WorldWideScience

Sample records for clearinghouse incidents related

  1. Evidence-Based Clearinghouses in Social Work

    Science.gov (United States)

    Soydan, Haluk; Mullen, Edward J.; Alexandra, Laine; Rehnman, Jenny; Li, You-Ping

    2010-01-01

    Objectives: The purpose of this article is to describe several evidence-based clearinghouses focused on social work and related intervention outcomes, placing them in the context of how such clearinghouses can contribute to research dissemination to foster effective, evidence-based practice. Method: The study employed an analysis of data provided…

  2. FFCAct Clearinghouse, Directory of abstracts. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Harwood, T.

    1994-05-01

    The Federal Facility Compliance Act (FFCAct) Clearinghouse is a card catalog of information about the FFCAct and its requirements for developing Site Treatment Plans (STP). The information available in the clearinghouse includes abstracts describing computer applications, technical reports, and a list of technical experts. Information can be accessed for use in responding to FFCAct requirements, and the clearinghouse provides search capabilities on particular topics and issues related to STP development. Appendix A includes: contacts from each site, for which contact has been made, who are developing STPs; the FFCAct Clearinghouse Fact Sheet and; additional hard copy forms to be used to populate the database. This report contains 50 abstracts related to the Radioactive Waste Technical Support Program.

  3. California Earthquake Clearinghouse: Advocating for, and Advancing, Collaboration and Technology Interoperability, Between the Scientific and Emergency Response Communities, to Produce Actionable Intelligence for Situational Awareness, and Decision Support

    Science.gov (United States)

    Rosinski, A.; Beilin, P.; Colwell, J.; Hornick, M.; Glasscoe, M. T.; Morentz, J.; Smorodinsky, S.; Millington, A.; Hudnut, K. W.; Penn, P.; Ortiz, M.; Kennedy, M.; Long, K.; Miller, K.; Stromberg, M.

    2015-12-01

    The Clearinghouse provides emergency management and response professionals, scientific and engineering communities with prompt information on ground failure, structural damage, and other consequences from significant seismic events such as earthquakes or tsunamis. Clearinghouse activations include participation from Federal, State and local government, law enforcement, fire, EMS, emergency management, public health, environmental protection, the military, public and non-governmental organizations, and private sector. For the August 24, 2014 S. Napa earthquake, over 100 people from 40 different organizations participated during the 3-day Clearinghouse activation. Every organization has its own role and responsibility in disaster response; however all require authoritative data about the disaster for rapid hazard assessment and situational awareness. The Clearinghouse has been proactive in fostering collaboration and sharing Essential Elements of Information across disciplines. The Clearinghouse-led collaborative promotes the use of standard formats and protocols to allow existing technology to transform data into meaningful incident-related content and to enable data to be used by the largest number of participating Clearinghouse partners, thus providing responding personnel with enhanced real-time situational awareness, rapid hazard assessment, and more informed decision-making in support of response and recovery. The Clearinghouse efforts address national priorities outlined in USGS Circular 1242, Plan to Coordinate NEHRP post-earthquake investigations and S. 740-Geospatial Data Act of 2015, Sen. Orrin Hatch (R-UT), to streamline and coordinate geospatial data infrastructure, maximizing geospatial data in support of the Robert T. Stafford Act. Finally, the US Dept. of Homeland Security, Geospatial Management Office, recognized Clearinghouse's data sharing efforts as a Best Practice to be included in the forthcoming 2015 HLS Geospatial Concept of Operations.

  4. Mercury Information Clearinghouse

    Energy Technology Data Exchange (ETDEWEB)

    Chad A. Wocken; Michael J. Holmes; Dennis L. Laudal; Debra F. Pflughoeft-Hassett; Greg F. Weber; Nicholas V. C. Ralston; Stanley J. Miller; Grant E. Dunham; Edwin S. Olson; Laura J. Raymond; John H. Pavlish; Everett A. Sondreal; Steven A. Benson

    2006-03-31

    The Canadian Electricity Association (CEA) identified a need and contracted the Energy & Environmental Research Center (EERC) to create and maintain an information clearinghouse on global research and development activities related to mercury emissions from coal-fired electric utilities. With the support of CEA, the Center for Air Toxic Metals{reg_sign} (CATM{reg_sign}) Affiliates, and the U.S. Department of Energy (DOE), the EERC developed comprehensive quarterly information updates that provide a detailed assessment of developments in the various areas of mercury monitoring, control, policy, and research. A total of eight topical reports were completed and are summarized and updated in this final CEA quarterly report. The original quarterly reports can be viewed at the CEA Web site (www.ceamercuryprogram.ca). In addition to a comprehensive update of previous mercury-related topics, a review of results from the CEA Mercury Program is provided. Members of Canada's coal-fired electricity generation sector (ATCO Power, EPCOR, Manitoba Hydro, New Brunswick Power, Nova Scotia Power Inc., Ontario Power Generation, SaskPower, and TransAlta) and CEA, have compiled an extensive database of information from stack-, coal-, and ash-sampling activities. Data from this effort are also available at the CEA Web site and have provided critical information for establishing and reviewing a mercury standard for Canada that is protective of environment and public health and is cost-effective. Specific goals outlined for the CEA mercury program included the following: (1) Improve emission inventories and develop management options through an intensive 2-year coal-, ash-, and stack-sampling program; (2) Promote effective stack testing through the development of guidance material and the support of on-site training on the Ontario Hydro method for employees, government representatives, and contractors on an as-needed basis; (3) Strengthen laboratory analytical capabilities through

  5. TRANSPORTATION INFORMATION CLEARINGHOUSE

    OpenAIRE

    Allen, Karin; DiJohn, Joseph; Misek, Shamus

    2005-01-01

    The Transportation Information Clearinghouse (TIC) Project was the result of collaboration among the Regional Transportation Authority, the Workforce Boards of Metropolitan Chicago and the Urban Transportation Center (UTC) at the University of Illinois at Chicago (UIC). The primary objective of the project was to identify privatelyprovided, employer-based, non-traditional transportation services in operation as well as specific information about these services in order for employers, Workforc...

  6. Great Lakes Initiative (GLI) Clearinghouse

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Great Lakes Initiative Toxicity Data Clearinghouse is a central location for information on criteria, toxicity data, exposure parameters and other supporting...

  7. C2-Related Incidents Reported by UAS Pilots

    Science.gov (United States)

    Hobbs, Alan; Cardoza, Colleen; Null, Cynthia

    2016-01-01

    It has been estimated that aviation accidents are typically preceded by numerous minor incidents arising from the same causal factors that ultimately produced the accident. Accident databases provide in-depth information on a relatively small number of occurrences, however incident databases have the potential to provide insights into the human factors of Remotely Piloted Aircraft System (RPAS) operations based on a larger volume of less-detailed reports. Currently, there is a lack of incident data dealing with the human factors of unmanned aircraft systems. An exploratory study is being conducted to examine the feasibility of collecting voluntary critical incident reports from RPAS pilots. Twenty-three experienced RPAS pilots volunteered to participate in focus groups in which they described critical incidents from their own experience. Participants were asked to recall (1) incidents that revealed a system flaw, or (2) highlighted a case where the human operator contributed to system resilience or mission success. Participants were asked to only report incidents that could be included in a public document. During each focus group session, a note taker produced a de-identified written record of the incident narratives. At the end of the session, participants reviewed each written incident report, and made edits and corrections as necessary. The incidents were later analyzed to identify contributing factors, with a focus on design issues that either hindered or assisted the pilot during the events. A total of 90 incidents were reported. This presentation focuses on incidents that involved the management of the command and control (C2) link. The identified issues include loss of link, interference from undesired transmissions, voice latency, accidental control transfer, and the use of the lost link timer, or lost link OK features.

  8. Worldwide development of national spatial data clearinghouses (2000-2005)

    NARCIS (Netherlands)

    Crompvoets, J.W.H.C.; Bregt, A.K.

    2006-01-01

    One of the key features of a national spatial data infrastructure is a national clearinghouse for spatial data, which can be regarded as the access network of a national spatial data infrastructure facilitating access to a nation¿s spatial data and related services. Between April 2000 and 2005, a lo

  9. Incident detection and isolation in drilling using analytical redundancy relations

    DEFF Research Database (Denmark)

    Willersrud, Anders; Blanke, Mogens; Imsland, Lars

    2015-01-01

    Early diagnosis of incidents that could delay or endanger a drilling operation for oil or gas is essential to limit field development costs. Warnings about downhole incidents should come early enough to allow intervention before it develops to a threat, but this is difficult, since false alarms...... must be avoided. This paper employs model-based diagnosis using analytical redundancy relations to obtain residuals which are affected differently by the different incidents. Residuals are found to be non-Gaussian - they follow a multivariate t-distribution - hence, a dedicated generalized likelihood...

  10. Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC) facilitates finding and comparing neuroimaging resources for functional and structural...

  11. The GEOSS Clearinghouse based on the GeoNetwork opensource

    Science.gov (United States)

    Liu, K.; Yang, C.; Wu, H.; Huang, Q.

    2010-12-01

    The Global Earth Observation System of Systems (GEOSS) is established to support the study of the Earth system in a global community. It provides services for social management, quick response, academic research, and education. The purpose of GEOSS is to achieve comprehensive, coordinated and sustained observations of the Earth system, improve monitoring of the state of the Earth, increase understanding of Earth processes, and enhance prediction of the behavior of the Earth system. In 2009, GEO called for a competition for an official GEOSS clearinghouse to be selected as a source to consolidating catalogs for Earth observations. The Joint Center for Intelligent Spatial Computing at George Mason University worked with USGS to submit a solution based on the open-source platform - GeoNetwork. In the spring of 2010, the solution is selected as the product for GEOSS clearinghouse. The GEOSS Clearinghouse is a common search facility for the Intergovernmental Group on Ea rth Observation (GEO). By providing a list of harvesting functions in Business Logic, GEOSS clearinghouse can collect metadata from distributed catalogs including other GeoNetwork native nodes, webDAV/sitemap/WAF, catalog services for the web (CSW)2.0, GEOSS Component and Service Registry (http://geossregistries.info/), OGC Web Services (WCS, WFS, WMS and WPS), OAI Protocol for Metadata Harvesting 2.0, ArcSDE Server and Local File System. Metadata in GEOSS clearinghouse are managed in a database (MySQL, Postgresql, Oracle, or MckoiDB) and an index of the metadata is maintained through Lucene engine. Thus, EO data, services, and related resources can be discovered and accessed. It supports a variety of geospatial standards including CSW and SRU for search, FGDC and ISO metadata, and WMS related OGC standards for data access and visualization, as linked from the metadata.

  12. Organizational Learning From Information System-Related Incidents

    OpenAIRE

    Rezazade Mehrizi, Mohammad Hosein

    2014-01-01

    Aquesta tesi analitza com les organitzacions intenten palanquejar l’experiència dels ISRI (information system-related incidents) per tal d’evitar la recurrència de fallades i reduir-ne els impactes. En conseqüència, per estudiar-ho s’adopta una perspectiva d’aprenentatge situat i una visió pràctica per tal de respondre la pregunta: “Com aprenen les organitzacions de SI dels seus principals incidents interns, relacionats amb els sistemes d’informació?” Mitjançant el disseny d’un cas múltip...

  13. 33 CFR 273.18 - Clearinghouse coordination.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Clearinghouse coordination. 273.18 Section 273.18 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE AQUATIC PLANT CONTROL § 273.18 Clearinghouse coordination. Procedures prescribed...

  14. Analysis and evolution of human related Nuclear Power Plant incidents

    International Nuclear Information System (INIS)

    The present study aims at developing an integrated system that will permit a systematic analysis and evaluation of human related incidents with the purpose of unveil their underlying causal factors and identify specific hierarchical countermeasures. It is given a Summary Report Form containing a brief description of the event sequence, which can serve as material for subsequent analysis and activities aimed at promoting plant operation safety. 1 Fig., 1 Tab., 4 Refs

  15. National Spatial Data Clearinghouses: Worldwide development and impact

    OpenAIRE

    Crompvoets, J.W.H.C.

    2006-01-01

    Over the last few years many countries have spent considerable resources on developing their own National Spatial Data Infrastructure (NSDI) in order to manage and utilise spatial data assets more efficiently, reduce the cost of data production, and eliminate duplication of data acquisition. One of the key features of an NSDI is the national clearinghouse for spatial data, which can be regarded as the access network of an NSDI facilitating access to a nation's spatial data and related service...

  16. Anesthesia-related critical incidents in the perioperative period in children : A proposal for an anesthesia-related reporting system for critical incidents in children

    NARCIS (Netherlands)

    De Graaff, Jurgen C.; Sarfo, Marie Christine; Van Wolfswinkel, Leo; van der Werff, Desiree B. M.; Schouten, Antonius N J

    2015-01-01

    Background The incidence, type and severity of anesthesia-related critical incidents during the perioperative phase has been investigated less in children than in adults. Aim The aim of the study was to identify and analyze anesthesia-related critical incidents in children to identify areas to impro

  17. 14-year incidence, progression, and visual morbidity of age-related maculopathy

    DEFF Research Database (Denmark)

    Hesgaard, Helena; Nielsen, Niels V; Vinding, Troels;

    2005-01-01

    To describe the 14-year incidence of age-related maculopathy (ARM) lesions and the related visual loss.......To describe the 14-year incidence of age-related maculopathy (ARM) lesions and the related visual loss....

  18. National water-information clearinghouse activities; ground-water perspective

    Science.gov (United States)

    Haupt, C.A.; Jensen, R.A.

    1988-01-01

    The US Geological Survey (USGS) has functioned for many years as an informal clearinghouse for water resources information, enabling users to access groundwater information effectively. Water resources clearinghouse activities of the USGS are conducted through several separate computerized water information programs that are involved in the collection, storage, retrieval, and distribution of different types of water information. The following USGS programs perform water information clearinghouse functions and provide the framework for a formalized National Water-Information Clearinghouse: (1) The National Water Data Exchange--a nationwide confederation of more than 300 Federal, State, local, government, academic, and private water-oriented organizations that work together to improve access to water data; (2) the Water Resources Scientific Information Center--acquires, abstracts, and indexes the major water-resources-related literature of the world, and provides this information to the water resources community; (3) the Information Transfer Program--develops innovative approaches to transfer information and technology developed within the USGS to audiences in the public and private sectors; (4) the Hydrologic Information Unit--provides responses to a variety of requests, both technical and lay-oriented, for water resources information , and helps efforts to conduct water resources research; (5) the Water Data Storage and Retrieval System--maintains accessible computerized files of hydrologic data collected nationwide, by the USGS and other governmental agencies, from stream gaging stations, groundwater observation wells, and surface- and groundwater quality sampling sites; (6) the Office of Water Data Coordination--coordinate the water data acquisition activities of all agencies of the Federal Government, and is responsible for the planning, design, and inter-agency coordination of a national water data and information network; and (7) the Water Resources Research

  19. Ozone depletion, related UVB changes and increased skin cancer incidence

    Science.gov (United States)

    Kane, R. P.

    1998-03-01

    Stratospheric ozone at middle latitudes shows a seasonal variation of about +/-20%, a quasi-biennial oscillation of 1-10% range and a long-term variation in which the level was almost steady up to about 1979 and declined thereafter to the present day by about 10%. These variations are expected to be reflected in solar UVB observed at the ground, but in an opposite direction. Thus UVB should have had a long-term increase of about 10-20%, which should cause an increase in skin cancer incidence of about 20-40%. Skin cancer incidence has increased all over the world, e.g. about 90% in USA during 1974-1990. It is popularly believed that this increase in skin cancer incidence is related to the recent ozone depletion. This seems to be incorrect, for two reasons. Firstly, the observed skin cancer increase is too large (90%) compared with the expected value (40%) from ozone depletion. Secondly, cancer does not develop immediately after exposure to solar UVB. The sunburns may occur within hours; but cancer development and detection may take years, even decades. Hence the observed skin cancer increase since 1974 (no data available for earlier periods) must have occurred due to exposure to solar UVB in the 1950s and 1960s, when there was no ozone depletion. Thus, the skin cancer increase must be attributed to harmful solar UVB levels existing even in the 1960s, accentuated later not by ozone depletion (which started only much later, by 1979) but by other causes, such as a longer human life span, better screening, increasing tendencies of sunbathing at beaches, etc., in affluent societies. On the other hand, the recent ozone depletion and the associated UVB increases will certainly take their toll; only that the effects will not be noticed now but years or decades from now. The concern for the future expressed in the Montreal Protocol for reducing ozone depletion by controlling CFC production is certainly justified, especially because increased UVB is harmful to animal and

  20. Gender-related traumatic deaths in Transkei: incidence and causes.

    Science.gov (United States)

    Meel, B L

    2003-07-01

    This study is unique in that it strives to unfold, perhaps for the first time, the problem of female mortality due to trauma in the Transkei region of the Eastern Cape Province of South Africa. This study was carried out in the Umtata and Ngqeleni magisterial districts which have a combined population of about 400,000. Most of the people have very few resources and have historically relied on money repatriated by migrant workers. The objective was to establish the incidence and the causes of deaths due to gender-related trauma and to formulate recommendations which could probably help prevent or reduce these deaths. The study reviewed cases of female traumatic death during the period January 1993 to December 1999 that were brought to the mortuary in Umtata General Hospital (UGH). There were 1,054 (23%) traumatic deaths recorded in females between 1993 and 1999. Of these 486 (28%) were related to motor vehicle collisions, 219 (18%) due to gunshot injuries, 152 (19%) due to stab wounds and 139 (21%) as a result of blunt trauma. The male to female ratio was 3.3:1 in traumatic deaths. In homicides the male:female ratio was 4.4:1, gunshot 4.5:1, stab 4.2:1 and blunt injuries 3.7:1. In motor vehicle collisions (MVC's) the ratio was 2.5:1. There is an increasing incidence of traumatic deaths in women. Gun shot injuries are the commonest among traumatic deaths in females. This article recommends stricter measures to protect women in the form of legislation. Social uplifting and economic support should be carried out as part of the process of social change. In this case educating the entire community is necessary to safeguard women and their future survival.

  1. Evolution of the ERIC Clearinghouse on Urban Disadvantaged

    Science.gov (United States)

    Smith, Paul M., Jr.; Jablonsky, Adelaide

    1970-01-01

    Describes the scope, function, and history of the ERIC Clearinghouse on Urban Disadvantaged (ERIC-UD). This clearinghouse was formerly the Information Retrieval Center on the Disadvantaged (IRCD). (DE)

  2. 19 CFR 24.26 - Automated Clearinghouse credit.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Automated Clearinghouse credit. 24.26 Section 24... THE TREASURY CUSTOMS FINANCIAL AND ACCOUNTING PROCEDURE § 24.26 Automated Clearinghouse credit. (a) Description. Automated Clearinghouse (ACH) credit is an optional payment method that allows a payer...

  3. Incidence and prevalence of pregnancy-related heart disease.

    Science.gov (United States)

    Sliwa, Karen; Böhm, Michael

    2014-03-15

    Worldwide, the numbers of women who have a pre-existing cardiovascular disease or develop cardiac problems during pregnancy are increasing and, due to the lack of evidenced-based data, this provides challenges for the treating physician. Cardiovascular disease in pregnancy is a complex topic as women can present either pre- or post-partum, due to a pre-existing heart disease such as operated on or unoperated on congenital heart disease, valvular heart disease, chronic hypertension, or familial dilated cardiomyopathy. Women often present with symptoms and signs of acute heart failure. On the other hand, there are diseases which are directly related to pregnancy, such as hypertensive disorders of pregnancy and peripartum cardiomyopathy, or where pregnancy increases risk of a disease as, for example, the risk of myocardial infarction. These diseases can have long-term implications to the life of the affected women and their families. There is, in particular, a paucity of data from developing countries of this unique disease pattern and its presentations. This review summarizes the current knowledge of the incidence and prevalence of pregnancy-related cardiovascular disease in women presenting pre- or post-partum. PMID:24459193

  4. Incidence and prevalence of pregnancy-related heart disease.

    Science.gov (United States)

    Sliwa, Karen; Böhm, Michael

    2014-03-15

    Worldwide, the numbers of women who have a pre-existing cardiovascular disease or develop cardiac problems during pregnancy are increasing and, due to the lack of evidenced-based data, this provides challenges for the treating physician. Cardiovascular disease in pregnancy is a complex topic as women can present either pre- or post-partum, due to a pre-existing heart disease such as operated on or unoperated on congenital heart disease, valvular heart disease, chronic hypertension, or familial dilated cardiomyopathy. Women often present with symptoms and signs of acute heart failure. On the other hand, there are diseases which are directly related to pregnancy, such as hypertensive disorders of pregnancy and peripartum cardiomyopathy, or where pregnancy increases risk of a disease as, for example, the risk of myocardial infarction. These diseases can have long-term implications to the life of the affected women and their families. There is, in particular, a paucity of data from developing countries of this unique disease pattern and its presentations. This review summarizes the current knowledge of the incidence and prevalence of pregnancy-related cardiovascular disease in women presenting pre- or post-partum.

  5. Smart Grid Information Clearinghouse (SGIC)

    Energy Technology Data Exchange (ETDEWEB)

    Rahman, Saifur [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States)

    2014-08-31

    Since the Energy Independence and Security Act of 2007 was enacted, there has been a large number of websites that discusses smart grid and relevant information, including those from government, academia, industry, private sector and regulatory. These websites collect information independently. Therefore, smart grid information was quite scattered and dispersed. The objective of this work was to develop, populate, manage and maintain the public Smart Grid Information Clearinghouse (SGIC) web portal. The information in the SGIC website is comprehensive that includes smart grid information, research & development, demonstration projects, technical standards, costs & benefit analyses, business cases, legislation, policy & regulation, and other information on lesson learned and best practices. The content in the SGIC website is logically grouped to allow easily browse, search and sort. In addition to providing the browse and search feature, the SGIC web portal also allow users to share their smart grid information with others though our online content submission platform. The Clearinghouse web portal, therefore, serves as the first stop shop for smart grid information that collects smart grid information in a non-bias, non-promotional manner and can provide a missing link from information sources to end users and better serve users’ needs. The web portal is available at www.sgiclearinghouse.org. This report summarizes the work performed during the course of the project (September 2009 – August 2014). Section 2.0 lists SGIC Advisory Committee and User Group members. Section 3.0 discusses SGIC information architecture and web-based database application functionalities. Section 4.0 summarizes SGIC features and functionalities, including its search, browse and sort capabilities, web portal social networking, online content submission platform and security measures implemented. Section 5.0 discusses SGIC web portal contents, including smart grid 101, smart grid projects

  6. Incident Diabetes in Relation to Weight Patterns During Middle Age

    OpenAIRE

    Waring, Molly E.; Charles B Eaton; Lasater, Thomas M.; Lapane, Kate L

    2010-01-01

    The authors examined the association between weight patterns during middle age and incident type 2 diabetes mellitus using a subset (n = 1,476) of the Framingham Heart Study original cohort limited-access data set (1948–2003). Participants diagnosed with diabetes before age 50 years were excluded. A functional principal components analysis of body mass index from age 40 years to age 50 years was used to define weight patterns in terms of overall weight status (normal weight, overweight, or ob...

  7. FFCAct Clearinghouse, directory of abstracts: Radioactive waste technical support program. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-10-01

    The Federal Facility Compliance Act (FFCAct) Clearinghouse is a card catalog of information about the FFCAct and its requirements for developing Site Treatment Plans (STP). The information available in the clearinghouse includes abstracts describing computer applications, technical reports, and a list of technical experts. This report contains 61 abstracts from the database relating to radioactive waste management. The clearinghouse includes information on characterization, retrieval, treatment, storage, and disposal elements of waste management as they relate to the FFCAct and the treatment of mixed wastes. Subject areas of information being compiled include: commercial treatment capabilities; listings of technical experts for assistance in selecting and evaluating treatment options and technologies; mixed waste data and treatability groups; guidance on STP development; life-cycle costs planning estimates for facilities; references to documentation on available technologies and technology development activities; Waste Acceptance Criteria (WAC) for treatment facilities; regulatory, health and safety issues associated with treatment facilities and technologies; and computer databases, applications, and models for identifying and evaluating treatment facilities and technologies. Access to the FFCAct clearinghouse is available to the DOE and its DOE contractors involved in STP development and other FFCAct activities.

  8. The Higher Education Clearinghouse for Space Sciences

    Science.gov (United States)

    Dalton, H.; Cobabe-Ammann, E. A.; Shipp, S. S.

    2011-12-01

    The Higher Education Clearinghouse (HECl) is a searchable database of undergraduate classroom materials for faculty teaching planetary sciences and solar and space physics at both the introductory and upper division levels. Modeled after the highly successful SERC clearinghouse for geosciences assets, HECl was designed for easy submission of classroom assets - from homeworks and computer interactives to laboratories and demonstrations. All materials are peer-reviewed before posting, and authors adhere to the Creative Commons Attribution (CC BY). HECl materials are automatically cross-posted to other digital libraries (e.g., ComPADRE) and virtual higher education communities (e.g., Connexions). In addition to classroom materials, HECl provides news and information about educational research and best practices, funding opportunities, and ongoing efforts and collaborations for undergraduate education.

  9. Expansion and Enhacement of the Wyoming Coalbed Methane Clearinghouse Website to the Wyoming Energy Resources Information Clearinghouse.

    Energy Technology Data Exchange (ETDEWEB)

    Hulme, Diana [Univ. of Wyoming, Laramie, WY (United States); Hamerlinck, Jeffrey [Univ. of Wyoming, Laramie, WY (United States); Bergman, Harold [Univ. of Wyoming, Laramie, WY (United States); Oakleaf, Jim [Univ. of Wyoming, Laramie, WY (United States)

    2010-03-25

    Energy development is expanding across the United States, particularly in western states like Wyoming. Federal and state land management agencies, local governments, industry and non-governmental organizations have realized the need to access spatially-referenced data and other non-spatial information to determine the geographical extent and cumulative impacts of expanding energy development. The Wyoming Energy Resources Information Clearinghouse (WERIC) is a web-based portal which centralizes access to news, data, maps, reports and other information related to the development, management and conservation of Wyoming's diverse energy resources. WERIC was established in 2006 by the University of Wyoming's Ruckelshaus Institute of Environment and Natural Resources (ENR) and the Wyoming Geographic Information Science Center (WyGISC) with funding from the US Department of Energy (DOE) and the US Bureau of Land Management (BLM). The WERIC web portal originated in concept from a more specifically focused website, the Coalbed Methane (CBM) Clearinghouse. The CBM Clearinghouse effort focused only on coalbed methane production within the Powder River Basin of northeast Wyoming. The CBM Clearinghouse demonstrated a need to expand the effort statewide with a comprehensive energy focus, including fossil fuels and renewable and alternative energy resources produced and/or developed in Wyoming. WERIC serves spatial data to the greater Wyoming geospatial community through the Wyoming GeoLibrary, the WyGISC Data Server and the Wyoming Energy Map. These applications are critical components that support the Wyoming Energy Resources Information Clearinghouse (WERIC). The Wyoming GeoLibrary is a tool for searching and browsing a central repository for metadata. It provides the ability to publish and maintain metadata and geospatial data in a distributed environment. The WyGISC Data Server is an internet mapping application that provides traditional GIS mapping and analysis

  10. Work-related violence and incident use of psychotropics.

    Science.gov (United States)

    Madsen, Ida E H; Burr, Hermann; Diderichsen, Finn; Pejtersen, Jan H; Borritz, Marianne; Bjorner, Jakob B; Rugulies, Reiner

    2011-12-15

    Although the mental health consequences of domestic violence are well documented, empirical evidence is scarce regarding the mental health effects of violence in the workplace. Most studies have used data from small occupation-specific samples, limiting their generalizability. This article examines whether direct exposure to work-related violence is associated with clinically pertinent mental health problems, measured by purchases of psychotropics (antidepressants, anxiolytics, hypnotics), in a cross-occupational sample of 15,246 Danish employees free from using psychotropics at baseline. Self-reported data on work-related violence were merged with other data on purchases of medications through a national registry to estimate cause-specific hazard ratios during 3.6 years (1,325 days) of follow-up in the years 1996-2008. Outcomes were examined as competing risks, and analyses were adjusted for gender, age, cohabitation, education, income, social support from colleagues, social support from supervisor, and influence and quantitative demands at work. Work-related violence was associated with purchasing antidepressants alone (hazard ratio = 1.38, 95% confidence interval: 1.09, 1.75) or in combination with anxiolytics (hazard ratio = 1.74, 95% confidence interval: 1.13, 2.70) but not with purchasing anxiolytics or hypnotics only. The frequency of violent episodes and risk of caseness were unrelated. Work-related violence is associated with increased risk of clinically pertinent mental health problems. Reducing levels of work-related violence may help to prevent mental disorders in the working population. PMID:22038105

  11. Work-related violence and incident use of psychotropics

    DEFF Research Database (Denmark)

    Madsen, Ida E H; Burr, Hermann; Diderichsen, Finn;

    2011-01-01

    Although the mental health consequences of domestic violence are well documented, empirical evidence is scarce regarding the mental health effects of violence in the workplace. Most studies have used data from small occupation-specific samples, limiting their generalizability. This article examines...... whether direct exposure to work-related violence is associated with clinically pertinent mental health problems, measured by purchases of psychotropics (antidepressants, anxiolytics, hypnotics), in a cross-occupational sample of 15,246 Danish employees free from using psychotropics at baseline. Self......-reported data on work-related violence were merged with other data on purchases of medications through a national registry to estimate cause-specific hazard ratios during 3.6 years (1,325 days) of follow-up in the years 1996-2008. Outcomes were examined as competing risks, and analyses were adjusted for gender...

  12. 13 CFR 302.11 - Economic development information clearinghouse.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Economic development information... information clearinghouse. Pursuant to section 502 of PWEDA, EDA maintains an economic development information clearinghouse on its Internet Web site at http://www.eda.gov....

  13. Cancer incidence in the first-degree relatives of ovarian cancer patients.

    OpenAIRE

    Auranen, A; Pukkala, E.; Mäkinen, J.; Sankila, R.; Grénman, S.; Salmi, T.

    1996-01-01

    Cancer incidence was studied among 3072 first-degree relatives of 559 unselected ovarian cancer patients. Among cohort members there were 306 cancer cases. The overall cancer incidence was not increased: the standardised incidence ratio (SIR) in males was 0.9 (95% confidence interval 0.8-1.1) and in females 1.0 (0.8-1.1). The female relatives had a significantly increased risk for ovarian cancer (SIR 2.8, 1.8-4.2). The excess was attributable to sisters only (SIR 3.7, 2.3-5.7). The relative r...

  14. Critical incidents related to cardiac arrests reported to the Danish Patient Safety Database

    DEFF Research Database (Denmark)

    Andersen, Peter Oluf; Maaløe, Rikke; Andersen, Henning Boje

    2010-01-01

    Background Critical incident reports can identify areas for improvement in resuscitation practice. The Danish Patient Safety Database is a mandatory reporting system and receives critical incident reports submitted by hospital personnel. The aim of this study is to identify, analyse and categorize...... critical incidents related to cardiac arrests reported to the Danish Patient Safety Database. Methods The search terms “cardiac arrest” and “resuscitation” were used to identify reports in the Danish Patient Safety Database. Identified critical incidents were then classified into categories. Results One...... (n = 14; 11%), insufficient monitoring (n = 14; 11%), and medication error (n = 8; 7%). Conclusion Critical incidents related to cardiac arrest occur due to logistical, technical, teamworking and knowledge problems. These findings should be considered when planning education and implementing...

  15. Blood pressure, atherosclerosis, and the incidence of age-related maculopathy: the Rotterdam Study

    NARCIS (Netherlands)

    R. van Leeuwen (Redmer); M.K. Ikram (Kamran); J.R. Vingerling (Hans); J.C.M. Witteman (Jacqueline); P.T.V.M. de Jong (Paulus); A. Hofman (Albert)

    2003-01-01

    textabstractPURPOSE: To determine whether blood pressure and subclinical atherosclerosis are associated with incident age-related maculopathy (ARM). METHODS: The study was performed within the Rotterdam Study, a population-based, prospective cohort study in Rotterdam, The Netherlan

  16. Study on the scenario of the fire incident and related analysis

    International Nuclear Information System (INIS)

    On March 11,1997, Bituminization Demonstration Facility (BDF) of PNC Tokai Works made fire and explosion incident. As soon as the Incident Investigation Committee was established and began its activity just after the incident, we PNC also began our investigation of the damage, operational records, and everything considered useful to study cause of the incident to contribute to the committee. The cause is not yet completely clarified, but it is now believed that the fire occurred as a result of several unfavorable operational condition changes and that the cause is so complicated. Such operational condition changes are slower feed rate of waste solution, higher extruder torque, higher extruder temperature, introduction of precipitation from the bottom of waste solution vessel, and so on. Based on the investigation and study of much data, an assumable scenario has been developed. This report describes PNC 's view, as of middle October 1997, on the scenario of the fire incident and result of related analysis. (authors)

  17. BMI and obesity incidence in relation to food patterns of Polish older people

    DEFF Research Database (Denmark)

    Wadolowska, L.; Danowska-Oziewicz, M.; Niedzwiedzka, E.;

    2006-01-01

    BMI differentiation and obesity incidence in relation to food patterns of Polish older people were analysed. The research included 422 people aged 65+ years. 21 food patterns were separated by the factor analysis. On the basis of the self-reported body mass and height, the BMI and percentages...... of overweight or obese people were calculated. The increase of the BMI and overweight and obesity incidence for both sexes was unequivocally connected with eating rye. The increase of the BMI and overweight and obesity incidence depended among women on consuming pork meat and alcoholic beverages. For men...

  18. NASA's Eos ClearingHOuse: Integrating Access to Data Services

    Science.gov (United States)

    Burnett, M. T.; Pfister, R.; Wichman, K.

    2002-12-01

    ECHO (The Earth Observing System (EOS) ClearingHOuse) is being developed to provide flexibility to NASA's EOS to better meet the needs of the science community. ECHO is a clearinghouse of metadata, representing the data offerings of participating data providers. ECHO is being built with the goal of being an enabling system: Enabling a variety of Data Providers to participate. Enabling access to an ever-changing variety of Earth Science Data. Enabling access to an ever-growing suite of services, provided by the Science Community, which improves the usefulness of this data, including the binding of those services to the data represented in the clearinghouse. The purpose of this enabling philosophy is to support current Science efforts, but also to give the opportunity for creative organizations and individuals to break the traditional paradigm for discovering and leveraging Earth Science Data and Services in completely new ways. This presentation will focus on ECHO's approach to integrating Data Services from varied Service Providers, and facilitating access to those services by the user community. ECHO can be viewed as a typical Service oriented architecture. The fundamental interactions that it supports are (abstractly) Publish, Find and Bind. ECHO provides interfaces and mechanisms that allow organizations to publish their services. Using these interfaces, Service Providers can effectively "plug-in" their capabilities. There are mechanisms that allow the correlation of their service to the data types in the clearinghouse. ECHO's user community can find, or discover, services through a separate set of interfaces. Bindings are the mechanisms that support the invocation of services by ECHO's user community. ECHO supports binding either directly between the user and the service provider, or indirectly by using ECHO as a Service Broker. ECHO is supporting all of these Service capabilities by leveraging the contemporary (and evolving) "standards" of Web Services. Web

  19. Incidence and costs of bicycle-related traumatic brain injuries in the Netherlands.

    Science.gov (United States)

    Scholten, Annemieke C; Polinder, Suzanne; Panneman, Martien J M; van Beeck, Ed F; Haagsma, Juanita A

    2015-08-01

    The main cause of death and serious disability in bicycle accidents is traumatic brain injury (TBI). The aim of this population-based study was to assess the incidence and costs of bicycle-related TBI across various age groups, and in comparison to all bicycle-related injuries, to identify main risk groups for the development of preventive strategies. Data from the National Injury Surveillance System and National Medical Registration were used for all patients with bicycle-related injuries and TBI who visited a Dutch emergency department (ED) between 1998 and 2012. Demographics and national, weighted estimates of injury mechanism, injury severity and costs were analysed per age group. Direct healthcare costs and indirect costs were determined using the incidence-based Dutch Burden of Injury Model. Between 1998 and 2012, the incidence of ED treatments due to bicycle-related TBI strongly increased with 54%, to 43 per 100,000 persons in 2012. However, the incidence of all bicycle-related injuries remained stable, from 444 in 1998 to 456/100,000 in 2012. Incidence of hospital admission increased in both TBI (92%) and all injuries from cycling (71%). Highest increase in incidence of both ED treatments and hospital admissions was seen in adults aged 55+. The injury rate of TBI per kilometre travelled increased (44%) except in children, but decreased (-4%) for all injuries, showing a strong decrease in children (-36%) but an increase in men aged 25+, and women aged 15+. Total costs of bicycle-related TBI were €74.5 million annually. Although bicycle-related TBI accounted for 9% of the incidence of all ED treatments due to cycling, it accounted for 18% of the total costs due to all bicycle-related injuries (€410.7 million). Children and adolescents (aged 0-24) had highest incidence of ED treatments due to bicycle-related injuries. Men in the working population (aged 15-64) had highest indirect costs following injuries from cycling, including TBI. Older cyclists (aged

  20. Incidence of sports and recreation related injuries resulting in hospitalization in Wisconsin in 2000

    OpenAIRE

    Dempsey, R; Layde, P; Laud, P; Guse, C; Hargarten, S

    2005-01-01

    Objective: To describe the incidence and patterns of sports and recreation related injuries resulting in inpatient hospitalization in Wisconsin. Although much sports and recreation related injury research has focused on the emergency department setting, little is known about the scope or characteristics of more severe sports injuries resulting in hospitalization.

  1. Low tobacco-related cancer incidence in offspring of long-lived siblings

    DEFF Research Database (Denmark)

    Pedersen, Jacob K; Skytthe, Axel; McGue, Matt;

    2015-01-01

    interval) for offspring of long-lived individuals were 0.78 (0.70-0.86) for overall cancer; 0.66 (0.56-0.77) for tobacco-related cancer; 0.34 (0.22-0.51) for lung cancer; 0.88 (0.71-1.10) for breast cancer; 0.91 (0.62-1.34) for colon cancer. CONCLUSIONS: The low incidence of tobacco-related cancers in long......-lived families compared with non-tobacco-related cancers suggests that health behavior plays a central role in lower early cancer incidence in offspring of long-lived siblings in Denmark.......PURPOSE: Familial clustering of longevity is well documented and includes both genetic and other familial factors, but the specific underlying mechanisms are largely unknown. We examined whether low incidence of specific cancers is a mechanism for familial clustering of longevity. METHODS...

  2. The Higher Education Clearinghouse for Space Sciences (HECl)

    Science.gov (United States)

    Cobabe-Ammann, E.; Shipp, S. S.; Dalton, H.

    2012-03-01

    The Higher Education Clearinghouse (HECl) is a searchable database of undergraduate classroom materials for faculty teaching planetary sciences and solar and space physics at both the introductory and upper division levels.

  3. Regional variation in incidence for smoking and alcohol related cancers in Belgium.

    Science.gov (United States)

    Henau, Kris; Van Eycken, Elizabeth; Silversmit, Geert; Pukkala, Eero

    2015-02-01

    The prevalence of life habits may vary substantially within a country. Incidence maps of strongly related diseases can illustrate the distribution of these life style habits. In this study we explored the spatial variation in Belgium for different cancers related to alcohol and/or tobacco. From the Belgian Cancer Registry, municipality specific World Standardised incidence rates for the years 2004-2011 are used to create detailed smoothed cancer maps by subsite or histology for cancers of oral cavity, pharynx, larynx, oesophagus, liver and lung. Cancer incidence is compared both visually (from incidence maps) and with Poisson regression analysis using mortality from chronic liver disease and chronic obstructive pulmonary disease as a proxy for alcohol and tobacco prevalence, respectively. The incidence rates for oral cavity, pharyngeal and laryngeal cancer were comparable with the alcohol gradient. However, glottic cancer revealed a pattern that was more comparable with lung cancer. These two tumour types resembled more closely to the smoking pattern. Oesophageal cancer showed two patterns: squamous cell carcinoma was highly comparable with the background alcohol consumption, while adenocarcinoma was unrelated to one of our two proxies. Our approach and results are an encouraging example how data from a young cancer registry can be used in studies describing the regional cancer burden. The results can be useful for primary prevention to increase awareness for the public, authorities and health care professionals in specific subpopulations.

  4. Relations between Teachers' Professional and Religious Orientations and Their Behavior during Morally Critical Incidents.

    Science.gov (United States)

    van Veen, Klaas; Theunissen, Marielle; Sleegers, Peter; Bergen, Theo; Klaassen, Cees; Hermans, Chris

    2003-01-01

    Studied how teachers' professional and religious orientations relate to their behavior when confronted with morally critical incidents. Results for 452 teachers who completed a questionnaire suggest that both professional and religious orientations play a role and provide explanations for teachers' behavior. (SLD)

  5. Alcohol-Related Incident Guardianship and Undergraduate College Parties: Enhancing the Social Norms Marketing Approach

    Science.gov (United States)

    Gilbertson, Troy A.

    2006-01-01

    This randomized experiment examines the effects of contextual information on undergraduate college student's levels of alcohol-related incident guardianship at college parties. The research is conceptualized using routine activities theory and the theory of planned behavior. The experiment examines attitudinal variations about heavy drinking…

  6. Lipids, lipid genes, and incident age-related macular degeneration : the three continent age-related macular degeneration consortium

    NARCIS (Netherlands)

    Klein, Ronald; Myers, Chelsea E; Buitendijk, Gabriëlle H S; Rochtchina, Elena; Gao, Xiaoyi; de Jong, Paulus T V M; Sivakumaran, Theru A; Burlutsky, George; McKean-Cowdin, Roberta; Hofman, Albert; Iyengar, Sudha K; Lee, Kristine E; Stricker, Bruno H; Vingerling, Johannes R; Mitchell, Paul; Klein, Barbara E K; Klaver, Caroline C W; Wang, Jie Jin

    2014-01-01

    PURPOSE: To describe associations of serum lipid levels and lipid pathway genes to the incidence of age-related macular degeneration (AMD). DESIGN: Meta-analysis. METHODS: setting: Three population-based cohorts. population: A total of 6950 participants from the Beaver Dam Eye Study (BDES), Blue Mou

  7. Lipids, lipid genes, and incident age-related macular degeneration: The three continent age-related macular degeneration consortium

    NARCIS (Netherlands)

    R. Klein (Ronald); C.E. Myers (Chelsea); G.H.S. Buitendijk (Gabrielle); E. Rochtchina (Elena); X. Gao (Xiaoyi); P.T.V.M. de Jong (Paulus); T.A. Sivakumaran (Theru); G. Burlutsky (George); R. McKean-Cowdin (Roberta); A. Hofman (Albert); S.K. Iyengar (Sudha); K.E. Lee (Kristine); B.H. Stricker; J.R. Vingerling (Hans); P. Mitchell (Paul); B.E.K. Klein (Barbara); C.C.W. Klaver (Caroline); J.J. Wang (Jie Jin)

    2014-01-01

    textabstractPurpose To describe associations of serum lipid levels and lipid pathway genes to the incidence of age-related macular degeneration (AMD). Design Meta-analysis. Methods setting: Three population-based cohorts. population: A total of 6950 participants from the Beaver Dam Eye Study (BDES),

  8. Reduced Incidence of Foot-Related Hospitalisation and Amputation amongst Persons with Diabetes in Queensland, Australia.

    Directory of Open Access Journals (Sweden)

    Peter A Lazzarini

    Full Text Available To determine trends in the incidence of foot-related hospitalisation and amputation amongst persons with diabetes in Queensland (Australia between 2005 and 2010 that coincided with changes in state-wide ambulatory diabetic foot-related complication management.All data from cases admitted for the principal reason of diabetes foot-related hospitalisation or amputation in Queensland from 2005-2010 were obtained from the Queensland Hospital Admitted Patient Data Collection dataset. Incidence rates for foot-related hospitalisation (admissions, bed days used and amputation (total, minor, major cases amongst persons with diabetes were calculated per 1,000 person-years with diabetes (diabetes population and per 100,000 person-years (general population. Age-sex standardised incidence and age-sex adjusted Poisson regression models were also calculated for the general population.There were 4,443 amputations, 24,917 hospital admissions and 260,085 bed days used for diabetes foot-related complications in Queensland. Incidence per 1,000 person-years with diabetes decreased from 2005 to 2010: 43.0% for hospital admissions (36.6 to 20.9, 40.1% bed days (391 to 234, 40.0% total amputations (6.47 to 3.88, 45.0% major amputations (2.18 to 1.20, 37.5% minor amputations (4.29 to 2.68 (p < 0.01 respectively. Age-sex standardised incidence per 100,000 person-years in the general population also decreased from 2005 to 2010: 23.3% hospital admissions (105.1 to 80.6, 19.5% bed days (1,122 to 903, 19.3% total amputations (18.57 to 14.99, 26.4% major amputations (6.26 to 4.61, 15.7% minor amputations (12.32 to 10.38 (p < 0.01 respectively. The age-sex adjusted incidence rates per calendar year decreased in the general population (rate ratio (95% CI; hospital admissions 0.949 (0.942-0.956, bed days 0.964 (0.962-0.966, total amputations 0.962 (0.946-0.979, major amputations 0.945 (0.917-0.974, minor amputations 0.970 (0.950-0.991 (p < 0.05 respectively.There were significant

  9. Causal Factors and Adverse Events of Aviation Accidents and Incidents Related to Integrated Vehicle Health Management

    Science.gov (United States)

    Reveley, Mary S.; Briggs, Jeffrey L.; Evans, Joni K.; Jones, Sharon M.; Kurtoglu, Tolga; Leone, Karen M.; Sandifer, Carl E.

    2011-01-01

    Causal factors in aviation accidents and incidents related to system/component failure/malfunction (SCFM) were examined for Federal Aviation Regulation Parts 121 and 135 operations to establish future requirements for the NASA Aviation Safety Program s Integrated Vehicle Health Management (IVHM) Project. Data analyzed includes National Transportation Safety Board (NSTB) accident data (1988 to 2003), Federal Aviation Administration (FAA) incident data (1988 to 2003), and Aviation Safety Reporting System (ASRS) incident data (1993 to 2008). Failure modes and effects analyses were examined to identify possible modes of SCFM. A table of potential adverse conditions was developed to help evaluate IVHM research technologies. Tables present details of specific SCFM for the incidents and accidents. Of the 370 NTSB accidents affected by SCFM, 48 percent involved the engine or fuel system, and 31 percent involved landing gear or hydraulic failure and malfunctions. A total of 35 percent of all SCFM accidents were caused by improper maintenance. Of the 7732 FAA database incidents affected by SCFM, 33 percent involved landing gear or hydraulics, and 33 percent involved the engine and fuel system. The most frequent SCFM found in ASRS were turbine engine, pressurization system, hydraulic main system, flight management system/flight management computer, and engine. Because the IVHM Project does not address maintenance issues, and landing gear and hydraulic systems accidents are usually not fatal, the focus of research should be those SCFMs that occur in the engine/fuel and flight control/structures systems as well as power systems.

  10. Homocysteine Levels in Chronic Gastritis and Other Conditions: Relations to Incident Cardiovascular Disease and Dementia

    OpenAIRE

    Redéen, Stefan; Ryberg, Anna; Petersson, Fredrik; Eriksson, Olle; Nägga, Katarina; Borch, Kurt

    2009-01-01

    Background Homocysteine levels in circulation are determined by several factors and hyperhomocysteinemia is reportedly associated with cardiovascular diseases and dementia. The aim of this study is to determine the relation of chronic gastritis and other conditions to homocysteine levels and their relation to incident cardiovascular diseases and dementia. Methods An adult population-based cohort (N = 488) was screened for H. pylori infection, gastro-duodenitis (endoscopic biopsies), disease h...

  11. Person-related work and incident use of antidepressants: relations and mediating factors from the Danish work environment cohort study

    DEFF Research Database (Denmark)

    Madsen, Ida E H; Diderichsen, Finn; Burr, Hermann;

    2010-01-01

    Previous Danish studies have shown that employees who "work with people" (i.e., do person-related work) are at increased risk of hospitalization with a diagnosis of depression. However, these studies were purely register-based and consequently unable to point to factors underlying this elevated...... risk. This paper examines whether person-related work is associated with incident use of antidepressants, and whether this association is mediated by several work environment exposures....

  12. Hazard identification for equipment-related fatal incidents in the U.S.underground coal mining

    Institute of Scientific and Technical Information of China (English)

    Vladislav Kecojevic; Zainalabidin Md Nor

    2009-01-01

    Based on the number of fatalities per year,a persistent area of concern in mine safety continues to be equipment related.Data from the period 1995 through 2007 were studied in order to identify major hazards for underground mining equipment-related fatal incidents and to perform an analysis of those that occurred over the last 13 years.Reports on equipment-related fatal incidents were obtained from the Mine Safety and Health Ad-ministration (MSHA).The results show that underground mining equipment including con-tinuous miner, shuttle car, roof bolter, load-haul-dump (LHD), Iongwall and hoisting con-tributed to a total of 69 mining-related fatalities.The study reveals that the major hazard for continuous mining equipment-related fatal incidents is "Failure of victim to respect equipment working area", while the highest number of fatalities for shuttle car is attributed to the hazard "Failure of mechanical components." The study further reveals that the highest number of fatalities for roof bolter, LHD, and longwall are attributed to the hazards "Working under unsupported roof', "Failure of management to provide safe working condi-tions", and "Failure of mechanical components", respectively.It is determined that one fa-tality for the hoisting system is attributed to the hazard "Failure of mechanical components" and one to the hazard "Failure to follow safe maintenance procedure".Finally, approaches to prevention were also discussed in this paper.

  13. Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.

    Directory of Open Access Journals (Sweden)

    Carsten A Böger

    2011-09-01

    Full Text Available Family studies suggest a genetic component to the etiology of chronic kidney disease (CKD and end stage renal disease (ESRD. Previously, we identified 16 loci for eGFR in genome-wide association studies, but the associations of these single nucleotide polymorphisms (SNPs for incident CKD or ESRD are unknown. We thus investigated the association of these loci with incident CKD in 26,308 individuals of European ancestry free of CKD at baseline drawn from eight population-based cohorts followed for a median of 7.2 years (including 2,122 incident CKD cases defined as eGFR <60ml/min/1.73m(2 at follow-up and with ESRD in four case-control studies in subjects of European ancestry (3,775 cases, 4,577 controls. SNPs at 11 of the 16 loci (UMOD, PRKAG2, ANXA9, DAB2, SHROOM3, DACH1, STC1, SLC34A1, ALMS1/NAT8, UBE2Q2, and GCKR were associated with incident CKD; p-values ranged from p = 4.1e-9 in UMOD to p = 0.03 in GCKR. After adjusting for baseline eGFR, six of these loci remained significantly associated with incident CKD (UMOD, PRKAG2, ANXA9, DAB2, DACH1, and STC1. SNPs in UMOD (OR = 0.92, p = 0.04 and GCKR (OR = 0.93, p = 0.03 were nominally associated with ESRD. In summary, the majority of eGFR-related loci are either associated or show a strong trend towards association with incident CKD, but have modest associations with ESRD in individuals of European descent. Additional work is required to characterize the association of genetic determinants of CKD and ESRD at different stages of disease progression.

  14. [Work-related disability among postal employees: incidence, duration, and social security costs in 2008].

    Science.gov (United States)

    Mascarenhas, Flávia Alves Neves; Barbosa-Branco, Anadergh

    2014-06-01

    This study analyzed the characteristics of Brazilian postal workers that received sick leave benefits in 2008. The databases were from the Unified Benefits System (SUB) and the National Registry of Social Information (CNIS). The incidence rate was 556.5 benefits per 10,000 employees, and the leading causes of work-related sick leave were injuries, musculoskeletal disorders, and mental disorders. Areas most frequently reported in injuries were knees and legs, wrists and hands, ankles and feet, and shoulders and arms, with higher incidence rates in men. Women were more affected by musculoskeletal disorders and mental disorders. Average sick leave lasted longer in men, and the incidence of benefits increased with age. The States with the highest incidence rates were Mato Grosso do Sul, Goiás, and Santa Catarina, and security benefits averaged BRL 1,847.00. Postal work may involve additional risk of injuries to the limbs, due to the long distances carrying heavy weight, assault, and dog bites.

  15. Ambient air pollution exposure and the incidence of related health effects among racial/ethnic minorities

    Energy Technology Data Exchange (ETDEWEB)

    Nieves, L.A.; Wernette, D.R.

    1997-02-01

    Differences among racial and ethnic groups in morbidity and mortality rates for diseases, including diseases with environmental causes, have been extensively documented. However, documenting the linkages between environmental contaminants, individual exposures, and disease incidence has been hindered by difficulties in measuring exposure for the population in general and for minority populations in particular. After briefly discussing research findings on associations of common air pollutants with disease incidence, the authors summarize recent studies of radial/ethnic subgroup differences in incidence of these diseases in the US. They then present evidence of both historic and current patterns of disproportionate minority group exposure to air pollution as measured by residence in areas where ambient air quality standards are violated. The current indications of disproportionate potential exposures of minority and low-income populations to air pollutants represent the continuation of a historical trend. The evidence of linkage between disproportionate exposure to air pollution of racial/ethnic minorities and low-income groups and their higher rates of some air pollution-related diseases is largely circumstantial. Differences in disease incidence and mortality rates among racial/ethnic groups are discussed for respiratory diseases, cancers, and lead poisoning. Pollutants of concern include CO, Pb, SO{sub 2}, O{sub 3}, and particulates.

  16. The Incidence of Peripheral Catheter-Related Thrombosis in Surgical Patients

    Directory of Open Access Journals (Sweden)

    Amy Leung

    2016-01-01

    Full Text Available Background. Central venous catheters and peripherally inserted central catheters are well established risk factors for upper limb deep vein thrombosis. There is limited literature on the thrombosis rates in patients with peripheral catheters. A prospective observational study was conducted to determine the incidence of peripheral catheter-related thrombosis in surgical patients. Methods. Patients deemed high risk for venous thrombosis with a peripheral catheter were considered eligible for the study. An ultrasound was performed on enrolment into the study and at discharge from hospital. Participants were reviewed twice a day for clinical features of upper limb deep vein thrombosis during their admission and followed up at 30 days. Results. 54 patients were included in the study. The incidence of deep vein thrombosis and superficial venous thrombosis was 1.8% and 9.2%, respectively. All cases of venous thrombosis were asymptomatic. Risk factor analysis was limited by the low incidence of thrombosis. Conclusion. This study revealed a low incidence of deep vein thrombosis in surgical patients with peripheral catheters (1.8%. The study was underpowered; therefore the association between peripheral catheters and thrombosis is unable to be established. Future studies with larger sample sizes are required to determine the association between peripheral catheters and thrombosis.

  17. Incidence and risk factors of infections complications related to implantable venous-access ports

    Energy Technology Data Exchange (ETDEWEB)

    Shim, Ji Sue; Seo, Tae Seok; Song, Myung Gyu; Cha, In Ho; Kim, Jun Suk; Choi, Chul Won; Seo, Jae Hong; Oh, Sang Cheul [Korea University Guro Hospital, Korea University College of Medicine, Seoul (Korea, Republic of)

    2014-08-15

    The purpose of this study was to determine the incidence and risk factors of infections associated with implantable venous access ports (IVAPs.) From August 2003 through November 2011, 1747 IVAPs were placed in our interventional radiology suite. One hundred forty four IVAPs were inserted in patients with hematologic malignancy and 1603 IVAPs in patients with solid tumors. Among them, 40 ports (23 women and 17 men; mean age, 57.1 years; range, 13-83) were removed to treat port-related infections. We evaluated the incidence of port-related infection, patient characteristics, bacteriologic data, and patient progress. Univariable analyses (t test, chi-square test, and Fisher's exact test) and multiple logistic regression analyses were used to determine the risk factors for IVAP related infection. Overall, 40 (2.3%) of 1747 ports were removed for symptoms of infection with an incidence rate of 0.067 events/1000 catheter-days. According to the univariable study, the incidences of infection were seemingly higher in the patients who received the procedure during inpatient treatment (p = 0.016), the patients with hematologic malignancy (p = 0.041), and the patients receiving palliative chemotherapy (p = 0.022). From the multiple binary logistic regression, the adjusted odds ratios of infection in patients with hematologic malignancies and those receiving palliative chemotherapy were 7.769 (p = 0.001) and 4.863 (p = 0.003), respectively. Microorganisms were isolated from 26 (65%) blood samples, and two of the most causative organisms were found to be Staphylococcus (n = 10) and Candida species (n = 7). The underlying hematologic malignancy and the state of receiving palliative chemotherapy were the independent risk factors of IVAP-related infection.

  18. A Model for Relating Advertising Media Exposures to Purchase Incidence Behavior Patterns

    OpenAIRE

    Fred S. Zufryden

    1987-01-01

    A stochastic model is proposed to study the effect of advertising on consumer purchase dynamics by specifically relating the distribution of exposures, from a brand's media schedule, to brand purchase incidence behavior patterns over time. The approach is based on underlying individual consumer behavior assumptions that reflect the dynamics of exposures to advertising and brand purchase behavior, conditional on the level of advertising exposure received. Moreover, a population-based model is ...

  19. Age-related incidence of pineal calcification detected by computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Zimmerman, R.A.; Bilaniuk, L.T.

    1982-03-01

    The age-related incidence of detectable pineal calcification in 725 patients (age range, newborn-20 yrs) suggests that there is a relationship between calcification and the hormonal role played by the pineal gland in the regulation of sexual development. Pineal calcification (demonstrated by computed tomography (CT) on 8-mm-thick sections) in patients less than 6 years old should be looked upon with suspicion, and follow-up CT should be considered to exclude the possible development of a pineal neoplasm.

  20. Traffic-Related Air Pollution and Incident Type 2 Diabetes: Results from the SALIA Cohort Study

    OpenAIRE

    Krämer, Ursula; Herder, Christian; Sugiri, Dorothea; Strassburger, Klaus; Schikowski, Tamara; Ranft, Ulrich; Rathmann, Wolfgang

    2010-01-01

    Background Cross-sectional and ecological studies indicate that air pollution may be a risk factor for type 2 diabetes, but prospective data are lacking. Objective We examined the association between traffic-related air pollution and incident type 2 diabetes. Design Between 1985 and 1994, cross-sectional surveys were performed in the highly industrialized Ruhr district (West Germany); a follow-up investigation was conducted in 2006 using data from the Study on the Influence of Air Pollution o...

  1. Incidence and risk factors of infections complications related to implantable venous-access ports

    International Nuclear Information System (INIS)

    The purpose of this study was to determine the incidence and risk factors of infections associated with implantable venous access ports (IVAPs.) From August 2003 through November 2011, 1747 IVAPs were placed in our interventional radiology suite. One hundred forty four IVAPs were inserted in patients with hematologic malignancy and 1603 IVAPs in patients with solid tumors. Among them, 40 ports (23 women and 17 men; mean age, 57.1 years; range, 13-83) were removed to treat port-related infections. We evaluated the incidence of port-related infection, patient characteristics, bacteriologic data, and patient progress. Univariable analyses (t test, chi-square test, and Fisher's exact test) and multiple logistic regression analyses were used to determine the risk factors for IVAP related infection. Overall, 40 (2.3%) of 1747 ports were removed for symptoms of infection with an incidence rate of 0.067 events/1000 catheter-days. According to the univariable study, the incidences of infection were seemingly higher in the patients who received the procedure during inpatient treatment (p = 0.016), the patients with hematologic malignancy (p = 0.041), and the patients receiving palliative chemotherapy (p = 0.022). From the multiple binary logistic regression, the adjusted odds ratios of infection in patients with hematologic malignancies and those receiving palliative chemotherapy were 7.769 (p = 0.001) and 4.863 (p = 0.003), respectively. Microorganisms were isolated from 26 (65%) blood samples, and two of the most causative organisms were found to be Staphylococcus (n = 10) and Candida species (n = 7). The underlying hematologic malignancy and the state of receiving palliative chemotherapy were the independent risk factors of IVAP-related infection.

  2. Incidence of childhood leukemia in relation to proximity and general characteristics of different environmental exposure sources

    International Nuclear Information System (INIS)

    The role of the environment in the etiology of childhood acute leukemia (AL) is currently investigated. In this context, the aim of the present work is to study the association between the incidence of AL and the proximity of nuclear power plants (NPP) and to high voltage overhead power lines (HV OLs). At first, the geographical variations of AL have been studied at the Departement level. The cases included in the studies are all cases of AL of the French National Registry of Childhood Haemopatopoietic Malignancies on the studied periods: 1990-2004 for the study of incidence on Departements and 2002-2007 for the studies of association between incidence of AL and environmental exposure factors. Concerning those latter studies, a case-control approach has been used. The control sample, representative of the French pediatric population, contains 30,000 subjects and has been drawn by the INSEE. The precise localization of addresses of subjects and of exposure sources in relation with the type of sources is essential to build indicators of exposure reflecting the probability and intensity of exposure. * The study of AL by Departement has highlighted neither trend nor spatial structure in the incidence at this geographical level globally as well as by age, gender and subtype of leukemia.* On 2002-2007, on the contrary of on previous periods, the incidence of AL at less than 5 km from a NPP was nearly twice higher than expected, with the case-control study as well as with the incidence approach. This result was not specific to any age group, NPP, a type of NPP and was not associated with the geographic zoning of gaseous discharges of NPPs. * The study of the proximity to HV OLs highlighted an association between the incidence of AL and the close proximity (≤ 50 m) of lines of more than 225 kV, association which was restricted to children of less than 5 y.o. or living in non-urban areas; but not with the proximity to lines of less than 150 kV. (author)

  3. Lipids, Lipid Genes and Incident Age-Related Macular Degeneration: The Three Continent Age-Related Macular Degeneration Consortium

    Science.gov (United States)

    Klein, Ronald; Myers, Chelsea E.; Buitendijk, Gabriëlle H. S.; Rochtchina, Elena; Gao, Xiaoyi; de Jong, Paulus T. V. M.; Sivakumaran, Theru A.; Burlutsky, George; McKean-Cowdin, Roberta; Hofman, Albert; Iyengar, Sudha K.; Lee, Kristine E.; Stricker, Bruno H.; Vingerling, Johannes R.; Mitchell, Paul; Klein, Barbara E. K.; Klaver, Caroline C. W.; Wang, Jie Jin

    2014-01-01

    Purpose To describe associations of serum lipid levels and lipid pathway genes to the incidence of age-related macular degeneration (AMD). Design Meta-analysis. Methods Setting Three population-based cohorts. Population 6950 participants from the Beaver Dam Eye Study (BDES), Blue Mountains Eye Study (BMES) and Rotterdam Study (RS). Observation Procedures Participants were followed over 20 years and examined at 5-year intervals. Hazard ratios (HRs) associated with lipid levels per standard deviation above the mean or associated with each additional risk allele for each lipid pathway gene were calculated using random-effects inverse-weighted meta-analysis models, adjusting for known AMD risk factors. Main Outcome Measures Incidence of AMD. Results The average 5-year incidences of early AMD were 8.1%, 15.1%, and 13.0% in the BDES, BMES, and RS, respectively. Substantial heterogeneity in the effect of cholesterol and lipid pathway genes on the incidence and progression of AMD was evident when the data from the three studies were combined in meta-analysis. After correction for multiple comparisons, we did not find a statistically significant association between any of the cholesterol measures, statin use, or serum lipid genes and any of the AMD outcomes in the meta-analysis. Conclusion In a meta-analysis, there were no associations of cholesterol measures, history of statin use, or lipid pathway genes to the incidence and progression of AMD. These findings add to inconsistencies in earlier reports from our studies and others showing weak associations, no associations, or inverse associations of high-density lipoprotein cholesterol and total cholesterol with AMD. PMID:24879949

  4. Long-Term Exposure to Traffic-Related Air Pollution and Risk of Incident Atrial Fibrillation

    DEFF Research Database (Denmark)

    Monrad, Maria; Sajadieh, Ahmad; Christensen, Jeppe Schultz;

    2016-01-01

    of first-ever hospital admission for atrial fibrillation from enrolment to end of follow-up in 2011. For all cohort members, exposure to traffic-related air pollution assessed as nitrogen dioxide (NO2) and nitrogen oxides (NOx) was estimated at all present and historical residential addresses from 1984....... OBJECTIVES: The aim of this study was to evaluate the long-term impact of traffic-related air pollution on incidence of atrial fibrillation in the general population. METHODS: In the Danish Diet, Cancer, and Health cohort of 57,053 people aged 50-64 years at enrolment in 1993-1997, we identified 2,700 cases...

  5. Equipment-related incidents in the operating room: an analysis of occurrence, underlying causes and consequences for the clinical process

    NARCIS (Netherlands)

    Wubben, I.; Manen, van J.G.; Akker, van den B.J.; Vaartjes, S.R.; Harten, van W.H.

    2010-01-01

    Background: Equipment-related incidents in the operating room (OR) can affect quality of care. In this study, the authors determined the occurrence and effects on the care process in a large teaching hospital. - Methods: During a 4-week period, OR nurses reported equipment-related incidents during

  6. Polymorphisms in DNA repair genes, traffic-related polycyclic aromatic hydrocarbon exposure and breast cancer incidence.

    Science.gov (United States)

    Mordukhovich, Irina; Beyea, Jan; Herring, Amy H; Hatch, Maureen; Stellman, Steven D; Teitelbaum, Susan L; Richardson, David B; Millikan, Robert C; Engel, Lawrence S; Shantakumar, Sumitra; Steck, Susan E; Neugut, Alfred I; Rossner, Pavel; Santella, Regina M; Gammon, Marilie D

    2016-07-15

    Vehicular traffic polycyclic aromatic hydrocarbons (PAHs) have been associated with breast cancer incidence in epidemiologic studies, including our own. Because PAHs damage DNA by forming adducts and oxidative lesions, genetic polymorphisms that alter DNA repair capacity may modify associations between PAH-related exposures and breast cancer risk. Our goal was to examine the association between vehicular traffic exposure and breast cancer incidence within strata of a panel of nine biologically plausible nucleotide excision repair (NER) and base excision repair (BER) genotypes. Residential histories of 1,508 cases and 1,556 controls were assessed in the Long Island Breast Cancer Study Project between 1996 and 1997 and used to reconstruct residential traffic exposures to benzo[a]pyrene, as a proxy for traffic-related PAHs. Likelihood ratio tests from adjusted unconditional logistic regression models were used to assess multiplicative interactions. A gene-traffic interaction was evident (p = 0.04) for ERCC2 (Lys751); when comparing the upper and lower tertiles of 1995 traffic exposure estimates, the odds ratio (95% confidence interval) was 2.09 (1.13, 3.90) among women with homozygous variant alleles. Corresponding odds ratios for 1960-1990 traffic were also elevated nearly 2-3-fold for XRCC1(Arg194Trp), XRCC1(Arg399Gln) and OGG1(Ser326Cys), but formal multiplicative interaction was not evident. When DNA repair variants for ERCC2, XRCC1 and OGG1 were combined, among women with 4-6 variants, the odds ratios were 2.32 (1.22, 4.49) for 1995 traffic and 2.96 (1.06, 8.21) for 1960-1990 traffic. Our study is first to report positive associations between traffic-related PAH exposure and breast cancer incidence among women with select biologically plausible DNA repair genotypes. PMID:26946191

  7. Read Well[R]. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2010

    2010-01-01

    "Read Well"[R] is a reading curriculum for kindergarten and first-grade students whose goal is to increase students' literacy abilities. The program provides instruction in phonemic awareness, phonics, vocabulary, comprehension, and fluency. The What Works Clearinghouse (WWC) reviewed five studies on "Read Well"[R] for English language learners.…

  8. Dream Box Learning. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2013

    2013-01-01

    "DreamBox Learning" is a supplemental online mathematics program that provides adaptive instruction for students in grades K-5 and focuses on number and operations, place value, and number sense. The What Works Clearinghouse (WWC) identified one study of "DreamBox Learning" that both falls within the scope of the Elementary…

  9. Academy of READING®. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2014

    2014-01-01

    "Academy of READING"® is an online program that aims to improve students' reading skills using a structured and sequential approach to learning in five core areas--phonemic awareness, phonics, fluency, vocabulary, and comprehension. The What Works Clearinghouse (WWC) identified 38 studies of "Academy of READING"® for…

  10. The NLstart2run study : Incidence and risk factors of running-related injuries in novice runners

    NARCIS (Netherlands)

    Kluitenberg, B.; van Middelkoop, M.; Smits, D. W.; Verhagen, E.; Hartgens, F.; Diercks, R.; van der Worp, H.

    2015-01-01

    Running is a popular form of physical activity, despite of the high incidence of running-related injuries (RRIs). Because of methodological issues, the etiology of RRIs remains unclear. Therefore, the purposes of the study were to assess the incidence of RRIs and to identify risk factors for RRIs in

  11. An Examination of Commercial Aviation Accidents and Incidents Related to Integrated Vehicle Health Management

    Science.gov (United States)

    Reveley, Mary S.; Briggs, Jeffrey L.; Thomas, Megan A.; Evans, Joni K.; Jones, Sharon M.

    2011-01-01

    The Integrated Vehicle Health Management (IVHM) Project is one of the four projects within the National Aeronautics and Space Administration's (NASA) Aviation Safety Program (AvSafe). The IVHM Project conducts research to develop validated tools and technologies for automated detection, diagnosis, and prognosis that enable mitigation of adverse events during flight. Adverse events include those that arise from system, subsystem, or component failure, faults, and malfunctions due to damage, degradation, or environmental hazards that occur during flight. Determining the causal factors and adverse events related to IVHM technologies will help in the formulation of research requirements and establish a list of example adverse conditions against which IVHM technologies can be evaluated. This paper documents the results of an examination of the most recent statistical/prognostic accident and incident data that is available from the Aviation Safety Information Analysis and Sharing (ASIAS) System to determine the causal factors of system/component failures and/or malfunctions in U.S. commercial aviation accidents and incidents.

  12. Risk assessment for loader- and dozer-related fatal incidents in U.S. mining.

    Science.gov (United States)

    Md-Nor, Zainalabidin; Kecojevic, Vladislav; Komljenovic, Dragan; Groves, William

    2008-06-01

    The paper presents the results of research aimed at developing a risk assessment process that can be used to more thoroughly characterise risks associated with loader- and dozer-related fatal incidents in US mining. The assessment is based on historical data obtained from the US Mine Safety and Health Administration investigation reports, which includes 77 fatal incidents that occurred from 1995 to 2006. The Preliminary Hazard Assessment method is used in identifying and quantifying risks. Risk levels are then developed using a pre-established risk matrix that ranks them according to probability and severity. The resulting assigned risk value can then be used to prioritise risk control strategies. A total of 10 hazards were identified for loaders. The hazards 'failure to follow adequate maintenance procedure' and 'failure of mechanical/electrical/hydraulic components' were the most severe and frequent hazards and they fell into the category of 'high' risk. The same number of hazards was identified for dozers. The hazard 'failure to identify adverse site/geological conditions' was the most severe and frequent hazard and it fell into the category of 'high' risk. PMID:18642163

  13. Technical Review of Law Enforcement Standards and Guides Relative to Incident Management

    Energy Technology Data Exchange (ETDEWEB)

    Stenner, Robert D.; Salter, R.; Stanton, J. R.; Fisher, D.

    2009-03-24

    In an effort to locate potential law enforcement-related standards that support incident management, a team from the Pacific Northwest National Laboratory (PNNL) contacted representatives from the National Institute of Standards-Office of Law Enforcement Standards (NIST-OLES), National Institute of Justice (NIJ), Federal Bureau of Investigation (FBI), Secret Service, ASTM International committees that have a law enforcement focus, and a variety of individuals from local and regional law enforcement organizations. Discussions were held with various state and local law enforcement organizations. The NIJ has published several specific equipment-related law enforcement standards that were included in the review, but it appears that law enforcement program and process-type standards are developed principally by organizations that operate at the state and local level. Input is provided from state regulations and codes and from external non-government organizations (NGOs) that provide national standards. The standards that are adopted from external organizations or developed independently by state authorities are available for use by local law enforcement agencies on a voluntary basis. The extent to which they are used depends on the respective jurisdictions involved. In some instances, use of state and local disseminated standards is mandatory, but in most cases, use is voluntary. Usually, the extent to which these standards are used appears to depend on whether or not jurisdictions receive certification from a “governing” entity due to their use and compliance with the standards. In some cases, these certification-based standards are used in principal but without certification or other compliance monitoring. In general, these standards appear to be routinely used for qualification, selection for employment, and training. In these standards, the term “Peace Officer” is frequently used to refer to law enforcement personnel. This technical review of national law

  14. Relating increasing hantavirus incidences to the changing climate: the mast connection

    Directory of Open Access Journals (Sweden)

    Maes Piet

    2009-01-01

    Full Text Available Abstract Background Nephropathia epidemica (NE, an emerging rodent-borne viral disease, has become the most important cause of infectious acute renal failure in Belgium, with sharp increases in incidence occurring for more than a decade. Bank voles are the rodent reservoir of the responsible hantavirus and are known to display cyclic population peaks. We tried to relate these peaks to the cyclic NE outbreaks observed since 1993. Our hypothesis was that the ecological causal connection was the staple food source for voles, being seeds of deciduous broad-leaf trees, commonly called "mast". We also examined whether past temperature and precipitation preceding "mast years" were statistically linked to these NE outbreaks. Results Since 1993, each NE peak is immediately preceded by a mast year, resulting in significantly higher NE case numbers during these peaks (Spearman R = -0.82; P = 0.034. NE peaks are significantly related to warmer autumns the year before (R = 0.51; P Conclusion NE peaks in year 0 are induced by abundant mast formation in year-1, facilitating bank vole survival during winter, thus putting the local human population at risk from the spring onwards of year 0. This bank vole survival is further promoted by higher autumn temperatures in year-1, whereas mast formation itself is primed by higher summer temperatures in year-2. Both summer and autumn temperatures have been rising to significantly higher levels during recent years, explaining the virtually continuous epidemic state since 2005 of a zoonosis, considered rare until recently. Moreover, in 2007 a NE peak and an abundant mast formation occurred for the first time within the same year, thus forecasting yet another record NE incidence for 2008. We therefore predict that with the anticipated climate changes due to global warming, NE might become a highly endemic disease in Belgium and surrounding countries.

  15. Muscular strength is inversely related to prevalence and incidence of obesity in adult men.

    Science.gov (United States)

    Jackson, Allen W; Lee, Duck-Chul; Sui, Xuemei; Morrow, James R; Church, Timothy S; Maslow, Andrea L; Blair, Steven N

    2010-10-01

    The purpose of the study was to determine the relation between quintiles of muscular strength after adjustment for age and body weight, and excessive body fat (EBF) and excessive abdominal fat (EAF) when controlling for cardiorespiratory fitness (CRF) and other potential confounders. A two-phased cross-sectional and longitudinal study was conducted assessing the prevalence and incidence of EBF and EAF across quintiles of muscular strength. The sample included 3,258 men (mean age = 42.2 ± 8.9; weight (kg) = 81.2 ± 11.0; BMI = 25.3 ± 2.9; %fat = 19.4 ± 5.8; waist girth (cm) = 91.2 ± 9.0) who completed at least two clinical examinations as part of the Aerobics Center Longitudinal Study (ACLS). Muscular strength was assessed with tests of upper and lower body muscular strength using rack-mounted weights with participants placed into strength quintiles. CRF was measured by a modified Balke treadmill test, %fat via underwater weighing or seven-site skinfold measurements, and waist girth measured at the level of the umbilicus. EBF was defined as ≥25% and EAF was defined as >102 cm. There was a strong inverse gradient across quintiles of muscular strength for prevalence and incidence of EBF and EAF (P trend <0.01, each). With the lowest quintile serving as the referent, reductions in risk of EBF and EAF exceeded 70% for the highest strength quintile. Evidence suggests muscular strength may provide protection from EBF and EAF and their related comorbidities. PMID:19960002

  16. Incidence of Bacteriocins Produced by Food-Related Lactic Acid Bacteria Active towards Oral Pathogens

    Directory of Open Access Journals (Sweden)

    Konstantinos Papadimitriou

    2013-02-01

    Full Text Available In the present study we investigated the incidence of bacteriocins produced by 236 lactic acid bacteria (LAB food isolates against pathogenic or opportunistic pathogenic oral bacteria. This set of LAB contained several strains (≥17% producing bacteriocins active against food-related bacteria. Interestingly only Streptococcus macedonicus ACA-DC 198 was able to inhibit the growth of Streptococcus oralis, Streptococcus sanguinis and Streptococcus gordonii, while Lactobacillus fermentum ACA-DC 179 and Lactobacillus plantarun ACA-DC 269 produced bacteriocins solely against Streptococcus oralis. Thus, the percentage of strains that were found to produce bacteriocins against oral bacteria was ~1.3%. The rarity of bacteriocins active against oral LAB pathogens produced by food-related LAB was unexpected given their close phylogenetic relationship. Nevertheless, when tested in inhibition assays, the potency of the bacteriocin(s of S. macedonicus ACA-DC 198 against the three oral streptococci was high. Fourier-transform infrared spectroscopy combined with principal component analysis revealed that exposure of the target cells to the antimicrobial compounds caused major alterations of key cellular constituents. Our findings indicate that bacteriocins produced by food-related LAB against oral LAB may be rare, but deserve further investigation since, when discovered, they can be effective antimicrobials.

  17. Are work-related stressors associated with diagnosis of more advanced stages of incident breast cancers?

    DEFF Research Database (Denmark)

    Nielsen, Naja Rod; Stahlberg, Claudia; Strandberg-Larsen, Katrine;

    2008-01-01

    OBJECTIVE: To assess the relation between work-related stressors and breast cancer incidence and prognostic characteristics (estrogen receptor status, grade, lymph node status, size, stage) at the time of diagnosis. METHODS: The 18,932 women included in the Danish Nurse Cohort reported work......-related stressors in 1993 and again in 1999 and were followed until the end of 2003 in national registries. Prognostic characteristics were obtained from a clinical database and fewer than 0.1% were lost to follow up. RESULTS: During follow-up, 455 women were diagnosed with breast cancer. Neither women with high...... work pressure (HR = 1.17; 95% CI: 0.79, 1.73) nor women with self-reported low influence on work organization (0.98; 0.69, 1.39) or long working hours (0.93; 0.54, 1.58) were at higher risk of breast cancer than women with no such stressors. Women with high work tempo had a slightly higher risk...

  18. Breast Cancer-Related Arm Lymphedema: Incidence Rates, Diagnostic Techniques, Optimal Management and Risk Reduction Strategies

    International Nuclear Information System (INIS)

    As more women survive breast cancer, long-term toxicities affecting their quality of life, such as lymphedema (LE) of the arm, gain importance. Although numerous studies have attempted to determine incidence rates, identify optimal diagnostic tests, enumerate efficacious treatment strategies and outline risk reduction guidelines for breast cancer–related lymphedema (BCRL), few groups have consistently agreed on any of these issues. As a result, standardized recommendations are still lacking. This review will summarize the latest data addressing all of these concerns in order to provide patients and health care providers with optimal, contemporary recommendations. Published incidence rates for BCRL vary substantially with a range of 2–65% based on surgical technique, axillary sampling method, radiation therapy fields treated, and the use of chemotherapy. Newer clinical assessment tools can potentially identify BCRL in patients with subclinical disease with prospective data suggesting that early diagnosis and management with noninvasive therapy can lead to excellent outcomes. Multiple therapies exist with treatments defined by the severity of BCRL present. Currently, the standard of care for BCRL in patients with significant LE is complex decongestive physiotherapy (CDP). Contemporary data also suggest that a multidisciplinary approach to the management of BCRL should begin prior to definitive treatment for breast cancer employing patient-specific surgical, radiation therapy, and chemotherapy paradigms that limit risks. Further, prospective clinical assessments before and after treatment should be employed to diagnose subclinical disease. In those patients who require aggressive locoregional management, prophylactic therapies and the use of CDP can help reduce the long-term sequelae of BCRL.

  19. Breast Cancer-Related Arm Lymphedema: Incidence Rates, Diagnostic Techniques, Optimal Management and Risk Reduction Strategies

    Energy Technology Data Exchange (ETDEWEB)

    Shah, Chirag [Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI (United States); Vicini, Frank A., E-mail: fvicini@beaumont.edu [Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI (United States)

    2011-11-15

    As more women survive breast cancer, long-term toxicities affecting their quality of life, such as lymphedema (LE) of the arm, gain importance. Although numerous studies have attempted to determine incidence rates, identify optimal diagnostic tests, enumerate efficacious treatment strategies and outline risk reduction guidelines for breast cancer-related lymphedema (BCRL), few groups have consistently agreed on any of these issues. As a result, standardized recommendations are still lacking. This review will summarize the latest data addressing all of these concerns in order to provide patients and health care providers with optimal, contemporary recommendations. Published incidence rates for BCRL vary substantially with a range of 2-65% based on surgical technique, axillary sampling method, radiation therapy fields treated, and the use of chemotherapy. Newer clinical assessment tools can potentially identify BCRL in patients with subclinical disease with prospective data suggesting that early diagnosis and management with noninvasive therapy can lead to excellent outcomes. Multiple therapies exist with treatments defined by the severity of BCRL present. Currently, the standard of care for BCRL in patients with significant LE is complex decongestive physiotherapy (CDP). Contemporary data also suggest that a multidisciplinary approach to the management of BCRL should begin prior to definitive treatment for breast cancer employing patient-specific surgical, radiation therapy, and chemotherapy paradigms that limit risks. Further, prospective clinical assessments before and after treatment should be employed to diagnose subclinical disease. In those patients who require aggressive locoregional management, prophylactic therapies and the use of CDP can help reduce the long-term sequelae of BCRL.

  20. Potential safety-related incidents with possible applicability to a nuclear fuel reprocessing plant

    International Nuclear Information System (INIS)

    The occurrence of certain potential events in nuclear fuel reprocessing plants could lead to significant consequences involving risk to operating personnel or to the general public. This document is a compilation of such potential initiating events in nuclear fuel reprocessing plants. Possible general incidents and incidents specific to key operations in fuel reprocessing are considered, including possible causes, consequences, and safety features designed to prevent, detect, or mitigate such incidents

  1. Potential safety-related incidents with possible applicability to a nuclear fuel reprocessing plant

    Energy Technology Data Exchange (ETDEWEB)

    Perkins, W.C.; Durant, W.S.; Dexter, A.H.

    1980-12-01

    The occurrence of certain potential events in nuclear fuel reprocessing plants could lead to significant consequences involving risk to operating personnel or to the general public. This document is a compilation of such potential initiating events in nuclear fuel reprocessing plants. Possible general incidents and incidents specific to key operations in fuel reprocessing are considered, including possible causes, consequences, and safety features designed to prevent, detect, or mitigate such incidents.

  2. EVALUATION OF THE RELATIVE INCIDENCE OF ADVERSE EFFECTS LEADING TO TREATMENT DISCONTINUATION OF RECOMMENDED ANTIHYPERTENSIVE DRUGS

    Directory of Open Access Journals (Sweden)

    Yakubu Sani Ibn

    2013-06-01

    Full Text Available This study aimed at evaluating the incidence of adverse effects leading to treatment discontinuation of antihypertensive drugs within the same therapeutic class. Individual medical records were searched to identify those hypertensive patients who had been commenced on antihypertensive therapy during a 24-month period and who had subsequently for a reason(s discontinued the therapy. The results showed variation in discontinuation rates for drugs within same class, and that might be related to the relative frequency of specific adverse effects. Cough was the reason cited for discontinuation of angiotensin converting enzyme inhibitors, with linosopril appearing to be better tolerated than captopril (39% vs 48% ; peripheral oedema with calcium channel blockers, with amlodipine appearing to be better tolerated than nifedipine (29% vs 38% and bradycardia with beta adrenergic receptor blockers, with propranolol better tolerated than atenolol (0% vs 48%. Diuretics showed the lowest discontinuation rate (3.3% mainly due to hypokalemia, with thiazide better tolerated than frusemide (11% vs 43%. Prescribers should verify their use of antihypertensive drugs to ensure that they prescribe drugs with lower adverse effect rates, in order that patients with hypertension continue using the medication in the long term, thereby reducing the risk of developing cardiovascular complications associated with uncontrolled blood pressure.

  3. Malignancies in Wegener's granulomatosis: incidence and relation to cyclophosphamide therapy in a cohort of 293 patients

    DEFF Research Database (Denmark)

    Faurschou, Mikkel; Sørensen, Inge Juul; Mellemkjaer, Lene;

    2008-01-01

    To describe the incidence of malignancies in a cohort of Danish patients with Wegener's granulomatosis (WG) and to investigate the cancer risk associated with cyclophosphamide (CYC) -therapy in WG.......To describe the incidence of malignancies in a cohort of Danish patients with Wegener's granulomatosis (WG) and to investigate the cancer risk associated with cyclophosphamide (CYC) -therapy in WG....

  4. Relating multi-sequence longitudinal intensity profiles and clinical covariates in incident multiple sclerosis lesions.

    Science.gov (United States)

    Sweeney, Elizabeth M; Shinohara, Russell T; Dewey, Blake E; Schindler, Matthew K; Muschelli, John; Reich, Daniel S; Crainiceanu, Ciprian M; Eloyan, Ani

    2016-01-01

    The formation of multiple sclerosis (MS) lesions is a complex process involving inflammation, tissue damage, and tissue repair - all of which are visible on structural magnetic resonance imaging (MRI) and potentially modifiable by pharmacological therapy. In this paper, we introduce two statistical models for relating voxel-level, longitudinal, multi-sequence structural MRI intensities within MS lesions to clinical information and therapeutic interventions: (1) a principal component analysis (PCA) and regression model and (2) function-on-scalar regression models. To do so, we first characterize the post-lesion incidence repair process on longitudinal, multi-sequence structural MRI from 34 MS patients as voxel-level intensity profiles. For the PCA regression model, we perform PCA on the intensity profiles to develop a voxel-level biomarker for identifying slow and persistent, long-term intensity changes within lesion tissue voxels. The proposed biomarker's ability to identify such effects is validated by two experienced clinicians (a neuroradiologist and a neurologist). On a scale of 1 to 4, with 4 being the highest quality, the neuroradiologist gave the score on the first PC a median quality rating of 4 (95% CI: [4,4]), and the neurologist gave the score a median rating of 3 (95% CI: [3,3]). We then relate the biomarker to the clinical information in a mixed model framework. Treatment with disease-modifying therapies (p < 0.01), steroids (p < 0.01), and being closer to the boundary of abnormal signal intensity (p < 0.01) are all associated with return of a voxel to an intensity value closer to that of normal-appearing tissue. The function-on-scalar regression model allows for assessment of the post-incidence time points at which the covariates are associated with the profiles. In the function-on-scalar regression, both age and distance to the boundary were found to have a statistically significant association with the lesion intensities at some time point

  5. Fires and related incidents in Dubai, United Arab Emirates (2006–2013

    Directory of Open Access Journals (Sweden)

    Mohammad A. Alqassim

    2014-10-01

    Full Text Available Fire incidents in Dubai, United Arab Emirates, reported to the Forensic and Mechanical Engineering section of the Dubai Police Forensic Laboratory during 2006–2013 were reviewed. A detailed examination of more than 5000 incidents, representing a wide range of fire types is presented. Statistical comparisons on the type of incident and the cause and origin of the fire have been evaluated. City areas covered by each police station are also identified. The outcomes of the study indicate that more than one third of the total number of incidents involved motor vehicles and these accounted for more than half of all deliberately set fires in Dubai. A further one third of the incidents reviewed were in residential units. Electrical failures were shown to pose the highest risk of accidental fire and the Bur Dubai Police Station was the busiest in terms of fire investigation caseload.

  6. 45 CFR 2518.100 - What is the purpose of a Service-Learning Clearinghouse?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false What is the purpose of a Service-Learning...) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE SERVICE-LEARNING CLEARINGHOUSE § 2518.100 What is the purpose of a Service-Learning Clearinghouse? The Corporation will provide financial assistance, from...

  7. The incidence and prevalence of diabetes mellitus and related atherosclerotic complications in Korea: a National Health Insurance Database Study.

    Directory of Open Access Journals (Sweden)

    Bo Kyung Koo

    Full Text Available The incidence and prevalence of type 2 diabetes mellitus (T2DM and related macrovascular complications in Korea were estimated using the Health Insurance Review and Assessment (HIRA database from 2007-2011, which covers the claim data of 97.0% of the Korean population.T2DM, coronary artery disease (CAD, cerebrovascular disease (CVD, and peripheral artery disease (PAD were defined according to ICD-10 codes. We used the Healthcare Common Procedure Coding System codes provided by HIRA to identify associated procedures or surgeries. When calculating incidence, we excluded cases with preexisting T2DM within two years before the index year. A Poisson distribution was assumed when calculating 95% confidence intervals for prevalence and incidence rates.The prevalence of T2DM in Korean adults aged 20-89 years was 6.1-6.9% and the annual incidence rates of T2DM ranged from 9.5-9.8/1,000 person-year (PY during the study period. The incidence rates of T2DM in men and women aged 20-49 years showed decreasing patterns from 2009 to 2011 (P<0.001; by contrast, the incidence in subjects aged 70-79 years showed increased patterns from 2009 to 2011 (P<0.001. The incidence rates of CAD and CVD in patients newly diagnosed with T2DM were 18.84/1,000 PY and 11.32/1,000 PY, respectively, in the year of diagnosis. Among newly diagnosed individuals with T2DM who were undergoing treatment for PAD, 14.6% underwent angioplasty for CAD during the same period.Our study measured the national incidences of T2DM, CAD, CVD, and PAD, which are of great concern for public health. We also confirmed the relatively higher risk of CAD and CVD newly detected T2DM patients compared to the general population in Korea.

  8. Incidence and related risk factors of diabetic ketoacidosis in Guangdong type 1 diabetics

    Institute of Scientific and Technical Information of China (English)

    严晋华

    2013-01-01

    Objective To determine the incidence and the predictors of diabetes ketoacidosis(DKA)in Chinese type l diabetics so as to lay a foundation for better prevention and treatment.Methods For this cross-sectional study,a

  9. Incidence and determinants of nevirapine and efavirenz-related skin rashes in West Africans: nevirapine's epitaph?

    Directory of Open Access Journals (Sweden)

    Fred Stephen Sarfo

    Full Text Available Non-nucleoside reverse transcriptase inhibitor (NNRTI associated rash is common and frequently leads to discontinuation of NNRTIs. This study assessed the risk of developing rashes and discontinuing NNRTIs and associated factors in a large clinic in central Ghana. In this retrospective cohort study, clinical data were obtained in patients starting efavirenz or nevirapine between 2004-2010. Factors associated with rashes were explored using a multivariate Cox proportional hazards regression model. Of 3,999 patients who started NNRTI-based ART, 281 (7.0% experienced at least one episode of NNRTI-related rash with an incidence of 2.63 events/100 person-years, occurring in 10.2% and 5.6% of patients taking nevirapine and efavirenz respectively. Most rashes (94% were grade 1 or 2 and were reported a median of 2 months following initiation of ART. In multivariate analysis developing a rash was associated with nevirapine use (aHR 1.67, 95% CI 1.28-2.10, female gender (aHR of 1.39, 95% CI 1.01-1.92 and lower baseline CD4 counts (aHR 0.88, 95% CI 0.82-0.95 per 50 cells/mm³ increment. Patients with nevirapine-associated rash were 11 times more likely to discontinue treatment as patients with efavirenz-associated rash. In contrast to findings in other studies, NNRTI-associated rashes in Ghanaians appear more common in patients with lower baseline CD4 counts. Given the increased frequency of rashes with nevirapine and subsequent discontinuations in many patients, along with other treatment-limiting toxicities, this provides further impetus for the replacement of nevirapine by efavirenz as the first-line NNRTI treatment of choice in Africa.

  10. Relation between Ascites Syndrome Incidence and Infectious Bronchitis in Broiler Chickens by ELISA Method

    Directory of Open Access Journals (Sweden)

    Adel Feizi

    2011-12-01

    Full Text Available Infectious bronchitis is an acute viral disease with high contagious and mortality among chicks. The aim of this study was to survey of relation between ascites syndrome incidence and infectious bronchitis in broiler chickens by ELISA method in Iran. Eight Ross strain broiler farm affected by infectious bronchitis were selected in this study. Blood samples were gathered early stages of disease and blood sampling was repeated two times with seven days interval. ELISA serologic test was used for approving the determination of infectious bronchitis. In addition, in order to differential diagnosis of Newcastle and influenza (H9N2 some relevant experiments were conducted. The rate of mortality in any farm during rearing, autopsy and the cause of mortality were recorded. Ascites cases were calculated in terms of prevalence. The growth parameters, FCR, final weight, total consumption of grain at each farm were calculated and mentioned. Based on obtained results in this study, the mean rate of mortality caused by ascites syndrome has been increased meaningfully in herds affected by infectious bronchitis compared with control group. In eight understudied farms affected by infectious bronchitis, the mean rate of Ascites mortality was 3% such that the mean rate of Ascites mortality was 0.5% at previous periods. Based on relevant results also final weight mean in affected herds with infectious bronchitis was lower compared with previous periods. Meanwhile, FCR in affected herds with infectious bronchitis was high compared with healthy herds. In this research demonstrated that there is positive correlation between infectious bronchitis and Ascites syndrome and the correlation is significant (p<0.05.

  11. Breast cancer incidence and mortality in the Nordic capitals, 1970-1998. Trends related to mammography screening programmes

    DEFF Research Database (Denmark)

    Törnberg, Sven; Kemetli, Levent; Lynge, Elsebeth;

    2006-01-01

    The aim of the present study was to relate the time trends in breast cancer incidence and mortality to the introduction of mammography screening in the Nordic capitals. Helsinki offered screening to women aged 50-59 starting in 1986. The other three capitals offered screening to women aged 50...

  12. Related Services Research for Students with Low-Incidence Disabilities: Implications for Speech-Language Pathologists in Inclusive Classrooms.

    Science.gov (United States)

    Giangreco, Michael F.

    2000-01-01

    This article summarizes a team process for making related services decisions called VISTA (Vermont Interdependent Services Team Approach) and nine research studies on the use and impact of VISTA with students with low incidence disabilities. It also addresses team size, consumer perspectives, and paraprofessional supports. Five major conclusions…

  13. Incidence and risk factors of running-related injuries during preparation for a 4-mile recreational running event

    NARCIS (Netherlands)

    Buist, I.; Bredeweg, S. W.; Bessem, B.; van Mechelen, W.; Lemmink, K. A. P. M.; Diercks, R. L.

    2010-01-01

    Objective In this study, the incidence and the sex-specific predictors of running-related injury (RRI) among a group of recreational runners training for a 4-mile running event were determined and identified, respectively. Design Prospective cohort study. Methods Several potential risk factors were

  14. Are health professionals' perceptions of patient safety related to figures on safety incidents?

    NARCIS (Netherlands)

    Martijn, L.M.; Harmsen, M.; Gaal, S.; Mettes, D.G.; Dulmen, S.A. van; Wensing, M.

    2013-01-01

    OBJECTIVE: The study aims to explore whether health care professionals' perceptions of patient safety in their practice were associated with the number of patient safety incidents identified in patient records. SETTING: Seventy primary care practices of general practice, general dental practice, mid

  15. Incidence and etiology of sports-related sudden cardiac death in Denmark - Implications for preparticipation screening

    DEFF Research Database (Denmark)

    Holst, Anders Gaarsdal; Winkel, Bo Gregers; Theilade, Juliane;

    2010-01-01

    SCD were found, 8 of which had antecedent symptoms. The incidence rate was 1.21 (95% confidence inrterval (CI): 0.68 to 2.00) per 100,000 athlete person-years. The most common autopsy findings were arrhythmogenic right ventricular cardiomyopathy (n = 4), sudden unexplained death (n = 4) and coronary artery...... disease (n = 2). The incidence of SCD in the general population age 12- to 35 was 3.76 (95% CI: 3.42 to 4.14) per 100,000 person-years. Conclusion In Denmark, SrSCD is a rare occurrence and the incidence rate is lower than that of SCD in the general population. This may imply a low value...... this to the incidence of sudden cardiac death SCD in the background population. Methods Al 5,662 death certificates for decedents in the perio 2000 to 2006 in the age group 12 to 35 years in Denmark were read independently by 2 physicians to identify cases of SCD. Information from autopsy reports, selected hospital...

  16. Changing incidence and residual lifetime risk of common osteoporosis-related fractures

    DEFF Research Database (Denmark)

    Lauritzen, J B; Schwarz, Peter; Lund, B;

    1993-01-01

    Changes in incidence and lifetime risk of fractures are of major importance in the epidemiology of osteoporosis. We focused on hip fractures in women and men and on radial and humeral fractures in women. The study subjects comprised 4500 women and men 20 years old or more with fractures. In women...

  17. Propensity score methods for estimating relative risks in cluster randomized trials with low-incidence binary outcomes and selection bias.

    Science.gov (United States)

    Leyrat, Clémence; Caille, Agnès; Donner, Allan; Giraudeau, Bruno

    2014-09-10

    Despite randomization, selection bias may occur in cluster randomized trials. Classical multivariable regression usually allows for adjusting treatment effect estimates with unbalanced covariates. However, for binary outcomes with low incidence, such a method may fail because of separation problems. This simulation study focused on the performance of propensity score (PS)-based methods to estimate relative risks from cluster randomized trials with binary outcomes with low incidence. The results suggested that among the different approaches used (multivariable regression, direct adjustment on PS, inverse weighting on PS, and stratification on PS), only direct adjustment on the PS fully corrected the bias and moreover had the best statistical properties. PMID:24771662

  18. Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium.

    Directory of Open Access Journals (Sweden)

    Faye L Norby

    Full Text Available Several studies have shown associations between blood lipid levels and the risk of atrial fibrillation (AF. To test the potential effect of blood lipids with AF risk, we assessed whether previously developed lipid gene scores, used as instrumental variables, are associated with the incidence of AF in 7 large cohorts.We analyzed 64,901 individuals of European ancestry without previous AF at baseline and with lipid gene scores. Lipid-specific gene scores, based on loci significantly associated with lipid levels, were calculated. Additionally, non-pleiotropic gene scores for high-density lipoprotein cholesterol (HDLc and low-density lipoprotein cholesterol (LDLc were calculated using SNPs that were only associated with the specific lipid fraction. Cox models were used to estimate the hazard ratio (HR and 95% confidence intervals (CI of AF per 1-standard deviation (SD increase of each lipid gene score.During a mean follow-up of 12.0 years, 5434 (8.4% incident AF cases were identified. After meta-analysis, the HDLc, LDLc, total cholesterol, and triglyceride gene scores were not associated with incidence of AF. Multivariable-adjusted HR (95% CI were 1.01 (0.98-1.03; 0.98 (0.96-1.01; 0.98 (0.95-1.02; 0.99 (0.97-1.02, respectively. Similarly, non-pleiotropic HDLc and LDLc gene scores showed no association with incident AF: HR (95% CI = 1.00 (0.97-1.03; 1.01 (0.99-1.04.In this large cohort study of individuals of European ancestry, gene scores for lipid fractions were not associated with incident AF.

  19. Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium

    Science.gov (United States)

    Norby, Faye L.; Agarwal, Sunil K.; Arking, Dan E.; Chasman, Daniel L.; Chen, Lin Y.; Eijgelsheim, Mark; Engström, Gunnar; Franco, Oscar H.; Heeringa, Jan; Hindy, George; Hofman, Albert; Lutsey, Pamela L.; Magnani, Jared W.; McManus, David D.; Orho-Melander, Marju; Pankow, James S.; Rukh, Gull; Schulz, Christina-Alexandra; Uitterlinden, André G.; Albert, Christine M.; Benjamin, Emelia J.; Gudnason, Vilmundur; Smith, J. Gustav; Stricker, Bruno H. C.; Alonso, Alvaro

    2016-01-01

    Background Several studies have shown associations between blood lipid levels and the risk of atrial fibrillation (AF). To test the potential effect of blood lipids with AF risk, we assessed whether previously developed lipid gene scores, used as instrumental variables, are associated with the incidence of AF in 7 large cohorts. Methods We analyzed 64,901 individuals of European ancestry without previous AF at baseline and with lipid gene scores. Lipid-specific gene scores, based on loci significantly associated with lipid levels, were calculated. Additionally, non-pleiotropic gene scores for high-density lipoprotein cholesterol (HDLc) and low-density lipoprotein cholesterol (LDLc) were calculated using SNPs that were only associated with the specific lipid fraction. Cox models were used to estimate the hazard ratio (HR) and 95% confidence intervals (CI) of AF per 1-standard deviation (SD) increase of each lipid gene score. Results During a mean follow-up of 12.0 years, 5434 (8.4%) incident AF cases were identified. After meta-analysis, the HDLc, LDLc, total cholesterol, and triglyceride gene scores were not associated with incidence of AF. Multivariable-adjusted HR (95% CI) were 1.01 (0.98–1.03); 0.98 (0.96–1.01); 0.98 (0.95–1.02); 0.99 (0.97–1.02), respectively. Similarly, non-pleiotropic HDLc and LDLc gene scores showed no association with incident AF: HR (95% CI) = 1.00 (0.97–1.03); 1.01 (0.99–1.04). Conclusions In this large cohort study of individuals of European ancestry, gene scores for lipid fractions were not associated with incident AF. PMID:26999784

  20. The Self-Help Clearinghouse of Metropolitan Toronto: reflections on seven years of survival and beyond.

    Science.gov (United States)

    Fine, R; Hammett, C; Sernick, D; Steinhouse, K

    1995-01-01

    In May of 1987, Health and Welfare Canada awarded the Self-Help Clearinghouse of Metropolitan Toronto a three-year demonstration grant. Today, the Toronto Clearinghouse remains the only free-standing self-help resource of its kind in Canada and is a registered charitable organization whose mandate is to facilitate the growth and development of self-help/mutual-aid groups, networks, and resources. This paper describes the unique Toronto Clearinghouse model which from its earliest beginnings has been a partnership between the self-help community and interested and supportive professionals. The success of this model stems from its strong grassroots origins, respect for a community empowerment approach, and focused goals and objectives. Using information gleaned from the archival history of the Toronto Clearinghouse and through a series of interviews with past and current members of the Clearinghouse board of directors, program staff, and local self-help group members, the paper explains the "roller coaster ride" which has characterized the history of the Clearinghouse to date. Finally, the paper illustrates that while the achievement of financial stability has been an ongoing challenge in the face of variable community and political support, the Toronto Clearinghouse is, today, a strong centre of self-help activity and promotion, involved in a unique exercise to determine the role that self-help can play as a strategic component of an overall health and social services system-and with every reason to be optimistic about its future. PMID:10163396

  1. Pancreatic Cancer Incidence in Relation to Female Reproductive Factors: Iowa Women's Health Study

    Directory of Open Access Journals (Sweden)

    Anna E Prizment

    2007-01-01

    Full Text Available Objective Motivated by inconsistent literature, we evaluated the association between incident pancreatic cancer and reproductive characteristics. Design The Iowa Women’s Health Study is a large prospective population-based cohort followed from 1986 to 2003. Reproductive information was self-reported. Participants The study population comprised 37,459 women aged 55-69 years at baseline. Over 18 years, 228 incident pancreatic cancers were identified. Results In a multivariate-adjusted model there were no associations between incident pancreatic cancer and age at first birth, number of births, age at menarche, or use of hormones. There was a statistically significant inverse association between age at menopause and pancreatic cancer incidence. Compared to menopause less than 45 years, the hazard ratio of pancreatic cancer was 0.61 (95% CI, 0.40-0.94 for menopause at 45-49 years, 0.75 (95% CI, 0.51-1.09 for 50-54 years, and 0.35 (95% CI, 0.18-0.68 for menopause at 55 years or more (P trend=0.005. This association held after restricting the cohort to never smokers. The associations between pancreatic cancer and ages at natural and surgical menopause followed similar patterns. In a parallel fashion, risk of pancreatic cancer was decreased for women with intact ovaries compared to those who had oophorectomy: hazard ratio was 0.70 (95% CI, 0.50-0.99. Conclusions Our results indicate that older age at menopause is associated with reduced pancreatic cancer risk, but further research is warranted.

  2. Incidence and Risk Factors of Infectious Complications Related to Implantable Venous-Access Ports

    OpenAIRE

    Shim, Jisue; Seo, Tae-Seok; Song, Myung Gyu; Cha, In-Ho; Kim, Jun Suk; Choi, Chul Won; Seo, Jae Hong; Oh, Sang Cheul

    2014-01-01

    Objective The purpose of this study was to determine the incidence and risk factors of infections associated with implantable venous access ports (IVAPs). Materials and Methods From August 2003 through November 2011, 1747 IVAPs were placed in our interventional radiology suite. One hundred forty four IVAPs were inserted in patients with hematologic malignancy and 1603 IVAPs in patients with solid tumors. Among them, 40 ports (23 women and 17 men; mean age, 57.1 years; range, 13-83) were remov...

  3. Risk factors for bovine tuberculosis in low incidence regions related to the movements of cattle

    OpenAIRE

    Gates, M Carolyn; Volkova, Victoriya V.; Woolhouse, Mark EJ

    2013-01-01

    BackgroundBovine tuberculosis (bTB) remains difficult to eradicate from low incidence regions partly due to the imperfect sensitivity and specificity of routine intradermal tuberculin testing. Herds with unconfirmed reactors that are incorrectly classified as bTB-negative may be at risk of spreading disease, while those that are incorrectly classified as bTB-positive may be subject to costly disease eradication measures. This analysis used data from Scotland in the period leading to Officiall...

  4. Risk factors for bovine tuberculosis in low incidence regions related to the movements of cattle

    OpenAIRE

    Gates, M Carolyn; Volkova, Victoriya V.; Woolhouse, Mark EJ

    2013-01-01

    Background Bovine tuberculosis (bTB) remains difficult to eradicate from low incidence regions partly due to the imperfect sensitivity and specificity of routine intradermal tuberculin testing. Herds with unconfirmed reactors that are incorrectly classified as bTB-negative may be at risk of spreading disease, while those that are incorrectly classified as bTB-positive may be subject to costly disease eradication measures. This analysis used data from Scotland in the period leading to Official...

  5. Lithium in drinking water and the incidences of crimes, suicides, and arrests related to drug addictions.

    Science.gov (United States)

    Schrauzer, G N; Shrestha, K P

    1990-05-01

    Using data for 27 Texas counties from 1978-1987, it is shown that the incidence rates of suicide, homicide, and rape are significantly higher in counties whose drinking water supplies contain little or no lithium than in counties with water lithium levels ranging from 70-170 micrograms/L; the differences remain statistically significant (p less than 0.01) after corrections for population density. The corresponding associations with the incidence rates of robbery, burglary, and theft were statistically significant with p less than 0.05. These results suggest that lithium has moderating effects on suicidal and violent criminal behavior at levels that may be encountered in municipal water supplies. Comparisons of drinking water lithium levels, in the respective Texas counties, with the incidences of arrests for possession of opium, cocaine, and their derivatives (morphine, heroin, and codeine) from 1981-1986 also produced statistically significant inverse associations, whereas no significant or consistent associations were observed with the reported arrest rates for possession of marijuana, driving under the influence of alcohol, and drunkenness. These results suggest that lithium at low dosage levels has a generally beneficial effect on human behavior, which may be associated with the functions of lithium as a nutritionally-essential trace element. Subject to confirmation by controlled experiments with high-risk populations, increasing the human lithium intakes by supplementation, or the lithiation of drinking water is suggested as a possible means of crime, suicide, and drug-dependency reduction at the individual and community level.

  6. Rheumatoid arthritis and the incidence of influenza and influenza-related complications: a retrospective cohort study

    Directory of Open Access Journals (Sweden)

    Blumentals William A

    2012-08-01

    Full Text Available Abstract Background Patients with rheumatoid arthritis (RA are known to be at increased risk of infection, particularly if they are taking drugs with immunomodulatory effects. There is a need for more information on the risk of influenza in patients with RA. Methods A retrospective cohort study was carried out using data gathered from a large US commercial health insurance database (Thomson Reuters Medstat MarketScan from 1 January 2000 to 31 December 2007. Patients were ≥18 years of age, with at least two RA claims diagnoses. The database was scanned for incidence of seasonal influenza and its complications on or up to 30 days after an influenza diagnosis in RA patients and matched controls. Other factors accounted for included medical conditions, use of disease-modifying anti-rheumatic drugs (DMARDs, use of biological agents, influenza vaccination and high- or low-dose corticosteroids. Incidence rate ratios (IRRs were calculated for influenza and its complications in patients with RA. Results 46,030 patients with RA and a matching number of controls had a median age of 57 years. The incidence of influenza was higher in RA patients than in controls (409.33 vs 306.12 cases per 100,000 patient-years, and there was a 2.75-fold increase in incidence of complications in RA. Presence or absence of DMARDs or biologics had no significant effect. The adjusted IRR of influenza was statistically significant in patients aged 60–69 years, and especially among men. A significantly increased rate of influenza complications was observed in women and in both genders combined (but not in men only when all age groups were combined. In general, the risk of influenza complications was similar in RA patients not receiving DMARDs or biologics to that in all RA patients. Pneumonia rates were significantly higher in women with RA. Rates of stroke/myocardial infarction (MI were higher in men, although statistical significance was borderline. Conclusions RA is

  7. The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Birmingham C Laird

    2009-03-01

    Full Text Available Abstract Background Overweight and obese persons are at risk of a number of medical conditions which can lead to further morbidity and mortality. The primary objective of this study is to provide an estimate of the incidence of each co-morbidity related to obesity and overweight using a meta-analysis. Methods A literature search for the twenty co-morbidities identified in a preliminary search was conducted in Medline and Embase (Jan 2007. Studies meeting the inclusion criteria (prospective cohort studies of sufficient size reporting risk estimate based on the incidence of disease were extracted. Study-specific unadjusted relative risks (RRs on the log scale comparing overweight with normal and obese with normal were weighted by the inverse of their corresponding variances to obtain a pooled RR with 95% confidence intervals (CI. Results A total of 89 relevant studies were identified. The review found evidence for 18 co-morbidities which met the inclusion criteria. The meta-analysis determined statistically significant associations for overweight with the incidence of type II diabetes, all cancers except esophageal (female, pancreatic and prostate cancer, all cardiovascular diseases (except congestive heart failure, asthma, gallbladder disease, osteoarthritis and chronic back pain. We noted the strongest association between overweight defined by body mass index (BMI and the incidence of type II diabetes in females (RR = 3.92 (95% CI: 3.10–4.97. Statistically significant associations with obesity were found with the incidence of type II diabetes, all cancers except esophageal and prostate cancer, all cardiovascular diseases, asthma, gallbladder disease, osteoarthritis and chronic back pain. Obesity defined by BMI was also most strongly associated with the incidence of type II diabetes in females (12.41 (9.03–17.06. Conclusion Both overweight and obesity are associated with the incidence of multiple co-morbidities including type II diabetes

  8. Leptin and leptin receptor genes in relation to premenopausal breast cancer incidence and grade in Caucasian women

    OpenAIRE

    Gu, Fangyi; Kraft, Peter; Rice, Megan; Michels, Karin B

    2011-01-01

    Body mass is inversely related to breast cancer risk among premenopausal women. Leptin, an essential cytokine regulating food intake, energy expenditure, glucose, and fat metabolism may be part of the mechanistic pathway. We investigated 50 tagging and candidate SNPs in the leptin (LEP) and leptin receptor (LEPR) genes for associations with premenopausal breast cancer incidence using 405 cases and 810 controls nested within the Nurses’ Health Study II. We also examined associations between th...

  9. Incidence and risk of work-related fracture injuries: experience of a state-managed workers' compensation system.

    Science.gov (United States)

    Islam, S S; Biswas, R S; Nambiar, A M; Syamlal, G; Velilla, A M; Ducatman, A M; Doyle, E J

    2001-02-01

    Incidence rates of occupational fractures at various anatomic sites and associated risk factors have not been well documented. We identified 3490 work-related fractures from a West Virginia Workers Compensation database that occurred between July 1, 1994, and June 30, 1995. The annual incidence rate was 55 per 10,000 workers, which is substantially higher than the work-related fracture rates reported previously. The incidence rate of fracture was highest in the agricultural sector, followed by the mining, construction, and manufacturing sectors (202.0, 165.2, 116.7, and 88.0 per 10,000 workers, respectively). The age-specific gender distribution comparing fracture and non-fracture injuries showed a bimodal distribution, with greater proportions of female employees at the younger and older age groups. Fracture of the phalanges was the most common, followed by fractures of the foot bone and carpal bone (15.8, 9.5, and 7.9 per 10,000 workers, respectively). In a multiple logistic regression analysis, age, gender, occupation, caught in-between objects, fall, struck by or against object, and vehicle collision were significant independent predictors of fracture (all sites combined). We believe work-related fractures to be a bigger problem than previously reported. The association among gender, age, occupation, and causes of fractures identified in this study will be useful in developing gender- and occupation-specific prevention intervention.

  10. Incidence and risk of work-related fracture injuries: experience of a state-managed workers' compensation system.

    Science.gov (United States)

    Islam, S S; Biswas, R S; Nambiar, A M; Syamlal, G; Velilla, A M; Ducatman, A M; Doyle, E J

    2001-02-01

    Incidence rates of occupational fractures at various anatomic sites and associated risk factors have not been well documented. We identified 3490 work-related fractures from a West Virginia Workers Compensation database that occurred between July 1, 1994, and June 30, 1995. The annual incidence rate was 55 per 10,000 workers, which is substantially higher than the work-related fracture rates reported previously. The incidence rate of fracture was highest in the agricultural sector, followed by the mining, construction, and manufacturing sectors (202.0, 165.2, 116.7, and 88.0 per 10,000 workers, respectively). The age-specific gender distribution comparing fracture and non-fracture injuries showed a bimodal distribution, with greater proportions of female employees at the younger and older age groups. Fracture of the phalanges was the most common, followed by fractures of the foot bone and carpal bone (15.8, 9.5, and 7.9 per 10,000 workers, respectively). In a multiple logistic regression analysis, age, gender, occupation, caught in-between objects, fall, struck by or against object, and vehicle collision were significant independent predictors of fracture (all sites combined). We believe work-related fractures to be a bigger problem than previously reported. The association among gender, age, occupation, and causes of fractures identified in this study will be useful in developing gender- and occupation-specific prevention intervention. PMID:11227632

  11. Incidence and mortality rates of selected infection-related cancers in Puerto Rico and in the United States

    Directory of Open Access Journals (Sweden)

    Romero Carlos J

    2010-05-01

    Full Text Available Abstract Background In 2002, 17.8% of the global cancer burden was attributable to infections. This study assessed the age-standardized incidence and mortality rates of stomach, liver, and cervical cancer in Puerto Rico (PR for the period 1992-2003 and compared them to those of Hispanics (USH, non-Hispanic Whites (NHW, and non-Hispanic Blacks (NHB in the United States (US. Methods Age-standardized rates [ASR(World] were calculated based on cancer incidence and mortality data from the PR Cancer Central Registry and SEER, using the direct method and the world population as the standard. Annual percent changes (APC were calculated using the Poisson regression model from 1992-2003. Results The incidence and mortality rates from stomach, liver and cervical cancer were lower in NHW than PR; with the exception of mortality from cervical cancer which was similar in both populations. Meanwhile, the incidence rates of stomach, liver and cervical cancers were similar between NHB and PR; except for NHB women who had a lower incidence rate of liver cancer than women in PR. NHB had a lower mortality from liver cancer than persons in PR, and similar mortality from stomach cancer. Conclusions The burden of liver, stomach, and cervical cancer in PR compares to that of USH and NHB and continues to be a public health priority. Public health efforts are necessary to further decrease the burden of cancers associated to infections in these groups, the largest minority population groups in the US. Future studies need to identify factors that may prevent infections with cancer-related agents in these populations. Strategies to increase the use of preventive strategies, such as vaccination and screening, among minority populations should also be developed.

  12. Non-Alcoholic Fatty Liver Disease Is not Related to the Incidence of Diabetic Nephropathy in Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    Chun-Shan Bi

    2012-11-01

    Full Text Available To analyze the association between non-alcoholic fatty liver disease (NAFLD and the incidence of diabetic nephropathy in patients with type 2 diabetes, the incidence of diabetic nephropathy was assessed in 413 type 2 diabetic patients, by testing the 24 h urinary albumin excretion rate (UAER. The NAFLD was diagnosed based on patient’s medical history and liver ultrasound. The difference in diabetic nephropathy incidence between patients with and without NAFLD was tested by χ2. Multivariate logistic regression analysis was used to assess the factors associated with diabetic nephropathy among type 2 diabetic patients. Total 363 out of 413 type 2 diabetic patients were enrolled in this study. The incidences of NAFLD and diabetic nephropathy in participants were approximately 56% (202/363 and 38% (137/363 respectively, and there was no significant difference in the prevalence of diabetic nephropathy between patients with and without NAFLD (37.1% vs. 38.5%, p = 0.787. The duration of diabetes (odds ratio [OR] 1.065, 95% confidence interval [CI] 1.014–1.120, p = 0.012, waist circumference (OR 1.077, 95% CI 1.040–1.116, p = 0.000, and fasting blood glucose (FBG; OR 1.136, 95% CI 1.023–1.1262, p = 0.017 were significantly associated with diabetic nephropathy, whereas sex, high blood pressure, total cholesterol (TC, triglyceride (TG, and ankle brachial pressure index (ABI were not significantly associated with the disorder. The present results suggest that NAFLD is not related to the incidence of diabetic nephropathy in type 2 diabetes, but the duration of diabetes, waist circumference, and FBG are important factors for diabetic nephropathy in type 2 diabetes.

  13. Incidence and Related Factors Associated with Postpreparation Pain after Intracanal Procedures in a Dental Teaching Hospital

    Institute of Scientific and Technical Information of China (English)

    Yue Cheng; Gary Shun-Pan Cheung; Zhuan Bian; Bin Peng

    2008-01-01

    目的:了解根管预备后疼痛发生率,并对一些可能与疼痛发生有关的因素进行分析.方法:选取2001年7月至2002年2月间武汉大学口腔医院牙体牙髓科完成的非一次法根管治疗纪录表,将相关信息输入计算机后作Chi-square test和logistic回归分析.结果:根管预备后疼痛发生率为11.5%.单因素分析和logistic回归发现身体状况、年龄、牙位于上颌或下颌、术前有无叩痛及牙髓活力为影响疼痛发生率的主要因素.结论:根管预备术后疼痛发生率较低;根管预备术后疼痛发生率受多种因素影响.%Objective:To investigate the incidence of postpreparation pain during root canal therapy(RCT)in a dental teaching hospital and to evaluate the factors affecting the pain experience.Methods:A total of 3512 cases were collected at RCT appointments on demographics,presenting symptoms,treatment procedures and periradicular status.Root canals were conventional instrumented and then medicated.The presence and severity of postpreparation pain after a subsequent endodontic treatment was recorded.The data of postpreparation pain cases were statistically analyzed using the Chi-square test and a multiple logistic regression model.Results:The incidence of postpreparation pain was 11.5%.Analyses of all potential factom revealed that patient age,health status,tooth location,pre-operative percussion pain and pulp status were the factors to significantly influence postpreparation pain experience.Conclusion:The prevalence of postpreparation pain Was low and significantly influenced by multiple factors.

  14. Work-related critical incidents in hospital-based health care providers and the risk of post-traumatic stress symptoms, anxiety, and depression: A meta-analysis

    NARCIS (Netherlands)

    J.C. Boer; A. Lok; E. van't Verlaat; H.J. Duivenvoorden; A.B. Bakker; B.J. Smit

    2011-01-01

    This meta-analysis reviewed existing data on the impact of work-related critical incidents in hospital-based health care professionals. Work-related critical incidents may induce post-traumatic stress symptoms or even post-traumatic stress disorder (FTSD), anxiety, and depression and may negatively

  15. Red cell distribution width in relation to incidence of stroke and carotid atherosclerosis: a population-based cohort study.

    Directory of Open Access Journals (Sweden)

    Martin Söderholm

    Full Text Available Increased red cell distribution width (RDW has been related to poor prognosis in patients with cardiovascular disease, and is a predictor of cardiovascular mortality in the general population. The purpose of the present study was to investigate if RDW is associated with increased incidence of stroke and its subtypes in individuals from the general population.Red cell distribution width was measured in 26,879 participants (16,561 women and 10,318 men aged 45-73 years without history of coronary events or stroke, from the population-based Malmö Diet and Cancer Study. Incidences of total stroke and stroke subtypes over a mean follow-up of 15.2 years were calculated in relation to sex-specific quartiles of RDW. The presence of carotid plaque and intima-media thickness, as assessed by ultrasound, was studied in relation to RDW in a randomly selected subcohort (n = 5,309.Incidences of total stroke (n = 1,869 and cerebral infarction (n = 1,544 were both increased in individuals with high RDW. Hazard ratios (HRs in the highest compared to the lowest quartile were 1.31 for total stroke (95% confidence interval [CI]: 1.11-1.54, p for trend = 0.004 and 1.32 for cerebral infarction (95% CI: 1.10-1.58, p for trend = 0.004 after adjustment for stroke risk factors and hematological parameters. The adjusted HR for intracerebral hemorrhage (n = 230 was 1.44 (95% CI: 0.90-2.30 and the HR for subarachnoid hemorrhage (n = 75 was 0.94 (95% CI: 0.43-2.07, in the highest compared to the lowest quartile of RDW. Red cell distribution width was positively associated with intima-media thickness of the common carotid artery (p for trend = 0.011.Red cell distribution width in the highest quartile was associated with increased incidence of total stroke and cerebral infarction. There was no significant association between RDW and incidence of intracerebral or subarachnoid hemorrhage.

  16. Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study

    Science.gov (United States)

    Weisskopf, Marc G.; Sparrow, David; Schwartz, Joel; Hu, Howard; Park, Sung Kyun

    2016-01-01

    Background Cumulative exposure to lead is associated with cardiovascular outcomes. Polymorphisms in the δ-aminolevulinic acid dehydratase (ALAD), hemochromatosis (HFE), heme oxygenase-1 (HMOX1), vitamin D receptor (VDR), glutathione S-transferase (GST) supergene family (GSTP1, GSTT1, GSTM1), apolipoprotein E (APOE),angiotensin II receptor-1 (AGTR1) and angiotensinogen (AGT) genes, are believed to alter toxicokinetics and/or toxicodynamics of lead. Objectives We assessed possible effect modification by genetic polymorphisms in ALAD, HFE, HMOX1, VDR, GSTP1, GSTT1, GSTM1, APOE, AGTR1 and AGT individually and as the genetic risk score (GRS) on the association between cumulative lead exposure and incident coronary heart disease (CHD) events. Methods We used K-shell-X-ray fluorescence to measure bone lead levels. GRS was calculated on the basis of 22 lead-related loci. We constructed Cox proportional hazard models to compute adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for incident CHD. We applied inverse probability weighting to account for potential selection bias due to recruitment into the bone lead sub-study. Results Significant effect modification was found by VDR, HMOX1, GSTP1, APOE, and AGT genetic polymorphisms when evaluated individually. Further, the bone lead-CHD associations became larger as GRS increases. After adjusting for potential confounders, a HR of CHD was 2.27 (95%CI: 1.50–3.42) with 2-fold increase in patella lead levels, among participants in the top tertile of GRS. We also detected an increasing trend in HRs across tertiles of GRS (p-trend = 0.0063). Conclusions Our findings suggest that lead-related loci as a whole may play an important role in susceptibility to lead-related CHD risk. These findings need to be validated in a separate cohort containing bone lead, lead-related genetic loci and incident CHD data. PMID:27584680

  17. Incidence of rhinitis and asthma related to welding in Northern Europe.

    NARCIS (Netherlands)

    Storaas, T.; Zock, J.P.; Morano, A.E; Holm, M.; Bjornsson, E.; Forsberg, B.; Janson, C.; Norbäck, D.; Omenass, E.; Schlünssen, V.; Torén, K.; Svanes, C.

    2015-01-01

    Welding-related asthma is well recognised but less is known about rhinitis in relation to welding. The aim here, was to study associations between welding, rhinitis and asthma in a general population sample, and factors influencing selection into and out of a welding occupation. Adult-onset asthma

  18. Negative aspects of close social relations and 10-year incident ischaemic heart disease hospitalization among middle-aged Danes

    DEFF Research Database (Denmark)

    Lund, Rikke; Rod, Naja Hulvej; Thielen, Karsten;

    2014-01-01

    was found for conflicts with partner. High levels of worries/demands from or conflicts with family and friends were associated with a 40% higher risk of IHD. CONCLUSIONS: Negative aspects of close social relations are associated with higher risk of incident IHD hospitalization except for conflicts......BACKGROUND: Little is known about the association between negative aspects of close social relations and development of ischaemic heart disease (IHD). We aim to address if the experience of worries/demands and conflicts with close social relations are related to risk of first-time hospitalization...... National Patient Registry. Cox regression analysis was used to analyse data and all analyses were adjusted for age, gender, social class, cohabitation, and depressive symptoms. RESULTS: Worries/demands from and conflicts with children were associated with IHD hospitalization in an exposure-dependent manner...

  19. Water incident related hospital activity across England between 1997/8 and 2003/4: a retrospective descriptive study

    Directory of Open Access Journals (Sweden)

    Wilson Richard C

    2006-08-01

    Full Text Available Abstract Background No one has ever reported or investigated the number of people who have been admitted to hospital for a water related incident. The purpose of this paper is to examine, the hospital activity resulting from such incidents including to length of stay, gender, age and cause. Methods The data was extracted from the Hospital Episode Statistics (HES for episodes with a mention of ICD 10 (V90–94, W15–16, W65–74, X38, X92, Y21 for the years 1997/8 to 2003/4. Population based rates and relative risk were calculated using the most recent Census data for England (2001. Results The 6,793 episodes resulted in a total of 32,520 bed days with an average of length of stay of 5.0 days. Males made up 73.7% (n = 5,006 of episodes and females 26.1% (n = 1,787. Annual trends peaked in 1999–2000 at a rate of 2.4 per 100,000 and have fluctuated on alternate years there after. In terms of relative risk males are at a 2.3 to 3.0 increased annual risk of being admitted compared to females, relating to a water event. The highest annual rates were observed within the 0 – 14 age group, ranging from 3.1 to 4.2 episodes per 100,000. Conclusion Based on these findings, for every one drowning that occurs per year there are three hospital episodes. Each of the age groups identified within the study reported an increase in hospital episodes between 2002 – 2003 and 2003 – 2004, when considering the fatality information available it would appear that although fatalities are decreasing in the similar time period, hospital episodes are increasing. For the 0–14 age group, the cause of the injury had changed over the years, moving away from bath tub and swimming pool, to watercraft incidents (V91 – 93. For the 15 – 59 age group there had been a decline in the frequency of watercraft and water transport episodes, however, an increase in diving and jumping injury and incidents. In the over 60 age group water transport episodes remained the most

  20. Incidence, severity and management of cancer chemotherapy related oral mucositis in Eastern Cape and Western Cape

    Directory of Open Access Journals (Sweden)

    Johanna E. Maree

    2012-10-01

    Full Text Available This study explored the incidence, duration and severity of oral mucositis in patients receiving chemotherapy in the Eastern and Western Cape, how this symptom was managed and whether the patients considered the management to be effective. An exploratory, contextual, quantitative survey was conducted. The sampling method was convenience. One hundred and sixty patients were recruited, with 106, (66.3% participating. Data were collected by means of self-reports, using a self-administered questionnaire. Oral mucositis was a common problem, with 71.7% (n = 76 reporting to have had mucositis. Pain was not effectively managed, as 69.8% (n = 53 of respondents experienced pain whilst only 17.1% (n = 13 reported to have used analgesics. More than half of the respondents used prescribed mouth and throat preparations, whilst 28.9% (n = 22 used non-prescribed self-care measures including potentially harmful products. A significant difference was found between using non-prescribed self-care measures and the duration of oral mucositis (χ² = 0.81; p = 0.01. The reported grade of mucositis did not influence the use of non-prescribed self-care measures, whilst the more pain patients experienced the less inclined they were to use these measures. The management of oral mucositis remains a challenge. Failure to palliate this distressing symptom can lead to the use of potentially harmful self-care measures. Die studie het die insidensie, tydsduur en intensiteit van orale mukositis in Oos en Wes Kaapse pasiënte wat kankerchemoterapie ontvang verken asook hoe hierdie simptoom hanteer is en die sukses hiervan volgens die pasiënte. ‘n Kwantitatiewe, ekploratiewe, kontekstuele opname is onderneem. ‘n Gerieflikheidsteekproef is gebruik om die deelnemers te verkry. Een hondered en sestig persone is genader en 66.3% (n = 106 het aan die studie deelgeneem. Die datainsamelingsmetode was self-rapportering met behulp van ’n vraelys en beskrywende statistiek is gebruik

  1. Meta-Analysis of Oral Implant Fracture Incidence and Related Determinants

    OpenAIRE

    Pommer, Bernhard; Bucur, Lavinia; Zauza, Konstantin; Tepper, Gabor; Hof, Markus; Watzek, Georg

    2014-01-01

    Dental implant fracture is a rare biomechanical complication, however, one of the most serious and frustating ones as it is generally associated with implant and prosthesis failure as well as the surgical hazards of explantation and reimplantation. To gain insights into implant fracture rates and the impact of patient-, surgery-, and prosthetic-related factors, systematic review and meta-analysis of the English literature were performed. Electronic and hand searches yielded 69 relevant public...

  2. The reported incidence of work-related musculoskeletal disease in the UK: MOSS 1997-2000.

    Science.gov (United States)

    Cherry, N M; Meyer, J D; Chen, Y; Holt, D L; McDonald, J C

    2001-10-01

    Consultant rheumatologists participate in surveillance of work-related musculoskeletal conditions under the Musculoskeletal Occupational Surveillance Scheme (MOSS), which has been in operation since 1997. During the first 3 years of the scheme, an estimated total of 8070 cases and 8442 diagnoses were obtained, an average of slightly less than 2700 estimated cases each year. Disorders of the upper limb accounted for approximately 66% (5502) of the total, with hand/wrist/arm conditions (3693 cases) comprising the majority of these. Conditions of the lumbar spine and trunk (13% of cases), the cervical spine (12%) and the shoulder (12%) were also frequently reported. Pain with ill-defined pathology was reported in 35% of cases with hand and forearm disorders. Overall, 82% of cases were related to repetitive rather than single injury. The largest numbers of cases were seen in workers in craft occupations (1659) and in clerical and secretarial workers (1524). High rates of musculoskeletal conditions, particularly of upper limb disorders, are notable in mining. In most occupations, and overall, women were at greater risk than men.

  3. Relative incidence of Bactrocera cucurbitae (Coquillett) and Dacus ciliatus Loew on cucurbitaceous vegetables

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, N.K. Krishna; Verghese, Abraham; Shivakumara, B.; Krishnamoorthy, P.N.; Ranganath, H.R. [Indian Institute of Horticultural Research, Bangalore (India). Div. of Entomology and Nematology

    2006-07-01

    The melon fly, Bactrocera cucurbitae (Coquillett) is a major pest of cucurbitaceous vegetables and fruits in many parts of the world. Infestation of an another species, the lesser pumpkin fly, Dacus ciliatus Loew is reported on a few cucurbits in the Indian sub-continent and Africa. While extensive work on seasonality, infestation percent, host preference, attraction to para pheromone on B. cucurbitae has been reported, little is known of D. ciliatus. Field experiments were carried out at the Indian Institute of Horticultural Research (IIHR), Bangalore (12058'N; 77035'E) from June 2002- October 2003. Cucumber (Cucumis sativus L), ridge gourd (Luffa acutangula (L.) Roxb), bitter gourd (Momordica charantia L.) and pickling cucumbers [C. sativus L (variety. Ijax)] were raised at monthly interval. Cue lure baited bottle traps were hung to monitor B. cucurbitae and other related species. Bactrocera cucurbitae was present all through the year and maximum number of adults was trapped during August (14.14/trap/week). Dacus ciliatus was trapped only from May to October but in relatively less numbers ({approx} 1/week). Maximum fruit fly infestation was 77.03 % on bitter gourd (August 2003), 75.65 % on ridge gourd (Nov. 02), 73.83 % on cucumber (October, 02) and 63.31 % on pickling cucumber (October, 02). Trap catches of B. cucurbitae was significantly and positively correlated with relative humidity. Maximum and minimum temperature, RH (%), rainfall (mm), evaporation (mm) and wind speed (km/h) collectively determined 44 % of B. cucurbitae trap catches. Maximum fruit fly emergence of 494.64/ kg fruit was on bitter gourd (October, 2002) followed by cucumber (431.97, November, 2002), pickling cucumber (307.51, October 2002) and ridge gourd (210.74, October, 2003). Dacus ciliatus formed only 4.5% of the total number of fruit flies on bitter gourd and 0.2% on pickling cucumber. Its infestation was not observed on cucumber and ridge gourd. Parasitism by the larval

  4. What Works to Overcome Indigenous Disadvantage: Key Learnings and Gaps in the Evidence. Closing the Gap Clearinghouse. 2009-10

    Science.gov (United States)

    Al-Yaman, Fadwa; Higgins, Daryl

    2011-01-01

    The Closing the Gap Clearinghouse was established by the Council of Australian Governments (COAG) to bring together evidence-based research on overcoming disadvantage for Indigenous Australians. The Clearinghouse provides access to a collection of information on what works to improve Indigenous people's lives across the building blocks identified…

  5. Breast cancer incidence and mortality in the Nordic capitals, 1970-1998. Trends related to mammography screening programmes

    Energy Technology Data Exchange (ETDEWEB)

    Toernberg, Sven; Kemetli, Levent [Karolinska Univ. Hospital, Stockholm (Sweden). Cancer Screening Unit, Oncologic Centre; Lynge, Elsebeth; Olsen, Anne Helene [Univ. of Copenhagen, (Denmark). Inst. of Public Health; Hofvind, Solveig; Wang, Hege [The Cancer Registry of Norway, Oslo (Norway); Anttila, Ahti [Finnish Cancer Registry, Helsinki (Finland); Hakama, Matti [Univ. of Tampere (Finland). School of Public Health; Nystroem, Lennarth [Umeaa Univ. (Sweden). Dept. of Public Health and Clinical Medicine

    2006-07-15

    The aim of the present study was to relate the time trends in breast cancer incidence and mortality to the introduction of mammography screening in the Nordic capitals. Helsinki offered screening to women aged 50-59 starting in 1986. The other three capitals offered screening to women aged 50-69 starting in 1989 in Stockholm, 1991 in Copenhagen, and 1996 in Oslo. Prevalence peaks in breast cancer incidence depended on the age groups covered by the screening, the length of the implementation of screening, and the extent of background opportunistic screening. No mortality reduction following the introduction of screening was visible after seven to 12 years of screening in any of the three capitals where significant effects of the screening on the breast cancer mortality had already been demonstrated by using other analytical methods for the evaluation. No visible effect on mortality reduction was expected in Oslo due to too short an observation period. The study showed that the population-based breast cancer mortality trend is too crude a measure to detect the effect of screening on breast cancer mortality during the first years after the start of a programme.

  6. Leptin and leptin receptor genes in relation to premenopausal breast cancer incidence and grade in Caucasian women.

    Science.gov (United States)

    Gu, Fangyi; Kraft, Peter; Rice, Megan; Michels, Karin B

    2012-01-01

    Body mass is inversely related to breast cancer risk among premenopausal women. Leptin, an essential cytokine regulating food intake, energy expenditure, glucose, and fat metabolism may be part of the mechanistic pathway. We investigated 50 tagging and candidate SNPs in the leptin (LEP) and leptin receptor (LEPR) genes for associations with premenopausal breast cancer incidence using 405 cases and 810 controls nested within the Nurses' Health Study II. We also examined associations between these SNPs and circulating leptin (among 910 women) and breast cancer grade (among 267 patients). Permutation tests were performed to adjust for multiple testing. We did not detect a significant association between SNPs in the LEP or LEPR gene and either breast cancer incidence or plasma leptin levels. Among cases, 14 SNPs of the LEPR gene were significantly associated with cancer grade, and rs1137101 (Q223R) survived multiple testing adjustment (adjusted P = 0.04). The G carriers of rs1137101 were more likely to have poorly differentiated than well-differentiated cancers. Our data suggest that common genetic variation in the LEP or LEPR gene has no strong association with premenopausal breast cancer risk. The LEPR gene might be associated with breast cancer grade. PMID:21947707

  7. Reflectance spectroscopy: a tool for predicting soil properties related to the incidence of Fe chlorosis

    Energy Technology Data Exchange (ETDEWEB)

    Canasveras, J. C.; Barron, V.; Campillo, M. C. del; Viscarra Rossel, R. A.

    2012-07-01

    Chlorosis due to iron (Fe) deficiency (internervial yellowing) is the most important nutritional problem a susceptible plant can have in calcareous soils. Fe chlorosis is related with calcium carbonate equivalent (CCE), clay content and Fe extracted with oxalate (Fe{sub o}). Reflectance spectroscopy (RS) is a rapid, non-destructive, less expensive alternative tool that can be used to enhance or replace conventional methods of soil analysis. The aim of this work was to assess the usefulness of RS for the determination of some properties of Mediterranean soils including clay content, CCE, Feo, cation exchange capacity (CEC), organic matter (OM) and pH in water (pH{sub w}), with emphasis on those with a specially marked influence on the risk of Fe chlorosis. To this end, we used partial least-squares regression (PLS) to construct calibration models, leave-one-out cross-validation and an independent validation set. Our results testify to the usefulness of qualitative soil interpretations based on the variable importance for projection (VIP) as derived by PLS decomposition. The accuracy of predictions in each of the Vis-NIR, MIR and combined spectral regions differed considerably between properties. The R{sup 2}{sub a}dj and root mean square error (RMSE) for the external validation predictions were as follows: 0.83 and 37 mg kg{sup -}1 for clay content in the Vis-NIR-MIR range; 0.99 and 25 mg kg{sup -}1 for CCE, 0.80 and 0.1 mg kg{sup -}1 for Feo in the MIR range; 0.93 and 3 cmolc kg{sup -}1 for CEC in the Vis-NIR range; 0.87 and 2 mg kg{sup -}1 for OM in the Vis-NIR-MIR range, 0.61 and 0.2 for pH{sub w} in the MIR range. These results testify to the potential of RS in the Vis, NIR and MIR ranges for efficient soil analysis, the acquisition of soil information and the assessment of the risk of Fe chlorosis in soils. (Author) 36 refs.

  8. Anthropogenic impacts to the recovery of the Mexican gray wolf with a focus on trapping-related incidents

    Science.gov (United States)

    Turnbull, Trey T.; Cain, James W.; Roemer, Gary W.

    2013-01-01

    Concerns regarding the potential negative impacts of regulated furbearer trapping to reintroduced Mexican gray wolves (Canis lupus baileyi), led to an executive order prohibiting trapping in the New Mexico, USA, portion of the Blue Range Wolf Recovery Area. This ban was to last for 6 months and required an evaluation of the risk posed to wolves by traps and snares legally permitted in New Mexico. We reviewed potential threats to wolves in the Blue Range Wolf Recovery Area, including threats associated with regulated furbearer trapping. One hundred Mexican gray wolf mortalities have been documented during the reintroduction effort (1998–2011). Of those mortalities with a known cause, >81% were human-caused resulting from illegal shooting (n = 43), vehicle collisions (n = 14), lethal removal by the United States Fish and Wildlife Service (USFWS; n = 12), non-project-related trapping (n = 2), project-related trapping (n = 1), and legal shooting by the public (n = 1). Ten wolves died due to unknown causes. The remaining 17 mortalities were a result of natural causes (e.g., starvation, disease). An additional 23 wolves were permanently, but non-lethally, removed from the wild by the USFWS. Of 13 trapping incidents in New Mexico that involved non-project trappers (i.e., trappers not associated with USFWS or U.S. Department of Agriculture-Wildlife Services), 7 incidents are known to have resulted in injuries to wolves: 2 wolves sustained injuries severe enough to result in leg amputations and 2 additional wolves died as a result of injuries sustained. Foothold traps with rubber-padded jaws and properly set snares may reduce trap-related injuries to Mexican gray wolves; however, impacts caused by trapping are overshadowed by other anthropogenic impacts (e.g., illegal shooting, non-lethal permanent removal, and vehicle collisions).

  9. Incidence of lesions on Fungiidae corals in the eastern Red Sea is related to water temperature and coastal pollution

    KAUST Repository

    Furby, K.A.

    2014-07-01

    As sea surface temperatures rise and the global human population increases, large-scale field observations of marine organism health and water quality are increasingly necessary. We investigated the health of corals from the family Fungiidae using visual observations in relation to water quality and microbial biogeochemistry parameters along 1300 km of the Red Sea coast of Saudi Arabia. At large scales, incidence of lesions caused by unidentified etiology showed consistent signs, increasing significantly from the northern to southern coast and positively correlated to annual mean seawater temperatures. Lesion abundance also increased to a maximum of 96% near the populous city of Jeddah. The presence of lesioned corals in the region surrounding Jeddah was strongly correlated with elevated concentrations of ammonium and changes in microbial communities that are linked to decreased water quality. This study suggests that both high seawater temperatures and nutrient pollution may play an indirect role in the formation of lesions on corals. © 2014 Elsevier Ltd.

  10. Guide and example plan for development of state emergency response plans and systems for transportation: related radiation incidents

    International Nuclear Information System (INIS)

    As a part of their responsibilities for control of radiation sources and for minimizing unwarranted human exposures to radiation, State radiation control agencies (also referred to as radiological health agencies in some States) have developed or are in the process of developing plans and procedures for coping with emergency situations which may arise from the use, transport, or disposal of radioactive materials and other radiation sources. This guide and example plan has been prepared as an aid to radiation control agencies, emergency services organizations, and other public institutions which may have primary or supportive roles in radiation emergency response planning. This document focuses on planning, training, and emergency action procedures for such organizations and is directed toward transportation-related radiation incidents

  11. An analysis of the incidence and related factors for radiation dermatitis in breast cancer patients who receive radiation therapy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sun Young; Kwon, Hyoung Cheol; Kim, Jung Soo [Dept. of Radiation Oncology, Chonbuk National University Hospital, Jeonju (Korea, Republic of); Lee, Heui Kwan [Prebyterian Medical Center, Jeonju (Korea, Republic of)

    2010-11-15

    We analyzed the incidence and related factors of radiation dermatitis; at first, to recognize whether a decrease in radiation dermatitis is possible or not in breast cancer patients who received radiation therapy. Of 338 patients, 284 with invasive breast cancer who received breast conservation surgery with radiotherapy at Chonbuk National University Hospital from January 2007 to June 2009 were evaluated. Patients who also underwent bolus, previous contralateral breast irradiation and irradiation on both breasts were excluded. For patients who appeared to have greater than moderate radiation dermatitis, the incidence and relating factors for radiation dermatitis were analyzed retrospectively. A total of 207 and 77 patients appeared to have RTOG grade 0/1 or above RTOG grade 2 radiation dermatitis, respectively. The factors found to be statistically significant for the 77 patients who appeared to have greater than moderate radiation dermatitis include the presence of lymphocele due to the stasis of lymph and lymph edema which affect the healing disturbance of radiation dermatitis (p=0.003, p=0.001). Moreover, an allergic reaction to plaster due to the immune cells of skin and the activation of cytokine and concomitant hormonal therapy were also statistically significant factors (p=0.001, p=0.025). Most of the breast cancer patients who received radiation therapy appeared to have a greater than mild case of radiation dermatitis. Lymphocele, lymphedema, an allergy to plaster and concomitant hormonal therapy which affect radiation dermatitis were found to be significant factors. Consequently, we should eliminate lymphocele prior to radiation treatment for patients who appear to have an allergic reaction to plaster. We should also instruct patients of methods to maintain skin moisture if they appear to have a greater than moderate case of radiation dermatitis.

  12. The Pennsylvania Experience with Hydraulic Fracturing for Shale Gas Development: Relatively Infrequent Water Quality Incidents with Lots of Public Attention

    Science.gov (United States)

    Brantley, S. L.; Li, Z.; Yoxtheimer, D.; Vidic, R.

    2015-12-01

    New techniques of hydraulic fracturing - "fracking" - have changed the United States over the last 10 years into a leading producer of natural gas extraction from shale. The first such gas well in Pennsylvania was drilled and completed using high-volume hydraulic fracturing in 2004. By late 2014, more than 8500 of these gas wells had been drilled in the Marcellus Shale gas field in Pennsylvania alone. Almost 1000 public complaints about groundwater quality were logged by the PA Department of Environmental Protection (PA DEP) between 2008 and 2012. Only a fraction of these were attributed to unconventional gas development. The most common problem was gas migration into drinking water, but contamination incidents also included spills, seepage, or leaks of fracking fluids, brine salts, or very occasionally, radioactive species. Many problems of gas migration were from a few counties in the northeastern part of the state. However, sometimes one gas well contaminated multiple water wells. For example, one gas well was reported by the state regulator to have contaminated 18 water wells with methane near Dimock PA. It can be argued that such problems at a relatively small fraction of gas wells initiated pockets of pushback against fracking worldwide. This resistance to fracking has grown even though fracking has been in use in the U.S.A. since the 1940s. We have worked as part of an NSF-funded project (the Shale Network) to share water quality data and publish it online using the CUAHSI Hydrologic Information System. Sharing data has led to collaborative investigation of specific contamination incidents to understand how problems can occur, and to efforts to quantify the frequency of impacts. The Shale Network efforts have also highlighted the need for more transparency with water quality data in the arena related to the energy-water nexus. As more data are released, new techniques of data analysis will allow better understanding of how to tune best practices to be

  13. An analysis of the incidence and related factors for radiation dermatitis in breast cancer patients who receive radiation therapy

    International Nuclear Information System (INIS)

    We analyzed the incidence and related factors of radiation dermatitis; at first, to recognize whether a decrease in radiation dermatitis is possible or not in breast cancer patients who received radiation therapy. Of 338 patients, 284 with invasive breast cancer who received breast conservation surgery with radiotherapy at Chonbuk National University Hospital from January 2007 to June 2009 were evaluated. Patients who also underwent bolus, previous contralateral breast irradiation and irradiation on both breasts were excluded. For patients who appeared to have greater than moderate radiation dermatitis, the incidence and relating factors for radiation dermatitis were analyzed retrospectively. A total of 207 and 77 patients appeared to have RTOG grade 0/1 or above RTOG grade 2 radiation dermatitis, respectively. The factors found to be statistically significant for the 77 patients who appeared to have greater than moderate radiation dermatitis include the presence of lymphocele due to the stasis of lymph and lymph edema which affect the healing disturbance of radiation dermatitis (p=0.003, p=0.001). Moreover, an allergic reaction to plaster due to the immune cells of skin and the activation of cytokine and concomitant hormonal therapy were also statistically significant factors (p=0.001, p=0.025). Most of the breast cancer patients who received radiation therapy appeared to have a greater than mild case of radiation dermatitis. Lymphocele, lymphedema, an allergy to plaster and concomitant hormonal therapy which affect radiation dermatitis were found to be significant factors. Consequently, we should eliminate lymphocele prior to radiation treatment for patients who appear to have an allergic reaction to plaster. We should also instruct patients of methods to maintain skin moisture if they appear to have a greater than moderate case of radiation dermatitis.

  14. Further development of acquisition and evaluation of notifiable incidents and other registrated events during the operation of nuclear power plants, related to human failure

    International Nuclear Information System (INIS)

    The project SR 2039/1 aims at further developing the existing reporting system designed to register and evaluate incidents and other events in order to enable a proper incorporation of human factor related incidents. Another objective consists in suggesting techniques and methods to include HF aspects in the acquisition and evaluation of incidents below the reporting threshold. Since the acquisition and evaluation of such incidents is the duty of the operator, the development of efficient methods is supported. Naturally, the Federal Office for Radiation Protection (BfS) and the Federal Ministry for the Environment, Nature Conservation and Reactor Safety (BMU) have a legitimate interest in making sure of the efficiency of registration and evaluation of such incidents for which operators are directly responsible. Therefore, a survey concept is suggested which helps to accomplish this task. (orig./DG)

  15. Incidence and risk factors of bleeding-related adverse events in patients with chronic lymphocytic leukemia treated with ibrutinib

    DEFF Research Database (Denmark)

    Lipsky, Andrew H; Farooqui, Mohammed Z H; Tian, Xin;

    2015-01-01

    Ibrutinib is associated with bleeding-related adverse events of grade ≤2 in severity, and infrequently with grade ≥3 events. To investigate the mechanisms of bleeding and identify patients at risk, we prospectively assessed platelet function and coagulation factors in our investigator-initiated t......Ibrutinib is associated with bleeding-related adverse events of grade ≤2 in severity, and infrequently with grade ≥3 events. To investigate the mechanisms of bleeding and identify patients at risk, we prospectively assessed platelet function and coagulation factors in our investigator......-initiated trial of single-agent ibrutinib for chronic lymphocytic leukemia. At a median follow-up of 24 months we recorded grade ≤2 bleeding-related adverse events in 55% of 85 patients. No grade ≥3 events occurred. Median time to event was 49 days. The cumulative incidence of an event plateaued by 6 months...... 19 patients on ibrutinib (often transiently). Collagen and adenosine diphosphate induced platelet aggregation was tested using whole blood aggregometry. Compared to normal controls, response to both agonists was decreased in all patients with chronic lymphocytic leukemia, whether on ibrutinib or not...

  16. Trends in Injury-related Incidence and Mortality Among Inpatients in Guangdong Province in 1997-2001

    Institute of Scientific and Technical Information of China (English)

    LI-PING LI; SHENG WANG

    2004-01-01

    Currently, China is in short of thorough and systemic data concerning the patterns and incidence of injuries and related deaths. Guangdong Province as one of the economically advanced areas in China is faced with a relatively serious injury problem, and investigation of this problem in this Province will provide valuable information for other provinces and areas in this Country, as well as scientific basis for policy making for injury prevention and control. Methods Analyses are based on the computerized hospital discharge data collected from 322 hospitals in Guangdong Province between 1997 and 2001. Diagnoses are coded according to the International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM). Results The total hospitalization rate related with injuries increased year by year from 1997 to 2001. The ratio of case-fatality has a decline trend for all injury inpatients, who were mainly caused by motor vehicle accidents, unintentional falls, puncture and cut by machine and others. The constituent ratio of death among patients caused by motor vehicle accidents accounted for 56.13% among the total deaths, which ranked as the first place. The direct medical cost also had an increased trend. Conclusions Data on injuries requiring hospitalization can be used to design and target more effective injury prevention programs. Injury prevention would decrease human sufferings, disability, and associated economic losses.

  17. Use of the Tego needlefree connector is associated with reduced incidence of catheter-related bloodstream infections in hemodialysis patients

    Directory of Open Access Journals (Sweden)

    Brunelli SM

    2014-04-01

    Full Text Available Steven M Brunelli,1 Levi Njord,2 Abigail E Hunt,1 Scott P Sibbel1 1DaVita Clinical Research®, Minneapolis, MN, USA; 2DaVita HealthCare Partners, Inc, Denver, CO, USA Background and objectives: Catheter-related bloodstream infections (CRBSIs are common in hemodialysis patients using central venous catheters, and catheter occlusion also occurs frequently. The Tego needlefree connector was developed to reduce the incidence of these complications; however, existing studies of its effectiveness and safety are limited. Materials and methods: This retrospective analysis compared outcomes among patients of a large dialysis organization receiving in-center hemodialysis using a central venous catheter with either the Tego connector or standard catheter caps between October 1 and June 30, 2013. Incidence rates for intravenous (IV antibiotic starts, receipt of an IV antibiotic course, positive blood cultures, mortality, and missed dialysis treatments were calculated, and incidence-rate ratios (IRRs were estimated using Poisson regression models. Utilization of erythropoiesis-stimulating agents (ESAs and thrombolytics was described for each patient-month and compared using mixed linear models. Models were run without adjustment, adjusted for covariates that were imbalanced between cohorts, or fully adjusted for all potential confounders. Results: The analysis comprised 10,652 Tego patients and 6,493 controls. Tego use was independently associated with decreased risk of CRBSI, defined by initiation of IV antibiotics (adjusted IRR 0.92, 95% confidence interval [CI] 0.87–0.97 or initiation of IV antibiotic course (adjusted IRR 0.89, 95% CI 0.84–0.95. Tego use was independently associated with decreased rate of missed dialysis treatments (adjusted IRR 0.98, 95% CI 0.97–1.00; no significant difference between Tego and control cohorts was observed with respect to mortality. Tego use was associated with decreased likelihood of thrombolytic use (adjusted per

  18. A prospective study of gynecological cancer risk in relation to adiposity factors: cumulative incidence and association with plasma adipokine levels.

    Directory of Open Access Journals (Sweden)

    Meei-Maan Wu

    Full Text Available BACKGROUND: Associations of obesity and obesity-related metabolic factors (adiposity factors with uterine corpus cancer (UCC and ovarian cancer (OVC risk have been described. Still, a cause-effect relationship and the underlying mediators remain unclear, particularly for low-incidence populations. We aimed to prospectively determine whether adiposity factors could predict the development of UCC and OVC in Taiwanese women. To explore the biological mediators linking adiposity factors to cancer risk, we examined the association of two adipokines, leptin and adiponectin, with the gynecological cancers. METHODS: Totally, 11,258 women, aged 30-65, were recruited into the Community-Based Cancer Screening Program (CBCSP study during 1991-1993, and were followed for UCC and OVC cases until December 31, 2011. Cox proportional hazard models were used to estimate hazard ratios (HRs. Adiposity factors and risk covariates were assessed at recruitment. Newly-developed cancer cases were determined from data in the government's National Cancer Registry and Death Certification System. For adipokienes study, a nested case-control study was conducted within the cohort. Baseline plasma samples of 40 incident gynecological cancer cases and 240 age-menopause-matched controls were assayed for adipokines levels. FINDINGS: There were 38 and 30 incident cases of UCC and OVC, respectively, diagnosed during a median 19.9 years of follow-up. Multivariate analysis showed that alcohol intake (HR = 16.00, 95%  = 4.83-53.00, high triglyceride levels (HR = 2.58, 95% = 1.28-5.17, and years of endogenous estrogen exposure per 5-year increment (HR = 1.91, 95%  = 1.08-3.38 were associated with increased UCC risk. High body mass index (BMI ≥ 27 kg/m(2, HR = 2.90, 95%  = 1.30-6.46 was associated with increased OVC risk. Analysis further showed an independent effect of adipokines on UCC and OVC risk after adjustment of the risk covariates. CONCLUSION: We provided evidence

  19. The incidence and relative risk of stroke among patients with bipolar disorder: a seven-year follow-up study.

    Directory of Open Access Journals (Sweden)

    Hung-Chi Wu

    Full Text Available OBJECTIVE: This study aimed to estimate the incidence and relative risk of stroke and post-stroke all-cause mortality among patients with bipolar disorder. METHODS: This study identified a study population from the National Health Insurance Research Database (NHIRD between 1999 and 2003 that included 16,821 patients with bipolar disorder and 67,284 age- and sex-matched control participants without bipolar disorder. The participants who had experienced a stroke between 1999 and 2003 were excluded and were randomly selected from the NHIRD. The incidence of stroke (ICD-9-CM code 430-438 and patient survival after stroke were calculated for both groups using data from the NIHRD between 2004 and 2010. A Cox proportional-hazards model was used to compare the seven-year stroke-free survival rate and all-cause mortality rate across the two cohorts after adjusting for confounding risk factors. RESULTS: A total of 472 (2.81% patients with bipolar disorder and 1,443 (2.14% controls had strokes over seven years. Patients with bipolar disorder were 1.24 times more likely to have a stroke (95% CI = 1.12-1.38; p<0.0001 after adjusting for demographic characteristics and comorbid medical conditions. In addition, 513 (26.8% patients who had a stroke died during the follow-up period. The all-cause mortality hazard ratio for patients with bipolar disorder was 1.28 (95% CI = 1.06-1.55; p = 0.012 after adjusting for patient, physician and hospital variables. CONCLUSIONS: The likelihood of developing a stroke was greater among patients with bipolar disorder than controls, and the all-cause mortality rate was higher among patients with bipolar disorder than controls during a seven-year follow-up period.

  20. Solid cancer incidence among Chinese medical diagnostic x-ray workers, 1950-1995: Estimation of radiation-related risks.

    Science.gov (United States)

    Sun, Zhijuan; Inskip, Peter D; Wang, Jixian; Kwon, Deukwoo; Zhao, Yongcheng; Zhang, Liangan; Wang, Qin; Fan, Saijun

    2016-06-15

    The objective of this study was to estimate solid cancer risk attributable to long-term, fractionated occupational exposure to low doses of ionizing radiation. Based on cancer incidence for the period 1950-1995 in a cohort of 27,011 Chinese medical diagnostic X-ray workers and a comparison cohort of 25,782 Chinese physicians who did not use X-ray equipment in their work, we used Poisson regression to fit excess relative risk (ERR) and excess absolute risk (EAR) dose-response models for incidence of all solid cancers combined. Radiation dose reconstruction was based on a previously published method that relied on simulating measurements for multiple X-ray machines, workplaces and working conditions, information about protective measures, including use of lead aprons, and work histories. The resulting model was used to estimate calendar year-specific badge dose calibrated as personal dose equivalent (Sv). To obtain calendar year-specific colon doses (Gy), we applied a standard organ conversion factor. A total of 1,643 cases of solid cancer were identified in 1.45 million person-years of follow-up. In both ERR and EAR models, a statistically significant radiation dose-response relationship was observed for solid cancers as a group. Averaged over both sexes, and using colon dose as the dose metric, the estimated ERR/Gy was 0.87 (95% CI: 0.48, 1.45), and the EAR was 22 per 10(4)PY-Gy (95% CI: 14, 32) at age 50. We obtained estimates of the ERR and EAR of solid cancers per unit dose that are compatible with those derived from other populations chronically exposed to low dose-rate occupational or environmental radiation.

  1. Mapping and converting essential Federal Geographic Data Committee (FGDC) metadata into MARC21 and Dublin Core: towards an alternative to the FGDC Clearinghouse

    Science.gov (United States)

    Chandler, A.; Foley, D.; Hafez, A.M.

    2000-01-01

    The purpose of this article is to raise and address a number of issues related to the conversion of Federal Geographic Data Committee metadata into MARC21 and Dublin Core. We present an analysis of 466 FGDC metadata records housed in the National Biological Information Infrastructure (NBII) node of the FGDC Clearinghouse, with special emphasis on the length of fields and the total length of records in this set. One of our contributions is a 34 element crosswalk, a proposal that takes into consideration the constraints of the MARC21 standard as implemented in OCLC's World Cat and the realities of user behavior.

  2. Geographic incidence of human West Nile virus in northern Virginia, USA, in relation to incidence in birds and variations in urban environment.

    Science.gov (United States)

    Liu, Hua; Weng, Qihao; Gaines, David

    2011-09-15

    Previous studies have analyzed the number and location of bird infections with human incidence of West Nile virus (WNV) as well as the effects of environmental and socioeconomic factors on WNV propagation. However, such associations require more quantitative analyses. This study is intended to quantitatively analyze the relationship in eight counties/independent cities in the northern Virginia, based on an integrated analysis of spatially explicit information on precipitation, land cover, infrastructure, and demographic data using Geographical Information Systems, remote sensing, and statistics. Results show that bird infections in years 2002-2003 were closely associated with low to medium level of impervious surface with certain percentage of canopy and precipitation. Environmental and socioeconomic factors such as percentages of impervious surface, canopy, senior population (65 and older), old houses, bird risk areas, and low-income population were important indicators of human WNV risk in 2002. Limited impervious surface with some canopy provides suitable habitats for WNV transmission, where bird-feeding mosquitoes can forage for blood meals from nesting/roosting birds. Certain socioeconomic conditions such as old houses were linked with human infections by providing favorable environmental conditions, i.e., mature trees with abundant canopy and settled storm sewer systems. It should be noted that the current results may be biased toward urban environments, where dead birds were more likely found, and because the sampling efforts for the bird mortality were rather based on local residents' reports than a designed random sampling method. This geospatial study contributes toward better targeting of WNV prevention within the study area. It also provides an example of how geospatial methods and variables may be used in understanding the ecology of human WNV risk for other areas. PMID:21802710

  3. The incidence of water-related diseases in the Brak area, Libya from 1977 to 1979, before and after the installation of water treatment plants.

    Science.gov (United States)

    Ghannoum, M A; Moore, K E; Al-Dulaimi, M; Nasr, M

    1981-09-01

    The incidence of nine water-related diseases in the Brak oases of the Sahara desert, before and after the installation of water treatment plants, are reported. Immediately following installation of the plants there was a drop in the incidence of most of the water related diseases. There then followed a gradual deterioration in the treatment plants and within a year the incidence of four of the diseases was again rising. Furthermore neither malaria or giardiases showed any drop in incidence over the study period. Bacillary dysentary, infectious hepatitis and bilharzia did however drop significantly over the three years. A correlation between bacillary dysentary and the mean noon-time temperature for two of the three years was noted.

  4. Health-Related Quality of Life in Children with Celiac Disease: A Study Based on the Critical Incident Technique

    Directory of Open Access Journals (Sweden)

    Carlo Catassi

    2013-11-01

    Full Text Available Celiac Disease (CD is a chronic autoimmune disease triggered by dietary gluten. Gluten avoidance, which is the only available treatment for CD, could impact on quality of life of children with CD. We present the results of a qualitative study on the emotional impact of gluten free diet (GFD on the everyday life of children affected with CD. We investigated 76 celiac patients aged 2–18 years (average age: 9.5 years. By using the Critical Incident Technique (CIT, we defined emotions related to difficulties and awkward situations experienced by the patients. Written answers to open-ended questions from either children (older than 8 years and parents (children younger than 8 years were analyzed qualitatively. We found 80 dilemmas experienced in three different arenas (food situations at school, meals at home, meals outside and characterized lived experiences of children with CD in everyday life (specific emotions, difficulties in relationships and in management of daily life. Children with CD experience strong emotions related to the GFD, permeating several aspects of everyday life. These dilemmas may be missed by a conventional, questionnaire-based approach to the psycho-social consequences of CD treatment.

  5. MO-G-BRE-06: Metrics of Success: Measuring Participation and Attitudes Related to Near-Miss Incident Learning Systems

    International Nuclear Information System (INIS)

    Purpose: Interest in incident learning systems (ILS) for improving safety and quality in radiation oncology is growing, as evidenced by the upcoming release of the national ILS. However, an institution implementing such a system would benefit from quantitative metrics to evaluate performance and impact. We developed metrics to measure volume of reporting, severity of reported incidents, and changes in staff attitudes over time from implementation of our institutional ILS. Methods: We analyzed 2023 incidents from our departmental ILS from 2/2012–2/2014. Incidents were prospectively assigned a near-miss severity index (NMSI) at multidisciplinary review to evaluate the potential for error ranging from 0 to 4 (no harm to critical). Total incidents reported, unique users reporting, and average NMSI were evaluated over time. Additionally, departmental safety attitudes were assessed through a 26 point survey adapted from the AHRQ Hospital Survey on Patient Safety Culture before, 12 months, and 24 months after implementation of the incident learning system. Results: Participation in the ILS increased as demonstrated by total reports (approximately 2.12 additional reports/month) and unique users reporting (0.51 additional users reporting/month). Also, the average NMSI of reports trended lower over time, significantly decreasing after 12 months of reporting (p<0.001) but with no significant change at months 18 or 24. In survey data significant improvements were noted in many dimensions, including perceived barriers to reporting incidents such as concern of embarrassment (37% to 18%; p=0.02) as well as knowledge of what incidents to report, how to report them, and confidence that these reports were used to improve safety processes. Conclusion: Over a two-year period, our departmental ILS was used more frequently, incidents became less severe, and staff confidence in the system improved. The metrics used here may be useful for other institutions seeking to create or evaluate

  6. MO-G-BRE-06: Metrics of Success: Measuring Participation and Attitudes Related to Near-Miss Incident Learning Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nyflot, MJ; Kusano, AS; Zeng, J; Carlson, JC; Novak, A; Sponseller, P; Jordan, L; Kane, G; Ford, EC [University of Washington, Seattle, WA (United States)

    2014-06-15

    Purpose: Interest in incident learning systems (ILS) for improving safety and quality in radiation oncology is growing, as evidenced by the upcoming release of the national ILS. However, an institution implementing such a system would benefit from quantitative metrics to evaluate performance and impact. We developed metrics to measure volume of reporting, severity of reported incidents, and changes in staff attitudes over time from implementation of our institutional ILS. Methods: We analyzed 2023 incidents from our departmental ILS from 2/2012–2/2014. Incidents were prospectively assigned a near-miss severity index (NMSI) at multidisciplinary review to evaluate the potential for error ranging from 0 to 4 (no harm to critical). Total incidents reported, unique users reporting, and average NMSI were evaluated over time. Additionally, departmental safety attitudes were assessed through a 26 point survey adapted from the AHRQ Hospital Survey on Patient Safety Culture before, 12 months, and 24 months after implementation of the incident learning system. Results: Participation in the ILS increased as demonstrated by total reports (approximately 2.12 additional reports/month) and unique users reporting (0.51 additional users reporting/month). Also, the average NMSI of reports trended lower over time, significantly decreasing after 12 months of reporting (p<0.001) but with no significant change at months 18 or 24. In survey data significant improvements were noted in many dimensions, including perceived barriers to reporting incidents such as concern of embarrassment (37% to 18%; p=0.02) as well as knowledge of what incidents to report, how to report them, and confidence that these reports were used to improve safety processes. Conclusion: Over a two-year period, our departmental ILS was used more frequently, incidents became less severe, and staff confidence in the system improved. The metrics used here may be useful for other institutions seeking to create or evaluate

  7. Alignment of single-case design (SCD) research with individuals who are deaf or hard of hearing with the what Works Clearinghouse standards for SCD research.

    Science.gov (United States)

    Wendel, Erica; Cawthon, Stephanie W; Ge, Jin Jin; Beretvas, S Natasha

    2015-04-01

    The authors assessed the quality of single-case design (SCD) studies that assess the impact of interventions on outcomes for individuals who are deaf or hard-of-hearing (DHH). More specifically, the What Works Clearinghouse (WWC) standards for SCD research were used to assess design quality and the strength of evidence of peer-reviewed studies available in the peer-reviewed, published literature. The analysis yielded four studies that met the WWC standards for design quality, of which two demonstrated moderate to strong evidence for efficacy of the studied intervention. Results of this review are discussed in light of the benefits and the challenges to applying the WWC design standards to research with DHH individuals and other diverse, low-incidence populations.

  8. Anti-tuberculosis drugs related hepatotoxicity; incidence, risk factors, pattern of changes in liver enzymes and outcome

    Directory of Open Access Journals (Sweden)

    H Khalili

    2009-10-01

    Full Text Available "nBackground and the purpose of the study: Tuberculosis is a curable disease if diagnosed and treated properly with anti-tuberculosis drugs. These drugs can cause severe adverse reactions including hepatotoxicity.The goal of this study was to evaluate the rate and the time of incidence, pattern of alterations in liver enzyme, risk factors and outcome of anti-tuberculosis drugs induced hepatotoxicity in Iranian Tuberculosis patients. "nMethod: In a prospective cohort study, 102 patients (68 male, 34 female, mean age 43.21±18 years with tuberculosis diagnosis were followed during anti-tuberculosis drug treatment course. Drug related hepatotoxicity was defined as increase in serum alanine aminotransfrase or aspartate aminotransfrase greater than three or five times of the upper limit of normal, with or without symptoms of hepatitis, respectively. "nResults: anti-tuberculosis induced hepatotoxicity was detected in 32 (31.37% of the patients. Human immunodeficiency virus and hepatitis C virus infections, concomitant use of hepatotoxic drugs, and abnormal baseline serum alanine aminotransfrase and aspartate aminotransfrase level were risk factors for anti-tuberculosis drugs induced hepatotoxicity. "nConclusion: Anti-tuberculosis drugs induced hepatotoxicity is a major problem in Iranian tuberculosis patients and cause treatment interruption in 31.37% of patients.

  9. Incidence of Incomplete Excision in Surgically Treated Cutaneous Squamous Cell Carcinoma and Identification of the Related Risk Factors

    Directory of Open Access Journals (Sweden)

    Sara Sabouri Rad

    2011-12-01

    Full Text Available Squamous cell carcinoma (SCC is the second most common type of skin cancer with potential risks for metastasis and recurrence if left untreated or incompletely excised. This case series study was designed to determine the frequency of incompletely excised SCCs and the related risk factors. A total of 273 SCCs (253 patients excised in Razi dermatology hospital of Tehran from 2006-2008, were evaluated and were analyzed by Chi-square or t-test. The incidence of incomplete excision was 17.58 % and deep margin involvement was observed in 73% of lesions. Risk factors associated with incomplete excision of SCCs were being female, location of the tumors (in particular the lesions on lateral canthus, upper lip, foot, forehead, cheek, neck, nose and ear, large lesions and grafting method of repair. There was no statistically significant difference for the age, degree of histological differentiation, childhood history of radiotherapy for tinea capitis and the type of anesthesia. More care should be taken for high risk SCCs as complete excision avoids potential risk of recurrence and metastasis.

  10. Lindamood Phoneme Sequencing[R] (LiPS[R]). What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2010

    2010-01-01

    The "Lindamood Phoneme Sequencing"[R] ("LiPS"[R]) program (formerly called the "Auditory Discrimination in Depth"[R] ["ADD"] program) is designed to teach students the skills they need to decode words and to identify individual sounds and blends in words. Thirty-one studies reviewed by the What Works Clearinghouse (WWC) investigated the effects of…

  11. Oregon Intellectual Freedom Clearinghouse. Fourteenth Annual Report, July 1, 2000-June 30, 2001.

    Science.gov (United States)

    Oregon State Library, Salem.

    The goal of the Oregon Intellectual Freedom Clearinghouse is to uphold the principles of the Library Bill of Rights in all types of libraries by improving communication between librarians, board members, professional associations, and other concerned groups in Oregon about challenges to intellectual freedom, and by increasing awareness as to how…

  12. Oregon Intellectual Freedom Clearinghouse. Thirteenth Annual Report, July 1, 1999-June 30, 2000.

    Science.gov (United States)

    Oregon State Library, Salem.

    The goal of the Oregon Intellectual Freedom Clearinghouse is to uphold the principles of the Library Bill of Rights in all types of libraries by improving communication between librarians, board members, professional associations, and other concerned groups in Oregon about challenges to intellectual freedom, and by increasing awareness as to how…

  13. News from International Clearinghouse on Children and Violence on the Screen (ICCVOS), 2001.

    Science.gov (United States)

    von Feilitzen, Cecilia, Ed.

    2001-01-01

    This document represents the only issue of UNESCO International Clearinghouse on Children and Violence on the Screen's newsletter published in 2001. The report describes research findings concerning children and media violence, children's media use, and activities aimed at limiting gratuitous media violence. One article summarizes three workshops…

  14. News from the International Clearinghouse on Children and Violence on the Screen (ICCVOS), 2000.

    Science.gov (United States)

    von Feilitzen, Cecilia, Ed.

    2000-01-01

    This document is comprised of the year 2000 reports from the UNESCO International Clearinghouse on Children and Violence on the Screen. The two issues describe research findings concerning children and media violence, children's media use, and activities aimed at limiting gratuitous media violence. The first issue includes articles addressing…

  15. News from International Clearinghouse on Children and Violence on the Screen (ICCVOS), 2002.

    Science.gov (United States)

    von Feilitzen, Cecilia, Ed.

    2002-01-01

    This document is comprised of the two issues of the UNESCO International Clearinghouse on Children and Violence on the Screen's newsletter published in 2002, describing research findings concerning children and media violence, children's media use, and activities aimed at limiting gratuitous media violence. The first is a double issue that begins…

  16. 75 FR 34441 - Office of Safe and Drug-Free Schools; Overview Information; Educational Facilities Clearinghouse...

    Science.gov (United States)

    2010-06-17

    ..., operation, and maintenance of public nursery and pre-kindergarten, kindergarten-through-grade-12, and higher... priority to provide a Clearinghouse for public nursery, pre-kindergarten, and kindergarten- through-grade... maintenance of safe, healthy, high-performance public facilities for nursery and pre-...

  17. National Clearinghouse for Drug Abuse Information Report Series, Series 15, No. 1.

    Science.gov (United States)

    National Inst. on Drug Abuse (DHEW/PHS), Rockville, MD. National Clearinghouse for Drug Abuse Information.

    Concerned with clarifying some of the more complex issues in drug abuse, the National Clearinghouse for Drug Abuse Information has prepared this special report on mescaline. Background information is provided through a summary of its history, legal status, and the opinions of authorities in the field. Significant research on the subject is…

  18. University posts beta version of Smart Grid Information Clearinghouse Web portal to invite comments, suggestions on usability

    OpenAIRE

    Micale, Barbara L.

    2010-01-01

    Virginia Tech announced today that it has posted a beta version of the Smart Grid Information Clearinghouse (SGIC) Web portal to invite comments and suggestions on usability from both consumers and the smart grid community.

  19. Intakes of several nutrients are associated with incidence of arsenic-related keratotic skin lesions in Bangladesh.

    Science.gov (United States)

    Melkonian, Stephanie; Argos, Maria; Chen, Yu; Parvez, Faruque; Pierce, Brandon; Ahmed, Alauddin; Islam, Tariqul; Ahsan, Habibul

    2012-12-01

    Risk of skin lesions due to chronic arsenic exposure can be further affected by nutrient intake. We prospectively evaluated the association of nutrient intake and gender with incident skin lesions using data from the Health Effects of Arsenic Longitudinal Study (HEALS) in Araihazar, Bangladesh. Discrete time hazard models were used to estimate these effects in stratified analyses based on skin lesion severity. Overall, we observed significant associations between low intakes of various nutrients (retinol, calcium, fiber, folate, iron, riboflavin, thiamin, and vitamins A, C, and E) and skin lesion incidence, particularly for keratotic skin lesions. Associations for vitamins C and E showed significant linear trends. Gender-specific analyses revealed an inverse association between the lowest quartile of nutrient intake and keratotic skin lesion incidence for retinol equivalents, calcium, folate, iron, and fiber among women. Interactions by gender were observed for retinol equivalents (P-interaction = 0.03), calcium (P-interaction = 0.04), vitamin A (P-interaction = 0.03), and riboflavin (P-interaction = 0.04) with the incidence of keratotic skin lesions. Understanding differential susceptibility to skin lesion incidence based on nutrient intake will help researchers develop targeted interventions to prevent health consequences of arsenic poisoning in Bangladesh and beyond.

  20. Making sense of diversity in the workplace: organizational justice and language abstraction in employees' accounts of diversity-related incidents.

    Science.gov (United States)

    Roberson, Quinetta M; Stevens, Cynthia Kay

    2006-03-01

    To discern patterns of employee sense-making about workplace diversity, the authors analyzed 751 natural language accounts of diversity incidents from 712 workers in one department of a large organization. Six generic incident types emerged: discrimination, representation, treatment by management, work relationships, respect between groups, and diversity climates. Consistent with hypotheses, incidents that respondents viewed as negative, accounts from women, and those involving members of respondents' in-groups were more likely to cite justice issues. Partially consistent with research on the linguistic intergroup bias, both negative and positive accounts involving out-group members and accounts from men were more likely to be expressed using abstract verb forms. The authors discuss future opportunities to integrate research on diversity, justice, and the linguistic category model. PMID:16551190

  1. Making sense of diversity in the workplace: organizational justice and language abstraction in employees' accounts of diversity-related incidents.

    Science.gov (United States)

    Roberson, Quinetta M; Stevens, Cynthia Kay

    2006-03-01

    To discern patterns of employee sense-making about workplace diversity, the authors analyzed 751 natural language accounts of diversity incidents from 712 workers in one department of a large organization. Six generic incident types emerged: discrimination, representation, treatment by management, work relationships, respect between groups, and diversity climates. Consistent with hypotheses, incidents that respondents viewed as negative, accounts from women, and those involving members of respondents' in-groups were more likely to cite justice issues. Partially consistent with research on the linguistic intergroup bias, both negative and positive accounts involving out-group members and accounts from men were more likely to be expressed using abstract verb forms. The authors discuss future opportunities to integrate research on diversity, justice, and the linguistic category model.

  2. Myocardial infarction 1979-1988 in Denmark: secular trends in age-related incidence, in-hospital mortality and complications

    DEFF Research Database (Denmark)

    Hildebrandt, P; Jensen, G; Køber, L;

    1994-01-01

    All admissions to a coronary care unit (CCU) in Copenhagen County were prospectively registered over a 10-year period, from 1979 to 1988, i.e. after the introduction of CCUs but before the era of intervention with thrombolytic or prophylactic medical treatment. The catchment area remained nearly ...... the incidence of ventricular fibrillation, heart failure and pulmonary oedema was unchanged....

  3. Incidence and etiology of sports-related sudden cardiac death in Denmark--implications for preparticipation screening

    DEFF Research Database (Denmark)

    Holst, Anders Gaarsdal; Winkel, Bo Gregers; Theilade, Juliane;

    2010-01-01

    to 5 per year) cases of SrSCD were found, 8 of which had antecedent symptoms. The incidence rate was 1.21 (95% confidence interval [CI]: 0.68 to 2.00) per 100,000 athlete person-years. The most common autopsy findings were arrhythmogenic right ventricular cardiomyopathy (n = 4), sudden unexplained...... death (n = 4), and coronary artery disease (n = 2). The incidence of SCD in the general population age 12 to 35 was 3.76 (95% CI: 3.42 to 4.14) per 100,000 person-years. CONCLUSION: In Denmark, SrSCD is a rare occurrence and the incidence rate is lower than that of SCD in the general population......) and to compare this to the incidence of sudden cardiac death (SCD) in the background population. METHODS: All 5,662 death certificates for decedents in the period 2000 to 2006 in the age group 12 to 35 years in Denmark were read independently by 2 physicians to identify cases of SCD. Information from autopsy...

  4. The incidence of SCN1A-related Dravet syndrome in Denmark is 1:22,000

    DEFF Research Database (Denmark)

    Bayat, Allan; Hjalgrim, Helle; Møller, Rikke S.

    2015-01-01

    Dravet syndrome is a severe infantile-onset epileptic encephalopathy associated with mutations in the sodium channel alpha-1 subunit gene SCN1A. We aimed to describe the incidence of Dravet syndrome in the Danish population. Based on a 6-year birth cohort from 2004 to 2009, we propose an incidenc...

  5. Cancer incidence in children and young adults did not increase relative to parental exposure to atomic bombs.

    Science.gov (United States)

    Izumi, S; Koyama, K; Soda, M; Suyama, A

    2003-11-01

    We have examined whether parental exposure to atomic bomb radiation has led to increased cancer risks among the offspring. We studied 40,487 subjects born from May 1946 through December 1984 who were cancer-free in January 1958. One or both parents were in Hiroshima or Nagasaki at the time of the bombing and for childbirth. Using population-based tumor registry data we analyzed cancer incidence data from 1958 to 1997 by Cox regression models, and we examined the effects of both paternal and maternal irradiation with adjustment for city, sex, birth year, and migration. During follow-up, 575 solid tumor cases and 68 hematopoietic tumor cases were diagnosed. Median age at diagnosis was 39.7 years. Median doses were 143 millisierverts for 15,992 exposed (5+ millisierverts or unknown dose) fathers and 133 millisierverts for 10,066 exposed mothers. Cancer incidence was no higher for subjects with exposed parents than for the reference subjects (0-4 millisierverts), nor did the incidence rates increase with increasing dose. For 3568 subjects with two exposed parents, the adjusted risk ratio for all cancer was 0.97 (95% confidence interval 0.70-1.36). Because of the small number of cases, however, we cannot exclude an increase in cancer incidence at this time. PMID:14583774

  6. Vehicular Traffic–Related Polycyclic Aromatic Hydrocarbon Exposure and Breast Cancer Incidence: The Long Island Breast Cancer Study Project (LIBCSP)

    OpenAIRE

    Mordukhovich, Irina; Beyea, Jan; Herring, Amy H.; Hatch, Maureen; Stellman, Steven D.; Teitelbaum, Susan L.; Richardson, David B; Millikan, Robert C.; Engel, Lawrence S; Shantakumar, Sumitra; Steck, Susan E.; Neugut, Alfred I; Rossner, Pavel; Santella, Regina M.; Gammon, Marilie D.

    2015-01-01

    Background Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental pollutants, known human lung carcinogens, and potent mammary carcinogens in laboratory animals. However, the association between PAHs and breast cancer in women is unclear. Vehicular traffic is a major ambient source of PAH exposure. Objectives Our study aim was to evaluate the association between residential exposure to vehicular traffic and breast cancer incidence. Methods Residential histories of 1,508 particip...

  7. The Prevalence of Helicobacter pylori Virulence Factors in Bhutan, Vietnam, and Myanmar Is Related to Gastric Cancer Incidence

    Directory of Open Access Journals (Sweden)

    Tran Thi Huyen Trang

    2015-01-01

    Full Text Available Gastric cancer is a significant health problem in Asia. Although the prevalence of Helicobacter pylori infection is similar in Bhutan, Vietnam, and Myanmar, the incidence of gastric cancer is highest in Bhutan, followed by Vietnam and Myanmar. We hypothesized that H. pylori virulence factors contribute to the differences. The status of cagA, vacA, jhp0562, and β-(1,3galT(jhp0563 was examined in 371 H. pylori-infected patients from Bhutan, Vietnam, and Myanmar. Each virulence factor could not explain the difference of the incidence of gastric cancer. However, the prevalence of quadruple-positive for cagA, vacA s1, vacA m1, and jhp0562-positive/β-(1,3galT-negative was significantly higher in Bhutan than in Vietnam and Myanmar and correlated with gastric cancer incidence. Moreover, gastritis-staging scores measured by histology of gastric mucosa were significantly higher in quadruple-positive strains. We suggest that the cagA, vacA s1, vacA m1, and jhp0562-positive/β-(1,3galT-negative genotype may play a role in the development of gastric cancer.

  8. Relation between grazing incident X-ray diffraction and surface defects in silicon doped GaAs

    International Nuclear Information System (INIS)

    Grazing incident X-ray diffraction is used to study oval defects on the surface of silicon doped GaAs layers grown by means of molecular beam epitaxy. The amplitude of the (1 1 3) peak from the diffraction data is associated with the defect density obtained from scanning electron microscopy images. These images reveal two different kinds of defects for all samples. It was proven that variations in the silicon effusion cell temperature affect the defect density. By increasing the cell temperature the defect density increases.

  9. Vitamin C, Vitamin E and Beta-Carotene in Relation to Common Cold Incidence in Male Smokers

    OpenAIRE

    HemilÀ Harri; Kaprio Jaakko; Albanes Demetrius; Heinonen Olli P; Virtamo Jarmo

    2010-01-01

    We evaluated the role of dietary vitamin C, vitamin E, and beta-carotene, as well as long-term vitamin E and beta-carotene supplementation, on the incidence of common cold episodes. A cohort of 21,796 male smokers was drawn from the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study, which examined the effects of 50 mg per day vitamin E and 20 mg per day beta-carotene on lung cancer. Diet and background characteristics were recorded at the study entry, and subjects were queried three time...

  10. Incidence of leukemia among atomic bomb survivors in relation to neutron and gamma dose, Hiroshima and Nagasaki, 1950-71

    International Nuclear Information System (INIS)

    The incidence of leukemia during 1950-71 in the fixed mortality sample of atomic bomb survivors in Hiroshima and Nagasaki has been analyzed as a function of individual gamma and neutron kerma and marrow dose. Two dose response models were tested for each of acute leukemia, chronic granulocytic leukemia, and all types of leukemia, respectively. Each model postulates that leukemia incidence depends upon the sum of the separate risks imposed by the gamma ray and neutron doses; in Model I both are assumed to be directly proportional to the respective doses, while Model II assumes that while the risk from neutrons is directly proportional to the dose, the risk from gamma rays is proportional to dose-squared. Weighted regression analyses were performed for each model. When the two models were fitted to the data for all types of leukemia, the estimated regression coefficients corresponding to the neutron and gamma ray doses both differed significantly from zero, for each model. However, when analysis was restricted to acute leukemia, both the neutron and gamma ray coefficients were significant only for Model II, and with respect to chronic granulocytic leukemia, only the coefficient of the neutron dose was significant, using either Model I or Model II. It appeared that the responses of the two leukemia types differed by type of radiation. If the chronic granulocytic and acute leukemias are considered together, the Model II appears to fit the data slightly better than Model I, but neither models is rejected by the data. (author)

  11. Organizing and Making Sense of the Literature: Arthur M. Cohen as Director of the ERIC Clearinghouse for Community Colleges, 1966-2003

    Science.gov (United States)

    Palmer, James C.

    2007-01-01

    A major part of Arthur M. Cohen's scholarly legacy is the archive of documents and journal articles catalogued by the ERIC Clearinghouse for Community Colleges, which he led throughout its entire 37-year history (1966-2003). As Clearinghouse director, Cohen oversaw its document acquisition and cataloguing operations, as well as its extensive…

  12. Patient- and therapy-related factors associated with the incidence of xerostomia in nasopharyngeal carcinoma patients receiving parotid-sparing helical tomotherapy

    OpenAIRE

    Tsair-Fwu Lee; Ming-Hsiang Liou; Hui-Min Ting; Liyun Chang; Hsiao-Yi Lee; Stephen Wan Leung; Chih-Jen Huang; Pei-Ju Chao

    2015-01-01

    We investigated the incidence of moderate to severe patient-reported xerostomia among nasopharyngeal carcinoma (NPC) patients treated with helical tomotherapy (HT) and identified patient- and therapy-related factors associated with acute and chronic xerostomia toxicity. The least absolute shrinkage and selection operator (LASSO) normal tissue complication probability (NTCP) models were developed using quality-of-life questionnaire datasets from 67 patients with NPC. For acute toxicity, the do...

  13. Active and passive smoking in relation to lung cancer incidence in the Women's Health Initiative Observational Study prospective cohort†

    Science.gov (United States)

    Wang, A.; Kubo, J.; Luo, J.; Desai, M.; Hedlin, H.; Henderson, M.; Chlebowski, R.; Tindle, H.; Chen, C.; Gomez, S.; Manson, J. E.; Schwartz, A. G.; Wactawski-Wende, J.; Cote, M.; Patel, M. I.; Stefanick, M. L.; Wakelee, H. A.

    2015-01-01

    Background Lung cancer is the leading cause of worldwide cancer deaths. While smoking is its leading risk factor, few prospective cohort studies have reported on the association of lung cancer with both active and passive smoking. This study aimed to determine the relationship between lung cancer incidence with both active and passive smoking (childhood, adult at home, and at work). Patients and methods The Women's Health Initiative Observational Study (WHI-OS) was a prospective cohort study conducted at 40 US centers that enrolled postmenopausal women from 1993 to 1999. Among 93 676 multiethnic participants aged 50–79, 76 304 women with complete smoking and covariate data comprised the analytic cohort. Lung cancer incidence was calculated by Cox proportional hazards models, stratified by smoking status. Results Over 10.5 mean follow-up years, 901 lung cancer cases were identified. Compared with never smokers (NS), lung cancer incidence was much higher in current [hazard ratio (HR) 13.44, 95% confidence interval (CI) 10.80–16.75] and former smokers (FS; HR 4.20, 95% CI 3.48–5.08) in a dose-dependent manner. Current and FS had significantly increased risk for all lung cancer subtypes, particularly small-cell and squamous cell carcinoma. Among NS, any passive smoking exposure did not significantly increase lung cancer risk (HR 0.88, 95% CI 0.52–1.49). However, risk tended to be increased in NS with adult home passive smoking exposure ≥30 years, compared with NS with no adult home exposure (HR 1.61, 95% CI 1.00–2.58). Conclusions In this prospective cohort of postmenopausal women, active smoking significantly increased risk of all lung cancer subtypes; current smokers had significantly increased risk compared with FS. Among NS, prolonged passive adult home exposure tended to increase lung cancer risk. These data support continued need for smoking prevention and cessation interventions, passive smoking research, and further study of lung cancer risk factors

  14. Incident Report - Legacy

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Incident Report is a mandatory post trip legal document observers fill out to report any enforcement related situations they have encountered on an observed...

  15. Clinical management of the induction of labor in intrauterine fetal death: evaluation of incidence of cesarean section and related conditions

    Directory of Open Access Journals (Sweden)

    Maria Isabel do Nascimento

    2014-03-01

    Full Text Available OBJECTIVE: To assess the incidence and conditions associated with cesarean section in a cohort of pregnant women with intrauterine fetal death (IUFD, and clinical management to anticipate the childbirth. METHODS: It was a retrospective cohort study with 163 mothers with IUFD, at the second half of pregnancy, who were managed to anticipate childbirth using pharmacological preparations and/or a mechanical method (Foley catheter in a teaching hospital in Rio de Janeiro State, Brazil. Cox regression was used to evaluate the effect of the clinical methods on the kind of delivery. RESULTS: The Subgroups A (misoprostol or Oxytocin, B (misoprostol and Oxytocin, and C (Foley catheter alone or combined with misoprostol and/or Oxytocin were formed according to the applied methods. Nine out of 163 cases ended with cesarean section. The incidence of cesarean section was 3.5 per 1,000 people-hours, meaning that a pregnant woman with IUFD had a 15.6% risk of cesarean section during the first 48 hours of clinical management to anticipate childbirth. The conditions significantly associated with the mode of delivery were placental abruption (HR: 44.97, having two or more previous cesarean deliveries (HR: 10.03, and mechanical method with Foley catheter (HR: 5.01. CONCLUSION: Cesarean section was an essential conduct in this cohort and followed previous cesarean delivery and placental abruption. The effect of the mechanical method on the abdominal route suggests that the Foley catheter method was used in the most difficult cases and that the surgery was performed to ensure maternal health.

  16. lHCV-related burden of disease in Europe: a systematic assessment of incidence, prevalence, morbidity, and mortality

    Directory of Open Access Journals (Sweden)

    Siebert Uwe

    2009-01-01

    Full Text Available Abstract Background Hepatitis C virus (HCV is a leading cause of chronic liver disease, end-stage cirrhosis, and liver cancer, but little is known about the burden of disease caused by the virus. We summarised burden of disease data presently available for Europe, compared the data to current expert estimates, and identified areas in which better data are needed. Methods Literature and international health databases were systematically searched for HCV-specific burden of disease data, including incidence, prevalence, mortality, disability-adjusted life-years (DALYs, and liver transplantation. Data were collected for the WHO European region with emphasis on 22 countries. If HCV-specific data were unavailable, these were calculated via HCV-attributable fractions. Results HCV-specific burden of disease data for Europe are scarce. Incidence data provided by national surveillance are not fully comparable and need to be standardised. HCV prevalence data are often inconclusive. According to available data, an estimated 7.3–8.8 million people (1.1–1.3% are infected in our 22 focus countries. HCV-specific mortality, DALY, and transplantation data are unavailable. Estimations via HCV-attributable fractions indicate that HCV caused more than 86000 deaths and 1.2 million DALYs in the WHO European region in 2002. Most of the DALYs (95% were accumulated by patients in preventable disease stages. About one-quarter of the liver transplants performed in 25 European countries in 2004 were attributable to HCV. Conclusion Our results indicate that hepatitis C is a major health problem and highlight the importance of timely antiviral treatment. However, data on the burden of disease of hepatitis C in Europe are scarce, outdated or inconclusive, which indicates that hepatitis C is still a neglected disease in many countries. What is needed are public awareness, co-ordinated action plans, and better data. European physicians should be aware that many infections

  17. Detection of Breast Cancer with Mammography in the First Screening Round in Relation to Expected Incidence in Different Age Groups

    International Nuclear Information System (INIS)

    The ratio (R) of prevalence of screening-detected breast cancer in the first screening round (P) was compared with the expected incidence rate (I) for different age groups in several screening programs. Published data on the first screening round from three Swedish randomized trials and six counties with service screening were used. The women invited to take part in the screening were aged 40-74 years. Not only P and I but also R increased with increasing age. With the youngest age group as reference, the increase was statistically significant for both invasive cancer and invasive cancer and carcinoma in situ together. The studied ratio (R) can be thought of as a measure of efficiency in detecting breast cancer cases in mammography screening. The reasons for the increase are probably that the breast tissue of younger women is denser, which makes the cancer more difficult to detect by mammography, and that slow-growing cancers tend to appear more frequently in older women

  18. The Zelnorm epidemiologic study (ZEST: a cohort study evaluating incidence of abdominal and pelvic surgery related to tegaserod treatment

    Directory of Open Access Journals (Sweden)

    Seeger John D

    2012-11-01

    Full Text Available Abstract Background Pre-marketing clinical studies of tegaserod suggested an increased risk of abdominal surgery, particularly cholecystectomy. We sought to quantify the association between tegaserod use and the occurrence of abdominal or pelvic surgery, including cholecystectomy. Methods This cohort study was conducted within an insured population. Tegaserod initiators and similar persons who did not initiate tegaserod were followed for up to six months for the occurrence of abdominal or pelvic surgery. Surgical procedures were identified from health insurance claims validated by review of medical records. The incidence of confirmed outcomes was compared using both as-matched and as-treated analyses. Results Among 2,762 tegaserod initiators, there were 94 abdominal or pelvic surgeries (36 gallbladder: among 2,762 comparators there were 134 abdominal or pelvic surgeries (37 gallbladder (hazard ratio HR] = 0.70, 95% confidence interval [C.I.] = 0.54-0.91 overall, HR = 0.98, 95% C.I. = 0.62-1.55 for gallbladder. Current tegaserod exposure compared to nonexposure was associated with a rate ratio [RR] of 0.68 (95% C.I. = 0.48-0.95 overall, while the RR was 0.99 (95% C.I. = 0.56-1.77 for gallbladder surgery. Conclusions In this study, tegaserod use was not found to increase the risk of abdominal or pelvic surgery nor the specific subset of gallbladder surgery.

  19. Incidence of bone metastases and skeletal-related events in breast cancer patients: A population-based cohort study in Denmark

    Directory of Open Access Journals (Sweden)

    Fryzek Jon P

    2011-01-01

    Full Text Available Abstract Background Breast cancer (BrCa is the most commonly diagnosed cancer among women in the industrialized world. More than half of women presenting with metastatic BrCa develop bone metastases. Bone metastases increase the risk of skeletal-related events (SREs, defined as pathological fractures, spinal cord compression, bone pain requiring palliative radiotherapy, and orthopaedic surgery. Both bone metastases and SREs are associated with unfavorable prognosis and greatly affect quality of life. Few epidemiological data exist on SREs after primary diagnosis of BrCa and subsequent bone metastasis. We therefore estimated the incidence of bone metastases and SREs in newly-diagnosed BrCa patients in Denmark from 1999 through 2007. Methods We estimated the overall and annual incidence of bone metastases and SREs in newly-diagnosed breast cancer patients in Denmark from January 1, 1999 to December 31, 2007 using the Danish National Patient Registry (DNPR, which covers all Danish hospitals. We estimated the cumulative incidence of bone metastases and SREs and associated 95% confidence intervals (CI using the Kaplan-Meier method. Results Of the 35,912 BrCa patients, 178 (0.5% presented with bone metastases at the time of primary breast cancer diagnosis, and of these, 77 (43.2% developed an SRE during follow up. A total of 1,272 of 35,690 (3.6% BrCa patients without bone metastases at diagnosis developed bone metastases during a median follow-up time of 3.4 years. Among these patients, 590 (46.4% subsequently developed an SRE during a median follow-up time of 0.7 years. Incidence rates of bone metastases were highest the first year after the primary BrCa diagnosis, particularly among patients with advanced BrCa at diagnosis. Similarly, incidence rates of a first SRE was highest the first year after first diagnosis of a bone metastasis. Conclusions The high incidence of SREs following the first year after first diagnosis of a bone metastasis

  20. Incidence of Raynaud's phenomenon in relation to hand-arm vibration exposure among male workers at an engineering plant a cohort study

    Directory of Open Access Journals (Sweden)

    Lundström Ronnie

    2008-06-01

    Full Text Available Abstract Background The objective of this study was to assess the incidence of Raynaud's phenomenon in relation to hand-arm vibration exposure in a cohort consisting of male office and manual workers. Methods The baseline population consisted of 94 office and 147 manual workers at an engineering plant. Raynaud's phenomenon (RP was assessed at baseline and at follow up (at 5, 10 and 15 years. A retrospective and a prospective cohort analysis of data were done. Hand-arm vibration exposure dose was defined as the product of exposure duration and the weighted hand-arm vibration exposure value according to ISO 5349-1. Results The retrospective/prospective incidence of Raynaud's phenomenon was 16/14 per 1000 exposure years among exposed and 2.4/5.0 per 1000 years among the not exposed. The retrospective dose response curve based on 4 dose classes showed that class 2, 3 and 4 had similar response and showed higher incidence than the not-exposed. The dose with RP response to hand-arm vibration corresponded to a 10 year A(8 value between 0.4–1.0 m/s2. Conclusion The results indicate that the EU directive on an action value for hand-arm vibration of 2.5 m/s2 is not too low. Rather, it suggests that employers should take on actions even at exposure values of 1 m/s2A(8.

  1. Geoenvironmental factors related to high incidence of human urinary calculi (kidney stones) in Central Highlands of Sri Lanka.

    Science.gov (United States)

    Abeywickarama, Buddhika; Ralapanawa, Udaya; Chandrajith, Rohana

    2016-10-01

    An area with extremely high incidence of urinary calculi was investigated in the view of identifying the relationship between the disease prevalence and the drinking water geochemistry. The prevalence of the kidney stone disease in the selected Padiyapelella-Hanguranketa area in Central Highlands of Sri Lanka is significantly higher compared with neighboring regions. Drinking water samples were collected from water sources that used by clinically identified kidney stone patients and healthy people. A total of 83 samples were collected and analyzed for major anions and cations. The anions in the area varied in the order HCO3 (-) > Cl(-) > SO4 (2-) > NO3 (-) and cations varied in the order Ca(2+) > Mg(2+) > Na(+) > K(+) > Fe(2+). The dissolved silica that occurs as silicic acid (H4SiO4) in natural waters varied from 8.8 to 84 mg/L in prevalence samples, while it was between 9.7 and 65 mg/L for samples from non-prevalence locations. Hydrogeochemical data obtained from the two groups were compared using the Wilcoxon rank-sum test. It showed that pH, total hardness, Na(+), Ca(2+) and Fe(2+) had significant difference (p plots, Gibbs' plot and factor analysis indicated that the chemical composition of water sources in this area is strongly influenced by rock-water interactions, particularly the weathering of carbonate and silicate minerals. This study reveals a kind of association between stone formation and drinking water geochemistry as evident by the high hardness/calcium contents in spring water used by patients. PMID:26620679

  2. Neighbourhood socioeconomic inequalities in incidence of acute myocardial infarction: a cohort study quantifying age- and gender-specific differences in relative and absolute terms

    Directory of Open Access Journals (Sweden)

    Koopman Carla

    2012-08-01

    Full Text Available Abstract Background Socioeconomic status has a profound effect on the risk of having a first acute myocardial infarction (AMI. Information on socioeconomic inequalities in AMI incidence across age- gender-groups is lacking. Our objective was to examine socioeconomic inequalities in the incidence of AMI considering both relative and absolute measures of risk differences, with a particular focus on age and gender. Methods We identified all patients with a first AMI from 1997 to 2007 through linked hospital discharge and death records covering the Dutch population. Relative risks (RR of AMI incidence were estimated by mean equivalent household income at neighbourhood-level for strata of age and gender using Poisson regression models. Socioeconomic inequalities were also shown within the stratified age-gender groups by calculating the total number of events attributable to socioeconomic disadvantage. Results Between 1997 and 2007, 317,564 people had a first AMI. When comparing the most deprived socioeconomic quintile with the most affluent quintile, the overall RR for AMI was 1.34 (95 % confidence interval (CI: 1.32 – 1.36 in men and 1.44 (95 % CI: 1.42 – 1.47 in women. The socioeconomic gradient decreased with age. Relative socioeconomic inequalities were most apparent in men under 35 years and in women under 65 years. The largest number of events attributable to socioeconomic inequalities was found in men aged 45–74 years and in women aged 65–84 years. The total proportion of AMIs that was attributable to socioeconomic inequalities in the Dutch population of 1997 to 2007 was 14 % in men and 18 % in women. Conclusions Neighbourhood socioeconomic inequalities were observed in AMI incidence in the Netherlands, but the magnitude across age-gender groups depended on whether inequality was expressed in relative or absolute terms. Relative socioeconomic inequalities were high in young persons and women, where the absolute burden

  3. Incidence and risk factors of bleeding-related adverse events in patients with chronic lymphocytic leukemia treated with ibrutinib

    OpenAIRE

    Lipsky, Andrew H.; Farooqui, Mohammed Z.H.; Tian, Xin; Martyr, Sabrina; Cullinane, Ann M.; Nghiem, Khanh; Sun, Clare; Valdez, Janet; Niemann, Carsten U.; Herman, Sarah E. M.; Saba, Nakhle; Soto, Susan; Marti, Gerald; Uzel, Gulbu; Holland, Steve M.

    2015-01-01

    Ibrutinib is associated with bleeding-related adverse events of grade ≤2 in severity, and infrequently with grade ≥3 events. To investigate the mechanisms of bleeding and identify patients at risk, we prospectively assessed platelet function and coagulation factors in our investigator-initiated trial of single-agent ibrutinib for chronic lymphocytic leukemia. At a median follow-up of 24 months we recorded grade ≤2 bleeding-related adverse events in 55% of 85 patients. No grade ≥3 events occur...

  4. Multicenter study of trimethoprim/sulfamethoxazole-related hepatotoxicity: incidence and associated factors among HIV-infected patients treated for Pneumocystis jirovecii pneumonia.

    Directory of Open Access Journals (Sweden)

    Jen-Jia Yang

    Full Text Available The incidence of hepatotoxicity related to trimethoprim/sulfamethoxazole (TMP/SMX administered at a therapeutic dose may vary among study populations of different ethnicities and hepatotoxic metabolites of TMP/SMX may be decreased by drug-drug interaction with fluconazole. We aimed to investigate the incidence of hepatotoxicity and the role of concomitant use of fluconazole in HIV-infected patients receiving TMP/SMX for Pneumocystis jirovecii pneumonia. We reviewed medical records to collect clinical characteristics and laboratory data of HIV-infected patients who received TMP/SMX for treatment of P. jirovecii pneumonia at 6 hospitals around Taiwan between September 2009 and February 2013. Hepatotoxicity was defined as 2-fold or greater increase of aminotransferase or total bilirubin level from baselines. Roussel UCLAF Causality Assessment Method (RUCAM was used to analyze the causality of drug-induced liver injuries. NAT1 and NAT2 acetylator types were determined with the use of polymerase-chain-reaction (PCR restriction fragment length polymorphism to differentiate common single-nucleotide polymorphisms (SNPs predictive of the acetylator phenotypes in a subgroup of patients. During the study period, 286 courses of TMP/SMX treatment administered to 284 patients were analyzed. One hundred and fifty-two patients (53.1% developed hepatotoxicity, and TMP/SMX was considered causative in 47 (16.4% who had a RUCAM score of 6 or greater. In multivariate analysis, concomitant use of fluconazole for candidiasis was the only factor associated with reduced risk for hepatotoxicity (adjusted odds ratio, 0.372; 95% confidence interval, 0.145-0.957, while serostatus of hepatitis B or C virus, NAT1 and NAT2 acetylator types, or receipt of combination antiretroviral therapy was not. The incidence of hepatotoxicity decreased with an increasing daily dose of fluconazole up to 4.0 mg/kg. We conclude that the incidence of TMP/SMX-related hepatotoxicity was 16.4% in

  5. Multicenter study of trimethoprim/sulfamethoxazole-related hepatotoxicity: incidence and associated factors among HIV-infected patients treated for Pneumocystis jirovecii pneumonia.

    Science.gov (United States)

    Yang, Jen-Jia; Huang, Chung-Hao; Liu, Chun-Eng; Tang, Hung-Jen; Yang, Chia-Jui; Lee, Yi-Chien; Lee, Kuan-Yeh; Tsai, Mao-Song; Lin, Shu-Wen; Chen, Yen-Hsu; Lu, Po-Liang; Hung, Chien-Ching

    2014-01-01

    The incidence of hepatotoxicity related to trimethoprim/sulfamethoxazole (TMP/SMX) administered at a therapeutic dose may vary among study populations of different ethnicities and hepatotoxic metabolites of TMP/SMX may be decreased by drug-drug interaction with fluconazole. We aimed to investigate the incidence of hepatotoxicity and the role of concomitant use of fluconazole in HIV-infected patients receiving TMP/SMX for Pneumocystis jirovecii pneumonia. We reviewed medical records to collect clinical characteristics and laboratory data of HIV-infected patients who received TMP/SMX for treatment of P. jirovecii pneumonia at 6 hospitals around Taiwan between September 2009 and February 2013. Hepatotoxicity was defined as 2-fold or greater increase of aminotransferase or total bilirubin level from baselines. Roussel UCLAF Causality Assessment Method (RUCAM) was used to analyze the causality of drug-induced liver injuries. NAT1 and NAT2 acetylator types were determined with the use of polymerase-chain-reaction (PCR) restriction fragment length polymorphism to differentiate common single-nucleotide polymorphisms (SNPs) predictive of the acetylator phenotypes in a subgroup of patients. During the study period, 286 courses of TMP/SMX treatment administered to 284 patients were analyzed. One hundred and fifty-two patients (53.1%) developed hepatotoxicity, and TMP/SMX was considered causative in 47 (16.4%) who had a RUCAM score of 6 or greater. In multivariate analysis, concomitant use of fluconazole for candidiasis was the only factor associated with reduced risk for hepatotoxicity (adjusted odds ratio, 0.372; 95% confidence interval, 0.145-0.957), while serostatus of hepatitis B or C virus, NAT1 and NAT2 acetylator types, or receipt of combination antiretroviral therapy was not. The incidence of hepatotoxicity decreased with an increasing daily dose of fluconazole up to 4.0 mg/kg. We conclude that the incidence of TMP/SMX-related hepatotoxicity was 16.4% in HIV

  6. Cocaine-related admissions to an intensive care unit: a five-year study of incidence and outcomes.

    LENUS (Irish Health Repository)

    Galvin, S

    2010-02-01

    Cocaine misuse is increasing and it is evidently considered a relatively safe drug of abuse in Ireland. To address this perception, we reviewed the database of an 18-bed Dublin intensive care unit, covering all admissions from 2003 to 2007. We identified cocaine-related cases, measuring hospital mortality and long-term survival in early 2009. Cocaine-related admissions increased from around one annually in 2003-05 to 10 in 2007. Their median (IQR [range]) age was 25 (21-35 [17-47]) years and 78% were male. The median (IQR [range]) APACHE II score was 16 (11-27 [5-36]) and length of intensive care stay was 5 (3-9 [1-16]) days. Ten patients died during their hospital stay. A further five had died by the time of follow-up, a median of 24 months later. One was untraceable. Cocaine toxicity necessitating intensive care is increasingly common in Dublin. Hospital mortality in this series was 52%. These findings may help to inform public attitudes to cocaine.

  7. Subnormal Peripheral Blood Leukocyte Counts Are Related to the Lowest Prevalence and Incidence of Metabolic Syndrome: Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study

    Directory of Open Access Journals (Sweden)

    Shaomei Sun

    2014-01-01

    Full Text Available Few studies have assessed the relationship between a subnormal inflammatory status and metabolic syndrome (MS. We therefore designed a cross-sectional and 5-year cohort study to evaluate how a subnormal peripheral blood leukocyte count is related to MS. Participants were recruited from Tianjin Medical University General Hospital-Health Management Centre. Both a baseline cross-sectional (n=46,179 and a prospective assessment (n=13,061 were performed. Participants without a history of MS were followed up for 5 years. Leukocyte counts and MS components were assessed at baseline and yearly during the follow-up. Adjusted logistic and Cox proportional hazards regression models were used to assess relationships between the categories of leukocyte counts and MS. The subnormal leukocyte counts group (1,100–3,900 cells/mm3 had the lowest prevalence and incidence of MS. The odds ratio and hazard ratio (95% confidence interval of the highest leukocyte counts were 1.98 (1.57–2.49 and 1.50 (1.22–1.84 (both P for trend <0.0001, respectively, when compared to the subnormal leukocyte counts group after adjusting for potential confounders. This study has shown that subnormal leukocyte counts are independently related to the lowest prevalence and incidence of MS. The findings suggest that it is necessary to restudy and discuss the clinical or preventive value of subnormal leukocyte counts.

  8. Increased incidence rate of trauma and stressor related disorders in Denmark following the 9/11 attacks

    DEFF Research Database (Denmark)

    Hansen, Bertel Teilfeldt; Østergaard, Søren Dinesen; Sønderskov, Kim Mannemar;

    2016-01-01

    The 9/11 terrorist attacks in the United States had a profound impact on the physical and mental health of Americans, but effects beyond the US are largely unknown. To understand its wider aftermath we examined the consequences of 9/11 for mental disorders in the Kingdom of Denmark. With population...... in the etiology of trauma and stressor related disorders. The results indicate that the effects of 9/11 on mental disorders extended across the Atlantic to Denmark. Thus, the impact of terrorist attacks on mental health is likely not limited to inhabitants of the country under attack, but may also affect people...

  9. The What Works Clearinghouse: New Strategies to Support Non-Researchers in Using Rigorous Research in Education Decision-Making

    Science.gov (United States)

    Seftor, Neil; Monahan, Shannon; McCutcheon, AnnaMaria

    2016-01-01

    The What Works Clearinghouse (WWC) is a central and trusted source of information of scientific evidence for what works in education. Towards that end, the WWC summarizes research on a range of practices, programs, and policies (interventions) and disseminates that research in a variety of forms on the free public website. In recent years, the WWC…

  10. Age-Related Macular Degeneration and the Incidence of Cardiovascular Disease: A Systematic Review and Meta-Analysis

    Science.gov (United States)

    Wu, Juan; Uchino, Miki; Sastry, Srinivas M.; Schaumberg, Debra A.

    2014-01-01

    Importance Research has indicated some shared pathogenic mechanisms between age-related macular degeneration (AMD) and cardiovascular disease (CVD). However, results from prior epidemiologic studies have been inconsistent as to whether AMD is predictive of future CVD risk. Objective To systematically review population-based cohort studies of the association between AMD and risk of total CVD and CVD subtypes, coronary heart disease (CHD) and stroke. Data Sources A systematic search of the PubMed and EMBASE databases and reference lists of key retrieved articles up to December 20, 2012 without language restriction. Data Extraction Two reviewers independently extracted data on baseline AMD status, risk estimates of CVD and methods used to assess AMD and CVD. We pooled relative risks using random or fixed effects models as appropriate. Results Thirteen cohort studies (8 prospective and 5 retrospective studies) with a total of 1,593,390 participants with 155,500 CVD events (92,039 stroke and 62,737 CHD) were included in this meta-analysis. Among all studies, early AMD was associated with a 15% (95% CI, 1.08–1.22) increased risk of total CVD. The relative risk was similar but not significant for late AMD (RR, 1.17; 95% CI, 0.98–1.40). In analyses restricted to the subset of prospective studies, the risk associated with early AMD did not appreciably change; however, there was a marked 66% (95% CI, 1.31–2.10) increased risk of CVD among those with late AMD. Conclusion Whereas the results from all cohort studies suggest that both early and late AMD are predictive of a small increase in risk of future CVD, subgroup analyses limited to prospective studies demonstrate a markedly increased risk of CVD among people with late AMD. Retrospective studies using healthcare databases may have inherent methodological limitations that obscure such association. Additional prospective studies are needed to further elucidate the associations between AMD and specific CVD outcomes

  11. Using maya chair during the expulsive phase of delivery and its relation to the lower incidence of episiotomy or perineal tears

    Directory of Open Access Journals (Sweden)

    Laura López Quirós

    2014-04-01

    Full Text Available The aims of this article is to present the results obtained from the development of a clinical question about using maya obstetric chair during the expulsive phase of delivery and its relation to the lower incidence of episiotomy and perineal tears. In traditional cultures, the women give birth naturally in vertical positions as kneeling, standing, among others. In Western societies, physicians have influenced women will deliver in the supine position, sometimes with legs raised using stirrups. For women of our country is difficult to adopt "alternative" positions that have traditionally been seen as 'normal'. The maya chair is used in the countries of South America, and it appears to be an effective way to prevent perineal tears and the lower incidence of episiotomy duringchildbirth. To carry out this secondary research methodology for clinical practice based on evidence that consists of five steps was used. A question was developed in PICO format (patient, intervention, comparison and observation, then an information search was performed in different databases like Ebsco Host, Google Scholar, PubMed, Medline plus, Embase. 30 articles were found, were analyzed according to the criteria set FCL version 2.0, of which only one was close to answering the clinical question. Information was socialized in a formalpresentation by CIEBE-CR. It is conclude that there is insufficient evidence that the use of maya chair during theexpulsive phase of delivery significantly reduces the risk of perianal tear and lower incidence of episiotomy.

  12. Biopsy of the prostate guided by transrectal ultrasound: relation between warfarin use and incidence of bleeding complications

    Energy Technology Data Exchange (ETDEWEB)

    Ihezue, C.U. [Department of Radiology, Southampton General Hospital (United Kingdom); Smart, J. [Department of Radiology, Southampton General Hospital (United Kingdom); Dewbury, K.C. [Department of Radiology, Southampton General Hospital (United Kingdom)]. E-mail: keith.dewbury@suht.swest.nhs.uk; Mehta, R. [Department of Radiology, Southampton General Hospital (United Kingdom); Burgess, L. [Department of Radiology, Southampton General Hospital (United Kingdom)

    2005-04-01

    AIM: To determine the relation between warfarin use and the frequency of bleeding complications after biopsy of the prostate guided by transrectal ultrasound (TRUS). METHODS: Overall, 1022 consecutive patients with suspected prostatic disease were followed after biopsy. Warfarin and aspirin use was determined on the day of the procedure. A TRUS-guided biopsy was performed and patients were offered a questionnaire to complete 10 days after the procedure, to determine any immediate or delayed bleeding complications. Follow-up telephone calls were made to those who had not replied within the stipulated period. RESULTS: Of the 1000 patients who replied, 49 were receiving warfarin, 220 were receiving aspirin and 731 were not receiving any anticoagulant drugs. Of the 49 subjects reporting current use of warfarin, 18 (36.7%) experienced haematuria, compared with 440 (60.2%) of the patients receiving no anti-coagulant drugs who reported haematuria. This was statistically significant (p=0.001). Of the group receiving warfarin, 4 (8.2%) experienced haematospermia whereas 153 (21%) of the group receiving no anticoagulant medication reported haematospermia. This difference also was statistically significant (p=0.030). Rectal bleeding was experienced by 7 (14.3%) of the group receiving warfarin compared with 95 (13%) in the group without anticoagulant medication, but this was not statistically significant (p=0.80). We also demonstrated that there was no statistically significant association between the severity of the bleeding complications and medication with warfarin. CONCLUSION: None of the group receiving warfarin experienced clinically important bleeding complications. Our results suggest that the frequency and severity of bleeding complications were no worse in the warfarin group than in the control group and that discontinuing anticoagulation medication before prostate biopsy may be unnecessary.

  13. Experiments Relating to Whole-Body Activation Analysis in Man In Vivo Using 14-MeV Incident Neutrons

    International Nuclear Information System (INIS)

    Chromium eczema is a well-known phenomenon in dermatological practice. Different explanations may be given for it. According to one of these the specific texture of the skin of patients is assumed to allow more chromium to pass through the upper layers. As a result, the chromium accumulates faster in the dermis of patients so that a critical value is reached sooner. Another explanation might be that die sensitivity threshold for chromium in patients is lower than in normal persons and can more easily be exceeded. To distinguish between these possibilities and to obtain more information, an investigation was started in which the chromium content in the skin was compared for eczema patients and normal people. The sample weight (10 mg) and the chromium content (0.2 - 0.4 ppm) involved require a sensitive technique. Neutron activation analysis is well suited to this purpose. Under our operation conditions (irradiation time 10 days, neutron flux 1014n/cm2s) it is possible to determine quantities as low as 5 x 1011 g of chromium. Preliminary experiments show relatively large variations in chromium content of comparable samples, even in skin samples taken from the back of a single person. It is further suggested by the results of these experiments that the chromium content in the skin of eczema patients is lower than in that of normal patients. The results of the analysis may be seriously affected by chromium contamination during sample preparation. Therefore chromium-free instruments must be used. To avoid chromium migration in the skin due to degeneration processes, samples must be taken from persons alive or shortly after their death. (author)

  14. Estimated incidence of cardiovascular complications related to type 2 diabetes in Mexico using the UKPDS outcome model and a population-based survey

    Directory of Open Access Journals (Sweden)

    Aguilar-Salinas Carlos A

    2011-01-01

    Full Text Available Abstract Background To estimate the incidence of complications, life expectancy and diabetes related mortality in the Mexican diabetic population over the next two decades using data from a nation-wide, population based survey and the United Kingdom Prospective Diabetes Study (UKPDS outcome model Methods The cohort included all patients with type 2 diabetes evaluated during the National Health and Nutrition Survey (ENSANut 2006. ENSANut is a probabilistic multistage stratified survey whose aim was to measure the prevalence of chronic diseases. A total of 47,152 households were visited. Results are shown stratified by gender, time since diagnosis (> or ≤ to 10 years and age at the time of diagnosis (> or ≤ 40 years. Results The prevalence of diabetes in our cohort was 14.4%. The predicted 20 year-incidence for chronic complications per 1000 individuals are: ischemic heart disease 112, myocardial infarction 260, heart failure 113, stroke 101, and amputation 62. Furthermore, 539 per 1000 patients will have a diabetes-related premature death. The average life expectancy for the diabetic population is 10.9 years (95%CI 10.7-11.2; this decreases to 8.3 years after adjusting for quality of life (CI95% 8.1-8.5. Male sex and cases diagnosed after age 40 have the highest risk for developing at least one major complication during the next 20 years. Conclusions Based on the current clinical profile of Mexican patients with diabetes, the burden of disease related complications will be tremendous over the next two decades.

  15. Medication incidents reported to an online incident reporting system.

    LENUS (Irish Health Repository)

    Alrwisan, Adel

    2011-01-15

    AIMS: Approximately 20% of deaths from adverse events are related to medication incidents, costing the NHS an additional £500 million annually. Less than 5% of adverse events are reported. This study aims to assess the reporting rate of medication incidents in NHS facilities in the north east of Scotland, and to describe the types and outcomes of reported incidents among different services. Furthermore, we wished to quantify the proportion of reported incidents according to the reporters\\' profession. METHODS: A retrospective description was made of medication incidents reported to an online reporting system (DATIX) over a 46-month-period (July 2005 to April 2009). Reports originated from acute and community hospitals, mental health, and primary care facilities. RESULTS: Over the study period there were 2,666 incidents reported with a mean monthly reporting rate of 78.2\\/month (SD±16.9). 6.1% of all incidents resulted in harm, with insulin being the most commonly implicated medication. Nearly three-quarters (74.2%, n=1,978) of total incidents originated from acute hospitals. Administration incidents were implicated in the majority of the reported medication incidents (59%), followed by prescribing (10.8%) and dispensing (9.9%), while the nondescript "other medication incidents" accounted for 20.3% of total incidents. The majority of reports were made by nursing and midwifery staff (80%), with medical and dental professionals reporting the lowest number of incidents (n=56, 2%). CONCLUSIONS: The majority of medication incidents in this study were reported by nursing and midwifery staff, and were due to administration incidents. There is a clear need to elucidate the reasons for the limited contribution of the medical and dental professionals to reporting medication incidents.

  16. Incidence and related factors of dysphagia in stroke patients%脑卒中患者摄食-吞咽障碍的发病及相关因素

    Institute of Scientific and Technical Information of China (English)

    李红玲; 王志红; 吴冰洁; 张彤; 张玉淼

    2003-01-01

    AIM: To investigate the incidence and related factors of dysphagia in strokepatients. METHODS: Water drinking test were applied to 100 patients whoreceived continuously by neurology and rehabilitation department after theircondition was stable. RESULTS: Dysphagia incidence of the 100 cases ofstroke patients was 33%. CONCLUSION: Analysis of related factors indi-cates that incidence of dysphagia has no relationship with sex, age, position ofthe lesion and complications, but shows correlation with status of conscious-ness, cognitive skill, character of the lesion, position, course, exercise abili-ty, daily life activities, buccofacial apraxia, speech apraxia and aphasia.

  17. Interaction between Obesity and the NFKB1 - 94ins/delATTG Promoter Polymorphism in Relation to Incident Acute Coronary Syndrome

    DEFF Research Database (Denmark)

    Stegger, Jakob Gerhard; Schmidt, Erik Berg; Berentzen, Tina Landsvig;

    2013-01-01

    The NF-κB transcription factor family regulates several genes encoding pro-inflammatory and anti-inflammatory proteins in adipose tissues and in atherosclerotic plaques. The deletion variant allele of the NFKB1 - 94ins/delATTG promoter polymorphism leads to lower transcript levels of the p50 subu...... polymorphism and general, abdominal, and gluteofemoral obesity in relation to the risk of incident acute coronary syndrome (ACS) in three large independent cohorts.......The NF-κB transcription factor family regulates several genes encoding pro-inflammatory and anti-inflammatory proteins in adipose tissues and in atherosclerotic plaques. The deletion variant allele of the NFKB1 - 94ins/delATTG promoter polymorphism leads to lower transcript levels of the p50...

  18. Cyclopia: An Epidemiologic Study in a Large Dataset From the International Clearinghouse of Birth Defects Surveillance and Research

    Science.gov (United States)

    Orioli, Iêda M.; Amar, Emmanuelle; Bakker, Marian K.; Bermejo-Sánchez, Eva; Bianchi, Fabrizio; Canfield, Mark A.; Clementi, Maurizio; Correa, Adolfo; Csáky-Szunyogh, Melinda; Feldkamp, Marcia L.; Landau, Danielle; Leoncini, Emanuele; Li, Zhu; Lowry, R. Brian; Mastroiacovo, Pierpaolo; Morgan, Margery; Mutchinick, Osvaldo M.; Rissmann, Anke; Ritvanen, Annukka; Scarano, Gioacchino; Szabova, Elena; Castilla, Eduardo E.

    2015-01-01

    Cyclopia is characterized by the presence of a single eye, with varying degrees of doubling of the intrinsic ocular structures, located in the middle of the face. It is the severest facial expression of the holoprosencephaly (HPE) spectrum. This study describes the prevalence, associated malformations, and maternal characteristics among cases with cyclopia. Data originated in 20 Clearinghouse (ICBDSR) affiliated birth defect surveillance systems, reported according to a single pre-established protocol. A total of 257 infants with cyclopia were identified. Overall prevalence was 1 in 100,000 births (95%CI: 0.89–1.14), with only one program being out of range. Across sites, there was no correlation between cyclopia prevalence and number of births (r = 0.08; P=0.75) or proportion of elective termination of pregnancy (r= −0.01; P=0.97). The higher prevalence of cyclopia among older mothers (older than 34) was not statistically significant. The majority of cases were liveborn (122/200; 61%) and females predominated (male/total: 42%). A substantial proportion of cyclopias (31%) were caused by chromosomal anomalies, mainly trisomy 13. Another 31% of the cases of cyclopias were associated with defects not typically related to HPE, with more hydrocephalus, heterotaxia defects, neural tube defects, and preaxial reduction defects than the chromosomal group, suggesting the presence of ciliopathies or other unrecognized syndromes. Cyclopia is a very rare defect without much variability in prevalence by geographic location. The heterogeneous etiology with a high prevalence of chromosomal abnormalities, and female predominance in HPE, were confirmed, but no effect of increased maternal age or association with twinning was observed. PMID:22006661

  19. Distribution of illegal incident characteristics: cases of bank fraud and embezzlement, computer-related crime, and insider theft from drug manufacturers and distributors

    Energy Technology Data Exchange (ETDEWEB)

    Heineke, J M

    1979-10-01

    Three data sets were used to estimate joint and conditional probability distributions between various variables of interest in bank fraud and embezzlement (BF and E) cases of $10,000 dollars or more, computer-related crime cases of various types, and cases of insider theft from drug manufacturers and distributors. This report describes in tabular form the information contained in the three rather extensive data sets from industries facing insider threats which, in one or more dimensions, are analogous to insider threats potentially confronting managers in the nuclear industry. The data in Tables 1 through 29 were computed from the 313 cases of bank fraud and embezzlement (BF and E) representing losses of $10,000 or more reported to the Federal Deposit Insurance Corporation (FDIC) for the period 1977 to 1978. The data in Tables 30 through 64 were computed from the 461 cases of computer-related crime obtained from SRI International for the period 1958 to 1978. These incidents include inventory manipulations designed to hide errors, phony entries used to cover embezzlements, schemes used to penetrate a system and surreptitiously bring about a system crash, and sabotage. The data in Tables 65 through 67 were computed from data reported by the Drug Enforcement Agency (DEA) for the period 1973 to 1978. These data, though limited, provided several interesting insights into the insider-threat problem.

  20. Analysis of incidence of keratoconus in relatives of patients who underwent corneal transplant due to advanced keratoconus using the Orbscan II topographic graphs

    Science.gov (United States)

    López Olazagasti, Estela; Hernández y del Callejo, César E.; Ibarra-Galitzia, Jorge; Ramírez-Zavaleta, Gustavo; Tepichín, Eduardo

    2011-10-01

    Keratoconus is a corneal disease in which the cornea assumes a conical shape due to an irregular alteration of the internal structure of the corneal tissue and sometimes is progressive, especially in young people. Anatomically, the main signs of keratoconus are thinning of the cornea in its central or paracentral region, usually accompanied by an increase in this part of a high irregular astigmatism, with a consequent loss of vision. Its diagnosis requires a thorough study including the family history, a complete ophthalmologic examination and imaging studies. This diagnosis allows classifying the type of keratoconus, which allow determining options of management, with what it is possible to establish a visual prognosis of each eye. One of the indicators that help in the diagnosis of keratoconus is an inherited familiar propensity. The literature reports an incidence of keratoconus of 11%1 in first-degree relatives of patients with keratoconus. Results suggest an ethnic dependence, which implies that the knowledge of the tendency of keratoconus in the Mexican population is important. In this work, we present the preliminary results of the study realized to a group of relatives of patients who underwent corneal transplant by advanced keratoconus using Orbscan II topographic diagnosis, to determine the predisposition to Keratoconus in this group.e

  1. INIS strategic planning and INIS Clearinghouse document delivery: from four weeks to four minutes

    International Nuclear Information System (INIS)

    I joined INIS in May 1994 as a consultant to create a Strategic Plan for 1995–2000. I had left a US Department of Justice contractor, Aspen Corporation, which operated the National Criminal Justice Reference Service (NCJRS), as chief of two libraries and manager of a clearinghouse for the world’s criminal justice literature. NCJRS collected this literature, created a bibliographic on-line database and converted non-copyrighted literature to microfiche. The government contract had to be renewed every five years and the Aspen proposal was basically a five year strategic plan, to which I contributed. Thus, when I came to INIS, I had an understanding of the process. The next six months were devoted to preparing STRATEGIC GUIDELINES FOR INIS DEVELOPMENTS 1995–2000 with the caveat: Notice: The guidelines proposed in this report are those of the Information Consultant. They represent a wide range of options that are being presented for further refinement by Peer Reviewers, INIS Consultants and finally the Advisory Committee for INIS. Forwarding of these guidelines does not represent concurrence or nonconcurrence by the INIS Secretariat. 30 September 1994. Member States are now collecting and submitting most of their NCL in electronic format. It is sent to INIS for quality control and consolidation. Consequently, INIS staff has been gradually reduced. The amount of NCL disseminated has remained constant, and an ongoing process to digitize the entire INIS collection on microfiche will be completed in 2016, a process I started in 1999. Before leaving INIS in 1999, I realized that the future would provide a reduced requirement for INIS imaging and recommended the Clearinghouse become a resource for all of the IAEA. Today it serves that purpose

  2. Incidence and risk factors of HIV-related non-Hodgkin's lymphoma in the era of combination antiretroviral therapy: a European multicohort study

    DEFF Research Database (Denmark)

    Bohlius, Julia; Schmidlin, Kurt; Costagliola, Dominique;

    2009-01-01

    Incidence and risk factors of HIV-associated non-Hodgkin's lymphoma (NHL) are not well defined in the era of combination antiretroviral therapy (cART).......Incidence and risk factors of HIV-associated non-Hodgkin's lymphoma (NHL) are not well defined in the era of combination antiretroviral therapy (cART)....

  3. Self-reported whole-grain intake and plasma alkylresorcinol concentrations in combination in relation to the incidence of colorectal cancer

    DEFF Research Database (Denmark)

    Knudsen, Markus Dines; Kyrø, Cecilie; Olsen, Anja;

    2014-01-01

    Self-reported food frequency questionnaires (FFQs) have occasionally been used to investigate the association between whole-grain intake and the incidence of colorectal cancer, but the results from those studies have been inconsistent. We investigated this association using intakes of whole grains......-grain consumption (HELGA, 1992-1998). Incidence rate ratios and 95% confidence intervals were calculated using conditional logistic regression. Plasma alkylresorcinol concentrations alone and Howe's score with ranks were inversely associated with the incidence of distal colon cancer when the highest quartile...... was compared with the lowest (for alkylresorcinol concentrations, incidence rate ratio = 0.34, 95% confidence interval: 0.13, 0.92; for Howe's score with ranks, incidence rate ratio = 0.35, 95% confidence interval: 0.15, 0.86). No association was observed between whole-grain intake and any colorectal cancer...

  4. Remarkable change in age-specific breast cancer incidence in the Swiss canton of Geneva and its possible relation with the use of hormone replacement therapy

    International Nuclear Information System (INIS)

    This article aims to explain the reasons for the remarkable change in age of breast cancer occurrence in the Swiss canton of Geneva. We used population-based data from the Geneva cancer registry, which collects information on method of detection, stage and tumour characteristics since 1975. For patients diagnosed between 1997–2003, we obtained additional information on use of hormone replacement therapy from a large prospective study on breast cancer. Using generalized log linear regression analysis, we compared age-specific incidence rates with respect to period, stage, oestrogen receptor status, method of detection and use of hormone replacement therapy. In the periods 1975–1979 and 1985–1989, breast cancer risk increased with age, showing the highest incidence rates among women aged ≥ 85 years. From 1997, the age-specific incidence curve changed completely (p < 0.0001), showing an incidence peak at 60–64 years and a reduced incidence among elderly women. This incidence peak concerned mainly early stage and oestrogen positive cancers and was exclusively observed among women who ever used hormone replacement therapy, regardless whether the tumour was screen-detected or not. The increasing prevalence of hormone replacement therapy use during the 1990s could explain the important change in age-specific breast cancer incidence, not only by increasing breast cancer risk, but also by revealing breast cancer at an earlier age

  5. Spatial-Temporal Hotspot Pattern Analysis of Provincial Environmental Pollution Incidents and Related Regional Sustainable Management in China in the Period 1995–2012

    Directory of Open Access Journals (Sweden)

    Lei Ding

    2015-10-01

    Full Text Available Spatial-temporal hotspot pattern analysis of environmental pollution incidents provides an indispensable source of information for the further development of incident prevention measures. In this study, the spatial-temporal patterns of environmental pollution incidents in China in the period of 1995–2012 were analyzed, using the Spatial Getis-Ord statistic and an Improved Prediction Accuracy Index (IAPI. The results show that, in this period, the occurrence of environmental incidents exhibited a dynamic growth pattern but then dropped and continued to drop after the year 2006, which was considered a crucial turning point. Not coincidentally, this corresponds to the year when the State Council issued its National Environmental Emergency Plan, and following the examination of major incidents, special actions were taken to strengthen the control of incidents and emergency responses. The results from Getis-Ord General G statistical analysis show that the spatial agglomeration phenomenon was statistically significant after 1999 and that the level of spatial agglomeration was rising, while the Getis-Ord Gi* statistical analysis reveals that environmental pollution incidents were mainly agglomerated in the Pan Yangtze River Delta and Pan Pearl River Delta regions. Accordingly, the spatial-temporal hotspot pattern based on the IAPI values at the provincial scale could be categorized into: stable hotspots, unstable hotspots, and cold-spot areas. The stable hotspots category was further divided into three subtypes: industrial distribution type, industrial transfer type, and extensive economic growth type. Finally, the corresponding measures for sustainable management were proposed: stable hotspots were classified as essential regions requiring the immediate prevention and control of environmental pollution incidents; unstable hotspots were characterized by their need for ongoing and continual prevention measures, and cold-spots were those areas that

  6. γ-Hydroxybutyrate: experience of 9 years of γ-hydroxybutyrate (GHB)-related incidents during rave parties in The Netherlands.

    Science.gov (United States)

    Krul, Jan; Girbes, Armand R J

    2011-04-01

    OBJECTIVE. The objective of this study was to determine the health disturbances and to assess the severity of the incidents as reported during a 9-year experience of gamma-hydroxybutyrate (GHB)-related First Aid Attendees attending First Aid Stations at rave parties. DESIGN. This study was a prospective observational study of self-referred patients from the year 2000 to 2008. During rave parties, First Aid Stations were staffed with specifically trained medical and paramedical personnel. Patients were diagnosed and treated, and data were recorded using standardized methods. RESULTS. During a 9-year period with 202 rave parties, involving approximately three million visitors, 22 604 First Aid Attendees visited the First Aid Stations, of which 771 reported GHB-related health problems. The mean age of the GHB-using First Aid Attendees was 25.7 ± 6.1 years, most of them (66.4%) were male. Approximately one-third (32.7%) of them used one substance, while 48.1% combined GHB with ecstasy, alcohol, or cannabis. One of five (19.2%) combined GHB with other substances or more than one substance. One case was categorized as severe/life-threatening and 202 (26.2%) cases as moderate, requiring further medical care. In total, 43 (5.6%) First Aid Attendees needed hospital care. The most encountered health disturbance was altered consciousness. Combinations of altered consciousness, vomiting, and/or low body temperature were found in 186 cases (24.1%) and considered to be potentially dangerous. GHB-related First Aid Attendees required a longer stay at the First Aid Stations than the total group First Aid Attendees did (median 45 min vs 10 min). CONCLUSION. We found very little, severe short-term GHB-related health disturbances during rave parties in The Netherlands. Hospital referrals were rare. The most found symptom was altered consciousness, sometimes accompanied by vomiting and low body temperature. At events where the visitors use GHB, a well-trained and qualified

  7. A prospective study to determine the circumstances, incidence and outcome of cardiopulmonary resuscitation in a referral hospital in India, in relation to various factors

    Directory of Open Access Journals (Sweden)

    Muralidhar Joshi

    2015-01-01

    Full Text Available Background and Aims: Cardiac arrest has multifactorial aetiology and the outcome depends on timely and correct interventions. We decided to investigate the circumstances, incidence and outcome of cardiopulmonary resuscitation (CPR at a tertiary hospital in India, in relation to various factors, including extensive basic life support and advanced cardiac life support training programme for all nurses and doctors. Methods: It has been over a decade and a half with periodical updates and implementation of newer guidelines prepared by various societies across the world about CPR for both in-hospital and out-of hospital cardiac arrests (IHCA and OHCA. We conducted a prospective study wherein all cardiac arrests reported in the hospital consecutively for 12 months were registered for the study and followed their survival up to 1-year. Statistical analysis was performed by using Chi-square test for significant differences in proportions applied to various parameters of the study. Results: The main outcome measures were; (following CPR return of spontaneous circulation, survival for 24 h, survival from 24 h to 6 weeks or discharge, alive at 1-year. For survivors, an assessment was made about their cerebral performance and overall performance and accordingly graded. All these data were tabulated. Totally 419 arrests were reported in the hospital, out of which 413 were in-hospital arrests. Out of this 260 patients were considered for resuscitation, we had about 27 survivors at the end of 1-year follow-up (10.38%. Conclusion: We conclude by saying there are many factors involved in good clinical outcomes following IHCAs and these variable factors need to be researched further.

  8. Mining User spatiotemporal Behavior in Geospatial Cyberinfrastructure --using GEOSS Clearinghouse as an example

    Science.gov (United States)

    XIA, J.; Yang, C.; Liu, K.; Huang, Q.; Li, Z.

    2013-12-01

    Big Data becomes increasingly important in almost all scientific domains, especially in geoscience where hundreds to millions of sensors are collecting data of the Earth continuously (Whitehouse News 2012). With the explosive growth of data, various Geospatial Cyberinfrastructure (GCI) (Yang et al. 2010) components are developed to manage geospatial resources and provide data access for the public. These GCIs are accessed by different users intensively on a daily basis. However, little research has been done to analyze the spatiotemporal patterns of user behavior, which could be critical to the management of Big Data and the operation of GCIs (Yang et al. 2011). For example, the spatiotemporal distribution of end users helps us better arrange and locate GCI computing facilities. A better indexing and caching mechanism could be developed based on the spatiotemporal pattern of user queries. In this paper, we use GEOSS Clearinghouse as an example to investigate spatiotemporal patterns of user behavior in GCIs. The investigation results show that user behaviors are heterogeneous but with patterns across space and time. Identified patterns include (1) the high access frequency regions; (2) local interests; (3) periodical accesses and rush hours; (4) spiking access. Based on identified patterns, this presentation reports several solutions to better support the operation of the GEOSS Clearinghouse and other GCIs. Keywords: Big Data, EarthCube, CyberGIS, Spatiotemporal Thinking and Computing, Data Mining, User Behavior Reference: Fayyad, U. M., Piatetsky-Shapiro, G., Smyth, P., & Uthurusamy, R. 1996. Advances in knowledge discovery and data mining. Whitehouse. 2012. Obama administration unveils 'BIG DATA' initiative: announces $200 million in new R&D investments. Whitehouse. Retrieved from http://www.whitehouse.gov/sites/default/files/microsites/ostp/big_data_press_release_final_2.pdf [Accessed 14 June 2013] Yang, C., Wu, H., Huang, Q., Li, Z., & Li, J. 2011. Using spatial

  9. Analysis of the Relation Between Exposure to Ionising Radiation from Computed Tomography Scans in Childhood and Cancer Incidence within the 'Cohorte Enfant Scanner' Study

    International Nuclear Information System (INIS)

    central nervous system, breast cancer, thyroid cancer or leukaemia ranging from 0.01 per thousand to 5 per thousand. Cancer risks may be up to 7 times higher for patients aged 1 year compared to 10 year olds. Uncertainties attached to these risk predictions were quantified by simulations. From the follow-up of cancer incidence in the cohort, the dose-response relation was studied between the risk of tumors of the central nervous system, leukaemia and lymphoma, and cumulative X-ray doses to the organs of interest from CT scans. No significant increased risk was observed. Indeed, in 2011, the duration of the follow-up, i.e. 4 years on average, was very short. The analyzes have nevertheless characterized the impact of (acquired or hereditary) immunodeficiencies and other genetic factors predisposing to cancer on the risk estimates, and highlighted the importance of considering the indication of examinations in studies on CT scans. The follow-up of the cohort should be extended to provide more robust risk estimates. Extension of this study as well as expected results from other cohorts, particularly within the Epi-CT project, would provide, in the next 5 years, significant progresses on the issue of the potential adverse effects of CT. To date, risk predictions from quantitative risk assessment are still uncertain, especially for cerebral tumours, but should help to guide the use of CT. In addition, efforts for optimizing the radiological procedures are still needed to reduce the doses delivered in paediatrics and the potential associated risks. (author)

  10. Quality incidents in projects

    OpenAIRE

    Eren, Serkan

    2010-01-01

    A quality incident is an occurrence that has a negative consequence on time, cost and quality.These incidents are important for quality management in the projects. Similar to Health,Safety and Environment Incidents (HSE incidents) which are widely used in organizations allaround the world and in their projects, quality incidents should also be reported. For thepurpose of this, quality incident reporting systems can be used.The main purpose of this project is to define and explain the current ...

  11. Scrutinizing incident reporting in anaesthesia: why is an incident perceived as critical?

    DEFF Research Database (Denmark)

    Maaløe, R; la Cour, M; Hansen, A;

    2006-01-01

    The purpose of the present study was to measure the incidence and type of incidents that occurred in relation to anaesthesia and surgery during a 1-year period in six Danish hospitals. Furthermore, we wanted to identify risk factors for incidents, as well as risk factors for incidents being deemed...

  12. The Duchenne muscular dystrophy population i Denmark, 1977-2001: prevalence, incidence and survival in relation to the introduction of ventilator use

    DEFF Research Database (Denmark)

    2003-01-01

    Mechanical ventilation of patients with Duchenne muscular dystrophy continues to be a subject of study. The purpose was to estimate prevalence, incidence, mortality and use of mechanical ventilation in the total Duchenne muscular dystrophy population in Denmark between 1977 and 2001 and further, to....... While overall incidence remained stable at 2.0 per 105, prevalence rose from 3.1 to 5.5 per 105, mortality fell from 4.7 to 2.6 per 100 years at risk and prevalence of Duchenne muscular dystrophy ventilator users rose from 0.9 to 43.4 per 100. We conclude that survival of Duchenne muscular dystrophy...

  13. Relation of the weather and the lunar cycle with the incidence of trauma in the Groningen region over a 36-year period

    NARCIS (Netherlands)

    Stomp, W.; Fidler, V.; ten Duis, H.J.; Nijsten, M.W.

    2009-01-01

    Background: The time distribution of injuries is not random. To assess the potential impact of weather and the phase of the moon on accidents, adjustment for known periodic and nonperiodic factors may be important. We compared the incidence of injuries with quantitative and qualitative weather varia

  14. Convergence of decreasing male and increasing female incidence rates in major tobacco-related cancers in Europe in 1988-2010

    NARCIS (Netherlands)

    J. Lortet-Tieulent (J.); E. Renteria (Elisenda); L. Sharp; E. Weiderpass (Elisabete); H. Comber; P. Baas (Paul); F. Bray (Freddie); J.W.W. Coebergh (Jan Willem); I. Soerjomataram (Isabelle)

    2013-01-01

    textabstractIntroduction: Smoking prevalence has been declining in men all over Europe, while the trend varies in European regions among women. To study the impact of past smoking prevalence, we present a comprehensive overview of the most recent trends in incidence, during 1988-2010, in 26 countrie

  15. Falls incidence underestimates the risk of fall-related injuries in older age groups : a comparison with the FARE (Falls risk by Exposure)

    NARCIS (Netherlands)

    Etman, Astrid; Wijlhuizen, Gert Jan; van Heuvelen, Marieke J. G.; Chorus, Astrid; Hopman-Rock, Marijke

    2012-01-01

    Background: up till now, the risk of falls has been expressed as falls incidence (i.e. the number of falls or fallers per 100 person-years). However, the risk of an accident or injury is the probability of having an accident or injury per unit of exposure. The FARE ( Falls risk by Exposure) is a mea

  16. Falls incidence underestimates the risk of fall-related injuries in older age groups: A comparison with the FARE (Falls risk by exposure)

    NARCIS (Netherlands)

    Etman, A.; Wijlhuizen, G.J.; Heuvelen, M.J.G. van; Chorus, A.; Hopman-Rock, M.

    2012-01-01

    Background: up till now, the risk of falls has been expressed as falls incidence (i.e. the number of falls or fallers per 100 person-years). However, the risk of an accident or injury is the probability of having an accident or injury per unit of exposure. The FARE (Falls risk by Exposure) is a meas

  17. Clearinghouse-type system and database for post‑seismic buildings assessment

    Directory of Open Access Journals (Sweden)

    Claudiu-Sorin DRAGOMIR

    2015-07-01

    Full Text Available The paper presents the outline and function of a system for field assessment and the structure of a database for post-earthquake inspections, to be used with the Romanian Methodology for rapid buildings assessment, indicative ME003/2007, and for other research purposes. Functioning mode of the system for assessment in emergencies caused by earthquakes and the structure of the data collected by the field teams that participated in post-earthquake inspection are presented in this paper. A system for interdisciplinary assessment was taken into account for strong Vrancea intermediate earthquakes, but it will be useful also for crustal earthquakes of local or regional extent. The proposed system envisages a coordination centre and a clearinghouse at Bucharest, in NIRD “URBAN-INCERC” that coordinates branches of the territory (Iaşi, Timişoara and Cluj Napoca. Given the large area affected by Vrancea earthquakes, the system will pursue the establishment of regional centers also in the cities of Braşov and Constanţa, where there are universities in the field. To demonstrate the relevance of the system, the paper presents a case study of two buildings located in Bucharest downtown. By exploiting a software application created at INCERC Bucharest Branch, numerical values and charts can be obtained for all buildings investigated by the INCERC inspectors.

  18. Earthspace: A National Clearinghouse For Higher Education In Space And Earth Sciences

    Science.gov (United States)

    CoBabe-Ammann, Emily; Shipp, S.; Dalton, H.

    2012-10-01

    The EarthSpace is a searchable database of undergraduate classroom materials for undergraduate faculty teaching earth and space sciences at both the introductory and upper division levels. Modeled after the highly successful SERC clearinghouse for geosciences assets, EarthSpace was designed for easy submission of classroom assets - from homeworks and computerinteractives to laboratories and demonstrations. All materials are reviewedbefore posting, and authors adhere to the Creative Commons Non-Commercial Attribution (CC-BY NC 3.0). If authors wish, their EarthSpace materials are automatically cross-posted to other digital libraries (e.g., ComPADRE) and virtual higher education communities(e.g., Connexions). As new electronic repositories come online, EarthSpace materials will automatically be sent. So faculty submit their materials only once and EarthSpace ensures continual distribution as time goes on and new opportunities arise. In addition to classroom materials, EarthSpace provides news and information about educational research and best practices, funding opportunities, and ongoing efforts and collaborations for undergraduate education. http://www.lpi.usra.edu/earthspace

  19. Oral Administration of Faecalibacterium prausnitzii Decreased the Incidence of Severe Diarrhea and Related Mortality Rate and Increased Weight Gain in Preweaned Dairy Heifers

    Science.gov (United States)

    Foditsch, Carla; Pereira, Richard Van Vleck; Ganda, Erika Korzune; Gomez, Marilia Souza; Marques, Eduardo Carvalho; Santin, Thiago; Bicalho, Rodrigo Carvalho

    2015-01-01

    Probiotics are a promising alternative to improve food animal productivity and health. However, scientific evidence that specific microbes can be used to benefit animal health and performance is limited. The objective of this study was to evaluate the effects of administering a live culture of Faecalibacterium prausnitzii to newborn dairy calves on subsequent growth, health, and fecal microbiome. Initially, a safety trial was conducted using 30 newborn bull calves to assess potential adverse effects of the oral and rectal administration of F. prausnitzii to neonatal calves. No adverse reactions, such as increased body temperature or heart and respiratory rates, were observed after the administration of the treatments. All calves survived the experimental period, and there was no difference in fecal consistency score, attitude, appetite or dehydration between the treatment groups. The rectal route was not an efficient practice while the oral route ensures that the full dose is administered to the treated calves. Subsequently, a randomized field trial was completed in a commercial farm with preweaned calves. A total of 554 Holstein heifers were assigned to one of two treatment groups: treated calves (FPTRT) and non-treated calves (control). Treated calves received two oral doses of F. prausnitzii, one at treatment assignment (1st week) and another one week later. The FPTRT group presented significantly lower incidence of severe diarrhea (3.1%) compared with the control group (6.8%). Treated calves also had lower mortality rate associated with severe diarrhea (1.5%) compared to control calves (4.4%). Furthermore, FPTRT calves gained significantly more weight, 4.4 kg over the preweaning period, than controls calves. The relative abundance of F. prausnitzii in the fecal microbiota was significantly higher in the 3rd and 5th weeks of life of FPTRT calves than of the control calves, as revealed by sequencing of the 16S rRNA gene. Our findings showed that oral

  20. Oral Administration of Faecalibacterium prausnitzii Decreased the Incidence of Severe Diarrhea and Related Mortality Rate and Increased Weight Gain in Preweaned Dairy Heifers.

    Directory of Open Access Journals (Sweden)

    Carla Foditsch

    Full Text Available Probiotics are a promising alternative to improve food animal productivity and health. However, scientific evidence that specific microbes can be used to benefit animal health and performance is limited. The objective of this study was to evaluate the effects of administering a live culture of Faecalibacterium prausnitzii to newborn dairy calves on subsequent growth, health, and fecal microbiome. Initially, a safety trial was conducted using 30 newborn bull calves to assess potential adverse effects of the oral and rectal administration of F. prausnitzii to neonatal calves. No adverse reactions, such as increased body temperature or heart and respiratory rates, were observed after the administration of the treatments. All calves survived the experimental period, and there was no difference in fecal consistency score, attitude, appetite or dehydration between the treatment groups. The rectal route was not an efficient practice while the oral route ensures that the full dose is administered to the treated calves. Subsequently, a randomized field trial was completed in a commercial farm with preweaned calves. A total of 554 Holstein heifers were assigned to one of two treatment groups: treated calves (FPTRT and non-treated calves (control. Treated calves received two oral doses of F. prausnitzii, one at treatment assignment (1st week and another one week later. The FPTRT group presented significantly lower incidence of severe diarrhea (3.1% compared with the control group (6.8%. Treated calves also had lower mortality rate associated with severe diarrhea (1.5% compared to control calves (4.4%. Furthermore, FPTRT calves gained significantly more weight, 4.4 kg over the preweaning period, than controls calves. The relative abundance of F. prausnitzii in the fecal microbiota was significantly higher in the 3rd and 5th weeks of life of FPTRT calves than of the control calves, as revealed by sequencing of the 16S rRNA gene. Our findings showed that oral

  1. Risk of Malignant Neoplasm in Patients with Incident Rheumatoid Arthritis 1980-2007 in relation to a Comparator Cohort: A Population-Based Study.

    Science.gov (United States)

    Raheel, Shafay; Crowson, Cynthia S; Wright, Kerry; Matteson, Eric L

    2016-01-01

    Objective. To determine whether the incidence of malignancy is increased in patients with rheumatoid arthritis (RA) compared to a matched comparison cohort and to identify risk for any individual malignancy in RA. Methods. A cohort of 813 Olmsted County, Minnesota, residents who first fulfilled 1987 ACR criteria for RA in 1980-2007 was previously identified by medical record review. Medical records of 813 RA cases and a comparison cohort of age and sex matched Olmsted County residents without RA were evaluated retrospectively for cancer occurrence. Patients in both cohorts were followed until death, migration from Olmsted County, or 12/31/2014. Results. The RA and non-RA cohorts (mean age at incidence/index date: 55.9 [SD: 15.7] years; 68.4% females in both cohorts) were followed on average of 14.1 (SD: 7.7) and 14.9 (SD: 8.1) years, respectively. Prior to RA incidence/index date, 52 RA patients and 66 non-RA subjects had malignancies excluding NMSC (p = 0.21). During follow-up, significantly more malignancies occurred in patients with RA (n = 143) than in comparator subjects (n = 118; hazard ratio: 1.32; p = 0.027). Inclusion of NMSC obviated this difference. Conclusion. After excluding NMSC, there was a small to moderately increased risk of malignancies in patients with RA. Cancer surveillance is imperative in all patients with RA. PMID:27630714

  2. Risk of Malignant Neoplasm in Patients with Incident Rheumatoid Arthritis 1980–2007 in relation to a Comparator Cohort: A Population-Based Study

    Science.gov (United States)

    Wright, Kerry

    2016-01-01

    Objective. To determine whether the incidence of malignancy is increased in patients with rheumatoid arthritis (RA) compared to a matched comparison cohort and to identify risk for any individual malignancy in RA. Methods. A cohort of 813 Olmsted County, Minnesota, residents who first fulfilled 1987 ACR criteria for RA in 1980–2007 was previously identified by medical record review. Medical records of 813 RA cases and a comparison cohort of age and sex matched Olmsted County residents without RA were evaluated retrospectively for cancer occurrence. Patients in both cohorts were followed until death, migration from Olmsted County, or 12/31/2014. Results. The RA and non-RA cohorts (mean age at incidence/index date: 55.9 [SD: 15.7] years; 68.4% females in both cohorts) were followed on average of 14.1 (SD: 7.7) and 14.9 (SD: 8.1) years, respectively. Prior to RA incidence/index date, 52 RA patients and 66 non-RA subjects had malignancies excluding NMSC (p = 0.21). During follow-up, significantly more malignancies occurred in patients with RA (n = 143) than in comparator subjects (n = 118; hazard ratio: 1.32; p = 0.027). Inclusion of NMSC obviated this difference. Conclusion. After excluding NMSC, there was a small to moderately increased risk of malignancies in patients with RA. Cancer surveillance is imperative in all patients with RA.

  3. 78 FR 38949 - Computer Security Incident Coordination (CSIC): Providing Timely Cyber Incident Response

    Science.gov (United States)

    2013-06-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE National Institute of Standards and Technology Computer Security Incident Coordination (CSIC): Providing... Technology (NIST) is seeking information relating to Computer Security Incident Coordination (CSIC). NIST...

  4. EarthSpace: The Higher Education Clearinghouse for Earth and Space Sciences

    Science.gov (United States)

    Dalton, H.; Cobabe-Ammann, E. A.; Shipp, S. S.

    2012-12-01

    EarthSpace is a searchable database of undergraduate classroom materials designed specifically for faculty teaching planetary sciences, Earth sciences, astrophysics, and solar and space physics at the introductory and upper division levels. Modeled after the highly successful SERC clearinghouse for geosciences assets, EarthSpace was designed for easy submission of classroom assets, from homework and computer interactives to laboratory exercises, lectures, and demonstrations. The site capabilities are being expanded to allow assignment of a unique Digital Object Identifier (DOI) to submitted materials, which will provide material developers a way to identify their submitted materials as publications on their CVs. EarthSpace materials are automatically cross-posted to other digital libraries (e.g., ComPADRE) and virtual higher education communities (e.g., Connexions), providing a wider distribution of the resources. In addition to classroom materials, EarthSpace provides the latest news and information about educational research and best practices, funding opportunities, and ongoing efforts and collaborations for undergraduate education. This information is emailed monthly in a newsletter to faculty members via the community mailing list, HENews. HENews is a place for the higher education community to share and receive news and information about higher education, teaching, and Earth and space science. EarthSpace also has an RSS feed to notify members when items are added. EarthSpace is a community-driven effort; higher education faculty members contribute and review materials and thus influence the content provided on the site. All materials are peer-reviewed before posting, and authors adhere to the Creative Commons Attribution (CC BY 3.0). You are invited to visit EarthSpace to search for teaching resources, submit your materials, or volunteer to review submitted resources in your discipline with a frequency designed to fit your schedule.

  5. Different regression equations relate age to the incidence of Lauren types 1 and 2 stomach cancer in the SEER database: these equations are unaffected by sex or race

    Directory of Open Access Journals (Sweden)

    Chiriva-Internati Maurizio

    2006-03-01

    Full Text Available Abstract Background Although impacts upon gastric cancer incidence of race, age, sex, and Lauren type have been individually explored, neither their importance when evaluated together nor the presence or absence of interactions among them have not been fully described. Methods This study, derived from SEER (Surveillance, Epidemiology, and End Results (SEER Program of the National Cancer Institute data, analyzed the incidences of gastric cancer between the years 1992–2001. There were 7882 patients who had developed gastric cancer. The total denominator population was 145,155, 669 persons (68,395,787 for 1992–1996, 78,759,882 for 1997–2001. Patients with multiple tumors were evaluated as per the default of the SEER*Stat program. 160 age-, five year period (1992–1996 vs 1997–2001-, sex-, race (Asian vs non-Asian-, Lauren type- specific incidences were derived to form the stratified sample evaluated by linear regression. (160 groups = 2 five year periods × 2 race groups × 2 sexes × 2 Lauren types × 10 age groups. Linear regression was used to analyze the importance of each of these explanatory variables and to see if there were interactions among the explanatory variables. Results Race, sex, age group, and Lauren type were found to be important explanatory variables, as were interactions between Lauren type and each of the other important explanatory variables. In the final model, the contribution of each explanatory variable was highly statistically significant (t > 5, d.f. 151, P Conclusion The change of the incidence of stomach cancer with respect to age for Lauren type 1 stomach cancer differs from that for Lauren type 2 stomach cancers. The relationships between age and Lauren type do not differ across gender or race. The results support the notion that Lauren type 1 and Lauren type 2 gastric cancers have different etiologies and different patterns of progression from pre-cancer to cancer. The results should be validated by

  6. HIV-1-related Hodgkin lymphoma in the era of combination antiretroviral therapy: incidence and evolution of CD4⁺ T-cell lymphocytes

    DEFF Research Database (Denmark)

    Bohlius, Julia; Schmidlin, Kurt; Boué, François;

    2011-01-01

    The risk of Hodgkin lymphoma (HL) is increased in patients infected with HIV-1. We studied the incidence and outcomes of HL, and compared CD4¿ T-cell trajectories in HL patients and controls matched for duration of combination antiretroviral therapy (cART). A total of 40 168 adult HIV-1-infected...... lost 98 CD4 cells (95% CI, -159 to -36 cells), whereas controls gained 35 cells (95% CI, 24-46 cells; P HIV-1 replication on cART may harbor HL....

  7. HIV-1-related Hodgkin lymphoma in the era of combination antiretroviral therapy: incidence and evolution of CD4⁺ T-cell lymphocytes

    DEFF Research Database (Denmark)

    Bohlius, Julia; Schmidlin, Kurt; Boué, François;

    2011-01-01

    The risk of Hodgkin lymphoma (HL) is increased in patients infected with HIV-1. We studied the incidence and outcomes of HL, and compared CD4⁺ T-cell trajectories in HL patients and controls matched for duration of combination antiretroviral therapy (cART). A total of 40 168 adult HIV-1-infected...... lost 98 CD4 cells (95% CI, -159 to -36 cells), whereas controls gained 35 cells (95% CI, 24-46 cells; P HIV-1 replication on cART may harbor HL....

  8. Relations of the Mediterranean dietary pattern with insulin resistance and diabetes incidence in the Multi-Ethnic Study of Atherosclerosis (MESA)

    OpenAIRE

    Abiemo, Eunice E.; Alonso, Alvaro; Jennifer A Nettleton; Steffen, Lyn M.; Bertoni, Alain G.; Jain, Aditya; Lutsey, Pamela L.

    2012-01-01

    Type 2 diabetes is a highly prevalent but preventable disorder. We assessed the association between an a priori Mediterranean diet score (MeDiet) and fasting glucose and insulin at baseline and incident type 2 diabetes after 6-year follow-up in MESA. Dietary intake was measured at baseline by a 127-item food frequency questionnaire in 5,390 men and women aged 45-84 years free of prevalent diabetes and clinical CVD. A MeDiet score was created based on intake of 10 food components: vegetables, ...

  9. Incidência e severidade do "furo de bala" em folhas da ameixeira sob doses de nitrogênio e potássio Incidence and severity of 'shot hole' in plum´s leaves related into nitrogen and potassium doses

    Directory of Open Access Journals (Sweden)

    Inês Tutida

    2007-10-01

    Full Text Available A produção integrada (PI vem suprir uma demanda crescente de frutos de qualidade, garantir segurança alimentar, produção com qualidade ambiental e rastreabilidade. Na visão da PI, as práticas da adubação e do controle de doenças estão intimamente relacionadas; no entanto, tem sido negligenciadas e pouco estudadas, principalmente para a doença "furo de bala" (Wilsonomyces carpophilus em folhas de ameixeira (Prunus salicina. O objetivo deste trabalho foi avaliar a incidência e severidade dessa doença em doses combinadas de adubação com N e K em dois ciclos de cultivo comercial de ameixeira cv "Reubennel", no município de Araucária (PR. Foram utilizadas cinco doses de N (40, 80, 120, 160 e 200kg ha-1ano-1 e duas de K (55 e 110kg ha-1ano-1. Realizaram-se sete avaliações para incidência e severidade a cada 20 dias, no período de novembro/2004 a março/2005 e em data única em outubro/2005. Os dados da primeira safra foram integralizados no tempo, constituindo a área abaixo da curva de progresso da doença (AACPD da incidência e severidade, e os dados foram analisados estatisticamente pela teoria dos modelos lineares generalizados para dados longitudinais. A doença foi mais severa no segundo ano de avaliação, sendo observado o máximo de 0,70 e 2,25 para o primeiro e o segundo ano, respectivamente. A incidência e a severidade de "furo de bala" em folhas de ameixeira são superiores nas doses de 160 e 200kg ha-1ano-1 de nitrogênio. O potássio não interfere na incidência e severidade da doença devido ao seu elevado teor encontrado no solo e na planta.Integrated Production (IP can provide the growing demand for quality fruit, food safety, environmental protection, and product traceability. In IP, fertilization practices and disease control are viewed as being closely related. However, this linkage has been mostly ignored and few studies are available concerning the 'shot hole' phytopathogen (Wilsonomyces carpophilus in

  10. Science Information Requirements of Scientists: The Need for a Scientific Request Receiver and Processor in an Information Clearinghouse, Technical Report 2.

    Science.gov (United States)

    Kinkade, Robert G.; And Others

    Determined were the functional design requirements of two components of an information system, the request-receiver and request-processor. The participants were 46 university biological scientists in the Washington, D.C. area who agreed to place requests by telephone with a specially established clearinghouse. A trained, experienced biological…

  11. Amelia : A Multi-Center Descriptive Epidemiologic Study in a Large Dataset from the International Clearinghouse for Birth Defects Surveillance and Research, and Overview of the Literature

    NARCIS (Netherlands)

    Bermejo-Sanchez, Eva; Cuevas, Lourdes; Amar, Emmanuelle; Bakker, Marian K.; Bianca, Sebastiano; Bianchi, Fabrizio; Canfield, Mark A.; Castilla, Eduardo E.; Clementi, Maurizio; Cocchi, Guido; Feldkamp, Marcia L.; Landau, Danielle; Leoncini, Emanuele; Li, Zhu; Lowry, R. Brian; Mastroiacovo, Pierpaolo; Mutchinick, Osvaldo M.; Rissmann, Anke; Ritvanen, Annukka; Scarano, Gioacchino; Siffel, Csaba; Szabova, Elena; Martinez-Frias, Maria-Luisa

    2011-01-01

    This study describes the epidemiology of congenital amelia (absence of limb/s), using the largest series of cases known to date. Data were gathered by 20 surveillance programs on congenital anomalies, all International Clearinghouse for Birth Defects Surveillance and Research members, from all conti

  12. Teaching Strategies for Improving Algebra Knowledge in Middle and High School Students. Educator's Practice Guide. What Works Clearinghouse.™ NCEE 2015-4010

    Science.gov (United States)

    Star, Jon R.; Foegen, Anne; Larson, Matthew R.; McCallum, William G.; Porath, Jane; Zbiek, Rose Mary; Caronongan, Pia; Furgeson, Joshua,; Keating, Betsy; Lyskawa, Julia

    2015-01-01

    Mastering algebra is important for future math and postsecondary success. Educators will find practical recommendations for how to improve algebra instruction in the What Works Clearinghouse (WWC) practice guide, "Teaching Strategies for Improving Algebra Knowledge in Middle and High School Students". The methods and examples included in…

  13. Incident Information Management Tool

    CERN Document Server

    Pejovic, Vladimir

    2015-01-01

    Flaws of\tcurrent incident information management at CMS and CERN\tare discussed. A new data\tmodel for future incident database is\tproposed and briefly described. Recently developed draft version of GIS-­‐based tool for incident tracking is presented.

  14. Analysis of the incidence of disease among the primary school pupils related to the organization of the physical education provided to the medically fragile children

    Directory of Open Access Journals (Sweden)

    Ganna Kazantseva

    2015-12-01

    Full Text Available Purpose: to research the breadth and type of the diseases among the primary school pupils aiming on the physical education optimization. Material and Methods: general data of the incidence of disease among the primary school pupils was revealed in the analysis of the medical documentation for 235 pupils of 1–4 grades at the general secondary school-lyceum in urban village Novofyodorovka. Results: it was revealed that the most wide spread health disorders at the primary school pupils are frequent respiratory diseases, functional disorders of locomotor apparatus and visual organs. Conclusions: the need of systematical application of the eyes exercises, breathing exercises as well as exercises for prophylaxis and correction of the skeleton deformations has been shown to increase the health-improving character of the physical education lessons at the primary school

  15. Ischemic Heart Disease Incidence in Relation to Fine versus Total Particulate Matter Exposure in a U.S. Aluminum Industry Cohort.

    Science.gov (United States)

    Neophytou, Andreas M; Noth, Elizabeth M; Liu, Sa; Costello, Sadie; Hammond, S Katharine; Cullen, Mark R; Eisen, Ellen A

    2016-01-01

    Ischemic heart disease (IHD) has been linked to exposures to airborne particles with an aerodynamic diameter TPM). To assess potential benefits of PM2.5 monitoring, we compared the exposure-response relationships between both PM2.5 and TPM and incidence of IHD in a cohort of active aluminum industry workers. To account for the presence of time varying confounding by health status we applied marginal structural Cox models in a cohort followed with medical claims data for IHD incidence from 1998 to 2012. Analyses were stratified by work process into smelters (n = 6,579) and fabrication (n = 7,432). Binary exposure was defined by the 10th-percentile cut-off from the respective TPM and PM2.5 exposure distributions for each work process. Hazard Ratios (HR) comparing always exposed above the exposure cut-off to always exposed below the cut-off were higher for PM2.5, with HRs of 1.70 (95% confidence interval (CI): 1.11-2.60) and 1.48 (95% CI: 1.02-2.13) in smelters and fabrication, respectively. For TPM, the HRs were 1.25 (95% CI: 0.89-1.77) and 1.25 (95% CI: 0.88-1.77) for smelters and fabrication respectively. Although TPM and PM2.5 were highly correlated in this work environment, results indicate that, consistent with biologic plausibility, PM2.5 is a stronger predictor of IHD risk than TPM. Cardiovascular risk management in the aluminum industry, and other similar work environments, could be better guided by exposure surveillance programs monitoring PM2.5. PMID:27249060

  16. Centenarian Rates and Life Expectancy Related to the Death Rates of Multiple Sclerosis, Asthma, and Rheumatoid Arthritis and the Incidence of Type 1 Diabetes in Children.

    Science.gov (United States)

    Lens-Pechakova, Lilia S

    2016-02-01

    The autoimmune diseases are among the 10 leading causes of death for women and the number two cause of chronic illness in America as well as a predisposing factor for cardiovascular diseases and cancer. Patients of some autoimmune diseases have shown a shorter life span and are a model of accelerated immunosenescence. Conversely, centenarians are used as a model of successful aging and have shown several immune parameters that are better preserved and lower levels of autoantibodies. The study reported here focused on clarifying the connection between longevity and some autoimmune and allergic diseases in 29 developed Organisation for Economic Co-operation and Development (OECD) countries, because multidisciplinary analyses of the accelerated or delayed aging data could show a distinct relationship pattern, help to identify common factors, and determine new important factors that contribute to longevity and healthy aging. The relationships between the mortality rates data of multiple sclerosis (MS), rheumatoid arthritis (RA), asthma, the incidence of type 1 diabetes (T1D) from one side and centenarian rates (two sets) as well as life expectancy data from the other side were assessed using regression models and Pearson correlation coefficients. The data obtained correspond to an inverse linear correlation with different degrees of linearity. This is the first observation of a clear tendency of diminishing centenarian rates or life expectancy in countries having higher death rates of asthma, MS, and RA and a higher incidence of T1D in children. The conclusion is that most probably there are common mechanistic pathways and factors affecting the above diseases and at the same time but in the opposite direction the processes of longevity. Further study, comparing genetic data, mechanistic pathways, and other factors connected to autoimmune diseases with those of longevity could clarify the processes involved, so as to promote longevity and limit the expansion of those

  17. Cumulative incidence for wait-list death in relation to length of queue for coronary-artery bypass grafting: a cohort study

    Directory of Open Access Journals (Sweden)

    Levy Adrian R

    2006-08-01

    Full Text Available Abstract Background In deciding where to undergo coronary-artery bypass grafting, the length of surgical wait lists is often the only information available to cardiologists and their patients. Our objective was to compare the cumulative incidence for death on the wait list according to the length of wait lists at the time of registration for the operation. Methods The study cohort included 8966 patients who registered to undergo isolated coronary-artery bypass grafting (82.4% men; 71.9% semi-urgent; 22.4% non-urgent. The patients were categorized according to wait-list clearance time at registration: either "1 month or less" or "more than 1 month". Cumulative incidence for wait-list death was compared between the groups, and the significance of difference was tested by means of regression models. Results Urgent patients never registered on a wait list with a clearance time of more than 1 month. Semi-urgent patients registered on shorter wait lists more often than non-urgent patients (79.1% vs. 44.7%. In semi-urgent and non-urgent patients, the observed proportion of wait-list deaths by 52 weeks was lower in category "1 month or less" than in category "more than 1 month" (0.8% [49 deaths] vs. 1.6% [39 deaths], P P Conclusion Long wait lists for coronary-artery bypass grafting are associated with increased probability that a patient dies before surgery. Physicians who advise patients where to undergo cardiac revascularization should consider the risk of pre-surgical death that is associated with the length of a surgical wait list.

  18. Centenarian Rates and Life Expectancy Related to the Death Rates of Multiple Sclerosis, Asthma, and Rheumatoid Arthritis and the Incidence of Type 1 Diabetes in Children.

    Science.gov (United States)

    Lens-Pechakova, Lilia S

    2016-02-01

    The autoimmune diseases are among the 10 leading causes of death for women and the number two cause of chronic illness in America as well as a predisposing factor for cardiovascular diseases and cancer. Patients of some autoimmune diseases have shown a shorter life span and are a model of accelerated immunosenescence. Conversely, centenarians are used as a model of successful aging and have shown several immune parameters that are better preserved and lower levels of autoantibodies. The study reported here focused on clarifying the connection between longevity and some autoimmune and allergic diseases in 29 developed Organisation for Economic Co-operation and Development (OECD) countries, because multidisciplinary analyses of the accelerated or delayed aging data could show a distinct relationship pattern, help to identify common factors, and determine new important factors that contribute to longevity and healthy aging. The relationships between the mortality rates data of multiple sclerosis (MS), rheumatoid arthritis (RA), asthma, the incidence of type 1 diabetes (T1D) from one side and centenarian rates (two sets) as well as life expectancy data from the other side were assessed using regression models and Pearson correlation coefficients. The data obtained correspond to an inverse linear correlation with different degrees of linearity. This is the first observation of a clear tendency of diminishing centenarian rates or life expectancy in countries having higher death rates of asthma, MS, and RA and a higher incidence of T1D in children. The conclusion is that most probably there are common mechanistic pathways and factors affecting the above diseases and at the same time but in the opposite direction the processes of longevity. Further study, comparing genetic data, mechanistic pathways, and other factors connected to autoimmune diseases with those of longevity could clarify the processes involved, so as to promote longevity and limit the expansion of those

  19. Grazing incidence beam expander

    Energy Technology Data Exchange (ETDEWEB)

    Akkapeddi, P.R.; Glenn, P.; Fuschetto, A.; Appert, Q.; Viswanathan, V.K.

    1985-01-01

    A Grazing Incidence Beam Expander (GIBE) telescope is being designed and fabricated to be used as an equivalent end mirror in a long laser resonator cavity. The design requirements for this GIBE flow down from a generic Free Electron Laser (FEL) resonator. The nature of the FEL gain volume (a thin, pencil-like, on-axis region) dictates that the output beam be very small. Such a thin beam with the high power levels characteristic of FELs would have to travel perhaps hundreds of meters or more before expanding enough to allow reflection from cooled mirrors. A GIBE, on the other hand, would allow placing these optics closer to the gain region and thus reduces the cavity lengths substantially. Results are presented relating to optical and mechanical design, alignment sensitivity analysis, radius of curvature analysis, laser cavity stability analysis of a linear stable concentric laser cavity with a GIBE. Fabrication details of the GIBE are also given.

  20. Cyber Incidents Involving Control Systems

    Energy Technology Data Exchange (ETDEWEB)

    Robert J. Turk

    2005-10-01

    The Analysis Function of the US-CERT Control Systems Security Center (CSSC) at the Idaho National Laboratory (INL) has prepared this report to document cyber security incidents for use by the CSSC. The description and analysis of incidents reported herein support three CSSC tasks: establishing a business case; increasing security awareness and private and corporate participation related to enhanced cyber security of control systems; and providing informational material to support model development and prioritize activities for CSSC. The stated mission of CSSC is to reduce vulnerability of critical infrastructure to cyber attack on control systems. As stated in the Incident Management Tool Requirements (August 2005) ''Vulnerability reduction is promoted by risk analysis that tracks actual risk, emphasizes high risk, determines risk reduction as a function of countermeasures, tracks increase of risk due to external influence, and measures success of the vulnerability reduction program''. Process control and Supervisory Control and Data Acquisition (SCADA) systems, with their reliance on proprietary networks and hardware, have long been considered immune to the network attacks that have wreaked so much havoc on corporate information systems. New research indicates this confidence is misplaced--the move to open standards such as Ethernet, Transmission Control Protocol/Internet Protocol, and Web technologies is allowing hackers to take advantage of the control industry's unawareness. Much of the available information about cyber incidents represents a characterization as opposed to an analysis of events. The lack of good analyses reflects an overall weakness in reporting requirements as well as the fact that to date there have been very few serious cyber attacks on control systems. Most companies prefer not to share cyber attack incident data because of potential financial repercussions. Uniform reporting requirements will do much to make this

  1. Interaction between obesity and the NFKB1 - 94ins/delATTG promoter polymorphism in relation to incident acute coronary syndrome: a follow up study in three independent cohorts.

    Directory of Open Access Journals (Sweden)

    Jakob Gerhard Stegger

    Full Text Available INTRODUCTION: The NF-κB transcription factor family regulates several genes encoding pro-inflammatory and anti-inflammatory proteins in adipose tissues and in atherosclerotic plaques. The deletion variant allele of the NFKB1 - 94ins/delATTG promoter polymorphism leads to lower transcript levels of the p50 subunit, and the variant allele has been associated with the risk of several inflammatory diseases as well as coronary heart disease where inflammation is important in the pathogenesis. The objective of this study was to explore the potential interaction between the NFKB1-94ins/delATTG promoter polymorphism and general, abdominal, and gluteofemoral obesity in relation to the risk of incident acute coronary syndrome (ACS in three large independent cohorts. METHODS AND RESULTS: The analyses were conducted in the Danish prospective study Diet, Cancer and Health and the two US based cohorts; Nurses' Health Study and Health Professionals Follow-up Study. We conducted sex stratified analyses that included 1202 male and 708 female cases of incident ACS. We observed a positive association for general and abdominal obesity with risk of incident ACS, independent of genotype in both genders. Gluteofemoral obesity was negatively associated with ACS risk in women independent of genotype, whereas there was no clear association for men. We calculated the relative excess risk due to interaction (RERI and observed a statistically significant excess risk among men jointly exposed to general or abdominal obesity and the variant allele of the NFKB1-94ATTG polymorphism, whereas there was a tendency towards sub-additivity for gluteofemoral obesity. The excess risks in all analyses were, however, small and could not clearly be demonstrated in women. CONCLUSION: The variant allele of the NFKB1-94ins/delATTG promoter polymorphism did not substantially modify the association between obesity and incident ACS.

  2. Study of the relation between Body Constitution and incidence tendency of depression or anxiety%体质与抑郁、焦虑发病倾向关系的调查研究

    Institute of Scientific and Technical Information of China (English)

    邓红月; 陈玉玲

    2011-01-01

    目的 探讨体质与抑郁、焦虑发病倾向的关系.方法 采用问卷方式对社区居民进行调查.结果 偏颇体质的抑郁、焦虑发病倾向高于平和体质的;气虚、湿热、气郁体质易有抑郁发病倾向,气虚、阳虚、湿热、气郁、特禀体质易有焦虑发病倾向.结论 不同体质的抑郁、焦虑发病倾向差异有统计学意义.在抑郁、焦虑的预防中可以针对体质因素进行干预.%Objective To discuss the relation between Body Constitution and incidence tendency of depres sion or anxiety. Methods The community residents were investigated with questionnaire. Results The incidence tendency of depression and anxiety with Biased Constitution was larger than with Peace. The Qi-asthenia, Damp-heat, Qi-stagnation constitutions had high tendency of depression. The Qi-asthenia, Yang-asthenia, Damp-heat, Qi-stagna tion and allergic constitutions had high tendency of anxiety. Conclusion Different constitution has distinct difference of incidence tendency, which can be used in preventing depression and anxiety.

  3. Incidencia de caídas en un hospital de nivel 1: factores relacionados Incidence of falls in a University Hospital: factors related

    Directory of Open Access Journals (Sweden)

    Juan Manuel Laguna-Parras

    2011-12-01

    the term falls as the result of any event which precipitate someone to the ground against their will. Aims: to analyze the incidence of falls, the profile of patients who fall in the hospital and to identify causes and effects. Methodology: design: Descriptive study on falls reported in Jaen's Hospital, which includes any fall (36 that has taken place at some time of hospital stay. Data collection was performed by each unit supervisors developed a data collection sheet. Data were transcribed to a database. Variables collected were: demographic data, date and time of the fall event, unit which produces the fall, Morse scale score, previous falls, fall circumstances, factors such as medication, cognitive, functional factors environment, care after the fall and need for assistive devices. Results: during the period under review there were a total of 36 falls, representing an incidence of 0.18%. Higher frequency of falls occurred in mental health units and palliative care. Conclusions: after analyzing the result we state that patients who fall in our hospital have an average age of 63 years, there are no differences regarding sex of patients, according to the morse score scale most patiens had low risk of falling, most have no history of previous falls and the mayority of falls ocurred in patient's room.

  4. Incidence Handling and Response System

    CERN Document Server

    Kalbande, Prof Dhananjay R; Singh, Mr Manish

    2009-01-01

    A computer network can be attacked in a number of ways. The security-related threats have become not only numerous but also diverse and they may also come in the form of blended attacks. It becomes difficult for any security system to block all types of attacks. This gives rise to the need of an incidence handling capability which is necessary for rapidly detecting incidents, minimizing loss and destruction, mitigating the weaknesses that were exploited and restoring the computing services. Incidence response has always been an important aspect of information security but it is often overlooked by security administrators. in this paper, we propose an automated system which will handle the security threats and make the computer network capable enough to withstand any kind of attack. we also present the state-of-the-art technology in computer, network and software which is required to build such a system.

  5. Conjoined Twins: A Worldwide Collaborative Epidemiological Study of the International Clearinghouse for Birth Defects Surveillance and Research

    Science.gov (United States)

    MUTCHINICK, OSVALDO M.; LUNA-MUÑOZ, LEONORA; AMAR, EMMANUELLE; BAKKER, MARIAN K.; CLEMENTI, MAURIZIO; COCCHI, GUIDO; DUTRA, MARIA DA GRAÇA; FELDKAMP, MARCIA L.; LANDAU, DANIELLE; LEONCINI, EMANUELE; LI, ZHU; LOWRY, BRIAN; MARENGO, LISA K.; MARTÍNEZ-FRÍAS, MARÍA-LUISA; MASTROIACOVO, PIERPAOLO; MÉTNEKI, JULIA; MORGAN, MARGERY; PIERINI, ANNA; RISSMAN, ANKE; RITVANEN, ANNUKKA; SCARANO, GIOACCHINO; SIFFEL, CSABA; SZABOVA, ELENA; ARTEAGA-VÁZQUEZ, JAZMÍN

    2015-01-01

    Conjoined twins (CT) are a very rare developmental accident of uncertain etiology. Prevalence has been previously estimated to be 1 in 50,000 to 1 in 100,000 births. The process by which monozygotic twins do not fully separate but form CT is not well understood. The purpose of the present study was to analyze diverse epidemiological aspects of CT, including the different variables listed in the Introduction Section of this issue of the Journal. The study was made possible using the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR) structure. This multicenter worldwide research includes the largest sample of CT ever studied. A total of 383 carefully reviewed sets of CT obtained from 26,138,837 births reported by 21 Clearinghouse Surveillance Programs (SP) were included in the analysis. Total prevalence was 1.47 per 100,000 births (95% CI: 1.32–1.62). Salient findings including an evident variation in prevalence among SPs: a marked variation in the type of pregnancy outcome, a similarity in the proportion of CT types among programs: a significant female predominance in CT: particularly of the thoracopagus type and a significant male predominance in parapagus and parasitic types: significant differences in prevalence by ethnicity and an apparent increasing prevalence trend in South American countries. No genetic, environmental or demographic significant associated factors were identified. Further work in epidemiology and molecular research is necessary to understand the etiology and pathogenesis involved in the development of this fascinating phenomenon of nature. PMID:22002822

  6. Semantic Theme Analysis of Pilot Incident Reports

    Science.gov (United States)

    Thirumalainambi, Rajkumar

    2009-01-01

    Pilots report accidents or incidents during take-off, on flight and landing to airline authorities and Federal aviation authority as well. The description of pilot reports for an incident contains technical terms related to Flight instruments and operations. Normal text mining approaches collect keywords from text documents and relate them among documents that are stored in database. Present approach will extract specific theme analysis of incident reports and semantically relate hierarchy of terms assigning weights of themes. Once the theme extraction has been performed for a given document, a unique key can be assigned to that document to cross linking the documents. Semantic linking will be used to categorize the documents based on specific rules that can help an end-user to analyze certain types of accidents. This presentation outlines the architecture of text mining for pilot incident reports for autonomous categorization of pilot incident reports using semantic theme analysis.

  7. Spatiotemporal patterns, annual baseline and movement-related incidence of Streptococcus agalactiae infection in Danish dairy herds: 2000–2009

    DEFF Research Database (Denmark)

    Mweu, Marshal M.; Nielsen, Søren S.; Hisham Beshara Halasa, Tariq;

    2014-01-01

    Several decades after the inception of the five-point plan for the control of contagious mastitis pathogens, Streptococcus agalactiae (S. agalactiae) persists as a fundamental threat to the dairy industry in many countries. A better understanding of the relative importance of within- and between...... surveillance scheme as well as live cattle movements into dairy herds during the specified 10-year period. The results indicated that the predicted risk of a herd becoming infected with S. agalactiae varied spatiotemporally; the risk being more homogeneous and higher in the period after 2005. Additionally...

  8. Increased Incidence Rate of Trauma- and Stressor-Related Disorders in Denmark After the September 11, 2001, Terrorist Attacks in the United States

    DEFF Research Database (Denmark)

    Hansen, Bertel T; Østergaard, Søren D; Sønderskov, Kim M;

    2016-01-01

    The terrorist attacks that occurred on September 11, 2001 (hereafter referred to as 9/11) in the United States had a profound impact on the physical and mental health of Americans, but the effects beyond the United States are largely unknown. To understand the wider aftermath, we examined...... for other disorders. This is consistent with the prominent role of external stressors in the etiology of trauma- and stressor-related disorders. The results indicate that the effects of 9/11 on mental disorders extended across the Atlantic Ocean to Denmark. Thus, the impact of terrorist attacks on mental...

  9. Stavudine- and nevirapine-related drug toxicity while on generic fixed-dose antiretroviral treatment: incidence, timing and risk factors in a three-year cohort in Kigali, Rwanda.

    Science.gov (United States)

    van Griensven, Johan; Zachariah, Rony; Rasschaert, Freya; Mugabo, Jules; Atté, Edi F; Reid, Tony

    2010-02-01

    This cohort study was conducted to report on the incidence, timing and risk factors for stavudine (d4T)- and nevirapine (NVP)-related severe drug toxicity (requiring substitution) with a generic fixed-dose combination under program conditions in Kigali, Rwanda. Probability of 'time to first toxicity-related drug substitution' was estimated using the Kaplan-Meier method and Cox-proportional hazards modeling was used to identify risk factors. Out of 2190 adults (median follow-up: 1.5 years), d4T was replaced in 175 patients (8.0%) for neuropathy, 69 (3.1%) for lactic acidosis and 157 (7.2%) for lipoatrophy, which was the most frequent toxicity by 3 years of antiretroviral treatment (ART). NVP was substituted in 4.9 and 1.3% of patients for skin rash and hepatotoxicity, respectively. Use of d4T 40 mg was associated with increased risk of lipoatrophy and early (strategies.

  10. Large whale incident database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Large whale stranding, death, ship strike and entanglement incidents are all recorded to monitor the health of each population and track anthropogenic factors that...

  11. Police Incident Blotter (Archive)

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The Police Blotter Archive contains crime incident data after it has been validated and processed to meet Uniform Crime Reporting (UCR) standards, published on a...

  12. NRC Incident Response Plan

    International Nuclear Information System (INIS)

    The Nuclear Regulatory Commission (NRC) regulates civilian nuclear activities to protect the public health and safety and to preserve environmental quality. An Incident Response Plan had been developed and has now been revised to reflect current Commission policy. NUREG-0728, Rev. 2 assigns responsibilities for responding to any potentially threatening incident involving NRC licensed activities and for assuring that the NRC will fulfill it statutory mission. This report has also been reproduced for staff use as NRC Manual Chapter 0502

  13. National Network of Eisenhower Regional Consortia and Clearinghouse: Supporting the Improvement of Mathematics and Science in America's Schools. Evaluation Summary Report for 1995-2000 with In-Depth Evaluation of Training and Technical Assistance, Dissemination, and Collaboration and Networking Services.

    Science.gov (United States)

    National Network of Eisenhower Regional Consortia and National Clearinghouse.

    This report, addressed to sponsors and partners of the Eisenhower consortia and clearinghouse network as well as the staff of those organizations, contains the evaluation summary report of the National Network of Eisenhower Regional Consortia and Clearinghouse. It summarizes network outcomes over the 5-year period between 1995-2000. The report…

  14. 中国2008年肿瘤发病和死亡情况估计及预测%Estimation and prediction on cancer related incidence and mortality in China, 2008

    Institute of Scientific and Technical Information of China (English)

    代敏; 任建松; 李霓; 李倩; 杨琳; 陈玉恒

    2012-01-01

    Objective To estimate the incidence and mortality rates of cancers in China in 2008.Methods Data from 36 cancer registry sites in China and from the Third National Death Survey in China (2004-2005) were used to estimate the incidence and mortality of cancer in China in 2008 by using mathematical models.Prediction on cancer incidence and mortality in the next 20 years was carried out.Results According to the age-standardized incidence rates,the top cancer sites were lung,stomach,liver,breast,oesophageal,colorectal,corpus uterine,cervical,leukemia and brain tumor.According to the age-standardized mortality rates,the top cancers in China were lung cancer,liver cancer,stomach cancer,oesophageal cancer,colorectal cancer,breast cancer,cervical cancer,leukemia,brain tumor and corpus uterine cancer.Cancer happened more frequently among people older than 40 years,particularly among males.Data related to prediction showed that the incidence and mortality of cancer in China would gradually increase in the next 20 years.Conclusion Both incidence and mortality of cancers in China had been increasing,with the most common cancers appeared to be lung,breast and digestive tract cancers,in China.People older than 40 years should be under specific care to receive prevention and care on cancer,with males in particular.%目的 估计2008年中国肿瘤发病和死亡的情况,并预测今后20年发病数和死亡数.方法 根据中国36个肿瘤登记点的数据以及全国第三次死因调查(2004-2005年)的结果,估计2008年恶性肿瘤的发病和死亡情况,预测2010、2015、2020、2025和2030年的发病数和死亡数.结果 中国按世界人口标化发病率排前10位的癌症是肺癌(33.5/10万)、胃癌、肝癌、乳腺癌、食管癌、结直肠癌、子宫体癌、子宫颈癌、白血病和脑瘤/神经肿瘤(4.4/10万);按世界人口标化死亡率排前10位的癌症依次为肺癌(28.7/10万)、肝癌、胃癌、食管癌、结直肠癌、乳腺癌、子

  15. Incidence of Federal and State Gasoline Taxes

    OpenAIRE

    Chouinard, Hayley; Perloff, Jeffrey M.

    2003-01-01

    The federal specific gasoline tax falls equally on consumers and wholesalers; whereas state specific taxes fall almost entirely on consumers. The consumer incidence of state taxes is greater in states that use relatively little gasoline.

  16. A relação entre o acompanhamento médico e a incidência de lesões esportivas em atletas jovens de São Paulo Relation between medical clinical monitoring and the incidence of sports injuries in young athletes of São Paulo

    Directory of Open Access Journals (Sweden)

    Simone Sagres Arena

    2007-08-01

    Full Text Available O objetivo deste estudo foi relacionar a estrutura médica de atendimento de 20 clubes de São Paulo com a incidência de lesões esportivas de atletas jovens praticantes do basquetebol, futsal e voleibol. Para isso, foi utilizado um questionário de lesão com 323 atletas e uma entrevista estruturada com os médicos responsáveis. Foram identificadas 343 lesões esportivas ou 1,7 lesão/atleta/ano. Dos 20 clubes avaliados, apenas oito possuem atendimento médico especializado dentro da instituição. No basquetebol, não houve relação estatística entre a presença ou não do médico dentro do clube com as ocorrências de lesão. No futsal e no voleibol, o número de lesões foi maior com a presença do médico dentro do clube; isso porque nos clubes que não possuem médico, as lesões de menor gravidade não são detectadas. O estudo sugeriu reestruturação no atendimento médico oferecido aos atletas jovens.The objective of this study was to evaluate the relation between medical clinical monitoring and the incidence of the main sports injuries found in young athletes in sports modalities such basketball, indoor soccer and volleyball from 20 clubs located in São Paulo (Brazil. To obtain those data, a questionnaire was applied to 323 athletes and surveys were performed among eight physicians. The results of the study showed a total of 343 injuries or 1,7 injury/athlete/year. In basketball, there was not statistic relation between rates of injury and clinical monitoring in the club. In indoor soccer and volleyball, the rate of injury was bigger with clinical monitoring, because the injuries of less gravity do not are detected in clubs without physician. This study suggest specialized clinical care for young in sports clubs.

  17. Incidence of bacterial colpitis in gynecology outpatient department and analysis of related risk factors%妇科门诊细菌性阴道病发病率及相关危险因素分析

    Institute of Scientific and Technical Information of China (English)

    周亚芬; 张静

    2013-01-01

    目的 探讨妇科门诊细菌性阴道病发病情况及导致细菌性阴道炎发生的危险因素,降低其发病率.方法 对2012年6月在医院妇科门诊就诊诊断为阴道炎的150例患者进行病原菌检测及问卷调查,分析细菌性阴道病发病率及相关危险因素.结果 调查问卷回收率100.00%,合格率95.33%%%;诊断为细菌性阴道病者76例,发病率50.67%,外阴阴道假丝酵母菌病51例,发病率34.00%,滴虫性阴道炎23例,发病率15.33%;患者年龄、文化程度、月收入、流产次数、自行阴道冲洗、月经期用消毒卫生巾、非经期使用护垫、每周性生活次数、避孕方式、阴道炎史均是引起细菌性阴道病的单危险因素,差异有统计学意义(P<0.05);非条件logistic回归分析结果显示,自行阴道冲洗、非月经期使用护垫、阴道炎史是导致细菌性阴道病发生的独立危险因素,月经期使用消毒卫生巾、避孕套避孕是降低细菌性阴道病发生的保护因素.结论 妇科门诊细菌性阴道病发病率占阴道炎约50.00%,自行阴道冲洗、非月经期使用护垫及阴道炎史均能增加患有细菌性阴道病的危险性,月经期使用消毒卫生巾及避孕套避孕能减少细菌性阴道病患病概率.%OBJECTIVE To explore the incidence of bacterial colpitis in the gynecology clinic and analyze the related risk factors of the bacterial colpitis so as to reduce the incidence of this disease. METHODS A total of 150 patients who were diagnosed as the vaginitis and were treated in the gynecology outpatient department from Jan 2012 to Jun 2012 were enrolled in the study, the patients were tested for pathogens and were investigated with questionnaires, and the incidence of bacterial colpitis and the related risk factors were analyzed. RESULTS The recovery rate of the questionnaires was 100. 00% , and the qualified rate was 95. 33%. Totally 76 cases were diagnosed as the bacterial colpitis with

  18. X-ray relative intensities at incident photon energies across the L{sub i} (i=1–3) absorption edges of elements with 35≤Z≤92

    Energy Technology Data Exchange (ETDEWEB)

    Puri, Sanjiv, E-mail: sanjivpurichd@yahoo.com

    2014-07-15

    The intensity ratios, I{sub Lk}/I{sub Lα1} (k=l,η,α{sub 2},β{sub 1},β{sub 2,15},β{sub 3},β{sub 4},β{sub 5,7},β{sub 6},β{sub 9,10},γ{sub 1,5},γ{sub 6,8},γ{sub 2,3},γ{sub 4}) and I{sub Lj}/I{sub Lα} (j=β,γ), have been evaluated at incident photon energies across the L{sub i} (i=1–3) absorption edge energies of all the elements with 35≤Z≤92. Use is made of what are currently considered to be more reliable theoretical data sets of different physical parameters, namely, the L{sub i} (i=1–3) sub-shell photoionization cross sections based on the relativistic Hartree–Fock–Slater (RHFS) model, the X-ray emission rates based on the Dirac–Fock model, and the fluorescence and Coster–Kronig yields based on the Dirac–Hartree–Slater model. In addition, the Lα{sub 1} X-ray production cross sections for different elements at various incident photon energies have been tabulated so as to facilitate the evaluation of production cross sections for different resolved L X-ray components from the tabulated intensity ratios. Further, to assist evaluation of the prominent (L{sub i}−S{sub j}) (S{sub j}=M{sub j}, N{sub j} and i=1–3, j=1–7) resonant Raman scattered (RRS) peak energies for an element at a given incident photon energy (below the L{sub i} sub-shell absorption edge), the neutral-atom electron binding energies based on the relaxed orbital RHFS calculations are also listed so as to enable identification of the RRS peaks, which can overlap with the fluorescent X-ray lines. -- Highlights: •The L X-ray relative intensities and Lα{sub 1} XRP cross sections are evaluated using physical parameters based on the IPA models. •Comparison of the intensity ratios evaluated using the DHS and DF models based photoionization cross sections is presented. •Importance of many body effects including electron exchange effects is highlighted.

  19. 证据转化中心简介及应用%Brief Introduction and Application of Clearinghouse

    Institute of Scientific and Technical Information of China (English)

    关朕; 常健博; 范源; Iris Chi; Haluk Soydan; 拜争刚

    2015-01-01

    证据转化中心(Clearinghouse)在西方发达国家的知识转化中发挥着重要作用.其运用特定主题,针对特定的目标人群,以其严格的评价标准持续不断地向用户提供最新证据.证据转化中心要求客观透明地评价研究证据的科学性及实用性,为不同服务实践者提供当前最佳证据.其注重从“知识生产”到“知识转化”过程的这一特点,有效填充了研究与实践之间的鸿沟,未来必将在知识转化方面发挥重要作用.本文详细介绍了证据转化中心的历史、特征及其应用,举例说明中国儿童与老年健康证据转化数据库的建立,更加充分地体现其应用现状,为我国的知证决策提供参考.

  20. Incidência cumulativa anual de doenças musculoesqueléticas incapacitantes relacionadas ao trabalho em uma área urbana do Brasil Cumulative annual incidence of disabling work-related musculoskeletal disorders in an urban area of Brazil

    Directory of Open Access Journals (Sweden)

    Norma Suely Souto Souza

    2011-11-01

    Full Text Available Estimou-se a incidência cumulativa anual (ICA das doenças musculoesqueléticas incapacitantes que acometem a região cervical e/ou membros superiores (DMEMS relacionadas ao trabalho, entre trabalhadores do Regime Geral da Previdência Social (RGPS de Salvador, Bahia, Brasil. Trabalhadores que receberam benefícios por incapacidade temporária por DMEMS relacionadas ao trabalho foram considerados casos, em 2008. Os dados provêm dos sistemas administrativos do Instituto Nacional do Seguro Social (INSS e do Ministério do Trabalho e Emprego (MTE. A ICA foi de 15 por dez mil trabalhadores. Mulheres, os de menor renda e aqueles que trabalhavam no ramo de atividades financeiras e indústria de transformação tinham maior ICA-DMEMS do que os seus referentes. Mulheres com o menor rendimento (um salário mínimo: R$ 415,00 tiveram a maior ICA-DMEMS, de 123 casos por dez mil. Isso sugere desigualdade na ocorrência dessas enfermidades, indicando a necessidade de priorizar não só ações de prevenção, com foco na ergonomia e organização do trabalho, como também o diagnóstico precoce, tratamento e reabilitação profissional.This study focused on the annual cumulative incidence (ACI of disabling work-related musculoskeletal disorders affecting the neck and/or upper limbs (ULMSD among workers covered by the National Social Insurance System in the city of Salvador, Bahia State, Brazil. Cases were workers who received disability compensation benefits when unable to work due to ULMSD, during the year 2008. The data were obtained from the administrative systems of the National Social Insurance Institute and Ministry of Labor and Employment. ACI was 15 per 10,000 workers. Increased ACI of ULMSD was associated with female gender, lower income, and work in financial activities or manufacturing. Women earning the minimum wage (US$ 64.00 per month or less had the highest ACI of ULMSD (123 per 10,000, suggesting inequalities in the occurrence of these

  1. The incidence of cardiovascular events and its related risk factors in prehypertensive population%高血压前期人群中心脑血管事件发生情况及影响因素

    Institute of Scientific and Technical Information of China (English)

    吴寿岭; 钟吉文; 王丽晔; 高竞生; 郑晓明; 金成; 李金峰; 刘秀荣; 黄卫

    2012-01-01

    目的 观察高血压前期人群中心脑血管事件发生情况及影响因素.方法 采用前瞻性队列研究方法,以参加2006-07-2007-10健康查体的30~70岁开滦集团在职及离退休职工101 510人中,符合美国预防、检测、评估与 ‘治疗高血压全国联合委员会第7次报告(JNC 7)高血压前期诊断标准(30027人)和理想血压诊断标准(15614人)的人群作为观察队列.随访38.0~53.0(47.6±3.2)月,随访期间每半年收集1次新发心脑血管事件情况.观察高血压前期人群中心脑血管事件发生率并用多变量Cox比例风险回归模型分析影响心脑血管事件的因素.结果 与理想血压人群相比高血压前期人群的平均年龄较大;男性比例较高;三酰甘油、总胆固醇、低密度脂蛋白胆固醇和体质量指数水平高(均P<0.05).随访期间共发生461例心脑血管事件.高血压前期人群中总心脑血管事件、脑梗死、脑出血、心肌梗死和心脑血管病致死事件的累积发生率分别为1.19%、0.57%、0.20%、0.23%和0.23%,高于理想血压人群的0.67%、0.27%、0.12%、0.17%和0.15%,其中总心脑血管事件、脑梗死和脑出血累积发生率两组人群差异有统计学意义(均P<0.05).校正其他传统心血管危险因素后,高血压前期人群发生总心脑血管事件和脑梗死的RR分别较理想血压人群增加37%(95% CI 1.10~1.70)和56%(95% CI 1.10~2.20).结论 高血压前期人群的总心脑血管事件、脑梗死和脑出血累积发生率高于理想血压人群;高血压前期是总心脑血管事件和脑梗死的独立危险因素.%Objective To observe the incidence of cardiovascular events and its related risk factors in prehypertens-ives. Methods In this prospective cohort study, the data was derived from the KaiLuan study cohort (101 510 cases). A total of 30 027 prehypertensives and 15 614 normotensives (defined by the JNC 7) were enrolled (aged 30

  2. Analysis of incidence of postpartum depression and its related factors%产妇产后抑郁的发生率及相关性因素分析

    Institute of Scientific and Technical Information of China (English)

    王静

    2015-01-01

    Objective:To investigate incidence and related factors of postpartum depression. Methods:186 cases of pregnant women were randomly selected. Hospital anxiety and depression scale( HADS) and Edinburgh postnatal depression scale( EPDS) were used to investigatepostpartum depression, and self-designed postpartum depressionquestionnaire was applied to study the related influ-encing factors. The investigation was in the form ofquestionnaire survey. These patients were divided into normal group and depression group according to the findings. Results:The incidence of postpartum depression was 9. 14%. There were statistical differences in cul-turallevel, personality,living conditions,relationship between mother-in-law and daughter-in-law,relationship between husband and wife,mode of delivery,abnormal birthhistory,neonatal malformations, and neonatal birthweight between normal group and depression group. Moreover, postpartum depression's riskfactors were low education level, poor relationship between mother-in-law anddaughter-in-law,introvert personality,poorrelationship between husband and wife,cesarean section,a bad history of production,low birth weight, and neonatal malformations. Conclusions:Postpartum depression occurs at a high incidence rate and is multifactorially related;there-fore, a goodand psychological support should be given to the parturient women.%目的::探讨产妇产后抑郁的发生率及相关因素。方法:随机抽取分娩产妇186例,采用综合医院焦虑抑郁量表( HADS)和爱丁堡产后抑郁量表( EPDS)调查产妇产后抑郁情况,采用自编产后抑郁症的相关因素调查表调查影响产妇产后抑郁因素,调查方式为问卷调查。按调查结果分为正常组169例和抑郁组17例。结果:产妇产后抑郁症的发生率为9.14%,两组产妇在文化程度、性格、居住条件、婆媳关系、夫妻关系、分娩方式、不良产史、新生儿畸形、新生儿出生时体重上差异有统

  3. Incident users of antipsychotics

    DEFF Research Database (Denmark)

    Baandrup, Lone; Kruse, Marie

    2016-01-01

    PURPOSE: In Denmark, as well as in many other countries, consumption of antipsychotics is on the rise, partly due to increasing off-label use. The aim of this study was to analyze and quantify the extent of off-label use and polypharmacy in incident users of antipsychotic medication, and to exami....... As a consequence of the range of adverse effects associated with antipsychotic drug use, the documented widespread off-label prescribing practices warrant careful monitoring for adverse effects and prompt discontinuation in case of an unfavorable risk-benefit ratio.......PURPOSE: In Denmark, as well as in many other countries, consumption of antipsychotics is on the rise, partly due to increasing off-label use. The aim of this study was to analyze and quantify the extent of off-label use and polypharmacy in incident users of antipsychotic medication, and to examine...

  4. Incidence of dilated cardiomyopathy

    OpenAIRE

    Abelmann, Walter H.

    1985-01-01

    Full reliable data on the incidence and prevalence of dilated cardiomyopathy are not available. In the United States, at least 0.7% of cardiac deaths are attributable to cardiomyopathy. Dilated cardiomyopathy probably contributes the great majority of these cases. The mortality rate for cardiomyopathy in males is twice that of females, and for blacks it is 2.4 times that of whites. Cardiomyopathy was diagnosed in 0.67% of patients discharged from hospitals in 1979 with diagnoses of disease of...

  5. Contaminated Mexican steel incident

    International Nuclear Information System (INIS)

    This report documents the circumstances contributing to the inadvertent melting of cobalt 60 (Co-60) contaminated scrap metal in two Mexican steel foundries and the subsequent distribution of contaminated steel products into the United States. The report addresses mainly those actions taken by US Federal and state agencies to protect the US population from radiation risks associated with the incident. Mexico had much more serious radiation exposure and contamination problems to manage. The United States Government maintained a standing offer to provide technical and medical assistance to the Mexican Government. The report covers the tracing of the source to its origin, response actions to recover radioactive steel in the United States, and return of the contaminated materials to Mexico. The incident resulted in significant radiation exposures within Mexico, but no known significant exposure within the United States. Response to the incident required the combined efforts of the Nuclear Regulatory Commission (NRC), Department of Energy, Department of Transportation, Department of State, and US Customs Service (Department of Treasury) personnel at the Federal level and representatives of all 50 State Radiation Control Programs and, in some instances, local and county government personnel. The response also required a diplomatic interface with the Mexican Government and cooperation of numerous commercial establishments and members of the general public. The report describes the factual information associated with the event and may serve as information for subsequent recommendations and actions by the NRC. 8 figures

  6. Cancer incidence among waiters

    DEFF Research Database (Denmark)

    Reijula, Jere; Kjaerheim, Kristina; Lynge, Elsebeth;

    2015-01-01

    AIMS: To study cancer risk patterns among waiters in the Nordic countries. METHODS: We identified a cohort of 16,134 male and 81,838 female waiters from Denmark, Finland, Iceland, Norway and Sweden. During the follow-up period from 1961 to 2005, we found that 19,388 incident cancer cases were...... diagnosed. Standardised incidence ratio (SIR) was defined as the observed number of cancer cases divided by the expected number, based on national age, time period and gender-specific cancer incidence rates in the general population. RESULTS: The SIR of all cancers in waiters, in the five countries combined......, was 1.46 (95% CI 1.41-1.51) in men and 1.09 (1.07-1.11) in women. In male waiters, the SIR decreased from 1.79 (1.63-1.96) in 1961-1975, to 1.33 (1.26-1.40) in 1991-2005, but remained stable among women. The SIR among male waiters was highest for cancers in the pharynx (6.11; 95% CI 5.02-7.37), oral...

  7. 福利院老年人抑郁症状的发生及相关因素的分析%Analysis on incidence of elderly depressive disorder in Welfare Institution and its related factors

    Institute of Scientific and Technical Information of China (English)

    范红艳; 万巧琴

    2008-01-01

    目的 探讨福利院老人抑郁症状的发生情况和相关因素,从而为居住在福利院老人的抑郁症状的防治和护理提供参考依据.方法 对居住在某福利院的81位老人进行问卷调查,内容包括一般情况、精神状态简易速检表和老年抑郁量表.结果 8l位老人中抑郁症状发生率为29.6%,其中,抑郁症状得分与探视时间间隔长短、有无配偶、卧床与否、有无脑血管病、所患慢性病数量的多少有关.结论 福利院老人抑郁症状的发生率较高,提示我们要重视福利院老人抑郁症状的防治,加强对他们的心理护理和情感关怀,从而改善老人的心理健康状况,提高老人晚年的生活质量,更好的发挥社会养老的作用.%Objective To learn the incidence of elderly depressive disorder in Welfare Institution and its related factors so as to privide reference for cure and prevention and nursing of elderly depressive disorder in Welfare Institution. Methods 81 elderly patients in one Welfare Institution were investigated with questionaire, which includes general state of health, MMSE, GDS. Results 29.6% of 81 elderly patients showed depressive disorder, which was related to following factors, such interval of family visiting, spouse, lying in bed, cerebrovascular disease, the kinds of chronic disease. Conclusions The incidence of elderly depressive disorder in Welfare Institution is considerably high. We should pay more attention attention to cure and prevention of elderly depressive disorder in Welfare Institution, strengthen the psychological nursing and sentimental care, in order to improve their quality of life and play the key role of social caring for elders.

  8. Variations in the Incidence of Schizophrenia: Data Versus Dogma

    OpenAIRE

    McGrath, John J.

    2006-01-01

    The schizophrenia research community has shared a belief that the incidence of schizophrenia shows little variation. This belief is related to the dogma that schizophrenia affects all individuals equally, regardless of sex, race, or nationality. However, there is now robust evidence that the incidence of schizophrenia is characterized by substantial variability. There is prominent variation in the incidence of schizophrenia between sites. The incidence of schizophrenia is significantly higher...

  9. 根管治疗期间急症的发生程度与相关因素分析%A clinical evaluation of endodontic interappointment emergencies: incidence, severity and related factors

    Institute of Scientific and Technical Information of China (English)

    张颖; 潘倩茹; 黄绮凌; 郑耀斌; 黄世光

    2012-01-01

    Objective The present study was performed to investigate the incidence, severity and related factors of endodontic interappointment emergencies (EIAE) and flare up index (FUI). Mothods Two hundred and four patients attending for endodontic therapy in Hunan Wantwant Hospital were randomly assigned to either double flared technique or crown down technique procedure group. In group A, 101 teeth were instrumented with double flared technique;In group B, 103 teeth were instrumented with crown down technique. The related factors were recorded, including age, gender, tooth position, pulpal and periapical status, pre-operative pain, sinus and the symptoms occurred 1 week after root canal instrumentation. Results The incidence of EIAE observed in 204 teeth was 13.24%. Twenty two endodontic EIAE (21.78%) were recorded in double flared technique group compared to 5(4.85%) EIAE in crown down technique group. The EIAE incidence in double flared technique group was significantly higher than that in crown down technique group (P0.05). Conclusion Crown down technique has been shown to be a safe and effective alternative to double flared technique. The presences of a periapical lesion and the pre-operative pain or without sinus were the most important predictors of EIAE during root canal therapy.%目的 分析根管治疗期间急症(EIAE)发生率、急性发作指数(FUI)及相关因素.方法 按纳入标准选取204例在湖南旺旺医院口腔科就诊需行根管治疗的患牙,随机分成两组,A组101例患牙采用双敞法制备根管;B组103例患牙采用根向深入法制备根管.记录相关数据,如患者年龄、性别、牙位、患牙治疗前状况(包括牙髓及根尖周状况、治疗前疼痛、窦道)及根管器械制备后1周内出现的症状.结果 204例患牙EIAE的发生率为13.24%(27/204),FUI值为3.51±1.36.双敞法组EIAE的发生率(21.78%)明显高于根向深入法组(4.85%),二者差异有统计学意义(P<0.01).

  10. Analysis of related factors and incidence of hyperglycemia in patients with schizophrenia%精神分裂症患者的高血糖发生率及相关因素分析

    Institute of Scientific and Technical Information of China (English)

    曾荟宇

    2015-01-01

    Objective To Analyze the related factors and incidence of hyperglycemia in patients with schizophrenia. Methods Clinical data of 336 cases with schizophrenia treated in our hospital from January to December 2013 were retrospectively analyzed,the incidence of hyperglycemia was counted,and related factors of hyperglycemia in patients with schizophrenia was analyzed. Results 42 cases (12.5%) of 336 patients combined with hyperglycemia,and 15 cases (4.5%) were diagnosed with diabetes.Negative symptom scores of patients with hyperglycemia was 28.2±6.9,higher than national norm (22.18±7.92),the difference was significant (P<0.01).Patients combined with hyperglycemia was older than that of patients without hyperglycemia,course of disease was longer,and negative symptom score was higher than that of patients without hyperglycemia,the difference was significant (P<0.01).Multi factor analysis showed that the course of disease,negative symptoms,hyperglycemia was associated with hyperglycemia (P<0.05 or P<0.01). Conclusion The inci-dence of hyperglycemia in patients with schizophrenia is high,and the negative symptom is obvious.The longer the dura-tion,the higher negative symptom,the greater the risk of hyperglycemia.%目的:分析精神分裂症患者高血糖的发生率以及相关因素。方法回顾性分析2013年1~12月在本院治疗的336例精神分裂症患者的临床资料,统计高血糖的发生率,并分析与精神分裂症患者合并高血糖的相关因素。结果336例患者中有42例(12.5%)合并高血糖,15例(4.5%)确诊为糖尿病。合并高血糖的患者阴性症状评分为(28.2±6.9)分,显著高于国内常模的(22.18±7.92)分,差异有统计学意义(P<0.01)。合并高血糖患者年龄显著大于未合并高血糖患者,病程显著长于未合并高血糖患者,阴性症状得分显著高于未合并高血糖患者,差异有统计学意义(P<0.01)。多因素回归分析显示,病程、阴性症状评分与

  11. Incidence and relative risk of adverse events of special interest in patients with castration resistant prostate cancer treated with CYP-17 inhibitors: A meta-analysis of published trials.

    Science.gov (United States)

    Roviello, Giandomenico; Sigala, Sandra; Danesi, Romano; Re, Marzia Del; Bonetta, Alberto; Cappelletti, Maria Rosa; Zanotti, Laura; Bottini, Alberto; Generali, Daniele

    2016-05-01

    Abiraterone acetate and orteronel are two CYP-17 inhibitors that have been studied in prostate cancer. They have shown relevant toxicities, including fluid retention/oedema, hypokalaemia, hypertension, liver function test abnormalities and cardiac events. The goal of this study was to determine the risk of special adverse events related to CYP- 17 inhibitor in patients with metastatic castration-resistant prostate cancer (CRCP). Summary data from four randomized phase III trials comparing CYP-17 inhibitors and prednisone versus placebo and prednisone in metastatic CRCP patients were meta-analysed. Pooled risk ratios (RRs) for the risk of all-grade and grade 3-4 adverse events of special interest were calculated. Data from 4916 patients (2849 in the AA experimental arm; 2067 in the control arm) were analysed. The incidence of grade 3-4 adverse events was never more than 10% of the patients. However, compared with placebo, the CYP-17 inhibitor significantly increased the all-grade events of hypertension (RR=1.53; 95% CI=1.3-1.8; pevents, hypokalaemia (RR=4.23; 95% CI=1.28-13.99; p=0.02) and cardiac disorders (RR=1.55; 95% CI=1.18-2.05; p=0.002). A lot of adverse events such as hypertension, hypokalaemia, cardiac disorders and liver function test abnormalities are increased during CYP-17 inhibitor based therapy. Strict monitoring of these side effects should be considered during CYP- 17 inhibitor therapy in prostate cancer patients.

  12. Comparing electronic news media reports of potential bioterrorism-related incidents involving unknown white powder to reports received by the United States Centers for Disease Control and Prevention and the Federal Bureau of Investigation: U.S.A., 2009-2011.

    Science.gov (United States)

    Fajardo, Geroncio C; Posid, Joseph; Papagiotas, Stephen; Lowe, Luis

    2015-01-01

    There have been periodic electronic news media reports of potential bioterrorism-related incidents involving unknown substances (often referred to as "white powder") since the 2001 intentional dissemination of Bacillus anthracis through the U.S. Postal System. This study reviewed the number of unknown "white powder" incidents reported online by the electronic news media and compared them with unknown "white powder" incidents reported to the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Federal Bureau of Investigation (FBI) during a 2-year period from June 1, 2009 and May 31, 2011. Results identified 297 electronic news media reports, 538 CDC reports, and 384 FBI reports of unknown "white powder." This study showed different unknown "white powder" incidents captured by each of the three sources. However, the authors could not determine the public health implications of this discordance.

  13. Congestion with incidents

    DEFF Research Database (Denmark)

    Fosgerau, Mogens

    2010-01-01

    This paper considers the impact of random delays during a repeatedly occurring demand peak in a congested facility, such as an airport or an urban road. Congestion is described in the form of a dynamic queue using the Vickrey bottleneck model and assuming Nash equilibrium in departure times. Every...... period an incident may occur at a random time, temporarily reducing the bottleneck capacity to zero. The paper gives some properties of Nash equilibrium and the social optimum as well as a pretty good welfare improving tolling scheme....

  14. Semantic Language and Tools for Reporting Human Factors Incidents Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Incidents related to impaired human performance in space operations can be caused by environmental conditions, situational challenges, and operational deficiencies....

  15. 急性脑卒中偏瘫患者的抑郁发病率及相关因素分析%Study on the Incidence of Depression and Related Factors of Acute Stroke Patients with Hemiplegia

    Institute of Scientific and Technical Information of China (English)

    邓强

    2014-01-01

    目的:观察急性脑卒中偏瘫患者抑郁的发生,分析影响急性脑卒中偏瘫患者发生抑郁的因素。方法选取2009-12-2012-12在我院住院治疗的急性脑卒中偏瘫患者194例为研究对象。统计194例患者抑郁的发生率,对抑郁和非抑郁患者进行神经功能缺损和日常生活能力评估,分析急性脑卒中偏瘫患者发生抑郁的影响因素。结果 SDS评分≥50分78例,SAS评分≥50分81例。单纯焦虑18例,单纯抑郁15例,焦虑伴抑郁63例。抑郁患者的日常生活能力评分和神经功能缺损评分与非抑郁患者相比差异具有统计学意义( P<0.05)。根据抑郁发生率影响因素的单因素分析显示,病变部位、病程以及NDS可能与抑郁发生有关。Logistic回归分析显示,病变部位、病程及NDS与抑郁发生具有相关性。结论病变部位、病程及NDS会影响急性脑卒中偏瘫患者发生抑郁,应该采取恰当的预防措施降低抑郁的发生率。%Objective To observe and analyze the Incidence of Depression and Related Factors of Patients with Hemiplegia caused by Acute Stroke.Methods 194 patients with hemiplegia admitted to our hospital from December 2009 to December 2012 were selected as the object of study. The incidence of depression in the 194 cases of patients was analyzed ,evaluation of neural function defect and activities of daily living in patients with depression and non-depression were conducted ,and the influencing factors of depression were analyzed.Results Patients with SDS score ≥ 50 points took up 78 cases ,those with SAS score ≥50 points were 81 cases. Patients with mere anxiety were 18 cases ,and 15 cases with depression ,63 cases with anxiety and de-pression. Scores of activities of daily living and neurologic impairment scores of patients with depression were significantly dif-ferent from those of non depressive patients ,and the difference was statistically significant (P<0.05). The

  16. 重庆市城市农村儿童肥胖发病率及相关因素的分析%Analysis on childhood obesity incidences between urban and rural in Chongqing and its related factors

    Institute of Scientific and Technical Information of China (English)

    秦怡玲; 熊丰; 赵勇; 朱岷; 罗雁红; 王付丽; 曾燕; 吴利平; 马勤香

    2013-01-01

    目的:了解重庆地区儿童肥胖发病率及肥胖相关因素的城乡差异.方法:按照整群抽样方法,抽取重庆市86所城乡中小学校共77 411名学龄儿童,测量身高、体质量,并计算体质指数(body mass index,BMI).按照分层整群抽样方法再从中抽取2所城市学校和3所农村学校共4 400名儿童行肥胖影响因素问卷调查,按照BMI法判定肥胖,将肥胖儿童和正常儿童设为肥胖组和对照组,对儿童肥胖相关因素进行多因素logistic回归分析,并比较肥胖危险因素城乡差异.结果:(1)重庆地区学龄儿童总体肥胖率8.23%,城市9.70%,农村5.32%,城市高于农村(P<0.000 1).(2)肥胖相关因素logistic回归分析结果显示,共13个因素与城市儿童肥胖相关,其中出生体质量,肉食、油炸食品、饮料、零食摄入频率,母亲吸烟及肥胖家族史是危险因素,母乳喂养、蔬菜摄入频率及补充维生素是保护因素;共8个因素与农村儿童肥胖相关,其中出生体质量、油炸食品、奶制品、零食摄入频率,父母BMI是危险因素,母乳喂养是保护因素.(3)城市儿童肉食、油炸食品、奶制品摄入频率高于农村,母亲吸烟比例高于农村,家族肥胖史比例高于农村,母乳喂养率低于农村(P<0.05).结论:重庆地区儿童肥胖率城市高于农村,引起差异的主要因素为母亲吸烟、母孕期营养、6月龄前喂养方式、儿童青少年生活方式及肥胖家族史.控制儿童肥胖城市重点应倡导母孕期戒烟,加强母乳喂养,控制儿童肉食、油炸食品、含糖饮料、零食摄入;农村儿童肥胖率虽低于城市,但增速大于城市,应改善儿童饮食方式,控制油炸食品、奶制品、零食摄入,预防儿童肥胖.%Objective:To study the incidences of childhood obesity between urban and rural area in Chongqing and its related factors.Methods:According to the cluster sampling method,a total of 77 411 school-age children aged 6 to

  17. Analysis on relative factors of the incidence and development diabetic retinopathy%糖尿病视网膜病变发生发展的相关因素分析

    Institute of Scientific and Technical Information of China (English)

    张建文; 马丽; 马凤仙

    2013-01-01

    可作为DR发生发展的预示指标。%AIM:To investigate the relative factors of the incidence and development of diabetic retinopathy ( DR) . METHODS: The retinopathy of the 631 patients with type 2 diabetes mellitus ( T2DM ) was examined by ophthalmoscopy and fundus fluorescein angiography ( FFA) , and the relative factors which possibly associate with the incidence and development of DR were collected. RESULTS: There were 205 patients with DR, the morbidity rate of DR was 32.5% ( 95%CI:28.82%-36.15%) , the nonproliferative diabetic retinopathy ( NPDR ) and proliferative diabetic retinopathy ( PDR ) were 134 cases occupying 21.2% ( 95%CI: 18.04%-24.44%) and 71 cases occupying 11.3%(95%CI:8.78%-13.72%) of the patients with DR, respectively. Univariate analysis showed that income, living environment, whether treatment by insulin, combined with diabetic nephropathy ( DN) , combined with diabetic peripheral neuropathy ( DPN), hold on exercise, course of diabetes, fasting plasma glucose ( FPG ) , 2 hours'postprandial plasma glucose ( 2hPG ), glycosylated hemoglobin A1c ( HbA1c ), systolic blood pressure ( SBP) , total cholesterol ( TC) , urinary albumin excretion rate (UAER), serum creatinine (SCr), and blood urea nitrogen ( BUN ) were significant different among the patients without DR, the patients with NPDR and the patients with PDR ( P<0.05 or P<0.01 ).Multivariate ordinal Logistic regression analysis showed that the incidence and development of DR increased in patients with longer course of diabetes, high HbA1c, high UAER and without exercise, and decreased in patients without DN and DPN (P<0.05 or P<0.01). CONCLUSION:There was a high morbidity rate of DR in patients with patients with type 2 diabetes.The longer course of diabetes, high HbA1c, and without exercise were the independent development factors of DR, whether combined with DN, combined with DPN and UAER were indices for the incidence and development of DR.

  18. Critical Incidents in Internal Relationships

    OpenAIRE

    Voima, PÀivi

    2000-01-01

    Critical incidents have had an important role in service quality and service management research. The focus of critical-incident studies has gradually shifted from separate acts and episodes towards relationships, and even switching from one relationship to another. The Critical Incident Technique has mainly been used when studying the service sector, concentrating on the customer's perception of critical incidents. Although some studies have considered the perceptions of employees important,...

  19. Incident Management: Process into Practice

    Science.gov (United States)

    Isaac, Gayle; Moore, Brian

    2011-01-01

    Tornados, shootings, fires--these are emergencies that require fast action by school district personnel, but they are not the only incidents that require risk management. The authors have introduced the National Incident Management System (NIMS) and the Incident Command System (ICS) and assured that these systems can help educators plan for and…

  20. Racist Incident-Based Trauma

    Science.gov (United States)

    Bryant-Davis, Thema; Ocampo, Carlota

    2005-01-01

    Racist incidents are potentially traumatizing forms of victimization that may lead to increased psychiatric and psychophysiological symptoms in targets. The magnitude of the problem of racist incidents in the United States is difficult to estimate; however, data from several sources permit the inference that the prevalence of racist incidents,…

  1. Incidence and mortality rates in breast, corpus uteri, and ovarian cancers in Poland (1980–2013: an analysis of population-based data in relation to socio-economic changes

    Directory of Open Access Journals (Sweden)

    Banas T

    2016-09-01

    Full Text Available Tomasz Banas,1 Grzegorz Juszczyk,2 Kazimierz Pitynski,1 Dorota Nieweglowska,1 Artur Ludwin,1 Aleksandra Czerw2 1Department of Gynecology and Oncology, Jagiellonian University Medical College, Krakow, 2Faculty of Health Science, Medical University of Warsaw, Warsaw, Poland Objectives: This study aimed to analyze incidence and mortality trends in breast cancer (BC, corpus uteri cancer (CUC, and ovarian cancer (OC in Poland in the context of sociodemographic changes.Materials and methods: Incidence and mortality data (1980–2013 were retrieved from the Polish National Cancer Registry, while socioeconomic data (1960–2013 were obtained from the World Bank. Age-standardized incidence and mortality rates were calculated by direct standardization, and join-point regression was performed to describe trends using the average annual percentage change (AAPC.Results: A significant decrease in birth and fertility rates and a large increase in gross domestic product were observed together with a decrease in the total mortality rate among women, as well as an increase in life expectancy for women. A large, significant increase in BC incidence was observed (AAPC1980–1990 2.14, AAPC1990–1996 4.71, AAPC1996–2013 2.21, with a small but significant decrease in mortality after a slight increase (AAPC1980–1994 0.52, AAPC1994–2013 −0.66. During the period 1980–2013, a significant increase in CUC incidence (AAPC1980–1994 3.7, AAPC1994–2013 1.93 was observed, with an initial mortality-rate reduction followed by a significant increase (AAPC1980–2006 −1.12, AAPC2006–2013 3.74. After the initial increase of both OC incidence and mortality from 1994, the incidence rate decreased significantly (AAPC1980–1994 2.98, AAPC1994–2013 −0.49, as did the mortality rate (AAPC1980–1994 0.52, AAPC1994–2013 −0.66.Conclusion: After 1994, a decrease in OC incidence was found, while the incidence of BC and CUC continued to increase. A reduction in

  2. Statement of nuclear incidents

    International Nuclear Information System (INIS)

    Eight incidents were reported. Three mothers (two at BNFL's Sellafield Reprocessing Plant and one at Berkeley Nuclear Laboratories) had been contaminated and received more than the annual dose limit. At the Winfrith Atomic Energy Establishment, Cs124 and Cs137 had been washed off the outside of a flask onto the ground. At the BNFL Springfields works a discharge of a solution of natural uranium had occurred to the site foul drain. At the Drigg storage and disposal site a leak from a storage tank was reported. In the other three cases no radioactive release occurred. There was a loose coupling on a tiebar of a fuel stringer at Heysham-I reactor, water beneath a pipeline discharging from Harwell Laboratory was found not to be contaminated and at Dungeness-B a fuel assembly was dropped to the bottom of the reactor during refuelling. (UK)

  3. The incidence of hospital-treated occupational hand injuries

    DEFF Research Database (Denmark)

    Skov, O

    1994-01-01

    Previous studies have shown that young men have the highest frequency of occupational hand injuries. This study investigated their incidence and severity in relation to age and sex. For occupational hand injuries in general the estimated incidence rate was 17.1 per 1,000 person years. The incidence...... was found to be higher among men than women in all age groups below 60 years. The incidence for minor injuries declines with increasing age, but the rates for significant injuries are independent of age. The higher incidence rate for minor injuries among young patients could be real, but it could also...

  4. Related factors of Keshan disease on incidence influence of residents in endemic area%克山病发病相关因素对病区居民患病情况的影响

    Institute of Scientific and Technical Information of China (English)

    相有章; 王秀红; 张文静; 屈福荣; 刘源; 张文明; 王静

    2012-01-01

    目的 观察克山病发病相关因素对克山病患病情况的影响,为病因研究提供科学依据.方法 选择莒县、沂水、平邑、邹城4个克山病病区县(市)的克山病发病村设立监测点,自1990年起连续观察20年,每5年为一阶段.每阶段对同一组人群连续观察5年,第1、3、5年对全部观察对象进行临床查体和描记心电图,可疑病人X线胸部后前位摄片,诊断符合“克山病诊断标准”.同时采集头发、小麦、玉米、红薯干(地瓜干),应用荧光法测定硒含量.调查经济收入和人均占有粮食.结果 20年共观察人群15 368例/次,克山病年均检出率3.12%,潜在型为2.68%,慢型0.44%,慢型检出率并呈逐年下降趋势.采集发样800份,小麦766份,玉米658份和地瓜干668份.发硒水平逐年升高(P<0.05~0.01),1997年后达到硒适宜地区水平,粮食硒水平基本恒定.经济收入与人均占有粮食显著增加,从1990年的535.8元/人、254.6 kg/人逐年增加至2009年的3200.0元/人、683.0 kg/人.结论 克山病病情稳定,慢型克山病病情呈逐年下降态势,硒营养状况改善是影响病情变化的重要因素.%Objective To observe the related factors of Keshan disease ( KSD) on incidence influence of residents in endemic area in order to provide the scientific basis of etiology study of Keshan disease. Methods To choose the epidemic villages in KSD area of Juxian, Yishui, Pingyi, Zoucheng counties were set up observing points. Every five years was made as a stage since 1990.3 to 14 - year - old residents and over 14 - year - old suspicious patients were selected as surveillance subjects from first stage to third stage but all residents were selected as surveillance subjects in fourth stage. The same group of surveillance subjects in each stage were observed consecutively for 5 years. Surveillance contents included physical checkup, electrocardiogram( ECG) and X - ray. At the same time samples of hair, wheat

  5. Comparative Incidence of Conformational, Neurodegenerative Disorders.

    Directory of Open Access Journals (Sweden)

    Jesús de Pedro-Cuesta

    Full Text Available The purpose of this study was to identify incidence and survival patterns in conformational neurodegenerative disorders (CNDDs.We identified 2563 reports on the incidence of eight conditions representing sporadic, acquired and genetic, protein-associated, i.e., conformational, NDD groups and age-related macular degeneration (AMD. We selected 245 papers for full-text examination and application of quality criteria. Additionally, data-collection was completed with detailed information from British, Swedish, and Spanish registries on Creutzfeldt-Jakob disease (CJD forms, amyotrophic lateral sclerosis (ALS, and sporadic rapidly progressing neurodegenerative dementia (sRPNDd. For each condition, age-specific incidence curves, age-adjusted figures, and reported or calculated median survival were plotted and examined.Based on 51 valid reported and seven new incidence data sets, nine out of eleven conditions shared specific features. Age-adjusted incidence per million person-years increased from ≤1.5 for sRPNDd, different CJD forms and Huntington's disease (HD, to 1589 and 2589 for AMD and Alzheimer's disease (AD respectively. Age-specific profiles varied from (a symmetrical, inverted V-shaped curves for low incidences to (b those increasing with age for late-life sporadic CNDDs and for sRPNDd, with (c a suggested, intermediate, non-symmetrical inverted V-shape for fronto-temporal dementia and Parkinson's disease. Frequently, peak age-specific incidences from 20-24 to ≥90 years increased with age at onset and survival. Distinct patterns were seen: for HD, with a low incidence, levelling off at middle age, and long median survival, 20 years; and for sRPNDd which displayed the lowest incidence, increasing with age, and a short median disease duration.These results call for a unified population view of NDDs, with an age-at-onset-related pattern for acquired and sporadic CNDDs. The pattern linking age at onset to incidence magnitude and survival might

  6. Cancer incidence among Nordic airline cabin crew.

    Science.gov (United States)

    Pukkala, Eero; Helminen, Mika; Haldorsen, Tor; Hammar, Niklas; Kojo, Katja; Linnersjö, Anette; Rafnsson, Vilhjálmur; Tulinius, Hrafn; Tveten, Ulf; Auvinen, Anssi

    2012-12-15

    Airline cabin crew are occupationally exposed to cosmic radiation and jet lag with potential disruption of circadian rhythms. This study assesses the influence of work-related factors in cancer incidence of cabin crew members. A cohort of 8,507 female and 1,559 male airline cabin attendants from Finland, Iceland, Norway and Sweden was followed for cancer incidence for a mean follow-up time of 23.6 years through the national cancer registries. Standardized incidence ratios (SIRs) were defined as ratios of observed and expected numbers of cases. A case-control study nested in the cohort (excluding Norway) was conducted to assess the relation between the estimated cumulative cosmic radiation dose and cumulative number of flights crossing six time zones (indicator of circadian disruption) and cancer risk. Analysis of breast cancer was adjusted for parity and age at first live birth. Among female cabin crew, a significantly increased incidence was observed for breast cancer [SIR 1.50, 95% confidence interval (95% CI) 1.32-1.69], leukemia (1.89, 95% CI 1.03-3.17) and skin melanoma (1.85, 95% CI 1.41-2.38). Among men, significant excesses in skin melanoma (3.00, 95% CI 1.78-4.74), nonmelanoma skin cancer (2.47, 95% CI 1.18-4.53), Kaposi sarcoma (86.0, 95% CI 41.2-158) and alcohol-related cancers (combined SIR 3.12, 95% CI 1.95-4.72) were found. This large study with complete follow-up and comprehensive cancer incidence data shows an increased incidence of several cancers, but according to the case-control analysis, excesses appear not to be related to the cosmic radiation or circadian disruptions from crossing multiple time zones.

  7. Cancer incidence among firefighters

    DEFF Research Database (Denmark)

    Pukkala, Eero; Martinsen, Jan Ivar; Weiderpass, Elisabete;

    2014-01-01

    OBJECTIVES: Firefighters are potentially exposed to a wide range of known and suspected carcinogens through their work. The objectives of this study were to examine the patterns of cancer among Nordic firefighters, and to compare them with the results from previous studies. METHODS: Data for this......OBJECTIVES: Firefighters are potentially exposed to a wide range of known and suspected carcinogens through their work. The objectives of this study were to examine the patterns of cancer among Nordic firefighters, and to compare them with the results from previous studies. METHODS: Data...... for this study were drawn from a linkage between the census data for 15 million people from the five Nordic countries and their cancer registries for the period 1961-2005. SIR analyses were conducted with the cancer incidence rates for the entire national study populations used as reference rates. RESULTS......: A total of 16 422 male firefighters were included in the final cohort. A moderate excess risk was seen for all cancer sites combined, (SIR=1.06, 95% CI 1.02 to 1.11). There were statistically significant excesses in the age category of 30-49 years in prostate cancer (SIR=2.59, 95% CI 1.34 to 4...

  8. Delay Adjusted Incidence Infographic

    Science.gov (United States)

    This Infographic shows the National Cancer Institute SEER Incidence Trends. The graphs show the Average Annual Percent Change (AAPC) 2002-2011. For Men, Thyroid: 5.3*,Liver & IBD: 3.6*, Melanoma: 2.3*, Kidney: 2.0*, Myeloma: 1.9*, Pancreas: 1.2*, Leukemia: 0.9*, Oral Cavity: 0.5, Non-Hodgkin Lymphoma: 0.3*, Esophagus: -0.1, Brain & ONS: -0.2*, Bladder: -0.6*, All Sites: -1.1*, Stomach: -1.7*, Larynx: -1.9*, Prostate: -2.1*, Lung & Bronchus: -2.4*, and Colon & Rectum: -3/0*. For Women, Thyroid: 5.8*, Liver & IBD: 2.9*, Myeloma: 1.8*, Kidney: 1.6*, Melanoma: 1.5, Corpus & Uterus: 1.3*, Pancreas: 1.1*, Leukemia: 0.6*, Brain & ONS: 0, Non-Hodgkin Lymphoma: -0.1, All Sites: -0.1, Breast: -0.3, Stomach: -0.7*, Oral Cavity: -0.7*, Bladder: -0.9*, Ovary: -0.9*, Lung & Bronchus: -1.0*, Cervix: -2.4*, and Colon & Rectum: -2.7*. * AAPC is significantly different from zero (p<.05). Rates were adjusted for reporting delay in the registry. www.cancer.gov Source: Special section of the Annual Report to the Nation on the Status of Cancer, 1975-2011.

  9. Taken with Surprise: Critical Incidents in Teaching

    Science.gov (United States)

    Pui-Lan, Kwok; Brown, William P.; Delamarter, Steve; Frank, Thomas E.; Marshall, Joretta L.; Menn, Esther; Riggs, Marcia Y.

    2005-01-01

    This collection of essays tackles thorny questions related to critical incidents in teaching. By using different pedagogical methods and techniques, each author provokes creative thinking about how to address specific concerns common to teaching. The authors demonstrate that the teaching and learning process must make room for--if not…

  10. Changing incidence and improved survival of gliomas

    NARCIS (Netherlands)

    Ho, Vincent K. Y.; Reijneveld, Jaap C.; Enting, Roeline; Bienfait, Henri P.; Robe, Pierre; Baumert, Brigitta G.; Visser, Otto

    2014-01-01

    BACKGROUND: Tumours of the central nervous system (CNS) represent a relatively rare but serious health burden. This study provides insight into the incidence and survival patterns of gliomas in the Netherlands diagnosed in adult patients during the time period 1989-2010, with a focus on glioblastoma

  11. 1988至2014年青岛市某石棉厂石棉相关疾病发病情况%The incidence of asbestos-related diseases about on asbestos enterprises in Qingdao from 1988 to 2014

    Institute of Scientific and Technical Information of China (English)

    宋平平; 王艳; 孙建岭; 高燕; 刘娟; 陈艳霞

    2016-01-01

    239 patients lose their lives,motality is 38.74%.Conclusion There is a high incidence of a disease about asbestos related disease in the asbestos products factory,it has close relationship with asbestos exposure time,the dust concentration of workplace and type of work et al.Asbestos related diseases are still the main problem in Qingdao.

  12. Financial Incentives for Teen Parents to Stay in School. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2006

    2006-01-01

    Financial incentives for teen parents are components of state welfare programs intended to encourage enrollment, attendance, and completion of high school as a means of increasing employment and earnings and reducing welfare dependence. The incentives take the form of bonuses and sanctions to the welfare grant related to school enrollment,…

  13. 45 CFR 2518.110 - What are the functions of a Service-Learning Clearinghouse?

    Science.gov (United States)

    2010-10-01

    ...) Conduct research and evaluations concerning service-learning; (c)(1) Provide leadership development and... participants; and (2) Provide training to persons who can provide the leadership development and training... programs, innovative youth skills curricula related to service-learning, and service-learning projects;...

  14. SU-E-P-07: Retrospective Analysis of Incident Reports at a Radiology Department: Feedback From Incident Reporting System

    International Nuclear Information System (INIS)

    Purpose: To provide an overview of reported incidents that occurred in a radiology department and to describe the most common causal source of incidents. Methods: Incident reports from the radiology department at the University of the Ryukyus Hospital between 2008 and 2013 were collected and analyzed retrospectively. The incident report form contains the following items, causal factors of the incident and desirable corrective actions to prevent recurrence of similar incidents. These items allow the institution to investigate/analyze root causes of the incidents and suggest measures to be taken to prevent further, similar incidents. The ‘causal factors of the incident’ item comprises multiple selections from among 24 selections and includes some synonymous selections. In this study, this item was re-categorized into four causal source types: (i) carelessness, (ii) lack of skill or knowledge, (iii) deficiencies in communication, and (iv) external factors. Results: There were a total of 7490 incident reports over the study period and 276 (3.7%) were identified as originating from the radiology department. The most frequent causal source type was carelessness (62%). The other three types showed similar frequencies (10–14%). The staff members involved in incidents indicate three predominant desirable corrective actions to prevent or decrease the recurrence of similar incidents. These are ‘improvement in communication’ (24%), ‘staff training/education’ (19%), and ‘daily medical procedures’ (22%), and the most frequent was ‘improvement in communication’. Even though the most frequent causal factor was related to carelessness, the most desirable corrective action indicated by the staff members was related to communication. Conclusion: Our finding suggests that the most immediate causes are strongly related to carelessness. However, the most likely underlying causes of incidents would be related to deficiencies in effective communication. At our

  15. SU-E-P-07: Retrospective Analysis of Incident Reports at a Radiology Department: Feedback From Incident Reporting System

    Energy Technology Data Exchange (ETDEWEB)

    Kakinohana, Y; Toita, T; Heianna, J; Murayama, S [School of medicine, University of the Ryukyus, Nishihara-cho, Okinawa (Japan)

    2015-06-15

    Purpose: To provide an overview of reported incidents that occurred in a radiology department and to describe the most common causal source of incidents. Methods: Incident reports from the radiology department at the University of the Ryukyus Hospital between 2008 and 2013 were collected and analyzed retrospectively. The incident report form contains the following items, causal factors of the incident and desirable corrective actions to prevent recurrence of similar incidents. These items allow the institution to investigate/analyze root causes of the incidents and suggest measures to be taken to prevent further, similar incidents. The ‘causal factors of the incident’ item comprises multiple selections from among 24 selections and includes some synonymous selections. In this study, this item was re-categorized into four causal source types: (i) carelessness, (ii) lack of skill or knowledge, (iii) deficiencies in communication, and (iv) external factors. Results: There were a total of 7490 incident reports over the study period and 276 (3.7%) were identified as originating from the radiology department. The most frequent causal source type was carelessness (62%). The other three types showed similar frequencies (10–14%). The staff members involved in incidents indicate three predominant desirable corrective actions to prevent or decrease the recurrence of similar incidents. These are ‘improvement in communication’ (24%), ‘staff training/education’ (19%), and ‘daily medical procedures’ (22%), and the most frequent was ‘improvement in communication’. Even though the most frequent causal factor was related to carelessness, the most desirable corrective action indicated by the staff members was related to communication. Conclusion: Our finding suggests that the most immediate causes are strongly related to carelessness. However, the most likely underlying causes of incidents would be related to deficiencies in effective communication. At our

  16. 中国HIV感染孕产妇早产及其影响因素分析%Incidence of and related risk factors on preterm delivery among HIV-infected pregnant women in China

    Institute of Scientific and Technical Information of China (English)

    王爱玲; 王潇滟; 窦丽霞; 王芳; 王前; 乔亚萍; 苏敏; 金曦

    2015-01-01

    目的 了解目前我国HIV感染孕产妇早产的流行情况并探讨其相关影响因素.方法 数据来源于2013年我国预防艾滋病母婴传播管理信息系统.对HIV感染孕产妇的人口学特征、妊娠情况、HIV相关情况等变量进行分析,计算早产发生率并探讨相关影响因素.结果 纳入分析的3 913例HIV感染孕产妇中有336例发生早产,早产率为8.6%.分析发现我国HIV感染孕产妇早产与年龄、民族、文化程度、人口流动状态、有无妊娠高血压、是否为多胎妊娠、孕期随访次数等因素之间存在关联,差异有统计学意义(P<0.05);与吸毒感染HIV者相比,其他途径感染者早产率低(aOR=0.562,95%CI:0.360~0.879).在14 ~ 27孕周和在<14孕周就已开始使用抗反转录病毒药物(ARV)的孕产妇同妊娠期间从未使用过ARV药物的孕产妇相比早产发生危险性增加,aOR直分别为1.712(95%CI:1.196~ 2.451)和1.862(95%CI:1.261~ 2.749).结论 早产是我国HIV感染孕产妇常见不良妊娠结局之一.HIV感染孕产妇早产不仅与传统危险因素相关,还与HIV感染途径及孕期ARV药物服用情况相关.%Objective To measure the incidence rates of preterm delivery in HIV-infected pregnant women and to explore related potential risk factors.Methods Data from 'Information System of Prevention of Mother-to-child Transmission of HIV Management in China,2013' was used in the study.Information regarding demographic characteristics,pregnancy,HIV relevant situations and pregnancy outcomes related to these HIV-infected pregnant women,were extracted and analyzed.Incidence of preterm delivery was calculated with related potential risk factors explored.Results 3 913 HIV-infected pregnant women were involved in this study,including 336 of them having undergone preterm deliveries (8.6%).Results from univariate and multivariate analyses showed that preterm delivery was associated with factors as:maternal age

  17. Incidence and related factors of postoperative delirium in lumbar spine surgeries of older patients%老年患者腰椎术后谵妄发病率及相关因素分析

    Institute of Scientific and Technical Information of China (English)

    柳根哲; 陈江; 徐林; 李春根; 孙旗; 李德魁; 焦勇

    2012-01-01

    [目的]对老年患者腰椎术后谵妄的发病率及相关因素进行分析.[方法]回顾性分析2009年1月~2011年6月在本院因腰椎退行性疾病接受手术的114例患者(≥70岁)的病例资料,将术后谵妄发病与既往病史、手术时间、术中输血、输血量、融合节段数以及实验室数据等因素进行相关性研究.[结果]腰椎术后共有13例患者出现谵妄,发病率为11.4%,既往有呼吸系统疾病的患者术后谵妄发病率较高(P=0.043),与对照组相比,谵妄组患者术后血红蛋白(P<0.001)、术前/术后红细胞压积(P=0.013/0.005)及术后白蛋白(P =0.002)均偏低.[结论]术后谵妄高发于老年患者中既往有呼吸系统疾病的患者,同时术后血红蛋白、红细胞压积、白蛋白偏低与术后谵妄发病有明显的相关性.%[Objective] To analyze the incidence and related factors of postoperative delirium in older patients after lumbar spine surgery. [ Methods ] Total 114 patients over 70 years who underwent lumbar operative for degenerative lumbar disease from January 2009 to April 2010 were selected. We analyzed the relation between postoperative delirium and such factors as operative time, intraoperative blood loss and transfusion, comorbidity and laboratory data. [Results] Postoperative delirium were found in 13 patients (11.4% ) . There were significant relationships between postoperative delirium and comorbidity such as pulmonary diseases and hemoglobin (P < 0.001) , hematocrit ( P < 0.05 ) levels and albumin level after surgery was significantly lower than in control group (P =0. 002) . Oswestry disability index was improved from 51. 7% to 22. 6% in delirium group and from 49. 6% to 23. 9% in control group. Hospitalization period was significantly longer in delirium group. [ Conclusion] Postoperative delirium is of great concern in older patients. History of pulmonary diseases, and low hemoglobin, hematocrit and albumin levels after surgery are

  18. Security incidents on the Internet, 1989--1995

    Energy Technology Data Exchange (ETDEWEB)

    Howard, J.D.

    1995-12-31

    This paper presents an analysis of trends in Internet security based on an investigation of 4,299 Internet security-related incidents reported to the CERT{reg_sign} Coordination Center (CERT{reg_sign}/CC) from 1989 through 1995. Prior to this research, knowledge of actual Internet security incidents was limited and primarily anecdotal. This research: (1) developed a taxonomy to classify Internet attacks and incidents, (2) organized, classified, and analyzed CERT{reg_sign}/CC incident records, (3) summarized the relative frequency of the use of tools and vulnerabilities, success in achieving access, and results of attacks, (4) estimated total Internet incident activity, (5) developed recommendations for Internet users and suppliers, and (6) developed recommendations for future research. With the exception of denial-of-service attacks, security incidents were found to be increasing at a rate less than Internet growth. Estimates showed that most, if not all, severe incidents were reported to the CERT{reg_sign}/CC, and that more than one out of three above average incidents (in terms of duration and number of sites) were reported. Estimates also indicated that a typical Internet site was involved in, at most, around one incident (of any kind) per year, and a typical Internet host in, at most, around one incident in 45 years. The probability of unauthorized privileged access was around an order of magnitude less likely. As a result, simple and reasonable security precautions should be sufficient for most Internet users.

  19. Incidência e severidade do "furo de bala" em folhas da ameixeira sob doses de nitrogênio e potássio Incidence and severity of 'shot hole' in plum´s leaves related into nitrogen and potassium doses

    OpenAIRE

    Inês Tutida; Louise Larissa May-De Mio; Antonio Carlos Vargas Motta; Joel Maurício Corrêa da Rosa

    2007-01-01

    A produção integrada (PI) vem suprir uma demanda crescente de frutos de qualidade, garantir segurança alimentar, produção com qualidade ambiental e rastreabilidade. Na visão da PI, as práticas da adubação e do controle de doenças estão intimamente relacionadas; no entanto, tem sido negligenciadas e pouco estudadas, principalmente para a doença "furo de bala" (Wilsonomyces carpophilus) em folhas de ameixeira (Prunus salicina). O objetivo deste trabalho foi avaliar a incidência e severidade des...

  20. Effects of nutrition-related factors and indicators on incidence of pressure ulcer in elderly patients%营养相关指标对老年患者压疮发生率的影响

    Institute of Scientific and Technical Information of China (English)

    王艳; 陈慧敏; 袁芳; 蒋德川

    2011-01-01

    目的 探讨营养相关指标对老年患者压疮发生率的影响,为制定针对性预防措施提供依据.方法 采集559例年龄≥60岁的消化科住院老年患者的年龄、卧床时间、疾患状况、消化道反应、人体测量指标、实验室指标、饮食类型与营养支持途径、每日服用处方药种类及压疮资料,行χ2检验和非条件Logistic回归分析.结果 卧床时间、食欲减退或吞咽困难、血清白蛋白、小腿围、营养支持途径、饮食类型、体质量7项是老年患者发生压疮的影响因素,其OR值分别为12.932、4.680、3.006、2.677、2.166、1.759和1.407.结论 卧床、营养不良及所导致症状是老年住院患者发生压疮的促成因素,应采取针对性干预措施改善不良指标,预防住院老年患者发生压疮.%Objective To explore the effects of nutrition-related factors and indicators on incidence of pressure ulcer in elderly patients, and to provide a basis for medical staff to carry out effective preventive measures.Methods The clinical data of 559 patients aged 60 years or older and hospitalized in division of gastroenterology were analyzed retrospectively, including age, the time span of being confined to bed rest, diseases they had, gastrointestinal symptoms, anthropometric indices, lab test results, types of diet,routes of nutritional support, daily medication, and conditions of pressure ulcer.The above mentioned factors and indicators were analyzed by using the Chi-square test and unconditional logistic regression analysis.Results Such factors and indicators as time span of being confined to bed rest, anorexia or dysphagia, level of serum albumin, the thigh circumference, the routes of nutritional support, types of diet and body weight resulted in pressure ulcer in elderly inpatients, with the OR values being 12.932, 4.680,3.006, 2.677, 2.166, 1.759 and 1.407 respectively.Conclusion Being confined to bed rest, malnutrition and related symptoms

  1. Incident reporting in general practice

    NARCIS (Netherlands)

    Zwart, D.L.M.

    2011-01-01

    Background and aim An incident reporting procedure (IRP) is an important part of patient safety management in healthcare. Currently, patient safety efforts are mainly guided by the ‘systems approach’: incidents, defined as ‘unintended or unexpected events which could have led or did lead to harm for

  2. True incidence of vestibular schwannoma?

    DEFF Research Database (Denmark)

    Stangerup, Sven-Eric; Tos, Mirko; Thomsen, Jens;

    2010-01-01

    The incidence of diagnosed sporadic unilateral vestibular schwannomas (VS) has increased, due primarily to more widespread access to magnetic resonance imaging.......The incidence of diagnosed sporadic unilateral vestibular schwannomas (VS) has increased, due primarily to more widespread access to magnetic resonance imaging....

  3. 原发性震颤患者伴发抑郁的发生率及相关因素%Incidence of essential tremor associated with depression and related factors

    Institute of Scientific and Technical Information of China (English)

    陈菊萍; 毛成洁; 胡伟东; 刘建芳; 陈冬勤; 刘春风

    2009-01-01

    Objective To study the incidence of depression in essential tremor (ET) and associated factors. Methods Depression in 62 ET patients and 60 healthy subjects as control was evaluated by means of Hamilton Depression Scale ( HAMD ) , as well as Fahn-Tolosa-Marin Tremor Rating Scale (TRS) and Pittsburgh Sleep Quality Index (PSQI). Results Fifty-three point two percent(33/62) of ET patients and 11.7% (7/60) of healthy subjects were found to have at least mildly depression (HAMD score of 8 or higher), 35. 5% (22/62) of ET patients and 8. 3% (5/60) of healthy subjects fell into the mildly-to-mederately depression (HAMD score between 8 and 20 ), 17.7% (11/62) of ET patients and 3.3% (2/60) of healthy subjects were classified into moderately-to-severely depressed range (HAMD score between 21 and 35). There were statistical differences in ET group and healthy subjects group (X2= 23.898, 13.043, 6.649, all P <0.01). Additionally, there were statistical differences in anxiety/ somatization (t=-6.747, P<0.01), cognitive impairment (t=-2.017, P=0.05), block(t= -4.145, P<0.01), sleep disorders (t=-4.500, P<0.01) and despair (t=-3.591, P<0.01) between depression group and non-depression group. There were marked differences in PSQI total score ( t =-3.196, P=0.003 ), subjective sleep ( F1, t=-3.037, P=0.004), quality sleep latency (F2, t= -4.674, P<0.01) and sleep disturbances (F5, t=-2.594, P=0.013 ) between depression disorder group and non-depression disorder group. Meanwhile, the score of TRS, PSQI and sex were closely correlated with HAMD (β=0.589, P=0.000 ;β=0.469,P=0.000 ;β=0.256, P=0.027 ). Conclusions The incidence of depression is high in ET. Manifestation of depression are anxiety, reduced interest in work, sleep disorders, retardneas, inferiority complex, etc. The degree of symptoms relates to the severity of ET, sleep quality and gender.%目的 研究原发性震颤(ET)患者抑郁的发生率及相关的因素.方法 应用汉密尔顿抑郁量表(HAMD)对62

  4. Cardiovascular disease incidence and survival

    DEFF Research Database (Denmark)

    Byberg, Stine; Agyemang, Charles; Zwisler, Ann Dorthe;

    2016-01-01

    Studies on cardiovascular disease (CVD) incidence and survival show varying results between different ethnic groups. Our aim was to add a new dimension by exploring the role of migrant status in combination with ethnic background on incidence of-and survival from-CVD and more specifically acute...... and differences in incidence were assessed by Poisson regression and stratified by sex. Survival differences were assessed by Cox regression using all-cause and cause-specific mortality as outcome. Male refugees had significantly lower incidence of CVD (RR = 0.89; 95 % CI 0.85-0.93) and stroke (IRR = 0.62; 95...... significantly lower incidence of CVD, AMI and stroke. All-cause and cause-specific survival after CVD, AMI and stroke was similar or significantly better for migrants compared to Danish-born, regardless of type of migrant (refugee vs. family-reunified) or country of origin. Refugees are disadvantaged in terms...

  5. Relativity

    CERN Document Server

    Brewster, Hilary D

    2009-01-01

    The theory of relativity has become a cornerstone of modern physics. Over the course of time it has been scrutinized in a multitude of experiments and has always been verified with high accuracy. The correctness of this theory can no longer be called into question. Right after its discovery by Albert Einstein in 1905, special relativity was only gradually accepted because it made numerous predictions contradicting common sense, fervently castigated by Einstein, and also defied experiment for too long a time. It was only with the advent of particle or high energy physics that matter could be ac

  6. Relativity

    CERN Document Server

    Einstein, Albert

    2013-01-01

    Time magazine's ""Man of the Century"", Albert Einstein is the founder of modern physics and his theory of relativity is the most important scientific idea of the modern era. In this short book, Einstein explains, using the minimum of mathematical terms, the basic ideas and principles of the theory that has shaped the world we live in today. Unsurpassed by any subsequent books on relativity, this remains the most popular and useful exposition of Einstein's immense contribution to human knowledge.With a new foreword by Derek Raine.

  7. 寻常型银屑病皮损湿疹样改变的发生率及其相关因素%Observation of the incidence and related factors of the psoriasis vulgaris patients

    Institute of Scientific and Technical Information of China (English)

    陆明敏; 史飞; 蔡瑞康; 白明明

    2015-01-01

    Objective To investigate the incidence and related factors of the psoriasis vulgaris patients with eczema appearrance. Methods The patients with psoriasis vulgaris were collected from Air Force General Hospital dermatology clinic between December 2013 and April 2014; statistical scale was established and the image acquisition equipment to record the basic information and gross and microscopic lesion was used; the SPSS 16.0 software and Excel software were made into use for data analysis. Results The 241 cases of patients with psoriasis vulgaris included 137 male cases and 104 female cases. Among the total of 122 cases of patients with eczema appearance change, the rate was 50.6%, this change of patients in gender, age, family history, course of diseases, season had no statistically significant differences; however, the skin type, different degree of pruritus and disease staging difference were statistically significant. Conclusion Patients with psoriasis vulgaris have strong itching feeling or have dry skin, or they are in progressive stage, the skin lesion will easily have eczema-change. In the early treatment, the itching drugs and humectant should be paid greatly attention to. The medicine should be used jointly to improve curative effect, also to promote skin lesions to disappear.%目的:探讨寻常型银屑病皮损出现湿疹样改变的发生率及相关因素。方法收集2013年12月—2014年4月就诊于空军总医院皮肤科门诊的寻常型银屑病患者241例,通过制订病例调查表记录患者信息和病情变化情况,利用图像采集设备记录皮损图像信息,应用SPSS16.0软件和Excel软件进行数据分析。结果241例中,出现湿疹样改变122例,发生率为50.6%;出现湿疹样改变与未出现湿疹样改变的患者在皮肤类型、瘙痒评分及疾病分期方面差异具有统计学意义(P<0.05);在性别、年龄、家族史、病程及皮损形态上差异无统计学意义(P>0.05

  8. Detection of incidents and events in urban networks

    NARCIS (Netherlands)

    Thomas, T.; Berkum, van E.C.

    2009-01-01

    Events and incidents are relatively rare, but they often have a negative impact on traffic. Reliable travel demand predictions during events and incident detection algorithms are thus essential. The authors study link flows that were collected throughout the Dutch city of Almelo. We show that reliab

  9. Incidence of abacavir hypersensitivity reactions in euroSIDA

    DEFF Research Database (Denmark)

    Bannister, Wendy P; Friis-Møller, Nina; Mocroft, Amanda;

    2008-01-01

    BACKGROUND: The aim of the study was to investigate the incidence of abacavir-related hypersensitivity reaction (HSR) and associated deaths in EuroSIDA HIV-1-infected patients. METHODS: Poisson regression models were developed to compare incidence of abacavir discontinuation according to the line...

  10. The incidence of gonorrhea in an abortion population

    NARCIS (Netherlands)

    Querido, L.; Haspels, A.A.

    1980-01-01

    The incidence of gonorrhea was investigated in an abortion population. A total of 1021 women participated in this study. Three asymptomatic cases of gonorrhea were detected. None of these women had had gonorrhea before or had a previous abortion. No relation was found between the incidence of gonorr

  11. Cancer incidence among Danish seafarers

    DEFF Research Database (Denmark)

    Kærlev, Linda; Hansen, Johnny; Lyngbeck Hansen, Hans;

    2005-01-01

    .19 to 1.32) for men and 1.07 (95% CI 0.95 to 1.20) for women. This was mainly due to an excess of cancer of the larynx, lung, tongue, mouth, pharynx, oesophagus, pancreas, kidney, urinary bladder, colon, and bone as well as skin melanomas among men (the three latter borderline significantly increased...... extensively in ships. The aim of this study was to study cancer morbidity among Danish seafarers in relation to type of ship and job title. METHODS: A cohort of all Danish seafarers during 1986-1999 (33,340 men; 11,291 women) registered by the Danish Maritime Authority with an employment history was linked...... with the nationwide Danish Cancer Registry and followed up for cancer until the end of 2002. The number of person years at risk was 517,518. Standardised incidence ratios (SIR) were estimated by use of the corresponding national rates. RESULTS: The SIR of all cancers combined was higher than expected: 1.26 (95% CI 1...

  12. Fuzzy Logic for Incidence Geometry

    Science.gov (United States)

    2016-01-01

    The paper presents a mathematical framework for approximate geometric reasoning with extended objects in the context of Geography, in which all entities and their relationships are described by human language. These entities could be labelled by commonly used names of landmarks, water areas, and so forth. Unlike single points that are given in Cartesian coordinates, these geographic entities are extended in space and often loosely defined, but people easily perform spatial reasoning with extended geographic objects “as if they were points.” Unfortunately, up to date, geographic information systems (GIS) miss the capability of geometric reasoning with extended objects. The aim of the paper is to present a mathematical apparatus for approximate geometric reasoning with extended objects that is usable in GIS. In the paper we discuss the fuzzy logic (Aliev and Tserkovny, 2011) as a reasoning system for geometry of extended objects, as well as a basis for fuzzification of the axioms of incidence geometry. The same fuzzy logic was used for fuzzification of Euclid's first postulate. Fuzzy equivalence relation “extended lines sameness” is introduced. For its approximation we also utilize a fuzzy conditional inference, which is based on proposed fuzzy “degree of indiscernibility” and “discernibility measure” of extended points. PMID:27689133

  13. Epidemiology of Eating Disorders: Incidence, Prevalence and Mortality Rates

    OpenAIRE

    Smink, Frédérique R. E.; van Hoeken, Daphne; Hoek, Hans W.

    2012-01-01

    Eating disorders are relatively rare among the general population. This review discusses the literature on the incidence, prevalence and mortality rates of eating disorders. We searched online Medline/Pubmed, Embase and PsycINFO databases for articles published in English using several keyterms relating to eating disorders and epidemiology. Anorexia nervosa is relatively common among young women. While the overall incidence rate remained stable over the past decades, there has been an increas...

  14. Decreasing incidence rates of bacteremia

    DEFF Research Database (Denmark)

    Nielsen, Stig Lønberg; Pedersen, C; Jensen, T G;

    2014-01-01

    BACKGROUND: Numerous studies have shown that the incidence rate of bacteremia has been increasing over time. However, few studies have distinguished between community-acquired, healthcare-associated and nosocomial bacteremia. METHODS: We conducted a population-based study among adults with first......-acquired, 50.0 for healthcare-associated and 66.7 for nosocomial bacteremia. During 2000-2008, the overall incidence rate decreased by 23.3% from 254.1 to 198.8 (3.3% annually, p ...) and the incidence rate of nosocomial bacteremia decreased by 28.9% from 82.2 to 56.0 (4.2% annually, p

  15. Incidents/accidents classification and reporting in Statoil

    International Nuclear Information System (INIS)

    met. - The data quality for the more serious incidents (5% of the total number of incidents registered) has improved. - The improved handling of incidents has contributed to more reliable and accurate HSE indicators at a corporate level. - More user friendly codes in place for incident registration (based on MTO methodology). - The revised matrix gives distinct criteria with respect to which investigation level to be initiated for a specific incident. All activities related to handling of undesirable incidents have been summarised and illustrated on a two-sided plastic form, incorporating both the categorisation matrix and the activity flowchart

  16. Incidents/accidents classification and reporting in Statoil.

    Science.gov (United States)

    Berentsen, Rune; Holmboe, Rolf H

    2004-07-26

    quality for the more serious incidents (5% of the total number of incidents registered) has improved, the improved handling of incidents has contributed to more reliable and accurate HSE indicators at a corporate level, more user friendly codes in place for incident registration (based on MTO methodology), the revised matrix gives distinct criteria with respect to which investigation level to be initiated for a specific incident. All activities related to handling of undesirable incidents have been summarised and illustrated on a two-sided plastic form, incorporating both the categorisation matrix and the activity flowchart (see Figs. 1 and 4). PMID:15231361

  17. Incidence of multiple myeloma in Nagasaki City

    International Nuclear Information System (INIS)

    In order to observe the incidence of multiple myeloma in the population of Nagasaki City from 1973 to 1982, and to assess any influence caused by A-bomb exposure, 85 cases of myeloma have been collected and analysed. Informatively, 48 cases of this number were A-bomb survivors. Among the middle-aged cases, the crude incidence rates of myeloma in the exposed group were found to be higher than those in the non-exposed group. Further, the relative risk of myeloma was higher in A-bomb survivors and this tendency become more pronounced in the those who were within 2 km of the epicenter of the blast. The age-adjusted relative risk in male and female A-bomb survivors was 1.59 and 1.68 respectively, but no significant differences were noted. (author)

  18. Using mortality data to estimate radiation effects on breast cancer incidence.

    OpenAIRE

    Hoel, D. G.; Dinse, G E

    1990-01-01

    In this paper we combine Japanese data on radiation exposure and cancer mortality with U.S. data on cancer incidence and lethality to estimate the effects of ionizing radiation on cancer incidence. The analysis is based on the mathematical relationship between the mortality rate and the incidence and lethality rates, as well as on statistical models that relate Japanese incidence rates to U.S. incidence rates and radiation risk factors. Our approach assumes that the risk of death from causes ...

  19. Estimation of Incident Wave Height

    DEFF Research Database (Denmark)

    Frigaard, Peter; Helm-Petersen, J.

    1994-01-01

    The paper is the results found by Aalborg University in the calculations of the incident wave heights hm0 and the reflection coefficients α from the LIP-MAST investigations in the Vinje-Basin during May to July 1994....

  20. The NEA incident reporting system

    International Nuclear Information System (INIS)

    The Nuclear Energy Agency (NEA) Incident Reporting System (IRS) was established in 1980 in order to exchange operating experience gained in thermal nuclear power plants and to facilitate proper feedback of this experience to benefit nuclear regulatory authorities, utilities and manufacturers as well as to provide additional guidance for safety research programmes. The purpose of the system is to collect and disseminate sufficiently detailed information on incidents of safety significance in nuclear power plants, as soon as practicable, and feed back appropriate conclusions from such incidents. The exchange of information, in the form of reports, is supplemented by a database storage system designed to facilitate the process of identifying relevant reported incidents for specific studies. The NEA-IRS is an efficient and effective way of collecting and distributing information about operational experience of nuclear power plants on an international scale. (author)

  1. Idiot Savants: Rate of Incidence

    Science.gov (United States)

    Hill, A. Lewis

    1977-01-01

    A survey of 300 public residential facilities for the mentally retarded revealed a .06 percent incidence rate for idiot savants, persons of low intelligence who possess an unusually high skill in some special task. (CL)

  2. Thyroid cancer incidence in Corsica. 1998 - 2006

    International Nuclear Information System (INIS)

    In France, Corsica appears to be one of the most exposed regions to the fallout from the Chernobyl accident. Taking into account the scientific knowledge at that time, it was decided to focus studies on thyroid cancers. A study was carried out in order to estimate thyroid cancer incidence in Corsica for the periods 1998-2001 and 2002-2006. The study identified incident thyroid cancer cases between 1998 and 2006 among residents in Corsica. Data were collected using information from the hospitals (PMSI) and the local health insurance funds (ALD). Cases were validated through medical records before inclusion in the study. Over the period of study, 342 cases of thyroid cancer, rather women and relatively young patients, were identified in Corsica. Incidence rate of the thyroid cancer was high, but stable among men, and with a slight increase among women, particularly between 2002 and 2006. However, incidence rate and clinical characteristics of thyroid cancer in Corsica are not exceptional and are similar to those in other French districts. (authors)

  3. Worldwide Increasing Incidences of Cutaneous Malignant Melanoma

    Directory of Open Access Journals (Sweden)

    Dianne E. Godar

    2011-01-01

    Full Text Available The incidence of cutaneous malignant melanoma (CMM has been increasing at a steady rate in fair-skinned populations around the world for decades. Scientists are not certain why CMM has been steadily increasing, but strong, intermittent UVB (290–320 nm exposures, especially sunburn episodes, probably initiate, CMM, while UVA (321–400 nm passing through glass windows in offices and cars probably promotes it. The CMM incidence may be increasing at an exponential rate around the world, but it definitely decreases with increasing latitude up to ~50°N where it reverses and increases with the increasing latitude. The inversion in the incidence of CMM may occur because there is more UVA relative to UVB for most of the year at higher latitudes. If windows, allowing UVA to enter our indoor-working environment and cars, are at least partly responsible for the increasing incidence of CMM, then UV filters can be applied to reduce the rate of increase worldwide.

  4. Spatial Distribution of Black Bear Incident Reports in Michigan.

    Directory of Open Access Journals (Sweden)

    Jamie E McFadden-Hiller

    Full Text Available Interactions between humans and carnivores have existed for centuries due to competition for food and space. American black bears are increasing in abundance and populations are expanding geographically in many portions of its range, including areas that are also increasing in human density, often resulting in associated increases in human-bear conflict (hereafter, bear incidents. We used public reports of bear incidents in Michigan, USA, from 2003-2011 to assess the relative contributions of ecological and anthropogenic variables in explaining the spatial distribution of bear incidents and estimated the potential risk of bear incidents. We used weighted Normalized Difference Vegetation Index mean as an index of primary productivity, region (i.e., Upper Peninsula or Lower Peninsula, primary and secondary road densities, and percentage land cover type within 6.5-km2 circular buffers around bear incidents and random points. We developed 22 a priori models and used generalized linear models and Akaike's Information Criterion (AIC to rank models. The global model was the best compromise between model complexity and model fit (w = 0.99, with a ΔAIC 8.99 units from the second best performing model. We found that as deciduous forest cover increased, the probability of bear incident occurrence increased. Among the measured anthropogenic variables, cultivated crops and primary roads were the most important in our AIC-best model and were both positively related to the probability of bear incident occurrence. The spatial distribution of relative bear incident risk varied markedly throughout Michigan. Forest cover fragmented with agriculture and other anthropogenic activities presents an environment that likely facilitates bear incidents. Our map can help wildlife managers identify areas of bear incident occurrence, which in turn can be used to help develop strategies aimed at reducing incidents. Researchers and wildlife managers can use similar mapping

  5. Urbanisation and the incidence of eating disorders.

    OpenAIRE

    Son, G.E. van; Hoeken, D. van; Bartelds, A.I.M.; Furth, E.F. van; Hoek, H.W.

    2006-01-01

    The link between degree of urbanisation and a number of mental disorders is well established. Schizophrenia, psychosis and depression are known to occur more frequently in urban areas. In our primary care-based study of eating disorders, the incidence of bulimia nervosa showed a dose response relation with degree of urbanisation and was five times higher in cities than in rural areas. Remarkably, anorexia nervosa showed no association with urbanisation. We conclude that urbanlife is a potenti...

  6. NRC Incident-Response Plan

    International Nuclear Information System (INIS)

    The Nuclear Regulatory Commission (NRC) regulates civilian nuclear activities to protect the public health and safety and to preserve environmental quality. An Incident Response Plan had been developed and has now been revised to reflect current Commission policy. NUREG-0728, Rev. 1 assigns responsibilities for responding to any potentially threatening incident involving NRC licensed activities and for assuring that the NRC will fulfill its statutory mission. This report has also been reproduced for staff use as NRC Manual Chapter 0502

  7. The Incidence of Congenital Malformation and the Analysis of Related Factors in Changzhi%山西某地区近年先天畸形发生情况及相关因素分析

    Institute of Scientific and Technical Information of China (English)

    贾书花; 王炯; 王改琴; 张旭东; 牛香兰; 田云; 霍小蕾

    2015-01-01

    目的::了解长治地区近年来先天性畸形的发生情况,探讨畸形发生的相关因素。方法:对8967例新生儿中151例先天畸形进行分析。结果:本次统计先天畸形发生率为168.40/万;畸形发生较高的依次为:神经管畸形、多并指(趾),唇、腭裂。未补充叶酸畸形发生率高于叶酸补充者(P <0.01),≥35岁产妇先天畸形儿发生率高于<35岁者(P <0.01);农村先天畸形发生率高于城市(P <0.01)。结论:先天畸形的发生除与普遍认知的叶酸缺乏相关外,还和父亲生活习惯、医疗条件、卵子及宫内环境、婚源等因素有关。因此,应重视评估父亲对后代的影响,防范有可能诱发畸形的其它因素,以避免先天畸形的发生。%Objective:To understand the incidence of congenital malformation of the region and its influencing factors and to explore the causes and preventive measures of deformity.Methods:151 congenital malformations among 8 967 newborns were analyzed in Obstetrics Department in HeJi Hospital Affiliated to Changzhi Medical College from January 2004 to December 2013.Results:The incidence of congenital malformation was 168.40/million.Higher incidence of malformations was:neural tube defects,finger (toe),cleft lip and cleft palate.Without the supplement of folic acid,the incidence rate of malformation was higher than those with the supplement of folic acid(P <0.01).The maternal congenital deformity rate of those≥35 years old was significantly higher than those<35 years old (P <0.01).The incidence of rural congenital malformation was higher than that of the city (P <0.01).Conclusion:Other than the well-known lack of folic acid,the occurrence of congenital malformation was also associated with the living habits of the father,medical conditions,the source of eggs and intrauterine environment,marriage and other factors.Therefore,the effects of the father to the future generations should be evaluated and paid

  8. Prediction of dengue incidence using search query surveillance.

    Directory of Open Access Journals (Sweden)

    Benjamin M Althouse

    2011-08-01

    Full Text Available BACKGROUND: The use of internet search data has been demonstrated to be effective at predicting influenza incidence. This approach may be more successful for dengue which has large variation in annual incidence and a more distinctive clinical presentation and mode of transmission. METHODS: We gathered freely-available dengue incidence data from Singapore (weekly incidence, 2004-2011 and Bangkok (monthly incidence, 2004-2011. Internet search data for the same period were downloaded from Google Insights for Search. Search terms were chosen to reflect three categories of dengue-related search: nomenclature, signs/symptoms, and treatment. We compared three models to predict incidence: a step-down linear regression, generalized boosted regression, and negative binomial regression. Logistic regression and Support Vector Machine (SVM models were used to predict a binary outcome defined by whether dengue incidence exceeded a chosen threshold. Incidence prediction models were assessed using r² and Pearson correlation between predicted and observed dengue incidence. Logistic and SVM model performance were assessed by the area under the receiver operating characteristic curve. Models were validated using multiple cross-validation techniques. RESULTS: The linear model selected by AIC step-down was found to be superior to other models considered. In Bangkok, the model has an r² = 0.943, and a correlation of 0.869 between fitted and observed. In Singapore, the model has an r² = 0.948, and a correlation of 0.931. In both Singapore and Bangkok, SVM models outperformed logistic regression in predicting periods of high incidence. The AUC for the SVM models using the 75th percentile cutoff is 0.906 in Singapore and 0.960 in Bangkok. CONCLUSIONS: Internet search terms predict incidence and periods of large incidence of dengue with high accuracy and may prove useful in areas with underdeveloped surveillance systems. The methods presented here use freely available

  9. Cancer incidence in Italian contaminated sites

    Directory of Open Access Journals (Sweden)

    Pietro Comba

    2014-06-01

    Full Text Available INTRODUCTION. The incidence of cancer among residents in sites contaminated by pollutants with a possible health impact is not adequately studied. In Italy, SENTIERI Project (Epidemiological study of residents in National Priority Contaminated Sites, NPCSs was implemented to study major health outcomes for residents in 44 NPCSs. METHODS. The Italian Association of Cancer Registries (AIRTUM records cancer incidence in 23 NPCSs. For each NPCSs, the incidence of all malignant cancers combined and 35 cancer sites (coded according to ICD-10, was analysed (1996-2005. The observed cases were compared to the expected based on age (5-year period,18 classes, gender, calendar period (1996-2000; 2001-2005, geographical area (North-Centre and Centre-South and cancer sites specific rates. Standardized Incidence Ratios (SIR with 90% Confidence Intervals were computed. RESULTS. In both genders an excess was observed for overall cancer incidence (9% in men and 7% in women as well as for specific cancer sites (colon and rectum, liver, gallbladder, pancreas, lung, skin melanoma, bladder and Non Hodgkin lymphoma. Deficits were observed for gastric cancer in both genders, chronic lymphoid leukemia (men, malignant thyroid neoplasms, corpus uteri and connective and soft-tissue tumours and sarcomas (women. DISCUSSION. This report is, to our knowledge, the first one on cancer risk of residents in NPCSs. The study, although not aiming to estimate the cancer burden attributable to the environment as compared to occupation or life-style, supports the credibility of an etiologic role of environmental exposures in contaminated sites. Ongoing analyses focus on the interpretation of risk factors for excesses of specific cancer types overall and in specific NPCSs in relation to the presence of carcinogenic pollutants.

  10. SEXUALLY TRANSMITTED DISEASES: INCIDENCE AND DISTRIBUTION

    Institute of Scientific and Technical Information of China (English)

    王千秋

    1996-01-01

    The incidence of sexually transmitted diseases(STDs) increased from 26. 04 per 10000O in 1987 to 104. 81 per 100 000 in 1993 in selected areas of the country. Gonorrhea is by far the most common STD but its constituent ratio declined because of a rapid increase of nongonococcal uretheritis and genital warts during most recent years. The incidence of syphilis is relatively low and cases of congenital infection are noted. The wide spread of resistant Neisseria gonorrhaeae infection gives a challenge to the therapeutical and control strategies of STDs. Sexually transmitted Chlamydia trachomatis infections, an important cause of urethritis, cervicitis and pelvic inflammatory disease, is becoming common in uur country. Attention has been drawn on viral hepatitis in their means of transmission by sexually behaviors, and also, on the homosexuals, assumed to be the high risk group to catch STDs. Coordinated national efforts to control STDs in China have been taken.

  11. Significant incidents in nuclear fuel cycle facilities

    International Nuclear Information System (INIS)

    In contrast to nuclear power plants, events in nuclear fuel cycle facilities are not well documented. The INES database covers all the nuclear fuel cycle facilities; however, it was developed in the early 1990s and does not contain information on events prior to that. The purpose of the present report is to collect significant events and analyze them in order to give a safety related overview of nuclear fuel cycle facilities. Significant incidents were selected using the following criteria: release of radioactive material or exposure to radiation; degradation of items important to safety; and deficiencies in design, quality assurance, etc. which include criticality incidents, fire, explosion, radioactive release and contamination. This report includes an explanation, where possible, of root causes, lessons learned and action taken. 4 refs, 4 tabs

  12. The incidence of fragility fractures in Italy.

    Science.gov (United States)

    Ratti, Chiara; Vulcano, Ettore; La Barbera, Giuseppe; Canton, Gianluca; Murena, Luigi; Cherubino, Paolo

    2013-10-01

    Osteoporosis can significantly impact on the risk of developing a fracture. Thus, fragility fractures represent a challenge for health professionals and decision makers of the twenty-first century. The aim of this work is to review the literature concerning osteoporotic fractures in Italy in terms of incidence, rate of hospitalization, relative risk of a new fragility fracture, and costs for the national health system. It was estimated that the costs of treating proximal femur fragility fractures in 2002 summed up to 1 billion Euros. The number of fragility fractures in Italy was calculated as follows: 91.494 hip fractures, 61.009 clinical vertebral fractures, 57.401 humeral fragility fractures, and 94.045 forearm/wrist fragility fractures. The incidence of fragility fractures in Italy is very high, and osteoporosis is the leading cause of morbidity in the Italian population. PMID:24046040

  13. The Nanjing Incident: Recent Research and Trends

    Directory of Open Access Journals (Sweden)

    ASKEW, David

    2002-04-01

    Full Text Available The Nanjing Incident remains a highly controversial episode in Sino-Japanese relations. It remains so controversial that a neutral definition has yet to be agreed upon. However, most would perhaps agree on the following. Sadly for the historian, however, the Nanjing Incident is also emerging as a fundamental keystone in the construction of the modern Chinese national identity. As a result, the historian's interest in and analysis of this event can be interpreted as an attack on the contemporary Chinese identity, while any demonstrated interest in Nanjing can be viewed in some circles in Japan as Japan bashing or self-flagellation. In this environment, the historian's struggle to maintain objectivity can quickly fall victim to the demands of contemporary politics.

  14. Risk - hazardous incident - communication 1

    International Nuclear Information System (INIS)

    Terms such as 'risk', 'hazardous incident', and 'communication' have become major catchwords in discussions about present-day problems, and may be reduced to a common denominator: disaster. Such an association, however, is inappropriate, as the concept indicated by the term 'risk' for instance covers a wide scale of possible danger. Even the term 'hazardous incident' describes events or conditions that are very different in terms of possible danger, let alone disastrous effects. The discrepancy to be observed between the facts and the public perception usually is due to the fact that people have little insight into the complex of problems involved, and to insufficient communication between the world of experts and the general public. The contributions to this publication present information and discuss a variety of solution sets to improve the communication problems in the context of the problem area of 'risk - hazardous incident - communication'. (orig./CB)

  15. Risk - hazardous incident - communication 2

    International Nuclear Information System (INIS)

    It is difficult to develop an objective approach to risks and effects of a hazardous incident that would be acceptable to the community at large. It is a matter of fact that there is great dissimilarity in the way various social groups perceive and define the risks of a particular technology, or the effects of hazardous incidents, sometimes they have even contrary opinions. Hence, open communication is seriously hampered, which in turn aggravates the problems encountered in this context. This second volume of the publication dealing with the problem area of 'risk - hazardous incident - communication' is intended to reveal patterns of the recurrent process which impedes communication, and to bridge the gaps between the various 'styles' of risk perception and definition. (orig./CB)

  16. Recent waterway incidents around dams

    Energy Technology Data Exchange (ETDEWEB)

    Rowat, L. [Ontario Power Generation Inc., Niagara Falls, ON (Canada)

    2009-07-01

    This presentation discussed recent waterway incidents around dams. Several case histories were presented, including a man who drowned when he slipped from the top of the South Idaho Power Plant Spillway in June 3 2004; 2 brothers who drowned near a spillway in Watson Minnesota, in June, 2004; a jet-skier who plunged to his death after ramping the 50 foot Brasfield Dam, in Virginia in June, 2004; a couple whose boat on Lake Austin was swept up against the sluicegate; an angler who drowned at a dam in Bridgeville, Delaware; a man who drowned swimming below a dam in San Marcos, Texas in April, 2005; and a fisherman who drowned at Logan Martin Dam in Birmingham, Alabama in April, 2005. A list of examples of fatalities at dams in 2004 and international incidents at dams from 2005 and 2006 to 2008 were also provided. Examples of Canadian incidents at dams were also listed. figs.

  17. Automatic Analysis of Critical Incident Reports: Requirements and Use Cases.

    Science.gov (United States)

    Denecke, Kerstin

    2016-01-01

    Increasingly, critical incident reports are used as a means to increase patient safety and quality of care. The entire potential of these sources of experiential knowledge remains often unconsidered since retrieval and analysis is difficult and time-consuming, and the reporting systems often do not provide support for these tasks. The objective of this paper is to identify potential use cases for automatic methods that analyse critical incident reports. In more detail, we will describe how faceted search could offer an intuitive retrieval of critical incident reports and how text mining could support in analysing relations among events. To realise an automated analysis, natural language processing needs to be applied. Therefore, we analyse the language of critical incident reports and derive requirements towards automatic processing methods. We learned that there is a huge potential for an automatic analysis of incident reports, but there are still challenges to be solved. PMID:27139389

  18. Age-Related Hearing Loss

    Science.gov (United States)

    ... hearing loss. Here are the most common ones: Styles of hearing aids Source: NIH/NIDCD Hearing aids ... list of organizations, contact: NIDCD Information Clearinghouse 1 Communication Avenue Bethesda, MD 20892-3456 Toll-free Voice: ( ...

  19. Serious Incident Management in Australia

    Science.gov (United States)

    Ellis, Ike; Thorley-Smith, Sara

    2007-01-01

    As part of its efforts to ensure school safety, the government of New South Wales, Australia, has developed simulation exercises to better prepare principals to manage serious incidents, in collaboration with police. This article describes two initiatives implemented across NSW. The exercises provide principals in both secondary and primary…

  20. [Incidence of cancer in Navarre].

    Science.gov (United States)

    Ardanaz, E; Moreno, C; Pérez de Rada Arístegui, M E; Ezponda, C; Navaridas, N

    2004-01-01

    Between 1998 and 2000 an annual average of 3,303 cases of invasive cancer were registered in Navarre, 58% of them in men. If we except non melanoma skin tumours, the annual number of cases was 2,495, with gross incidence rates of 559 and 372 per 100,000 in men and women, and rates adjusted to the world population of 312 and 203 per 100,000 respectively. Amongst men, the four most frequently diagnosed tumoural localisations were the prostate, lung, colorectal and bladder, accounting for 57% of all cases. The most notable due to their frequency amongst women were tumours of the breast, colorectal, uterus body and ovary, accounting for 54% of all cases. With respect to the five year period from 1993 to 1997, the global incidence of cancer in the three year period from 1998 to 2000 has increased 4.2% in men and 7.4% in women. The incidence of lung cancer and non-Hodgkin lymphomas in both sexes and of breast cancer in women and prostate cancer in men are notable. There continues to be a fall in the incidence rates of stomach cancer in both sexes, following the tendency begun in the 1970s. PMID:15644889

  1. The critical incident inventory: characteristics of incidents which affect emergency medical technicians and paramedics

    Directory of Open Access Journals (Sweden)

    Halpern Janice

    2012-08-01

    Full Text Available Abstract Background Emergency medical technicians (EMTs and paramedics experience critical incidents which evoke distress and impaired functioning but it is unknown which aspects of incidents contribute to their impact. We sought to determine these specific characteristics by developing an inventory of critical incident characteristics and testing their relationship to protracted recovery from acute stress, and subsequent emotional symptoms. Methods EMT/paramedics (n = 223 completed a retrospective survey of reactions to an index critical incident, and current depressive, posttraumatic and burnout symptoms. Thirty-six potential event characteristics were evaluated; 22 were associated with peritraumatic distress and were retained. We assigned inventory items to one of three domains: situational, systemic or personal characteristics. We tested the relationships between (a endorsing any domain item and (b outcomes of the critical incident (peritraumatic dissociation, recovery from components of the Acute Stress Reaction and depressive, posttraumatic, and burnout symptoms. Analyses were repeated for the number of items endorsed. Results Personal and situational characteristics were most frequently endorsed. The personal domain had the strongest associations, particularly with peritraumatic dissociation, prolonged distressing feelings, and current posttraumatic symptoms. The situational domain was associated with peritraumatic dissociation, prolonged social withdrawal, and current posttraumatic symptoms. The systemic domain was associated with peritraumatic dissociation and prolonged irritability. Endorsing multiple characteristics was related to peritraumatic, acute stress, and current posttraumatic symptoms. Relationships with outcome variables were as strong for a 14-item inventory (situational and personal characteristics only as the 22-item inventory. Conclusions Emotional sequelae are associated most strongly with EMT/paramedics’ personal

  2. Cancer incidence study in Mesa County, Colorado

    International Nuclear Information System (INIS)

    In November of 1982 the Colorado Department of Health completed an epidemiologic investigation of leukemia, multiple myeloma, and cancers of the lung, stomach, pancreas and colon in Mesa County, Colorado for the years 1970 to 1979. This investigation was performed in response to a concern that the presence of uranium mill tailings in some Mesa County homes presents a potential cancer hazard. The results of the investigation show that the incidence of multiple myeloma, colon, stomach and pancreatic cancer are not above expected rates. The incidence of leukemia is not above expected rates for the entire study period, 1970 to 1979. The incidence of lung cancer appears elevated when compared to the The Third National Cancer Survey data for Colorado but lower than expected when compared to Surveillance, Epidemiology and End Results data. To further examine the leukemia and lung cancer incidence findings, a case/control study was conducted. The controls consisted of colon, stomach and pancreatic cancer cases. The results of the leukemia case/control analysis show no association with the radiation exposure variables: occupational radiation exposure; uranium mining exposure; having ever lived in a type A home (uranium tailings home); and radiation therapy. The lung cancer case/control analysis shows a significant association with only the radiation exposure variable, uranium mining history, indicating cases were more likely to have been uranium miners than were controls. As with leukemia, the study found no association between lung cancer and living in a uranium mill tailings home. The relatively low radiation exposures typical of type A homes and the small number of persons exposed make it very difficult to establish, by epidemiologic methods, that a risk exists

  3. Bladder Exstrophy: An Epidemiologic Study From the International Clearinghouse for Birth Defects Surveillance and Research, and an Overview of the Literature

    Science.gov (United States)

    SIFFEL, CSABA; CORREA, ADOLFO; AMAR, EMMANUELLE; BAKKER, MARIAN K.; BERMEJO-SÁNCHEZ, EVA; BIANCA, SEBASTIANO; CASTILLA, EDUARDO E.; CLEMENTI, MAURIZIO; COCCHI, GUIDO; CSÁKY-SZUNYOGH, MELINDA; FELDKAMP, MARCIA L.; LANDAU, DANIELLE; LEONCINI, EMANUELE; LI, ZHU; LOWRY, R. BRIAN; MARENGO, LISA K.; MASTROIACOVO, PIERPAOLO; MORGAN, MARGERY; MUTCHINICK, OSVALDO M.; PIERINI, ANNA; RISSMANN, ANKE; RITVANEN, ANNUKKA; SCARANO, GIOACCHINO; SZABOVA, ELENA; OLNEY, RICHARD S.

    2015-01-01

    Bladder exstrophy (BE) is a complex congenital anomaly characterized by a defect in the closure of the lower abdominal wall and bladder. We aimed to provide an overview of the literature and conduct an epidemiologic study to describe the prevalence, and maternal and case characteristics of BE. We used data from 22 participating member programs of the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR). All cases were reviewed and classified as isolated, syndrome, and multiple congenital anomalies. We estimated the total prevalence of BE and calculated the frequency and odds ratios for various maternal and case characteristics. A total of 546 cases with BE were identified among 26,355,094 births. The total prevalence of BE was 2.07 per 100,000 births (95% CI: 1.90–2.25) and varied between 0.52 and 4.63 among surveillance programs participating in the study. BE was nearly twice as common among male as among female cases. The proportion of isolated cases was 71%. Prevalence appeared to increase with increasing categories of maternal age, particularly among isolated cases. The total prevalence of BE showed some variations by geographical region, which is most likely attributable to differences in registration of cases. The higher total prevalence among male cases and older mothers, especially among isolated cases, warrants further attention. PMID:22002949

  4. Kaposi sarcoma incidence in Mozambique: national and regional estimates.

    Science.gov (United States)

    Meireles, Paula; Albuquerque, Gabriela; Vieira, Mariana; Foia, Severiano; Ferro, Josefo; Carrilho, Carla; Lunet, Nuno

    2015-11-01

    Kaposi sarcoma is expressed in four clinical variants, all associated with human herpes virus type 8 infection, namely, classic, endemic, immunosuppression-related and AIDS-related. The latter currently accounts for most of the burden of Kaposi sarcoma in sub-Saharan Africa, reflecting the frequency of HIV infection and its management. We aimed to estimate the incidence of Kaposi sarcoma in Mozambique and in its provinces. We estimated the number of incident cases of Kaposi sarcoma by adding up the expected number of endemic and AIDS-related cases. The former were estimated from the rates observed in Kyandondo, Uganda (1960-1971). The latter were computed from the number of AIDS-related deaths in each region, assuming that the ratio between the AIDS-related Kaposi sarcoma incident cases and the number of AIDS-related deaths observed in the city of Beira applies to all regions. A total of 3862 Kaposi sarcoma cases were estimated to have occurred in Mozambique in 2007, mostly AIDS-related, in the age group 25-49 years, and in provinces from South/Centre. The age-standardized incidence rates were 36.1/100 000 in men and 11.5/100 000 in women, with a more than three-fold variation across provinces. We estimated a high incidence of Kaposi sarcoma in Mozambique, along with large regional differences. These results can be used to improve disease management and to sustain political decisions on health policies.

  5. Did the 'Great Recession' produce a depression in tuberculosis incidence?

    Science.gov (United States)

    Holland, D P; Person, A K; Stout, J E

    2011-05-01

    In 2009, the United States experienced a record drop in its tuberculosis (TB) case rate, coinciding with a major economic downturn. To investigate this relationship, we modeled short-term changes in gross domestic product, unemployment, and immigration as predictors of TB incidence. We also correlated each state's 2009-2010 change in unemployment with its 2008-2009 change in TB incidence. Although economic factors did not explain the decline, the 2009-2010 change in unemployment negatively correlated with incidence. We hypothesize that factors related to increased unemployment, such as diagnostic delay, may have played a role in the sudden drop in TB case rates. PMID:21756525

  6. Changing patterns of Hodgkin lymphoma incidence in Singapore

    DEFF Research Database (Denmark)

    Hjalgrim, H.; Seow, A.; Rostgaard, K.;

    2008-01-01

    rates increased annually by 7.0% (95% confidence interval 3.4%-10.7%) and 3.4% (0.1%-6.8%), respectively, in men and by 13.7% (9.1%-18.6%) and 12.2% (7.8-16.8%), respectively, in women between 1968 and 2004. However, the incidence peak remained considerably lower than what can be observed in young......A bimodal age-specific incidence pattern with a relatively high proportion of cases occurring in adolescents and young adults is a hallmark of Hodgkin lymphoma (HL) epidemiology in Western industrialized countries. The young adult incidence peak is believed to reflect the association between HL...

  7. Nasopharyngeal carcinoma incidence and mortality in China in 2010

    Institute of Scientific and Technical Information of China (English)

    Kuang-Rong Wei; Rong-Shou Zheng; Si-Wei Zhang; Zhi-Heng Liang; Zhi-Xiong Ou; Wan-Qing Chen

    2014-01-01

    Nasopharyngeal carcinoma (NPC) is common in South China. Although regional epidemiological data on NPC in China is available, national epidemiological data have been unavailable up to now. The goal of this study was to analyze the NPC incidence and mortality data in some domestic cancer registries, estimate these rates in China in 2010, and provide scientific information that can be harnessed for NPC control and prevention. To accomplish this goal, NPC incidence and mortality data for 2010 were col ected from 145 Chinese cancer registries from which data were included in the 2013 National Cancer Registry Annual Report. Such indices as its incident and death numbers, crude rates, age-standardized rates and truncated rates were calculated and analyzed. The incidence and mortality in China and constituent areas were estimated according to the national population in 2010. An estimated 41,503 new cases and 20,058 deaths were attributed to NPC in China in 2010, accounting for 1.34%of al new cancer cases and 1.03% of all cancer-related deaths that year in China. Crude incidence and mortality were 3.16/100,000 and 1.53/100,000, respectively. World age-standardized incidence and mortality were 2.44/100,000 and 1.18/100,000, respectively. Incidence and mortality were higher among males than among females and slightly higher in urban areas than in rural areas. Among seven Chinese administrative regions, NPC incidence and mortality were obviously higher in South China than in other regions and lowest in North China. The male and female age-specific incidence and mortality both rose quickly from age 25-29 years, but peaked at different ages and varied by location. These results demonstrated that NPC incidence and mortality in China especially in South China were at high levels in the world, and suggested that control and prevention efforts should be enhanced.

  8. Colonoscopic perforation:Incidence,risk factors,management and outcome

    Institute of Scientific and Technical Information of China (English)

    Varut; Lohsiriwat

    2010-01-01

    This review discusses the incidence,risk factors,management and outcome of colonoscopic perforation(CP).The incidence of CP ranges from 0.016% to 0.2% following diagnostic colonoscopies and could be up to 5% following some colonoscopic interventions.The perforations are frequently related to therapeutic colonoscopies and are associated with patients of advanced age or with multiple comorbidities.Management of CP is mainly based on patients' clinical grounds and their underlying colorectal diseases.Current t...

  9. The Initial Incidence of a Carbon Tax across US States

    OpenAIRE

    Roberton C. Williams III; Gordon, Hal; Burtraw, Dallas; Carbone, Jared C.; Richard D. Morgenstern

    2014-01-01

    Carbon taxes introduce potentially uneven cost burdens across the population. The distribution of these costs is especially important in affecting political outcomes. This paper links dynamic overlapping-generations and microsimulation models of the United States to estimate the initial incidence of a carbon tax across states. Geographic differences in incidence are driven primarily by differences in sources of income. Differing patterns of energy use also matter but are relatively less impor...

  10. Meteorological effects on the incidence of pneumococcal bacteremia in Denmark

    DEFF Research Database (Denmark)

    Tvedebrink, Torben; Lundbye-Christensen, Søren; Thomsen, Reimar W.;

    The seasonal nature of invasive pneumococcal disease with peak incidences during winter months is well recognized (Dowell 2003, Talbot 2005, Watson 2006). However few detailed studies of the temporal relationship between actual climatic changes and subsequent pneumococcal disease are available. We...... perform an 8-year longitudinal population-based ecological study in a Danish county to examine whether foregoing changes in meteorological parameters, including temperature, relative humidity, precipitation, and wind velocity, predicted variations in pneumococcal bacteremia (PB) incidence....

  11. Good Gradings of Generalized Incidence Rings

    CERN Document Server

    Price, Kenneth L

    2011-01-01

    This inquiry is based on both the construction of generalized incidence rings due to Gene Abrams and the construction of good group gradings of incidence algebras due to Molli Jones. We provide conditions for a generalized incidence ring to be graded isomorphic to a subring of an incidence ring over a preorder. We also extend Jones's construction to good group gradings for incidence algebras over preorders with crosscuts of length one or two.

  12. Dissociative Tendencies and Traffic Incidents

    Directory of Open Access Journals (Sweden)

    Valle, Virginia

    2012-01-01

    Full Text Available This paper analyses the relationship between dissociative experiences and road traffic incidents (crashes and traffic tickets in drivers (n=295 from Mar del Plata (Argentina city. A self-report questionnaire was applied to assess traffic crash involvement and sociodemographic variables. Dissociative tendencies were assessed by a modified version of the DES scale. To examine differences in DES scores tests of the difference of means were applied. Drivers who reported to be previously involved in traffic incidents obtained higher puntuations in the dissociative experiences scale than drivers who did not report such events. This result is observed for the total scale and for the three sub-scales (absorption, amnesia and depersonalization. However, differences appeared mainly for minor damage collisions. Further studies are needed to evaluate the role of dissociative tendencies as a risk factor in road traffic safety.

  13. 中国儿童与老年健康证据转化平台的构建与应用%The establishment and application of Chinese Clearinghouse for Evidence Translation in Child & Aging Health

    Institute of Scientific and Technical Information of China (English)

    拜争刚; 刘少堃; 常健博; 赵坤; 李惠菊; Iris CHI; Haluk SOYDAN; 杨克虎

    2015-01-01

    Objective To describe the development of the Chinese Clearinghouse for Evi-dence Translation in Child&Aging Health ( CCET) and its aims and working methods .Methods Child welfare and aging health advisory committees were established .Using a scientific assessment tool, committee members appraised and selected related interventions from home and abroad and they were translated by our team .Working with Lanzhou Boyang Software Engineering Inc ., the structure and interface of CCET website were planed and designed based on its content and intended function.Feasible interventions and other information ( e.g.basic information of diseases , assessment scale, reporting standards etc .) were uploaded and displayed on the website to establish CCET and were disseminated through media like WeChat .Results CCET currently consists of six modules:child health , elderly health , assessment scale , reporting standards , dissemination and implementa-tion methods , and the Evidence-based Database for Aging Depression .Child and elderly health pro-grams listed in the CCET have high quality and adaptability .They were selected and appraised by experts from China and the United States using scientific assessment scales .And now, some relative research institutions and communities intent to join CCET′s research and implement translated pro-gram.Conclusion CCET devotes to evidence-based method training , establishing the appraising system for the scientificity and adaptability of health intervention , program training , service agency capability promotion and developing comprehensive intervention programs .With sufficient informa-tion and a user-friendly homepage , CCET provides support to improve evidence-informed decision making in child and elderly care .%目的:介绍并推广中国儿童与老年健康证据转化平台( Chinese Clearinghouse for Evidence Trans-lation in Child&Aging Health,CCET)。方法分别成立儿童、老年健康顾问委员会,利用科学的

  14. Incidence of respiratory distress syndrome

    International Nuclear Information System (INIS)

    Objective: To determine the incidence of respiratory distress syndrome (RDS) in hospital born babies. Subjects and Methods: All live born infants delivered at the hospital and who fulfilled the diagnostic criteria of respiratory distress syndrome (RDS) were included in the study. Results: Ninety-four neonates developed RDS. Out of these, 88 (93.61%) were preterm and 06 (6.38%) were term infants. There was a male preponderance (65.95%). RDS was documented in 1.72% of total live births. 37.28% of preterm and 0.11% of term neonates born at the hospital. The incidence of RDS was 100% at 26 or less weeks of gestation, 57.14% at 32 weeks, and 3.70% at 36 weeks. The mortality with RDS was 41 (43.61%). Conclusion: RDS is the commonest cause of respiratory distress in the newborn, particularly, in preterm infants. It carries a high mortality rate and the incidence is more than that documented in the Western world. (author)

  15. Investigation and Analysis of The Incidence and Related Factors of Dental Caries In 12 Years Old Children in Panzhihua Region%攀枝花地区12岁儿童龋病的发病率及相关因素调查分析

    Institute of Scientific and Technical Information of China (English)

    胡勇

    2014-01-01

    Objective:To investigate the incidence and related factors of caries on 12-year-old children in Panzhihua region.Methods:By random sampling method, oral examination and survey were done to understand the incidence of dental caries and oral hygiene in Panzhihua region for 342 children aged 12.Results:Caries incidence was higher in urban than that in rural areas (P<0.05). Caries rate of women was higher than men, and the difference was statistically significant (P<0.05). In the factors related to children's oral health behavior, brushing 2 or 3 times per day the caries incidence of was 52.7%and brushing 0 or 1 time per day the incidence of was 32.9%, the difference was statistically significant (P<0.01). Caries incidence of children commonly using fluoride toothpaste was significantly lower than that of children infrequently using fluoride toothpaste (P<0.05). Caries incidence of children with regular dental check was significantly lower than that that of children with rarely or never performed oral examination (P<0.01). Survey showed most children were lack of knowledge of oral health. Only 12.4%(42/339) of children considered it's beneficial to use fluoride toothpaste for preventing caries.Conclusion:Frequency of tooth brushing, application of fluoride toothpaste and oral examination were important factors affecting caries. Medical and health institutions should strengthen the children's oral health education work to further improve young children's oral health awareness.%目的::调查攀枝花地区12岁儿童龋病的发病率及相关因素。方法:按随机抽样的方法,对攀枝花地区342名12岁儿童进行口腔检查和问卷调查,了解龋病发生率和口腔卫生情况。结果:儿童患龋率城市高于农村(P<0.05),女性患龋率均高于男性,差异具有统计学意义(P<0.05)。儿童口腔健康行为的相关因素中,日刷牙次数(2~3)次与(0~1)次两组儿童患龋率分别为52.7%和32.9%,差异具有统计

  16. The Tricastin incident; L'incident du Tricastin

    Energy Technology Data Exchange (ETDEWEB)

    Nifenecker, H.

    2008-07-01

    The author comments the incident which occurred on the Tricastin site in July 2008: the release of 30 cubic meters of a uranium-containing solution. First, he recalls the international nuclear event scale, outlines that the Tricastin is not a nuclear power plant, that uranium is more a chemical toxic product than a radiological toxic product. After having briefly recalled some dose threshold values, he discusses the presence of uranium in the environment, and states that the event is actually a non-event which has been in fact magnified by the media

  17. Swedish hunters' safety behaviour and experience of firearm incidents.

    Science.gov (United States)

    Junuzovic, Mensura; Midlöv, Patrik; Lönn, Sara Larsson; Eriksson, Anders

    2013-11-01

    Since any firearm injury is potentially lethal, it is of great interest to prevent firearm incidents. This study investigated such incidents during hunting and Swedish hunters' safety behaviour. A 48-item questionnaire was posted to a random sample of 1000 members of the Swedish Association for Hunting and Wildlife Management. The questions considered demographics, hunting experience/hunting habits/safety behaviour/attitudes and experience of careless weapon handling, hunters' weapons and safety behaviour relating to weapons, health status, firearm incidents and their preventability, and personal comments on the questionnaire. The response rate was almost 50%. The mean age of the responders was 54 years; 5% were females. Almost none (1%) reported hunting under the influence of alcohol. Young age and male sex were positively associated with risk behaviour, although the presence of multiple risk behaviours in the same responder was not common. A very high degree of compliance with Swedish laws regarding weapon storage was reported. One-quarter of the responders had witnessed a firearm incident caused by another hunter, which in most situations did not result in human injury or death. An unsafetied weapon was the most common reported "cause" of these incidents. Experience of a firearm incident was not uncommon and the majority of the responders considered the incident in question to be preventable. This study provides a picture of the possible risk behaviour among hunters and the results suggest that future prevention work should target safer weapon handling.

  18. The Epidemiology of Incident Fracture from Cradle to Senescence.

    Science.gov (United States)

    Pasco, Julie A; Lane, Stephen E; Brennan-Olsen, Sharon L; Holloway, Kara L; Timney, Elizabeth N; Bucki-Smith, Gosia; Morse, Amelia G; Dobbins, Amelia G; Williams, Lana J; Hyde, Natalie K; Kotowicz, Mark A

    2015-12-01

    To reduce the burden of fracture, not only does bone fragility need to be addressed, but also injury prevention. Thus, fracture epidemiology irrespective of degree of trauma is informative. We aimed to determine age-and-sex-specific fracture incidence rates for the Barwon Statistical Division, Australia, 2006-2007. Using radiology reports, incident fractures were identified for 5342 males and 4512 females, with incidence of 210.4 (95 % CI 204.8, 216.2) and 160.0 (155.3, 164.7)/10,000/year, respectively. In females, spine (clinical vertebral), hip (proximal femoral) and distal forearm fractures demonstrated a pattern of stable incidence through early adult life, with an exponential increase beginning in postmenopausal years for fractures of the forearm followed by spine and hip. A similar pattern was observed for the pelvis, humerus, femur and patella. Distal forearm, humerus, other forearm and ankle fractures showed incidence peaks during childhood and adolescence. For males, age-related changes mimicked the female pattern for fractures of the spine, hip, ribs, pelvis and humerus. Incidence at these sites was generally lower for males, particularly among the elderly. A similar childhood-adolescent peak was seen for the distal forearm and humerus. For ankle fractures, there was an increase during childhood and adolescence but this extended into early adult life; in contrast to females, there were no further age-related increases. An adolescent-young adult peak incidence was observed for fractures of the face, clavicle, carpal bones, hand, fingers, foot and toe, without further age-related increases. Examining patterns of fracture provides the evidence base for monitoring temporal changes in fracture burden, and for identifying high-incidence groups to which fracture prevention strategies could be directed. PMID:26319674

  19. Stochastic modeling of the dynamics of incident-induced lane traffic states for incident-responsive local ramp control

    Science.gov (United States)

    Sheu, Jiuh-Biing

    2007-12-01

    Incident-induced traffic congestion has been recognized as a critical issue to solve in the development of advanced freeway incident management systems. This paper investigates the applicability of a stochastic optimal control approach to real-time incident-responsive local ramp control on freeways. The architecture of the proposed ramp control system embeds two primary functions including (1) real-time estimation of incident-induced lane traffic states and (2) dynamic prediction of ramp-metering rates in response to the changes of incident impacts. To accomplish the above two goals, a discrete-time nonlinear stochastic optimal control model is proposed, followed by the development of a recursive prediction algorithm. Based on the simulation data, the numerical results of model tests indicate that the proposed method permits relieving incident impacts particularly under low-volume and medium-volume conditions, relative to high-volume lane-blocking conditions. Particularly, the incident-induced queue lengths can be improved by 50.1% and 67.9%, compared to the existing ramp control and control-free strategies, respectively.

  20. The Porto Alegre paradox: social determinants and tuberculosis incidence

    Directory of Open Access Journals (Sweden)

    Lisiane Morelia Weide Acosta

    2014-01-01

    Full Text Available INTRODUCTION: The incidence of tuberculosis (TB is strongly associated with social and economic factors. The city of Porto Alegre, in the South of Brazil, has one of the highest Human Development Index and Gross Domestic Product per capita of the country. One would expect that the incidence of tuberculosis in such a place were low. However, the city has very high rates of incidence, the highest among Brazilian capitals. This paradox prompted this work, whose objectives were to analyze the spatial distribution of the incidence rate of bacilliferous pulmonary tuberculosis throughout the neighborhoods of Porto Alegre and its association with socioeconomic indicators. METHODS: Ecological non-concurrent cohort study. The units of analysis were the neighborhoods of the city. The average annual incidence of bacilliferous pulmonary tuberculosis for the period 2000 to 2005 and seven socioeconomic variables were analyzed, with information obtained from the IBGE and the Mortality Information System. Spatial techniques and multivariate analyzes were used to check associations. Inequalities were also measured. RESULTS: The spatial distribution of the incidence rate of bacilliferous pulmonary tuberculosis is very similar, i.e., associated with the distribution of socioeconomic factors. The Relative Index of Inequality was 7.9, showing the great difference in the incidence rate between neighborhoods. CONCLUSION: Porto Alegre presents high incidence rates of bacilliferous pulmonary tuberculosis, which distribution through the neighborhoods of the city is associated with socioeconomic factors. The city's high rate is due to the extremely high incidence rates in its poorest neighborhoods. The authors raise hypotheses and suggest interventions.

  1. Brief Report: Incidence of Ophthalmologic Disorders in Children with Autism

    Science.gov (United States)

    Ikeda, Jamie; Davitt, Bradley V.; Ultmann, Monica; Maxim, Rolanda; Cruz, Oscar A.

    2013-01-01

    Purpose: To determine the incidence of ophthalmologic disorders in children with autism and related disorders. Design: Retrospective chart review. Four hundred and seven children diagnosed with autism or a related disorder between 1998 and 2006. One hundred and fifty-four of these children completed a comprehensive ophthalmology exam by a…

  2. Critical Incident Reporting in Anaesthesia: A Prospective Internal Audit

    Directory of Open Access Journals (Sweden)

    Sunanda Gupta

    2009-01-01

    Full Text Available Critical incident monitoring is useful in detecting new problems, identifying near misses′ and analyzing factors or events leading to mishaps, which can be instructive for trainees. This study was aimed at investigating potential risk factors and analyze events leading to pen-operative critical incidents in order to develop a critical incident reporting system. W conducted a one year prospective analysis of voluntarily reported 24- hour-perioperative critical inci-dents, occurring in patients subjected to anaesthesia. During a one year period from December 2006 to December 2007, 14,134 anaesthetics were administered and 112(0.79% critical incidents were reported with complete recov-ery in 71.42%(n=80 and mortality in 28.57% (n=32 cases. Incidents occurred maximally in 0-10 years age (23.21%, ASA 1(61.61%, in general surgery patients (43.75%, undergoing emergency surgery (52.46% and during day time (75.89%. Incidence was more in the operating theatre (77.68%, during maintenance (32.04% and post-operative phase (25.89% and in patients who received general anaesthesia (75.89%. Critical incidents occurred clue to fac-tors related to anaesthesia (42.85%, patient (37.50% and surgery (16.96°lo. Among anaesthesia related critical incidents (42.85% n=48/112, respiratory events were maximum (66.66% mainly at induction (37.5% and emer-gence (43.75%, and factors responsible were human error (85.41%, pharmacological factors (10.41% and equip-ment error (4.17%. Incidence of mortality was 22.6 per10, 000 anaesthetics (32/14,314, mostly attributable to risk factors in patient (59.38% as compared to anaesthesia (25% and surgery (9.38%. There were 8 anaesthesia related deaths (5.6 per 10, 000 anaesthetics where human error (75% attributed to lack of judgment (67.50% was an important causative factor. We conclude that critical incident reporting system may be a valuable part of quality assurance to develop policies to prevent recurrence and enhance patient

  3. Grazing incidence diffraction : A review

    Energy Technology Data Exchange (ETDEWEB)

    Gilles, B. [LTPCM, ENSEEG. St. Martin d`Heres. (France)

    1996-09-01

    Different Grazing Incidence Diffraction (GID) methods for the analysis of thin films and multilayer structures are reviewed in three sections: the reflectivity is developed in the first one, which includes the non-specular diffuse scattering. The second one is devoted to the extremely asymmetric Bragg diffraction and the third one to the in-plane Bragg diffraction. Analytical formulations of the scattered intensities are developed for each geometry, in the framework of the kinetical analysis as well as the dynamical theory. Experimental examples are given to illustrate the quantitative possibility of the GID techniques.

  4. Amelia: A Multi-Center Descriptive Epidemiologic Study in a Large Dataset from the International Clearinghouse for Birth Defects Surveillance and Research, and Overview of the Literature

    Science.gov (United States)

    BERMEJO-SÁNCHEZ, EVA; CUEVAS, LOURDES; AMAR, EMMANUELLE; BAKKER, MARIAN K.; BIANCA, SEBASTIANO; BIANCHI, FABRIZIO; CANFIELD, MARK A.; CASTILLA, EDUARDO E.; CLEMENTI, MAURIZIO; COCCHI, GUIDO; FELDKAMP, MARCIA L.; LANDAU, DANIELLE; LEONCINI, EMANUELE; LI, ZHU; LOWRY, R. BRIAN; MASTROIACOVO, PIERPAOLO; MUTCHINICK, OSVALDO M.; RISSMANN, ANKE; RITVANEN, ANNUKKA; SCARANO, GIOACCHINO; SIFFEL, CSABA; SZABOVA, ELENA; MARTÍNEZ-FRÍAS, MARÍA-LUISA

    2015-01-01

    This study describes the epidemiology of congenital amelia (absence of limb/s), using the largest series of cases known to date. Data were gathered by 20 surveillance programs on congenital anomalies, all International Clearinghouse for Birth Defects Surveillance and Research members, from all continents but Africa, from 1968 to 2006, depending on the program. Reported clinical information on cases was thoroughly reviewed to identify those strictly meeting the definition of amelia. Those with amniotic bands or limb-body wall complex were excluded. The primary epidemiological analyses focused on isolated cases and those with multiple congenital anomalies (MCA). A total of 326 amelia cases were ascertained among 23,110,591 live births, stillbirths and (for some programs) elective terminations of pregnancy for fetal anomalies. The overall total prevalence was 1.41 per 100,000 (95% confidence interval: 1.26–1.57). Only China Beijing and Mexico RYVEMCE had total prevalences, which were significantly higher than this overall total prevalence. Some under-registration could influence the total prevalence in some programs. Liveborn cases represented 54.6% of total. Among monomelic cases (representing 65.2% of nonsyndromic amelia cases), both sides were equally involved, and the upper limbs (53.9%) were slightly more frequently affected. One of the most interesting findings was a higher prevalence of amelia among offspring of mothers younger than 20 years. Sixty-nine percent of the cases had MCA or syndromes. The most frequent defects associated with amelia were other types of musculoskeletal defects, intestinal, some renal and genital defects, oral clefts, defects of cardiac septa, and anencephaly. PMID:22002956

  5. Sirenomelia: An Epidemiologic Study in a Large Dataset From the International Clearinghouse of Birth Defects Surveillance and Research, and Literature Review

    Science.gov (United States)

    ORIOLI, IÊDA M.; AMAR, EMMANUELLE; ARTEAGA-VAZQUEZ, JAZMIN; BAKKER, MARIAN K.; BIANCA, SEBASTIANO; BOTTO, LORENZO D.; CLEMENTI, MAURIZIO; CORREA, ADOLFO; CSAKY-SZUNYOGH, MELINDA; LEONCINI, EMANUELE; LI, ZHU; LÓPEZ-CAMELO, JORGE S.; LOWRY, R. BRIAN; MARENGO, LISA; MARTÍNEZ-FRÍAS, MARÍA-LUISA; MASTROIACOVO, PIERPAOLO; MORGAN, MARGERY; PIERINI, ANNA; RITVANEN, ANNUKKA; SCARANO, GIOACCHINO; SZABOVA, ELENA; CASTILLA, EDUARDO E.

    2015-01-01

    Sirenomelia is a very rare limb anomaly in which the normally paired lower limbs are replaced by a single midline limb. This study describes the prevalence, associated malformations, and maternal characteristics among cases with sirenomelia. Data originated from 19 birth defect surveillance system members of the International Clearinghouse for Birth Defects Surveillance and Research, and were reported according to a single pre-established protocol. Cases were clinically evaluated locally and reviewed centrally. A total of 249 cases with sirenomelia were identified among 25,290,172 births, for a prevalence of 0.98 per 100,000, with higher prevalence in the Mexican registry. An increase of sirenomelia prevalence with maternal age less than 20 years was statistically significant. The proportion of twinning was 9%, higher than the 1% expected. Sex was ambiguous in 47% of cases, and no different from expectation in the rest. The proportion of cases born alive, premature, and weighting less than 2,500 g were 47%, 71.2%, and 88.2%, respectively. Half of the cases with sirenomelia also presented with genital, large bowel, and urinary defects. About 10–15% of the cases had lower spinal column defects, single or anomalous umbilical artery, upper limb, cardiac, and central nervous system defects. There was a greater than expected association of sirenomelia with other very rare defects such as bladder exstrophy, cyclopia/holoprosencephaly, and acardia-acephalus. The application of the new biological network analysis approach, including molecular results, to these associated very rare diseases is suggested for future studies. PMID:22002878

  6. Phocomelia: A Worldwide Descriptive Epidemiologic Study in a Large Series of Cases From the International Clearinghouse for Birth Defects Surveillance and Research, and Overview of the Literature

    Science.gov (United States)

    Bermejo-Sánchez, Eva; Cuevas, Lourdes; Amar, Emmanuelle; Bianca, Sebastiano; Bianchi, Fabrizio; Botto, Lorenzo D.; Canfield, Mark A.; Castilla, Eduardo E.; Clementi, Maurizio; Cocchi, Guido; Landau, Danielle; Leoncini, Emanuele; Li, Zhu; Lowry, R. Brian; Mastroiacovo, Pierpaolo; Mutchinick, Osvaldo M.; Rissmann, Anke; Ritvanen, Annukka; Scarano, Gioacchino; Siffel, Csaba; Szabova, Elena; Martínez-Frías, María-Luisa

    2015-01-01

    Epidemiologic data on phocomelia are scarce. This study presents an epidemiologic analysis of the largest series of phocomelia cases known to date. Data were provided by 19 birth defect surveillance programs, all members of the International Clearinghouse for Birth Defects Surveillance and Research. Depending on the program, data corresponded to a period from 1968 through 2006. A total of 22,740,933 live births, stillbirths and, for some programs, elective terminations of pregnancy for fetal anomaly (ETOPFA) were monitored. After a detailed review of clinical data, only true phocomelia cases were included. Descriptive data are presented and additional analyses compared isolated cases with those with multiple congenital anomalies (MCA), excluding syndromes. We also briefly compared congenital anomalies associated with nonsyndromic phocomelia with those presented with amelia, another rare severe congenital limb defect. A total of 141 phocomelia cases registered gave an overall total prevalence of 0.62 per 100,000 births (95% confidence interval: 0.52–0.73). Three programs (Australia Victoria, South America ECLAMC, Italy North East) had significantly different prevalence estimates. Most cases (53.2%) had isolated phocomelia, while 9.9% had syndromes. Most nonsyndromic cases were monomelic (55.9%), with an excess of left (64.9%) and upper limb (64.9%) involvement. Most nonsyndromic cases (66.9%) were live births; most isolated cases (57.9%) weighed more than 2,499 g; most MCA (60.7%) weighed less than 2,500 g, and were more likely stillbirths (30.8%) or ETOPFA (15.4%) than isolated cases. The most common associated defects were musculoskeletal, cardiac, and intestinal. Epidemiological differences between phocomelia and amelia highlighted possible differences in their causes. PMID:22002800

  7. 武汉市部分中小学生近视患病率及其相关因素分析%Analysis the incidence of myopia and its related factors in students in Wuchang distrct

    Institute of Scientific and Technical Information of China (English)

    戴鸿斌; 蔡春艳; 欧阳芳; 覃银燕; 黄华林; 许菲

    2015-01-01

    目的:分析武汉市武昌区部分中小学生视力状况,了解各年龄段学生的近视患病率及其相关影响因素,为预防及治疗近视提供依据。方法筛查武汉市武昌区部分中小学生视力,分析近视患病率,通过问卷调查分析近视发病相关因素。结果调查总人数为3587人,近视患病率为34.12%。随着年龄的增长,近视患病率呈上升趋势。女生近视患病率36.75%较男生31.87%高,<0.05。近视的发生与室内用眼时间长,室外活动时间短相关,<0.05。结论中小学生近视患病与长时间看书、写作业、看电视及上网等均有关。%Objective To study the prevalence of myopia among primary and secondary school students in Wuchang district in Wuhan and to explore the influence factors of myopia and to provide bases to prevent myopia. Methods Study the prevalence of myopia among primary and secondary students,and investigate the influence fac-tors of myopia by questionnaires. Results There were 3587 students were surveyed, the prevalence rate of myopia was 34.12%. The prevalence rate of myopia was increasing with grades. The prevalence rate of myopia was higher among girls than boys. Myopia was related with long time in room and less time outdoor. Conclusion Myopia was related with long time reading,writing,watching TV and computer and so on.

  8. Increasing incidence of diabetes after gestational diabetes

    DEFF Research Database (Denmark)

    Lauenborg, Jeannet; Hansen, Torben; Jensen, Dorte Møller;

    2004-01-01

    To study the incidence of diabetes among women with previous diet-treated gestational diabetes mellitus (GDM) in the light of the general increasing incidence of overweight and diabetes and to identify risk factors for the development of diabetes....

  9. USFA NFIRS 2013 Fire Incident & Cause Data

    Data.gov (United States)

    Department of Homeland Security — The 2013 Fire Causes & Incident data was provided by the U.S. Fire Administration’s (USFA) National Fire Data Center’s (NFDC’s) National Fire Incident Reporting...

  10. Ionospheric Oblique Incidence Soundings by Satellites

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The oblique incidence sweep-frequency ionospheric sounding technique uses the same principle of operation as the vertical incidence sounder. The primary difference...

  11. Estimated HIV incidence in the United States, 2006-2009.

    Directory of Open Access Journals (Sweden)

    Joseph Prejean

    Full Text Available BACKGROUND: The estimated number of new HIV infections in the United States reflects the leading edge of the epidemic. Previously, CDC estimated HIV incidence in the United States in 2006 as 56,300 (95% CI: 48,200-64,500. We updated the 2006 estimate and calculated incidence for 2007-2009 using improved methodology. METHODOLOGY: We estimated incidence using incidence surveillance data from 16 states and 2 cities and a modification of our previously described stratified extrapolation method based on a sample survey approach with multiple imputation, stratification, and extrapolation to account for missing data and heterogeneity of HIV testing behavior among population groups. PRINCIPAL FINDINGS: Estimated HIV incidence among persons aged 13 years and older was 48,600 (95% CI: 42,400-54,700 in 2006, 56,000 (95% CI: 49,100-62,900 in 2007, 47,800 (95% CI: 41,800-53,800 in 2008 and 48,100 (95% CI: 42,200-54,000 in 2009. From 2006 to 2009 incidence did not change significantly overall or among specific race/ethnicity or risk groups. However, there was a 21% (95% CI:1.9%-39.8%; p = 0.017 increase in incidence for people aged 13-29 years, driven by a 34% (95% CI: 8.4%-60.4% increase in young men who have sex with men (MSM. There was a 48% increase among young black/African American MSM (12.3%-83.0%; p<0.001. Among people aged 13-29, only MSM experienced significant increases in incidence, and among 13-29 year-old MSM, incidence increased significantly among young, black/African American MSM. In 2009, MSM accounted for 61% of new infections, heterosexual contact 27%, injection drug use (IDU 9%, and MSM/IDU 3%. CONCLUSIONS/SIGNIFICANCE: Overall, HIV incidence in the United States was relatively stable 2006-2009; however, among young MSM, particularly black/African American MSM, incidence increased. HIV continues to be a major public health burden, disproportionately affecting several populations in the United States, especially MSM and racial and

  12. [Ecological study of Pyroglyphides mites in house dust in the Grenoble area. A qualitative approach and incidence of various parameters: seasons, altitude, temperature and relative dampness in their multiplication].

    Science.gov (United States)

    Lascaud, D

    1978-01-01

    This study concerns the analysis of 70 samples of dust mites taken periodically from 13 sample areas or mattresses at different altitudes. It shows the presence of Pyroglyphid mites in all the mattresses studied. Four species were found: Dermatophagoides pteronyssinus, Dermatophagoides farinae, Euroglyphus maynei and Dermatophagoides evansi. From a quantitative point of view, the statistical analysis of the results obtained allows the following conclusions to be drawn: -- All the Pyroglyphids (adults and young) undergo seasonal fluctuations at low, middle and high altitude. In the plains and at middle altitude these mites have a seasonal maximum and minimum. At high altitude only the seasonal maximum can be determined. -- The number of Pyroglyphids found is much higher in the plaine than at middle altitude and at middle altitude than at high altitude. The influence of altitude can be demonstrated with certitude. -- The conditions of temperature and relative dampness most favourable to the multiplication of mites are found in the plaine. At middle and high altitude these conditions are only met in summer. In flat country the statistical analysis allows us to show the existance of a correlation between the rate of dampness and the number of Pyroglyphids, and more specially, between the dampness rate and Dermatophagoides farinae, a predominant species at this sampling area. At middle and high altitude such a correlation cannot be shown clearly. At the three altitudes considered, no correlation can be established between the temperature and the number of Pyroglyphid mites found.

  13. Increasing incidence of diabetes after gestational diabetes

    DEFF Research Database (Denmark)

    Lauenborg, Jeannet; Hansen, Torben; Jensen, Dorte Møller;

    2004-01-01

    To study the incidence of diabetes among women with previous diet-treated gestational diabetes mellitus (GDM) in the light of the general increasing incidence of overweight and diabetes and to identify risk factors for the development of diabetes.......To study the incidence of diabetes among women with previous diet-treated gestational diabetes mellitus (GDM) in the light of the general increasing incidence of overweight and diabetes and to identify risk factors for the development of diabetes....

  14. Detecting Terrorism Incidence Type from News Summary

    DEFF Research Database (Denmark)

    Nizamani, Sarwat; Memon, Nasrullah

    2012-01-01

    The paper presents the experiments to detect terrorism incidence type from news summary data. We have applied classification techniques on news summary data to analyze the incidence and detect the type of incidence. A number of experiments are conducted using various classification algorithms...

  15. 重症监护病房呼吸机相关肺炎的发病率及相关病原菌调查%Investigation on incidence and related pathogenic bacteria of ventilatorassociated pneumonia in ICU

    Institute of Scientific and Technical Information of China (English)

    刘向欣; 尹素凤

    2012-01-01

    OBJECTIVE To improve the treatment level of ureteral transitional cell carcinoma- METHODS From July 2001 to October 2010, patients with ureteral transitional cell carcinoma were diagnosed by ureteroscopy, biopsy examination. RESULTS 15 cases were confirmed as transitional cell carcinoma by pathological examination. Including 3 cases of grade Ⅰ , 10 cases of grade Ⅱ , 2 cases of grade Ⅲ. TNM classification, 4 cases of T2, 11 cases of T3, 1 case of T+ 16 patients were followed up for 6 months to 10 yean, 2 patients died. 2 patients after 12 months were with bladder tumor, and given psrtial resection of the bladder. Intravesical chemotherapy after surgery was given on a regular basis. CONCLUSION The prognosis of ureteral cancer is closely related with the extent of tumor invasion and tumor stage, especially the latter is more important Imaging combined uretercacopic biopsy is the best way to diagnose ureteral cancer. Early detection, timely diagnosis and rational surgical method are essential to improve the survival rate of ureteral cancer, and it should implement inlravesical chemotherapy on a regular basis after surgery and follow-up closely.%目的 了解重症监护病房呼吸机相关肺炎的发生情况,更好的控制VAP发生.方法 采用回顾性监测的方法,调查2009年1月~2010年4月ICU接受呼吸机通气患者中VAP发病率及病原菌特点.结果 共调查183例患者,确诊VAP65例次,发病率为35.52%;VAP的发生与性别(x2=0.656,P> 0.05)不相关;机械通气时同越长,越易发生VAP;患有重症肺炎,脑血管病,重型颅脑损伤的患者VAP的发病率较高;VAP的病原菌主要是鲍氏不动杆菌,金黄色葡萄球菌,洋葱伯克霍尔德菌,铜绿假单胞菌等条件致病菌.结论 采取有效的预防控制措施,以降低VAP的发病率.

  16. RADIATION CONTAMINATION INCIDENT AT ISOLDE

    CERN Multimedia

    2000-01-01

    On 27 June 2000 three specialists were investigating a problem with the extraction electrode of the high-resolution separator (HRS) in Isolde. Whilst using an endoscope in order to have a closer look at the interior, they came into contact with radioactive dust and became contaminated. The level of contamination was low and the radiation dose received by the 3 persons was far below the effective dose limit given in the CERN Radiation Safety Manual and in the regulations of the Host States.According to the usual procedure, the Director General has set up a Fact-Finding Group and an Accident Board in order to advise him on the steps and decisions tobe taken following this incident and in particular to avoid a recurrence.

  17. The incidence of secual harassment at higher education institutions in South Africa: perceptions of academic staff

    OpenAIRE

    Pierre Joubert; Christo van Wyk; Sebastiaan Rothmann

    2011-01-01

    This article aims to investigate the perceptions of academic staff relating to the incidence of sexual harassment at higher education institutions in South Africa. The results show a relatively low incidence level of sexual harassment, with gender harassment being more prevalent than unwanted sexual attention and quid pro quo harassment. No statistically significant effect of gender, age, population group or years of service was found on the perceptions of the incidence of sexual harassment. ...

  18. Trip-timing decisions with traffic incidents

    DEFF Research Database (Denmark)

    Fosgerau, Mogens; Lindsey, Robin

    2013-01-01

    This paper analyzes traffic bottleneck congestion when drivers randomly cause incidents that temporarily block the bottleneck. Drivers have general scheduling preferences for time spent at home and at work. They independently choose morning departure times from home to maximize expected utility...... without knowing whether an incident has occurred. The resulting departure time pattern may be compressed or dispersed according to whether or not the bottleneck is fully utilized throughout the departure period on days without incidents. For both the user equilibrium (UE) and the social optimum (SO...... example is presented for illustration. Finally, the model is extended to encompass minor incidents in which the bottleneck retains some capacity during an incident....

  19. Acoustic evaluation of cementing quality using obliquely incident ultrasonic signals

    Institute of Scientific and Technical Information of China (English)

    Duan Wen-Xing; Qiao Wen-Xiao; Che Xiao-Hua; Xie Hui

    2014-01-01

    Ultrasonic cement bond logging is a widely used method for evaluating cementing quality. Conventional ultrasonic cement bond logging uses vertical incidence and cannot accurately evaluate lightweight cement bonding. Oblique incidence is a new technology for evaluating cement quality with improved accuracy for lightweight cements. In this study, we simulated models of acoustic impedance of cement and cementing quality using ultrasonic oblique incidence, and we obtained the relation between cementing quality, acoustic impedance of cement, and the acoustic attenuation coeffi cient of the A0-mode and S0-mode Lamb waves. Then, we simulated models of different cement thickness and we obtained the relation between cement thickness and the time difference of the arrival between the A0 and A0′ modes.

  20. Worldwide Incidence of Autoimmune Liver Disease

    DEFF Research Database (Denmark)

    Jepsen, Peter; Grønbæk, Lisbet; Vilstrup, Hendrik

    2015-01-01

    BACKGROUND: The variation that occurs in the incidence patterns of autoimmune liver diseases may provide insight into the risk factors causing the diseases. We systematically reviewed studies on the incidence of autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), primary sclerosing...... England. Most studies of PSC found incidence rates around 1 per 100,000 population per year, but there were no incident cases among 100,000 Alaska natives during the period 1984-2000. The incidence of IAC remains unknown. CONCLUSIONS: The incidence of the autoimmune liver diseases is around 1-2 per 100......,000 population per year for each disease. The variation in incidence over time and place suggests that there are differences in the prevalence of risk factors for the diseases, but the studies used different methods and so it is difficult to draw firm conclusions. We recommend that groups of investigators...

  1. Cancer incidence in blood transfusion recipients

    DEFF Research Database (Denmark)

    Hjalgrim, Henrik; Edgren, Gustaf; Rostgaard, Klaus;

    2007-01-01

    , the standardized incidence ratios for cancers of the tongue, mouth, pharynx, esophagus, liver, and respiratory and urinary tracts and for squamous cell skin carcinoma remained elevated beyond 10 years after the transfusion. CONCLUSIONS: The marked increase in cancer risk shortly after a blood transfusion may......BACKGROUND: Blood transfusions may influence the recipients' cancer risks both through transmission of biologic agents and by modulation of the immune system. However, cancer occurrence in transfusion recipients remains poorly characterized. METHODS: We used computerized files from Scandinavian...... blood banks to identify a cohort of 888,843 cancer-free recipients transfused after 1968. The recipients were followed from first registered transfusion until the date of death, emigration, cancer diagnosis, or December 31, 2002, whichever came first. Relative risks were expressed as ratios...

  2. Using mortality data to estimate radiation effects on breast cancer incidence

    International Nuclear Information System (INIS)

    In this paper we combine Japanese data on radiation exposure and cancer mortality with U.S. data on cancer incidence and lethality to estimate the effects of ionizing radiation on cancer incidence. The analysis is based on the mathematical relationship between the mortality rate and the incidence and lethality rates, as well as on statistical models that relate Japanese incidence rates to U.S. incidence rates and radiation risk factors. Our approach assumes that the risk of death from causes other than the cancer does not depend on whether or not the cancer is present, and among individuals with the cancer, the risk of death attributable to the cancer is the same in Japan and the U.S. and is not affected by radiation exposure. In particular, we focus on the incidence of breast cancer in Japanese women and how this incidence is affected by radiation risk factors. The analysis uses Japanese exposure and mortality data from the Radiation Effects Research Foundation study of atomic bomb survivors and U.S. incidence and lethality data from the Surveillance, Epidemiology, and End Results Registry. Even without Japanese incidence data, we obtain reasonable estimates of the incidence of breast cancer in unexposed Japanese women and identify the radiation risk factors that affect this incidence. Our analysis demonstrates that the age at exposure is an important risk factor, but that the incidence of breast cancer is not affected by the city of residence (Nagasaki versus Hiroshima) or the time since exposure

  3. Behavioral Traits and Airport Type Affect Mammal Incidents with U.S. Civil Aircraft

    Science.gov (United States)

    Schwarz, Kristin B.; Belant, Jerrold L.; Martin, James A.; DeVault, Travis L.; Wang, Guiming

    2014-10-01

    Wildlife incidents with aircraft cost the United States (U.S.) civil aviation industry >US1.4 billion in estimated damages and loss of revenue from 1990 to 2009. Although terrestrial mammals represented only 2.3 % of wildlife incidents, damage to aircraft occurred in 59 % of mammal incidents. We examined mammal incidents (excluding bats) at all airports in the Federal Aviation Administration (FAA) National Wildlife Strike Database from 1990 to 2010 to characterize these incidents by airport type: Part-139 certified (certificated) and general aviation (GA). We also calculated relative hazard scores for species most frequently involved in incidents. We found certificated airports had more than twice as many incidents as GA airports. Incidents were most frequent in October ( n = 215 of 1,764 total) at certificated airports and November ( n = 111 of 741 total) at GA airports. Most (63.2 %) incidents at all airports ( n = 1,523) occurred at night but the greatest incident rate occurred at dusk (177.3 incidents/hr). More incidents with damage ( n = 1,594) occurred at GA airports (38.6 %) than certificated airports (19.0 %). Artiodactyla (even-toed ungulates) incidents incurred greatest (92.4 %) damage costs ( n = 326; US51.8 million) overall and mule deer ( Odocoileus hemionus) was the most hazardous species. Overall, relative hazard score increased with increasing log body mass. Frequency of incidents was influenced by species relative seasonal abundance and behavior. We recommend airport wildlife officials evaluate the risks mammal species pose to aircraft based on the hazard information we provide and consider prioritizing management strategies that emphasize reducing their occurrence on airport property.

  4. 糖尿病视网膜病变玻璃体视网膜术后高眼压发生率及相关因素%Incidence rate and related factors of intraocular pressure after vitro-retinal surgery for patients with diabetic retinopathy

    Institute of Scientific and Technical Information of China (English)

    李旭青; 蔡晓峰; 庹瑶; 陈康

    2014-01-01

    目的:探讨糖尿病视网膜病变( DRP)行玻璃体视网膜术后高眼压的发生率及相关因素。方法选择行玻璃体视网膜术治疗的DRP患者986例(1326眼)为研究对象。分析术后高眼压的发生率,并且对比分析不同类型、不同分级、术前是否合并黄斑脱离、行硅油/C3F8充填、术中行全/补充视网膜光凝、是否晶状体切除患者高眼压发生率的差异。结果1326眼术后发生高眼压共计368例(27.8%)。增生型DRP患者术后高眼压发生率(34.0%)显著高于非增生型(17.2%)(χ2=30.648,P=0.000);DRP D级高眼压发生率为34.1%,显著高于 B 级(20.8%)(χ2=16.348,P =0.001);术前合并黄斑脱离患者高眼压发生率(30.4%)显著高于无黄斑脱离患者(22.7%)(χ2=8.834,P =0.003);术中充填硅油患者(39.1%)显著高于填充 C3F8患者(24.0%)(χ2=28.088,P=0.000);术中全视网膜光凝者(32.8%)显著高于补充光凝患者(16.8%)(χ2=21.159,P=0.000);术中行晶状体切除者(40.5%)显著高于无晶状体切除者(25.9%)(χ2=15.532,P=0.0001)。结论 DRP患者玻璃体视网膜术后高眼压的发生率高,并且与DRP类型、分级、术前合并黄斑脱离、术中填充物、视网膜光凝、晶状体切除等相关。%Objective To explore the incidence rate and related factors of high intraocular pressure after vitro-retinal surgery for patients with diabetic retinopathy(DRP). Methods The 986 patients(1 326 eyes) with DRP arranged vitro-retinal surgery were studied. The inci-dence rate of intraocular pressure was analyzed between different types,grades,complicated with macular detachment,filled with silicone oil/C3F8,total/supplementary retina photo-coagulation and crystalline lens excision. Results The incidence rate of high intraocular pressure was 27. 8%(368/1 326). The incidence rate of high intraocular pressure of proliferative DRP (34. 0%) was obviously higher than non-pro-liferative DRP (17. 2%)(χ2 =30. 648,P=0. 000),and higher in DRP D

  5. Computer Simulation for Emergency Incident Management

    Energy Technology Data Exchange (ETDEWEB)

    Brown, D L

    2004-12-03

    This report describes the findings and recommendations resulting from the Department of Homeland Security (DHS) Incident Management Simulation Workshop held by the DHS Advanced Scientific Computing Program in May 2004. This workshop brought senior representatives of the emergency response and incident-management communities together with modeling and simulation technologists from Department of Energy laboratories. The workshop provided an opportunity for incident responders to describe the nature and substance of the primary personnel roles in an incident response, to identify current and anticipated roles of modeling and simulation in support of incident response, and to begin a dialog between the incident response and simulation technology communities that will guide and inform planned modeling and simulation development for incident response. This report provides a summary of the discussions at the workshop as well as a summary of simulation capabilities that are relevant to incident-management training, and recommendations for the use of simulation in both incident management and in incident management training, based on the discussions at the workshop. In addition, the report discusses areas where further research and development will be required to support future needs in this area.

  6. Incidence of injury and physical performance adaptations during military training

    DEFF Research Database (Denmark)

    Rosendal, Lars; Langberg, Henning; Skov-Jensen, Arne;

    2003-01-01

    Strenuous physical activity, such as military training, is known to demand a high degree of physical performance and to cause overuse injuries. However, the exact relation between injury incidence and physical fitness level and the influence of military training on measures of functional...

  7. Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors

    OpenAIRE

    Haggar, Fatima A.; Boushey, Robin P.

    2009-01-01

    In this article, the incidence, mortality, and survival rates for colorectal cancer are reviewed, with attention paid to regional variations and changes over time. A concise overview of known risk factors associated with colorectal cancer is provided, including familial and hereditary factors, as well as environmental lifestyle-related risk factors such as physical inactivity, obesity, smoking, and alcohol consumption.

  8. 1976 Hanford americium exposure incident: overview and perspective

    International Nuclear Information System (INIS)

    Salient features of the 1976 Hanford americium exposure incident are discussed. Comparisons are made with previous human and animal exposure data, and conclusions drawn relative to the injured workman, to health physics practices, and to the adequacy of current exposure limits

  9. Epidemiology of Eating Disorders : Incidence, Prevalence and Mortality Rates

    NARCIS (Netherlands)

    Smink, Frederique R. E.; van Hoeken, Daphne; Hoek, Hans W.

    2012-01-01

    Eating disorders are relatively rare among the general population. This review discusses the literature on the incidence, prevalence and mortality rates of eating disorders. We searched online Medline/Pubmed, Embase and PsycINFO databases for articles published in English using several keyterms rela

  10. Statistical issues in modelling radiation effects on disease incidence

    International Nuclear Information System (INIS)

    The author attempts to outline an overview of some models which have proven useful in recent work with radiation effects data. Topics addressed are mathematical models for radiation effects on disease incidence, modelling of background rates, relative versus excess risk models, dose-response effects, dose effect modification (sex and age at exposure), temporal variation in risks. (Author)

  11. Review of the prevalence and incidence of eating disorders

    NARCIS (Netherlands)

    Hoek, HW; van Hoeken, D

    2003-01-01

    Objective: To review the literature on the incidence and prevalence of eating disorders. Methods: We searched Medline using several key terms relating to epidemiology and eating disorders and we checked the reference lists of the articles that we found. Special attention has been paid to methodologi

  12. The effects of vaccination, the incidence of the target diseases

    NARCIS (Netherlands)

    Hof S van den; Conyn-van Spaendonck MAE; Melker HE de; Geubbels ELPE; Suijkerbuijk AWM; Talsma E; Plantinga AD; Rumke HC; CIE

    1998-01-01

    As a result of improved socio-economic state and related hygiene, and the introduction of the National Vaccination Programme (RVP), the incidence of the target diseases of the RVP is low nowadays. Insight in the occurrence of the diseases remains necessary in order to be able to signal possible seco

  13. Increasing incidence of celiac disease in a North American population

    Science.gov (United States)

    Ludvigsson, Jonas F.; Rubio-Tapia, Alberto; van Dyke, Carol T.; Melton, L. Joseph; Zinsmeister, Alan R.; Lahr, Brian D.; Murray, Joseph A.

    2013-01-01

    OBJECTIVES The prevalence of celiac disease (CD) varies greatly, potentially because of incomplete ascertainment of cases and small study samples with limited statistical power. Previous reports indicate that the incidence of CD is increasing. We examined the prevalence of CD in a well-defined US county. METHODS Population-based study in Olmsted County, Minnesota, US. Using the infrastructure of the Rochester Epidemiology Project, medical, histopathology, and CD serology records were used to identify all new cases of CD in Olmsted County since 2000. Age- and sex-specific and adjusted (to the US white 2000 population) incidence rates for CD were estimated. Clinical presentation at diagnosis was also assessed. RESULTS Between 2000 and 2010, 249 individuals (157 female or 63%, median age 37.9 years) were diagnosed with CD in Olmsted County. The overall age- and sex-adjusted incidence of CD in the study period was 17.4 (95% confidence interval [CI] = 15.2–19.6) per 100,000 person-years, increasing from 11.1 (95% CI=6.8–15.5) in 2000–2001 to 17.3 (95% CI=13.3–21.3) in 2008–2010. The temporal trend in incidence rates was modeled as a two-slope pattern, with the incidence leveling off after 2004. Based on the two classic CD symptoms of diarrhea and weight loss, the relative frequency of classical CD among incident cases decreased over time between 2000 and 2010 (p=0.044). CONCLUSION The incidence of CD has continued to increase in the past decade in a North American population. PMID:23511460

  14. Rising incidence of childhood type 1 diabetes in Montenegro

    Directory of Open Access Journals (Sweden)

    Samardžić Mira

    2016-01-01

    Full Text Available Introduction. The incidence rate of childhood type1 diabetes continues to rise across Europe by an average of approximately 3-4% per annum. Objective. The aim of this study was to examine incidence and trends of type 1 diabetes in children aged 0-14 years in Montenegro from 1997 to 2011. Methods. This was a prospective study. Primary case ascertainment was from a diabetes register, and a secondary independent data source was from hospital notifications. Case ascertainment was 100% complete using the capture-recapture method. Standardized incidence rates were calculated and trends estimated using the Poisson regression. Results. A total of 298 children (157 boys and 141 girls were diagnosed with type 1 diabetes before 15 years of age during 1997-2011. The mean age-standardized incidence was 15.0/100,000 persons (95% CI: 12.3-17.6 during this period, increasing from 11.7/100,000 in 1997 to 18.8/100,000 in 2011. The agespecific rates per 100,000 persons per year were 10.7, 17.2, and 18.2 at ages 0-4 years, 5-9 years, and 10-14 years, respectively. A significant linear trend in incidence (p = 0.002 has been observed over time, with an average annual increase of 4.2%. The increase in incidence was present in both genders, with the largest relative increase in the 0-4 years age group for boys (11.0%; p = 0.006. Conclusion. The incidence of type 1 diabetes in Montenegro children continues to increase. We need further monitoring and additional research in order to explain the cause.

  15. Trends in incidence of gallbladder cancer – Indian scenario

    Directory of Open Access Journals (Sweden)

    Nandagudi Srinivasa Murthy

    2011-01-01

    Full Text Available Nandagudi Srinivasa Murthy1, Dinesh Rajaram1, MS Gautham1, NS Shivraj1, Sreekantaiah Pruthvish1, Preethi Sara George2, Aleyamma Mathew21MS Ramaiah Medical College, Bangalore, Karnataka, India; 2Regional Cancer Centre, Thiruvananthapuram, Kerala, IndiaBackground: Reports of increasing incidence rates of gallbladder cancer in several areas in India prompted the analysis of time trends. The present communication reports its geographic and gender distribution and trends in occurrence of this disease over time.Materials and methods: The data published in Cancer Incidence in Five Continents for various Indian registries for different periods and/or publication by the individual registries served as the source material. Mean annual percentage change (MAPC in incidence rates was computed using relative difference between two time periods (earliest and latest, and estimation of annual percent change (EAPC was computed by log-linear regression model.Results: In 1998–2006, incidence rates of gallbladder cancer (age-standardized rate, ASR were high in Delhi and Kamrup ((3.6 and 7.4 and (5.3 and 14.3 per 105 person years in males and females, respectively and lowest in Aurangabad, 0.0 in both genders. The incidence rate revealed an increase in all registries. MAPC in ASR ranged from 1.0% to 8.10%. EAPC for Mumbai, Chennai, and Bangalore for the period 1983–2002 revealed statistically significant increase in crude, age-standardized, and truncated rate (TR (35–64 years incidence rates. The largest EAPC in ASR was in Chennai (almost 6.0% in both genders and smallest in Mumbai (3.5% and 2.1% in males and females, respectively.Conclusions: Statistically significant increase in gallbladder cancer incidence rates has been reported for Mumbai, Chennai, and Bangalore. Further studies are required in identifying factors that may be operative in etiology of cancer of gallbladder.Keywords: gallbladder cancer, trend, Indian scenario, calendar year

  16. Economic impact profiling of CBRN events: focusing on biological incidents.

    Science.gov (United States)

    Cavallini, Simona; Bisogni, Fabio; Mastroianni, Marco

    2014-12-01

    Chemical, biological, radiological and nuclear (CBRN) incidents, both caused accidentally by human error or natural/technological events and determined intentionally as criminal/malicious/terroristic acts, have consequences that could be differently characterized. In the last years many efforts to analyze the economic impact of terrorist threat have been carried out, while researches specifically concerning CBRN events have not been extensively undertaken. This paper in particular aims at proposing a methodological approach for studying macro-level economic impact profiles of biological incidents caused by weaponized and non-weaponized materials. The suggested approach investigates the economic consequences of biological incidents according to two main dimensions: type of large-scale effect and persistence of effect. Biological incident economic impacts are analyzed taking into account the persistence of effect during time as short-term impact (i.e. immediately after the incident), medium-term impact (i.e. by a month) and long-term impact (i.e. by years). The costs due to preventive countermeasure against biological threats (e.g. prevention, protection and preparedness expenses) are not taken into account. To this purpose, information on the key features of past biological incidents can be used as case studies to try to build impact profiles taking into account the proposed two main dimensions. Consequence management and effect mitigation of CBRN emergencies and disasters may benefit from an ex ante definition of the impact profiling related to this kind of incidents. The final goal of this paper is to define an approach to organize information on possible biological events according to their impact profile for supporting more effective and efficient first responders' prompt actions and policy makers' strategic decisions after the event occurrence.

  17. Lung cancer incidence and risk factors

    International Nuclear Information System (INIS)

    The possibility of developing lung cancer (lc) as a consequence of inhaling hot particles from the Chernobyl accident is discussed. The risk from various factors is reviewed in order to assess the rate of contribution for any of them to carcinogenic process. The conclusions are based on data reported by National Centre of Oncology, Sofia (BG). A total of 2873 new cases have been recorded in 1990. The data for the period 1970-1990 show a crude increase for males and tend to stabilization for females. The similar pattern is obtained in other countries and geographic areas with steady rise of lc cases with about 0.5% per year. The contribution of particular risk factor and its interaction with other factors is assessed on the basis of large number of epidemiologic and experimental studies. The risk of cigarette smoking, as the principal cause for lc, is discussed in various aspects - age, duration, possible dropping the habit. The assessment of another risk factor - exposure to relatively high doses of natural radon daughter products - is more complicated. As an occupational hazard in uranium mines radon and its progeny reveals an increase in excess lc incidence. Regarding radon and its daughters as an environmental risk factor in dwellings, no clear positive relationship between exposure and lc incidence has been observed. In this case the assessment for population living in areas with higher concentration of radon products have to rely on data from uranium mines. Non radiation factors as asbestos, ethers, chromates, metallic iron, nickel, beryllium and arsenic, are also considered. The combined effect of all these factors, as well as of pathological cell processes, viruses, malfunctions of immune system, is mentioned as well. The possibility of interpreting the findings from epidemiological studies within the framework of theoretical multistage models of carcinogenic process is pointed out. (author)

  18. Incidence of childhood psychiatric disorders in India

    OpenAIRE

    Malhotra, Savita; Kohli, Adarsh; Kapoor, Mehak; Pradhan, Basant

    2009-01-01

    Background: Studies on incidence of childhood mental disorders are extremely rare globally and there are none from India. Incidence studies though more difficult and time consuming, provide invaluable information on the pattern and causes of occurrence of mental disorders allowing opportunity for early intervention and primary prevention. Aim: This study aimed at estimating the incidence of psychiatric disorders in school children. Materials and Methods: A representative sample of school chil...

  19. Hypothyroidism incidence in and around pregnancy

    DEFF Research Database (Denmark)

    Andersen, Stine Linding; Carle, Allan; Olsen, Jørn;

    2016-01-01

    -2010 (overall IR 92.3/100,000/year) and 1,572 women developed hypothyroidism in the period from 2 years before to 2 years after birth of the first child birth in the study period. The incidence of hypothyroidism decreased during the pregnancy (incidence rate ratio (IRR) versus overall IR in the rest...... of hypothyroidism in and around pregnancy. The incidence declined during pregnancy followed by a sharp increase postpartum. Notably, hypothyroidism as opposed to hyperthyroidism showed no early pregnancy peak....

  20. Emulating Nonreciprocity with Spatially Dispersive Metasurfaces Excited at Oblique Incidence

    Science.gov (United States)

    Pfeiffer, Carl; Grbic, Anthony

    2016-08-01

    Ultrathin metasurfaces supporting transverse surface currents provide extreme electromagnetic wave front and polarization control. Here, it is shown that adding longitudinal (normal) surface currents significantly expands the scope of electromagnetic phenomena that can be engineered with reciprocal materials. In particular, these metasurfaces are inherently spatially dispersive, which allows them to emulate nonreciprocal phenomena. It is analytically shown that spatially dispersive metasurfaces are effectively self-biased by the transverse momentum of the incident wave front. Long-standing notions of what makes a metasurface reciprocal are reinvestigated, and generalized reciprocity relations are derived. Several metasurfaces are designed that imitate Faraday rotation and optical isolation when illuminated with obliquely incident plane waves and normally incident vortex beams. These new surfaces break the inherent symmetry of previous metasurface designs, enabling low-profile devices with unprecedented functionality.

  1. Epidemiology, Incidence and Mortality of Breast Cancer in Asia.

    Science.gov (United States)

    Ghoncheh, Mahshid; Momenimovahed, Zohre; Salehiniya, Hamid

    2016-01-01

    Breast cancer is the most common malignancy in women around the world. Information on the incidence and mortality of breast cancer is essential for planning health measures. This study aimed to investigate the incidence and mortality of breast cancer in the world using age-specific incidence and mortality rates for the year 2012 acquired from the global cancer project (GLOBOCAN 2012) as well as data about incidence and mortality of the cancer based on national reports. It was estimated that 1,671,149 new cases of breast cancer were identified and 521,907 cases of deaths due to breast cancer occurred in the world in 2012. According to GLOBOCAN, it is the most common cancer in women, accounting for 25.1% of all cancers. Breast cancer incidence in developed countries is higher, while relative mortality is greatest in less developed countries. Education of women is suggested in all countries for early detection and treatment. Plans for the control and prevention of this cancer must be a high priority for health policy makers; also, it is necessary to increase awareness of risk factors and early detection in less developed countries. PMID:27165207

  2. Nontuberculous mycobacteria: incidence in Southwest Ireland from 1987 to 2000.

    LENUS (Irish Health Repository)

    Kennedy, M P

    2012-02-03

    SETTING: The Southwest of Ireland (Counties Cork and Kerry) 1987-2000, average population 549,500. OBJECTIVE: Nontuberculous mycobacteria (NTM) cause significant morbidity worldwide and the study of epidemiology and characteristics helps in their prevention and treatment. This study was performed to determine the incidence of NTM disease in comparison to Mycobacterium tuberculosis (M. tuberculosis) and Mycobacterium bovis (M. bovis) in Southwest Ireland, over the above time period. DESIGN: A retrospective study was carried out in all human isolates of NTM, M. tuberculosis and M. bovis between 1987 and 2000, in the Southwest Region of Ireland. RESULTS: The mean incidence of NTM (0.4\\/100,000 population) has risen since 1995, principally of pulmonary Mycobacterium avium intracellulare complex (MAC). The annual incidence of M. tuberculosis in humans over 14 years in the same region was 971\\/100,000 population with a significant reduction since 1994 and M. bovis remained constant at 0.5\\/100,000 population. CONCLUSION: The increasing incidence of disease causing NTM noted in Southwest Ireland reflects global data and is surmised to be due to an ageing population, increased incidence related to chronic fibrotic lung disease, and environmental mycobacterial factors.

  3. Traumatic sternal fracture: Incidence, causes and CT features

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyo Weon; Kim, Young Tong; Jou, Sung Shick; Han, Jong Kyu; Bae, Won Kyung [Dept. of Radiology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan (Korea, Republic of)

    2015-05-15

    To evaluate the incidence of sternal fracture due to trauma, the CT features of sternal fractures, and the hospitalization period. The medical records and CT images of 755 patients who suffered trauma from January 2012 to August 2013 were analyzed retrospectively. We compared the incidence of sternal fracture due to various traumatic causes. We evaluated the location and shape of the sternal fracture on CT scans and the relationship between a sternal fracture and the hospitalization period. The incidence of sternal fracture was 9.27% (70/755) in all patients; 11.7% (53/453) due to a traffic accident (TA), and 5.63% (17/302) due to other causes. TA was the most frequent cause (75.71%) of a sternal fracture, fracture incidences after a TA differed by traumatic cause (p < 0.05). Among sternal fractures, the body was the most commonly involved (68.57%), one wall was limited (32.85%), and anteroposterior length increased (7.14%). Body fractures involving two or more segments included 33.33% of the cases. The hospitalization period was not related with sternal fracture (p = 0.30). Fracture was more frequent after a TA than due to other causes. Fracture incidences after a TA depended on the traumatic causes. Involvement of two or more segments and one wall-limitation were common among sternal fractures. Sternal fractures occurred even in slightly injured patients.

  4. Socioeconomic Inequalities in Stroke Incidence Among Migrant Groups

    DEFF Research Database (Denmark)

    Agyemang, Charles; van Oeffelen, AA; Nørredam, Marie Louise;

    2014-01-01

    Background and Purpose—Low socioeconomic status has been linked to high incidence of stroke in industrialized countries; therefore, reducing socioeconomic disparities is an important goal of health policy. The evidence on migrant groups is, however, limited and inconsistent. We assessed socioecon......Background and Purpose—Low socioeconomic status has been linked to high incidence of stroke in industrialized countries; therefore, reducing socioeconomic disparities is an important goal of health policy. The evidence on migrant groups is, however, limited and inconsistent. We assessed...... socioeconomic inequalities in relation to stroke incidence among major ethnic groups in the Netherlands. Methods—A nationwide register-based cohort study was conducted (n=2 397 446) between January 1, 1998, and December 31, 2010, among ethnic Dutch and ethnic minority groups. Standardized disposable household...... income was used as a measure of socioeconomic position. Results—Among ethnic Dutch, the incidence of stroke was higher in the low-income group than in the high-income group (adjusted hazard ratio, 1.18; 95% confidence interval, 1.16–1.20). Similar socioeconomic inequalities in stroke incidence were found...

  5. Spatial patterns in breast cancer incidence in north-west Lancashire

    OpenAIRE

    Rigby, Janette E; Gatrell, Anthony C.

    2000-01-01

    Breast cancer is a disease whose incidence is increasing in both developed and developing countries, but whose complex aetiology is not clearly understood. Recent research suggests that the environment may be an important factor, hence and investigation into spatial patterning of incidence could inform such research. We use data on incidence in north-west Lancashire and apply some techniques for exploratory spatial analysis, at a variety of spatial scales. Issues relating to the use of inc...

  6. Laboratory Study on the Interaction Between Regular Obliquely Incident Waves and Vertical Walls

    Institute of Scientific and Technical Information of China (English)

    李玉成; 董国海; 孙昭晨; 徐双全; 毛恺; 牛恩宗

    2001-01-01

    The characteristics of wave forces are studied based on physical model tests with regular waves. The ratio ofobliquely incident wave forces to normally incident wave forces on unit length of a vertical wall is related with variousfactors. A linear reduction of the mean force of obliquely incident waves is confirmed with an increase in the relativecaisson length. Also the characteristics of reflection coefficient of diagonal waves are discussed.

  7. Incidence and Epidemiology of Patellar Fractures

    DEFF Research Database (Denmark)

    Larsen, Peter; Court-Brown, Charles M; Vedel, Julie Odgaard;

    2016-01-01

    The literature lacks large-scale, up-to-date, population-based epidemiology studies on the incidence of patellar fractures based on complete populations. The purpose of this study was to provide up-to-date information concerning the incidence of patellar fractures in a large and complete population...

  8. The Incidence of Ankle Sprains in Orienteering.

    Science.gov (United States)

    Ekstrand, Jan; And Others

    1990-01-01

    Investigates relationship between ankle sprains and participation time in competitive orienteering. Examined 15,474 competitors in races in the Swedish O-ringen 5-day event in 1987. Injuries requiring medical attention were analyzed, showing 137 (23.9 percent) ankle sprains. Injury incidence was 8.4/10,000 hours. Incidence of ankle sprains was…

  9. Linux Incident Response Volatile Data Analysis Framework

    Science.gov (United States)

    McFadden, Matthew

    2013-01-01

    Cyber incident response is an emphasized subject area in cybersecurity in information technology with increased need for the protection of data. Due to ongoing threats, cybersecurity imposes many challenges and requires new investigative response techniques. In this study a Linux Incident Response Framework is designed for collecting volatile data…

  10. Incidence and predictors of coronary stent thrombosis

    DEFF Research Database (Denmark)

    D'Ascenzo, Fabrizio; Bollati, Mario; Clementi, Fabrizio;

    2013-01-01

    Stent thrombosis remains among the most feared complications of percutaneous coronary intervention (PCI) with stenting. However, data on its incidence and predictors are sparse and conflicting. We thus aimed to perform a collaborative systematic review on incidence and predictors of stent...... thrombosis....

  11. 生活方式因素健康分值与男性癌症发病的公共卫生学评价%Lifestyle-related factors and cancer incidence in men: a public health assessment based on a 'healthy lifestyle score'

    Institute of Scientific and Technical Information of China (English)

    唐认桥; 郑苇; 李泓澜; 舒晓鸥; 项永兵

    2013-01-01

    目的 探讨生活方式因素及健康分值对上海市成年男性恶性肿瘤发病的影响.方法 利用2002-2006年上海市男性健康队列(SMHS)的基线调查资料,至2009年12月最近一次随访,男性队列累积收集恶性肿瘤新病例2033例.根据吸炯(吸烟计0分,不吸烟计1分)、饮酒(≥1 drinks/d计0分,<1drinks/d计1分)、BMI(<18.5 kg/m2或≥28 kg/m2计0分,18.5~27.9 kg/m2计1分)、体力活动(<54 Met-hours/week计0分,≥54 Met-hours/week计1分)、蔬菜水果摄入(<451g/d计0分,≥451 g/d计1分)五种常见生活方式因素建立健康生活方式分值表,分值分布范围为0(最不健康生活方式)至5(最健康生活方式)分.采用Cox回归模型估计健康生活方式分值与癌症的相对危险度(HR)及其95%CI.结果 相对于得分为0或者1分的人群组,得分为2~5分人群组发生癌症的HR值分别为0.77(95%CI:0.66 ~ 0.90)、0.67(95%CI:0.58 ~ 0.78)、0.56(95%CI:0.47 ~ 0.65)、0.51(95%CI:0.42 ~ 0.62).健康生活方式得分少于3项的人群癌症发病归因危险度百分比(PAR%)为10.4%(95%CI:7.3% ~ 13.5%).结论 不吸烟、不过量饮酒,保持正常体型,适当体育锻炼及多食蔬菜水果可较显著降低癌症的发生,保持健康的生活方式具有显著的公共卫生学效益.%Objective To evaluate the effects of combined lifestyle-related factors and risk of cancer incidence among adult men in urban Shanghai.Methods Information was obtained from 60 817 men in the Shanghai Men' s Health Study (2002-2006) program and 2033 incident cancers who were confirmed at the end of 2009.A healthy lifestyle score (HLS) system was developed,based on five lifestyle-related factors,and participants were scored one point for each of the healthy behaviour:never smoked,alcohol intake less than 1 drink/day,under normal weight range (18.5-27.9 kg/m2),physical activity (≥ 54 Met-hours/week),fruit and vegetable intake ≥451 g/day,the else would

  12. Asbestos exposure and mesothelioma incidence and mortality in Bulgaria.

    Science.gov (United States)

    Vangelova, Katya; Dimitrova, Irina

    2016-06-01

    Bulgaria totally banned the import, production and use of asbestos in 2005, but produced and used asbestos products during the last 3-4 decades of the 20th century. The aim of this study was to follow the incidence and mortality of mesothelioma in Bulgaria in relation to past occupational exposures. A literature search between 1960 and 2014 was conducted to obtain information on asbestos consumption, occupational exposure and asbestos-related diseases (ARDs). Data on registered mesotheliomas were provided by the National Cancer Register and data for recognized occupational ARDs were provided by the National Social Security Institute. An increase in the incidence of mesothelioma from 5 to 58 from 1993 to 2013, with 666 cases in the 21-year period, was registered. Incidence, mortality rates, deaths and male-to-female ratios and were lower in comparison to industrialized countries. The increase in mesothelioma incidence is considered as a consequence of more recent production and use of asbestos and asbestos products and the high occupational exposure between 1977 and 1989, while the lower rate of mesothelioma deaths and male-to-female ratio need to be investigated further. PMID:27180335

  13. Analysis of the incidence of sensory integrative dysfunction and its related factors in 1 008 school-age children in Heze city%菏泽市城区学龄儿童1008例感觉统合失调发生率及其相关因素调查

    Institute of Scientific and Technical Information of China (English)

    吴效普; 赵海英

    2004-01-01

    AIM:To investigate the incidence of sensory integrative dysfunction(SID) and its related factors in school-age children in Heze city. METHODS:A total of 1 008 children at the ages from 6 to 10 years were studies by means of cluster sampling using Beijing SID evaluation scale and the results analyzed statistically. RESULTS:Of all the 1 008 children,the total incidence of SID was 35.52% (358/1008),including 236(23.41% ) mild and 122(12.10% ) severe cases.The incidence was 43.1% (218/506) in boys and 27.9% (140/502) in girls(χ 2=25.404,P< 0.005).The children aged 6- 7 years had lower incidence than in the children aged 8- 10 years(χ 2=9.726,P< 0.01).The incidence of SID was 27.1% (91/336) in children with good academic performance and 51.5% (104/202) in those with poor performance,showing a significant difference(χ 2=49.72,P< 0.005).A rate of 23.6% of the SID students have parents with college education,and 17.9% of the SID students' parents had senior high school or technical secondary school education,as compared with the parents of 38.5% of the students receiving junior high school education or below(χ 2=5.874,P< 0.05).Of all the children with SID,34.4% (123/358) used to have neonatal hypoxic ischemic encephalopathy (HIE). CONCLUSION:The incidence of SID in school-age children is closely associated with sex,age,parents' education background,academic performance and neonatal HIE.%目的:了解本市的学龄儿童感觉统合失调( sensory integration dysfunction,SID)的发生率及造成感觉统合失调的有关因素. 方法:采用北京感觉统合失调评定表,对 6~ 10岁 1 008例在校儿童进行整群抽样调查,所获数据经χ 2检验. 结果:感觉统合失调发生率为 35.52%( 358/1 008),其中轻度 23.41%( 236/1 008),重度 12.10%( 122/1 008);男童发生率为 43.1%( 218/506),女童发生率为 27.9%( 140/502),男高于女χ 2=25.404(P< 0.005).六七岁组感觉统合失调率低于 8~ 10岁组(χ 2=9.726,P< 0.01)学

  14. HIV incidence and factor related to lost-to-follow-up among men who have sex with men in Harbin, Heilongjiang%哈尔滨市男男性行为人群HIV新发感染及失访影响因素分析

    Institute of Scientific and Technical Information of China (English)

    惠珊; 李一; 闫红梅; 郭巍; 佟雪; 王开利

    2015-01-01

    Objective To estimate the incidence of human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) and its related factors in Harbin,Heilongjiang province.Methods A total of 661 MSM were recruited at baseline study from April to June 2013,and followed at 6 months,12 months,and 18 months periods,respectively.Face to face questionnaire interviews were conducted and venous blood was collected for HIV testing among these people.Univariate logistic regression model was used to identify the factors associated with lost-to-follow-up in the cohort.Results At the end of 18-month follow-up period,the HIV incidence density in the cohort was 4.23/100 person year (95% CI:2.91/100 person year-5.93/100 person year),with the follow-up rate of loss as 15.4%.Factors as failed to receiving the intervention programs,being at older age,with higher education level and receiving no HIV testing in this MSM community,were related to the loss of follow-up.Conclusion The HIV incidence rate was high among the MSM in Harbin.MSM community based cohort study could improve the efficiency on the study for the problems of follow-up.%目的 了解黑龙江省哈尔滨市MSM人群中HIV新发感染率及失访影响因素.方法 2013年4-6月在哈尔滨市MSM人群中招募661人进行前瞻性调查,分别于6、12、18个月进行随访,入组及随访时均对调查对象进行面对面问卷调查,并采集静脉血进行HIV抗体检测,计算发病密度.利用logistic回归模型探讨MSM人群队列研究中失访的影响因素.结果 随访至18个月,调查对象HIV发病密度为4.23/100人年(95%CI:2.91/100人年~5.93/100人年),队列失访率为15.4%.未接受过干预、高年龄组、低学历者及非男男同志社区组织的研究对象易失访.结论 MSM人群HIV新发感染率较高,积极依托社区组织能提高该人群随访率.

  15. Liver cancer incidence and mortality in China, 2009

    Institute of Scientific and Technical Information of China (English)

    Wan-Qing Chen; Rong-Shou Zheng; Si-Wei Zhang

    2013-01-01

    Liver cancer is a common cancer and a leading cause of cancer deaths in China.To aid the government in establishing a control plan for this disease,we provided real-time surveillance information by analyzing liver cancer incidence and mortality in China in 2009 reported by the National Central Cancer Registry.Liver cancer incidence and cases of death were retrieved from the national database using the ICD-10 topography code "C22".Crude incidence and mortality were calculated and stratified by sex,age,and location (urban/rural).China's population in 1982 and Segi (world) population structures were used for age-standardized rates.In cancer registration areas in 2009,the crude incidence of liver cancer was 28.71/100,000,making it the fourth most common cancer in China,third most common in males,and fifth most common in females.The crude mortality of liver cancer was 26.04/100,000,making it the second leading cause of cancer death in China and urban areas and the third leading cause in rural areas.Incidence and mortality were higher in males than in females and were higher in rural areas than in urban areas.The age-specific incidence and mortality were relatively low among age groups under 30years but dramatically increased and peaked in the 80-84 years old group.These findings confirm that liver cancer is a common and fatal cancer in China.Primary and secondary prevention such as health education,hepatitis B virus vaccination,and early detection should be carried out both in males and females,in urban and rural areas.

  16. Nasopharyngeal carcinoma incidence and mortality in China in 2009

    Institute of Scientific and Technical Information of China (English)

    Zhi-Jian Xu; Rong-Shou Zheng; Si-Wei Zhang; Xiao-Nong Zou; Wan-Qing Chen

    2013-01-01

    Nasopharyngeal carcinoma (NPC) is rare globally but common in China and exhibits a distinct ethnic and geographic distribution.In 2009,the National Central Cancer Registry in China provided real-time surveillance information on NPC.Individual NPC cases were retrieved from the national database based on the ICD-10 topography code C11.The crude incidence and mortality of NPC were calculated by sex and location (urban/rural).China's population in 1982 and Segi's world population structures were used to determine age-standardized rates.In regions covered by the cancer registries in 2009,the crude incidence of NPC was 3.61/100,000 (5.08/100,000 in males and 2.10/100,000 in females; 4.19/100,000 in urban areas and 2.42/100,000 in rural areas).Age-standardized incidences by Chinese population (ASIC) and Segi's world population (ASIW) were 2.05/100,000 and 2.54/100,000,respectively.The crude mortality of NPC was 1.99/100,000 (2.82/100,000 in males and 1.14/100,000 in females; 2.30/100,000 in urban areas and 1.37/100,000 in rural areas).The age-standardized mortalities by Chinese population (ASMC) and world population (ASMW) were 1.04/100,000 and 1.35/100,000,respectively.The incidence and mortality of NPC were higher in males than in females and higher in urban areas than in rural areas.Both agespecific incidence and mortality were relatively low in persons younger than 30 years old,but these rates dramatically increased.Incidence peaked in the 60-64 age group and mortality peaked in the over 85 age group.Primary and secondary prevention,such as lifestyle changes and early detection,should be carried out in males and females older than 30 years of age.

  17. Cancer estimation of incidence and survival in Algeria 2014

    Directory of Open Access Journals (Sweden)

    Hamdi Cherif M

    2015-10-01

    Full Text Available Cancer is one of the major public health problems in Algeria. In the last 25 years, a significant increase in the incidence of the major types of cancers has been observed in both sexes. Moreover, the 5-year survival rate is low for the severe tumors due to a difficulty in access to cancer care and an incomplete health care framework. Cancer Registry of Setif, Algeria, has been recording cancer incidence, mortality, and survival since 1986 in collaboration with International Agency for Research on Cancer (IARC of Lyon. Cancer Registry of Setif is being a source of information for cancer planning and corresponding surveillance in the National Cancer Plan 2015-2019, starting in January 2015. Data is recorded by means of CanReg 5 software. This software is developed and provided by the International Agency for Research on Cancer (IARC of Lyon. It is designed specifically for cancer registration, and standardized to capture, control, and process the data. Estimation of cancer incidence in Algeria and survival rates are very important for surveillance, control, and planning of care. In men the incidence of lung, colorectal, bladder, prostate, and laryngeal cancers has significantly and steadily increased in the last decade. In women, the incidence of breast, colorectal, thyroid, and lung cancers has also increased significantly in the same period. Five-year survival rates for cancer of the stomach, colon, rectum, liver, lung, breast, cervix, ovary, and prostate in adults, and childhood leukemia are relatively low compared with other countries. The aim of our study was to estimate incidence and survival by means of Setif cancer registry data.

  18. Learning from defects using a comprehensive management system for incident reports in critical care.

    Science.gov (United States)

    Arabi, Y M; Al Owais, S M; Al-Attas, K; Alamry, A; AlZahrani, K; Baig, B; White, D; Deeb, A M; Al-Dozri, H D; Haddad, S; Tamim, H M; Taher, S

    2016-03-01

    Incident reporting systems are often used without a structured review process, limiting their utility to learn from defects and compromising their impact on improving the healthcare system. The objective of this study is to describe the experience of implementing a Comprehensive Management System (CMS) for incident reports in the ICU. A physician-led multidisciplinary Incident Report Committee was created to review, analyse and manage the department incident reports. New protocols, policies and procedures, and other patient safety interventions were developed as a result. Information was disseminated to staff through multiple avenues. We compared the pre- and post-intervention periods for the impact on the number of incident reports, level of harm, time needed to close reports and reporting individuals. A total of 1719 incidents were studied. ICU-related incident reports increased from 20 to 36 incidents per 1000 patient days (P=0.01). After implementing the CMS, there was an increase in reporting 'no harm' from 14.2 to 28.1 incidents per 1000 patient days (Psystem. This may be important to enhance the effectiveness of incident reporting systems in highlighting system defects, increasing learning opportunities and improving patient safety. PMID:27029653

  19. Somewhere in tertiary hospital clinical laboratory in pursuance of personnel sharp injury incidence status investigation and relative factor analysis%某地三级医院检验科采血人员锐器伤影响因素分析

    Institute of Scientific and Technical Information of China (English)

    丁娥; 李卫华; 王萍; 菅向东

    2016-01-01

    目的 调查某地三级医院检验科采血人员锐器伤发病现况及影响因素,分析其原因并探讨其控制策略.方法 选择山东省10家三级医院检验科采血人员l 198人,用横断面调查的方法,调查采血人员的职业暴露因素、组织管理因素、个人认知情况等,以x2检验及多因素Logistic回归分析方法分析数据.结果 采血工作环境中存在接触注射针头、玻璃等锐器、接触噪音、接触化学物、接触患者的血液等生物标本、接触高危人群、患者及家属负面情绪、遭受患者及家属埋怨等相关的影响因素.在组织管理因素中,以工作强度大、防护用具不足为最不满意;医务人员对职业暴露的个人认知能力因素方面,未能遵守医疗护理规范操作及发生暴露后未能及时正确处理并上报发生率较高.三级医院检验科采血人员锐器伤的发生率与岗位、超负荷工作、锐器接触、防护用具是否完善、医疗废弃物安全处置5种因素.结论 三级医院检验科采血人员锐器伤的发生率与多种因素相关,医院应制定相应的规章制度,改善工作环境,规范安全操作,以降锐器伤的发生率.%Objective Investigation in tertiary hospital clinical laboratory in pursuance of the current state of the sharp injury incidence and influencing factors,analyze the causes and discuss the control strategy.Methods Application of cross-sectional survey method,according to the unified investigation questionnaire investigation,with chi-square test and the multi-factor Logistic regression analysis methods to analyze research data.Results The work environment exit contact with injection needles,glass and other sharps,contact with noise,contact with chemicals,contact the patient's blood and other biological specimens,high-risk groups,the patient and family to negative emotions,by patients and their families complain or abuse related influencing factors.In the organization and

  20. Incidence of early pregnancy bleeding in the Eastern region of Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Wafaa Hassan

    2016-05-01

    Conclusions: The incidence of first trimester vaginal bleeding is high in our center when compared with figures from published literature. The incidence of threatened miscarriage is low, while the incidence of complete or incomplete miscarriage is relatively high. Similar to other reports from Asia, the incidence of molar pregnancy was very high. Further research is recommended to justify the detected high first trimester vaginal bleeding rates and to identify potentials of prevention or improvement of the outcomes of bleeding. [Int J Reprod Contracept Obstet Gynecol 2016; 5(5.000: 1392-1399

  1. Perceptions of the Jackson-Timberlake Super Bowl incident: role of sexism and erotophobia.

    Science.gov (United States)

    Forbes, Gordon B; Jobe, Rebecca L; White, Kay B; Richardson, Raynette M

    2005-06-01

    201 college women's and 179 men's impressions of the Jackson-Timberlake Super Bowl incident were related to measures of benevolent sexism, hostile sexism, and erotophobia. For both women and men high benevolent sexism was correlated (.17-.24) to perceptions that the incident was degrading and that agents (e.g., MTV, NFL, Hollywood) other than the actors were responsible for the incident, whereas high erotophobia was correlated (.29-.39) to perceptions that the incident was degrading, attributable to others, and personally upsetting.

  2. Safety and Health Standard 110: Incident/accident reporting and investigation

    Energy Technology Data Exchange (ETDEWEB)

    Sones, K. [West Kootenay Power, BC (Canada)

    1999-10-01

    Incident/accident reporting requirements in effect at West Kootenay Power are discussed. Details provided include definitions of low risk, high risk, and critical events, the incidents to be reported, the nature of the reports, the timelines, the investigation to be undertaken for each type of incident/accident, counselling services available to employees involved in serious incidents, and the procedures to be followed in accidents involving serious injury to non-employees. The emphasis is on the `critical five` high risk events and the procedures relating to them.

  3. Using Pareto Analysis with Trend Analysis: Statistical Techniques to Investigate Incident Reports within a Housing System

    Science.gov (United States)

    Luna, Andrew L.

    1998-01-01

    The purpose of this study was to determine trends and difficulties concerning student incident reports within the residence halls as they relate to the incident reporting system from the Department of Housing and Residential Life at a Southeastern Doctoral I Granting Institution. This study used the frequency distributions of each classified…

  4. Venous thromboembolism in ANCA-associated vasculitis - incidence and risk factors

    NARCIS (Netherlands)

    Stassen, P. M.; Derks, R. P. H.; Kallenberg, C. G. M.; Stegeman, C. A.

    2008-01-01

    Objectives. In patients with ANCA-associated vasculitis (AAV), an increased incidence of venous thromboembolism (VTE), mainly during active disease, has been described. In a large cohort of AAV patients, live assessed the incidence of VTE and its relation with disease activity and classic risk facto

  5. Analysis of the Thyroid Carcinoma Incidence in Tianjin Over a Recent Twenty-Year Period

    Institute of Scientific and Technical Information of China (English)

    Biyun Qian; Kexin Chen; Min He; Shufen Dong; Haixin Li; Fengju Song

    2005-01-01

    OBJECTIVE To analyze the incidence rate and trend of thyroid cancer in Tianjin over a recent 20-year period.METHODS A method of descriptive epidemiology was used to study the occurrence of thyroid cancer.RESULTS During 1981~2001, the average incidence rate of thyroid cancer was 1.770 per 100,000 with a male to female incidence ratio of 1:2.74, the occurrence being higher in females than in males. Thyroid cancer incidence increased gradually with time over the 20 years in both males and females, especially the incidence peaked in females of 35~50 years of age.CONCLUSION The rapid increase in the incidence rate of thyroid cancer, especially in females, suggests that further research on the risk factors and preventive efforts related to high-risk women should be conducted.

  6. Radiological terrorism and estimate leukemia incidence

    International Nuclear Information System (INIS)

    Radiological dispersal devices (RDD) are widely used as a terrorist tool leading to major environmental and public health concerns. This work is focused on simulating a dispersive scenario where an amount of most common radionuclide for this purpose is released. In order to estimate the total effective dose from such release, an affected urban area was chosen as a potential public mass concentration during World Cup in 2014 and Olympics in 2016 in Rio de Janeiro. Specialized simulation software called HotSpot Health Physics Code using a semi-empirical Gaussian model, was used to simulate dispersion of Cs-137 following detonation of a RDD. The simulation was designed to determine dose curves as a function of distance from the hot site. Additionally, it was determined the relative risk of leukemia incidence as well as statistical correlation between malignancies and exposure to radiation, based on probability of causation calculations. Results was suggestive that exists dependence on age at exposure time and the probability of leukemia development. This study emphasizes the importance of fast response, using a user-friendly computational method that may help, at first sight, to guide the response from the basic actions to the complete decision making process looking after health effects on public and environmental detriment. (author)

  7. Incidence of retrorenal colon during percutaneous nephrolithotomy

    Directory of Open Access Journals (Sweden)

    Mehmet Balasar

    2015-04-01

    Full Text Available Objective The aim of this study was to investigate retrorenal colon incidence in percutaneous nephrolithotomy (PNL interventions made in our clinic. Materials and Methods Clinical data of 804 PNL patients, accumulated over a 7 year period (2006-2012, was surveyed. The patient files were reviewed retrospectively, and only those who had abdominal computed tomography (CT images before PNL intervention were included in the study. In the CT images, the position of both the ascending and descending colon in relation to the right and left kidneys were evaluated. Results According to our hospital reports, 394 patients with CT images were included in the present study 27 patients (6.9% had retrorenal colon, of which 18 (4.6% were on the left side, 4 (1.0% on the right side and 5 (1.3% had bilateral retrorenal colons. Colonic perforation complication was seen only in two patients and the colonic perforation rate was 0.3%. These two cases had no CT images. Conclusions PNL, in the process of becoming the standard treatment modality, is a safe and reliable technique for renal stone treatment. Colonic injury should be taken into consideration during PNL interventions of the lower pole of the kidney (especially on the left side due to the location of retrorenal colon.

  8. Radiological terrorism and estimate leukemia incidence

    Energy Technology Data Exchange (ETDEWEB)

    Saint' Yves, Thalis Leon de Avila [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Instituto Nacional do Cancer (INCa), Rio de Janeiro, RJ (Brazil); Maia, Arlei; Andrade, Edson R. de [Centro Tecnologico do Exercito (CTEX), Rio de Janeiro, RJ (Brazil)

    2011-07-01

    Radiological dispersal devices (RDD) are widely used as a terrorist tool leading to major environmental and public health concerns. This work is focused on simulating a dispersive scenario where an amount of most common radionuclide for this purpose is released. In order to estimate the total effective dose from such release, an affected urban area was chosen as a potential public mass concentration during World Cup in 2014 and Olympics in 2016 in Rio de Janeiro. Specialized simulation software called HotSpot Health Physics Code using a semi-empirical Gaussian model, was used to simulate dispersion of Cs-137 following detonation of a RDD. The simulation was designed to determine dose curves as a function of distance from the hot site. Additionally, it was determined the relative risk of leukemia incidence as well as statistical correlation between malignancies and exposure to radiation, based on probability of causation calculations. Results was suggestive that exists dependence on age at exposure time and the probability of leukemia development. This study emphasizes the importance of fast response, using a user-friendly computational method that may help, at first sight, to guide the response from the basic actions to the complete decision making process looking after health effects on public and environmental detriment. (author)

  9. Effects of residential radon on cancer incidence

    International Nuclear Information System (INIS)

    Radon activity concentrations of 1077 homes were surveyed in two villages of Northern Hungary to obtain the yearly averages. The distribution of indoor radon activity concentrations covered a wide range. Cancer incidences of all the 2680 inhabitants for the last 30 years were also studied in these villages in order to establish a possible correlation with radon exposure. The methods applied in the analysis allow to draw up statistically supported statements concerning the relative cancer risks of different radon level groups. The results show that among non-smoking middle-aged women the frequency of cancer, regardless to tumor types, is lower for those who live in residential radon activity concentrations of a level between 110 and 185 Bq x m-3 compared to those living in radon levels outside this range. A minimum value in the cancer frequency exists at a level of significance p<0.008 (determined with the help of Fisher's test). In general, the present study corroborates the outcome of other studies demonstrating the existence of a biopositive effect, and suggests a wider concept of radon health effects. (author)

  10. Incidence of ascariasis in gastric carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jong Woo; Rhee, Hak Song; Bahk, Yong Whee [St Mary' s Hospital Catholic Medical College, Seoul (Korea, Republic of)

    1972-09-15

    Prompted by the finding that the radiological incidence of small bowel ascariasis in the patient with gastric carcinoma was unexpectedly lower than the incidence in the normal population, a clinical study was performed to investigate possible relationship between gastric carcinoma and intestinal ascariasis. As a preliminary survey, we reviewed the radiological incidence of ascariasis in a total of 2,446 cases of upper GI series performed at the Department of Radiology, St Mary's Hospital Catholic Medical College. These included 1,573 normal subjects, 146 gastric carcinoma patients, 100 benign gastric ulcer and 249 duodenal ulcer patients and 378 other upper GI diseases. Following the preliminary study, a more accurate parasitologic study was conducted in another 578 normal subjects and 51 gastric carcinoma patients. The radiological incidences of ascaiasis in normal subjects and gastric carcinoma patients were 15.1% and 28.1%, respectively. The incidence of overall helminthiasis including ascaris lumbricoides, trichocephalus trichiurus and trichostrongyloides orientalis in normal subjects of the present series was 73.5%. This figure is virtually the same with 69.1% of the general population incidence reported by Kim, et al. (1971), but the incidence in gastric carcinoma patients was 94.1%. The high incidence pattern of overall helminthiasis in gastric carcinoma patients is, however, reversed as for as ascariasis is concerned. Thus, the incidence of ascariasis of gastric carcinoma patients was much lower than that of normal subjects (9.8% vs 19.4%). From the present observation, it is postulated that there can be some possible antagonistic relationship between evolution of gastric carcinoma and small bowel infestation of ascaris lumbricoides.

  11. Diffraction of H from LiF(001): From slow normal incidence to fast grazing incidence

    Science.gov (United States)

    Muzas, A. S.; Gatti, F.; Martín, F.; Díaz, C.

    2016-09-01

    Describing diffraction of atomic and molecular projectiles at fast grazing incidence presents a real challenge for quantum theoretical simulations due to the high incidence energy (100 eV-1 keV) used in experiments. This is one of the main reasons why most theoretical simulations performed to date are based on reduced dimensional models. Here we analyze two alternatives to reduce the computational effort, while preserving the real dimensionality of the system. First, we show that grazing incidence conditions are already fulfilled for incidence angles ⩽ 5 ° , i.e., incidence angles higher than those typically used in experiments. Thus, accurate comparisons with experiment can be performed considering diffraction at grazing incidence, but with smaller total incidence energies, whilst keeping the same experimental normal energy in the calculations. Second, we show that diffraction probabilities obtained at fast grazing incidence are fairly well reproduced by simulations performed at slow normal incidence. This latter approach would allow one to simulate several experimental spectra, measured at the same normal incidence energy for several incidence crystallographic directions, with only one calculation. This approach requires to keep the full dimensionality of the system.

  12. Incidence and Mortality of Spontaneous Subarachnoid Hemorrhage in Martinique.

    Directory of Open Access Journals (Sweden)

    Mathieu Schertz

    Full Text Available Incidence of spontaneous subarachnoid hemorrhages (SAH varies wildly across the world and seems to be low in Central and South America (4.2 per 100 000 person-years; CI 95%; 3.1-5.7. The objective of our study was to describe the characteristics of SAH and to estimate its incidence and severity in Martinique, a small French island located in the Caribbean Sea.Due to its insular nature and small captive population, Martinique is ideal for the setting up of population-based epidemiological studies with good exhaustiveness. Our study, spanning a 7 year period (2007-2013, consisted of retrospective case ascertainment with multiple overlapping methods. Crude incidence and 30 day case-fatality rates for SAH among the Martinican population were computed for the study period. Incidence and disease severity was also analyzed according to age, gender and aneurysm presence. World age-standardized incidence rates were also calculated.A total of 121 patients had a SAH during the study period, with a higher frequency of female cases (71.1% versus 28.9%, p<0.001. Patient mean age was 57.1 years (median = 55 [46-66]. An aneurysmal origin was found in 96 SAH cases (79.3%. Crude annual incidence was 4.36 per 100 000 person-years (CI 95% 2.30-6.42. World age-standardized incidence was 3.29 per 100 000 person-years (CI 95% 1.74-4.84. During the 30 days following SAH diagnosis, 29 patients died (case fatality rate: 24% (CI 95% 16.4-31.6.The incidence of spontaneous subarachnoid hemorrhage in Martinique is much lower than in other parts of the world and similar to countries in Central and South America. These results are possibly related to environmental factors and most particularly to a low rate of smoking in the Martinican population. Thirty-day case-fatality rate is similar to what is observed in developed countries.

  13. IAEA Inspector Involved in Contamination Incident

    International Nuclear Information System (INIS)

    Full Text: An IAEA safeguards inspector was involved in a contamination incident yesterday afternoon at the Belgoprocess nuclear waste processing facility in Dessel, Belgium. The inspector, accompanied by a EURATOM inspector and a Belgoprocess official, was conducting a routine inspection at the facility when the incident occurred. The three individuals evacuated the area and have undergone external decontamination procedures and medical checks. They are now being assessed to determine the level of their radiation exposure. Belgian authorities have reported that the incident area has been sealed off and no radioactivity has been released to the environment. Decontamination of the facility is expected to begin soon. The IAEA's Incident and Emergency Centre (IEC) is in contact with Belgian officials to collect information about the exposure to radiation, the nuclear material involved and other details. (IAEA)

  14. Social monitoring research for predicting mass incidents

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ Based on surveys of resident attitude, a social monitoring research team with the CAS Institute of Psychology has established a predicting model on the possibility of mass incidents, that is, collective conflicts against the administration.

  15. Incidence of tuberculosis in and around Banglore

    Directory of Open Access Journals (Sweden)

    K. L. Phaniraja

    2010-08-01

    Full Text Available Incidence of Tuberculosis is higher in developing countries due to absence of National control and Eradication programme. Incidence is higher due to close contact with infected animal or human being. In the present study, 2668 bovines were screened for tuberculosis by single intradermal test from 15 different organized government and private farm. Currently, the SID test is used worldwide to determine whether an animal is sensitized to Mycobacterial antigens or not and the test is approved by OIE. Out of which, incidence of 2.89% in HF cross breeds, 0.69% in Jersey cross bred animals and none were shown reactor to Single Intradermal test in Indigenous animals. The higher incidence of 3.26% was found in female and 0.48% found in male. The calves which were below two year of age were found 1.56% reactor. [Vet World 2010; 3(4.000: 161-164

  16. Oil Spill Incident Tracking [ds394

    Data.gov (United States)

    California Department of Resources — The Office of Spill Prevention and Response (OSPR) Incident Tracking Database is a statewide oil spill tracking information system. The data are collected by OSPR...

  17. Malignant mesothelioma: global incidence and relationship with asbestos.

    Science.gov (United States)

    Bianchi, Claudio; Bianchi, Tommaso

    2007-06-01

    Mesothelioma incidence varies markedly from one country to another. The highest annual crude incidence rates (about 30 cases per million) are observed in Australia, Belgium, and Great Britain. A lot of data indicate a relationship between mesothelioma and asbestos. The hot areas for mesothelioma exactly correspond to the sites of industries with high asbestos use, such as shipbuilding and asbestos-cement industry. However, in many countries with high asbestos consumption, mesothelioma incidence is low. The reasons for this fact are not clear. The latency periods elapsing between first exposure to asbestos and development of mesothelioma are mostly longer than 40 yr. An inverse relationship exists between intensity of asbestos exposure and length of the latency period. Mesothelioma generally develops after long-time exposures to asbestos. Some recent studies show that the risk increases with the duration of exposure. Possible co-factors in the pathogenesis of asbestos-related mesothelioma include genetic predisposition, diets poor in fruit and vegetables, viruses, immune impairment, recurrent serosal inflammation. The study of co-morbidity in mesothelioma could give an insight into the pathogenesis of the tumor. While a levelling-off in mesothelioma incidence has been registered in some countries, a worsening of the epidemic is predictable in large parts of the world. PMID:17634686

  18. INCIDENCE OF NEONATAL HYPERBILIRUBINEMEA IN TERM NEW BORNS AT KBNTGH

    OpenAIRE

    Mujumdar; Siddaling; Preethi; Nabeel; Harshavardhan

    2015-01-01

    AIM AND SCOPE: We conducted this study to estimate the incidence of hyperbilirubinemia in term new born with birth weight >2.5 kgs born at neonatal care unit of KBNTGH, and to determine the underlying causes, which would be of value in identifying and implementing strategies to prevent morbidity from this condition. BACKGROUND: Management of hyperbilirubinemia remains a challenge for neonatal medicine because of the risk for serious neurological complications related to the to...

  19. How effective incident management retains market share.

    Science.gov (United States)

    Enright, Courtenay

    2012-01-01

    This paper discusses the need for business continuity practitioners to make incident management a focal element of their programme. Particularly during the first few minutes and hours of a business disruption, an established incident management methodology is not only key to achieving a successful, coordinated recovery, but it can play an even more important role in maintaining customer confidence following a disruption or crisis. PMID:22948102

  20. Cancer-specific incidence rates of tuberculosis

    Science.gov (United States)

    Seo, Gi Hyeon; Kim, Min Jae; Seo, Soyoung; Hwang, Boram; Lee, Eugene; Yun, Yujin; Choi, Minsun; Kim, Moonsuk; Kim, Jin Won; Kim, Eu Suk; Kim, Hong Bin; Song, Kyoung-Ho

    2016-01-01

    Abstract Population-based studies of the incidence of tuberculosis in cancer patients according to the type of cancer are limited. We investigated the cancer-specific incidence of tuberculosis in a nationwide population-based cohort in a country with an intermediate burden of tuberculosis. We used mandatory National Health Insurance claims data to construct a cancer cohort of adults (aged 20–99 years) with newly diagnosed malignancies other than lung cancer, from January 2008 to December 2012. Patients who developed tuberculosis in this period were identified in the cancer cohort and the general population. Standardized incidence ratios (SIRs) of tuberculosis in the cancer cohort according to type of cancer and time after cancer diagnosis were calculated by comparing the observed incidence rates with those inferred from the age- and gender-specific incidence rates in the general population. A total of 855,382 cancer patients and 1589,876 person-years (py) were observed. A total of 5745 patients developed tuberculosis; the mean incidence rate was 361.3 per 100,000 py, and the SIR was 2.22 (95% confidence interval [CI], 2.17–2.27). The incidence rate was highest for hematologic malignancy and lowest for thyroid cancer. It was also highest as 650.1 per 100,000 py, with SIR of 3.70 (CI, 3.57–3.83) for the first 6 months after diagnosis of malignancy and then declined. However, it still remained higher than that of the general population after 24 months (SIR = 1.43, CI, 1.36–1.51). The incidence of tuberculosis increases after diagnosis in patients with malignancies. The risk of tuberculosis differs according to the type of cancer and remains elevated even 24 months after cancer diagnosis. Tuberculosis should be considered an important comorbidity in patients with malignancies. PMID:27661041

  1. State methods for a cyber incident

    OpenAIRE

    Mulligan, Michael R.

    2012-01-01

    Approved for public release; distribution is unlimited The National Cyber Incident Response Plan stipulates the state homeland security advisor as the contact point for a significant cyber incident. But this may not be the most effective method of response because the state homeland security advisors are not domain experts for cyberspace. A questionnaire was sent to state chief information officers and/or state chief information security officers to determine current capability an...

  2. Simultaneity of Crime Incidence in Mindanao

    OpenAIRE

    Madanlo, Lalaine; Murcia, John Vianne; Tamayo, Adrian

    2016-01-01

    The study simulated the predictive relationships of regional monthly crime rates for a period covering January 2009 to July 2013. A six-equation model representing the six regions in Mindanao was estimated using the seemingly unrelated regression (SUR). The SUR estimation shows that the increase of incidences of crimes in Southern Mindanao Region and SOCCSKSARGEN tended a 1.73% rise and 0.85% reduction in crime incidences in Zamboanga Peninsula. Monthly crime rates in Northern Mindanao in...

  3. Lunar Tractive Forces and Renal Stone Incidence

    OpenAIRE

    Spyridon Arampatzis; Thalmann, George N.; Heinz Zimmermann; Exadaktylos, Aristomenis K

    2011-01-01

    Background. Several factors are implicated in renal stone formation and peak incidence of renal colic admissions to emergency departments (ED). Little is known about the influence of potential environmental triggers such as lunar gravitational forces. We conducted a retrospective study to test the hypothesis that the incidence of symptomatic renal colics increases at the time of the full and new moon because of increased lunar gravitational forces. Methods. We analysed 1500 patients who atten...

  4. Congenital hypothyroidism: increased incidence in Asian families.

    OpenAIRE

    Rosenthal, M; Addison, G. M.; Price, D. A.

    1988-01-01

    Screening in the North West health region of England showed a significantly higher incidence of congenital hypothyroidism in Asian families--1/918 compared with 1/3391 in non-Asians. This could only in part be explained by consanguinity. No differences were found in birth order, season of birth, gestational age, or birth weight between normal infants and those with congenital hypothyroidism. There was a significantly higher incidence of additional congenital abnormalities (9%) and a significa...

  5. Creative accounting: Nature, incidence and ethical issues

    OpenAIRE

    Amat, Oriol; Gowthorpe, Catherine

    2004-01-01

    This paper explores the nature and incidence of creative accounting practices within the context of ethical considerations.It explores several definitions of creative accounting and the potential and the range of reasons for a company's directors to engage in creative accounting. Later the paper considers the various ways in which creative accounting can be undertaken and summarizes some empirical research on the nature and incidence of creative accounting. The ethical dimen...

  6. INCIDENCE AND RELATED FACTORS OF PTSD IN RESCUE OFFICERS AND SOLDIERS 2 YEARS AFTER WENCHUAN EARTHQUAKE%汶川地震后2年救灾官兵创伤后应激障碍的发生率及其影响因素

    Institute of Scientific and Technical Information of China (English)

    石文磊; 刘宇凝; 沈兴华

    2012-01-01

    Objective To examine the incidence and related factors of posttraumatic stress disorder (PTSD) in rescue officers/soldiers 2 years after earthquake, thus to provide a theoretical basis for prevention and reduction of PTSD incidence among rescuers after earthquake. Methods PTSD Checklist Military Version (PCL-M) ,Self-Rating Depression Scale (SDS),State Anxiety Inventory (SAI) test,Simplified Coping Style Questionnaire (SCSQ),and General Questionnaire, as well as cluster sampling were adopted to investigate 144 rescue officers/soldiers after Wenchuan earthquake (the rescue group) and another 95 officers/soldiers who did not attend the rescue mission (the control group) but from the same troop.Results (1 )The incidence of PTSD in rescue group (16.7%) was significantly higher than in control group (1.0% ) , ( P < 0.01) . (2)The factor scores and total score of 17 items in PLC-M, and total score of three symptoms in military rescuers were significantly higher than in the control( P < 0.01) . (3)Multiple regression analysis showed that the main risk factors of PTSD were too much negative coping style,excessive worry about health,having more trouble after rescue mission, feeling of less friends and other support, feeling of emotional instability ordinarily, and feeling of effort-reward imbalance after rescue mission. Conclusion After 2 years of earthquake, the incidence of PTSD in rescue group was higher than in control group. And personal coping style,support from friends and society,personal emotion,and the living circumstance happened after rescue are the related factors.%目的 了解汶川地震后2年参加救灾官兵心理创伤后应激障碍(PTSD)的发生率及其影响因素,为救灾后官兵心理防护提供依据,并为减少救灾官兵PTSD发生率提供措施.方法 应用军事应激障碍核查表(PCL-M)、抑郁自评量表(SDS)、状态焦虑量表(SAI)、简易应对方式问卷(SCSQ)、领悟社会支持量表(PSSS)及一

  7. Incident Reporting in Mashhad Hospitals

    Directory of Open Access Journals (Sweden)

    Davoodi R

    2013-10-01

    Full Text Available Objectives: In this study, our aim was to evaluate and classify the voluntary error reports in the hospitals of Mashhad University of Medical Sciences. Patients have the right to receive health care in accordance to the best standards. Health care carries a risk of harm for patient safety, and with respect to today’s stressful systems with a large number of patients, it would be inevitable. The meaning of risk management is to predict adverse events and reduce their occurrence.Materials and Methods: A voluntary medical error reporting form was designed and approved by the clinical governance team of Mashhad Medical University. They were then distributed inside hospitals in the way in which everyone (health providers and patients could access them easily. The forms were collected and classified monthly in all wards. Classification was performed on the base of type, outcome and reporter. Data gathering took place from spring to autumn 2012. The data was analyzed by the SPSS software. Results: 2500 errors were extracted from 1000 voluntary error reporting forms of the 12 hospitals of Mashhad Medical University. The most frequent error type was treatment errors (36% related to drug administration, standard procedures and surgical events. Conclusions: Error reporting as a basic activity has an important role in discovering pitfalls of the health care system. To promote the reporting culture, its non punitive base must become clear for all professors and staff members, because this kind of reporting could lead to fewer medical errors and higher staff awareness about probable errors.

  8. 老年男性保健人群六年累计缺血性心血管病发病率及其危险因素的前瞻性研究%A prospective study on 6-year accumulative incidence rate of ischemic cardiovascular disease and related risk factors among the elderly male population under health care programme

    Institute of Scientific and Technical Information of China (English)

    陈金宏; 吴海云; 何昆仑; 何耀; 秦银河

    2010-01-01

    目的 研究老年保健人群6年累计缺血性心血管病(ICVD)的发病率及其相关危险因素.方法 基线人群为2003年5月某医院数据库记录在案的、出生于1938年1月1日前(即年龄>65岁)的所有老年保健对象,剔除基线时已患有ICVD者.收集的危险因素有:基线时年龄、性别、体重指数、收缩压、血总胆固醇浓度、血甘油三酯浓度、血高密度脂蛋白胆固醇(HDL-C)浓度、血肌酐浓度、血载脂蛋白A1浓度、糖尿病、吸烟,以人年作为观察时间,计算基线危险因素不同分期水平下的人年发病率及累计发病率,进行单因素分析.使用Cox比例风险回归模型进行多因素分析.结果 基线人群为2271名男性老年人,6年内ICVD累计发病率为23.56%,人年发病率达到了45.41‰.单因素分析表明,与ICVD事件正相关的变量是:收缩压、体重指数、血总胆固醇水平、血甘油三酯水平、血载脂蛋白A1水平、糖尿病、吸烟;与ICVD事件负相关的变量是:血HDL-C浓度、血肌酐浓度;多元Cox比例风险模型的分析结果显示:收缩压、糖尿病、血总胆固醇、体重指数是最主要的危险因素,血HDL-C是主要的保护因素.结论 老年保健人群ICVD发病率较高.控制血压、血糖,提高血HDL-C水平可能是降低未来ICVD事件最为有效的措施.%Objective To investigate the 6-year accumulative incidence rate of ischemic cardiovascular disease (ICVD) and its related risk factors. Methods Baseline population was all from an elderly population with members all born before 1-1,1938 and under health care programm.Data was recorded in a database of a hospital and baseline of subjects under research was aged >65years. People that had had ICVD at baseline were excluded. Risk factors under research would include: age at the baseline study, gender, body mass index, systolic blood pressure, serum cholesterol level, serum triglyceride level, serum high-density lipoprotein

  9. Emergency Incident Rehabilitation: Resource Document to the Position Statement of the National Association of EMS Physicians.

    Science.gov (United States)

    Hostler, David; McEntire, Serina J; Rittenberger, Jon C

    2016-01-01

    Position Statement: Emergency Incident Rehabilitation The National Association of EMS Physicians® believes that: Emergency operations and training conducted while wearing protective clothing and respirators is physiologically and cognitively demanding. The heat stress and fatigue created by working in protective clothing and respirators creates additional risk of illness/injury for the public safety provider. Emergency incident rehabilitation provides a structured rest period for rehydration and correction of abnormal body core temperature following work in protective clothing and respirators. Emergency incident rehab should be conducted at incidents (e.g. fireground, hazardous materials, and heavy rescue emergencies) and trainings involving activities that may lead to exceeding safe levels of physical and mental exertion. Emergency incident rehabilitation is incident care, not fitness for duty, and meant to reduce physiologic strain and prepare the responder to return to duty at the current incident and for the remainder of the shift. EMS should play a role in emergency incident rehabilitation with providers trained to understand the physiologic response of healthy individuals to environmental, exertional, and cognitive stress and implement appropriate mitigation strategies. An appropriately qualified physician should have oversight over the creation and implementation of emergency incident rehabilitation protocols and may be separate from the roles and responsibilities of the occupational medicine physician. There are no peer-reviewed data related to cold weather rehabilitation. Future studies should address this limitation to the literature. PMID:26847801

  10. Quality review of an adverse incident reporting system and root cause analysis of serious adverse surgical incidents in a teaching hospital of Scotland

    Directory of Open Access Journals (Sweden)

    Khorsandi Maziar

    2012-08-01

    Full Text Available Abstract Background A significant proportion of surgical patients are unintentionally harmed during their hospital stay. Root Cause Analysis (RCA aims to determine the aetiology of adverse incidents that lead to patient harm and produce a series of recommendations, which would minimise the risk of recurrence of similar events, if appropriately applied to clinical practice. A review of the quality of the adverse incident reporting system and the RCA of serious adverse incidents at the Department of Surgery of Ninewells hospital, in Dundee, United Kingdom was performed. Methods The Adverse Incident Management (AIM database of the Department of Surgery of Ninewells Hospital was retrospectively reviewed. Details of all serious (red, sentinel incidents recorded between May 2004 and December 2009, including the RCA reports and outcomes, where applicable, were reviewed. Additional related information was gathered by interviewing the involved members of staff. Results The total number of reported surgical incidents was 3142, of which 81 (2.58% cases had been reported as red or sentinel. 19 of the 81 incidents (23.4% had been inappropriately reported as red. In 31 reports (38.2% vital information with regards to the details of the adverse incidents had not been recorded. In 12 cases (14.8% the description of incidents was of poor quality. RCA was performed for 47 cases (58% and only 12 cases (15% received recommendations aiming to improve clinical practice. Conclusion The results of our study demonstrate the need for improvement in the quality of incident reporting. There are enormous benefits to be gained by this time and resource consuming process, however appropriate staff training on the use of this system is a pre-requisite. Furthermore, sufficient support and resources are required for the implementation of RCA recommendations in clinical practice.

  11. Is there an effect of glucose lowering treatment on incidence and prognosis of tuberculosis?

    DEFF Research Database (Denmark)

    Jørgensen, Marit Eika; Faurholt-Jepsen, Daniel

    2014-01-01

    The association between diabetes and incidence of tuberculosis is well established, and observational studies have shown poor treatment outcome in tuberculosis related to hyperglycemia. The WHO recommends screening for diabetes among all patients with tuberculosis and optimized glycemic control...

  12. Incidence of venous thromboembolism in oral and maxillofacial surgery: a retrospective analysis

    NARCIS (Netherlands)

    T. Forouzanfar; M.W. Heymans; A. van Schuilenburg; S. Zweegman; E.A.J.M. Schulten

    2010-01-01

    This study retrospectively investigates the incidence and risk factors for venous thromboembolism (VTE) in patients undergoing maxillofacial surgery. Data were obtained from patients treated between January 2005 and June 2006. Patients’ records were reviewed for complaints and information relating t

  13. Trends in head and neck cancer incidence in Denmark, 1978-2007: Focus on human papillomavirus associated sites

    DEFF Research Database (Denmark)

    Blomberg, Maria; Nielsen, Ann; Plum, Christian Edinger Munk;

    2011-01-01

    and the overall incidence increased throughout the period. Significantly increasing incidence rates were notably seen for tumors in the oral cavity (2.2% per year), tonsils (4.8% per year), oropharynx (3.5% per year) and hypopharynx (4.4% per year). A significantly decreasing incidence of lip cancer was observed...... among men (-5.0% per year). Cancers at HPV-associated sites (n = 3650) showed strongly increasing incidence rates, primarily in individuals years. In contrast, HNCs at sites not related to HPV infection showed a significant decrease (in men) or virtually no change in incidence (in women). Our...

  14. Incidence and epidemiology of tibial shaft fractures

    DEFF Research Database (Denmark)

    Larsen, Peter; Elsøe, Rasmus; Hansen, Sandra Hope;

    2015-01-01

    Introduction: The literature lacks recent population-based epidemiology studies of the incidence, trauma mechanism and fracture classification of tibial shaft fractures. The purpose of this study was to provide up-to-date information on the incidence of tibial shaft fractures in a large and compl......Introduction: The literature lacks recent population-based epidemiology studies of the incidence, trauma mechanism and fracture classification of tibial shaft fractures. The purpose of this study was to provide up-to-date information on the incidence of tibial shaft fractures in a large...... the highest frequency between the age of 30 and 40. AO-type 42-A1 was the most common fracture type, representing 34% of all tibial shaft fractures. The majority of tibial shaft fractures occur during walking, indoor activity and sports. The distribution among genders shows that males present a higher...... frequency of fractures while participating in sports activities and walking. Women present the highest frequency of fractures while walking and during indoor activities. Conclusion: This study shows an incidence of 16.9/100,000/year for tibial shaft fractures. AO-type 42-A1 was the most common fracture type...

  15. Early childhood leukemia incidence trends in Brazil.

    Science.gov (United States)

    Reis, Rejane de Souza; Santos, Marceli de Oliveira; de Camargo, Beatriz; Oliveira, Julio Fernando Pinto; Thuler, Luiz Claudio Santos; Pombo-de-Oliveira, Maria S

    2016-03-01

    Incidence rates of childhood leukemia vary between different regions of the world. The objective of this study was to test possible trends in incidence rate of early childhood leukemia (children leukemia was 61 per million. The AAIR for acute lymphoid leukemia (ALL) was 44 per million and nonlymphoid acute leukemia (NLAL) was 14 per million. The median ALL/NLAL ratio was 3.0, suggesting higher incidence rate of NLAL in these settings. The joinpoint analysis demonstrated increased leukemia incidence rate in João Pessoa (AAPC = 20; 95% CI: 3.5, 39.4) and Salvador (AAPC = 8.68; 95% CI: 1.0, 16.9), respectively, whereas incidence rate in São Paulo PBCR decreased (AAPC = -4.02%; 95% CI: -6.1%, -1.9%). Correlation between ALL AAIR and selected variables of socioeconomic (SES) factors was not observed. Increased AAIR regionally overtime was observed. However, the interpretation for such phenomenon should be cautious because it might reflect the access to health care, diagnosis procedures, and improvement of PBCR´s quality. The observed trend supports the necessity of further ecological studies. PMID:26925506

  16. Incidence and overall survival of malignant ameloblastoma.

    Directory of Open Access Journals (Sweden)

    Alexandra Rizzitelli

    Full Text Available Malignant ameloblastoma, comprising metastasizing ameloblastoma and ameloblastic carcinoma, represents 1.6-2.2% of all odontogenic tumors. Due to its rare nature, malignant ameloblastoma has only been reported in the literature in small case series or case reports. Using the Surveillance, Epidemiology and End-Results (SEER database, we have performed a population-based study to determine the incidence rate and the absolute survival of malignant ameloblastoma.Using the International Classification of Diseases for Oncology (ICD-O codes 9310/3 and 9270/3, data from the SEER database were used to calculate the incidence rate and absolute survival rate of population with malignant ameloblastoma.The overall incidence rate of malignant ameloblastoma was 1.79 per 10 million person/year. The incidence rate was higher in males than females and also higher in black versus white population. The median overall survival was 17.6 years from the time of diagnosis and increasing age was associated with a statistically significant poorer survival.To our best knowledge, we report the largest population-based series of malignant ameloblastoma. The incidence rate was 1.79 per 10 million person/year and the overall survival was 17.6 years.

  17. Pilot Critical Incident Reports as a Means to Identify Human Factors of Remotely Piloted Aircraft

    Science.gov (United States)

    Hobbs, Alan; Cardoza, Colleen; Null, Cynthia

    2016-01-01

    It has been estimated that aviation accidents are typically preceded by numerous minor incidents arising from the same causal factors that ultimately produced the accident. Accident databases provide in-depth information on a relatively small number of occurrences, however incident databases have the potential to provide insights into the human factors of Remotely Piloted Aircraft System (RPAS) operations based on a larger volume of less-detailed reports. Currently, there is a lack of incident data dealing with the human factors of unmanned aircraft systems. An exploratory study is being conducted to examine the feasibility of collecting voluntary critical incident reports from RPAS pilots. Twenty-three experienced RPAS pilots volunteered to participate in focus groups in which they described critical incidents from their own experience. Participants were asked to recall (1) incidents that revealed a system flaw, or (2) highlighted a case where the human operator contributed to system resilience or mission success. Participants were asked to only report incidents that could be included in a public document. During each focus group session, a note taker produced a de-identified written record of the incident narratives. At the end of the session, participants reviewed each written incident report, and made edits and corrections as necessary. The incidents were later analyzed to identify contributing factors, with a focus on design issues that either hindered or assisted the pilot during the events. A total of 90 incidents were reported. Human factor issues included the impact of reduced sensory cues, traffic separation in the absence of an out-the-window view, control latencies, vigilance during monotonous and ultra-long endurance flights, control station design considerations, transfer of control between control stations, the management of lost link procedures, and decision-making during emergencies. Pilots participated willingly and enthusiastically in the study

  18. Uveitis in juvenile chronic arthritis: incidence, clinical features and prognosis.

    Science.gov (United States)

    Kanski, J J

    1988-01-01

    Three hundred and fifteen patients with anterior uveitis and juvenile chronic arthritis were reviewed in order to determine the incidence, visual prognosis, and the clinical characteristics of the intraocular inflammation. The overall incidence of uveitis was 20%. Approximately 25% of patients had relatively mild and/or transient involvement and an excellent visual prognosis. In 50% the uveitis was more severe but could be controlled with topical medication. In the remaining 25% the visual prognosis was poor due to the intractable nature of the uveitis and the subsequent development of vision-threatening complications. The majority of patients (74%) were under the age of 8 years when the uveitis was first diagnosed. Clinically, the intraocular inflammation was most frequently an asymptomatic, chronic, non-granulomatous, iridocyclitis which was bilateral in 71% of cases. Other ocular lesions, which were rare, included keratoconjunctivitis sicca and corneal melting.

  19. Benchmark analysis for quantifying urban vulnerability to terrorist incidents.

    Science.gov (United States)

    Piegorsch, Walter W; Cutter, Susan L; Hardisty, Frank

    2007-12-01

    We describe a quantitative methodology to characterize the vulnerability of U.S. urban centers to terrorist attack, using a place-based vulnerability index and a database of terrorist incidents and related human casualties. Via generalized linear statistical models, we study the relationships between vulnerability and terrorist events, and find that our place-based vulnerability metric significantly describes both terrorist incidence and occurrence of human casualties from terrorist events in these urban centers. We also introduce benchmark analytic technologies from applications in toxicological risk assessment to this social risk/vulnerability paradigm, and use these to distinguish levels of high and low urban vulnerability to terrorism. It is seen that the benchmark approach translates quite flexibly from its biological roots to this social scientific archetype.

  20. Hepatitis B prevalence and incidence in Greenland

    DEFF Research Database (Denmark)

    Børresen, Malene Landbo; Andersson, Mikael; Wohlfahrt, Jan;

    2015-01-01

    Greenland remains a highly endemic area for hepatitis B virus (HBV) infection. This is in sharp contrast to other modern societies, such as Denmark. To address this discrepancy, we investigated the natural history of HBV infection in Greenland by estimating the age-specific incidence of HBV...... infection, the proportion of chronic carriers, and the rates of hepatitis B surface antigen seroclearance. In total, 8,879 Greenlanders (16% of the population) from population-based surveys conducted in 1987 and 1998 were followed through March 2010. Data on HBV status were supplemented by HBV test results...... from all available HBV registries in Greenland to determine changes in HBV status over time. Incidence rates of HBV infection and hepatitis B surface antigen seroclearance were estimated after taking into account interval censoring. The incidence of HBV infection in 5-14-year-old subjects was less than...

  1. Incidence and prevalence of epilepsy in Denmark

    DEFF Research Database (Denmark)

    Christensen, Jakob; Vestergaard, Mogens; Pedersen, Marianne G;

    2007-01-01

    PURPOSE: To estimate the occurrence of epilepsy in Denmark between 1977 and 2002, taking gender, age, and secular trends into consideration. METHODS: We used the Danish Civil Registration System to identify all persons born in Denmark and the Danish National Hospital Register to identify persons...... registered with epilepsy between 1977 and 2002. RESULTS: Between 1977 and 2002 the average incidence of epilepsy was 68.8 new epilepsy patients per 100,000 person-years at risk. However, the incidence changed with calendar time and increased steeply from 1990 to 1995, probably due to changes in diagnostic...... declined from a high level in children to a low level between 20 and 40 years of age, and thereafter a gradual increase was seen. The incidence rate was slightly higher in men than in women except for the age range 10-20 years. About 2% of the population was diagnosed with epilepsy at some point during...

  2. Psychological impact of the Three Mile Island incident

    International Nuclear Information System (INIS)

    This study examines the psychological impact of the Three Mile Island incident. The results are based on data from a panel study of 403 persons living within five miles of Three Mile Island (TMI), and a telephone survey of 1,506 people living within 55 miles of that area. Active coping strategies were associated with continued high levels of distress. Having more friends was related to reduced distress, but introspection, taking protective actions, being active in organizations, and seeking out others were all related to higher levels of distress. High self-esteem was related to a decrease in symptoms and psychotropic drug use, and avoidance behaviors were related to higher than expected numbers of symptoms. Efforts to profile those who used different coping strategies were relatively unsuccessful. The results emphasize the need to consider the nature of the stressor when developing models of coping and response to stressful situations

  3. 肥胖相关基因多态性对儿童期肥胖发生风险及持续状态的影响%Risk of obesity-related gene polymorphism on the incidence and durative of childhood obesity

    Institute of Scientific and Technical Information of China (English)

    赵小元; 张美仙; 程红; 闫银坤; 吴丽君; 沈玥; 米杰

    2013-01-01

    病的影响不可忽视.%Objective To examine the impact of single nucleotide polymorphisms (SNPs) in obesity-related genes on the incidence and durative of obesity in childhood and adolescence.Methods Based on the Beijing Child and Adolescent Metabolic Syndrome (BCAMS) Study,780 school children aged 6 to 16 years were followed-up in 2010,and assessed for body size parameters.Venipuncture blood samples were collected after a 12-hour overnight fast.Genomic DNA was isolated from peripheral blood white cells under the salt fractionation method.SNPs were genotyped by ABI 5700 real time PCR (FTO rs9939609) and TaqMan Allelic Discrimination Assays with the GeneAmp 7900 Sequence Detection System (Applied Biosystems,Foster City,CA,USA) (FTO rs6499640,FAIM2 rs7138803,NPC1 rs1805081,MC4R rs17782313,BDNF rs6265,GNPDA2 rs10938397).Both overweight and obesity were diagnosed by the Chinese age-and sex-specific body mass index (BMI)cutoffs.Two independent sample t-test,Chi-square test and multiple logistic regression analysis were performed.Results During the 6 years follow-up period,the incidence of obesity in the total sample 8.5%,and 65.1% individuals had persisted their obese status.The genotypes of the SNPs except BDNF rs6265 were in Hardy-Weinberg equilibrium in each group (P>0.05).The incidence rates of obesity increased with FTO rs9939609 TT,TA and AA genotypes (x2 for trend=8.030,P<0.05).In the non-obese sub-cohort,after adjusted for sex,age at the initial time of follow up and residential area,when compared with children carrying FTO rs9939609 T-allele,a significantly relative risk of obesity was observed for children carrying the rs9939609 A-allele (OR=2.42,95%CI:1.31-4.47,P=0.005).In the obese sub-cohort,FTO rs9939609 A-allele was significantly associated with durative of obesity (OR=1.72,95%CI:1.07-2.77,P=0.026).However,no statistical significant associations were seen between other SNPs (FTO rs6499640,FAIM2 rs7138803,NPCI rs1805081,MC4R rs17782313,GNPDA2 rs10938397) and the incidence or

  4. Air pollutants and incidence of respiratory disease

    Energy Technology Data Exchange (ETDEWEB)

    Dohan, F.C.

    1961-01-01

    The correlation of prolonged (> 7 days) respiratory disease incidence in women working in electronics plants was studied with various pollutant indices. A three-year study of plants in 7 cities was conducted. Mean incidence was significantly correlated with suspended particulate sulfate (r = 0.964, 5 cities). No similar trend was found for benzene-soluble organic matter (OM), acetone-soluble OM, nitrates, Cu, Ti, Bi, Cd, Fe, Pb, Sn, Cl, or Zn. Similar trends for Ni and V, however, were noted. Various factors (e.g., age, socio-economic class, children, weather) were not thought to affect this conclusion. Pollution may prolong illness due to viral disease.

  5. Learning from adverse incidents involving medical devices.

    Science.gov (United States)

    Amoore, John; Ingram, Paula

    While an adverse event involving a medical device is often ascribed to either user error or device failure, the causes are typically multifactorial. A number of incidents involving medical devices are explored using this approach to investigate the various causes of the incident and the protective barriers that minimised or prevented adverse consequences. User factors, including mistakes, omissions and lack of training, conspired with background factors--device controls and device design, storage conditions, hidden device damage and physical layout of equipment when in use--to cause the adverse events. Protective barriers that prevented or minimised the consequences included staff vigilance, operating procedures and alarms. PMID:12715578

  6. Rising incidence of Merkel cell carcinoma

    DEFF Research Database (Denmark)

    Lyhne, Dorte; Lock-Andersen, Jørgen; Dahlstrøm, Karin;

    2011-01-01

    Abstract Merkel cell carcinoma (MCC) is a rare, aggressive, skin cancer of obscure histogenesis, the incidence of which is rising. There is no consensus on the optimal treatment. Our aim was to evaluate the staging, investigation, treatment, and follow-up of MCC in eastern Denmark, and to investi......Abstract Merkel cell carcinoma (MCC) is a rare, aggressive, skin cancer of obscure histogenesis, the incidence of which is rising. There is no consensus on the optimal treatment. Our aim was to evaluate the staging, investigation, treatment, and follow-up of MCC in eastern Denmark...

  7. Incidence, etiology and mortality of cirrhosis

    DEFF Research Database (Denmark)

    Dam Fialla, Annette; Schaffalitzky de Muckadell, Ove B; Touborg Lassen, Annmarie

    2012-01-01

    Knowledge on the prognosis among patients with cirrhosis is mainly based on clinical trials with selected patient groups as well as population-based register studies with suboptimal diagnostic reliability. The aim of the study was to describe incidence, etiology, and mortality of well-validated c......Knowledge on the prognosis among patients with cirrhosis is mainly based on clinical trials with selected patient groups as well as population-based register studies with suboptimal diagnostic reliability. The aim of the study was to describe incidence, etiology, and mortality of well...

  8. Circumferential resonance modes of solid elastic cylinders excited by obliquely incident acoustic waves.

    Science.gov (United States)

    Fan, Ying; Honarvar, Farhang; Sinclair, Anthony N; Jafari, Mohammad-Reza

    2003-01-01

    When an immersed solid elastic cylinder is insonified by an obliquely incident plane acoustic wave, some of the resonance modes of the cylinder are excited. These modes are directly related to the incidence angle of the insonifying wave. In this paper, the circumferential resonance modes of such immersed elastic cylinders are studied over a large range of incidence angles and frequencies and physical explanations are presented for singular features of the frequency-incidence angle plots. These features include the pairing of one axially guided mode with each transverse whispering gallery mode, the appearance of an anomalous pseudo-Rayleigh in the cylinder at incidence angles greater than the Rayleigh angle, and distortional effects of the longitudinal whispering gallery modes on the entire resonance spectrum of the cylinder. The physical explanations are derived from Resonance Scattering Theory (RST), which is employed to determine the interior displacement field of the cylinder and its dependence on insonification angle.

  9. Incidence of metachronous contralateral breast cancer in Denmark 1978–2009

    DEFF Research Database (Denmark)

    Rasmussen, Christina Bording; Kjaer, Susanne K.; Ejlertsen, Bent;

    2014-01-01

    adjustments were made by use of Poisson regression models. RESULTS: The incidence of CBC decreased with increasing age at first breast cancer. Before 1998, incidence rates of CBC showed little variation. The rates decreased by period of first primary from 546 per 10(5) person-years in 1993-97 to 328 per 10......(5) person-years in 2003-09. After adjustment for age and calendar period, no clear trend was observed in the overall incidence according to time since first breast cancer. CONCLUSIONS: Occurrence of cancer in the contralateral breast seems to be rather independent of time passed since the first primary......BACKGROUND: Incidence of contralateral breast cancer (CBC) is much less studied than primary breast cancer. We aimed to assess incidence rates of CBC in relation to age, calendar period and time since first breast cancer. METHODS: Using the nationwide Danish Cancer Registry, we identified 85 863...

  10. Hazmat 10 Year Incident Summary Reports - Data Mining Tool

    Data.gov (United States)

    Department of Transportation — Series of Incident data and summary statistics reports produced which provide statistical information on incidents by type, year, geographical location, and others....

  11. Hazmat Yearly Incident Summary Reports - Data Mining Tool

    Data.gov (United States)

    Department of Transportation — Series of Incident data and summary statistics reports produced which provide statistical information on incidents by type, year, geographical location, and others....

  12. Predicting Cumulative Incidence Probability by Direct Binomial Regression

    DEFF Research Database (Denmark)

    Scheike, Thomas H.; Zhang, Mei-Jie

    Binomial modelling; cumulative incidence probability; cause-specific hazards; subdistribution hazard......Binomial modelling; cumulative incidence probability; cause-specific hazards; subdistribution hazard...

  13. Current cancer incidence and trends in Yaounde, Cameroon

    Directory of Open Access Journals (Sweden)

    Enow Orock GE

    2014-05-01

    Full Text Available Background: Except for some information on relative frequencies of different cancers in selected areas, the epidemiology of cancer in Cameroon is relatively unknown. Though there is no reliable data on its incidence and pattern, with an estimated 15,000 new cases diagnosed annually and a prevalence of about 25.000 cases throughout the country, cancer is being increasingly recognized as a public health problem in Cameroon. The Yaounde Cancer Registry is a population registry physically located at the General Hospital Yaounde that has been operating since 2004. It collects data from about 20 sources that cover the entire population of Yaounde estimated in 2010 at about 1,299,369. Objectives: The objective of this study was to find out the incidence and trends of cancer in the Yaounde population in the period 2004 – 2006/2010 – 2011. It is hoped that this will enable policy makers, health providers and other stake holders plan appropriate health management policy in this population. Materials and Methods: This report presents the cancer incidence for 5 years, 2004 – 2006/2010 – 2011 in the Yaounde population estimated at 1,299,369. Data of the Yaounde Cancer Registry was reviewed for the period under study using Canreg5 software. Only malignant cases registered during the period under study were used in the analysis while benign and other uncertain tumours were excluded. The 2010 census estimates by the National Institute of Statistics was employed to calculate the incidence, age-standardized and crude rates. Other software like excel, epi info were also used for analysis. Survival studies were not carried out in this study. Results: A total of 4,689 new malignant cases were reported, of which 2,901 (68% were females and 1,788 (32% were males. The incidence showed an average of 358 for men and 580 for women. The average age of cancer patients in Yaounde is 44.8 years. Morphologically confirmed cases accounted for 89% .The annual number of

  14. The incidence and related risk factors of severe hypoglycemia in type 1 diabetic patients in Gaugndong Province%广东省1型糖尿病严重低血糖发病率及危险因素分析

    Institute of Scientific and Technical Information of China (English)

    李津; 吴建能; 李路; 方懿珊; 袁琳; 林健才; 陈定宇; 罗国春; 孙辽; 翁建平; 杨黛稚; 林少达; 梁干雄; 陈立曙; 郎江明; 张秀薇; 武革; 李绍清

    2012-01-01

    Objective To investigate the incidence and the related risk factors of severe hypoglycemia in patients with type 1 diabetes. Methods The demographic data, medical history, and hemoglobin A1C ( HbA1c ) and stimulated C peptide levels were collected the patients with established type 1 diabetes in 16 hospitals in Guangdong Province. The risk factors of onset and recurrence of severe hypoglycemia were analyzed with Poisson regression model and Backwards step-wise logistic regression analysis, respectively. Results A total of 611 patients were enrolled. The overall incidence of severe hypoglycemia was 70. 6/100 patient -years. The significant predictors of severe hypoglycemia were male ( RR = 1. 69 ), medical insurance claiming percentage below 50% ( RR = 1. 38 ), long diabetes duration ( RR = 1. 23 ), underweight ( RR = 1. 43 ), uncontrolled diet ( RR = 2. 05 ), exercise less than 150min/w ( RR = 1. 61 ), neuropathy ( RR = 2. 00 ), smoking ( RR = 1. 46 ) as well as lower HbA1 c ( RR = 1. 47 ). Overweight or obesity was a protective factor ( RR = 0. 60 ). Totally, 81. 1% of severe hypoglycemia episodes occurred in 16. 2% of type 1 diabetic patients with recurrent e-vents ( no less than 2 episodes ). The recurrence of severe hypoglycemia was significantly associated with male ( RR = 2. 03 ), underweight ( RR = 2. 02 ), uncontrolled diet (RR=3.ll), exercise less than 150 min/w ( RR = 2. 87 ) as well as lower HbA1c( RR = 1. 73 ). Overweight or obesity was also a protective factor ( RR =0. 28 ). Conclusion In summary, high incidence of severe hypoglycemia in type 1 diabetic patients is revealed in this study. Moreover, we confirm that severe hypoglycemia is recurrent in high - risk patients. Comprehensive management should be taken against some modifiable risk factors in these patients.%目的 调查1型糖尿病患者严重低血糖的发病率及其危险因素.方法 自2010年 8月 6日至2012年 3月31日在广东省16家医院收集1型糖尿病患者的人口学资

  15. Doppler shift generated by a moving diffraction grating under incidence by polychromatic diffuse light

    CERN Document Server

    Dossou, Kokou B

    2016-01-01

    We consider the spectral response of moving diffraction gratings, in which the incident light extends over a broad angular range and where the diffracted light is observed from a specific angle. We show that the dispersion relation between the frequency perceived by an observer who is looking at a moving grating and the incident frequency can exhibit some unique features, such as a flat band (i.e., a local minimum). An observer can see the light diffracted into a non-specular diffraction order from a multitude of incident light rays and the angle of incidence of each ray is frequency-dependent; as a consequence, when the grating is moving, each incident ray experiences a Doppler shift in frequency that depends on its angle of incidence. We find that remarkable features appear near a Wood anomaly where the angle of incidence, for a given diffraction angle, can change very quickly with frequency. This means that light of multiple frequencies and incident from multiple angles can be mixed by the motion of the gr...

  16. Cancer incidence and mortality in Chukotka, 1997–2010

    Directory of Open Access Journals (Sweden)

    Alexey A. Dudarev

    2013-03-01

    Full Text Available Objectives. The general aim was to assess cancer incidence and mortality among the general population of Chukotka in 1997–2010 and to compare it with the population of Russia. Methods. Cancer data were abstracted from the annual statistical reports of the P.A. Hertzen Research Institute of Oncology in Moscow. The annual number and percent of cases, crude and age-standardized cancer incidence (ASIR and mortality (ASMR rates per 100,000 among men and women in the Chukotka Autonomous Okrug were determined for the period 1997–2010 for incidence and 1999–2010 for mortality. Two years’ data were aggregated to generate temporal trends during the period. In age-standardization, the Segi-Doll world standard population used by the International Agency for Research on Cancer was used. Results. The higher incidence and mortality rate of cancer (all sites combined among men compared to women, which was observed in Russia nationally, was reflected also in Chukotka, although the difference between men and women was not statistically significant. Overall, the patterns of cancer sites are similar between Chukotka and Russia, with cancer of the lung/trachea/bronchus and stomach occupying the top ranks among men. Oesophageal cancer is common in Chukotka but not in Russia, whereas prostate cancer is common in Russia but not in Chukotka. Among women, breast cancer is either the commonest or second commonest cancer in terms of incidence or mortality in both Chukotka and Russia. Cancer of the lung/trachea/bronchi ranks higher in Chukotka than in Russia. The rate of cancer incidence and mortality for all sites combined during the 13-year period was relatively stable in Russia. Dividing the period into two halves, an increase among both men and women was observed in Chukotka for all sites combined, and also for colorectal cancer. Conclusions. This paper presents previously unavailable cancer epidemiological data on Chukotka. They provide a basis for comparative

  17. Cancer incidence and mortality in Chukotka, 1997–2010

    Science.gov (United States)

    Dudarev, Alexey A.; Chupakhin, Valery S.; Odland, Jon Øyvind

    2013-01-01

    Objectives The general aim was to assess cancer incidence and mortality among the general population of Chukotka in 1997–2010 and to compare it with the population of Russia. Methods Cancer data were abstracted from the annual statistical reports of the P.A. Hertzen Research Institute of Oncology in Moscow. The annual number and percent of cases, crude and age-standardized cancer incidence (ASIR) and mortality (ASMR) rates per 100,000 among men and women in the Chukotka Autonomous Okrug were determined for the period 1997–2010 for incidence and 1999–2010 for mortality. Two years’ data were aggregated to generate temporal trends during the period. In age-standardization, the Segi-Doll world standard population used by the International Agency for Research on Cancer was used. Results The higher incidence and mortality rate of cancer (all sites combined) among men compared to women, which was observed in Russia nationally, was reflected also in Chukotka, although the difference between men and women was not statistically significant. Overall, the patterns of cancer sites are similar between Chukotka and Russia, with cancer of the lung/trachea/bronchus and stomach occupying the top ranks among men. Oesophageal cancer is common in Chukotka but not in Russia, whereas prostate cancer is common in Russia but not in Chukotka. Among women, breast cancer is either the commonest or second commonest cancer in terms of incidence or mortality in both Chukotka and Russia. Cancer of the lung/trachea/bronchi ranks higher in Chukotka than in Russia. The rate of cancer incidence and mortality for all sites combined during the 13-year period was relatively stable in Russia. Dividing the period into two halves, an increase among both men and women was observed in Chukotka for all sites combined, and also for colorectal cancer. Conclusions This paper presents previously unavailable cancer epidemiological data on Chukotka. They provide a basis for comparative studies across

  18. Genetic and environmental factors associated with incidence of infectious bovine keratoconjunctivitis in preweaned beef calves.

    Science.gov (United States)

    Snowder, G D; Van Vleck, L D; Cundiff, L V; Bennett, G L

    2005-03-01

    Infectious bovine keratoconjunctivitis (IBK) is one of the most economically important diseases in preweaned calves. This study examined the health records of 45,497 calves over a 20-yr period to determine environmental and genetic factors influencing the incidence of IBK. Three data sets were analyzed with an animal model. The first data set (n = 41,986) evaluated environmental factors and genetic differences among nine purebred (Angus, Braunvieh, Charolais, Gelbvieh, Hereford, Limousin, Pinzgauer, Red Poll, and Simmental) and three composite breeds (MARC I, MARC II, and MARC III). Weaning weights of calves diagnosed with IBK were 8.9 kg lighter (P < 0.05) than weights of healthy calves. Incidence of IBK was related to age of the calf and the seasonal life cycle of the face fly (Musca autumnalis). Incidence of IBK increased in the spring (June), peaked during the summer months (July to September), and then decreased in the fall. Herefords were the most susceptible breed (P < 0.05) compared with all other purebreds and composites. Estimates of direct heritability for the incidence of IBK were generally low and ranged from 0.00 to 0.28 by breed. The maternal permanent environmental and genetic effects of the dam on the incidence of IBK were not significant for most breeds. The second data set (n = 9,606) was used to estimate heterosis for the incidence of IBK from a Hereford and Angus diallel design. The heterosis effect for the incidence of IBK in reciprocal Hereford/Angus crossbred calves was slightly negative (P = 0.12) but not large. The higher incidence of IBK in Angus x Hereford calves compared with Hereford x Angus calves (13.3 vs. 8.9%) suggests a maternal effect related to the incidence of IBK. Incidence of IBK in crossbred calves sired by tropically adapted breeds (Brahma, Boran, Tuli) compared with purebred and crossbred Bos taurus types was investigated in the third data set (n = 2,622). Crossbred calves sired by tropically adapted breeds had a lower

  19. [Patient-safety incidents in general practice

    NARCIS (Netherlands)

    Gaal, S.; Smits, M.; Verstappen, W.H.J.M.; Giesen, P.H.J.; Wensing, M.J.P.

    2011-01-01

    OBJECTIVE: To gain insight into the frequency, severity, causes and consequences of potentially preventable patient-safety incidents in Dutch primary care. DESIGN: Retrospective medical record review study. METHOD: We screened a sample of 1000 medical records in 20 general practices and 1145 medical

  20. The value of reconstruction of radiation incidents

    International Nuclear Information System (INIS)

    A film badge, or thermoluminescent personal dosemeter, as a means of assessing personal radiation dose is adequate under normal working exposure circumstances. However, in a radiation incident where the direction, dimensions and gradient of the radiation field may be of prime importance, the personal dosemeter does not always indicate a dose which is representative of whole body or partial body dose. Reconstruction of such an incident is therefore essential in determining these parameters. In this paper, reference will be to the need for prompt reconstruction, the value of a search interview and repeated re-enactment of the incident. It will emphasize the need for a personal dosemeter, and describe how the recorded dose may be used as a basis for substantiating both the information derived from the search interview and subsequent physical and radiation measurements. These measurements are used to predict the partial and average whole body exposures, which in turn may be compared to the assessment of radiation exposure indicated by a study of the chormosome aberration yield in human lymphocytes. The principles involved here are discussed with reference to an incident involving the over-exposure of two radiographers working in an industrial environment

  1. Low-Incidence, High-Consequence Pathogens

    Centers for Disease Control (CDC) Podcasts

    2014-02-21

    Dr. Stephan Monroe, a deputy director at CDC, discusses the impact of low-incidence, high-consequence pathogens globally.  Created: 2/21/2014 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 2/26/2014.

  2. 49 CFR 1542.307 - Incident management.

    Science.gov (United States)

    2010-10-01

    ... program; (2) Initiate appropriate action as specified in the Airport Emergency Plan under 14 CFR 139.325... required to have a security program under § 1542.103(c) but not subject to 14 CFR part 139, must develop... 49 Transportation 9 2010-10-01 2010-10-01 false Incident management. 1542.307 Section...

  3. 42 CFR 73.14 - Incident response.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Incident response. 73.14 Section 73.14 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES QUARANTINE, INSPECTION, LICENSING... response procedures for the theft, loss, or release of a select agent or toxin, inventory...

  4. 78 FR 38878 - Critical Incident Stress Plans

    Science.gov (United States)

    2013-06-28

    ... definition. Similarly, as explained below, ``near miss'' scenarios (i.e., situations which when seen in... of a critical incident. Additionally, this proposed rule does not directly apply to ``near miss'' scenarios. A ``near miss'' is an event, seen in hindsight, in which an accident could have occurred, but...

  5. [Cancer incidence in the military: an update].

    Science.gov (United States)

    Peragallo, Mario Stefano; Urbano, Francesco; Sarnicola, Giuseppe; Lista, Florigio; Vecchione, Alfredo

    2011-01-01

    An abnormally elevated rate of Hodgkin's lymphoma was reported in 2001 among Italian soldiers in Bosnia and Kosovo since 1995: a surveillance system was therefore set up for the military community. Preliminary results for a longer period (1996-2007) have shown incidence rates lower than expected for all malignancies. No significant difference was registered between observed and expected cases of Hodkin's lymphoma: the excess of reported cases for this malignancy in 2001-2002 was probably due to a peak occurred in 2000 among the whole military; it is therefore unrelated to deployment in the Balkans, and probably represents a chance event. Moreover, a significant excess of thyroid cancer was reported among the whole military.The estimated number of incident cases, including those missed by the surveillance system, was not significantly higher than expected for all cancers; conversely, the estimated incidence rate of thyroid cancer was significantly increased; this excess, however, is probably due to a selection bias.These data concerning cancer surveillance in the Italian military are consistent with lacking evidence of an increased cancer incidence among troops of other countries deployed in the areas of Iraq, Bosnia, and Kosovo, where armour penetrating depleted uranium shells have been used. However, a comprehensive assessment of cancer morbidity in the military requires a revision of the privacy regulations, in order to link individual records of military personnel and data bases of the National Health Service. PMID:22166781

  6. Incident Investigation in SMS and FRMS

    NARCIS (Netherlands)

    Stewart, S.; Koornneef, F.; Akselsson, R.; Kingston, J.; Stewart, D.

    2009-01-01

    Chapter 4: Incident Investigation in SMS and FRMS The European Commission HILAS project (Human Integration into the Lifecycle of Aviation Systems - a project supported by the European Commission’s 6th Framework between 2005-2009) was focused on using human factors knowledge and methodology to addre

  7. Urbanisation and the incidence of eating disorders.

    NARCIS (Netherlands)

    Son, G.E. van; Hoeken, D. van; Bartelds, A.I.M.; Furth, E.F. van; Hoek, H.W.

    2006-01-01

    The link between degree of urbanisation and a number of mental disorders is well established. Schizophrenia, psychosis and depression are known to occur more frequently in urban areas. In our primary care-based study of eating disorders, the incidence of bulimia nervosa showed a dose response relati

  8. The incidence of anorexia nervosa on Curacao

    NARCIS (Netherlands)

    Hoek, HW; van Harten, PN; Hermans, KME; Katzman, MA; Matroos, GE; Susser, ES

    2005-01-01

    Objective: Although anorexia nervosa was once thought to occur only in affluent societies, cases have now been documented across the globe. To examine whether anorexia nervosa emerges in societies undergoing socioeconomic transition, the authors studied the incidence of anorexia nervosa on the Carib

  9. National Toxic Substance Incidents Program (NTSIP)

    Centers for Disease Control (CDC) Podcasts

    2011-02-03

    This podcast gives an overview of the three components of the National Toxic Substance Incidents Program: state surveillance, national database, and response teams.  Created: 2/3/2011 by Agency for Toxic Substances and Disease Registry.   Date Released: 2/3/2011.

  10. Assessment of Stubborn Disease Incidence in Citrus

    Science.gov (United States)

    Citrus stubborn disease, caused by Spiroplasma Citri, has occured in California for more than 90 years, however, detection methods for estimating disease incidence have not been well developed. Two 8 ha plots in Kern Co. CA were established and sampled in July and August, 2006. Different tissues o...

  11. IT Security Vulnerability and Incident Response Management

    NARCIS (Netherlands)

    Hafkamp, W.H.M.; Paulus, S.; Pohlman, N.; Reimer, H.

    2006-01-01

    This paper summarises the results of a Dutch PhD research project on IT security vulnerability and incident response management, which is supervised by the University of Twente in the Netherlands and which is currently in its final stage. Vulnerabilities are ‘failures or weaknesses in computer (appl

  12. Urbanisation and the incidence of eating disorders

    NARCIS (Netherlands)

    Van Son, Gabrielle E.; Van Hoeken, Daphne; Bartelds, Aad I. M.; Van Furth, Eric F.; Hoek, Hans W.

    2006-01-01

    The link between degree of urbanisation and a number of mental disorders is well established. Schizophrenia, psychosis and depression are known to occur more frequently in urban areas. In our primary care-based study of eating disorders, the incidence of bulimia nervosa showed a dose-response relati

  13. Incident response monitoring technologies for aircraft cabin

    NARCIS (Netherlands)

    Havermans, J.B.G.A.; Houtzager, M.M.G.; Jacobs, P.

    2015-01-01

    The Netherlands Organization for Applied Scientific Research (TNO) was granted by ASHRAE (1306-RP) to conduct scientfic review and feasibility analysis of technologies and methods for measuring aircraft power system contaminants in the cabin air during unanticipated adverse incidents. In particular,

  14. Assessment of Stubborn Disease Incidence in Citrus

    Science.gov (United States)

    Citrus stubborn disease (CSD) has been a problem in California for over 90 years, yet, methods for rapidly detecting its causal agent, Spiroplasma citri, for use in estimating disease incidence have not been optimized. Two 8 ha blocks within two commercial groves were sampled in July and August, 20...

  15. Cyberbullying: Incidence, Evidence and Solutions : Video Presentation

    OpenAIRE

    O'Neill, Brian

    2015-01-01

    Presentation by Professor Brian O'Neill (DIT), "Cyberbullying: Incidence, Evidence and Solutions". Delivered at Dublin Institute of Technology, Aungier St, Dublin 2 on 26th June 2015. - See more at: http://lttc.dit.ie/lttc/elearning/elearningsummerschool/pastsummerschools/summerschool2015/elss15videopresentations/#sthash.cge2gwYH.dpuf

  16. Nervous System and Intracranial Tumour Incidence by Ethnicity in England, 2001-2007: A Descriptive Epidemiological Study.

    Directory of Open Access Journals (Sweden)

    Edward J Maile

    Full Text Available There is substantial variation in nervous system and intracranial tumour incidence worldwide. UK incidence data have limited utility because they group these diverse tumours together and do not provide data for individual ethnic groups within Blacks and South Asians. Our objective was to determine the incidence of individual tumour types for seven individual ethnic groups.We used data from the National Cancer Intelligence Network on tumour site, age, sex and deprivation to identify 42,207 tumour cases. Self-reported ethnicity was obtained from the Hospital Episode Statistics database. We used mid-year population estimates from the Office for National Statistics. We analysed tumours by site using Poisson regression to estimate incidence rate ratios comparing non-White ethnicities to Whites after adjustment for sex, age and deprivation.Our study showed differences in tumour incidence by ethnicity for gliomas, meningiomas, pituitary tumours and cranial and paraspinal nerve tumours. Relative to Whites; South Asians, Blacks and Chinese have a lower incidence of gliomas (p<0.01, with respective incidence rate ratios of 0.68 (confidence interval: 0.60-0.77, 0.62 (0.52-0.73 and 0.58 (0.41-0.83. Blacks have a higher incidence of meningioma (p<0.01 with an incidence rate ratio of 1.29 (1.05-1.59 and there is heterogeneity in meningioma incidence between individual South Asian ethnicities. Blacks have a higher incidence of pituitary tumours relative to Whites (p<0.01 with an incidence rate ratio of 2.95 (2.37-3.67. There is heterogeneity in pituitary tumour incidence between individual South Asian ethnicities.We present incidence data of individual tumour types for seven ethnic groups. Current understanding of the aetiology of these tumours cannot explain our results. These findings suggest avenues for further work.

  17. Reported fatal and non-fatal incidents involving tourists in Hawaii Volcanoes National Park, 1992-2002.

    Science.gov (United States)

    Heggie, Travis W

    2005-08-01

    Objectives. To examine fatal and non-fatal incidents involving tourists in Hawaii Volcanoes National Park. Methods. Official press releases from the public relations office at Hawaii Volcanoes National Park were examined for reports of fatal and non-fatal incidents involving tourists. Results. Between 1992 and 2002 there were 65 press releases reporting 40 fatalities, 45 serious injuries, 53 minor injuries, and 25 no injury events. Severity information was unavailable for four additional tourists. Aircraft and backcountry incidents each accounted for 30% of all incidents followed by road incidents (22%) and frontcountry incidents (17%). Aircraft incidents reported 17 fatalities, backcountry incidents accounted for 10 fatalities, frontcountry incidents reported seven fatalities, and road incidents totaled six fatalities. One fatality was classified as a suicide. Backcountry (23) and road (10) incidents had the highest number of serious incidents. Male tourists (62) were more frequently involved in incidents than female tourists (41) and tourists aged 20-29 years and 40-49 years accounted for the highest number of fatalities and total incidents. Conclusions. Helicopter tours, hiking in areas with active lava flows, falls into steam vents and earthcracks, and driving unfamiliar rental cars in unfamiliar locations are the major activities resulting in death and serious injury. Additional factors such as tourists ignoring warning signs, wandering off-trail or hiking at night, tourists misinformed by guidebooks and other tourists, and tourists with pre-existing heart and asthma conditions are contributing causes in many incidents. The findings of this study provide information that allows prospective tourists, tourism managers, and travel health providers make informed decisions that promote safe tourism and can aid future efforts in developing preventative strategies at tourist destinations with similar environments and activities. However, in order for preventative

  18. Tuberculosis incidence in prisons: a systematic review.

    Directory of Open Access Journals (Sweden)

    Iacopo Baussano

    Full Text Available BACKGROUND: Transmission of tuberculosis (TB in prisons has been reported worldwide to be much higher than that reported for the corresponding general population. METHODS AND FINDINGS: A systematic review has been performed to assess the risk of incident latent tuberculosis infection (LTBI and TB disease in prisons, as compared to the incidence in the corresponding local general population, and to estimate the fraction of TB in the general population attributable (PAF% to transmission within prisons. Primary peer-reviewed studies have been searched to assess the incidence of LTBI and/or TB within prisons published until June 2010; both inmates and prison staff were considered. Studies, which were independently screened by two reviewers, were eligible for inclusion if they reported the incidence of LTBI and TB disease in prisons. Available data were collected from 23 studies out of 582 potentially relevant unique citations. Five studies from the US and one from Brazil were available to assess the incidence of LTBI in prisons, while 19 studies were available to assess the incidence of TB. The median estimated annual incidence rate ratio (IRR for LTBI and TB were 26.4 (interquartile range [IQR]: 13.0-61.8 and 23.0 (IQR: 11.7-36.1, respectively. The median estimated fraction (PAF% of tuberculosis in the general population attributable to the exposure in prisons for TB was 8.5% (IQR: 1.9%-17.9% and 6.3% (IQR: 2.7%-17.2% in high- and middle/low-income countries, respectively. CONCLUSIONS: The very high IRR and the substantial population attributable fraction show that much better TB control in prisons could potentially protect prisoners and staff from within-prison spread of TB and would significantly reduce the national burden of TB. Future studies should measure the impact of the conditions in prisons on TB transmission and assess the population attributable risk of prison-to-community spread. Please see later in the article for the Editors' Summary.

  19. Spatial Analysis of Stomach Cancer Incidence in Iran.

    Science.gov (United States)

    Pakzad, Reza; Khani, Yousef; Pakzad, Iraj; Momenimovahed, Zohre; Mohammadian-Hashejani, Abdollah; Salehiniya, Hamid; Towhidi, Farhad; Makhsosi, Behnam Reza

    2016-01-01

    Stomach cancer, the fourth most common cancer and the second leading cause of cancer-related death through the world, is very common in parts of Iran. Geographic variation in the incidence of stomach cancer is due to many different factors. The aim of this study was to assess the geographical and spatial distribution of stomach cancer in Iran using data from the cancer registry program in Iran for the year 2009. The reported incidences of stomach cancer for different provinces were standardized to the world population structure. ArcGIS software was used to analyse the data. Hot spots and high risk areas were determined using spatial analysis (Getis-Ord Gi). Hot and cold spots were determined as more than or less than 2 standard deviations from the national average, respectively. A significance level of 0.10 was used for statistical judgment. In 2009, a total of 6,886 cases of stomach cancers were reported of which 4,891 were in men and 1,995 in women (standardized incidence rates of 19.2 and 10.0, respectively, per 100,000 population). The results showed that stomach cancer was concentrated mainly in northwest of the country in both men and women. In women, northwest provinces such as Ardebil, East Azerbaijan, West Azerbaijan, Gilan, and Qazvin were identified as hot spots (pstomach cancer is clustered in the northwest of the country, further epidemiological studies are needed to identify factors contributing to this concentration.

  20. [Epidemiological analysis of the incidence of varicose pathology in pregnancy].

    Science.gov (United States)

    Dindelli, M; Basellini, A; Rabaiotti, E; Corsi, G; Ferrari, P A; Zucca, R; Ferrari, A

    1990-01-01

    One thousand and fourteen women who were delivered in the Obst. Gynec. Clinic "L. Mangiagalli" were investigated to evaluate the real incidence of varicose disease, its correlation with some factors and the development of complication. The observation period was comprised between the 1st and the 4th day of puerperium in which women were investigated by obstetricians through a detailed questionnaire and underwent an angiological visit. The mean age of the puerperae was 29.6 years (range 15-47 yrs); 587 women were primiparas (57.9%). The prevalence of varicose disease's different aspects resulted 57.9%, while the incidence related to pregnancy was 26.1%. The prevalence and the incidence resulted to be respectively 26.8% and 14.4% for varicosities, 5.6% and 3.1% for saphenous varicosis. Complications were observed in 10 patients (0.99%). 45.3% of patients reported family positivity for varicose disease; this group has shown a statistically significant difference (p less than 0.01) for the onset of different aspects of varicose syndrome. PMID:2088157