gas flow, stripped from groundwater under monitoring. Several laboratory tests have been carried out to check the stability and versatility of the system; moreover statistical tests have been accomplished on several data sets obtained with an 241Am radioactive standard source, to check stability of the photomultiplier. A customised water flow system has been developed to perform both the highest efficiency and lowest influence of external noise parameters. This new prototype is very cheap and will be integrated within the new multiparametric geochemical monitoring system GMS II, that is currently being developed at ING, specifically designed for geochemical surveillance of seismic events.

  17. Regional adaptive delaminating algorithm for rapid prototyping

    Institute of Scientific and Technical Information of China (English)

    CAI Daosheng; SHI Yusheng; HUANG Shuhuai

    2005-01-01

    With the development of rapid prototyping (RP) technology, the contradiction between fabricating speed and precision becomes more and more acute. In order to solve the contradiction, a regional effective adaptive delaminating algorithm is proposed in this paper. It is different from the traditional method that the regional adaptive delaminating method divides slicing contours into several regions and adaptively delaminates in respective region only according to the contours information. Namely, this method can not only adaptively delaminate at different height of CAD model but also adaptively delaminate different regions in one slicing layer. Furthermore, because the two-dimensional contour data adopted in this method are necessary for rapid prototyping system, this regional effective adaptive delaminating method is suitable for all RP systems. A comparative study is used to analyze the effectiveness of this method, which can demonstrate that this method can increase the fabricating speed and reduce the running cost under the condition of ensuring fabricating precision.

  18. SIMS Prototype System 4: design data brochure

    Energy Technology Data Exchange (ETDEWEB)

    1978-08-01

    A pre-package prototype unit is described having domestic hot water and room solar heating capability that uses air as the collector fluid. This system is designed to be used with a small single-family dwelling where a roof mounted collector array is not feasible. The prototype unit is an assembly containing 203 square feet of effective collector surface with 113 cubic feet of rock storage. The design of structure and storage is modular, which permits expansion and reduction of the collector array and storage bed in 68 square feet and 37 cubic feet increments respectively. The system is designed to be transportable. This permitted assembly and certification testing in one area and installation in another area without tear down and reassembly. Design, installation, operation, performance and maintenance of this system are described.

  19. Mechatronic Prototype of Parabolic Solar Tracker.

    Science.gov (United States)

    Morón, Carlos; Díaz, Jorge Pablo; Ferrández, Daniel; Ramos, Mari Paz

    2016-06-15

    In the last 30 years numerous attempts have been made to improve the efficiency of the parabolic collectors in the electric power production, although most of the studies have focused on the industrial production of thermoelectric power. This research focuses on the application of this concentrating solar thermal power in the unexplored field of building construction. To that end, a mechatronic prototype of a hybrid paraboloidal and cylindrical-parabolic tracker based on the Arduido technology has been designed. The prototype is able to measure meteorological data autonomously in order to quantify the energy potential of any location. In this way, it is possible to reliably model real commercial equipment behavior before its deployment in buildings and single family houses.

  20. Mechatronic Prototype of Parabolic Solar Tracker

    Directory of Open Access Journals (Sweden)

    Carlos Morón

    2016-06-01

    Full Text Available In the last 30 years numerous attempts have been made to improve the efficiency of the parabolic collectors in the electric power production, although most of the studies have focused on the industrial production of thermoelectric power. This research focuses on the application of this concentrating solar thermal power in the unexplored field of building construction. To that end, a mechatronic prototype of a hybrid paraboloidal and cylindrical-parabolic tracker based on the Arduido technology has been designed. The prototype is able to measure meteorological data autonomously in order to quantify the energy potential of any location. In this way, it is possible to reliably model real commercial equipment behavior before its deployment in buildings and single family houses.

  1. Prototype-based models in machine learning.

    Science.gov (United States)

    Biehl, Michael; Hammer, Barbara; Villmann, Thomas

    2016-01-01

    An overview is given of prototype-based models in machine learning. In this framework, observations, i.e., data, are stored in terms of typical representatives. Together with a suitable measure of similarity, the systems can be employed in the context of unsupervised and supervised analysis of potentially high-dimensional, complex datasets. We discuss basic schemes of competitive vector quantization as well as the so-called neural gas approach and Kohonen's topology-preserving self-organizing map. Supervised learning in prototype systems is exemplified in terms of learning vector quantization. Most frequently, the familiar Euclidean distance serves as a dissimilarity measure. We present extensions of the framework to nonstandard measures and give an introduction to the use of adaptive distances in relevance learning. PMID:26800334

  2. Laser prototyping of printed circuit boards

    Science.gov (United States)

    Nowak, M. R.; Antończak, A. J.; Kozioł, P. E.; Abramski, K. M.

    2013-09-01

    This paper describes the application of laser micromachining to rapid prototyping of printed circuit boards (PCB) using nano-second lasers: the solid-state Nd:YAG (532/1064 nm) laser and the Yb:glass fiber laser (1060 nm). Our investigations included tests for various mask types (synthetic lacquer, light-sensitive emulsion and tin). The purpose of these tests was to determine some of the basic parameters such as the resolution of PCB prototyping, speed of processing and quality of PCB mapping with commonly available laser systems. Optimization of process parameters and the proposed conversion algorithm have allowed us to produce circuit boards with a resolution similar to that of the Laser Direct Imaging (LDI) technology.

  3. Fermilab site-fillers as CAMEL prototypes

    International Nuclear Information System (INIS)

    At Snowmass, beam energies greater than about 10 TeV dominated the intellectual efforts related to hadron-hadron colliders. The anticipated cost and scope of these machines spurred the search for cost-cutting innovations and for a suitable site, perhaps in the southwestern desert. (Given its probable location and method of design, CAMEL seems an appropriate acronym for such a facility.) A prototype of more modest time-scale, cost, and energy is needed to bridge the physics gap until completion of CAMEL and to establish the feasibility of various proposed technologies. Building a prototype at Fermilab would reduce its cost, speed its completion, and improve its performance by taking advantage of existing real estate and expertise and by exploiting fully the potential capabilities of existing facilities (injectors, antiproton accumulator, etc.). The design and expected performance of various Fermilab site-filling (R = 2.4 km) antiproton-proton colliders are discussed. Other options are also described

  4. Powernext futuresTM back office user's guide

    International Nuclear Information System (INIS)

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing the French power exchange through an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-AheadTM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext FuturesTM since 18 June 2004. This document is the back office user's guide, it presents: the market model (specifications, regulation, legal framework), the members (traders, clearers, quotation providers, fees structure), the products (specifications, use, liquidity and market efficiency), the clearing (recording transactions, risk management before delivery period, last settlement of contracts, risk management during delivery, additional margin, examples, default management), the LCH.Clearnet Ltd clearing system (hardware and software requirements, setup of the VPN client software, functionalities, market information disclosure), the delivery (nomination, file characteristics and transmission), the payment (financial flows, eligible assets provided to cover margin requirements). ECS reports, treasury documents, contracts codification, FTP server arborescence, latent and carried-out margins and a glossary are given in the appendix. (J.S.)

  5. Orbitrap mass analyser for in situ characterisation of planetary environments: Performance evaluation of a laboratory prototype

    Science.gov (United States)

    Briois, Christelle; Thissen, Roland; Thirkell, Laurent; Aradj, Kenzi; Bouabdellah, Abdel; Boukrara, Amirouche; Carrasco, Nathalie; Chalumeau, Gilles; Chapelon, Olivier; Colin, Fabrice; Coll, Patrice; Cottin, Hervé; Engrand, Cécile; Grand, Noel; Lebreton, Jean-Pierre; Orthous-Daunay, François-Régis; Pennanech, Cyril; Szopa, Cyril; Vuitton, Véronique; Zapf, Pascal; Makarov, Alexander

    2016-10-01

    For decades of space exploration, mass spectrometry has proven to be a reliable instrumentation for the characterisation of the nature and energy of ionic and neutral, atomic and molecular species in the interplanetary medium and upper planetary atmospheres. It has been used as well to analyse the chemical composition of planetary and small bodies environments. The chemical complexity of these environments calls for the need to develop a new generation of mass spectrometers with significantly increased mass resolving power. The recently developed OrbitrapTM mass analyser at ultra-high resolution shows promising adaptability to space instrumentation, offering improved performances for in situ measurements. In this article, we report on our project named "Cosmorbitrap" aiming at demonstrating the adaptability of the Orbitrap technology for in situ space exploration. We present the prototype that was developed in the laboratory for demonstration of both technical feasibility and analytical capabilities. A set of samples containing elements with masses ranging from 9 to 208 u has been used to evaluate the performance of the analyser, in terms of mass resolving power (reaching 474,000 at m/z 9) and ability to discriminate between isobaric interferences, accuracy of mass measurement (below 15 ppm) and determination of relative isotopic abundances (below 5%) of various samples. We observe a good agreement between the results obtained with the prototype and those of a commercial instrument. As the background pressure is a key parameter for in situ exploration of atmosphere planetary bodies, we study the effect of background gas on the performanceof the Cosmorbitrap prototype, showing an upper limit for N2 in our set-up at 10-8 mbar. The results demonstrate the strong potential to adapt this technology to space exploration.

  6. Country prototypes and translation of health programs.

    Science.gov (United States)

    Sussman, Steve; Unger, Jennifer B; Palinkas, Lawrence A

    2008-06-01

    This article introduces the topic of international translation of health programs. Different perspectives toward the study of national-level variables that are relevant to translation of evidence-based programming developed outside of or in a country are discussed. Concepts including national prototypes, national stereotypes, country clusters, knowledge incompatibility, and absorptive capacity are introduced. The ideas expressed in this article serve to provide direction when considering developing a health behavior program for a country, using previous programmatic knowledge from elsewhere.

  7. Rapid Prototyping Technology of Tissue Engineering Scaffold

    Institute of Scientific and Technical Information of China (English)

    管金鹏

    2014-01-01

    In the modern medicine field, the transplant of organ and tissue is a big problem due to serious shortage of donor organ. Artificial organ and tissue is one of solutions. With the development of science, various tissue manufacture techniques emerged. Hereinto, due to its versatility both in materials and structure, rapid prototyping technology has become one of the important methods for tissue engineering scaffold fabrication in this field.

  8. Prototype ALICE front-end card

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    This circuit board is a prototype 48-channel front end digitizer card for the ALICE time projection chamber (TPC), which takes electrical signals from the wire sensors in the TPC and shapes the data before converting the analogue signal to digital data. A total of 4356 cards will be required to process the data from the ALICE TPC, the largest of this type of detector in the world.

  9. E-Commerce: Study, Development and Prototyping

    OpenAIRE

    Ing. María Lucía Rodríguez; Ing. M.Sc. Eustaquio Alcides Martínez Jara

    2016-01-01

    This project was a study of the development of an electronic commerce in Paraguay, tracking laws and regulatory decrees formulated by the technical agencies. As a result, a prototype is developed, which reproduces the steps to follow in a web-based e-commerce transaction using fictitious credit cards as payment method. A particular digital certificate created for testing purposes was used, performing secure connection via https protocol and the digital certificate issued by the En...

  10. Research of MMW radiometer virtual prototyping technology

    Institute of Scientific and Technical Information of China (English)

    Fan Qinghui; Li Xingguo; Zhang Guangfeng

    2008-01-01

    The idea of millimeter-wave (MMW) radiometer virtual prototyping is discussed in this paper. Designing en-vironment, designing method and the main modeling components of virtual MMW radiometer are researched. Important external parameters, which have significant influence to composing system, are used to components modeling, and then components are taken to buildup virtual MMW radiometer system. Moreover, the effect to output is contrasted whether there is a low-noise amplifier or not.

  11. Fast radio flashes observed with LOFAR prototypes

    OpenAIRE

    Nigl, A.

    2008-01-01

    This thesis consists of a detailed analysis of several observations with prototype stations of the Low Frequency Array (LOFAR). Chapter 1 introduces the field of radio astronomy, briefly describes the radio telescopes which were used and discusses radio frequency interference (RFI) and important tools for signal processing. Chapter 2 describes observations of Jupiter radio bursts, which were analyzed for propagation effects and cross-correlated with simultaneous observations of the Nançay Dec...

  12. DOE`s annealing prototype demonstration projects

    Energy Technology Data Exchange (ETDEWEB)

    Warren, J.; Nakos, J.; Rochau, G.

    1997-02-01

    One of the challenges U.S. utilities face in addressing technical issues associated with the aging of nuclear power plants is the long-term effect of plant operation on reactor pressure vessels (RPVs). As a nuclear plant operates, its RPV is exposed to neutrons. For certain plants, this neutron exposure can cause embrittlement of some of the RPV welds which can shorten the useful life of the RPV. This RPV embrittlement issue has the potential to affect the continued operation of a number of operating U.S. pressurized water reactor (PWR) plants. However, RPV material properties affected by long-term irradiation are recoverable through a thermal annealing treatment of the RPV. Although a dozen Russian-designed RPVs and several U.S. military vessels have been successfully annealed, U.S. utilities have stated that a successful annealing demonstration of a U.S. RPV is a prerequisite for annealing a licensed U.S. nuclear power plant. In May 1995, the Department of Energy`s Sandia National Laboratories awarded two cost-shared contracts to evaluate the feasibility of annealing U.S. licensed plants by conducting an anneal of an installed RPV using two different heating technologies. The contracts were awarded to the American Society of Mechanical Engineers (ASME) Center for Research and Technology Development (CRTD) and MPR Associates (MPR). The ASME team completed its annealing prototype demonstration in July 1996, using an indirect gas furnace at the uncompleted Public Service of Indiana`s Marble Hill nuclear power plant. The MPR team`s annealing prototype demonstration was scheduled to be completed in early 1997, using a direct heat electrical furnace at the uncompleted Consumers Power Company`s nuclear power plant at Midland, Michigan. This paper describes the Department`s annealing prototype demonstration goals and objectives; the tasks, deliverables, and results to date for each annealing prototype demonstration; and the remaining annealing technology challenges.

  13. AA Prototype-Quadrupole on Measurement Stand

    CERN Multimedia

    1979-01-01

    The very particular lattice of the AA required 2 types of quadrupoles: narrow ones (QFN, QDN) and wide ones (QFW, QDW). The wide ones, although rather short (steel length 0.54 m), had an unusually large aperture of 0.75 m in width, 0.68 m "good field". A prototype was built at CERN in 1978. Here we see it on its test stand, with a measurement coil inserted, Brian Pincott taking readings.

  14. Prototype storage cavity for LEP accelerating RF

    CERN Multimedia

    1980-01-01

    The principle of an RF storage cavity was demonstrated with this prototype, working at 500 MHz. Ian Wilso seems to hold it in his hands. The storage cavities had 4 portholes, 1 each for: RF feed; tuning; connection to the accelerating cavity; vacuum pump. The final storage cavities were larger, to suit the lower LEP accelerating frequency of 352.2 MHz. See also 8002294, 8006510X, 8109346, 8407619X, and Annual Report 1980, p.115.

  15. A Prototype Digital Image Management System

    OpenAIRE

    Dwyer, Samuel J.; Templeton, Arch W.; Anderson, William H.; Tarlton, Mark A.; Hensley, Kenneth S.; Lee, Kyo Rak; Batnitzky, Solomon; Rosenthal, Stanton J.; Johnson, Joy A.; Preston, David F.

    1983-01-01

    A prototype digital image management system has been designed, implemented and is being evaluated by our department. The system satisfies two major requirements: (a) an on-line access, rapid response microcomputer network providing 9 day archiving of digital data; (b) a long-term, low demand archiving system. This paper provides an estimate of the cost of the system, the potential cost-savings, and identifies the digital data throughput using the Ethernet communications protocol.

  16. Design of a fluid rotaryjoint prototype

    OpenAIRE

    Tänndal, Joakim

    2014-01-01

    This thesis, which has been carried out at the department of research and development at Cobham Antenna Systems, comprises the development of a fluid rotary joint (FRJ) prototype and shall provide a thorough insight in relevant design aspects. Based on input parameters and objectives derived from an actual Cobham project, the possibility of manufacturing a fluid rotary joint in-house has been investigated. A rotary joint is sub-system built up by modules linking signal transmission between th...

  17. AA Prototype-Quadrupole on Measurement Stand

    CERN Multimedia

    1978-01-01

    The very particular lattice of the AA required 2 types of quadrupoles: narrow ones (QFN, QDN) and wide ones (QFW, QDW). The wide ones, although not very long (steel length 0.54 m), had an unusually large aperture of 0.75 m in width, 0.68 m "good field". A prototype was built in 1978. Here we see it on its test stand, with Ray Brown positioning the measurement coil.

  18. A prototype of a high rating MRPC

    Institute of Scientific and Technical Information of China (English)

    WANG Yi; WANG Jing-Bo; YAN Qiang; LI Yuan-Jing; CHENG Jian-Ping; YUE Qian; LI Jin

    2009-01-01

    Six-gap resistive plate chamber (MRPC) prototypes with semiconductive glass electrodes (bulk resistivity~1010.cm) were studied for suitability in time-of-flight (TOF) applications at high rates. These studies were performed using a continuous electron beam of 800 MeV at IHEP and an X-ray machine. Time resolutions of about 100 ps and efficiencies larger than 90% were obtained for flux densities up to 28 kHz/cm2.

  19. Rapid prototyping technologies in prosthetic dentistry

    OpenAIRE

    YILDIRIM, Arş. Gör. Dt. Melike Pınar; BAYINDIR, Prof. Dr. Funda

    2013-01-01

    Emerged as the concept of rapid prototyping technology, nowadays, is seen as the future of quick and direct production. This technology found applications with metal framework of fixed partial dentures, framework of removable partial dentures, facial protheses and titanium implants in prosthetic dentistry. The virtual image of the restoration is tranferred to the computer and the laser beam is sintered the selected areas on the alloy powders and the restoration is produced layer by layer at s...

  20. Building a parabolic solar concentrator prototype

    Energy Technology Data Exchange (ETDEWEB)

    Escobar-Romero, J F M; Montiel, S Vazquez y; Granados-AgustIn, F; Rodriguez-Rivera, E; Martinez-Yanez, L [INAOE, Luis Enrique Erro 1, Tonantzintla, Pue., 72840 (Mexico); Cruz-Martinez, V M, E-mail: jfmescobar@yahoo.com [Universidad Tecnologica de la Mixteca, Camino a Acatilma Km 2.5, Huajuapan de Leon, Oax., 69000 (Mexico)

    2011-01-01

    In order to not further degrade the environment, people have been seeking to replace non-renewable natural resources such as fossil fuels by developing technologies that are based on renewable resources. An example of these technologies is solar energy. In this paper, we show the building and test of a solar parabolic concentrator as a prototype for the production of steam that can be coupled to a turbine to generate electricity or a steam engine in any particular industrial process.

  1. Vergleich zweier biologischer Herzklappen in Aortenposition: Carpentier-Edwards Perimount Magna EaseTM versus St. Jude Medical TrifectaTM

    OpenAIRE

    Fiegl, Kathrin

    2015-01-01

    Ziel dieser Studie war es das neue Konstruktionskonzept der St. Jude Medical TrifectaTM mit dem der CEPM EaseTM Bioprothese zu vergleichen. Dazu wurden hämodynamische und klinische Daten früh postoperativ und nach einem Jahr an einem gematchen Kollektiv mit jeweils 51 Patienten erhoben. Die SJM TrifectaTM zeigte niedrigere mittlere Druckgradienten früh postoperativ und nach einem Jahr, sowie höhere EOAs und EOAIs früh postoperativ. Es gab keine signifikanten Unterschiede im linksventrikulären...

  2. The AEI 10 m prototype interferometer

    Energy Technology Data Exchange (ETDEWEB)

    Gossler, S; Bertolini, A; Born, M; Dahl, K; Kranz, O; Lueck, H; Schnabel, R; Wanner, A; Westphal, T [Leibniz Universitaet Hannover, D-30167 Hannover (Germany); Chen, Y; Somiya, K [California Institute of Technology, Theoretical Astrophysics 130-33, Pasadena, CA 91125 (United States); Gering, D; Graef, C; Heinzel, G; Kawazoe, F; Kuehn, G; Mossavi, K; Taylor, J R [Albert-Einstein-Institut, Max-Planck-Institut fuer Gravitationsphysik, D-30167 Hannover (Germany); Hild, S; Strain, K A, E-mail: stefan.gossler@aei.mpg.d [University of Glasgow, Glasgow, G12 8QQ (United Kingdom)

    2010-04-21

    A 10 m prototype interferometer facility is currently being set up at the AEI in Hannover, Germany. The prototype interferometer will be housed inside a 100 m{sup 3} ultra-high vacuum envelope. Seismically isolated optical tables inside the vacuum system will be interferometrically interconnected via a suspension platform interferometer. Advanced isolation techniques will be used, such as inverted pendulums and geometrical anti-spring filters in combination with multiple-cascaded pendulum suspensions, containing an all-silica monolithic last stage. The light source is a 35 W Nd:YAG laser, geometrically filtered by passing it through a photonic crystal fibre and a rigid pre-modecleaner cavity. Laser frequency stabilisation will be achieved with the aid of a high finesse suspended reference cavity in conjunction with a molecular iodine reference. Coating thermal noise will be reduced by the use of Khalili cavities as compound end mirrors. Data acquisition and control of the experiments is based on the AdvLIGO digital control and data system. The aim of the project is to test advanced techniques for GEO 600 as well as to conduct experiments in macroscopic quantum mechanics. Reaching standard quantum-limit sensitivity for an interferometer with 100 g mirrors and subsequently breaching this limit, features most prominently among these experiments. In this paper we present the layout and current status of the AEI 10 m Prototype Interferometer project.

  3. A prototype piecewise-linear dynamic attenuator

    Science.gov (United States)

    Hsieh, Scott S.; Peng, Mark V.; May, Christopher A.; Shunhavanich, Picha; Fleischmann, Dominik; Pelc, Norbert J.

    2016-07-01

    The piecewise-linear dynamic attenuator has been proposed as a mechanism in CT scanning for personalizing the x-ray illumination on a patient- and application-specific basis. Previous simulations have shown benefits in image quality, scatter, and dose objectives. We report on the first prototype implementation. This prototype is reduced in scale and speed and is integrated into a tabletop CT system with a smaller field of view (25 cm) and longer scan time (42 s) compared to a clinical system. Stainless steel wedges were machined and affixed to linear actuators, which were in turn held secure by a frame built using rapid prototyping technologies. The actuators were computer-controlled, with characteristic noise of about 100 microns. Simulations suggest that in a clinical setting, the impact of actuator noise could lead to artifacts of only 1 HU. Ring artifacts were minimized by careful design of the wedges. A water beam hardening correction was applied and the scan was collimated to reduce scatter. We scanned a 16 cm water cylinder phantom as well as an anthropomorphic pediatric phantom. The artifacts present in reconstructed images are comparable to artifacts normally seen with this tabletop system. Compared to a flat-field reference scan, increased detectability at reduced dose is shown and streaking is reduced. Artifacts are modest in our images and further refinement is possible. Issues of mechanical speed and stability in the challenging clinical CT environment will be addressed in a future design.

  4. Prototyping Cognitive Prosthetics for People with Dementia

    Science.gov (United States)

    Davies, Richard; Nugent, Chris D.; Donnelly, Mark

    In the COGKNOW project, a cognitive prosthetic has been developed through the application of Information and Communication Technology (ICT)-based services to address the unmet needs and demands of persons with dementia. The primary aim of the developed solution was to offer guidance with conducting everyday activities for persons with dementia. To encourage a user-centred design process, a three-phased methodology was introduced to facilitate cyclical prototype development. At each phase, user input was used to guide the future development. As a prerequisite to the first phase of development, user requirements were gathered to identify a small set of functional requirements from which a number of services were identified. Following implementation of these initial services, the prototype was evaluated on a cohort of users and, through observing their experiences and recording their feedback, the design was refined and the prototype redeveloped to include a number of additional services in the second phase. The current chapter provides an overview of the services designed and developed in the first two phases.

  5. Sleeve Muscle Actuator: Concept and Prototype Demonstration

    Institute of Scientific and Technical Information of China (English)

    Tad Driver; Xiangrong Shen

    2013-01-01

    This paper presents the concept and prototype demonstration results of a new sleeve muscle actuator,which provides a significantly improved performance through a fundamental structural change to the traditional pneumatic muscle.Specifically,the sleeve muscle incorporates a cylindrical insert to the center of the pneumatic muscle,and thus eliminates the central portion of the intemal volume.Through the analysis of the actuation mechanism,it is shown that the sleeve muscle is able to provide a consistent increase of force capacity over the entire range of motion.Furthermore,the sleeve muscle provides a significant energy saving effect,as a result of the reduced internal volume as well as the enhance force capacity.To demonstrate this new concept,a sleeve muscle prototype was designed and fabricated.Experiments conducted on the prototype verified the improvement in the force capacity and demonstrated a significant energy saving effect (20%-37%).Finally,as the future work on this new concept,the paper presents a new robotic elbow design actuated with the proposed sleeve muscle.This unique design is expected to provide a highly compact and powerful actuation approach for robotic systems.

  6. Prototype of linac BLM at NSRL

    Science.gov (United States)

    Zeng, Ming; Li, Yuxiong; Gong, Guanghua; Li, Juexin; Shao, Beibei; Zhao, Zhengguo

    2007-08-01

    A prototype of the Beam Loss Monitoring (BLM) System for the linac and transportation line has been built up in National Synchrotron Radiation Laboratory. Different from the storage ring, the radiation field around linac and transportation line have a duty factor of 10 -6 and a dose rate of hundreds Gy/h. The Monte-Carlo calculation gave the dose, flux, energy and direction distributions of the radiation field. According to the simulation result, the proper type of detector was chosen and the installation positions were selected accordingly. The widely used ionization chamber is not suitable to give accurate and real-time information of beam loss due to its large dimension and slow respond speed. Several PIN silicon diode-based detectors were designed and tested, and a charge-balanced integrating amplifier circuit was applied to read out the charge. A distributed data acquisition system based on embedded Ethernet technology was implemented in the prototype, which can offer a web server from the microcontroller. From preliminary tests, this new prototype was proved to be sensitive to the change of the linac status, and is a useful tool for monitoring and adjusting machine parameters. Further analyses are required to achieve a more accurate measurement of the beam loss.

  7. ITER prototype fast plant system controller

    Energy Technology Data Exchange (ETDEWEB)

    Goncalves, B., E-mail: bruno@ipfn.ist.utl.pt [Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico, P-1049-001 Lisboa (Portugal); Sousa, J.; Carvalho, B.B.; Rodrigues, A.P.; Correia, M.; Batista, A. [Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico, P-1049-001 Lisboa (Portugal); Vega, J. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas, CIEMAT, Av. Complutense, Madrid (Spain); Ruiz, M.; Lopez, J.M. [Grupo de Investigacion en Instrumentacion y Acustica Aplicada, Universidad Politecnica de Madrid (Spain); Castro, R. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas, CIEMAT, Av. Complutense, Madrid (Spain); Wallander, A.; Utzel, N.; Makijarvi, P.; Simrock, S. [ITER Organization, CS 90 046, 13067 St. Paul lez Durance Cedex (France); Neto, A.; Alves, D.; Valcarcel, D.F. [Instituto de Plasmas e Fusao Nuclear - Laboratorio Associado, Instituto Superior Tecnico, P-1049-001 Lisboa (Portugal); Lousa, P.; Piedade, F.; Fernandes, L. [INOV, Lisbon (Portugal)

    2011-10-15

    ITER CODAC Design identified the need for slow and fast control plant systems, based respectively on industrial automation technology with maximum sampling rates below 100 Hz, and on embedded technology with higher sampling rates and more stringent real-time requirements. The fast system is applicable to diagnostics and plant systems in closed-control loops whose cycle times are below 1 ms. Fast controllers will be dedicated industrial controllers with the ability to supervise other fast and/or slow controllers, interface to actuators and sensors and high performance networks (HPN). This contribution presents the engineering design of two prototypes of a fast plant system controller (FPSC), specialized for data acquisition, constrained by ITER technological choices. This prototyping activity contributes to the Plant Control Design Handbook (PCDH) effort of standardization, specifically regarding fast controller characteristics. The prototypes will be built using two different form factors, PXIe and ATCA, with the aim of comparing the implementations. The presented solution took into consideration channel density, synchronization, resolution, sampling rates and the needs for signal conditioning such as filtering and galvanic isolation. The integration of the two controllers in the standard CODAC environment is also presented and discussed. Both controllers contain an EPICS IOC providing the interface to the mini-CODAC which will be used for all testing activities. The alpha version of the FPSC is also presented.

  8. SOT: A rapid prototype using TAE windows

    Science.gov (United States)

    Stephens, Mark; Eike, David; Harris, Elfrieda; Miller, Dana

    1986-01-01

    The development of the window interface extension feature of the Transportable Applications Executive (TAE) is discussed. This feature is being used to prototype a space station payload interface in order to demonstrate and assess the benefits of using windows on a bit mapped display and also to convey the concept of telescience, the control and operation of space station payloads from remote sites. The prototype version of the TAE with windows operates on a DEC VAXstation 100. This workstation has a high resolution 19 inch bit mapped display, a keyboard and a three-button mouse. The VAXstation 100 is not a stand-alone workstation, but is controlled by software executing on a VAX/8600. A short scenario was developed utilizing the Solar Optical Telescope (SOT) as an example payload. In the scenario the end-user station includes the VAXstation 100 plus an image analysis terminal used to display the CCD images. The layout and use of the prototype elements, i.e., the root menu, payload status window, and target acquisition menu is described.

  9. Prototype solar-heating system-engineering analysis

    Science.gov (United States)

    1978-01-01

    Space and domestic-water solar-heating prototype was tested in three phases: simulated energy function, winter normal operation, summer normal operation. Prototype was judged suitable for field installation.

  10. Prototype Theory Based Feature Representation for PolSAR Images

    OpenAIRE

    Huang Xiaojing; Yang Xiangli; Huang Pingping; Yang Wen

    2016-01-01

    This study presents a new feature representation approach for Polarimetric Synthetic Aperture Radar (PolSAR) image based on prototype theory. First, multiple prototype sets are generated using prototype theory. Then, regularized logistic regression is used to predict similarities between a test sample and each prototype set. Finally, the PolSAR image feature representation is obtained by ensemble projection. Experimental results of an unsupervised classification of PolSAR images show that our...

  11. Prototype system to manage data on coloproctology surgery

    OpenAIRE

    Huei Diana Lee; Wilson Jung; Adrieli Cristina da Silva; Luiz Henrique Dutra da Costa; Bianca Espindola; Cláudio saddy Rodrigues Coy; João José Fagundes; Feng Chung Wu

    2011-01-01

    OBJECTIVE: To develop a prototype system to manage data on coloproctology surgery, aiming at Data Quality (DQ) and the adoption of a DQ monitoring process, which is nonexistent in most biomedical systems. METHODS: The construction of the prototype was separated into five steps: analysis of an existing system (legacy), the analysis of requirements and specifications for the new prototype, the development of the model, definition of technologies and the development of a prototype. RESULTS: The ...

  12. Powernext futures{sup TM} back office user's guide; Powernext futures{sup TM} guide utilisateur compensation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-05-15

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing the French power exchange through an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead{sup TM} since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures{sup TM} since 18 June 2004. This document is the back office user's guide, it presents: the market model (specifications, regulation, legal framework), the members (traders, clearers, quotation providers, fees structure), the products (specifications, use, liquidity and market efficiency), the clearing (recording transactions, risk management before delivery period, last settlement of contracts, risk management during delivery, additional margin, examples, default management), the LCH.Clearnet Ltd clearing system (hardware and software requirements, setup of the VPN client software, functionalities, market information disclosure), the delivery (nomination, file characteristics and transmission), the payment (financial flows, eligible assets provided to cover margin requirements). ECS reports, treasury documents, contracts codification, FTP server arborescence, latent and carried-out margins and a glossary are given in the appendix. (J.S.)

  13. Atmospheric and land surface measurements in a prototype hydrologic observatory

    Science.gov (United States)

    Scanlon, B.; Krajewski, W.; Famiglietti, J.; Duffy, C.

    2003-12-01

    different microclimate, vegetation, land use, and soils regions to assess the relative importance of these parameters as controls on fluxes and to provide baseline data for predicting potential impacts of future climate and land use change on these fluxes. Critical parameters for hydrological modeling will be included in the measurement design. Although this prototype HO focuses on a porous media system in a humid environment, many of the design aspects are generic and should apply to HOs in other settings (fractured media, arid settings). Another goal of the program is to locate ground-based measurement stations to provide ground referencing for satellite systems. An example application is the use of satellite data (LandSat TM, AVHRR, and MODIS) to estimate ET with comparison to ground-based systems (Eddy Covariance/Bowen Ratio) and scintillometers. The use of Advanced Microwave Scanning Radiometer (AMSR-E) for monitoring soil moisture will also be evaluated using ground-based water content monitoring and field campaigns. Precipitation gauge clusters will be optimally located to evaluate NEXRAD and satellite precipitation data. Understanding the correlation between satellite and ground-based data is essential because spaceborne observations provide spatially and temporally distributed measurements and a framework for scaling local measurements to regional areas. The HO networks will provide valuable information on many aspects of the water cycle to advance our understanding on controls on spatial and temporal variability in fluxes across interfaces.

  14. 46 CFR 161.013-11 - Prototype test.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Prototype test. 161.013-11 Section 161.013-11 Shipping...: SPECIFICATIONS AND APPROVAL ELECTRICAL EQUIPMENT Electric Distress Light for Boats § 161.013-11 Prototype test. (a) Each manufacturer must test a prototype light identical to the lights to be certified prior...

  15. Prototypes as an Indirect Measure of Attitudes Toward Disability Groups

    Science.gov (United States)

    McCaughey, Tiffany J.; Strohmer, Douglas C.

    2005-01-01

    A prototype is an ongoing, cognitive representation of common attributes and distinct characteristics that define an object or person. This mixed-method study applies the robust concept of prototype to examine perceptions of disability groups. Core, secondary, and tertiary prototype characteristics are described for six disabilities:…

  16. Effect of Tm-Er concentration ratio on the photoluminescence of Er-Tm: Al2O3 thin films fabricated by pulsed laser deposition

    Institute of Scientific and Technical Information of China (English)

    Bo Zhou; Zhisong Xiao; Anping Huang; Lu Yan; Fang Zhu; Jinliang Wang; Penggang Yin; Hao Wang

    2008-01-01

    Er-Tm codoped amorphous aluminum oxide (a-Al2O3) thin films have been prepared by an alternative pulsed laser deposition. The phase structure and the surface of the deposited thin films were characterized by the X-ray diffraction (XRD) and scanning electron microscopy (SEM), respectively. Effective photoluminescence (PL) in the region of 350-900nm was observed when pumped at 325nm, and the PL performance has been improved by modifying the Tm3+ concentration. With the increasing of [Tm]/[Er] concentration ratio, the intensity of emission of 382nm and 500nm bands was improved effectively while that of 76Snm band increased smoothly. Our results suggest that the resonant energy transfer and cross relaxation between Tm3+ and Er3+ play an important role in the evolution of the luminescent response.

  17. Thermoelectric Properties of Pseudogap Ti10Ru19B8 and Ti9TM2Ru18B8 (TM: Cr-Cu) Compounds

    Science.gov (United States)

    Takagiwa, Y.; Yoshida, T.; Yanagihara, D.; Kimura, K.

    2015-06-01

    The thermoelectric properties of ternary Ti10Ru19B8 and quaternary Ti9TM2Ru18B8 (TM: Cr, Mn, Fe, Co, Ni, Cu) compounds were investigated in the temperature range from 373 K to 973 K. They form pseudogaps in the electronic densities of states near the Fermi level, E F, which is suitable for thermoelectric materials. We synthesized crack-free pellet samples using arc-melting followed by spark plasma sintering. A maximum dimensionless figure of merit zT max was 0.09 at 973 K for Ti10Ru19B8 whereas a large power factor of 1.4 mW/m K2 was obtained at that temperature. The phonon thermal conductivity decreased through TM substitutions; however, the power factor also decreased due to an additional electronic density of states originated from TM d-states around E F; that is, excitations of both holes and electrons.

  18. SCF{sup TM}, Single Column Floater - a deepwater solution

    Energy Technology Data Exchange (ETDEWEB)

    Basak, Jayanto K.; Denman, Jeremy [ABB Lummus Global Inc., Duque de Caxias, RJ (Brazil). Deepwater Technology and Engineering

    2004-07-01

    As commercially attractive oil and gas discoveries are found in ever increasing water depths, the associated technical, operational and economic challenges become formidable. Appropriate selection of development architecture is essential for the overall success of a project. To properly address this wide range of development options, ABB has developed a portfolio of various hull forms. The SCF{sup TM} concept is one such hull form for a deep water solution. This paper presents the development of the SCF platform by addressing design issues, model test, product storage, fabrication, quay side integration, transportation, installation, schedule and cost estimate. The SCF concept brings tangible benefits to many of the deep water developments around the globe. The attributes of the SCF concept can commercially benefit deep water developments in Brazil as well as potentially generate in-country fabrication and service opportunities. (author)

  19. Leanergy(TM): how lean manufacturing can improve energy efficiency.

    Science.gov (United States)

    Riche, Jean-Pierre

    2013-01-01

    Energy efficiency has become a competitive issue for industrial companies. The evolution of energy prices and regulation will make this issue even more important in the future. For several years, the energy-intensive chemical industry has been implementing corrective actions. Helped by the absorption of base load energy consumption by larger production volumes, specific energy consumption (KWh per production unit) has been significantly reduced in recent years. However, most plants have reached the end of their first action plan based on improving the utilities performance. The Leanergy(TM) method developed by the consultancy company Okavango-energy, is a structured approach based on lean manufacturing which widens the scope of saving sources to process and operations. Starting from the analysis of actual production requirements, Okavango is able to adjust consumption to minimum requirements and so remove any energy consumption that does not contribute to the added value creation. PMID:24388133

  20. Intubation with Airtraq TM laryngoscope in a morbidly obese patient

    Directory of Open Access Journals (Sweden)

    Pratik Tantia

    2011-01-01

    Full Text Available In the present study, we report a case of successful endotracheal intubation using Airtraq TM Laryngoscope (AQL in a morbidly obese patient. A 35-year-old woman, morbidly obese (weight, 105 kg; height, 160 cm; BMI, 41 kg/m 2 , known hypertensive and diabetic, was admitted in the operating room for total abdominal hysterectomy under general anesthesia. The preoperative airway assessment anticipated both difficult bag-mask ventilation and intubation. Tracheal intubation using AQL was attempted after induction with propofol and relaxation with succinylcholine. Successful tracheal intubation was accomplished within 12 seconds of insertion of AQL into the oral cavity. The minimal hemodynamic response during this maneuver was advantageous in our patient.

  1. Dielectric multilayer waveguides for TE and TM mode matching

    CERN Document Server

    Shyroki, D M; Shyroki, Dzmitry M.; Lavrinenko, Andrei V.

    2003-01-01

    We analyse theoretically for the first time to our knowledge the perfect phase matching of guided TE and TM modes with a multilayer waveguide composed of linear isotropic dielectric materials. Alongside strict investigation into dispersion relations for multilayer systems, we give an explicit qualitative explanation for the phenomenon of mode matching on the basis of the standard one-dimensional homogenization technique, and discuss the minimum number of layers and the refractive index profile for the proposed device scheme. Direct applications of the scheme include polarization-insensitive, intermodal dispersion-free planar propagation, efficient fibre-to-planar waveguide coupling and, potentially, mode filtering. As a self-sufficient result, we present compact analytical expressions for the mode dispersion in a finite, N-period, three-layer dielectric superlattice.

  2. Leanergy(TM): how lean manufacturing can improve energy efficiency.

    Science.gov (United States)

    Riche, Jean-Pierre

    2013-01-01

    Energy efficiency has become a competitive issue for industrial companies. The evolution of energy prices and regulation will make this issue even more important in the future. For several years, the energy-intensive chemical industry has been implementing corrective actions. Helped by the absorption of base load energy consumption by larger production volumes, specific energy consumption (KWh per production unit) has been significantly reduced in recent years. However, most plants have reached the end of their first action plan based on improving the utilities performance. The Leanergy(TM) method developed by the consultancy company Okavango-energy, is a structured approach based on lean manufacturing which widens the scope of saving sources to process and operations. Starting from the analysis of actual production requirements, Okavango is able to adjust consumption to minimum requirements and so remove any energy consumption that does not contribute to the added value creation.

  3. Satellite image classification methods and Landsat 5TM bands

    CERN Document Server

    Tamouk, Jamshid; Farmanbar, Mina

    2013-01-01

    This paper attempts to find the most accurate classification method among parallelepiped, minimum distance and chain methods. Moreover, this study also challenges to find the suitable combination of bands, which can lead to better results in case combinations of bands occur. After comparing these three methods, the chain method over perform the other methods with 79% overall accuracy. Hence, it is more accurate than minimum distance with 67% and parallelepiped with 65%. On the other hand, based on bands features, and also by combining several researchers' findings, a table was created which includes the main objects on the land and the suitable combination of the bands for accurately detecting of landcover objects. During this process, it was observed that band 4 (out of 7 bands of Landsat 5TM) is the band, which can be used for increasing the accuracy of the combined bands in detecting objects on the land.

  4. Corrosion behavior of alloy M5TM: experience feedback

    International Nuclear Information System (INIS)

    M5TMis the reference alloy developed by AREVA NP to meet all the demands of today's nuclear market. The excellent corrosion behavior is now clearly demonstrated in a wide range of environment and plant operations ands deeply analyzed up to 7 cycles and a burn up of nearly 80 GWd/tHM. Thus, M5TMis also a good candidate for structure components (guide tube and grid). The corrosion behavior of claddings or guide tube and grids are compared and appears as equivalent. To date he primary water chemistry evolutions (high Li or Zn addition) have no influence on the corrosion of M5TM. Then M5TMpresents all the guarantees to answer to high duty and high burn up demands

  5. Explicit TE/TM scheme for particle beam simulations

    Energy Technology Data Exchange (ETDEWEB)

    Dohlus, M.; Zagorodnov, I.

    2008-10-15

    In this paper we propose an explicit two-level conservative scheme based on a TE/TM like splitting of the field components in time. Its dispersion properties are adjusted to accelerator problems. It is simpler and faster than the implicit version. It does not have dispersion in the longitudinal direction and the dispersion properties in the transversal plane are improved. The explicit character of the new scheme allows a uniformly stable conformal method without iterations and the scheme can be parallelized easily. It assures energy and charge conservation. A version of this explicit scheme for rotationally symmetric structures is free from the progressive time step reducing for higher order azimuthal modes as it takes place for Yee's explicit method used in the most popular electrodynamics codes. (orig.)

  6. Blue and white light emission in Tm3+ and Tm3+/Dy3+ doped zinc phosphate glasses upon UV light excitation

    Science.gov (United States)

    Meza-Rocha, A. N.; Speghini, A.; Lozada-Morales, R.; Caldiño, U.

    2016-08-01

    A spectroscopic study based on photoluminescence spectra and decay time profiles in Tm3+ and Tm3+/Dy3+ doped Zn(PO3)2 glasses is reported. The Tm3+ doped Zn(PO3)2 glass, upon 357 nm excitation, exhibits blue emission with CIE1931 chromaticity coordinates, x = 0.157 and y = 0.030, and color purity of about 96%. Under excitations at 348, 352 and 363 nm, which match with the emissions of AlGaN and GaN based LEDs, the Tm3+/Dy3+ co-doped Zn(PO3)2 glass displays natural white, bluish white and cool white overall emissions, with correlated color temperature values of 4523, 10700 and 7788 K, respectively, depending strongly on the excitation wavelength. The shortening of the Dy3+ emission decay time in presence of Tm3+ suggests that Dy3+→Tm3+ non-radiative energy transfer occurs. By using the Inokuti-Hirayama model, it is inferred that an electric quadrupole-quadrupole interaction might be the dominant mechanism involved in the energy transfer. The efficiency and probability of this energy transfer are 0.12 and 126.70 s-1, respectively.

  7. Electrostatic self-assembly Pd particles on NafionTM membrane surface to reduce methanol crossover

    Institute of Scientific and Technical Information of China (English)

    TANG Haolin; PAN Mu; MU Shichun; YUAN Runzhang

    2005-01-01

    @@ NafionTM perfluorosulfonate proton exchange membranes (PEM) have been widely used as solid electrolytes in direct methanol fuel cell (DMFC) because it possesses relatively good mechanical strength and chemical stability. Due to its structure of side chains fixed at CF backbones, phase separation occurs between hydrophilic regions and hydrophobic ones in hydrated NafionTM membrane[1].

  8. Seroepidemiology of TmPV1 infection in captive and wild Florida manatees (Trichechus manatus latirostris).

    Science.gov (United States)

    Donà, Maria Gabriella; Rehtanz, Manuela; Adimey, Nicole M; Bossart, Gregory D; Jenson, Alfred B; Bonde, Robert K; Ghim, Shin-je

    2011-07-01

    In 1997, cutaneous papillomatosis caused by Florida manatee (Trichechus manatus latirostris [Tm]) papillomavirus 1 (TmPV1) was detected in seven captive manatees at the Homosassa Springs Wildlife State Park, Florida, USA, and, subsequently, in two wild manatees from the adjacent Homosassa River. Since then, papillomatosis has been reported in captive manatees housed in other locations, but not in wild animals. To determine TmPV1 antibody prevalence in captive and wild manatees sampled at various locations throughout Florida coastal regions, virus-like particles, composed of the L1 capsid protein of TmPV1, were generated with a baculovirus expression system and used to measure anti-TmPV1 antibodies in an enzyme-linked immunosorbent assay. Serologic analysis of 156 manatees revealed a TmPV1 antibody prevalence of 26.3%, with no significant difference between captive (n=39) and wild (n=117) manatees (28.2% and 25.6%, respectively). No antibody-positive wild animal showed PV-induced cutaneous lesions, whereas papillomatosis was observed in 72.7% of antibody-positive captive manatees. Our data indicate that Florida manatees living in the wild are naturally infected by TmPV1 but rarely show TmPV1-induced papillomatosis. Hence, it appears that the wild population would not be harmed in a case of contact with captive animals without visible lesions and productive infections, which could be thus released into the wild. PMID:21719832

  9. Seroepidemiology of TmPV1 infection in captive and wild Florida manatees (Trichechus manatus latirostris)

    Science.gov (United States)

    Dona, Maria Gabriella; Rehtanz, Manuela; Adimey, Nicole M.; Bossart, Gregory D.; Jenson, Alfred B.; Bonde, Robert K.; Ghim, Shin-je

    2011-01-01

    In 1997, cutaneous papillomatosis caused by Florida manatee (Trichechus manatus latirostris [Tm]) papillomavirus 1 (TmPV1) was detected in seven captive manatees at the Homosassa Springs Wildlife State Park, Florida, USA, and, subsequently, in two wild manatees from the adjacent Homosassa River. Since then, papillomatosis has been reported in captive manatees housed in other locations, but not in wild animals. To determine TmPV1 antibody prevalence in captive and wild manatees sampled at various locations throughout Florida coastal regions, virus-like particles, composed of the L1 capsid protein of TmPV1, were generated with a baculovirus expression system and used to measure anti-TmPV1 antibodies in an enzyme-linked immunosorbent assay. Serologic analysis of 156 manatees revealed a TmPV1 antibody prevalence of 26.3%, with no significant difference between captive (n=39) and wild (n=117) manatees (28.2% and 25.6%, respectively). No antibody-positive wild animal showed PV-induced cutaneous lesions, whereas papillomatosis was observed in 72.7% of antibody-positive captive manatees. Our data indicate that Florida manatees living in the wild are naturally infected by TmPV1 but rarely show TmPV1-induced papillomatosis. Hence, it appears that the wild population would not be harmed in a case of contact with captive animals without visible lesions and productive infections, which could be thus released into the wild.

  10. Seroepidemiology of TmPV1 infection in captive and wild Florida manatees (Trichechus manatus latirostris).

    Science.gov (United States)

    Donà, Maria Gabriella; Rehtanz, Manuela; Adimey, Nicole M; Bossart, Gregory D; Jenson, Alfred B; Bonde, Robert K; Ghim, Shin-je

    2011-07-01

    In 1997, cutaneous papillomatosis caused by Florida manatee (Trichechus manatus latirostris [Tm]) papillomavirus 1 (TmPV1) was detected in seven captive manatees at the Homosassa Springs Wildlife State Park, Florida, USA, and, subsequently, in two wild manatees from the adjacent Homosassa River. Since then, papillomatosis has been reported in captive manatees housed in other locations, but not in wild animals. To determine TmPV1 antibody prevalence in captive and wild manatees sampled at various locations throughout Florida coastal regions, virus-like particles, composed of the L1 capsid protein of TmPV1, were generated with a baculovirus expression system and used to measure anti-TmPV1 antibodies in an enzyme-linked immunosorbent assay. Serologic analysis of 156 manatees revealed a TmPV1 antibody prevalence of 26.3%, with no significant difference between captive (n=39) and wild (n=117) manatees (28.2% and 25.6%, respectively). No antibody-positive wild animal showed PV-induced cutaneous lesions, whereas papillomatosis was observed in 72.7% of antibody-positive captive manatees. Our data indicate that Florida manatees living in the wild are naturally infected by TmPV1 but rarely show TmPV1-induced papillomatosis. Hence, it appears that the wild population would not be harmed in a case of contact with captive animals without visible lesions and productive infections, which could be thus released into the wild.

  11. The equivalence between the TE,TM model and the Darwin models

    Institute of Scientific and Technical Information of China (English)

    YING; LungAn

    2010-01-01

    In this paper,we study the TE,TM model by using the decompositions of the vector fields in 2-D bounded multiply connected domains and 2-D unbounded domains,respectively.We find that the TE,TM model and the Darwin models are equivalent if we assume some regularity of the initial data.

  12. The role of transmembrane segment II in 7TM receptor activation

    DEFF Research Database (Denmark)

    Benned-Jensen, Tau; Rosenkilde, M M

    2009-01-01

    , accumulating evidence emphasize that this is not the case. In this review, we focus on TM-II with an emphasis on position II:20/2.60, and present data from structure-activity studies on a range of Family A 7TM receptors including chemokine, ghrelin and melanocortin receptors in addition to the orphan EBI2...

  13. iPad[TM]: Enhancing Learning & Communication for Students with Special Needs

    Science.gov (United States)

    Friedlander, Brian; Besko-Maughan, Christine

    2011-01-01

    The iPad[TM] is a revolutionary technology for use in our 21st century classrooms. It is profoundly changing both the manner in which teachers present instructional content, as well as the way students process and learn new information. The multi-sensory design of the iPad[TM] makes it an ideal tool for teaching students with special needs. This…

  14. 78 FR 57149 - Western Minnesota Municipal Power Agency, Lock+TM

    Science.gov (United States)

    2013-09-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Western Minnesota Municipal Power Agency, Lock+ TM Hydro Friends Fund III... Agency (Western Minnesota) and Lock+ TM Hydro Friends Fund III, LLC (Hydro Friends) filed...

  15. Does LibQUAL+[TM] Account for Student Loyalty to a University College Library?

    Science.gov (United States)

    Helgesen, Oyvind; Nesset, Erik

    2011-01-01

    Purpose: The purpose of this paper is to find out whether LibQUAL+[TM]can account for student loyalty to the library of an institution of higher education. LibQUAL+[TM] is a marketing tool that is used to measure perceived service quality of libraries, and the present analysis aims at validating this service quality instrument within a more…

  16. Rapid detection of Salmonella in foods using a combination of SPRINT TM,MSRV TM and Salmonella Latex TestTM Detecção rápida de Salmonella em alimentos empregando uma combinação de SPRINT®, MSRV® e Salmonella Latex Test®

    OpenAIRE

    Jane Maria Lafayette Neves Gelinski; Gunnar Martin; Maria Teresa Destro; Mariza Landgraf; Bernadette Dora Gombossy de Melo Franco

    2002-01-01

    A new procedure for rapid detection of Salmonella in foods, based on the combination of SPRINT TM, MSRV TM and Salmonella Latex TestTM, was evaluated. SPRINT TM is a system to reduce the preenrichment and selective enrichment steps to 24 hours. MSRV TM is a semi-solid selective media for detection of motile Salmonella. Salmonella Latex TestTM is a rapid latex agglutination test for Salmonella. Using the three systems in combination, the total time for detection of Salmonella in a food sample ...

  17. The Space House TM : Space Technologies in Architectural Design

    Science.gov (United States)

    Gampe, F.; Raitt, D.

    2002-01-01

    The word "space" has always been associated with and had a profound impact upon architectural design. Until relatively recently, however, the term has been used in a different sense to that understood by the aerospace community - for them, space was less abstract, more concrete and used in the context of space flight and space exploration, rather than, say, an empty area or space requiring to be filled by furniture. However, the two senses of the word space have now converged to some extent. Interior designers and architects have been involved in designing the interior of Skylab, the structure of the International Space Station, and futuristic space hotels. Today, architects are designing, and builders are building, houses, offices and other structures which incorporate a plethora of new technologies, materials and production processes in an effort not only to introduce innovative and adventurous ideas but also in an attempt to address environmental and social issues. Foremost among these new technologies and materials being considered today are those that have been developed for and by the space industry. This paper examines some of these space technologies, such as energy efficient solar cells, durable plastics, air and water filtration techniques, which have been adapted to both provide power while reducing energy consumption, conserve resources and so on. Several of these technologies have now been employed by the European Space Agency to develop a Space House TM - the first of its kind, which will be deployed not so much on planets like Mars, but rather here on Earth. The Space House TM, which exhibits many innovative features such as high strength light-weight carbon composites, active noise-damped, (glass and plastic) windows, low-cost solar arrays and latent heat storage, air and water purification systems will be described.

  18. Efficient High Power Ho,Tm:GdVO4 Laser

    Institute of Scientific and Technical Information of China (English)

    WANG Yue-Zhu; ZHU Guo-Li; JU You-Lun; YAO Bao-Quan

    2011-01-01

    We report a 22.3 W cw diode-pumped cryogenic Ho(0.5at. %), Tm(at.5%):GdVC>4 laser at a wavelength of 2.05 fzm. It is pumped by two fiber-coupled laser diodes with a fiber core diameter of 0.4 mm, both of which provide 42 W pump power near 802 nm. A cw output power of 22.3 W was obtained at the pump power of 51.0 W, corresponding to an optical-to-optical conversion efficiency of 43.7% when the ratio of the pump beam to oscillating laser beam in the crystal was ^1.33:1. The M2 factor was found to be 2.0 under an output power of 16.5 W.%@@ We report a 22.3 W ew diode-pumped cryogenic Ho(0.5at.%),Tm(at.5%):GdVO4 laser at a wavelength of 2.05μm.It is pumped by two fiber-coupled laser diodes with a fiber core diameter of 0.4 mm,both of which provide 42W pump power near 802 nm.A cw output power of 22.3 W was obtained at the pump power of 51.0W,corresponding to an optical-to-optical conversion efficiency of 43.7%when the ratio of the pump beam to oscillating laser beam in the crystal was ~1.33:1.The M2 factor was found to be 2.0 under an output power of 16.5 W.

  19. Mobile robot prototype detector of gamma radiation

    International Nuclear Information System (INIS)

    In this paper the technological development of a mobile robot prototype detector of gamma radiation is shown. This prototype has been developed for the purpose of algorithms implementation for the applications of terrestrial radiation monitoring of exposed sources, search for missing radioactive sources, identification and delineation of radioactive contamination areas and distribution maps generating of radioactive exposure. Mobile robot detector of radiation is an experimental technology development platform to operate in laboratory environment or flat floor facilities. The prototype integrates a driving section of differential configuration robot on wheels, a support mechanism and rotation of shielded detector, actuator controller cards, acquisition and processing of sensor data, detection algorithms programming and control actuators, data recording (Data Logger) and data transmission in wireless way. The robot in this first phase is remotely operated in wireless way with a range of approximately 150 m line of sight and can extend that range to 300 m or more with the use of signal repeaters. The gamma radiation detection is performed using a Geiger detector shielded. Scan detection is performed at various time sampling periods and diverse positions of discrete or continuous angular orientation on the horizon. The captured data are geographical coordinates of robot GPS (latitude and longitude), orientation angle of shield, counting by sampling time, date, hours, minutes and seconds. The data is saved in a file in the Micro Sd memory on the robot. They are also sent in wireless way by an X Bee card to a remote station that receives for their online monitoring on a laptop through an acquisition program by serial port on Mat Lab. Additionally a voice synthesizing card with a horn, both in the robot, periodically pronounced in Spanish, data length, latitude, orientation angle of shield and detected accounts. (Author)

  20. E-Commerce: Study, Development and Prototyping

    Directory of Open Access Journals (Sweden)

    Ing. María Lucía Rodríguez

    2016-06-01

    Full Text Available This project was a study of the development of an electronic commerce in Paraguay, tracking laws and regulatory decrees formulated by the technical agencies. As a result, a prototype is developed, which reproduces the steps to follow in a web-based e-commerce transaction using fictitious credit cards as payment method. A particular digital certificate created for testing purposes was used, performing secure connection via https protocol and the digital certificate issued by the Enforcement Authority and the Ministry of Industry and Trade. The results were obtained through the measurement of the database log, matching planned rules for transactions with the results obtained.

  1. Prototype steel-concrete LEP dipole magnet

    CERN Multimedia

    1981-01-01

    The magnetic field needed in the LEP dipole magnets was rather low, of a fraction of tesla. This lead to the conception of a novel yoke structure consisting of stacks of 1.5 mm thick low-carbon steel laminations spaced by 4.1 mm with the spaces filled with concrete. The excitation coils were also very simple: aluminium bars insulated by polyester boxes in this prototype, by glass-epoxy in the final magnets. For details see LEP-Note 118,1978 and LEP-Note 233 1980. See also 8111529,7908528X.

  2. Prototyping of the ILC Baseline Positron Target

    Energy Technology Data Exchange (ETDEWEB)

    Gronberg, J; Brooksby, C; Piggott, T; Abbott, R; Javedani, J; Cook, E

    2012-02-29

    The ILC positron system uses novel helical undulators to create a powerful photon beam from the main electron beam. This beam is passed through a titanium target to convert it into electron-positron pairs. The target is constructed as a 1 m diameter wheel spinning at 2000 RPM to smear the 1 ms ILC pulse train over 10 cm. A pulsed flux concentrating magnet is used to increase the positron capture efficiency. It is cooled to liquid nitrogen temperatures to maximize the flatness of the magnetic field over the 1 ms ILC pulse train. We report on prototyping effort on this system.

  3. Prototyping of the ILC Baseline Positron Target

    CERN Document Server

    Gronberg, Jeff; Piggott, Tom; Abbott, Ryan; Javedani, Jay; Cook, Ed

    2012-01-01

    The ILC positron system uses novel helical undulators to create a powerful photon beam from the main electron beam. This beam is passed through a titanium target to convert it into electron-positron pairs. The target is constructed as a 1 m diameter wheel spinning at 2000 RPM to smear the 1 ms ILC pulse train over 10 cm. A pulsed flux concentrating magnet is used to increase the positron capture efficiency. It is cooled to liquid nitrogen temperatures to maximize the flatness of the magnetic field over the 1 ms ILC pulse train. We report on prototyping effort on this system.

  4. Prototype dining hall energy efficiency study

    Energy Technology Data Exchange (ETDEWEB)

    Mazzucchi, R.P.; Bailey, S.A.; Zimmerman, P.W.

    1988-06-01

    The energy consumption of food service facilities is among the highest of any commercial building type, owing to the special requirements for food preparation, sanitation, and ventilation. Consequently, the US Air Force Engineering and Services Center (AFESC) contracted with Pacific Northwest Laboratory (PNL) to collect and analyze end-use energy consumption data for a prototypical dining hall and make specific recommendations on cost-effective energy conservation options. This information will be used to establish or update criteria for dining hall designs and retrofits as appropriate. 6 refs., 21 figs., 23 tabs.

  5. E-Commerce: Study, Development and Prototyping

    Directory of Open Access Journals (Sweden)

    Ing. María Lucía Rodríguez

    2016-02-01

    Full Text Available This project was a study of the development of an electronic commerce in Paraguay, tracking laws and regulatory decrees formulated by the technical agencies. As a result, a prototype is developed, which reproduces the steps to follow in a web-based e-commerce transaction using fictitious credit cards as payment method. A particular digital certificate created for testing purposes was used, performing secure connection via https protocol and the digital certificate issued by the Enforcement Authority and the Ministry of Industry and Trade. The results were obtained through the measurement of the database log, matching planned rules for transactions with the results obtained.

  6. A prototype ionization profile monitor for RHIC

    Energy Technology Data Exchange (ETDEWEB)

    Connolly, R.; Cameron, P.; Ryan, W. [and others

    1997-07-01

    Transverse beam profiles in the Relativistic Heavy-Ion Collider (RHIC) will be measured with ionization profile monitors (IPM`s). Each IPM collects and measures the distribution of electrons in the beamline resulting from residual gas ionization during bunch passage. The electrons are swept transversely from the beamline and collected on strip anodes oriented parallel to the beam axis. At each bunch passage the charge pulses are amplified, integrated, and digitized for display as a profile histogram. A prototype detector was tested in the injection line during the RHIC Sextant Test. This paper describes the detector and gives results from the beam tests.

  7. SONG - getting ready for the prototype

    International Nuclear Information System (INIS)

    The Stellar Observations Network Group, SONG, is a project which aims at building a network of eight identical telescopes distributed geographically around the globe to allow long-term, high-duty-cycle observations of stellar oscillations and to search for exoplanets via the microlensing technique. At each of the network nodes a 1 m telescope with a high-resolution spectrograph and two lucky-imaging cameras is placed. The instruments and telescope, for the prototype node, are currently being built and installation at Observatorio del Teide, Tenerife, Spain is foreseen for early 2011.

  8. Test of the ZEUS forward calorimeter prototype

    International Nuclear Information System (INIS)

    Four prototype modules following the same design as the ZEUS forward calorimeter (FCAL) modules have been constructed and tested with electrons, hadrons and muons in the momentum range of 1 to 100 GeV/c. The main topics under investigation were: calibration, uniformity of response, noise, light yield, energy resolution and the electron to hadron response (e/h ratio). The result of the measurements is presented and the expected performance of the FCAL is discussed in the light of these results. (orig.)

  9. 值得升级吗?TM2008 Beta新版评测

    Institute of Scientific and Technical Information of China (English)

    第七乐章(文/图)

    2008-01-01

    在经过四个预览版本的测试之后,TM终于正式发布新版TM2008 Beta。如果说TM2008之前的预览版本新变化更多的只是在外观界面上,那么此番的TM2008 Beta则是将亮点转移到功能方面。TM2008 Beta除了延续了全新的外观界面,添加了许多原本缺少的功能。下面,就让我们来看看TM2008 Beta中有哪些新功能,它们是否能让我们喜欢呢?

  10. Upconversion energy transfer in Yb3+/Tm3+ doped tellurite glass

    Science.gov (United States)

    Żmojda, J.; Dorosz, D.; Kochanowicz, M.; Dorosz, J.

    2011-06-01

    The paper presents energy transfer in tellurite glass from the system TeO2 - GeO2 - PbO - PbF2- BaO - Nb2O5 - LaF3 doped with Yb3+/Tm3+ ions. Under the excitation of 976 nm laser a strong blue emission (477 nm) corresponding to the transition 1G4 --> 3H6 in thulium ions was observed. Analysing the influence of the content of Tm3+ ions on the level of luminescence obtained by the mechanism of upconversion it was established that the most effective energy transfer between Yb 3+--> Tm3+ ions took place in the matrix doped in the following proportion: 1 Yb3+:0.1 Tm3+ (%mol). Based on the non-resonant process of energy transfer between Yb3+ and Tm3+ ions the mechanism of upconversion was discussed.

  11. 75 FR 5071 - Mississippi L&D 21, LLC, Mississippi River No. 21 Hydropower Company Lock + TM

    Science.gov (United States)

    2010-02-01

    ... + \\TM\\ Hydro Friends Fund XXXII, LLC; Notice of Preliminary Permit Applications Accepted for Filing and... proposed Mississippi River No. 21 Hydropower Project No. 13637. On January 8, 2010, Lock + TM Hydro...

  12. Shear sensitive silicon piezoresistive tactile sensor prototype

    Science.gov (United States)

    Wang, Lin; Beebe, David J.

    1998-09-01

    Shear sensing ability it important in many fields such as robotics, rehabilitation, teleoperation and human computer interfaces. A shear sensitive tactile sensor prototype is developed based on the principles of the piezoresistive effect in silicon, and using microfabrication technology. Analogous to the conventional silicon piezoresistive pressure sensor, piezoresistive resistors embedded in a silicon diaphragm are used to sense stress change. An additional mesa is fabricated on the top of the diaphragm and serves to transform an applied force to a stress. Both the shear and normal components of the force are resolved by measuring the resistance changes of the four resistors placed at the corners of a prism mesa. The prototype is tested both statically and dynamically when a spatial force of 0 - 300 gram is applied. Good linearity (R > 0.98) and high repeatability are observed. In this paper, the force sensing mechanism and force determination approach are described. The fabrication process is presented. The preliminary testing results are presented and discussed.

  13. Experimental prototype of an electric elevator

    Science.gov (United States)

    Gaiceanu, M.; Epure, S.; Ciuta, S.

    2016-08-01

    The main objective is to achieve an elevator prototype powered by a three-phase voltage system via a bidirectional static power converter ac-ac with regenerating capability. In order to diminish the power size of the electric motor up to 1/3 of rated power, the elevator contains two carriages of the same weight, one serving as the payload, and the other as counterweight. Before proper operation of the static power converter, the capacitor must be charged at rated voltage via a precharge circuit. At the moment of stabilizing the DC voltage at nominal value, the AC-AC power converter can operates in the proper limits. The functions of the control structure are: the load control task, speed and torque controls. System includes transducers for current measuring, voltage sensors and encoder. As reserve power sources the hybrid battery-photovoltaic panels are used. The control voltage is modulated by implementing four types of pulse width modulations: sinusoidal, with reduced commutation, third order harmonic insertion, and the space vector modulation. Therefore, the prototype could operates with an increased efficiency, in spite of the existing ones. The experimental results confirm the well design of the chosen solution. The control solution assures bidirectional power flow control, precharge control, and load control and it is implemented on a digital signal processor. The elevator capacity is between 300-450 kg, and it is driven by using a 1.5 kW three-phase asynchronous machine.

  14. Space-based Operations Grid Prototype

    Science.gov (United States)

    Bradford, Robert N.; Welch, Clara L.

    2003-01-01

    The Space based Operations Grid is intended to integrate the "high end" network services and compute resources that a remote payload investigator needs. This includes integrating and enhancing existing services such as access to telemetry, payload commanding, payload planning and internet voice distribution as well as the addition of services such as video conferencing, collaborative design, modeling or visualization, text messaging, application sharing, and access to existing compute or data grids. Grid technology addresses some of the greatest challenges and opportunities presented by the current trends in technology, i.e. how to take advantage of ever increasing bandwidth, how to manage virtual organizations and how to deal with the increasing threats to information technology security. We will discuss the pros and cons of using grid technology in space-based operations and share current plans for the prototype. It is hoped that early on the prototype can incorporate many of the existing as well as future services that are discussed in the first paragraph above to cooperating International Space Station Principle Investigators both nationally and internationally.

  15. Prototyping Advanced Control Systems on FPGA

    Directory of Open Access Journals (Sweden)

    Simard Stéphane

    2009-01-01

    Full Text Available In advanced digital control and mechatronics, FPGA-based systems on a chip (SoCs promise to supplant older technologies, such as microcontrollers and DSPs. However, the tackling of FPGA technology by control specialists is complicated by the need for skilled hardware/software partitioning and design in order to match the performance requirements of more and more complex algorithms while minimizing cost. Currently, without adequate software support to provide a straightforward design flow, the amount of time and efforts required is prohibitive. In this paper, we discuss our choice, adaptation, and use of a rapid prototyping platform and design flow suitable for the design of on-chip motion controllers and other SoCs with a need for analog interfacing. The platform consists of a customized FPGA design for the Amirix AP1000 PCI FPGA board coupled with a multichannel analog I/O daughter card. The design flow uses Xilinx System Generator in Matlab/Simulink for system design and test, and Xilinx Platform Studio for SoC integration. This approach has been applied to the analysis, design, and hardware implementation of a vector controller for 3-phase AC induction motors. It also has contributed to the development of CMC's MEMS prototyping platform, now used by several Canadian laboratories.

  16. Space-based Science Operations Grid Prototype

    Science.gov (United States)

    Bradford, Robert N.; Welch, Clara L.; Redman, Sandra

    2004-01-01

    Grid technology is the up and coming technology that is enabling widely disparate services to be offered to users that is very economical, easy to use and not available on a wide basis. Under the Grid concept disparate organizations generally defined as "virtual organizations" can share services i.e. sharing discipline specific computer applications, required to accomplish the specific scientific and engineering organizational goals and objectives. Grids are emerging as the new technology of the future. Grid technology has been enabled by the evolution of increasingly high speed networking. Without the evolution of high speed networking Grid technology would not have emerged. NASA/Marshall Space Flight Center's (MSFC) Flight Projects Directorate, Ground Systems Department is developing a Space-based Science Operations Grid prototype to provide to scientists and engineers the tools necessary to operate space-based science payloads/experiments and for scientists to conduct public and educational outreach. In addition Grid technology can provide new services not currently available to users. These services include mission voice and video, application sharing, telemetry management and display, payload and experiment commanding, data mining, high order data processing, discipline specific application sharing and data storage, all from a single grid portal. The Prototype will provide most of these services in a first step demonstration of integrated Grid and space-based science operations technologies. It will initially be based on the International Space Station science operational services located at the Payload Operations Integration Center at MSFC, but can be applied to many NASA projects including free flying satellites and future projects. The Prototype will use the Internet2 Abilene Research and Education Network that is currently a 10 Gb backbone network to reach the University of Alabama at Huntsville and several other, as yet unidentified, Space Station based

  17. A Computuerized Operator Support System Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Ken Thomas; Ronald Boring; Roger Lew; Tom Ulrich; Richard Villim

    2013-08-01

    A report was published by the Idaho National Laboratory in September of 2012, entitled Design to Achieve Fault Tolerance and Resilience, which described the benefits of automating operator actions for transients. The report identified situations in which providing additional automation in lieu of operator actions would be advantageous. It recognized that managing certain plant upsets is sometimes limited by the operator’s ability to quickly diagnose the fault and to take the needed actions in the time available. Undoubtedly, technology is underutilized in the nuclear power industry for operator assistance during plant faults and operating transients. In contrast, other industry sectors have amply demonstrated that various forms of operator advisory systems can enhance operator performance while maintaining the role and responsibility of the operator as the independent and ultimate decision-maker. A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. The COSS does not supplant the role of the operator, but rather provides rapid assessments, computations, and recommendations to reduce workload and augment operator judgment and decision-making during fast-moving, complex events. This project proposes a general model for a control room COSS that addresses a sequence of general tasks required to manage any plant upset: detection, validation, diagnosis, recommendation, monitoring, and recovery. The model serves as a framework for assembling a set of technologies that can be interrelated to assist with each of these tasks. A prototype COSS has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based

  18. A Computuerized Operator Support System Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Ken Thomas; Ronald Boring; Roger Lew; Tom Ulrich; Richard Villim

    2013-11-01

    A report was published by the Idaho National Laboratory in September of 2012, entitled Design to Achieve Fault Tolerance and Resilience, which described the benefits of automating operator actions for transients. The report identified situations in which providing additional automation in lieu of operator actions would be advantageous. It recognized that managing certain plant upsets is sometimes limited by the operator’s ability to quickly diagnose the fault and to take the needed actions in the time available. Undoubtedly, technology is underutilized in the nuclear power industry for operator assistance during plant faults and operating transients. In contrast, other industry sectors have amply demonstrated that various forms of operator advisory systems can enhance operator performance while maintaining the role and responsibility of the operator as the independent and ultimate decision-maker. A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. The COSS does not supplant the role of the operator, but rather provides rapid assessments, computations, and recommendations to reduce workload and augment operator judgment and decision-making during fast-moving, complex events. This project proposes a general model for a control room COSS that addresses a sequence of general tasks required to manage any plant upset: detection, validation, diagnosis, recommendation, monitoring, and recovery. The model serves as a framework for assembling a set of technologies that can be interrelated to assist with each of these tasks. A prototype COSS has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based

  19. Deep drawing experiences of niobium disk for PEFP SRF cavity prototype

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Han Sung; An, Sun; Zhang, Liping; Tang, Yazhe; Li, Ying Min; Kwon, Hyeok Jung; Cho, Yong Sub [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2009-05-15

    A superconducting radio frequency (SRF) cavity with a geometrical beta of 0.42 has been designed to accelerate a proton beam after 100 MeV for an extension of Proton Engineering Frontier Project (PEFP). The designed cavity shape is an elliptical and the resonant frequency is 700 MHz. In order to confirm the RF and mechanical properties of the cavity, two prototypes of copper cavities have been fabricated and tested. Based on the experiences gained with the copper prototypes, two niobium prototypes have been designed. One is two-cell cavity and the other is five cell cavity. The two-cell cavity is for finalizing the niobium cavity production procedure and testing the cavity RF properties at a low temperature and moderate power level. The five-cell cavity is for checking the production quality and testing vertical test system in the future. Both of them are under fabrication. Through the fabrication of the niobium prototype, several issues such as deep drawing, electron beam welding and surface treatment will be addressed. The drawing of the PEPF SRF low beta cavity is shown in Fig. 1. Major parameters for the cavity are like following. - Frequency: 700 MHz - Operating mode: TM010 pi mode - Cavity type: Elliptical - Geometrical beta: 0.42 - Number of cells: 5 per cavity - Accelerating gradient: 8 MV/m - Epeak/Eacc: 3.71 - Bpeak/Eacc: 7.47 mT/(MV/m) - R/Q: 102.3 ohm - Epeak: 29.68 MV/m - Field flatness: 1.56 % - Cell to cell coupling: 1.41 % - Geometrical factor: 121.68 ohm - Cavity wall thickness: 4.3 mm - Lorentz force detuning: 0.4 Hz/(MV/m)2 - Stiffening structure: Double ring - Effective length: 0.45 m - External Q of FPC: 8.0E5 {+-}20 % - HOM load: less than 2 W - HOM Qext requirement: less than 3.0E5 At present, all the niobium disk and plates for cavity and NbTi flanges for beam pipe flange are prepared.

  20. Laser-Sintern. Die Schluesseltechnologie des e-Manufacturing TM

    OpenAIRE

    Lenz, Jörg

    2004-01-01

    e-Manufacturing™, das ist die schnelle, flexible und kostengünstige Fertigung von Produkten, Formen/Werkzeugen oder Modellen direkt aus elektronischen Daten. e-Manufacturing™ schließt Rapid Prototyping, Rapid Tooling oder Rapid Manufacturing ein, geht aber zugleich weit über den Gedanken der schnellen Verfügbarkeit hinaus. Zwar wird auch in Zukunft die schnelle Produktentwicklung eine immer wichtigere Rolle spielen, bei der e-Manufacturing™ für ein verkürztes Time ...

  1. 76 FR 15047 - Pricing for 2010 United States Mint America the Beautiful Quarters Silver Proof SetTM

    Science.gov (United States)

    2011-03-18

    ... United States Mint Pricing for 2010 United States Mint America the Beautiful Quarters Silver Proof Set\\TM\\, etc. ACTION: Pricing for 2010 United States Mint America the Beautiful Quarters Silver Proof Set TM ; 2010 United States Mint Silver Proof Set TM ; 2011 United States Mint America the Beautiful...

  2. Possible undercompensation effect in the Kondo insulator (Yb,Tm)B12

    Science.gov (United States)

    Alekseev, P. A.; Nemkovski, K. S.; Mignot, J.-M.; Clementyev, E. S.; Ivanov, A. S.; Rols, S.; Bewley, R. I.; Filipov, V. B.; Shitsevalova, N. Yu.

    2014-03-01

    The effects of Tm substitution on the dynamical magnetic response of Yb1-xTmxB12 (x=0, 0.08, 0.15, and 0.75) and Lu0.92Tm0.08B12 compounds have been studied using time-of-flight inelastic neutron scattering. Major changes were observed in the spectral structure and temperature evolution of the Yb contribution to the inelastic response for a rather low content of magnetic Tm ions. A sizable influence of the RB12 host (YbB12, as compared to LuB12 or pure TmB12) on the crystal-field splitting of the Tm3+ ion is also reported. The results point to a specific effect of impurities carrying a magnetic moment (Tm, as compared to Lu or Zr) in a Kondo insulator, which is thought to reflect the "undercompensation" of Yb magnetic moments, originally Kondo screened in pure YbB12. A parallel is made with the strong effect of Tm substitution on the temperature dependence of the Seebeck coefficient in Yb1-xTmxB12, which was reported previously.

  3. Using Landsat TM data to model corn and soybean yields

    Science.gov (United States)

    Candanedo Guevara, Martin Edmundo

    2001-07-01

    Early research in agriculture used remotely sensed data mostly for the identification of spectral signatures, where crop type/area classification would depend on data acquired from hand-held or truck-mounted instruments. Through time different approaches were taken for crop type/area classification, such as a systematic sampling of inventory ground data that were used later for training and testing using image processing techniques. Later, technology such as the global positioning system (GPS) and geographic information systems (GIS) were used for application to precision agriculture. These new tools provided a better meaning to understand and analyze the complex variability of the crop-soil-atmosphere system to estimate crop yields. The present research used data collected in the Management System Evaluation Area (MSEA) in 1998 and two Landsat thematic Mapper images (July and August) to analyze the crop variability. Ground truth parameters, such as chlorophyll, leaf area index (LAI), and electricity conductivity, were collected throughout the growing season. In addition, vegetation indexes (VI) such as the Normalized difference vegetation index (NDVI), simple vegetation index (SVI), soil adjusted ratio vegetation index (SARVI), were computed for the two images. Both ground truth data and VI's were statistically analyzed with yield measurements taken with an on-the-go yield monitor to estimate a best fit yield model for use with soybeans and corn. The correlation analysis within a Landsat pixel reported SVI52 (r = 0.62), SVI53 (r = 0.56), and SVI54 (r = 0.53) as the most significant relationships. The results from the ground truth data vs. on-the-go yields reported total clay (%) (r = 0.90), leaf area (r = 0.76), and tissue plant analysis (r = 0.73) A stepwise regression analysis was performed using the Landsat TM images and the VI's selected. A series of linear models were evaluated taking into account the Landsat TM and yield while varying the scale (1 pixel to

  4. Phenotypic and Physiological Characterization of the Epibiotic Interaction Between TM7x and Its Basibiont Actinomyces.

    Science.gov (United States)

    Bor, Batbileg; Poweleit, Nicole; Bois, Justin S; Cen, Lujia; Bedree, Joseph K; Zhou, Z Hong; Gunsalus, Robert P; Lux, Renate; McLean, Jeffrey S; He, Xuesong; Shi, Wenyuan

    2016-01-01

    Despite many examples of obligate epibiotic symbiosis (one organism living on the surface of another) in nature, such an interaction has rarely been observed between two bacteria. Here, we further characterize a newly reported interaction between a human oral obligate parasitic bacterium TM7x (cultivated member of Candidatus Saccharimonas formerly Candidate Phylum TM7), and its basibiont Actinomyces odontolyticus species (XH001), providing a model system to study epiparasitic symbiosis in the domain Bacteria. Detailed microscopic studies indicate that both partners display extensive morphological changes during symbiotic growth. XH001 cells manifested as short rods in monoculture, but displayed elongated and hyphal morphology when physically associated with TM7x. Interestingly, these dramatic morphological changes in XH001 were also induced in oxygen-depleted conditions, even in the absence of TM7x. Targeted quantitative real-time PCR (qRT-PCR) analyses revealed that both the physical association with TM7x as well as oxygen depletion triggered up-regulation of key stress response genes in XH001, and in combination, these conditions act in an additive manner. TM7x and XH001 co-exist with relatively uniform cell morphologies under nutrient-replete conditions. However, upon nutrient depletion, TM7x-associated XH001 displayed a variety of cell morphologies, including swollen cell body, clubbed-ends, and even cell lysis, and a large portion of TM7x cells transformed from ultrasmall cocci into elongated cells. Our study demonstrates a highly dynamic interaction between epibiont TM7x and its basibiont XH001 in response to physical association or environmental cues such as oxygen level and nutritional status, as reflected by their morphological and physiological changes during symbiotic growth.

  5. Integrating TM and Ancillary Geographical Data with Classification Trees for Land Cover Classification of Marsh Area

    Institute of Scientific and Technical Information of China (English)

    NA Xiaodong; ZHANG Shuqing; ZHANG Huaiqing; LI Xiaofeng; YU Huan; LIU Chunyue

    2009-01-01

    The main objective of this research is to determine the capacity of land cover classification combining spectral and textural features of Landsat TM imagery with ancillary geographical data in wetlands of the Sanjiang Plain, Heilongjiang Province, China. Semi-variograms and Z-test value were calculated to assess the separability of grey-level co-occurrence texture measures to maximize the difference between land cover types. The degree of spatial autocorrelation showed that window sizes of 3×3 pixels and 11×11 pixels were most appropriate for Landsat TM image texture calculations. The texture analysis showed that co-occurrence entropy, dissimilarity, and variance texture measures, derived from the Landsat TM spectrum bands and vegetation indices provided the most significant statistical differentiation between land cover types. Subsequently, a Classification and Regression Tree (CART) algorithm was applied to three different combinations of predictors: 1) TM imagery alone (TM-only); 2) TM imagery plus image texture (TM+TXT model); and 3) all predictors including TM imagery, image texture and additional ancillary GIS information (TM+TXT+GIS model). Compared with traditional Maximum Likelihood Classification (MLC) supervised classification, three classification trees predictive models reduced the overall error rate significantly. Image texture measures and ancillary geographical variables depressed the speckle noise effectively and reduced classification error rate of marsh obviously. For classification trees model making use of all available predictors, omission error rate was 12.90% and commission error rate was 10.99% for marsh. The developed method is portable, relatively easy to implement and should be applicable in other settings and over larger extents.

  6. A Novel Role for Tm7sf2 Gene in Regulating TNFα Expression

    Science.gov (United States)

    Bellezza, Ilaria; Roberti, Rita; Gatticchi, Leonardo; Del Sordo, Rachele; Rambotti, Maria Grazia; Marchetti, Maria Cristina; Sidoni, Angelo; Minelli, Alba

    2013-01-01

    We have explored the role of Tm7sf2 gene, which codifies for 3β-hydroxysterol Δ14-reductase, an endoplasmic reticulum resident protein, in the sensitivity to endoplasmic reticulum stress and in the resulting inflammatory response. We used mouse embryonic fibroblasts, derived from Tm7sf2+/+ and Tm7sf2−/− mice, to determine the in vitro effects of thapsigargin on NF-κB activation. Our results show that the Tm7sf2 gene controls the launch of the unfolded protein response and presides an anti-inflammatory loop thus its absence correlates with NF-κB activation and TNFα up-regulation. Our data also show that Tm7sf2 gene regulates liver X receptor activation and its absence inhibits LXR signalling. By expressing the hTm7sf2 gene in KO MEFs and observing a reduced NF-κB activation, we have confirmed that Tm7sf2 gene is linked to NF-κB activation. Finally we used genetically modified mice in an in vivo model of ER stress and of inflammation. Our results show a significant increase in renal TNFα expression after tunicamycin exposure and in the oedematogenic response in Tm7sf2−/− mice. In conclusion, we have shown that the Tm7sf2 gene, to date involved only in cholesterol biosynthesis, also controls an anti-inflammatory loop thereby confirming the existence of cross talk between metabolic pathways and inflammatory response. PMID:23935851

  7. A MEMS turbine prototype for respiration harvesting

    Science.gov (United States)

    Goreke, U.; Habibiabad, S.; Azgin, K.; Beyaz, M. I.

    2015-12-01

    The design, manufacturing, and performance characterization of a MEMS-scale turbine prototype is reported. The turbine is designed for integration into a respiration harvester that can convert normal human breathing into electrical power through electromagnetic induction. The device measures 10 mm in radius, and employs 12 blades located around the turbine periphery along with ball bearings around the center. Finite element simulations showed that an average torque of 3.07 μNm is induced at 12 lpm airflow rate, which lies in normal breathing levels. The turbine and a test package were manufactured using CNC milling on PMMA. Tests were performed at respiration flow rates between 5-25 lpm. The highest rotational speed was measured to be 9.84 krpm at 25 lpm, resulting in 8.96 mbar pressure drop across the device and 370 mW actuation power.

  8. Stochastic bifurcations in a prototypical thermoacoustic system.

    Science.gov (United States)

    Gopalakrishnan, E A; Tony, J; Sreelekha, E; Sujith, R I

    2016-08-01

    We study the influence of noise in a prototypical thermoacoustic system, which represents a nonlinear self-excited bistable oscillator. We analyze the time series of unsteady pressure obtained from a horizontal Rijke tube and a mathematical model to identify the effect of noise. We report the occurrence of stochastic bifurcations in a thermoacoustic system by tracking the changes in the stationary amplitude distribution. We observe a complete suppression of a bistable zone in the presence of high intensity noise. We find that the complete suppression of the bistable zone corresponds to the nonexistence of phenomenological (P) bifurcations. This is a study in thermoacoustics to identify the parameter regimes pertinent to P bifurcation using the stationary amplitude distribution obtained by solving the Fokker-Planck equation.

  9. ADPKD: Prototype of Cardiorenal Syndrome Type 4

    Directory of Open Access Journals (Sweden)

    Grazia Maria Virzì

    2011-01-01

    Full Text Available The cardiorenal syndrome type 4 (Chronic Renocardiac Syndrome is characterized by a condition of primary chronic kidney disease (CKD that leads to an impairment of the cardiac function, ventricular hypertrophy, diastolic dysfunction, and/or increased risk of adverse cardiovascular events. Clinically, it is very difficult to distinguish between CRS type 2 (Chronic Cardiorenal Syndrome and CRS type 4 (Chronic Renocardiac Syndrome because often it is not clear whether the primary cause of the syndrome depends on the heart or the kidney. Autosomal dominant polycystic kidney disease (ADPKD, a genetic disease that causes CKD, could be viewed as an ideal prototype of CRS type 4 because it is certain that the primary cause of cardiorenal syndrome is the kidney disease. In this paper, we will briefly review the epidemiology of ADPKD, conventional and novel biomarkers which may be useful in following the disease process, and prevention and treatment strategies.

  10. MATLAB tensor classes for fast algorithm prototyping.

    Energy Technology Data Exchange (ETDEWEB)

    Bader, Brett William; Kolda, Tamara Gibson (Sandia National Laboratories, Livermore, CA)

    2004-10-01

    Tensors (also known as mutidimensional arrays or N-way arrays) are used in a variety of applications ranging from chemometrics to psychometrics. We describe four MATLAB classes for tensor manipulations that can be used for fast algorithm prototyping. The tensor class extends the functionality of MATLAB's multidimensional arrays by supporting additional operations such as tensor multiplication. The tensor as matrix class supports the 'matricization' of a tensor, i.e., the conversion of a tensor to a matrix (and vice versa), a commonly used operation in many algorithms. Two additional classes represent tensors stored in decomposed formats: cp tensor and tucker tensor. We descibe all of these classes and then demonstrate their use by showing how to implement several tensor algorithms that have appeared in the literature.

  11. Characterization of the ATLAS Micromegas quadruplet prototype

    Science.gov (United States)

    Sidiropoulou, O.; Bianco, M.; Danielsson, H.; Degrange, J.; Farina, E. M.; Gomez, F. P.; Iengo, P.; Kuger, F.; Lin, T. H.; Schott, M.; Sekhniaidze, G.; Valderanis, C.; Vergain, M.; Wotschack, J.

    2016-07-01

    A Micromegas [1] detector with four active layers, serving as prototype for the upgrade of the ATLAS muon spectrometer [2], was designed and constructed in 2014 at CERN and represents the first example of a Micromegas quadruplet ever built. The detector has been realized using the resistive-strip technology and decoupling the amplification mesh from the readout structure. The four readout layers host overall 4096 strips with a pitch of 415 μm; two layers have strips running parallel (η in the ATLAS reference system, for measuring the muon bending coordinate) and two layers have inclined strips by ±1.5° angle with respect to the η coordinate in order to provide measurement of the second coordinate. A detector characterization carried out with cosmic muons and under X-ray irradiation is presented with the obtained results.

  12. Flight research with the MIT Daedalus prototype

    Science.gov (United States)

    Bussolari, Steven R.; Youngren, Harold H.; Langford, John S.

    1987-01-01

    The MIT Light Eagle human-powered aircraft underwent long-duration testing over Rogers Dry Lake in California during January, 1987. Designed as a prototype for the MIT Daedalus Project, the Light Eagle's forty-eight flights provided pilot training, established new distance records for human-powered flight, and provided quantitative data through a series of instrumented flight experiments. The experiments focused on: (1) evaluating physiological loads on the pilot, (2) determining airframe power requirements, and (3) developing an electronic flight control system. This paper discusses the flight test program, its results and their implications for the follow-on Daedalus aircraft, and the potential uses of the Light Eagle as a low Reynolds number testbed.

  13. The SSC full cell prototype string test

    International Nuclear Information System (INIS)

    At the conclusion of the SSC half cell magnet string testing program. In February, 1993, the preliminary data analysis revealed that several substantive technical questions remained unresolved. These questions were: (1) could the high voltages to ground (>2 kV) measured during fault (quench) conditions be substantially reduced, (2) could the number of magnetic elements that became resistive (quenched) be controlled and (3) did the cryostats of the magnetic elements provide adequate insulation and isolation to meet designed refrigeration loads. To address these and other existing question a prototypical full cell of collider magnets (ten dipoles and two quadrupoles) was assembled and tested. At the conclusion of this testing there were definitive answers to most of the questions with numerical substantiation, the notable exception being the beat leak question. These answers and other results and issues are presented in this paper

  14. The SSC full cell prototype string test

    International Nuclear Information System (INIS)

    At the conclusion of the SSC half cell magnet string testing program in February, 1993, the preliminary data analysis revealed that several substantive technical questions remained unresolved. These questions were: (1) could the high voltages to ground (>2 kV) measured during fault (quench) conditions be substantially reduced, (2) could the number of magnetic elements that became resistive (quenched) be controlled and 3) did the cryostats of the magnetic elements provide adequate insulation and isolation to meet designed refrigeration loads. To address these and other existing questions, a prototypical fall cell of collider magnets (ten dipoles and two quadrupoles) was assembled and tested. At the conclusion of this testing there were definitive answers to most of the questions with numerical substantiation, the notable exception being the beat leak question. These answers and other results and issues are presented in this paper

  15. Results of the prototype camera for FACT

    Energy Technology Data Exchange (ETDEWEB)

    Anderhub, H. [ETH Zurich, Institute for Particle Physics, CH-8093 Zurich (Switzerland); Backes, M. [Technische Universitaet Dortmund, D-44221 Dortmund (Germany); Biland, A.; Boller, A.; Braun, I. [ETH Zurich, Institute for Particle Physics, CH-8093 Zurich (Switzerland); Bretz, T. [Ecole Polytechnique Federale de Lausanne, CH-1015 Lausanne (Switzerland); Commichau, S.; Commichau, V. [ETH Zurich, Institute for Particle Physics, CH-8093 Zurich (Switzerland); Dorner, D. [ETH Zurich, Institute for Particle Physics, CH-8093 Zurich (Switzerland); INTEGRAL Science Data Center, CH-1290 Versoix (Switzerland); Gendotti, A.; Grimm, O.; Gunten, H. von; Hildebrand, D.; Horisberger, U. [ETH Zurich, Institute for Particle Physics, CH-8093 Zurich (Switzerland); Koehne, J.-H. [Technische Universitaet Dortmund, D-44221 Dortmund (Germany); Kraehenbuehl, T., E-mail: thomas.kraehenbuehl@phys.ethz.c [ETH Zurich, Institute for Particle Physics, CH-8093 Zurich (Switzerland); Kranich, D.; Lorenz, E.; Lustermann, W. [ETH Zurich, Institute for Particle Physics, CH-8093 Zurich (Switzerland); Mannheim, K. [Universitaet Wuerzburg, D-97074 Wuerzburg (Germany)

    2011-05-21

    The maximization of the photon detection efficiency (PDE) is a key issue in the development of cameras for Imaging Atmospheric Cherenkov Telescopes. Geiger-mode Avalanche Photodiodes (G-APD) are a promising candidate to replace the commonly used photomultiplier tubes by offering a larger PDE and in addition a facilitated handling. The FACT (First G-APD Cherenkov Telescope) project evaluates the feasibility of this change by building a camera based on 1440 G-APDs for an existing small telescope. As a first step towards a full camera, a prototype module using 144 G-APDs was successfully built and tested. The strong temperature dependence of G-APDs is compensated using a feedback system, which allows to keep the gain of the G-APDs constant to 0.5%.

  16. Manufacture for prototype Mo-99 irradiation target

    International Nuclear Information System (INIS)

    The prototype of target to produce Mo-99 by fission has been manufactured. Extension equipment using oil pressure is specially designed and fabricated in order to prepare the Mo-99 target of high quality to be irradiated in a research reactor. The target of an annular type of inner and outer Al tubes and uranium foil in between is extended using a dedicated tool with a draw plug. The inner tube is plastically deformed while the outer tube is elastically deformed. This makes the Al tubes and foil contacted closely. Top and bottom ends of the target are welded by TIG in order to provide a hermetic sealing which will prevent the release of fission gases during the irradiation

  17. Rapid prototyping of ossicular replacement prostheses

    Science.gov (United States)

    Ovsianikov, A.; Chichkov, B.; Adunka, O.; Pillsbury, H.; Doraiswamy, A.; Narayan, R. J.

    2007-05-01

    Materials used in ossicular replacement prostheses must demonstrate appropriate biological compatibility, acoustic transmission, stability, and stiffness properties. Prostheses prepared using Teflon ®, titanium, Ceravital and other conventional materials have demonstrated several problems, including migration, perforation of the tympanic membrane, difficulty in shaping the prostheses, and reactivity with the surrounding tissues. We have used two-photon polymerization for rapid prototyping of Ormocer ® middle-ear bone replacement prostheses. Ormocer ® surfaces fabricated using two-photon polymerization exhibited acceptable cell viability and cell growth profiles. The Ormocer ® prosthesis was able to be inserted and removed from the site of use in the frozen human head without fracture. Our results demonstrate that two-photon polymerization is able to create ossicular replacement prostheses and other medical devices with a larger range of sizes, shapes and materials than other microfabrication techniques.

  18. Safeguards in Prototype Fast Breeder Reactor Monju

    International Nuclear Information System (INIS)

    The assemblies loaded in the core and stored in the ex-vessel storage tank (EVST) are in liquid sodium in the Japanese prototype fast breeder reactor (FBR) Monju. Since it is difficult to apply a direct verification procedure for the fuel assemblies in these areas, a dual containment and surveillance system consisting of two monitoring devices such as surveillance camera and radiation monitor that are functionally independent has been applied. In addition, the Monju Remote Monitoring System was developed to strengthen the continuous surveillance and to reduce the load of the inspection activities. Furthermore, the ex-vessel transfer machine radiation monitor (EVRM) and the exit gate monitor (EXGM) were upgraded to strengthen the monitoring of spent blanket fuel assemblies and to improve the reliability of distinguishing between fuel assemblies and non-fuel items. As the result, the integrated safeguards was introduced in November 2009, and the effective safeguards activities have been implemented in Monju. (author)

  19. Design Study: ELENA Bending Magnet Prototype

    CERN Document Server

    Schoerling, D

    2013-01-01

    The ELENA bending magnet prototype shall prove that the proposed design meets the requirements set by the ELENA beam dynamics. The following points will be discussed in detail: (i) production process of a magnetic yoke diluted with stainless steel plates, (ii) the stability and repeatability of the field homogeneity of such a yoke over the full working range, (iii) choice of soft magnetic steel, (iv) hysteresis effects, (v) mechanical deformations, (vi) thermal insulation to intercept heat load from baking for activation of NEG coating in the vacuum chamber, (vii) end shim design. In order to verify these points the following measurements will be performed: (i) Hall probe scanning, (ii) integrated field homogeneity measurement (DC), (iii) integrated field homogeneity measurement (AC).

  20. Stochastic bifurcations in a prototypical thermoacoustic system

    Science.gov (United States)

    Gopalakrishnan, E. A.; Tony, J.; Sreelekha, E.; Sujith, R. I.

    2016-08-01

    We study the influence of noise in a prototypical thermoacoustic system, which represents a nonlinear self-excited bistable oscillator. We analyze the time series of unsteady pressure obtained from a horizontal Rijke tube and a mathematical model to identify the effect of noise. We report the occurrence of stochastic bifurcations in a thermoacoustic system by tracking the changes in the stationary amplitude distribution. We observe a complete suppression of a bistable zone in the presence of high intensity noise. We find that the complete suppression of the bistable zone corresponds to the nonexistence of phenomenological (P) bifurcations. This is a study in thermoacoustics to identify the parameter regimes pertinent to P bifurcation using the stationary amplitude distribution obtained by solving the Fokker-Planck equation.

  1. SuperB Muon Detector Prototype

    International Nuclear Information System (INIS)

    The test objective is to optimize the muon identification in an experiment at a Super B Factory. To accomplish this, experimenters will study the muon identification capability of a detector with different iron configurations at different beam energies. The detector is a full scale prototype, composed of a stack of iron tiles. The segmentation of the iron allows the study of different configurations. Between the tiles, one or two extruded scintillator slabs can be inserted to test two different readout options; a Binary Readout and a Time Readout. In the Binary Readout option the two coordinates are given by the two orthogonal scintillator bars, and the spatial resolution is driven by the bar width. In the Time Readout option one coordinate is determined by the scintillator position and the other by the arrival time of the signal read with a TDC.

  2. PMT overshoot study for JUNO prototype detector

    CERN Document Server

    Luo, F J; Wang, Z M; Wang, P L; Qin, Z H; Xu, M H; Liao, D H; Zhang, H Q; Lei, X C; Qian, S; Liu, S L; Chen, Y B; Wang, Y F

    2016-01-01

    The quality of PMT signal is one of the key items for a large and high precision neutrino experiment, like Daya Bay, JUNO, while most of the experiments are affected by the PMT signal overshoot from its positive HV-single cable scheme. For JUNO prototype detector, we have a detailed study on the PMT overshoot and successfully reduced the ratio of overshoot amplitude to signal to ~1% from previous typical ~10%, with no affection to PMT other parameters. Furthermore, we calculated that the overshoot is a result of discharging of capacitors in the HV-signal splitter and the PMT voltage divider. The study result is extremely important for JUNO and other similar experiments.

  3. ANTARES: A Prototype Transient Broker System

    CERN Document Server

    Saha, Abhijit; Snodgrass, Richard; Kececioglu, John; Narayan, Gautham; Seaman, Robert; Jenness, Tim; Axelrod, Tim

    2014-01-01

    The Arizona-NOAO Temporal Analysis and Response to Events System (ANTARES) is a joint project of the National Optical Astronomy Observatory and the Department of Computer Science at the University of Arizona. The goal is to build the software infrastructure necessary to process and filter alerts produced by time-domain surveys, with the ultimate source of such alerts being the Large Synoptic Survey Telescope (LSST). The ANTARES broker will add value to alerts by annotating them with information from external sources such as previous surveys from across the electromagnetic spectrum. In addition, the temporal history of annotated alerts will provide further annotation for analysis. These alerts will go through a cascade of filters to select interesting candidates. For the prototype, `interesting' is defined as the rarest or most unusual alert, but future systems will accommodate multiple filtering goals. The system is designed to be flexible, allowing users to access the stream at multiple points throughout the...

  4. Point contact spectroscopy of SmB6, TmSe, ''gold'' SmS and TmSesub(1-x)Tesub(x): gaps

    International Nuclear Information System (INIS)

    The dynamic resistance dU/dI(U) and its derivative d2U/dI2(U) were measured of point contacts with intermediate valent SmB6, ''gold''SmS, TmSe and ferromagnetic TmSesub(0.82)Tesub(0.18) and their integer valent reference compounds LaB6, LaS, LaSe and Tmsub(0.87)Se at liquid helium temperatures. While dU/dI(U) of point contacts with the integer valent compounds does not show any anomalous structures, SmB6, ''gold''SmS and TmSe (in the antiferromagnetic phase) exhibit a strong resistance peak at zero bias with a characteristic width of 5 meV, 6.5 meV and 2.5 meV, respectively. This is taken as evidence of hybridization gaps. Point contacts with ferromagnetic TmSesub(0.82)Tesub(0.18) show below Tsub(c) a shape of dU/dI(U) which is similar to that of TmSe in its field induced ferromagnetic phase. (Auth.)

  5. Advanced ASON prototyping research activities in China

    Science.gov (United States)

    Hu, WeiSheng; Jin, Yaohui; Guo, Wei; Su, Yikai; He, Hao; Sun, Weiqiang

    2005-02-01

    This paper provides an overview of prototyping research activities of automatically switched optical networks and transport networks (ASONs/ASTNs) in China. In recent years, China has recognized the importance and benefits of the emerging ASON/ASTN techniques. During the period of 2001 and 2002, the national 863 Program of China started the preliminary ASON research projects with the main objectives to build preliminary ASON testbeds, develop control plane protocols and test their performance in the testbeds. During the period of 2003 and 2004, the 863 program started ASTN prototyping equipment projects for more practical applications. Totally 12 ASTN equipments are being developed by three groups led by Chinese venders: ZTE with Beijing University of Posts and Telecommunications (BUPT), Wuhan Research Institute of Posts and Telecommunication (WRI) with Shanghai Jiao Tong University (SJTU), and Huawei Inc. Meanwhile, as the ASTN is maturing, some of the China"s carries are participating in the OIF"s World Interoperability Demonstration, carrying out ASTN test, or deploying ASTN backbone networks. Finally, several ASTN backbone networks being tested or deployed now will be operated by the carries in 2005. The 863 Program will carry out an ASTN field trail in Yangtse River Delta, and finally deploy the 3TNET. 3TNET stands for Tbps transmission, Tbps switching, and Tbps routing, as well as a network integrating the above techniques. A task force under the "863" program is responsible for ASTN equipment specifications and interoperation agreements, technical coordination among all the participants, schedule of the whole project during the project undergoing, and organization of internetworking of all the equipments in the laboratories and field trials.

  6. Prototype Engineered Barrier System Field Tests (PEBSFT)

    International Nuclear Information System (INIS)

    This progress report presents the interpretation of data obtained (up to November 1, 1988) from the Prototype Engineered Barrier System Field Tests (PEBSFT) that are being performed for the Yucca Mountain Project (YMP) in G-Tunnel within the Nevada Test site. The PEBSFTs are being conducted to evaluate the applicability of measurement techniques, numerical models, and procedures developed for the field tests for future investigations that will be conducted in the Exploratory Shaft Facilities, at a potential high-level radioactive waste repository site in Yucca Mountain. The primary objective of the tests is to provide the basis for determining whether tests planned for Yucca Mountain have the potential to be successful. Thirteen chapters discuss the following: mapping the electromagnetic permittivity and attenuation rate of the rock mass; changes in moisture content detected by the neutron logging probe; characterization of the in-situ permeability of the fractured tuff around the heater borehole; electrical resistance heater installed in a 30-cm borehole; relative humidity measurements; the operation, design, construction, calibration, and installation of a microwave circuit that might provide partial pressure information at temperatures in excess of 200 degree C (392 degree F); pressure and temperature measurements in the G-Tunnel; the moisture collection system, which attempts to collect steam that migrates into the heater borehole; The borehole television and borescope surveys that were performed to map the location, orientation, and aperture of the fractures intersecting the boreholes; preliminary scoping calculations of the hydrothermal conditions expected for this prototype test; the Data Acquisition System; and the results of the PEBSFT, preliminary interpretations of these results, and plans for the remainder of the test. Chapters have been indexed separately for inclusion on the data base

  7. The Prototype of GAMMA-400 Apparatus

    Science.gov (United States)

    Arkhangelskiy, A. I.; Arkhangelskaja, I. V.; Kheymits, M. D.; Runtso, M. F.; Suchkov, S. I.; Topchiev, N. P.; Yurkin, Yu. T.

    Scientific project GAMMA-400 (Gamma-Astronomy Multifunction Modules Apparatus) relates to the new generation of space observatories for investigation of cosmic γ-emission in the energy band from ∼20 MeV up to several TeV, electron/positron fluxes from ∼1 GeV up to ∼10 TeV and cosmic-ray nuclei fluxes with energies up to ∼1015 eV by means of GAMMA-400 gamma-telescope represents the core of the scientific complex. The investigation of gamma ray bursts in the energy band of 10 keV-15 MeV are possible too by means of KONUS-FG apparatus included in the complex. For γ-rays in the energy region from 10 to 100 GeV expected energy resolution changes from ∼3% to ∼1% and angular resolution from ∼0.1% to ∼ 0.01% respectively, γ/protons rejection factor is ∼5·105. The GAMMA-400 satellite will be launched at the beginning of the next decade on the high apogee orbit with following initial parameters: apogee altitude ∼300000 km, perigee altitude ∼500 km, rotation period ∼7 days, inclination to the equator plane 51.4°. The active functioning interval will be 7-10 years. The scientific complex will have next main technical parameters: total weight ∼4100 kg, power consumption ∼2000 W, information quote 100 GByte/day. During the project development, the prototype of apparatus was created for working-off of the main apparatus construction units in laboratory conditions. The main distinctive features of the prototype are presented.

  8. Virtual prototype simulation on underwater hydraulic impingement shovel

    Institute of Scientific and Technical Information of China (English)

    LIU He-ping; LUO A-ni; MENG Qing-xin

    2007-01-01

    The virtual prototype technology is applied to the design of the hydraulic impingement shovel,which is to increase the reliability of the design. The work principle of hydraulic impingement shovel is expatiated, and its dynamic equations are established. The 3D model of virtual prototype is built by PRO/E. Then the couple between the mechanical body of prototype and the hydraulic system is completed by virtue of ADAMS. Finally, the simulation is made on the virtual prototype. The simulation results show that the design of underwater hydraulic impingement shovel is rational. The virtual prototype technology could lay sound foundation of successful manufacturing of physical prototype for the first time and offer highly effective and feasible means for the design and production of underwater equipments.

  9. A Rapid Prototyping Environment for Wireless Communication Embedded Systems

    Directory of Open Access Journals (Sweden)

    Bryan A. Jones

    2003-05-01

    Full Text Available This paper introduces a rapid prototyping methodology which overcomes important barriers in the design and implementation of digital signal processing (DSP algorithms and systems on embedded hardware platforms, such as cellular phones. This paper describes rapid prototyping in terms of a simulation/prototype bridge and in terms of appropriate language design. The simulation/prototype bridge combines the strengths of simulation and of prototyping, allowing the designer to develop and evaluate next-generation communications systems, partly in simulation on a host computer and partly as a prototype on embedded hardware. Appropriate language design allows designers to express a communications system as a block diagram, in which each block represents an algorithm specified by a set of equations. Software tools developed for this paper implement both concepts, and have been successfully used in the development of a next-generation code division multiple access (CDMA cellular wireless communications system.

  10. Amorphous TM1−xBx alloy particles prepared by chemical reduction (invited)

    DEFF Research Database (Denmark)

    Linderoth, Søren; Mørup, Steen

    1991-01-01

    Amorphous transition-metal boron (TM-B) alloy particles can be prepared by chemical reduction of TM ions by borohydride in aqueous solutions. ln the last few years systematic studies of the parameters which control the composition, and, in turn, many of the properties of the alloy particles, have...... been performed and are reviewed in the present paper. The most important preparation parameters which influence the composition are the concentration of the borohydride solution and the pH of the TM salt solution. By controlling these parameters it is possible to prepare amorphous alloy samples...

  11. Intense red upconversion luminescence from Tm3+/Yb3+ codoped transparent glass ceramic.

    Science.gov (United States)

    Xu, Wei; Chen, Jianmin; Wang, Peng; Zhang, Zhiguo; Cao, Wenwu

    2012-01-15

    Tm3+/Yb3+ codoped transparent glass ceramic containing β-PbF2 nanocrystals was successfully prepared. After thermal treatment, emissions from the state of Tm3+ excited by 980 nm laser were greatly quenched by cross relaxation and the 700 nm luminescence from Tm3+:3F2,3→3H6 transition was strongly enhanced. A nearly monochromatic red luminescence band was observed. Based on the luminescence decay curves and Judd-Ofelt analysis, the strengthened cross relaxation played an important role in such phenomenon. PMID:22854468

  12. TmDOTA -: A Sensitive Probe for MR Thermometry in Vivo

    Science.gov (United States)

    Zuo, Chun S.; Mahmood, Ashfaq; Sherry, A. Dean

    2001-07-01

    The lanthanide complex, thulium 1,4,7,10-tetraazacyclodo- decane-1,4,7,10-tetraacetic acid (TmDOTA-), has been investigated as an agent for MR thermometry in vivo. The chemical shifts of the TmDOTA- protons were highly sensitive to temperature at a clinically relevant field strength, yet insensitive to pH and the presence of Ca2+. Given the excellent stability of lanthanide-DOTA complexes and high thermal sensitivity, TmDOTA- is expected to be a good candidate for MR thermometry in vivo.

  13. Plant Generation of TM-1 via Tissue Culture

    Institute of Scientific and Technical Information of China (English)

    LIU Chuan-liang; LI Fu-guang; XU Leng-chun

    2008-01-01

    @@ Plant generation of TM-1 via tissue culture was established.The hypocotyledon sections as explants which were cultured in a series of improved MS media containing 0.05~0.10 mg · L-1 IAA, 0.1~0.15 mg · L-1 Kt,0.07~0.14 mg · L-1 2,4-D could produce a large number of calli which were easier to regeneration in this system.The calli,which were subcuhured in another MS media containing 0.03~0.05 mg · L-1 Kt for 3-4 times produced embryoid callus in a rate of 35%.Fifty-six somatic embryoid calli were subcultured in an improved MS medium containing 0.1 mg·L-1 BA and 0.1~0.15 mg · L-1 IAA for plant regenerating,and 47 cotton plantlets were regenerated from them.

  14. Mallard Use of Hen HousesTM in Eastern Ontario

    Directory of Open Access Journals (Sweden)

    Jim R. Fisher

    2006-06-01

    Full Text Available Nesting structures for ground-nesting waterfowl may be an effective technique for increasing nesting success in regions in which nest success is below the 15% threshold needed to maintain a stable population. We studied the occupancy rate of artificial nesting structures called hen housesTM by Mallards (Anas platyrhynchos nesting in two different wetland habitats, beaver ponds and sewage lagoons, in eastern Ontario during 1999–2001. We hypothesized that, because natural cover was sparse on sewage lagoons, Mallards would occupy hen houses at a higher rate on sewage lagoons than on beaver ponds. However, of the 248 hen houses distributed between beaver ponds and sewage lagoons, none was occupied by waterfowl. Common Grackles (Quiscalus quiscula were the only avian species that nested in hen houses. However, Mallards successfully nested directly under several structures (n = 6 when water levels were low enough to expose the ground beneath them. Mayfield daily nest survival estimates for Mallards nesting in natural cover were similar on sewage lagoons and beaver ponds for all years (mean = 0.99 and were higher than most published estimates. Factors such as nesting cover, predation pressures, and structure design and material may influence the use of artificial hen houses and should be considered when planning a hen house program outside of the Prairie Pothole Region.

  15. A prototype surgical manipulator for robotic intraocular micro surgery.

    Science.gov (United States)

    Mulgaonkar, Amit P; Hubschman, Jean-Pierre; Bourges, Jean-Louis; Jordan, Brett L; Cham, Christopher; Wilson, Jason T; Tsao, Tsu-Chin; Culjat, Martin O

    2009-01-01

    A prototype manipulator system was developed for ophthalmologic microsurgery. The system, consisting of two parallel X-Y stages, can mechanically maintain a fixed-point of rotation at the surface of the eye, potentially reducing trauma during surgical procedures. The initial prototype was designed to function in concert with the da Vinci Surgical System for gross positioning. Robotic tests demonstrated the mechanical fitness of the prototype while an in vitro surgical sclerectomy was performed to demonstrate functionality of the approach. PMID:19377152

  16. Factors affecting polyamide prototypes design of Albedo dosemeters

    International Nuclear Information System (INIS)

    This work studies the most important factors which affect the response of albedo neutron dosemeters containing LiF TLDs with the aim to improve their sensitivity. It includes tests of thickness and shape of the polyamide moderator body prototypes, albedo window diameter and TLD position inside the moderator. Analyzing the results, an albedo neutron dosemeter prototype, B4C covered, was developed. The prototype has a response three times higher than the albedo dosemeter now in use in Brazil. (author)

  17. Clustering of drinker prototype characteristics: what characterizes the typical drinker?

    Science.gov (United States)

    van Lettow, Britt; Vermunt, Jeroen K; de Vries, Hein; Burdorf, Alex; van Empelen, Pepijn

    2013-08-01

    Prototypes (social images) have been shown to influence behaviour, which is likely to depend on the type of image. Prototype evaluation is based on (un)desirable characteristics related to that image. By an elicitation procedure we examined which adjectives are attributed to specific drinker prototypes. In total 149 young Dutch adults (18-25 years of age) provided adjectives for five drinker prototypes: abstainer, moderate drinker, heavy drinker, tipsy, and drunk person. Twenty-three unique adjectives were found. Multilevel latent class cluster analysis revealed six adjective clusters, each with unique and minor overlapping adjectives: 'negative, excessive drinker,' 'moderate, responsible drinker,' 'funny tipsy drinker,' 'determined abstainer cluster,' 'uncontrolled excessive drinker,' and 'elated tipsy cluster.' In addition, four respondent classes were identified. Respondent classes showed differences in their focus on specific adjective clusters. Classes could be labelled 'focus-on-control class,' 'focus-on-hedonism class,' 'contrasting-extremes-prototypes class,' and 'focus-on-elation class.' Respondent classes differed in gender, educational level and drinking behaviour. The results underscore the importance to differentiate between various prototypes and in prototype adjectives among young adults: subgroup differences in prototype salience and relevance are possibly due to differences in adjective labelling. The results provide insights into explaining differences in drinking behaviour and could potentially be used to target and tailor interventions aimed at lowering alcohol consumption among young adults via prototype alteration. PMID:23848388

  18. Design of Object-based Information System Prototype

    Directory of Open Access Journals (Sweden)

    Suhyeon Yoo

    2014-06-01

    Full Text Available Researchers who use science and technology information were found to ask an information service in which they can excerpt the contents they needed, rather than using the information at article level. In this study, we micronized the contents of scholarly articles into text, image, and table and then constructed a micro-content DB to design a new information system prototype based on this micro-content. After designing the prototype, we performed usability test for this prototype so as to confirm the usefulness of the system prototype. We expect that the outcome of this study will fulfill the segmented and diversified information need of researchers.

  19. Theoretical and Experimental Study on Thermoelectric Properties of Ba8TM x Ga y Ge46- x- y (TM = Zn, Cu, Ag) Type I Clathrates

    Science.gov (United States)

    Leszczynski, Juliusz; Kolezynski, Andrzej; Juraszek, Jarosław; Wojciechowski, Krzysztof

    2016-10-01

    In the type I clathrates Ba8TM x Ga y Ge46- x- y (TM = group 10 to 12 elements) where some of the Ge framework atoms are substituted by Zn, Cu or Ag, the transition-metal elements prefer to occupy the 6 c site. Preliminary band-structure calculations showed that this substitution implies modification of the electronic bands in the vicinity of the energy gap. By appropriate tailoring of the band structure, improved thermoelectric properties can be obtained. More detailed full-potential linearized augmented plane wave (FP-LAPW) method calculations within density functional theory (DFT) were performed using the WIEN2k package for compositions where the transition element TM fully occupies the 6 c site. Additional analysis of the properties of the electron density topology within Bader's atoms-in-molecules approach was carried out to study the chemical bonding in intermetallic clathrates. To verify the theoretical predictions, polycrystalline samples of the type I clathrates Ba8TM x Ga y Ge46- x- y (TM = Zn, Cu, Ag) modified by transition-metal element substitution for Ge were obtained. The samples were characterized using powder x-ray diffraction analysis, scanning electron microscopy, and energy-dispersive x-ray spectroscopy. The electrical conductivity, Seebeck coefficient, and thermal conductivity were measured in the temperature range from 320 K to 720 K. Several models were used to fit the experimental results for the electronic transport properties and to estimate the energy gap. Vacancies at the Ge site were considered responsible for deviations from the desired properties, and appropriate defect equations correlating the vacancies and TM concentration are presented. Finally, the results of DFT calculations are compared with the experiments, showing good agreement with theoretically predicted cell parameters and general observations of the transport properties.

  20. Interface Design of UART and USB in TM1300 PCI-XIO Port%TM1300 PCI-XIO口的UART和USB接口设计

    Institute of Scientific and Technical Information of China (English)

    赵井军; 沈斌

    2004-01-01

    以Philips公司的多媒体数字信号处理器TM1300为硬件核心平台,通过TM1300芯片的PCI-XIO口,经UART芯片ST16C550实现串行通信接口,经USB接口芯片USBN9604实现USB接口,设计方案简洁.实际测试结果表明,通信接口工作稳定.

  1. Tm-shift 基因分型方法在遗传学中的应用%Application of Tm-shift genotyping method in genetic studies

    Institute of Scientific and Technical Information of China (English)

    袁芳; 徐进; 季林丹; 费丽娟; 刘盼盼; 张莉娜

    2012-01-01

    Melting Temperature shift(Tm-shift)是一种新的基因分型方法,主要通过在两条特异性引物 5′端加入不同 长度的 GC 序列,PCR 扩增后根据熔解曲线中产物 Tm 值的差异来完成分型.文章建立了 Tm-shift 法对 2 048 份 样品的 29 个 SNP 进行分型,通过分型成功率、重复检测一致率、测序验证准确度综合评价分型效果.结果显 示,29 个 SNP 中有 27 个可以采用本方法分型,分型成功率为 93.1%.测序验证准确性达到 100%.3 种基因型 阳性标准对照重复检测一致率为 100%; 100 个随机样品重复检测,重复性为 97%.因此,Tm-shift 基因分型法是 一种成本低廉、准确灵敏、稳定可靠、通量灵活、操作简便的基因分型方法,可在遗传学研究中推广应用.%Melting Temperature shift (Tm-shift) is a new genotyping method. With two GC-rich tails of unequal length combined to 5'-terminal of allele-specific primers, genotypes can be determined by the distinct Tms of the PCR products with inspection of a melting curve on the real-time PCR machine. In this study, 29 SNPs were genotyped with 2048 samples by using Tm-shift genotyping method, and the results were assessed by success rate, consistent rate, and accuracy. The results indicated that among 29 SNPs, 27 SNPs could be genotyped by Tm-shift. In other words, the success rate was 93.1%. The accuracy confirmed by direct sequencing was 100%. The consistency was 100% with 3 control samples, and 97% from a replication study in 100 samples. Thus, Tm-shift is a genotyping method with advantages including low cost, high accuracy, stability, reliability, flexible throughput, and easy operation, which can be applied to genetic studies widely.

  2. Consistency of L4 TM absolute calibration with respect to the L5 TM sensor based on near-simultaneous image acquisition

    Science.gov (United States)

    Chander, G.; Helder, D.L.; Malla, R.; Micijevic, E.; Mettler, C.J.

    2007-01-01

    The Landsat archive provides more than 35 years of uninterrupted multispectral remotely sensed data of Earth observations. Since 1972, Landsat missions have carried different types of sensors, from the Return Beam Vidicon (RBV) camera to the Enhanced Thematic Mapper Plus (ETM+). However, the Thematic Mapper (TM) sensors on Landsat 4 (L4) and Landsat 5 (L5), launched in 1982 and 1984 respectively, are the backbone of an extensive archive. Effective April 2, 2007, the radiometric calibration of L5 TM data processed and distributed by the U.S. Geological Survey (USGS) Center for Earth Resources Observation and Science (EROS) was updated to use an improved lifetime gain model, based on the instrument's detector response to pseudo-invariant desert site data and cross-calibration with the L7 ETM+. However, no modifications were ever made to the radiometric calibration procedure of the Landsat 4 (L4) TM data. The L4 TM radiometric calibration procedure has continued to use the Internal Calibrator (IC) based calibration algorithms and the post calibration dynamic ranges, as previously defined. To evaluate the "current" absolute accuracy of these two sensors, image pairs from the L5 TM and L4 TM sensors were compared. The number of coincident image pairs in the USGS EROS archive is limited, so the scene selection for the cross-calibration studies proved to be a challenge. Additionally, because of the lack of near-simultaneous images available over well-characterized and traditionally used calibration sites, alternate sites that have high reflectance, large dynamic range, high spatial uniformity, high sun elevation, and minimal cloud cover were investigated. The alternate sites were identified in Yuma, Iraq, Egypt, Libya, and Algeria. The cross-calibration approach involved comparing image statistics derived from large common areas observed eight days apart by the two sensors. This paper summarizes the average percent differences in reflectance estimates obtained between the

  3. Efficient High Power 2 micron Tm3+-Doped Fiber Laser Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal is for the development of new Tm3+ doped germanate glass fibers for efficient high power 2-micron fiber lasers capable of generating an output power...

  4. Efficient high power 2 micron Tm3+-Doped Fiber Laser Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal is for the development of new Tm3+ doped germanate glass fibers for efficient high power 2 micron fiber lasers capable of generating an output power...

  5. Emergency medicine residents' beliefs about contributing to a Google DocsTM presentation: a survey protocol

    Directory of Open Access Journals (Sweden)

    Patrick Archambault

    2011-07-01

    Conclusion To our knowledge, this study will be the first to use a theory based framework to identify healthcare trainees' salient beliefs concerning their decision whether to contribute to an online collaborative writing project using Google DocsTM.

  6. BOREAS Level-3p Landsat TM Imagery: Geocoded and Scaled At-sensor Radiance

    Science.gov (United States)

    Nickeson, Jaime; Knapp, David; Newcomer, Jeffrey A.; Hall, Forrest G. (Editor); Cihlar, Josef

    2000-01-01

    For BOReal Ecosystem-Atmosphere Study (BOREAS), the level-3p Landsat Thematic Mapper (TM) data were used to supplement the level-3s Landsat TM products. Along with the other remotely sensed images, the Landsat TM images were collected in order to provide spatially extensive information over the primary study areas. This information includes radiant energy, detailed land cover, and biophysical parameter maps such as Fraction of Photosynthetically Active Radiation (FPAR) and Leaf Area Index (LAI). Although very similar to the level-3s Landsat TM products, the level-3p images were processed with ground control information, which improved the accuracy of the geographic coordinates provided. Geographically, the level-3p images cover the BOREAS Northern Study Area (NSA) and Southern Study Area (SSA). Temporally, the four images cover the period of 20-Aug-1988 to 07-Jun-1994. Except for the 07-Jun-1994 image, which contains seven bands, the other three contain only three bands.

  7. Analysis of CMOS Compatible Cu-Based TM-Pass Optical Polarizer

    KAUST Repository

    Ng, Tien Khee

    2012-02-10

    A transverse-magnetic-pass (TM-pass) optical polarizer based on Cu complementary metal-oxide-semiconductor technology platform is proposed and analyzed using the 2-D method-of-lines numerical model. In designing the optimum configuration for the polarizer, it was found that the metal-insulator-metal (MIM) polarizer structure is superior compared to the insulator-metal-insulator polarizer structure due to its higher polarization extinction ratio (PER) and low insertion loss. An optimized MIM TM-pass polarizer exhibits simulated long wavelength pass filter characteristics of > ?1.2 ?m, with fundamental TM 0 and TE 0 mode transmissivity of >70% and <5%, respectively, and with PER ?11.5 dB in the wavelength range of 1.2-1.6 ?m. The subwavelength and submicrometer features of this TM-polarizer are potentially suitable for compact and low power photonics integrated circuit implementation on silicon-based substrates. © 1989-2012 IEEE.

  8. Efficient Tm-Fiber-Pumped Ho:YLF Laser System for Coherent LIDAR Applications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to employ a recently developed, efficient, high-power, heavily-doped Tm:silica-fiber technology as a high-gain fiber pre-amplifier and as a...

  9. Lattice sites and damage annealing of implanted Tm and Er in Si

    CERN Document Server

    Wahl, U; De Wachter, J H; Langouche, G; Marques, J G; Moons, R; Vantomme, A

    1997-01-01

    We have studied the lattice sites of Er in CZ Si single crystals by using conversion electron emission channeling from the isotope $^{167m}$Er (2.28 s) which is the decay product of radioactive $^{167}$Tm (9.25 d). Following 60 keV implantation of $^{167}$Tm at a dose of 4 $\\times 10^{13}$ cm$^{-2}$ and annealing at 600°C, more than 90% of $^{167m}$Er is found close to tetrahedral insterstitial (T) sites. The tetrahedral fraction of $^{167m}$Er decreases considerably after 10 min annealing at 800°C and above. We attribute this to the onset of diffusion of the parent $^{167}$Tm and its trapping at other defects, presumably oxygen atoms or clusters of Tm/Er.

  10. SelectfluorTM: A novel and efficient reagent for the rapid -thiocyanation of ketones

    Indian Academy of Sciences (India)

    Dezhen Wu; Xiaojuan Yang; Liqiang Wu

    2012-07-01

    The direct α-thiocyanation of ketones with ammonium thiocyanate has been achieved using SelectfluorTM under mild and neutral conditions to produce -ketothiocyanates, in excellent yields and with high selectivity.

  11. OPERATING THE WAND AND HERCULES PROTOTYPE SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    K. GRUETZMACHER; ET AL

    2001-01-01

    Two prototype systems for low-density Green is Clean (GIC) waste at Los Alamos National Laboratory (LANL) have been in operation for three years at the Solid Waste Operation's (SWOs) non-destructive assay (NDA) building. The Waste Assay for Nonradioactive Disposal (WAND) and the High Efficiency Radiation Counters for Ultimate Low Emission Sensitivity (HERCULES) are used to verify the waste generator's acceptable knowledge (AK) that low-density waste is nonradioactive. GIC waste includes all non-regulated waste generated in radiological controlled areas (RCAs) that has been actively segregated as ''clean'' (i.e., nonradioactive) through the use of waste generator AK. GIC waste that is verified clean can be disposed of at the Los Alamos County Landfill. It is estimated that 50-90% of the low-density room trash from RCAs at LANL might be free of contamination. To date, with pilot programs at five facilities at LANL, 3000 cubic feet of GIC waste has been verified clean by these two prototype systems. Both the WAND and HERCULES systems are highly sensitive measurement systems optimized to detect very small quantities of common LANL radionuclides. Both of the systems use a set of phoswich scintillation detectors in close proximity to the waste, which have the capability of detecting plutonium-239 concentrations below 3 pCi per gram of low density waste. Both systems detect low-energy x-rays and a broad range of gamma rays (10-2000 keV), while the WAND system also detects high energy beta particles (>100 keV). The WAND system consists of a bank of six shielded detectors which screen low density shredded waste or stacked sheets of paper moving under the detectors in a twelve inch swath on a conveyor belt. The WAND system was developed and tested at the Los Alamos Plutonium Facility in conjunction with instrument system designers from the Los Alamos Safeguards Science and Technology group. The HERCULES system consists of a bank of three

  12. Characterization of Tm{sup 3+} doped TNZL glass laser material

    Energy Technology Data Exchange (ETDEWEB)

    Lachheb, R. [Laboratoire Géoressources, Matériaux, Environnement et Changements Globaux, Faculty of Sciences of Sfax, Sfax University, 3018 Sfax (Tunisia); Otto-Schott-Institut, Jena University, Fraunhoferstrasse 6, 07743 Jena (Germany); Damak, K., E-mail: Kamel.Damak@fss.rnu.tn [Laboratory of Radio Analysis and Environment, Sfax University, ENIS, 3038 Sfax (Tunisia); Assadi, A.A. [Laboratoire Géoressources, Matériaux, Environnement et Changements Globaux, Faculty of Sciences of Sfax, Sfax University, 3018 Sfax (Tunisia); Otto-Schott-Institut, Jena University, Fraunhoferstrasse 6, 07743 Jena (Germany); Herrmann, A. [Otto-Schott-Institut, Jena University, Fraunhoferstrasse 6, 07743 Jena (Germany); Yousef, E. [Department of Physics, Faculty of Sciences, Al Azhar University, Assuit branch, Assuit (Egypt); Department of Physics, Faculty of Sciences, King Khalid University, P. O. Box 9004, Abha (Saudi Arabia); Rüssel, C. [Otto-Schott-Institut, Jena University, Fraunhoferstrasse 6, 07743 Jena (Germany); Maâlej, R. [Laboratoire Géoressources, Matériaux, Environnement et Changements Globaux, Faculty of Sciences of Sfax, Sfax University, 3018 Sfax (Tunisia)

    2015-05-15

    In this paper, a new tellurite glass (85TeO{sub 2}·5.0Nb{sub 2}O{sub 5}·5.0ZnO·5.0LiF) doped with 1 mol% Tm{sub 2}O{sub 3} was prepared by melt-quenching technique. Differential scanning calorimetry (DSC) measurements indicate a good thermal stability, X-ray diffraction patterns show no sign of crystallization. Precise refractive index measurements were performed on five different wavelengths by a prism spectrometer. The optical energy gap, the Sellmeier energy gap and the dispersion energy were estimated. Judd–Ofelt intensity parameters were evaluated in order to obtain electric and magnetic-dipole transition probabilities, branching ratios and radiative lifetimes of several excited states of Tm{sup 3+}. The classical McCumber theory was used to evaluate the emission cross-sections for the {sup 3}F{sub 4}→{sup 3}H{sub 6} transition at a wavelength of around 1.8 µm. The characteristics of down-conversion luminescence in the visible range were studied by exciting Tm{sup 3+} ions into the {sup 1}G{sub 4} level. Furthermore the structure of this glass was analyzed by Raman spectroscopy. - Highlights: • A new thermally stable tellurite glass (TNZL doped 1 mol% Tm{sup 3+}) was synthesized by a melt-quenching method. • A complete Judd–Ofelt spectroscopic evaluation of the TNZL:Tm glass is presented. • A high gain coefficient and emission cross section are obtained for Tm{sup 3+} in TNZL glass in the 1.8 μm region. • The TNZL:Tm glass would be a potential laser operation around 1.8 μm emission. • TNZL:Tm is a good candidate for generate a blue light for color display devices and light emitting diodes.

  13. Cluster K mycobacteriophages: insights into the evolutionary origins of mycobacteriophage TM4.

    Directory of Open Access Journals (Sweden)

    Welkin H Pope

    Full Text Available Five newly isolated mycobacteriophages--Angelica, CrimD, Adephagia, Anaya, and Pixie--have similar genomic architectures to mycobacteriophage TM4, a previously characterized phage that is widely used in mycobacterial genetics. The nucleotide sequence similarities warrant grouping these into Cluster K, with subdivision into three subclusters: K1, K2, and K3. Although the overall genome architectures of these phages are similar, TM4 appears to have lost at least two segments of its genome, a central region containing the integration apparatus, and a segment at the right end. This suggests that TM4 is a recent derivative of a temperate parent, resolving a long-standing conundrum about its biology, in that it was reportedly recovered from a lysogenic strain of Mycobacterium avium, but it is not capable of forming lysogens in any mycobacterial host. Like TM4, all of the Cluster K phages infect both fast- and slow-growing mycobacteria, and all of them--with the exception of TM4--form stable lysogens in both Mycobacterium smegmatis and Mycobacterium tuberculosis; immunity assays show that all five of these phages share the same immune specificity. TM4 infects these lysogens suggesting that it was either derived from a heteroimmune temperate parent or that it has acquired a virulent phenotype. We have also characterized a widely-used conditionally replicating derivative of TM4 and identified mutations conferring the temperature-sensitive phenotype. All of the Cluster K phages contain a series of well conserved 13 bp repeats associated with the translation initiation sites of a subset of the genes; approximately one half of these contain an additional sequence feature composed of imperfectly conserved 17 bp inverted repeats separated by a variable spacer. The K1 phages integrate into the host tmRNA and the Cluster K phages represent potential new tools for the genetics of M. tuberculosis and related species.

  14. Cubic to tetragonal phase transition of Tm3+ doped nanocrystals in oxyfluoride glass ceramics

    OpenAIRE

    Yiming Li; Lijuan Zhao; Yuting Fu; Yahui Shi; Xiaoyu Zhang; Hua Yu

    2016-01-01

    Tm3+ ions doped β-PbF2 nanocrystals in oxyfluoride glass ceramics with different doping concentrations and thermal temperatures are prepared by a traditional melt-quenching and thermal treatment method to investigate the structure and the phase transition of Tm3+ doped nanocrystals. The structures are characterized by X-ray diffraction Rietveld analysis and confirmed with numerical simulation. The phase transitions are proved further by the emission spectra. Both of the doping concentration a...

  15. Evaluation of PetrifilmsTM as a diagnostic test to detect bovine mastitis organisms in Kenya

    OpenAIRE

    Gitau, George K.; Royford M. Bundi; Vanleeuwen, John; Mulei, Charles M.

    2012-01-01

    The study purpose was to validate PetrifilmsTM (3M Microbiology, 2005) against standard culture methods in the diagnosis of bovine mastitis organisms in Kenya. On 128 smallholder dairy cattle farms in Kenya, between June 21, 2010 and August 31, 2010, milk samples from 269 cows that were positive on California Mastitis Test (CMT) were cultured using standard laboratory culture methods and PetrifilmsTM (Aerobic Count and Coliform Count –3M Microbiology, 2005), and results were compared. Staphyl...

  16. 整体出色 HTC EVO DesignTM 4G

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    HTC联合运营商SPrint推出了一款4G智能手机HTC EVO DesignTM 4G,这款手机将配备4英寸高清触摸屏。如今。来自运营商Sprint的官方消息显示,HTC EVO DesignTM 4G已经开始发售。

  17. Broadband topology-optimized photonic crystal components for both TE and TM polarizations

    DEFF Research Database (Denmark)

    Têtu, A.; Kristensen, M.; Frandsen, Lars Hagedorn;

    2005-01-01

    Several planar photonic crystal components topology-optimized for TE-polarized light, including 60º bends, Y-splitters, and 90º bends, have been characterized for the TM polarization. The experimental results are confirmed by finite-difference time-domain calculations. The surprising efficiency...... for TM-polarized light is found and paves the way for photonic crystal components suitable for both polarizations....

  18. TmPrime: fast, flexible oligonucleotide design software for gene synthesis

    OpenAIRE

    Bode, Marcus; Khor, Samuel; Ye, Hongye; Li, Mo-Huang; Ying, Jackie Y.

    2009-01-01

    Herein we present TmPrime, a computer program to design oligonucleotide sets for gene assembly by both ligase chain reaction (LCR) and polymerase chain reaction (PCR). TmPrime offers much flexibility with no constraints on the gene and oligonucleotide lengths. The program divides the long input DNA sequence based on the input desired melting temperature, and dynamically optimizes the length of oligonucleotides to achieve homologous melting temperatures. The output reports the melting temperat...

  19. Continuous-wave operation of a room-temperature Tm: YAP-pumped Ho: YAG laser

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    We report a continuous-wave (CW) 2.1-μm Ho:YAG laser operating at room temperature pumped by a diode-pumped 1.94-?m Tm:YAP laser.The maximum output power of 1.5 W is obtained from Ho:YAG laser,corresponding to Tm-to-Ho slope efficiency of 17.9% and diode-to-He conversion efficiency of 5.6%.

  20. Australian manufacture of Quadramet{sup TM} (Samarium-153 EDTMP)

    Energy Technology Data Exchange (ETDEWEB)

    Wood, N.R.; Whitwell, J. [Australian Nuclear Science and Technology Organisation (ANSTO), Lucas Heights, NSW (Australia). Australian Radioisotopes

    1997-10-01

    Quadramet{sup T} (Samarium-153 EDTMP) has been shown overseas to be potentially useful in the palliation of painful osteoblastic skeletal metastases and has been approved this year for general marketing in the USA. Australian Radioisotopes (ARI) has licensed this product from the Australian patent holders, Dow Chemical. Within the facilities of ARI, a hot cell has been dedicated to this product and fitted out to manufacture it weekly on a cycle related to the operating cycle of the Australian reactor HIFAR. Due to neutron flux limitations of HIFAR, the local formulation has an elemental Samarium content up to 200{mu}g/mL whereas the overseas formulation has a level of 20-46{mu}g/mL. All other specifications of the two products are essentially the same. In 1995 and 1996 a small clinical trial with 19 patients was held which demonstrated that the pharmacokinetic behaviour was also essentially the same by measuring blood clearance rates and skeletal uptake dynamics. Soft tissue uptake was also qualitatively determined. The ARI version is now the subject of an application for general marketing within Australia. Some useful characteristics of this agent are: almost complete excretion or fixation in the skeleton within 6 hours, rapid onset of clinical effect, applicability in most cases where an abnormal diagnostic bone scan correlates with painful sites, dosage can be tailored to individual patient uptake due to easy dose measurement and retreatment is quite possible. The use of this class of agents in pain palliation continues to increase. Australian manufacture of Quadramet{sup TM} provides a further option in the management of these difficult cases

  1. Australian manufacture of QuadrametTM (Samarium-153 EDTMP)

    International Nuclear Information System (INIS)

    QuadrametT (Samarium-153 EDTMP) has been shown overseas to be potentially useful in the palliation of painful osteoblastic skeletal metastases and has been approved this year for general marketing in the USA. Australian Radioisotopes (ARI) has licensed this product from the Australian patent holders, Dow Chemical. Within the facilities of ARI, a hot cell has been dedicated to this product and fitted out to manufacture it weekly on a cycle related to the operating cycle of the Australian reactor HIFAR. Due to neutron flux limitations of HIFAR, the local formulation has an elemental Samarium content up to 200μg/mL whereas the overseas formulation has a level of 20-46μg/mL. All other specifications of the two products are essentially the same. In 1995 and 1996 a small clinical trial with 19 patients was held which demonstrated that the pharmacokinetic behaviour was also essentially the same by measuring blood clearance rates and skeletal uptake dynamics. Soft tissue uptake was also qualitatively determined. The ARI version is now the subject of an application for general marketing within Australia. Some useful characteristics of this agent are: almost complete excretion or fixation in the skeleton within 6 hours, rapid onset of clinical effect, applicability in most cases where an abnormal diagnostic bone scan correlates with painful sites, dosage can be tailored to individual patient uptake due to easy dose measurement and retreatment is quite possible. The use of this class of agents in pain palliation continues to increase. Australian manufacture of QuadrametTM provides a further option in the management of these difficult cases

  2. Luminescence Properties of Eu/Tm/Tb-doped Borosilicate Glass%Eu/Tm/Tb掺杂硼硅酸盐玻璃的发光性能

    Institute of Scientific and Technical Information of China (English)

    石冬梅; 赵营刚

    2016-01-01

    Eu/Tm/Tb-doped singly, doubly and triply borosilicate glasses were prepared using a conventional melting-quenching method. The luminescent properties of Eu/Tm/Tb-doped samples under the UV excitation were investigated in detail by measuring the excitation and emission spectra and calculating CIE chromaticity coordinates. The results show that the sharp emission peak centered at 459 nm originating from 1 D2→3 F4 of Tm3+ is observed, and the characteristic emission intensity centered at 437 nm ascribing to the broad peak of Eu2+, 589 nm( 5 D0→7 F1 ) and 612 nm( 5 D0→7 F2 ) of Eu3+ is reduced due to the energy transfer from Eu3+,Eu2+ to Tm3+ ion. Red, green and blue light can be observed in Eu/Tm/Tb-doped triply samples simultaneously under the excitation of 377 nm. The luminescent intensity and color of borosilicate glasses might be changed by adjusting Eu2 O3 content, and the sample with CIE chromaticity coordinates(0. 33, 0. 386 7)are obtained.%采用熔融淬冷法制备了性能优越的Eu/Tm/Tb单掺、双掺和三掺的硼硅酸盐玻璃。测试了样品的激发和发射光谱,计算了CIE色坐标,研究了紫外激发下Eu/Tm/Tb掺杂的硼硅酸盐玻璃的发光性能。结果表明:在361 nm激发下,随着Tm3+加入到Eu2O3掺杂的硼硅酸盐样品中,观察到Tm3+的459 nm(1D2→3F4)锐线特征发射峰,同时由于Eu3+,Eu2+→Tm3+的能量传递的存在降低了Eu2+的437 nm宽带峰及Eu3+的589 nm(5 D0→7 F1)和612 nm(5 D0→7 F2)的特征发射峰强度。在377 nm激发下,Eu/Tm/Tb三掺样品能够同时出现红、绿和蓝光。调节 Eu2O3的含量能有效改变发光玻璃的发光强度和颜色,最终得到色坐标为(0.33,0.3867)的发光玻璃。

  3. Enhanced mid-IR emission in Yb3+-Tm3+ co-doped oxyfluoride glass ceramics

    International Nuclear Information System (INIS)

    Graphical abstract: Display Omitted Research highlights: → Tm3+ and Yb3+ ions had been enriched in the nanocrystals of the glass ceramics. → Mid-IR luminescence intensity of the glass ceramics was enhanced. → Judd-Ofelt theory was used to calculate optical parameters. - Abstract: Tm3+-Yb3+ co-doped transparent oxyfluoride glass ceramics were prepared through thermal treatment of the as-prepared glasses. The precipitation of nanocrystals and the incorporation of Tm3+ and Yb3+ into the nanocrystals were confirmed by X-ray diffraction and absorption spectra. Based on the Judd-Ofelt theory, the J-O parameters Ωλ (λ = 2, 4, 6), spontaneous radiative transition rates, radiative lifetimes and fluorescence branching ratios of Tm3+ in both as-prepared glasses and glass ceramics were calculated. Intense mid-IR emission and upconversion luminescence in the Tm3+ and Yb3+ co-doped glass ceramics were observed under 980 nm excitation. Especially, compared with that of the as-prepared glasses, mid-IR luminescence intensity of Tm3+ in the glass ceramics was greatly enhanced. Desirable spectroscopic characteristics suggest that these oxyfluoride glass ceramics may be promising mid-IR laser active medium.

  4. tmRNA-SmpB: a journey to the centre of the bacterial ribosome.

    Science.gov (United States)

    Weis, Félix; Bron, Patrick; Giudice, Emmanuel; Rolland, Jean-Paul; Thomas, Daniel; Felden, Brice; Gillet, Reynald

    2010-11-17

    Ribosomes mediate protein synthesis by decoding the information carried by messenger RNAs (mRNAs) and catalysing peptide bond formation between amino acids. When bacterial ribosomes stall on incomplete messages, the trans-translation quality control mechanism is activated by the transfer-messenger RNA bound to small protein B (tmRNA-SmpB ribonucleoprotein complex). Trans-translation liberates the stalled ribosomes and triggers degradation of the incomplete proteins. Here, we present the cryo-electron microscopy structures of tmRNA-SmpB accommodated or translocated into stalled ribosomes. Two atomic models for each state are proposed. This study reveals how tmRNA-SmpB crosses the ribosome and how, as the problematic mRNA is ejected, the tmRNA resume codon is placed onto the ribosomal decoding site by new contacts between SmpB and the nucleotides upstream of the tag-encoding sequence. This provides a structural basis for the transit of the large tmRNA-SmpB complex through the ribosome and for the means by which the tmRNA internal frame is set for translation to resume.

  5. Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo.

    Science.gov (United States)

    Zhu, Wei; Gramlich, Oliver W; Laboissonniere, Lauren; Jain, Ankur; Sheffield, Val C; Trimarchi, Jeffrey M; Tucker, Budd A; Kuehn, Markus H

    2016-06-21

    Glaucoma is a common cause of vision loss or blindness and reduction of intraocular pressure (IOP) has been proven beneficial in a large fraction of glaucoma patients. The IOP is maintained by the trabecular meshwork (TM) and the elevation of IOP in open-angle glaucoma is associated with dysfunction and loss of the postmitotic cells residing within this tissue. To determine if IOP control can be maintained by replacing lost TM cells, we transplanted TM-like cells derived from induced pluripotent stem cells into the anterior chamber of a transgenic mouse model of glaucoma. Transplantation led to significantly reduced IOP and improved aqueous humor outflow facility, which was sustained for at least 9 wk. The ability to maintain normal IOP engendered survival of retinal ganglion cells, whose loss is ultimately the cause for reduced vision in glaucoma. In vivo and in vitro analyses demonstrated higher TM cellularity in treated mice compared with littermate controls and indicated that this increase is primarily because of a proliferative response of endogenous TM cells. Thus, our study provides in vivo demonstration that regeneration of the glaucomatous TM is possible and points toward novel approaches in the treatment of this disease. PMID:27274060

  6. Environmental Resources Analysis System, A Prototype DSS

    Science.gov (United States)

    Flug, M.; Campbell, S.G.; Bizier, P.; DeBarry, P.

    2003-01-01

    Since the 1960's, an increase in the public's environmental ethics, federal species preservation, water quality protection, and interest in free flowing rivers have evolved to the current concern for stewardship and conservation of natural resources. This heightened environmental awareness creates an appetite for data, models, information management, and systematic analysis of multiple scientific disciplines. A good example of this information and analysis need resides in the Green and Yampa Rivers, tributary to the Upper Colorado River. These rivers are home to endangered native fish species including the pikeminnow and razorback sucker. Two dams, Fontenelle and Flaming Gorge, impound the Green River headwaters. The respective reservoirs store water supplies as well as generate hydropower. Conversely, the Yampa River is considered unregulated and encompasses most of Dinosaur National Monument. Recreation is highly regarded on both rivers including fishing, whitewater rafting, and aesthetic values. Vast areas of irrigated agriculture, forestry, and mineral extraction also surround these rivers. To address this information need, we developed a prototype Environmental Resources Analysis System (ERAS) spreadsheet-based decision support system (DSS). ERAS provides access to historic data sets, scientific information, statistical analysis, model outputs, and comparative methods all in a familiar and user-friendly format. This research project demonstrates a simplified decision support system for use by a diverse mix of resource managers, special interest groups, and individuals concerned about the sustainability of the Green and Yampa River ecosystem.

  7. Simplified prototyping of perfusable polystyrene microfluidics

    Science.gov (United States)

    Tran, Reginald; Ahn, Byungwook; R. Myers, David; Qiu, Yongzhi; Sakurai, Yumiko; Moot, Robert; Mihevc, Emma; Trent Spencer, H.; Doering, Christopher; A. Lam, Wilbur

    2014-01-01

    Cell culture in microfluidic systems has primarily been conducted in devices comprised of polydimethylsiloxane (PDMS) or other elastomers. As polystyrene (PS) is the most characterized and commonly used substrate material for cell culture, microfluidic cell culture would ideally be conducted in PS-based microsystems that also enable tight control of perfusion and hydrodynamic conditions, which are especially important for culture of vascular cell types. Here, we report a simple method to prototype perfusable PS microfluidics for endothelial cell culture under flow that can be fabricated using standard lithography and wet laboratory equipment to enable stable perfusion at shear stresses up to 300 dyn/cm2 and pumping pressures up to 26 kPa for at least 100 h. This technique can also be extended to fabricate perfusable hybrid PS-PDMS microfluidics of which one application is for increased efficiency of viral transduction in non-adherent suspension cells by leveraging the high surface area to volume ratio of microfluidics and adhesion molecules that are optimized for PS substrates. These biologically compatible microfluidic devices can be made more accessible to biological-based laboratories through the outsourcing of lithography to various available microfluidic foundries. PMID:25379106

  8. Prototype models for the MOIRA computerised system

    Energy Technology Data Exchange (ETDEWEB)

    Monte, Luigi [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dipt. Ambiente; Hakanson, Lars [Uppsala, Univ. (Sweden). Institute of Earth Sciences; Brittain, John [Oslo, Univ. (Norway). Zoological Museum

    1997-06-01

    The main aim of the present report is to describe selected models and the principles of the Decision Analysis theory that will be applied to develop the model-based computerised system `MOIRA`. A dose model and a model for predicting radiocaesium migration in lakes and the effects of countermeasures to reduce the contamination levels in the components of lacustrine system are described in detail. The principles for developing prototype models for predicting the migration of {sup 90}Sr in lake abiotic and biotic components are discussed. The environmental models described in the report are based on the use of `collective parameters` which due to mutual compensation effects of different phenomena occurring in complex systems, show low variability when the environmental conditions change. Use of such `collective parameters` not only increases the predictive power of the models, but also increases the practical applicability of the model. Among the main results described in the report, the development of an objective hierarchy table for evaluating the effectiveness of a countermeasure when the economic, social and ecological impacts are accounted for, deserves special attention.

  9. Prototype fast breeder reactor main options

    International Nuclear Information System (INIS)

    Fast reactor programme gets importance in the Indian energy market because of continuous growing demand of electricity and resources limited to only coal and FBR. India started its fast reactor programme with the construction of 40 MWt Fast Breeder Test Reactor (FBTR). The reactor attained its first criticality in October 1985. The reactor power will be raised to 40 MWt in near future. As a logical follow-up of FBTR, it was decided to build a prototype fast breeder reactor, PFBR. Considering significant effects of capital cost and construction period on economy, systematic efforts are made to reduce the same. The number of primary and secondary sodium loops and components have been reduced. Sodium coolant, pool type concept, oxide fuel, 20% CW D9, SS 316 LN and modified 9Cr-1Mo steel (T91) materials have been selected for PFBR. Based on the operating experience, the integrity of the high temperature components including fuel and cost optimization aspects, the plant temperatures are recommended. Steam temperature of 763 K at 16.6 MPa and a single TG of 500 MWe gross output have been decided. PFBR will be located at Kalpakkam site on the coast of Bay of Bengal. The plant life is designed for 30 y and 75% load factor. In this paper the justifications for the main options chosen are given in brief. (author). 2 figs, 2 tabs

  10. Novel photon detectors for focusing DIRC prototype

    Energy Technology Data Exchange (ETDEWEB)

    Field, C.; Hadig, T.; Jain, M.; Leith, D.W.G.S.; Mazaheri, G.; Ratcliff, B.N.; Schwiening, J.; Va' vra, J. E-mail: jjv@slac.stanford.edu

    2004-02-01

    For present BaBar DIRC, the Cherenkov angular resolution is dominated by three contributions - the chromatic error, bar thickness and pixel size. We have designed the Focusing DIRC prototype, which potentially can reduce the chromatic error by a precise timing in the range of 50-100 ps per photon, and the bar thickness by a focusing mirror. This paper describes two novel photon detectors, which are candidates for this type of concept: Hamamatsu 64-channel multi-anode Flat Panel H-8500 PMTs and Burle 64-channel micro-channel plate MCP-PMTs. The detectors were tested with a PiLas laser diode light pulse providing 35 ps FWHM timing resolution. A single-photon timing resolution of (1) {sigma}{approx}120-140 ps was achieved with the Hamamatsu PMTs, and (2) {sigma}{approx}55 ps with the Burle MCP-PMTs. To achieve the good timing resolution results, we have developed a new fast amplifier and a constant-fraction discriminator. We have also developed a computer-controlled scanning setup, which allows a detailed study of the relative efficiency response to single photons.

  11. Novel photon detectors for focusing DIRC prototype

    Science.gov (United States)

    Field, C.; Hadig, T.; Jain, M.; Leith, D. W. G. S.; Mazaheri, G.; Ratcliff, B. N.; Schwiening, J.; Va'vra, J.

    2004-02-01

    For present BaBar DIRC, the Cherenkov angular resolution is dominated by three contributions—the chromatic error, bar thickness and pixel size. We have designed the Focusing DIRC prototype, which potentially can reduce the chromatic error by a precise timing in the range of 50-100 ps per photon, and the bar thickness by a focusing mirror. This paper describes two novel photon detectors, which are candidates for this type of concept: Hamamatsu 64-channel multi-anode Flat Panel H-8500 PMTs and Burle 64-channel micro-channel plate MCP-PMTs. The detectors were tested with a PiLas laser diode light pulse providing 35 ps FWHM timing resolution. A single-photon timing resolution of (1) σ˜120-140 ps was achieved with the Hamamatsu PMTs, and (2) σ˜55 ps with the Burle MCP-PMTs. To achieve the good timing resolution results, we have developed a new fast amplifier and a constant-fraction discriminator. We have also developed a computer-controlled scanning setup, which allows a detailed study of the relative efficiency response to single photons.

  12. Rapid Prototyping Modules for Remote Engineering Applications

    Directory of Open Access Journals (Sweden)

    Karsten Henke

    2008-07-01

    Full Text Available This contribution describes the concept and implementation for an integration of microcontroller and FPGA based Rapid Prototyping modules into a Remote Lab system. This implementation enables a Web-based access to electro-mechanical models. A student uploads a source file implementation to the Remote Lab server in order to test an implementation directly within a hardware environment. The Remote Lab server offers the interfaces to integrate specific project and hardware plug-ins. These plug-ins access a hardware specific software environment to automatically compile and program the resulting firmware. To stimulate this design, the Remote Lab server exchanges digital signals via a serial interface. To allow the student to compare architectures of different designs using the same hardware model, a specific controller (using the Remote Lab interface can be selected. For this, an IP-based multiplexer provides the control connection between the respective controller and the hardware model. In our contribution we would like to give examples of such a complex design task and how the students can use different tools during several design steps.

  13. Performance of the GRETA prototype detectors

    CERN Document Server

    Vetter, K; Lee, I Y; Clark, R M; Cromaz, M; Deleplanque, M A; Diamond, R M; Fallon, P; Lane, G J; Macchiavelli, A O; Maier, M R; Stephens, F S; Svensson, C E; Yaver, H

    2000-01-01

    A working, two-dimensionally segmented Ge detector is one of the crucial elements in the development of GRETA - a next-generation 4 pi germanium detector array that uses three-dimensional positions and energies to of individual interactions of gamma rays in the detector to reconstruct the full energies and direction vectors of the individual gamma rays by employing tracking algorithms. The three-dimensional position and the energy of interactions will be determined by using a two-dimensionally segmented Ge detector along with pulse-shape analysis of the signals. The current prototype is a 36-fold segmented HP-Ge detector in a closed-ended coaxial geometry. Preamplifiers with a compact design, low noise, and very good response properties have been built and implemented. An integrated noise level of about 5 keV has been measured for the segment channels. The average energy resolution of this detector was measured to be 1.14 and 1.93 keV at 60 and 1332 keV, respectively. Using pulse-shape analysis, a three-dimen...

  14. AC Losses of Prototype HTS Transmission Cables

    Energy Technology Data Exchange (ETDEWEB)

    Demko, J.A.; Dresner, L.; Hughey, R.L.; Lue, J.W.; Olsen, S.K.; Sinha, U.; Tolbert, J.C.

    1998-09-13

    Since 1995 Southwire Company and Oak Ridge National Laboratory (ORNL) have jointly designed, built, and tested nine, l-m long, high temperature superconducting (HTS) transmission cable prototypes. This paper summarizes the AC loss measurements of five of the cables not reported elsewhere, and compares the losses with each other and with theory developed by Dresner. Losses were measured with both a calorimetric and an electrical technique. Because of the broad resistive transition of the HTS tapes, the cables can be operated stably beyond their critical currents. The AC losses were measured in this region as well as below critical currents. Dresner's theory takes into account the broad resistive transition of the HTS tapes and calculates the AC losses both below and above the critical current. The two sets of AC 10SS data agree with each other and with the theory quite welL In particular, at low currents of incomplete penetration, the loss data agree with the theoretical prediction of hysteresis loss based on only the outer two Iayers carrying the total current.

  15. Sparse distributed memory prototype: Principles of operation

    Science.gov (United States)

    Flynn, Michael J.; Kanerva, Pentti; Ahanin, Bahram; Bhadkamkar, Neal; Flaherty, Paul; Hickey, Philip

    1988-01-01

    Sparse distributed memory is a generalized random access memory (RAM) for long binary words. Such words can be written into and read from the memory, and they can be used to address the memory. The main attribute of the memory is sensitivity to similarity, meaning that a word can be read back not only by giving the original right address but also by giving one close to it as measured by the Hamming distance between addresses. Large memories of this kind are expected to have wide use in speech and scene analysis, in signal detection and verification, and in adaptive control of automated equipment. The memory can be realized as a simple, massively parallel computer. Digital technology has reached a point where building large memories is becoming practical. The research is aimed at resolving major design issues that have to be faced in building the memories. The design of a prototype memory with 256-bit addresses and from 8K to 128K locations for 256-bit words is described. A key aspect of the design is extensive use of dynamic RAM and other standard components.

  16. Design Prototypes: A Knowledge Representation Schema for Design

    OpenAIRE

    Gero, John S.

    1990-01-01

    This article begins with an elaboration of models of design as a process. It then introduces and describes a knowledge representation schema for design called design prototypes. This schema supports the initiation and continuation of the act of designing. Design prototypes are shown to provide a suitable framework to distinguish routine, innovative, and creative design.

  17. Study of prototype sensors for the Upstream Tracker Upgrade

    CERN Document Server

    Abba, Andrea; Blusk, Steven R.; Bursche, Albert; Davis, Adam; Dendek, Adam Mateusz; Dey, Biplab; Ely, Scott Edward; Forshaw, Dean Charles; Fu, Jinlin; Kelsey, Matthew Jordan; Lionetto, Federica; Manning Jr, Peter Michael; Mountain, Ray; Neri, Nicola; Papula, Alana Leigh; Petruzzo, Marco; Pikies, Malgorzata Maria; Rudolph, Matthew Scott; Sokoloff, Michael David; Stone, Sheldon; Szumlak, Tomasz; Wang, Jianchun

    2016-01-01

    Three testbeams were carried out in 2015 to test the performance of prototype sensors for the Upstream Tracker. Two of the testbeams were devoted to studying full size n-in-p sensors, and one was devoted to testing mini-sensors, all from Hamamatsu. Results on the performance of these Upstream Tracker sensor prototypes are presented.

  18. The Prototype Theory and the Simple Present Tense Teaching

    Institute of Scientific and Technical Information of China (English)

    袁昌玲; 杨唐峰

    2016-01-01

    The prototype theory has been widely applied to the language teaching. In this paper, the author analyzes the relations between different uses of the simple present tense from the perspective of the prototype theory, hoping to help students understand this tense better and promote the application of this theory to English tense teaching.

  19. Improving traceability to the international prototype of the kilogram

    Science.gov (United States)

    Nielsen, Lars; Davis, Richard S.; Barat, Pauline

    2015-08-01

    Until a new definition of the kilogram has been adopted, the SI unit of mass remains defined in terms of an artefact, the international prototype of the kilogram K, which is not readily available for regular recalibration of BIPM prototypes used for the calibration of national prototypes. Since 1889 the working hypothesis has been that the platinum-iridium prototypes are stable mass standards, although mass comparisons indicate that this is not entirely true. In this paper we present a method for improving metrological traceability to the international prototype K by modelling the change in mass of prototypes over time and evaluate the model parameters by a weighted least squares adjustment. The method has been applied to comparisons between 18 prototypes performed at the BIPM in the period 1889-2009. The mass values predicted by the model are compared to the mass values assigned by BIPM in the period 1992-2009 and to results of the Extraordinary Calibrations performed at BIPM in 2014 using the international prototype K as reference standard.

  20. Virtual Prototyping through Co-simulation of a Cartesian Plotter

    NARCIS (Netherlands)

    Groothuis, M.A.; Damstra, A.S.; Broenink, J.F.

    2008-01-01

    This paper shows a model-based design trajectory for the development of real-time embedded control software using virtual prototyping. As a test case, a Cartesian plotter is designed. Functional correctness of the plotter software has been ensured by means of co-simulation using a virtual prototype

  1. A Prototype HTML Training System for Graphic Communication Majors

    Science.gov (United States)

    Runquist, Roger L.

    2010-01-01

    This design research demonstrates a prototype content management system capable of training graphic communication students in the creation of basic HTML web pages. The prototype serve as a method of helping students learn basic HTML structure and commands earlier in their academic careers. Exposure to the concepts of web page creation early in…

  2. Construction of a drift chamber prototype for the CMS experiment

    International Nuclear Information System (INIS)

    General design features of a small size drift chamber prototype are described in this report. Prototype construction has taken place at CIEMAT and we explain in detail the assembly procedure. This activity is part of a long term project to mass produce chambers for the muon barrel detector of the CMS experiment which will be installed at CERN. (Author)

  3. Magnetic switching, final chapter, Book I: the ATA upgrade prototype

    Energy Technology Data Exchange (ETDEWEB)

    Birx, D.; Cook, E.; Hawkins, S.; Poor, S.; Reginato, L.; Schmidt, J.; Smith, M.W.

    1983-03-22

    Efforts directed at finding a 10 kHz switch to replace the current 1 kHz gas blown spark gap have culminated in a prototype for an upgrade of ATA. The design and performance of this prototype as well as possible options and recommendations concerning an eventual upgrade are described. 4 references, 9 figures.

  4. Analyzing opportunities for using interactive augmented prototyping in design practice

    NARCIS (Netherlands)

    Verlinden, J.C.; Horvath, I.

    2009-01-01

    The use of tangible objects is paramount in industrial design. Throughout the design process physical prototypes are used to enable exploration, simulation, communication, and specification of designs. Although much is known about prototyping skills and technologies, the reasons why and how such mod

  5. Clustering of drinker prototype characteristics: What characterizes the typical drinker?

    NARCIS (Netherlands)

    Lettow, B. van; Vermunt, J.K.; Vries, H. de; Burdorf, A.; Empelen, P. van

    2013-01-01

    Prototypes (social images) have been shown to influence behaviour, which is likely to depend on the type of image. Prototype evaluation is based on (un)desirable characteristics related to that image. By an elicitation procedure we examined which adjectives are attributed to specific drinker prototy

  6. Test Beam Results Obtained with the Q4 Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Aguilar-Benitez, M.; Alberdi, J.; Cerrada, M.; Colino, N.; Daniel, M.; Fouz, M. c.; Marin, J.; Mocholi, J.; Oller, J. C.; Puerta, J.; Romero, L.; Salicio, J. M.

    2000-07-01

    A prototype of the CMS Barrel Muon Detector incorporating all the features of the final chambers was built at CIEMAT using the mass production assembly procedures and tools. The performance of this prototype was studied in a muon test beam at CERN and the results obtained are presented here. (Author)

  7. Prototype Theory and Its Implication into English Vocabulary Teaching

    Institute of Scientific and Technical Information of China (English)

    郑禄娟; 张锐

    2015-01-01

    Prototype is the cognitive reference point that human beings use to categorize the world.It is the best and most typical member in the category while the other members of the category are centered on it.Guided by prototype theory,this paper will discuss some implications to English vocabulary teaching.

  8. Students' Drinker Prototypes and Alcohol Use in a Naturalistic Setting

    NARCIS (Netherlands)

    Spijkerman, R.; Larsen, H.; Gibbons, F.X.; Engels, R.C.M.E.

    2010-01-01

    Background: Perceptions about the type of people who drink, also referred to as drinker prototypes May strengthen Young people's motivation to engage in alcohol use. Previous research has shown that drinker prototypes are related to alcohol consumption in both adolescents and young adults. However.

  9. Enhancements to ASHRAE Standard 90.1 Prototype Building Models

    Energy Technology Data Exchange (ETDEWEB)

    Goel, Supriya; Athalye, Rahul A.; Wang, Weimin; Zhang, Jian; Rosenberg, Michael I.; Xie, YuLong; Hart, Philip R.; Mendon, Vrushali V.

    2014-04-16

    This report focuses on enhancements to prototype building models used to determine the energy impact of various versions of ANSI/ASHRAE/IES Standard 90.1. Since the last publication of the prototype building models, PNNL has made numerous enhancements to the original prototype models compliant with the 2004, 2007, and 2010 editions of Standard 90.1. Those enhancements are described here and were made for several reasons: (1) to change or improve prototype design assumptions; (2) to improve the simulation accuracy; (3) to improve the simulation infrastructure; and (4) to add additional detail to the models needed to capture certain energy impacts from Standard 90.1 improvements. These enhancements impact simulated prototype energy use, and consequently impact the savings estimated from edition to edition of Standard 90.1.

  10. Comparative analysis of the GoldeneyeTM 20A kit and SinofilerTM kits%GoldeneyeTM20A和SinofilerTM试剂盒的比较研究

    Institute of Scientific and Technical Information of China (English)

    赵金玲; 贾菲; 郭飞; 于蛟; 赵斌; 姜先华

    2013-01-01

    目的 比较GoldeneyeTM 20A和SinofilerTM试剂盒的技术性能指标.方法 从灵敏度、杂合等位基因峰高均衡性、耐受性、混合样本检测及等位基因分型结果5个方面对GoldeneyeTM 20A试剂盒和SinofilerTM试剂盒进行了比较.结果 两种试剂盒的检测灵敏度值均为125pg;两种试剂盒在不同模板量扩增得到的杂合子平均峰高比值相近;GoldeneyeTM 20A试剂盒对血红素抑制剂的耐受性略好于SinofilerTM试剂盒,当血红素含量为80μmol/L也可以得到完整的分型结果;两种试剂盒对7∶1和1:7比例的混合样本都能得到主要与次要成分的完整等位基因分型结果.同一样本两种试剂盒在15个共有基因座上的分型结果完全相同.结论 两种试剂盒的性能无明显差别,均能满足检验需要.GodeneyeTM 20A试剂盒只需一次检验即可得到19个常染色体STR基因座和1个性别基因座的分型信息,在法庭科学检验和DNA数据库建设中具有较高的应用价值.%Objective To conduct a comparative analysis using the GoldeneyeTM 20A and SinofilerTM kits.Methods Comparison on the sensitivity,average peak height ratio (PHR) for heterozygotes,stability,ability to genotype mixtures and genotyping results between the two kits were performed.Results For both kits,full profiles were routinely generated from as low as 125pg DNA.The average PHR for heterozygotes of the two kits at each mass of DNA amplified was balanced and similar.The GoldeneyeTM 20A system exhibited better robustness than the SinofilerTM kit in genotyping haematin-contained samples,and it could obtained full profiles when haematin concentration was 80μmol/L.Both kits were able to obtain primary and secondary components of a complete genotypes for 7∶1 and 1∶7 ratio of mixed samples.In addition,the typing results for the same samples with the two kits were consistent completely.Conclusions There is no significant difference in the performance of the two kits

  11. Opioid-induced redistribution of 6TM and 7TM μ opioid receptors: A hypothesized mechanistic facilitator model of opioid-induced hyperalgesia.

    Science.gov (United States)

    Wang, Wei; Wang, Yan; Zhang, Wei; Jin, Xiaoju; Liu, Yusheng; Xu, Shiqin; Lei, Liming; Shen, Xiaofeng; Guo, Xirong; Xia, Xiaoqiong; Wang, Fuzhou

    2016-08-01

    Opioids are still the most popular form of pain treatment, but many unavoidable side effects make opioids a big challenge in effective pain management. Opioid-induced hyperalgesia (OIH), a paradoxical phenomenon, portrays an increased sensitivity to harmful stimuli caused by opioid exposure. Changes in the neural modulation are considered a major contributor to the development of OIH. Activation of opioid receptors (ORs) and corresponding downstream molecules are the vital composition of functional performance of opioids. Increasing interests were proposed of the interaction between ORs and other neural transmitter systems such as glutamatergic, GABAergic and adrenergic ones to the genesis of OIH. G protein coupled μ-opioid receptor (MOR) was studied comprehensively on its role in the development of OIH. In addition to the relationship between MOR and other neurotransmitter receptors, a new intracellular MOR that has six transmembrane (6TM) domains was identified, and found to perform a pro-nociceptive task in contrast to the counterpart 7TM isoform. A mechanistic model of OIH in which both 6TM and 7TM MORs undergoing membrane redistribution upon opioid exposure is proposed which eventually facilitates the neurons more sensitive to nociceptive stimulation than that of the preceding opioid exposure.

  12. In vitro screening of reversible and time-dependent inhibition on CYP3A by TM208 and TM209 in rat liver microsomes

    Directory of Open Access Journals (Sweden)

    Miaoran Ning

    2012-04-01

    Full Text Available TM208 and TM209, dithiocarbamate derivatives with potential anti-cancer effects, were evaluated in reversible and time-dependent cytochrome P450 (CYP 3A inhibition assays in rat liver microsomes using testosterone as probe substrate. Both compounds were found to be weak reversible inhibitors and moderate mechanism-based inhibitors of rat CYP3A. For reversible inhibition on rat CYP3A, the Ki values of competitive inhibition model were 12.10±1.75 and 13.94±1.31 μM, respectively. For time-dependent inhibition, the inactivation constants (Kl were 31.93±12.64 and 32.91±15.58 μM, respectively, and the maximum inactivation rates (kinact were 0.03497±0.0069 and 0.07259±0.0172 min−1 respectively. These findings would provide useful in vitro information for future in vivo DDI studies on TM208 or TM209.

  13. New technology for mating disruption and prospects for integration with SIT: ExosexTM and ExolureTM

    International Nuclear Information System (INIS)

    Full text: The Exosex autoconfusion system has been successfully trialed against a variety of insect pests and is now registered for use in certain countries. It differs fundamentally from all other mating disruption systems by contaminating the target pest with electrostatically charged powder formulated with pheromone or other biologically active materials. The method requires only 25 dispensers and less than 100 mg of pheromone per hectare. The mode of action in disrupting mate location, courtship, and mating, may include a variety of effects, all of which contribute to the efficacy of management of the pest in question. The most important are believed to be the following: - False trail following: - Habituation; - Trail masking; - Sensory imbalance; - Inhibition of courtship; - Enhancement of predation and; - Delay of mating. Factors making Exosex autoconfusion such a uniquely powerful technology are demonstrated by the following calculations based on the threshold responsiveness of Cydia pomonella to pheromone. One particle of EntostatTM (wax) powder contains on average 67 femtograms (6.7 x 10 14 g) of formulated pheromone, and there are approximately 1.5 x 1010 particles per gram of powder. One particle resting on the antennae would theoretically release sufficient pheromone to induce habituation of responsiveness to pheromone. Approximately 1,800 particles would constitute an attractive source for a male moth in the field. Hence the contents of one Exosex dispenser are theoretically capable of contaminating around 1 billion male codling moths with enough pheromone to make them attractive sources to other males. The Exosect technology has also given rise to a highly efficient lure and kill method, in which slow-acting chemical insecticides or entomopathogens can be spread throughout a pest population by autodissemination. Both the mating disruption and lure and kill technologies are clearly compatible with SIT, and several new ideas will be presented

  14. DNA解链温度(Tm)不同预测方法的比较%A comparison of different melting temperature (Tm) prediction methods for DNAg

    Institute of Scientific and Technical Information of China (English)

    张艳春; 屈武斌; 卢一鸣; 周扬; 张成岗

    2011-01-01

    目的 寻找最优的DNA解链温度(Tm)预测方法.方法 使用12种Tm值预测方法计算来自文献中348个实测数据的Tm值,将每种方法预测值与实验标准值的差值进行四分位法作图,并计算各方法残差平方和的自然对数,排序后比较12种预测方法的优劣.结果 使用最邻近法并结合SantaLucia 1998热力学参数表和Schildkraut 1965 盐浓度校正公式所预测的Tm值最接近实测数据.结论 最邻近法是最准确的Tm值预测方法,而且当PCR引物的GC含量越接近于50%时,其预测准确率越高.%Objective To find the optimal method for predicting the melting temperature (Tm) of DNA.Methods The Tm value of 348 experiment-derived data from literature was calculated by the 12 Tm prediction methods.The interquartile figure was drawn to show the difference between the predicted Tm values and the experimental benchmark data set, before the natural logarithm of the sum of square (SSQ) was compared between each prediction method and experiment-derived data.Results Our data indicated that the SSQ value obtained by using the "Nearest Neighbor" (NN) model in combination with the thermodynamics table of "SantaLucia 1998" and the salt correctionformula of "Schildkraut 1965" was the minimum one among the 12 Tm prediction methods.Conclusion The NN model is the most accurate and robust method for Tm prediction, especially for the primers with a GC content close to 50%.

  15. A microbased shared virtual world prototype

    Science.gov (United States)

    Pitts, Gerald; Robinson, Mark; Strange, Steve

    1993-01-01

    Virtual reality (VR) allows sensory immersion and interaction with a computer-generated environment. The user adopts a physical interface with the computer, through Input/Output devices such as a head-mounted display, data glove, mouse, keyboard, or monitor, to experience an alternate universe. What this means is that the computer generates an environment which, in its ultimate extension, becomes indistinguishable from the real world. 'Imagine a wraparound television with three-dimensional programs, including three-dimensional sound, and solid objects that you can pick up and manipulate, even feel with your fingers and hands.... 'Imagine that you are the creator as well as the consumer of your artificial experience, with the power to use a gesture or word to remold the world you see and hear and feel. That part is not fiction... three-dimensional computer graphics, input/output devices, computer models that constitute a VR system make it possible, today, to immerse yourself in an artificial world and to reach in and reshape it.' Our research's goal was to propose a feasibility experiment in the construction of a networked virtual reality system, making use of current personal computer (PC) technology. The prototype was built using Borland C compiler, running on an IBM 486 33 MHz and a 386 33 MHz. Each game currently is represented as an IPX client on a non-dedicated Novell server. We initially posed the two questions: (1) Is there a need for networked virtual reality? (2) In what ways can the technology be made available to the most people possible?

  16. Flight-Tested Prototype of BEAM Software

    Science.gov (United States)

    Mackey, Ryan; Tikidjian, Raffi; James, Mark; Wang, David

    2006-01-01

    Researchers at JPL have completed a software prototype of BEAM (Beacon-based Exception Analysis for Multi-missions) and successfully tested its operation in flight onboard a NASA research aircraft. BEAM (see NASA Tech Briefs, Vol. 26, No. 9; and Vol. 27, No. 3) is an ISHM (Integrated Systems Health Management) technology that automatically analyzes sensor data and classifies system behavior as either nominal or anomalous, and further characterizes anomalies according to strength, duration, and affected signals. BEAM (see figure) can be used to monitor a wide variety of physical systems and sensor types in real time. In this series of tests, BEAM monitored the engines of a Dryden Flight Research Center F-18 aircraft, and performed onboard, unattended analysis of 26 engine sensors from engine startup to shutdown. The BEAM algorithm can detect anomalies based solely on the sensor data, which includes but is not limited to sensor failure, performance degradation, incorrect operation such as unplanned engine shutdown or flameout in this example, and major system faults. BEAM was tested on an F-18 simulator, static engine tests, and 25 individual flights totaling approximately 60 hours of flight time. During these tests, BEAM successfully identified planned anomalies (in-flight shutdowns of one engine) as well as minor unplanned anomalies (e.g., transient oil- and fuel-pressure drops), with no false alarms or suspected false-negative results for the period tested. BEAM also detected previously unknown behavior in the F- 18 compressor section during several flights. This result, confirmed by direct analysis of the raw data, serves as a significant test of BEAM's capability.

  17. Prototype COBRA near-real-time processor

    Science.gov (United States)

    Earp, Samuel L.; Marshall, J. W.; Anthony, E. R.

    1996-05-01

    The U.S. Marine Corps COBRA countermine surveillance program has developed, as a risk- reduction alternative, a near real-time processor for the output of the COBRA multispectral camera. This processor has been tested using approximately 13.5 hours of video data from the COBRA DT-0 developmental test, representing approximately 243,000 frames of multispectral data. The results have been very encouraging--the system is robust and the minefield detection performance has met the goals of the COBRA program. The MITRE COBRA prototype processor is built from commercial-off-the-shelf VME bus technology. Video capture is provided by a Transtech TDM 435 capture/display VME card. Control is performed on a GMSV64 Super Sparc card that resides in two VME slots. The compute engine consists of two Pentek 4270 Quad TMS320C40 digital signal processing boards. There are two additional 6U VME boards to provide fast SCSI IO. The system is capable of capturing, digitizing and processing the COBRA data stream at between one-eighth and one-half real-time, depending on processing options. The nominal compute power of the system is 2.2 GOPS, 450 MFLOPS. The system is easily upgradeable due to the open architecture--one proposed upgrade will be to increase the number of available TMS320C40 processors to sixteen, providing real-time performance without compromising the current investment in software and hardware. The software for the system is primarily written in C, with hand-optimized assembler code for portions of the compute kernel. The algorithm that is implemented is based on the MITRE minefield detection algorithm detailed at AeroSense '95. The system development required a registration algorithm--this was the only algorithm development that was performed, the rest of the algorithms coming from previous MITRE effort on the COBRA program. Lessons learned from the development and upgrade/test plans will be presented.

  18. A Prototype for Passive Gamma Emission Tomography

    International Nuclear Information System (INIS)

    Combined efforts of multiple stakeholders of the IAEA Support Programme task JNT 1510: ''Prototype of passive gamma emission tomograph (PGET)'', resulted in the design, manufacturing and extensive testing of an advanced verification tool for partial defect testing on light water reactor spent fuel. The PGET has now reached a proven capability of detecting a single missing or substituted pin inside a BWR and VVER-440 fuel assemblies. The task started in 2004 and it is planned to be finished this year. The PGET head consists of two banks of 104 CdTe detectors each with integrated data acquisition electronics. The CdTe detectors are embedded in tungsten collimators which can be rotated around the fuel element using an integrated stepping motor mounted on a rotating table. All components are packed inside a toroid watertight enclosure. Control, data acquisition and image reconstruction analysis is fully computerized and automated. The design of the system is transportable and suitable for safeguards verifications in spent fuel ponds anywhere. Four test campaigns have been conducted. In 2009, the first test in Ringhals NPP failed collecting data but demonstrated suitability of the PGET for field deployments. Subsequent tests on fuel with increasing complexity were all successful (Ispra, Italy (2012), Olkiluoto, Finland (2013) and Loviisa, Finland (2014)). The paper will present the PGET design, results obtained from the test campaigns and mention also drawbacks that were experienced in the project. The paper also describes further tests which would allow evaluating the capabilities and limitations of the method and the algorithm used. Currently, the main technical shortcoming is long acquisition time, due to serial control and readout of detectors. With redesigned electronics it can be expected that the system would be able to verify a VVER-440 assembly in five minutes, which meets the IAEA user requirements. (author)

  19. Everything you need to know to operate on Day-Ahead{sup TM}; Tout ce que vous devez savoir pour intervenir sur Powernext Day-Ahead{sup TM}

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-05-15

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing the French power exchange through an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead{sup TM} since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures{sup TM} since 18 June 2004. This document is the user's guide of Powernext Day-Ahead{sup TM}. It presents: 1 - the power exchange in France (market model, Powernext's regulatory environment, general market operations, 2 - Powernext Day-Ahead{sup TM} members (membership, agreement, start-up notification, tariffs, standing obligations, membership termination), 3 - Powernext Day-Ahead{sup TM} products (specifications, management), 4 - trading (connections, system flow chart, ElWeb client installation and daily connections, portfolio-management, single bidding, type of order, submitting, importing, saving, sending, modifying or canceling an order form, transmission problems, block bidding block bid characteristics, sending, saving, transmitting, modifying and canceling a block bid, price calculations, blind auction procedure, example, taking into account block bids, rounding off rules, consulting and saving the results, sample documents, auction validation), 5 - clearing (LCH.Clearnet SA, legal framework, clearing agreement, PP-DPES agreement, market security, initial margin, daily adjustments, additional margin calls, trade-related financial flows, net financial position, value-added tax, settlement statements, general idea, characteristics and transmission method of settlement statements sample Documents, cash calls, settlement, default, sample cash call documents, financial Reports), 6 - delivery (balance responsible entity, file characteristics and transmission, imbalance settlement

  20. Reliability of the Woodway Curve(TM) Non-Motorized Treadmill for Assessing Anaerobic Performance.

    Science.gov (United States)

    Gonzalez, Adam M; Wells, Adam J; Hoffman, Jay R; Stout, Jeffrey R; Fragala, Maren S; Mangine, Gerald T; McCormack, William P; Townsend, Jeremy R; Jajtner, Adam R; Emerson, Nadia S; Robinson Iv, Edward H

    2013-01-01

    A curved treadmill offers a practical method of assessing anaerobic power by enabling unrestricted running motion and greater sport specificity. The purpose of this research was to determine reliability of a curved treadmill (cTM) sprint test and to compare performance measures to the traditional Wingate anaerobic power test (WAnT) performed on a cycle ergometer. Thirty-two recreationally active men and women (22.4 ± 2.8 yrs; 1.73 ± 0.08 m; 74. 2 ± 13.2 kg) performed four familiarization trials on cTM, followed by two randomly assigned experimental trials consisting of one 30-second maximum effort on either cTM or WAnT. Each trial was separated by at least 48 hours. Repeated measures analysis of variance (ANOVA), interclass correlations (ICC), standard error of measurement (SEM), and minimal differences (MD) were used to determine reliability of familiarization trials on cTM, and Pearson product moment correlations were calculated to compare cTM and WAnT. ANOVA results showed significant differences (p sprint test for recreationally active men and women. In addition, there are strong relationships between cTM and WAnT in assessing anaerobic performance. Key pointsThe Woodway Curve 3.0(TM) is a non-motorized treadmill utilizing a curved platform which allows individuals to simulate an unrestricted sprint test in a laboratory setting, offering a practical and sport specific method of assessing anaerobic power.The curved treadmill provides a reliable sprint test for recreationally active men and women.There are strong relationships between the curved treadmill and cycle ergometer in assessing anaerobic performance.

  1. Crystal growth and characterization of Tm doped mixed rare-earth aluminum perovskite

    Energy Technology Data Exchange (ETDEWEB)

    Totsuka, Daisuke, E-mail: totsuka@imr.tohoku.ac.jp [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Nihon Kessho Kogaku Co., Ltd., 810-5 Nobe-cho, Tatebayashi, Gunma 374-0047 (Japan); Yanagida, Takayuki [New Industry Creation Hatchery Center (NICHe), 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Sugiyama, Makoto; Fujimoto, Yutaka; Yokota, Yuui [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Yoshikawa, Akira [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); New Industry Creation Hatchery Center (NICHe), 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan)

    2012-04-15

    Highlights: Black-Right-Pointing-Pointer (Lu{sub x}Gd{sub y}Y{sub 0.99-x-y}Tm{sub 0.01})AP single crystals were grown by the {mu}-PD method. Black-Right-Pointing-Pointer The grown crystals were single phase with perovskite structure (Pbnm). Significant segregation of Lu and Gd was detected in the growth direction. Black-Right-Pointing-Pointer Some absorption bands due to Tm{sup 3+}, Gd{sup 3+} and color centers were exhibited. Black-Right-Pointing-Pointer Radioluminescence spectra showed several emission peaks ascribed to Tm{sup 3+} and Gd{sup 3+}. -- Abstract: In this work, we present results of structural characterization and optical properties including radio luminescence of (Lu{sub x}Gd{sub y}Y{sub 0.99-x-y}Tm{sub 0.01})AP single crystal scintillators for (x, y) = (0.30, 0.19), (0, 0.19) and (0, 0) grown by the micro-pulling-down ({mu}-PD) method. The grown crystals were single phase materials with perovskite structure (Pbnm) as confirmed by XRD and had a good crystallinity. The distribution of the crystal constituents in growth direction was evaluated, and significant segregation of Lu and Gd was detected in (Lu{sub 0.30}Gd{sub 0.19}Y{sub 0.50}Tm{sub 0.01})AP sample. The crystals demonstrated 70% transmittance in visible wavelength range and some absorption bands due to Tm{sup 3+}, Gd{sup 3+} and color centers were exhibited in 190-900 nm. The radioluminescence measurement under X-ray irradiation demonstrated several emission peaks ascribed to 4f-4f transitions of Tm{sup 3+} and Gd{sup 3+}. The ratio of emission intensity in longer wavelength range was increased when Y was replaced by Lu or Gd.

  2. Influence of radiation on endotoxin test using the PTS TM for 18-FDG radiopharmaceutical

    Directory of Open Access Journals (Sweden)

    Ralph Santos-Oliveira

    2010-09-01

    Full Text Available F-18 FDG (2-[18-F] fluoro-2-deoxy-D-glucose is the most frequently used radiopharmaceutical for PET and PET CT imaging exams. The FDA recently approved the use of the PTS TM (Portable Test System as an alternative to the standard test proposed by the United States Pharmacopeia using the LAL (Limulus Amebocyte Lysates, that takes longer to perform (about 1h than the PTS TM (15 min. Recent studies have demonstrated that radiation could interfere with the PTS TM test. In order to study the effects of radiation on the PTS TM test and/or equipment, 27 batches of F-18 FDG produced in the Nuclear Engineering Institute were analyzed. The results showed that no direct correlation with radiation was found in any of the cases.O FDG-18 é o radiofármaco mais utilizado nos exames de PET e PET CT. O FDA recentemente aprovou o uso do PTS TM (Portable Test System como método alternativo ao teste padrão de endotoxina, proposto pela Farmacopéia Americana, considerando que no primeiro há um tempo de espera de 1 hora frente a somente 15 minutos do segundo. Estudo recentes demonstram que a radiação poderia interferir no teste do PTS TM. De modo a avaliar os efeitos da radiação no teste PTS TM foram analisados 27 lotes de F-18 FDG produzidos no Instituto de Engenharia Nuclear. Os resultados demonstraram que em todos os casos nenhuma correlação direta com a radiação foi observada.

  3. Realization of modulating broadband emission from Er–Tm codoped calcium boroaluminate glasses by dual-wavelength pumping

    International Nuclear Information System (INIS)

    Near-infrared photoluminescence (PL) of calcium boroaluminate (CABAL) glasses codoped with Er2O3 and Tm2O3 has been investigated by dual-wavelength pumping at 795 and 476 nm. Spectrum shape of broadband emission could be modulated by controlling the power ratio of two pumping lines (P476/P795). The result shows that the full width at half maximum can reach ∼500 nm in the wavelength range from 1.3 to 2.0 μm by controlling P476/P795 = 12. The PL spectra show four characteristic peaks located at 1.46, 1.53, 1.58 and 1.80 μm, corresponding to Tm3+: 3H4 → 3F4, Er3+: 4I13/2 → 4I15/2, Tm3+: 1G4 → 3F2 and Tm3+: 3F4 → 3H6 emissions, respectively. The energy transfer (ET) (ET1: Er3+: 4I13/2, Tm3+: 3F4 → Er3+: 4I15/2, Tm3+: 3H4 and ET2: Er3+: 4I13/2, Tm3+: 3H6 → Er3+: 4I15/2, Tm3+: 3F4) between Er3+ and Tm3+ ions play important roles in the luminescence mechanisms. In addition, a new ET process (ET: Tm3+: 1G4, Er3+: 4F9/2 → Tm3+: 3F2, Er3+: 4F7/2) was identified. The flat broadband emission with the bandwidth of ∼500 nm could be realized by changing P476/P795 as a result of the radiative transitions, Tm–Tm cross-relaxation (Tm3+: 3H4, 3H6 → Tm3+: 3F4, 3F4) and Er–Tm ET processes. -- Highlights: ► Dual-wavelength pumping has been applied to modulate broadband emission in rare-earth-doped materials. ► It is easier to control the pumping source than the concentration of sample for modulating broadband emission. ► The broadband and flat emission with the bandwidth of ∼500 nm has been realized through dual-wavelength. ► This would be caused by the radiative transitions, Tm–Tm cross-relaxation and Er–Tm energy transfer processes.

  4. Identifying prototypical components in behaviour using clustering algorithms.

    Directory of Open Access Journals (Sweden)

    Elke Braun

    Full Text Available Quantitative analysis of animal behaviour is a requirement to understand the task solving strategies of animals and the underlying control mechanisms. The identification of repeatedly occurring behavioural components is thereby a key element of a structured quantitative description. However, the complexity of most behaviours makes the identification of such behavioural components a challenging problem. We propose an automatic and objective approach for determining and evaluating prototypical behavioural components. Behavioural prototypes are identified using clustering algorithms and finally evaluated with respect to their ability to represent the whole behavioural data set. The prototypes allow for a meaningful segmentation of behavioural sequences. We applied our clustering approach to identify prototypical movements of the head of blowflies during cruising flight. The results confirm the previously established saccadic gaze strategy by the set of prototypes being divided into either predominantly translational or rotational movements, respectively. The prototypes reveal additional details about the saccadic and intersaccadic flight sections that could not be unravelled so far. Successful application of the proposed approach to behavioural data shows its ability to automatically identify prototypical behavioural components within a large and noisy database and to evaluate these with respect to their quality and stability. Hence, this approach might be applied to a broad range of behavioural and neural data obtained from different animals and in different contexts.

  5. Neural basis of scientific innovation induced by heuristic prototype.

    Directory of Open Access Journals (Sweden)

    Junlong Luo

    Full Text Available A number of major inventions in history have been based on bionic imitation. Heuristics, by applying biological systems to the creation of artificial devices and machines, might be one of the most critical processes in scientific innovation. In particular, prototype heuristics propositions that innovation may engage automatic activation of a prototype such as a biological system to form novel associations between a prototype's function and problem-solving. We speculated that the cortical dissociation between the automatic activation and forming novel associations in innovation is critical point to heuristic creativity. In the present study, novel and old scientific innovations (NSI and OSI were selected as experimental materials in using learning-testing paradigm to explore the neural basis of scientific innovation induced by heuristic prototype. College students were required to resolve NSI problems (to which they did not know the answers and OSI problems (to which they knew the answers. From two fMRI experiments, our results showed that the subjects could resolve NSI when provided with heuristic prototypes. In Experiment 1, it was found that the lingual gyrus (LG; BA18 might be related to prototype heuristics in college students resolving NSI after learning a relative prototype. In Experiment 2, the LG (BA18 and precuneus (BA31 were significantly activated for NSI compared to OSI when college students learned all prototypes one day before the test. In addition, the mean beta-values of these brain regions of NSI were all correlated with the behavior accuracy of NSI. As our hypothesis indicated, the findings suggested that the LG might be involved in forming novel associations using heuristic information, while the precuneus might be involved in the automatic activation of heuristic prototype during scientific innovation.

  6. Visible to near-infrared down-shifting in Tm3+ doped fluoride glasses for solar cells efficiency enhancement

    Science.gov (United States)

    Maalej, Olfa; Merigeon, Julien; Boulard, Brigitte; Girtan, Mihaela

    2016-10-01

    In this paper, down-conversion of Tm3+ doped fluoride ZLAG glasses with composition of 70.2ZrF4-(23.4-x)LaF3-0.6AlF3-5.8GaF3-xTmF3 (x = 0.25, 0.5, 0.75, 1, 2, 3 and 5 mol%) were tested as encapsulation materials for solar cells. The current density - voltage (J-V) characterizations were performed under solar simulator irradiation. The influence of Tm3+ concentration on the mono crystalline silicon solar cells performances was investigated. A slight increase of the solar cell efficiency was observed in the case of fluoride ZLAG for Tm3+ doping concentrations up to 1 mol% Tm3+. Further increase of the Tm3+ concentration leads to a decrease of solar cell conversion efficiency as a result of concentration quenching.

  7. System Test of a Prototype LHCb RICH Detector

    CERN Document Server

    Patel, M

    2004-01-01

    A prototype of the LHCb Ring Imaging Cherenkov detector has been constructed. The prototype module contained a pre-production Pixel Hybrid Photon Detector, mounted on the final photon detector mechanics. The photon detector was read out at the full LHC speed of 40 MHz using the full prototype on-detector RICH electronics readout chain. The readout uses radiation-tolerant FPGA technology, 1.6 GHz optical links and 40 MHz trigger-timing and control (TTC). The photon detector was mounted in a gas vessel and Cherenkov rings have been observed from and N$_2$ radiator using electron and pion beams.

  8. Rapid Prototyping with Fourth Generation Systems - an Empirical Study

    DEFF Research Database (Denmark)

    Grønbæk, Kaj

    1989-01-01

    Discusses experiences on the development and use of horizontal and vertical prototypes. Explains the difference. Resolves that horizontal prototypes can be developed with 'little effort', but end users are reluctant to become involved in the development process. Contrastingly resolves that vertical...... prototypes appear to stimulate constructive response. Reasons that developers should be aware of the tacit knowledge which plays an important part in users' work practices and should be involved early in the development process. Proposes three techniques to meet the requirements – participation, simulation...

  9. Does Regional Difference Account for the Formation of Prototype?

    Institute of Scientific and Technical Information of China (English)

    王陆

    2001-01-01

    The study of categorization and prototype has been an interesting subject for the scholars in psycholinguistics. They have done different studies to investigate the reasons for the formation of the prototype in people's mind. Some scholars believe that cultural factors play an important role in the formation of prototype. This paper is intended to look into the categorization of the fruits in China, and the researcher hopes to get the factors which may to some extent influence their idea of typicality. The researcher believes that the regions where a person grows up in may have a subtle effect on his or her idea of typicality of certain items.

  10. A prototype of workflow management system for construction design projects

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    A great deal of benefits can be achieved if information and process are integrated within the building design project. This paper aims to establish a prototype of workflow management system for construction design project through the application of workflow technology. The composition and function of prototype is presented to satisfy the needs of information share and process integration. By integrating all subsystems and modules of the prototype, the whole system can deal with design information-flow modeling, emulating and optimizing, task planning and distributing, automatic tracking and monitoring, as well as network service, etc. In this way, the collaborative design environment of building design project is brought into being.

  11. Flexible surveillance system architecture for prototyping video content analysis algorithms

    Science.gov (United States)

    Wijnhoven, R. G. J.; Jaspers, E. G. T.; de With, P. H. N.

    2006-01-01

    Many proposed video content analysis algorithms for surveillance applications are very computationally intensive, which limits the integration in a total system, running on one processing unit (e.g. PC). To build flexible prototyping systems of low cost, a distributed system with scalable processing power is therefore required. This paper discusses requirements for surveillance systems, considering two example applications. From these requirements, specifications for a prototyping architecture are derived. An implementation of the proposed architecture is presented, enabling mapping of multiple software modules onto a number of processing units (PCs). The architecture enables fast prototyping of new algorithms for complex surveillance applications without considering resource constraints.

  12. NEON Citizen Science: Planning and Prototyping

    Science.gov (United States)

    Newman, S. J.; Henderson, S.; Gardiner, L. S.; Ward, D.; Gram, W.

    2011-12-01

    chosen as the focus of this citizen science campaign because it is a visible and comprehensible way of demonstrating the effects of climate change. In addition, plants are readily accessible in nearly every neighborhood and park, and wild area across the continent, so people can make observations whether they live near an inner city park or in the rural countryside. Recently, NEON developed data visualization tools for Project BudBurst to engage citizen science participants in "doing science" beyond data collection. By prototyping NEON citizen science through Project BudBurst, NEON is developing a better understanding of how to build a citizen science program that addresses areas of awareness, mastery, and leadership of scientific information like that which NEON will produce over the next 30 years.

  13. NEON Citizen Science: Planning and Prototyping (Invited)

    Science.gov (United States)

    Gram, W.

    2010-12-01

    . Phenology was chosen as the focus of this citizen science campaign because it is a visible and comprehensible way of demonstrating the effects of climate change. In addition, plants are readily accessible in nearly every neighborhood and park, and wild areas across the continent, so people can make observations whether they live near an inner city park or in the rural countryside. Recently, NEON built 3 web tools that enable users to visualize PBB data. The tools include a mapping function that displays selected PBB distributional data on a map, an animated map that shows “green up” through time and space, and a graphing tool that compares number of species flowering or leafing out with day length. This prototyping will help NEON better understand how to engage citizen science participants in “doing science” beyond data collection.

  14. Up-conversion emission in KGd(WO 4 ) 2 single crystals triply-doped with Er 3+ /Yb 3+ /Tm 3+ , Tb 3+ /Yb 3+ /Tm 3+ and Pr 3+ /Yb 3+ /Tm 3+ ions

    Science.gov (United States)

    Kasprowicz, D.; Brik, M. G.; Majchrowski, A.; Michalski, E.; Głuchowski, P.

    2011-09-01

    Triply-doped single crystals KGd(WO 4) 2:Er 3+/Yb 3+/Tm 3+, KGd(WO 4) 2:Tb 3+/Yb 3+/Tm 3+ and KGd(WO 4) 2:Pr 3+/Yb 3+/Tm 3+ were grown by the Top Seeded Solution Growth (TSSG) method, with an aim of getting efficient up-converted multicolored luminescence, which subsequently can be used for generation of white light. Such an aim determined the choice of the triply doped compounds: excitation of the Yb 3+ ions in the infrared spectral region is followed by red, green and blue emission from other dopants. It was shown that all these systems exhibit multicolor up-conversion fluorescence under 980 nm laser irradiation. Detailed spectroscopic studies of their absorption and luminescence spectra were performed. From the analysis of the dependence of the intensity of fluorescence on the excitation power the conclusion was made about significant role played by the host's conduction band and other possible defects of the KGd(WO 4) 2 crystal lattice in the up-conversion processes.

  15. Evaluation of the boundary layer dynamics of the TM5 model over Europe

    Science.gov (United States)

    Koffi, E. N.; Bergamaschi, P.; Karstens, U.; Krol, M.; Segers, A.; Schmidt, M.; Levin, I.; Vermeulen, A. T.; Fisher, R. E.; Kazan, V.; Klein Baltink, H.; Lowry, D.; Manca, G.; Meijer, H. A. J.; Moncrieff, J.; Pal, S.; Ramonet, M.; Scheeren, H. A.; Williams, A. G.

    2016-09-01

    We evaluate the capability of the global atmospheric transport model TM5 to simulate the boundary layer dynamics and associated variability of trace gases close to the surface, using radon (222Rn). Focusing on the European scale, we compare the boundary layer height (BLH) in the TM5 model with observations from the National Oceanic and Atmospheric Admnistration (NOAA) Integrated Global Radiosonde Archive (IGRA) and also with ceilometer and lidar (light detection and ranging) BLH retrievals at two stations. Furthermore, we compare TM5 simulations of 222Rn activity concentrations, using a novel, process-based 222Rn flux map over Europe (Karstens et al., 2015), with harmonised 222Rn measurements at 10 stations. The TM5 model reproduces relatively well the daytime BLH (within 10-20 % for most of the stations), except for coastal sites, for which differences are usually larger due to model representation errors. During night, however, TM5 overestimates the shallow nocturnal BLHs, especially for the very low observed BLHs (concentration simulations based on the new 222Rn flux map show significant improvements especially regarding the average seasonal variability, compared to simulations using constant 222Rn fluxes. Nevertheless, the (relative) differences between simulated and observed daytime minimum 222Rn activity concentrations are larger for several stations (on the order of 50 %) than the (relative) differences between simulated and observed BLH at noon. Although the nocturnal BLH is often higher in the model than observed, simulated 222Rn nighttime maxima are actually larger at several continental stations. This counterintuitive behaviour points to potential deficiencies of TM5 to correctly simulate the vertical gradients within the nocturnal boundary layer, limitations of the 222Rn flux map, or issues related to the definition of the nocturnal BLH. At several stations the simulated decrease of 222Rn activity concentrations in the morning is faster than observed

  16. Spectroscopic and lasing properties of calcium niobium gallium garnet activated with Tm(3+) and Cr(3+) ions

    Energy Technology Data Exchange (ETDEWEB)

    Voron' ko, IU.K.; Gessen, S.B.; Es' kov, N.A.; Zverev, A.A.; Riabochkina, P.A.; Sobol' , A.A.; Ushakov, S.N.; Tsymbal, L.I. (Inst. Obshchei Fiziki, Moscow (Russian Federation))

    1992-07-01

    Spectroscopic and lasing properties of a calcium-niobium-gallium-garnet (CNGG) Tm:Cr crystal were investigated focusing on the kinetics of luminescence decay of the Cr(3+) ions. An efficient nonradiative energy transfer from the Cr(3+) to Tm(3+) ions was observed at room temperature. Free-running lasing of CNGG:Tm:Cr crystals occurred at a wavelength of 2.02 microns. 10 refs.

  17. Numerical simulation during vacuum sublimation purification of metal Tm (Ⅰ): model foundation and validation

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xiaowei; MIAO Ruiying; CHEN Dehong; WANG Zhiqiang; LI Zongan; YAN Shihong; JIN Xiaoli

    2013-01-01

    The thermo physical parameters of Tm vapor and the range of sublimation temperature were determined by vapor pressure of metal Tm,and a 2-D axis-symmetric heat transfer model was developed to investigate the temperature distribution in sublimation furnace.The simulation results showed that,due to the heat loss at crucible bottom,the temperature of crucible,solid metal and Tm vapor increased with crucible height increasing,reached the maximum value in the middle of crucible in height direction,and then decreased rapidly; at the outside surface of condenser,the temperature decreased sharply; with heating body temperature of 1000 ℃,the mean temperature at upper surface of solid Tm was 22 ℃ higher than that on the lower surface,the mean temperature of upper surface of solid Tm was about 32 ℃ lower than that of heating body,and the calculated sublimation velocity was 8.16 g/cm2/h,which was only 54.4% of sublimation velocity calculation by heating body temperature.

  18. Detection of soil erosion within pinyon-juniper woodlands using Thematic Mapper (TM) data

    Science.gov (United States)

    Price, Kevin P.

    1993-01-01

    Multispectral measurements collected by Landsat Thematic Mapper (TM) were correlated with field measurements, direct soil loss estimates, and Universal Soil Loss Equation (USLE) estimates to determine the sensitivity of TM data to varying degrees of soil erosion in pinyon-juniper woodland in central Utah. TM data were also evaluated as a predictor of the USLE Crop Management C factor for pinyon-juniper woodlands. TM spectral data were consistently better predictors of soil erosion factors than any combination of field factors. TM data were more sensitive to vegetation variations than the USLE C factor. USLE estimates showed low annual rates of erosion which varied little among the study sites. Direct measurements of rate of soil loss using the SEDIMENT (Soil Erosion DIrect measureMENT) technique, indicated high and varying rates of soil loss among the sites since tree establishment. Erosion estimates from the USLE and SEDIMENT methods suggest that erosion rates have been severe in the past, but because significant amounts of soil have already been eroded, and the surface is now armored by rock debris, present erosion rates are lower. Indicators of accelerated erosion were still present on all sites, however, suggesting that the USLE underestimated erosion within the study area.

  19. Preparation and luminescence properties of BaWO4:Yb3+/Tm3+nano-crystal

    Institute of Scientific and Technical Information of China (English)

    贺超; 杨魁胜; 刘磊; 司振君

    2013-01-01

    This research investigated the effect of different contents of Tm3+and different concentration ratios of Yb/Tm on the lumi-nescent properties of BaWO4:Yb3+/Tm3+nano-crystal synthesized by the hydrothermal method. The results indicated that lumines-cence intensity reached the strongest when CTm=1.0 mol.% and CYb/CTm=2:1. X-ray diffraction revealed the tetragonal system of BaWO4:Yb3+/Tm3+and the grain sizes were between 31 and 45 nm according to Scherrer equation. The results of X-ray diffraction and scanning electron microscopy were similar. Four emission peaks at 454, 475, 647 and 790 nm including two blue emission peaks and two red emission peaks, corresponding to 1D2→3F4 , 1G4→3H6, 1G4→3F4 and 3H4→3H6 transitions of Tm3+, were observed under excitation of 980 nm semiconductor laser. Blue emissions at 454 and 475 nm were four-photon and three-photon absorption respec-tively in accordance with the relationship between luminescence intensity and pump power.

  20. RadBall{sup TM} Technology Testing and MCNP Modeling of the Tungsten Collimator

    Energy Technology Data Exchange (ETDEWEB)

    Farfan, Eduardo B; Foley, Trevor Q; Coleman, J Rusty; Jannik, G Timothy; Holmes, Christopher J; Oldham, Mark; Adamovics, John; Stanley, Steven J, E-mail: Eduardo.Farfan@srnl.doe.go

    2010-11-01

    The UK's National Nuclear Laboratory (NNL) has developed a remote, non-electrical, radiation-mapping device known as RadBall{sup TM}, which can locate and quantify radioactive hazards within contaminated areas of the nuclear industry. RadBall{sup TM} consists of a colander-like outer shell that houses a radiation-sensitive polymer sphere. The outer shell works to collimate radiation sources and those areas of the polymer sphere that are exposed react, becoming increasingly more opaque, in proportion to the absorbed dose. The polymer sphere is imaged in an optical-CT scanner, which produces a high resolution 3D map of optical attenuation coefficients. Subsequent analysis of the optical attenuation matrix provides information on the spatial distribution of sources in a given area forming a 3D characterization of the area of interest. RadBall{sup TM} has no power requirements and can be positioned in tight or hard-to reach locations. The RadBall{sup TM} technology has been deployed in a number of technology trials in nuclear waste reprocessing plants at Sellafield in the UK and facilities of the Savannah River National Laboratory (SRNL). This study focuses on the RadBall{sup TM} testing and modeling accomplished at SRNL.

  1. Evaluation of Petrifilms(TM) as a diagnostic test to detect bovine mastitis organisms in Kenya.

    Science.gov (United States)

    Gitau, George K; Bundi, Royford M; Vanleeuwen, John; Mulei, Charles M

    2013-03-01

    The study purpose was to validate Petrifilms(TM) (3M Microbiology, 2005) against standard culture methods in the diagnosis of bovine mastitis organisms in Kenya. On 128 smallholder dairy cattle farms in Kenya, between June 21, 2010 and August 31, 2010, milk samples from 269 cows that were positive on California Mastitis Test (CMT) were cultured using standard laboratory culture methods and Petrifilms(TM) (Aerobic Count and Coliform Count -3M Microbiology, 2005), and results were compared. Staphylococcus aureus was the most common bacterium isolated (73 % of samples). Clinical mastitis was found in only three cows, and there were only two Gram-negative isolates, making it impossible to examine the agreement between the two tests for Gram-negative- or clinical mastitis samples. The observed agreement between the standard culture and Petrifilm(TM) (3M Microbiology, 2005) results for Gram-positive isolates was 85 %, and there was fair agreement beyond that expected due to chance alone, with a kappa (κ) of 0.38. Using culture results as a gold standard, the Petrifilms(TM) had a sensitivity of 90 % for Gram-positive samples and specificity of 51 %. With 87 % of CMT-positive samples resulting in Gram-positive pathogens cultured, there was a positive predictive value of 93 % and a negative predictive value of 43 %. Petrifilms(TM) should be considered for culture of mastitis organisms in developing countries, especially when Gram-positive bacteria are expected. PMID:23108587

  2. [Mid-infrared emission and multiphonon relaxation in Tm3+-doped Ge-Ga-Se glasses].

    Science.gov (United States)

    Zhang, Peng-Jun; Dai, Shi-Xun; Le, Fang-Da; Peng, Bo; Xu, Tie-Feng; Nie, Qiu-Hua; Zhang, Xiang-Hua

    2010-06-01

    A series of chalcogenide glasses based on the composition Ge30 Ga5 Se65 (at. %) doped with the different Tm3+ ions were synthesized by melt-quenching technique. The refractive indexes, Raman spectra, absorption spectra, near-and mid-infrared fluorescence, and lifetimes of glass samples under 800 nm laser excitation were measured. The intensity parameters omega(i) (i = 2, 4, 6), transition probabilities, branching ratios and radiative lifetimes have been predicted for Tm3+ ions in samples by using the Judd-Ofelt theory. The near-infrared emission spectra at 1.23, 1.48 and 1.8 microm were observed and their quantum efficiencies were evaluated respectively in glass doped with 1 Wt% Tm(3+)-ions under 800 nm excitation. The mid-infrared fluorescence spectra were investigated with the different Tm3+ ion concentration under 800 nm excitation. The multiphonon relaxation rate of Tm3+ : 3 H5 --> 3F4 by the measured and calculated lifetimes, and the relative parameters of W(0) and a in Ge30 Ga5 Se65 glass were evaluated. Results show that the multiphonon relaxation rates were significantly lower than other glasses due to the lower maximum phonon energy, so the selenide glasses are promising as host materials for doping by rare earth ions and for preparation of mid-infrared optical elements. PMID:20707130

  3. Prototype Weigh-In-Motion Performance

    Energy Technology Data Exchange (ETDEWEB)

    Abercrombie, Robert K [ORNL; Beshears, David L [ORNL; Hively, Lee M [ORNL; Scudiere, Matthew B [ORNL; Sheldon, Frederick T [ORNL

    2006-10-01

    Oak Ridge National Laboratory (ORNL) has developed and patented methods to weigh slowly moving vehicles. We have used this technology to produce a portable weigh-in-motion system that is robust and accurate. This report documents the performance of the second-generation portable weigh-in-motion prototype (WIM Gen II). The results of three modes of weight determination are compared in this report: WIM Gen II dynamic mode, WIM Gen II stop-and-go mode, and static (parked) mode on in-ground, static scales. The WIM dynamic mode measures axle weights as the vehicle passes over the system at speeds of 3 to 7 miles per hour (1.3 to 3.1 meters/second). The WIM stop-and-go mode measures the weight of each axle of the vehicle as the axles are successively positioned on a side-by-side pair of WIM measurement pads. In both measurement modes the center of balance (CB) and the total weight are obtained by a straight-forward calculation from axle weights and axle spacings. The performance metric is measurement error (in percent), which is defined as 100 x (sample standard deviation)/(average); see Appendix A for details. We have insufficient data to show that this metric is predictive. This report details the results of weight measurements performed in May 2005 at two sites using different types of vehicles at each site. In addition to the weight measurements, the testing enabled refinements to the test methodology and facilitated an assessment of the influence of vehicle speed on the dynamic-mode measurements. The initial test at the National Transportation Research Center in Knoxville, TN, involved measurements of passenger and light-duty commercial vehicles. A subsequent test at the Arrival/Departure Airfield Control Group (A/DACG) facility in Ft. Bragg, NC, involved military vehicles with gross weights between 3,000 and 75,000 pounds (1,356 to 33,900 kilograms) with a 20,000-pound (9,040 kilograms) limit per axle. For each vehicle, four or more separate measurements were done

  4. Highly Tm3+ doped germanate glass and its single mode fiber for 2.0 μm laser

    OpenAIRE

    Xin Wen; Guowu Tang; Qi Yang; Xiaodong Chen; Qi Qian; Qinyuan Zhang; Zhongmin Yang

    2016-01-01

    Highly Tm3+ doped optical fibers are urgently desirable for 2.0 μm compact single-frequency fiber laser and high-repetition-rate mode-locked fiber laser. Here, we systematically investigated the optical parameters, energy transfer processes and thermal properties of Tm3+ doped barium gallo-germanate (BGG) glasses. Highly Tm3+ doped BGG glass single mode (SM) fibers were fabricated by the rod-in-tube technique. The Tm3+ doping concentration reaches 7.6 × 1020 ions/cm3, being the reported highe...

  5. Study on differences between high contrast grating reflectors for TM and TE polarizations and their impact on VCSEL designs

    DEFF Research Database (Denmark)

    Chung, Il-Sug

    2015-01-01

    A theoretical study of differences in broadband high-indexcontrast grating (HCG) reflectors for TM and TE polarizations is presented, covering various grating parameters and properties of HCGs. It is shown that the HCG reflectors for TM polarization (TM HCG reflectors) have much thicker grating...... thicknesses and smaller grating periods than the TE HCG reflectors. This difference is found to originate from the different boundary conditions met for the electric field of each polarization. Due to this difference, the TM HCG reflectors have much shorter evanescent extension of HCG modes into low...

  6. The SEOM Sentinel-3 Hydrologic Altimetry Processor prototypE project

    Science.gov (United States)

    Fabry, Pierre; Benveniste, Jérôme; Fernandes, Joana; Roca, Mònica; Ambrózio, Américo; Restano, Marco; Bercher, Nicolas; Gustafsson, David

    2016-07-01

    This communication deals with the SHAPE study that was kicked off on 14 September 2015. SHAPE stands for Sentinel-3 Hydrologic Altimetry Processor prototypE. The team, the objectives, the work breakdown structure, the methodology, the technical approaches, the first results as well as the status and the upcoming milestones of the project will be presented. This study is part of SEOM, Scientific Exploitation of Operational Missions, an ESA programme element which aims at expanding the international research community, strengthening the leadership of the European EO research community and addressing new scientific researches. This Research and Development study not only intends to make the best use of all recent improvements in altimetry but also clearly pushes for major breakthroughs that should boost the scientific use of the SAR altimetry data in hydrology. The stakes are high in the context of climate change, as scientists need to improve their analyses of water stocks and exchanges over wide geographical regions. The study focuses on three main variables of interest in hydrology: river stage, river discharge and lake level, which are part of the Terrestrial Essential Climate Variables (TECV) defined by GCOS. It also is the scientific step towards a future Inland Water dedicated processor on the Sentinel-3 ground segment. The main characteristics of the project will be summarized. Cooperation with the scientific community will be encouraged. Project documents available at the website (ATBD for example) will go through a critical review outside the project team so as to collect feedback. Valuable feedback will be taken into account so as to provide a new processing chain prototype that should be capable of providing high quality water heights, making it possible to couple it with the hydrological dynamic and semi-distributed model HYPE (Hydrological Predictions for the Environment). This model has been developed by SMHI and will be used to assimilate study's new

  7. The SEOM Sentinel-3 Hydrologic Altimetry Processor prototypE (SHAPE) Project

    Science.gov (United States)

    Fabry, Pierre; Bercher, Nicolas; Roca, Mònica; Martinez, Bernat; Nilo, Pablo; Ray, Chris; Moyano, Gorka; Fernandes, Joana; Lázaro, Clara; Gustafsson, David; Arheimer, Berit; Ambrózio, Américo; Restano, Marco; Benveniste, Jérôme

    2016-04-01

    The SHAPE study was kicked off in September 2015. SHAPE stands for Sentinel-3 Hydrologic Altimetry Processor prototypE. The team, the objectives, the work breakdown structure, the methodology, the technical approaches, the first results as well as the status and the upcoming milestones of the project will be presented. This study is part of SEOM, Scientific Exploitation of Operational Missions, an ESA programme element which aims at expanding the international research community, strengthening the leadership of the European EO research community and addressing new scientific researches. This Research and Development study not only intends to make the best use of all recent improvements in altimetry but also clearly pushes for major breakthroughs that should boost the scientific use of the SAR altimetry data in hydrology. The stakes are high in the context of climate change, as scientists need to improve their analyses of water stocks and exchanges over wide geographical regions. The study focuses on three main variables of interest in hydrology: river stage, river discharge and lake level, which are part of the Terrestrial Essential Climate Variables (TECV) defined by GCOS. It also is the scientific step towards a future Inland Water dedicated processor on the Sentinel-3 ground segment. The main characteristics of the project will be summarized. Cooperation with the scientific community will be encouraged. Project documents available at the website (ATBD for example) will go through a critical review outside the project team so as to collect feedback. Valuable feedback will be taken into account so as to provide a new processing chain prototype that should be capable of providing high quality water heights, making it possible to couple it with the hydrological dynamic and semi-distributed model HYPE (Hydrological Predictions for the Environment). This model has been developed by SMHI and will be used to assimilate study's new "Alti-Hydro" Products to assess the

  8. Prototype-Technology Evaluator and Research Aircraft Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Area-I team has developed and flight tested the unmanned Prototype-Technology Evaluation and Research Aircraft or PTERA ("ptera" being Greek for wing, or...

  9. Prototype Spallation Neutron Source Rotating Target Assembly Final Test Report

    Energy Technology Data Exchange (ETDEWEB)

    McManamy, Thomas J [ORNL; Graves, Van [Oak Ridge National Laboratory (ORNL); Garmendia, Amaia Zarraoa [IDOM Bilbao; Sorda, Fernando [ESS Bilbao; Etxeita, Borja [IDOM Bilbao; Rennich, Mark J [ORNL

    2011-01-01

    A full-scale prototype of an extended vertical shaft, rotating target assembly based on a conceptual target design for a 1 to 3-MW spallation facility was built and tested. Key elements of the drive/coupling assembly implemented in the prototype include high integrity dynamic face seals, commercially available bearings, realistic manufacturing tolerances, effective monitoring and controls, and fail-safe shutdown features. A representative target disk suspended on a 3.5 meter prototypical shaft was coupled with the drive to complete the mechanical tests. Successful operation for 5400 hours confirmed the overall mechanical feasibility of the extended vertical shaft rotating target concept. The prototype system showed no indications of performance deterioration and the equipment did not require maintenance or relubrication.

  10. Prototype solar heating and combined heating cooling systems

    Science.gov (United States)

    1978-01-01

    The design and development of eight prototype solar heating and combined heating and cooling systems is discussed. The program management and systems engineering are reported, and operational test sites are identified.

  11. Customization of gaming technology and prototyping of rehabilitation applications

    DEFF Research Database (Denmark)

    Herbelin, Bruno; Ciger, Jan; Lewis Brooks, Anthony

    2008-01-01

    The field of rehabilitation has recently seen various experimentations with games using interfaces that require physical activity. In order to establish the basis for developments and experimentations with those interactive systems, we propose a rapid prototyping approach using various commercial...

  12. Zion Augmented Reality Application (ZARA): An Augmented Heritage Prototype

    OpenAIRE

    Odland, Johannes Johannesen

    2007-01-01

    This paper describes the investigation and development of a virtual heritage application that employs augmented reality to disseminate a model of the Zion castle. The developed system is a flexible prototype that leverages several open source frameworks and applications.

  13. Solid modeling and applications rapid prototyping, CAD and CAE theory

    CERN Document Server

    Um, Dugan

    2016-01-01

    The lessons in this fundamental text equip students with the theory of Computer Assisted Design (CAD), Computer Assisted Engineering (CAE), the essentials of Rapid Prototyping, as well as practical skills needed to apply this understanding in real world design and manufacturing settings. The book includes three main areas: CAD, CAE, and Rapid Prototyping, each enriched with numerous examples and exercises. In the CAD section, Professor Um outlines the basic concept of geometric modeling, Hermite and Bezier Spline curves theory, and 3-dimensional surface theories as well as rendering theory. The CAE section explores mesh generation theory, matrix notion for FEM, the stiffness method, and truss Equations. And in Rapid Prototyping, the author illustrates stereo lithographic theory and introduces popular modern RP technologies. Solid Modeling and Applications: Rapid Prototyping, CAD and CAE Theory is ideal for university students in various engineering disciplines as well as design engineers involved in product...

  14. INITIATIVE RECOVER TRANSITIONAL DISASTER RECOVERY HOUSING (TDRH) PROTOTYPE PROJECT

    Science.gov (United States)

    The intended results of this disaster recovery shelter prototype project are first, to address the urgent need for improved transitional housing stock for future disaster recovery efforts; second, to provide architecture and engineering students with an opportunity to learn fr...

  15. Prototype superconducting radio-frequency cavity for LEP

    CERN Multimedia

    1985-01-01

    This niobium superconducting cavity was part of the prototype stages for an upgrade to LEP, known as LEP-2. Superconducting cavities would eventually replace the traditional copper cavities and allow beam energies of 100 GeV.

  16. CSNS/RCS LLRF remote control system prototype

    International Nuclear Information System (INIS)

    In the CSNS/RCS LLRF remote control prototype based on EPICS/vxWorks, one CPU board controls eight FPGA-based I/O board via cPCI bus, and transfer data to host computer to display. Meanwhile, host computer can also transfer control signal and waveform data downstream. Test result indicates that this prototype will satisfy the requirement of CSNS/RCS LLRF control system. (authors)

  17. A prototype for the LHCb silicon tracker data readout system

    CERN Document Server

    Vollhardt, A

    2003-01-01

    This note reports the development of the digital optical readout system for the LHCb Silicon Tracker. We describe the migration from the first functional prototype to a full prototype with all of the used components planned for use in the final detector system. We also present cable studies done for the analogue copper transmission line needed between the front-end amplifiers and the digitizing stage. Price estimates for full production quantities are given.

  18. A Risk Assessment Model for Software Prototyping Projects

    OpenAIRE

    Nogueira, Juan Carlos; Luqi; Bhattacharya, Swapan

    2000-01-01

    Software prototyping processes have contributed to develop cheaper, faster and more reliable products. However, despite the advances in technology, little progress has been done in improving the management of software prototyping development projects. Research shows that 45 percent of all the causes for delayed software deliveries are related to organizational issues [1]. This paper addresses the risk assessment issue, introducing metrics and a model that can be integr...

  19. Forest fire prediction using fuzzy prototypical knowledge discovery

    OpenAIRE

    Olivas Varela, José Ángel; Romero, Francisco Pacual

    2000-01-01

    An application of Zadeh’s prototype theory in the Knowledge Acquisition process, is presented here, and as a practical example, to define a method for predicting the evolution of the forest fire occurrence-danger rate in INCEND-IA: A KBS for prediction and decision support in fighting against forest fires. This method then allows us to interpret any real cyclical situation using a previously discovered paradigm and define the current period. The FPKD (Fuzzy Prototypical Knowledge Discovery) i...

  20. Development and Analysis of Desiccant Enhanced Evaporative Air Conditioner Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Kozubal, E.; Woods, J.; Judkoff, R.

    2012-04-01

    This report documents the design of a desiccant enhanced evaporative air conditioner (DEVAP AC) prototype and the testing to prove its performance. Previous numerical modeling and building energy simulations indicate a DEVAP AC can save significant energy compared to a conventional vapor compression AC (Kozubal et al. 2011). The purposes of this research were to build DEVAP prototypes, test them to validate the numerical model, and identify potential commercialization barriers.